WorldWideScience

Sample records for biological resources branch

  1. Branching processes in biology

    CERN Document Server

    Kimmel, Marek

    2015-01-01

    This book provides a theoretical background of branching processes and discusses their biological applications. Branching processes are a well-developed and powerful set of tools in the field of applied probability. The range of applications considered includes molecular biology, cellular biology, human evolution and medicine. The branching processes discussed include Galton-Watson, Markov, Bellman-Harris, Multitype, and General Processes. As an aid to understanding specific examples, two introductory chapters, and two glossaries are included that provide background material in mathematics and in biology. The book will be of interest to scientists who work in quantitative modeling of biological systems, particularly probabilists, mathematical biologists, biostatisticians, cell biologists, molecular biologists, and bioinformaticians. The authors are a mathematician and cell biologist who have collaborated for more than a decade in the field of branching processes in biology for this new edition. This second ex...

  2. Policy Analysis and Science Assistance Branch : Integrating Social, Behavioral, Economic and Biological Sciences

    Science.gov (United States)

    2010-01-01

    The Fort Collins Science Center's Policy Analysis and Science Assistance (PASA) Branch is a team of approximately 22 scientists, technicians, and graduate student researchers. PASA provides unique capabilities in the U.S. Geological Survey by leading projects that integrate social, behavioral, economic, and biological analyses in the context of human-natural resource interactions. Resource planners, managers, and policymakers in the U.S. Departments of the Interior (DOI) and Agriculture (USDA), State and local agencies, as well as international agencies use information from PASA studies to make informed natural resource management and policy decisions. PASA scientists' primary functions are to conduct both theoretical and applied social science research, provide technical assistance, and offer training to advance performance in policy relevant research areas. Management and research issues associated with human-resource interactions typically occur in a unique context, involve difficult to access populations, require knowledge of both natural/biological science in addition to social science, and require the skill to integrate multiple science disciplines. In response to these difficult contexts, PASA researchers apply traditional and state-of-the-art social science methods drawing from the fields of sociology, demography, economics, political science, communications, social-psychology, and applied industrial organization psychology. Social science methods work in concert with our rangeland/agricultural management, wildlife, ecology, and biology capabilities. The goal of PASA's research is to enhance natural resource management, agency functions, policies, and decision-making. Our research is organized into four broad areas of study.

  3. A Branch-and-Cut Algorithm for Elementary Shortest Path Problem with Resource Constraints

    DEFF Research Database (Denmark)

    Jepsen, Mads Kehlet; Petersen, Bjørn; Spoorendonk, Simon

    The elementary shortest path with resource constraints are commonly solved with dynamic programming algorithms. We present a branch-and-cut algorithm for the undirected version. Two types of resources are discussed: A capacity and a fixed charge resource. The former is the subproblem of the capac...... of the capacitated vehicle routing problem and the latter is for the split delivery version....

  4. Management, Resources and Reproductive Biology

    Directory of Open Access Journals (Sweden)

    Bernard Wallner

    2014-10-01

    Full Text Available This work presents a relationship between environmental conditions and reproductive performance in modern humans. Birth rates and sex ratio (SRB at birth were analyzed from large data scales. The results include data from people working or living under different job respectively socio-economic conditions, such as employees working in the academic field, employees under supervisory or hire and fire conditions, and people who have better access to resources. The results show that employees who have better jobs and earn more money do have more children and females under better socio-economic conditions do give birth to more sons. In conclusion, it is suggested that different socio-economic environmental conditions may have an impact on female and male birth rates and SRBs, which may be related to stress perception rates.

  5. A branch-and-cut algorithm for the elementary shortest path problem with resource constraints

    DEFF Research Database (Denmark)

    Jepsen, Mads Kehlet; Petersen, Bjørn; Spoorendonk, Simon

    The elementary shortest path with resource constraints have commonly been solved with dynamic programming algorithms. Assuming an undirected graph, we present a compact formulation of this problem and a branch-and-cut algorithm to solve it. Two types of resources are discussed: a capacity...... and a fixed charge resource. The former is the subproblem of the capacitated vehicle routing problem and the latter is from the split delivery version. Computational results are presented and compared to dynamic programming algorithms....

  6. Fort Collins Science Center- Policy Analysis and Science Assistance Branch : Integrating social, behavioral, economic and biological sciences

    Science.gov (United States)

    2010-01-01

    The Fort Collins Science Center's Policy Analysis and Science Assistance (PASA) Branch is a team of approximately 22 scientists, technicians, and graduate student researchers. PASA provides unique capabilities in the U.S. Geological Survey by leading projects that integrate social, behavioral, economic, and biological analyses in the context of human-natural resource interactions. Resource planners, managers, and policymakers in the U.S. Departments of the Interior (DOI) and Agriculture (USDA), State and local agencies, as well as international agencies use information from PASA studies to make informed natural resource management and policy decisions. PASA scientists' primary functions are to conduct both theoretical and applied social science research, provide technical assistance, and offer training to advance performance in policy relevant research areas. Management and research issues associated with human-resource interactions typically occur in a unique context, involve difficult to access populations, require knowledge of both natural/biological science in addition to social science, and require the skill to integrate multiple science disciplines. In response to these difficult contexts, PASA researchers apply traditional and state-of-the-art social science methods drawing from the fields of sociology, demography, economics, political science, communications, social-psychology, and applied industrial organization psychology. Social science methods work in concert with our rangeland/agricultural management, wildlife, ecology, and biology capabilities. The goal of PASA's research is to enhance natural resource management, agency functions, policies, and decision-making. Our research is organized into four broad areas of study.

  7. Prospects of Biological Resources in Mitigating Agricultural Disasters

    Institute of Scientific and Technical Information of China (English)

    WANG Shaonan; YE Zhihua; YU Dazhao

    2001-01-01

    This paper analyzes the agricultural impacts of meteorological disasters, such as flood and drought, and biological disasters such as crop diseases, insect pests, weeds and rodents; and elaborates that efficacious development and utilization of biological resources are an effective way to preventing and mitigating agricultural disasters. Subjects for research on the development of biological resources are identified.

  8. Make It Go Viral! Rate-optimal Control for Resource-Constrained Branching Processes

    CERN Document Server

    Xu, Kuang

    2012-01-01

    We propose a new class of controlled multi-type branching processes with a per-step linear resource constraint, motivated by applications in quantitative marketing, and study the associated growth-rate maximizing control strategies. We show that the optimal growth rate can be achieved by maintaining a single optimal ratio among different population types, for both deterministic and stochastic branching processes. In the special case of a two-type population and with a symmetric revenue structure, the optimal ratio is obtained in closed-form. As a proof of concept, the methodology is applied to the linkage structure of the 2004 US Presidential Election blogosphere, where the optimal growth rate achieves sizable gains over a uniform selection strategy.

  9. Vector of development of prospecting branch in the conditions of exhaustion of raw material resources

    Directory of Open Access Journals (Sweden)

    Andrei Zastypov

    2014-04-01

    Full Text Available Exhaustion of oil resources in many oil-extracting regions staticizes a problem of development of mechanisms of economic incentives of activity of the prospecting companies, effective regulation of tax system and its adaptation to needs of development of oil-extracting and prospecting branches. Offers on rational use of investment means in geological exploration and to justification of administrative decisions are considered. The main questions of tax and investment incentives of activity in the subsurface use sphere in the conditions of insufficiency of financing of prospecting works are taken up.

  10. A Branch and Bound Algorithm for Project Scheduling Problem with Spatial Resource Constraints

    Directory of Open Access Journals (Sweden)

    Shicheng Hu

    2015-01-01

    Full Text Available With respect to the block assembly schedule in a shipbuilding enterprise, a spatial resource constrained project scheduling problem (SRCPSP is proposed, which aims to minimize the makespan of a project under the constraints of the availability of a two-dimensional spatial resource and the precedence relationship between tasks. In order to solve SRCPSP to the optimum, a branch and bound algorithm (BB is developed. For the BB-SRCPSP, first, an implicitly enumerative branch scheme is presented. Secondly, a precedence based lower bound, as well as an effective dominance rule, is employed for pruning. Next, a heuristic based algorithm is used to decide the order of a node to be selected for expansion such that the efficiency of the algorithm is further improved. In addition, a maximal space based arrangement is applied to the configuration of the areas required each day in an available area. Finally, the simulation experiment is conducted to illustrate the effectiveness of the BB-SRCPSP.

  11. Biological data resources at the embl-ebi

    OpenAIRE

    Rodrigo Lopez

    2009-01-01

    The European Bioinformatics Institute (EBI) is an Outstation of the European Molecular Biology Laboratory (EMBL). These are Europe’s flagships in bioinforma­tics and basic research in molecular biology. The EBI has been maintaining core data resources in molecular biology for 15 years and is notionally custodian to the largest collection of databases and services in Life Sciences in Europe. EBI provides access in a free and unrestricted fashion to these resources to the international resear...

  12. Fort Collins Science Center Ecosystem Dynamics branch--interdisciplinary research for addressing complex natural resource issues across landscapes and time

    Science.gov (United States)

    Bowen, Zachary H.; Melcher, Cynthia P.; Wilson, Juliette T.

    2013-01-01

    The Ecosystem Dynamics Branch of the Fort Collins Science Center offers an interdisciplinary team of talented and creative scientists with expertise in biology, botany, ecology, geology, biogeochemistry, physical sciences, geographic information systems, and remote-sensing, for tackling complex questions about natural resources. As demand for natural resources increases, the issues facing natural resource managers, planners, policy makers, industry, and private landowners are increasing in spatial and temporal scope, often involving entire regions, multiple jurisdictions, and long timeframes. Needs for addressing these issues include (1) a better understanding of biotic and abiotic ecosystem components and their complex interactions; (2) the ability to easily monitor, assess, and visualize the spatially complex movements of animals, plants, water, and elements across highly variable landscapes; and (3) the techniques for accurately predicting both immediate and long-term responses of system components to natural and human-caused change. The overall objectives of our research are to provide the knowledge, tools, and techniques needed by the U.S. Department of the Interior, state agencies, and other stakeholders in their endeavors to meet the demand for natural resources while conserving biodiversity and ecosystem services. Ecosystem Dynamics scientists use field and laboratory research, data assimilation, and ecological modeling to understand ecosystem patterns, trends, and mechanistic processes. This information is used to predict the outcomes of changes imposed on species, habitats, landscapes, and climate across spatiotemporal scales. The products we develop include conceptual models to illustrate system structure and processes; regional baseline and integrated assessments; predictive spatial and mathematical models; literature syntheses; and frameworks or protocols for improved ecosystem monitoring, adaptive management, and program evaluation. The descriptions

  13. Resources and Biological Activities of Natural Polyphenols

    Directory of Open Access Journals (Sweden)

    An-Na Li

    2014-12-01

    Full Text Available The oxidative stress imposed by reactive oxygen species (ROS plays an important role in many chronic and degenerative diseases. As an important category of phytochemicals, phenolic compounds universally exist in plants, and have been considered to have high antioxidant ability and free radical scavenging capacity, with the mechanism of inhibiting the enzymes responsible for ROS production and reducing highly oxidized ROS. Therefore, phenolic compounds have attracted increasing attention as potential agents for preventing and treating many oxidative stress-related diseases, such as cardiovascular diseases, cancer, ageing, diabetes mellitus and neurodegenerative diseases. This review summarizes current knowledge of natural polyphenols, including resource, bioactivities, bioavailability and potential toxicity.

  14. Resources and biological activities of natural polyphenols.

    Science.gov (United States)

    Li, An-Na; Li, Sha; Zhang, Yu-Jie; Xu, Xiang-Rong; Chen, Yu-Ming; Li, Hua-Bin

    2014-12-01

    The oxidative stress imposed by reactive oxygen species (ROS) plays an important role in many chronic and degenerative diseases. As an important category of phytochemicals, phenolic compounds universally exist in plants, and have been considered to have high antioxidant ability and free radical scavenging capacity, with the mechanism of inhibiting the enzymes responsible for ROS production and reducing highly oxidized ROS. Therefore, phenolic compounds have attracted increasing attention as potential agents for preventing and treating many oxidative stress-related diseases, such as cardiovascular diseases, cancer, ageing, diabetes mellitus and neurodegenerative diseases. This review summarizes current knowledge of natural polyphenols, including resource, bioactivities, bioavailability and potential toxicity.

  15. Yucca Mountain Biological Resources Monitoring Program

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a possible site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a repository. To ensure that site characterization activities (SCA) do not adversely affect the Yucca Mountain area, an environmental program has been implemented to monitor and mitigate potential impacts and to ensure that activities comply with applicable environmental regulations. This report describes the activities and accomplishments during fiscal year 1991 (FY91) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Activities Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

  16. Yucca Mountain biological resources monitoring program

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a potential site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities (SCA) do not adversely affect the environment at Yucca Mountain, an environmental program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG ampersand G Energy Measurements, Inc. (EG ampersand G/EM) during fiscal year 1992 (FY92) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

  17. Design and biological properties of iodine-123 labeled β-methyl-branched fatty acids

    International Nuclear Information System (INIS)

    The synthetic strategy, synthesis, preclinical evaluation and potential clinical applications of 3-methyl-branched radioiodinated iodophenyl- and iodovinyl-substituted fatty acids are reviewed for use as myocardial imaging agents. 50 references, 6 figures

  18. Third report on the Oak Ridge K-25 Site Biological Monitoring and Abatement Program for Mitchell Branch

    International Nuclear Information System (INIS)

    As a condition of the modified National Pollutant Discharge Elimination System (NPDES) permit issued to the Oak Ridge Gaseous Diffusion Plant (ORGDP; now referred to as the Oak Ridge K-25 Site) on September 11, 1986, a Biological Monitoring and Abatement Program (BMAP) was developed for the receiving stream (Mitchell Branch or K-1700 stream). On October 1, 1992, a renewed NPDES permit was issued for the K-25 Site. A biological monitoring plan was submitted for Mitchell Branch, Poplar Creek, Poplar Creek Embayment of the Clinch River and any unnamed tributaries of these streams. The objectives of BMAP are to (1) demonstrate that the effluent limitations established for the Oak Ridge K-25 Site protect and maintain the use of Mitchell Branch for growth and propagation of fish and other aquatic life and (2) document the effects on stream biota resulting from operation of major new pollution abatement facilities, including the Central Neutralization Facility (CNF) and the Toxic Substances Control Act (TSCA) incinerator. The BMAP consists of four tasks: (1) toxicity monitoring; (2) bioaccumulation monitoring; (3) assessment of fish health; and (4) instream monitoring of biological communities, including benthic macroinvertebrates and fish. This document, the third in a series, reports on the results of the Oak Ridge K-25 Site BMAP; it describes studies that were conducted over various periods of time between June 1990 and December 1993, although monitoring conducted outside this time period is included, as appropriate

  19. Third report on the Oak Ridge K-25 Site Biological Monitoring and Abatement Program for Mitchell Branch

    Energy Technology Data Exchange (ETDEWEB)

    Hinzman, R.L. [ed.; Adams, S.M.; Ashwood, T.L. [Oak Ridge National Lab., TN (United States)] [and others

    1995-08-01

    As a condition of the modified National Pollutant Discharge Elimination System (NPDES) permit issued to the Oak Ridge Gaseous Diffusion Plant (ORGDP; now referred to as the Oak Ridge K-25 Site) on September 11, 1986, a Biological Monitoring and Abatement Program (BMAP) was developed for the receiving stream (Mitchell Branch or K-1700 stream). On October 1, 1992, a renewed NPDES permit was issued for the K-25 Site. A biological monitoring plan was submitted for Mitchell Branch, Poplar Creek, Poplar Creek Embayment of the Clinch River and any unnamed tributaries of these streams. The objectives of BMAP are to (1) demonstrate that the effluent limitations established for the Oak Ridge K-25 Site protect and maintain the use of Mitchell Branch for growth and propagation of fish and other aquatic life and (2) document the effects on stream biota resulting from operation of major new pollution abatement facilities, including the Central Neutralization Facility (CNF) and the Toxic Substances Control Act (TSCA) incinerator. The BMAP consists of four tasks: (1) toxicity monitoring; (2) bioaccumulation monitoring; (3) assessment of fish health; and (4) instream monitoring of biological communities, including benthic macroinvertebrates and fish. This document, the third in a series, reports on the results of the Oak Ridge K-25 Site BMAP; it describes studies that were conducted over various periods of time between June 1990 and December 1993, although monitoring conducted outside this time period is included, as appropriate.

  20. Geospatial Technology Applications and Infrastructure in the Biological Resources Division

    Science.gov (United States)

    D'Erchia, Frank; Getter, James; D'Erchia, Terry D.; Root, Ralph; Stitt, Susan; White, Barbara

    1998-01-01

    Executive Summary -- Automated spatial processing technology such as geographic information systems (GIS), telemetry, and satellite-based remote sensing are some of the more recent developments in the long history of geographic inquiry. For millennia, humankind has endeavored to map the Earth's surface and identify spatial relationships. But the precision with which we can locate geographic features has increased exponentially with satellite positioning systems. Remote sensing, GIS, thematic mapping, telemetry, and satellite positioning systems such as the Global Positioning System (GPS) are tools that greatly enhance the quality and rapidity of analysis of biological resources. These technologies allow researchers, planners, and managers to more quickly and accurately determine appropriate strategies and actions. Researchers and managers can view information from new and varying perspectives using GIS and remote sensing, and GPS receivers allow the researcher or manager to identify the exact location of interest. These geospatial technologies support the mission of the U.S. Geological Survey (USGS) Biological Resources Division (BRD) and the Strategic Science Plan (BRD 1996) by providing a cost-effective and efficient method for collection, analysis, and display of information. The BRD mission is 'to work with others to provide the scientific understanding and technologies needed to support the sound management and conservation of our Nation's biological resources.' A major responsibility of the BRD is to develop and employ advanced technologies needed to synthesize, analyze, and disseminate biological and ecological information. As the Strategic Science Plan (BRD 1996) states, 'fulfilling this mission depends on effectively balancing the immediate need for information to guide management of biological resources with the need for technical assistance and long-range, strategic information to understand and predict emerging patterns and trends in ecological systems

  1. 3rd Workshop on Branching Processes and their Applications

    CERN Document Server

    González, Miguel; Gutiérrez, Cristina; Martínez, Rodrigo; Minuesa, Carmen; Molina, Manuel; Mota, Manuel; Ramos, Alfonso; WBPA15

    2016-01-01

    This volume gathers papers originally presented at the 3rd Workshop on Branching Processes and their Applications (WBPA15), which was held from 7 to 10 April 2015 in Badajoz, Spain (http://branching.unex.es/wbpa15/index.htm). The papers address a broad range of theoretical and practical aspects of branching process theory. Further, they amply demonstrate that the theoretical research in this area remains vital and topical, as well as the relevance of branching concepts in the development of theoretical approaches to solving new problems in applied fields such as Epidemiology, Biology, Genetics, and, of course, Population Dynamics. The topics covered can broadly be classified into the following areas: 1. Coalescent Branching Processes 2. Branching Random Walks 3. Population Growth Models in Varying and Random Environments 4. Size/Density/Resource-Dependent Branching Models 5. Age-Dependent Branching Models 6. Special Branching Models 7. Applications in Epidemiology 8. Applications in Biology and Genetics Offer...

  2. Investigating the impact of performance management on human resource performance across head offices of Agricultural bank branches in Tehran

    Directory of Open Access Journals (Sweden)

    Mir Hamid Reza Torabi Shahidi

    2013-08-01

    Full Text Available Human resource is one of the most precious assets across contemporary organizations and companies. For this reason, enterprises have to invest on them to promote and improve their employees’ performance. An effective mechanism to develop corporate and human performance is to design and establish a system of performance management so that it improves employees’ performance by determining explicit organizational objectives and coordinating them with individual goals.Current work aims to determine the impact of performance management on human resource performance across head offices of Agricultural Bank branches in Tehran (the main goal and prioritize among performance management components and human resource performance components and also present some procedures to improve human performance using performance management components (sub-goals.

  3. Second report on the Oak Ridge K-25 Site Biological Monitoring and Abatement Program for Mitchell Branch

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.G. [ed.; Adams, S.M.; Hinzman, R.L.; Kszos, L.A.; Loar, J.M.; Peterson, M.J.; Ryon, M.G.; Southworth, G.R. [Oak Ridge National Lab., TN (United States); Crumby, W.D. [Automated Sciences Group, Inc., Oak Ridge, TN (United States)

    1994-03-01

    On September 11, 1986, a modified National Pollutant Discharge Elimination System permit was issued for the Oak Ridge Gaseous Diffusion Plant (ORGDP; now referred to as the Oak Ridge K-25 Site), a former uranium-enrichment production facility. As required in Part III of the permit, a Biological Monitoring and Abatement Program (BMAP) was developed for the biological monitoring of Mitchell Branch (K-1700 stream) and submitted for approval to the US EPA and the Tennessee Department of Environment and Conservation. The plan described biomonitoring activities that would be conducted over the duration of the permit. The objectives of the BMAP are to demonstrate that the effluent limitations established for the Oak Ridge K-25 Site protect and maintain the use of Mitchell Branch for growth and propagation of fish and other aquatic life, and to document the effects on stream biota resulting from operation of major new pollution abatement facilities. The BMAP consists of four tasks: ambient toxicity testing; bioaccumulation studies; biological indicator studies; and ecological surveys of stream communities, including benthic macroinvertebrates and fish. This document is the second in a series of reports presenting the results of the studies that were conducted over various periods of time between August 1987 and June 1990.

  4. A history of the Water Resources Branch of the United States Geological Survey: vol. II, years of increasing cooperation, July 1, 1919 to June 30, 1928

    Science.gov (United States)

    Follansbee, Robert

    1953-01-01

    This volume of the History of the Water Resources Branch of the United States Geological Survey by Robert Follansbee covers the period from July 1, 1919, to June 30, 1928. In conformity with the practice

  5. Mission and spacecraft support functions of the Materials Engineering Branch: A space oriented technology resource

    Science.gov (United States)

    Fisher, A.; Staugaitis, C. L.

    1974-01-01

    The capabilities of the Materials Engineering Branch (MEB) of the Goddard Space Flight Center, Greenbelt, Maryland, are surveyed. The specific functions of spacecraft materials review, materials processing and information dissemination, and laboratory support, are outlined in the Activity Report. Further detail is provided by case histories of laboratory satellite support and equipment. Project support statistics are shown, and complete listings of MEB publications, patents, and tech briefs are included. MEB staff, and their respective discipline areas and spacecraft liaison associations, are listed.

  6. First report on the Oak Ridge K-25 Site Biological Monitoring and Abatement Program for Mitchell Branch

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.G. [ed.; Adams, S.M.; Kszos, L.A.; Ryon, M.G.; Southworth, G.R.; Loar, J.M.

    1993-08-01

    A modified National Pollutant Discharge Elimination System permit was issued to the Oak Ridge Gaseous Diffusion Plant (now referred to as the Oak Ridge K-25 Site) on September 11, 1986. The Oak Ridge K-25 Site is a former uranium-enrichment production facility, which is currently managed by Martin Marietta Energy Systems, Inc. for the US Department of Energy. As required in Part III (L) of that permit, a plan for the biological monitoring of Mitchell Branch (K-1700 stream) was prepared and submitted for approval to the US Environmental Protection Agency and the Tennessee Department of Environment and Conservation [formerly the Tennessee Department of Health and Environment (Loar et al. 1992b)]. The K-25 Site Biological Monitoring and Abatement Program (BMAP) described biomonitoring activities that would be conducted over the duration of the permit. Because it was anticipated that the composition of existing effluent streams entering Mitchell Branch would be altered shortly after the modified permit was issued, sampling of the benthic invertebrate and fish communities (Task 4 of BMAP) was initiated in August and September 1986 respectively.

  7. First report on the Oak Ridge K-25 Site Biological Monitoring and Abatement Program for Mitchell Branch

    International Nuclear Information System (INIS)

    A modified National Pollutant Discharge Elimination System permit was issued to the Oak Ridge Gaseous Diffusion Plant (now referred to as the Oak Ridge K-25 Site) on September 11, 1986. The Oak Ridge K-25 Site is a former uranium-enrichment production facility, which is currently managed by Martin Marietta Energy Systems, Inc. for the US Department of Energy. As required in Part III (L) of that permit, a plan for the biological monitoring of Mitchell Branch (K-1700 stream) was prepared and submitted for approval to the US Environmental Protection Agency and the Tennessee Department of Environment and Conservation [formerly the Tennessee Department of Health and Environment (Loar et al. 1992b)]. The K-25 Site Biological Monitoring and Abatement Program (BMAP) described biomonitoring activities that would be conducted over the duration of the permit. Because it was anticipated that the composition of existing effluent streams entering Mitchell Branch would be altered shortly after the modified permit was issued, sampling of the benthic invertebrate and fish communities (Task 4 of BMAP) was initiated in August and September 1986 respectively

  8. Labour resources of «Physical culture and sport» branch

    OpenAIRE

    Хомко, І.; Лугова, А.

    2011-01-01

    In theses, the results of literary sources are described related to the problem of skilled potential of industry of physical culture and sport. The basic stages of management labour resources are described in organizations of athletic-sporting orientation in Ukraine.

  9. Geometric combinatorics and computational molecular biology: branching polytopes for RNA sequences

    OpenAIRE

    Drellich, Elizabeth; Gainer-Dewar, Andrew; Harrington, Heather A.; He, Qijun; Heitsch, Christine; Poznanović, Svetlana

    2015-01-01

    Questions in computational molecular biology generate various discrete optimization problems, such as DNA sequence alignment and RNA secondary structure prediction. However, the optimal solutions are fundamentally dependent on the parameters used in the objective functions. The goal of a parametric analysis is to elucidate such dependencies, especially as they pertain to the accuracy and robustness of the optimal solutions. Techniques from geometric combinatorics, including polytopes and thei...

  10. CauloBrowser: A systems biology resource for Caulobacter crescentus.

    Science.gov (United States)

    Lasker, Keren; Schrader, Jared M; Men, Yifei; Marshik, Tyler; Dill, David L; McAdams, Harley H; Shapiro, Lucy

    2016-01-01

    Caulobacter crescentus is a premier model organism for studying the molecular basis of cellular asymmetry. The Caulobacter community has generated a wealth of high-throughput spatiotemporal databases including data from gene expression profiling experiments (microarrays, RNA-seq, ChIP-seq, ribosome profiling, LC-ms proteomics), gene essentiality studies (Tn-seq), genome wide protein localization studies, and global chromosome methylation analyses (SMRT sequencing). A major challenge involves the integration of these diverse data sets into one comprehensive community resource. To address this need, we have generated CauloBrowser (www.caulobrowser.org), an online resource for Caulobacter studies. This site provides a user-friendly interface for quickly searching genes of interest and downloading genome-wide results. Search results about individual genes are displayed as tables, graphs of time resolved expression profiles, and schematics of protein localization throughout the cell cycle. In addition, the site provides a genome viewer that enables customizable visualization of all published high-throughput genomic data. The depth and diversity of data sets collected by the Caulobacter community makes CauloBrowser a unique and valuable systems biology resource.

  11. NEO Targets for Biological In Situ Resource Utilization

    Science.gov (United States)

    Grace, J. M.; Ernst, S. M.; Navarrete, J. U.; Gentry, D.

    2014-12-01

    We are investigating a mission architecture concept for low-cost pre-processing of materials on long synodic period asteroids using bioengineered microbes delivered by small spacecraft. Space exploration opportunities, particularly those requiring a human presence, are sharply constrained by the high cost of launching resources such as fuel, construction materials, oxygen, water, and foodstuffs. Near-Earth asteroids (NEAs) have been proposed for supporting a human space presence. However, the combination of high initial investment requirements, delayed potential return, and uncertainty in resource payoff currently prevents their effective utilization.Biomining is the process in which microorganisms perform useful material reduction, sequestration or separation. It is commonly used in terrestrial copper extraction. Compared to physical and chemical methods of extraction it is slow, but very low cost, thus rendering economical even very poor ores. These advantages are potentially extensible to asteroid in situ resource utilization (ISRU).One of the first limiting factors for the use of biology in these environments is temperature. A survey of NEA data was conducted to identify those NEAs whose projected interior temperatures remained within both potential (-5 - 100 ºC) and preferred (15 - 45 ºC) ranges for the minimum projected time per synodic period without exceeding 100 ºC at any point. Approximately 2800 of the 11000 NEAs (25%) are predicted to remain within the potential range for at least 90 days, and 120 (1%) in the preferred range.A second major factor is water availability and stability. We have evaluated a design for a small-spacecraft-based injector which forces low-temperature fluid into the NEA interior, creating potentially habitable microniches. The fluid contains microbes genetically engineered to accelerate the degradation rates of a desired fraction of the native resources, allowing for more efficient material extraction upon a subsequent

  12. Potential of chicken by-products as sources of useful biological resources

    International Nuclear Information System (INIS)

    By-products from different animal sources are currently being utilised for beneficial purposes. Chicken processing plants all over the world generate large amount of solid by-products in form of heads, legs, bones, viscera and feather. These wastes are often processed into livestock feed, fertilizers and pet foods or totally discarded. Inappropriate disposal of these wastes causes environmental pollution, diseases and loss of useful biological resources like protein, enzymes and lipids. Utilisation methods that make use of these biological components for producing value added products rather than the direct use of the actual waste material might be another viable option for dealing with these wastes. This line of thought has consequently led to researches on these wastes as sources of protein hydrolysates, enzymes and polyunsaturated fatty acids. Due to the multi-applications of protein hydrolysates in various branches of science and industry, and the large body of literature reporting the conversion of animal wastes to hydrolysates, a large section of this review was devoted to this subject. Thus, this review reports the known functional and bioactive properties of hydrolysates derived from chicken by-products as well their utilisation as source of peptone in microbiological media. Methods of producing these hydrolysates including their microbiological safety are discussed. Based on the few references available in the literature, the potential of some chicken by-product as sources of proteases and polyunsaturated fatty acids are pointed out along with some other future applications

  13. Potential of chicken by-products as sources of useful biological resources

    Energy Technology Data Exchange (ETDEWEB)

    Lasekan, Adeseye [Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Abu Bakar, Fatimah, E-mail: fatim@putra.upm.edu.my [Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Halal Products Research Institute, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Hashim, Dzulkifly [Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia); Halal Products Research Institute, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor (Malaysia)

    2013-03-15

    By-products from different animal sources are currently being utilised for beneficial purposes. Chicken processing plants all over the world generate large amount of solid by-products in form of heads, legs, bones, viscera and feather. These wastes are often processed into livestock feed, fertilizers and pet foods or totally discarded. Inappropriate disposal of these wastes causes environmental pollution, diseases and loss of useful biological resources like protein, enzymes and lipids. Utilisation methods that make use of these biological components for producing value added products rather than the direct use of the actual waste material might be another viable option for dealing with these wastes. This line of thought has consequently led to researches on these wastes as sources of protein hydrolysates, enzymes and polyunsaturated fatty acids. Due to the multi-applications of protein hydrolysates in various branches of science and industry, and the large body of literature reporting the conversion of animal wastes to hydrolysates, a large section of this review was devoted to this subject. Thus, this review reports the known functional and bioactive properties of hydrolysates derived from chicken by-products as well their utilisation as source of peptone in microbiological media. Methods of producing these hydrolysates including their microbiological safety are discussed. Based on the few references available in the literature, the potential of some chicken by-product as sources of proteases and polyunsaturated fatty acids are pointed out along with some other future applications.

  14. Biological component of the NIMH clinical research branch collaborative program on the psychobiology of depression: I. Background and theoretical considerations.

    Science.gov (United States)

    Maas, J W; Koslow, S H; Davis, J M; Katz, M M; Mendels, J; Robins, E; Stokes, P E; Bowden, C L

    1980-11-01

    There are many reports which suggest that patients with effective illness (mania and/or depression) have abnormalities in the functioning of one or more neurobiological systems. At a conference convened by the Clinical Research Branch, Division of Extramural Research Programs, National Institute of Mental Health, these findings were reviewed and some of the factors impeding movement towards a more complete and integrated view of the functioning of neurobiological systems in patients with mania or depression were identified. As a result, a multi-research centre, collaborative approach to the study of the psychobiology of affective disorders was developed. In this collaborative programme, which has now been underway for several years, the focus has been upon: (a) the assessment of the functioning of several different types of biological systems in the same patient, both before and during treatment; (b) obtaining a reasonably large number of patients and comparison subjects; and (c) the use within and across centres of standardized diagnostic categories and behavioural rating methodologies. In this paper the history, background, and rationale for this collaborative effort are reviewed. Those biological systems chosen for study are noted, and issues such as reliability and validity of diagnoses, measurement of state variables, assessment of change with treatment, and logistical and coordinating problems are discussed.

  15. Biodegradable polymers derived from renewable resources: Highly branched copolymers of itaconic anhydride

    Science.gov (United States)

    Wallach, Joshua Andrew

    In an effort to design cyclic anhydride containing polymers that are derived from renewable resources and have biodegradable characteristics, three copolymer systems using itaconic anhydride have been studied. Two of the systems were copolymers with stearate based monomers; vinyl stearate and stearyl methacrylate, while the third was a copolymer with a methacrylate terminated poly (lactic acid) (PLA) macromonomer. For the stearate systems, stearyl methacrylate showed good copolymerization with equal conversions for both monomers. On the other hand vinyl stearate did not show as good results due to its decreased reactivity, which resulted in a copolymer highly enriched in itaconic anhydride with significant amounts of unreacted vinyl stearate under all copolymer compositions. These differing results were confirmed through analysis of reactivity ratios showing a results that are more favorable for copolymerization for the methacrylate system. Copolymers from both systems showed single melting transitions in a precarious range of 45--50°C arising from the stearyl side groups, though after quenching from the melt this shifted to below room temperature. Anhydride retention was confirmed through structural analysis. Similar to the stearyl methacrylate system, methacrylate terminated PLA macromonomers were copolymerized with itaconic anhydride. PLA's acceptance as a biodegradable material derived from renewable resources, make it a viable choice, with which to design anhydride containing copolymers. Good copolymerization was shown for all compositions studied with retention of the anhydride, though at high itaconic anhydride concentrations conversions were reduced significantly. Copolymers showed glass transition temperatures ranging from 32°C for 85 mole % PLA macromonomer to 73°C for 85 mole % itaconic anhydride. An effort to produce PLA macromonomers through a process of chemical recycling commercial PLA was also undertaken. Promising results were obtained showing

  16. Merging capabilities and livelihoods: analyzing the use of biological resources to improve well-being

    OpenAIRE

    Juri Lienert; Paul Burger

    2015-01-01

    Especially poor people in developing countries depend on biological resources to manage their livelihoods and to generate income. Because these resources are usually public goods, their use is often subjected to what is known as the tragedy of the commons, potentially leading to resource depletion, environmental degradation, and loss of biodiversity, which consequently undermines the availability and capacity of resources to contribute to residents' well-being in the long run. We suggest addr...

  17. Biological and economic foundations of renewable resource exploitation

    International Nuclear Information System (INIS)

    A physiologically based population dynamics model of a renewable resource is used as the basis to develop a model of human harvesting. The model incorporates developing technology and the effects of market forces on the sustainability of common property resources. The bases of the model are analogies between the economics of resource harvesting and allocation by firms and adapted organisms in nature. Specifically, the paper makes the following points: (1) it shows how economic and ecological theories may be unified; (2) it punctuates the importance of time frame in the two systems (evolutionary versus market); (3) it shows, contrary to prevailing economic wisdom, how technological progress may be detrimental to resource preservation; (4) it shows how the anticipated effects of high discount rates on resource use can be catastrophic when synergized by progress in harvesting technology; (5) it suggests that increases in efficiency of utilization of the harvest encourages higher levels of resource exploitation; and (6) it shows the effects of environmental degradation on consumer and resource dynamics. The model leads to global implications on the relationship between economic growth and the ability of modern societies to maintain the environment at a sustainable level

  18. Biomining of regolith simulants for biological in situ resource utilization Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of this proposed research is to advance the development of biological in situ resource utilization for NASA's space exploration programs. We plan to build...

  19. Resource Letter TTSM-1: Teaching thermodynamics and statistical mechanics in introductory physics, chemistry, and biology

    OpenAIRE

    Dreyfus, Benjamin W.; Geller, Benjamin D.; Meltzer, David E.; Sawtelle, Vashti

    2014-01-01

    This Resource Letter draws on discipline-based education research from physics, chemistry, and biology to collect literature on the teaching of thermodynamics and statistical mechanics in the three disciplines. While the overlap among the disciplinary literatures is limited at present, we hope this Resource Letter will spark more interdisciplinary interaction.

  20. Voices long silent were invited to speak: A study of science anxiety in female biology students at a two-year branch campus

    Science.gov (United States)

    Phillips, Deborah J.

    This qualitative study of six female biology students at a two-year branch campus of a major Midwestern university was undertaken to study science anxiety. The study was grounded in feminist theory and addressed the questions of how the students described their science anxiety, what were the possible causes of their science anxiety, what gender issues had impinged upon their lives and education, and what factors had helped them to succeed, despite their science anxiety. Focus group meetings, private interviews, and web-based discussions provided data that described this problem. Data were analyzed for descriptions of science anxiety, possible causes of science anxiety, gender issues, and factors that have encouraged student success. Among the students' varied stories and backgrounds, four commonalities emerged: exposure to some type of significant trauma or obstacles, a lack of rescue for the students as they experienced trauma, a loss of confidence and resulting loss of voice in the students, and elucidation of classroom strategies and other factors that have helped them succeed, despite their science anxiety. Implications arising from this study include the need for a much better understanding of female students attending two-year institutions of higher education, and what measures help them learn. This requires more student-teacher interaction and the use of feminist pedagogy that prioritizes not only best practices, but also justice in the classroom, and opportunities for students to network and share their stories. Other implications include the need for curricular adjustments that would enable the changes in classroom strategies that students need to facilitate learning. Educators and counselors in K--12 also need to be more attentive to student needs and fears, directing them to resources that may smooth their transition to college courses. Implications for future research include the need for a new assessment tool that would test for the kind of data found

  1. Resources

    Science.gov (United States)

    ... palate - resources Colon cancer - resources Cystic fibrosis - resources Depression - resources Diabetes - resources Digestive disease - resources Drug abuse - resources Eating disorders - resources Elder care - resources Epilepsy - resources Family troubles - ...

  2. Use and management of the natural resources of the Colombian Amazon rain forest: a biological approach

    Directory of Open Access Journals (Sweden)

    Angela Yaneth Landínez Torres

    2013-12-01

    Full Text Available This study analyzes the main features associated with biological use practices and management of forest resources in the Colombian Amazon. The theoretical cut proposal contrasts biological level, the forms of appropriation of forest resources in indigenous and urban contexts depending on the importance that such activity involves the establishment of management strategies biodiversity in Colombia. In this way, provides an integrative perspective that will address conflict situations considering environmental factors not only biological but cultural in various scenarios , to give sustenance to the decisions made and provide a reasonable treatment that enables the implementation of environmental regulation mechanisms in especially in areas such as strategic biological Colombian Amazon. Finally, reflect on the importance of facilitating the functional analysis of the connections and interrelationships of ecosystem components, including human communities, sketching involving both biological and social guidelines for sustainable use of biodiversity.

  3. Yucca Mountain biological resources monitoring program; Annual report FY92

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-02-01

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a potential site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities (SCA) do not adversely affect the environment at Yucca Mountain, an environmental program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG&G Energy Measurements, Inc. (EG&G/EM) during fiscal year 1992 (FY92) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support.

  4. Yucca Mountain Biological Resources Monitoring Program; Annual report, FY91

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-01-01

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a possible site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a repository. To ensure that site characterization activities (SCA) do not adversely affect the Yucca Mountain area, an environmental program has been implemented to monitor and mitigate potential impacts and to ensure that activities comply with applicable environmental regulations. This report describes the activities and accomplishments during fiscal year 1991 (FY91) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Activities Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support.

  5. Survey on Agricultural Biological Resources and Traditional Cultural Knowledge of Hani People in Yunnan

    Institute of Scientific and Technical Information of China (English)

    Liqin; ZHANG; Hong; LUO; Wenjie; LONG; Yongtao; LEI; Qing; CAI; Mei; LAN; Li; ZHONG

    2015-01-01

    In 2007- 2008,a systematic survey,collection and arrangement was carried out for agricultural biological resources and traditional cultural knowledge of Hani People in 8 counties,15 towns,and 23 village committees of Yunnan Province. A total of 299 samples were obtained about agricultural biological resources related to production and living of Hani People. According to purpose of utilization,samples were divided into grain crops,medicinal plants,vegetables,fruit trees,and oil crops,taking up 48. 2%,21. 7%,18. 4%,7. 7%,and 2. 0% of the samples respectively. The survey indicated that planting industry and breeding industry take up the dominant role in rural social economy of Hani People,so agricultural biological resources are the fundamental means of production maintaining rural social development of Hani People.The current situation of agricultural biological resources of Hani People in Yunnan,reasons for growth and decline were analyzed,and the utilization,protection and development of agricultural biological resources were discussed.

  6. iTools: a framework for classification, categorization and integration of computational biology resources.

    Directory of Open Access Journals (Sweden)

    Ivo D Dinov

    Full Text Available The advancement of the computational biology field hinges on progress in three fundamental directions--the development of new computational algorithms, the availability of informatics resource management infrastructures and the capability of tools to interoperate and synergize. There is an explosion in algorithms and tools for computational biology, which makes it difficult for biologists to find, compare and integrate such resources. We describe a new infrastructure, iTools, for managing the query, traversal and comparison of diverse computational biology resources. Specifically, iTools stores information about three types of resources--data, software tools and web-services. The iTools design, implementation and resource meta-data content reflect the broad research, computational, applied and scientific expertise available at the seven National Centers for Biomedical Computing. iTools provides a system for classification, categorization and integration of different computational biology resources across space-and-time scales, biomedical problems, computational infrastructures and mathematical foundations. A large number of resources are already iTools-accessible to the community and this infrastructure is rapidly growing. iTools includes human and machine interfaces to its resource meta-data repository. Investigators or computer programs may utilize these interfaces to search, compare, expand, revise and mine meta-data descriptions of existent computational biology resources. We propose two ways to browse and display the iTools dynamic collection of resources. The first one is based on an ontology of computational biology resources, and the second one is derived from hyperbolic projections of manifolds or complex structures onto planar discs. iTools is an open source project both in terms of the source code development as well as its meta-data content. iTools employs a decentralized, portable, scalable and lightweight framework for long

  7. iTools: a framework for classification, categorization and integration of computational biology resources.

    Science.gov (United States)

    Dinov, Ivo D; Rubin, Daniel; Lorensen, William; Dugan, Jonathan; Ma, Jeff; Murphy, Shawn; Kirschner, Beth; Bug, William; Sherman, Michael; Floratos, Aris; Kennedy, David; Jagadish, H V; Schmidt, Jeanette; Athey, Brian; Califano, Andrea; Musen, Mark; Altman, Russ; Kikinis, Ron; Kohane, Isaac; Delp, Scott; Parker, D Stott; Toga, Arthur W

    2008-05-28

    The advancement of the computational biology field hinges on progress in three fundamental directions--the development of new computational algorithms, the availability of informatics resource management infrastructures and the capability of tools to interoperate and synergize. There is an explosion in algorithms and tools for computational biology, which makes it difficult for biologists to find, compare and integrate such resources. We describe a new infrastructure, iTools, for managing the query, traversal and comparison of diverse computational biology resources. Specifically, iTools stores information about three types of resources--data, software tools and web-services. The iTools design, implementation and resource meta-data content reflect the broad research, computational, applied and scientific expertise available at the seven National Centers for Biomedical Computing. iTools provides a system for classification, categorization and integration of different computational biology resources across space-and-time scales, biomedical problems, computational infrastructures and mathematical foundations. A large number of resources are already iTools-accessible to the community and this infrastructure is rapidly growing. iTools includes human and machine interfaces to its resource meta-data repository. Investigators or computer programs may utilize these interfaces to search, compare, expand, revise and mine meta-data descriptions of existent computational biology resources. We propose two ways to browse and display the iTools dynamic collection of resources. The first one is based on an ontology of computational biology resources, and the second one is derived from hyperbolic projections of manifolds or complex structures onto planar discs. iTools is an open source project both in terms of the source code development as well as its meta-data content. iTools employs a decentralized, portable, scalable and lightweight framework for long-term resource management

  8. Investment into the future of microbial resources: culture collection funding models and BRC business plans for biological resource centres

    OpenAIRE

    Smith, David; McCluskey, Kevin; Stackebrandt, Erko

    2014-01-01

    Through their long history of public service, diverse microbial Biological Resource Centres (mBRCs) have made myriad contributions to society and science. They have enabled the maintenance of specimens isolated before antibiotics, made available strains showing the development and change of pathogenicity toward animals, humans and plants, and have maintained and provided reference strains to ensure quality and reproducibility of science. However, this has not been achieved without considerabl...

  9. Resource Letter BELFEF-1: Biological effects of low-frequency electromagnetic fields

    Science.gov (United States)

    Hafemeister, David

    1996-08-01

    This Resource Letter provides a guide to the literature on the interaction of extremely low-frequency electromagnetic field (ELF/EMF) interactions with biological matter, and on the possibility that such interactions could have a harmful effect on human health. Journal articles and books are cited for the following topics: ELF/EMF theoretical interactions with biological cells, organs and organisms, magnetic dipole interactions, sensing by animals, biomedical-biophysical experiments, epidemiology, and litigation-mitigation risk issues.

  10. Building Consensus in Science: Resources for Intertextual Dialog in Biology Research Articles

    Science.gov (United States)

    Martinez, Iliana A.

    2008-01-01

    This paper reports on the way article writers bring prior texts into biology research articles. It studies the functional moves in which citations occur and their formal features, providing a better understanding of the linguistic resources that are used to construct intertextuality in science. The results show the functions of citations were…

  11. Chemical structure and biological activity of a highly branched (1 → 3,1 → 6)-β-D-glucan from Isochrysis galbana.

    Science.gov (United States)

    Sadovskaya, Irina; Souissi, Anissa; Souissi, Sami; Grard, Thierry; Lencel, Philippe; Greene, Catherine M; Duin, Sarah; Dmitrenok, Pavel S; Chizhov, Alexander O; Shashkov, Alexander S; Usov, Anatolii I

    2014-10-13

    A highly branched (1 → 3,1 → 6)-β-D-glucan was isolated from the microalga Isochrysis galbana Parke (Isochrysidales, Haptophyta). The polysaccharide structure was analyzed by methylation and Smith degradation, as well as by ESI and MALDI TOF mass spectrometry and NMR spectroscopy. The glucan was shown to contain a (1 → 6)-linked backbone, where every residue is substituted at position 3 by Glc, which in turn may be substituted at C-6 by a single Glc or by rather short (up to tetrasaccharide) oligosaccharide chains. All the 3-linked Glc residues are present in these side chains. In the biological activity experiments it was demonstrated that the polysaccharide directly inhibits the proliferation of U937 human leukemic monocyte lymphoma cells and therefore has potential anti-tumor activity.

  12. Fort Collins Science Center Ecosystem Dynamics Branch

    Science.gov (United States)

    Wilson, Jim; Melcher, C.; Bowen, Z.

    2009-01-01

    Complex natural resource issues require understanding a web of interactions among ecosystem components that are (1) interdisciplinary, encompassing physical, chemical, and biological processes; (2) spatially complex, involving movements of animals, water, and airborne materials across a range of landscapes and jurisdictions; and (3) temporally complex, occurring over days, weeks, or years, sometimes involving response lags to alteration or exhibiting large natural variation. Scientists in the Ecosystem Dynamics Branch of the U.S. Geological Survey, Fort Collins Science Center, investigate a diversity of these complex natural resource questions at the landscape and systems levels. This Fact Sheet describes the work of the Ecosystems Dynamics Branch, which is focused on energy and land use, climate change and long-term integrated assessments, herbivore-ecosystem interactions, fire and post-fire restoration, and environmental flows and river restoration.

  13. 保护生物学一新分支学科——保护遗传学%NEW BRANCH OF CONSERVATION BIOLOGY:CONSERVATION GENETICS

    Institute of Scientific and Technical Information of China (English)

    李明; 魏辅文; 冯祚建; 谢菁; 方盛国; 张志和

    2001-01-01

    To understand human effects on biodiversity and prevent species from extinction are two primary aims of conservation biology.With environmental deterioration,rapid development of molecular genetics and pervasion between conservation biology and molecular genetics,studies on biodiversity conservation lead to appearance of new branch of conservation biology,the conservation genetics.Conservation genetics mainly studies conservation of genetic diversity and keeps evolutionary potential of species.It has been hotspot of conservation biology in the world,but just starts in China.Hereby,we introduce its appearance,development,and main research areas so as to impel this kind of research in China.%研究人类对生物多样性的影响以及防止物种灭绝是保护生物学的两个主要目的。随着环境日益恶化、分子遗传学的迅速发展以及保护生物学和分子遗传学的不断相互渗透,孕育和产生了一全新的分支学科——保护遗传学。保护遗传学是保护生物学研究中的一个核心部分,主要研究濒危物种的遗传多样性和保持物种的进化潜力。目前保护遗传学已成为国际上的一个研究热点,但在我国才刚刚起步。为此,本文就保护遗传学的产生和发展及其研究内容和意义作一简要介绍,以推动我国在该方面的研究。

  14. The role of informatics in the coordinated management of biological resources collections.

    Science.gov (United States)

    Romano, Paolo; Kracht, Manfred; Manniello, Maria Assunta; Stegehuis, Gerrit; Fritze, Dagmar

    2005-01-01

    The term 'biological resources' is applied to the living biological material collected, held and catalogued in culture collections: bacterial and fungal cultures; animal, human and plant cells; viruses; and isolated genetic material. A wealth of information on these materials has been accumulated in culture collections, and most of this information is accessible. Digitalisation of data has reached a high level; however, information is still dispersed. Individual and coordinated approaches have been initiated to improve accessibility of biological resource centres, their holdings and related information through the Internet. These approaches cover subjects such as standardisation of data handling and data accessibility, and standardisation and quality control of laboratory procedures. This article reviews some of the most important initiatives implemented so far, as well as the most recent achievements. It also discusses the possible improvements that could be achieved by adopting new communication standards and technologies, such as web services, in view of a deeper and more fruitful integration of biological resources information in the bioinformatics network environment. PMID:16231959

  15. Evaluation of a fungal collection as certified reference material producer and as a biological resource center.

    Science.gov (United States)

    Forti, Tatiana; Souto, Aline da S S; do Nascimento, Carlos Roberto S; Nishikawa, Marilia M; Hubner, Marise T W; Sabagh, Fernanda P; Temporal, Rosane Maria; Rodrigues, Janaína M; da Silva, Manuela

    2016-01-01

    Considering the absence of standards for culture collections and more specifically for biological resource centers in the world, in addition to the absence of certified biological material in Brazil, this study aimed to evaluate a Fungal Collection from Fiocruz, as a producer of certified reference material and as Biological Resource Center (BRC). For this evaluation, a checklist based on the requirements of ABNT ISO GUIA34:2012 correlated with the ABNT NBR ISO/IEC17025:2005, was designed and applied. Complementing the implementation of the checklist, an internal audit was performed. An evaluation of this Collection as a BRC was also conducted following the requirements of the NIT-DICLA-061, the Brazilian internal standard from Inmetro, based on ABNT NBR ISO/IEC 17025:2005, ABNT ISO GUIA 34:2012 and OECD Best Practice Guidelines for BRCs. This was the first time that the NIT DICLA-061 was applied in a culture collection during an internal audit. The assessments enabled the proposal for the adequacy of this Collection to assure the implementation of the management system for their future accreditation by Inmetro as a certified reference material producer as well as its future accreditation as a Biological Resource Center according to the NIT-DICLA-061. PMID:26991280

  16. Evaluation of a fungal collection as certified reference material producer and as a biological resource center

    Directory of Open Access Journals (Sweden)

    Tatiana Forti

    2016-06-01

    Full Text Available Abstract Considering the absence of standards for culture collections and more specifically for biological resource centers in the world, in addition to the absence of certified biological material in Brazil, this study aimed to evaluate a Fungal Collection from Fiocruz, as a producer of certified reference material and as Biological Resource Center (BRC. For this evaluation, a checklist based on the requirements of ABNT ISO GUIA34:2012 correlated with the ABNT NBR ISO/IEC17025:2005, was designed and applied. Complementing the implementation of the checklist, an internal audit was performed. An evaluation of this Collection as a BRC was also conducted following the requirements of the NIT-DICLA-061, the Brazilian internal standard from Inmetro, based on ABNT NBR ISO/IEC 17025:2005, ABNT ISO GUIA 34:2012 and OECD Best Practice Guidelines for BRCs. This was the first time that the NIT DICLA-061 was applied in a culture collection during an internal audit. The assessments enabled the proposal for the adequacy of this Collection to assure the implementation of the management system for their future accreditation by Inmetro as a certified reference material producer as well as its future accreditation as a Biological Resource Center according to the NIT-DICLA-061.

  17. Access to genetic resources in indigenous peoples and the Convention on Biological Diversity

    Directory of Open Access Journals (Sweden)

    Diana Rocío Bernal Camargo

    2013-06-01

    Full Text Available After the Convention on Biological Diversity a deepening debate is taking place concerning the protection of genetic resources and traditional knowledge of indigenous peoples, which involves a discussion about the application of biotechnology and its impact on the protection of life and environment, and an analysis of the participation of these in the process of developing strategies to protect their resources and traditional knowledge, which gives rise to legal pluralism from the development of the different Conferences of the Parties, which today allows for a more comprehensive regulatory framework and a possibility of its strengthening.

  18. Investment into the future of microbial resources: culture collection funding models and BRC business plans for biological resource centres.

    Science.gov (United States)

    Smith, David; McCluskey, Kevin; Stackebrandt, Erko

    2014-01-01

    Through their long history of public service, diverse microbial Biological Resource Centres (mBRCs) have made myriad contributions to society and science. They have enabled the maintenance of specimens isolated before antibiotics, made available strains showing the development and change of pathogenicity toward animals, humans and plants, and have maintained and provided reference strains to ensure quality and reproducibility of science. However, this has not been achieved without considerable financial commitment. Different collections have unique histories and their support is often tied to their origins. However many collections have grown to serve large constituencies and need to develop novel funding mechanisms. Moreover, several international initiatives have described mBRCs as a factor in economic development and have led to the increased professionalism among mBRCs. PMID:24570852

  19. Investment into the future of microbial resources: culture collection funding models and BRC business plans for biological resource centres.

    Science.gov (United States)

    Smith, David; McCluskey, Kevin; Stackebrandt, Erko

    2014-01-01

    Through their long history of public service, diverse microbial Biological Resource Centres (mBRCs) have made myriad contributions to society and science. They have enabled the maintenance of specimens isolated before antibiotics, made available strains showing the development and change of pathogenicity toward animals, humans and plants, and have maintained and provided reference strains to ensure quality and reproducibility of science. However, this has not been achieved without considerable financial commitment. Different collections have unique histories and their support is often tied to their origins. However many collections have grown to serve large constituencies and need to develop novel funding mechanisms. Moreover, several international initiatives have described mBRCs as a factor in economic development and have led to the increased professionalism among mBRCs.

  20. Engineering assessment and feasibility study of Chattanooga Shale as a future source of uranium. [Preliminary mining; data on soils, meteorology, water resources, and biological resources

    Energy Technology Data Exchange (ETDEWEB)

    1978-06-01

    This volume contains five appendixes: Chattanooga Shale preliminary mining study, soils data, meteorologic data, water resources data, and biological resource data. The area around DeKalb County in Tennessee is the most likely site for commercial development for recovery of uranium. (DLC)

  1. Branching out

    CERN Document Server

    Biggins, J D

    2010-01-01

    Results on the behaviour of the rightmost particle in the $n$th generation in the branching random walk are reviewed and the phenomenon of anomalous spreading speeds, noticed recently in related deterministic models, is considered. The relationship between such results and certain coupled reaction-diffusion equations is indicated.

