Fluid dynamics in biological active nematics
Tan, Amanda; Hirst, Linda
We use biological materials to form a self-mixing active system that consists of microtubules driven by kinesin clusters. Microtubules are rigid biopolymers that are a part of the cytoskeleton. Kinesin motors are molecular motors that walk along microtubules to transport cellular cargo. In this system, microtubules are bundled together, and as the kinesin clusters walk along the filaments, the microtubule bundles move relative to each other. As microtubules shear against each other, they extend, bend, buckle and fracture. When confined in a 2D water-oil interface, the system becomes an active nematic that self-mixes due to the buckling and fracturing. To quantify this self-mixing, we attached beads to the microtubules, and tracked their motion. We quantify the quality of mixing using the bead trajectories. This new active material has potential applications as a self-mixing solvent. CCBM NSF-CREST, UC Merced Health Science Research Institute.
DEFF Research Database (Denmark)
Brorsen, Michael
These lecture notes are intended mainly for the 7th semester course "Fluid Dynamics" offered by the Study Committee on Civil Engineering, Aalborg University.......These lecture notes are intended mainly for the 7th semester course "Fluid Dynamics" offered by the Study Committee on Civil Engineering, Aalborg University....
Integrating fluid dynamic and biologic effects on staphylococci bacteria biofilms
Sherman, Erica; Endres, Jennifer; Bayles, Kenneth; Wei, Timothy
2017-11-01
Staphylococcus aureus bacteria are able to form biofilms and distinctive tower structures that facilitate their ability to tolerate treatment and to spread within the human body. The formation of towers, which break off, get carried downstream and serve to initiate biofilms in other parts of the body are of particular interest here. In previous work on biofilm growth and evolution in steady, laminar microchannel flows, it has been established that tower formation occurs around a very limited range of applied shear stresses centered on 0.6 dynes/cm2. Quantifying cell density characteristics as a function of time during biofilm formation reveals indicators of tower development hours before towers actually form and become visible. The next step in this research is to explore biological factors that might explain why this specific shear is so important. Additional studies with mutants, e.g. ica-A, that have been tied to tower formation have been conducted. The shear dependence of these mutants and their correlation to the behavior of wild type S. aureus is examined.
Ruban, Anatoly I
This is the first book in a four-part series designed to give a comprehensive and coherent description of Fluid Dynamics, starting with chapters on classical theory suitable for an introductory undergraduate lecture course, and then progressing through more advanced material up to the level of modern research in the field. The present Part 1 consists of four chapters. Chapter 1 begins with a discussion of Continuum Hypothesis, which is followed by an introduction to macroscopic functions, the velocity vector, pressure, density, and enthalpy. We then analyse the forces acting inside a fluid, and deduce the Navier-Stokes equations for incompressible and compressible fluids in Cartesian and curvilinear coordinates. In Chapter 2 we study the properties of a number of flows that are presented by the so-called exact solutions of the Navier-Stokes equations, including the Couette flow between two parallel plates, Hagen-Poiseuille flow through a pipe, and Karman flow above an infinite rotating disk. Chapter 3 is d...
Fluid dynamics of dilatant fluid
DEFF Research Database (Denmark)
Nakanishi, Hiizu; Nagahiro, Shin-ichiro; Mitarai, Namiko
2012-01-01
A dense mixture of granules and liquid often shows a severe shear thickening and is called a dilatant fluid. We construct a fluid dynamics model for the dilatant fluid by introducing a phenomenological state variable for a local state of dispersed particles. With simple assumptions for an equation...
Cerbino, Roberto; Cicuta, Pietro
2017-09-01
Differential dynamic microscopy (DDM) is a technique that exploits optical microscopy to obtain local, multi-scale quantitative information about dynamic samples, in most cases without user intervention. It is proving extremely useful in understanding dynamics in liquid suspensions, soft materials, cells, and tissues. In DDM, image sequences are analyzed via a combination of image differences and spatial Fourier transforms to obtain information equivalent to that obtained by means of light scattering techniques. Compared to light scattering, DDM offers obvious advantages, principally (a) simplicity of the setup; (b) possibility of removing static contributions along the optical path; (c) power of simultaneous different microscopy contrast mechanisms; and (d) flexibility of choosing an analysis region, analogous to a scattering volume. For many questions, DDM has also advantages compared to segmentation/tracking approaches and to correlation techniques like particle image velocimetry. The very straightforward DDM approach, originally demonstrated with bright field microscopy of aqueous colloids, has lately been used to probe a variety of other complex fluids and biological systems with many different imaging methods, including dark-field, differential interference contrast, wide-field, light-sheet, and confocal microscopy. The number of adopting groups is rapidly increasing and so are the applications. Here, we briefly recall the working principles of DDM, we highlight its advantages and limitations, we outline recent experimental breakthroughs, and we provide a perspective on future challenges and directions. DDM can become a standard primary tool in every laboratory equipped with a microscope, at the very least as a first bias-free automated evaluation of the dynamics in a system.
Fluid dynamic transient analysis
International Nuclear Information System (INIS)
Vilhena Reigosa, R. de
1992-01-01
This paper describes the methodology adopted at NUCLEN for the fluid dynamic analyses for ANGRA 2. The fluid dynamic analysis allows, through computer codes to simulate and quantify the loads resulting from fluid dynamic transients caused by postulated ruptures or operational transients, in the piping of the safety systems and of the important operational systems. (author)
International Nuclear Information System (INIS)
Myeong, Hyeon Guk
1999-06-01
This book deals with computational fluid dynamics with basic and history of numerical fluid dynamics, introduction of finite volume method using one-dimensional heat conduction equation, solution of two-dimensional heat conduction equation, solution of Navier-Stokes equation, fluid with heat transport, turbulent flow and turbulent model, Navier-Stokes solution by generalized coordinate system such as coordinate conversion, conversion of basic equation, program and example of calculation, application of abnormal problem and high speed solution of numerical fluid dynamics.
Energy Technology Data Exchange (ETDEWEB)
Garrison, Laura A. [Voith Siemens Hydro Power Generation, Inc., York, PA (United States); Fisher, Jr., Richard K. [Voith Siemens Hydro Power Generation, Inc., York, PA (United States); Sale, Michael J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Cada, Glenn [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
2002-07-01
One of the contributing factors to fish injury in a turbine environment is shear stress. This paper presents the use of computational fluid dynamics (CFD) to display and quantify areas of elevated shear stress in the Wanapum Kaplan turbine operating at four different flow conditions over its operating range. CFD observations will be compared to field test observations at the same four flow conditions. Methods developed here could be used to facilitate the design of turbines and related water passages with lower risks of fish injury.
Microgravity Fluids for Biology, Workshop
Griffin, DeVon; Kohl, Fred; Massa, Gioia D.; Motil, Brian; Parsons-Wingerter, Patricia; Quincy, Charles; Sato, Kevin; Singh, Bhim; Smith, Jeffrey D.; Wheeler, Raymond M.
2013-01-01
Microgravity Fluids for Biology represents an intersection of biology and fluid physics that present exciting research challenges to the Space Life and Physical Sciences Division. Solving and managing the transport processes and fluid mechanics in physiological and biological systems and processes are essential for future space exploration and colonization of space by humans. Adequate understanding of the underlying fluid physics and transport mechanisms will provide new, necessary insights and technologies for analyzing and designing biological systems critical to NASAs mission. To enable this mission, the fluid physics discipline needs to work to enhance the understanding of the influence of gravity on the scales and types of fluids (i.e., non-Newtonian) important to biology and life sciences. In turn, biomimetic, bio-inspired and synthetic biology applications based on physiology and biology can enrich the fluid mechanics and transport phenomena capabilities of the microgravity fluid physics community.
Fiszdon, W
1965-01-01
Fluid Dynamics Transactions, Volume 2 compiles 46 papers on fluid dynamics, a subdiscipline of fluid mechanics that deals with fluid flow. The topics discussed in this book include developments in interference theory for aeronautical applications; diffusion from sources in a turbulent boundary layer; unsteady motion of a finite wing span in a compressible medium; and wall pressure covariance and comparison with experiment. The certain classes of non-stationary axially symmetric flows in magneto-gas-dynamics; description of the phenomenon of secondary flows in curved channels by means of co
Shivamoggi, Bhimsen K
1998-01-01
"Although there are many texts and monographs on fluid dynamics, I do not know of any which is as comprehensive as the present book. It surveys nearly the entire field of classical fluid dynamics in an advanced, compact, and clear manner, and discusses the various conceptual and analytical models of fluid flow." - Foundations of Physics on the first edition. Theoretical Fluid Dynamics functions equally well as a graduate-level text and a professional reference. Steering a middle course between the empiricism of engineering and the abstractions of pure mathematics, the author focuses
Applications of fluid dynamics
International Nuclear Information System (INIS)
Round, G.R.; Garg, V.K.
1986-01-01
This book describes flexible and practical approach to learning the basics of fluid dynamics. Each chapter is a self-contained work session and includes a fluid dynamics concept, an explanation of the principles involved, an illustration of their application and references on where more detailed discussions can be found
Bird, R. Byron
1980-01-01
Problems in polymer fluid dynamics are described, including development of constitutive equations, rheometry, kinetic theory, flow visualization, heat transfer studies, flows with phase change, two-phase flow, polymer unit operations, and drag reduction. (JN)
Videotapes and Movies on Fluid Dynamics and Fluid Machines
Carr, Bobbie; Young, Virginia E.
1996-01-01
Chapter 17 of Handbook of Fluid Dynamics and Fluid Machinery: Experimental and Computational Fluid Dynamics, Volume 11. A list of videorecordings and 16mm motion pictures about Fluid Dynamics and Fluid Machines.
Ryu, Sangjin; Matsudaira, Paul
2008-11-01
Vorticella convallaria, a sessile peritrich having a body and spring-like stalk, is a model for a bioinspired actuator because of its remarkably fast (msec) and powerful contractions (nN). An example of a biological spring, the stalk converts biochemical energy to physical motion, but the mechanics of contraction are poorly understood. To evaluate contraction force, past models have assumed the body to be a sphere moving in quiescent water and have equated contraction force to drag force on the body described by Stokes' law. However, flow induced by contracting Vorticella does not satisfy conditions of Stokes' law because the flow is unsteady (Womersley number > 1) and bound with a solid substrate to which the cell is tethered. We develop a more rigorous model for contraction force evaluation by assuming the body to be a sphere unsteadily moving perpendicularly toward a solid surface. The model comprises quasi-steady drag force, added mass force and history force with wall effect correction terms for each force. Vorticella not only generates a maximum contraction force greater than Stokes' drag, but it also experiences drag force in the direction of contraction in the later stage of contraction due to the memory effect of water.
Ogilvie, Gordon I.
2016-06-01
> These lecture notes and example problems are based on a course given at the University of Cambridge in Part III of the Mathematical Tripos. Fluid dynamics is involved in a very wide range of astrophysical phenomena, such as the formation and internal dynamics of stars and giant planets, the workings of jets and accretion discs around stars and black holes and the dynamics of the expanding Universe. Effects that can be important in astrophysical fluids include compressibility, self-gravitation and the dynamical influence of the magnetic field that is `frozen in' to a highly conducting plasma. The basic models introduced and applied in this course are Newtonian gas dynamics and magnetohydrodynamics (MHD) for an ideal compressible fluid. The mathematical structure of the governing equations and the associated conservation laws are explored in some detail because of their importance for both analytical and numerical methods of solution, as well as for physical interpretation. Linear and nonlinear waves, including shocks and other discontinuities, are discussed. The spherical blast wave resulting from a supernova, and involving a strong shock, is a classic problem that can be solved analytically. Steady solutions with spherical or axial symmetry reveal the physics of winds and jets from stars and discs. The linearized equations determine the oscillation modes of astrophysical bodies, as well as their stability and their response to tidal forcing.
Magoules, Frederic
2011-01-01
Exploring new variations of classical methods as well as recent approaches appearing in the field, Computational Fluid Dynamics demonstrates the extensive use of numerical techniques and mathematical models in fluid mechanics. It presents various numerical methods, including finite volume, finite difference, finite element, spectral, smoothed particle hydrodynamics (SPH), mixed-element-volume, and free surface flow.Taking a unified point of view, the book first introduces the basis of finite volume, weighted residual, and spectral approaches. The contributors present the SPH method, a novel ap
Fluid dynamics an introduction
Rieutord, Michel
2015-01-01
This book is dedicated to readers who want to learn fluid dynamics from the beginning. It assumes a basic level of mathematics knowledge that would correspond to that of most second-year undergraduate physics students and examines fluid dynamics from a physicist’s perspective. As such, the examples used primarily come from our environment on Earth and, where possible, from astrophysics. The text is arranged in a progressive and educational format, aimed at leading readers from the simplest basics to more complex matters like turbulence and magnetohydrodynamics. Exercises at the end of each chapter help readers to test their understanding of the subject (solutions are provided at the end of the book), and a special chapter is devoted to introducing selected aspects of mathematics that beginners may not be familiar with, so as to make the book self-contained.
Pedlosky, Joseph
1979-01-01
The content of this book is based, largely, on the core curriculum in geophys ical fluid dynamics which I and my colleagues in the Department of Geophysical Sciences at The University of Chicago have taught for the past decade. Our purpose in developing a core curriculum was to provide to advanced undergraduates and entering graduate students a coherent and systematic introduction to the theory of geophysical fluid dynamics. The curriculum and the outline of this book were devised to form a sequence of courses of roughly one and a half academic years (five academic quarters) in length. The goal of the sequence is to help the student rapidly advance to the point where independent study and research are practical expectations. It quickly became apparent that several topics (e. g. , some aspects of potential theory) usually thought of as forming the foundations of a fluid-dynamics curriculum were merely classical rather than essential and could be, however sadly, dispensed with for our purposes. At the same ti...
Pedlosky, Joseph
1982-01-01
The content of this book is based, largely, on the core curriculum in geophys ical fluid dynamics which land my colleagues in the Department of Geophysical Sciences at The University of Chicago have taught for the past decade. Our purpose in developing a core curriculum was to provide to advanced undergraduates and entering graduate students a coherent and systematic introduction to the theory of geophysical fluid dynamics. The curriculum and the outline of this book were devised to form a sequence of courses of roughly one and a half academic years (five academic quarters) in length. The goal of the sequence is to help the student rapidly advance to the point where independent study and research are practical expectations. It quickly became apparent that several topics (e. g. , some aspects of potential theory) usually thought of as forming the foundations of a fluid-dynamics curriculum were merely classical rather than essential and could be, however sadly, dispensed with for our purposes. At the same tim...
Fundamentals of Geophysical Fluid Dynamics
McWilliams, James C.
2006-07-01
Earth's atmosphere and oceans exhibit complex patterns of fluid motion over a vast range of space and time scales. These patterns combine to establish the climate in response to solar radiation that is inhomogeneously absorbed by the materials comprising air, water, and land. Spontaneous, energetic variability arises from instabilities in the planetary-scale circulations, appearing in many different forms such as waves, jets, vortices, boundary layers, and turbulence. Geophysical fluid dynamics (GFD) is the science of all these types of fluid motion. This textbook is a concise and accessible introduction to GFD for intermediate to advanced students of the physics, chemistry, and/or biology of Earth's fluid environment. The book was developed from the author's many years of teaching a first-year graduate course at the University of California, Los Angeles. Readers are expected to be familiar with physics and mathematics at the level of general dynamics (mechanics) and partial differential equations. Covers the essential GFD required for atmospheric science and oceanography courses Mathematically rigorous, concise coverage of basic theory and applications to both oceans and atmospheres Author is a world expert; this book is based on the course he has taught for many years Exercises are included, with solutions available to instructors from solutions@cambridge.org
Essential Computational Fluid Dynamics
Zikanov, Oleg
2011-01-01
This book serves as a complete and self-contained introduction to the principles of Computational Fluid Dynamic (CFD) analysis. It is deliberately short (at approximately 300 pages) and can be used as a text for the first part of the course of applied CFD followed by a software tutorial. The main objectives of this non-traditional format are: 1) To introduce and explain, using simple examples where possible, the principles and methods of CFD analysis and to demystify the `black box’ of a CFD software tool, and 2) To provide a basic understanding of how CFD problems are set and
International Nuclear Information System (INIS)
Mihalas, D.; Weaver, R.
1982-01-01
The purpose of this paper is to give an overview of the role of radiation in the transport of energy and momentum in a combined matter-radiation fluid. The transport equation for a moving radiating fluid is presented in both a fully Eulerian and a fully Lagrangian formulation, along with conservation equations describing the dynamics of the fluid. Special attention is paid to the problem of deriving equations that are mutually consistent in each frame, and between frames, to 0(v/c). A detailed analysis is made to show that in situations of broad interest, terms that are formally of 0(v/c) actually dominate the solution, demonstrating that it is essential (1) to pay scrupulous attention to the question of the frame dependence in formulating the equations, and (2) to solve the equations to 0(v/c) in quite general circumstances. These points are illustrated in the context of the nonequilibrium radiation diffusion limit, and a sketch of how the Lagrangian equations are to be solved is presented
Beall, M. H.; van den Wijngaard, J. P. H. M.; van Gemert, M. J. C.; Ross, M. G.
2007-01-01
Water arrives in the mammalian gestation from the maternal circulation across the placenta. It then circulates between the fetal water compartments, including the fetal body compartments, the placenta and the amniotic fluid. Amniotic fluid is created by the flow of fluid from the fetal lung and
Park, Stephen; Li, Yebo
2015-05-01
Microalgal growth and systemic productivity is not only affected by environmental conditions such as temperature, irradiance, and nutrient concentrations, but also by physical processes such as fluid flow and particulate sedimentation. Modeling and simulating the system is a cost-effective way to predict the growth behavior under various environmental and physical conditions while determining effective engineering approaches to maximize productivity. Many mathematical models have been proposed to describe microalgal growth, while computational fluid dynamics (CFD) have been used to model the behavior of many fluid systems. Integrating the growth kinetics into a CFD model can help researchers understand the impact of a variety of parameters and determine what measures can be taken to overcome some obstacles in the aquaculture industry--self-shading, biomass sedimentation, and contamination--which prevent the production of high biomass yields. The aim of this study was to integrate physical and environmental effects to predict space- and time-dependent algal growth in industrial scale raceways. A commercial CFD software, ANSYS-Fluent 14.5, was used to solve the proposed models in regards to fluid flow, heat transfer, and nutrient balance. User-defined functions written in C language were used to incorporate the kinetic equations into a three-dimensional standard k-ε turbulence model of an open channel raceway system driven by a single paddlewheel. Simulated results were compared with light intensity, temperature, nutrient concentration, and algal biomass data acquired for 56 day from an industrial scale raceway pond constructed for the growth of Nannochloropsis salina and were observed to be in good agreement with one another. There was up to a 17.6% increase in simulated productivity when the incoming CO2 concentration was increased from 0.0006 to 0.150 g L(-1), while the effect of paddlewheel velocity was not significant. Sensitivity analysis showed that the model
Computational fluid dynamic applications
Energy Technology Data Exchange (ETDEWEB)
Chang, S.-L.; Lottes, S. A.; Zhou, C. Q.
2000-04-03
The rapid advancement of computational capability including speed and memory size has prompted the wide use of computational fluid dynamics (CFD) codes to simulate complex flow systems. CFD simulations are used to study the operating problems encountered in system, to evaluate the impacts of operation/design parameters on the performance of a system, and to investigate novel design concepts. CFD codes are generally developed based on the conservation laws of mass, momentum, and energy that govern the characteristics of a flow. The governing equations are simplified and discretized for a selected computational grid system. Numerical methods are selected to simplify and calculate approximate flow properties. For turbulent, reacting, and multiphase flow systems the complex processes relating to these aspects of the flow, i.e., turbulent diffusion, combustion kinetics, interfacial drag and heat and mass transfer, etc., are described in mathematical models, based on a combination of fundamental physics and empirical data, that are incorporated into the code. CFD simulation has been applied to a large variety of practical and industrial scale flow systems.
Palazzi, Elisa; Fraedrich, Klaus
2016-01-01
This volume provides an overview of the fluid aspects of the climate system, focusing on basic aspects as well as recent research developments. It will bring together contributions from diverse fields of the physical, mathematical and engineering sciences. The volume will be useful to doctorate students, postdocs and researchers working on different aspects of atmospheric, oceanic and environmental fluid dynamics. It will also be of interest to researchers interested in quantitatively understanding how fluid dynamics can be applied to the climate system, and to climate scientists willing to gain a deeper insight into the fluid mechanics underlying climate processes.
Basic developments in fluid dynamics
Holt, Maurice
2012-01-01
Basic Developments in Fluid Dynamics, Volume 2 focuses on the developments, approaches, methodologies, reactions, and processes involved in fluid dynamics, including sea motion, wave interactions, and motion of spheres in a viscous fluid.The selection first offers information on inviscid cavity and wake flows and weak-interaction theory of ocean waves. Discussions focus on steady and unsteady cavity flows, radiation balance, theory of weak interactions in random fields, interactions between gravity waves and the atmosphere, and interactions within the ocean. The text then examines low Reynolds
Fluid Dynamics of Bottle Filling
McGough, Patrick; Gao, Haijing; Appathurai, Santosh; Basaran, Osman
2011-11-01
Filling of bottles is a widely practiced operation in a large number of industries. Well known examples include filling of ``large'' bottles with shampoos and cleaners in the household products and beauty care industries and filling of ``small'' bottles in the pharmaceutical industry. Some bottle filling operations have recently drawn much attention from the fluid mechanics community because of the occurrence of a multitude of complex flow regimes, transitions, and instabilities such as mounding and coiling that occur as a bottle is filled with a fluid. In this talk, we present a primarily computational study of the fluid dynamical challenges that can arise during the rapid filling of bottles. Given the diversity of fluids used in filling applications, we consider four representative classes of fluids that exhibit Newtonian, shear-thinning, viscoelastic, and yield-stress rheologies. The equations governing the dynamics of bottle filling are solved either in their full 3D but axisymmetric form or using the slender-jet approximation.
Noncommutative geometry and fluid dynamics
International Nuclear Information System (INIS)
Das, Praloy; Ghosh, Subir
2016-01-01
In the present paper we have developed a Non-Commutative (NC) generalization of perfect fluid model from first principles, in a Hamiltonian framework. The noncommutativity is introduced at the Lagrangian (particle) coordinate space brackets and the induced NC fluid bracket algebra for the Eulerian (fluid) field variables is derived. Together with a Hamiltonian this NC algebra generates the generalized fluid dynamics that satisfies exact local conservation laws for mass and energy, thereby maintaining mass and energy conservation. However, nontrivial NC correction terms appear in the charge and energy fluxes. Other non-relativistic spacetime symmetries of the NC fluid are also discussed in detail. This constitutes the study of kinematics and dynamics of NC fluid. In the second part we construct an extension of the Friedmann-Robertson-Walker (FRW) cosmological model based on the NC fluid dynamics presented here. We outline the way in which NC effects generate cosmological perturbations bringing about anisotropy and inhomogeneity in the model. We also derive a NC extended Friedmann equation. (orig.)
Directory of Open Access Journals (Sweden)
E Lecarpentier
Full Text Available In the human placenta the maternal blood circulates in the intervillous space (IVS. The syncytiotrophoblast (STB is in direct contact with maternal blood. The wall shear stress (WSS exerted by the maternal blood flow on the STB has not been evaluated. Our objective was to determine the physiological WSS exerted on the surface of the STB during the third trimester of pregnancy.To gain insight into the shear stress levels that the STB is expected to experience in vivo, we have formulated three different computational models of varying levels of complexity that reflect different physical representations of the IVS. Computations of the flow fields in all models were performed using the CFD module of the finite element code COMSOL Multiphysics 4.4. The mean velocity of maternal blood in the IVS during the third trimester was measured in vivo with dynamic MRI (0.94±0.14 mm.s-1. To investigate if the in silico results are consistent with physiological observations, we studied the cytoadhesion of human parasitized (Plasmodium falciparum erythrocytes to primary human STB cultures, in flow conditions with different WSS values.The WSS applied to the STB is highly heterogeneous in the IVS. The estimated average values are relatively low (0.5±0.2 to 2.3±1.1 dyn.cm-2. The increase of WSS from 0.15 to 5 dyn.cm-2 was associated with a significant decrease of infected erythrocyte cytoadhesion. No cytoadhesion of infected erythrocytes was observed above 5 dyn.cm-2 applied for one hour.Our study provides for the first time a WSS estimation in the maternal placental circulation. In spite of high maternal blood flow rates, the average WSS applied at the surface of the chorionic villi is low (<5 dyn.cm-2. These results provide the basis for future physiologically-relevant in vitro studies of the biological effects of WSS on the STB.
Magnetic movement of biological fluid droplets
International Nuclear Information System (INIS)
Garcia, Antonio A.; Egatz-Gomez, Ana; Lindsay, Solitaire A.; Dominguez-Garcia, P.; Melle, Sonia; Marquez, Manuel; Rubio, Miguel A.; Picraux, S.T.; Yang, Dongqing; Aella, P.; Hayes, Mark A.; Gust, Devens; Loyprasert, Suchera; Vazquez-Alvarez, Terannie; Wang, Joseph
2007-01-01
Magnetic fields can be used to control the movement of aqueous drops on non-patterned, silicon nanowire superhydrophobic surfaces. Drops of aqueous and biological fluids are controlled by introducing magnetizable carbonyl iron microparticles into the liquid. Key elements of operations such as movement, coalescence, and splitting of water and biological fluid drops, as well as electrochemical measurement of an analyte are demonstrated. Superhydrophobic surfaces were prepared using vapor-liquid-solid (VLS) growth systems followed by coating with a perfluorinated hydrocarbon molecule. Drops were made from aqueous and biological fluid suspensions with magnetizable microparticle concentrations ranging from 0.1 to 10 wt%
Magnetic movement of biological fluid droplets
Energy Technology Data Exchange (ETDEWEB)
Garcia, Antonio A. [Harrington Department of Bioengineering, Arizona State University, Tempe, AZ 85287 (United States)]. E-mail: tony.garcia@asu.edu; Egatz-Gomez, Ana [Harrington Department of Bioengineering, Arizona State University, Tempe, AZ 85287 (United States); Lindsay, Solitaire A. [Harrington Department of Bioengineering, Arizona State University, Tempe, AZ 85287 (United States); Dominguez-Garcia, P. [Departamento de Fisica Fundamental, UNED, Senda del Rey 9, Madrid 28040 (Spain); Melle, Sonia [Harrington Department of Bioengineering, Arizona State University, Tempe, AZ 85287 (United States); Departamento de Optica, Universidad Complutense de Madrid, Arcos de Jalon s/n, Madrid 28037 (Spain); Marquez, Manuel [Harrington Department of Bioengineering, Arizona State University, Tempe, AZ 85287 (United States); Research Center, Philip Morris USA, Richmond, VA 23234 (United States); Rubio, Miguel A. [Departamento de Fisica Fundamental, UNED, Senda del Rey 9, Madrid 28040 (Spain); Picraux, S.T. [Department of Chemical and Materials Engineering, Arizona State University, Tempe, AZ 85287 (United States); Los Alamos National Laboratory, MST-CINT, Los Alamos, NM 87545 (United States); Yang, Dongqing [Department of Chemical and Materials Engineering, Arizona State University, Tempe, AZ 85287 (United States); Aella, P. [Department of Chemical and Materials Engineering, Arizona State University, Tempe, AZ 85287 (United States); Hayes, Mark A. [Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 8528 (United States); Gust, Devens [Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 8528 (United States); Loyprasert, Suchera [Biodesign Institute, Arizona State University, Tempe, AZ 85287 (United States); Vazquez-Alvarez, Terannie [Biodesign Institute, Arizona State University, Tempe, AZ 85287 (United States); Wang, Joseph [Biodesign Institute, Arizona State University, Tempe, AZ 85287 (United States)
2007-04-15
Magnetic fields can be used to control the movement of aqueous drops on non-patterned, silicon nanowire superhydrophobic surfaces. Drops of aqueous and biological fluids are controlled by introducing magnetizable carbonyl iron microparticles into the liquid. Key elements of operations such as movement, coalescence, and splitting of water and biological fluid drops, as well as electrochemical measurement of an analyte are demonstrated. Superhydrophobic surfaces were prepared using vapor-liquid-solid (VLS) growth systems followed by coating with a perfluorinated hydrocarbon molecule. Drops were made from aqueous and biological fluid suspensions with magnetizable microparticle concentrations ranging from 0.1 to 10 wt%.
Computational Fluid Dynamics in Ventilation
DEFF Research Database (Denmark)
Nielsen, Peter V.; Allard, Francis; Awbi, Hazim B.
2008-01-01
Computational Fluid Dynamics in Ventilation Design is a new title in the is a new title in the REHVA guidebook series. The guidebook is written for people who need to use and discuss results based on CFD predictions, and it gives insight into the subject for those who are not used to work with CFD...
Electromagnetics and Fluid Dynamics
Gaitonde, Datta
1998-01-01
Previous efforts focused on developing tools for design of low observables were sustained. The final product was the maturation of a high-order accurate finite-volume based code to solve Maxwell's equations. One of the primary achievements was the development and implementation of efficient filtering techniques which enhance the robustness of high-order and optimized schemes without significant adverse impact on accuracy. This has eliminated the stability barrier which restrains the common use of high-order schemes for conservative wave propagation phenomena on curvilinear meshes. A study was performed of crossing shock interactions under conditions of increasing interaction strength and asymmetry. In the first category, the observed computed topological bifurcations were correlated with the formation of various lines of coalescence and divergence evident in experimental and computed surf-ace oil maps. ne flow structure arising from asymmetric interactions was investigated with particular emphasis on: 1) vorticity dynamics, 2) shock-structure and 3) sidewall vortex loading. Several efforts of the prior year were successfully published in archival journals. The high-order algorithms developed for CEM have been implemented into the FDL3DI CFD code are presently undergoing extensive testing. Preliminary results are highly encouraging.
Visualization of Computational Fluid Dynamics
Gerald-Yamasaki, Michael; Hultquist, Jeff; Bryson, Steve; Kenwright, David; Lane, David; Walatka, Pamela; Clucas, Jean; Watson, Velvin; Lasinski, T. A. (Technical Monitor)
1995-01-01
Scientific visualization serves the dual purpose of exploration and exposition of the results of numerical simulations of fluid flow. Along with the basic visualization process which transforms source data into images, there are four additional components to a complete visualization system: Source Data Processing, User Interface and Control, Presentation, and Information Management. The requirements imposed by the desired mode of operation (i.e. real-time, interactive, or batch) and the source data have their effect on each of these visualization system components. The special requirements imposed by the wide variety and size of the source data provided by the numerical simulation of fluid flow presents an enormous challenge to the visualization system designer. We describe the visualization system components including specific visualization techniques and how the mode of operation and source data requirements effect the construction of computational fluid dynamics visualization systems.
Directory of Open Access Journals (Sweden)
Linsen Xu
2013-10-01
Full Text Available A kinematics analysis of a biologically-inspired biped robot is carried out, and the trajectory of the robot foot is understood. For calculating the pressure distribution across a robot foot before touching the surface of water, the compression flow of air and the depression motion of the water surface are considered. The pressure model after touching the water surface has been built according to the theory of rigid body planar motion. The multi-material ALE algorithm is applied to emulate the course of the foot slapping water. The simulation results indicate that the model of the bionic robot can satisfy the water-running function. The real prototype of the robot is manufactured to test its function of running on water. When the biped robot is running on water, the average force generated by the propulsion mechanism is about 1.3N. The experimental results show that the propulsion system can satisfy the requirement of biped robot running on water.
Complex fluids in biological systems experiment, theory, and computation
2015-01-01
This book serves as an introduction to the continuum mechanics and mathematical modeling of complex fluids in living systems. The form and function of living systems are intimately tied to the nature of surrounding fluid environments, which commonly exhibit nonlinear and history dependent responses to forces and displacements. With ever-increasing capabilities in the visualization and manipulation of biological systems, research on the fundamental phenomena, models, measurements, and analysis of complex fluids has taken a number of exciting directions. In this book, many of the world’s foremost experts explore key topics such as: Macro- and micro-rheological techniques for measuring the material properties of complex biofluids and the subtleties of data interpretation Experimental observations and rheology of complex biological materials, including mucus, cell membranes, the cytoskeleton, and blood The motility of microorganisms in complex fluids and the dynamics of active suspensions Challenges and solut...
Fluid dynamics and vibration of tube banks in fluid flow
International Nuclear Information System (INIS)
Zukauskas, A.; Ulinskas, R.; Katinas, V.
1988-01-01
This work presents results derived in fluid dynamics, hydraulic drag and flow-induced vibrations within transverse and yawed tube banks. The studies encompass banks of smooth, rough and finned tubes at Reynolds numbers from 1 to 2x10/sup 6/. Highlighted in the text are fluid dynamic parameters of tube banks measured at inter-tube spaces and tube surfaces
Geophysical fluid dynamics: whence, whither and why?
Vallis, Geoffrey K
2016-08-01
This article discusses the role of geophysical fluid dynamics (GFD) in understanding the natural environment, and in particular the dynamics of atmospheres and oceans on Earth and elsewhere. GFD, as usually understood, is a branch of the geosciences that deals with fluid dynamics and that, by tradition, seeks to extract the bare essence of a phenomenon, omitting detail where possible. The geosciences in general deal with complex interacting systems and in some ways resemble condensed matter physics or aspects of biology, where we seek explanations of phenomena at a higher level than simply directly calculating the interactions of all the constituent parts. That is, we try to develop theories or make simple models of the behaviour of the system as a whole. However, these days in many geophysical systems of interest, we can also obtain information for how the system behaves by almost direct numerical simulation from the governing equations. The numerical model itself then explicitly predicts the emergent phenomena-the Gulf Stream, for example-something that is still usually impossible in biology or condensed matter physics. Such simulations, as manifested, for example, in complicated general circulation models, have in some ways been extremely successful and one may reasonably now ask whether understanding a complex geophysical system is necessary for predicting it. In what follows we discuss such issues and the roles that GFD has played in the past and will play in the future.
ICFD - Interdisciplinary Computational Fluid Dynamics
International Nuclear Information System (INIS)
Hankey, W.L.
1985-01-01
Interdisciplinary Computational Fluid Dynamics is that field in which the Navier-Stokes equations are coupled to another set of equations for the solution of interaction problems. Although it is currently possible to apply numerical algorithms and grid generation methods to such problems, together with the conservation form for governing equations and arrangements of field data which exploit vector processor hardwares, novel technology is called for in the modeling of complex interface boundary conditions and the incorporation of constitutive relationships for state variables and transport processes. It is also necessary to model such subgrid scale phenomena as turbulence, evaporation, atomization, devolatization, nucleation, chemical reactions, surface tension, and surface roughness. 33 references
Computational Fluid Dynamics in Ventilation
DEFF Research Database (Denmark)
Nielsen, Peter V.; Allard, Francis; Awbi, Hazim B.
2008-01-01
Computational Fluid Dynamics in Ventilation Design is a new title in the is a new title in the REHVA guidebook series. The guidebook is written for people who need to use and discuss results based on CFD predictions, and it gives insight into the subject for those who are not used to work with CFD....... The guidebook is also written for people working with CFD which have to be more aware of how this numerical method is applied in the area of ventilation. The guidebook has, for example, chapters that are very important for CFD quality control in general and for the quality control of ventilation related...
Fluid Dynamics of the Heart and its Valves
Peskin, Charles S.
