WorldWideScience

Sample records for biological research project

  1. Biologically Weighted Quantities in Radiotherapy: an EMRP Joint Research Project

    Directory of Open Access Journals (Sweden)

    Rabus Hans

    2014-01-01

    Full Text Available Funded within the European Metrology Research Programme (EMRP [1], the joint research projectBiologically weighted quantities in radiotherapy” (BioQuaRT [2] aims to develop measurement and simulation techniques for determining the physical properties of ionising particle tracks on different length scales (about 2 nm to 10 μm, and to investigate the correlation of these track structure characteristics with the biological effects of radiation at the cellular level. Work package 1 develops micro-calorimeter prototypes for the direct measurement of lineal energy and will characterise their response for different ion beams by experiment and modelling. Work package 2 develops techniques to measure particle track structure on different length scales in the nanometre range as well as a measurement device integrating a silicon microdosimeter and a nanodosimeter. Work package 3 investigates the indirect effects of radiation based on probes for quantifying particular radical and reactive oxygen species (ROS. Work package 4 focuses on the biological aspects of radiation damage and will produce data on initial DNA damage and late effects for radiotherapy beams of different qualities. Work package 5 provides evaluated data sets of DNA cross-sections and develops a multi-scale model to address microscopic and nanometric track structure properties. The project consortium includes three linked researchers holding so-called Researcher Excellence Grants, who carry out ancillary investigations such as developing and benchmarking a new biophysical model for induction of early radiation damage and developing methods for the translation of quantities derived from particle track structure to clinical applications in ion beam therapy.

  2. [New materia medica project: synthetic biology based bioactive metabolites research in medicinal plant].

    Science.gov (United States)

    Wang, Yong

    2017-03-25

    In the last decade, synthetic biology research has been gradually transited from monocellular parts or devices toward more complex multicellular systems. The emerging plant synthetic biology is regarded as the "next chapter" of synthetic biology. The complex and diverse plant metabolism as the entry point, plant synthetic biology research not only helps us understand how real life is working, but also facilitates us to learn how to design and construct more complex artificial life. Bioactive compounds innovation and large-scale production are expected to be breakthrough with the redesigned plant metabolism as well. In this review, we discuss the research progress in plant synthetic biology and propose the new materia medica project to lift the level of traditional Chinese herbal medicine research.

  3. Team Research at the Biology-Mathematics Interface: Project Management Perspectives

    Science.gov (United States)

    Milton, John G.; Radunskaya, Ami E.; Lee, Arthur H.; de Pillis, Lisette G.; Bartlett, Diana F.

    2010-01-01

    The success of interdisciplinary research teams depends largely upon skills related to team performance. We evaluated student and team performance for undergraduate biology and mathematics students who participated in summer research projects conducted in off-campus laboratories. The student teams were composed of a student with a mathematics…

  4. Team research at the biology-mathematics interface: project management perspectives.

    Science.gov (United States)

    Milton, John G; Radunskaya, Ami E; Lee, Arthur H; de Pillis, Lisette G; Bartlett, Diana F

    2010-01-01

    The success of interdisciplinary research teams depends largely upon skills related to team performance. We evaluated student and team performance for undergraduate biology and mathematics students who participated in summer research projects conducted in off-campus laboratories. The student teams were composed of a student with a mathematics background and an experimentally oriented biology student. The team mentors typically ranked the students' performance very good to excellent over a range of attributes that included creativity and ability to conduct independent research. However, the research teams experienced problems meeting prespecified deadlines due to poor time and project management skills. Because time and project management skills can be readily taught and moreover typically reflect good research practices, simple modifications should be made to undergraduate curricula so that the promise of initiatives, such as MATH-BIO 2010, can be implemented.

  5. Research Projects for Interrogations of Biological Systems: Training for the Development of Novel Radiotracers

    Energy Technology Data Exchange (ETDEWEB)

    Jurisson, Silvia S. [Univ. of Missouri, Columbia, MO (United States); Lever, Susan Z. [Univ. of Missouri, Columbia, MO (United States); Robertson, J. David [Univ. of Missouri, Columbia, MO (United States)

    2016-10-04

    This grant was situated at the University of Missouri to train Ph.D. scientists in radiochemistry and synthetic chemistry in conjunction with Faculty from the Interdisciplinary Plant Group, Division of Biological Sciences, the MU Research Reactor Center, Molecular Biology and the Radiopharmaceutical Sciences Institute. This project was collaborative with Brookhaven National Laboratory (Richard Ferrieri, PI). Projects for the Ph.D. candidates included novel probe development for peptides, nucleosides, small molecules or radiometals, the direct use of radiometals as probes, or nuclear techniques for analysis. The projects for the postdoctoral fellow involved synthetic chemistry for the preparation of precursors for novel tracers that will be radiolabeled with 18F or other appropriate radionuclides. The skill sets of our team members allowed us to prepare probes with positron or single photon emitters, as well as ones that are dual-labeled (fluorescent and radiolabeled). We focused our technical advances to those that will be broadly applicable to any research field.

  6. Research Projects for Interrogations of Biological Systems: Training for the Development of Novel Radiotracers

    International Nuclear Information System (INIS)

    Jurisson, Silvia S.; Lever, Susan Z.; Robertson, J. David

    2016-01-01

    This grant was situated at the University of Missouri to train Ph.D. scientists in radiochemistry and synthetic chemistry in conjunction with Faculty from the Interdisciplinary Plant Group, Division of Biological Sciences, the MU Research Reactor Center, Molecular Biology and the Radiopharmaceutical Sciences Institute. This project was collaborative with Brookhaven National Laboratory (Richard Ferrieri, PI). Projects for the Ph.D. candidates included novel probe development for peptides, nucleosides, small molecules or radiometals, the direct use of radiometals as probes, or nuclear techniques for analysis. The projects for the postdoctoral fellow involved synthetic chemistry for the preparation of precursors for novel tracers that will be radiolabeled with "1"8F or other appropriate radionuclides. The skill sets of our team members allowed us to prepare probes with positron or single photon emitters, as well as ones that are dual-labeled (fluorescent and radiolabeled). We focused our technical advances to those that will be broadly applicable to any research field.

  7. Connecting biology and organic chemistry introductory laboratory courses through a collaborative research project.

    Science.gov (United States)

    Boltax, Ariana L; Armanious, Stephanie; Kosinski-Collins, Melissa S; Pontrello, Jason K

    2015-01-01

    Modern research often requires collaboration of experts in fields, such as math, chemistry, biology, physics, and computer science to develop unique solutions to common problems. Traditional introductory undergraduate laboratory curricula in the sciences often do not emphasize connections possible between the various disciplines. We designed an interdisciplinary, medically relevant, project intended to help students see connections between chemistry and biology. Second term organic chemistry laboratory students designed and synthesized potential polymer inhibitors or inducers of polyglutamine protein aggregation. The use of novel target compounds added the uncertainty of scientific research to the project. Biology laboratory students then tested the novel potential pharmaceuticals in Huntington's disease model assays, using in vitro polyglutamine peptide aggregation and in vivo lethality studies in Drosophila. Students read articles from the primary literature describing the system from both chemical and biological perspectives. Assessment revealed that students emerged from both courses with a deeper understanding of the interdisciplinary nature of biology and chemistry and a heightened interest in basic research. The design of this collaborative project for introductory biology and organic chemistry labs demonstrated how the local interests and expertise at a university can be drawn from to create an effective way to integrate these introductory courses. Rather than simply presenting a series of experiments to be replicated, we hope that our efforts will inspire other scientists to think about how some aspect of authentic work can be brought into their own courses, and we also welcome additional collaborations to extend the scope of the scientific exploration. © 2015 The International Union of Biochemistry and Molecular Biology.

  8. Learning how scientists work: experiential research projects to promote cell biology learning and scientific process skills.

    Science.gov (United States)

    DebBurman, Shubhik K

    2002-01-01

    Facilitating not only the mastery of sophisticated subject matter, but also the development of process skills is an ongoing challenge in teaching any introductory undergraduate course. To accomplish this goal in a sophomore-level introductory cell biology course, I require students to work in groups and complete several mock experiential research projects that imitate the professional activities of the scientific community. I designed these projects as a way to promote process skill development within content-rich pedagogy and to connect text-based and laboratory-based learning with the world of contemporary research. First, students become familiar with one primary article from a leading peer-reviewed journal, which they discuss by means of PowerPoint-based journal clubs and journalism reports highlighting public relevance. Second, relying mostly on primary articles, they investigate the molecular basis of a disease, compose reviews for an in-house journal, and present seminars in a public symposium. Last, students author primary articles detailing investigative experiments conducted in the lab. This curriculum has been successful in both quarter-based and semester-based institutions. Student attitudes toward their learning were assessed quantitatively with course surveys. Students consistently reported that these projects significantly lowered barriers to primary literature, improved research-associated skills, strengthened traditional pedagogy, and helped accomplish course objectives. Such approaches are widely suited for instructors seeking to integrate process with content in their courses.

  9. S.A.P. Students Adopt Plants: A Curriculum Guide for Independent Research Projects in High School Biology.

    Science.gov (United States)

    Wilkinson, Gayle A.

    This curriculum guide begins with classroom and text study of plants and develops into an individual research project that continues throughout the school year outside the regular biology or botany teaching plan and text. The project uses about one class period every 2 weeks for group discussions, evaluations, and suggestions for the individual…

  10. Overview of research in radiation biology and protective measures in the Manhattan Project during the war years, 1942-1946

    International Nuclear Information System (INIS)

    Friedell, H.L.

    The objecitve was to present a cohesive view of the general biological research program associated with the Manhattan Project. The material is arrangd in chronological order. Each of the major research sites is identified and the general nature of their research program indicated. A section is devoted to the question of the various radiation limits which were used in the operational approach to hazard controls

  11. Integration of a zebrafish research project into a molecular biology course to support critical thinking and course content goals.

    Science.gov (United States)

    Felzien, Lisa K

    2016-11-12

    Engaging undergraduates in research is essential for teaching them to think like scientists, and it has become a desired component of classroom and laboratory instruction. Research projects that span an entire semester expose students to a variety of concepts and techniques and allow students to use experiments to learn scientific principles, understand why specific techniques are applicable, critically analyze varied data, and examine how experimentation leads to acquiring knowledge. To provide an experience with these features, a semester long research project was integrated into a combined lecture and laboratory course, Molecular Biology. The project utilized the zebrafish model to examine gene expression during embryonic development and required students to develop and test hypotheses about the timing of expression of previously uncharacterized genes. The main goals for the project were to provide opportunities for students to develop critical thinking skills required for conducting research and to support the content goals of the course. To determine whether these goals were met, student performance on the steps of the project and related pre-test and post-test questions was examined. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):565-573, 2016. © 2016 The International Union of Biochemistry and Molecular Biology.

  12. Connecting Biology and Organic Chemistry Introductory Laboratory Courses through a Collaborative Research Project

    Science.gov (United States)

    Boltax, Ariana L.; Armanious, Stephanie; Kosinski-Collins, Melissa S.; Pontrello, Jason K.

    2015-01-01

    Modern research often requires collaboration of experts in fields, such as math, chemistry, biology, physics, and computer science to develop unique solutions to common problems. Traditional introductory undergraduate laboratory curricula in the sciences often do not emphasize connections possible between the various disciplines. We designed an…

  13. [Review and analysis of transplant biological research projects funded by National Natural Science Foundation of China].

    Science.gov (United States)

    Gong, Weihua; Sun, Ruijuan; Dong, Erdan

    2015-08-01

    To study the funding and achievements in the field of organ transplantation support by the National Natural Science Foundation of China (NSFC). A search of NSFC database was made by using the key word "transplantation" and excluding "bone marrow transplantation" for the projects funded between 1988 and 2013. SCI indexed publications that marked with NSFC project number were collected by searching each grant number in the database of the Web of Science. Six hundreds fifty-five projects were identified and received about 220 million yuan in grant funding. These funded research projects were distributed among 25 provinces and autonomous regions, however, which were mainly in the developed coastal areas; of them, 43 (6.56%) projects were granted in xenotransplantation and 17 projects (2.60%) were funded in the field of traditional Chinese medicine-related organ transplantation; Transplantation on blood vessels, heart, kidney, liver, lung, small intestine, pancreatic, cornea, trachea, skin, etc. were primarily performed in research. Nine hundreds and sixty-one SCI-indexed publications were achieved. Magnitude and intensity of NSFC funding, output of SCI publications have been increasing, suggesting that NSFC positively promotes the development of organ transplantation. Although a great progress of transplantation has been made, basic and translational studies should be vigorously strengthened.

  14. Space Synthetic Biology Project

    Science.gov (United States)

    Howard, David; Roman, Monsi; Mansell, James (Matt)

    2015-01-01

    Synthetic biology is an effort to make genetic engineering more useful by standardizing sections of genetic code. By standardizing genetic components, biological engineering will become much more similar to traditional fields of engineering, in which well-defined components and subsystems are readily available in markets. Specifications of the behavior of those components and subsystems can be used to model a system which incorporates them. Then, the behavior of the novel system can be simulated and optimized. Finally, the components and subsystems can be purchased and assembled to create the optimized system, which most often will exhibit behavior similar to that indicated by the model. The Space Synthetic Biology project began in 2012 as a multi-Center effort. The purpose of this project was to harness Synthetic Biology principals to enable NASA's missions. A central target for application was to Environmental Control & Life Support (ECLS). Engineers from NASA Marshall Space Flight Center's (MSFC's) ECLS Systems Development Branch (ES62) were brought into the project to contribute expertise in operational ECLS systems. Project lead scientists chose to pursue the development of bioelectrochemical technologies to spacecraft life support. Therefore, the ECLS element of the project became essentially an effort to develop a bioelectrochemical ECLS subsystem. Bioelectrochemical systems exploit the ability of many microorganisms to drive their metabolisms by direct or indirect utilization of electrical potential gradients. Whereas many microorganisms are capable of deriving the energy required for the processes of interest (such as carbon dioxide (CO2) fixation) from sunlight, it is believed that subsystems utilizing electrotrophs will exhibit smaller mass, volume, and power requirements than those that derive their energy from sunlight. In the first 2 years of the project, MSFC personnel conducted modeling, simulation, and conceptual design efforts to assist the

  15. Conclusions and perspectives: Perspectives for future research-and-development projects on biological

    NARCIS (Netherlands)

    Nicot, P.C.; Blum, B.; Köhl, J.; Ruocco, M.

    2011-01-01

    The review of published scientific literature on the biological control of selected pests and diseases has lead to the identification of clear knowledge gaps highlighted in previous chapters. Further bottlenecks were revealed by seeking the possible reasons for the striking discrepancy between the

  16. Space biology research development

    Science.gov (United States)

    Bonting, Sjoerd L.

    1993-01-01

    The purpose of the Search for Extraterrestrial Intelligence (SETI) Institute is to conduct and promote research related activities regarding the search for extraterrestrial life, particularly intelligent life. Such research encompasses the broad discipline of 'Life in the Universe', including all scientific and technological aspects of astronomy and the planetary sciences, chemical evolution, the origin of life, biological evolution, and cultural evolution. The primary purpose was to provide funding for the Principal Investigator to collaborate with the personnel of the SETI Institute and the NASA-Ames Research center in order to plan and develop space biology research on and in connection with Space Station Freedom; to promote cooperation with the international partners in the space station; to conduct a study on the use of biosensors in space biology research and life support system operation; and to promote space biology research through the initiation of an annual publication 'Advances in Space Biology and Medicine'.

  17. Plant Biology Science Projects.

    Science.gov (United States)

    Hershey, David R.

    This book contains science projects about seed plants that deal with plant physiology, plant ecology, and plant agriculture. Each of the projects includes a step-by-step experiment followed by suggestions for further investigations. Chapters include: (1) "Bean Seed Imbibition"; (2) "Germination Percentages of Different Types of Seeds"; (3)…

  18. Some perspectives on research into the biological response to non-ionizing electromagnetic radiation. [relation to SETI, SPS, and other government projects

    Science.gov (United States)

    Sharp, J. C.

    1979-01-01

    Research on the biological effects of RF radiation in the United States has undergone a series of swings during the last three decades. The resurgence of research during the past decade is examined in the light of two projects: the proposed Space Power Station and SETI.

  19. Including a Service Learning Educational Research Project in a Biology Course-I: Assessing Community Awareness of Childhood Lead Poisoning

    Science.gov (United States)

    Abu-Shakra, Amal; Saliim, Eric

    2012-01-01

    A university course project was developed and implemented in a biology course, focusing on environmental problems, to assess community awareness of childhood lead poisoning. A set of 385 questionnaires was generated and distributed in an urban community in North Carolina, USA. The completed questionnaires were sorted first into yes and no sets…

  20. Publications of the planetary biology program for 1975: A special bibliography. [on NASA programs and research projects on extraterrestrial life

    Science.gov (United States)

    Souza, K. A. (Compiler); Young, R. S. (Compiler)

    1976-01-01

    The Planetary Biology Program of the National Aeronautics and Space Administration is the first and only integrated program to methodically investigate the planetary events which may have been responsible for, or related to, the origin, evolution, and distribution of life in the universe. Research supported by this program is divided into the seven areas listed below: (1) chemical evolution, (2) organic geochemistry, (3) life detection, (4) biological adaptation, (5) bioinstrumentation, (6) planetary environments, and (7) origin of life. The arrangement of references in this bibliography follows the division of research described above. Articles are listed alphabetically by author under the research area with which they are most closely related. Only those publications which resulted from research supported by the Planetary Biology Program and which bear a 1975 publication date have been included. Abstracts and theses are not included because of the preliminary and abbreviated nature of the former and the frequent difficulty of obtaining the latter.

  1. TP Atlas: integration and dissemination of advances in Targeted Proteins Research Program (TPRP)-structural biology project phase II in Japan.

    Science.gov (United States)

    Iwayanagi, Takao; Miyamoto, Sei; Konno, Takeshi; Mizutani, Hisashi; Hirai, Tomohiro; Shigemoto, Yasumasa; Gojobori, Takashi; Sugawara, Hideaki

    2012-09-01

    The Targeted Proteins Research Program (TPRP) promoted by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan is the phase II of structural biology project (2007-2011) following the Protein 3000 Project (2002-2006) in Japan. While the phase I Protein 3000 Project put partial emphasis on the construction and maintenance of pipelines for structural analyses, the TPRP is dedicated to revealing the structures and functions of the targeted proteins that have great importance in both basic research and industrial applications. To pursue this objective, 35 Targeted Proteins (TP) Projects selected in the three areas of fundamental biology, medicine and pharmacology, and food and environment are tightly collaborated with 10 Advanced Technology (AT) Projects in the four fields of protein production, structural analyses, chemical library and screening, and information platform. Here, the outlines and achievements of the 35 TP Projects are summarized in the system named TP Atlas. Progress in the diversified areas is described in the modules of Graphical Summary, General Summary, Tabular Summary, and Structure Gallery of the TP Atlas in the standard and unified format. Advances in TP Projects owing to novel technologies stemmed from AT Projects and collaborative research among TP Projects are illustrated as a hallmark of the Program. The TP Atlas can be accessed at http://net.genes.nig.ac.jp/tpatlas/index_e.html .

  2. Basic research projects

    International Nuclear Information System (INIS)

    1979-04-01

    The research programs under the cognizance of the Office of Energy Research (OER) are directed toward discovery of natural laws and new knowledge, and to improved understanding of the physical and biological sciences as related to the development, use, and control of energy. The ultimate goal is to develop a scientific underlay for the overall DOE effort and the fundamental principles of natural phenomena so that these phenomena may be understood, and new principles, formulated. The DOE-OER outlay activities include three major programs: High Energy Physics, Nuclear Physics, and Basic Energy Sciences. Taken together, these programs represent some 30 percent of the Nation's Federal support of basic research in the energy sciences. The research activities of OER involve more than 6,000 scientists and engineers working in some 17 major Federal Research Centers and at more than 135 different universities and industrial firms throughout the United States. Contract holders in the areas of high-energy physics, nuclear physics, materials sciences, nuclear science, chemical sciences, engineering, mathematics geosciences, advanced energy projects, and biological energy research are listed. Funding trends for recent years are outlined

  3. Biologically inspired technologies in NASA's morphing project

    Science.gov (United States)

    McGowan, Anna-Maria R.; Cox, David E.; Lazos, Barry S.; Waszak, Martin R.; Raney, David L.; Siochi, Emilie J.; Pao, S. Paul

    2003-07-01

    For centuries, biology has provided fertile ground for hypothesis, discovery, and inspiration. Time-tested methods used in nature are being used as a basis for several research studies conducted at the NASA Langley Research Center as a part of Morphing Project, which develops and assesses breakthrough vehicle technologies. These studies range from low drag airfoil design guided by marine and avian morphologies to soaring techniques inspired by birds and the study of small flexible wing vehicles. Biology often suggests unconventional yet effective approaches such as non-planar wings, dynamic soaring, exploiting aeroelastic effects, collaborative control, flapping, and fibrous active materials. These approaches and other novel technologies for future flight vehicles are being studied in NASA's Morphing Project. This paper will discuss recent findings in the aeronautics-based, biologically-inspired research in the project.

  4. A Study on Evaluation of the Biology Projects Submitted to the TUBITAK Secondary Education Research Projects Contest from the Bursa Region

    Science.gov (United States)

    Zeren Özer, Dilek; Güngör, Sema Nur; Özkan, Muhlis

    2015-01-01

    This study evaluates, through the employment of scientific methods and techniques, a total of 107 Biology projects submitted by secondary education students to the Bursa Region Coordinatorship of TUBITAK (a region which encompasses the municipalities of Afyonkarahisar, Balikesir, Bilecik, Canakkale, Eskisehir, Kutahya, and Yalova). The projects…

  5. Integration of a Zebrafish Research Project into a Molecular Biology Course to Support Critical Thinking and Course Content Goals

    Science.gov (United States)

    Felzien, Lisa K.

    2016-01-01

    Engaging undergraduates in research is essential for teaching them to think like scientists, and it has become a desired component of classroom and laboratory instruction. Research projects that span an entire semester expose students to a variety of concepts and techniques and allow students to use experiments to learn scientific principles,…

  6. PAC research in biology

    Energy Technology Data Exchange (ETDEWEB)

    Chain, C. Y., E-mail: yamil@fisica.unlp.edu.ar [Universidad Nacional de La Plata, IFLP (Argentina); Ceolin, M. [Instituto de Investigaciones Fisicoquimicas Teoricas y Aplicadas, Dto de Quimica, Fac. Cs. Exactas, UNLP (Argentina); Pasquevich, A. F. [Universidad Nacional de La Plata, IFLP (Argentina)

    2008-01-15

    In this paper possible applications of the Perturbed Angular Correlations (PAC) technique in Biology are considered. Previous PAC experiments in biology are globally analyzed. All the work that appears in the literature has been grouped in a few research lines, just to make the analysis and discussion easy. The commonly used radioactive probes are listed and the experimental difficulties are analyzed. We also report applications of {sup 181}Hf and {sup 111}In isotopes in life sciences other than their use in PAC. The possibility of extending these studies using the PAC technique is discussed.

  7. Life sciences space biology project planning

    Science.gov (United States)

    Primeaux, G.; Newkirk, K.; Miller, L.; Lewis, G.; Michaud, R.

    1988-01-01

    The Life Sciences Space Biology (LSSB) research will explore the effect of microgravity on humans, including the physiological, clinical, and sociological implications of space flight and the readaptations upon return to earth. Physiological anomalies from past U.S. space flights will be used in planning the LSSB project.The planning effort integrates science and engineering. Other goals of the LSSB project include the provision of macroscopic view of the earth's biosphere, and the development of spinoff technology for application on earth.

  8. The Current Status of the Space Station Biological Research Project: a Core Facility Enabling Multi-Generational Studies under Slectable Gravity Levels

    Science.gov (United States)

    Santos, O.

    2002-01-01

    The Space Station Biological Research Project (SSBRP) has developed a new plan which greatly reduces the development costs required to complete the facility. This new plan retains core capabilities while allowing for future growth. The most important piece of equipment required for quality biological research, the 2.5 meter diameter centrifuge capable of accommodating research specimen habitats at simulated gravity levels ranging from microgravity to 2.0 g, is being developed by NASDA, the Japanese space agency, for the SSBRP. This is scheduled for flight to the ISS in 2007. The project is also developing a multi-purpose incubator, an automated cell culture unit, and two microgravity habitat holding racks, currently scheduled for launch in 2005. In addition the Canadian Space Agency is developing for the project an insect habitat, which houses Drosophila melanogaster, and provides an internal centrifuge for 1 g controls. NASDA is also developing for the project a glovebox for the contained manipulation and analysis of biological specimens, scheduled for launch in 2006. This core facility will allow for experimentation on small plants (Arabidopsis species), nematode worms (C. elegans), fruit flies (Drosophila melanogaster), and a variety of microorganisms, bacteria, yeast, and mammalian cells. We propose a plan for early utilization which focuses on surveys of changes in gene expression and protein structure due to the space flight environment. In the future, the project is looking to continue development of a rodent habitat and a plant habitat that can be accommodated on the 2.5 meter centrifuge. By utilizing the early phases of the ISS to broadly answer what changes occur at the genetic and protein level of cells and organisms exposed to the ISS low earth orbit environment, we can generate interest for future experiments when the ISS capabilities allow for direct manipulation and intervention of experiments. The ISS continues to hold promise for high quality, long

  9. Space Station Biological Research Project (SSBRP) Cell Culture Unit (CCU) and incubator for International Space Station (ISS) cell culture experiments

    Science.gov (United States)

    Vandendriesche, Donald; Parrish, Joseph; Kirven-Brooks, Melissa; Fahlen, Thomas; Larenas, Patricia; Havens, Cindy; Nakamura, Gail; Sun, Liping; Krebs, Chris; de Luis, Javier; hide

    2004-01-01

    The CCU and Incubator are habitats under development by SSBRP for gravitational biology research on ISS. They will accommodate multiple specimen types and reside in either Habitat Holding Racks, or the Centrifuge Rotor, which provides selectable gravity levels of up to 2 g. The CCU can support multiple Cell Specimen Chambers, CSCs (18, 9 or 6 CSCs; 3, 10 or 30 mL in volume, respectively). CSCs are temperature controlled from 4-39 degrees C, with heat shock to 45 degrees C. CCU provides automated nutrient supply, magnetic stirring, pH/O2 monitoring, gas supply, specimen lighting, and video microscopy. Sixty sample containers holding up to 2 mL each, stored at 4-39 degrees C, are available for automated cell sampling, subculture, and injection of additives and fixatives. CSCs, sample containers, and fresh/spent media bags are crew-replaceable for long-term experiments. The Incubator provides a 4-45 degrees C controlled environment for life science experiments or storage of experimental reagents. Specimen containers and experiment unique equipment are experimenter-provided. The Specimen Chamber exchanges air with ISS cabin and has 18.8 liters of usable volume that can accommodate six trays and the following instrumentation: five relocatable thermometers, two 60 W power outlets, four analog ports, and one each relative humidity sensor, video port, ethernet port and digital input/output port.

  10. Student Research Projects

    Science.gov (United States)

    Yeske, Lanny A.

    1998-01-01

    Numerous FY1998 student research projects were sponsored by the Mississippi State University Center for Air Sea Technology. This technical note describes these projects which include research on: (1) Graphical User Interfaces, (2) Master Environmental Library, (3) Database Management Systems, (4) Naval Interactive Data Analysis System, (5) Relocatable Modeling Environment, (6) Tidal Models, (7) Book Inventories, (8) System Analysis, (9) World Wide Web Development, (10) Virtual Data Warehouse, (11) Enterprise Information Explorer, (12) Equipment Inventories, (13) COADS, and (14) JavaScript Technology.

  11. Tumor Biology and Microenvironment Research

    Science.gov (United States)

    Part of NCI's Division of Cancer Biology's research portfolio, research in this area seeks to understand the role of tumor cells and the tumor microenvironment (TME) in driving cancer initiation, progression, maintenance and recurrence.

  12. SIMS applications in biological research

    International Nuclear Information System (INIS)

    Prince, K.E.; Burke, P.T.; Kelly, I.J.

    2000-01-01

    Full text: SIMS has been utilised as a tool for biological research since the early 1970's. SIMS' abilities in isotopic detection with high sensitivity, imaging capabilities at a subcellular level, and the possibility of molecular imaging have been the main areas of interest for biological development. However, whilst hundreds of instruments are available in industrial and university laboratories for semiconductor and materials analysis, only a handful successfully perform biological research. For this reason there is generally a lack of awareness of SIMS by the biological community. Biological SIMS analysis requires a working knowledge of both biology and SIMS. Sample preparation is a critical and time consuming prerequisite for any successful biological SIMS study. In addition, for quantification to be possible a homogeneous, matrix matched standard must be available. Once these difficulties are more widely understood and overcome there will be a greater motivation for the biological community to embrace SIMS as a unique tool in their research. This paper provides an overview of some of the more successful biological SIMS application areas internationally, and summarises the types of biological SIMS requests received by ANSTO

  13. VT Biodiversity Project - Biological Hotspots

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This dataset is the result of an effort to map biological "hotspots" in Vermont based on the "element occurrences" in the Nongame and Natural...

  14. Biological Defense Research Program

    Science.gov (United States)

    1989-04-01

    difference between life and death. Some recent examples are: BDRP developed VEE vaccine used in Central America, Mexico , and Texas (1969- 1971.) and Rift...Complex, is adn area owned by the Bureau of Land Management, which is available for grazina, and with specific permission, for use by DPG. 2.3...2.01 A Large European Laboratory, 1944-1950 50.00 Tuberculosis Laboratory 4 Technicians, Canada, 1947-1954 19.00 Research Institutes, 1930-1950 4.10

  15. Catalogue of research projects

    International Nuclear Information System (INIS)

    Skarp, K.

    1993-01-01

    The Centre for Materials Science serves as an umbrella for organizations involved in materials research at the two Universities and at certain branch institutes in the Gothenburg region. The general goal of the Centre is to promote materials research among the member organizations and to provide a link to industry and to the society at large. Members of the Centre work on most aspects of modern materials research, ranging from single-atom manipulation and theoretical simulations to biomaterials and production engineering. In order to give a presentation of the members and their research, the Centre produces an inventory of materials research projects approximately every four years. The 1993 issue is somewhat more extensive than previous editions, detailing e.g. also scientific equipment and listing work published during the past four years. The register covers the following main headings: General materials and surface science; Materials chemistry; Polymers and fibres; Biomaterials; Clusters and fine particles; Electronic and opto-electronic materials; Superconductors and nanometer structures; Ceramics; Metals; Building materials; Production and materials processing

  16. Biologically Inspired Micro-Flight Research

    Science.gov (United States)

    Raney, David L.; Waszak, Martin R.

    2003-01-01

    Natural fliers demonstrate a diverse array of flight capabilities, many of which are poorly understood. NASA has established a research project to explore and exploit flight technologies inspired by biological systems. One part of this project focuses on dynamic modeling and control of micro aerial vehicles that incorporate flexible wing structures inspired by natural fliers such as insects, hummingbirds and bats. With a vast number of potential civil and military applications, micro aerial vehicles represent an emerging sector of the aerospace market. This paper describes an ongoing research activity in which mechanization and control concepts for biologically inspired micro aerial vehicles are being explored. Research activities focusing on a flexible fixed- wing micro aerial vehicle design and a flapping-based micro aerial vehicle concept are presented.

  17. FY 2000 research cooperation project on the research cooperation for the preservation, sustainable utilization, etc. of the biological diversification. Follow-up; 2000 nendo kenkyu kyoryoku jigyo. Seibutsu tayosei hozen to zizokuteki riyo to ni kansuru kenkyu kyoryoku (Follow up)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of contributing to developing countries' preserving biological resources in the tropical region, etc. and making the sustainable utilization of biological resources using biotechnology, etc. possible, research cooperation for strengthening the base of international research cooperation was given, and the FY 2000 results were outlined. In this fiscal year, visits were paid to research institutes in Indonesia, Thailand and Malaysia for survey of the present situation. In Indonesia, conducted were the study of information system and culture collection, study of plant utilization technology, study of utilization technology of bacteria, etc., and improvement in personnel, facilities and maintenance management power of research cooperation institutes was confirmed. In Thailand and Malaysia, conducted were the study of information system and culture collection, study of rule making of the access profit distribution to genetic resource, and management of the biological resource sampled and study of the route to the industrial utilization. Taking advantage of this project, the contract for the genetic resource search for commercial purpose was agreed between a Japanese company and a Malaysian institute. (NEDO)

  18. Evolutionary Biology Research in India

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 10. Evolutionary Biology Research in India. Information and Announcements Volume 5 Issue 10 October 2000 pp 102-104. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/005/10/0102-0104 ...

  19. [Biological research and security institutes].

    Science.gov (United States)

    Darsie, G; Falczuk, A J; Bergmann, I E

    2006-04-01

    The threat of using biological material for ago-bioterrorist ends has risen in recent years, which means that research and diagnostic laboratories, biological agent banks and other institutions authorised to carry out scientific activities have had to implement biosafety and biosecurity measures to counter the threat, while carrying out activities to help prevent and monitor the accidental or intentional introduction of exotic animal diseases. This article briefly sets outthe basic components of biosafety and biosecurity, as well as recommendations on organisational strategies to consider in laboratories that support agro-bioterrorist surveillance and prevention programs.

  20. Development trend of radiation biology research-systems radiation biology

    International Nuclear Information System (INIS)

    Min Rui

    2010-01-01

    Radiation biology research has past 80 years. We have known much more about fundamentals, processes and results of biology effects induced by radiation and various factors that influence biology effects wide and deep, however many old and new scientific problems occurring in the field of radiation biology research remain to be illustrated. To explore and figure these scientific problems need systemic concept, methods and multi dimension view on the base of considerations of complexity of biology system, diversity of biology response, temporal and spatial process of biological effects during occurrence, and complex feed back network of biological regulations. (authors)

  1. National register of research projects

    Energy Technology Data Exchange (ETDEWEB)

    1985-03-01

    This Register is intended to serve as a source of information on research which is being conducted in all fields (both natural and human sciences) in the Republic of South Africa. New research projects commenced during 1983 or 1984, and significantly changed research projects, as well as project that were completed or terminated during this period, on which information was received by the compilers before December 1984, are included, with the exception of confidential projects.

  2. Review of domestic radiation biology research

    International Nuclear Information System (INIS)

    Zheng Chun; Song Lingli; Ai Zihui

    2011-01-01

    Radiation biology research in China during the past ten years are reviewed. It should be noticed that radiation-biology should focus on microdosimetry, microbeam application, and radiation biological mechanism. (authors)

  3. Enhancing Biology Instruction with the Human Genome Project

    Science.gov (United States)

    Buxeda, Rosa J.; Moore-Russo, Deborah A.

    2003-01-01

    The Human Genome Project (HGP) is a recent scientific milestone that has received notable attention. This article shows how a biology course is using the HGP to enhance students' experiences by providing awareness of cutting edge research, with information on new emerging career options, and with opportunities to consider ethical questions raised…

  4. The History Research Project

    Science.gov (United States)

    Estes, Matt; Brady, Ann

    2005-01-01

    Matt Estes, a social studies teacher, mentions the main instructional goals for his students like understanding the importance of proper citation and attribution presenting the Machiavelli project that deals with the skills he wants his students to develop and the course material that must be covered. In addition, Ann Brady, a library media…

  5. Experimental Plasma Research project summaries

    International Nuclear Information System (INIS)

    1980-09-01

    This report contains descriptions of the activities supported by the Experimental Plasma Research Branch of APP. The individual project summaries were prepared by the principal investigators and include objectives and milestones for each project. The projects are arranged in six research categories: Plasma Properties; Plasma Heating; Plasma Diagnostics; Atomic, Molecular and Nuclear Physics; Advanced Superconducting Materials; and the Fusion Plasma Research Facility (FPRF). Each category is introduced with a statement of objectives and recent progress and followed by descriptions of individual projects. An overall budget summary is provided at the beginning of the report

  6. Experimental plasma research project summaries

    International Nuclear Information System (INIS)

    1978-08-01

    This report contans descriptions of the activities supported by the Experimental Plasma Research Branch of APP. The individual project summaries were prepared by the principal investigators and include objectives and milestones for each project. The projects are arranged in six research categories: Plasma Properties; Plasma Heating; Plasma Measurements and Instrumentation; Atomic, Molecular and Nuclear Physics; Advanced Superconducting Materials; and the Fusion Plasma Research Facility (FPRF). Each category is introduced with a statement of objectives and recent progress and followed by descriptions of individual projects. An overall budget summary is provided at the beginning of the report

  7. Experimental Plasma Research project summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-09-01

    This report contains descriptions of the activities supported by the Experimental Plasma Research Branch of APP. The individual project summaries were prepared by the principal investigators and include objectives and milestones for each project. The projects are arranged in six research categories: Plasma Properties; Plasma Heating; Plasma Diagnostics; Atomic, Molecular and Nuclear Physics; Advanced Superconducting Materials; and the Fusion Plasma Research Facility (FPRF). Each category is introduced with a statement of objectives and recent progress and followed by descriptions of individual projects. An overall budget summary is provided at the beginning of the report.

  8. Gordon Research Conference on Mammary Gland Biology

    International Nuclear Information System (INIS)

    1989-01-01

    The 1989 conference was the tenth in the series of biennial Gordon Research Conferences on Mammary Gland Biology. Traditionally this conference brings together scientists from diverse backgrounds and experience but with a common interest in the biology of the mammary gland. Investigators from agricultural and medical schools, biochemists, cell and molecular biologists, endocrinologists, immunologists, and representatives from the emerging biotechnology industries met to discuss current concepts and results on the function and regulation of the normal and neoplastic mammary gland in a variety of species. Of the participants, approximately three-fourths were engaged in studying the normal mammary gland function, whereas the other quarter were engaged in studying the neoplastic gland. The interactions between scientists, clinicians, veterinarians examining both normal and neoplastic cell function serves to foster the multi-disciplinary goals of the conference and has stimulated many cooperative projects among participants in previous years

  9. Research projects in radiobiology and radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1960-04-15

    Of the research projects sponsored by the International Atomic Energy Agency quite a large number are concerned with the biological effects of ionizing radiation. That itself, of course, is a very wide field covering such subjects as the nature and mechanism of radiation damage, genetic mutations, the varying radiosensitivity of different organisms, ways of modifying the natural sensitivity or resistance, and biological and chemical means of protection. In all these branches of enquiry, the Agency has awarded research contracts to scientific institutes or laboratories in different countries

  10. Research projects in radiobiology and radiation protection

    International Nuclear Information System (INIS)

    1960-01-01

    Of the research projects sponsored by the International Atomic Energy Agency quite a large number are concerned with the biological effects of ionizing radiation. That itself, of course, is a very wide field covering such subjects as the nature and mechanism of radiation damage, genetic mutations, the varying radiosensitivity of different organisms, ways of modifying the natural sensitivity or resistance, and biological and chemical means of protection. In all these branches of enquiry, the Agency has awarded research contracts to scientific institutes or laboratories in different countries

  11. Research Planning and Evaluation Project

    International Nuclear Information System (INIS)

    Song, Seunghyun; Kim, Doyang; Ryu, Byunghoon; Lim, Chaeyoung; Song, Leeyoung; Lee, Youngchul; Han, Changsun; Kim, Hackchoon

    2011-12-01

    - To activate R and D through a systematic and impartial evaluation by using information on efficient distribution of research resource, setting project priorities, and measuring achievement against goals produced after research on planning and evaluation system for the government-funded project for KAERI was conducted. - Nuclear R and D project is the representative national R and D project which has been implemented in Korea. For the sustainable development of nuclear energy which supplies about 40% of total electricity generation and the enhancement of it innovative ability in the future, a systematic and efficient strategy in the planning stage is required

  12. Biological Research for Radiation Protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Kug Chan; Jung, Il Lae; Choi, Yong Ho; Kim, Jin Sik; Moon, Myung Sook; Byun, Hee Sun; Phyo, Ki Heon; Kim, Sung Keun

    2005-04-01

    The work scope of 'Biological Research for the Radiation Protection' had contained the research about ornithine decarboxylase and its controlling proteins, thioredoxin, peroxiredoxin, S-adenosymethionine decarboxylase, and glutamate decarboxylase 67KD effect on the cell death triggered ionizing radiation and H 2 O 2 (toxic agents). In this study, to elucidate the role of these proteins in the ionizing radiation (or H 2 O 2 )-induced apoptotic cell death, we utilized sensesed (or antisensed) cells, which overexpress (or down-regulate) RNAs associated with these proteins biosynthesis, and investigated the effects of these genes on the cytotoxicity caused by ionizing radiation and H 2 O 2 (or paraquat). We also investigated whether genisteine(or thiamine) may enhance the cytotoxic efficacy of tumor cells caused by ionizing radiation (may enhance the preventing effect radiation or paraquat-induced damage) because such compounds are able to potentiate the cell-killing or cell protecting effects. Based on the above result, we suggest that the express regulation of theses genes have potentially importance for sensitizing the efficiency of radiation therapy of cancer or for protecting the radiation-induced damage of normal cells

  13. Biological research for radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Kim, In Gyu; Kim, Kug Chan; Shim, Hae Won; Oh, Tae Jeong; Park, Seon Young; Lee, Kang Suk

    2000-04-01

    The work scope of Biological research for the radiation protection had contained the search of biological microanalytic methods for assessing the health effect by {gamma}-radiation and toxic agents, the standardization of human T-lymphocyte cell culture and polymerase chain reaction, T-cell clonal assay, and the quantification of mutation frequency in the hypoxanthine (guanine) phosphoribosyl transferase (HPRT) gene locus by single exposure or combined exposure. Especially, the polymerase chain reaction methods using reverse transcriptase has been developed to analyze the mutant gene induced by {gamma}-radiation and chemical (pentachlorophenol) agent exposure, and to investigate the point mutations in the HPRT gene locus of T-lymphocytes. The HPRT T-cell clonal assay revealed that it could not differentiate {gamma}-irradiation from pentachlorophenol, because the frequency of somatic mutations induced by both damaging agents increased in a dose-dependent manner. The analysis of DNA sequence alterations of HPRT mutant clones clearly showed that both damaging agents induced different mutational spectra in the HPRT locus of T-cells. The large deletions, which account for 75 percent of the analyzed mutants, are characteristic mutations induced by {gamma}-irradiation. By contrast, point mutations such as base substitutions and insertion, come up to 97 percent in the case of pentachlorophenol-treated cells. The point mutation frequencies at 190 base pair and 444 base pair positions are 3-6 folds as high as in those at other mutation positions. It may be that these mutation sites are hot spots induced by pentachlorophenol. These results suggest that the HPRT mutation spectrum can be used as a potential bio marker for assessing a specific environmental risk. (author)

  14. Biological research for radiation protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Kug Chan; Shim, Hae Won; Oh, Tae Jeong; Park, Seon Young; Lee, Kang Suk

    2000-04-01

    The work scope of Biological research for the radiation protection had contained the search of biological microanalytic methods for assessing the health effect by γ-radiation and toxic agents, the standardization of human T-lymphocyte cell culture and polymerase chain reaction, T-cell clonal assay, and the quantification of mutation frequency in the hypoxanthine (guanine) phosphoribosyl transferase (HPRT) gene locus by single exposure or combined exposure. Especially, the polymerase chain reaction methods using reverse transcriptase has been developed to analyze the mutant gene induced by γ-radiation and chemical (pentachlorophenol) agent exposure, and to investigate the point mutations in the HPRT gene locus of T-lymphocytes. The HPRT T-cell clonal assay revealed that it could not differentiate γ-irradiation from pentachlorophenol, because the frequency of somatic mutations induced by both damaging agents increased in a dose-dependent manner. The analysis of DNA sequence alterations of HPRT mutant clones clearly showed that both damaging agents induced different mutational spectra in the HPRT locus of T-cells. The large deletions, which account for 75 percent of the analyzed mutants, are characteristic mutations induced by γ-irradiation. By contrast, point mutations such as base substitutions and insertion, come up to 97 percent in the case of pentachlorophenol-treated cells. The point mutation frequencies at 190 base pair and 444 base pair positions are 3-6 folds as high as in those at other mutation positions. It may be that these mutation sites are hot spots induced by pentachlorophenol. These results suggest that the HPRT mutation spectrum can be used as a potential bio marker for assessing a specific environmental risk. (author)

  15. Collaborative Systems Biology Projects for the Military Medical Community.

    Science.gov (United States)

    Zalatoris, Jeffrey J; Scheerer, Julia B; Lebeda, Frank J

    2017-09-01

    This pilot study was conducted to examine, for the first time, the ongoing systems biology research and development projects within the laboratories and centers of the U.S. Army Medical Research and Materiel Command (USAMRMC). The analysis has provided an understanding of the breadth of systems biology activities, resources, and collaborations across all USAMRMC subordinate laboratories. The Systems Biology Collaboration Center at USAMRMC issued a survey regarding systems biology research projects to the eight U.S.-based USAMRMC laboratories and centers in August 2016. This survey included a data call worksheet to gather self-identified project and programmatic information. The general topics focused on the investigators and their projects, on the project's research areas, on omics and other large data types being collected and stored, on the analytical or computational tools being used, and on identifying intramural (i.e., USAMRMC) and extramural collaborations. Among seven of the eight laboratories, 62 unique systems biology studies were funded and active during the final quarter of fiscal year 2016. Of 29 preselected medical Research Task Areas, 20 were associated with these studies, some of which were applicable to two or more Research Task Areas. Overall, studies were categorized among six general types of objectives: biological mechanisms of disease, risk of/susceptibility to injury or disease, innate mechanisms of healing, diagnostic and prognostic biomarkers, and host/patient responses to vaccines, and therapeutic strategies including host responses to therapies. We identified eight types of omics studies and four types of study subjects. Studies were categorized on a scale of increasing complexity from single study subject/single omics technology studies (23/62) to studies integrating results across two study subject types and two or more omics technologies (13/62). Investigators at seven USAMRMC laboratories had collaborations with systems biology experts

  16. Structural Biology and Molecular Applications Research

    Science.gov (United States)

    Part of NCI's Division of Cancer Biology's research portfolio, research and development in this area focuses on enabling technologies, models, and methodologies to support basic and applied cancer research.

  17. Math Fact Strategies Research Project

    Science.gov (United States)

    Boso, Annie

    2011-01-01

    An action research project was conducted in order to determine effective math fact strategies for first graders. The traditional way of teaching math facts included using timed tests and flashcards, with most students counting on their fingers or a number line. Six new research-based strategies were taught and analyzed to decide which methods…

  18. Experimental plasma research project summaries

    International Nuclear Information System (INIS)

    1982-10-01

    The experimental plasma Research Branch has responsibility for developing a broad range of experimental data and new experimental techniques that are required for operating and interpreting present large-scale confinement experiments, and for designing future deuterium-tritium burining facilities. The Branch pursued these objectives by supporting research in DOE laboratories, other Federal laboratories, other Federal laboratories, universities, and private industry. Initiation and renewal of research projects are primarily through submission of unsolicited proposals by these institutions to DOE. Summaries of these projects are given

  19. Plant Biology and Biogeochemistry Department annual project report 1999

    DEFF Research Database (Denmark)

    Jensen, A.; Gissel Nielsen, G.; Giese, H.

    2000-01-01

    The Department of Plant Biology and Biogeochemistry is engaged in basic and applied research to improve the scientific knowledge of developing new methods and technology for the future, environmentally benign industrial and agricultural production, thusexerting less stress and strain...... of Biomass, 3. DLF-Risø Biotechnology, 4. Plant Genetics and Epidemiology, 5. Biogeochemistry and 6. Plant Ecosystems and Nutrient Cycling. This electronicversion of the annual report from the Plant Biology and Biogeochemistry Department aims to provide information about the progress in our research. Each...... on the environment. This knowledge will lead to a greater prosperity and welfare for agriculture, industry and consumers in Denmark. The research approach in the Department is mainly experimental and the projects areorganized in six research programmes: 1. Plant-Microbe Symbioses, 2. Plant Products and Recycling...

  20. 20% Research & Design Science Project

    Science.gov (United States)

    Spear, Beth A.

    2015-04-01

    A project allowing employees to use 15 % of their time on independent projects was established at 3M in the 1950's. The result of this project included products like post it notes and masking tape. Google allows its employees to use 20% of their time on independently pursued projects. The company values creativity and innovation. Employees are allowed to explore projects of interest to them one day out of the week, 20 % of their work week. Products like AdSense, Gmail, Google Transit, Google News, and Google Talk are the result of this 20 % program. My school is implementing the Next Generation Science Standards (NGSS) as part of our regularly scheduled curriculum review. These new standards focus on the process of learning by doing and designing. The NGSS are very hands on and active. The new standards emphasize learning how to define, understand and solve problems in science and technology. In today's society everyone needs to be familiar with science and technology. This project allows students to develop and practice skills to help them be more comfortable and confident with science and technology while exploring something of interest to them. This project includes three major parts: research, design, and presentation. Students will spend approximately 2-4 weeks defining a project proposal and educating themselves by researching a science and technology topic that is of interest to them. In the next phase, 2-4 weeks, students design a product or plan to collect data for something related to their topic. The time spent on research and design will be dependant on the topic students select. Projects should be ambitious enough to encompass about six weeks. Lastly a presentation or demonstration incorporating the research and design of the project is created, peer reviewed and presented to the class. There are some problems anticipated or already experienced with this project. It is difficult for all students to choose a unique topic when you have large class sizes

  1. Haldane's Contributions to Biological Research in India

    Indian Academy of Sciences (India)

    and Industrial Research, New Delhi, he moved to Bhubaneswar to start his own ... Brown, Foreign Secretary, US National Academy of Sciences, in. 1964, upon .... lectures contained new ideas for biological research that could be conducted in ...

  2. Current research in Canada on biological effects of ionizing radiation

    International Nuclear Information System (INIS)

    Marko, A.M.

    1980-05-01

    A survey of current research in Canada on the biological effects of ionizing radiation has been compiled. The list of projects has been classified according to structure (organizational state of the test system) as well as according to the type of effects. Using several assumptions, ballpark estimates of expenditures on these activities have been made. Agencies funding these research activities have been tabulated and the break-down of research in government laboratories and in academic institutions has been designated. Wherever possible, comparisons have been made outlining differences or similarities that exist between the United States and Canada concerning biological radiation research. It has been concluded that relevant research in this area in Canada is inadequate. Wherever possible, strengths and weaknesses in radiation biology programs have been indicated. The most promising course for Canada to follow is to support adequately fundamental studies of the biological effects of radiation. (auth)

  3. Learning Cell Biology as a Team: A Project-Based Approach to Upper-Division Cell Biology

    Science.gov (United States)

    Wright, Robin; Boggs, James

    2002-01-01

    To help students develop successful strategies for learning how to learn and communicate complex information in cell biology, we developed a quarter-long cell biology class based on team projects. Each team researches a particular human disease and presents information about the cellular structure or process affected by the disease, the cellular…

  4. Data integration in biological research: an overview.

    Science.gov (United States)

    Lapatas, Vasileios; Stefanidakis, Michalis; Jimenez, Rafael C; Via, Allegra; Schneider, Maria Victoria

    2015-12-01

    Data sharing, integration and annotation are essential to ensure the reproducibility of the analysis and interpretation of the experimental findings. Often these activities are perceived as a role that bioinformaticians and computer scientists have to take with no or little input from the experimental biologist. On the contrary, biological researchers, being the producers and often the end users of such data, have a big role in enabling biological data integration. The quality and usefulness of data integration depend on the existence and adoption of standards, shared formats, and mechanisms that are suitable for biological researchers to submit and annotate the data, so it can be easily searchable, conveniently linked and consequently used for further biological analysis and discovery. Here, we provide background on what is data integration from a computational science point of view, how it has been applied to biological research, which key aspects contributed to its success and future directions.

