WorldWideScience

Sample records for biological research center

  1. Center for Biologics Evaluation and Research (CBER)

    Data.gov (United States)

    Federal Laboratory Consortium — CBER is the Center within FDA that regulates biological products for human use under applicable federal laws, including the Public Health Service Act and the Federal...

  2. Continuing training program in radiation protection in biological research centers

    International Nuclear Information System (INIS)

    Escudero, R.; Hidalgo, R.M.; Usera, F.; Macias, M.T.; Mirpuri, E.; Perez, J.; Sanchez, A.

    2008-01-01

    The use of ionizing radiation in biological research has many specific characteristics. A great variety of radioisotopic techniques involve unsealed radioactive sources, and their use not only carries a risk of irradiation, but also a significant risk of contamination. Moreover, a high proportion of researchers are in training and the labor mobility rate is therefore high. Furthermore, most newly incorporated personnel have little or no previous training in radiological protection, since most academic qualifications do not include training in this discipline. In a biological research center, in addition to personnel whose work is directly associated with the radioactive facility (scientific-technical personnel, operators, supervisors), there are also groups of support personnel The use of ionizing radiation in biological research has many specific characteristics. A great variety of radioisotopic techniques involve unsealed radioactive sources, and their use not only carries a risk of irradiation, but also a significant risk of contamination. Moreover, a high proportion of researchers are in training and the labor mobility rate is therefore high. Furthermore, most newly incorporated personnel have little or no previous training in radiological protection, since most academic qualifications do not include training in this discipline. In a biological research center, in addition to personnel whose work is directly associated with the radioactive facility (scientific-technical personnel, operators, supervisors), there are also groups of support personnel maintenance and instrumentation workers, cleaners, administrative personnel, etc. who are associated with the radioactive facility indirectly. These workers are affected by the work in the radioactive facility to varying degrees, and they therefore also require information and training in radiological protection tailored to their level of interaction with the installation. The aim of this study was to design a

  3. Tumor Biology and Immunology | Center for Cancer Research

    Science.gov (United States)

    Tumor Biology and Immunology The Comparative Brain Tumor Consortium is collaborating with National Center for Advanced Translational Sciences to complete whole exome sequencing on canine meningioma samples. Results will be published and made publicly available.

  4. NCI RNA Biology 2017 symposium recap | Center for Cancer Research

    Science.gov (United States)

    The recent discovery of new classes of RNAs and the demonstration that alterations in RNA metabolism underlie numerous human cancers have resulted in enormous interest among CCR investigators in RNA biology. In order to share the latest research in this exciting field, the CCR Initiative in RNA Biology held its second international symposium April 23-24, 2017, in Natcher Auditorium. Learn more...

  5. NCI RNA Biology 2017 symposium recap | Center for Cancer Research

    Science.gov (United States)

    The recent discovery of new classes of RNAs and the demonstration that alterations in RNA metabolism underlie numerous human cancers have resulted in enormous interest among CCR investigators in RNA biology. In order to share the latest research in this exciting field, the CCR Initiative in RNA Biology held its second international symposium April 23-24, 2017, in Natcher

  6. 76 FR 71045 - Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and...

    Science.gov (United States)

    2011-11-16

    ...] Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and Information... period for the notice on its report of scientific and medical literature and information concerning the... ``Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and Information...

  7. 75 FR 6401 - Medical Devices Regulated by the Center for Biologics Evaluation and Research; Availability of...

    Science.gov (United States)

    2010-02-09

    ... Biologics Evaluation and Research (HFM-17), Food and Drug Administration, suite 200N, 1401 Rockville Pike... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-M-0513] Medical Devices Regulated by the Center for Biologics Evaluation and Research; Availability of Summaries...

  8. Redox Biology Course Evaluation Form | Center for Cancer Research

    Science.gov (United States)

    To improve the Redox Biology (RB) course in future years, we would appreciate your feedback by completing this course evaluation. Please score the course elements as poor, fair, average, good or excellent. Please type any comments that you have in response to the questions at the bottom of the form. Remember to include your name as you wish it to appear on the certificate.

  9. Redox Biology Final Examination 2016 | Center for Cancer Research

    Science.gov (United States)

    Numerous registrants have requested a certificate upon completion of the Redox Biology (RB) course. In order to obtain a certificate, you must answer 8 of the 12 questions below correctly. In the final examination, 1 question is derived from each of the 1-hour lectures. It is highly recommended that you have a copy of each PowerPoint presentation prior to taking the

  10. Redox Biology Course Registration Form | Center for Cancer Research

    Science.gov (United States)

    The Redox Biology class is open to all NIH/NCI fellows and staff and will be held Septhember 27 - November 8, 2016. The last day to register is: September 21, 2016. The first 100 registrants will be accepted for the class. Those who plan to participate by Video TeleConference should also register so that you can receive the speaker handouts in advance.

  11. Redox Biology Course Evaluation Form | Center for Cancer Research

    Science.gov (United States)

    To improve the Redox Biology (RB) course in future years, we would appreciate your feedback by completing this course evaluation. Please score the course elements as poor, fair, average, good or excellent. Please type any comments that you have in response to the questions at the bottom of the form. Remember to include your name as you wish it to appear on the certificate. Thank you for your feedback.

  12. 78 FR 20924 - Center for Biologics Evaluation and Research eSubmitter Pilot Evaluation Program for...

    Science.gov (United States)

    2013-04-08

    ..., Office of Blood Research and Review, Center for Biologics Evaluation and Research (HFM-375), Food and... assist CBER in the final development and release of this electronic program for use by industry. III... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0248...

  13. 76 FR 59407 - Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and...

    Science.gov (United States)

    2011-09-26

    ...] Center for Biologics Evaluation and Research Report of Scientific and Medical Literature and Information... Administration (FDA) is announcing the availability of its report of scientific and medical literature and... Research Report of Scientific and Medical Literature and Information on Non-Standardized Allergenic...

  14. Report from the Third Annual Symposium of the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology.

    Science.gov (United States)

    Brunschweiger, Andreas

    2014-08-15

    The third Annual Symposium of the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology was held at Ringberg castle, May 21-24, 2014. At this meeting 45 scientists from Japan and Germany presented the latest results from their research spanning a broad range of topics in chemical biology and glycobiology.

  15. Centering research

    DEFF Research Database (Denmark)

    Katan, Lina Hauge; Baarts, Charlotte

    Research-based teaching has long been a distinguishing trait of higher education. Engaging students in research-like processes has been employed to great effect in learning and continues to be encouraged by educational studies. The literature on this subject reflects how ‘technical’ or ‘field......’ exercises tend to dominate the common understandings of research-based learning. Here we address a specific area of inquiry overlooked by previous studies: whether and how reading, thinking and writing indeed share the same learning potentials as the practical foundation for research-based teaching....... In the humanities and social sciences, integrated acts of reading, writing and thinking account for an obvious and substantial overlap in student and researcher practices, creating a clear opportunity for research-based teaching. Moreover, our empirical data point to reading, thinking and writing as quintessential...

  16. Space biology research development

    Science.gov (United States)

    Bonting, Sjoerd L.

    1993-01-01

    The purpose of the Search for Extraterrestrial Intelligence (SETI) Institute is to conduct and promote research related activities regarding the search for extraterrestrial life, particularly intelligent life. Such research encompasses the broad discipline of 'Life in the Universe', including all scientific and technological aspects of astronomy and the planetary sciences, chemical evolution, the origin of life, biological evolution, and cultural evolution. The primary purpose was to provide funding for the Principal Investigator to collaborate with the personnel of the SETI Institute and the NASA-Ames Research center in order to plan and develop space biology research on and in connection with Space Station Freedom; to promote cooperation with the international partners in the space station; to conduct a study on the use of biosensors in space biology research and life support system operation; and to promote space biology research through the initiation of an annual publication 'Advances in Space Biology and Medicine'.

  17. Biological Visualization, Imaging and Simulation(Bio-VIS) at NASA Ames Research Center: Developing New Software and Technology for Astronaut Training and Biology Research in Space

    Science.gov (United States)

    Smith, Jeffrey

    2003-01-01

    The Bio- Visualization, Imaging and Simulation (BioVIS) Technology Center at NASA's Ames Research Center is dedicated to developing and applying advanced visualization, computation and simulation technologies to support NASA Space Life Sciences research and the objectives of the Fundamental Biology Program. Research ranges from high resolution 3D cell imaging and structure analysis, virtual environment simulation of fine sensory-motor tasks, computational neuroscience and biophysics to biomedical/clinical applications. Computer simulation research focuses on the development of advanced computational tools for astronaut training and education. Virtual Reality (VR) and Virtual Environment (VE) simulation systems have become important training tools in many fields from flight simulation to, more recently, surgical simulation. The type and quality of training provided by these computer-based tools ranges widely, but the value of real-time VE computer simulation as a method of preparing individuals for real-world tasks is well established. Astronauts routinely use VE systems for various training tasks, including Space Shuttle landings, robot arm manipulations and extravehicular activities (space walks). Currently, there are no VE systems to train astronauts for basic and applied research experiments which are an important part of many missions. The Virtual Glovebox (VGX) is a prototype VE system for real-time physically-based simulation of the Life Sciences Glovebox where astronauts will perform many complex tasks supporting research experiments aboard the International Space Station. The VGX consists of a physical display system utilizing duel LCD projectors and circular polarization to produce a desktop-sized 3D virtual workspace. Physically-based modeling tools (Arachi Inc.) provide real-time collision detection, rigid body dynamics, physical properties and force-based controls for objects. The human-computer interface consists of two magnetic tracking devices

  18. Development of a Free-Electron Laser Center and Research in Medicine, Biology and Materials Science,

    Science.gov (United States)

    1992-05-14

    the reduced electron- larons cause localized distortions in an ionic lattice lattice coupling strength leads to molecule emission, which are... syndrome . Health Science Center at San Antonio and the University Buerger’s disease, palmar hyperhidrosis, frostbite and of Mi.imi School of Medicine, Miami

  19. Methods in Molecular Biology: Germline Stem Cells | Center for Cancer Research

    Science.gov (United States)

    The protocols in Germline Stem Cells are intended to present selected genetic, molecular, and cellular techniques used in germline stem cell research. The book is divided into two parts. Part I covers germline stem cell identification and regulation in model organisms. Part II covers current techniques used in in vitro culture and applications of germline stem cells.

  20. Tehran Nuclear Research Center

    International Nuclear Information System (INIS)

    Taherzadeh, M.

    1977-01-01

    The Tehran Nuclear Research Center was formerly managed by the University of Tehran. This Center, after its transformation to the AEOI, has now become a focal point for basic research in the area of Nuclear Energy in Iran

  1. NCI Symposium on Chromosome Biology to bring together internationally renowned experts in the fields of chromosome structure and function | Center for Cancer Research

    Science.gov (United States)

    The Center for Cancer Research’s Center of Excellence in Chromosome Biology is hosting the “Nuclear Structure, Genome Integrity and Cancer Symposium“ on November 30 - December 1, 2016 at the Natcher Conference Center, Bethesda, Maryland. Learn more ...

  2. Physical and biological studies with protons and HZE particles in a NASA supported research center in radiation health

    Science.gov (United States)

    Chatterjee, A.; Borak, T. H.

    2001-01-01

    NASA has established and supports a specialized center for research and training (NSCORT) to specifically address the potential deleterious effects of HZE particles on human health. The NSCORT in radiation health is a joint effort between Lawrence Berkeley National Laboratory (LBNL) and Colorado State University (CSU). The overall scope of research encompasses a broad range of subjects from microdosimetric studies to cellular and tissue responses to initial damage produced by highly energetic protons and heavy charged particles of the type found in galactic cosmic rays (GCR) spectrum. The objectives of the microdosimetry studies are to determine the response of Tissue Equivalent Proportional Counter (TEPC) to cosmic rays using ground based accelerators. This includes evaluation of energy loss due to the escape of high-energy delta rays and increased energy deposition due to the enhanced delta ray production in the wall of the detector. In this report major results are presented for 56Fe at 1000, 740, 600 and 400 MeV/nucleon. An assessment of DNA repair and early development of related chromosomal changes is extremely important to our overall understanding of enhanced biological effectiveness of high LET particle radiation. Results are presented with respect to the fidelity of the rejoining of double strand breaks and the implications of misrejoining. The relationship between molecular and cytogenetic measurements is presented by studying damage processing in highly heterochromatic supernumerary (correction of sypernumerary) X chromosomes and the active X-chromosome. One of the important consequences of cell's inability to handle DNA damage can be evaluated through mutation studies. Part of our goal is the assessment of potential radioprotectors to reduce the mutation yield following HZE exposures, and some promising results are presented on one compound. A second goal is the integration of DNA repair and mutation studies. Results are presented on a direct

  3. Human embryonic stem cells and good manufacturing practice: Report of a 1- day workshop held at Stem Cell Biology Research Center, Yazd, 27th April 2017

    Directory of Open Access Journals (Sweden)

    Fatemeh Akyash

    2017-09-01

    Full Text Available This report explains briefly the minutes of a 1-day workshop entitled; “human embryonic stem cells (hESCs and good manufacturing practice (GMP” held by Stem Cell Biology Research Center based in Yazd Reproductive Sciences Institute at Shahid Sadoughi University of Medical Sciences, Yazd, Iran on 27th April 2017. In this workshop, in addition to the practical sessions, Prof. Harry D. Moore from Centre for Stem Cell Biology, University of Sheffield, UK presented the challenges and the importance of the biotechnology of clinical-grade human embryonic stem cells from first derivation to robust defined culture for therapeutic applications.

  4. Human embryonic stem cells and good manufacturing practice: Report of a 1- day workshop held at Stem Cell Biology Research Center, Yazd, 27th April 2017.

    Science.gov (United States)

    Akyash, Fatemeh; Sadeghian-Nodoushan, Fatemeh; Tahajjodi, Somayyeh Sadat; Nikukar, Habib; Farashahi Yazd, Ehsan; Azimzadeh, Mostafa; D Moore, Harry; Aflatoonian, Behrouz

    2017-05-01

    This report explains briefly the minutes of a 1-day workshop entitled; "human embryonic stem cells (hESCs) and good manufacturing practice (GMP)" held by Stem Cell Biology Research Center based in Yazd Reproductive Sciences Institute at Shahid Sadoughi University of Medical Sciences, Yazd, Iran on 27 th April 2017. In this workshop, in addition to the practical sessions, Prof. Harry D. Moore from Centre for Stem Cell Biology, University of Sheffield, UK presented the challenges and the importance of the biotechnology of clinical-grade human embryonic stem cells from first derivation to robust defined culture for therapeutic applications.

  5. Water Resources Research Center

    Science.gov (United States)

    Untitled Document  Search Welcome to the University of Hawai'i at Manoa Water Resources Research Center At WRRC we concentrate on addressing the unique water and wastewater management problems and issues elsewhere by researching water-related issues distinctive to these areas. We are Hawaii's link in a network

  6. Senior Computational Scientist | Center for Cancer Research

    Science.gov (United States)

    The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR). The Cancer & Inflammation Program (CIP),

  7. Research Associate | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR). KEY ROLES/RESPONSIBILITIES - Research Associate III Dr. Zbigniew Dauter is the head investigator of the Synchrotron Radiation Research Section (SRRS) of CCR’s Macromolecular Crystallography Laboratory. The Synchrotron Radiation Research Section is located at Argonne National Laboratory, Argonne, Illinois; this is the site of the largest U.S. synchrotron facility. The SRRS uses X-ray diffraction technique to solve crystal structures of various proteins and nucleic acids of biological and medical relevance. The section is also specializing in analyzing crystal structures at extremely high resolution and accuracy and in developing methods of effective diffraction data collection and in using weak anomalous dispersion effects to solve structures of macromolecules. The areas of expertise are: Structural and molecular biology Macromolecular crystallography Diffraction data collection Dr. Dauter requires research support in these areas, and the individual will engage in the purification and preparation of samples, crystallize proteins using various techniques, and derivatize them with heavy atoms/anomalous scatterers, and establish conditions for cryogenic freezing. Individual will also participate in diffraction data collection at the Advanced Photon Source. In addition, the candidate will perform spectroscopic and chromatographic analyses of protein and nucleic acid samples in the context of their purity, oligomeric state and photophysical properties.

  8. PAC research in biology

    Energy Technology Data Exchange (ETDEWEB)

    Chain, C. Y., E-mail: yamil@fisica.unlp.edu.ar [Universidad Nacional de La Plata, IFLP (Argentina); Ceolin, M. [Instituto de Investigaciones Fisicoquimicas Teoricas y Aplicadas, Dto de Quimica, Fac. Cs. Exactas, UNLP (Argentina); Pasquevich, A. F. [Universidad Nacional de La Plata, IFLP (Argentina)

    2008-01-15

    In this paper possible applications of the Perturbed Angular Correlations (PAC) technique in Biology are considered. Previous PAC experiments in biology are globally analyzed. All the work that appears in the literature has been grouped in a few research lines, just to make the analysis and discussion easy. The commonly used radioactive probes are listed and the experimental difficulties are analyzed. We also report applications of {sup 181}Hf and {sup 111}In isotopes in life sciences other than their use in PAC. The possibility of extending these studies using the PAC technique is discussed.

  9. Illinois Accelerator Research Center

    Science.gov (United States)

    Kroc, Thomas K.; Cooper, Charlie A.

    The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and industrialization of particle accelerator technology. In addition to facilitating access to available existing Fermi infrastructure, the IARC Campus has a dedicated 36,000 ft2 Heavy Assembly Building (HAB) with all the infrastructure needed to develop, commission and operate new accelerators. Connected to the HAB is a 47,000 ft2 Office, Technology and Engineering (OTE) building, paid for by the state, that has office, meeting, and light technical space. The OTE building, which contains the Accelerator Physics Center, and nearby Accelerator and Technical divisions provide IARC collaborators with unique access to world class expertise in a wide array of accelerator technologies. At IARC scientists and engineers from Fermilab and academia work side by side with industrial partners to develop breakthroughs in accelerator science and translate them into applications for the nation's health, wealth and security.

  10. A Comparative Study of a Research-Oriented High School Advanced Biology Class and a Conventional Textbook-Centered Class.

    Science.gov (United States)

    Smith, Alva Nelson

    Two instructional methods were identified and compared to determine if any significant differences could be noted on three criterion measures. Measurements were conducted in the areas of achievement in biology, science attitudes, and critical thinking ability. Student ability was measured using pre-tests and the Scholastic Aptitude Test. Students…

  11. The DESY Research Center

    International Nuclear Information System (INIS)

    Waloschek, P.

    1988-01-01

    On November 12, 1964, the 6 GeV electrons synchrotron and the associated utility facilities were dedicated for regular operation. Since that date, the DESY Research Center, the German Electron Synchrotron in Hamburg, has offered to scientists from all over the world unique facilities in which to study the smallest constituents of matter. At present, some 580 physicists participate in DESY's research work on particle physics and high energy physics. Most of them are university teachers, a great many come from abroad. Their home institutions make considerable contributions to setting up the measuring equipment. Another 500 physicists annually make use of the extensive synchrotron radiation facilities available at DESY. DESY is one of the thirteen national research laboratories in the Federal Republic of Germany; its annual government grants for operation and personnel (1300 staff members in 1988) amount to some DM 150 million. In addition, some DM 950 million will be invested into the construction of the new HERA facility between 1984 and 1990, of which 15% will be contributed by foreign institutions. The ordinary budget of DESY is paid 90% by the German Federal Ministry for Research and Technology (BMFT) and 10% by the city of Hamburg. (orig.)

  12. Proceedings of the Edgewood Chemical Biological Center In-House Laboratory Independent Research and Surface Science Initiative Programs FY12

    Science.gov (United States)

    2012-01-01

    toxic chemicals, biological pathogens and fatigue , which can significantly compromise their health and cognitive abilities to perform complex...using piezoelectric material ( PZT ) so that it would be self-actuated and output read as a function of frequency shift. Theoretical analyses were...each design and compare real results with computer-generated, theoretical models. We designed our cantilever using piezoelectric material ( PZT ) so that

  13. Center for Prostate Disease Research

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Prostate Disease Research is the only free-standing prostate cancer research center in the U.S. This 20,000 square foot state-of-the-art basic science...

  14. Center for Rehabilitation Sciences Research

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Rehabilitation Sciences Research (CRSR) was established as a research organization to promote successful return to duty and community reintegration of...

  15. Production and Distribution Research Center

    Science.gov (United States)

    1986-05-01

    Steel, Coca Cola , Standard Oil of Ohio, and Martin Marietta have been involved in joint research with members of the Center. The number of Faculty...permitted the establishment of the Center and supports its continuing development. The Center has also received research sponsorship from the Joint...published relating to results developed within the PDRC under Offce of Naval Research sponsorship . These reports are listed in Appendix A. Many of these

  16. UC Merced Center for Computational Biology Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Colvin, Michael; Watanabe, Masakatsu

    2010-11-30

    Final report for the UC Merced Center for Computational Biology. The Center for Computational Biology (CCB) was established to support multidisciplinary scientific research and academic programs in computational biology at the new University of California campus in Merced. In 2003, the growing gap between biology research and education was documented in a report from the National Academy of Sciences, Bio2010 Transforming Undergraduate Education for Future Research Biologists. We believed that a new type of biological sciences undergraduate and graduate programs that emphasized biological concepts and considered biology as an information science would have a dramatic impact in enabling the transformation of biology. UC Merced as newest UC campus and the first new U.S. research university of the 21st century was ideally suited to adopt an alternate strategy - to create a new Biological Sciences majors and graduate group that incorporated the strong computational and mathematical vision articulated in the Bio2010 report. CCB aimed to leverage this strong commitment at UC Merced to develop a new educational program based on the principle of biology as a quantitative, model-driven science. Also we expected that the center would be enable the dissemination of computational biology course materials to other university and feeder institutions, and foster research projects that exemplify a mathematical and computations-based approach to the life sciences. As this report describes, the CCB has been successful in achieving these goals, and multidisciplinary computational biology is now an integral part of UC Merced undergraduate, graduate and research programs in the life sciences. The CCB began in fall 2004 with the aid of an award from U.S. Department of Energy (DOE), under its Genomes to Life program of support for the development of research and educational infrastructure in the modern biological sciences. This report to DOE describes the research and academic programs

  17. The Adirondack research center

    Science.gov (United States)

    Francis M. Rushmore

    1957-01-01

    Some of the first forest research done in North America was done in that lake-spangled land of forests and mountains in upper New York State that we know as the Adirondacks. The very name Adirondacks smacks of forest. The big Webster dictionary says that Adirondacks comes from a Mohawk Indian word, Hatirongtaks, which means literally, "they eat trees."

  18. Transportation Research & Analysis Computing Center

    Data.gov (United States)

    Federal Laboratory Consortium — The technical objectives of the TRACC project included the establishment of a high performance computing center for use by USDOT research teams, including those from...

  19. Tumor Biology and Microenvironment Research

    Science.gov (United States)

    Part of NCI's Division of Cancer Biology's research portfolio, research in this area seeks to understand the role of tumor cells and the tumor microenvironment (TME) in driving cancer initiation, progression, maintenance and recurrence.

  20. Research and technology, 1991. Langley Research Center

    Science.gov (United States)

    1992-01-01

    The mission of the NASA Langley Research Center is to increase the knowledge and capability of the United States in a full range of aeronautics disciplines and in selected space disciplines. This mission will be accomplished by performing innovative research relevant to national needs and Agency goals, transferring technology to users in a timely manner, and providing development support to other United States Government agencies, industry, and other NASA centers. Highlights are given of the major accomplishments and applications that have been made during the past year. The highlights illustrate both the broad range of the research and technology (R&T) activities at NASA Langley Research Center and the contributions of this work toward maintaining United States leadership in aeronautics and space research.

  1. SIMS applications in biological research

    International Nuclear Information System (INIS)

    Prince, K.E.; Burke, P.T.; Kelly, I.J.

    2000-01-01

    Full text: SIMS has been utilised as a tool for biological research since the early 1970's. SIMS' abilities in isotopic detection with high sensitivity, imaging capabilities at a subcellular level, and the possibility of molecular imaging have been the main areas of interest for biological development. However, whilst hundreds of instruments are available in industrial and university laboratories for semiconductor and materials analysis, only a handful successfully perform biological research. For this reason there is generally a lack of awareness of SIMS by the biological community. Biological SIMS analysis requires a working knowledge of both biology and SIMS. Sample preparation is a critical and time consuming prerequisite for any successful biological SIMS study. In addition, for quantification to be possible a homogeneous, matrix matched standard must be available. Once these difficulties are more widely understood and overcome there will be a greater motivation for the biological community to embrace SIMS as a unique tool in their research. This paper provides an overview of some of the more successful biological SIMS application areas internationally, and summarises the types of biological SIMS requests received by ANSTO

  2. Colorado Learning Disabilities Research Center.

    Science.gov (United States)

    DeFries, J. C.; And Others

    1997-01-01

    Results obtained from the center's six research projects are reviewed, including research on psychometric assessment of twins with reading disabilities, reading and language processes, attention deficit-hyperactivity disorder and executive functions, linkage analysis and physical mapping, computer-based remediation of reading disabilities, and…

  3. Biological Defense Research Program

    Science.gov (United States)

    1989-04-01

    difference between life and death. Some recent examples are: BDRP developed VEE vaccine used in Central America, Mexico , and Texas (1969- 1971.) and Rift...Complex, is adn area owned by the Bureau of Land Management, which is available for grazina, and with specific permission, for use by DPG. 2.3...2.01 A Large European Laboratory, 1944-1950 50.00 Tuberculosis Laboratory 4 Technicians, Canada, 1947-1954 19.00 Research Institutes, 1930-1950 4.10

  4. Scientific activities 1980 Nuclear Research Center ''Democritos''

    International Nuclear Information System (INIS)

    1982-01-01

    The scientific activities and achievements of the Nuclear Research Center Democritos for the year 1980 are presented in the form of a list of 76 projects giving title, objectives, responsible of each project, developed activities and the pertaining lists of publications. The 16 chapters of this work cover the activities of the main Divisions of the Democritos NRC: Electronics, Biology, Physics, Chemistry, Health Physics, Reactor, Scientific Directorate, Radioisotopes, Environmental Radioactivity, Soil Science, Computer Center, Uranium Exploration, Medical Service, Technological Applications, Radioimmunoassay and Training. (N.C.)

  5. Engineer Research and Development Center's Materials Testing Center (MTC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Engineer Research and Development Center's Materials Testing Center (MTC) is committed to quality testing and inspection services that are delivered on time and...

  6. Introduction | Center for Cancer Research

    Science.gov (United States)

    Introduction In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Jeffrey Strathern and Bob Wiltrout established a partnership user program (PUP) with the Argonne National Laboratory Photon Source in October 2008.

  7. Ames Research Center Research and Technology 2000

    Science.gov (United States)

    2002-01-01

    This report highlights the challenging work accomplished during fiscal year 2000 by Ames research scientists,engineers, and technologists. It discusses research and technologies that enable the Information Age, that expand the frontiers of knowledge for aeronautics and space, and that help to maintain U.S. leadership in aeronautics and space research and technology development. The accomplishments are grouped into four categories based on four of NASA's Strategic Enterprises: Aerospace Technology, Space Science, Biological and Physical Research, and Earth Science. The primary purpose of this report is to communicate knowledge-to inform our stakeholders, customer, and partners, and the people of the United States about the scope and diversity of Ames' mission,the nature of Ames' research and technolog) activities,and the stimulating challenges ahead. The accomplishments cited illustrate the contributions that Ames is willing to improve the quality of life for our citizens and the economic position of the United States in the world marketplace.

  8. Flow Cytometry Technician | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR). KEY ROLES/RESPONSIBILITIES The Flow Cytometry Core (Flow Core) of the Cancer and Inflammation Program (CIP) is a service core which supports the research efforts of the CCR by providing expertise in the field of flow cytometry (using analyzers and sorters) with the goal of gaining a more thorough understanding of the biology of cancer and cancer cells. The Flow Core provides service to 12-15 CIP laboratories and more than 22 non-CIP laboratories. Flow core staff provide technical advice on the experimental design of applications, which include immunological phenotyping, cell function assays, and cell cycle analysis. Work is performed per customer requirements, and no independent research is involved. The Flow Cytometry Technician will be responsible for: Monitor performance of and maintain high dimensional flow cytometer analyzers and cell sorters Operate high dimensional flow cytometer analyzers and cell sorters Monitoring lab supply levels and order lab supplies, perform various record keeping responsibilities Assist in the training of scientific end users on the use of flow cytometry in their research, as well as how to operate and troubleshoot the bench-top analyzer instruments Experience with sterile technique and tissue culture

  9. Research Associate | Center for Cancer Research

    Science.gov (United States)

    The Basic Science Program (BSP) at the Frederick National Laboratory for Cancer Research (FNLCR) pursues independent, multidisciplinary research programs in basic or applied molecular biology, immunology, retrovirology, cancer biology or human genetics. As part of the BSP, the Microbiome and Genetics Core (the Core) characterizes microbiomes by next-generation sequencing to determine their composition and variation, as influenced by immune, genetic, and host health factors. The Core provides support across a spectrum of processes, from nucleic acid isolation through bioinformatics and statistical analysis. KEY ROLES/RESPONSIBILITIES The Research Associate II will provide support in the areas of automated isolation, preparation, PCR and sequencing of DNA on next generation platforms (Illumina MiSeq and NextSeq). An opportunity exists to join the Core’s team of highly trained experimentalists and bioinformaticians working to characterize microbiome samples. The following represent requirements of the position: A minimum of five (5) years related of biomedical experience. Experience with high-throughput nucleic acid (DNA/RNA) extraction. Experience in performing PCR amplification (including quantitative real-time PCR). Experience or familiarity with robotic liquid handling protocols (especially on the Eppendorf epMotion 5073 or 5075 platforms). Experience in operating and maintaining benchtop Illumina sequencers (MiSeq and NextSeq). Ability to evaluate experimental quality and to troubleshoot molecular biology protocols. Experience with sample tracking, inventory management and biobanking. Ability to operate and communicate effectively in a team-oriented work environment.

  10. History of the department of virology and molecular and biological methods of investigation of pediatric research and clinical center for infectious diseases

    Directory of Open Access Journals (Sweden)

    E. A. Murina

    2017-01-01

    Full Text Available The article deals with the history of formation of virology laboratory since 1963 after the resolution of the Academy of Medical Sciences of the USSR and the Ministry of Public Health on the expansion of virology investigation in the USSR.The results of the research work on studying various infections in children, developing new modified approaches to etiological express-diagnostics of the diseases, including those introduced into practice of the laboratory and regional medical centers are generalized. The laboratory got the name of the Department of Etiological Diagnostics Methods due to the basic direction of the research work. The primary goal of the department is to develop the methods and diagnostic algorithms for definite verification of infectious forms and the prognosis of the development of pathological process that allows determining the direction of further therapeutic approach to improve the disease outcome. In 2008 the Department of Etiological Diagnostics Methods began its «golden age» characterized by cardinal re-equipment and strengthening of the staff. There appeared the devices of expert class which completely replaced the manual testing process, the work connected with interpretation of serous meningitis outbreaks in Russia and the near abroad became more active.Now the department is a hi-technology scientific and practical center on studying viral and invasive forms of diseases with a priority direction of further innovations in laboratory diagnostics. 

  11. Evolutionary Biology Research in India

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 10. Evolutionary Biology Research in India. Information and Announcements Volume 5 Issue 10 October 2000 pp 102-104. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/005/10/0102-0104 ...

  12. Statistical Analysis of Research Data | Center for Cancer Research

    Science.gov (United States)

    Recent advances in cancer biology have resulted in the need for increased statistical analysis of research data. The Statistical Analysis of Research Data (SARD) course will be held on April 5-6, 2018 from 9 a.m.-5 p.m. at the National Institutes of Health's Natcher Conference Center, Balcony C on the Bethesda Campus. SARD is designed to provide an overview on the general principles of statistical analysis of research data.  The first day will feature univariate data analysis, including descriptive statistics, probability distributions, one- and two-sample inferential statistics.

  13. [Biological research and security institutes].

    Science.gov (United States)

    Darsie, G; Falczuk, A J; Bergmann, I E

    2006-04-01

    The threat of using biological material for ago-bioterrorist ends has risen in recent years, which means that research and diagnostic laboratories, biological agent banks and other institutions authorised to carry out scientific activities have had to implement biosafety and biosecurity measures to counter the threat, while carrying out activities to help prevent and monitor the accidental or intentional introduction of exotic animal diseases. This article briefly sets outthe basic components of biosafety and biosecurity, as well as recommendations on organisational strategies to consider in laboratories that support agro-bioterrorist surveillance and prevention programs.

  14. NASA Airline Operations Research Center

    Science.gov (United States)

    Mogford, Richard H.

    2016-01-01

    This is a PowerPoint presentation NASA airline operations center (AOC) research. It includes information on using IBM Watson in the AOC. It also reviews a dispatcher decision support tool call the Flight Awareness Collaboration Tool (FACT). FACT gathers information about winter weather onto one screen and includes predictive abilities. It should prove to be useful for airline dispatchers and airport personnel when they manage winter storms and their effect on air traffic. This material is very similar to other previously approved presentations with the same title.

  15. Development trend of radiation biology research-systems radiation biology

    International Nuclear Information System (INIS)

    Min Rui

    2010-01-01

    Radiation biology research has past 80 years. We have known much more about fundamentals, processes and results of biology effects induced by radiation and various factors that influence biology effects wide and deep, however many old and new scientific problems occurring in the field of radiation biology research remain to be illustrated. To explore and figure these scientific problems need systemic concept, methods and multi dimension view on the base of considerations of complexity of biology system, diversity of biology response, temporal and spatial process of biological effects during occurrence, and complex feed back network of biological regulations. (authors)

  16. Unique life sciences research facilities at NASA Ames Research Center

    Science.gov (United States)

    Mulenburg, G. M.; Vasques, M.; Caldwell, W. F.; Tucker, J.

    1994-01-01

    The Life Science Division at NASA's Ames Research Center has a suite of specialized facilities that enable scientists to study the effects of gravity on living systems. This paper describes some of these facilities and their use in research. Seven centrifuges, each with its own unique abilities, allow testing of a variety of parameters on test subjects ranging from single cells through hardware to humans. The Vestibular Research Facility allows the study of both centrifugation and linear acceleration on animals and humans. The Biocomputation Center uses computers for 3D reconstruction of physiological systems, and interactive research tools for virtual reality modeling. Psycophysiological, cardiovascular, exercise physiology, and biomechanical studies are conducted in the 12 bed Human Research Facility and samples are analyzed in the certified Central Clinical Laboratory and other laboratories at Ames. Human bedrest, water immersion and lower body negative pressure equipment are also available to study physiological changes associated with weightlessness. These and other weightlessness models are used in specialized laboratories for the study of basic physiological mechanisms, metabolism and cell biology. Visual-motor performance, perception, and adaptation are studied using ground-based models as well as short term weightlessness experiments (parabolic flights). The unique combination of Life Science research facilities, laboratories, and equipment at Ames Research Center are described in detail in relation to their research contributions.

  17. Electron Microscopy-Data Analysis Specialist | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for

  18. CSMB | Center For Structural Molecular Biology

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Structural Molecular Biologyat ORNL is dedicated to developing instrumentation and methods for determining the 3-dimensional structures of proteins,...

  19. NDE research at NASA Langley Research Center

    International Nuclear Information System (INIS)

    Heyman, J.S.

    1989-01-01

    The Nondestructive Measurement Science Branch at NASA Langley is the Agency's lead Center for NDE research. The focus of the laboratory is to improve the science base for NDE, evolve a more quantitative, interpretable technology to insure safety and reliability, and transfer that technology to the commercial sector. To address the broad needs of the Agency, the program has developed expertise in many areas, some of which are in ultrasonics, nonlinear acoustics, nano and microstructure characterization, thermal NDE, x-ray tomography, optical fiber sensors, magnetic probing, process monitoring sensors, and image/signal processing. The authors laboratory has recently dedicated its new 20,000 square foot research facility bringing the lab space to 30,000 square feet. The new facility includes a high bay for the x-ray CAT scanner, a revolutionary new concept in materials measurement. The CAT scanner is called QUEST, for quantitative experimental stress tomography lab. This system combines for the first time a microfocus x-ray source and detector with a fatigue load frame. Three dimensional imaging of density/geometry of the tested sample is thus possible during tension/compression loading. This system provides the first 3-D view of crack initiation, crack growth, phase transformation, bonded surface failure, creep-all with a density sensitivity of 0.1% and a resolution of about 25 microns (detectability of about 1 micron)

  20. Electron Microscopist | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR). The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and genetics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR). CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES/RESPONSIBILITIES - THIS POSITION IS CONTINGENT UPON FUNDING APPROVAL The Electron Microscopist will: Operate ultramicrotomes (Leica) and other instrumentation related to the preparation of embedded samples for EM (TEM and SEM) Operate TEM microscopes, (specifically Hitachi, FEI T20 and FEI T12) as well as SEM microscopes (Hitachi); task will include loading samples, screening, and performing data collection for a variety of samples: from cells to proteins Manage maintenance for the TEM and SEM microscopes Provide technical advice to investigators on sample preparation and data collection

  1. Review of domestic radiation biology research

    International Nuclear Information System (INIS)

    Zheng Chun; Song Lingli; Ai Zihui

    2011-01-01

    Radiation biology research in China during the past ten years are reviewed. It should be noticed that radiation-biology should focus on microdosimetry, microbeam application, and radiation biological mechanism. (authors)

  2. National Biological Service Research Supports Watershed Planning

    Science.gov (United States)

    Snyder, Craig D.

    1996-01-01

    The National Biological Service's Leetown Science Center is investigating how human impacts on watershed, riparian, and in-stream habitats affect fish communities. The research will provide the basis for a Ridge and Valley model that will allow resource managers to accurately predict and effectively mitigate human impacts on water quality. The study takes place in the Opequon Creek drainage basin of West Virginia. A fourth-order tributary of the Potomac, the basin falls within the Ridge and Valley. The study will identify biological components sensitive to land use patterns and the condition of the riparian zone; the effect of stream size, location, and other characteristics on fish communities; the extent to which remote sensing can reliable measure the riparian zone; and the relationship between the rate of landscape change and the structure of fish communities.

  3. National Rehabilitation Hospital Assistive Technology Research Center

    Science.gov (United States)

    1995-10-01

    Shoulder-Arm Orthoses Several years ago, the Rehabilitation Engineering Research Center (RERC) on Rehabilitation Robotics in Delaware1 identified a... exoskeletal applications for persons with disabilities. 2. Create a center of expertise in rehabilitation technology transfer that benefits persons with...AD COOPERATIVE AGREEMENT NUMBER: DAMD17-94-V-4036 TITLE: National Rehabilitation Hospital Assistive Technology- Research Center PRINCIPAL

  4. Current research and development at the Nuclear Research Center Karlsruhe

    International Nuclear Information System (INIS)

    Kuesters, H.

    1982-01-01

    The Nuclear Research Center Karlsruhe (KfK) is funded to 90% by the Federal Republic of Germany and to 10% by the State of Baden-Wuerttemberg. Since its foundation in 1956 the main objective of the Center is research and development (R and D) in the aera of the nuclear technology and about 2/3 of the research capacity is now devoted to this field. Since 1960 a major activity of KfK is R and D work for the design of fast breeder reactors, including material research, physics, and safety investigations; a prototype of 300 MWe is under construction now in the lower Rhine Valley. For enrichment of 235 U fissile material KfK developed the separation nozzle process; its technical application is realized within an international contract between the Federal Republic of Germany and Brazil. Within the frame of the European Programme on fusion technology KfK develops and tests superconducting magnets for toroidal fusion systems; a smaller activity deals with research on inertial confinement fusion. A broad research programme is carried through for safety investigations of nuclear installations, especially for PWRs; this activity is supplemented by research and development in the field of nuclear materials' safeguards. Development of fast reactors has to initiate research for the reprocessing of spent fuel and waste disposal. In the pilot plant WAK spent fuel from LKWs is reprocessed; research especially tries e.g. to improve the PUREX-process by electrochemical means, vitrification of high active waste is another main activity. First studies are being performed now to clarify the necessary development for reprocessing fast reactor fuel. About 1/3 of the research capacity of KfK deals with fundamental research in nuclear physics, solid state physics, biology and studies on the impact of technology on environment. Promising new technologies as e.g. the replacement of gasoline by hydrogen cells as vehicle propulsion are investigated. (orig.)

  5. NASA's engineering research centers and interdisciplinary education

    Science.gov (United States)

    Johnston, Gordon I.

    1990-01-01

    A new program of interactive education between NASA and the academic community aims to improve research and education, provide long-term, stable funding, and support cross-disciplinary and multi-disciplinary research. The mission of NASA's Office of Aeronautics, Exploration and Technology (OAET) is discussed and it is pointed out that the OAET conducts about 10 percent of its total R&D program at U.S. universities. Other NASA university-based programs are listed including the Office of Commercial Programs Centers for the Commercial Development of Space (CCDS) and the National Space Grant program. The importance of university space engineering centers and the selection of the nine current centers are discussed. A detailed composite description is provided of the University Space Engineering Research Centers. Other specialized centers are described such as the Center for Space Construction, the Mars Mission Research Center, and the Center for Intelligent Robotic Systems for Space Exploration. Approaches to educational outreach are discussed.

  6. Staff Scientist - RNA Bioinformatics | Center for Cancer Research

    Science.gov (United States)

    The newly established RNA Biology Laboratory (RBL) at the Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH) in Frederick, Maryland is recruiting a Staff Scientist with strong expertise in RNA bioinformatics to join the Intramural Research Program’s mission of high impact, high reward science. The RBL is the equivalent of an

  7. Biological Research for Radiation Protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Kug Chan; Jung, Il Lae; Choi, Yong Ho; Kim, Jin Sik; Moon, Myung Sook; Byun, Hee Sun; Phyo, Ki Heon; Kim, Sung Keun

    2005-04-01

    The work scope of 'Biological Research for the Radiation Protection' had contained the research about ornithine decarboxylase and its controlling proteins, thioredoxin, peroxiredoxin, S-adenosymethionine decarboxylase, and glutamate decarboxylase 67KD effect on the cell death triggered ionizing radiation and H 2 O 2 (toxic agents). In this study, to elucidate the role of these proteins in the ionizing radiation (or H 2 O 2 )-induced apoptotic cell death, we utilized sensesed (or antisensed) cells, which overexpress (or down-regulate) RNAs associated with these proteins biosynthesis, and investigated the effects of these genes on the cytotoxicity caused by ionizing radiation and H 2 O 2 (or paraquat). We also investigated whether genisteine(or thiamine) may enhance the cytotoxic efficacy of tumor cells caused by ionizing radiation (may enhance the preventing effect radiation or paraquat-induced damage) because such compounds are able to potentiate the cell-killing or cell protecting effects. Based on the above result, we suggest that the express regulation of theses genes have potentially importance for sensitizing the efficiency of radiation therapy of cancer or for protecting the radiation-induced damage of normal cells

  8. Biological research for radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Kim, In Gyu; Kim, Kug Chan; Shim, Hae Won; Oh, Tae Jeong; Park, Seon Young; Lee, Kang Suk

    2000-04-01

    The work scope of Biological research for the radiation protection had contained the search of biological microanalytic methods for assessing the health effect by {gamma}-radiation and toxic agents, the standardization of human T-lymphocyte cell culture and polymerase chain reaction, T-cell clonal assay, and the quantification of mutation frequency in the hypoxanthine (guanine) phosphoribosyl transferase (HPRT) gene locus by single exposure or combined exposure. Especially, the polymerase chain reaction methods using reverse transcriptase has been developed to analyze the mutant gene induced by {gamma}-radiation and chemical (pentachlorophenol) agent exposure, and to investigate the point mutations in the HPRT gene locus of T-lymphocytes. The HPRT T-cell clonal assay revealed that it could not differentiate {gamma}-irradiation from pentachlorophenol, because the frequency of somatic mutations induced by both damaging agents increased in a dose-dependent manner. The analysis of DNA sequence alterations of HPRT mutant clones clearly showed that both damaging agents induced different mutational spectra in the HPRT locus of T-cells. The large deletions, which account for 75 percent of the analyzed mutants, are characteristic mutations induced by {gamma}-irradiation. By contrast, point mutations such as base substitutions and insertion, come up to 97 percent in the case of pentachlorophenol-treated cells. The point mutation frequencies at 190 base pair and 444 base pair positions are 3-6 folds as high as in those at other mutation positions. It may be that these mutation sites are hot spots induced by pentachlorophenol. These results suggest that the HPRT mutation spectrum can be used as a potential bio marker for assessing a specific environmental risk. (author)

  9. Biological research for radiation protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Kug Chan; Shim, Hae Won; Oh, Tae Jeong; Park, Seon Young; Lee, Kang Suk

    2000-04-01

    The work scope of Biological research for the radiation protection had contained the search of biological microanalytic methods for assessing the health effect by γ-radiation and toxic agents, the standardization of human T-lymphocyte cell culture and polymerase chain reaction, T-cell clonal assay, and the quantification of mutation frequency in the hypoxanthine (guanine) phosphoribosyl transferase (HPRT) gene locus by single exposure or combined exposure. Especially, the polymerase chain reaction methods using reverse transcriptase has been developed to analyze the mutant gene induced by γ-radiation and chemical (pentachlorophenol) agent exposure, and to investigate the point mutations in the HPRT gene locus of T-lymphocytes. The HPRT T-cell clonal assay revealed that it could not differentiate γ-irradiation from pentachlorophenol, because the frequency of somatic mutations induced by both damaging agents increased in a dose-dependent manner. The analysis of DNA sequence alterations of HPRT mutant clones clearly showed that both damaging agents induced different mutational spectra in the HPRT locus of T-cells. The large deletions, which account for 75 percent of the analyzed mutants, are characteristic mutations induced by γ-irradiation. By contrast, point mutations such as base substitutions and insertion, come up to 97 percent in the case of pentachlorophenol-treated cells. The point mutation frequencies at 190 base pair and 444 base pair positions are 3-6 folds as high as in those at other mutation positions. It may be that these mutation sites are hot spots induced by pentachlorophenol. These results suggest that the HPRT mutation spectrum can be used as a potential bio marker for assessing a specific environmental risk. (author)

  10. High Energy Astrophysics Science Archive Research Center

    Data.gov (United States)

    National Aeronautics and Space Administration — The High Energy Astrophysics Science Archive Research Center (HEASARC) is the primary archive for NASA missions dealing with extremely energetic phenomena, from...

  11. Building Technologies Research and Integration Center (BTRIC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Building Technologies Research and Integration Center (BTRIC), in the Energy and Transportation Science Division (ETSD) of Oak Ridge National Laboratory (ORNL),...

  12. Accelerator Center for Energy Research (ACER)

    Data.gov (United States)

    Federal Laboratory Consortium — The Accelerator Center for Energy Research (ACER) exploits radiation chemistry techniques to study chemical reactions (and other phenomena) by subjecting samples to...

  13. Information on the Karlsruhe Nuclear Research Center

    International Nuclear Information System (INIS)

    Reuter, H.H.

    1980-01-01

    A short overview is given about the origins of Karlsruhe Nuclear Research Center. The historical development of the different companies operating the Center is shown. Because the original task assigned to the Center was the construction and testing of the first German reactor exclusively built by German companies, a detailed description of this reactor and the changes made afterwards is presented. Next, today's organizational structure of the Center is outlined and the development of the Center's financing since its foundation is shown. A short overview about the structure of employees from the Center's beginning up to now is also included as well as a short description of today's main activities. (orig.)

  14. Nuclear energy research in Germany 2008. Research centers and universities

    International Nuclear Information System (INIS)

    Tromm, Walter

    2009-01-01

    This summary report presents nuclear energy research at research centers and universities in Germany in 2008. Activities are explained on the basis of examples of research projects and a description of the situation of research and teaching in general. Participants are the - Karlsruhe Research Center, - Juelich Research Center (FZJ), - Dresden-Rossendorf Research Center (FZD), - Verein fuer Kernverfahrenstechnik und Analytik Rossendorf e.V. (VKTA), - Technical University of Dresden, - University of Applied Sciences, Zittau/Goerlitz, - Institute for Nuclear Energy and Energy Systems (IKE) at the University of Stuttgart, - Reactor Simulation and Reactor Safety Working Group at the Bochum Ruhr University. (orig.)

  15. Structural Biology and Molecular Applications Research

    Science.gov (United States)

    Part of NCI's Division of Cancer Biology's research portfolio, research and development in this area focuses on enabling technologies, models, and methodologies to support basic and applied cancer research.

  16. Nuclear research center transformation experience

    International Nuclear Information System (INIS)

    Diaz, J. L.; Jimenez, J. M.

    2001-01-01

    As consequence of the changes in the energy polities of each countries in the 80th. many of the Nuclear Research Centres suffered a transformation (more of less deep) in other Research and Development Centres with a wider spectrum that the exclusively nuclear one. This year is the 50 anniversary of the Spanish Centre of Nuclear Research-Junta de Energia Nuclear.The JEN the same as other suffered a deep renovation to become the CIEMAT Centro de Investigaciones Energeticas Medioambientales y Tecnologicas (Research Centre for Energy, Environment and Technology). This paper is focussed on the evolution of JEN to CIEMAT besides analysing the reach of this re-foundation considering the political reasons and technical aspect that justified it and the laws in those it is based on. (Author)

  17. Activity report of Computing Research Center

    Energy Technology Data Exchange (ETDEWEB)

    1997-07-01

    On April 1997, National Laboratory for High Energy Physics (KEK), Institute of Nuclear Study, University of Tokyo (INS), and Meson Science Laboratory, Faculty of Science, University of Tokyo began to work newly as High Energy Accelerator Research Organization after reconstructing and converting their systems, under aiming at further development of a wide field of accelerator science using a high energy accelerator. In this Research Organization, Applied Research Laboratory is composed of four Centers to execute assistance of research actions common to one of the Research Organization and their relating research and development (R and D) by integrating the present four centers and their relating sections in Tanashi. What is expected for the assistance of research actions is not only its general assistance but also its preparation and R and D of a system required for promotion and future plan of the research. Computer technology is essential to development of the research and can communize for various researches in the Research Organization. On response to such expectation, new Computing Research Center is required for promoting its duty by coworking and cooperating with every researchers at a range from R and D on data analysis of various experiments to computation physics acting under driving powerful computer capacity such as supercomputer and so forth. Here were described on report of works and present state of Data Processing Center of KEK at the first chapter and of the computer room of INS at the second chapter and on future problems for the Computing Research Center. (G.K.)

  18. Center for Information Systems Research Research Briefings 2002

    OpenAIRE

    ROSS, JEANNE W.

    2003-01-01

    This paper is comprised of research briefings from the MIT Sloan School of Management's Center for Information Systems Research (CISR). CISR's mission is to perform practical empirical research on how firms generate business value from IT.

  19. Center for Computing Research Summer Research Proceedings 2015.

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, Andrew Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Parks, Michael L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-12-18

    The Center for Computing Research (CCR) at Sandia National Laboratories organizes a summer student program each summer, in coordination with the Computer Science Research Institute (CSRI) and Cyber Engineering Research Institute (CERI).