  2. Biological ensemble modeling to evaluate potential futures of living marine resources

    DEFF Research Database (Denmark)

    Gårdmark, Anna; Lindegren, Martin; Neuenfeldt, Stefan;

    2013-01-01

    Natural resource management requires approaches to understand and handle sources of uncertainty in future responses of complex systems to human activities. Here we present one such approach, the “biological ensemble modeling approach,” using the Eastern Baltic cod (Gadus morhua callarias) as an...... single-species to food web models. These models were analyzed using the “biological ensemble modeling approach” by which we (1) identified a key ecological mechanism explaining the differences in simulated cod responses between models, (2) disentangled the uncertainty caused by differences in ecological...... model assumptions from the statistical uncertainty of future climate, and (3) identified results common for the whole model ensemble. Species interactions greatly influenced the simulated response of cod to fishing and climate, as well as the degree to which the statistical uncertainty of climate...

  3. Form and function: Perspectives on structural biology and resources for the future

    International Nuclear Information System (INIS)

    The purpose of this study is largely to explore and expand on the thesis that biological structures and their functions are suited to. Form indeed follows function and if we are to understand the workings of a living system, with all that such an understanding promises, we must first seek to describe the structure of its parts. Descriptions of a few achievements of structural biology lay the groundwork, but the substance of this booklet is a discussion of important questions yet unanswered and opportunities just beyond our grasp. The concluding pages then outline a course of action in which the Department of Energy would exercise its responsibility to develop the major resources needed to extend our reach and to answer some of those unanswered questions. 22 figs

  4. Form and function: Perspectives on structural biology and resources for the future

    Energy Technology Data Exchange (ETDEWEB)

    Vaughan, D. (ed.)

    1990-12-01

    The purpose of this study is largely to explore and expand on the thesis that biological structures and their functions are suited to. Form indeed follows function and if we are to understand the workings of a living system, with all that such an understanding promises, we must first seek to describe the structure of its parts. Descriptions of a few achievements of structural biology lay the groundwork, but the substance of this booklet is a discussion of important questions yet unanswered and opportunities just beyond our grasp. The concluding pages then outline a course of action in which the Department of Energy would exercise its responsibility to develop the major resources needed to extend our reach and to answer some of those unanswered questions. 22 figs.

  5. A Preliminary Study of the Microbial Resources and Their Biological Activities of the East China Sea

    Directory of Open Access Journals (Sweden)

    Xiaoling Lu

    2011-01-01

    Full Text Available East China Sea is one of the four sea areas in China, which possesses peculiar ecological environment and many kinds of living creatures, especially the microorganisms. We established the East China Sea microorganism library (during 2006–2010 for the first time, which stored about 30000 strains that covered most kinds of the species. In this paper, 395 pure strains of East China Sea microorganism library which belong to 33 different genera were mainly introduced. Sulfitobacter, Halomonas, Bacillus, Pseudoalteromonas, and Idiomarina were the most dominant species. On the large-scale biological activity screening of the 395 strains, 100 strains possess different biological activities based on different screening models, of which 11.4% strains have antibacterial activities, 15.9% have cytotoxicity activities, and 6.1% have antioxidation activities. Besides, the secondary metabolites of 6 strains with strong biological activities were studied systematically; diketopiperazines and macrocyclic lactones are the active secondary metabolites. The species and the biological activity of microorganisms diversity, the abundant structure type of the secondary metabolites, and their bioactivities all indicate that East China Sea is a potent marine microorganisms-derived developing resource for drug discovery.

  6. Merging capabilities and livelihoods: analyzing the use of biological resources to improve well-being

    Directory of Open Access Journals (Sweden)

    Juri Lienert

    2015-06-01

    Full Text Available Especially poor people in developing countries depend on biological resources to manage their livelihoods and to generate income. Because these resources are usually public goods, their use is often subjected to what is known as the tragedy of the commons, potentially leading to resource depletion, environmental degradation, and loss of biodiversity, which consequently undermines the availability and capacity of resources to contribute to residents' well-being in the long run. We suggest addressing this typical sustainability issue from a new angle. Against the backdrop of identifiable shortcomings within two popular analytic approaches, the capability approach (CA and the sustainable livelihood approach (SLA, we argue for an improved sustainability framework for analyzing the issue in question. Although we view the CA as encompassing our core ideas regarding human well-being, we propose to enrich it by merging it with the SLA to more adequately include social and environmental capital. To test the framework's usefulness, we apply it to a case study on the use of medicinal and aromatic plants in the rural livelihood context of Nepal. Thereby, we reveal not only that the creation of capabilities is strongly dependent on the set of capital assets available, particularly in the form of natural capital, but also that the framework provides new perspectives: What matters is developing livelihood strategies that increase people's opportunity spaces rather than focusing only on those that compensate for missing capabilities or enable people to cope with shocks and vulnerability.

  7. Ecological Footprint of Biological Resource Consumption in a Typical Area of the Green for Grain Project in Northwestern China

    Directory of Open Access Journals (Sweden)

    Jie Hu

    2015-01-01

    Full Text Available Following the implementation of the Green for Grain Project in 2000 in Guyuan, China, the decrease in cultivated land and subsequent increase in forest and grassland pose substantial challenges for the supply of biological products. Whether the current biologically productive land-use patterns in Guyuan satisfy the biological product requirements for local people is an urgent problem. In this study, the ecological footprints of biological resource consumption in Guyuan were calculated and analyzed based on the ‘City Hectare’ Ecological Footprint (EF Method. The EFs of different types of biological resource products consumed from different types of biologically productive land were then analyzed. In addition, the EFs of various biological resource products before and after the implementation of the Green for Grain Project (1998 and 2012 were assessed. The actual EF and bio-capacity (BC were compared, and differences in the EF and BC for different types of biologically productive lands before and after the project were analyzed. The results showed that the EF of Guyuan’s biological resource products was 0.65866 ha/cap, with an EF outflow and EF inflow of 0.2280 ha/cap and 0.0951 ha/cap, respectively. The per capita EF of Guyuan significantly decreased after the project, as did the ecological deficit. Whereas the cultivated land showed a deficit, grasslands were characterized by ecological surplus. The total EF of living resource consumption in Guyuan was 810,941 ha, and the total BC was 768,065 ha. In additional to current biological production areas, approximately 42,876 ha will be needed to satisfy the demands of Guyuan’s people. Cultivated land is the main type of biologically productive land that is needed.

  8. UNDERGRADUATE EDUCATION IN THE BIOLOGICAL SCIENCES FOR STUDENTS IN AGRICULTURE AND NATURAL RESOURCES, PROCEEDINGS OF A CONFERENCE.

    Science.gov (United States)

    National Academy of Sciences - National Research Council, Washington, DC.

    REPORTED ARE THE PROCEEDINGS OF A 1966 CONFERENCE WHICH DEALT WITH UNDERGRADUATE EDUCATIONAL NEEDS FOR STUDENTS IN AGRICULTURE AND NATURAL RESOURCES. THE 167 EDUCATORS (MOSTLY DEANS AND DIRECTORS OF RESIDENT INSTRUCTION) WHO PARTICIPATED IN THE CONFERENCE REPRESENTED AGRICULTURE, RENEWABLE NATURAL RESOURCES, THE BIOLOGICAL SCIENCES, AND…

  9. Ecological effects of contaminants in McCoy Branch, 1989-1990

    Energy Technology Data Exchange (ETDEWEB)

    Ryon, M.G. [ed.

    1992-01-01

    The 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act (RCRA) required assessment of all current and former solid waste management units. Such a RCRA Facility Investigation (RFI) was required of the Y-12 Plant for their Filled Coal Ash Pond on McCoy Branch. Because the disposal of coal ash in the ash pond, McCoy Branch, and Rogers Quarry was not consistent with the Tennessee Water Quality Act, several remediation steps were implemented or planned for McCoy Branch to address disposal problems. The McCoy Branch RFI plan included provisions for biological monitoring of the McCoy Branch watershed. The objectives of the biological monitoring were to: (1) document changes in biological quality of McCoy Branch after completion of a pipeline and after termination of all discharges to Rogers Quarry, (2) provide guidance on the need for additional remediation, and (3) evaluate the effectiveness of implemented remedial actions. The data from the biological monitoring program will also determine if the classified uses, as identified by the State of Tennessee, of McCoy Branch are being protected and maintained. This report discusses results from toxicity monitoring of snails fish community assessment, and a Benthic macroinvertebrate community assessment.

  10. Ecological effects of contaminants in McCoy Branch, 1991--1993

    Energy Technology Data Exchange (ETDEWEB)

    Ryon, M.G. [ed.

    1996-09-01

    The 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act (RCRA) required assessment of all current and former solid waste management units. Following guidelines under RCRA and the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), a remedial investigation (RI) was required of the Y-12 Plant for their filled coal ash pond (FCAP) and associated areas on McCoy Branch. The RI process was initiated and assessments were presented. Because the disposal of coal ash in the ash pond, McCoy Branch, and Rogers Quarry was not consistent with the Tennessee Water Quality Act, several remediation steps were implemented between 1986 and 1994 for McCoy Branch to address disposal problems. The required ecological risk assessments of McCoy Branch watershed included provisions for biological monitoring of the watershed. The objectives of the biological monitoring were to (1) document changes in biological quality of McCoy Branch after completion of a pipeline bypassing upper McCoy Branch and further, after termination of all discharges to Rogers Quarry, (2) provide guidance on the need for additional remediation, and (3) evaluate the effectiveness of implemented remedial actions. The data from the biological monitoring program may also determine whether the goals of protection of human health and the environment of McCoy Branch are being accomplished.

  11. Modeling branching in cereals

    OpenAIRE

    Jochem B. Evers; Vos, Jan

    2013-01-01

    Cereals and grasses adapt their structural development to environmental conditions and the resources available. The primary adaptive response is a variable degree of branching, called tillering in cereals. Especially for heterogeneous plant configurations the degree of tillering varies per plant. Functional–structural plant modeling (FSPM) is a modeling approach allowing simulation of the architectural development of individual plants, culminating in the emergent behavior at the canopy level....

  12. Research progress in the phytochemistry and biology of Ilex pharmaceutical resources

    Directory of Open Access Journals (Sweden)

    Dacheng Hao

    2013-02-01

    Full Text Available Ilex is a botanical source for various health-promoting and pharmaceutically active compounds that have been used in traditional Chinese medicine and food for thousands of years. Increasing interest in Ilex pharmaceutical and food resources has led to additional discoveries of terpenoids, saponins, polyphenols (especially flavonoids, glycosides, and many other compounds in various Ilex species, and to investigation of their chemotaxonomy, molecular phylogeny and pharmacology. In continuation of our studies on Ilex pharmacology and phylogeny, we review the phytochemistry, chemotaxonomy, molecular biology and phylogeny of Ilex species and their relevance to health-promotion and therapeutic efficacy. The similarity and dissimilarity between Ilex paraguariensis, the source plant of mate tea, and the source plants of large-leaved Kudingcha (e.g., Ilex kudingcha and Ilex latifolia are discussed. It is essential to utilize emerging technologies in non-Camellia tea studies to promote the sustainable utilization of Ilex resources and the identification and development of novel compounds with potential health and clinical utility. Systems biology and “-omics” technologies will play an increasingly important role in pharmaceutical and food research on the bioactive compounds of Ilex species.

  13. Code of Conduct on Biosecurity for Biological Resource Centres: procedural implementation.

    Science.gov (United States)

    Rohde, Christine; Smith, David; Martin, Dunja; Fritze, Dagmar; Stalpers, Joost

    2013-07-01

    A globally applicable code of conduct specifically dedicated to biosecurity has been developed together with guidance for its procedural implementation. This is to address the regulations governing potential dual-use of biological materials, associated information and technologies, and reduce the potential for their malicious use. Scientists researching and exchanging micro-organisms have a responsibility to prevent misuse of the inherently dangerous ones, that is, those possessing characters such as pathogenicity or toxin production. The code of conduct presented here is based on best practice principles for scientists and their institutions working with biological resources with a specific focus on micro-organisms. It aims to raise awareness of regulatory needs and to protect researchers, their facilities and stakeholders. It reflects global activities in this area in response to legislation such as that in the USA, the PATRIOT Act of 2001, Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act of 2001; the Anti-Terrorism Crime and Security Act 2001 and subsequent amendments in the UK; the EU Dual-Use Regulation; and the recommendations of the Organization for Economic Co-operation and Development (OECD), under their Biological Resource Centre (BRC) Initiative at the beginning of the millennium (OECD, 2001). Two project consortia with international partners came together with experts in the field to draw up a Code of Conduct on Biosecurity for BRCs to ensure that culture collections and microbiologists in general worked in a way that met the requirements of such legislation. A BRC is the modern day culture collection that adds value to its holdings and implements common best practice in the collection and supply of strains for research and development. This code of conduct specifically addresses the work of public service culture collections and describes the issues of importance and the controls or

  14. Expanding comparative-advantage biological market models: contingency of mutualism on partners' resource requirements and acquisition trade-offs.

    Science.gov (United States)

    Hoeksema, Jason D; Schwartz, Mark W

    2003-05-01

    We expand the comparative-advantage biological market-modelling framework to show how differences between partners, both in their abilities to acquire two resources and in their requirements for those resources, can affect the net benefit of participating in interspecific resource exchange. In addition, the benefits derived from resource trading depend strongly on the nature of the trade-off between the acquisition of one resource and the acquisition of another, described here by the shape (linear, convex or concave) of the resource acquisition constraints of the individuals involved. Combined with previous results, these analyses provide a suite of predictions about whether or not resource exchange is beneficial for two heterospecific individuals relative to a strategy of non-interaction. The benefit derived from resource exchange depends on three factors: (i) relative differences between the partners in their resource acquisition abilities; (ii) relative differences between the partners in their resource requirements; and (iii) variation in the shape of resource acquisition trade-offs. We find that such an explicit consideration of resource requirements and acquisition abilities can provide useful and sometimes non-intuitive predictions about the benefits of resource exchange, and also which resources should be traded by which species.

  15. Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources.

    Science.gov (United States)

    Waagmeester, Andra; Kutmon, Martina; Riutta, Anders; Miller, Ryan; Willighagen, Egon L; Evelo, Chris T; Pico, Alexander R

    2016-06-01

    The diversity of online resources storing biological data in different formats provides a challenge for bioinformaticians to integrate and analyse their biological data. The semantic web provides a standard to facilitate knowledge integration using statements built as triples describing a relation between two objects. WikiPathways, an online collaborative pathway resource, is now available in the semantic web through a SPARQL endpoint at http://sparql.wikipathways.org. Having biological pathways in the semantic web allows rapid integration with data from other resources that contain information about elements present in pathways using SPARQL queries. In order to convert WikiPathways content into meaningful triples we developed two new vocabularies that capture the graphical representation and the pathway logic, respectively. Each gene, protein, and metabolite in a given pathway is defined with a standard set of identifiers to support linking to several other biological resources in the semantic web. WikiPathways triples were loaded into the Open PHACTS discovery platform and are available through its Web API (https://dev.openphacts.org/docs) to be used in various tools for drug development. We combined various semantic web resources with the newly converted WikiPathways content using a variety of SPARQL query types and third-party resources, such as the Open PHACTS API. The ability to use pathway information to form new links across diverse biological data highlights the utility of integrating WikiPathways in the semantic web. PMID:27336457

  16. Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources

    Science.gov (United States)

    Waagmeester, Andra; Pico, Alexander R.

    2016-01-01

    The diversity of online resources storing biological data in different formats provides a challenge for bioinformaticians to integrate and analyse their biological data. The semantic web provides a standard to facilitate knowledge integration using statements built as triples describing a relation between two objects. WikiPathways, an online collaborative pathway resource, is now available in the semantic web through a SPARQL endpoint at http://sparql.wikipathways.org. Having biological pathways in the semantic web allows rapid integration with data from other resources that contain information about elements present in pathways using SPARQL queries. In order to convert WikiPathways content into meaningful triples we developed two new vocabularies that capture the graphical representation and the pathway logic, respectively. Each gene, protein, and metabolite in a given pathway is defined with a standard set of identifiers to support linking to several other biological resources in the semantic web. WikiPathways triples were loaded into the Open PHACTS discovery platform and are available through its Web API (https://dev.openphacts.org/docs) to be used in various tools for drug development. We combined various semantic web resources with the newly converted WikiPathways content using a variety of SPARQL query types and third-party resources, such as the Open PHACTS API. The ability to use pathway information to form new links across diverse biological data highlights the utility of integrating WikiPathways in the semantic web. PMID:27336457

  17. Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing.

    Science.gov (United States)

    Tacutu, Robi; Craig, Thomas; Budovsky, Arie; Wuttke, Daniel; Lehmann, Gilad; Taranukha, Dmitri; Costa, Joana; Fraifeld, Vadim E; de Magalhães, João Pedro

    2013-01-01

    The Human Ageing Genomic Resources (HAGR, http://genomics.senescence.info) is a freely available online collection of research databases and tools for the biology and genetics of ageing. HAGR features now several databases with high-quality manually curated data: (i) GenAge, a database of genes associated with ageing in humans and model organisms; (ii) AnAge, an extensive collection of longevity records and complementary traits for >4000 vertebrate species; and (iii) GenDR, a newly incorporated database, containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction. Since its creation about 10 years ago, major efforts have been undertaken to maintain the quality of data in HAGR, while further continuing to develop, improve and extend it. This article briefly describes the content of HAGR and details the major updates since its previous publications, in terms of both structure and content. The completely redesigned interface, more intuitive and more integrative of HAGR resources, is also presented. Altogether, we hope that through its improvements, the current version of HAGR will continue to provide users with the most comprehensive and accessible resources available today in the field of biogerontology.

  18. Fluid Flow at Branching Junctions

    OpenAIRE

    Sochi, Taha

    2013-01-01

    The flow of fluids at branching junctions plays important kinematic and dynamic roles in most biological and industrial flow systems. The present paper highlights some key issues related to the flow of fluids at these junctions with special emphasis on the biological flow networks particularly blood transportation vasculature.

  19. A Review of the Biology, Culture, Exploitation and Utilization Potentials Seaweed Resources: Case Study in Nigeria

    Directory of Open Access Journals (Sweden)

    J.F.N. Abowei

    2011-04-01

    Full Text Available The importance of seaweeds cuts across various environmental, ecologic, socio-economic benefits and services as food for man, in the phycocolloids and expanding phycosupplement industries, as sink for excess carbon dioxide and excess nutrients; for sustainable energy generation and as fossil fuel substitutes. In view of this, seaweeds could become an important economic niche for Asian(Japan and China, Nigeria and other coastal African countries provided adequate research is undertaken in studying their diversity, biochemical compositions and potentials for culture in order to harness the numerous opportunities which can be derived. This article reviews the biological characteristics, potential products and uses, culture and transplantation, distribution and biodiversity, status of exploitation and conservation. Benefits of developing seaweed sector and challenges to the exploitation, culture and utilization of potential seaweed resources, aimed at unveiling the potentials in the utilization of seaweed in Nigeria and other interested countries.

  20. Um algoritmo branch-and-bound para o problema de programação de projetos com custo de disponibilidade de recursos e múltiplos modos A branch-and-bound algorithm for the resource constrained project scheduling problem with resource availability cost and multiple modes

    Directory of Open Access Journals (Sweden)

    Denise Sato Yamashita

    2007-12-01

    Full Text Available Em um estudo anterior (YAMASHITA; MORABITO, 2007a, foi proposto um algoritmo exato para resolver o problema de programação de projetos com custo de disponibilidade de recursos, considerando múltiplos modos de execução para as atividades. O algoritmo é uma adaptação de outro algoritmo exato da literatura para o caso particular do problema em que só existe um modo de executar as atividades. No presente estudo, é proposto um novo algoritmo exato baseado no método branch-and-bound para tratar do problema com múltiplos modos de execução. Como o problema é NP-difícil, o algoritmo é viável computacionalmente apenas para resolver exemplares de tamanho moderado. Diversos testes computacionais utilizando o programa gerador Progen da literatura foram realizados para comparar o desempenho do algoritmo proposto com o algoritmo anterior e também com o aplicativo CPLEX. Os resultados obtidos mostram que a versão atual do algoritmo é competitiva com os outros métodos, e estimulam a pesquisa e o desenvolvimento de versões mais elaboradas deste algoritmo.In a recent study (YAMASHITA; MORABITO, 2007a, it was proposed an exact algorithm to solve problems of resource-constrained project scheduling with resource availability costs under multiple modes of execution. That algorithm is an adaptation of another exact algorithm recorded in the literature for the particular case where there is only a single mode for executing the tasks. In the present study, we propose a new exact algorithm based on the branch and bound method to deal with multiple performing modes problem. Since the problem is NP-hard, the algorithm is computationally viable only for problems of moderate size. Numerous computational tests using the generator ProGen were run to compare the performance of the proposed algorithm with the former algorithm and with the CPLEX software. The results show that the proposed version of the algorithm is competitive with the other methods and

  1. The Pig PeptideAtlas: A resource for systems biology in animal production and biomedicine.

    Science.gov (United States)

    Hesselager, Marianne O; Codrea, Marius C; Sun, Zhi; Deutsch, Eric W; Bennike, Tue B; Stensballe, Allan; Bundgaard, Louise; Moritz, Robert L; Bendixen, Emøke

    2016-02-01

    Biological research of Sus scrofa, the domestic pig, is of immediate relevance for food production sciences, and for developing pig as a model organism for human biomedical research. Publicly available data repositories play a fundamental role for all biological sciences, and protein data repositories are in particular essential for the successful development of new proteomic methods. Cumulative proteome data repositories, including the PeptideAtlas, provide the means for targeted proteomics, system-wide observations, and cross-species observational studies, but pigs have so far been underrepresented in existing repositories. We here present a significantly improved build of the Pig PeptideAtlas, which includes pig proteome data from 25 tissues and three body fluid types mapped to 7139 canonical proteins. The content of the Pig PeptideAtlas reflects actively ongoing research within the veterinary proteomics domain, and this article demonstrates how the expression of isoform-unique peptides can be observed across distinct tissues and body fluids. The Pig PeptideAtlas is a unique resource for use in animal proteome research, particularly biomarker discovery and for preliminary design of SRM assays, which are equally important for progress in research that supports farm animal production and veterinary health, as for developing pig models with relevance to human health research. PMID:26699206

  2. Equitably sharing benefits from the utilization of natural genetic resources: the Brazilian interpretation of the Convention of Biological Diversity

    NARCIS (Netherlands)

    Pena-Neira, S.; Dieperink, C.; Addink, G.H.

    2002-01-01

    The utilization of natural genetic resources could yield great benefits. The Convention on Biological Diversity introduced a number of rules concerning the sharing of these benefits. However, the interpretation and application (legal implementation) of these rules is a matter of discussion among spe

  3. Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)

    DEFF Research Database (Denmark)

    Hrdlicka, Patrick J; Andersen, Nicolai K; Jepsen, Jan S;

    2005-01-01

    The synthesis of branched and conformationally restricted analogs of the anticancer nucleosides 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd) is presented. Molecular modeling and (1)H NMR coupling constant analysis revealed that the furanose rings of all analogs except the LNA analog...... are conformationally biased towards South conformation, and are thus mimicking the structure of ECyd. All target nucleosides were devoid of anti-HIV or anticancer activity....

  4. The SOL Genomics Network. A Comparative Resource for Solanaceae Biology and Beyond1

    Science.gov (United States)

    Mueller, Lukas A.; Solow, Teri H.; Taylor, Nicolas; Skwarecki, Beth; Buels, Robert; Binns, John; Lin, Chenwei; Wright, Mark H.; Ahrens, Robert; Wang, Ying; Herbst, Evan V.; Keyder, Emil R.; Menda, Naama; Zamir, Dani; Tanksley, Steven D.

    2005-01-01

    The SOL Genomics Network (SGN; http://sgn.cornell.edu) is a rapidly evolving comparative resource for the plants of the Solanaceae family, which includes important crop and model plants such as potato (Solanum tuberosum), eggplant (Solanum melongena), pepper (Capsicum annuum), and tomato (Solanum lycopersicum). The aim of SGN is to relate these species to one another using a comparative genomics approach and to tie them to the other dicots through the fully sequenced genome of Arabidopsis (Arabidopsis thaliana). SGN currently houses map and marker data for Solanaceae species, a large expressed sequence tag collection with computationally derived unigene sets, an extensive database of phenotypic information for a mutagenized tomato population, and associated tools such as real-time quantitative trait loci. Recently, the International Solanaceae Project (SOL) was formed as an umbrella organization for Solanaceae research in over 30 countries to address important questions in plant biology. The first cornerstone of the SOL project is the sequencing of the entire euchromatic portion of the tomato genome. SGN is collaborating with other bioinformatics centers in building the bioinformatics infrastructure for the tomato sequencing project and implementing the bioinformatics strategy of the larger SOL project. The overarching goal of SGN is to make information available in an intuitive comparative format, thereby facilitating a systems approach to investigations into the basis of adaptation and phenotypic diversity in the Solanaceae family, other species in the Asterid clade such as coffee (Coffea arabica), Rubiaciae, and beyond. PMID:16010005

  5. Women are underrepresented on the editorial boards of journals in environmental biology and natural resource management

    Directory of Open Access Journals (Sweden)

    Alyssa H. Cho

    2014-08-01

    Full Text Available Despite women earning similar numbers of graduate degrees as men in STEM disciplines, they are underrepresented in upper level positions in both academia and industry. Editorial board memberships are an important example of such positions; membership is both a professional honor in recognition of achievement and an opportunity for professional advancement. We surveyed 10 highly regarded journals in environmental biology, natural resource management, and plant sciences to quantify the number of women on their editorial boards and in positions of editorial leadership (i.e., Associate Editors and Editors-in-Chief from 1985 to 2013. We found that during this time period only 16% of subject editors were women, with more pronounced disparities in positions of editorial leadership. Although the trend was towards improvement over time, there was surprising variation between journals, including those with similar disciplinary foci. While demographic changes in academia may reduce these disparities over time, we argue journals should proactively strive for gender parity on their editorial boards. This will both increase the number of women afforded the opportunities and benefits that accompany board membership and increase the number of role models and potential mentors for early-career scientists and students.

  6. MetNet Online: a novel integrated resource for plant systems biology

    Directory of Open Access Journals (Sweden)

    Sucaet Yves

    2012-10-01

    Full Text Available Abstract Background Plants are important as foods, pharmaceuticals, biorenewable chemicals, fuel resources, bioremediation tools and general tools for recombinant technology. The study of plant biological pathways is advanced by easy access to integrated data sources. Today, various plant data sources are scattered throughout the web, making it increasingly complicated to build comprehensive datasets. Results MetNet Online is a web-based portal that provides access to a regulatory and metabolic plant pathway database. The database and portal integrate Arabidopsis, soybean (Glycine max and grapevine (Vitis vinifera data. Pathways are enriched with known or predicted information on sub cellular location. MetNet Online enables pathways, interactions and entities to be browsed or searched by multiple categories such as sub cellular compartment, pathway ontology, and GO term. In addition to this, the “My MetNet” feature allows registered users to bookmark content and track, import and export customized lists of entities. Users can also construct custom networks using existing pathways and/or interactions as building blocks. Conclusion The site can be reached at http://www.metnetonline.org. Extensive video tutorials on how to use the site are available through http://www.metnetonline.org/tutorial/.

  7. Women are underrepresented on the editorial boards of journals in environmental biology and natural resource management.

    Science.gov (United States)

    Cho, Alyssa H; Johnson, Shelly A; Schuman, Carrie E; Adler, Jennifer M; Gonzalez, Oscar; Graves, Sarah J; Huebner, Jana R; Marchant, D Blaine; Rifai, Sami W; Skinner, Irina; Bruna, Emilio M

    2014-01-01

    Despite women earning similar numbers of graduate degrees as men in STEM disciplines, they are underrepresented in upper level positions in both academia and industry. Editorial board memberships are an important example of such positions; membership is both a professional honor in recognition of achievement and an opportunity for professional advancement. We surveyed 10 highly regarded journals in environmental biology, natural resource management, and plant sciences to quantify the number of women on their editorial boards and in positions of editorial leadership (i.e., Associate Editors and Editors-in-Chief) from 1985 to 2013. We found that during this time period only 16% of subject editors were women, with more pronounced disparities in positions of editorial leadership. Although the trend was towards improvement over time, there was surprising variation between journals, including those with similar disciplinary foci. While demographic changes in academia may reduce these disparities over time, we argue journals should proactively strive for gender parity on their editorial boards. This will both increase the number of women afforded the opportunities and benefits that accompany board membership and increase the number of role models and potential mentors for early-career scientists and students.

  8. Optimization of the cryopreservation of biological resources, Toxoplasma gondii tachyzoites, using flow cytometry.

    Science.gov (United States)

    Mzabi, Alexandre; Escotte-Binet, Sandie; Le Naour, Richard; Ortis, Naïma; Audonnet, Sandra; Dardé, Marie-Laure; Aubert, Dominique; Villena, Isabelle

    2015-12-01

    The conservation of Toxoplasma gondii strains isolated from humans and animals is essential for conducting studies on Toxoplasma. Conservation is the main function of the French Biological Toxoplasma Resource Centre (BRC Toxoplasma, France, http://www.toxocrb.com/). In this study, we have determined the suitability of a standard cryopreservation methodology for different Toxoplasma strains using the viability of tachyzoites assayed by flow cytometry with dual fluorescent labelling (calcein acetoxymethyl ester and propidium iodide) of tachyzoites. This method provides a comparative quantitative assessment of viability after thawing. The results helped to define and refine quality criteria before tachyzoite cryopreservation and optimization of the cryopreservation parameters. The optimized cryopreservation method uses a volume of 1.0 mL containing 8 × 10(6) tachyzoites, in Iscove's Modified Dulbecco's Medium (IMDM) containing 10% foetal calf serum (FCS). The cryoprotectant additive is 10% v/v Me2SO without incubation. A cooling rate of ∼1 °C/min to -80 °C followed, after 48 h, by storage in liquid nitrogen. Thawing was performed using a 37 °C water bath that produced a warming rate of ∼100 °C/min, and samples were then diluted 1:5 in IMDM with 5% FCS, and centrifuged and resuspended for viability assessment.

  9. The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities.

    Science.gov (United States)

    Stewart, Elizabeth; Federico, Sara; Karlstrom, Asa; Shelat, Anang; Sablauer, Andras; Pappo, Alberto; Dyer, Michael A

    2016-03-15

    Significant advances have been made over the past 25 years in our understanding of the most common adult solid tumors such as breast, colon, lung and prostate cancer. Much less is known about childhood solid tumors because they are rare and because they originate in developing organs during fetal development, childhood and adolescence. It can be very difficult to study the cellular origins of pediatric solid tumors in developing organs characterized by rapid proliferative expansion, growth factor signaling, developmental angiogenesis, programmed cell death, tissue reorganization and cell migration. Not only has the etiology of pediatric cancer remained elusive because of their developmental origins, but it also makes it more difficult to treat. Molecular targeted therapeutics that alter developmental pathway signaling may have devastating effects on normal organ development. Therefore, basic research focused on the mechanisms of development provides an essential foundation for pediatric solid tumor translational research. In this article, we describe new resources available for the developmental biology and oncology research communities. In a companion paper, we present the detailed characterization of an orthotopic xenograft of a pediatric solid tumor derived from sympathoadrenal lineage during development. PMID:26068307

  10. Women are underrepresented on the editorial boards of journals in environmental biology and natural resource management.

    Science.gov (United States)

    Cho, Alyssa H; Johnson, Shelly A; Schuman, Carrie E; Adler, Jennifer M; Gonzalez, Oscar; Graves, Sarah J; Huebner, Jana R; Marchant, D Blaine; Rifai, Sami W; Skinner, Irina; Bruna, Emilio M

    2014-01-01

    Despite women earning similar numbers of graduate degrees as men in STEM disciplines, they are underrepresented in upper level positions in both academia and industry. Editorial board memberships are an important example of such positions; membership is both a professional honor in recognition of achievement and an opportunity for professional advancement. We surveyed 10 highly regarded journals in environmental biology, natural resource management, and plant sciences to quantify the number of women on their editorial boards and in positions of editorial leadership (i.e., Associate Editors and Editors-in-Chief) from 1985 to 2013. We found that during this time period only 16% of subject editors were women, with more pronounced disparities in positions of editorial leadership. Although the trend was towards improvement over time, there was surprising variation between journals, including those with similar disciplinary foci. While demographic changes in academia may reduce these disparities over time, we argue journals should proactively strive for gender parity on their editorial boards. This will both increase the number of women afforded the opportunities and benefits that accompany board membership and increase the number of role models and potential mentors for early-career scientists and students. PMID:25177537

  11. The Use of Quality Benchmarking in Assessing Web Resources for the Dermatology Virtual Branch Library of the National electronic Library for Health (NeLH)

    OpenAIRE

    Boulos, MN Kamel; Roudsari, AV; Gordon, C.; Gray, JA Muir

    2001-01-01

    Background In 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health to provide clinicians, healthcare managers and planners, patients and the public with easy, round the clock access to high quality, up-to-date electronic information on health and healthcare. The Virtual Branch Libraries are among the most important components of the National electronic Library for Health . They aim at creating online kno...

  12. A history of the Water Resources Branch of the United States Geological Survey: vol. III years of 50-50 cooperation, July 1, 1928 to June 30, 1939

    Science.gov (United States)

    Follansbee, Robert

    1944-01-01

    The 11-year period from July 1, 1928, to June 30, 1939, was one of violent contrasts , both naturall and man-made; great floods and severe droughts occurred and great industrial activity 'W'as· succeeded by deep and persistent depression which droughts made even more devastating. It spans the· time from the first year of 50-50 cooperation with the States, to the last year that Nathan C. Grover was Chief of the Branch.

  13. Risk Factor Assessment Branch (RFAB)

    Science.gov (United States)

    The Risk Factor Assessment Branch (RFAB) focuses on the development, evaluation, and dissemination of high-quality risk factor metrics, methods, tools, technologies, and resources for use across the cancer research continuum, and the assessment of cancer-related risk factors in the population.

  14. Social and Economic Analysis Branch: integrating policy, social, economic, and natural science

    Science.gov (United States)

    Schuster, Rudy; Walters, Katie D.

    2015-01-01

    The Fort Collins Science Center's Social and Economic Analysis Branch provides unique capabilities in the U.S. Geological Survey by leading projects that integrate social, behavioral, economic, and natural science in the context of human–natural resource interactions. Our research provides scientific understanding and support for the management and conservation of our natural resources in support of multiple agency missions. We focus on meeting the scientific needs of the Department of the Interior natural resource management bureaus in addition to fostering partnerships with other Federal and State managers to protect, restore, and enhance our environment. The Social and Economic Analysis Branch has an interdisciplinary group of scientists whose primary functions are to conduct both theoretical and applied social science research, provide technical assistance, and offer training to support the development of skills in natural resource management activities. Management and research issues associated with human-resource interactions typically occur in a unique context and require knowledge of both natural and social sciences, along with the skill to integrate multiple science disciplines. In response to these challenging contexts, Social and Economic Analysis Branch researchers apply a wide variety of social science concepts and methods which complement our rangeland/agricultural, wildlife, ecology, and biology capabilities. The goal of the Social and Economic Analysis Branch's research is to enhance natural-resource management, agency functions, policies, and decisionmaking.

  15. Animal-based medicines: biological prospection and the sustainable use of zootherapeutic resources

    Directory of Open Access Journals (Sweden)

    Eraldo M. Costa-Neto

    2005-03-01

    Full Text Available Animals have been used as medicinal resources for the treatment and relieve of a myriad of illnesses and diseases in practically every human culture. Although considered by many as superstition, the pertinence of traditional medicine based on animals cannot be denied since they have been methodically tested by pharmaceutical companies as sources of drugs to the modern medical science. The phenomenon of zootherapy represents a strong evidence of the medicinal use of animal resources. Indeed, drug companies and agribusiness firms have been evaluating animals for decades without paying anything to the countries from where these genetic resources are found. The use of animals' body parts as folk medicines is relevant because it implies additional pressure over critical wild populations. It is argued that many animal species have been overexploited as sources of medicines for the traditional trade. Additionally, animal populations have become depleted or endangered as a result of their use as experimental subjects or animal models. Research on zootherapy should be compatible with the welfare of the medicinal animals, and the use of their by-products should be done in a sustainable way. It is discussed that sustainability is now required as the guiding principle for biological conservation.Os animais são utilizados como recursos medicinais para o tratamento e alívio de um gama de doenças e enfermidades em praticamente toda cultura humana. A pertinência da medicina tradicional baseada em animais, embora considerada como superstição, não deve ser negada uma vez que os animais têm sido testados metodicamente pelas companhias farmacêuticas como fontes de drogas para a ciência médica moderna. O fenômeno da zooterapia representa uma forte evidência do uso medicinal de recursos animais. De fato, as indústrias farmacêuticas e de agronegócios há décadas vêm avaliando animais sem pagar tributos aos países detentores desses recursos gen

  16. Patterns of database citation in articles and patents indicate long-term scientific and industry value of biological data resources.

    Science.gov (United States)

    Bousfield, David; McEntyre, Johanna; Velankar, Sameer; Papadatos, George; Bateman, Alex; Cochrane, Guy; Kim, Jee-Hyub; Graef, Florian; Vartak, Vid; Alako, Blaise; Blomberg, Niklas

    2016-01-01

    Data from open access biomolecular data resources, such as the European Nucleotide Archive and the Protein Data Bank are extensively reused within life science research for comparative studies, method development and to derive new scientific insights. Indicators that estimate the extent and utility of such secondary use of research data need to reflect this complex and highly variable data usage. By linking open access scientific literature, via Europe PubMedCentral, to the metadata in biological data resources we separate data citations associated with a deposition statement from citations that capture the subsequent, long-term, reuse of data in academia and industry.  We extend this analysis to begin to investigate citations of biomolecular resources in patent documents. We find citations in more than 8,000 patents from 2014, demonstrating substantial use and an important role for data resources in defining biological concepts in granted patents to both academic and industrial innovators. Combined together our results indicate that the citation patterns in biomedical literature and patents vary, not only due to citation practice but also according to the data resource cited. The results guard against the use of simple metrics such as citation counts and show that indicators of data use must not only take into account citations within the biomedical literature but also include reuse of data in industry and other parts of society by including patents and other scientific and technical documents such as guidelines, reports and grant applications. PMID:27092246

  17. On the Cooperative Preservation of Printed Documentary Resources in the Central-Branch Libraries System%总分馆体制下印刷型文献资源协同保存探讨

    Institute of Scientific and Technical Information of China (English)

    罗婉娜

    2013-01-01

    通过对图书馆印刷型文献馆藏现状、总分馆体制发展趋势的分析,结合国内外图书馆多年实践经验,以东莞为例,探讨图书馆在总分馆体制管理架构下,以协同保存的方式解决区域内图书馆不断增长的印刷型文献的保存、利用问题。%Through analysis of the current collection of printed documentary resources and the development situations of central-branch libraries system , and of the experience of domestic and foreign libraries for years , this paper, taking Dongguan as an example, probes into how to solve the problems of the preservation and utilization of the increasingly large number of printed docu -mentary resources in the regional library under the central-branch libraries system with a cooperative preservation mode .

  18. Geospatial characteristics of Florida's coastal and offshore environments: Distribution of important habitats for coastal and offshore biological resources and offshore sand resources

    Science.gov (United States)

    Demopoulos, Amanda W.J.; Foster, Ann M.; Jones, Michal L.; Gualtieri, Daniel J.

    2011-01-01

    The Geospatial Characteristics GeoPDF of Florida's Coastal and Offshore Environments is a comprehensive collection of geospatial data describing the political boundaries and natural resources of Florida. This interactive map provides spatial information on bathymetry, sand resources, and locations of important habitats (for example, Essential Fish Habitats (EFH), nesting areas, strandings) for marine invertebrates, fish, reptiles, birds, and marine mammals. The map should be useful to coastal resource managers and others interested in marine habitats and submerged obstructions of Florida's coastal region. In particular, as oil and gas explorations continue to expand, the map can be used to explore information regarding sensitive areas and resources in the State of Florida. Users of this geospatial database will have access to synthesized information in a variety of scientific disciplines concerning Florida's coastal zone. This powerful tool provides a one-stop assembly of data that can be tailored to fit the needs of many natural resource managers. The map was originally developed to assist the Bureau of Ocean Energy Management, Regulation, and Enforcement (BOEMRE) and coastal resources managers with planning beach restoration projects. The BOEMRE uses a systematic approach in planning the development of submerged lands of the Continental Shelf seaward of Florida's territorial waters. Such development could affect the environment. BOEMRE is required to ascertain the existing physical, biological, and socioeconomic conditions of the submerged lands and estimate the impact of developing these lands. Data sources included the National Oceanic and Atmospheric Administration, BOEMRE, Florida Department of Environmental Protection, Florida Geographic Data Library, Florida Fish and Wildlife Conservation Commission, Florida Natural Areas Inventory, and the State of Florida, Bureau of Archeological Research. Federal Geographic Data Committee (FGDC) compliant metadata are

  19. China Strengthens Macro-management in Petrochemical Branches

    Institute of Scientific and Technical Information of China (English)

    Xu Hui

    1997-01-01

    @@ China will strengthen macro-management in petrochemical branches in order to reasonably utilize the national petroleum resources and improve its competitive capacity in international refinery industrial market.

  20. Some aspects of biological production and fishery resources of the EEZ of India

    Digital Repository Service at National Institute of Oceanography (India)

    Bhargava, R.M.S.

    Region and season-wise biological production in the Exclusive Economic Zone (EEZ) of India has been computed from the data of more than twenty years available at the Indian National Oceanographic Data Centre of the National Institute of Oceanography...

  1. Information resources and the correlation of response patterns between biological end points

    Energy Technology Data Exchange (ETDEWEB)

    Malling, H.V. [National Institute of Environmental Health Sciences, Research Triangle Park, NC (United States); Wassom, J.S. [Oak Ridge National Laboratory, TN (United States)

    1990-12-31

    This paper focuses on the analysis of information for mutagenesis, a biological end point that is important in the overall process of assessing possible adverse health effects from chemical exposure. 17 refs.

  2. The Potential Use of Indigobush (Amorpha fruticosa L.) as Natural Resource of Biologically Active Compounds

    OpenAIRE

    Tamara Jakovljević; Jasna Halambek; Kristina Radošević; Karla Hanousek; Marija Gradečki-Poštenjak; Višnja Gaurina Srček; Ivana Radojčić Redovniković; Alessandra De Marco

    2015-01-01

    Background and Purpose: Recent research indicates that a weed like Indigobush (Amorpha fruticosa L.) gives great opportunities for its commercialization through a rich spectrum of its beneficial biological features with possible use in the forestry and biotechnology field. Therefore, in this study we wanted to explore some of potential application of Indigobush extract, as a source of biologically active compounds, for animal cell culturing as well as green corrosion inhibitors. Materials ...

  3. Making United States Integrated Ocean Observing System (U.S. IOOS) inclusive of marine biological resources

    Science.gov (United States)

    Moustahfid, H.; Potemra, J.; Goldstein, P.; Mendelssohn, R.; Desrochers, A.

    2011-01-01

    An important Data Management and Communication (DMAC) goal is to enable a multi-disciplinary view of the ocean environment by facilitating discovery and integration of data from various sources, projects and scientific domains. United States Integrated Ocean Observing System (U.S. IOOS) DMAC functional requirements are based upon guidelines for standardized data access services, data formats, metadata, controlled vocabularies, and other conventions. So far, the data integration effort has focused on geophysical U.S. IOOS core variables such as temperature, salinity, ocean currents, etc. The IOOS Biological Observations Project is addressing the DMAC requirements that pertain to biological observations standards and interoperability applicable to U.S. IOOS and to various observing systems. Biological observations are highly heterogeneous and the variety of formats, logical structures, and sampling methods create significant challenges. Here we describe an informatics framework for biological observing data (e.g. species presence/absence and abundance data) that will expand information content and reconcile standards for the representation and integration of these biological observations for users to maximize the value of these observing data. We further propose that the approach described can be applied to other datasets generated in scientific observing surveys and will provide a vehicle for wider dissemination of biological observing data. We propose to employ data definition conventions that are well understood in U.S. IOOS and to combine these with ratified terminologies, policies and guidelines. ?? 2011 MTS.

  4. BioGRID: A Resource for Studying Biological Interactions in Yeast.

    Science.gov (United States)

    Oughtred, Rose; Chatr-aryamontri, Andrew; Breitkreutz, Bobby-Joe; Chang, Christie S; Rust, Jennifer M; Theesfeld, Chandra L; Heinicke, Sven; Breitkreutz, Ashton; Chen, Daici; Hirschman, Jodi; Kolas, Nadine; Livstone, Michael S; Nixon, Julie; O'Donnell, Lara; Ramage, Lindsay; Winter, Andrew; Reguly, Teresa; Sellam, Adnane; Stark, Chris; Boucher, Lorrie; Dolinski, Kara; Tyers, Mike

    2016-01-01

    The Biological General Repository for Interaction Datasets (BioGRID) is a freely available public database that provides the biological and biomedical research communities with curated protein and genetic interaction data. Structured experimental evidence codes, an intuitive search interface, and visualization tools enable the discovery of individual gene, protein, or biological network function. BioGRID houses interaction data for the major model organism species--including yeast, nematode, fly, zebrafish, mouse, and human--with particular emphasis on the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe as pioneer eukaryotic models for network biology. BioGRID has achieved comprehensive curation coverage of the entire literature for these two major yeast models, which is actively maintained through monthly curation updates. As of September 2015, BioGRID houses approximately 335,400 biological interactions for budding yeast and approximately 67,800 interactions for fission yeast. BioGRID also supports an integrated posttranslational modification (PTM) viewer that incorporates more than 20,100 yeast phosphorylation sites curated through its sister database, the PhosphoGRID. PMID:26729913

  5. Biologic

    CERN Document Server

    Kauffman, L H

    2002-01-01

    In this paper we explore the boundary between biology and the study of formal systems (logic). In the end, we arrive at a summary formalism, a chapter in "boundary mathematics" where there are not only containers but also extainers ><, entities open to interaction and distinguishing the space that they are not. The boundary algebra of containers and extainers is to biologic what boolean algebra is to classical logic. We show how this formalism encompasses significant parts of the logic of DNA replication, the Dirac formalism for quantum mechanics, formalisms for protein folding and the basic structure of the Temperley Lieb algebra at the foundations of topological invariants of knots and links.

  6. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    2002-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...... set. Particular studies are made of branched polynomial covering maps arising from Riemann surfaces and from knots in the 3-sphere. (C) 2001 Elsevier Science B.V. All rights reserved....

  7. Investigation of oil drilling impacts to aquatic habitat resources: In Situ biological assessment of the photoinduced toxicity of environmental releases of crude oil

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This study proposed a biological assessment of a recent crude oil spill for potential impacts to aquatic resources due to petroleum hydrocarbon wastes. The...

  8. The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology.

    Science.gov (United States)

    Eppig, Janan T; Bult, Carol J; Kadin, James A; Richardson, Joel E; Blake, Judith A; Anagnostopoulos, A; Baldarelli, R M; Baya, M; Beal, J S; Bello, S M; Boddy, W J; Bradt, D W; Burkart, D L; Butler, N E; Campbell, J; Cassell, M A; Corbani, L E; Cousins, S L; Dahmen, D J; Dene, H; Diehl, A D; Drabkin, H J; Frazer, K S; Frost, P; Glass, L H; Goldsmith, C W; Grant, P L; Lennon-Pierce, M; Lewis, J; Lu, I; Maltais, L J; McAndrews-Hill, M; McClellan, L; Miers, D B; Miller, L A; Ni, L; Ormsby, J E; Qi, D; Reddy, T B K; Reed, D J; Richards-Smith, B; Shaw, D R; Sinclair, R; Smith, C L; Szauter, P; Walker, M B; Walton, D O; Washburn, L L; Witham, I T; Zhu, Y

    2005-01-01

    The Mouse Genome Database (MGD) forms the core of the Mouse Genome Informatics (MGI) system (http://www.informatics.jax.org), a model organism database resource for the laboratory mouse. MGD provides essential integration of experimental knowledge for the mouse system with information annotated from both literature and online sources. MGD curates and presents consensus and experimental data representations of genotype (sequence) through phenotype information, including highly detailed reports about genes and gene products. Primary foci of integration are through representations of relationships among genes, sequences and phenotypes. MGD collaborates with other bioinformatics groups to curate a definitive set of information about the laboratory mouse and to build and implement the data and semantic standards that are essential for comparative genome analysis. Recent improvements in MGD discussed here include the enhancement of phenotype resources, the re-development of the International Mouse Strain Resource, IMSR, the update of mammalian orthology datasets and the electronic publication of classic books in mouse genetics.

  9. Proceedings of the workshop "Development of biological decision support systems for resource managers": Denver, Colorado, October 27-29, 1998

    Science.gov (United States)

    Getter, James; D'Erchia, Terry D.; Root, Ralph; Getter, James; D'Erchia, Terry D.; Root, Ralph

    1999-01-01

    The format for this 3-day workshop (27-29 October 1998) included plenary presentations by USGS Biological Resources Division (BRD) and U.S. Fish and Wildlife Service per onnel who u e and develop decision support systems (DSS); breakout ses ions addressing DSS technical information aspect , outreach/ customer requirements, and future perspectives; and a DSS Steering Committee meeting to evaluate work hop goals and to provide guidance for fu ture efforts. Steering committee action item developed from workshop inputs were to ( I) develop a "DSS framework" document for u e in biological research. (2) develop a "proof of concept" DSS based upon the framework document, and (3) integrate decision support ystem into BRD program elements.

  10. Xylella fastidiosa comparative genomic database is an information resource to explore the annotation, genomic features, and biology of different strains

    Directory of Open Access Journals (Sweden)

    Alessandro M. Varani

    2012-01-01

    Full Text Available The Xylella fastidiosa comparative genomic database is a scientific resource with the aim to provide a user-friendly interface for accessing high-quality manually curated genomic annotation and comparative sequence analysis, as well as for identifying and mapping prophage-like elements, a marked feature of Xylella genomes. Here we describe a database and tools for exploring the biology of this important plant pathogen. The hallmarks of this database are the high quality genomic annotation, the functional and comparative genomic analysis and the identification and mapping of prophage-like elements. It is available from web site http://www.xylella.lncc.br.

  11. Geographic information system in marine biology: Way for sustainable utilization of living resources

    Digital Repository Service at National Institute of Oceanography (India)

    Chavan, V.S.; Sreepada, R.A.

    applications of GIS in the field of marine biology and elaborates on the marits and demerits of such an application. It also lists a few of the locally available GIS and their cost-effectiveness. It further elaborates on the data validation that one required...

  12. DC-ATLAS : a systems biology resource to dissect receptor specific signal transduction in dendritic cells

    NARCIS (Netherlands)

    Cavalieri, D.; Rivero, D.; Beltrame, L.; Buschow, S.I.; Calura, E.; Rizzetto, L.; Gessani, S.; Gauzzi, M.C.; Reith, W.; Baur, A.; Bonaiuti, R.; Brandizi, M.; Filippo, C. De; D'Oro, U.; Draghici, S.; Dunand-Sauthier, I.; Gatti, E.; Granucci, F.; Gundel, M.; Kramer, M.; Kuka, M.; Lanyi, A.; Melief, C.J.; Montfoort, N. van; Ostuni, R.; Pierre, P.; Popovici, R.; Rajnavolgyi, E.; Schierer, S.; Schuler, G.; Soumelis, V.; Splendiani, A.; Stefanini, I.; Torcia, M.G.; Zanoni, I.; Zollinger, R.; Figdor, C.G.; Austyn, J.M.

    2010-01-01

    BACKGROUND: The advent of Systems Biology has been accompanied by the blooming of pathway databases. Currently pathways are defined generically with respect to the organ or cell type where a reaction takes place. The cell type specificity of the reactions is the foundation of immunological research,

  13. Genetic Resources of Energy Crops: Biological Systems to Combat Climate Change

    Science.gov (United States)

    Biological systems are expected to contribute to renewable energy production, help stabilize rising levels of green house gases (GHG), and mitigate the risk of global climate change (GCC). Bioenergy crop plants that function as solar energy collectors and thermo-chemical energy storage systems are t...

  14. Professional orientation strategy in agricultural engineering; a contribution to the management of human resources for the scientist-professional work in the agricultural branch

    International Nuclear Information System (INIS)

    Full text: The management of human resources (GRH) has become a strategic element important for the progress of organizations, taking into account that represents the human potential based on its projection and development and in the achievement of the objectives and goals that will mark them, recognizing in the 21st century as 'the resort competitive more important, constituting your training an investment, not a cost' (Hammer and Champy, 1994). The actions contained in this strategy are an example of the necessary and fruitful relationship between the substantive functions of the University: University - extension as premise for a real correspondence between the University and the environment in accordance with the needs which demand scientific development of society. (author)

  15. Biological productivity and potential resources of the exclusive economic zone (EEZ) of India

    Digital Repository Service at National Institute of Oceanography (India)

    Goswami, S.C.

    degree square was calculated from the production data. The potential fishery resources including demersal fishery of the entire EEZ of India worked out to be 3.45 million tones yr sup(-1). Since the annual fishery production is around 2.7 million tones...

  16. Resources.

    Science.gov (United States)

    Stewart, John; MacDonald, Ian

    1980-01-01

    Presents a guide to resources on television drama available to teachers for classroom use in television curriculum. Lists American and British television drama videorecordings of both series and individual presentations and offers a bibliography of "one-off" single fiction plays produced for British television. (JMF)

  17. GoMiner: a resource for biological interpretation of genomic and proteomic data

    OpenAIRE

    Barry R Zeeberg; Feng, Weimin; Wang, Geoffrey; Wang, May D.; Fojo, Anthony T; Sunshine, Margot; Narasimhan, Sudarshan; Kane, David W; Reinhold, William C.; Lababidi, Samir; Bussey, Kimberly J.; Riss, Joseph; Barrett, J Carl; John N Weinstein

    2003-01-01

    We have developed GoMiner, a program package that organizes lists of 'interesting' genes (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology. GoMiner provides quantitative and statistical output files and two useful visualizations. The first is a tree-like structure analogous to that in the AmiGO browser and the second is a compact, dynamically interactive 'directed acyclic graph'. Genes displayed in GoMi...

  18. Research progress in the phytochemistry and biology of Ilex pharmaceutical resources

    OpenAIRE

    Dacheng Hao; Xiaojie Gu; Peigen Xiao; Zhanguo Liang; Lijia Xu; Yong Peng

    2013-01-01

    Ilex is a botanical source for various health-promoting and pharmaceutically active compounds that have been used in traditional Chinese medicine and food for thousands of years. Increasing interest in Ilex pharmaceutical and food resources has led to additional discoveries of terpenoids, saponins, polyphenols (especially flavonoids), glycosides, and many other compounds in various Ilex species, and to investigation of their chemotaxonomy, molecular phylogeny and pharmacology. In continuation...

  19. Increasing population and declining biological resources in the context of global change and globalization

    Indian Academy of Sciences (India)

    P S Ramakrishnan

    2001-11-01

    In the context of over-consumption of natural resources in the name of development and rapid industrialization by a small section of the human population that is rapidly growing, the world is currently faced with a variety of environmental uncertainties. `Global change’ covering a whole variety of ecological issues, and `globalization’ in an economic sense, are two major phenomena that are responsible for these uncertainties. There is increasing evidence to suggest that the developing countries more than the developed, particularly the marginalized traditional (those living close to nature and natural resources) societies would be the worst sufferers. In order to cope with this problem in a situation where the traditional societies have to cope with rapidly depleting biodiversity on which they are dependant for their livelihood, there is an urgent need to explore additional pathways for sustainable management of natural resources and societal development. Such pathways should be based on a landscape management strategy, that takes into consideration the rich traditional ecological knowledge (TEK) that these societies have. This is critical because TEK is the connecting link between conservation and sustainable development. This paper explores the possibilities in this direction through a balanced approach to development, that links the `traditional’ with the `modern’, in a location-specific way.