1997-11-01
The fluid dynamics of the heart involve the interaction of blood, a viscous incompressible fluid, with the flexible, elastic, fiber-reinforced heart valve leaflets that are immersed in that fluid. Neither the fluid motion nor the valve leaflet motion are known in advance: both must be computed simultaneously by solving their coupled equations of motion. This can be done by the immersed boundary method(Peskin CS and McQueen DM: A general method for the computer simulation of biological systems interacting with fluids. In: Biological Fluid Dynamics (Ellington CP and Pedley TJ, eds.), The Company of Biologists Limited, Cambridge UK, 1995, pp. 265-276.), which can be extended to incorporate the contractile fiber architecture of the muscular heart walls as well as the valve leaflets and the blood. In this way we arrive at a three-dimensional computer model of the heart(Peskin CS and McQueen DM: Fluid dynamics of the heart and its valves. In: Case Studies in Mathematical Modeling: Ecology, Physiology, and Cell Biology (Othmer HG, Adler FR, Lewis MA, and Dallon JC, eds.), Prentice-Hall, Englewood Cliffs NJ, 1996, pp. 309-337.), which can be used as a test chamber for the design of prosthetic cardiac valves, and also to study the function of the heart in health and in disease. Numerical solutions of the equations of cardiac fluid dynamics obtained by the immersed boundary method will be presented in the form of a video animation of the beating heart.
Computational methods for fluid dynamics
Ferziger, Joel H
2002-01-01
In its 3rd revised and extended edition the book offers an overview of the techniques used to solve problems in fluid mechanics on computers and describes in detail those most often used in practice. Included are advanced methods in computational fluid dynamics, like direct and large-eddy simulation of turbulence, multigrid methods, parallel computing, moving grids, structured, block-structured and unstructured boundary-fitted grids, free surface flows. The 3rd edition contains a new section dealing with grid quality and an extended description of discretization methods. The book shows common roots and basic principles for many different methods. The book also contains a great deal of practical advice for code developers and users, it is designed to be equally useful to beginners and experts. The issues of numerical accuracy, estimation and reduction of numerical errors are dealt with in detail, with many examples. A full-feature user-friendly demo-version of a commercial CFD software has been added, which ca...
Principles of computational fluid dynamics
Wesseling, Pieter
2001-01-01
The book is aimed at graduate students, researchers, engineers and physicists involved in flow computations. An up-to-date account is given of the present state-of-the-art of numerical methods employed in computational fluid dynamics. The underlying numerical principles are treated with a fair amount of detail, using elementary mathematical analysis. Attention is given to difficulties arising from geometric complexity of the flow domain and of nonuniform structured boundary-fitted grids. Uniform accuracy and efficiency for singular perturbation problems is studied, pointing the way to accurate computation of flows at high Reynolds number. Much attention is given to stability analysis, and useful stability conditions are provided, some of them new, for many numerical schemes used in practice. Unified methods for compressible and incompressible flows are discussed. Numerical analysis of the shallow-water equations is included. The theory of hyperbolic conservation laws is treated. Godunov's order barrier and ho...
Introducing fluid dynamics using dimensional analysis
DEFF Research Database (Denmark)
Jensen, Jens Højgaard
2013-01-01
Many aspects of fluid dynamics can be introduced using dimensional analysis, combined with some basic physical principles. This approach is concise and allows exploration of both the laminar and turbulent limits—including important phenomena that are not normally dealt with when fluid dynamics...
Fluid dynamics theory, computation, and numerical simulation
Pozrikidis, C
2001-01-01
Fluid Dynamics Theory, Computation, and Numerical Simulation is the only available book that extends the classical field of fluid dynamics into the realm of scientific computing in a way that is both comprehensive and accessible to the beginner The theory of fluid dynamics, and the implementation of solution procedures into numerical algorithms, are discussed hand-in-hand and with reference to computer programming This book is an accessible introduction to theoretical and computational fluid dynamics (CFD), written from a modern perspective that unifies theory and numerical practice There are several additions and subject expansions in the Second Edition of Fluid Dynamics, including new Matlab and FORTRAN codes Two distinguishing features of the discourse are solution procedures and algorithms are developed immediately after problem formulations are presented, and numerical methods are introduced on a need-to-know basis and in increasing order of difficulty Matlab codes are presented and discussed for a broad...
Fluid dynamics of bubbly flows
International Nuclear Information System (INIS)
Ziegenhein, Thomas
2016-01-01
Bubbly flows can be found in many applications in chemical, biological and power engineering. Reliable simulation tools of such flows that allow the design of new processes and optimization of existing one are therefore highly desirable. CFD-simulations applying the multi-fluid approach are very promising to provide such a design tool for complete facilities. In the multi-fluid approach, however, closure models have to be formulated to model the interaction between the continuous and dispersed phase. Due to the complex nature of bubbly flows, different phenomena have to be taken into account and for every phenomenon different closure models exist. Therefore, reliable predictions of unknown bubbly flows are not yet possible with the multi-fluid approach. A strategy to overcome this problem is to define a baseline model in which the closure models including the model constants are fixed so that the limitations of the modeling can be evaluated by validating it on different experiments. Afterwards, the shortcomings are identified so that the baseline model can be stepwise improved without losing the validity for the already validated cases. This development of a baseline model is done in the present work by validating the baseline model developed at the Helmholtz-Zentrum Dresden-Rossendorf mainly basing on experimental data for bubbly pipe flows to bubble columns, bubble plumes and air-lift reactors that are relevant in chemical and biological engineering applications. In the present work, a large variety of such setups is used for validation. The buoyancy driven bubbly flows showed thereby a transient behavior on the scale of the facility. Since such large scales are characterized by the geometry of the facility, turbulence models cannot describe them. Therefore, the transient simulation of bubbly flows with two equation models based on the unsteady Reynolds-averaged Navier-Stokes equations is investigated. In combination with the before mentioned baseline model these
Principles of computational fluid dynamics
International Nuclear Information System (INIS)
Wesseling, P.
2001-01-01
The book is aimed at graduate students, researchers, engineers and physicists involved in flow computations. An up-to-date account is given of the present state- of-the-art of numerical methods employed in computational fluid dynamics. The underlying numerical principles are treated with a fair amount of detail, using elementary mathematical analysis. Attention is given to difficulties arising from geometric complexity of the flow domain and of nonuniform structured boundary-fitted grids. Uniform accuracy and efficiency for singular perturbation problems is studied, pointing the way to accurate computation of flows at high Reynolds number. Much attention is given to stability analysis, and useful stability conditions are provided, some of them new, for many numerical schemes used in practice. Unified methods for compressible and incompressible flows are discussed. Numerical analysis of the shallow-water equations is included. The theory of hyperbolic conservation laws is treated. Godunov's order barrier and how to overcome it by means of slope-limited schemes is discussed. An introduction is given to efficient iterative solution methods, using Krylov subspace and multigrid acceleration. Many pointers are given to recent literature, to help the reader to quickly reach the current research frontier. (orig.)
Fluid dynamics of Ribbed Annuli
International Nuclear Information System (INIS)
McCreery, G. E.; Pink, R. J.; Condie, K. G.; McEligot, D. M.
2003-01-01
Typical advanced gas-cooled reactor designs use periodic spacer ribs to center rods in circular cooling channels, e.g., as for control rods (General Atomics and others) and fuel rods (HTTR). In contrast to classical studies of axisymmetric annuli, the flow becomes three-dimensional but is typically periodic in the circumferential direction and - in some cases - in the streamwise direction. Fundamental measurements have been obtained for two idealizations of these complex geometries: an annulus with three ribs circumferentially and one with four. Laser Doppler Velocimetry (LDV) was employed with INEEL's unique Matched-Index-of-Refraction (MIR) flow facility to determine the velocity and turbulence fields. The initial experiment was aimed at obtaining benchmark data to test the capabilities of CFD (Computational Fluid Dynamics) codes to handle ribbed annular geometries without the complications of turbulent transport. The Reynolds number was about 1120. These conditions correspond to some stages during a pressurized cooldown (LOFA) event. Power spectral densities were obtained to determine the eddy shedding frequency downstream of the ribs. For the second experiment LDV measurements were obtained in another ribbed-annular model at a higher flow rate. For this nominally turbulent flow, evidence of laminarization appears in the flow converging to pass between ribs. The measurements indicated flow details which could be useful for assessment of CFD codes
Phase space density representations in fluid dynamics
International Nuclear Information System (INIS)
Ramshaw, J.D.
1989-01-01
Phase space density representations of inviscid fluid dynamics were recently discussed by Abarbanel and Rouhi. Here it is shown that such representations may be simply derived and interpreted by means of the Liouville equation corresponding to the dynamical system of ordinary differential equations that describes fluid particle trajectories. The Hamiltonian and Poisson bracket for the phase space density then emerge as immediate consequences of the corresponding structure of the dynamics. For barotropic fluids, this approach leads by direct construction to the formulation presented by Abarbanel and Rouhi. Extensions of this formulation to inhomogeneous incompressible fluids and to fluids in which the state equation involves an additional transported scalar variable are constructed by augmenting the single-particle dynamics and phase space to include the relevant additional variable
An introduction to Computational Fluid Dynamics
DEFF Research Database (Denmark)
Sørensen, Lars Schiøtt
1999-01-01
CFD is the shortname for Computational Fluid Dynamics and is a numerical method by means of which we can analyze systems containing fluids. For instance systems dealing with heat flow or smoke control systems acting when a fire occur in a building.......CFD is the shortname for Computational Fluid Dynamics and is a numerical method by means of which we can analyze systems containing fluids. For instance systems dealing with heat flow or smoke control systems acting when a fire occur in a building....
Computational Fluid Dynamics and Room Air Movement
DEFF Research Database (Denmark)
Nielsen, Peter Vilhelm
2004-01-01
Nielsen, P.V. Computational Fluid Dynamics and Room Air Movement. Indoor Air, International Journal of Indoor Environment and Health, Vol. 14, Supplement 7, pp. 134-143, 2004. ABSTRACT Computational Fluid Dynamics (CFD) and new developments of CFD in the indoor environment as well as quality...... considerations are important elements in the study of energy consumption, thermal comfort and indoor air quality in buildings. The paper discusses the quality level of Computational Fluid Dynamics and the involved schemes (first, second and third order schemes) by the use of the Smith and Hutton problem...
Experimental and theoretical advances in fluid dynamics
Klapp, Jaime; Fuentes, Oscar Velasco
2011-01-01
The book is comprised of lectures and selected contributions presented at the Enzo Levi and XVI Annual Meeting of the Fluid Dynamic Division of the Mexican Physical Society in 2010. It is aimed at fourth year undergraduate and graduate students, as well as scientists in the fields of physics, engineering and chemistry with an interest in fluid dynamics from the experimental and theoretical point of view. The lectures are introductory and avoid the use of complicated mathematics. The other selected contributions are also geared to fourth year undergraduate and graduate students. The fluid dynam
Knotted solutions, from electromagnetism to fluid dynamics
Alves, Daniel W. F.; Hoyos, Carlos; Nastase, Horatiu; Sonnenschein, Jacob
2017-11-01
Knotted solutions to electromagnetism and fluid dynamics are investigated, based on relations we find between the two subjects. We can write fluid dynamics in electromagnetism language, but only on an initial surface, or for linear perturbations, and we use this map to find knotted fluid solutions, as well as new electromagnetic solutions. We find that knotted solutions of Maxwell electromagnetism are also solutions of more general nonlinear theories, like Born-Infeld, and including ones which contain quantum corrections from couplings with other modes, like Euler-Heisenberg and string theory DBI. Null configurations in electromagnetism can be described as a null pressureless fluid, and from this map we can find null fluid knotted solutions. A type of nonrelativistic reduction of the relativistic fluid equations is described, which allows us to find also solutions of the (nonrelativistic) Euler’s equations.
Bubble dynamics equations in Newton fluid
International Nuclear Information System (INIS)
Xiao, J
2008-01-01
For the high-speed flow of Newton fluid, bubble is produced and expanded when it moves toward the surface of fluid. Bubble dynamics is a very important research field to understand the intrinsic feature of bubble production and motion. This research formulates the bubble expansion by expansion-local rotation transformation, which can be calculated by the measured velocity field. Then, the related dynamic equations are established to describe the interaction between the fluid and the bubble. The research shows that the bubble production condition can be expressed by critical vortex value and fluid pressure; and the bubble expansion rate can be obtained by solving the non-linear dynamic equation of bubble motion. The results may help the related research as it shows a special kind of fluid motion in theoretic sense. As an application example, the nanofiber radium-voltage relation and threshold voltage-surface tension relation in electrospinning process are discussed
Dynamic fluid loss characteristics of foam fracturing fluids
Energy Technology Data Exchange (ETDEWEB)
Harris, P.C.
1982-09-01
Dynamic fluid loss measurements were conducted on core samples ranging in permeability between 0.02 to 140 md. These tests were run to measure the effect of several parameters on the foam fluid loss coefficients. The parameters tested were: core permeability, gel concentration in the liquid phase, foam quality, temperature, core length and differential test pressure. The type of foam that is used in most conventional fracturing treatments is a wall building fluid. Although this foam has excellent inherent fluid loss properties, the fluid loss values reported in this paper more closely resemble those of conventional fracturing fluids than reported earlier. These values have been used in the successful design of field fracturing treatments. These data support the mechanism of two phase flow in porous media suggested by Holm. The fluid passing through the cores was rich in liquid phase with composition proportional to the viscosity of the liquid phase. The broad range of fluid loss coefficients for foam calculated in these tests are intermediate in value to those reported in similar tests by Blauer and Kohlhaas, who obtained lower values, and King, who obtained higher values.
Fluid dynamics computer programs for NERVA turbopump
Brunner, J. J.
1972-01-01
During the design of the NERVA turbopump, numerous computer programs were developed for the analyses of fluid dynamic problems within the machine. Program descriptions, example cases, users instructions, and listings for the majority of these programs are presented.
Parallel processing for fluid dynamics applications
International Nuclear Information System (INIS)
Johnson, G.M.
1989-01-01
The impact of parallel processing on computational science and, in particular, on computational fluid dynamics is growing rapidly. In this paper, particular emphasis is given to developments which have occurred within the past two years. Parallel processing is defined and the reasons for its importance in high-performance computing are reviewed. Parallel computer architectures are classified according to the number and power of their processing units, their memory, and the nature of their connection scheme. Architectures which show promise for fluid dynamics applications are emphasized. Fluid dynamics problems are examined for parallelism inherent at the physical level. CFD algorithms and their mappings onto parallel architectures are discussed. Several example are presented to document the performance of fluid dynamics applications on present-generation parallel processing devices
Relativistic Fluid Dynamics Far From Local Equilibrium.
Romatschke, Paul
2018-01-05
Fluid dynamics is traditionally thought to apply only to systems near local equilibrium. In this case, the effective theory of fluid dynamics can be constructed as a gradient series. Recent applications of resurgence suggest that this gradient series diverges, but can be Borel resummed, giving rise to a hydrodynamic attractor solution which is well defined even for large gradients. Arbitrary initial data quickly approaches this attractor via nonhydrodynamic mode decay. This suggests the existence of a new theory of far-from-equilibrium fluid dynamics. In this Letter, the framework of fluid dynamics far from local equilibrium for a conformal system is introduced, and the hydrodynamic attractor solutions for resummed Baier-Romatschke-Son-Starinets-Stephanov theory, kinetic theory in the relaxation time approximation, and strongly coupled N=4 super Yang-Mills theory are identified for a system undergoing Bjorken flow.
Relativistic Fluid Dynamics Far From Local Equilibrium
Romatschke, Paul
2018-01-01
Fluid dynamics is traditionally thought to apply only to systems near local equilibrium. In this case, the effective theory of fluid dynamics can be constructed as a gradient series. Recent applications of resurgence suggest that this gradient series diverges, but can be Borel resummed, giving rise to a hydrodynamic attractor solution which is well defined even for large gradients. Arbitrary initial data quickly approaches this attractor via nonhydrodynamic mode decay. This suggests the existence of a new theory of far-from-equilibrium fluid dynamics. In this Letter, the framework of fluid dynamics far from local equilibrium for a conformal system is introduced, and the hydrodynamic attractor solutions for resummed Baier-Romatschke-Son-Starinets-Stephanov theory, kinetic theory in the relaxation time approximation, and strongly coupled N =4 super Yang-Mills theory are identified for a system undergoing Bjorken flow.
Nuclear fluid dynamics and TDHF
International Nuclear Information System (INIS)
Koehler, H.S.
1982-01-01
In some previous reports a modified TDHF (Time Dependent Hartree-Fock) equation including a collision term was introduced. The collisions were included in the relaxation-time approximation familiar in classical transport theory. In plasma-physics it is often referred to as the Krook-model. The author explores the approximate nature of, and the possible computational advantage of revamping the modified TDHF-equation into fluid-equations, by truncating the moment-expansion of the Wigner-function. In the fluid-equations that are derived the mean field and the relaxation time are both maintained explicitly. The pressure tensor is allowed to be anisotropic, i.e., the fluid is viscous. Only in the limit of a very short relaxation time (approximately 10 -23 s) may the isotropic (non-viscous) approximation be acceptable. The fluid-equations are tested by comparing computed results with those obtained with the modified TDHF. It is concluded that the fluid-equations are a viable alternative. Some differences can be attributed to the neglect of the higher moments of the momentum-distribution in the fluid-equations. Others are due to other approximations necessary in the truncation. (Auth.)
Technical Competencies Applied in Experimental Fluid Dynamics
Tagg, Randall
2017-11-01
The practical design, construction, and operation of fluid dynamics experiments require a broad range of competencies. Three types are instrumental, procedural, and design. Respective examples would be operation of a spectrum analyzer, soft-soldering or brazing flow plumbing, and design of a small wind tunnel. Some competencies, such as the selection and installation of pumping systems, are unique to fluid dynamics and fluids engineering. Others, such as the design and construction of electronic amplifiers or optical imaging systems, overlap with other fields. Thus the identification and development of learning materials and methods for instruction are part of a larger effort to identify competencies needed in active research and technical innovation.
Nonlinear dynamics in biological systems
Carballido-Landeira, Jorge
2016-01-01
This book presents recent research results relating to applications of nonlinear dynamics, focusing specifically on four topics of wide interest: heart dynamics, DNA/RNA, cell mobility, and proteins. The book derives from the First BCAM Workshop on Nonlinear Dynamics in Biological Systems, held in June 2014 at the Basque Center of Applied Mathematics (BCAM). At this international meeting, researchers from different but complementary backgrounds, including molecular dynamics, physical chemistry, bio-informatics and biophysics, presented their most recent results and discussed the future direction of their studies using theoretical, mathematical modeling and experimental approaches. Such was the level of interest stimulated that the decision was taken to produce this publication, with the organizers of the event acting as editors. All of the contributing authors are researchers working on diverse biological problems that can be approached using nonlinear dynamics. The book will appeal especially to applied math...
Modern fluid dynamics for physics and astrophysics
Regev, Oded; Yecko, Philip A
2016-01-01
This book grew out of the need to provide students with a solid introduction to modern fluid dynamics. It offers a broad grounding in the underlying principles and techniques used, with some emphasis on applications in astrophysics and planetary science. The book comprehensively covers recent developments, methods and techniques, including, for example, new ideas on transitions to turbulence (via transiently growing stable linear modes), new approaches to turbulence (which remains the enigma of fluid dynamics), and the use of asymptotic approximation methods, which can give analytical or semi-analytical results and complement fully numerical treatments. The authors also briefly discuss some important considerations to be taken into account when developing a numerical code for computer simulation of fluid flows. Although the text is populated throughout with examples and problems from the field of astrophysics and planetary science, the text is eminently suitable as a general introduction to fluid dynamics. It...
International Conference on Mathematical Fluid Dynamics
Suzuki, Yukihito
2016-01-01
This volume presents original papers ranging from an experimental study on cavitation jets to an up-to-date mathematical analysis of the Navier-Stokes equations for free boundary problems, reflecting topics featured at the International Conference on Mathematical Fluid Dynamics, Present and Future, held 11–14 November 2014 at Waseda University in Tokyo. The contributions address subjects in one- and two-phase fluid flows, including cavitation, liquid crystal flows, plasma flows, and blood flows. Written by internationally respected experts, these papers highlight the connections between mathematical, experimental, and computational fluid dynamics. The book is aimed at a wide readership in mathematics and engineering, including researchers and graduate students interested in mathematical fluid dynamics.
Advanced Computational Fluid Dynamics (CFD)
National Aeronautics and Space Administration — It is time for the next generation of aerothermodynamic CFD software, including unstructured gridding, low dissipation fluxes, dynamic simulations, and modern...
Vortex dynamics in plasmas and fluids
DEFF Research Database (Denmark)
Juul Rasmussen, J.; Lynov, Jens-Peter; Hesthaven, J.S.
1994-01-01
The existence and dynamics of vortical structures in both homogeneous and inhomogeneous systems will be discussed. In particular the dynamics of monopolar and dipolar vortices in a plasma with nonuniform density and in a rotating fluid with varying Coriolis force is described. The role of vortical...
Díez, G; Soto, M; Blanco, J M
2015-07-01
This study characterized the morphology, density and orientation of the dermal denticles along the body of a shortfin mako shark Isurus oxyrinchus and identified the hydrodynamic parameters of its body through a computational fluid-dynamics model. The study showed a great variability in the morphology, size, shape, orientation and density of dermal denticles along the body of I. oxyrinchus. There was a significant higher density in dorsal and ventral areas of the body and their highest angular deviations were found in the lower part of the mouth and in the areas between the pre-caudal pit and the second dorsal and pelvic fins. A detailed three-dimensional geometry from a scanned body of a shark was carried out to evaluate the hydrodynamic properties such as drag coefficient, lift coefficient and superficial (skin) friction coefficient of the skin together with flow velocity field, according to different roughness coefficients simulating the effect of the dermal denticles. This preliminary approach contributed to detailed information of the denticle interactions. As the height of the denticles was increased, flow velocity and the effect of lift decreased whereas drag increased. The highest peaks of skin friction coefficient were observed around the pectoral fins. © 2015 The Fisheries Society of the British Isles.
Interfacial gauge methods for incompressible fluid dynamics
Saye, Robert
2016-01-01
Designing numerical methods for incompressible fluid flow involving moving interfaces, for example, in the computational modeling of bubble dynamics, swimming organisms, or surface waves, presents challenges due to the coupling of interfacial forces with incompressibility constraints. A class of methods, denoted interfacial gauge methods, is introduced for computing solutions to the corresponding incompressible Navier-Stokes equations. These methods use a type of “gauge freedom” to reduce the numerical coupling between fluid velocity, pressure, and interface position, allowing high-order accurate numerical methods to be developed more easily. Making use of an implicit mesh discontinuous Galerkin framework, developed in tandem with this work, high-order results are demonstrated, including surface tension dynamics in which fluid velocity, pressure, and interface geometry are computed with fourth-order spatial accuracy in the maximum norm. Applications are demonstrated with two-phase fluid flow displaying fine-scaled capillary wave dynamics, rigid body fluid-structure interaction, and a fluid-jet free surface flow problem exhibiting vortex shedding induced by a type of Plateau-Rayleigh instability. The developed methods can be generalized to other types of interfacial flow and facilitate precise computation of complex fluid interface phenomena. PMID:27386567
Interfacial gauge methods for incompressible fluid dynamics.
Saye, Robert
2016-06-01
Designing numerical methods for incompressible fluid flow involving moving interfaces, for example, in the computational modeling of bubble dynamics, swimming organisms, or surface waves, presents challenges due to the coupling of interfacial forces with incompressibility constraints. A class of methods, denoted interfacial gauge methods, is introduced for computing solutions to the corresponding incompressible Navier-Stokes equations. These methods use a type of "gauge freedom" to reduce the numerical coupling between fluid velocity, pressure, and interface position, allowing high-order accurate numerical methods to be developed more easily. Making use of an implicit mesh discontinuous Galerkin framework, developed in tandem with this work, high-order results are demonstrated, including surface tension dynamics in which fluid velocity, pressure, and interface geometry are computed with fourth-order spatial accuracy in the maximum norm. Applications are demonstrated with two-phase fluid flow displaying fine-scaled capillary wave dynamics, rigid body fluid-structure interaction, and a fluid-jet free surface flow problem exhibiting vortex shedding induced by a type of Plateau-Rayleigh instability. The developed methods can be generalized to other types of interfacial flow and facilitate precise computation of complex fluid interface phenomena.
Fluid Mechanics of Biological Surfaces and their Technological Application
Bechert, D. W.; Bruse, M.; Hage, W.; Meyer, R.
A survey is given on fluid-dynamic effects caused by the structure and properties of biological surfaces. It is demonstrated that the results of investigations aiming at technological applications can also provide insights into biophysical phenomena. Techniques are described both for reducing wall shear stresses and for controlling boundary-layer separation. (a) Wall shear stress reduction was investigated experimentally for various riblet surfaces including a shark skin replica. The latter consists of 800 plastic model scales with compliant anchoring. Hairy surfaces are also considered, and surfaces in which the no-slip condition is modified. Self-cleaning surfaces such as that of lotus leaves represent an interesting option to avoid fluid-dynamic deterioration by the agglomeration of dirt. An example of technological implementation is discussed for riblets in long-range commercial aircraft. (b) Separation control is also an important issue in biology. After a few brief comments on vortex generators, the mechanism of separation control by bird feathers is described in detail. Self-activated movable flaps (=artificial bird feathers) represent a high-lift system enhancing the maximum lift of airfoils by about 20%. This is achieved without perceivable deleterious effects under cruise conditions. Finally, flight experiments on an aircraft with laminar wing and movable flaps are presented.
Dynamical systems in population biology
Zhao, Xiao-Qiang
2017-01-01
This research monograph provides an introduction to the theory of nonautonomous semiflows with applications to population dynamics. It develops dynamical system approaches to various evolutionary equations such as difference, ordinary, functional, and partial differential equations, and pays more attention to periodic and almost periodic phenomena. The presentation includes persistence theory, monotone dynamics, periodic and almost periodic semiflows, basic reproduction ratios, traveling waves, and global analysis of prototypical population models in ecology and epidemiology. Research mathematicians working with nonlinear dynamics, particularly those interested in applications to biology, will find this book useful. It may also be used as a textbook or as supplementary reading for a graduate special topics course on the theory and applications of dynamical systems. Dr. Xiao-Qiang Zhao is a University Research Professor at Memorial University of Newfoundland, Canada. His main research interests involve applied...
Fluid dynamics theory, computation, and numerical simulation
Pozrikidis, C
2017-01-01
This book provides an accessible introduction to the basic theory of fluid mechanics and computational fluid dynamics (CFD) from a modern perspective that unifies theory and numerical computation. Methods of scientific computing are introduced alongside with theoretical analysis and MATLAB® codes are presented and discussed for a broad range of topics: from interfacial shapes in hydrostatics, to vortex dynamics, to viscous flow, to turbulent flow, to panel methods for flow past airfoils. The third edition includes new topics, additional examples, solved and unsolved problems, and revised images. It adds more computational algorithms and MATLAB programs. It also incorporates discussion of the latest version of the fluid dynamics software library FDLIB, which is freely available online. FDLIB offers an extensive range of computer codes that demonstrate the implementation of elementary and advanced algorithms and provide an invaluable resource for research, teaching, classroom instruction, and self-study. This ...
Variational principles for stochastic fluid dynamics.
Holm, Darryl D
2015-04-08
This paper derives stochastic partial differential equations (SPDEs) for fluid dynamics from a stochastic variational principle (SVP). The paper proceeds by taking variations in the SVP to derive stochastic Stratonovich fluid equations; writing their Itô representation; and then investigating the properties of these stochastic fluid models in comparison with each other, and with the corresponding deterministic fluid models. The circulation properties of the stochastic Stratonovich fluid equations are found to closely mimic those of the deterministic ideal fluid models. As with deterministic ideal flows, motion along the stochastic Stratonovich paths also preserves the helicity of the vortex field lines in incompressible stochastic flows. However, these Stratonovich properties are not apparent in the equivalent Itô representation, because they are disguised by the quadratic covariation drift term arising in the Stratonovich to Itô transformation. This term is a geometric generalization of the quadratic covariation drift term already found for scalar densities in Stratonovich's famous 1966 paper. The paper also derives motion equations for two examples of stochastic geophysical fluid dynamics; namely, the Euler-Boussinesq and quasi-geostropic approximations.
Variational principles for stochastic fluid dynamics
Holm, Darryl D.
2015-01-01
This paper derives stochastic partial differential equations (SPDEs) for fluid dynamics from a stochastic variational principle (SVP). The paper proceeds by taking variations in the SVP to derive stochastic Stratonovich fluid equations; writing their Itô representation; and then investigating the properties of these stochastic fluid models in comparison with each other, and with the corresponding deterministic fluid models. The circulation properties of the stochastic Stratonovich fluid equations are found to closely mimic those of the deterministic ideal fluid models. As with deterministic ideal flows, motion along the stochastic Stratonovich paths also preserves the helicity of the vortex field lines in incompressible stochastic flows. However, these Stratonovich properties are not apparent in the equivalent Itô representation, because they are disguised by the quadratic covariation drift term arising in the Stratonovich to Itô transformation. This term is a geometric generalization of the quadratic covariation drift term already found for scalar densities in Stratonovich's famous 1966 paper. The paper also derives motion equations for two examples of stochastic geophysical fluid dynamics; namely, the Euler–Boussinesq and quasi-geostropic approximations. PMID:27547083
Radioimmunoassay of penicilloyl groups in biological fluids
International Nuclear Information System (INIS)
Wal, J-M.; Bories, G.
1975-01-01
Penicilloyl-protein conjugates may be formed in man or animals after therapeutic treatment but cannot be detected by the classical microbiological assay methods used for penicillin. Allergies have been noted in consumers of products coming from animals treated with penicillin (milk particularly). Although these compounds present a risk to public health, they passed unnoticed through hygienic food inspection. Therefore a specific and sensitive method was devised for the assay of these derivatives in biological fluids where they can be present in trace amounts. An iodine-125 labelled conjugate has been prepared. Already usable for the detection of antipenicilloyl antibodies in sera of penicillin allergic patients, it has been used for the development of a radioimmunoassay of penicilloyl groups. Assay is done directly on milk, urine and serum without previous extraction and with a detection limit of a few ppb. It permits a rapid, specific and easy to handle determination in the sera of hospital patients as well as in the inspection of animal products at the slaughter house and at the dairy
New derivation of relativistic dissipative fluid dynamics
International Nuclear Information System (INIS)
Jaiswal, Amaresh; Bhalerao, Rajeev S.; Pal, Subrata
2012-01-01
Relativistic dissipative hydrodynamics has been quite successful in explaining the spectra and azimuthal anisotropy of particles produced in heavy-ion collisions at the RHIC and recently at the LHC. The first-order dissipative fluid dynamics or the relativistic Navier-Stokes (NS) theory involves parabolic differential equations and suffers from a causality and instability. The second-order or Israel-Stewart (IS) theory with its hyperbolic equations restores causality but may not guarantee stability. The correct formulation of relativistic viscous fluid dynamics is far from settled and is under intense investigation
Challenges in fluid dynamics a new approach
Zeytounian, R Kh
2017-01-01
This monograph presents a synopsis of fluid dynamics based on the personal scientific experience of the author who has contributed immensely to the field. The interested reader will also benefit from the general historical context in which the material is presented in the book. The book covers a wide range of relevant topics of the field, and the main tool being rational asymptotic modelling (RAM) approach. The target audience primarily comprises experts in the field of fluid dynamics, but the book may also be beneficial for graduate students.
Finite Element Framework for Computational Fluid Dynamics in FEBio.
Ateshian, Gerard A; Shim, Jay J; Maas, Steve A; Weiss, Jeffrey A
2018-02-01
The mechanics of biological fluids is an important topic in biomechanics, often requiring the use of computational tools to analyze problems with realistic geometries and material properties. This study describes the formulation and implementation of a finite element framework for computational fluid dynamics (CFD) in FEBio, a free software designed to meet the computational needs of the biomechanics and biophysics communities. This formulation models nearly incompressible flow with a compressible isothermal formulation that uses a physically realistic value for the fluid bulk modulus. It employs fluid velocity and dilatation as essential variables: The virtual work integral enforces the balance of linear momentum and the kinematic constraint between fluid velocity and dilatation, while fluid density varies with dilatation as prescribed by the axiom of mass balance. Using this approach, equal-order interpolations may be used for both essential variables over each element, contrary to traditional mixed formulations that must explicitly satisfy the inf-sup condition. The formulation accommodates Newtonian and non-Newtonian viscous responses as well as inviscid fluids. The efficiency of numerical solutions is enhanced using Broyden's quasi-Newton method. The results of finite element simulations were verified using well-documented benchmark problems as well as comparisons with other free and commercial codes. These analyses demonstrated that the novel formulation introduced in FEBio could successfully reproduce the results of other codes. The analogy between this CFD formulation and standard finite element formulations for solid mechanics makes it suitable for future extension to fluid-structure interactions (FSIs).
Computational fluid dynamics incompressible turbulent flows
Kajishima, Takeo
2017-01-01
This textbook presents numerical solution techniques for incompressible turbulent flows that occur in a variety of scientific and engineering settings including aerodynamics of ground-based vehicles and low-speed aircraft, fluid flows in energy systems, atmospheric flows, and biological flows. This book encompasses fluid mechanics, partial differential equations, numerical methods, and turbulence models, and emphasizes the foundation on how the governing partial differential equations for incompressible fluid flow can be solved numerically in an accurate and efficient manner. Extensive discussions on incompressible flow solvers and turbulence modeling are also offered. This text is an ideal instructional resource and reference for students, research scientists, and professional engineers interested in analyzing fluid flows using numerical simulations for fundamental research and industrial applications. • Introduces CFD techniques for incompressible flow and turbulence with a comprehensive approach; • Enr...
Fluid models and simulations of biological cell phenomena
Greenspan, H. P.
1982-01-01
The dynamics of coated droplets are examined within the context of biofluids. Of specific interest is the manner in which the shape of a droplet, the motion within it as well as that of aggregates of droplets can be controlled by the modulation of surface properties and the extent to which such fluid phenomena are an intrinsic part of cellular processes. From the standpoint of biology, an objective is to elucidate some of the general dynamical features that affect the disposition of an entire cell, cell colonies and tissues. Conventionally averaged field variables of continuum mechanics are used to describe the overall global effects which result from the myriad of small scale molecular interactions. An attempt is made to establish cause and effect relationships from correct dynamical laws of motion rather than by what may have been unnecessary invocation of metabolic or life processes. Several topics are discussed where there are strong analogies droplets and cells including: encapsulated droplets/cell membranes; droplet shape/cell shape; adhesion and spread of a droplet/cell motility and adhesion; and oams and multiphase flows/cell aggregates and tissues. Evidence is presented to show that certain concepts of continuum theory such as suface tension, surface free energy, contact angle, bending moments, etc. are relevant and applicable to the study of cell biology.
Vortex dynamics in plasmas and fluids
International Nuclear Information System (INIS)
Rasmussen, J.J.; Lynov, J.P.; Hesthaven, J.S.; Sutyrin, G.G.
1994-01-01
The existence and dynamics of vortical structures in both homogeneous and inhomogeneous systems will be discussed. In particular the dynamics of monopolar and dipolar vortices in a plasma with nonuniform density and in a rotating fluid with varying Coriolis force is described. The role of vortical structures in connection with electrostatic plasma turbulence and the associated cross-field plasma transport will also be addressed. (Author)
Education and research in fluid dynamics
López González-Nieto, P.; Redondo, J. M.; Cano, J. L.
2009-04-01
Fluid dynamics constitutes an essential subject for engineering, since auronautic engineers (airship flights in PBL, flight processes), industrial engineers (fluid transportation), naval engineers (ship/vessel building) up to agricultural engineers (influence of the weather conditions on crops/farming). All the above-mentioned examples possess a high social and economic impact on mankind. Therefore, the fluid dynamics education of engineers is very important, and, at the same time, this subject gives us an interesting methodology based on a cycle relation among theory, experiments and numerical simulation. The study of turbulent plumes -a very important convective flow- is a good example because their theoretical governing equations are simple; it is possible to make experimental plumes in an aesy way and to carry out the corresponding numerical simulatons to verify experimental and theoretical results. Moreover, it is possible to get all these aims in the educational system (engineering schools or institutions) using a basic laboratory and the "Modellus" software.
