Automated force volume image processing for biological samples.

Directory of Open Access Journals (Sweden)

Pavel Polyakov

2011-04-01

Full Text Available Atomic force microscopy (AFM has now become a powerful technique for investigating on a molecular level, surface forces, nanomechanical properties of deformable particles, biomolecular interactions, kinetics, and dynamic processes. This paper specifically focuses on the analysis of AFM force curves collected on biological systems, in particular, bacteria. The goal is to provide fully automated tools to achieve theoretical interpretation of force curves on the basis of adequate, available physical models. In this respect, we propose two algorithms, one for the processing of approach force curves and another for the quantitative analysis of retraction force curves. In the former, electrostatic interactions prior to contact between AFM probe and bacterium are accounted for and mechanical interactions operating after contact are described in terms of Hertz-Hooke formalism. Retraction force curves are analyzed on the basis of the Freely Jointed Chain model. For both algorithms, the quantitative reconstruction of force curves is based on the robust detection of critical points (jumps, changes of slope or changes of curvature which mark the transitions between the various relevant interactions taking place between the AFM tip and the studied sample during approach and retraction. Once the key regions of separation distance and indentation are detected, the physical parameters describing the relevant interactions operating in these regions are extracted making use of regression procedure for fitting experiments to theory. The flexibility, accuracy and strength of the algorithms are illustrated with the processing of two force-volume images, which collect a large set of approach and retraction curves measured on a single biological surface. For each force-volume image, several maps are generated, representing the spatial distribution of the searched physical parameters as estimated for each pixel of the force-volume image.

Fort Stewart integrated resource assessment. Volume 3: Resource assessment

Energy Technology Data Exchange (ETDEWEB)

Sullivan, G.P.; Keller, J.M.; Stucky, D.J.; Wahlstrom, R.R.; Larson, L.L.

1993-10-01

The US Army Forces Command (FORSCOM) has tasked the US Department of Energy (DOE) Federal Energy Management Program (FEMP), supported by the Pacific Northwest Laboratory, to identify, evaluate, and assist in acquiring all cost-effective energy projects at Fort Stewart. This is part of a model program that PNL is designing to support energy-use decisions in the federal sector. This report provides the results of the fossil fuel and electric energy resource opportunity (ERO) assessments performed by PNL at the FORSCOM Fort Stewart facility located approximately 25 miles southwest of Savannah, Georgia. It is a companion report to Volume 1, Executive Summary, and Volume 2, Baseline Detail. The results of the analyses of EROs are presented in 11 common energy end-use categories (e.g., boilers and furnaces, service hot water, and building lighting). A narrative description of each ERO is provided, along with a table detailing information on the installed cost, energy and dollar savings; impacts on operations and maintenance (O&M); and, when applicable, a discussion of energy supply and demand, energy security, and environmental issues. A description of the evaluation methodologies and technical and cost assumptions is also provided for each ERO. Summary tables present the cost-effectiveness of energy end-use equipment before and after the implementation of each ERO. The tables also present the results of the life-cycle cost (LCC) analysis indicating the net present value (NPV) and savings to investment ratio (SIR) of each ERO.

Strategic Plan for the U.S. Geological Survey. Status and Trends of Biological Resources Program: 2004-2009

National Research Council Canada - National Science Library

Dresler, Paul V; James, Daniel L; Geissler, Paul H; Bartish, Timothy M; Coyle, James

2004-01-01

The mission of the USGS Status and Trends of Biological Resources Program is to measure, predict, assess, and report the status and trends of the Nation's biological resources to facilitate research...

Book review: Biology and conservation of martens, sables, and fishers: A new synthesis

Science.gov (United States)

Jenkins, Kurt J.

2013-01-01

Mammals of the genus Martes, including martens, sables, and fishers, are mid-sized carnivores inhabiting many forested ecosystems throughout regions of North America, Europe, and Asia. This volume provides a comprehensive synthesis of the current state of knowledge pertaining to the biology and conservation of Martes species throughout the world. This volume will be an essential resource for mammalogists, resource managers, and applied ecologists involved in research or conservation of martens, sables, and fishers. For that matter, anyone seeking a full immersion in the modern world of Martes biology and conservation will not be disappointed. The volume has been carefully edited and reviewed, and the thoroughness with which the authors present and interpret recent advances in their specialty areas is really quite impressive.

Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources.

Science.gov (United States)

Waagmeester, Andra; Kutmon, Martina; Riutta, Anders; Miller, Ryan; Willighagen, Egon L; Evelo, Chris T; Pico, Alexander R

2016-06-01

The diversity of online resources storing biological data in different formats provides a challenge for bioinformaticians to integrate and analyse their biological data. The semantic web provides a standard to facilitate knowledge integration using statements built as triples describing a relation between two objects. WikiPathways, an online collaborative pathway resource, is now available in the semantic web through a SPARQL endpoint at http://sparql.wikipathways.org. Having biological pathways in the semantic web allows rapid integration with data from other resources that contain information about elements present in pathways using SPARQL queries. In order to convert WikiPathways content into meaningful triples we developed two new vocabularies that capture the graphical representation and the pathway logic, respectively. Each gene, protein, and metabolite in a given pathway is defined with a standard set of identifiers to support linking to several other biological resources in the semantic web. WikiPathways triples were loaded into the Open PHACTS discovery platform and are available through its Web API (https://dev.openphacts.org/docs) to be used in various tools for drug development. We combined various semantic web resources with the newly converted WikiPathways content using a variety of SPARQL query types and third-party resources, such as the Open PHACTS API. The ability to use pathway information to form new links across diverse biological data highlights the utility of integrating WikiPathways in the semantic web.

Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources.

Directory of Open Access Journals (Sweden)

Andra Waagmeester

2016-06-01

Full Text Available The diversity of online resources storing biological data in different formats provides a challenge for bioinformaticians to integrate and analyse their biological data. The semantic web provides a standard to facilitate knowledge integration using statements built as triples describing a relation between two objects. WikiPathways, an online collaborative pathway resource, is now available in the semantic web through a SPARQL endpoint at http://sparql.wikipathways.org. Having biological pathways in the semantic web allows rapid integration with data from other resources that contain information about elements present in pathways using SPARQL queries. In order to convert WikiPathways content into meaningful triples we developed two new vocabularies that capture the graphical representation and the pathway logic, respectively. Each gene, protein, and metabolite in a given pathway is defined with a standard set of identifiers to support linking to several other biological resources in the semantic web. WikiPathways triples were loaded into the Open PHACTS discovery platform and are available through its Web API (https://dev.openphacts.org/docs to be used in various tools for drug development. We combined various semantic web resources with the newly converted WikiPathways content using a variety of SPARQL query types and third-party resources, such as the Open PHACTS API. The ability to use pathway information to form new links across diverse biological data highlights the utility of integrating WikiPathways in the semantic web.

Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources

Science.gov (United States)

Waagmeester, Andra; Pico, Alexander R.

2016-01-01

The diversity of online resources storing biological data in different formats provides a challenge for bioinformaticians to integrate and analyse their biological data. The semantic web provides a standard to facilitate knowledge integration using statements built as triples describing a relation between two objects. WikiPathways, an online collaborative pathway resource, is now available in the semantic web through a SPARQL endpoint at http://sparql.wikipathways.org. Having biological pathways in the semantic web allows rapid integration with data from other resources that contain information about elements present in pathways using SPARQL queries. In order to convert WikiPathways content into meaningful triples we developed two new vocabularies that capture the graphical representation and the pathway logic, respectively. Each gene, protein, and metabolite in a given pathway is defined with a standard set of identifiers to support linking to several other biological resources in the semantic web. WikiPathways triples were loaded into the Open PHACTS discovery platform and are available through its Web API (https://dev.openphacts.org/docs) to be used in various tools for drug development. We combined various semantic web resources with the newly converted WikiPathways content using a variety of SPARQL query types and third-party resources, such as the Open PHACTS API. The ability to use pathway information to form new links across diverse biological data highlights the utility of integrating WikiPathways in the semantic web. PMID:27336457

Biological modelling of fuzzy target volumes in 3D radiotherapy

International Nuclear Information System (INIS)

Levegruen, S.; Kampen, M. van; Waschek, T.; Engenhart, R.; Schlegel, W.

1995-01-01

increase in NTCP is then calculated for a homogeneous dose distribution extending the boundaries of the volume considered towards the maximal PTV. Results: The behavior of the model and its dependence on the input parameters was investigated for the case of a brain tumor. Going from the minimal PTV towards the maximal PTV, the TCP increases show a sigmoidal shape. The increase in NTCP depends for each patient on the relative position of the organs at risk with respect to the region of uncertainty. We use the model as input into a computer assisted expert system based on Fuzzy Logic. Output of the Fuzzy system is the target volume which, for each individual patient, leads to the best compromise between high tumor control probability on one side and a low risk of complications on the other side. With this system the extent of the target volume towards noncritical structures is large, whereas the boundaries near an organ at risk within the region of uncertainty are strongly influenced by the partial volume of that organ at risk irradiated. Conclusion: At present biological models, in particular of TCP, suffer from a lack of data for the biological input parameters, especially for the density and distribution of clonogenic cells. The better these input parameters become established in the future, the more the model described here will serve as an important aid for the radiotherapist in the definition of the optimal target volume

Yucca Mountain Biological resources monitoring program

International Nuclear Information System (INIS)

1991-01-01

The US Department of Energy (US DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a possible site for a geological repository for high-level radioactive waste. To ensure site characterization activities do not adversely affect the Yucca Mountain area, an environmental program, the Yucca Mountain Biological Resources Monitoring Program, has been implemented monitor and mitigate environmental impacts and to ensure activities comply with applicable environmental laws. Potential impacts to vegetation, small mammals, and the desert tortoise (an indigenous threatened species) are addressed, as are habitat reclamation, radiological monitoring, and compilation of baseline data. This report describes the program in Fiscal Years 1989 and 1990. 12 refs., 4 figs., 17 tabs

e-Biologics: Fabrication of Sustainable Electronics with "Green" Biological Materials.

Science.gov (United States)

Lovley, Derek R

2017-06-27

The growing ubiquity of electronic devices is increasingly consuming substantial energy and rare resources for materials fabrication, as well as creating expansive volumes of toxic waste. This is not sustainable. Electronic biological materials (e-biologics) that are produced with microbes, or designed with microbial components as the guide for synthesis, are a potential green solution. Some e-biologics can be fabricated from renewable feedstocks with relatively low energy inputs, often while avoiding the harsh chemicals used for synthesizing more traditional electronic materials. Several are completely free of toxic components, can be readily recycled, and offer unique features not found in traditional electronic materials in terms of size, performance, and opportunities for diverse functionalization. An appropriate investment in the concerted multidisciplinary collaborative research required to identify and characterize e-biologics and to engineer materials and devices based on e-biologics could be rewarded with a new "green age" of sustainable electronic materials and devices. Copyright © 2017 Lovley.

Patrick Air Force Base integrated resource assessment. Volume 3, Resource assessment

Energy Technology Data Exchange (ETDEWEB)

Sandusky, W.F.; Parker, S.A.; King, D.A.; Wahlstrom, R.R.; Elliott, D.B.; Shankle, S.A.

1993-12-01

The US Air Force has tasked the Pacific Northwest Laboratory (PNL) in support of the US Department of Energy Federal Energy Management Program to identify, evaluate, and assist in acquiring all cost effective energy projects at Patrick Air Force Base (AFB). This is part of a model program that PNL is designing to support energy-use decisions in the federal sector. This report provides the results of the fossil fuel and electric energy resource opportunity (ERO) assessments performed by PNL at Patrick AFB which is located south of Cocoa Beach, Florida. It is a companion report to Volume 1, Executive Summary, and Volume.2, Baseline Detail. The results of the analyses of EROs are presented in 11 common energy end-use categories. A narrative description of each ERO is provided, including information on the installed cost, energy and dollar savings, impacts on operations and maintenance, and, when applicable, a discussion of energy supply and demand, energy security, and environmental issues. A description of the evaluation methodologies and technical and cost assumptions is also provided for each ERO. Summary tables present the cost-effectiveness of energy end-use equipment before and after the implementation of each ERO and present the results of the life-cycle cost analysis indicating the net present value and value index of each ERO.

WE-B-304-02: Treatment Planning Evaluation and Optimization Should Be Biologically and Not Dose/volume Based

International Nuclear Information System (INIS)

Deasy, J.

2015-01-01

The ultimate goal of radiotherapy treatment planning is to find a treatment that will yield a high tumor control probability (TCP) with an acceptable normal tissue complication probability (NTCP). Yet most treatment planning today is not based upon optimization of TCPs and NTCPs, but rather upon meeting physical dose and volume constraints defined by the planner. It has been suggested that treatment planning evaluation and optimization would be more effective if they were biologically and not dose/volume based, and this is the claim debated in this month’s Point/Counterpoint. After a brief overview of biologically and DVH based treatment planning by the Moderator Colin Orton, Joseph Deasy (for biological planning) and Charles Mayo (against biological planning) will begin the debate. Some of the arguments in support of biological planning include: this will result in more effective dose distributions for many patients DVH-based measures of plan quality are known to have little predictive value there is little evidence that either D95 or D98 of the PTV is a good predictor of tumor control sufficient validated outcome prediction models are now becoming available and should be used to drive planning and optimization Some of the arguments against biological planning include: several decades of experience with DVH-based planning should not be discarded we do not know enough about the reliability and errors associated with biological models the radiotherapy community in general has little direct experience with side by side comparisons of DVH vs biological metrics and outcomes it is unlikely that a clinician would accept extremely cold regions in a CTV or hot regions in a PTV, despite having acceptable TCP values Learning Objectives: To understand dose/volume based treatment planning and its potential limitations To understand biological metrics such as EUD, TCP, and NTCP To understand biologically based treatment planning and its potential limitations

Free radicals in biology. Volume II

International Nuclear Information System (INIS)

Pryor, W.A.

1976-01-01

This volume continues the treatment of topics in free radical biology and free radical pathology from Volume I. In the first chapter, pyridinyl radicals, radicals which are models for those derived from NAD, are discussed. Pyridinyl radicals can be synthesized and isolated and directly studied in a number of chemical systems. The next chapter treats the role of glutathione in the cell. It is becoming even more apparent that this vital thiol controls a large number of important cellular functions. The GSH/GSSG balance has recently been implicated as a control for cellular development; this balance also may be important in relaying the effects of oxidants from one site to another in the body. The next chapter outlines the reactions of singlet oxygen; some of these involve free radicals and some do not. This reactive intermediate appears to be important both in photochemical smog and in cellular chemistry where singlet oxygen is produced by nonphotochemical processes. The production of free radicals from dry tissues, a controversial area with conflicting claims is reviewed. The next chapter outlines the current status of the studies of photochemical smog. The next two chapters treat specific reactive materials which are present in smog. The first discusses the chemistry of nitrogen oxides and ozone. The second chapter treats the chemistry of the peroxyacyl nitrites. These compounds, although present in only small concentration, are among the most toxic components of smog. The last two chapters treat radiation damage to proteins and radiation protection and radical reactions produced by radiation in nucleic acids

Ecological Footprint of Biological Resource Consumption in a Typical Area of the Green for Grain Project in Northwestern China

Directory of Open Access Journals (Sweden)

Jie Hu

2015-01-01

Full Text Available Following the implementation of the Green for Grain Project in 2000 in Guyuan, China, the decrease in cultivated land and subsequent increase in forest and grassland pose substantial challenges for the supply of biological products. Whether the current biologically productive land-use patterns in Guyuan satisfy the biological product requirements for local people is an urgent problem. In this study, the ecological footprints of biological resource consumption in Guyuan were calculated and analyzed based on the ‘City Hectare’ Ecological Footprint (EF Method. The EFs of different types of biological resource products consumed from different types of biologically productive land were then analyzed. In addition, the EFs of various biological resource products before and after the implementation of the Green for Grain Project (1998 and 2012 were assessed. The actual EF and bio-capacity (BC were compared, and differences in the EF and BC for different types of biologically productive lands before and after the project were analyzed. The results showed that the EF of Guyuan’s biological resource products was 0.65866 ha/cap, with an EF outflow and EF inflow of 0.2280 ha/cap and 0.0951 ha/cap, respectively. The per capita EF of Guyuan significantly decreased after the project, as did the ecological deficit. Whereas the cultivated land showed a deficit, grasslands were characterized by ecological surplus. The total EF of living resource consumption in Guyuan was 810,941 ha, and the total BC was 768,065 ha. In additional to current biological production areas, approximately 42,876 ha will be needed to satisfy the demands of Guyuan’s people. Cultivated land is the main type of biologically productive land that is needed.

Robins Air Force Base integrated resource assessment. Volume 3, Resource assessment

Energy Technology Data Exchange (ETDEWEB)

Sullivan, G.P.; Keller, J.M.; Stucky, D.J.; Wahlstrom, R.R.; Larson, L.L.

1993-10-01

The US Air Force Materiel Command (AFMC) has tasked the US Department of Energy (DOE) Federal Energy Management Program (FEMP), supported by the Pacific Northwest Laboratory (PNL), to identify, evaluate, and assist in acquiring all cost-effective energy projects at Robins Air Force Base (AFB). This is part of a model program that PNL is designing to support energy-use decisions in the federal sector. This report provides the results of the fossil fuel and electric energy resource opportunity (ERO) assessments performed by PNL at the AFMC Robins AFB facility located approximately 15 miles south of Macon, Georgia. It is a companion report to Volume 1, Executive Summary, and Volume 2, Baseline Detail. The results of the analyses of EROs are presented in 13 common energy end-use categories (e.g., boilers and furnaces, service hot water, and building lighting). A narrative-description of each ERO is provided, including information on the installed cost, energy and dollar savings; impacts on operation and maintenance (O&M); and, when applicable, a discussion of energy supply and demand, energy security, and environmental issues. A description of the evaluation methodologies and technical and cost assumptions is also provided for each ERO. Summary tables present the cost-effectiveness of energy end-use equipment before and after the implementation of each ERO and present the results of the life-cycle cost (LCC) analysis indicating the net present value (NPV) and savings to investment ratio (SIR) of each ERO.

Use and management of the natural resources of the Colombian Amazon rain forest: a biological approach

Directory of Open Access Journals (Sweden)

Angela Yaneth Landínez Torres

2013-12-01

Full Text Available This study analyzes the main features associated with biological use practices and management of forest resources in the Colombian Amazon. The theoretical cut proposal contrasts biological level, the forms of appropriation of forest resources in indigenous and urban contexts depending on the importance that such activity involves the establishment of management strategies biodiversity in Colombia. In this way, provides an integrative perspective that will address conflict situations considering environmental factors not only biological but cultural in various scenarios , to give sustenance to the decisions made and provide a reasonable treatment that enables the implementation of environmental regulation mechanisms in especially in areas such as strategic biological Colombian Amazon. Finally, reflect on the importance of facilitating the functional analysis of the connections and interrelationships of ecosystem components, including human communities, sketching involving both biological and social guidelines for sustainable use of biodiversity.

Prediction of resource volumes at untested locations using simple local prediction models

Science.gov (United States)

Attanasi, E.D.; Coburn, T.C.; Freeman, P.A.

2006-01-01

This paper shows how local spatial nonparametric prediction models can be applied to estimate volumes of recoverable gas resources at individual undrilled sites, at multiple sites on a regional scale, and to compute confidence bounds for regional volumes based on the distribution of those estimates. An approach that combines cross-validation, the jackknife, and bootstrap procedures is used to accomplish this task. Simulation experiments show that cross-validation can be applied beneficially to select an appropriate prediction model. The cross-validation procedure worked well for a wide range of different states of nature and levels of information. Jackknife procedures are used to compute individual prediction estimation errors at undrilled locations. The jackknife replicates also are used with a bootstrap resampling procedure to compute confidence bounds for the total volume. The method was applied to data (partitioned into a training set and target set) from the Devonian Antrim Shale continuous-type gas play in the Michigan Basin in Otsego County, Michigan. The analysis showed that the model estimate of total recoverable volumes at prediction sites is within 4 percent of the total observed volume. The model predictions also provide frequency distributions of the cell volumes at the production unit scale. Such distributions are the basis for subsequent economic analyses. ?? Springer Science+Business Media, LLC 2007.

World resources 1992-93

International Nuclear Information System (INIS)

Anon.

1992-01-01

The World Resources series is intended to meet the critical need for accessible, accurate information on some of the most pressing issues of our time. Wise management of natural resources and protection of the global environment are essential to achieve sustainable economic development and hence to alleviate poverty, improve the human condition, and preserve the biological systems on which all life depends. This volume has a special focus on sustainable development, in support of the upcoming 1992 United Nations Conference on Environment and Development (UNCED). Part 1 consists of four special chapters on sustainable development: an overview chapter and three case studies of what sustainable development might mean in industrial countries, low-income countries, and rapidly industrializing countries. Additional material pertinent to this topic is found throughout the volume. Part 2 continues the tradition of examining in each volume a particular region in more detail - in this case, an overview of the severe environmental and resource problems faced by Central Europe as that region makes a difficult transition to more democratic governments and more market-oriented economies. Part 3 reports on basic conditions and trends, key issues, major problems and efforts to resolve them, and recent developments in each of the major resource categories, from population and human development to energy to atmosphere and climate. Where data exist, the chapters give a 20-year perspective on trends in the physical environment - spanning the time between the first United Nations Conference on the Environment and UNCED. Supporting data, as well as the core data tables from the World Resources Data Base, are found in Part 4. Chapters have been processed separately for inclusion on the data base

Cold Spring Harbor symposia on quantitative biology: Volume 49, Recombination at the DNA level

International Nuclear Information System (INIS)

1984-01-01

This volume contains full papers prepared by the participants to the 1984 Cold Springs Harbor Symposia on Quantitative Biology. This year's theme is entitled Recombination at the DNA level. The volume consists of 93 articles grouped into subject areas entitled chromosome mechanics, yeast systems, mammalian homologous recombination, transposons, mu, plant transposons/T4 recombination, topoisomerase, resolvase and gyrase, Escherichia coli general recombination, RecA, repair, leukaryotic enzymes, integration and excision of bacteriophage, site-specific recombination, and recombination in vitro

Pesticides; resource recovery; hazardous substances and oil spill responses; waste disposal; biological effects

International Nuclear Information System (INIS)

Anon.

1991-01-01

In the category of pesticides this volume features close to sixty standard test method, practices, and guides for evaluating the properties and efficacy of pesticides and antimicrobial agents. Also covered are standards for hazardous substances, oil spell responses, waste disposal, and biological effects of these materials

BEDVH--A method for evaluating biologically effective dose volume histograms: Application to eye plaque brachytherapy implants

International Nuclear Information System (INIS)

Gagne, Nolan L.; Leonard, Kara L.; Huber, Kathryn E.; Mignano, John E.; Duker, Jay S.; Laver, Nora V.; Rivard, Mark J.

2012-01-01

Purpose: A method is introduced to examine the influence of implant duration T, radionuclide, and radiobiological parameters on the biologically effective dose (BED) throughout the entire volume of regions of interest for episcleral brachytherapy using available radionuclides. This method is employed to evaluate a particular eye plaque brachytherapy implant in a radiobiological context. Methods: A reference eye geometry and 16 mm COMS eye plaque loaded with 103 Pd, 125 I, or 131 Cs sources were examined with dose distributions accounting for plaque heterogeneities. For a standardized 7 day implant, doses to 90% of the tumor volume ( TUMOR D 90 ) and 10% of the organ at risk volumes ( OAR D 10 ) were calculated. The BED equation from Dale and Jones and published α/β and μ parameters were incorporated with dose volume histograms (DVHs) for various T values such as T = 7 days (i.e., TUMOR 7 BED 10 and OAR 7 BED 10 ). By calculating BED throughout the volumes, biologically effective dose volume histograms (BEDVHs) were developed for tumor and OARs. Influence of T, radionuclide choice, and radiobiological parameters on TUMOR BEDVH and OAR BEDVH were examined. The nominal dose was scaled for shorter implants to achieve biological equivalence. Results: TUMOR D 90 values were 102, 112, and 110 Gy for 103 Pd, 125 I, and 131 Cs, respectively. Corresponding TUMOR 7 BED 10 values were 124, 140, and 138 Gy, respectively. As T decreased from 7 to 0.01 days, the isobiologically effective prescription dose decreased by a factor of three. As expected, TUMOR 7 BEDVH did not significantly change as a function of radionuclide half-life but varied by 10% due to radionuclide dose distribution. Variations in reported radiobiological parameters caused TUMOR 7 BED 10 to deviate by up to 46%. Over the range of OAR α/β values, OAR 7 BED 10 varied by up to 41%, 3.1%, and 1.4% for the lens, optic nerve, and lacrimal gland, respectively. Conclusions: BEDVH permits evaluation of the

Remote sensing for environmental monitoring and resource management. Volume 2

International Nuclear Information System (INIS)

1992-01-01

The subject of this volume is remote sensing for environmental monitoring and resource management. This session is divided in eight parts. First part is on general topics, methodology and meteorology. Second part is on geology, environment and land cover. Third part is on disaster monitoring. Fourth part is on operational status of remote sensing. Fifth part is on coastal zones and inland waters. Sixth and seventh parts are on forestry and agriculture. Eighth part is on instrumentation and systems. (A.B.). refs., figs., tabs

Patrick Air Force Base integrated resource assessment. Volume 2, Baseline detail

Energy Technology Data Exchange (ETDEWEB)

Wahlstrom, R.R.; King, D.A.; Parker, S.A.; Sandusky, W.F.

1993-08-01

The US Air Force has tasked the Pacific Northwest Laboratory (PNL), in support of the US Department of Energy (DOE) Federal Energy Management Program (FEMP), to assess energy use at Patrick Air Force Base (AFB). The information obtained from this assessment will be used in identifying energy resource opportunities to reduce overall energy consumption on the base. The primary focus of this report is to assess the current baseline energy consumption at Patrick AFB. It is a comparison report to Volume 1, the Executive Summary, and Volume 3, the Resource Assessment. This assessment requires that information be obtained and characterized for buildings, utilities, energy sources, energy uses, and load profile information to be used to improve the characterization of energy use on the base. The characteristics of electricity, natural gas, and No. 2 fuel oil are analyzed for on-base facilities and housing. The assessment examines basic regional information used to determine energy-use intensity (EUI) values for Patrick AFB facilities by building, fuel type, and energy end use. It also provides a summary of electricity consumption from Florida Power and Light Company (FPL) metered data for 1985-1991. Load profile information obtained from FPL data is presented for the north and south substations for the four seasons of the year, including weekdays and weekends.

Geographic information system in marine biology: Way for sustainable utilization of living resources

Digital Repository Service at National Institute of Oceanography (India)

Chavan, V.S.; Sreepada, R.A.

Sustainable utilization of aquatic living resources needs accurate assessment. This stress the need for use of Geographic Information System (GIS). In the recent past interest has been generated for use of GIS in various areas of biological...

Biological intrusion barriers for large-volume waste-disposal sites

International Nuclear Information System (INIS)

Hakonson, T.E.; Cline, J.F.; Rickard, W.H.

1982-01-01

intrusion of plants and animals into shallow land burial sites with subsequent mobilization of toxic and radiotoxic materials has occured. Based on recent pathway modeling studies, such intrusions can contribute to the dose received by man. This paper describes past work on developing biological intrusion barrier systems for application to large volume waste site stabilization. State-of-the-art concepts employing rock and chemical barriers are discussed relative to long term serviceability and cost of application. The interaction of bio-intrusion barrier systems with other processes affecting trench cover stability are discussed to ensure that trench cover designs minimize the potential dose to man. 3 figures, 6 tables

Pembangunan Kebun Biologi Wamena*[establishment of Wamena Biological Gardens

OpenAIRE

Rahmansyah, M; Latupapua, HJD

2003-01-01

The richness of biological resources (biodiversity) in mountainous area of Papua is an asset that has to be preserved.Exploitation of natural resources often cause damage on those biological assets and as genetic resources.Care has to be taken to overcome the situation of biological degradation, and alternate steps had been shaped on ex-situ biological conservation. Wamena Biological Gardens, as an ex-situ biological conservation, has been established to keep the high mountain biological and ...

Complex Liver Resections for Colorectal Metastases: Are They Safe in the Low-Volume, Resource-Poor Caribbean Setting?

Directory of Open Access Journals (Sweden)

Shamir O. Cawich

2015-01-01

Full Text Available Introduction. Although many authorities suggest that major liver resections should only be carried out in high-volume specialized centres, many patients in the Caribbean do not have access to these health care systems. Presentation of a Case. A 50-year-old woman with a solitary colorectal metastasis invading the inferior vena cava underwent an extended left hepatectomy with caval resection and reconstruction. Several technical maneuvers were utilized that were suited to the resource-poor environment. Conclusion. We suggest that good outcomes can still be attained in the resource-poor, low-volume centres once dedicated and appropriately trained teams are available.

Evaluation of a fungal collection as certified reference material producer and as a biological resource center

Directory of Open Access Journals (Sweden)

Tatiana Forti

2016-06-01

Full Text Available Abstract Considering the absence of standards for culture collections and more specifically for biological resource centers in the world, in addition to the absence of certified biological material in Brazil, this study aimed to evaluate a Fungal Collection from Fiocruz, as a producer of certified reference material and as Biological Resource Center (BRC. For this evaluation, a checklist based on the requirements of ABNT ISO GUIA34:2012 correlated with the ABNT NBR ISO/IEC17025:2005, was designed and applied. Complementing the implementation of the checklist, an internal audit was performed. An evaluation of this Collection as a BRC was also conducted following the requirements of the NIT-DICLA-061, the Brazilian internal standard from Inmetro, based on ABNT NBR ISO/IEC 17025:2005, ABNT ISO GUIA 34:2012 and OECD Best Practice Guidelines for BRCs. This was the first time that the NIT DICLA-061 was applied in a culture collection during an internal audit. The assessments enabled the proposal for the adequacy of this Collection to assure the implementation of the management system for their future accreditation by Inmetro as a certified reference material producer as well as its future accreditation as a Biological Resource Center according to the NIT-DICLA-061.

Biological productivity and potential resources of the exclusive economic zone (EEZ) of India

Digital Repository Service at National Institute of Oceanography (India)

Goswami, S.C.

An assessment of the biological production and the potential fishery resources has been made based on the data collected over a period of 15 years (1976-1991). The entire Exclusive Economic Zone (EEZ), measuring 2.02 million km sup(2) was divided...

NEO Targets for Biological In Situ Resource Utilization

Science.gov (United States)

Grace, J. M.; Ernst, S. M.; Navarrete, J. U.; Gentry, D.

2014-12-01

We are investigating a mission architecture concept for low-cost pre-processing of materials on long synodic period asteroids using bioengineered microbes delivered by small spacecraft. Space exploration opportunities, particularly those requiring a human presence, are sharply constrained by the high cost of launching resources such as fuel, construction materials, oxygen, water, and foodstuffs. Near-Earth asteroids (NEAs) have been proposed for supporting a human space presence. However, the combination of high initial investment requirements, delayed potential return, and uncertainty in resource payoff currently prevents their effective utilization.Biomining is the process in which microorganisms perform useful material reduction, sequestration or separation. It is commonly used in terrestrial copper extraction. Compared to physical and chemical methods of extraction it is slow, but very low cost, thus rendering economical even very poor ores. These advantages are potentially extensible to asteroid in situ resource utilization (ISRU).One of the first limiting factors for the use of biology in these environments is temperature. A survey of NEA data was conducted to identify those NEAs whose projected interior temperatures remained within both potential (-5 - 100 ºC) and preferred (15 - 45 ºC) ranges for the minimum projected time per synodic period without exceeding 100 ºC at any point. Approximately 2800 of the 11000 NEAs (25%) are predicted to remain within the potential range for at least 90 days, and 120 (1%) in the preferred range.A second major factor is water availability and stability. We have evaluated a design for a small-spacecraft-based injector which forces low-temperature fluid into the NEA interior, creating potentially habitable microniches. The fluid contains microbes genetically engineered to accelerate the degradation rates of a desired fraction of the native resources, allowing for more efficient material extraction upon a subsequent

Automatic definition of targeted biological volumes for the radiotherapy applications

International Nuclear Information System (INIS)

Hatt, M.; Visvikis, D.; Cheze-Le-Rest, C.; Pradier, O.

2009-01-01

The proposed method: Fuzzy locally adaptive Bayesian (F.L.A.B.) showed its reliability and its precision on very complete collection of realistic simulated and real data. Its use in the context of radiotherapy allows to consider easily the studies implementation and scenari of dose painting or dose escalation, including in complex cases of heterogenous fixations. It is conceivable to apply F.L.A.B. on PET images with F.M.I.S.O. ( 18 F fluoro misonidazole) or F.L.T. (fluoro-L-thymidine) to complete the definition of the biological target volume. (N.C.)

ABOUT SYSTEM MAPPING OF BIOLOGICAL RESOURCES FOR SUBSTANTIATION OF ENVIRONMENTAL MANAGEMENT OF THE ADMINISTRATED UNIT ON THE EXAMPLE OF NOVOSIBIRSK REGION

Directory of Open Access Journals (Sweden)

O. N. Nikolaeva

2017-01-01

Full Text Available The article considers the issues of systematization, modeling and presentation of regional biological resources data. The problem of providing regional state authorities with actual biological resources data and an analysis tool has been stated. The necessity of complex analysis of heterogeneous biological resources data in connection with the landscape factors has been articulated. The system of biological resources’ cartographic models (BRCM is proposed as tools for the regional authorities to develop the BRCM for practical appliances. The goal and the target audience of the system are named. The principles of cartographic visualization of information in the BRCM are formulated. The main sources of biological resources data are listed. These sources include state cadastres, monitoring and statistics. The scales for regional and topical biological resources’ cartographic models are stated. These scales comprise two scale groups for depicting the region itself and its units of internal administrative division. The specifics of cartographic modeling and visualization of relief according to legal requirements to public cartographic data are described. Various options of presentation of biological resources’ cartographic models, such as digital maps, 3Dmodels and cartographic animation are described. Examples of maps and cartographic 3D-models of Novosibirsk Region forests are shown. The conclusion about practical challenges solved with BRCM has been made.

Environmental-Economic Accounts and Financial Resource Mobilisation for Implementation the Convention on Biological Diversity

OpenAIRE

Cesare Costantino; Emanuela Recchini

2015-01-01

At the Rio “Earth Summit” the Convention on Biological Diversity introduced a global commitment to conservation of biological diversity and sustainable use of its components. An implementation process is going on, based on a strategic plan, biodiversity targets and a strategy for mobilizing financial resources. According to target “2”, by 2020 national accounts should include monetary aggregates related to biodiversity. Environmental accounts can play an important role – together with other i...

Resources scarcity: Cause of potential conflicts

Directory of Open Access Journals (Sweden)

Beriša Hatidža A.

2016-01-01

Full Text Available Natural resources are a common good and the common wealth of each country. Their use, commercial applications and economic evaluation should be planned focused and targeted controlled. In a group of natural resources include: energy resources, water, food, land, mineral resources, biological resources and others. Given that the conditions of resource exploitation variable categories, it can be said that the volume of resources also variable. Abstracting growing problem of resources scarcity of vital importance to the existence in the world, this paper aims to try to shed light on the wider and comprehensive aspects of contemporary global problems in the scarcity of natural resources with a focus on the deficit of food, water and energenata. Search for answers to questions related to the scarcity of the basic needs of some of the world's population, civilizational confrontation about the energy pie, is a research and empirical contribution to the work, which is reflected in the effort to look at global challenges that mankind faces in the second decade of the 21st century.

Cape Canaveral Air Force Station integrated resource assessment. Volume 3, Resource assessment

Energy Technology Data Exchange (ETDEWEB)

Sandusky, W.F.; Eichman, C.J.; King, D.A.; McMordie, K.L.; Parker, S.A.; Shankle, S.A.; Wahlstrom, R.R.

1994-03-01

The U.S. Air Force (USAF) has tasked the Pacific Northwest Laboratory (PNL) in support of the U.S. Department of Energy (DOE) Federal Energy Management Program (FEMP), to identify, evaluate, and assist in acquiring all cost-effective energy projects at Cape Canaveral Air Force Station (AFS). Projects considered can be either in the form of energy management or energy conservation. The overall efforts of this task are based on a model program PNL is designing to support energy-use decisions in the federal sector. This report provides the results of the fossil fuel and electric energy resource opportunity (ERO) assessments performed by PNL at Cape Canaveral AFS, which is located approximately 10 miles north of Cocoa Beach, Florida. It is a companion report to Volume 1: Executive Summary and Volume 2: Baseline Detail. The results of the analyses of EROs are presented in 11 common energy end-use categories (e.g., boilers and furnaces, service hot water, and building lighting). A narrative description of each ERO is provided, including information on the installed cost, energy and dollar savings, impacts on operations and maintenance (O&M), and, when applicable, a discussion of energy supply and demand, energy security, and environmental issues. Descriptions of the evaluation methodologies and technical and cost assumptions are also provided for each ERO. Summary tables present the cost- effectiveness of energy end-use equipment before and after the implementation of each ERO and present the results of the life-cycle cost (LCC) analysis, indicating the net present value (NPV) and savings-to-investment ratio (SIR) of each ERO.

Evaluation of a fungal collection as certified reference material producer and as a biological resource center.

Science.gov (United States)

Forti, Tatiana; Souto, Aline da S S; do Nascimento, Carlos Roberto S; Nishikawa, Marilia M; Hubner, Marise T W; Sabagh, Fernanda P; Temporal, Rosane Maria; Rodrigues, Janaína M; da Silva, Manuela

2016-01-01

Considering the absence of standards for culture collections and more specifically for biological resource centers in the world, in addition to the absence of certified biological material in Brazil, this study aimed to evaluate a Fungal Collection from Fiocruz, as a producer of certified reference material and as Biological Resource Center (BRC). For this evaluation, a checklist based on the requirements of ABNT ISO GUIA34:2012 correlated with the ABNT NBR ISO/IEC17025:2005, was designed and applied. Complementing the implementation of the checklist, an internal audit was performed. An evaluation of this Collection as a BRC was also conducted following the requirements of the NIT-DICLA-061, the Brazilian internal standard from Inmetro, based on ABNT NBR ISO/IEC 17025:2005, ABNT ISO GUIA 34:2012 and OECD Best Practice Guidelines for BRCs. This was the first time that the NIT DICLA-061 was applied in a culture collection during an internal audit. The assessments enabled the proposal for the adequacy of this Collection to assure the implementation of the management system for their future accreditation by Inmetro as a certified reference material producer as well as its future accreditation as a Biological Resource Center according to the NIT-DICLA-061. Copyright © 2016 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

Vandenberg Air Force Base integrated resource assessment. Volume 3, Resource assessment

Energy Technology Data Exchange (ETDEWEB)

Daellenbach, K.K.; Dagle, J.E.; Dittmer, A.L.; Elliott, D.B.; Halverson, M.A.; Hickman, B.J.; Parker, G.B.; Richman, E.E.; Shankle, S.A.

1993-06-01

The US Air Force Space Command (SPACECOM) has tasked the Pacific Northwest Laboratory (PNL), as the lead laboratory supporting the US Department of Energy (DOE) Federal Energy Management Program (FEMP), to identify, evaluate, and assist in acquiring all cost-effective energy projects at Vandenberg Air Force Base (VAFB). This is part of a model program that PNL is designing to support energy-use decisions in the federal sector. This report provides the results of the fossil fuel and electric energy resource opportunity (ERO) assessments performed by PNL at the SPACECOM VAFB facility located approximately 50 miles northwest of Santa Barbara, California. It is a companion report to Volume 1, Executive Summary, and Volume 2, Baseline Detail. The results of the analysis of EROs are presented in ten common energy end-use categories (e.g., boilers and furnaces, service hot water, and building lighting). In addition, a case study of process loads at Space Launch Complex-4 (SLC-4) is included. A narrative description of each ERO is provided, including information on the installed cost, energy and dollar savings; impacts on operation and maintenance (O and M); and, when applicable, a discussion of energy supply and demand, energy security, and environmental issues. A description of the evaluation methodologies and technical and cost assumptions is also provided for each ERO. Summary tables present the cost-effectiveness of energy end-use equipment before and after the implementation of each ERO and present the results of the life-cycle cost (LCC) analysis indicating the net present value (NPV) and value index (VI) of each ERO. Finally, an appendix includes a summary of an economic analysis case study of the South Vandenberg Power Plant (SVPP) operating scenarios.

General-purpose computer networks and resource sharing in ERDA. Volume 3. Remote resource-sharing experience and findings

Energy Technology Data Exchange (ETDEWEB)

1977-07-15

The investigation focused on heterogeneous networks in which a variety of dissimilar computers and operating systems were interconnected nationwide. Homogeneous networks, such as MFE net and SACNET, were not considered since they could not be used for general purpose resource sharing. Issues of privacy and security are of concern in any network activity. However, consideration of privacy and security of sensitive data arise to a much lesser degree in unclassified scientific research than in areas involving personal or proprietary information. Therefore, the existing mechanisms at individual sites for protecting sensitive data were relied on, and no new protection mechanisms to prevent infringement of privacy and security were attempted. Further development of ERDA networking will need to incorporate additional mechanisms to prevent infringement of privacy. The investigation itself furnishes an excellent example of computational resource sharing through a heterogeneous network. More than twenty persons, representing seven ERDA computing sites, made extensive use of both ERDA and non-ERDA computers in coordinating, compiling, and formatting the data which constitute the bulk of this report. Volume 3 analyzes the benefits and barriers encountered in actual resource sharing experience, and provides case histories of typical applications.

Water Resources Data Ohio: Water year 1994. Volume 1, Ohio River Basin excluding Project Data

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-12-31

The Water Resources Division of the US Geological Survey (USGS) in cooperation with State agencies, obtains a large amount of data each water year (a water year is the 12-month period from October 1 through September 30 and is identified by the calendar year in which it ends) pertaining to the water resources of Ohio. These data, accumulated during many years, constitute a valuable data base for developing an improved understanding of the water resources of the State. To make these data readily available to interested parties outside the USGS, they are published annually in this report series entitled ``Water Resources Data--Ohio.`` This report (in two volumes) includes records on surface water and ground water in the State. Specifically, it contains: (1) Discharge records for streamflow-gaging stations, miscellaneous sites, and crest-stage stations; (2) stage and content records for streams, lakes, and reservoirs; (3) water-quality data for streamflow-gaging stations, wells, synoptic sites, and partial-record sit -aid (4) water-level data for observation wells. Locations of lake-and streamflow-gaging stations, water-quality stations, and observation wells for which data are presented in this volume are shown in figures 8a through 8b. The data in this report represent that part of the National Water Data System collected by the USGS and cooperating State and Federal agencies in Ohio. This series of annual reports for Ohio began with the 1961 water year with a report that contained only data relating to the quantities of surface water. For the 1964 water year, a similar report was introduced that contained only data relating to water quality. Beginning with the 1975 water year, the report was changed to present (in two or three volumes) data on quantities of surface water, quality of surface and ground water, and ground-water levels.

Resource Recovery from Wastewater by Biological Technologies: Opportunities, Challenges, and Prospects

Science.gov (United States)

Puyol, Daniel; Batstone, Damien J.; Hülsen, Tim; Astals, Sergi; Peces, Miriam; Krömer, Jens O.

2017-01-01

Limits in resource availability are driving a change in current societal production systems, changing the focus from residues treatment, such as wastewater treatment, toward resource recovery. Biotechnological processes offer an economic and versatile way to concentrate and transform resources from waste/wastewater into valuable products, which is a prerequisite for the technological development of a cradle-to-cradle bio-based economy. This review identifies emerging technologies that enable resource recovery across the wastewater treatment cycle. As such, bioenergy in the form of biohydrogen (by photo and dark fermentation processes) and biogas (during anaerobic digestion processes) have been classic targets, whereby, direct transformation of lipidic biomass into biodiesel also gained attention. This concept is similar to previous biofuel concepts, but more sustainable, as third generation biofuels and other resources can be produced from waste biomass. The production of high value biopolymers (e.g., for bioplastics manufacturing) from organic acids, hydrogen, and methane is another option for carbon recovery. The recovery of carbon and nutrients can be achieved by organic fertilizer production, or single cell protein generation (depending on the source) which may be utilized as feed, feed additives, next generation fertilizers, or even as probiotics. Additionlly, chemical oxidation-reduction and bioelectrochemical systems can recover inorganics or synthesize organic products beyond the natural microbial metabolism. Anticipating the next generation of wastewater treatment plants driven by biological recovery technologies, this review is focused on the generation and re-synthesis of energetic resources and key resources to be recycled as raw materials in a cradle-to-cradle economy concept. PMID:28111567

Space Biology and Medicine. Volume I; Space and Its Exploration

Science.gov (United States)

Nicogossian, Arnauld E.; Mohler, Stanley R.; Gazenko, Oleg G.; Grigoryev, Anatoliy I.

1993-01-01

and a path to our common future. But for humanity to embark on this path, we need to understand ourselves in a new environment. As such, an understanding of the biological consequences of and opportunities in space flight is essential. In this, the first volume of a joint U.S./Russian series on space biology and medicine, we describe the current status of our understanding of space and present general information that will prove useful when reading subsequent volumes. Since we are witnesses to the beginning of a new era of interplanetary travel, a significant portion of the first volume will concentrate on the physical and ecological conditions that exist in near and outer space, as well as heavenly bodies from the smallest ones to the giant planets and stars. While space exploration is a comparatively recent endeavor, its foundations were laid much more than 30 years ago, and its history has been an eventful one. In the first part of this volume, Rauschenbach, Sokolskiy, and Gurjian address the "Historical Aspects of Space Exploration" from its beginnings to a present-day view of the events of the space age. The nature of space itself and its features is the focus of the second section of the volume. In the first chapter of the part, "Stars and Interstellar Space," the origin and evolution of stars, and the nature of the portions of space most distant from Earth are described by Galeev and Marochnik. In Chapter 2, Pisarenko, Logachev, and Kurt in "The Sun and Interplanetary Space" bring us to the vicinity of our own solar system and provide a description and discussion of the nearest star and its influence on the space environment that our Earth and the other planets inhabit. In our solar system there are many fascinating objects, remnants of the formation of a rather ordinary star in a rather obscure portion of the galaxy. Historical accident has caused us to be much more curious (and knowledgeable) about "The Inner Planets of the Solar System" than about any of

Code of Conduct on Biosecurity for Biological Resource Centres: procedural implementation.

Science.gov (United States)

Rohde, Christine; Smith, David; Martin, Dunja; Fritze, Dagmar; Stalpers, Joost

2013-07-01

A globally applicable code of conduct specifically dedicated to biosecurity has been developed together with guidance for its procedural implementation. This is to address the regulations governing potential dual-use of biological materials, associated information and technologies, and reduce the potential for their malicious use. Scientists researching and exchanging micro-organisms have a responsibility to prevent misuse of the inherently dangerous ones, that is, those possessing characters such as pathogenicity or toxin production. The code of conduct presented here is based on best practice principles for scientists and their institutions working with biological resources with a specific focus on micro-organisms. It aims to raise awareness of regulatory needs and to protect researchers, their facilities and stakeholders. It reflects global activities in this area in response to legislation such as that in the USA, the PATRIOT Act of 2001, Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act of 2001; the Anti-Terrorism Crime and Security Act 2001 and subsequent amendments in the UK; the EU Dual-Use Regulation; and the recommendations of the Organization for Economic Co-operation and Development (OECD), under their Biological Resource Centre (BRC) Initiative at the beginning of the millennium (OECD, 2001). Two project consortia with international partners came together with experts in the field to draw up a Code of Conduct on Biosecurity for BRCs to ensure that culture collections and microbiologists in general worked in a way that met the requirements of such legislation. A BRC is the modern day culture collection that adds value to its holdings and implements common best practice in the collection and supply of strains for research and development. This code of conduct specifically addresses the work of public service culture collections and describes the issues of importance and the controls or

Access to genetic resources in indigenous peoples and the Convention on Biological Diversity

Directory of Open Access Journals (Sweden)

Diana Rocío Bernal Camargo

2013-06-01

Full Text Available After the Convention on Biological Diversity a deepening debate is taking place concerning the protection of genetic resources and traditional knowledge of indigenous peoples, which involves a discussion about the application of biotechnology and its impact on the protection of life and environment, and an analysis of the participation of these in the process of developing strategies to protect their resources and traditional knowledge, which gives rise to legal pluralism from the development of the different Conferences of the Parties, which today allows for a more comprehensive regulatory framework and a possibility of its strengthening.

Best practices for the use and exchange of invertebrate biological control genetic resources relevant for food and agriculture

NARCIS (Netherlands)

Mason, P.G.; Cock, M.J.W.; Barratt, B.I.P.; Klapwijk, J.N.; Lenteren, van J.C.; Brodeur, J.; Hoelmer, K.A.; Heimpel, G.E.

2018-01-01

The Nagoya Protocol is a supplementary agreement to the Convention on Biological Diversity that provides a framework for the effective implementation of the fair and equitable sharing of benefits arising out of the utilization of genetic resources, including invertebrate biological control agents.

IntegromeDB: an integrated system and biological search engine.

Science.gov (United States)

Baitaluk, Michael; Kozhenkov, Sergey; Dubinina, Yulia; Ponomarenko, Julia

2012-01-19

With the growth of biological data in volume and heterogeneity, web search engines become key tools for researchers. However, general-purpose search engines are not specialized for the search of biological data. Here, we present an approach at developing a biological web search engine based on the Semantic Web technologies and demonstrate its implementation for retrieving gene- and protein-centered knowledge. The engine is available at http://www.integromedb.org. The IntegromeDB search engine allows scanning data on gene regulation, gene expression, protein-protein interactions, pathways, metagenomics, mutations, diseases, and other gene- and protein-related data that are automatically retrieved from publicly available databases and web pages using biological ontologies. To perfect the resource design and usability, we welcome and encourage community feedback.