  20. PlanMine--a mineable resource of planarian biology and biodiversity.

    Science.gov (United States)

    Brandl, Holger; Moon, HongKee; Vila-Farré, Miquel; Liu, Shang-Yun; Henry, Ian; Rink, Jochen C

    2016-01-01

    Planarian flatworms are in the midst of a renaissance as a model system for regeneration and stem cells. Besides two well-studied model species, hundreds of species exist worldwide that present a fascinating diversity of regenerative abilities, tissue turnover rates, reproductive strategies and other life history traits. PlanMine (http://planmine.mpi-cbg.de/) aims to accomplish two primary missions: First, to provide an easily accessible platform for sharing, comparing and value-added mining of planarian sequence data. Second, to catalyze the comparative analysis of the phenotypic diversity amongst planarian species. Currently, PlanMine houses transcriptomes independently assembled by our lab and community contributors. Detailed assembly/annotation statistics, a custom-developed BLAST viewer and easy export options enable comparisons at the contig and assembly level. Consistent annotation of all transcriptomes by an automated pipeline, the integration of published gene expression information and inter-relational query tools provide opportunities for mining planarian gene sequences and functions. For inter-species comparisons, we include transcriptomes of, so far, six planarian species, along with images, expert-curated information on their biology and pre-calculated cross-species sequence homologies. PlanMine is based on the popular InterMine system in order to make the rich biology of planarians accessible to the general life sciences research community. PMID:26578570

  1. Yucca Mountain Biological Resources Monitoring Program; Progress report, October 1992--December 1993

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-05-01

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of (as amended in 1987) to study and characterize the suitability of Yucca Mountain as a potential geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities do not adversely affect the environment at Yucca Mountain, a program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG&G Energy Measurements, Inc. (EG&G/EM) from October 1992 through December 1993 for six program areas within the Terrestrial Ecosystem component of the environmental program for the Yucca Mountain Site Characterization Project (YMP): Site Characterization Effects, Desert Tortoises (Gopherus agassizii), Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support.

  2. Final Report - Phylogenomic tools and web resources for the Systems Biology Knowledgebase

    Energy Technology Data Exchange (ETDEWEB)

    Sjolander, Kimmen [Univ. of California, Berkeley, CA (United States)

    2014-12-08

    The major advance during this last reporting period (8/15/12 to present) is our release of data on the PhyloFacts website: phylogenetic trees, multiple sequence alignments and other data for protein families are now available for download from http://phylogenomics.berkeley.edu/data/. This project as a whole aimed to develop high-throughput functional annotation systems that exploit information from protein 3D structure and evolution to provide highly precise inferences of various aspects of gene function, including molecular function, biological process, pathway association, Pfam domains, cellular localization and so on. We accomplished these aims by developing and testing different systems on a database of protein family trees: the PhyloFacts Phylogenomic Encyclopedia (at http://phylogenomics.berkeley.edu/phylofacts/ ).

  3. Yucca Mountain Biological Resources Monitoring Program. Progress report, October 1992--December 1993

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of (as amended in 1987) to study and characterize the suitability of Yucca Mountain as a potential geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities do not adversely affect the environment at Yucca Mountain, a program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG ampersand G Energy Measurements, Inc. (EG ampersand G/EM) from October 1992 through December 1993 for six program areas within the Terrestrial Ecosystem component of the environmental program for the Yucca Mountain Site Characterization Project (YMP): Site Characterization Effects, Desert Tortoises (Gopherus agassizii), Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

  4. Final Report - Phylogenomic tools and web resources for the Systems Biology Knowledgebase

    Energy Technology Data Exchange (ETDEWEB)

    Sjolander, Kimmen

    2014-11-07

    The major advance during this last reporting period (8/15/12 to present) is our release of data on the PhyloFacts website: phylogenetic trees, multiple sequence alignments and other data for protein families are now available for download from http://phylogenomics.berkeley.edu/data/. This project as a whole aimed to develop high-throughput functional annotation systems that exploit information from protein 3D structure and evolution to provide highly precise inferences of various aspects of gene function, including molecular function, biological process, pathway association, Pfam domains, cellular localization and so on. We accomplished these aims by developing and testing different systems on a database of protein family trees: the PhyloFacts Phylogenomic Encyclopedia (at http://phylogenomics.berkeley.edu/phylofacts/ ).

  5. High-resolution satellite imagery is an important yet underutilized resource in conservation biology.

    Science.gov (United States)

    Boyle, Sarah A; Kennedy, Christina M; Torres, Julio; Colman, Karen; Pérez-Estigarribia, Pastor E; de la Sancha, Noé U

    2014-01-01

    Technological advances and increasing availability of high-resolution satellite imagery offer the potential for more accurate land cover classifications and pattern analyses, which could greatly improve the detection and quantification of land cover change for conservation. Such remotely-sensed products, however, are often expensive and difficult to acquire, which prohibits or reduces their use. We tested whether imagery of high spatial resolution (≤5 m) differs from lower-resolution imagery (≥30 m) in performance and extent of use for conservation applications. To assess performance, we classified land cover in a heterogeneous region of Interior Atlantic Forest in Paraguay, which has undergone recent and dramatic human-induced habitat loss and fragmentation. We used 4 m multispectral IKONOS and 30 m multispectral Landsat imagery and determined the extent to which resolution influenced the delineation of land cover classes and patch-level metrics. Higher-resolution imagery more accurately delineated cover classes, identified smaller patches, retained patch shape, and detected narrower, linear patches. To assess extent of use, we surveyed three conservation journals (Biological Conservation, Biotropica, Conservation Biology) and found limited application of high-resolution imagery in research, with only 26.8% of land cover studies analyzing satellite imagery, and of these studies only 10.4% used imagery ≤5 m resolution. Our results suggest that high-resolution imagery is warranted yet under-utilized in conservation research, but is needed to adequately monitor and evaluate forest loss and conversion, and to delineate potentially important stepping-stone fragments that may serve as corridors in a human-modified landscape. Greater access to low-cost, multiband, high-resolution satellite imagery would therefore greatly facilitate conservation management and decision-making.

  6. Resource use and cost of care with biologicals in Crohn's disease in South Africa: a retrospective analysis from a payer perspective.

    Science.gov (United States)

    Miot, Jacqui; Smith, Susan; Bhimsan, Niri

    2016-08-01

    Background Crohn's disease is a relapsing remitting inflammatory disease of the gastrointestinal tract. Treatment may require expensive biological therapy in severe patients. Affordability of the high cost anti-TNF-α agents has raised concern although evidence suggests cost-offsets can be achieved. There is little information on the resource utilisation of Crohn's patients in low and middle income countries. Objective The objective of this study is to investigate the resource utilisation and costs associated with biologicals treatment of Crohn's disease. Setting The setting for this study is in private healthcare in South Africa from a payer perspective. Method A retrospective longitudinal analysis of an administrative claims database from a large private healthcare insurer of patients who had at least 1 year claims exposure prior to starting biologicals and 2 years follow-up thereafter. Resource utilisation and costs including total Crohn's costs, hospital admissions and surgery, out of hospital costs, biologicals and chronic medicines were analysed. Main outcome measure The primary objective was to compare the change in resource utilisation and costs for Crohn's related conditions before and after starting biological treatment. Results A cohort of 72 patients was identified with a 35% (p = 0.005) reduction in Crohn's related costs (excluding the cost of biologicals) from ZAR 55,925 (U$5369) 1 year before compared to ZAR 36,293 (U$3484) 2 years after starting biological medicines. However, inclusion of the cost of biologicals more than doubled the total costs to ZAR 150,915 (±91,642) U$14,488 (±8798) in Year 2. Significant reductions in out-of hospital Crohn's related spend was also observed. Conclusions A reduction in healthcare costs is seen following starting biologicals in patients with moderate to severe Crohn's disease. However, the high cost of biological therapy outweighs any possible savings achieved in other areas of healthcare utilisation.

  7. Central Colorado Assessment Project - Application of integrated geologic, geochemical, biologic, and mineral resource studies

    Science.gov (United States)

    Klein, T.L.; Church, S.E.; Caine, J.S.; Schmidt, T.S.; deWitt, E.H.

    2008-01-01

    Central Colorado is one of the fastest-growing regions in the Western United States. Population along the Front Range increased more than 30 percent between 1990 and 2000 (http://www.demographia.com/db-metro3newworld.htm) with some counties within the study area, such as Park County, experiencing greater than 100-percent growth (http://www.censusscope.org/us/s8/rank_popl_growth.html). This growth has caused tremendous demand for natural resources and has created challenging land-management issues related to the interface between wilderness and urban expansion. Management of this wilderness/urban interface will benefit from current digital geoscience information collected by the U.S. Geological Survey (USGS) Central Colorado Assessment Project that began in 2003. Approximately 20,800 square miles (53,800 km2) of land divided almost equally between the public and private sectors were part of the assessment.

  8. The Multinational Arabidopsis Steering Subcommittee for Proteomics Assembles the Largest Proteome Database Resource for Plant Systems Biology

    Energy Technology Data Exchange (ETDEWEB)

    Weckwerth, Wolfram; Baginsky, Sacha; Van Wijk, Klass; Heazlewood, Joshua; Millar, Harvey

    2009-12-01

    In the past 10 years, we have witnessed remarkable advances in the field of plant molecular biology. The rapid development of proteomic technologies and the speed with which these techniques have been applied to the field have altered our perception of how we can analyze proteins in complex systems. At nearly the same time, the availability of the complete genome for the model plant Arabidopsis thaliana was released; this effort provides an unsurpassed resource for the identification of proteins when researchers use MS to analyze plant samples. Recognizing the growth in this area, the Multinational Arabidopsis Steering Committee (MASC) established a subcommittee for A. thaliana proteomics in 2006 with the objective of consolidating databases, technique standards, and experimentally validated candidate genes and functions. Since the establishment of the Multinational Arabidopsis Steering Subcommittee for Proteomics (MASCP), many new approaches and resources have become available. Recently, the subcommittee established a webpage to consolidate this information (www.masc-proteomics.org). It includes links to plant proteomic databases, general information about proteomic techniques, meeting information, a summary of proteomic standards, and other relevant resources. Altogether, this website provides a useful resource for the Arabidopsis proteomics community. In the future, the website will host discussions and investigate the cross-linking of databases. The subcommittee members have extensive experience in arabidopsis proteomics and collectively have produced some of the most extensive proteomics data sets for this model plant (Table S1 in the Supporting Information has a list of resources). The largest collection of proteomics data from a single study in A. thaliana was assembled into an accessible database (AtProteome; http://fgcz-atproteome.unizh.ch/index.php) and was recently published by the Baginsky lab.1 The database provides links to major Arabidopsis online

  9. The Potential Use of Indigobush (Amorpha fruticosa L. as Natural Resource of Biologically Active Compounds

    Directory of Open Access Journals (Sweden)

    Tamara Jakovljević

    2015-05-01

    Full Text Available Background and Purpose: Recent research indicates that a weed like Indigobush (Amorpha fruticosa L. gives great opportunities for its commercialization through a rich spectrum of its beneficial biological features with possible use in the forestry and biotechnology field. Therefore, in this study we wanted to explore some of potential application of Indigobush extract, as a source of biologically active compounds, for animal cell culturing as well as green corrosion inhibitors. Materials and Methods: The effect of ethanol extract of Indigobush seeds was studied on human tumor cell lines (HeLa and MCF-7 and cell viability was determined by WST-1 method after 72 hours of treatment with 6 different extract concentrations (0.5-10 mg∙mL-1. The inhibition effect of Indigobush seeds extract on the corrosion of aluminum in 0.5 M hydrochloric acid solution was investigated by potentiodynamic polarization and electrochemical impedance spectroscopy (EIS methods. Results: Results showed that the addition of Indigobush extract had a stimulatory effect on MCF-7 cells growth at the concentrations >1 mg∙mL-1 while the same effect on HeLa cells was observed only at the highest concentration of Indigobush extract (10 mg∙mL-1. The stimulatory effect of Indigobush extract on cell viability was more pronounced when the cells were grown in a medium with 5% FBS compared to 10% FBS (v/v. Indigobush extract did not show cytotoxic effect on MCF-7 and HeLa cells. Electrochemical studies showed that with increasing extract concentrations (2.5-15 mg∙mL-1 the values of corrosion current densities decrease, while the polarization resistance values increase. The maximum inhibition efficiency of Indigobush extract is reached at concentration of 15 mg∙mL-1 (82.9%. Conclusions: The Indigobush ethanol extract has no cytotoxic effect on human tumor cell lines MCF-7 and HeLa. Results confirmed that extract originated from Indigobush has the potential to utilize for the

  10. Yucca Mountain Biological Resources Monitoring Program. Progress report, January 1994--December 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize the suitability of Yucca Mountain as a potential geological repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities do not adversely affect the environment at Yucca Mountain, a program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG and G Energy Measurements, Inc. (EG and G/EM) from January 1994 through December 1994 for six program areas within the Terrestrial Ecosystem component of the environmental program for the Yucca Mountain Site Characterization Project (YMP): Site Characterization Effects, Desert Tortoises (Gopherus agassizii), Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support.

  11. Yucca Mountain Biological Resources Monitoring Program. Progress report, January 1994--December 1994

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize the suitability of Yucca Mountain as a potential geological repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities do not adversely affect the environment at Yucca Mountain, a program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG and G Energy Measurements, Inc. (EG and G/EM) from January 1994 through December 1994 for six program areas within the Terrestrial Ecosystem component of the environmental program for the Yucca Mountain Site Characterization Project (YMP): Site Characterization Effects, Desert Tortoises (Gopherus agassizii), Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

  12. Melons are branched polymers

    CERN Document Server

    Gurau, Razvan

    2013-01-01

    Melonic graphs constitute the family of graphs arising at leading order in the 1/N expansion of tensor models. They were shown to lead to a continuum phase, reminiscent of branched polymers. We show here that they are in fact precisely branched polymers, that is, they possess Hausdorff dimension 2 and spectral dimension 4/3.

  13. MorusDB: a resource for mulberry genomics and genome biology.

    Science.gov (United States)

    Li, Tian; Qi, Xiwu; Zeng, Qiwei; Xiang, Zhonghuai; He, Ningjia

    2014-01-01

    Mulberry is an important cultivated plant that has received the attention of biologists interested in sericulture and plant-insect interaction. Morus notabilis, a wild mulberry species with a minimal chromosome number is an ideal material for whole-genome sequencing and assembly. The genome and transcriptome of M. notabilis were sequenced and analyzed. In this article, a web-based and open-access database, the Morus Genome Database (MorusDB), was developed to enable easy-to-access and data mining. The MorusDB provides an integrated data source and an easy accession of mulberry large-scale genomic sequencing and assembly, predicted genes and functional annotations, expressed sequence tags (ESTs), transposable elements (TEs), Gene Ontology (GO) terms, horizontal gene transfers between mulberry and silkworm and ortholog and paralog groups. Transcriptome sequencing data for M. notabilis root, leaf, bark, winter bud and male flower can also be searched and downloaded. Furthermore, MorusDB provides an analytical workbench with some built-in tools and pipelines, such as BLAST, Search GO, Mulberry GO and Mulberry GBrowse, to facilitate genomic studies and comparative genomics. The MorusDB provides important genomic resources for scientists working with mulberry and other Moraceae species, which include many important fruit crops. Designed as a basic platform and accompanied by the SilkDB, MorusDB strives to be a comprehensive platform for the silkworm-mulberry interaction studies. Database URL: http://morus.swu.edu.cn/morusdb.

  14. Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps.

    Science.gov (United States)

    Kuperstein, I; Bonnet, E; Nguyen, H-A; Cohen, D; Viara, E; Grieco, L; Fourquet, S; Calzone, L; Russo, C; Kondratova, M; Dutreix, M; Barillot, E; Zinovyev, A

    2015-01-01

    Cancerogenesis is driven by mutations leading to aberrant functioning of a complex network of molecular interactions and simultaneously affecting multiple cellular functions. Therefore, the successful application of bioinformatics and systems biology methods for analysis of high-throughput data in cancer research heavily depends on availability of global and detailed reconstructions of signalling networks amenable for computational analysis. We present here the Atlas of Cancer Signalling Network (ACSN), an interactive and comprehensive map of molecular mechanisms implicated in cancer. The resource includes tools for map navigation, visualization and analysis of molecular data in the context of signalling network maps. Constructing and updating ACSN involves careful manual curation of molecular biology literature and participation of experts in the corresponding fields. The cancer-oriented content of ACSN is completely original and covers major mechanisms involved in cancer progression, including DNA repair, cell survival, apoptosis, cell cycle, EMT and cell motility. Cell signalling mechanisms are depicted in detail, together creating a seamless 'geographic-like' map of molecular interactions frequently deregulated in cancer. The map is browsable using NaviCell web interface using the Google Maps engine and semantic zooming principle. The associated web-blog provides a forum for commenting and curating the ACSN content. ACSN allows uploading heterogeneous omics data from users on top of the maps for visualization and performing functional analyses. We suggest several scenarios for ACSN application in cancer research, particularly for visualizing high-throughput data, starting from small interfering RNA-based screening results or mutation frequencies to innovative ways of exploring transcriptomes and phosphoproteomes. Integration and analysis of these data in the context of ACSN may help interpret their biological significance and formulate mechanistic hypotheses

  15. Adherence and resource use among patients treated with biologic drugs: findings from BEETLE study

    Science.gov (United States)

    Degli Esposti, Luca; Sangiorgi, Diego; Perrone, Valentina; Radice, Sonia; Clementi, Emilio; Perone, Francesco; Buda, Stefano

    2014-01-01

    Objectives Systemic administration of anti-tumor necrosis factor alpha (anti-TNF alpha) leads to an anti-inflammatory and joint protective effect in pathologies such as rheumatoid arthritis, psoriasis, and Crohn’s disease. The aim of this study was to assess adherence to therapy, persistence in treatment (no switches or interruptions), and consumption of care resources (drugs, outpatient services, hospitalizations). Methods We conducted an observational retrospective cohort analysis using the administrative databases of five local health units. Patients filling at least one prescription for anti-TNF alpha between January 1, 2009 and December 31, 2011 were included and followed up for 1 year. Patients were defined as adherent if >80% of the follow-up period was covered by drugs dispensation. Results A total of 1,219 patients were analyzed (mean age 49.6±14.6, male 47%). Among enrolled patients, 36% were affected by rheumatoid arthritis, and 31% and 10% were affected by psoriasis and Crohn’s disease, respectively; other indications remained below these percentages. Thirty-four percent of patients (420) were treated with adalimumab, 51% (615) with etanercept, and 15% (184) with infliximab. Among the 94% of patients who did not switch, those treated with infliximab had a higher rate of adherence across all indications (51% overall) when compared to that observed in patients treated with etanercept (27%) or adalimumab (23%). The mean annual nonpharmacological expenditure for each patient in analysis was €988 for adherent and €1,255 for nonadherent patients. Infliximab was associated with the lowest cost for all indications as determined by the multivariate generalized linear model. Conclusions Patients treated with infliximab were associated with higher adherence and persistence in treatment and lower costs, as compared to those treated with adalimumab or etanercept. PMID:25258545

  16. Adherence and resource use among patients treated with biologic drugs: findings from BEETLE study

    Directory of Open Access Journals (Sweden)

    Degli Esposti L

    2014-09-01

    Full Text Available Luca Degli Esposti,1 Diego Sangiorgi,1 Valentina Perrone,2 Sonia Radice,2 Emilio Clementi,3,4 Francesco Perone,4,5 Stefano Buda1 1CliCon Srl Health, Economics and Outcomes Research, Ravenna, Italy; 2Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, L Sacco University Hospital, Università di Milano, Milan, Italy; 3Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, CNR Institute of Neuroscience, L Sacco University Hospital, Università di Milano, Milan, Italy; 4Scientific Institute, IRCCS E Medea, Lecco, Italy; 5Local Health Unit, Caserta, Italy Objectives: Systemic administration of anti-tumor necrosis factor alpha (anti-TNF alpha leads to an anti-inflammatory and joint protective effect in pathologies such as rheumatoid arthritis, psoriasis, and Crohn's disease. The aim of this study was to assess adherence to therapy, persistence in treatment (no switches or interruptions, and consumption of care resources (drugs, outpatient services, hospitalizations. Methods: We conducted an observational retrospective cohort analysis using the administrative databases of five local health units. Patients filling at least one prescription for anti-TNF alpha between January 1, 2009 and December 31, 2011 were included and followed up for 1 year. Patients were defined as adherent if >80% of the follow-up period was covered by drugs dispensation. Results: A total of 1,219 patients were analyzed (mean age 49.6±14.6, male 47%. Among enrolled patients, 36% were affected by rheumatoid arthritis, and 31% and 10% were affected by psoriasis and Crohn's disease, respectively; other indications remained below these percentages. Thirty-four percent of patients (420 were treated with adalimumab, 51% (615 with etanercept, and 15% (184 with infliximab. Among the 94% of patients who did not switch, those treated with infliximab had a higher rate of adherence across all indications (51% overall when compared to that

  17. Branching processes in disease epidemics

    Science.gov (United States)

    Singh, Sarabjeet

    Branching processes have served as a model for chemical reactions, biological growth processes and contagion (of disease, information or fads). Through this connection, these seemingly different physical processes share some common universalities that can be elucidated by analyzing the underlying branching process. In this thesis, we focus on branching processes as a model for infectious diseases spreading between individuals belonging to different populations. The distinction between populations can arise from species separation (as in the case of diseases which jump across species) or spatial separation (as in the case of disease spreading between farms, cities, urban centers, etc). A prominent example of the former is zoonoses -- infectious diseases that spill from animals to humans -- whose specific examples include Nipah virus, monkeypox, HIV and avian influenza. A prominent example of the latter is infectious diseases of animals such as foot and mouth disease and bovine tuberculosis that spread between farms or cattle herds. Another example of the latter is infectious diseases of humans such as H1N1 that spread from one city to another through migration of infectious hosts. This thesis consists of three main chapters, an introduction and an appendix. The introduction gives a brief history of mathematics in modeling the spread of infectious diseases along with a detailed description of the most commonly used disease model -- the Susceptible-Infectious-Recovered (SIR) model. The introduction also describes how the stochastic formulation of the model reduces to a branching process in the limit of large population which is analyzed in detail. The second chapter describes a two species model of zoonoses with coupled SIR processes and proceeds into the calculation of statistics pertinent to cross species infection using multitype branching processes. The third chapter describes an SIR process driven by a Poisson process of infection spillovers. This is posed as a

  18. Materials Test Branch

    Science.gov (United States)

    Gordon, Gail

    2012-01-01

    The Materials Test Branch resides at Marshall Space Flight Center's Materials and Processing laboratory and has a long history of supporting NASA programs from Mercury to the recently retired Space Shuttle. The Materials Test Branch supports its customers by supplying materials testing expertise in a wide range of applications. The Materials Test Branch is divided into three Teams, The Chemistry Team, The Tribology Team and the Mechanical Test Team. Our mission and goal is to provide world-class engineering excellence in materials testing with a special emphasis on customer service.

  19. Invasive Species Science Branch: research and management tools for controlling invasive species

    Science.gov (United States)

    Reed, Robert N.; Walters, Katie D.

    2015-01-01

    Invasive, nonnative species of plants, animals, and disease organisms adversely affect the ecosystems they enter. Like “biological wildfires,” they can quickly spread and affect nearly all terrestrial and aquatic ecosystems. Invasive species have become one of the greatest environmental challenges of the 21st century in economic, environmental, and human health costs, with an estimated effect in the United States of more than $120 billion per year. Managers of the Department of the Interior and other public and private lands often rank invasive species as their top resource management problem. The Invasive Species Science Branch of the Fort Collins Science Center provides research and technical assistance relating to management concerns for invasive species, including understanding how these species are introduced, identifying areas vulnerable to invasion, forecasting invasions, and developing control methods. To disseminate this information, branch scientists are developing platforms to share invasive species information with DOI cooperators, other agency partners, and the public. From these and other data, branch scientists are constructing models to understand and predict invasive species distributions for more effective management. The branch also has extensive herpetological and population biology expertise that is applied to harmful reptile invaders such as the Brown Treesnake on Guam and Burmese Python in Florida.

  20. Koenigs function and branching processes

    CERN Document Server

    Chikilev, O G

    2001-01-01

    An explicit solution of time-homogeneous pure birth branching processes is described. It gives alternative extensions for the negative binomial distribution (branching processes with immigration) and for the Furry-Yule distribution (branching processes without immigration).

  1. Mathematical methods in biology and neurobiology

    CERN Document Server

    Jost, Jürgen

    2014-01-01

    Mathematical models can be used to meet many of the challenges and opportunities offered by modern biology. The description of biological phenomena requires a range of mathematical theories. This is the case particularly for the emerging field of systems biology. Mathematical Methods in Biology and Neurobiology introduces and develops these mathematical structures and methods in a systematic manner. It studies:   • discrete structures and graph theory • stochastic processes • dynamical systems and partial differential equations • optimization and the calculus of variations.   The biological applications range from molecular to evolutionary and ecological levels, for example:   • cellular reaction kinetics and gene regulation • biological pattern formation and chemotaxis • the biophysics and dynamics of neurons • the coding of information in neuronal systems • phylogenetic tree reconstruction • branching processes and population genetics • optimal resource allocation • sexual recombi...

  2. Active Learning in a Large First Year Biology Class: A Collaborative Resource-Based Study Project on "AIDS in Science and Society".

    Science.gov (United States)

    Sutcliffe, Roger G.; Cogdell, Barbara; Hansell, Mike H.; McAteer, Erica

    1999-01-01

    Describes a student-directed learning program called "AIDS in Science and Society" that was developed as a resource-based, collaborative project at the University of Glasgow (United Kingdom) for a first-year biology class. Discusses materials, written assignments, oral presentations, and feedback from students and faculty, and includes a list of…

  3. Synthesis of branched polysaccharides with tunable degree of branching

    NARCIS (Netherlands)

    Ciric, Jelena; Loos, Katja

    2013-01-01

    An in vitro enzyme-catalyzed tandem reaction using the enzymes phosphorylase b from rabbit muscle and Deinococcus geothermalis glycogen branching enzyme (Dg GBE) to obtain branched polyglucans with tunable degree of branching (2% divided by 13%) is presented. The tunable degree of branching is obtai

  4. Fuzzy branching temporal logic.

    Science.gov (United States)

    Moon, Seong-ick; Lee, Kwang H; Lee, Doheon

    2004-04-01

    Intelligent systems require a systematic way to represent and handle temporal information containing uncertainty. In particular, a logical framework is needed that can represent uncertain temporal information and its relationships with logical formulae. Fuzzy linear temporal logic (FLTL), a generalization of propositional linear temporal logic (PLTL) with fuzzy temporal events and fuzzy temporal states defined on a linear time model, was previously proposed for this purpose. However, many systems are best represented by branching time models in which each state can have more than one possible future path. In this paper, fuzzy branching temporal logic (FBTL) is proposed to address this problem. FBTL adopts and generalizes concurrent tree logic (CTL*), which is a classical branching temporal logic. The temporal model of FBTL is capable of representing fuzzy temporal events and fuzzy temporal states, and the order relation among them is represented as a directed graph. The utility of FBTL is demonstrated using a fuzzy job shop scheduling problem as an example. PMID:15376850

  5. Right bundle branch block

    DEFF Research Database (Denmark)

    Bussink, Barbara E; Holst, Anders Gaarsdal; Jespersen, Lasse;

    2013-01-01

    AimsTo determine the prevalence, predictors of newly acquired, and the prognostic value of right bundle branch block (RBBB) and incomplete RBBB (IRBBB) on a resting 12-lead electrocardiogram in men and women from the general population.Methods and resultsWe followed 18 441 participants included.......5%/2.3% in women, P Right bundle branch block was associated with significantly...... increased all-cause and cardiovascular mortality in both genders with age-adjusted hazard ratios (HR) of 1.31 [95% confidence interval (CI), 1.11-1.54] and 1.87 (95% CI, 1.48-2.36) in the gender pooled analysis with little attenuation after multiple adjustment. Right bundle branch block was associated...

  6. Big Branch Marsh National Wildlife Refuge Habitat Management Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Big Branch National Wildlife Refuge Habitat Management Plan provides a long-term vision and specific guidance on managing habitats for the resources of concern...

  7. Building the Digital Branch A Library Technology Report

    CERN Document Server

    King, David Lee

    2009-01-01

    This issue of Library Technology Reports explores the idea of the digital branch-a library website that is a vital, functional resource for patrons and enhances the library's place within its community.

  8. Branching process models of cancer

    CERN Document Server

    Durrett, Richard

    2015-01-01

    This volume develops results on continuous time branching processes and applies them to study rate of tumor growth, extending classic work on the Luria-Delbruck distribution. As a consequence, the authors calculate the probability that mutations that confer resistance to treatment are present at detection and quantify the extent of tumor heterogeneity. As applications, the authors evaluate ovarian cancer screening strategies and give rigorous proofs for results of Heano and Michor concerning tumor metastasis. These notes should be accessible to students who are familiar with Poisson processes and continuous time. Richard Durrett is mathematics professor at Duke University, USA. He is the author of 8 books, over 200 journal articles, and has supervised more than 40 Ph.D. students. Most of his current research concerns the applications of probability to biology: ecology, genetics, and most recently cancer.

  9. Radioiodinated branched carbohydrates

    Science.gov (United States)

    Goodman, Mark M.; Knapp, Jr., Furn F.

    1989-01-01

    A radioiodinated branched carbohydrate for tissue imaging. Iodine-123 is stabilized in the compound by attaching it to a vinyl functional group that is on the carbohydrate. The compound exhibits good uptake and retention and is promising in the development of radiopharmaceuticals for brain, heart and tumor imaging.

  10. Tracheobronchial Branching Anomalies

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Min Ji; Kim, Young Tong; Jou, Sung Shick [Soonchunhyang University, Cheonan Hospital, Cheonan (Korea, Republic of); Park, A Young [Soonchunhyang University College of Medicine, Asan (Korea, Republic of)

    2010-04-15

    There are various congenital anomalies with respect to the number, length, diameter, and location of tracheobronchial branching patterns. The tracheobronchial anomalies are classified into two groups. The first one, anomalies of division, includes tracheal bronchus, cardiac bronchus, tracheal diverticulum, pulmonary isomerism, and minor variations. The second one, dysmorphic lung, includes lung agenesis-hypoplasia complex and lobar agenesis-aplasia complex

  11. Multimode geodesic branching components

    Science.gov (United States)

    Schulz, D.; Voges, E.

    1983-01-01

    Geodesic branching components are investigated for multimode guided wave optics. Geodesic structures with particular properties, e.g. focussing star couplers, are derived by a synthesis technique based on a theorem of Toraldo di Francia. Experimentally, the geodesic surfaces are printed on acrylic glass and are spin-coated with organic film waveguides.

  12. 麻疯树枝枯病病原鉴定及生物学特性测定%Identification on Pathogen of Branch Rot of Jatropha curcas and Study on Its Biological Characteristics

    Institute of Scientific and Technical Information of China (English)

    付文; 伍建榕; 马桂平; 扎史茨姆; 刘育红; 马焕成; 胥辉

    2011-01-01

    In order to identify the pathogeny and pathogenicity of branch rot of Jatropha curcas. Branch rot of Jatropha curcas caused by Lasdiplodia theobroma was reported, illustrated and literal description was given in detail based on the materials from Yuanmo, Yunnan in China. Morphological and molecular data were taken into consideration when the pathogen was authenticated. In view of available references, the author thought that was the first report about it. The author gained some results after finished the study about the biological characters of pathogen, pathogen grow actively in the condition of 28-30℃, pH=5-7, the culture medium with CsH12O6, C12H24O12. yeast powder. Sporegermination was more active in the condition of 20-30℃, pH=6,humidity (90%-100%), sterile water. It can produce a few spore and spore apparatus under light. Mycelial growth was significantly inhibited in PDA plate which contained Propiconazol Carbendazim, at the same time,the interesting phenomenon was found that mycelial was fast growing in the PDA plate which contained Dffenoconazole, Streptomycin, Chlorothalonil, Ethylicin, Propiconazole, etc. That was like in the PDA plate.The author thought this disease was rampant when hosts were wounded and ecology environment was high humidity based on analyzing biological nature of pathogen and ecology environment of host. After that the author had some good ideas about disease prevention and cure which disease should mainly be prevented and the use of pesticides scientifically must be adopted.%为了确定麻疯树枝枯病的病原及致病性,笔者通过形态和分子的方法鉴定出麻疯树枝枯病病原菌为Lasiodiplodia theobroma,查阅分析相关资料发现其是一种新病害,因此采用文字和插图方法对痛害进行详细描述.结果表明,引起麻疯树枝枯病的病原为Lasiodiplodia theobroma,在此基础上完成病原菌生物学特性测定,发现病原菌是一种弱致病性真菌,在温度为28~30%

  13. Patterns of database citation in articles and patents indicate long-term scientific and industry value of biological data resources [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    David Bousfield

    2016-02-01

    Full Text Available Data from open access biomolecular data resources, such as the European Nucleotide Archive and the Protein Data Bank are extensively reused within life science research for comparative studies, method development and to derive new scientific insights. Indicators that estimate the extent and utility of such secondary use of research data need to reflect this complex and highly variable data usage. By linking open access scientific literature, via Europe PubMedCentral, to the metadata in biological data resources we separate data citations associated with a deposition statement from citations that capture the subsequent, long-term, reuse of data in academia and industry.  We extend this analysis to begin to investigate citations of biomolecular resources in patent documents. We find citations in more than 8,000 patents from 2014, demonstrating substantial use and an important role for data resources in defining biological concepts in granted patents to both academic and industrial innovators. Combined together our results indicate that the citation patterns in biomedical literature and patents vary, not only due to citation practice but also according to the data resource cited. The results guard against the use of simple metrics such as citation counts and show that indicators of data use must not only take into account citations within the biomedical literature but also include reuse of data in industry and other parts of society by including patents and other scientific and technical documents such as guidelines, reports and grant applications.

  14. Geometry optimization of branchings in vascular networks

    Science.gov (United States)

    Khamassi, Jamel; Bierwisch, Claas; Pelz, Peter

    2016-06-01

    Progress has been made in developing manufacturing technologies which enable the fabrication of artificial vascular networks for tissue cultivation. However, those networks are rudimentary designed with respect to their geometry. This restricts long-term biological functionality of vascular cells which depends on geometry-related fluid mechanical stimuli and the avoidance of vessel occlusion. In the present work, a bioinspired geometry optimization for branchings in artificial vascular networks has been conducted. The analysis could be simplified by exploiting self-similarity properties of the system. Design rules in the form of two geometrical parameters, i.e., the branching angle and the radius ratio of the daughter branches, are derived using the wall shear stress as command variable. The numerical values of these parameters are within the range of experimental observations. Those design rules are not only beneficial for tissue engineering applications. Moreover, they can be used as indicators for diagnoses of vascular diseases or for the layout of vascular grafts.

  15. Electrochemical Energy Storage Branch

    Science.gov (United States)

    1985-01-01

    The activities of the Electrochemical Energy Storage Branch are highlighted, including the Technology Base Research and the Exploratory Technology Development and Testing projects within the Electrochemical Energy Storage Program for the 1984 fiscal year. General Headquarters activities are presented first; and then, a summary of the Director Controlled Milestones, followed by other major accomplishments. A listing of the workshops and seminars held during the year is also included.

  16. Tau leptonic branching ratios

    CERN Document Server

    Buskulic, Damir; De Bonis, I; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Odier, P; Pietrzyk, B; Ariztizabal, F; Chmeissani, M; Crespo, J M; Efthymiopoulos, I; Fernández, E; Fernández-Bosman, M; Gaitan, V; Garrido, L; Martínez, M; Orteu, S; Pacheco, A; Padilla, C; Palla, Fabrizio; Pascual, A; Perlas, J A; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Farilla, A; Gelao, G; Girone, M; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Natali, S; Nuzzo, S; Ranieri, A; Raso, G; Romano, F; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Bonvicini, G; Cattaneo, M; Comas, P; Coyle, P; Drevermann, H; Engelhardt, A; Forty, Roger W; Frank, M; Hagelberg, R; Harvey, J; Jacobsen, R; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Markou, C; Martin, E B; Mato, P; Minten, Adolf G; Miquel, R; Oest, T; Palazzi, P; Pater, J R; Pusztaszeri, J F; Ranjard, F; Rensing, P E; Rolandi, Luigi; Schlatter, W D; Schmelling, M; Schneider, O; Tejessy, W; Tomalin, I R; Venturi, A; Wachsmuth, H W; Wiedenmann, W; Wildish, T; Witzeling, W; Wotschack, J; Ajaltouni, Ziad J; Bardadin-Otwinowska, Maria; Barrès, A; Boyer, C; Falvard, A; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rossignol, J M; Saadi, F; Fearnley, Tom; Hansen, J B; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Kyriakis, A; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Zachariadou, K; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Passalacqua, L; Rougé, A; Rumpf, M; Tanaka, R; Valassi, Andrea; Verderi, M; Videau, H L; Candlin, D J; Parsons, M I; Focardi, E; Parrini, G; Corden, M; Delfino, M C; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Pepé-Altarelli, M; Dorris, S J; Halley, A W; ten Have, I; Knowles, I G; Lynch, J G; Morton, W T; O'Shea, V; Raine, C; Reeves, P; Scarr, J M; Smith, K; Smith, M G; Thompson, A S; Thomson, F; Thorn, S; Turnbull, R M; Becker, U; Braun, O; Geweniger, C; Graefe, G; Hanke, P; Hepp, V; Kluge, E E; Putzer, A; Rensch, B; Schmidt, M; Sommer, J; Stenzel, H; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Colling, D J; Dornan, Peter J; Konstantinidis, N P; Moneta, L; Moutoussi, A; Nash, J; San Martin, G; Sedgbeer, J K; Stacey, A M; Dissertori, G; Girtler, P; Kuhn, D; Rudolph, G; Bowdery, C K; Brodbeck, T J; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Sloan, Terence; Whelan, E P; Williams, M I; Galla, A; Greene, A M; Kleinknecht, K; Quast, G; Raab, J; Renk, B; Sander, H G; Wanke, R; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Bencheikh, A M; Benchouk, C; Bonissent, A; Bujosa, G; Calvet, D; Carr, J; Diaconu, C A; Etienne, F; Thulasidas, M; Nicod, D; Payre, P; Rousseau, D; Talby, M; Abt, I; Assmann, R W; Bauer, C; Blum, Walter; Brown, D; Dietl, H; Dydak, Friedrich; Ganis, G; Gotzhein, C; Jakobs, K; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Wolf, G; Alemany, R; Boucrot, J; Callot, O; Cordier, A; Courault, F; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Jacquet, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Musolino, G; Nikolic, I A; Park, H J; Park, I C; Schune, M H; Simion, S; Veillet, J J; Videau, I; Abbaneo, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Rizzo, G; Sanguinetti, G; Sciabà, A; Spagnolo, P; Steinberger, Jack; Tenchini, Roberto; Tonelli, G; Triggiani, G; Vannini, C; Verdini, P G; Walsh, J; Betteridge, A P; Blair, G A; Bryant, L M; Cerutti, F; Gao, Y; Green, M G; Johnson, D L; Medcalf, T; Mir, L M; Perrodo, P; Strong, J A; Bertin, V; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Edwards, M; Maley, P; Norton, P R; Thompson, J C; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Marx, B; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Johnson, R P; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Beddall, A; Booth, C N; Boswell, R; Cartwright, S L; Combley, F; Dawson, I; Köksal, A; Letho, M; Newton, W M; Rankin, C; Thompson, L F; Böhrer, A; Brandt, S; Cowan, G D; Feigl, E; Grupen, Claus; Lutters, G; Minguet-Rodríguez, J A; Rivera, F; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Ragusa, F; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Bellantoni, L; Elmer, P; Feng, Z; Ferguson, D P S; Gao, Y S; González, S; Grahl, J; Harton, J L; Hayes, O J; Hu, H; McNamara, P A; Nachtman, J M; Orejudos, W; Pan, Y B; Saadi, Y; Schmitt, M; Scott, I J; Sharma, V; Turk, J; Walsh, A M; Wu Sau Lan; Wu, X; Yamartino, J M; Zheng, M; Zobernig, G

    1996-01-01

    A sample of 62249 \\tau-pair events is selected from data taken with the ALEPH detector in 1991, 1992 and 1993. The measurement of the branching fractions for \\tau decays into electrons and muons is presented with emphasis on the study of systematic effects from selection, particle identification and decay classification. Combined with the most recent ALEPH determination of the \\tau lifetime, these results provide a relative measurement of the leptonic couplings in the weak charged current for transverse W bosons.

  17. Hawaii Geothermal Project annotated bibliography: Biological resources of the geothermal subzones, the transmission corridors and the Puna District, Island of Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Miller, S.E.; Burgett, J.M. [Fish and Wildlife Service, Honolulu, HI (United States). Pacific Islands Office

    1993-10-01

    Task 1 of the Hawaii Geothermal Project Interagency Agreement between the Fish and Wildlife Service and the Department of Energy-Oak Ridge National Laboratory (DOE) includes an annotated bibliography of published and unpublished documents that cover biological issues related to the lowland rain forest in Puna, adjacent areas, transmission corridors, and in the proposed Hawaii Geothermal Project (HGP). The 51 documents reviewed in this report cover the main body of biological information for these projects. The full table of contents and bibliography for each document is included along with two copies (as requested in the Interagency Agreement) of the biological sections of each document. The documents are reviewed in five main categories: (1) geothermal subzones (29 documents); (2) transmission cable routes (8 documents); (3) commercial satellite launching facility (Spaceport; 1 document); (4) manganese nodule processing facility (2 documents); (5) water resource development (1 document); and (6) ecosystem stability and introduced species (11 documents).

  18. Control structure design for resource recovery using the enhanced biological phosphorus removal and recovery (EBP2R) activated sludge process

    DEFF Research Database (Denmark)

    Valverde Perez, Borja; Fuentes-Martínez, José Manuel; Flores Alsina, Xavier;

    2016-01-01

    Nowadays, wastewater is considered as a set of resources to be recovered rather than a mixture of pollutantsthat should be removed. Many resource recovery schemes have been proposed, involving the useof novel technologies whose controllability is poorly studied. In this paper we present a control...

  19. Thermal Energy Conversion Branch

    Science.gov (United States)

    Bielozer, Matthew C.; Schreiber, Jeffrey, G.; Wilson, Scott D.

    2004-01-01

    The Thermal Energy Conversion Branch (5490) leads the way in designing, conducting, and implementing research for the newest thermal systems used in space applications at the NASA Glenn Research Center. Specifically some of the most advanced technologies developed in this branch can be broken down into four main areas: Dynamic Power Systems, Primary Solar Concentrators, Secondary Solar Concentrators, and Thermal Management. Work was performed in the Dynamic Power Systems area, specifically the Stirling Engine subdivision. Today, the main focus of the 5490 branch is free-piston Stirling cycle converters, Brayton cycle nuclear reactors, and heat rejection systems for long duration mission spacecraft. All space exploring devices need electricity to operate. In most space applications, heat energy from radioisotopes is converted to electrical power. The Radioisotope Thermoelectric Generator (RTG) already supplies electricity for missions such as the Cassini Spacecraft. The focus of today's Stirling research at GRC is aimed at creating an engine that can replace the RTG. The primary appeal of the Stirling engine is its high system efficiency. Because it is so efficient, the Stirling engine will significantly reduce the plutonium fuel mission requirements compared to the RTG. Stirling is also being considered for missions such as the lunar/Mars bases and rovers. This project has focused largely on Stirling Engines of all types, particularly the fluidyne liquid piston engine. The fluidyne was developed by Colin D. West. This engine uses the same concepts found in any type of Stirling engine, with the exception of missing mechanical components. All the working components are fluid. One goal was to develop and demonstrate a working Stirling Fluidyne Engine at the 2nd Annual International Energy Conversion Engineering Conference in Providence, Rhode Island.

  20. Combustion Branch Website Development

    Science.gov (United States)

    Bishop, Eric

    2004-01-01

    The NASA combustion branch is a leader in developing and applying combustion science to focused aerospace propulsion systems concepts. It is widely recognized for unique facilities, analytical tools, and personnel. In order to better communicate the outstanding research being done in this Branch to the public and other research organization, a more substantial website was desired. The objective of this project was to build an up-to-date site that reflects current research in a usable and attractive manner. In order to accomplish this, information was requested from all researchers in the Combustion branch, on their professional skills and on the current projects. This information was used to fill in the Personnel and Research sections of the website. A digital camera was used to photograph all personnel and these photographs were included in the personnel section as well. The design of the site was implemented using the latest web standards: xhtml and external css stylesheets. This implementation conforms to the guidelines recommended by the w3c. It also helps to ensure that the web site is accessible by disabled users, and complies with Section 508 Federal legislation (which mandates that all Federal websites be accessible). Graphics for the new site were generated using the gimp (www.gimp.org) an open-source graphics program similar to Adobe Photoshop. Also, all graphics on the site were of a reasonable size (less than 20k, most less than 2k) so that the page would load quickly. Technologies such as Macromedia Flash and Javascript were avoided, as these only function on some clients which have the proper software installed or enabled. The website was tested on different platforms with many different browsers to ensure there were no compatibility issues. The website was tested on windows with MS IE 6, MSIE 5 , Netscape 7, Mozilla and Opera. On a Mac, the site was tested with MS IE 5 , Netscape 7 and Safari.

  1. Branch formation during organ development

    Science.gov (United States)

    Gjorevski, Nikolce; Nelson, Celeste M.

    2010-01-01

    Invertebrates and vertebrates use branching morphogenesis to build epithelial trees to maximize the surface area of organs within a given volume. Several molecular regulators of branching have recently been discovered, a number of which are conserved across different organs and species. Signals that control branching at the cellular and tissue levels are also starting to emerge, and are rapidly unveiling the physical nature of branch development. Here we discuss the molecular, cellular and physical processes that govern branch formation and highlight the major outstanding questions in the field. PMID:20890968

  2. Anomalous scaling in an age-dependent branching model

    OpenAIRE

    Keller-Schmidt, Stephanie; Tugrul, Murat; Eguíluz, Víctor M.; Hernández-García, Emilio; Klemm, Konstantin

    2015-01-01

    We introduce a one-parametric family of tree growth models, in which branching probabilities decrease with branch age $\\tau$ as $\\tau^{-\\alpha}$. Depending on the exponent $\\alpha$, the scaling of tree depth with tree size $n$ displays a transition between the logarithmic scaling of random trees and an algebraic growth. At the transition ($\\alpha=1$) tree depth grows as $(\\log n)^2$. This anomalous scaling is in good agreement with the trend observed in evolution of biological species, thus p...

  3. Anomalous scaling in an age-dependent branching model

    OpenAIRE

    Keller-Schmidt, Stephanie; Tugrul, Murat; Eguiluz, Victor M.; Hernandez-Garcia, Emilio; Klemm, Konstantin

    2010-01-01

    We introduce a one-parametric family of tree growth models, in which branching probabilities decrease with branch age $\\tau$ as $\\tau^{-\\alpha}$. Depending on the exponent $\\alpha$, the scaling of tree depth with tree size $n$ displays a transition between the logarithmic scaling of random trees and an algebraic growth. At the transition ($\\alpha=1$) tree depth grows as $(\\log n)^2$. This anomalous scaling is in good agreement with the trend observed in evolution of biological species, thus p...

  4. Path-valued branching processes and nonlocal branching superprocesses

    CERN Document Server

    Li, Zenghu

    2012-01-01

    A family of continuous-state branching processes with immigration are constructed as the solution flow of a stochastic equation system driven by time-space noises. The family can be regarded as an inhomogeneous increasing path-valued branching process with immigration. Two nonlocal branching immigration superprocesses can be defined from the flow. We identify explicitly the branching and immigration mechanisms of those processes. The results provide new perspectives into the tree-valued Markov processes of Aldous and Pitman [Ann. Inst. H. Poincare Probab. Statist. 34 (1998), 637--686] and Abraham and Delmas [Ann. Probab. To appear].

  5. Quiver Varieties and Branching

    Directory of Open Access Journals (Sweden)

    Hiraku Nakajima

    2009-01-01

    Full Text Available Braverman and Finkelberg recently proposed the geometric Satake correspondence for the affine Kac-Moody group Gaff [Braverman A., Finkelberg M., arXiv:0711.2083]. They conjecture that intersection cohomology sheaves on the Uhlenbeck compactification of the framed moduli space of Gcpt-instantons on $R^4/Z_r$ correspond to weight spaces of representations of the Langlands dual group $G_{aff}^{vee}$ at level $r$. When $G = SL(l$, the Uhlenbeck compactification is the quiver variety of type $sl(r_{aff}$, and their conjecture follows from the author's earlier result and I. Frenkel's level-rank duality. They further introduce a convolution diagram which conjecturally gives the tensor product multiplicity [Braverman A., Finkelberg M., Private communication, 2008]. In this paper, we develop the theory for the branching in quiver varieties and check this conjecture for $G = SL(l$.

  6. Methods and Technologies Branch (MTB)

    Science.gov (United States)

    The Methods and Technologies Branch focuses on methods to address epidemiologic data collection, study design and analysis, and to modify technological approaches to better understand cancer susceptibility.

  7. Profile of social, environmental and biological correlates in intellectual disability in a resource-poor setting in India

    Directory of Open Access Journals (Sweden)

    Ram Lakhan

    2015-01-01

    Full Text Available Background: Intellectual disability (ID is a major public health issue in India. Social, environmental and biological factors all contribute to the nation′s high rate of ID. Objective: We aimed to investigate the distribution, differences and the association of social, environmental and biological factors with different types of ID in a mixed (tribal and non-tribal population in India. Materials and Methods: Secondary data was collected during a community-based rehabilitation project and analyzed with descriptive statistics: Frequency, percentage and χ2 . Results: Poverty, low levels of parental education and a family history of epilepsy and ID were all associated in both tribal and non-tribal populations (P < 0.05. Conclusion: The outcome of this study may be helpful in planning public health initiatives that aim to reduce the burden of ID in mixed populations.

  8. Sequence-related amplified polymorphism (SRAP) markers: A potential resource for studies in plant molecular biology1

    OpenAIRE

    Robarts, Daniel W. H.; Wolfe, Andrea D.

    2014-01-01

    In the past few decades, many investigations in the field of plant biology have employed selectively neutral, multilocus, dominant markers such as inter-simple sequence repeat (ISSR), random-amplified polymorphic DNA (RAPD), and amplified fragment length polymorphism (AFLP) to address hypotheses at lower taxonomic levels. More recently, sequence-related amplified polymorphism (SRAP) markers have been developed, which are used to amplify coding regions of DNA with primers targeting open readin...

  9. Behavioral externalities in natural resource production possibility frontiers: integrating biology and economics to model human-wildlife interactions.

    Science.gov (United States)

    McCoy, N H

    2003-09-01

    Production possibility modeling has been applied to a variety of wildlife management issues. Although it has seen only limited employment in modeling human-wildlife output decisions, it can be expected that the theory's use in this area will increase as human interactions with and impacts on wildlife become more frequent. At present, most models applying production possibility theory to wildlife production can be characterized in that wildlife output quantities are determined by physically quantifiable functions representing rivalrous resources. When the theory is applied to human-wildlife interactions, it may not be sufficient to model the production tradeoffs using only physical constraints. As wildlife are known to respond to human presence, it could be expected that human activity may appear in wildlife production functions as an externality. Behavioral externalities are revealed by an output's response to the presence of another output and can result in a loss of concavity of the production possibilities frontier. Ignoring the potential of a behavioral externality can result in an unexpected and inefficient output allocation that may compromise a wildlife population's well-being. Behavioral externalities can be included in PPF models in a number of ways, including the use of data or cumulative effects modeling. While identifying that behavioral externalities exist and incorporating them into a model is important, correctly interpreting their implications will be critical to improve the efficiency of natural resource management. Behavioral externalities may cause a loss of concavity anywhere along a PPF that may compel managerial decisions that are inconsistent with multiple use doctrines. Convex PPFs may result when wildlife species are extremely sensitive to any level of human activity. It may be possible to improve the PPF's concavity by reducing the strength of the behavioral effect. Any change in the PPF that increases the convexity of the production set

  10. Sand Dredging and River Morphology Change along Parts of New Calabar River in Akpor Area of Rivers State, Nigeria and its Implications for Biological Resource Conservation

    Directory of Open Access Journals (Sweden)

    P.C. Mmom

    2012-01-01

    Full Text Available The study was instituted to assess the impact of sand dredging along parts of New Calabar River channel morphology and the implication for biological resources conservation.The study was conducted within a period of two years (2008 and 2009 in two major sand dredging sites (Ogbogoro and Rumuorlumeni areas along the new Calabar River in Rivers State, Nigeria. The channel measurement was ascertained using hydrographic survey report carried out by dredge operators in the areas. The influence of river channel incision on river hydraulics was evaluated by comparing stream velocity of the different years. The volume of sand in the two areas were ascertained from sand search report, sediment lost from the channel were also obtained from the dredge time reports of dredge operators. The study reveals thatsignificant down-cutting in the riverbed along these parts of the New Calabar River. Significant increase in stream velocity was observed with increase the sediment transport capacityand accelerated channel incision; in fact there was significant change in the channel geometry. Consequently, there was an observed decline in the productivity of aquatic resources in the area, which our survey affirms as being a result of intense sand dredging in the area. The study therefore concludes that intense and uncontrolled sand dredging in the study area would mean detrimental impact on river management systems as well as future of the aquatic biodiversity and biological resources in the area. Thus, there is need for stringent restrictions on in-channel sand mining to save the biophysical and socio-economic environment of the affected areas.