Fluid dynamics in porous media with Sailfish
International Nuclear Information System (INIS)
Coelho, Rodrigo C V; Neumann, Rodrigo F
2016-01-01
In this work we show the application of Sailfish to the study of fluid dynamics in porous media. Sailfish is an open-source software based on the lattice-Boltzmann method. This application of computational fluid dynamics is of particular interest to the oil and gas industry and the subject could be a starting point for an undergraduate or graduate student in physics or engineering. We built artificial samples of porous media with different porosities and used Sailfish to simulate the fluid flow through them in order to calculate their permeability and tortuosity. We also present a simple way to obtain the specific superficial area of porous media using Python libraries. To contextualise these concepts, we analyse the applicability of the Kozeny–Carman equation, which is a well-known permeability–porosity relation, to our artificial samples. (paper)
Fluid dynamics in porous media with Sailfish
Coelho, Rodrigo C. V.; Neumann, Rodrigo F.
2016-09-01
In this work we show the application of Sailfish to the study of fluid dynamics in porous media. Sailfish is an open-source software based on the lattice-Boltzmann method. This application of computational fluid dynamics is of particular interest to the oil and gas industry and the subject could be a starting point for an undergraduate or graduate student in physics or engineering. We built artificial samples of porous media with different porosities and used Sailfish to simulate the fluid flow through them in order to calculate their permeability and tortuosity. We also present a simple way to obtain the specific superficial area of porous media using Python libraries. To contextualise these concepts, we analyse the applicability of the Kozeny-Carman equation, which is a well-known permeability-porosity relation, to our artificial samples.
Computational Fluid Dynamics in Ventilation Design
DEFF Research Database (Denmark)
Nielsen, Peter V.
2008-01-01
This paper is based on the new REHVA Guidebook Computational Fluid Dynamics in Ventilation Design (Nielsen et al. 2007) written by Peter V. Nielsen, Francis(Nielsen 2007) written by Peter V. Nielsen, Francis Allard, Hazim B. Awbi, Lars Davidson and Alois Schälin. The guidebook is made for people...
Syringe irrigation: blending endodontics and fluid dynamics
Boutsioukis, C.; van der Sluis, L.W.M.; Basrani, B.
2015-01-01
Syringe irrigation remains a widely used irrigant delivery method during root canal treatment. An interdisciplinary approach involving well-established methods from the field of fluid dynamics can provide new insights into the mechanisms involved in cleaning and disinfection of the root canal system
Fluid dynamics via examples and solutions
Nazarenko, Sergey
2014-01-01
"This is an excellent book for fluid dynamics students. It gives a good overview of the theory through a large set of worthy example problems. After many classical textbooks on the subject, there is finally one with solved exercises. I fully appreciate the selection of topics."-Professor Miguel Onorato, Physics Department, University of Torino.
Computational fluid dynamics in greenhouses: A review
African Journals Online (AJOL)
use
2011-12-05
Dec 5, 2011 ... Computational fluid dynamics is a tool that has been used in recent years to develop numerical models that improve our understanding of the interaction of variables that make up the climate inside greenhouses. In the past five years, more realistic studies have appeared due mainly to the development of ...
Modern Fluid Dynamics Intermediate Theory and Applications
Kleinstreuer, Clement
2010-01-01
Features pedagogical elements that include consistent 50/50 physics-mathematics approach when introducing material, illustrating concepts, showing flow visualizations, and solving problems. This title intends to help serious undergraduate student solve basic fluid dynamics problems independently, and suggest system design improvements
Engineering applications of computational fluid dynamics
Awang, Mokhtar
2015-01-01
This volume presents the results of Computational Fluid Dynamics (CFD) analysis that can be used for conceptual studies of product design, detail product development, process troubleshooting. It demonstrates the benefit of CFD modeling as a cost saving, timely, safe and easy to scale-up methodology.
Effects of fluid dynamics on cleaning efficacy of supercritical fluids
Energy Technology Data Exchange (ETDEWEB)
Phelps, M.R.; Willcox, W.A.; Silva, L.J.; Butner, R.S.
1993-03-01
Pacific Northwest Laboratory (PNL) and Boeing Aerospace Company are developing a process to clean metal parts using a supercritical solvent. This work is part of an effort to address issues inhibiting the rapid commercialization of Supercritical Fluid Parts Cleaning (SFPC). PNL assembled a SFPC test stand to observe the relationship between the fluid dynamics of the system and the mass transfer of a contaminant from the surface of a contaminated metal coupon into the bulk fluid. The bench-scale test stand consists of a Berty'' autoclave modified for these tests and supporting hardware to achieve supercritical fluids parts cleaning. Three separate sets of tests were conducted using supercritical carbon dioxide. For the first two tests, a single stainless steel coupon was cleaned with organic solvents to remove surface residue, doped with a single contaminant, and then cleaned in the SFPC test stand. Contaminants studied were Dow Corning 200 fluid (dimethylpolysiloxane) and Castle/Sybron X-448 High-temperature Oil (a polybutane/mineral oil mixture). A set of 5-minute cleaning runs was conducted for each dopant at various autoclave impeller speeds. Test results from the first two sets of experiments indicate that precision cleaning for difficult-to-remove contaminants can be dramatically improved by introducing and increasing turbulence within the system. Metal coupons that had been previously doped with aircraft oil were used in a third set of tests. The coupons were placed in the SFPC test stand and subjected to different temperatures, pressures, and run times at a constant impeller speed. The cleanliness of each part was measured by Optically Stimulated Electron Emission. The third set of tests show that levels of cleanliness attained with supercritical carbon dioxide compare favorably with solvent and aqueous cleaning levels.
Effects of fluid dynamics on cleaning efficacy of supercritical fluids
Energy Technology Data Exchange (ETDEWEB)
Phelps, M.R.; Willcox, W.A.; Silva, L.J.; Butner, R.S.
1993-03-01
Pacific Northwest Laboratory (PNL) and Boeing Aerospace Company are developing a process to clean metal parts using a supercritical solvent. This work is part of an effort to address issues inhibiting the rapid commercialization of Supercritical Fluid Parts Cleaning (SFPC). PNL assembled a SFPC test stand to observe the relationship between the fluid dynamics of the system and the mass transfer of a contaminant from the surface of a contaminated metal coupon into the bulk fluid. The bench-scale test stand consists of a ``Berty`` autoclave modified for these tests and supporting hardware to achieve supercritical fluids parts cleaning. Three separate sets of tests were conducted using supercritical carbon dioxide. For the first two tests, a single stainless steel coupon was cleaned with organic solvents to remove surface residue, doped with a single contaminant, and then cleaned in the SFPC test stand. Contaminants studied were Dow Corning 200 fluid (dimethylpolysiloxane) and Castle/Sybron X-448 High-temperature Oil (a polybutane/mineral oil mixture). A set of 5-minute cleaning runs was conducted for each dopant at various autoclave impeller speeds. Test results from the first two sets of experiments indicate that precision cleaning for difficult-to-remove contaminants can be dramatically improved by introducing and increasing turbulence within the system. Metal coupons that had been previously doped with aircraft oil were used in a third set of tests. The coupons were placed in the SFPC test stand and subjected to different temperatures, pressures, and run times at a constant impeller speed. The cleanliness of each part was measured by Optically Stimulated Electron Emission. The third set of tests show that levels of cleanliness attained with supercritical carbon dioxide compare favorably with solvent and aqueous cleaning levels.
Modeling Tools Predict Flow in Fluid Dynamics
2010-01-01
"Because rocket engines operate under extreme temperature and pressure, they present a unique challenge to designers who must test and simulate the technology. To this end, CRAFT Tech Inc., of Pipersville, Pennsylvania, won Small Business Innovation Research (SBIR) contracts from Marshall Space Flight Center to develop software to simulate cryogenic fluid flows and related phenomena. CRAFT Tech enhanced its CRUNCH CFD (computational fluid dynamics) software to simulate phenomena in various liquid propulsion components and systems. Today, both government and industry clients in the aerospace, utilities, and petrochemical industries use the software for analyzing existing systems as well as designing new ones."
Methods for analysis of fluoroquinolones in biological fluids
Methods for analysis of 10 selected fluoroquinolone antibiotics in biological fluids are reviewed. Approaches for sample preparation, detection methods, limits of detection and quantitation and recovery information are provided for both single analyte and multi-analyte fluoroquinolone methods....
Well-posedness of problems in fluid dynamics (a fluid-dynamical point of view)
International Nuclear Information System (INIS)
Zeytounian, R Kh
1999-01-01
The proofs of the existence, uniqueness, smoothness, and stability of solutions of problems in fluid dynamics are needed to give meaning to the equations and corresponding initial and boundary conditions that govern these problems. For any arbitrary reasonable choice of a class of admissible initial data, a problem in fluid dynamics must be well posed (in the Hadamard sense). This means that (a) the problem has a solution for any initial data in this class, (b) this solution is unique for any initial conditions, (c) the solution depends continuously on the initial data. In this paper we give a survey of some aspects of problems on well-posedness from the point of view of fluid dynamics itself; these problems form a very difficult and at the same time important part of fluid mechanics
The fluid dynamics of human birth
Lehn, Andrea; Leftwich, Megan C.
2012-11-01
This study investigates the fluid dynamics associated with the human birth process. Specifically, we investigate the role of the viscosity of the amniotic fluid in transferring force from the contracting uterus to the fetus during delivery. This experimental work uses an approximate uterus and dilated cervix-fabricated with liquid latex-filled with a fluid of known viscosity and an oblong solid fetus. The force required to extract the fetus is recorded for several values of amniotic viscosity. The study looks at both pull-out force values (where the fetus is pulled from outside the uterus) and push-out force values (where pressure in the experimental uterus is used to remove the fetus). In addition to the viscosity study, we also investigate the increased force required to deliver an offset fetus by tilting the major axis of the oblong fetus and repeating the pull-and push-out experiments. This study will provide knowledge about the fundamental fluid dynamic processes involved in human birth.
Cardiac fluid dynamics meets deformation imaging.
Dal Ferro, Matteo; Stolfo, Davide; De Paris, Valerio; Lesizza, Pierluigi; Korcova, Renata; Collia, Dario; Tonti, Giovanni; Sinagra, Gianfranco; Pedrizzetti, Gianni
2018-02-20
Cardiac function is about creating and sustaining blood in motion. This is achieved through a proper sequence of myocardial deformation whose final goal is that of creating flow. Deformation imaging provided valuable contributions to understanding cardiac mechanics; more recently, several studies evidenced the existence of an intimate relationship between cardiac function and intra-ventricular fluid dynamics. This paper summarizes the recent advances in cardiac flow evaluations, highlighting its relationship with heart wall mechanics assessed through the newest techniques of deformation imaging and finally providing an opinion of the most promising clinical perspectives of this emerging field. It will be shown how fluid dynamics can integrate volumetric and deformation assessments to provide a further level of knowledge of cardiac mechanics.
Fluid Dynamics of Pressurized, Entrained Coal Gasifiers
International Nuclear Information System (INIS)
1997-01-01
Pressurized, entrained gasification is a promising new technology for the clean and efficient combustion of coal. Its principle is to operate a coal gasifier at a high inlet gas velocity to increase the inflow of reactants, and at an elevated pressure to raise the overall efficiency of the process. Unfortunately, because of the extraordinary difficulties involved in performing measurements in hot, pressurized, high-velocity pilot plants, its fluid dynamics are largely unknown. Thus the designer cannot predict with certainty crucial phenomena like erosion, heat transfer and solid capture. In this context, we are conducting a study of the fluid dynamics of Pressurized Entrained Coal Gasifiers (PECGs). The idea is to simulate the flows in generic industrial PECGs using dimensional similitude. To this end, we employ a unique entrained gas-solid flow facility with the flexibility to recycle--rather than discard--gases other than air. By matching five dimensionless parameters, suspensions in mixtures of helium, carbon dioxide and sulfur hexafluoride simulate the effects of pressure and scale-upon the fluid dynamics of PECGs. Because it operates under cold, atmospheric conditions, the laboratory facility is ideal for detailed measurements
Evolutionary Dynamics of Biological Auctions
Chatterjee, Krishnendu; Reiter, Johannes G.; Nowak, Martin A.
2011-01-01
Many scenarios in the living world, where individual organisms compete for winning positions (or resources), have properties of auctions. Here we study the evolution of bids in biological auctions. For each auction n individuals are drawn at random from a population of size N. Each individual makes a bid which entails a cost. The winner obtains a benefit of a certain value. Costs and benefits are translated into reproductive success (fitness). Therefore, successful bidding strategies spread in the population. We compare two types of auctions. In “biological all-pay auctions” the costs are the bid for every participating individual. In “biological second price all-pay auctions” the cost for everyone other than the winner is the bid, but the cost for the winner is the second highest bid. Second price all-pay auctions are generalizations of the “war of attrition” introduced by Maynard Smith. We study evolutionary dynamics in both types of auctions. We calculate pairwise invasion plots and evolutionarily stable distributions over the continuous strategy space. We find that the average bid in second price all-pay auctions is higher than in all-pay auctions, but the average cost for the winner is similar in both auctions. In both cases the average bid is a declining function of the number of participants, n. The more individuals participate in an auction the smaller is the chance of winning, and thus expensive bids must be avoided. PMID:22120126
The fluid dynamics of the chocolate fountain
Townsend, Adam K.; Wilson, Helen J.
2016-01-01
We consider the fluid dynamics of the chocolate fountain. Molten chocolate is a mildly shear-thinning non-Newtonian fluid. Dividing the flow into three main domains—the pumped flow up the centre, the film flow over each dome, and the freely falling curtain flow between the domes—we generate a wide-ranging study of Newtonian and non-Newtonian fluid mechanics. The central pumped flow is a benchmark to elucidate the effects of shear-thinning. The dome flow can be modelled as a thin-film flow with the leading-order effects being a simple balance of gravity and viscosity. Finally, the curtain flow is analytically intractable but is related to the existing theory of water bells (both inviscid and viscous). In pipe flow, Newtonian fluids exhibit a parabolic velocity profile; shear-thinning makes the profile more blunted. In thin-film flow over the dome, gravitational and viscous effects balance and the dome shape is not important beyond the local slope. We find that the chocolate thins and slows down as it travels down the dome. Finally, in the curtain flow, we predict the shape of the falling sheet for an inviscid fluid, and compare this with the literature to predict the shape for a viscous fluid, having shown that viscous forces are too great to ignore. We also find that the primary effect driving the shape of the curtain (which falls inwards towards the axis of the fountain) is surface tension. We find that the three domains provide excellent introductions to non-Newtonian mechanics, the important mathematical technique of scaling, and how to manipulate existing data to make our own predictions. We also find that the topic generates interest among the public in our engagement work.
The fluid dynamics of the chocolate fountain
International Nuclear Information System (INIS)
Townsend, Adam K; Wilson, Helen J
2016-01-01
We consider the fluid dynamics of the chocolate fountain. Molten chocolate is a mildly shear-thinning non-Newtonian fluid. Dividing the flow into three main domains—the pumped flow up the centre, the film flow over each dome, and the freely falling curtain flow between the domes—we generate a wide-ranging study of Newtonian and non-Newtonian fluid mechanics. The central pumped flow is a benchmark to elucidate the effects of shear-thinning. The dome flow can be modelled as a thin-film flow with the leading-order effects being a simple balance of gravity and viscosity. Finally, the curtain flow is analytically intractable but is related to the existing theory of water bells (both inviscid and viscous). In pipe flow, Newtonian fluids exhibit a parabolic velocity profile; shear-thinning makes the profile more blunted. In thin-film flow over the dome, gravitational and viscous effects balance and the dome shape is not important beyond the local slope. We find that the chocolate thins and slows down as it travels down the dome. Finally, in the curtain flow, we predict the shape of the falling sheet for an inviscid fluid, and compare this with the literature to predict the shape for a viscous fluid, having shown that viscous forces are too great to ignore. We also find that the primary effect driving the shape of the curtain (which falls inwards towards the axis of the fountain) is surface tension. We find that the three domains provide excellent introductions to non-Newtonian mechanics, the important mathematical technique of scaling, and how to manipulate existing data to make our own predictions. We also find that the topic generates interest among the public in our engagement work. (paper)
Dynamics of fluid mixing in separated flows
Leder, A.
1991-05-01
Separated flows at high Re (>103) are highly turbulent. In some situations the turbulence generation and mixing processes associated with flow separation are desirable, e.g., in heat exchangers or in many chemical engineering applications. In others, e.g., stalled airfoils, separation must be avoided as it causes loss in pressure and kinetic energy. To control the phenomenon effectively, physical mechanisms of flow separation and related aspects, such as the growth of flow instabilities in shear layers, the process of vortex formation, and the dynamics of fluid mixing in recirculating flow regions, must be understood. In many cases numerical procedures, e.g., Navier-Stokes calculations including k-ɛ turbulence modeling, fail to predict real physical mechanisms in separated flows.1,2 Separated flows in the lee of bluff bodies have been studied for many years.3,4 However, accurate measurements of the magnitude and direction of velocities and the magnitude of the terms of the Reynolds stress tensor have been restricted by the unsuitability of the hot-wire anemometer in recirculating flows. The development of the pulsed-wire anemometer, flying hot-wire anemometer, and laser-Doppler anemometry (LDA) allows more reliable measurements also in turbulent separated flows.5-8 The aim of this paper is to investigate the dynamics of undisturbed fluid mixing in separated regions of 2-D, incompressible flows with visualization techniques and LDA. Measurements were performed with a vertical flat plate model, mounted in a closed-circuit wind tunnel at low blockage ratio. Because of the noninvasive character, optical techniques like LDA are more suitable to analyze complex fluid motions than pulsed-wire and flying-wire anemometry. The LDA system used to investigate turbulent flow structures consists of a two-channel version operating in backscatter mode and a specifically developed phase detector to extract phase-averaged information from recorded measurement ensembles.9 Endplates
Computational Fluid Dynamics - Applications in Manufacturing Processes
Beninati, Maria Laura; Kathol, Austin; Ziemian, Constance
2012-11-01
A new Computational Fluid Dynamics (CFD) exercise has been developed for the undergraduate introductory fluid mechanics course at Bucknell University. The goal is to develop a computational exercise that students complete which links the manufacturing processes course and the concurrent fluid mechanics course in a way that reinforces the concepts in both. In general, CFD is used as a tool to increase student understanding of the fundamentals in a virtual world. A ``learning factory,'' which is currently in development at Bucknell seeks to use the laboratory as a means to link courses that previously seemed to have little correlation at first glance. A large part of the manufacturing processes course is a project using an injection molding machine. The flow of pressurized molten polyurethane into the mold cavity can also be an example of fluid motion (a jet of liquid hitting a plate) that is applied in manufacturing. The students will run a CFD process that captures this flow using their virtual mold created with a graphics package, such as SolidWorks. The laboratory structure is currently being implemented and analyzed as a part of the ``learning factory''. Lastly, a survey taken before and after the CFD exercise demonstrate a better understanding of both the CFD and manufacturing process.
Dissipative dynamics of fluid lipid membranes enriched in cholesterol.
Arriaga, Laura R; Rodríguez-García, Ruddi; Moleiro, Lara H; Prévost, Sylvain; López-Montero, Iván; Hellweg, Thomas; Monroy, Francisco
2017-09-01
Cholesterol is an intriguing component of fluid lipid membranes: It makes them stiffer but also more fluid. Despite the enormous biological significance of this complex dynamical behavior, which blends aspects of membrane elasticity with viscous friction, their mechanical bases remain however poorly understood. Here, we show that the incorporation of physiologically relevant contents of cholesterol in model fluid membranes produces a fourfold increase in the membrane bending modulus. However, the increase in the compression rigidity that we measure is only twofold; this indicates that cholesterol increases coupling between the two membrane leaflets. In addition, we show that although cholesterol makes each membrane leaflet more fluid, it increases the friction between the membrane leaflets. This dissipative dynamics causes opposite but advantageous effects over different membrane motions: It allows the membrane to rearrange quickly in the lateral dimension, and to simultaneously dissipate out-of-plane stresses through friction between the two membrane leaflets. Moreover, our results provide a clear correlation between coupling and friction of membrane leaflets. Furthermore, we show that these rigid membranes are optimal to resist slow deformations with minimum energy dissipation; their optimized stability might be exploited to design soft technological microsystems with an encoded mechanics, vesicles or capsules for instance, useful beyond classical applications as model biophysical systems. Copyright © 2017 Elsevier B.V. All rights reserved.
Topological fluid dynamics of interfacial flows
DEFF Research Database (Denmark)
Brøns, Morten
1994-01-01
The topological description of flows in the vicinity of a solid boundary, that is familiar from the aerodynamics literature, has recently been extended to the case of flow at a liquid–gas interface or a free surface by Lugt [Phys. Fluids 30, 3647 (1987)]. Lugt's work is revisited in a more general...... setting, including nonconstant curvature of the interface and gradients of surface tension, using tools of modern nonlinear dynamics. Bifurcations of the flow pattern occur at degenerate configurations. Using the theory of unfolding, this paper gives a complete description of the bifurcations that depend...... on terms up to the second order. The general theory of this paper is applied to the topology of streamlines during the breaking of a wave and to the flow below a stagnant surface film. Physics of Fluids is copyrighted by The American Institute of Physics....
Direct modeling for computational fluid dynamics
Xu, Kun
2015-06-01
All fluid dynamic equations are valid under their modeling scales, such as the particle mean free path and mean collision time scale of the Boltzmann equation and the hydrodynamic scale of the Navier-Stokes (NS) equations. The current computational fluid dynamics (CFD) focuses on the numerical solution of partial differential equations (PDEs), and its aim is to get the accurate solution of these governing equations. Under such a CFD practice, it is hard to develop a unified scheme that covers flow physics from kinetic to hydrodynamic scales continuously because there is no such governing equation which could make a smooth transition from the Boltzmann to the NS modeling. The study of fluid dynamics needs to go beyond the traditional numerical partial differential equations. The emerging engineering applications, such as air-vehicle design for near-space flight and flow and heat transfer in micro-devices, do require further expansion of the concept of gas dynamics to a larger domain of physical reality, rather than the traditional distinguishable governing equations. At the current stage, the non-equilibrium flow physics has not yet been well explored or clearly understood due to the lack of appropriate tools. Unfortunately, under the current numerical PDE approach, it is hard to develop such a meaningful tool due to the absence of valid PDEs. In order to construct multiscale and multiphysics simulation methods similar to the modeling process of constructing the Boltzmann or the NS governing equations, the development of a numerical algorithm should be based on the first principle of physical modeling. In this paper, instead of following the traditional numerical PDE path, we introduce direct modeling as a principle for CFD algorithm development. Since all computations are conducted in a discretized space with limited cell resolution, the flow physics to be modeled has to be done in the mesh size and time step scales. Here, the CFD is more or less a direct
Three-Dimensional Computational Fluid Dynamics
Energy Technology Data Exchange (ETDEWEB)
Haworth, D.C.; O' Rourke, P.J.; Ranganathan, R.
1998-09-01
Computational fluid dynamics (CFD) is one discipline falling under the broad heading of computer-aided engineering (CAE). CAE, together with computer-aided design (CAD) and computer-aided manufacturing (CAM), comprise a mathematical-based approach to engineering product and process design, analysis and fabrication. In this overview of CFD for the design engineer, our purposes are three-fold: (1) to define the scope of CFD and motivate its utility for engineering, (2) to provide a basic technical foundation for CFD, and (3) to convey how CFD is incorporated into engineering product and process design.
Computational Fluid Dynamics Technology for Hypersonic Applications
Gnoffo, Peter A.
2003-01-01
Several current challenges in computational fluid dynamics and aerothermodynamics for hypersonic vehicle applications are discussed. Example simulations are presented from code validation and code benchmarking efforts to illustrate capabilities and limitations. Opportunities to advance the state-of-art in algorithms, grid generation and adaptation, and code validation are identified. Highlights of diverse efforts to address these challenges are then discussed. One such effort to re-engineer and synthesize the existing analysis capability in LAURA, VULCAN, and FUN3D will provide context for these discussions. The critical (and evolving) role of agile software engineering practice in the capability enhancement process is also noted.
Computational fluid dynamics a practical approach
Tu, Jiyuan; Liu, Chaoqun
2018-01-01
Computational Fluid Dynamics: A Practical Approach, Third Edition, is an introduction to CFD fundamentals and commercial CFD software to solve engineering problems. The book is designed for a wide variety of engineering students new to CFD, and for practicing engineers learning CFD for the first time. Combining an appropriate level of mathematical background, worked examples, computer screen shots, and step-by-step processes, this book walks the reader through modeling and computing, as well as interpreting CFD results. This new edition has been updated throughout, with new content and improved figures, examples and problems.
Optics and Fluid Dynamics Department annual progress report for 1995
International Nuclear Information System (INIS)
Hanson, S.G.; Lading, L.; Lynov, J.P.; Skaarup, B.
1996-01-01
Research in the Optics and Fluid Dynamics Department has been performed within the following two programme areas: (1) optical diagnostics and information processing and (2) plasma and fluid dynamics. The optical activities are concentrated on optical materials, diagnostics and sensors. The plasma and fluid dynamics activities are concentrated on nonlinear dynamics in fluids, plasmas and optics as well as on plasma and fluid diagnostics. Scientific computing is an integral part of the work. The activities are supported by several EU programmes, including EURATOM, by research councils and by industry. A summary of the activities in 1995 is presented. (au) 36 ills., 166 refs
Optics and Fluid Dynamics Department annual progress report for 1995
Energy Technology Data Exchange (ETDEWEB)
Hanson, S.G.; Lading, L.; Lynov, J.P.; Skaarup, B. [eds.
1996-01-01
Research in the Optics and Fluid Dynamics Department has been performed within the following two programme areas: (1) optical diagnostics and information processing and (2) plasma and fluid dynamics. The optical activities are concentrated on optical materials, diagnostics and sensors. The plasma and fluid dynamics activities are concentrated on nonlinear dynamics in fluids, plasmas and optics as well as on plasma and fluid diagnostics. Scientific computing is an integral part of the work. The activities are supported by several EU programmes, including EURATOM, by research councils and by industry. A summary of the activities in 1995 is presented. (au) 36 ills., 166 refs.
Cerebrospinal fluid dynamics study in communicating hydrocephalus.
Ramesh, Vengalathur Ganesan; Narasimhan, Vidhya; Balasubramanian, Chandramouli
2017-01-01
Communicating hydrocephalus often poses a challenge in diagnosis and management decisions. The objective of this study is to measure the opening pressure (P o ), pressure volume index (PVI), and cerebrospinal fluid outflow resistance (R out ), in patients with communicating hydrocephalus using bolus lumbar injection method and to evaluate its diagnostic and prognostic value. The study was conducted in 50 patients with communicating hydrocephalus, including normal pressure hydrocephalus (NPH) (19), post-meningitic hydrocephalus (23) and post-traumatic hydrocephalus (8). An improvised bolus lumbar injection method [the Madras Institute of Neurology (MIN) method] was used. In the NPH Group, the CSF dynamics studies correlated well with the clinico-radiological classification. The prediction of shunt responsiveness by CSF dynamics studies correlated with good outcome in 87.5%. In the post-meningitic hydrocephalus group, the value of CSF dynamics studies in predicting patients needing shunt was 89.5%. The CSF dynamics studies detected patients who needed shunt earlier than clinical or radiological indications. In the post-traumatic hydrocephalus group, 62.5% of patients improved with the treatment based on CSF dynamics studies. The improvised bolus lumbar injection method (MIN method) is a very simple test with fairly reliable and reproducible results. Study of CSF dynamics is a valuable tool in communicating hydrocephalus for confirmation of diagnosis and predicting shunt responsiveness. This is the first time that the value of CSF dynamics has been studied in patients with post-meningitic hydrocephalus. It was also useful for early selection of cases for shunting and for identifying patients with atrophic ventriculomegaly, thereby avoiding unnecessary shunt.
Zonal methods and computational fluid dynamics
International Nuclear Information System (INIS)
Atta, E.H.
1985-01-01
Recent advances in developing numerical algorithms for solving fluid flow problems, and the continuing improvement in the speed and storage of large scale computers have made it feasible to compute the flow field about complex and realistic configurations. Current solution methods involve the use of a hierarchy of mathematical models ranging from the linearized potential equation to the Navier Stokes equations. Because of the increasing complexity of both the geometries and flowfields encountered in practical fluid flow simulation, there is a growing emphasis in computational fluid dynamics on the use of zonal methods. A zonal method is one that subdivides the total flow region into interconnected smaller regions or zones. The flow solutions in these zones are then patched together to establish the global flow field solution. Zonal methods are primarily used either to limit the complexity of the governing flow equations to a localized region or to alleviate the grid generation problems about geometrically complex and multicomponent configurations. This paper surveys the application of zonal methods for solving the flow field about two and three-dimensional configurations. Various factors affecting their accuracy and ease of implementation are also discussed. From the presented review it is concluded that zonal methods promise to be very effective for computing complex flowfields and configurations. Currently there are increasing efforts to improve their efficiency, versatility, and accuracy
Spontaneous canine hydrocephalus: cerebrospinal fluid dynamics1
Sahar, A.; Hochwald, G. M.; Kay, W. J.; Ransohoff, J.
1971-01-01
Cerebrospinal fluid dynamics were studied in 14 dogs with spontaneous hydrocephalus. In nine of the dogs aqueductal obstruction was observed and the remainder had a `communicating type' hydrocephalus. The major histological findings consisted of severe ependymal destruction, spongy changes in the periventricular white matter, increased density of capillaries in this area, and varying degrees of thickening, fibrosis, and fusion of the choroid villi. The formation and absorption of CSF were studied by perfusion of the cerebral ventricles. The rate of formation of CSF was found to decrease with perfusion pressure by Vf = 0·02595−0·00022 P ml./min (P = pressure in cm H2O). The absorption of spinal fluid was found to increase linearly with pressure by Va = 0·0165 + 0·00050 P. The various factors influencing the formation and absorption of the spinal fluid are discussed. The meaning and attainment of `arrest' of the hydrocephalic process in terms of the measured rates of CSF formation and absorption in these animals are considered. Images PMID:5571319
Dynamic simulation of an electrorheological fluid
International Nuclear Information System (INIS)
Bonnecaze, R.T.; Brady, J.F.
1992-01-01
A molecular-dynamics-like method is presented for the simulation of a suspension of dielectric particles in a nonconductive solvent forming an electrorheological fluid. The method accurately accounts for both hydrodynamic and electrostatic interparticle interactions from dilute volume fractions to closest packing for simultaneous shear and electric fields. The hydrodynamic interactions and rheology are determined with the Stokesian dynamics methodology, while the electrostatic interactions, in particular, the conservative electrostatic interparticle forces, are determined from the electrostatic energy of the suspension. The energy of the suspension is computed from the induced particle dipoles by a method previously developed [R. T. Bonnecaze and J. F. Brady, Proc. R. Soc. London, Ser. A 430, 285 (1990)]. Using the simulation, the dynamics can be directly correlated to the observed macroscopic rheology of the suspension for a range of the so-called Mason number, Ma, the ratio of viscous to electrostatic forces. The simulation is specifically applied to a monolayer of spherical particles of areal fraction 0.4 with a particle-to-fluid dielectric constant ratio of 4 for Ma=10 -4 to ∞. The effective viscosity of the suspension increases as Ma -1 or with the square of the electric field for small Ma and has a plateau value at large Ma, as is observed experimentally. This rheological behavior can be interpreted as Bingham plastic-like with a dynamic yield stress. The first normal stress difference is negative, and its magnitude increases as Ma -1 at small Ma with a large Ma plateau value of zero. In addition to the time averages of the rheology, the time traces of the viscosities are presented along with selected ''snapshots'' of the suspension microstructure
An application of quantum fluid dynamics
International Nuclear Information System (INIS)
Himi, M.; Fukushima, K.
1984-01-01
Hydrodynamics is often applied to quantum phenomena such as heavy-ion collisions. But here is should be noted that local equilibrium is not always realized in these collision processes and also the quantum effect is not fully taken into account in hydrodynamics. In this sense, a fluid-dynamical treatment of quantum many-body systems which does not presuppose local equilibrium is required. As an attempt in this direction, we derive simultaneous equations governing the motion of local variables such as the particle density rho(r,t) and velocity field v(r,t) by averaging a many-body wave function. The equations obtained will be shown to unify into a single nonlinear Schroedinger-type equation. Hence this is worthy of being called a quantum fluid dynamics (QFD). In deriving the QFD, we have employed the time-dependent Hartree-Fock and the generalized scaling approximation. Particularly, in order to attain self-containedness, we have assumed a certain relation which is valid in the case of the locally isotropic strain tensor. The introduction of anisotropy requires other local variables reflecting explicitly the deviation from local equilibrium and thus has been left as a future task. (orig.)
Modeling quantum fluid dynamics at nonzero temperatures
Berloff, Natalia G.; Brachet, Marc; Proukakis, Nick P.
2014-01-01
The detailed understanding of the intricate dynamics of quantum fluids, in particular in the rapidly growing subfield of quantum turbulence which elucidates the evolution of a vortex tangle in a superfluid, requires an in-depth understanding of the role of finite temperature in such systems. The Landau two-fluid model is the most successful hydrodynamical theory of superfluid helium, but by the nature of the scale separations it cannot give an adequate description of the processes involving vortex dynamics and interactions. In our contribution we introduce a framework based on a nonlinear classical-field equation that is mathematically identical to the Landau model and provides a mechanism for severing and coalescence of vortex lines, so that the questions related to the behavior of quantized vortices can be addressed self-consistently. The correct equation of state as well as nonlocality of interactions that leads to the existence of the roton minimum can also be introduced in such description. We review and apply the ideas developed for finite-temperature description of weakly interacting Bose gases as possible extensions and numerical refinements of the proposed method. We apply this method to elucidate the behavior of the vortices during expansion and contraction following the change in applied pressure. We show that at low temperatures, during the contraction of the vortex core as the negative pressure grows back to positive values, the vortex line density grows through a mechanism of vortex multiplication. This mechanism is suppressed at high temperatures. PMID:24704874
Automated Computational Fluid Dynamics Design With Shape Optimization, Phase II
National Aeronautics and Space Administration — Computational fluid dynamics (CFD) is used as an analysis tool to help the designer gain greater understanding of the fluid flow phenomena involved in the components...
Elementary derivation of Poisson structures for fluid dynamics and electrodynamics
International Nuclear Information System (INIS)
Kaufman, A.N.
1982-01-01
The canonical Poisson structure of the microscopic Lagrangian is used to deduce the noncanonical Poisson structure for the macroscopic Hamiltonian dynamics of a compressible neutral fluid and of fluid electrodynamics
Automated Computational Fluid Dynamics Design With Shape Optimization, Phase I
National Aeronautics and Space Administration — Computational fluid dynamics (CFD) is used as an analysis tool to help the designer gain greater understanding of the fluid flow phenomena involved in the components...
Applications of dynamical systems in biology and medicine
Radunskaya, Ami
2015-01-01
This volume highlights problems from a range of biological and medical applications that can be interpreted as questions about system behavior or control. Topics include drug resistance in cancer and malaria, biological fluid dynamics, auto-regulation in the kidney, anti-coagulation therapy, evolutionary diversification and photo-transduction. Mathematical techniques used to describe and investigate these biological and medical problems include ordinary, partial and stochastic differentiation equations, hybrid discrete-continuous approaches, as well as 2 and 3D numerical simulation. .