Currently Situation, Some Cases and Implications of the Legislation on Access and Benefit-sharing to Biologi cal Genetic Resource in Australia

Directory of Open Access Journals (Sweden)

LI Yi-ding

2017-01-01

Full Text Available Australia is one of the most abundant in biodiversity country of the global which located in Oceanian and became a signatory coun try of the Convention on Biodiversity, International Treaty on Plant Genetic Resource for Food and Agriculture, Convention on International Trade in Endangered Species. This country stipulated the Environmental Protection and Biodiversity Conservation Act(EPBC, 1999 and Environmental Protection and Biodiversity Conservation Regulations, 2002. Queensland and the North Territory passed the Bio-discovery Act in 2004 and Biological Resource Act in 2006 separately. This paper firstly focus on current situation, characteristic of the legislation on ac cess and benefit-sharing to biological resource in the commonwealth and local place in Australia and then collected and analyzed the typical case of access and benefit-sharing in this country that could bring some experience to China in this field. The conclusion of this paper is that China should stipulated the specific legislation on access and benefit-sharing to biological genetic resource as like the Environmental Protection and Biodiversity Conservation Act(EPBC, 1999 and establish the rule of procedure related to the access and benefit-sharing as like the Environmental Protection and Biodiversity Conservation Regulations, 2002, Bio-discovery Act in 2004, Queensland and the Biological Resource Act in 2006, the North Territory.

Form and function: Perspectives on structural biology and resources for the future

International Nuclear Information System (INIS)

Vaughan, D.

1990-12-01

The purpose of this study is largely to explore and expand on the thesis that biological structures and their functions are suited to. Form indeed follows function and if we are to understand the workings of a living system, with all that such an understanding promises, we must first seek to describe the structure of its parts. Descriptions of a few achievements of structural biology lay the groundwork, but the substance of this booklet is a discussion of important questions yet unanswered and opportunities just beyond our grasp. The concluding pages then outline a course of action in which the Department of Energy would exercise its responsibility to develop the major resources needed to extend our reach and to answer some of those unanswered questions. 22 figs

Form and function: Perspectives on structural biology and resources for the future

Energy Technology Data Exchange (ETDEWEB)

Vaughan, D. (ed.)

1990-12-01

The purpose of this study is largely to explore and expand on the thesis that biological structures and their functions are suited to. Form indeed follows function and if we are to understand the workings of a living system, with all that such an understanding promises, we must first seek to describe the structure of its parts. Descriptions of a few achievements of structural biology lay the groundwork, but the substance of this booklet is a discussion of important questions yet unanswered and opportunities just beyond our grasp. The concluding pages then outline a course of action in which the Department of Energy would exercise its responsibility to develop the major resources needed to extend our reach and to answer some of those unanswered questions. 22 figs.

Online Biodiversity Resources - Principles for Usability

Directory of Open Access Journals (Sweden)

Sophie Neale

2007-01-01

Full Text Available Online biodiversity portals and databases enabling access to large volumes of biological information represent a potentially extensive set of resources for a variety of user groups. However, in order for these resources to live up to their promise they need to be both useful and easy to use. We discuss a number of principles for designing systems for usability, examine how these have been applied to the development of online biodiversity resources and compare this with a portal project developed by the Astrophysics community. We highlight a lack of user involvement and formalised requirements analysis by biodiversity projects resulting in a poor understanding of both the users and their tasks. We suggest a change in the way large biodiversity portal projects are structured, that is by providing infrastructure and supporting user groups developing individual interfaces.

Maintenance resources optimization applied to a manufacturing system

International Nuclear Information System (INIS)

Fiori de Castro, Helio; Lucchesi Cavalca, Katia

2006-01-01

This paper presents an availability optimization of an engineering system assembled in a series configuration, with redundancy of units and corrective maintenance resources as optimization parameters. The aim is to reach maximum availability, considering as constraints installation and corrective maintenance costs, weight and volume. The optimization method uses a Genetic Algorithm based on biological concepts of species evolution. It is a robust method, as it does not converge to a local optimum. It does not require the use of differential calculus, thus facilitating computational implementation. Results indicate that the methodology is suitable to solve a wide range of engineering design problems involving allocation of redundancies and maintenance resources

Wadter Resources Data Ohio: Water year 1994. Volume 2, St. Lawrence River Basin and Statewide Project Data

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-12-31

The Water Resources Division of the US Geological Survey (USGS), in cooperation with State agencies, obtains a large amount of data each water year (a water year is the 12-month period from October 1 through September 30 and is identified by the calendar year in which it ends) pertaining to the water resources of Ohio. These data, accumulated during many years, constitute a valuable data base for developing an improved understanding of the water resources of the State. To make these data readily available to interested parties outside the USGS, they are published annually in this report series entitled ``Water Resources Data--Ohio.`` This report (in two volumes) includes records on surface water and ground water in the State. Specifically, it contains: (1) Discharge records for streamflow-gaging stations, miscellaneous sites, and crest-stage stations; (2) stage and content records for streams, lakes, and reservoirs; (3) water-quality data for streamflow-gaging stations, wells, synaptic sites, and partial-record sites; and (4) water-level data for observation wells. Locations of lake- and streamflow-gaging stations, water-quality stations, and observation wells for which data are presented in this volume are shown in figures ga through 8b. The data in this report represent that part of the National Water Data System collected by the USGS and cooperating State and Federal agencies in Ohio. This series of annual reports for Ohio began with the 1961 water year with a report that contained only data relating to the quantities of surface water. For the 1964 water year, a similar report was introduced that contained only data relating to water quality. Beginning with the 1975 water year, the report was changed to present (in two to three volumes) data on quantities of surface water, quality of surface and ground water, and ground-water levels.

Planning manual for energy resource development on Indian lands. Volume IV. The environment

Energy Technology Data Exchange (ETDEWEB)

1978-03-01

Many Indian tribes own rich deposits of very valuable energy resources. Existing and proposed uses of these tribal resources range from limited development of small oil and gas fields to large-scale extraction and conversion of coal, uranium, and oil shale. The adverse environmental impacts of such projects may create a conflict between a tribe's environmental policies and its economic, employment, and other long-term goals. The purpose of this volume is to provide tribal decision makers with reference documents on the mechanisms that are available to resolve such conflicts. This report focuses on the role of existing environmental laws in enabling tribes to achieve the needed balance among its objectives. Over a dozen major Federal statutes have been enacted to achieve this purpose. One law, the National Environmental Policy Act (NEPA), provides procedures to ensure that environmental factors are included in the Federal decision-making process. Numerous other laws, such as the Clean Air Act, have been enacted to prevent or control any negative environmental impacts of actual projects. This volume documents the key provisions of the laws and regulations, and discusses their effectiveness in meeting total needs. Also, tribal options to strengthen these mechanisms are highlighted. Sections II and III report on the role of NEPA in tribal development decisions. Section IV reviews those laws and regulations that control project operations.

Assessing the impacts of climate change on natural resource systems

Energy Technology Data Exchange (ETDEWEB)

Frederick, K.D.; Rosenberg, N.J. [eds.

1994-11-30

This volume is a collection of papers addressing the theme of potential impacts of climatic change. Papers are entitled Integrated Assessments of the Impacts of Climatic Change on Natural Resources: An Introductory Editorial; Framework for Integrated Assessments of Global Warming Impacts; Modeling Land Use and Cover as Part of Global Environmental Change; Assessing Impacts of Climatic Change on Forests: The State of Biological Modeling; Integrating Climatic Change and Forests: Economic and Ecological Assessments; Environmental Change in Grasslands: Assessment using Models; Assessing the Socio-economic Impacts of Climatic Change on Grazinglands; Modeling the Effects of Climatic Change on Water Resources- A Review; Assessing the Socioeconomic Consequences of Climate Change on Water Resources; and Conclusions, Remaining Issues, and Next Steps.

The Use of Didactic Resources as a Strategy in Sciences and Biology Teaching

Directory of Open Access Journals (Sweden)

Mario Marcos Lopes

2013-06-01

Full Text Available The teaching of Science and Biology at school is recent, and has been practiced according to the different educational proposals, that have been developed along the last decades. The LDB (Lei nº 9.394, December, 20, 1996 proposes a pedagogical project that goes beyond the blackboard, chalk and teacher's talk in order to better prepare the students for the challenges of the labor market. Thus, this paper aims at contributing to the discussion on the teaching practice and teaching resources that can help the teaching and learning process, especially in the disciplines of Science and Biology. Based on a qualitative approach, this research aims at contributing to the construction of new knowledge that can be generated from a careful and critical look at the documentary sources. Finally, the great challenge of the educator is to make the teaching of Science and Biology pleasurable and exciting, being able to develop in students the scientific knowledge and the taste for these school subjects.

Fusion of biological membranes

Indian Academy of Sciences (India)

Home; Journals; Pramana – Journal of Physics; Volume 64; Issue 6. Fusion of biological membranes. K Katsov M Müller M Schick. Invited Talks:- Topic 11. Biologically motivated problems (protein-folding models, dynamics at the scale of the cell; biological networks, evolution models, etc.) Volume 64 Issue 6 June 2005 pp ...

Water Resources Data. Ohio - Water Year 1992. Volume 1. Ohio River Basin excluding project data

Energy Technology Data Exchange (ETDEWEB)

H.L. Shindel; J.H. Klingler; J.P. Mangus; L.E. Trimble

1993-03-01

Water-resources data for the 1992 water year for Ohio consist of records of stage, discharge, and water quality of streams; stage and contents of lakes and reservoirs; and water levels and water quality of ground-water wells. This report, in two volumes, contains records for water discharge at 121 gaging stations, 336 wells, and 72 partial-record sites; and water levels at 312 observation wells. Also included are data from miscellaneous sites. Additional water data were collected at various sites not involved in the systematic data-collection program and are published as miscellaneous measurements and analyses. These data represent that part of the National Water Data System collected by the US Geological Survey and cooperating State and Federal agencies in Ohio. Volume 1 covers the central and southern parts of Ohio, emphasizing the Ohio River Basin. (See Order Number DE95010451 for Volume 2 covering the northern part of Ohio.)

Technical procedures for water resources: Volume 4, Deaf Smith County site, Texas: Environmental Field Program: Final draft

International Nuclear Information System (INIS)

1987-08-01

This volume contains Technical Procedures pursuant to the water Resources Site Study Plan: including Collection, Preservation, and Shipment of Ground-Water Samples; Inventory Current Water Use and Estimating Projected Water Use; Estimation of Precipitation Depth, Duration, Frequence; Estimation of Probable Maximum Precipitation; Calculation of Floodplains

Water resources data, Ohio: Water year 1991. Volume 2, St. Lawrence River Basin: Statewide project data

Energy Technology Data Exchange (ETDEWEB)

Shindel, H.L.; Klingler, J.H.; Mangus, J.P.; Trimble, L.E.

1992-03-01

The Water Resources Division of the US Geological Survey (USGS), in cooperation with State agencies, obtains a large amount of data pertaining to the water resources of Ohio each water year. These data, accumulated during many years, constitute a valuable data base for developing an improved understanding of the water resources of the State. To make these data readily available to interested parties outside the USGS, the data are published annually in this report series entitled ``Water Resources Data--Ohio.`` This report (in two volumes) includes records on surface water and ground water in the State. Specifically, it contains: (1) Discharge records for 131 streamflow-gaging stations, 95 miscellaneous sites; (2) stage and content records for 5 streams, lakes, and reservoirs; (3) water-quality for 40 streamflow-gaging stations, 378 wells, and 74 partial-record sites; and (4) water levels for 431 observation wells.

Advances in radiation biology: Relative radiation sensitivities of human organ systems. Volume 12

International Nuclear Information System (INIS)

Lett, J.T.; Altman, K.I.; Ehmann, U.K.; Cox, A.B.

1987-01-01

This volume is a thematically focused issue of Advances in Radiation Biology. The topic surveyed is relative radiosensitivity of human organ systems. Topics considered include relative radiosensitivities of the thymus, spleen, and lymphohemopoietic systems; relative radiosensitivities of the small and large intestine; relative rediosensitivities of the oral cavity, larynx, pharynx, and esophagus; relative radiation sensitivity of the integumentary system; dose response of the epidermal; microvascular, and dermal populations; relative radiosensitivity of the human lung; relative radiosensitivity of fetal tissues; and tolerance of the central and peripheral nervous system to therapeutic irradiation

Advances in radiation biology: Relative radiation sensitivities of human organ systems. Volume 12

Energy Technology Data Exchange (ETDEWEB)

Lett, J.T.; Altman, K.I.; Ehmann, U.K.; Cox, A.B.

1987-01-01

This volume is a thematically focused issue of Advances in Radiation Biology. The topic surveyed is relative radiosensitivity of human organ systems. Topics considered include relative radiosensitivities of the thymus, spleen, and lymphohemopoietic systems; relative radiosensitivities of the small and large intestine; relative rediosensitivities of the oral cavity, larynx, pharynx, and esophagus; relative radiation sensitivity of the integumentary system; dose response of the epidermal; microvascular, and dermal populations; relative radiosensitivity of the human lung; relative radiosensitivity of fetal tissues; and tolerance of the central and peripheral nervous system to therapeutic irradiation.

Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse.

Science.gov (United States)

Eppig, Janan T

2017-07-01

The Mouse Genome Informatics (MGI) Resource supports basic, translational, and computational research by providing high-quality, integrated data on the genetics, genomics, and biology of the laboratory mouse. MGI serves a strategic role for the scientific community in facilitating biomedical, experimental, and computational studies investigating the genetics and processes of diseases and enabling the development and testing of new disease models and therapeutic interventions. This review describes the nexus of the body of growing genetic and biological data and the advances in computer technology in the late 1980s, including the World Wide Web, that together launched the beginnings of MGI. MGI develops and maintains a gold-standard resource that reflects the current state of knowledge, provides semantic and contextual data integration that fosters hypothesis testing, continually develops new and improved tools for searching and analysis, and partners with the scientific community to assure research data needs are met. Here we describe one slice of MGI relating to the development of community-wide large-scale mutagenesis and phenotyping projects and introduce ways to access and use these MGI data. References and links to additional MGI aspects are provided. © The Author 2017. Published by Oxford University Press.

Will the Convention on Biological Diversity put an end to biological control?

NARCIS (Netherlands)

Lenteren, van J.C.; Cock, M.J.W.; Brodeur, J.; Barratt, B.I.P.; Bigler, F.; Bolckmans, K.; Haas, F.; Mason, P.G.; Parra, J.R.P.

2011-01-01

Will the Convention on Biological Diversity put an end to biological control? Under the Convention on Biological Diversity countries have sovereign rights over their genetic resources. Agreements governing the access to these resources and the sharing of the benefits arising from their use need to

Evaluation and Ranking of Geothermal Resources for Electrical Generation or Electrical Offset in Idaho, Montana, Oregon and Washington. Volume II.

Energy Technology Data Exchange (ETDEWEB)

Bloomquist, R. Gordon

1985-06-01

This volume contains appendices on: (1) resource assessment - electrical generation computer results; (2) resource assessment summary - direct use computer results; (3) electrical generation (high temperature) resource assessment computer program listing; (4) direct utilization (low temperature) resource assessment computer program listing; (5) electrical generation computer program CENTPLANT and related documentation; (6) electrical generation computer program WELLHEAD and related documentation; (7) direct utilization computer program HEATPLAN and related documentation; (8) electrical generation ranking computer program GEORANK and related documentation; (9) direct utilization ranking computer program GEORANK and related documentation; and (10) life cycle cost analysis computer program and related documentation. (ACR)

Technical procedures for water resources, Deaf Smith County site, Texas: Volume 1: Environmental Field Program: Final draft

International Nuclear Information System (INIS)

1987-08-01

This volume contains Technical Procedures pursuant to the Water Resources Site Study Plan including, determination of basin topographic characteristics, determination of channel and playa lake characteristics, operation of a stream gaging station, operation of a playa lake stage gaging system, and processing of data from a playa lake stage gaging system

Automatic definition of targeted biological volumes for the radiotherapy applications; Definition automatique des volumes biologiques cibles pour les applications de radiotherapie

Energy Technology Data Exchange (ETDEWEB)

Hatt, M.; Visvikis, D. [LaTIM, U650 Inserm, 29 - Brest (France); Cheze-Le-Rest, C. [Service de medecine nucleaire, 29 - Brest (France); Pradier, O. [Service de radiotherapie, 29 - Brest (France)

2009-10-15

The proposed method: Fuzzy locally adaptive Bayesian (F.L.A.B.) showed its reliability and its precision on very complete collection of realistic simulated and real data. Its use in the context of radiotherapy allows to consider easily the studies implementation and scenari of dose painting or dose escalation, including in complex cases of heterogenous fixations. It is conceivable to apply F.L.A.B. on PET images with F.M.I.S.O. ({sup 18}F fluoro misonidazole) or F.L.T. (fluoro-L-thymidine) to complete the definition of the biological target volume. (N.C.)

Impact of adherence to biological agents on health care resource utilization for patients over the age of 65 years with rheumatoid arthritis

Directory of Open Access Journals (Sweden)

Lathia U

2017-07-01

Full Text Available Urja Lathia, Emmanuel M Ewara, Francois Nantel Janssen Inc., Toronto, ON, Canada Objective: Poor adherence to therapy increases the patient and societal burden and complexity of chronic diseases such as rheumatoid arthritis (RA. In the past 15 years, biologic disease-modifying anti-rheumatic drugs (DMARDs have revolutionized the treatment of RA. However, little data are available on the impact of adherence to biologics on health care resources. The objective of the study was to determine the long-term health care resource utilization patterns of RA patients who were adherent to biologic DMARD therapy compared to RA patients who were non-adherent to biologic DMARD therapy in an Ontario population and to determine factors influencing adherence. Methods: Patients were identified from the Ontario RA Database that contains all RA patients in Ontario, Canada, identified since 1991. The study population included RA patients, aged 65+ years, with a prescription for a biologic DMARD between 2003 and 2013. Exclusion criteria included diagnosis of inflammatory bowel disease, psoriatic arthritis or psoriasis in the 5 years prior to the index date and discontinuation of biologic DMARD, defined as no subsequent prescription during the 12 months after the index date. Adherence was defined as a medication possession ratio of ≥0.8 measured as the proportion of days for which a patient had biologic treatment(s over a defined follow-up period. Adherent patients were matched to non-adherent patients by propensity score matching. Results: A total of 4,666 RA patients were identified, of whom 2,749 were deemed adherent and 1,917 non-adherent. The age (standard deviation was 69.9 (5.46 years and 75% were female. Relative rates for resource use (physician visits, emergency visits, hospitalization, home care and rehabilitation for the matched cohort were significantly lower (P<0.0001 in adherent patients. Non-adherent patients’ use of oral prednisone (67% was

'DRF-G - Grenoble Department of Fundamental Research. Activity report 1985, Nr 20. Volume II: 'Chemical Physics' 'Biology'

International Nuclear Information System (INIS)

1983-01-01

This volume contains synthetic reports of researches performed in chemistry, in the field of biological and medical applications of nuclear magnetic resonance, and in biology during the 1981-1983 period or only during 1983. As far as chemistry is concerned, the following topics have been addressed: conducting organic polymers, organic and analytic electrochemistry, coordination chemistry, molecular dynamics, vegetal macromolecules, nucleic acids. As far as biology is concerned, the following topics have been addressed: systems associated with membranes, metalloproteins, cell biology and differentiation, immuno-chemistry, haematology, vegetal physiology, structural studies of proteins. Staff lists of researchers are provided for chemistry laboratories and biology laboratories, as well a list of publications

Forest biological diversity interactions with resource utilization

Science.gov (United States)

S.T. Mok

1992-01-01

The most important forest resources of the Asia-Pacific region are the highly diverse rain forests. Utilization of the resource is a natural and inevitable consequence of the region's socio-economic development. The sustainable management and development of forest resources in the region can be achieved by implementing conservational forestry, which is based on...

Population Genetic Structure of Glycyrrhiza inflata B. (Fabaceae) Is Shaped by Habitat Fragmentation, Water Resources and Biological Characteristics.

Science.gov (United States)

Yang, Lulu; Chen, Jianjun; Hu, Weiming; Yang, Tianshun; Zhang, Yanjun; Yukiyoshi, Tamura; Zhou, Yanyang; Wang, Ying

2016-01-01

Habitat fragmentation, water resources and biological characteristics are important factors that shape the genetic structure and geographical distribution of desert plants. Analysis of the relationships between these factors and population genetic variation should help to determine the evolutionary potential and conservation strategies for genetic resources for desert plant populations. As a traditional Chinese herb, Glycyrrhiza inflata B. (Fabaceae) is restricted to the fragmented desert habitat in China and has undergone a dramatic decline due to long-term over-excavation. Determining the genetic structure of the G. inflata population and identifying a core collection could help with the development of strategies to conserve this species. We investigated the genetic variation of 25 G. inflata populations based on microsatellite markers. A high level of population genetic divergence (FST = 0.257), population bottlenecks, reduced gene flow and moderate genetic variation (HE = 0.383) were detected. The genetic distances between the populations significantly correlated with the geographical distances, and this suggests that habitat fragmentation has driven a special genetic structure of G. inflata in China through isolation by distance. STRUCTURE analysis showed that G. inflata populations were structured into three clusters and that the populations belonged to multiple water systems, which suggests that water resources were related to the genetic structure of G. inflata. In addition, the biological characteristics of the perennial species G. inflata, such as its long-lived seeds, asexual reproduction, and oasis ecology, may be related to its resistance to habitat fragmentation. A core collection of G. inflata, that included 57 accessions was further identified, which captured the main allelic diversity of G. inflata. Recent habitat fragmentation has accelerated genetic divergence. The population genetic structure of G. inflata has been shaped by habitat

National Uranium Resource Evaluation. Volume 1. Summary of the geology and uranium potential of Precambrian conglomerates in southeastern Wyoming

Energy Technology Data Exchange (ETDEWEB)

Karlstrom, K.E.; Houston, R.S.; Flurkey, A.J.; Coolidge, C.M.; Kratochvil, A.L.; Sever, C.K.

1981-02-01

A series of uranium-, thorium-, and gold-bearing conglomerates in Late Archean and Early Proterozoic metasedimentary rocks have been discovered in southern Wyoming. The mineral deposits were found by applying the time and strata bound model for the origin of uranium-bearing quartz-pebble conglomerates to favorable rock types within a geologic terrane known from prior regional mapping. No mineral deposits have been discovered that are of current (1981) economic interest, but preliminary resource estimates indicate that over 3418 tons of uranium and over 1996 tons of thorium are present in the Medicine Bow Mountains and that over 440 tons of uranium and 6350 tons of thorium are present in Sierra Madre. Sampling has been inadequate to determine gold resources. High grade uranium deposits have not been detected by work to date but local beds of uranium-bearing conglomerate contain as much as 1380 ppM uranium over a thickness of 0.65 meters. This project has involved geologic mapping at scales from 1/6000 to 1/50,000 detailed sampling, and the evaluation of 48 diamond drill holes, but the area is too large to fully establish the economic potential with the present information. This first volume summarizes the geologic setting and geologic and geochemical characteristics of the uranium-bearing conglomerates. Volume 2 contains supporting geochemical data, lithologic logs from 48 drill holes in Precambrian rocks, and drill site geologic maps and cross-sections from most of the holes. Volume 3 is a geostatistical resource estimate of uranium and thorium in quartz-pebble conglomerates.

National Uranium Resource Evaluation. Volume 1. Summary of the geology and uranium potential of Precambrian conglomerates in southeastern Wyoming

International Nuclear Information System (INIS)

Karlstrom, K.E.; Houston, R.S.; Flurkey, A.J.; Coolidge, C.M.; Kratochvil, A.L.; Sever, C.K.

1981-02-01

A series of uranium-, thorium-, and gold-bearing conglomerates in Late Archean and Early Proterozoic metasedimentary rocks have been discovered in southern Wyoming. The mineral deposits were found by applying the time and strata bound model for the origin of uranium-bearing quartz-pebble conglomerates to favorable rock types within a geologic terrane known from prior regional mapping. No mineral deposits have been discovered that are of current (1981) economic interest, but preliminary resource estimates indicate that over 3418 tons of uranium and over 1996 tons of thorium are present in the Medicine Bow Mountains and that over 440 tons of uranium and 6350 tons of thorium are present in Sierra Madre. Sampling has been inadequate to determine gold resources. High grade uranium deposits have not been detected by work to date but local beds of uranium-bearing conglomerate contain as much as 1380 ppM uranium over a thickness of 0.65 meters. This project has involved geologic mapping at scales from 1/6000 to 1/50,000 detailed sampling, and the evaluation of 48 diamond drill holes, but the area is too large to fully establish the economic potential with the present information. This first volume summarizes the geologic setting and geologic and geochemical characteristics of the uranium-bearing conglomerates. Volume 2 contains supporting geochemical data, lithologic logs from 48 drill holes in Precambrian rocks, and drill site geologic maps and cross-sections from most of the holes. Volume 3 is a geostatistical resource estimate of uranium and thorium in quartz-pebble conglomerates

Frontiers in mathematical biology

CERN Document Server

1994-01-01

Volume 100, which is the final volume of the LNBM series serves to commemorate the acievements in two decades of this influential collection of books in mathematical biology. The contributions, by the leading mathematical biologists, survey the state of the art in the subject, and offer speculative, philosophical and critical analyses of the key issues confronting the field. The papers address fundamental issues in cell and molecular biology, organismal biology, evolutionary biology, population ecology, community and ecosystem ecology, and applied biology, plus the explicit and implicit mathematical challenges. Cross-cuttting issues involve the problem of variation among units in nonlinear systems, and the related problems of the interactions among phenomena across scales of space, time and organizational complexity.

Potential use of geothermal resources in the Snake River Basin: an environmental overview. Volume II. Annotated bibliography

Energy Technology Data Exchange (ETDEWEB)

Spencer, S.G.; Russell, B.F.; Sullivan, J.F. (eds.)

1979-09-01

This volume is a partially annotated bibliography of reference materials pertaining to the seven KGRA's. The bibliography is divided into sections by program element as follows: terrestrial ecology, aquatic ecology, heritage resources, socioeconomics and demography, geology, geothermal, soils, hydrology and water quality, seismicity, and subsidence. Cross-referencing is available for those references which are applicable to specific KGRA's. (MHR)

Water resource planning and water quality in the Riu Cixerri Basin (Southern Sardinia)

International Nuclear Information System (INIS)

Coni, M.; Ferralis, M; Madonia, P.; Sechi, C.; Verde, C.

2000-01-01

Present paper deals with a hydrogeological and biological study of the Riu Cixerri watershed (Southern Sardinia), carried out in order to evaluate volumes and quality of surface waters. Variables of hydrogeological balance have been derived by the use of a G.I.S. based method. The obtained results underline the low reliability of data used for past water resource planning and the good self purification capability of the Cixerri river [it

Feasibility of disposal of high-level radioactive waste into the seabed. Volume 6: Deep-sea biology, biological processes and radiobiology

International Nuclear Information System (INIS)

Pentreath, R.J.; Hargrave, B.T.; Roe, H.S.J.; Sibuet, M.

1988-01-01

One of the options suggested for disposal of high-level radioactive waste resulting from the generation of nuclear power is burial beneath the deep ocean floor in geologically stable sediment formations which have no economic value. The 8-volume series provides an assessment of the technical feasibility and radiological safety of this disposal concept based on the results obtained by ten years of co-operation and information exchange among the Member countries participating in the NEA Seabed Working Group. This report summarizes the biological description of selected sites, the means by which radionuclides could result in human exposure via seafood pathways, and the doses likely to be received by, and effects on, the deep-sea fauna

Local wisdom of Ngata Toro community in utilizing forest resources as a learning source of biology

Science.gov (United States)

Yuliana, Sriyati, Siti; Sanjaya, Yayan

2017-08-01

Indonesian society is a pluralistic society with different cultures and local potencies that exist in each region. Some of local community still adherethe tradition from generation to generation in managing natural resources wisely. The application of the values of local wisdom is necessary to teach back to student to be more respect the culture and local potentials in the region. There are many ways developing student character by exploring local wisdom and implementing them as a learning resources. This study aims at revealing the values of local wisdom Ngata Toro indigenous people of Central Sulawesi Province in managing forest as a source of learning biology. This research was conducted by in-depth interviews, participant non-observation, documentation studies, and field notes. The data were analyzed with triangulation techniques by using a qualitative interaction analysis that is data collection, data reduction, and data display. Ngata Toro local community manage forest by dividing the forest into several zones, those arewana ngkiki, wana, pangale, pahawa pongko, oma, and balingkea accompanied by rules in the management of result-based forest conservation and sustainable utilization. By identifying the purpose of zonation and regulation of the forest, such values as the value of environmental conservation, balance value, sustainable value, and the value of mutual cooperation. These values are implemented as a biological learning resource which derived from the competences standard of analyze the utilization and conservation of the environment.

Patterns of database citation in articles and patents indicate long-term scientific and industry value of biological data resources

Science.gov (United States)

Bousfield, David; McEntyre, Johanna; Velankar, Sameer; Papadatos, George; Bateman, Alex; Cochrane, Guy; Kim, Jee-Hyub; Graef, Florian; Vartak, Vid; Alako, Blaise; Blomberg, Niklas

2016-01-01

Data from open access biomolecular data resources, such as the European Nucleotide Archive and the Protein Data Bank are extensively reused within life science research for comparative studies, method development and to derive new scientific insights. Indicators that estimate the extent and utility of such secondary use of research data need to reflect this complex and highly variable data usage. By linking open access scientific literature, via Europe PubMedCentral, to the metadata in biological data resources we separate data citations associated with a deposition statement from citations that capture the subsequent, long-term, reuse of data in academia and industry.  We extend this analysis to begin to investigate citations of biomolecular resources in patent documents. We find citations in more than 8,000 patents from 2014, demonstrating substantial use and an important role for data resources in defining biological concepts in granted patents to both academic and industrial innovators. Combined together our results indicate that the citation patterns in biomedical literature and patents vary, not only due to citation practice but also according to the data resource cited. The results guard against the use of simple metrics such as citation counts and show that indicators of data use must not only take into account citations within the biomedical literature but also include reuse of data in industry and other parts of society by including patents and other scientific and technical documents such as guidelines, reports and grant applications. PMID:27092246

Patterns of database citation in articles and patents indicate long-term scientific and industry value of biological data resources.

Science.gov (United States)

Bousfield, David; McEntyre, Johanna; Velankar, Sameer; Papadatos, George; Bateman, Alex; Cochrane, Guy; Kim, Jee-Hyub; Graef, Florian; Vartak, Vid; Alako, Blaise; Blomberg, Niklas

2016-01-01

Data from open access biomolecular data resources, such as the European Nucleotide Archive and the Protein Data Bank are extensively reused within life science research for comparative studies, method development and to derive new scientific insights. Indicators that estimate the extent and utility of such secondary use of research data need to reflect this complex and highly variable data usage. By linking open access scientific literature, via Europe PubMedCentral, to the metadata in biological data resources we separate data citations associated with a deposition statement from citations that capture the subsequent, long-term, reuse of data in academia and industry.  We extend this analysis to begin to investigate citations of biomolecular resources in patent documents. We find citations in more than 8,000 patents from 2014, demonstrating substantial use and an important role for data resources in defining biological concepts in granted patents to both academic and industrial innovators. Combined together our results indicate that the citation patterns in biomedical literature and patents vary, not only due to citation practice but also according to the data resource cited. The results guard against the use of simple metrics such as citation counts and show that indicators of data use must not only take into account citations within the biomedical literature but also include reuse of data in industry and other parts of society by including patents and other scientific and technical documents such as guidelines, reports and grant applications.

Renewable Resources: a national catalog of model projects. Volume 3. Southern Solar Energy Center Region

Energy Technology Data Exchange (ETDEWEB)

None

1980-07-01

This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Southern Solar Energy Center Region. (WHK)

Renewable Resources: a national catalog of model projects. Volume 1. Northeast Solar Energy Center Region

Energy Technology Data Exchange (ETDEWEB)

None

1980-07-01

This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Northeast Solar Energy Center Region. (WHK).

Renewable Resources: a national catalog of model projects. Volume 4. Western Solar Utilization Network Region

Energy Technology Data Exchange (ETDEWEB)

None

1980-07-01

This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Western Solar Utilization Network Region. (WHK)

Simulation of biological flow and transport in complex geometries using embedded boundary/volume-of-fluid methods

International Nuclear Information System (INIS)

Trebotich, David

2007-01-01

We have developed a simulation capability to model multiscale flow and transport in complex biological systems based on algorithms and software infrastructure developed under the SciDAC APDEC CET. The foundation of this work is a new hybrid fluid-particle method for modeling polymer fluids in irregular microscale geometries that enables long-time simulation of validation experiments. Both continuum viscoelastic and discrete particle representations have been used to model the constitutive behavior of polymer fluids. Complex flow environment geometries are represented on Cartesian grids using an implicit function. Direct simulation of flow in the irregular geometry is then possible using embedded boundary/volume-of-fluid methods without loss of geometric detail. This capability has been used to simulate biological flows in a variety of application geometries including biomedical microdevices, anatomical structures and porous media

Temperature-dependent phase transitions in zeptoliter volumes of a complex biological membrane

International Nuclear Information System (INIS)

Nikiforov, Maxim P; Jesse, Stephen; Kalinin, Sergei V; Hohlbauch, Sophia; Proksch, Roger; King, William P; Voitchovsky, Kislon; Contera, Sonia Antoranz

2011-01-01

Phase transitions in purple membrane have been a topic of debate for the past two decades. In this work we present studies of a reversible transition of purple membrane in the 50-60 deg. C range in zeptoliter volumes under different heating regimes (global heating and local heating). The temperature of the reversible phase transition is 52 ± 5 deg. C for both local and global heating, supporting the hypothesis that this transition is mainly due to a structural rearrangement of bR molecules and trimers. To achieve high resolution measurements of temperature-dependent phase transitions, a new scanning probe microscopy-based method was developed. We believe that our new technique can be extended to other biological systems and can contribute to the understanding of inhomogeneous phase transitions in complex systems.

Modern water resources engineering

CERN Document Server

Yang, Chih

2014-01-01

The Handbook of Environmental Engineering series is an incredible collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. This exciting new addition to the series, Volume 15: Modern Water Resources Engineering , has been designed to serve as a water resources engineering reference book as well as a supplemental textbook. We hope and expect it will prove of equal high value to advanced undergraduate and graduate students, to designers of water resources systems, and to scientists and researchers. A critical volume in the Handbook of Environmental Engineering series, chapters employ methods of practical design and calculation illustrated by numerical examples, include pertinent cost data whenever possible, and explore in great detail the fundamental principles of the field. Volume 15: Modern Water Resources Engineering, provides information on some of the most innovative and ground-breaking advances in the field today from a panel of esteemed...

Wind energy resource atlas. Volume 9. The Southwest Region

Energy Technology Data Exchange (ETDEWEB)

Simon, R.L.; Norman, G.T.; Elliott, D.L.; Barchet, W.R.; George, R.L.

1980-11-01

This atlas of the wind energy resource is composed of introductory and background information, a regional summary of the wind resource, and assessments of the wind resource in Nevada and California. Background on how the wind resource is assessed and on how the results of the assessment should be interpreted is presented. A description of the wind resource on a regional scale is then given. The results of the wind energy assessments for each state are assembled into an overview and summary of the various features of the regional wind energy resource. An introduction and outline to the descriptions of the wind resource given for each state are given. Assessments for individual states are presented as separate chapters. The state wind energy resources are described in greater detail than is the regional wind energy resource, and features of selected stations are discussed.

Assessing impacts on biological resources from Site Characterization Activities of the Yucca Mountain Project

International Nuclear Information System (INIS)

Green, R.A.; Cox, M.K.; Doerr, T.B.; O'Farrell, T.P.; Ostler, W.K.; Rautenstrauch, K.R.; Wills, C.A.

1991-01-01

An integrated impact assessment program was developed to monitor the possible effects of Site Characterization Activities (SCA) on the biological resources of the Yucca Mountain area. The program uses control and treatment sites incorporating both spatial and temporal controls. The selection of biotic variables for monitoring was based on their relative importance in the ecosystem and their ability to provide information on potential impacts. All measures of biotic and abiotic variables will be made on the same sample plots to permit linking changes in variables to each other

Biologic lung volume reduction in advanced upper lobe emphysema: phase 2 results.

Science.gov (United States)

Criner, Gerard J; Pinto-Plata, Victor; Strange, Charlie; Dransfield, Mark; Gotfried, Mark; Leeds, William; McLennan, Geoffrey; Refaely, Yael; Tewari, Sanjiv; Krasna, Mark; Celli, Bartolome

2009-05-01

Biologic lung volume reduction (BioLVR) is a new endobronchial treatment for advanced emphysema that reduces lung volume through tissue remodeling. Assess the safety and therapeutic dose of BioLVR hydrogel in upper lobe predominant emphysema. Open-labeled, multicenter phase 2 dose-ranging studies were performed with BioLVR hydrogel administered to eight subsegmental sites (four in each upper lobe) involving: (1) low-dose treatment (n = 28) with 10 ml per site (LD); and (2) high-dose treatment (n = 22) with 20 ml per site (HD). Safety was assessed by the incidence of serious medical complications. Efficacy was assessed by change from baseline in pulmonary function tests, dyspnea score, 6-minute walk distance, and health-related quality of life. After treatment there were no deaths and four serious treatment-related complications. A reduction in residual volume to TLC ratio at 12 weeks (primary efficacy outcome) was achieved with both LD (-6.4 +/- 9.3%; P = 0.002) and HD (-5.5 +/- 9.4%; P = 0.028) treatments. Improvements in pulmonary function in HD (6 mo: DeltaFEV(1) = +15.6%; P = 0.002; DeltaFVC = +9.1%; P = 0.034) were greater than in LD patients (6 mo: DeltaFEV(1) = +6.7%; P = 0.021; DeltaFVC = +5.1%; P = 0.139). LD- and HD-treated groups both demonstrated improved symptom scores and health-related quality of life. BioLVR improves physiology and functional outcomes up to 6 months with an acceptable safety profile in upper lobe predominant emphysema. Overall improvement was greater and responses more durable with 20 ml per site than 10 ml per site dosing. Clinical trial registered with www.clinicaltrials.gov (NCT 00435253 and NCT 00515164).

A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research

Directory of Open Access Journals (Sweden)

Lutz Kockel

2016-10-01

Full Text Available Novel binary gene expression tools like the LexA-LexAop system could powerfully enhance studies of metabolism, development, and neurobiology in Drosophila. However, specific LexA drivers for neuroendocrine cells and many other developmentally relevant systems remain limited. In a unique high school biology course, we generated a LexA-based enhancer trap collection by transposon mobilization. The initial collection provides a source of novel LexA-based elements that permit targeted gene expression in the corpora cardiaca, cells central for metabolic homeostasis, and other neuroendocrine cell types. The collection further contains specific LexA drivers for stem cells and other enteric cells in the gut, and other developmentally relevant tissue types. We provide detailed analysis of nearly 100 new LexA lines, including molecular mapping of insertions, description of enhancer-driven reporter expression in larval tissues, and adult neuroendocrine cells, comparison with established enhancer trap collections and tissue specific RNAseq. Generation of this open-resource LexA collection facilitates neuroendocrine and developmental biology investigations, and shows how empowering secondary school science can achieve research and educational goals.

Equitably sharing benefits from the utilization of natural genetic resources: the Brazilian interpretation of the Convention of Biological Diversity

NARCIS (Netherlands)

Pena-Neira, S.; Dieperink, C.; Addink, G.H.

2002-01-01

The utilization of natural genetic resources could yield great benefits. The Convention on Biological Diversity introduced a number of rules concerning the sharing of these benefits. However, the interpretation and application (legal implementation) of these rules is a matter of discussion among

Space Biology and Medicine. Volume 4; Health, Performance, and Safety of Space Crews

Science.gov (United States)

Dietlein, Lawrence F. (Editor); Pestov, Igor D. (Editor)

2004-01-01

Volume IV is devoted to examining the medical and associated organizational measures used to maintain the health of space crews and to support their performance before, during, and after space flight. These measures, collectively known as the medical flight support system, are important contributors to the safety and success of space flight. The contributions of space hardware and the spacecraft environment to flight safety and mission success are covered in previous volumes of the Space Biology and Medicine series. In Volume IV, we address means of improving the reliability of people who are required to function in the unfamiliar environment of space flight as well as the importance of those who support the crew. Please note that the extensive collaboration between Russian and American teams for this volume of work resulted in a timeframe of publication longer than originally anticipated. Therefore, new research or insights may have emerged since the authors composed their chapters and references. This volume includes a list of authors' names and addresses should readers seek specifics on new information. At least three groups of factors act to perturb human physiological homeostasis during space flight. All have significant influence on health, psychological, and emotional status, tolerance, and work capacity. The first and most important of these factors is weightlessness, the most specific and radical change in the ambient environment; it causes a variety of functional and structural changes in human physiology. The second group of factors precludes the constraints associated with living in the sealed, confined environment of spacecraft. Although these factors are not unique to space flight, the limitations they entail in terms of an uncomfortable environment can diminish the well-being and performance of crewmembers in space. The third group of factors includes the occupational and social factors associated with the difficult, critical nature of the

Geospatial characteristics of Florida's coastal and offshore environments: Distribution of important habitats for coastal and offshore biological resources and offshore sand resources

Science.gov (United States)

Demopoulos, Amanda W.J.; Foster, Ann M.; Jones, Michal L.; Gualtieri, Daniel J.

2011-01-01

The Geospatial Characteristics GeoPDF of Florida's Coastal and Offshore Environments is a comprehensive collection of geospatial data describing the political boundaries and natural resources of Florida. This interactive map provides spatial information on bathymetry, sand resources, and locations of important habitats (for example, Essential Fish Habitats (EFH), nesting areas, strandings) for marine invertebrates, fish, reptiles, birds, and marine mammals. The map should be useful to coastal resource managers and others interested in marine habitats and submerged obstructions of Florida's coastal region. In particular, as oil and gas explorations continue to expand, the map can be used to explore information regarding sensitive areas and resources in the State of Florida. Users of this geospatial database will have access to synthesized information in a variety of scientific disciplines concerning Florida's coastal zone. This powerful tool provides a one-stop assembly of data that can be tailored to fit the needs of many natural resource managers. The map was originally developed to assist the Bureau of Ocean Energy Management, Regulation, and Enforcement (BOEMRE) and coastal resources managers with planning beach restoration projects. The BOEMRE uses a systematic approach in planning the development of submerged lands of the Continental Shelf seaward of Florida's territorial waters. Such development could affect the environment. BOEMRE is required to ascertain the existing physical, biological, and socioeconomic conditions of the submerged lands and estimate the impact of developing these lands. Data sources included the National Oceanic and Atmospheric Administration, BOEMRE, Florida Department of Environmental Protection, Florida Geographic Data Library, Florida Fish and Wildlife Conservation Commission, Florida Natural Areas Inventory, and the State of Florida, Bureau of Archeological Research. Federal Geographic Data Committee (FGDC) compliant metadata are

Planning manual for energy resource development on Indian lands. Volume III. Manpower and training

Energy Technology Data Exchange (ETDEWEB)

1978-03-01

This volume addresses ways to bridge the gap between existing tribal skill levels and the skill levels required for higher-paying jobs in energy resource development projects. It addresses opportunities for technical, skilled, and semiskilled employment as well as professional positions, because it is important to have tribal participation at all levels of an operation. Section II, ''Energy-Related Employment Opportunities,'' covers three areas: (1) identification of energy-resource occupations; (2) description of these occupations; and (3) identification of skill requirements by type of occupation. Section III, ''Description of Training Programs,'' also covers three areas: (a) concept of a training-program model; (b) description of various training methods; and (c) an assessment of the cost of training, utilizing different programs. Section IV concentrates on development of a training program for target occupations, skills, and populations. Again this section covers three areas: (i) overview of the development of a skills training program; (ii) identification of target occupations, skills, and populations; and (iii) energy careers for younger tribal members.

Investment into the future of microbial resources: culture collection funding models and BRC business plans for biological resource centres.

Science.gov (United States)

Smith, David; McCluskey, Kevin; Stackebrandt, Erko

2014-01-01

Through their long history of public service, diverse microbial Biological Resource Centres (mBRCs) have made myriad contributions to society and science. They have enabled the maintenance of specimens isolated before antibiotics, made available strains showing the development and change of pathogenicity toward animals, humans and plants, and have maintained and provided reference strains to ensure quality and reproducibility of science. However, this has not been achieved without considerable financial commitment. Different collections have unique histories and their support is often tied to their origins. However many collections have grown to serve large constituencies and need to develop novel funding mechanisms. Moreover, several international initiatives have described mBRCs as a factor in economic development and have led to the increased professionalism among mBRCs.

Biology as an Integrating Natural Science Domain

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 3. Biology as an Integrating Natural Science Domain: A Proposal for BSc (Hons) in Integrated Biology. Kambadur Muralidhar. Classroom Volume 13 Issue 3 March 2008 pp 272-276 ...

The Colorado Plateau III: integrating research and resources management for effective conservation

Science.gov (United States)

Sogge, Mark K.; van Riper, Charles

2008-01-01

Roughly centered on the Four Corners region of the southwestern United States, the Colorado Plateau covers an area of 130,000 square miles. The relatively high semi-arid province boasts nine national parks, sixteen national monuments, many state parks, and dozens of wilderness areas. With the highest concentration of parklands in North America and unique geological and ecological features, the area is of particular interest to researchers. Derived from the Eighth Biennial Conference of Research on the Colorado Plateau, this third volume in a series of research on the Colorado Plateau expands upon the previous two books. This volume focuses on the integration of science into resource management issues, summarizes what criteria make a successful collaborative effort, outlines land management concerns about drought, provides summaries of current biological, sociological, and archaeological research, and highlights current environmental issues in the Four Corner States of Arizona, New Mexico, Colorado, and Utah. With broad coverage that touches on topics as diverse as historical aspects of pronghorn antelope movement patterns through calculating watershed prescriptions to the role of wind-blown sand in preserving archaeological sites on the Colorado River, this volume stands as a compendium of cuttingedge management-oriented research on the Colorado Plateau. The book also introduces, for the first time, tools that can be used to assist with collaboration efforts among landowners and managers who wish to work together toward preserving resources on the Colorado Plateau and offers a wealth of insights into land management questions for many readers, especially people interested in the natural history, biology, anthropology, wildlife, and cultural management issues of the region.

Biological basis of detoxication

National Research Council Canada - National Science Library

Caldwell, John; Jakoby, William B

1983-01-01

This volume considers that premise that most of the major patterns of biological conversion of foreign compounds are known and may have predictive value in assessing the biological course for novel compounds...

Renewable Resources: a national catalog of model projects. Volume 2. Mid-American Solar Energy Complex Region

Energy Technology Data Exchange (ETDEWEB)

None

1980-07-01

This compilation of diverse conservation and renewable energy projects across the United States was prepared through the enthusiastic participation of solar and alternate energy groups from every state and region. Compiled and edited by the Center for Renewable Resources, these projects reflect many levels of innovation and technical expertise. In many cases, a critique analysis is presented of how projects performed and of the institutional conditions associated with their success or failure. Some 2000 projects are included in this compilation; most have worked, some have not. Information about all is presented to aid learning from these experiences. The four volumes in this set are arranged in state sections by geographic region, coinciding with the four Regional Solar Energy Centers. The table of contents is organized by project category so that maximum cross-referencing may be obtained. This volume includes information on the Mid-American Solar Energy Complex Region. (WHK)

Investigating the Marine Environment and Its Resources, Part II.

Science.gov (United States)

Lien, Violetta F.

This is the second of two volumes comprising a resource unit designed to help students become more knowledgeable about the marine environment and its resources. Included in this volume are discussions of changes in the human and marine environment, human needs, marine resources, living marine resources, marine transportation, marine energy…

Potential of chicken by-products as sources of useful biological resources

International Nuclear Information System (INIS)

Lasekan, Adeseye; Abu Bakar, Fatimah; Hashim, Dzulkifly

2013-01-01

By-products from different animal sources are currently being utilised for beneficial purposes. Chicken processing plants all over the world generate large amount of solid by-products in form of heads, legs, bones, viscera and feather. These wastes are often processed into livestock feed, fertilizers and pet foods or totally discarded. Inappropriate disposal of these wastes causes environmental pollution, diseases and loss of useful biological resources like protein, enzymes and lipids. Utilisation methods that make use of these biological components for producing value added products rather than the direct use of the actual waste material might be another viable option for dealing with these wastes. This line of thought has consequently led to researches on these wastes as sources of protein hydrolysates, enzymes and polyunsaturated fatty acids. Due to the multi-applications of protein hydrolysates in various branches of science and industry, and the large body of literature reporting the conversion of animal wastes to hydrolysates, a large section of this review was devoted to this subject. Thus, this review reports the known functional and bioactive properties of hydrolysates derived from chicken by-products as well their utilisation as source of peptone in microbiological media. Methods of producing these hydrolysates including their microbiological safety are discussed. Based on the few references available in the literature, the potential of some chicken by-product as sources of proteases and polyunsaturated fatty acids are pointed out along with some other future applications

Potential of chicken by-products as sources of useful biological resources

Energy Technology Data Exchange (ETDEWEB)

Lasekan, Adeseye [Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Abu Bakar, Fatimah, E-mail: fatim@putra.upm.edu.my [Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Halal Products Research Institute, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Hashim, Dzulkifly [Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Halal Products Research Institute, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia)

2013-03-15

By-products from different animal sources are currently being utilised for beneficial purposes. Chicken processing plants all over the world generate large amount of solid by-products in form of heads, legs, bones, viscera and feather. These wastes are often processed into livestock feed, fertilizers and pet foods or totally discarded. Inappropriate disposal of these wastes causes environmental pollution, diseases and loss of useful biological resources like protein, enzymes and lipids. Utilisation methods that make use of these biological components for producing value added products rather than the direct use of the actual waste material might be another viable option for dealing with these wastes. This line of thought has consequently led to researches on these wastes as sources of protein hydrolysates, enzymes and polyunsaturated fatty acids. Due to the multi-applications of protein hydrolysates in various branches of science and industry, and the large body of literature reporting the conversion of animal wastes to hydrolysates, a large section of this review was devoted to this subject. Thus, this review reports the known functional and bioactive properties of hydrolysates derived from chicken by-products as well their utilisation as source of peptone in microbiological media. Methods of producing these hydrolysates including their microbiological safety are discussed. Based on the few references available in the literature, the potential of some chicken by-product as sources of proteases and polyunsaturated fatty acids are pointed out along with some other future applications.