  5. Teaching/Research Project "Wheelmap"

    Science.gov (United States)

    Gollenstede, Andreas

    2018-05-01

    In recent years new didactic concepts and approaches have been developed and evaluated at the universities. The concept for cartography lectures presented in this article is based on the close link of research and teaching/learning. The students are involved in all essential steps of a scientific project taking place during a series of lectures - beginning with the development of the scientific issues, followed by the choice and execution of the research methods and finally the presentation of the achieved outcomes. The specific project introduced here is based on self-experiments in which students took the perspective of wheelchair users entrusted with the task to map places, which are accessible for people with impairments. Among others, the goal set for the students was to develop an appropriate concept for the mobile acquisition of data and to visualise the final results by different methods of cartography.

  6. Coordinated research projects (CRP). Coordinated research project (CRP)

    International Nuclear Information System (INIS)

    Takagi, Hidekazu; Koike, Fumihiro; Nakamura, Nobuyuki

    2013-01-01

    In the present paper, the contribution of Japanese scientists in coordinated research projects on thermonuclear fusion. Representative subjects taken in seven projects are the precise computation of theoretical data on electron-molecule collisions in the peripheral plasma, the computation of spectroscopic data of multi-charged tungsten ions, the spectroscopic measurement of multi-charged tungsten ions using an ion trap device, the development of collisional-radiative model for plasmas including hydrogen and helium, the computational and theoretical studies on the behavior of tungsten and beryllium in the plasma-wall interaction, the study on the property of dusts generated in fusion devices. These subjects are those of most important issues in ITER. (author)

  7. A Community-Building Framework for Collaborative Research Coordination across the Education and Biology Research Disciplines

    Science.gov (United States)

    Pelaez, Nancy; Anderson, Trevor R.; Gardner, Stephanie M.; Yin, Yue; Abraham, Joel K.; Barlett, Edward L.; Gormally, Cara; Hurney, Carol A.; Long, Tammy M.; Newman, Dina L.; Sirum, Karen; Stevens, Michael T.

    2018-01-01

    Since 2009, the U.S. National Science Foundation Directorate for Biological Sciences has funded Research Coordination Networks (RCN) aimed at collaborative efforts to improve participation, learning, and assessment in undergraduate biology education (UBE). RCN-UBE projects focus on coordination and communication among scientists and educators who…

  8. Biotechnology by Design: An Introductory Level, Project-Based, Synthetic Biology Laboratory Program for Undergraduate Students†

    OpenAIRE

    Beach, Dale L.; Alvarez, Consuelo J.

    2015-01-01

    Synthetic biology offers an ideal opportunity to promote undergraduate laboratory courses with research-style projects, immersing students in an inquiry-based program that enhances the experience of the scientific process. We designed a semester-long, project-based laboratory curriculum using synthetic biology principles to develop a novel sensory device. Students develop subject matter knowledge of molecular genetics and practical skills relevant to molecular biology, recombinant DNA techniq...

  9. Experimental plasma research project summaries

    International Nuclear Information System (INIS)

    1992-06-01

    This is the latest in a series of Project Summary books going back to 1976 and is the first after a hiatus of several years. They are published to provide a short description of each project supported by the Experimental Plasma Research Branch of the Division of Applied Plasma Physics in the Office of Fusion Energy. The Experimental Plasma Research Branch seeks to provide a broad range of experimental data, physics understanding, and new experimental techniques that contribute to operation, interpretation, and improvement of high temperature plasma as a source of fusion energy. In pursuit of these objectives, the branch supports research at universities, DOE laboratories, other federal laboratories and industry. About 70 percent of the funds expended are spent at universities and a significant function of this program is the training of students in fusion physics. The branch supports small- and medium-scale experimental studies directly related to specific critical plasma issues of the magnetic fusion program. Plasma physics experiments are conducted on transport of particles and energy within plasma and innovative approaches for operating, controlling, and heating plasma are evaluated for application to the larger confinement devices of the magnetic fusion program. New diagnostic approaches to measuring the properties of high temperature plasmas are developed to the point where they can be applied with confidence on the large-scale confinement experiments. Atomic data necessary for impurity control, interpretation of diagnostic data, development of heating devices, and analysis of cooling by impurity ion radiation are obtained. The project summaries are grouped into these three categories of plasma physics, diagnostic development and atomic physics

  10. Research project at Nagoya University

    International Nuclear Information System (INIS)

    Furukawa, M.; Nakai, N.; Nakano, E.

    1981-01-01

    We will have a dedicated facility from General Ionex Corporation at the Radioisotope Center of Nagoya Univeriy in 1981 FY. The building to install the machine was already completed in March 1981. We have held meetings of potential users of the facility and various research proposals have been presented by the participants from many departments of the university. The present research project at Nagoya is mainly devoted to the development of radiocarbon dating by the accelerator mass spectrometry, in which most of the users are interested. There are many archeological and geological samples in Japan which have too little carbon compounds for analysis by conventional radioactivity measurements. Concentrations of 14 C in these samples can be determined by the new technique. Some of the proposals connected with radiocarbon measurements are discussed

  11. Management of research and development project

    International Nuclear Information System (INIS)

    Go, Seok Hwa; Hong Jeong Yu; Hyun, Byeong Hwan

    2010-12-01

    This book introduces summary on management of research and development project, prepare of research and development with investigation and analysis of paper, patent and trend of technology, structure of project, management model, management of project, management of project range, management of project time, management of project cost, management of project goods, management of project manpower, management of communication, management of project risk, management of project supply, management of outcome of R and D, management of apply and enroll of patent and management of technology transfer.

  12. South African antarctic biological research programme

    CSIR Research Space (South Africa)

    SASCAR

    1981-07-01

    Full Text Available This document provides a description of the past, current and planned South African biological research activities in the sub-Antarctic and Antarctic regions. Future activities will fall under one of the five components of the research programme...

  13. Activities in biological radiation research at the AGF

    International Nuclear Information System (INIS)

    1984-01-01

    The AGF is working on a wide spectrum of biological radiation research, with the different scientific disciplines contributing different methodologies to long-term research projects. The following fields are studied: 1. Molecular and cellular modes of action of radiation. 2. Detection and characterisation of biological radiation damage, especially in humans. 3. Medical applications of radiation effects. 4. Concepts and methods of radiation protection. The studies will lead to suggestions for radiation protection and improved radiotherapy. They may also contribute to the development of environmental protection strategies. (orig./MG) [de

  14. Agreements and Discrepancies between FDA Reports and Journal Papers on Biologic Agents Approved for Rheumatoid Arthritis: A Meta-Research Project.

    Directory of Open Access Journals (Sweden)

    Gil Amarilyo

    Full Text Available Sponsors that seek to commercialize new drugs apply to the Food and Drug Administration (FDA which independently analyzes the raw data and reports the results on its website.This study sought to determine if there are differences between the FDA assessments and journal reports on biologic agents developed for the treatment of rheumatoid arthritis.Available data on FDA-approved drugs were extracted from the website, and a systematic literature search was conducted to identify matching studies in peer-reviewed medical journals. Outcome measures were the American College of Rheumatology response criteria ACR20 (efficacy and withdrawal due to adverse events (safety. As effect size odds ratios were estimated for each active trial arm vs. control arm (i.e. for both sources: FDA and journal report, followed by calculation of the ratios of the FDA and journal report odds ratios. A ratio of odds ratios not equal to 1 was categorized as a discrepancy.FDA reports were available for 8 of 9 FDA-approved biologic agents for rheumatoid arthritis; all identified trials (34 except one were published in peer-reviewed journals. Overall, discrepancies were noted for 20 of the 33 evaluated trials. Differences in the apparent benefit reporting were found in 39% (24/61 pairwise comparisons and in 11 cases these were statistically significant; the FDA report showed greater benefit than the journal publication in 15 comparisons and lesser benefit in 9. Differences in the reported harms were found in 51% (28/55 pairwise comparisons and were statistically significant in 5. The "signal" in FDA reports showed a less harmful effect than the journal publication in 17 comparisons whereas a more harmful effect in 11. The differences were attributed to differences in analytic approach, patient inclusion, rounding effect, and counting discrepancies. However, no differences were categorized as critical.There was no empirical evidence to suggest biased estimates between the two

  15. Australia's replacement research reactor project

    International Nuclear Information System (INIS)

    Harris, K.J.

    1999-01-01

    HIFAR, a 10 MW tank type DIDO Class reactor has operated at the Lucas Heights Science and Technology Centre for 43 years. HIFAR and the 10 kW Argonaut reactor 'Moata' which is in the Care and Maintenance phase of decommissioning are Australia's only nuclear reactors. The initial purpose for HIFAR was for materials testing to support a nuclear power program. Changing community attitude through the 1970's and a Government decision not to proceed with a planned nuclear power reactor resulted in a reduction of materials testing activities and a greater emphasis being placed on neutron beam research and the production of radioisotopes, particularly for medical purposes. HIFAR is not fully capable of satisfying the expected increase in demand for medical radiopharmaceuticals beyond the next 5 years and the radial configuration of the beam tubes severely restricts the scope and efficiency of neutron beam research. In 1997 the Australian Government decided that a replacement research reactor should be built by the Australian Nuclear Science and Technology Organisation at Lucas Heights subject to favourable results of an Environmental Impact Study. The Ei identified no reasons on the grounds of safety, health, hazard or risk to prevent construction on the preferred site and it was decided in May 1999 that there were no environmental reasons why construction of the facility should not proceed. In recent years ANSTO has been reviewing the operation of HIFAR and observing international developments in reactor technology. Limitations in the flexibility and efficiency achievable in operation of a tank type reactor and the higher intrinsic safety sought in fundamental design resulted in an early decision that the replacement reactor must be a pool type having cleaner and higher intensity tangential neutron beams of wider energy range than those available from HIFAR. ANSTO has chosen to use it's own resources supported by specialised external knowledge and experience to identify

  16. FY 2001 report on the integrated evaluation of the research cooperation project. Research cooperation program on the development of environmental measurement use laser radar/research cooperation project on the mining waste water treatment technology using biology; 2001 nendo kenkyu kyoryoku jigyo sogo hyoka hokokusho. Kankyo kesokuyo reza reda no kaihatsu ni kansuru kenkyu kyoryoku - Baio riyo ni yoru kohaisui shori gijutsu ni kansuru kenkyu kyoryoku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-03-01

    By research groups having been sent, the integrated evaluation was made of the projects on the research cooperation with Indonesia in the development of environmental measurement use laser radar and the research cooperation with China in the mining waste water treatment technology using biology. As to the research cooperation with Indonesia, the purpose/target proposed were almost achieved, and all were favorably carried out. Especially, after finishing the project, the design/manufacture of an on-vehicle type Mie-scattering laser radar were made using the acquired laser technology. And, it was reported that an observation study of the state of air pollution in Bandung city was made using the laser radar. It can be said that generally the research cooperation with China was smoothly proceeded with. However, the Wushan mine is small in scale of management, and therefore, there might have been some points to be reviewed in selection of the mine for research. The pilot plant installed at the Wushan mine is not now operated. If the mine has strong management force, the effective use of the pilot plant after finishing the project might have been studied. (NEDO)

  17. Human genome project: revolutionizing biology through leveraging technology

    Science.gov (United States)

    Dahl, Carol A.; Strausberg, Robert L.

    1996-04-01

    The Human Genome Project (HGP) is an international project to develop genetic, physical, and sequence-based maps of the human genome. Since the inception of the HGP it has been clear that substantially improved technology would be required to meet the scientific goals, particularly in order to acquire the complete sequence of the human genome, and that these technologies coupled with the information forthcoming from the project would have a dramatic effect on the way biomedical research is performed in the future. In this paper, we discuss the state-of-the-art for genomic DNA sequencing, technological challenges that remain, and the potential technological paths that could yield substantially improved genomic sequencing technology. The impact of the technology developed from the HGP is broad-reaching and a discussion of other research and medical applications that are leveraging HGP-derived DNA analysis technologies is included. The multidisciplinary approach to the development of new technologies that has been successful for the HGP provides a paradigm for facilitating new genomic approaches toward understanding the biological role of functional elements and systems within the cell, including those encoded within genomic DNA and their molecular products.

  18. Radioactive 63Ni in biological research

    International Nuclear Information System (INIS)

    Kasprzak, K.S.; Sunderman, F.W. Jr.

    1979-01-01

    Applications of 63 Ni in biological research are reviewed, with emphasis upon recent investigations of nickel metabolism and toxicology in experimental animals. The radiochemistry of 63 Ni is summarized, including consideration of the preparation of certain 63 Ni compounds (e.g. 63 Ni(CO) 4 and 63 Ni 3 S 2 ) that are of current interest in toxicology, teratology and cancer research. Practical guidance is given regarding the detection and determination of 63 Ni in biological materials by autoradiography and liquid scintillation spectrometry. (author)

  19. [The research project: financing and management].

    Science.gov (United States)

    Schena, F P

    2003-01-01

    Basic and clinical research is accomplished by projects. The design of a project is not only based on the scientific content but also on its financing and management. This article wants to illustrate the correct modalities for project financing and project management in a scientific project.

  20. 75 FR 6651 - Biological and Environmental Research Advisory Committee

    Science.gov (United States)

    2010-02-10

    ... DEPARTMENT OF ENERGY Biological and Environmental Research Advisory Committee AGENCY: Department... meeting of the Biological and Environmental Research Advisory Committee (BERAC). Federal Advisory.... Department of Energy, Office of Science, Office of Biological and Environmental Research, SC-23/Germantown...

  1. 77 FR 4028 - Biological and Environmental Research Advisory Committee

    Science.gov (United States)

    2012-01-26

    ... DEPARTMENT OF ENERGY Biological and Environmental Research Advisory Committee AGENCY: Department... meeting of the Biological and Environmental Research Advisory Committee (BERAC). The Federal Advisory.... Department of Energy, Office of Science, Office of Biological and Environmental Research, SC-23/Germantown...

  2. System biology and the project Encode

    Directory of Open Access Journals (Sweden)

    M. Yu. Obolenskaya

    2014-08-01

    Full Text Available The goal of this review is to give an incipient knowledge on the background of system biology, the premises to its assignment as a new branch of biology, its principles, methodology and its great achievements in identification of functional elements of human genome and regulation of their concordant­ and differential activity. The short characteristics of functional elements including the protein-coding sequences and those coding noncoding RNAs, the DNAse 1 hypersensitivity sites and methylated CpG islets, modified histones and specific 3D structure of chromatin, are represented. The topology of transcription factors network with its main motifs, hierar­chy, combination and association of transcription factors and their allelic specificity are highlighted­.

  3. CSBB: synthetic biology research at Newcastle University.

    Science.gov (United States)

    Goñi-Moreno, Angel; Wipat, Anil; Krasnogor, Natalio

    2017-06-15

    The Centre for Synthetic Biology and the Bioeconomy (CSBB) brings together a far-reaching multidisciplinary community across all Newcastle University's faculties - Medical Sciences, Science, Agriculture and Engineering, and Humanities, Arts and Social Sciences. The CSBB focuses on many different areas of Synthetic Biology, including bioprocessing, computational design and in vivo computation, as well as improving understanding of basic molecular machinery. Such breadth is supported by major national and international research funding, a range of industrial partners in the North East of England and beyond, as well as a large number of doctoral and post-doctoral researchers. The CSBB trains the next generation of scientists through a 1-year MSc in Synthetic Biology. © 2017 The Author(s).

  4. The Human Genome Project and Biology Education.

    Science.gov (United States)

    McInerney, Joseph D.

    1996-01-01

    Highlights the importance of the Human Genome Project in educating the public about genetics. Discusses four challenges that science educators must address: teaching for conceptual understanding, the nature of science, the personal and social impact of science and technology, and the principles of technology. Contains 45 references. (JRH)

  5. Adapting Project Management Practices to Research-Based Projects

    Science.gov (United States)

    Bahr, P.; Baker, T.; Corbin, B.; Keith, L.; Loerch, L.; Mullenax, C.; Myers, R.; Rhodes, B.; Skytland, N.

    2007-01-01

    From dealing with the inherent uncertainties in outcomes of scientific research to the lack of applicability of current NASA Procedural Requirements guidance documentation, research-based projects present challenges that require unique application of classical project management techniques. If additionally challenged by the creation of a new program transitioning from basic to applied research in a technical environment often unfamiliar with the cost and schedule constraints addressed by project management practices, such projects can find themselves struggling throughout their life cycles. Finally, supplying deliverables to a prime vehicle customer, also in the formative stage, adds further complexity to the development and management of research-based projects. The Biomedical Research and Countermeasures Projects Branch at NASA Johnson Space Center encompasses several diverse applied research-based or research-enabling projects within the newly-formed Human Research Program. This presentation will provide a brief overview of the organizational structure and environment in which these projects operate and how the projects coordinate to address and manage technical requirements. We will identify several of the challenges (cost, technical, schedule, and personnel) encountered by projects across the Branch, present case reports of actions taken and techniques implemented to deal with these challenges, and then close the session with an open forum discussion of remaining challenges and potential mitigations.

  6. 78 FR 6087 - Biological and Environmental Research Advisory Committee

    Science.gov (United States)

    2013-01-29

    ... DEPARTMENT OF ENERGY Biological and Environmental Research Advisory Committee AGENCY: Office of... the Biological and Environmental Research Advisory Committee (BERAC). The Federal Advisory Committee... Federal Officer, BERAC, U.S. Department of Energy, Office of Science, Office of Biological and...

  7. Current dichotomy between traditional molecular biological and omic research in cancer biology and pharmacology.

    Science.gov (United States)

    Reinhold, William C

    2015-12-10

    There is currently a split within the cancer research community between traditional molecular biological hypothesis-driven and the more recent "omic" forms or research. While the molecular biological approach employs the tried and true single alteration-single response formulations of experimentation, the omic employs broad-based assay or sample collection approaches that generate large volumes of data. How to integrate the benefits of these two approaches in an efficient and productive fashion remains an outstanding issue. Ideally, one would merge the understandability, exactness, simplicity, and testability of the molecular biological approach, with the larger amounts of data, simultaneous consideration of multiple alterations, consideration of genes both of known interest along with the novel, cross-sample comparisons among cell lines and patient samples, and consideration of directed questions while simultaneously gaining exposure to the novel provided by the omic approach. While at the current time integration of the two disciplines remains problematic, attempts to do so are ongoing, and will be necessary for the understanding of the large cell line screens including the Developmental Therapeutics Program's NCI-60, the Broad Institute's Cancer Cell Line Encyclopedia, and the Wellcome Trust Sanger Institute's Cancer Genome Project, as well as the the Cancer Genome Atlas clinical samples project. Going forward there is significant benefit to be had from the integration of the molecular biological and the omic forms or research, with the desired goal being improved translational understanding and application.

  8. Advanced Energy Projects FY 1990 research summaries

    International Nuclear Information System (INIS)

    1990-09-01

    This report serves as a guide to prepare proposals and provides summaries of the research projects active in FY 1990, sponsored by the Office of Basic Energy Sciences Division of Advanced Energy Projects, Department of Energy. (JF)

  9. NCDP Research Projects and Research Supported Projects (June ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Amal Ben Ameur

    prevent non-communicable diseases in India. 139,600. India. Asia ... Building the field of research on non- ... Assessing the attitudes and practices of public ... Tobacco control Research on health costs of smoking in Cambodia. 14,800.

  10. Innovative finance : strategic research project.

    Science.gov (United States)

    2013-08-01

    Its time to rethink how we fund transportation infrastructure because most transportation : experts agree: theres a transportation funding and financing crisis looming. : Projected revenues from current sources of transportation funding will am...

  11. Onchocerciasis control: biological research is still needed

    Directory of Open Access Journals (Sweden)

    Boussinesq M.

    2008-09-01

    Full Text Available Achievements obtained by the onchocerciasis control programmes should not lead to a relaxation in the biological research on Onchocerca volvulus. Issues such as the Loa loa-related postivermectin serious adverse events, the uncertainties as to whether onchocerciasis can be eliminated by ivermectin treatments, and the possible emergence of ivermectin-resistant O. volvulus populations should be addressed proactively. Doxycycline, moxidectin and emodepside appear to be promising as alternative drugs against onchocerciasis but support to researches in immunology and genomics should also be increased to develop new control tools, including both vaccines and macrofilaricidal drugs.

  12. An O-"fish"-ial Research Project

    Science.gov (United States)

    Newman, James; Krustchinsky, Rick; Vanek, Karen; Nguyen, Kim-Thoa

    2009-01-01

    In this "O-"fish"-ial" research project, third-grade students use multiple resources to research several fish species, write a research paper and develop a PowerPoint presentation to communicate their findings. In addition, students actually examine these species up close with samples from the local market, and then conclude the project with a…

  13. Biological effectiveness of neutrons: Research needs

    Energy Technology Data Exchange (ETDEWEB)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

  14. Biological effectiveness of neutrons: Research needs

    International Nuclear Information System (INIS)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy

  15. Making Research Fly in Schools: "Drosophila" as a Powerful Modern Tool for Teaching Biology

    Science.gov (United States)

    Harbottle, Jennifer; Strangward, Patrick; Alnuamaani, Catherine; Lawes, Surita; Patel, Sanjai; Prokop, Andreas

    2016-01-01

    The "droso4schools" project aims to introduce the fruit fly "Drosophila" as a powerful modern teaching tool to convey curriculum-relevant specifications in biology lessons. Flies are easy and cheap to breed and have been at the forefront of biology research for a century, providing unique conceptual understanding of biology and…

  16. National Biological Service Research Supports Watershed Planning

    Science.gov (United States)

    Snyder, Craig D.

    1996-01-01

    The National Biological Service's Leetown Science Center is investigating how human impacts on watershed, riparian, and in-stream habitats affect fish communities. The research will provide the basis for a Ridge and Valley model that will allow resource managers to accurately predict and effectively mitigate human impacts on water quality. The study takes place in the Opequon Creek drainage basin of West Virginia. A fourth-order tributary of the Potomac, the basin falls within the Ridge and Valley. The study will identify biological components sensitive to land use patterns and the condition of the riparian zone; the effect of stream size, location, and other characteristics on fish communities; the extent to which remote sensing can reliable measure the riparian zone; and the relationship between the rate of landscape change and the structure of fish communities.

  17. Projective techniques in consumer research

    African Journals Online (AJOL)

    privaat

    Various projective techniques for personality assess- ment and psychoanalytic treatment in clinical psychol- .... Some social conventions or barriers may constrain the expression of feelings and reporting of behav- .... ject-stipulated characteristic. Brand mapping may be used in new product development and as a way to.

  18. Research Project Evaluation-Learnings from the PATHWAYS Project Experience.

    Science.gov (United States)

    Galas, Aleksander; Pilat, Aleksandra; Leonardi, Matilde; Tobiasz-Adamczyk, Beata

    2018-05-25

    Every research project faces challenges regarding how to achieve its goals in a timely and effective manner. The purpose of this paper is to present a project evaluation methodology gathered during the implementation of the Participation to Healthy Workplaces and Inclusive Strategies in the Work Sector (the EU PATHWAYS Project). The PATHWAYS project involved multiple countries and multi-cultural aspects of re/integrating chronically ill patients into labor markets in different countries. This paper describes key project's evaluation issues including: (1) purposes, (2) advisability, (3) tools, (4) implementation, and (5) possible benefits and presents the advantages of a continuous monitoring. Project evaluation tool to assess structure and resources, process, management and communication, achievements, and outcomes. The project used a mixed evaluation approach and included Strengths (S), Weaknesses (W), Opportunities (O), and Threats (SWOT) analysis. A methodology for longitudinal EU projects' evaluation is described. The evaluation process allowed to highlight strengths and weaknesses and highlighted good coordination and communication between project partners as well as some key issues such as: the need for a shared glossary covering areas investigated by the project, problematic issues related to the involvement of stakeholders from outside the project, and issues with timing. Numerical SWOT analysis showed improvement in project performance over time. The proportion of participating project partners in the evaluation varied from 100% to 83.3%. There is a need for the implementation of a structured evaluation process in multidisciplinary projects involving different stakeholders in diverse socio-environmental and political conditions. Based on the PATHWAYS experience, a clear monitoring methodology is suggested as essential in every multidisciplinary research projects.

  19. Biological and chemical technologies research. FY 1995 annual summary report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-03-01

    The annual summary report presents the fiscal year (FY) 1995 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program. This BCTR program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1995 (ASR 95) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization, selected technical and programmatic highlights for 1995; detailed descriptions of individual projects; a listing of program output, including a bibliography of published work; patents; and awards arising from work supported by the BCTR.

  20. International Research and Development in Systems Biology

    Science.gov (United States)

    2005-10-01

    Genetics Berlin, Germany Hans Lehrach, Edda Klipp, Silke Sperling Yeast stress response and mitochondrial damage; Downs syndrome; cardiac...molgen.mpg.de, Dr. Edda Klipp, Axel Kowald, Christoph Wierling, Dr. Silke Sperling BACKGROUND The Max Planck Institute for Molecular Genetics was...the cardiovascular genetics group. RESEARCH PROJECTS Dr. Edda Klipp is the head of the kinetic modeling group. She described her group’s

  1. Overview of research in the ADVANTAGE project

    DEFF Research Database (Denmark)

    Angjelichinoski, Marko; Cosovic, Mirsad; Kalalas, Charalampos

    2016-01-01

    The European Marie Curie Project ADVANTAGE (Advanced Communications and Information processing in smart grid systems) was launched in 2014. It represents a major inter-disciplinary research project into the topic of Smart Grid technology. A key aspect of the project is to bring together and train...

  2. Advanced Energy Projects: FY 1993, Research summaries

    International Nuclear Information System (INIS)

    1993-09-01

    AEP has been supporting research on novel materials for energy technology, renewable and biodegradable materials, new uses for scientific discoveries, alternate pathways to energy efficiency, alternative energy sources, innovative approaches to waste treatment and reduction, etc. The summaries are grouped according to projects active in FY 1993, Phase I SBIR projects, and Phase II SBIR projects. Investigator and institutional indexes are included

  3. Advanced Energy Projects: FY 1993, Research summaries

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    AEP has been supporting research on novel materials for energy technology, renewable and biodegradable materials, new uses for scientific discoveries, alternate pathways to energy efficiency, alternative energy sources, innovative approaches to waste treatment and reduction, etc. The summaries are grouped according to projects active in FY 1993, Phase I SBIR projects, and Phase II SBIR projects. Investigator and institutional indexes are included.

  4. Basic Project Management Methodologies for Survey Researchers.

    Science.gov (United States)

    Beach, Robert H.

    To be effective, project management requires a heavy dependence on the document, list, and computational capability of a computerized environment. Now that microcomputers are readily available, only the rediscovery of classic project management methodology is required for improved resource allocation in small research projects. This paper provides…

  5. Geothermal Reservoir Technology Research Program: Abstracts of selected research projects

    Energy Technology Data Exchange (ETDEWEB)

    Reed, M.J. (ed.)

    1993-03-01

    Research projects are described in the following areas: geothermal exploration, mapping reservoir properties and reservoir monitoring, and well testing, simulation, and predicting reservoir performance. The objectives, technical approach, and project status of each project are presented. The background, research results, and future plans for each project are discussed. The names, addresses, and telephone and telefax numbers are given for the DOE program manager and the principal investigators. (MHR)

  6. The Human Genome Project: big science transforms biology and medicine

    OpenAIRE

    Hood, Leroy; Rowen, Lee

    2013-01-01

    The Human Genome Project has transformed biology through its integrated big science approach to deciphering a reference human genome sequence along with the complete sequences of key model organisms. The project exemplifies the power, necessity and success of large, integrated, cross-disciplinary efforts - so-called ‘big science’ - directed towards complex major objectives. In this article, we discuss the ways in which this ambitious endeavor led to the development of novel technologies and a...

  7. Applications of NMR in biological metabolic research

    International Nuclear Information System (INIS)

    Nie Jiarui; Li Xiuqin; He Chunjian

    1989-01-01

    The nuclear magnetic resonance has become a powerful means of studying biological metabolism in non-invasive and non-destructive way. Being used to study the metabolic processes of living system in normal physiological conditions as well as in molecular level, the method is better than other conventional approaches. Using important parameters such as NMR-chemical shifts, longitudinal relaxation time and transverse relaxation time, it is possible to probe the metabolic processes as well as conformation, concentration, transportation and distribution of reacting and resulting substances. The NMR spectroscopy of 1 H, 31 P and 13 C nuclei has already been widely used in metabolic researches

  8. Solar Market Research and Analysis Projects | Solar Research | NREL

    Science.gov (United States)

    Market Research and Analysis Projects Solar Market Research and Analysis Projects Solar market research and analysis efforts at NREL seek to further solar technologies' role in supporting a more . Midscale Commercial Market Solar Analysis NREL experts are providing analysis to expand the midscale solar

  9. Synergy between medicinal chemistry and biological research.

    Science.gov (United States)

    Moncada, Salvador; Coaker, Hannah

    2014-09-01

    Salvador Moncada studied medicine at the University of El Salvador (El Salvador) before coming to the UK in 1971 to work on a PhD with Professor John Vane at the Institute of Basic Medical Sciences, Royal College of Surgeons (UK). After a short period of research at the University of Honduras (Honduras), he joined the Wellcome Research Laboratories (UK) where he became Head of the Department of Prostaglandin Research and later, Director of Research. He returned to academic life in 1996 as founder and director of the Wolfson Institute for Biomedical Research at University College London (UK). Moncada played a role in the discovery of the mechanism of action of aspirin-like drugs and later led the teams which discover prostacyclin and identified nitric oxide as a biological mediator. In his role as a Director of Research of the Wellcome Laboratories, he oversaw the discovery and development of medicines for epilepsy, migraine, malaria and cancer. Currently, he is working on the regulation of cell proliferation as Director of the Institute of Cancer Sciences at the University of Manchester (UK). Moncada has won numerous awards from the international scientific community and in 2010, he received a knighthood from Her Majesty Queen Elizabeth II for his services to science.

  10. Modeling Research Project Risks with Fuzzy Maps

    Science.gov (United States)

    Bodea, Constanta Nicoleta; Dascalu, Mariana Iuliana

    2009-01-01

    The authors propose a risks evaluation model for research projects. The model is based on fuzzy inference. The knowledge base for fuzzy process is built with a causal and cognitive map of risks. The map was especially developed for research projects, taken into account their typical lifecycle. The model was applied to an e-testing research…

  11. Advanced energy projects FY 1992 research summaries

    International Nuclear Information System (INIS)

    1992-09-01

    The Division of Advanced Energy Projects (AEP) provides support to explore the feasibility of novel, energy-related concepts that evolve from advances in basic research. These concepts are typically at an early stage of scientific definition and, therefore, are beyond the scope of ongoing applied research or technology development programs. The Division provides a mechanism for converting basic research findings to applications that eventually could impact the Nation's energy economy. Technical topics include physical, chemical, materials, engineering, and biotechnologies. Projects can involve interdisciplinary approaches to solve energy-related problems. Projects are supported for a finite period of time, which is typically three years. Annual funding levels for projects are usually about $300,000 but can vary from approximately $50,000 to $500,000. It is expected that, following AEP support, each concept will be sufficiently developed and promising to attract further funding from other sources in order to realize its full potential. There were 39 research projects in the Division of Advanced Energy Projects during Fiscal Year 1992 (October 1, 1991 -- September 30, 1992). The abstracts of those projects are provided to introduce the overall program in Advanced Energy Projects. Further information on a specific project may be obtained by contacting the principal investigator, who is listed below the project title. Projects completed during FY 1992 are indicated

  12. Research Project Evaluation—Learnings from the PATHWAYS Project Experience

    Directory of Open Access Journals (Sweden)

    Aleksander Galas

    2018-05-01

    Full Text Available Background: Every research project faces challenges regarding how to achieve its goals in a timely and effective manner. The purpose of this paper is to present a project evaluation methodology gathered during the implementation of the Participation to Healthy Workplaces and Inclusive Strategies in the Work Sector (the EU PATHWAYS Project. The PATHWAYS project involved multiple countries and multi-cultural aspects of re/integrating chronically ill patients into labor markets in different countries. This paper describes key project’s evaluation issues including: (1 purposes, (2 advisability, (3 tools, (4 implementation, and (5 possible benefits and presents the advantages of a continuous monitoring. Methods: Project evaluation tool to assess structure and resources, process, management and communication, achievements, and outcomes. The project used a mixed evaluation approach and included Strengths (S, Weaknesses (W, Opportunities (O, and Threats (SWOT analysis. Results: A methodology for longitudinal EU projects’ evaluation is described. The evaluation process allowed to highlight strengths and weaknesses and highlighted good coordination and communication between project partners as well as some key issues such as: the need for a shared glossary covering areas investigated by the project, problematic issues related to the involvement of stakeholders from outside the project, and issues with timing. Numerical SWOT analysis showed improvement in project performance over time. The proportion of participating project partners in the evaluation varied from 100% to 83.3%. Conclusions: There is a need for the implementation of a structured evaluation process in multidisciplinary projects involving different stakeholders in diverse socio-environmental and political conditions. Based on the PATHWAYS experience, a clear monitoring methodology is suggested as essential in every multidisciplinary research projects.

  13. Interdisciplinary Biomathematics: Engaging Undergraduates in Research on the Fringe of Mathematical Biology

    Science.gov (United States)

    Fowler, Kathleen; Luttman, Aaron; Mondal, Sumona

    2013-01-01

    The US National Science Foundation's (NSF's) Undergraduate Biology and Mathematics (UBM) program significantly increased undergraduate research in the biomathematical sciences. We discuss three UBM-funded student research projects at Clarkson University that lie at the intersection of not just mathematics and biology, but also other fields. The…

  14. A Project-Based Biologically-Inspired Robotics Module

    Science.gov (United States)

    Crowder, R. M.; Zauner, K.-P.

    2013-01-01

    The design of any robotic system requires input from engineers from a variety of technical fields. This paper describes a project-based module, "Biologically-Inspired Robotics," that is offered to Electronics and Computer Science students at the University of Southampton, U.K. The overall objective of the module is for student groups to…

  15. The Human Genome Project: Biology, Computers, and Privacy.

    Science.gov (United States)

    Cutter, Mary Ann G.; Drexler, Edward; Gottesman, Kay S.; Goulding, Philip G.; McCullough, Laurence B.; McInerney, Joseph D.; Micikas, Lynda B.; Mural, Richard J.; Murray, Jeffrey C.; Zola, John

    This module, for high school teachers, is the second of two modules about the Human Genome Project (HGP) produced by the Biological Sciences Curriculum Study (BSCS). The first section of this module provides background information for teachers about the structure and objectives of the HGP, aspects of the science and technology that underlie the…

  16. Development and Assessment of Service Learning Projects in General Biology

    Science.gov (United States)

    Felzien, Lisa; Salem, Laura

    2008-01-01

    Service learning involves providing service to the community while requiring students to meet learning goals in a specific course. A service learning project was implemented in a general biology course at Rockhurst University to involve students in promoting scientific education in conjunction with community partner educators. Students were…

  17. Biological and Environmental Research Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Balaji, V. [Princeton Univ., NJ (United States). Earth Science Grid Federation (ESGF); Boden, Tom [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Cowley, Dave [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Dart, Eli [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Dattoria, Vince [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Desai, Narayan [Argonne National Lab. (ANL), Argonne, IL (United States); Egan, Rob [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Foster, Ian [Argonne National Lab. (ANL), Argonne, IL (United States); Goldstone, Robin [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gregurick, Susan [U.S. Dept. of Energy, Washington, DC (United States). Biological Systems Science Division; Houghton, John [U.S. Dept. of Energy, Washington, DC (United States). Biological and Environmental Research (BER) Program; Izaurralde, Cesar [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnston, Bill [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Joseph, Renu [U.S. Dept. of Energy, Washington, DC (United States). Climate and Environmental Sciences Division; Kleese-van Dam, Kerstin [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lipton, Mary [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Monga, Inder [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Pritchard, Matt [British Atmospheric Data Centre (BADC), Oxon (United Kingdom); Rotman, Lauren [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Strand, Gary [National Center for Atmospheric Research (NCAR), Boulder, CO (United States); Stuart, Cory [Argonne National Lab. (ANL), Argonne, IL (United States); Tatusova, Tatiana [National Inst. of Health (NIH), Bethesda, MD (United States); Tierney, Brian [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Thomas, Brian [Univ. of California, Berkeley, CA (United States); Williams, Dean N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Zurawski, Jason [Internet2, Washington, DC (United States)

    2013-09-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy (DOE) Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of SC programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet be a highly successful enabler of scientific discovery for over 25 years. In November 2012, ESnet and the Office of Biological and Environmental Research (BER) of the DOE SC organized a review to characterize the networking requirements of the programs funded by the BER program office. Several key findings resulted from the review. Among them: 1) The scale of data sets available to science collaborations continues to increase exponentially. This has broad impact, both on the network and on the computational and storage systems connected to the network. 2) Many science collaborations require assistance to cope with the systems and network engineering challenges inherent in managing the rapid growth in data scale. 3) Several science domains operate distributed facilities that rely on high-performance networking for success. Key examples illustrated in this report include the Earth System Grid Federation (ESGF) and the Systems Biology Knowledgebase (KBase). This report expands on these points, and addresses others as well. The report contains a findings section as well as the text of the case studies discussed at the review.

  18. 2010 Plant Molecular Biology Gordon Research Conference

    Energy Technology Data Exchange (ETDEWEB)

    Michael Sussman

    2010-07-23

    The Plant Molecular Biology Conference has traditionally covered a breadth of exciting topics and the 2010 conference will continue in that tradition. Emerging concerns about food security have inspired a program with three main themes: (1) genomics, natural variation and breeding to understand adaptation and crop improvement, (2) hormonal cross talk, and (3) plant/microbe interactions. There are also sessions on epigenetics and proteomics/metabolomics. Thus this conference will bring together a range of disciplines, will foster the exchange of ideas and enable participants to learn of the latest developments and ideas in diverse areas of plant biology. The conference provides an excellent opportunity for individuals to discuss their research because additional speakers in each session will be selected from submitted abstracts. There will also be a poster session each day for a two-hour period prior to dinner. In particular, this conference plays a key role in enabling students and postdocs (the next generation of research leaders) to mingle with pioneers in multiple areas of plant science.

  19. The Human Genome Project: big science transforms biology and medicine.

    Science.gov (United States)

    Hood, Leroy; Rowen, Lee

    2013-01-01

    The Human Genome Project has transformed biology through its integrated big science approach to deciphering a reference human genome sequence along with the complete sequences of key model organisms. The project exemplifies the power, necessity and success of large, integrated, cross-disciplinary efforts - so-called 'big science' - directed towards complex major objectives. In this article, we discuss the ways in which this ambitious endeavor led to the development of novel technologies and analytical tools, and how it brought the expertise of engineers, computer scientists and mathematicians together with biologists. It established an open approach to data sharing and open-source software, thereby making the data resulting from the project accessible to all. The genome sequences of microbes, plants and animals have revolutionized many fields of science, including microbiology, virology, infectious disease and plant biology. Moreover, deeper knowledge of human sequence variation has begun to alter the practice of medicine. The Human Genome Project has inspired subsequent large-scale data acquisition initiatives such as the International HapMap Project, 1000 Genomes, and The Cancer Genome Atlas, as well as the recently announced Human Brain Project and the emerging Human Proteome Project.

  20. Division of Biological and Medical Research annual research summary, 1983

    Energy Technology Data Exchange (ETDEWEB)

    Barr, S.H. (ed.)

    1984-08-01

    This research summary contains brief descriptions of research in the following areas: (1) mechanisms of hepatocarcinogenesis; (2) role of metals in cocarcinogenesis and the use of liposomes for metal mobilization; (3) control of mutagenesis and cell differentiation in cultured cells by tumor promoters; (4) radiation effects in mammalian cells; (5) radiation carcinogenesis and radioprotectors; (6) life shortening, tumor induction, and tissue dose for fission-neutron and gamma-ray irradiations; (7) mammalian genetics and biostatistics; (8) radiation toxicity studies; (9) hematopoiesis in chronic toxicity; (10) molecular biology studies; (11) chemical toxicology; (12) carcinogen identification and metabolism; (13) metal metabolism and toxicity; and (14) neurobehavioral chronobiology. (ACR)

  1. Division of Biological and Medical Research annual research summary, 1983

    International Nuclear Information System (INIS)

    Barr, S.H.

    1984-08-01

    This research summary contains brief descriptions of research in the following areas: (1) mechanisms of hepatocarcinogenesis; (2) role of metals in cocarcinogenesis and the use of liposomes for metal mobilization; (3) control of mutagenesis and cell differentiation in cultured cells by tumor promoters; (4) radiation effects in mammalian cells; (5) radiation carcinogenesis and radioprotectors; (6) life shortening, tumor induction, and tissue dose for fission-neutron and gamma-ray irradiations; (7) mammalian genetics and biostatistics; (8) radiation toxicity studies; (9) hematopoiesis in chronic toxicity; (10) molecular biology studies; (11) chemical toxicology; (12) carcinogen identification and metabolism; (13) metal metabolism and toxicity; and (14) neurobehavioral chronobiology

  2. Progress of scientific researches and project of CSR in IMP

    International Nuclear Information System (INIS)

    Jin Genming

    2004-01-01

    The article reviews the recent progress of the scientific researches including synthesis of new nuclides, investigations of the isospin effects in heavy ion collisions, studies of the nuclear structure in high spin states and the applications of heavy ion beams to other scientific researches, such as biology and material science. It also gives a brief introduction of the development of the design and progress of the new project of heavy ion cooling storage ring (CSR) of Lanzhou. (author)

  3. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    International Nuclear Information System (INIS)

    1985-01-01

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division

  4. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division.

  5. Toxicology research projects directory, 1978. Monthly repts

    International Nuclear Information System (INIS)

    1978-01-01

    The Toxicology Research Projects Directory is a monthly publication of ongoing research projects in toxicology and related fields selected from the files of the Smithsonian Science Information Exchange (SSIE). Each issue lists toxicology-related research projects reported to SSIE during the one-month period preceding that issue. Each of the summaries is categorized by scientific discipline and assigned a unique identification number for cross-referencing from the Directory Indexes--Subject, Investigator, Performing Organization, Supporting Agency, and Master Grant Number. The thirteenth issue consists of Cumulative Indexes for the entire volume with referencing to projects in all of the previous twelve issues. The emphasis of the Directory is on the manifestations of the exposure of man and animals to toxic substances. Projects are classified by toxic agents, research orientation, and areas of environmental concern

  6. Summaries of research projects for fiscal years 1996 and 1997, medical applications and biophysical research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    The Medical Applications and Biophysical Research Division of the Office of Biological and Environmental Research supports and manages research in several distinct areas of science and technology. The projects described in this book are grouped by the main budgetary areas: General Life Sciences (structural molecular biology), Medical Applications (primarily nuclear medicine) and Measurement Science (analytical chemistry instrumentation), Environmental Management Science Program, and the Small Business Innovation Research Program. The research funded by this division complements that of the other two divisions in the Office of Biological and Environmental Research (OBER): Health Effects and Life Sciences Research, and Environmental Sciences. Most of the OBER programs are planned and administered jointly by the staff of two or all three of the divisions. This summary book provides information on research supported in these program areas during Fiscal Years 1996 and 1997.

  7. The Learning of Biology: A Structural Basis for Future Research

    Science.gov (United States)

    Murray, Darrel L.

    1977-01-01

    This article reviews recent research studies and experiences relating the learning theories of Ausubel to biology instruction. Also some suggestions are made for future research on the learning of biology. (MR)

  8. Research projects of STUK 2000-2002

    International Nuclear Information System (INIS)

    Salomaa, S.

    2000-06-01

    The primary goal of STUK, the Finnish Radiation and Nuclear Safety Authority, is to prevent and limit the harmful effects of radiation. The research conducted by STUK yields new information related to the use, occurrence and effects of radiation. STUK research projects 2000 - 2002 summarises STUK's own research activities on radiation protection. In addition to these, STUK also supervises and funds research projects related to safety of nuclear energy and nuclear waste and materials that are carried out in other research institutes. Information on the research projects and related publications is also available on STUK's WWW pages at www.stuk.fi. STUK's research focuses on radiation protection and the health effects of radiation. During 2000 - 2002, the main emphasis will be on projects supporting the Finnish national environmental health action plan, the health risks of radiation, emergency preparedness and cooperation with neighbouring CEE areas. EU directives on radiation protection and medical exposure to radiation also influence the course taken by research carried out at STUK. New research priorities also include studies on non-ionising radiation, especially the effects of mobile phone frequency radiation. STUK's research activities are now more international than ever; the institute is involved in about 20 research projects funded by EC. Apart from the European Union and the Nordic countries, STUK's main partners are to be found in Russia, Estonia and the USA. (author)

  9. Research projects of STUK 2000-2002

    Energy Technology Data Exchange (ETDEWEB)

    Salomaa, S. [ed.

    2000-06-01

    The primary goal of STUK, the Finnish Radiation and Nuclear Safety Authority, is to prevent and limit the harmful effects of radiation. The research conducted by STUK yields new information related to the use, occurrence and effects of radiation. STUK research projects 2000 - 2002 summarises STUK's own research activities on radiation protection. In addition to these, STUK also supervises and funds research projects related to safety of nuclear energy and nuclear waste and materials that are carried out in other research institutes. Information on the research projects and related publications is also available on STUK's WWW pages at www.stuk.fi. STUK's research focuses on radiation protection and the health effects of radiation. During 2000 - 2002, the main emphasis will be on projects supporting the Finnish national environmental health action plan, the health risks of radiation, emergency preparedness and cooperation with neighbouring CEE areas. EU directives on radiation protection and medical exposure to radiation also influence the course taken by research carried out at STUK. New research priorities also include studies on non-ionising radiation, especially the effects of mobile phone frequency radiation. STUK's research activities are now more international than ever; the institute is involved in about 20 research projects funded by EC. Apart from the European Union and the Nordic countries, STUK's main partners are to be found in Russia, Estonia and the USA. (author)

  10. Molecular biology approaches in bioadhesion research

    Directory of Open Access Journals (Sweden)

    Marcelo Rodrigues

    2014-07-01

    Full Text Available The use of molecular biology tools in the field of bioadhesion is still in its infancy. For new research groups who are considering taking a molecular approach, the techniques presented here are essential to unravelling the sequence of a gene, its expression and its biological function. Here we provide an outline for addressing adhesion-related genes in diverse organisms. We show how to gradually narrow down the number of candidate transcripts that are involved in adhesion by (1 generating a transcriptome and a differentially expressed cDNA list enriched for adhesion-related transcripts, (2 setting up a BLAST search facility, (3 perform an in situ hybridization screen, and (4 functional analyses of selected genes by using RNA interference knock-down. Furthermore, latest developments in genome-editing are presented as new tools to study gene function. By using this iterative multi-technologies approach, the identification, isolation, expression and function of adhesion-related genes can be studied in most organisms. These tools will improve our understanding of the diversity of molecules used for adhesion in different organisms and these findings will help to develop innovative bio-inspired adhesives.

  11. Advanced energy projects FY 1997 research summaries

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    The mission of the Advanced Energy Projects (AEP) program is to explore the scientific feasibility of novel energy-related concepts that are high risk, in terms of scientific feasibility, yet have a realistic potential for a high technological payoff. The concepts supported by the AEP are typically at an early stage of scientific development. They often arise from advances in basic research and are premature for consideration by applied research or technology development programs. Some are based on discoveries of new scientific phenomena or involve exploratory ideas that span multiple scientific and technical disciplines which do not fit into an existing DOE program area. In all cases, the objective is to support evaluation of the scientific or technical feasibility of the novel concepts involved. Following AEP support, it is expected that each concept will be sufficiently developed to attract further funding from other sources to realize its full potential. Projects that involve evolutionary research or technology development and demonstration are not supported by AEP. Furthermore, research projects more appropriate for another existing DOE research program are not encouraged. There were 65 projects in the AEP research portfolio during Fiscal Year 1997. Eigheen projects were initiated during that fiscal year. This document consists of short summaries of projects active in FY 1997. Further information of a specific project may be obtained by contacting the principal investigator.

  12. Internationalization Measures in Large Scale Research Projects

    Science.gov (United States)

    Soeding, Emanuel; Smith, Nancy

    2017-04-01

    Internationalization measures in Large Scale Research Projects Large scale research projects (LSRP) often serve as flagships used by universities or research institutions to demonstrate their performance and capability to stakeholders and other interested parties. As the global competition among universities for the recruitment of the brightest brains has increased, effective internationalization measures have become hot topics for universities and LSRP alike. Nevertheless, most projects and universities are challenged with little experience on how to conduct these measures and make internationalization an cost efficient and useful activity. Furthermore, those undertakings permanently have to be justified with the Project PIs as important, valuable tools to improve the capacity of the project and the research location. There are a variety of measures, suited to support universities in international recruitment. These include e.g. institutional partnerships, research marketing, a welcome culture, support for science mobility and an effective alumni strategy. These activities, although often conducted by different university entities, are interlocked and can be very powerful measures if interfaced in an effective way. On this poster we display a number of internationalization measures for various target groups, identify interfaces between project management, university administration, researchers and international partners to work together, exchange information and improve processes in order to be able to recruit, support and keep the brightest heads to your project.

  13. Contribution to researches in biophysics and biology

    International Nuclear Information System (INIS)

    Luccioni, Catherine

    2000-01-01

    In this accreditation to supervise research, the author indicates its curriculum and scientific works which mainly dealt with the different agents used in chemotherapy. Scientific works addressed anti-carcinogenic pharmacology, applied biophysics, and researches in oncology and radiobiology. Current research projects deal with mechanisms of cellular transformation and the implication of the anti-oxidising metabolism and of nucleotide metabolism in cell radio-sensitivity. Teaching and research supervising activities are also indicated. Several articles are proposed in appendix: Average quality factor and dose equivalent meter based on microdosimetry techniques; Activity of thymidylate synthetase, thymidine kinase and galactokinase in primary and xenografted human colorectal cancers in relation to their chromosomal patterns; Nucleotide metabolism in human gliomas, relation to the chromosomal profile; Pyrimidine nucleotide metabolism in human colon carcinomas: comparison of normal tissues, primary tumors and xenografts; Modifications of the antioxidant metabolism during proliferation and differentiation of colon tumours cell lines; Modulation of the antioxidant enzymes, p21 and p53 expression during proliferation and differentiation of human melanoma cell lines; Purine metabolism in 2 human melanoma cell lines, relation with proliferation and differentiation; Radiation-induced changes in nucleotide metabolism of 2 colon cancer cell lines with different radio-sensitivities

  14. Advanced energy projects: FY 1987 research summaries

    International Nuclear Information System (INIS)

    1987-09-01

    This report contains brief summaries of all projects active in the Division of Advanced Energy Projects during Fiscal Year 1987 (October 1, 1986-September 30, 1987). The intent of this compilation is to provide a convenient means for quickly acquainting an interested reader with the program in Advanced Energy Projects. More detailed information on research activities in a particular project may be obtained by contacting directly the principal investigator. Some projects will have reached the end of their contract periods by the time this book appears, and will, therefore, no longer be active. Those cases in which work was completed in FY '87 are indicated by the footnote: Project completed. The annual funding level of each project is shown

  15. Research projects of STUK 2003-2005

    International Nuclear Information System (INIS)

    Salomaa, S.