Computational fluid dynamics evaluation of excessive dynamic airway collapse.
Taherian, Shahab; Rahai, Hamid; Gomez, Bernardo; Waddington, Thomas; Mazdisnian, Farhad
2017-12-01
Excessive dynamic airway collapse, which is often caused by the collapse of the posterior membrane wall during exhalation, is often misdiagnosed with other diseases; stents can provide support for the collapsing airways. The standard pulmonary function tests do not necessarily show change in functional breathing condition for evaluation of these type of diseases. Flow characteristics through a patient's airways with excessive dynamic airway collapse have been numerically investigated. A stent was placed to support the collapsing airway and to improve breathing conditions. Computed tomography images of the patient's pre- and post-stenting were used for generating 3-Dimensional models of the airways, and were imported into a computational fluid dynamics software for simulation of realistic air flow behavior. Unsteady simulations of the inspiratory phase and expiratory phase were performed with patient-specific boundary conditions for pre- and post-intervention cases to investigate the effect of stent placement on flow characteristic and possible improvements. Results of post-stent condition show reduced pressure, velocity magnitude and wall shear stress during expiration. The variation in wall shear stress, velocity magnitude and pressure drop is negligible during inspiration. Although Spirometry tests do not show significant improvements, computational fluid dynamics results show significant improvements in pre- and post-treatment results, suggesting improvement in breathing condition. Copyright © 2017 Elsevier Ltd. All rights reserved.
Characterization of Nanoparticle Aggregation in Biologically Relevant Fluids
McEnnis, Kathleen; Lahann, Joerg
Nanoparticles (NPs) are often studied as drug delivery vehicles, but little is known about their behavior in blood once injected into animal models. If the NPs aggregate in blood, they will be shunted to the liver or spleen instead of reaching the intended target. The use of animals for these experiments is costly and raises ethical questions. Typically dynamic light scattering (DLS) is used to analyze aggregation behavior, but DLS cannot be used because the components of blood also scatter light. As an alternative, a method of analyzing NPs in biologically relevant fluids such as blood plasma has been developed using nanoparticle tracking analysis (NTA) with fluorescent filters. In this work, NTA was used to analyze the aggregation behavior of fluorescent polystyrene NPs with different surface modifications in blood plasma. It was expected that different surface chemistries on the particles will change the aggregation behavior. The effect of the surface modifications was investigated by quantifying the percentage of NPs in aggregates after addition to blood plasma. The use of this characterization method will allow for better understanding of particle behavior in the body, and potential problems, specifically aggregation, can be addressed before investing in in vivo studies.
The use of computers for instruction in fluid dynamics
Watson, Val
1987-01-01
Applications for computers which improve instruction in fluid dynamics are examined. Computers can be used to illustrate three-dimensional flow fields and simple fluid dynamics mechanisms, to solve fluid dynamics problems, and for electronic sketching. The usefulness of computer applications is limited by computer speed, memory, and software and the clarity and field of view of the projected display. Proposed advances in personal computers which will address these limitations are discussed. Long range applications for computers in education are considered.
Fluid and structural-dynamic piping system analysis
International Nuclear Information System (INIS)
Korthauer, H.J.; Lange, H.; Rychlik, G.
1993-01-01
By means of the fluid and structural-dynamic analyses conducted, the cooling system was qualified for all fluid-dynamic processes in normal and anomalous operation and in case of accidents. The boundary conditions assumed by us for the fluid and structural-dynamic analyses were confirmed by the forces and movements measured time for some operating conditions as a function of time. Expensive hardware measures such as additional supports or replacement of Tees were not necessary as we combined the fluid and structural-dynamic analyses and then demonstrated safety of the supports, connected components and some of the piping elements as such. (author)
CFDLIB05, Computational Fluid Dynamics Library
International Nuclear Information System (INIS)
Kashiwa, B.A.; Padial, N.T.; Rauenzahn, R.M.; VanderHeyden, W.B.
2007-01-01
1 - Description of program or function: CFDLib05 is the Los Alamos Computational Fluid Dynamics Library. This is a collection of hydro-codes using a common data structure and a common numerical method, for problems ranging from single-field, incompressible flow, to multi-species, multi-field, compressible flow. The data structure is multi-block, with a so-called structured grid in each block. The numerical method is a Finite-Volume scheme employing a state vector that is fully cell-centered. This means that the integral form of the conversation laws is solved on the physical domain that is represented by a mesh of control volumes. The typical control volume is an arbitrary quadrilateral in 2D and an arbitrary hexahedron in 3D. The Finite-Volume scheme is for time-unsteady flow and remains well coupled by means of time and space centered fluxes; if a steady state solution is required, the problem is integrated forward in time until the user is satisfied that the state is stationary. 2 - Methods: Cells-centered Implicit Continuous-fluid Eulerian (ICE) method
Artificial Intelligence In Computational Fluid Dynamics
Vogel, Alison Andrews
1991-01-01
Paper compares four first-generation artificial-intelligence (Al) software systems for computational fluid dynamics. Includes: Expert Cooling Fan Design System (EXFAN), PAN AIR Knowledge System (PAKS), grid-adaptation program MITOSIS, and Expert Zonal Grid Generation (EZGrid). Focuses on knowledge-based ("expert") software systems. Analyzes intended tasks, kinds of knowledge possessed, magnitude of effort required to codify knowledge, how quickly constructed, performances, and return on investment. On basis of comparison, concludes Al most successful when applied to well-formulated problems solved by classifying or selecting preenumerated solutions. In contrast, application of Al to poorly understood or poorly formulated problems generally results in long development time and large investment of effort, with no guarantee of success.
Variational approach to nuclear fluid dynamics
International Nuclear Information System (INIS)
Da Providencia, J.P.; Holzwarth, G.
1983-01-01
A variational derivation of a fluid-dynamical formalism for finite Fermi systems is presented which is based on a single determinant as variational function and does not exclude the possibility of transverse flow. Therefore the explicit specification of the time-odd part has to go beyond the local chi-approximation, while the time-even part is taken in the generalized scaling form. The necessary boundary conditions are derived from the variation of the lagrangian. The results confirm previous simplified approaches to a remarkable degree for quadrupole modes; for other multipolarities the deviations are much less than might be expected according to a sizeable change in the transverse sound speed. (orig.)
Computational fluid dynamics in brain aneurysms
Sforza, Daniel M.; Putman, Christopher M.; Cebral, Juan R.
2013-01-01
SUMMARY Because of its ability to deal with any geometry, image-based computational fluid dynamics (CFD) has been progressively used to investigate the role of hemodynamics in the underlying mechanisms governing the natural history of cerebral aneurysms. Despite great progress in methodological developments and many studies using patient-specific data, there are still significant controversies about the precise governing processes and divergent conclusions from apparently contradictory results. Sorting out these issues requires a global vision of the state of the art and a unified approach to solving this important scientific problem. Towards this end, this paper reviews the contributions made using patient-specific CFD models to further the understanding of these mechanisms, and highlights the great potential of patient-specific computational models for clinical use in the assessment of aneurysm rupture risk and patient management. PMID:25364852
Lectures series in computational fluid dynamics
International Nuclear Information System (INIS)
Thompson, K.W.
1987-08-01
The lecture notes cover the basic principles of computational fluid dynamics (CFD). They are oriented more toward practical applications than theory, and are intended to serve as a unified source for basic material in the CFD field as well as an introduction to more specialized topics in artificial viscosity and boundary conditions. Each chapter in the text is associated with a videotaped lecture. The basic properties of conservation laws, wave equations, and shock waves are described. The duality of the conservation law and wave representations is investigated, and shock waves are examined in some detail. Finite difference techniques are introduced for the solution of wave equations and conservation laws. Stability analysis for finite difference approximations are presented. A consistent description of artificial viscosity methods are provided. Finally, the problem of nonreflecting boundary conditions are treated
Domain decomposition algorithms and computational fluid dynamics
International Nuclear Information System (INIS)
Chan, T.F.
1988-01-01
In the past several years, domain decomposition has been a very popular topic, partly because of the potential of parallelization. Although numerous theories and algorithms have been developed for model elliptic problems, they are only recently starting to be tested on realistic applications. This paper investigates the application of some of these methods to two model problems in computational fluid dynamics: two-dimensional convection-diffusion problems and the incompressible driven cavity flow problem. The authors approach is the construction and analysis of efficient preconditioners for the interface operator to be used in the iterative solution of the interface solution. For the convection-diffusion problems, they discuss the effect of the convection term and its discretization on the performance of some of the preconditioners. For the driven cavity problem, they discuss the effectiveness of a class of boundary probe preconditioners
Fluid Dynamics with Cryogenic Fluid Transfer in Space Project
National Aeronautics and Space Administration — During chilldown of cryogenic fluid tanks and lines, the interface between the liquid and vapor rapidly changes. Understanding these rapid changes is key...
Dynamics of vortex structures in a stratified rotating fluid
Sokolovskiy, Mikhail A
2013-01-01
This book presents an extensive analysis of the dynamics of discrete and distributed baroclinic vortices in a multi-layer fluid that characterizes the main features of the large and mesoscales dynamics of the atmosphere and the ocean.
Fluid Dynamics of Human Phonation and Speech
Mittal, Rajat; Erath, Byron D.; Plesniak, Michael W.
2013-01-01
This article presents a review of the fluid dynamics, flow-structure interactions, and acoustics associated with human phonation and speech. Our voice is produced through the process of phonation in the larynx, and an improved understanding of the underlying physics of this process is essential to advancing the treatment of voice disorders. Insights into the physics of phonation and speech can also contribute to improved vocal training and the development of new speech compression and synthesis schemes. This article introduces the key biomechanical features of the laryngeal physiology, reviews the basic principles of voice production, and summarizes the progress made over the past half-century in understanding the flow physics of phonation and speech. Laryngeal pathologies, which significantly enhance the complexity of phonatory dynamics, are discussed. After a thorough examination of the state of the art in computational modeling and experimental investigations of phonatory biomechanics, we present a synopsis of the pacing issues in this arena and an outlook for research in this fascinating subject.
Computational fluid dynamics applications to improve crop production systems
Computational fluid dynamics (CFD), numerical analysis and simulation tools of fluid flow processes have emerged from the development stage and become nowadays a robust design tool. It is widely used to study various transport phenomena which involve fluid flow, heat and mass transfer, providing det...
Hajjarian, Zeinab; Nadkarni, Seemantini K.
2013-01-01
Biological fluids fulfill key functionalities such as hydrating, protecting, and nourishing cells and tissues in various organ systems. They are capable of these versatile tasks owing to their distinct structural and viscoelastic properties. Characterizing the viscoelastic properties of bio-fluids is of pivotal importance for monitoring the development of certain pathologies as well as engineering synthetic replacements. Laser Speckle Rheology (LSR) is a novel optical technology that enables mechanical evaluation of tissue. In LSR, a coherent laser beam illuminates the tissue and temporal speckle intensity fluctuations are analyzed to evaluate mechanical properties. The rate of temporal speckle fluctuations is, however, influenced by both optical and mechanical properties of tissue. Therefore, in this paper, we develop and validate an approach to estimate and compensate for the contributions of light scattering to speckle dynamics and demonstrate the capability of LSR for the accurate extraction of viscoelastic moduli in phantom samples and biological fluids of varying optical and mechanical properties. PMID:23705028
Quantum fluid dynamics within a relativistic density-functional framework
International Nuclear Information System (INIS)
Ghosh, S.K.; Deb, B.M.; Indian Inst. of Tech., Bombay. Group of Theoretical Studies)
1984-01-01
The authors explore certain interconnections between density-functional theory and quantum fluid dynamics of many-electron systems, in the relativistic domain, following the hydrodynamical approach for the one-particle Dirac equation. The spinor formulation is transformed into a tensor formulation, by defining a number of density functions. These lead to six 'classical' fluid dynamical equations, for a complete specification of the system. The various density functions and the hydrodynamical equations are physically interpreted. The relativistic hydrodynamics discussed, correspond to a 'spinning' fluid. The net many-electron fluid consists of components each of which is characterised by fluid dynamical quantities corresponding to each spinor. The net hydrodynamical quantities are obtained by summing over the occupied spinors. Thus, the earlier non-relativistic 'classical' picture of the many-electron fluid as a collection of individual fluid components is also valid in the relativistic domain. (author)
Dynamic modeling of oil boom failure using computational fluid dynamics
International Nuclear Information System (INIS)
Goodman, R. H.; Brown, H. M.; An, C. F.; Rowe, R. D.
1997-01-01
Oil retention boom failure mechanisms have been identified and studied using computational fluid dynamics (CFD), a powerful modeling tool combining fluid dynamics and mathematics with high speed computer technology. This study utilized a commercially available CFD package, 'Fluent', to simulate the oil-water flow around a barrier. 'Drainage failure', 'droplet entrainment' and 'critical accumulation' were modeled using this software. Flow characteristics were found to be different for different failure mechanisms. In the drainage failure process, the oil slick was compressed against the barrier until the slick was deep enough for the oil to leak under the barrier. During boom failure due to droplet entrainment, the oil-water interface of the oil slick was wavy and unstable. During boom failure due to critical accumulation, the oil remained a single mass and moved under the barrier readily. The most significant observation, however, was that flow patterns around barriers are modified by the presence of oil. Therefore, towing and wave-conformity tests of booms will not be meaningful unless such tests are conducted with oil present. 15 refs., 11 figs
Spinodal decomposition in multicomponent fluid mixtures: A molecular dynamics study
DEFF Research Database (Denmark)
Laradji, Mohamed; Mouritsen, Ole G.; Toxvaerd, Søren
1996-01-01
We have investigated the effect of the number p of components on the dynamics of phase separation in two-dimensional symmetric multicomponent fluids. In contrast to concentrated two-dimensional binary fluids, where the growth dynamics is controlled by the coupling of the velocity held to the order...
[Biologic tests for the diagnosis of amniotic fluid embolism].
Van Cortenbosch, B; Huel, C; Houfflin Debarge, V; Luton, D; Lambaudie, E; Porquet, D; Guibourdenche, J
2007-01-01
Amniotic fluid embolism is a rare, unpredictable and often lethal complication of pregnancy and childbirth. Because of its variable presentation, an early biologic test would help to establish the diagnosis. We investigated in maternal serum 4 components of amniotic fluid, i.e., alpha-fetoprotein (AFP), l'insuline like growth factor binding protein-1 (IGFBP-1), fetal fibronectin (fFN) and placental alpha1-microglobulin (PAMG-1). On the 6 cesareans controls involved, none of the makers increased after membranes section. PAMG-1 is unsuitable because its detection is always positive or doubtful even in the baseline. On the 7 cases suspected of amniotic fluid embolism, no detectable increase in any of those markers was noted in 3 cases, which is not in favour of this diagnosis. In the remaining cases, IGFBP-1 and fFN became detectable, confirming histological evidences of amniotic fluid embolism in 2 cases. The follow up of those markers in maternal blood confirmed the suspicion of amniotic fluid embolism at 21 wg in one case of ongoing pregnancy. These preliminary results point out the potential interest to assay maternal serum AFP, IGFBP-1 and fFN to confirm amniotic fluid embolism using rapid laboratory tests.
Molecular dynamics simulation of supercritical fluids
Branam, Richard D.
Axisymmetric injectors appear in a multitude of applications ranging from rocket engines to biotechnology. While experimentation is limited to larger injectors, much interest has been shown in the micro- and nano-scales as well. Experimentation at these scales can be cost prohibitive if even possible. Often, the operating regime involves supercritical fluids or complex geometries. Molecular dynamics modeling provides a unique way to explore these flow regimes, calculate hard to measure flow parameters accurately, and determine the value of potential improvements before investing in costly experiments or manufacturing. This research effort modeled sub- and supercritical fluid flow in a cylindrical tube being injected into a quiescent chamber. The ability of four wall models to provide an accurate simulation was compared. The simplest model, the diffuse wall, proved useful in getting results quickly but the results for the higher density cases are questionable, especially with respect to velocity profiles and density distributions. The one zone model, three layers of an fcc solid tethered to the lattice sites with a spring, proved very useful for this research primarily because it did not need as many CPU hours to equilibrate. The two zone wall uses springs as a two body potential and has a second stationary zone to hold the wall in place. The most complicated, the three zone wall, employed a reactionary zone, a stochastic zone and a stationary zone using a Lennard-Jones two body potential. Jet simulations were conducted on argon and nitrogen for liquid tube diameters from 20 to 65 A at both sub and supercritical temperatures (Ar: 130 K and 160 K, N2: 120 K and 130 K). The simulations focused on pressures above the critical pressure (Ar: 6 MPa, N2: 4 MPa). The diffusive wall showed some variation from the analytical velocity profile in the tube while the atomistically modeled walls performed very well. The walls were all able to maintain system temperature to reach
Dynamic characteristics of cylindrical shells considering Fluid-structure interaction
International Nuclear Information System (INIS)
Jhung, Myung Jo; Kim, Wal Tae; Ryu, Yong Ho
2009-01-01
To assure the reliability of cylinders or shells with fluid-filled annulus, it is necessary to investigate the modal characteristics considering fluid-structure interaction effect. In this study, theoretical background and several finite element models are developed for cylindrical shells with fluid-filled annulus considering fluid-structure interaction. The effect of the inclusion of the fluid-filled annulus on the natural frequencies is investigated, which frequencies are used for typical dynamic analyses such as responses spectrum, power spectral density and unit load excitation. Their response characteristics are addressed with respect to the various representations of the fluid-structure interaction effect
EDITORIAL: Changes to Fluid Dynamics Research in 2009 Changes to Fluid Dynamics Research in 2009
Funakoshi, Mitsuaki
2009-02-01
Welcome to the first issue of the modified Fluid Dynamics Research (FDR) journal, which is now being published by IOP Publishing on behalf of the Japan Society of Fluid Mechanics. Since its launch in 1986, FDR has become a well-established international journal that publishes theoretical, numerical and experimental studies contributing to the fundamental understanding and application of fluid phenomena. It has also been an invaluable resource for physicists and researchers in engineering interested in problems relevant to the motion of fluids. From 2009, FDR will be edited by a new international Editorial Board, with the strong intention of establishing the journal further and bringing it to a wider audience. In this new-look FDR, which will be published six times per year, readers will find several special sections containing high quality invited reviews and papers written by leading researchers who have been selected by the international Editorial Board. This is in addition to the regular papers on a variety of topical subjects by active researchers in the field. As before, there are no publication charges for standard articles, and now article numbering has been adopted, enabling accepted papers to be published online more quickly, ahead of print publication. In order to maintain a balanced and up-to-date perspective, we welcome feedback from our readers regarding the content of the journal, as well as suggestions for topics to cover and areas to highlight. Finally, I would like to thank our authors, members of the international Editorial Board, and the staff at IOP Publishing for producing this first issue. We hope you will enjoy reading this renewed and exciting journal for the international fluid dynamics community.
Second Order Dissipative Fluid Dynamics and Relativistic Heavy Ion Collisions
International Nuclear Information System (INIS)
Muronga, Azwinndini
2004-01-01
Non-ideal fluid dynamics is used to describe the space-time evolution of matter produced in relativistic nuclear collisions such as those at RHIC in BNL and at LHC in CERN. Dissipation is accounted for by employing causal theory of relativistic dissipative fluid dynamics derived from extended irreversible thermodynamics. The results are compared to those obtained by using Navier-Stokes theory and the ones obtained by perfect fluid approximation
Fluid dynamical form of the linear and nonlinear Schroedinger equations
International Nuclear Information System (INIS)
Spiegel, E.A.
1980-01-01
The Hamiltonian theory of perfect fluids admits the generalization to cases where the internal energy density depends on the gradient of mass density. Though the fluid dynamical equations are not greatly modified, when they are transformed into wave equations, special cases of the generalized fluid are seen to correspond to familiar Schroedinger equations. The irrotational nonrelativistic case is presented here and some of the advantages of the fluid point of view are mentioned. (orig.)
A newsletter on computational hydraulics and fluid dynamics
Energy Technology Data Exchange (ETDEWEB)
NONE
1997-12-31
This newsletter from Electricite de France (EdF) laboratory of hydraulics and fluid dynamics, reports on recent computer simulation studies of fluid flow in the domain of energy. Five papers were selected which deal with: unsteady flows in turbine blades of turbo-machineries, thermal exchanges between fluid and structures, multi-fluid thermal interactions in heat exchangers, heat transfers through windows, and flows induced by dam breaking. (J.S.)
Utilizing parallel optimization in computational fluid dynamics
Kokkolaras, Michael
1998-12-01
General problems of interest in computational fluid dynamics are investigated by means of optimization. Specifically, in the first part of the dissertation, a method of optimal incremental function approximation is developed for the adaptive solution of differential equations. Various concepts and ideas utilized by numerical techniques employed in computational mechanics and artificial neural networks (e.g. function approximation and error minimization, variational principles and weighted residuals, and adaptive grid optimization) are combined to formulate the proposed method. The basis functions and associated coefficients of a series expansion, representing the solution, are optimally selected by a parallel direct search technique at each step of the algorithm according to appropriate criteria; the solution is built sequentially. In this manner, the proposed method is adaptive in nature, although a grid is neither built nor adapted in the traditional sense using a-posteriori error estimates. Variational principles are utilized for the definition of the objective function to be extremized in the associated optimization problems, ensuring that the problem is well-posed. Complicated data structures and expensive remeshing algorithms and systems solvers are avoided. Computational efficiency is increased by using low-order basis functions and concurrent computing. Numerical results and convergence rates are reported for a range of steady-state problems, including linear and nonlinear differential equations associated with general boundary conditions, and illustrate the potential of the proposed method. Fluid dynamics applications are emphasized. Conclusions are drawn by discussing the method's limitations, advantages, and possible extensions. The second part of the dissertation is concerned with the optimization of the viscous-inviscid-interaction (VII) mechanism in an airfoil flow analysis code. The VII mechanism is based on the concept of a transpiration velocity
Dynamic wetting with viscous Newtonian and non-Newtonian fluids
International Nuclear Information System (INIS)
Wei, Y; Garoff, S; Rame, E; Walker, L M
2009-01-01
We examine various aspects of dynamic wetting with viscous Newtonian and non-Newtonian fluids. Rather than concentrating on the mechanisms that relieve the classic contact line stress singularity, we focus on the behavior in the wedge flow near the contact line which has the dominant influence on wetting with these fluids. Our experiments show that a Newtonian polymer melt composed of highly flexible molecules exhibits dynamic wetting behavior described very well by hydrodynamic models that capture the critical properties of the Newtonian wedge flow near the contact line. We find that shear thinning has a strong impact on dynamic wetting, by reducing the drag of the solid on the fluid near the contact line, while the elasticity of a Boger fluid has a weaker impact on dynamic wetting. Finally, we find that other polymeric fluids, nominally Newtonian in rheometric measurements, exhibit deviations from Newtonian dynamic wetting behavior.
Static and dynamic behaviours of helical spring in MR fluid
International Nuclear Information System (INIS)
Kaewunruen, S; Akintoye, O; Papaelias, M
2016-01-01
MR fluid has been used in automobile industry for vibration suppression device. However its dynamic interaction between structural spring and electro-magnetised MR fluid has not been thoroughly investigated. As a result, this paper highlights static and dynamic behaviours of helical spring interacting with MR fluid magnetised at various levels. Static hysteresis behaviours have been evaluated altogether with the dynamic modal properties of the system. Modal impact hammer testing technique was used to investigate the modal parameters. It is found that MR fluid improves the hysteresis capacity and dynamic properties of the systems when it is electro-magnetised. The outcome of this study will lead to a new development of new spring-dashpot system using MR fluid for better control in adaptive tuneable vibration damping and stiffness suppressing real-time dynamic motions such as the train body, passenger seats, train door, etc. (paper)
Fluid Dynamics Appearing during Simulated Microgravity Using Random Positioning Machines.
Wuest, Simon L; Stern, Philip; Casartelli, Ernesto; Egli, Marcel
2017-01-01
Random Positioning Machines (RPMs) are widely used as tools to simulate microgravity on ground. They consist of two gimbal mounted frames, which constantly rotate biological samples around two perpendicular axes and thus distribute the Earth's gravity vector in all directions over time. In recent years, the RPM is increasingly becoming appreciated as a laboratory instrument also in non-space-related research. For instance, it can be applied for the formation of scaffold-free spheroid cell clusters. The kinematic rotation of the RPM, however, does not only distribute the gravity vector in such a way that it averages to zero, but it also introduces local forces to the cell culture. These forces can be described by rigid body analysis. Although RPMs are commonly used in laboratories, the fluid motion in the cell culture flasks on the RPM and the possible effects of such on cells have not been examined until today; thus, such aspects have been widely neglected. In this study, we used a numerical approach to describe the fluid dynamic characteristic occurring inside a cell culture flask turning on an operating RPM. The simulations showed that the fluid motion within the cell culture flask never reached a steady state or neared a steady state condition. The fluid velocity depends on the rotational velocity of the RPM and is in the order of a few centimeters per second. The highest shear stresses are found along the flask walls; depending of the rotational velocity, they can reach up to a few 100 mPa. The shear stresses in the "bulk volume," however, are always smaller, and their magnitude is in the order of 10 mPa. In conclusion, RPMs are highly appreciated as reliable tools in microgravity research. They have even started to become useful instruments in new research fields of mechanobiology. Depending on the experiment, the fluid dynamic on the RPM cannot be neglected and needs to be taken into consideration. The results presented in this study elucidate the fluid
Meniscal Tear Film Fluid Dynamics Near Marx’s Line
Zubkov, V. S.
2013-07-03
Extensive studies have explored the dynamics of the ocular surface fluid, though theoretical investigations are typically limited to the use of the lubrication approximation, which is not guaranteed to be uniformly valid a-priori throughout the tear meniscus. However, resolving tear film behaviour within the meniscus and especially its apices is required to characterise the flow dynamics where the tear film is especially thin, and thus most susceptible to evaporatively induced hyperosmolarity and subsequent epithelial damage. Hence, we have explored the accuracy of the standard lubrication approximation for the tear film by explicit comparisons with the 2D Navier-Stokes model, considering both stationary and moving eyelids. Our results demonstrate that the lubrication model is qualitatively accurate except in the vicinity of the eyelids. In particular, and in contrast to lubrication theory, the solution of the full Navier-Stokes equations predict a distinct absence of fluid flow, and thus convective mixing in the region adjacent to the tear film contact line. These observations not only support emergent hypotheses concerning the formation of Marx\\'s line, a region of epithelial cell staining adjacent to the contact line on the eyelid, but also enhance our understanding of the pathophysiological consequences of the flow profile near the tear film contact line. © 2013 Society for Mathematical Biology.
AFDM: An advanced fluid-dynamics model
International Nuclear Information System (INIS)
Henneges, G.; Kleinheins, S.
1994-01-01
This volume of the Advanced Fluid-Dynamics Model (AFDM) documents the modeling of the equation of state (EOS) in the code. The authors present an overview of the basic concepts underlying the thermodynamics modeling and resulting EOS, which is a set of relations between the thermodynamic properties of materials. The AFDM code allows for multiphase-multimaterial systems, which they explore in three phase models: two-material solid, two-material liquid, and three-material vapor. They describe and compare two ways of specifying the EOS of materials: (1) as simplified analytic expressions, or (2) as tables that precisely describe the properties of materials and their interactions for mechanical equilibrium. Either of the two EOS models implemented in AFDM can be selected by specifying the option when preprocessing the source code for compilation. Last, the authors determine thermophysical properties such as surface tension, thermal conductivities, and viscosities in the model for the intracell exchanges of AFDM. Specific notations, routines, EOS data, plots, test results, and corrections to the code are available in the appendices
Computational Fluid Dynamics Modeling of Bacillus anthracis ...
Journal Article Three-dimensional computational fluid dynamics and Lagrangian particle deposition models were developed to compare the deposition of aerosolized Bacillus anthracis spores in the respiratory airways of a human with that of the rabbit, a species commonly used in the study of anthrax disease. The respiratory airway geometries for each species were derived from computed tomography (CT) or µCT images. Both models encompassed airways that extended from the external nose to the lung with a total of 272 outlets in the human model and 2878 outlets in the rabbit model. All simulations of spore deposition were conducted under transient, inhalation-exhalation breathing conditions using average species-specific minute volumes. Four different exposure scenarios were modeled in the rabbit based upon experimental inhalation studies. For comparison, human simulations were conducted at the highest exposure concentration used during the rabbit experimental exposures. Results demonstrated that regional spore deposition patterns were sensitive to airway geometry and ventilation profiles. Despite the complex airway geometries in the rabbit nose, higher spore deposition efficiency was predicted in the upper conducting airways of the human at the same air concentration of anthrax spores. This greater deposition of spores in the upper airways in the human resulted in lower penetration and deposition in the tracheobronchial airways and the deep lung than that predict
The Fluid Dynamics of Nascent Biofilms
Farthing, Nicola; Snow, Ben; Wilson, Laurence; Bees, Martin
2017-11-01
Many anti-biofilm approaches target mature biofilms with biochemical or physio-chemical interventions. We investigate the mechanics of interventions at an early stage that aim to inhibit biofilm maturation, focusing on hydrodynamics as cells transition from planktonic to surface-attached. Surface-attached cells generate flow fields that are relatively long-range compared with cells that are freely-swimming. We look at the effect of these flows on the biofilm formation. In particular, we use digital inline holographic microscopy to determine the three-dimensional flow due to a surface-attached cell and the effect this flow has on both tracers and other cells in the fluid. We compare experimental data with two models of cells on boundaries. The first approach utilizes slender body theory and captures many of the features of the experimental field. The second model develops a simple description in terms of singularity solutions of Stokes' flow, which produces qualitatively similar dynamics to both the experiments and more complex model but with significant computational savings. The range of validity of multiple cell arrangements is investigated. These two descriptions can be used to investigate the efficacy of actives developed by Unilever on nascent biofilms.
Fluid dynamic effects on staphylococci bacteria biofilms
Sherman, Erica; Bayles, Kenneth; Endres, Jennifer; Wei, Timothy
2016-11-01
Staphylococcus aureus bacteria are able to form biofilms and distinctive tower structures that facilitate their ability to tolerate treatment and to spread within the human body. The formation of towers, which break off, get carried downstream and serve to initiate biofilms in other parts of the body are of particular interest here. It is known that flow conditions play a role in the development, dispersion and propagation of biofilms in general. The influence of flow on tower formation, however, is not at all understood. This work is focused on the effect of applied shear on tower development. The hypothesis being examined is that tower structures form within a specific range of shear stresses and that there is an as yet ill defined fluid dynamic phenomenon that occurs hours before a tower forms. In this study, a range of shear stresses is examined that brackets 0.6 dynes/cm2, the nominal shear stress where towers seem most likely to form. This talk will include µPTV measurements and cell density data indicating variations in flow and biofilm evolution as a function of the applied shear. Causal relations between flow and biofilm development will be discussed.
Computational fluid dynamics in ventilation: Practical approach
Fontaine, J. R.
The potential of computation fluid dynamics (CFD) for conceiving ventilation systems is shown through the simulation of five practical cases. The following examples are considered: capture of pollutants on a surface treating tank equipped with a unilateral suction slot in the presence of a disturbing air draft opposed to suction; dispersion of solid aerosols inside fume cupboards; performances comparison of two general ventilation systems in a silkscreen printing workshop; ventilation of a large open painting area; and oil fog removal inside a mechanical engineering workshop. Whereas the two first problems are analyzed through two dimensional numerical simulations, the three other cases require three dimensional modeling. For the surface treating tank case, numerical results are compared to laboratory experiment data. All simulations are carried out using EOL, a CFD software specially devised to deal with air quality problems in industrial ventilated premises. It contains many analysis tools to interpret the results in terms familiar to the industrial hygienist. Much experimental work has been engaged to validate the predictions of EOL for ventilation flows.
Coslovich, Daniele; Kahl, Gerhard; Krakoviack, Vincent
2011-06-01
Over the past two decades, the dynamics of fluids under nanoscale confinement has attracted much attention. Motivation for this rapidly increasing interest is based on both practical and fundamental reasons. On the practical and rather applied side, problems in a wide range of scientific topics, such as polymer and colloidal sciences, rheology, geology, or biophysics, benefit from a profound understanding of the dynamical behaviour of confined fluids. Further, effects similar to those observed in confinement are expected in fluids whose constituents have strong size or mass asymmetry, and in biological systems where crowding and obstruction phenomena in the cytosol are responsible for clear separations of time scales for macromolecular transport in the cell. In fundamental research, on the other hand, the interest focuses on the complex interplay between confinement and structural relaxation, which is responsible for the emergence of new phenomena in the dynamics of the system: in confinement, geometric constraints associated with the pore shape are imposed to the adsorbed fluids and an additional characteristic length scale, i.e. the pore size, comes into play. For many years, the topic has been mostly experimentally driven. Indeed, a broad spectrum of systems has been investigated by sophisticated experimental techniques, while theoretical and simulation studies were rather scarce due to conceptual and computational issues. In the past few years, however, theory and simulations could largely catch up with experiments. On one side, new theories have been put forward that duly take into account the porosity, the connectivity, and the randomness of the confinement. On the other side, the ever increasing available computational power now allows investigations that were far out of reach a few years ago. Nowadays, instead of isolated state points, systematic investigations on the dynamics of confined fluids, covering a wide range of system parameters, can be realized
Nano- and microparticles at fluid and biological interfaces
Dasgupta, S.; Auth, T.; Gompper, G.
2017-09-01
Systems with interfaces are abundant in both technological applications and biology. While a fluid interface separates two fluids, membranes separate the inside of vesicles from the outside, the interior of biological cells from the environment, and compartmentalize cells into organelles. The physical properties of interfaces are characterized by interface tension, those of membranes are characterized by bending and stretching elasticity. Amphiphilic molecules like surfactants that are added to a system with two immiscible fluids decrease the interface tension and induce a bending rigidity. Lipid bilayer membranes of vesicles can be stretched or compressed by osmotic pressure; in biological cells, also the presence of a cytoskeleton can induce membrane tension. If the thickness of the interface or the membrane is small compared with its lateral extension, both can be described using two-dimensional mathematical surfaces embedded in three-dimensional space. We review recent work on the interaction of particles with interfaces and membranes. This can be micrometer-sized particles at interfaces that stabilise emulsions or form colloidosomes, as well as typically nanometer-sized particles at membranes, such as viruses, parasites, and engineered drug delivery systems. In both cases, we first discuss the interaction of single particles with interfaces and membranes, e.g. particles in external fields, non-spherical particles, and particles at curved interfaces, followed by interface-mediated interaction between two particles, many-particle interactions, interface and membrane curvature-induced phenomena, and applications.
Fluid Dynamic Experiments on Mush Column Magmatism
Flanagan-Brown, R. E.; Marsh, B. D.