Resource Programs : Draft Environmental Impact Statement, Volume 2, Appendices.

Energy Technology Data Exchange (ETDEWEB)

United States. Bonneville Power Administration.

1992-03-01

Every two years, Bonneville Power Administration (BPA) prepares a Resource Program which identifies the resource actions BPA will take to meet its obligation to serve the forecasted power requirements of its customers. The Resource Program`s Environmental Impact Statement (RPEIS) is a programmatic environmental document which will support decisions made in several future Resource Programs. Environmental documents tiered to the EIS may be prepared on a site-specific basis. The RPEIS includes a description of the environmental effects and mitigation for the various resource types available in order to evaluate the trade-offs among them. It also assesses the environmental impacts of adding thirteen alternative combinations of resources to the existing power system. This report contains the appendices to the RPEIS.

University of all knowledge. Nature and risks. Volume 6; Universite de tous les savoirs. La nature et les risques. Volume 6

Energy Technology Data Exchange (ETDEWEB)

Michaud, Y.

2002-02-01

This small book belongs to a collection of six volumes which synthesizes the content of a cycle of 366 conferences about sciences, techniques, intellectual productions, cultures etc, given each day of the year 2000 by specialists of the relevant domains. This 6. volume is devoted to todays and tomorrows stakes of nature: bio-diversity; co-evolution; molecular dialogue of symbioses; the vegetal chemical factory; the appropriation of the living matter: from biology to the social debate; the ethical stakes of genetics; todays feeding and risk perception; tomorrows feeding; safety of food products: prevention - surveillance - crisis; nature and agriculture; function and response of plant leaves to aggressions and herbicides; fishes and men (resources management); plants, molecules and drugs; the future of fossil fuels; the future of the environment; water pollution and cleansing; wastes: how the eliminate, re-valorize or avoid them; soils pollution; the ambiguousness of sustainable development policies; liability, risk and precaution. (J.S.)

Biology of Blood

Science.gov (United States)

... switch to the Professional version Home Blood Disorders Biology of Blood Overview of Blood Resources In This ... Version. DOCTORS: Click here for the Professional Version Biology of Blood Overview of Blood Components of Blood ...

The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology.

Science.gov (United States)

Huang, Jingshan; Eilbeck, Karen; Smith, Barry; Blake, Judith A; Dou, Dejing; Huang, Weili; Natale, Darren A; Ruttenberg, Alan; Huan, Jun; Zimmermann, Michael T; Jiang, Guoqian; Lin, Yu; Wu, Bin; Strachan, Harrison J; He, Yongqun; Zhang, Shaojie; Wang, Xiaowei; Liu, Zixing; Borchert, Glen M; Tan, Ming

2016-01-01

In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of information being obtained in this area, there emerges an urgent need to integrate what is being discovered by a broad range of relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a systematically structured and precisely defined controlled vocabulary for the domain of ncRNAs, thereby facilitating the discovery, curation, analysis, exchange, and reasoning of data about structures of ncRNAs, their molecular and cellular functions, and their impacts upon phenotypes. The goal of NCRO is to serve as a common resource for annotations of diverse research in a way that will significantly enhance integrative and comparative analysis of the myriad resources currently housed in disparate sources. It is our belief that the NCRO ontology can perform an important role in the comprehensive unification of ncRNA biology and, indeed, fill a critical gap in both the Open Biological and Biomedical Ontologies (OBO) Library and the National Center for Biomedical Ontology (NCBO) BioPortal. Our initial focus is on the ontological representation of small regulatory ncRNAs, which we see as the first step in providing a resource for the annotation of data about all forms of ncRNAs. The NCRO ontology is free and open to all users, accessible at: http://purl.obolibrary.org/obo/ncro.owl.

A note on stereological estimation of the volume-weighted second moment of particle volume

DEFF Research Database (Denmark)

Jensen, E B; Sørensen, Flemming Brandt

1991-01-01

It is shown that for a variety of biological particle shapes, the volume-weighted second moment of particle volume can be estimated stereologically using only the areas of particle transects, which can be estimated manually by point-counting....

Environmental-Economic Accounts and Financial Resource Mobilisation for Implementation the Convention on Biological Diversity

Directory of Open Access Journals (Sweden)

Cesare Costantino

2015-12-01

Full Text Available At the Rio “Earth Summit” the Convention on Biological Diversity introduced a global commitment to conservation of biological diversity and sustainable use of its components. An implementation process is going on, based on a strategic plan, biodiversity targets and a strategy for mobilizing financial resources. According to target “2”, by 2020 national accounts should include monetary aggregates related to biodiversity. Environmental accounts can play an important role – together with other information – in monitoring processes connected with target “20”: contribute to identifying activities needed to preserve biodiversity, calculating the associated costs and eventually assessing funding needs. In particular, EPEA and ReMEA are valuable accounting tools for providing data on biodiversity expenditure. The high quality of the information provided by these accounts makes them good candidates for being adopted world-wide within the Convention’s monitoring processes. Enhanced interaction between statisticians and officials from ministries of environment would be crucial to reach significant advancement towards standardization of the information used in support of the Convention.

Human Resource Management in Virtual Organizations. Research in Human Resource Management Series.

Science.gov (United States)

Heneman, Robert L., Ed.; Greenberger, David B., Ed.

This document contains 14 papers on human resources (HR) and human resource management (HRM) in virtual organizations. The following papers are included: "Series Preface" (Rodger Griffeth); "Volume Preface" (Robert L. Heneman, David B. Greenberger); "The Virtual Organization: Definition, Description, and…

Identifying ELIXIR Core Data Resources.

Science.gov (United States)

Durinx, Christine; McEntyre, Jo; Appel, Ron; Apweiler, Rolf; Barlow, Mary; Blomberg, Niklas; Cook, Chuck; Gasteiger, Elisabeth; Kim, Jee-Hyub; Lopez, Rodrigo; Redaschi, Nicole; Stockinger, Heinz; Teixeira, Daniel; Valencia, Alfonso

2016-01-01

The core mission of ELIXIR is to build a stable and sustainable infrastructure for biological information across Europe. At the heart of this are the data resources, tools and services that ELIXIR offers to the life-sciences community, providing stable and sustainable access to biological data. ELIXIR aims to ensure that these resources are available long-term and that the life-cycles of these resources are managed such that they support the scientific needs of the life-sciences, including biological research. ELIXIR Core Data Resources are defined as a set of European data resources that are of fundamental importance to the wider life-science community and the long-term preservation of biological data. They are complete collections of generic value to life-science, are considered an authority in their field with respect to one or more characteristics, and show high levels of scientific quality and service. Thus, ELIXIR Core Data Resources are of wide applicability and usage. This paper describes the structures, governance and processes that support the identification and evaluation of ELIXIR Core Data Resources. It identifies key indicators which reflect the essence of the definition of an ELIXIR Core Data Resource and support the promotion of excellence in resource development and operation. It describes the specific indicators in more detail and explains their application within ELIXIR's sustainability strategy and science policy actions, and in capacity building, life-cycle management and technical actions. The identification process is currently being implemented and tested for the first time. The findings and outcome will be evaluated by the ELIXIR Scientific Advisory Board in March 2017. Establishing the portfolio of ELIXIR Core Data Resources and ELIXIR Services is a key priority for ELIXIR and publicly marks the transition towards a cohesive infrastructure.

Tested Studies for Laboratory Teaching. Proceedings of the Workshop/Conference of the Association for Biology Laboratory Education (ABLE) (13th, Laramie, Wyoming, June 11-15, 1991). Volume 13.

Science.gov (United States)

Goldman, Corey A., Ed.

The focus of the Association for Biology Laboratory Education (ABLE) is to improve the undergraduate biology laboratory experience by promoting the development and dissemination of interesting, innovative, and reliable laboratory exercises. This proceedings volume contains 10 papers: "Testing Issues of Foraging and Flocking Behavior" (C. C.…

Human Ageing Genomic Resources: Integrated databases and tools for the biology and genetics of ageing

Science.gov (United States)

Tacutu, Robi; Craig, Thomas; Budovsky, Arie; Wuttke, Daniel; Lehmann, Gilad; Taranukha, Dmitri; Costa, Joana; Fraifeld, Vadim E.; de Magalhães, João Pedro

2013-01-01

The Human Ageing Genomic Resources (HAGR, http://genomics.senescence.info) is a freely available online collection of research databases and tools for the biology and genetics of ageing. HAGR features now several databases with high-quality manually curated data: (i) GenAge, a database of genes associated with ageing in humans and model organisms; (ii) AnAge, an extensive collection of longevity records and complementary traits for >4000 vertebrate species; and (iii) GenDR, a newly incorporated database, containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction. Since its creation about 10 years ago, major efforts have been undertaken to maintain the quality of data in HAGR, while further continuing to develop, improve and extend it. This article briefly describes the content of HAGR and details the major updates since its previous publications, in terms of both structure and content. The completely redesigned interface, more intuitive and more integrative of HAGR resources, is also presented. Altogether, we hope that through its improvements, the current version of HAGR will continue to provide users with the most comprehensive and accessible resources available today in the field of biogerontology. PMID:23193293

Resources in Technology 7.

Science.gov (United States)

International Technology Education Association, Reston, VA.

This volume of Resources in Technology contains the following eight instructional modules: (1) "Processing Technology"; (2) "Water--A Magic Resource"; (3) "Hazardous Waste Disposal--The NIMBY (Not in My Backyard) Syndrome"; (4) "Processing Fibers and Fabrics"; (5) "Robotics--An Emerging…

Research Collaboration Workshop for Women in Mathematical Biology

CERN Document Server

Miller, Laura

2017-01-01

Inspired by the Research Collaboration Workshop for Women in Mathematical Biology, this volume contains research and review articles that cover topics ranging from models of animal movement to the flow of blood cells in the embryonic heart. Hosted by the National Institute for Mathematics and Biological Synthesis (NIMBioS), the workshop brought together women working in biology and mathematics to form four research groups that encouraged multidisciplinary collaboration and lifetime connections in the STEM field. This volume introduces many of the topics from the workshop, including the aerodynamics of spider ballooning; sleep, circadian rhythms, and pain; blood flow regulation in the kidney; and the effects of antimicrobial therapy on gut microbiota and microbiota and Clostridium difficile. Perfect for students and researchers in mathematics and biology, the papers included in this volume offer an introductory glimpse at recent research in mathematical biology. .

Neutron Scattering in Biology Techniques and Applications

CERN Document Server

Fitter, Jörg; Katsaras, John

2006-01-01

The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.

Genome Scale Modeling in Systems Biology: Algorithms and Resources

Science.gov (United States)

Najafi, Ali; Bidkhori, Gholamreza; Bozorgmehr, Joseph H.; Koch, Ina; Masoudi-Nejad, Ali

2014-01-01

In recent years, in silico studies and trial simulations have complemented experimental procedures. A model is a description of a system, and a system is any collection of interrelated objects; an object, moreover, is some elemental unit upon which observations can be made but whose internal structure either does not exist or is ignored. Therefore, any network analysis approach is critical for successful quantitative modeling of biological systems. This review highlights some of most popular and important modeling algorithms, tools, and emerging standards for representing, simulating and analyzing cellular networks in five sections. Also, we try to show these concepts by means of simple example and proper images and graphs. Overall, systems biology aims for a holistic description and understanding of biological processes by an integration of analytical experimental approaches along with synthetic computational models. In fact, biological networks have been developed as a platform for integrating information from high to low-throughput experiments for the analysis of biological systems. We provide an overview of all processes used in modeling and simulating biological networks in such a way that they can become easily understandable for researchers with both biological and mathematical backgrounds. Consequently, given the complexity of generated experimental data and cellular networks, it is no surprise that researchers have turned to computer simulation and the development of more theory-based approaches to augment and assist in the development of a fully quantitative understanding of cellular dynamics. PMID:24822031

The Importance of Biological Databases in Biological Discovery.

Science.gov (United States)

Baxevanis, Andreas D; Bateman, Alex

2015-06-19

Biological databases play a central role in bioinformatics. They offer scientists the opportunity to access a wide variety of biologically relevant data, including the genomic sequences of an increasingly broad range of organisms. This unit provides a brief overview of major sequence databases and portals, such as GenBank, the UCSC Genome Browser, and Ensembl. Model organism databases, including WormBase, The Arabidopsis Information Resource (TAIR), and those made available through the Mouse Genome Informatics (MGI) resource, are also covered. Non-sequence-centric databases, such as Online Mendelian Inheritance in Man (OMIM), the Protein Data Bank (PDB), MetaCyc, and the Kyoto Encyclopedia of Genes and Genomes (KEGG), are also discussed. Copyright © 2015 John Wiley & Sons, Inc.

Technical procedures for water resources, Deaf Smith County site, Texas: Volume 2: Environmental Field Program: Final draft

International Nuclear Information System (INIS)

1987-08-01

This volume contains the following Technical Procedures pursuant to the Water Resources Site Study Plan operation of a Playa Lake conductivity monitoring station and processing of data from a Playa Lake conductivity monitoring station. This procedure defines steps and methods for the installation, operation, and maintenance of the Playa Lake conductivity monitoring stations. Conductivity measurements will be taken at six playa lakes in the site study area to record changes in total dissolved solids as a function of stage. Playa lake conductivity and stage (volume) measurements will be used, in conjunction with other water quality data collected at the Playa Lake and precipitation stations, to determine the mass of dissolved solids entering and leaving the playas. This baseline information on the pollutant mass balance of the playas will be used to assess potential changes in playa lake water quality and the magnitude of those changes due to site development. The pollutant mass balances will also be used on determining the source of pollutants. 2 refs., 5 figs

Tested Studies for Laboratory Teaching. Proceedings of the Workshop/Conference of the Association for Biology Laboratory Education (ABLE) (15th, Toronto, Ontario, Canada, June 8-12, 1993). Volume 15.

Science.gov (United States)

Goldman, Corey A., Ed.

The focus of the Association for Biology Laboratory Education (ABLE) is to improve the undergraduate biology laboratory experience by promoting the development and dissemination of interesting, innovative, and reliable laboratory exercises. This proceedings volume contains 18 papers: "Human DNA Fingerprinting by Polymerase Chain Reaction" (M. V.…

Advances in water resources engineering

CERN Document Server

Wang, Lawrence

2015-01-01

The Handbook of Environmental Engineering is a collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. A sister volume to Volume 15: Modern Water Resources Engineering, this volume focuses on the theory and analysis of various water resources systems including watershed sediment dynamics and modeling, integrated simulation of interactive surface water and groundwater systems, river channel stabilization with submerged vanes, non-equilibrium sediment transport, reservoir sedimentation, and fluvial processes, minimum energy dissipation rate theory and applications, hydraulic modeling development and application, geophysical methods for assessment of earthen dams, soil erosion on upland areas by rainfall and overland flow, geofluvial modeling methodologies and applications, and an environmental water engineering glossary. This critical volume will serve as a valuable reference work for advanced undergraduate and graduate students, designers of...

Biological condition gradient: Applying a framework for determining the biological integrity of coral reefs

Science.gov (United States)

The goals of the U.S. Clean Water Act (CWA) are to restore and maintain the chemical, physical and biological integrity of water resources. Although clean water is a goal, another is to safeguard biological communities by defining levels of biological integrity to protect aquatic...

Biological interactions and cooperative management of multiple species.

Science.gov (United States)

Jiang, Jinwei; Min, Yong; Chang, Jie; Ge, Ying

2017-01-01

Coordinated decision making and actions have become the primary solution for the overexploitation of interacting resources within ecosystems. However, the success of coordinated management is highly sensitive to biological, economic, and social conditions. Here, using a game theoretic framework and a 2-species model that considers various biological relationships (competition, predation, and mutualism), we compute cooperative (or joint) and non-cooperative (or separate) management equilibrium outcomes of the model and investigate the effects of the type and strength of the relationships. We find that cooperation does not always show superiority to non-cooperation in all biological interactions: (1) if and only if resources are involved in high-intensity predation relationships, cooperation can achieve a win-win scenario for ecosystem services and resource diversity; (2) for competitive resources, cooperation realizes higher ecosystem services by sacrificing resource diversity; and (3) for mutual resources, cooperation has no obvious advantage for either ecosystem services or resource evenness but can slightly improve resource abundance. Furthermore, by using a fishery model of the North California Current Marine Ecosystem with 63 species and seven fleets, we demonstrate that the theoretical results can be reproduced in real ecosystems. Therefore, effective ecosystem management should consider the interconnection between stakeholders' social relationship and resources' biological relationships.

Method and Mchievement of Survey and Evaluation of Groundwater Resources of Guangzhou City

Science.gov (United States)

Lin, J.

2017-12-01

Based on the documents and achievements relevant to hydrogeological surveying and mapping of 1:100000, hydrogeological drilling, pumping test and dynamic monitoring of groundwater level in Guangzhou, considering the hydrogeological conditions of Guangzhou and combining the advanced technologies such as remote sensing, the survey and evaluation of the volume of the groundwater resources of Guangzhou was carried out in plain and mountain areas separately. The recharge method was used to evaluate the volume of groundwater resources in plain areas, meanwhile, the output volume and the storage change volume of groundwater were calculated and the volume of groundwater resources was corrected by water balance analysis; while the discharge method was used to evaluated the volume of groundwater resources in mountain areas. The result of survey and evaluation indicates that: the volume of the natural groundwater resources in Guangzhou City is 1.83 billion m3 of which the groundwater replenishment quantity in plain areas is 510,045,000 m3, with a total output of 509,729,000 m3, an absolute balance difference of 316,000 m3 and a relative balance difference of 0.062%; the volume of groundwater resources in mountain areas is 1,358,208,000 m3 including the river basic flow is 965,054,000 m3; the repetitive counted volume of groundwater resources in both plain areas and mountain areas is 38,839,000 m3. This work was realized by refined means for the first time to entirely find out the volume of groundwater resources of Guangzhou City and the law of their distribution so as to lay an important foundation for the protection and reasonable development and exploration of the groundwater resources of Guangzhou City.

Ernst Mayr and Evolutionary Biology

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 10; Issue 7. Polemics and Synthesis: Ernst Mayr and Evolutionary Biology. Renee M Borges. General Article Volume 10 Issue 7 July 2005 pp 21-33. Fulltext. Click here to view fulltext PDF. Permanent link:

Structural Molecular Biology 2017 | SSRL

Science.gov (United States)

Highlights Training Workshops & Summer Schools Summer Students Structural Molecular Biology Illuminating experimental driver for structural biology research, serving the needs of a large number of academic and — Our Mission The SSRL Structural Molecular Biology program operates as an integrated resource and has

Structural Biology: Practical NMR Applications

CERN Document Server

Teng, Quincy

2005-01-01

This textbook begins with an overview of NMR development and applications in biological systems. It describes recent developments in instrument hardware and methodology. Chapters highlight the scope and limitation of NMR methods. While detailed math and quantum mechanics dealing with NMR theory have been addressed in several well-known NMR volumes, chapter two of this volume illustrates the fundamental principles and concepts of NMR spectroscopy in a more descriptive manner. Topics such as instrument setup, data acquisition, and data processing using a variety of offline software are discussed. Chapters further discuss several routine stategies for preparing samples, especially for macromolecules and complexes. The target market for such a volume includes researchers in the field of biochemistry, chemistry, structural biology and biophysics.

Water resources data, Ohio: Water year 1991. Volume 1, Ohio River Basin excluding project data

Energy Technology Data Exchange (ETDEWEB)

Shindel, H.L.; Klingler, J.H.; Mangus, J.P.; Trimble, L.E.

1992-03-01

Water-resources data for the 1991 water year for Ohio consist of records of stage, discharge, and water quality of streams; stage and contents of lakes and reservoirs; and water levels and water quality of ground-water wells. This report, in two volumes, contains records for water discharge at 131 gaging stations, 378 wells, and 74 partial-record sites; and water levels at 431 observation wells. Also included are data from miscellaneous sites. Additional water data were collected at various sites not involved in the systematic data-collection program and are published as miscellaneous measurements and analyses. These data represent that part of the National Water Data System collected by the US Geological Survey and cooperating State and Federal agencies in Ohio.

Michael Levitt and Computational Biology

Science.gov (United States)

dropdown arrow Site Map A-Z Index Menu Synopsis Michael Levitt and Computational Biology Resources with Michael Levitt, PhD, professor of structural biology at the Stanford University School of Medicine, has function. ... Levitt's early work pioneered computational structural biology, which helped to predict

DEVELOPMENT OFINDICATORSFOR EFFECTIVE USE OF INTERIMMATERIAL RESOURCES

Directory of Open Access Journals (Sweden)

Klimuk V. V.

2014-03-01

Full Text Available The article provides the developed methodology of the midterm evaluation of the efficiency of use of material resources. Proposed system of indicators for tracking and monitoring of the efficiency of the production process. The author analyzes literary sources on the problem of the estimation of efficiency of use of material resources, we study the opinions of economists. The author summarizes the observational information and provides conclusions expressed in the reflection of the urgency of forming the system of the midterm evaluation of the efficiency of use of material resources. the traditional system assessment, the method of using of which is presented in the works of scientists, does not contain indicators reflecting the interim targets with the aim of forming a preliminary picture of the future condition of efficiency of use of material resources, on the basis of the quarterly rate of change of the level of material consumption, comparing them to the beginning and end of the time period, the balance of the stock of material resources, mapping the rate of change of the volume of production and the rate of change of material costs, matching the pace of change of volume of purchases of material resources and the pace of changes in the value of material resources, the Author proposes indicators: the rate of change of material capacity for 4 quarter, comparison of the rates of change in material consumption in the 1st and 4th quarters, the balance of the stock of material resources, the rate of change of the volume of production and material costs by quarter, the comparison of the rate of change of volume of purchases of material resources with the pace of changes in the value of material resources by quarter. The theoretical significance of the test is to use the author of the material as an additional reading course of lectures on economic subjects, practical significance - the inclusion of a set of indicators developed as a tool

How Computers are Arming biology!

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 23; Issue 1. In-vitro to In-silico - How Computers are Arming biology! Geetha Sugumaran Sushila Rajagopal. Face to Face Volume 23 Issue 1 January 2018 pp 83-102. Fulltext. Click here to view fulltext PDF. Permanent link:

Timber resources of southwest Oregon.

Science.gov (United States)

Patricia M. Bassett

1979-01-01

This report presents statistics from a 1973 inventory of timber resources of Douglas County and from a 1974 inventory of timber resources of Coos, Curry, Jackson, and Josephine Counties, Oregon. Tables presented are of forest area and of timber volume, growth, and mortality.

VISUALIZATION OF BIOLOGICAL TISSUE IMPEDANCE PARAMETERS

Directory of Open Access Journals (Sweden)

V. I. Bankov

2016-01-01

Full Text Available Objective. Investigation the opportunity for measurement of biological tissue impedance to visualize its parameters.Materials and methods. Studies were undertook on the experimental facility, consists of registrating measuring cell, constructed from flat inductors system, formed in oscillatory circuit, herewith investigated biological tissue is the part of this oscillatory circuit. An excitation of oscillatory circuit fulfilled by means of exciter inductor which forms impulse complex modulated electromagnetic field (ICM EMF. The measurement process and visualizations provided by set of certificated instruments: a digital oscillograph AKTAKOM ADS-2221MV, a digital generator АКТАКОМ AWG-4150 (both with software and a gauge RLC E7-22. Comparative dynamic studies of fixed volume and weight pig’s blood, adipose tissue, muscular tissue impedance were conducted by contact versus contactless methods. Contactless method in contrast to contact method gives opportunity to obtain the real morphological visualization of biological tissue irrespective of their nature.Results. Comparison of contact and contactless methods of impedance measurement shows that the inductance to capacitance ratio X(L / X(C was equal: 17 – for muscular tissue, 4 – for blood, 1 – for adipose tissue. It demonstrates the technical correspondence of both impedance registration methods. If propose the base relevance of X (L and X (C parameters for biological tissue impedance so contactless measurement method for sure shows insulating properties of adipose tissue and high conductivity for blood and muscular tissue in fixed volume-weight parameters. Registration of biological tissue impedance complex parameters by contactless method with the help of induced ICM EMF in fixed volume of biological tissue uncovers the most important informative volumes to characterize morphofunctional condition of biological tissue namely X (L / X (C.Conclusion. Contactless method of biological

Patterns of database citation in articles and patents indicate long-term scientific and industry value of biological data resources [version 1; referees: 2 approved

Directory of Open Access Journals (Sweden)

David Bousfield

2016-02-01

Full Text Available Data from open access biomolecular data resources, such as the European Nucleotide Archive and the Protein Data Bank are extensively reused within life science research for comparative studies, method development and to derive new scientific insights. Indicators that estimate the extent and utility of such secondary use of research data need to reflect this complex and highly variable data usage. By linking open access scientific literature, via Europe PubMedCentral, to the metadata in biological data resources we separate data citations associated with a deposition statement from citations that capture the subsequent, long-term, reuse of data in academia and industry.  We extend this analysis to begin to investigate citations of biomolecular resources in patent documents. We find citations in more than 8,000 patents from 2014, demonstrating substantial use and an important role for data resources in defining biological concepts in granted patents to both academic and industrial innovators. Combined together our results indicate that the citation patterns in biomedical literature and patents vary, not only due to citation practice but also according to the data resource cited. The results guard against the use of simple metrics such as citation counts and show that indicators of data use must not only take into account citations within the biomedical literature but also include reuse of data in industry and other parts of society by including patents and other scientific and technical documents such as guidelines, reports and grant applications.

Information support of the processes of organizational management of the earth’s biological resources

Directory of Open Access Journals (Sweden)

Ovezgheldyiev А.О.

2016-04-01

Full Text Available The paper offers the classification of information and a brief description of all major organizations, institutions and communities involved in the study or solving problems of global warming, the preservation of the environment and ecology of the Earth's biosphere. All the organizations, institutions and communities are organized by statuses: international, regional, national, and others. Their information description specifies the name in Ukrainian and English languages, internet addresses, the number of member states, the location of the headquarters, the purpose and main activities, as well as the condition and status of relations with Ukraine. It is proposed to create a unified information database of all these agencies on the status of biological resources of our planet Earth. We considered the principal Ukraine's problems in biodiversity conservation and environmental protection for now.

NURE [National Uranium Resource Evaluation] HSSR [Hydrogeochemical and Stream Sediment Reconnaissance] Introduction to Data Files, United States: Volume 1

International Nuclear Information System (INIS)

1985-01-01

One product of the Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) program, a component of the National Uranium Resource Evaluation (NURE), is a data-base of interest to scientists and professionals in the academic, business, industrial, and governmental communities. This database contains individual records for water and sediment samples taken during the reconnaissance survey of the entire United States, excluding Hawaii. The purpose of this report is to describe the NURE HSSR data by highlighting its key characteristics and providing user guides to the data. A companion report, ''A Technical History of the NURE HSSR Program,'' summarizes those aspects of the HSSR Program which are likely to be important in helping users understand the database. Each record on the database contains varying information on general field or site characteristics and analytical results for elemental concentrations in the sample; the database is potentially valuable for describing the geochemistry of specified locations and addressing issues or questions in other areas such as water quality, geoexploration, and hydrologic studies. This report is organized in twelve volumes. This first volume presents a brief history of the NURE HSSR program, a description of the data files produced by ISP, a Users' Dictionary for the Analysis File and graphs showing the distribution of elemental concentrations for sediments at the US level. Volumes 2 through 12 are comprised of Data Summary Tables displaying the percentile distribution of the elemental concentrations on the file. Volume 2 contains data for the individual states. Volumes 3 through 12 contain data for the 1 0 x 2 0 quadrangles, organized into eleven regional files; the data for the two regional files for Alaska (North and South) are bound together as Volume 12

Forest resources of the United States, 1992

Science.gov (United States)

Douglas S. Powell; Joanne L. Faulkner; David R. Darr; Zhiliang Zhu; Douglas W. MacCleery

1993-01-01

The 1987 Resources Planning Act (RPA) Assessment forest resources statistics are updated to 1992, to provide current information on the Nation's forests. Resource tables present estimates of forest area, volume, mortality, growth, removals, and timber products output. Resource data are analyzed, and trends since 1987 are noted. A forest type map produced from...

Evolutionary Biology Research in India

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 10. Evolutionary Biology Research in India. Information and Announcements Volume 5 Issue 10 October 2000 pp 102-104. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/005/10/0102-0104 ...

MIPS Arabidopsis thaliana Database (MAtDB): an integrated biological knowledge resource based on the first complete plant genome

Science.gov (United States)

Schoof, Heiko; Zaccaria, Paolo; Gundlach, Heidrun; Lemcke, Kai; Rudd, Stephen; Kolesov, Grigory; Arnold, Roland; Mewes, H. W.; Mayer, Klaus F. X.

2002-01-01

Arabidopsis thaliana is the first plant for which the complete genome has been sequenced and published. Annotation of complex eukaryotic genomes requires more than the assignment of genetic elements to the sequence. Besides completing the list of genes, we need to discover their cellular roles, their regulation and their interactions in order to understand the workings of the whole plant. The MIPS Arabidopsis thaliana Database (MAtDB; http://mips.gsf.de/proj/thal/db) started out as a repository for genome sequence data in the European Scientists Sequencing Arabidopsis (ESSA) project and the Arabidopsis Genome Initiative. Our aim is to transform MAtDB into an integrated biological knowledge resource by integrating diverse data, tools, query and visualization capabilities and by creating a comprehensive resource for Arabidopsis as a reference model for other species, including crop plants. PMID:11752263

Biological Art of Producing Useful Chemicals

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 3. Metabolic Engineering: Biological Art of Producing Useful Chemicals. Ram Kulkarni. General Article Volume 21 Issue 3 March 2016 pp 233-237. Fulltext. Click here to view fulltext PDF. Permanent link:

1991 SOLAR WORLD CONGRESS - VOLUME 1, PART I

Science.gov (United States)

The four-volume proceedings document the 1991 Solar World Congress (the biennial congress of the International Solar Energy Society) in Denver, CO, August 19-23, 1991. Volume 1 is dedicated to solar electricity, biofuels, and renewable resources. Volume 2 contains papers on activ...

An Integrated Approach to Biology

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 8. An Integrated Approach to Biology. Aniket Bhattacharya. General Article Volume 16 Issue 8 August 2011 pp 742-753. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/016/08/0742-0753 ...

World uranium exploration, resources, production and related activities

International Nuclear Information System (INIS)

Hanly, A.

2014-01-01

A Nuclear Energy Series publication entitled “World Uranium Exploration, Resources, Production and Related Activities” (WUERPRA) will soon be published by the IAEA. The objective of the publication is to provide a comprehensive compilation of historic uranium exploration, resources, production and related activities based primarily on information from the 1966 to 2009 editions of the publication “Uranium Resources, Production and Demand”, a joint publication of the International Atomic Energy Agency and the Nuclear Energy Agency/Organization for Economic Cooperation and Development commonly known as the ‘Red Book’. This has been supplemented by historic information from other reliable sources. The publications also include, where enough information was available, descriptions of the relative potential for discovery of new uranium resources on a per country basis. To recover complete historic information it is frequently necessary to refer to earlier editions of the Red Book, many of which may not be readily available. This publication aims to provide one comprehensive source for much of this type of information which will reduce the effort required to prepare future editions of the Red Book, as well as make the historic Red Book information, together with select related information from other sources, more readily available to all users with an interest in uranium. WUERPRA comprises 6 volumes containing 164 country reports, each organized by region; Volume 1: Africa (53 countries); Volume 2: Central, Eastern and Southeastern Europe (25 countries); Volume 3: Southeastern Asia, Pacific, East Asia (18 countries); Volume 4: Western Europe (22 countries); Volume 5: Middle East, Central and Southern Asia (19 countries), and; Volume 6: North America, Central America and South America (27 countries). The report also contains information on countries that have not reported to the Red Book. The poster will summarize select major highlights from each volume

Introduction to Northeast Pacific Shark Biology, Ecology, and Conservation.

Science.gov (United States)

Lowry, Dayv; Larson, Shawn E

Sharks are iconic, sometimes apex, predators found in every ocean and, as a result, they have featured prominently in the mythology, history, and fisheries of diverse human cultures around the world. Because of their regional significance to fisheries and ecological role as predators, and as a result of concern over long-term stability of their populations, there has been an increasing amount of work focused on shark conservation in recent decades. This volume highlights the biodiversity and biological attributes of, and conservation efforts targeted at, populations of sharks that reside in the Northeast Pacific Ocean bordering the west coast of the United States and Canada, one of the most economically and ecologically important oceanic regions in the world. A companion volume addresses details of fisheries and ecotourism in the same region, as well as delving into the relationship between captive husbandry of sharks and education/outreach efforts aimed at fostering a conservation mindset in the public at large. Together, these volumes provide readers a detailed backdrop against which to consider their own actions, and those of resource managers, academics, and educators, as they relate to the long-term conservation of sharks and their relatives. © 2017 Elsevier Ltd. All rights reserved.

The Central Dogma of Molecular Biology

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 14; Issue 3. The Central Dogma of Molecular Biology - A Retrospective after Fifty Years. Michel Morange. General Article Volume 14 Issue 3 March 2009 pp 236-247. Fulltext. Click here to view fulltext PDF. Permanent link:

WE-B-304-03: Biological Treatment Planning

International Nuclear Information System (INIS)

Orton, C.

2015-01-01

The ultimate goal of radiotherapy treatment planning is to find a treatment that will yield a high tumor control probability (TCP) with an acceptable normal tissue complication probability (NTCP). Yet most treatment planning today is not based upon optimization of TCPs and NTCPs, but rather upon meeting physical dose and volume constraints defined by the planner. It has been suggested that treatment planning evaluation and optimization would be more effective if they were biologically and not dose/volume based, and this is the claim debated in this month’s Point/Counterpoint. After a brief overview of biologically and DVH based treatment planning by the Moderator Colin Orton, Joseph Deasy (for biological planning) and Charles Mayo (against biological planning) will begin the debate. Some of the arguments in support of biological planning include: this will result in more effective dose distributions for many patients DVH-based measures of plan quality are known to have little predictive value there is little evidence that either D95 or D98 of the PTV is a good predictor of tumor control sufficient validated outcome prediction models are now becoming available and should be used to drive planning and optimization Some of the arguments against biological planning include: several decades of experience with DVH-based planning should not be discarded we do not know enough about the reliability and errors associated with biological models the radiotherapy community in general has little direct experience with side by side comparisons of DVH vs biological metrics and outcomes it is unlikely that a clinician would accept extremely cold regions in a CTV or hot regions in a PTV, despite having acceptable TCP values Learning Objectives: To understand dose/volume based treatment planning and its potential limitations To understand biological metrics such as EUD, TCP, and NTCP To understand biologically based treatment planning and its potential limitations

A Physicist Looks at Biology

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 11. A Physicist Looks at Biology. Max Delbrück. Classics Volume 4 Issue 11 November 1999 pp 89-102. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/004/11/0089-0102. Author Affiliations.

Management, Resources and Reproductive Biology

Directory of Open Access Journals (Sweden)

Bernard Wallner

2014-10-01

Full Text Available This work presents a relationship between environmental conditions and reproductive performance in modern humans. Birth rates and sex ratio (SRB at birth were analyzed from large data scales. The results include data from people working or living under different job respectively socio-economic conditions, such as employees working in the academic field, employees under supervisory or hire and fire conditions, and people who have better access to resources. The results show that employees who have better jobs and earn more money do have more children and females under better socio-economic conditions do give birth to more sons. In conclusion, it is suggested that different socio-economic environmental conditions may have an impact on female and male birth rates and SRBs, which may be related to stress perception rates.

Optimisation of Investment Resources at Small Enterprises

Directory of Open Access Journals (Sweden)

Shvets Iryna B.

2014-03-01

Full Text Available The goal of the article lies in the study of the process of optimisation of the structure of investment resources, development of criteria and stages of optimisation of volumes of investment resources for small enterprises by types of economic activity. The article characterises the process of transformation of investment resources into assets and liabilities of the balances of small enterprises and conducts calculation of the structure of sources of formation of investment resources in Ukraine at small enterprises by types of economic activity in 2011. On the basis of the conducted analysis of the structure of investment resources of small enterprises the article forms main groups of criteria of optimisation in the context of individual small enterprises by types of economic activity. The article offers an algorithm and step-by-step scheme of optimisation of investment resources at small enterprises in the form of a multi-stage process of management of investment resources in the context of increase of their mobility and rate of transformation of existing resources into investments. The prospect of further studies in this direction is development of a structural and logic scheme of optimisation of volumes of investment resources at small enterprises.

Advances in radiation biology

International Nuclear Information System (INIS)

Lett, J.T.; Ehmann, U.K.; Cox, A.B.

1987-01-01

The classical period of radiation biology is coming to a close. Such change always occurs at a time when the ideas and concepts that promoted the burgeoning of an infant science are no longer adequate. This volume covers a number of areas in which new ideas and research are playing a vital role, including cellular radiation sensitivity, radioactive waste disposal, and space radiation biology

Nuclear magnetic resonance of biological macromolecules part A

CERN Document Server

Schmitz, Uli; Schmitz, Uli; Dotsch, Volker

2001-01-01

This volume and its companion, Volume 339, supplement Volumes 176, 177, 239, and 261. Chapters are written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules.

Water resources data, Idaho, 2004; Volume 1. Surface water records for Great Basin and Snake River basin above King Hill

Science.gov (United States)

Brennan, T.S.; Lehmann, A.K.; O'Dell, I.

2005-01-01

Water resources data for the 2004 water year for Idaho consists of records of stage, discharge, and water quality of streams; stage, contents, and water quality of lakes and reservoirs; discharge of irrigation diversions; and water levels and water quality of groundwater. The three volumes of this report contain discharge records for 209 stream-gaging stations and 8 irrigation diversions; stage only records for 6 stream-gaging stations; stage only for 6 lakes and reservoirs; contents only for 13 lakes and reservoirs; water-quality for 39 stream-gaging stations and partial record sites, 3 lakes sites, and 395 groundwater wells; and water levels for 425 observation network wells and 900 special project wells. Additional water data were collected at various sites not involved in the systematic data collection program and are published as miscellaneous measurements. Volumes 1 & 2 contain the surface-water and surface-water-quality records. Volume 3 contains the ground-water and ground-water-quality records. These data represent that part of the National Water Data System operated by the U.S. Geological Survey and cooperating State and Federal agencies in Idaho, adjacent States, and Canada.

Water resources data, Idaho, 2003; Volume 1. Surface water records for Great Basin and Snake River basin above King Hill

Science.gov (United States)

Brennan, T.S.; Lehmann, A.K.; O'Dell, I.

2004-01-01

Water resources data for the 2003 water year for Idaho consists of records of stage, discharge, and water quality of streams; stage, contents, and water quality of lakes and reservoirs; discharge of irrigation diversions; and water levels and water quality of groundwater. The three volumes of this report contain discharge records for 208 stream-gaging stations and 14 irrigation diversions; stage only records for 6 stream-gaging stations; stage only for 6 lakes and reservoirs; contents only for 13 lakes and reservoirs; water-quality for 50 stream-gaging stations and partial record sites, 3 lakes sites, and 398 groundwater wells; and water levels for 427 observation network wells and 900 special project wells. Additional water data were collected at various sites not involved in the systematic data collection program and are published as miscellaneous measurements. Volumes 1 & 2 contain the surface-water and surface-water-quality records. Volume 3 contains the ground-water and ground-water-quality records. These data represent that part of the National Water Data System operated by the U.S. Geological Survey and cooperating State and Federal agencies in Idaho, adjacent States, and Canada.

The Manila Declaration concerning the ethical utilization of Asian biological resources

NARCIS (Netherlands)

NN,

1992-01-01

— the maintenance of biological and cultural diversity is of global concern — developing countries are major centres of biological and cultural diversity — there is increased interest in biological material with medicinal and other economic values — indigenous peoples frequently possess knowledge

The role of domain-general cognitive resources in children's construction of a vitalist theory of biology.

Science.gov (United States)

Bascandziev, Igor; Tardiff, Nathan; Zaitchik, Deborah; Carey, Susan

2018-03-24

Some episodes of learning are easier than others. Preschoolers can learn certain facts, such as "my grandmother gave me this purse," only after one or two exposures (easy to learn; fast mapping), but they require several years to learn that plants are alive or that the sun is not alive (hard to learn). One difference between the two kinds of knowledge acquisition is that hard cases often require conceptual construction, such as the construction of the biological concept alive, whereas easy cases merely involve forming new beliefs formulated over concepts the child already has (belief revision, a form of knowledge enrichment). We asked whether different domain-general cognitive resources support these two types of knowledge acquisition (conceptual construction and knowledge enrichment that supports fast mapping) by testing 82 6-year-olds in a pre-training/training/post-training study. We measured children's improvement in an episode involving theory construction (the beginning steps of acquisition of the framework theory of vitalist biology, which requires conceptual change) and in an episode involving knowledge enrichment alone (acquisition of little known facts about animals, such as the location of crickets' ears and the color of octopus blood). In addition, we measured children's executive functions and receptive vocabulary to directly compare the resources drawn upon in the two episodes of learning. We replicated and extended previous findings highlighting the differences between conceptual construction and knowledge enrichment, and we found that Executive Functions predict improvement on the Vitalism battery but not on the Fun Facts battery and that Receptive Vocabulary predicts improvement the Fun Facts battery but not on the Vitalism battery. This double dissociation provides new evidence for the distinction between the two types of knowledge acquisition, and bears on the nature of the learning mechanisms involved in each. Copyright © 2018 Elsevier Inc. All

Scaffolded biology.

Science.gov (United States)

Minelli, Alessandro

2016-09-01

Descriptions and interpretations of the natural world are dominated by dichotomies such as organism vs. environment, nature vs. nurture, genetic vs. epigenetic, but in the last couple of decades strong dissatisfaction with those partitions has been repeatedly voiced and a number of alternative perspectives have been suggested, from perspectives such as Dawkins' extended phenotype, Turner's extended organism, Oyama's Developmental Systems Theory and Odling-Smee's niche construction theory. Last in time is the description of biological phenomena in terms of hybrids between an organism (scaffolded system) and a living or non-living scaffold, forming unit systems to study processes such as reproduction and development. As scaffold, eventually, we can define any resource used by the biological system, especially in development and reproduction, without incorporating it as happens in the case of resources fueling metabolism. Addressing biological systems as functionally scaffolded systems may help pointing to functional relationships that can impart temporal marking to the developmental process and thus explain its irreversibility; revisiting the boundary between development and metabolism and also regeneration phenomena, by suggesting a conceptual framework within which to investigate phenomena of regular hypermorphic regeneration such as characteristic of deer antlers; fixing a periodization of development in terms of the times at which a scaffolding relationship begins or is terminated; and promoting plant galls to legitimate study objects of developmental biology.

Science Academies' Refresher Course in Developmental Biology

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 8. Science Academies' Refresher Course in Developmental Biology. Information and Announcements Volume 20 Issue 8 August 2015 pp 756-756. Fulltext. Click here to view fulltext PDF. Permanent link:

Uranium resource processing. Secondary resources

International Nuclear Information System (INIS)

Gupta, C.K.; Singh, H.

2003-01-01

This book concentrates on the processing of secondary sources for recovering uranium, a field which has gained in importance in recent years as it is environmental-friendly and economically in tune with the philosophy of sustainable development. Special mention is made of rock phosphate, copper and gold tailings, uranium scrap materials (both natural and enriched) and sea water. This volume includes related area of ore mineralogy, resource classification, processing principles involved in solubilization followed by separation and safety aspects

Effects of reduced return activated sludge flows and volume on anaerobic zone performance for a septic wastewater biological phosphorus removal system.

Science.gov (United States)

Magro, Daniel; Elias, Steven L; Randall, Andrew Amis

2005-01-01

Enhanced biological phosphorous removal (EBPR) performance was found to be adequate with reduced return-activated sludge (RAS) flows (50% of available RAS) to the anaerobic tank and smaller-than-typical anaerobic zone volume (1.08 hours hydraulic retention time [HRT]). Three identical parallel biological nutrient removal pilot plants were fed with strong, highly fermented (160 mg/L volatile fatty acids [VFAs]), domestic and industrial wastewater from a full-scale wastewater treatment facility. The pilot plants were operated at 100, 50, 40, and 25% RAS (percent of available RAS) flows to the anaerobic tank, with the remaining RAS to the anoxic tank. In addition, varying anaerobic HRT (1.08 and 1.5 hours) and increased hydraulic loading (35% increase) were examined. The study was divided into four phases, and the effect of these process variations on EBPR were studied by having one different variable between two identical systems. The most significant conclusion was that returning part of the RAS to the anaerobic zone did not decrease EBPR performance; instead, it changed the location of phosphorous release and uptake. Bringing less RAS to the anaerobic and more to the anoxic tank decreased anaerobic phosphorus release and increased anoxic phosphorus release (or decreased anoxic phosphorus uptake). Equally important is that, with VFA-rich influent wastewater, excessive anaerobic volume was shown to hurt overall phosphorus removal, even when it resulted in increased anaerobic phosphorus release.

Creating Successful Campus Partnerships for Teaching Communication in Biology Courses and Labs.

Science.gov (United States)

Hall, Susanne E; Birch, Christina

2018-01-01

Creating and teaching successful writing and communication assignments for biology undergraduate students can be challenging for faculty trying to balance the teaching of technical content. The growing body of published research and scholarship on effective teaching of writing and communication in biology can help inform such work, but there are also local resources available to support writing within biology courses that may be unfamiliar to science faculty and instructors. In this article, we discuss common on-campus resources biology faculty can make use of when incorporating writing and communication into their teaching. We present the missions, histories, and potential collaboration outcomes of three major on-campus writing resources: writing across the curriculum and writing in the disciplines initiatives (WAC/WID), writing programs, and writing centers. We explain some of the common misconceptions about these resources in order to help biology faculty understand their uses and limits, and we offer guiding questions faculty might ask the directors of these resources to start productive conversations. Collaboration with these resources will likely save faculty time and effort on curriculum development and, more importantly, will help biology students develop and improve their critical reading, writing, and communication skills.

Solid waste as a renewable resource

NARCIS (Netherlands)

Faria Albanese, Jimmy Alexander; Ruiz, M. Pilar

2016-01-01

The volume of waste produced by human activity continues to grow, but steps are being taken to mitigate this problem by viewing waste as a resource. Recovering a proportion of waste for re-use immediately reduces the volume of landfill. Furthermore, the scarcity of some elements (such as phosphorous

Hawaii Geothermal Project annotated bibliography: Biological resources of the geothermal subzones, the transmission corridors and the Puna District, Island of Hawaii

Energy Technology Data Exchange (ETDEWEB)

Miller, S.E.; Burgett, J.M. [Fish and Wildlife Service, Honolulu, HI (United States). Pacific Islands Office

1993-10-01

Task 1 of the Hawaii Geothermal Project Interagency Agreement between the Fish and Wildlife Service and the Department of Energy-Oak Ridge National Laboratory (DOE) includes an annotated bibliography of published and unpublished documents that cover biological issues related to the lowland rain forest in Puna, adjacent areas, transmission corridors, and in the proposed Hawaii Geothermal Project (HGP). The 51 documents reviewed in this report cover the main body of biological information for these projects. The full table of contents and bibliography for each document is included along with two copies (as requested in the Interagency Agreement) of the biological sections of each document. The documents are reviewed in five main categories: (1) geothermal subzones (29 documents); (2) transmission cable routes (8 documents); (3) commercial satellite launching facility (Spaceport; 1 document); (4) manganese nodule processing facility (2 documents); (5) water resource development (1 document); and (6) ecosystem stability and introduced species (11 documents).

Electromagnetic fields in biological systems

National Research Council Canada - National Science Library

Lin, James C

2012-01-01

"Focusing on exposure, induced fields, and absorbed energy, this volume covers the interaction of electromagnetic fields and waves with biological systems, spanning static fields to terahertz waves...

Opportunities in plant synthetic biology.

Science.gov (United States)

Cook, Charis; Martin, Lisa; Bastow, Ruth

2014-05-01

Synthetic biology is an emerging field uniting scientists from all disciplines with the aim of designing or re-designing biological processes. Initially, synthetic biology breakthroughs came from microbiology, chemistry, physics, computer science, materials science, mathematics, and engineering disciplines. A transition to multicellular systems is the next logical step for synthetic biologists and plants will provide an ideal platform for this new phase of research. This meeting report highlights some of the exciting plant synthetic biology projects, and tools and resources, presented and discussed at the 2013 GARNet workshop on plant synthetic biology.

First Biomass Conference of the Americas: Energy, environment, agriculture, and industry; Proceedings, Volume 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-10-01

This conference was designed to provide a national and international forum to support the development of a viable biomass industry. Although papers on research activities and technologies under development that address industry problems comprised part of this conference, an effort was made to focus on scale-up and demonstration projects, technology transfer to end users, and commercial applications of biomass and wastes. The conference was divided into these major subject areas: Resource Base, Power Production, Transportation Fuels, Chemicals and Products, Environmental Issues, Commercializing Biomass Projects, Biomass Energy System Studies, and Biomass in Latin America. The papers in this first volume deal with Resource Base and Power Production. The particular subjects within the Resource Base area are Biomass, Wastes and Residues, Feedstock Research, and Commercial Systems. The emphasized subjects within the Power Production area are Combustion, Thermal and Biological Gasification, Waste Generation and Waste Disposal and Waste Emissions, and Heat, Steam, and Fuels-Commercial Systems. Selected abstracts have been indexed separately for inclusion in the Energy Science and Technology Database.