  20. Natural and Accelerated Bioremediation Research (NABIR) Field Research Center (FRC) Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Watson, D.B.

    2002-02-28

    The Environmental Sciences Division at Oak Ridge National Laboratory has established a Field Research Center (FRC) to support the Natural and Accelerated Bioremediation Research (NABIR) Program on the U.S. Department of Energy (DOE) Oak Ridge Reservation in Oak Ridge, Tennessee for the DOE Headquarters Office of Biological and Environmental Research within the Office of Science.

  1. DOE - BES Nanoscale Science Research Centers (NSRCs)

    Energy Technology Data Exchange (ETDEWEB)

    Beecher, Cathy Jo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-11-14

    These are slides from a powerpoint shown to guests during tours of Center for Integrated Nanotechnologies (CINT) at Los Alamos National Laboratory. It shows the five DOE-BES nanoscale science research centers (NSRCs), which are located at different national laboratories throughout the country. Then it goes into detail specifically about the Center for Integrated Nanotechnologies at LANL, including statistics on its user community and CINT's New Mexico industrial users.

  2. Statistical Tutorial | Center for Cancer Research

    Science.gov (United States)

    Recent advances in cancer biology have resulted in the need for increased statistical analysis of research data.  ST is designed as a follow up to Statistical Analysis of Research Data (SARD) held in April 2018.  The tutorial will apply the general principles of statistical analysis of research data including descriptive statistics, z- and t-tests of means and mean

  3. Haldane's Contributions to Biological Research in India

    Indian Academy of Sciences (India)

    and Industrial Research, New Delhi, he moved to Bhubaneswar to start his own ... Brown, Foreign Secretary, US National Academy of Sciences, in. 1964, upon .... lectures contained new ideas for biological research that could be conducted in ...

  4. THE CENTER FOR MILITARY BIOMECHANICS RESEARCH

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Military Biomechanics Research is a 7,500 ft2 dedicated laboratory outfitted with state-of-the-art equipment for 3-D analysis of movement, measurement...

  5. Johns Hopkins Particulate Matter Research Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Johns Hopkins Particulate Matter Research Center will map health risks of PM across the US based on analyses of national databases on air pollution, mortality,...

  6. National Center on Sleep Disorders Research

    Science.gov (United States)

    ... Resources Register for Updates The National Center on Sleep Disorders Research (NCSDR) Located within the National Heart, Lung, ... 60 percent have a chronic disorder. Each year, sleep disorders, sleep deprivation, and sleepiness add an estimated $15. ...

  7. Center for Drug Evaluation and Research

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Drug Evaluation and Research(CDER) performs an essential public health task by making sure that safe and effective drugs are available to improve the...

  8. CCR Magazines | Center for Cancer Research

    Science.gov (United States)

    The Center for Cancer Research (CCR) has two magazines, MILESTONES and LANDMARKS, that highlight our annual advances and top contributions to the understanding, detection, treatment and prevention of cancer over the years.

  9. Research Centers: Ecstasies & Agonies [in HRD].

    Science.gov (United States)

    1995

    These four papers are from a symposium facilitated by Gene Roth on research centers at the 1995 Academy of Human Resource Development (HRD) conference. "Research: The Thin Blue Line between Rigor and Reality" (Michael Leimbach) discusses the need for HRD research to increase its speed and rigor and help organizations focus on capability…

  10. The biology of Phytophthora infestans at its center of origin

    NARCIS (Netherlands)

    Grünwald, N.J.; Flier, W.G.

    2005-01-01

    The central highlands of Mexico are considered to be a center of genetic diversity for both the potato late blight pathogen and for tuber-bearing Solanum spp. Recent work conducted in Mexico and South America sheds new light on the biology and evolution of Phytophthora infestans and other related

  11. Interdisciplinary research center devoted to molecular environmental science opens

    Science.gov (United States)

    Vaughan, David J.

    In October, a new research center opened at the University of Manchester in the United Kingdom. The center is the product of over a decade of ground-breaking interdisciplinary research in the Earth and related biological and chemical sciences at the university The center also responds to the British governments policy of investing in research infrastructure at key universities.The Williamson Research Centre, the first of its kind in Britain and among the first worldwide, is devoted to the emerging field of molecular environmental science. This field also aims to bring about a revolution in understanding of our environment. Though it may be a less violent revolution than some, perhaps, its potential is high for developments that could affect us all.

  12. Data integration in biological research: an overview.

    Science.gov (United States)

    Lapatas, Vasileios; Stefanidakis, Michalis; Jimenez, Rafael C; Via, Allegra; Schneider, Maria Victoria

    2015-12-01

    Data sharing, integration and annotation are essential to ensure the reproducibility of the analysis and interpretation of the experimental findings. Often these activities are perceived as a role that bioinformaticians and computer scientists have to take with no or little input from the experimental biologist. On the contrary, biological researchers, being the producers and often the end users of such data, have a big role in enabling biological data integration. The quality and usefulness of data integration depend on the existence and adoption of standards, shared formats, and mechanisms that are suitable for biological researchers to submit and annotate the data, so it can be easily searchable, conveniently linked and consequently used for further biological analysis and discovery. Here, we provide background on what is data integration from a computational science point of view, how it has been applied to biological research, which key aspects contributed to its success and future directions.

  13. Karlsruhe nuclear research center. Main activities

    International Nuclear Information System (INIS)

    The article reports on problems of securing the fuel supply for nuclear power generation, on reprocessing and ultimate storage of radioactive material, on the safety of nuclear facilities, on new technologies and basic research, and on the infrastructure of the Karlsruhe nuclear research center, as well as finance and administration. (HK) [de

  14. CCR Interns | Center for Cancer Research

    Science.gov (United States)

    The Cancer Research Interns (CRI) Summer Program was inaugurated in 2004 to provide an open door for students looking for an initial training opportunity. The goal is to enhance diversity within the CCR (Center for Cancer Research) training program and we have placed 338 students from 2004 to 2017, in labs and branches across the division.  The CCR and the Center for Cancer Training’s Office of Training and Education provide stipend support, some Service & Supply funds, and travel support for those students who meet the financial eligibility criteria (

  15. Synthesis centers as critical research infrastructure

    Science.gov (United States)

    Baron, Jill S.; Specht, Alison; Garnier, Eric; Bishop, Pamela; Campbell, C. Andrew; Davis, Frank W.; Fady, Bruno; Field, Dawn; Gross, Louis J.; Guru, Siddeswara M.; Halpern, Benjamin S; Hampton, Stephanie E.; Leavitt, Peter R.; Meagher, Thomas R.; Ometto, Jean; Parker, John N.; Price, Richard; Rawson, Casey H.; Rodrigo, Allen; Sheble, Laura A.; Winter, Marten

    2017-01-01

    investment to maximize benefits to science and society is justified. In particular, we argue that synthesis centers represent community infrastructure more akin to research vessels than to term-funded centers of science and technology (e.g., NSF Science and Technology Centers). Through our experience running synthesis centers and, in some cases, developing postfederal funding models, we offer our perspective on the purpose and value of synthesis centers. We present case studies of different outcomes of transition plans and argue for a fundamental shift in the conception of synthesis science and the strategic funding of these centers by government funding agencies.

  16. Managing a Modern University Research Center.

    Science.gov (United States)

    Veres, John G., III

    1988-01-01

    The university research center of the future will function best to serve the rapidly changing public and private demand for services with a highly trained core staff, adequately funded and equipped, whose morale and quality of work performance is a prime consideration. (MSE)

  17. Role Strain in University Research Centers

    Science.gov (United States)

    Boardman, Craig; Bozeman, Barry

    2007-01-01

    One way in which university faculty members' professional lives have become more complex with the advent of contemporary university research centers is that many faculty have taken on additional roles. The authors' concern in this article is to determine the extent to which role strain is experienced by university faculty members who are…

  18. The Strategic Electrochemical Research Center in Denmark

    DEFF Research Database (Denmark)

    Mogensen, Mogens Bjerg; Hansen, Karin Vels

    2011-01-01

    A 6-year strategic electrochemistry research center (SERC) in fundamental and applied aspects of electrochemical cells with a main emphasis on solid oxide cells was started in Denmark on January 1st, 2007 in cooperation with other Danish and Swedish Universities. Furthermore, 8 Danish companies...... are presented. ©2011 COPYRIGHT ECS - The Electrochemical Society...

  19. Staff Clinician | Center for Cancer Research

    Science.gov (United States)

    The Neuro-Oncology Branch (NOB), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH) is seeking staff clinicians to provide high-quality patient care for individuals with primary central nervous system (CNS) malignancies.  The NOB is comprised of a multidisciplinary team of physicians, healthcare providers, and scientists who

  20. Lewis Research Center R and D Facilities

    Science.gov (United States)

    1991-01-01

    The NASA Lewis Research Center (LeRC) defines and develops advanced technology for high priority national needs. The work of the Center is directed toward new propulsion, power, and communications technologies for application to aeronautics and space, so that U.S. leadership in these areas is ensured. The end product is knowledge, usually in a report, that is made fully available to potential users--the aircraft engine industry, the energy industry, the automotive industry, the space industry, and other NASA centers. In addition to offices and laboratories for almost every kind of physical research in such fields as fluid mechanics, physics, materials, fuels, combustion, thermodynamics, lubrication, heat transfer, and electronics, LeRC has a variety of engineering test cells for experiments with components such as compressors, pumps, conductors, turbines, nozzles, and controls. A number of large facilities can simulate the operating environment for a complete system: altitude chambers for aircraft engines; large supersonic wind tunnels for advanced airframes and propulsion systems; space simulation chambers for electric rockets or spacecraft; and a 420-foot-deep zero-gravity facility for microgravity experiments. Some problems are amenable to detection and solution only in the complete system and at essentially full scale. By combining basic research in pertinent disciplines and generic technologies with applied research on components and complete systems, LeRC has become one of the most productive centers in its field in the world. This brochure describes a number of the facilities that provide LeRC with its exceptional capabilities.

  1. AHPCRC - Army High Performance Computing Research Center

    Science.gov (United States)

    2010-01-01

    computing. Of particular interest is the ability of a distrib- uted jamming network (DJN) to jam signals in all or part of a sensor or communications net...and reasoning, assistive technologies. FRIEDRICH (FRITZ) PRINZ Finmeccanica Professor of Engineering, Robert Bosch Chair, Department of Engineering...High Performance Computing Research Center www.ahpcrc.org BARBARA BRYAN AHPCRC Research and Outreach Manager, HPTi (650) 604-3732 bbryan@hpti.com Ms

  2. Nuclear Research Center IRT reactor dynamics calculation

    International Nuclear Information System (INIS)

    Aleman Fernandez, J.R.

    1990-01-01

    The main features of the code DIRT, for dynamical calculations are described in the paper. With the results obtained by the program, an analysis of the dynamic behaviour of the Research Reactor IRT of the Nuclear Research Center (CIN) is performed. Different transitories were considered such as variation of the system reactivity, coolant inlet temperature variation and also variations of the coolant velocity through the reactor core. 3 refs

  3. Interaction Modeling at PROS Research Center

    OpenAIRE

    Panach , José ,; Aquino , Nathalie; PASTOR , Oscar

    2011-01-01

    Part 1: Long and Short Papers; International audience; This paper describes how the PROS Research Center deals with interaction in the context of a model-driven approach for the development of information systems. Interaction is specified in a conceptual model together with the structure and behavior of the system. Major achievements and current research challenges of PROS in the field of interaction modeling are presented.

  4. South African antarctic biological research programme

    CSIR Research Space (South Africa)

    SASCAR

    1981-07-01

    Full Text Available This document provides a description of the past, current and planned South African biological research activities in the sub-Antarctic and Antarctic regions. Future activities will fall under one of the five components of the research programme...

  5. The Wetland and Aquatic Research Center strategic science plan

    Science.gov (United States)

    ,

    2017-02-02

    IntroductionThe U.S. Geological Survey (USGS) Wetland and Aquatic Research Center (WARC) has two primary locations (Gainesville, Florida, and Lafayette, Louisiana) and field stations throughout the southeastern United States and Caribbean. WARC’s roots are in U.S. Fish and Wildlife Service (USFWS) and National Park Service research units that were brought into the USGS as the Biological Research Division in 1996. Founded in 2015, WARC was created from the merger of two long-standing USGS biology science Centers—the Southeast Ecological Science Center and the National Wetlands Research Center—to bring together expertise in biology, ecology, landscape science, geospatial applications, and decision support in order to address issues nationally and internationally. WARC scientists apply their expertise to a variety of wetland and aquatic research and monitoring issues that require coordinated, integrated efforts to better understand natural environments. By increasing basic understanding of the biology of important species and broader ecological and physiological processes, this research provides information to policymakers and aids managers in their stewardship of natural resources and in regulatory functions.This strategic science plan (SSP) was developed to guide WARC research during the next 5–10 years in support of Department of the Interior (DOI) partnering bureaus such as the USFWS, the National Park Service, and the Bureau of Ocean Energy Management, as well as other Federal, State, and local natural resource management agencies. The SSP demonstrates the alignment of the WARC goals with the USGS mission areas, associated programs, and other DOI initiatives. The SSP is necessary for workforce planning and, as such, will be used as a guide for future needs for personnel. The SSP also will be instrumental in developing internal funding priorities and in promoting WARC’s capabilities to both external cooperators and other groups within the USGS.

  6. Radioactive 63Ni in biological research

    International Nuclear Information System (INIS)

    Kasprzak, K.S.; Sunderman, F.W. Jr.

    1979-01-01

    Applications of 63 Ni in biological research are reviewed, with emphasis upon recent investigations of nickel metabolism and toxicology in experimental animals. The radiochemistry of 63 Ni is summarized, including consideration of the preparation of certain 63 Ni compounds (e.g. 63 Ni(CO) 4 and 63 Ni 3 S 2 ) that are of current interest in toxicology, teratology and cancer research. Practical guidance is given regarding the detection and determination of 63 Ni in biological materials by autoradiography and liquid scintillation spectrometry. (author)

  7. Proceedings of RIKEN BNL Research Center Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Samios, Nicholas P. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2013-01-24

    The twelfth evaluation of the RIKEN BNL Research Center (RBRC) took place on November 6 – 8, 2012 at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC), present at the meeting, were: Prof. Wit Busza, Prof. Miklos Gyulassy, Prof. Kenichi Imai, Prof. Richard Milner (Chair), Prof. Alfred Mueller, Prof. Charles Young Prescott, and Prof. Akira Ukawa. We are pleased that Dr. Hideto En’yo, the Director of the Nishina Institute of RIKEN, Japan, participated in this meeting both in informing the committee of the activities of the RIKEN Nishina Center for Accelerator- Based Science and the role of RBRC and as an observer of this review. In order to illustrate the breadth and scope of the RBRC program, each member of the Center made a presentation on his/her research efforts. This encompassed three major areas of investigation: theoretical, experimental and computational physics. In addition, the committee met privately with the fellows and postdocs to ascertain their opinions and concerns. Although the main purpose of this review is a report to RIKEN management on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment.

  8. Data Curation Education in Research Centers (DCERC)

    Science.gov (United States)

    Marlino, M. R.; Mayernik, M. S.; Kelly, K.; Allard, S.; Tenopir, C.; Palmer, C.; Varvel, V. E., Jr.

    2012-12-01

    Digital data both enable and constrain scientific research. Scientists are enabled by digital data to develop new research methods, utilize new data sources, and investigate new topics, but they also face new data collection, management, and preservation burdens. The current data workforce consists primarily of scientists who receive little formal training in data management and data managers who are typically educated through on-the-job training. The Data Curation Education in Research Centers (DCERC) program is investigating a new model for educating data professionals to contribute to scientific research. DCERC is a collaboration between the University of Illinois at Urbana-Champaign Graduate School of Library and Information Science, the University of Tennessee School of Information Sciences, and the National Center for Atmospheric Research. The program is organized around a foundations course in data curation and provides field experiences in research and data centers for both master's and doctoral students. This presentation will outline the aims and the structure of the DCERC program and discuss results and lessons learned from the first set of summer internships in 2012. Four masters students participated and worked with both data mentors and science mentors, gaining first hand experiences in the issues, methods, and challenges of scientific data curation. They engaged in a diverse set of topics, including climate model metadata, observational data management workflows, and data cleaning, documentation, and ingest processes within a data archive. The students learned current data management practices and challenges while developing expertise and conducting research. They also made important contributions to NCAR data and science teams by evaluating data management workflows and processes, preparing data sets to be archived, and developing recommendations for particular data management activities. The master's student interns will return in summer of 2013

  9. 70 Years of Aeropropulsion Research at NASA Glenn Research Center

    Science.gov (United States)

    Reddy, Dhanireddy R.

    2013-01-01

    This paper presents a brief overview of air-breathing propulsion research conducted at the NASA Glenn Research Center (GRC) over the past 70 years. It includes a historical perspective of the center and its various stages of propulsion research in response to the countrys different periods of crises and growth opportunities. GRCs research and technology development covered a broad spectrum, from a short-term focus on improving the energy efficiency of aircraft engines to advancing the frontier technologies of high-speed aviation in the supersonic and hypersonic speed regimes. This paper highlights major research programs, showing their impact on industry and aircraft propulsion, and briefly discusses current research programs and future aeropropulsion technology trends in related areas

  10. 75 FR 6651 - Biological and Environmental Research Advisory Committee

    Science.gov (United States)

    2010-02-10

    ... DEPARTMENT OF ENERGY Biological and Environmental Research Advisory Committee AGENCY: Department... meeting of the Biological and Environmental Research Advisory Committee (BERAC). Federal Advisory.... Department of Energy, Office of Science, Office of Biological and Environmental Research, SC-23/Germantown...

  11. 77 FR 4028 - Biological and Environmental Research Advisory Committee

    Science.gov (United States)

    2012-01-26

    ... DEPARTMENT OF ENERGY Biological and Environmental Research Advisory Committee AGENCY: Department... meeting of the Biological and Environmental Research Advisory Committee (BERAC). The Federal Advisory.... Department of Energy, Office of Science, Office of Biological and Environmental Research, SC-23/Germantown...

  12. Molecular Science Research Center 1992 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Knotek, M.L.

    1994-01-01

    The Molecular Science Research Center is a designated national user facility, available to scientists from universities, industry, and other national laboratories. After an opening section, which includes conferences hosted, appointments, and projects, this document presents progress in the following fields: chemical structure and dynamics; environmental dynamics and simulation; macromolecular structure and dynamics; materials and interfaces; theory, modeling, and simulation; and computing and information sciences. Appendices are included: MSRC staff and associates, 1992 publications and presentations, activities, and acronyms and abbreviations.

  13. CSBB: synthetic biology research at Newcastle University.

    Science.gov (United States)

    Goñi-Moreno, Angel; Wipat, Anil; Krasnogor, Natalio

    2017-06-15

    The Centre for Synthetic Biology and the Bioeconomy (CSBB) brings together a far-reaching multidisciplinary community across all Newcastle University's faculties - Medical Sciences, Science, Agriculture and Engineering, and Humanities, Arts and Social Sciences. The CSBB focuses on many different areas of Synthetic Biology, including bioprocessing, computational design and in vivo computation, as well as improving understanding of basic molecular machinery. Such breadth is supported by major national and international research funding, a range of industrial partners in the North East of England and beyond, as well as a large number of doctoral and post-doctoral researchers. The CSBB trains the next generation of scientists through a 1-year MSc in Synthetic Biology. © 2017 The Author(s).

  14. RCOP: Research Center for Optical Physics

    Science.gov (United States)

    Tabibi, Bagher M. (Principal Investigator)

    1996-01-01

    During the five years since its inception, Research Center for Optical Physics (RCOP) has excelled in the goals stated in the original proposal: 1) training of the scientists and engineers needed for the twenty-first century with special emphasis on underrepresented citizens and 2) research and technological development in areas of relevance to NASA. In the category of research training, there have been 16 Bachelors degrees and 9 Masters degrees awarded to African American students working in RCOP during the last five years. RCOP has also provided research experience to undergraduate and high school students through a number of outreach programs held during the summer and the academic year. RCOP has also been instrumental in the development of the Ph.D. program in physics which is in its fourth year at Hampton. There are currently over 40 graduate students in the program and 9 African American graduate students, working in RCOP, that have satisfied all of the requirements for Ph.D. candidancy and are working on their dissertation research. At least three of these students will be awarded their doctoral degrees during 1997. RCOP has also excelled in research and technological development. During the first five years of existence, RCOP researchers have generated well over $3 M in research funding that directly supports the Center. Close ties with NASA Langley and NASA Lewis have been established, and collaborations with NASA scientists, URC's and other universities as well as with industry have been developed. This success is evidenced by the rate of publishing research results in refereed journals, which now exceeds that of the goals in the original proposal (approx. 2 publications per faculty per year). Also, two patents have been awarded to RCOP scientists.

  15. Scientist, Single Cell Analysis Facility | Center for Cancer Research

    Science.gov (United States)

    The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR).  The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and nextGen sequencing. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR).  CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES AND RESPONSIBILITIES We are seeking a highly motivated Scientist II to join the newly established Single Cell Analysis Facility (SCAF) of the Center for Cancer Research (CCR) at NCI. The SCAF will house state of the art single cell sequencing technologies including 10xGenomics Chromium, BD Genomics Rhapsody, DEPPArray, and other emerging single cell technologies. The Scientist: Will interact with close to 200 laboratories within the CCR to design and carry out single cell experiments for cancer research Will work on single cell isolation/preparation from various tissues and cells and related NexGen sequencing library preparation Is expected to author publications in peer reviewed scientific journals

  16. Biologically Inspired Micro-Flight Research

    Science.gov (United States)

    Raney, David L.; Waszak, Martin R.

    2003-01-01

    Natural fliers demonstrate a diverse array of flight capabilities, many of which are poorly understood. NASA has established a research project to explore and exploit flight technologies inspired by biological systems. One part of this project focuses on dynamic modeling and control of micro aerial vehicles that incorporate flexible wing structures inspired by natural fliers such as insects, hummingbirds and bats. With a vast number of potential civil and military applications, micro aerial vehicles represent an emerging sector of the aerospace market. This paper describes an ongoing research activity in which mechanization and control concepts for biologically inspired micro aerial vehicles are being explored. Research activities focusing on a flexible fixed- wing micro aerial vehicle design and a flapping-based micro aerial vehicle concept are presented.

  17. Postdoctoral Fellow | Center for Cancer Research

    Science.gov (United States)

    Highly motivated postdoctoral fellows sought to work on tumor immunology with a strong background in biology preferentially cellular immunology. The tumor immunology group in the laboratory is exploring mechanisms of improving vaccines and immunotherapy for cancer, especially by discovering new principles to enhance and steer T cell immune responses. The group is focusing on negative immunoregulatory mechanisms used for immune evasion by cancer cells. The postdoctoral fellow will work on a project to understand the negative regulatory mechanisms of tumor immunity especially the mechanisms initiated by NKT cells. Group members also have an opportunity to gain knowledge of HIV/mucosal immunology by interacting with the HIV research group in the lab.

  18. 78 FR 6087 - Biological and Environmental Research Advisory Committee

    Science.gov (United States)

    2013-01-29

    ... DEPARTMENT OF ENERGY Biological and Environmental Research Advisory Committee AGENCY: Office of... the Biological and Environmental Research Advisory Committee (BERAC). The Federal Advisory Committee... Federal Officer, BERAC, U.S. Department of Energy, Office of Science, Office of Biological and...

  19. Radiation protection at the Cadarache research center

    International Nuclear Information System (INIS)

    Anon.

    2015-01-01

    This article recalls the French law about radiation protection and its evolution due to the implementation of the 2013/59-EURATOM directive that separates the missions of counsel from the more operative missions of the person appointed as 'competent in radiation protection'. The organisation of the radiation protection of the Cadarache research center is presented. The issue of sub-contracting and the respect of an adequate standard of radioprotection is detailed since 2 facilities operated by AREVA are being dismantled on the site. (A.C.)

  20. Atomic, Nuclear and Molecular Research Center CICANUM

    International Nuclear Information System (INIS)

    Loria Meneses, Luis Guillermo

    2011-01-01

    CICANUM has a Gamma Spectroscopy Laboratory, has been the laboratory official, appointed by the Ministerio de Agricultura in Costa Rica to analyze export products (for human consumption and animal), also, to determine radioactive contamination. The Laboratory has four systems using germanium detectors and canberra technology, including software Genie 2000 to establish the activity of cesium, iodine and natural gamma emitters in solid or liquid samples for food products, sediments and rocks. This Laboratory belongs to the Universidad de Costa Rica which has different institutes and research centers

  1. NASA Langley Research Center tethered balloon systems

    Science.gov (United States)

    Owens, Thomas L.; Storey, Richard W.; Youngbluth, Otto

    1987-01-01

    The NASA Langley Research Center tethered balloon system operations are covered in this report for the period of 1979 through 1983. Meteorological data, ozone concentrations, and other data were obtained from in situ measurements. The large tethered balloon had a lifting capability of 30 kilograms to 2500 meters. The report includes descriptions of the various components of the balloon systems such as the balloons, the sensors, the electronics, and the hardware. Several photographs of the system are included as well as a list of projects including the types of data gathered.

  2. Molecular Science Research Center annual report

    Energy Technology Data Exchange (ETDEWEB)

    Knotek, M.L.

    1991-01-01

    The Chemical Structure and Dynamics group is studying chemical kinetics and reactions dynamics of terrestrial and atmospheric processes as well as the chemistry of complex waste forms and waste storage media. Staff are using new laser systems and surface-mapping techniques in combination with molecular clusters that mimic adsorbate/surface interactions. The Macromolecular Structure and Dynamics group is determining biomolecular structure/function relationships for processes the control the biological transformation of contaminants and the health effects of toxic substances. The Materials and Interfaces program is generating information needed to design and synthesize advanced materials for the analysis and separation of mixed chemical waste, the long-term storage of concentrated hazardous materials, and the development of chemical sensors for environmental monitoring of various organic and inorganic species. The Theory, Modeling, and Simulation group is developing detailed molecular-level descriptions of the chemical, physical, and biological processes in natural and contaminated systems. Researchers are using the full spectrum of computational techniques. The Computer and Information Sciences group is developing new approaches to handle vast amounts of data and to perform calculations for complex natural systems. The EMSL will contain a high-performance computing facility, ancillary computing laboratories, and high-speed data acquisition systems for all major research instruments.

  3. MedAustron - Ion-Beam Therapy and Research Center

    International Nuclear Information System (INIS)

    Schreiner, Thomas; Seemann, Rolf

    2015-01-01

    MedAustron is a synchrotron-based light-ion beam therapy center for cancer treatment as well as for clinical and non-clinical research, currently in the commissioning phase in Wiener Neustadt, Austria. Recently, the first proton beam was transported successfully to one of the four irradiation rooms. Whilst the choice of basic machine parameters was driven by medical requirements, i.e. 60 MeV protons and 120 MeV/A to 400 MeV/A carbon ions, the accelerator complex design was also optimized to offer flexibility for research operation. The potential of the synchrotron is being exploited to increase the maximum proton energy far beyond the medical needs to up to 800 MeV, for experimental physics applications, mainly in the areas of proton scattering and detector research. The accelerator layout allows for the installation of up to four ion source-spectrometer units, to provide various ion types besides the clinical used protons and carbon ions. Besides experimental physics, the two main non-clinical research disciplines are medical radiation physics and radiation biology. To decouple research and medical operation, a dedicated irradiation room for non-clinical research was included providing the installation of different experiments. In addition, several labs have been equipped with appropriate devices for preparing and analyzing radio-biological samples. This presentation gives a status overview over the whole project and highlights the non-clinical research opportunities at MedAustron. (Author)

  4. Nuclear Criticality Experimental Research Center (NCERC) Overview

    Energy Technology Data Exchange (ETDEWEB)

    Goda, Joetta Marie [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Grove, Travis Justin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hayes, David Kirk [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Myers, William L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sanchez, Rene Gerardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-03

    The mission of the National Criticality Experiments Research Center (NCERC) at the Device Assembly Facility (DAF) is to conduct experiments and training with critical assemblies and fissionable material at or near criticality in order to explore reactivity phenomena, and to operate the assemblies in the regions from subcritical through delayed critical. One critical assembly, Godiva-IV, is designed to operate above prompt critical. The Nuclear Criticality Experimental Research Center (NCERC) is our nation’s only general-purpose critical experiments facility and is only one of a few that remain operational throughout the world. This presentation discusses the history of NCERC, the general activities that makeup work at NCERC, and the various government programs and missions that NCERC supports. Recent activities at NCERC will be reviewed, with a focus on demonstrating how NCERC meets national security mission goals using engineering fundamentals. In particular, there will be a focus on engineering theory and design and applications of engineering fundamentals at NCERC. NCERC activities that relate to engineering education will also be examined.

  5. Sulfur-centered reactive intermediates derived from the oxidation of sulfur compounds of biological interest

    Energy Technology Data Exchange (ETDEWEB)

    Abedinzadeh, Z. [Lab. de Chimie Physique, UMR, Univ. Rene Descartes, Paris (France)

    2001-02-01

    Sulphur compounds play a central role in the structure and activity of many vital systems. In the living cell, sulfur constitutes an essential part of the defense against oxidative damage and is transformed into a variety of sulfur free radical species. Many studies of the chemistry of sulfur-centered radicals using pulse radiolysis and photolysis techniques to detect and measure the kinetics of these radicals have been published and reviewed. This paper discusses the present state of research on the formation and reactivity of certain sulfur-centered radicals [RS{sup .}, RSS{sup .}, RS{sup .+}, (RSSR){sup .+}] and their implications for biological systems. (author)

  6. Sulfur-centered reactive intermediates derived from the oxidation of sulfur compounds of biological interest

    International Nuclear Information System (INIS)

    Abedinzadeh, Z.

    2001-01-01

    Sulphur compounds play a central role in the structure and activity of many vital systems. In the living cell, sulfur constitutes an essential part of the defense against oxidative damage and is transformed into a variety of sulfur free radical species. Many studies of the chemistry of sulfur-centered radicals using pulse radiolysis and photolysis techniques to detect and measure the kinetics of these radicals have been published and reviewed. This paper discusses the present state of research on the formation and reactivity of certain sulfur-centered radicals [RS . , RSS . , RS .+ , (RSSR) .+ ] and their implications for biological systems. (author)

  7. Onchocerciasis control: biological research is still needed

    Directory of Open Access Journals (Sweden)

    Boussinesq M.

    2008-09-01

    Full Text Available Achievements obtained by the onchocerciasis control programmes should not lead to a relaxation in the biological research on Onchocerca volvulus. Issues such as the Loa loa-related postivermectin serious adverse events, the uncertainties as to whether onchocerciasis can be eliminated by ivermectin treatments, and the possible emergence of ivermectin-resistant O. volvulus populations should be addressed proactively. Doxycycline, moxidectin and emodepside appear to be promising as alternative drugs against onchocerciasis but support to researches in immunology and genomics should also be increased to develop new control tools, including both vaccines and macrofilaricidal drugs.

  8. Research Center Renaming Will Honor Senator Domenici

    Science.gov (United States)

    2008-05-01

    New Mexico Tech and the National Radio Astronomy Observatory (NRAO) will rename the observatory's research center on the New Mexico Tech campus to honor retiring U.S. Senator Pete V. Domenici in a ceremony on May 30. The building that serves as the scientific, technical, and administrative center for the Very Large Array (VLA) and Very Long Baseline Array (VLBA) radio telescopes will be named the "Pete V. Domenici Science Operations Center." The building previously was known simply as the "Array Operations Center." Sen. Pete V. Domenici Sen. Pete V. Domenici "The new name recognizes the strong and effective support for science that has been a hallmark of Senator Domenici's long career in public service," said Dr. Fred Lo, NRAO Director. New Mexico Tech President Daniel H. Lopez said Sen. Domenici has always been a supporter of science and research in Socorro and throughout the state. "He's been a statesman for New Mexico, the nation -- and without exaggeration -- for the world," Lopez said. "Anyone with that track record deserves this recognition." Van Romero, Tech vice president of research and economic development, has served as the university's main lobbyist in Washington, D.C., for more than a decade. He said Sen. Domenici has always been receptive to new ideas and willing to take risks. "Over the years, Sen. Domenici has always had time to listen to our needs and goals," Romero said. "He has served as a champion of New Mexico Tech's causes and we owe him a debt of gratitude for all his efforts over the decades." Originally dedicated in 1988, the center houses offices and laboratories that support VLA and VLBA operations. The center also supports work on the VLA modernization project and on the international Atacama Large Millimeter/submillimeter Array (ALMA) project. Work on ALMA at the Socorro center and at the ALMA Test Facility at the VLA site west of Socorro has focused on developing and testing equipment to be deployed at the ALMA site in Chile's Atacama

  9. Biological effectiveness of neutrons: Research needs

    Energy Technology Data Exchange (ETDEWEB)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

  10. Biological effectiveness of neutrons: Research needs

    International Nuclear Information System (INIS)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy

  11. Solar Energy Research Center Instrumentation Facility

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Thomas, J.; Papanikolas, John, P.

    2011-11-11

    SOLAR ENERGY RESEARCH CENTER INSTRUMENTATION FACILITY The mission of the Solar Energy Research Center (UNC SERC) at the University of North Carolina at Chapel Hill (UNC-CH) is to establish a world leading effort in solar fuels research and to develop the materials and methods needed to fabricate the next generation of solar energy devices. We are addressing the fundamental issues that will drive new strategies for solar energy conversion and the engineering challenges that must be met in order to convert discoveries made in the laboratory into commercially available devices. The development of a photoelectrosynthesis cell (PEC) for solar fuels production faces daunting requirements: (1) Absorb a large fraction of sunlight; (2) Carry out artificial photosynthesis which involves multiple complex reaction steps; (3) Avoid competitive and deleterious side and reverse reactions; (4) Perform 13 million catalytic cycles per year with minimal degradation; (5) Use non-toxic materials; (6) Cost-effectiveness. PEC efficiency is directly determined by the kinetics of each reaction step. The UNC SERC is addressing this challenge by taking a broad interdisciplinary approach in a highly collaborative setting, drawing on expertise across a broad range of disciplines in chemistry, physics and materials science. By taking a systematic approach toward a fundamental understanding of the mechanism of each step, we will be able to gain unique insight and optimize PEC design. Access to cutting-edge spectroscopic tools is critical to this research effort. We have built professionally-staffed facilities equipped with the state-of the-art instrumentation funded by this award. The combination of staff, facilities, and instrumentation specifically tailored for solar fuels research establishes the UNC Solar Energy Research Center Instrumentation Facility as a unique, world-class capability. This congressionally directed project funded the development of two user facilities: TASK 1: SOLAR

  12. Idaho national laboratory - a nuclear research center

    International Nuclear Information System (INIS)

    Zaidi Mohammed, K.

    2006-01-01

    Full text: The Idaho National Laboratory (INL) is committed to providing international nuclear leadership for the 21st Century, developing and demonstrating compelling national security technologies, and delivering excellence in science and technology as one of the United States Department of Energy's (DOE) multi program national laboratories. INL runs three major programs - Nuclear, Security and Science. Nuclear programs covers the Advanced test reactor, Six Generation IV technology concepts selected for Rand D, targeting tumors - Boron Neutron Capture therapy. Homeland Security establishes the Control System Security and Test Center, Critical Infrastructure Test Range evaluates technologies on a scalable basis, INL conducts high performance computing and visualization research and science. To provide leadership in the education and training, INL has established an Institute of Nuclear Science and Engineering (INSE) under the Center for Advanced Energy Studies (CAES) and the Idaho State University (ISU). INSE will offer a four year degree based on a newly developed curriculum - two year of basic science course work and two years of participation in project planning and development. The students enrolled in this program can continue to get a masters or a doctoral degree. This summer INSE is the host for the training of the first international group selected by the World Nuclear University (WNU) - 75 fellowship holders and their 30 instructors from 40 countries. INL has been assigned to provide future global leadership in the field of nuclear science and technology. Here, at INL, we keep safety first above all things and our logo is 'Nuclear leadership synonymous with safety leadership'. (author)

  13. Patient Care Coordinator | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  14. Gordon Research Conference on Mammary Gland Biology

    International Nuclear Information System (INIS)

    1989-01-01

    The 1989 conference was the tenth in the series of biennial Gordon Research Conferences on Mammary Gland Biology. Traditionally this conference brings together scientists from diverse backgrounds and experience but with a common interest in the biology of the mammary gland. Investigators from agricultural and medical schools, biochemists, cell and molecular biologists, endocrinologists, immunologists, and representatives from the emerging biotechnology industries met to discuss current concepts and results on the function and regulation of the normal and neoplastic mammary gland in a variety of species. Of the participants, approximately three-fourths were engaged in studying the normal mammary gland function, whereas the other quarter were engaged in studying the neoplastic gland. The interactions between scientists, clinicians, veterinarians examining both normal and neoplastic cell function serves to foster the multi-disciplinary goals of the conference and has stimulated many cooperative projects among participants in previous years

  15. Suborbital Science Program: Dryden Flight Research Center

    Science.gov (United States)

    DelFrate, John

    2008-01-01

    This viewgraph presentation reviews the suborbital science program at NASA Dryden Flight Research Center. The Program Objectives are given in various areas: (1) Satellite Calibration and Validation (Cal/val)--Provide methods to perform the cal/val requirements for Earth Observing System satellites; (2) New Sensor Development -- Provide methods to reduce risk for new sensor concepts and algorithm development prior to committing sensors to operations; (3) Process Studies -- Facilitate the acquisition of high spatial/temporal resolution focused measurements that are required to understand small atmospheric and surface structures which generate powerful Earth system effects; and (4) Airborne Networking -- Develop disruption-tolerant networking to enable integrated multiple scale measurements of critical environmental features. Dryden supports the NASA Airborne Science Program and the nation in several elements: ER-2, G-3, DC-8, Ikhana (Predator B) & Global Hawk and Reveal. These are reviewed in detail in the presentation.

  16. Superconducting microwave electronics at Lewis Research Center

    Science.gov (United States)

    Warner, Joseph D.; Bhasin, Kul B.; Leonard, Regis F.

    Over the last three years, NASA Lewis Research Center has investigated the application of newly discovered high temperature superconductors to microwave electronics. Using thin films of YBa2Cu3O7-delta and Tl2Ca2Ba2Cu3Ox deposited on a variety of substrates, including strontium titanate, lanthanum gallate, lanthanum aluminate and magnesium oxide, a number of microwave circuits have been fabricated and evaluated. These include a cavity resonator at 60 GHz, microstrip resonators at 35 GHz, a superconducting antenna array at 35 GHz, a dielectric resonator at 9 GHz, and a microstrip filter at 5 GHz. Performance of some of these circuits as well as suggestions for other applications are reported.

  17. Superconducting Microwave Electronics at Lewis Research Center

    Science.gov (United States)

    Warner, Joseph D.; Bhasin, Kul B.; Leonard, Regis F.

    1991-01-01

    Over the last three years, NASA Lewis Research Center has investigated the application of newly discovered high temperature superconductors to microwave electronics. Using thin films of YBa2Cu3O7-delta and Tl2Ca2Ba2Cu3Ox deposited on a variety of substrates, including strontium titanate, lanthanum gallate, lanthanum aluminate and magnesium oxide, a number of microwave circuits have been fabricated and evaluated. These include a cavity resonator at 60 GHz, microstrip resonators at 35 GHz, a superconducting antenna array at 35 GHz, a dielectric resonator at 9 GHz, and a microstrip filter at 5 GHz. Performance of some of these circuits as well as suggestions for other applications are reported.

  18. Molecular Science Research Center, 1991 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Knotek, M.L.

    1992-03-01

    During 1991, the Molecular Science Research Center (MSRC) experienced solid growth and accomplishment and the Environmental, and Molecular Sciences Laboratory (EMSL) construction project moved forward. We began with strong programs in chemical structure and dynamics and theory, modeling, and simulation, and both these programs continued to thrive. We also made significant advances in the development of programs in materials and interfaces and macromolecular structure and dynamics, largely as a result of the key staff recruited to lead these efforts. If there was one pervasive activity for the past year, however, it was to strengthen the role of the EMSL in the overall environmental restoration and waste management (ER/WM) mission at Hanford. These extended activities involved not only MSRC and EMSL staff but all PNL scientific and technical staff engaged in ER/WM programs.

  19. Mississippi State University Sustainable Energy Research Center

    Energy Technology Data Exchange (ETDEWEB)

    Steele, W. Glenn [Mississippi State Univ., Mississippi State, MS (United States)

    2014-09-26

    The Sustainable Energy Research Center (SERC) project at Mississippi State University included all phases of biofuel production from feedstock development, to conversion to liquid transportation fuels, to engine testing of the fuels. The feedstocks work focused on non-food based crops and yielded an increased understanding of many significant Southeastern feedstocks. an emphasis was placed on energy grasses that could supplement the primary feedstock, wood. Two energy grasses, giant miscanthus and switchgrass, were developed that had increased yields per acre. Each of these grasses was patented and licensed to companies for commercialization. The fuels work focused on three different technologies that each led to a gasoline, diesel, or jet fuel product. The three technologies were microbial oil, pyrolysis oil, and syngas-to liquid-hydrocarbons

  20. Developmental Scientist | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  1. Genomics:GTL Bioenergy Research Centers White Paper

    Energy Technology Data Exchange (ETDEWEB)

    Mansfield, Betty Kay [ORNL; Alton, Anita Jean [ORNL; Andrews, Shirley H [ORNL; Bownas, Jennifer Lynn [ORNL; Casey, Denise [ORNL; Martin, Sheryl A [ORNL; Mills, Marissa [ORNL; Nylander, Kim [ORNL; Wyrick, Judy M [ORNL; Drell, Dr. Daniel [Office of Science, Department of Energy; Weatherwax, Sharlene [U.S. Department of Energy; Carruthers, Julie [U.S. Department of Energy

    2006-08-01

    In his Advanced Energy Initiative announced in January 2006, President George W. Bush committed the nation to new efforts to develop alternative sources of energy to replace imported oil and fossil fuels. Developing cost-effective and energy-efficient methods of producing renewable alternative fuels such as cellulosic ethanol from biomass and solar-derived biofuels will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy production methods will not suffice. The Genomics:GTL Bioenergy Research Centers will be dedicated to fundamental research on microbe and plant systems with the goal of developing knowledge that will advance biotechnology-based strategies for biofuels production. The aim is to spur substantial progress toward cost-effective production of biologically based renewable energy sources. This document describes the rationale for the establishment of the centers and their objectives in light of the U.S. Department of Energy's mission and goals. Developing energy-efficient and cost-effective methods of producing alternative fuels such as cellulosic ethanol from biomass will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy-production methods will not suffice. The focus on microbes (for cellular mechanisms) and plants (for source biomass) fundamentally exploits capabilities well known to exist in the microbial world. Thus 'proof of concept' is not required, but considerable basic research into these capabilities remains an urgent priority. Several developments have converged in recent years to suggest that systems biology research into microbes and plants promises solutions that will overcome critical roadblocks on the path to cost-effective, large-scale production of cellulosic ethanol and other renewable energy from biomass. The ability to rapidly sequence the DNA of any organism is a critical part of these new

  2. Together with Research Centers and Universities

    Directory of Open Access Journals (Sweden)

    Nuno Domingos Garrido

    2016-10-01

    Full Text Available The Journal Motricidade has always been walking in parallel with the scientific communities. We found that the affiliation of most authors has, nearly always, a University (Uni or a Research Center (RC. In fact it is almost impossible to conduct research outside these two universes. In this sense, Uni and RC feed the most, if not all, of scientific journals worldwide. By this I mean that is in the interest of Motricidade to be associated with high-quality RC and Uni equally recognized. With regard to RC, Motricidade will publish this year a supplement of the International Congress of Research Centre in Sports Sciences, Health Sciences and Human Development (CIDESD. This RC has conducted research in a variety of areas within the Sport Sciences and Health and always with high recognition and associated publications. It was not by chance that this RC was evaluated with ‘very good’ by the Portuguese Foundation for Science and Technology (FCT panel and has been granted funding. This Congress, which takes place every two years, targets to converge research and high level practices within these three areas: Sports, Health and Human Development. The 2016 CIDESD edition is dedicated to "Exercise and Health, Sports and Human Development" and will be held at the University of Évora, between 11 and 12 November of 2016. The readers can check the program in the following link http://gdoc.uevora.pt/450120 and get more information in the Congress Site available at http://www.cidesd2016.uevora.pt/. With regard to Uni, Motricidade signed a cooperation protocol with the University of Beira Interior (UBI in May of 2016, involving the development and dissemination of scientific knowledge in Sports Sciences, Psychology, Human Development and Health. At the present, UBI hosts more than 6,000 students spread across five faculties - Arts & Letters, Sciences, Health Sciences, Humanities and Social Sciences and Engineering. When looking at the rankings, for instance

  3. Applications of NMR in biological metabolic research

    International Nuclear Information System (INIS)

    Nie Jiarui; Li Xiuqin; He Chunjian

    1989-01-01

    The nuclear magnetic resonance has become a powerful means of studying biological metabolism in non-invasive and non-destructive way. Being used to study the metabolic processes of living system in normal physiological conditions as well as in molecular level, the method is better than other conventional approaches. Using important parameters such as NMR-chemical shifts, longitudinal relaxation time and transverse relaxation time, it is possible to probe the metabolic processes as well as conformation, concentration, transportation and distribution of reacting and resulting substances. The NMR spectroscopy of 1 H, 31 P and 13 C nuclei has already been widely used in metabolic researches

  4. Louisiana Transportation Research Center : Annual report, 2016-2017

    Science.gov (United States)

    2017-10-11

    This publication is a report of the transportation research, technology transfer, education, and training activities of the Louisiana Transportation Research Center for July 1, 2016 - June 30, 2017. The center is sponsored jointly by the Louisiana De...

  5. Synergy between medicinal chemistry and biological research.

    Science.gov (United States)

    Moncada, Salvador; Coaker, Hannah

    2014-09-01

    Salvador Moncada studied medicine at the University of El Salvador (El Salvador) before coming to the UK in 1971 to work on a PhD with Professor John Vane at the Institute of Basic Medical Sciences, Royal College of Surgeons (UK). After a short period of research at the University of Honduras (Honduras), he joined the Wellcome Research Laboratories (UK) where he became Head of the Department of Prostaglandin Research and later, Director of Research. He returned to academic life in 1996 as founder and director of the Wolfson Institute for Biomedical Research at University College London (UK). Moncada played a role in the discovery of the mechanism of action of aspirin-like drugs and later led the teams which discover prostacyclin and identified nitric oxide as a biological mediator. In his role as a Director of Research of the Wellcome Laboratories, he oversaw the discovery and development of medicines for epilepsy, migraine, malaria and cancer. Currently, he is working on the regulation of cell proliferation as Director of the Institute of Cancer Sciences at the University of Manchester (UK). Moncada has won numerous awards from the international scientific community and in 2010, he received a knighthood from Her Majesty Queen Elizabeth II for his services to science.

  6. Langley Research Center Strategic Plan for Education

    Science.gov (United States)

    Proctor, Sandra B.

    1994-01-01

    Research assignment centered on the preparation of final draft of the NASA Langley Strategic Plan for Education. Primary research activity consisted of data collection, through interviews with LaRC Office of Education and NASA Headquarters staff, university administrators and faculty, and school administrators / teachers; and documentary analysis. Pre-college and university programs were critically reviewed to assure effectiveness, support of NASA and Langley's mission and goals; National Education Goals; and educational reform strategies. In addition to these mandates, pre-college programs were reviewed to address present and future LaRC activities for teacher enhancement and preparation. University programs were reviewed with emphasis on student support and recruitment; faculty development and enhancement; and LaRC's role in promoting the utilization of educational technologies and distance learning. The LaRC Strategic Plan for Education will enable the Office of Education to provide a focused and well planned continuum of education programs for students, teachers and faculty. It will serve to direct and focus present activities and programs while simultaneously offering the flexibility to address new and emerging directions based on changing national, state, and agency trends.

  7. Center for Ecotoxicological Research of Montenegro

    International Nuclear Information System (INIS)

    Vucinic, Z.

    2006-01-01

    PI Center for Ecotoxicological Research of Montenegro (CETI) is founded 1996's in accordance with Government policy, for the purpose to: Unite the problems of protecting the environment in one institution, Organize the monitoring of the all segments of environment (air, waters soils, waste, ionizing and non-ionizing radiation, noise measurements etc.), Organize control of human and animal food and toxicological analysis of all kind of samples, forensic analyses etc. To concentrate the expensive instrumental equipment and human resources in one institution. December 1996 - CETI founded by decision of Montenegrin government 1997-CETI starting with acquisition of equipment and education of the staff March of 1998 - Officially starting with the job and realization with Program's September 2004 - Took the ISO 9001:2000 Certificate and Accreditation under ISO/IEC 17025 in November 2004 Organisation Scheme of CETI: Laboratory For Ecotoxicological Research And Radiation Protection I. Department For Laboratory Diagnostic And Monitoring II. Department For Radiation Protection And Monitoring Sector For Administration Department For Economy Department For Administration Total number of Employs is 63 of permanent staff

  8. Data acquisition and analysis at the Structural Biology Center

    International Nuclear Information System (INIS)

    Westbrook, M.L.; Coleman, T.A.; Daly, R.T.; Pflugrath, J.W.

    1996-01-01

    The Structural Biology Center (SBC), a national user facility for macromolecular crystallography located at Argonne National Laboratory's Advanced Photon Source, is currently being built and commissioned. SBC facilities include a bending-magnet beamline, an insertion-device beamline, laboratory and office space adjacent to the beamlines, and associated instrumentation, experimental apparatus, and facilities. SBC technical facilities will support anomalous dispersion phasing experiments, data collection from microcrystals, data collection from crystals with large molecular structures and rapid data collection from multiple related crystal structures for protein engineering and drug design. The SBC Computing Systems and Software Engineering Group is tasked with developing the SBC Control System, which includes computing systems, network, and software. The emphasis of SBC Control System development has been to provide efficient and convenient beamline control, data acquisition, and data analysis for maximal facility and experimenter productivity. This paper describes the SBC Control System development, specifically data acquisition and analysis at the SBC, and the development methods used to meet this goal

  9. Overview of Stirling Technology Research at NASA Glenn Research Center

    Science.gov (United States)

    Wilson, Scott D.; Schifer, Nicholas A.; Williams, Zachary D.; Metscher, Jonathan F.

    2016-01-01

    Stirling Radioisotope Power Systems (RPSs) are under development to provide power on future space science missions where robotic spacecraft will orbit, fly by, land, or rove using less than a quarter of the plutonium the currently available RPS uses to produce about the same power. NASA Glenn Research Center's newly formulated Stirling Cycle Technology Development Project (SCTDP) continues development of Stirling-based systems and subsystems, which include a flight-like generator and related housing assembly, controller, and convertors. The project also develops less mature technologies under Stirling Technology Research, with a focus on demonstration in representative environments to increase the technology readiness level (TRL). Matured technologies are evaluated for selection in future generator designs. Stirling Technology Research tasks focus on a wide variety of objectives, including increasing temperature capability to enable new environments, reducing generator mass and/or size, improving reliability and system fault tolerance, and developing alternative designs. The task objectives and status are summarized.