    2004-01-01

    The primary goal of STUK, Finnish Radiation and Nuclear Safety Authority, is to protect man, society, environment and future generations from the harmful effects of radiation. The research conducted by STUK yields new information related to the use, occurrence and effects of radiation. STUK research projects 2003 - 2005 summarizes STUK's own research activities on radiation protection. In addition to these, STUK also supervises and funds research projects related to safety of nuclear energy, and nuclear waste and materials that are carried out in other research institutes. Information on the research projects and related publications is also available on STUK's WWW pages at www.stuk.fi. STUK's research focuses on radiation protection and health effects of radiation. During 2003 - 2005 the main emphasis will be on research supporting the Finnish national environmental health action plan, and projects concerning the health risks of radiation, nuclear emergency preparedness and protection of biota. EU directives on radiation protection and medical radiation exposure also influence the course taken by the research carried out at STUK. New research priorities also include studies on non-ionising radiation, especially the effects of mobile phone frequency radiation. STUK's research networks involve well over 100 national and international partners. During 2003 - 2005 STUK is actively participating in the 6th framework research programmes of EC

  16. 'Ethiopia-Netherlands AIDS research project'

    NARCIS (Netherlands)

    Sanders, E. J.; Rinke de Wit, T. F.; Fontanet, A. L.; Goudsmit, J.; Miedema, F.; Coutinho, R. A.

    2001-01-01

    The 'Ethiopia-Netherlands AIDS Research Project' (ENARP), started in 1994, is a long-term collaboration between AIDS researchers in Amsterdam and the Ethiopian Health and Nutrition Research Institute in Addis Ababa. The ENARP's primary objectives include conducting studies on HIV and AIDS in

  17. Leading Edge Aeronautics Research for NASA Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The LEARN Project explores the creation of novel concepts and processes with the potential to create new capabilities in aeronautics research through awards to the...

  18. STUK research projects 1998-2000

    International Nuclear Information System (INIS)

    Salomaa, S.; Eloranta, E.; Heimbuerger, H.; Jokela, K.; Jaervinen, H.

    1998-07-01

    The primary goal of STUK, the Finnish Radiation and Nuclear Safety Authority, is to prevent and limit the harmful effects of radiation. The research conducted by STUK yields new information related to the use, occurrence and effects of radiation and promotes the supervision of nuclear safety. STUK research projects 1998 - 2000 summarizes STUK's own research projects and commissioned research designed to promote the supervision of nuclear safety. Information on the research projects and related publications is also available on STUK's WWW pages at www.stuk.fi. The work done on the safe use of nuclear power and nuclear waste management mainly comprises commissioned research projects which derive from the needs of authorities, and are funded and directed by STUK. This research is conducted by organizations outside STUK, but supervised by STUK experts. In some cases, STUK personnel are also involved. The goal of this research work is to produce the information needed for decision-making, to develop supervisory methods and to ensure that recent developments in science and technology are taken into account in action to promote safe use of nuclear power. STUK's own research focuses on radiation protection and the health effects of radiation. During 1998 - 2000, the main emphasis will be on projects supporting the Finnish national environmental health action plan, the health risks of radiation, emergency preparedness and cooperation with neighbouring CEE areas. EU directives on radiation protection and medical exposure to radiation also influence the course taken by research carried out at STUK. STUK's research activities are now more international than ever; the institute is involved in more then 20 research projects funded by EU. Apart from the EU and the Nordic countries, STUK's main partners are to be found in Russia, Estonia and the USA. (orig.)

  19. Biological research for the radiation protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Chan Kug; Shim, Hae Won; Jung, Il Lae; Byun, Hee Sun; Moon, Myung Sook; Cho, Hye Jeong; Kim, Jin Sik

    2003-04-01

    The work scope of 'Biological Research for the Radiation Protection' had contained the research about polyamine effect on cell death triggered ionizing radiation, H 2 O 2 and toxic agents. In this paper, to elucidate the role of polyamines as mediator in lysosomal damage and stress(H 2 O 2 )- induced apoptosis, we utilized α-DiFluoroMethylOrnithine (DFMO), which inhibited ornithine decarboxylase and depleted intracellular putrescine, and investigated the effects of polyamine on the apoptosis caused by H 2 O 2 , ionizing radiation and paraquat. We also showed that MGBG, inhibitor of polyamine biosynthesis, treatment affected intracellular redox steady states, intracellular ROS levels and protein oxidation. Thereafter we also investigated whether MGBG may enhance the cytotoxic efficacy of tumor cells caused by ionizing radiation or H 2 O 2 because such compounds are able to potentiate the cell-killing effects. In addition, ceruloplasmin and thioredoxin, possible antioxidant proteins, were shown to have protective effect on radiation- or H 2 O 2 (or chemicals)-induced macromolecular damage or cell death

  20. Prototype Biology-Based Radiation Risk Module Project

    Science.gov (United States)

    Terrier, Douglas; Clayton, Ronald G.; Patel, Zarana; Hu, Shaowen; Huff, Janice

    2015-01-01

    Biological effects of space radiation and risk mitigation are strategic knowledge gaps for the Evolvable Mars Campaign. The current epidemiology-based NASA Space Cancer Risk (NSCR) model contains large uncertainties (HAT #6.5a) due to lack of information on the radiobiology of galactic cosmic rays (GCR) and lack of human data. The use of experimental models that most accurately replicate the response of human tissues is critical for precision in risk projections. Our proposed study will compare DNA damage, histological, and cell kinetic parameters after irradiation in normal 2D human cells versus 3D tissue models, and it will use a multi-scale computational model (CHASTE) to investigate various biological processes that may contribute to carcinogenesis, including radiation-induced cellular signaling pathways. This cross-disciplinary work, with biological validation of an evolvable mathematical computational model, will help reduce uncertainties within NSCR and aid risk mitigation for radiation-induced carcinogenesis.

  1. Scientific projection paper for space radiobiological research

    International Nuclear Information System (INIS)

    Vinograd, S.P.

    1980-01-01

    A nationale for the radiobiological research requirements for space is rooted in a national commitment to the exploration of space, mandated in the form of the National Space Act. This research is almost entirely centered on man; more specifically, on the effects of the space radiation environment on man and his protection from them. The research needs discussed in this presentation include the space radiation environment; dosimetry; radiation biology-high LET particles (dose/response); and operational countermeasures

  2. Research progress on space radiation biology

    International Nuclear Information System (INIS)

    Li Wenjian; Dang Bingrong; Wang Zhuanzi; Wei Wei; Jing Xigang; Wang Biqian; Zhang Bintuan

    2010-01-01

    Space radiation, particularly induced by the high-energy charged particles, may cause serious injury on living organisms. So it is one critical restriction factor in Manned Spaceflight. Studies have shown that the biological effects of charged particles were associated with their quality, the dose and the different biological end points. In addition, the microgravity conditions may affect the biological effects of space radiation. In this paper we give a review on the biological damage effects of space radiation and the combined biological effects of the space radiation coupled with the microgravity from the results of space flight and ground simulation experiments. (authors)

  3. Radiation chemistry in development and research of radiation biology

    International Nuclear Information System (INIS)

    Min Rui

    2010-01-01

    During the establishment and development of radiation biology, radiation chemistry acts like bridge which units the spatial and temporal insight coming from radiation physics with radiation biology. The theory, model, and methodology of radiation chemistry play an important role in promoting research and development of radiation biology. Following research development of radiation biology effects towards systems radiation biology the illustration and exploration both diversity of biological responses and complex process of biological effect occurring remain to need the theory, model, and methodology come from radiation chemistry. (authors)

  4. Cultural differences in Research project management

    Science.gov (United States)

    Barbier, Michele

    2016-04-01

    Scientific Projects today have increased in complexity, requiring multidisciplinarity, and requiring a mix of diverse individuals from different countries who must be integrated into an effective project. Effective team building is one of the prime responsibilities of the project manager. When the project is supported by a funding, the integration and the implication of the different partners are quite easy. Particularly when partners are developing high-performing teams. However, management of research project requires further skills when the budget is not very high and/or when partners are from non-European countries and are not using the same vocabulary. The various cultures, values, beliefs and social usages, particularly with Mediterranean countries cause a special style of communication for an individual or group of individuals. This communication style participates in the success of the project and encompasses a lot of diplomatic skills which will be highlighted.

  5. Has Modern Biology Entered the Mouth? The Clinical Impact of Biological Research.

    Science.gov (United States)

    Baum, Bruce J.

    1991-01-01

    Three areas of biological research that are beginning to have an impact on clinical medicine are examined, including molecular biology, cell biology, and biotechnology. It is concluded that oral biologists and educators must work cooperatively to bring rapid biological and biomedical advances into dental training in a meaningful way. (MSE)

  6. Integrated Project Delivery (IPD Research Trends.

    Directory of Open Access Journals (Sweden)

    Kahvandi, Z.

    2017-07-01

    Full Text Available Integrated Project Delivery (IPD is introduced as a vibrant approach to enhance project implementation, having particular position in recent studies among construction researchers. This study analyzes the research trends on the field of IPD to provide an appropriate vision for future researchers in this specialized field. While so far no comprehensive research has been done in this field, this study provides a comprehensive review of existing studies through in-depth literature review method. This research evaluates studies conducted in the field of IPD, which is a basis for future researchers to improve conditions of IPD implementation in different countries. For that this study Using library studies, the trend of researches conducted on various concepts and domains during various years, has been investigated. Future studies can simply use the outputs of this research to shape their research flow on establishing continuing progress of IPD. The data obtained from descriptive analyses are illustrated quantitatively, followed by comprehensive analyses and discussion of the results. Moreover, this study concluded that during recent years, the trend of studies conducted about IPD has increased, particularly articles examined challenges. In the next step, more studies have been performed in the field of construction. Those articles are preferred that have evaluated principles, challenges, and solutions for resolving barriers. Proper IPD implementation facilitates enhanced share of information and early identification of stakeholders through a proper timing as vital keys to realize objectives of the construction projects, reduce risks, and increase the chance of project success.

  7. Research project on the thermal pollution of waters

    International Nuclear Information System (INIS)

    Steinlein; Becker

    1977-01-01

    The results of essentially completed and current research and development projects - as far as available in a short time - are explained in the present study, compared and their practicle applicability indicated. The number of publications in the literature index is split up into the single specialist fields as follows: 13% hydrodynamics (propagation caculations, models, measurements); 45% biology-chemistry (effects on micro and macro fauna of waters, on water contents, mathematical models of oxygen balance and biocenosis); 31% hydrometeorology including problems on the thermal economy of the waters as well as special thermal load calculations; 5% heat introduction into ground water; 6% others e.g. use of remote sensing for temperature measurement. The current research projects in the FRG are split up into the following single specialist fields: 16% hydromechanics; 42% biology-chemistry; 24% hydrometeorology including thermal economy; 10% use of ground water; 8% others (almost exclusively problems in connection with the use of remote sensing methods). (orig.) [de

  8. Project management of life-science research projects: project characteristics, challenges and training needs.

    Science.gov (United States)

    Beukers, Margot W

    2011-02-01

    Thirty-four project managers of life-science research projects were interviewed to investigate the characteristics of their projects, the challenges they faced and their training requirements. A set of ten discriminating parameters were identified based on four project categories: contract research, development, discovery and call-based projects--projects set up to address research questions defined in a call for proposals. The major challenges these project managers are faced with relate to project members, leadership without authority and a lack of commitment from the respective organization. Two-thirds of the project managers indicated that they would be interested in receiving additional training, mostly on people-oriented, soft skills. The training programs that are currently on offer, however, do not meet their needs. Copyright © 2010 Elsevier Ltd. All rights reserved.

  9. Division of Biological and Medical Research annual report 1978

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.W. (ed.)

    1978-01-01

    The research during 1978 in the Division of Biological and Medical Research, Argonne National Laboratory, is summarized. Studies related to nuclear energy include responses of beagles to continuous low-level /sup 60/Co gamma radiation, and development of leukemic indicators; comparison of lifetime effects in mice of low-level neutron and /sup 60/Co gamma radiation; genetic effects of high LET radiations; and metabolic and therapeutic studies of heavy metals. Studies of nonnuclear energy sources deal with characterization and toxicological evaluation of effluents of fluidized bed combustion and coal gasification; electrical storage systems; electric fields associated with energy transmission; and development of population projection models and assessment of human risk. Basic research studies include fundamental structural and biophysical investigations; circadian rhythms; mutagenesis in bacteria and mammalian cells; cell killing, damage, and repair in mammalian cells; carcinogenesis and cocarcinogenesis; the use of liposomes as biological carriers; and studies of environmental influences on life-span, physiological performance, and circadian cycles. In the area of medical development, proteins in urine and tissues of normal and diseased humans are analyzed, and advanced analytical procedures for use of stable isotopes in clinical research and diagnosis are developed and applied. The final sections of the report cover support facilities, educational activities, the seminar program, staff talks, and staff publications.

  10. Division of Biological and Medical Research annual report 1978

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1978-01-01

    The research during 1978 in the Division of Biological and Medical Research, Argonne National Laboratory, is summarized. Studies related to nuclear energy include responses of beagles to continuous low-level 60 Co gamma radiation, and development of leukemic indicators; comparison of lifetime effects in mice of low-level neutron and 60 Co gamma radiation; genetic effects of high LET radiations; and metabolic and therapeutic studies of heavy metals. Studies of nonnuclear energy sources deal with characterization and toxicological evaluation of effluents of fluidized bed combustion and coal gasification; electrical storage systems; electric fields associated with energy transmission; and development of population projection models and assessment of human risk. Basic research studies include fundamental structural and biophysical investigations; circadian rhythms; mutagenesis in bacteria and mammalian cells; cell killing, damage, and repair in mammalian cells; carcinogenesis and cocarcinogenesis; the use of liposomes as biological carriers; and studies of environmental influences on life-span, physiological performance, and circadian cycles. In the area of medical development, proteins in urine and tissues of normal and diseased humans are analyzed, and advanced analytical procedures for use of stable isotopes in clinical research and diagnosis are developed and applied. The final sections of the report cover support facilities, educational activities, the seminar program, staff talks, and staff publications

  11. Annual review of research projects 1984

    International Nuclear Information System (INIS)

    Keam, D.W.

    1986-02-01

    This progress report provides a brief outline of current laboratory research and development projects and their present status. Research fields covered are: uranium, radon and its daughters, radiation effects in solids and gases, x-rays and clinical dosimetry, measurement standards in radiation dosimetry, radiopharmaceuticals and nuclear medicine, non-ionizing electromagnetic radiations, environmental radiochemistry and radiation monitoring

  12. Annual review of research projects 1983

    International Nuclear Information System (INIS)

    1985-08-01

    This progress report provides a brief outline of current laboratory research and development projects and their present status. Research fields covered are: uranium, radon and its daughters, radiation effects in solids and gases, thermoluminescence, x-rays and clinical dosimetry, measurement standards in radiation dosimetry, radiopharmaceuticals and nuclear medicine, radionuclide metrology, non-ionizing electromagnetic radiations, environmental radiochemistry and radiation monitoring

  13. Jmol-Enhanced Biochemistry Research Projects

    Science.gov (United States)

    Saderholm, Matthew; Reynolds, Anthony

    2011-01-01

    We developed a protein research project for a one-semester biochemistry lecture class to enhance learning and more effectively train students to understand protein structure and function. During this semester-long process, students select a protein with known structure and then research its structure, sequence, and function. This project…

  14. Research oriented projects on design themese

    DEFF Research Database (Denmark)

    Tollestrup, Christian; Eriksen, Kaare; Ovesen, Nis

    2011-01-01

    How can design students do research-oriented projects about design themes? At the 3rd semester at the Industrial Design Master Program at Aalborg University this is done by taking research oriented learning objectives on design theories and methods and combining them with experimental case studie...... and professional self-reflection amongst students are improved....

  15. Cross-disciplinary, authentic student research projects

    NARCIS (Netherlands)

    Heck, A.; Uylings, P.; Kędzierska, E.; Ellermeijer, T.

    2010-01-01

    In the Dutch secondary education system, students must carry out at the end of their school career a rather large research or design project to demonstrate their ability to apply acquired knowledge and skills while pursuing a research question or design goal in some depth. They are encouraged to

  16. Methodology of impact assessment of research projects

    International Nuclear Information System (INIS)

    Rodriguez Cardona, R.; Cobas Aranda, M.

    2014-01-01

    In the context of the management of research projects development it is necessary to have tools to monitor and evaluate progress and the performance of the projects, as well as their results and the impact on society (international agencies of the United Nations and the States 2002 and 2005 Paris Declaration), with the objective of to ensure their contribution to the social and economic development of countries. Many organizations, agencies and Governments apply different methodologies (IDB, World Bank, UNDP, ECLAC, UNESCO; UNICEF, Canada, Japan, other) for these purposes. In the results-based project management system not only paramount is the process or product itself, but also the result or impact of the project (if the program/project produced the effects desired persons, households and institutions and whether those effects are attributable to the intervention of the program / project). The work shows a methodology that allows for a qualitative and quantitative evaluation of impact of research projects and has been result of experience in project management of international collaboration with the International Agency for Atomic Energy (IAEA) and the Cuban Nuclear programme. (author)

  17. Research program on the biological effects of oil pollution

    International Nuclear Information System (INIS)

    Barrett, R.T.

    1991-12-01

    A national research program on the biological effects of oil pollution (FOBO) was initiated by the Norwegian Ministry of Environment in October 1983 in the light of the increasing oil exploration and production activity in the North Sea and northern Norwegian waters. Ambitions were high and five main fields of research were suggested: Seabirds, fish (incl. salmon), marine mammals, the littoral zone and plankton. However, due to the lack of interest on the part of other potential financers, e.g. the Ministry of Fisheries and the oil companies, to participate, the four-year programme had to be limited to the following three topics: Seabirds around bruding colonies and at sea; Higher plants along the shoreline; The littoral zone. The program ran from the autumn of 1985 to the end of 1989 and this report summarizes the main results and conclusions of each project. 95 refs., 52 figs., 9 tabs

  18. BCTR: Biological and Chemical Technologies Research 1994 annual summary report

    Energy Technology Data Exchange (ETDEWEB)

    Petersen, G.

    1995-02-01

    The annual summary report presents the fiscal year (FY) 1994 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). Although the OIT was reorganized in 1991 and AICD no longer exists, this document reports on efforts conducted under the former structure. The annual summary report for 1994 (ASR 94) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization, selected technical and programmatic highlights for 1994; detailed descriptions of individual projects; a listing of program output, including a bibliography of published work; patents, and awards arising from work supported by BCTR.

  19. pClone: Synthetic Biology Tool Makes Promoter Research Accessible to Beginning Biology Students

    Science.gov (United States)

    Campbell, A. Malcolm; Eckdahl, Todd; Cronk, Brian; Andresen, Corinne; Frederick, Paul; Huckuntod, Samantha; Shinneman, Claire; Wacker, Annie; Yuan, Jason

    2014-01-01

    The "Vision and Change" report recommended genuine research experiences for undergraduate biology students. Authentic research improves science education, increases the number of scientifically literate citizens, and encourages students to pursue research. Synthetic biology is well suited for undergraduate research and is a growing area…

  20. Light water reactor safety research project

    International Nuclear Information System (INIS)

    Markoczy, G.; Aksan, S.N.; Behringer, K.; Prodan, M.; Stierli, F.; Ullrich, G.

    1980-07-01

    The research and development activities for the safety of Light Water Power Reactors carried out 1979 at the Swiss Federal Institute for Reactor Research are described. Considerations concerning the necessity, objectives and size of the Safety Research Project are presented, followed by a detailed discussion of the activities in the five tasks of the program, covering fracture mechanics and nondestructive testing, thermal-hydraulics, reactor noise analysis and pressure vessel steel surveillance. (Auth.)

  1. Nuclear safety research project. Annual report 1995

    International Nuclear Information System (INIS)

    Hueper, R.

    1996-08-01

    The reactor safety R and D work of the Karlsruhe Research Centre (FZK) has been part of the Nuclear Safety Research Project (PSF) since 1990. The present annual report 1995 summarizes the R and D results. The research tasks are coordinated in agreement with internal and external working groups. The contributions to this report correspond to the status of early 1996. An abstract in English precedes each of them, whenever the respective article is written in German. (orig.) [de

  2. Are Project Developers Knights and Researchers Queens?

    DEFF Research Database (Denmark)

    Vinstrup, Anya Bjørn

    2014-01-01

    How do project developers at universities view their customers – the researchers, and how do they see themselves as a profession? Does this view influence their motivation and what challenges does it impose? Taking elements of theory from Public Service Motivation (PSM) and linking it with a small...... empirically based survey among the project developers at a centrally located office at a university in Denmark – these questions are sought to be answered. The focal point being the motivation of the project developer, with special emphasis on their user perception, and the practical implications it has...... for leadership and organisational structures....

  3. Infusing Bioinformatics and Research-Like Experience into a Molecular Biology Laboratory Course

    Science.gov (United States)

    Nogaj, Luiza A.

    2014-01-01

    A nine-week laboratory project designed for a sophomore level molecular biology course is described. Small groups of students (3-4 per group) choose a tumor suppressor gene (TSG) or an oncogene for this project. Each group researches the role of their TSG/oncogene from primary literature articles and uses bioinformatics engines to find the gene…

  4. Bio Diesel Cellulosic Ethanol Research Project

    Energy Technology Data Exchange (ETDEWEB)

    Hanlon, Edward A. [County of Hendry, FL (United States); Capece, John C. [County of Hendry, FL (United States); McAvoy, Eugene [County of Hendry, FL (United States); Hodges, Alan Wayne [County of Hendry, FL (United States); Shukla, Sanjay [County of Hendry, FL (United States); Ozores-Hamilton, Monica [County of Hendry, FL (United States); Gilbert, Rob [County of Hendry, FL (United States); Wright, Alan [County of Hendry, FL (United States); Baucum, L. [County of Hendry, FL (United States)

    2017-02-07

    The objective of the project is to create the Hendry County Sustainable Biofuels Center and initiate its research, development, and education programs. The mission is to develop engineering and economic assessment methods to evaluate the natural resources impacts of biomass farming and fuel conversion systems; provide sustainability assessments of specific biofuels productions proposals; develop biomass farming and fuel conversion systems that are compatible with south Florida ecosystem restoration priorities; create ecosystem services opportunities and structures to diversify farm income; monitor the range of research and development activities necessary to the creation of sutstainable biofuels production systems in south Florida, identify gaps in the regional research, and assist in the development and coordination of additional projects to fill out the required knowledge base; prepare the workforce of southwest Florida for employment in biofuels related professions; and assist businesses & governmental design and realize sustainable biofuels projects.

  5. Plant biology research and training for the 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, K. [ed.

    1992-12-31

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  6. Plant biology research and training for the 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, K. (ed.)

    1992-01-01

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  7. U1/U2 crib groundwater biological treatment demonstration project

    International Nuclear Information System (INIS)

    Koegler, S.S.; Brouns, T.M.; Heath, W.O.

    1989-11-01

    The primary objective of the biological treatment project is to develop and demonstrate a process for Hanford groundwater remediation. Biodenitrification using facultative anaerobic microorganisms is a promising technology for the simultaneous removal of nitrates and organics from contaminated aqueous streams. During FY 1988, a consortium of Hanford groundwater microorganisms was shown to degrade both nitrates and carbon tetrachloride (CC1 4 ). A pilot-scale treatment system was designed and constructed based on the results of laboratory-and-bench-scale testing. This report summarizes the results of biological groundwater treatment studies performed during FY 1989 at the pilot-scale. These tests were conducted using a simulated Hanford groundwater with a continuous stirred-tank bioreactor, and a fluidized-bed bioreactor that was added to the pilot-scale treatment system in FY 1989. The pilot-scale system demonstrated continuous degradation of nitrates and CC1 4 in a simulated groundwater. 4 refs., 7 figs., 1 tab

  8. Advanced energy projects FY 1994 research summaries

    International Nuclear Information System (INIS)

    1994-09-01

    The Division of Advanced Energy Projects (AEP) provides support to explore the feasibility of novel, energy-related concepts that evolve from advances in basic research. These concepts are typically at an early stage of scientific definition and, therefore, are premature for consideration by applied research or technology development programs. The AEP also supports high-risk, exploratory concepts that do not readily fit into a program area but could have several applications that may span scientific disciplines or technical areas. Projects supported by the Division arise from unsolicited ideas and concepts submitted by researchers. The portfolio of projects is dynamic and reflects the broad role of the Department in supporting research and development for improving the Nation's energy outlook. FY 1994 projects include the following topical areas: novel materials for energy technology; renewable and biodegradable materials; exploring uses of new scientific discoveries; alternate pathways to energy efficiency; alternative energy sources; and innovative approaches to waste treatment and reduction. Summaries are given for 66 projects

  9. Center for Biologics Evaluation and Research (CBER)

    Data.gov (United States)

    Federal Laboratory Consortium — CBER is the Center within FDA that regulates biological products for human use under applicable federal laws, including the Public Health Service Act and the Federal...

  10. Postharvest biology and technology research and development ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-09-03

    Sep 3, 2008 ... The applications of biological control agents in pre- and post-harvest operations and .... production, with regards to food safety, operator health and the ... and to work out sustainable compliance modalities for small-scale ...

  11. Cumulative biological impacts framework for solar energy projects in the California Desert

    Science.gov (United States)

    Davis, Frank W.; Kreitler, Jason R.; Soong, Oliver; Stoms, David M.; Dashiell, Stephanie; Hannah, Lee; Wilkinson, Whitney; Dingman, John

    2013-01-01

    This project developed analytical approaches, tools and geospatial data to support conservation planning for renewable energy development in the California deserts. Research focused on geographical analysis to avoid, minimize and mitigate the cumulative biological effects of utility-scale solar energy development. A hierarchical logic model was created to map the compatibility of new solar energy projects with current biological conservation values. The research indicated that the extent of compatible areas is much greater than the estimated land area required to achieve 2040 greenhouse gas reduction goals. Species distribution models were produced for 65 animal and plant species that were of potential conservation significance to the Desert Renewable Energy Conservation Plan process. These models mapped historical and projected future habitat suitability using 270 meter resolution climate grids. The results were integrated into analytical frameworks to locate potential sites for offsetting project impacts and evaluating the cumulative effects of multiple solar energy projects. Examples applying these frameworks in the Western Mojave Desert ecoregion show the potential of these publicly-available tools to assist regional planning efforts. Results also highlight the necessity to explicitly consider projected land use change and climate change when prioritizing areas for conservation and mitigation offsets. Project data, software and model results are all available online.

  12. Research reactor job analysis - A project description

    International Nuclear Information System (INIS)

    Yoder, John; Bessler, Nancy J.

    1988-01-01

    Addressing the need of the improved training in nuclear industry, nuclear utilities established training program guidelines based on Performance-Based Training (PBT) concepts. The comparison of commercial nuclear power facilities with research and test reactors owned by the U.S. Department of Energy (DOE), made in an independent review of personnel selection, training, and qualification requirements for DOE-owned reactors pointed out that the complexity of the most critical tasks in research reactors is less than that in power reactors. The U.S. Department of Energy (DOE) started a project by commissioning Oak Ridge Associated Universities (ORAU) to conduct a job analysis survey of representative research reactor facilities. The output of the project consists of two publications: Volume 1 - Research Reactor Job Analysis: Overview, which contains an Introduction, Project Description, Project Methodology,, and. An Overview of Performance-Based Training (PBT); and Volume 2 - Research Reactor Job Analysis: Implementation, which contains Guidelines for Application of Preliminary Task Lists and Preliminary Task Lists for Reactor Operators and Supervisory Reactor Operators

  13. Accelerating cancer systems biology research through Semantic Web technology.

    Science.gov (United States)

    Wang, Zhihui; Sagotsky, Jonathan; Taylor, Thomas; Shironoshita, Patrick; Deisboeck, Thomas S

    2013-01-01

    Cancer systems biology is an interdisciplinary, rapidly expanding research field in which collaborations are a critical means to advance the field. Yet the prevalent database technologies often isolate data rather than making it easily accessible. The Semantic Web has the potential to help facilitate web-based collaborative cancer research by presenting data in a manner that is self-descriptive, human and machine readable, and easily sharable. We have created a semantically linked online Digital Model Repository (DMR) for storing, managing, executing, annotating, and sharing computational cancer models. Within the DMR, distributed, multidisciplinary, and inter-organizational teams can collaborate on projects, without forfeiting intellectual property. This is achieved by the introduction of a new stakeholder to the collaboration workflow, the institutional licensing officer, part of the Technology Transfer Office. Furthermore, the DMR has achieved silver level compatibility with the National Cancer Institute's caBIG, so users can interact with the DMR not only through a web browser but also through a semantically annotated and secure web service. We also discuss the technology behind the DMR leveraging the Semantic Web, ontologies, and grid computing to provide secure inter-institutional collaboration on cancer modeling projects, online grid-based execution of shared models, and the collaboration workflow protecting researchers' intellectual property. Copyright © 2012 Wiley Periodicals, Inc.

  14. Designing and Conducting Health Systems Research Projects ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Home · Resources · Publications. Designing and Conducting Health Systems Research Projects Volume 1: Proposal Development and Fieldwork ... IDRC and the United Kingdom's Global AMR Innovation Fund—managed by the ... New website will help record vital life events to improve access to services for all.

  15. Using Replication Projects in Teaching Research Methods

    Science.gov (United States)

    Standing, Lionel G.; Grenier, Manuel; Lane, Erica A.; Roberts, Meigan S.; Sykes, Sarah J.

    2014-01-01

    It is suggested that replication projects may be valuable in teaching research methods, and also address the current need in psychology for more independent verification of published studies. Their use in an undergraduate methods course is described, involving student teams who performed direct replications of four well-known experiments, yielding…

  16. Application of the selected physical methods in biological research

    Directory of Open Access Journals (Sweden)

    Jaromír Tlačbaba

    2013-01-01

    Full Text Available This paper deals with the application of acoustic emission (AE, which is a part of the non-destructive methods, currently having an extensive application. This method is used for measuring the internal defects of materials. AE has a high potential in further research and development to extend the application of this method even in the field of process engineering. For that matter, it is the most elaborate acoustic emission monitoring in laboratory conditions with regard to external stimuli. The aim of the project is to apply the acoustic emission recording the activity of bees in different seasons. The mission is to apply a new perspective on the behavior of colonies by means of acoustic emission, which collects a sound propagation in the material. Vibration is one of the integral part of communication in the community. Sensing colonies with the support of this method is used for understanding of colonies biological behavior to stimuli clutches, colony development etc. Simulating conditions supported by acoustic emission monitoring system the illustrate colonies activity. Collected information will be used to represent a comprehensive view of the life cycle and behavior of honey bees (Apis mellifera. Use of information about the activities of bees gives a comprehensive perspective on using of acoustic emission in the field of biological research.

  17. Data management and data enrichment for systems biology projects.

    Science.gov (United States)

    Wittig, Ulrike; Rey, Maja; Weidemann, Andreas; Müller, Wolfgang

    2017-11-10

    Collecting, curating, interlinking, and sharing high quality data are central to de.NBI-SysBio, the systems biology data management service center within the de.NBI network (German Network for Bioinformatics Infrastructure). The work of the center is guided by the FAIR principles for scientific data management and stewardship. FAIR stands for the four foundational principles Findability, Accessibility, Interoperability, and Reusability which were established to enhance the ability of machines to automatically find, access, exchange and use data. Within this overview paper we describe three tools (SABIO-RK, Excemplify, SEEK) that exemplify the contribution of de.NBI-SysBio services to FAIR data, models, and experimental methods storage and exchange. The interconnectivity of the tools and the data workflow within systems biology projects will be explained. For many years we are the German partner in the FAIRDOM initiative (http://fair-dom.org) to establish a European data and model management service facility for systems biology. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  18. Outline of criticality safety research project

    International Nuclear Information System (INIS)

    Kobayashi, Iwao; Tachimori, Shoichi; Suzaki, Takenori; Takeshita, Isao; Miyoshi, Yoshinori; Nakajima, Ken; Sakurai, Satoshi; Yanagisawa, Hiroshi

    1987-01-01

    As the power generation capacity of LWRs in Japan increased, the establishment and development of nuclear fuel cycle have become the important subject. Conforming to the safety research project of the nation, the Japan Atomic Energy Research Institute has advanced the project of constructing a new research facility, that is, Nuclear Fuel Cycle Engineering Research Facility (NUCEF). In this facility, it is planned to carry out the research on criticality safety, upgraded reprocessing techniques, and the treatment and disposal of transuranium element wastes. In this paper, the subjects of criticality safety research and the research carried out with a criticality safety experiment facility which is expected to be installed in the NUCEF are briefly reported. The experimental data obtained from the criticality safety handbooks and published literatures in foreign countries are short of the data on the mixture of low enriched uranium and plutonium which is treated in the reprocessing of spent fuel from LWRs. The acquisition of the criticality data for various forms of fuel, the elucidation of the scenario of criticality accidents, and the soundness of the confinement system for gaseous fission products and plutonium are the main subjects. The Static Criticality Safety Facility, Transient Criticality Safety Facility and pulse column system are the main facilities. (Kako, I.)

  19. A comprehensive crop genome research project: the Superhybrid Rice Genome Project in China.

    Science.gov (United States)

    Yu, Jun; Wong, Gane Ka-Shu; Liu, Siqi; Wang, Jian; Yang, Huanming

    2007-06-29

    In May 2000, the Beijing Institute of Genomics formally announced the launch of a comprehensive crop genome research project on rice genomics, the Chinese Superhybrid Rice Genome Project. SRGP is not simply a sequencing project targeted to a single rice (Oryza sativa L.) genome, but a full-swing research effort with an ultimate goal of providing inclusive basic genomic information and molecular tools not only to understand biology of the rice, both as an important crop species and a model organism of cereals, but also to focus on a popular superhybrid rice landrace, LYP9. We have completed the first phase of SRGP and provide the rice research community with a finished genome sequence of an indica variety, 93-11 (the paternal cultivar of LYP9), together with ample data on subspecific (between subspecies) polymorphisms, transcriptomes and proteomes, useful for within-species comparative studies. In the second phase, we have acquired the genome sequence of the maternal cultivar, PA64S, together with the detailed catalogues of genes uniquely expressed in the parental cultivars and the hybrid as well as allele-specific markers that distinguish parental alleles. Although SRGP in China is not an open-ended research programme, it has been designed to pave a way for future plant genomics research and application, such as to interrogate fundamentals of plant biology, including genome duplication, polyploidy and hybrid vigour, as well as to provide genetic tools for crop breeding and to carry along a social burden-leading a fight against the world's hunger. It began with genomics, the newly developed and industry-scale research field, and from the world's most populous country. In this review, we summarize our scientific goals and noteworthy discoveries that exploit new territories of systematic investigations on basic and applied biology of rice and other major cereal crops.

  20. SAIL Panama Canal Zone Project 2008 : Biological Survey of Panama (1910-1912)

    OpenAIRE

    DeHart, Liz; Haas, Stephanie C.; Walton, Jennifer; Heil, Kathy

    2009-01-01

    During the 18th Annual 2008 SAIL meeting at the Smithsonian Tropical Research Institute in Panama, a suggestion was made for the need to digitize and make available through the Aquatic Commons some of the early documents related to the U.S. biological survey of Panama from 1910 to 1912. With SAIL’s endeavor, a new digital project was born and this presentation describes its process, beginning to final product. The main source consulted for determining copyright clear publications was: ...

  1. Project for a renewable energy research centre

    Directory of Open Access Journals (Sweden)

    Andrea Giachetta

    2011-04-01

    Full Text Available In Liguria, where sustainable approaches to the design, construction and management of buildings enjoy scant currency, the idea of a company from Milan (FERA s.r.l. setting up a research centre for studies into renewable energy resources, could well open up very interesting development opportunities.The project includes: environmental rehabilitation (restoration projects; strategies for the protection of water resources and waste management systems; passive and active solar systems (solar thermal and experiments with thermodynamic solar energy; hyperinsulation systems, passive cooling of buildings; use of natural materials; bio-climatic use of vegetation. The author describes the project content within the context of the multidisciplinary work that has gone into it.

  2. Research Collaboration Workshop for Women in Mathematical Biology

    CERN Document Server

    Miller, Laura

    2017-01-01

    Inspired by the Research Collaboration Workshop for Women in Mathematical Biology, this volume contains research and review articles that cover topics ranging from models of animal movement to the flow of blood cells in the embryonic heart. Hosted by the National Institute for Mathematics and Biological Synthesis (NIMBioS), the workshop brought together women working in biology and mathematics to form four research groups that encouraged multidisciplinary collaboration and lifetime connections in the STEM field. This volume introduces many of the topics from the workshop, including the aerodynamics of spider ballooning; sleep, circadian rhythms, and pain; blood flow regulation in the kidney; and the effects of antimicrobial therapy on gut microbiota and microbiota and Clostridium difficile. Perfect for students and researchers in mathematics and biology, the papers included in this volume offer an introductory glimpse at recent research in mathematical biology. .

  3. Biotechnology by Design: An Introductory Level, Project-Based, Synthetic Biology Laboratory Program for Undergraduate Students.

    Science.gov (United States)

    Beach, Dale L; Alvarez, Consuelo J

    2015-12-01

    Synthetic biology offers an ideal opportunity to promote undergraduate laboratory courses with research-style projects, immersing students in an inquiry-based program that enhances the experience of the scientific process. We designed a semester-long, project-based laboratory curriculum using synthetic biology principles to develop a novel sensory device. Students develop subject matter knowledge of molecular genetics and practical skills relevant to molecular biology, recombinant DNA techniques, and information literacy. During the spring semesters of 2014 and 2015, the Synthetic Biology Laboratory Project was delivered to sophomore genetics courses. Using a cloning strategy based on standardized BioBrick genetic "parts," students construct a "reporter plasmid" expressing a reporter gene (GFP) controlled by a hybrid promoter regulated by the lac-repressor protein (lacI). In combination with a "sensor plasmid," the production of the reporter phenotype is inhibited in the presence of a target environmental agent, arabinose. When arabinose is absent, constitutive GFP expression makes cells glow green. But the presence of arabinose activates a second promoter (pBAD) to produce a lac-repressor protein that will inhibit GFP production. Student learning was assessed relative to five learning objectives, using a student survey administered at the beginning (pre-survey) and end (post-survey) of the course, and an additional 15 open-ended questions from five graded Progress Report assignments collected throughout the course. Students demonstrated significant learning gains (p Biology Laboratory Project enhanced their understanding of molecular genetics. The laboratory project is highly adaptable for both introductory and advanced courses.

  4. Supporting research projects via student workshops

    DEFF Research Database (Denmark)

    Marschall, Max; Schmeck, Michel; Gengnagel, Christoph

    2016-01-01

    As part of a joint research project between the Centre for Information Technology and Architecture (CITA) and te Department for Structural Design and Technology (KET), a one week student workshop was organised at the Royal Danish Academy of Fine Arts (KADK) in Copenhagen. This paper outlines...... the teaching methods applied to reach maximum insight from student interaction, despite the unfamiliarity the students had with the research matter: physical and numeric form-finding for lightweight hybrid structures. Hybrid structures are defined here as combining different components of low stiffness...

  5. Summaries of fiscal year 1994 projects in medical applications and biophysical research

    International Nuclear Information System (INIS)

    1995-04-01

    This report provides information on the research supported in Fiscal Year 1994 by the Medical Applications and Biophysical Research Division of the Office of Health and Environmental Research. A brief statement of the scope of the following areas is presented: dosimetry; measurement science; radiological and chemical physics; structural biology; human genome; and medical applications. Summaries of the research projects in these categories are presented

  6. Summaries of special research project on nuclear fusion 1980

    International Nuclear Information System (INIS)

    Uchida, Taijiro

    1981-09-01

    This is a report of the research project entitled ''Nuclear fusion'', supported by the grant in aid for fusion research from the Ministry of Education in the fiscal year 1980. The research project was started in April, 1980, and comprises the following seventeen subjects of nuclear fusion research. 1) Heavy irradiation effects, 2) plasma-wall interaction, 3) neutronics, 4) welding engineering, 5) science and technology of tritium, 6) biological effects of tritium, 7) diagnostics of high temperature plasma, 8) new lasers, 9) fundamentals of plasma heating, 10) high efficiency energy conversion, 11) theory and computer simulation, 12) superconducting materials, 13) fundamental phenomena of superconductivity, 14) magnet technology, 15) heat transfer and structural engineering, 16) system design, and 17) resources and assessment of fusion energy. 43 summaries concerning reactor materials and plasma-wall interaction, 29 summaries concerning the science, technology and biological effects of tritium, 41 summaries concerning the fundamentals of reactor plasma control, 15 summaries concerning the technology of superconducting magnets, and 14 summaries concerning the design of fusion reactors and its evaluation are collected in this report, and their results and progress can be known. (Kako, I.)

  7. Enhancing Scientific Inquiry Literacy of Prospective Biology Teachers through Inquiry Lab Project in Microbiology

    Science.gov (United States)

    Kusnadi, K.; Rustaman, N. Y.; Redjeki, S.; Aryantha, I. N. P.

    2017-09-01

    The implementation of the inquiry laboratory based project to enhance scientific inquiry literacy of prospective biology teachers in Microbiology course has been done. The inquiry lab based project was designed by three stages were debriefing of basic microbiology lab skills, guided inquiry and free inquiry respectively. The Study was quasi experimental with control group pretest-posttest design. The subjects were prospective biology teachers consists of 80 students. The scientific inquiry literacy instrument refers to ScInqLiT by Wenning. The results showed that there was significant difference of scientific inquiry literacy posttest scores between experiment and control (α 0,05) and was obtained N-gain score was 0.49 (medium) to experiment and 0.24 (low) to control. Based on formative assessment showed that development of student’s scientific attitude, research and microbiology lab skills during conducting project were increased. Student’s research skills especially in identification of variables, constructing a hypothesis, communicating and concluding were increased. During implementation of inquiry project also showed that they carried out mind and hands-on and so collaborative group investigation lab activities. Our findings may aid in reforming higher-education, particularly in microbiology laboratory activities to better promote scientific inquiry literacy, scientific attitude, research and laboratory skills.

  8. Evaluation of combustion experiments conducted during the research and development project ``Mechanical-biological waste conditioning in combination with thermal processing of partial waste fractions``; Auswertung der Verbrennungsversuche zum Forschungs- und Entwicklungsvorhaben ``mechanisch-biologische Restmuellbehandlung unter Einbindung thermischer Verfahren fuer Teilfraktionen``

    Energy Technology Data Exchange (ETDEWEB)

    Jager, J.; Lohf, A.; Herr, C. [Institut WAR, Darmstadt (Germany)

    1998-12-31

    The technical code on municipal waste makes specific demands on waste to be deposited at landfills which can only be met if mechanical-biological conditioning of waste as well as thermal processing of partial waste fractions are continued also in the future. But waste that has undergone mechanical or mechanical-biological conditioning presents different combustion properties from those of unconditioned waste. In this second stage of the research project, the thermal processability of waste having undergone mechanical or mechanical-biological conditioning was studied. Together with the results from the first project stage, where the throughput represented exclusively mechanically conditioned material, the results of the latter measuring campaigns comprehensively demonstrate possibilities for the thermal processing of partial waste fractions having undergone biological-mechanical conditioning, and inform on changes in plant performance. (orig.) [Deutsch] Um die in der TA-Siedlungsabfall an den abzulagernden Restmuell gestellten Deponieeingangsbedingungen zu erfuellen, muss neben einer mechanisch-biologischen Aufbereitung bei Teilfraktionen auch weiterhin eine thermische Behandlung eingeplant werden. Die Verbrennungseigenschaften von mechanisch oder mechanisch-biologisch vorbehandeltem Restmuell weichen allerdings von denen von unbehandeltem Restmuell ab. In dieser zweiten Projektphase des Forschungsvorhabens wurde eine Untersuchung bezueglich der thermischen Behandelbarkeit von mechanisch und auch biologisch vorbehandeltem Muell durchgefuehrt. Die Ergebnisse der Messkampagnen bilden zusammen mit den Ergebnissen der ersten Projektphase, in der ausschliesslich mechanisch vorbehandeltes Material durchgesetzt wurde, eine umfassende Darstellung ueber Moeglichkeiten und veraenderte Anlagenverhalten bei der thermischen Behandlung von Teilfraktionen aus der biologisch-mechanisch Vorbehandlung. (orig.)

  9. Current research in Radiation Biology and Biochemistry Division

    International Nuclear Information System (INIS)

    Tarachand, U.; Singh, B.B.

    1995-01-01

    The Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay has been engaged in research in the frontier areas of (i) radiation biology related to tumour therapy and injury caused by free radicals; (ii) molecular basis of diseases of physiological origin; (iii) molecular aspects of chemical carcinogenesis and (iv) structure of genome and genome related functions. The gist of research and development activities carried out in the Division during the last two years are documented

  10. Current research in Radiation Biology and Biochemistry Division

    Energy Technology Data Exchange (ETDEWEB)

    Tarachand, U; Singh, B B [eds.; Bhabha Atomic Research Centre, Bombay (India). Radiation Biology and Biochemistry Div.

    1996-12-31

    The Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay has been engaged in research in the frontier areas of (i) radiation biology related to tumour therapy and injury caused by free radicals; (ii) molecular basis of diseases of physiological origin; (iii) molecular aspects of chemical carcinogenesis and (iv) structure of genome and genome related functions. The gist of research and development activities carried out in the Division during the last two years are documented.

  11. NGA-West2 Research Project

    Science.gov (United States)

    Bozorgnia, Yousef; Abrahamson, Norman A.; Al Atik, Linda; Ancheta, Timothy D.; Atkinson, Gail M.; Baker, Jack W.; Baltay, Annemarie S.; Boore, David M.; Campbell, Kenneth W.; Chiou, Brian S.J.; Darragh, Robert B.; Day, Steve; Donahue, Jennifer; Graves, Robert W.; Gregor, Nick; Hanks, Thomas C.; Idriss, I. M.; Kamai, Ronnie; Kishida, Tadahiro; Kottke, Albert; Mahin, Stephen A.; Rezaeian, Sanaz; Rowshandel, Badie; Seyhan, Emel; Shahi, Shrey; Shantz, Tom; Silva, Walter; Spudich, Paul A.; Stewart, Jonathan P.; Watson-Lamprey, Jennie; Wooddell, Kathryn; Youngs, Robert

    2014-01-01

    The NGA-West2 project is a large multidisciplinary, multi-year research program on the Next Generation Attenuation (NGA) models for shallow crustal earthquakes in active tectonic regions. The research project has been coordinated by the Pacific Earthquake Engineering Research Center (PEER), with extensive technical interactions among many individuals and organizations. NGA-West2 addresses several key issues in ground-motion seismic hazard, including updating the NGA database for a magnitude range of 3.0–7.9; updating NGA ground-motion prediction equations (GMPEs) for the “average” horizontal component; scaling response spectra for damping values other than 5%; quantifying the effects of directivity and directionality for horizontal ground motion; resolving discrepancies between the NGA and the National Earthquake Hazards Reduction Program (NEHRP) site amplification factors; analysis of epistemic uncertainty for NGA GMPEs; and developing GMPEs for vertical ground motion. This paper presents an overview of the NGA-West2 research program and its subprojects.

  12. Abstract and research accomplishments of University Coal Research Projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Principal Investigators of the grants supported by the University Coal Research Program were requested to submit abstracts and highlight accomplishments of their respective projects in time for distribution at a conference on June 13--14, 1995 at Tennessee State University in Nashville, Tennessee. This book is a compilation of the material received in response to that request. For convenience, the 70 grants reported in this book are stored into eight technical areas, Coal Science, Coal Surface Science, Reaction Chemistry, Advanced Process Concepts, Engineering Fundamentals and Thermodynamics, Environmental Science, high Temperature Phenomena, and Special topics. Indexes are provided for locating projects by subject, principal investigators, and contracting organizations. Each extended abstract describes project objectives, work accomplished, significance to the Fossil Energy Program, and plans for the next year.

  13. International Interdisciplinary Research Institute Project in Senegal

    Science.gov (United States)

    Gueye, Paul

    2010-02-01

    The project of an interdisciplinary research institute in Senegal was initiated in 1993 in Senegal (West Africa) and became a template for a similar project in the US in 1999. Since then, numerous meetings and presentations have been held at various national and international institutions, workshops and conferences. The current development of this partnership includes drafts for a full design of all systems at each facility, as well as the physics, applied health and educational programs to be implemented. The Senegal facility was conceived for scientific capacity building and equally to act as a focal point aimed at using the local scientific expertise. An anticipated outcome would be a contribution to the reduction of an ever-growing brain drain process suffered by the country, and the African continent in general. The development of the project led also to a strong African orientation of the facility: built for international collaboration, it is to be a pan-African endeavor and to serve primarily African countries. The facility received a presidential approval in a 2003 meeting and will develop an interdisciplinary program centered on a strong materials science research which will also allow for the establishment of an advanced analytical (physical chemistry) laboratory. A central part of the facility will be linked to state-of-the art accelerator mass spectrometry, cyclotron and low energy electromagnetic accelerator systems. )

  14. Annual review of research projects 1987

    International Nuclear Information System (INIS)

    Keam, D.W.

    1989-04-01

    The Australian Radiation Laboratory is a national laboratory whose function is to assist the users of radiation, and those who regulate its use, to ensure that wherever radiation is encountered, it is managed in the safest possible way. In performing this function the Laboratory conducts a varied program of applied research in areas which have implications for occupational or public health. This progress report provides a brief outline of current Laboratory research and development projects and their present status. The material is grouped into the following research fields: uranium, radon and its daughters; environmental radiation monitoring; radiopharmaceuticals and nuclear medicine; X-ray and clinical dosimetry; radionuclide metrology; non-ionising electromagnetic radiations; measurement standards in radiation dosimetry; and radiation effects in solids and gases. Refs., figs., tabs

  15. Synthesis on biological soil crust research

    Science.gov (United States)

    Weber, Bettina; Belnap, Jayne; Buedel, Burkhard

    2016-01-01

    In this closing chapter, we summarize the advances in biocrust research made during the last 1.5 decades. In the first part of the chapter, we discuss how in some research fields, such as the microbial diversity of fungi, bacteria, and microfauna; the interaction between biocrusts and vascular plants; and in the rehabilitation of biocrusts; particularly large achievements have been made. In other fields, previously established knowledge of overall patterns has been corroborated and refined by additional studies, e.g., in the fields of soil stabilization and disturbance effects. In the second part of the chapter, we outline the research gaps and challenges foreseen by us. We identify multiple knowledge gaps, including many understudied geographic regions, the largely missing link between genetic and morphological species identification data, and the answers to some mechanistic questions, such as the overall role of biocrusts in hydrology and nutrient cycles. With some ideas on promising new research questions and approaches we close this chapter and the overall book.

  16. Abstracts and research accomplishments of university coal research projects

    International Nuclear Information System (INIS)

    1991-06-01

    The Principal Investigators of the grants supported by the University Coal Research Program were requested to submit abstracts and highlight accomplishments of their projects in time for distribution at a grantees conference. This book is a compilation of the material received in response to the request. Abstracts discuss the following area: coal science, coal surface science, reaction chemistry, advanced process concepts, engineering fundamentals and thermodynamics, environmental science

  17. Abstracts and research accomplishments of university coal research projects

    Energy Technology Data Exchange (ETDEWEB)

    1991-06-01

    The Principal Investigators of the grants supported by the University Coal Research Program were requested to submit abstracts and highlight accomplishments of their projects in time for distribution at a grantees conference. This book is a compilation of the material received in response to the request. Abstracts discuss the following area: coal science, coal surface science, reaction chemistry, advanced process concepts, engineering fundamentals and thermodynamics, environmental science.