2001-05-01
A vertically extensive stack of sills interconnected by pipe-like conduits extending from the mantle through the lithosphere and capped by a volcanic center is a magmatic mush column. At any instant at various locations it contains fractionated and primitive melts as pools of nearly crystal-free magma, pools of crystal-rich magma, thick beds of cumulates, open conduits, and conduits congested by cognate and wall debris. All boundaries of the system are sheathed by solidification fronts. With the wide range of local, characteristic length scales there is a commensurate range of solidification time scales. This creates a complicated series of resistances to magma flow and provides a variety of distinct local physical environments for the chemical modification of magma. The system is driven by over-pressure from the addition of new melt from below. The over-pressure propagates upward by moving magma which flushes conduits, disrupts cumulate beds, and pools or purges sills. A critical aspect of this process is the entrainment, transport, and deposition of crystals throughout the system. Picritic lavas charges with entrained (tramp) olivine of a wide compositional range erupted at many systems (e.g. Jan Mayen, Kilauea, Reunion, etc.) are the final expression of this process. That the size and abundance of these crystals is correlated with eruptive flux (Murata & Richter, AJS, 1966) suggests an important indicator of the overall dynamics of the mush column. A mush column of this basic nature is observed is observed in the McMurdo Dry Valleys region of Antarctica and is inferred beneath Hawaii and the ocean ridges. We have attempted to model this process by studying the entrainment, transport, and deposition of particles in a vertical stack of sills (Plexiglas tanks) connected by resistive conduits (check valves), over-pressured from the base, and open at the top. The system is about two meters in height with water and oil as fluids and particles with Reynolds numbers
Simulation of Tailrace Hydrodynamics Using Computational Fluid Dynamics Models; FINAL
International Nuclear Information System (INIS)
Cook, Chris B; Richmond, Marshall C
2001-01-01
This report investigates the feasibility of using computational fluid dynamics (CFD) tools to investigate hydrodynamic flow fields surrounding the tailrace zone below large hydraulic structures. Previous and ongoing studies using CFD tools to simulate gradually varied flow with multiple constituents and forebay/intake hydrodynamics have shown that CFD tools can provide valuable information for hydraulic and biological evaluation of fish passage near hydraulic structures. These studies however are incapable of simulating the rapidly varying flow fields that involving breakup of the free-surface, such as those through and below high flow outfalls and spillways. Although the use of CFD tools for these types of flow are still an active area of research, initial applications discussed in this report show that these tools are capable of simulating the primary features of these highly transient flow fields
Simulation of Tailrace Hydrodynamics Using Computational Fluid Dynamics Models
Energy Technology Data Exchange (ETDEWEB)
Cook, Christopher B.; Richmond, Marshall C.
2001-05-01
This report investigates the feasibility of using computational fluid dynamics (CFD) tools to investigate hydrodynamic flow fields surrounding the tailrace zone below large hydraulic structures. Previous and ongoing studies using CFD tools to simulate gradually varied flow with multiple constituents and forebay/intake hydrodynamics have shown that CFD tools can provide valuable information for hydraulic and biological evaluation of fish passage near hydraulic structures. These studies however are incapable of simulating the rapidly varying flow fields that involving breakup of the free-surface, such as those through and below high flow outfalls and spillways. Although the use of CFD tools for these types of flow are still an active area of research, initial applications discussed in this report show that these tools are capable of simulating the primary features of these highly transient flow fields.
Optics and Fluid Dynamics Department annual progress report for 2002
DEFF Research Database (Denmark)
Bindslev, H.; Hanson, Steen Grüner; Lynov, Jens-Peter
2003-01-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1) laser systems and optical materials (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The departmenthas core competences in: optical sensors......, optical materials, optical storage, biophotonics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, includingEURATOM, by Danish research councils and by industry. A summary of the activities in 2002...
Optics and Fluid Dynamics Department annual progress report for 2000
DEFF Research Database (Denmark)
Hanson, Steen Grüner; Johansen, Per Michael; Lynov, Jens-Peter
2001-01-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1) optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The department has corecompetences in: optical sensors, optical materials......, optical storage, biooptics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by Danishresearch councils and by industry. A summary of the activities in 2000 is presented....
Optics and Fluid Dynamics Department annual progress report for 2003
DEFF Research Database (Denmark)
Bindslev, H.; Hanson, Steen Grüner; Lynov, Jens-Peter
2004-01-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1) laser systems and optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The departmenthas core competences in: optical sensors......, optical materials, optical storage, biophotonics, numerical modelling and information processing, non-linear dynamics, fusion plasma physics and plasma technology. The research is supported by several EUprogrammes, including EURATOM, by Danish research councils and by industry. A summary of the activities...
Optics and Fluid Dynamics Department annual progress report for 1999
DEFF Research Database (Denmark)
Hanson, Steen Grüner; Johansen, Per Michael; Lynov, Jens-Peter
2000-01-01
The Optics and Fluid Dynamics Department performs basic and applied research within the three programmes: (1) optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The department has core competences in:optical sensors, optical materials, biooptics......, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by research councils and by industry. Asummary of the activities in 1999 is presented....
Optimal control of molecular motion expressed through quantum fluid dynamics
Dey, Bijoy K.; Rabitz, Herschel; Askar, Attila
2000-04-01
A quantum fluid-dynamic (QFD) control formulation is presented for optimally manipulating atomic and molecular systems. In QFD the control quantum system is expressed in terms of the probability density ρ and the quantum current j. This choice of variables is motivated by the generally expected slowly varying spatial-temporal dependence of the fluid-dynamical variables. The QFD approach is illustrated for manipulation of the ground electronic state dynamics of HCl induced by an external electric field.
Dynamic model of the electrorheological fluid based on measurement results
International Nuclear Information System (INIS)
Krivenkov, K; Ulrich, S; Bruns, R
2013-01-01
To develop modern applications for vibration decoupling based on electrorheological fluids with suitable control strategies, an appropriate mathematical model of the ERF is necessary. The devices mostly used have annular-shape electrorheological valves. This requires the use of flow channels to measure the static and dynamic properties of the electrorheological fluids in similar flow conditions. Particularly for the identification of the dynamic behavior of the fluids, the influences of the non-electrorheological properties on the overall system must be taken into account. In this contribution three types of parameters with several nonlinear dependencies for the mapping of the static and dynamic properties of the ERF are considered: electro-rheological, hydraulic and electrical. The mathematical model introduced can precisely demonstrate the static and dynamic behavior of the electrorheological fluid and can be used for the future design of real systems for vibration decoupling or other systems with high dynamic requirements.
Analytical Problems in Exposing Amperometric Enzyme Biosensors to Biological Fluids
Directory of Open Access Journals (Sweden)
Gaia Rocchitta
2016-05-01
Full Text Available Enzyme-based chemical biosensors are based on biological recognition. In order to operate, the enzymes must be available to catalyze a specific biochemical reaction and be stable under the normal operating conditions of the biosensor. Design of biosensors is based on knowledge about the target analyte, as well as the complexity of the matrix in which the analyte has to be quantified. This article reviews the problems resulting from the interaction of enzyme-based amperometric biosensors with complex biological matrices containing the target analyte(s. One of the most challenging disadvantages of amperometric enzyme-based biosensor detection is signal reduction from fouling agents and interference from chemicals present in the sample matrix. This article, therefore, investigates the principles of functioning of enzymatic biosensors, their analytical performance over time and the strategies used to optimize their performance. Moreover, the composition of biological fluids as a function of their interaction with biosensing will be presented.
Methods to Enrich Exosomes from Conditioned Media and Biological Fluids.
Sharma, Shayna; Scholz-Romero, Katherin; Rice, Gregory E; Salomon, Carlos
2018-01-01
Exosomes are nano-vesicles which can transport a range of molecules including but not limited to proteins and miRNA. This ability of exosomes renders them useful in cellular communication often resulting in biological changes. They have several functions in facilitating normal biological processes such as immune responses and an involvement in pregnancy. However, they have also been linked to pathological conditions including cancer and pregnancy complications such as preeclampsia. An understanding for the role of exosomes in preeclampsia is based on the ability to purify and characterize exosomes. There have been several techniques proposed for the enrichment of exosomes such as ultracentrifugation, density gradient separation, and ultrafiltration although there is no widely accepted optimized technique. Here we describe a workflow for isolating exosomes from cell-conditioned media and biological fluids using a combination of centrifugation, buoyant density, and ultrafiltration approaches.
The complex fluid dynamics of simple diffusion
Vold, Erik
2017-11-01
Diffusion as the mass transport process responsible for mixing fluids at the atomic level is often underestimated in its complexity. An initial discontinuity between two species of different atomic masses exhibits a mass density discontinuity under isothermal pressure equilibrium implying equal species molar densities. The self-consistent kinetic transport processes across such an interface leads to a zero sum of mass flux relative to the center of mass and so diffusion alone cannot relax an initially stationary mass discontinuity nor broaden the density profile at the interface. The diffusive mixing leads to a molar imbalance which drives a center of mass velocity which moves the heavier species toward the lighter species leading to the interfacial density relaxation. Simultaneously, the species non-zero molar flux modifies the pressure profile in a transient wave and in a local perturbation. The resulting center of mass velocity has two components; one, associated with the divergence of the flow, persists in the diffusive mixing region throughout the diffusive mixing process, and two, travelling waves at the front of the pressure perturbations propagate away from the mixing region. The momentum in these waves is necessary to maintain momentum conservation in the center of mass frame. Thus, in a number of ways, the diffusive mixing provides feedback into the small scale advective motions. Numerical methods which diffuse all species assuming P-T equilibrium may not recover the subtle dynamics of mass transport at an interface. Work performed by the LANS, LLC, under USDOE Contract No. DE-AC52-06NA25396, funded by the (ASC) Program.
International Nuclear Information System (INIS)
Cui, S.T.; Cummings, P.T.; Cochran, H.D.
1999-01-01
We study the effect of wall endash fluid interactions on the state conditions and the effective properties of a model dodecane fluid confined between parallel solid walls. A significant increase in the effective density of the confined fluid is observed with increasing strength of the wall endash fluid interaction. The effect of the wall endash fluid interaction on the rotational relaxation and diffusional relaxation of the fluid is seen in the significant slowing down of the relaxation with increasing wall endash fluid interaction strength. The difference between the confined fluid and the three-dimensional bulk fluid is demonstrated by the strong anisotropy of the dynamical properties, the molecular rotation, and self-diffusion. The viscosity of the confined fluid shows a large difference between weak and strong wall endash fluid interactions, and a significant difference from bulk fluid at low shear rate. copyright 1999 American Institute of Physics
Dynamic Characteristics of Magneto-Fluid Supports
Directory of Open Access Journals (Sweden)
V. A. Chernobai
2008-01-01
Full Text Available The paper considers a vibro-protective magneto-fluid support that uses elastic properties of magnetic fluid with a free surface in magnetic field.The paper has experimentally revealed that the analyzed structure is characterized by better noise absorbing characteristics.The conducted experiments have made it possible to conclude that there is a possibility to use vibro-protective magneto-fluid supports within the frequency range from 0 to 300 Hz, amplitudes up to 2 mm and unit load up to 2,5 · 10 4 Н/м².
Fluid dynamics of parallel plates Viscometer: A case study of ...
African Journals Online (AJOL)
The fluid dynamics of parallel plates viscometer is investigated mathematically using both the Navier-Stokes and continuity equations for an incompressible viscous fluid. The problem admits similarity solutions, thereby reducing the unsteady Navier-Stokes equations to a parameter dependent fourth order nonlinear ordinary ...
Parcel Eulerian-Lagrangian fluid dynamics for rotating geophysical flows
Bokhove, Onno; Oliver, M.
2006-01-01
Parcel Eulerian-Lagrangian Hamiltonian formulations have recently been used in structure-preserving numerical schemes, asymptotic calculations and in alternative explanations of fluid parcel (in) stabilities. A parcel formulation describes the dynamics of one fluid parcel with a Lagrangian kinetic
Computational fluid dynamics applied to gas-liquid contactors.
Delnoij, E.; Kuipers, J.A.M.; van Swaaij, Willibrordus Petrus Maria
1997-01-01
In this paper a `hierarchy of models¿ is discussed to study the fluid dynamic behaviour of gas-liquid bubble columns. This `hierarchy of models¿ consists of a Eulerian-Eulerian two fluid model, a Eulerian-Lagrangian discrete bubble model and a Volume Tracking or Marker Particle model. These models
Validation of Computational Fluid Dynamics Simulations for Realistic Flows (Preprint)
National Research Council Canada - National Science Library
Davoudzadeh, Farhad
2007-01-01
Strategies used to verify and validate computational fluid dynamics (CFD) calculations are described via case studies of realistic flow simulations, each representing a complex flow physics and complex geometry...
ADDRESSING ENVIRONMENTAL ENGINEERING CHALLENGES WITH COMPUTATIONAL FLUID DYNAMICS
This paper discusses the status and application of Computational Fluid Dynamics )CFD) models to address environmental engineering challenges for more detailed understanding of air pollutant source emissions, atmospheric dispersion and resulting human exposure. CFD simulations ...
The stability and dynamic behaviour of fluid-loaded structures
CSIR Research Space (South Africa)
Suliman, Ridhwaan
2015-07-01
Full Text Available ECCOMAS Young Investigators Conference 6th GACM Colloquium, July 20–23, 2015, Aachen, Germany The stability and dynamic behaviour of fluid-loaded structures R. Suliman, N. Peake Abstract. The deformation of slender elastic structures due...
Verification and validation in computational fluid dynamics
Oberkampf, William L.; Trucano, Timothy G.
2002-04-01
Verification and validation (V&V) are the primary means to assess accuracy and reliability in computational simulations. This paper presents an extensive review of the literature in V&V in computational fluid dynamics (CFD), discusses methods and procedures for assessing V&V, and develops a number of extensions to existing ideas. The review of the development of V&V terminology and methodology points out the contributions from members of the operations research, statistics, and CFD communities. Fundamental issues in V&V are addressed, such as code verification versus solution verification, model validation versus solution validation, the distinction between error and uncertainty, conceptual sources of error and uncertainty, and the relationship between validation and prediction. The fundamental strategy of verification is the identification and quantification of errors in the computational model and its solution. In verification activities, the accuracy of a computational solution is primarily measured relative to two types of highly accurate solutions: analytical solutions and highly accurate numerical solutions. Methods for determining the accuracy of numerical solutions are presented and the importance of software testing during verification activities is emphasized. The fundamental strategy of validation is to assess how accurately the computational results compare with the experimental data, with quantified error and uncertainty estimates for both. This strategy employs a hierarchical methodology that segregates and simplifies the physical and coupling phenomena involved in the complex engineering system of interest. A hypersonic cruise missile is used as an example of how this hierarchical structure is formulated. The discussion of validation assessment also encompasses a number of other important topics. A set of guidelines is proposed for designing and conducting validation experiments, supported by an explanation of how validation experiments are different
Effect of Fluid Dynamic Viscosity on the Strength of Chalk
DEFF Research Database (Denmark)
Hedegaard, K.; Fabricius, Ida Lykke
The mechanical strength of high porosity and weakly cemented chalk is affected by the fluid in the pores. In this study, the effect of the dynamic viscosity of non-polar fluids has been measured on outcrop chalk from Sigerslev Quarry, Stevns, Denmark. The outcome is that the measured strength...... of the chalk decreases with increasing dynamic viscosity. The proposed qualitative explanation is that pressure difference supports and enhances the generation of microscopic shear and tensile failures....
Meteorological fluid dynamics asymptotic modelling, stability and chaotic atmospheric motion
Zeytounian, Radyadour K
1991-01-01
The author considers meteorology as a part of fluid dynamics. He tries to derive the properties of atmospheric flows from a rational analysis of the Navier-Stokes equations, at the same time analyzing various types of initial and boundary problems. This approach to simulate nature by models from fluid dynamics will be of interest to both scientists and students of physics and theoretical meteorology.
Development of a theoretical framework for analyzing cerebrospinal fluid dynamics
DEFF Research Database (Denmark)
Cohen, Benjamin; Voorhees, Abram; Vedel, Søren
2009-01-01
Background: To date hydrocephalus researchers acknowledge the need for rigorous but utilitarian fluid mechanics understanding and methodologies in studying normal and hydrocephalic intracranial dynamics. Pressure volume models and electric circuit analogs introduced pressure into volume conservat......Background: To date hydrocephalus researchers acknowledge the need for rigorous but utilitarian fluid mechanics understanding and methodologies in studying normal and hydrocephalic intracranial dynamics. Pressure volume models and electric circuit analogs introduced pressure into volume...
Fluid Dynamics of Jets with Applications to V/STOL.
1982-01-01
WITH APPLICATIONS TO V/ STOL Papers presented and discussions held at the Fluid Dynamics Panel Symposium held at the Fundaqao Calouste Gulbenkian, Lisbon...Ltd Iarford House, 7-9 Charlotte St. London. WIP lHD IIJ FOREWORD -.The Symposium on Fluid Dynamics of Jets with Applications to V/ STOL was planned in...Senior Scientific Advisor Pavilhao de Maquinas ONERA Istituto Superior Tecnico 29 Avenue de ]a Division Leclerc 1096 Lisboa Codex, Portugal 92320
A computational fluid dynamics algorithm on a massively parallel computer
International Nuclear Information System (INIS)
Jespersen, D.C.; Levit, C.
1989-01-01
The discipline of computational fluid dynamics is demanding ever-increasing computational power to deal with complex fluid flow problems. The authors investigate the performance of a finite-difference computational fluid dynamics algorithm on a massively parallel computer, the Connection Machine. Of special interest is an implicitly time-stepping algorithm; to obtain maximum performance from the Connection Machine, it is necessary to use a nonstandard algorithm to solve the linear systems that arise in the implicit algorithm. The authors find that the Connection Machine can achieve very high computation rates on both explicit and implicit algorithms. The performance of the Connection Machine puts it in the same class as conventional supercomputers
Exploration of Fluid Dynamics in Perioperative Patients Using Bioimpedance Analysis.
Chong, Jae Uk; Nam, Sangguen; Kim, Hee Jung; Lee, Rami; Choi, Yunjung; Lee, Jae Gil; Kim, Kyung Sik
2016-05-01
Perioperative fluid restriction is advocated to reduce complications after major surgeries. Current methods of monitoring body fluids rely on indirect volume markers that may at times be inadequate. In our study, bioimpedance analysis (BIA) was used to explore fluid dynamics, in terms of intercompartmental shift, of perioperative patients undergoing operation for hepato-pancreato-biliary (HPB) diseases. A retrospective review was conducted, examining 36 patients surgically treated for HPB diseases between March 2010 and August 2012. Body fluid compartments were estimated via BIA at baseline (1 day prior to surgery), immediately after surgery, and on postoperative day 1, recording fluid balance during and after procedures. Patients were stratified by net fluid status as balanced (≤500 mL) or imbalanced (>550 mL) and outcomes of BIA compared. Mean net fluid balance volumes in balanced (n = 16) and imbalanced (n = 20) patient subsets were 231.41 ± 155.44 and 1050.18 ± 548.77 mL, respectively. Total body water (TBW) (p = 0.091), extracellular water (ECW) (p = 0.125), ECW/TBW (p = 0.740), and intracellular water (ICW) (p = 0.173) did not fluctuate significantly in fluid-balanced patients. Although TBW (p = 0.069) in fluid-imbalanced patients did not change significantly (relative to baseline), ECW (p = 0.001), ECW/TBW (p = 0.019), and ICW (p = 0.012) showed significant postoperative increases. The exploration of fluid dynamics using BIA has shown importance of balanced fluid management during perioperative period. Increased ECW/TBW in fluid-imbalanced patients suggests possible causality for the development of ascites or fluid collections during postoperative period in patients undergoing HPB operations.
Experimental analysis on MR fluid channel flow dynamics with complex fluid-wall interactions
International Nuclear Information System (INIS)
Nishiyama, Hideya; Takana, Hidemasa; Shinohara, Keisuke; Mizuki, Kotoe; Katagiri, Kazunari; Ohta, Makoto
2011-01-01
MR fluid plugging performance by aggregation of magnetized particles in MR fluid is recently expected to be one of the most promising applications in medical or safety devices, such as blood flow control, steam issuing shut-down valve and fuel supply control for automobile. In this study, dynamic response of MR fluid plugging and its breakdown in a pressure mode with complex fluid-wall interactions was experimentally investigated, considering the effects of magnetic flux density, wall surface structure, wall permeability and wall elasticity of tube. Higher endurance pressure is obtained for wall surface groove structure and for steel wall due to a strong anchoring effect by rigid cluster formation in a concave region and strong MR fluid column formation in a channel core region, respectively. Furthermore, MR fluid plugging performance and the fluid storage characteristic of PVA tube as a bio-material was clarified. Because of the large radial expansion of the tube at the applied magnetic region in a pressure mode, PVA tube shows unique characteristics, such as storing MR fluid under magnetic field and MR fluid jet issuing under releasing magnetic field. - Research Highlights: → The dynamic response of MR fluid plugging and its breakdown in pressure mode with complex fluid/wall interactions is experimentally investigated. → The inlet pressures at the breakdown of MR fluid plug are evaluated for acrylic and steel grooved walls in pressure flow mode under magnetic field. → MR fluid plugging performance and the storage characteristic of a PVA tube as a bio-material are shown.
Review of Prospects of Biological Fluid Biomarkers in Osteoarthritis.
Nguyen, Lich Thi; Sharma, Ashish Ranjan; Chakraborty, Chiranjib; Saibaba, Balaji; Ahn, Moo-Eob; Lee, Sang-Soo
2017-03-12
Osteoarthritis (OA) is a degenerative disease of the joints and is one of the leading causes of disability in adults. However, there are no key therapeutics for OA and medical treatment is based on managing the symptoms and slowing down progression of the disease. Diagnostics based on clinical examination and radiography have provided little information about metabolic changes in joint tissues, disease onset and progression. Due to lack of effective methods for early detection and evaluation of treatment outcome, the measurement of biochemical markers (biomarkers) shows promise as a prospective method aiding in disease monitoring. OA biomarkers that are present in biological fluids such as blood, urine and synovial fluid, sources that are easily isolated from body, are of particular interest. Moreover, there are increasingly more studies identifying and developing new biomarkers for OA. In this review, efforts have been made to summarize the biomarkers that have been reported in recent studies on patients. We also tried to classify biomarkers according to tissue metabolism (bone, cartilage and synovial metabolism markers), pathological pathways (inflammatory and genetic markers) and biological function (chemokines, growth factors, acute phase proteins, etc.).
Dynamic light scattering with applications to chemistry, biology, and physics
Berne, Bruce J
2000-01-01
Lasers play an increasingly important role in a variety of detection techniques, making inelastic light scattering a tool of growing value in the investigation of dynamic and structural problems in chemistry, biology, and physics. Until the initial publication of this work, however, no monograph treated the principles behind current developments in the field.This volume presents a comprehensive introduction to the principles underlying laser light scattering, focusing on the time dependence of fluctuations in fluid systems; it also serves as an introduction to the theory of time correlation f
Interface dynamics and domain growth in thermally bistable fluids
International Nuclear Information System (INIS)
Shaviv, N.J.; Regev, O.
1994-01-01
Domain growth kinetics in a thermally bistable fluid with heat diffusion is studied. The time evolution of interfaces between the stable phases is calculated numerically in two dimensions and compared to some general results derived analytically. The qualitative behavior is found to be similar to the previously studied cases where fluid dynamics was neglected. There are, however, several important differences such as the value of the dynamical exponent, which determines the power law of the system's correlation length growth. The introduction of fluid motion into the model introduces additional properties, unfamiliar to previously studied systems, like the change of the pressure or the size of the system. This behavior is due to the advection of mass. The present model may have general relevance to any system modeled by a real Ginzburg-Landau-type equation coupled to fluid dynamical conservation equations. In particular, it is a step forward on the way to a faithful modeling of thermally bistable cloudy astrophysical media
Hard sphere dynamics for normal and granular fluids.
Dufty, James W; Baskaran, Aparna
2005-06-01
A fluid of N smooth, hard spheres is considered as a model for normal (elastic collision) and granular (inelastic collision) fluids. The potential energy is discontinuous for hard spheres so that the pairwise forces are singular and the usual forms of Newtonian and Hamiltonian mechanics do not apply. Nevertheless, particle trajectories in the N particle phase space are well defined and the generators for these trajectories can be identified. The first part of this presentation is a review of the generators for the dynamics of observables and probability densities. The new results presented in the second part refer to applications of these generators to the Liouville dynamics for granular fluids. A set of eigenvalues and eigenfunctions of the generator for this Liouville dynamics system is identified in a special stationary representation. This provides a class of exact solutions to the Liouville equation that are closely related to hydrodynamics for granular fluids.
Energetics and dynamics of excess electrons in simple fluids
International Nuclear Information System (INIS)
Space, B.
1992-01-01
Excess electronic dynamical and equilibrium properties are modeled in both polarizable and nonpolarizable noble gas fluids. Explicit dynamical calculations are carried out for excess electrons in fluid helium, where excess electronic eigenstates are localized. Energetics and dynamics are considered for fluids which span the entire range of polarizability present in the rare gases. Excess electronic eigenstates and eigenvalues are calculated for fluids of helium, argon and xenon. Both equilibrium and dynamical information is obtained from the calculation of these wavefunctions. A surface hopping trajectory method for studying nonadiabatic excess electronic relaxation in condensed systems is used to explore the nonadiabatic relaxation after photoexciting an equilibrated excess electron in dense fluid helium. The different types on nonadiabatic phenomena which are important in excess electronic relaxation are surveyed. The same surface hopping trajectory method is also used to study the rapid nonadiabatic relaxation after an excess electron is injected into unperturbed fluid helium. Several distinctively different relaxation processes, characterized by their relative importance at different times during the relaxation to a localized equilibrium state, are detailed. Though the dynamical properties of excess electrons under the conditions considered here have never been studied before, the behavior is remarkably similar to that observed in both experimental and theoretical studies of electron hydration dynamics, indicating that the processes described may be very general relaxation mechanisms for localization and trapping in fluids. Additionally, ground state energies of an excess electron, e 0 , are computed as a function of solvent density using model electron-atom pseudopotentials in fluid helium, argon, and xenon. The nonuniqueness of the pseudopotential description of electron-molecule interactions is demonstrated
Long term behavior of dynamic equilibria in fluid queuing networks
R. Cominetti (Roberto); J. Correa (José); N.K. Olver (Neil)
2017-01-01
textabstractA fluid queuing network constitutes one of the simplest models in which to study flow dynamics over a network. In this model we have a single source-sink pair and each link has a per-time-unit capacity and a transit time. A dynamic equilibrium (or equilibrium flow over time) is a flow
Optics and Fluid Dynamics Department. Annual Progress Report for 2002
International Nuclear Information System (INIS)
Bindslev, H.; Hanson, S.G.; Lynov, J.P.; Petersen, P.M.; Skaarup, B.
2003-05-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1 Laser systems and optical materials (2 Optical diagnostics and information processing and (3 Plasma and fluid dynamics. The department has core competences in: optical sensors, optical materials, optical storage, biophotonics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by Danish research councils and by industry. A summary of the activities in 2002 is presented. (au)
TDHF and fluid dynamics of nuclear collective motions
International Nuclear Information System (INIS)
Di Nardo, M.; Di Toro, M.; Giansiracusa, G.; Lombardo, U.; Russo, G.
1983-01-01
The nuclear fluid dynamical equations are derived from a mean field description of the nuclear dynamics. Simple approximate solutions, corresponding to generalized scaling modes, are worked out for rotations and vibrations, with the evaluation of inertial parameters and flow patterns. Giant resonances are shown to be quite well described within an irrotational ansatz, which is equivalent to a lowest multipoles (up to lsub(max)=2) distortion of the momentum distribution. The physical meaning of a higher order truncation of the TDHF-Fluid-Dynamics chain is finally discussed with its implication on low lying states and on some description of the Landau damping. (author)
Optics and Fluid Dynamics Department. Annual progress report for 2001
International Nuclear Information System (INIS)
Bindslev, H.; Hanson, S.G.; Lynov, J.P.; Petersen, P.M.; Skaarup, B.
2002-03-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: 1) laser systems and optical materials, 2) optical diagnostics and information processing and 3) plasma and fluid dynamics. The department has core competence in: optical sensors, optical materials, optical storage, bio-optics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by Danish research councils and by industry. A summary of the activities in 2001 is presented. (au)
Optics and Fluid Dynamics Department annual progress report for 2001
DEFF Research Database (Denmark)
Bindslev, H.; Hanson, Steen Grüner; Lynov, Jens-Peter
2002-01-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1) laser systems and optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The departmenthas core competences in: optical sensors......, optical materials, optical storage, biooptics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM,by Danish research councils and by industry. A summary of the activities in 2001 is presented....
Optics and Fluid Dynamics Department annual progress report for 2000
International Nuclear Information System (INIS)
Hanson, S.G.; Johansen, P.M.; Lynov, J.P.; Skaarup, B.
2001-05-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1) optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The department has core competence in: optical sensors, optical materials, optical storage, bio-optics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by Danish research councils and by industry. A summary of the activities in 2000 is presented. (au)
Optics and Fluid Dynamics Department. Annual progress report for 2003
Energy Technology Data Exchange (ETDEWEB)
Bindslev, H.; Hanson, S.G.; Lynov, J.P.; Petersen, P.M.; Skaarup, B. (eds.)
2004-05-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1 laser systems and optical materials, (2 optical diagnostics and information processing and (3 plasma and fluid dynamics. The department has core competences in: optical sensors, optical materials, optical storage, biophotonics, numerical modelling and information processing, non-linear dynamics, fusion plasma physics and plasma technology. The research is supported by several EU programmes, including EURATOM, by Danish research councils and by industry. A summary of the activities in 2003 is presented. (au)
Optics and Fluid Dynamics Department. Annual Progress Report for 2002
Energy Technology Data Exchange (ETDEWEB)
Bindslev, H.; Hanson, S.G.; Lynov, J.P.; Petersen, P.M.; Skaarup, B
2003-05-01
The Optics and Fluid Dynamics Department performs basic and applied research within three scientific programmes: (1) Laser systems and optical materials (2) Optical diagnostics and information processing and (3) Plasma and fluid dynamics. The department has core competences in: optical sensors, optical materials, optical storage, biophotonics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by Danish research councils and by industry. A summary of the activities in 2002 is presented. (au)
Prandtl, Ludwig
1953-01-01
Equilibrium of liquids and gases ; kinematics : dynamics of frictionless fluids ; motion of viscous fluids : turbulence : fluid resistance : practical applications ; flow with appreciable volume changes (dynamics of gases) ; miscellaneous topics.
Fluid dynamics of moving fish in a two-dimensional multiparticle collision dynamics model
Reid, Daniel A. P.; Hildenbrandt, H.; Hemelrijk, C. K.; Padding, J.T.
2012-01-01
The fluid dynamics of animal locomotion, such as that of an undulating fish, are of great interest to both biologists and engineers. However, experimentally studying these fluid dynamics is difficult and time consuming. Model studies can be of great help because of their simpler and more detailed
Effect of centrifugation on dynamic susceptibility of magnetic fluids
International Nuclear Information System (INIS)
Pshenichnikov, Alexander; Lebedev, Alexander; Lakhtina, Ekaterina; Kuznetsov, Andrey
2017-01-01
Highlights: • Six samples of magnetic fluid were obtained by centrifuging two base ferrocolloids. • Aggregates in magnetic fluids are main reason of dynamic susceptibility dispersion. • Centrifugation is an effective way of changing the dynamic susceptibility. - Abstract: The dispersive composition, dynamic susceptibility and spectrum of times of magnetization relaxation for six samples of magnetic fluid obtained by centrifuging two base colloidal solutions of the magnetite in kerosene was investigated experimentally. The base solutions differed by the concentration of the magnetic phase and the width of the particle size distribution. The procedure of cluster analysis allowing one to estimate the characteristic sizes of aggregates with uncompensated magnetic moments was described. The results of the magnetogranulometric and cluster analyses were discussed. It was shown that centrifugation has a strong effect on the physical properties of the separated fractions, which is related to the spatial redistribution of particles and multi-particle aggregates. The presence of aggregates in magnetic fluids is interpreted as the main reason of low-frequency (0.1–10 kHz) dispersion of the dynamic susceptibility. The obtained results count in favor of using centrifugation as an effective means of changing the dynamic susceptibility over wide limits and obtaining fluids with the specified type of susceptibility dispersion.
Fluid dynamic constraints on resource acquisition in small pelagic organisms
DEFF Research Database (Denmark)
Kiørboe, Thomas
2016-01-01
Physicists have long examined the fluid dynamics of swimming at low Reynolds number, but the main scope has rarely been to understand the behavior and ecology of microorganisms. However, many ecological questions about the functioning of small aquatic organisms can only be addressed by the applic......Physicists have long examined the fluid dynamics of swimming at low Reynolds number, but the main scope has rarely been to understand the behavior and ecology of microorganisms. However, many ecological questions about the functioning of small aquatic organisms can only be addressed...... by the application of formal fluid physics. Here, I examine resource acquisition mechanisms in small aquatic organisms, ranging from uptake of dissolved molecules to feeding on suspended particulate prey, and examine how organism behaviors and morphologies may be shaped by the often non-intuitive small-scale fluid...
Jet-medium interaction and conformal relativistic fluid dynamics
Yan, Li; Jeon, Sangyong; Gale, Charles
2018-03-01
A formalism to study the mode-by-mode response to the energy deposition of external hard partons propagating in a relativistic fluid is developed, based on a semianalytical solution of conformal fluid dynamics. The soft-particle production resulting from the jet-medium interaction is calculated, and the recoil of the viscous medium is studied for different orientations of the relativistic jets and for different values of the specific shear viscosity η /s .
Computational fluid dynamics open a new world for designers
International Nuclear Information System (INIS)
Mitsuda, Masahiko; Hosokawa, Yoshiyuki; Oda, Tsuyoshi; Kobayashi, Toshiyuki; Akamatsu, Hiroshi; Yamada, Hitoshi
2001-01-01
As a result of recent improvements in computer performance, practical applications of computational fluid dynamics (CFD) are becoming increasingly common. No longer is the macroscopic flow field merely visualized. It has now become possible to closely investigate boundary issues such as the flow force, the heat transfer, the solid-gas-liquid interface motion. Detailed fluid phenomena is now available to designers and this promises great future developments for various processes. This paper discusses these exciting new developments. (author)
Resolving Neighbourhood Relations in a Parallel Fluid Dynamic Solver
Frisch, Jerome
2012-06-01
Computational Fluid Dynamics simulations require an enormous computational effort if a physically reasonable accuracy should be reached. Therefore, a parallel implementation is inevitable. This paper describes the basics of our implemented fluid solver with a special aspect on the hierarchical data structure, unique cell and grid identification, and the neighbourhood relations in-between grids on different processes. A special server concept keeps track of every grid over all processes while minimising data transfer between the nodes. © 2012 IEEE.
Improved Pyrolysis Micro reactor Design via Computational Fluid Dynamics Simulations
2017-05-23
NUMBER (Include area code) 23 May 2017 Briefing Charts 25 April 2017 - 23 May 2017 Improved Pyrolysis Micro-reactor Design via Computational Fluid... PYROLYSIS MICRO-REACTOR DESIGN VIA COMPUTATIONAL FLUID DYNAMICS SIMULATIONS Ghanshyam L. Vaghjiani* DISTRIBUTION A: Approved for public release...Approved for public release, distribution unlimited. PA Clearance 17247 Chen-Source (>240 references from SciFinder as of 5/1/17): Flash pyrolysis
Dynamic stability of a spinning tube conveying a flowing fluid
International Nuclear Information System (INIS)
Benedetti, G.A.