  10. Idaho National Laboratory - Nuclear Research Center

    International Nuclear Information System (INIS)

    Zaidi, M.K.

    2005-01-01

    Full text: The Idaho National Laboratory is committed to the providing international nuclear leadership for the 21st Century, developing and demonstrating compiling national security technologies, and delivering excellence in science and technology as one of the United States Department of Energy's (DOE) multiprogram national laboratories. INL runs three major programs - Nuclear, Security and Science. nuclear programs covers the Advanced test reactor, Six Generation technology concepts selected for R and D, Targeting tumors - Boron Neutron capture therapy. Homeland security - Homeland Security establishes the Control System Security and Test Center, Critical Infrastructure Test Range evaluates technologies on a scalable basis, INL conducts high performance computing and visualization research and science - INL facility established for Geocentrifuge Research, Idaho Laboratory, a Utah company achieved major milestone in hydrogen research and INL uses extremophile bacteria to ease bleaching's environmental cost. To provide leadership in the education and training, INL has established an Institute of Nuclear Science and Engineering (Inset). The institute will offer a four year degree based on a newly developed curriculum - two year of basic science course work and two years of participation in project planning and development. The students enrolled in this program can continue to get a masters or a doctoral degree. This summer Inset is the host for the training of the first international group selected by the World Nuclear University (WNU) - 75 fellowship holders and their 30 instructors from 40 countries. INL has been assigned to provide future global leadership in the field of nuclear science and technology. Here, at INL, we keep safety first above all things and our logo is 'Nuclear leadership synonymous with safety leadership'

  11. Applied Physics Research at the Idaho Accelerator Center

    International Nuclear Information System (INIS)

    Date, D. S.; Hunt, A. W.; Chouffani, K.; Wells, D. P.

    2011-01-01

    The Idaho Accelerator Center, founded in 1996 and based at Idaho State University, supports research, education, and high technology economic development in the United States. The research center currently has eight electron linear accelerators ranging in energy from 6 to 44 MeV with the latter linear accelerator capable of picosecond pulses, a 2 MeV positive-ion Van de Graaff, a 4 MV Nec tandem Pelletron, and a pulsed-power 8 k A, 10 MeV electron induction accelerator. Current research emphases include, accelerator physics research, accelerator based medical isotope production, active interrogation techniques for homeland security and nuclear nonproliferation applications, non destructive testing and materials science studies in support of industry as well as the development of advanced nuclear fuels, pure and applied radio-biology, and medical physics. This talk will highlight three of these areas including the production of the isotopes 99 Tc and 67 Cu for medical diagnostics and therapy, as well as two new technologies currently under development for nuclear safeguards and homeland security - namely laser Compton scattering and the polarized photofission of actinides

  12. Biological and Environmental Research Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Balaji, V. [Princeton Univ., NJ (United States). Earth Science Grid Federation (ESGF); Boden, Tom [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Cowley, Dave [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Dart, Eli [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Dattoria, Vince [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Desai, Narayan [Argonne National Lab. (ANL), Argonne, IL (United States); Egan, Rob [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Foster, Ian [Argonne National Lab. (ANL), Argonne, IL (United States); Goldstone, Robin [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gregurick, Susan [U.S. Dept. of Energy, Washington, DC (United States). Biological Systems Science Division; Houghton, John [U.S. Dept. of Energy, Washington, DC (United States). Biological and Environmental Research (BER) Program; Izaurralde, Cesar [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnston, Bill [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Joseph, Renu [U.S. Dept. of Energy, Washington, DC (United States). Climate and Environmental Sciences Division; Kleese-van Dam, Kerstin [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lipton, Mary [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Monga, Inder [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Pritchard, Matt [British Atmospheric Data Centre (BADC), Oxon (United Kingdom); Rotman, Lauren [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Strand, Gary [National Center for Atmospheric Research (NCAR), Boulder, CO (United States); Stuart, Cory [Argonne National Lab. (ANL), Argonne, IL (United States); Tatusova, Tatiana [National Inst. of Health (NIH), Bethesda, MD (United States); Tierney, Brian [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Thomas, Brian [Univ. of California, Berkeley, CA (United States); Williams, Dean N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Zurawski, Jason [Internet2, Washington, DC (United States)

    2013-09-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy (DOE) Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of SC programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet be a highly successful enabler of scientific discovery for over 25 years. In November 2012, ESnet and the Office of Biological and Environmental Research (BER) of the DOE SC organized a review to characterize the networking requirements of the programs funded by the BER program office. Several key findings resulted from the review. Among them: 1) The scale of data sets available to science collaborations continues to increase exponentially. This has broad impact, both on the network and on the computational and storage systems connected to the network. 2) Many science collaborations require assistance to cope with the systems and network engineering challenges inherent in managing the rapid growth in data scale. 3) Several science domains operate distributed facilities that rely on high-performance networking for success. Key examples illustrated in this report include the Earth System Grid Federation (ESGF) and the Systems Biology Knowledgebase (KBase). This report expands on these points, and addresses others as well. The report contains a findings section as well as the text of the case studies discussed at the review.

  13. 2010 Plant Molecular Biology Gordon Research Conference

    Energy Technology Data Exchange (ETDEWEB)

    Michael Sussman

    2010-07-23

    The Plant Molecular Biology Conference has traditionally covered a breadth of exciting topics and the 2010 conference will continue in that tradition. Emerging concerns about food security have inspired a program with three main themes: (1) genomics, natural variation and breeding to understand adaptation and crop improvement, (2) hormonal cross talk, and (3) plant/microbe interactions. There are also sessions on epigenetics and proteomics/metabolomics. Thus this conference will bring together a range of disciplines, will foster the exchange of ideas and enable participants to learn of the latest developments and ideas in diverse areas of plant biology. The conference provides an excellent opportunity for individuals to discuss their research because additional speakers in each session will be selected from submitted abstracts. There will also be a poster session each day for a two-hour period prior to dinner. In particular, this conference plays a key role in enabling students and postdocs (the next generation of research leaders) to mingle with pioneers in multiple areas of plant science.

  14. Division of Biological and Medical Research annual research summary, 1983

    Energy Technology Data Exchange (ETDEWEB)

    Barr, S.H. (ed.)

    1984-08-01

    This research summary contains brief descriptions of research in the following areas: (1) mechanisms of hepatocarcinogenesis; (2) role of metals in cocarcinogenesis and the use of liposomes for metal mobilization; (3) control of mutagenesis and cell differentiation in cultured cells by tumor promoters; (4) radiation effects in mammalian cells; (5) radiation carcinogenesis and radioprotectors; (6) life shortening, tumor induction, and tissue dose for fission-neutron and gamma-ray irradiations; (7) mammalian genetics and biostatistics; (8) radiation toxicity studies; (9) hematopoiesis in chronic toxicity; (10) molecular biology studies; (11) chemical toxicology; (12) carcinogen identification and metabolism; (13) metal metabolism and toxicity; and (14) neurobehavioral chronobiology. (ACR)

  15. Division of Biological and Medical Research annual research summary, 1983

    International Nuclear Information System (INIS)

    Barr, S.H.

    1984-08-01

    This research summary contains brief descriptions of research in the following areas: (1) mechanisms of hepatocarcinogenesis; (2) role of metals in cocarcinogenesis and the use of liposomes for metal mobilization; (3) control of mutagenesis and cell differentiation in cultured cells by tumor promoters; (4) radiation effects in mammalian cells; (5) radiation carcinogenesis and radioprotectors; (6) life shortening, tumor induction, and tissue dose for fission-neutron and gamma-ray irradiations; (7) mammalian genetics and biostatistics; (8) radiation toxicity studies; (9) hematopoiesis in chronic toxicity; (10) molecular biology studies; (11) chemical toxicology; (12) carcinogen identification and metabolism; (13) metal metabolism and toxicity; and (14) neurobehavioral chronobiology

  16. On-going research projects at Ankara Nuclear Research Center in Agriculture and Animal Science

    International Nuclear Information System (INIS)

    Tukenmez, I.

    2004-01-01

    Full text: The research and development activities of Ankara Nuclear Research Center in Agriculture and Animal Science(ANRCAA) are concentrated on the contribution of atomic energy to peace by the use of nuclear and related techniques in food, agriculture and animal science. Nuclear techniques are used in the above fields in two ways: in vitro or in vivo radio tracing the substances and processes of biological importance, and irradiation of biological materials for preservation and quality modification. Research projects are carried out by interdisciplinary studies with well equipped laboratories at the Center. The projects in progress conducted by the Center comprises nuclear-aided researches in soil fertility, plant nutrition, plant protection, improvement of field crops, improvement of horticultural plants and forest trees by mutation breeding, in vitro culture technique with mutagen treatments, use of phosphogypsum in soil amelioration, sterilization of medical supplies, wastewater treatment, animal nutrition, animal health and productivity and accreditation. The on-going projects with the above subjects will be summarized for possible collaborations

  17. On-going research projects at Ankara Nuclear research center in agriculture and animal science

    International Nuclear Information System (INIS)

    Tukenmez, I.

    2004-01-01

    Full text:The research and development activities of Ankara Nuclear Research Center in Agriculture and Animal Science(ANRCAA) are concentrated on the contribution of atomic energy to peace by the use of nuclear and related techniques in food, agriculture and animal science. Nuclear techniques are used in the above fields in two ways: in vitro or in vivo radio tracing the substances and processes of biological importance, and irradiation of biological materials for preservation and quality modification. Research projects are carried out by interdisciplinary studies with well equipped laboratories at the Center. The projects in progress conducted by the Center comprises nuclear-aided researches in soil fertility, plant nutrition, plant protection, improvement of field crops, improvement of horticultural plants and forest trees by mutation breeding, in vitro culture technique with mutagen treatments, use of phosphogypsum in soil amelioration, sterilization of medical supplies, wastewater treatment, animal nutrition, animal health and productivity and accreditation. The on-going projects with the above subjects will be summarized for possible collaborations

  18. Biological air contamination in elderly care centers: geria project.

    Science.gov (United States)

    Aguiar, Lívia; Mendes, Ana; Pereira, Cristiana; Neves, Paula; Mendes, Diana; Teixeira, João Paulo

    2014-01-01

    Indoor air quality (IAQ) affects health particularly in susceptible individuals such as the elderly. It has been estimated that the older population spends approximately 19-20 h/d indoors, and the majority of the elderly spend all of their time indoors in elderly care centers (ECC). Older individuals may be particularly at risk of exposure to detrimental effects from pollutants, even at low concentrations, due to common and multiple underlying chronic diseases that increase susceptibility. This study, aimed to assess the impact of indoor biological agents in 22 ECC located in Porto, was conducted during summer and winter from November 2011 to August 2013 at a total of 141 areas within dining rooms, drawing rooms, medical offices, and bedrooms (including the bedridden). Air sampling was carried out with a microbiological air sampler (Merck MAS-100) and using tryptic soy agar for bacteria and malt extract agar for fungi. The results obtained were compared with the recently revised Portuguese standards. In winter, mean fungi concentration exceeded reference values, while bacteria concentrations were within the new standards in both seasons. The main fungi species found indoors were Cladosporium (73%) in summer and Penicillium (67%) in winter. Aspergillus fumigatus, Aspergillus niger, and Aspergillus flavus, known potential pathogenic/toxigenic species, were also identified. Although the overall rate and mean values of bacteria and fungi found in ECC indoor air met Portuguese legislation, some concern is raised by the presence of pathogenic microorganisms. Simple measures, like opening windows and doors to promote air exchange and renewal, may improve effectiveness in enhancing IAQ.

  19. The Learning of Biology: A Structural Basis for Future Research

    Science.gov (United States)

    Murray, Darrel L.

    1977-01-01

    This article reviews recent research studies and experiences relating the learning theories of Ausubel to biology instruction. Also some suggestions are made for future research on the learning of biology. (MR)

  20. Molecular biology approaches in bioadhesion research

    Directory of Open Access Journals (Sweden)

    Marcelo Rodrigues

    2014-07-01

    Full Text Available The use of molecular biology tools in the field of bioadhesion is still in its infancy. For new research groups who are considering taking a molecular approach, the techniques presented here are essential to unravelling the sequence of a gene, its expression and its biological function. Here we provide an outline for addressing adhesion-related genes in diverse organisms. We show how to gradually narrow down the number of candidate transcripts that are involved in adhesion by (1 generating a transcriptome and a differentially expressed cDNA list enriched for adhesion-related transcripts, (2 setting up a BLAST search facility, (3 perform an in situ hybridization screen, and (4 functional analyses of selected genes by using RNA interference knock-down. Furthermore, latest developments in genome-editing are presented as new tools to study gene function. By using this iterative multi-technologies approach, the identification, isolation, expression and function of adhesion-related genes can be studied in most organisms. These tools will improve our understanding of the diversity of molecules used for adhesion in different organisms and these findings will help to develop innovative bio-inspired adhesives.

  1. Cooperative research with CHECIR (CHErnobyl Center for International Research)

    International Nuclear Information System (INIS)

    Nagaoka, T.; Saito, K.; Sakamoto, R.; Tsutsumi, M.; Moriuchi, S.

    1994-01-01

    The Chernobyl Center for International Research (CHECIR) has been established under an agreement among IAEA. Russia, Byelorussia and Ukraine in order to implement various studies on the reactor facilities and on the environment near and around the reactor. JAERI started discussions with a view to join the idea on the research project of study on assessment and analysis of environmental consequences in contaminated area. On June, 1992, JAERI and CHECIR concluded an agreement on the Implementation of Research at the CHECIR. Under the agreement, JAERI has started 'Study on Assessment and Analysis of Environmental Radiological Consequences and Verification of an Assessment System'. This project is scheduled to last until 1996. This study consists of following two subjects. Subject-1: Study on Measurements and Evaluation of Environmental External Exposure after Nuclear Accident. Subject-2: Study on the Validation of Assessment Models in an Environmental Consequence Assessment Methodology for Nuclear Accidents. Subject-3: Study on Migration of Radionuclides Released into Rivers adjacent to the Chernobyl Nuclear Power Plant (planned to start from FY1994). In this workshop, research activity will be introduced with actually measured data. (J.P.N.)

  2. Simbios: an NIH national center for physics-based simulation of biological structures.

    Science.gov (United States)

    Delp, Scott L; Ku, Joy P; Pande, Vijay S; Sherman, Michael A; Altman, Russ B

    2012-01-01

    Physics-based simulation provides a powerful framework for understanding biological form and function. Simulations can be used by biologists to study macromolecular assemblies and by clinicians to design treatments for diseases. Simulations help biomedical researchers understand the physical constraints on biological systems as they engineer novel drugs, synthetic tissues, medical devices, and surgical interventions. Although individual biomedical investigators make outstanding contributions to physics-based simulation, the field has been fragmented. Applications are typically limited to a single physical scale, and individual investigators usually must create their own software. These conditions created a major barrier to advancing simulation capabilities. In 2004, we established a National Center for Physics-Based Simulation of Biological Structures (Simbios) to help integrate the field and accelerate biomedical research. In 6 years, Simbios has become a vibrant national center, with collaborators in 16 states and eight countries. Simbios focuses on problems at both the molecular scale and the organismal level, with a long-term goal of uniting these in accurate multiscale simulations.

  3. Armstrong Flight Research Center Research Technology and Engineering 2017

    Science.gov (United States)

    Voracek, David F. (Editor)

    2018-01-01

    I am delighted to present this report of accomplishments at NASA's Armstrong Flight Research Center. Our dedicated innovators possess a wealth of performance, safety, and technical capabilities spanning a wide variety of research areas involving aircraft, electronic sensors, instrumentation, environmental and earth science, celestial observations, and much more. They not only perform tasks necessary to safely and successfully accomplish Armstrong's flight research and test missions but also support NASA missions across the entire Agency. Armstrong's project teams have successfully accomplished many of the nation's most complex flight research projects by crafting creative solutions that advance emerging technologies from concept development and experimental formulation to final testing. We are developing and refining technologies for ultra-efficient aircraft, electric propulsion vehicles, a low boom flight demonstrator, air launch systems, and experimental x-planes, to name a few. Additionally, with our unique location and airborne research laboratories, we are testing and validating new research concepts. Summaries of each project highlighting key results and benefits of the effort are provided in the following pages. Technology areas for the projects include electric propulsion, vehicle efficiency, supersonics, space and hypersonics, autonomous systems, flight and ground experimental test technologies, and much more. Additional technical information is available in the appendix, as well as contact information for the Principal Investigator of each project. I am proud of the work we do here at Armstrong and am pleased to share these details with you. We welcome opportunities for partnership and collaboration, so please contact us to learn more about these cutting-edge innovations and how they might align with your needs.

  4. Cellular Imaging | Center for Cancer Research

    Science.gov (United States)

    Innovative imaging methods developed and refined within CCR revealed atomic-level structures of biological molecules and unveiled dynamic views of a cell’s interior that are driving the design of new treatments and diagnostics for cancer.

  5. University of Kentucky Center for Applied Energy Research

    Science.gov (United States)

    University of Kentucky Center for Applied Energy Research Search Help Research Our Expertise University of Kentucky Center for Applied Energy Research | An Equal Opportunity University All Rights Remediation Power Generation CAER TechFacts CAER Factsheets CAER Affiliations Research Contacts Publications

  6. Fisher Center for Alzheimer's Research Foundation

    Science.gov (United States)

    ... Hear Kent Karosen, President and CEO of the Fisher Center, describe his new book and the power ... Signs of Alzheimer's Clinical Stages of Alzheimer’s About Fisher About Us Board of Trustees Financials Terms of ...

  7. Center Independent Research & Developments: JSC IRAD Program

    Data.gov (United States)

    National Aeronautics and Space Administration — JSC provides and applies its preeminent capabilities in science and technology to develop, operate, and integrate human exploration missions.  The center...

  8. The status of shielding research at Tajoura research center

    International Nuclear Information System (INIS)

    El-Bakkoush, F.A.

    2005-01-01

    This paper gives a description to the shielding research activities which have been carried-out at the radiation shielding group ,Tajoura Research Center. This includes the design of different types of concrete shields made from local aggregates which have suitable radiation attenuation properties. These include, Ordinary Concrete(with density p = 2.3 ton/m3) heavy weight concrete (with density p =3.6 ton/m3) and heat resistant concrete with aggregates having bound- in water. Investigation have been carried -out by measuring the neutron and gamma-rays spectra which have been transmitted through barriers having different thickness. These were performed using a collimated beam of reactor neutrons and gamma-ray transmitted from the horizontal channel no 1 of Tajoura-Research reactor with 10 MW Max ape rating power. The transmitted fast neutron and gamma spectra were measured by neutron-gamma spectrometer employing NE-213 liquid organic scintillater. Discrimination of against undesired pulses of neutrons or gamma-ray was achieved by a pulse shape discrimination method based on differences in the shape of the decay part of the emitted pulses. The obtained results are presented in the form of displayed neutron and gamma spectra measured behind different thickness of the investigated concrete shield. These spectra were used to derive the macroscopic cross section for at different energy for material under investigation

  9. Armstrong Flight Research Center Research Technology and Engineering Report 2015

    Science.gov (United States)

    Voracek, David F.

    2016-01-01

    I am honored to endorse the 2015 Neil A. Armstrong Flight Research Center’s Research, Technology, and Engineering Report. The talented researchers, engineers, and scientists at Armstrong are continuing a long, rich legacy of creating innovative approaches to solving some of the difficult problems and challenges facing NASA and the aerospace community.Projects at NASA Armstrong advance technologies that will improve aerodynamic efficiency, increase fuel economy, reduce emissions and aircraft noise, and enable the integration of unmanned aircraft into the national airspace. The work represented in this report highlights the Center’s agility to develop technologies supporting each of NASA’s core missions and, more importantly, technologies that are preparing us for the future of aviation and space exploration.We are excited about our role in NASA’s mission to develop transformative aviation capabilities and open new markets for industry. One of our key strengths is the ability to rapidly move emerging techniques and technologies into flight evaluation so that we can quickly identify their strengths, shortcomings, and potential applications.This report presents a brief summary of the technology work of the Center. It also contains contact information for the associated technologists responsible for the work. Don’t hesitate to contact them for more information or for collaboration ideas.

  10. Breast Cancer Translational Research Center of Excellence

    Science.gov (United States)

    2015-09-01

    CBCP) Breast Center is the Army-recognized and Military-recognized specialty referral center for t r i - se rv ice active duty personnel from around...development of customized treatment options in patients with HER2+ breast cancer. Objective 1 Evaluate differences in the molecular profiles of...2014CBCP & CCBB Analysis of Errors & Corrections 11/7/2014Customer Satisfaction Results Analysis 1/7/2015Audit of signed-out tissue samples in -80 freezer

  11. Aircraft Turbine Engine Control Research at NASA Glenn Research Center

    Science.gov (United States)

    Garg, Sanjay

    2014-01-01

    This lecture will provide an overview of the aircraft turbine engine control research at NASA (National Aeronautics and Space Administration) Glenn Research Center (GRC). A brief introduction to the engine control problem is first provided with a description of the current state-of-the-art control law structure. A historical aspect of engine control development since the 1940s is then provided with a special emphasis on the contributions of GRC. The traditional engine control problem has been to provide a means to safely transition the engine from one steady-state operating point to another based on the pilot throttle inputs. With the increased emphasis on aircraft safety, enhanced performance and affordability, and the need to reduce the environmental impact of aircraft, there are many new challenges being faced by the designers of aircraft propulsion systems. The Controls and Dynamics Branch (CDB) at GRC is leading and participating in various projects in partnership with other organizations within GRC and across NASA, other government agencies, the U.S. aerospace industry, and academia to develop advanced propulsion controls and diagnostics technologies that will help meet the challenging goals of NASA programs under the Aeronautics Research Mission. The second part of the lecture provides an overview of the various CDB technology development activities in aircraft engine control and diagnostics, both current and some accomplished in the recent past. The motivation for each of the research efforts, the research approach, technical challenges and the key progress to date are summarized. The technologies to be discussed include system level engine control concepts, gas path diagnostics, active component control, and distributed engine control architecture. The lecture will end with a futuristic perspective of how the various current technology developments will lead to an Intelligent and Autonomous Propulsion System requiring none to very minimum pilot interface

  12. Gifted and Talented Students' Views about Biology Activities in a Science and Art Center

    Science.gov (United States)

    Özarslan, Murat; Çetin, Gülcan

    2018-01-01

    The aim of the study was to determine gifted and talented students' views about biology activities in a science and art center. The study was conducted with 26 gifted and talented students who studied at a science and art center in southwestern Turkey. Students studied animal and plant genus and species in biology activities. Data were collected…

  13. Biological research for the radiation protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Chan Kug; Shim, Hae Won; Jung, Il Lae; Byun, Hee Sun; Moon, Myung Sook; Cho, Hye Jeong; Kim, Jin Sik

    2003-04-01

    The work scope of 'Biological Research for the Radiation Protection' had contained the research about polyamine effect on cell death triggered ionizing radiation, H 2 O 2 and toxic agents. In this paper, to elucidate the role of polyamines as mediator in lysosomal damage and stress(H 2 O 2 )- induced apoptosis, we utilized α-DiFluoroMethylOrnithine (DFMO), which inhibited ornithine decarboxylase and depleted intracellular putrescine, and investigated the effects of polyamine on the apoptosis caused by H 2 O 2 , ionizing radiation and paraquat. We also showed that MGBG, inhibitor of polyamine biosynthesis, treatment affected intracellular redox steady states, intracellular ROS levels and protein oxidation. Thereafter we also investigated whether MGBG may enhance the cytotoxic efficacy of tumor cells caused by ionizing radiation or H 2 O 2 because such compounds are able to potentiate the cell-killing effects. In addition, ceruloplasmin and thioredoxin, possible antioxidant proteins, were shown to have protective effect on radiation- or H 2 O 2 (or chemicals)-induced macromolecular damage or cell death

  14. Research progress on space radiation biology

    International Nuclear Information System (INIS)

    Li Wenjian; Dang Bingrong; Wang Zhuanzi; Wei Wei; Jing Xigang; Wang Biqian; Zhang Bintuan

    2010-01-01

    Space radiation, particularly induced by the high-energy charged particles, may cause serious injury on living organisms. So it is one critical restriction factor in Manned Spaceflight. Studies have shown that the biological effects of charged particles were associated with their quality, the dose and the different biological end points. In addition, the microgravity conditions may affect the biological effects of space radiation. In this paper we give a review on the biological damage effects of space radiation and the combined biological effects of the space radiation coupled with the microgravity from the results of space flight and ground simulation experiments. (authors)

  15. U.S. Department of Energy's Genomics: GTL Bioenergy Research Centers White Paper

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2006-08-01

    The Genomics:GTL Bioenergy Research Centers will be dedicated to fundamental research on microbe and plant systems with the goal of developing knowledge that will advance biotechnology-based strategies for biofuels production. The aim is to spur substantial progress toward cost-effective production of biologically based renewable energy sources. This document describes the rationale for the establishment of the centers and their objectives in light of the U.S. Department of Energy’s mission and goals.

  16. Radiation chemistry in development and research of radiation biology

    International Nuclear Information System (INIS)

    Min Rui

    2010-01-01

    During the establishment and development of radiation biology, radiation chemistry acts like bridge which units the spatial and temporal insight coming from radiation physics with radiation biology. The theory, model, and methodology of radiation chemistry play an important role in promoting research and development of radiation biology. Following research development of radiation biology effects towards systems radiation biology the illustration and exploration both diversity of biological responses and complex process of biological effect occurring remain to need the theory, model, and methodology come from radiation chemistry. (authors)

  17. Wave Energy Research, Testing and Demonstration Center

    Energy Technology Data Exchange (ETDEWEB)

    Batten, Belinda [Oregon State Univ., Corvallis, OR (United States)

    2014-09-30

    The purpose of this project was to build upon the research, development and testing experience of the Northwest National Marine Renewable Energy Center (NNMREC) to establish a non-grid connected open-ocean testing facility for wave energy converters (WECs) off the coast of Newport, Oregon. The test facility would serve as the first facility of its kind in the continental US with a fully energetic wave resource where WEC technologies could be proven for west coast US markets. The test facility would provide the opportunity for self-contained WEC testing or WEC testing connected via an umbilical cable to a mobile ocean test berth (MOTB). The MOTB would act as a “grid surrogate” measuring energy produced by the WEC and the environmental conditions under which the energy was produced. In order to realize this vision, the ocean site would need to be identified through outreach to community stakeholders, and then regulatory and permitting processes would be undertaken. Part of those processes would require environmental baseline studies and site analysis, including benthic, acoustic and wave resource characterization. The MOTB and its myriad systems would need to be designed and constructed.The first WEC test at the facility with the MOTB was completed within this project with the WET-NZ device in summer 2012. In summer 2013, the MOTB was deployed with load cells on its mooring lines to characterize forces on mooring systems in a variety of sea states. Throughout both testing seasons, studies were done to analyze environmental effects during testing operations. Test protocols and best management practices for open ocean operations were developed. As a result of this project, the non-grid connected fully energetic WEC test facility is operational, and the MOTB system developed provides a portable concept for WEC testing. The permitting process used provides a model for other wave energy projects, especially those in the Pacific Northwest that have similar

  18. Juelich Research Center. Annual report 1991

    International Nuclear Information System (INIS)

    1991-10-01

    The Research Centre Juelich (KFA) as one of the thirteen national research centres in the Federal Republic of Germany is probably unique in that it concentrates equally on four essentials for mankind - energy, health and environment, materials and matter as well as information. These basic requirements are reflected by the four priority programmes characterizing research at the KFA in the nineties. The research priorities are: Properties of Matter and Material Research; Basic Research on Information Technology; Health, Environment, Biotechnology; Energy Research and Technology; Nuclear Fusion; Basic Nuclear Research; Interdisciplinary Analyses and Methods. (orig./HSCH) [de

  19. Bastyr/UW Oncomycology Translational Research Center

    Data.gov (United States)

    Federal Laboratory Consortium — Research Area: FungiProgram: Partnerships for CAM Clinical Translational ResearchDescription:Trametes versicolor is an immunologically active medicinal mushroom that...

  20. Has Modern Biology Entered the Mouth? The Clinical Impact of Biological Research.

    Science.gov (United States)

    Baum, Bruce J.

    1991-01-01

    Three areas of biological research that are beginning to have an impact on clinical medicine are examined, including molecular biology, cell biology, and biotechnology. It is concluded that oral biologists and educators must work cooperatively to bring rapid biological and biomedical advances into dental training in a meaningful way. (MSE)

  1. Earth Radiation Budget Research at the NASA Langley Research Center

    Science.gov (United States)

    Smith, G. Louis; Harrison, Edwin F.; Gibson, Gary G.

    2014-01-01

    In the 1970s research studies concentrating on satellite measurements of Earth's radiation budget started at the NASA Langley Research Center. Since that beginning, considerable effort has been devoted to developing measurement techniques, data analysis methods, and time-space sampling strategies to meet the radiation budget science requirements for climate studies. Implementation and success of the Earth Radiation Budget Experiment (ERBE) and the Clouds and the Earth's Radiant Energy System (CERES) was due to the remarkable teamwork of many engineers, scientists, and data analysts. Data from ERBE have provided a new understanding of the effects of clouds, aerosols, and El Nino/La Nina oscillation on the Earth's radiation. CERES spacecraft instruments have extended the time coverage with high quality climate data records for over a decade. Using ERBE and CERES measurements these teams have created information about radiation at the top of the atmosphere, at the surface, and throughout the atmosphere for a better understanding of our climate. They have also generated surface radiation products for designers of solar power plants and buildings and numerous other applications

  2. Physician Assistant | Center for Cancer Research

    Science.gov (United States)

    counseling within the boundaries of his/her specialty area of education and clinical preparation (pediatrics, adults, urologic, surgical, etc.). Review assigned patient resident reports and carry and answer the resident pager. Provide coverage for the post-call resident’s patients, while working closely with the Inpatient/Fellowship staff.  Support in-patient and out-patient care of subjects enrolled in experimental protocols and clinical trials. Work as a member of a multidisciplinary clinical team to provide comprehensive care to patients in a research environment. Write prescriptions. Explain the care management/discharge plan to all members of the covering team (inpatient NPs, attendings) at signout. This position is located in Bethesda, Maryland in support of the Center for Cancer Research (CCR).

  3. Quality Control Specialist | Center for Cancer Research

    Science.gov (United States)

    Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID),

  4. Multi-Institution Research Centers: Planning and Management Challenges

    Science.gov (United States)

    Spooner, Catherine; Lavey, Lisa; Mukuka, Chilandu; Eames-Brown, Rosslyn

    2016-01-01

    Funding multi-institution centers of research excellence (CREs) has become a common means of supporting collaborative partnerships to address specific research topics. However, there is little guidance for those planning or managing a multi-institution CRE, which faces specific challenges not faced by single-institution research centers. We…

  5. Naval Health Research Center 1985 Annual Report

    Science.gov (United States)

    1985-01-01

    strengthening programs for the entire crew. Aerobic programs for select populations (e.g., overweight personnel), however, were found on 20% of the...Institute, Lima Detachment, Peru (Command) 25-26 UCOR R. Kallal, CUP W. J. Lambert, & M. Nave, Naval Data Services Center, Bethesda, Maryland (Dr

  6. Veterinary Oncologist | Center for Cancer Research

    Science.gov (United States)

    The NCI is implementing a program intended to connect and closely coordinate the Division of Cancer Treatment and Diagnosis’ (DCTD’s) immunotherapeutics and other drug development activities with the translational oriented clinical trials of the Center for Cancer Research’s (CCR’s) Comparative Oncology Program (COP), especially the treatment of dogs with natural occurring

  7. NASA Langley Research Center outreach in astronautical education

    Science.gov (United States)

    Duberg, J. E.

    1976-01-01

    The Langley Research Center has traditionally maintained an active relationship with the academic community, especially at the graduate level, to promote the Center's research program and to make graduate education available to its staff. Two new institutes at the Center - the Joint Institute for Acoustics and Flight Sciences, and the Institute for Computer Applications - are discussed. Both provide for research activity at the Center by university faculties. The American Society of Engineering Education Summer Faculty Fellowship Program and the NASA-NRC Postdoctoral Resident Research Associateship Program are also discussed.

  8. University of Washington Center for Child Environmental Health Risks Research

    Data.gov (United States)

    Federal Laboratory Consortium — The theme of the University of Washington based Center for Child Environmental Health Risks Research (CHC) is understanding the biochemical, molecular and exposure...

  9. pClone: Synthetic Biology Tool Makes Promoter Research Accessible to Beginning Biology Students

    Science.gov (United States)

    Campbell, A. Malcolm; Eckdahl, Todd; Cronk, Brian; Andresen, Corinne; Frederick, Paul; Huckuntod, Samantha; Shinneman, Claire; Wacker, Annie; Yuan, Jason

    2014-01-01

    The "Vision and Change" report recommended genuine research experiences for undergraduate biology students. Authentic research improves science education, increases the number of scientifically literate citizens, and encourages students to pursue research. Synthetic biology is well suited for undergraduate research and is a growing area…

  10. Center for oceanographic research opens in Chile

    Science.gov (United States)

    Lange, Carina B.; Ulloa, Osvaldo

    The Humboldt Current System, with its coastal upwelling ecosystem off Peru and Chile, is one of the most productive marine systems in the world. Here, significant exchange of heat and CO2 takes place between the ocean and the atmosphere due to upwelling of sub-surface, cold, nutrient-rich, CO2-saturated waters. In addition, the eastern South Pacific holds one of the three most important oxygen minimum zones of the global ocean. Through the biologically mediated process of denitrification, the oxygen minimum zone contributes to the global sink of nitrogen in the ocean and as a source of the greenhouse gas N2O to the atmosphere.

  11. Plant biology research and training for the 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, K. [ed.

    1992-12-31

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  12. Plant biology research and training for the 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, K. (ed.)

    1992-01-01

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  13. U.S. DAIRY FORAGE RESEARCH CENTER

    Data.gov (United States)

    Federal Laboratory Consortium — Vision: Leading the world in integrated dairy forage systems research. Mission: Providing dairy industry solutions for food security, environmental sustainability,...

  14. University of Maryland Energy Research Center |

    Science.gov (United States)

    breakthroughs into commercial, clean energy solutions. The Clark School Celebrates Women's History Month The Clark School is featuring our female engineering faculty members throughout March. UMD Researchers

  15. U.S. Dairy Forage Research Center

    Data.gov (United States)

    Federal Laboratory Consortium — Vision: Leading the world in integrated dairy forage systems research. Mission: Providing dairy industry solutions for food security, environmental sustainability,...

  16. Fusion Research Center, theory program. Progress report

    International Nuclear Information System (INIS)

    1982-01-01

    The Texas FRC theory program is directed primarily toward understanding the initiation, heating, and confinement of tokamak plasmas. It supports and complements the experimental programs on the TEXT and PRETEXT devices, as well as providing information generally applicable to the national tokamak program. A significant fraction of the Center's work has been carried out in collaboration with, or as a part of, the program of the Institute for Fusion Studies (IFS). During the past twelve months, 14 FRC theory reports and 12 IFS reports with partial FRC support have been issued

  17. Postharvest biology and technology research and development ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-09-03

    Sep 3, 2008 ... The applications of biological control agents in pre- and post-harvest operations and .... production, with regards to food safety, operator health and the ... and to work out sustainable compliance modalities for small-scale ...

  18. Laboratory Animal Technician | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

  19. Communications Specialist | Center for Cancer Research

    Science.gov (United States)

    Be part of our mission to support research against cancer. We have an exciting opportunity for a talented communicator to join our team and be part of the effort to find cures for cancer. We are looking for a creative, team-oriented communications professional, with strong writing skills to publicize our research advances, employment and training opportunities and clinical

  20. NASA Lewis Research Center's materials and structures division

    International Nuclear Information System (INIS)

    Weymueller, C.R.

    1976-01-01

    Research activities at the NASA Lewis Research Center on materials and structures are discussed. Programs are noted on powder metallurgy superalloys, eutectic alloys, dispersion strengthened alloys and composite materials. Discussions are included on materials applications, coatings, fracture mechanics, and fatigue

  1. STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)

    International Nuclear Information System (INIS)

    Eisenberg, David S.

    2008-01-01

    The UCLA-DOE Institute of Genomics and Proteomics is an organized research unit of the University of California, sponsored by the Department of Energy through the mechanism of a Cooperative Agreement. Today the Institute consists of 10 Principal Investigators and 7 Associate Members, developing and applying technologies to promote the biological and environmental missions of the Department of Energy, and 5 Core Technology Centers to sustain this work. The focus is on understanding genomes, pathways and molecular machines in organisms of interest to DOE, with special emphasis on developing enabling technologies. Since it was founded in 1947, the UCLA-DOE Institute has adapted its mission to the research needs of DOE and its progenitor agencies as these research needs have changed. The Institute started as the AEC Laboratory of Nuclear Medicine, directed by Stafford Warren, who later became the founding Dean of the UCLA School of Medicine. In this sense, the entire UCLA medical center grew out of the precursor of our Institute. In 1963, the mission of the Institute was expanded into environmental studies by Director Ray Lunt. I became the third director in 1993, and in close consultation with David Galas and John Wooley of DOE, shifted the mission of the Institute towards genomics and proteomics. Since 1993, the Principal Investigators and Core Technology Centers are entirely new, and the Institute has separated from its former division concerned with PET imaging. The UCLA-DOE Institute shares the space of Boyer Hall with the Molecular Biology Institute, and assumes responsibility for the operation of the main core facilities. Fig. 1 gives the organizational chart of the Institute. Some of the benefits to the public of research carried out at the UCLA-DOE Institute include the following: The development of publicly accessible, web-based databases, including the Database of Protein Interactions, and the ProLinks database of genomicly inferred protein function linkages

  2. Radiation protection in biological investigation centers. Problematic, development and perspectives

    International Nuclear Information System (INIS)

    Macias, M.T.; Pina, R.; Usera, F.

    1998-01-01

    The radiological risk derivatives from the radioisotope techniques accomplished in the different investigation lines developed in the Centers object of this work, have necessary made establishing an organization that assure some adequate protection conditions in the use of the ionizing radiations

  3. Annual report of the Management Research Center

    International Nuclear Information System (INIS)

    1987-01-01

    Research on the management of new forms of automation; industrial management; the definition of a new product range; economic management; personnel management; and management of cultural enterprises is presented [fr

  4. Center for Cold Spray Research and Development

    Data.gov (United States)

    Federal Laboratory Consortium — This is the only DoD facility capable of cold spray research and development, production, and field-repair. It features three stationary cold spray systems used for...

  5. Team Members | Center for Cancer Research

    Science.gov (United States)

    Our Team Members The Foregut Team includes experts in the diagnosis and treatment of the diseases listed below. Our clinical experience and active research offers patients the highest quality care in the setting of groundbreaking clinical trials.

  6. A National Coordinating Center for Trauma Research

    Science.gov (United States)

    2016-10-01

    subcommittee. Several existing platforms have been reviewed in-depth with online demonstrations (such as Research Electronic Data Capture (REDCap), FITBIR...to maximize its ability to advertise the existence of data, promote re-use and assist in data management. It is interesting to note that: Most...just as ethics forms are normal for many now. We present two scenarios here: one when a grant starts, and the researcher is prompted to finish and

  7. Breast Cancer Translational Research Center of Excellence

    Science.gov (United States)

    2017-11-01

    FACS, COL MC USA CONTRACTING ORGANIZATION: Henry M. Jackson Foundation for the Advancement of Military Medicine 6720-A Rockledge Drive Bethesda...reported to other officials or ethically requires action, e.g., child or spouse abuse ii. When will you destroy the research source documents, data file...requires to be reported to other officials or ethically requires action, e.g., child or spouse abuse When will you destroy the research source documents

  8. The National Center for Atmospheric Research (NCAR) Research Data Archive: a Data Education Center

    Science.gov (United States)

    Peng, G. S.; Schuster, D.

    2015-12-01

    The National Center for Atmospheric Research (NCAR) Research Data Archive (RDA), rda.ucar.edu, is not just another data center or data archive. It is a data education center. We not only serve data, we TEACH data. Weather and climate data is the original "Big Data" dataset and lessons learned while playing with weather data are applicable to a wide range of data investigations. Erroneous data assumptions are the Achilles heel of Big Data. It doesn't matter how much data you crunch if the data is not what you think it is. Each dataset archived at the RDA is assigned to a data specialist (DS) who curates the data. If a user has a question not answered in the dataset information web pages, they can call or email a skilled DS for further clarification. The RDA's diverse staff—with academic training in meteorology, oceanography, engineering (electrical, civil, ocean and database), mathematics, physics, chemistry and information science—means we likely have someone who "speaks your language." Data discovery is another difficult Big Data problem; one can only solve problems with data if one can find the right data. Metadata, both machine and human-generated, underpin the RDA data search tools. Users can quickly find datasets by name or dataset ID number. They can also perform a faceted search that successively narrows the options by user requirements or simply kick off an indexed search with a few words. Weather data formats can be difficult to read for non-expert users; it's usually packed in binary formats requiring specialized software and parameter names use specialized vocabularies. DSs create detailed information pages for each dataset and maintain lists of helpful software, documentation and links of information around the web. We further grow the level of sophistication of the users with tips, tutorials and data stories on the RDA Blog, http://ncarrda.blogspot.com/. How-to video tutorials are also posted on the NCAR Computational and Information Systems

  9. Proton Therapy Research and Treatment Center

    Energy Technology Data Exchange (ETDEWEB)

    Goodnight, J.E. Jr. (University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center); Alonso, J.R. (Lawrence Berkeley Lab., CA (United States))

    1992-05-01

    This Grant proposal outlines the steps that will be undertaken to bring the UC Davis Proton Therapy Research and Treatment, known locally as the Proton Therapy Facility (PTF), through its design and construction phases. This application concentrates on the design phase of the PTF project.

  10. Animal Resource Program | Center for Cancer Research

    Science.gov (United States)

    CCR Animal Resource Program The CCR Animal Resource Program plans, develops, and coordinates laboratory animal resources for CCR’s research programs. We also provide training, imaging, and technology development in support of moving basic discoveries to the clinic. The ARP Manager:

  11. Writing Essentials | Center for Cancer Research

    Science.gov (United States)

    To effectively communicate research results, the manuscript should be carefully structured to tell a compelling story. As a rule, the introduction should bring the reader from a broad understanding of the topic to the specific question being addressed. In contrast, the discussion should transition the reader from the specific results to their broader implications.

  12. Animal Resource Program | Center for Cancer Research

    Science.gov (United States)

    CCR Animal Resource Program The CCR Animal Resource Program plans, develops, and coordinates laboratory animal resources for CCR’s research programs. We also provide training, imaging, and technology development in support of moving basic discoveries to the clinic. The ARP Office:

  13. The prevention research centers' managing epilepsy well network.

    Science.gov (United States)

    DiIorio, Colleen K; Bamps, Yvan A; Edwards, Ariele L; Escoffery, Cam; Thompson, Nancy J; Begley, Charles E; Shegog, Ross; Clark, Noreen M; Selwa, Linda; Stoll, Shelley C; Fraser, Robert T; Ciechanowski, Paul; Johnson, Erica K; Kobau, Rosemarie; Price, Patricia H

    2010-11-01

    The Managing Epilepsy Well (MEW) Network was created in 2007 by the Centers for Disease Control and Prevention's (CDC) Prevention Research Centers and Epilepsy Program to promote epilepsy self-management research and to improve the quality of life for people with epilepsy. MEW Network membership comprises four collaborating centers (Emory University, University of Texas Health Science Center at Houston, University of Michigan, and University of Washington), representatives from CDC, affiliate members, and community stakeholders. This article describes the MEW Network's background, mission statement, research agenda, and structure. Exploratory and intervention studies conducted by individual collaborating centers are described, as are Network collaborative projects, including a multisite depression prevention intervention and the development of a standard measure of epilepsy self-management. Communication strategies and examples of research translation programs are discussed. The conclusion outlines the Network's role in the future development and dissemination of evidence-based epilepsy self-management programs. Copyright © 2010 Elsevier Inc. All rights reserved.

  14. A Community - Centered Astronomy Research Program

    Science.gov (United States)

    Boyce, Pat; Boyce, Grady

    2017-06-01

    The Boyce Research Initiatives and Education Foundation (BRIEF) is providing semester-long, hands-on, astronomy research experiences for students of all ages that results in their publishing peer-reviewed papers. The course in astronomy and double star research has evolved from a face-to-face learning experience with two instructors to an online - hybrid course that simultaneously supports classroom instruction at a variety of schools in the San Diego area. Currently, there are over 65 students enrolled in three community colleges, seven high schools, and one university as well as individual adult learners. Instructional experience, courseware, and supporting systems were developed and refined through experience gained in classroom settings from 2014 through 2016. Topics of instruction include Kepler's Laws, basic astrometry, properties of light, CCD imaging, use of filters for varying stellar spectral types, and how to perform research, scientific writing, and proposal preparation. Volunteer instructors were trained by taking the course and producing their own research papers. An expanded program was launched in the fall semester of 2016. Twelve papers from seven schools were produced; eight have been accepted for publication by the Journal of Double Observations (JDSO) and the remainder are in peer review. Three additional papers have been accepted by the JDSO and two more are in process papers. Three college professors and five advanced amateur astronomers are now qualified volunteer instructors. Supporting tools are provided by a BRIEF server and other online services. The server-based tools range from Microsoft Office and planetarium software to top-notch imaging programs and computational software for data reduction for each student team. Observations are performed by robotic telescopes worldwide supported by BRIEF. With this success, student demand has increased significantly. Many of the graduates of the first semester course wanted to expand their

  15. The effect of student-centered and teacher-centered instruction with and without conceptual advocacy on biology students' misconceptions, achievement, attitudes toward science, and cognitive retention

    Science.gov (United States)

    Gallop, Roger Graham

    The purpose of this study was to investigate the effect of student-centered and teacher-centered instructional strategies with and without conceptual advocacy (CA) on ninth-grade biology students' misconceptions (MIS), biology achievement (ACH), attitudes toward science (ATT), and cognitive retention of scientific method and measurement, spontaneous generation, and characteristics of living things. Students were purposively selected using intact classes and assigned to one of four treatment groups (i.e., student-centered instruction without CA, student-centered instruction with CA, teacher-centered instruction with CA, and teacher-centered instruction without CA). A modified quasi-experimental design was used in which students were not matched in the conventional sense but instead, groups were shown to be equivalent on the dependent measure via a pretest. A 5-day treatment implementation period addressed science conceptions under investigation. The treatment period was based on the number of class periods teachers at the target school actually spend teaching the biological concepts under investigation using traditional instruction. At the end of the treatment period, students were posttested using the Concepts in Biology instrument and Science Questionnaire. Eight weeks after the posttest, these instruments were administered again as a delayed posttest to determine cognitive retention of the correct biological conceptions and attitudes toward science. MANCOVA and follow-up univariate ANCOVA results indicated that student-centered instruction without CA (i.e., Group 1) did not have a significant effect on students' MIS, ACH, and ATT (F = .029, p = .8658; F = .002, p =.9688, F = .292, p = .5897, respectively). On the other hand, student-centered instruction with CA (i.e., Group 2) had a significant effect on students' MIS and ACH (F =10.33, p = .0016 and F = 10.17, p = .0017, respectively), but did not on ATT (F = .433, p = .5117). Teacher-centered instruction with

  16. Diseño de una estrategia integral para la gestión de la investigación en el Centro de Inmunología y Productos Biológicos de Camagüey An integrated strategy design for managing research at Camagüey's Center of Immunology and Biological Products

    Directory of Open Access Journals (Sweden)

    Imilla Casado Hernández

    2009-12-01

    centers connected to universities. This paper presents the design of an Integrated Strategy to properly include the Center of Immunology and Biological Products in the research activity of Camagüey's Medical School. It also includes a theoretical approach of research management to fully carry out the demands of practice. This research center should become an active institution promoting change from the inside through connections that most likely cause changes in the external environment.

  17. Research & Technology Report Goddard Space Flight Center

    Science.gov (United States)

    Soffen, Gerald A. (Editor); Truszkowski, Walter (Editor); Ottenstein, Howard (Editor); Frost, Kenneth (Editor); Maran, Stephen (Editor); Walter, Lou (Editor); Brown, Mitch (Editor)

    1995-01-01

    The main theme of this edition of the annual Research and Technology Report is Mission Operations and Data Systems. Shifting from centralized to distributed mission operations, and from human interactive operations to highly automated operations is reported. The following aspects are addressed: Mission planning and operations; TDRSS, Positioning Systems, and orbit determination; hardware and software associated with Ground System and Networks; data processing and analysis; and World Wide Web. Flight projects are described along with the achievements in space sciences and earth sciences. Spacecraft subsystems, cryogenic developments, and new tools and capabilities are also discussed.

  18. Bolivia. The new nuclear research center in El Alto

    International Nuclear Information System (INIS)

    Nogarin, Mauro

    2016-01-01

    Research reactors in Latin America have become a priority in public policy in the last decade. Bolivia wants to become the 8th country to implement peaceful nuclear technology in this area with the new Center for Research and Development in the Nuclear Technology. The Center will be the most advanced in Latin America. It will provide for a wide use of radiation technologies in agriculture, medicine, and industry. After several negotiations Bolivia and the Russian Federation signed the Intergovernmental Agreement on cooperation in the peaceful use of atomic energy and the construction of the Nuclear Research and Technology Center.

  19. Bolivia. The new nuclear research center in El Alto

    Energy Technology Data Exchange (ETDEWEB)

    Nogarin, Mauro

    2016-05-15

    Research reactors in Latin America have become a priority in public policy in the last decade. Bolivia wants to become the 8th country to implement peaceful nuclear technology in this area with the new Center for Research and Development in the Nuclear Technology. The Center will be the most advanced in Latin America. It will provide for a wide use of radiation technologies in agriculture, medicine, and industry. After several negotiations Bolivia and the Russian Federation signed the Intergovernmental Agreement on cooperation in the peaceful use of atomic energy and the construction of the Nuclear Research and Technology Center.

  20. Research Collaboration Workshop for Women in Mathematical Biology

    CERN Document Server

    Miller, Laura

    2017-01-01

    Inspired by the Research Collaboration Workshop for Women in Mathematical Biology, this volume contains research and review articles that cover topics ranging from models of animal movement to the flow of blood cells in the embryonic heart. Hosted by the National Institute for Mathematics and Biological Synthesis (NIMBioS), the workshop brought together women working in biology and mathematics to form four research groups that encouraged multidisciplinary collaboration and lifetime connections in the STEM field. This volume introduces many of the topics from the workshop, including the aerodynamics of spider ballooning; sleep, circadian rhythms, and pain; blood flow regulation in the kidney; and the effects of antimicrobial therapy on gut microbiota and microbiota and Clostridium difficile. Perfect for students and researchers in mathematics and biology, the papers included in this volume offer an introductory glimpse at recent research in mathematical biology. .