  11. Tau hadronic branching ratios

    CERN Document Server

    Buskulic, Damir; De Bonis, I; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Odier, P; Pietrzyk, B; Ariztizabal, F; Chmeissani, M; Crespo, J M; Efthymiopoulos, I; Fernández, E; Fernández-Bosman, M; Gaitan, V; Martínez, M; Orteu, S; Pacheco, A; Padilla, C; Palla, Fabrizio; Pascual, A; Perlas, J A; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Farilla, A; Gelao, G; Girone, M; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Natali, S; Nuzzo, S; Ranieri, A; Raso, G; Romano, F; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Bonvicini, G; Cattaneo, M; Comas, P; Coyle, P; Drevermann, H; Engelhardt, A; Forty, Roger W; Frank, M; Hagelberg, R; Harvey, J; Jacobsen, R; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Markou, C; Martin, E B; Mato, P; Minten, Adolf G; Miquel, R; Oest, T; Palazzi, P; Pater, J R; Pusztaszeri, J F; Ranjard, F; Rensing, P E; Rolandi, Luigi; Schlatter, W D; Schmelling, M; Schneider, O; Tejessy, W; Tomalin, I R; Venturi, A; Wachsmuth, H W; Wiedenmann, W; Wildish, T; Witzeling, W; Wotschack, J; Ajaltouni, Ziad J; Bardadin-Otwinowska, Maria; Barrès, A; Boyer, C; Falvard, A; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rossignol, J M; Saadi, F; Fearnley, Tom; Hansen, J B; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Kyriakis, A; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Zachariadou, K; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Passalacqua, L; Rougé, A; Rumpf, M; Tanaka, R; Valassi, Andrea; Verderi, M; Videau, H L; Candlin, D J; Parsons, M I; Focardi, E; Parrini, G; Corden, M; Delfino, M C; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Pepé-Altarelli, M; Dorris, S J; Halley, A W; ten Have, I; Knowles, I G; Lynch, J G; Morton, W T; O'Shea, V; Raine, C; Reeves, P; Scarr, J M; Smith, K; Smith, M G; Thompson, A S; Thomson, F; Thorn, S; Turnbull, R M; Becker, U; Braun, O; Geweniger, C; Graefe, G; Hanke, P; Hepp, V; Kluge, E E; Putzer, A; Rensch, B; Schmidt, M; Sommer, J; Stenzel, H; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Colling, D J; Dornan, Peter J; Konstantinidis, N P; Moneta, L; Moutoussi, A; Nash, J; San Martin, G; Sedgbeer, J K; Stacey, A M; Dissertori, G; Girtler, P; Kuhn, D; Rudolph, G; Bowdery, C K; Brodbeck, T J; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Sloan, Terence; Whelan, E P; Williams, M I; Galla, A; Greene, A M; Kleinknecht, K; Quast, G; Raab, J; Renk, B; Sander, H G; Wanke, R; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Bencheikh, A M; Benchouk, C; Bonissent, A; Bujosa, G; Calvet, D; Carr, J; Diaconu, C A; Etienne, F; Thulasidas, M; Nicod, D; Payre, P; Rousseau, D; Talby, M; Abt, I; Assmann, R W; Bauer, C; Blum, Walter; Brown, D; Dietl, H; Dydak, Friedrich; Ganis, G; Gotzhein, C; Jakobs, K; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Wolf, G; Alemany, R; Boucrot, J; Callot, O; Cordier, A; Courault, F; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Jacquet, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Musolino, G; Nikolic, I A; Park, H J; Park, I C; Schune, M H; Simion, S; Veillet, J J; Videau, I; Abbaneo, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Rizzo, G; Sanguinetti, G; Sciabà, A; Spagnolo, P; Steinberger, Jack; Tenchini, Roberto; Tonelli, G; Triggiani, G; Vannini, C; Verdini, P G; Walsh, J; Betteridge, A P; Blair, G A; Bryant, L M; Cerutti, F; Gao, Y; Green, M G; Johnson, D L; Medcalf, T; Mir, L M; Perrodo, P; Strong, J A; Bertin, V; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Edwards, M; Maley, P; Norton, P R; Thompson, J C; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Marx, B; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Johnson, R P; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Beddall, A; Booth, C N; Boswell, R; Cartwright, S L; Combley, F; Dawson, I; Köksal, A; Letho, M; Newton, W M; Rankin, C; Thompson, L F; Böhrer, A; Brandt, S; Cowan, G D; Feigl, E; Grupen, Claus; Lutters, G; Minguet-Rodríguez, J A; Rivera, F; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Ragusa, F; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Bellantoni, L; Elmer, P; Feng, Z; Ferguson, D P S; Gao, Y S; González, S; Grahl, J; Harton, J L; Hayes, O J; Hu, H; McNamara, P A; Nachtman, J M; Orejudos, W; Pan, Y B; Saadi, Y; Schmitt, M; Scott, I J; Sharma, V; Turk, J; Walsh, A M; Wu Sau Lan; Wu, X; Yamartino, J M; Zheng, M; Zobernig, G

    1996-01-01

    From 64492 selected \\tau-pair events, produced at the Z^0 resonance, the measurement of the tau decays into hadrons from a global analysis using 1991, 1992 and 1993 ALEPH data is presented. Special emphasis is given to the reconstruction of photons and \\pi^0's, and the removal of fake photons. A detailed study of the systematics entering the \\pi^0 reconstruction is also given. A complete and consistent set of tau hadronic branching ratios is presented for 18 exclusive modes. Most measurements are more precise than the present world average. The new level of precision reached allows a stringent test of \\tau-\\mu universality in hadronic decays, g_\\tau/g_\\mu \\ = \\ 1.0013 \\ \\pm \\ 0.0095, and the first measurement of the vector and axial-vector contributions to the non-strange hadronic \\tau decay width: R_{\\tau ,V} \\ = \\ 1.788 \\ \\pm \\ 0.025 and R_{\\tau ,A} \\ = \\ 1.694 \\ \\pm \\ 0.027. The ratio (R_{\\tau ,V} - R_{\\tau ,A}) / (R_{\\tau ,V} + R_{\\tau ,A}), equal to (2.7 \\pm 1.3) \\ \\%, is a measure of the importance of Q...

  12. Integrated Modeling System for Analysis of Watershed Water Balance: A Case Study in the Tims Branch Watershed, South Carolina

    Science.gov (United States)

    Setegn, S. G.; Mahmoudi, M.; Lawrence, A.; Duque, N.

    2015-12-01

    The Applied Research Center at Florida International University (ARC-FIU) is supporting the soil and groundwater remediation efforts of the U.S. Department of Energy (DOE) Savannah River Site (SRS) by developing a surface water model to simulate the hydrology and the fate and transport of contaminants and sediment in the Tims Branch watershed. Hydrological models are useful tool in water and land resource development and decision-making for watershed management. Moreover, simulation of hydrological processes improves understanding of the environmental dynamics and helps to manage and protect water resources and the environment. MIKE SHE, an advanced integrated modeling system is used to simulate the hydrological processes of the Tim Branch watershed with the objective of developing an integrated modeling system to improve understanding of the physical, chemical and biological processes within the Tims Branch watershed. MIKE SHE simulates water flow in the entire land based phase of the hydrological cycle from rainfall to river flow, via various flow processes such as, overland flow, infiltration, evapotranspiration, and groundwater flow. In this study a MIKE SHE model is developed and applied to the Tim branch watershed to study the watershed response to storm events and understand the water balance of the watershed under different climatic and catchment characteristics. The preliminary result of the integrated model indicated that variation in the depth of overland flow highly depend on the amount and distribution of rainfall in the watershed. The ultimate goal of this project is to couple the MIKE SHE and MIKE 11 models to integrate the hydrological component in the land phase of hydrological cycle and stream flow process. The coupled MIKE SHE/MIKE 11 model will further be integrated with an Ecolab module to represent a range of water quality, contaminant transport, and ecological processes with respect to the stream, surface water and groundwater in the Tims

  13. Endogenous patterns of mechanical stress are required for branching morphogenesis

    Science.gov (United States)

    Gjorevski, Nikolce; Nelson, Celeste M.

    2011-01-01

    Spatial patterning of cell behaviors establishes the regional differences within tissues that collectively develop branched organs into their characteristic treelike shapes. Here we show that the pattern of branching morphogenesis of three-dimensional (3D) engineered epithelial tissues is controlled in part by gradients of endogenous mechanical stress. We used microfabrication to build model mammary epithelial tissues of defined geometry that branched in a stereotyped pattern when induced with growth factors. Branches initiated from sites of high mechanical stress within the tissues, as predicted numerically and measured directly using 3D traction force microscopy. Branch sites were defined by activation of focal adhesion kinase (FAK), inhibition of which disrupted morphogenesis. Stress, FAK activation, and branching were all altered by manipulating cellular contractility, matrix stiffness, intercellular cohesion and tissue geometry. These data suggest that the pattern and magnitude of mechanical stress across epithelial tissues cooperate with biochemical signals to specify branching pattern. Insight, innovation, integration Morphogenesis is ultimately a physical process wherein tissues are sculpted into their final three-dimensional (3D) patterns. Mechanical stresses from the microenvironment can also play regulatory roles, but their influence on pattern is difficult to ascertain in 3D systems in vivo. Here we integrate 3D microscale engineered tissues with insight from biological mechanics to understand the role of endogenous mechanical stresses in patterning tissue development. The innovation lies in the use of numerical modeling to design experiments that can predict the stress distribution and resulting morphogenesis of model tissues. PMID:20717570

  14. Continuous-state branching processes

    CERN Document Server

    Li, Zenghu

    2012-01-01

    These notes were used in a short graduate course on branching processes the author gave in Beijing Normal University. The following main topics are covered: scaling limits of Galton--Watson processes, continuous-state branching processes, extinction probabilities, conditional limit theorems, decompositions of sample paths, martingale problems, stochastic equations, Lamperti's transformations, independent and dependent immigration processes. Some of the results are simplified versions of those in the author's book "Measure-valued branching Markov processes" (Springer, 2011). We hope these simplified results will set out the main ideas in an easy way and lead the reader to a quick access of the subject.

  15. Wildlife and biological resources: Chapter 5 in A synthesis of aquatic science for management of Lakes Mead and Mohave

    Science.gov (United States)

    Chandra, Sudeep; Abella, Scott R.; Albrecht, Brandon A.; Barnes, Joseph G.; Engel, E. Cayenne; Goodbred, Steven L.; Holden, Paul B.; Kegerries, Ron B.; Jaeger, Jef R.; Orsak, Erik; Rosen, Michael R.; Sjöberg, Jon; Wong, Wai Hing

    2012-01-01

    The creation of Lakes Mead and Mohave drastically changed habitats originally found along their region of the historical Colorado River. While still continuing to provide habitat conditions that support a rich diversity of species within the water, along shorelines, and in adjacent drainage areas, the reservoirs contain organisms that are both native and non-native to the Colorado River drainage (fig. 5-1). The diversity of species within these lakes continues to change with time due to changing habitat conditions, the invasion of non-native species, and extirpations of native species. From the bottom of the food web to the top predators, all organisms within the ecosystem are interconnected in food webs or food-chain networks. As non-native invasive species continue to be introduced into the lakes, alterations to the food web, species competition, and species predation likely will continue to change the ecosystem and populations of native organisms. Following an overview of the food web, this chapter summarizes information on aquatic and aquatic-dependent wildlife at Lakes Mead and Mohave and their relationships within the food web from members of lower trophic levels to the highest: phytoplankton, invertebrates, including zooplankton, and macroinvertebrates; fishes; and birds. The following sections describe the biological diversity, limiting factors, and ecological functions of these groups in Lake Mead, and to a lesser extent, in Lake Mohave.

  16. Reproductive resource partitioning in two sympatric Goniothalamus species (Annonaceae) from Borneo: floral biology, pollinator trapping and plant breeding system

    Science.gov (United States)

    Lau, Jenny Y. Y.; Pang, Chun-Chiu; Ramsden, Lawrence; Saunders, Richard M. K.

    2016-01-01

    The floral phenology, pollination ecology and breeding systems of two sympatric early-divergent angiosperms, Goniothalamus tapisoides and G. suaveolens (Annonaceae) are compared. The flowers are protogynous and morphologically similar, with anthesis over 23–25 h. Both species are predominantly xenogamous and pollinated by small beetles: G. tapisoides mainly by Curculionidae and G. suaveolens mainly by Nitidulidae. Coevolution and reproductive resource partitioning, reducing interspecific pollen transfer, is achieved by temporal isolation, due to contrasting floral phenologies; and ethological isolation, due to contrasting floral scents that contain attractants specific to the two beetle families. Analysis of floral scents revealed three volatiles (3-methylbutyl acetate, ethyl hexanoate and 2-phenylethanol) that are known to be nitidulid attractants in the floral scent of G. suaveolens, but absent from that of G. tapisoides. An effective pollinator trapping mechanism is demonstrated for both species, representing the first such report for the family. Trapping is achieved by the compression of the outer petals against the apertures between the inner petals. This trapping mechanism is likely to be a key evolutionary innovation for Goniothalamus, increasing pollination efficiency by increasing pollen loading on beetles during the staminate phase, promoting effective interfloral pollinator movements, and increasing seed-set by enabling rapid turn-over of flowers. PMID:27767040

  17. Left bundle-branch block

    DEFF Research Database (Denmark)

    Risum, Niels; Strauss, David; Sogaard, Peter;

    2013-01-01

    The relationship between myocardial electrical activation by electrocardiogram (ECG) and mechanical contraction by echocardiography in left bundle-branch block (LBBB) has never been clearly demonstrated. New strict criteria for LBBB based on a fundamental understanding of physiology have recently...

  18. A new RNA branching activity: the GIR1 ribozyme

    DEFF Research Database (Denmark)

    Nielsen, Henrik; Johansen, Steinar D

    2006-01-01

    The formation of lariat intermediates during the first step of splicing of group II introns and spliceosomal introns is a well-studied fundamental reaction in molecular biology. Apart from this prominent example, there are surprisingly few occurrences of branched nucleotides or even 2...

  19. Radiation effects on branched polysilanes

    Energy Technology Data Exchange (ETDEWEB)

    Maeda, K.; Seki, S.; Tagawa, S. [Osaka Univ., Ibaraki (Japan). Inst. of Scientific and Industrial Research; Shibata, H.; Iwai, T. [Tokyo Univ. (Japan). Research Center for Nuclear Science and Technology

    2000-03-01

    We observed crosslinking and scission caused by gamma radiation in linear and branched polysilanes which have from 5% to 33% of the branching points. The crosslinking reactions become predominant for the irradiation with branching density increasing. The cleavage did not take place exclusively at the branching points and branching polysilanes are sensitive to radiation extraordinary as compared with linear polysilane from a careful study of the radiolysis products of a series of polysilanes. This is due to the increasing Si {center_dot} contributing to the crosslinking reaction and that they are not resonance-stabilized by double bonds as the reaction mechanism in the irradiated polysilanes. However, the gelation curve in linear PMPS irradiated by 2 MeV He{sup +} is almost consistent with that in branching PMPS, indicating that the size of chemical track is responsible for the gel fraction. The crosslinking G value for high molecular weight PMPS irradiated by 2 MeV He{sup +} was drastically decreased as compared with that for low molecular weight. It suggests that there are a large number of intramolecular crosslinking points for high molecular weight PMPS. (author)

  20. Resource accumulation and biological characteristics of Solanum nigrum L. in Qinghai Province%青海省龙葵生物学特性及资源储量

    Institute of Scientific and Technical Information of China (English)

    苏旭; 刘玉萍; 吴学明

    2012-01-01

    Solarium nigrum L. Is a kind of important medical plant in Qing-Tibet Plateau and the whole plant could be used as medicine. It abundantly contains several kinds of alkaloids including biological alkaline, solanine, solaso-nine, etc. They have pharmacological effects on antiinflammation, antitussive and expectorant, leavening concentration of blood sugar and adjusting excitability of the central nervous system and so on. Meanwhile, the fruit of Sola-rum nigrum L. Have abundant nutritious components consisting of fructose, minerals, manifold amino acids, etc. But the resource of wild plant decreases markedly because of excessively exploration and execrable natural environmental conditions in Qing-Tibet Plateau, which is detrimental to ecological environmental protection of Qing-Tibet Plateau and sustainable utilization and exploitation of medical plants. In this paper, the biological characteristics, populated botanical characteristics, community and quantity characteristics and resource accumulation of Solarium nigrum L. In Qinghai Province were investigated by the method of pointing field, the least sample and statistics. Furthermore , the resource accumulation of it was calculated.%龙葵是青藏高原一种重要的野生药用植物,全草入药,富含生物甙、龙葵碱、澳洲茄碱等多种生物碱,具有抗炎、镇咳祛痰、影响血糖浓度以及调节中枢神经系统兴奋性等药理作用.同时,龙葵果营养成分丰富,富含果糖、矿物质和多种氨基酸等.但由于青藏高原自然环境条件恶劣,加之近年来对野生植物资源的过度开采,使得该野生植物资源量呈显著下降趋势,这对于青藏高原的生态环境保护及药用植物的开发利用都是不利的.文章采用野外定点法、最小样方法和统计学方法分别对青海省龙葵的植物学特性、群落数量特征和资源量进行了研究,并计算出龙葵的资源储量.

  1. The capabilities and limitations of conductance-based compartmental neuron models with reduced branched or unbranched morphologies and active dendrites

    OpenAIRE

    Hendrickson, Eric B.; Edgerton, Jeremy R.; Jaeger, Dieter

    2010-01-01

    Conductance-based neuron models are frequently employed to study the dynamics of biological neural networks. For speed and ease of use, these models are often reduced in morphological complexity. Simplified dendritic branching structures may process inputs differently than full branching structures, however, and could thereby fail to reproduce important aspects of biological neural processing. It is not yet well understood which processing capabilities require detailed branching structures. T...

  2. A space-averaged model of branched structures

    CERN Document Server

    Lopez, Diego; Michelin, Sébastien

    2014-01-01

    Many biological systems and artificial structures are ramified, and present a high geometric complexity. In this work, we propose a space-averaged model of branched systems for conservation laws. From a one-dimensional description of the system, we show that the space-averaged problem is also one-dimensional, represented by characteristic curves, defined as streamlines of the space-averaged branch directions. The geometric complexity is then captured firstly by the characteristic curves, and secondly by an additional forcing term in the equations. This model is then applied to mass balance in a pipe network and momentum balance in a tree under wind loading.

  3. Anomalous scaling in an age-dependent branching model.

    Science.gov (United States)

    Keller-Schmidt, Stephanie; Tuğrul, Murat; Eguíluz, Víctor M; Hernández-García, Emilio; Klemm, Konstantin

    2015-02-01

    We introduce a one-parametric family of tree growth models, in which branching probabilities decrease with branch age τ as τ(-α). Depending on the exponent α, the scaling of tree depth with tree size n displays a transition between the logarithmic scaling of random trees and an algebraic growth. At the transition (α=1) tree depth grows as (logn)(2). This anomalous scaling is in good agreement with the trend observed in evolution of biological species, thus providing a theoretical support for age-dependent speciation and associating it to the occurrence of a critical point. PMID:25768548

  4. Anomalous scaling in an age-dependent branching model

    OpenAIRE

    Keller-Schmidt, Stephanie; Tugrul, Murat; Víctor M Eguíluz; Hernández-García, Emilio; Klemm, Konstantin

    2015-01-01

    © 2015 American Physical Society. We introduce a one-parametric family of tree growth models, in which branching probabilities decrease with branch age τ as τ-α. Depending on the exponent α, the scaling of tree depth with tree size n displays a transition between the logarithmic scaling of random trees and an algebraic growth. At the transition (α=1) tree depth grows as (logn)2. This anomalous scaling is in good agreement with the trend observed in evolution of biological species, thus provid...

  5. Anomalous scaling in an age-dependent branching model.

    Science.gov (United States)

    Keller-Schmidt, Stephanie; Tuğrul, Murat; Eguíluz, Víctor M; Hernández-García, Emilio; Klemm, Konstantin

    2015-02-01

    We introduce a one-parametric family of tree growth models, in which branching probabilities decrease with branch age τ as τ(-α). Depending on the exponent α, the scaling of tree depth with tree size n displays a transition between the logarithmic scaling of random trees and an algebraic growth. At the transition (α=1) tree depth grows as (logn)(2). This anomalous scaling is in good agreement with the trend observed in evolution of biological species, thus providing a theoretical support for age-dependent speciation and associating it to the occurrence of a critical point.

  6. Evaluation of the Modern State of Water Ecosystems and the Issues with Protecting Biological Resources During Development of the Kruzenshternskoye Gas Condensate Field

    Directory of Open Access Journals (Sweden)

    Vladimir Dmitrievich Bogdanov

    2015-09-01

    Full Text Available In the article, the results of the studies of the present state of freshwater ecosystems and their biotic components in the western part of the Yamal Peninsula are presented. Based on the evaluation of the structure of the communities of phytoplankton, zooplankton, benthos and whitefishes, the range of the problems related to the protection of biological resources at the development of the Kruzenshternskoye gas field is defined. Data on species composition and quantitative indicators of hydrobionts of different types of waterbodies and watercourses in the lower reaches of the Mordyyakha and Naduyyakha rivers basins are the basis for environmental monitoring of water objects at development and exploitation of the Kruzenshternskoye gas field. According to the monitoring program, evaluation of the fish fauna state and their food base on the territory of the Kruzenshternskoye gas condensate field (GCF, is present. The zones of rivers deltas are the most important areas of the salmonid and whitefishes valuable fish species feeding at the territory of Kruzenshternskoye GCF. In the cases where complete demolish of waterbodies and watercourses for construction of facilities for GCF does not occur, changes of quantitative and qualitative characteristics of communities of hydrobionts after cease of works are reversible. River ecosystems are restored within a more short period of time in comparison to lacustrine ones. On the basis of conducted comprehensive studies, the proposals for the protection of fisheries resources and monitoring of aquatic ecosystems are reported. Recommendations for reducing the anthropogenic impact on aquatic ecosystems in the development period are presented. The results of the investigation were used in the designing the environmental protection part of the Kruzenshternskoye deposit project. At present, the disturbances in the territory of Kruzenshternskoye deposit of gas does not impact the aquatic ecosystems

  7. Multiple pathways regulate shoot branching

    Directory of Open Access Journals (Sweden)

    Catherine eRameau

    2015-01-01

    Full Text Available Shoot branching patterns result from the spatio-temporal regulation of axillary bud outgrowth. Numerous endogenous, developmental and environmental factors are integrated at the bud and plant levels to determine numbers of growing shoots. Multiple pathways that converge to common integrators are most probably involved. We propose several pathways involving not only the classical hormones auxin, cytokinins and strigolactones, but also other signals with a strong influence on shoot branching such as gibberellins, sugars or molecular actors of plant phase transition. We also deal with recent findings about the molecular mechanisms and the pathway involved in the response to shade as an example of an environmental signal controlling branching. We propose the TCP transcription factor TB1/BRC1 and the polar auxin transport stream in the stem as possible integrators of these pathways. We finally discuss how modeling can help to represent this highly dynamic system by articulating knowledges and hypothesis and calculating the phenotype properties they imply.

  8. Warped branches of flux compactifications

    CERN Document Server

    Lim, Yen-Kheng

    2012-01-01

    We consider Freund-Rubin-type compactifications which are described by (p+q)-dimensional Einstein gravity with a positive cosmological constant and a q-form flux. Using perturbative expansions of Kinoshita's ansatz for warped dS_pxS^q and AdS_pxS^q spacetimes, we obtain analytical solutions describing the warped branches and their respective phase spaces. These equations are given by inhomogeneous Gegenbauer differential equations which can be solved by the Green's function method. The requirement that the Green's functions are regular provides constraints which determine the structure of the phase space of the warped branches. We apply the perturbation results to calculate the thermodynamic variables for the warped dS_pxS^q branch. In particular, the first law of thermodynamics can be reproduced using this method.

  9. Fluctuation induces evolutionary branching in a mathematical model of ecosystems.

    Directory of Open Access Journals (Sweden)

    Masashi Tachikawa

    Full Text Available Ecological systems are always subjected to various environmental fluctuations. They evolve under these fluctuations and the resulting systems are robust against them. The diversity in ecological systems is also acquired through the evolution. How do the fluctuations affect the evolutionary processes? Do the fluctuations have direct impact on the species diversity in ecological systems? In the present paper, we investigate the relation between the environmental fluctuation and the evolution of species diversity with a mathematical model of evolutionary ecology. In the model, individual organisms compete for a single restricted resource and the temporal fluctuation in the resource supply is introduced as the environmental fluctuation. The evolutionary process is represented by the mutational change of genotypes which determines their resource utilization strategies. We found that when the environmental state is switched form static to fluctuating conditions, the initial closely related population distributed around the genotype adapted for the static environment is destabilized and divided into two groups in the genotype space; i.e., the evolutionary branching is induced by the environmental fluctuation. The consequent multiple species structures is evolutionary stable at the presence of the fluctuation. We perform the evolutionary invasion analysis for the phenomena and illustrate the mechanisms of the branchings. The results indicate a novel process of increasing the species diversity via evolutionary branching, and the analysis reveals the mechanisms of the branching process as the response to the environmental fluctuation. The robustness of the evolutionary process is also discussed.

  10. Bioinformatics resource manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools

    Directory of Open Access Journals (Sweden)

    Tilton Susan C

    2012-11-01

    Full Text Available Abstract Background MicroRNAs (miRNAs are noncoding RNAs that direct post-transcriptional regulation of protein coding genes. Recent studies have shown miRNAs are important for controlling many biological processes, including nervous system development, and are highly conserved across species. Given their importance, computational tools are necessary for analysis, interpretation and integration of high-throughput (HTP miRNA data in an increasing number of model species. The Bioinformatics Resource Manager (BRM v2.3 is a software environment for data management, mining, integration and functional annotation of HTP biological data. In this study, we report recent updates to BRM for miRNA data analysis and cross-species comparisons across datasets. Results BRM v2.3 has the capability to query predicted miRNA targets from multiple databases, retrieve potential regulatory miRNAs for known genes, integrate experimentally derived miRNA and mRNA datasets, perform ortholog mapping across species, and retrieve annotation and cross-reference identifiers for an expanded number of species. Here we use BRM to show that developmental exposure of zebrafish to 30 uM nicotine from 6–48 hours post fertilization (hpf results in behavioral hyperactivity in larval zebrafish and alteration of putative miRNA gene targets in whole embryos at developmental stages that encompass early neurogenesis. We show typical workflows for using BRM to integrate experimental zebrafish miRNA and mRNA microarray datasets with example retrievals for zebrafish, including pathway annotation and mapping to human ortholog. Functional analysis of differentially regulated (p Conclusions BRM provides the ability to mine complex data for identification of candidate miRNAs or pathways that drive phenotypic outcome and, therefore, is a useful hypothesis generation tool for systems biology. The miRNA workflow in BRM allows for efficient processing of multiple miRNA and mRNA datasets in a single

  11. Branching of keratin intermediate filaments.

    Science.gov (United States)

    Nafeey, Soufi; Martin, Ines; Felder, Tatiana; Walther, Paul; Felder, Edward

    2016-06-01

    Keratin intermediate filaments (IFs) are crucial to maintain mechanical stability in epithelial cells. Since little is known about the network architecture that provides this stiffness and especially about branching properties of filaments, we addressed this question with different electron microscopic (EM) methods. Using EM tomography of high pressure frozen keratinocytes, we investigated the course of several filaments in a branching of a filament bundle. Moreover we found several putative bifurcations in individual filaments. To verify our observation we also visualized the keratin network in detergent extracted keratinocytes with scanning EM. Here bifurcations of individual filaments could unambiguously be identified additionally to bundle branchings. Interestingly, identical filament bifurcations were also found in purified keratin 8/18 filaments expressed in Escherichia coli which were reassembled in vitro. This excludes that an accessory protein contributes to the branch formation. Measurements of the filament cross sectional areas showed various ratios between the three bifurcation arms. This demonstrates that intermediate filament furcation is very different from actin furcation where an entire new filament is attached to an existing filament. Instead, the architecture of intermediate filament bifurcations is less predetermined and hence consistent with the general concept of IF formation. PMID:27039023

  12. NCI: DCTD: Biometric Research Branch

    Science.gov (United States)

    The Biometric Research Branch (BRB) is the statistical and biomathematical component of the Division of Cancer Treatment, Diagnosis and Centers (DCTDC). Its members provide statistical leadership for the national and international research programs of the division in developmental therapeutics, developmental diagnostics, diagnostic imaging and clinical trials.

  13. Strategy of Irrigation Branch in Russia

    Science.gov (United States)

    Zeyliger, A.; Ermolaeva, O.

    2012-04-01

    At this moment, at the starting time of the program on restoration of a large irrigation in Russia till 2020, the scientific and technical community of irrigation branch does not have clear vision on how to promote a development of irrigated agriculture and without repeating of mistakes having a place in the past. In many respects absence of a vision is connected to serious backlog of a scientific and technical and informational and technological level of development of domestic irrigation branch from advanced one. Namely such level of development is necessary for the resolving of new problems in new conditions of managing, and also for adequate answers to new challenges from climate and degradation of ground & water resources, as well as a rigorous requirement from an environment. In such important situation for irrigation branch when it is necessary quickly generate a scientific and technical politics for the current decade for maintenance of translation of irrigated agriculture in the Russian Federation on a new highly effective level of development, in our opinion, it is required to carry out open discussion of needs and requirements as well as a research for a adequate solutions. From political point of view a framework organized in FP6 DESIRE 037046 project is an example of good practice that can serve as methodical approach how to organize and develop such processes. From technical point of view a technology of operational management of irrigation at large scale presents a prospective alternative to the current type of management based on planning. From point of view ICT operational management demands creation of a new platform for the professional environment of activity. This platform should allow to perceive processes in real time, at their partial predictability on signals of a straight line and a feedback, within the framework of variability of decision making scenarious, at high resolution and the big ex-awning of sensor controls and the gauges

  14. The wetland biological resources evaluation and exploitation and utilization in Dongting lake region%洞庭湖区湿地生物资源评价及开发利用

    Institute of Scientific and Technical Information of China (English)

    庄大昌; 董明辉

    2001-01-01

    洞庭湖湿地是我国最大的淡水湖泊湿地之一,生物资源十分丰富。其中植物1428种,鸟类216种,鱼类119种,哺乳类22种,两栖爬行类27种。本文分析了 洞庭湖湿地生物资源的特征,并进行了定性评价,指出了洞 庭湖湿地生物资源利用现状及存在的主要问题,并就今后本区湿地生物资源的保护和利用提出了 一些构想。%The Dong-ting lake wetland is one of the largest lacu strine wetland in China. The biological resource is very plentiful. It includes 1428 species of plants resour ces, 216 species of birds resources, 119 species of fish resources, 27 species of amphibians and retile, 2 2 species of mammals and a great many of other wild living things. . Based on this, the biological re source character is analyzed and evaluated. In the end, the existing problems on the protection and developing of wetland biological resources are analyzed. A little imagination is made for the future r esource protection and utilization.

  15. 贝母药物资源的植物化学和生物学研究%Phytochemical and biological research of Fritillaria medicinal resources

    Institute of Scientific and Technical Information of China (English)

    郝大程; 顾晓洁; 肖培根; 彭勇

    2013-01-01

    贝母属药用植物含有多种药用化合物,在传统中医药中已应用上千年.近年对贝母药物资源的深入研究导致在多种贝母中发现更多的甾体生物碱、皂苷、萜类、糖苷和许多其它化合物,由此关于贝母的化学分类,分子系统发育和药理研究也日益增多.本文基于作者的贝母药用亲缘研究,评述近年贝母属植物化学、化学分类、分子生物和系统发育研究的进展,及其与贝母药效的关联.通过检索文献总结了贝母研究涉及的多种技术,用基于细胞核和质体DNA标记的系统发育分析推断了川贝,伊贝等复合群内部的相互关系和其与其它中国贝母物种的关系,并明确了中国贝母与国外贝母之间的关系.指出化学分类与分子系统发育结果的不一致并讨论了原因.深入研究更多的贝母物种对于贝母药物资源的可持续利用和寻找新的治疗用化合物十分重要.系统生物学和组学技术将对今后贝母药用化合物研究的深入起到关键作用.%The genus Fritillaria is a botanical source for various pharmaceutically active components,which have been commonly used in traditional Chinese medicine for thousands of years.Increasing interest in Fritillaria medicinal resources has led to additional discoveries of steroidal alkaloids,saponins,terpenoids,glycosides and many other compounds in various Fritillaria species,and to investigations on their chemotaxonomy,molecular phylogeny and pharmacology.In continuation of studies on Fritillaria pharmacophylogeny,the phytochemistry,chemotaxonomy,molecular biology and phylogeny of Fritillaria and their relevance to drug efficacy is reviewed.Literature searching is used to characterize the global scientific effort in the flexible technologies being applied.The interrelationship within Chinese Bei Mu species and between Chinese species,and species distributed outside of China,is clarified by the molecular phylogenetic inferences

  16. 农村幼儿园本土生物类课程资源的开发与利用%Development and Utilization of Local Biological Curriculum Resources of Rural Kindergarten

    Institute of Scientific and Technical Information of China (English)

    王立志

    2013-01-01

    Kindergarten curriculum of biological resources is an important component of kindergarten curriculum resources .It decided to kindergarten science teaching content ,which can realize one of the im‐portant factors .The level of the development and utilization of kindergarten curriculum of biological re‐sources not only directly affects the kindergarten curriculum resources construction quality ,but also relat‐ed to the kindergarten teaching reform practice successfully .This article from the countryside kindergarten curriculum of biological resources development concept ,analyses the characteristics of its development , and proposed in this foundation the rural kindergarten biological course resources development in an effec‐tive way .%  幼儿园生物类课程资源是幼儿园课程资源的重要组成部分,是决定幼儿园科学领域教学内容能否实现的重要因素之一,其开发利用的水平不仅直接影响着幼儿园课程资源建设质量,也关系到幼儿园教学改革实践的顺利进行。从农村幼儿园生物类课程资源开发的理念入手,分析其开发的特征,可以找到农村幼儿园生物类课程资源开发的有效途径。

  17. BDC 500 branch driver controller

    CERN Document Server

    Dijksman, A

    1981-01-01

    This processor has been designed for very fast data acquisition and date pre-processing. The dataway and branch highway speeds have been optimized for approximately 1.5 mu sec. The internal processor cycle is approximately 0.8 mu sec. The standard version contains the following functions (slots): crate controller type A1; branch highway driver including terminator; serial I/O port (TTY, VDU); 24 bit ALU and 24 bit program counter; 16 bit memory address counter and 4 word stack; 4k bit memory for program and/or data; battery backup for the memory; CNAFD and crate LAM display; request/grant logic for time- sharing operation of several BDCs. The free slots can be equipped with e.g. extra RAM, computer interfaces, hardware multiplier/dividers, etc. (0 refs).

  18. Solid State Photovoltaic Research Branch

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-01

    This report summarizes the progress of the Solid State Photovoltaic Research Branch of the Solar Energy Research Institute (SERI) from October 1, 1988, through September 30,l 1989. Six technical sections of the report cover these main areas of SERIs in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Laser Raman and Luminescence Spectroscopy. Sections have been indexed separately for inclusion on the data base.

  19. Creep of welded branched pipes

    OpenAIRE

    Rayner, Glen

    2004-01-01

    Creep failure of welds in high-temperature power plant steam piping systems is known to be a potential cause of plant failure. Creep behaviour of plain pipes with circumferential welds and cross-weld specimens have received fairly extensive attention. However, research into the creep behaviour of welded thick-walled branched steam pipes has received less attention. Consequently, this thesis addresses improving the understanding of the creep behaviour for this type of geometry. Numerical and a...

  20. Interactions between Axillary Branches of Arabidopsis

    Institute of Scientific and Technical Information of China (English)

    Veronica Ongaro; Katherine Bainbridge; Lisa Williamson; Ottoline Leyser

    2008-01-01

    Studies of apical dominance have benefited greatly from two-branch assays in pea and bean,in which the shoot system is trimmed back to leave only two active cotyledonary axillary branches.In these two-branch shoots,a large body of evidence shows that one actively growing branch is able to inhibit the growth of the other,prompting studies on the nature of the inhibitory signals,which are still poorly understood.Here,we describe the establishment of two-branch assays in Arabidopsis,using consecutive branches on the bolting stem.As with the classical studies in pea and bean,these consecutive branches are able to inhibit one another's growth.Not only can the upper branch inhibit the lower branch,but also the lower branch can inhibit the upper branch,illustrating the bi-directional action of the inhibitory signals.Using mutants,we show that the inhibition is partially dependent on the MAX pathway and that while the inhibition is clearly transmitted across the stem from the active to the inhibited branch,the vascular connectivity of the two branches is weak,and the MAX pathway is capable of acting unilaterally in the stem.

  1. Branching processes and neutral evolution

    CERN Document Server

    Taïb, Ziad

    1992-01-01

    The Galton-Watson branching process has its roots in the problem of extinction of family names which was given a precise formulation by F. Galton as problem 4001 in the Educational Times (17, 1873). In 1875, an attempt to solve this problem was made by H. W. Watson but as it turned out, his conclusion was incorrect. Half a century later, R. A. Fisher made use of the Galton-Watson process to determine the extinction probability of the progeny of a mutant gene. However, it was J. B. S. Haldane who finally gave the first sketch of the correct conclusion. J. B. S. Haldane also predicted that mathematical genetics might some day develop into a "respectable branch of applied mathematics" (quoted in M. Kimura & T. Ohta, Theoretical Aspects of Population Genetics. Princeton, 1971). Since the time of Fisher and Haldane, the two fields of branching processes and mathematical genetics have attained a high degree of sophistication but in different directions. This monograph is a first attempt to apply the current sta...

  2. Developing Engineering-oriented Educational Workshops Within a Student Branch

    OpenAIRE

    Verveckken, Jan; Geth, Frederik; Hunyadi, Borbála; Beerten, Jef; Leemput, Niels; Roy, Juan Van; Tielens, Pieter; De Smedt, Valentijn; Iacovella, Sandro; Koolen, Ninah; De Clercq, Hans; Driesen, Johan; Gielen, Georges; Puers, Bob; Vandewalle, Joos

    2013-01-01

    The development of two educational workshops, one on energy efficiency and one on human-machine interfaces, is detailed and discussed. Attraction to engineering is not created as much as lost at early ages through current education methods. Through positive, hands-on experiences with engineering in K-12 education, this trend can be turned. IEEE student branches have as part of their mission the education and creation of quality educational resources for the public. After searching in vain for...

  3. Mechanical properties of branched actin filaments

    CERN Document Server

    Razbin, Mohammadhosein; Benetatos, Panayotis; Zippelius, Annette

    2015-01-01

    Cells moving on a two dimensional substrate generate motion by polymerizing actin filament networks inside a flat membrane protrusion. New filaments are generated by branching off existing ones, giving rise to branched network structures. We investigate the force-extension relation of branched filaments, grafted on an elastic structure at one end and pushing with the free ends against the leading edge cell membrane. Single filaments are modeled as worm-like chains, whose thermal bending fluctuations are restricted by the leading edge cell membrane, resulting in an effective force. Branching can increase the stiffness considerably; however the effect depends on branch point position and filament orientation, being most pronounced for intermediate tilt angles and intermediate branch point positions. We describe filament networks without cross-linkers to focus on the effect of branching. We use randomly positioned branch points, as generated in the process of treadmilling, and orientation distributions as measur...

  4. The Effects of a Branch Campus

    Science.gov (United States)

    Lien, Donald; Wang, Yaqin

    2012-01-01

    We examine the effects of a branch campus on the social welfare of the host country and the foreign university. Overall, we find that a branch campus increases both the domestic social welfare (measured by the aggregate student utility) and the tuition revenue of the foreign university. The effect of a branch campus on the brain drain is…

  5. Stochastic Transition between Turbulent Branch and Thermodynamic Branch of an Inhomogeneous Plasma

    OpenAIRE

    Kawasaki, Mitsuhiro; Itoh, Sanae-I.; Yagi, Masatoshi; Itoh, Kimitaka

    2002-01-01

    Transition phenomena between thermodynamic branch and turbulent branch in submarginal turbulent plasma are analyzed with statistical theory. Time-development of turbulent fluctuation is obtained by numerical simulations of Langevin equation which contains submarginal characteristics. Probability density functions and transition rates between two states are analyzed. Transition from turbulent branch to thermodynamic branch occurs in almost entire region between subcritical bifurcation point an...

  6. 新疆克拉玛依资源开发与生物多样性问题和对策分析%Resource Development and Biological Diversity and Countermeasures in Karamay

    Institute of Scientific and Technical Information of China (English)

    陈婷婷

    2011-01-01

    克拉玛依具有丰富的石油和天然气资源,还具有丰富的动植物资源,包括野生动物、野生植物以及230种中草药。对各种资源的开发利用在位克拉玛依带来巨大的经济效益的同时,也给克拉玛依的生物多样性问题带来了影响。本文结合克拉玛依资源和生物多样性现状,总结和分析了资源开发与生物多样性之间的问题,并提出了相关的对策和建议。%Karamay has rich oil and gas resources, but also has rich flora and fauna, including wild animals, wild plants and 230 kinds of herbs. The development and utilization of various resources to bring tremendous economic benefits Karamay reign, but also to the Karamay had an impact on biological diversity. In this paper, resources and biological diversity conservation in Karamay, summary and analysis of resources between development and biodiversity issues and put forward some countermeasures and suggestions.

  7. PICO: An Object-Oriented Framework for Branch and Bound

    Energy Technology Data Exchange (ETDEWEB)

    ECKSTEIN,JONATHAN; HART,WILLIAM E.; PHILLIPS,CYNTHIA A.

    2000-12-01

    This report describes the design of PICO, a C++ framework for implementing general parallel branch-and-bound algorithms. The PICO framework provides a mechanism for the efficient implementation of a wide range of branch-and-bound methods on an equally wide range of parallel computing platforms. We first discuss the basic architecture of PICO, including the application class hierarchy and the package's serial and parallel layers. We next describe the design of the serial layer, and its central notion of manipulating subproblem states. Then, we discuss the design of the parallel layer, which includes flexible processor clustering and communication rates, various load balancing mechanisms, and a non-preemptive task scheduler running on each processor. We describe the application of the package to a branch-and-bound method for mixed integer programming, along with computational results on the ASCI Red massively parallel computer. Finally we describe the application of the branch-and-bound mixed-integer programming code to a resource constrained project scheduling problem for Pantex.

  8. Evaluation and Choice of Various Branch Predictors for Low-Power Embedded Processor

    Institute of Scientific and Technical Information of China (English)

    FAN DongRui (范东睿); YANG HongBo (杨洪波); GAO GuangRong (高光荣); ZHAO RongCai (赵荣彩)

    2003-01-01

    Power is an important design constraint in embedded computing systems. To meet the power constraint, microarchitecture and hardware designed to achieve high performance need to be revisited, from both performance and power angles. This paper studies one of them:branch predictor. As well known, branch prediction is critical to exploit instruction level parallelism effectively, but may incur additional power consumption due to the hardware resource dedicated for branch prediction and the extra power consumed on mispredicted branches. This paper explores the design space of branch prediction mechanisms and tries to find the most beneficial one to realize low-power embedded processor. The sample processor studied is Godson-like processor, which is a dual-issue, out-of-order processor with deep pipeline, supporting MIPS instruction set.

  9. When Two Worlds Collide: Ownership of Genetic Resources unde rthe Convention on Biological Diversity and the Agreement on Trade-Related Aspects of Intellectual Property Rights

    Directory of Open Access Journals (Sweden)

    Greg K. Venbrux

    2006-04-01

    Full Text Available The rapid growth of the biotechnology industry over the past two decades led many countries to recognize the vast economic potential of their genetic resources and indigenous knowledge. 1  Pharmaceutical companies and plant breeders increasingly rely upon these resources to engineer plantderived drugs, disease-resistant crops, and biotechnical production processes.2 With increasing demand for new biotechnological products, the global community is struggling to strike a balance between the interests of host countries, who seek remuneration for supplying genetic resources and traditional knowledge, and biotechnological inventors, who are pressing for free access, open markets, and stronger intellectual property rights protection.

  10. Branching diffusions in random environment

    CERN Document Server

    Böinghoff, Christian

    2011-01-01

    We consider the diffusion approximation of branching processes in random environment (BPREs). This diffusion approximation is similar to and mathematically more tractable than BPREs. We obtain the exact asymptotic behavior of the survival probability. As in the case of BPREs, there is a phase transition in the subcritical regime due to different survival opportunities. In addition, we characterize the process conditioned to never go extinct and establish a backbone construction. In the strongly subcritical regime, mean offspring numbers are increased but still subcritical in the process conditioned to never go extinct. Here survival is solely due to an immortal individual, whose offspring are the ancestors of additional families. In the weakly subcritical regime, the mean offspring number is supercritical in the process conditioned to never go extinct. Thus this process survives with positive probability even if there was no immortal individual.

  11. Recursive Branching Simulated Annealing Algorithm

    Science.gov (United States)

    Bolcar, Matthew; Smith, J. Scott; Aronstein, David

    2012-01-01

    This innovation is a variation of a simulated-annealing optimization algorithm that uses a recursive-branching structure to parallelize the search of a parameter space for the globally optimal solution to an objective. The algorithm has been demonstrated to be more effective at searching a parameter space than traditional simulated-annealing methods for a particular problem of interest, and it can readily be applied to a wide variety of optimization problems, including those with a parameter space having both discrete-value parameters (combinatorial) and continuous-variable parameters. It can take the place of a conventional simulated- annealing, Monte-Carlo, or random- walk algorithm. In a conventional simulated-annealing (SA) algorithm, a starting configuration is randomly selected within the parameter space. The algorithm randomly selects another configuration from the parameter space and evaluates the objective function for that configuration. If the objective function value is better than the previous value, the new configuration is adopted as the new point of interest in the parameter space. If the objective function value is worse than the previous value, the new configuration may be adopted, with a probability determined by a temperature parameter, used in analogy to annealing in metals. As the optimization continues, the region of the parameter space from which new configurations can be selected shrinks, and in conjunction with lowering the annealing temperature (and thus lowering the probability for adopting configurations in parameter space with worse objective functions), the algorithm can converge on the globally optimal configuration. The Recursive Branching Simulated Annealing (RBSA) algorithm shares some features with the SA algorithm, notably including the basic principles that a starting configuration is randomly selected from within the parameter space, the algorithm tests other configurations with the goal of finding the globally optimal

  12. Oil pollution and the significant biological resources of Puget Sound : final report field survey from 16 July 1974 to 01 September 1976 (NODC Accession 7601556)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Biological and chemical data were collected using sediment sampler and other instruments in the PUGET Sound, which is in the Northwest coastal waters of Washington....

  13. Artificial Intelligence Research Branch future plans

    Science.gov (United States)

    Stewart, Helen (Editor)

    1992-01-01

    This report contains information on the activities of the Artificial Intelligence Research Branch (FIA) at NASA Ames Research Center (ARC) in 1992, as well as planned work in 1993. These activities span a range from basic scientific research through engineering development to fielded NASA applications, particularly those applications that are enabled by basic research carried out in FIA. Work is conducted in-house and through collaborative partners in academia and industry. All of our work has research themes with a dual commitment to technical excellence and applicability to NASA short, medium, and long-term problems. FIA acts as the Agency's lead organization for research aspects of artificial intelligence, working closely with a second research laboratory at the Jet Propulsion Laboratory (JPL) and AI applications groups throughout all NASA centers. This report is organized along three major research themes: (1) Planning and Scheduling: deciding on a sequence of actions to achieve a set of complex goals and determining when to execute those actions and how to allocate resources to carry them out; (2) Machine Learning: techniques for forming theories about natural and man-made phenomena; and for improving the problem-solving performance of computational systems over time; and (3) Research on the acquisition, representation, and utilization of knowledge in support of diagnosis design of engineered systems and analysis of actual systems.

  14. Synthetic biology: insights into biological computation.

    Science.gov (United States)

    Manzoni, Romilde; Urrios, Arturo; Velazquez-Garcia, Silvia; de Nadal, Eulàlia; Posas, Francesc

    2016-04-18

    Organisms have evolved a broad array of complex signaling mechanisms that allow them to survive in a wide range of environmental conditions. They are able to sense external inputs and produce an output response by computing the information. Synthetic biology attempts to rationally engineer biological systems in order to perform desired functions. Our increasing understanding of biological systems guides this rational design, while the huge background in electronics for building circuits defines the methodology. In this context, biocomputation is the branch of synthetic biology aimed at implementing artificial computational devices using engineered biological motifs as building blocks. Biocomputational devices are defined as biological systems that are able to integrate inputs and return outputs following pre-determined rules. Over the last decade the number of available synthetic engineered devices has increased exponentially; simple and complex circuits have been built in bacteria, yeast and mammalian cells. These devices can manage and store information, take decisions based on past and present inputs, and even convert a transient signal into a sustained response. The field is experiencing a fast growth and every day it is easier to implement more complex biological functions. This is mainly due to advances in in vitro DNA synthesis, new genome editing tools, novel molecular cloning techniques, continuously growing part libraries as well as other technological advances. This allows that digital computation can now be engineered and implemented in biological systems. Simple logic gates can be implemented and connected to perform novel desired functions or to better understand and redesign biological processes. Synthetic biological digital circuits could lead to new therapeutic approaches, as well as new and efficient ways to produce complex molecules such as antibiotics, bioplastics or biofuels. Biological computation not only provides possible biomedical and

  15. Synthetic biology: insights into biological computation.

    Science.gov (United States)

    Manzoni, Romilde; Urrios, Arturo; Velazquez-Garcia, Silvia; de Nadal, Eulàlia; Posas, Francesc

    2016-04-18

    Organisms have evolved a broad array of complex signaling mechanisms that allow them to survive in a wide range of environmental conditions. They are able to sense external inputs and produce an output response by computing the information. Synthetic biology attempts to rationally engineer biological systems in order to perform desired functions. Our increasing understanding of biological systems guides this rational design, while the huge background in electronics for building circuits defines the methodology. In this context, biocomputation is the branch of synthetic biology aimed at implementing artificial computational devices using engineered biological motifs as building blocks. Biocomputational devices are defined as biological systems that are able to integrate inputs and return outputs following pre-determined rules. Over the last decade the number of available synthetic engineered devices has increased exponentially; simple and complex circuits have been built in bacteria, yeast and mammalian cells. These devices can manage and store information, take decisions based on past and present inputs, and even convert a transient signal into a sustained response. The field is experiencing a fast growth and every day it is easier to implement more complex biological functions. This is mainly due to advances in in vitro DNA synthesis, new genome editing tools, novel molecular cloning techniques, continuously growing part libraries as well as other technological advances. This allows that digital computation can now be engineered and implemented in biological systems. Simple logic gates can be implemented and connected to perform novel desired functions or to better understand and redesign biological processes. Synthetic biological digital circuits could lead to new therapeutic approaches, as well as new and efficient ways to produce complex molecules such as antibiotics, bioplastics or biofuels. Biological computation not only provides possible biomedical and

  16. Similarities Between Biological and Social Networks in Their Structural Organization

    Science.gov (United States)

    Kahng, Byungnam; Lee, Deokjae; Kim, Pureun

    A branching tree is a tree that is generated through a multiplicative branching process starting from a root. A critical branching tree is a branching tree in which the mean branching number of each node is 1, so that the number of offspring neither decays to zero nor flourishes as the branching process goes on. Moreover, a scale-free branching tree is a branching tree in which the number of offspring is heterogeneous, and its distribution follows a power law. Here we examine three structures, two from biology (a phylogenetic tree and the skeletons of a yeast protein interaction network) and one from social science (a coauthorship network), and find that all these structures are scale-free critical branching trees. This suggests that evolutionary processes in such systems take place in bursts and in a self-organized manner.

  17. Vegetation survey of PEN Branch wetlands

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    A survey was conducted of vegetation along Pen Branch Creek at Savannah River Site (SRS) in support of K-Reactor restart. Plants were identified to species by overstory, understory, shrub, and groundcover strata. Abundance was also characterized and richness and diversity calculated. Based on woody species basal area, the Pen Branch delta was the most impacted, followed by the sections between the reactor and the delta. Species richness for shrub and groundcover strata were also lowest in the delta. No endangered plant species were found. Three upland pine areas were also sampled. In support of K Reactor restart, this report summarizes a study of the wetland vegetation along Pen Branch. Reactor effluent enters Indian Grove Branch and then flows into Pen Branch and the Pen Branch Delta.

  18. A tool for simulating parallel branch-and-bound methods

    Science.gov (United States)

    Golubeva, Yana; Orlov, Yury; Posypkin, Mikhail

    2016-01-01

    The Branch-and-Bound method is known as one of the most powerful but very resource consuming global optimization methods. Parallel and distributed computing can efficiently cope with this issue. The major difficulty in parallel B&B method is the need for dynamic load redistribution. Therefore design and study of load balancing algorithms is a separate and very important research topic. This paper presents a tool for simulating parallel Branchand-Bound method. The simulator allows one to run load balancing algorithms with various numbers of processors, sizes of the search tree, the characteristics of the supercomputer's interconnect thereby fostering deep study of load distribution strategies. The process of resolution of the optimization problem by B&B method is replaced by a stochastic branching process. Data exchanges are modeled using the concept of logical time. The user friendly graphical interface to the simulator provides efficient visualization and convenient performance analysis.

  19. A tool for simulating parallel branch-and-bound methods

    Directory of Open Access Journals (Sweden)

    Golubeva Yana

    2016-01-01

    Full Text Available The Branch-and-Bound method is known as one of the most powerful but very resource consuming global optimization methods. Parallel and distributed computing can efficiently cope with this issue. The major difficulty in parallel B&B method is the need for dynamic load redistribution. Therefore design and study of load balancing algorithms is a separate and very important research topic. This paper presents a tool for simulating parallel Branchand-Bound method. The simulator allows one to run load balancing algorithms with various numbers of processors, sizes of the search tree, the characteristics of the supercomputer’s interconnect thereby fostering deep study of load distribution strategies. The process of resolution of the optimization problem by B&B method is replaced by a stochastic branching process. Data exchanges are modeled using the concept of logical time. The user friendly graphical interface to the simulator provides efficient visualization and convenient performance analysis.

  20. 3D modelling of branching in plants

    OpenAIRE

    Evers, J.B.

    2011-01-01

    Shoot branching is a key determinant of overall aboveground plant form. During plant development, the number of branches formed strongly influences the amount of light absorbed by the plant, and thus the plant’s competitive strength in terms of light capture in relation to neighbouring plants. Branching is regulated by multiple internal factors which are modulated by different environmental signals. A key environmental signal in the context of a plant population is a low red / far-red intensi...

  1. Supercritical branching diffusions in random environment

    CERN Document Server

    Hutzenthaler, Martin

    2011-01-01

    Supercritical branching processes in constant environment conditioned on eventual extinction are known to be subcritical branching processes. The case of random environment is more subtle. A supercritical branching diffusion in random environment (BDRE) conditioned on eventual extinction of the population is not a BDRE. However the quenched law of the population size of a supercritical BDRE conditioned on eventual extinction is equal to the quenched law of the population size of a subcritical BDRE. As a consequence, supercritical BDREs have a phase transition which is similar to a well-known phase transition of subcritical branching processes in random environment.

  2. Current perspectives on shoot branching regulation

    Directory of Open Access Journals (Sweden)

    Cunquan YUAN,Lin XI,Yaping KOU,Yu ZHAO,Liangjun ZHAO

    2015-03-01

    Full Text Available Shoot branching is regulated by the complex interactions among hormones, development, and environmental factors. Recent studies into the regulatory mecha-nisms of shoot branching have focused on strigolactones, which is a new area of investigation in shoot branching regulation. Elucidation of the function of the D53 gene has allowed exploration of detailed mechanisms of action of strigolactones in regulating shoot branching. In addition, the recent discovery that sucrose is key for axillary bud release has challenged the established auxin theory, in which auxin is the principal agent in the control of apical dominance. These developments increase our understan-ding of branching control and indicate that regulation of shoot branching involves a complex network. Here, we first summarize advances in the systematic regulatory network of plant shoot branching based on current information. Then we describe recent developments in the synthesis and signal transduction of strigolactones. Based on these considerations, we further summarize the plant shoot branching regulatory network, including long distance systemic signals and local gene activity mediated by strigolactones following perception of external envi-ronmental signals, such as shading, in order to provide a comprehensive overview of plant shoot branching.

  3. Clinical and Translational Epidemiology Branch (CTEB)

    Science.gov (United States)

    The Clinical and Translational Epidemiology Branch focuses on factors that influence cancer progression, recurrence, survival, and other treatment outcomes, and factors associated with cancer development.

  4. Networks of companies and branches in Poland

    CERN Document Server

    Chmiel, A M; Sienkiewicz, J; Suchecki, K; Chmiel, Anna M.; Holyst, Janusz A.; Sienkiewicz, Julian; Suchecki, Krzysztof

    2006-01-01

    In this study we consider relations between companies in Poland taking into account common branches they belong to. It is clear that companies belonging to the same branch compete for similar customers, so the market induces correlations between them. On the other hand two branches can be related by companies acting in both of them. To remove weak, accidental links we shall use a concept of threshold filtering for weighted networks where a link weight corresponds to a number of existing connections (common companies or branches) between a pair of nodes.

  5. Fishery Biology Database (AGDBS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Basic biological data are the foundation on which all assessments of fisheries resources are built. These include parameters such as the size and age composition of...