  18. Researchers' experience with project management in health and medical research: Results from a post-project review

    Science.gov (United States)

    2011-01-01

    Background Project management is widely used to deliver projects on time, within budget and of defined quality. However, there is little published information describing its use in managing health and medical research projects. We used project management in the Alcohol and Pregnancy Project (2006-2008) http://www.ichr.uwa.edu.au/alcoholandpregnancy and in this paper report researchers' opinions on project management and whether it made a difference to the project. Methods A national interdisciplinary group of 20 researchers, one of whom was the project manager, formed the Steering Committee for the project. We used project management to ensure project outputs and outcomes were achieved and all aspects of the project were planned, implemented, monitored and controlled. Sixteen of the researchers were asked to complete a self administered questionnaire for a post-project review. Results The project was delivered according to the project protocol within the allocated budget and time frame. Fifteen researchers (93.8%) completed a questionnaire. They reported that project management increased the effectiveness of the project, communication, teamwork, and application of the interdisciplinary group of researchers' expertise. They would recommend this type of project management for future projects. Conclusions Our post-project review showed that researchers comprehensively endorsed project management in the Alcohol and Pregnancy Project and agreed that project management had contributed substantially to the research. In future, we will project manage new projects and conduct post-project reviews. The results will be used to encourage continuous learning and continuous improvement of project management, and provide greater transparency and accountability of health and medical research. The use of project management can benefit both management and scientific outcomes of health and medical research projects. PMID:21635721

  19. NCI RNA Biology 2017 symposium recap | Center for Cancer Research

    Science.gov (United States)

    The recent discovery of new classes of RNAs and the demonstration that alterations in RNA metabolism underlie numerous human cancers have resulted in enormous interest among CCR investigators in RNA biology. In order to share the latest research in this exciting field, the CCR Initiative in RNA Biology held its second international symposium April 23-24, 2017, in Natcher Auditorium. Learn more...

  20. NCI RNA Biology 2017 symposium recap | Center for Cancer Research

    Science.gov (United States)

    The recent discovery of new classes of RNAs and the demonstration that alterations in RNA metabolism underlie numerous human cancers have resulted in enormous interest among CCR investigators in RNA biology. In order to share the latest research in this exciting field, the CCR Initiative in RNA Biology held its second international symposium April 23-24, 2017, in Natcher

  1. Research projects on life management: materials ageing

    International Nuclear Information System (INIS)

    Gomez Briceno, D.

    1997-01-01

    Materials ageing is a time-dependent process, that involves the loss of availability of nuclear plants. Radiation embrittlement, stress corrosion cracking, irradiation assisted stress corrosion cracking, and thermal ageing are the most relevant time-dependent material degradation mechanisms that can be identified in the materials ageing process. The Materials Programme of Nuclear Energy Institute at CIEMAT carries out research projects and metallurgical examinations of failed components to gain some insight into the mechanisms of materials degradation with a direct impact on the life management of nuclear plants. (Author)

  2. Annual review of research projects 1985

    International Nuclear Information System (INIS)

    Keam, D.W.

    1987-04-01

    This progress report provides a brief outline of current Laboratory research and development projects and their present status. The material has been grouped into the following fields: uranium, radon and its daughters; radiation effects in solids and gases; x-rays and clinical dosimetry, measurement standards in radiation dosimetry; radiopharmaceuticals and nuclear medicine; non-ionising electromagnetic radiation; environmental radiochemistry and radiation monitoring. The last category includes residual radioactive contamination at Maralinga, Emu and the Monte Bello Islands from British nuclear weapons tests in Australia, and the public health impact of fall-out from those tests

  3. Stable isotopes: essential tools in biological and medical research

    Energy Technology Data Exchange (ETDEWEB)

    Klein, P. D.; Hachey, D. L.; Kreek, M. J.; Schoeller, D. A.

    1977-01-01

    Recent developments in the use of the stable isotopes, /sup 13/C, /sup 15/N, /sup 17/O, and /sup 18/O, as tracers in research studies in the fields of biology, medicine, pharmacology, and agriculture are briefly reviewed. (CH)

  4. The Earth Microbiome Project and Global Systems Biology

    Energy Technology Data Exchange (ETDEWEB)

    Gilbert, Jack A.; Jansson, Janet K.; Knight, Rob

    2018-04-10

    Recently, we published the first large-scale analysis of data from the Earth Microbiome Project (1, 2), a truly multidisciplinary research program involving more than 500 scientists and 27,751 samples acquired from 43 countries. These samples represent myriad specimen types and span a wide range of biotic and abiotic factors, geographic locations, and physicochemical properties. The database (https://qiita.ucsd.edu/emp/) is still growing, with over 90,000 amplicon datasets, >500 metagenomic runs, and metabolomics datasets from a similar number of samples. Importantly, the techniques, data and analytical tools are all standardized and publicly accessible, providing a framework to support research at a scale of integration that just 7 years ago seemed impossible.

  5. Scintilla European project, the successful research results

    Energy Technology Data Exchange (ETDEWEB)

    Sannie, G.; Kondrasov, V.; Corre, G.; Boudergui, K.; Perot, B.; Carasco, C.; Montemont, G. [Commissariat a l' energie atomique et aux energies alternatives, Saclay, Cadarache, Grenoble (France); Peerani, P.; Carrapico, C.; Tomanin, A.; Rosas, F.; Caviglia, M.; Eklund, G.; Tagziria, H. [European Commission, Joint Research Centre, ITU, Nuclear Security Unit, Ispra (Italy); Friedrich, H.; Chmel, S. [Fraunhofer-Institut fuer Naturwissenschaftlich - Technische Trendanalysen - INT, Euskirchen (Germany); De Vita, R.; Manchini, E.; Pavan, M. [Istituto Nazionale di Fisica Nucleare, Sezione di Genova, Genova (Italy); Grattarola, M.; Botta, E. [Ansaldo Nucleare S.P.A, Genova (Italy); Kovacs, A.; Lakosi, L. [Hungarian Academy of Sciences, Centre for Energy Research, Budapest (Hungary); Baumhauer, C.; Deheuninck, T.; Haddad, E. [ARTTIC, Paris (France); Petrossian, G.; Ferragut, A. [SAPHYMO, Massy (France); Dermody, G.; Crossingham, G. [Symetrica Security Ltd, Southampton (United Kingdom)

    2015-07-01

    The Scintilla FP7 project is ended in December 2014, the fruitful results of 3 years development and tests will be presented. SCINTILLA offers the capacity to finding a reliable alternative to Helium-3 based detection systems since the gas which is predominantly used in nuclear safeguards and security applications has now become very expensive, rare and nearly unavailable. SCINTILLA benchmarks results are based on international standards. Radiation Portal tests were carried out at the Joint Research Centre (JRC) in Ispra (Italy). The scintilla project addresses few mains issues. The first is to develop neutron detectors for Radiation Portal Monitor (RPM) and the second is the need of new wearable integrated solutions for Spectrometric Personal Radiation Monitor (SPRM). The partners which provide technical systems of the scintilla project are INFN-ANSALDO, CEA, SYMETRICA and SAPHYMO. For RPM, the objective is to find reliable alternatives to Helium-3 historical neutron detector and provide technical solutions which cope with tests for reliable mobile and cost effective. For Spectrometric Personal Radiation Monitor (SPRM), SCINTILLA is innovating in technology areas that offer complementary capabilities for detecting and identifying gamma, Two CZT (Cadmium Zinc Telluride) addressing contexts of used by first responder technologies, one is a wearable detector and the second is a gamma camera complemented by advanced image processing technologies. (authors)

  6. National Storage Laboratory: a collaborative research project

    Science.gov (United States)

    Coyne, Robert A.; Hulen, Harry; Watson, Richard W.

    1993-01-01

    The grand challenges of science and industry that are driving computing and communications have created corresponding challenges in information storage and retrieval. An industry-led collaborative project has been organized to investigate technology for storage systems that will be the future repositories of national information assets. Industry participants are IBM Federal Systems Company, Ampex Recording Systems Corporation, General Atomics DISCOS Division, IBM ADSTAR, Maximum Strategy Corporation, Network Systems Corporation, and Zitel Corporation. Industry members of the collaborative project are funding their own participation. Lawrence Livermore National Laboratory through its National Energy Research Supercomputer Center (NERSC) will participate in the project as the operational site and provider of applications. The expected result is the creation of a National Storage Laboratory to serve as a prototype and demonstration facility. It is expected that this prototype will represent a significant advance in the technology for distributed storage systems capable of handling gigabyte-class files at gigabit-per-second data rates. Specifically, the collaboration expects to make significant advances in hardware, software, and systems technology in four areas of need, (1) network-attached high performance storage; (2) multiple, dynamic, distributed storage hierarchies; (3) layered access to storage system services; and (4) storage system management.

  7. Restoration projects for decontamination of facilities from chemical, biological and radiological contamination after terrorist actions

    Energy Technology Data Exchange (ETDEWEB)

    Fingas, M.; Volchek, K.; Lumley, T.; Thouin, G.; Harrison, S.; Kuang, W. [Environment Canada, Ottawa, ON (Canada). Emergencies Science and Technology Division, Environmental Technology Centre, Science and Technology Branch; Payette, P.; Laframboise, D.; Best, M. [Public Health Agency of Canada, Ottawa, ON (Canada); Krishnan, J.; Wagener, S.; Bernard, K.; Majcher, M. [Public Health Agency of Canada, Winnipeg, MB (Canada); Cousins, T.; Jones, T. [Defence Research and Development Canada, Ottawa, ON (Canada); Velicogna, D.; Hornof, M.; Punt, M. [SAIC Canada, Ottawa, ON (Canada)

    2006-07-01

    This paper reviewed studies that identified better decontamination methods for chemical, biological and radiological/nuclear (CBRN) attacks. In particular, it reviewed aspects of 3 projects in which procedures were tested and validated for site restoration. Cleanup targets or standards for decontaminating buildings and materials after a CBRN attack were also developed. The projects were based on physicochemical and toxicological knowledge of potential terrorist agents and selected surface matrices. The projects also involved modeling and assessing environmental and health risks. The first multi-agent project involved gathering information on known procedures for restoration of areas including interiors and exteriors of buildings, contents, parking lots, lawn, and vehicles. Air inside the building was included. The efficacy of some of the proposed concepts was tested. Results included the determination of appropriate surrogates for anthrax and tests of liquid and gaseous biocides on the surrogates. The development of new contamination procedures using peroxyacetic acid were also discussed. The second project involved decontamination tests on CBRN using specially-constructed buildings at the Counter-terrorism Technology Centre at Defence Research and Development Canada in Suffield. The buildings will be contaminated with chemical and biological agents and with short-lived radionuclides. They will be decontaminated using the best-performing technologies known. Information collected will include fate of the contaminant and decontamination products, effectiveness of the restoration methods, cost and duration of cleanup and logistical problems. The third project is aimed at developing cleanup standards for decontaminating buildings and construction materials after a chemical or biological attack. It will create as many as 12 algorithms for the development of 50 standards which will help cleanup personnel and first-responders to gauge whether proposed methods can achieve

  8. Social justice and research using human biological material: A ...

    African Journals Online (AJOL)

    Social justice and research using human biological material: A response to Mahomed, Nöthling-Slabbert and Pepper. ... South African Medical Journal ... In a recent article, Mahomed, Nöthling-Slabbert and Pepper proposed that research participants should be entitled to share in the profits emanating from such research ...

  9. Biological Research in Canisters (BRIC) - Light Emitting Diode (LED)

    Science.gov (United States)

    Levine, Howard G.; Caron, Allison

    2016-01-01

    The Biological Research in Canisters - LED (BRIC-LED) is a biological research system that is being designed to complement the capabilities of the existing BRIC-Petri Dish Fixation Unit (PDFU) for the Space Life and Physical Sciences (SLPS) Program. A diverse range of organisms can be supported, including plant seedlings, callus cultures, Caenorhabditis elegans, microbes, and others. In the event of a launch scrub, the entire assembly can be replaced with an identical back-up unit containing freshly loaded specimens.

  10. The Systems Biology Research Tool: evolvable open-source software

    Directory of Open Access Journals (Sweden)

    Wright Jeremiah

    2008-06-01

    Full Text Available Abstract Background Research in the field of systems biology requires software for a variety of purposes. Software must be used to store, retrieve, analyze, and sometimes even to collect the data obtained from system-level (often high-throughput experiments. Software must also be used to implement mathematical models and algorithms required for simulation and theoretical predictions on the system-level. Results We introduce a free, easy-to-use, open-source, integrated software platform called the Systems Biology Research Tool (SBRT to facilitate the computational aspects of systems biology. The SBRT currently performs 35 methods for analyzing stoichiometric networks and 16 methods from fields such as graph theory, geometry, algebra, and combinatorics. New computational techniques can be added to the SBRT via process plug-ins, providing a high degree of evolvability and a unifying framework for software development in systems biology. Conclusion The Systems Biology Research Tool represents a technological advance for systems biology. This software can be used to make sophisticated computational techniques accessible to everyone (including those with no programming ability, to facilitate cooperation among researchers, and to expedite progress in the field of systems biology.

  11. The Advanced Interdisciplinary Research Laboratory: A Student Team Approach to the Fourth-Year Research Thesis Project Experience

    Science.gov (United States)

    Piunno, Paul A. E.; Boyd, Cleo; Barzda, Virginijus; Gradinaru, Claudiu C.; Krull, Ulrich J.; Stefanovic, Sasa; Stewart, Bryan

    2014-01-01

    The advanced interdisciplinary research laboratory (AIRLab) represents a novel, effective, and motivational course designed from the interdisciplinary research interests of chemistry, physics, biology, and education development faculty members as an alternative to the independent thesis project experience. Student teams are assembled to work…

  12. On-going research projects at Ankara Nuclear Research Center in Agriculture and Animal Science

    International Nuclear Information System (INIS)

    Tukenmez, I.

    2004-01-01

    Full text: The research and development activities of Ankara Nuclear Research Center in Agriculture and Animal Science(ANRCAA) are concentrated on the contribution of atomic energy to peace by the use of nuclear and related techniques in food, agriculture and animal science. Nuclear techniques are used in the above fields in two ways: in vitro or in vivo radio tracing the substances and processes of biological importance, and irradiation of biological materials for preservation and quality modification. Research projects are carried out by interdisciplinary studies with well equipped laboratories at the Center. The projects in progress conducted by the Center comprises nuclear-aided researches in soil fertility, plant nutrition, plant protection, improvement of field crops, improvement of horticultural plants and forest trees by mutation breeding, in vitro culture technique with mutagen treatments, use of phosphogypsum in soil amelioration, sterilization of medical supplies, wastewater treatment, animal nutrition, animal health and productivity and accreditation. The on-going projects with the above subjects will be summarized for possible collaborations

  13. On-going research projects at Ankara Nuclear research center in agriculture and animal science

    International Nuclear Information System (INIS)

    Tukenmez, I.

    2004-01-01

    Full text:The research and development activities of Ankara Nuclear Research Center in Agriculture and Animal Science(ANRCAA) are concentrated on the contribution of atomic energy to peace by the use of nuclear and related techniques in food, agriculture and animal science. Nuclear techniques are used in the above fields in two ways: in vitro or in vivo radio tracing the substances and processes of biological importance, and irradiation of biological materials for preservation and quality modification. Research projects are carried out by interdisciplinary studies with well equipped laboratories at the Center. The projects in progress conducted by the Center comprises nuclear-aided researches in soil fertility, plant nutrition, plant protection, improvement of field crops, improvement of horticultural plants and forest trees by mutation breeding, in vitro culture technique with mutagen treatments, use of phosphogypsum in soil amelioration, sterilization of medical supplies, wastewater treatment, animal nutrition, animal health and productivity and accreditation. The on-going projects with the above subjects will be summarized for possible collaborations

  14. Fast Charging Electric Vehicle Research & Development Project

    Energy Technology Data Exchange (ETDEWEB)

    Heny, Michael

    2014-03-31

    The research and development project supported the engineering, design and implementation of on-road Electric Vehicle (“EV”) charging technologies. It included development of potential solutions for DC fast chargers (“DCFC”) capable of converting high voltage AC power to the DC power required by EVs. Additional development evaluated solutions related to the packaging of power electronic components and enclosure design, as well as for the design and evaluation of EV charging stations. Research compared different charging technologies to identify optimum applications in a municipal fleet. This project collected EV usage data and generated a report demonstrating that EVs, when supported by adequate charging infrastructure, are capable of replacing traditional internal combustion vehicles in many municipal applications. The project’s period of performance has demonstrated various methods of incorporating EVs into a municipal environment, and has identified three general categories for EV applications: Short Commute: Defined as EVs performing in limited duration, routine commutes. - Long Commute: Defined as tasks that require EVs to operate in longer daily mileage patterns. - Critical Needs: Defined as the need for EVs to be ready at every moment for indefinite periods. Together, the City of Charlottesville, VA (the “City”) and Aker Wade Power Technologies, LLC (“Aker Wade”) concluded that the EV has a viable position in many municipal fleets but with limited recommendation for use in Critical Needs applications such as Police fleets. The report also documented that, compared to internal combustion vehicles, BEVs have lower vehicle-related greenhouse gas (“GHG”) emissions and contribute to a reduction of air pollution in urban areas. The enhanced integration of EVs in a municipal fleet can result in reduced demand for imported oil and reduced municipal operating costs. The conclusions indicated in the project’s Engineering Report (see Attachment

  15. Data management strategies for multinational large-scale systems biology projects.

    Science.gov (United States)

    Wruck, Wasco; Peuker, Martin; Regenbrecht, Christian R A

    2014-01-01

    Good accessibility of publicly funded research data is essential to secure an open scientific system and eventually becomes mandatory [Wellcome Trust will Penalise Scientists Who Don't Embrace Open Access. The Guardian 2012]. By the use of high-throughput methods in many research areas from physics to systems biology, large data collections are increasingly important as raw material for research. Here, we present strategies worked out by international and national institutions targeting open access to publicly funded research data via incentives or obligations to share data. Funding organizations such as the British Wellcome Trust therefore have developed data sharing policies and request commitment to data management and sharing in grant applications. Increased citation rates are a profound argument for sharing publication data. Pre-publication sharing might be rewarded by a data citation credit system via digital object identifiers (DOIs) which have initially been in use for data objects. Besides policies and incentives, good practice in data management is indispensable. However, appropriate systems for data management of large-scale projects for example in systems biology are hard to find. Here, we give an overview of a selection of open-source data management systems proved to be employed successfully in large-scale projects.

  16. Personal recollections of radiation biology research at Hanford

    International Nuclear Information System (INIS)

    Thompson, R.C.

    1995-01-01

    This paper traces the evolution of the Hanford biology programme over a period of nearly five decades. The programme began in the 1940s with a focus on understanding the potential health effects of radionuclides such as 131 I associated with fallout from the atomic bomb. These studies were extended in the 1950s to experiments on the toxicity and metabolism of plutonium and fission products such as 90 Sr and 137 Cs. In the 1960s, a major long term project was initiated on the inhalation toxicology and carcinogenic effects of plutonium oxide and plutonium nitrate in dogs and rodents. The project remained a major effort within the overall Hanford biology programme throughout the 1970s and 1980s, during which time a broad range of new projects on energy-related pollutants, radon health effects, and basic radiation biology were initiated. Despite the many evolutionary changes that have occurred in the Hanford biology programme, the fundamental mission of understanding the effects of radiation on human health has endured for nearly five decades. (author)

  17. National inventory of selected biological monitoring programs. Summary report of current or recently completed projects, 1976

    Energy Technology Data Exchange (ETDEWEB)

    Kemp, H. T.

    1976-10-01

    The Inventory has resulted in establishment of a series of data bases containing biological monitoring information of varying types, namely, directory of investigators, record of projects received from mail questionnaire, detailed description of selected biomonitoring projects, and bibliographic citations supporting the projects received. This report contains detailed descriptions of selected biomonitoring projects organized on a state-by-state basis and with appropriate indices.

  18. Astronomy Legacy Project - Pisgah Astronomical Research Institute

    Science.gov (United States)

    Barker, Thurburn; Castelaz, Michael W.; Rottler, Lee; Cline, J. Donald

    2016-01-01

    Pisgah Astronomical Research Institute (PARI) is a not-for-profit public foundation in North Carolina dedicated to providing hands-on educational and research opportunities for a broad cross-section of users in science, technology, engineering and math (STEM) disciplines. In November 2007 a Workshop on a National Plan for Preserving Astronomical Photographic Data (2009ASPC,410,33O, Osborn, W. & Robbins, L) was held at PARI. The result was the establishment of the Astronomical Photographic Data Archive (APDA) at PARI. In late 2013 PARI began ALP (Astronomy Legacy Project). ALP's purpose is to digitize an extensive set of twentieth century photographic astronomical data housed in APDA. Because of the wide range of types of plates, plate dimensions and emulsions found among the 40+ collections, plate digitization will require a versatile set of scanners and digitizing instruments. Internet crowdfunding was used to assist in the purchase of additional digitization equipment that were described at AstroPlate2014 Plate Preservation Workshop (www.astroplate.cz) held in Prague, CZ, March, 2014. Equipment purchased included an Epson Expression 11000XL scanner and two Nikon D800E cameras. These digital instruments will compliment a STScI GAMMA scanner now located in APDA. GAMMA will be adapted to use an electroluminescence light source and a digital camera with a telecentric lens to achieve high-speed high-resolution scanning. The 1μm precision XY stage of GAMMA will allow very precise positioning of the plate stage. Multiple overlapping CCD images of small sections of each plate, tiles, will be combined using a photo-mosaic process similar to one used in Harvard's DASCH project. Implementation of a software pipeline for the creation of a SQL database containing plate images and metadata will be based upon APPLAUSE as described by Tuvikene at AstroPlate2014 (www.astroplate.cz/programs/).

  19. A practical workflow for making anatomical atlases for biological research.

    Science.gov (United States)

    Wan, Yong; Lewis, A Kelsey; Colasanto, Mary; van Langeveld, Mark; Kardon, Gabrielle; Hansen, Charles

    2012-01-01

    The anatomical atlas has been at the intersection of science and art for centuries. These atlases are essential to biological research, but high-quality atlases are often scarce. Recent advances in imaging technology have made high-quality 3D atlases possible. However, until now there has been a lack of practical workflows using standard tools to generate atlases from images of biological samples. With certain adaptations, CG artists' workflow and tools, traditionally used in the film industry, are practical for building high-quality biological atlases. Researchers have developed a workflow for generating a 3D anatomical atlas using accessible artists' tools. They used this workflow to build a mouse limb atlas for studying the musculoskeletal system's development. This research aims to raise the awareness of using artists' tools in scientific research and promote interdisciplinary collaborations between artists and scientists. This video (http://youtu.be/g61C-nia9ms) demonstrates a workflow for creating an anatomical atlas.

  20. Quarterly report of Biological and Medical Research Division, April 1955

    Energy Technology Data Exchange (ETDEWEB)

    Brues, A.M.

    1955-04-01

    This report is a compilation of 48 investigator prepared summaries of recent progress in individual research programs of the Biology and Medical Division of the Argonne National Laboratory for the quarterly period ending April,1955. Individual reports are about 3-6 pages in length and often contain research data.

  1. Consortium biology in immunology: the perspective from the Immunological Genome Project.

    Science.gov (United States)

    Benoist, Christophe; Lanier, Lewis; Merad, Miriam; Mathis, Diane

    2012-10-01

    Although the field has a long collaborative tradition, immunology has made less use than genetics of 'consortium biology', wherein groups of investigators together tackle large integrated questions or problems. However, immunology is naturally suited to large-scale integrative and systems-level approaches, owing to the multicellular and adaptive nature of the cells it encompasses. Here, we discuss the value and drawbacks of this organization of research, in the context of the long-running 'big science' debate, and consider the opportunities that may exist for the immunology community. We position this analysis in light of our own experience, both positive and negative, as participants of the Immunological Genome Project.

  2. Bringing the physical sciences into your cell biology research.

    Science.gov (United States)

    Robinson, Douglas N; Iglesias, Pablo A

    2012-11-01

    Historically, much of biology was studied by physicists and mathematicians. With the advent of modern molecular biology, a wave of researchers became trained in a new scientific discipline filled with the language of genes, mutants, and the central dogma. These new molecular approaches have provided volumes of information on biomolecules and molecular pathways from the cellular to the organismal level. The challenge now is to determine how this seemingly endless list of components works together to promote the healthy function of complex living systems. This effort requires an interdisciplinary approach by investigators from both the biological and the physical sciences.

  3. Campus Eco Tours: An Integrative & Interactive Field Project for Undergraduate Biology Students

    Science.gov (United States)

    Boes, Katie E.

    2013-01-01

    Outdoor areas within or near college campuses offer an opportunity for biology students to observe the natural world and apply concepts from class. Here, I describe an engaging and integrative project where undergraduate non-major biology students work in teams to develop and present professional "eco tours." This project takes place over multiple…

  4. Tools for Monitoring Social Media: A Marketing Research Project

    Science.gov (United States)

    Veeck, Ann; Hoger, Beth

    2014-01-01

    Knowledge of how to effectively monitor social media is an increasingly valued marketing research skill. This study tests an approach for adding social media content to an undergraduate marketing research class team project. The revised project maintains the expected objectives and parameters of a traditional research project, while integrating…

  5. Biological and Physical Space Research Laboratory 2002 Science Review

    Science.gov (United States)

    Curreri, P. A. (Editor); Robinson, M. B. (Editor); Murphy, K. L. (Editor)

    2003-01-01

    With the International Space Station Program approaching core complete, our NASA Headquarters sponsor, the new Code U Enterprise, Biological and Physical Research, is shifting its research emphasis from purely fundamental microgravity and biological sciences to strategic research aimed at enabling human missions beyond Earth orbit. Although we anticipate supporting microgravity research on the ISS for some time to come, our laboratory has been vigorously engaged in developing these new strategic research areas.This Technical Memorandum documents the internal science research at our laboratory as presented in a review to Dr. Ann Whitaker, MSFC Science Director, in July 2002. These presentations have been revised and updated as appropriate for this report. It provides a snapshot of the internal science capability of our laboratory as an aid to other NASA organizations and the external scientific community.

  6. NASA Space Biology Plant Research for 2010-2020

    Science.gov (United States)

    Levine, H. G.; Tomko, D. L.; Porterfield, D. M.

    2012-01-01

    The U.S. National Research Council (NRC) recently published "Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era" (http://www.nap.edu/catalog.php?record id=13048), and NASA completed a Space Biology Science Plan to develop a strategy for implementing its recommendations ( http://www.nasa.gov/exploration/library/esmd documents.html). The most important recommendations of the NRC report on plant biology in space were that NASA should: (1) investigate the roles of microbial-plant systems in long-term bioregenerative life support systems, and (2) establish a robust spaceflight program of research analyzing plant growth and physiological responses to the multiple stimuli encountered in spaceflight environments. These efforts should take advantage of recently emerged analytical technologies (genomics, transcriptomics, proteomics, metabolomics) and apply modern cellular and molecular approaches in the development of a vigorous flight-based and ground-based research program. This talk will describe NASA's strategy and plans for implementing these NRC Plant Space Biology recommendations. New research capabilities for Plant Biology, optimized by providing state-of-the-art automated technology and analytical techniques to maximize scientific return, will be described. Flight experiments will use the most appropriate platform to achieve science results (e.g., ISS, free flyers, sub-orbital flights) and NASA will work closely with its international partners and other U.S. agencies to achieve its objectives. One of NASA's highest priorities in Space Biology is the development research capabilities for use on the International Space Station and other flight platforms for studying multiple generations of large plants. NASA will issue recurring NASA Research Announcements (NRAs) that include a rapid turn-around model to more fully engage the biology community in designing experiments to respond to the NRC recommendations. In doing so, NASA

  7. What do medical students understand by research and research skills? Identifying research opportunities within undergraduate projects.

    Science.gov (United States)

    Murdoch-Eaton, Deborah; Drewery, Sarah; Elton, Sarah; Emmerson, Catherine; Marshall, Michelle; Smith, John A; Stark, Patsy; Whittle, Sue

    2010-01-01

    Undergraduate research exposure leads to increased recruitment into academic medicine, enhanced employability and improved postgraduate research productivity. Uptake of undergraduate research opportunities is reported to be disappointing, and little is known about how students perceive research. To investigate opportunities for undergraduate participation in research, recognition of such opportunities, and associated skills development. A mixed method approach, incorporating student focus and study groups, and documentary analysis at five UK medical schools. Undergraduates recognised the benefits of acquiring research skills, but identified practical difficulties and disadvantages of participating. Analysis of 905 projects in four main research skill areas - (1) research methods; (2) information gathering; (3) critical analysis and review; (4) data processing - indicated 52% of projects provided opportunities for students to develop one or more skills, only 13% offered development in all areas. In 17%, project descriptions provided insufficient information to determine opportunities. Supplied with information from a representative sample of projects (n = 80), there was little consensus in identifying skills among students or between students and researchers. Consensus improved dramatically following guidance on how to identify skills. Undergraduates recognise the benefits of research experience but need a realistic understanding of the research process. Opportunities for research skill development may not be obvious. Undergraduates require training to recognise the skills required for research and enhanced transparency in potential project outcomes.

  8. Research into condensed matter using large-scale apparatus. Physics, chemistry, biology. Progress report 1992-1995. Summarizing reports

    International Nuclear Information System (INIS)

    1996-01-01

    Activities for research into condensed matter have been supported by the German BMBF with approx. 102 million Deutschmarks in the years 1992 through 1995. These financial means have been distributed among 314 research projects in the fields of physics, chemistry, biology, materials science, and other fields, which all rely on the intensive utilization of photon and particle beams generated in large-scale apparatus of institutions for basic research. The volume in hand first gives information of a general kind and statistical data on the distribution of financial means, for a number of priority research projects. The project reports are summarizing reports on the progress achieved in the various projects. (CB) [de

  9. The value of closed-circuit rebreathers for biological research

    Science.gov (United States)

    Pyle, Richrad L.; Lobel, Phillip S.; Tomoleoni, Joseph

    2016-01-01

    Closed-circuit rebreathers have been used for underwater biological research since the late 1960s, but have only started to gain broader application within scientific diving organizations within the past two decades. Rebreathers offer certain specific advantages for such research, especially for research involving behavior and surveys that depend on unobtrusive observers or for a stealthy approach to wildlife for capture and tagging, research that benefits from extended durations underwater, and operations requiring access to relatively deep (>50 m) environments (especially in remote locations). Although many institutions have been slow to adopt rebreather technology within their diving programs, recent developments in rebreather technology that improve safety, standardize training requirements, and reduce costs of equipment and maintenance, will likely result in a trend of increasing utilization of rebreathers for underwater biological research.

  10. Bibliographical review on the teaching of Biology and research

    Directory of Open Access Journals (Sweden)

    Mª Luz Rodríguez Palmero

    2000-09-01

    Full Text Available This review complements another one done by the same author, in 1997, regarding the role of comprehending the concept of cell in the learning of Biology. In addition, some general papers on science education that provide a better understanding of research approaches used in the investigation of this topic have been included. The reviewed papers have been organized into categories according to the object of study, the relevance assigned to the cell concept, and the framework of analysis. The review shows that the concept of cell is very important in the biological conceptualization, however, it also shows the need of additional research on this matter, from theoretical frameworks that pay more attention to the psychological level, in order to provide some guidance to improve the teaching and learning processes of the biological content that presupose the comprehension of living beings.

  11. Project Work in Social Biology at GCE Advanced Level

    Science.gov (United States)

    Gadd, P.; Smith, S. Tyrell

    1977-01-01

    The system by which projects are submitted, modified, and approved is outlined and an indication is given of the standards and quantity of work expected. Criteria on which assessment is based are explained, the range of individual studies is summarized, and cases for and against project work are given. (Author/AJ)

  12. Sixth-Form Projects in Biology: A Case History.

    Science.gov (United States)

    Robinson, P. M.; Parker, R. E.

    1981-01-01

    Some of the problems encountered in devising sixth-form projects are discussed and a detailed account given of one project in which a study was made of the effect of onion bulb volatiles on the germination of lettuce seed. (Author)

  13. Biomedical Research Experiences for Biology Majors at a Small College

    Science.gov (United States)

    Stover, Shawn K.; Mabry, Michelle L.

    2010-01-01

    A program-level assessment of the biology curriculum at a small liberal arts college validates a previous study demonstrating success in achieving learning outcomes related to content knowledge and communication skills. Furthermore, research opportunities have been provided to complement pedagogical strategies and give students a more complete…

  14. Biologically Enhanced Carbon Sequestration: Research Needs and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Oldenburg, Curtis; Oldenburg, Curtis M.; Torn, Margaret S.

    2008-03-21

    Fossil fuel combustion, deforestation, and biomass burning are the dominant contributors to increasing atmospheric carbon dioxide (CO{sub 2}) concentrations and global warming. Many approaches to mitigating CO{sub 2} emissions are being pursued, and among the most promising are terrestrial and geologic carbon sequestration. Recent advances in ecology and microbial biology offer promising new possibilities for enhancing terrestrial and geologic carbon sequestration. A workshop was held October 29, 2007, at Lawrence Berkeley National Laboratory (LBNL) on Biologically Enhanced Carbon Sequestration (BECS). The workshop participants (approximately 30 scientists from California, Illinois, Oregon, Montana, and New Mexico) developed a prioritized list of research needed to make progress in the development of biological enhancements to improve terrestrial and geologic carbon sequestration. The workshop participants also identified a number of areas of supporting science that are critical to making progress in the fundamental research areas. The purpose of this position paper is to summarize and elaborate upon the findings of the workshop. The paper considers terrestrial and geologic carbon sequestration separately. First, we present a summary in outline form of the research roadmaps for terrestrial and geologic BECS. This outline is elaborated upon in the narrative sections that follow. The narrative sections start with the focused research priorities in each area followed by critical supporting science for biological enhancements as prioritized during the workshop. Finally, Table 1 summarizes the potential significance or 'materiality' of advances in these areas for reducing net greenhouse gas emissions.

  15. Biological field stations: research legacies and sites for serendipity

    Science.gov (United States)

    William K. Michener; Keith L. Bildstein; Arthur McKee; Robert R. Parmenter; William W. Hargrove; Deedra McClearn; Mark Stromberg

    2009-01-01

    Biological field stations are distributed throughout North America, capturing much of the ecological variability present at the continental scale and encompassing many unique habitats. In addition to their role in supporting research and education, field stations offer legacies of data, specimens, and accumulated knowledge. Such legacies often provide the only...

  16. Researchers study decontamination of chemical, biological warfare agents

    OpenAIRE

    Trulove, Susan

    2007-01-01

    The U.S. Army Research Office has awarded Virginia Tech a $680,000 grant over two years to build an instrument that can be used to study the chemistry of gases that will decompose both chemical and biological warfare agents on surfaces.

  17. Teaching Cell Biology to Dental Students with a Project-Based Learning Approach.

    Science.gov (United States)

    Costa-Silva, Daniela; Côrtes, Juliana A; Bachinski, Rober F; Spiegel, Carolina N; Alves, Gutemberg G

    2018-03-01

    Although the discipline of cell biology (CB) is part of the curricula of predoctoral dental schools, students often fail to recognize its practical relevance. The aim of this study was to assess the effectiveness of a practical-theoretical project-based course in closing the gaps among CB, scientific research, and dentistry for dental students. A project-based learning course was developed with nine sequential lessons to evaluate 108 undergraduate dental students enrolled in CB classes of a Brazilian school of dentistry during 2013-16. To highlight the relevance of in vitro studies in the preclinical evaluation of dental materials at the cellular level, the students were challenged to complete the process of drafting a protocol and performing a cytocompatibility assay for a bone substitute used in dentistry. Class activities included small group discussions, scientific database search and article presentations, protocol development, lab experimentation, and writing of a final scientific report. A control group of 31 students attended only one laboratory class on the same theme, and the final reports were compared between the two groups. The results showed that the project-based learning students had superior outcomes in acknowledging the relevance of in vitro methods during biocompatibility testing. Moreover, they produced scientifically sound reports with more content on methodological issues, the relationship with dentistry, and the scientific literature than the control group (p<0.05). The project-based learning students also recognized a higher relevance of scientific research and CB to dental practice. These results suggest that a project-based approach can help contextualize scientific research in dental curricula.

  18. 30 CFR 402.10 - Research-project applications.

    Science.gov (United States)

    2010-07-01

    ... project title, project objectives, background information, research tasks, methodology to conduct the... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Research-project applications. 402.10 Section... PROGRAM AND THE WATER-RESOURCES TECHNOLOGY DEVELOPMENT PROGRAM Application, Evaluation, and Management...

  19. ENSAR, a Nuclear Science Project for European Research Area

    NARCIS (Netherlands)

    Turzó, Ketel; Lewitowicz, Marek; Harakeh, Muhsin N.

    2015-01-01

    During the period from September 2010 to December 2014, the European project European Nuclear Science and Applications Research (ENSAR) coordinated research activities of the Nuclear Physics community performing research in three major subfields: Nuclear Structure, Nuclear Astrophysics, and Nuclear

  20. Methodology for evaluation of railroad technology research projects

    Science.gov (United States)

    1981-04-01

    This Project memorandum presents a methodology for evaluating railroad research projects. The methodology includes consideration of industry and societal benefits, with special attention given to technical risks, implementation considerations, and po...

  1. Research on stored biological samples: views of African American and White American cancer patients.

    Science.gov (United States)

    Pentz, Rebecca D; Billot, Laurent; Wendler, David

    2006-04-01

    Proposals on consent for research with biological samples should be informed by empirical studies of individuals' views. Studies to date queried mostly white research subjects. The aim of this study was to compare the views of two groups of patients: cancer patients at a university clinic (Winship Cancer Institute at Emory Healthcare) and cancer patients at an inner city county hospital (Grady) who were given the option of tissue banking. Overall, 315/452 (70%) patients completed the survey. The Grady cohort was 86% African American; the Winship cohort was 82% White. The vast majority (95%) of individuals in both cohorts agreed to provide a biological sample for future research. Both cohorts were willing for their samples to be used to study cancer and other diseases, including Alzheimer disease. Few participants preferred to control the disease to be studied (10%) or wished to be contacted again for consent for each future research project (11%). In our sample, almost all clinical patients, regardless of site of care, ethnicity or socioeconomic status, were willing to provide a biological sample for research purposes and allow investigators to determine the research to be done without contacting the patients again. These findings support the recommendation to offer individuals a simplified consent with a one-time binary choice whether to provide biological samples for future research. Copyright 2006 Wiley-Liss, Inc.

  2. From Never Born Proteins to Minimal Living Cells: two projects in synthetic biology.

    Science.gov (United States)

    Luisi, Pier Luigi; Chiarabelli, Cristiano; Stano, Pasquale

    2006-12-01

    The Never Born Proteins (NBPs) and the Minimal Cell projects are two currently developed research lines belonging to the field of synthetic biology. The first deals with the investigation of structural and functional properties of de novo proteins with random sequences, selected and isolated using phage display methods. The minimal cell is the simplest cellular construct which displays living properties, such as self-maintenance, self-reproduction and evolvability. The semi-synthetic approach to minimal cells involves the use of extant genes and proteins in order to build a supramolecular construct based on lipid vesicles. Results and outlooks on these two research lines are shortly discussed, mainly focusing on their relevance to the origin of life studies.

  3. Annual review of research projects 1980

    International Nuclear Information System (INIS)

    Keam, D.W.

    1981-11-01

    The Australian Radiation Laboratory is a national centre concerned with the public and occupational health aspects of the use of both ionising and non-ionising radiation. Thirty two projects which were in progress during 1980 are described

  4. Battery Electric Vehicles: characteristics and research projects

    NARCIS (Netherlands)

    Besselink, I.J.M.

    2010-01-01

    This presentation discusses briefly the history of the electric car and its main characteristics. Two projects introduced: the battery electric VW Lupo EL and URE05e electric Formula Student racecar. Presentation slides.

  5. Proceedings of the public meeting to address a proposed federal radiation research agenda. Volume 2. Science projection papers

    International Nuclear Information System (INIS)

    1980-03-01

    Separate abstracts were prepared for the 14 science projection papers presented at a public meeting on March 10-11, 1980 to address a proposed federal radiation research agenda into the biological effects of ionizing radiation

  6. pClone: Synthetic Biology Tool Makes Promoter Research Accessible to Beginning Biology Students

    Science.gov (United States)

    Eckdahl, Todd; Cronk, Brian; Andresen, Corinne; Frederick, Paul; Huckuntod, Samantha; Shinneman, Claire; Wacker, Annie; Yuan, Jason

    2014-01-01

    The Vision and Change report recommended genuine research experiences for undergraduate biology students. Authentic research improves science education, increases the number of scientifically literate citizens, and encourages students to pursue research. Synthetic biology is well suited for undergraduate research and is a growing area of science. We developed a laboratory module called pClone that empowers students to use advances in molecular cloning methods to discover new promoters for use by synthetic biologists. Our educational goals are consistent with Vision and Change and emphasize core concepts and competencies. pClone is a family of three plasmids that students use to clone a new transcriptional promoter or mutate a canonical promoter and measure promoter activity in Escherichia coli. We also developed the Registry of Functional Promoters, an open-access database of student promoter research results. Using pre- and posttests, we measured significant learning gains among students using pClone in introductory biology and genetics classes. Student posttest scores were significantly better than scores of students who did not use pClone. pClone is an easy and affordable mechanism for large-enrollment labs to meet the high standards of Vision and Change. PMID:26086659

  7. SYNBIOCHEM Synthetic Biology Research Centre, Manchester – A UK foundry for fine and speciality chemicals production

    Directory of Open Access Journals (Sweden)

    Le Feuvre RA

    2016-12-01

    Full Text Available The UK Synthetic Biology Research Centre, SYNBIOCHEM, hosted by the Manchester Institute of Biotechnology at the University of Manchester is delivering innovative technology platforms to facilitate the predictable engineering of microbial bio-factories for fine and speciality chemicals production. We provide an overview of our foundry activities that are being applied to grand challenge projects to deliver innovation in bio-based chemicals production for industrial biotechnology.

  8. Technology Base Research Project for electrochemical energy storage

    Science.gov (United States)

    Kinoshita, K.

    1985-06-01

    The DOE Electrochemical Energy Storage Program is divided into two projects: (1) the exploratory technology development and testing (ETD) project and (2) the technology base research (TBR) project. The role of the TBR Project is to perform supporting research for the advanced battery systems under development by the ETD Project, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the TBR Project is to identify the most promising electrochemical technologies and transfer them to industry and/or the ETD Project for further development and scale-up. This report summarizes the research, financial, and management activities relevant to the TBR Project in CY 1984. General problem areas addressed by the project include identification of new electrochemical couples for advanced batteries, determination of technical feasibility of the new couples, improvements in battery components and materials, establishment of engineering principles applicable to electrochemical energy storage and conversion, and the assessment of fuel-cell technology for transportation applications. Major emphasis is given to applied research which will lead to superior performance and lower life-cycle costs. The TBR Project is divided into three major project elements: exploratory research, applied science research, and air systems research.

  9. Invited Review Article: Advanced light microscopy for biological space research

    Science.gov (United States)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; van Loon, Jack J. W. A.; Bereiter-Hahn, Juergen; Stelzer, Ernst H. K.

    2014-10-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  10. Invited Review Article: Advanced light microscopy for biological space research

    International Nuclear Information System (INIS)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; Loon, Jack J. W. A. van; Bereiter-Hahn, Juergen; Stelzer, Ernst H. K.

    2014-01-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy

  11. Invited Review Article: Advanced light microscopy for biological space research

    Energy Technology Data Exchange (ETDEWEB)

    De Vos, Winnok H., E-mail: winnok.devos@uantwerpen.be [Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp (Belgium); Cell Systems and Imaging Research Group, Department of Molecular Biotechnology, Ghent University, Ghent (Belgium); Beghuin, Didier [Lambda-X, Nivelles (Belgium); Schwarz, Christian J. [European Space Agency (ESA), ESTEC, TEC-MMG, Noordwijk (Netherlands); Jones, David B. [Institute for Experimental Orthopaedics and Biomechanics, Philipps University, Marburg (Germany); Loon, Jack J. W. A. van [Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center and Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam, Amsterdam (Netherlands); Bereiter-Hahn, Juergen; Stelzer, Ernst H. K. [Physical Biology, BMLS (FB15, IZN), Goethe University, Frankfurt am Main (Germany)

    2014-10-15

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  12. An Introductory "How-to" Guide for Incorporating Microbiome Research into Integrative and Comparative Biology.

    Science.gov (United States)

    Kohl, Kevin D

    2017-10-01

    Research on host-associated microbial communities has grown rapidly. Despite the great body of work, inclusion of microbiota-related questions into integrative and comparative biology is still lagging behind other disciplines. The purpose of this paper is to offer an introduction into the basic tools and techniques of host-microbe research. Specifically, what considerations should be made before embarking on such projects (types of samples, types of controls)? How is microbiome data analyzed and integrated with data measured from the hosts? How can researchers experimentally manipulate the microbiome? With this information, integrative and comparative biologists should be able to include host-microbe studies into their research and push the boundaries of both fields. © The Author 2017. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email: journals.permissions@oup.com.

  13. Using research to teach an "introduction to biological thinking".

    Science.gov (United States)

    Bell, Ellis

    2011-01-01

    A course design for first-year science students is described, where the focus is on the skills necessary to do science. The course uses original research projects, designed by the students, to teach a variety of skills including reading the scientific literature, hypothesis development and testing, experimental design, data analysis and interpretation, and quantitative skills and presentation of the research in a variety of formats. Copyright © 2011 Wiley Periodicals, Inc.

  14. Research Applications of Proteolytic Enzymes in Molecular Biology

    Directory of Open Access Journals (Sweden)

    József Tőzsér

    2013-11-01

    Full Text Available Proteolytic enzymes (also termed peptidases, proteases and proteinases are capable of hydrolyzing peptide bonds in proteins. They can be found in all living organisms, from viruses to animals and humans. Proteolytic enzymes have great medical and pharmaceutical importance due to their key role in biological processes and in the life-cycle of many pathogens. Proteases are extensively applied enzymes in several sectors of industry and biotechnology, furthermore, numerous research applications require their use, including production of Klenow fragments, peptide synthesis, digestion of unwanted proteins during nucleic acid purification, cell culturing and tissue dissociation, preparation of recombinant antibody fragments for research, diagnostics and therapy, exploration of the structure-function relationships by structural studies, removal of affinity tags from fusion proteins in recombinant protein techniques, peptide sequencing and proteolytic digestion of proteins in proteomics. The aim of this paper is to review the molecular biological aspects of proteolytic enzymes and summarize their applications in the life sciences.

  15. "Emancipatory Disability Research": Project or Process?

    Science.gov (United States)

    Barnes, Colin

    2002-01-01

    This article provides an overview of the core principles and implications of emancipatory disability research. It suggests the emancipatory research paradigm has begun to transform the material and social relations of research production and concludes by suggesting that emancipatory disability should be perceived as a process rather than a…

  16. Linguistic analysis of project ownership for undergraduate research experiences.

    Science.gov (United States)

    Hanauer, D I; Frederick, J; Fotinakes, B; Strobel, S A

    2012-01-01

    We used computational linguistic and content analyses to explore the concept of project ownership for undergraduate research. We used linguistic analysis of student interview data to develop a quantitative methodology for assessing project ownership and applied this method to measure degrees of project ownership expressed by students in relation to different types of educational research experiences. The results of the study suggest that the design of a research experience significantly influences the degree of project ownership expressed by students when they describe those experiences. The analysis identified both positive and negative aspects of project ownership and provided a working definition for how a student experiences his or her research opportunity. These elements suggest several features that could be incorporated into an undergraduate research experience to foster a student's sense of project ownership.

  17. ECBM research within the Dutch CATO Project

    NARCIS (Netherlands)

    Cuesta, P.T.; Wolf, K.-H.; Pagnier, H.; Spiers, C.; Bergen, F. van

    2005-01-01

    This chapter determines the technical and economical feasibility of Enhanced Coalbed Methane (ECBM) as a way to geologically sequester CO2. A number of field projects are taking place and much laboratory work has already been done, but still there is little or no fundamental understanding of the

  18. The Sunflower Cardiopulmonary Research Project of Children.

    Science.gov (United States)

    Greene, Leon

    A three year project designed to determine the value of a health program incorporating a cardiopulmonary fitness program is described. The instructional programs were in heart health, pulmonary health, nutrition, and physical fitness. A noncompetitive exercise and fitness period was employed in addition to the normal physical education time.…

  19. What Have Researchers Learned from Project STAR?

    Science.gov (United States)

    Schanzenbach, Diane Whitmore

    2007-01-01

    Project STAR (Student/Teacher Achievement Ratio) was a large-scale randomized trial of reduced class sizes in kindergarten through the third grade. Because of the scope of the experiment, it has been used in many policy discussions. For example, the California statewide class-size-reduction policy was justified, in part, by the successes of…

  20. The Systems Biology Research Tool: evolvable open-source software

    OpenAIRE

    Wright, J; Wagner, A

    2008-01-01

    Abstract Background Research in the field of systems biology requires software for a variety of purposes. Software must be used to store, retrieve, analyze, and sometimes even to collect the data obtained from system-level (often high-throughput) experiments. Software must also be used to implement mathematical models and algorithms required for simulation and theoretical predictions on the system-level. Results We introduce a free, easy-to-use, open-source, integrated software platform calle...

  1. BRIC-60: Biological Research in Canisters (BRIC)-60

    Science.gov (United States)

    Richards, Stephanie E. (Compiler); Levine, Howard G.; Romero, Vergel

    2016-01-01

    The Biological Research in Canisters (BRIC) is an anodized-aluminum cylinder used to provide passive stowage for investigations evaluating the effects of space flight on small organisms. Specimens flown in the BRIC 60 mm petri dish (BRIC-60) hardware include Lycoperscion esculentum (tomato), Arabidopsis thaliana (thale cress), Glycine max (soybean) seedlings, Physarum polycephalum (slime mold) cells, Pothetria dispar (gypsy moth) eggs and Ceratodon purpureus (moss).

  2. Research Applications of Proteolytic Enzymes in Molecular Biology

    OpenAIRE

    Mótyán, János András; Tóth, Ferenc; Tőzsér, József

    2013-01-01

    Proteolytic enzymes (also termed peptidases, proteases and proteinases) are capable of hydrolyzing peptide bonds in proteins. They can be found in all living organisms, from viruses to animals and humans. Proteolytic enzymes have great medical and pharmaceutical importance due to their key role in biological processes and in the life-cycle of many pathogens. Proteases are extensively applied enzymes in several sectors of industry and biotechnology, furthermore, numerous research applications ...

  3. Recent progress in structural biology: lessons from our research history.

    Science.gov (United States)

    Nitta, Ryo; Imasaki, Tsuyoshi; Nitta, Eriko

    2018-05-16

    The recent 'resolution revolution' in structural analyses of cryo-electron microscopy (cryo-EM) has drastically changed the research strategy for structural biology. In addition to X-ray crystallography and nuclear magnetic resonance spectroscopy, cryo-EM has achieved the structural analysis of biological molecules at near-atomic resolution, resulting in the Nobel Prize in Chemistry 2017. The effect of this revolution has spread within the biology and medical science fields affecting everything from basic research to pharmaceutical development by visualizing atomic structure. As we have used cryo-EM as well as X-ray crystallography since 2000 to elucidate the molecular mechanisms of the fundamental phenomena in the cell, here we review our research history and summarize our findings. In the first half of the review, we describe the structural mechanisms of microtubule-based motility of molecular motor kinesin by using a joint cryo-EM and X-ray crystallography method. In the latter half, we summarize our structural studies on transcriptional regulation by X-ray crystallography of in vitro reconstitution of a multi-protein complex.