1985-02-01
When a fluid flows inside a tube, the deformations of the tube can interact with the fluid flowing within it and these dynamic interactions can result in significant lateral motions of the tube and the flowing fluid. The purpose of this report is to examine the dynamic stability of a spinning tube through which an incompressible fluid is flowing. The tube can be considered as either a hollow beam or as a hollow cable. The analytical results can be applied to spinning or stationary tubes through which fluids are transferred; e.g., liquid coolants, fuels and lubricants, slurry solutions, high explosives in past form, etc. The coupled partial differential equations are determined for the lateral motion of a spinning Bernoulli-Euler beam or a spinning cable carrying an incompressible flowing fluid. The beam, which spins about an axis parallel to its longitudinal axis and which can also be loaded by a constant axial force, is straight, uniform, simply supported, and rests on a massless, uniform elastic foundation. Damping for the beam and foundation is considered by using a combined uniform viscous damping coefficient. The fluid, in addition to being incompressible, is frictionless, has a constant density, and flows at a constant speed relative to the longitudinal beam axis. The Galerkin method is used to reduce the coupled partial differential equations for the lateral motion of the spinning beam to a coupled set of 2N, second order, ordinary differential equations for the generalized beam coordinates. By simplifying these equations and examining the roots of the characteristic equation, an analytical solution is obtained for the lateral dynamic instability of the beam or cable. The analytical solutions determine the critical fluid speed and the critical spin speeds, for a specified fluid speed, in terms of the physical parameters of the system
Modeling of Dynamic Fluid Forces in Fast Switching Valves
DEFF Research Database (Denmark)
Roemer, Daniel Beck; Johansen, Per; Pedersen, Henrik Clemmensen
2015-01-01
history term. For general valve geometries there are no simple solution to either of these terms. During development and design of such switching valves, it is therefore, common practice to use simple models to describe the opposing fluid forces, neglecting all but the viscous term which is determined...... force, but these models are computationally expensive and are not suitable for evaluating large numbers of different operation conditions or even design optimization. In the present paper, an effort is done to describe these fluid forces and their origin. An example of the total opposing fluid force...... the opposing fluid force well and gives accurate predictions under certain conditions. The proposed model is suitable for valve designers who need a computationally inexpensive fluid force model suitable for optimization routines or efficient dynamic models....
Nonlinear transport processes and fluid dynamics: Cylindrical Couette flow of Lennard-Jones fluids
International Nuclear Information System (INIS)
Khayat, R.E.; Eu, B.C.
1988-01-01
In this paper we report on calculations of flow profiles for cylindrical Couette flow of a Lennard-Jones fluid. The flow is subjected to a temperature gradient and thermoviscous effects are taken into consideration. We apply the generalized fluid dynamic equations which are provided by the modified moment method for the Boltzmann equation reported previously. The results of calculations are in good agreement with the Monte Carlo direct simulation method by K. Nanbu [Phys. Fluids 27, 2632 (1984)] for most of Knudsen numbers for which the simulation data are available
A dynamic neutral fluid model for the PIC scheme
Wu, Alan; Lieberman, Michael; Verboncoeur, John
2010-11-01
Fluid diffusion is an important aspect of plasma simulation. A new dynamic model is implemented using the continuity and boundary equations in OOPD1, an object oriented one-dimensional particle-in-cell code developed at UC Berkeley. The model is described and compared with analytical methods given in [1]. A boundary absorption parameter can be adjusted from ideal absorption to ideal reflection. Simulations exhibit good agreement with analytic time dependent solutions for the two ideal cases, as well as steady state solutions for mixed cases. For the next step, fluid sources and sinks due to particle-particle or particle-fluid collisions within the simulation volume and to surface reactions resulting in emission or absorption of fluid species will be implemented. The resulting dynamic interaction between particle and fluid species will be an improvement to the static fluid in the existing code. As the final step in the development, diffusion for multiple fluid species will be implemented. [4pt] [1] M.A. Lieberman and A.J. Lichtenberg, Principles of Plasma Discharges and Materials Processing, 2nd Ed, Wiley, 2005.
A Textbook for a First Course in Computational Fluid Dynamics
Zingg, D. W.; Pulliam, T. H.; Nixon, David (Technical Monitor)
1999-01-01
This paper describes and discusses the textbook, Fundamentals of Computational Fluid Dynamics by Lomax, Pulliam, and Zingg, which is intended for a graduate level first course in computational fluid dynamics. This textbook emphasizes fundamental concepts in developing, analyzing, and understanding numerical methods for the partial differential equations governing the physics of fluid flow. Its underlying philosophy is that the theory of linear algebra and the attendant eigenanalysis of linear systems provides a mathematical framework to describe and unify most numerical methods in common use in the field of fluid dynamics. Two linear model equations, the linear convection and diffusion equations, are used to illustrate concepts throughout. Emphasis is on the semi-discrete approach, in which the governing partial differential equations (PDE's) are reduced to systems of ordinary differential equations (ODE's) through a discretization of the spatial derivatives. The ordinary differential equations are then reduced to ordinary difference equations (O(Delta)E's) using a time-marching method. This methodology, using the progression from PDE through ODE's to O(Delta)E's, together with the use of the eigensystems of tridiagonal matrices and the theory of O(Delta)E's, gives the book its distinctiveness and provides a sound basis for a deep understanding of fundamental concepts in computational fluid dynamics.
Electron probe analysis of biological fluids: Possibilities and limitations
International Nuclear Information System (INIS)
Roinel, N.
1984-01-01
Physical methods of investigation have become essential to investigations at the cellular or subcellular level. Nuclear magnetic resonance is the most recent and striking example, since it is not only a tool for fundamental physicists and organic chemists, but also an extraordinary powerful imaging tool for physicians. The absorption properties of X rays were used immediately after their discovery to image the bones of skeletons. Later, X rays were also found to be extremely efficient in the measurement of the elemental content of microvolumes irradiated by electron probes. The electron probe analyzer (EPA) was immediately adopted by numerous laboratories of metallurgy, geology, and mineral sciences. In the last fifteen years, since the use of this instrument was suggested for liquid analysis, and a preparative technique was developed, the EPA has been used by an increasing number of biological laboratories for measuring the concentrations of the elements contained in subnanoliter volumes of biological fluids. The so-called microdroplet technique has become a routine laboratory method, the only one able to measure the concentrations of an unlimited number of elements in a single 0.1-nl sample. This explains its use in fields as various as renal, reproductive, digestive, and plant physiology, zoology, etc. Several review papers discuss these applications. The possibilities and limitations of the technique are discussed below
Obstructive renal injury: from fluid mechanics to molecular cell biology
Directory of Open Access Journals (Sweden)
Alvaro C Ucero
2010-04-01
Full Text Available Alvaro C Ucero1,*, Sara Gonçalves2,*, Alberto Benito-Martin1, Beatriz Santamaría1, Adrian M Ramos1, Sergio Berzal1, Marta Ruiz-Ortega1, Jesus Egido1, Alberto Ortiz11Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain; 2Nefrologia e Transplantação Renal, Hospital de Santa Maria EPE, Lisbon, Portugal *Both authors contributed equally to the manuscriptAbstract: Urinary tract obstruction is a frequent cause of renal impairment. The physiopathology of obstructive nephropathy has long been viewed as a mere mechanical problem. However, recent advances in cell and systems biology have disclosed a complex physiopathology involving a high number of molecular mediators of injury that lead to cellular processes of apoptotic cell death, cell injury leading to inflammation and resultant fibrosis. Functional studies in animal models of ureteral obstruction using a variety of techniques that include genetically modified animals have disclosed an important role for the renin-angiotensin system, transforming growth factor-β1 (TGF-β1 and other mediators of inflammation in this process. In addition, high throughput techniques such as proteomics and transcriptomics have identified potential biomarkers that may guide clinical decision-making.Keywords: urinary tract obstruction, renal injury, fluid mechanics, molecular cell biology
Dynamic fluid interface formation in microfluidics
Muijlwijk, Kelly; Li, Xuezhu; Berton-Carabin, Claire; Schroën, Karin
2018-01-01
Microfluidic devices are known for their accurate control of emulsification, but are less known for their suitability to investigate involved dynamic mechanisms. We previously showed that a microfluidic Y-junction can be used to measure interfacial tension in the millisecond time-scale, at high
F*** Yeah Fluid Dynamics: Getting started in science communication
Sharp, Nicole
2017-11-01
We live in an era of unprecedented opportunities for connecting with other scientists and with the public about our work, but taking the first steps into this wider world of science communication can be intimidating. This talk will focus on what researchers and students need to get started or to take their efforts to the next level. It will highlight some inspirational examples both within fluid dynamics and elsewhere, share lessons learned from fluid dynamics outreach blog FYFD, and provide current and future science communicators with valuable resources for developing their outreach.
Turn function and vorticity method for numerical fluid dynamics
International Nuclear Information System (INIS)
O'Rourke, P.J.
1984-01-01
A numerical method is presented that solves in a consistent fashion, conservation equations for both vorticity and linear momentum in multidimensional fluid-dynamics calculations. The equations are given in both two- and three-dimensional Cartesian geometry, and it is shown how the method can be easily implemented in a two-dimensional Eulerian fluid-dynamics code. The results of example calculations, which were performed with and without the new method, show the large errors that can arise when the vorticity equation is not solved in compressible flow calculations
Observations on the fluid aspects of magnetotail dynamics
International Nuclear Information System (INIS)
Lui, A.T.Y.
1987-01-01
Although the earth magnetotail consists of very rarefied plasmas, many global features of this region in space can be well described by fluid parameters rather than statistical quantities. Here a brief overview is given of present knowledge of a host of substorm phenomena as well as of nonsubstorm-related structures and dynamics in the magnetotail. Models of a substorm for the magnetotail are described and briefly commented on. Examples that indicate the limitations of fluid treatment of magnetotail dynamics are also discussed. 157 references
BMS3 invariant fluid dynamics at null infinity
Penna, Robert F.
2018-02-01
We revisit the boundary dynamics of asymptotically flat, three dimensional gravity. The boundary is governed by a momentum conservation equation and an energy conservation equation, which we interpret as fluid equations, following the membrane paradigm. We reformulate the boundary’s equations of motion as Hamiltonian flow on the dual of an infinite-dimensional, semi-direct product Lie algebra equipped with a Lie–Poisson bracket. This gives the analogue for boundary fluid dynamics of the Marsden–Ratiu–Weinstein formulation of the compressible Euler equations on a manifold, M, as Hamiltonian flow on the dual of the Lie algebra of \
Optics and fluid dynamics department annual progress report for 1992
International Nuclear Information System (INIS)
Lading, L.; Lynov, J.P.; Skaarup, B.
1993-01-01
Research in the Optics and FLuid Dynamics Department is performed within two sections. The Optics Section has activities within (a) optical materials, (b) quasielastic light scattering and diagnostics in solids, fluids and plasmas, and (c) optical and electronic information processing. The Continuum Physics Section performs (a) studies of nonlinear dynamical processes in continuum systems, (b) investigations of other problems in fusion plasma physics, and (c) develops pellet injectors for fusion experiments. Most of these activities are done in connection with the Euratom Association. A summary of activities in 1992 is presented. (au) (25 ills., 36 refs.)
2D fluid simulations of interchange turbulence with ion dynamics
DEFF Research Database (Denmark)
Nielsen, Anders Henry; Madsen, Jens; Xu, G. S.
2013-01-01
In this paper we present a first principle global two-dimensional fluid model. The HESEL (Hot Edge SOL Electrostatic) model is a 2D numerical fluid code, based on interchange dynamics and includes besides electron also the ion pressure dynamic. In the limit of cold ions the model almost reduces...... to the so-called ESEL model, which has successfully modeled profiles in JET [1], and profiles and fluctuations in MAST [2], EAST [3] and TCV [4]. It is a four-field Braginskii model including generalized vorticity, density, electron and ion pressure equations. The generalized vorticity consist of an Ex...
Thermo-Fluid Dynamics of Two-Phase Flow
Ishii, Mamrou
2011-01-01
"Thermo-fluid Dynamics of Two-Phase Flow, Second Edition" is focused on the fundamental physics of two-phase flow. The authors present the detailed theoretical foundation of multi-phase flow thermo-fluid dynamics as they apply to: Nuclear reactor transient and accident analysis; Energy systems; Power generation systems; Chemical reactors and process systems; Space propulsion; Transport processes. This edition features updates on two-phase flow formulation and constitutive equations and CFD simulation codes such as FLUENT and CFX, new coverage of the lift force model, which is of part
Archer, A J
2009-01-07
In recent years, a number of dynamical density functional theories (DDFTs) have been developed for describing the dynamics of the one-body density of both colloidal and atomic fluids. In the colloidal case, the particles are assumed to have stochastic equations of motion and theories exist for both the case when the particle motion is overdamped and also in the regime where inertial effects are relevant. In this paper, we extend the theory and explore the connections between the microscopic DDFT and the equations of motion from continuum fluid mechanics. In particular, starting from the Kramers equation, which governs the dynamics of the phase space probability distribution function for the system, we show that one may obtain an approximate DDFT that is a generalization of the Euler equation. This DDFT is capable of describing the dynamics of the fluid density profile down to the scale of the individual particles. As with previous DDFTs, the dynamical equations require as input the Helmholtz free energy functional from equilibrium density functional theory (DFT). For an equilibrium system, the theory predicts the same fluid one-body density profile as one would obtain from DFT. Making further approximations, we show that the theory may be used to obtain the mode coupling theory that is widely used for describing the transition from a liquid to a glassy state.
Equilibrium and nonequilibrium dynamics of soft sphere fluids.
Ding, Yajun; Mittal, Jeetain
2015-07-14
We use computer simulations to test the freezing-point scaling relationship between equilibrium transport coefficients (self-diffusivity, viscosity) and thermodynamic parameters for soft sphere fluids. The fluid particles interact via the inverse-power potential (IPP), and the particle softness is changed by modifying the exponent of the distance-dependent potential term. In the case of IPP fluids, density and temperature are not independent variables and can be combined to obtain a coupling parameter to define the thermodynamic state of the system. We find that the rescaled coupling parameter, based on its value at the freezing point, can approximately collapse the diffusivity and viscosity data for IPP fluids over a wide range of particle softness. Even though the collapse is far from perfect, the freezing-point scaling relationship provides a convenient and effective way to compare the structure and dynamics of fluid systems with different particle softness. We further show that an alternate scaling relationship based on two-body excess entropy can provide an almost perfect collapse of the diffusivity and viscosity data below the freezing transition. Next, we perform nonequilibrium molecular dynamics simulations to calculate the shear-dependent viscosity and to identify the distinct role of particle softness in underlying structural changes associated with rheological properties. Qualitatively, we find a similar shear-thinning behavior for IPP fluids with different particle softness, though softer particles exhibit stronger shear-thinning tendency. By investigating the distance and angle-dependent pair correlation functions in these systems, we find different structural features in the case of IPP fluids with hard-sphere like and softer particle interactions. Interestingly, shear-thinning in hard-sphere like fluids is accompanied by enhanced translational order, whereas softer fluids exhibit loss of order with shear. Our results provide a systematic evaluation
Pirbodaghi, Tohid; Vigolo, Daniele; Akbari, Samin; deMello, Andrew
2015-05-07
The widespread application of microfluidic devices in the biological and chemical sciences requires the implementation of complex designs and geometries, which in turn leads to atypical fluid dynamic phenomena. Accordingly, a complete understanding of fluid dynamics in such systems is key in the facile engineering of novel and efficient analytical tools. Herein, we present an accurate approach for studying the fluid dynamics of rapid processes within microfluidic devices using bright-field microscopy with white light illumination and a standard high-speed camera. Specifically, we combine Ghost Particle Velocimetry and the detection of moving objects in automated video surveillance to track submicron size tracing particles via cross correlation between the speckle patterns of successive images. The efficacy of the presented technique is demonstrated by measuring the flow field over a square pillar (80 μm × 80 μm) in a 200 μm wide microchannel at high volumetric flow rates. Experimental results are in excellent agreement with those obtained via computational fluid dynamics simulations. The method is subsequently used to study the dynamics of droplet generation at a flow focusing microfluidic geometry. A unique feature of the presented technique is the ability to perform velocimetry analysis of high-speed phenomena, which is not possible using micron-resolution particle image velocimetry (μPIV) approaches based on confocal or fluorescence microscopy.
Dynamics of polymeric liquids. Vol. 1, 2nd Ed.: Fluid mechanics
International Nuclear Information System (INIS)
Bird, R.B.; Armstrong, R.C.; Hassager, O.
1987-01-01
This book examines Newtonian liquids and polymer fluid mechanics. It begins with a review of the main ideas of fluid dynamics as well as key points of Newtonian fluids. Major revisions include extensive updating of all material and a greater emphasis on fluid dynamics problem solving. It presents summaries of experiments describing the difference between polymeric and simple fluids. In addition, it traces, roughly in historical order, various methods for solving polymer fluid dynamics problems
Cellular-automata supercomputers for fluid-dynamics modeling
International Nuclear Information System (INIS)
Margolus, N.; Toffoli, T.; Vichniac, G.
1986-01-01
We report recent developments in the modeling of fluid dynamics, and give experimental results (including dynamical exponents) obtained using cellular automata machines. Because of their locality and uniformity, cellular automata lend themselves to an extremely efficient physical realization; with a suitable architecture, an amount of hardware resources comparable to that of a home computer can achieve (in the simulation of cellular automata) the performance of a conventional supercomputer
Partial chemical equilibrium in fluid dynamics
International Nuclear Information System (INIS)
Ramshaw, J.D.
1980-01-01
An analysis is given for the flow of a multicomponent fluid in which an arbitrary number of chemical reactions may occur, some of which are in equilibrium while the others proceed kinetically. The primitive equations describing this situation are inconvenient to use because the progress rates omega-dot/sub s/ for the equilibrium reactions are determined implicitly by the associated equilibrium constraint conditions. Two alternative equivalent equation systems that are more pleasant to deal with are derived. In the first system, the omega-dot/sub s/ are eliminated by replacing the transport equations for the chemical species involved in the equilibrium reactions with transport equations for the basic components of which these species are composed. The second system retains the usual species transport equations, but eliminates the nonlinear algebraic equilibrium constraint conditions by deriving an explicit expression for the omega-dot/sub s/. Both systems are specialized to the case of an ideal gas mixture. Considerations involved in solving these equation systems numerically are discussed briefly
FLOWPLOT2, 2-D, 3-D Fluid Dynamic Plots
International Nuclear Information System (INIS)
Cobb, C.K.; Tunstall, J.N.
1989-01-01
1 - Description of program or function: FLOWPLOT2 is a plotting program used with numerical or analytical fluid dynamics codes to create velocity vector plots, contour plots of up to three fluid parameters (e.g. pressure, density, and temperature), two-dimensional profile plots, three-dimensional curve plots, and/or three-dimensional surface plots for either the u or v velocity components. If the fluid dynamics code computes a transient or simulated time related solution, FLOWPLOT2 can also be used to generate these plots for any specified time interval. Multiple cases generating different plots for different time intervals may be run in one execution of the program. In addition, plots can be created for selected two- dimensional planes of three-dimensional steady-state problems. The user has the option of producing plots on CalComp or Versatec plotters or microfiche and of creating a compressed dataset before plotting. 2 - Method of solution: FLOWPLOT2 reads a dataset written by the fluid dynamics code. This dataset must be written in a specified format and must contain parametric data at the nodal points of a uniform or non-uniform rectangular grid formed by the intersection of the grid lines of the model. 3 - Restrictions on the complexity of the problem - Maxima of: 2500 nodes, 40 y-values for 2-D profile plots and 3-D curve plots, 20 contour values, 3 fluid parameters
Dynamic analysis of multibody system immersed in a fluid medium
International Nuclear Information System (INIS)
Wu, R.W.; Liu, L.K.; Levy, S.
1977-01-01
This paper is concerned primarily with the development and evaluation of an analysis method for the reponse prediction of immersed systems to seismic and other dynamic excitations. For immersed multibody systems, the hydrodynamic interaction causes coupled motion among the solid bodies. Also, under intense external excitations, impact between bodies may occur. The complex character of such systems inhibit the use of conventional analytical solutions in closed form. Therefore, approximate numerical schemes have been devised. For an incompressible, inviscid fluid, the hydrodynamic forces exerted by the fluid on solid bodies are determined to be linearly proportional to the acceleration of the vibrating solid bodies; i.e., the presence of the fluid only affects the inertia of the solid body system. A finite element computer program has been developed for computing this hydrodynamic (or added) mass effect. This program can be used to determine the hydrodynamic mass of a two-dimensional fluid field with solid bodies of arbitrary geometry. Triangular elements and linear pressure interpolation function are used to discretize the fluid region. The component element method is used to determine the dynamic response of the multibody system to externally applied mechanical loading or support excitation. The present analysis method for predicting the dynamic response of submerged multibody system is quite general and pertains to any number of solid bodies. However in this paper, its application is demonstrated only for 4 and 25 body systems. (Auth.)
A Computational Fluid Dynamics Algorithm on a Massively Parallel Computer
Jespersen, Dennis C.; Levit, Creon
1989-01-01
The discipline of computational fluid dynamics is demanding ever-increasing computational power to deal with complex fluid flow problems. We investigate the performance of a finite-difference computational fluid dynamics algorithm on a massively parallel computer, the Connection Machine. Of special interest is an implicit time-stepping algorithm; to obtain maximum performance from the Connection Machine, it is necessary to use a nonstandard algorithm to solve the linear systems that arise in the implicit algorithm. We find that the Connection Machine ran achieve very high computation rates on both explicit and implicit algorithms. The performance of the Connection Machine puts it in the same class as today's most powerful conventional supercomputers.
Nonequilibrium chiral fluid dynamics including dissipation and noise
International Nuclear Information System (INIS)
Nahrgang, Marlene; Herold, Christoph; Bleicher, Marcus; Leupold, Stefan
2011-01-01
We present a consistent theoretical approach for the study of nonequilibrium effects in chiral fluid dynamics within the framework of the linear σ model with constituent quarks. Treating the quarks as an equilibrated heat bath, we use the influence functional formalism to obtain a Langevin equation for the σ field. This allows us to calculate the explicit form of the damping coefficient and the noise correlators. For a self-consistent derivation of both the dynamics of the σ field and the quark fluid, we have to employ the 2PI (two-particle irreducible) effective action formalism. The energy dissipation from the field to the fluid is treated in the exact formalism of the 2PI effective action where a conserved energy-momentum tensor can be constructed. We derive its form and comment on approximations generating additional terms in the energy-momentum balance of the entire system.
FLOWPLOT: a fluid dynamics and heat transfer plotting package
International Nuclear Information System (INIS)
Elrod, D.C.; Tunstall, J.N.
1978-03-01
The FLOWPLOT plotting program may be used with numerical fluid dynamics (or heat transfer with convection) codes to create velocity vector plots and/or contour plots of up to three fluid parameters (e.g. pressure, density, and temperature). FLOWPLOT reads a data set created by the user's fluid dynamics code. This data set must contain parametric data at every nodal point of a rectangular grid. FLOWPLOT uses the Display Integrated Software System and Plotting Language (DISSPLA). Therefore, the user has the option of creating the plot data set on CALCOMP tape or creating a compressed plot data set that may be input to the DISSPLA postprocessor. This program has been stored on disk at ORGDP on the IBM 360/370 computing system
Magnetohydrodynamics and fluid dynamics action principles and conservation laws
Webb, Gary
2018-01-01
This text focuses on conservation laws in magnetohydrodynamics, gasdynamics and hydrodynamics. A grasp of new conservation laws is essential in fusion and space plasmas, as well as in geophysical fluid dynamics; they can be used to test numerical codes, or to reveal new aspects of the underlying physics, e.g., by identifying the time history of the fluid elements as an important key to understanding fluid vorticity or in investigating the stability of steady flows. The ten Galilean Lie point symmetries of the fundamental action discussed in this book give rise to the conservation of energy, momentum, angular momentum and center of mass conservation laws via Noether’s first theorem. The advected invariants are related to fluid relabeling symmetries – so-called diffeomorphisms associated with the Lagrangian map – and are obtained by applying the Euler-Poincare approach to Noether’s second theorem. The book discusses several variants of helicity including kinetic helicity, cross helicity, magnetic helici...
International Nuclear Information System (INIS)
Sundaryanto, Bagus; Yortsos, Yanis C.
1999-01-01
In applications involving this injection of a fluid in a porous medium to displace another fluid, a main objective is the maximization of the displacement efficiency. For a fixed arrangement of injection and production points (sources and sinks), such optimization is possible by controlling the injection rate policy. Despite its practical relevance, however, this aspect has received scant attention in the literature. In this paper, a fundamental approach based on optimal control theory, for the case when the fluids are miscible, of equal viscosity and in the absence of dispersion and gravity effects. Both homogeneous and heterogeneous porous media are considered. From a fluid dynamics viewpoint, this is a problem in the deformation of material lines in porous media, as a function of time-varying injection rates
Lagrangian fluid dynamics using the Voronoi-Delauanay mesh
International Nuclear Information System (INIS)
Dukowicz, J.K.
1981-01-01
A Lagrangian technique for numerical fluid dynamics is described. This technique makes use of the Voronoi mesh to efficiently locate new neighbors, and it uses the dual (Delaunay) triangulation to define computational cells. This removes all topological restrictions and facilitates the solution of problems containing interfaces and multiple materials. To improve computational accuracy a mesh smoothing procedure is employed
Computational Fluid Dynamics and Building Energy Performance Simulation
DEFF Research Database (Denmark)
Nielsen, Peter V.; Tryggvason, Tryggvi
An interconnection between a building energy performance simulation program and a Computational Fluid Dynamics program (CFD) for room air distribution will be introduced for improvement of the predictions of both the energy consumption and the indoor environment. The building energy performance...
Modelling Emission from Building Materials with Computational Fluid Dynamics
DEFF Research Database (Denmark)
Topp, Claus; Nielsen, Peter V.; Heiselberg, Per
This paper presents a numerical model that by means of computational fluid dynamics (CFD) is capable of dealing with both pollutant transport across the boundary layer and internal diffusion in the source without prior knowledge of which is the limiting process. The model provides the concentration...
Prospects for Computational Fluid Dynamics in Room Air Contaminant Control
DEFF Research Database (Denmark)
Nielsen, Peter V.
The fluid dynamics research is strongly influenced by the increasing computer power which has been available for the last decades. This development is obvious from the curve in figure 1 which shows the computation cost as a function of years. It is obvious that the cost for a given job...
Computational Fluid Dynamics and Building Energy Performance Simulation
DEFF Research Database (Denmark)
Nielsen, Peter Vilhelm; Tryggvason, T.
1998-01-01
An interconnection between a building energy performance simulation program and a Computational Fluid Dynamics program (CFD) for room air distribution will be introduced for improvement of the predictions of both the energy consumption and the indoor environment. The building energy performance...
Computational fluid dynamics using in vivo ultrasound blood flow measurements
DEFF Research Database (Denmark)
Traberg, Marie Sand; Pedersen, Mads Møller; Hemmsen, Martin Christian
2012-01-01
This paper presents a model environment for construction of patient-specific computational fluid dynamic (CFD) models for the abdominal aorta (AA). Realistic pulsatile velocity waveforms are employed by using in vivo ultrasound blood flow measurements. Ultrasound is suitable for acquisition...
Mathematical and physical problems in nuclear fluid dynamics
International Nuclear Information System (INIS)
Agodi, A.; Di Toro, M.
1985-01-01
A biased and personal view is presented on the main motivations and results in this area of nuclear research discussed during the workshop on ''Fluid Dynamical Approaches to the Many Body Problem: Fundamental and Mathematical Aspects'', held in Catania from 9 to 11 April 1984
Computational fluid dynamics in greenhouses: A review | De la ...
African Journals Online (AJOL)
Computational fluid dynamics is a tool that has been used in recent years to develop numerical models that improve our understanding of the interaction of variables that make up the climate inside greenhouses. In the past five years, more realistic studies have appeared due mainly to the development of more powerful ...
Application of computational fluid dynamics modelling to an ozone ...
African Journals Online (AJOL)
Computational fluid dynamics (CFD) modelling has been applied to examine the operation of the pre-ozonation system at Wiggins Waterworks, operated by Umgeni Water in Durban, South Africa. A hydraulic model has been satisfactorily verified by experimental tracer tests. The turbulence effect induced by the gas ...
Direct visualization of fluid dynamics in sub-10 nm nanochannels.
Li, Huawei; Zhong, Junjie; Pang, Yuanjie; Zandavi, Seyed Hadi; Persad, Aaron Harrinarine; Xu, Yi; Mostowfi, Farshid; Sinton, David
2017-07-13
Optical microscopy is the most direct method to probe fluid dynamics at small scales. However, contrast between fluid phases vanishes at ∼10 nm lengthscales, limiting direct optical interrogation to larger systems. Here, we present a method for direct, high-contrast and label-free visualization of fluid dynamics in sub-10 nm channels, and apply this method to study capillary filling dynamics at this scale. The direct visualization of confined fluid dynamics in 8-nm high channels is achieved with a conventional bright-field optical microscope by inserting a layer of a high-refractive-index material, silicon nitride (Si 3 N 4 ), between the substrate and the nanochannel, and the height of which is accurately controlled down to a few nanometers by a SiO 2 spacer layer. The Si 3 N 4 layer exhibits a strong Fabry-Perot resonance in reflection, providing a sharp contrast between ultrathin liquid and gas phases. In addition, the Si 3 N 4 layer enables robust anodic bonding without nanochannel collapse. With this method, we demonstrate the validity of the classical Lucas-Washburn equation for capillary filling in the sub-10 nm regime, in contrast to the previous studies, for both polar and nonpolar liquids, and for aqueous salt solutions.
Microchannel Emulsification: From Computational Fluid Dynamics to Predictive Analytical Model
Dijke, van K.C.; Schroën, C.G.P.H.; Boom, R.M.
2008-01-01
Emulsion droplet formation was investigated in terrace-based microchannel systems that generate droplets through spontaneous Laplace pressure driven snap-off. The droplet formation mechanism was investigated through high-speed imaging and computational fluid dynamics (CFD) simulation, and we found
Theoretical approaches to chemical dynamics in highly compressed fluids
International Nuclear Information System (INIS)
Calef, D.F.
1987-01-01
Methods that have been developed in the chemical physics community over the previous decade are applied to problems involving the dynamic chemical behavior of fluids under highly compressed conditions. The methods require detailed structural information about the environment seen by the reacting molecules. These methods are briefly reviewed. Examples for both statically compressed and shock conditions are discussed
Fluid dynamical approach to spinodal instabilities in finite nuclear systems
International Nuclear Information System (INIS)
Jacquot, B.; Chomaz, Ph.; Ayik, S.; Colonna, M.
1996-04-01
The growth of instabilities of finite nuclear systems at low densities is investigated using a fluid dynamical approach. For a sufficiently large source several multiple modes up to an ultraviolet cut-off become unstable with nearly the same growth rate, indicating that the system may develop towards different fragmentation channels with nearly equal probability. (author)
Computational fluid dynamics (CFD) simulation of hot air flow ...
African Journals Online (AJOL)
Computational Fluid Dynamics simulation of air flow distribution, air velocity and pressure field pattern as it will affect moisture transient in a cabinet tray dryer is performed using SolidWorks Flow Simulation (SWFS) 2014 SP 4.0 program. The model used for the drying process in this experiment was designed with Solid ...
A Physically-Motivated Deformable Model Based on Fluid Dynamics
Jalba, Andrei C.; Roerdink, Jos B.T.M.; Leonardis, A; Bischof, H; Pinz, A
2006-01-01
A novel deformable model for image segmentation and shape recovery is presented. The model is inspired by fluid dynamics and is based on a flooding simulation similar to the watershed paradigm. Unlike most watershed methods, our model has a continuous formulation, being described by two partial
Dynamic analysis of multibody system immersed in a fluid medium
International Nuclear Information System (INIS)
Wu, R.W.; Liu, L.K.; Levy, S.
1977-01-01
This paper is concerned primarily with the development and evaluation of an analysis method for the response prediction of immersed multibody systems to seismic and other dynamic excitations. For immersed multibody systems to seismic and other dynamic excitations. For immersed multibody systems, the hydrodynamic interaction causes coupled motion among the solid bodies. Also, under intense external excitations, impact between bodies may occur. The complex character of such systems inhibit the use of conventional analytical solutions in closed form. Therefore, approximate numerical schemes have been devised. For an incompressible, inviscid fluid, the hydrodynamic forces exerted by the fluid on solid bodies are determined to be linearly proportional to the acceleration of the vibrating solid bodies; i.e., the presence of the fluid only affects the inertia of the solid body system. A finite element computer program has been developed for computing this hydrodynamic (or added) mass effect. This program can be used to determine the hydrodynamic mass of a two-dimensional fluid field with solid bodies of arbitrary geometry. Triangular elements and linear pressure interpolation function are used to discretize the fluid region. The component element method is used to determine the dynamic response of the multibody system to externally applied mechanical loading or support excitation. In the component element method, each structural body is modeled by component elements of conceptual spring-damper type. This method is particularly advantageous for systems having nonlinearities. Direct timewise numerical integration scheme is used to solve the governing dynamic equation of the system. Analytical study is carried out and compared with an experimental result for the forced vibration of 4 simply supported beams in water. Also studied is a case of 25 (5x5) beams within a square fluid-filled container by using two different approaches
Dynamic Modeling of ThermoFluid Systems
DEFF Research Database (Denmark)
Jensen, Jakob Munch
2003-01-01
The objective of the present study has been to developed dynamic models for two-phase flow in pipes (evaporation and condensation). Special attention has been given to modeling evaporators for refrigeration plant particular dry-expansion evaporators. Models of different complexity have been...... formulated. The different models deviate with respect to the detail¿s included and calculation time in connection with simulation. The models have been implemented in a new library named ThermoTwoPhase to the programming language Modelica. A test rig has been built with an evaporator instrumented in a way...... that the models can be validated against experimental data. The models developed van be used in connection with intelligent control of refrigerant flow to dry-expansion evaporators....
Unsteady fluid dynamics around a hovering wing
Krishna, Swathi; Green, Melissa; Mulleners, Karen
2017-11-01
The unsteady flow around a hovering flat plate wing has been investigated experimentally using particle image velocimetry and direct force measurements. The measurements are conducted on a wing that rotates symmetrically about the stroke reversal at a reduced frequency of k = 0.32 and Reynolds number of Re = 220 . The Lagrangian finite-time Lyapunov exponent method is used to analyse the unsteady flow fields by identifying dynamically relevant flow features such as the primary leading edge vortex (LEV), secondary vortices, and topological saddles, and their evolution within a flapping cycle. The flow evolution is divided into four stages that are characterised by the LEV (a)emergence, (b)growth, (c)lift-off, and (d)breakdown and decay. Tracking saddle points is shown to be helpful in defining the LEV lift-off which occurs at the maximum stroke velocity. The flow fields are correlated with the aerodynamic forces revealing that the maximum lift and drag are observed just before LEV lift-off. The end of wing rotation in the beginning of the stroke stimulates a change in the direction of the LEV growth and the start of rotation at the end of the stroke triggers the breakdown of the LEV.
Fluctuations and Response in Geophysical Fluid Dynamics
Lucarini, Valerio
The climate is a complex, chaotic, non-equilibrium system featuring a limited horizon of predictability, variability on a vast range of temporal and spatial scales, instabilities resulting into energy transformations, and mixing and dissipative processes resulting into entropy production. Despite great progresses, we still do not have a complete theory of climate dynamics able to account for instabilities, equilibration processes, response to changing parameters of the system, and multiscale effects. We will outline some possible applications of the response theory developed by Ruelle for non-equilibrium statistical mechanical systems, showing how it allows for setting on firm ground and on a coherent framework concepts like climate sensitivity, climate response, and climate tipping points, and to construct parametrizations for unresolved processes. We will show results for comprehensive global climate models. The results are promising in terms of suggesting new ways for approaching the problem of climate change prediction and for using more efficiently the enormous amounts of data produced by modeling groups around the world. Ref: V. Lucarini, R. Blender, C. Herbert, F. Ragone, S. Pascale, J. Wouters, Mathematical and Physical Ideas for Climate Science, Reviews of Geophysics 52, 809-859 (2014)
Fluid-filled dynamic bowtie filter: a feasibility study
Shunhavanich, Picha; Hsieh, Scott S.; Pelc, Norbert J.