  6. Rare Germplasm Resources of Biology of Agriculture in Yunnan Province and Its Peripheral Area%云南及周边地区稀有农业生物种质资源

    Institute of Scientific and Technical Information of China (English)

    郑殿升; 高爱农; 李立会; 刘旭

    2013-01-01

    “云南及周边地区生物资源调查”项目于2006-2011年,对云南省31个县、四川省8个县和西藏自治区2个县的农业生物资源进行了系统调查.系统调查的41个县的地形、地貌十分多样,气候类型很多,有“一山有四季,十里不同天”的说法.加之,这些县份都集居有少数民族,少数民族有各自的传统文化和生活习俗,从而赋予了农业生物资源丰富的民族文化内涵.正因为这里的多样性气候和各异的民族文化,造就了丰富的农业生物资源.通过调查获得了大量基础数据和信息,收集到5300多份农业生物种质资源,其中有一批稀有种质资源,这些稀有种质资源对相应农业生物的起源进化和系统分类研究,以及新品种选育都具有重要利用价值.%From 2006 to 2011 ,the project of "investigation of biological resources in Yunnan province and its peripheral area" has been carried out,which has conducted a systematic survey on agricultural biological resources of 31 counties in Yunnan province,8 counties in Sichuan province,and 2 counties in Tibet autonomous region. The terrains and landforms in the 41 counties investigated are plenty diverse,so does the climate,which is described as a proverb that is ' there are four seasons at the same mountains, and five miles in the different weathers'. In additions , these counties are the concentrative areas inhabited by minority peoples who possess their own traditional culture and life habitudes, which has endued the biological resources of agriculture with abundant connotations of nationality cultures. The different climates and diverse traditional cultures have resulted in abundant biological resources of agriculture. Many of basic data and information, and over 5300 accessions of biological germplasm resources of agriculture have been obtained. Some of them are rare germplasm resources, which has important value in appropriate research on origin, evolution, and

  7. Biological Databases

    Directory of Open Access Journals (Sweden)

    Kaviena Baskaran

    2013-12-01

    Full Text Available Biology has entered a new era in distributing information based on database and this collection of database become primary in publishing information. This data publishing is done through Internet Gopher where information resources easy and affordable offered by powerful research tools. The more important thing now is the development of high quality and professionally operated electronic data publishing sites. To enhance the service and appropriate editorial and policies for electronic data publishing has been established and editors of article shoulder the responsibility.

  8. Branch mode selection during early lung development.

    Directory of Open Access Journals (Sweden)

    Denis Menshykau

    Full Text Available Many organs of higher organisms, such as the vascular system, lung, kidney, pancreas, liver and glands, are heavily branched structures. The branching process during lung development has been studied in great detail and is remarkably stereotyped. The branched tree is generated by the sequential, non-random use of three geometrically simple modes of branching (domain branching, planar and orthogonal bifurcation. While many regulatory components and local interactions have been defined an integrated understanding of the regulatory network that controls the branching process is lacking. We have developed a deterministic, spatio-temporal differential-equation based model of the core signaling network that governs lung branching morphogenesis. The model focuses on the two key signaling factors that have been identified in experiments, fibroblast growth factor (FGF10 and sonic hedgehog (SHH as well as the SHH receptor patched (Ptc. We show that the reported biochemical interactions give rise to a Schnakenberg-type Turing patterning mechanisms that allows us to reproduce experimental observations in wildtype and mutant mice. The kinetic parameters as well as the domain shape are based on experimental data where available. The developed model is robust to small absolute and large relative changes in the parameter values. At the same time there is a strong regulatory potential in that the switching between branching modes can be achieved by targeted changes in the parameter values. We note that the sequence of different branching events may also be the result of different growth speeds: fast growth triggers lateral branching while slow growth favours bifurcations in our model. We conclude that the FGF10-SHH-Ptc1 module is sufficient to generate pattern that correspond to the observed branching modes.

  9. Branch mode selection during early lung development.

    Science.gov (United States)

    Menshykau, Denis; Kraemer, Conradin; Iber, Dagmar

    2012-01-01

    Many organs of higher organisms, such as the vascular system, lung, kidney, pancreas, liver and glands, are heavily branched structures. The branching process during lung development has been studied in great detail and is remarkably stereotyped. The branched tree is generated by the sequential, non-random use of three geometrically simple modes of branching (domain branching, planar and orthogonal bifurcation). While many regulatory components and local interactions have been defined an integrated understanding of the regulatory network that controls the branching process is lacking. We have developed a deterministic, spatio-temporal differential-equation based model of the core signaling network that governs lung branching morphogenesis. The model focuses on the two key signaling factors that have been identified in experiments, fibroblast growth factor (FGF10) and sonic hedgehog (SHH) as well as the SHH receptor patched (Ptc). We show that the reported biochemical interactions give rise to a Schnakenberg-type Turing patterning mechanisms that allows us to reproduce experimental observations in wildtype and mutant mice. The kinetic parameters as well as the domain shape are based on experimental data where available. The developed model is robust to small absolute and large relative changes in the parameter values. At the same time there is a strong regulatory potential in that the switching between branching modes can be achieved by targeted changes in the parameter values. We note that the sequence of different branching events may also be the result of different growth speeds: fast growth triggers lateral branching while slow growth favours bifurcations in our model. We conclude that the FGF10-SHH-Ptc1 module is sufficient to generate pattern that correspond to the observed branching modes. PMID:22359491

  10. ECONOMIC ISSUES OF BRANCH PRODUCTION

    Directory of Open Access Journals (Sweden)

    Shamrov K. N.

    2015-05-01

    Full Text Available The article deals with topical questions of economy industry production of rice grain. The need for improving the business efficiency of rice today is dictated by political and economic sanctions, the needs of our society in full substitution of this important product. State stimulation of rice development today is carried out through a complex of economic and administrative activities. The economic measures of the state include: price control on rice price and processing products, support of agricultural producers’ incomes, leasing involving the state, marketing of products, and infrastructure development of the grain market. The system of public administrative measures also includes standardization and certification of grain products, control quality of grain and products of its processing, the quarantine protection, licensing activities organizations, and mandatory statistical account of the rice market. These measures are intended to ensure equal conditions of competition between local and imported rice, to spur investment and expansion of domestic production, increase profitability of rice, allowing the rice enterprises to carry out expensive irrigation systems repairs and capital inputs in lot lend. The article suggests that rice branch industry remains competitive and with abolition of import customs barriers within frameworks WTO. It is necessary to invest more heavily in infrastructure with the aim of improving business efficiency of rice

  11. Defining biodiversity resources

    OpenAIRE

    Gadgil, Madhav

    2000-01-01

    The scope of the Biological Diversity Bill, tabled in the monsoon 2000 session of the Indian Parliament is excessively wide covering all biological resources. Instead it should focus on diversity related end-uses such as drugs, industrial enzymes, cosmetics, dyestuffs, plant growth regulators, emulsifiers, oleoresins and genes used for improving crops and livestock through breeding and genetic intervention. It should seek to regulate collection and movement of such biodiversity resources and ...

  12. 12 CFR 741.11 - Foreign branching.

    Science.gov (United States)

    2010-01-01

    ...) Contents of Business Plan. The written business plan must address the following: (1) Analysis of market... regarding the branch (shares, lending, capital, charge-offs, collections); (6) The field of membership or... for branch operations (balance sheet and income and expense projections) for the first and second...

  13. Branching out Has So Much to Offer

    Science.gov (United States)

    Murray, Joe

    2012-01-01

    In 1989 there were thirty ATM branches nationally. In January 2012 there were just twelve ATM branches with another three "proposed". How can that happen? How did it happen? Maybe the most pertinent question is: Why did it happen? There is no single answer to the last question, but perhaps it was something to do with the changes that were sweeping…

  14. Summary of activities of the Research Branch during 1981

    International Nuclear Information System (INIS)

    A general view of the work performed during 1981 by CNEA's Research Branch in basic and applied research is provided. The information includes the main activities and achievements in: 1) Physics Department: Tandar Project; Technical Assistance and Engineering; Experimental and Theoretical Nuclear Physics; Solid State Physics. 2) Reactor Chemistry Department: Chemical Control Division; Moderator and Coolant Physical-Chemistry Division; Radiation Chemistry Division. 3) Radiobiology Department: Radiation Pathology; Cellular Biology; Somatic Effects of the Ionizing Radiations; Genetics; Radiomicrobiology; Bioterium; Irradiation and Dosimetry Section, and, finally, in Biomathematics, Labelled Molecules and Radiochemistry. (M.E.L.)

  15. Chemical and Biological Kinetics

    Science.gov (United States)

    Emanuel', N. M.

    1981-10-01

    Examples of the application of the methods and ideas of chemical kinetics in various branches of chemistry and biology are considered and the results of studies on the kinetics and mechanisms of autoxidation and inhibited and catalysed oxidation of organic substances in the liquid phase are surveyed. Problems of the kinetics of the ageing of polymers and the principles of their stabilisation are discussed and certain trends in biological kinetics (kinetics of tumour growth, kinetic criteria of the effectiveness of chemotherapy, problems of gerontology, etc.) are considered. The bibliography includes 281 references.

  16. [Croatian Medical Association--Branch Zagreb].

    Science.gov (United States)

    Kaić, Zvonimir; Sain, Snjezana; Gulić, Mirjana; Mahovlić, Vjekoslav; Krznarić, Zeljko

    2014-01-01

    The available literature shows us that "Druztvo ljeciteljah u Zagrebus (the Society of Healers in Zagreb) was founded as far back as the year 1845 by a total of thirteen members. This data allows us to follow the role of doctors and health workers in Zagreb through their everyday profession, research, organizational and social work as well as management through a period of over one hundred to seventy years. The Branch Zagreb was active before the official establishment of subsidiaries of CMA which is evident from the minutes of the regular annual assembly of the Croatian Medical Association on 21 March 1948. Until the end of 1956, there was no clear division of labor, functions and competencies between the Branch and the Main Board. Their actions were instead consolidated and the Branch operated within and under the name of Croatian Medical Association. In that year the Branch became independent. The Branch Zagreb is the largest and one of the most active branches of the Croatian Medical Association. At the moment, the Branch brings together 3621 members, regular members--doctors of medicine (2497), doctors of dental medicine (384), retired physicians (710), and associate members (30 specialists with higher education who are not doctors). The Branch is especially accomplished in its activities in the area of professional development of its members and therefore organizes a series of scientific conferences in the framework of continuous education of physicians, allowing its members to acquire necessary points for the extension of their operating license. The choir "Zagrebacki lijecnici pjevaci" (Zagreb Physicians' Choir) of the Croatian Medical Music Society of the CMA and its activities are inseparable from the Branch Zagreb. The Branch is firmly linked to the parent body, the CMA, and thus has a visible impact on the strategy and the activities of the Association as a whole. Most professional societies of the CMA have their headquarters in Zagreb and this is

  17. Electrophoretic dynamics of self-assembling branched DNA structures

    Science.gov (United States)

    Heuer, Daniel Milton

    . By designing branch-creating probes, sequence detection was easily accomplished. For mutation detection, p53 fragments with single nucleotide mutations found in cancer patients were analyzed. 100% of all analyzed mutations were detected. This technique is rapid, straightforward, and can be performed with standard equipment found in most molecular biology laboratories. The results presented here are expected to have a far-reaching impact in many areas of separation science and genetic analysis.

  18. Branch architecture, light interception and crown development in saplings of a plagiotropically branching tropical tree, Polyalthia jenkinsii (Annonaceae).

    Science.gov (United States)

    Osada, Noriyuki; Takeda, Hiroshi

    2003-01-01

    To investigate crown development patterns, branch architecture, branch-level light interception, and leaf and branch dynamics were studied in saplings of a plagiotropically branching tree species, Polyalthia jenkinsii Hk. f. & Thoms. (Annonaceae) in a Malaysian rain forest. Lengths of branches and parts of the branches lacking leaves ('bare' branches) were smaller in upper branches than in lower branches within crowns, whereas lengths of 'leafy' parts and the number of leaves per branch were larger in intermediate than in upper and lower branches. Maximum diffuse light absorption (DLA) of individual leaves was not related to sapling height or branch position within crowns, whereas minimum DLA was lower in tall saplings. Accordingly, branch-level light interception was higher in intermediate than in upper and lower branches. The leaf production rate was higher and leaf loss rate was smaller in upper than in intermediate and lower branches. Moreover, the branch production rate of new first-order branches was larger in the upper crowns. Thus, leaf and branch dynamics do not correspond to branch-level light interception in the different canopy zones. As a result of architectural constraints, branches at different vertical positions experience predictable light microenvironments in plagiotropic species. Accordingly, this pattern of carbon allocation among branches might be particularly important for growth and crown development in plagiotropic species. PMID:12495920

  19. TUMOR SELECTIVE DRUG DELIVERY BY NEUROTENSIN BRANCHED PEPTIDES

    Directory of Open Access Journals (Sweden)

    L. Depau

    2012-05-01

    Full Text Available Detection of new tumor-selective targets, which allow either cancer cell tracing or therapy, is a crucial issue in cancer research. Membrane receptors for endogenous peptides such as Neurotensin are over-expressed in many human cancers and could therefore be used as tumor-specific antigen, while peptide ligands might act as targeting agents. The development of peptides as drug has always been limited by their short half-life, due to degradation by peptidases and proteases. Chemical modification, which can stabilize the molecules, may modify peptide affinity or specificity. More- over, coupling of peptides to effector units for imaging or therapy, may interfere with biological activity. We demonstrated that peptide sequences, when synthesized in an oligo-branched form, be- come resistant to proteolysis and thank to their multimericity are more efficient than correspon- ding monomers in binding cellular antigens1. Moreover, the branched core allow coupling of effector units without affecting peptide activity. Drug-armed tetra-branched neurotensin peptides (NT4 were synthesized with different conjugation methods, resulting either in uncleavable adducts or drug-releasing molecules2-4. Recently we de- veloped DOPC liposomes filled with the cytotoxic drug Doxorubicin (Doxo and functionalized with NT4. Armed DOPC liposomes showed a clear advantage with respect to nude liposomes in drug internalization and their cytotoxicity is fourfold increased with respect to the same nude lipo- somes. Conjugation to NT4 switches drug internalization to a peptide-receptor mediated mechanism, which greatly increases drug selectivity and also might allow by-passing drug cell resistance. In vitro and in vivo results indicated that branched NT peptides are valuable tools for tumor selective targeting.

  20. Measurement of Prominent eta Decay Branching Fractions

    CERN Document Server

    López, A; Méndez, H; Ramírez, J; Ge, J Y; Miller, D H; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Menaa, N; Mountain, R; Nisar, S; Randrianarivony, K; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Asner, D M; Edwards, K W; Naik, P; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Ernst, J; Ecklund, K M; Severini, H; Love, W; Savinov, V

    2007-01-01

    The decay psi(2S) --> eta J/psi is used to measure, for the first time, all prominent eta-meson branching fractions with the same experiment in the same dataset, thereby providing a consistent treatment of systematics across branching fractions. We present results for eta decays to gamma gamma, pi+pi-pi0, 3 pi0, pi+ pi- gamma, and e+ e- gamma, accounting for 99.9% of all eta decays. The precisions for several of the branching fractions and their ratios are improved. Two channels, pi+ pi- gamma and e+ e- gamma, show results that differ at the level of three standard deviations from those previously determined.

  1. Cellular and physical mechanisms of branching morphogenesis

    Science.gov (United States)

    Varner, Victor D.; Nelson, Celeste M.

    2014-01-01

    Branching morphogenesis is the developmental program that builds the ramified epithelial trees of various organs, including the airways of the lung, the collecting ducts of the kidney, and the ducts of the mammary and salivary glands. Even though the final geometries of epithelial trees are distinct, the molecular signaling pathways that control branching morphogenesis appear to be conserved across organs and species. However, despite this molecular homology, recent advances in cell lineage analysis and real-time imaging have uncovered surprising differences in the mechanisms that build these diverse tissues. Here, we review these studies and discuss the cellular and physical mechanisms that can contribute to branching morphogenesis. PMID:25005470

  2. Agents in branching space-times

    Institute of Scientific and Technical Information of China (English)

    Nuel; Belnap

    2003-01-01

    The aim of this essay Is to make some brief suggestions on the beginnings of a theory of agentsand agency In branching spacetlmes.foe thought Is to combine the ideas of agency as developed agalnst the relatively simple background of branching time with the richer notions of Indetermlnlsm asstructured In the theory of branching space-times.My plan Is to say a little about agency In branchingtime and a little about branchlg spacetlmes,and then ask how the two can be brought together.Atthe end there Is an ...

  3. The capabilities and limitations of conductance-based compartmental neuron models with reduced branched or unbranched morphologies and active dendrites.

    Science.gov (United States)

    Hendrickson, Eric B; Edgerton, Jeremy R; Jaeger, Dieter

    2011-04-01

    Conductance-based neuron models are frequently employed to study the dynamics of biological neural networks. For speed and ease of use, these models are often reduced in morphological complexity. Simplified dendritic branching structures may process inputs differently than full branching structures, however, and could thereby fail to reproduce important aspects of biological neural processing. It is not yet well understood which processing capabilities require detailed branching structures. Therefore, we analyzed the processing capabilities of full or partially branched reduced models. These models were created by collapsing the dendritic tree of a full morphological model of a globus pallidus (GP) neuron while preserving its total surface area and electrotonic length, as well as its passive and active parameters. Dendritic trees were either collapsed into single cables (unbranched models) or the full complement of branch points was preserved (branched models). Both reduction strategies allowed us to compare dynamics between all models using the same channel density settings. Full model responses to somatic inputs were generally preserved by both types of reduced model while dendritic input responses could be more closely preserved by branched than unbranched reduced models. However, features strongly influenced by local dendritic input resistance, such as active dendritic sodium spike generation and propagation, could not be accurately reproduced by any reduced model. Based on our analyses, we suggest that there are intrinsic differences in processing capabilities between unbranched and branched models. We also indicate suitable applications for different levels of reduction, including fast searches of full model parameter space. PMID:20623167

  4. Third annual Walker Branch watershed research symposium: Programs and abstracts

    International Nuclear Information System (INIS)

    The methods and concepts of watershed research, originally applied in an experimental or monitoring mode to relatively small catchments, are increasingly being used at larger scales and for specific applied problems. Research at Oak Ridge National Laboratory, the Tennessee Valley Authority, the US Forest Service, and other agencies and institutions participating in this symposium reflects research over a broad range of spatial scales. These research projects address the basic atmospheric, geophysical, biogeochemical, and biological processes that regulate the responses of forested ecosystems to natural environmental variation and anthropogenic stresses. Regional and global issues addressed by presentations include emissions of carbon dioxide, methane, and other hydrocarbons; deposition of sulfate, nitrate, and mercury; land-use changes; biological diversity; droughts; and water quality. The Department of Energy's local research site, Walker Branch Watershed, is a long-term ecosystem research project initiated on the Oak Ridge Reservation in 1967. Walker Branch provides a well-characterized site where many of these methods can be tested and applied.In addition, other large-scale experiments represented in this symposium include experiments on the effects of clearcutting and burning on forest structure and productivity associated with Coweeta Hydrologic Laboratory, and whole-tree ozone exposure chambers constructed by TVA and ORNL researchers

  5. Arkansas State University Beebe Branch Faculty Handbook.

    Science.gov (United States)

    Arkansas State Univ., Beebe.

    Arkansas State University Beebe Branch provides a liberal arts oriented program for traditional and nontraditional students. Its faculty handbook contains institutional goals, description of responsibilities of administrative officers and faculty committees, faculty employment policies, and administrative and instructional policies. The…

  6. Damping by branching: a bioinspiration from trees

    CERN Document Server

    Theckes, Benoit; Boutillon, Xavier

    2011-01-01

    Man-made slender structures are known to be sensitive to high levels of vibration, due to their flexibility, which often cause irreversible damage. In nature, trees repeatedly endure large amplitudes of motion, mostly caused by strong climatic events, yet with minor or no damage in most cases. A new damping mechanism inspired by the architecture of trees is here identified and characterized in the simplest tree-like structure, a Y-shape branched structure. Through analytical and numerical analyses of a simple two-degree-of-freedom model, branching is shown to be the key ingredient in this protective mechanism that we call damping-by-branching. It originates in the geometrical nonlinearities so that it is specifically efficient to damp out large amplitudes of motion. A more realistic model, using flexible beam approximation, shows that the mechanism is robust. Finally, two bioinspired architectures are analyzed, showing significant levels of damping achieved via branching with typically 30% of the energy being...

  7. Code 672 observational science branch computer networks

    Science.gov (United States)

    Hancock, D. W.; Shirk, H. G.

    1988-01-01

    In general, networking increases productivity due to the speed of transmission, easy access to remote computers, ability to share files, and increased availability of peripherals. Two different networks within the Observational Science Branch are described in detail.

  8. FY 1990 Applied Sciences Branch annual report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.M.; Dippo, P.C. [eds.

    1991-11-01

    The Applied Sciences Branch actively supports the advancement of DOE/SERI goals for the development and implementation of the solar photovoltaic technology. The primary focus of the laboratories is to provide state-of-the-art analytical capabilities for materials and device characterization and fabrication. The branch houses a comprehensive facility which is capable of providing information on the full range of photovoltaic components. A major objective of the branch is to aggressively pursue collaborative research with other government laboratories, universities, and industrial firms for the advancement of photovoltaic technologies. Members of the branch disseminate research findings to the technical community in publications and presentations. This report contains information on surface and interface analysis, materials characterization, development, electro-optical characterization module testing and performance, surface interactions and FTIR spectroscopy.

  9. Residence times of branching diffusion processes

    Science.gov (United States)

    Dumonteil, E.; Mazzolo, A.

    2016-07-01

    The residence time of a branching Brownian process is the amount of time that the mother particle and all its descendants spend inside a domain. Using the Feynman-Kac formalism, we derive the residence-time equation as well as the equations for its moments for a branching diffusion process with an arbitrary number of descendants. This general approach is illustrated with simple examples in free space and in confined geometries where explicit formulas for the moments are obtained within the long time limit. In particular, we study in detail the influence of the branching mechanism on those moments. The present approach can also be applied to investigate other additive functionals of branching Brownian process.

  10. Parton Branching in Color Mutation Model

    CERN Document Server

    Hwa, R C

    1999-01-01

    The soft production problem in hadronic collisions as described in the eikonal color mutation branching model is improved in the way that the initial parton distribution is treated. Furry branching of the partons is considered as a means of describing the nonperturbative process of parton reproduction in soft interaction. The values of all the moments, and $C_q$, for q=2,...,5, as well as their energy dependences can be correctly determined by the use of only two parameters.

  11. CAST Xi'an Branch Established

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ China Academy of Space Technology (CAST) Xi'an Branch was established on April 8,2008.The new branch consists of the headquarters of the former Xi'an Institute of Space Radio Technology (XISRT) of CAST and five former subsidiaries of the XISRT,i.e.the Institute of Space Electronic Technology,the Institute of Microwave Technology,the Institute of Space Antenna Technology,the Manufacturing Center for Space Electronics and Civilian High-tech Company.

  12. Comparative efficiency analysis of Portuguese bank branches

    OpenAIRE

    Portela, Maria; Thanassoulis, Emmanuel

    2006-01-01

    The advent of Internet banking and phone banking is changing the role of bank branches from a predominantly transaction- based one to a sales-oriented role. This paper reports on an assessment of the branches of a Portuguese bank in terms of their performance in their new roles in three different areas: Their efficiency in fostering the use of new transaction channels, their efficiency in increasing sales and their customer base, and their efficiency in generating profits. Service qu...

  13. Comparative performance analysis of portuguese bank branches

    OpenAIRE

    Portela, Maria; Thanassoulis, Emmanuel

    2003-01-01

    The advent of Internet banking and phone banking is changing the role of bank branches from a predominantly transaction-based one to a sales-oriented role. This paper reports on an assessment of the branches of a Portuguese bank in terms of their performance in their new roles in three different areas: Their effectiveness in fostering the use of new transaction channels such as the internet and the telephone, their effectiveness in increasing sales and their customer base, and the...

  14. AGB [asymptotic giant branch]: Star evolution

    International Nuclear Information System (INIS)

    Asymptotic giant branch stars are red supergiant stars of low-to-intermediate mass. This class of stars is of particular interest because many of these stars can have nuclear processed material brought up repeatedly from the deep interior to the surface where it can be observed. A review of recent theoretical and observational work on stars undergoing the asymptotic giant branch phase is presented. 41 refs

  15. Branch retinal artery occlusion in Susac's syndrome

    Directory of Open Access Journals (Sweden)

    Ricardo Evangelista Marrocos de Aragão

    2015-02-01

    Full Text Available Susac's syndrome is a rare disease attribuited to a microangiopathy involving the arterioles of the cochlea, retina and brain. Encefalopathy, hearing loss, and visual deficits are the hallmarks of the disease. Visual loss is due to multiple, recurrent branch arterial retinal occlusions. We report a case of a 20-year-old women with Susac syndrome presented with peripheral vestibular syndrome, hearing loss, ataxia, vertigo, and vision loss due occlusion of the retinal branch artery.

  16. All change at the CERN UBS branch

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    UBS branches across the country are being modernised, and the CERN branch is no exception. The Bulletin brings you a preview of the project, which will get under way in January 2013.   Mock-up of the renovated UBS branch. The changes at the UBS branch in CERN's Main Building will be no simple facelift. The entire bank will be renovated, transforming the present relatively confined premises into an open and attractive area. "The renovation of the UBS branches is part of a wider campaign designed to further enhance our customer relations," explains Ezio Mangia, the head of the CERN branch.  The UBS bank currently occupies three sets of premises in CERN's Main Building (two on the ground floor and one in the basement). "By the end of the work, which is scheduled to be completed by the middle of next year, CERN customers will benefit from a new area with open-plan counters and "hole-in-the-wall" machines accessible to...

  17. Functional morphology, biomechanics and biomimetic potential of stem-branch connections in Dracaena reflexa and Freycinetia insignis.

    Science.gov (United States)

    Masselter, Tom; Eckert, Sandra; Speck, Thomas

    2011-01-01

    Branching in plants is one of the most important assets for developing large arborescent growth forms with complex crowns. While the form and development of branching in gymnosperms and dicotyledonous trees is widely understood, very little is known about branching patterns and the structure of branch-stem-junctions in arborescent monocotyledons. For a better and quantitative understanding of the functional morphology of branch-stem-junctions in arborescent monocotyledons, we investigated the two species Dracaena reflexa and Freycinetia insignis. While D. reflexa is able to develop large arborescent forms with conspicuous crowns by anomalous secondary growth, F. insignis remains relatively small and is only capable of primary growth. Biomechanical investigations were performed by applying vertical loads up to rupture to lateral branches of both species. This allows the analysis of the fracture mechanics and the determination of the maximal force, stress and strain at rupture as well as the fracture toughness. Functional morphology was correlated with the mechanical behaviour of these plants and compared to data of other dicotyledonous trees. The high energy absorption found in the rupture process of lateral branches of D. reflexa and F. insignis makes them promising biological concept generators with a high potential for biomimetic implementation, i.e., for the development of branched fibre-reinforced technical composites. A wide range of constructional elements with branched (sub-)structures can be optimised by using solutions inspired by plant ramifications, e.g., in automotive and aerospace engineering, architecture, sports equipment and prosthetic manufacturing. PMID:21977429

  18. Functional morphology, biomechanics and biomimetic potential of stem-branch connections in Dracaena reflexa and Freycinetia insignis.

    Science.gov (United States)

    Masselter, Tom; Eckert, Sandra; Speck, Thomas

    2011-01-01

    Branching in plants is one of the most important assets for developing large arborescent growth forms with complex crowns. While the form and development of branching in gymnosperms and dicotyledonous trees is widely understood, very little is known about branching patterns and the structure of branch-stem-junctions in arborescent monocotyledons. For a better and quantitative understanding of the functional morphology of branch-stem-junctions in arborescent monocotyledons, we investigated the two species Dracaena reflexa and Freycinetia insignis. While D. reflexa is able to develop large arborescent forms with conspicuous crowns by anomalous secondary growth, F. insignis remains relatively small and is only capable of primary growth. Biomechanical investigations were performed by applying vertical loads up to rupture to lateral branches of both species. This allows the analysis of the fracture mechanics and the determination of the maximal force, stress and strain at rupture as well as the fracture toughness. Functional morphology was correlated with the mechanical behaviour of these plants and compared to data of other dicotyledonous trees. The high energy absorption found in the rupture process of lateral branches of D. reflexa and F. insignis makes them promising biological concept generators with a high potential for biomimetic implementation, i.e., for the development of branched fibre-reinforced technical composites. A wide range of constructional elements with branched (sub-)structures can be optimised by using solutions inspired by plant ramifications, e.g., in automotive and aerospace engineering, architecture, sports equipment and prosthetic manufacturing.

  19. Biological Threats

    Science.gov (United States)

    ... Workplace Plans School Emergency Plans Main Content Biological Threats Biological agents are organisms or toxins that can ... for Disease Control and Prevention . Before a Biological Threat Unlike an explosion, a biological attack may or ...

  20. Challenging (Strategic) Human Resource management Theory

    NARCIS (Netherlands)

    J. Paauwe (Jaap); J.P.P.E.F. Boselie (Paul)

    2002-01-01

    textabstractTo fully understand the relationship between human resource management and performance in different contexts, we are in need of a synthesis between resource-based theory and new institutionalism. We argue that differences in institutional settings (between for example countries or branch

  1. Synergy of multi-scale toughening and protective mechanisms at hierarchical branch-stem interfaces

    Science.gov (United States)

    Müller, Ulrich; Gindl-Altmutter, Wolfgang; Konnerth, Johannes; Maier, Günther A.; Keckes, Jozef

    2015-09-01

    Biological materials possess a variety of artful interfaces whose size and properties are adapted to their hierarchical levels and functional requirements. Bone, nacre, and wood exhibit an impressive fracture resistance based mainly on small crystallite size, interface organic adhesives and hierarchical microstructure. Currently, little is known about mechanical concepts in macroscopic biological interfaces like the branch-stem junction with estimated 1014 instances on earth and sizes up to few meters. Here we demonstrate that the crack growth in the upper region of the branch-stem interface of conifer trees proceeds along a narrow predefined region of transversally loaded tracheids, denoted as sacrificial tissue, which fail upon critical bending moments on the branch. The specific arrangement of the tracheids allows disconnecting the overloaded branch from the stem in a controlled way by maintaining the stem integrity. The interface microstructure based on the sharply adjusted cell orientation and cell helical angle secures a zig-zag crack propagation path, mechanical interlock closing after the bending moment is removed, crack gap bridging and self-repairing by resin deposition. The multi-scale synergetic concepts allows for a controllable crack growth between stiff stem and flexible branch, as well as mechanical tree integrity, intact physiological functions and recovery after the cracking.

  2. [Odd- and branched-chain fatty acids in milk fat--characteristic and health properties].

    Science.gov (United States)

    Adamska, Agata; Rutkowska, Jarosława

    2014-01-01

    This review analyzes the current state of knowledge on odd- and branched-chain fatty acids present in milk fat. Special attention is devoted to the characteristic, synthesis in ruminants, factors affecting their content in milk fat and pro-health properties of these compounds. The group of odd- and branched-chain fatty acids includes mainly saturated fatty acids with one or more methyl branches in the iso or anteiso position. These fatty acids are largely derived from ruminal bacteria and they have been transferred to ruminant tissue (milk and meat). For that reason they have been used as biomarkers of rumen fermentation. Odd- and branched-chain fatty acids are exogenous products for humans, and therefore have specific properties. The results of research from recent decades show that odd- and branched-chain fatty acids have anti-cancer activity. Branched-chain fatty acids may reduce the incidence of necrotizing enterocolitis. Additionally, these compounds have a beneficial effect on proper tissue function and on functioning and development of the infant gut, whereas odd-chain fatty acids are considered as biomarkers of milk fat intake by humans. So far, not all the mechanisms of activity of these compounds are known thoroughly. They should be more carefully studied for application of their biological effects in prevention and treatment. PMID:25228507

  3. Airway branching morphogenesis in three dimensional culture

    Directory of Open Access Journals (Sweden)

    Gudjonsson Thorarinn

    2010-11-01

    Full Text Available Abstract Background Lungs develop from the fetal digestive tract where epithelium invades the vascular rich stroma in a process called branching morphogenesis. In organogenesis, endothelial cells have been shown to be important for morphogenesis and the maintenance of organ structure. The aim of this study was to recapitulate human lung morphogenesis in vitro by establishing a three dimensional (3D co-culture model where lung epithelial cells were cultured in endothelial-rich stroma. Methods We used a human bronchial epithelial cell line (VA10 recently developed in our laboratory. This cell line cell line maintains a predominant basal cell phenotype, expressing p63 and other basal markers such as cytokeratin-5 and -14. Here, we cultured VA10 with human umbilical vein endothelial cells (HUVECs, to mimic the close interaction between these cell types during lung development. Morphogenesis and differentiation was monitored by phase contrast microscopy, immunostainings and confocal imaging. Results We found that in co-culture with endothelial cells, the VA10 cells generated bronchioalveolar like structures, suggesting that lung epithelial branching is facilitated by the presence of endothelial cells. The VA10 derived epithelial structures display various complex patterns of branching and show partial alveolar type-II differentiation with pro-Surfactant-C expression. The epithelial origin of the branching VA10 colonies was confirmed by immunostaining. These bronchioalveolar-like structures were polarized with respect to integrin expression at the cell-matrix interface. The endothelial-induced branching was mediated by soluble factors. Furthermore, fibroblast growth factor receptor-2 (FGFR-2 and sprouty-2 were expressed at the growing tips of the branching structures and the branching was inhibited by the FGFR-small molecule inhibitor SU5402. Discussion In this study we show that a human lung epithelial cell line can be induced by endothelial cells to

  4. Measurement of tau lepton branching fractions

    International Nuclear Information System (INIS)

    We present τ- lepton branching fraction measurements based on data from the TPC/Two-Gamma detector at PEP. Using a sample ofτ- → ντK-π+π- events, we examine the resonance structure of the K-π+π- system and obtain the first measurements of branching fractions for τ- → ντK1-(1270) and τ- → ντK1-(1400). We also describe a complete set of branching fraction measurements in which all the decays of the τ- lepton are separated into classes defined by the identities of the charged particles and an estimate of the number of neutrals. This is the first such global measurement with decay classes defined by the four possible charged particle species, e, μ, π, and K

  5. Heterogeneity of coronary arterial branching geometry

    Science.gov (United States)

    Wan, Shu-Yen; Reyes, Denise A.; Higgins, William E.; Ritman, Erik L.

    2000-04-01

    Past measurements of arterial branching geometry have indicated that the branching geometry is somewhat consistent with an optimal trade-off between the work needed to build and maintain the arterial tree and the work needed to operate the tree as a transport system. The branching geometry is also consistent with the mechanism that acutely adjusts the lumen diameter by way of maintaining a constant shear stress by dilating (or constricting) the arteries via the nitric oxide mechanism. However, those observations also indicate that there is considerable variation about the predicted optimization, both within any one individual and between individuals. Possible causes for this variation include: (1) measurement noise -- both due to the imprecision of the method but also the preparation of the specimen for applying the measurement technique, (2) the fact that the measurement task presents a major logistic problem, which increases as the vessel size decreases (but the number of branches correspondingly doubles at each branching) and results in progressive under-sampling as the vessel size decreases, (3) because of the logistic task involved the number of arterial trees analyzed is also greatly limited, and (4) there may indeed be actual heterogeneity in the geometry which is due to slight variation in implementation of the 'rules' used to construct a vascular tree. Indeed, it is this latter possibility that is of considerable physiological interest as it could result in the observed heterogeneity of organ perfusion and also provide some insight into the relative importance of 'initial ' conditions (i.e., how the vascular tree initially develops during embryogenesis) and the adaptive mechanisms operative in the maturing individual. The use of micro-CT imaging to provide 3D images of the intact vascular tree within the intact organ overcomes or minimizes the logistic problems listed above. It is the purpose of this study to examine whether variability in the branching

  6. Grand challenges in space synthetic biology

    OpenAIRE

    Menezes, Amor A.; Montague, Michael G.; Cumbers, John; Hogan, John A.; Arkin, Adam P.

    2015-01-01

    Space synthetic biology is a branch of biotechnology dedicated to engineering biological systems for space exploration, industry and science. There is significant public and private interest in designing robust and reliable organisms that can assist on long-duration astronaut missions. Recent work has also demonstrated that such synthetic biology is a feasible payload minimization and life support approach as well. This article identifies the challenges and opportunities that lie ahead in the...

  7. The branching channel network in the Yangtze Estuary

    NARCIS (Netherlands)

    Wang, Z.B.; Ding, P.X.

    2012-01-01

    The channels in the Yangtze Estuary have an ordered-branching structure: The estuary is first divided by the Chongming Island into the North Branch and the South Branch. Then the South Branch is divided into the North Channel and South Channel by the Islands Changxing and Hengsha. The South Channel

  8. General collision branching processes with two parameters

    Institute of Scientific and Technical Information of China (English)

    CHEN AnYue; LI JunPing

    2009-01-01

    A new class of branching models, the general collision branching processes with two parameters, is considered in this paper. For such models, it is necessary to evaluate the absorbing probabilities and mean extinction times for both absorbing states. Regularity and uniqueness criteria are firstly established. Explicit expressions are then obtained for the extinction probability vector, the mean extinction times and the conditional mean extinction times. The explosion behavior of these models is investigated and an explicit expression for mean explosion time is established. The mean global holding time is also obtained. It is revealed that these properties are substantially different between the super-explosive and sub-explosive cases.

  9. Logic, planning agency and branching time

    Directory of Open Access Journals (Sweden)

    Ricardo Souza Silvestre

    2010-12-01

    Full Text Available The purpose of this paper is to give a formal account of a kind of agency so far neglected in the field of philosophical modal logic of action: planning agency. In doing this we follow the standard approach of modal logics of agency exemplified by the works of Belnap, Chellas and Pörn. Since we believe there is a close relation between planning, time and indeterminism, we use the theory of branching time as a conceptual framework for investigating the basic features of planning agency. Besides introducing a branching-time semantics, we also provide a calculus sound and complete with respect to this semantics.

  10. Implications of an inverse branching aftershock sequence model.

    Science.gov (United States)

    Turcotte, D L; Abaimov, S G; Dobson, I; Rundle, J B

    2009-01-01

    The branching aftershock sequence (BASS) model is a self-similar statistical model for earthquake aftershock sequences. A prescribed parent earthquake generates a first generation of daughter aftershocks. The magnitudes and times of occurrence of the daughters are obtained from statistical distributions. The first generation daughter aftershocks then become parent earthquakes that generate second generation aftershocks. The process is then extended to higher generations. The key parameter in the BASS model is the magnitude difference Deltam* between the parent earthquake and the largest expected daughter earthquake. In the application of the BASS model to aftershocks Deltam* is positive, the largest expected daughter event is smaller than the parent, and the sequence of events (aftershocks) usually dies out, but an exponential growth in the number of events with time is also possible. In this paper we explore this behavior of the BASS model as Deltam* varies, including when Deltam* is negative and the largest expected daughter event is larger than the parent. The applications of this self-similar branching process to biology and other fields are discussed.

  11. Indexes system of technological condition assessment of economic branches

    Science.gov (United States)

    Chuvashova, M. N.; Avramchikova, N. T.; Antamoshkin, A. N.

    2015-10-01

    The increased level of innovative production process, connected with the current trends, points out the necessity of economic diversification of the whole national economy as well as regional economies in order to increase competitiveness and stable development. Russian regional economies are characterized with local directive of development and innovative processes have evident local vector. Intensive development of Siberian regional economies, which depends on oil and mining industries, considerably falls behind the world indicators according to the GRP output per head. To improve the quality of economic space the authors have suggested a new scientific approach, which allows qualitative assessment inside the economic space of resource-based regions, based on principles of high technological modes development inside economic branches taking into account density, regular enterprise distribution and connectivity of commercial organizations as well as secures innovative development of regional economy and its competitiveness. In this context it is necessary to develop a modern system of indexes, characterizing the structure of economic branches in accordance with present technological modes and at the same time the dynamics of appropriate structural shifts in regional economies of this type.

  12. Branch and Bound Experiments in Convex Nonlinear Integer Programming

    OpenAIRE

    Omprakash K. Gupta; Ravindran, A

    1985-01-01

    The branch and bound principle has long been established as an effective computational tool for solving mixed integer linear programming problems. This paper investigates the computational feasibility of branch and bound methods in solving convex nonlinear integer programming problems. The efficiency of a branch and bound method often depends on the rules used for selecting the branching variables and branching nodes. Among others, the concepts of pseudo-costs and estimations are implemented ...

  13. Effect of left bundle branch block on TIMI frame count

    OpenAIRE

    Hatice Tolunay; Ahmet Kasapkara; İsa Öner Yüksel; Nurcan Başar; Ayşe Saatcı Yaşar; Mehmet Bilge

    2010-01-01

    Aim: Left bundle branch block is an independent risk factorfor cardiac mortality. In this study we aimed to evaluatecoronary blood flow with TIMI frame count in patients with left bundle branch block and angiographically proven normal coronary arteries.Materials and methods: We retrospectively studied 17 patients with left bundle branch block and as a control group 16 patients without left bundle branch block. All patientshad angiographically proven normal coronary arteries.Left bundle branch...

  14. Challenging (Strategic) Human Resource management Theory

    OpenAIRE

    Paauwe, Jaap; Boselie, Paul

    2002-01-01

    textabstractTo fully understand the relationship between human resource management and performance in different contexts, we are in need of a synthesis between resource-based theory and new institutionalism. We argue that differences in institutional settings (between for example countries or branches of industry) affect the shaping of HRM. In this paper we develop a conceptual model (human resource based theory of the firm) that will be illustrated by means of empirical evidence on macro, me...

  15. The unique branching patterns of Deinococcus glycogen branching enzymes are determined by their N-terminal domains.

    NARCIS (Netherlands)

    Palomo, M.; Kralj, S.; van der Maarel, M. J. E. C.; Dijkhuizen, L.

    2009-01-01

    Glycogen branching enzymes (GBE) or 1,4-alpha-glucan branching enzymes (EC 2.4.1.18) introduce alpha-1,6 branching points in alpha-glucans, e.g., glycogen. To identify structural features in GBEs that determine their branching pattern specificity, the Deinococcus geothermalis and Deinococcus radiodu

  16. Resources to Riches?

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Africa's natural resources can be a cornerstone of development for some countries on the struggling continent Africa is a vast territory with abundant mineral and biological resources, and this is where great hope lies for a better future. Its valuable metallic reserves, which include gold, cobalt, platinum, chromium, manganese, titanium and vanadium, and mineral reserves, such as diamond, bauxite and phosphate, top the world. Its verified oil and natural gas deposits

  17. The Genome Atlas Resource

    OpenAIRE

    Azam Qureshi, Matloob; Rotenberg, Eva; Stærfeldt, Hans Henrik; Hansson, Lena; Ussery, David

    2010-01-01

    Abstract. The Genome Atlas is a resource for addressing the challenges of synchronising prokaryotic genomic sequence data from multiple public repositories. This resource can integrate bioinformatic analyses in various data format and quality. Existing open source tools have been used together with scripts and algorithms developed in a variety of programming languages at the Centre for Biological Sequence Analysis in order to create a three-tier software application for genome analysis. The r...

  18. Branching exponential flights: travelled lengths and collision statistics

    International Nuclear Information System (INIS)

    The evolution of several physical and biological systems, ranging from neutron transport in multiplying media to epidemics or population dynamics, can be described in terms of branching exponential flights, a stochastic process which couples a Galton–Watson birth–death mechanism with random spatial displacements. Within this context, one is often called to assess the length ℓV that the process travels in a given region V of the phase space, or the number of visits nV to this same region. In this paper, we address this issue by resorting to the Feynman–Kac formalism, which allows characterizing the full distribution of ℓV and nV and in particular deriving explicit moment formulas. Some other significant physical observables associated to ℓV and nV, such as the survival probability, are discussed as well, and results are illustrated by revisiting the classical example of the rod model in nuclear reactor physics. (paper)

  19. On the red giant branch mass loss in 47 Tucanae: Constraints from the horizontal branch morphology

    CERN Document Server

    Salaris, Maurizio; Pietrinferni, Adriano

    2016-01-01

    We obtain stringent constraints on the actual efficiency of mass loss for red giant branch stars in the Galactic globular cluster 47 Tuc, by comparing synthetic modeling based on stellar evolution tracks with the observed distribution of stars along the horizontal branch in the colour-magnitude-diagram. We confirm that the observed, wedge-shaped distribution of the horizontal branch can be reproduced only by accounting for a range of initial He abundances --in agreement with inferences from the analysis of the main sequence-- and a red giant branch mass loss with a small dispersion. We have carefully investigated several possible sources of uncertainty that could affect the results of the horizontal branch modeling, stemming from uncertainties in both stellar model computations and the cluster properties such as heavy element abundances, reddening and age. We determine a firm lower limit of ~0.17$Mo for the mass lost by red giant branch stars, corresponding to horizontal branch stellar masses between ~0.65Mo ...

  20. Medial branch neurotomy in low back pain

    International Nuclear Information System (INIS)

    This study aimed to assess the effectiveness of pulsed radiofrequency medial branch dorsal ramus neurotomy in patients with facet joint syndrome. From January 2008 to April 2010, 92 patients with facet joint syndrome diagnosed by strict inclusion criteria and controlled diagnostic blocks undergone medial branch neurotomy. We did not exclude patients with failed back surgery syndrome (FBSS). Electrodes (20G) with 5-mm active tip were placed under fluoroscopy guide parallel to medial branch. Patients were followed up by physical examination and by Visual Analog Scale and Oswestry Disability Index at 1, 6, and 12 months. In all cases, pain improvement was statistically significant and so quality of life. Three non-FBSS patients had to undergo a second neurotomy because of non-satisfactory pain decrease. Complications were reported in no case. Medial branch radiofrequency neurotomy has confirmed its well-established effectiveness in pain and quality of life improvement as long as strict inclusion criteria be fulfilled and nerve ablation be accomplished by parallel electrode positioning. This statement can be extended also to FBSS patients. (orig.)

  1. Branching Processes with Immigration and Related Topics

    Institute of Scientific and Technical Information of China (English)

    LI Zeng-hu

    2006-01-01

    This is a survey on the recent progresses in the study of branching processes with immigration,generalized Ornstein-Uhlenbeck processes,and affine Markov processes.We mainly focus on the applications of skew convolution semigroups and the connections in those processes.

  2. Medial branch neurotomy in low back pain

    Energy Technology Data Exchange (ETDEWEB)

    Masala, Salvatore; Mammucari, Matteo; Simonetti, Giovanni [Interventional Radiology and Radiotherapy University ' ' Tor Vergata' ' , Department of Diagnostic and Molecular Imaging, Rome (Italy); Nano, Giovanni [Interventional Radiology and Radiotherapy University ' ' Tor Vergata' ' , Department of Diagnostic and Molecular Imaging, Rome (Italy); University ' ' Tor Vergata' ' , Department of Radiology, Rome (Italy); Marcia, Stefano [S. Giovanni di Dio Hospital, Department of Diagnostic and Molecular Imaging, Cagliari (Italy)

    2012-07-15

    This study aimed to assess the effectiveness of pulsed radiofrequency medial branch dorsal ramus neurotomy in patients with facet joint syndrome. From January 2008 to April 2010, 92 patients with facet joint syndrome diagnosed by strict inclusion criteria and controlled diagnostic blocks undergone medial branch neurotomy. We did not exclude patients with failed back surgery syndrome (FBSS). Electrodes (20G) with 5-mm active tip were placed under fluoroscopy guide parallel to medial branch. Patients were followed up by physical examination and by Visual Analog Scale and Oswestry Disability Index at 1, 6, and 12 months. In all cases, pain improvement was statistically significant and so quality of life. Three non-FBSS patients had to undergo a second neurotomy because of non-satisfactory pain decrease. Complications were reported in no case. Medial branch radiofrequency neurotomy has confirmed its well-established effectiveness in pain and quality of life improvement as long as strict inclusion criteria be fulfilled and nerve ablation be accomplished by parallel electrode positioning. This statement can be extended also to FBSS patients. (orig.)

  3. Infrared studies of asymptotic giant branch stars

    International Nuclear Information System (INIS)

    In this thesis studies are presented of asymptotic giant branch stars, which are thought to be an important link in the evolution of the galaxy. The studies were performed on the basis of data collected by the IRAS, the infrared astronomical satelite. 233 refs.; 33 figs.; 16 tabs

  4. 76 FR 60757 - Executive Branch Qualified Trusts

    Science.gov (United States)

    2011-09-30

    ... portfolio must meet the diversification requirements of Sec. 2634.406(b)(2) of this subpart. (2) In the case... of the trust's portfolio would be materially enhanced. Additionally, as with the blind trust, the... qualified trusts provisions for the executive branch in subparts D and E of 5 CFR part 2634 (see 57 FR...

  5. Branch II : Neutrino Oscillations at Low Energies

    Energy Technology Data Exchange (ETDEWEB)

    Cabrera, A., E-mail: anatael@in2p3.fr [CNRS/IN2P3. Laboratoire d' Astro-Particule et Cosmologie. 10 rue Alice Domont et Leonie Duquet. Paris. 75205. Cedex 13 (France); Volpe, C., E-mail: volpe@ipno.in2p3.fr [Institut de Physique Nucleaire Orsay and University of Paris XI,CNRS/IN2P3, F-91406 Orsay cedex (France)

    2011-08-15

    We summarize here briefly the experimental and theoretical results presented at the NOW2010 workshop during the parallel session Branch II 'Oscillations at low energies'. The topics have covered open problems and recent advances in solar neutrinos, reactor and geo-neutrinos, as well as neutrinos from core-collapse supernovae.

  6. The AFCRL Lunar amd Planetary Research Branch

    Science.gov (United States)

    Price, Stephan D.

    2011-07-01

    The Lunar and Planetary research program led by Dr John (Jack) Salisbury in the 1960s at the United States Air Force Cambridge Research Laboratories (AFCRL) investigated the surface characteristics of Solar System bodies. The Branch was one of the first groups to measure the infrared spectra of likely surface materials in the laboratory under appropriate vacuum and temperature conditions. The spectral atlases created from the results were then compared to photometric and spectral measurements obtained from ground- and balloon-based telescopes to infer the mineral compositions and physical conditions of the regoliths of the Moon, Mars and asteroids. Starting from scratch, the Branch initially sponsored observations of other groups while its in-house facilities were being constructed. The earliest contracted efforts include the spatially-resolved mapping of the Moon in the first half of the 1960s by Richard W. Shorthill and John W. Saari of the Boeing Scientific Research Laboratories in Seattle. This effort ultimately produced isophotal and isothermal contour maps of the Moon during a lunation and time-resolved thermal images of the eclipsed Moon. The Branch also sponsored probe rocket-based experiments flown by Riccardo Giacconi and his group at American Science and Engineering Inc. that produced the first observations of X-ray stars in 1962 and later the first interferometric measurement of the ozone and C02 emission in the upper atmosphere. The Branch also made early use of balloon-based measurements. This was a singular set of experiments, as these observations are among the very few mid-infrared astronomical measurements obtained from a balloon platform. Notable results of the AFCRL balloon flights were the mid-infrared spectra of the spatially-resolved Moon obtained with the University of Denver mid-infrared spectrometer on the Branch's balloon-borne 61-cm telescope during a 1968 flight. These observations remain among the best available. Salisbury also funded

  7. Cryptococcus neoformans capsular polysaccharides form branched and complex filamentous networks viewed by high-resolution microscopy.

    Science.gov (United States)

    Araújo, Glauber R de S; Fontes, Giselle N; Leão, Daniela; Rocha, Gustavo Miranda; Pontes, Bruno; Sant'Anna, Celso; de Souza, Wanderley; Frases, Susana

    2016-01-01

    Cryptococcus neoformans is a fungal pathogen that causes life-threatening infections in immunocompromised individuals. Its main virulence factor is an extracellular polysaccharide capsule whose structure, assembly and dynamics remain poorly understood. In this study, we apply improved protocols for sample preparation and recently-developed scanning microscopy techniques to visualize the ultrastructure of the C. neoformans capsule at high-resolution (up to 1 nm) and improved structural preservation. Although most capsule structures in nature consist of linear polymers, we show here that the C. neoformans capsule is a 'microgel-like' structure composed of branched polysaccharides. Moreover, we imaged the capsule-to-cell wall link, which is formed by thin fibers that branch out of thicker capsule filaments, and have one end firmly embedded in the cell wall structure. Together, our findings provide compelling ultrastructural evidence for a branched and complex capsule conformation, which may have important implications for the biological activity of the capsule as a virulence factor.

  8. The Branching Bifurcation of Adaptive Dynamics

    Science.gov (United States)

    Della Rossa, Fabio; Dercole, Fabio; Landi, Pietro

    2015-06-01

    We unfold the bifurcation involving the loss of evolutionary stability of an equilibrium of the canonical equation of Adaptive Dynamics (AD). The equation deterministically describes the expected long-term evolution of inheritable traits — phenotypes or strategies — of coevolving populations, in the limit of rare and small mutations. In the vicinity of a stable equilibrium of the AD canonical equation, a mutant type can invade and coexist with the present — resident — types, whereas the fittest always win far from equilibrium. After coexistence, residents and mutants effectively diversify, according to the enlarged canonical equation, only if natural selection favors outer rather than intermediate traits — the equilibrium being evolutionarily unstable, rather than stable. Though the conditions for evolutionary branching — the joint effect of resident-mutant coexistence and evolutionary instability — have been known for long, the unfolding of the bifurcation has remained a missing tile of AD, the reason being related to the nonsmoothness of the mutant invasion fitness after branching. In this paper, we develop a methodology that allows the approximation of the invasion fitness after branching in terms of the expansion of the (smooth) fitness before branching. We then derive a canonical model for the branching bifurcation and perform its unfolding around the loss of evolutionary stability. We cast our analysis in the simplest (but classical) setting of asexual, unstructured populations living in an isolated, homogeneous, and constant abiotic environment; individual traits are one-dimensional; intra- as well as inter-specific ecological interactions are described in the vicinity of a stationary regime.

  9. Biological races in humans.

    Science.gov (United States)

    Templeton, Alan R

    2013-09-01

    Races may exist in humans in a cultural sense, but biological concepts of race are needed to access their reality in a non-species-specific manner and to see if cultural categories correspond to biological categories within humans. Modern biological concepts of race can be implemented objectively with molecular genetic data through hypothesis-testing. Genetic data sets are used to see if biological races exist in humans and in our closest evolutionary relative, the chimpanzee. Using the two most commonly used biological concepts of race, chimpanzees are indeed subdivided into races but humans are not. Adaptive traits, such as skin color, have frequently been used to define races in humans, but such adaptive traits reflect the underlying environmental factor to which they are adaptive and not overall genetic differentiation, and different adaptive traits define discordant groups. There are no objective criteria for choosing one adaptive trait over another to define race. As a consequence, adaptive traits do not define races in humans. Much of the recent scientific literature on human evolution portrays human populations as separate branches on an evolutionary tree. A tree-like structure among humans has been falsified whenever tested, so this practice is scientifically indefensible. It is also socially irresponsible as these pictorial representations of human evolution have more impact on the general public than nuanced phrases in the text of a scientific paper. Humans have much genetic diversity, but the vast majority of this diversity reflects individual uniqueness and not race. PMID:23684745

  10. Herpes - resources

    Science.gov (United States)

    Genital herpes - resources; Resources - genital herpes ... The following organizations are good resources for information on genital herpes : March of Dimes -- www.marchofdimes.com/pregnancy/complications-herpes National Institute of Allergy and Infectious Disease -- ...