  4. Dentistry in the future--on the role and goal of basic research in oral biology.

    Science.gov (United States)

    Mäkinen, K K

    1993-01-01

    Examination of the state of affairs of oral biology cannot be endeavoured without considering the mutual interactions and interdependencies of sciences, and without considering the impact human acts will exert on these developments. Oral biology deals with the biochemical, chemical, molecular biologic, general biologic and physical aspects of all processes that take place in the oral cavity, in the masticatory organ, and in tissues and body fluids that are associated with the above processes. Oral biology also reaps the harvest sown by (other) basic sciences. From the methodological point of view, oral biology is indistinguishable from basic sciences; it is the anatomical object that makes it specific. Oral biology cannot be regarded as "big science" (i.e. compared with the human genome project, space research, AIDS research etc.). This fact may preserve the attractiveness of oral biology. Important science--this concerns oral biology as well--still emerges in smaller settings, although there are omens that large research cartels will swallow larger and larger portions of research appropriations. A key to staying competitive is to use new science sources and--in some cases--to join bigger groups. Once upon a time oral biologists--or scientists in general--assumed that a record of solid accomplishments was sufficient to maintain research support. Today, in several countries, politics and public visibility unfortunately determine the funding privileges. Provided that human operations on earth will render future development of sciences possible, the future of oral biology will depend 1) on concomitant development in the above basic fields, and 2) on innovations in the individual psyches. This combination will unravel the structure of genes involved in the development and metabolism of oral processes, clone important salivary and connective tissue proteins, and control most important oral diseases. To achieve these goals, oral biology must attract young talent and

  5. US heat pump research and development projects, 1976-1986

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, K.H.

    1987-04-01

    This document, which is an updated version of US Heat Pump Research and Development Projects, published in August 1982 by the US Department of Energy, is a compilation of one-page summaries and publication and patent information for 233 individual research and development projects on heat pumps covering the years 1976 through 1986. The majority of the projects refer to heat pumps in space-conditioning applications. The document is intended to include information on all projects in the United States for which results are publicly available. Ten different indexes are included to aid the reader in locating specific projects.

  6. Multiweek cell culture project for use in upper-level biology laboratories.

    Science.gov (United States)

    Marion, Rebecca E; Gardner, Grant E; Parks, Lisa D

    2012-06-01

    This article describes a laboratory protocol for a multiweek project piloted in a new upper-level biology laboratory (BIO 426) using cell culture techniques. Human embryonic kidney-293 cells were used, and several culture media and supplements were identified for students to design their own experiments. Treatments included amino acids, EGF, caffeine, epinephrine, heavy metals, and FBS. Students researched primary literature to determine their experimental variables, made their own solutions, and treated their cells over a period of 2 wk. Before this, a sterile technique laboratory was developed to teach students how to work with the cells and minimize contamination. Students designed their experiments, mixed their solutions, seeded their cells, and treated them with their control and experimental media. Students had the choice of manipulating a number of variables, including incubation times, exposure to treatment media, and temperature. At the end of the experiment, students observed the effects of their treatment, harvested and dyed their cells, counted relative cell numbers in control and treatment flasks, and determined the ratio of living to dead cells using a hemocytometer. At the conclusion of the experiment, students presented their findings in a poster presentation. This laboratory can be expanded or adapted to include additional cell lines and treatments. The ability to design and implement their own experiments has been shown to increase student engagement in the biology-related laboratory activities as well as develop the critical thinking skills needed for independent research.

  7. Researchers' experiences, positive and negative, in integrative landscape projects

    NARCIS (Netherlands)

    Tress, B.; Tress, G.; Fry, G.

    2005-01-01

    Integrative (interdisciplinary and transdisciplinary) landscape research projects are becoming increasingly common. As a result, researchers are spending a larger proportion of their professional careers doing integrative work, participating in shifting interdisciplinary teams, and cooperating

  8. Division of Biological and Medical Research annual technical report, 1981

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1982-06-01

    This report summarizes research during 1981 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Low Level Radiation include comparison of lifetime effects in mice of low level neutron and gamma irradiation, delineation of the responses of dogs to continuous low level gamma irradiation, elucidation of mechanisms of radiation damage and repair in mammalian cells, and study of the genetic effects of high LET radiations. Carcinogenesis research addresses mechanisms of tumor initiation and promotion in rat liver, chemical carcinogenesis in cultured mammalian cells, and molecular and genetic mechanisms of chemical and ultraviolet mutagenesis in bacteria. Research in Toxicology uses a variety of cellular, whole animal, and chronobiological end points, chemical separations, and statistical models to evaluate the hazards and mechanisms of actions of metals, coal gasification by products, and other energy-related pollutants. Human Protein Index studies develop two-dimensional electrophoresis systems for diagnosis and detection of cancer and other disease. Biophysics research includes fundamental structural and biophysical investigations of immunoglobulins and key biological molecules using NMR, crystallographic, and x-ray and neutron small-angle scattering techniques. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies

  9. Division of Biological and Medical Research annual technical report, 1981

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.W. (ed.)

    1982-06-01

    This report summarizes research during 1981 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Low Level Radiation include comparison of lifetime effects in mice of low level neutron and gamma irradiation, delineation of the responses of dogs to continuous low level gamma irradiation, elucidation of mechanisms of radiation damage and repair in mammalian cells, and study of the genetic effects of high LET radiations. Carcinogenesis research addresses mechanisms of tumor initiation and promotion in rat liver, chemical carcinogenesis in cultured mammalian cells, and molecular and genetic mechanisms of chemical and ultraviolet mutagenesis in bacteria. Research in Toxicology uses a variety of cellular, whole animal, and chronobiological end points, chemical separations, and statistical models to evaluate the hazards and mechanisms of actions of metals, coal gasification by products, and other energy-related pollutants. Human Protein Index studies develop two-dimensional electrophoresis systems for diagnosis and detection of cancer and other disease. Biophysics research includes fundamental structural and biophysical investigations of immunoglobulins and key biological molecules using NMR, crystallographic, and x-ray and neutron small-angle scattering techniques. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  10. Distributed Research Project Scheduling Based on Multi-Agent Methods

    Directory of Open Access Journals (Sweden)

    Constanta Nicoleta Bodea

    2011-01-01

    Full Text Available Different project planning and scheduling approaches have been developed. The Operational Research (OR provides two major planning techniques: CPM (Critical Path Method and PERT (Program Evaluation and Review Technique. Due to projects complexity and difficulty to use classical methods, new approaches were developed. Artificial Intelligence (AI initially promoted the automatic planner concept, but model-based planning and scheduling methods emerged later on. The paper adresses the project scheduling optimization problem, when projects are seen as Complex Adaptive Systems (CAS. Taken into consideration two different approaches for project scheduling optimization: TCPSP (Time- Constrained Project Scheduling and RCPSP (Resource-Constrained Project Scheduling, the paper focuses on a multiagent implementation in MATLAB for TCSP. Using the research project as a case study, the paper includes a comparison between two multi-agent methods: Genetic Algorithm (GA and Ant Colony Algorithm (ACO.

  11. Synthesized research report in the second mid-term research phase. Mizunami Underground Research Laboratory project, Horonobe Underground Research Laboratory project and geo-stability project (Translated document)

    International Nuclear Information System (INIS)

    Hama, Katsuhiro; Sasao, Eiji; Iwatsuki, Teruki; Onoe, Hironori; Sato, Toshinori; Yasue, Kenichi; Asamori, Koichi; Niwa, Masakazu; Osawa, Hideaki; Nagae, Isako; Natsuyama, Ryoko; Fujita, Tomoo; Sasamoto, Hiroshi; Matsuoka, Toshiyuki; Takeda, Masaki; Aoyagi, Kazuhei; Nakayama, Masashi; Miyakawa, Kazuya; Ito, Hiroaki; Ohyama, Takuya; Senba, Takeshi; Amano, Kenji

    2016-08-01

    We have synthesized the research results from the Mizunami/Horonobe Underground Research Laboratories (URLs) and geo-stability projects in the second mid-term research phase. This report can be used as a technical basis for the Nuclear Waste Management Organization of Japan/Regulator at each decision point from siting to beginning of disposal (Principal Investigation to Detailed Investigation Phase). High-quality construction techniques and field investigation methods have been developed and implemented, which will be directly applicable to the National Disposal Program (together with general assessments of hazardous natural events and processes). Acquisition of technical knowledge on decisions of partial backfilling and final closure from actual field experiments in the Mizunami/Horonobe URLs will be crucial as the main theme for the next phases. (author)

  12. Researching wicked problems in a construction project

    DEFF Research Database (Denmark)

    Jacobsen, Peter Holm

    (Lave, 1988) and critical psychology (Axel, 2002; Dreier, 2008; Højholt & Kousholt, 2011). Situated learning theories have developed some valuable methodologies that can be used to study learning as an aspect of social practices and critical psychology have expanded theories of situated learning...... be elaborated more upon (Pink et. al., 2010). Getting access, formulating strategies for analyses, finding concepts and selecting methods such as participant observations and interviews are often problematic aspects, that influences the knowledge that researchers produces in a number of ways that relates...... to empirical research. I will argue that uncertainty is an important aspect of doing empirical research because the empirical research is a part of a situated learning process and that uncertain situations are a central part of conducting empirical research. I will use an example from my study of the early...

  13. Division of Biological and Medical Research research summary 1984-1985

    Energy Technology Data Exchange (ETDEWEB)

    Barr, S.H. (ed.)

    1985-08-01

    The Division of Biological and Medical Research at Argonne National Laboratory conducts multidisciplinary research aimed at defining the biological and medical hazards to man from energy technologies and new energy options. These technically oriented studies have a strong base in fundamental research in a variety of scientific disciplines, including molecular and cellular biology, biophysics, genetics, radiobiology, pharmacology, biochemistry, chemistry, environmental toxicology, and epidemiology. This research summary is organized into six parts. The first five parts reflect the Divisional structure and contain the scientific program chapters, which summarize the activities of the individual groups during the calendar year 1984 and the first half of 1985. To provide better continuity and perspective, previous work is sometimes briefly described. Although the summaries are short, efforts have been made to indicate the range of research activities for each group.

  14. Division of Biological and Medical Research research summary 1984-1985

    International Nuclear Information System (INIS)

    Barr, S.H.

    1985-08-01

    The Division of Biological and Medical Research at Argonne National Laboratory conducts multidisciplinary research aimed at defining the biological and medical hazards to man from energy technologies and new energy options. These technically oriented studies have a strong base in fundamental research in a variety of scientific disciplines, including molecular and cellular biology, biophysics, genetics, radiobiology, pharmacology, biochemistry, chemistry, environmental toxicology, and epidemiology. This research summary is organized into six parts. The first five parts reflect the Divisional structure and contain the scientific program chapters, which summarize the activities of the individual groups during the calendar year 1984 and the first half of 1985. To provide better continuity and perspective, previous work is sometimes briefly described. Although the summaries are short, efforts have been made to indicate the range of research activities for each group

  15. SAGE as a Source for Undergraduate Research Projects

    Science.gov (United States)

    Hutz, Benjamin

    2017-01-01

    This article examines the use of the computer algebra system SAGE for undergraduate student research projects. After reading this article, the reader should understand the benefits of using SAGE as a source of research projects and how to commence working with SAGE. The author proposes a tiered working group model to allow maximum benefit to the…

  16. The Bitterroot Ecosystem Management Research Project: What we have learned

    Science.gov (United States)

    Helen Y. Smith

    2000-01-01

    The varied topics presented in these symposium proceedings represent the diverse nature of the Bitterroot Ecosystem Management Research Project (BEMRP). Separated into six sections, the papers cover the different themes researched by BEMRP collaborators as well as brief overviews of five other ecosystem management projects. The sections are: Understanding the Ecosystem...

  17. Research Applications for Teaching (RAFT) Project. Final Report.

    Science.gov (United States)

    Thomson, James R., Jr.; Handley, Herbert M.

    A report is given of the development and progress of the Research Applications for Teaching (RAFT) project, developed at Mississippi State University. Based upon research findings relative to effective teaching and effective schooling, five curriculum modules were prepared and implemented in instruction. In the second year of the project the…

  18. Understanding the selection processes of public research projects

    NARCIS (Netherlands)

    Materia, V.C.; Pascucci, S.; Kolympiris, C.

    2015-01-01

    This paper analyses factors that affect the funding of agricultural research projects by regional governments and other regional public authorities. We study the selection process of agricultural research projects funded by the emilia Romagna regional government in Italy, which follows funding

  19. Defining and implementing a model for pharmacy resident research projects

    Directory of Open Access Journals (Sweden)

    Dick TB

    2015-09-01

    Full Text Available Objective: To describe a standard approach to provide a support structure for pharmacy resident research that emphasizes self-identification of a residency research project. Methods: A subcommittee of the residency advisory committee was formed at our institution. The committee was initially comprised of 2 clinical pharmacy specialists, 1 drug information pharmacist, and 2 pharmacy administrators. The committee developed research guidelines that are distributed to residents prior to the residency start that detail the research process, important deadlines, and available resources. Instructions for institutional review board (IRB training and deadlines for various assignments and presentations throughout the residency year are clearly defined. Residents conceive their own research project and emphasis is placed on completing assignments early in the residency year. Results: In the 4 years this research process has been in place, 15 of 16 (94% residents successfully identified their own research question. All 15 residents submitted a complete research protocol to the IRB by the August deadline. Four residents have presented the results of their research at multi-disciplinary national professional meetings and 1 has published a manuscript. Feedback from outgoing residents has been positive overall and their perceptions of their research projects and the process are positive. Conclusion: Pharmacy residents selecting their own research projects for their residency year is a feasible alternative to assigning or providing lists of research projects from which to select a project.

  20. Norwegian computers in European energy research project

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    16 NORD computers have been ordered for the JET data acquisition and storage system. The computers will be arranged in a 'double star' configuration, developed by CERN. Two control consoles each have their own computer. All computers for communication, control, diagnostics, consoles and testing are NORD-100s while the computer for data storage and analysis is a NORD-500. The operating system is SINTRAN CAMAC SERIAL HIGHWAY with fibre optics to be used for long communications paths. The programming languages FORTRAN, NODAL, NORD PL, PASCAL and BASIC may be used. The JET project and TOKAMAK type machines are briefly described. (JIW)

  1. Environmental setting for biological variability at PTEPBN project of West Kalimantan

    International Nuclear Information System (INIS)

    Suwadji, E.; Endrawanto

    1995-01-01

    Biological variability was needed in the arrangement of environmental evaluation study on term of environmental impact assessment. The activity was carried out at PTEPBN project to find out and to predict the environmental setting of outgoing and ongoing project as well as the project operational after post construction. Methods to find out the environmental setting on biological variability were proposed. Based on the observation data on its terrestrial and aquatic flora and fauna, it can be concluded that terrestrial flora was found at fair to good value, terrestrial fauna at fair to good whereas aquatic flora and fauna at good. (author). 8 refs, 7 tabs, 1 fig

  2. Division of Biological and Medical Research annual technical report 1982

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1983-05-01

    This report summarizes research during 1982 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Carcinogenesis address mechanisms of chemical and radiation carcinogenesis including the processes of tumor initiation and promotion. The studies employ rat liver and mouse skin models as well as human rodent cell culture systems. The use of liposomes for metal mobilization is also explored. Low Level Radiation studies include delineation of the hematopoietic and other responses of dogs to continuous low level gamma irradiation, comparison of lifetime effects in mice of low level neutron and gamma irradiation, and study of the genetic effects of high LET radiation. Molecular Biology research develops two-dimensional electrophoresis systems for diagnosis and detection of cancer and other diseases. Fundamental structural and biophysical investigations of immunoglobulins and other key proteins are included, as are studies of cell growth, and of molecular and cellular effects of solar uv light. Research in Toxicology uses cellular, physiological, whole animal, and chronobiological end points and chemical separations to elucidate mechanisms and evaluate hazards of coal conversion by-products, actinides, and toxic metals. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies

  3. Division of Biological and Medical Research annual technical report 1982

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.W. (ed.)

    1983-05-01

    This report summarizes research during 1982 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Carcinogenesis address mechanisms of chemical and radiation carcinogenesis including the processes of tumor initiation and promotion. The studies employ rat liver and mouse skin models as well as human rodent cell culture systems. The use of liposomes for metal mobilization is also explored. Low Level Radiation studies include delineation of the hematopoietic and other responses of dogs to continuous low level gamma irradiation, comparison of lifetime effects in mice of low level neutron and gamma irradiation, and study of the genetic effects of high LET radiation. Molecular Biology research develops two-dimensional electrophoresis systems for diagnosis and detection of cancer and other diseases. Fundamental structural and biophysical investigations of immunoglobulins and other key proteins are included, as are studies of cell growth, and of molecular and cellular effects of solar uv light. Research in Toxicology uses cellular, physiological, whole animal, and chronobiological end points and chemical separations to elucidate mechanisms and evaluate hazards of coal conversion by-products, actinides, and toxic metals. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  4. Designing and Conducting Health Systems Research Projects ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Giving girls and women the power to decide. Addressing Africa's unmet need for family planning by intensifying sexual and reproductive and adolescent health research. View moreGiving girls and women the power to decide ...

  5. Research Projects, Technical Reports and Publications

    Science.gov (United States)

    Oliger, Joseph

    1996-01-01

    The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. A flexible scientific staff is provided through a university faculty visitor program, a post doctoral program, and a student visitor program. Not only does this provide appropriate expertise but it also introduces scientists outside of NASA to NASA problems. A small group of core RIACS staff provides continuity and interacts with an ARC technical monitor and scientific advisory group to determine the RIACS mission. RIACS activities are reviewed and monitored by a USRA advisory council and ARC technical monitor. Research at RIACS is currently being done in the following areas: Advanced Methods for Scientific Computing High Performance Networks During this report pefiod Professor Antony Jameson of Princeton University, Professor Wei-Pai Tang of the University of Waterloo, Professor Marsha Berger of New York University, Professor Tony Chan of UCLA, Associate Professor David Zingg of University of Toronto, Canada and Assistant Professor Andrew Sohn of New Jersey Institute of Technology have been visiting RIACS. January 1, 1996 through September 30, 1996 RIACS had three staff scientists, four visiting scientists, one post-doctoral scientist, three consultants, two research associates and one research assistant. RIACS held a joint workshop with Code 1 29-30 July 1996. The workshop was held to discuss needs and opportunities in basic research in

  6. Budgeting, funding, and managing clinical research projects.

    Science.gov (United States)

    Hatfield, Elizabeth; Dicks, Elizabeth; Parfrey, Patrick

    2009-01-01

    Large, integrated multidisciplinary teams have become recognized as an efficient means by which to drive innovation and discovery in clinical research. This chapter describes how to budget and fund these large studies and effectively manage the large, often dispersed teams involved. Sources of funding are identified; budget development, justification, reporting, financial governance, and accountability are described; in addition to the creation and management of the multidisciplinary team that will implement the research plan.

  7. Looking through the Lens: Adapting and Modifying Photovoice Projects for Active Learning and Engagement in Biology

    OpenAIRE

    Karobi Moitra

    2016-01-01

    Photovoice projects traditionally include original visual imagery and minimal text to tell a powerful story. Photovoice student projects have been utilized in the health and social sciences to involve students with the local community and also in community-based projects to help at-risk youth call attention to their community problems, such as disease and drug use. The tool of the photovoice can be used in the biology classroom to engage students in the active learning process through communi...

  8. Use of synchrotron radiation in radiation biology research

    International Nuclear Information System (INIS)

    Yamada, Takeshi

    1981-01-01

    Synchrotron radiation (SR) holds great expectation as a new research tool in the new areas of material science, because it has the continuous spectral distribution from visible light to X-ray, and its intensity is 10 2 to 10 3 times as strong as that of conventional radiation sources. In the National Laboratory for High Energy Physics, a synchrotron radiation experimental facility has been constructed, which will start operation in fiscal 1982. With this SR, the photons having the wavelength in undeveloped region from vacuum ultraviolet to soft X-ray are obtained as intense mono-wavelength light. The SR thus should contribute to the elucidation of the fundamentals in the biological action of radiation. The following matters are described: synchrotron radiation, experimental facility using SR, electron storage ring, features of SR, photon factory plan and synchrotron radiation experimental facility, utilization of SR in radiation biology field. (J.P.N.)

  9. Desegregating undergraduate mathematics and biology--interdisciplinary instruction with emphasis on ongoing biomedical research.

    Science.gov (United States)

    Robeva, Raina

    2009-01-01

    The remarkable advances in the field of biology in the last decade, specifically in the areas of biochemistry, genetics, genomics, proteomics, and systems biology, have demonstrated how critically important mathematical models and methods are in addressing questions of vital importance for these disciplines. There is little doubt that the need for utilizing and developing mathematical methods for biology research will only grow in the future. The rapidly increasing demand for scientists with appropriate interdisciplinary skills and knowledge, however, is not being reflected in the way undergraduate mathematics and biology courses are structured and taught in most colleges and universities nationwide. While a number of institutions have stepped forward and addressed this need by creating and offering interdisciplinary courses at the juncture of mathematics and biology, there are still many others at which there is little, if any, interdisciplinary interaction between the curricula. This chapter describes an interdisciplinary course and a textbook in mathematical biology developed collaboratively by faculty from Sweet Briar College and the University of Virginia School of Medicine. The course and textbook are designed to provide a bridge between the mathematical and biological sciences at the lower undergraduate level. The course is developed for and is being taught in a liberal arts setting at Sweet Briar College, Virginia, but some of the advanced modules are used in a course at the University of Virginia for advanced undergraduate and beginning graduate students. The individual modules are relatively independent and can be used as stand-alone projects in conventional mathematics and biology courses. Except for the introductory material, the course and textbook topics are based on current biomedical research.

  10. Transforming Roles: Canadian Academic Librarians Embedded in Faculty Research Projects

    Science.gov (United States)

    Bedi, Shailoo; Waldie, Christine

    2017-01-01

    Academic librarians have always played an important role in providing research services and research-skills development to faculty in higher education. But that role is evolving to include the academic librarian as a unique and necessary research partner, practitioner, and participant in collaborative, grant-funded research projects. This article…

  11. Scientific projection paper on biologic effects of ionizing radiation

    International Nuclear Information System (INIS)

    Matanoski, G.

    1980-01-01

    There is widespread knowledge about the effects of radiation in human populations but the studies have had some limitations which have left gaps in our knowledge. Most populations have had exposure to high doses with little information on the effect of dose rate. The characteristics of the populations have been restricted by the location of the disaster, the occupational limitations, or the basic risks associated with the under-lying disease for which radiation was given. All doses have been estimated and such values are subject to marked variability particularly when they rely on sources of data such as hospital records. The biological data although extensive have several deficits in information. Which are the sites in which cancer is produced by irradiation and what are the cell types which are produced. The sensitivity of various tissues and organs are not similar and it is important to rank them according to susceptibility. This has been done in the past but the results are not complete for all cell types and organs. The temporal patterns for tumor development, the latent period, the period of expressed excess, the life-time risks need to be defined more precisely for the cancers. Many populations have not been followed long enough to express the complete risk

  12. AVST Morphing Project Research Summaries in Fiscal Year 2001

    Science.gov (United States)

    McGowan, Anna-Maria R.

    2002-01-01

    The Morphing project at the National Aeronautics and Space Agency's Langley Research Center is part of the Aerospace Vehicle Systems Program Office that conducts fundamental research on advanced technologies for future flight vehicles. The objectives of the Morphing project are to develop and assess advanced technologies and integrated component concepts to enable efficient, multi-point adaptability in air and space vehicles. In the context of the project, the word "morphing" is defined as "efficient, multi-point adaptability" and may include micro or macro, structural or fluidic approaches. The current document on the Morphing project is a compilation of research summaries and other information on the project from fiscal year 2001. The focus of this document is to provide a brief overview of the project content, technical results and lessons learned from fiscal year 2001.

  13. NASA's Morphing Project Research Summaries in Fiscal Year 2002

    Science.gov (United States)

    McGowan, Anna-Maria R.; Waszak, Martin R.

    2005-01-01

    The Morphing Project at the National Aeronautics and Space Agency s (NASA) Langley Research Center (LaRC) is part of the Breakthrough Vehicle Technologies Project, Vehicle Systems Program that conducts fundamental research on advanced technologies for future flight vehicles. The objectives of the Morphing Project are to develop and assess the advanced technologies and integrated component concepts to enable efficient, multi-point adaptability of flight vehicles; primarily through the application of adaptive structures and adaptive flow control to substantially alter vehicle performance characteristics. This document is a compilation of research summaries and other information on the project for fiscal year 2002. The focus is to provide a brief overview of the project content, technical results and lessons learned. At the time of publication, the Vehicle Systems Program (which includes the Morphing Project) is undergoing a program re-planning and reorganization. Accordingly, the programmatic descriptions of this document pertain only to the program as of fiscal year 2002.

  14. Synthesized research report in the second mid-term research phase. Mizunami Underground Research Laboratory project, Horonobe Underground Research Laboratory project and geo-stability project

    International Nuclear Information System (INIS)

    Hama, Katsuhiro; Sasao, Eiji; Iwatsuki, Teruki; Saegusa, Hiromitsu; Sato, Toshinori; Umeda, Koji; Yasue, Kenichi; Asamori, Koichi; Osawa, Hideaki; Koide, Kaoru; Nagae, Isako; Natsuyama, Ryoko; Mizuno, Takashi; Fujita, Tomoo; Sasamoto, Hiroshi; Matsuoka, Toshiyuki; Yokota, Hideharu; Ishii, Eiichi; Aoyagi, Kazuhei; Nakayama, Masashi; Ito, Hiroaki; Tsusaka, Kimikazu; Ohyama, Takuya; Senba, Takeshi; Amano, Kenji

    2015-08-01

    We have synthesised the research results from Mizunami/Horonobe URLs and geo-stability projects in the second mid-term research phase. It could be used as technical bases for NUMO/Regulator in each decision point from siting to beginning of disposal (Principal Investigation to Detailed Investigation Phase). High quality construction techniques and field investigation methods have been developed and implemented and these will be directly applicable to the National Disposal Program (along with general assessments of hazardous natural events and processes). It will be crucial to acquire technical knowledge on decisions of partial backfilling and final closure by actual field experiments in Mizunami/Horonobe URLs as main themes for the next phases. (author)

  15. Diversity in research projects - A key to success?

    Science.gov (United States)

    Henkel, Daniela; Eisenhauer, Anton; Taubner, Isabelle

    2017-04-01

    According to demographers, psychologists, sociologists and economists diverse groups, which are groups of different race, ethnicity, gender and sexual orientation, are more innovative than homogeneous groups. This is also true for groups working together in research collaborations and international cooperation involving a culturally and functionally diverse mix of individuals who have to be integrated into an effective unit - a project team. If the goal is scientific excellence, diversity should be an essential ingredient to conduct science on high level productivity, quality and innovation. Effective teamwork is a key to project success and prime responsibilities of the project manager. Therefore, the project manager has to take into consideration different characteristics such as cultures, languages, and different values related to individual project partners. Here we show how diversity can affect the performance of a research project. Furthermore, the presentation indicates skills and abilities which are required for the management in order to deal also with the challenges of diversity in research projects. The presentation is based on insights experienced in the context of an Innovative Training Network (ITN) project within Marie Skłodowska-Curie Actions of the European HORIZON 2020 program and TRION a Collaborative Research Project in the Framework of the Trilateral Program of the German Research Foundation.

  16. Research projects in family medicine funded by the European Union.

    Science.gov (United States)

    Pavličević, Ivančica; Barać, Lana

    2014-01-01

    This study aimed at synthesizing funding opportunities in the field of family medicine by determining the number of family medicine projects, as well as number of project leaderships and/ or participations by each country. This was done in order to encourage inclusion of physicians in countries with underdeveloped research networks in successful research networks or to encourage them to form new ones. We searched the Community Research and Development Information Service project database in February 2013. Study covered the period from years 1992 - 2012, selecting the projects within the field of general/family medicine. The search was conducted in February 2013. First search conducted in the CORDIS database came up with a total of 466 projects. After excluding 241 projects with insufficient data, we analysed 225 remaining projects; out of those, 22 (9.8%) were in the field of family medicine and 203 (90.2%) were from other fields of medicine. Sorted by the number of projects per country, Dutch institutions had the highest involvement in family medicine projects and were partners or coordinators in 18 out of 22 selected projects (81.8%), followed by British institutions with 15 (68.8%), and Spanish with 10 projects (45.5%). Croatia was a partner in a single FP7 Health project. Research projects in family medicine funded by the European Union show significant differences between countries. Constant and high-quality international cooperation in family medicine is the prerequisite for improvement and development of scientific research and the profession. Copyright © 2014 by Academy of Sciences and Arts of Bosnia and Herzegovina.

  17. Leading Undergraduate Research Projects in Mathematical Modeling

    Science.gov (United States)

    Seshaiyer, Padmanabhan

    2017-01-01

    In this article, we provide some useful perspectives and experiences in mentoring students in undergraduate research (UR) in mathematical modeling using differential equations. To engage students in this topic, we present a systematic approach to the creation of rich problems from real-world phenomena; present mathematical models that are derived…

  18. Research in thermal biology: Burning questions for coldwater stream fishes

    Science.gov (United States)

    McCullough, D.A.; Bartholow, J.M.; Jager, H.I.; Beschta, R.L.; Cheslak, E.F.; Deas, M.L.; Ebersole, J.L.; Foott, J.S.; Johnson, S.L.; Marine, K.R.; Mesa, M.G.; Petersen, J.H.; Souchon, Y.; Tiffan, K.F.; Wurtsbaugh, W.A.

    2009-01-01

    With the increasing appreciation of global warming impacts on ecological systems, in addition to the myriad of land management effects on water quality, the number of literature citations dealing with the effects of water temperature on freshwater fish has escalated in the past decade. Given the many biological scales at which water temperature effects have been studied, and the growing need to integrate knowledge from multiple disciplines of thermal biology to fully protect beneficial uses, we held that a survey of the most promising recent developments and an expression of some of the remaining unanswered questions with significant management implications would best be approached collectively by a diverse research community. We have identified five specific topic areas of renewed research where new techniques and critical thought could benefit coldwater stream fishes (particularly salmonids): molecular, organism, population/species, community and ecosystem, and policy issues in water quality. Our hope is that information gained through examination of recent research fronts linking knowledge at various scales will prove useful in managing water quality at a basin level to protect fish populations and whole ecosystems. Standards of the past were based largely on incipient lethal and optimum growth rate temperatures for fish species, while future standards should consider all integrated thermal impacts to the organism and ecosystem. ?? Taylor and Francis Group, LLC.

  19. Biological air contamination in elderly care centers: geria project.

    Science.gov (United States)

    Aguiar, Lívia; Mendes, Ana; Pereira, Cristiana; Neves, Paula; Mendes, Diana; Teixeira, João Paulo

    2014-01-01

    Indoor air quality (IAQ) affects health particularly in susceptible individuals such as the elderly. It has been estimated that the older population spends approximately 19-20 h/d indoors, and the majority of the elderly spend all of their time indoors in elderly care centers (ECC). Older individuals may be particularly at risk of exposure to detrimental effects from pollutants, even at low concentrations, due to common and multiple underlying chronic diseases that increase susceptibility. This study, aimed to assess the impact of indoor biological agents in 22 ECC located in Porto, was conducted during summer and winter from November 2011 to August 2013 at a total of 141 areas within dining rooms, drawing rooms, medical offices, and bedrooms (including the bedridden). Air sampling was carried out with a microbiological air sampler (Merck MAS-100) and using tryptic soy agar for bacteria and malt extract agar for fungi. The results obtained were compared with the recently revised Portuguese standards. In winter, mean fungi concentration exceeded reference values, while bacteria concentrations were within the new standards in both seasons. The main fungi species found indoors were Cladosporium (73%) in summer and Penicillium (67%) in winter. Aspergillus fumigatus, Aspergillus niger, and Aspergillus flavus, known potential pathogenic/toxigenic species, were also identified. Although the overall rate and mean values of bacteria and fungi found in ECC indoor air met Portuguese legislation, some concern is raised by the presence of pathogenic microorganisms. Simple measures, like opening windows and doors to promote air exchange and renewal, may improve effectiveness in enhancing IAQ.

  20. A ProCoS II Project Final Report: ESPRIT Basic Research project 707

    DEFF Research Database (Denmark)

    Bowen, J. P.; Hoare, C. A. R.; Langmaack, Hans

    1996-01-01

    An overview of the research and associated activities of the Europeancollaborative ESPRIT Basic Research ProCoS II project (no. 7071) on``Provably Correct Systems'' which ran from 1992 to 1995 is presented.This was a follow-on project to ProCoS (no. 3104) and ran inparallel with the ProCoS Working...

  1. Caenorhabditis elegans, a Biological Model for Research in Toxicology.

    Science.gov (United States)

    Tejeda-Benitez, Lesly; Olivero-Verbel, Jesus

    2016-01-01

    Caenorhabditis elegans is a nematode of microscopic size which, due to its biological characteristics, has been used since the 1970s as a model for research in molecular biology, medicine, pharmacology, and toxicology. It was the first animal whose genome was completely sequenced and has played a key role in the understanding of apoptosis and RNA interference. The transparency of its body, short lifespan, ability to self-fertilize and ease of culture are advantages that make it ideal as a model in toxicology. Due to the fact that some of its biochemical pathways are similar to those of humans, it has been employed in research in several fields. C. elegans' use as a biological model in environmental toxicological assessments allows the determination of multiple endpoints. Some of these utilize the effects on the biological functions of the nematode and others use molecular markers. Endpoints such as lethality, growth, reproduction, and locomotion are the most studied, and usually employ the wild type Bristol N2 strain. Other endpoints use reporter genes, such as green fluorescence protein, driven by regulatory sequences from other genes related to different mechanisms of toxicity, such as heat shock, oxidative stress, CYP system, and metallothioneins among others, allowing the study of gene expression in a manner both rapid and easy. These transgenic strains of C. elegans represent a powerful tool to assess toxicity pathways for mixtures and environmental samples, and their numbers are growing in diversity and selectivity. However, other molecular biology techniques, including DNA microarrays and MicroRNAs have been explored to assess the effects of different toxicants and samples. C. elegans has allowed the assessment of neurotoxic effects for heavy metals and pesticides, among those more frequently studied, as the nematode has a very well defined nervous system. More recently, nanoparticles are emergent pollutants whose toxicity can be explored using this nematode

  2. Biomass Gasification Research and Development Project

    Energy Technology Data Exchange (ETDEWEB)

    Ahring, Birgitte K. [Washington State Univ., Pullman, WA (United States)

    2014-07-22

    The overall objective of the BioChemCat project was to demonstrate the feasibility of using Advanced Wet Oxidation Steam-Explosion (AWEx) process to open and solubilize lignocellulosic biomass (LBM) coupled to an innovative mixed culture fermentation technology capable of producing a wide range of volatile fatty acids (VFAs) from all sugars present in LBM. The VFAs will then be separated and converted to hydrocarbon biofuel through catalytic upgrading. By continuously removing VFAs as they are produced (extractive fermentation), we were able to recover the VFAs while both eliminating the need for pH adjustment and increasing the fermentation productivity. The recovered VFAs were then esterified and upgraded to hydrocarbon fuels through a parallel series of hydrogenolysis/decarboxylation and dehydration reactions. We also demonstrated that a portion of the residual lignin fraction was solubilized and converted into VFAs, also improving the yields of VFAs. The remaining lignin fraction was then shown to be available (after dewatering and drying) for use as a lignin-enriched fuel pellet or as a feedstock for further processing.

  3. Project Report: Undergraduate Student Research Program (USRP)

    Science.gov (United States)

    Gavin, Patricia

    2011-01-01

    To better understand geochemical processes occurring on Europa's seafloor, we investigated the effects of varying Fe?content in the seafloor rock and varying temperature. Iron is important in such geochemical processes as the production of methane through serpentinization (e.g. Allen and Seyfried, 2003) and can be a nutrient for microbes (Russell and Hall, 2006; Park and Kim, 2001). It can also offer clues as to the state of differentiation of Europa's core/mantle. If Europa is fully differentiated and contains an iron core, we would expect there to be little iron in the mantle and ocean floor whereas a homogeneous Europa would have iron evenly dispersed throughout the ocean floor. Furthermore, the composition of the ocean is a result of water?rock interactions at the seafloor. This project investigated the effects of temperature on geochemical processes, comparing high temperature (> 250oC) hydrothermal vents (Kelley et al., 2001) to lower temperature (20oC) cold seeps (e.g. Orphan et al., 2002).

  4. Small Hydropower Research and Development Technology Project

    Energy Technology Data Exchange (ETDEWEB)

    Blackmore, Mo [Near Space Systems, Inc.

    2013-12-06

    The objective of this work was to investigate, develop, and validate the next generation of small hydroturbine generator designs that maximize the energy transfer from flowing water to electrical power generation. What resulted from this effort was the design of a new technology hydroturbine that Near Space Systems (NSS) has named the Star*Stream© Hydroturbine. Using a design that eliminates nearly all of the shortfalls of conventional hydroturbines, the Star*Stream© Hydroturbine employs a new mechanical-to-electrical energy transfer hydro design that operates without lubrication of any kind, and does not introduce foreign chemicals or particulate matter from oil or drive shaft seal degradation into the hydro ecology. In its unique configuration, the Star*Stream© Hydroturbine is nearly environmentally inert, without the negative aspects caused by interrupting the ecological continuity, i.e., disruptions to sedimentation, water quality, habitat changes, human displacement, fish migration, etc., - while it ensures dramatically reduced timeframes to project completion. While a remarkable reduction in LCOE resulting from application of the Star*Stream© Hydroturbine technology has been the core achievement of the this effort, there have been numerous technological breakthroughs from the development effort.

  5. Biorefinery and Carbon Cycling Research Project

    Energy Technology Data Exchange (ETDEWEB)

    Das, K. C., Adams; Thomas, T; Eiteman, Mark A; Kastner, James R; Mani, Sudhagar; Adolphson, Ryan

    2012-06-08

    In this project we focused on several aspects of technology development that advances the formation of an integrated biorefinery. These focus areas include: [ 1] pretreatment of biomass to enhance quality of products from thermochemical conversion; [2] characterization of and development of coproduct uses; [3] advancement in fermentation of lignocellulosics and particularly C5 and C6 sugars simultaneously, and [ 4] development of algal biomass as a potential substrate for the biorefinery. These advancements are intended to provide a diverse set of product choices within the biorefinery, thus improving the cost effectiveness of the system. Technical effectiveness was demonstrated in the thermochemical product quality in the form of lower tar production, simultaneous of use of multiple sugars in fermentation, use ofbiochar in environmental (ammonia adsorption) and agricultural applications, and production of algal biomass in wastewaters. Economic feasibility of algal biomass production systems seems attractive, relative to the other options. However, further optimization in all paths, and testing/demonstration at larger scales are required to fully understand the economic viabilities. The coproducts provide a clear picture that multiple streams of value can be generated within an integrated biorefinery, and these include fuels and products.

  6. The Medline/full-text research project.

    Science.gov (United States)

    McKinin, E J; Sievert, M; Johnson, E D; Mitchell, J A

    1991-05-01

    This project was designed to test the relative efficacy of index terms and full-text for the retrieval of documents in those MEDLINE journals for which full-text searching was also available. The full-text files used were MEDIS from Mead Data Central and CCML from BRS Information Technologies. One hundred clinical medical topics were searched in these two files as well as the MEDLINE file to accumulate the necessary data. It was found that full-text identified significantly more relevant articles than did the indexed file, MEDLINE. The full-text searches, however, lacked the precision of searches done in the indexed file. Most relevant items missed in the full-text files, but identified in MEDLINE, were missed because the searcher failed to account for some aspect of natural language, used a logical or positional operator that was too restrictive, or included a concept which was implied, but not expressed in the natural language. Very few of the unique relevant full-text citations would have been retrieved by title or abstract alone. Finally, as of July, 1990 the more current issue of a journal was just as likely to appear in MEDLINE as in one of the full-text files.

  7. Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements

    Science.gov (United States)

    Kohl, Alain; Pondeville, Emilie; Schnettler, Esther; Crisanti, Andrea; Supparo, Clelia; Christophides, George K.; Kersey, Paul J.; Maslen, Gareth L.; Takken, Willem; Koenraadt, Constantianus J. M.; Oliva, Clelia F.; Busquets, Núria; Abad, F. Xavier; Failloux, Anna-Bella; Levashina, Elena A.; Wilson, Anthony J.; Veronesi, Eva; Pichard, Maëlle; Arnaud Marsh, Sarah; Simard, Frédéric; Vernick, Kenneth D.

    2016-01-01

    Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is increasingly common. Novel tools for genetic manipulation of vectors, use of Wolbachia endosymbiotic bacteria, and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies, adding to strong interest in vector biology and genetics as well as vector–pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructure investment should be informed by the research community. A survey initiated by the European Horizon 2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key activities that are needed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such activities to be carried out. We summarize the most important findings of the survey which in particular reflect the priorities of researchers in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations. PMID:27677378

  8. Continuing training program in radiation protection in biological research centers

    International Nuclear Information System (INIS)

    Escudero, R.; Hidalgo, R.M.; Usera, F.; Macias, M.T.; Mirpuri, E.; Perez, J.; Sanchez, A.

    2008-01-01

    The use of ionizing radiation in biological research has many specific characteristics. A great variety of radioisotopic techniques involve unsealed radioactive sources, and their use not only carries a risk of irradiation, but also a significant risk of contamination. Moreover, a high proportion of researchers are in training and the labor mobility rate is therefore high. Furthermore, most newly incorporated personnel have little or no previous training in radiological protection, since most academic qualifications do not include training in this discipline. In a biological research center, in addition to personnel whose work is directly associated with the radioactive facility (scientific-technical personnel, operators, supervisors), there are also groups of support personnel The use of ionizing radiation in biological research has many specific characteristics. A great variety of radioisotopic techniques involve unsealed radioactive sources, and their use not only carries a risk of irradiation, but also a significant risk of contamination. Moreover, a high proportion of researchers are in training and the labor mobility rate is therefore high. Furthermore, most newly incorporated personnel have little or no previous training in radiological protection, since most academic qualifications do not include training in this discipline. In a biological research center, in addition to personnel whose work is directly associated with the radioactive facility (scientific-technical personnel, operators, supervisors), there are also groups of support personnel maintenance and instrumentation workers, cleaners, administrative personnel, etc. who are associated with the radioactive facility indirectly. These workers are affected by the work in the radioactive facility to varying degrees, and they therefore also require information and training in radiological protection tailored to their level of interaction with the installation. The aim of this study was to design a

  9. "Biology Education"--An Emerging Interdisciplinary Area of Research

    Science.gov (United States)

    Rutledge, Michael

    2013-01-01

    The growing number of faculty positions in biology education, the formation of professional societies focused specifically on biology education, and the increasing number of publications in biology education over the past decade

  10. Human-Robot Interaction Directed Research Project

    Science.gov (United States)

    Rochlis, Jennifer; Ezer, Neta; Sandor, Aniko

    2011-01-01

    Human-robot interaction (HRI) is about understanding and shaping the interactions between humans and robots (Goodrich & Schultz, 2007). It is important to evaluate how the design of interfaces and command modalities affect the human s ability to perform tasks accurately, efficiently, and effectively (Crandall, Goodrich, Olsen Jr., & Nielsen, 2005) It is also critical to evaluate the effects of human-robot interfaces and command modalities on operator mental workload (Sheridan, 1992) and situation awareness (Endsley, Bolt , & Jones, 2003). By understanding the effects of interface design on human performance, workload, and situation awareness, interfaces can be developed that support the human in performing tasks with minimal errors and with appropriate interaction time and effort. Thus, the results of research on human-robot interfaces have direct implications for design. Because the factors associated with interfaces and command modalities in HRI are too numerous to address in 3 years of research, the proposed research concentrates on three manageable areas applicable to National Aeronautics and Space Administration (NASA) robot systems. These topic areas emerged from the Fiscal Year (FY) 2011 work that included extensive literature reviews and observations of NASA systems. The three topic areas are: 1) video overlays, 2) camera views, and 3) command modalities. Each area is described in detail below, along with relevance to existing NASA human-robot systems. In addition to studies in these three topic areas, a workshop is proposed for FY12. The workshop will bring together experts in human-robot interaction and robotics to discuss the state of the practice as applicable to research in space robotics. Studies proposed in the area of video overlays consider two factors in the implementation of augmented reality (AR) for operator displays during teleoperation. The first of these factors is the type of navigational guidance provided by AR symbology. In the proposed

  11. Experiences with project-oriented research in graduate engineering education

    International Nuclear Information System (INIS)

    Miley, G.H.

    1976-01-01

    Two examples of project-oriented research that involve the conceptual design of fusion systems are described. One of these projects involved close collaboration with workers in a national laboratory while the second was formally organized as a cooperative effort with two other laboratories. An important educational aspect of such research is that the students are involved in a design team composed of both students and professionals facing a realistic problem. In retrospect, it appears that both students and faculty profited from the experience. Several students have taken jobs in related areas, and additional research has resulted at the University from new insight gained during the projects

  12. IAU Project and Research Activity in Nepal

    Science.gov (United States)

    Gautam, Suman

    2015-08-01

    The second half of the twentieth century has witnessed a tremendous development in the field of astronomy and space exploration. The large telescope both on the land and in the orbit, using the whole range of the electromagnetic spectra from radio waves to gamma rays are extending their range of exploration, right to the edge of the observable universe, and making astounding discoveries in the process. Many large international telescope facilities and global plans are accessible to all astronomers throughout the world, providing an inexpensive entry to cutting- edge international research for developing countries.Nepal is a mountainous country it has a wide range of climatic and altitude variations which varies from an elevation of 200 meter to ≥ 4000 meter. The average temperature varies from ≥ 25 o C to ≤ 0 to 5oC. Because of these diverse weather and climatic variation there is the potential for the establishment of sophisticated observatory/ data centre and link with each other. So, the future possible opportunity of astronomy in Nepal will be discussed. Besides Education and Research activities conducted in Tribhuvan University, Nepal under the support of International Astronomical Union (IAU) will also be highlighted. The importance brought by those two workshops conducted on data simulation supported by IAU under TF1 will also be discussed which is believed to play a vital role for the promotion and development of astronomy and astrophysics in developing countries.

  13. Research project: "Promotion of optimum brain ageing"

    CERN Multimedia

    IT Department

    2009-01-01

    The Rehabilitation and Geriatrics Department of the Geneva University Hospitals (HUG) has signed a research protocol with CERN with a view to promoting better understanding of the mechanisms that trigger Alzheimer’s disease. Alzheimer’s disease is a form of dementia associated with memory loss, inability to make plans and spatial disorientation. With 24 million sufferers worldwide at present, a figure that is predicted to rise to 29 million by 2020, it represents a major challenge for the coming decades. Prevention is a key factor in slowing the alarming spread of this disease. Delaying the onset of the disease could reduce the total number of cases by 50%. Why CERN? CERN is an international research organisation with a workforce that is predominantly male (a section of the population that has been little studied so far) and has a high level of education. Moreover, its pensioners are easy to reach since the majority live in the Geneva area. The aim of the study is to ev...

  14. 2010 Tetrapyrroles, Chemistry & Biology of Gordon Research Conference

    Energy Technology Data Exchange (ETDEWEB)

    Angela Wilks

    2010-07-30

    The objective of the Chemistry & Biology of Tetrapyrroles Gordon Conference is to bring together researchers from diverse disciplines that otherwise would not interact. By bringing biologists, chemists, engineers and clinicians with a common interest in tetrapyrroles the conference provides a forum for cross-disciplinary ideas and collaboration. The perspective provided by biologists, chemists, and clinicians working in fields such as newly discovered defects in human porphyrin metabolism, the myriad of strategies for light harvesting in photosynthetic organisms, novel tetrapyrroles that serve as auxiliary chromophores or enzyme cofactors, synthetic strategies in the design of novel tetrapyrrole scaffolds, and tetrapyrrole based cell signaling and regulatory systems, makes this conference unique in the field. Over the years the growing evidence for the role of tetrapyrroles and their reactive intermediates in cell signaling and regulation has been of increasing importance at this conference. The 2010 conference on Chemistry & Biology of Tetrapyrroles will focus on many of these new frontiers as outlined in the preliminary program listed. Speakers will emphasize unpublished results and new findings in the field. The oral sessions will be followed by the highly interactive afternoon poster sessions. The poster sessions provide all conferees with the opportunity to present their latest research and to exchange ideas in a more informal setting. As in the past, this opportunity will continue during the nightly social gathering that takes place in the poster hall following the evening lectures. All conferees are encouraged to submit and present posters. At the conference the best poster in the areas of biology, chemistry and medicine will be selected by a panel of previous conference chairs.

  15. Energy research information system projects report, volume 5, number 1

    Science.gov (United States)

    Johnson, J.; Schillinger, L.

    1980-07-01

    The system (ERIS) provides an inventory of the energy related programs and research activities from 1974 to the present in the states of Montana, Nebraska, North Dakota, South Dakota and Wyoming. Areas of research covered include coal, reclamation, water resources, environmental impacts, socioeconomic impacts, energy conversion, mining methodology, petroleum, natural gas, oilshale, renewable energy resources, nuclear energy, energy conservation and land use. Each project description lists title, investigator(s), research institution, sponsor, funding, time frame, location, a descriptive abstract of the research and title reports and/or publications generated by the research. All projects are indexed by location, personal names, organizations and subject keywords.

  16. Methods of 15N tracer research in biological systems

    International Nuclear Information System (INIS)

    Hirschberg, K.; Faust, H.

    1985-01-01

    The application of the stable isotope 15 N is of increasing importance in different scientific disciplines, especially in medicine, agriculture, and the biosciences. The close correlation between the growing interest and improvements of analytical procedures resulted in remarkable advances in the 15 N tracer technique. On the basis of the latest results of 15 N tracer research in life sciences and agriculture methods of 15 N tracer research in biological systems are compiled. The 15 N methodology is considered under three headings: Chemical analysis with a description of methods of sample preparation (including different separation and isolation methods for N-containing substances of biological and agricultural origin) and special procedures converting ammonia to molecular nitrogen. Isotopic analysis with a review on the most important methods of isotopic analysis of nitrogen: mass spectrometry (including the GC-MS technique), emission spectrometry, NMR spectroscopy, and other analytical procedures. 15 N-tracer techniques with a consideration of the role of the isotope dilution analysis as well as different labelling techniques and the mathematical interpretation of tracer data (modelling, N turnover experiments). In these chapters also sources of errors in chemical and isotopic analysis, the accuracy of the different methods and its importance on tracer experiments are discussed. Procedures for micro scale 15 N analysis and aspects of 15 N analysis on the level of natural abundance are considered. Furthermore some remarks on isotope effects in 15 N tracer experiments are made. (author)

  17. The IT project manager competencies that impact project success – A qualitative research

    Directory of Open Access Journals (Sweden)

    Cíntia Cristina Silva de Araújo

    2015-07-01

    Full Text Available Since there is a lack of studies about the relationship of IT project manager competencies and project success, this paper will address the following research question: Which competencies should IT project managers develop in order to achieve success in IT projects? To answer this question, we conducted a qualitative research with an exploratory approach. To collect data, twelve (12 in-depth interviews were done with Brazilian project managers from different companies from several business sectors. The analysis results pointed out that for our respondents the most needed category of competencies are team management, business domain knowledge,  communication, project management and people skills. As other authors have affirmed, technical skills were considered to be less relevant to project success than interpersonal and intrapersonal competencies.