  1. A Case Study Documenting the Process by Which Biology Instructors Transition from Teacher-Centered to Learner-Centered Teaching

    Science.gov (United States)

    Marbach-Ad, Gili; Hunt Rietschel, Carly

    2016-01-01

    In this study, we used a case study approach to obtain an in-depth understanding of the change process of two university instructors who were involved with redesigning a biology course. Given the hesitancy of many biology instructors to adopt evidence-based, learner-centered teaching methods, there is a critical need to understand how biology instructors transition from teacher-centered (i.e., lecture-based) instruction to teaching that focuses on the students. Using the innovation-decision model for change, we explored the motivation, decision-making, and reflective processes of the two instructors through two consecutive, large-enrollment biology course offerings. Our data reveal that the change process is somewhat unpredictable, requiring patience and persistence during inevitable challenges that arise for instructors and students. For example, the change process requires instructors to adopt a teacher-facilitator role as opposed to an expert role, to cover fewer course topics in greater depth, and to give students a degree of control over their own learning. Students must adjust to taking responsibility for their own learning, working collaboratively, and relinquishing the anonymity afforded by lecture-based teaching. We suggest implications for instructors wishing to change their teaching and administrators wishing to encourage adoption of learner-centered teaching at their institutions. PMID:27856550

  2. Grand Canyon Monitoring and Research Center

    Science.gov (United States)

    Hamill, John F.

    2009-01-01

    The Grand Canyon of the Colorado River, one of the world's most spectacular gorges, is a premier U.S. National Park and a World Heritage Site. The canyon supports a diverse array of distinctive plants and animals and contains cultural resources significant to the region's Native Americans. About 15 miles upstream of Grand Canyon National Park sits Glen Canyon Dam, completed in 1963, which created Lake Powell. The dam provides hydroelectric power for 200 wholesale customers in six western States, but it has also altered the Colorado River's flow, temperature, and sediment-carrying capacity. Over time this has resulted in beach erosion, invasion and expansion of nonnative species, and losses of native fish. Public concern about the effects of Glen Canyon Dam operations prompted the passage of the Grand Canyon Protection Act of 1992, which directs the Secretary of the Interior to operate the dam 'to protect, mitigate adverse impacts to, and improve values for which Grand Canyon National Park and Glen Canyon National Recreation Area were established...' This legislation also required the creation of a long-term monitoring and research program to provide information that could inform decisions related to dam operations and protection of downstream resources.

  3. Postdoctoral Fellow | Center for Cancer Research

    Science.gov (United States)

    Dr. St. Croix’s laboratory at the Mouse Cancer Genetics Program (MCGP), National Cancer Institute, USA has an open postdoctoral position. We seek a highly motivated, creative and bright individual to participate in a collaborative project that involves the targeting of tumor-associated stroma using T-cells engineered to express chimeric antigen receptors (CARs). The laboratory focuses on the characterization and exploitation of molecules associated with tumor angiogenesis. The successful candidate would be involved in developing, producing and characterizing new therapeutic antibodies and CARs that recognize cancer cells or its associated stroma, and preclinical testing of these agents using mouse tumor models. The tumor angiogenesis lab is located at the National Cancer Institute in Frederick with access to state-of-the-art facilities for antibody engineering, genomic analysis, pathology, and small animal imaging, among others. Detailed information about Dr. St. Croix’s research and publications can be accessed at https://ccr.cancer.gov/Mouse-Cancer-Genetics-Program/brad-st-croix.

  4. Karlsruhe Nuclear Research Center. Research and development program 1991

    International Nuclear Information System (INIS)

    1990-01-01

    The R and D activities of the KfK are classified in 8 main research activities: 1) project nuclear fusion; 2) project pollutant mitigation in the environment; 3) solid state and materials research; 4) nuclear and elementary particle physics; 5) microtechnics e.g. X-ray lithography; 6) materials handling; 7) project nuclear safety research; 8) radioactive waste management. (orig.) [de

  5. A Case Study Documenting the Process by Which Biology Instructors Transition from Teacher-Centered to Learner-Centered Teaching.

    Science.gov (United States)

    Marbach-Ad, Gili; Hunt Rietschel, Carly

    2016-01-01

    In this study, we used a case study approach to obtain an in-depth understanding of the change process of two university instructors who were involved with redesigning a biology course. Given the hesitancy of many biology instructors to adopt evidence-based, learner-centered teaching methods, there is a critical need to understand how biology instructors transition from teacher-centered (i.e., lecture-based) instruction to teaching that focuses on the students. Using the innovation-decision model for change, we explored the motivation, decision-making, and reflective processes of the two instructors through two consecutive, large-enrollment biology course offerings. Our data reveal that the change process is somewhat unpredictable, requiring patience and persistence during inevitable challenges that arise for instructors and students. For example, the change process requires instructors to adopt a teacher-facilitator role as opposed to an expert role, to cover fewer course topics in greater depth, and to give students a degree of control over their own learning. Students must adjust to taking responsibility for their own learning, working collaboratively, and relinquishing the anonymity afforded by lecture-based teaching. We suggest implications for instructors wishing to change their teaching and administrators wishing to encourage adoption of learner-centered teaching at their institutions. © 2016 G. Marbach-Ad and C. H. Rietschel. CBE—Life Sciences Education © 2016 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  6. Physical Measurement Profile at Gilgel Gibe Field Research Center ...

    African Journals Online (AJOL)

    Physical Measurement Profile at Gilgel Gibe Field Research Center, ... hip circumference in under 35 years and body mass index in under 45 year age groups were ... Comparison with findings in other parts of the world showed that Ethiopians ...

  7. Small UAS Test Area at NASA's Dryden Flight Research Center

    Science.gov (United States)

    Bauer, Jeffrey T.

    2008-01-01

    This viewgraph presentation reviews the areas that Dryden Flight Research Center has set up for testing small Unmanned Aerial Systems (UAS). It also reviews the requirements and process to use an area for UAS test.

  8. San Joaquin Valley Aerosol Health Effects Research Center (SAHERC)

    Data.gov (United States)

    Federal Laboratory Consortium — At the San Joaquin Valley Aerosol Health Effects Center, located at the University of California-Davis, researchers will investigate the properties of particles that...

  9. Center for Urban Environmental Research and Education (CUERE)

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Urban Environmental Research and Education (CUERE) at UMBC was created in 2001 with initial support from the U.S. Environmental Protection Agency and...

  10. Translational Partnership Development Lead | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Frederick National Laboratory for Cancer Research (FNLCR) is a Federally Funded Research and Development Center operated by Leidos Biomedical Research, Inc on behalf of the National Cancer Institute (NCI). The staff of FNLCR support the NCI’s mission in the fight against cancer and HIV/AIDS. Currently we are seeking a Translational Partnership

  11. The Creation and Role of the USDA Biomass Research Centers

    Science.gov (United States)

    William F. Anderson; Jeffery Steiner; Randy Raper; Ken Vogel; Terry Coffelt; Brenton Sharratt; Bob Rummer; Robert L. Deal; Alan Rudie

    2011-01-01

    The Five USDA Biomass Research Centers were created to facilitate coordinated research to enhance the establishment of a sustainable feedstock production for bio-based renewable energy in the United States. Scientists and staff of the Agricultural Research Service (ARS) and Forest Service (FS) within USDA collaborate with other federal agencies, universities and...

  12. Karlsruhe Nuclear Research Center. Research and development program 1992

    International Nuclear Information System (INIS)

    1991-01-01

    The KfK R and D activities are classified by ten point-of-main-effort projects: 1) low-pollution/low-waste methods, 2) environmental energy and mass transfers, 3) nuclear fusion, 4) nuclear saftey research, 5) radioactive waste management, 6) superconduction, 7) microtechnics, 8) materials handling, 9) materials and interfaces, 10) basic physical research. (orig.) [de

  13. Current research in Radiation Biology and Biochemistry Division

    International Nuclear Information System (INIS)

    Tarachand, U.; Singh, B.B.

    1995-01-01

    The Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay has been engaged in research in the frontier areas of (i) radiation biology related to tumour therapy and injury caused by free radicals; (ii) molecular basis of diseases of physiological origin; (iii) molecular aspects of chemical carcinogenesis and (iv) structure of genome and genome related functions. The gist of research and development activities carried out in the Division during the last two years are documented

  14. Current research in Radiation Biology and Biochemistry Division

    Energy Technology Data Exchange (ETDEWEB)

    Tarachand, U; Singh, B B [eds.; Bhabha Atomic Research Centre, Bombay (India). Radiation Biology and Biochemistry Div.

    1996-12-31

    The Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay has been engaged in research in the frontier areas of (i) radiation biology related to tumour therapy and injury caused by free radicals; (ii) molecular basis of diseases of physiological origin; (iii) molecular aspects of chemical carcinogenesis and (iv) structure of genome and genome related functions. The gist of research and development activities carried out in the Division during the last two years are documented.

  15. Karlsruhe Nuclear Research Center. Research and development programme 1988

    International Nuclear Information System (INIS)

    1987-01-01

    A general survey of planned activities and developmental trends of the nuclear research centre is followed by a more detailed account of projects and goals. The various institutes and laboratories are presented together with their specific task schedules. (UA) [de

  16. Karlsruhe Nuclear Research Center. Research and development programme 1989

    International Nuclear Information System (INIS)

    1988-01-01

    The R and D activities of the KfK are classified in 10 main research activities: 1) Project fast breeder; 2) separation nozzle method; 3) project nuclear fusion; 4) project reprocessing and waste processing; 5) ultimate storage; 6) environment and safety; 7) solid-state and materials research; 8) nuclear and elementary particle physics; 9) microtechnics e.g. X-ray lithography; 10) materials handling. (HP) [de

  17. Current research in Canada on biological effects of ionizing radiation

    International Nuclear Information System (INIS)

    Marko, A.M.

    1980-05-01

    A survey of current research in Canada on the biological effects of ionizing radiation has been compiled. The list of projects has been classified according to structure (organizational state of the test system) as well as according to the type of effects. Using several assumptions, ballpark estimates of expenditures on these activities have been made. Agencies funding these research activities have been tabulated and the break-down of research in government laboratories and in academic institutions has been designated. Wherever possible, comparisons have been made outlining differences or similarities that exist between the United States and Canada concerning biological radiation research. It has been concluded that relevant research in this area in Canada is inadequate. Wherever possible, strengths and weaknesses in radiation biology programs have been indicated. The most promising course for Canada to follow is to support adequately fundamental studies of the biological effects of radiation. (auth)

  18. Natural and Accelerated Bioremediation Research (NABIR) Field Research Center (FRC), Oak Ridge Tennessee

    International Nuclear Information System (INIS)

    Watson, David; Jardine, Philip; Gu, Baohua; Parker, Jack; Brandt, Craig; Holladay, Susan; Wolfe, Amy; Bogle, Mary Anna; Lowe, Kenneth; Hyder, Kirk

    2006-01-01

    The Field Research Center (FRC) in Oak Ridge (Fig. 1), Tennessee supports the U.S. Department of Energy's (DOE's) Environmental Remediation Sciences Program (ERSP) goal of understanding the complex physical, chemical, and biological properties of contaminated sites for new solutions to environmental remediation and long-term stewardship. In particular, the FRC provides the opportunity for researchers to conduct studies that promote the understanding of the processes that influence the transport and fate of subsurface contaminants, the effectiveness and long-term consequences of existing remediation options, and the development of improved remediation strategies. It offers a series of contaminated sites around the former S-3 Waste Disposal Ponds and uncontaminated sites in which investigators and students conduct field research or collect samples for laboratory analysis. FRC research also spurs the development of new and improved characterization and monitoring tools. Site specific knowledge gained from research conducted at the FRC also provides the DOE-Oak Ridge Office of Environmental Management (EM) the critical scientific knowledge needed to make cleanup decisions for the S-3 Ponds and other sites on the Oak Ridge Reservation (ORR)

  19. Northwest Hazardous Waste Research, Development, and Demonstration Center: Program Plan

    International Nuclear Information System (INIS)

    1988-02-01

    The Northwest Hazardous Waste Research, Development, and Demonstration Center was created as part of an ongoing federal effort to provide technologies and methods that protect human health and welfare and environment from hazardous wastes. The Center was established by the Superfund Amendments and Reauthorization Act (SARA) to develop and adapt innovative technologies and methods for assessing the impacts of and remediating inactive hazardous and radioactive mixed-waste sites. The Superfund legislation authorized $10 million for Pacific Northwest Laboratory to establish and operate the Center over a 5-year period. Under this legislation, Congress authorized $10 million each to support research, development, and demonstration (RD and D) on hazardous and radioactive mixed-waste problems in Idaho, Montana, Oregon, and Washington, including the Hanford Site. In 1987, the Center initiated its RD and D activities and prepared this Program Plan that presents the framework within which the Center will carry out its mission. Section 1.0 describes the Center, its mission, objectives, organization, and relationship to other programs. Section 2.0 describes the Center's RD and D strategy and contains the RD and D objectives, priorities, and process to be used to select specific projects. Section 3.0 contains the Center's FY 1988 operating plan and describes the specific RD and D projects to be carried out and their budgets and schedules. 9 refs., 18 figs., 5 tabs

  20. Synthesis on biological soil crust research

    Science.gov (United States)

    Weber, Bettina; Belnap, Jayne; Buedel, Burkhard

    2016-01-01

    In this closing chapter, we summarize the advances in biocrust research made during the last 1.5 decades. In the first part of the chapter, we discuss how in some research fields, such as the microbial diversity of fungi, bacteria, and microfauna; the interaction between biocrusts and vascular plants; and in the rehabilitation of biocrusts; particularly large achievements have been made. In other fields, previously established knowledge of overall patterns has been corroborated and refined by additional studies, e.g., in the fields of soil stabilization and disturbance effects. In the second part of the chapter, we outline the research gaps and challenges foreseen by us. We identify multiple knowledge gaps, including many understudied geographic regions, the largely missing link between genetic and morphological species identification data, and the answers to some mechanistic questions, such as the overall role of biocrusts in hydrology and nutrient cycles. With some ideas on promising new research questions and approaches we close this chapter and the overall book.

  1. Contribution to researches in biophysics and biology

    International Nuclear Information System (INIS)

    Luccioni, Catherine

    2000-01-01

    In this accreditation to supervise research, the author indicates its curriculum and scientific works which mainly dealt with the different agents used in chemotherapy. Scientific works addressed anti-carcinogenic pharmacology, applied biophysics, and researches in oncology and radiobiology. Current research projects deal with mechanisms of cellular transformation and the implication of the anti-oxidising metabolism and of nucleotide metabolism in cell radio-sensitivity. Teaching and research supervising activities are also indicated. Several articles are proposed in appendix: Average quality factor and dose equivalent meter based on microdosimetry techniques; Activity of thymidylate synthetase, thymidine kinase and galactokinase in primary and xenografted human colorectal cancers in relation to their chromosomal patterns; Nucleotide metabolism in human gliomas, relation to the chromosomal profile; Pyrimidine nucleotide metabolism in human colon carcinomas: comparison of normal tissues, primary tumors and xenografts; Modifications of the antioxidant metabolism during proliferation and differentiation of colon tumours cell lines; Modulation of the antioxidant enzymes, p21 and p53 expression during proliferation and differentiation of human melanoma cell lines; Purine metabolism in 2 human melanoma cell lines, relation with proliferation and differentiation; Radiation-induced changes in nucleotide metabolism of 2 colon cancer cell lines with different radio-sensitivities

  2. Technologies and experimental approaches in the NIH Botanical Research Centers

    Science.gov (United States)

    Barnes, Stephen; Birt, Diane F; Cassileth, Barrie R; Cefalu, William T; Chilton, Floyd H; Farnsworth, Norman R; Raskin, Ilya; van Breemen, Richard B; Weaver, Connie M

    2009-01-01

    There are many similarities between research on combinatorial chemistry and natural products and research on dietary supplements and botanicals in the NIH Botanical Research Centers. The technologies in the centers are similar to those used by other NIH-sponsored investigators. All centers rigorously examine the authenticity of botanical dietary supplements and determine the composition and concentrations of the phytochemicals therein, most often by liquid chromatography–mass spectrometry. Several of the centers specialize in fractionation and high-throughput evaluation to identify the individual bioactive agent or a combination of agents. Some centers are using DNA microarray analyses to determine the effects of botanicals on gene transcription with the goal of uncovering the important biochemical pathways they regulate. Other centers focus on bioavailability and uptake, distribution, metabolism, and excretion of the phytochemicals as for all xenobiotics. Because phytochemicals are often complex molecules, synthesis of isotopically labeled forms is carried out by plant cells in culture, followed by careful fractionation. These labeled phytochemicals allow the use of accelerator mass spectrometry to trace the tissue distribution of 14C-labeled proanthocyanidins in animal models of disease. State-of-the-art proteomics and mass spectrometry are also used to identify proteins in selected tissues whose expression and posttranslational modification are influenced by botanicals and dietary supplements. In summary, the skills needed to carry out botanical centers’ research are extensive and may exceed those practiced by most NIH investigators. PMID:18258642

  3. Pursuing Personal Passion: Learner-Centered Research Mentoring.

    Science.gov (United States)

    Phillips, William R

    2018-01-01

    New researchers often face difficulty finding and focusing research questions. I describe a new tool for research mentoring, the Pursuing Personal Passion (P3) interview, and a systematic approach to help learners organize their curiosity and develop researchable questions aligned with their personal and professional priorities. The learner-centered P3 research interview parallels the patient-centered clinical interview. This paper reviews experience with 27 research mentees over the years 2009 to 2016, using the P3 approach to identify their initial research topics, classify their underlying passions and track the evolution into their final research questions. These researchers usually identified one of three personal passions that provided lenses to focus their research: problem, person, or process. Initial research topics focused on: problem (24%, 6), person (48%, 12) and process (28%, 7). Final research questions evolved into: problem (20%, 5), person (32%, 8) and process (48%, 12). Identification of the underlying passion can lead researchers who start with one general topic to develop it into very different research questions. Using this P3 approach, mentors can help new researchers focus their interests into researchable questions, successful studies, and organized programs of scholarship.

  4. International Research and Development in Systems Biology

    Science.gov (United States)

    2005-10-01

    Genetics Berlin, Germany Hans Lehrach, Edda Klipp, Silke Sperling Yeast stress response and mitochondrial damage; Downs syndrome; cardiac...molgen.mpg.de, Dr. Edda Klipp, Axel Kowald, Christoph Wierling, Dr. Silke Sperling BACKGROUND The Max Planck Institute for Molecular Genetics was...the cardiovascular genetics group. RESEARCH PROJECTS Dr. Edda Klipp is the head of the kinetic modeling group. She described her group’s

  5. The Center for Regenerative Biology and Medicine at Mount Desert Island Biological Laboratory

    Science.gov (United States)

    2013-06-01

    Polypterus samples respectively. Employing similar biostatistical parameters, we identified 33-shared miRNAs that are highly downregulated during...Wheaton College, Dr. Kenneth Poss from Duke Medical Center and Dr. Jorge Contreras from University of New Jersey School of Medicine and Dentistry

  6. NASA Space Engineering Research Center for VLSI systems design

    Science.gov (United States)

    1991-01-01

    This annual review reports the center's activities and findings on very large scale integration (VLSI) systems design for 1990, including project status, financial support, publications, the NASA Space Engineering Research Center (SERC) Symposium on VLSI Design, research results, and outreach programs. Processor chips completed or under development are listed. Research results summarized include a design technique to harden complementary metal oxide semiconductors (CMOS) memory circuits against single event upset (SEU); improved circuit design procedures; and advances in computer aided design (CAD), communications, computer architectures, and reliability design. Also described is a high school teacher program that exposes teachers to the fundamentals of digital logic design.

  7. Moving from Damage-Centered Research through Unsettling Reflexivity

    Science.gov (United States)

    Calderon, Dolores

    2016-01-01

    The author revisits autoethnographic work in order to examine how she unwittingly incorporated damage-centered (Tuck 2009) research approaches that reproduce settler colonial understandings of marginalized communities. The paper examines the reproduction of settler colonial knowledge in ethnographic research by unearthing the inherent surveillance…

  8. Bibliography of Lewis Research Center Technical Publications announced in 1991

    Science.gov (United States)

    1992-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific engineering work performed and managed by the Lewis Research Center in 1991. All the publications were announced in the 1991 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  9. Stable isotopes: essential tools in biological and medical research

    Energy Technology Data Exchange (ETDEWEB)

    Klein, P. D.; Hachey, D. L.; Kreek, M. J.; Schoeller, D. A.

    1977-01-01

    Recent developments in the use of the stable isotopes, /sup 13/C, /sup 15/N, /sup 17/O, and /sup 18/O, as tracers in research studies in the fields of biology, medicine, pharmacology, and agriculture are briefly reviewed. (CH)

  10. Social justice and research using human biological material: A ...

    African Journals Online (AJOL)

    Social justice and research using human biological material: A response to Mahomed, Nöthling-Slabbert and Pepper. ... South African Medical Journal ... In a recent article, Mahomed, Nöthling-Slabbert and Pepper proposed that research participants should be entitled to share in the profits emanating from such research ...

  11. Biological Research in Canisters (BRIC) - Light Emitting Diode (LED)

    Science.gov (United States)

    Levine, Howard G.; Caron, Allison

    2016-01-01

    The Biological Research in Canisters - LED (BRIC-LED) is a biological research system that is being designed to complement the capabilities of the existing BRIC-Petri Dish Fixation Unit (PDFU) for the Space Life and Physical Sciences (SLPS) Program. A diverse range of organisms can be supported, including plant seedlings, callus cultures, Caenorhabditis elegans, microbes, and others. In the event of a launch scrub, the entire assembly can be replaced with an identical back-up unit containing freshly loaded specimens.

  12. Spacecraft Fire Safety Research at NASA Glenn Research Center

    Science.gov (United States)

    Meyer, Marit

    2016-01-01

    Appropriate design of fire detection systems requires knowledge of both the expected fire signature and the background aerosol levels. Terrestrial fire detection systems have been developed based on extensive study of terrestrial fires. Unfortunately there is no corresponding data set for spacecraft fires and consequently the fire detectors in current spacecraft were developed based upon terrestrial designs. In low gravity, buoyant flow is negligible which causes particles to concentrate at the smoke source, increasing their residence time, and increasing the transport time to smoke detectors. Microgravity fires have significantly different structure than those in 1-g which can change the formation history of the smoke particles. Finally the materials used in spacecraft are different from typical terrestrial environments where smoke properties have been evaluated. It is critically important to detect a fire in its early phase before a flame is established, given the fixed volume of air on any spacecraft. Consequently, the primary target for spacecraft fire detection is pyrolysis products rather than soot. Experimental investigations have been performed at three different NASA facilities which characterize smoke aerosols from overheating common spacecraft materials. The earliest effort consists of aerosol measurements in low gravity, called the Smoke Aerosol Measurement Experiment (SAME), and subsequent ground-based testing of SAME smoke in 55-gallon drums with an aerosol reference instrument. Another set of experiments were performed at NASAs Johnson Space Center White Sands Test Facility (WSTF), with additional fuels and an alternate smoke production method. Measurements of these smoke products include mass and number concentration, and a thermal precipitator was designed for this investigation to capture particles for microscopic analysis. The final experiments presented are from NASAs Gases and Aerosols from Smoldering Polymers (GASP) Laboratory, with selected

  13. The role of architectural research centers in addressing climate change

    Directory of Open Access Journals (Sweden)

    John Carmody

    2012-10-01

    Full Text Available ABSTRACT: It is clear that an urgent, major transformation needs to happen in the design of the built environment to respond to impending climate change and other environmental degradation. This paper will explain the potential role of architectural research centers in this transformation and provide examples from the Center for Sustainable Building Research (CSBR at the University of Minnesota. A research center can become a regional hub to coordinate and disseminate critical information. CSBR is leading the establishment of Architecture 2030 standards in Minnesota, assisting local governments in writing green building policy, providing design assistance to local government, developing tools to assist design decision making, providing technical assistance to the affordable housing community inMinnesota, and establishing a regional case study database that includes actual performance information. CSBR is creating a publicly accessible, credible knowledge base on new approaches, technologies and actual performance outcomes. Research centers such as CSBR can be a critical component of the necessary feedback loop often lacking in the building industry. A research center can also fill major gaps in providing in depth professional education as well as be a catalyst for demonstration projects and public education.

  14. Qualitative Methods in Patient-Centered Outcomes Research.

    Science.gov (United States)

    Vandermause, Roxanne; Barg, Frances K; Esmail, Laura; Edmundson, Lauren; Girard, Samantha; Perfetti, A Ross

    2017-02-01

    The Patient-Centered Outcomes Research Institute (PCORI), created to fund research guided by patients, caregivers, and the broader health care community, offers a new research venue. Many (41 of 50) first funded projects involved qualitative research methods. This study was completed to examine the current state of the science of qualitative methodologies used in PCORI-funded research. Principal investigators participated in phenomenological interviews to learn (a) how do researchers using qualitative methods experience seeking funding for, implementing and disseminating their work; and (b) how may qualitative methods advance the quality and relevance of evidence for patients? Results showed the experience of doing qualitative research in the current research climate as "Being a bona fide qualitative researcher: Staying true to research aims while negotiating challenges," with overlapping patterns: (a) researching the elemental, (b) expecting surprise, and (c) pushing boundaries. The nature of qualitative work today was explicitly described and is rendered in this article.

  15. Establishing a national research center on day care

    DEFF Research Database (Denmark)

    Ellegaard, Tomas

    The paper presents and discusses the current formation of a national research center on ECEC. The center is currently being established. It is partly funded by the Danish union of early childhood and youth educators. It is based on cooperation between a number of Danish universities and this nati...... current new public management policies. However there is also more conflicting issues that emerge in this enterprise – especially on interests, practice relevance and knowledge paradigms....

  16. CUBED: South Dakota 2010 Research Center For Dusel Experiments

    International Nuclear Information System (INIS)

    Keller, Christina; Alton, Drew; Bai Xinhau; Durben, Dan; Heise, Jaret; Hong Haiping; Howard, Stan; Jiang Chaoyang; Keeter, Kara; McTaggart, Robert; Medlin, Dana; Mei Dongming; Petukhov, Andre; Rauber, Joel; Roggenthen, Bill; Spaans, Jason; Sun Yongchen; Szczerbinska, Barbara; Thomas, Keenan; Zehfus, Michael

    2010-01-01

    With the selection of the Homestake Mine in western South Dakota by the National Science Foundation (NSF) as the site for a national Deep Underground Science and Engineering Laboratory (DUSEL), the state of South Dakota has sought ways to engage its faculty and students in activities planned for DUSEL. One such effort is the creation of a 2010 Research Center focused on ultra-low background experiments or a Center for Ultra-low Background Experiments at DUSEL (CUBED). The goals of this center include to 1) bring together the current South Dakota faculty so that one may begin to develop a critical mass of expertise necessary for South Dakota's full participation in large-scale collaborations planned for DUSEL; 2) to increase the number of research faculty and other research personnel in South Dakota to complement and supplement existing expertise in nuclear physics and materials sciences; 3) to be competitive in pursuit of external funding through the creation of a center which focuses on areas of interest to experiments planned for DUSEL such as an underground crystal growth lab, a low background counting facility, a purification/depletion facility for noble liquids, and an electroforming copper facility underground; and 4) to train and educate graduate and undergraduate students as a way to develop the scientific workforce of the state. We will provide an update on the activities of the center and describe in more detail the scientific foci of the center.

  17. The Systems Biology Research Tool: evolvable open-source software

    Directory of Open Access Journals (Sweden)

    Wright Jeremiah

    2008-06-01

    Full Text Available Abstract Background Research in the field of systems biology requires software for a variety of purposes. Software must be used to store, retrieve, analyze, and sometimes even to collect the data obtained from system-level (often high-throughput experiments. Software must also be used to implement mathematical models and algorithms required for simulation and theoretical predictions on the system-level. Results We introduce a free, easy-to-use, open-source, integrated software platform called the Systems Biology Research Tool (SBRT to facilitate the computational aspects of systems biology. The SBRT currently performs 35 methods for analyzing stoichiometric networks and 16 methods from fields such as graph theory, geometry, algebra, and combinatorics. New computational techniques can be added to the SBRT via process plug-ins, providing a high degree of evolvability and a unifying framework for software development in systems biology. Conclusion The Systems Biology Research Tool represents a technological advance for systems biology. This software can be used to make sophisticated computational techniques accessible to everyone (including those with no programming ability, to facilitate cooperation among researchers, and to expedite progress in the field of systems biology.

  18. 76 FR 37085 - Applications for New Awards; Rehabilitation Engineering Research Centers (RERCs)

    Science.gov (United States)

    2011-06-24

    ... DEPARTMENT OF EDUCATION Applications for New Awards; Rehabilitation Engineering Research Centers...)--Disability and Rehabilitation Research Projects and Centers Program--Rehabilitation Engineering Research... (Rehabilitation Act). Rehabilitation Engineering Research Centers Program (RERCs) The purpose of the RERC program...

  19. La Gestión de Investigación del Centro de Inmunología y productos biológicos en el contexto universitario. Un caso de estudio Research management at the Center of Immunology and Biological Products within the university context. A case study

    Directory of Open Access Journals (Sweden)

    Imilla Casado Hernández

    2009-08-01

    results on the quality of life, especially in Latin America. This paper deals with the assessment of research relations at the Center of Immunology and Biological Products within the context of the Medical University of Camagüey. We carried out a retrospective descriptive study, using the methods of theoretical and empiric knowledge. The characterization of the center’s research process showed unconnected and dependent working style, and an unfavorable work environment. In addition, the center failed to be among the strengths of the Vice-Rector’s Office of Investigations. In a general sense, the Medical University of Camagüey showed a reductionistic scientific culture and little social commitment caused by a lack of vision as well as of knowledge of the specific activities of science and technique. As research management has been considered an essential element for establishing general contexts to integrate research processes with the most inclusive purposes of higher educational centers, we recommend designing a strategy to involve the center in the university’s research activity.

  20. Analysis of radiological risks in biological research centers english

    International Nuclear Information System (INIS)

    Usera, F.; Hidalgo, R.M.; Macias, M.T.

    1998-01-01

    The work identifies the amount by which pollution and irradiation risks affect the staff. This was done in order to prevent them and also to establish the most adequate means and methodology for their reduction. For that, we have given priority to determine whether the staff applies in a correct way specific protection means available. And also, if they know the risks to which they are exposed taking into account methods they employ

  1. An Information Building on Radioactivity and Nuclear Energy for the French CEA Cadarache Research Center - 13492

    Energy Technology Data Exchange (ETDEWEB)

    Brunel, Guy; Denis, Dominique; Boulet, Alain [Commissariat a l' energie Atomique et aux Energies Alternatives - CEA-Cadarache, DEN/CEACAD/UCAP, 13108 Saint Paul lez Durance Cedex (France)

    2013-07-01

    The CEA Cadarache research center is one of the 10 research centers of the French Alternative Energies and Atomic Energy Commission (CEA). Distributed throughout various research platforms, it focuses on nuclear fission, nuclear fusion, new energy technologies (hydrogen, solar, biomass) and fundamental research in the field of vegetal biology. It is the most important technological research and development centers for energy in Europe. Considering the sensitive nature of nuclear activities, the questions surrounding the issue of radioactive waste, the nuclear energy and the social, economic and environmental concerns for present and future generations, the French Government asked nuclear actors to open communication and to give all the information asked by the Local Information Commission (CLI) and the public [1]. In this context, the CEA Cadarache has decided to better show and explain its expertise and experience in the area of nuclear energy and nuclear power plant design, and to make it available to stakeholders and to the public. CEA Cadarache receives each year more than 9000 visitors. To complete technical visits of the research facilities and laboratories, a scientific cultural center has been built in 2011 to inform the public on CEA Cadarache research activities and to facilitate the acceptance of nuclear energy in a way suited to the level of knowledge of the visitors. A modern interactive exhibition of 150 m{sup 2} allows visitors to find out more about energy, CEA Cadarache research programs, radioactive waste management and radiological impact on the research center activities. It also offers an auditorium for group discussions and for school groups to discover science through enjoyment. This communication center has received several thousand visitors since its opening on October 2011; the initial results of this experience are now available. It's possible to explain the design of this exhibition, to give some statistics on the number of the

  2. An Information Building on Radioactivity and Nuclear Energy for the French CEA Cadarache Research Center - 13492

    International Nuclear Information System (INIS)

    Brunel, Guy; Denis, Dominique; Boulet, Alain

    2013-01-01

    The CEA Cadarache research center is one of the 10 research centers of the French Alternative Energies and Atomic Energy Commission (CEA). Distributed throughout various research platforms, it focuses on nuclear fission, nuclear fusion, new energy technologies (hydrogen, solar, biomass) and fundamental research in the field of vegetal biology. It is the most important technological research and development centers for energy in Europe. Considering the sensitive nature of nuclear activities, the questions surrounding the issue of radioactive waste, the nuclear energy and the social, economic and environmental concerns for present and future generations, the French Government asked nuclear actors to open communication and to give all the information asked by the Local Information Commission (CLI) and the public [1]. In this context, the CEA Cadarache has decided to better show and explain its expertise and experience in the area of nuclear energy and nuclear power plant design, and to make it available to stakeholders and to the public. CEA Cadarache receives each year more than 9000 visitors. To complete technical visits of the research facilities and laboratories, a scientific cultural center has been built in 2011 to inform the public on CEA Cadarache research activities and to facilitate the acceptance of nuclear energy in a way suited to the level of knowledge of the visitors. A modern interactive exhibition of 150 m 2 allows visitors to find out more about energy, CEA Cadarache research programs, radioactive waste management and radiological impact on the research center activities. It also offers an auditorium for group discussions and for school groups to discover science through enjoyment. This communication center has received several thousand visitors since its opening on October 2011; the initial results of this experience are now available. It's possible to explain the design of this exhibition, to give some statistics on the number of the visitors

  3. The experimental teaching reform in biochemistry and molecular biology for undergraduate students in Peking University Health Science Center.

    Science.gov (United States)

    Yang, Xiaohan; Sun, Luyang; Zhao, Ying; Yi, Xia; Zhu, Bin; Wang, Pu; Lin, Hong; Ni, Juhua

    2015-01-01

    Since 2010, second-year undergraduate students of an eight-year training program leading to a Doctor of Medicine degree or Doctor of Philosophy degree in Peking University Health Science Center (PKUHSC) have been required to enter the "Innovative talent training project." During that time, the students joined a research lab and participated in some original research work. There is a critical educational need to prepare these students for the increasing accessibility of research experience. The redesigned experimental curriculum of biochemistry and molecular biology was developed to fulfill such a requirement, which keeps two original biochemistry experiments (Gel filtration and Enzyme kinetics) and adds a new two-experiment component called "Analysis of anti-tumor drug induced apoptosis." The additional component, also known as the "project-oriented experiment" or the "comprehensive experiment," consists of Western blotting and a DNA laddering assay to assess the effects of etoposide (VP16) on the apoptosis signaling pathways. This reformed laboratory teaching system aims to enhance the participating students overall understanding of important biological research techniques and the instrumentation involved, and to foster a better understanding of the research process all within a classroom setting. Student feedback indicated that the updated curriculum helped them improve their operational and self-learning capability, and helped to increase their understanding of theoretical knowledge and actual research processes, which laid the groundwork for their future research work. © 2015 The International Union of Biochemistry and Molecular Biology.

  4. Fort Collins Science Center- Policy Analysis and Science Assistance Branch : Integrating social, behavioral, economic and biological sciences

    Science.gov (United States)

    2010-01-01

    The Fort Collins Science Center's Policy Analysis and Science Assistance (PASA) Branch is a team of approximately 22 scientists, technicians, and graduate student researchers. PASA provides unique capabilities in the U.S. Geological Survey by leading projects that integrate social, behavioral, economic, and biological analyses in the context of human-natural resource interactions. Resource planners, managers, and policymakers in the U.S. Departments of the Interior (DOI) and Agriculture (USDA), State and local agencies, as well as international agencies use information from PASA studies to make informed natural resource management and policy decisions. PASA scientists' primary functions are to conduct both theoretical and applied social science research, provide technical assistance, and offer training to advance performance in policy relevant research areas. Management and research issues associated with human-resource interactions typically occur in a unique context, involve difficult to access populations, require knowledge of both natural/biological science in addition to social science, and require the skill to integrate multiple science disciplines. In response to these difficult contexts, PASA researchers apply traditional and state-of-the-art social science methods drawing from the fields of sociology, demography, economics, political science, communications, social-psychology, and applied industrial organization psychology. Social science methods work in concert with our rangeland/agricultural management, wildlife, ecology, and biology capabilities. The goal of PASA's research is to enhance natural resource management, agency functions, policies, and decision-making. Our research is organized into four broad areas of study.

  5. Energy Frontier Research Centers: Impact Report, January 2017

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-01-31

    Since its inception in 2009, the U. S. Department of Energy’s Energy Frontier Research Center (EFRC) program has become an important research modality in the Department’s portfolio, enabling high impact research that addresses key scientific challenges for energy technologies. Funded by the Office of Science’s Basic Energy Sciences program, the EFRCs are located across the United States and are led by universities, national laboratories, and private research institutions. These multi-investigator, multidisciplinary centers bring together world-class teams of researchers, often from multiple institutions, to tackle the toughest scientific challenges preventing advances in energy technologies. The EFRCs’ fundamental scientific advances are having a significant impact that is being translated to industry. In 2009 five-year awards were made to 46 EFRCs, including 16 that were fully funded by the American Recovery and Reinvestment Act (ARRA). An open recompetition of the program in 2014 resulted in fouryear awards to 32 centers, 22 of which are renewals of existing EFRCs and 10 of which are new EFRCs. In 2016, DOE added four new centers to accelerate the scientific breakthroughs needed to support the Department’s environmental management and nuclear cleanup mission, bringing the total number of active EFRCs to 36. The impact reports in this document describe some of the many scientific accomplishments and greater impacts of the class of 2009 – 2018 EFRCs and early outcomes from a few of the class of 2014 – 2018 EFRCs.

  6. Coastal Research Center Woods Hole Oceanographic Institution Report for the Period March 1986-July 1988

    Science.gov (United States)

    1989-03-01

    providing instrumentation, supplies, ship time and travel that are essential before a thesis project can be formulated. In the past we have successfully...Between Hytperiid Amphi- pods and salps Dean M. Jacobson Department/Advisor: Department of Biology/D. Anderson Degree/Date: Ph.D./February 1987...Research Center often provides partial support in the form of travel , publication or organizational expenses for symposia and workshops in Woods Hole or

  7. A practical workflow for making anatomical atlases for biological research.

    Science.gov (United States)

    Wan, Yong; Lewis, A Kelsey; Colasanto, Mary; van Langeveld, Mark; Kardon, Gabrielle; Hansen, Charles

    2012-01-01

    The anatomical atlas has been at the intersection of science and art for centuries. These atlases are essential to biological research, but high-quality atlases are often scarce. Recent advances in imaging technology have made high-quality 3D atlases possible. However, until now there has been a lack of practical workflows using standard tools to generate atlases from images of biological samples. With certain adaptations, CG artists' workflow and tools, traditionally used in the film industry, are practical for building high-quality biological atlases. Researchers have developed a workflow for generating a 3D anatomical atlas using accessible artists' tools. They used this workflow to build a mouse limb atlas for studying the musculoskeletal system's development. This research aims to raise the awareness of using artists' tools in scientific research and promote interdisciplinary collaborations between artists and scientists. This video (http://youtu.be/g61C-nia9ms) demonstrates a workflow for creating an anatomical atlas.

  8. Quarterly report of Biological and Medical Research Division, April 1955

    Energy Technology Data Exchange (ETDEWEB)

    Brues, A.M.

    1955-04-01

    This report is a compilation of 48 investigator prepared summaries of recent progress in individual research programs of the Biology and Medical Division of the Argonne National Laboratory for the quarterly period ending April,1955. Individual reports are about 3-6 pages in length and often contain research data.

  9. Twenty-fifth anniversary of the Juelich Nuclear Research Center

    International Nuclear Information System (INIS)

    Haefele, W.

    1982-01-01

    On December 10, 1981, KFA Juelich celebrated its 25th year of existence; on December 11, 1956, the land parliament of North Rhine Westphalia had decided in favour of the erection of a joint nuclear research facility of the land of North Rhine Westphalia. In contrast to other nuclear research centers, the Juelich centre was to develop and operate large-scale research equipment and infrastructure for joint use by the universities of the land. This cooperation has remained an important characteristic in spite of the independent scientific work of KFA institutes, Federal government majorities, and changes in research fields and tasks. KFA does fundamental research in nuclear and plasma physics, solid state research, medicine, life sciences, and environmental research; other activities are R + D tasks for the HTR reactor and its specific applications as well as energy research in general. (orig.) [de

  10. Center for modeling of turbulence and transition: Research briefs, 1995

    Science.gov (United States)

    1995-10-01

    This research brief contains the progress reports of the research staff of the Center for Modeling of Turbulence and Transition (CMOTT) from July 1993 to July 1995. It also constitutes a progress report to the Institute of Computational Mechanics in Propulsion located at the Ohio Aerospace Institute and the Lewis Research Center. CMOTT has been in existence for about four years. In the first three years, its main activities were to develop and validate turbulence and combustion models for propulsion systems, in an effort to remove the deficiencies of existing models. Three workshops on computational turbulence modeling were held at LeRC (1991, 1993, 1994). At present, CMOTT is integrating the CMOTT developed/improved models into CFD tools which can be used by the propulsion systems community. This activity has resulted in an increased collaboration with the Lewis CFD researchers.

  11. List of scientific publications, Nuclear Research Center Karlsruhe 1984

    International Nuclear Information System (INIS)

    1985-04-01

    The report abstracted contains a list of works published in 1984. Papers not in print yet are listed separately. Patent entries take account of all patent rights granted or published in 1984, i.e. patents or patent specifications. The list of publications is classified by institutes. The project category lists but the respective reports and studies carried out and published by members of the project staff concerned. Also listed are publications related to research and development projects of the 'product engineering project' (PFT/Projekt 'Fertigungstechnik'). With different companies and institutes cooperating, PFT is sponsored by Nuclear Research Center Karlsruhe GmbH. The latter is also responsible for printing above publications. Moreover the list contains the publications of a branch of the Bundesforschungsanstalt fuer Ernaehrung which is located on the KfK-premises. The final chapter of the list summarizes publications dealing with guest-experiments and research at Nuclear Research Center Karlsruhe. (orig./PW) [de

  12. A Program of Research and Education in Astronautics at the NASA Langley Research Center

    Science.gov (United States)

    Tolson, Robert H.

    2000-01-01

    The objectives of the Program were to conduct research at the NASA Langley Research Center in the area of astronautics and to provide a comprehensive education program at the Center leading to advanced degrees in Astronautics. We believe that the program has successfully met the objectives and has been of significant benefit to NASA LaRC, the GWU and the nation.

  13. Massachusetts Institute of Technology, Plasma Fusion Center, Technical Research Programs

    International Nuclear Information System (INIS)

    1980-08-01

    A review is given of the technical programs carried out by the Plasma Fusion Center. The major divisions of work areas are applied plasma research, confinement experiments, fusion technology and engineering, and fusion systems. Some objectives and results of each program are described

  14. Scholarly Citadel in Chicago: The Center for Research Libraries.

    Science.gov (United States)

    Boylan, Ray

    1979-01-01

    The Center provides access to infrequently used research materials in three interrelated ways: (1) it provides a deposit library for such materials from the collections of member libraries; (2) it acquires such materials at members' shared expense and for their common use; and (3) it provides rapid access to its collection materials. (Author/JD)

  15. Re:Centering Adult Education Research: Whose World Is First?

    Science.gov (United States)

    Hall, Budd L.

    1993-01-01

    The discourse of adult education research needs to be reframed to place at the center the issues and concerns of the majority of the world's people who live in poverty, ill health, and insecurity and at the margins the concerns of the rich and powerful. (SK)

  16. Massachusetts Institute of Technology, Plasma Fusion Center, Technical Research Programs

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, Ronald C.

    1980-08-01

    A review is given of the technical programs carried out by the Plasma Fusion Center. The major divisions of work areas are applied plasma research, confinement experiments, fusion technology and engineering, and fusion systems. Some objectives and results of each program are described. (MOW)

  17. ADVANCED COMPOSITES TECHNOLOGY CASE STUDY AT NASA LANGLEY RESEARCH CENTER

    Science.gov (United States)

    This report summarizes work conducted at the National Aeronautics and Space Administration's Langley Research Center (NASA-LaRC) in Hampton, VA, under the U.S. Environmental Protection Agency’s (EPA) Waste Reduction Evaluations at Federal Sites (WREAFS) Program. Support for...

  18. The Amistad Research Center: Documenting the African American Experience.

    Science.gov (United States)

    Chepesiuk, Ron

    1993-01-01

    Describes the Amistad Research Center housed at Tulane University which is a repository of primary documents on African-American history. Topics addressed include the development and growth of the collection; inclusion of the American Missionary Association archives; sources of support; civil rights; and collecting for the future. (LRW)

  19. Does Every Research Library Need a Digital Humanities Center?

    Science.gov (United States)

    Schaffner, Jennifer; Erway, Ricky

    2014-01-01

    The digital humanities (DH) are attracting considerable attention and funding at the same time that this nascent field is striving for an identity. Some research libraries are making significant investments by creating digital humanities centers. However, questions about whether such investments are warranted persist across the cultural heritage…

  20. Bituminization of radioactive wastes at the Nuclear Research Center Karlsruhe

    International Nuclear Information System (INIS)

    Hild, W.; Kluger, W.; Krause, H.

    1976-05-01

    A summary is given of the main operational experience gained at the Nuclear Research Center Karlsruhe in 4 years operation of the bituminization plant for evaporator concentrates from low- and medium level wastes. At the same time some of the essential results are compiled that have been obtained in the R + D activities on bituminization. (orig.) [de

  1. Research Centers & Consortia | College of Engineering & Applied Science

    Science.gov (United States)

    Academics Admission Student Life Research Schools & Colleges Libraries Athletics Centers & ; Applied Science Powerful Ideas. Proven Results. Search for: Go This site All UWM Search Site Menu Skip to content Academics Undergraduate Programs Majors Minors Integrated Bachelor/Master Degree Applied Computing

  2. Scientific and technical information output of the Langley Research Center

    Science.gov (United States)

    1984-01-01

    Scientific and technical information that the Langley Research Center produced during the calendar year 1983 is compiled. Included are citations for Formal Reports, Quick-Release Technical Memorandums, Contractor Reports, Journal Articles and other Publications, Meeting Presentations, Technical Talks, Computer Programs, Tech Briefs, and Patents.

  3. Nuclear research center looks for 4000 pressure-cookers

    International Nuclear Information System (INIS)

    Anon.

    2013-01-01

    The CEA/Valduc research center has recently made a strange bid for the purchase of 4000 stainless steel pressure-cookers. In fact pressure-cookers are economical containers perfectly fitted for keeping radioactive materials. About 10.000 pressure-cookers have been bought in the last 50 years by CEA/Valduc. (A.C.)

  4. Meharry-Johns Hopkins Center for Prostate Cancer Research

    Science.gov (United States)

    2015-11-01

    formerly at the Institute for Health, Social, and Community Research (IHSCR) Center for Survey Research ( CSR ) at Shaw University in Raleigh, NC...survey will be conducted at CSR which is now located at Johns Hopkins Bloomberg School of Public Health (JHBSPH) located in Raleigh, NC. The Sons...the strategy to contact sons for whom she had no address or phone number. It was hoped that the father will notify the son to contact the study

  5. The materials processing research base of the Materials Processing Center

    Science.gov (United States)

    Latanision, R. M.

    1986-01-01

    An annual report of the research activities of the Materials Processing Center of the Massachusetts Institute of Technology is given. Research on dielectrophoresis in the microgravity environment, phase separation kinetics in immiscible liquids, transport properties of droplet clusters in gravity-free fields, probes and monitors for the study of solidification of molten semiconductors, fluid mechanics and mass transfer in melt crystal growth, and heat flow control and segregation in directional solidification are discussed.

  6. Bibliography of Lewis Research Center technical publications announced in 1990

    Science.gov (United States)

    1991-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1990. All the publications were announced in the 1990 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  7. Bibliography of Lewis Research Center technical publications announced in 1992

    Science.gov (United States)

    1993-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1992. All the publications were announced in the 1992 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  8. Bibliography of Lewis Research Center technical publications announced in 1993

    Science.gov (United States)

    1994-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1993. All the publications were announced in the 1993 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  9. Bibliography of Lewis Research Center technical publications announced in 1989

    Science.gov (United States)

    1990-01-01

    This compilation of abstracts describes and indexes the technical reporting that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1989. All the publications were announced in the 1989 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Included are research reports, journal articles, conference presentations, patents and patent applications, and theses.

  10. Implementing multidisciplinary research center infrastructure - A trendsetting example: SUNUM

    OpenAIRE

    Birkan, Burak; Özgüz, Volkan Hüsnü; Ozguz, Volkan Husnu

    2014-01-01

    Sabanci University Nanotechnology Research and Application Center (SUNUM) became operational in January 2012. SUNUM is a trendsetting example of a green and flexible research facility that is a test bed for the cost-effective operation of a Centralized Demand-Controlled Ventilation (CDCV) system, a state-of-the-art cleanroom, and world-class high technology equipment. The total investment in the facility was US$35 million.

  11. Bringing the physical sciences into your cell biology research.

    Science.gov (United States)

    Robinson, Douglas N; Iglesias, Pablo A

    2012-11-01

    Historically, much of biology was studied by physicists and mathematicians. With the advent of modern molecular biology, a wave of researchers became trained in a new scientific discipline filled with the language of genes, mutants, and the central dogma. These new molecular approaches have provided volumes of information on biomolecules and molecular pathways from the cellular to the organismal level. The challenge now is to determine how this seemingly endless list of components works together to promote the healthy function of complex living systems. This effort requires an interdisciplinary approach by investigators from both the biological and the physical sciences.

  12. A preliminary exploration of Advanced Molecular Bio-Sciences Research Center

    International Nuclear Information System (INIS)

    Yamada, Yutaka; Yanai, Takanori; Onodera, Jun'ichi; Yamagami, Mutsumi; Sakata, Hiroshi; Sota, Masahiro; Takemura, Tatsuo; Koyama, Kenji; Sato, Fumiaki

    2000-01-01

    Low-dose and low-dose-rate radiation effects on life-span, pathological changes, hemopoiesis and cytokine production in experimental animals have been investigated in our laboratory. In the intermediate period of the investigation, an expert committee on radiation biology, which was composed of two task groups, was organized. The purposes of the committee were to assess of previous studies and plan future research for Advanced Molecular Bio-Sciences Research Center (AMBIC). In its report, the committee emphasized the necessity of molecular research in radiation biology and ecology, and proposed six subjects for the research: 1) Molecular carcinogenesis of low-dose radiation; 2) Radiation effects on the immune system and hemopoietic system; 3) Molecular mechanisms of hereditary effect; 4) Non cancer effect of low-dose radiation; 5) Gene targeting for ion transport system in plants; 6) Bioremediation with transgenic plant and bacteria. Exploration of the AMBIC project will continue under the committee's direction. (author)

  13. Biological and Physical Space Research Laboratory 2002 Science Review

    Science.gov (United States)

    Curreri, P. A. (Editor); Robinson, M. B. (Editor); Murphy, K. L. (Editor)

    2003-01-01

    With the International Space Station Program approaching core complete, our NASA Headquarters sponsor, the new Code U Enterprise, Biological and Physical Research, is shifting its research emphasis from purely fundamental microgravity and biological sciences to strategic research aimed at enabling human missions beyond Earth orbit. Although we anticipate supporting microgravity research on the ISS for some time to come, our laboratory has been vigorously engaged in developing these new strategic research areas.This Technical Memorandum documents the internal science research at our laboratory as presented in a review to Dr. Ann Whitaker, MSFC Science Director, in July 2002. These presentations have been revised and updated as appropriate for this report. It provides a snapshot of the internal science capability of our laboratory as an aid to other NASA organizations and the external scientific community.