  11. Stochastic processes in cell biology

    CERN Document Server

    Bressloff, Paul C

    2014-01-01

    This book develops the theory of continuous and discrete stochastic processes within the context of cell biology.  A wide range of biological topics are covered including normal and anomalous diffusion in complex cellular environments, stochastic ion channels and excitable systems, stochastic calcium signaling, molecular motors, intracellular transport, signal transduction, bacterial chemotaxis, robustness in gene networks, genetic switches and oscillators, cell polarization, polymerization, cellular length control, and branching processes. The book also provides a pedagogical introduction to the theory of stochastic process – Fokker Planck equations, stochastic differential equations, master equations and jump Markov processes, diffusion approximations and the system size expansion, first passage time problems, stochastic hybrid systems, reaction-diffusion equations, exclusion processes, WKB methods, martingales and branching processes, stochastic calculus, and numerical methods.   This text is primarily...

  12. Biology Curriculum Support Document.

    Science.gov (United States)

    North Carolina Dept. of Public Instruction, Raleigh.

    This biology curriculum supplement includes the North Carolina Standard Course of Study Goals, helpful resources, and suggested activities supported by inquiry-based laboratory activities. Contents include a detailed description of content which provides the goals and standards being sough), a materials list for inquiry support labs and…

  13. The specific carbon isotopic compositions of branched and cyclic hydrocarbons from Fushun oil shale

    Institute of Scientific and Technical Information of China (English)

    DUAN Yi; WU Baoxiang; ZHENG Guodong; ZHANG Hui; ZHENG Chaoyang

    2004-01-01

    Various branched and cyclic hydrocarbons are isolated from the Fushun oil shale and their carbon isotopes are determined. The analytical results show that the branched and cyclic hydrocarbons are fully separated from n-alkanes by 5 A Molecular-sieve adduction using long time and cold solvent. The branched and cyclic hydrocarbon fraction obtained by this method is able to satisfy the analytic requests of GC-IRMS. The carbon isotopic compositions of these branched and cyclic hydrocarbons obtained from the sample indicate that they are derived from photoautotrophic algae, chemoautotrophic bacteria (-3.4‰ --39.0‰) and methanotrophic bacteria (-38.4‰--46.3‰). However the long-chain 2-methyl-branched alkanes indicate that their carbon isotopic compositions reflect biological origin from higher plants. The carbon isotopic composition of C30 4-methyl sterane (-22.1‰) is the heaviest in all studied ste- ranes, showing that the carbon source or growth condition for its precursor, dinoflagellate, may be different from that of regular steranes. The variation trend of δ13C values between isomers of hopanes shows that 13C-enriched precursors take precedence in process of their epimerization. Methanotrophic hopanes presented reveal the processes of strong transformation of organic matter and cycling of organic carbon in the water column and early diagenesis of oil shale.

  14. Fast Coalescent-Based Computation of Local Branch Support from Quartet Frequencies.

    Science.gov (United States)

    Sayyari, Erfan; Mirarab, Siavash

    2016-07-01

    Species tree reconstruction is complicated by effects of incomplete lineage sorting, commonly modeled by the multi-species coalescent model (MSC). While there has been substantial progress in developing methods that estimate a species tree given a collection of gene trees, less attention has been paid to fast and accurate methods of quantifying support. In this article, we propose a fast algorithm to compute quartet-based support for each branch of a given species tree with regard to a given set of gene trees. We then show how the quartet support can be used in the context of the MSC to compute (1) the local posterior probability (PP) that the branch is in the species tree and (2) the length of the branch in coalescent units. We evaluate the precision and recall of the local PP on a wide set of simulated and biological datasets, and show that it has very high precision and improved recall compared with multi-locus bootstrapping. The estimated branch lengths are highly accurate when gene tree estimation error is low, but are underestimated when gene tree estimation error increases. Computation of both the branch length and local PP is implemented as new features in ASTRAL. PMID:27189547

  15. The ecological basis of morphogenesis: branching patterns in swarming colonies of bacteria

    International Nuclear Information System (INIS)

    Understanding how large-scale shapes in tissues, organs and bacterial colonies emerge from local interactions among cells and how these shapes remain stable over time are two fundamental problems in biology. Here we investigate branching morphogenesis in an experimental model system, swarming colonies of the bacterium Pseudomonas aeruginosa. We combine experiments and computer simulation to show that a simple ecological model of population dispersal can describe the emergence of branching patterns. In our system, morphogenesis depends on two counteracting processes that act on different length-scales: (i) colony expansion, which increases the likelihood of colonizing a patch at a close distance and (ii) colony repulsion, which decreases the colonization likelihood over a longer distance. The two processes are included in a kernel-based mathematical model using an integro-differential approach borrowed from ecological theory. Computer simulations show that the model can indeed reproduce branching, but only for a narrow range of parameter values, suggesting that P. aeruginosa has a fine-tuned physiology for branching. Simulations further show that hyperswarming, a process where highly dispersive mutants reproducibly arise within the colony and disrupt branching patterns, can be interpreted as a change in the spatial kernel. (paper)

  16. 青海省野薄荷生物学特性及资源储量的研究%Studies on Resource Accumulation and Biological Characteristics of Mentha haplocalyx in Qinghai Province

    Institute of Scientific and Technical Information of China (English)

    刘玉萍; 苏旭

    2011-01-01

    Mentha haplocalyx Briq.is a kind of rare wild medical plant in Qing-Tibet Plateau.The whole plant is the medicine.Thereinto, the volatile oil contained in the overground part has the very important economic and medical value.Meanwhile, it has the long florescence, abundant honey,strongly attrahent bees, green plants, spicy smell and so on, so it is a kind of better honey and flowering plants.But the resource of wild plant decreases markedly because of excessively exploration.That is detrimental to ecological environmental protection of Qing-Tibet Plateau and sustainable utilization and exploitation of medical plant.This article, applying the method of the pointing field, the least sample and statistics, studied biological characteristics, respectively populated botanical characteristics, community and quantity characteristics and resource accumulation of Mentha haplocalyx Briq.in Qinghai Province, and calculated resource accumulation of it.It provided scientific basis for utilization and exploitation of Mentha haplocalyx Briq.in Qinghai province.%野薄荷是青藏高原特有的野生药用植物,全草可以入药,其中地上部分所含的挥发油具有十分重要的经济价值和药用价值.同时,野薄荷由于花期长、泌蜜丰富、诱蜂力强、以及气香株色绿和宿根草本等原因,故也是一种较好的蜜源和花卉植物.但由于过渡开采,使得该野生植物资源量呈显著下降趋势,这对于青藏高原的生态环境保护及药用植物的开发利用都是不利的.采用野外定点法、最小样方法和统计学方法分别对青海省野薄荷的植物学特性、群落数量特征和资源量进行研究,并计算野薄荷的资源储量,旨在为青海省野薄荷资源的保护和合理开发利用提供科学依据.

  17. Photovoltaic Program Branch annual report, FY 1989

    Energy Technology Data Exchange (ETDEWEB)

    Summers, K A [ed.

    1990-03-01

    This report summarizes the progress of the Photovoltaic (PV) Program Branch of the Solar Energy Research Institute (SERI) from October 1, 1988, through September 30, 1989. The branch is responsible for managing the subcontracted portion of SERI's PV Advanced Research and Development Project. In fiscal year (FY) 1989, this included nearly 50 subcontracts, with a total annualized funding of approximately $13.1 million. Approximately two-thirds of the subcontracts were with universities, at a total funding of nearly $4 million. The six technical sections of the report cover the main areas of the subcontracted program: Amorphous Silicon Research, Polycrystalline Thin Films, Crystalline Silicon Materials Research, High-Efficiency Concepts, New Ideas, and University Participation. Technical summaries of each of the subcontracted programs provide a discussion of approaches, major accomplishments in FY 1989, and future research directions. Each report will be cataloged individually.

  18. Branch management into micropipeline joint dot

    Directory of Open Access Journals (Sweden)

    Dimitar Tyanev

    2011-11-01

    Full Text Available This paper considers problems related to hardware implementation of computational process with conditional jumps. Hardware refers to asynchronous pipeline organization at microoperational level. Exploration is dedicated to one of the tasks presented in (Tyanev, D., 2009 concerning to micropipeline controller design to control micropipeline stage into joint dot of branch algorithm. Joint dot is the point at which few preceding branches are combined. It appears inevitably into conditional jump structures and this is the reason for the actuality of its problem. Analysis of this new task is presented and request arbitration functioning principles are formulated for the incoming to joint dot requests. The arbiter is responsible for the fair choice on which depends steady peformance of separate pipeline brances. Paper also describes pipeline controller synthesis and analysis of its operation in two variants: about 2-phase and 4-phase data transfer protocol. The synthesized asynchronous arbiter scheme is invariant to the type of pipeline protocol.

  19. Branching Dynamics of Viral Information Spreading

    CERN Document Server

    Iribarren, José Luis

    2011-01-01

    Despite its importance for rumors or innovations propagation, peer-to-peer collaboration, social networking or Marketing, the dynamics of information spreading is not well understood. Since the diffusion depends on the heterogeneous patterns of human behavior and is driven by the participants' decisions, its propagation dynamics shows surprising properties not explained by traditional epidemic or contagion models. Here we present a detailed analysis of our study of real Viral Marketing campaigns where tracking the propagation of a controlled message allowed us to analyze the structure and dynamics of a diffusion graph involving over 31,000 individuals. We found that information spreading displays a non-Markovian branching dynamics that can be modeled by a two-step Bellman-Harris Branching Process that generalizes the static models known in the literature and incorporates the high variability of human behavior. It explains accurately all the features of information propagation under the "tipping-point" and can...

  20. General collision branching processes with two parameters

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    A new class of branching models,the general collision branching processes with two parameters,is considered in this paper.For such models,it is necessary to evaluate the absorbing probabilities and mean extinction times for both absorbing states.Regularity and uniqueness criteria are firstly established.Explicit expressions are then obtained for the extinction probability vector,the mean extinction times and the conditional mean extinction times.The explosion behavior of these models is investigated and an explicit expression for mean explosion time is established.The mean global holding time is also obtained.It is revealed that these properties are substantially different between the super-explosive and sub-explosive cases.

  1. Computers in Some Branches of Applied Physiology .

    Directory of Open Access Journals (Sweden)

    S.S. Verma

    1994-04-01

    Full Text Available This paper reviews the applications of computers in the evaluation of different types of problems occuring in some branches of applied physiology. The recent applications of computers to perform advanced multivariate regression analysis for developing regression models in applied physiology are also highlighted. The regression models are practical significance for screening personnel in defence services, mines, industrial works, sports and the like.

  2. Minimum disparity estimation in controlled branching processes

    OpenAIRE

    Gonzalez, Miguel; Minuesa, Carmen; del Puerto, Ines

    2015-01-01

    Minimum disparity estimation in controlled branching processes is dealt with by assuming that the offspring law belongs to a general parametric family. Under some regularity conditions it is proved that the minimum disparity estimators proposed -based on the nonparametric maximum likelihood estimator of the offspring law when the entire family tree is observed- are consistent and asymptotic normally distributed. Moreover, it is discussed the robustness of the estimators proposed. Through a si...

  3. Branch Retinal Vein Occlusion and Its Management

    Institute of Scientific and Technical Information of China (English)

    Desmond; Archer

    1992-01-01

    The natural course of Branch Retinal Vein Occlusion is determined by the site and completeness of the occlusion, the integrity of arterial perfusion to the affected sector and the efficiency of the developing collateral circulation. Most patients with tributary vein occlusion have some capillary fall out and microvascular incompetence in the distribution of the affected retina and vision is significantly compromised in over 50% of patients who have either chronic macular oedema or ischemia involving the...

  4. Recursive algorithms, branching coefficients and applications

    CERN Document Server

    Lyakhovsky, Vladimir

    2010-01-01

    Recurrent relations for branching coefficients in affine Lie algebras integrable highest weight modules are studied. The decomposition algorithm based on the injection fan technique is adopted to the situation where the Weyl denominator becomes singular with respect to a reductive subalgebra. We study some modifications of the injection fan technique and demonstrate that it is possible to define the "subtracted fans" that play the role similar to the original ones. Possible applications of subtracted fans in CFT models are considered.

  5. [Geometry and algebra of branches of the middle cerebral artery].

    Science.gov (United States)

    Blinkov, S M

    1986-01-01

    A classification of the cortical branches of the middle cerebral artery (MCA) is suggested by means of which each branch in any hemisphere can be qualified and identified in any variant of MCA branching. The principle of the classification consists in grouping the branches into arteries and trunks of the second, third, etc. order. Branches supplying blood to a certain sector of the lateral surface of the hemisphere are designated arteries. Their number and zone of branching are constant. Branches giving rise to 2 and more arteries are named trunks. Branching of the trunks, the number of trunks of the second, third, etc. order, and the site and type of origin of the arteries are extremely variable. Each trunk can be designated by a formula stating its order and the name of the artery supplied by this trunk. The arrangement of the MCA branches on the surface of the gyri and deep in the sulci, represented on the map of the lateral surface of the hemisphere, is designated conditionally as geometry of MCA branches. The order of branching of the trunks and the type of origin of the arteries, represented on abstract maps of the lateral surface of the hemisphere, are designated conditionally as algebra of the MCA branches. The variability of the geometry and algebra of the MCA branches must be taken into consideration in operations for extra-intracranial microanastomosis and in endovasal intervention on the MCA. PMID:3811741

  6. Measurements of $\\Xi_c^{+}$ Branching Ratios

    CERN Document Server

    Link, J M; Anjos, J C; Bediaga, I; Göbel, C; Magnin, J; Massafferri, A; De Miranda, J M; Pepe, I M; Polycarpo, E; Dos Reis, A C; Carrillo, S; Casimiro, E; Cuautle, E; Sánchez-Hernández, A; Uribe, C; Vázquez, F; Agostino, L; Cinquini, L; Cumalat, J P; O'Reilly, B; Segoni, I; Wahl, M; Butler, J N; Cheung, H W K; Chiodini, G; Gaines, I; Garbincius, P H; Garren, L A; Gottschalk, E E; Kasper, P H; Kreymer, A E; Kutschke, R; Wang, M; Benussi, L; Bertani, M; Bianco, S; Fabbri, Franco Luigi; Zallo, A; Reyes, M; Cawlfield, C; Kim, D Y; Rahimi, A; Wiss, J; Gardner, R; Kryemadhi, A; Chung, Y S; Kang, J S; Ko, B R; Kwak, J W; Lee, K B; Cho, K; Park, H; Alimonti, G; Barberis, S; Boschini, M; Cerutti, A; D'Angelo, P; Di Corato, M; Dini, P; Edera, L; Erba, S; Giammarchi, M; Inzani, P; Leveraro, F; Malvezzi, S; Menasce, D; Mezzadri, M; Moroni, L; Pedrini, D; Pontoglio, C; Prelz, F; Rovere, M; Sala, S; Davenport, T F; Arena, V; Boca, G; Bonomi, G; Gianini, G; Liguori, G; Lopes-Pegna, D; Merlo, M M; Pantea, D; Ratti, S P; Riccardi, C; Vitulo, P; Hernández, H; López, A M; Luiggi, E; Méndez, H; Paris, A; Quinones, J; Ramírez, J E; Zhang, Y; Wilson, J R; Handler, T; Mitchell, R; Engh, D; Hosack, M; Johns, W E; Nehring, M S; Sheldon, P D; Stenson, K; Vaandering, E W; Webster, M; Sheaff, M

    2003-01-01

    Using data collected by the fixed target Fermilab experiment FOCUS, we measure the branching ratios of the Cabibbo favored decays $\\Xi_c^+ \\to \\Sigma^+K^-\\pi^+$, $\\Xi_c^+ \\to \\Sigma^+ \\bar{K}^{*}(892)^0$, and $\\Xi_c^+ \\to \\Lambda^0K^-\\pi^+\\pi^+$ relative to $\\Xi_c^+ \\to \\Xi^-\\pi^+\\pi^+$ to be $0.91\\pm0.11\\pm0.04$, $0.78\\pm0.16\\pm0.06$, and $0.28\\pm0.06\\pm0.06$, respectively. We report the first observation of the Cabibbo suppressed decay $\\Xi_c^+ \\to \\Sigma^+K^+K^-$ and we measure the branching ratio relative to $\\Xi_c^+ \\to \\Sigma^+K^-\\pi^+$ to be $0.16\\pm0.06\\pm0.01$. We also set 90% confidence level upper limits for $\\Xi_c^+ \\to \\Sigma^+ \\phi$ and $\\Xi_c^+ \\to \\Xi^*(1690)^0(\\Sigma^+ K^-) K^+$ relative to $\\Xi_c^+ \\to \\Sigma^+K^-\\pi^+$ to be 0.12 and 0.05, respectively. We find an indication of the decays $\\Xi_c^+ \\to \\Omega^-K^{+}\\pi^+$ and $\\Xi_c^+ \\to \\Sigma^{*}(1385)^+ \\bar{K}^0$ and set 90% confidence level upper limits for the branching ratios with respect to $\\Xi_c^+ \\to \\Xi^-\\pi^+\\pi^+$ to be 0.12 a...

  7. Functional morphology, biomechanics and biomimetic potential of stem–branch connections in Dracaena reflexa and Freycinetia insignis

    Directory of Open Access Journals (Sweden)

    Tom Masselter

    2011-03-01

    Full Text Available Branching in plants is one of the most important assets for developing large arborescent growth forms with complex crowns. While the form and development of branching in gymnosperms and dicotyledonous trees is widely understood, very little is known about branching patterns and the structure of branch–stem-junctions in arborescent monocotyledons. For a better and quantitative understanding of the functional morphology of branch–stem-junctions in arborescent monocotyledons, we investigated the two species Dracaena reflexa and Freycinetia insignis. While D. reflexa is able to develop large arborescent forms with conspicuous crowns by anomalous secondary growth, F. insignis remains relatively small and is only capable of primary growth. Biomechanical investigations were performed by applying vertical loads up to rupture to lateral branches of both species. This allows the analysis of the fracture mechanics and the determination of the maximal force, stress and strain at rupture as well as the fracture toughness. Functional morphology was correlated with the mechanical behaviour of these plants and compared to data of other dicotyledonous trees. The high energy absorption found in the rupture process of lateral branches of D. reflexa and F. insignis makes them promising biological concept generators with a high potential for biomimetic implementation, i.e., for the development of branched fibre-reinforced technical composites. A wide range of constructional elements with branched (sub-structures can be optimised by using solutions inspired by plant ramifications, e.g., in automotive and aerospace engineering, architecture, sports equipment and prosthetic manufacturing.

  8. Folding and unfolding of a triple-branch DNA molecule with four conformational states

    OpenAIRE

    Engel, Sandra; Alemany, Anna; Forns, Nuria; Maass, Philipp; Ritort, Felix

    2011-01-01

    Abstract Single-molecule experiments provide new insights into biological processes hitherto not accessible by measurements performed on bulk systems. We report on a study of the kinetics of a triple-branch DNA molecule with four conformational states by pulling experiments with optical tweezers and theoretical modelling. Three distinct force rips associated with different transitions between the conformational states are observed in the folding and unfolding t...

  9. Third annual Walker Branch Watershed research symposium. Program and abstracts

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    The methods and concepts of watershed research, originally applied in an experimental or monitoring mode to relatively small catchments, are increasingly being used at larger scales and for specific applied problems. Research at Oak Ridge National Laboratory, the Tennessee Valley Authority, the US Forest Service, and other agencies and institutions participating in this symposium reflects research over a broad range of spatial scales that is being integrated through large-scale experiments along with computer modeling and graphical interfaces. These research projects address the basic atmospheric, geophysical, biogeochemical, and biological processes that regulate the responses of forested ecosystems to natural environmental variation and anthropogenic stresses. Regional and global issues addressed by presentations include emissions of carbon dioxide, methane, and other hydrocarbons; deposition of sulfate, nitrate, and mercury; land-use changes; biological diversity; droughts; and water quality. The reports presented in this symposium illustrate a wide range of methods and approaches and focus more on concepts and techniques than on a specific physical site. Sites and projects that have contributed research results to this symposium include Walker Branch Watershed (DOE), the Coweeta Hydrologic Laboratory and LTER site (USFS and NSF), Great Smoky Mountains National Park (research funded by NPS, TVA, and EPRI), Imnavait Creek, Alaska (DOE), the TVA-Norris Whole-tree Facility (TVA and EPRI), and DOE`s Biomass Program.

  10. Effect of Different Growing Systems of Apple on Trunk and Branch Diseases and Pests

    Directory of Open Access Journals (Sweden)

    Maria BOROVINOVA

    2012-11-01

    Full Text Available The presented study aimed to determine apples trunk and branch diseases and pests in three growing systems conventional, integrated and biological (organic. The investigations were made on an experimental apple orchard (1 ha of the Institute of Agriculture at Kyustendil, Southwest Bulgaria in four consecutive years from 2007 to 2010. Three scab resistant cultivars Prima, Florina and Erwin Baur grafted on rootstocks MM106 were planted in 1996. The orchard was divided into four plots. One plot was treated conventionally with a normal pesticide programme, two plots were treated integrated according to the general principles, rules and standards of integrated apple production and one plot for biological (organic. The monitoring of pests and diseases and assessment of their density were done every two weeks. It was established that during the experimental period important disease and pests on apple trees in different growing systems were black rot Botryosphaeria obtusa, apple clearwig moth Synanthedon myopaeformis and shorthole borer Scolytus rugulosus. The damages by trunk and branch diseases and pests on apple were considerable higher in biological growing system. The mean rate of attack of cultivar Erwin Baur by Botryosphaeria obtusa in biological and conventional growing systems was 52.35% and 4.65%, respectively. The percentage of damaged by Scolytus rugulosus trunk and branch area per tree reach to 58.74 in biological and 0.23 in conventional system. Reduced vitality of apple trees growing with out pesticides and mineral fertilizers in biological growing system was the reason for strong infection of Botryosphaeria obtusa and attack of Synanthedon myopaeformis and Scolytus rugulosus.

  11. Differentiation of crack branching types in fractured glass

    Science.gov (United States)

    Rabinovitch, A.; Bahat, D.

    2011-07-01

    The influence of different physical factors on the fracture branching phenomenon was investigated on a fractured brittle (glass) bottle. A fully branched fracture tree consisting of 144 initiation sites was induced. Branching sites were concentrated in two zones: close to the fracture origin and further away from it along the bottle axis, which was shown to be related to reflection of transverse acoustic waves from the bottle's shoulder. Two types of branching formed, complete full branches (FB), and attempted branching (AB) when one branch was shorter than 5 mm. Branching in the first zone was shown to be regulated by both the distribution of flaw lengths and the distances from each FB to its nearest fracture neighbor. Fracture spacing was found to be proportional to the stress at the propagating fracture tips.

  12. Evaluation of allowable external pressure for branch pipe connections

    International Nuclear Information System (INIS)

    Although the allowable external pressure for branch pipe connections is estimated by evaluation procedure for straight pipe, the applicability of this procedure has not been clear. That was discussed in this study. The buckling pressure of branch pipe connections was estimated by linear eigenvalue analysis with FEA (Finite Element Analysis). The types of branch pipe connections were T-joints and T-pipes. The ranges of configurations in branch pipe connections for FEA were determined by survey of branch pipe connections in the Japanese nuclear power plants. The results of the FEA showed that the buckling strength of branch pipe was found sufficiently to be superior to that of straight piping from comparisons of estimations by FEA for branch pipe connections and those by formula for straight pipe in the design code. It was concluded that the formula for straight pipe is applicable for the evaluation of allowable external pressure for branch pipe connections. (author)

  13. Groundwater availability in the Crouch Branch and McQueen Branch aquifers, Chesterfield County, South Carolina, 1900-2012

    Science.gov (United States)

    Campbell, Bruce G.; Landmeyer, James E.

    2014-01-01

    Chesterfield County is located in the northeastern part of South Carolina along the southern border of North Carolina and is primarily underlain by unconsolidated sediments of Late Cretaceous age and younger of the Atlantic Coastal Plain. Approximately 20 percent of Chesterfield County is in the Piedmont Physiographic Province, and this area of the county is not included in this study. These Atlantic Coastal Plain sediments compose two productive aquifers: the Crouch Branch aquifer that is present at land surface across most of the county and the deeper, semi-confined McQueen Branch aquifer. Most of the potable water supplied to residents of Chesterfield County is produced from the Crouch Branch and McQueen Branch aquifers by a well field located near McBee, South Carolina, in the southwestern part of the county. Overall, groundwater availability is good to very good in most of Chesterfield County, especially the area around and to the south of McBee, South Carolina. The eastern part of Chesterfield County does not have as abundant groundwater resources but resources are generally adequate for domestic purposes. The primary purpose of this study was to determine groundwater-flow rates, flow directions, and changes in water budgets over time for the Crouch Branch and McQueen Branch aquifers in the Chesterfield County area. This goal was accomplished by using the U.S. Geological Survey finite-difference MODFLOW groundwater-flow code to construct and calibrate a groundwater-flow model of the Atlantic Coastal Plain of Chesterfield County. The model was created with a uniform grid size of 300 by 300 feet to facilitate a more accurate simulation of groundwater-surface-water interactions. The model consists of 617 rows from north to south extending about 35 miles and 884 columns from west to east extending about 50 miles, yielding a total area of about 1,750 square miles. However, the active part of the modeled area, or the part where groundwater flow is simulated

  14. Biological computation

    CERN Document Server

    Lamm, Ehud

    2011-01-01

    Introduction and Biological BackgroundBiological ComputationThe Influence of Biology on Mathematics-Historical ExamplesBiological IntroductionModels and Simulations Cellular Automata Biological BackgroundThe Game of Life General Definition of Cellular Automata One-Dimensional AutomataExamples of Cellular AutomataComparison with a Continuous Mathematical Model Computational UniversalitySelf-Replication Pseudo Code Evolutionary ComputationEvolutionary Biology and Evolutionary ComputationGenetic AlgorithmsExample ApplicationsAnalysis of the Behavior of Genetic AlgorithmsLamarckian Evolution Genet

  15. Calcium as a branching signal in Neurospora crassa.

    OpenAIRE

    Reissig, J L; Kinney, S G

    1983-01-01

    The divalent cation ionophore A23187 was found to induce apical branching in Neurospora crassa. Optimal effects were obtained by treatment with 0.1 mM ionophore for 30 min. Branching first became manifest during or shortly after treatment; successive rounds of branching could be observed at later times. Calcium starvation of the mycelium markedly reduced its subsequent response to the ionophore, whereas starvation for other divalent cations had no detectable effect. The branching response was...

  16. Characterizing Weighted MSO for Trees by Branching Transitive Closure Logics

    OpenAIRE

    Fülöp, Zoltán; Vogler, Heiko

    2012-01-01

    We introduce the branching transitive closure operator on weighted monadic second-order logic formulas where the branching corresponds in a natural way to the branching inherent in trees. For arbitrary commutative semirings, we prove that weighted monadic second order logics on trees is equivalent to the definability by formulas which start with one of the following operators: (i) a branching transitive closure or (ii) an existential second-order quantifier followed by one universal first-ord...

  17. Statistics of branched flow in a weak correlated random potential

    OpenAIRE

    Kaplan, Lev

    2002-01-01

    Recent images of electron flow through a two-dimensional electron gas (2DEG) device show branching behavior that is reproduced in numerical simulations of motion in a correlated random potential [cond-mat/0010348]. We show how such branching naturally arises from caustics in the classical flow and find a simple scaling behavior of the branching under variation of the random potential strength. Analytic results describing the statistical properties of the branching are confirmed by classical a...

  18. Biological and Geographical application tool

    OpenAIRE

    Pereira, Miguel

    2007-01-01

    Monitoring and species identify is an essential step to natural resources management. Among these, biological resources aim special concern because data availability is highly limited by a number of sampling logistic constraints and catalog. As a matter of fact, data availability is one of important limitation to knowledge and, as a consequence the development of a new concept in natural resources. Data organization in digital format is a common practice in our days, and has the power to cont...

  19. Grand challenges in space synthetic biology.

    Science.gov (United States)

    Menezes, Amor A; Montague, Michael G; Cumbers, John; Hogan, John A; Arkin, Adam P

    2015-12-01

    Space synthetic biology is a branch of biotechnology dedicated to engineering biological systems for space exploration, industry and science. There is significant public and private interest in designing robust and reliable organisms that can assist on long-duration astronaut missions. Recent work has also demonstrated that such synthetic biology is a feasible payload minimization and life support approach as well. This article identifies the challenges and opportunities that lie ahead in the field of space synthetic biology, while highlighting relevant progress. It also outlines anticipated broader benefits from this field, because space engineering advances will drive technological innovation on Earth. PMID:26631337

  20. Grand challenges in space synthetic biology.

    Science.gov (United States)

    Menezes, Amor A; Montague, Michael G; Cumbers, John; Hogan, John A; Arkin, Adam P

    2015-12-01

    Space synthetic biology is a branch of biotechnology dedicated to engineering biological systems for space exploration, industry and science. There is significant public and private interest in designing robust and reliable organisms that can assist on long-duration astronaut missions. Recent work has also demonstrated that such synthetic biology is a feasible payload minimization and life support approach as well. This article identifies the challenges and opportunities that lie ahead in the field of space synthetic biology, while highlighting relevant progress. It also outlines anticipated broader benefits from this field, because space engineering advances will drive technological innovation on Earth.

  1. Theoretical prediction of side branch compromise after main branch stenting in coronary bifurcation

    Institute of Scientific and Technical Information of China (English)

    Dobrin Vassilev; Robert Gil

    2008-01-01

    One of the main problems of treatment of bifurcation lesions is side branch (SB) stenosis appearing after stent placement in the main vessel.The aim of this study was to create quantitative method for prediction of side branch compromise extent.We accepted that the main mechanism for SB ostial stenosis is flow divider (FD) displacement from stent struts after stent implantation in the main vessel.Using easily measurable parameters from coronary angiography,as SB diameter,angle α (initial angle between axes of parent vessel and SB axis) and angle α' (angle between above mentioned axes after stent placement) we can calculate percentage diameter stenosis at branch ostium (%DS):%DS = sin (α - α')/(tan α).In boundary condition of full FD displacement %DS = cos α.We tested our theoretical predictions with fluoroscopic observation of elastic wall model of bifurcation (45°distal angle between branches)permitting wall deformations with stent.There is full coincidence of values of %DS and percentage area stenosis (%AS).The regular formulas for calculations of %DS and %AS overestimate stenosis severity between 10% and 25%.Our model tests have shown full coincidence between predicted values for %DS and observed values.We demonstrate that part of the SB ostium is not visible in regular angiography and contributes to ostial lumen area.This is a method that permits quantitative prediction of side branch compromise.

  2. 40 CFR 721.10094 - Decene, branched and linear.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Decene, branched and linear. 721.10094... Substances § 721.10094 Decene, branched and linear. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as decene, branched and linear (PMN P-03-272;...

  3. Catalytic production of branched small alkanes from biohydrocarbons.

    Science.gov (United States)

    Oya, Shin-ichi; Kanno, Daisuke; Watanabe, Hideo; Tamura, Masazumi; Nakagawa, Yoshinao; Tomishige, Keiichi

    2015-08-10

    Squalane, C30 algae-derived branched hydrocarbon, was successfully converted to smaller hydrocarbons without skeletal isomerization and aromatization over ruthenium on ceria (Ru/CeO2 ). The internal CH2 CH2 bonds located between branches are preferably dissociated to give branched alkanes with very simple distribution as compared with conventional methods using metal-acid bifunctional catalysts.

  4. Structural dynamics branch research and accomplishments to FY 1992

    Science.gov (United States)

    Lawrence, Charles

    1992-12-01

    This publication contains a collection of fiscal year 1992 research highlights from the Structural Dynamics Branch at NASA LeRC. Highlights from the branch's major work areas--Aeroelasticity, Vibration Control, Dynamic Systems, and Computational Structural Methods are included in the report as well as a listing of the fiscal year 1992 branch publications.

  5. Nuclear Science and Technology Branch Report 1975

    International Nuclear Information System (INIS)

    A summary is given of research activities. These include: nuclear techniques of analysis, nuclear techniques in hydrology, industrial applications of radioisotopes, biological and chemical applications of irradiation, radiation detection and measurement, environmental studies and biophysics and radiation biology. Patent applications and staff of the nuclear science and applications secretariat are listed. (R.L.)

  6. On the Edge of Mathematics and Biology Integration: Improving Quantitative Skills in Undergraduate Biology Education

    OpenAIRE

    Feser, Jason; Vasaly, Helen; Herrera, Jose

    2013-01-01

    The feature describes two major efforts to integrate mathematics and biology. A call is made to biologists to consider the need to address biology undergraduate education changes and to use the resources described.

  7. FY 1997 report on the results of the industrial technology R and D project. Development of technology to use biological resources such as the complex biological system (Development of biological use petroleum substitution fuel production technology); 1997 nendo fukugo seibutsukei nado seibutsu shigen riyo gijutsu kaihatsu seika hokokusho. Seibutsu riyo sekiyu daitai nenryo seizo gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Experimental researches were conducted and the FY 1997 results were reported with the aim of establishing analytical technology for the complex biological system by which the complex biological system can be analyzed in such a state as it is using the molecular biological method. In the study of the molecular genetic analytical technology, PCR primers used for amplification of topoisomerase II genes of the whole eukaryote was designed. As to the histochemical analytical technology, a study was made on the new constitution microorganism detection method by the hybridization method and the antibody specific dyeing method, and the following were conducted: manifestation in quantity of colibacillus and the recovery, refining, and construction of peptide library by fuzzy display method. Concerning the functional analytical technology, technological researches were made such as the environmental adaptation mechanism of high thermophile and the information transfer mechanism among bacteria through cell membranes for elucidation of the special environment detection/response mechanism and the special environment adaptation/resistance mechanism. As to the separation/culture technology, various anaerobic microorganisms were separated from marine sponge for the development of a method of culturing in 3D matrices. (NEDO)

  8. Geology of the Cane Branch and Helton Branch watershed areas, McCreary County, Kentucky

    Science.gov (United States)

    Lyons, Erwin J.

    1957-01-01

    Cane Branch and Helton Branch in McCreary County, Kentucky, are about 1.4 miles apart (fig. 1). Can Branch, which is about 2.1 miles long, emptied into Hughes Fork of Beaver Creek. Its watershed area of about 1.5 square miles lies largely in the Wiborf 7 1/2-minute quadrangle (SW/4 Cumberland Falls 15-minute quadrangle), but the downstream part of the area extends northward into the Hail 7 1/2-minute quadrangle (NW/4 Cumberland Falls 15-minute quadrangle). Helton Branch, which is about 1.1 miles long, has two tributaries and empties into Little Hurricane Fork of Beaver Creek. It drains an area of about 0.8 square mile of while about 0.5 square mile is in the Hail quadrangle and the remainder in the Wilborg quadrangle. The total relief in the Can Branch area is about 500 feet and in the Helton Branch area about 400 feet. Narrow, steep-sided to canyon-like valley and winding ridges, typical of the Pottsville escarpment region, are characteristic of both areas. Thick woods and dense undergrowth cover much of the two areas. Field mapping was done on U.S. Geological Survey 7 1/2-minute maps having a scale of 1:24,000 and a contour interval of 20 feet. Elevations of lithologic contacts were determined with a barometer and a hand level. Aerial photographs were used principally to trace the cliffs formed by sandstone and conglomerate ledges. Exposures, except for those of the cliff- and ledge-forming sandstone and conglomerates, are not abundant. The most complete stratigraphic sections (secs. 3 and 4, fig. 2) in the two areas are exposed in cuts of newly completed Forest Service roads, but the rick in the upper parts of the exposures is weathered. To supplement these sections, additional sections were measured in cuts along the railroad and main highways in nor near the watersheds.

  9. Organization and targets of the European Branch

    Energy Technology Data Exchange (ETDEWEB)

    Cataldi, R.

    1997-12-01

    After a short historical review of the formation, objectives and organization of the International Geothermal Association (IGA), this paper describes the functions, goals and activities of the IGA European Branch. In particular, the paper illustrates the plan of action established for the periods 1993-`95 and 1996-`98, and the issues dealt with by the European Forum as of August 1996. The last section of the paper outlines the main problems to be faced in the near future in order to facilitate the aggregation of efforts, the amalgamation of promotional initiatives and the coordination of the basic activities needed for the consolidation and growth of the geothermal community in Europe. (orig.)

  10. Branching of periodic orbits from Kukles isochrones

    Directory of Open Access Journals (Sweden)

    B. Toni

    1998-05-01

    Full Text Available We study local bifurcations of limit cycles from isochronous (or linearizable centers. The isochronicity has been determined using the method of Darboux linearization, which provides a birational linearization for the examples that we analyze. This transformation simplifies the analysis by avoiding the complexity of the Abelian integrals appearing in other approaches. As an application of this approach, we show that the Kukles isochrone (linear and nonlinear has at most one branch point of limit cycles. Moreover, for each isochrone, there are small perturbations with exactly one continuous family of limit cycles.

  11. Annual report, Basic Sciences Branch, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1990, through September 30, 1991. Seven technical sections of the report cover these main areas of NREL's in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, Solid-State Spectroscopy, and Superconductivity. Each section explains the purpose and major accomplishments of the work in the context of the US Department of Energy's National Photovoltaic Research Program plans.

  12. Branch Processes of Regular Magnetic Monopole

    Institute of Scientific and Technical Information of China (English)

    MO Shu-Fan; REN Ji-Rong; ZHU Tao

    2009-01-01

    In this paper, by making use of Duan's topological current theory, the branch process of regular magnetic monopoles is discussed in detail Regular magnetic monopoles are found generating or annihilating at the limit point and encountering, splitting, or merging at the bifurcation point and the degenerate point systematically of the vector order parameter field φ(x).Furthermore, it is also shown that when regular magnetic monopoles split or merge at the degenerate point of field function φ, the total topological charges of the regular magnetic monopoles axe still unchanged.

  13. Annual report, Materials Science Branch, FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Padilla, S. [ed.

    1993-10-01

    This report summarizes the progress of the Materials Science Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1991, through September 30, 1992. Six technical sections of the report cover these main areas of NREL`s in-house research: Crystal Growth, Amorphous Silicon, III-V High-Efficiency Photovoltaic Cells, Solid State Theory, Solid State Spectroscopy, and Program Management. Each section explains the purpose and major accomplishments of the work in the context of the US Department of Energy`s National Photovoltaic Research Program plans.

  14. Annual report, Basic Sciences Branch, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1990, through September 30, 1991. Seven technical sections of the report cover these main areas of NREL`s in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, Solid-State Spectroscopy, and Superconductivity. Each section explains the purpose and major accomplishments of the work in the context of the US Department of Energy`s National Photovoltaic Research Program plans.

  15. Logic, planning agency and branching time

    OpenAIRE

    Ricardo Souza Silvestre

    2010-01-01

    The purpose of this paper is to give a formal account of a kind of agency so far neglected in the field of philosophical modal logic of action: planning agency. In doing this we follow the standard approach of modal logics of agency exemplified by the works of Belnap, Chellas and Pörn. Since we believe there is a close relation between planning, time and indeterminism, we use the theory of branching time as a conceptual framework for investigating the basic features of planning agency. Beside...

  16. Accelerator Physics Branch annual technical report, 1989

    International Nuclear Information System (INIS)

    The report describes, in a series of separate articles, the achievements of the Accelerator Physics Branch for the calendar year 1989. Work in basic problems of accelerator physics including ion sources, high-duty-factor rf quadrupoles, coupling effects in standing wave linacs and laser acceleration is outlined. A proposal for a synchrotron light source for Canada is described. Other articles cover the principal design features of the IMPELA industrial electron linac prototype, the cavities developed for the HERA complex at DESY, Hamburg, West Germany, and further machine projects that have been completed

  17. Optimizing energy transfer efficiency in highly branched nanoplasmonic waveguides

    Science.gov (United States)

    Voronine, Dmitri; Traverso, Andrew; Wang, Kai; Yi, Zhenhuan; Sokolov, Alexei

    2011-03-01

    Energy transfer in highly branched nanoplasmonic particle waveguides is simulated and optimized by varying the waveguide branching geometry and composition. The periodically branched nanostructures provide a new route towards efficient nanoscale light concentration and local field enhancement. On the one hand, they mimick the analogous randomly branched plasmonic nanostructures which have been previously used for surface-enhanced optical spectroscopy such as SERS. On the other hand, the design is inspired by branched molecular aggregates used for energy funneling. The proposed nanostructures may find applications in sensing, light harvesting and nanophotonics.

  18. Scleroderma - resources

    Science.gov (United States)

    Resources - scleroderma ... The following organizations are good resources for information on scleroderma : American College of Rheumatology -- www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/scleroderma.asp National Institute ...

  19. Alzheimer - resources

    Science.gov (United States)

    Resources - Alzheimer ... The following organizations are good resources for information on Alzheimer disease : Alzheimer's Association -- www.alz.org Alzheimer's Disease Education and Referral Center -- www.nia.nih.gov/alzheimers ...

  20. Cancer - resources

    Science.gov (United States)

    Resources - cancer ... The following organizations are good resources for information on cancer : American Cancer Society -- www.cancer.org Cancer Care -- www.cancercare.org National Cancer Institute -- www.cancer.gov

  1. Psoriasis - resources

    Science.gov (United States)

    Resources - psoriasis ... The following organizations are good resources for information about psoriasis : American Academy of Dermatology -- www.aad.org/skin-conditions/dermatology-a-to-z/psoriasis National Institute of ...

  2. Alcoholism - resources

    Science.gov (United States)

    Resources - alcoholism ... The following organizations are good resources for information on alcoholism : Alcoholics Anonymous -- www.aa.org Al-Anon/Alateen -- www.al-anon.org/home National Institute on Alcohol ...

  3. Breastfeeding - resources

    Science.gov (United States)

    Resources - breastfeeding ... The following organizations are good resources for information on breastfeeding and breastfeeding problems : La Leche League International Inc. -- www.lalecheleague.org March of Dimes -- www.marchofdimes.com/ ...

  4. Infertility - resources

    Science.gov (United States)

    Resources - infertility ... The following organizations are good resources for information on infertility : Centers for Disease Control and Prevention -- www.cdc/gov/reproductivehealth/infertility March of Dimes -- www.marchofdimes.com/ ...

  5. Epilepsy - resources

    Science.gov (United States)

    Resources - epilepsy ... The following organizations are good resources for information on epilepsy : Epilepsy Foundation -- www.efa.org National Institute of Neurologic Disorders and Stroke -- www.ninds.nih.gov/disorders/ ...

  6. Incontinence - resources

    Science.gov (United States)

    Resources - incontinence ... The following organizations are good resources for information on incontinence. Fecal incontinence : The American Congress of Obstetricians and Gynecologists -- www.acog.org/~/media/for%20patients/faq139.ashx ...

  7. ALS - resources

    Science.gov (United States)

    Resources - ALS ... The following organizations are good resources for information on amyotrophic lateral sclerosis : Muscular Dystrophy Association -- mda.org/disease/amyotrophic-lateral-sclerosis National Amyotrophic Lateral Sclerosis (ALS) Registry -- ...

  8. Scoliosis - resources

    Science.gov (United States)

    Resources - scoliosis ... The following organizations are good resources for information on scoliosis : American Academy of Orthopedic Surgeons -- orthoinfo.aaos.org/topic.cfm?topic=A00626 National Institute of Arthritis and ...

  9. Lupus - resources

    Science.gov (United States)

    Resources - lupus ... The following organizations are good resources for information on systemic lupus erythematosus : The Lupus Foundation of America -- www.lupus.org The National Institute of Arthritis and Musculoskeletal ...

  10. Migraine - resources

    Science.gov (United States)

    Resources - migraine ... The following organizations are good resources for information on migraines : American Migraine Foundation -- www.americanmigrainefoundation.org National Headache Foundation -- www.headaches.org National Institute of Neurological Disorders ...

  11. SIDS - resources

    Science.gov (United States)

    Resources - SIDS ... The following organizations are good resources for information on SIDS : American SIDS Institute -- www.sids.org Centers for Disease Control and Prevention -- www.cdc.gov/sids National ...

  12. Blindness - resources

    Science.gov (United States)

    Resources - blindness ... The following organizations are good resources for information on blindness : American Foundation for the Blind -- www.afb.org Foundation Fighting Blindness -- www.blindness.org National Eye Institute -- ...

  13. Ostomy - resources

    Science.gov (United States)

    Resources - ostomy ... The following organizations are good resources for information on ostomies: American Society of Colon and Rectal Surgeons -- www.fascrs.org/patients/treatments-screening and www.fascrs.org/ ...

  14. Study on the sustainable utilization of biological and tourist resources in Mt.Luofushan of Guangdong Province%广东罗浮山生物资源和旅游资源永续利用的探讨

    Institute of Scientific and Technical Information of China (English)

    徐颂军

    2001-01-01

    some suggestions about the long-term utilization of biological and tourist resources of Mt. Luofushan. It is necessary to combine nature conservation with reasonable economic utilization and tourism for protecting natural resources and maximizing its ecological,social and economic benefits.

  15. Synthesis of branched naphthoquinones from castor oil

    Directory of Open Access Journals (Sweden)

    Adriano Olímpio da Silva

    2012-06-01

    Full Text Available The naphthoquinones are cyclic aromatic α,β-dienonas with a basic framework derived from naphthalene. They are also found in many higher plants, algae, fungi and as the product of the  metabolism  of some  bacteria  having large biologica activity described in the literature such as antibacterial, anti-inflammatory, antitumor, anticancer and trypanocidal [1-3]. Castor oil is an abundant raw material in Brazil of great versatility and, it is present in biodiesel production, surfactants, cosmetics and others. Considering the importance of naphthoquinones and, the availability of the ricinoleic acid from castor oil, the aim of this study was the preparation of new branched naphthoquinones in order to test their trypanocidal activity. Castor oil was submitted to saponification with sodium hydroxide, ethanol and water under reflux for 6 h. We then carried out an acid hydrolysis with hydrochloric acid and the formed ricinoleic acid was extracted with ethyl acetate. Following, through Kochi-Anderson addition reaction it was performed the alkylation of a naphthoquinone 1 and 2, using ammonium persulfate, silver nitrate, acetonitrile and water, under heating at 70-80 ° C during 3 h, to give the branched naphthoquinones 4 and 5 (scheme 1. The naphthoquinone 3 will be similarly submitted to this procedure. The naphthoquinones 4 and 5 were purified by column chromatography on sílica gel using hexane as the eluent. The compounds were characterized by mass spectrometry and 1H and 13CNMR spectroscopy.

  16. Branching dynamics of viral information spreading

    Science.gov (United States)

    Iribarren, José Luis; Moro, Esteban

    2011-10-01

    Despite its importance for rumors or innovations propagation, peer-to-peer collaboration, social networking, or marketing, the dynamics of information spreading is not well understood. Since the diffusion depends on the heterogeneous patterns of human behavior and is driven by the participants’ decisions, its propagation dynamics shows surprising properties not explained by traditional epidemic or contagion models. Here we present a detailed analysis of our study of real viral marketing campaigns where tracking the propagation of a controlled message allowed us to analyze the structure and dynamics of a diffusion graph involving over 31 000 individuals. We found that information spreading displays a non-Markovian branching dynamics that can be modeled by a two-step Bellman-Harris branching process that generalizes the static models known in the literature and incorporates the high variability of human behavior. It explains accurately all the features of information propagation under the “tipping point” and can be used for prediction and management of viral information spreading processes.

  17. Cravity modulation of the moss Tortula modica branching

    Science.gov (United States)

    Khorkavtsiv, Yaroslava; Kit, Nadja

    Among various abiotic factors the sensor system of plants constantly perceives light and gravitation impulses and reacts on their action by photo- and gravitropisms. Tropisms play fundamental part in ontogenesis and determination of plant forms. Essentially important question is how light initiating phototropic bending modulates gravitropism. In contrast to flower plants, red light is phototropically active for mosses, and phytochromic system controls initiation of apical growth, branching and photomorphogenesis of mosses. The aim of this investigation was to analyse cell branching of protonemata Tortula modica Zander depending on the direction of light and gravitation vector. The influence of light and gravitation on the form of protonemal turf T. modica, branching and the angle of lateral branches relative to axis of mother cell growth has been investigated. As moss protonemata is not branched in the darkness, light is necessary for branching activation. Minimally low intensity of the red light (0.2 mmol (.) m (-2) ({) .}sec (-1) ) induced branching without visual display of phototropic growth. It has been established that unidirectional action of light and gravitation intensifies branching, and, on the contrary, perpendicularly oriented vectors of factors weaken branches formation. Besides, parallel oriented vectors initiated branching from both cell sides, but oppositely directed vectors initiated branching only from one side. Clinostate rotation the change of the vector gravity and causes uniform cell branching, hence, light and gravitation mutually influence the branching system form of the protonemata cell. It has been shown that the angle of lateral branches in darkness does not depend on the direction of light and gravitation action. After lighting the local growth of the cell wall took place mainly under the angle 90 (o) to the axes of mother cell growth. Then the angle gradually decreased and in 3-4 cell divisions the lateral branch grew under the angle

  18. Mapping and Quantification of Vascular Branching in Plants, Animals and Humans by VESGEN Software

    Science.gov (United States)

    Parsons-Wingerter, P. A.; Vickerman, M. B.; Keith, P. A.

    2010-01-01

    Humans face daunting challenges in the successful exploration and colonization of space, including adverse alterations in gravity and radiation. The Earth-determined biology of plants, animals and humans is significantly modified in such extraterrestrial environments. One physiological requirement shared by larger plants and animals with humans is a complex, highly branching vascular system that is dynamically responsive to cellular metabolism, immunological protection and specialized cellular/tissue function. VESsel GENeration (VESGEN) Analysis has been developed as a mature beta version, pre-release research software for mapping and quantification of the fractal-based complexity of vascular branching. Alterations in vascular branching pattern can provide informative read-outs of altered vascular regulation. Originally developed for biomedical applications in angiogenesis, VESGEN 2D has provided novel insights into the cytokine, transgenic and therapeutic regulation of angiogenesis, lymphangiogenesis and other microvascular remodeling phenomena. Vascular trees, networks and tree-network composites are mapped and quantified. Applications include disease progression from clinical ophthalmic images of the human retina; experimental regulation of vascular remodeling in the mouse retina; avian and mouse coronary vasculature, and other experimental models in vivo. We envision that altered branching in the leaves of plants studied on ISS such as Arabidopsis thaliana cans also be analyzed.

  19. Morphological description of collateral branches from the abdominal aorta of lesser anteater (Tamandua tetradactyla

    Directory of Open Access Journals (Sweden)

    Breno Costa Macedo

    2013-03-01

    Full Text Available Tamandua tetradactyla, Xenarthra, is a native species from South America which, due to the few number of studies on its biology, still has many unknown aspects in its morphology. Taking into account the importance of morphological data for various studies, this paper aimed to elucidate the branching of the abdominal aorta in this species to foster the development of further studies. To do this, 4 specimens were used, 2 male and 2 female, all young, from the Bauxite Mine – Paragominas, Para, Brazil, donated after death due to running over to the Animal Morphology Research Laboratory (LaPMA of Universidade Federal Rural da Amazonia (UFRA. The arterial system was filled with contrasted latex and the animals were fixed in a formaldehyde solution (10%, and then dissected, in order to evidence the abdominal aorta and its collateral branches. The parietal branches consisted of 1 pair of caudal phrenic arteries, 2 pairs of intercostal arteries, and 3 pairs of lumbar arteries. Among the visceral branches, stood out: celiac artery; cranial mesenteric artery; adrenal arteries; renal arteries; caudal mesenteric artery; and external, internal, and median sacral iliac arteries, formed from the final portion of the abdominal aorta. Testicular and ovarian arteries originated from the renal arteries, differing from that described in various species.

  20. Qualitative and quantitative analysis of branches in dextran using high-performance anion exchange chromatography coupled to quadrupole time-of-flight mass spectrometry.

    Science.gov (United States)

    Yi, Lin; Ouyang, Yilan; Sun, Xue; Xu, Naiyu; Linhardt, Robert J; Zhang, Zhenqing

    2015-12-01

    Dextran, a family of natural polysaccharides, consists of an α (1→6) linked-glucose main (backbone) chain having a number of branches. The determination of the types and the quantities of branches in dextran is important in understanding its various biological roles. In this study, a hyphenated method using high-performance anion exchange chromatography (HPAEC) in parallel with pulsed amperometric detection (PAD) and mass spectrometry (MS) was applied to qualitative and quantitative analysis of dextran branches. A rotary cation-exchange cartridge array desalter was used for removal of salt from the HPAEC eluent making it MS compatible. MS and MS/MS were used to provide structural information on the enzymatically prepared dextran oligosaccharides. PAD provides quantitative data on the ratio of enzyme-resistant, branched dextran oligosaccharides. Both the types and degree of branching found in a variety of dextrans could be simultaneously determined online using this method.

  1. The Genome Atlas Resource

    DEFF Research Database (Denmark)

    Azam Qureshi, Matloob; Rotenberg, Eva; Stærfeldt, Hans Henrik;

    2010-01-01

    Abstract. The Genome Atlas is a resource for addressing the challenges of synchronising prokaryotic genomic sequence data from multiple public repositories. This resource can integrate bioinformatic analyses in various data format and quality. Existing open source tools have been used together...... with scripts and algorithms developed in a variety of programming languages at the Centre for Biological Sequence Analysis in order to create a three-tier software application for genome analysis. The results are made available via a web interface developed in Java, PHP and Perl CGI. User...

  2. Modeling of branching density and branching distribution in low-density polyethylene polymerization

    NARCIS (Netherlands)

    D.M. Kim; P.D. Iedema

    2008-01-01

    Low-density polyethylene (ldPE) is a general purpose polymer with various applications. By this reason, many publications can be found on the ldPE polymerization modeling. However, scission reaction and branching distribution are only recently considered in the modeling studies due to difficulties i

  3. POISSON REPRESENTATIONS OF BRANCHING MARKOV AND MEASURE-VALUED BRANCHING PROCESSES

    NARCIS (Netherlands)

    Kurtz, Thomas G.; Rodrigues, Eliane R.

    2011-01-01

    Representations of branching Markov processes and their measure-valued limits in terms of countable systems of particles are constructed for models with spatially varying birth and death rates. Each particle has a location and a "level," but unlike earlier constructions, the levels change with time.

  4. Mesozooplankton size data from the fjord branch Kapisigdlit located in the Godthaabsfjord system, West Greenland

    DEFF Research Database (Denmark)

    2013-01-01

    branch, in the middle of a shallower inner creek . St. 1-4 was covering deeper parts of the fjord, and St. 5 was located on the slope leading up to the shallow inner creek. Mesozooplankton was sampled by vertical net tows using a Hydrobios Multinet (type Mini) equipped with a flow meter and 50 µm mesh......Sampling was conducted from March 24 to August 5 2010, in the fjord branch Kapisigdlit located in the inner part of the Godthåbsfjord system, West Greenland. The vessel "Lille Masik" was used during all cruises except on June 17-18 where sampling was done from RV Dana (National Institute...... for Aquatic Resources, Denmark). A total of 15 cruises (of 1-2 days duration) 7-10 days apart was carried out along a transect composed of 6 stations (St.), spanning the length of the 26 km long fjord branch. St. 1 was located at the mouth of the fjord branch and St. 6 was located at the end of the fjord...

  5. Mesozooplankton abundance data from the fjord branch Kapisigdlit located in the Godthaabsfjord system, West Greenland, 2010

    DEFF Research Database (Denmark)

    2013-01-01

    branch, in the middle of a shallower inner creek . St. 1-4 was covering deeper parts of the fjord, and St. 5 was located on the slope leading up to the shallow inner creek. Mesozooplankton was sampled by vertical net tows using a Hydrobios Multinet (type Mini) equipped with a flow meter and 50 µm mesh......Sampling was conducted from March 24 to August 5 2010, in the fjord branch Kapisigdlit located in the inner part of the Godthåbsfjord system, West Greenland. The vessel "Lille Masik" was used during all cruises except on June 17-18 where sampling was done from RV Dana (National Institute...... for Aquatic Resources, Denmark). A total of 15 cruises (of 1-2 days duration) 7-10 days apart was carried out along a transect composed of 6 stations (St.), spanning the length of the 26 km long fjord branch. St. 1 was located at the mouth of the fjord branch and St. 6 was located at the end of the fjord...