  18. Final Project Report Load Modeling Transmission Research

    Energy Technology Data Exchange (ETDEWEB)

    Lesieutre, Bernard [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bravo, Richard [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Yinger, Robert [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Chassin, Dave [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Huang, Henry [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lu, Ning [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hiskens, Ian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Venkataramanan, Giri [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-03-31

    The research presented in this report primarily focuses on improving power system load models to better represent their impact on system behavior. The previous standard load model fails to capture the delayed voltage recovery events that are observed in the Southwest and elsewhere. These events are attributed to stalled air conditioner units after a fault. To gain a better understanding of their role in these events and to guide modeling efforts, typical air conditioner units were testing in laboratories. Using data obtained from these extensive tests, new load models were developed to match air conditioner behavior. An air conditioner model is incorporated in the new WECC composite load model. These models are used in dynamic studies of the West and can impact power transfer limits for California. Unit-level and systemlevel solutions are proposed as potential solutions to the delayed voltage recovery problem.

  19. Valuing of research project in energy field with real options

    International Nuclear Information System (INIS)

    De Blasio, N.; Marzo, G.; Turatto, R.

    2008-01-01

    This article presents an application of real options theory for valuing a research project in the field of stranded gas valorisation. After a presentation of the theory, the analysis addresses the use of real options evaluation for generating alternative pathways in order to add new value to the R D projects. It also shows how real option approach may be important for selecting among competitive projects, but also for providing a system for valorisation of decision-maker flexibility [it

  20. The Research of Stakeholder Power Impact on Project Implementation

    Directory of Open Access Journals (Sweden)

    Artur Biskupek

    2016-12-01

    Full Text Available Purpose of the article: The article show summarized information about stakeholders and their role in project implementation based on literature review. The second part of the article is dedicated for the research about stakeholder influence on project implementation. The only condition to participate in the survey was managing projects. Although the respondents are employed in the area of south Poland, they implement projects all over Poland. The research tool was a questionnaire which was sent by e-mail to the respondents. 90 project managers from the area of south Poland were invited to join the project, and 62 people sent back a completed questionnaire. Methodology/methods: The research was done by a questionnaire with twenty two question, which was divided into three parts. The first part was the imprint, which consisted of three questions. The second part consisted of two questions, which concerned the way of defining the word “stakeholder”. The third part concerned the topic of the research and consisted of seventeen questions. Scientific aim: The aim of the article is presenting the results of the research which was done, to show the research results of project stakeholder influence on the project implementation. Findings: The results received from the survey in the process of analysis and interpretation allow to put forward a thesis that stakeholders as a whole group are significant for the implementation of the whole project. Their impact is so important that it is possible to tell that they decide also about the project success or failure. Conclusions: The respondents show that stakeholders affect every area in large extent or very big extent. The fact has been proved in table 1 which shows the most frequently chosen answers by responders. However, by conducted analysis by the standard deviation it is possible to see a large dispersion of the results.

  1. Water Resources Research Grant Program project descriptions, fiscal year 1987

    Science.gov (United States)

    ,

    1987-01-01

    This report contains information on the 34 new projects funded by the United States Geological Survey 's Water Resources Research Grant Program in fiscal year 1987 and on 3 projects completed during the year. For the new projects, the report gives the grant number, project title, performing organization, principal investigator(s), and a project description that includes: (1) identification of water related problems and problem-solution approach (2) contribution to problem solution, (3) objectives, and (4) approach. The 34 projects include 12 in the area of groundwater quality problems, 12 in the science and technology of water quality management, 1 in climate variability and the hydrologic cycle, 4 in institutional change in water resources management, and 5 in surface water management. For the three completed projects, the report furnishes the grant number; project title; performing organization; principal investor(s); starting data; data of receipt of final report; and an abstract of the final report. Each project description provides the information needed to obtain a copy of the final report. The report contains tables showing: (1) proposals received according to area of research interest, (2) grant awards and funding according to area of research interest, (3) proposals received according to type of submitting organization, and (4) awards and funding according to type of organization. (Author 's abstract)

  2. Community-researcher liaisons: the Pathways to Resilience Project ...

    African Journals Online (AJOL)

    The Pathways to Resilience Project is an ongoing, community-based participatory research (CBPR) project. Its express focus is the exploration of how at-risk youths use formal services and/or informal, naturally occurring resources to beat the odds that have been stacked against them, with the intent of partnering with ...

  3. Systems Engineering Applications for Small Business Innovative Research (SBIR) Projects

    Science.gov (United States)

    2012-09-01

    Engineering processes within the SBIR community. Information was collected from multiple organizations throughout the SBIR community to support this research...Force by Program Executive Officers, Technolgy Directorates, Air Logistics Centers and Test Centers. SBIR projects are developed in three phases...found to be associated with SBIR projects and varied among organizations. Thus it became essential to conduct interviews to gather the information

  4. Childhood Obesity Research Demonstration project: Cross-site evaluation method

    Science.gov (United States)

    The Childhood Obesity Research Demonstration (CORD) project links public health and primary care interventions in three projects described in detail in accompanying articles in this issue of Childhood Obesity. This article describes a comprehensive evaluation plan to determine the extent to which th...

  5. Research projects and capacity building | Breen | Water SA

    African Journals Online (AJOL)

    ... by capacity building in the context of research projects. Based on this interpretation, reasonable and unreasonable expectations with respect to the extent to which capacity building can be achieved within a given project duration are discussed. A model is suggested, which would improve understanding and delivery and ...

  6. An Applied Project-Driven Approach to Undergraduate Research Experiences

    Science.gov (United States)

    Karls, Michael A.

    2017-01-01

    In this paper I will outline the process I have developed for conducting applied mathematics research with undergraduates and give some examples of the projects we have worked on. Several of these projects have led to refereed publications that could be used to illustrate topics taught in the undergraduate curriculum.

  7. Using design science in educational technology research projects

    Directory of Open Access Journals (Sweden)

    Susan M. Chard

    2017-12-01

    Full Text Available Design science is a research paradigm where the development and evaluation of a technology artefact is a key contribution. Design science is used in many domains and this paper draws on those domains to formulate a generic structure for design science research suitable for educational technology research projects. The paper includes guidelines for writing proposals using the design science research methodology for educational technology research and presents a generic research report structure. The paper presents ethical issues to consider in design science research being conducted in educational settings and contributes guidelines for assessment when the research contribution involves the creation of a technology artefact.

  8. The Health Information Literacy Research Project*

    Science.gov (United States)

    Kurtz-Rossi, Sabrina; Funk, Carla J.

    2009-01-01

    Objectives: This research studied hospital administrators' and hospital-based health care providers' (collectively, the target group) perceived value of consumer health information resources and of librarians' roles in promoting health information literacy in their institutions. Methods: A web-based needs survey was developed and administered to hospital administrators and health care providers. Multiple health information literacy curricula were developed. One was pilot-tested by nine hospital libraries in the United States and Canada. Quantitative and qualitative methods were used to evaluate the curriculum and its impact on the target group. Results: A majority of survey respondents believed that providing consumer health information resources was critically important to fulfilling their institutions' missions and that their hospitals could improve health information literacy by increasing awareness of its impact on patient care and by training staff to become more knowledgeable about health literacy barriers. The study showed that a librarian-taught health information literacy curriculum did raise awareness about the issue among the target group and increased both the use of National Library of Medicine consumer health resources and referrals to librarians for health information literacy support. Conclusions: It is hoped that many hospital administrators and health care providers will take the health information literacy curricula and recognize that librarians can educate about the topic and that providers will use related consumer health services and resources. PMID:19851494

  9. Progress Report of the Schools Television Research Project--III

    Science.gov (United States)

    Kemelfield, Graeme

    1969-01-01

    "This concluding article provides the first published account of a series of psychological experiments which are presently being undertaken by the Schools Television Research Project, examining presentation factors in instructional television. (Editor)

  10. Tunnel Boring Machine for nuclear waste repository research project

    International Nuclear Information System (INIS)

    Janzon, H.A.

    1994-01-01

    A description is presented of a Tunnel Boring Machine and its intended use on a research project underway in Sweden for demonstrating and testing methods for rock investigation at a suitable depth for a deep repository for nuclear waste

  11. Evaluation of the Treatment of Diabetic Retinopathy A Research Project

    Science.gov (United States)

    Kupfer, Carl

    1973-01-01

    Evaluated is the treatment of diabetic retinopathy (blindness due to ruptured vessels of the retina as a side effect of diabetes), and described is a research project comparing two types of photocoagulation treatment. (DB)

  12. Advanced Research Projects Agency on Materials Preparation and Characterization Research

    Science.gov (United States)

    Briefly summarized is research concerned with such topics as: Preparation of silica glass from amorphous silica; Glass structure by Raman ...ferroelectrics; Silver iodide crystals; Vapor phase growth; Refractory optical host materials; Hydroxyapatite ; Calcite; Characterization of single crystals with a double crystal spectrometer; Characterization of residual strain.

  13. Division of Biological and Medical Research annual report, 1980

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1981-08-01

    The research during 1980 in the Division of Biological and Medical Research, Argonne National Laboratory, is summarized. Research related to nuclear energy includes the delineation, in the beagle, of the responses to continuous low level 60 Co gamma radiation and the development of cellular indicators of preclinical phases of leukemia; comparison of lifetime effects in mice of low level neutron and 60 Co gamma radiation; studies of the genetic effects of high LET radiations; and studies of the gastrointestinal absorption of the actinide elements. Research related to nonuclear energy sources deals with characterization and toxicological evaluation of process streams and effluents of coal gasification; with electrical storage systems; and electric fields associated with energy transmission. Proteins in human urine and selected tissues are examined by two-dimensional electrophoresis to detect disease and pollutant related changes. Assessment of human risk associated with nuclearing collective dose commitment will result in more attention being paid to potential releases of radionuclides at relatively short times after disposal

  14. Crowdfunding Campaigns Help Researchers Launch Projects and Generate Outreach.

    Science.gov (United States)

    Dahlhausen, Katherine; Krebs, Bethany L; Watters, Jason V; Ganz, Holly H

    2016-03-01

    Organizers of participatory research (citizen science) projects can generate funds and outreach through crowdfunding. Here we provide insights from three successful science crowdfunding campaigns recently completed on Indiegogo, Experiment, and Kickstarter. Choosing a crowdfunding platform that fits the project is just the beginning; a successful campaign reflects its content, management, and marketing, and some researchers may need to acquire new skills. In addition, the growing trend of crowdfunding for science reinforces the importance of academic engagement with social media.

  15. Crowdfunding Campaigns Help Researchers Launch Projects and Generate Outreach

    Directory of Open Access Journals (Sweden)

    Katherine Dahlhausen

    2015-11-01

    Full Text Available Organizers of participatory research (citizen science projects can generate funds and outreach through crowdfunding. Here we provide insights from three successful science crowdfunding campaigns recently completed on Indiegogo, Experiment, and Kickstarter. Choosing a crowdfunding platform that fits the project is just the beginning; a successful campaign reflects its content, management, and marketing, and some researchers may need to acquire new skills. In addition, the growing trend of crowdfunding for science reinforces the importance of academic engagement with social media.

  16. Radiological safety research for nuclear excavation projects - Interoceanic canal studies

    International Nuclear Information System (INIS)

    Klement, A.W. Jr.

    1969-01-01

    The general radiological problems encountered in nuclear cratering and nuclear excavation projects are discussed. Procedures for assessing radiological problems in such projects are outlined. Included in the discussions are source term, meteorology, fallout prediction and ecological factors. Continuing research requirements as well as pre- and post-excavation studies are important considerations. The procedures followed in the current interoceanic canal feasibility studies provide examples of radiological safety problems, current solutions and needed research. (author)

  17. Radiological safety research for nuclear excavation projects - Interoceanic canal studies

    Energy Technology Data Exchange (ETDEWEB)

    Klement, Jr, A W [U.S. Atomic Energy Commission, Las Vegas, NV (United States)

    1969-07-01

    The general radiological problems encountered in nuclear cratering and nuclear excavation projects are discussed. Procedures for assessing radiological problems in such projects are outlined. Included in the discussions are source term, meteorology, fallout prediction and ecological factors. Continuing research requirements as well as pre- and post-excavation studies are important considerations. The procedures followed in the current interoceanic canal feasibility studies provide examples of radiological safety problems, current solutions and needed research. (author)

  18. United States Crystalline Repository Project - key research areas

    International Nuclear Information System (INIS)

    Patera, E.S.

    1986-01-01

    The Crystalline Repository Project is responsible for siting the second high-level nuclear waste repository in crystalline rock for the US Department of Energy. A methodology is being developed to define data and information needs and a way to evaluate that information. The areas of research the Crystalline Repository Project is involved in include fluid flow in a fractured network, coupled thermal, chemical and flow processes and cooperation in other nations and OECD research programs

  19. The relation between project management education and newer streams in project management research

    DEFF Research Database (Denmark)

    Leimbach, Timo; Goodall, Julie Bladt

    2017-01-01

    In the last decades, research in project management (PM) has experienced significant new inputs from a range of new PM methodologies and critical research streams. As a consequence, members of the more critical streams have called for the education of project managers to advance from that of trai......In the last decades, research in project management (PM) has experienced significant new inputs from a range of new PM methodologies and critical research streams. As a consequence, members of the more critical streams have called for the education of project managers to advance from...... that of training technicians, to fostering reflective practitioners that are better equipped to handle the increasing complexity of the profession. This paper is based on a recently commenced re-search project titled "Rethinking Project Management Education – the Role of Universities" that is aimed at analysing...... how the development of PM research is reflected in the education of project managers. On the basis of a short overview of the state of the art of PM education research and practices, the possible challenges for the development of PM education are discussed, and, finding that there is a lack...

  20. Research capacity building integrated into PHIT projects: leveraging research and research funding to build national capacity.

    Science.gov (United States)

    Hedt-Gauthier, Bethany L; Chilengi, Roma; Jackson, Elizabeth; Michel, Cathy; Napua, Manuel; Odhiambo, Jackline; Bawah, Ayaga

    2017-12-21

    Inadequate research capacity impedes the development of evidence-based health programming in sub-Saharan Africa. However, funding for research capacity building (RCB) is often insufficient and restricted, limiting institutions' ability to address current RCB needs. The Doris Duke Charitable Foundation's African Health Initiative (AHI) funded Population Health Implementation and Training (PHIT) partnership projects in five African countries (Ghana, Mozambique, Rwanda, Tanzania and Zambia) to implement health systems strengthening initiatives inclusive of RCB. Using Cooke's framework for RCB, RCB activity leaders from each country reported on RCB priorities, activities, program metrics, ongoing challenges and solutions. These were synthesized by the authorship team, identifying common challenges and lessons learned. For most countries, each of the RCB domains from Cooke's framework was a high priority. In about half of the countries, domain specific activities happened prior to PHIT. During PHIT, specific RCB activities varied across countries. However, all five countries used AHI funding to improve research administrative support and infrastructure, implement research trainings and support mentorship activities and research dissemination. While outcomes data were not systematically collected, countries reported holding 54 research trainings, forming 56 mentor-mentee relationships, training 201 individuals and awarding 22 PhD and Masters-level scholarships. Over the 5 years, 116 manuscripts were developed. Of the 59 manuscripts published in peer-reviewed journals, 29 had national first authors and 18 had national senior authors. Trainees participated in 99 conferences and projects held 37 forums with policy makers to facilitate research translation into policy. All five PHIT projects strongly reported an increase in RCB activities and commended the Doris Duke Charitable Foundation for prioritizing RCB, funding RCB at adequate levels and time frames and for allowing

  1. Impact of Interdisciplinary Undergraduate Research in Mathematics and Biology on the Development of a New Course Integrating Five STEM Disciplines

    Science.gov (United States)

    Caudill, Lester; Hill, April; Hoke, Kathy; Lipan, Ovidiu

    2010-01-01

    Funded by innovative programs at the National Science Foundation and the Howard Hughes Medical Institute, University of Richmond faculty in biology, chemistry, mathematics, physics, and computer science teamed up to offer first- and second-year students the opportunity to contribute to vibrant, interdisciplinary research projects. The result was…

  2. A Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm

    Energy Technology Data Exchange (ETDEWEB)

    Aderem, Alan; Adkins, Joshua N.; Ansong, Charles; Galagan, James; Kaiser, Shari; Korth, Marcus J.; Law, G. L.; McDermott, Jason E.; Proll, Sean; Rosenberger, Carrie; Schoolnik, Gary; Katze, Michael G.

    2011-02-01

    The 20th century was marked by extraordinary advances in our understanding of microbes and infectious disease, but pandemics remain, food and water borne illnesses are frequent, multi-drug resistant microbes are on the rise, and the needed drugs and vaccines have not been developed. The scientific approaches of the past—including the intense focus on individual genes and proteins typical of molecular biology—have not been sufficient to address these challenges. The first decade of the 21st century has seen remarkable innovations in technology and computational methods. These new tools provide nearly comprehensive views of complex biological systems and can provide a correspondingly deeper understanding of pathogen-host interactions. To take full advantage of these innovations, the National Institute of Allergy and Infectious Diseases recently initiated the Systems Biology Program for Infectious Disease Research. As participants of the Systems Biology Program we think that the time is at hand to redefine the pathogen-host research paradigm.

  3. 7 CFR 932.45 - Production research and marketing research and development projects.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Production research and marketing research and....45 Production research and marketing research and development projects. (a) The following activities... Secretary, establish or provide for the establishment of production research, and marketing research and...

  4. Human-Robot Interaction Directed Research Project

    Science.gov (United States)

    Sandor, Aniko; Cross, Ernest V., II; Chang, Mai Lee

    2014-01-01

    Human-robot interaction (HRI) is a discipline investigating the factors affecting the interactions between humans and robots. It is important to evaluate how the design of interfaces and command modalities affect the human's ability to perform tasks accurately, efficiently, and effectively when working with a robot. By understanding the effects of interface design on human performance, workload, and situation awareness, interfaces can be developed to appropriately support the human in performing tasks with minimal errors and with appropriate interaction time and effort. Thus, the results of research on human-robot interfaces have direct implications for the design of robotic systems. This DRP concentrates on three areas associated with interfaces and command modalities in HRI which are applicable to NASA robot systems: 1) Video Overlays, 2) Camera Views, and 3) Command Modalities. The first study focused on video overlays that investigated how Augmented Reality (AR) symbology can be added to the human-robot interface to improve teleoperation performance. Three types of AR symbology were explored in this study, command guidance (CG), situation guidance (SG), and both (SCG). CG symbology gives operators explicit instructions on what commands to input, whereas SG symbology gives operators implicit cues so that operators can infer the input commands. The combination of CG and SG provided operators with explicit and implicit cues allowing the operator to choose which symbology to utilize. The objective of the study was to understand how AR symbology affects the human operator's ability to align a robot arm to a target using a flight stick and the ability to allocate attention between the symbology and external views of the world. The study evaluated the effects type of symbology (CG and SG) has on operator tasks performance and attention allocation during teleoperation of a robot arm. The second study expanded on the first study by evaluating the effects of the type of

  5. Using Social Media for Research Dissemination: The Digital Research Video Project

    Directory of Open Access Journals (Sweden)

    Suzanne Pilaar Birch

    2013-09-01

    Full Text Available This article discusses the outcomes of the Digital Research Video Project, which was part of the larger Social Media Knowledge Exchange program at the Centre for Research in the Arts, Social Sciences, and Humanities (CRASSH at the University of Cambridge and funded by the Arts & Humanities Research Council (UK. The project was founded on the premise that open access publication of research, while important, does not necessarily make research accessible. Often, PhD students and post-doctoral scholars lack the skills needed to communicate their research to a broader audience. The goal of the project was, first, to provide communication training to early career researchers (achieved through a workshop held in autumn 2012 and second, to create illustrated videos highlighting projects by early career researchers that would help them engage with their work using multimedia and share their results with a larger audience. This article considers the methods of dissemination and impact of the project.

  6. Advances, gaps, and future prospects in biological soil crust research

    Science.gov (United States)

    Weber, Bettina; Büdel, Burkhard; Belnap, Jayne

    2017-04-01

    Research progress has led to the understanding that biological soil crusts (biocrusts) are often complete miniature ecosystems comprising a variety of photosynthesizers (cyanobacteria, algae, lichens, bryophytes), decomposers like bacteria, fungi, and archaea, and heterotrophic organisms, like protozoa, nematodes, and microarthropods feeding on them. Biocrusts are one of the oldest terrestrial ecosystems, playing central roles in the structure and functioning of dryland ecosystems and presumably also influencing global biogeochemical cycles. On the other hand, biocrusts have been shown to be highly sensitive to global change, being easily destroyed by mechanical disturbance and severely threatened by minor changes in climate patterns. Despite the large increase in biocrust research, we still see major knowledge gaps which need to be tackled. Considering biodiversity studies, there are major regions of potential biocrust occurrence, where hardly any studies have been conducted. Molecular identification techniques are increasingly employed, but genetically characterized entities need to be linked with morphologically identified organisms to identify their ecological roles. Although there is a large body of research on the role of biocrusts in water and nutrient budgets, we are still far from closing the overall cycles. Results suggest that not all mechanisms have been identified, yet, leading to sometimes contradictory results between different studies. Knowledge on how to minimize impact to biocrusts during surface-disturbing activities has hardly been gained, and despite research efforts, instructions on effective biocrust restoration are still exemplary. In order to fill these research gaps, novel scientific approaches are needed. We expect that global research networks could be extremely helpful to answer scientific questions by tackling them within different regions, utilizing the same methodological techniques. Global networks could also be used for long

  7. Needs assessment in health research projects: a new approach to project management in iran.

    Science.gov (United States)

    Peykari, Niloofar; Owlia, Parviz; Malekafzali, Hossein; Ghanei, Mostafa; Babamahmoodi, Abdolreza; Djalalinia, Shirin

    2013-01-01

    The science and technology health plan has defined the outline of health research to the national vision of Iran by 2025. The aim of this study was to focus on the process of needs assessment of health research projects also health research priority setting in Iran. THE PROJECT MANAGEMENT LIFE CYCLE HAS FOUR PHASES: Initiation, Planning, Execution and Closure. Based on abovementioned points we conducted the study. Focusing on the needs assessment led to systematic implementation of needs assessment of health project in all of the medical sciences universities. Parallel with this achieved strategies health research priority setting was followed through specific process from empowerment to implementation. We should adopt with more systematic progressive methods of health project managements for both our national convenience as well as our international health research programs.

  8. Life lines: An art history of biological research around 1800.

    Science.gov (United States)

    Bruhn, Matthias

    2011-12-01

    Around 1800, the scientific "illustrator" emerged as a new artistic profession in Europe. Artists were increasingly sought after in order to picture anatomical dissections and microscopic observations and to translate drawings into artworks for books and journals. By training and technical expertise, they introduced a particular kind of knowledge into scientific perception that also shaped the common image of nature. Illustrations of scientific publications, often undervalued as a biased interpretation of facts and subordinate to logic and description, thus convey an 'art history' of science in its own right, relevant both for the understanding of biological thought around 1800 as well as for the development of the arts and their historiography. The article is based on an analysis of botanical treatises produced for the Göttingen Society of Sciences in 1803, during an early phase of microscopic cell research, in order to determine the constitutive role of artistic knowledge and the media employed for the visualization and conceptualization of biological issues. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Growth Analysis of Cancer Biology Research, 2000-2011

    Directory of Open Access Journals (Sweden)

    Keshava,

    2015-09-01

    Full Text Available Methods and Material: The PubMed database was used for retrieving data on 'cancer biology.' Articles were downloaded from the years 2000 to 2011. The articles were classified chronologically and transferred to a spreadsheet application for analysis of the data as per the objectives of the study. Statistical Method: To investigate the nature of growth of articles via exponential, linear, and logistics tests. Result: The year wise analysis of the growth of articles output shows that for the years 2000 to 2005 and later there is a sudden increase in output, during the years 2006 to 2007 and 2008 to 2011. The high productivity of articles during these years may be due to their significance in cancer biology literature, having received prominence in research. Conclusion: There is an obvious need for better compilations of statistics on numbers of publications in the years from 2000 to 2011 on various disciplines on a worldwide scale, for informed critical assessments of the amount of new knowledge contributed by these publications, and for enhancements and refinements of present Scientometric techniques (citation and publication counts, so that valid measures of knowledge growth may be obtained. Only then will Scientometrics be able to provide accurate, useful descriptions and predictions of knowledge growth.

  10. Focusing Information Systems Post-Graduate Research Projects

    Directory of Open Access Journals (Sweden)

    Gail Ridley

    1996-11-01

    Full Text Available This paper reports on an investigation of mechanisms that assist Information Systems post-graduate research students to focus their projects. An evaluation is presented of the experiences of Information Systems research students in focussing their research projects based on a survey conducted of students who participated in two of the first three Information Systems doctoral consortia to be held in Australia. The survey sought to determine whether a doctoral consortium or 'systematic expert review' is the most valuable mechanism for focussing a research proposal. Systematic expert review was considered by the students to be more effective than the doctoral consortium process for the purpose of focussing their research project proposals.

  11. How the confocal laser scanning microscope entered biological research.

    Science.gov (United States)

    Amos, W B; White, J G

    2003-09-01

    A history of the early development of the confocal laser scanning microscope in the MRC Laboratory of Molecular Biology in Cambridge is presented. The rapid uptake of this technology is explained by the wide use of fluorescence in the 80s. The key innovations were the scanning of the light beam over the specimen rather than vice-versa and a high magnification at the level of the detector, allowing the use of a macroscopic iris. These were followed by an achromatic all-reflective relay system, a non-confocal transmission detector and novel software for control and basic image processing. This design was commercialized successfully and has been produced and developed over 17 years, surviving challenges from alternative technologies, including solid-state scanning systems. Lessons are pointed out from the unusual nature of the original funding and research environment. Attention is drawn to the slow adoption of the instrument in diagnostic medicine, despite promising applications.

  12. Data base on nuclear power plant dose reduction research projects

    Energy Technology Data Exchange (ETDEWEB)

    Khan, T.A.; Dionne, B.J.; Baum, J.W.

    1985-12-01

    This report contains project information on the research and development activities of the nuclear power industry in the area of dose reduction. It is based on a data base of information set up at the ALARA Center of Brookhaven National Laboratory. One purpose of this report is to draw attention to work in progress and to enable researchers and subscribers to obtain further information from the investigators and project managers. Information is provided on 180 projects, divided according to whether they are oriented to Engineering Research or to Health Physics Technology. The report contains indices on main category, project manager, principal investigator, sponsoring organization, contracting organization, and subject. This is an initial report. It is intended that periodic updates be issued whenever sufficient material has been accumulated.

  13. Data base on nuclear power plant dose reduction research projects

    International Nuclear Information System (INIS)

    Khan, T.A.; Dionne, B.J.; Baum, J.W.

    1985-12-01

    This report contains project information on the research and development activities of the nuclear power industry in the area of dose reduction. It is based on a data base of information set up at the ALARA Center of Brookhaven National Laboratory. One purpose of this report is to draw attention to work in progress and to enable researchers and subscribers to obtain further information from the investigators and project managers. Information is provided on 180 projects, divided according to whether they are oriented to Engineering Research or to Health Physics Technology. The report contains indices on main category, project manager, principal investigator, sponsoring organization, contracting organization, and subject. This is an initial report. It is intended that periodic updates be issued whenever sufficient material has been accumulated

  14. Research project management 101: insiders' tips from Early Career Scientists

    Science.gov (United States)

    Cristini, Luisa; Pabortsava, Katsiaryna; Stichel, Torben

    2016-04-01

    From the very beginning of their career, it is important for Early Career Scientists (ECS) to develop project management skills to be able to organise their research efficiently. ECS are often in charge of specific tasks within their projects or for their teams. However, without specific training or tools, the successful completion of these assignments will depend entirely on the organisational skills of individual researchers. ECS are thus facing "sink-or-swim" situations, which can be either instructive or disastrous for their projects. Here we provide experience-based tips from fellow ECS that can help manage various project activities, including: 1. Communication with supervisors and peers 2. Lab management 3. Field trips (e.g., oceanographic campaigns) 4. Internships and collaborations with other institutions 5. Literature/background research 6. Conference convening These are potential "life buoys" for ECS, which will help them to carry out these tasks efficiently and successfully.

  15. Reading Research Utilization Project: An RIC Project for Teachers and Other Field Personnel.

    Science.gov (United States)

    District of Columbia Public Schools, Washington, DC. Dept. of Research and Evaluation.

    This is the final report of the Reading Research Utilization Project (RUP) which was funded by the U.S. Office of Education from July, 1971 to June, 1973. The purpose of the RUP was to encourage the translation of research, particularly reading research, into practice in 16 target elementary schools in Washington, D.C. RUP was a school information…

  16. Microgravity research in plant biological systems: Realizing the potential of molecular biology

    Science.gov (United States)

    Lewis, Norman G.; Ryan, Clarence A.

    1993-01-01

    The sole all-pervasive feature of the environment that has helped shape, through evolution, all life on Earth is gravity. The near weightlessness of the Space Station Freedom space environment allows gravitational effects to be essentially uncoupled, thus providing an unprecedented opportunity to manipulate, systematically dissect, study, and exploit the role of gravity in the growth and development of all life forms. New and exciting opportunities are now available to utilize molecular biological and biochemical approaches to study the effects of microgravity on living organisms. By careful experimentation, we can determine how gravity perception occurs, how the resulting signals are produced and transduced, and how or if tissue-specific differences in gene expression occur. Microgravity research can provide unique new approaches to further our basic understanding of development and metabolic processes of cells and organisms, and to further the application of this new knowledge for the betterment of humankind.

  17. STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)

    International Nuclear Information System (INIS)

    Eisenberg, David S.

    2008-01-01

    The UCLA-DOE Institute of Genomics and Proteomics is an organized research unit of the University of California, sponsored by the Department of Energy through the mechanism of a Cooperative Agreement. Today the Institute consists of 10 Principal Investigators and 7 Associate Members, developing and applying technologies to promote the biological and environmental missions of the Department of Energy, and 5 Core Technology Centers to sustain this work. The focus is on understanding genomes, pathways and molecular machines in organisms of interest to DOE, with special emphasis on developing enabling technologies. Since it was founded in 1947, the UCLA-DOE Institute has adapted its mission to the research needs of DOE and its progenitor agencies as these research needs have changed. The Institute started as the AEC Laboratory of Nuclear Medicine, directed by Stafford Warren, who later became the founding Dean of the UCLA School of Medicine. In this sense, the entire UCLA medical center grew out of the precursor of our Institute. In 1963, the mission of the Institute was expanded into environmental studies by Director Ray Lunt. I became the third director in 1993, and in close consultation with David Galas and John Wooley of DOE, shifted the mission of the Institute towards genomics and proteomics. Since 1993, the Principal Investigators and Core Technology Centers are entirely new, and the Institute has separated from its former division concerned with PET imaging. The UCLA-DOE Institute shares the space of Boyer Hall with the Molecular Biology Institute, and assumes responsibility for the operation of the main core facilities. Fig. 1 gives the organizational chart of the Institute. Some of the benefits to the public of research carried out at the UCLA-DOE Institute include the following: The development of publicly accessible, web-based databases, including the Database of Protein Interactions, and the ProLinks database of genomicly inferred protein function linkages

  18. Laboratory Technology Research: Abstracts of FY 1996 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program are conducted by the five ER multi-program laboratories: Argonne, Brookhaven, Lawrence Berkeley, Oak Ridge, and Pacific Northwest National Laboratories. These projects explore the applications of basic research advances relevant to Department of Energy`s (DOE) mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing/manufacturing research, and sustainable environments.

  19. Laboratory technology research: Abstracts of FY 1998 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of the country: the world-class basic research capability of the DOE Office of Science (SC) national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program in FY 1998 explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing and manufacturing research, and environmental and biomedical research. Abstracts for 85 projects are contained in this report.

  20. Biological samples positioning device for irradiations on a radial channel at the nuclear research reactor

    International Nuclear Information System (INIS)

    Rodriguez Gual, Maritza; Mas Milian, Felix; Deppman, Airton; Pinto Coelho, Paulo Rogerio

    2010-01-01

    For the demand of an experimental device for biological samples positioning system for irradiations on a radial channel at the nuclear research reactor in operation was constructed and started up a device for the place and remove of the biological samples from the irradiation channels without interrupting the operation of the reactor. The economical valuations are effected comparing with another type of device with the same functions. This work formed part of an international project between Cuba and Brazil that undertook the study of the induced damages by various types of ionizing radiation in DNA molecules. Was experimentally tested the proposed solution, which demonstrates the practical validity of the device. As a result of the work, the experimental device for biological samples irradiations are installed and operating in the radial beam hole No3(BH3) for more than five years at the IEA-R1 Brazilian research reactor according to the solicited requirements the device. The designed device increases considerably the type of studies can be conducted in this reactor. Its practical application in research taking place in that facility, in the field of radiobiology and dosimetry, and so on is immediate

  1. Multiweek Cell Culture Project for Use in Upper-Level Biology Laboratories

    Science.gov (United States)

    Marion, Rebecca E.; Gardner, Grant E.; Parks, Lisa D.

    2012-01-01

    This article describes a laboratory protocol for a multiweek project piloted in a new upper-level biology laboratory (BIO 426) using cell culture techniques. Human embryonic kidney-293 cells were used, and several culture media and supplements were identified for students to design their own experiments. Treatments included amino acids, EGF,…

  2. Two Project-Based Strategies in an Interdisciplinary Mathematical Modeling in Biology Course

    Science.gov (United States)

    Ludwig, Patrice; Tongen, Anthony; Walton, Brian

    2018-01-01

    James Madison University faculty team-teach an interdisciplinary mathematical modeling course for mathematics and biology students. We have used two different project-based approaches to emphasize the mathematical concepts taught in class, while also exposing students to new areas of mathematics not formally covered in class. The first method…

  3. Which Type of Inquiry Project Do High School Biology Students Prefer: Open or Guided?

    Science.gov (United States)

    Sadeh, Irit; Zion, Michal

    2012-01-01

    In teaching inquiry to high school students, educators differ on which method of teaching inquiry is more effective: Guided or open inquiry? This paper examines the influence of these two different inquiry learning approaches on the attitudes of Israeli high school biology students toward their inquiry project. The results showed significant…

  4. The Maine Garlic Project: A Participatory Research and Education Program

    Science.gov (United States)

    Fuller, David; Johnson, Steven B.

    2013-01-01

    Participatory research is a useful technique for collecting basic data over a large geographic area. Garlic production was chosen as a participatory research study focus in Maine. Project participants (285) received bulbs to plant, monitored their crop, and reported data online. Participants received a monthly educational newsletter to improve…

  5. Pacific Lamprey Research and Restoration Project : Annual Report 2000.

    Energy Technology Data Exchange (ETDEWEB)

    Close, David A.

    2002-11-01

    This report summarizes results of research activities conducted in 1999-2000. The findings in these chapters represent the efforts of the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) and collaborative efforts among other researchers working on Pacific lampreys (Lampetra tridentata) under this project. The findings in these chapters will help management and recovery of Pacific lampreys in the Columbia River Basin.

  6. 38 CFR 21.390 - Rehabilitation research and special projects.

    Science.gov (United States)

    2010-07-01

    ... Employment Under 38 U.S.C. Chapter 31 Rehabilitation Research and Special Projects § 21.390 Rehabilitation... purpose of advancing the knowledge, methods, techniques, and resources available for use in rehabilitation...(b)) (c) Research by Vocational Rehabilitation and Employment (VR&E) staff members. VA will encourage...

  7. THE CONTRIBUTION OF RESEARCH INSTITUTES IN EUREKA PROJECTS

    NARCIS (Netherlands)

    VANROSSUM, W; CABO, PG

    1995-01-01

    Technological cooperation between industrial firms and research institutes is studied at the project level. The various forms of cooperation, and the instances in which they are advantageous, are discussed. The authors then focus on situations in which the research institute acts as 'knowledge

  8. Impact of externally funded projects on development of research ...

    African Journals Online (AJOL)

    Impact of externally funded projects on development of research capability of national agricultural research system. S K Sharma. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL.

  9. Student Perceptions on Live-Case Projects: Undergraduate Marketing Research

    Science.gov (United States)

    Gundala, Raghava Rao; Singh, Mandeep; Baldwin, Andrew

    2014-01-01

    This paper is an investigation into undergraduate students' perceptions on use of live projects as a teaching pedagogy in marketing research courses. Students in undergraduate marketing research courses from fall 2009 to spring 2013 completed an online questionnaire consisting of 17 items. The results suggested that student understanding of…

  10. New York State Energy Research and Development Authority. Research projects` update project status as of March 31, 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    This report provides an update of the New York State Energy Research and Development Authority (NYSERDA) program. The NYSERDA research and development program has five major areas: industry, buildings, energy resources, transportation, and environment. NYSERDA organizes projects within these five major areas based on energy use and supply, and end-use sectors. Therefore, issues such as waste management, energy products and renewable energy technologies are addressed in several areas of the program. The project descriptions presented are organized within the five program areas. Descriptions of projects completed between the period April 1, 1996, and March 31, 1997, including technology-transfer activities, are at the end of each subprogram section.

  11. Impact of Interdisciplinary Undergraduate Research in mathematics and biology on the development of a new course integrating five STEM disciplines.

    Science.gov (United States)

    Caudill, Lester; Hill, April; Hoke, Kathy; Lipan, Ovidiu

    2010-01-01

    Funded by innovative programs at the National Science Foundation and the Howard Hughes Medical Institute, University of Richmond faculty in biology, chemistry, mathematics, physics, and computer science teamed up to offer first- and second-year students the opportunity to contribute to vibrant, interdisciplinary research projects. The result was not only good science but also good science that motivated and informed course development. Here, we describe four recent undergraduate research projects involving students and faculty in biology, physics, mathematics, and computer science and how each contributed in significant ways to the conception and implementation of our new Integrated Quantitative Science course, a course for first-year students that integrates the material in the first course of the major in each of biology, chemistry, mathematics, computer science, and physics.

  12. Cell Science and Cell Biology Research at MSFC: Summary

    Science.gov (United States)

    2003-01-01

    The common theme of these research programs is that they investigate regulation of gene expression in cells, and ultimately gene expression is controlled by the macromolecular interactions between regulatory proteins and DNA. The NASA Critical Path Roadmap identifies Muscle Alterations and Atrophy and Radiation Effects as Very Serious Risks and Severe Risks, respectively, in long term space flights. The specific problem addressed by Dr. Young's research ("Skeletal Muscle Atrophy and Muscle Cell Signaling") is that skeletal muscle loss in space cannot be prevented by vigorous exercise. Aerobic skeletal muscles (i.e., red muscles) undergo the most extensive atrophy during long-term space flight. Of the many different potential avenues for preventing muscle atrophy, Dr. Young has chosen to study the beta-adrenergic receptor (betaAR) pathway. The reason for this choice is that a family of compounds called betaAR agonists will preferentially cause an increase in muscle mass of aerobic muscles (i.e., red muscle) in animals, potentially providing a specific pharmacological solution to muscle loss in microgravity. In addition, muscle atrophy is a widespread medical problem in neuromuscular diseases, spinal cord injury, lack of exercise, aging, and any disease requiring prolonged bedridden status. Skeletal muscle cells in cell culture are utilized as a model system to study this problem. Dr. Richmond's research ("Radiation & Cancer Biology of Mammary Cells in Culture") is directed toward developing a laboratory model for use in risk assessment of cancer caused by space radiation. This research is unique because a human model will be developed utilizing human mammary cells that are highly susceptible to tumor development. This approach is preferential over using animal cells because of problems in comparing radiation-induced cancers between humans and animals.

  13. The Implementation of Research-based Learning on Biology Seminar Course in Biology Education Study Program of FKIP UMRAH

    Science.gov (United States)

    Amelia, T.

    2018-04-01

    Biology Seminar is a course in Biology Education Study Program of Faculty of Teacher Training and Education University of Maritim Raja Ali Haji (FKIP UMRAH) that requires students to have the ability to apply scientific attitudes, perform scientific writing and undertake scientific publications on a small scale. One of the learning strategies that can drive the achievement of learning outcomes in this course is Research-Based Learning. Research-Based Learning principles are considered in accordance with learning outcomes in Biology Seminar courses and generally in accordance with the purpose of higher education. On this basis, this article which is derived from a qualitative research aims at describing Research-based Learning on Biology Seminar course. Based on a case study research, it was known that Research-Based Learning on Biology Seminar courses is applied through: designing learning activities around contemporary research issues; teaching research methods, techniques and skills explicitly within program; drawing on personal research in designing and teaching courses; building small-scale research activities into undergraduate assignment; and infusing teaching with the values of researchers.

  14. Fiscal 1993 technological survey report. R and D project for industrial science and technology (Assignment by NEDO/R and D of biochip - survey on biological research of biochip); 1993 nendo bio soshi no kenkyu kaihatsu seika hokokusho. Bio soshi seibutsu kenkyu chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-04-01

    As a part of the R and D of a biochip, for the purpose of establishing fundamental technology in connection with a biochip having a new function that is nonexistent in a semiconductor, a committee for biological research and survey of biochip was organized, operating research activities, surveying and compiling research situations and technological trend at the forefront of each field, in regard to information processing in the biological field, brain-memory related information processing in the medical field, and biologically simulated information processing in the engineering field. The results were summarized in the following seven areas. 1. neurology of memory, 2. the frontal lobe and recognition, 3. function of the olfactory lobe and neural connection between the olfactory lobe and the hippocampus, 4. the cerebral fundus nucleus and function, 5. coordinate change from vision to motion in the brain, and 6. control of transient potassium current by the astroglia cell in the mouth and the hippocampus cultured nerve cell. (NEDO)

  15. Soil protists: a fertile frontier in soil biology research.

    Science.gov (United States)

    Geisen, Stefan; Mitchell, Edward A D; Adl, Sina; Bonkowski, Michael; Dunthorn, Micah; Ekelund, Flemming; Fernández, Leonardo D; Jousset, Alexandre; Krashevska, Valentyna; Singer, David; Spiegel, Frederick W; Walochnik, Julia; Lara, Enrique

    2018-05-01

    Protists include all eukaryotes except plants, fungi and animals. They are an essential, yet often forgotten, component of the soil microbiome. Method developments have now furthered our understanding of the real taxonomic and functional diversity of soil protists. They occupy key roles in microbial foodwebs as consumers of bacteria, fungi and other small eukaryotes. As parasites of plants, animals and even of larger protists, they regulate populations and shape communities. Pathogenic forms play a major role in public health issues as human parasites, or act as agricultural pests. Predatory soil protists release nutrients enhancing plant growth. Soil protists are of key importance for our understanding of eukaryotic evolution and microbial biogeography. Soil protists are also useful in applied research as bioindicators of soil quality, as models in ecotoxicology and as potential biofertilizers and biocontrol agents. In this review, we provide an overview of the enormous morphological, taxonomical and functional diversity of soil protists, and discuss current challenges and opportunities in soil protistology. Research in soil biology would clearly benefit from incorporating more protistology alongside the study of bacteria, fungi and animals.

  16. Research from Afar: Considerations for Conducting an Off-Site Research Project.

    Science.gov (United States)

    Williams, Reg Arthur; Hagerty, Bonnie M.; Hoyle, Kenneth; Yousha, Steven M.; Abdoo, Yvonne; Andersen, Curt; Engler, Dorothy

    1999-01-01

    Critical elements in the success of off-site research projects include the following: negotiation, attention to personnel issues, communication, participation of research subjects, data management, and concern for privacy issues. (SK)

  17. Evolution of project management research: a bibliometric study of International Journal of Project Management

    Directory of Open Access Journals (Sweden)

    Fábio Cocchi da Silva Eiras

    2017-03-01

    Full Text Available Over the past decades, the project management field has evolved and consolidated. Facing this growth, this research aims to identify the main trends of research in the area, as well as providing an overview of publications, identifying new issues, changes in approaches and the development of knowledge areas. To do so, a systematic review of the literature was performed with the use of bibliometric study in the papers of the International Journal of Project Management (IJPM, included in SCOPUS, from its first volume to 2015, covering a period of more than 30 years. It was found that developing countries are increasingly concerned in developing research into the field of project management, especially in mega infrastructure projects and public-private partnerships. The risk is a central topic in all periods of analysis, however, the strategic topics such as success in project and portfolio management are among the fastest growing. Issues related to the soft side of project management as skills, culture, and knowledge management have emerged in recent periods. According to the industry, construction projects and projects in information technology are the most studied along the period analysed.

  18. Roles of radiation chemistry in development and research of radiation biology

    International Nuclear Information System (INIS)

    Min Rui

    2009-01-01

    Radiation chemistry acts as a bridge connecting radiation physics with radiation biology in spatial and temporal insight. The theory, model, and methodology coming from radiation chemistry play an important role in the research and development of radiation biology. The chemical changes induced by ionizing radiation are involved not only in early event of biological effects caused by ionizing radiation but in function radiation biology, such as DNA damage and repair, sensitive modification, metabolism and function of active oxygen and so on. Following the research development of radiation biology, systems radiation biology, accurate quality and quantity of radiation biology effects need more methods and perfect tools from radiation chemistry. (authors)

  19. Using biological control research in the classroom to promote scientific inquiry and literacy

    Science.gov (United States)

    Many scientists who research biological control also teach at universities or more informally through cooperative outreach. The purpose of this paper is to review biological control activities for the classroom in four refereed journals, The American Biology Teacher, Journal of Biological Education...

  20. Research on reconstruction of steel tube section from few projections

    International Nuclear Information System (INIS)

    Peng Shuaijun; Wu Haifeng; Wang Kai

    2007-01-01

    Most parameters of steel tube can be acquired from CT image of the section so as to evaluate its quality. But large numbers of projections are needed in order to reconstruct the section image, so the collection and calculation of the projections consume lots of time. In order to solve the problem, reconstruction algorithms of steel tube from few projections are researched and the results are validated with simulation data in the paper. Three iterative algorithms, ART, MAP and OSEM, are attempted to reconstruct the section of steel tube by using the simulation model. Considering the prior information distributing of steel tube, we improve the algorithms and get better reconstruction images. The results of simulation experiment indicate that ART, MAP and OSEM can reconstruct accurate section images of steel tube from less than 20 projections and approximate images from 10 projections. (authors)

  1. Impact of Interdisciplinary Undergraduate Research in Mathematics and Biology on the Development of a New Course Integrating Five STEM Disciplines

    OpenAIRE

    Caudill, Lester; Hill, April; Hoke, Kathy; Lipan, Ovidiu

    2010-01-01

    Funded by innovative programs at the National Science Foundation and the Howard Hughes Medical Institute, University of Richmond faculty in biology, chemistry, mathematics, physics, and computer science teamed up to offer first- and second-year students the opportunity to contribute to vibrant, interdisciplinary research projects. The result was not only good science but also good science that motivated and informed course development. Here, we describe four recent undergraduate research proj...

  2. CARONTE project: Creating an Agenda for Research on Transportation Security

    Energy Technology Data Exchange (ETDEWEB)

    Leon Bello, J.; Gonzalez Viosca, E.

    2016-07-01

    Europe’s prosperity relies on effective transport systems. Any attacks and disturbances to land freight and passenger transport would have significant impact on economic growth, territorial cohesion, social development and the environment. Unfortunately, there are weaknesses in the land transport security.The objective of CARONTE project is define a future research agenda for security in land transport that focuses on core gaps caused by emerging risks while avoiding any doubling-up of research elsewhere. Its research agenda will cover all threats, including cyber-crime, and security aspects across all modes of land transportation. At the same time, it will respect the fundamental human rights and privacy of European citizens. The step-by-step method of CARONTE’s consortium has analyzed the state of the art and emerging risks; has identified gaps, analyses and assessments of potential solutions; and has produced an overall research agenda for the future. CARONTE’s results will answer the following questions among others: Which existing research projects merit a follow up and extension? Where are the combinations or synergy effects to be attended? Which themes and topics should be elaborated in new research projects? Who should be involved and integrated in future research projects (stakeholders, authorities, etc.)? The CARONTE consortium includes universities and research institutes, companies, and end-users providing with experience in research and consultancy in transportation, logistics, infrastructure management, security and communications. ITENE - Instituto Tecnológico del Embalaje, Transporte y Logística-has been one of the Project partners among a total of 11 members from eight different countries in the European Union which have also been supported via a High Level Advisory Board. (Author)

  3. Tritium research laboratory cleanup and transition project final report

    International Nuclear Information System (INIS)

    Johnson, A.J.

    1997-02-01

    This Tritium Research Laboratory Cleanup and Transition Project Final Report provides a high-level summary of this project's multidimensional accomplishments. Throughout this report references are provided for in-depth information concerning the various topical areas. Project related records also offer solutions to many of the technical and or administrative challenges that such a cleanup effort requires. These documents and the experience obtained during this effort are valuable resources to the DOE, which has more than 1200 other process contaminated facilities awaiting cleanup and reapplication or demolition

  4. Dryden Flight Research Center Critical Chain Project Management Implementation

    Science.gov (United States)

    Hines, Dennis O.

    2012-01-01

    In Fiscal Year 2011 Dryden Flight Research Center (DFRC) implemented a new project management system called Critical Chain Project Management (CCPM). Recent NASA audits have found that the Dryden workforce is strained under increasing project demand and that multi-tasking has been carried to a whole new level at Dryden. It is very common to have an individual work on 10 different projects during a single pay period. Employee surveys taken at Dryden have identified work/life balance as the number one issue concerning employees. Further feedback from the employees indicated that project planning is the area needing the most improvement. In addition, employees have been encouraged to become more innovative, improve job skills, and seek ways to improve overall job efficiency. In order to deal with these challenges, DFRC management decided to adopt the CCPM system that is specifically designed to operate in a resource constrained multi-project environment. This paper will discuss in detail the rationale behind the selection of CCPM and the goals that will be achieved through this implementation. The paper will show how DFRC is tailoring the CCPM system to the flight research environment as well as laying out the implementation strategy. Results of the ongoing implementation will be discussed as well as change management challenges and organizational cultural changes. Finally this paper will present some recommendations on how this system could be used by selected NASA projects or centers.

  5. Outline of research project on nuclear fusion, 1985

    International Nuclear Information System (INIS)

    Uchida, Taijiro

    1985-08-01

    When the advance of nuclear fusion research during 10 years hereafter is predicted, the next project should start the research toward nuclear burning, adopt the diversified ways, and develop the research in wide related fields. The central subject such as the containment of plasma is studies with large experimental facilities, but in the related fields, the research subsidies must be utilized positively. The organization to perform the research compries 6 groups, 1) reactor materials and plasma-wall interactions 2) science and engineering of tritium, and influence on living things, 4) development of superconducting magnets, 5) fusion blanket engineering, and 6) design and assessment of thermonuclear reactors. The distribution and management of the scientific research subsidy are explained. All of the subjects of planned and publicly invited research a listed, and the researchers concerned, the amount of subsidy, the objective and the plan of execution in fiscal year 1984 of each research are outlined. (J.P.N.)

  6. Outline of research project on nuclear fusion, 1984

    International Nuclear Information System (INIS)

    Uchida, Taijiro

    1984-08-01

    When the advance of nuclear fusion research during 10 years hereafter is predicted, the next project should start the research toward nuclear burning, adopt the diversified ways, a nd develop the research in wide related fields. The central subject such as the containment of plasma is studies with large experimental facilities, but in the related fields, the research subsidies must be utilized positively. The organization to perform the research compries 6 groups, 1) reactor materials and plasma-wall interaction, 2) science and engineering of tritium and influence on living things, 3) fundamentals of core control, 4) development of superconducting magnets, 5) fusion blanket engineering, and 6) design and assessment of thermonuclear reactors. The distribution and management of the scientific research subsidy are explained. All of the subjects of planned and publicly invited research a listed, and the researchers concerned, the amount of subsidy, the objective and the plan of execution in fiscal 1983 of each research are outlined. (J.P.N.)