  14. [Tissue repositories for research at Sheba Medical Center(SMC].

    Science.gov (United States)

    Cohen, Yehudit; Barshack, Iris; Onn, Amir

    2013-06-01

    Cancer is the number one cause of death in both genders. Breakthroughs in the understanding of cancer biology, the identification of prognostic factors, and the development of new treatments are increasingly dependent on access to human cancer tissues with linked clinicopathological data. Access to human tumor samples and a large investment in translational research are needed to advance this research. The SMC tissue repositories provide researchers with biological materials, which are essential tools for cancer research. SMC tissue repositories for research aim to collect, document and preserve human biospecimens from patients with cancerous diseases. This is in order to provide the highest quality and well annotated biological biospecimens, used as essential tools to achieve the growing demands of scientific research needs. Such repositories are partners in acceLerating biomedical research and medical product development through clinical resources, in order to apply best options to the patients. Following Institutional Review Board approval and signing an Informed Consent Form, the tumor and tumor-free specimens are coLLected by a designated pathologist at the operating room only when there is a sufficient amount of the tumor, in excess of the routine needs. Blood samples are collected prior to the procedure. Other types of specimens collected include ascites fluid, pleural effusion, tissues for Optimal Cutting Temperature [OCT] and primary culture etc. Demographic, clinical, pathologicaL, and follow-up data are collected in a designated database. SMC has already established several organ or disease-specific tissue repositories within different departments. The foundation of tissue repositories requires the concentrated effort of a multidisciplinary team composed of paramedical, medical and scientific professionals. Research projects using these specimens facilitate the development of 'targeted therapy', accelerate basic research aimed at clarifying molecular

  15. NASA Space Biology Plant Research for 2010-2020

    Science.gov (United States)

    Levine, H. G.; Tomko, D. L.; Porterfield, D. M.

    2012-01-01

    The U.S. National Research Council (NRC) recently published "Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era" (http://www.nap.edu/catalog.php?record id=13048), and NASA completed a Space Biology Science Plan to develop a strategy for implementing its recommendations ( http://www.nasa.gov/exploration/library/esmd documents.html). The most important recommendations of the NRC report on plant biology in space were that NASA should: (1) investigate the roles of microbial-plant systems in long-term bioregenerative life support systems, and (2) establish a robust spaceflight program of research analyzing plant growth and physiological responses to the multiple stimuli encountered in spaceflight environments. These efforts should take advantage of recently emerged analytical technologies (genomics, transcriptomics, proteomics, metabolomics) and apply modern cellular and molecular approaches in the development of a vigorous flight-based and ground-based research program. This talk will describe NASA's strategy and plans for implementing these NRC Plant Space Biology recommendations. New research capabilities for Plant Biology, optimized by providing state-of-the-art automated technology and analytical techniques to maximize scientific return, will be described. Flight experiments will use the most appropriate platform to achieve science results (e.g., ISS, free flyers, sub-orbital flights) and NASA will work closely with its international partners and other U.S. agencies to achieve its objectives. One of NASA's highest priorities in Space Biology is the development research capabilities for use on the International Space Station and other flight platforms for studying multiple generations of large plants. NASA will issue recurring NASA Research Announcements (NRAs) that include a rapid turn-around model to more fully engage the biology community in designing experiments to respond to the NRC recommendations. In doing so, NASA

  16. Alpha waste management at the Valduc Research Center

    International Nuclear Information System (INIS)

    Jouan, A.; Cartier, R.; Durec, J.P.; Flament, T.

    1995-01-01

    Operation of the reprocessing facilities at the Valduc Research Center of the French Atomic Energy Commission (CEA) generates waste with a variety of characteristics. The waste compatible with surface storage requirements is transferred to the French Radioactive Waste Management Agency (ANDRA); rest is reprocessed under a program which enables storage in compliance with the requirements of permits issued by safety Authorities. The waste reprocessing program provides for the construction of an incinerator capable of handling nearly all of the combustible waste generated by the Center and vitrification facility for treating liquid waste generated by the plutonium handling plant. (authors)

  17. Waste management at the Karlsruhe Nuclear Research Center

    International Nuclear Information System (INIS)

    Hoehlein, G.; Lins, W.

    1982-01-01

    In the Karlsruhe Nuclear Research Center the responsibility for waste management is concentrated in the Decontamination Department which serves to collect and transport all liquid waste and solid material from central areas in the center for further waste treatment, clean radioactive equipment for repair and re-use or for recycling of material, remove from the liquid effluents any radioactive and chemical pollutants as specified in legislation on the protection of waters, convert radioactive wastes into mechanically and chemically stable forms allowing them to be transported into a repository. (orig./RW)

  18. Applied wind energy research at the National Wind Technology Center

    International Nuclear Information System (INIS)

    Robinson, M.C.; Tu, P.

    1997-01-01

    Applied research activities currently being undertaken at the National Wind Technology Center, part of the National Renewable Energy Laboratory, in the United States, are divided into several technical disciplines. An integrated multi-disciplinary approach is urged for the future in order to evaluate advanced turbine designs. The risk associated with any new turbine development program can thus be mitigated through the provision of the advanced technology, analysis tools and innovative designs available at the Center, and wind power can be promoted as a viable renewable energy alternative. (UK)

  19. SWOT analysis in Sina Trauma and Surgery Research Center.

    Science.gov (United States)

    Salamati, Payman; ashraf Eghbali, Ali; Zarghampour, Manijeh

    2014-01-01

    The present study was conducted with the aim of identifying and evaluating the internal and external factors, affecting the Sina Trauma and Surgery Research Center, affiliated to Tehran University of Medical Sciences and propose some of related strategies to senior managers. We used a combined quantitative and qualitative methodology. Our study population consisted of personnel (18 individuals) at Sina Trauma and Surgery Research Center. Data-collection tools were the group discussions and the questionnaires. Data were analyzed with descriptive statistics and SWOT (Strength, Weakness, Opportunities and Threats) analysis. 18 individuals participated in sessions, consisting of 8 women (44.4%) and 10 men (55.6%). The final scores were 2.45 for internal factors (strength-weakness) and 2.17 for external factors (opportunities-threats). In this study, we proposed 36 strategies (10 weakness-threat strategies, 10 weakness-opportunity strategies, 7 strength-threat strategies, and 9 strength-opportunity strategies). The current status of Sina Trauma and Surgery Research Center is threatened weak. We recommend the center to implement the proposed strategies.

  20. Nuclear Research Center Karlsruhe, Central Safety Department. Annual report 1992

    International Nuclear Information System (INIS)

    Koelzer, W.

    1993-05-01

    The Central Safety Department is responsible for handling all problems of radiation protection, safety and security of the institutes and departments of the Karlsruhe Nuclear Research Center, for waste water activity measurements and environmental monitoring of the whole area of the Center, and for research and development work mainly focusing on nuclear safety and radiation protection measures. The research and development work concentrates on the following aspects: Physical and chemical behavior of trace elements in the environment, biophysics of multicellular systems, behavior of tritium in the air/soil-plant system, improvement in radiation protection measurement and personnel dosimetry. This report gives details of the different duties, indicates the results of 1992 routine tasks and reports about results of investigations and developments of the working groups of the Department. The reader is referred to the English translation of Chapter 1 describing the duties and organization of the Central Safety Department. (orig.) [de

  1. Project 'European Research Center for Air Pollution Abatement Measures'

    International Nuclear Information System (INIS)

    1985-04-01

    During the 5-7th of March 1985 the first status report of the project 'European Research Center for Air Pollution Control Measures' took place in the Nuclear Research Center, Karlsruhe. Progress reports on the following topics assessment and analysis of the impacts of airborne pollutants on forest trees; distinction from other potential causes of recent forest dieback, research into atmospheric dispersion, conversion and deposition of airborne pollutants, development and optimization of industrial-technical processes to reduce or avoid emissions and providing instruments and making recommendations to the industrial and political sectors were presented. This volume is a collection of the work reported there. 42 papers were entered separately. (orig./MG) [de

  2. Karlsruhe Nuclear Research Center, Central Safety Department. Annual report 1993

    International Nuclear Information System (INIS)

    Koelzer, W.

    1994-04-01

    The Central Safety Department is responsible for handling all tasks of radiation protection, safety and security of the institutes and departments of the Karlsruhe Nuclear Research Center, for waste water activity measurements and environmental monitoring of the whole area of the Center, and for research and development work mainly focusing on nuclear safety and radiation protection measures. The research and development work concentrates on the following aspects: behavior of trace elements in the environment and decontamination of soil, behavior of tritium in the air/soil-plant system, improvement in radiation protection measurements and personnel dosimetry. This report gives details of the different duties, indicates the results of 1993 routine tasks and reports about results of investigations and developments of the working groups of the Department. (orig.) [de

  3. Double Star Research: A Student-Centered Community of Practice

    Science.gov (United States)

    Johnson, Jolyon

    2016-06-01

    Project and team-based pedagogies are increasingly augmenting lecture-style science classrooms. Occasionally, university professors will invite students to tangentially partcipate in their research. Since 2006, Dr. Russ Genet has led an astronomy research seminar for community college and high school students that allows participants to work closely with a melange of professional and advanced amatuer researchers. The vast majority of topics have centered on measuring the position angles and searations of double stars which can be readily published in the Journal of Double Star Observations. In the intervening years, a collaborative community of practice (Wenger, 1998) formed with the students as lead researchers on their projects with the guidance of experienced astronomers and educators. The students who join the research seminar are often well prepared for further STEM education in college and career. Today, the research seminar involves multile schools in multiple states with a volunteer educator acting as an assistant instructor at each location. These assistant instructors interface with remote observatories, ensure progress is made, and recruit students. The key deliverables from each student team include a published research paper and a public presentation online or in-person. Citing a published paper on scholarship and college applications gives students' educational carreers a boost. Recently the Journal of Double Star Observations published its first special issue of exlusively student-centered research.

  4. Decommissioning Operations at the Cadarache Nuclear Research Center

    International Nuclear Information System (INIS)

    Gouhier, E.

    2008-01-01

    Among the different activities of the CEA research center of Cadarache, located in the south of France, one of the most important involves decommissioning. As old facilities close, decommissioning activity increases. This presentation will give an overview of the existing organization and the different ongoing decommissioning and cleanup operations on the site. We shall also present some of the new facilities under construction the purpose of which is to replace the decommissioned ones. Cadarache research center was created on October 14, 1959. Today, the activities of the research center are shared out among several technological R and D platforms, essentially devoted to nuclear energy (fission and fusion) Acting as a support to these R and D activities, the center of Cadarache has a platform of services which groups the auxiliary services required by the nuclear facilities and those necessary to the management of nuclear materials, waste, nuclear facility releases and decommissioning. Many old facilities have shut down in recent years (replaced by new facilities) and a whole decommissioning program is now underway involving the dismantling of nuclear reactors (Rapsodie, Harmonie), processing facilities (ATUE uranium treatment facility, LECA UO 2 facility) as well as waste treatment and storage facilities (INB37, INB 56. In conclusion: other dismantling and cleanup operations that are now underway in Cadarache include the following: - Waste treatment and storage facilities, - Historical VLLW and HLW storage facility, - Fissile material storage building, - Historical spent fuel storage facility. Thanks to the project organization: - Costs and risks on these projects can be reduced. - Engineers and technicians can easily move from one project to another. In some cases, when a new facility is under construction for the purpose of replacing a decommissioned one, some of the project team can integrate the new facility as members of the operation team. Today

  5. Large space antenna communications systems: Integrated Langley Research Center/Jet Propulsion Laboratory development activities. 2: Langley Research Center activities

    Science.gov (United States)

    Cambell, T. G.; Bailey, M. C.; Cockrell, C. R.; Beck, F. B.

    1983-01-01

    The electromagnetic analysis activities at the Langley Research Center are resulting in efficient and accurate analytical methods for predicting both far- and near-field radiation characteristics of large offset multiple-beam multiple-aperture mesh reflector antennas. The utilization of aperture integration augmented with Geometrical Theory of Diffraction in analyzing the large reflector antenna system is emphasized.

  6. Evaluation of a fungal collection as certified reference material producer and as a biological resource center

    Directory of Open Access Journals (Sweden)

    Tatiana Forti

    2016-06-01

    Full Text Available Abstract Considering the absence of standards for culture collections and more specifically for biological resource centers in the world, in addition to the absence of certified biological material in Brazil, this study aimed to evaluate a Fungal Collection from Fiocruz, as a producer of certified reference material and as Biological Resource Center (BRC. For this evaluation, a checklist based on the requirements of ABNT ISO GUIA34:2012 correlated with the ABNT NBR ISO/IEC17025:2005, was designed and applied. Complementing the implementation of the checklist, an internal audit was performed. An evaluation of this Collection as a BRC was also conducted following the requirements of the NIT-DICLA-061, the Brazilian internal standard from Inmetro, based on ABNT NBR ISO/IEC 17025:2005, ABNT ISO GUIA 34:2012 and OECD Best Practice Guidelines for BRCs. This was the first time that the NIT DICLA-061 was applied in a culture collection during an internal audit. The assessments enabled the proposal for the adequacy of this Collection to assure the implementation of the management system for their future accreditation by Inmetro as a certified reference material producer as well as its future accreditation as a Biological Resource Center according to the NIT-DICLA-061.

  7. Evaluation of a fungal collection as certified reference material producer and as a biological resource center.

    Science.gov (United States)

    Forti, Tatiana; Souto, Aline da S S; do Nascimento, Carlos Roberto S; Nishikawa, Marilia M; Hubner, Marise T W; Sabagh, Fernanda P; Temporal, Rosane Maria; Rodrigues, Janaína M; da Silva, Manuela

    2016-01-01

    Considering the absence of standards for culture collections and more specifically for biological resource centers in the world, in addition to the absence of certified biological material in Brazil, this study aimed to evaluate a Fungal Collection from Fiocruz, as a producer of certified reference material and as Biological Resource Center (BRC). For this evaluation, a checklist based on the requirements of ABNT ISO GUIA34:2012 correlated with the ABNT NBR ISO/IEC17025:2005, was designed and applied. Complementing the implementation of the checklist, an internal audit was performed. An evaluation of this Collection as a BRC was also conducted following the requirements of the NIT-DICLA-061, the Brazilian internal standard from Inmetro, based on ABNT NBR ISO/IEC 17025:2005, ABNT ISO GUIA 34:2012 and OECD Best Practice Guidelines for BRCs. This was the first time that the NIT DICLA-061 was applied in a culture collection during an internal audit. The assessments enabled the proposal for the adequacy of this Collection to assure the implementation of the management system for their future accreditation by Inmetro as a certified reference material producer as well as its future accreditation as a Biological Resource Center according to the NIT-DICLA-061. Copyright © 2016 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

  8. Activities in biological radiation research at the AGF

    International Nuclear Information System (INIS)

    1984-01-01

    The AGF is working on a wide spectrum of biological radiation research, with the different scientific disciplines contributing different methodologies to long-term research projects. The following fields are studied: 1. Molecular and cellular modes of action of radiation. 2. Detection and characterisation of biological radiation damage, especially in humans. 3. Medical applications of radiation effects. 4. Concepts and methods of radiation protection. The studies will lead to suggestions for radiation protection and improved radiotherapy. They may also contribute to the development of environmental protection strategies. (orig./MG) [de

  9. The value of closed-circuit rebreathers for biological research

    Science.gov (United States)

    Pyle, Richrad L.; Lobel, Phillip S.; Tomoleoni, Joseph

    2016-01-01

    Closed-circuit rebreathers have been used for underwater biological research since the late 1960s, but have only started to gain broader application within scientific diving organizations within the past two decades. Rebreathers offer certain specific advantages for such research, especially for research involving behavior and surveys that depend on unobtrusive observers or for a stealthy approach to wildlife for capture and tagging, research that benefits from extended durations underwater, and operations requiring access to relatively deep (>50 m) environments (especially in remote locations). Although many institutions have been slow to adopt rebreather technology within their diving programs, recent developments in rebreather technology that improve safety, standardize training requirements, and reduce costs of equipment and maintenance, will likely result in a trend of increasing utilization of rebreathers for underwater biological research.

  10. Patient-centered prioritization of bladder cancer research.

    Science.gov (United States)

    Smith, Angela B; Chisolm, Stephanie; Deal, Allison; Spangler, Alejandra; Quale, Diane Z; Bangs, Rick; Jones, J Michael; Gore, John L

    2018-05-04

    Patient-centered research requires the meaningful involvement of patients and caregivers throughout the research process. The objective of this study was to create a process for sustainable engagement for research prioritization within oncology. From December 2014 to 2016, a network of engaged patients for research prioritization was created in partnership with the Bladder Cancer Advocacy Network (BCAN): the BCAN Patient Survey Network (PSN). The PSN leveraged an online bladder cancer community with additional recruitment through print advertisements and social media campaigns. Prioritized research questions were developed through a modified Delphi process and were iterated through multidisciplinary working groups and a repeat survey. In year 1 of the PSN, 354 patients and caregivers responded to the research prioritization survey; the number of responses increased to 1034 in year 2. The majority of respondents had non-muscle-invasive bladder cancer (NMIBC), and the mean time since diagnosis was 5 years. Stakeholder-identified questions for noninvasive, invasive, and metastatic disease were prioritized by the PSN. Free-text questions were sorted with thematic mapping. Several questions submitted by respondents were among the prioritized research questions. A final prioritized list of research questions was disseminated to various funding agencies, and a highly ranked NMIBC research question was included as a priority area in the 2017 Patient-Centered Outcomes Research Institute announcement of pragmatic trial funding. Patient engagement is needed to identify high-priority research questions in oncology. The BCAN PSN provides a successful example of an engagement infrastructure for annual research prioritization in bladder cancer. The creation of an engagement network sets the groundwork for additional phases of engagement, including design, conduct, and dissemination. Cancer 2018. © 2018 American Cancer Society. © 2018 American Cancer Society.

  11. A preliminary exploration of the advanced molecular bio-sciences research center

    International Nuclear Information System (INIS)

    Yanai, Takanori; Yamada, Yutaka; Tanaka, Kimio; Yamagami, Mutsumi; Sota, Masahiro; Takemura, Tatsuo; Koyama, Kenji; Sato, Fumiaki

    2001-01-01

    Low dose and low dose rate radiation effects on lifespan, pathological changes, hemopoiesis and cytokine production in mice have been investigated in our laboratory. In the intermediate period of the investigation, an expert committee on radiation biology was organized. The purposes of the committee were to assess previous studies and advise on a future research plan for the Advanced Molecular Bio-Sciences Research Center (AMBIC). The committee emphasized the necessity of molecular research in radiation biology, and proposed the following five subjects: 1) molecular carcinogenesis by low dose radiation; 2) radiation effects on the immune and hemopoietic systems; 3) molecular mechanisms of hereditary effect; 4) noncancer diseases of low dose radiation, and 5) cellular mechanisms by low dose radiation. (author)

  12. Public relations activities of the Karlsruhe Nuclear Research Center - a national research center contributes to opinion forming

    International Nuclear Information System (INIS)

    Koerting, K.

    1988-01-01

    At the Karlsruhe Nuclear Research Center, the Public Relations Department directly reports to the Chief Executive Officer. The head of the Public Relation Department acts as spokesman of the center in the public, which requires him to be fully informed of the work of all units and of the policy goals of the executive board. The key tools used by the Public Relations Department are KfK-Hausmitteilungen, accident information, the scientific journal KfK-Nachrichten, press releases, exhibitions, fairs, guided tours, and nuclear energy information staff. (DG)

  13. New York can be our nation's center for Alzheimer's research.

    Science.gov (United States)

    Vann, Allan S

    2014-09-01

    More than 5 million people in this country have Alzheimer's disease, and more than 300,000 of those with Alzheimer's live in New York. By 2025, it is estimated that there will be 350,000 residents living with Alzheimer's in New York. Congressman Steve Israel and New York Assemblyman Charles Lavine issued a joint proposal in June, 2013 suggesting that New York become this country's center for Alzheimer's research. Obviously, they would both like to see increased federal funding, but they also know that we cannot count on that happening. So Israel and Lavine have proposed a $3 billion state bonding initiative to secure sufficient funding to tackle this disease. It would be similar to the bonding initiatives that have made California and Texas this nation's centers for stem cell and cancer research. The bond would provide a dedicated funding stream to support research to find effective means to treat, cure, and eventually prevent Alzheimer's, and fund programs to help people currently dealing with Alzheimer's and their caregivers. New York already has some of the major "ingredients" to make an Alzheimer's bond initiative a success, including 3 of our nation's 29 Alzheimer's Disease Research Centers and some of the finest research facilities in the nation for genetic and neuroscience research. One can only imagine the synergy of having these world class institutions working on cooperative grants and projects with sufficient funding to attract even more world class researchers and scientists to New York to find ways to prevent, treat, and cure Alzheimer's. © The Author(s) 2014.

  14. Bibliographical review on the teaching of Biology and research

    Directory of Open Access Journals (Sweden)

    Mª Luz Rodríguez Palmero

    2000-09-01

    Full Text Available This review complements another one done by the same author, in 1997, regarding the role of comprehending the concept of cell in the learning of Biology. In addition, some general papers on science education that provide a better understanding of research approaches used in the investigation of this topic have been included. The reviewed papers have been organized into categories according to the object of study, the relevance assigned to the cell concept, and the framework of analysis. The review shows that the concept of cell is very important in the biological conceptualization, however, it also shows the need of additional research on this matter, from theoretical frameworks that pay more attention to the psychological level, in order to provide some guidance to improve the teaching and learning processes of the biological content that presupose the comprehension of living beings.

  15. 34 CFR 350.34 - Which Rehabilitation Engineering Research Centers must have an advisory committee?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Which Rehabilitation Engineering Research Centers must... Engineering Research Centers Does the Secretary Assist? § 350.34 Which Rehabilitation Engineering Research Centers must have an advisory committee? A Rehabilitation Engineering Research Center conducting research...

  16. Using curriculum vitae to compare some impacts of NSF research grants with research center funding

    OpenAIRE

    Monica Gaughan; Barry Bozeman

    2002-01-01

    While traditional grants remain central in US federal support of academic scientists and engineers, the role of multidisciplinary NSF Centers is growing. Little is known about how funding through these Centers affects scientific output or (as is an NSF aim) increases academic collaboration with industry. This paper tests the use of CVs to examine how Center funding affects researchers' publication rates and their obtaining industry grants. Copyright , Beech Tree Publishing.

  17. Tennessee Valley Authority National Fertilizer and Environmental Research Center

    International Nuclear Information System (INIS)

    Gautney, J.

    1991-01-01

    The National Fertilizer and Environmental Research Center (NFERC) is a unique part of the Tennessee Valley Authority (TVA), a government agency created by an Act of Congress in 1933. The Center, located in Muscle Shoals, Alabama, is a national laboratory for research, development, education and commercialization for fertilizers and related agricultural chemicals including their economic and environmentally safe use, renewable fuel and chemical technologies, alternatives for solving environmental/waste problems, and technologies which support national defense- NFERC projects in the pesticide waste minimization/treatment/disposal areas include ''Model Site Demonstrations and Site Assessments,'' ''Development of Waste Treatment and Site Remediation Technologies for Fertilizer/Agrichemical Dealers,'' ''Development of a Dealer Information/Education Program,'' and ''Constructed Wetlands.''

  18. The NIH-NIAID Filariasis Research Reagent Resource Center.

    Directory of Open Access Journals (Sweden)

    Michelle L Michalski

    2011-11-01

    Full Text Available Filarial worms cause a variety of tropical diseases in humans; however, they are difficult to study because they have complex life cycles that require arthropod intermediate hosts and mammalian definitive hosts. Research efforts in industrialized countries are further complicated by the fact that some filarial nematodes that cause disease in humans are restricted in host specificity to humans alone. This potentially makes the commitment to research difficult, expensive, and restrictive. Over 40 years ago, the United States National Institutes of Health-National Institute of Allergy and Infectious Diseases (NIH-NIAID established a resource from which investigators could obtain various filarial parasite species and life cycle stages without having to expend the effort and funds necessary to maintain the entire life cycles in their own laboratories. This centralized resource (The Filariasis Research Reagent Resource Center, or FR3 translated into cost savings to both NIH-NIAID and to principal investigators by freeing up personnel costs on grants and allowing investigators to divert more funds to targeted research goals. Many investigators, especially those new to the field of tropical medicine, are unaware of the scope of materials and support provided by the FR3. This review is intended to provide a short history of the contract, brief descriptions of the fiilarial species and molecular resources provided, and an estimate of the impact the resource has had on the research community, and describes some new additions and potential benefits the resource center might have for the ever-changing research interests of investigators.

  19. Lewis Research Center space station electric power system test facilities

    Science.gov (United States)

    Birchenough, Arthur G.; Martin, Donald F.

    1988-01-01

    NASA Lewis Research Center facilities were developed to support testing of the Space Station Electric Power System. The capabilities and plans for these facilities are described. The three facilities which are required in the Phase C/D testing, the Power Systems Facility, the Space Power Facility, and the EPS Simulation Lab, are described in detail. The responsibilities of NASA Lewis and outside groups in conducting tests are also discussed.

  20. Development of laser technology in Research Center of Laser Fusion

    International Nuclear Information System (INIS)

    Zheng Wanguo; Deng Ying; Zhou Wei

    2013-01-01

    This paper reviews the progress in the construction of SG-Ⅲ laser facility, integrated Testbed and XG-Ⅲ laser facility and that in the upgrade of the prototype of SG-Ⅲ, and the development in assembling and installing technology, and the achievements in maintaining cleanliness project and metrology in Laser Fusion Research Center, China Academy of Engineering Physics in China in 2012. (authors)

  1. List of scientific publications of Nuclear Research Center Karlsruhe 1983

    International Nuclear Information System (INIS)

    1984-04-01

    This report contains the titles of the publications edited in the year 1983. The scientific and technical-scientific publications of the Nuclear Research Center Karlsruhe are printed as books, as original contributions in scientific or technical specialists' journals, as scripts for habilitation, thesis, scripts for diploma, as patents, as KfK-Reports (KfK=Kernforschungszentrum Karlsruhe) and are being presented as lectures on scientific meetings. No further separate abstracts of this list of publications were prepared. (orig./HBR) [de

  2. Biomedical Research Experiences for Biology Majors at a Small College

    Science.gov (United States)

    Stover, Shawn K.; Mabry, Michelle L.

    2010-01-01

    A program-level assessment of the biology curriculum at a small liberal arts college validates a previous study demonstrating success in achieving learning outcomes related to content knowledge and communication skills. Furthermore, research opportunities have been provided to complement pedagogical strategies and give students a more complete…

  3. Biologically Enhanced Carbon Sequestration: Research Needs and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Oldenburg, Curtis; Oldenburg, Curtis M.; Torn, Margaret S.

    2008-03-21

    Fossil fuel combustion, deforestation, and biomass burning are the dominant contributors to increasing atmospheric carbon dioxide (CO{sub 2}) concentrations and global warming. Many approaches to mitigating CO{sub 2} emissions are being pursued, and among the most promising are terrestrial and geologic carbon sequestration. Recent advances in ecology and microbial biology offer promising new possibilities for enhancing terrestrial and geologic carbon sequestration. A workshop was held October 29, 2007, at Lawrence Berkeley National Laboratory (LBNL) on Biologically Enhanced Carbon Sequestration (BECS). The workshop participants (approximately 30 scientists from California, Illinois, Oregon, Montana, and New Mexico) developed a prioritized list of research needed to make progress in the development of biological enhancements to improve terrestrial and geologic carbon sequestration. The workshop participants also identified a number of areas of supporting science that are critical to making progress in the fundamental research areas. The purpose of this position paper is to summarize and elaborate upon the findings of the workshop. The paper considers terrestrial and geologic carbon sequestration separately. First, we present a summary in outline form of the research roadmaps for terrestrial and geologic BECS. This outline is elaborated upon in the narrative sections that follow. The narrative sections start with the focused research priorities in each area followed by critical supporting science for biological enhancements as prioritized during the workshop. Finally, Table 1 summarizes the potential significance or 'materiality' of advances in these areas for reducing net greenhouse gas emissions.

  4. Biological field stations: research legacies and sites for serendipity

    Science.gov (United States)

    William K. Michener; Keith L. Bildstein; Arthur McKee; Robert R. Parmenter; William W. Hargrove; Deedra McClearn; Mark Stromberg

    2009-01-01

    Biological field stations are distributed throughout North America, capturing much of the ecological variability present at the continental scale and encompassing many unique habitats. In addition to their role in supporting research and education, field stations offer legacies of data, specimens, and accumulated knowledge. Such legacies often provide the only...

  5. Researchers study decontamination of chemical, biological warfare agents

    OpenAIRE

    Trulove, Susan

    2007-01-01

    The U.S. Army Research Office has awarded Virginia Tech a $680,000 grant over two years to build an instrument that can be used to study the chemistry of gases that will decompose both chemical and biological warfare agents on surfaces.

  6. NASA Space Weather Center Services: Potential for Space Weather Research

    Science.gov (United States)

    Zheng, Yihua; Kuznetsova, Masha; Pulkkinen, Antti; Taktakishvili, A.; Mays, M. L.; Chulaki, A.; Lee, H.; Hesse, M.

    2012-01-01

    The NASA Space Weather Center's primary objective is to provide the latest space weather information and forecasting for NASA's robotic missions and its partners and to bring space weather knowledge to the public. At the same time, the tools and services it possesses can be invaluable for research purposes. Here we show how our archive and real-time modeling of space weather events can aid research in a variety of ways, with different classification criteria. We will list and discuss major CME events, major geomagnetic storms, and major SEP events that occurred during the years 2010 - 2012. Highlights of major tools/resources will be provided.

  7. NASA Glenn Research Center Experience with "LENR Phenomenon"

    Science.gov (United States)

    Wrbanek, Susan Y.; Fralick, Gustave C.; Wrbanek, John D.; Niedra, Janis M.

    2012-01-01

    Since 1989 NASA Glenn Research Center (GRC) has performed some small-scale limited experiments that show evidence of effects claimed by some to be evidence of Low Energy Nuclear Reactions (LENR). The research at GRC has involved observations and work on measurement techniques for observing the temperature effects in reactions of isotopes of hydrogen with palladium hydrides. The various experiments performed involved loading Pd with gaseous H2 and D2, and exposing Pd thin films to multi-bubble sonoluminescence in regular and deuterated water. An overview of these experiments and their results will be presented.

  8. NASA Glenn Research Center Experience with LENR Phenomenon

    Science.gov (United States)

    Wrbanek, Susan Y.; Fralick, Gustave C.; Wrbanek, John D.; Niedra, Janis M.

    2012-01-01

    Since 1989 NASA Glenn Research Center (GRC) has performed some small-scale limited experiments that show evidence of effects claimed by some to be evidence of Low Energy Nuclear Reactions (LENR). The research at GRC has involved observations and work on measurement techniques for observing the temperature effects in reactions of isotopes of hydrogen with palladium hydrides. The various experiments performed involved loading Pd with gaseous H2 and D2, and exposing Pd thin films to multi-bubble sonoluminescence in regular and deuterated water. An overview of these experiments and their results will be presented.

  9. A future perspective on technological obsolescenceat NASA, Langley Research Center

    Science.gov (United States)

    Mcintyre, Robert M.

    1990-01-01

    The present research effort was the first phase of a study to forecast whether technological obsolescence will be a problem for the engineers, scientists, and technicians at NASA Langley Research Center (LaRC). There were four goals of the research: to review the literature on technological obsolescence; to determine through interviews of division chiefs and branch heads Langley's perspective on future technological obsolescence; to begin making contacts with outside industries to find out how they view the possibility of technological obsolescence; and to make preliminary recommendations for dealing with the problem. A complete description of the findings of this research can be reviewed in a technical report in preparation. The following are a small subset of the key findings of the study: NASA's centers and divisions vary in their missions and because of this, in their capability to control obsolescence; research-oriented organizations within NASA are believed by respondents to keep up to date more than the project-oriented organizations; asked what are the signs of a professional's technological obsolescence, respondents had a variety of responses; top performing scientists were viewed as continuous learners, keeping up to date by a variety of means; when asked what incentives were available to aerospace technologists for keeping up to data, respondents specified a number of ideas; respondents identified many obstacles to professionals' keeping up to date in the future; and most respondents expressed some concern for the future of the professionals at NASA vis a vis the issue of professional obsolescence.

  10. Chief, Structural Biophysics Laboratory | Center for Cancer Research

    Science.gov (United States)

    The SBL Chief is expected to establish a strong research program in structural biology/biophysics in addition to providing leadership of the SBL and the structural biology community in the NCI Intramural Program.  Applicants should hold a Ph.D., M.D./Ph.D., or equivalent doctoral degree in a relevant discipline, and should possess outstanding communication skills and documented leadership experience.  Tenured faculty or industrial scientists of equivalent rank with a demonstrated commitment to structural biophysics should apply.  Salary will be commensurate with experience and accomplishments.  This position is not restricted to U.S. citizens. A full civil service package of benefits (including health insurance, life insurance, and retirement) is available. This position is subject to a background investigation.  The NIH is dedicated to building a diverse community in its training and employment programs.

  11. Advancing Cancer Systems Biology: Introducing the Center for the Development of a Virtual Tumor, CViT

    Directory of Open Access Journals (Sweden)

    Sean Martin

    2007-01-01

    Full Text Available Integrative cancer biology research relies on a variety of data-driven computational modeling and simulation methods and techniques geared towards gaining new insights into the complexity of biological processes that are of critical importance for cancer research. These include the dynamics of gene-protein interaction networks, the percolation of subcellular perturbations across scales and the impact they may have on tumorigenesis in both experiments and clinics. Such innovative ‘systems’ research will greatly benefi t from enabling Information Technology that is currently under development, including an online collaborative environment, a Semantic Web based computing platform that hosts data and model repositories as well as high-performance computing access. Here, we present one of the National Cancer Institute’s recently established Integrative Cancer Biology Programs, i.e. the Center for the Development of a Virtual Tumor, CViT, which is charged with building a cancer modeling community, developing the aforementioned enabling technologies and fostering multi-scale cancer modeling and simulation.

  12. Federal Research: Opportunities Exist to Improve the Management and Oversight of Federally Funded Research and Development Centers

    National Research Council Canada - National Science Library

    Woods, William; Mittal, Anu; Neumann, John; Williams, Cheryl; Candon, Sharron; Sterling, Suzanne; Wade, Jacqueline; Zwanzig, Peter

    2008-01-01

    .... FFRDCs -- including laboratories, studies and analyses centers, and systems engineering centers -- conduct research in military space programs, nanotechnology, microelectronics, nuclear warfare...

  13. Current dichotomy between traditional molecular biological and omic research in cancer biology and pharmacology.

    Science.gov (United States)

    Reinhold, William C

    2015-12-10

    There is currently a split within the cancer research community between traditional molecular biological hypothesis-driven and the more recent "omic" forms or research. While the molecular biological approach employs the tried and true single alteration-single response formulations of experimentation, the omic employs broad-based assay or sample collection approaches that generate large volumes of data. How to integrate the benefits of these two approaches in an efficient and productive fashion remains an outstanding issue. Ideally, one would merge the understandability, exactness, simplicity, and testability of the molecular biological approach, with the larger amounts of data, simultaneous consideration of multiple alterations, consideration of genes both of known interest along with the novel, cross-sample comparisons among cell lines and patient samples, and consideration of directed questions while simultaneously gaining exposure to the novel provided by the omic approach. While at the current time integration of the two disciplines remains problematic, attempts to do so are ongoing, and will be necessary for the understanding of the large cell line screens including the Developmental Therapeutics Program's NCI-60, the Broad Institute's Cancer Cell Line Encyclopedia, and the Wellcome Trust Sanger Institute's Cancer Genome Project, as well as the the Cancer Genome Atlas clinical samples project. Going forward there is significant benefit to be had from the integration of the molecular biological and the omic forms or research, with the desired goal being improved translational understanding and application.

  14. pClone: Synthetic Biology Tool Makes Promoter Research Accessible to Beginning Biology Students

    Science.gov (United States)

    Eckdahl, Todd; Cronk, Brian; Andresen, Corinne; Frederick, Paul; Huckuntod, Samantha; Shinneman, Claire; Wacker, Annie; Yuan, Jason

    2014-01-01

    The Vision and Change report recommended genuine research experiences for undergraduate biology students. Authentic research improves science education, increases the number of scientifically literate citizens, and encourages students to pursue research. Synthetic biology is well suited for undergraduate research and is a growing area of science. We developed a laboratory module called pClone that empowers students to use advances in molecular cloning methods to discover new promoters for use by synthetic biologists. Our educational goals are consistent with Vision and Change and emphasize core concepts and competencies. pClone is a family of three plasmids that students use to clone a new transcriptional promoter or mutate a canonical promoter and measure promoter activity in Escherichia coli. We also developed the Registry of Functional Promoters, an open-access database of student promoter research results. Using pre- and posttests, we measured significant learning gains among students using pClone in introductory biology and genetics classes. Student posttest scores were significantly better than scores of students who did not use pClone. pClone is an easy and affordable mechanism for large-enrollment labs to meet the high standards of Vision and Change. PMID:26086659

  15. Actions Needed to Ensure Scientific and Technical Information is Adequately Reviewed at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center

    Science.gov (United States)

    2008-01-01

    This audit was initiated in response to a hotline complaint regarding the review, approval, and release of scientific and technical information (STI) at Johnson Space Center. The complainant alleged that Johnson personnel conducting export control reviews of STI were not fully qualified to conduct those reviews and that the reviews often did not occur until after the STI had been publicly released. NASA guidance requires that STI, defined as the results of basic and applied scientific, technical, and related engineering research and development, undergo certain reviews prior to being released outside of NASA or to audiences that include foreign nationals. The process includes technical, national security, export control, copyright, and trade secret (e.g., proprietary data) reviews. The review process was designed to preclude the inappropriate dissemination of sensitive information while ensuring that NASA complies with a requirement of the National Aeronautics and Space Act of 1958 (the Space Act)1 to provide for the widest practicable and appropriate dissemination of information resulting from NASA research activities. We focused our audit on evaluating the STI review process: specifically, determining whether the roles and responsibilities for the review, approval, and release of STI were adequately defined and documented in NASA and Center-level guidance and whether that guidance was effectively implemented at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center. Johnson was included in the review because it was the source of the initial complaint, and Goddard, Langley, and Marshall were included because those Centers consistently produce significant amounts of STI.

  16. Overview of research in progress at the Center of Excellence

    Science.gov (United States)

    Wandell, Brian A.

    1993-01-01

    The Center of Excellence (COE) was created nine years ago to facilitate active collaboration between the scientists at Ames Research Center and the Stanford Psychology Department. Significant interchange of ideas and personnel continues between Stanford and participating groups at NASA-Ames; the COE serves its function well. This progress report is organized into sections divided by project. Each section contains a list of investigators, a background statement, progress report, and a proposal for work during the coming year. The projects are: Algorithms for development and calibration of visual systems, Visually optimized image compression, Evaluation of advanced piloting displays, Spectral representations of color, Perception of motion in man and machine, Automation and decision making, and Motion information used for navigation and control.

  17. Current NDT activities at Cekmece Nuclear Research and Training Center

    International Nuclear Information System (INIS)

    Ekinci, S.

    2004-01-01

    Nondestructive testing (NDT) activities at Cekmece Nuclear Research and Training Center (CNAEM) has been initiated in the Industrial Application Department of the Center which was established in 1976 as the Radioisotope Applications Group for Industry. The Department started its first NDT activity with industrial radiography. The NDT activities have been developed by the support of various national (State Planning Organization (DPT)) and international (IAEA and UNDP) projects. Today, there are five basic NDT techniques (radiography, ultrasonic, magnetic particle, liquid penetrant and eddy current) used in the Industrial Application Department. The Department arranges routinely NDT qualification courses according to ISO 9712 and TS EN 473 standards for level 1 and 2 for Turkish Industry. It also carries out national DPT and IAEA Technical Co-operation projects and gives NDT services in the laboratory and in the field. Digital radiography and digital ultrasonic techniques are being used in advanced NDT applications. This paper describes the NDT activities of CNAEM. (author)

  18. Invited Review Article: Advanced light microscopy for biological space research

    Science.gov (United States)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; van Loon, Jack J. W. A.; Bereiter-Hahn, Juergen; Stelzer, Ernst H. K.

    2014-10-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  19. Invited Review Article: Advanced light microscopy for biological space research

    International Nuclear Information System (INIS)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; Loon, Jack J. W. A. van; Bereiter-Hahn, Juergen; Stelzer, Ernst H. K.

    2014-01-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy

  20. Invited Review Article: Advanced light microscopy for biological space research

    Energy Technology Data Exchange (ETDEWEB)

    De Vos, Winnok H., E-mail: winnok.devos@uantwerpen.be [Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp (Belgium); Cell Systems and Imaging Research Group, Department of Molecular Biotechnology, Ghent University, Ghent (Belgium); Beghuin, Didier [Lambda-X, Nivelles (Belgium); Schwarz, Christian J. [European Space Agency (ESA), ESTEC, TEC-MMG, Noordwijk (Netherlands); Jones, David B. [Institute for Experimental Orthopaedics and Biomechanics, Philipps University, Marburg (Germany); Loon, Jack J. W. A. van [Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center and Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam, Amsterdam (Netherlands); Bereiter-Hahn, Juergen; Stelzer, Ernst H. K. [Physical Biology, BMLS (FB15, IZN), Goethe University, Frankfurt am Main (Germany)

    2014-10-15

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  1. Energy Frontier Research Center, Center for Materials Science of Nuclear Fuels

    International Nuclear Information System (INIS)

    Allen, Todd R.

    2011-01-01

    The Office of Science, Basic Energy Sciences, has funded the INL as one of the Energy Frontier Research Centers in the area of material science of nuclear fuels. This document is the required annual report to the Office of Science that outlines the accomplishments for the period of May 2010 through April 2011. The aim of the Center for Material Science of Nuclear Fuels (CMSNF) is to establish the foundation for predictive understanding of the effects of irradiation-induced defects on thermal transport in oxide nuclear fuels. The science driver of the center's investigation is to understand how complex defect and microstructures affect phonon mediated thermal transport in UO2, and achieve this understanding for the particular case of irradiation-induced defects and microstructures. The center's research thus includes modeling and measurement of thermal transport in oxide fuels with different levels of impurities, lattice disorder and irradiation-induced microstructure, as well as theoretical and experimental investigation of the evolution of disorder, stoichiometry and microstructure in nuclear fuel under irradiation. With the premise that thermal transport in irradiated UO2 is a phonon-mediated energy transport process in a crystalline material with defects and microstructure, a step-by-step approach will be utilized to understand the effects of types of defects and microstructures on the collective phonon dynamics in irradiated UO2. Our efforts under the thermal transport thrust involved both measurement of diffusive phonon transport (an approach that integrates over the entire phonon spectrum) and spectroscopic measurements of phonon attenuation/lifetime and phonon dispersion. Our distinct experimental efforts dovetail with our modeling effort involving atomistic simulation of phonon transport and prediction of lattice thermal conductivity using the Boltzmann transport framework.

  2. A Community-Building Framework for Collaborative Research Coordination across the Education and Biology Research Disciplines

    Science.gov (United States)

    Pelaez, Nancy; Anderson, Trevor R.; Gardner, Stephanie M.; Yin, Yue; Abraham, Joel K.; Barlett, Edward L.; Gormally, Cara; Hurney, Carol A.; Long, Tammy M.; Newman, Dina L.; Sirum, Karen; Stevens, Michael T.

    2018-01-01

    Since 2009, the U.S. National Science Foundation Directorate for Biological Sciences has funded Research Coordination Networks (RCN) aimed at collaborative efforts to improve participation, learning, and assessment in undergraduate biology education (UBE). RCN-UBE projects focus on coordination and communication among scientists and educators who…

  3. Technical report from Radioactive Waste Management Funding and Research Center

    International Nuclear Information System (INIS)

    2007-10-01

    As the only one Japanese organization specialized in radioactive waste, RWMC (Radioactive Waste Management Funding and Research Center) has been conducting the two major roles; R and D and the fund administration for radioactive waste management. The focus of its studies includes land disposal of LLW (Low-level radioactive wastes) and it has gradually extended to research on management and disposal techniques for high-level (HLW) and TRU wastes and studies on securing and managing the funds required for disposal of these wastes. The present document is the yearly progress report of 2006 and the main activities and research results are included on spent fuel disposal techniques including radon diffusion and emanation problem, performance studies on underground facilities for radioactive waste disposal and its management, technical assessment for geological environment, remote control techniques, artificial barrier systems proposed and its monitoring systems, and TRU disposals. (S. Ohno)

  4. Applied Computational Fluid Dynamics at NASA Ames Research Center

    Science.gov (United States)

    Holst, Terry L.; Kwak, Dochan (Technical Monitor)

    1994-01-01

    The field of Computational Fluid Dynamics (CFD) has advanced to the point where it can now be used for many applications in fluid mechanics research and aerospace vehicle design. A few applications being explored at NASA Ames Research Center will be presented and discussed. The examples presented will range in speed from hypersonic to low speed incompressible flow applications. Most of the results will be from numerical solutions of the Navier-Stokes or Euler equations in three space dimensions for general geometry applications. Computational results will be used to highlight the presentation as appropriate. Advances in computational facilities including those associated with NASA's CAS (Computational Aerosciences) Project of the Federal HPCC (High Performance Computing and Communications) Program will be discussed. Finally, opportunities for future research will be presented and discussed. All material will be taken from non-sensitive, previously-published and widely-disseminated work.

  5. RNA Nanostructures – Methods and Protocols | Center for Cancer Research

    Science.gov (United States)

    RNA nanotechnology is a young field with many potential applications. The goal is to utilize designed RNA strands, such that the obtained constructs have specific properties in terms of shape and functionality. RNA has potential functionalities that are comparable to that of proteins, but possesses (compared to proteins) simpler design principles akin to DNA. The promise is that designed RNA complexes may make possible novel types of molecular assemblies with applications in medicine (as therapeutics or diagnostics), material science, imaging, structural biology, and basic research.

  6. The Austrian Research Centers activities in energy risks

    International Nuclear Information System (INIS)

    Sdouz, Gert

    1998-01-01

    Among the institutions involved in energy analyses in Austria the risk context is being treated by three different entities: the Energy Consumption Agency, internationally known as EVA, the Federal Environmental Protection Agency, or Urnweltbundesarnt assessing mainly the environmental risks involved and the Austrian Research Centers, working on safety and risk evaluation. The Austrian Research Center Seibersdorf draws form its proficiency in Reactor Safety and Fusion Research, two fields of experience it has been involved in since its foundation, for some 40 years now. Nuclear energy is not well accepted by the Austrian population. Therefore in our country only energy systems with advanced safety level might be accepted in the far future. This means that the development of methods to compare risks is an important task. The characteristics of energy systems featuring advanced safety levels are: A very low hazard potential and a focus on deterministic safety instead of probabilistic safety, meaning to rely on inherently safe physics concepts, confirmed by probabilistic safety evaluation results. This can be achieved by adequate design of fusion reactors, advanced fission reactors and all different renewable sources of energy

  7. Final priority; National Institute on Disability and Rehabilitation Research--Disability and Rehabilitation Research Projects and Centers Program--Rehabilitation Engineering Research Centers. Final priority.

    Science.gov (United States)

    2013-06-14

    The Assistant Secretary for Special Education and Rehabilitative Services announces a priority for a Rehabilitation Engineering Research Center (RERC) on Universal Interfaces and Information Technology Access under the Disability and Rehabilitation Research Projects and Centers Program administered by the National Institute on Disability and Rehabilitation Research (NIDRR). The Assistant Secretary may use this priority for a competition in fiscal year (FY) 2013 and later years. We take this action to focus research attention on areas of national need. We intend to use this priority to improve outcomes for individuals with disabilities.

  8. Research Applications of Proteolytic Enzymes in Molecular Biology

    Directory of Open Access Journals (Sweden)

    József Tőzsér

    2013-11-01

    Full Text Available Proteolytic enzymes (also termed peptidases, proteases and proteinases are capable of hydrolyzing peptide bonds in proteins. They can be found in all living organisms, from viruses to animals and humans. Proteolytic enzymes have great medical and pharmaceutical importance due to their key role in biological processes and in the life-cycle of many pathogens. Proteases are extensively applied enzymes in several sectors of industry and biotechnology, furthermore, numerous research applications require their use, including production of Klenow fragments, peptide synthesis, digestion of unwanted proteins during nucleic acid purification, cell culturing and tissue dissociation, preparation of recombinant antibody fragments for research, diagnostics and therapy, exploration of the structure-function relationships by structural studies, removal of affinity tags from fusion proteins in recombinant protein techniques, peptide sequencing and proteolytic digestion of proteins in proteomics. The aim of this paper is to review the molecular biological aspects of proteolytic enzymes and summarize their applications in the life sciences.

  9. Oklahoma State University proposed Advanced Technology Research Center. Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Department of Energy (DOE) has prepared an Environmental Assessment (EA) evaluating the construction and equipping of the proposed Advanced Technology Research Center (ATRC) at Oklahoma State University (OSU) in Stillwater, Oklahoma. Based on the analysis in the EA, the DOE has determined that the proposed action does not constitute a major federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement is not required.

  10. Telecommuting (Work-At-Home) at NASA Lewis Research Center

    Science.gov (United States)

    Srinidhi, Saragur M.

    1994-01-01

    This report presents a study in evaluating the viability of providing a work-at-home (telecommuting) program for Lewis Research Center's corporate employees using Integrated Services Digital Network (ISDN). Case studies have been presented for a range of applications from casual data access to interactive access. The network performance of telemedia applications were studied against future requirements for such level of remote connectivity. Many of the popular ISDN devices were characterized for network and service functionality. A set of recommendations to develop a telecommuting policy have been proposed.

  11. Surface modification and characterization Collaborative Research Center at ORNL

    International Nuclear Information System (INIS)

    1986-01-01

    The Surface Modification and Characterization Collaborative Research Center (SMAC/CRC) is a unique facility for the alteration and characterization of the near-surface properties of materials. The SMAC/CRC facility is equipped with particle accelerators and high-powered lasers which can be used to improve the physical, electrical, and/or chemical properties of solids and to create unique new materials not possible to obtain with conventional ''equilibrium'' processing techniques. Surface modification is achieved using such techniques as ion implantation doping, ion beam mixing, laser mixing, ion deposition, and laser annealing

  12. The Systems Biology Research Tool: evolvable open-source software

    OpenAIRE

    Wright, J; Wagner, A

    2008-01-01

    Abstract Background Research in the field of systems biology requires software for a variety of purposes. Software must be used to store, retrieve, analyze, and sometimes even to collect the data obtained from system-level (often high-throughput) experiments. Software must also be used to implement mathematical models and algorithms required for simulation and theoretical predictions on the system-level. Results We introduce a free, easy-to-use, open-source, integrated software platform calle...