2015-03-01
By varying its thickness to compensate for the different path length through the patient as a function of fan angle, a pre-patient bowtie filter modulates flux distribution to reduce patient dose, scatter, and detector dynamic range, and to improve image quality. A dynamic bowtie filter is superior to its traditional, static counterpart in its ability to adjust its thickness along different fan and view angles to suit a specific patient and task. Among the proposed dynamic bowtie designs, the piecewise-linear and the digital beam attenuators offer more flexibility than conventional filters, but rely on analog positioning of a limited number of wedges. In this work, we introduce a new approach with digital control, called the fluid-filled dynamic bowtie filter. It is a two-dimensional array of small binary elements (channels filled or unfilled with attenuating liquid) in which the cumulative thickness along the x-ray path contributes to the bowtie's total attenuation. Using simulated data from a pelvic scan, the performance is compared with the piecewise-linear attenuator. The fluid-filled design better matches the desired target attenuation profile and delivers a 4.2x reduction in dynamic range. The variance of the reconstruction (or noise map) can also be more homogeneous. In minimizing peak variance, the fluid-filled attenuator shows a 3% improvement. From the initial simulation results, the proposed design has more control over the flux distribution as a function of both fan and view angles.
Heat transfer and fluid flow in biological processes advances and applications
Becker, Sid
2015-01-01
Heat Transfer and Fluid Flow in Biological Processes covers emerging areas in fluid flow and heat transfer relevant to biosystems and medical technology. This book uses an interdisciplinary approach to provide a comprehensive prospective on biofluid mechanics and heat transfer advances and includes reviews of the most recent methods in modeling of flows in biological media, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas. Heat Transfer and Fluid Flow in Biological Processes is an indispensable reference for professors, graduate students, professionals, and clinical researchers in the fields of biology, biomedical engineering, chemistry and medicine working on applications of fluid flow, heat transfer, and transport phenomena in biomedical technology. Provides a wide range of biological and clinical applications of fluid...
Yu, Alex; Jackson, Trachette; Tsume, Yasuhiro; Koenigsknecht, Mark; Wysocki, Jeffrey; Marciani, Luca; Amidon, Gordon L; Frances, Ann; Baker, Jason R; Hasler, William; Wen, Bo; Pai, Amit; Sun, Duxin
2017-11-01
Gastrointestinal (GI) fluid volume and its dynamic change are integral to study drug disintegration, dissolution, transit, and absorption. However, key questions regarding the local volume and its absorption, secretion, and transit remain unanswered. The dynamic fluid compartment absorption and transit (DFCAT) model is proposed to estimate in vivo GI volume and GI fluid transport based on magnetic resonance imaging (MRI) quantified fluid volume. The model was validated using GI local concentration of phenol red in human GI tract, which was directly measured by human GI intubation study after oral dosing of non-absorbable phenol red. The measured local GI concentration of phenol red ranged from 0.05 to 168 μg/mL (stomach), to 563 μg/mL (duodenum), to 202 μg/mL (proximal jejunum), and to 478 μg/mL (distal jejunum). The DFCAT model characterized observed MRI fluid volume and its dynamic changes from 275 to 46.5 mL in stomach (from 0 to 30 min) with mucus layer volume of 40 mL. The volumes of the 30 small intestine compartments were characterized by a max of 14.98 mL to a min of 0.26 mL (0-120 min) and a mucus layer volume of 5 mL per compartment. Regional fluid volumes over 0 to 120 min ranged from 5.6 to 20.38 mL in the proximal small intestine, 36.4 to 44.08 mL in distal small intestine, and from 42 to 64.46 mL in total small intestine. The DFCAT model can be applied to predict drug dissolution and absorption in the human GI tract with future improvements.
Symposium on computational fluid dynamics: technology and applications
International Nuclear Information System (INIS)
1988-01-01
A symposium on the technology and applications of computational fluid dynamics (CFD) was held in Pretoria from 21-23 Nov 1988. The following aspects were covered: multilevel adaptive methods and multigrid solvers in CFD, a symbolic processing approach to CFD, interplay between CFD and analytical approximations, CFD on a transfer array, the application of CFD in high speed aerodynamics, numerical simulation of laminar blood flow, two-phase flow modelling in nuclear accident analysis, and the finite difference scheme for the numerical solution of fluid flow
Computational fluid dynamics simulations of light water reactor flows
International Nuclear Information System (INIS)
Tzanos, C.P.; Weber, D.P.
1999-01-01
Advances in computational fluid dynamics (CFD), turbulence simulation, and parallel computing have made feasible the development of three-dimensional (3-D) single-phase and two-phase flow CFD codes that can simulate fluid flow and heat transfer in realistic reactor geometries with significantly reduced reliance, especially in single phase, on empirical correlations. The objective of this work was to assess the predictive power and computational efficiency of a CFD code in the analysis of a challenging single-phase light water reactor problem, as well as to identify areas where further improvements are needed
Krekelberg, William P; Siderius, Daniel W; Shen, Vincent K; Truskett, Thomas M; Errington, Jeffrey R
2017-08-03
Using molecular simulations, we investigate how the range of fluid-fluid (adsorbate-adsorbate) interactions and the strength of fluid-solid (adsorbate-adsorbent) interactions impact the strong connection between distinct adsorptive regimes and distinct self-diffusivity regimes reported in [Krekelberg, W. P.; Siderius, D. W.; Shen, V. K.; Truskett, T. M.; Errington, J. R. Langmuir 2013 , 29 , 14527-14535]. Although increasing the fluid-fluid interaction range changes both the thermodynamics and the dynamic properties of adsorbed fluids, the previously reported connection between adsorptive filling regimes and self-diffusivity regimes remains. Increasing the fluid-fluid interaction range leads to enhanced layering and decreased self-diffusivity in the multilayer-formation regime but has little effect on the properties within film-formation and pore-filling regimes. We also find that weakly attractive adsorbents, which do not display distinct multilayer formation, are hard-sphere-like at super- and subcritical temperatures. In this case, the self-diffusivity of the confined and bulk fluid has a nearly identical scaling-relationship with effective density.
Dynamic analysis of structures with solid-fluid interaction
International Nuclear Information System (INIS)
Nahavandi, A.N.; Pedrido, R.R.; Cloud, R.L.
1977-01-01
This study develops a finite element model for interaction between an elastic solid and fluid medium (flow-induced vibrations in nuclear reactor components). Plane triangular finite elements have been used separately for fluid, solid, and solid-fluid continuua and the equivalent mass, damping, and stiffness matrices and interaction load arrays for all elements are derived and assembled into global matrices. The global matrix differential equation of motion developed is solved in time to obtain the pressure and velocity distributions in the fluid, as well as the displacements in the solid. Two independent computer programs are used to obtain the dynamic solution. The first program is a finite element program developed for solid-fluid interaction studies. This program uses the modal superposition technique in which the eigenvalues and eigenvectors for the system are found and used to uncouple the equations. This approach allows an analytic solution in each integration time step. The second program is WECAN finite element program in which a new element library subroutine for solid-fluid interaction was incorporated. This program can employ a NASTRAN direct integration scheme based on a central difference formula for the acceleration and velocity terms and an implicit representation of the displacement term. This reduces the problem to a matrix equation whose right hand side is updated in every time step and is solved by a variation of the Gaussian elimination method known as the wave front technique. Results have been obtained for the case of water, between two flat elastic parallel plates, initially at rest and accelerated suddenly by applying a step pressure. The results obtained from the above-mentioned two independent finite element programs are in full agreement. This verification provides the confidence needed to initiate parametric studies. Both rigid wall (no solid-fluid interaction) and flexible wall (including solid-fluid interaction) cases were examined
Fluid-dynamic behavior of flaxseed fluidized and spouted bed
Directory of Open Access Journals (Sweden)
Elza Brandão Santana
2017-09-01
Full Text Available ABSTRACT: Processing of particles in a moving bed, such as a fluidized bed or a spouting bed, is commonly used in the operations of drying, coating, and granulation of particulate systems. This process has applications in the chemical, pharmaceutical and, presently, agronomical industries, especially for seed treatment/coating. This research aimed to analyze the fluid-dynamic behavior of fluidized and spouting beds with different air temperatures and loads of flaxseeds (Linum usitatissimum L., with estimates of the fluid-dynamic parameters correlated to each process. The parameters were compared with the values obtained from classical correlations in the literature, with indications of associated percentages of deviation. Influence of fluid dynamics on the physiological quality of seeds was assessed by germination tests and the germination speed index. An analysis of the results indicated that seed processing was adequate for processing in dynamically active beds; however, temperatures above 50ºC in both beds caused significant reductions in the physiological quality of the seeds. Processing in a fluidized bed presented a smaller reduction of the physiological properties of the flaxseed.
Particle hopping vs. fluid-dynamical models for traffic flow
Energy Technology Data Exchange (ETDEWEB)
Nagel, K.
1995-12-31
Although particle hopping models have been introduced into traffic science in the 19509, their systematic use has only started recently. Two reasons for this are, that they are advantageous on modem computers, and that recent theoretical developments allow analytical understanding of their properties and therefore more confidence for their use. In principle, particle hopping models fit between microscopic models for driving and fluiddynamical models for traffic flow. In this sense, they also help closing the conceptual gap between these two. This paper shows connections between particle hopping models and traffic flow theory. It shows that the hydrodynamical limits of certain particle hopping models correspond to the Lighthill-Whitham theory for traffic flow, and that only slightly more complex particle hopping models produce already the correct traffic jam dynamics, consistent with recent fluid-dynamical models for traffic flow. By doing so, this paper establishes that, on the macroscopic level, particle hopping models are at least as good as fluid-dynamical models. Yet, particle hopping models have at least two advantages over fluid-dynamical models: they straightforwardly allow microscopic simulations, and they include stochasticity.
Structure, biomimetics, and fluid dynamics of fish skin surfaces*
Lauder, George V.; Wainwright, Dylan K.; Domel, August G.; Weaver, James C.; Wen, Li; Bertoldi, Katia
2016-10-01
The interface between the fluid environment and the surface of the body in swimming fishes is critical for both physiological and hydrodynamic functions. The skin surface in most species of fishes is covered with bony scales or toothlike denticles (in sharks). Despite the apparent importance of fish surfaces for understanding aquatic locomotion and near-surface boundary layer flows, relatively little attention has been paid to either the nature of surface textures in fishes or possible hydrodynamic effects of variation in roughness around the body surface within an individual and among species. Fish surfaces are remarkably diverse and in many bony fishes scales can have an intricate surface texture with projections, ridges, and comblike extensions. Shark denticles (or scales) are toothlike and project out of the skin to form a complexly textured surface that interacts with free-stream flow. Manufacturing biomimetic foils with fishlike surfaces allows hydrodynamic testing and we emphasize here the importance of dynamic test conditions where the effect of surface textures is assessed under conditions of self-propulsion. We show that simple two-dimensional foils with patterned cuts do not perform as well as a smooth control surface, but that biomimetic shark skin foils can swim at higher self-propelled speeds than smooth controls. When the arrangement of denticles on the foil surface is altered, we find that a staggered-overlapped pattern outperforms other arrangements. Flexible foils made of real shark skin outperform sanded controls when foils are moved with a biologically realistic motion program. We suggest that focus on the mechanisms of drag reduction by fish surfaces has been too limiting and an additional role of fish surface textures may be to alter leading edge vortices and flow patterns on moving surfaces in a way that enhances thrust. Analysis of water flow over an artificial shark skin foil under both static and dynamic conditions shows that a shear layer
Dynamics of mixed convective-stably-stratified fluids
Couston, L.-A.; Lecoanet, D.; Favier, B.; Le Bars, M.
2017-09-01
We study the dynamical regimes of a density-stratified fluid confined between isothermal no-slip top and bottom boundaries (at temperatures Tt and Tb) via direct numerical simulation. The thermal expansion coefficient of the fluid is temperature dependent and chosen such that the fluid density is maximum at the inversion temperature Tb>Ti>Tt . Thus, the lower layer of the fluid is convectively unstable while the upper layer is stably stratified. We show that the characteristics of the convection change significantly depending on the degree of stratification of the stable layer. For strong stable stratification, the convection zone coincides with the fraction of the fluid that is convectively unstable (i.e., where T >Ti ), and convective motions consist of rising and sinking plumes of large density anomaly, as is the case in canonical Rayleigh-Bénard convection; internal gravity waves are generated by turbulent fluctuations in the convective layer and propagate in the upper layer. For weak stable stratification, we demonstrate that a large fraction of the stable fluid (i.e., with temperature T phenomenological description of the transition between the regimes of plume-dominated and entrainment-dominated convection through analysis of the differences in the heat transfer mechanisms, kinetic energy density spectra, and probability density functions for different stratification strengths. Importantly, we find that the effect of the stable layer on the convection decreases only weakly with increasing stratification strength, meaning that the dynamics of the stable layer and convection should be studied self-consistently in a wide range of applications.
Dynamics of linear polymers in a microchannel fluid flow
Bose, Prasenjit; Fodor, Petru; Kaufman, Miron
2010-10-01
Examination of the dynamics of polymers in a fluid flow is an important topic of research because of potential biomedical applications. We simulated the motion of a linear polymer caried in a laminar fluid flow inside a rectangular channel. Our model polymer is made up of beads which are connected by springs. When the polymer is released in the fluid elastic and advection forces act on each bead. The Newton's 2nd law for each bead is integrated numerically using 4th order Runge-Kutta technique. The dynamics of this nonlinear mechanical system depends on the values of the spring equilibrium distance (a), mass of a bead (m), the initial fluid inflow constant (B), and the spring constant (k). Various trials were conducted by varying some of these parameters and the results were recorded and plotted. It was observed that the motion of the polymer was more noisy for higher values of a and k. The variation of time periods with the changing parameters was studied numerically.
Lattice fluid dynamics from perfect discretizations of continuum flows
International Nuclear Information System (INIS)
Katz, E.; Wiese, U.
1998-01-01
We use renormalization group methods to derive equations of motion for large scale variables in fluid dynamics. The large scale variables are averages of the underlying continuum variables over cubic volumes and naturally exist on a lattice. The resulting lattice dynamics represents a perfect discretization of continuum physics, i.e., grid artifacts are completely eliminated. Perfect equations of motion are derived for static, slow flows of incompressible, viscous fluids. For Hagen-Poiseuille flow in a channel with a square cross section the equations reduce to a perfect discretization of the Poisson equation for the velocity field with Dirichlet boundary conditions. The perfect large scale Poisson equation is used in a numerical simulation and is shown to represent the continuum flow exactly. For nonsquare cross sections one can use a numerical iterative procedure to derive flow equations that are approximately perfect. copyright 1998 The American Physical Society
Fluid dynamics applications of the Illiac IV computer
Maccormack, R. W.; Stevens, K. G., Jr.
1976-01-01
The Illiac IV is a parallel-structure computer with computing power an order of magnitude greater than that of conventional computers. It can be used for experimental tasks in fluid dynamics which can be simulated more economically, for simulating flows that cannot be studied by experiment, and for combining computer and experimental simulations. The architecture of Illiac IV is described, and the use of its parallel operation is demonstrated on the example of its solution of the one-dimensional wave equation. For fluid dynamics problems, a special FORTRAN-like vector programming language was devised, called CFD language. Two applications are described in detail: (1) the determination of the flowfield around the space shuttle, and (2) the computation of transonic turbulent separated flow past a thick biconvex airfoil.
Optics and Fluid Dynamics Department annual progress report for 1993
International Nuclear Information System (INIS)
Hanson, S.G.; Lading, L.; Michelsen, P.; Skaarup, B.
1994-01-01
Research in the Optics and Fluid Dynamics Department is performed within the following two programme areas: optics and continuum physics. In optics the activities are within (a) optical materials, (b) quasi-elastic light scattering and diagnostics in solids, fluids, and plasmas, and (c) optical and electronic information processing. Within continuum physics the activities are within (a) studies of non-linear dynamical processes in continuum systems, (b) investigations of problems with relevance to fusion plasma physics. The injection of pellets in fusion experiments has been investigated and pellet injectors to European fusion experiments are manufactured. The department is also responsible for the EURATOM collaboration within fusion plasma physics. A summary of activities in 1993 is presented. (au) (27 ills., 24 refs.)
Contributions to thermal and fluid dynamic problems in nuclear technology
International Nuclear Information System (INIS)
Mueller, U.; Krebs, L.; Rust, K.
1984-02-01
The majority of contributions compiled in this report deals with thermal and fluid dynamic problems in nuclear engineering. Especially problems of heat transfer and cooling are represented which may arise during and afer a loss-of-coolant accident both in light water reactors and in liquid metal cooled fast breeder reactors. Papers on the mass transfer in pressurized water, tribological problems in sodium cooled reactors, the fluid dynamics of pulsed column, and fundamental investigations of convective flows supplement these contributions on problems connected with accidents. Furthermore, a keynote paper presents the individual activities relating to the reliability of reactor components, a field recently included in our research program. Technical solutions to special problems are closely connected to the investigations based on experiments. Therefore, several contributions deal with new developments in technology and measuring techniques. (orig.) [de
Optics and Fluid Dynamics Department annual progress report for 1996
Energy Technology Data Exchange (ETDEWEB)
Hanson, S.G.; Johansen, P.M.; Lading, L.; Lynov, J.P.; Skaarup, B. [eds.
1997-01-01
Research in the Optics and Fluid Dynamics Department has been performed within the following three programme areas: (1) optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The work is concentrated on combinations of systems, structures and materials. The systems work is focused on sensors, information processing an storage; the structures work is concentrated on pattern formation and diffractive elements; the materials work is centred on the understanding and utilisation of nonlinear phenomena. Scientific computing is an integral part of the work. The activities are supported by several EU programmes, including EURATOM, by research councils and by industry. A summary of the activities in 1996 is presented. (au) 53 ills., 232 refs.
Optics and Fluid Dynamics Department annual progress report for 1996
International Nuclear Information System (INIS)
Hanson, S.G.; Johansen, P.M.; Lading, L.; Lynov, J.P.; Skaarup, B.
1997-01-01
Research in the Optics and Fluid Dynamics Department has been performed within the following three programme areas: (1) optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The work is concentrated on combinations of systems, structures and materials. The systems work is focused on sensors, information processing an storage; the structures work is concentrated on pattern formation and diffractive elements; the materials work is centred on the understanding and utilisation of nonlinear phenomena. Scientific computing is an integral part of the work. The activities are supported by several EU programmes, including EURATOM, by research councils and by industry. A summary of the activities in 1996 is presented. (au) 53 ills., 232 refs
A computational fluid dynamic model for fluidized bed heat transfer
International Nuclear Information System (INIS)
Yusuf, R.; Melaaen, M.C.; Mathiesen, V.
2005-01-01
The objective of this work is to study heat transfer from a heated wall in a gas fluidized bed using the computational fluid dynamic (CFD) approach. An Eulerian-Eulerian simulation of a two dimensional bubbling bed at ambient conditions with a heated wall is carried out on the in-house code FLOTRACS-MP-3D. An empirical as well as a mechanistic model for solid phase thermal conductivity is tested. Effect of operating parameters like velocity and particle size are also investigated. The fluid dynamic model is able to predict the qualitative trends for the influence of operating parameters as well as high heat transfer coefficients observed in gas fluidized beds. (author)
The application of computational fluid dynamics to critical heat flux
International Nuclear Information System (INIS)
Stuhmiller, J.H.; Masiello, P.J.; Srikantiah, G.S.; Agee, L.J.
1995-01-01
The estimation of critical heat flux (CHF) in nuclear reactors is based largely on empirical relations that have a physical limiting conditions, a narrow range of applicability, and are inadequate for transient conditions. It is generally agreed that a more physically based approach is needed. Evidence is presented supporting the importance of boiling-induced fluid flow o the CHF process. Computational fluid dynamics (CFD) is used to model the microscale, transient dynamics of a vapor bubble growing in a subcooled liquid, resulting in qualitative reproduction of vapor blanket growth and CHF. The same CFD techniques are used to evaluate the macroscale thermal diffusion caused by spacers, resulting in qualitative reproduction of previous empirical results. This work forms the basis for a systematic investigation of CHF that could result in improved and less costly procedures for nuclear fuel design. This work is relevant for BWR and PWR reactors
Optics and Fluid Dynamics Department annual progress report for 1997
Energy Technology Data Exchange (ETDEWEB)
Hanson, S.G.; Johansen, P.M.; Lading, L.; Lynov, J.P.; Skaarup, B. [eds.
1998-04-01
Research in the Optics and Fluid Dynamics Department has been performed within the following three programme areas: (1) optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The work is concentrated on combinations of systems, structures and materials. The systems work is focused on sensors, information processing and storage; the structures work is concentrated on pattern formation and diffractive elements; the materials work is centred on the understanding and utilisation of nonlinear phenomena for optical components and systems. Scientific computing is an integral part of the work. Biomedical optics is a new activity and the work on polymer optics is enhanced considerably. The activities are supported by several EU programmes, including EURATOM, by research councils and by industry. A summary of the activities in 1997 is presented. (au) 1 tab., 63 ills., 249 refs.
Optics and Fluid Dynamics Department annual progress report for 1997
International Nuclear Information System (INIS)
Hanson, S.G.; Johansen, P.M.; Lading, L.; Lynov, J.P.; Skaarup, B.
1998-04-01
Research in the Optics and Fluid Dynamics Department has been performed within the following three programme areas: (1) optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The work is concentrated on combinations of systems, structures and materials. The systems work is focused on sensors, information processing and storage; the structures work is concentrated on pattern formation and diffractive elements; the materials work is centred on the understanding and utilisation of nonlinear phenomena for optical components and systems. Scientific computing is an integral part of the work. Biomedical optics is a new activity and the work on polymer optics is enhanced considerably. The activities are supported by several EU programmes, including EURATOM, by research councils and by industry. A summary of the activities in 1997 is presented. (au)
Basic Coandă MAV Fluid Dynamics and Flight Mechanics
Djojodihardjo, H.; Ahmed, RI
2017-04-01
Capitalizing on the basic fundamental principles, the Fluid Dynamics and Flight Mechanics of a semi-spherical Coandă MAV configurations are revisited and analyzed as a baseline. A mathematical model for a spherical Coandă MAV in hover and translatory motion is developed and analyzed from first physical principles. To gain further insight into the prevailing flow field around a Coandă MAV, as well as to verify the theoretical prediction presented in the work, a computational fluid dynamic CFD simulations for a Coandă MAV generic model are elaborated. The mathematical model and derived performance measures are shown to be capable in describing the physical phenomena of the flow field of the semi-spherical Coandă MAV. The relationships between the relevant parameters of the mathematical model of the Coandă MAV to the forces acting on it are elaborated subsequently.
Computational Fluid and Particle Dynamics in the Human Respiratory System
Tu, Jiyuan; Ahmadi, Goodarz
2013-01-01
Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researcher...
On the Schrodinger equation in fluid-dynamical form
International Nuclear Information System (INIS)
Wong, C.Y.
1976-01-01
The fluid-dynamical form of the Schrodinger equations is studied to examine the nature of the quantum forces arising from the quantum potential of Madelung and Bohm. It is found that they are in the form of a stress tensor having diagonal and nondiagonal components. Future studies of these quantum stress tensors in a many-body system may shed some light on the mechanism of spontaneous symmetry breaking and the generation of vorticity in many nuclear systems
Simulating soil melting with CFD [computational fluid dynamics
International Nuclear Information System (INIS)
Hawkes, G.L.
1997-01-01
Computational fluid dynamics (CFD) is being used to validate the use of thermal plasma arc vitrification for treatment of contaminated soil. Soil melting is modelled by a CFD calculation code which links electrical fields, heat transport, and natural convection. The developers believe it is the first successful CFD analysis to incorporate a simulated PID (proportional-integral-derivative) controller, which plays a vital role by following the specified electrical power curve. (Author)
Computational Fluid Dynamics. [numerical methods and algorithm development
1992-01-01
This collection of papers was presented at the Computational Fluid Dynamics (CFD) Conference held at Ames Research Center in California on March 12 through 14, 1991. It is an overview of CFD activities at NASA Lewis Research Center. The main thrust of computational work at Lewis is aimed at propulsion systems. Specific issues related to propulsion CFD and associated modeling will also be presented. Examples of results obtained with the most recent algorithm development will also be presented.
Dipole torus mode in nuclear fluid-dynamics
International Nuclear Information System (INIS)
Bastrukov, S.I.; Misicu, S.; Sushkov, A.V.
1992-01-01
The nuclear fluid-dynamics is applied to the study of a dipole electric response related to the transverse poloidal oscillations of a particle flow. This response is associated with excitation in the nucleus volume of the spherical Hill vortex - toruslike current structure harmonically oscillating in time; the nucleus shape remains to be spherical. Some hints for futher experiments are suggested. 42 refs.; 3 figs
Assessment of underwater glider performance through viscous computational fluid dynamics
Lidtke, Artur Konrad; Turnock, Stephen; Downes, Jon
2016-01-01
The process of designing an apt hydrodynamic shape for a new underwater glider is discussed. Intermediate stages include selecting a suitable axi-symmetric hull shape, adding hydrofoils and appendages, and evaluating the performance of the final design. All of the hydrodynamic characteristics are obtained using computational fluid dynamics using the kT - kL - ω transition model. It is shown that drag reduction of the main glider hull is of crucial importance to the ultimate performance. Sugge...
DYNAMICS OF FLUID IN OSCILLATORY FLOW: THE Z COMPONENT
Directory of Open Access Journals (Sweden)
V. C. -C. LEE
2015-10-01
Full Text Available In an oscillatory flow, the resistance to flow, more appropriately defined as the impedance to flow, is a function of oscillating frequency, which refers to the harmonic composition of the driving pressure wave. Flow in an elastic tube may be resisted in numerous ways such as the fluid viscosity, fluid inertia and tube elasticity. The concept of impedance arises in the dynamics of the ResistanceInductance-Capacitance. In oscillating flow, these represent the fluid viscosity, inertia and tube elasticity. This paper describes the effects of impedance, or the Z component as described in-text of an oscillating flow in a valveless impedance pump using numerical simulation. A one-dimensional lumpedsystem model is chosen to perform the analysis in this study. The simulation domain is a mimic to known experimental model previously conducted by Lee et.al. [18-21]. Impedance-induced flow has shown to be combined effects of fluid viscosity, inertia and tube elasticity. Results presented are in reasonable agreement with experimental results presented in Ref [21] with an estimate of 16% variance. This simple model has shown to predict results with significant values, using simple approximations; and further the understanding of fluid impedance’s role in a valveless impedance pump.
Fluid dynamics following flow shut-off in bottle filling
Thete, Sumeet; Appathurai, Santosh; Gao, Haijing; Basaran, Osman
2012-11-01
Bottle filling is ubiquitous in industry. Examples include filling of bottles with shampoos and cleaners, engine oil and pharmaceuticals. In these examples, fluid flows out of a nozzle to fill bottles in an assembly line. Once the required volume of fluid has flowed out of the nozzle, the flow is shut off. However, an evolving fluid thread or string may remain suspended from the nozzle following flow shut-off and persist. This stringing phenomenon can be detrimental to a bottle filling operation because it can adversely affect line speed and filling accuracy by causing uncertainty in fill volume, product loss and undesirable marring of the bottles' exterior surfaces. The dynamics of stringing are studied numerically primarily by using the 1D, slender-jet approximation of the flow equations. A novel feature entails development and use of a new boundary condition downstream of the nozzle exit to expedite the computations. While the emphasis is on stringing of Newtonian fluids and use of 1D approximations, results will also be presented for situations where (a) the fluids are non-Newtonian and (b) the full set of equations are solved without invoking the 1D approximation. Phase diagrams will be presented that identify conditions for which stringing can be problematic.
Optics and fluid dynamics department annual progress report for 1994
International Nuclear Information System (INIS)
Hanson, S.G.; Lading, L.; Lynov, J.P.; Michelsen, P.
1995-01-01
Research in the Optics and Fluid Dynamics Department is performed within the following two programme areas: optics and continuum physics. In optics the activities are within (a) optical materials and electromagnetic propagation, (b) diagnostics and sensors, and (c) information processing. In continuum physics the activities are (a) nonlinear dynamics and (b) computer physics. The activities are supported by several EU programmes, including EURATOM, by research councils, and by industry. A special activity is the implementation of pellet injectors for fusion research. A summary of activities in 1994 is presented. (au) (27 ills., 44 refs.)
Optics and fluid dynamics department annual progress report for 1994
Energy Technology Data Exchange (ETDEWEB)
Hanson, S.G.; Lading, L.; Lynov, J.P.; Michelsen, P.
1995-01-01
Research in the Optics and Fluid Dynamics Department is performed within the following two programme areas: optics and continuum physics. In optics the activities are within (a) optical materials and electromagnetic propagation, (b) diagnostics and sensors, and (c) information processing. In continuum physics the activities are (a) nonlinear dynamics and (b) computer physics. The activities are supported by several EU programmes, including EURATOM, by research councils, and by industry. A special activity is the implementation of pellet injectors for fusion research. A summary of activities in 1994 is presented. (au) (27 ills., 44 refs.).
Effect of centrifugation on dynamic susceptibility of magnetic fluids
Pshenichnikov, Alexander; Lebedev, Alexander; Lakhtina, Ekaterina; Kuznetsov, Andrey
2017-06-01
The dispersive composition, dynamic susceptibility and spectrum of times of magnetization relaxation for six samples of magnetic fluid obtained by centrifuging two base colloidal solutions of the magnetite in kerosene was investigated experimentally. The base solutions differed by the concentration of the magnetic phase and the width of the particle size distribution. The procedure of cluster analysis allowing one to estimate the characteristic sizes of aggregates with uncompensated magnetic moments was described. The results of the magnetogranulometric and cluster analyses were discussed. It was shown that centrifugation has a strong effect on the physical properties of the separated fractions, which is related to the spatial redistribution of particles and multi-particle aggregates. The presence of aggregates in magnetic fluids is interpreted as the main reason of low-frequency (0.1-10 kHz) dispersion of the dynamic susceptibility. The obtained results count in favor of using centrifugation as an effective means of changing the dynamic susceptibility over wide limits and obtaining fluids with the specified type of susceptibility dispersion.
A numerical model for dynamic crustal-scale fluid flow
Sachau, Till; Bons, Paul; Gomez-Rivas, Enrique; Koehn, Daniel
2015-04-01
Fluid flow in the crust is often envisaged and modeled as continuous, yet minimal flow, which occurs over large geological times. This is a suitable approximation for flow as long as it is solely controlled by the matrix permeability of rocks, which in turn is controlled by viscous compaction of the pore space. However, strong evidence (hydrothermal veins and ore deposits) exists that a significant part of fluid flow in the crust occurs strongly localized in both space and time, controlled by the opening and sealing of hydrofractures. We developed, tested and applied a novel computer code, which considers this dynamic behavior and couples it with steady, Darcian flow controlled by the matrix permeability. In this dual-porosity model, fractures open depending on the fluid pressure relative to the solid pressure. Fractures form when matrix permeability is insufficient to accommodate fluid flow resulting from compaction, decompression (Staude et al. 2009) or metamorphic dehydration reactions (Weisheit et al. 2013). Open fractures can close when the contained fluid either seeps into the matrix or escapes by fracture propagation: mobile hydrofractures (Bons, 2001). In the model, closing and sealing of fractures is controlled by a time-dependent viscous law, which is based on the effective stress and on either Newtonian or non-Newtonian viscosity. Our simulations indicate that the bulk of crustal fluid flow in the middle to lower upper crust is intermittent, highly self-organized, and occurs as mobile hydrofractures. This is due to the low matrix porosity and permeability, combined with a low matrix viscosity and, hence, fast sealing of fractures. Stable fracture networks, generated by fluid overpressure, are restricted to the uppermost crust. Semi-stable fracture networks can develop in an intermediate zone, if a critical overpressure is reached. Flow rates in mobile hydrofractures exceed those in the matrix porosity and fracture networks by orders of magnitude
77 FR 64834 - Computational Fluid Dynamics Best Practice Guidelines for Dry Cask Applications
2012-10-23
... NUCLEAR REGULATORY COMMISSION [NRC-2012-0250] Computational Fluid Dynamics Best Practice... public comments on draft NUREG-2152, ``Computational Fluid Dynamics Best Practice Guidelines for Dry Cask... opportunity to review and solicit comments on the draft NUREG-2152, ``Computational Fluid Dynamics Best...
Computational fluid dynamics study of viscous fingering in supercritical fluid chromatography.
Subraveti, Sai Gokul; Nikrityuk, Petr; Rajendran, Arvind
2018-01-26
Axi-symmetric numerical simulations are carried out to study the dynamics of a plug introduced through a mixed-stream injection in supercritical fluid chromatographic columns. The computational fluid dynamics model developed in this work takes into account both the hydrodynamics and adsorption equilibria to describe the phenomena of viscous fingering and plug effect that contribute to peak distortions in mixed-stream injections. The model was implemented into commercial computational fluid dynamics software using user-defined functions. The simulations describe the propagation of both the solute and modifier highlighting the interplay between the hydrodynamics and plug effect. The simulated peaks showed good agreement with experimental data published in the literature involving different injection volumes (5 μL, 50 μL, 1 mL and 2 mL) of flurbiprofen on Chiralpak AD-H column using a mobile phase of CO 2 and methanol. The study demonstrates that while viscous fingering is the main source of peak distortions for large-volume injections (1 mL and 2 mL) it has negligible impact on small-volume injections (5 μL and 50 μL). Band broadening in small-volume injections arise mainly due to the plug effect. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.
Use of self-actuating and self-sensing cantilevers for imaging biological samples in fluid.
Fantner, G E; Schumann, W; Barbero, R J; Deutschinger, A; Todorov, V; Gray, D S; Belcher, A M; Rangelow, I W; Youcef-Toumi, K
2009-10-28
In this paper, we present a detailed investigation into the suitability of atomic force microscopy (AFM) cantilevers with integrated deflection sensor and micro-actuator for imaging of soft biological samples in fluid. The Si cantilevers are actuated using a micro-heater at the bottom end of the cantilever. Sensing is achieved through p-doped resistors connected in a Wheatstone bridge. We investigated the influence of the water on the cantilever dynamics, the actuation and the sensing mechanisms, as well as the crosstalk between sensing and actuation. Successful imaging of yeast cells in water using the integrated sensor and actuator shows the potential of the combination of this actuation and sensing method. This constitutes a major step towards the automation and miniaturization required to establish AFM in routine biomedical diagnostics and in vivo applications.
Wavelet analysis of polarization maps of polycrystalline biological fluids networks
Ushenko, Y. A.
2011-12-01
The optical model of human joints synovial fluid is proposed. The statistic (statistic moments), correlation (autocorrelation function) and self-similar (Log-Log dependencies of power spectrum) structure of polarization two-dimensional distributions (polarization maps) of synovial fluid has been analyzed. It has been shown that differentiation of polarization maps of joint synovial fluid with different physiological state samples is expected of scale-discriminative analysis. To mark out of small-scale domain structure of synovial fluid polarization maps, the wavelet analysis has been used. The set of parameters, which characterize statistic, correlation and self-similar structure of wavelet coefficients' distributions of different scales of polarization domains for diagnostics and differentiation of polycrystalline network transformation connected with the pathological processes, has been determined.
Computational and analytical methods in nonlinear fluid dynamics
Walker, James
1993-09-01
The central focus of the program was on the application and development of modern analytical and computational methods to the solution of nonlinear problems in fluid dynamics and reactive gas dynamics. The research was carried out within the Division of Engineering Mathematics in the Department of Mechanical Engineering and Mechanics and principally involved Professors P.A. Blythe, E. Varley and J.D.A. Walker. In addition. the program involved various international collaborations. Professor Blythe completed work on reactive gas dynamics with Professor D. Crighton FRS of Cambridge University in the United Kingdom. Professor Walker and his students carried out joint work with Professor F.T. Smith, of University College London, on various problems in unsteady flow and turbulent boundary layers.