An ontology-driven semantic mashup of gene and biological pathway information: application to the domain of nicotine dependence.

Science.gov (United States)

Sahoo, Satya S; Bodenreider, Olivier; Rutter, Joni L; Skinner, Karen J; Sheth, Amit P

2008-10-01

This paper illustrates how Semantic Web technologies (especially RDF, OWL, and SPARQL) can support information integration and make it easy to create semantic mashups (semantically integrated resources). In the context of understanding the genetic basis of nicotine dependence, we integrate gene and pathway information and show how three complex biological queries can be answered by the integrated knowledge base. We use an ontology-driven approach to integrate two gene resources (Entrez Gene and HomoloGene) and three pathway resources (KEGG, Reactome and BioCyc), for five organisms, including humans. We created the Entrez Knowledge Model (EKoM), an information model in OWL for the gene resources, and integrated it with the extant BioPAX ontology designed for pathway resources. The integrated schema is populated with data from the pathway resources, publicly available in BioPAX-compatible format, and gene resources for which a population procedure was created. The SPARQL query language is used to formulate queries over the integrated knowledge base to answer the three biological queries. Simple SPARQL queries could easily identify hub genes, i.e., those genes whose gene products participate in many pathways or interact with many other gene products. The identification of the genes expressed in the brain turned out to be more difficult, due to the lack of a common identification scheme for proteins. Semantic Web technologies provide a valid framework for information integration in the life sciences. Ontology-driven integration represents a flexible, sustainable and extensible solution to the integration of large volumes of information. Additional resources, which enable the creation of mappings between information sources, are required to compensate for heterogeneity across namespaces. RESOURCE PAGE: http://knoesis.wright.edu/research/lifesci/integration/structured_data/JBI-2008/

SEEK: a systems biology data and model management platform.

Science.gov (United States)

Wolstencroft, Katherine; Owen, Stuart; Krebs, Olga; Nguyen, Quyen; Stanford, Natalie J; Golebiewski, Martin; Weidemann, Andreas; Bittkowski, Meik; An, Lihua; Shockley, David; Snoep, Jacky L; Mueller, Wolfgang; Goble, Carole

2015-07-11

Systems biology research typically involves the integration and analysis of heterogeneous data types in order to model and predict biological processes. Researchers therefore require tools and resources to facilitate the sharing and integration of data, and for linking of data to systems biology models. There are a large number of public repositories for storing biological data of a particular type, for example transcriptomics or proteomics, and there are several model repositories. However, this silo-type storage of data and models is not conducive to systems biology investigations. Interdependencies between multiple omics datasets and between datasets and models are essential. Researchers require an environment that will allow the management and sharing of heterogeneous data and models in the context of the experiments which created them. The SEEK is a suite of tools to support the management, sharing and exploration of data and models in systems biology. The SEEK platform provides an access-controlled, web-based environment for scientists to share and exchange data and models for day-to-day collaboration and for public dissemination. A plug-in architecture allows the linking of experiments, their protocols, data, models and results in a configurable system that is available 'off the shelf'. Tools to run model simulations, plot experimental data and assist with data annotation and standardisation combine to produce a collection of resources that support analysis as well as sharing. Underlying semantic web resources additionally extract and serve SEEK metadata in RDF (Resource Description Format). SEEK RDF enables rich semantic queries, both within SEEK and between related resources in the web of Linked Open Data. The SEEK platform has been adopted by many systems biology consortia across Europe. It is a data management environment that has a low barrier of uptake and provides rich resources for collaboration. This paper provides an update on the functions and

Towards multidimensional radiotherapy (MD-CRT): biological imaging and biological conformality

International Nuclear Information System (INIS)

Ling, C. Clifton; Humm, John; Larson, Steven; Amols, Howard; Fuks, Zvi; Leibel, Steven; Koutcher, Jason A.

2000-01-01

Purpose: The goals of this study were to survey and summarize the advances in imaging that have potential applications in radiation oncology, and to explore the concept of integrating physical and biological conformality in multidimensional conformal radiotherapy (MD-CRT). Methods and Materials: The advances in three-dimensional conformal radiotherapy (3D-CRT) have greatly improved the physical conformality of treatment planning and delivery. The development of intensity-modulated radiotherapy (IMRT) has provided the 'dose painting' or 'dose sculpting' ability to further customize the delivered dose distribution. The improved capabilities of nuclear magnetic resonance imaging and spectroscopy, and of positron emission tomography, are beginning to provide physiological and functional information about the tumor and its surroundings. In addition, molecular imaging promises to reveal tumor biology at the genotype and phenotype level. These developments converge to provide significant opportunities for enhancing the success of radiotherapy. Results: The ability of IMRT to deliver nonuniform dose patterns by design brings to fore the question of how to 'dose paint' and 'dose sculpt', leading to the suggestion that 'biological' images may be of assistance. In contrast to the conventional radiological images that primarily provide anatomical information, biological images reveal metabolic, functional, physiological, genotypic, and phenotypic data. Important for radiotherapy, the new and noninvasive imaging methods may yield three-dimensional radiobiological information. Studies are urgently needed to identify genotypes and phenotypes that affect radiosensitivity, and to devise methods to image them noninvasively. Incremental to the concept of gross, clinical, and planning target volumes (GTV, CTV, and PTV), we propose the concept of 'biological target volume' (BTV) and hypothesize that BTV can be derived from biological images and that their use may incrementally improve

Wind energy resource atlas. Volume 7. The south central region

Energy Technology Data Exchange (ETDEWEB)

Edwards, R.L.; Graves, L.F.; Sprankle, A.C.; Elliott, D.L.; Barchet, W.R.; George, R.L.

1981-03-01

This atlas of the south central region combines seven collections of wind resource data: one for the region, and one for each of the six states (Arkansas, Kansas, Louisiana, Missouri, Oklahoma, and Texas). At the state level, features of the climate, topography, and wind resource are discussed in greater detail than that provided in the regional discussion, and the data locations on which the assessment is based are mapped. Variations, over several time scales, in the wind resource at selected stations in each state are shown on graphs of monthly average and interannual wind speed and power, and hourly average wind speed for each season. Other graphs present speed, direction, and duration frequencies of the wind at these locations.

Programme Biology - Health protection

International Nuclear Information System (INIS)

1975-01-01

The scientific results for 1975, of the five-year Biology-Health Protection programme adopted in 1971, are presented in two volumes. In volume one, Research in Radiation Protection are developed exclusively, including the following topics: measurement and interpretation of radiation (dosimetry); transfer of radioactive nuclides in the constituents of the environment; hereditary effects of radiation; short-term effects (acute irradiation syndrome and its treatment); long-term effects and toxicology of radioactive elements. In volume, two Research on applications in Agriculture and Medicine are developed. It includes: mutagenesis; soil-plant relations; radiation analysis; food conservation; cell culture; radioentomology. Research on applications in Medicine include: Nuclear Medicine and Neutron Dosimetry

Research resources for Drosophila: the expanding universe.

Science.gov (United States)

Matthews, Kathleen A; Kaufman, Thomas C; Gelbart, William M

2005-03-01

Drosophila melanogaster has been the subject of research into central questions about biological mechanisms for almost a century. The experimental tools and resources that are available or under development for D. melanogaster and its related species, particularly those for genomic analysis, are truly outstanding. Here we review three types of resource that have been developed for D. melanogaster research: databases and other sources of information, biological materials and experimental services. These resources are there to be exploited and we hope that this guide will encourage new uses for D. melanogaster information, materials and services, both by those new to flies and by experienced D. melanogaster researchers.

Computational aspects of systematic biology.

Science.gov (United States)

Lilburn, Timothy G; Harrison, Scott H; Cole, James R; Garrity, George M

2006-06-01

We review the resources available to systematic biologists who wish to use computers to build classifications. Algorithm development is in an early stage, and only a few examples of integrated applications for systematic biology are available. The availability of data is crucial if systematic biology is to enter the computer age.

An ontology-driven semantic mash-up of gene and biological pathway information: Application to the domain of nicotine dependence

Science.gov (United States)

Sahoo, Satya S.; Bodenreider, Olivier; Rutter, Joni L.; Skinner, Karen J.; Sheth, Amit P.

2008-01-01

Objectives This paper illustrates how Semantic Web technologies (especially RDF, OWL, and SPARQL) can support information integration and make it easy to create semantic mashups (semantically integrated resources). In the context of understanding the genetic basis of nicotine dependence, we integrate gene and pathway information and show how three complex biological queries can be answered by the integrated knowledge base. Methods We use an ontology-driven approach to integrate two gene resources (Entrez Gene and HomoloGene) and three pathway resources (KEGG, Reactome and BioCyc), for five organisms, including humans. We created the Entrez Knowledge Model (EKoM), an information model in OWL for the gene resources, and integrated it with the extant BioPAX ontology designed for pathway resources. The integrated schema is populated with data from the pathway resources, publicly available in BioPAX-compatible format, and gene resources for which a population procedure was created. The SPARQL query language is used to formulate queries over the integrated knowledge base to answer the three biological queries. Results Simple SPARQL queries could easily identify hub genes, i.e., those genes whose gene products participate in many pathways or interact with many other gene products. The identification of the genes expressed in the brain turned out to be more difficult, due to the lack of a common identification scheme for proteins. Conclusion Semantic Web technologies provide a valid framework for information integration in the life sciences. Ontology-driven integration represents a flexible, sustainable and extensible solution to the integration of large volumes of information. Additional resources, which enable the creation of mappings between information sources, are required to compensate for heterogeneity across namespaces. Resource page http://knoesis.wright.edu/research/lifesci/integration/structured_data/JBI-2008/ PMID:18395495

Proceedings of the second United Nations symposium on the development and use of geothermal resources held at San Francisco, California, May 20--29, 1975. Volume 1

Energy Technology Data Exchange (ETDEWEB)

1976-01-01

The 299 papers in the Proceedings are presented in three volumes and are divided into twelve sections, each section dealing with a different aspect of geothermal energy. Rapporturs' summaries of the contents of each section are grouped together in Vol. 1 of the Proceedings; a separate abstract was prepared for each summary. Volume 1 also contains ninety-eight papers under the following section headings: present status of resources development; geology, hydrology, and geothermal systems; and geochemical techniques in exploration. Separate abstracts were prepared for ninety-seven papers. One paper was previously abstracted for ERA and appeared as CONF-750525--17. (LBS)

Space Synthetic Biology (SSB)

Data.gov (United States)

National Aeronautics and Space Administration — This project focused on employing advanced biological engineering and bioelectrochemical reactor systems to increase life support loop closure and in situ resource...

Optimization of total arc degree for stereotactic radiotherapy by using integral biologically effective dose and irradiated volume

International Nuclear Information System (INIS)

Lim, Do Hoon; Kim, Dae Yong; Lee, Myung Za; Chun, Ha Chung

2001-01-01

To find the optimal values of total arc degree to protect the normal brain tissue from high dose radiation in stereotactic radiotherapy planning. With Xknife-3 planning system and 4 MV linear accelerator, the authors planned under various values of parameters. One isocenter, 12, 20, 30, 40, 50, and 60 mm of collimator diameters, 100 deg, 200 deg, 300 deg, 400 deg, 500 deg, 600 deg, of total arc degrees, and 30 deg or 45 deg of arc intervals were used. After the completion of planning, the plans were compared each other using V 50 (the volume of normal brain that is delivered high dose radiation) and integral biologically effective dose. At 30 deg of arc interval, the values of V 50 had the decreased pattern with the increase of total arc degree in any collimator diameter. At 45 deg arc interval, up to 400 deg of total arc degree, the values of V 50 decreased with the increase of total arc degree, but at 500 deg and 600 deg of total arc degrees, the values increased. At 30 deg of arc interval, integral biologically effective dose showed the decreased pattern with the increase of total arc degree in any collimator diameter. At 45 deg arc interval with less than 40 mm collimator diameter, the integral biologically effective dose decreased with the increase of total arc degree, but with 50 and 60 mm of collimator diameters, up to 400 deg of total arc degree, integral biologically effective dose decreased with the increase of total arc degree, but at 500 deg and 600 deg of total arc degrees, the values increased. In the stereotactic radiotherapy planning for brain lesions, planning with 400 deg of total arc degree is optimal. Especially, when the larger collimator more than 50 mm diameter should be used, the uses of 500 deg and 600 deg of total arc degrees make the increase of V 50 and integral biologically effective dose, Therefore stereotactic radiotherapy planning using 400 deg of total arc degree can increase the therapeutic ratio and produce the effective outcome

Mineral resources potential of Antarctica

National Research Council Canada - National Science Library

Splettstoesser, John F; Dreschhoff, Gisela A. M

1990-01-01

.... This volume of the Antarctic Research Series results from an attempt to assemble a summary of current factual knowledge and scientific data related to issues of mineral resources in Antarctica...

Low-rank coal study : national needs for resource development. Volume 2. Resource characterization

Energy Technology Data Exchange (ETDEWEB)

1980-11-01

Comprehensive data are presented on the quantity, quality, and distribution of low-rank coal (subbituminous and lignite) deposits in the United States. The major lignite-bearing areas are the Fort Union Region and the Gulf Lignite Region, with the predominant strippable reserves being in the states of North Dakota, Montana, and Texas. The largest subbituminous coal deposits are in the Powder River Region of Montana and Wyoming, The San Juan Basin of New Mexico, and in Northern Alaska. For each of the low-rank coal-bearing regions, descriptions are provided of the geology; strippable reserves; active and planned mines; classification of identified resources by depth, seam thickness, sulfur content, and ash content; overburden characteristics; aquifers; and coal properties and characteristics. Low-rank coals are distinguished from bituminous coals by unique chemical and physical properties that affect their behavior in extraction, utilization, or conversion processes. The most characteristic properties of the organic fraction of low-rank coals are the high inherent moisture and oxygen contents, and the correspondingly low heating value. Mineral matter (ash) contents and compositions of all coals are highly variable; however, low-rank coals tend to have a higher proportion of the alkali components CaO, MgO, and Na/sub 2/O. About 90% of the reserve base of US low-rank coal has less than one percent sulfur. Water resources in the major low-rank coal-bearing regions tend to have highly seasonal availabilities. Some areas appear to have ample water resources to support major new coal projects; in other areas such as Texas, water supplies may be constraining factor on development.

Timberland resources of the Kenai Peninsula, Alaska, 1987.

Science.gov (United States)

Willem W.S. van Hees; Frederic R. Larson

1991-01-01

The 1987 inventory of the forest resources of the Kenai Peninsula was designed to assess the impact of the spruce beetle (Dendroctonus rufipennis (Kirby)) on the timberland component of the forest resource. Estimates of timberland area, volumes of timber, and growth and mortality of timber were developed. These estimates of timber resource...

Evolution and applications of plant pathway resources and databases

DEFF Research Database (Denmark)

Sucaet, Yves; Deva, Taru

2011-01-01

Plants are important sources of food and plant products are essential for modern human life. Plants are increasingly gaining importance as drug and fuel resources, bioremediation tools and as tools for recombinant technology. Considering these applications, database infrastructure for plant model...... systems deserves much more attention. Study of plant biological pathways, the interconnection between these pathways and plant systems biology on the whole has in general lagged behind human systems biology. In this article we review plant pathway databases and the resources that are currently available...

Identifying ELIXIR Core Data Resources [version 1; referees: 2 approved

Directory of Open Access Journals (Sweden)

Christine Durinx

2016-09-01

Full Text Available The core mission of ELIXIR is to build a stable and sustainable infrastructure for biological information across Europe. At the heart of this are the data resources, tools and services that ELIXIR offers to the life-sciences community, providing stable and sustainable access to biological data. ELIXIR aims to ensure that these resources are available long-term and that the life-cycles of these resources are managed such that they support the scientific needs of the life-sciences, including biological research. ELIXIR Core Data Resources are defined as a set of European data resources that are of fundamental importance to the wider life-science community and the long-term preservation of biological data. They are complete collections of generic value to life-science, are considered an authority in their field with respect to one or more characteristics, and show high levels of scientific quality and service. Thus, ELIXIR Core Data Resources are of wide applicability and usage. This paper describes the structures, governance and processes that support the identification and evaluation of ELIXIR Core Data Resources. It identifies key indicators which reflect the essence of the definition of an ELIXIR Core Data Resource and support the promotion of excellence in resource development and operation. It describes the specific indicators in more detail and explains their application within ELIXIR’s sustainability strategy and science policy actions, and in capacity building, life-cycle management and technical actions. Establishing the portfolio of ELIXIR Core Data Resources and ELIXIR Services is a key priority for ELIXIR and publicly marks the transition towards a cohesive infrastructure.

Discussion on water resources value accounting and its application

Science.gov (United States)

Guo, Biying; Huang, Xiaorong; Ma, Kai; Gao, Linyun; Wang, Yanqiu

2018-06-01

The exploration of the compilation of natural resources balance sheet has been proposed since 2013. Several elements of water resources balance sheet have been discussed positively in China, including basic concept, framework and accounting methods, which focused on calculating the amount of water resources with statistical methods but lacked the analysis of the interrelationship between physical volume and magnitude of value. Based on the study of physical accounting of water resources balance sheet, the connotation of water resources value is analyzed in combination with research on the value of water resources in the world. What's more, the theoretical framework, form of measurement and research methods of water resources value accounting are further explored. Taking Chengdu, China as an example, the index system of water resources balance sheet in Chengdu which includes both physical and valuable volume is established to account the depletion of water resources, environmental damage and ecological water occupation caused by economic and social water use. Moreover, the water resources balance sheet in this region which reflects the negative impact of the economy on the environment is established. It provides a reference for advancing water resources management, improving government and social investment, realizing scientific and rational allocation of water resources.

WE-B-304-00: Point/Counterpoint: Biological Dose Optimization

International Nuclear Information System (INIS)

2015-01-01

The ultimate goal of radiotherapy treatment planning is to find a treatment that will yield a high tumor control probability (TCP) with an acceptable normal tissue complication probability (NTCP). Yet most treatment planning today is not based upon optimization of TCPs and NTCPs, but rather upon meeting physical dose and volume constraints defined by the planner. It has been suggested that treatment planning evaluation and optimization would be more effective if they were biologically and not dose/volume based, and this is the claim debated in this month’s Point/Counterpoint. After a brief overview of biologically and DVH based treatment planning by the Moderator Colin Orton, Joseph Deasy (for biological planning) and Charles Mayo (against biological planning) will begin the debate. Some of the arguments in support of biological planning include: this will result in more effective dose distributions for many patients DVH-based measures of plan quality are known to have little predictive value there is little evidence that either D95 or D98 of the PTV is a good predictor of tumor control sufficient validated outcome prediction models are now becoming available and should be used to drive planning and optimization Some of the arguments against biological planning include: several decades of experience with DVH-based planning should not be discarded we do not know enough about the reliability and errors associated with biological models the radiotherapy community in general has little direct experience with side by side comparisons of DVH vs biological metrics and outcomes it is unlikely that a clinician would accept extremely cold regions in a CTV or hot regions in a PTV, despite having acceptable TCP values Learning Objectives: To understand dose/volume based treatment planning and its potential limitations To understand biological metrics such as EUD, TCP, and NTCP To understand biologically based treatment planning and its potential limitations

Wind Energy Resource Atlas. Volume 11. Hawaii and Pacific Islands Region

Energy Technology Data Exchange (ETDEWEB)

Schroeder, T.A.; Hori, A.M.; Elliott, D.L.; Barchet, W.R.; George, R.L.

1981-02-01

This atlas of the wind energy resource is composed of introductory and background information, and assessments of the wind resource in each division of the region. Background on how the wind resource is assessed and on how the results of the assessment should be inerpreted is presented. An introduction and outline to the descriptions of the wind resource for each division are provided. Assessments for individual divisions are presented as separate chapters. Much of the information in the division chapters is given in graphic or tabular form. The sequences for each chapter are similar, but some presentations used for Hawaii are inappropriate or impractical for presentation with the Pacific Islands. Hawaii chapter figure and tables are cited below and appropriate Pacific Islands figure and table numbers are included in brackets ().

Other relevant biological papers

International Nuclear Information System (INIS)

Shimizu, M.

1989-01-01

A considerable number of CRESP-relevant papers concerning deep-sea biology and radioecology have been published. It is the purpose of this study to call attention to them. They fall into three general categories. The first is papers of general interest. They are mentioned only briefly, and include text references to the global bibliography at the end of the volume. The second are papers that are not only mentioned and referenced, but for various reasons are described in abstract form. The last is a list of papers compiled by H.S.J. Roe specifically for this volume. They are listed in bibliographic form, and are also included in the global bibliography at the end of the volume

Design for volume reduction

NARCIS (Netherlands)

Wever, R.; Boks, C.; Stevels, A.

2007-01-01

Traditionally packaging design-for-sustainability (DfS) strongly focuses on resource conservation and material recycling. The type and amount of materials used has been the driver in design. For consumer electronics (CE) products this weight-based approach is too limited; a volume-based approach is

Health-related quality of life of Portuguese children and adolescents according to their biological maturation and volume of physical activity.

Science.gov (United States)

Garcia, Catarina; Teles, Júlia; Barrigas, Carlos; Fragoso, Isabel

2018-06-01

The purpose of this study was to analyze the relationship between biological maturation and health-related quality of life (HRQoL) in Portuguese children and adolescents of both sexes when the effect of chronological age (CA) and volume of physical activity (VPA) were removed. HRQoL, biological maturation, CA, and VPA were assessed in 750 children and adolescents, 11-17 years old, from 3 schools in Lisbon, Portugal. The KIDSCREEN-52 was used to assess HRQoL. Maturity indicator was bone age (BA), using Tanner-Whitehouse III method (TW3). The participants were classified into three different maturity categories: late, on time, and early maturers. VPA was assessed by questionnaire (RAPIL II). An analysis of covariance (ANCOVA), using the CA and the VPA as covariates was completed. The level of significance was set at p ≤ 0.05. Analysis of covariance suggested an influence of biological maturation in physical well-being dimension in both sexes, with early-maturing girls and boys having worst perception. Maturity groups were also influent in moods and emotions for girls. CA seems to be particularly important in self-perception and parent relation and home life for girls and in school environment for boys. Biological maturation and CA have relevant impact on some HRQoL dimensions. These variables, due to their nature and effect should be considered particularly when working with specific domains of HRQoL as physical well-being in both sexes, moods and emotions and self-perception and parent relation and home life for girls and in school environment for boys.

Water resources data, Iowa, water year 2001, Volume 2. surface water--Missouri River basin, and ground water

Science.gov (United States)

Nalley, G.M.; Gorman, J.G.; Goodrich, R.D.; Miller, V.E.; Turco, M.J.; Linhart, S.M.

2002-01-01

The Water Resources Division of the U.S. Geological Survey, in cooperation with State, county, municipal, and other Federal agencies, obtains a large amount of data pertaining to the water resources of Iowa each water year. These data, accumulated during many water years, constitute a valuable data base for developing an improved understanding of the water resources of the State. To make this data readily available to interested parties outside of the Geological Survey, the data is published annually in this report series entitled “Water Resources Data - Iowa” as part of the National Water Data System. Water resources data for water year 2001 for Iowa consists of records of stage, discharge, and water quality of streams; stage and contents of lakes and reservoirs; and water levels and water quality of ground water. This report, in two volumes, contains stage or discharge records for 132 gaging stations; stage records for 9 lakes and reservoirs; water-quality records for 4 gaging stations; sediment records for 13 gaging stations; and water levels for 163 ground-water observation wells. Also included are peak-flow data for 92 crest-stage partial-record stations, water-quality data from 86 municipal wells, and precipitation data collected at 6 gaging stations and 2 precipitation sites. Additional water data were collected at various sites not included in the systematic data-collection program, and are published here as miscellaneous measurements and analyses. These data represent that part of the National Water Data System operated by the U.S. Geological Survey and cooperating local, State, and Federal agencies in Iowa.Records of discharge or stage of streams, and contents or stage of lakes and reservoirs were first published in a series of U.S. Geological Survey water-supply papers entitled “Surface Water Supply of the United States.” Through September 30, 1960, these water-supply papers were published in an annual series; during 1961-65 and 1966-70, they

Municipal Solid Waste Resources

Energy Technology Data Exchange (ETDEWEB)

None

2016-06-01

Municipal solid waste (MSW) is a source of biomass material that can be utilized for bioenergy production with minimal additional inputs. MSW resources include mixed commercial and residential garbage such as yard trimmings, paper and paperboard, plastics, rubber, leather, textiles, and food wastes. Waste resources such as landfill gas, mill residues, and waste grease are already being utilized for cost-effective renewable energy generation. MSW for bioenergy also represents an opportunity to divert greater volumes of residential and commercial waste from landfills.

Managing biological diversity

Science.gov (United States)

Samson, Fred B.; Knopf, Fritz L.

1993-01-01

Biological diversity is the variety of life and accompanying ecological processes (Off. Technol. Assess. 1987, Wilcove and Samson 1987, Keystone 1991). Conservation of biological diversity is a major environmental issue (Wilson 1988, Counc. Environ. Quality 1991). The health and future of the earth's ecological systems (Lubchenco et al. 1991), global climate change (Botkin 1990), and an ever-increasing rate in loss of species, communities, and ecological systems (Myers 1990) are among issues drawing biological diversity to the mainstream of conservation worldwide (Int. Union Conserv. Nat. and Nat. Resour. [IUCN] et al. 1991). The legal mandate for conserving biological diversity is now in place (Carlson 1988, Doremus 1991). More than 19 federal laws govern the use of biological resources in the United States (Rein 1991). The proposed National Biological Diversity Conservation and Environmental Research Act (H.R. 585 and S.58) notes the need for a national biological diversity policy, would create a national center for biological diversity research, and recommends a federal interagency strategy for ecosystem conservation. There are, however, hard choices ahead for the conservation of biological diversity, and biologists are grappling with how to set priorities in research and management (Roberts 1988). We sense disillusion among field biologists and managers relative to how to operationally approach the seemingly overwhelming charge of conserving biological diversity. Biologists also need to respond to critics like Hunt (1991) who suggest a tree farm has more biological diversity than an equal area of old-growth forest. At present, science has played only a minor role in the conservation of biological diversity (Weston 1992) with no unified approach available to evaluate strategies and programs that address the quality and quantity of biological diversity (Murphy 1990, Erwin 1992). Although actions to conserve biological diversity need to be clearly defined by

Gulf Coast geopressured-geothermal program summary report compilation. Volume 2-A: Resource description, program history, wells tested, university and company based research, site restoration

Energy Technology Data Exchange (ETDEWEB)

John, C.J.; Maciasz, G.; Harder, B.J.

1998-06-01

The US Department of Energy established a geopressured-geothermal energy program in the mid 1970`s as one response to America`s need to develop alternate energy resources in view of the increasing dependence on imported fossil fuel energy. This program continued for 17 years and approximately two hundred million dollars were expended for various types of research and well testing to thoroughly investigate this alternative energy source. This volume describes the following studies: Geopressured-geothermal resource description; Resource origin and sediment type; Gulf Coast resource extent; Resource estimates; Project history; Authorizing legislation; Program objectives; Perceived constraints; Program activities and structure; Well testing; Program management; Program cost summary; Funding history; Resource characterization; Wells of opportunity; Edna Delcambre No. 1 well; Edna Delcambre well recompletion; Fairfax Foster Sutter No. 2 well; Beulah Simon No. 2 well; P.E. Girouard No. 1 well; Prairie Canal No. 1 well; Crown Zellerbach No. 2 well; Alice C. Plantation No. 2 well; Tenneco Fee N No. 1 well; Pauline Kraft No. 1 well; Saldana well No. 2; G.M. Koelemay well No. 1; Willis Hulin No. 1 well; Investigations of other wells of opportunity; Clovis A. Kennedy No. 1 well; Watkins-Miller No. 1 well; Lucien J. Richard et al No. 1 well; and the C and K-Frank A. Godchaux, III, well No. 1.

Identifying ELIXIR Core Data Resources [version 2; referees: 2 approved

Directory of Open Access Journals (Sweden)

Christine Durinx

2017-03-01

Full Text Available The core mission of ELIXIR is to build a stable and sustainable infrastructure for biological information across Europe. At the heart of this are the data resources, tools and services that ELIXIR offers to the life-sciences community, providing stable and sustainable access to biological data. ELIXIR aims to ensure that these resources are available long-term and that the life-cycles of these resources are managed such that they support the scientific needs of the life-sciences, including biological research. ELIXIR Core Data Resources are defined as a set of European data resources that are of fundamental importance to the wider life-science community and the long-term preservation of biological data. They are complete collections of generic value to life-science, are considered an authority in their field with respect to one or more characteristics, and show high levels of scientific quality and service. Thus, ELIXIR Core Data Resources are of wide applicability and usage. This paper describes the structures, governance and processes that support the identification and evaluation of ELIXIR Core Data Resources. It identifies key indicators which reflect the essence of the definition of an ELIXIR Core Data Resource and support the promotion of excellence in resource development and operation. It describes the specific indicators in more detail and explains their application within ELIXIR’s sustainability strategy and science policy actions, and in capacity building, life-cycle management and technical actions. The identification process is currently being implemented and tested for the first time. The findings and outcome will be evaluated by the ELIXIR Scientific Advisory Board in March 2017. Establishing the portfolio of ELIXIR Core Data Resources and ELIXIR Services is a key priority for ELIXIR and publicly marks the transition towards a cohesive infrastructure.

Impact of 18FDG-PET/CT on biological target volume (BTV) definition for treatment planning for non-small cell lung cancer patients

International Nuclear Information System (INIS)

Devic, Slobodan; Tomic, Nada; Faria, Sergio; Dean, Geoffrey; Lisbona, Robert; Parker, William; Kaufman, Chris; Podgorsak, Ervin B.

2007-01-01

This work represents our effort to test feasibility of FDG-based PET/CT on target volume delineation in radiotherapy treatment planning of NSCLC patients. Different methods have been developed to enable more precise target outlining using PET: Qualitative Visual Method, CTV=2.5 SUV units, linear SUV threshold function method, and CTV=40% Iso of Maximum Uptake Value. We are proposing reconstruction of three biological target volumes: necrotic BTV (same as PTV created by radiation oncologist using CT data), proliferating BTV (based on PET signal to background ratio 1:3) and hypoxic BTV (based on PET signal to background ratio of 1:19). Two IMRT plans were created and compared to the conventional treatment plan: 'conservative' IMRT plan delivers 52.5 Gy to the necrotic BTV and 65 Gy to the hypoxic BTV; 'radical' IMRT plan delivers 30 Gy to necrotic BTV, 52.5 Gy to proliferating BTV and 65 Gy to hypoxic BTV. Use of BTVs in IMRT plans is attractive because it increases dose to targets considered to need higher doses. It reduces considerably dose to heart and spinal cord, organs considered to limit dose escalation approaches in NSCLC treatment. 'Conservative' IMRT approach can be understood as a PET/CT-based concomitant boost to the tumor expressing the highest FDG uptake. 'Radical' plan implies deviation from the traditional uniform dose target coverage approach, with the intention of achieving better surrounding tissue sparing and ultimately allowing for dose escalation protocols relying on biologically based treatment planning

Draft genome of the medaka fish: a comprehensive resource for medaka developmental genetics and vertebrate evolutionary biology.

Science.gov (United States)

Takeda, Hiroyuki

2008-06-01

The medaka Oryzias latipes is a small egg-laying freshwater teleost, and has become an excellent model system for developmental genetics and evolutionary biology. The medaka genome is relatively small in size, approximately 800 Mb, and the genome sequencing project was recently completed by Japanese research groups, providing a high-quality draft genome sequence of the inbred Hd-rR strain of medaka. In this review, I present an overview of the medaka genome project including genome resources, followed by specific findings obtained with the medaka draft genome. In particular, I focus on the analysis that was done by taking advantage of the medaka system, such as the sex chromosome differentiation and the regional history of medaka species using single nucleotide polymorphisms as genomic markers.

A Local Net Volume Equation for Iowa

Science.gov (United States)

Jerold T. Hahn

1976-01-01

As a part of the 1974 Forest Survey of Iowa, the Station''s Forst Resources Evaluatioin Research Staff developed a merchantable tree volume equation and tables of coefficients for Iowa. They were developed for both board-foot (International ?-inch rule) and cubic foot volumes, for several species and species groups of growing-stock trees. The equation and...

What history tells us XXIX. Transfers from plant biology

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences; Volume 37; Issue 6. What history tells us XXIX. Transfers from plant biology: From cross protection to RNA interference and DNA vaccination. Michel Morange. Series Volume 37 Issue 6 December 2012 pp 949-952 ...

The Exploitation of Evolving Resources

CERN Document Server

McGlade, Jacqueline; Law, Richard

1993-01-01

The impact of man on the biosphere is profound. Quite apart from our capacity to destroy natural ecosystems and to drive species to extinction, we mould the evolution of the survivors by the selection pressures we apply to them. This has implications for the continued health of our natural biological resources and for the way in which we seek to optimise yield from those resources. Of these biological resources, fish stocks are particularly important to mankind as a source of protein. On a global basis, fish stocks provide the major source of protein for human consumption from natural ecosystems, amounting to some seventy million tonnes in 1970. Although fisheries management has been extensively developed over the last century, it has not hitherto considered the evolutionary consequences of fishing activity. While this omission may not have been serious in the past, the ever increasing intensity of exploitation and the deteriorating health of fish stocks has generated an urgent need for a better understanding...

Shared Communications: Volume 2. In-Depth Systems Research

Energy Technology Data Exchange (ETDEWEB)

Truett, LF

2004-09-22

This report is the second of two documents that examine the literature for actual examples of organizations and agencies that share communications resources. While the primary emphasis is on rural, intelligent transportation system (ITS) communications involving transit, examples will not be limited to rural activities, nor to ITS implementation, nor even to transit. In addition, the term ''communication'' will be broadly applied to include all information resources. The first document of this series, ''Shared Communications: Volume I. A Summary and Literature Review'', defines the meaning of the term ''shared communication resources'' and provides many examples of agencies that share resources. This document, ''Shared Communications: Volume II. In-Depth Systems Research'', reviews attributes that contributed to successful applications of the sharing communication resources concept. A few examples of each type of communication sharing are provided. Based on the issues and best practice realworld examples, recommendations for potential usage and recommended approaches for field operational tests are provided.

CORAL REEF BIOLOGICAL CRITERIA: USING THE CLEAN ...

Science.gov (United States)

Coral reefs are declining at unprecedented rates worldwide due to multiple interactive stressors including climate change and land-based sources of pollution. The Clean Water Act (CWA) can be a powerful legal instrument for protecting water resources, including the biological inhabitants of coral reefs. The objective of the CWA is to restore and maintain the chemical, physical and biological integrity of water resources. Coral reef protection and restoration under the Clean Water Act begins with water quality standards - provisions of state or Federal law that consist of a designated use(s) for the waters of the United States and water quality criteria sufficient to protect the uses. Aquatic life use is the designated use that is measured by biological criteria (biocriteria). Biocriteria are expectations set by a jurisdiction for the quality and quantity of living aquatic resources in a defined waterbody. Biocriteria are an important addition to existing management tools for coral reef ecosystems. The Technical Support Document “Coral Reef Biological Criteria: Using the Clean Water Act to Protect a National Treasure” will provide a framework to aid States and Territories in their development, adoption, and implementation of coral reef biocriteria in their respective water quality standards. The Technical Support Document “Coral Reef Biological Criteria: Using the Clean Water Act to Protect a National Treasure” will provide a framework for coral re

Natural products as a resource for biologically active compounds

International Nuclear Information System (INIS)

Hanke, F.J.

1986-01-01

The goal of this study was to investigate various sources of biologically active natural products in an effort to identify the active pesticidal compounds involved. The study is divided into several parts. Chapter 1 contains a discussion of several new compounds from plant and animal sources. Chapter 2 introduces a new NMR technique. In section 2.1 a new technique for better utilizing the lanthanide relaxation agent Gd(fod) 3 is presented which allows the predictable removal of resonances without line broadening. Section 2.2 discusses a variation of this technique for use in an aqueous solvent by applying this technique towards identifying the binding sites of metals of biological interest. Section 2.3 presents an unambiguous 13 C NMR assignment of melibiose. Chapter 3 deals with work relating to the molting hormone of most arthropods, 20-hydroxyecdysone. Section 3.1 discusses the use of two-dimensional NMR (2D NMR) to assign the 1 H NMR spectrum of this biologically important compound. Section 3.2 presents a new application for Droplet countercurrent chromatography (DCCC). Chapter 4 presents a basic improvement to the commercial DCCC instrument that is currently being applied to future commercial instruments. Chapter 5 discusses a curious observation of the effects that two previously known compounds, nagilactone C and (-)-epicatechin, have on lettuce and rice and suggest a possible new role for the ubiquitous flavanol (-)-epicatechin in plants

A role for biological optimization within the current treatment planning paradigm

International Nuclear Information System (INIS)

Das, Shiva

2009-01-01

Purpose: Biological optimization using complication probability models in intensity modulated radiotherapy (IMRT) planning has tremendous potential for reducing radiation-induced toxicity. Nevertheless, biological optimization is almost never clinically utilized, probably because of clinician confidence in, and familiarity with, physical dose-volume constraints. The method proposed here incorporates biological optimization after dose-volume constrained optimization so as to improve the dose distribution without detrimentally affecting the important reductions achieved by dose-volume optimization (DVO). Methods: Following DVO, the clinician/planner first identifies ''fixed points'' on the target and organ-at-risk (OAR) dose-volume histograms. These points represent important DVO plan qualities that are not to be violated within a specified tolerance. Biological optimization then maximally reduces a biological metric (illustrated with equivalent uniform dose (EUD) in this work) while keeping the fixed dose-volume points within tolerance limits, as follows. Incremental fluence adjustments are computed and applied to incrementally reduce the OAR EUDs while approximately maintaining the fixed points. This process of incremental fluence adjustment is iterated until the fixed points exceed tolerance. At this juncture, remedial fluence adjustments are computed and iteratively applied to bring the fixed points back within tolerance, without increasing OAR EUDs. This process of EUD reduction followed by fixed-point correction is repeated until no further EUD reduction is possible. The method is demonstrated in the context of a prostate cancer case and olfactory neuroblastoma case. The efficacy of EUD reduction after DVO is evaluated by comparison to an optimizer with purely biological (EUD) OAR objectives. Results: For both cases, EUD reduction after DVO additionally reduced doses, especially high doses, to normal organs. For the prostate case, bladder/rectum EUDs were

MIPS Arabidopsis thaliana Database (MAtDB): an integrated biological knowledge resource for plant genomics

Science.gov (United States)

Schoof, Heiko; Ernst, Rebecca; Nazarov, Vladimir; Pfeifer, Lukas; Mewes, Hans-Werner; Mayer, Klaus F. X.

2004-01-01

Arabidopsis thaliana is the most widely studied model plant. Functional genomics is intensively underway in many laboratories worldwide. Beyond the basic annotation of the primary sequence data, the annotated genetic elements of Arabidopsis must be linked to diverse biological data and higher order information such as metabolic or regulatory pathways. The MIPS Arabidopsis thaliana database MAtDB aims to provide a comprehensive resource for Arabidopsis as a genome model that serves as a primary reference for research in plants and is suitable for transfer of knowledge to other plants, especially crops. The genome sequence as a common backbone serves as a scaffold for the integration of data, while, in a complementary effort, these data are enhanced through the application of state-of-the-art bioinformatics tools. This information is visualized on a genome-wide and a gene-by-gene basis with access both for web users and applications. This report updates the information given in a previous report and provides an outlook on further developments. The MAtDB web interface can be accessed at http://mips.gsf.de/proj/thal/db. PMID:14681437

Uranium market and resources

International Nuclear Information System (INIS)

Capus, G.; Arnold, Th.

2004-01-01

The controversy about the extend of the uranium resources worldwide is still important, this article sheds some light on this topic. Every 2 years IAEA and NEA (nuclear energy agency) edit an inventory of uranium resources as reported by contributing countries. It appears that about 4.6 millions tons of uranium are available at a recovery cost less than 130 dollars per kg of uranium and a total of 14 millions tons of uranium can be assessed when including all existing or supposed resources. In fact there is enough uranium to sustain a moderate growth of the park of nuclear reactors during next decades and it is highly likely that the volume of uranium resources can allow a more aggressive development of nuclear energy. It is recalled that a broad use of the validated breeder technology can stretch the durability of uranium resources by a factor 50. (A.C.)

Fishery Biology Database (AGDBS)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Basic biological data are the foundation on which all assessments of fisheries resources are built. These include parameters such as the size and age composition of...

[Research on resources chemistry of Chinese medicinal materials and resources recycling utilization ways and goals and tasks].

Science.gov (United States)

Duan, Jin-ao; Su, Shu-lan; Guo, Sheng; Jiang, Shu; Liu, Pei; Yan, Hui; Qian, Da-wei; Zhu, Hua-xu; Tang, Yu-ping; Wu, Qi-nan

2015-09-01

The objects of research on the resources chemistry of Chinese medicinal materials (RCCMM) are promotion of efficient production, rational utilization and improving quality of CMM and natural products. The development of TCM cause depends on the efficient utilization and sustainable development of CMM, hinges on the technologies and methods for using and discovering medicinal biological resources, stand or fall on the extension of industy chains, detailed utilizaion of resource chemical components by multi-way, multi-level. All of these may help to the recycling utilization and sound development of RCMM. In this article, five respects were discussed to the RCCMM researches and resources recycling utilization ways and goals and tasks. First, based on the principle of resource scarcity, discovering or replacing CMM resources, protecting the rare or endangered species or resources. Second, based on the multifunctionality of CMM, realizing the value-added and value compensation, and promoting the utilization efficiency through systermatic and detailed exploitation and utilization. Third, based on the resource conservation and environment-friendly, reducing raw material consumption, lowering cost, promoting recycling utilization and elevating utilization efficiency. Fourth, based on the stratege of turning harm into good, using the invasive alien biological resources by multi-ways and enriching the medicial resources. Fifth, based on the method of structure modification of chemical components, exploring and enhancing the utility value of resouces chemical substances. These data should provide references and attention for improving the utilization efficiency, promoting the development of recycling economy, and changing the mode of economic growth of agriculture and industry of CMM fundamentally.

Water resources data, Idaho, 2002; Volume 1. Great Basin and Snake River basin above King Hill

Science.gov (United States)

Brennan, T.S.; Lehmann, A.K.; Campbell, A.M.; O'Dell, I.; Beattie, S.E.

2003-01-01

Water resources data for the 2002 water year for Idaho consists of records of stage, discharge, and water quality of streams; stage, contents, and water quality of lakes and reservoirs; discharge of irrigation diversions; and water levels and water quality of groundwater. The two volumes of this report contain discharge records for 196 stream-gaging stations and 15 irrigation diversions; stage only records for 5 stream-gaging stations; stage only for 6 lakes and reservoirs; contents only for 13 lakes and reservoirs; water-quality for 78 stream-gaging stations and partial record sites, 3 lakes sites, and 383 groundwater wells; and water levels for 425 observation network wells and 900 special project wells. Additional water data were collected at various sites not involved in the systematic data collection program and are published as miscellaneous measurements. These data represent that part of the National Water Data System operated by the U.S. Geological Survey and cooperating State and Federal agencies in Idaho, adjacent States, and Canada.

Revised draft: Northeastern Regional geologic characterization report. Volume 3. Plates

International Nuclear Information System (INIS)

1984-11-01

Volume 7(3) contains the following maps: Index Map; Faults, Ground Acceleration, and In Situ Stress; Rock and Mineral Resources; Drainage Basins and Groundwater Discharge Zones; Groundwater Resources; and Crystalline Rock Bodies

Yucca Mountain Biological Resources Monitoring Program

International Nuclear Information System (INIS)

1992-01-01

The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a possible site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a repository. To ensure that site characterization activities (SCA) do not adversely affect the Yucca Mountain area, an environmental program has been implemented to monitor and mitigate potential impacts and to ensure that activities comply with applicable environmental regulations. This report describes the activities and accomplishments during fiscal year 1991 (FY91) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Activities Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

Intellectual property right in genetic resources

Directory of Open Access Journals (Sweden)

Milošević Mirjana

2017-01-01

Full Text Available Plant genetic resources for food and agriculture are necessary in food production and biodiversity conservation. These are the most important natural resources, in addition to air, water and soil. Unfortunately, during the evolution large number of plant genetic resources has been lost. The biggest negative impact on loss of plant genetic resources had been made by humans through the modernization of agriculture and the creation of varieties of high genetic uniformity. FAO and its operation through international mechanisms, such as the adoption of the Convention on Biological Diversity, the first legal act which regulates all levels of biodiversity: ecosystems, species and genetic resources, biotechnology, including the Cartagena Protocol on Biosafety (regulates the transfer of genetic material across the border, contributed to the conservation of plant genetic resources for food and agriculture. In addition to the Convention on Biological Diversity, FAO has been defined by the International Treaty on Plant Genetic Resources for Food and Agriculture in more specific and detailed way, the preservation of genetic resources. The objectives of the International Treaty on Plant Genetic Resources for Food and Agriculture are the conservation and sustainable use of all plant genetic resources for food and agriculture and the fair and equitable sharing of the benefits arising out of their use. There are four basic pillars which form the substance of the Contract, Sustainable use of plant genetic resources, Farmers' Rights, the Multilateral System and the Global Information System. Two organizations, the International Biodiversity and the International Union for the Protection of New Varieties of Plants trying to solve the issues of protection of the population and old varieties as intellectual property.

Natural crayfish clone as emerging model for various biological ...

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences; Volume 36; Issue 2. Marmorkrebs: Natural crayfish clone as emerging model for various biological disciplines. Günter Vogt. Mini-review Volume 36 Issue 2 June 2011 pp 377-382. Fulltext. Click here to view fulltext PDF. Permanent link:

Nutritional Systems Biology

DEFF Research Database (Denmark)

Jensen, Kasper

and network biology has the potential to increase our understanding of how small molecules affect metabolic pathways and homeostasis, how this perturbation changes at the disease state, and to what extent individual genotypes contribute to this. A fruitful strategy in approaching and exploring the field...... biology research. The paper also shows as a proof-of-concept that a systems biology approach to diet is meaningful and demonstrates some basic principles on how to work with diet systematic. The second chapter of this thesis we developed the resource NutriChem v1.0. A foodchemical database linking...... sites of diet on the disease pathway. We propose a framework for interrogating the critical targets in colon cancer process and identifying plant-based dietary interventions as important modifiers using a systems chemical biology approach. The fifth chapter of the thesis is on discovering of novel anti...

Evaluation of a commercial biologically based IMRT treatment planning system

International Nuclear Information System (INIS)

Semenenko, Vladimir A.; Reitz, Bodo; Day, Ellen; Qi, X. Sharon; Miften, Moyed; Li, X. Allen

2008-01-01

A new inverse treatment planning system (TPS) for external beam radiation therapy with high energy photons is commercially available that utilizes both dose-volume-based cost functions and a selection of cost functions which are based on biological models. The purpose of this work is to evaluate quality of intensity-modulated radiation therapy (IMRT) plans resulting from the use of biological cost functions in comparison to plans designed using a traditional TPS employing dose-volume-based optimization. Treatment planning was performed independently at two institutions. For six cancer patients, including head and neck (one case from each institution), prostate, brain, liver, and rectal cases, segmental multileaf collimator IMRT plans were designed using biological cost functions and compared with clinically used dose-based plans for the same patients. Dose-volume histograms and dosimetric indices, such as minimum, maximum, and mean dose, were extracted and compared between the two types of treatment plans. Comparisons of the generalized equivalent uniform dose (EUD), a previously proposed plan quality index (fEUD), target conformity and heterogeneity indices, and the number of segments and monitor units were also performed. The most prominent feature of the biologically based plans was better sparing of organs at risk (OARs). When all plans from both institutions were combined, the biologically based plans resulted in smaller EUD values for 26 out of 33 OARs by an average of 5.6 Gy (range 0.24 to 15 Gy). Owing to more efficient beam segmentation and leaf sequencing tools implemented in the biologically based TPS compared to the dose-based TPS, an estimated treatment delivery time was shorter in most (five out of six) cases with some plans showing up to 50% reduction. The biologically based plans were generally characterized by a smaller conformity index, but greater heterogeneity index compared to the dose-based plans. Overall, compared to plans based on dose-volume

Timber resource of Wisconsin's Northwest Survey Unit, 1983.

Science.gov (United States)

W. Brad Smith

1984-01-01

The fourth inventory of the timber resource of the Northwest Wisconsin Survey Unit shows a 1.8% decline in commercial forest area and a 36% gain in growing-stock volume between 1968 and 1983. Presented are highlights and statistics on area, volume, growth, mortality, removals, utilization, and biomass.

Timber resource statistics for eastern Washington, 1995.

Science.gov (United States)

Neil McKay; Patricia M. Bassett; Colin D. MacLean

1995-01-01

This report summarizes a 1990-91 timber resource inventory of Washington east of the crest of the Cascade Range. The inventory was conducted on all private and public lands except National Forests. Timber resource statistics from National Forest inventories also are presented. Detailed tables provide estimates of forest area, timber volume, growth, mortality, and...