  13. BRIC-60: Biological Research in Canisters (BRIC)-60

    Science.gov (United States)

    Richards, Stephanie E. (Compiler); Levine, Howard G.; Romero, Vergel

    2016-01-01

    The Biological Research in Canisters (BRIC) is an anodized-aluminum cylinder used to provide passive stowage for investigations evaluating the effects of space flight on small organisms. Specimens flown in the BRIC 60 mm petri dish (BRIC-60) hardware include Lycoperscion esculentum (tomato), Arabidopsis thaliana (thale cress), Glycine max (soybean) seedlings, Physarum polycephalum (slime mold) cells, Pothetria dispar (gypsy moth) eggs and Ceratodon purpureus (moss).

  14. Research Applications of Proteolytic Enzymes in Molecular Biology

    OpenAIRE

    Mótyán, János András; Tóth, Ferenc; Tőzsér, József

    2013-01-01

    Proteolytic enzymes (also termed peptidases, proteases and proteinases) are capable of hydrolyzing peptide bonds in proteins. They can be found in all living organisms, from viruses to animals and humans. Proteolytic enzymes have great medical and pharmaceutical importance due to their key role in biological processes and in the life-cycle of many pathogens. Proteases are extensively applied enzymes in several sectors of industry and biotechnology, furthermore, numerous research applications ...

  15. Collaborative Mission Design at NASA Langley Research Center

    Science.gov (United States)

    Gough, Kerry M.; Allen, B. Danette; Amundsen, Ruth M.

    2005-01-01

    NASA Langley Research Center (LaRC) has developed and tested two facilities dedicated to increasing efficiency in key mission design processes, including payload design, mission planning, and implementation plan development, among others. The Integrated Design Center (IDC) is a state-of-the-art concurrent design facility which allows scientists and spaceflight engineers to produce project designs and mission plans in a real-time collaborative environment, using industry-standard physics-based development tools and the latest communication technology. The Mission Simulation Lab (MiSL), a virtual reality (VR) facility focused on payload and project design, permits engineers to quickly translate their design and modeling output into enhanced three-dimensional models and then examine them in a realistic full-scale virtual environment. The authors were responsible for envisioning both facilities and turning those visions into fully operational mission design resources at LaRC with multiple advanced capabilities and applications. In addition, the authors have created a synergistic interface between these two facilities. This combined functionality is the Interactive Design and Simulation Center (IDSC), a meta-facility which offers project teams a powerful array of highly advanced tools, permitting them to rapidly produce project designs while maintaining the integrity of the input from every discipline expert on the project. The concept-to-flight mission support provided by IDSC has shown improved inter- and intra-team communication and a reduction in the resources required for proposal development, requirements definition, and design effort.

  16. Recent progress in structural biology: lessons from our research history.

    Science.gov (United States)

    Nitta, Ryo; Imasaki, Tsuyoshi; Nitta, Eriko

    2018-05-16

    The recent 'resolution revolution' in structural analyses of cryo-electron microscopy (cryo-EM) has drastically changed the research strategy for structural biology. In addition to X-ray crystallography and nuclear magnetic resonance spectroscopy, cryo-EM has achieved the structural analysis of biological molecules at near-atomic resolution, resulting in the Nobel Prize in Chemistry 2017. The effect of this revolution has spread within the biology and medical science fields affecting everything from basic research to pharmaceutical development by visualizing atomic structure. As we have used cryo-EM as well as X-ray crystallography since 2000 to elucidate the molecular mechanisms of the fundamental phenomena in the cell, here we review our research history and summarize our findings. In the first half of the review, we describe the structural mechanisms of microtubule-based motility of molecular motor kinesin by using a joint cryo-EM and X-ray crystallography method. In the latter half, we summarize our structural studies on transcriptional regulation by X-ray crystallography of in vitro reconstitution of a multi-protein complex.

  17. Development and Testing of the Glenn Research Center Visitor's Center Grid-Tied Photovoltaic Power System

    Science.gov (United States)

    Eichenberg, Dennis J.

    2009-01-01

    The NASA Glenn Research Center (GRC) has developed, installed, and tested a 12 kW DC grid-tied photovoltaic (PV) power system at the GRC Visitor s Center. This system utilizes a unique ballast type roof mount for installing the photovoltaic panels on the roof of the Visitor s Center with no alterations or penetrations to the roof. The PV system has generated in excess of 15000 kWh since operation commenced in August 2008. The PV system is providing power to the GRC grid for use by all. Operation of the GRC Visitor s Center PV system has been completely trouble free. A grid-tied PV power system is connected directly to the utility distribution grid. Facility power can be obtained from the utility system as normal. The PV system is synchronized with the utility system to provide power for the facility, and excess power is provided to the utility. The project transfers space technology to terrestrial use via nontraditional partners. GRC personnel glean valuable experience with PV power systems that are directly applicable to various space power systems, and provides valuable space program test data. PV power systems help to reduce harmful emissions and reduce the Nation s dependence on fossil fuels. Power generated by the PV system reduces the GRC utility demand, and the surplus power aids the community. Present global energy concerns reinforce the need for the development of alternative energy systems. Modern PV panels are readily available, reliable, efficient, and economical with a life expectancy of at least 25 years. Modern electronics has been the enabling technology behind grid-tied power systems, making them safe, reliable, efficient, and economical with a life expectancy of at least 25 years. Based upon the success of the GRC Visitor s Center PV system, additional PV power system expansion at GRC is under consideration. The GRC Visitor s Center grid-tied PV power system was successfully designed and developed which served to validate the basic principles

  18. The Role of Computers in Research and Development at Langley Research Center

    Science.gov (United States)

    Wieseman, Carol D. (Compiler)

    1994-01-01

    This document is a compilation of presentations given at a workshop on the role cf computers in research and development at the Langley Research Center. The objectives of the workshop were to inform the Langley Research Center community of the current software systems and software practices in use at Langley. The workshop was organized in 10 sessions: Software Engineering; Software Engineering Standards, methods, and CASE tools; Solutions of Equations; Automatic Differentiation; Mosaic and the World Wide Web; Graphics and Image Processing; System Design Integration; CAE Tools; Languages; and Advanced Topics.

  19. A RESEARCH REPORT ON OPERATIONAL PLANS FOR DEVELOPING REGIONAL EDUCATIONAL MEDIA RESEARCH CENTERS.

    Science.gov (United States)

    CARPENTER, C.R.; AND OTHERS

    THE NEED AND FEASIBILITY OF ESTABLISHING A NUMBER OF "REGIONAL EDUCATIONAL MEDIA RESEARCH CENTERS WITH A PROGRAMMATIC ORIENTATION" WERE INVESTIGATED. A PLANNING GROUP WAS ESTABLISHED TO SERVE AS A STEERING COMMITTEE. CONFERENCES IN WHICH GROUPS IN RESEARCH AND EDUCATION IN WIDELY DISTRIBUTED REGIONS OF THE COUNTRY PARTICIPATED WERE HELD…

  20. Pinon-juniper management research at Corona Range and Livestock Research Center in Central New Mexico

    Science.gov (United States)

    Andres Cibils; Mark Petersen; Shad Cox; Michael Rubio

    2008-01-01

    Description: New Mexico State University's Corona Range and Livestock Research Center (CRLRC) is located in a pinon-juniper (PJ)/grassland ecotone in the southern Basin and Range Province in south central New Mexico. A number of research projects conducted at this facility revolve around soil, plant, livestock, and wildlife responses to PJ woodland management. The...

  1. Biological and chemical technologies research. FY 1995 annual summary report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-03-01

    The annual summary report presents the fiscal year (FY) 1995 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program. This BCTR program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1995 (ASR 95) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization, selected technical and programmatic highlights for 1995; detailed descriptions of individual projects; a listing of program output, including a bibliography of published work; patents; and awards arising from work supported by the BCTR.

  2. 1998 researchers' conference proceedings, Amarillo College Business and Industry Center

    International Nuclear Information System (INIS)

    1998-01-01

    The first Strategic Arms Reduction Treaties (START 1 and 2) signed by the US and the Soviet Union call for a reduction in strategic nuclear warheads to about one-third of 1990 levels and a complete elimination of land-based, multiple-warhead missiles. As a consequence of dismantling nuclear warheads, a significant portion of the inventory of nuclear materials that were formerly parts of deployed weapon systems was designated to be handled and/or stored at the Pantex Plant near Amarillo, Texas. To facilitate research integration between the national laboratories and the universities, the Center has divided its technical activities into seven focus areas. For Nuclear and Other Materials Studies, the focus areas are Materials Science, Plutonium Processing and handling, Nuclear Materials Storage, and analytical Development. The Environment, Safety and Health focus areas are Environmental Restoration and Protection, Safety and Health, and Waste Management. Research projects within each area are presented

  3. PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 66

    International Nuclear Information System (INIS)

    OGAWA, A.

    2005-01-01

    The RIKEN BNL Research Center (RSRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the 'Rikagaku Kenkyusho (RIKEN, The Institute of Physical and Chemical Research) of Japan. The Center is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has both a theory and experimental component. At present the theoretical group has 4 Fellows and 3 Research Associates as well as 11 RHIC Physics/University Fellows (academic year 2003-2004). To date there are approximately 30 graduates from the program of which 13 have attained tenure positions at major institutions worldwide. The experimental group is smaller and has 2 Fellows and 3 RHIC Physics/University Fellows and 3 Research Associates, and historically 6 individuals have attained permanent positions. Beginning in 2001 a new RIKEN Spin Program (RSP) category was implemented at RBRC. These appointments are joint positions of RBRC and RIKEN and include the following positions in theory and experiment: RSP Researchers, RSP Research Associates, and Young Researchers, who are mentored by senior RBRC Scientists, A number of RIKEN Jr. Research Associates and Visiting Scientists also contribute to the physics program at the Center. RBRC has an active workshop program on strong interaction physics with each workshop focused on a specific physics problem. Each workshop speaker is encouraged to select a few of the most important transparencies from his or her presentation, accompanied by a page of explanation. This material is collected at the end of the workshop by the organizer to form proceedings, which can therefore be available within a short time. To date there are sixty nine proceedings volumes available. The construction of a 0.6 teraflops parallel processor, dedicated to lattice QCD, begun at the Center on February 19, 1998, was completed on August 28, 1998 and is still

  4. Two Micron Laser Technology Advancements at NASA Langley Research Center

    Science.gov (United States)

    Singh, Upendra N.

    2010-01-01

    An Independent Laser Review Panel set up to examine NASA s space-based lidar missions and the technology readiness of lasers appropriate for space-based lidars indicated a critical need for an integrated research and development strategy to move laser transmitter technology from low technical readiness levels to the higher levels required for space missions. Based on the review, a multiyear Laser Risk Reduction Program (LRRP) was initiated by NASA in 2002 to develop technologies that ensure the successful development of the broad range of lidar missions envisioned by NASA. This presentation will provide an overview of the development of pulsed 2-micron solid-state laser technologies at NASA Langley Research Center for enabling space-based measurement of wind and carbon dioxide.

  5. Joint development utility and university and utility and research center

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Roberto del Giudice R.; Valgas, Helio Moreira [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil)

    1994-12-31

    This paper shows the background acquired by CEMIG in dealing with projects associated with R and D (Research and Development), carried out as a result of the establishment of contracts or governants with universities and research center for direct application on the solution of problems related to the operation of the system, within the scope of electrical operation planning. The various aspects of a project of this nature such as legal questions, characterization of a contract or a covenant, main developments and new opportunity areas should be covered. Finally the subject shall be dealt with under the Total Quality approach, involving the proposition of control items associated to the process and goals to be reached. (author) 7 refs., 2 figs.

  6. Division of Biological and Medical Research annual technical report, 1981

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1982-06-01

    This report summarizes research during 1981 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Low Level Radiation include comparison of lifetime effects in mice of low level neutron and gamma irradiation, delineation of the responses of dogs to continuous low level gamma irradiation, elucidation of mechanisms of radiation damage and repair in mammalian cells, and study of the genetic effects of high LET radiations. Carcinogenesis research addresses mechanisms of tumor initiation and promotion in rat liver, chemical carcinogenesis in cultured mammalian cells, and molecular and genetic mechanisms of chemical and ultraviolet mutagenesis in bacteria. Research in Toxicology uses a variety of cellular, whole animal, and chronobiological end points, chemical separations, and statistical models to evaluate the hazards and mechanisms of actions of metals, coal gasification by products, and other energy-related pollutants. Human Protein Index studies develop two-dimensional electrophoresis systems for diagnosis and detection of cancer and other disease. Biophysics research includes fundamental structural and biophysical investigations of immunoglobulins and key biological molecules using NMR, crystallographic, and x-ray and neutron small-angle scattering techniques. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies

  7. Division of Biological and Medical Research annual technical report, 1981

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.W. (ed.)

    1982-06-01

    This report summarizes research during 1981 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Low Level Radiation include comparison of lifetime effects in mice of low level neutron and gamma irradiation, delineation of the responses of dogs to continuous low level gamma irradiation, elucidation of mechanisms of radiation damage and repair in mammalian cells, and study of the genetic effects of high LET radiations. Carcinogenesis research addresses mechanisms of tumor initiation and promotion in rat liver, chemical carcinogenesis in cultured mammalian cells, and molecular and genetic mechanisms of chemical and ultraviolet mutagenesis in bacteria. Research in Toxicology uses a variety of cellular, whole animal, and chronobiological end points, chemical separations, and statistical models to evaluate the hazards and mechanisms of actions of metals, coal gasification by products, and other energy-related pollutants. Human Protein Index studies develop two-dimensional electrophoresis systems for diagnosis and detection of cancer and other disease. Biophysics research includes fundamental structural and biophysical investigations of immunoglobulins and key biological molecules using NMR, crystallographic, and x-ray and neutron small-angle scattering techniques. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  8. The Rise of Federally Funded Research and Development Centers

    Energy Technology Data Exchange (ETDEWEB)

    DALE,BRUCE C.; MOY,TIMOTHY D.

    2000-09-01

    Federally funded research and development centers (FFRDCS) area unique class of research and development (R and D) facilities that share aspects of private and public ownership. Some FFRDCS have been praised as national treasures, but FFRDCS have also been the focus of much criticism through the years. This paper traces the history of FFRDCS through four periods: (1) the World War II era, which saw the birth of federal R and D centers that would eventually become FFRDCS; (2) the early Cold War period, which exhibited a proliferation of FFRDCS despite their unclear legislative status and growing tension with an increasingly capable and assertive defense industry, (3) there-evaluation and retrenchment of FFRDCS in the 1960s and early 1970s, which resulted in a dramatic decline in the number of FFRDCS; and (4) the definition and codification of the FFRDC entity in the late 1970s and 1980s, when Congress and the executive branch worked together to formalize regulations to control FFRDCS. The paper concludes with observations on the status of FFRDCS at the end of the twentieth century.

  9. Dryden Flight Research Center Critical Chain Project Management Implementation

    Science.gov (United States)

    Hines, Dennis O.

    2012-01-01

    In Fiscal Year 2011 Dryden Flight Research Center (DFRC) implemented a new project management system called Critical Chain Project Management (CCPM). Recent NASA audits have found that the Dryden workforce is strained under increasing project demand and that multi-tasking has been carried to a whole new level at Dryden. It is very common to have an individual work on 10 different projects during a single pay period. Employee surveys taken at Dryden have identified work/life balance as the number one issue concerning employees. Further feedback from the employees indicated that project planning is the area needing the most improvement. In addition, employees have been encouraged to become more innovative, improve job skills, and seek ways to improve overall job efficiency. In order to deal with these challenges, DFRC management decided to adopt the CCPM system that is specifically designed to operate in a resource constrained multi-project environment. This paper will discuss in detail the rationale behind the selection of CCPM and the goals that will be achieved through this implementation. The paper will show how DFRC is tailoring the CCPM system to the flight research environment as well as laying out the implementation strategy. Results of the ongoing implementation will be discussed as well as change management challenges and organizational cultural changes. Finally this paper will present some recommendations on how this system could be used by selected NASA projects or centers.

  10. The Center for Aerospace Research: A NASA Center of Excellence at North Carolina Agricultural and Technical State University

    Science.gov (United States)

    Lai, Steven H.-Y.

    1992-01-01

    This report documents the efforts and outcomes of our research and educational programs at NASA-CORE in NCA&TSU. The goal of the center was to establish a quality aerospace research base and to develop an educational program to increase the participation of minority faculty and students in the areas of aerospace engineering. The major accomplishments of this center in the first year are summarized in terms of three different areas, namely, the center's research programs area, the center's educational programs area, and the center's management area. In the center's research programs area, we focus on developing capabilities needed to support the development of the aerospace plane and high speed civil transportation system technologies. In the educational programs area, we developed an aerospace engineering option program ready for university approval.

  11. Translational Partnership Development Lead | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Frederick National Laboratory for Cancer Research (FNLCR) is a Federally Funded Research and Development Center operated by Leidos Biomedical Research, Inc on behalf of the National Cancer Institute (NCI). The staff of FNLCR support the NCI’s mission in the fight against cancer and HIV/AIDS. Currently we are seeking a Translational Partnership Development Lead (TPDL) who will work closely with the Office of Translational Resources (OTR) within the Office of the Director (OD) of NCI’s Center for Cancer Research (CCR) to facilitate the successful translation of CCR’s basic and preclinical research advances into new therapeutics and diagnostics. The TPDL with be strategically aligned within FNLCR’s Partnership Development Office (PDO), to maximally leverage the critical mass of expertise available within the PDO. CCR comprises the basic and clinical components of the NCI’s Intramural Research Program (IRP) and consists of ~230 basic and clinical Investigators located at either the NIH main campus in Bethesda or the NCI-Frederick campus. CCR Investigators are focused primarily on cancer and HIV/AIDS, with special emphasis on the most challenging and important high-risk/high-reward problems driving the fields. (See https://ccr.cancer.gov for a full delineation of CCR Investigators and their research activities.) The process of developing research findings into new clinical applications is high risk, complex, variable, and requires multiple areas of expertise seldom available within the confines of a single Investigator’s laboratory. To accelerate this process, OTR serves as a unifying force within CCR for all aspects of translational activities required to achieve success and maintain timely progress. A key aspect of OTR’s function is to develop and strengthen essential communications and collaborations within NIH, with extramural partners and with industry to bring together experts in chemistry, human subjects research

  12. Division of Biological and Medical Research research summary 1984-1985

    Energy Technology Data Exchange (ETDEWEB)

    Barr, S.H. (ed.)

    1985-08-01

    The Division of Biological and Medical Research at Argonne National Laboratory conducts multidisciplinary research aimed at defining the biological and medical hazards to man from energy technologies and new energy options. These technically oriented studies have a strong base in fundamental research in a variety of scientific disciplines, including molecular and cellular biology, biophysics, genetics, radiobiology, pharmacology, biochemistry, chemistry, environmental toxicology, and epidemiology. This research summary is organized into six parts. The first five parts reflect the Divisional structure and contain the scientific program chapters, which summarize the activities of the individual groups during the calendar year 1984 and the first half of 1985. To provide better continuity and perspective, previous work is sometimes briefly described. Although the summaries are short, efforts have been made to indicate the range of research activities for each group.

  13. Division of Biological and Medical Research research summary 1984-1985

    International Nuclear Information System (INIS)

    Barr, S.H.

    1985-08-01

    The Division of Biological and Medical Research at Argonne National Laboratory conducts multidisciplinary research aimed at defining the biological and medical hazards to man from energy technologies and new energy options. These technically oriented studies have a strong base in fundamental research in a variety of scientific disciplines, including molecular and cellular biology, biophysics, genetics, radiobiology, pharmacology, biochemistry, chemistry, environmental toxicology, and epidemiology. This research summary is organized into six parts. The first five parts reflect the Divisional structure and contain the scientific program chapters, which summarize the activities of the individual groups during the calendar year 1984 and the first half of 1985. To provide better continuity and perspective, previous work is sometimes briefly described. Although the summaries are short, efforts have been made to indicate the range of research activities for each group

  14. Epigenetics in radiation biology: a new research frontier

    International Nuclear Information System (INIS)

    Agarwal, Sural

    2014-01-01

    The number of people that receive exposure to ionizing radiation (IR) via occupational, diagnostic, or treatment-related modalities is progressively rising. It is now accepted that the negative consequences of radiation exposure are not isolated to exposed cells or individuals. Exposure to IR can induce genome instability in the germ line, and is further associated with transgenerational genomic instability in the off spring of exposed males. The exact molecular mechanisms for transgenerational genome instability have yet to be elucidated, although there is support for it being an epigenetically induced phenomenon. This review is centered on the long-term biological effects associated with IR exposure, mainly focusing on the epigentic mechanisms and also some facts about whether dental radiology (IOPA, OPG, CT, MRI, CBCT) can lead to carcinogenesis. (author)

  15. Research Projects for Interrogations of Biological Systems: Training for the Development of Novel Radiotracers

    Energy Technology Data Exchange (ETDEWEB)

    Jurisson, Silvia S. [Univ. of Missouri, Columbia, MO (United States); Lever, Susan Z. [Univ. of Missouri, Columbia, MO (United States); Robertson, J. David [Univ. of Missouri, Columbia, MO (United States)

    2016-10-04

    This grant was situated at the University of Missouri to train Ph.D. scientists in radiochemistry and synthetic chemistry in conjunction with Faculty from the Interdisciplinary Plant Group, Division of Biological Sciences, the MU Research Reactor Center, Molecular Biology and the Radiopharmaceutical Sciences Institute. This project was collaborative with Brookhaven National Laboratory (Richard Ferrieri, PI). Projects for the Ph.D. candidates included novel probe development for peptides, nucleosides, small molecules or radiometals, the direct use of radiometals as probes, or nuclear techniques for analysis. The projects for the postdoctoral fellow involved synthetic chemistry for the preparation of precursors for novel tracers that will be radiolabeled with 18F or other appropriate radionuclides. The skill sets of our team members allowed us to prepare probes with positron or single photon emitters, as well as ones that are dual-labeled (fluorescent and radiolabeled). We focused our technical advances to those that will be broadly applicable to any research field.

  16. Research Projects for Interrogations of Biological Systems: Training for the Development of Novel Radiotracers

    International Nuclear Information System (INIS)

    Jurisson, Silvia S.; Lever, Susan Z.; Robertson, J. David

    2016-01-01

    This grant was situated at the University of Missouri to train Ph.D. scientists in radiochemistry and synthetic chemistry in conjunction with Faculty from the Interdisciplinary Plant Group, Division of Biological Sciences, the MU Research Reactor Center, Molecular Biology and the Radiopharmaceutical Sciences Institute. This project was collaborative with Brookhaven National Laboratory (Richard Ferrieri, PI). Projects for the Ph.D. candidates included novel probe development for peptides, nucleosides, small molecules or radiometals, the direct use of radiometals as probes, or nuclear techniques for analysis. The projects for the postdoctoral fellow involved synthetic chemistry for the preparation of precursors for novel tracers that will be radiolabeled with "1"8F or other appropriate radionuclides. The skill sets of our team members allowed us to prepare probes with positron or single photon emitters, as well as ones that are dual-labeled (fluorescent and radiolabeled). We focused our technical advances to those that will be broadly applicable to any research field.

  17. Division of Biological and Medical Research annual report 1978

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.W. (ed.)

    1978-01-01

    The research during 1978 in the Division of Biological and Medical Research, Argonne National Laboratory, is summarized. Studies related to nuclear energy include responses of beagles to continuous low-level /sup 60/Co gamma radiation, and development of leukemic indicators; comparison of lifetime effects in mice of low-level neutron and /sup 60/Co gamma radiation; genetic effects of high LET radiations; and metabolic and therapeutic studies of heavy metals. Studies of nonnuclear energy sources deal with characterization and toxicological evaluation of effluents of fluidized bed combustion and coal gasification; electrical storage systems; electric fields associated with energy transmission; and development of population projection models and assessment of human risk. Basic research studies include fundamental structural and biophysical investigations; circadian rhythms; mutagenesis in bacteria and mammalian cells; cell killing, damage, and repair in mammalian cells; carcinogenesis and cocarcinogenesis; the use of liposomes as biological carriers; and studies of environmental influences on life-span, physiological performance, and circadian cycles. In the area of medical development, proteins in urine and tissues of normal and diseased humans are analyzed, and advanced analytical procedures for use of stable isotopes in clinical research and diagnosis are developed and applied. The final sections of the report cover support facilities, educational activities, the seminar program, staff talks, and staff publications.

  18. Division of Biological and Medical Research annual technical report 1982

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1983-05-01

    This report summarizes research during 1982 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Carcinogenesis address mechanisms of chemical and radiation carcinogenesis including the processes of tumor initiation and promotion. The studies employ rat liver and mouse skin models as well as human rodent cell culture systems. The use of liposomes for metal mobilization is also explored. Low Level Radiation studies include delineation of the hematopoietic and other responses of dogs to continuous low level gamma irradiation, comparison of lifetime effects in mice of low level neutron and gamma irradiation, and study of the genetic effects of high LET radiation. Molecular Biology research develops two-dimensional electrophoresis systems for diagnosis and detection of cancer and other diseases. Fundamental structural and biophysical investigations of immunoglobulins and other key proteins are included, as are studies of cell growth, and of molecular and cellular effects of solar uv light. Research in Toxicology uses cellular, physiological, whole animal, and chronobiological end points and chemical separations to elucidate mechanisms and evaluate hazards of coal conversion by-products, actinides, and toxic metals. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies

  19. Division of Biological and Medical Research annual technical report 1982

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.W. (ed.)

    1983-05-01

    This report summarizes research during 1982 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Carcinogenesis address mechanisms of chemical and radiation carcinogenesis including the processes of tumor initiation and promotion. The studies employ rat liver and mouse skin models as well as human rodent cell culture systems. The use of liposomes for metal mobilization is also explored. Low Level Radiation studies include delineation of the hematopoietic and other responses of dogs to continuous low level gamma irradiation, comparison of lifetime effects in mice of low level neutron and gamma irradiation, and study of the genetic effects of high LET radiation. Molecular Biology research develops two-dimensional electrophoresis systems for diagnosis and detection of cancer and other diseases. Fundamental structural and biophysical investigations of immunoglobulins and other key proteins are included, as are studies of cell growth, and of molecular and cellular effects of solar uv light. Research in Toxicology uses cellular, physiological, whole animal, and chronobiological end points and chemical separations to elucidate mechanisms and evaluate hazards of coal conversion by-products, actinides, and toxic metals. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  20. Division of Biological and Medical Research annual report 1978

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1978-01-01

    The research during 1978 in the Division of Biological and Medical Research, Argonne National Laboratory, is summarized. Studies related to nuclear energy include responses of beagles to continuous low-level 60 Co gamma radiation, and development of leukemic indicators; comparison of lifetime effects in mice of low-level neutron and 60 Co gamma radiation; genetic effects of high LET radiations; and metabolic and therapeutic studies of heavy metals. Studies of nonnuclear energy sources deal with characterization and toxicological evaluation of effluents of fluidized bed combustion and coal gasification; electrical storage systems; electric fields associated with energy transmission; and development of population projection models and assessment of human risk. Basic research studies include fundamental structural and biophysical investigations; circadian rhythms; mutagenesis in bacteria and mammalian cells; cell killing, damage, and repair in mammalian cells; carcinogenesis and cocarcinogenesis; the use of liposomes as biological carriers; and studies of environmental influences on life-span, physiological performance, and circadian cycles. In the area of medical development, proteins in urine and tissues of normal and diseased humans are analyzed, and advanced analytical procedures for use of stable isotopes in clinical research and diagnosis are developed and applied. The final sections of the report cover support facilities, educational activities, the seminar program, staff talks, and staff publications

  1. Twenty-fifth anniversary of the Karlsruhe Nuclear Research Center

    International Nuclear Information System (INIS)

    Harde, R.

    1981-01-01

    The Karlsruhe Nuclear Research Center was founded on July 19, 1956. The initial company, in which the Federal Republic of Germany held a 30% interest, the State of Baden-Wuerttemberg 20%, and German industry 50%, was founded mainly for the purposes of building and operating a German-designed research reactor. In 1959, the Gesellschaft fuer Kernforschung mbH was founded for execution of the research and development activities, in which the Federal Republic of Germany held 75%, the State of Baden-Wuerttemberg 25% of the shares. The two companies were merged in 1963, after industry had donated its holdings in the initial company to the new company. In 1972, the financial holdings of the Federal Government were raised to 90%. On January 1, 1978, the company was named Kernforschungszentrum Karlsruhe GmbH (KfK). Over the past 25 years, KfK has received approx. DM 7 billion out of public funds. Important milestones in the development of nuclear technology in the Federal Republic contributed by KfK include the development of the fast breeder line and responsibility for construction of the first German fast breeder reactor, KNK; development of reprocessing technologies and responsibility for construction of the first German reprocessing plant, WAK; development of a uranium enrichment technique (separation nozzle method); important contributions to reactor safety, fusion research, and training in nuclear technology. (orig.) [de

  2. Use of synchrotron radiation in radiation biology research

    International Nuclear Information System (INIS)

    Yamada, Takeshi

    1981-01-01

    Synchrotron radiation (SR) holds great expectation as a new research tool in the new areas of material science, because it has the continuous spectral distribution from visible light to X-ray, and its intensity is 10 2 to 10 3 times as strong as that of conventional radiation sources. In the National Laboratory for High Energy Physics, a synchrotron radiation experimental facility has been constructed, which will start operation in fiscal 1982. With this SR, the photons having the wavelength in undeveloped region from vacuum ultraviolet to soft X-ray are obtained as intense mono-wavelength light. The SR thus should contribute to the elucidation of the fundamentals in the biological action of radiation. The following matters are described: synchrotron radiation, experimental facility using SR, electron storage ring, features of SR, photon factory plan and synchrotron radiation experimental facility, utilization of SR in radiation biology field. (J.P.N.)

  3. Biologically Weighted Quantities in Radiotherapy: an EMRP Joint Research Project

    Directory of Open Access Journals (Sweden)

    Rabus Hans

    2014-01-01

    Full Text Available Funded within the European Metrology Research Programme (EMRP [1], the joint research project “Biologically weighted quantities in radiotherapy” (BioQuaRT [2] aims to develop measurement and simulation techniques for determining the physical properties of ionising particle tracks on different length scales (about 2 nm to 10 μm, and to investigate the correlation of these track structure characteristics with the biological effects of radiation at the cellular level. Work package 1 develops micro-calorimeter prototypes for the direct measurement of lineal energy and will characterise their response for different ion beams by experiment and modelling. Work package 2 develops techniques to measure particle track structure on different length scales in the nanometre range as well as a measurement device integrating a silicon microdosimeter and a nanodosimeter. Work package 3 investigates the indirect effects of radiation based on probes for quantifying particular radical and reactive oxygen species (ROS. Work package 4 focuses on the biological aspects of radiation damage and will produce data on initial DNA damage and late effects for radiotherapy beams of different qualities. Work package 5 provides evaluated data sets of DNA cross-sections and develops a multi-scale model to address microscopic and nanometric track structure properties. The project consortium includes three linked researchers holding so-called Researcher Excellence Grants, who carry out ancillary investigations such as developing and benchmarking a new biophysical model for induction of early radiation damage and developing methods for the translation of quantities derived from particle track structure to clinical applications in ion beam therapy.

  4. Nurse Practitioner/Physician Assistant | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  5. Multi-Vehicle Cooperative Control Research at the NASA Armstrong Flight Research Center, 2000-2014

    Science.gov (United States)

    Hanson, Curt

    2014-01-01

    A brief introductory overview of multi-vehicle cooperative control research conducted at the NASA Armstrong Flight Research Center from 2000 - 2014. Both flight research projects and paper studies are included. Since 2000, AFRC has been almost continuously pursuing research in the areas of formation flight for drag reduction and automated cooperative trajectories. An overview of results is given, including flight experiments done on the FA-18 and with the C-17. Other multi-vehicle cooperative research is discussed, including small UAV swarming projects and automated aerial refueling.

  6. A research on the enhancement of research management efficiency for the division of research, Korea cancer center hospital

    International Nuclear Information System (INIS)

    Lee, S. W.; Ma, K. H.; Kim, J. R.; Lee, D. C.; Lee, J. H.

    1999-06-01

    The research activities of Korea Cancer Center Hospital have increased for the past a few years just in proportion to the increase of research budget, but the assisting manpower of the office of research management has never been increased and the indications are that the internal and external circumstances will not allow the recruitment for a fairly long time. It has, therefore, become inevitable to enhance the work efficiency of the office by analyzing the administrative research assistance system, finding out problems and inefficiency factors, and suggesting possible answers to them. The office of research management and international cooperation has conducted this research to suggest possible ways to facilitate the administrative support for the research activities of Korea Cancer Center Hospital By analyzing the change of research budget, organization of the division of research and administrative support, manpower, and the administrative research supporting system of other institutes, we suggested possible ways to enhance the work efficiency for administrative research support and developed a relative database program. The research report will serve as a data for the organization of research support division when the Radiation Medicine Research Center is established. The database program has already been used for research budget management

  7. Reorganizing the General Clinical Research Center to improve the clinical and translational research enterprise.

    Science.gov (United States)

    Allen, David; Ripley, Elizabeth; Coe, Antoinette; Clore, John

    2013-12-01

    In 2010, Virginia Commonwealth University (VCU) was granted a Clinical and Translational Science Award which prompted reorganization and expansion of their clinical research infrastructure. A case study approach is used to describe the implementation of a business and cost recovery model for clinical and translational research and the transformation of VCU's General Clinical Research Center and Clinical Trials Office to a combined Clinical Research Services entity. We outline the use of a Plan, Do, Study, Act cycle that facilitated a thoughtful transition process, which included the identification of required changes and cost recovery processes for implementation. Through this process, the VCU Center for Clinical and Translational Research improved efficiency, increased revenue recovered, reduced costs, and brought a high level of fiscal responsibility through financial reporting.

  8. Building research infrastructure in community health centers: a Community Health Applied Research Network (CHARN) report.

    Science.gov (United States)

    Likumahuwa, Sonja; Song, Hui; Singal, Robbie; Weir, Rosy Chang; Crane, Heidi; Muench, John; Sim, Shao-Chee; DeVoe, Jennifer E

    2013-01-01

    This article introduces the Community Health Applied Research Network (CHARN), a practice-based research network of community health centers (CHCs). Established by the Health Resources and Services Administration in 2010, CHARN is a network of 4 community research nodes, each with multiple affiliated CHCs and an academic center. The four nodes (18 individual CHCs and 4 academic partners in 9 states) are supported by a data coordinating center. Here we provide case studies detailing how CHARN is building research infrastructure and capacity in CHCs, with a particular focus on how community practice-academic partnerships were facilitated by the CHARN structure. The examples provided by the CHARN nodes include many of the building blocks of research capacity: communication capacity and "matchmaking" between providers and researchers; technology transfer; research methods tailored to community practice settings; and community institutional review board infrastructure to enable community oversight. We draw lessons learned from these case studies that we hope will serve as examples for other networks, with special relevance for community-based networks seeking to build research infrastructure in primary care settings.

  9. Information center as a link between basic and applied research

    International Nuclear Information System (INIS)

    Pearlstein, S.

    1976-01-01

    The National Neutron Cross Section Center (NNCSC) concerns itself with neutron physics information of a basic and applied nature. Computerized files of bibliography to the neutron physics literature, and of experimental and evaluated neutron data are maintained. The NNCSC coordinates a national effort, the Cross Section Evaluation Working Group (CSEWG) with participants from government, private, and academic institutions, to establish a computerized reference data base Evaluated Nuclear Data File (ENDF/B) for national programs. The ENDF/B is useful to basic research because it contains recommended values based on the best available measurements and is often used as reference data for normalization and analysis of experiments. For applied use the reference data are extended through nuclear model calculations or nuclear systematics to include all data of interest with standardized processing codes facilitating the use of ENDF/B in certain types of computations. Initially the main application of ENDF/B was power reactor and shield design and only neutron data were evaluated but due to the fact that for many applications both neutron and nonneutron data are required, ENDF/B has been extended in scope to include radioactive decay data and radiation spectra for the burnup and after decay heat of fission products and photon interaction data for gamma ray transport calculations. Cooperation with other centers takes place both nationally and internationally

  10. Langley Research Center Utility Risk from Future Climate Change

    Science.gov (United States)

    De Young, Russell J.; Ganoe, Rene

    2015-01-01

    The successful operation of NASA Langley Research Center (LaRC) depends on services provided by several public utility companies. These include Newport News Waterworks, Dominion Virginia Power, Virginia Natural Gas and Hampton Roads Sanitation District. LaRC's plan to respond to future climate change should take into account how these companies plan to avoid interruption of services while minimizing cost to the customers. This report summarizes our findings from publicly available documents on how each company plans to respond. This will form the basis for future planning for the Center. Our preliminary findings show that flooding and severe storms could interrupt service from the Waterworks and Sanitation District but the potential is low due to plans in place to address climate change on their system. Virginia Natural Gas supplies energy to produce steam but most current steam comes from the Hampton trash burning plant, thus interruption risk is low. Dominion Virginia Power does not address climate change impacts on their system in their public reports. The potential interruption risk is considered to be medium. The Hampton Roads Sanitation District is projecting a major upgrade of their system to mitigate clean water inflow and infiltration. This will reduce infiltration and avoid overloading the pump stations and treatment plants.

  11. Operating The Central Process Systems At Glenn Research Center

    Science.gov (United States)

    Weiler, Carly P.

    2004-01-01

    As a research facility, the Glenn Research Center (GRC) trusts and expects all the systems, controlling their facilities to run properly and efficiently in order for their research and operations to occur proficiently and on time. While there are many systems necessary for the operations at GRC, one of those most vital systems is the Central Process Systems (CPS). The CPS controls operations used by GRC's wind tunnels, propulsion systems lab, engine components research lab, and compressor, turbine and combustor test cells. Used widely throughout the lab, it operates equipment such as exhausters, chillers, cooling towers, compressors, dehydrators, and other such equipment. Through parameters such as pressure, temperature, speed, flow, etc., it performs its primary operations on the major systems of Electrical Dispatch (ED), Central Air Dispatch (CAD), Central Air Equipment Building (CAEB), and Engine Research Building (ERB). In order for the CPS to continue its operations at Glenn, a new contract must be awarded. Consequently, one of my primary responsibilities was assisting the Source Evaluation Board (SEB) with the process of awarding the recertification contract of the CPS. The job of the SEB was to evaluate the proposals of the contract bidders and then to present their findings to the Source Selecting Official (SSO). Before the evaluations began, the Center Director established the level of the competition. For this contract, the competition was limited to those companies classified as a small, disadvantaged business. After an industry briefing that explained to qualified companies the CPS and type of work required, each of the interested companies then submitted proposals addressing three components: Mission Suitability, Cost, and Past Performance. These proposals were based off the Statement of Work (SOW) written by the SEB. After companies submitted their proposals, the SEB reviewed all three components and then presented their results to the SSO. While the

  12. Karlsruhe Nuclear Research Center. Progress report on research and development work in 1987

    International Nuclear Information System (INIS)

    1988-01-01

    This summary of R and D work is the scientific annual report to be prepared by the research center in compliance with its statutes. The material is arranged by items of main activities, as given in the overall R and D programme set up for the research center. The various reports prepared by the individual institutes and principal departments are presented under their relevant subject headings. The annual report is intended to demonstrate the progress achieved in the tasks and activities assigned by the R and D programme of the research center, by referring to the purposes and goals stated in the programme, showing the joint or separate efforts and achievements of the institutes. Details and results of activities are found in the scientific-technical publications given in the bibliographical survey, and in the internal primary surveys. The main activities of the research center include the following: Fast Breeder Project (PSB), Nuclear Fusion Project (PKF), Separation Nozzle Project (TDV), and Reprocessing and Waste Treatment Project (PWA), Ultimate Disposal of Radioactive Waste (ELA), Environment and Safety (U and S), Solids and Materials (FM), Nuclear and Particle Physics (KTP), Microtechniques (MT), Materials Handling (HT), Other Research Activities (SF). Organisational aspects and institutes and the list of publications conclude the report. (orig./HK) [de

  13. Research in thermal biology: Burning questions for coldwater stream fishes

    Science.gov (United States)

    McCullough, D.A.; Bartholow, J.M.; Jager, H.I.; Beschta, R.L.; Cheslak, E.F.; Deas, M.L.; Ebersole, J.L.; Foott, J.S.; Johnson, S.L.; Marine, K.R.; Mesa, M.G.; Petersen, J.H.; Souchon, Y.; Tiffan, K.F.; Wurtsbaugh, W.A.

    2009-01-01

    With the increasing appreciation of global warming impacts on ecological systems, in addition to the myriad of land management effects on water quality, the number of literature citations dealing with the effects of water temperature on freshwater fish has escalated in the past decade. Given the many biological scales at which water temperature effects have been studied, and the growing need to integrate knowledge from multiple disciplines of thermal biology to fully protect beneficial uses, we held that a survey of the most promising recent developments and an expression of some of the remaining unanswered questions with significant management implications would best be approached collectively by a diverse research community. We have identified five specific topic areas of renewed research where new techniques and critical thought could benefit coldwater stream fishes (particularly salmonids): molecular, organism, population/species, community and ecosystem, and policy issues in water quality. Our hope is that information gained through examination of recent research fronts linking knowledge at various scales will prove useful in managing water quality at a basin level to protect fish populations and whole ecosystems. Standards of the past were based largely on incipient lethal and optimum growth rate temperatures for fish species, while future standards should consider all integrated thermal impacts to the organism and ecosystem. ?? Taylor and Francis Group, LLC.

  14. 2004 research briefs :Materials and Process Sciences Center.

    Energy Technology Data Exchange (ETDEWEB)

    Cieslak, Michael J.

    2004-01-01

    This report is the latest in a continuing series that highlights the recent technical accomplishments associated with the work being performed within the Materials and Process Sciences Center. Our research and development activities primarily address the materials-engineering needs of Sandia's Nuclear-Weapons (NW) program. In addition, we have significant efforts that support programs managed by the other laboratory business units. Our wide range of activities occurs within six thematic areas: Materials Aging and Reliability, Scientifically Engineered Materials, Materials Processing, Materials Characterization, Materials for Microsystems, and Materials Modeling and Simulation. We believe these highlights collectively demonstrate the importance that a strong materials-science base has on the ultimate success of the NW program and the overall DOE technology portfolio.

  15. An example of a United States Nuclear Research Center

    International Nuclear Information System (INIS)

    Bhattacharyya, S. K.

    1999-01-01

    Under the likely scenario in which public support for nuclear energy remains low and fossil fuels continue to be abundant and cheap, government supported nuclear research centers must adapt their missions to ensure that they tackle problems of current significance. It will be critical to be multidisciplinary, to generate economic value, and to apply nuclear competencies to current problems. Addressing problems in nuclear safety, D and D, nuclear waste management, nonproliferation, isotope production are a few examples of current needs in the nuclear arena. Argonne's original mission, to develop nuclear reactor technology, was a critical need for the U.S. in 1946. It would be wise to recognize that this mission was a special instance of a more general one--to apply unique human and physical capital to long term, high risk technology development in response to society's needs. International collaboration will enhance the collective chances for success as the world moves into the 21st century

  16. New research resources at the Bloomington Drosophila Stock Center.

    Science.gov (United States)

    Cook, Kevin R; Parks, Annette L; Jacobus, Luke M; Kaufman, Thomas C; Matthews, Kathleen A

    2010-01-01

    The Bloomington Drosophila Stock Center (BDSC) is a primary source of Drosophila stocks for researchers all over the world. It houses over 27,000 unique fly lines and distributed over 160,000 samples of these stocks this past year. This report provides a brief overview of significant recent events at the BDSC with a focus on new stock sets acquired in the past year, including stocks for phiC31 transformation, RNAi knockdown of gene expression, and SNP and quantitative trait loci discovery. We also describe additions to sets of insertions and molecularly defined chromosomal deficiencies, the creation of a new Deficiency Kit, and planned additions of X chromosome duplication sets.

  17. Quality management system of Saraykoy Nuclear Research and Training center

    International Nuclear Information System (INIS)

    Gurellier, R.; Akchay, S.; Zararsiz, S.

    2014-01-01

    Full text : Technical competence and national/international acceptance of independency of laboratories is ensured by going through accreditations. It provides decreasing the risk of a slowdown in international trade due to unnecessary repetition of testing and analyses. It also eliminates the cost of additional experiments and analyses. Saraykoy Nuclear Research and Training Center (SANAEM) has performed intensive studies to establish an effective and well-functioning QMS (Quality Management System) by full accordance with the requirements of ISO/IEC 17025, since the begining of 2006. Laboratories, especially serving to public health studies and important trade duties require urgent accreditation. In this regard, SANAEM has established a quality management system and performed accreditation studies

  18. Distance Learning With NASA Lewis Research Center's Learning Technologies Project

    Science.gov (United States)

    Petersen, Ruth

    1998-01-01

    The NASA Lewis Research Center's Learning Technologies Project (LTP) has responded to requests from local school district technology coordinators to provide content for videoconferencing workshops. Over the past year we have offered three teacher professional development workshops that showcase NASA Lewis-developed educational products and NASA educational Internet sites. In order to determine the direction of our involvement with distance learning, the LTP staff conducted a survey of 500 U.S. schools. We received responses from 72 schools that either currently use distance learning or will be using distance learning in 98-99 school year. The results of the survey are summarized in the article. In addition, the article provides information on distance learners, distance learning technologies, and the NASA Lewis LTP videoconferencing workshops. The LTP staff will continue to offer teacher development workshops through videoconferencing during the 98-99 school year. We hope to add workshops on new educational products as they are developed at NASA Lewis.

  19. Quality in research centers; Calidad en centros de investigacion

    Energy Technology Data Exchange (ETDEWEB)

    Colin Orozco, Leticia [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico)

    2000-07-01

    In order to be able to survive and to have successful in the globalized market, all the organizations must make an effort in learning and understanding the language of the international trade, of the standards that govern it and the technical specifications that are handled for the quality assurance of products and services. In this paper the importance that the implementation of standards ISO-9000 in the research centers has, is presented. [Spanish] Para poder sobrevivir y tener exito en el mercado globalizado todas las organizaciones tienen que esforzarse en el aprendizaje y comprension del lenguaje del comercio internacional, de las normas que lo rigen y de las especificaciones tecnicas que se manejan para asegurar la calidad de los productos y servicios. En este articulo se presenta la importancia que tiene la implantacion de las normas ISO-9000 en los centros de investigacion.

  20. Sustainability indicators to nuclear research centers in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Simone F.; Feliciano, Vanusa Maria D.; Barreto, Alberto A., E-mail: symonfonseca@yahoo.com.br, E-mail: vmfj@cdtn.br, E-mail: aab@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2015-07-01

    The relevance and applicability of sustainability indicators have been discussed in various international and national debates through forums, conferences, seminars and lectures. The information obtained from the use of these indicators is essential to the decision-making process, contributing to the creation of discussion channels and interaction with society; also it is useful for the design and implementation of environmental education programs, perception and risk communication. So far, at least in Brazil, existing indicators for the nuclear area are related only to power generation, as performance and safety in radioactive waste management. According to this reality we see the need to build indicators that contribute to the assessment of environmental, social, cultural, economic and institutional performance of a nuclear innovation and research institute in Brazil. This work aims to highlight, through literature review, the importance of developing sustainability indicators appropriate to nuclear research centers in Brazil, revealing how much they are strategic to measuring the sustainability of these endeavours. The main finding, after the literature review, is that this type of indicator is important not only to identify positive or negative impacts of a project focused on the research and innovation of nuclear area, but also for assessment of his commitment to the sustainable development. (author)

  1. Molecularly Engineered Energy Materials, an Energy Frontier Research Center

    Energy Technology Data Exchange (ETDEWEB)

    Ozolins, Vidvuds [Univ. of California, Los Angeles, CA (United States). Materials Science and Engineering Dept.

    2016-09-28

    Molecularly Engineered Energy Materials (MEEM) was established as an interdisciplinary cutting-edge UCLA-based research center uniquely equipped to attack the challenge of rationally designing, synthesizing and testing revolutionary new energy materials. Our mission was to achieve transformational improvements in the performance of materials via controlling the nano-and mesoscale structure using selectively designed, earth-abundant, inexpensive molecular building blocks. MEEM has focused on materials that are inherently abundant, can be easily assembled from intelligently designed building blocks (molecules, nanoparticles), and have the potential to deliver transformative economic benefits in comparison with the current crystalline-and polycrystalline-based energy technologies. MEEM addressed basic science issues related to the fundamental mechanisms of carrier generation, energy conversion, as well as transport and storage of charge and mass in tunable, architectonically complex materials. Fundamental understanding of these processes will enable rational design, efficient synthesis and effective deployment of novel three-dimensional material architectures for energy applications. Three interrelated research directions were initially identified where these novel architectures hold great promise for high-reward research: solar energy generation, electrochemical energy storage, and materials for CO2 capture. Of these, the first two remained throughout the project performance period, while carbon capture was been phased out in consultation and with approval from BES program manager.

  2. Sustainability indicators to nuclear research centers in Brazil

    International Nuclear Information System (INIS)

    Alves, Simone F.; Feliciano, Vanusa Maria D.; Barreto, Alberto A.

    2015-01-01

    The relevance and applicability of sustainability indicators have been discussed in various international and national debates through forums, conferences, seminars and lectures. The information obtained from the use of these indicators is essential to the decision-making process, contributing to the creation of discussion channels and interaction with society; also it is useful for the design and implementation of environmental education programs, perception and risk communication. So far, at least in Brazil, existing indicators for the nuclear area are related only to power generation, as performance and safety in radioactive waste management. According to this reality we see the need to build indicators that contribute to the assessment of environmental, social, cultural, economic and institutional performance of a nuclear innovation and research institute in Brazil. This work aims to highlight, through literature review, the importance of developing sustainability indicators appropriate to nuclear research centers in Brazil, revealing how much they are strategic to measuring the sustainability of these endeavours. The main finding, after the literature review, is that this type of indicator is important not only to identify positive or negative impacts of a project focused on the research and innovation of nuclear area, but also for assessment of his commitment to the sustainable development. (author)

  3. Energy Frontier Research Center, Center for Materials Science of Nuclear Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Todd R. Allen, Director

    2011-04-01

    The Office of Science, Basic Energy Sciences, has funded the INL as one of the Energy Frontier Research Centers in the area of material science of nuclear fuels. This document is the required annual report to the Office of Science that outlines the accomplishments for the period of May 2010 through April 2011. The aim of the Center for Material Science of Nuclear Fuels (CMSNF) is to establish the foundation for predictive understanding of the effects of irradiation-induced defects on thermal transport in oxide nuclear fuels. The science driver of the center’s investigation is to understand how complex defect and microstructures affect phonon mediated thermal transport in UO2, and achieve this understanding for the particular case of irradiation-induced defects and microstructures. The center’s research thus includes modeling and measurement of thermal transport in oxide fuels with different levels of impurities, lattice disorder and irradiation-induced microstructure, as well as theoretical and experimental investigation of the evolution of disorder, stoichiometry and microstructure in nuclear fuel under irradiation. With the premise that thermal transport in irradiated UO2 is a phonon-mediated energy transport process in a crystalline material with defects and microstructure, a step-by-step approach will be utilized to understand the effects of types of defects and microstructures on the collective phonon dynamics in irradiated UO2. Our efforts under the thermal transport thrust involved both measurement of diffusive phonon transport (an approach that integrates over the entire phonon spectrum) and spectroscopic measurements of phonon attenuation/lifetime and phonon dispersion. Our distinct experimental efforts dovetail with our modeling effort involving atomistic simulation of phonon transport and prediction of lattice thermal conductivity using the Boltzmann transport framework.