  7. Energy research projects in the Nordic countries - catalogue 1983

    International Nuclear Information System (INIS)

    1983-01-01

    The Nordic energy ministers at their meeting February 9, 1982 agreed upon a working plan for the Nordic energy cooperation. As part of this plan a contact group was established in order to maintain coordination and cooperation within the area of energy research and development. This group decided April 1982 to establish a catalogue of energy research projects in the Nordic countries. A pilot catalogue was published in June 1982. The 1983 catalogue gives an up-to-date survey of energy research and development projects in the Nordic countries. About 2125 projects are described, and information is given on investigator(s), performing organization, financing body, funds, and period. The catalogue is prepared by the Nordic energy libraries through their cooperation in Nordic Atomic Libraries Joint Secretariat. The information is also included in the data base Nordic Energy Index (NEI), which is online accessible at I/S Datacentralen, Copenhagen, via EURONET, SCANNET, TYMNET, AND TELENET. (BP)

  8. Research on bidding quotation game of international project

    Science.gov (United States)

    Lin, Tao; Xu, Xin

    2017-04-01

    Bidding competition of international projects is more and more fierce currently. However, China started late relatively in the field, it is still lack of experience in the aspect of participation in bidding of international projects, and more effective bidding quotation system is not formed till present. Therefore, China can not win through systemic bidding quotation methods compared with many powerful bidding enterprises in the international field. Research on the field is also focused by many aspects as a result. It is urgent to solve related problems. Game theory is combined for analyzing the effectiveness and operability of bidding quotation models mainly based on current situation of bidding market in China international projects during research process in the paper. The research starts with the perspective of bidders for analyzing their game with tenderers and other bidders. The results have operational value aiming at bidders.

  9. Congressional hearing reviews NSF major research and facilities projects

    Science.gov (United States)

    Showstack, Randy

    2012-03-01

    An 8 March congressional hearing about the U.S. National Science Foundation's Major Research Equipment and Facilities Construction (NSF MREFC) account focused on fiscal management and accountability of projects in that account and reviewed concerns raised by NSF's Office of Inspector General (OIG). NSF established the MREFC account in 1995 to better plan and manage investments in major equipment and facilities projects, which can cost from tens of millions to hundreds of millions of dollars, and the foundation has funded 17 MREFC projects since then. The Obama administration's proposed fiscal year (FY) 2013 budget includes funding for four MREFC projects: Advanced Laser Gravitational-Wave Observatory (AdvLIGO), Advanced Technology Solar Telescope (ATST), National Ecological Observatory (NEON), and Ocean Observatories Initiative (OOI). The hearing, held by a subcommittee of the House of Representatives' Committee on Science, Space, and Technology, reviewed management oversight throughout the life cycles of MREFC projects and concerns raised in recent OIG reports about the use of budget contingency funds. NSF's February 2012 manual called "Risk management guide for large facilities" states that cost contingency is "that portion of the project budget required to cover `known unknowns,'" such as planning and estimating errors and omissions, minor labor or material price fluctuations, and design developments and changes within the project scope. Committee members acknowledged measures that NSF has made to improve the MREFC oversight process, but they also urged the agency to continue to take steps to ensure better project management.

  10. Lower Columbia River Terminal Fisheries Research Project : Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1995-04-01

    This notice announces BPA`S`s decision to fund the Oregon Department of Fish and Wildlife (ODFW), the Washington Department of Fish and Wildlife (WDFW), and the Clatsop Economic Development Committee for the Lower Columbia River Terminal Fisheries Research Project (Project). The Project will continue the testing of various species/stocks, rearing regimes, and harvest options for terminal fisheries, as a means to increase lower river sport and commercial harvest of hatchery fish, while providing both greater protection of weaker wild stocks and increasing the return of upriver salmon runs to potential Zone 6 Treaty fisheries. The Project involves relocating hatchery smolts to new, additional pen locations in three bays/sloughs in the lower Columbia River along both the Oregon and Washington sides. The sites are Blind Slough and Tongue Point in Clatsop County, Oregon, and Grays Bay/Deep River, Wahkiakum County, Washington. The smolts will be acclimated for various lengths of time in the net pens and released from these sites. The Project will expand upon an existing terminal fisheries project in Youngs Bay, Oregon. The Project may be expanded to other sites in the future, depending on the results of this initial expansion. BPA`S has determined the project is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an environmental impact statement is not required, and BPA`S is issuing this FONSI.

  11. Research in progress: FY 1992. Summaries of projects

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    The Biological and Environmental Research (BER) Program of OHER has two main missions: (1) to develop the knowledge base necessary to identify, understand, and anticipate the long-term health and environmental consequences of energy use and development and (2) to utilize the Department`s unique scientific and technological capabilities to solve major scientific problems in medicine, biology, and the environment. These missions reflect a commitment to develop the beneficial uses of advanced energy technologies while at the same time assuring that any potentially adverse health and environmental impacts of the Nation`s energy policies are fully identified and understood. The BER Program includes research in atmospheric, marine, and terrestrial processes, including the linkage between the use in greenhouse gases, carbon dioxide, and regional and global climate change; in molecular and subcellular mechanisms underlying human somatic and genetic processes and their responses to energy-related environmental toxicants; in nuclear medicine, structural biology, the human genome, measurement sciences and instrumentation, and other areas that require the unique capabilities of the Department`s laboratory system. The principal areas of research are Health Research and Environmental Research.

  12. Using Biological-Control Research in the Classroom to Promote Scientific Inquiry & Literacy

    Science.gov (United States)

    Richardson, Matthew L.; Richardson, Scott L.; Hall, David G.

    2012-01-01

    Scientists researching biological control should engage in education because translating research programs into classroom activities is a pathway to increase scientific literacy among students. Classroom activities focused on biological control target all levels of biological organization and can be cross-disciplinary by drawing from subject areas…

  13. Crowd-sourced Archaeological Research: The MicroPasts Project

    Directory of Open Access Journals (Sweden)

    Chiara Bonacchi

    2014-10-01

    Full Text Available This paper offers a brief introduction to MicroPasts, a web-enabled crowd-sourcing and crowd-funding project whose overall goal is to promote the collection and use of high quality research data via institutional and community collaborations, both on- and off-line. In addition to introducing this initiative, the discussion below is a reflection of its lead author’s core contribution to the project and will dwell in more detail on one particular aspect of MicroPasts: its relevance to research and practice in public archaeology, cultural policy and heritage studies.

  14. Multimillion Dollar Construction Project Completed in Glenn's Icing Research Tunnel

    Science.gov (United States)

    Kevdzija, Susan L.

    2001-01-01

    Over the last year, the Glenn Research Center's Icing Research Tunnel (IRT) underwent a major $5.2 million rehabilitation project as part of the Construction of Facilities program. The scope of the project included redesign and replacement of the 55-yr-old heat exchanger, the addition of fan outlet guide vanes for flow conditioning downstream of the 25-ft-diameter fan, and redesign and replacement of the C and D corner-turning vanes. The purpose of the rehabilitation was to replace old portions of the infrastructure and to improve the aerodynamic flow quality in the tunnel.

  15. Data management for community research projects: A JGOFS case study

    Science.gov (United States)

    Lowry, Roy K.

    1992-01-01

    Since the mid 1980s, much of the marine science research effort in the United Kingdom has been focused into large scale collaborative projects involving public sector laboratories and university departments, termed Community Research Projects. Two of these, the Biogeochemical Ocean Flux Study (BOFS) and the North Sea Project incorporated large scale data collection to underpin multidisciplinary modeling efforts. The challenge of providing project data sets to support the science was met by a small team within the British Oceanographic Data Centre (BODC) operating as a topical data center. The role of the data center was to both work up the data from the ship's sensors and to combine these data with sample measurements into online databases. The working up of the data was achieved by a unique symbiosis between data center staff and project scientists. The project management, programming and data processing skills of the data center were combined with the oceanographic experience of the project communities to develop a system which has produced quality controlled, calibrated data sets from 49 research cruises in 3.5 years of operation. The data center resources required to achieve this were modest and far outweighed by the time liberated in the scientific community by the removal of the data processing burden. Two online project databases have been assembled containing a very high proportion of the data collected. As these are under the control of BODC their long term availability as part of the UK national data archive is assured. The success of the topical data center model for UK Community Research Project data management has been founded upon the strong working relationships forged between the data center and project scientists. These can only be established by frequent personal contact and hence the relatively small size of the UK has been a critical factor. However, projects covering a larger, even international scale could be successfully supported by a

  16. Implications of Plasmodium vivax Biology for Control, Elimination, and Research

    Science.gov (United States)

    Olliaro, Piero L.; Barnwell, John W.; Barry, Alyssa; Mendis, Kamini; Mueller, Ivo; Reeder, John C.; Shanks, G. Dennis; Snounou, Georges; Wongsrichanalai, Chansuda

    2016-01-01

    This paper summarizes our current understanding of the biology of Plasmodium vivax, how it differs from Plasmodium falciparum, and how these differences explain the need for P. vivax-tailored interventions. The article further pinpoints knowledge gaps where investments in research are needed to help identify and develop such specific interventions. The principal obstacles to reduce and eventually eliminate P. vivax reside in 1) its higher vectorial capacity compared with P. falciparum due to its ability to develop at lower temperature and over a shorter sporogonic cycle in the vector, allowing transmission in temperate zones and making it less sensitive to vector control measures that are otherwise effective on P. falciparum; 2) the presence of dormant liver forms (hypnozoites), sustaining multiple relapsing episodes from a single infectious bite that cannot be diagnosed and are not susceptible to any available antimalarial except primaquine, with routine deployment restricted by toxicity; 3) low parasite densities, which are difficult to detect with current diagnostics leading to missed diagnoses and delayed treatments (and protracted transmission), coupled with 4) transmission stages (gametocytes) occurring early in acute infections, before infection is diagnosed. PMID:27799636

  17. Dynamic models in research and management of biological invasions.

    Science.gov (United States)

    Buchadas, Ana; Vaz, Ana Sofia; Honrado, João P; Alagador, Diogo; Bastos, Rita; Cabral, João A; Santos, Mário; Vicente, Joana R

    2017-07-01

    Invasive species are increasing in number, extent and impact worldwide. Effective invasion management has thus become a core socio-ecological challenge. To tackle this challenge, integrating spatial-temporal dynamics of invasion processes with modelling approaches is a promising approach. The inclusion of dynamic processes in such modelling frameworks (i.e. dynamic or hybrid models, here defined as models that integrate both dynamic and static approaches) adds an explicit temporal dimension to the study and management of invasions, enabling the prediction of invasions and optimisation of multi-scale management and governance. However, the extent to which dynamic approaches have been used for that purpose is under-investigated. Based on a literature review, we examined the extent to which dynamic modelling has been used to address invasions worldwide. We then evaluated how the use of dynamic modelling has evolved through time in the scope of invasive species management. The results suggest that modelling, in particular dynamic modelling, has been increasingly applied to biological invasions, especially to support management decisions at local scales. Also, the combination of dynamic and static modelling approaches (hybrid models with a spatially explicit output) can be especially effective, not only to support management at early invasion stages (from prevention to early detection), but also to improve the monitoring of invasion processes and impact assessment. Further development and testing of such hybrid models may well be regarded as a priority for future research aiming to improve the management of invasions across scales. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. BRIC-100VC Biological Research in Canisters (BRIC)-100VC

    Science.gov (United States)

    Richards, Stephanie E.; Levine, Howard G. (Compiler); Romero, Vergel

    2016-01-01

    The Biological Research in Canisters (BRIC) is an anodized-aluminum cylinder used to provide passive stowage for investigations of the effects of space flight on small specimens. The BRIC 100 mm petri dish vacuum containment unit (BRIC-100VC) has supported Dugesia japonica (flatworm) within spring under normal atmospheric conditions for 29 days in space and Hemerocallis lilioasphodelus L. (daylily) somatic embryo development within a 5% CO2 gaseous environment for 4.5 months in space. BRIC-100VC is a completely sealed, anodized-aluminum cylinder (Fig. 1) providing containment and structural support of the experimental specimens. The top and bottom lids of the canister include rapid disconnect valves for filling the canister with selected gases. These specialized valves allow for specific atmospheric containment within the canister, providing a gaseous environment defined by the investigator. Additionally, the top lid has been designed with a toggle latch and O-ring assembly allowing for prompt sealing and removal of the lid. The outside dimensions of the BRIC-100VC canisters are 16.0 cm (height) x 11.4 cm (outside diameter). The lower portion of the canister has been equipped with sufficient storage space for passive temperature and relative humidity data loggers. The BRIC- 100VC canister has been optimized to accommodate standard 100 mm laboratory petri dishes or 50 mL conical tubes. Depending on storage orientation, up to 6 or 9 canisters have been flown within an International Space Station (ISS) stowage locker.

  19. Implications of Plasmodium vivax Biology for Control, Elimination, and Research.

    Science.gov (United States)

    Olliaro, Piero L; Barnwell, John W; Barry, Alyssa; Mendis, Kamini; Mueller, Ivo; Reeder, John C; Shanks, G Dennis; Snounou, Georges; Wongsrichanalai, Chansuda

    2016-12-28

    This paper summarizes our current understanding of the biology of Plasmodium vivax, how it differs from Plasmodium falciparum, and how these differences explain the need for P. vivax-tailored interventions. The article further pinpoints knowledge gaps where investments in research are needed to help identify and develop such specific interventions. The principal obstacles to reduce and eventually eliminate P. vivax reside in 1) its higher vectorial capacity compared with P. falciparum due to its ability to develop at lower temperature and over a shorter sporogonic cycle in the vector, allowing transmission in temperate zones and making it less sensitive to vector control measures that are otherwise effective on P. falciparum; 2) the presence of dormant liver forms (hypnozoites), sustaining multiple relapsing episodes from a single infectious bite that cannot be diagnosed and are not susceptible to any available antimalarial except primaquine, with routine deployment restricted by toxicity; 3) low parasite densities, which are difficult to detect with current diagnostics leading to missed diagnoses and delayed treatments (and protracted transmission), coupled with 4) transmission stages (gametocytes) occurring early in acute infections, before infection is diagnosed. © The American Society of Tropical Medicine and Hygiene.

  20. Harvard Personal Genome Project: lessons from participatory public research

    Science.gov (United States)

    2014-01-01

    Background Since its initiation in 2005, the Harvard Personal Genome Project has enrolled thousands of volunteers interested in publicly sharing their genome, health and trait data. Because these data are highly identifiable, we use an ‘open consent’ framework that purposefully excludes promises about privacy and requires participants to demonstrate comprehension prior to enrollment. Discussion Our model of non-anonymous, public genomes has led us to a highly participatory model of researcher-participant communication and interaction. The participants, who are highly committed volunteers, self-pursue and donate research-relevant datasets, and are actively engaged in conversations with both our staff and other Personal Genome Project participants. We have quantitatively assessed these communications and donations, and report our experiences with returning research-grade whole genome data to participants. We also observe some of the community growth and discussion that has occurred related to our project. Summary We find that public non-anonymous data is valuable and leads to a participatory research model, which we encourage others to consider. The implementation of this model is greatly facilitated by web-based tools and methods and participant education. Project results are long-term proactive participant involvement and the growth of a community that benefits both researchers and participants. PMID:24713084

  1. Harvard Personal Genome Project: lessons from participatory public research.

    Science.gov (United States)

    Ball, Madeleine P; Bobe, Jason R; Chou, Michael F; Clegg, Tom; Estep, Preston W; Lunshof, Jeantine E; Vandewege, Ward; Zaranek, Alexander; Church, George M

    2014-02-28

    Since its initiation in 2005, the Harvard Personal Genome Project has enrolled thousands of volunteers interested in publicly sharing their genome, health and trait data. Because these data are highly identifiable, we use an 'open consent' framework that purposefully excludes promises about privacy and requires participants to demonstrate comprehension prior to enrollment. Our model of non-anonymous, public genomes has led us to a highly participatory model of researcher-participant communication and interaction. The participants, who are highly committed volunteers, self-pursue and donate research-relevant datasets, and are actively engaged in conversations with both our staff and other Personal Genome Project participants. We have quantitatively assessed these communications and donations, and report our experiences with returning research-grade whole genome data to participants. We also observe some of the community growth and discussion that has occurred related to our project. We find that public non-anonymous data is valuable and leads to a participatory research model, which we encourage others to consider. The implementation of this model is greatly facilitated by web-based tools and methods and participant education. Project results are long-term proactive participant involvement and the growth of a community that benefits both researchers and participants.

  2. Genetics as a modernization program: biological research at the Kaiser Wilhelm Institutes and the political economy of the Nazi State.

    Science.gov (United States)

    Gausemeier, Bernd

    2010-01-01

    During the Third Reich, the biological institutes of the Kaiser Wilhelm Society (KWG, Kaiser-Wilhelm-Gesellschaft) underwent a substantial reorganization and modernization. This paper discusses the development of projects in the fields of biochemical genetics, virus research, radiation genetics, and plant genetics that were initiated in those years. These cases exemplify, on the one hand, the political conditions for biological research in the Nazi state. They highlight how leading scientists advanced their projects by building close ties with politicians and science-funding organizations and companies. On the other hand, the study examines how the contents of research were shaped by, and how they contributed to, the aims and needs of the political economy of the Nazi system. This paper therefore aims not only to highlight basic aspects of scientific development under Nazism, but also to provide general insights into the structure of the Third Reich and the dynamics of its war economy.

  3. Quantum Biology at the Cellular Level - elements of the research program

    OpenAIRE

    Bordonaro, Michael; Ogryzko, Vasily

    2013-01-01

    Quantum Biology is emerging as a new field at the intersection between fundamental physics and biology, promising novel insights into the nature and origin of biological order. We discuss several elements of QBCL (Quantum Biology at Cellular Level), a research program designed to extend the reach of quantum concepts to higher than molecular levels of biological organization. Key words. decoherence, macroscopic superpositions, basis-dependence, formal superposition, non-classical correlations,...

  4. Project resumes: biological effects from electric fields associated with high-voltage transmission lines

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    Abstracts of research projects are presented in the following areas: measurements and special facilities; cellular and subcellular studies; physiology; behavior; environmental effects; modeling, scaling and dosimetry; and high voltage direct current. (ACR)

  5. The progress of molecular biology in radiation research

    International Nuclear Information System (INIS)

    Wei Kang

    1989-01-01

    The recent progress in application of molecular biology techniques in the study of radiation biology is reviewed. The three sections are as follows: (1) the study of DNA damage on molecular level, (2) the molecular mechanism of radiation cell genetics, including chromosome abberation and cell mutation, (3) the study on DNA repair gene with DNA mediated gene transfer techniques

  6. University-Level Research Projects for High School Students

    Science.gov (United States)

    McConnell, Mark L.

    2000-01-01

    The goal of this project was to provide an opportunity for high school students to participate in university-level research projects. In this case, students from Pinkerton Academy (Derry, New Hampshire) were invited to participate in efforts to catalog data from the COMPTEL experiment on NASA's Compton Gamma-Ray Observatory (CGRO). These activities were part of a senior level honors course at Pinkerton. Although the success of this particular program was rather limited, we feel that the general concept is a sound one. In principle, the concept of partnerships between local schools and university researchers is one that could be especially attractive to soft money researchers. Programs can be carefully designed to benefit both the students and the research program.

  7. Can we combine symptom scales for collaborative research projects?

    LENUS (Irish Health Repository)

    Lyne, John P

    2012-02-01

    Collaborative research projects have the potential to answer important research questions, which may otherwise require huge resources, funding, and time to complete. There are several scales for measuring psychotic symptoms in schizophrenia and other psychotic disorders, with the Scale for Assessment of Positive Symptoms (SAPS), Scale for Assessment of Negative Symptoms (SANS), Positive and Negative Symptom Scale (PANSS), and the Brief Psychiatric Rating Scale (BPRS) being among the most commonly used. High quality research efforts have used these three scales in different projects, and in order to merge study efforts, some means of combining data from these scales may be necessary. We reviewed correlations in published studies for these three scales, finding them to be highly correlated, however on comparison of the three scales there were considerable clinical differences between them. The paper discusses potential methods for combining the scales in collaborative research, including use of the recently developed standardised remission criteria for schizophrenia.

  8. AICD -- Advanced Industrial Concepts Division Biological and Chemical Technologies Research Program. 1993 Annual summary report

    Energy Technology Data Exchange (ETDEWEB)

    Petersen, G.; Bair, K.; Ross, J. [eds.

    1994-03-01

    The annual summary report presents the fiscal year (FY) 1993 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1993 (ASR 93) contains the following: A program description (including BCTR program mission statement, historical background, relevance, goals and objectives), program structure and organization, selected technical and programmatic highlights for 1993, detailed descriptions of individual projects, a listing of program output, including a bibliography of published work, patents, and awards arising from work supported by BCTR.

  9. Biological and Chemical Technologies Research at OIT: Annual Summary Report, FY 1997

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, G. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    1998-03-01

    The annual summary report presents the fiscal year (FY) 1 997 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program. This BCTR program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1997 (ASR 97) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization; selected technical and programmatic highlights for 1 997; detailed descriptions of individual projects; and a listing of program output, including a bibliography of published work, patents, and awards arising from work supported by the program.

  10. Status of the RA research reactor decommissioning project

    International Nuclear Information System (INIS)

    Ljubenov, V.; Nikolic, D.; Pesic, M.; Milosevic, M.; Kostic, Lj.; Steljic, M.; Sotic, O.; Antic, D. . E-mail address of corresponding author: vladan@vin.bg.ac.yu; Ljubenov, V.)

    2005-01-01

    The 6.5 MW heavy water RA research reactor at the VINCA Institute of Nuclear Sciences operated from 1959 to 1984. After 18 years of extended shutdown in 2002 it was decided that the reactor shutdown should be final. Preliminary decommissioning activities have been initiated by the end of 2002 under the Technical Co-operation Programme of the International Atomic Energy Agency. The objective of the project is to implement safe, timely and cost-effective decommissioning of the RA reactor up to unrestricted use of the site. Decommissioning project is closely related to two other projects: Safe Removal of the RA Reactor Spent Nuclear Fuel and Radioactive Waste Management in VINCA Institute. The main phases of the project include preparation of the detailed decommissioning plan, radiological characterization of the reactor site, dismantling and removal of the reactor components and structures, decontamination, final radiological site survey and the documentation of all the activities in order to obtain the approval for unrestricted use of the facility site. In this paper a review of the activities related to the preparation and realization of the RA reactor decommissioning project is given. Status of the project's organizational and technical aspects as for July 2004 are presented and plans for the forthcoming phases of the project realization are outlined. (author)

  11. Biology panel: coming to a clinic near you. Translational research in radiation biology

    International Nuclear Information System (INIS)

    Travis, Elizabeth L.; Thames, Howard D.

    1996-01-01

    The explosion of knowledge in molecular biology coupled with the rapid and continuing development of molecular techniques allow a new level of research in radiation biology aimed at understanding the processes that govern radiation damage and response in both tumors and normal tissues. The challenge to radiation biologists and radiation oncologists is to use this knowledge to improve the therapeutic ratio in the management of human tumors by rapidly translating these new findings into clinical practice. This panel will focus on both sides of the therapeutic ratio coin, the manipulation of tumor control by manipulating the processes that control cell cycle regulation and apoptosis, and the reduction of normal tissue morbidity by applying the emerging information on the genetic basis of radiosensitivity. Apoptosis is a form of cell death believed to represent a minor component of the clinical effects of radiation. However, if apoptosis is regulated by anti-apoptotic mechanisms, then it may be possible to produce a pro-apoptotic phenotype in the tumor cell population by modulating the balance between pro- and anti-apoptotic mechanisms by pharmacological intervention. Thus signaling-based apoptosis therapy, designed to overcome the relative resistance to radiation-induced apoptosis, may improve the therapeutic ratio in the management of human tumors. The explosion of information concerning cell cycle regulation in both normal and tumor cells has provided the opportunity for insights into the mechanism of action of chemotherapeutic agents that can act as radiosensitizers. The second talk will explore the hypothesis that the dysregulation of cell cycle checkpoints in some cancers can be exploited to improve the therapeutic index of radiation sensitizers, specifically the fluoropyrimidines which appear to act at the G1/S transition. Finally, efforts to increase tumor control will be translated into clinical practice only if such treatments do not increase the complication

  12. Using UAVs to Conduct Student-led Research Projects

    Science.gov (United States)

    Olds, S. E.; Lewis, P. M., Jr.

    2016-12-01

    Recreational drones can inspire students to initiate research projects. These "toys" have a low cost (Arduino board, SABEL collects temperature, humidity, and GPS position. This presentation will provide examples of student-led investigations, instructions for building the SABEL sensor package, and the status of the new e-book compilation of student-focused activities using recreational drones to pursue science, math, engineering, and technology research investigations.

  13. Energy secretary's priorities include San Francisco area research projects

    CERN Multimedia

    Widener, A

    2003-01-01

    "Bay Area research labs got a big boost Monday when the Secretary of Energy unveiled his priorities for major research projects his agency hopes to fund over the next two decades. Among the agency's 28 top priorities are a major computer expansion and an experiment examining the expanding universe that could be housed at Lawrence Berkeley Lab and a powerful X-ray laser planned for the Stanford Linear Accelerator Center" (1 page).

  14. The SIMRAND methodology - Simulation of Research and Development Projects

    Science.gov (United States)

    Miles, R. F., Jr.

    1984-01-01

    In research and development projects, a commonly occurring management decision is concerned with the optimum allocation of resources to achieve the project goals. Because of resource constraints, management has to make a decision regarding the set of proposed systems or tasks which should be undertaken. SIMRAND (Simulation of Research and Development Projects) is a methodology which was developed for aiding management in this decision. Attention is given to a problem description, aspects of model formulation, the reduction phase of the model solution, the simulation phase, and the evaluation phase. The implementation of the considered approach is illustrated with the aid of an example which involves a simplified network of the type used to determine the price of silicon solar cells.

  15. Interdisciplinary physics research in the Japanese Hadron Project

    International Nuclear Information System (INIS)

    Yamazaki, Toshimitsu.

    1990-09-01

    The Japanese Hadron Project (JHP) is a large future plan of interdisciplinary and international scope, aimed at basic physics research by creating and using various secondary unstable particle beams such as mesons, muons, neutrons and accelerated exotic nuclei. It comprises a high-intensity proton linac of 1 GeV, a compressor/stretcher ring and an ISOL/accelerator to deliver beams to MESON, NEUTRON and EXOTIC NUCLEI arena's. In addition, as the present ongoing project, we are pushing KAON arena based on the KEK 12 GeV proton synchrotron. The present paper describes the scientific motivation and technological bases for this future project as well as the presently going pre-JHP research activities. (author)

  16. Project Management Practices as a Subject of Research for CSCW

    DEFF Research Database (Denmark)

    Bossen, Claus; Leimbach, Timo

    2017-01-01

    The ‘project’ is a prevalent form for organising endeavours of construction, innovation, IT development and organisational change. ‘Projects’ involve coordination and cooperation between colocated and distributed actors, and are relevant for CSCW (computer supported cooperative work) research...... as a particular kind of cooperative work. A survey of CSCW publications only identified 26 papers that explicitly address project management (PM), of which most primarily focus on IT development. We argue that CSCW’s conceptual and methodological tools can make significant contributions to PM research, practice...... on computational support for project work and management. In all, we argue that CSCW can advance our understanding of project work and management and the design of adequate computational support....

  17. Undergraduate Research Involving Deaf and Hard-of-Hearing Students in Interdisciplinary Science Projects

    Directory of Open Access Journals (Sweden)

    Todd Pagano

    2015-05-01

    Full Text Available Scientific undergraduate research in higher education often yields positive outcomes for student and faculty member participants alike, with underrepresented students often showing even more substantial gains (academic, professional, and personal as a result of the experience. Significant success can be realized when involving deaf and hard-of-hearing (d/hh undergraduate students, who are also vastly underrepresented in the sciences, in interdisciplinary research projects. Even d/hh Associate degree level students and those in the first two years of their postsecondary careers can contribute to, and benefit from, the research process when faculty mentors properly plan/design projects. We discuss strategies, including the dissemination/communication of research results, for involving these students in research groups with different communication dynamics and share both findings of our research program and examples of successful chemical and biological research projects that have involved d/hh undergraduate students. We hope to stimulate a renewed interest in encouraging diversity and involving students with disabilities into higher education research experiences globally and across multiple scientific disciplines, thus strengthening the education and career pipeline of these students.

  18. Student Research Projects Inhibiting Factors from the Students Perspective

    Directory of Open Access Journals (Sweden)

    Laila Nikrooz

    2012-09-01

    Full Text Available Background & Objective: Identifying the research barriers and assess the ability of students to use the university services and facilities is crucial to promote research activities. Present study was carried out to determine the inhibiting factors influencing the student's research projects from the view point of Yasuj University of Medical Sciences students in 2008. Materials & Methods: In this cross sectional study 96 students of Yasuj Medical University were selected by stratified random sampling. The data were collected by validate & reliable questionnaire, containing demographic information, inhibiting factors related to students (personal and organization. The data were analyzed by SPSS software. Results: The mean scores against the personal barriers and the organizational barriers questions were 43.23±12.96 and 62.58±12.08 respectively. There was a significant difference between personal and organizational barriers (P<0.001 and personal barriers were more important. According to the results, the student's inadequate skills & knowledge of research methodology and lack of awareness of research topics were the most prevalent personal barriers. The most prevalent organizational barriers were unavailability of research consulters, inadequate research skills of consulter, insufficient facilities & equipment and lack of motivating staff & faculties. Other variables such as gender, subject of study and research experience are mentioned in the full text. Conclusion: This study showed that the personal barriers were more important than organizational barriers which interfere with the student's research projects. This can be corrected and controlled by teachers, faculty members, university officials and students, themselves.

  19. Laboratory technology research - abstracts of FY 1997 projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. A distinguishing feature of the ER multi-program national laboratories is their ability to integrate broad areas of science and engineering in support of national research and development goals. The LTR program leverages this strength for the Nation`s benefit by fostering partnerships with US industry. The partners jointly bring technology research to a point where industry or the Department`s technology development programs can pursue final development and commercialization. Projects supported by the LTR program are conducted by the five ER multi-program laboratories. These projects explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials; intelligent processing/manufacturing research; and sustainable environments.

  20. AN OPTICAL CHARACTER RECOGNITION RESEARCH AND DEMONSTRATION PROJECT.

    Science.gov (United States)

    1968

    RESEARCH AND DEVELOPMENT OF PROTOTYPE LIBRARY SYSTEMS WHICH UTILIZE OPTICAL CHARACTER RECOGNITION INPUT HAS CENTERED AROUND OPTICAL PAGE READERS AND DOCUMENT READERS. THE STATE-OF-THE-ART OF BOTH THESE OPTICAL SCANNERS IS SUCH THAT BOTH ARE ACCEPTABLE FOR LIBRARY INPUT PREPARATION. A DEMONSTRATION PROJECT UTILIZING THE TWO TYPES OF READERS, SINCE…

  1. Designing and conducting health system research projects, volume ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    These 'green modules'* found their way to Malaysia, where Indra ..... They determine nutritional and hygiene practices, alert children to dangers, provide care in ... money from taxes and donor agencies to finance the health care system. .... The principle of cost-effectiveness is important in the selection of research projects.

  2. The JET project and the European fusion research programme

    International Nuclear Information System (INIS)

    Wuester, H.-O.

    1984-01-01

    The paper concerns the Joint European Torus (JET) project and the European Fusion Research Programme. Fusion as an energy source and commercial fusion power are briefly discussed. The main features of the JET apparatus and the tokamak magnetic field configuration are given. Also described are the specific aims of JET, and the proposed future fusion reactor programme. (U.K.)

  3. Comparison of Scientific Research Projects of Education Faculties

    Science.gov (United States)

    Altunay, Esen; Tonbul, Yilmaz

    2015-01-01

    Many studies indicate that knowledge and knowledge production are the main predictors of social development, welfare and the ability to face the future with confidence. It could be argued that knowledge production is mainly carried out by universities. This study compares 1266 scientific research projects (SRPs) completed by faculties of education…

  4. ChE Undergraduate Research Projects in Biomedical Engineering.

    Science.gov (United States)

    Stroeve, Pieter

    1981-01-01

    Describes an undergraduate research program in biomedical engineering at the State University of New York at Buffalo. Includes goals and faculty comments on the program. Indicates that 58 percent of projects conducted between 1976 and 1980 have been presented at meetings or published. (SK)

  5. An Issues-Based Research Project: National Goals on Trial.

    Science.gov (United States)

    DeVille, Priscilla; And Others

    This paper summarizes the results of a research project completed by three doctoral students enrolled in an advanced curriculum development course at the University of Southern Mississippi (Hattiesburg). The students used a mock trial format to consider reasons to support establishment of a national curriculum (concerning the American public's…

  6. The Contribution of Current Research and Development Projects

    Science.gov (United States)

    Townsend, H. E. R.

    1973-01-01

    Reviews recent projects on the education of immigrants within the framework of the six suggestions for research made by the Select Committee on Race Relations and Immigrations; e.g. the effects on children of various educational arrangements for immigrants; methods of teaching race relations in schools; and others. (Author/JM)

  7. Authentic student research projects on physics and the human body

    NARCIS (Netherlands)

    Heck, A.; Ellermeijer, T.; Kędzierska, E.

    2010-01-01

    Students in Dutch senior secondary education are obliged to perform their own research project of approximately 80 hours. They are stimulated to choose the topic themselves (preferably with relations to two subjects, like physics and mathematics) and have a lot of freedom in the design of the

  8. As our earliest supported research projects move toward completion ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    CCAA

    and evaluation of farmer field schools” for southern and central ... CCAA research and capacity building projects, including papers, book chapters, newsletters, bulletins and theses .... climatique et à l'action de l'homme : mémoire de master de.

  9. BrisSynBio: a BBSRC/EPSRC-funded Synthetic Biology Research Centre.

    Science.gov (United States)

    Sedgley, Kathleen R; Race, Paul R; Woolfson, Derek N

    2016-06-15

    BrisSynBio is the Bristol-based Biotechnology and Biological Sciences Research Council (BBSRC)/Engineering and Physical Sciences Research Council (EPSRC)-funded Synthetic Biology Research Centre. It is one of six such Centres in the U.K. BrisSynBio's emphasis is on rational and predictive bimolecular modelling, design and engineering in the context of synthetic biology. It trains the next generation of synthetic biologists in these approaches, to facilitate translation of fundamental synthetic biology research to industry and the clinic, and to do this within an innovative and responsible research framework. © 2016 The Author(s).

  10. Chemical and biological warfare. Should defenses be researched and deployed?

    Science.gov (United States)

    Orient, J M

    1989-08-04

    The threat of chemical and biological weapons of mass destruction has intensified because of improved delivery systems and advances in chemistry, genetics, and other sciences. Possible US responses to this threat include deterrence, defenses, and/or disarmament, including a reaffirmation of the Biological and Toxin Weapons Convention of 1972, which is now in jeopardy. This article discusses the history of chemical and biological warfare, existing and potential weapons, the proliferation of weapons and delivery systems, ways to prevent the use of these weapons, and ways to protect populations from their effects.

  11. Managing environmental enhancement plans for individual research projects at a national primate research center.

    Science.gov (United States)

    Thom, Jinhee P; Crockett, Carolyn M

    2008-05-01

    We describe a method for managing environmental enhancement plans for individual research projects at a national primate research center where most monkeys are assigned to active research projects. The Psychological Well-being Program (PWB) at the University of Washington National Primate Research Center developed an Environmental Enhancement Plan form (EEPL) that allows PWB to quantify and track changes in enrichment allowances over time while ensuring that each animal is provided with as much enrichment as possible without compromising research. Very few projects involve restrictions on toys or perches. Some projects have restrictions on food treats and foraging, primarily involving the provision of these enrichments by research staff instead of husbandry staff. Restrictions are not considered exemptions unless they entirely prohibit an element of the University of Washington Environmental Enhancement Plan (UW EE Plan). All exemptions must be formally reviewed and approved by the institutional animal care and use committee. Most exemptions from elements of the UW EE Plan involve social housing. Between 2004 and 2006, the percentage of projects with no social contact restrictions increased by 1%, but those prohibiting any tactile social contact declined by 7%, and projects permitting tactile social contact during part of the study increased by 9%. The EEPL form has facilitated informing investigators about the enrichment their monkeys will receive if no restrictions or exemptions are requested and approved. The EEPL form also greatly enhances PWB's ability to coordinate the specific enrichment requirements of a project.

  12. The CARE project (Coordinated Accelerator Research in Europe)

    International Nuclear Information System (INIS)

    Napoly, Olivier

    2006-01-01

    CARE, an ambitious and coordinated project of accelerator research and developments oriented towards High Energy Physics projects, has been launched in January 2004 by the main European laboratories and the European Commission with the 6th Framework Programme. This project aims at improving existing infrastructures dedicated to future projects such as linear colliders, upgrades of hadron colliders and high intensity proton drivers An important part of this programme is devoted to advancing the performance of the superconducting technology, both in the fields of RF cavities for electron and proton acceleration and of high field magnets, as well as to developing high intensity electron and proton injectors. We describe the plans of the four main Joint Research Activities and report on the results and progress obtained so far. The CARE project also includes three adjacent Networking Activities whose main goal is to organize a forum of discussions and to provide the strategic plans in the fields of the Linear Collider, intense Neutrino Beams, and future Hadron Colliders

  13. Tumor Biology and Immunology | Center for Cancer Research

    Science.gov (United States)

    Tumor Biology and Immunology The Comparative Brain Tumor Consortium is collaborating with National Center for Advanced Translational Sciences to complete whole exome sequencing on canine meningioma samples. Results will be published and made publicly available.

  14. [Research progress of mammalian synthetic biology in biomedical field].

    Science.gov (United States)

    Yang, Linfeng; Yin, Jianli; Wang, Meiyan; Ye, Haifeng

    2017-03-25

    Although still in its infant stage, synthetic biology has achieved remarkable development and progress during the past decade. Synthetic biology applies engineering principles to design and construct gene circuits uploaded into living cells or organisms to perform novel or improved functions, and it has been widely used in many fields. In this review, we describe the recent advances of mammalian synthetic biology for the treatment of diseases. We introduce common tools and design principles of synthetic gene circuits, and then we demonstrate open-loop gene circuits induced by different trigger molecules used in disease diagnosis and close-loop gene circuits used for biomedical applications. Finally, we discuss the perspectives and potential challenges of synthetic biology for clinical applications.

  15. Applications of neutron scattering in molecular biological research

    International Nuclear Information System (INIS)

    Nierhaus, K.H.

    1984-01-01

    The study of the molecular structure of biological materials by neutron scattering is described. As example the results of the study of the components of a ribosome of Escherichia coli are presented. (HSI) [de

  16. Biometry: the principles and practice of statistics in biological research

    National Research Council Canada - National Science Library

    Sokal, R.R; Rohlf, F.J

    1969-01-01

    In this introductory textbook, with its companion volume of tables, the authors provide a balanced presentation of statistical methodology for the descriptive, experimental, and analytical study of biological phenomena...

  17. On-going research projects at Ankara Nuclear Research Center in agriculture and animal science

    International Nuclear Information System (INIS)

    Tukenmez, I.

    2004-01-01

    The projects in progress conducted by the Center comprise nuclear-aided researches in soil fertility, plant nutrition, plant protection, improvement of field crops, improvement of horticultural plants and forest trees by mutation breeding, in vitro culture technique with mutagen treatments, use of phosphogypsum in soil amelioration, sterilization of medical supplies, wastewater treatment, animal nutrition, animal health and productivity and accreditation. The on-going main projects involving several sub-projects with the above subjects were summarized for possible future collaborations. (author)

  18. Biological research work within the Association of the Government-Sponsored Research Institutions (AGF)

    International Nuclear Information System (INIS)

    1991-01-01

    Six of the thirteen government-sponsored research institutions in the Federal Republic of Germany carry out research work for the protection of the population against the harmful effects of ionizing radiation. Their activities in this field concentrate on the following four points of main interest: analysis of radiation-induced processes resulting in biological radiation injury; description and analysis of complex radiation effects on man; medical applications of ionizing radiation for diagnosis and therapy; concepts and methods for radiological protection. The work reported reviews the main problems encountered in the above-mentioned subject fields and presents examples of significant results, with illustrations. The original research papers and their authors are listed separately under the four points of main interest. (orig./MG) [de

  19. Implementation of a Collaborative Series of Classroom-Based Undergraduate Research Experiences Spanning Chemical Biology, Biochemistry, and Neurobiology

    Science.gov (United States)

    Kowalski, Jennifer R.; Hoops, Geoffrey C.; Johnson, R. Jeremy

    2016-01-01

    Classroom undergraduate research experiences (CUREs) provide students access to the measurable benefits of undergraduate research experiences (UREs). Herein, we describe the implementation and assessment of a novel model for cohesive CUREs focused on central research themes involving faculty research collaboration across departments. Specifically, we implemented three collaborative CUREs spanning chemical biology, biochemistry, and neurobiology that incorporated faculty members’ research interests and revolved around the central theme of visualizing biological processes like Mycobacterium tuberculosis enzyme activity and neural signaling using fluorescent molecules. Each CURE laboratory involved multiple experimental phases and culminated in novel, open-ended, and reiterative student-driven research projects. Course assessments showed CURE participation increased students’ experimental design skills, attitudes and confidence about research, perceived understanding of the scientific process, and interest in science, technology, engineering, and mathematics disciplines. More than 75% of CURE students also engaged in independent scientific research projects, and faculty CURE contributors saw substantial increases in research productivity, including increased undergraduate student involvement and academic outputs. Our collaborative CUREs demonstrate the advantages of multicourse CUREs for achieving increased faculty research productivity and traditional CURE-associated student learning and attitude gains. Our collaborative CURE design represents a novel CURE model for ongoing laboratory reform that benefits both faculty and students. PMID:27810870

  20. NORSTAR Project: Norfolk public schools student team for acoustical research

    Science.gov (United States)

    Fortunato, Ronald C.

    1987-01-01

    Development of the NORSTAR (Norfolk Public Student Team for Acoustical Research) Project includes the definition, design, fabrication, testing, analysis, and publishing the results of an acoustical experiment. The student-run program is based on a space flight organization similar to the Viking Project. The experiment will measure the scattering transfer of momentum from a sound field to spheres in a liquid medium. It is hoped that the experimental results will shed light on a difficult physics problem - the difference in scattering cross section (the overall effect of the sound wave scattering) for solid spheres and hollow spheres of differing wall thicknesses.

  1. Sandia, California Tritium Research Laboratory transition and reutilization project

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, T.B. [Sandia National Lab., Albuquerque, NM (United States)

    1997-02-01

    This paper describes a project within Sandia National Laboratory to convert the shut down Tritium Research Laboratory into a facility which could be reused within the laboratory complex. In the process of decommissioning and decontaminating the facility, the laboratory was able to save substantial financial resources by transferring much existing equipment to other DOE facilities, and then expeditiously implementing a decontamination program which has resulted in the building being converted into laboratory space for new lab programs. This project of facility reuse has been a significant financial benefit to the laboratory.

  2. 2011 Joint Science Education Project: Research Experience in Polar Science

    Science.gov (United States)

    Wilkening, J.; Ader, V.

    2011-12-01

    The Joint Science Education Project (JSEP), sponsored by the National Science Foundation, is a two-part program that brings together students and teachers from the United States, Greenland, and Denmark, for a unique cross-cultural, first-hand experience of the realities of polar science field research in Greenland. During JSEP, students experienced research being conducted on and near the Greenland ice sheet by attending researcher presentations, visiting NSF-funded field sites (including Summit and NEEM field stations, both located on the Greenland ice sheet), and designing and conducting research projects in international teams. The results of two of these projects will be highlighted. The atmospheric project investigated the differences in CO2, UVA, UVB, temperature, and albedo in different Arctic microenvironments, while also examining the interaction between the atmosphere and water present in the given environments. It was found that the carbon dioxide levels varied: glacial environments having the lowest levels, with an average concentration of 272.500 ppm, and non-vegetated, terrestrial environments having the highest, with an average concentration of 395.143 ppm. Following up on these results, it is planned to further investigate the interaction of the water and atmosphere, including water's role in the uptake of carbon dioxide. The ecology project investigated the occurrence of unusual large blooms of Nostoc cyanobacteria in Kangerlussuaq area lakes. The water chemistry of the lakes which contained the cyanobacteria and the lakes that did not were compared. The only noticeable difference was of the lakes' acidity, lakes containing the blooms had an average pH value of 8.58, whereas lakes without the blooms had an average pH value of 6.60. Further investigation of these results is needed to determine whether or not this was a cause or effect of the cyanobacteria blooms. As a next step, it is planned to attempt to grow the blooms to monitor their effects on

  3. Incentives for research. Three projects awarded the 'BP Energy Research Prize'

    Energy Technology Data Exchange (ETDEWEB)

    1980-07-01

    Three projects are described that have been awarded the BP-energy-research prize. These are: absorption heat pumps with a high heat ratio, fuels from sewage sludge, chemical heat storage of solar energy.

  4. Annual Report of the Tandem Accelerator Center, Nuclear and Solid State Research Project, University of Tsukuba

    International Nuclear Information System (INIS)

    1978-01-01

    In 1977, 12 UD Pelletron tandem accelerator has been operated by the University's researchers and engineers. Except for the tank opening for regular inspection we met twice the troubles which forced to change the accelerating tube. The experiences teach us that it needs about 20 days to finish the conditioning after changing the accelerating tube. A sputter ion source of new version is now being installed on the top floor. Two devices for the detection of X-rays were tested. An apparatus for bombardment of samples in air for biological and medical sciences has been successfully used. The subjects of researches on nuclear physics cover the light-ion reactions, heavy-ion reactions and nuclear spectroscopy. A special emphasis has been put on the measurements on vector- and tensor-analyzing powers in the light-ion reactions, because of a higher efficiency of the polarized ion source. Elaborate works on the heavy-ion reactions including the angular correlation patterns and excitation functions have been made in parallel. Papers of these works are now being prepared, a few having been published already. Moreover, in the University of Tsukuba, a new research system, called Special Research Project on Nuclear and Solid State Sciences Using Accelerated Beams (Nuclear and Solid State Research Project) started in 1978 and will continue for five years. In this research project, researchers from various Institutes in the University of Tsukuba, as well as visiting researchers from other institutions in Japan and from abroad, participate. Using a variety of accelerated beams, i.e. of heavy, light and polarized beams, this research project aims mainly at the high excitation, short life, transient and inhomogeneous states both in nuclear and extra-nuclear world. It covers both fundamental research in nuclear, atomic and solid state sciences as well as their application in various fields. (J.P.N.)

  5. Which Type of Inquiry Project Do High School Biology Students Prefer: Open or Guided?

    Science.gov (United States)

    Sadeh, Irit; Zion, Michal

    2012-10-01

    In teaching inquiry to high school students, educators differ on which method of teaching inquiry is more effective: Guided or open inquiry? This paper examines the influence of these two different inquiry learning approaches on the attitudes of Israeli high school biology students toward their inquiry project. The results showed significant differences between the two groups: Open inquiry students were more satisfied and felt they gained benefits from implementing the project to a greater extent than guided inquiry students. On the other hand, regarding documentation throughout the project, guided inquiry students believed that they conducted more documentation, as compared to their open inquiry peers. No significant differences were found regarding `the investment of time', but significant differences were found in the time invested and difficulties which arose concerning the different stages of the inquiry process: Open inquiry students believed they spent more time in the first stages of the project, while guided inquiry students believed they spent more time in writing the final paper. In addition, other differences were found: Open inquiry students felt more involved in their project, and felt a greater sense of cooperation with others, in comparison to guided inquiry students. These findings may help teachers who hesitate to teach open inquiry to implement this method of inquiry; or at least provide their students with the opportunity to be more involved in inquiry projects, and ultimately provide their students with more autonomy, high-order thinking, and a deeper understanding in performing science.

  6. Summary results of an assessment of research projects in the Nuclear Medicine Research program

    International Nuclear Information System (INIS)

    1988-01-01

    In May 1987, OHER management requested the Office of Program Analysis (OPA) to conduct a peer review of the projects of the DOE Nuclear Medicine Research program. This was done using procedures and a quantitative methodology OPA developed for assessing DOE research programs. Sixty-three individual nuclear medicine projects were reviewed by seven panels; one panel on isotopes and radioisotopes, three on radiopharmacology, two on clinical feasibility, and one on instrumentation. Each panel consisted of five to ten knowledgeable reviewers. 5 figs

  7. Research in Undergraduate Instruction: A Biotech Lab Project for Recombinant DNA Protein Expression in Bacteria

    Science.gov (United States)

    Brockman, Mark; Ordman, Alfred B.; Campbell, A. Malcolm

    1996-06-01

    In the sophomore-level Molecular Biology and Biotechnology course at Beloit College, students learn basic methods in molecular biology in the context of pursuing a semester-long original research project. We are exploring how DNA sequence affects expression levels of proteins. A DNA fragment encoding all or part of the guanylate monokinase (gmk) sequence is cloned into pSP73 and expressed in E. coli. A monoclonal antibody is made to gmk. The expression level of gmk is determined by SDS gel elctrophoresis, a Western blot, and an ELISA assay. Over four years, an increase in enrollment in the course from 9 to 34 students, the 85% of majors pursuing advanced degrees, and course evaluations all support the conclusion that involving students in research during undergraduate courses encourages them to pursue careers in science.

  8. Areas of research in radiation chemistry fundamental to radiation biology

    International Nuclear Information System (INIS)

    Powers, E.L.

    1980-01-01

    Among all the environmental hazards to which man is exposed, ionizing radiation is the most thoroughly investigated and the most responsibly monitored and controlled. Nevertheless, because of the importance of radiation in modern society from both the hazard as well as the utilitarian standpoints, much more information concerning the biological effects induced and their modification and reversal is required. Together with radiation physics, an understanding of radiation chemistry is necessary for full appreciation of biological effects of high and low energy radiations, and for the development of prophylactic, therapeutic and potentiating methods and techniques in biological organisms. The necessity of understanding the chemistry of any system, biological or not, that is to be manipulated and controlled, is so obvious as to make trivial a statement to that effect. If any natural phenomenon is to be put to our use, surely the elements of it must be studied and appreciated fully. In the preliminary statements of the various panels of this general group, the need for additional information on the basic radiation chemistry concerned in radiation-induced biological effects pervades throughout

  9. A German research project about applicable graphite cutting techniques

    International Nuclear Information System (INIS)

    Holland, D.; Quade, U.; Bach, F.W.; Wilk, P.

    2001-01-01

    In Germany, too, quite large quantities of irradiated nuclear graphite, used in research and prototype reactors, are waiting for an environmental way of disposal. While incineration of nuclear graphite does not seem to be a publicly acceptable way, cutting and packaging into ductile cast iron containers could be a suitable way of disposal in Germany. Nevertheless, the cutting of graphite is also a very difficult technique by which a large amount of secondary waste or dust might occur. An applicable graphite cutting technique is needed. Therefore, a group of 13 German partners, consisting of one university, six research reactor operators, one technical inspection authority, three engineering companies, one industrial cutting specialist and one commercial dismantling company, decided in 1999 to start a research project to develop an applicable technique for cutting irradiated nuclear graphite. Aim of the project is to find the most suitable cutting techniques for the existing shapes of graphite blocks with a minimum of waste production rate. At the same time it will be learned how to sample the dust and collect it in a filter system. The following techniques will be tested and evaluated: thermal cutting, water jet cutting, mechanical cutting with a saw, plasma arc cutting, drilling. The subsequent evaluation will concentrate on dust production, possible irradiation of staff, time and practicability under different constraints. This research project is funded by the German Minister of Education and Research under the number 02 S 7849 for a period of two years. A brief overview about the work to be carried out in the project will be given. (author)

  10. Consortium for Offshore Aviation Research : description of current projects

    International Nuclear Information System (INIS)

    Anon.