Advances in water resources management

CERN Document Server

Yang, Chih; Wang, Mu-Hao

2016-01-01

This volume provides in-depth coverage of such topics as multi-reservoir system operation theory and practice, management of aquifer systems connected to streams using semi-analytical models, one-dimensional model of water quality and aquatic ecosystem-ecotoxicology in river systems, environmental and health impacts of hydraulic fracturing and shale gas, bioaugmentation for water resources protection, wastewater renovation by flotation for water pollution control, determination of receiving water’s reaeration coefficient in the presence of salinity for water quality management, sensitivity analysis for stream water quality management, river ice process, and computer-aided mathematical modeling of water properties. This critical volume will serve as a valuable reference work for advanced undergraduate and graduate students, designers of water resources systems, and scientists and researchers. The goals of the Handbook of Environmental Engineering series are: (1) to cover entire environmental fields, includin...

Microfluidic devices for biological applications

CSIR Research Space (South Africa)

Potgieter, S

2010-01-01

Full Text Available Microfluidics is a multi-disciplinary field that deals with the behaviour, control and manipulation of fluids constrained to sub-millilitre volumes. It is proving to be a useful tool for biological studies, affording advantages such as reduced cost...

Molecular biology of Homo sapiens: Abstracts of papers presented at the 51st Cold Spring Harbor symposium on quantitative biology

International Nuclear Information System (INIS)

Watson, J.D.; Siniscalco, M.

1986-01-01

This volume contains abstracts of papers presented at the 51st Cold Springs Harbor Symposium on Quantitative Biology. The topic for this meeting was the ''Molecular Biology of Homo sapiens.'' Sessions were entitled Human Gene Map, Human Cancer Genes, Genetic Diagnosis, Human Evolution, Drugs Made Off Human Genes, Receptors, and Gene Therapy. (DT)

Northeastern Regional geologic characterization report. Volume 3. Plates. Final report

International Nuclear Information System (INIS)

1985-08-01

Volume 7(3) contains the following maps: index map; faults, ground acceleration, and in situ stress; rock and mineral resources; drainage basins and ground water discharge zones; ground water resources; and crystalline rock bodies

Standard biological parts knowledgebase.

Directory of Open Access Journals (Sweden)

Michal Galdzicki

2011-02-01

Full Text Available We have created the Knowledgebase of Standard Biological Parts (SBPkb as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org. The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org. SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL, a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate "promoter" parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible.

Standard Biological Parts Knowledgebase

Science.gov (United States)

Galdzicki, Michal; Rodriguez, Cesar; Chandran, Deepak; Sauro, Herbert M.; Gennari, John H.

2011-01-01

We have created the Knowledgebase of Standard Biological Parts (SBPkb) as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org). The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org). SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL), a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate “promoter” parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible. PMID:21390321

Standard biological parts knowledgebase.

Science.gov (United States)

Galdzicki, Michal; Rodriguez, Cesar; Chandran, Deepak; Sauro, Herbert M; Gennari, John H

2011-02-24

We have created the Knowledgebase of Standard Biological Parts (SBPkb) as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org). The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org). SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL), a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate "promoter" parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible.

Draft 1992 Resource Program : Technical Report.

Energy Technology Data Exchange (ETDEWEB)

United States. Bonneville Power Administration.

1992-01-01

The 1992 Resource Program will propose actions to meet future loads placed on the Bonneville Power Administration (BPA). It will also discuss and attempt to resolve resource-related policy issues. The Resource Program assesses resource availability and costs, and analyzes resource requirements and alternative ways of meeting those requirements through both conservation and generation resources. These general resource conclusions are then translated to actions for both conservation and generation. The Resource Program recommends budgets for the Office of Energy Resources for Fiscal Years (FY) 1994 and 1995. BPA's Resource Program bears directly on an important BPA responsibility: the obligation under the Northwest Power Act{sup 3} to meet the power requirements of public and private utility and direct service industrial (DSI) customers according to their contractual agreements. BPA's Draft 1992 Resource Program is contained in four documents: (1) 1992 Resource Program Summary; (2) Technical Report; (3) Technical Assumptions Appendix; and, (4) Conservation Implementation Plan. This volume is the Draft 1992 Resource Program Technical Report, a comprehensive document that provides supporting data and analyses for Resource Program recommendations.

Draft 1992 Resource Program : Technical Report.

Energy Technology Data Exchange (ETDEWEB)

United States. Bonneville Power Administration.

1992-01-01

The 1992 Resource Program will propose actions to meet future loads placed on the Bonneville Power Administration (BPA). It will also discuss and attempt to resolve resource-related policy issues. The Resource Program assesses resource availability and costs, and analyzes resource requirements and alternative ways of meeting those requirements through both conservation and generation resources. These general resource conclusions are then translated to actions for both conservation and generation. The Resource Program recommends budgets for the Office of Energy Resources for Fiscal Years (FY) 1994 and 1995. BPA`s Resource Program bears directly on an important BPA responsibility: the obligation under the Northwest Power Act{sup 3} to meet the power requirements of public and private utility and direct service industrial (DSI) customers according to their contractual agreements. BPA`s Draft 1992 Resource Program is contained in four documents: (1) 1992 Resource Program Summary; (2) Technical Report; (3) Technical Assumptions Appendix; and, (4) Conservation Implementation Plan. This volume is the Draft 1992 Resource Program Technical Report, a comprehensive document that provides supporting data and analyses for Resource Program recommendations.

A genome-wide gene function prediction resource for Drosophila melanogaster.

Directory of Open Access Journals (Sweden)

Han Yan

2010-08-01

Full Text Available Predicting gene functions by integrating large-scale biological data remains a challenge for systems biology. Here we present a resource for Drosophila melanogaster gene function predictions. We trained function-specific classifiers to optimize the influence of different biological datasets for each functional category. Our model predicted GO terms and KEGG pathway memberships for Drosophila melanogaster genes with high accuracy, as affirmed by cross-validation, supporting literature evidence, and large-scale RNAi screens. The resulting resource of prioritized associations between Drosophila genes and their potential functions offers a guide for experimental investigations.

Yucca Mountain biological resources monitoring program

International Nuclear Information System (INIS)

1993-02-01

The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a potential site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities (SCA) do not adversely affect the environment at Yucca Mountain, an environmental program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG ampersand G Energy Measurements, Inc. (EG ampersand G/EM) during fiscal year 1992 (FY92) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

Capital Flight and Transfer from Resource-Rich Developing Countries

OpenAIRE

Demachi, Kazue

2013-01-01

This paper analyzes the influence of international resource price movements on capital outflows from resource-rich developing countries (RRDCs) by distinguishing capital flight and capital transfers. The volume of capital flight and transfers are calculated and their determinants are analyzed using macro-panel data constituting 21 resource-rich developing countries from 1990 to 2011. Through the regression analysis, the linkage between capital flight and resource revenue as well as that betwe...

Iowa's forest resources in 2003

Science.gov (United States)

Earl C. Leatherberry; Gary J. Brand; Steve Pennington

2005-01-01

Reports the initial results of all five annual panels (1999-2003) of the fourth inventory of Iowa`s forest resources, the first annual inventory of the State. Includes information on forest area; volume; biomass; growth, mortality, and removals; and health.

Probes & Drugs portal: an interactive, open data resource for chemical biology

Czech Academy of Sciences Publication Activity Database

Škuta, Ctibor; Popr, M.; Muller, Tomáš; Jindřich, Jindřich; Kahle, Michal; Sedlák, David; Svozil, Daniel; Bartůněk, Petr

2017-01-01

Roč. 14, č. 8 (2017), s. 758-759 ISSN 1548-7091 R&D Projects: GA MŠk LO1220 Institutional support: RVO:68378050 Keywords : bioactive compound, ,, * chemical probe * chemical biology * portal Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8) Impact factor: 25.062, year: 2016

Common variants at 6q22 and 17q21 are associated with intracranial volume

NARCIS (Netherlands)

M.A. Ikram (Arfan); M. Fornage (Myriam); G.D. Smith; S. Seshadri (Sudha); R. Schmidt (Reinhold); S. Debette (Stéphanie); H.A. Vrooman (Henri); S. Sigurdsson (Stefan); S. Ropele (Stefan); H.R. Taal (Rob); D.O. Mook-Kanamori (Dennis); L.H. Coker (Laura); W.T. Longstreth Jr; W.J. Niessen (Wiro); A.L. DeStefano (Anita); A. Beiser (Alexa); A.P. Zijdenbos; M.V. Struchalin (Maksim); C.R. Jack Jr. (Clifford); F. Rivadeneira Ramirez (Fernando); A.G. Uitterlinden (André); D.S. Knopman (David); A.L. Hartikainen; C.E. Pennell (Craig); E. Thiering (Eelisabeth); E.A.P. Steegers (Eric); H. Hakonarson (Hakon); J. Heinrich (Joachim); C. Palmer (Cameron); M.-R. Jarvelin (Marjo-Riitta); M.I. McCarthy (Mark); S.F.A. Grant (Struan); B.S. Pourcain (Beate); N.J. Timpson (Nicholas); G.D. Smith; U. Sovio (Ulla); M.A. Nalls (Michael); R. Au (Rhoda); A. Hofman (Albert); H. Gudnason (Haukur); A. van der Lugt (Aad); T.B. Harris (Tamara); W.M. Meeks (William); M.W. Vernooij (Meike); M.A. van Buchem (Mark); D.J. Catellier (Diane); V.W.V. Jaddoe (Vincent); V. Gudnason (Vilmundur); B.G. Windham (B Gwen); P.A. Wolf (Philip); C.M. van Duijn (Cornelia); T.H. Mosley (Thomas); R. Schmidt (Reinhold); L.J. Launer (Lenore); M.M.B. Breteler (Monique); C. DeCarli (Charles); L.S. Adair (Linda); W.Q. Ang (Wei); M. Atalay (Mustafa); C.E.M. van Beijsterveldt (Toos); N.E. Bergen (Nienke); P.J. Benke (Paul); D. Berry (Diane); L. Coin (Lachlan); O.S.P. Davis (Oliver S.); P. Elliott (Paul); C. Flexeder (Claudia); T.M. Frayling (Timothy); R. Gaillard (Romy); M. Groen-Blokhuis (Maria); L.-K. Goh; C.M.A. Haworth (Claire M.); D. Hadley (David); J. Hedebrand (Johannes); A. Hinney (Anke); J.N. Hirschhorn (Joel); J.W. Holloway (John); J.J. Holst; J.J. Hottenga (Jouke Jan); M. Horikoshi (Momoko); V. Huikari (Ville); E. Hypponen (Elina); T.O. Kilpeläinen (Tuomas); M. Kirin (Mirna); M. Kowgier (Matthew); T.A. Lakka (Timo); L.A. Lange (Leslie); D.A. Lawlor (Debbie); T. Lehtimäki (Terho); A. Lewin (Alex); C.M. Lindgren (Cecilia); V. Lindi (Virpi); R. Maggi (Reedik); J.A. Marsh (Julie); C.M. Middeldorp (Christel); I.Y. Millwood (Iona); J.C. Murray (Jeffrey); M. Nivard (Michel); C. Nohr (Christian); I. Ntalla (Ioanna); E. Oken (Emily); K. Panoutsopoulou (Kalliope); J. Pararajasingham (Jennifer); A. Rodriguez (Alfredo Chapin); R.M. Salem (Rany); S. Sebert (Sylvain); N. Siitonen (Niina); D.P. Strachan (David); Y.Y. Teo (Yik Ying); B. Valcárcel (Beatriz); G.A.H.M. Willemsen (Gonneke); E. Zeggini (Eleftheria); D.I. Boomsma (Dorret); C. Cooper (Charles); M.H. Gillman (Matthew); B. Hocher (Berthold); T.A. Lakka (Timo); K.L. Mohlke (Karen); G.V. Dedoussis (George); K.K. Ong (Ken); E. Pearson (Ewan); T.S. Price (Thomas); C. Power (Christopher); O. Raitakari (Olli); S-M. Saw (Seang-Mei); A. Scherag (Andre); O. Simell (Olli); T.I.A. Sørensen (Thorkild); J.F. Wilson (James)

2012-01-01

textabstractDuring aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our

Advancing metabolic engineering through systems biology of industrial microorganisms

DEFF Research Database (Denmark)

Dai, Zongjie; Nielsen, Jens

2015-01-01

resources. The objective of systems biology is to gain a comprehensive and quantitative understanding of living cells and can hereby enhance our ability to characterize and predict cellular behavior. Systems biology of industrial microorganisms is therefore valuable for metabolic engineering. Here we review......Development of sustainable processes to produce bio-based compounds is necessary due to the severe environmental problems caused by the use of fossil resources. Metabolic engineering can facilitate the development of highly efficient cell factories to produce these compounds from renewable...... the application of systems biology tools for the identification of metabolic engineering targets which may lead to reduced development time for efficient cell factories. Finally, we present some perspectives of systems biology for advancing metabolic engineering further....

Animal-based medicines: biological prospection and the sustainable use of zootherapeutic resources

Directory of Open Access Journals (Sweden)

Eraldo M. Costa-Neto

2005-03-01

Full Text Available Animals have been used as medicinal resources for the treatment and relieve of a myriad of illnesses and diseases in practically every human culture. Although considered by many as superstition, the pertinence of traditional medicine based on animals cannot be denied since they have been methodically tested by pharmaceutical companies as sources of drugs to the modern medical science. The phenomenon of zootherapy represents a strong evidence of the medicinal use of animal resources. Indeed, drug companies and agribusiness firms have been evaluating animals for decades without paying anything to the countries from where these genetic resources are found. The use of animals' body parts as folk medicines is relevant because it implies additional pressure over critical wild populations. It is argued that many animal species have been overexploited as sources of medicines for the traditional trade. Additionally, animal populations have become depleted or endangered as a result of their use as experimental subjects or animal models. Research on zootherapy should be compatible with the welfare of the medicinal animals, and the use of their by-products should be done in a sustainable way. It is discussed that sustainability is now required as the guiding principle for biological conservation.Os animais são utilizados como recursos medicinais para o tratamento e alívio de um gama de doenças e enfermidades em praticamente toda cultura humana. A pertinência da medicina tradicional baseada em animais, embora considerada como superstição, não deve ser negada uma vez que os animais têm sido testados metodicamente pelas companhias farmacêuticas como fontes de drogas para a ciência médica moderna. O fenômeno da zooterapia representa uma forte evidência do uso medicinal de recursos animais. De fato, as indústrias farmacêuticas e de agronegócios há décadas vêm avaliando animais sem pagar tributos aos países detentores desses recursos gen

Biological Control in Brazil: an overview

OpenAIRE

Parra,José Roberto Postali

2014-01-01

The use of Biological Control methods is on the increase, mainly as a result of the mobilization of human resources in entomology studies since the establishment of graduate programs in this country in the 1960s. This review approaches the retrospective of Biological Control in Brazil in recent decades, with an emphasis on the "culture of applying agrochemicals" adopted by Brazilian growers, which constrains progress in this area. Successful cases of Biological Control have been reported on i...

Xylella fastidiosa comparative genomic database is an information resource to explore the annotation, genomic features, and biology of different strains

Directory of Open Access Journals (Sweden)

Alessandro M. Varani

2012-01-01

Full Text Available The Xylella fastidiosa comparative genomic database is a scientific resource with the aim to provide a user-friendly interface for accessing high-quality manually curated genomic annotation and comparative sequence analysis, as well as for identifying and mapping prophage-like elements, a marked feature of Xylella genomes. Here we describe a database and tools for exploring the biology of this important plant pathogen. The hallmarks of this database are the high quality genomic annotation, the functional and comparative genomic analysis and the identification and mapping of prophage-like elements. It is available from web site http://www.xylella.lncc.br.

Hawaii Energy Resource Overviews. Volume 4. Impact of geothermal resource development in Hawaii (including air and water quality)

Energy Technology Data Exchange (ETDEWEB)

Siegel, S.M.; Siegel, B.Z.

1980-06-01

The environmental consequences of natural processes in a volcanic-fumerolic region and of geothermal resource development are presented. These include acute ecological effects, toxic gas emissions during non-eruptive periods, the HGP-A geothermal well as a site-specific model, and the geothermal resources potential of Hawaii. (MHR)

Common variants at 6q22 and 17q21 are associated with intracranial volume

NARCIS (Netherlands)

Arfan Ikram, M.; Fornage, M.; Smith, A.V.; Seshadri, S.; Schmidt, R.; Debette, S.; Vrooman, H.A.; Sigurdsson, S.; Ropele, S.; Taal, H.R.; Mook-Kanamori, D.O.; Coker, L.H.; Longstreth, Jr. W.T.; Niessen, W.J.; DeStefano, A.L.; Beiser, A.; Zijdenbos, A.P.; Struchalin, M.; Jack, C.R.; Rivadeneira, F.; Uitterlinden, A.G.; Knopman, D.S.; Hartikainen, A.-L.; Pennell, C.E.; Thiering, E.; Steegers, E.A.P.; Hakonarson, H.; Heinrich, J.; Palmer, L.J.; Jarvelin, M.-R.; McCarthy, M.I.; Grant, S.F.A.; St Pourcain, B.; Timpson, N.J.; Smith, G.D.; Sovio, U.; van Beijsterveldt, C.E.M.; Groen-Blokhuis, M.M.; Hottenga, J.J.; Middeldorp, C.M.; Nivard, M.G.; Willemsen, G.; Boomsma, D.I.; Nalls, M.A.; Au, R.; Hofman, A.; Gudnason, H.; van der Lugt, A.; Harris, T.B.; Meeks, W.M.; Vernooij, M.W.; van Buchem, M.A.; Catellier, D.; Jaddoe, V.W.V.; Gudnason, V.; Windham, B.G.; Wolf, P.A.; van Duijn, C.M.; Mosley, T.H.; Schmidt, H.; Launer, L.J.; Breteler, M.M.B.; DeCarli, C.S.

2012-01-01

During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our genome-wide

Wind energy resource atlas. Volume 8. The southern Rocky Mountain region

Energy Technology Data Exchange (ETDEWEB)

Andersen, S.R.; Freeman, D.L.; Hadley, D.L.; Elliott, D.L.; Barchet, W.R.; George, R.L.

1981-03-01

The Southern Rocky Mountain atlas assimilates five collections of wind resource data: one for the region and one for each of the four states that compose the Southern Rocky Mountain region (Arizona, Colorado, New Mexico, and Utah). At the state level, features of the climate, topography and wind resource are discussed in greater detail than is provided in the regional discussion, and the data locations on which the assessment is based are mapped. Variations, over several time scales, in the wind resource at selected stations in each state are shown on graphs of monthly average and interannual wind speed and power, and hourly average wind speed for each season. Other graphs present speed, direction, and duration frequencies of the wind at these locations.

Timber resource statistics for southwest Washington.

Science.gov (United States)

Patricia M. Bassett; Daniel D. Oswald

1981-01-01

This report summarizes a 1978 timber-resource inventory of six counties in southwest Washington: Clark, Cowlitz, Lewis, Pacific, Skamania, and Wahkiakum. Detailed tables of forest area, timber volume, growth, mortality, and harvest are presented.

Molecular biology of Homo sapiens: Abstracts of papers presented at the 51st Cold Spring Harbor symposium on quantitative biology

Energy Technology Data Exchange (ETDEWEB)

Watson, J.D.; Siniscalco, M.

1986-01-01

This volume contains abstracts of papers presented at the 51st Cold Springs Harbor Symposium on Quantitative Biology. The topic for this meeting was the ''Molecular Biology of Homo sapiens.'' Sessions were entitled Human Gene Map, Human Cancer Genes, Genetic Diagnosis, Human Evolution, Drugs Made Off Human Genes, Receptors, and Gene Therapy. (DT)

Earth observation for regional scale environmental and natural resources management

Science.gov (United States)

Bernknopf, R.; Brookshire, D.; Faulkner, S.; Chivoiu, B.; Bridge, B.; Broadbent, C.

2013-12-01

Earth observations (EO) provide critical information to natural resource assessment. Three examples are presented: conserving potable groundwater in intense agricultural regions, maximizing ecosystem service benefits at regional scales from afforestation investment and management, and enabling integrated natural and behavioral sciences for resource management and policy analysis. In each of these cases EO of different resolutions are used in different ways to help in the classification, characterization, and availability of natural resources and ecosystem services. To inform decisions, each example includes a spatiotemporal economic model to optimize the net societal benefits of resource development and exploitation. 1) EO is used for monitoring land use in intensively cultivated agricultural regions. Archival imagery is coupled to a hydrogeological process model to evaluate the tradeoff between agrochemical use and retention of potable groundwater. EO is used to couple individual producers and regional resource managers using information from markets and natural systems to aid in the objective of maximizing agricultural production and maintaining groundwater quality. The contribution of EO is input to a nitrate loading and transport model to estimate the cumulative impact on groundwater at specified distances from specific sites (wells) for 35 Iowa counties and two aquifers. 2) Land use/land cover (LULC) derived from EO is used to compare biological carbon sequestration alternatives and their provisioning of ecosystem services. EO is used to target land attributes that are more or less desirable for enhancing ecosystem services in two parishes in Louisiana. Ecological production functions are coupled with value data to maximize the expected return on investment in carbon sequestration and other ancillary ecosystem services while minimizing the risk. 3) Environmental and natural resources management decisions employ probabilistic estimates of yet-to-find or yet

Atlas based brain volumetry: How to distinguish regional volume changes due to biological or physiological effects from inherent noise of the methodology.

Science.gov (United States)

Opfer, Roland; Suppa, Per; Kepp, Timo; Spies, Lothar; Schippling, Sven; Huppertz, Hans-Jürgen

2016-05-01

Fully-automated regional brain volumetry based on structural magnetic resonance imaging (MRI) plays an important role in quantitative neuroimaging. In clinical trials as well as in clinical routine multiple MRIs of individual patients at different time points need to be assessed longitudinally. Measures of inter- and intrascanner variability are crucial to understand the intrinsic variability of the method and to distinguish volume changes due to biological or physiological effects from inherent noise of the methodology. To measure regional brain volumes an atlas based volumetry (ABV) approach was deployed using a highly elastic registration framework and an anatomical atlas in a well-defined template space. We assessed inter- and intrascanner variability of the method in 51 cognitively normal subjects and 27 Alzheimer dementia (AD) patients from the Alzheimer's Disease Neuroimaging Initiative by studying volumetric results of repeated scans for 17 compartments and brain regions. Median percentage volume differences of scan-rescans from the same scanner ranged from 0.24% (whole brain parenchyma in healthy subjects) to 1.73% (occipital lobe white matter in AD), with generally higher differences in AD patients as compared to normal subjects (e.g., 1.01% vs. 0.78% for the hippocampus). Minimum percentage volume differences detectable with an error probability of 5% were in the one-digit percentage range for almost all structures investigated, with most of them being below 5%. Intrascanner variability was independent of magnetic field strength. The median interscanner variability was up to ten times higher than the intrascanner variability. Copyright © 2016 Elsevier Inc. All rights reserved.

Knee Fat Pad Volumes in Patients with Hemophilia and Their Relationship with Osteoarthritis

Directory of Open Access Journals (Sweden)

Annette von Drygalski

2017-01-01

Full Text Available Hemophilic arthropathy is a progressive, disabling condition with poorly understood pathobiology. Since there is an emerging interest to study the role of intra-articular fat pad size and biology in arthritic conditions, we explored fat pad volume changes in hemophilic arthropathy and to what extent they differed from osteoarthritis. We matched a cohort of 13 adult patients with hemophilic arthropathy of the knee with age- and gender-matched cohorts without osteoarthritis (“control cohort” and with the same degree of radiographic osteoarthritis (“OA cohort” in 1 : 2 fashion. Infrapatellar fat pad (IPFP and suprapatellar fat pad (SPFP volumes were calculated based on magnetic resonance imaging and differences in fat pad volumes, demographics, height, weight, and osteoarthritis scores were evaluated. Fat pad volumes were positively associated with body size parameters in all three cohorts but were unaffected by the degree of osteoarthritis. While IPFP volumes did not differ between cohorts, SPFP volumes expanded disproportionally with weight in hemophilia patients. Our observations indicate that IPFPs and SPFPs behave biologically differently in response to different arthritic stimuli. The exaggerated expansion of the SPFP in hemophilia patients highlights the importance of further studying the implications of fat pad biology for progression of hemophilic arthropathy.

Evaluation of the AGCU Expressmarker 16 and 22 PCR Amplification Kits Using Biological Samples Applied to FTA Micro Cards in Reduced Volume Direct PCR Amplification Reactions

Directory of Open Access Journals (Sweden)

Samantha J Ogden

2015-01-01

Full Text Available This study evaluated the performance of the  Wuxi AGCU ScienTech Incorporation (HuiShan, Wuxi, China AGCU Expressmarker 16 (EX 16 and 22 (EX22 short tandem repeat (STR amplification kits in reduced reaction volumes using direct polymerase chain reaction (PCR amplification workflows. The commercially available PowerPlex® 21 (PP21 System (Promega, Wisconsin, USA, which follows similar direct workflows, was used as a reference. Anticoagulate blood applied to chemically impregnated  FTA TM Micro Cards (GE Healthcare UK Limited, Amersham Place, Little Chalfont, Buckinghamshire, HP7 9NA, UK was used to represent a complex biological sample. Allelic concordance, first-pass success rate, average peak heights, heterozygous peak height ratios (HPHRs, and intracolor and intercolor peak height balance were determined. In reduced volume PCR reactions, the performances of both the EX16 and EX22 STR amplification kits were comparable to that of the PP21 System. The level of performance was maintained at PCR reaction volumes, which are 40% of that recommended. The EX22 and PP21 System kits possess comparable overlapping genome coverage. This study evaluated the performance of the AGCU EX16 and EX22 STR amplification kits in reduced PCR reaction volumes using direct workflows in combination with whole blood applied to FTA TM Micro Cards. Allelic concordance, first-pass success rate, average peak heights, HPHRs, and intracolor and intercolor peak height balance were determined. A concordance analysis was completed that compared the performance of the EX16 and EX22 kits using human blood applied to FTA Micro Cards in combination with full, half, and reduced PCR reaction volumes. The PP21 System (Promega was used as a reference kit. Where appropriate, the distributions of data were assessed using the Shapiro-Wilk test. For normally-distributed data, statistics were calculated using analysis of variance (ANOVA and for nonparametric data the Wilcoxon

Water resources data for Virginia, water year 1991. Volume 2. Ground-water-level and ground-water-quality records. Water-data report (Annual), 1 October 1991-30 September 1992

International Nuclear Information System (INIS)

Prugh, B.J.; Powell, E.D.

1993-01-01

Water-resources data for the 1992 water year for Virginia consist of records of water levels and water quality of ground-water wells. The report (Volume 2. Ground-Water-Level and Ground-Water-Quality Records) contains water levels at 356 observation wells and water quality at 2 wells. Locations of these wells are given in the report

CADDIS Volume 4. Data Analysis: Biological and Environmental Data Requirements

Science.gov (United States)

Overview of PECBO Module, using scripts to infer environmental conditions from biological observations, statistically estimating species-environment relationships, methods for inferring environmental conditions, statistical scripts in module.

Environmental resource document for the Idaho National Engineering Laboratory. Volume 1

Energy Technology Data Exchange (ETDEWEB)

Irving, J.S.

1993-07-01

This document contains information related to the environmental characterization of the Idaho National Engineering Laboratory (INEL). The INEL is a major US Department of Energy facility in southeastern Idaho dedicated to nuclear research, waste management, environmental restoration, and other activities related to the development of technology. Environmental information covered in this document includes land, air, water, and ecological resources; socioeconomic characteristics and land use; and cultural, aesthetic, and scenic resources.

Environmental resource document for the Idaho National Engineering Laboratory. Volume 2

Energy Technology Data Exchange (ETDEWEB)

Irving, J.S.

1993-07-01

This document contains information related to the environmental characterization of the Idaho National Engineering Laboratory (INEL). The INEL is a major US Department of Energy facility in southeastern Idaho dedicated to nuclear research, waste management, environmental restoration, and other activities related to the development of technology. Environmental information covered in this document includes land, air, water, and ecological resources; socioeconomic characteristics and land use; and cultural, aesthetic, and scenic resources.

Timber resource statistics for eastern Washington.

Science.gov (United States)

Patricia M. Bassett; Daniel D. Oswald

1983-01-01

This report summarizes a 1980 timber resource inventory of the 16 forested counties in Washington east of the crest of the Cascade Range. Detailed tables of forest area, timber volume, growth, mortality, and harvest are presented.

Advancing metabolic engineering through systems biology of industrial microorganisms.

Science.gov (United States)

Dai, Zongjie; Nielsen, Jens

2015-12-01

Development of sustainable processes to produce bio-based compounds is necessary due to the severe environmental problems caused by the use of fossil resources. Metabolic engineering can facilitate the development of highly efficient cell factories to produce these compounds from renewable resources. The objective of systems biology is to gain a comprehensive and quantitative understanding of living cells and can hereby enhance our ability to characterize and predict cellular behavior. Systems biology of industrial microorganisms is therefore valuable for metabolic engineering. Here we review the application of systems biology tools for the identification of metabolic engineering targets which may lead to reduced development time for efficient cell factories. Finally, we present some perspectives of systems biology for advancing metabolic engineering further. Copyright © 2015 Elsevier Ltd. All rights reserved.

NATO Advanced Research Workshop on Fluorescence and other Optical Properties of Biological Particles for Biological Warfare Agent Sensors

CERN Document Server

Hoekstra, Alfons; Videen, Gorden; Optics of Biological Particles

2007-01-01

This book covers the optics of single biological particles, both theory and experiment, with emphasis on Elastic Light Scattering and Fluorescence. It deals with the optics of bacteria (bio-aerosols), marine particles (selected phytoplankton communities) and red and white blood cells. Moreover, there are dedicated chapters on a general theory for scattering by a cell, and modelling and simulation of scattering by inhomogeneous biological cells. Finally, one chapter is dedicated to astro-biological signatures, discussing the possibilities for detecting non-terrestrial biological material. The volume has up-to-date discussions on new experimental and numerical techniques, and many examples of applications of these techniques in real-life systems, as used to detect and characterize e.g. biological warfare agents or human blood cells.

Timber resource of Michigan's Southern Lower Peninsula Unit, 1980.

Science.gov (United States)

Jerold T. Hahn

1982-01-01

The fourth inventory of the timber resource of Michigan's Southern Lower Peninsula Survey Unit shows a 12% decline in commercial forest area and a 26% gain in growing-stock volume between 1966 and 1980. Presented are highlights and statistics on area, volume, growth, mortality, removals, utilization, and biomass.

Genetics and molecular biology of breast cancer

Energy Technology Data Exchange (ETDEWEB)

King, M.C. [California Univ., Berkeley, CA (United States); Lippman, M. [Georgetown Univ. Medical Center, Washington, DC (United States)] [comps.

1992-12-31

This volume contains the abstracts of oral presentations and poster sessions presented at the Cold Springs Harbor Meeting on Cancer Cells, this meeting entitled Genetics and Molecular Biology of Breast Cancer.

National hydroelectric power resources study. Preliminary inventory of hydropower resources. Volume 3. Mid-Continent region

Energy Technology Data Exchange (ETDEWEB)

None

1979-07-01

The US Corps of Engineers' assessment of the nation's hydroelectric resources provides a current and comprehensive estimate of the potential for incremental or new generation at existing dams and other water resource projects, as well as for undeveloped sites in the US. The demand for hydroelectric power is addressed and various related policy and technical considerations are investigated to determine the incentives, constraints, and impacts of developing hydropower to meet a portion of the future energy demands. The comprehensive data represent the effort of the Corps of Engineers based on site-specific analysis and evaluation. Summary tables include estimates of the potential capacity and energy at each site in the inventory. The number of sites and potential capacity in each state are identified, but specific detailed information is included for sites in Colorado, Kansas, Montana, Nebraska, New Mexico, North Dakota, Oklahoma, South Dakota, Texas, and Wyoming.

Conservation landmarks: bureau of biological survey and national biological service

Science.gov (United States)

Friend, M.

1995-01-01

A century separates the recent development of the National Biological Service (NBS) and an early predecessor, the Bureau of Biological Survey (BBS). Both organizations were established at critical crossroads for the conservation of the nation's living biological resources and are conservation landmarks of their times. The BBS of the 192()'s was described as 'a government Bureau of the first rank, handling affairs of great scientific, educational, social, and above all, economic importance throughout the United States and its outlying possessions'' (Cameron 1929:144-145). This stature was achieved at a time of great social, economic, and ecological change. BBS had the vision to pioneer new approaches that led to enhanced understanding of the relation between people, other living things, and the environment. The NBS faces similar challenges to address the issues of the 1990's and beyond.

Protein Structure Initiative Material Repository: an open shared public resource of structural genomics plasmids for the biological community

Science.gov (United States)

Cormier, Catherine Y.; Mohr, Stephanie E.; Zuo, Dongmei; Hu, Yanhui; Rolfs, Andreas; Kramer, Jason; Taycher, Elena; Kelley, Fontina; Fiacco, Michael; Turnbull, Greggory; LaBaer, Joshua

2010-01-01

The Protein Structure Initiative Material Repository (PSI-MR; http://psimr.asu.edu) provides centralized storage and distribution for the protein expression plasmids created by PSI researchers. These plasmids are a resource that allows the research community to dissect the biological function of proteins whose structures have been identified by the PSI. The plasmid annotation, which includes the full length sequence, vector information and associated publications, is stored in a freely available, searchable database called DNASU (http://dnasu.asu.edu). Each PSI plasmid is also linked to a variety of additional resources, which facilitates cross-referencing of a particular plasmid to protein annotations and experimental data. Plasmid samples can be requested directly through the website. We have also developed a novel strategy to avoid the most common concern encountered when distributing plasmids namely, the complexity of material transfer agreement (MTA) processing and the resulting delays this causes. The Expedited Process MTA, in which we created a network of institutions that agree to the terms of transfer in advance of a material request, eliminates these delays. Our hope is that by creating a repository of expression-ready plasmids and expediting the process for receiving these plasmids, we will help accelerate the accessibility and pace of scientific discovery. PMID:19906724

Proceedings of the Scientific Meeting on Application of Isotopes and Radiation, Book I, Agricultural, Animal and Biology; Risalah Pertemuan Ilmiah Penelitian Dan Pengembangan Aplikasi Isotop Dan Radiasi. Buku 1, Pertanian, Peternakan dan Biologi

Energy Technology Data Exchange (ETDEWEB)

Suhadi, F; Sisworo, E L; Maha, M; Ismachin, M; Hilmy, N; Sumatra, M; Mugiono,; Wandowo,; Soebianto, Y S [Center for Application of Isotopes and Radiation, National Atomic Energy Agency, Serpong (Indonesia)

1998-07-01

The aim of the 10{sup t}h Meeting of the Isotope and Radiation Application is to disseminate the result of research on application of nuclear techniques on agriculture, animal, biology, chemistry, environment, radiation process and industry. The meeting was held in Jakarta, 18-19 February 1998, and there were 6 invited papers and 52 papers indexed individually. This proceeding is divided by two volumes. Volume I and volume II consists of agriculture, animal, biology and chemistry, environment, radiation process and industry, respectively.(ID)

Radiation, chemical and biological protection. Mass destruction weapons

International Nuclear Information System (INIS)

Janasek, D.; Svetlik, J.

2005-01-01

In this text-book mass destruction weapons and radiation, chemical and biological protection are reviewed. The text-book contains the following chapter: (1) Mass destruction weapons; (2) Matter and material; (3) Radioactive materials; (4) Toxic materials; (5) Biological resources; (6) Nuclear energetic equipment; Appendices; References.

Towards BioDBcore: a community-defined information specification for biological databases

Science.gov (United States)

Gaudet, Pascale; Bairoch, Amos; Field, Dawn; Sansone, Susanna-Assunta; Taylor, Chris; Attwood, Teresa K.; Bateman, Alex; Blake, Judith A.; Bult, Carol J.; Cherry, J. Michael; Chisholm, Rex L.; Cochrane, Guy; Cook, Charles E.; Eppig, Janan T.; Galperin, Michael Y.; Gentleman, Robert; Goble, Carole A.; Gojobori, Takashi; Hancock, John M.; Howe, Douglas G.; Imanishi, Tadashi; Kelso, Janet; Landsman, David; Lewis, Suzanna E.; Mizrachi, Ilene Karsch; Orchard, Sandra; Ouellette, B. F. Francis; Ranganathan, Shoba; Richardson, Lorna; Rocca-Serra, Philippe; Schofield, Paul N.; Smedley, Damian; Southan, Christopher; Tan, Tin Wee; Tatusova, Tatiana; Whetzel, Patricia L.; White, Owen; Yamasaki, Chisato

2011-01-01

The present article proposes the adoption of a community-defined, uniform, generic description of the core attributes of biological databases, BioDBCore. The goals of these attributes are to provide a general overview of the database landscape, to encourage consistency and interoperability between resources and to promote the use of semantic and syntactic standards. BioDBCore will make it easier for users to evaluate the scope and relevance of available resources. This new resource will increase the collective impact of the information present in biological databases. PMID:21097465

Electron Transfer in Chemistry and Biology – The Primary Events

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 12. Electron Transfer in Chemistry and Biology – The Primary Events in Photosynthesis. V Krishnan. General Article Volume 2 Issue 12 December 1997 pp 77-86. Fulltext. Click here to view fulltext PDF. Permanent link:

Biological Invasion and Loss of Endemic Biodiversity in the Thar ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 3. Nature Watch - Biological Invasion and Loss of Endemic Biodiversity in the Thar Desert. Ishwar Prakash. Feature Article Volume 6 Issue 3 March 2001 pp 76-85. Fulltext. Click here to view fulltext PDF. Permanent link:

Kansas' forest resources, 2005

Science.gov (United States)

W. Keith Moser; Gary J. Brand; Melissa Powers

2007-01-01

The USDA Forest Service, Northern Research Station, Forest Inventory and Analysis (NRS-FIA) program is changing to a Web-based, dynamically linked reporting system. As part of the process, this year NRS-FIA is producing this abbreviated summary of 2005 data. This resource bulletin reports on area, volume, and biomass using data from 2001 through 2005. Estimates from...

Regional Disparities in Online Map User Access Volume and Determining Factors

Science.gov (United States)

Li, R.; Yang, N.; Li, R.; Huang, W.; Wu, H.

2017-09-01

The regional disparities of online map user access volume (use `user access volume' in this paper to indicate briefly) is a topic of growing interest with the increment of popularity in public users, which helps to target the construction of geographic information services for different areas. At first place we statistically analysed the online map user access logs and quantified these regional access disparities on different scales. The results show that the volume of user access is decreasing from east to the west in China as a whole, while East China produces the most access volume; these cities are also the crucial economic and transport centres. Then Principal Component Regression (PCR) is applied to explore the regional disparities of user access volume. A determining model for Online Map access volume is proposed afterwards, which indicates that area scale is the primary determining factor for regional disparities, followed by public transport development level and public service development level. Other factors like user quality index and financial index have very limited influence on the user access volume. According to the study of regional disparities in user access volume, map providers can reasonably dispatch and allocate the data resources and service resources in each area and improve the operational efficiency of the Online Map server cluster.

Applications of dynamical systems in biology and medicine

CERN Document Server

Radunskaya, Ami

2015-01-01

This volume highlights problems from a range of biological and medical applications that can be interpreted as questions about system behavior or control.  Topics include drug resistance in cancer and malaria, biological fluid dynamics, auto-regulation in the kidney, anti-coagulation therapy, evolutionary diversification and photo-transduction.  Mathematical techniques used to describe and investigate these biological and medical problems include ordinary, partial and stochastic differentiation equations, hybrid discrete-continuous approaches, as well as 2 and 3D numerical simulation. .

Academy of Human Resource Development Conference Proceedings (Raleigh-Durham, North Carolina, March 8-12, 2000).

Science.gov (United States)

Kuchinke, K. Peter, Ed.

This two-volume document contains the proceedings of the 2000 conference of the Academy of Human Resource Development (AHRD). Volume 1 contains the following materials: conference overview; text of a town forum on social responsibility and human resource development (HRD); papers from symposia 1-24; and papers from innovative sessions 1-4. The…

Revised draft: North Central Regional geologic characterization report. Volume 2. Plates

International Nuclear Information System (INIS)

1984-11-01

Volume 8(2) comprises the following maps pertaining to the North-Central Region: Index Map; Overburden Thickness; Faults and Ground Acceleration; Rock and Mineral Resources; Groundwater Basins and Potential Major Zones; Groundwater Resource Potential; and a Geologic Map

Book review: Aquatic insect ecology: 1. Biology and habitat

OpenAIRE

Arnett, Ross H.

2010-01-01

Book Review: A comprehensive treatment of the ecology of aquatic insects in one place is needed for both students and researchers. Professor Ward is doing this in two volumes. The first volume covers the biology and habitats, as indicated in the subtitle, of the 13 insect orders that are either entirely aquatic at some stage, or those with some members aquatic at some stage. The second volume will be devoted entirely to the feeding ecology of these aquatic species.

National hydroelectric power resources study. Preliminary inventory of hydropower resources. Volume 6. Northeast region

Energy Technology Data Exchange (ETDEWEB)

None

1979-07-01

In the Northeast region, the physical potential for all sites exceeds 33,000 MW of capacity with an estimated average annual energy of some 153,000 GWH. By comparison, the available data represent about 6% of the total capacity and 11% of the hydroelectric energy potential estimated for the entire US. Of the total capacity estimated for the region, 6100 MW has been installed. The remainder (27,200 MW, excluding the undeveloped capacity in the New England States) is the maximum which could be developed by upgrading and expanding existing projects (18,700 MW), and by installing new hydroelectric power capacity at all potentially feasible, undeveloped sites (8500 MW). Small-scale facilities account for about 15% of the region's total installed capacity, but another 1800 MW could be added to these and other small water-resource projects. In addition, 500 MW could be installed at potentially feasible, undeveloped small-scale sites. The small-scale resource varies considerably, with the states of New York, Maine, and New Hampshire having the largest potential for incremental development at existing projects in the Northeast region. West Virginia, Maryland, Delaware, New Jersey, Pennsylvania, New York, Connecticut, Massachusetts, Rhode Island, New Hampshire, Vermont, and Maine comprise the Northeast region.

United States mineral resources

Science.gov (United States)

Brobst, Donald A.; Pratt, Walden P.

1973-01-01

The work on this volume began in January 1972, but in a broader sense its production began many years ago. The chapters were written by geologists most of whom have had many years of experience studying the geology of mineral deposits, and more particularly the commodities about which they have written here. A total of nearly 2,300 man-years of professional experience in the geology of mineral resources is represented by the authors of the volume, and about 30 man-years went directly into its preparation. Each chapter contains not only a synthesis of the state of knowledge of the geology of the commodity, but also an appraisal of the known resources, and an examination of the geologic possibilities for finding additional deposits. In January 1972, responsibility for the preparation of the volume was assigned to us as co-editors, and we were given a tentative list of commodities and authors. We provided each author with a suggested outline of general topics to be covered, and some guidelines as to scope and philosophy of approach, but beyond that we avoided any attempt to fit each chapter into a stereotype. Moreover, the types of commodities range from the major metals and industrial minerals such as copper, silver, and fluorspar, which have been the subject of geologic research for years, to other commodities that are of such varied geologic nature (such as pigments or gemstones) or of such minor present importance (such as scandium or thallium) that they cannot be treated from the same viewpoint as the major minerals. The chapters range, therefore, from comprehensive summary reports to general essays that reflect the individuality of the authors as well as the variation among commodities. Throughout the book the emphasis is on geology, but each chapter contains some summary information on uses, technology, and economics. These summaries are not meant to be exhaustive, however, and additional details are in the 1970 edition of "Mineral Facts and Problems" (Bulletin

Conflicts over natural resources in the Global South : conceptual approaches

NARCIS (Netherlands)

Bavinck, M.; Pellegrini, L.; Mostert, E.

2014-01-01

Inhabitants of poor, rural areas in the Global South heavily depend on natural resources in their immediate vicinity. Conflicts over and exploitation of these resources - whether it is water, fish, wood fuel, minerals, or land - severely affect their livelihoods. The contributors to this volume

Understanding Biological Regulation Through Synthetic Biology.

Science.gov (United States)

Bashor, Caleb J; Collins, James J

2018-03-16

Engineering synthetic gene regulatory circuits proceeds through iterative cycles of design, building, and testing. Initial circuit designs must rely on often-incomplete models of regulation established by fields of reductive inquiry-biochemistry and molecular and systems biology. As differences in designed and experimentally observed circuit behavior are inevitably encountered, investigated, and resolved, each turn of the engineering cycle can force a resynthesis in understanding of natural network function. Here, we outline research that uses the process of gene circuit engineering to advance biological discovery. Synthetic gene circuit engineering research has not only refined our understanding of cellular regulation but furnished biologists with a toolkit that can be directed at natural systems to exact precision manipulation of network structure. As we discuss, using circuit engineering to predictively reorganize, rewire, and reconstruct cellular regulation serves as the ultimate means of testing and understanding how cellular phenotype emerges from systems-level network function. Expected final online publication date for the Annual Review of Biophysics Volume 47 is May 20, 2018. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

1993 Pacific Northwest Loads and Resources Study, Technical Appendix: Volume 2, Book 1, Energy.

Energy Technology Data Exchange (ETDEWEB)

United States. Bonneville Power Administration.

1993-12-01

The 1993 Pacific Northwest Loads and Resources Study establishes the Bonneville Power Administration`s (BPA) planning basis for supplying electricity to BPA customers. The Loads and Resources Study is presented in three documents: (1) this technical appendix detailing loads and resources for each major Pacific and Northwest generating utility, (2) a summary of Federal system and Pacific Northwest region loads and resources, and (3) a technical appendix detailing forecasted Pacific Northwest economic trends and loads. This analysis updates the 1992 Pacific Northwest Loads and Resources Study Technical Appendix published in December 1992. This technical appendix provides utility-specific information that BPA uses in its long-range planning. It incorporates the following for each utility (1) Electrical demand firm loads; (2) Generating resources; and (3) Contracts both inside and outside the region. This document should be used in combination with the 1993 Pacific Northwest Loads and Resources Study, published in December 1993, because much of the information in that document is not duplicated here.

1991 Pacific Northwest Loads and Resources Study, Technical Appendix: Volume 1.

Energy Technology Data Exchange (ETDEWEB)

United States. Bonneville Power Administration.

1992-03-01

This publication provides detailed documentation of the load forecast scenarios and assumptions used in preparing BPA's 1991 Pacific Northwest Loads and Resources Study (the Study). This is one of two technical appendices to the Study; the other appendix details the utility-specific loads and resources used in the Study. The load forecasts and assumption were developed jointly by Bonneville Power Administration (BPA) and Northwest Power Planning Council (Council) staff. This forecast is also used in the Council's 1991 Northwest Conservation and Electric Power Plan (1991 Plan).

30 CFR 203.73 - How do suspension volumes apply to natural gas?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do suspension volumes apply to natural gas... suspension volumes apply to natural gas? You must measure natural gas production under the royalty-suspension volume as follows: 5.62 thousand cubic feet of natural gas, measured in accordance with 30 CFR part 250...

Optimal Resource Management in a Stochastic Schaefer Model

OpenAIRE

Richard Hartman

2008-01-01

This paper incorporates uncertainty into the growth function of the Schaefer model for the optimal management of a biological resource. There is a critical value for the biological stock, and it is optimal to do no harvesting if the biological stock is below that critical value and to exert whatever harvesting effort is necessary to prevent the stock from rising above that critical value. The introduction of uncertainty increases the critical value of the stock.

SEEK: a systems biology data and model management platform.

NARCIS (Netherlands)

Wolstencroft, K.J.; Owen, S.; Krebs, O.; Nguyen, Q.; Stanford, N.J.; Golebiewski, M.; Weidemann, A.; Bittkowski, M.; An, L.; Shockley, D.; Snoep, J.L.; Mueller, W.; Goble, C.

2015-01-01

Background: Systems biology research typically involves the integration and analysis of heterogeneous data types in order to model and predict biological processes. Researchers therefore require tools and resources to facilitate the sharing and integration of data, and for linking of data to systems

Volume of the crocodilian brain and endocast during ontogeny

Czech Academy of Sciences Publication Activity Database

Jirák, D.; Janáček, Jiří

2017-01-01

Roč. 12, č. 6 (2017), č. článku e0178491. E-ISSN 1932-6203 R&D Projects: GA ČR(CZ) GAP302/12/1207; GA ČR(CZ) GA13-12412S Institutional support: RVO:67985823 Keywords : brain volume * endoneurocranium * crocodilians * magnetic resonance imaging Subject RIV: EA - Cell Biology OBOR OECD: Developmental biology Impact factor: 2.806, year: 2016

Automated Resource Classifier for agglomerative functional ...

Indian Academy of Sciences (India)

2007-06-16

Jun 16, 2007 ... Automated resource; functional classification; integrative biology ... which is an open source software meeting the user requirements of flexibility. ... entries into any of the 7 basic non-overlapping functional classes: Cell wall, ...

Introduction to Northeast Pacific Shark Biology, Research, and Conservation, Part B.

Science.gov (United States)

Larson, Shawn E; Lowry, Dayv

Sharks are iconic, sometimes apex, predators found in every ocean. Because of their ecological role as predators and concern over the stability of their populations, there has been an increasing amount of work focused on shark conservation around the world in recent decades. The populations of sharks that reside in the Northeast Pacific (NEP) Ocean bordering the west coast of the United States reside in one of the most economically and ecologically important oceanic regions in the world. Volume 78 of Advances in Marine Biology (AMB) is a companion to Volume 77, which focused primarily on NEP shark biodiversity, organismal biology, and ecology. Volume 78 highlights fisheries and the conservation implications of fisheries management; shark population modelling and the conservation impacts of these models given that many life history metrics of NEP sharks necessary to accurately run these models are still unknown; the value of captive sharks to the biology, outreach, and conservation of NEP sharks; and the conservation value of citizen science and shark ecotourism. Together these volumes encapsulate the current state of the knowledge for sharks in the NEP and lay the foundation for protecting, managing, and learning from these species in the face evolving natural conditions and societal opinions. © 2017 Elsevier Ltd All rights reserved.