  6. Managing biological diversity

    Science.gov (United States)

    Samson, Fred B.; Knopf, Fritz L.

    1993-01-01

    Biological diversity is the variety of life and accompanying ecological processes (Off. Technol. Assess. 1987, Wilcove and Samson 1987, Keystone 1991). Conservation of biological diversity is a major environmental issue (Wilson 1988, Counc. Environ. Quality 1991). The health and future of the earth's ecological systems (Lubchenco et al. 1991), global climate change (Botkin 1990), and an ever-increasing rate in loss of species, communities, and ecological systems (Myers 1990) are among issues drawing biological diversity to the mainstream of conservation worldwide (Int. Union Conserv. Nat. and Nat. Resour. [IUCN] et al. 1991). The legal mandate for conserving biological diversity is now in place (Carlson 1988, Doremus 1991). More than 19 federal laws govern the use of biological resources in the United States (Rein 1991). The proposed National Biological Diversity Conservation and Environmental Research Act (H.R. 585 and S.58) notes the need for a national biological diversity policy, would create a national center for biological diversity research, and recommends a federal interagency strategy for ecosystem conservation. There are, however, hard choices ahead for the conservation of biological diversity, and biologists are grappling with how to set priorities in research and management (Roberts 1988). We sense disillusion among field biologists and managers relative to how to operationally approach the seemingly overwhelming charge of conserving biological diversity. Biologists also need to respond to critics like Hunt (1991) who suggest a tree farm has more biological diversity than an equal area of old-growth forest. At present, science has played only a minor role in the conservation of biological diversity (Weston 1992) with no unified approach available to evaluate strategies and programs that address the quality and quantity of biological diversity (Murphy 1990, Erwin 1992). Although actions to conserve biological diversity need to be clearly defined by

  7. Additional chain-branching pathways in the low-temperature oxidation of branched alkanes

    KAUST Repository

    Wang, Zhandong

    2015-12-31

    Chain-branching reactions represent a general motif in chemistry, encountered in atmospheric chemistry, combustion, polymerization, and photochemistry; the nature and amount of radicals generated by chain-branching are decisive for the reaction progress, its energy signature, and the time towards its completion. In this study, experimental evidence for two new types of chain-branching reactions is presented, based upon detection of highly oxidized multifunctional molecules (HOM) formed during the gas-phase low-temperature oxidation of a branched alkane under conditions relevant to combustion. The oxidation of 2,5-dimethylhexane (DMH) in a jet-stirred reactor (JSR) was studied using synchrotron vacuum ultra-violet photoionization molecular beam mass spectrometry (SVUV-PI-MBMS). Specifically, species with four and five oxygen atoms were probed, having molecular formulas of C8H14O4 (e.g., diketo-hydroperoxide/keto-hydroperoxy cyclic ether) and C8H16O5 (e.g., keto-dihydroperoxide/dihydroperoxy cyclic ether), respectively. The formation of C8H16O5 species involves alternative isomerization of OOQOOH radicals via intramolecular H-atom migration, followed by third O2 addition, intramolecular isomerization, and OH release; C8H14O4 species are proposed to result from subsequent reactions of C8H16O5 species. The mechanistic pathways involving these species are related to those proposed as a source of low-volatility highly oxygenated species in Earth\\'s troposphere. At the higher temperatures relevant to auto-ignition, they can result in a net increase of hydroxyl radical production, so these are additional radical chain-branching pathways for ignition. The results presented herein extend the conceptual basis of reaction mechanisms used to predict the reaction behavior of ignition, and have implications on atmospheric gas-phase chemistry and the oxidative stability of organic substances. © 2015 The Combustion Institute.

  8. 乌头属药物资源的化学和生物学研究进展%Recent advances in the chemical and biological studies of Aconitum pharmaceutical resources

    Institute of Scientific and Technical Information of China (English)

    郝大程; 顾晓洁; 肖培根; 许利嘉; 彭勇

    2013-01-01

    毛莨科乌头属药用植物含有二萜生物碱、多糖、黄酮类等药物活性成份,促进了对其化学分类学、分子分类学和药理学的研究.作为药用植物亲缘学的继续深入研究,本文综述乌头属的植物化学、化学分类、分子生物学和系统发育等方面的近期进展及其与乌头药效和毒性的关联.近年在多种乌头植物中发现了更多二萜生物碱,以C19:Ⅲ,aconitine类型最多.综述了近年发现的乌头生物碱和提取物,以及乌头多糖和其它成分的生物活性.国产乌头亚属中乌头组基于形态学的11系分类未得到化学分类和分子系统发育研究的支持.基于细胞核和叶绿体DNA序列的分子系统树将形态极相近的9系分为两群,一为甘青乌头系,圆叶乌头系,保山乌头系和短柄乌头系;另一为乌头系,兴安乌头系,显柱乌头系,蔓乌头系和准噶尔乌头系,化学分类数据支持此分群.为了乌头资源的可持续利用和发现高效低毒的新化合物,有必要将近年涌现的新技术用于乌头研究.系统生物学和组学技术将在促进乌头生物活性化合物研究中发挥关键作用.%Many herbal medicines have so far been utilized for the treatment of various ailments since the beginning of Chinese civilization.Aconitum is a botanical source for various pharmaceutically active components,which has been commonly used in traditional Chinese medicine for thousands of years.Increasing interest in Aconitum pharmaceutical resources has led to further discoveries of diterpenoid alkaloids,polysaccharides,flavonoids and many other compounds in various Aconitum species,and to investigations on their chemotaxonomy,molecular phylogeny and pharmacology.In continuation with our studies on Aconitum pharmacophylogeny,here we review the phytochemistry,chemotaxonomy,molecular biology and phylogeny of Aconitum and their relevance to therapeutic efficacy and toxicity.An exhaustive literature survey is

  9. ANALYSIS OF BRANCHING DISTRIBUTION IN POLYETHYLENES BY DIFFERENTIAL SCANNING CALORIMETRY

    Institute of Scientific and Technical Information of China (English)

    Robert Shanks; Fei Chen; Gandara Amarasinghe

    2003-01-01

    Short chain branching has been characterized using thermal fractionation, a stepwise isothermal crystallization technique, followed by a melting analysis scan using differential scanning calorimetry. Short chain branching distribution was also characterized by a continuous slow cooling crystallization, followed by a melting analysis scan. Four different polyethylenes were studied: Ziegler-Natta gas phase, Ziegler-Natta solution, metallocene, constrained-geometry single site catalyzed polyethylenes. The branching distribution was calculated from a calibration of branch content with melting temperature. The lamellar thickness was calculated based on the thermodynamic melting temperature of each polyethylene and the surface free energy of the crystal face. The branching distribution and lamellar thickness distribution were used to calculate weight average branch content, mean lamellar thickness, and a branch dispersity index. The results for the branch content were in good agreement with the known comonomer content of the polyethylenes. A limitation was that high branch content polyethylenes did not reach their potential crystallization at ambient temperatures. Cooling to sub-ambient was necessary to equilibrate the crystallization, but melting temperature versus branch content was not applicable after cooling to below ambient because the calibration data were not performed in this way.

  10. Quantification of branching in model three-arm star polyethylene

    KAUST Repository

    Ramachandran, Ramnath

    2012-01-24

    The versatility of a novel scaling approach in quantifying the structure of model well-defined 3-arm star polyethylene molecules is presented. Many commercial polyethylenes have long side branches, and the nature and quantity of these branches varies widely among the various forms. For instance, low-density polyethylene (LDPE) is typically a highly branched structure with broad distributions in branch content, branch lengths and branch generation (in hyperbranched structures). This makes it difficult to accurately quantify the structure and the inherent structure-property relationships. To overcome this drawback, model well-defined hydrogenated polybutadiene (HPB) structures have been synthesized via anionic polymerization and hydrogenation to serve as model analogues to long-chain branched polyethylene. In this article, model 3-arm star polyethylene molecules are quantified using the scaling approach. Along with the long-chain branch content in polyethylene, the approach also provides unique measurements of long-chain branch length and hyperbranch content. Such detailed description facilitates better understanding of the effect of branching on the physical properties of polyethylene. © 2012 American Chemical Society.

  11. Genetic toxicology: web resources.

    Science.gov (United States)

    Young, Robert R

    2002-04-25

    Genetic toxicology is the scientific discipline dealing with the effects of chemical, physical and biological agents on the heredity of living organisms. The Internet offers a wide range of online digital resources for the field of Genetic Toxicology. The history of genetic toxicology and electronic data collections are reviewed. Web-based resources at US National Library of Medicine (NLM), including MEDLINE, PUBMED, Gateway, Entrez, and TOXNET, are discussed. Search strategies and Medical Subject Headings (MeSH) are reviewed in the context of genetic toxicology. The TOXNET group of databases are discussed with emphasis on those databases with genetic toxicology content including GENE-TOX, TOXLINE, Hazardous Substances Data Bank, Integrated Risk Information System, and Chemical Carcinogenesis Research Information System. Location of chemical information including chemical structure and linkage to health and regulatory information using CHEMIDPLUS at NLM and other databases is reviewed. Various government agencies have active genetic toxicology research programs or use genetic toxicology data to assist fulfilling the agency's mission. Online resources at the US Food and Drug Administration (FDA), the US Environmental Protection Agency (EPA), the National Institutes of Environmental Health Sciences, and the National Toxicology Program (NTP) are outlined. Much of the genetic toxicology for pharmaceuticals, industrial chemicals and pesticides that is performed in the world is regulatory-driven. Regulatory web resources are presented for the laws mandating testing, guidelines on study design, Good Laboratory Practice (GLP) regulations, and requirements for electronic data collection and reporting. The Internet provides a range of other supporting resources to the field of genetic toxicology. The web links for key professional societies and journals in genetic toxicology are listed. Distance education, educational media resources, and job placement services are also

  12. Differential Activity of Striga hermonthica Seed Germination Stimulants and Gigaspora rosea Hyphal Branching Factors in Rice and Their Contribution to Underground Communication

    OpenAIRE

    Cardoso, C.; Charnikhova, T.; M. Jamil; Delaux, P.M.; Verstappen, F.W.A.; M. Amini; Lauressergues, D.; Ruyter-Spira, C. P.; Bouwmeester, H.J.

    2014-01-01

    Strigolactones (SLs) trigger germination of parasitic plant seeds and hyphal branching of symbiotic arbuscular mycorrhizal (AM) fungi. There is extensive structural variation in SLs and plants usually produce blends of different SLs. The structural variation among natural SLs has been shown to impact their biological activity as hyphal branching and parasitic plant seed germination stimulants. In this study, rice root exudates were fractioned by HPLC. The resulting fractions were analyzed by ...

  13. A Comparison of Fresh Frozen vs. Formalin-Fixed, Paraffin-Embedded Specimens of Canine Mammary Tumors via Branched-DNA Assay

    OpenAIRE

    Florenza Lüder Ripoli; Annika Mohr; Susanne Conradine Hammer; Saskia Willenbrock; Marion Hewicker-Trautwein; Silvia Hennecke; Hugo Murua Escobar; Ingo Nolte

    2016-01-01

    Mammary neoplasms are the tumors most affecting female dogs and women. Formalin-fixed, paraffin-embedded (FFPE) tissues are an invaluable source of archived biological material. Fresh frozen (FF) tissue is considered ideal for gene expression analysis. However, strategies based on FFPE material offer several advantages. Branched-DNA assays permit a reliable and fast workflow when analyzing gene expression. The aim of this study was to assess the comparability of the branched-DNA assay when an...

  14. 云南及周边地区少数民族对农业生物资源的保护与利用%Conservation and Utilization on Biological Resources of Agriculture of Minority Nationality in Yunnan Province and Its Peripheral Area

    Institute of Scientific and Technical Information of China (English)

    郑殿升; 游承俐; 高爱农; 李立会; 刘旭

    2012-01-01

    The project of " investigation of biological resources of agriculture in Yunnan province and its peripheral area" belongs to National Basic Task Program of the Ministry of Science and Technology. Yunnan and its peripheral area are the concentrative areas inhabited by minority nationality people where the biological diversity of agriculture is quite abundance. However,the vicissitude is happening that minority cultures and biological resources of agriculture are disappearing gradually along with economic development and infiltration of external cultures. In order to conserve and develop traditional culture and biological resource of agriculture in the minority area, forties counties and ten minority nationalities were investigated and all tasks were completed as the project requires. The authors introduced conservation and utilization on biological resources of agriculture of minority nationality in Yunnan province and its peripheral area, in which the aim was focused on providing basic information and scientific evidences for conservation and development of traditional culture of minority, and constituting the conservation policy of biological resources and scientific researches.%“云南及周边地区生物资源调查”项目属于国家科技部基础性工作专项.云南及周边地区是我国少数民族聚集区,农业生物多样性十分丰富.然而,近些年来随着经济发展,外来文化的渗透,该地区正经历着较大的变迁,少数民族文化和农业生物资源正在逐步消失[1].为了保护和发扬少数民族的传统文化和农业生物资源,对该地区的41个县和10个民族进行了系统调查.本次调查全面完成了各项任务和考核指标.本文仅介绍云南及周边地区少数民族对农业生物资源的保护和利用情况,旨在为国家保护和发扬少数民族传统文化,制定生物资源保护政策和科学研究提供基础信息和科学依据.

  15. Gauge Theories on the Coulomb branch

    CERN Document Server

    Schwarz, John H

    2014-01-01

    We construct the world-volume action of a probe D3-brane in $AdS_5 \\times S^5$ with $N$ units of flux. It has the field content, symmetries, and dualities of the $U(1)$ factor of ${\\cal N} =4$ $U(N+1)$ super Yang--Mills theory, spontaneously broken to $U(N) \\times U(1)$ by being on the Coulomb branch, with the massive fields integrated out. This motivates the conjecture that it is the exact effective action, called a `highly effective action' (HEA). We construct an $SL(2,Z)$ multiplet of BPS soliton solutions of the D3-brane theory (the conjectured HEA) and show that it reproduces the electrically charged massive states that have been integrated out as well as magnetic monopoles and dyons. Their charges are uniformly spread on a spherical surface, called a `soliton bubble', which is interpreted as a phase boundary.

  16. Multimodal Distributions along the Horizontal Branch

    CERN Document Server

    Ferraro, F R; Pecci, F F; Dorman, B; Rood, R T; Ferraro, Francesco R.; Paltrinieri, Barbara; Pecci, Flavio Fusi; Dorman, Ben; Rood, Robert T.

    1997-01-01

    We report on HST/WFPC2 U,V and far-ultraviolet observations of two Galactic Globular Clusters (GGCs), NGC 6205 = M13 and NGC 6093 = M80. Both of these clusters have horizontal-branch (HB) tails that extend to the helium-burning main sequence, with the hottest stars reaching theoretical effective temperatures above 35,000 K. In both clusters, groups of stars are found to be separated by narrow gaps along the blue HB sequence. These gaps appear at similar locations in the color-magnitude diagrams of the two clusters. While stochastic effects may give rise to variations in the color distribution along the HB, the coincidence of gaps in different clusters effectively rules this out as the primary cause. The comparison among the clusters strongly suggests that there are separate physical processes operating during the earlier red-giant phase of evolution to produce mass loss.

  17. Unquenched flavor on the Higgs branch

    CERN Document Server

    Faedo, Anton F; Pantelidou, Christiana; Tarrio, Javier

    2016-01-01

    We construct the gravity duals of the Higgs branches of three-dimensional (four-dimensional) super Yang-Mills theories coupled to $N_\\textrm{f}$ quark flavors. The effect of the quarks on the color degrees of freedom is included, and corresponds on the gravity side to the backreaction of $N_\\textrm{f}$ flavor D6-branes (D7-branes) on the background of $N_\\textrm{c}$ color D2-branes (D3-branes). The Higgsing of the gauge group arises from the dissolution of some color branes inside the flavor branes. The dissolved color branes are represented by non-Abelian instantons whose backreaction is also included. The result is a cascading-like solution in which the effective number of color branes varies along the holographic direction. In the three-dimensional case the solution may include an arbitrary number of quasi-conformal (walking) regions.

  18. Branching process in a stochastic extremal model

    Science.gov (United States)

    Manna, S. S.

    2009-08-01

    We considered a stochastic version of the Bak-Sneppen model (SBSM) of ecological evolution where the number M of sites mutated in a mutation event is restricted to only two. Here the mutation zone consists of only one site and this site is randomly selected from the neighboring sites at every mutation event in an annealed fashion. The critical behavior of the SBSM is found to be the same as the BS model in dimensions d=1 and 2. However on the scale-free graphs the critical fitness value is nonzero even in the thermodynamic limit but the critical behavior is mean-field like. Finally ⟨M⟩ has been made even smaller than two by probabilistically updating the mutation zone, which also shows the original BS model behavior. We conjecture that a SBSM on any arbitrary graph with any small branching factor greater than unity will lead to a self-organized critical state.

  19. Blue Horizontal Branch Stars in M92

    CERN Document Server

    Cohen, J G

    1997-01-01

    We have analyzed high dispersion and high precision spectra of 5 blue horizontal branch stars in the globular cluster M92 to establish that the projected rotational velocity for these stars ranges from 15 to 40 \\kms. This is larger than that expected based on the rotation of their main sequence progenitors, the spin down of rotation with age, and the conservation of angular momentum. Possible explanations include a rapidly rotating stellar core. An abundance analysis of these spectra of these blue HB stars in M92 yields the same results as have been obtained from the giants in this cluster. There is a hint of a trend of higher abundance as the projected surface rotational velocity increases, which could be chance and requires confirmation.

  20. Simple statistical model for branched aggregates

    DEFF Research Database (Denmark)

    Lemarchand, Claire; Hansen, Jesper Schmidt

    2015-01-01

    We propose a statistical model that can reproduce the size distribution of any branched aggregate, including amylopectin, dendrimers, molecular clusters of monoalcohols, and asphaltene nanoaggregates. It is based on the conditional probability for one molecule to form a new bond with a molecule......, given that it already has bonds with others. The model is applied here to asphaltene nanoaggregates observed in molecular dynamics simulations of Cooee bitumen. The variation with temperature of the probabilities deduced from this model is discussed in terms of statistical mechanics arguments....... The relevance of the statistical model in the case of asphaltene nanoaggregates is checked by comparing the predicted value of the probability for one molecule to have exactly i bonds with the same probability directly measured in the molecular dynamics simulations. The agreement is satisfactory...

  1. Basic Sciences Branch annual report, FY 1990

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1989, through September 30, 1990. Six technical sections of the report cover these main areas of NREL's in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Solid-State Spectroscopy. Each section of the report was written by the group leader principally in charge of the work. The task in each case was to explain the purpose and major accomplishments of the work in the context of the US Department of Energy's National Photovoltaic Research Program plans.

  2. Basic Sciences Branch annual report, FY 1990

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1989, through September 30, 1990. Six technical sections of the report cover these main areas of NREL`s in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Solid-State Spectroscopy. Each section of the report was written by the group leader principally in charge of the work. The task in each case was to explain the purpose and major accomplishments of the work in the context of the US Department of Energy`s National Photovoltaic Research Program plans.

  3. Cold holographic matter in the Higgs branch

    Science.gov (United States)

    Itsios, Georgios; Jokela, Niko; Ramallo, Alfonso V.

    2015-07-01

    We study collective excitations of cold (2 + 1)-dimensional fundamental matter living on a defect of the four-dimensional N = 4 super Yang-Mills theory in the Higgs branch. This system is realized holographically as a D3-D5 brane intersection, in which the D5-brane is treated as a probe with a non-zero gauge flux across the internal part of its worldvolume. We study the holographic zero sound mode in the collisionless regime at low temperature and find a simple analytic result for its dispersion relation. We also find the diffusion constant of the system in the hydrodynamic regime at higher temperature. In both cases we study the dependence on the flux parameter which determines the amount of Higgs symmetry breaking. We also discuss the anyonization of this construction.

  4. Cold holographic matter in the Higgs branch

    CERN Document Server

    Itsios, Georgios; Ramallo, Alfonso V

    2015-01-01

    We study collective excitations of cold (2+1)-dimensional fundamental matter living on a defect of the four-dimensional N=4 super Yang-Mills theory in the Higgs branch. This system is realized holographically as a D3-D5 brane intersection, in which the D5-brane is treated as a probe with a non-zero gauge flux across the internal part of its worldvolume. We study the holographic zero sound mode in the collisionless regime at low temperature and find a simple analytic result for its dispersion relation. We also find the diffusion constant of the system in the hydrodynamic regime at higher temperature. In both cases we study the dependence on the flux parameter which determines the amount of Higgs symmetry breaking. We also discuss the anyonization of this construction.

  5. Cold holographic matter in the Higgs branch

    Directory of Open Access Journals (Sweden)

    Georgios Itsios

    2015-07-01

    Full Text Available We study collective excitations of cold (2+1-dimensional fundamental matter living on a defect of the four-dimensional N=4 super Yang–Mills theory in the Higgs branch. This system is realized holographically as a D3–D5 brane intersection, in which the D5-brane is treated as a probe with a non-zero gauge flux across the internal part of its worldvolume. We study the holographic zero sound mode in the collisionless regime at low temperature and find a simple analytic result for its dispersion relation. We also find the diffusion constant of the system in the hydrodynamic regime at higher temperature. In both cases we study the dependence on the flux parameter which determines the amount of Higgs symmetry breaking. We also discuss the anyonization of this construction.

  6. Planets around Extreme Horizontal Branch Stars

    CERN Document Server

    Bear, E

    2011-01-01

    We review three main results of our recent study: We show that a proper treatment of the tidal interaction prior to the onset of the common envelope (CE) leads to an enhance mass loss. This might increase the survivability of planets and brown dwarfs that enter a CE phase. From the distribution of planets around main sequence stars, we conclude that around many sdB/sdO stars more than one planet might be present. One of these might have a close orbit and the others at about orbital periods of years or more. We show that the intense ionizing flux of the extreme horizontal branch star might evaporate large quantities of a very close surviving substellar object. Balmer emission lines from the evaporated gas can be detected via their Doppler shifts.

  7. Planets around extreme horizontal branch stars

    CERN Document Server

    Bear, Ealeal

    2010-01-01

    We review three main results of our recent study: * We show that a proper treatment of the tidal interaction prior to the onset of the common envelope (CE) leads to an enhance mass loss. This might increase the survivability of planets and brown dwarfs that enter a CE phase. * From the distribution of planets around main sequence stars, we conclude that around many sdB/sdO stars more than one planet might be present. One of these might have a close orbit and the others at about orbital periods of years or more. * We show that the intense ionizing flux of the extreme horizontal branch star might evaporate large quantities of a very close surviving substellar object. Balmer emission lines from the evaporated gas can be detected via their Doppler shifts.

  8. Flight Dynamics Analysis Branch 2005 Technical Highlights

    Science.gov (United States)

    2005-01-01

    This report summarizes the major activities and accomplishments carried out by the Flight Dynamics Analysis Branch (FDAB), Code 595, in support of flight projects and technology development initiatives in Fiscal Year (FY) 2005. The report is intended to serve as a summary of the type of support carried out by the FDAB, as well as a concise reference of key accomplishments and mission experience derived from the various mission support roles. The primary focus of the FDAB is to provide expertise in the disciplines of flight dynamics including spacecraft navigation (autonomous and ground based); spacecraft trajectory design and maneuver planning; attitude analysis; attitude determination and sensor calibration; and attitude control subsystem (ACS) analysis and design. The FDAB currently provides support for missions and technology development projects involving NASA, other government agencies, academia, and private industry.

  9. Unscrambling Key Features of TED as Open Educational Resources

    Institute of Scientific and Technical Information of China (English)

    汪静静; QIU; Cai-zhen

    2015-01-01

    TED is a particularly thriving branch in the campaign of Open Educational Resources,leading future educational revolution.What makes TED distinguished from other agents of open educational resources is worth studying.This paper studies key features of TED talks that help to explain why TED talks are so appealing,provide deeper look at TED and explore its value.

  10. Fourth annual Walker Branch Watershed research symposium: Program and abstracts

    International Nuclear Information System (INIS)

    The methods and concepts of watershed research, originally applied in an experimental or monitoring mode to relatively small catchments, are increasingly being used at larger scales and for specific applied problems. Research at Oak Ridge National Laboratory, the Tennessee Valley Authority, the US Forest Service, and other agencies and institutions participating in this symposium reflects research over a broad range of spatial scales that is being integrated through large-scale experiments along with computer modeling and graphical interfaces. These research projects address the basic atmospheric, geophysical, biogeochemical, and biological processes that regulate the responses of forested ecosystems to natural environmental variation and anthropogenic stresses. This symposium highlights the use of large-scale ecosystem experiments to address environmental issues of global concern. These experiments provide the only effective way to test models of ecosystem response that are based on the current state of knowledge of hydrology, biogeochemistry, plant physiology, and other ecosystem processes. Major environmental problems that are being addressed include acidic deposition and nitrogen loading (Bear Brook Watershed, Maine; and the Girdsjoen Covered Catchment, Sweden); climate warming (Soil Warming Experiment, Maine); and altered rainfall amounts (Savannah River Loblolly Pine Soil Water Manipulation and the Walker Branch Watershed Throughfall Displacement Experiment)

  11. Branch xylem density variations across Amazonia

    Directory of Open Access Journals (Sweden)

    S. Patiño

    2008-05-01

    Full Text Available Measurements of branch xylem density, Dx, were made for 1466 trees representing 503 species, sampled from 80 sites across the Amazon basin. Measured values ranged from 240 kg m−3 for a Brosimum parinarioides from Tapajos in West Pará, Brazil to 1130 kg m−3 for an Aiouea sp. from Caxiuana, Central Pará, Brazil. Analysis of variance showed significant differences in average Dx across the sample plots as well as significant differences between families, genera and species. A partitioning of the total variance in the dataset showed that geographic location and plot accounted for 33% of the variation with species identity accounting for an additional 27%; the remaining "residual" 40% of the variance accounted for by tree to tree (within species variation. Variations in plot means, were, however, hardly accountable at all by differences in species composition. Rather, it would seem that variations of xylem density at plot level must be explained by the effects of soils and/or climate. This conclusion is supported by the observation that the xylem density of the more widely distributed species varied systematically from plot to plot. Thus, as well as having a genetic component branch xylem density is a plastic trait that, for any given species, varies according to where the tree is growing and in a predictable manner. Exceptions to this general rule may be some pioneers belonging to Pourouma and Miconia and some species within the genera Brosimum, Rinorea and Trichillia which seem to be more constrained in terms of this plasticity than most species sampled as part of this study.

  12. Resources and Operations Section

    International Nuclear Information System (INIS)

    Progress is reported on the data resources group with regard to numeric information support; IBP data center; and geoecology project. Systems ecology studies consisted of nonlinear analysis-time delays in a host-parasite model; dispersal of seeds by animals; three-dimensional computer graphics in ecology; spatial heterogeneity in ecosystems; and analysis of forest structure. Progress is also reported on the national inventory of biological monitoring programs; ecological sciences information center; and educational activities

  13. Command and Data Handling Branch Internship

    Science.gov (United States)

    Billings, Rachel Mae

    2016-01-01

    Modular Integrated Stackable Layers (MISL) is a computer system designed for simple, fast, and cost effective flexible reconfiguration in space environments such as the ISS and Orion projects for various uses. Existing applications include wireless and wired communications, data acquisition and instrumentation, and camera systems, and potential applications include bus protocol converters and subsystem control. MISL is based on Texas Instruments (TI)' MSP430 16-bit ultra-low-power microcontroller device. The purpose of my project was to integrate the MISL system with a liquid crystal display (LCD) touchscreen. The LCD, manufactured by Crystalfontz and part number CFAF320240F-035T-TS, is a 320 by 240 RGB resistive color screen including an optional carrier board. The vast majority of the project was done with Altium Designer, a tool for printed circuit board (PCB) schematic capture, 3D design, and FPGA (Field Programmable Gate Array) development. The new PCB was to allow the LCD to directly stack to the rest of MISL. Research was done with datasheets for the TI microcontroller and touchscreen display in order to meet desired hardware specifications. Documentation on prior MISL projects was also utilized. The initial step was to create a schematic for the LCD, power bus, and data bus connections between components. A layout was then designed with the required physical dimensions, routed traces and vias, power and ground planes, layer stacks, and other specified design rules such as plane clearance and hole size. Multiple consultation sessions were held with Hester Yim, the technical discipline lead for the Command and Data Handling Branch, and Christy Herring, the lead PCB layout designer in the Electronic Design and Manufacturing Branch in order to ensure proper configuration. At the moment, the PCB is awaiting revision by the latter-mentioned branch. Afterwards, the board will begin to undergo the manufacturing and testing process. Throughout the internship at

  14. Branched projective structures with quasi-Fuchsian holonomy

    CERN Document Server

    Calsamiglia, Gabriel; Francaviglia, Stefano

    2012-01-01

    We prove that if S is a closed compact surface of negative Euler characteristic, and if R is a quasi-Fuchsian representation in PSL(2,C), then the deformation space M(k,R) of branched projective structures on S with total branching order k and holonomy R is connected, as soon as k>0. Equivalently, two branched projective structures with the same quasi-Fuchsian holonomy and the same number of branch points are related by a movement of branch points. In particular grafting annuli are obtained by moving branch points. In the appendix we give an explicit atlas for the space M(k,R). It is shown to be a smooth complex manifold modeled on Hurwitz spaces.

  15. The Horizontal Branch of the Sculptor Dwarf galaxy

    CERN Document Server

    Salaris, Maurizio; Tolstoy, Eline; Fiorentino, Giuliana; Cassisi, Santi

    2013-01-01

    We have performed the first detailed simulation of the horizontal branch of the Sculptor dwarf spheroidal galaxy by means of synthetic modelling techniques,taking consistently into account the star formation history and metallicity evolution as determined from the main sequence and red giant branch spectroscopic observations. The only free parameter in the whole analysis is the integrated mass loss of red giant branch stars. This is the first time that synthetic horizontal branch models, consistent with the complex star formation history of a galaxy, are calculated and matched to the observations. We find that the metallicity range covered by the star formation history, as constrained by observations, plus a simple mass loss law, enable us to cover both the full magnitude and colour range of HB stars. In addition the number count distribution along the observed horizontal branch, can be also reproduced, provided that the red giant branch mass loss is mildly metallicity dependent, with a very small dispersion ...

  16. Is synthetic biology mechanical biology?

    Science.gov (United States)

    Holm, Sune

    2015-12-01

    A widespread and influential characterization of synthetic biology emphasizes that synthetic biology is the application of engineering principles to living systems. Furthermore, there is a strong tendency to express the engineering approach to organisms in terms of what seems to be an ontological claim: organisms are machines. In the paper I investigate the ontological and heuristic significance of the machine analogy in synthetic biology. I argue that the use of the machine analogy and the aim of producing rationally designed organisms does not necessarily imply a commitment to mechanical biology. The ideal of applying engineering principles to biology is best understood as expressing recognition of the machine-unlikeness of natural organisms and the limits of human cognition. The paper suggests an interpretation of the identification of organisms with machines in synthetic biology according to which it expresses a strategy for representing, understanding, and constructing living systems that are more machine-like than natural organisms.

  17. Biology Notes.

    Science.gov (United States)

    School Science Review, 1982

    1982-01-01

    Presents procedures, exercises, demonstrations, and information on a variety of biology topics including labeling systems, biological indicators of stream pollution, growth of lichens, reproductive capacity of bulbous buttercups, a straw balance to measure transpiration, interaction of fungi, osmosis, and nitrogen fixation and crop production. (DC)

  18. Deregulation of Bank Entry and Branching: Impact on Competition

    OpenAIRE

    Milo, Melanie S.

    2001-01-01

    This paper looks at public policy towards bank entry and branching in the Philippines and its impact on the sector’s structure, conduct and performance. In particular, it argues that regulatory restrictions on bank entry and branching have had adverse effects on competition, while the liberalization of these restrictions have led to a more competitive banking sector. The paper has two main sections. Section II presents the history of regulation of bank entry and branching in the Philippines. ...

  19. Persistence-Based Branch Misprediction Bounds for WCET Analysis

    DEFF Research Database (Denmark)

    Puffitsch, Wolfgang

    2015-01-01

    Branch prediction is an important feature of pipelined processors to achieve high performance. However, it can lead to overly pessimistic worst-case execution time (WCET) bounds when being modeled too conservatively. This paper presents bounds on the number of branch mispredictions for local dyna...... linear programming formulations of the WCET problem. An evaluation on a number of benchmarks shows that with these bounds, dynamic branch prediction does not necessarily lead to higher WCET bounds than static prediction schemes....

  20. Branch structure of corona discharge: experimental simulation and chemical properties

    International Nuclear Information System (INIS)

    The branch structure of corona discharge has been investigated via C2H2 corona discharge. Carbon filament with excellent branch structure is formed in the discharge. This carbon filament offers a direct mimic of the branch structure of corona discharge. It provides a very useful way to study on the average energy, physical and chemical characteristics of corona discharge. On this basis, the chemical property of corona discharge for methane conversion is discussed. (authors)

  1. Activities of the Development Branch. 1978-1981

    International Nuclear Information System (INIS)

    The activities carried out by the Development Branch from 1978 through 1981 are summarized. Subjects covered include: Metallurgy, Nuclear Fuels, Instrumentation and Control, Nuclear Reactors, as well as the various projects developed during this period and the administrative and technical activities of various groups belonging to this Branch. A list of publications by personnel of this Branch during the same period is also included. (C.A.K.)

  2. The Branching of Graphs in 2-d Quantum Gravity

    OpenAIRE

    Harris, M. G.

    1996-01-01

    The branching ratio is calculated for three different models of 2d gravity, using dynamical planar phi-cubed graphs. These models are pure gravity, the D=-2 Gaussian model coupled to gravity and the single spin Ising model coupled to gravity. The ratio gives a measure of how branched the graphs dominating the partition function are. Hence it can be used to estimate the location of the branched polymer phase for the multiple Ising model coupled to 2d gravity.

  3. Human vagus nerve branching in the cervical region.

    Directory of Open Access Journals (Sweden)

    Niels Hammer

    Full Text Available Vagus nerve stimulation is increasingly applied to treat epilepsy, psychiatric conditions and potentially chronic heart failure. After implanting vagus nerve electrodes to the cervical vagus nerve, side effects such as voice alterations and dyspnea or missing therapeutic effects are observed at different frequencies. Cervical vagus nerve branching might partly be responsible for these effects. However, vagus nerve branching has not yet been described in the context of vagus nerve stimulation.Branching of the cervical vagus nerve was investigated macroscopically in 35 body donors (66 cervical sides in the carotid sheath. After X-ray imaging for determining the vertebral levels of cervical vagus nerve branching, samples were removed to confirm histologically the nerve and to calculate cervical vagus nerve diameters and cross-sections.Cervical vagus nerve branching was observed in 29% of all cases (26% unilaterally, 3% bilaterally and proven histologically in all cases. Right-sided branching (22% was more common than left-sided branching (12% and occurred on the level of the fourth and fifth vertebra on the left and on the level of the second to fifth vertebra on the right side. Vagus nerves without branching were significantly larger than vagus nerves with branches, concerning their diameters (4.79 mm vs. 3.78 mm and cross-sections (7.24 mm2 vs. 5.28 mm2.Cervical vagus nerve branching is considerably more frequent than described previously. The side-dependent differences of vagus nerve branching may be linked to the asymmetric effects of the vagus nerve. Cervical vagus nerve branching should be taken into account when identifying main trunk of the vagus nerve for implanting electrodes to minimize potential side effects or lacking therapeutic benefits of vagus nerve stimulation.

  4. Pressure Change in Tee Branch Pipe in Oscillatory Flow

    OpenAIRE

    Daisuke Sakamoto; Chongho Youn; Toshiharu Kagawa

    2013-01-01

    The purpose of this paper is to contribute to the understanding of unsteady flow of branch pipes in pneumatic systems. Branch pipes are used in pneumatic pipe systems in various industrial fields. To predict the unsteady pressure changes in the pneumatic piping systems, it is necessary that the dynamic characteristics of branch pipes are at hand, in addition to the dynamic characteristic of single pipe. However, while so many studies are accumulated for a single pipe dynamics, few studies hav...

  5. Interaction forces between surfaces coated with highly branched polyelectrolytes

    OpenAIRE

    Pericet-Cámara, Ramón; Borkovec, Michal

    2007-01-01

    In this thesis, interactions between surfaces with adsorbed highly branched polyelectrolytes were studied with the colloidal probe technique. By studying the adsorption behavior of highly branched polyelectrolytes, the lateral distribution of the surface charge could be tuned by the appropriate adsorption conditions. By choosing different polyelecrtrolytes, namely highly branched poly(ethylenimine) (PEI) and poly(amido amine) (PAMAM) dendrimers, it was possible to investigate the forces betwe...

  6. Interaction forces between surfaces coated with highly branched polyelectrolytes

    OpenAIRE

    Pericet-Cámara, Ramón

    2006-01-01

    In this thesis, interactions between surfaces with adsorbed highly branched polyelectrolytes were studied with the colloidal probe technique. By studying the adsorption behavior of highly branched polyelectrolytes, the lateral distribution of the surface charge could be tuned by the appropriate adsorption conditions. By choosing different polyelecrtrolytes, namely highly branched poly(ethylenimine) (PEI) and poly(amido amine) (PAMAM) dendrimers, it was possible to investigate the forces betwe...

  7. Differential activity of Striga hermonthica seed germination stimulants and Gigaspora rosea hyphal branching factors in rice and their contribution to underground communication.

    Directory of Open Access Journals (Sweden)

    Catarina Cardoso

    Full Text Available Strigolactones (SLs trigger germination of parasitic plant seeds and hyphal branching of symbiotic arbuscular mycorrhizal (AM fungi. There is extensive structural variation in SLs and plants usually produce blends of different SLs. The structural variation among natural SLs has been shown to impact their biological activity as hyphal branching and parasitic plant seed germination stimulants. In this study, rice root exudates were fractioned by HPLC. The resulting fractions were analyzed by MRM-LC-MS to investigate the presence of SLs and tested using bioassays to assess their Striga hermonthica seed germination and Gigaspora rosea hyphal branching stimulatory activities. A substantial number of active fractions were revealed often with very different effect on seed germination and hyphal branching. Fractions containing (--orobanchol and ent-2'-epi-5-deoxystrigol contributed little to the induction of S. hermonthica seed germination but strongly stimulated AM fungal hyphal branching. Three SLs in one fraction, putative methoxy-5-deoxystrigol isomers, had moderate seed germination and hyphal branching inducing activity. Two fractions contained strong germination stimulants but displayed only modest hyphal branching activity. We provide evidence that these stimulants are likely SLs although no SL-representative masses could be detected using MRM-LC-MS. Our results show that seed germination and hyphal branching are induced to very different extents by the various SLs (or other stimulants present in rice root exudates. We propose that the development of rice varieties with different SL composition is a promising strategy to reduce parasitic plant infestation while maintaining symbiosis with AM fungi.

  8. Characteristic Variance Analysis on Morphology of Branches-leaves and Fruit Sense-organ of Prunus domestica L.Resources in Xinj iang%新疆欧洲李资源枝叶形态及果实感官特征差异分析

    Institute of Scientific and Technical Information of China (English)

    孙琪; 廖康; 耿文娟; 贾杨; 赵世荣; 彭晓莉

    2015-01-01

    In order to explore the difference of genetic diversity and genetic relationship between several types of Prunus domestica L.resources in Xinjiang,48 indicators on morphology of branches‐leaves and sense‐organ fruit of 30 Prunus domestica L.individuals from 5 types were observed and measured.The tested individuals all showed varying degrees of diversity on each indicator.Among them the variable coeffi‐cient of single fruit weight was the highest,reached 69.82%.The first 11 principal components from cumu‐lative contribution reached 90.632%.The 11 principal components were named factor of fruit weight,factor of leaves size,factor of No.1 leaves shape,factor of No.1 fruit shape and lenticell,factor of internal quality and so on.In cluster analysis,wild Prunus domestica L.,Jiashi Smoked Plum and part of Tacheng Smoked Plum were classified into another one group.However,abroad Prunus domestica L.varieties,Tacheng Binzi and the another part of Tacheng Smoked Plum were classified into a group.The branches‐leaves morpholo‐gy and fruit sense‐organ characters of Prunus domestica L.germplasm resources in Xinj iang had a certain diverse overall,among which there were the richest indicator diversity of fruit sense‐organ characters.In the respect of branches‐leaves morphology and fruit sense‐organ characters,wild Prunus domestica L.and lo‐cal smoked plum were simillar with each other.So abroad Prunus domestica L.varieties and Prunus dom‐estica L.resources in Tacheng were closer to each other.%为探索几类新疆欧洲李种质资源的遗传多样性及亲缘关系差异,对5个类型共30个欧洲李单株的48项枝叶形态及果实感官指标进行观察测定.结果表明,供试单株在各项指标上均展现出不同程度的多样性,其中以单果重的变异系数最高,达到69.82%.提取前11个累计贡献率达90.632%的主成分,依次命名为果实重量因子、叶片大小因子、叶片形状因子1

  9. The normal distribution of thoracoabdominal aorta small branch artery ostia

    International Nuclear Information System (INIS)

    The purpose of this study was to determine the normal distribution of aortic branch artery ostia. CT scans of 100 subjects were retrospectively reviewed. The angular distributions of the aorta with respect to the center of the T3 to L4 vertebral bodies, and of branch artery origins with respect to the center of the aorta were measured. At each vertebral body level the distribution of intercostal/lumbar arteries and other branch arteries were calculated. The proximal descending aorta is posteriorly placed becoming a midline structure, at the thoracolumbar junction, and remains anterior to the vertebral bodies within the abdomen. The intercostal and lumbar artery ostia have a distinct distribution. At each vertebral level from T3 caudally, one intercostal artery originates from the posterior wall of the aorta throughout the thoracic aorta, while the other intercostal artery originates from the medial wall of the descending thoracic aorta high in the chest, posteromedially from the mid-thoracic aorta, and from the posterior wall of the aorta low in the chest. Mediastinal branches of the thoracic aorta originate from the medial and anterior wall. Lumbar branches originate only from the posterior wall of the abdominal aorta. Aortic branch artery origins arise with a bimodal distribution and have a characteristic location. Mediastinal branches of the thoracic aorta originate from the medial and anterior wall. Knowing the location of aortic branch artery ostia may help distinguish branch artery pseudoaneurysms from penetrating ulcers.

  10. [Variability of the celiac artery and its branches in sheep].

    Science.gov (United States)

    Karmona, Kh; Kovachev, G

    1985-01-01

    Contrast matter was used with a total of 363 sheep fetuses, newborn lambs, and adult sheep to study the variability of the coeliac artery and its branches. It was found that the artery and some of its branches, such as arteria ruminalis sinistra, arteria reticularis, and arteria lienalis often showed variations, resp., deviations in their branching and distribution. Others, such as arteria ruminalis dextra and arteria hepatica showed no variations whatever. Both the coeliac artery and the anterior intestinal artery in the sheep were most often shown to branch from the aorta alone (in 71.07 per cent of the cases) as against the rarely observed common truncus coeliacomesentericus (in 28.93 per cent of the cases). The most commonly observed form of branching of arteria coeliaca seemed to be tripus coeliacus, while the branching with the formation of a short truncus hepatogastricus was comparatively a rare phenomenon. It was also established that the left ruminal artery was much more frequently the branch of truncus lienoruminalis than the branch of arteria gastrica sinistra. So far as the place in which arteria reticularis arose three variants were observed. Most frequently this artery was shown to be the branch of arteria gastrica sinistra. PMID:4013078

  11. Branched RNA: A New Architecture for RNA Interference

    Directory of Open Access Journals (Sweden)

    Anna Aviñó

    2011-01-01

    Full Text Available Branched RNAs with two and four strands were synthesized. These structures were used to obtain branched siRNA. The branched siRNA duplexes had similar inhibitory capacity as those of unmodified siRNA duplexes, as deduced from gene silencing experiments of the TNF-α protein. Branched RNAs are considered novel structures for siRNA technology, and they provide an innovative tool for specific gene inhibition. As the method described here is compatible with most RNA modifications described to date, these compounds may be further functionalized to obtain more potent siRNA derivatives and can be attached to suitable delivery systems.

  12. Nuclear science and technology branch report 1975

    International Nuclear Information System (INIS)

    Research programs are reported for the following divisions: Engineering Research, Chemical Technology, Instrumentation and Control, Materials division, Isotopes, Physics, Health Physics, Applied Mathematics and Computing, Radiation Biology Research. The names of staff responsible for each project are indicated. (R.L.)

  13. Synthesis and Characterization of Branched Poly(ester urea)s with Different Branch Density

    Science.gov (United States)

    Yu, Jiayi; Becker, Matthew

    2015-03-01

    A new class of L-phenylalanine-based poly(ester urea)s (PEU) was developed that possess tunable mechanical properties, water uptake ability and degradation rates. Our preliminary data has shown that 1,6-hexanediol L - phenylalanine-based poly(ester urea)s possesses an elastic modulus nearly double that of poly(lactic acid). My work details the synthesis of a series of L - phenylalanine-based poly(ester urea)s possessing a variation in diol chain length and in branch density and shows how these subtle structural differences influence the mechanical properties and in vitro biodegradation rates. The elastic moduli span a range of values that overlap with several currently clinically available degradable polymers. Increasingly the diol chain lengths increases the amount of flexible segment in the chemical structure, which results in reduced elastic modulus values and increased values of elongation at break. Increasing the amount of branch monomer incorporated into the system reduces the molecular entanglement, which also results in decreased elastic modulus values and increased values of elongation at break. The L - phenylalanine-based poly(ester urea)s also exhibited a diol length dependent degradation process that varied between 1-5 % over 16 weeks. Compared with PLLA, PEUs degrade more quickly and the rate can be tuned by changing the diol chain length. PEUs absorb more water and the water uptake ability can be tuned by changing the branch density. This work was supported by Akron Functional Materials Center.

  14. CYANOGEN IN NGC 1851 RED GIANT BRANCH AND ASYMPTOTIC GIANT BRANCH STARS: QUADRIMODAL DISTRIBUTIONS

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, S. W.; Stancliffe, R. J.; Lattanzio, J. C.; Angelou, G. C.; D' Orazi, V. [Monash Centre for Astrophysics, P.O. Box 28M, Victoria 3800 (Australia); Yong, D.; Wylie-de Boer, E. C. [Research School of Astronomy and Astrophysics, Australian National University, Weston, ACT 2611 (Australia); Martell, S. L. [Australian Astronomical Observatory, North Ryde, NSW 2113 (Australia); Grundahl, F. [Department of Physics and Astronomy, Aarhus University, Ny Munkegade, DK-8000 Aarhus C (Denmark); Sneden, C., E-mail: simon.campbell@monash.edu, E-mail: david.yong@anu.edu.au [Department of Astronomy and McDonald Observatory, University of Texas, Austin, TX 78712 (United States)

    2012-12-10

    The Galactic globular cluster NGC 1851 has raised much interest since Hubble Space Telescope photometry revealed that it hosts a double subgiant branch. Here we report on our homogeneous study into the cyanogen (CN) band strengths in the red giant branch (RGB) population (17 stars) and asymptotic giant branch (AGB) population (21 stars) using AAOmega/2dF spectra with R {approx} 3000. We discover that NGC 1851 hosts a quadrimodal distribution of CN band strengths in its RGB and AGB populations. This result supports the merger formation scenario proposed for this cluster, such that the CN quadrimodality could be explained by the superposition of two 'normal' bimodal populations. A small sample overlap with an abundance catalog allowed us to tentatively explore the relationship between our CN populations and a range of elemental abundances. We found a striking correlation between CN and [O/Na]. We also found that the four CN peaks may be paired-the two CN-weaker populations being associated with low Ba and the two CN-stronger populations with high Ba. If true, then s-process abundances would be a good diagnostic for disentangling the two original clusters in the merger scenario. More observations are needed to confirm the quadrimodality and also the relationship between the subpopulations. We also report CN results for NGC 288 as a comparison. Our relatively large samples of AGB stars show that both clusters have a bias toward CN-weak AGB populations.

  15. Mineral resources

    NARCIS (Netherlands)

    Henckens, M.L.C.M.; Ierland, van E.C.; Driessen, P.P.J.; Worrell, E.

    2016-01-01

    The extractable ores of the world's geologically scarcest mineral resources (e.g. antimony, molybdenum and zinc) may be exhausted within several decades to a century, if their extraction continues to increase. This paper explores the likelihood that these scarce mineral resources can be conserved

  16. Quantum Biology

    Directory of Open Access Journals (Sweden)

    Alessandro Sergi

    2009-06-01

    Full Text Available A critical assessment of the recent developmentsof molecular biology is presented.The thesis that they do not lead to a conceptualunderstanding of life and biological systems is defended.Maturana and Varela's concept of autopoiesis is briefly sketchedand its logical circularity avoided by postulatingthe existence of underlying living processes,entailing amplification from the microscopic to the macroscopic scale,with increasing complexity in the passage from one scale to the other.Following such a line of thought, the currently accepted model of condensed matter, which is based on electrostatics and short-ranged forces,is criticized. It is suggested that the correct interpretationof quantum dispersion forces (van der Waals, hydrogen bonding, and so onas quantum coherence effects hints at the necessity of includinglong-ranged forces (or mechanisms for them incondensed matter theories of biological processes.Some quantum effects in biology are reviewedand quantum mechanics is acknowledged as conceptually important to biology since withoutit most (if not all of the biological structuresand signalling processes would not even exist. Moreover, it is suggested that long-rangequantum coherent dynamics, including electron polarization,may be invoked to explain signal amplificationprocess in biological systems in general.

  17. Emergence, hierarchy and top-down causation in evolutionary biology

    OpenAIRE

    Okasha, Samir

    2012-01-01

    The concept of emergence and the related notion of ‘downward causation’ have arisen in numerous branches of science, and have also been extensively discussed in philosophy. Here I examine emergence and downward causation in relation to evolutionary biology. I focus on the old but ongoing discussion in evolutionary biology over the ‘levels of selection’ question, which asks which level(s) of the biological hierarchy natural selection acts at, e.g. the gene, individual, group or species level? ...

  18. Excellent dynamic stability under saturated salt solution for aqueous quantum dots capped by multi-branched ligands

    Science.gov (United States)

    Xu, Jingkun; Xu, Shuhong; Lv, Changgui; Wang, Chunlei; Cui, Yiping

    2016-09-01

    Preparing quantum dots (QDs) with strong stability against salts is extremely important in some environments with ultrahigh salts concentration, such as the oil exploitation, wastewater treatment and biological markers. In this paper, we reported a simple new method to prepared highly stable QDs by using multi-branched ligands. Our results suggested that multi-branched ligands-capped QDs have extremely good dynamic stability even in salt-saturated solution. Unlike to traditional dynamic stability theory, which considers the electrostatic repulsion of QDs dominant QD stability, the current work found a new determined factor: the steric hindrance of ligand structure. The high steric hindrance effect of multi-branched ligands can maintain the single dispersity of QDs even at extremely low electrostatic repulsion. As a result, QDs with ultrahigh stability against salts can be realized.

  19. Vehicle Fleet Information - BMV_LICENSE_BRANCHES_IN: Bureau of Motor Vehicle License Branch Locations in Indiana (Indiana Geological Survey, Point Shapefile)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — BMV_LICENSE_BRANCHES_IN is a point shapefile showing the locations of 142 branch offices of the Indiana Bureau of Motor Vehicles (BMV). Addresses for each branch...

  20. The zygomaticotemporal branch of the trigeminal nerve: an anatomical study.

    Science.gov (United States)

    Totonchi, Ali; Pashmini, Nazly; Guyuron, Bahman

    2005-01-01

    This study was conducted to determine the site of emergence of the zygomaticotemporal branch of the trigeminal nerve from the temporalis muscle and to identify the number of its accessory branches and their locations. A pilot study, conducted on the same number of patients, concluded that the main zygomaticotemporal branch emerges from the deep temporal fascia at a point on average 17 mm lateral and 6 mm cephalad to the lateral palpebral commissure, commonly referred to as the lateral canthus. These measurements, however, were obtained after dissection of the temporal area, rendering the findings less reliable. The current study included 20 consecutive patients, 19 women and one man, between the ages of 26 and 85 years, with an average age of 47.6 years. Those who had a history of previous trauma or surgery in the temple area were excluded. Before the start of the endoscopic forehead procedure, the likely topographic site of the zygomaticotemporal branch was marked 17 mm lateral and 6 mm cephalad to the lateral orbital commissure on the basis of the information extrapolated from the pilot study. The surface mark was then transferred to the deeper layers using a 25-gauge needle stained with brilliant green. After endoscopic exposure of the marked site, the distance between the main branch of the trigeminal nerve or its accessory branches and the tattoo mark was measured in posterolateral and cephalocaudal directions. In addition, the number and locations of the accessory branches of the trigeminal nerve were recorded. On the left side, the average distance of the emergence site of the main zygomaticotemporal branch of the trigeminal nerve from the palpebral fissure was 16.8 mm (range, 12 to 31 mm) in the posterolateral direction and an average of 6.4 mm (range, 4 to 11 mm) in the cephalad direction. On the right side, the average measurements for the main branch were 17.1 mm (range, 15 to 21 mm) in the lateral direction and 6.65 mm (range, 5 to 11 mm) in the

  1. The zygomaticotemporal branch of the trigeminal nerve: an anatomical study.

    Science.gov (United States)

    Totonchi, Ali; Pashmini, Nazly; Guyuron, Bahman

    2005-01-01

    This study was conducted to determine the site of emergence of the zygomaticotemporal branch of the trigeminal nerve from the temporalis muscle and to identify the number of its accessory branches and their locations. A pilot study, conducted on the same number of patients, concluded that the main zygomaticotemporal branch emerges from the deep temporal fascia at a point on average 17 mm lateral and 6 mm cephalad to the lateral palpebral commissure, commonly referred to as the lateral canthus. These measurements, however, were obtained after dissection of the temporal area, rendering the findings less reliable. The current study included 20 consecutive patients, 19 women and one man, between the ages of 26 and 85 years, with an average age of 47.6 years. Those who had a history of previous trauma or surgery in the temple area were excluded. Before the start of the endoscopic forehead procedure, the likely topographic site of the zygomaticotemporal branch was marked 17 mm lateral and 6 mm cephalad to the lateral orbital commissure on the basis of the information extrapolated from the pilot study. The surface mark was then transferred to the deeper layers using a 25-gauge needle stained with brilliant green. After endoscopic exposure of the marked site, the distance between the main branch of the trigeminal nerve or its accessory branches and the tattoo mark was measured in posterolateral and cephalocaudal directions. In addition, the number and locations of the accessory branches of the trigeminal nerve were recorded. On the left side, the average distance of the emergence site of the main zygomaticotemporal branch of the trigeminal nerve from the palpebral fissure was 16.8 mm (range, 12 to 31 mm) in the posterolateral direction and an average of 6.4 mm (range, 4 to 11 mm) in the cephalad direction. On the right side, the average measurements for the main branch were 17.1 mm (range, 15 to 21 mm) in the lateral direction and 6.65 mm (range, 5 to 11 mm) in the

  2. Introduction to the police scientific development branch

    International Nuclear Information System (INIS)

    Full text: The Police Scientific Development Branch (Pdb) of the UK Home Office evaluates technologies, develops equipment and detection standards for the police and security communities. PSDB's guidance helps to protect critical sites, including nuclear sites, in the United Kingdom. PSDB evaluates doors, walls, fences, locks, glazing and other barrier to determine whether they meet national and European standards against conventional physical attack. PSDB also evaluates intruder-detection systems. If solutions for security problems do not exist commercially, it might help to develop them. Examples include computer machine-vision systems to guide a pan-tilt-zoom camera automatically, and to assess intruder alarms. PSDB's automatic alarm verification system (AMETHYST) is now being installed for test at a nuclear power station on England's south coast. PSDB has used its analysis of the effects of exploding bombs on building materials to influence building codes. The PSDB also evaluates technologies for crime investigation, surveillance, explosive detection and bomb search. PSDB uses its experience to help train security practitioners to select, specify, and audit security at critical sites, including sites that handle nuclear materials. PSDB's technologies and advice have helped to protect the UK against terrorist attacks. Its expertise can be made available to help meet other European needs. (author)

  3. Ventricular fiber optimization utilizing the branching structure.

    Science.gov (United States)

    Washio, Takumi; Yoneda, Kazunori; Okada, Jun-Ichi; Kariya, Taro; Sugiura, Seiryo; Hisada, Toshiaki

    2016-07-01

    In this paper, we propose an algorithm that optimizes the ventricular fiber structure of the human heart. A number of histological studies and diffusion tensor magnetic resonance imaging analyses have revealed that the myocardial fiber forms a right-handed helix at the endocardium. However, the fiber formation changes its orientation as a function of transmural depth, becoming a left-handed helix at the epicardium. To determine how nature can construct such a structure, which obtains surprising pumping performance, we introduce macroscopic modeling of the branching structure of cardiac myocytes in our finite element ventricular model and utilize this in an optimization process. We put a set of multidirectional fibers around a central fiber orientation at each point of the ventricle walls and simulate heartbeats by generating contraction forces along each of these directions. We examine two optimization processes using the workloads or impulses measured in these directions to update the central fiber orientation. Both processes improve the pumping performance towards an optimal value within several tens of heartbeats, starting from an almost-flat fiber orientation. However, compared with the workload optimization, the impulse optimization produces better agreement with experimental studies on transmural changes of fiber helix angle, streamline patterns of characteristic helical structures, and temporal changes in strain. Furthermore, the impulse optimization is robust under geometrical changes of the heart and tends to homogenize various mechanical factors such as the stretch and stretch rate along the fiber orientation, the contraction force, and energy consumption. Copyright © 2015 John Wiley & Sons, Ltd. PMID:26453026

  4. Clinical trials in branch retinal vein occlusion

    Directory of Open Access Journals (Sweden)

    Tandava Krishnan Panakanti

    2016-01-01

    Full Text Available Branch retinal vein occlusion (BRVO is the second most common retinal vascular disorder. The management of macular edema has changed considerably over time. The laser is considered the gold standard treatment for over two decades. However, visual recovery with laser is usually slow and incomplete. The advent of intravitreal agents, specifically anti-vascular endothelial growth factors (VEGF have heralded a new era which promises rapid recovery of vision and quality of vision. Randomized clinical trials have reported optimal results with anti-VEGF agents (ranibizumab, bevacizumab, and aflibercept compared to laser therapy or steroids. However, nearly 50% of the patients require repeat intravitreal anti-VEGF therapy up to 4 years after initiating therapy to sustain the visual gains. The adverse events (systemic and ocular of these agents are minimal. Monotherapy with anti-VEGF agents have been found to provide better results than any combination with laser. This review article summarizes evidence from randomized controlled trials evaluating treatment options for the treatment of macular edema secondary to BRVO with a special focus on anti-VEGF therapy.