    1998-01-01

    The five projects which are currently underway or being evaluated through the Consortium for Offshore Aviation Research (COAR) were described. The projects are: (1) the use of narrow-beam, high intensity searchlights as approach aids for helicopter landings on helidecks in low visibility conditions, (2) establishment of a precipitation and fog characterization facility forecasting, (3) use of ice-phobic materials for airframe anti-icing, (4) use of differential global positioning satellite systems for offshore operations, and (5) the development of a virtual reality head-up-display for the approach to the Hibernia helideck (or any other helideck) to facilitate low visibility landings. Seed funding for these projects has been provided by the European Space Agency. Additional support is being provided by Hibernia, Petro-Canada, Husky Oil and Chevron Oil Canada. Initiatives to increase the number of partners are underway. 1 fig

  11. Research, design and development project Myoelectric Prosthesis of Upper Limb

    Energy Technology Data Exchange (ETDEWEB)

    Galiano, L; Montaner, E; Flecha, A [Bioparx, J Hernandez 1101, Parana, ERios (Argentina)

    2007-11-15

    A Research Design and Development Project was developed of a myoelectric prosthesis for a pediatric patient presenting congenital amputation of the left forearm below the elbow. A multidisciplinary work-team was formed for this goal, in order to solve the several (/various) aspects regarding this project (mechanical, ergonomics, electronics, physical). The prosthesis as an electromechanical device was divided in several blocks, trying to achieve a focused development for each stage, acording to requisites. A mechanical prototype of the prothesis was designed and built along with the circuitry needed for EMG aquisition, control logic and drivers. Having acomplished the previuos stages, the project is now dealing with the definitions of the interface between the prosthesis and the patient, with promising perspectives.

  12. Research, design and development project Myoelectric Prosthesis of Upper Limb

    International Nuclear Information System (INIS)

    Galiano, L; Montaner, E; Flecha, A

    2007-01-01

    A Research Design and Development Project was developed of a myoelectric prosthesis for a pediatric patient presenting congenital amputation of the left forearm below the elbow. A multidisciplinary work-team was formed for this goal, in order to solve the several (/various) aspects regarding this project (mechanical, ergonomics, electronics, physical). The prosthesis as an electromechanical device was divided in several blocks, trying to achieve a focused development for each stage, acording to requisites. A mechanical prototype of the prothesis was designed and built along with the circuitry needed for EMG aquisition, control logic and drivers. Having acomplished the previuos stages, the project is now dealing with the definitions of the interface between the prosthesis and the patient, with promising perspectives

  13. A Research Design for NASA-Funded Professional Development Projects

    Science.gov (United States)

    Bleicher, R. E.; Lambert, J.; Getty, S. R.

    2011-12-01

    This proposal outlines a research plan designed to measure gains in student learning resulting from their teachers participating in professional development. Project Description Misconceptions about global climate change (GCC) are prevalent in the general public (Kellstedt, Zahran, & Vedlitz, 2008; Washington & Cook, 2011). One solution is to provide high school students with a better grounding in the basic science and data that underlie GCC. The overarching goal of a NASA-funded project, Promoting Educational Leadership in Climate Change Literacy (PEL), is to increase GCC literacy in high school students. Research Design The research design is interpretative (Erickson, 2006), framed within a multi-method design, synthesizing both quantitative and qualitative data sources (Morse, 2003). Overall, the data will provide rich information about the PEL's impact on curriculum development, teacher pedagogical knowledge, and student learning. The expectancy-value theory of achievement motivation (E-V-C) (Fan, 2011; Wigfield & Eccles, 1994) provides a theoretical foundation for the research. Expectancy is the degree to which a teacher or student has reason to expect that they will be successful in school. Value indicates whether they think that performance at school will be worthwhile to them. Cost is the perceived sacrifices that must be undertaken, or factors that can inhibit, a successful performance at school. For students, data from an embedded E-V-C investigation will help articulate how E-V-C factors relate to student interest in science, continuing to study science, or embarking on STEM related careers. For teachers, the E-V-C measures will give insight into a key mediating variable on student achievement in science. The evaluation will seek to address research questions at the student and teacher levels. Table 1 presents a sample of research questions and data sources. This is a sample of a much larger set of questions that will be addressed in the project. Data

  14. Lessons learned from setting up the NOWESP research data base: Experiences in an interdisciplinary research project

    Science.gov (United States)

    Radach, Günther; Gekeler, Jens

    1996-09-01

    Research carried out within the framework of the MAST project NOWESP (North-West European Shelf Programme) was based on a multi-parameter data set of existing marine data, relevant for estimating trends, variability and fluxes on the Northwest European Shelf. The data sets were provided by the partners of the project. Additional data sets were obtained from several other institutions. During the project, the data were organized in the NOWESP Research Data Base (NRDB), for which a special data base scheme was defined that was capable of storing different types of marine data. Data products, like time series and interpolated fields, were provided to the partners for analysis (Radach et al. [1997]). After three years of project time, the feasibility of such an approach is discussed. Ways of optimizing data access and evaluation are proposed. A project-oriented Research Data Base is a useful tool because of its flexibility and proximity to the research being carried out. However, several requirements must be met to derive optimum benefits from this type of service unit. Since this task usually is carried out by a limited number of staff, an early start of project data management is recommended. To enable future projects to succeed in an analogous compilation of relevant data for their use, as performed in NOWESP, the task of organizing the data sets for any short-term project should be shared between a research data base group and a national or international data centre whose experience and software could be used. It must be ensured that only quality controlled data sets from the individual data-produ cing projects are delivered to the national data centres. It is recommended that data quality control should be performed by the originators and/or data centres before delivering any data sets to the research data base. Delivery of the (full) data sets should be checked and their quality should be approved by authorized data centres.

  15. Distributed and grid computing projects with research focus in human health.

    Science.gov (United States)

    Diomidous, Marianna; Zikos, Dimitrios

    2012-01-01

    Distributed systems and grid computing systems are used to connect several computers to obtain a higher level of performance, in order to solve a problem. During the last decade, projects use the World Wide Web to aggregate individuals' CPU power for research purposes. This paper presents the existing active large scale distributed and grid computing projects with research focus in human health. There have been found and presented 11 active projects with more than 2000 Processing Units (PUs) each. The research focus for most of them is molecular biology and, specifically on understanding or predicting protein structure through simulation, comparing proteins, genomic analysis for disease provoking genes and drug design. Though not in all cases explicitly stated, common target diseases include research to find cure against HIV, dengue, Duchene dystrophy, Parkinson's disease, various types of cancer and influenza. Other diseases include malaria, anthrax, Alzheimer's disease. The need for national initiatives and European Collaboration for larger scale projects is stressed, to raise the awareness of citizens to participate in order to create a culture of internet volunteering altruism.

  16. The SARAF Project - Soreq Applied Research Accelerator Facility

    International Nuclear Information System (INIS)

    Nagler, A.; Mardor, I.; Berkovits, D.; Piel, C.

    2004-01-01

    The relevance of particle accelerators to society, in the use of their primary and secondary beams for the analysis of physical, chemical and biological samples and for modification of properties of materials, is well recognized and documented. Nevertheless, apart of the construction of small accelerators for nuclear research in the 1960's and 70's, Israel has so far neglected this important and growing field. Furthermore, there is an urgent need in Israel for a state of the art research facility to attract and introduce students to current advanced physics techniques and technologies and to train the next generation of experimental scientists in various branches and disciplines. Therefore, Soreq NRC recently initiated the establishment of a new accelerator facility, named SARAF Soreq Applied Research Accelerator Facility. SARAF will be a continuous wave (CW), proton and deuteron RF superconducting linear accelerator with variable energy (5 - 40 MeV) and current (0.04 -2 mA). SARAF is designed to enable hands-on maintenance, which means that its beam loss will be below 10 -5 for the entire accelerator. These specifications will place SARAF in line with the next generation of accelerators world wide. Soreq expects that this fact will attract the Israeli and international research communities to use this facility extensively. Soreq NRC intends to use SARAF for basic, medical and biological research, and non-destructive testing (NDT). Another major activity will be the research and development of radio-isotopes production techniques. Given the availability of high current (up to 2 mA) protons and deuterons, a major activity will be research and development of high power density (up to 80 kW on a few cm 2 ) irradiation targets

  17. Radiation research contracts: Biological effects of small radiation doses

    Energy Technology Data Exchange (ETDEWEB)

    Hug, O [International Atomic Energy Agency, Division of Health, Safety and Waste Disposal, Vienna (Austria)

    1959-04-15

    To establish the maximum permissible radiation doses for occupational and other kinds of radiation exposure, it is necessary to know those biological effects which can be produced by very small radiation doses. This particular field of radiation biology has not yet been sufficiently explored. This holds true for possible delayed damage after occupational radiation exposure over a period of many years as well as for acute reactions of the organism to single low level exposures. We know that irradiation of less than 25 Roentgen units (r) is unlikely to produce symptoms of radiation sickness. We have, however, found indications that even smaller doses may produce certain instantaneous reactions which must not be neglected

  18. Art meets science: The Cosmopolitan Chicken Research Project.

    Science.gov (United States)

    Stinckens, A; Vereijken, A; Ons, E; Konings, P; Van As, P; Cuppens, H; Moreau, Y; Sakai, R; Aerts, J; Goddeeris, B; Buys, N; Vanmechelen, K; Cassiman, J J

    2015-01-01

    The Cosmopolitan Chicken Project is an artistic undertaking of renowned artist Koen Vanmechelen. In this project, the artist interbreeds domestic chickens from different countries aiming at the creation of a true Cosmopolitan Chicken as a symbol for global diversity. The unifying theme is the chicken and the egg, symbols that link scientific, political, philosophical and ethical issues. The Cosmopolitan Chicken Research Project is the scientific component of this artwork. Based on state of the art genomic techniques, the project studies the effect of the crossing of chickens on the genetic diversity. Also, this research is potentially applicable to the human population. The setup of the CC®P is quite different from traditional breeding experiments: starting from the crossbreed of two purebred chickens (Mechelse Koekoek x Poule de Bresse), every generation is crossed with a few animals from another breed. For 26 of these purebred and crossbred populations, genetic diversity was measured (1) under the assumption that populations were sufficiently large to maintain all informative SNP within a generation and (2) under the circumstances of the CCP breeding experiment. Under the first assumption, a steady increase in genetic diversity was witnessed over the consecutive generations, thus indeed indicating the creation of a "Cosmopolitan Chicken Genome". However, under the conditions of the CCP, which reflects the reality within the human population, diversity is seen to fluctuate within given boundaries instead of steadily increasing. A reflection on this might be that this is because, in humans, an evolutionary optimum in genetic diversity is reached. Key words.

  19. Eurotrac: a co-ordinated project for applied tropospheric research

    Energy Technology Data Exchange (ETDEWEB)

    Borrell, P [EUROTRAC International Scientific Secretariat, Garmisch-Partenkirchen (Germany)

    1996-12-31

    It was with the realisation that the scientific problems associated with regional air pollution could only be solved within the framework of an international interdisciplinary approach that in 1985 EUROTRAC, the European co-ordinated research project, was formed. Such an approach provides the scientific consensus necessary for the acceptance of regional air-pollution abatement measures by the countries affected. EUROTRAC is a EUREKA environmental project, studying the transport and chemical transformation of trace substances and pollutants in the troposphere. Three goals were specified the outset: (1) to increase the basic knowledge in atmospheric science, (2) to promote the technological development of sensitive, specific and fast response instruments for environmental research and development, and (3) to improve the scientific basis for taking future political decisions on environmental management in the European countries. Thus EUROTRAC was founded as a scientific project but had the specific intention that its results should be utilised in the formulation of policy. This presentation reviews the progress made towards each of the three goals and also indicates the proposed direction which a follow-on project is likely to take when EUROTRAC finishes at the end of 1995. (author)

  20. Eurotrac: a co-ordinated project for applied tropospheric research

    Energy Technology Data Exchange (ETDEWEB)

    Borrell, P. [EUROTRAC International Scientific Secretariat, Garmisch-Partenkirchen (Germany)

    1995-12-31

    It was with the realisation that the scientific problems associated with regional air pollution could only be solved within the framework of an international interdisciplinary approach that in 1985 EUROTRAC, the European co-ordinated research project, was formed. Such an approach provides the scientific consensus necessary for the acceptance of regional air-pollution abatement measures by the countries affected. EUROTRAC is a EUREKA environmental project, studying the transport and chemical transformation of trace substances and pollutants in the troposphere. Three goals were specified the outset: (1) to increase the basic knowledge in atmospheric science, (2) to promote the technological development of sensitive, specific and fast response instruments for environmental research and development, and (3) to improve the scientific basis for taking future political decisions on environmental management in the European countries. Thus EUROTRAC was founded as a scientific project but had the specific intention that its results should be utilised in the formulation of policy. This presentation reviews the progress made towards each of the three goals and also indicates the proposed direction which a follow-on project is likely to take when EUROTRAC finishes at the end of 1995. (author)

  1. Research on prokaryocyte expression and biological activity of the ...

    African Journals Online (AJOL)

    Jane

    ACKNOWLEDGEMENTS. Project supported by the Natural Sciences Foundation of ... (2010CB534912) and Guizhou University innovation funds of graduate .... endonuclease R. Eco R124I: over-production and biochemical properties. J. Mol.

  2. NORA project offers unique reactor research and advanced training opportunities

    International Nuclear Information System (INIS)

    1961-01-01

    An international program for reactor research and advanced training for a period of three years has been established in connection with the Norwegian critical assembly NORA. The aim of the project is to determine, through integral experiments, the basic reactor physics data for lattices moderated with light-water, heavy-water or mixtures of heavy and light water, with fuels of different sizes and spacing, three different enrichments and compositions. The objectives, programme, and facilities are described in details

  3. Advances in Biological Water-saving Research: Challenge and Perspectives

    Institute of Scientific and Technical Information of China (English)

    Lun Shan; Xiping Deng; Suiqi Zhang

    2006-01-01

    Increasing the efficiency of water use by crops continues to escalate as a topic of concern because drought is a restrictive environmental factor for crop productivity worldwide. Greater yield per unit rainfall is one of the most important challenges in water-saving agriculture. Besides water-saving by irrigation engineering and conservation tillage, a good understanding of factors limiting and/or regulating yield now provides us with an opportunity to identify and then precisely select for physiological and breeding traits that increase the efficiency of water use and drought tolerance under water-limited conditions, biological water-saving is one means of achieving this goat. A definition of biological water-saving measures is proposed which embraces improvements in water-use efficiency (WUE) and drought tolerance, by genetic improvement and physiological regulation. The preponderance of biological water-saving measures is discussed and strategies identified for working within natural resource constraints. The technology and future perspectives of biological water saving could provide not only new water-saving techniques but also a scientific base for application of water-saving irrigation and conservation tillage.

  4. Redox Biology Course Evaluation Form | Center for Cancer Research

    Science.gov (United States)

    To improve the Redox Biology (RB) course in future years, we would appreciate your feedback by completing this course evaluation. Please score the course elements as poor, fair, average, good or excellent. Please type any comments that you have in response to the questions at the bottom of the form. Remember to include your name as you wish it to appear on the certificate.

  5. Redox Biology Final Examination 2016 | Center for Cancer Research

    Science.gov (United States)

    Numerous registrants have requested a certificate upon completion of the Redox Biology (RB) course. In order to obtain a certificate, you must answer 8 of the 12 questions below correctly. In the final examination, 1 question is derived from each of the 1-hour lectures. It is highly recommended that you have a copy of each PowerPoint presentation prior to taking the

  6. The Prospects For Research In Biological Psychiatry In Nigeria ...

    African Journals Online (AJOL)

    Biological psychiatry deals with abnormalities of brain and genetic functioning and how they interact with environmental factors to underlie the genesis, manifestation, and response to treatment of mental disorders. These issues have not featured significantly in the Nigerian psychiatric scene. Hence, we are witnessing a ...

  7. Introduction to basic molecular biologic techniques for molecular imaging researches

    International Nuclear Information System (INIS)

    Kang, Joo Hyun

    2004-01-01

    Molecular imaging is a rapidly growing field due to the advances in molecular biology and imaging technologies. With the introduction of imaging reporter genes into the cell, diverse cellular processes can be monitored, quantified and imaged non-invasively in vivo. These processes include the gene expression, protein-protein interactions, signal transduction pathways, and monitoring of cells such as cancer cells, immune cells, and stem cells. In the near future, molecular imaging analysis will allow us to observe the incipience and progression of the disease. These will make us easier to give a diagnosis in the early stage of intractable diseases such as cancer, neuro-degenerative disease, and immunological disorders. Additionally, molecular imaging method will be a valuable tool for the real-time evaluation of cells in molecular biology and the basic biological studies. As newer and more powerful molecular imaging tools become available, it will be necessary to corporate clinicians, molecular biologists and biochemists for the planning, interpretation, and application of these techniques to their fullest potential. In order for such a multidisciplinary team to be effective, it is essential that a common understanding of basic biochemical and molecular biologic techniques is achieved. Basic molecular techniques for molecular imaging methods are presented in this paper

  8. Korea-China optical technology research centre project

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Cheol Jung; Lee, J M; Rhee, Y J. and others

    2001-09-01

    The main objectives of this project are to establish the internatinal collaboration basis of optical technolgies between Korean and China through the combination of the Chinese advanced fundamental technologies with the Korea industrialization and commercialization infrastructures, by ways of exchanging scientist and informations, holding joint seminars, cooperative utilization of research resources. On the ground of this establishment, the optical technologies of Korea are supposed to be leveled up to that of the world-most advanced. At the same time, for the improvement of mutual benefit and financial profit of both of the countries, technical support for the investment on the optical industries in the two countries and establishment of foundation for the venture capitals are also the purpose of this project. Because the state-of-the-arts of the Chinese technologies such as aerospace engineering, military defense technology, applications to medical treatments, laser fusion research, and so on, are known to be far above those of Korean and upto one of the most advanced in the world, it is necessary that the acquisition of these technologies, resulting in the enhancement of the levels of domestic technologies in these fields, implementation of joint research projects for technology development as well as the balanced opportunities for commercial product/sales and cooperation should be actively pursued.

  9. Korea-China Optical Technology Research Centre Project

    International Nuclear Information System (INIS)

    Kim, Cheol Jung; Rhee, Y. J.; Jung, D. Y. and others

    2004-06-01

    The main objectives of this project are to establish the international collaboration basis of optical technologies between Korea and China. The combination of the Chinese advanced fundamental technologies with the Korean industrialization and commercialization infrastructures is realized, by ways of exchanging scientists and informations, holding joint seminars, cooperative utilization of research resources. On the ground of this establishment, the optical technologies of Korea are supposed to be leveled up to those of the world-most advanced. At the same time, for the improvement of mutual benefit and financial profit of both countries, providing technical advice and suggestions to the optical industries in the two countries is an another goal of this project. The state-of-the-arts of the Chinese technologies such as aerospace engineering, military defence technology, medical technology, laser fusion research, and so on, are known to be far above those of Korean and up to one of the most advanced in the world. Thus it is thought to be necessary that the acquisition of these technologies, implementation of joint research projects for technology development as well as the balanced opportunities for commercial product/sales and cooperation should be actively pursued in order to enhance the levels of Korean technologies in these fields

  10. Korea-China optical technology research centre project

    International Nuclear Information System (INIS)

    Kim, Cheol Jung; Lee, J. M.; Rhee, Y. J. and others

    2001-09-01

    The main objectives of this project are to establish the internatinal collaboration basis of optical technolgies between Korean and China through the combination of the Chinese advanced fundamental technologies with the Korea industrialization and commercialization infrastructures, by ways of exchanging scientist and informations, holding joint seminars, cooperative utilization of research resources. On the ground of this establishment, the optical technologies of Korea are supposed to be leveled up to that of the world-most advanced. At the same time, for the improvement of mutual benefit and financial profit of both of the countries, technical support for the investment on the optical industries in the two countries and establishment of foundation for the venture capitals are also the purpose of this project. Because the state-of-the-arts of the Chinese technologies such as aerospace engineering, military defense technology, applications to medical treatments, laser fusion research, and so on, are known to be far above those of Korean and upto one of the most advanced in the world, it is necessary that the acquisition of these technologies, resulting in the enhancement of the levels of domestic technologies in these fields, implementation of joint research projects for technology development as well as the balanced opportunities for commercial product/sales and cooperation should be actively pursued

  11. Korea-China Optical Technology Research Centre Project

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Cheol Jung; Rhee, Y. J.; Jung, D. Y. and others

    2004-06-15

    The main objectives of this project are to establish the international collaboration basis of optical technologies between Korea and China. The combination of the Chinese advanced fundamental technologies with the Korean industrialization and commercialization infrastructures is realized, by ways of exchanging scientists and informations, holding joint seminars, cooperative utilization of research resources. On the ground of this establishment, the optical technologies of Korea are supposed to be leveled up to those of the world-most advanced. At the same time, for the improvement of mutual benefit and financial profit of both countries, providing technical advice and suggestions to the optical industries in the two countries is an another goal of this project. The state-of-the-arts of the Chinese technologies such as aerospace engineering, military defence technology, medical technology, laser fusion research, and so on, are known to be far above those of Korean and up to one of the most advanced in the world. Thus it is thought to be necessary that the acquisition of these technologies, implementation of joint research projects for technology development as well as the balanced opportunities for commercial product/sales and cooperation should be actively pursued in order to enhance the levels of Korean technologies in these fields.

  12. The ENTRIA project. Selected disciplinary and interdisciplinary research topics

    International Nuclear Information System (INIS)

    Roehlig, Klaus-Juergen; Hocke, Peter; Walther, Clemens

    2015-01-01

    ENTRIA (''Disposal Options for Radioactive Residues: Interdisciplinary Analyses and Development of Evaluation Principles'', www.entria.de) is a joint research project carried out by twelve departments and institutes from German universities and major research institutions and one partner from Switzerland. It is financed by the German Ministry of Education and Research (BMBF). Scientists representing natural sciences, civil engineering, philosophy, law, social and political sciences, and technology assessment carry out disciplinary and interdisciplinary research addressing three options to manage especially high-level radioactive waste: - Final disposal in deep geological formations without any arrangements for retrieval, - disposal in deep geological formations with arrangements for monitoring and retrieval, and - (prolonged) surface (or near-surface) storage. In the paper, the following selected research topics - both disciplinary and interdisciplinary - are briefly introduced in order to provide an impression of the project scope: - Surface storage, - reference concepts for emplacement in deep geological formations with retrievability and monitoring, - radiation exposure and justification of measures, - interdisciplinary perspectives on dose limits, - comparative studies on nuclear waste governance, - nuclear waste governance in Switzerland, - public involvement and the German Site Selection Act, and - citizens' jury.

  13. Nuclear safety research project (PSF). 1999 annual report

    International Nuclear Information System (INIS)

    Muehl, B.

    2000-08-01

    The reactor safety R and D work of the Karlsruhe Research Centre (FZK) has been part of the Nuclear Safety Research Project (PSF) since 1990. The present annual report summarizes the R and D results of PSF during 1999. The research tasks cover three main topics: Light Water Reactor safety, innovative systems, and studies related to the transmutation of actinides. The importance of the Light Water Reactor safety, however, has decreased during the last year in favour of the transmutation of actinides. Numerous institutes of the research centre contribute to the PSF programme, as well as several external partners. The tasks are coordinated in agreement with internal and external working groups. The contributions to this report, which are either written in German or in English, correspond to the status of early/mid 2000. (orig.) [de

  14. Thinking Big for 25 Years: Astronomy Camp Research Projects

    Science.gov (United States)

    Hooper, Eric Jon; McCarthy, D. W.; Benecchi, S. D.; Henry, T. J.; Kirkpatrick, J. D.; Kulesa, C.; Oey, M. S.; Regester, J.; Schlingman, W. M.; Camp Staff, Astronomy

    2013-01-01

    Astronomy Camp is a deep immersion educational adventure for teenagers and adults in southern Arizona that is entering its 25th year of existence. The Camp Director (McCarthy) is the winner of the 2012 AAS Education Prize. A general overview of the program is given in an accompanying contribution (McCarthy et al.). In this presentation we describe some of the research projects conducted by Astronomy Camp participants over the years. Many of the Camps contain a strong project-oriented emphasis, which reaches its pinnacle in the Advanced Camps for teenagers. High school students from around the world participate in a microcosm of the full arc of astronomy research. They plan their own projects before the start of Camp, and the staff provide a series of "key projects." Early in the Camp the students submit observing proposals to utilize time on telescopes. (The block of observing time is secured in advance by the staff.) The participants collect, reduce and analyze astronomical data with the help of staff, and they present the results to their peers on the last night of Camp, all in a span of eight days. The Camps provide research grade telescopes and instruments, in addition to amateur telescopes. Some of the Camps occur on Kitt Peak, where we use an ensemble of telescopes: the 2.3-meter (University of Arizona) with a spectrograph; the WIYN 0.9-meter; the McMath-Pierce Solar Telescope; and the 12-meter millimeter wave telescope. Additionally the Camp has one night on the 10-meter Submillimeter Telescope on Mt. Graham. Campers use these resources to study stars, galaxies, AGN, transiting planets, molecular clouds, etc. Some of the camper-initiated projects have led to very high level performances in prestigious international competitions, such as the Intel International Science and Engineering Fair. The key projects often contribute to published astronomical research (e.g., Benecchi et al. 2010, Icarus, 207, 978). Many former Campers have received Ph.D. degrees in

  15. Energy Efficient Community Development in California: Chula Vista Research Project

    Energy Technology Data Exchange (ETDEWEB)

    Gas Technology Institute

    2009-03-31

    In 2007, the U.S. Department of Energy joined the California Energy Commission in funding a project to begin to examine the technical, economic and institutional (policy and regulatory) aspects of energy-efficient community development. That research project was known as the Chula Vista Research Project for the host California community that co-sponsored the initiative. The researches proved that the strategic integration of the selected and economically viable buildings energy efficiency (EE) measures, photovoltaics (PV), distributed generation (DG), and district cooling can produce significant reductions in aggregate energy consumption, peak demand and emissions, compared to the developer/builder's proposed baseline approach. However, the central power plant emission reductions achieved through use of the EE-DG option would increase local air emissions. The electric and natural gas utility infrastructure impacts associated with the use of the EE and EE-PV options were deemed relatively insignificant while use of the EE-DG option would result in a significant reduction of necessary electric distribution facilities to serve a large-scale development project. The results of the Chula Vista project are detailed in three separate documents: (1) Energy-Efficient Community Development in California; Chula Vista Research Project report contains a detailed description of the research effort and findings. This includes the methodologies, and tools used and the analysis of the efficiency, economic and emissions impacts of alternative energy technology and community design options for two development sites. Research topics covered included: (a) Energy supply, demand, and control technologies and related strategies for structures; (b) Application of locally available renewable energy resources including solar thermal and PV technology and on-site power generation with heat recovery; (c) Integration of local energy resources into district energy systems and existing

  16. Introduction in Indonesian Social Sciences and Humanities Research Articles: How Indonesian Writers Justify Their Research Projects

    Science.gov (United States)

    Arsyad, Safnil; Wardhana, Dian Eka Chandra

    2014-01-01

    The introductory part of a research article (RA) is very important because in this section writers must argue about the importance of their research topic and project so that they can attract their readers' attention to read the whole article. This study analyzes RA introductions written by Indonesian writers in social sciences and humanities…

  17. Reflection on an interprofessional communitybased participatory research project

    Directory of Open Access Journals (Sweden)

    A Rhoda

    2016-11-01

    Full Text Available Background. A collaborative interprofessional research project that involved community members was beneficial to community development.Objective. To draw upon the experiences of academics relating to their involvement in an interprofessional community-based participatory research(CBPR project.Methods. A Delphi study was applied as a self-reflective evaluation process to reach consensus on the lessons learnt from participation in a CBPR project. Round one of the Delphi employed closed-ended questions and the responses were analysed descriptively using Microsoft Excel (USA. The second round consisted mainly of open-ended questions and responses, and was analysed qualitatively. Ethical clearance was obtained from the University of the Western Cape research committee.Results. Based on round one of the Delphi study, it became evident that recognition of the community as a unit of identity, addressing health from physical, emotional and social perspectives and formation of long-term commitments were the CBPR principles most applied. Disseminating information to all partners and facilitation of the collaborative equitable involvement of all partners in all phases of the research were the principles least applied. Themes that emerged from the second round of the Delphi included the identification of clear objectives based on the needs of the community, a shift from identification of the needs of the community to the implementation of strategies, and the creation of capacity-building opportunities for all stakeholders.Conclusion. In a reflection on the research process, the interprofessional team of academics found that the basics of CBPR should be attended to first. A focus on clear objectives, implementation strategies and capacity building is important in CBPR.

  18. Remote Imaging Projects In Research And Astrophotography With Starpals

    Science.gov (United States)

    Fischer, Audrey; Kingan, J.

    2008-05-01

    StarPals is a nascent non-profit organization with the goal of providing opportunities for international collaboration between students of all ages within space science research. We believe that by encouraging an interest in the cosmos, the one thing that is truly Universal, from a young age, students will not only further their knowledge of and interest in science but will learn valuable teamwork and life skills. The goal is to foster respect, understanding and appreciation of cultural diversity among all StarPals participants, whether students, teachers, or mentors. StarPals aims to inspire students by providing opportunities in which, more than simply visualizing themselves as research scientists, they can actually become one. The technologies of robotic telescopes, videoconferencing, and online classrooms are expanding the possibilities like never before. In honor of IYA2009, StarPals would like to encourage 400 schools to participate on a global scale in astronomy/cosmology research on various concurrent projects. We will offer in-person or online workshops and training sessions to teach the teachers. We will be seeking publication in scientific journals for some student research. For our current project, the Double Stars Challenge, students use the robotic telescopes to take a series of four images of one of 30 double stars from a list furnished by the US Naval Observatory and then use MPO Canopus software to take distance and position angle measurements. StarPals provides students with hands-on training, telescope time, and software to complete the imaging and measuring. A paper will be drafted from our research data and submitted to the Journal of Double Star Observations. The kids who participate in this project may potentially be the youngest contributors to an article in a vetted scientific journal. Kids rapidly adapt and improve their computer skills operating these telescopes and discover for themselves that science is COOL!

  19. Evaluating the High School Lunar Research Projects Program

    Science.gov (United States)

    Shaner, A. J.; Shupla, C.; Shipp, S.; Allen, J.; Kring, D. A.

    2013-01-01

    The Center for Lunar Science and Exploration (CLSE), a collaboration between the Lunar and Planetary Institute and NASA s Johnson Space Center, is one of seven member teams of the NASA Lunar Science Institute (NLSI). In addition to research and exploration activities, the CLSE team is deeply invested in education and outreach. In support of NASA s and NLSI s objective to train the next generation of scientists, CLSE s High School Lunar Research Projects program is a conduit through which high school students can actively participate in lunar science and learn about pathways into scientific careers. The objectives of the program are to enhance 1) student views of the nature of science; 2) student attitudes toward science and science careers; and 3) student knowledge of lunar science. In its first three years, approximately 168 students and 28 teachers from across the United States have participated in the program. Before beginning their research, students undertake Moon 101, a guided-inquiry activity designed to familiarize them with lunar science and exploration. Following Moon 101, and guided by a lunar scientist mentor, teams choose a research topic, ask their own research question, and design their own research approach to direct their investigation. At the conclusion of their research, teams present their results to a panel of lunar scientists. This panel selects four posters to be presented at the annual Lunar Science Forum held at NASA Ames. The top scoring team travels to the forum to present their research in person.

  20. "On the job" learning: A bioinformatics course incorporating undergraduates in actual research projects and manuscript submissions.

    Science.gov (United States)

    Smith, Jason T; Harris, Justine C; Lopez, Oscar J; Valverde, Laura; Borchert, Glen M

    2015-01-01

    The sequencing of whole genomes and the analysis of genetic information continues to fundamentally change biological and medical research. Unfortunately, the people best suited to interpret this data (biologically trained researchers) are commonly discouraged by their own perceived computational limitations. To address this, we developed a course to help alleviate this constraint. Remarkably, in addition to equipping our undergraduates with an informatic toolset, we found our course design helped prepare our students for collaborative research careers in unexpected ways. Instead of simply offering a traditional lecture- or laboratory-based course, we chose a guided inquiry method, where an instructor-selected research question is examined by students in a collaborative analysis with students contributing to experimental design, data collection, and manuscript reporting. While students learn the skills needed to conduct bioinformatic research throughout all sections of the course, importantly, students also gain experience in working as a team and develop important communication skills through working with their partner and the class as a whole, and by contributing to an original research article. Remarkably, in its first three semesters, this novel computational genetics course has generated 45 undergraduate authorships across three peer-reviewed articles. More importantly, the students that took this course acquired a positive research experience, newfound informatics technical proficiency, unprecedented familiarity with manuscript preparation, and an earned sense of achievement. Although this course deals with analyses of genetic systems, we suggest the basic concept of integrating actual research projects into a 16-week undergraduate course could be applied to numerous other research-active academic fields. © 2015 The International Union of Biochemistry and Molecular Biology.

  1. Using Biology Education Research and Qualitative Inquiry to Inform Genomic Nursing Education.

    Science.gov (United States)

    Ward, Linda D

    Decades of research in biology education show that learning genetics is difficult and reveals specific sources of learning difficulty. Little is known about how nursing students learn in this domain, although they likely encounter similar difficulties as nonnursing students. Using qualitative approaches, this study investigated challenges to learning genetics among nursing students. Findings indicate that nursing students face learning difficulties already identified among biology students, suggesting that nurse educators might benefit from biology education research.

  2. Research and investigation on medical usage of cyclotrons as a special research project

    International Nuclear Information System (INIS)

    1980-01-01

    In the National Institute of Radiological Sciences, the special research project ''Research and investigation on the medical usage of cyclotrons'' had been carried out in the three years program from fiscal 1976 to 1978. Its purpose was to establish the methods of therapy using particle beam such as fast neutrons and the methods of diagnosis using short-lived radioisotopes and positron-emitting radioisotopes. The works were conducted comprehensively in cooperation of the personnel both in and outside the NIRS. Consequently, the purpose was able to be fulfilled satisfactorily. Following on this project, a new special research project ''Research and investigation on the medical usage of particle accelerators'' was started in fiscal 1979. These results are described on the effects of the therapy, diagnostic utilizations, and the medical usage of heavy ion accelerators. (J.P.N.)

  3. Synthetic glycopeptides and glycoproteins with applications in biological research

    Directory of Open Access Journals (Sweden)

    Ulrika Westerlind

    2012-05-01

    Full Text Available Over the past few years, synthetic methods for the preparation of complex glycopeptides have been drastically improved. The need for homogenous glycopeptides and glycoproteins with defined chemical structures to study diverse biological phenomena further enhances the development of methodologies. Selected recent advances in synthesis and applications, in which glycopeptides or glycoproteins serve as tools for biological studies, are reviewed. The importance of specific antibodies directed to the glycan part, as well as the peptide backbone has been realized during the development of synthetic glycopeptide-based anti-tumor vaccines. The fine-tuning of native chemical ligation (NCL, expressed protein ligation (EPL, and chemoenzymatic glycosylation techniques have all together enabled the synthesis of functional glycoproteins. The synthesis of structurally defined, complex glycopeptides or glyco-clusters presented on natural peptide backbones, or mimics thereof, offer further possibilities to study protein-binding events.

  4. Grete Kellenberger-Gujer: Molecular biology research pioneer.

    Science.gov (United States)

    Citi, Sandra; Berg, Douglas E

    2016-01-01

    Grete Kellenberger-Gujer was a Swiss molecular biologist who pioneered fundamental studies of bacteriophage in the mid-20(th) century at the University of Geneva. Her life and career stories are reviewed here, focusing on her fundamental contributions to our early understanding of phage biology via her insightful analyses of phenomena such as the lysogenic state of a temperate phage (λ), genetic recombination, radiation's in vivo consequences, and DNA restriction-modification; on her creative personality and interactions with peers; and how her academic advancement was affected by gender, societal conditions and cultural attitudes of the time. Her story is important scientifically, putting into perspective features of the scientific community from just before the molecular biology era started through its early years, and also sociologically, in illustrating the numerous "glass ceilings" that, especially then, often hampered the advancement of creative women.

  5. 75 FR 6401 - Medical Devices Regulated by the Center for Biologics Evaluation and Research; Availability of...

    Science.gov (United States)

    2010-02-09

    ... Biologics Evaluation and Research (HFM-17), Food and Drug Administration, suite 200N, 1401 Rockville Pike... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-M-0513] Medical Devices Regulated by the Center for Biologics Evaluation and Research; Availability of Summaries...

  6. 76 FR 71045 - Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and...

    Science.gov (United States)

    2011-11-16

    ...] Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and Information... period for the notice on its report of scientific and medical literature and information concerning the... ``Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and Information...

  7. Redox Biology Course Registration Form | Center for Cancer Research

    Science.gov (United States)

    The Redox Biology class is open to all NIH/NCI fellows and staff and will be held Septhember 27 - November 8, 2016. The last day to register is: September 21, 2016. The first 100 registrants will be accepted for the class. Those who plan to participate by Video TeleConference should also register so that you can receive the speaker handouts in advance.

  8. Redox Biology Course Evaluation Form | Center for Cancer Research

    Science.gov (United States)

    To improve the Redox Biology (RB) course in future years, we would appreciate your feedback by completing this course evaluation. Please score the course elements as poor, fair, average, good or excellent. Please type any comments that you have in response to the questions at the bottom of the form. Remember to include your name as you wish it to appear on the certificate. Thank you for your feedback.

  9. The quality control for biological-shield heavy concrete construction of nuclear power project

    International Nuclear Information System (INIS)

    Sun Hongjun; Ma Xinchao

    2012-01-01

    The paper introduces the function and characteristics of biological protective heavy-concrete, and its main application scope and role in Fangjiashan nuclear power project. From the aspects of raw material selection, mixing ratio test, heavy concrete production, the paper discusses the main control points of heavy concrete construction process, points out the basic characteristics of heavy concrete construction, and put forward measures to prevent density non-uniformity during heavy concrete construction and to control slump during transportation. Results prove that reasonable construction process control can assure the engineering quality. (authors)

  10. Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC

    DEFF Research Database (Denmark)

    Becker, Juergen C.; Stang, Andreas; zur Hausen, Axel

    2018-01-01

    Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer. Its carcinogenesis may be either caused by the clonal integration of the Merkel cell polyomavirus into the host genome or by UV-induced mutations. Notably, virally-encoded oncoproteins and UV-induced mutations...... knowledge on epidemiology, biology and therapy of MCC as conclusion of the project 'Immune Modulating strategies for treatment of Merkel Cell Carcinoma', which was funded over a 5-year period by the European Commission to investigate innovative immunotherapies for MCC....

  11. Mizunami Underground Research Laboratory project. Plan for fiscal year 2017

    International Nuclear Information System (INIS)

    Ishibashi, Masayuki; Hama, Katsuhiro; Iwatsuki, Teruki; Matsui, Hiroya; Takeuchi, Ryuji; Ikeda, Koki; Mikake, Shinichiro; Iyatomi, Yosuke; Sasao, Eiji; Koide, Kaoru

    2017-10-01

    The Mizunami Underground Research Laboratory (MIU) Project is being pursued by the Japan Atomic Energy Agency (JAEA) to enhance the reliability of geological disposal technologies through investigations of the deep geological environment in the crystalline host rock (granite) at Mizunami, Gifu Prefecture, central Japan. On the occasion of the reform of the entire JAEA organization in 2014, JAEA identified three important issues on the geoscientific research program: 'Development of countermeasure technologies for reducing groundwater inflow', 'Development of modelling technologies for mass transport' and 'Development of drift backfilling technology', based on the latest results of the synthesizing research and development (R and D). The R and D on three remaining important issues has been carrying out on the MIU Project. This report summarizes the R and D activities planned for fiscal year 2017 on the basis of the MIU Master Plan updated in 2015 and Investigation Plan for the Third Medium to Long-term Research Phase. (author)

  12. Management of Service Projects in Support of Space Flight Research

    Science.gov (United States)

    Love, J.

    2009-01-01

    Goal:To provide human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration . [HRP-47051] Specific Objectives: 1) Develop capabilities, necessary countermeasures, and technologies in support of human space exploration, focusing on mitigating the highest risks to human health and performance. 2) Define and improve human spaceflight medical, environmental, and human factors standards. 3) Develop technologies that serve to reduce medical and environmental risks, to reduce human systems resource requirements (mass, volume, power, data, etc.) and to ensure effective human-system integration across exploration systems. 4) Ensure maintenance of Agency core competencies necessary to enable risk reduction in the following areas: A. Space medicine B. Physiological and behavioral effects of long duration spaceflight on the human body C. Space environmental effects, including radiation, on human health and performance D. Space "human factors" [HRP-47051]. Service projects can form integral parts of research-based project-focused programs to provide specialized functions. Traditional/classic project management methodologies and agile approaches are not mutually exclusive paradigms. Agile strategies can be combined with traditional methods and applied in the management of service projects functioning in changing environments. Creative collaborations afford a mechanism for mitigation of constrained resource limitations.

  13. Energy policy fundamentals research programme - Activities and projects in 2002

    International Nuclear Information System (INIS)

    Meier, R.; Previdoli, P.

    2003-01-01

    This annual report for the Swiss Federal Office of Energy reviews the activities and projects carried out within the Swiss Confederation's Energy Policy Fundamentals Research programme during 2002. The programme's main centres of activity are described, including projects involving the acquisition of data on indicators of selected cantonal energy saving measures, the possibility of reducing carbon dioxide emissions by influencing fuel prices, new construction instead of refurbishment of buildings, internalisation of risks involved with nuclear power and the marginal costs of intensified energy-efficiency measures. In the technology monitoring area, the results of studies concerning combined heat and power systems, heat pumps and fuel cells are reviewed. Further projects are described in the building and fuel supply areas and the influence of wind power on European peak power requirements is examined. Marketing aspects concerning the thermal use of solar energy and low energy consumption housing are discussed, as is the promotion of energy efficiency in housing and industry. Also local and regional efforts being made in the energy policy area are described. The report is rounded off with a list of the various projects mentioned in the report and appropriate contact information

  14. Research and development project report for FY 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    This report summarizes results of research and development projects administered by NEDO for FY 1996. Overview of new energy projects and twelve chapters for individual projects are provided in the report. The new energy technology development projects administered by NEDO are classified into twelve categories, i.e., Development of technologies for solar energy utilization, Development of geothermal resources, Development of technologies for exploration and utilization of geothermal energy, Development of coal energy utilization technologies, Development of coal resources, Development of energy conversion and storage technologies, Development of hydrogen, alcohol and biomass technologies, Development of other oil-alternative energy technologies, Introduction and promotion of new energy sources, International energy-promotion activities, Promotion of development and introduction, and Activities of the NEDO Information Center. To ensure energy security and actively cope with environmental problems such as by taking carbon dioxide emission control measures, NEDO has stepped up its efforts to develop new energy- and energy saving-related technologies and introduce and diffuse them. 79 figs., 37 tabs.

  15. Implementation of a Collaborative Series of Classroom-Based Undergraduate Research Experiences Spanning Chemical Biology, Biochemistry, and Neurobiology.

    Science.gov (United States)

    Kowalski, Jennifer R; Hoops, Geoffrey C; Johnson, R Jeremy

    2016-01-01

    Classroom undergraduate research experiences (CUREs) provide students access to the measurable benefits of undergraduate research experiences (UREs). Herein, we describe the implementation and assessment of a novel model for cohesive CUREs focused on central research themes involving faculty research collaboration across departments. Specifically, we implemented three collaborative CUREs spanning chemical biology, biochemistry, and neurobiology that incorporated faculty members' research interests and revolved around the central theme of visualizing biological processes like Mycobacterium tuberculosis enzyme activity and neural signaling using fluorescent molecules. Each CURE laboratory involved multiple experimental phases and culminated in novel, open-ended, and reiterative student-driven research projects. Course assessments showed CURE participation increased students' experimental design skills, attitudes and confidence about research, perceived understanding of the scientific process, and interest in science, technology, engineering, and mathematics disciplines. More than 75% of CURE students also engaged in independent scientific research projects, and faculty CURE contributors saw substantial increases in research productivity, including increased undergraduate student involvement and academic outputs. Our collaborative CUREs demonstrate the advantages of multicourse CUREs for achieving increased faculty research productivity and traditional CURE-associated student learning and attitude gains. Our collaborative CURE design represents a novel CURE model for ongoing laboratory reform that benefits both faculty and students. © 2016 J. R. Kowalski et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  16. IAEA Assistance in the development of new research reactor projects

    Energy Technology Data Exchange (ETDEWEB)

    Borio di Tigliole, Andrea; Bradley, Ed; Zhukova, Anastasia; Adelfang, Pablo [International Atomic Energy Agency, Research Reactor Section, Vienna (Austria); Shokr, Amgad [International Atomic Energy Agency, Research Reactor Safety Section, Vienna (Austria); Ridikas, Danas [International Atomic Energy Agency, Physics Section, Vienna (Austria)

    2015-08-15

    A research reactor (RR) project is a major undertaking that requires careful preparation, planning, implementation and investment in time, money, and human resources. In recent years, the interest of IAEA Member States in developing RR programmes has grown significantly, and currently, several Member States are in different stages of new RR projects. The majority of these countries are building their first RR as a key national facility for the development of their nuclear science and technology programmes, including nuclear power. In order to support Member States in such efforts, the IAEA in 2012 published the Nuclear Energy Series Report No. NP-T-5.1 on Specific Considerations and Milestones for a Research Reactor Project. To provide further support, the IAEA also published a document to assist Member States in the preparation of the bid invitation specification for the purchase of a RR. The IAEA will also continue to provide assistance for human resources development of the Member States establishing their first RR, and to facilitate sharing experience and knowledge among Member States through its programmatic activities including expert mission services, technical meetings, training courses and workshops addressing relevant technical and safety topics. This paper presents the IAEA assistance and services provided to the Member States considering new RRs, with particular emphasis on those establishing their first RR, including elaboration on the services mentioned above.

  17. Barriers and Solutions to Conducting Large International, Interdisciplinary Research Projects

    Science.gov (United States)

    Pischke, Erin C.; Knowlton, Jessie L.; Phifer, Colin C.; Gutierrez Lopez, Jose; Propato, Tamara S.; Eastmond, Amarella; de Souza, Tatiana Martins; Kuhlberg, Mark; Picasso Risso, Valentin; Veron, Santiago R.; Garcia, Carlos; Chiappe, Marta; Halvorsen, Kathleen E.

    2017-12-01

    Global environmental problems such as climate change are not bounded by national borders or scientific disciplines, and therefore require international, interdisciplinary teamwork to develop understandings of their causes and solutions. Interdisciplinary scientific work is difficult enough, but these challenges are often magnified when teams also work across national boundaries. The literature on the challenges of interdisciplinary research is extensive. However, research on international, interdisciplinary teams is nearly non-existent. Our objective is to fill this gap by reporting on results from a study of a large interdisciplinary, international National Science Foundation Partnerships for International Research and Education (NSF-PIRE) research project across the Americas. We administered a structured questionnaire to team members about challenges they faced while working together across disciplines and outside of their home countries in Argentina, Brazil, and Mexico. Analysis of the responses indicated five major types of barriers to conducting interdisciplinary, international research: integration, language, fieldwork logistics, personnel and relationships, and time commitment. We discuss the causes and recommended solutions to the most common barriers. Our findings can help other interdisciplinary, international research teams anticipate challenges, and develop effective solutions to minimize the negative impacts of these barriers to their research.

  18. Barriers and Solutions to Conducting Large International, Interdisciplinary Research Projects.

    Science.gov (United States)

    Pischke, Erin C; Knowlton, Jessie L; Phifer, Colin C; Gutierrez Lopez, Jose; Propato, Tamara S; Eastmond, Amarella; de Souza, Tatiana Martins; Kuhlberg, Mark; Picasso Risso, Valentin; Veron, Santiago R; Garcia, Carlos; Chiappe, Marta; Halvorsen, Kathleen E

    2017-12-01

    Global environmental problems such as climate change are not bounded by national borders or scientific disciplines, and therefore require international, interdisciplinary teamwork to develop understandings of their causes and solutions. Interdisciplinary scientific work is difficult enough, but these challenges are often magnified when teams also work across national boundaries. The literature on the challenges of interdisciplinary research is extensive. However, research on international, interdisciplinary teams is nearly non-existent. Our objective is to fill this gap by reporting on results from a study of a large interdisciplinary, international National Science Foundation Partnerships for International Research and Education (NSF-PIRE) research project across the Americas. We administered a structured questionnaire to team members about challenges they faced while working together across disciplines and outside of their home countries in Argentina, Brazil, and Mexico. Analysis of the responses indicated five major types of barriers to conducting interdisciplinary, international research: integration, language, fieldwork logistics, personnel and relationships, and time commitment. We discuss the causes and recommended solutions to the most common barriers. Our findings can help other interdisciplinary, international research teams anticipate challenges, and develop effective solutions to minimize the negative impacts of these barriers to their research.

  19. Setting research priorities in tobacco control: a stakeholder engagement project.

    Science.gov (United States)

    Lindson, Nicola; Richards-Doran, Dan; Heath, Laura; Hartmann-Boyce, Jamie

    2017-12-01

    The Cochrane Tobacco Addiction Group (TAG) conducts systematic reviews of the evidence for tobacco cessation and prevention interventions. In 2016 TAG conducted a priority-setting, stakeholder engagement project to identify where further research is needed in the areas of tobacco control and smoking cessation. The project comprised two surveys and a workshop. A range of stakeholders participated, including members of the public (smokers and ex-smokers), clinicians, researchers, research funders, health-care commissioners and public health organizations. The first survey phase identified unanswered research questions in the field of tobacco control. The second phase asked participants to rank these, with overall rankings calculated by combining scores across participants. The workshop allowed attendees to discuss prioritization of topics and questions in more depth. Workshop discussions were transcribed and analysed thematically, and a final voting activity at the close of the workshop allowed participants to choose topics to prioritize and to de-prioritize. A total of 304 stakeholders (researchers, health professionals, smokers and ex-smokers, guideline developers, research funders and policymakers, representing 28 countries) identified 183 unanswered research questions. These were categorized into 15 research categories. A total of 175 participants prioritized categories and questions in the second survey phase, with 'electronic cigarettes'; 'addressing inequalities'; and 'mental health and other substance abuse' prioritized as the top three categories. Forty-three stakeholders attended the workshop and discussed reasons for and against category prioritization. Prioritized research categories largely mirrored those in the survey stage, although 'treatment delivery' also emerged as a key category. Five cross-cutting themes emerged: efficacy; relative efficacy; cost effectiveness; addressing inequalities; and different types of evidence. There are many unanswered

  20. Project 'European Research Center for Air Pollution Abatement Measures'

    International Nuclear Information System (INIS)

    1985-04-01

    During the 5-7th of March 1985 the first status report of the project 'European Research Center for Air Pollution Control Measures' took place in the Nuclear Research Center, Karlsruhe. Progress reports on the following topics assessment and analysis of the impacts of airborne pollutants on forest trees; distinction from other potential causes of recent forest dieback, research into atmospheric dispersion, conversion and deposition of airborne pollutants, development and optimization of industrial-technical processes to reduce or avoid emissions and providing instruments and making recommendations to the industrial and political sectors were presented. This volume is a collection of the work reported there. 42 papers were entered separately. (orig./MG) [de