Impact of Climate Change on Water Resources in Taiwan

OpenAIRE

An-Yuan Tsai Wen-Cheng Huang

2011-01-01

This paper establishes a comprehensive assessment model to measure the regional impact of climate change on Taiwan¡¦s water resources. Working from future rainfall data simulated by Japan¡¦s high-resolution GCM model JMA/MRI TL959L60 in a SRES-A1B scenario, we first apply climate change to an assessment model of renewable water resources to estimate the volume of renewable water resources on a regional basis. We then conduct a water resources system simulation based on estimates of future wat...

Molecular image-guided radiation treatment planing using biological target volume (BTV)for advanced esophageal cancer

International Nuclear Information System (INIS)

Tamamura, Hiroyasu; Sasaki, Makoto; Bou, Sayuri; Satou, Yoshitaka; Minami, Hiroki; Saga, Yusuke; Aoyama, Masashi; Yamamoto, Kazutaka; Kawamura, Mariko

2016-01-01

As the biological mechanisms of cancer cell proliferation become clear at molecular level, 'precision therapy' is attracting a great attention, in which the irradiation dose and area are determined in consideration of these molecular mechanism. For this sophisticated radiotherapy, it is essential to evaluate the tumor morphology and proliferation/activation of cancer cells before radiation treatment planning. Generally, cancer cells start to proliferate when their activity levels increase, and subsequently primary tumor or metastatic tumor that can De recognized by CT scan or MRI start to develop. Thus, when proliferation of cancer cells occurs and tumor start to develop, a vast amount of energy is required for proliferation and cancer cells obtain a part of this energy from glucose in the body. Therefore, we can get the information on the status of metabolism and density of cancer cells by PET using F-18-FDG, which is structurally similar to glucose. It is a general belief that, when conducting evaluation using F18-FDG-PET, evaluation of proliferation of cancer cells before tumor formation might be possible at the cell level by evaluating and visualizing glucose metabolism in cancer cells that proliferate in a manner that they cannot be visualized morphologically by using CT scan or MRI. Therefore, when performing sophisticated precision radiotherapy, it is important to implement radiation treatment plan including information obtained from FDG-PET imaging. Many studies have reported usefulness of FDG-PET imaging for esophagus cancer so far, indicating the efficacy of using FDG-PET imaging for radiation treatment plan of esophagus cancer as well. However, few studies have described how to use FDG-PET imaging for radiation treatment plan for esophagus cancer. In this review, therefore, we will outline the usefulness of molecular image-guided radiation treatment plan, in which biological target volume (BTV) and the actual radiation treatment plan using FDG

Water resources data, Idaho, 2002; Volume 2. Upper Columbia River basin and Snake River basin below King Hill

Science.gov (United States)

Brennan, T.S.; Lehmann, A.K.; Campbell, A.M.; O'Dell, I.; Beattie, S.E.

2003-01-01

Water resources data for the 2002 water year for Idaho consists of records of stage, discharge, and water quality of streams; stage, contents, and water quality of lakes and reservoirs; discharge of irrigation diversions; and water levels and water quality of groundwater. The two volumes of this report contain discharge records for 196 stream-gaging stations and 15 irrigation diversions; stage only records for 5 stream-gaging stations; stage only for 6 lakes and reservoirs; contents only for 13 lakes and reservoirs; water-quality for 78 stream-gaging stations and partial record sites, 3 lakes sites, and 383 groundwater wells; and water levels for 425 observation network wells and 900 special project wells. Additional water data were collected at various sites not involved in the systematic data collection program and are published as miscellaneous measurements. These data represent that part of the National Water Data System operated by the U.S. Geological Survey and cooperating State and Federal agencies in Idaho, adjacent States, and Canada.

Infusing Outdoor Field Experiences into the Secondary Biology Curriculum.

Science.gov (United States)

Owens, Ginny

1984-01-01

To offer students biological field experiences, teachers should use their own basic skills, be enthusiastic motivators, participate in community programs/courses/workshops to acquire additional skills/knowledge for outdoor biological education, plan outdoor excursions with safety considerations in mind, and use available resources for classroom…

Node fingerprinting: an efficient heuristic for aligning biological networks.

Science.gov (United States)

Radu, Alex; Charleston, Michael

2014-10-01

With the continuing increase in availability of biological data and improvements to biological models, biological network analysis has become a promising area of research. An emerging technique for the analysis of biological networks is through network alignment. Network alignment has been used to calculate genetic distance, similarities between regulatory structures, and the effect of external forces on gene expression, and to depict conditional activity of expression modules in cancer. Network alignment is algorithmically complex, and therefore we must rely on heuristics, ideally as efficient and accurate as possible. The majority of current techniques for network alignment rely on precomputed information, such as with protein sequence alignment, or on tunable network alignment parameters, which may introduce an increased computational overhead. Our presented algorithm, which we call Node Fingerprinting (NF), is appropriate for performing global pairwise network alignment without precomputation or tuning, can be fully parallelized, and is able to quickly compute an accurate alignment between two biological networks. It has performed as well as or better than existing algorithms on biological and simulated data, and with fewer computational resources. The algorithmic validation performed demonstrates the low computational resource requirements of NF.

Atomic Force Microscopy - A Tool to Unveil the Mystery of Biological ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 15; Issue 7. Atomic Force Microscopy - A Tool to Unveil the Mystery of Biological Systems ... Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560 ...

Information Literacy in Biology Education: An Example from an Advanced Cell Biology Course

Science.gov (United States)

Porter, John R.

2005-01-01

Information literacy skills are critically important for the undergraduate biology student. The ability to find, understand, evaluate, and use information, whether from the scientific literature or from Web resources, is essential for a good understanding of a topic and for the conduct of research. A project in which students receive information…

Natural resources and control processes

CERN Document Server

Wang, Mu-Hao; Hung, Yung-Tse; Shammas, Nazih

2016-01-01

This edited book has been designed to serve as a natural resources engineering reference book as well as a supplemental textbook. This volume is part of the Handbook of Environmental Engineering series, an incredible collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. It complements two other books in the series including Environmental and Natural Resources Engineering and Integrated Natural Resources Management that serve as a basis for advanced study or specialized investigation of the theory and analysis of various natural resources systems. This book covers the management of many waste sources including those from agricultural livestock, deep-wells, industries manufacturing dyes, and municipal solid waste incinerators. The purpose of this book is to thoroughly prepare the reader for understanding the sources, treatment and control methods of toxic wastes shown to have harmful effects on the environment. Chapters provide information ...

Research on Evaluation of resource allocation efficiency of transportation system based on DEA

Science.gov (United States)

Zhang, Zhehui; Du, Linan

2017-06-01

In this paper, we select the time series data onto 1985-2015 years, construct the land (shoreline) resources, capital and labor as inputs. The index system of the output is freight volume and passenger volume, we use Quantitative analysis based on DEA method evaluated the resource allocation efficiency of railway, highway, water transport and civil aviation in China. Research shows that the resource allocation efficiency of various modes of transport has obvious difference, and the impact on scale efficiency is more significant. The most important two ways to optimize the allocation of resources to improve the efficiency of the combination of various modes of transport is promoting the co-ordination of various modes of transport and constructing integrated transportation system.

North Central Regional geologic characterization report. Volume 2. Plates. Final report

International Nuclear Information System (INIS)

1985-08-01

Volume 8(2) contains the following maps: Geologic map of the Lake Superior Region (Minnesota, Wisconsin, and northern Michigan); Index Map; Overburden Thickness; Faults and Ground Acceleration; Rock and Mineral Resources; Ground Water Basins and Potential Major Discharge Zones; and Ground Water Resource Potential

Biological Remediation of Petroleum Contaminants

Science.gov (United States)

Kuhad, Ramesh Chander; Gupta, Rishi

Large volumes of hazardous wastes are generated in the form of oily sludges and contaminated soils during crude oil transportation and processing. Although many physical, chemical and biological treatment technologies are available for petroleum contaminants petroleum contaminants in soil, biological methods have been considered the most cost-effective. Practical biological remediation methods typically involve direct use of the microbes naturally occurring in the contaminated environment and/or cultured indigenous or modified microorganisms. Environmental and nutritional factors, including the properties of the soil, the chemical structure of the hydrocarbon(s), oxygen, water, nutrient availability, pH, temperature, and contaminant bioavailability, can significantly affect the rate and the extent of hydrocarbon biodegradation hydrocarbon biodegradation by microorganisms in contaminated soils. This chapter concisely discusses the major aspects of bioremediation of petroleum contaminants.

Issues about Human Resources Recruitment

Directory of Open Access Journals (Sweden)

Aurel Manolescu

2008-04-01

Full Text Available As to ensure its success or even for surviving, organizations must settle accordingly some issues regarding the human resources enlistment, presented in great details within the article, whose success settlement ensure, concomitantly, the success of the entire assurance process with personnel, process extremely important, if there are taken into consideration, especially, the effects of some possible errors or hire errors. Therefore, the human resources recruitment tends to become a complex and expensive activity and, concomitantly, an independent activity, sustained both through the necessary work volume as well as through its importance for the organization.

Biology and Mechanics of Blood Flows Part I: Biology

CERN Document Server

Thiriet, Marc

2008-01-01

Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part I of this two-volume sequence, Biology, addresses the nanoscopic and microscopic scales. The nanoscale corresponds to the scale of biochemical reaction cascades involved in cell adaptation to mechanical stresses among other stimuli. The microscale is the scale of stress-induced tissue remodeling associated with acute or chronic loadings. The cardiovascular system, like any physiological system, has a complicated three-dimensional structure and composition. Its time dependent behavior is regulated, and this complex system has many components. In this authoritative work, the author provides a survey of relevant cell components and processes, with detailed coverage of the electrical and mechanical behaviors of vascular cells, tissues, and organs. Because the behaviors of vascular cells and tissues are tightly coupl...

Mathematical methods in biology and neurobiology

CERN Document Server

Jost, Jürgen

2014-01-01

Mathematical models can be used to meet many of the challenges and opportunities offered by modern biology. The description of biological phenomena requires a range of mathematical theories. This is the case particularly for the emerging field of systems biology. Mathematical Methods in Biology and Neurobiology introduces and develops these mathematical structures and methods in a systematic manner. It studies:   • discrete structures and graph theory • stochastic processes • dynamical systems and partial differential equations • optimization and the calculus of variations.   The biological applications range from molecular to evolutionary and ecological levels, for example:   • cellular reaction kinetics and gene regulation • biological pattern formation and chemotaxis • the biophysics and dynamics of neurons • the coding of information in neuronal systems • phylogenetic tree reconstruction • branching processes and population genetics • optimal resource allocation • sexual recombi...

ChemProt: a disease chemical biology database

DEFF Research Database (Denmark)

Taboureau, Olivier; Nielsen, Sonny Kim; Audouze, Karine Marie Laure

2011-01-01

Systems pharmacology is an emergent area that studies drug action across multiple scales of complexity, from molecular and cellular to tissue and organism levels. There is a critical need to develop network-based approaches to integrate the growing body of chemical biology knowledge with network...... biology. Here, we report ChemProt, a disease chemical biology database, which is based on a compilation of multiple chemical-protein annotation resources, as well as disease-associated protein-protein interactions (PPIs). We assembled more than 700 000 unique chemicals with biological annotation for 30...... evaluation of environmental chemicals, natural products and approved drugs, as well as the selection of new compounds based on their activity profile against most known biological targets, including those related to adverse drug events. Results from the disease chemical biology database associate citalopram...

ON PRICE CHOICE AT SELLING OF INFORMATION RESOURCES

Directory of Open Access Journals (Sweden)

O. S. Ivanova

2015-05-01

Full Text Available The paper considers the problem of the pricing policy determination in the company, selling information resource at the market. The problem of the optimal price determination for an information resource is solved depending on the time for the case when the seller-company has no competitors in the market, the market is saturated, and buyers are not able to further spread of the resource. Conditions for the optimal choice of information resource price have been obtained; the maximum possible income of the company has been calculated for linear demand function, and conditions, determining the duration and volume of sales, providing the maximum of average income of the company, have been obtained as well. The problem of optimal price choice is solved by macrosystem approach that has made it possible to reduce it to the isoperimetric kind. It is shown that the optimal price dependence on time for a linear demand function should provide a linearly increasing rate of sales. Conditions have been derived under which the sales proceedings for an information resource are positive, relationship is determined between volume of sales and timeline at which the average income during the sales reaches its maximum. The results are given in dimensionless form, thereby reducing the number of independent parameters. These results are usable for the pricing analysis of software and other information products.

2005 resource options report

International Nuclear Information System (INIS)

Morris, T.

2005-01-01

This resource options report (ROR) fulfils regulatory requirements in British Columbia's two-year resource planning process. It identifies a wide range of resources and technologies that could be used to meet BC Hydro's future electricity demand. As such, it facilitates a transparent public review of resource options which include both supply-side and demand-side options. The resource options that will be used in the 2005 integrated electricity plan (IEP) were characterized. This ROR also documents where there is a general agreement or disagreement on the resource type characterization, based on the First Nations and Stakeholder engagement. BC Hydro used current information to provide realistic ranges on volume and cost to characterize environmental and social attributes. The BC Hydro system was modelled to assess the benefit and cost of various resource options. The information resulting from this ROR and IEP will help in making decisions on how to structure competitive acquisition calls and to determine the level of transmission services needed to advance certain BC Hydro projects. The IEP forecasts the nature and quantity of domestic resources required over the next 20 years. A strategic direction on how those needs will be met has been created to guide the management of BC Hydro's energy resources. Supply-side options include near-commercial technologies such as energy storage, ocean waves, tidal, fuel cells and integrated coal gasification combined cycle technology. Supply-side options also include natural gas, coal, biomass, geothermal, wind, and hydro. 120 refs., 39 tabs., 21 figs., 6 appendices

Biological Effects of Neutron and Proton Irradiations. Vol. II. Proceedings of the Symposium on Biological Effects of Neutron Irradiations

International Nuclear Information System (INIS)

1964-01-01

During recent years the interest in biological effects caused by neutrons has been increasing steadily as a result of the rapid development of neutron technology and the great number of neutron sources being used. Neutrons, because of their specific physical characteristics and biological effects, form a special type of radiation hazard but, at the same time, are a prospective tool for applied radiobiology. This Symposium, held in Brookhaven at the invitation of the United States Government from 7-11 October 1963, provided an opportunity for scientists to discuss the experimental information at present available on the biological action of neutrons and to evaluate future possibilities. It was a sequel to the Symposium on Neutron Detection, Dosimetry and Standardization, which was organized by the International Atomic Energy Agency in December 1962 at Harwell. The Symposium was attended by 128 participants from 17 countries and 6 international organizations. Fifty-four papers were presented. The following subjects were discussed in various sessions: (1) Dosimetry. Estimation of absorbed dose of neutrons in biological material. (2) Biological effects of high-energy protons. (3) Cellular and genetic effects. (4) Pathology of neutron irradiation, including acute and chronic radiation syndromes (mortality, anatomical and histological changes, biochemical and metabolic disturbances) and delayed consequences. (5) Relative biological effectiveness of neutrons evaluated by different biological tests. A Panel on Biophysical Considerations in Neutron Experimentation, with special emphasis on informal discussions, was organized during the Symposium. The views of the Panel are recorded in Volume II of the Proceedings. Many reports were presented on the important subject of the relative effectiveness of the biological action of neutrons, as well as on the general pathology of neutron irradiation and the cellular and genetic effects related to it. Three survey papers considered

Data Acquisition and Linguistic Resources

Science.gov (United States)

Strassel, Stephanie; Christianson, Caitlin; McCary, John; Staderman, William; Olive, Joseph

All human language technology demands substantial quantities of data for system training and development, plus stable benchmark data to measure ongoing progress. While creation of high quality linguistic resources is both costly and time consuming, such data has the potential to profoundly impact not just a single evaluation program but language technology research in general. GALE's challenging performance targets demand linguistic data on a scale and complexity never before encountered. Resources cover multiple languages (Arabic, Chinese, and English) and multiple genres -- both structured (newswire and broadcast news) and unstructured (web text, including blogs and newsgroups, and broadcast conversation). These resources include significant volumes of monolingual text and speech, parallel text, and transcribed audio combined with multiple layers of linguistic annotation, ranging from word aligned parallel text and Treebanks to rich semantic annotation.

Mature Basin Development Portfolio Management in a Resource Constrained Environment

International Nuclear Information System (INIS)

Mandhane, J. M.; Udo, S. D.

2002-01-01

Nigerian Petroleum industry is constantly faced with management of resource constraints stemming from capital and operating budget, availability of skilled manpower, capacity of an existing surface facility, size of well assets, amount of soft and hard information, etceteras. Constrained capital forces the industry to rank subsurface resource and potential before proceeding with preparation of development scenarios. Availability of skilled manpower limits scope of integrated reservoir studies. Level of information forces technical and management to find low-risk development alternative in a limited time. Volume of either oil or natural gas or water or combination of them may be constrained due to design limits of the existing facility, or an external OPEC quota, requires high portfolio management skills.The first part of the paper statistically analyses development portfolio of a mature basin for (a) subsurface resources volume, (b) developed and undeveloped and undeveloped volumes, (c) sweating of wells, and (d) facility assets. The analysis presented conclusively demonstrates that the 80/20 is active in the statistical sample. The 80/20 refers to 80% of the effect coming from the 20% of the cause. The second part of the paper deals with how 80/20 could be applied to manage portfolio for a given set of constraints. Three application examples are discussed. Feedback on implementation of them resulting in focussed resource management with handsome rewards is documented.The statistical analysis and application examples from a mature basin form a way forward for a development portfolio management in an resource constrained environment

Physics with illustrative examples from medicine and biology

CERN Document Server

Benedek, George B

Physics: with illustrative examples from medicine and biology is a three-volume set of textbooks in introductory physics written at the calculus level and designed primarily for students with career objectives in the life sciences.

Proceedings of the Scientific Meeting on Application of Isotopes and Radiation, Book I, Agricultural, Animal and Biology

International Nuclear Information System (INIS)

Suhadi, F.; Sisworo, E.L.; Maha, M.; Ismachin, M.; Hilmy, N.; Sumatra, M.; Mugiono; Wandowo; Soebianto, Y.S

1998-01-01

The aim of the 10 t h Meeting of the Isotope and Radiation Application is to disseminate the result of research on application of nuclear techniques on agriculture, animal, biology, chemistry, environment, radiation process and industry. The meeting was held in Jakarta, 18-19 February 1998, and there were 6 invited papers and 52 papers indexed individually. This proceeding is divided by two volumes. Volume I and volume II consists of agriculture, animal, biology and chemistry, environment, radiation process and industry, respectively.(ID)

Review of dynamic optimization methods in renewable natural resource management

Science.gov (United States)

Williams, B.K.

1989-01-01

In recent years, the applications of dynamic optimization procedures in natural resource management have proliferated. A systematic review of these applications is given in terms of a number of optimization methodologies and natural resource systems. The applicability of the methods to renewable natural resource systems are compared in terms of system complexity, system size, and precision of the optimal solutions. Recommendations are made concerning the appropriate methods for certain kinds of biological resource problems.

Australian Biology Test Item Bank, Years 11 and 12. Volume II: Year 12.

Science.gov (United States)

Brown, David W., Ed.; Sewell, Jeffrey J., Ed.

This document consists of test items which are applicable to biology courses throughout Australia (irrespective of course materials used); assess key concepts within course statement (for both core and optional studies); assess a wide range of cognitive processes; and are relevant to current biological concepts. These items are arranged under…

Australian Biology Test Item Bank, Years 11 and 12. Volume I: Year 11.

Science.gov (United States)

Brown, David W., Ed.; Sewell, Jeffrey J., Ed.

This document consists of test items which are applicable to biology courses throughout Australia (irrespective of course materials used); assess key concepts within course statement (for both core and optional studies); assess a wide range of cognitive processes; and are relevant to current biological concepts. These items are arranged under…

Piecewise deterministic processes in biological models

CERN Document Server

Rudnicki, Ryszard

2017-01-01

This book presents a concise introduction to piecewise deterministic Markov processes (PDMPs), with particular emphasis on their applications to biological models. Further, it presents examples of biological phenomena, such as gene activity and population growth, where different types of PDMPs appear: continuous time Markov chains, deterministic processes with jumps, processes with switching dynamics, and point processes. Subsequent chapters present the necessary tools from the theory of stochastic processes and semigroups of linear operators, as well as theoretical results concerning the long-time behaviour of stochastic semigroups induced by PDMPs and their applications to biological models. As such, the book offers a valuable resource for mathematicians and biologists alike. The first group will find new biological models that lead to interesting and often new mathematical questions, while the second can observe how to include seemingly disparate biological processes into a unified mathematical theory, and...

Sustainability issues for resource managers.

Science.gov (United States)

Daniel L. Bottom; Gordon H. Reeves; Martha H. Brookes

1996-01-01

Throughout their history, conservation science and sustainable-yield management have failed to maintain the productivity of living resources. Repeated overexploitation of economic species, loss of biological diversity, and degradation of regional environments now call into question the economic ideas and values that have formed the foundation of scientific management...

Biological diversity in the patent system.

Directory of Open Access Journals (Sweden)

Paul Oldham

Full Text Available Biological diversity in the patent system is an enduring focus of controversy but empirical analysis of the presence of biodiversity in the patent system has been limited. To address this problem we text mined 11 million patent documents for 6 million Latin species names from the Global Names Index (GNI established by the Global Biodiversity Information Facility (GBIF and Encyclopedia of Life (EOL. We identified 76,274 full Latin species names from 23,882 genera in 767,955 patent documents. 25,595 species appeared in the claims section of 136,880 patent documents. This reveals that human innovative activity involving biodiversity in the patent system focuses on approximately 4% of taxonomically described species and between 0.8-1% of predicted global species. In this article we identify the major features of the patent landscape for biological diversity by focusing on key areas including pharmaceuticals, neglected diseases, traditional medicines, genetic engineering, foods, biocides, marine genetic resources and Antarctica. We conclude that the narrow focus of human innovative activity and ownership of genetic resources is unlikely to be in the long term interest of humanity. We argue that a broader spectrum of biodiversity needs to be opened up to research and development based on the principles of equitable benefit-sharing, respect for the objectives of the Convention on Biological Diversity, human rights and ethics. Finally, we argue that alternative models of innovation, such as open source and commons models, are required to open up biodiversity for research that addresses actual and neglected areas of human need. The research aims to inform the implementation of the 2010 Nagoya Protocol on Access to Genetic Resources and the Equitable Sharing of Benefits Arising from their Utilization and international debates directed to the governance of genetic resources. Our research also aims to inform debates under the Intergovernmental Committee on

Subcortical intelligence: caudate volume predicts IQ in healthy adults.

Science.gov (United States)

Grazioplene, Rachael G; G Ryman, Sephira; Gray, Jeremy R; Rustichini, Aldo; Jung, Rex E; DeYoung, Colin G

2015-04-01

This study examined the association between size of the caudate nuclei and intelligence. Based on the central role of the caudate in learning, as well as neuroimaging studies linking greater caudate volume to better attentional function, verbal ability, and dopamine receptor availability, we hypothesized the existence of a positive association between intelligence and caudate volume in three large independent samples of healthy adults (total N = 517). Regression of IQ onto bilateral caudate volume controlling for age, sex, and total brain volume indicated a significant positive correlation between caudate volume and intelligence, with a comparable magnitude of effect across each of the three samples. No other subcortical structures were independently associated with IQ, suggesting a specific biological link between caudate morphology and intelligence. © 2014 Wiley Periodicals, Inc.

Dynamics of mathematical models in biology bringing mathematics to life

CERN Document Server

Zazzu, Valeria; Guarracino, Mario

2016-01-01

This volume focuses on contributions from both the mathematics and life science community surrounding the concepts of time and dynamicity of nature, two significant elements which are often overlooked in modeling process to avoid exponential computations. The book is divided into three distinct parts: dynamics of genomes and genetic variation, dynamics of motifs, and dynamics of biological networks. Chapters included in dynamics of genomes and genetic variation analyze the molecular mechanisms and evolutionary processes that shape the structure and function of genomes and those that govern genome dynamics. The dynamics of motifs portion of the volume provides an overview of current methods for motif searching in DNA, RNA and proteins, a key process to discover emergent properties of cells, tissues, and organisms. The part devoted to the dynamics of biological networks covers networks aptly discusses networks in complex biological functions and activities that interpret processes in cells. Moreover, chapters i...

National hydroelectric power resources study. Preliminary inventory of hydropower resources. Volume 2. Pacific Southwest region

Energy Technology Data Exchange (ETDEWEB)

None

1979-07-01

The estimates of existing, incremental, and the undeveloped hydropower potential for all states in the various regions of the country are presented. In the Pacific Southwest region, the maximum physical potential for all sites exceeds 33,000 MW of capacity with an estimated average annual energy greater than 85,000 GWH. By comparison, these values represent about 6% of the total potential capacity and hydroelectric energy generation estimated for the entire US. Of the total capacity estimated for the region, 9900 MW has been installed. The remainder (23,200 MW) is the maximum which could be developed by upgrading and expanding existing projects (6000 MW) and by installing new hydroelectric power capacity at all potentially feasible, undeveloped sites (17,200 MW). Small-scale facilities account for less than 4% of the region's total installed capacity, but another 600 MW could be added to these and other small water resource projects. In addition, 600 MW could be installed at potentially feasible, undeveloped small-scale sites. The small-scale resource varies considerably, with the states of California and Utah having the largest potential for incremental development at existing projects in the Pacific Southwest region. States comprising the Southwest are Arizona, California, Hawaii, Nevada, and Utah.

Database Resources of the BIG Data Center in 2018.

Science.gov (United States)

2018-01-04

The BIG Data Center at Beijing Institute of Genomics (BIG) of the Chinese Academy of Sciences provides freely open access to a suite of database resources in support of worldwide research activities in both academia and industry. With the vast amounts of omics data generated at ever-greater scales and rates, the BIG Data Center is continually expanding, updating and enriching its core database resources through big-data integration and value-added curation, including BioCode (a repository archiving bioinformatics tool codes), BioProject (a biological project library), BioSample (a biological sample library), Genome Sequence Archive (GSA, a data repository for archiving raw sequence reads), Genome Warehouse (GWH, a centralized resource housing genome-scale data), Genome Variation Map (GVM, a public repository of genome variations), Gene Expression Nebulas (GEN, a database of gene expression profiles based on RNA-Seq data), Methylation Bank (MethBank, an integrated databank of DNA methylomes), and Science Wikis (a series of biological knowledge wikis for community annotations). In addition, three featured web services are provided, viz., BIG Search (search as a service; a scalable inter-domain text search engine), BIG SSO (single sign-on as a service; a user access control system to gain access to multiple independent systems with a single ID and password) and Gsub (submission as a service; a unified submission service for all relevant resources). All of these resources are publicly accessible through the home page of the BIG Data Center at http://bigd.big.ac.cn. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

"A mission-driven discipline": the growth of conservation biology.

Science.gov (United States)

Meine, Curt; Soulé, Michael; Noss, Reed E

2006-06-01

Conservation biology emerged in the mid-1980s, drawing on established disciplines and integrating them in pursuit of a coherent goal: the protection and perpetuation of the Earth's biological diversity. Opportunistic in its borrowing and application of knowledge, conservation biology had its roots within the established biological sciences and resource management disciplines but has continually incorporated insights from the empirical experience of resource managers, from the social sciences and humanities, and from diverse cultural sources. The Society for Conservation Biology (SCB) has represented the field's core constituency, while expanding that constituency in keeping with the field's integrative spirit. Conservation Biology has served as SCB's flagship publication, promoting research, dialog, debate, and application of the field's essential concepts. Over the last 20 years the field, SCB, and the journal have evolved to meet changing conservation needs, to explore gaps in our knowledge base, to incorporate new information from related fields, to build professional capacity, and to provide expanded opportunities for international participation. In turn, the field, SCB, and journal have prompted change in related fields, organizations, and publications. In its dedication to advancing the scientific foundations of biodiversity conservation and placing that science at the service of society in a world whose variety, wildness, and beauty we care for conservation biology represents both a continuation and radical reconfiguration of the traditional relationship between science and conservation.

A Curriculum Activities Guide to Water Pollution and Environmental Studies, Volume II - Appendices.

Science.gov (United States)

Hershey, John T., Ed.; And Others

This publication, Volume II of a two volume set of water pollution studies, contains seven appendices which support the studies. Appendix 1, Water Quality Parameters, consolidates the technical aspects of water quality including chemical, biological, computer program, and equipment information. Appendix 2, Implementation, outlines techniques…

Breeding system and pollination biology of the semidomesticated ...

African Journals Online (AJOL)

Breeding system and pollination biology of the semidomesticated fruit tree, Tamarindus indica L. (Leguminosae: Caesalpinioideae ): Implications for fruit production, selective breeding, and conservation of genetic resources.

Timber resource statistics for western Washington.

Science.gov (United States)

Coffin D. MacLean; Patricia M. Bassett; Glenn. Yeary

1992-01-01

This report summarizes a 1988-90 timber resource inventory of 19 counties in western Washington: Clallam, Clark, Cowlitz, Grays Harbor, Island, Jefferson, King, Kitsap, Lewis, Mason, Pacific, Pierce, San Juan, Skagit, Skamania, Snohomish, Thurston, Wahkiakum, and Whatcom. Detailed tables of forest area, timber volume, growth, mortality, and harvest are presented.

Relative biological efficiency of 592 MeV protons. Analysis of the biological effect of secondary radiation

International Nuclear Information System (INIS)

Legeay, G.; Baarli, J.

1968-01-01

The relative biological efficiency (RBE) of high energy protons is of importance because of their effects in the field of radioprotection around large accelerators and during space-flights. The nature of the interactions between 592 MeV protons and biological tissues makes it necessary to take into consideration the contribution of secondary radiation to the biological effect. Since it is not possible to obtain from a synchrotron a beam having a sufficiently large cross-section to irradiate large animals, one has to resort to certain devices concerning the mode of exposure when small laboratory animals are used. By irradiating rats individually and in groups, and by using the lethal test as a function of time, the authors show that the value of the RBE is different for animals of the same species having the same biological parameters. Thus there appears an increase in the biological effect due to secondary radiation produced in nuclear cascades which develop in a large volume, for example that of a human being. (author) [fr

Resource Allocation Model for Great Plains Regional Medical Command: Volume 1

National Research Council Canada - National Science Library

Wojcik, Barbara E; Humphrey, Rebecca J; Oakley, Carolyn L; Morrison, Scott C; Devore , Jr., Raymond B; Hassell, Harrison L

2005-01-01

.... The forecasting model may estimate future allocation of resources for each military treatment facility on a yearly or monthly basis, as well as healthcare demand for each combination of patient's...

Industrial Consortium for the Utilization of the Geopressured-Geothermal Resource. Volume 2

Energy Technology Data Exchange (ETDEWEB)

Negus-deWys, J. (ed.)

1990-03-01

The Geopressured-Geothermal Program, now in its fifteenth year, is entering the transition period to commercial use. The industry cost-shared proposals to the consortium, represented in the presentations included in these proceedings, attest to the interest developing in the industrial community in utilizing the geopressured-geothermal resource. Sixty-five participants attended these sessions, two-thirds of whom represented industry. The areas represented by cost-shared proposals include (1) thermal enhanced oil recovery, (2) direct process use of thermal energy, e.g., aquaculture and agriculture, (3) conversion of thermal energy to electricity, (4) environment related technologies, e.g., use of supercritical processes, and (5) operational proposals, e.g., a field manual for scale inhibitors. It is hoped that from this array of potential use projects, some will persist and be successful in proving the viability of using the geopressured-geothermal resource. Such industrial use of an alternative and relatively clean energy resource will benefit our nation and its people.

Biological imaging in radiation therapy: role of positron emission tomography

Energy Technology Data Exchange (ETDEWEB)

Nestle, Ursula; Hentschel, Michael; Grosu, Anca-Ligia [Departments of Radiation Oncology, University of Freiburg, Robert Koch Str. 3, 79106 Freiburg (Germany); Weber, Wolfgang [Nuclear Medicine, University of Freiburg, Robert Koch Str. 3, 79106 Freiburg (Germany)], E-mail: ursula.nestle@uniklinik-freiburg.de

2009-01-07

In radiation therapy (RT), staging, treatment planning, monitoring and evaluation of response are traditionally based on computed tomography (CT) and magnetic resonance imaging (MRI). These radiological investigations have the significant advantage to show the anatomy with a high resolution, being also called anatomical imaging. In recent years, so called biological imaging methods which visualize metabolic pathways have been developed. These methods offer complementary imaging of various aspects of tumour biology. To date, the most prominent biological imaging system in use is positron emission tomography (PET), whose diagnostic properties have clinically been evaluated for years. The aim of this review is to discuss the valences and implications of PET in RT. We will focus our evaluation on the following topics: the role of biological imaging for tumour tissue detection/delineation of the gross tumour volume (GTV) and for the visualization of heterogeneous tumour biology. We will discuss the role of fluorodeoxyglucose-PET in lung and head and neck cancer and the impact of amino acids (AA)-PET in target volume delineation of brain gliomas. Furthermore, we summarize the data of the literature about tumour hypoxia and proliferation visualized by PET. We conclude that, regarding treatment planning in radiotherapy, PET offers advantages in terms of tumour delineation and the description of biological processes. However, to define the real impact of biological imaging on clinical outcome after radiotherapy, further experimental, clinical and cost/benefit analyses are required. (topical review)

Biological imaging in radiation therapy: role of positron emission tomography.

Science.gov (United States)

Nestle, Ursula; Weber, Wolfgang; Hentschel, Michael; Grosu, Anca-Ligia

2009-01-07

In radiation therapy (RT), staging, treatment planning, monitoring and evaluation of response are traditionally based on computed tomography (CT) and magnetic resonance imaging (MRI). These radiological investigations have the significant advantage to show the anatomy with a high resolution, being also called anatomical imaging. In recent years, so called biological imaging methods which visualize metabolic pathways have been developed. These methods offer complementary imaging of various aspects of tumour biology. To date, the most prominent biological imaging system in use is positron emission tomography (PET), whose diagnostic properties have clinically been evaluated for years. The aim of this review is to discuss the valences and implications of PET in RT. We will focus our evaluation on the following topics: the role of biological imaging for tumour tissue detection/delineation of the gross tumour volume (GTV) and for the visualization of heterogeneous tumour biology. We will discuss the role of fluorodeoxyglucose-PET in lung and head and neck cancer and the impact of amino acids (AA)-PET in target volume delineation of brain gliomas. Furthermore, we summarize the data of the literature about tumour hypoxia and proliferation visualized by PET. We conclude that, regarding treatment planning in radiotherapy, PET offers advantages in terms of tumour delineation and the description of biological processes. However, to define the real impact of biological imaging on clinical outcome after radiotherapy, further experimental, clinical and cost/benefit analyses are required.

Commentary: Biochemistry and Molecular Biology Educators Launch National Network

Science.gov (United States)

Bailey, Cheryl; Bell, Ellis; Johnson, Margaret; Mattos, Carla; Sears, Duane; White, Harold B.

2010-01-01

The American Society of Biochemistry and Molecular Biology (ASBMB) has launched an National Science Foundation (NSF)-funded 5 year project to support biochemistry and molecular biology educators learning what and how students learn. As a part of this initiative, hundreds of life scientists will plan and develop a rich central resource for…

Studies on Monitoring and Tracking Genetic Resources: An Executive Summary

DEFF Research Database (Denmark)

Garrity, GM; Thompson, LM; Ussery, David

2009-01-01

The principles underlying fair and equitable sharing of benefits derived from the utilization of genetic resources are set out in Article 15 of the UN Convention on Biological Diversity, which stipulate that access to genetic resources is subject to the prior informed consent of the country where...

Shoreline clean-up methods : biological treatments

Energy Technology Data Exchange (ETDEWEB)

Massoura, S.T. [Oil Spill Response Limited, Southampton (United Kingdom)

2009-07-01

The cleanup of oil spills in shoreline environments is a challenging issue worldwide. Oil spills receive public and media attention, particularly in the event of a coastal impact. It is important to evaluate the efficiency and effectiveness of cleanup methods when defining the level of effort and consequences that are appropriate to remove or treat different types of oil on different shoreline substrates. Of the many studies that have compared different mechanical, chemical and biological treatments for their effectiveness on various types of oil, biological techniques have received the most attention. For that reason, this paper evaluated the effectiveness and effects of shoreline cleanup methods using biological techniques. It summarized data from field experiments and oil spill incidents, including the Exxon Valdez, Sea Empress, Prestige, Grand Eagle, Nakhodka, Guanabara Bay and various Gulf war oil spills. Five major shoreline types were examined, notably rocky intertidal, cobble/pebble/gravel, sand/mud, saltmarsh, and mangrove/sea-grass. The biological techniques that were addressed were nutrient enrichment, hydrocarbon-utilizing bacteria, vegetable oil biosolvents, plants, surf washing, oil-particle interactions and natural attenuation. The study considered the oil type, volume and fate of stranded oil, location of coastal materials, extent of pollution and the impact of biological techniques. The main factors that affect biodegradation of hydrocarbons are the volume, chemical composition and weathering state of the petroleum product as well as the temperature, oxygen availability of nutrients, water salinity, pH level, water content, and microorganisms in the shoreline environment. The interaction of these factors also affect the biodegradation of oil. It was concluded that understanding the fate of stranded oil can help in the development of techniques that improve the weathering and degradation of oil on complex shoreline substrates. 39 refs.

Recommendations for sampling for prevention of hazards in civil defense. On analytics of chemical, biological and radioactive contaminations. Brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling

International Nuclear Information System (INIS)

Bachmann, Udo; Biederbick, Walter; Derakshani, Nahid

2010-01-01

The recommendation for sampling for prevention of hazards in civil defense is describing the analytics of chemical, biological and radioactive contaminations and includes detail information on the sampling, protocol preparation and documentation procedures. The volume includes a separate brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling.

Natural resource damage assessment models for Great Lakes, coastal, and marine environments

International Nuclear Information System (INIS)

French, D.P.; Reed, M.

1993-01-01

A computer model of the physical fates, biological effects, and economic damages resulting from releases of oil and other hazardous materials has been developed by Applied Science Associates to be used in Type A natural resource damage assessments under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Natural resource damage assessment models for great lakes environments and for coastal and marine environments will become available. A coupled geographical information system allows gridded representation of complex coastal boundaries, variable bathymetry, shoreline types, and multiple biological habitats. The physical and biological models are three dimensional. Direct mortality from toxic concentrations and oiling, impacts of habitat loss, and food web losses are included in the model. Estimation of natural resource damages is based both on the lost value of injured resources and on the costs of restoring or replacing those resources. The models are implemented on a personal computer, with a VGA graphical user interface. Following public review, the models will become a formal part of the US regulatory framework. The models are programmed in a modular and generic fashion, to facilitate transportability and application to new areas. The model has several major components. Physical fates and biological effects submodels estimate impacts or injury resulting from a spill. The hydrodynamic submodel calculates currents that transport contaminant(s) or organisms. The compensable value submodel values injuries to help assess damages. The restoration submodel determines what restoration actions will most cost-effectively reduce injuries as measured by compensable values. Injury and restoration costs are assessed for each of a series of habitats (environments) affected by the spill. Environmental, chemical, and biological databases supply required information to the model for computing fates and effects (injury)

Integrated resource management of biomass

International Nuclear Information System (INIS)

Goodwin, E.R.

1992-01-01

An overview is presented of the use of biomass, with emphasis on peat, as an alternative energy source, from an integrated resource management perspective. Details are provided of the volume of the peat resource, economics of peat harvesting, and constraints to peat resource use, which mainly centre on its high water content. Use of waste heat to dry peat can increase the efficiency of peat burning for electric power generation, and new technologies such as gasification and turbo expanders may also find utilization. The burning or gasification of biomass will release no more carbon dioxide to the atmosphere than other fuels, has less sulfur content than solid fuels. The removal of peat reduces methane emissions and allows use of produced carbon dioxide for horticulture and ash for fertilizer, and creates space that may be used for forestry or agricultural biomass growth. 38 refs

Queensland Museum Online Learning Resources

Science.gov (United States)

Bauer, Adriana

2009-01-01

This article evaluates three online educational resources on the Queensland Museum website in terms of their use of ICTs in science education; how they relate to the Queensland Middle School Science Curriculum and the Senior Biology, Marine Studies, Science 21 syllabuses; their visual appeal and level of student engagement; the appropriateness of…

Turning Video Resource Management into Cloud Computing

Directory of Open Access Journals (Sweden)

Weili Kou

2016-07-01

Full Text Available Big data makes cloud computing more and more popular in various fields. Video resources are very useful and important to education, security monitoring, and so on. However, issues of their huge volumes, complex data types, inefficient processing performance, weak security, and long times for loading pose challenges in video resource management. The Hadoop Distributed File System (HDFS is an open-source framework, which can provide cloud-based platforms and presents an opportunity for solving these problems. This paper presents video resource management architecture based on HDFS to provide a uniform framework and a five-layer model for standardizing the current various algorithms and applications. The architecture, basic model, and key algorithms are designed for turning video resources into a cloud computing environment. The design was tested by establishing a simulation system prototype.

Timber resource statistics for the Olympic Peninsula, Washington.

Science.gov (United States)

Patricia M. Bassett; Daniel D. Oswald

1961-01-01

This report summarizes a 1978-79 timber resource inventory of five counties in the Olympic Peninsula of Washington: Clallam, Grays Harbor, Jefferson, Mason, and Thurston. Detailed tables of forest area, timber volume, growth, mortality, and harvest are presented.

The Montpellier Leishmania Collection, from a Laboratory Collection to a Biological Resource Center: A 39-Year-Long Story.

Science.gov (United States)

Pratlong, Francine; Balard, Yves; Lami, Patrick; Talignani, Loïc; Ravel, Christophe; Dereure, Jacques; Lefebvre, Michèle; Serres, Ghislaine; Bastien, Patrick; Dedet, Jean-Pierre

2016-12-01

We report the development of a laboratory collection of Leishmania that was initiated in 1975 and, after 39 years, has become an international Biological Resource Center (BRC-Leish, Montpellier, France, BioBank No. BB-0033-00052), which includes 6353 strains belonging to 36 Leishmania taxa. This is a retrospective analysis of the technical and organizational changes that have been adopted over time to take into account the technological advances and related modifications in the collection management and quality system. The technical improvements concerned the culture and cryopreservation techniques, strain identification by isoenzymatic and molecular techniques, data computerization and quality management to meet the changes in international standards, and in the cryogenic and microbiological safety procedures. The BRC is working toward obtaining the NF-S 96-900 certification in the coming years. Our long-term expertise in Leishmania storage and typing and collection maintenance should encourage field epidemiologists and clinical practitioners in endemic countries to secure their own strain collection with the help of the French BRC-Leish.

Women are underrepresented on the editorial boards of journals in environmental biology and natural resource management

Directory of Open Access Journals (Sweden)

Alyssa H. Cho

2014-08-01

Full Text Available Despite women earning similar numbers of graduate degrees as men in STEM disciplines, they are underrepresented in upper level positions in both academia and industry. Editorial board memberships are an important example of such positions; membership is both a professional honor in recognition of achievement and an opportunity for professional advancement. We surveyed 10 highly regarded journals in environmental biology, natural resource management, and plant sciences to quantify the number of women on their editorial boards and in positions of editorial leadership (i.e., Associate Editors and Editors-in-Chief from 1985 to 2013. We found that during this time period only 16% of subject editors were women, with more pronounced disparities in positions of editorial leadership. Although the trend was towards improvement over time, there was surprising variation between journals, including those with similar disciplinary foci. While demographic changes in academia may reduce these disparities over time, we argue journals should proactively strive for gender parity on their editorial boards. This will both increase the number of women afforded the opportunities and benefits that accompany board membership and increase the number of role models and potential mentors for early-career scientists and students.

INEL environmental characterization report. Volume III. Appendices E-H

International Nuclear Information System (INIS)

1984-09-01

This volume contains the following appendices: (1) INEL subsurface hydrology; (2) cultural resources assessment of two study areas on the INEL; (3) description of INEL facilities; and (4) effluent measurements and environmental monitoring programs

Biometry: the principles and practice of statistics in biological research

National Research Council Canada - National Science Library

Sokal, R.R; Rohlf, F.J

1969-01-01

In this introductory textbook, with its companion volume of tables, the authors provide a balanced presentation of statistical methodology for the descriptive, experimental, and analytical study of biological phenomena...

Coastal Resources Atlas: Long Island: BIRDS (Bird Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains sensitive biological resource data for wading birds, shorebirds, waterfowl, raptors, diving birds, seabirds, passerine birds, and gulls and...

Plant Systems Biology at the Single-Cell Level.

Science.gov (United States)

Libault, Marc; Pingault, Lise; Zogli, Prince; Schiefelbein, John

2017-11-01

Our understanding of plant biology is increasingly being built upon studies using 'omics and system biology approaches performed at the level of the entire plant, organ, or tissue. Although these approaches open new avenues to better understand plant biology, they suffer from the cellular complexity of the analyzed sample. Recent methodological advances now allow plant scientists to overcome this limitation and enable biological analyses of single-cells or single-cell-types. Coupled with the development of bioinformatics and functional genomics resources, these studies provide opportunities for high-resolution systems analyses of plant phenomena. In this review, we describe the recent advances, current challenges, and future directions in exploring the biology of single-cells and single-cell-types to enhance our understanding of plant biology as a system. Copyright © 2017 Elsevier Ltd. All rights reserved.

Estimation of tumor volume and its prognostic significance to study the biological behavior of carcinoma of cervix

Directory of Open Access Journals (Sweden)

Leelavathi Dawson

2016-01-01

Results: The median age of the patients in this group was 47.5 years, with a range of 30–80 years. The major histological type of carcinoma among 40 cases is squamous cell carcinoma (SCC (in 90% of cases, and 10% had adenocarcinoma. Pathological staging of the carcinoma cervix showed stage Ib, IIa, IIb, and IVa (35%, 20%, 40%, and 5%. Tumor volume estimated on pathological specimens of 40 cases ranged from 230 cumm to 49,760 cumm with a mean of 14,844 cumm. 12 (30% cases had tumor volume more than 15,000 cumm, 12 (30% cases had tumor volume <5000 cumm and 16 (40% cases had tumor volume between 5000 and 15,000 cumm. 17% of the tumors with tumor volume <5000 cumm showed lymph node metastases, whereas 67% (out of 12cases of cases with tumor volume more than 15,000 cumm showed lymph node metastases. 67% of the tumors with tumor volume <5000 cumm showed 0/4 organs involvement, whereas all cases with tumor volume more than 15,000 cumm showed more than one organ involvement among vagina, uterus, parametrium or bladder/rectum. Fibronectin positivity was seen in 22 out of 44 cases (55%. Macrophages were seen surrounding the group of tumor cells by LN5 immunostaining. Conclusion: Tumor volume can be considered as an independent prognostic factor to assess the spread of the tumor. Cases with tumor volume <5000 cumm show low risk in terms of parametrial involvement and lymph node metastasis and those with tumor volume more than 15,000 cumm showed more organ spread. Fibronectin positivity carries some importance in low-risk cases. For macrophages, further detailed study needs to be carried out.

Recommendations for designing and conducting veterinary clinical pathology biologic variation studies

DEFF Research Database (Denmark)

Freeman, Kathleen P; Baral, Randolph M; Dhand, Navneet K

2017-01-01

The recent creation of a veterinary clinical pathology biologic variation website has highlighted the need to provide recommendations for future studies of biologic variation in animals in order to help standardize and improve the quality of published information and to facilitate review......). These recommendations provide a valuable resource for clinicians, laboratorians, and researchers interested in conducting studies of biologic variation and in determining the quality of studies of biologic variation in veterinary laboratory testing....

Novel genetic loci associated with hippocampal volume.