  4. Ongkharak Nuclear Research Center-the role of the consultant

    International Nuclear Information System (INIS)

    Jacobi, A.; De Haller, L.

    1998-01-01

    The Ongkharak Nuclear Research Center Project is known to have started on 26 June 1997. At that date the Contract for the turnkey delivery of the three nuclear facilities, the Reactor Island [RI] , Isotope Production Facility [IPF] and the Waste Processing and Storage Facilities [WPSF], was signed by the Office of the Atomic Energy for Peace [OAEP] with General Atomics [GA]. The involvement of Atomic Consultant - Electrowatt Engineering Ltd. (EWE) - already started more than 2 years earlier than the official start of this ambitious project. Since mid 1995 EWE has been serving in a variety of functions and has been requested to perform numerous tasks in support of OAEP. By acting in the function of the Consultant, EWE was aiming firstly to help the project to proceed as quickly as possible. Secondly EWE was overseeing constantly that the quality of the Center, once finished, will meet the present state of the art, will be licensable in Thailand (or elsewhere) and will be internationally recognised as a safe, reliable and modern research and production installation. The role of EWE covers a multitude of engineering disciplines, such as architecture; civil, mechanical, nuclear, I and C and electrical engineering; nuclear and reactor physics; chemistry and radiopharmacy; economy and price estimation. Besides, EWE has to use its skills in conducting and/or supervising large projects, e.g., by appropriate scheduling, QA surveys, licensing support, document control, etc. Furthermore, EWE is actively involved in know-how transfer to Thai engineers and scientists by working in close co-operation with OAEP's project personnel and - if required - by giving special training courses. This paper presents some highlights as well as routine activities performed by EWE so far in the Project

  5. Combined Neutron Center for European Research and Technology

    International Nuclear Information System (INIS)

    Lagniel, Jean-Michel

    2002-01-01

    High-power proton linacs are needed as driver for several applications, namely transmutation of nuclear waste using Accelerator Driven Systems (ADS), spallation neutron sources (ESS in Europe) and other fields of basic and applied research (next generation of radioactive ion beam facilities, neutrino factories, muon colliders, irradiation facilities for material testing...). The possible synergies among these projects will be pointed out and the feasibility study of high-power proton linac used as driver of a multi-user facility (CONCERT) will be presented. There was excellent scientific, technical and economic reasons to study a Combined Neutron Center for European Research and Technology (CONCERT) based on a high-power proton accelerator. Such an installation would serve condensed matter studies by spallation neutron scattering, a technological irradiation tool and R and D facility for an hybrid reactor demonstrator, a radioactive ion beam facility for nuclear physics, R and D developments for a muon/neutrino facility. The installation could therefore constitute a European center of excellence in the field of neutronics where a large number of scientific and technical executives could be trained. The CONCERT Project Team has performed the feasibility study of such a multi-user facility with: - a review of the beam needs for the different applications, - an analyze of their compatibility, - the definition of the scope of a site-independent project, - a selection of the most appropriate options regarding scientific, technical, financial, organizational and administrative aspects, - an estimation of the costs for construction, operation and the needs in manpower. The conceptual design report [17] is sufficiently detailed to minimize contingencies on those parts of the project having a large potential impact in terms of performances, costs or delays. (author)

  6. The countries and languages that dominate biological research at the beginning of the 21st century.

    Science.gov (United States)

    Monge-Nájera, Julian; Nielsen, Vanessa

    2005-01-01

    Traditionally, studies of scientific productivity are biased in two ways: they are based on Current Contents, an index centered in British and American journals, and they seldom correct for population size, ignoring the relative effort that each society places in research. We studied national productivity for biology using a more representative index, the Biological Abstracts, and analyzed both total and relative productivity. English dominates biological publications with 87% (no other individual language reaches 2%). If the USA is considered a region by itself, it occupies the first place in per capita production of biology papers, with at least twice the productivity of either Asia or Europe. Canada, Oceania and Latin America occupy an intermediate position. The global output of scientific papers is dominated by Europe, USA. Japan, Canada, China and India. When corrected for population size, the countries with the greatest productivity of biology papers are the Nordic nations, Israel, Switzerland, Netherlands, Australia, Saint Lucia and Montserrat. The predominance of English as the language of biological research found in this study shows a continuation of the trend initiated around the year 1900. The large relative productivity of the USA reflects the importance that American society gives to science as the basis for technological and economic development, but the USA's share of total scientific output has decreased from 44% in 1983 to 34% in 2002, while there is a greater growth of science in India, Japan and Latin America, among others. The increasing share obtained by China and India may reflect a recent change in attitude towards funding science. The leadership of Nordic nations, Israel, Switzerland, Netherlands and Australia can be explained by cultural attitude. Apparently, a positive trend is emerging in Latin America, where Chile improved its ranking in per capita productivity but Argentina, Costa Rica, Uruguay, Brazil and Cuba fell. Nevertheless, the

  7. Research Problems in Data Curation: Outcomes from the Data Curation Education in Research Centers Program

    Science.gov (United States)

    Palmer, C. L.; Mayernik, M. S.; Weber, N.; Baker, K. S.; Kelly, K.; Marlino, M. R.; Thompson, C. A.

    2013-12-01

    The need for data curation is being recognized in numerous institutional settings as national research funding agencies extend data archiving mandates to cover more types of research grants. Data curation, however, is not only a practical challenge. It presents many conceptual and theoretical challenges that must be investigated to design appropriate technical systems, social practices and institutions, policies, and services. This presentation reports on outcomes from an investigation of research problems in data curation conducted as part of the Data Curation Education in Research Centers (DCERC) program. DCERC is developing a new model for educating data professionals to contribute to scientific research. The program is organized around foundational courses and field experiences in research and data centers for both master's and doctoral students. The initiative is led by the Graduate School of Library and Information Science at the University of Illinois at Urbana-Champaign, in collaboration with the School of Information Sciences at the University of Tennessee, and library and data professionals at the National Center for Atmospheric Research (NCAR). At the doctoral level DCERC is educating future faculty and researchers in data curation and establishing a research agenda to advance the field. The doctoral seminar, Research Problems in Data Curation, was developed and taught in 2012 by the DCERC principal investigator and two doctoral fellows at the University of Illinois. It was designed to define the problem space of data curation, examine relevant concepts and theories related to both technical and social perspectives, and articulate research questions that are either unexplored or under theorized in the current literature. There was a particular emphasis on the Earth and environmental sciences, with guest speakers brought in from NCAR, National Snow and Ice Data Center (NSIDC), and Rensselaer Polytechnic Institute. Through the assignments, students

  8. Caenorhabditis elegans, a Biological Model for Research in Toxicology.

    Science.gov (United States)

    Tejeda-Benitez, Lesly; Olivero-Verbel, Jesus

    2016-01-01

    Caenorhabditis elegans is a nematode of microscopic size which, due to its biological characteristics, has been used since the 1970s as a model for research in molecular biology, medicine, pharmacology, and toxicology. It was the first animal whose genome was completely sequenced and has played a key role in the understanding of apoptosis and RNA interference. The transparency of its body, short lifespan, ability to self-fertilize and ease of culture are advantages that make it ideal as a model in toxicology. Due to the fact that some of its biochemical pathways are similar to those of humans, it has been employed in research in several fields. C. elegans' use as a biological model in environmental toxicological assessments allows the determination of multiple endpoints. Some of these utilize the effects on the biological functions of the nematode and others use molecular markers. Endpoints such as lethality, growth, reproduction, and locomotion are the most studied, and usually employ the wild type Bristol N2 strain. Other endpoints use reporter genes, such as green fluorescence protein, driven by regulatory sequences from other genes related to different mechanisms of toxicity, such as heat shock, oxidative stress, CYP system, and metallothioneins among others, allowing the study of gene expression in a manner both rapid and easy. These transgenic strains of C. elegans represent a powerful tool to assess toxicity pathways for mixtures and environmental samples, and their numbers are growing in diversity and selectivity. However, other molecular biology techniques, including DNA microarrays and MicroRNAs have been explored to assess the effects of different toxicants and samples. C. elegans has allowed the assessment of neurotoxic effects for heavy metals and pesticides, among those more frequently studied, as the nematode has a very well defined nervous system. More recently, nanoparticles are emergent pollutants whose toxicity can be explored using this nematode

  9. Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements

    Science.gov (United States)

    Kohl, Alain; Pondeville, Emilie; Schnettler, Esther; Crisanti, Andrea; Supparo, Clelia; Christophides, George K.; Kersey, Paul J.; Maslen, Gareth L.; Takken, Willem; Koenraadt, Constantianus J. M.; Oliva, Clelia F.; Busquets, Núria; Abad, F. Xavier; Failloux, Anna-Bella; Levashina, Elena A.; Wilson, Anthony J.; Veronesi, Eva; Pichard, Maëlle; Arnaud Marsh, Sarah; Simard, Frédéric; Vernick, Kenneth D.

    2016-01-01

    Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is increasingly common. Novel tools for genetic manipulation of vectors, use of Wolbachia endosymbiotic bacteria, and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies, adding to strong interest in vector biology and genetics as well as vector–pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructure investment should be informed by the research community. A survey initiated by the European Horizon 2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key activities that are needed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such activities to be carried out. We summarize the most important findings of the survey which in particular reflect the priorities of researchers in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations. PMID:27677378

  10. Final priority; National Institute on Disability and Rehabilitation Research--Rehabilitation Engineering Research Centers. Final priority.

    Science.gov (United States)

    2014-07-09

    The Assistant Secretary for Special Education and Rehabilitative Services announces a priority under the Disability and Rehabilitation Research Projects and Centers Program administered by the National Institute on Disability and Rehabilitation Research (NIDRR). Specifically, we announce a priority for a Rehabilitation Engineering Research Center (RERC) on Improving the Accessibility, Usability, and Performance of Technology for Individuals who are Deaf or Hard of Hearing. The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2014 and later years. We take this action to focus research attention on an area of national need. We intend the priority to contribute to improving the accessibility, usability, and performance of technology for individuals who are deaf or hard of hearing.

  11. A research plan based on high intensity proton accelerator Neutron Science Research Center

    International Nuclear Information System (INIS)

    Mizumoto, Motoharu

    1997-01-01

    A plan called Neutron Science Research Center (NSRC) has been proposed in JAERI. The center is a complex composed of research facilities based on a proton linac with an energy of 1.5GeV and an average current of 10mA. The research facilities will consist of Thermal/Cold Neutron Facility, Neutron Irradiation Facility, Neutron Physics Facility, OMEGA/Nuclear Energy Facility, Spallation RI Beam Facility, Meson/Muon Facility and Medium Energy Experiment Facility, where high intensity proton beam and secondary particle beams such as neutron, pion, muon and unstable radio isotope (RI) beams generated from the proton beam will be utilized for innovative researches in the fields on nuclear engineering and basic sciences. (author)

  12. A research plan based on high intensity proton accelerator Neutron Science Research Center

    Energy Technology Data Exchange (ETDEWEB)

    Mizumoto, Motoharu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-03-01

    A plan called Neutron Science Research Center (NSRC) has been proposed in JAERI. The center is a complex composed of research facilities based on a proton linac with an energy of 1.5GeV and an average current of 10mA. The research facilities will consist of Thermal/Cold Neutron Facility, Neutron Irradiation Facility, Neutron Physics Facility, OMEGA/Nuclear Energy Facility, Spallation RI Beam Facility, Meson/Muon Facility and Medium Energy Experiment Facility, where high intensity proton beam and secondary particle beams such as neutron, pion, muon and unstable radio isotope (RI) beams generated from the proton beam will be utilized for innovative researches in the fields on nuclear engineering and basic sciences. (author)

  13. Applied high-speed imaging for the icing research program at NASA Lewis Research Center

    Science.gov (United States)

    Slater, Howard; Owens, Jay; Shin, Jaiwon

    1992-01-01

    The Icing Research Tunnel at NASA Lewis Research Center provides scientists a scaled, controlled environment to simulate natural icing events. The closed-loop, low speed, refrigerated wind tunnel offers the experimental capability to test for icing certification requirements, analytical model validation and calibration techniques, cloud physics instrumentation refinement, advanced ice protection systems, and rotorcraft icing methodology development. The test procedures for these objectives all require a high degree of visual documentation, both in real-time data acquisition and post-test image processing. Information is provided to scientific, technical, and industrial imaging specialists as well as to research personnel about the high-speed and conventional imaging systems will be on the recent ice protection technology program. Various imaging examples for some of the tests are presented. Additional imaging examples are available from the NASA Lewis Research Center's Photographic and Printing Branch.

  14. Innovation in Flight: Research of the NASA Langley Research Center on Revolutionary Advanced Concepts for Aeronautics

    Science.gov (United States)

    Chambers, Joseph R.

    2005-01-01

    The goal of this publication is to provide an overview of the topic of revolutionary research in aeronautics at Langley, including many examples of research efforts that offer significant potential benefits, but have not yet been applied. The discussion also includes an overview of how innovation and creativity is stimulated within the Center, and a perspective on the future of innovation. The documentation of this topic, especially the scope and experiences of the example research activities covered, is intended to provide background information for future researchers.

  15. Assessment team report on flight-critical systems research at NASA Langley Research Center

    Science.gov (United States)

    Siewiorek, Daniel P. (Compiler); Dunham, Janet R. (Compiler)

    1989-01-01

    The quality, coverage, and distribution of effort of the flight-critical systems research program at NASA Langley Research Center was assessed. Within the scope of the Assessment Team's review, the research program was found to be very sound. All tasks under the current research program were at least partially addressing the industry needs. General recommendations made were to expand the program resources to provide additional coverage of high priority industry needs, including operations and maintenance, and to focus the program on an actual hardware and software system that is under development.

  16. "Biology Education"--An Emerging Interdisciplinary Area of Research

    Science.gov (United States)

    Rutledge, Michael

    2013-01-01

    The growing number of faculty positions in biology education, the formation of professional societies focused specifically on biology education, and the increasing number of publications in biology education over the past decade

  17. Researchers studying alternative to bladder removal for bladder cancer patients | Center for Cancer Research

    Science.gov (United States)

    A new phase I clinical trial conducted by researchers at the Center for Cancer Research (CCR) is evaluating the safety and tolerability, or the degree to which any side effects can be tolerated by patients, of a two-drug combination as a potential alternative to bladder removal for bladder cancer patients. The trial targets patients with non-muscle invasive bladder cancer (NMIBC) whose cancers have stopped responding to traditional therapies. Read more...

  18. Reducing Losses from Wind-Related Natural Perils: Research at the IBHS Research Center

    OpenAIRE

    Standohar-Alfano, Christine D.; Estes, Heather; Johnston, Tim; Morrison, Murray J.; Brown-Giammanco, Tanya M.

    2017-01-01

    The capabilities of the Insurance Institute for Business & Home Safety (IBHS) Research Center full-scale test chamber are described in detail. This research facility allows complete full-scale structures to be tested. Testing at full-scale allows vulnerabilities of structures to be evaluated with fewer assumptions than was previously possible. Testing buildings under realistic elevated wind speeds has the potential to isolate important factors that influence the performance of components, pot...

  19. Critical Appraisal of Translational Research Models for Suitability in Performance Assessment of Cancer Centers

    NARCIS (Netherlands)

    Rajan, Abinaya; Sullivan, Richard; Bakker, Suzanne; van Harten, Willem H.

    2012-01-01

    Background. Translational research is a complex cumulative process that takes time. However, the operating environment for cancer centers engaged in translational research is now financially insecure. Centers are challenged to improve results and reduce time from discovery to practice innovations.

  20. 2010 Tetrapyrroles, Chemistry & Biology of Gordon Research Conference

    Energy Technology Data Exchange (ETDEWEB)

    Angela Wilks

    2010-07-30

    The objective of the Chemistry & Biology of Tetrapyrroles Gordon Conference is to bring together researchers from diverse disciplines that otherwise would not interact. By bringing biologists, chemists, engineers and clinicians with a common interest in tetrapyrroles the conference provides a forum for cross-disciplinary ideas and collaboration. The perspective provided by biologists, chemists, and clinicians working in fields such as newly discovered defects in human porphyrin metabolism, the myriad of strategies for light harvesting in photosynthetic organisms, novel tetrapyrroles that serve as auxiliary chromophores or enzyme cofactors, synthetic strategies in the design of novel tetrapyrrole scaffolds, and tetrapyrrole based cell signaling and regulatory systems, makes this conference unique in the field. Over the years the growing evidence for the role of tetrapyrroles and their reactive intermediates in cell signaling and regulation has been of increasing importance at this conference. The 2010 conference on Chemistry & Biology of Tetrapyrroles will focus on many of these new frontiers as outlined in the preliminary program listed. Speakers will emphasize unpublished results and new findings in the field. The oral sessions will be followed by the highly interactive afternoon poster sessions. The poster sessions provide all conferees with the opportunity to present their latest research and to exchange ideas in a more informal setting. As in the past, this opportunity will continue during the nightly social gathering that takes place in the poster hall following the evening lectures. All conferees are encouraged to submit and present posters. At the conference the best poster in the areas of biology, chemistry and medicine will be selected by a panel of previous conference chairs.

  1. Research program on the biological effects of oil pollution

    International Nuclear Information System (INIS)

    Barrett, R.T.

    1991-12-01

    A national research program on the biological effects of oil pollution (FOBO) was initiated by the Norwegian Ministry of Environment in October 1983 in the light of the increasing oil exploration and production activity in the North Sea and northern Norwegian waters. Ambitions were high and five main fields of research were suggested: Seabirds, fish (incl. salmon), marine mammals, the littoral zone and plankton. However, due to the lack of interest on the part of other potential financers, e.g. the Ministry of Fisheries and the oil companies, to participate, the four-year programme had to be limited to the following three topics: Seabirds around bruding colonies and at sea; Higher plants along the shoreline; The littoral zone. The program ran from the autumn of 1985 to the end of 1989 and this report summarizes the main results and conclusions of each project. 95 refs., 52 figs., 9 tabs

  2. BCTR: Biological and Chemical Technologies Research 1994 annual summary report

    Energy Technology Data Exchange (ETDEWEB)

    Petersen, G.

    1995-02-01

    The annual summary report presents the fiscal year (FY) 1994 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). Although the OIT was reorganized in 1991 and AICD no longer exists, this document reports on efforts conducted under the former structure. The annual summary report for 1994 (ASR 94) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization, selected technical and programmatic highlights for 1994; detailed descriptions of individual projects; a listing of program output, including a bibliography of published work; patents, and awards arising from work supported by BCTR.

  3. Application of the selected physical methods in biological research

    Directory of Open Access Journals (Sweden)

    Jaromír Tlačbaba

    2013-01-01

    Full Text Available This paper deals with the application of acoustic emission (AE, which is a part of the non-destructive methods, currently having an extensive application. This method is used for measuring the internal defects of materials. AE has a high potential in further research and development to extend the application of this method even in the field of process engineering. For that matter, it is the most elaborate acoustic emission monitoring in laboratory conditions with regard to external stimuli. The aim of the project is to apply the acoustic emission recording the activity of bees in different seasons. The mission is to apply a new perspective on the behavior of colonies by means of acoustic emission, which collects a sound propagation in the material. Vibration is one of the integral part of communication in the community. Sensing colonies with the support of this method is used for understanding of colonies biological behavior to stimuli clutches, colony development etc. Simulating conditions supported by acoustic emission monitoring system the illustrate colonies activity. Collected information will be used to represent a comprehensive view of the life cycle and behavior of honey bees (Apis mellifera. Use of information about the activities of bees gives a comprehensive perspective on using of acoustic emission in the field of biological research.

  4. Methods of 15N tracer research in biological systems

    International Nuclear Information System (INIS)

    Hirschberg, K.; Faust, H.

    1985-01-01

    The application of the stable isotope 15 N is of increasing importance in different scientific disciplines, especially in medicine, agriculture, and the biosciences. The close correlation between the growing interest and improvements of analytical procedures resulted in remarkable advances in the 15 N tracer technique. On the basis of the latest results of 15 N tracer research in life sciences and agriculture methods of 15 N tracer research in biological systems are compiled. The 15 N methodology is considered under three headings: Chemical analysis with a description of methods of sample preparation (including different separation and isolation methods for N-containing substances of biological and agricultural origin) and special procedures converting ammonia to molecular nitrogen. Isotopic analysis with a review on the most important methods of isotopic analysis of nitrogen: mass spectrometry (including the GC-MS technique), emission spectrometry, NMR spectroscopy, and other analytical procedures. 15 N-tracer techniques with a consideration of the role of the isotope dilution analysis as well as different labelling techniques and the mathematical interpretation of tracer data (modelling, N turnover experiments). In these chapters also sources of errors in chemical and isotopic analysis, the accuracy of the different methods and its importance on tracer experiments are discussed. Procedures for micro scale 15 N analysis and aspects of 15 N analysis on the level of natural abundance are considered. Furthermore some remarks on isotope effects in 15 N tracer experiments are made. (author)

  5. Naturalistic Cognition: A Research Paradigm for Human-Centered Design

    Directory of Open Access Journals (Sweden)

    Peter Storkerson

    2010-01-01

    Full Text Available Naturalistic thinking and knowing, the tacit, experiential, and intuitive reasoning of everyday interaction, have long been regarded as inferior to formal reason and labeled primitive, fallible, subjective, superstitious, and in some cases ineffable. But, naturalistic thinking is more rational and definable than it appears. It is also relevant to design. Inquiry into the mechanisms of naturalistic thinking and knowledge can bring its resources into focus and enable designers to create better, human-centered designs for use in real-world settings. This article makes a case for the explicit, formal study of implicit, naturalistic thinking within the fields of design. It develops a framework for defining and studying naturalistic thinking and knowledge, for integrating them into design research and practice, and for developing a more integrated, consistent theory of knowledge in design. It will (a outline historical definitions of knowledge, attitudes toward formal and naturalistic thinking, and the difficulties presented by the co-presence of formal and naturalistic thinking in design, (b define and contrast formal and naturalistic thinking as two distinct human cognitive systems, (c demonstrate the importance of naturalistic cognition in formal thinking and real-world judgment, (d demonstrate methods for researching naturalistic thinking that can be of use in design, and (e briefly discuss the impact on design theory of admitting naturalistic thinking as valid, systematic, and knowable.

  6. Introduction of hot cell facility in research center Rez - Poster

    International Nuclear Information System (INIS)

    Petrickova, A.; Srba, O.; Miklos, M.; Svoboda, P.

    2015-01-01

    This poster presents the hot cell facility which is being constructed as part of the SUSEN project at the Rez research center (Czech Republic). Within this project a new complex of 10 hot cells and one semi-hot cell will be built. There will be 8 gamma hot cells and 2 alpha hot cells. In each hot cell a hermetic, removable box made of stainless steel will home different type of devices. The hot cells and semi hot cell will be equipped with devices for processing samples (cutting, welding, drilling, machining) as well as equipment for testing (sample preparation area, stress testing machine, fatigue machine, electromechanical creep machine, high frequency resonance pulsator...) and equipment for studying material microstructure (nano-indenter with nano-scratch tester and scanning electron microscope). An autoclave with water loop, installed in a cell will allow mechanical testing in control environment of water, pressure and temperature. A scheme shows the equipment of each cell. This hot laboratory will be able to cover all the process to study radioactive materials: receiving the material, the preparation of the samples, mechanical testing and microstructure observation. Our hot cells will be close to the research nuclear reactor LVR-15 and new irradiation facility (high irradiation by cobalt source) is planned to be built within the SUSEN project

  7. U.S, Department of Energy's Bioenergy Research Centers An Overview of the Science

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-07-01

    . This program is bringing together scientists in diverse fields to understand the complex biology underlying solutions to DOE missions in energy production, environmental remediation, and climate change science. New interdisciplinary research communities are emerging, as are knowledgebases and scientific and computational resources critical to advancing large-scale, genome-based biology. To focus the most advanced biotechnology-based resources on the biological challenges of biofuel production, DOE established three Bioenergy Research Centers (BRCs) in September 2007. Each center is pursuing the basic research underlying a range of high-risk, high-return biological solutions for bioenergy applications. Advances resulting from the BRCs will provide the knowledge needed to develop new biobased products, methods, and tools that the emerging biofuel industry can use. The scientific rationale for these centers and for other fundamental genomic research critical to the biofuel industry was established at a DOE workshop involving members of the research community (see sidebar, Biofuel Research Plan, below). The DOE BRCs have developed automated, high-throughput analysis pipelines that will accelerate scientific discovery for biology-based biofuel research. The three centers, which were selected through a scientific peer-review process, are based in geographically diverse locations--the Southeast, the Midwest, and the West Coast--with partners across the nation. DOE's Oak Ridge National Laboratory leads the BioEnergy Science Center (BESC) in Tennessee; the University of Wisconsin-Madison leads the Great Lakes Bioenergy Research Center (GLBRC); and DOE's Lawrence Berkeley National Laboratory leads the DOE Joint BioEnergy Institute (JBEI) in California. Each center represents a multidisciplinary partnership with expertise spanning the physical and biological sciences, including genomics, microbial and plant biology, analytical chemistry, computational biology and

  8. Fostering Social Determinants of Health Transdisciplinary Research: The Collaborative Research Center for American Indian Health

    Directory of Open Access Journals (Sweden)

    Amy J. Elliott

    2015-12-01

    Full Text Available The Collaborative Research Center for American Indian Health (CRCAIH was established in September 2012 as a unifying structure to bring together tribal communities and health researchers across South Dakota, North Dakota and Minnesota to address American Indian/Alaska Native (AI/AN health disparities. CRCAIH is based on the core values of transdisciplinary research, sustainability and tribal sovereignty. All CRCAIH resources and activities revolve around the central aim of assisting tribes with establishing and advancing their own research infrastructures and agendas, as well as increasing AI/AN health research. CRCAIH is comprised of three divisions (administrative; community engagement and innovation; research projects, three technical cores (culture, science and bioethics; regulatory knowledge; and methodology, six tribal partners and supports numerous multi-year and one-year pilot research projects. Under the ultimate goal of improving health for AI/AN, this paper describes the overarching vision and structure of CRCAIH, highlighting lessons learned in the first three years.

  9. Final priorities; National Institute on Disability and Rehabilitation Research--Disability and Rehabilitation Research Projects and Centers Program--Rehabilitation Engineering Research Centers. Final priorities.

    Science.gov (United States)

    2013-06-11

    The Assistant Secretary for Special Education and Rehabilitative Services announces priorities under the Disability and Rehabilitation Research Projects and Centers Program administered by the National Institute on Disability and Rehabilitation Research (NIDRR). Specifically, we announce priorities for a Rehabilitation Engineering Research Center (RERC) on Rehabilitation Strategies, Techniques, and Interventions (Priority 1), Information and Communication Technologies Access (Priority 2), Individual Mobility and Manipulation (Priority 3), and Physical Access and Transportation (Priority 4). The Assistant Secretary may use one or more of these priorities for competitions in fiscal year (FY) 2013 and later years. We take this action to focus research attention on areas of national need. We intend these priorities to improve community living and participation, health and function, and employment outcomes of individuals with disabilities.

  10. Building Climate Resilience at NASA Ames Research Center

    Science.gov (United States)

    Iraci, L. T.; Mueller, C.; Podolske, J. R.; Milesi, C.

    2016-12-01

    NASA Ames Research Center, located at the southern end of the San Francisco Bay (SFB) estuary, has identified three primary vulnerabilities to changes in climate. The Ames Climate Adaptation Science Investigator (CASI) workgroup has studied each of these challenges to operations and the potential exposure of infrastructure and employees to an increased frequency of hazards. Sea level rise inundation scenarios for the SFB Area generally refer to projected scenarios in mean sea level rather than changes in extreme tides that could occur during future storm conditions. In the summer of 2014, high resolution 3-D mapping of the low-lying portion of Ames was performed. Those data are integrated with improved sea level inundation scenarios to identify the buildings, basements and drainage systems potentially affected. We will also identify the impacts of sea level and storm surge effects on transportation to and from the Center. This information will help Center management develop future master plans. Climate change will also lead to changes in temperature, storm frequency and intensity. These changes have potential impacts on localized floods and ecosystems, as well as on electricity and water availability. Over the coming decades, these changes will be imposed on top of ongoing land use and land cover changes, especially those deriving from continued urbanization and increase in impervious surface areas. These coupled changes have the potential to create a series of cascading impacts on ecosystems, including changes in primary productivity and disturbance of hydrological properties and increased flood risk. The majority of the electricity used at Ames is supplied by hydroelectric dams, which will be influenced by reductions in precipitation or changes in the timing or phase of precipitation which reduces snow pack. Coupled with increased demand for summertime air conditioning and other cooling needs, NASA Ames is at risk for electricity shortfalls. To assess the

  11. The National Extreme Events Data and Research Center (NEED)

    Science.gov (United States)

    Gulledge, J.; Kaiser, D. P.; Wilbanks, T. J.; Boden, T.; Devarakonda, R.

    2014-12-01

    The Climate Change Science Institute at Oak Ridge National Laboratory (ORNL) is establishing the National Extreme Events Data and Research Center (NEED), with the goal of transforming how the United States studies and prepares for extreme weather events in the context of a changing climate. NEED will encourage the myriad, distributed extreme events research communities to move toward the adoption of common practices and will develop a new database compiling global historical data on weather- and climate-related extreme events (e.g., heat waves, droughts, hurricanes, etc.) and related information about impacts, costs, recovery, and available research. Currently, extreme event information is not easy to access and is largely incompatible and inconsistent across web sites. NEED's database development will take into account differences in time frames, spatial scales, treatments of uncertainty, and other parameters and variables, and leverage informatics tools developed at ORNL (i.e., the Metadata Editor [1] and Mercury [2]) to generate standardized, robust documentation for each database along with a web-searchable catalog. In addition, NEED will facilitate convergence on commonly accepted definitions and standards for extreme events data and will enable integrated analyses of coupled threats, such as hurricanes/sea-level rise/flooding and droughts/wildfires. Our goal and vision is that NEED will become the premiere integrated resource for the general study of extreme events. References: [1] Devarakonda, Ranjeet, et al. "OME: Tool for generating and managing metadata to handle BigData." Big Data (Big Data), 2014 IEEE International Conference on. IEEE, 2014. [2] Devarakonda, Ranjeet, et al. "Mercury: reusable metadata management, data discovery and access system." Earth Science Informatics 3.1-2 (2010): 87-94.

  12. Joint Center for Satellite Data Assimilation Overview and Research Activities

    Science.gov (United States)

    Auligne, T.

    2017-12-01

    In 2001 NOAA/NESDIS, NOAA/NWS, NOAA/OAR, and NASA, subsequently joined by the US Navy and Air Force, came together to form the Joint Center for Satellite Data Assimilation (JCSDA) for the common purpose of accelerating the use of satellite data in environmental numerical prediction modeling by developing, using, and anticipating advances in numerical modeling, satellite-based remote sensing, and data assimilation methods. The primary focus was to bring these advances together to improve operational numerical model-based forecasting, under the premise that these partners have common technical and logistical challenges assimilating satellite observations into their modeling enterprises that could be better addressed through cooperative action and/or common solutions. Over the last 15 years, the JCSDA has made and continues to make major contributions to operational assimilation of satellite data. The JCSDA is a multi-agency U.S. government-owned-and-operated organization that was conceived as a venue for the several agencies NOAA, NASA, USAF and USN to collaborate on advancing the development and operational use of satellite observations into numerical model-based environmental analysis and forecasting. The primary mission of the JCSDA is to "accelerate and improve the quantitative use of research and operational satellite data in weather, ocean, climate and environmental analysis and prediction systems." This mission is fulfilled through directed research targeting the following key science objectives: Improved radiative transfer modeling; new instrument assimilation; assimilation of humidity, clouds, and precipitation observations; assimilation of land surface observations; assimilation of ocean surface observations; atmospheric composition; and chemistry and aerosols. The goal of this presentation is to briefly introduce the JCSDA's mission and vision, and to describe recent research activities across various JCSDA partners.

  13. A new apparatus at hyper irradiation research facility at the Atomic Research Center, University of Tokyo

    Energy Technology Data Exchange (ETDEWEB)

    Shibata, Hiromi; Iwai, Takeo; Narui, Makoto; Omata, Takao [Tokyo Univ. (Japan). Research Center for Nuclear Science and Technology

    1996-12-01

    In the hyper irradiation research facility at the Atomic Research Center, the University of Tokyo, following apparatuses were newly installed for accelerator relating apparatus on 1995 fiscal year; (1) Hyper ion microbeam analysis apparatus, (2) Fourier conversion infrared microscopy, (3) Pico second two-dimensional fluorescence measuring apparatus, (4) Femto second wave-length reversible pulse laser radiation apparatus, and others. In addition to double irradiation, pulse beam irradiation experiment and so forth characteristic in conventional hyper irradiation research apparatus, upgrading of material irradiation experiments using these new apparatuses are intended. (G.K.)

  14. A new apparatus at hyper irradiation research facility at the Atomic Research Center, University of Tokyo

    International Nuclear Information System (INIS)

    Shibata, Hiromi; Iwai, Takeo; Narui, Makoto; Omata, Takao

    1996-01-01

    In the hyper irradiation research facility at the Atomic Research Center, the University of Tokyo, following apparatuses were newly installed for accelerator relating apparatus on 1995 fiscal year; 1) Hyper ion microbeam analysis apparatus, 2) Fourier conversion infrared microscopy, 3) Pico second two-dimensional fluorescence measuring apparatus, 4) Femto second wave-length reversible pulse laser radiation apparatus, and others. In addition to double irradiation, pulse beam irradiation experiment and so forth characteristic in conventional hyper irradiation research apparatus, upgrading of material irradiation experiments using these new apparatuses are intended. (G.K.)

  15. The joint center for energy storage research: A new paradigm for battery research and development

    Energy Technology Data Exchange (ETDEWEB)

    Crabtree, George [Joint Center for Energy Storage Research, Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439, USA and University of Illinois at Chicago, 845 W. Taylor Street, Chicago, IL 60607 (United States)

    2015-03-30

    The Joint Center for Energy Storage Research (JCESR) seeks transformational change in transportation and the electricity grid driven by next generation high performance, low cost electricity storage. To pursue this transformative vision JCESR introduces a new paradigm for battery research: integrating discovery science, battery design, research prototyping and manufacturing collaboration in a single highly interactive organization. This new paradigm will accelerate the pace of discovery and innovation and reduce the time from conceptualization to commercialization. JCESR applies its new paradigm exclusively to beyond-lithium-ion batteries, a vast, rich and largely unexplored frontier. This review presents JCESR's motivation, vision, mission, intended outcomes or legacies and first year accomplishments.

  16. The joint center for energy storage research: A new paradigm for battery research and development

    International Nuclear Information System (INIS)

    Crabtree, George

    2015-01-01

    The Joint Center for Energy Storage Research (JCESR) seeks transformational change in transportation and the electricity grid driven by next generation high performance, low cost electricity storage. To pursue this transformative vision JCESR introduces a new paradigm for battery research: integrating discovery science, battery design, research prototyping and manufacturing collaboration in a single highly interactive organization. This new paradigm will accelerate the pace of discovery and innovation and reduce the time from conceptualization to commercialization. JCESR applies its new paradigm exclusively to beyond-lithium-ion batteries, a vast, rich and largely unexplored frontier. This review presents JCESR's motivation, vision, mission, intended outcomes or legacies and first year accomplishments

  17. Research Summaries: The 11th Biennial Rivkin Center Ovarian Cancer Research Symposium.

    Science.gov (United States)

    Armstrong, Deborah K

    2017-11-01

    In September 2016, the 11th biennial ovarian cancer research symposium was presented by the Rivkin Center for Ovarian Cancer and the American Association for Cancer Research. The 2016 symposium focused on 4 broad areas of research: Mechanisms of Initiation and Progression of Ovarian Cancer, Tumor Microenvironment and Models of Ovarian Cancer, Detection and Prevention of Ovarian Cancer, and Novel Therapeutics for Ovarian Cancer. The presentations and abstracts from each of these areas are reviewed in this supplement to the International Journal of Gynecologic Oncology.

  18. Division of Biological and Medical Research annual report, 1980

    International Nuclear Information System (INIS)

    Rosenthal, M.W.

    1981-08-01

    The research during 1980 in the Division of Biological and Medical Research, Argonne National Laboratory, is summarized. Research related to nuclear energy includes the delineation, in the beagle, of the responses to continuous low level 60 Co gamma radiation and the development of cellular indicators of preclinical phases of leukemia; comparison of lifetime effects in mice of low level neutron and 60 Co gamma radiation; studies of the genetic effects of high LET radiations; and studies of the gastrointestinal absorption of the actinide elements. Research related to nonuclear energy sources deals with characterization and toxicological evaluation of process streams and effluents of coal gasification; with electrical storage systems; and electric fields associated with energy transmission. Proteins in human urine and selected tissues are examined by two-dimensional electrophoresis to detect disease and pollutant related changes. Assessment of human risk associated with nuclearing collective dose commitment will result in more attention being paid to potential releases of radionuclides at relatively short times after disposal

  19. Scientific and technical photography at NASA Langley Research Center

    Science.gov (United States)

    Davidhazy, Andrew

    1994-12-01

    As part of my assignment connected with the Scientific and Technical Photography & Lab (STPL) at the NASA Langley Research Center I conducted a series of interviews and observed the day to day operations of the STPL with the ultimate objective of becoming exposed first hand to a scientific and technical photo/imaging department for which my school prepares its graduates. I was also asked to share my observations with the staff in order that these comments and observations might assist the STPL to better serve its customers. Meetings with several individuals responsible for various wind tunnels and with a group that provides photo-optical instrumentation services at the Center gave me an overview of the services provided by the Lab and possible areas for development. In summary form these are some of the observations that resulted from the interviews and daily contact with the STPL facility. (1) The STPL is perceived as a valuable and almost indispensable service group within the organization. This comment was invariably made by everyone. Everyone also seemed to support the idea that the STPL continue to provide its current level of service and quality. (2) The STPL generally is not perceived to be a highly technically oriented group but rather as a provider of high quality photographic illustration and documentation services. In spite of the importance and high marks assigned to the STPL there are several observations that merit consideration and evaluation for possible inclusion into the STPL's scope of expertise and future operating practices. (1) While the care and concern for artistic rendition of subjects is seen as laudable and sometimes valuable, the time that this often requires is seen as interfering with keeping the tunnels operating at maximum productivity. Tunnel managers would like to shorten down-time due to photography, have services available during evening hours and on short notice. It may be of interest to the STPL that tunnel managers are

  20. A Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm

    Energy Technology Data Exchange (ETDEWEB)

    Aderem, Alan; Adkins, Joshua N.; Ansong, Charles; Galagan, James; Kaiser, Shari; Korth, Marcus J.; Law, G. L.; McDermott, Jason E.; Proll, Sean; Rosenberger, Carrie; Schoolnik, Gary; Katze, Michael G.

    2011-02-01

    The 20th century was marked by extraordinary advances in our understanding of microbes and infectious disease, but pandemics remain, food and water borne illnesses are frequent, multi-drug resistant microbes are on the rise, and the needed drugs and vaccines have not been developed. The scientific approaches of the past—including the intense focus on individual genes and proteins typical of molecular biology—have not been sufficient to address these challenges. The first decade of the 21st century has seen remarkable innovations in technology and computational methods. These new tools provide nearly comprehensive views of complex biological systems and can provide a correspondingly deeper understanding of pathogen-host interactions. To take full advantage of these innovations, the National Institute of Allergy and Infectious Diseases recently initiated the Systems Biology Program for Infectious Disease Research. As participants of the Systems Biology Program we think that the time is at hand to redefine the pathogen-host research paradigm.

  1. Advances, gaps, and future prospects in biological soil crust research

    Science.gov (United States)

    Weber, Bettina; Büdel, Burkhard; Belnap, Jayne

    2017-04-01

    Research progress has led to the understanding that biological soil crusts (biocrusts) are often complete miniature ecosystems comprising a variety of photosynthesizers (cyanobacteria, algae, lichens, bryophytes), decomposers like bacteria, fungi, and archaea, and heterotrophic organisms, like protozoa, nematodes, and microarthropods feeding on them. Biocrusts are one of the oldest terrestrial ecosystems, playing central roles in the structure and functioning of dryland ecosystems and presumably also influencing global biogeochemical cycles. On the other hand, biocrusts have been shown to be highly sensitive to global change, being easily destroyed by mechanical disturbance and severely threatened by minor changes in climate patterns. Despite the large increase in biocrust research, we still see major knowledge gaps which need to be tackled. Considering biodiversity studies, there are major regions of potential biocrust occurrence, where hardly any studies have been conducted. Molecular identification techniques are increasingly employed, but genetically characterized entities need to be linked with morphologically identified organisms to identify their ecological roles. Although there is a large body of research on the role of biocrusts in water and nutrient budgets, we are still far from closing the overall cycles. Results suggest that not all mechanisms have been identified, yet, leading to sometimes contradictory results between different studies. Knowledge on how to minimize impact to biocrusts during surface-disturbing activities has hardly been gained, and despite research efforts, instructions on effective biocrust restoration are still exemplary. In order to fill these research gaps, novel scientific approaches are needed. We expect that global research networks could be extremely helpful to answer scientific questions by tackling them within different regions, utilizing the same methodological techniques. Global networks could also be used for long

  2. Life lines: An art history of biological research around 1800.

    Science.gov (United States)

    Bruhn, Matthias

    2011-12-01

    Around 1800, the scientific "illustrator" emerged as a new artistic profession in Europe. Artists were increasingly sought after in order to picture anatomical dissections and microscopic observations and to translate drawings into artworks for books and journals. By training and technical expertise, they introduced a particular kind of knowledge into scientific perception that also shaped the common image of nature. Illustrations of scientific publications, often undervalued as a biased interpretation of facts and subordinate to logic and description, thus convey an 'art history' of science in its own right, relevant both for the understanding of biological thought around 1800 as well as for the development of the arts and their historiography. The article is based on an analysis of botanical treatises produced for the Göttingen Society of Sciences in 1803, during an early phase of microscopic cell research, in order to determine the constitutive role of artistic knowledge and the media employed for the visualization and conceptualization of biological issues. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Growth Analysis of Cancer Biology Research, 2000-2011

    Directory of Open Access Journals (Sweden)

    Keshava,

    2015-09-01

    Full Text Available Methods and Material: The PubMed database was used for retrieving data on 'cancer biology.' Articles were downloaded from the years 2000 to 2011. The articles were classified chronologically and transferred to a spreadsheet application for analysis of the data as per the objectives of the study. Statistical Method: To investigate the nature of growth of articles via exponential, linear, and logistics tests. Result: The year wise analysis of the growth of articles output shows that for the years 2000 to 2005 and later there is a sudden increase in output, during the years 2006 to 2007 and 2008 to 2011. The high productivity of articles during these years may be due to their significance in cancer biology literature, having received prominence in research. Conclusion: There is an obvious need for better compilations of statistics on numbers of publications in the years from 2000 to 2011 on various disciplines on a worldwide scale, for informed critical assessments of the amount of new knowledge contributed by these publications, and for enhancements and refinements of present Scientometric techniques (citation and publication counts, so that valid measures of knowledge growth may be obtained. Only then will Scientometrics be able to provide accurate, useful descriptions and predictions of knowledge growth.

  4. NASA Ames Research Center 60 MW Power Supply Modernization

    Science.gov (United States)

    Choy, Yuen Ching; Ilinets, Boris V.; Miller, Ted; Nagel, Kirsten (Technical Monitor)

    2001-01-01

    The NASA Ames Research Center 60 MW DC Power Supply was built in 1974 to provide controlled DC power for the Thermophysics Facility Arc Jet Laboratory. The Power Supply has gradually losing reliability due to outdated technology and component life limitation. NASA has decided to upgrade the existing rectifier modules with contemporary high-power electronics and control equipment. NASA plans to complete this project in 2001. This project includes a complete replacement of obsolete thyristor stacks in all six rectifier modules and rectifier bridge control system. High power water-cooled thyristors and freewheeling diodes will be used. The rating of each of the six modules will be 4000 A at 5500 V. The control firing angle signal will be sent from the Facility Control System to six modules via fiberoptic cable. The Power Supply control and monitoring system will include a Master PLC in the Facility building and a Slave PLC in each rectifier module. This system will also monitor each thyristor level in each stack and the auxiliary equipment.

  5. Incineration of radioactive wastes at the Nuclear Research Center Karlsruhe

    Energy Technology Data Exchange (ETDEWEB)

    Baehr, W; Hempelmann, W; Krause, H

    1976-06-01

    In 1971 a large incineration plant started operation in the Nuclear Research Center Karlsruhe. This plant is serving for routine incineration of up to 100 kg of combustible radioactive solids or 40 l of contaminated organic liquids and oils per hour. A dry off-gas cleaning system has been developed for this installation in which the fumes are cleaned by ceramic filter candles. After passing the filtering system and cooling, the off-gas is discharged directly through a stack. The activity concentration in the off-gas is measured by a continuous monitoring system. The ashes arising from the incineration are mixed with cement grout and filled into 200 l-drums. By this way approximately one drum of fixed ashes results from 100 drums of combustible wastes. During the first four years of operation, more than 4,000 m/sup 3/ of combustible solids and about 60 m/sup 3/ organic solvents have been incinerated in the plant. The operating experiences are presented.

  6. Extended Operation of Stirling Convertors at NASA Glenn Research Center

    Science.gov (United States)

    Oriti, Salvatore, M.

    2012-01-01

    NASA Glenn Research Center (GRC) has been supporting development of free-piston Stirling conversion technology for spaceflight electrical power generation since 1999. GRC has also been supporting the development of the Advanced Stirling Radioisotope Generator (ASRG) since 2006. A key element of the ASRG project is providing life, reliability, and performance data for the Advanced Stirling Convertor (ASC). The Thermal Energy Conversion branch at GRC is conducting extended operation of several free-piston Stirling convertors. The goal of this effort is to generate long-term performance data (tens of thousands of hours) on multiple units to build a life and reliability database. Currently, GRC is operating 18 convertors. This hardware set includes Technology Demonstration Convertors (TDCs) from Infinia Corporation, of which one pair (TDCs #13 and #14) has accumulated over 60,000 hr (6.8 years) of operation. Also under test are various Sunpower, Inc. convertors that were fabricated during the ASC development activity, including ASC-0, ASC-E (including those in the ASRG engineering unit), and ASC-E2. The ASC-E2s also completed, or are in progress of completing workmanship vibration testing, performance mapping, and extended operation. Two ASC-E2 units will also be used for durability testing, during which components will be stressed to levels above nominal mission usage. Extended operation data analyses from these tests are covered in this paper.

  7. Hypopharyngeal carcinoma: King Faisal Specialist Hospital and Research Center experience

    International Nuclear Information System (INIS)

    Mahasin, Z.; Khan, B.

    1996-01-01

    From 1975 to 1985, 202 patients with hypopharyngeal cancer were seen at King Faisal Specialist Hospital and Research Center (KFSHRC). The endoscopic investigation showed that 28.3% of these patients had postcricoid carcinoma; 19.85% had pyriform fossa carcinoma and 52.9% had involvement of both sites. The pathological diagnosis of all cases was squamous cell carcinoma type. The majority of the patients (62.98%) had T4 lesions, which showed a late presentation to KFSHRC. Information related to survival was available for a smaller number of patients to many lost-to-follow-up cases. The overall median survival time was 8.5 months (1-110 months). The survival rate for each site was calculated, as well as the staging of the disease and treatment modality used. It appeared that pyriform fossa (median 21 months) had the best survival rate. In addition the earlier the lesion was detected and the more aggressive the treatment applied, the better the survival rate. Fifty percent of the patients receiving radiation therapy and surgery had a five year survival arte. Factors other than smoking and/on drinking should be looked for in our community as predisposing to this disease in our population. (author)

  8. Two new research melters at the Savannah River Technology Center

    International Nuclear Information System (INIS)

    Gordon, J.R.; Coughlin, J.T.; Minichan, R.L.; Zamecnik, J.R.

    2000-01-01

    The Savannah River Technology Center (SRTC) is a US Department of Energy (DOE) complex leader in the development of vitrification technology. To maintain and expand this SRTC core technology, two new melter systems are currently under construction in SRTC. This paper discusses the development of these two new systems, which will be used to support current as well as future vitrification programs in the DOE complex. The first of these is the new minimelter, which is a joule-heated glass melter intended for experimental melting studies with nonradioactive glass waste forms. Testing will include surrogates of Defense Waste processing Facility (DWPF) high-level wastes. To support the DWPF testing, the new minimelter was scaled to the DWPF melter based on melt surface area. This new minimelter will replace an existing system and provide a platform for the research and development necessary to support the SRTC vitrification core technology mission. The second new melter is the British Nuclear Fuels, Inc., research melter system (BNFL melter), which is a scaled version of the BNFL low-activity-waste (LAW) melter proposed for vitrification of LAW at Hanford. It is designed to process a relatively large amount of actual radiative Hanford tank waste and to gather data on the composition of off-gases that will be generated by the LAW melter. Both the minimelter and BNFL melter systems consist of five primary subsystems: melter vessel, off-gas treatment, feed, power supply, and instrumentation and controls. The configuration and design of these subsystems are tailored to match the current system requirements and provide the flexibility to support future DOE vitrification programs. This paper presents a detailed discussion of the unique design challenges represented by these two new melter systems

  9. Cancer Research Center Indiana University School of Medicine

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    The Department of Energy (DOE) proposes to authorize the Indiana School of Medicine to proceed with the detailed design, construction and equipping of the proposed Cancer Research Center (CRC). A grant was executed with the University on April 21, 1992. A four-story building with basement would be constructed on the proposed site over a 24-month period. The proposed project would bring together, in one building, three existing hematology/oncology basic research programs, with improved cost-effectiveness through the sharing of common resources. The proposed site is currently covered with asphaltic pavement and is used as a campus parking lot. The surrounding area is developed campus, characterized by buildings, walkways, with minimal lawns and plantings. The proposed site has no history of prior structures and no evidence of potential sources of prior contamination of the soil. Environmental impacts of construction would be limited to minor increases in traffic, and the typical noises associated with standard building construction. The proposed CRC project operation would involve the use radionuclides and various hazardous materials in conducting clinical studies. Storage, removal and disposal of hazardous wastes would be managed under existing University programs that comply with federal and state requirements. Radiological safety programs would be governed by Nuclear Regulatory Commission (NRC) license and applicable Environmental Protection Agency (EPA) regulations. There are no other NEPA reviews currently active which are in relationship to this proposed site. The proposed project is part of a Medical Campus master plan and is consistent with applicable local zoning and land use requirements.