  5. Quantum Biology

    CERN Document Server

    Sergi, Alessandro

    2009-01-01

    A critical assessment of the recent developments of molecular biology is presented. The thesis that they do not lead to a conceptual understanding of life and biological systems is defended. Maturana and Varela's concept of autopoiesis is briefly sketched and its logical circularity avoided by postulating the existence of underlying {\\it living processes}, entailing amplification from the microscopic to the macroscopic scale, with increasing complexity in the passage from one scale to the other. Following such a line of thought, the currently accepted model of condensed matter, which is based on electrostatics and short-ranged forces, is criticized. It is suggested that the correct interpretation of quantum dispersion forces (van der Waals, hydrogen bonding, and so on) as quantum coherence effects hints at the necessity of including long-ranged forces (or mechanisms for them) in condensed matter theories of biological processes. Some quantum effects in biology are reviewed and quantum mechanics is acknowledge...

  6. Management of human resources in the corporate sector

    OpenAIRE

    Soukupová, Klára

    2014-01-01

    This thesis "Management of human resources in the corporate sector" deal with necessity, operation and care of human resources in the corporate sector, the main objective is to propose on the basis of the detected weaknesses improvement measures in the field of human resources activities of selected company. Nowadays great emphasis is placed on knowledge and skills of workers in any branch and companies are often forced to reduce their staff requirements, however, they do not always realize t...

  7. Radiolabeled dimethyl branched long chain fatty acid for heart imaging

    Science.gov (United States)

    Knapp, Jr., Furn F.; Goodman, Mark M.; Kirsch, Gilbert

    1988-08-16

    A radiolabeled long chain fatty acid for heart imaging that has dimethyl branching at one of the carbons of the chain which inhibits the extent to which oxidation can occur. The closer to the carboxyl the branching is positioned, the more limited the oxidation, thereby resulting in prolonged retention of the radiolabeled compound in the heart.

  8. 33 CFR 117.927 - Coosaw River (Whale Branch).

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Coosaw River (Whale Branch). 117.927 Section 117.927 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... (Whale Branch). The draw of the Seaboard System Railroad bridge, mile 5.3 at Seabrook, and the draw...

  9. The Horizontal Branch of the Sculptor Dwarf galaxy

    NARCIS (Netherlands)

    Salaris, Maurizio; Boer, Thomas de; Tolstoy, Eline; Fiorentino, Giuliana; Cassisi, Santi

    2013-01-01

    We have performed the first detailed simulation of the horizontal branch of the Sculptor dwarf spheroidal galaxy by means of synthetic modelling techniques, taking consistently into account the star formation history and metallicity evolution as determined from the main sequence and red giant branch

  10. Dorzolamide increases retinal oxygen tension after branch retinal vein occlusion

    DEFF Research Database (Denmark)

    Noergaard, Michael Hove; Bach-Holm, Daniella; Scherfig, Erik;

    2008-01-01

    To study the effect of dorzolamide on the preretinal oxygen tension (RPO(2)) in retinal areas affected by experimental branch retinal vein occlusion (BRVO) in pigs.......To study the effect of dorzolamide on the preretinal oxygen tension (RPO(2)) in retinal areas affected by experimental branch retinal vein occlusion (BRVO) in pigs....

  11. Preventing Death and Serious Injury from Falling Trees and Branches

    Science.gov (United States)

    Brookes, Andrew

    2007-01-01

    Of 128 outdoor education related deaths examined since 1960, 14 have been due to falling trees or branches. This article examines the grounds on which death or serious injury due to falling trees or branches can be regarded as an inherent risk in outdoor education, and the extent to which such incidents can be regarded as preventable. It compares…

  12. Tiling branching multiplicity spaces with GL2 pattern blocks

    OpenAIRE

    Kim, Sangjib

    2012-01-01

    We study branching multiplicity spaces of complex classical groups in terms of GL(2) representations. In particular, we show how combinatorics of GL(2) representations are intertwined to make branching rules under the restriction of GL(n) to GL(n-2). We also discuss analogous results for the symplectic and orthogonal groups.

  13. Branched nanostructures and method of synthesizing the same

    Science.gov (United States)

    Fonseca, Luis F. (Inventor); Resto, Oscar (Inventor); Sola, Francisco (Inventor)

    2009-01-01

    A branched nanostructure is synthesized. A porous material, with pores having a diameter of approximately 1 .mu.m or less, is placed in a vacuum. It is irradiated with an electron beam. This causes a trunk to grow from the porous material and further causes branches to grow from the trunk.

  14. Aggregation Dynamics Using Phase Wave Signals and Branching Patterns

    Science.gov (United States)

    Sakaguchi, Hidetsugu; Kusagaki, Takuma

    2016-09-01

    The aggregation dynamics of slime mold is studied using coupled equations of phase ϕ and cell concentration n. Phase waves work as tactic signals for aggregation. Branching structures appear during the aggregation. A stationary branching pattern appears like a river network, if cells are uniformly supplied into the system.

  15. 20 CFR 422.5 - District offices and branch offices.

    Science.gov (United States)

    2010-04-01

    ... Section 422.5 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Organization and Functions of the Social Security Administration § 422.5 District offices and branch offices. There are over 700 social security district offices and branch offices located in the principal cities...

  16. Why a Particle Physicist is Interested in DNA Branch Migration

    CERN Document Server

    Myers, E; Myers, Eric; Bruist, Michael F.

    1996-01-01

    We describe an explicitly discrete model of the process of DNA branch migration. The model matches the existing data well, but we find that branch migration along long strands of DNA ($N \\simge 40$~bp) is also well modeled by continuum diffusion. The discrete model is still useful for guiding future experiments.

  17. A random walk with a branching system in random environments

    Institute of Scientific and Technical Information of China (English)

    Ying-qiu LI; Xu LI; Quan-sheng LIU

    2007-01-01

    We consider a branching random walk in random environments, where the particles are reproduced as a branching process with a random environment (in time), and move independently as a random walk on Z with a random environment (in locations). We obtain the asymptotic properties on the position of the rightmost particle at time n, revealing a phase transition phenomenon of the system.

  18. Connecting to Community: Best Practices for Designing a Digital Branch

    Science.gov (United States)

    Bird, Nora J.; Pampaloni, Andrea M.

    2014-01-01

    In this article the authors provide an overview of the concept of a digital branch library and the manner in which it can be used to enhance academic library community engagement. As the front door to the branch, the library's Website is key to going beyond service provision toward sustaining relationships with faculty, students, staff, and…

  19. Mineral Resources

    OpenAIRE

    Ababsa, Myriam

    2014-01-01

    Jordan’s natural resources are very limited: water is scarce, there is little arable land and the country has few sources of energy (fig. I.11). Jordan’s mineral industry has a long history: flint was used in prehistoric times and early copper mining started in Wadi Faynan during the Chalcolithic Period. The following is a brief presentation of Jordan’s resources. Mining and investments will be studied in Part 3. Figure I.11 — Jordan Mineral Resources. NRA 2012 Phosphates The Jordanian Natur...

  20. Distinct structures of the α-fucose branches in fucosylated chondroitin sulfates do not affect their anticoagulant activity.

    Science.gov (United States)

    Santos, Gustavo R C; Glauser, Bianca F; Parreiras, Luane A; Vilanova, Eduardo; Mourão, Paulo A S

    2015-10-01

    Fucosylated chondroitin sulfate (FCS) is a glycosaminoglycan found in sea cucumbers. It has a backbone like that of mammalian chondroitin sulfate (4-β-d-GlcA-1→3-β-d-GalNAc-1)n but substituted at the 3rd position of the β-d-glururonic acid residues with α-fucose branches. The structure of these branches varies among FCSs extracted from different species of sea cucumbers, as revealed by solution NMR spectroscopy. Some species (Isostichopus badionotus and Patalus mollis) contain branches formed by single α-fucose residues but with variable sulfation patterns (2,4-, 3,4- and 4-sulfation). FCS from Ludwigothurea grisea is distinguished because it contains preponderant branches formed by disaccharide units containing non-sulfated and 3-sulfated α-fucose units at the reducing and non-reducing ends, respectively. Despite the structural variability on their α-fucose branches, these FCSs have similar anticoagulant action on assays using purified reagents. They have serpin-dependent and serpin-independent effects. Pharmacological assays using experimental animals showed that the three types of FCSs have similar antithrombotic effect and bleeding tendency. They also activate factor XII on the same range of concentration. Based on these observations, we proposed that only few sulfated α-fucose branches along the FCS chain are enough to assure the binding of this glycosaminoglycan to proteins of the coagulation system. Substitution with additional sulfated α-fucose does not increase further the activity. Overall, the use of FCSs with marked variability on their branches of α-fucose allowed us to establish correlations between structures vs biological effects of these glycosaminoglycans on a more refined basis. It opens new avenues for therapeutic intervention using FCSs.

  1. Flood of October 8, 1962, on Bachman Branch and Joes Creek at Dallas, Texas

    Science.gov (United States)

    Ruggles, Frederick H.

    1966-01-01

    This report presents hydrologic data that enable the user to define areas susceptible to flooding and to evaluate the flood hazard along Bachman Branch and Joes Creek. The data provide a technical basis for making sound decisions concerning the use of flood-plain lands. The report will be useful for preparing building and zoning regulations, locating waste disposal facilities, purchasing unoccupied land, developing recreational areas, and managing surface water in relation to ground-water resources. This is one of the series of reports delineating the flood hazard on streams in the Dallas area.

  2. Bayesian and maximum likelihood phylogenetic analyses of protein sequence data under relative branch-length differences and model violation

    Directory of Open Access Journals (Sweden)

    Harlow Timothy J

    2005-01-01

    Bayesian prior on branch lengths did not improve, and under certain extreme conditions significantly diminished, performance. The two topology-comparison metrics we employed, edit distance and Robinson-Foulds symmetric distance, yielded different but highly complementary measures of performance. Conclusions Our results demonstrate that Bayesian inference can be relatively robust against biologically reasonable levels of relative branch-length differences and model violation, and thus may provide a promising alternative to maximum likelihood for inference of phylogenetic trees from protein-sequence data.

  3. Immediate Small Side Branch Occlusion after Percutaneous Coronary Intervention

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Ostovan

    2007-09-01

    Full Text Available Background: Small side branches, albeit less important than their larger counterparts, have not yet received due attention in the literature. Nor has there ever been a comparison between drug-eluting stents and bare metal stents apropos side branch occlusion. The aim of this study was to compare the patency of small (≥0.5 and ≤1.5 mm in diameter side branches with respect to bare metal vs. drug-eluting stents immediately after their deployment.Methods: This prospective bi-center study, conducted between June 2005 and January 2007, enrolled 82 patients treated with ≥1 of two stents (TAXUSTM LiberteTM or LiberteTM. Side branches ≥0.5 and <1.5 mm in diameter arising from the main vessel at the lesion site were evaluated. Results: Thirty-eight patients were treated with 42 LiberteTM stents (58 side branches and forty-four patients with 50 TAXUSTM LiberteTM (102 side branches. The rate of small side branch occlusion was 35.3% (36 in the TAXUSTM LiberteTM group compared to 29.31% (15 in the LiberteTM group (P-value= 0.7. The presence of type 1 side branch morphology (Lefevre classification was the most powerful predictor of small side branch occlusion (P-value=0.03. Conclusion: This study shows that drug-eluting stents are not inferior to bare metal stents as regards small side branch occlusion during coronary stenting

  4. Depression - resources

    Science.gov (United States)

    Resources - depression ... Depression is a medical condition. If you think you may be depressed, see a health care provider. ... following organizations are good sources of information on depression : American Psychological Association -- www.apa.org/topics/depress/ ...

  5. Seaweed resources

    Digital Repository Service at National Institute of Oceanography (India)

    Deshmukhe, G.V.; Dhargalkar, V.K.; Untawale, A.G.

    The chapter summarizes our present knowledge of the seaweed resources of the Indian Ocean region with regard to the phytogeographical distribution, composition, biomass, utilization, cultivation, conservation and management. The voluminous data...

  6. Diabetes - resources

    Science.gov (United States)

    Resources - diabetes ... The following sites provide further information on diabetes: American Diabetes Association -- www.diabetes.org Juvenile Diabetes Research Foundation International -- www.jdrf.org National Center for Chronic Disease Prevention and Health Promotion -- ...

  7. Mineral resources

    Digital Repository Service at National Institute of Oceanography (India)

    Valsangkar, A.B.

    to the source, supply rate, sediment type and seabed topography. Indian Ocean is second largest and least explored for nonrenewable resources. Compared to deep-sea, relatively better knowledge is available for the near shore deposits. A concise account...

  8. Arthritis - resources

    Science.gov (United States)

    Resources - arthritis ... The following organizations provide more information on arthritis : American Academy of Orthopaedic Surgeons -- orthoinfo.aaos.org/menus/arthritis.cfm Arthritis Foundation -- www.arthritis.org Centers for Disease Control and Prevention -- www. ...

  9. Hemophilia - resources

    Science.gov (United States)

    Resources - hemophilia ... The following organizations provide further information on hemophilia : Centers for Disease Control and Prevention -- www.cdc.gov/ncbddd/hemophilia/index.html National Heart, Lung, and Blood Institute -- www.nhlbi.nih.gov/ ...

  10. Diabetes - resources

    Science.gov (United States)

    Resources - diabetes ... The following sites provide further information on diabetes : American Diabetes Association -- www.diabetes.org Juvenile Diabetes Research Foundation International -- www.jdrf.org National Center for Chronic Disease Prevention and Health Promotion -- ...

  11. Flight Planning Branch Space Shuttle Lessons Learned

    Science.gov (United States)

    Price, Jennifer B.; Scott, Tracy A.; Hyde, Crystal M.

    2011-01-01

    Planning products and procedures that allow the mission flight control teams and the astronaut crews to plan, train and fly every Space Shuttle mission have been developed by the Flight Planning Branch at the NASA Johnson Space Center. As the Space Shuttle Program ends, lessons learned have been collected from each phase of the successful execution of these Shuttle missions. Specific examples of how roles and responsibilities of console positions that develop the crew and vehicle attitude timelines will be discussed, as well as techniques and methods used to solve complex spacecraft and instrument orientation problems. Additionally, the relationships and procedural hurdles experienced through international collaboration have molded operations. These facets will be explored and related to current and future operations with the International Space Station and future vehicles. Along with these important aspects, the evolution of technology and continual improvement of data transfer tools between the shuttle and ground team has also defined specific lessons used in the improving the control teams effectiveness. Methodologies to communicate and transmit messages, images, and files from Mission Control to the Orbiter evolved over several years. These lessons have been vital in shaping the effectiveness of safe and successful mission planning that have been applied to current mission planning work in addition to being incorporated into future space flight planning. The critical lessons from all aspects of previous plan, train, and fly phases of shuttle flight missions are not only documented in this paper, but are also discussed as how they pertain to changes in process and consideration for future space flight planning.

  12. Forest Resources

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-06-01

    Forest biomass is an abundant biomass feedstock that complements the conventional forest use of wood for paper and wood materials. It may be utilized for bioenergy production, such as heat and electricity, as well as for biofuels and a variety of bioproducts, such as industrial chemicals, textiles, and other renewable materials. The resources within the 2016 Billion-Ton Report include primary forest resources, which are taken directly from timberland-only forests, removed from the land, and taken to the roadside.

  13. Mars resources

    Science.gov (United States)

    Duke, Michael B.

    1986-01-01

    The most important resources of Mars for the early exploration phase will be oxygen and water, derived from the Martian atmosphere and regolith, which will be used for propellant and life support. Rocks and soils may be used in unprocessed form as shielding materials for habitats, or in minimally processed form to expand habitable living and work space. Resources necessary to conduct manufacturing and agricultural projects are potentially available, but will await advanced stages of Mars habitation before they are utilized.

  14. Synthesis of branched polyglucans by the tandem action of potato phosphorylase and Deinococcus geothermalis glycogen branching enzyme

    NARCIS (Netherlands)

    van der Vlist, Jeroen; Reixach, Marta Palomo; van der Maarel, Marc; Dijkhuizen, Lubbert; Schouten, Arend Jan; Loos, Katja

    2008-01-01

    An enzymatic tandem reaction is described in which the enzymes phosphorylase and Deinococcus geothermalis glycogen branching enzyme (Dg GBE) catalyze the synthesis of branched polyglucans from glucose-1-phosphate (G-1-P). Phosphorylase consumes G-1-P and polymerizes linear amylose while DR GBE intro

  15. Epithelial inactivation of Yy1 abrogates lung branching morphogenesis.

    Science.gov (United States)

    Boucherat, Olivier; Landry-Truchon, Kim; Bérubé-Simard, Félix-Antoine; Houde, Nicolas; Beuret, Laurent; Lezmi, Guillaume; Foulkes, William D; Delacourt, Christophe; Charron, Jean; Jeannotte, Lucie

    2015-09-01

    Yin Yang 1 (YY1) is a multifunctional zinc-finger-containing transcription factor that plays crucial roles in numerous biological processes by selectively activating or repressing transcription, depending upon promoter contextual differences and specific protein interactions. In mice, Yy1 null mutants die early in gestation whereas Yy1 hypomorphs die at birth from lung defects. We studied how the epithelial-specific inactivation of Yy1 impacts on lung development. The Yy1 mutation in lung epithelium resulted in neonatal death due to respiratory failure. It impaired tracheal cartilage formation, altered cell differentiation, abrogated lung branching and caused airway dilation similar to that seen in human congenital cystic lung diseases. The cystic lung phenotype in Yy1 mutants can be partly explained by the reduced expression of Shh, a transcriptional target of YY1, in lung endoderm, and the subsequent derepression of mesenchymal Fgf10 expression. Accordingly, SHH supplementation partially rescued the lung phenotype in vitro. Analysis of human lung tissues revealed decreased YY1 expression in children with pleuropulmonary blastoma (PPB), a rare pediatric lung tumor arising during fetal development and associated with DICER1 mutations. No evidence for a potential genetic interplay between murine Dicer and Yy1 genes during lung morphogenesis was observed. However, the cystic lung phenotype resulting from the epithelial inactivation of Dicer function mimics the Yy1 lung malformations with similar changes in Shh and Fgf10 expression. Together, our data demonstrate the crucial requirement for YY1 in lung morphogenesis and identify Yy1 mutant mice as a potential model for studying the genetic basis of PPB. PMID:26329601

  16. Biological conditions for oscillations and chaos generated by multispecies competition

    NARCIS (Netherlands)

    Huisman, J; Weissing, FJ

    2001-01-01

    We investigate biological mechanisms that generate oscillations and chaos in multispecies competition models. For this purpose, we use a competition model concerned with competition for abiotic essential resources. Because phytoplankton and plants consume quite a number of abiotic essential resource

  17. Using multitype branching processes to quantify statistics of disease outbreaks in zoonotic epidemics

    Science.gov (United States)

    Singh, Sarabjeet; Schneider, David J.; Myers, Christopher R.

    2014-03-01

    Branching processes have served as a model for chemical reactions, biological growth processes, and contagion (of disease, information, or fads). Through this connection, these seemingly different physical processes share some common universalities that can be elucidated by analyzing the underlying branching process. In this work we focus on coupled branching processes as a model of infectious diseases spreading from one population to another. An exceedingly important example of such coupled outbreaks are zoonotic infections that spill over from animal populations to humans. We derive several statistical quantities characterizing the first spillover event from animals to humans, including the probability of spillover, the first passage time distribution for human infection, and disease prevalence in the animal population at spillover. Large stochastic fluctuations in those quantities can make inference of the state of the system at the time of spillover difficult. Focusing on outbreaks in the human population, we then characterize the critical threshold for a large outbreak, the distribution of outbreak sizes, and associated scaling laws. These all show a strong dependence on the basic reproduction number in the animal population and indicate the existence of a novel multicritical point with altered scaling behavior. The coupling of animal and human infection dynamics has crucial implications, most importantly allowing for the possibility of large human outbreaks even when human-to-human transmission is subcritical.

  18. Novel, deep-branching heterotrophic bacterial populations recovered from thermal spring metagenomes

    Directory of Open Access Journals (Sweden)

    Daniel R Colman

    2016-03-01

    Full Text Available Thermal spring ecosystems are a valuable resource for the discovery of novel hyperthermophilic Bacteria and Archaea, and harbor deeply-branching lineages that provide insight regarding the nature of early microbial life. We characterized bacterial populations in two circumneutral (pH ~ 8 Yellowstone National Park thermal (T ~ 80 oC spring filamentous ‘streamer’ communities using random metagenomic DNA sequence to investigate the metabolic potential of these novel populations. Four de novo assemblies representing three abundant, deeply-branching bacterial phylotypes were recovered. Analysis of conserved phylogenetic marker genes indicated that two of the phylotypes represent separate groups of an uncharacterized phylum (for which we propose the candidate phylum name ‘Pyropristinus’. The third new phylotype falls within the proposed Calescamantes phylum. Metabolic reconstructions of the 'Pyropristinus' and Calescamantes populations showed that these organisms appear to be chemoorganoheterotrophs, and have the genomic potential for aerobic respiration and oxidative phosphorylation via archaeal-like V-type, and bacterial F-type ATPases, respectively. A survey of similar phylotypes (> 97% nt identity within 16S rRNA gene datasets suggest that the newly described organisms are restricted to terrestrial thermal springs ranging from 70 - 90 oC and pH values of ~ 7 - 9. The characterization of these lineages is important for understanding the diversity of deeply-branching bacterial phyla, and their functional role in high-temperature circumneutral ‘streamer’ communities.

  19. Biological Oceanography

    Science.gov (United States)

    Abbott, M. R.

    1984-01-01

    Within the framework of global biogeochemical cycles and ocean productivity, there are two areas that will be of particular interest to biological oceanography in the 1990s. The first is the mapping in space time of the biomass and productivity of phytoplankton in the world ocean. The second area is the coupling of biological and physical processes as it affects the distribution and growth rate of phytoplankton biomass. Certainly other areas will be of interest to biological oceanographers, but these two areas are amenable to observations from satellites. Temporal and spatial variability is a regular feature of marine ecosystems. The temporal and spatial variability of phytoplankton biomass and productivity which is ubiquitous at all time and space scales in the ocean must be characterized. Remote sensing from satellites addresses these problems with global observations of mesocale (2 to 20 days, 10 to 200 km) features over a long period of time.

  20. Moon Prospective Energy and Material Resources

    CERN Document Server

    2012-01-01

    The Earth has limited material and energy resources. Further development of the humanity will require going beyond our planet for mining and use of extraterrestrial mineral resources and search of power sources. The exploitation of the natural resources of the Moon is a first natural step on this direction. Lunar materials may contribute to the betterment of conditions of people on Earth but they also may be used to establish permanent settlements on the Moon. This will allow developing new technologies, systems and flight operation techniques to continue space exploration.   In fact, a new branch of human civilization could be established permanently on Moon in the next century. But, meantime, an inventory and proper social assessment of Moon’s prospective energy and material resources is required. This book investigates the possibilities and limitations of various systems supplying manned bases on Moon with energy and other vital resources. The book collects together recent proposals and innovative optio...

  1. Processability improvement of polyolefins through radiation-induced branching

    Science.gov (United States)

    Cheng, Song; Phillips, Ed; Parks, Lewis

    2010-03-01

    Radiation-induced long-chain branching for the purpose of improving melt strength and hence the processability of polypropylene (PP) and polyethylene (PE) is reviewed. Long-chain branching without significant gel content can be created by low dose irradiation of PP or PE under different atmospheres, with or without multifunctional branching promoters. The creation of long-chain branching generally leads to improvement of melt strength, which in turn may be translated into processability improvement for specific applications in which melt strength plays an important role. In this paper, the changes of the melt flow rate and the melt strength of the irradiated polymer and the relationship between long-chain branching and melt strength are reviewed. The effects of the atmosphere and the branching promoter on long-chain branching vs. degradation are discussed. The benefits of improved melt strength on the processability, e.g., sag resistance and strain hardening, are illustrated. The implications on practical polymer processing applications such as foams and films are also discussed.

  2. Optimization of multi-branch switched diversity systems

    KAUST Repository

    Nam, Haewoon

    2009-10-01

    A performance optimization based on the optimal switching threshold(s) for a multi-branch switched diversity system is discussed in this paper. For the conventional multi-branch switched diversity system with a single switching threshold, the optimal switching threshold is a function of both the average channel SNR and the number of diversity branches, where computing the optimal switching threshold is not a simple task when the number of diversity branches is high. The newly proposed multi-branch switched diversity system is based on a sequence of switching thresholds, instead of a single switching threshold, where a different diversity branch uses a different switching threshold for signal comparison. Thanks to the fact that each switching threshold in the sequence can be optimized only based on the number of the remaining diversity branches, the proposed system makes it easy to find these switching thresholds. Furthermore, some selected numerical and simulation results show that the proposed switched diversity system with the sequence of optimal switching thresholds outperforms the conventional system with the single optimal switching threshold. © 2009 IEEE.

  3. Coset construction of logarithmic minimal models: branching rules and branching functions

    CERN Document Server

    Pearce, Paul A

    2013-01-01

    Working in the Virasoro picture, it is argued that the logarithmic minimal models LM(p,p')=LM(p,p';1) can be extended to an infinite hierarchy of logarithmic conformal field theories LM(p,p';n) at higher fusion levels n=1,2,3,.... From the lattice, these theories are constructed by fusing together n x n elementary faces of the appropriate LM(p,p') models. It is further argued that all of these logarithmic theories are realized as diagonal cosets (A_1^{(1)})_k \\oplus (A_1^{(1)})_n / (A_1^{(1)})_{k+n} where n is the integer fusion level and k=np/(p'-p)-2 is a fractional level. These cosets mirror the cosets of the higher fusion level minimal models of the form M(m,m';n), but are associated with certain reducible representations. We present explicit branching rules for characters in the form of multiplication formulas arising in the logarithmic limit of the usual Goddard-Kent-Olive coset construction of the non-unitary minimal models M(m,m';n). The limiting branching functions play the role of Kac characters for...

  4. Role of mitochondrial transamination in branched chain amino acid metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Hutson, S.M.; Fenstermacher, D.; Mahar, C.

    1988-03-15

    Oxidative decarboxylation and transamination of 1-/sup 14/C-branched chain amino and alpha-keto acids were examined in mitochondria isolated from rat heart. Transamination was inhibited by aminooxyacetate, but not by L-cycloserine. At equimolar concentrations of alpha-ketoiso(1-/sup 14/C)valerate (KIV) and isoleucine, transamination was increased by disrupting the mitochondria with detergent which suggests transport may be one factor affecting the rate of transamination. Next, the subcellular distribution of the aminotransferase(s) was determined. Branched chain aminotransferase activity was measured using two concentrations of isoleucine as amino donor and (1-/sup 14/C)KIV as amino acceptor. The data show that branched chain aminotransferase activity is located exclusively in the mitochondria in rat heart. Metabolism of extramitochondrial branched chain alpha-keto acids was examined using 20 microM (1-/sup 14/C)KIV and alpha-ketoiso(1-/sup 14/C)caproate (KIC). There was rapid uptake and oxidation of labeled branched chain alpha-keto acid, and, regardless of the experimental condition, greater than 90% of the labeled keto acid substrate was metabolized during the 20-min incubation. When a branched chain amino acid (200 microM) or glutamate (5 mM) was present, 30-40% of the labeled keto acid was transaminated while the remainder was oxidized. Provision of an alternate amino acceptor in the form of alpha-keto-glutarate (0.5 mM) decreased transamination of the labeled KIV or KIC and increased oxidation. Metabolism of intramitochondrially generated branched chain alpha-keto acids was studied using (1-/sup 14/C)leucine and (1-/sup 14/C)valine. Essentially all of the labeled branched chain alpha-keto acid produced by transamination of (1-/sup 14/C)leucine or (1-/sup 14/C)valine with a low concentration of unlabeled branched chain alpha-keto acid (20 microM) was oxidized.

  5. Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated chondroitin sulfate.

    Science.gov (United States)

    Wu, Nian; Zhang, Yu; Ye, Xingqian; Hu, Yaqin; Ding, Tian; Chen, Shiguo

    2016-08-20

    Fucosylated chondroitin sulfates (fCSs) are glycosaminoglycans extracted from sea cucumbers, consisting of chondroitin sulfate E (CSE) backbones and sulfated fucose branches. The biological properties of fCSs could be affected by the sulfation pattern of their fucose branches. In the present study, two fCSs were isolated from sea cucumbers Isostichopus badionotus (fCS-Ib) and Pearsonothuria graeffei (fCS-Pg). Their monosaccharide compositions of glucuronic acid (GlcA), N-acetylgalactosamine (GalNAc), fucose (Fuc) and sulfate were at similar molar ratio with 1.0/0.7/0.9/3.1 for fCS-Ib and 1.0/0.8/1.5/2.6 for fCS-Pg. The two fCSs have different sulfation patterns on their fucose branches, fCS-Pg with 3,4-O-disulfation while fCS-Ib with 2,4-O-disulfation. Their antihyperlipidemic effects were compared using a high-fat high-fructose diet (HFFD)-fed C57BL/6J mice model. Both fCS-Ib and fCS-Pg had significant effects on lipid profile improvement, liver protection, blood glucose diminution and hepatic glycogen synthesis. Specifically, fCS-Pg with 3,4-O-disulfation fucose branches was more effective in reduction of blood cholesterol (TC), low density lipoprotein (LDL) and atherogenic index (AI). Our results indicate that both fCSs, especially fCS-Pg, could be used as a potential anti-hyperlipidemic drug. PMID:27178902

  6. Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated chondroitin sulfate.

    Science.gov (United States)

    Wu, Nian; Zhang, Yu; Ye, Xingqian; Hu, Yaqin; Ding, Tian; Chen, Shiguo

    2016-08-20

    Fucosylated chondroitin sulfates (fCSs) are glycosaminoglycans extracted from sea cucumbers, consisting of chondroitin sulfate E (CSE) backbones and sulfated fucose branches. The biological properties of fCSs could be affected by the sulfation pattern of their fucose branches. In the present study, two fCSs were isolated from sea cucumbers Isostichopus badionotus (fCS-Ib) and Pearsonothuria graeffei (fCS-Pg). Their monosaccharide compositions of glucuronic acid (GlcA), N-acetylgalactosamine (GalNAc), fucose (Fuc) and sulfate were at similar molar ratio with 1.0/0.7/0.9/3.1 for fCS-Ib and 1.0/0.8/1.5/2.6 for fCS-Pg. The two fCSs have different sulfation patterns on their fucose branches, fCS-Pg with 3,4-O-disulfation while fCS-Ib with 2,4-O-disulfation. Their antihyperlipidemic effects were compared using a high-fat high-fructose diet (HFFD)-fed C57BL/6J mice model. Both fCS-Ib and fCS-Pg had significant effects on lipid profile improvement, liver protection, blood glucose diminution and hepatic glycogen synthesis. Specifically, fCS-Pg with 3,4-O-disulfation fucose branches was more effective in reduction of blood cholesterol (TC), low density lipoprotein (LDL) and atherogenic index (AI). Our results indicate that both fCSs, especially fCS-Pg, could be used as a potential anti-hyperlipidemic drug.

  7. Law related to management of natural resources And the determination of Its environment

    OpenAIRE

    VISHAWAS CHOUHAN

    2012-01-01

    With the help of my article I am discovering hypothesis about the law related to management of natural resources and present environment law & critical analysis of its environment effect. It is my belief that is root of origin of “Law” or origin of “Statutes” in world the main reason was the management of natural resources. On this basis it is necessary to add a new branch – Environment School of Jurisprudence in the branches of Jurisprudence.

  8. A BRANCH AND BOUND ALGORITHM FOR SEPARABLE CONCAVE PROGRAMMING

    Institute of Scientific and Technical Information of China (English)

    Hong-gang Xue; Cheng-xian; Feng-min Xu

    2004-01-01

    In this paper, we propose a new branch and bound algorithm for the solution of large scale separable concave programming problems. The largest distance bisection (LDB)technique is proposed to divide rectangle into sub-rectangles when one problem is branched into two subproblems. It is proved that the LDB method is a normal rectangle subdivision(NRS). Numerical tests on problems with dimensions from 100 to 10000 show that the proposed branch and bound algorithm is efficient for solving large scale separable concave programming problems, and convergence rate is faster than ω-subdivision method.

  9. Phenomenological picture of fluctuations in branching random walks.

    Science.gov (United States)

    Mueller, A H; Munier, S

    2014-10-01

    We propose a picture of the fluctuations in branching random walks, which leads to predictions for the distribution of a random variable that characterizes the position of the bulk of the particles. We also interpret the 1/sqrt[t] correction to the average position of the rightmost particle of a branching random walk for large times t≫1, computed by Ebert and Van Saarloos, as fluctuations on top of the mean-field approximation of this process with a Brunet-Derrida cutoff at the tip that simulates discreteness. Our analytical formulas successfully compare to numerical simulations of a particular model of a branching random walk. PMID:25375474

  10. On Computational Power of Quantum Read-Once Branching Programs

    Directory of Open Access Journals (Sweden)

    Farid Ablayev

    2011-03-01

    Full Text Available In this paper we review our current results concerning the computational power of quantum read-once branching programs. First of all, based on the circuit presentation of quantum branching programs and our variant of quantum fingerprinting technique, we show that any Boolean function with linear polynomial presentation can be computed by a quantum read-once branching program using a relatively small (usually logarithmic in the size of input number of qubits. Then we show that the described class of Boolean functions is closed under the polynomial projections.

  11. Business Systems Branch Abilities, Capabilities, and Services Web Page

    Science.gov (United States)

    Cortes-Pena, Aida Yoguely

    2009-01-01

    During the INSPIRE summer internship I acted as the Business Systems Branch Capability Owner for the Kennedy Web-based Initiative for Communicating Capabilities System (KWICC), with the responsibility of creating a portal that describes the services provided by this Branch. This project will help others achieve a clear view ofthe services that the Business System Branch provides to NASA and the Kennedy Space Center. After collecting the data through the interviews with subject matter experts and the literature in Business World and other web sites I identified discrepancies, made the necessary corrections to the sites and placed the information from the report into the KWICC web page.

  12. Biology Notes.

    Science.gov (United States)

    School Science Review, 1981

    1981-01-01

    Outlines a variety of laboratory procedures, techniques, and materials including construction of a survey frame for field biology, a simple tidal system, isolation and applications of plant protoplasts, tropisms, teaching lung structure, and a key to statistical methods for biologists. (DS)

  13. (Biological dosimetry)

    Energy Technology Data Exchange (ETDEWEB)

    Preston, R.J.

    1990-12-17

    The traveler attended the 1st International Conference on Biological Dosimetry in Madrid, Spain. This conference was organized to provide information to a general audience of biologists, physicists, radiotherapists, industrial hygiene personnel and individuals from related fields on the current ability of cytogenetic analysis to provide estimates of radiation dose in cases of occupational or environmental exposure. There is a growing interest in Spain in biological dosimetry because of the increased use of radiation sources for medical and occupational uses, and with this the anticipated and actual increase in numbers of overexposure. The traveler delivered the introductory lecture on Biological Dosimetry: Mechanistic Concepts'' that was intended to provide a framework by which the more applied lectures could be interpreted in a mechanistic way. A second component of the trip was to provide advice with regard to several recent cases of overexposure that had been or were being assessed by the Radiopathology and Radiotherapy Department of the Hospital General Gregorio Maranon'' in Madrid. The traveler had provided information on several of these, and had analyzed cells from some exposed or purportedly exposed individuals. The members of the biological dosimetry group were referred to individuals at REACTS at Oak Ridge Associated Universities for advice on follow-up treatment.

  14. Biology Notes.

    Science.gov (United States)

    School Science Review, 1984

    1984-01-01

    Presents information on the teaching of nutrition (including new information relating to many current O-level syllabi) and part 16 of a reading list for A- and S-level biology. Also includes a note on using earthworms as a source of material for teaching meiosis. (JN)

  15. Southwestern desert resources

    Science.gov (United States)

    Halvorson, William L.; van Riper, Charles; Schwalbe, Cecil R.

    2010-01-01

    The southwestern deserts stretch from southeastern California to west Texas and then south to central Mexico. The landscape of this region is known as basin and range topography featuring to "sky islands" of forest rising from the desert lowlands which creates a uniquely diverse ecology. The region is further complicated by an international border, where governments have caused difficulties for many animal populations. This book puts a spotlight on individual research projects which are specific examples of work being done in the area and when they are all brought together, to shed a general light of understanding the biological and cultural resources of this vast region so that those same resources can be managed as effectively and efficiently as possible. The intent is to show that collaborative efforts among federal, state agency, university, and private sector researchers working with land managers, provides better science and better management than when scientists and land managers work independently.

  16. Effects of the structure of the branches on the two-photon absorption properties for the multi-branched molecules with nitrogen (N) as coupling center

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In order to investigate the effects of the structure of branches on the TPA properties for multi-branched molecules, the TPA cross section is calculated by using ZINDO/SOS method. The investigated mole- cules have different branches (chomorfores based on stilbene, dithienothiophene and flourene) with nitrogen(N) as coupling center. The results show that the cooperative enhancement in multi-branched molecules depends on the structures of the branches and the structures of branches play an important role in the enhancement of the TPA cross section. The designed molecules with stilbene and dithie- nothiophene as branched possess relatively larger two-photon absorption cross sections.

  17. Effects of the structure of the branches on the two-photon absorption properties for the multi-branched molecules with nitrogen (N) as coupling center

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In order to investigate the effects of the structure of branches on the TPA properties for multi-branched molecules, the TPA cross section is calculated by using ZINDO/SOS method. The investigated molecules have different branches (chomorfores based on stilbene, dithienothiophene and flourene) with nitrogen(N) as coupling center. The results show that the cooperative enhancement in multi-branched molecules depends on the structures of the branches and the structures of branches play an important role in the enhancement of the TPA cross section. The designed molecules with stilbene and dithienothiophene as branched possess relatively larger two-photon absorption cross sections.

  18. The Exploitation of Evolving Resources

    CERN Document Server

    McGlade, Jacqueline; Law, Richard

    1993-01-01

    The impact of man on the biosphere is profound. Quite apart from our capacity to destroy natural ecosystems and to drive species to extinction, we mould the evolution of the survivors by the selection pressures we apply to them. This has implications for the continued health of our natural biological resources and for the way in which we seek to optimise yield from those resources. Of these biological resources, fish stocks are particularly important to mankind as a source of protein. On a global basis, fish stocks provide the major source of protein for human consumption from natural ecosystems, amounting to some seventy million tonnes in 1970. Although fisheries management has been extensively developed over the last century, it has not hitherto considered the evolutionary consequences of fishing activity. While this omission may not have been serious in the past, the ever increasing intensity of exploitation and the deteriorating health of fish stocks has generated an urgent need for a better understanding...

  19. Critical evaluation of branch polarity and apical dominance as dictators of colony astogeny in a branching coral.

    Directory of Open Access Journals (Sweden)

    Lee Shaish

    Full Text Available The high morphological resemblance between branching corals and trees, can lead to comparative studies on pattern formation traits, best exemplified in plants and in some cnidarians. Here, 81 branches of similar size of the hermatypic coral Stylophora pistillata were lopped of three different genets, their skeletons marked with alizarin red-S, and divided haphazardly into three morphometric treatment groups: (I upright position; (II horizontal position, intact tip; and (III horizontal position, cut tip. After 1 y of in-situ growth, the 45 surviving ramets were brought to the laboratory, their tissues removed and their architectures analyzed by 22 morphological parameters (MPs. We found that within 1 y, isolated branches developed into small coral colonies by growing new branches from all branch termini, in all directions. No architectural dissimilarity was assigned among the three studied genets of treatment I colonies. However, a major architectural disparity between treatment I colonies and colonies of treatments II and III was documented as the development of mirror structures from both sides of treatments II and III settings as compared to tip-borne architectures in treatment I colonies. We did not observe apical dominance since fragments grew equally from all branch sides without documented dominant polarity along branch axis. In treatment II colonies, no MP for new branches originating either from tips or from branch bases differed significantly. In treatment III colonies, growth from the cut tip areas was significantly lower compared to the base, again, suggesting lack of apical dominance in this species. Changes in branch polarity revealed genet associated plasticity, which in one of the studied genets, led to enhanced growth. Different genets exhibited canalization flexibility of growth patterns towards either lateral growth, or branch axis extension (skeletal weight and not porosity was measured. This study revealed that colony

  20. Free compact boson on branched covering of $\\mathbb{CP}^1$ and on branched covering of the torus

    CERN Document Server

    Liu, Feihu

    2016-01-01

    We have studied free compact boson on two special kinds of Riemann surfaces: One is branched covering of $\\mathbb{CP}^1$, and the other one is branched covering of the torus. We obtain the partition function for arbitrary higher genus by directly constructing the period matrix, which can be expressed in terms of simple contour integrals. The partition function is interesting because it is related to the \\emph{product} of correlation functions of twist fields in different sectors. Also, when the branched cuts are chosen to be real, it is related to the R\\'enyi entanglement entropy of multiple intervals in a infinite (finite) system at zero (finite) temperature.

  1. SUSTAINABLE URBAN TECHNOLOGIES TEAM (URBAN WATERSHED MANAGEMENT BRANCH - WSWRD)

    Science.gov (United States)

    The National Risk Management Research Laboratory's Urban Watershed Management Branch researches, develops and evaluates technologies, practices, and systems to manage risks to human health and ecosystems from Wet Weather Flow (WWF) sources in urban watersheds. The focus is on the...

  2. Big Branch Marsh grass planting Monitoring Report 2012

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Overall, the vegetation planting in Big Branch National Wildlife Refuge was a complete success. The project site now contains greater than 50% vegetative cover of...

  3. Bounds of Deviation for Branching Chains in Random Environments

    Institute of Scientific and Technical Information of China (English)

    Wei Gang WANG

    2011-01-01

    We consider non-extinct branching processes in general random environments. Under the condition of means and second moments of each generation being bounded, we give the upper bounds and lower bounds for some form deviations of the process.

  4. Kodiak: An Implementation Framework for Branch and Bound Algorithms

    Science.gov (United States)

    Smith, Andrew P.; Munoz, Cesar A.; Narkawicz, Anthony J.; Markevicius, Mantas

    2015-01-01

    Recursive branch and bound algorithms are often used to refine and isolate solutions to several classes of global optimization problems. A rigorous computation framework for the solution of systems of equations and inequalities involving nonlinear real arithmetic over hyper-rectangular variable and parameter domains is presented. It is derived from a generic branch and bound algorithm that has been formally verified, and utilizes self-validating enclosure methods, namely interval arithmetic and, for polynomials and rational functions, Bernstein expansion. Since bounds computed by these enclosure methods are sound, this approach may be used reliably in software verification tools. Advantage is taken of the partial derivatives of the constraint functions involved in the system, firstly to reduce the branching factor by the use of bisection heuristics and secondly to permit the computation of bifurcation sets for systems of ordinary differential equations. The associated software development, Kodiak, is presented, along with examples of three different branch and bound problem types it implements.

  5. Inventory and Monitoring Plan Big Branch Marsh National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Big Branch Marsh IMP was developed according to the Inventory and Monitoring (I 1) is an operational plan for one or more refuges that clearly states I 2)...

  6. Antibiotics and renal branching morphogenesis: comparison of toxicities

    NARCIS (Netherlands)

    Bueters, R.R.G.; Kusters, L.J.; Klaasen, A.; Heuvel, L.P.W.J. van den; Schreuder, M.F.

    2014-01-01

    BACKGROUND: Many premature born neonates receive antibiotic drugs to treat infections, which are applied during active nephrogenesis. We studied the impact of clinical concentrations of gentamicin and alternatives, ceftazidime and meropenem, on ureteric branching. METHODS: Mice metanephroi were diss

  7. Branching innovation, recombinant innovation, and endogenous technological transitions

    NARCIS (Netherlands)

    Frenken, K.; Izquierdo, L.; Zeppini, P.

    2012-01-01

    We propose a model of technological transitions based on two different types of innovations. Branching innovations refer to technological improvements along a particular path, while recombinant innovations represent fusions of multiple paths. Recombinant innovations create "short-cuts" which reduce

  8. Near Critical Catalyst Reactant Branching Processes with Controlled Immigration

    CERN Document Server

    Budhiraja, Amarjit

    2012-01-01

    Near critical catalyst-reactant branching processes with controlled immigration are studied. The reactant population evolves according to a branching process whose branching rate is proportional to the total mass of the catalyst. The bulk catalyst evolution is that of a classical continuous time branching process; in addition there is a specific form of immigration. Immigration takes place exactly when the catalyst population falls below a certain threshold, in which case the population is instantaneously replenished to the threshold. Such models are motivated by problems in chemical kinetics where one wants to keep the level of a catalyst above a certain threshold in order to maintain a desired level of reaction activity. A diffusion limit theorem for the scaled processes is presented, in which the catalyst limit is described through a reflected diffusion, while the reactant limit is a diffusion with coefficients that are functions of both the reactant and the catalyst. Stochastic averaging principles under ...

  9. A Data Flow Behavior Constraints Model for Branch Decisionmaking Variables

    Directory of Open Access Journals (Sweden)

    Lu Yan

    2012-06-01

    Full Text Available In order to detect the attacks to decision-making variable, this paper presents a data flow behavior constraint model for branch decision-making variables. Our model is expanded from the common control flow model, itemphasizes on the analysis and verification about the data flow for decision-making variables, so that to ensure the branch statement can execute correctly and can also detect the attack to branch decision-making variableeasily. The constraints of our model include the collection of variables, the statements that the decision-making variables are dependent on and the data flow constraint with the use-def relation of these variables. Our experimental results indicate that it is effective in detecting the attacks to branch decision-making variables as well as the attacks to control-data.

  10. Inflorescence Architecture: The Transition from Branches to Flowers

    Science.gov (United States)

    The shapes of flowers and their organization into branching systems, called inflorescences, dictate much of plant diversity. Recent studies have identified key regulators in this diversity, revealing that the inflorescence architecture of Solanaceous species depends on sequential and temporal expres...

  11. Variation in the Branching Pattern of the Superficial Palmar Arch

    Directory of Open Access Journals (Sweden)

    Sumalatha S

    2016-05-01

    Full Text Available In this article we describe a rare variation in the superficial palmar arch (SPA encountered during routine cadaveric dissection. SPA was formed by the superficial branches of ulnar and radial arteries which provided a proper digital branch to the ulnar side of the little finger and three common palmar digital branches to the medial four digits. Additionally a first common digital artery was seen to emerge from the radial side of SPA which further divided into the arteria princeps pollicis and arteria radialis indicis. We also found a small communicating branch between the arteria princeps pollicis and the radial artery in the anatomical snuff box. Such arterial variations in the palm due to alteration in the developmental sequence remains a crucial issue in the reconstructive hand surgeries, especially while dealing with the innovative microsurgical procedures, where these varied patterns act as pivotal points around which successful results of various advanced surgical procedures revolve.

  12. Horizontal Branch stars as AmFm/HgMn stars

    CERN Document Server

    Michaud, G

    2008-01-01

    Recent observations and models for horizontal branch stars are briefly described and compared to models for AmFm stars. The limitations of those models are emphasized by a comparison to observations and models for HgMn stars.

  13. The Spectral Dimension of Non-generic Branched Polymer Ensembles

    CERN Document Server

    Correia, J D; Correia, Joao D.; Wheater, John F.

    1998-01-01

    We show that the spectral dimension on non-generic branched polymer models with susceptibility exponent $\\gamma$ is given by $2/(1+\\gamma)$. For those models with negative $\\gamma$ we find that the spectral dimension is 2.

  14. Employment of Veterans in the Federal Executive Branch

    Data.gov (United States)

    Department of Veterans Affairs — These quick facts use data from the 2011 Employment of Veterans in the Federal Executive Branch to compare Veteran employment in the Federal Government by agency,...

  15. A computable branching process for the Wigner quantum dynamics

    CERN Document Server

    Shao, Sihong

    2016-01-01

    A branching process treatment for the nonlocal Wigner pseudo-differential operator and its numerical applications in quantum dynamics is proposed and analyzed. We start from the discussion on two typical truncations of the nonlocal term, i.e., the $k$-truncated and $y$-truncated models. After introducing an auxiliary function $\\gamma(\\bm{x})$, the (truncated) Wigner equation is reformulated into the integral formulation as well as its adjoint correspondence, both of which can be regarded as the renewal-type equations and have transparent stochastic interpretation. We prove that the moment of a branching process happens to be the solution for the adjoint equation, which connects rigorously the Wigner quantum dynamics to the stochastic branching process, and thus a sound mathematical framework for the Wigner Monte Carlo methods is established. Within the framework, the branching process for the $y$-truncated model recovers the popular signed particle Monte Carlo method which needs a discretization of the moment...

  16. Resource Economics

    Science.gov (United States)

    Conrad, Jon M.

    2000-01-01

    Resource Economics is a text for students with a background in calculus, intermediate microeconomics, and a familiarity with the spreadsheet software Excel. The book covers basic concepts, shows how to set up spreadsheets to solve dynamic allocation problems, and presents economic models for fisheries, forestry, nonrenewable resources, stock pollutants, option value, and sustainable development. Within the text, numerical examples are posed and solved using Excel's Solver. These problems help make concepts operational, develop economic intuition, and serve as a bridge to the study of real-world problems of resource management. Through these examples and additional exercises at the end of Chapters 1 to 8, students can make dynamic models operational, develop their economic intuition, and learn how to set up spreadsheets for the simulation of optimization of resource and environmental systems. Book is unique in its use of spreadsheet software (Excel) to solve dynamic allocation problems Conrad is co-author of a previous book for the Press on the subject for graduate students Approach is extremely student-friendly; gives students the tools to apply research results to actual environmental issues

  17. Computer simulations of randomly branching polymers: annealed versus quenched branching structures

    Science.gov (United States)

    Rosa, Angelo; Everaers, Ralf

    2016-08-01

    We present computer simulations of three systems of randomly branching polymers in d = 3 dimensions: ideal trees and self-avoiding trees with annealed and quenched connectivities. In all cases, we performed a detailed analysis of trees connectivities, spatial conformations and statistical properties of linear paths on trees, and compare the results to the corresponding predictions of Flory theory. We confirm that, overall, the theory predicts correctly that trees with quenched ideal connectivity exhibit less overall swelling in good solvent than corresponding trees with annealed connectivity even though they are more strongly stretched on the path level. At the same time, we emphasize the inadequacy of the Flory theory in predicting the behaviour of other, and equally relevant, observables like contact probabilities between tree nodes. We show, then, that contact probabilities can be aptly characterized by introducing a novel critical exponent, {θ }{path}, which accounts for how they decay as a function of the node-to-node path distance on the tree.

  18. Toward Network Biology in E. coli Cell.

    Science.gov (United States)

    Mori, Hirotada; Takeuchi, Rikiya; Otsuka, Yuta; Bowden, Steven; Yokoyama, Katsushi; Muto, Ai; Libourel, Igor; Wanner, Barry L

    2015-01-01

    E. coli has been a critically important model research organism for more than 50 years, particularly in molecular biology. In 1997, the E. coli draft genome sequence was published. Post-genomic techniques and resources were then developed that allowed E. coli to become a model organism for systems biology. Progress made since publication of the E. coli genome sequence will be summarized.

  19. Branch retinal vein occlusion associated with quetiapine fumarate

    Directory of Open Access Journals (Sweden)

    Siang Lim

    2011-08-01

    Full Text Available Abstract Background To report a case of branch retinal vein occlusion in a young adult with bipolar mood disorder treated with quetiapine fumarate. Case Presentation A 29 years old gentleman who was taking quetiapine fumarate for 3 years for bipolar mood disorder, presented with sudden vision loss. He was found to have a superior temporal branch retinal vein occlusion associated with hypercholesterolemia. Conclusion Atypical antipsychotic drugs have metabolic side effects which require regular monitoring and prompt treatment.

  20. Size-exclusion chromatography (SEC) of branched polymers and polysaccharides

    OpenAIRE

    Gaborieau, Marianne; Castignolles, Patrice

    2010-01-01

    Branched polymers are among the most important polymers, ranging from polyolefins to polysaccharides. Branching plays a key role in the chain dynamics. It is thus very important for application properties such as mechanical and adhesive properties and digestibility. It also plays a key role in viscous properties, and thus in the mechanism of the separation of these polymers in size-exclusion chromatography (SEC). Critically reviewing the literature, particularly on SEC of polyolefins, polyacr...