Science.gov (United States)

Hibar, Derrek P; Adams, Hieab H H; Jahanshad, Neda; Chauhan, Ganesh; Stein, Jason L; Hofer, Edith; Renteria, Miguel E; Bis, Joshua C; Arias-Vasquez, Alejandro; Ikram, M Kamran; Desrivières, Sylvane; Vernooij, Meike W; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos; Aribisala, Benjamin S; Armstrong, Nicola J; Athanasiu, Lavinia; Axelsson, Tomas; Beecham, Ashley H; Beiser, Alexa; Bernard, Manon; Blanton, Susan H; Bohlken, Marc M; Boks, Marco P; Bralten, Janita; Brickman, Adam M; Carmichael, Owen; Chakravarty, M Mallar; Chen, Qiang; Ching, Christopher R K; Chouraki, Vincent; Cuellar-Partida, Gabriel; Crivello, Fabrice; Den Braber, Anouk; Doan, Nhat Trung; Ehrlich, Stefan; Giddaluru, Sudheer; Goldman, Aaron L; Gottesman, Rebecca F; Grimm, Oliver; Griswold, Michael E; Guadalupe, Tulio; Gutman, Boris A; Hass, Johanna; Haukvik, Unn K; Hoehn, David; Holmes, Avram J; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Jørgensen, Kjetil N; Karbalai, Nazanin; Kasperaviciute, Dalia; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H; Liewald, David C M; Lopez, Lorna M; Luciano, Michelle; Macare, Christine; Marquand, Andre F; Matarin, Mar; Mather, Karen A; Mattheisen, Manuel; McKay, David R; Milaneschi, Yuri; Muñoz Maniega, Susana; Nho, Kwangsik; Nugent, Allison C; Nyquist, Paul; Loohuis, Loes M Olde; Oosterlaan, Jaap; Papmeyer, Martina; Pirpamer, Lukas; Pütz, Benno; Ramasamy, Adaikalavan; Richards, Jennifer S; Risacher, Shannon L; Roiz-Santiañez, Roberto; Rommelse, Nanda; Ropele, Stefan; Rose, Emma J; Royle, Natalie A; Rundek, Tatjana; Sämann, Philipp G; Saremi, Arvin; Satizabal, Claudia L; Schmaal, Lianne; Schork, Andrew J; Shen, Li; Shin, Jean; Shumskaya, Elena; Smith, Albert V; Sprooten, Emma; Strike, Lachlan T; Teumer, Alexander; Tordesillas-Gutierrez, Diana; Toro, Roberto; Trabzuni, Daniah; Trompet, Stella; Vaidya, Dhananjay; Van der Grond, Jeroen; Van der Lee, Sven J; Van der Meer, Dennis; Van Donkelaar, Marjolein M J; Van Eijk, Kristel R; Van Erp, Theo G M; Van Rooij, Daan; Walton, Esther; Westlye, Lars T; Whelan, Christopher D; Windham, Beverly G; Winkler, Anderson M; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Wolfers, Thomas; Yanek, Lisa R; Yang, Jingyun; Zijdenbos, Alex; Zwiers, Marcel P; Agartz, Ingrid; Almasy, Laura; Ames, David; Amouyel, Philippe; Andreassen, Ole A; Arepalli, Sampath; Assareh, Amelia A; Barral, Sandra; Bastin, Mark E; Becker, Diane M; Becker, James T; Bennett, David A; Blangero, John; van Bokhoven, Hans; Boomsma, Dorret I; Brodaty, Henry; Brouwer, Rachel M; Brunner, Han G; Buckner, Randy L; Buitelaar, Jan K; Bulayeva, Kazima B; Cahn, Wiepke; Calhoun, Vince D; Cannon, Dara M; Cavalleri, Gianpiero L; Cheng, Ching-Yu; Cichon, Sven; Cookson, Mark R; Corvin, Aiden; Crespo-Facorro, Benedicto; Curran, Joanne E; Czisch, Michael; Dale, Anders M; Davies, Gareth E; De Craen, Anton J M; De Geus, Eco J C; De Jager, Philip L; De Zubicaray, Greig I; Deary, Ian J; Debette, Stéphanie; DeCarli, Charles; Delanty, Norman; Depondt, Chantal; DeStefano, Anita; Dillman, Allissa; Djurovic, Srdjan; Donohoe, Gary; Drevets, Wayne C; Duggirala, Ravi; Dyer, Thomas D; Enzinger, Christian; Erk, Susanne; Espeseth, Thomas; Fedko, Iryna O; Fernández, Guillén; Ferrucci, Luigi; Fisher, Simon E; Fleischman, Debra A; Ford, Ian; Fornage, Myriam; Foroud, Tatiana M; Fox, Peter T; Francks, Clyde; Fukunaga, Masaki; Gibbs, J Raphael; Glahn, David C; Gollub, Randy L; Göring, Harald H H; Green, Robert C; Gruber, Oliver; Gudnason, Vilmundur; Guelfi, Sebastian; Håberg, Asta K; Hansell, Narelle K; Hardy, John; Hartman, Catharina A; Hashimoto, Ryota; Hegenscheid, Katrin; Heinz, Andreas; Le Hellard, Stephanie; Hernandez, Dena G; Heslenfeld, Dirk J; Ho, Beng-Choon; Hoekstra, Pieter J; Hoffmann, Wolfgang; Hofman, Albert; Holsboer, Florian; Homuth, Georg; Hosten, Norbert; Hottenga, Jouke-Jan; Huentelman, Matthew; Hulshoff Pol, Hilleke E; Ikeda, Masashi; Jack, Clifford R; Jenkinson, Mark; Johnson, Robert; Jönsson, Erik G; Jukema, J Wouter; Kahn, René S; Kanai, Ryota; Kloszewska, Iwona; Knopman, David S; Kochunov, Peter; Kwok, John B; Lawrie, Stephen M; Lemaître, Hervé; Liu, Xinmin; Longo, Dan L; Lopez, Oscar L; Lovestone, Simon; Martinez, Oliver; Martinot, Jean-Luc; Mattay, Venkata S; McDonald, Colm; McIntosh, Andrew M; McMahon, Francis J; McMahon, Katie L; Mecocci, Patrizia; Melle, Ingrid; Meyer-Lindenberg, Andreas; Mohnke, Sebastian; Montgomery, Grant W; Morris, Derek W; Mosley, Thomas H; Mühleisen, Thomas W; Müller-Myhsok, Bertram; Nalls, Michael A; Nauck, Matthias; Nichols, Thomas E; Niessen, Wiro J; Nöthen, Markus M; Nyberg, Lars; Ohi, Kazutaka; Olvera, Rene L; Ophoff, Roel A; Pandolfo, Massimo; Paus, Tomas; Pausova, Zdenka; Penninx, Brenda W J H; Pike, G Bruce; Potkin, Steven G; Psaty, Bruce M; Reppermund, Simone; Rietschel, Marcella; Roffman, Joshua L; Romanczuk-Seiferth, Nina; Rotter, Jerome I; Ryten, Mina; Sacco, Ralph L; Sachdev, Perminder S; Saykin, Andrew J; Schmidt, Reinhold; Schmidt, Helena; Schofield, Peter R; Sigursson, Sigurdur; Simmons, Andrew; Singleton, Andrew; Sisodiya, Sanjay M; Smith, Colin; Smoller, Jordan W; Soininen, Hilkka; Steen, Vidar M; Stott, David J; Sussmann, Jessika E; Thalamuthu, Anbupalam; Toga, Arthur W; Traynor, Bryan J; Troncoso, Juan; Tsolaki, Magda; Tzourio, Christophe; Uitterlinden, Andre G; Hernández, Maria C Valdés; Van der Brug, Marcel; van der Lugt, Aad; van der Wee, Nic J A; Van Haren, Neeltje E M; van 't Ent, Dennis; Van Tol, Marie-Jose; Vardarajan, Badri N; Vellas, Bruno; Veltman, Dick J; Völzke, Henry; Walter, Henrik; Wardlaw, Joanna M; Wassink, Thomas H; Weale, Michael E; Weinberger, Daniel R; Weiner, Michael W; Wen, Wei; Westman, Eric; White, Tonya; Wong, Tien Y; Wright, Clinton B; Zielke, Ronald H; Zonderman, Alan B; Martin, Nicholas G; Van Duijn, Cornelia M; Wright, Margaret J; Longstreth, W T; Schumann, Gunter; Grabe, Hans J; Franke, Barbara; Launer, Lenore J; Medland, Sarah E; Seshadri, Sudha; Thompson, Paul M; Ikram, M Arfan

2017-01-18

The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (r g =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.

7th World Congress on Nature and Biologically Inspired Computing

CERN Document Server

Engelbrecht, Andries; Abraham, Ajith; Plessis, Mathys; Snášel, Václav; Muda, Azah

2016-01-01

World Congress on Nature and Biologically Inspired Computing (NaBIC) is organized to discuss the state-of-the-art as well as to address various issues with respect to Nurturing Intelligent Computing Towards Advancement of Machine Intelligence. This Volume contains the papers presented in the Seventh World Congress (NaBIC’15) held in Pietermaritzburg, South Africa during December 01-03, 2015. The 39 papers presented in this Volume were carefully reviewed and selected. The Volume would be a valuable reference to researchers, students and practitioners in the computational intelligence field.

Patient Characteristics, Health Care Resource Utilization, and Costs Associated with Treatment-Regimen Failure with Biologics in the Treatment of Psoriasis.

Science.gov (United States)

Foster, Shonda A; Zhu, Baojin; Guo, Jiaying; Nikai, Enkeleida; Ojeh, Clement; Malatestinic, William; Goldblum, Orin; Kornberg, Lori J; Wu, Jashin J

2016-04-01

Psoriasis is a chronic, incurable, and immune-mediated skin disorder that is characterized by erythematous scaly papules and plaques. Understanding of psoriasis at the molecular level has led to the development of biologic agents that target disease-specific inflammatory mediators in psoriatic lesions. Biologic agents have become important components of the psoriasis armamentarium, but some patients become refractory to these agents over time or fail to respond to subsequent biologics. To (a) evaluate demographic and clinical characteristics of psoriasis patients who have treatment patterns suggestive of failure to a newly initiated biologic agent (treatment-regimen failures) compared with those who do not (non-treatment-regimen failures) and (b) to assess health care-related resource utilization and costs in non-treatment-regimen failures and treatment-regimen failures. In this retrospective observational cohort study, patients were selected from the MarketScan claims database of commercially insured individuals and individuals with Medicare supplemental insurance. The index event was a newly initiated biologic agent for the treatment of psoriasis (etanercept, adalimumab, ustekinumab, or infliximab) between January 2010 and December 2011. The analysis included psoriasis patients aged ≥ 18 years with ≥ 1 prescription claim for a biologic and continuous enrollment 12 months pre- and post-index date. Patients with claims for a biologic in the pre-index period were excluded. Patients were divided into treatment-regimen-failure and non-treatment-regimen-failure groups based on their treatment patterns post-index date. The treatment-regimen-failure group included patients who switched to another biologic, discontinued the biologic without restarting, increased the dose of the biologic, or augmented treatment with a nontopical psoriasis medication during the post-index period. Between-group patient characteristics and medication use were compared using analysis of

Managing common resources in local and global systems. Applying theory across scales

Energy Technology Data Exchange (ETDEWEB)

Karlsson, Sylvia [ed.

1998-12-31

The main point brought forward in this publication is the productiveness of applying theoretical elements, developed within common property resource (CPR) literature, to a broader field of cases on different scales. The common framework for the contributions is a series of seminars held at the Department of Water and Environmental Studies in the spring of 1996, covering expanding work during the last decade on common property resource (CPR) management. It is obvious that there were a broad range of definitions of the concept CPR in the literature. The common pool/property resource concepts are both used, often depending on the resource studied, and authors in this volume have used both terms accordingly. Certain points are raised from empirical cases presented in this volume that are partly missing or not thoroughly stressed in other work in the area of CPR management and which crystallized much clearer when contrasting the situation for cases from different scales. Separate abstracts have been performed for five of the seven contributions

Managing common resources in local and global systems. Applying theory across scales

Energy Technology Data Exchange (ETDEWEB)

Karlsson, Sylvia [ed.

1997-12-31

The main point brought forward in this publication is the productiveness of applying theoretical elements, developed within common property resource (CPR) literature, to a broader field of cases on different scales. The common framework for the contributions is a series of seminars held at the Department of Water and Environmental Studies in the spring of 1996, covering expanding work during the last decade on common property resource (CPR) management. It is obvious that there were a broad range of definitions of the concept CPR in the literature. The common pool/property resource concepts are both used, often depending on the resource studied, and authors in this volume have used both terms accordingly. Certain points are raised from empirical cases presented in this volume that are partly missing or not thoroughly stressed in other work in the area of CPR management and which crystallized much clearer when contrasting the situation for cases from different scales. Separate abstracts have been performed for five of the seven contributions

The status of human and material resources used in teaching ...

African Journals Online (AJOL)

The study explored the status of human and material resources used in teaching biology in public schools in Ilorin. A descriptive survey method was adopted. All senior school students in Ilorin constituted the population, out of which 20 secondary schools were randomly selected. A checklist tagged Inventory of Resources ...

Coastal Resources Atlas: Long Island: FISH (Fish Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains sensitive biological resource data for marine, estuarine, anadromous, and freshwater fish species for Long Island, New York. Vector polygons...

European Society for Radiation Biology 21. annual meeting

International Nuclear Information System (INIS)

1988-01-01

The volume contains about 100 abstracts of lectures presented to the conference covering a large variety of topics like: Radiobiology as a base for radiotherapy, radiation carcinogenesis and cellular effects, late and secondary effects of radiotherapy, radioprotection and radiosensitization, heavy ions in radiobiology and space research, microdosimetry and biological dosimetry, radiation effects on the mature and the developing central nervous system, DNA damage and repair and cellular mutations, the imact of radiation on the environment, free radicals in radiation biology

US and Russian Cooperation in Space Biology and Medicine

Science.gov (United States)

Sawin, C.F.; Hanson, S.I.; House, N.G.; Pestov, I.D.

2009-01-01

This slide presentation concerns the 5th volume of a joint publication that describes the cooperation between the United States and Russia in research into space biology and medicine. Each of the chapters is briefly summarized.

Set membership experimental design for biological systems

Directory of Open Access Journals (Sweden)

Marvel Skylar W

2012-03-01

Full Text Available Abstract Background Experimental design approaches for biological systems are needed to help conserve the limited resources that are allocated for performing experiments. The assumptions used when assigning probability density functions to characterize uncertainty in biological systems are unwarranted when only a small number of measurements can be obtained. In these situations, the uncertainty in biological systems is more appropriately characterized in a bounded-error context. Additionally, effort must be made to improve the connection between modelers and experimentalists by relating design metrics to biologically relevant information. Bounded-error experimental design approaches that can assess the impact of additional measurements on model uncertainty are needed to identify the most appropriate balance between the collection of data and the availability of resources. Results In this work we develop a bounded-error experimental design framework for nonlinear continuous-time systems when few data measurements are available. This approach leverages many of the recent advances in bounded-error parameter and state estimation methods that use interval analysis to generate parameter sets and state bounds consistent with uncertain data measurements. We devise a novel approach using set-based uncertainty propagation to estimate measurement ranges at candidate time points. We then use these estimated measurements at the candidate time points to evaluate which candidate measurements furthest reduce model uncertainty. A method for quickly combining multiple candidate time points is presented and allows for determining the effect of adding multiple measurements. Biologically relevant metrics are developed and used to predict when new data measurements should be acquired, which system components should be measured and how many additional measurements should be obtained. Conclusions The practicability of our approach is illustrated with a case study. This

Space Biology in the 21st century

Science.gov (United States)

Halstead, Thora W.; Krauss, Robert W.

1990-01-01

Space Biology is poised to make significant contributions to science in the next century. A carefully crafted, but largely ground-based, program in the United States has evolved major questions that require answers through experiments in space. Science, scientists, and the new long-term spacecrafts designed by NASA will be available for the first time to mount a serious Space Biology effort. The scientific challenge is of such importance that success will provide countless benefits to biologically dependent areas such as medicine, food, and commerce in the decades ahead. The international community is rapidly expanding its role in this field. The United States should generate the resources that will allow progress in Space Biology to match the recognized progress made in aeronautics and the other space sciences.

[Evaluation of comprehensive capacity of resources and environments in Poyang Lake Eco-economic Zone].

Science.gov (United States)

Song, Yan-Chun; Yu, Dan

2014-10-01

With the development of the society and economy, the contradictions among population, resources and environment are increasingly worse. As a result, the capacity of resources and environment becomes one of the focal issues for many countries and regions. Through investigating and analyzing the present situation and the existing problems of resources and environment in Poyang Lake Eco-economic Zone, seven factors were chosen as the evaluation criterion layer, namely, land resources, water resources, biological resources, mineral resources, ecological-geological environment, water environment and atmospheric environment. Based on the single factor evaluation results and with the county as the evaluation unit, the comprehensive capacity of resources and environment was evaluated by using the state space method in Poyang Lake Eco-economic Zone. The results showed that it boasted abundant biological resources, quality atmosphere and water environment, and relatively stable geological environment, while restricted by land resource, water resource and mineral resource. Currently, although the comprehensive capacity of the resources and environments in Poyang Lake Eco-economic Zone was not overloaded as a whole, it has been the case in some counties/districts. State space model, with clear indication and high accuracy, could serve as another approach to evaluating comprehensive capacity of regional resources and environment.

Volume distribution in saw-timber types in the ponderosa pine region.

Science.gov (United States)

Stephen N. Wyckoff

1939-01-01

The forest survey, a Nation-wide project authorized by Congress in 1928, consists of a complete and detailed investigation of the country's present and future forest resources in five major parts: (1) an inventory of the country's existing forest resources in terms of areas occupied by forest-cover types and of timber volumes, by species, in board feet and...

Coastal Resources Atlas: Long Island: INVERT (Invertebrate Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains sensitive biological resource data for coastal, estuarine, and marine invertebrate species for Long Island, New York. Vector polygons in this...

Coastal Resources Atlas: Long Island: HABITATS (Habitat Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains sensitive biological resource data for sensitive/rare coastal plants and submerged aquatic vegetation (SAV) for Long Island, New York. Vector...

2016 Billion-Ton Report: Advancing Domestic Resources for a Thriving Bioeconomy

Energy Technology Data Exchange (ETDEWEB)

None

2016-07-06

This product builds on previous efforts, namely the 2005 Billion-Ton Study (BTS) and the 2011 U.S. Billion-Ton Update (BT2).With each report, greater perspective is gained on the potential of biomass resources to contribute to a national energy strategy. Similarly, each successive report introduces new questions regarding commercialization challenges. BTS quantified the broad biophysical potential of biomass nationally, and BT2 elucidated the potential economic availability of these resources. These reports clearly established the potential availability of up to one billion tons of biomass resources nationally. However, many questions remain, including but not limited to crop yields, climate change impacts, logistical operations, and systems integration across production, harvest, and conversion. The present report aims to address many of these questions through empirically modeled energy crop yields, scenario analysis of resources delivered to biorefineries, and the addition of new feedstocks. Volume 2 of the 2016 Billion-Ton Report is expected to be released by the end of 2016. It seeks to evaluate environmental sustainability indicators of select scenarios from volume 1 and potential climate change impacts on future supplies.

Predictors of resource utilization in transsphenoidal surgery for Cushing disease.

Science.gov (United States)

Little, Andrew S; Chapple, Kristina

2013-08-01

The short-term cost associated with subspecialized surgical care is an increasingly important metric and economic concern. This study sought to determine factors associated with hospital charges in patients undergoing transsphenoidal surgery for Cushing disease in an effort to identify the drivers of resource utilization. The authors analyzed the Nationwide Inpatient Sample (NIS) hospital discharge database from 2007 to 2009 to determine factors that influenced hospital charges in patients who had undergone transsphenoidal surgery for Cushing disease. The NIS discharge database approximates a 20% sample of all inpatient admissions to nonfederal US hospitals. A multistep regression model was developed that adjusted for patient demographics, acuity measures, comorbidities, hospital characteristics, and complications. In 116 hospitals, 454 transsphenoidal operations were performed. The mean hospital charge was $48,272 ± $32,060. A multivariate regression model suggested that the primary driver of resource utilization was length of stay (LOS), followed by surgeon volume, hospital characteristics, and postoperative complications. A 1% increase in LOS increased hospital charges by 0.60%. Patient charges were 13% lower when performed by high-volume surgeons compared with low-volume surgeons and 22% lower in large hospitals compared with small hospitals. Hospital charges were 12% lower in cases with no postoperative neurological complications. The proposed model accounted for 46% of hospital charge variance. This analysis of hospital charges in transsphenoidal surgery for Cushing disease suggested that LOS, hospital characteristics, surgeon volume, and postoperative complications are important predictors of resource utilization. These findings may suggest opportunities for improvement.

Bringing the physical sciences into your cell biology research.

Science.gov (United States)

Robinson, Douglas N; Iglesias, Pablo A

2012-11-01

Historically, much of biology was studied by physicists and mathematicians. With the advent of modern molecular biology, a wave of researchers became trained in a new scientific discipline filled with the language of genes, mutants, and the central dogma. These new molecular approaches have provided volumes of information on biomolecules and molecular pathways from the cellular to the organismal level. The challenge now is to determine how this seemingly endless list of components works together to promote the healthy function of complex living systems. This effort requires an interdisciplinary approach by investigators from both the biological and the physical sciences.

Exploring Nectar Biology To Learn about Pollinators.

Science.gov (United States)

LaBare, Kelly M.; Broyles, Steven B.; Klotz, R. Lawrence

2000-01-01

Discusses the importance of studying nectar biology. Describes how to extract nectar from various flowers, measure nectar volume, determine sugar concentration, and determine caloric value per nectar sample. These data are then related to hummingbird energetics to determine how many flowers are required to supply the pollinator with its caloric…

Do-it-yourself biology: challenges and promises for an open science and technology movement.

Science.gov (United States)

Landrain, Thomas; Meyer, Morgan; Perez, Ariel Martin; Sussan, Remi

2013-09-01

The do-it-yourself biology (DIYbio) community is emerging as a movement that fosters open access to resources permitting modern molecular biology, and synthetic biology among others. It promises in particular to be a source of cheaper and simpler solutions for environmental monitoring, personal diagnostic and the use of biomaterials. The successful growth of a global community of DIYbio practitioners will depend largely on enabling safe access to state-of-the-art molecular biology tools and resources. In this paper we analyze the rise of DIYbio, its community, its material resources and its applications. We look at the current projects developed for the international genetically engineered machine competition in order to get a sense of what amateur biologists can potentially create in their community laboratories over the coming years. We also show why and how the DIYbio community, in the context of a global governance development, is putting in place a safety/ethical framework for guarantying the pursuit of its activity. And finally we argue that the global spread of DIY biology potentially reconfigures and opens up access to biological information and laboratory equipment and that, therefore, it can foster new practices and transversal collaborations between professional scientists and amateurs.

Can individual and social patterns of resource use buffer animal populations against resource decline?

Directory of Open Access Journals (Sweden)

Sam C Banks

Full Text Available Species in many ecosystems are facing declines of key resources. If we are to understand and predict the effects of resource loss on natural populations, we need to understand whether and how the way animals use resources changes under resource decline. We investigated how the abundance of arboreal marsupials varies in response to a critical resource, hollow-bearing trees. Principally, we asked what mechanisms mediate the relationship between resources and abundance? Do animals use a greater or smaller proportion of the remaining resource, and is there a change in cooperative resource use (den sharing, as the availability of hollow trees declines? Analyses of data from 160 sites surveyed from 1997 to 2007 showed that hollow tree availability was positively associated with abundance of the mountain brushtail possum, the agile antechinus and the greater glider. The abundance of Leadbeater's possum was primarily influenced by forest age. Notably, the relationship between abundance and hollow tree availability was significantly less than 1:1 for all species. This was due primarily to a significant increase by all species in the proportional use of hollow-bearing trees where the abundance of this resource was low. The resource-sharing response was weaker and inconsistent among species. Two species, the mountain brushtail possum and the agile antechinus, showed significant but contrasting relationships between the number of animals per occupied tree and hollow tree abundance. The discrepancies between the species can be explained partly by differences in several aspects of the species' biology, including body size, types of hollows used and social behaviour as it relates to hollow use. Our results show that individual and social aspects of resource use are not always static in response to resource availability and support the need to account for dynamic resource use patterns in predictive models of animal distribution and abundance.

Important features of Sustainable Aggregate Resource Management

Science.gov (United States)

Solar, Slavko V.; Shields, Deborah J.; Langer, William H.

2004-01-01

Every society, whether developed, developing or in a phase of renewal following governmental change, requires stable, adequate and secure supplies of natural resources. In the latter case, there could be significant need for construction materials for rebuilding infrastructure, industrial capacity, and housing. It is essential that these large-volume materials be provided in a rational manner that maximizes their societal contribution and minimizes environmental impacts. We describe an approach to resource management based on the principles of sustainable developed. Sustainable Aggregate Resource Management offers a way of addressing the conflicting needs and interests of environmental, economic, and social systems. Sustainability is an ethics based concept that utilizes science and democratic processes to reach acceptable agreements and tradeoffs among interests, while acknowledging the fundamental importance of the environment and social goods. We discuss the features of sustainable aggregate resource management.

Important Features of Sustainable Aggregate Resource Management

Directory of Open Access Journals (Sweden)

Slavko V. Šolar

2004-06-01

Full Text Available Every society, whether developed, developing or in a phase of renewal following governmental change, requires stable, adequate and secure supplies of natural resources. In the latter case, there could be significant need for construction materials for rebuilding infrastructure, industrial capacity, and housing. It is essential that these large-volume materials be provided in a rational manner that maximizes their societal contribution and minimizes environmental impacts. We describe an approach to resource management based on the principles of sustainable development. Sustainable Aggregate Resource Management offers a way of addressing the conflicting needs and interests of environmental, economic, and social systems. Sustainability is an ethics based concept that utilizes science and democratic processes to reach acceptable agreements and tradeoffs among interests, while acknowledging the fundamental importance of the environment and social goods. We discuss the features of sustainable aggregate resource management.

A semantic web ontology for small molecules and their biological targets.

Science.gov (United States)

Choi, Jooyoung; Davis, Melissa J; Newman, Andrew F; Ragan, Mark A

2010-05-24

A wide range of data on sequences, structures, pathways, and networks of genes and gene products is available for hypothesis testing and discovery in biological and biomedical research. However, data describing the physical, chemical, and biological properties of small molecules have not been well-integrated with these resources. Semantically rich representations of chemical data, combined with Semantic Web technologies, have the potential to enable the integration of small molecule and biomolecular data resources, expanding the scope and power of biomedical and pharmacological research. We employed the Semantic Web technologies Resource Description Framework (RDF) and Web Ontology Language (OWL) to generate a Small Molecule Ontology (SMO) that represents concepts and provides unique identifiers for biologically relevant properties of small molecules and their interactions with biomolecules, such as proteins. We instanced SMO using data from three public data sources, i.e., DrugBank, PubChem and UniProt, and converted to RDF triples. Evaluation of SMO by use of predetermined competency questions implemented as SPARQL queries demonstrated that data from chemical and biomolecular data sources were effectively represented and that useful knowledge can be extracted. These results illustrate the potential of Semantic Web technologies in chemical, biological, and pharmacological research and in drug discovery.

Programa Estrategico do desenvolvimento 1968-70: Area Estrategica IX. Infra-estructura Social. Educacao e Recursos Humanos, 1 e 2 (Strategic Development Program 1968-1970: Strategic Area IX. Education and Human Resources, Volumes 1 & 2).

Science.gov (United States)

Brazil.

This document is an English-language abstract (approximately 1,500 words) of a two volume work dealing with education and human resources as part of the Brazilian Government's Strategic Development Program 1968-70. It offers an integral view of education as an instrument of social transformation and an exposition of the quantitative and…

DOE EPSCoR Initiative in Structural and computational Biology/Bioinformatics

Energy Technology Data Exchange (ETDEWEB)

Wallace, Susan S.

2008-02-21

The overall goal of the DOE EPSCoR Initiative in Structural and Computational Biology was to enhance the competiveness of Vermont research in these scientific areas. To develop self-sustaining infrastructure, we increased the critical mass of faculty, developed shared resources that made junior researchers more competitive for federal research grants, implemented programs to train graduate and undergraduate students who participated in these research areas and provided seed money for research projects. During the time period funded by this DOE initiative: (1) four new faculty were recruited to the University of Vermont using DOE resources, three in Computational Biology and one in Structural Biology; (2) technical support was provided for the Computational and Structural Biology facilities; (3) twenty-two graduate students were directly funded by fellowships; (4) fifteen undergraduate students were supported during the summer; and (5) twenty-eight pilot projects were supported. Taken together these dollars resulted in a plethora of published papers, many in high profile journals in the fields and directly impacted competitive extramural funding based on structural or computational biology resulting in 49 million dollars awarded in grants (Appendix I), a 600% return on investment by DOE, the State and University.

Permanent foresty plots: a potentially valuable teaching resource in undergraduate biology porgrams for the Caribbean

Science.gov (United States)

H. Valles; C.M.S. Carrington

2016-01-01

There has been a recent proposal to change the way that biology is taught and learned in undergraduate biology programs in the USA so that students develop a better understanding of science and the natural world. Here, we use this new, recommended teaching– learning framework to assert that permanent forestry plots could be a valuable tool to help develop biology...

Impact of Climate Change on Water Resources in Taiwan

Directory of Open Access Journals (Sweden)

An-Yuan Tsai Wen-Cheng Huang

2011-01-01

Full Text Available This paper establishes a comprehensive assessment model to measure the regional impact of climate change on Taiwan¡¦s water resources. Working from future rainfall data simulated by Japan¡¦s high-resolution GCM model JMA/MRI TL959L60 in a SRES-A1B scenario, we first apply climate change to an assessment model of renewable water resources to estimate the volume of renewable water resources on a regional basis. We then conduct a water resources system simulation based on estimates of future water needs, regional reservoir effective capacity and renewable water resource volume. This paper uses three water resource assessment indicators: the annual water utilization ratio indicator, the water shortage indicator and the extreme event occurrence indicator. Through fuzzy comprehensive assessment, we divide the evaluation set into five levels: very good (L1, good (L2, fair (L3, poor (L4 and very poor (L5. Results indicate that, given the effects of future climate change (2080 - 2099 and the increase in water demand, future water resources conditions in northern and eastern Taiwan will not be significantly different from historical levels (1979 - 1998 and will maintain a ¡§good¡¨ level (L2, while the conditions in southern Taiwan will visibly deteriorate from its historical ¡§fair¡¨ level (L3 to ¡§poor¡¨ (L4; and the future conditions for central Taiwan will be ¡§poor¡¨ (L4. The initiation of adaptation options for water management in southern and central Taiwan would be needed by increasing reservoir capacity and reducing overall water use.

SIFTS: Structure Integration with Function, Taxonomy and Sequences resource

Science.gov (United States)

Velankar, Sameer; Dana, José M.; Jacobsen, Julius; van Ginkel, Glen; Gane, Paul J.; Luo, Jie; Oldfield, Thomas J.; O’Donovan, Claire; Martin, Maria-Jesus; Kleywegt, Gerard J.

2013-01-01

The Structure Integration with Function, Taxonomy and Sequences resource (SIFTS; http://pdbe.org/sifts) is a close collaboration between the Protein Data Bank in Europe (PDBe) and UniProt. The two teams have developed a semi-automated process for maintaining up-to-date cross-reference information to UniProt entries, for all protein chains in the PDB entries present in the UniProt database. This process is carried out for every weekly PDB release and the information is stored in the SIFTS database. The SIFTS process includes cross-references to other biological resources such as Pfam, SCOP, CATH, GO, InterPro and the NCBI taxonomy database. The information is exported in XML format, one file for each PDB entry, and is made available by FTP. Many bioinformatics resources use SIFTS data to obtain cross-references between the PDB and other biological databases so as to provide their users with up-to-date information. PMID:23203869

From waste management into resource management; Von der Entsorgungswirtschaft zur Ressourcenwirtschaft

Energy Technology Data Exchange (ETDEWEB)

Fricke, K.; Bergs, C.G.; Kosak, G.; Wallmann, R.; Vogtmann, H. (eds.)

2005-07-01

The main topic of the meeting was the development of waste management away from deposition management into resource management. The volume contains 63 contributions, which are compiled in several sections: legal and political development; status quo, concepts and prospects of thermal and mechanical waste treatment; sanitary landfills; outage associations; wastes and resources management; international waste management. (uke)

Liquid fuels from renewable resources in Canada: systems economics studies

National Research Council Canada - National Science Library

Osler, C. F

1978-01-01

This paper highlights the methodology and results of a six volume study completed for the Canadian government on alternatives for liquid fuel production from renewable resources after the mid-1980s...

OWL Reasoning Framework over Big Biological Knowledge Network

Science.gov (United States)

Chen, Huajun; Chen, Xi; Gu, Peiqin; Wu, Zhaohui; Yu, Tong

2014-01-01

Recently, huge amounts of data are generated in the domain of biology. Embedded with domain knowledge from different disciplines, the isolated biological resources are implicitly connected. Thus it has shaped a big network of versatile biological knowledge. Faced with such massive, disparate, and interlinked biological data, providing an efficient way to model, integrate, and analyze the big biological network becomes a challenge. In this paper, we present a general OWL (web ontology language) reasoning framework to study the implicit relationships among biological entities. A comprehensive biological ontology across traditional Chinese medicine (TCM) and western medicine (WM) is used to create a conceptual model for the biological network. Then corresponding biological data is integrated into a biological knowledge network as the data model. Based on the conceptual model and data model, a scalable OWL reasoning method is utilized to infer the potential associations between biological entities from the biological network. In our experiment, we focus on the association discovery between TCM and WM. The derived associations are quite useful for biologists to promote the development of novel drugs and TCM modernization. The experimental results show that the system achieves high efficiency, accuracy, scalability, and effectivity. PMID:24877076

The Virtual Institute for Integrative Biology (VIIB)

International Nuclear Information System (INIS)

Rivera, G.; Gonzalez-Nieto, F.; Perez-Acle, T.; Isea, R.; Holmes, D. S.

2007-01-01

The Virtual Institute for Integrative Biology (VII B) is a Latin American initiative for achieving global collaborative e-Science in the areas of bioinformatics, genome biology, systems biology, Metagenomic, medical applications and nanobiotechnolgy. The scientific agenda of VIIB includes: construction of databases for comparative genomic, the AlterORF database for alternate open reading frames discovery in genomes, bioinformatics services and protein simulations for biotechnological and medical applications. Human resource development has been promoted through co-sponsored students and shared teaching and seminars via video conferencing. E-Science challenges include: inter operability and connectivity concerns, high performance computing limitations, and the development of customized computational frameworks and flexible work flows to efficiently exploit shared resources without causing impediments to the user. Outreach programs include training workshops and classes for high school teachers and students and the new Adopt-a-Gene initiative. The VIIB has proved an effective way for small teams to transcend the critical mass problem, to overcome geographic limitations, to harness the power of large scale, collaborative science and improve the visibility of Latin American science It may provide a useful paradigm for developing further e-Science initiatives in Latin America and other emerging regions. (Author)

Water footprint as a tool for integrated water resources management

Science.gov (United States)

Aldaya, Maite; Hoekstra, Arjen

2010-05-01

In a context where water resources are unevenly distributed and, in some regions precipitation and drought conditions are increasing, enhanced water management is a major challenge to final consumers, businesses, water resource users, water managers and policymakers in general. By linking a large range of sectors and issues, virtual water trade and water footprint analyses provide an appropriate framework to find potential solutions and contribute to a better management of water resources. The water footprint is an indicator of freshwater use that looks not only at direct water use of a consumer or producer, but also at the indirect water use. The water footprint of a product is the volume of freshwater used to produce the product, measured over the full supply chain. It is a multi-dimensional indicator, showing water consumption volumes by source and polluted volumes by type of pollution; all components of a total water footprint are specified geographically and temporally. The water footprint breaks down into three components: the blue (volume of freshwater evaporated from surface or groundwater systems), green (water volume evaporated from rainwater stored in the soil as soil moisture) and grey water footprint (the volume of polluted water associated with the production of goods and services). Closely linked to the concept of water footprint is that of virtual water trade, which represents the amount of water embedded in traded products. Many nations save domestic water resources by importing water-intensive products and exporting commodities that are less water intensive. National water saving through the import of a product can imply saving water at a global level if the flow is from sites with high to sites with low water productivity. Virtual water trade between nations and even continents could thus be used as an instrument to improve global water use efficiency and to achieve water security in water-poor regions of the world. The virtual water trade

OECD Policy Recommendations on Security for Biological Materials

International Nuclear Information System (INIS)

Radisch, J.

2007-01-01

Biomedical innovations derived from research on pathogenic micro-organisms promise astounding health and economic benefits. Some such biological resources employed in the RandD for diagnostic kits, vaccines and therapeutics, however, possess capacity for dual-use; they may be misused to develop biological weapons. Research facilities entrusted with possession of such dual-use materials have a responsibility to comply with biosecurity measures that are designed to prevent loss or theft and thereby reduce the probability of a bioterrorist attack. The OECD has provided a forum for its Member countries to engage in a dialogue of international co-operation with a view to produce policies that achieve a research environment fortified by biosecurity measures and capable of producing health innovations. In 2007, the OECD developed a risk assessment framework and risk management principles for Biological Resource Centres. Ongoing policy work at the OECD will look to design biosecurity guidelines appropriate to a broader range of facilities in possession of dual-use materials, such as university and industrial laboratories.(author)

Stochastic chemical kinetics theory and (mostly) systems biological applications

CERN Document Server

Érdi, Péter; Lente, Gabor

2014-01-01

This volume reviews the theory and simulation methods of stochastic kinetics by integrating historical and recent perspectives, presents applications, mostly in the context of systems biology and also in combustion theory. In recent years, due to the development in experimental techniques, such as optical imaging, single cell analysis, and fluorescence spectroscopy, biochemical kinetic data inside single living cells have increasingly been available. The emergence of systems biology brought renaissance in the application of stochastic kinetic methods.

Application for approval of the Cold Lake Expansion Project: volume 2: environmental impact assessment: Part 1: biophysical and resource use assessment. Part 2: impact model descriptions

International Nuclear Information System (INIS)

Green, J.; Eccles, R.; Hegmann, G.; Morrison, L.; Salter, R.; van Egmond, T.; Vonk, P.; Ash, G.; Crowther, R.; Dance, T.; Edwards, W.; Veldman, W.

1997-02-01

An environmental assessment of the Cold Lake Expansion Project has been conducted to identify major issues of concern by public and government agencies, to determine means to eliminate or reduce those impacts, and to recommend any further efforts required to obtain missing information or monitor impacts. Volume 2 of the environmental impact assessment is divided into two parts. Part 1 (biophysical and resource use assessment) constitutes the primary environmental impact assessment document for the Cold Lake expansion project. It includes technical support documentation in regard to: (1) an assessment of noise impacts, (2) an assessment of greenhouse gas emissions, (3) a conceptual conservation and reclamation plan, (4) a historical resource impact assessment, and (5) a description of effects of oil spills on fish. Part 2 (impact model description) serves a reference document for part 1. It describes the approach taken in developing and assessing the impact models, discusses proposed methods for mitigation and management of residual impacts, and the recommended monitoring requirements for each of the major resource disciplines. The impact models describe the specific pathways through which impacts will occur as a result of interactions between project-related activities and important environmental components. 476 refs., 58 tabs., 23 figs

Mining influence on underground water resources in arid and semiarid regions

Science.gov (United States)

Luo, A. K.; Hou, Y.; Hu, X. Y.

2018-02-01

Coordinated mining of coal and water resources in arid and semiarid regions has traditionally become a focus issue. The research takes Energy and Chemical Base in Northern Shaanxi as an example, and conducts statistical analysis on coal yield and drainage volume from several large-scale mines in the mining area. Meanwhile, research determines average water volume per ton coal, and calculates four typical years’ drainage volume in different mining intensity. Then during mining drainage, with the combination of precipitation observation data in recent two decades and water level data from observation well, the calculation of groundwater table, precipitation infiltration recharge, and evaporation capacity are performed. Moreover, the research analyzes the transforming relationship between surface water, mine water, and groundwater. The result shows that the main reason for reduction of water resources quantity and transforming relationship between surface water, groundwater, and mine water is massive mine drainage, which is caused by large-scale coal mining in the research area.

Synthetic liquid fuels development: assessment of critical factors. Volume III. Coal resource depletion

Energy Technology Data Exchange (ETDEWEB)

Dickson, E.M.; Yabroff, I.W.; Kroll, C.A.; White, R.K.; Walton, B.L.; Ivory, M.E.; Fullen, R.E.; Weisbecker, L.W.; Hays, R.L.

1977-01-01

While US coal resources are known to be vast, their rate of depletion in a future based predominantly on coal has not been examined analytically heretofore. The Coal Depletion Model inventories the coal resource on a regional basis and calculates the cost of coal extraction by three technologies - strip and underground mining and in-situ combustion. A plausible coal demand scenario extending from 1975 to the year 2050 is used as a basis in applying the model. In the year 2050, plants in operation include 285 syncrude plants, each producing 100,000 B/D; 312 SNG plants, each producing 250 million SCF/D and 722 coal-fired electric power plants, each of 1000 MW capacity. In addition, there is 890 million tons per year of industrial coal consumption. Such a high level of coal use would deplete US coal resources much more rapidly than most people appreciate. Of course, the actual amount of US coal is unknown, and if the coal in the hypothetical reliability category is included, depletion is delayed. Coal in this category, however, has not been mapped; it is only presumed to exist on the basis of geological theory. The coal resource depletion model shows that unilateral imposition of a severance tax by a state tends to shift production to other coal producing regions. Boom and bust cycles are both delayed and reduced in their magnitude. When several states simultaneously impose severance taxes, the effect of each is weakened.Key policy issues that emerge from this analysis concern the need to reduce the uncertainty of the magnitude and geographic distribution of the US coal resource and the need to stimulate interaction among the parties at interest to work out equitable and acceptable coal conversion plant location strategies capable of coping with the challenges of a high-coal future.

The Protein Data Bank archive as an open data resource

Science.gov (United States)

Berman, Helen M.; Kleywegt, Gerard J.; Nakamura, Haruki; Markley, John L.

2014-10-01

The Protein Data Bank archive was established in 1971, and recently celebrated its 40th anniversary (Berman et al. in Structure 20:391, 2012). An analysis of interrelationships of the science, technology and community leads to further insights into how this resource evolved into one of the oldest and most widely used open-access data resources in biology.

The analysis of subsidence associated with geothermal development. Volume 1. Handbook

Energy Technology Data Exchange (ETDEWEB)

Atherton, R.W.; Finnemore, E.J.; Gillam, M.L.

1976-09-01

This study evaluates the state of knowledge of subsidence associated with geothermal development, and provides preliminary methods to assess the potential of land subsidence for any specific geothermal site. The results of this study are presented in three volumes. Volume 1 is designed to serve as a concise reference, a handbook, for the evaluation of the potential for land subsidence from the development of geothermal resources.

THE ECONOMETRICS OF THE FORECASTING OF FINANCIAL RESOURCES, A MAIN COMPONENT OF THE FINANCIAL MANAGEMENT

Directory of Open Access Journals (Sweden)

2009-05-01

Full Text Available The paper intends to emphasise the importance of budget resources forecasting for long periods of time, within thefinancial management. An as accurate as possible forecasting of the volume of financial resources will represent the basis forthe future projections of the expenditure of local communities, as they are regulated by law, knowing that one of the principlesrepresenting the basis of budget making is that of the balanced budget. To the same extent, the volume of the budget liquiditieswill depend on the rigorousness of the design of the volume of financial resources.. Beyond the abstract character of themathematic calculus made by specialists in econometrics, the financial manager is also interested to know the forecastingtechniques so that he/she can draw up the income and expenditure budget, the basis for the implementation of the economicsocialdevelopment strategies of the local communities. The financial management remains a fundamental component of thepublic management through the theoretical-methodological arsenal made available for the loan officer.

The integral biologically effective dose to predict brain stem toxicity of hypofractionated stereotactic radiotherapy

International Nuclear Information System (INIS)

Clark, Brenda G.; Souhami, Luis; Pla, Conrado; Al-Amro, Abdullah S.; Bahary, Jean-Paul; Villemure, Jean-Guy; Caron, Jean-Louis; Olivier, Andre; Podgorsak, Ervin B.

1998-01-01

Purpose: The aim of this work was to develop a parameter for use during fractionated stereotactic radiotherapy treatment planning to aid in the determination of the appropriate treatment volume and fractionation regimen that will minimize risk of late damage to normal tissue. Materials and Methods: We have used the linear quadratic model to assess the biologically effective dose at the periphery of stereotactic radiotherapy treatment volumes that impinge on the brain stem. This paper reports a retrospective study of 77 patients with malignant and benign intracranial lesions, treated between 1987 and 1995, with the dynamic rotation technique in 6 fractions over a period of 2 weeks, to a total dose of 42 Gy prescribed at the 90% isodose surface. From differential dose-volume histograms, we evaluated biologically effective dose-volume histograms and obtained an integral biologically-effective dose (IBED) in each case. Results: Of the 77 patients in the study, 36 had target volumes positioned so that the brain stem received more than 1% of the prescribed dose, and 4 of these, all treated for meningioma, developed serious late damage involving the brain stem. Other than type of lesion, the only significant variable was the volume of brain stem exposed. An analysis of the IBEDs received by these 36 patients shows evidence of a threshold value for late damage to the brain stem consistent with similar thresholds that have been determined for external beam radiotherapy. Conclusions: We have introduced a new parameter, the IBED, that may be used to represent the fractional effective dose to structures such as the brain stem that are partially irradiated with stereotactic dose distributions. The IBED is easily calculated prior to treatment and may be used to determine appropriate treatment volumes and fractionation regimens minimizing possible toxicity to normal tissue

Biological hydrogen formation by thermophilic bacteria

NARCIS (Netherlands)

Bielen, A.A.M.

2014-01-01

Hydrogen gas (H₂) is an important chemical commodity. It is used in many industrial processes and is applicable as a fuel. However, present production processes are predominantly based on non-renewable resources. In a biological H₂ (bioH₂) production

Modeling of response, socioeconomic, and natural resource damage costs for hypothetical oil spill scenarios in San Francisco Bay

International Nuclear Information System (INIS)

Etkin, D.S.; French McCay, D.; Whittier, N.; Sankaranarayanan, S.; Jennings, J.

2002-01-01

A study was conducted to determine the influence of oil type, spill size, response strategy and location factors on oil spill response costs, with particular reference to the cost benefits of the use of dispersants. Modeling has been conducted for a hypothetical oil spill in San Francisco Bay to determine biological impacts, damages to natural resources and response costs. The SIMAP modeling software by the Applied Science Associates was used to model 3 spill sizes (20, 50 and 95 percentile by volume) and 4 types of oil (gasoline, diesel, heavy fuel oil, and crude oil). Response costs, natural resource damages and socioeconomic impact were determined based on spill trajectory and fate. Mechanical recovery-based operations carry higher response costs than dispersant-based operations. Response costs for diesel and gasoline spills make up 20 per cent of the total costs, compared to 43 per cent for crude and heavy fuel oil spills. Damages to natural resources are higher for spills of toxic lighter fuels such as gasoline and diesel because gasoline has a greater impact on the water column with less shoreline oiling, resulting in more damages to natural resources. Heavier oils have a greater impact on shorelines and higher response and socioeconomic costs. Although socioeconomic costs varied by location, they tend to be greater than response costs and natural resource damage costs. Proportions of the different costs were described with reference to various spill factors. Socioeconomic costs are 61, 76, 45 and 53 per cent respectively for gasoline, diesel, crude oil, and heavy fuel oil spills. 27 refs., 23 tabs., 5 figs

Biological effects data: Fluoride and sulfur dioxide

Energy Technology Data Exchange (ETDEWEB)

McMechan, K.J. (ed.); Holton, R.L.; Ulbricht, R.J.; Morgan , J.B.

1975-04-01

The Alumax Pacific Aluminum Corporation has proposed construction of an aluminum reduction facility near Youngs Bay at Warrenton, Oregon. This report comprises one part of the final report to Alumax on a research project entitled, Physical, Chemical and Biological Studies of Youngs Bay.'' It presents data pertaining to the potential biological effects of fluoride and sulfur dioxide, two potentially hazardous plant-stack emissions, on selected aquatic species of the area. Companion volumes provide a description of the physical characteristics the geochemistry, and the aquatic animals present in Youngs Bay and adjacent ecosystems. An introductory volume provides general information and maps of the area, and summarizes the conclusions of all four studies. The data from the two phases of the experimental program are included in this report: lethal studies on the effects of selected levels of fluoride and sulfur dioxide on the survival rate of eleven Youngs Bay faunal species from four phyla, and sublethal studies on the effects of fluoride and sulfur dioxide on the rate of primary production of phytoplankton. 44 refs., 18 figs., 38 tabs.

Complexity, Analysis and Control of Singular Biological Systems

CERN Document Server

Zhang, Qingling; Zhang, Xue

2012-01-01

Complexity, Analysis and Control of Singular Biological Systems follows the control of real-world biological systems at both ecological and phyisological levels concentrating on the application of now-extensively-investigated singular system theory. Much effort has recently been dedicated to the modelling and analysis of developing bioeconomic systems and the text establishes singular examples of these, showing how proper control can help to maintain sustainable economic development of biological resources. The book begins from the essentials of singular systems theory and bifurcations before tackling  the use of various forms of control in singular biological systems using examples including predator-prey relationships and viral vaccination and quarantine control. Researchers and graduate students studying the control of complex biological systems are shown how a variety of methods can be brought to bear and practitioners working with the economics of biological systems and their control will also find the ...

Resources and Operations Section

International Nuclear Information System (INIS)

Burgess, R.L.

1978-01-01

Progress is reported on the data resources group with regard to numeric information support; IBP data center; and geoecology project. Systems ecology studies consisted of nonlinear analysis-time delays in a host-parasite model; dispersal of seeds by animals; three-dimensional computer graphics in ecology; spatial heterogeneity in ecosystems; and analysis of forest structure. Progress is also reported on the national inventory of biological monitoring programs; ecological sciences information center; and educational activities

Moderator's view: High-volume plasma exchange: pro, con and consensus.

Science.gov (United States)

Kaplan, Andre A

2017-09-01

I have been asked to comment on the pro and con opinions regarding high-volume plasma exchange. The authors of both positions have provided cogent arguments and a reasonable approach to choosing the exchange volume for any given therapeutic plasma exchange. The major issue of relevance in this discussion is the nature of the toxins targeted for removal. These parameters include molecular weight, the apparent volume of distribution, the degree of protein binding, the biologic and chemical half-life, and the severity and rapidity of its toxicity. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Climate change and water resources

International Nuclear Information System (INIS)

Younos, Tamim; Grady, Caitlin A.

2013-01-01

This volume presents nine chapters prepared by international authors and highlighting various aspects of climate change and water resources. Climate change models and scenarios, particularly those related to precipitation projection, are discussed and uncertainties and data deficiencies that affect the reliability of predictions are identified. The potential impacts of climate change on water resources (including quality) and on crop production are analyzed and adaptation strategies for crop production are offered. Furthermore, case studies of climate change mitigation strategies, such as the reduction of water use and conservation measures in urban environments, are included. This book will serve as a valuable reference work for researchers and students in water and environmental sciences, as well as for governmental agencies and policy makers.