  10. Cancer Research Center Indiana University School of Medicine

    International Nuclear Information System (INIS)

    1994-08-01

    The Department of Energy (DOE) proposes to authorize the Indiana School of Medicine to proceed with the detailed design, construction and equipping of the proposed Cancer Research Center (CRC). A grant was executed with the University on April 21, 1992. A four-story building with basement would be constructed on the proposed site over a 24-month period. The proposed project would bring together, in one building, three existing hematology/oncology basic research programs, with improved cost-effectiveness through the sharing of common resources. The proposed site is currently covered with asphaltic pavement and is used as a campus parking lot. The surrounding area is developed campus, characterized by buildings, walkways, with minimal lawns and plantings. The proposed site has no history of prior structures and no evidence of potential sources of prior contamination of the soil. Environmental impacts of construction would be limited to minor increases in traffic, and the typical noises associated with standard building construction. The proposed CRC project operation would involve the use radionuclides and various hazardous materials in conducting clinical studies. Storage, removal and disposal of hazardous wastes would be managed under existing University programs that comply with federal and state requirements. Radiological safety programs would be governed by Nuclear Regulatory Commission (NRC) license and applicable Environmental Protection Agency (EPA) regulations. There are no other NEPA reviews currently active which are in relationship to this proposed site. The proposed project is part of a Medical Campus master plan and is consistent with applicable local zoning and land use requirements

  11. The structural biology center at the APS: an integrated user facility for macromolecular crystallography

    International Nuclear Information System (INIS)

    Rosenbaum, G.; Westbrook, E.M.

    1997-01-01

    The Structural Biology Center (SBC) has developed and operates a sector (undulator and bending magnet) of the APS as a user facility for macromolecular crystallography. Crystallographically determined structures of proteins, nucleic acids and their complexes with proteins, viruses, and complexes between macromolecules and small ligands have become of central importance in molecular and cellular biology. Major design goals were to make the extremely high brilliance of the APS available for brilliance limited studies, and to achieve a high throughput of less demanding studies, as well as optimization for MAS-phasing. Crystal samples will include extremely small crystals, crystals with large unit cells (viruses, ribosomes, etc.) and ensembles of closely similar crystal structures for drug design, protein engineering, etc. Data are recorded on a 3000x3000 pixel CCD-area detector (optionally on image plates). The x-ray optics of both beamlines has been designed to produce a highly demagnified image of the source in order to match the focal size with the sizes of the sample and the resolution element of the detector. Vertical focusing is achieved by a flat, cylindrically bent mirror. Horizontal focusing is achieved by sagitally bending the second crystal of the double crystal monochromator. Monochromatic fluxes of 1.3 * 10 13 ph/s into focal sizes of 0.08 mm (horizontal)x0.04 mm (vertical) FWHM (flux density 3.5 * 10 15 ph/s/mm 2 ) have been recorded.copyright 1997 American Institute of Physics

  12. The Art of Interpreting Epigenetic Activity | Center for Cancer Research

    Science.gov (United States)

    Even though all the cells of the human body share a common genomic blueprint, epigenetic activity such as DNA methylation, introduces molecular diversity that results in functionally and biologically different cellular constituents. In cancers, this ability of epigenetic activity to introduce molecular diversity is emerging as a powerful classifier of biological aggressiveness.

  13. Active learning and student-centered pedagogy improve student attitudes and performance in introductory biology.

    Science.gov (United States)

    Armbruster, Peter; Patel, Maya; Johnson, Erika; Weiss, Martha

    2009-01-01

    We describe the development and implementation of an instructional design that focused on bringing multiple forms of active learning and student-centered pedagogies to a one-semester, undergraduate introductory biology course for both majors and nonmajors. Our course redesign consisted of three major elements: 1) reordering the presentation of the course content in an attempt to teach specific content within the context of broad conceptual themes, 2) incorporating active and problem-based learning into every lecture, and 3) adopting strategies to create a more student-centered learning environment. Assessment of our instructional design consisted of a student survey and comparison of final exam performance across 3 years-1 year before our course redesign was implemented (2006) and during two successive years of implementation (2007 and 2008). The course restructuring led to significant improvement of self-reported student engagement and satisfaction and increased academic performance. We discuss the successes and ongoing challenges of our course restructuring and consider issues relevant to institutional change.

  14. How the confocal laser scanning microscope entered biological research.

    Science.gov (United States)

    Amos, W B; White, J G

    2003-09-01

    A history of the early development of the confocal laser scanning microscope in the MRC Laboratory of Molecular Biology in Cambridge is presented. The rapid uptake of this technology is explained by the wide use of fluorescence in the 80s. The key innovations were the scanning of the light beam over the specimen rather than vice-versa and a high magnification at the level of the detector, allowing the use of a macroscopic iris. These were followed by an achromatic all-reflective relay system, a non-confocal transmission detector and novel software for control and basic image processing. This design was commercialized successfully and has been produced and developed over 17 years, surviving challenges from alternative technologies, including solid-state scanning systems. Lessons are pointed out from the unusual nature of the original funding and research environment. Attention is drawn to the slow adoption of the instrument in diagnostic medicine, despite promising applications.

  15. U.S. Department of Energy's Bioenergy Research Centers An Overview of the Science

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-07-01

    challenges of biofuel production, DOE established three Bioenergy Research Centers (BRCs) in September 2007. Each center is pursuing the basic research underlying a range of high-risk, high-return biological solutions for bioenergy applications. Advances resulting from the BRCs are providing the knowledge needed to develop new biobased products, methods, and tools that the emerging biofuel industry can use (see sidebar, Bridging the Gap from Fundamental Biology to Industrial Innovation for Bioenergy, p. 6). The DOE BRCs have developed automated, high-throughput analysis pipelines that will accelerate scientific discovery for biology-based biofuel research. The three centers, which were selected through a scientific peer-review process, are based in geographically diverse locations - the Southeast, the Midwest, and the West Coast - with partners across the nation (see U.S. map, DOE Bioenergy Research Centers and Partners, on back cover). DOE's Lawrence Berkeley National Laboratory leads the DOE Joint BioEnergy Institute (JBEI) in California; DOE's Oak Ridge National Laboratory leads the BioEnergy Science Center (BESC) in Tennessee; and the University of Wisconsin-Madison leads the Great Lakes Bioenergy Research Center (GLBRC). Each center represents a multidisciplinary partnership with expertise spanning the physical and biological sciences, including genomics, microbial and plant biology, analytical chemistry, computational biology and bioinformatics, and engineering. Institutional partners include DOE national laboratories, universities, private companies, and nonprofit organizations.

  16. Accelerating cancer systems biology research through Semantic Web technology.

    Science.gov (United States)

    Wang, Zhihui; Sagotsky, Jonathan; Taylor, Thomas; Shironoshita, Patrick; Deisboeck, Thomas S

    2013-01-01

    Cancer systems biology is an interdisciplinary, rapidly expanding research field in which collaborations are a critical means to advance the field. Yet the prevalent database technologies often isolate data rather than making it easily accessible. The Semantic Web has the potential to help facilitate web-based collaborative cancer research by presenting data in a manner that is self-descriptive, human and machine readable, and easily sharable. We have created a semantically linked online Digital Model Repository (DMR) for storing, managing, executing, annotating, and sharing computational cancer models. Within the DMR, distributed, multidisciplinary, and inter-organizational teams can collaborate on projects, without forfeiting intellectual property. This is achieved by the introduction of a new stakeholder to the collaboration workflow, the institutional licensing officer, part of the Technology Transfer Office. Furthermore, the DMR has achieved silver level compatibility with the National Cancer Institute's caBIG, so users can interact with the DMR not only through a web browser but also through a semantically annotated and secure web service. We also discuss the technology behind the DMR leveraging the Semantic Web, ontologies, and grid computing to provide secure inter-institutional collaboration on cancer modeling projects, online grid-based execution of shared models, and the collaboration workflow protecting researchers' intellectual property. Copyright © 2012 Wiley Periodicals, Inc.

  17. Proceedings of RIKEN BNL Research Center workwhop on RHIC spin

    Energy Technology Data Exchange (ETDEWEB)

    SOFFER,J.

    1999-10-06

    This RHIC Spin Workshop is the 1999 annual meeting of the RHIC Spin Collaboration, and the second to be hosted at Brookhaven and sponsored by the RIKEN BNL Research Center. The previous meetings were at Brookhaven (1998), Marseille (1996), MIT in 1995, Argonne 1994, Tucson in 1991, and the Polarized Collider Workshop at Penn State in 1990. As noted last year, the Center provides a home for combined work on spin by theorists, experimenters, and accelerator physicists. This proceedings, as last year, is a compilation of 1 page summaries and 5 selected transparencies for each speaker. It is designed to be available soon after the workshop is completed. Speakers are welcome to include web or other references for additional material. The RHIC spin program and RHIC are rapidly becoming reality. RHIC has completed its first commissioning run, as described here by Steve Peggs. The first Siberian Snake for spin has been completed and is being installed in RHIC. A new polarized source from KEK and Triumf with over 1 milliampere of polarized H{sup minus} is being installed, described by Anatoli Zelenski. They have had a successful test of a new polarimeter for RHIC, described by Kazu Kurita and Haixin Huang. Spin commissioning is expected next spring (2000), and the first physics run for spin is anticipated for spring 2001. The purpose of the workshop is to get everyone together about once per year and discuss goals of the spin program, progress, problems, and new ideas. They also have many separate regular forums on spin. There are spin discussion sessions every Tuesday, now organized by Naohito Saito and Werner Vogelsang. The spin discussion schedule and copies of presentations are posted on http://riksg01.rhic.bnl.gov/rsc. Speakers and other spinners are encouraged to come to BNL and to lead a discussion on your favorite idea. They also have regular polarimeter and snake meetings on alternate Thursdays, led by Bill McGahern, the lead engineer for the accelerator spin

  18. Proceedings of RIKEN BNL Research Center workshop on RHIC spin

    International Nuclear Information System (INIS)

    Soffer, J.

    1999-01-01

    This RHIC Spin Workshop is the 1999 annual meeting of the RHIC Spin Collaboration, and the second to be hosted at Brookhaven and sponsored by the RIKEN BNL Research Center. The previous meetings were at Brookhaven (1998), Marseille (1996), MIT in 1995, Argonne 1994, Tucson in 1991, and the Polarized Collider Workshop at Penn State in 1990. As noted last year, the Center provides a home for combined work on spin by theorists, experimenters, and accelerator physicists. This proceedings, as last year, is a compilation of 1 page summaries and 5 selected transparencies for each speaker. It is designed to be available soon after the workshop is completed. Speakers are welcome to include web or other references for additional material. The RHIC spin program and RHIC are rapidly becoming reality. RHIC has completed its first commissioning run, as described here by Steve Peggs. The first Siberian Snake for spin has been completed and is being installed in RHIC. A new polarized source from KEK and Triumf with over 1 milliampere of polarized H minus is being installed, described by Anatoli Zelenski. They have had a successful test of a new polarimeter for RHIC, described by Kazu Kurita and Haixin Huang. Spin commissioning is expected next spring (2000), and the first physics run for spin is anticipated for spring 2001. The purpose of the workshop is to get everyone together about once per year and discuss goals of the spin program, progress, problems, and new ideas. They also have many separate regular forums on spin. There are spin discussion sessions every Tuesday, now organized by Naohito Saito and Werner Vogelsang. The spin discussion schedule and copies of presentations are posted on http://riksg01.rhic.bnl.gov/rsc. Speakers and other spinners are encouraged to come to BNL and to lead a discussion on your favorite idea. They also have regular polarimeter and snake meetings on alternate Thursdays, led by Bill McGahern, the lead engineer for the accelerator spin effort

  19. Managing environmental enhancement plans for individual research projects at a national primate research center.

    Science.gov (United States)

    Thom, Jinhee P; Crockett, Carolyn M

    2008-05-01

    We describe a method for managing environmental enhancement plans for individual research projects at a national primate research center where most monkeys are assigned to active research projects. The Psychological Well-being Program (PWB) at the University of Washington National Primate Research Center developed an Environmental Enhancement Plan form (EEPL) that allows PWB to quantify and track changes in enrichment allowances over time while ensuring that each animal is provided with as much enrichment as possible without compromising research. Very few projects involve restrictions on toys or perches. Some projects have restrictions on food treats and foraging, primarily involving the provision of these enrichments by research staff instead of husbandry staff. Restrictions are not considered exemptions unless they entirely prohibit an element of the University of Washington Environmental Enhancement Plan (UW EE Plan). All exemptions must be formally reviewed and approved by the institutional animal care and use committee. Most exemptions from elements of the UW EE Plan involve social housing. Between 2004 and 2006, the percentage of projects with no social contact restrictions increased by 1%, but those prohibiting any tactile social contact declined by 7%, and projects permitting tactile social contact during part of the study increased by 9%. The EEPL form has facilitated informing investigators about the enrichment their monkeys will receive if no restrictions or exemptions are requested and approved. The EEPL form also greatly enhances PWB's ability to coordinate the specific enrichment requirements of a project.

  20. Microgravity research in plant biological systems: Realizing the potential of molecular biology

    Science.gov (United States)

    Lewis, Norman G.; Ryan, Clarence A.

    1993-01-01

    The sole all-pervasive feature of the environment that has helped shape, through evolution, all life on Earth is gravity. The near weightlessness of the Space Station Freedom space environment allows gravitational effects to be essentially uncoupled, thus providing an unprecedented opportunity to manipulate, systematically dissect, study, and exploit the role of gravity in the growth and development of all life forms. New and exciting opportunities are now available to utilize molecular biological and biochemical approaches to study the effects of microgravity on living organisms. By careful experimentation, we can determine how gravity perception occurs, how the resulting signals are produced and transduced, and how or if tissue-specific differences in gene expression occur. Microgravity research can provide unique new approaches to further our basic understanding of development and metabolic processes of cells and organisms, and to further the application of this new knowledge for the betterment of humankind.

  1. On-going research projects at Ankara Nuclear Research Center in agriculture and animal science

    International Nuclear Information System (INIS)

    Tukenmez, I.

    2004-01-01

    The projects in progress conducted by the Center comprise nuclear-aided researches in soil fertility, plant nutrition, plant protection, improvement of field crops, improvement of horticultural plants and forest trees by mutation breeding, in vitro culture technique with mutagen treatments, use of phosphogypsum in soil amelioration, sterilization of medical supplies, wastewater treatment, animal nutrition, animal health and productivity and accreditation. The on-going main projects involving several sub-projects with the above subjects were summarized for possible future collaborations. (author)

  2. Selected Research and Development Topics on Aerospace Communications at NASA Glenn Research Center

    Science.gov (United States)

    Miranda, Felix A.; Romanofsky, Robert R.; Nessel, James A.

    2014-01-01

    This presentation discusses some of the efforts on communications RD that have been performed or are currently underway at NASA Glenn Research Center. The primary purpose of this presentation is to outline some RD topics to serve as talking points for a Technical Interchange Meeting with the Ohio State University. The meeting is scheduled to take place at The ElectroScience Laboratory of the Ohio State University on February 24, 2014.

  3. Applied Analytical Combustion/emissions Research at the NASA Lewis Research Center - a Progress Report

    Science.gov (United States)

    Deur, J. M.; Kundu, K. P.; Nguyen, H. L.

    1992-01-01

    Emissions of pollutants from future commercial transports are a significant concern. As a result, the Lewis Research Center (LeRC) is investigating various low emission combustor technologies. As part of this effort, a combustor analysis code development program was pursued to guide the combustor design process, to identify concepts having the greatest promise, and to optimize them at the lowest cost in the minimum time.

  4. Applied analytical combustion/emissions research at the NASA Lewis Research Center

    Science.gov (United States)

    Deur, J. M.; Kundu, K. P.; Nguyen, H. L.

    1992-01-01

    Emissions of pollutants from future commercial transports are a significant concern. As a result, the Lewis Research Center (LeRC) is investigating various low emission combustor technologies. As part of this effort, a combustor analysis code development program was pursued to guide the combustor design process, to identify concepts having the greatest promise, and to optimize them at the lowest cost in the minimum time.

  5. Fiscal 1982 progress report of 'comprehensive research on the management of long-lived radioactive wastes' in the Research Center for Nuclear Science and Technology, University of Tokyo

    International Nuclear Information System (INIS)

    Sekiguchi, Akira; Kosako, Toshiso

    1983-01-01

    In the Research Center for Nuclear Science and Technology, University of Tokyo, the special research project ''Comprehensive Research on the Management of Long-lived Radioactive Wastes'' is carried out in the three-year period from fiscal 1982 to 1984. The works performed in the fiscal year 1982 are described individually, each short description on research purposes and contents, results, future plans, etc. the research works in the three fields of material science, biology and process technology are buffer materials in land disposal, canisters, corrosion of waste-container materials, thermal analysis of high-level wastes, effects of tritium on cells and marine life, biological effect of long-lived nuclides, separation of tritium wastes, actinoids and krypton-iodine, environmental migration of radionuclides, and accident analysis. (Mori, K.)

  6. Scientific and technical photography at NASA Langley Research Center

    Science.gov (United States)

    Davidhazy, Andrew

    1994-01-01

    As part of my assignment connected with the Scientific and Technical Photography & Lab (STPL) at the NASA Langley Research Center I conducted a series of interviews and observed the day to day operations of the STPL with the ultimate objective of becoming exposed first hand to a scientific and technical photo/imaging department for which my school prepares its graduates. I was also asked to share my observations with the staff in order that these comments and observations might assist the STPL to better serve its customers. Meetings with several individuals responsible for various wind tunnels and with a group that provides photo-optical instrumentation services at the Center gave me an overview of the services provided by the Lab and possible areas for development. In summary form these are some of the observations that resulted from the interviews and daily contact with the STPL facility. (1) The STPL is perceived as a valuable and almost indispensable service group within the organization. This comment was invariably made by everyone. Everyone also seemed to support the idea that the STPL continue to provide its current level of service and quality. (2) The STPL generally is not perceived to be a highly technically oriented group but rather as a provider of high quality photographic illustration and documentation services. In spite of the importance and high marks assigned to the STPL there are several observations that merit consideration and evaluation for possible inclusion into the STPL's scope of expertise and future operating practices. (1) While the care and concern for artistic rendition of subjects is seen as laudable and sometimes valuable, the time that this often requires is seen as interfering with keeping the tunnels operating at maximum productivity. Tunnel managers would like to shorten down-time due to photography, have services available during evening hours and on short notice. It may be of interest to the STPL that tunnel managers are

  7. Improvements at the biological shielding of BNCT research facility in the IEA-R1 reactor

    International Nuclear Information System (INIS)

    Souza, Gregorio Soares de

    2011-01-01

    The technique of neutron capture in boron is a promising technique in cancer treatment, it uses the high LET particles from the reaction 10 B (n, α) 7 Li to destroy cancer cells.The development of this technique began in the mid-'50s and even today it is the object of study and research in various centers around the world, Brazil has built a facility that aims to conduct research in BNCT, this facility is located next to irradiation channel number three at the research nuclear reactor IEA-R1 and has a biological shielding designed to meet the radiation protection standards. This biological shielding was developed to allow them to conduct experiments with the reactor at maximum power, so it is not necessary to turn on and off the reactor to irradiate samples. However, when the channel is opened for experiments the background radiation in the experiments salon increases and this background variation makes it impossible to perform measurements in a neutron diffraction research that utilizes the irradiation channel number six. This study aims to further improve the shielding in order to minimize the variation of background making it possible to perform the research facility in BNCT without interfering with the action of the research group of the irradiation channel number six. To reach this purpose, the code MCNP5, dosimeters and activation detectors were used to plan improvements in the biological shielding. It was calculated with the help of the code an improvement that can reduce the average heat flow in 71.2% ± 13 and verified experimentally a mean reduce of 70 ± 9% in dose due to thermal neutrons. (author)

  8. Methodology implementation in order to evaluate the biological risks in the Centre for Research and Rehabilitation of Hereditary Ataxias of Cuba: a biosecurity surveillance method

    Directory of Open Access Journals (Sweden)

    Dailín Cobos Valdes

    2014-12-01

    Full Text Available Introduction: The Center for Research and Rehabilitation of Hereditary Ataxias faces biological risks. Nevertheless a Biosafety system was not yet implemented. Objective: To apply the methodology in order to evaluate these risks Materials and Methods: Interview with the researchers of the center and the use of the methodology for evaluating biological risks designed for Cobos, 2009. Results: Fifty-three biological risks were identified and evaluated, 32 as moderated, 18 as tolerable and 3 as trivial. Such classification are crucial to establish its management priorities and represent a way of surveillance in Biosafety field. Conclusion: The results of this research represent an essential factor for the Biosafety documentation development adapted to the Center and according to the legal basis in terms of biological safety in Cuba.

  9. A Survey of Knowledge Management Research & Development at NASA Ames Research Center

    Science.gov (United States)

    Keller, Richard M.; Clancy, Daniel (Technical Monitor)

    2002-01-01

    This chapter catalogs knowledge management research and development activities at NASA Ames Research Center as of April 2002. A general categorization scheme for knowledge management systems is first introduced. This categorization scheme divides knowledge management capabilities into five broad categories: knowledge capture, knowledge preservation, knowledge augmentation, knowledge dissemination, and knowledge infrastructure. Each of nearly 30 knowledge management systems developed at Ames is then classified according to this system. Finally, a capsule description of each system is presented along with information on deployment status, funding sources, contact information, and both published and internet-based references.

  10. Fiber optic transmission system delivered to Fusion Research Center of Japan Atomic Energy Research Institute

    International Nuclear Information System (INIS)

    Hayashida, Mutsuo; Hiramoto, Kiyoshi; Yamazaki, Kunihiro

    1983-01-01

    In general there are many electromagnetically induced noises in the premises of factories, power plants and substations. Under such electrically bad environments, for the computer data transmission that needs high speed processing and high reliability, the optical fiber cable is superion to the coaxial cable or the flat-type cable in aspects of the inductionlessness and a wide bandwidth. Showa Electric Wire and Cable Co., Ltd. has delivered and installed a computer data transmission system consisting of optical modems and optical fiber cables for connecting every experiment building in the premises of Fusion Research Center of Japan Atomic Energy Research Institute. This paper describes the outline of this system. (author)

  11. Successes of Small Business Innovation Research at NASA Glenn Research Center

    Science.gov (United States)

    Kim, Walter S.; Bitler, Dean W.; Prok, George M.; Metzger, Marie E.; Dreibelbis, Cindy L.; Ganss, Meghan

    2002-01-01

    This booklet of success stories highlights the NASA Glenn Research Center's accomplishments and successes by the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs. These success stories are the results of selecting projects that support NASA missions and also have high commercialization potential. Each success story describes the innovation accomplished, commercialization of the technology, and further applications and usages. This booklet emphasizes the integration and incorporation of technologies into NASA missions and other government projects. The company name and the NASA contact person are identified to encourage further usage and application of the SBIR developed technologies and also to promote further commercialization of these products.

  12. Computerized based training in nuclear safety in the nuclear research center Negev

    International Nuclear Information System (INIS)

    Ben-Shachar, B.; Krubain, H.; Sberlo, E.

    2002-01-01

    The Department of Human Resources and Training in the Nuclear Research Center, Negev, in collaboration with the Department of Radiation Protection and Safety used to organize different kinds of training and refresher courses for different aspects of safety in nuclear centers (radiation safety, biological effects of ionizing radiation, industrial safety, fire fighting, emergency procedures, etc.). All radiation workers received a training program of several days in all these subjects, each year. The administrative employees received a shorter training, each second year. The training included only frontal lectures and no quiz or exams were done. No feedback of the employees was received after the training, as well. Recently, a new training program was developed by the NRC-Negev and the CET (Center for Educational Technology), in order to perform the refresher courses. The training includes CBT-s (Computer Based Training), e.g. tutorials and quiz. The tutorial is an interactive course in one subject, including animations, video films and photo stills. The employee gets a simple and clear explanation (including pictures). After each tutorial there is a quiz which includes 7 American style questions. In the following lecture different parts from two of the tutorials used for the refresher courses, will be presented

  13. Cell Science and Cell Biology Research at MSFC: Summary

    Science.gov (United States)

    2003-01-01

    The common theme of these research programs is that they investigate regulation of gene expression in cells, and ultimately gene expression is controlled by the macromolecular interactions between regulatory proteins and DNA. The NASA Critical Path Roadmap identifies Muscle Alterations and Atrophy and Radiation Effects as Very Serious Risks and Severe Risks, respectively, in long term space flights. The specific problem addressed by Dr. Young's research ("Skeletal Muscle Atrophy and Muscle Cell Signaling") is that skeletal muscle loss in space cannot be prevented by vigorous exercise. Aerobic skeletal muscles (i.e., red muscles) undergo the most extensive atrophy during long-term space flight. Of the many different potential avenues for preventing muscle atrophy, Dr. Young has chosen to study the beta-adrenergic receptor (betaAR) pathway. The reason for this choice is that a family of compounds called betaAR agonists will preferentially cause an increase in muscle mass of aerobic muscles (i.e., red muscle) in animals, potentially providing a specific pharmacological solution to muscle loss in microgravity. In addition, muscle atrophy is a widespread medical problem in neuromuscular diseases, spinal cord injury, lack of exercise, aging, and any disease requiring prolonged bedridden status. Skeletal muscle cells in cell culture are utilized as a model system to study this problem. Dr. Richmond's research ("Radiation & Cancer Biology of Mammary Cells in Culture") is directed toward developing a laboratory model for use in risk assessment of cancer caused by space radiation. This research is unique because a human model will be developed utilizing human mammary cells that are highly susceptible to tumor development. This approach is preferential over using animal cells because of problems in comparing radiation-induced cancers between humans and animals.

  14. The Implementation of Research-based Learning on Biology Seminar Course in Biology Education Study Program of FKIP UMRAH

    Science.gov (United States)

    Amelia, T.

    2018-04-01

    Biology Seminar is a course in Biology Education Study Program of Faculty of Teacher Training and Education University of Maritim Raja Ali Haji (FKIP UMRAH) that requires students to have the ability to apply scientific attitudes, perform scientific writing and undertake scientific publications on a small scale. One of the learning strategies that can drive the achievement of learning outcomes in this course is Research-Based Learning. Research-Based Learning principles are considered in accordance with learning outcomes in Biology Seminar courses and generally in accordance with the purpose of higher education. On this basis, this article which is derived from a qualitative research aims at describing Research-based Learning on Biology Seminar course. Based on a case study research, it was known that Research-Based Learning on Biology Seminar courses is applied through: designing learning activities around contemporary research issues; teaching research methods, techniques and skills explicitly within program; drawing on personal research in designing and teaching courses; building small-scale research activities into undergraduate assignment; and infusing teaching with the values of researchers.

  15. Centro de Biologia Molecular "Severo Ochoa": a center for basic research into Alzheimer's disease.

    Science.gov (United States)

    Avila, Jesus; Hernandez, Felix; Wandosell, Francisco; Lucas, Jose J; Esteban, Jose A; Ledesma, M Dolores; Bullido, Maria J

    2010-01-01

    One important aspect of studies carried out at the Center for Molecular Biology "Severo Ochoa" is focused on basic aspects of Alzheimer's disease, mainly the search for suitable therapeutic targets for this disorder. Several groups at the Center are involved in these studies, and, in this spotlight, the work they are carrying out will be described.

  16. Small Radioisotope Power System Testing at NASA Glenn Research Center

    Science.gov (United States)

    Dugala, Gina; Bell, Mark; Oriti, Salvatore; Fraeman, Martin; Frankford, David; Duven, Dennis

    2013-01-01

    In April 2009, NASA Glenn Research Center (GRC) formed an integrated product team (IPT) to develop a Small Radioisotope Power System (SRPS) utilizing a single Advanced Stirling Convertor (ASC) with passive balancer. A single ASC produces approximately 80 We making this system advantageous for small distributed lunar science stations. The IPT consists of Sunpower, Inc., to provide the single ASC with a passive balancer, The Johns Hopkins University Applied Physics Laboratory (JHUAPL) to design an engineering model Single Convertor Controller (SCC) for an ASC with a passive balancer, and NASA GRC to provide technical support to these tasks and to develop a simulated lunar lander test stand. The single ASC with a passive balancer, simulated lunar lander test stand, and SCC were delivered to GRC and were tested as a system. The testing sequence at GRC included SCC fault tolerance, integration, electromagnetic interference (EMI), vibration, and extended operation testing. The SCC fault tolerance test characterized the SCCs ability to handle various fault conditions, including high or low bus power consumption, total open load or short circuit, and replacing a failed SCC card while the backup maintains control of the ASC. The integrated test characterized the behavior of the system across a range of operating conditions, including variations in cold-end temperature and piston amplitude, including the emitted vibration to both the sensors on the lunar lander and the lunar surface. The EMI test characterized the AC and DC magnetic and electric fields emitted by the SCC and single ASC. The vibration test confirms the SCCs ability to control the single ASC during launch. The extended operation test allows data to be collected over a period of thousands of hours to obtain long term performance data of the ASC with a passive balancer and the SCC. This paper will discuss the results of each of these tests.

  17. HEASARC - The High Energy Astrophysics Science Archive Research Center

    Science.gov (United States)

    Smale, Alan P.

    2011-01-01

    The High Energy Astrophysics Science Archive Research Center (HEASARC) is NASA's archive for high-energy astrophysics and cosmic microwave background (CMB) data, supporting the broad science goals of NASA's Physics of the Cosmos theme. It provides vital scientific infrastructure to the community by standardizing science data formats and analysis programs, providing open access to NASA resources, and implementing powerful archive interfaces. Over the next five years the HEASARC will ingest observations from up to 12 operating missions, while serving data from these and over 30 archival missions to the community. The HEASARC archive presently contains over 37 TB of data, and will contain over 60 TB by the end of 2014. The HEASARC continues to secure major cost savings for NASA missions, providing a reusable mission-independent framework for reducing, analyzing, and archiving data. This approach was recognized in the NRC Portals to the Universe report (2007) as one of the HEASARC's great strengths. This poster describes the past and current activities of the HEASARC and our anticipated developments in coming years. These include preparations to support upcoming high energy missions (NuSTAR, Astro-H, GEMS) and ground-based and sub-orbital CMB experiments, as well as continued support of missions currently operating (Chandra, Fermi, RXTE, Suzaku, Swift, XMM-Newton and INTEGRAL). In 2012 the HEASARC (which now includes LAMBDA) will support the final nine-year WMAP data release. The HEASARC is also upgrading its archive querying and retrieval software with the new Xamin system in early release - and building on opportunities afforded by the growth of the Virtual Observatory and recent developments in virtual environments and cloud computing.

  18. The Begun Center for Violence Prevention Research and Education at Case Western Reserve University

    Science.gov (United States)

    Flannery, Daniel J.; Singer, Mark I.

    2015-01-01

    Established in the year 2000, the Begun Center for Violence Prevention Research and Education is a multidisciplinary center located at a school of social work that engages in collaborative, community-based research and evaluation that spans multiple systems and disciplines. The Center currently occupies 4,200 sq. ft. with multiple offices and…

  19. Refractory Research Group - U.S. DOE, Albany Research Center [Institution Profile

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, James P.

    2004-09-01

    The refractory research group at the Albany Research Center (ARC) has a long history of conducting materials research within the U.S. Bureau of Mines, and more recently, within the U.S. Dept. of Energy. When under the U.S. Bureau of Mines, research was driven by national needs to develop substitute materials and to conserve raw materials. This mission was accomplished by improving refractory material properties and/or by recycling refractories using critical and strategic materials. Currently, as a U.S. Dept of Energy Fossil Energy field site, research is driven primarily by the need to assist DOE in meeting its vision to develop economically and environmentally viable technologies for the production of electricity from fossil fuels. Research at ARC impacts this vision by: • Providing information on the performance characteristics of materials being specified for the current generation of power systems; • Developing cost-effective, high performance materials for inclusion in the next generation of fossil power systems; and • Solving environmental emission and waste problems related to fossil energy systems. A brief history of past refractory research within the U.S. Bureau of Mines, the current refractory research at ARC, and the equipment and capabilities used to conduct refractory research at ARC will be discussed.

  20. Aircraft Engine Noise Research and Testing at the NASA Glenn Research Center

    Science.gov (United States)

    Elliott, Dave

    2015-01-01

    The presentation will begin with a brief introduction to the NASA Glenn Research Center as well as an overview of how aircraft engine noise research fits within the organization. Some of the NASA programs and projects with noise content will be covered along with the associated goals of aircraft noise reduction. Topics covered within the noise research being presented will include noise prediction versus experimental results, along with engine fan, jet, and core noise. Details of the acoustic research conducted at NASA Glenn will include the test facilities available, recent test hardware, and data acquisition and analysis methods. Lastly some of the actual noise reduction methods investigated along with their results will be shown.

  1. Teams and teamwork at NASA Langley Research Center

    Science.gov (United States)

    Dickinson, Terry L.

    1994-01-01

    The recent reorganization and shift to managing total quality at the NASA Langley Research Center (LaRC) has placed an increasing emphasis on teams and teamwork in accomplishing day-to-day work activities and long-term projects. The purpose of this research was to review the nature of teams and teamwork at LaRC. Models of team performance and teamwork guided the gathering of information. Current and former team members served as participants; their collective experience reflected membership in over 200 teams at LaRC. The participants responded to a survey of open-ended questions which assessed various aspects of teams and teamwork. The participants also met in a workshop to clarify and elaborate on their responses. The work accomplished by the teams ranged from high-level managerial decision making (e.g., developing plans for LaRC reorganization) to creating scientific proposals (e.g., describing spaceflight projects to be designed, sold, and built). Teams typically had nine members who remained together for six months. Member turnover was around 20 percent; this turnover was attributed to heavy loads of other work assignments and little formal recognition and reward for team membership. Team members usually shared a common and valued goal, but there was not a clear standard (except delivery of a document) for knowing when the goal was achieved. However, members viewed their teams as successful. A major factor in team success was the setting of explicit a priori rules for communication. Task interdependencies between members were not complex (e.g., sharing of meeting notes and ideas about issues), except between members of scientific teams (i.e., reliance on the expertise of others). Thus, coordination of activities usually involved scheduling and attendance of team meetings. The team leader was designated by the team's sponsor. This leader usually shared power and responsibilities with other members, such that team members established their own operating

  2. Soil protists: a fertile frontier in soil biology research.

    Science.gov (United States)

    Geisen, Stefan; Mitchell, Edward A D; Adl, Sina; Bonkowski, Michael; Dunthorn, Micah; Ekelund, Flemming; Fernández, Leonardo D; Jousset, Alexandre; Krashevska, Valentyna; Singer, David; Spiegel, Frederick W; Walochnik, Julia; Lara, Enrique

    2018-05-01

    Protists include all eukaryotes except plants, fungi and animals. They are an essential, yet often forgotten, component of the soil microbiome. Method developments have now furthered our understanding of the real taxonomic and functional diversity of soil protists. They occupy key roles in microbial foodwebs as consumers of bacteria, fungi and other small eukaryotes. As parasites of plants, animals and even of larger protists, they regulate populations and shape communities. Pathogenic forms play a major role in public health issues as human parasites, or act as agricultural pests. Predatory soil protists release nutrients enhancing plant growth. Soil protists are of key importance for our understanding of eukaryotic evolution and microbial biogeography. Soil protists are also useful in applied research as bioindicators of soil quality, as models in ecotoxicology and as potential biofertilizers and biocontrol agents. In this review, we provide an overview of the enormous morphological, taxonomical and functional diversity of soil protists, and discuss current challenges and opportunities in soil protistology. Research in soil biology would clearly benefit from incorporating more protistology alongside the study of bacteria, fungi and animals.

  3. Roles of radiation chemistry in development and research of radiation biology

    International Nuclear Information System (INIS)

    Min Rui

    2009-01-01

    Radiation chemistry acts as a bridge connecting radiation physics with radiation biology in spatial and temporal insight. The theory, model, and methodology coming from radiation chemistry play an important role in the research and development of radiation biology. The chemical changes induced by ionizing radiation are involved not only in early event of biological effects caused by ionizing radiation but in function radiation biology, such as DNA damage and repair, sensitive modification, metabolism and function of active oxygen and so on. Following the research development of radiation biology, systems radiation biology, accurate quality and quantity of radiation biology effects need more methods and perfect tools from radiation chemistry. (authors)

  4. Program budget 1992 of the Karlsruhe Nuclear Research Center. As of November 19, 1991

    International Nuclear Information System (INIS)

    1992-01-01

    In the future, the research program of the Nuclear Research Center in Karlsruhe will concentrate on three areas, which are of the same status over the medium term: Environmental research, energy research and micro system technology and fundamental research. The central infrastructure, the financial planning and the assignment of research and development projects of the Nuclear Research Center are presented in tables. (orig./HP) [de

  5. TRANSPORTATION RESEARCH CONTRIBUTIONS TO SOCIETY BY UNIVERSITY TRANSPORTATION CENTERS

    Directory of Open Access Journals (Sweden)

    Robert C. JOHNS

    2003-01-01

    Full Text Available This paper discusses the importance of knowledge in the global economy and reviews the process in which knowledge is applied to develop innovations. It confirms the importance of innovation as a key factor for success in today's competitive environment. The paper discusses the contributions a university can make to the innovation process in the field of transportation, and offers a vision of how a university center can enhance and facilitate these contributions. It then describes the efforts of one center, including three examples of innovations facilitated by the center in traffic detection, regional planning, and pavement management. The paper concludes with suggestions that would strengthen the societal contributions of university transportation centers.

  6. Using biological control research in the classroom to promote scientific inquiry and literacy

    Science.gov (United States)

    Many scientists who research biological control also teach at universities or more informally through cooperative outreach. The purpose of this paper is to review biological control activities for the classroom in four refereed journals, The American Biology Teacher, Journal of Biological Education...

  7. 76 FR 64355 - Science Advisory Board to the National Center for Toxicological Research; Notice of Meeting

    Science.gov (United States)

    2011-10-18

    ... Microbiology and the Division of Personalized Nutrition and Medicine will update the SAB on the major research... of the findings on the public health. The Center representatives from the Center for Veterinary...

  8. New national Biobank of The Danish Center for Strategic Research on Type 2 Diabetes (DD2)

    DEFF Research Database (Denmark)

    Christensen, Henry; Nielsen, Jens Steen; Sørensen, Karina Meden

    2012-01-01

    Long-term storage of biological samples from patients has become increasingly important in studies of disease control and treatment. The first nationwide Danish diabetes project, ie, The Danish Center for Strategic Research in Type II Diabetes (DD2), aims to improve treatment and the long......-term outcome of patients with newly diagnosed type 2 diabetes (T2D). The DD2 project includes establishment of a biobank with samples from 50,000 patients with newly diagnosed T2D. This paper describes how blood and urine samples from 10,000 patients per year are collected, handled, and stored. The biobank...... includes whole blood, DNA, and plasma and urine samples, all frozen at -80°C. Sampling tubes have been standardized and are sent to hospital outpatient clinics and general practitioners where samples are taken, handled, aliquoted, and returned by mail overnight in standardized cryostorage tubes. When...

  9. Institutional profile: integrated center for research and treatment of vertigo, balance and ocular motor disorders.

    Science.gov (United States)

    Brandt, Thomas; Zwergal, Andreas; Jahn, Klaus; Strupp, Michael

    2010-01-01

    transversal network at one site for the management of patients. This should professionalize both the management and the international recruitment of patients (integrated care, telemedicine); to organize the study infrastructure for prospective multicenter clinical studies as well as to free clinical scientists from administrative tasks; to promote translational research with a focus on the innovative topics of molecular, functional and structural imaging, experimental and clinical pharmacotherapy, clinical research of vertigo and balance disorders, mathematical modelling, interaction between biological and technical systems (robotics), and research on functionality and the quality of life; to offer new attractive educational paths and career images for medical doctors, students of the natural sciences, and engineers in clinical research in order to overcome traditional hierarchical structures. This should promote the principles of efficiency and self-reliance; to supplement the existing excellence with up to eight groups of young scientists and up to eight professorships (tenure track). This should also be seen as an incentive that will attract the best young scientists; to incorporate (IFB(LMU)) competence into the existing medical and biological graduate schools. The (IFB(LMU)) is a unique center - worldwide.

  10. 48 CFR 1335.017 - Federal funded research and development centers.

    Science.gov (United States)

    2010-10-01

    ... OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1335.017 Federal funded research and development centers. ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Federal funded research...

  11. Progress report of Cekmece Nuclear Research and Training Center for 1981

    International Nuclear Information System (INIS)

    1982-01-01

    Presented are the research works carried out in 1981 in Energy, Radiological Safety, Radioisotope, Application of Nuclear Techniques and Basic Research of Cekmece Nuclear Research and Training Center. (author)

  12. Modeling and Analysis of Multidiscipline Research Teams at NASA Langley Research Center: A Systems Thinking Approach

    Science.gov (United States)

    Waszak, Martin R.; Barthelemy, Jean-Francois; Jones, Kenneth M.; Silcox, Richard J.; Silva, Walter A.; Nowaczyk, Ronald H.

    1998-01-01

    Multidisciplinary analysis and design is inherently a team activity due to the variety of required expertise and knowledge. As a team activity, multidisciplinary research cannot escape the issues that affect all teams. The level of technical diversity required to perform multidisciplinary analysis and design makes the teaming aspects even more important. A study was conducted at the NASA Langley Research Center to develop a model of multidiscipline teams that can be used to help understand their dynamics and identify key factors that influence their effectiveness. The study sought to apply the elements of systems thinking to better understand the factors, both generic and Langley-specific, that influence the effectiveness of multidiscipline teams. The model of multidiscipline research teams developed during this study has been valuable in identifying means to enhance team effectiveness, recognize and avoid problem behaviors, and provide guidance for forming and coordinating multidiscipline teams.

  13. Overview of Dynamics Integration Research (DIR) program at Langley Research Center

    Science.gov (United States)

    Sliwa, Steven M.; Abel, Irving

    1989-01-01

    Research goals and objectives for an ongoing activity at Langley Research Center (LaRC) are described. The activity is aimed principally at dynamics optimization for aircraft. The effort involves active participation by the Flight Systems, Structures, and Electronics directorates at LaRC. The Functional Integration Technology (FIT) team has been pursuing related goals since 1985. A prime goal has been the integration and optimization of vehicle dynamics through collaboration at the basic principles or equation level. Some significant technical progress has been accomplished since then and is reflected here. An augmentation for this activity, Dynamics Integration Research (DIR), has been proposed to NASA Headquarters and is being considered for funding in FY 1990 or FY 1991.

  14. Primary Care Research in the Patient-Centered Outcomes Research Institute's Portfolio.

    Science.gov (United States)

    Selby, Joe V; Slutsky, Jean R

    2016-04-01

    In their article in this issue, Mazur and colleagues analyze the characteristics of early recipients of funding from the Patient-Centered Outcomes Research Institute (PCORI). Mazur and colleagues note correctly that PCORI has a unique purpose and mission and suggest that it should therefore have a distinct portfolio of researchers and departments when compared with other funders such as the National Institutes of Health (NIH). Responding on behalf of PCORI, the authors of this Commentary agree with the characterization of PCORI's mission as distinct from that of NIH and others. They agree too that data found on PCORI's Web site demonstrate that PCORI's portfolio of researchers and departments is more diverse and more heavily populated with clinician researchers, as would be expected. The authors take issue with Mazur and colleagues' suggestion that because half of clinical visits occur within primary care settings, half of PCORI's funded research should be based in primary care departments. PCORI's portfolio reflects what patients and others tell PCORI are the critical questions. Many of these do, in fact, occur with more complex conditions in specialty care. The authors question whether the research of primary care departments is too narrowly focused and whether it sufficiently considers study of these complex conditions. Research on more complex conditions including heart failure, coronary artery disease, and multiple comorbid conditions could be highly valuable when approached from the primary care perspective, where many of the comparative effectiveness questions first arise.

  15. Using Biological-Control Research in the Classroom to Promote Scientific Inquiry & Literacy

    Science.gov (United States)

    Richardson, Matthew L.; Richardson, Scott L.; Hall, David G.

    2012-01-01

    Scientists researching biological control should engage in education because translating research programs into classroom activities is a pathway to increase scientific literacy among students. Classroom activities focused on biological control target all levels of biological organization and can be cross-disciplinary by drawing from subject areas…

  16. Implications of Plasmodium vivax Biology for Control, Elimination, and Research

    Science.gov (United States)

    Olliaro, Piero L.; Barnwell, John W.; Barry, Alyssa; Mendis, Kamini; Mueller, Ivo; Reeder, John C.; Shanks, G. Dennis; Snounou, Georges; Wongsrichanalai, Chansuda

    2016-01-01

    This paper summarizes our current understanding of the biology of Plasmodium vivax, how it differs from Plasmodium falciparum, and how these differences explain the need for P. vivax-tailored interventions. The article further pinpoints knowledge gaps where investments in research are needed to help identify and develop such specific interventions. The principal obstacles to reduce and eventually eliminate P. vivax reside in 1) its higher vectorial capacity compared with P. falciparum due to its ability to develop at lower temperature and over a shorter sporogonic cycle in the vector, allowing transmission in temperate zones and making it less sensitive to vector control measures that are otherwise effective on P. falciparum; 2) the presence of dormant liver forms (hypnozoites), sustaining multiple relapsing episodes from a single infectious bite that cannot be diagnosed and are not susceptible to any available antimalarial except primaquine, with routine deployment restricted by toxicity; 3) low parasite densities, which are difficult to detect with current diagnostics leading to missed diagnoses and delayed treatments (and protracted transmission), coupled with 4) transmission stages (gametocytes) occurring early in acute infections, before infection is diagnosed. PMID:27799636

  17. Dynamic models in research and management of biological invasions.

    Science.gov (United States)

    Buchadas, Ana; Vaz, Ana Sofia; Honrado, João P; Alagador, Diogo; Bastos, Rita; Cabral, João A; Santos, Mário; Vicente, Joana R

    2017-07-01

    Invasive species are increasing in number, extent and impact worldwide. Effective invasion management has thus become a core socio-ecological challenge. To tackle this challenge, integrating spatial-temporal dynamics of invasion processes with modelling approaches is a promising approach. The inclusion of dynamic processes in such modelling frameworks (i.e. dynamic or hybrid models, here defined as models that integrate both dynamic and static approaches) adds an explicit temporal dimension to the study and management of invasions, enabling the prediction of invasions and optimisation of multi-scale management and governance. However, the extent to which dynamic approaches have been used for that purpose is under-investigated. Based on a literature review, we examined the extent to which dynamic modelling has been used to address invasions worldwide. We then evaluated how the use of dynamic modelling has evolved through time in the scope of invasive species management. The results suggest that modelling, in particular dynamic modelling, has been increasingly applied to biological invasions, especially to support management decisions at local scales. Also, the combination of dynamic and static modelling approaches (hybrid models with a spatially explicit output) can be especially effective, not only to support management at early invasion stages (from prevention to early detection), but also to improve the monitoring of invasion processes and impact assessment. Further development and testing of such hybrid models may well be regarded as a priority for future research aiming to improve the management of invasions across scales. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. BRIC-100VC Biological Research in Canisters (BRIC)-100VC

    Science.gov (United States)

    Richards, Stephanie E.; Levine, Howard G. (Compiler); Romero, Vergel

    2016-01-01

    The Biological Research in Canisters (BRIC) is an anodized-aluminum cylinder used to provide passive stowage for investigations of the effects of space flight on small specimens. The BRIC 100 mm petri dish vacuum containment unit (BRIC-100VC) has supported Dugesia japonica (flatworm) within spring under normal atmospheric conditions for 29 days in space and Hemerocallis lilioasphodelus L. (daylily) somatic embryo development within a 5% CO2 gaseous environment for 4.5 months in space. BRIC-100VC is a completely sealed, anodized-aluminum cylinder (Fig. 1) providing containment and structural support of the experimental specimens. The top and bottom lids of the canister include rapid disconnect valves for filling the canister with selected gases. These specialized valves allow for specific atmospheric containment within the canister, providing a gaseous environment defined by the investigator. Additionally, the top lid has been designed with a toggle latch and O-ring assembly allowing for prompt sealing and removal of the lid. The outside dimensions of the BRIC-100VC canisters are 16.0 cm (height) x 11.4 cm (outside diameter). The lower portion of the canister has been equipped with sufficient storage space for passive temperature and relative humidity data loggers. The BRIC- 100VC canister has been optimized to accommodate standard 100 mm laboratory petri dishes or 50 mL conical tubes. Depending on storage orientation, up to 6 or 9 canisters have been flown within an International Space Station (ISS) stowage locker.

  19. Implications of Plasmodium vivax Biology for Control, Elimination, and Research.

    Science.gov (United States)

    Olliaro, Piero L; Barnwell, John W; Barry, Alyssa; Mendis, Kamini; Mueller, Ivo; Reeder, John C; Shanks, G Dennis; Snounou, Georges; Wongsrichanalai, Chansuda

    2016-12-28

    This paper summarizes our current understanding of the biology of Plasmodium vivax, how it differs from Plasmodium falciparum, and how these differences explain the need for P. vivax-tailored interventions. The article further pinpoints knowledge gaps where investments in research are needed to help identify and develop such specific interventions. The principal obstacles to reduce and eventually eliminate P. vivax reside in 1) its higher vectorial capacity compared with P. falciparum due to its ability to develop at lower temperature and over a shorter sporogonic cycle in the vector, allowing transmission in temperate zones and making it less sensitive to vector control measures that are otherwise effective on P. falciparum; 2) the presence of dormant liver forms (hypnozoites), sustaining multiple relapsing episodes from a single infectious bite that cannot be diagnosed and are not susceptible to any available antimalarial except primaquine, with routine deployment restricted by toxicity; 3) low parasite densities, which are difficult to detect with current diagnostics leading to missed diagnoses and delayed treatments (and protracted transmission), coupled with 4) transmission stages (gametocytes) occurring early in acute infections, before infection is diagnosed. © The American Society of Tropical Medicine and Hygiene.

  20. High power electromagnetic propulsion research at the NASA Glenn Research Center

    International Nuclear Information System (INIS)

    LaPointe, Michael R.; Sankovic, John M.

    2000-01-01

    Interest in megawatt-class electromagnetic propulsion has been rekindled to support newly proposed high power orbit transfer and deep space mission applications. Electromagnetic thrusters can effectively process megawatts of power to provide a range of specific impulse values to meet diverse in-space propulsion requirements. Potential applications include orbit raising for the proposed multi-megawatt Space Solar Power Satellite and other large commercial and military space platforms, lunar and interplanetary cargo missions in support of the NASA Human Exploration and Development of Space strategic enterprise, robotic deep space exploration missions, and near-term interstellar precursor missions. As NASA's lead center for electric propulsion, the Glenn Research Center is developing a number of high power electromagnetic propulsion technologies to support these future mission applications. Program activities include research on MW-class magnetoplasmadynamic thrusters, high power pulsed inductive thrusters, and innovative electrodeless plasma thruster concepts. Program goals are highlighted, the status of each research area is discussed, and plans are outlined for the continued development of efficient, robust high power electromagnetic thrusters