Climate change and water resources

Energy Technology Data Exchange (ETDEWEB)

Younos, Tamim [The Cabell Brand Center for Global Poverty and Resource Sustainability Studies, Salem, VA (United States); Grady, Caitlin A. (ed.) [Purdue Univ., West Lafayette, IN (United States). Ecological Sciences and Engineering Program

2013-07-01

This volume presents nine chapters prepared by international authors and highlighting various aspects of climate change and water resources. Climate change models and scenarios, particularly those related to precipitation projection, are discussed and uncertainties and data deficiencies that affect the reliability of predictions are identified. The potential impacts of climate change on water resources (including quality) and on crop production are analyzed and adaptation strategies for crop production are offered. Furthermore, case studies of climate change mitigation strategies, such as the reduction of water use and conservation measures in urban environments, are included. This book will serve as a valuable reference work for researchers and students in water and environmental sciences, as well as for governmental agencies and policy makers.

Conservation businesses and conservation planning in a biological diversity hotspot.

Science.gov (United States)

Di Minin, Enrico; Macmillan, Douglas Craig; Goodman, Peter Styan; Escott, Boyd; Slotow, Rob; Moilanen, Atte

2013-08-01

The allocation of land to biological diversity conservation competes with other land uses and the needs of society for development, food, and extraction of natural resources. Trade-offs between biological diversity conservation and alternative land uses are unavoidable, given the realities of limited conservation resources and the competing demands of society. We developed a conservation-planning assessment for the South African province of KwaZulu-Natal, which forms the central component of the Maputaland-Pondoland-Albany biological diversity hotspot. Our objective was to enhance biological diversity protection while promoting sustainable development and providing spatial guidance in the resolution of potential policy conflicts over priority areas for conservation at risk of transformation. The conservation-planning assessment combined spatial-distribution models for 646 conservation features, spatial economic-return models for 28 alternative land uses, and spatial maps for 4 threats. Nature-based tourism businesses were competitive with other land uses and could provide revenues of >US$60 million/year to local stakeholders and simultaneously help meeting conservation goals for almost half the conservation features in the planning region. Accounting for opportunity costs substantially decreased conflicts between biological diversity, agricultural use, commercial forestry, and mining. Accounting for economic benefits arising from conservation and reducing potential policy conflicts with alternative plans for development can provide opportunities for successful strategies that combine conservation and sustainable development and facilitate conservation action. © 2013 Society for Conservation Biology.

Management Strategy for Hydroelectric Project Toro 2: Knowing and enhancing natural resources sustainably

Directory of Open Access Journals (Sweden)

José Pereira Chaves

2014-01-01

Full Text Available The aim of this article is to understand and sustainably enhance the biological and ecological resources of the Hydroelectric Project of Toro 2, thus; a research was carried out to inventory the presence of birds, mammals and plants, in order to know if the site qualifies as a biological tourist attraction, as well as to know the opinion of local people. It is proposed the sustainable uses of natural resources, through a strategy of use, management and conservation of the ecosystems.

Nanotechnology, resources, and pollution control

Science.gov (United States)

Gillett, Stephen L.

1996-09-01

The separation of different kinds of atoms or molecules from each other is a fundamental technological problem. Current techniques of resource extraction, which use the ancient paradigm of the differential partitioning of elements into coexisting phases, are simple but extremely wasteful and require feedstocks (`ores') that are already anomalously enriched. This is impractical for pollution control and desalination, which require extraction of low concentrations; instead, atomistic separation, typically by differential motion through semipermeable membranes, is used. The present application of such membranes is seriously limited, however, mostly because of limitations in their fabrication by conventional bulk techniques. The capabilities of biological systems, such as vertebrate kidneys, are vastly better, largely because they are intrinsically structured at a molecular scale. Nanofabrication of semipermeable membranes promises capabilities on the order of those of biological systems, and this in turn could provide much financial incentive for the development of molecular assemblers, as well established markets exist already. Continued incentives would exist, moreover, as markets expanded with decreasing costs, leading to such further applications as remediation of polluted sites, cheap desalination, and resource extraction from very low-grade sources.

Economic development and conservation of biological and cultural diversity in Yunnan Province, China

Science.gov (United States)

Stendell, R.C.; Johnson, Richard L.; Mosesso, J.P.; Zhang, X.

2001-01-01

Chinese and American scientists are co-operating to develop concepts, strategies, agreements, and proposals in support of an economic development and sustainable ecosystems project in Yunnan Province, People's Republic of China. Yunnan's Provincial Government has initiated a major programme to develop and further utilise its biological resources to help improve economic conditions for its citizens. They are co-operating with the US Geological Survey (USGS) on evaluation and management of biological resources so economic development will be compatible with sustainable ecological systems. Scientists from the USGS and co-operating universities will provide expertise on synthesising biological data, conducting a Gap Analysis for the Province, evaluating innovative economic opportunities, and designing an effective education, training, and outreach programme.

Exploiting Growing Stock Volume Maps for Large Scale Forest Resource Assessment: Cross-Comparisons of ASAR- and PALSAR-Based GSV Estimates with Forest Inventory in Central Siberia

Directory of Open Access Journals (Sweden)

Christian Hüttich

2014-07-01

Full Text Available Growing stock volume is an important biophysical parameter describing the state and dynamics of the Boreal zone. Validation of growing stock volume (GSV maps based on satellite remote sensing is challenging due to the lack of consistent ground reference data. The monitoring and assessment of the remote Russian forest resources of Siberia can only be done by integrating remote sensing techniques and interdisciplinary collaboration. In this paper, we assess the information content of GSV estimates in Central Siberian forests obtained at 25 m from ALOS-PALSAR and 1 km from ENVISAT-ASAR backscatter data. The estimates have been cross-compared with respect to forest inventory data showing 34% relative RMSE for the ASAR-based GSV retrievals and 39.4% for the PALSAR-based estimates of GSV. Fragmentation analyses using a MODIS-based land cover dataset revealed an increase of retrieval error with increasing fragmentation of the landscape. Cross-comparisons of multiple SAR-based GSV estimates helped to detect inconsistencies in the forest inventory data and can support an update of outdated forest inventory stands.

Biology as a Study of Man and Society

Science.gov (United States)

Hurd, Paul DeHart

1971-01-01

Biology ought to be taught within the context of human culture; "man" can be the "type animal." Consideration should be given to questions of race, population, food resources, environmental quality, intelligence, genetic engineering, and organ transplants. (AL)

Information resources and the correlation of response patterns between biological end points

Energy Technology Data Exchange (ETDEWEB)

Malling, H.V. [National Institute of Environmental Health Sciences, Research Triangle Park, NC (United States); Wassom, J.S. [Oak Ridge National Laboratory, TN (United States)

1990-12-31

This paper focuses on the analysis of information for mutagenesis, a biological end point that is important in the overall process of assessing possible adverse health effects from chemical exposure. 17 refs.

Formation of organizational and economic mechanism of rational use of aquatic biological resources

Directory of Open Access Journals (Sweden)

Stolbov A. G.

2017-09-01

Full Text Available The state of fisheries has been researched based on a systematic approach and comprehensive analysis of statistical data, the following issues have been characterized: the catch of aquatic biological resources (ABR, consumption of fish products, problems in the development of the fishing industry (fleet aging, lack of innovative technologies, the proliferation of IUU fishing4 , the high level of retail prices for fish, low degree of processing export products, overshoot "improper objects" of fishing, the gap in aquaculture development, low economic efficiency. To improve the quality of fishery management it has been proposed to form the organizational and economic mechanism of ABR rational use, which should include effective tools for the implementation of management decisions. Instead of the so-called "historical" principle it has been suggested to use the investment principle of quota allocation and rental payments. The basis for management of fishing industry should be scientifically based on the bioeconomic concept of ABR rational use, the essence of which is to preserve the ABR and at the same time to obtain the maximum output of finished products with high added value. To form the organizational and economic mechanism it is necessary to develop a programme of innovative development of the fisheries sector, a calendar programme of upgrading of fishing fleet, wellreasoned differential rates of rent payments for the ABR use, scenarios and graphic organization of work of fishing vessels in specific fishing areas, to form regional financial and industrial clusters, to expand the authority of the Fisheries Agency, to improve corporate social responsibility of the fishing business communities. Modernization of management system for ABR rational use can significantly reduce environmental pollution, ensure the effective delivery of catch to shore, their high-quality processing and the needs of the population in fish products.

Energy-efficient buildings program evaluations. Volume 2: Evaluation summaries

Energy Technology Data Exchange (ETDEWEB)

Lee, A.D.; Mayi, D.; Edgemon, S.D.

1997-04-01

This document presents summaries of code and utility building program evaluations reviewed as the basis for the information presented in Energy-Efficient Buildings Program Evaluations, Volume 1: Findings and Recommendations, DOE/EE/OBT-11569, Vol. 1. The main purpose of this volume is to summarize information from prior evaluations of similar programs that may be useful background for designing and conducting an evaluation of the BSGP. Another purpose is to summarize an extensive set of relevant evaluations and provide a resource for program designers, mangers, and evaluators.

Property regime concerning genetic resources and traditional knowledge

Directory of Open Access Journals (Sweden)

Gabriel R. Nemogá Soto

2001-01-01

Full Text Available This article provides an historical account of the changes that have taken place regarding ownership, control and access over genetic resources. Once considered the common heritage of humanity, rights over genetic resources, it is argued, have undergone radical transformations. The global legal framework regarding genetic resources has shifted to legitimize and promote their appropriation and monopolization. This transformation embraced the expansion of intellectual property rights over genetic material and information, including living organisms, through the World Trade Organization´s Trade Related Aspects of Intellectual Property (TRIPs. This was coupled by the adoption of the United Nations Convention on Biological Diversity, which recognizes sovereign rights of the countries of origin over their genetic resources and, at the same time, obligates them to permit access to those resources. The Colombian Constitution of 1991 and unparalleled judicial decisions during the last decade reaffirmed sovereign rights over genetic resources in Colombia. Conversely, the genetic resources and the traditional knowledge of Indigenous peoples and local communities continue to be freely accessible resources within the current Colombian legal framework.

Don’t bust the biological soil crust: Preserving and restoring an important desert resource

Science.gov (United States)

Sue Miller; Steve Warren; Larry St. Clair

2017-01-01

Biological soil crusts are a complex of microscopic organisms growing on the soil surface in many arid and semi-arid ecosystems. These crusts perform the important role of stabilizing soil and reducing or eliminating water and wind erosion. One of the largest threats to biological soil crusts in the arid and semi-arid areas of the western United States is mechanical...

Evaluation of the effect of prostate volume change on tumor control probability in LDR brachytherapy.

Science.gov (United States)

Knaup, Courtney; Mavroidis, Panayiotis; Stathakis, Sotirios; Smith, Mark; Swanson, Gregory; Papanikolaou, Niko

2011-09-01

This study evaluates low dose-rate brachytherapy (LDR) prostate plans to determine the biological effect of dose degradation due to prostate volume changes. In this study, 39 patients were evaluated. Pre-implant prostate volume was determined using ultrasound. These images were used with the treatment planning system (Nucletron Spot Pro 3.1(®)) to create treatment plans using (103)Pd seeds. Following the implant, patients were imaged using CT for post-implant dosimetry. From the pre and post-implant DVHs, the biologically equivalent dose and the tumor control probability (TCP) were determined using the biologically effective uniform dose. The model used RBE = 1.75 and α/β = 2 Gy. The prostate volume changed between pre and post implant image sets ranged from -8% to 110%. TCP and the mean dose were reduced up to 21% and 56%, respectively. TCP is observed to decrease as the mean dose decreases to the prostate. The post-implant tumor dose was generally observed to decrease, compared to the planned dose. A critical uniform dose of 130 Gy was established. Below this dose, TCP begins to fall-off. It was also determined that patients with a small prostates were more likely to suffer TCP decrease. The biological effect of post operative prostate growth due to operative trauma in LDR was evaluated using the concept. The post-implant dose was lower than the planned dose due to an increase of prostate volume post-implant. A critical uniform dose of 130 Gy was determined, below which TCP begun to decline.

Approaches to monitoring biological outcomes for HPV vaccination: challenges of early adopter countries

DEFF Research Database (Denmark)

Wong, Charlene A; Saraiya, Mona; Hariri, Susan

2011-01-01

In this review, we describe plans to monitor the impact of human papillomavirus (HPV) vaccine on biologic outcomes in selected international areas (Australia, Canada, Mexico, the Nordic countries, Scotland, and the United States) that have adopted this vaccine. This summary of monitoring plans...... provides a background for discussing the challenges of vaccine monitoring in settings where resources and capacity may vary. A variety of approaches that depend on existing infrastructure and resources are planned or underway for monitoring HPV vaccine impact. Monitoring HPV vaccine impact on biologic...

30 CFR 402.6 - Water-Resources Research Program.

Science.gov (United States)

2010-07-01

... productivity of water when used for agricultural, municipal, and commercial purposes; and (8) The economic, legal, engineering, social, recreational, biological, geographic, ecological, and other aspects of water... interpreting the results of scientific and engineering research on water-resources problems. (10) Providing...

The timber resources of Rhode Island

Science.gov (United States)

Roland H. Ferguson; John R. McGuire; John R. McGuire

1957-01-01

This is a report on the first comprehensive survey ever made of the timber resources of Rhode Island. It shows, for the years 1952 and 1953, the area and condition of the forest land, the volume and quality of standing timber, the rates of timber growth and mortality, and the extent of timber cutting for forest products. The survey was made by the Forest Service as...

Recent development of computational resources for new antibiotics discovery

DEFF Research Database (Denmark)

Kim, Hyun Uk; Blin, Kai; Lee, Sang Yup

2017-01-01

Understanding a complex working mechanism of biosynthetic gene clusters (BGCs) encoding secondary metabolites is a key to discovery of new antibiotics. Computational resources continue to be developed in order to better process increasing volumes of genome and chemistry data, and thereby better...

Attractor neural networks with resource-efficient synaptic connectivity

Science.gov (United States)

Pehlevan, Cengiz; Sengupta, Anirvan

Memories are thought to be stored in the attractor states of recurrent neural networks. Here we explore how resource constraints interplay with memory storage function to shape synaptic connectivity of attractor networks. We propose that given a set of memories, in the form of population activity patterns, the neural circuit choses a synaptic connectivity configuration that minimizes a resource usage cost. We argue that the total synaptic weight (l1-norm) in the network measures the resource cost because synaptic weight is correlated with synaptic volume, which is a limited resource, and is proportional to neurotransmitter release and post-synaptic current, both of which cost energy. Using numerical simulations and replica theory, we characterize optimal connectivity profiles in resource-efficient attractor networks. Our theory explains several experimental observations on cortical connectivity profiles, 1) connectivity is sparse, because synapses are costly, 2) bidirectional connections are overrepresented and 3) are stronger, because attractor states need strong recurrence.

Equilibrium and Dynamic Osmotic Behaviour of Aqueous Solutions with Varied Concentration at Constant and Variable Volume

Science.gov (United States)

Minkov, Ivan L.; Manev, Emil D.; Sazdanova, Svetla V.; Kolikov, Kiril H.

2013-01-01

Osmosis is essential for the living organisms. In biological systems the process usually occurs in confined volumes and may express specific features. The osmotic pressure in aqueous solutions was studied here experimentally as a function of solute concentration (0.05–0.5 M) in two different regimes: of constant and variable solution volume. Sucrose, a biologically active substance, was chosen as a reference solute for the complex tests. A custom made osmotic cell was used. A novel operative experimental approach, employing limited variation of the solution volume, was developed and applied for the purpose. The established equilibrium values of the osmotic pressure are in agreement with the theoretical expectations and do not exhibit any evident differences for both regimes. In contrast, the obtained kinetic dependences reveal striking divergence in the rates of the process at constant and varied solution volume for the respective solute concentrations. The rise of pressure is much faster at constant solution volume, while the solvent influx is many times greater in the regime of variable volume. The results obtained suggest a feasible mechanism for the way in which the living cells rapidly achieve osmotic equilibrium upon changes in the environment. PMID:24459448

Making United States Integrated Ocean Observing System (U.S. IOOS) inclusive of marine biological resources

Science.gov (United States)

Moustahfid, H.; Potemra, J.; Goldstein, P.; Mendelssohn, R.; Desrochers, A.

2011-01-01

An important Data Management and Communication (DMAC) goal is to enable a multi-disciplinary view of the ocean environment by facilitating discovery and integration of data from various sources, projects and scientific domains. United States Integrated Ocean Observing System (U.S. IOOS) DMAC functional requirements are based upon guidelines for standardized data access services, data formats, metadata, controlled vocabularies, and other conventions. So far, the data integration effort has focused on geophysical U.S. IOOS core variables such as temperature, salinity, ocean currents, etc. The IOOS Biological Observations Project is addressing the DMAC requirements that pertain to biological observations standards and interoperability applicable to U.S. IOOS and to various observing systems. Biological observations are highly heterogeneous and the variety of formats, logical structures, and sampling methods create significant challenges. Here we describe an informatics framework for biological observing data (e.g. species presence/absence and abundance data) that will expand information content and reconcile standards for the representation and integration of these biological observations for users to maximize the value of these observing data. We further propose that the approach described can be applied to other datasets generated in scientific observing surveys and will provide a vehicle for wider dissemination of biological observing data. We propose to employ data definition conventions that are well understood in U.S. IOOS and to combine these with ratified terminologies, policies and guidelines. ?? 2011 MTS.

CeDAMar global database of abyssal biological sampling

OpenAIRE

Stuart, Carol T.; Arbizu, Pedro Martinez; Smith, Craig R.; Molodtsova, Tina; Brandt, Angelika; Etter, Ron J.; Escobar-briones, Elva; Fabri, Marie-claire; Rex, Michael A.

2008-01-01

The Census of the Diversity of Abyssal Marine Life (CeDAMar), a division of the Census of Marine Life, has compiled the first comprehensive global database of biological samples taken in the abyssal plains of the world ocean. It is an essential resource for planning future exploration of the abyss, for synthesizing patterns of biogeography and biodiversity, and for environmentally safe exploitation of natural resources. The database is described in this article, and made available to investig...

[Collections of human biological resources for research purposes: from regulations to the need of a guide of good collection practices].

Science.gov (United States)

Le Roux, N; de Montgolfier, S; di Donato, J-H; Boccon-Gibod, L; Teillac, P; Hervé, C; Berthon, P

2003-12-01

In France, collections of human biological resources are regulated by the "Bioethics Law", currently in revision. Hence, we analyse the regulatory and ethical issues of these practices in the context of scientific research. The ultimate aim of such collections is to improve biological and medical knowledge. We think that the French regulatory system is quite complicated and non-explicit for "collection holders". The multiplicity of legal texts concerning this activity has made their application difficult, especially in the absence of application decrees. The project amending the actual law has clarified the legal status of collections but it did not shed light on the status of human body detached parts. Furthermore, the text is still very far from the international bioethical recommendations, and does not reflect the actual collection's implementation. The establishment of a guideline of Good Collection Practices, based on clear principles, should help to simplify the situation, especially when it is imbedded in the regulation and linked to control procedures. It would allow a balance between collective interests and the protection of individuals, taking into account of the international highly competitive scientific and economical constraints. The major issue is to preserve and to perpetuate the existing and future collections because of their precious value as an important tool for biomedical knowledge. The efficiency of a regulation depends on its legibility and accessibility, two requirements that seem to determine the acceptance of the regulatory tool and its application allowing subsequently to reach fairness in proceedings.

Collaborative Posters Develop Students' Ability to Communicate about Undervalued Scientific Resources to Nonscientists.

Science.gov (United States)

Mayfield, Teresa J; Olimpo, Jeffrey T; Floyd, Kevin W; Greenbaum, Eli

2018-01-01

Scientists are increasingly called upon to communicate with the public, yet most never receive formal training in this area. Public understanding is particularly critical to maintaining support for undervalued resources such as biological collections, research data repositories, and expensive equipment. We describe activities carried out in an inquiry-driven organismal biology laboratory course designed to engage a diverse student body using biological collections. The goals of this cooperative learning experience were to increase students' ability to locate and comprehend primary research articles, and to communicate the importance of an undervalued scientific resource to nonscientists. Our results indicate that collaboratively created, research-focused informational posters are an effective tool for achieving these goals and may be applied in other disciplines or classroom settings.

Resource management plan for the Oak Ridge Reservation. Volume 27, Wildlife Management Plan

Energy Technology Data Exchange (ETDEWEB)

Parr, P.D. [Oak Ridge National Lab., TN (United States); Evans, J.W. [Tennessee Wildlife Resources Agency, Knoxville, TN (United States)

1992-06-01

A plan for management of the wildlife resources on the US Department of Energy`s Oak Ridge Reservation is outlined in this document. Management includes wildlife population control (hunts, trapping, and removal), handling specific problems with wildlife, restoration of species, coordination with researchers on wildlife studies, preservation and management of habitats, and law enforcement. Wildlife resources are divided into five categories, each with a specific set of objectives and procedures for obtaining these objectives. These categories are (1) species-richness management to ensure that all resident wildlife species exist on the Reservation in viable numbers; (2) featured species management to produce selected species in desired numbers on designated land units; (3) management of game species for research, education, recreation, and public safety, (4) endangered species management designed to preserve and protect both the species and habitats critical to the survival of those species; and (5) pest management. Achievement of the objectives is a joint effort between the Tennessee Wildlife Resources Agency and the Oak Ridge National Laboratory`s Environmental Sciences Division.

Effects of international football matches on ambulance call profiles and volumes during the 2006 World Cup.

Science.gov (United States)

Deakin, Charles D; Thompson, Fizz; Gibson, Caroline; Green, Mark

2007-06-01

Prompt ambulance attendance is aimed at improving patient care. With finite resources struggling to meet performance targets, unforeseen demand precludes the ability to tailor resources to cope with increased call volumes, and can have a marked detrimental effect on performance and hence patient care. The effects of the 2006 World Cup football matches on call volumes and profiles were analysed to understand how public events can influence demands on the ambulance service. All emergency calls to the Hampshire Ambulance Service NHS Trust (currently the Hampshire Division of South Central Ambulance Service, Winchester, UK) during the first weekend of the 2006 World Cup football matches were analysed by call volume and classification of call (call type). On the day of the first football match, call volume was over 50% higher than that on a typical Saturday, with distinct peaks before and after the inaugural match. Call profile analysis showed increases in alcohol-related emergencies, including collapse, unconsciousness, assault and road traffic accidents. The increase in assaults was particularly marked at the end of each match and increased again into the late evening. A detailed mapping of call volumes and profiles during the World Cup football shows a significant increase in overall emergency calls, mostly alcohol related. Mapping of limited resources to these patterns will allow improved responses to emergency calls.

Big Data in Plant Science: Resources and Data Mining Tools for Plant Genomics and Proteomics.

Science.gov (United States)

Popescu, George V; Noutsos, Christos; Popescu, Sorina C

2016-01-01

In modern plant biology, progress is increasingly defined by the scientists' ability to gather and analyze data sets of high volume and complexity, otherwise known as "big data". Arguably, the largest increase in the volume of plant data sets over the last decade is a consequence of the application of the next-generation sequencing and mass-spectrometry technologies to the study of experimental model and crop plants. The increase in quantity and complexity of biological data brings challenges, mostly associated with data acquisition, processing, and sharing within the scientific community. Nonetheless, big data in plant science create unique opportunities in advancing our understanding of complex biological processes at a level of accuracy without precedence, and establish a base for the plant systems biology. In this chapter, we summarize the major drivers of big data in plant science and big data initiatives in life sciences with a focus on the scope and impact of iPlant, a representative cyberinfrastructure platform for plant science.

Optimisation of biological reactors using the 'biological resonance' phenomenon; Ansatz zur Optimierung biologischer Reinigungsstufen durch das Phaenomen der ''Biologischen Resonanz''

Energy Technology Data Exchange (ETDEWEB)

Schmid, A.

2003-07-01

The microbial catabolic activity of biological reactors can be increased by up to 75% through external stimulation with intermittent stress loads at intervals of several minutes. Under these process conditions, the ''biological resonance'' phenomenon determines the system and leads to an increased synthesis of enzymes. In addition to computer simulations, experiments with activated sludge were carried out in a 10-litre bioreactor. By modulating the stress intervals, a permanent increase in catabolic activity of about 60% was achieved during these experiments. By relying on the ''biological resonance'' phenomenon, the required reaction volume of biological treatment units can probably be reduced by up to 40%. (orig.)

New Approaches in Cancer Biology Can Inform the Biology Curriculum.

Science.gov (United States)

Jones, Lynda; Gordon, Diana; Zelinski, Mary

2018-03-01

Students tend to be very interested in medical issues that affect them and their friends and family. Using cancer as a hook, the ART of Reproductive Medicine: Oncofertility curriculum (free, online, and NIH sponsored) has been developed to supplement the teaching of basic biological concepts and to connect biology and biomedical research. This approach allows integration of up-to-date information on cancer and cancer treatment, cell division, male and female reproductive anatomy and physiology, cryopreservation, fertility preservation, stem cells, ethics, and epigenetics into an existing biology curriculum. Many of the topics covered in the curriculum relate to other scientific disciplines, such as the latest developments in stem cell research including tissue bioengineering and gene therapy for inherited mitochondrial disease, how epigenetics occurs chemically to affect gene expression or suppression and how it can be passed down through the generations, and the variety of biomedical careers students could pursue. The labs are designed to be open-ended and inquiry-based, and extensions to the experiments are provided so that students can explore questions further. Case studies and ethical dilemmas are provided to encourage thoughtful discussion. In addition, each chapter of the curriculum includes links to scientific papers, additional resources on each topic, and NGSS alignment.

Effects of buffer ionization in protein transition volumes.

Science.gov (United States)

Lee, Soyoung; Heerklotz, Heiko; Chalikian, Tigran V

2010-05-01

Protein denaturation events are generally associated with a change in the state of ionization of abnormally titrating groups and, therefore, are coupled with changes in buffer ionization/neutralization equilibria. Consequently, buffer ionization should influence the measured change in volume accompanying protein denaturation. Changes in volume accompanying protein denaturation reflect the differential packing and hydration of polypeptide chains in their native and denatured conformations while also describing the pressure stability of proteins. A characteristic feature of conformational transitions of globular proteins is a near zero change in volume that is comparable in magnitude with the volume of ionization of biologically relevant buffers. Thus, the impact of buffer ionization on the volume of protein denaturation could be very significant with the potential to affect not only its magnitude but also its sign. To investigate this point quantitatively, we performed pressure perturbation calorimetric (PPC) studies of lysozyme and ribonuclease A at pH 3.0 in four buffers differing in their ionization volumes. Our results identify buffer ionization as an important determinant of protein transition volume that needs to be carefully taken into account. We emphasize that the importance of our results is not limited to PPC measurements but is more general and applies to all volumetric investigations, in particular, extending to the derivation of the pressure-temperature phase diagram of protein stability.

National Aeronautics and Space Administration Biological Specimen Repository

Science.gov (United States)

McMonigal, Kathleen A.; Pietrzyk, Robert a.; Johnson, Mary Anne

2008-01-01

The National Aeronautics and Space Administration Biological Specimen Repository (Repository) is a storage bank that is used to maintain biological specimens over extended periods of time and under well-controlled conditions. Samples from the International Space Station (ISS), including blood and urine, will be collected, processed and archived during the preflight, inflight and postflight phases of ISS missions. This investigation has been developed to archive biosamples for use as a resource for future space flight related research. The International Space Station (ISS) provides a platform to investigate the effects of microgravity on human physiology prior to lunar and exploration class missions. The storage of crewmember samples from many different ISS flights in a single repository will be a valuable resource with which researchers can study space flight related changes and investigate physiological markers. The development of the National Aeronautics and Space Administration Biological Specimen Repository will allow for the collection, processing, storage, maintenance, and ethical distribution of biosamples to meet goals of scientific and programmatic relevance to the space program. Archiving of the biosamples will provide future research opportunities including investigating patterns of physiological changes, analysis of components unknown at this time or analyses performed by new methodologies.

Do new Access and Benefit Sharing procedures under the Convention on Biological Diversity threaten the future of biological control? Supplemental material (case studies, natural enemy releases, country views concerning ABS)

NARCIS (Netherlands)

Cock, M.J.W.; Lenteren, van J.C.; Brodeur, J.; Barratt, I.P.; Bigler, F.; Bolckmans, K.; Cônsoli, F.L.; Haas, F.; Mason, P.G.; Parra, J.R.P.

2010-01-01

Under the Convention on Biological Diversity (CBD) countries have sovereign rights over their genetic resources. Agreements governing the access to these resources and the sharing of the benefits arising from their use need to be established between involved parties [i.e. Access and Benefit Sharing

West Hackberry Strategic Petroleum Reserve site brine disposal monitoring, Year I report. Volume V. Supporting data for estuarine hydrology, discharge plume analysis, chemical oceanography, biological oceanography, and data management. Final report

Energy Technology Data Exchange (ETDEWEB)

DeRouen, L.R.; Hann, R.W.; Casserly, D.M.; Giammona, C.; Lascara, V.J. (eds.)

1983-02-01

This project centers around the Strategic Petroleum Site (SPR) known as the West Hackberry salt dome which located in southwestern Louisiana, and which is designed to store 241 million barrels of crude oil. Oil storage caverns are formed by injecting water into salt deposits, and pumping out the resulting brine. Studies described in this report were designed as follow-on studies to three months of pre-discharge characterization work, and include data collected during the first year of brine leaching operations. The objectives were to: (1) characterize the environment in terms of physical, chemical and biological attributes; (2) determine if significant adverse changes in ecosystem productivity and stability of the biological community are occurring as a result of brine discharge; and (3) determine the magnitude of any change observed. Volume V contains appendices for the following: supporting data for estuarine hydrology and hydrography; supporting data analysis of discharge plume; supporting data for water and sediment chemistry; CTD/DO and pH profiles during biological monitoring; supporting data for nekton; and supporting data for data management.

The reflection of life functional entailment and imminence in relational biology

CERN Document Server

Louie, A H

2013-01-01

A. H. Louie’s The Reflection of Life: Functional Entailment and Imminence in Relational Biology is a continuation of the exploratory journey in relational biology which began with his 2009 monograph More Than Life Itself: A Synthetic Continuation in Relational Biology. The theme of his first book was ‘What is life?’; the theme of this sequel is “How do two life forms interact?” Biology is a subject concerned with organization of relations. Relational biology is the approach that advocates ‘function dictates structure”, rather than ‘structure implies function’. It is mathematics decoded into biological realizations. The book demonstrates some of the powers of the approach of relational biology, and illustrates how pertinent problems in biology can be better addressed this way. In the first volume the theory was developed by using partially ordered sets, lattices, simulations, models, Aristotle’s four causes, graphs, categories, simple and complex systems, anticipatory systems, and metabolis...

Nonlinear Oscillations in Biology and Chemistry

CERN Document Server

1986-01-01

This volume contains the proceedings of a meeting entitled 'Nonlinear Oscillations in Biology and Chemistry', which was held at the University of Utah May 9-11,1985. The papers fall into four major categories: (i) those that deal with biological problems, particularly problems arising in cell biology, (ii) those that deal with chemical systems, (iii) those that treat problems which arise in neurophysiology, and (iv), those whose primary emphasis is on more general models and the mathematical techniques involved in their analysis. Except for the paper by Auchmuty, all are based on talks given at the meeting. The diversity of papers gives some indication of the scope of the meeting, but the printed word conveys neither the degree of interaction between the participants nor the intellectual sparks generated by that interaction. The meeting was made possible by the financial support of the Department of Mathe­ matics of the University of Utah. I am indebted to Ms. Toni Bunker of the Department of Mathematics for...

Biological Control Strategies for Mosquito Vectors of Arboviruses.

Science.gov (United States)

Huang, Yan-Jang S; Higgs, Stephen; Vanlandingham, Dana L

2017-02-10

Historically, biological control utilizes predatory species and pathogenic microorganisms to reduce the population of mosquitoes as disease vectors. This is particularly important for the control of mosquito-borne arboviruses, which normally do not have specific antiviral therapies available. Although development of resistance is likely, the advantages of biological control are that the resources used are typically biodegradable and ecologically friendly. Over the past decade, the advancement of molecular biology has enabled optimization by the manipulation of genetic materials associated with biological control agents. Two significant advancements are the discovery of cytoplasmic incompatibility induced by Wolbachia bacteria, which has enhanced replacement programs, and the introduction of dominant lethal genes into local mosquito populations through the release of genetically modified mosquitoes. As various arboviruses continue to be significant public health threats, biological control strategies have evolved to be more diverse and become critical tools to reduce the disease burden of arboviruses.

Reliability and Accuracy of Brain Volume Measurement on MR Imaging

DEFF Research Database (Denmark)

Yamagchii, Kechiro; Lassen, Anders; Ring, Poul

1998-01-01

Yamaguchi, K., Lassen, A. And Ring, P. Reliability and Accuracy of Brain Volume Measurement on MR Imaging. Abstract at ESMRMB98 European Society for Magnetic Resonance in Medicine and Biology, Geneva, Sept 17-20, 1998 Danish Research Center for Magnetic Resonance, Hvidovre University Hospital...

MECs: "Building Blocks" for Creating Biological and Chemical Instruments.

Directory of Open Access Journals (Sweden)

Douglas A Hill

Full Text Available The development of new biological and chemical instruments for research and diagnostic applications is often slowed by the cost, specialization, and custom nature of these instruments. New instruments are built from components that are drawn from a host of different disciplines and not designed to integrate together, and once built, an instrument typically performs a limited number of tasks and cannot be easily adapted for new applications. Consequently, the process of inventing new instruments is very inefficient, especially for researchers or clinicians in resource-limited settings. To improve this situation, we propose that a family of standardized multidisciplinary components is needed, a set of "building blocks" that perform a wide array of different tasks and are designed to integrate together. Using these components, scientists, engineers, and clinicians would be able to build custom instruments for their own unique needs quickly and easily. In this work we present the foundation of this set of components, a system we call Multifluidic Evolutionary Components (MECs. "Multifluidic" conveys the wide range of fluid volumes MECs operate upon (from nanoliters to milliliters and beyond; "multi" also reflects the multiple disciplines supported by the system (not only fluidics but also electronics, optics, and mechanics. "Evolutionary" refers to the design principles that enable the library of MEC parts to easily grow and adapt to new applications. Each MEC "building block" performs a fundamental function that is commonly found in biological or chemical instruments, functions like valving, pumping, mixing, controlling, and sensing. Each MEC also has a unique symbol linked to a physical definition, which enables instruments to be designed rapidly and efficiently using schematics. As a proof-of-concept, we use MECs to build a variety of instruments, including a fluidic routing and mixing system capable of manipulating fluid volumes over five orders

Timber resource statistics for Washington, January 1, 1973.

Science.gov (United States)

Patricia M. Bassett; Grover A. Choate

1974-01-01

Timber resource statistics to January 1, 1973, for the State of Washington show total land area, commercial timberland area, and growing stock and sawtimber inventory volumes by county and owner group. Growth and removals are shown by Forest Survey inventory unit for 1972. Each National Forest is updated to January 1, 1973.

Natural Resource Information System. Volume 2: System operating procedures and instructions

Science.gov (United States)

1972-01-01

A total computer software system description is provided for the prototype Natural Resource Information System designed to store, process, and display data of maximum usefulness to land management decision making. Program modules are described, as are the computer file design, file updating methods, digitizing process, and paper tape conversion to magnetic tape. Operating instructions for the system, data output, printed output, and graphic output are also discussed.

Shaping Biological Knowledge: Applications in Proteomics

Directory of Open Access Journals (Sweden)

R. Appel

2006-04-01

Full Text Available The central dogma of molecular biology has provided a meaningful principle for data integration in the field of genomics. In this context, integration reflects the known transitions from a chromosome to a protein sequence: transcription, intron splicing, exon assembly and translation. There is no such clear principle for integrating proteomics data, since the laws governing protein folding and interactivity are not quite understood. In our effort to bring together independent pieces of information relative to proteins in a biologically meaningful way, we assess the bias of bioinformatics resources and consequent approximations in the framework of small-scale studies. We analyse proteomics data while following both a data-driven (focus on proteins smaller than 10 kDa and a hypothesis-driven (focus on whole bacterial proteomes approach. These applications are potentially the source of specialized complements to classical biological ontologies.

Shaping biological knowledge: applications in proteomics.

Science.gov (United States)

Lisacek, F; Chichester, C; Gonnet, P; Jaillet, O; Kappus, S; Nikitin, F; Roland, P; Rossier, G; Truong, L; Appel, R

2004-01-01

The central dogma of molecular biology has provided a meaningful principle for data integration in the field of genomics. In this context, integration reflects the known transitions from a chromosome to a protein sequence: transcription, intron splicing, exon assembly and translation. There is no such clear principle for integrating proteomics data, since the laws governing protein folding and interactivity are not quite understood. In our effort to bring together independent pieces of information relative to proteins in a biologically meaningful way, we assess the bias of bioinformatics resources and consequent approximations in the framework of small-scale studies. We analyse proteomics data while following both a data-driven (focus on proteins smaller than 10 kDa) and a hypothesis-driven (focus on whole bacterial proteomes) approach. These applications are potentially the source of specialized complements to classical biological ontologies.

Marijuana smoking: effects of varying puff volume and breathhold duration.

Science.gov (United States)

Azorlosa, J L; Greenwald, M K; Stitzer, M L

1995-02-01

Two studies were conducted to quantify biological and behavioral effects resulting from exposure to controlled doses of marijuana smoke. In one study, puff volume (30, 60 and 90 ml) and in a second study, breathhold duration (0, 10 and 20 sec) were systematically varied while holding constant other smoking topography parameters (number of puffs = 10, interpuff interval = 60 sec and inhalation volume = 25% of vital capacity). Each study also varied levels of delta 9-tetrahydro-cannabinol marijuana cigarette content (1.75% and 3.55%). Regular marijuana users served as subjects (n = 7 in each experiment). Subjects smoked 10 puffs in each of six sessions; a seventh, nonsmoking session (all measures recorded at the same times as in active smoking sessions) served as a control. Variations in puff volume produced significant dose-related changes in postsmoking plasma delta 9-tetrahydro-cannabinol levels, carbon monoxide boost and subjective effects (e.g., "high"). In contrast, breathholding for 10 or 20 sec versus 0 sec increased plasma delta 9-tetrahydro-cannabinol levels but not CO boost or subjective effects. Task performance measures were not reliably influenced by marijuana smoke exposure within the dosing ranges examined. These findings confirm the utility of the controlled smoking technology, support the notion that cumulative puff volume systematically influences biological exposure and subjective effects, but cast doubt on the common belief that prolonged breathholding of marijuana smoke enhances classical subjective effects associated with its reinforcing value in humans.

Synthetic Biology and the Translational Imperative.

Science.gov (United States)

Heidari Feidt, Raheleh; Ienca, Marcello; Elger, Bernice Simone; Folcher, Marc

2017-12-18

Advances at the interface between the biological sciences and engineering are giving rise to emerging research fields such as synthetic biology. Harnessing the potential of synthetic biology requires timely and adequate translation into clinical practice. However, the translational research enterprise is currently facing fundamental obstacles that slow down the transition of scientific discoveries from the laboratory to the patient bedside. These obstacles including scarce financial resources and deficiency of organizational and logistic settings are widely discussed as primary impediments to translational research. In addition, a number of socio-ethical considerations inherent in translational research need to be addressed. As the translational capacity of synthetic biology is tightly linked to its social acceptance and ethical approval, ethical limitations may-together with financial and organizational problems-be co-determinants of suboptimal translation. Therefore, an early assessment of such limitations will contribute to proactively favor successful translation and prevent the promising potential of synthetic biology from remaining under-expressed. Through the discussion of two case-specific inventions in synthetic biology and their associated ethical implications, we illustrate the socio-ethical challenges ahead in the process of implementing synthetic biology into clinical practice. Since reducing the translational lag is essential for delivering the benefits of basic biomedical research to society at large and promoting global health, we advocate a moral obligation to accelerating translational research: the "translational imperative."

IMRT optimization with pseudo-biologic objective function

International Nuclear Information System (INIS)

Yi, B. Y.; Ahn, S. D.; Kim, J. H.; Lee, S. W.; Choi, E. K.

2002-01-01

The pseudo-biologic objective function has been proposed for the IMRT optimization. It is similar to the biological objective function in mathematical shape, but uses physical parameters. The pseudo-biologic objective function concept is consisted of the target coverage index (TCI) and the organ score index (OSI), was introduced. The TCI was expressed as the sum of all of the weighted bins of target dose volume histogram (DVH). The weights were given as the normal distribution of which the average is 100 % and the standard deviation is ±. The OSI was expressed as similar way. The average of the normal distribution was 0% of the dose and that of standard deviation was selected as a function of limiting dose and its importance. The objective function could be calculated as the product of the TCI and OSI's. The RTP Tool Box (RTB) was used for this study. The constraints applied in the optimization was intuitively clinical experience based numbers, while the physical objective function asks just numbers which are not necessarily based on the clinic, and the parameters for the biologic objective functions are uncertain. The OSI's from the pseudo-biological function showed better results than from the physical functions, while TCI's showed similar tendency. We could show that the pseudo-biologic function can be used for an IMRT objective function on behalf of the biological objective function

Nanofluidic device for continuous multiparameter quality assurance of biologics.

Science.gov (United States)

Ko, Sung Hee; Chandra, Divya; Ouyang, Wei; Kwon, Taehong; Karande, Pankaj; Han, Jongyoon

2017-08-01

Process analytical technology (PAT) is critical for the manufacture of high-quality biologics as it enables continuous, real-time and on-line/at-line monitoring during biomanufacturing processes. The conventional analytical tools currently used have many restrictions to realizing the PAT of current and future biomanufacturing. Here we describe a nanofluidic device for the continuous monitoring of biologics' purity and bioactivity with high sensitivity, resolution and speed. Periodic and angled nanofilter arrays served as the molecular sieve structures to conduct a continuous size-based analysis of biologics. A multiparameter quality monitoring of three separate commercial biologic samples within 50 minutes has been demonstrated, with 20 µl of sample consumption, inclusive of dead volume in the reservoirs. Additionally, a proof-of-concept prototype system, which integrates an on-line sample-preparation system and the nanofluidic device, was demonstrated for at-line monitoring. Thus, the system is ideal for on-site monitoring, and the real-time quality assurance of biologics throughout the biomanufacturing processes.

Improving integrative searching of systems chemical biology data using semantic annotation.

Science.gov (United States)

Chen, Bin; Ding, Ying; Wild, David J

2012-03-08

Systems chemical biology and chemogenomics are considered critical, integrative disciplines in modern biomedical research, but require data mining of large, integrated, heterogeneous datasets from chemistry and biology. We previously developed an RDF-based resource called Chem2Bio2RDF that enabled querying of such data using the SPARQL query language. Whilst this work has proved useful in its own right as one of the first major resources in these disciplines, its utility could be greatly improved by the application of an ontology for annotation of the nodes and edges in the RDF graph, enabling a much richer range of semantic queries to be issued. We developed a generalized chemogenomics and systems chemical biology OWL ontology called Chem2Bio2OWL that describes the semantics of chemical compounds, drugs, protein targets, pathways, genes, diseases and side-effects, and the relationships between them. The ontology also includes data provenance. We used it to annotate our Chem2Bio2RDF dataset, making it a rich semantic resource. Through a series of scientific case studies we demonstrate how this (i) simplifies the process of building SPARQL queries, (ii) enables useful new kinds of queries on the data and (iii) makes possible intelligent reasoning and semantic graph mining in chemogenomics and systems chemical biology. Chem2Bio2OWL is available at http://chem2bio2rdf.org/owl. The document is available at http://chem2bio2owl.wikispaces.com.

Insects: an underrepresented resource for the discovery of biologically active natural products

Directory of Open Access Journals (Sweden)

Lauren Seabrooks

2017-07-01

Full Text Available Nature has been the source of life-changing and -saving medications for centuries. Aspirin, penicillin and morphine are prime examples of Nature׳s gifts to medicine. These discoveries catalyzed the field of natural product drug discovery which has mostly focused on plants. However, insects have more than twice the number of species and entomotherapy has been in practice for as long as and often in conjunction with medicinal plants and is an important alternative to modern medicine in many parts of the world. Herein, an overview of current traditional medicinal applications of insects and characterization of isolated biologically active molecules starting from approximately 2010 is presented. Insect natural products reviewed were isolated from ants, bees, wasps, beetles, cockroaches, termites, flies, true bugs, moths and more. Biological activities of these natural products from insects include antimicrobial, antifungal, antiviral, anticancer, antioxidant, anti-inflammatory and immunomodulatory effects.

Engineering assessment and feasibility study of Chattanooga Shale as a future source of uranium

International Nuclear Information System (INIS)

1978-06-01

This volume contains five appendixes: Chattanooga Shale preliminary mining study, soils data, meteorologic data, water resources data, and biological resource data. The area around DeKalb County in Tennessee is the most likely site for commercial development for recovery of uranium

The Electron Microscopy Outreach Program: A Web-based resource for research and education.

Science.gov (United States)

Sosinsky, G E; Baker, T S; Hand, G; Ellisman, M H

1999-01-01

We have developed a centralized World Wide Web (WWW)-based environment that serves as a resource of software tools and expertise for biological electron microscopy. A major focus is molecular electron microscopy, but the site also includes information and links on structural biology at all levels of resolution. This site serves to help integrate or link structural biology techniques in accordance with user needs. The WWW site, called the Electron Microscopy (EM) Outreach Program (URL: http://emoutreach.sdsc.edu), provides scientists with computational and educational tools for their research and edification. In particular, we have set up a centralized resource containing course notes, references, and links to image analysis and three-dimensional reconstruction software for investigators wanting to learn about EM techniques either within or outside of their fields of expertise. Copyright 1999 Academic Press.

CADDIS Volume 4. Data Analysis: Predicting Environmental Conditions from Biological Observations (PECBO Appendix)

Science.gov (United States)

Overview of PECBO Module, using scripts to infer environmental conditions from biological observations, statistically estimating species-environment relationships, methods for inferring environmental conditions, statistical scripts in module.

Proceedings of the European medical and biological engineering conference EMBEC '99 (Part I)

International Nuclear Information System (INIS)

Rehak, P.; Hutten, H.

1999-01-01

The proceedings books of the EMBEC '99 - European Medical and Biological Engineering Conference - are published in two parts as supplement 2 to the volume 37 of 'Medical and Biological Engineering and Computing', the official journal of the International Federation for Medical and Biological Engineering. More then 800 papers have been arranged in the order of the main topics and the topics of the special sessions of the conference. The paper of INIS relevance were worked up for INIS data bank. (author)

Interactomes to Biological Phase Space: a call to begin thinking at a new level in computational biology.

Energy Technology Data Exchange (ETDEWEB)

Davidson, George S.; Brown, William Michael

2007-09-01

Techniques for high throughput determinations of interactomes, together with high resolution protein collocalizations maps within organelles and through membranes will soon create a vast resource. With these data, biological descriptions, akin to the high dimensional phase spaces familiar to physicists, will become possible. These descriptions will capture sufficient information to make possible realistic, system-level models of cells. The descriptions and the computational models they enable will require powerful computing techniques. This report is offered as a call to the computational biology community to begin thinking at this scale and as a challenge to develop the required algorithms and codes to make use of the new data.3

Type A natural resource damage assessment models for Great Lakes environments (NRDAM/GLE) and coastal and marine environments (NRDAM/CME)

International Nuclear Information System (INIS)

French, D.P.; Reed, M.

1993-01-01

A computer model of the physical fates, biological effects, and economic damages resulting from releases of oil and other hazardous materials has been developed by ASA to be used in Type A natural resource damage assessments under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Natural Resource Damage Assessment Models for Great Lakes Environments (NRDAM/GLE) and for Coastal and Marine Environments (NRDAM/GLE) and for Coastal and Marine Environments (NRDAM/CME) will become available. These models will also support NOAA's damage assessment regulations under the Oil Pollution Act of 1990. The physical and biological models are three-dimensional. Direct mortality from toxic concentrations and oiling, impacts of habitat loss, and food web losses are included in the model. Estimation of natural resource damages is based both on the lost value of injured resources and on the costs for restoration or replacement of those resources. A coupled geographical information system (GIS) allows gridded representation of complex coastal boundaries, variable bathymetry, shoreline types, and multiple biological habitats. The models contain environmental, geographical, chemical, toxicological, biological, restoration and economic databases with the necessary information to estimate damages. Chemical and toxicological data are included for about 470 chemicals and oils. Biological data are unique to 77 coastal and marine plus 11 Great Lakes provinces, and to habitat type. Restoration and economic valuations are also regionally specific

Synthetic and systems biology for microbial production of commodity chemicals.

Science.gov (United States)

Chubukov, Victor; Mukhopadhyay, Aindrila; Petzold, Christopher J; Keasling, Jay D; Martín, Héctor García

2016-01-01

The combination of synthetic and systems biology is a powerful framework to study fundamental questions in biology and produce chemicals of immediate practical application such as biofuels, polymers, or therapeutics. However, we cannot yet engineer biological systems as easily and precisely as we engineer physical systems. In this review, we describe the path from the choice of target molecule to scaling production up to commercial volumes. We present and explain some of the current challenges and gaps in our knowledge that must be overcome in order to bring our bioengineering capabilities to the level of other engineering disciplines. Challenges start at molecule selection, where a difficult balance between economic potential and biological feasibility must be struck. Pathway design and construction have recently been revolutionized by next-generation sequencing and exponentially improving DNA synthesis capabilities. Although pathway optimization can be significantly aided by enzyme expression characterization through proteomics, choosing optimal relative protein expression levels for maximum production is still the subject of heuristic, non-systematic approaches. Toxic metabolic intermediates and proteins can significantly affect production, and dynamic pathway regulation emerges as a powerful but yet immature tool to prevent it. Host engineering arises as a much needed complement to pathway engineering for high bioproduct yields; and systems biology approaches such as stoichiometric modeling or growth coupling strategies are required. A final, and often underestimated, challenge is the successful scale up of processes to commercial volumes. Sustained efforts in improving reproducibility and predictability are needed for further development of bioengineering.

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education.