Issues in computational fluid dynamics code verification and validation
Energy Technology Data Exchange (ETDEWEB)
Oberkampf, W.L.; Blottner, F.G.
1997-09-01
A broad range of mathematical modeling errors of fluid flow physics and numerical approximation errors are addressed in computational fluid dynamics (CFD). It is strongly believed that if CFD is to have a major impact on the design of engineering hardware and flight systems, the level of confidence in complex simulations must substantially improve. To better understand the present limitations of CFD simulations, a wide variety of physical modeling, discretization, and solution errors are identified and discussed. Here, discretization and solution errors refer to all errors caused by conversion of the original partial differential, or integral, conservation equations representing the physical process, to algebraic equations and their solution on a computer. The impact of boundary conditions on the solution of the partial differential equations and their discrete representation will also be discussed. Throughout the article, clear distinctions are made between the analytical mathematical models of fluid dynamics and the numerical models. Lax`s Equivalence Theorem and its frailties in practical CFD solutions are pointed out. Distinctions are also made between the existence and uniqueness of solutions to the partial differential equations as opposed to the discrete equations. Two techniques are briefly discussed for the detection and quantification of certain types of discretization and grid resolution errors.
Serro, A P; Saramago, B
2003-11-01
The aim of this work was to investigate the effect of the sterilization processes on the mineralization of titanium implants induced by incubation in various biological model fluids. Titanium samples were submitted to the following sterilization processes used for implant materials: steam autoclaving, glow discharge Ar plasma treatment and gamma-irradiation. The modification of the treated surfaces was evaluated by contact angle determinations, X-ray photoelectron spectroscopy (XPS), laser profilometry and X-ray diffraction. The most significant modifications were detected on the wettability: while the samples treated with Ar plasma became highly hydrophilic (water contact angle approximately 0 degrees), gamma-irradiation and steam sterilization induced an increase in the hydrophobicity. After being sterilized, the samples were incubated for one week in three biological model fluids: Hanks' Balanced Salt Solution, Kokubo's simulated body fluid (SBF) and a fluid, designated by SBF0, with the same composition of SBF but without buffer TRIS. The level of mineralization of the incubated Ti samples, assessed by dynamic contact angle analysis, scanning electron microscopy, electron dispersive spectroscopy and XPS, indicated that the early stages of mineralization are essentially independent of the sterilization method. In contrast, the incubating fluid plays a determinant role, SBFO being the most efficient medium for biomineralization of titanium.
Moon, Ji Young; Suh, Dae Chul; Lee, Yong Sang; Kim, Young Woo; Lee, Joon Sang
2014-02-01
Despite recent development of computational fluid dynamics (CFD) research, analysis of computational fluid dynamics of cerebral vessels has several limitations. Although blood is a non-Newtonian fluid, velocity and pressure fields were computed under the assumptions of incompressible, laminar, steady-state flows and Newtonian fluid dynamics. The pulsatile nature of blood flow is not properly applied in inlet and outlet boundaries. Therefore, we present these technical limitations and discuss the possible solution by comparing the theoretical and computational studies.
Fluid dynamics parallel computer development at NASA Langley Research Center
Townsend, James C.; Zang, Thomas A.; Dwoyer, Douglas L.
1987-01-01
To accomplish more detailed simulations of highly complex flows, such as the transition to turbulence, fluid dynamics research requires computers much more powerful than any available today. Only parallel processing on multiple-processor computers offers hope for achieving the required effective speeds. Looking ahead to the use of these machines, the fluid dynamicist faces three issues: algorithm development for near-term parallel computers, architecture development for future computer power increases, and assessment of possible advantages of special purpose designs. Two projects at NASA Langley address these issues. Software development and algorithm exploration is being done on the FLEX/32 Parallel Processing Research Computer. New architecture features are being explored in the special purpose hardware design of the Navier-Stokes Computer. These projects are complementary and are producing promising results.
Data Point Averaging for Computational Fluid Dynamics Data
Norman, Jr., David (Inventor)
2016-01-01
A system and method for generating fluid flow parameter data for use in aerodynamic heating analysis. Computational fluid dynamics data is generated for a number of points in an area on a surface to be analyzed. Sub-areas corresponding to areas of the surface for which an aerodynamic heating analysis is to be performed are identified. A computer system automatically determines a sub-set of the number of points corresponding to each of the number of sub-areas and determines a value for each of the number of sub-areas using the data for the sub-set of points corresponding to each of the number of sub-areas. The value is determined as an average of the data for the sub-set of points corresponding to each of the number of sub-areas. The resulting parameter values then may be used to perform an aerodynamic heating analysis.
FAST - A multiprocessed environment for visualization of computational fluid dynamics
International Nuclear Information System (INIS)
Bancroft, G.V.; Merritt, F.J.; Plessel, T.C.; Kelaita, P.G.; Mccabe, R.K.
1991-01-01
The paper presents the Flow Analysis Software Toolset (FAST) to be used for fluid-mechanics analysis. The design criteria for FAST including the minimization of the data path in the computational fluid-dynamics (CFD) process, consistent user interface, extensible software architecture, modularization, and the isolation of three-dimensional tasks from the application programmer are outlined. Each separate process communicates through the FAST Hub, while other modules such as FAST Central, NAS file input, CFD calculator, surface extractor and renderer, titler, tracer, and isolev might work together to generate the scene. An interprocess communication package making it possible for FAST to operate as a modular environment where resources could be shared among different machines as well as a single host is discussed. 20 refs
Distributed interactive graphics applications in computational fluid dynamics
International Nuclear Information System (INIS)
Rogers, S.E.; Buning, P.G.; Merritt, F.J.
1987-01-01
Implementation of two distributed graphics programs used in computational fluid dynamics is discussed. Both programs are interactive in nature. They run on a CRAY-2 supercomputer and use a Silicon Graphics Iris workstation as the front-end machine. The hardware and supporting software are from the Numerical Aerodynamic Simulation project. The supercomputer does all numerically intensive work and the workstation, as the front-end machine, allows the user to perform real-time interactive transformations on the displayed data. The first program was written as a distributed program that computes particle traces for fluid flow solutions existing on the supercomputer. The second is an older post-processing and plotting program modified to run in a distributed mode. Both programs have realized a large increase in speed over that obtained using a single machine. By using these programs, one can learn quickly about complex features of a three-dimensional flow field. Some color results are presented
Fast reactor safety and computational thermo-fluid dynamics approaches
International Nuclear Information System (INIS)
Ninokata, Hisashi; Shimizu, Takeshi
1993-01-01
This article provides a brief description of the safety principle on which liquid metal cooled fast breeder reactors (LMFBRs) is based and the roles of computations in the safety practices. A number of thermohydraulics models have been developed to date that successfully describe several of the important types of fluids and materials motion encountered in the analysis of postulated accidents in LMFBRs. Most of these models use a mixture of implicit and explicit numerical solution techniques in solving a set of conservation equations formulated in Eulerian coordinates, with special techniques included to specific situations. Typical computational thermo-fluid dynamics approaches are discussed in particular areas of analyses of the physical phenomena relevant to the fuel subassembly thermohydraulics design and that involve describing the motion of molten materials in the core over a large scale. (orig.)
FAST - A multiprocessed environment for visualization of computational fluid dynamics
Bancroft, Gordon V.; Merritt, Fergus J.; Plessel, Todd C.; Kelaita, Paul G.; Mccabe, R. Kevin
1991-01-01
The paper presents the Flow Analysis Software Toolset (FAST) to be used for fluid-mechanics analysis. The design criteria for FAST including the minimization of the data path in the computational fluid-dynamics (CFD) process, consistent user interface, extensible software architecture, modularization, and the isolation of three-dimensional tasks from the application programmer are outlined. Each separate process communicates through the FAST Hub, while other modules such as FAST Central, NAS file input, CFD calculator, surface extractor and renderer, titler, tracer, and isolev might work together to generate the scene. An interprocess communication package making it possible for FAST to operate as a modular environment where resources could be shared among different machines as well as a single host is discussed.
Computational Fluid Dynamics (CFD) simulations of a Heisenberg Vortex Tube
Bunge, Carl; Sitaraman, Hariswaran; Leachman, Jake
2017-11-01
A 3D Computational Fluid Dynamics (CFD) simulation of a Heisenberg Vortex Tube (HVT) is performed to estimate cooling potential with cryogenic hydrogen. The main mechanism driving operation of the vortex tube is the use of fluid power for enthalpy streaming in a highly turbulent swirl in a dual-outlet tube. This enthalpy streaming creates a temperature separation between the outer and inner regions of the flow. Use of a catalyst on the peripheral wall of the centrifuge enables endothermic conversion of para-ortho hydrogen to aid primary cooling. A κ- ɛ turbulence model is used with a cryogenic, non-ideal equation of state, and para-orthohydrogen species evolution. The simulations are validated with experiments and strategies for parametric optimization of this device are presented.
Cardioplegia heat exchanger design modelling using computational fluid dynamics.
van Driel, M R
2000-11-01
A new cardioplegia heat exchanger has been developed by Sorin Biomedica. A three-dimensional computer-aided design (CAD) model was optimized using computational fluid dynamics (CFD) modelling. CFD optimization techniques have commonly been applied to velocity flow field analysis, but CFD analysis was also used in this study to predict the heat exchange performance of the design before prototype fabrication. The iterative results of the optimization and the actual heat exchange performance of the final configuration are presented in this paper. Based on the behaviour of this model, both the water and blood fluid flow paths of the heat exchanger were optimized. The simulation predicted superior heat exchange performance using an optimal amount of energy exchange surface area, reducing the total contact surface area, the device priming volume and the material costs. Experimental results confirm the empirical results predicted by the CFD analysis.
Fluid mechanics and heat transfer advances in nonlinear dynamics modeling
Asli, Kaveh Hariri
2015-01-01
This valuable new book focuses on new methods and techniques in fluid mechanics and heat transfer in mechanical engineering. The book includes the research of the authors on the development of optimal mathematical models and also uses modern computer technology and mathematical methods for the analysis of nonlinear dynamic processes. It covers technologies applicable to both fluid mechanics and heat transfer problems, which include a combination of physical, mechanical, and thermal techniques. The authors develop a new method for the calculation of mathematical models by computer technology, using parametric modeling techniques and multiple analyses for mechanical system. The information in this book is intended to help reduce the risk of system damage or failure. Included are sidebar discussions, which contain information and facts about each subject area that help to emphasize important points to remember.
Volume and density changes of biological fluids with temperature
Hinghofer-Szalkay, H.
1985-01-01
The thermal expansion of human blood, plasma, ultrafiltrate, and erythrocycte concentration at temperatures in the range of 4-48 C is studied. The mechanical oscillator technique which has an accuracy of 1 x 10 to the -5 th g/ml is utilized to measure fluid density. The relationship between thermal expansion, density, and temperature is analyzed. The study reveals that: (1) thermal expansion increases with increasing temperature; (2) the magnitude of the increase declines with increasing temperature; (3) thermal expansion increases with density at temperatures below 40 C; and (4) the thermal expansion of intracellular fluid is greater than that of extracellular fluid in the temperature range of 4-10 C, but it is equal at temperatures greater than or equal to 40 C.
Modeling fires in adjacent ship compartments with computational fluid dynamics
International Nuclear Information System (INIS)
Wix, S.D.; Cole, J.K.; Koski, J.A.
1998-01-01
This paper presents an analysis of the thermal effects on radioactive (RAM) transportation packages with a fire in an adjacent compartment. An assumption for this analysis is that the adjacent hold fire is some sort of engine room fire. Computational fluid dynamics (CFD) analysis tools were used to perform the analysis in order to include convective heat transfer effects. The analysis results were compared to experimental data gathered in a series of tests on tile US Coast Guard ship Mayo Lykes located at Mobile, Alabama
Computational fluid dynamics in fire engineering theory, modelling and practice
Yuen, Kwok Kit
2009-01-01
Fire and combustion presents a significant engineering challenge to mechanical, civil and dedicated fire engineers, as well as specialists in the process and chemical, safety, buildings and structural fields. We are reminded of the tragic outcomes of 'untenable' fire disasters such as at King's Cross underground station or Switzerland's St Gotthard tunnel. In these and many other cases, computational fluid dynamics (CFD) is at the forefront of active research into unravelling the probable causes of fires and helping to design structures and systems to ensure that they are less likely in the f
Quality control of computational fluid dynamics in indoor environments
DEFF Research Database (Denmark)
Sørensen, Dan Nørtoft; Nielsen, P. V.
2003-01-01
Computational fluid dynamics (CFD) is used routinely to predict air movement and distributions of temperature and concentrations in indoor environments. Modelling and numerical errors are inherent in such studies and must be considered when the results are presented. Here, we discuss modelling...... aspects of turbulence and boundary conditions, as well as aspects related to numerical errors, with emphasis on choice of differencing scheme and computational grid. Illustrative examples are given to stress the main points related to numerical errors. Finally, recommendations are given for improving...
Approaching multiphase flows from the perspective of computational fluid dynamics
International Nuclear Information System (INIS)
Banas, A.O.
1992-01-01
Thermalhydraulic simulation methodologies based on subchannel and porous-medium concepts are briefly reviewed and contrasted with the general approach of Computational Fluid Dynamics (CFD). An outline of the advanced CFD methods for single-phase turbulent flows is followed by a short discussion of the unified formulation of averaged equations for turbulent and multiphase flows. Some of the recent applications of CFD at Chalk River Laboratories are discussed, and the complementary role of CFD with regard to the established thermalhydraulic methods of analysis is indicated. (author). 8 refs
Torque converter transient characteristics prediction using computational fluid dynamics
International Nuclear Information System (INIS)
Yamaguchi, T; Tanaka, K
2012-01-01
The objective of this research is to investigate the transient torque converter performance used in an automobile. A new technique in computational fluid dynamics is introduced, which includes the inertia of the turbine in a three dimensional simulation of the torque converter during a launch condition. The simulation results are compared to experimental test data with good agreement across the range of data. In addition, the simulated flow structure inside the torque converter is visualized and compared to results from a steady-state calculation.
Morphing-Based Shape Optimization in Computational Fluid Dynamics
Rousseau, Yannick; Men'Shov, Igor; Nakamura, Yoshiaki
In this paper, a Morphing-based Shape Optimization (MbSO) technique is presented for solving Optimum-Shape Design (OSD) problems in Computational Fluid Dynamics (CFD). The proposed method couples Free-Form Deformation (FFD) and Evolutionary Computation, and, as its name suggests, relies on the morphing of shape and computational domain, rather than direct shape parameterization. Advantages of the FFD approach compared to traditional parameterization are first discussed. Then, examples of shape and grid deformations by FFD are presented. Finally, the MbSO approach is illustrated and applied through an example: the design of an airfoil for a future Mars exploration airplane.
Relativistic nuclear fluid dynamics and VUU kinetic theory
International Nuclear Information System (INIS)
Molitoris, J.J.; Hahn, D.; Alonso, C.; Collazo, I.; D'Alessandris, P.; McAbee, T.; Wilson, J.; Zingman, J.
1987-01-01
Relativistic kinetic theory may be used to understand hot dense hadronic matter. We address the questions of collective flow and pion production in a 3 D relativistic fluid dynamic model and in the VUU microscopic theory. The GSI/LBL collective flow and pion data point to a stiff equation of state. The effect of the nuclear equation of state on the thermodynamic parameters is discussed. The properties of dense hot hadronic matter are studied in Au + Au collisions from 0.1 to 10 GeV/nucleon. 22 refs., 5 figs
Continuing Validation of Computational Fluid Dynamics for Supersonic Retropropulsion
Schauerhamer, Daniel Guy; Trumble, Kerry A.; Kleb, Bil; Carlson, Jan-Renee; Edquist, Karl T.
2011-01-01
A large step in the validation of Computational Fluid Dynamics (CFD) for Supersonic Retropropulsion (SRP) is shown through the comparison of three Navier-Stokes solvers (DPLR, FUN3D, and OVERFLOW) and wind tunnel test results. The test was designed specifically for CFD validation and was conducted in the Langley supersonic 4 x4 Unitary Plan Wind Tunnel and includes variations in the number of nozzles, Mach and Reynolds numbers, thrust coefficient, and angles of orientation. Code-to-code and code-to-test comparisons are encouraging and possible error sources are discussed.
Fluid dynamic interaction between water hammer and centrifugal pumps
International Nuclear Information System (INIS)
Ismaier, A.; Schluecker, E.
2009-01-01
Centrifugal pumps generate in piping systems noticeable pressure pulsations. In this paper the dynamic interaction between water hammer and pressure pulsations is presented. The experimental investigations were performed at a piping system with nominal diameter DN 100 (respectively NPS 4) and 75 m total length, built at the Institute for Process Technology and Machinery. Different measurements at this testing facility show that pulsating centrifugal pumps can damp pressure surges generated by fast valve closing. It is also shown that 1-dimensional fluid codes can be used to calculate this phenomenon. Furthermore it is presented that pressure surges pass centrifugal pumps almost unhindered, because they are hydraulic open.
Computational Fluid Dynamics in Torque Converters: Validation and Application
Schweitzer, Jean; Gandham, Jeya
2003-01-01
This article describes some of the computational fluid dynamics (CFD) work being done on three-element torque converters using a commercially available package CFX TASCflow. The article details some of the work done to validate CFD results and gives examples of ways in which CFD is used in the torque-converter design process. Based on the validation study, it is shown that CFD can be used as a design and analysis tool to make decisions about design direction. Use of CFD in torque converters i...
Multitasking the code ARC3D. [for computational fluid dynamics
Barton, John T.; Hsiung, Christopher C.
1986-01-01
The CRAY multitasking system was developed in order to utilize all four processors and sharply reduce the wall clock run time. This paper describes the techniques used to modify the computational fluid dynamics code ARC3D for this run and analyzes the achieved speedup. The ARC3D code solves either the Euler or thin-layer N-S equations using an implicit approximate factorization scheme. Results indicate that multitask processing can be used to achieve wall clock speedup factors of over three times, depending on the nature of the program code being used. Multitasking appears to be particularly advantageous for large-memory problems running on multiple CPU computers.
Computational evaluation of convection schemes in fluid dynamics problems
Directory of Open Access Journals (Sweden)
Paulo Laerte Natti
2012-11-01
Full Text Available This article provides a computational evaluation of the popular high resolution upwind WACEB, CUBISTA and ADBQUICKEST schemes for solving non-linear fluid dynamics problems. By using the finite difference methodology, the schemes are analyzed and implemented in the context of normalized variables of Leonard. In order to access the performance of the schemes, Riemann problems for 1D Burgers, Euler and shallow water equations are considered. From the numerical results, the schemes are ranked according to their performance in solving these non-linear equations. The best scheme is then applied in the numerical simulation of tridimensional incompressible moving free surface flows.
Computational Fluid Dynamics Simulation of Fluidized Bed Polymerization Reactors
Energy Technology Data Exchange (ETDEWEB)
Fan, Rong [Iowa State Univ., Ames, IA (United States)
2006-01-01
Fluidized beds (FB) reactors are widely used in the polymerization industry due to their superior heat- and mass-transfer characteristics. Nevertheless, problems associated with local overheating of polymer particles and excessive agglomeration leading to FB reactors defluidization still persist and limit the range of operating temperatures that can be safely achieved in plant-scale reactors. Many people have been worked on the modeling of FB polymerization reactors, and quite a few models are available in the open literature, such as the well-mixed model developed by McAuley, Talbot, and Harris (1994), the constant bubble size model (Choi and Ray, 1985) and the heterogeneous three phase model (Fernandes and Lona, 2002). Most these research works focus on the kinetic aspects, but from industrial viewpoint, the behavior of FB reactors should be modeled by considering the particle and fluid dynamics in the reactor. Computational fluid dynamics (CFD) is a powerful tool for understanding the effect of fluid dynamics on chemical reactor performance. For single-phase flows, CFD models for turbulent reacting flows are now well understood and routinely applied to investigate complex flows with detailed chemistry. For multiphase flows, the state-of-the-art in CFD models is changing rapidly and it is now possible to predict reasonably well the flow characteristics of gas-solid FB reactors with mono-dispersed, non-cohesive solids. This thesis is organized into seven chapters. In Chapter 2, an overview of fluidized bed polymerization reactors is given, and a simplified two-site kinetic mechanism are discussed. Some basic theories used in our work are given in detail in Chapter 3. First, the governing equations and other constitutive equations for the multi-fluid model are summarized, and the kinetic theory for describing the solid stress tensor is discussed. The detailed derivation of DQMOM for the population balance equation is given as the second section. In this section
Dynamics of mathematical models in biology bringing mathematics to life
Zazzu, Valeria; Guarracino, Mario
2016-01-01
This volume focuses on contributions from both the mathematics and life science community surrounding the concepts of time and dynamicity of nature, two significant elements which are often overlooked in modeling process to avoid exponential computations. The book is divided into three distinct parts: dynamics of genomes and genetic variation, dynamics of motifs, and dynamics of biological networks. Chapters included in dynamics of genomes and genetic variation analyze the molecular mechanisms and evolutionary processes that shape the structure and function of genomes and those that govern genome dynamics. The dynamics of motifs portion of the volume provides an overview of current methods for motif searching in DNA, RNA and proteins, a key process to discover emergent properties of cells, tissues, and organisms. The part devoted to the dynamics of biological networks covers networks aptly discusses networks in complex biological functions and activities that interpret processes in cells. Moreover, chapters i...
International Nuclear Information System (INIS)
Delassalle, A.; Jacque, C.; Raoul, M.; Legrand, J.C.; Cesselin, F.; Drouet, J.
1980-01-01
The radioimmunoassay (RIA) for myelin basic protein (MBP) in biological fluids was reassessed in order to improve its sensitivity and eliminate some interferences. By using the pre-incubation technique and the charcoal-dextram-horse serum mixture for the separation step, the detection limit could be lowered to 200 pg/ml for cerebrospinal fluids (CSF), amniotic fluids (AF) and nervous tissue extracts and 600 pg/ml for sera. The RIA could be used directly on CSF, AF and nervous tissue extracts. Sera, however, had to be heated in citrate buffer at 100 0 C in order to discard interfering material. The present method is 10 to 20 times more sensitive than others previously published. Moreover, it can be applied to amniotic fluid. The biological fluids had to be promptly frozen to avoid degradation of MBP
Phase portrait methods for verifying fluid dynamic simulations
Energy Technology Data Exchange (ETDEWEB)
Stewart, H.B.
1989-01-01
As computing resources become more powerful and accessible, engineers more frequently face the difficult and challenging engineering problem of accurately simulating nonlinear dynamic phenomena. Although mathematical models are usually available, in the form of initial value problems for differential equations, the behavior of the solutions of nonlinear models is often poorly understood. A notable example is fluid dynamics: while the Navier-Stokes equations are believed to correctly describe turbulent flow, no exact mathematical solution of these equations in the turbulent regime is known. Differential equations can of course be solved numerically, but how are we to assess numerical solutions of complex phenomena without some understanding of the mathematical problem and its solutions to guide us
Application of Control Volume Analysis to Cerebrospinal Fluid Dynamics
Wei, Timothy; Cohen, Benjamin; Anor, Tomer; Madsen, Joseph
2011-11-01
Hydrocephalus is among the most common birth defects and may not be prevented nor cured. Afflicted individuals face serious issues, which at present are too complicated and not well enough understood to treat via systematic therapies. This talk outlines the framework and application of a control volume methodology to clinical Phase Contrast MRI data. Specifically, integral control volume analysis utilizes a fundamental, fluid dynamics methodology to quantify intracranial dynamics within a precise, direct, and physically meaningful framework. A chronically shunted, hydrocephalic patient in need of a revision procedure was used as an in vivo case study. Magnetic resonance velocity measurements within the patient's aqueduct were obtained in four biomedical state and were analyzed using the methods presented in this dissertation. Pressure force estimates were obtained, showing distinct differences in amplitude, phase, and waveform shape for different intracranial states within the same individual. Thoughts on the physiological and diagnostic research and development implications/opportunities will be presented.
Parallel Multiscale Algorithms for Astrophysical Fluid Dynamics Simulations
Norman, Michael L.
1997-01-01
Our goal is to develop software libraries and applications for astrophysical fluid dynamics simulations in multidimensions that will enable us to resolve the large spatial and temporal variations that inevitably arise due to gravity, fronts and microphysical phenomena. The software must run efficiently on parallel computers and be general enough to allow the incorporation of a wide variety of physics. Cosmological structure formation with realistic gas physics is the primary application driver in this work. Accurate simulations of e.g. galaxy formation require a spatial dynamic range (i.e., ratio of system scale to smallest resolved feature) of 104 or more in three dimensions in arbitrary topologies. We take this as our technical requirement. We have achieved, and in fact, surpassed these goals.
Relativistic Fluid Dynamics: Physics for Many Different Scales
Directory of Open Access Journals (Sweden)
Comer Gregory L.
2007-01-01
Full Text Available The relativistic fluid is a highly successful model used to describe the dynamics of many-particle, relativistic systems. It takes as input basic physics from microscopic scales and yields as output predictions of bulk, macroscopic motion. By inverting the process, an understanding of bulk features can lead to insight into physics on the microscopic scale. Relativistic fluids have been used to model systems as “small” as heavy ions in collisions, and as large as the Universe itself, with “intermediate” sized objects like neutron stars being considered along the way. The purpose of this review is to discuss the mathematical and theoretical physics underpinnings of the relativistic (multiple fluid model. We focus on the variational principle approach championed by Brandon Carter and his collaborators, in which a crucial element is to distinguish the momenta that are conjugate to the particle number density currents. This approach differs from the “standard” text-book derivation of the equations of motion from the divergence of the stress-energy tensor in that one explicitly obtains the relativistic Euler equation as an “integrability” condition on the relativistic vorticity. We discuss the conservation laws and the equations of motion in detail, and provide a number of (in our opinion interesting and relevant applications of the general theory.
Fluid Dynamics And Mass Transfer In Two-Fluid Taylor-Couette Flow
International Nuclear Information System (INIS)
Baier, G.; Graham, M.D.
1998-01-01
The Taylor-Couette instability of a single liquid phase can be used to enhance mass transfer processes such as filtration and membrane separations. We consider here the possibility of using this instability to enhance interphase transport in a two-fluid systems, with a view toward improved liquid-liquid extractions for biotechnology applications. We investigate the centrifugal instability of a pair of radially stratified immiscible liquids in the annular gap between concentric, corotating cylinders: two-fluid Taylor-Couette flow. Experiments show that a two-layer flow with a well-defined interface and Taylor vortices in each phase can be obtained. The experimental results are in good agreement with predictions of inviscid arguments based on a two-phase extension of Rayleigh's criterion, as well as with detailed linear stability calculations. For a given geometry, the most stable configuration occurs for fluids of roughly (exactly in the inviscid limit) equal dynamic viscosities. A number of preliminary mass transfer experiments have also been performed, in the presence of axial counterflow. The onset of Taylor vortices coincides with a clear decrease in the extent of axial dispersion and an increase in the rate of interphase transport, thus suggesting that this flow geometry may provide an effective means for countercurrent chromatographic separations
Computational Fluid Dynamics (CFD) Technology Programme 1995- 1999
Energy Technology Data Exchange (ETDEWEB)
Haekkinen, R.J.; Hirsch, C.; Krause, E.; Kytoemaa, H.K. [eds.
1997-12-31
The report is a mid-term evaluation of the Computational Fluid Dynamics (CFD) Technology Programme started by Technology Development Centre Finland (TEKES) in 1995 as a five-year initiative to be concluded in 1999. The main goal of the programme is to increase the know-how and application of CFD in Finnish industry, to coordinate and thus provide a better basis for co-operation between national CFD activities and encouraging research laboratories and industry to establish co-operation with the international CFD community. The projects of the programme focus on the following areas: (1) studies of modeling the physics and dynamics of the behaviour of fluid material, (2) expressing the physical models in a numerical mode and developing a computer codes, (3) evaluating and testing current physical models and developing new ones, (4) developing new numerical algorithms, solvers, and pre- and post-processing software, and (5) applying the new computational tools to problems relevant to their ultimate industrial use. The report consists of two sections. The first considers issues concerning the whole programme and the second reviews each project
High-performance holographic technologies for fluid-dynamics experiments
Orlov, Sergei S.; Abarzhi, Snezhana I.; Oh, Se Baek; Barbastathis, George; Sreenivasan, Katepalli R.
2010-01-01
Modern technologies offer new opportunities for experimentalists in a variety of research areas of fluid dynamics. Improvements are now possible in the state-of-the-art in precision, dynamic range, reproducibility, motion-control accuracy, data-acquisition rate and information capacity. These improvements are required for understanding complex turbulent flows under realistic conditions, and for allowing unambiguous comparisons to be made with new theoretical approaches and large-scale numerical simulations. One of the new technologies is high-performance digital holography. State-of-the-art motion control, electronics and optical imaging allow for the realization of turbulent flows with very high Reynolds number (more than 107) on a relatively small laboratory scale, and quantification of their properties with high space–time resolutions and bandwidth. In-line digital holographic technology can provide complete three-dimensional mapping of the flow velocity and density fields at high data rates (over 1000 frames per second) over a relatively large spatial area with high spatial (1–10 μm) and temporal (better than a few nanoseconds) resolution, and can give accurate quantitative description of the fluid flows, including those of multi-phase and unsteady conditions. This technology can be applied in a variety of problems to study fundamental properties of flow–particle interactions, rotating flows, non-canonical boundary layers and Rayleigh–Taylor mixing. Some of these examples are discussed briefly. PMID:20211881
Computational Fluid Dynamics Analysis of High Injection Pressure Blended Biodiesel
Khalid, Amir; Jaat, Norrizam; Faisal Hushim, Mohd; Manshoor, Bukhari; Zaman, Izzuddin; Sapit, Azwan; Razali, Azahari
2017-08-01
Biodiesel have great potential for substitution with petrol fuel for the purpose of achieving clean energy production and emission reduction. Among the methods that can control the combustion properties, controlling of the fuel injection conditions is one of the successful methods. The purpose of this study is to investigate the effect of high injection pressure of biodiesel blends on spray characteristics using Computational Fluid Dynamics (CFD). Injection pressure was observed at 220 MPa, 250 MPa and 280 MPa. The ambient temperature was kept held at 1050 K and ambient pressure 8 MPa in order to simulate the effect of boost pressure or turbo charger during combustion process. Computational Fluid Dynamics were used to investigate the spray characteristics of biodiesel blends such as spray penetration length, spray angle and mixture formation of fuel-air mixing. The results shows that increases of injection pressure, wider spray angle is produced by biodiesel blends and diesel fuel. The injection pressure strongly affects the mixture formation, characteristics of fuel spray, longer spray penetration length thus promotes the fuel and air mixing.
Computational fluid dynamic modeling of two passive samplers
International Nuclear Information System (INIS)
Thomas, Justin; Holsen, Thomas M.; Dhaniyala, Suresh
2006-01-01
To effectively use a passive sampler for monitoring trace contaminants in the gas-phase, its sampling characteristics as a function of ambient wind conditions must be known. In this study two commonly used passive samplers were evaluated using computational fluid dynamics. Contaminant uptake by the polyurethane foam (PUF) was modeled using a species transport model. The external-internal flow interactions in the sampler were characterized, and the uptake rates of contaminant species were quantified. The simulations show that flow fields in the samplers have strong velocity gradients, and single-point velocity measurements do not capture flow interactions accurately. Sampling rates calculated for a PUF in freestream are in good agreement with sampling rates for PUFs in the passive samplers studied for the same average velocity over the PUF. The calculated sampling rates are in general agreement with those obtained experimentally by other researchers. - The effect of wind speed on sampling rates of two commonly used passive samplers was investigated using computational fluid dynamic techniques
Computational fluid dynamic modeling of fluidized-bed polymerization reactors
Energy Technology Data Exchange (ETDEWEB)
Rokkam, Ram [Iowa State Univ., Ames, IA (United States)
2012-01-01
Polyethylene is one of the most widely used plastics, and over 60 million tons are produced worldwide every year. Polyethylene is obtained by the catalytic polymerization of ethylene in gas and liquid phase reactors. The gas phase processes are more advantageous, and use fluidized-bed reactors for production of polyethylene. Since they operate so close to the melting point of the polymer, agglomeration is an operational concern in all slurry and gas polymerization processes. Electrostatics and hot spot formation are the main factors that contribute to agglomeration in gas-phase processes. Electrostatic charges in gas phase polymerization fluidized bed reactors are known to influence the bed hydrodynamics, particle elutriation, bubble size, bubble shape etc. Accumulation of electrostatic charges in the fluidized-bed can lead to operational issues. In this work a first-principles electrostatic model is developed and coupled with a multi-fluid computational fluid dynamic (CFD) model to understand the effect of electrostatics on the dynamics of a fluidized-bed. The multi-fluid CFD model for gas-particle flow is based on the kinetic theory of granular flows closures. The electrostatic model is developed based on a fixed, size-dependent charge for each type of particle (catalyst, polymer, polymer fines) phase. The combined CFD model is first verified using simple test cases, validated with experiments and applied to a pilot-scale polymerization fluidized-bed reactor. The CFD model reproduced qualitative trends in particle segregation and entrainment due to electrostatic charges observed in experiments. For the scale up of fluidized bed reactor, filtered models are developed and implemented on pilot scale reactor.
Detection and differentiation of coxiella burnetii in biological fluids
Energy Technology Data Exchange (ETDEWEB)
Frazier, Marvin E. (Richland, WA); Mallavia, Louis P. (Moscow, ID); Samuel, James E. (Derwood, MD); Baca, Oswald G. (Albuquerque, NM)
1993-01-01
Methods for detecting the presence of Coxiella burnetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA with a DNA probe containing DNA sequences that specifically hybridize with C. burnetii DNA of strains associated with the capacity to cause acute or chronic disease.
Detection and differentiation of coxiella burnetii in biological fluids
Energy Technology Data Exchange (ETDEWEB)
Frazier, Marvin E. (Richland, WA); Mallavia, Louis P. (Moscow, ID); Samuel, James E. (Pullman, WA); Baca, Oswald G. (Albuquerque, NM)
1990-01-01
Methods for detecting the presence of Coxiella burenetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA (specifically rickettsial DNA) with a C. burnetii-specific labeled DNA probe. Radioisotope and biotin labels are preferred, allowing detection through autoradiography and colorimetric assays, respectively.
Detection and differentiation of coxiella burnetii in biological fluids
Energy Technology Data Exchange (ETDEWEB)
Frazier, Marvin E. (Richland, WA); Mallavia, Louis P. (Moscow, ID); Baca, Oswald G. (Albuquerque, NM); Samuel, James E. (Pullman, WA)
1989-01-01
Methods for detecting the presence of Coxiella burnetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA (specifically rickettsial DNA) with a C. burnetii-specific labeled DNA probe. Radioisotope and biotin labels are preferred, allowing detection through autoradiography and colorimetric assays, respectively.
Coupled problems in transient fluid and structural dynamics in nuclear engineering
International Nuclear Information System (INIS)
Krieg, R.
1978-01-01
Some important problems in coupled fluid-structural dynamics which occur in safety investigations of liquid metal fast breeder reactors (LMFBR). light water reactors and nuclear reprocessing plants are discussed and a classification of solution methods is introduced. A distinction is made between the step by step solution procedure, where available computer codes in fluid and structural dynamics are coupled, and advanced simultaneous solution methods, where the coupling is carried out at the level of the fundamental equations. Results presented include the transient deformation of a two-row pin bundle surrounded by an infinite fluid field, vapour explosions in a fluid container and containment distortions due to bubble collapse in the pressure suppression system of a boiling water reactor. A recently developed simultaneous solution method is presented in detail. Here the fluid dynamics (inviscid, incompressible fluid) is described by a singularity method which reduces the three-dimensional fluid dynamics problems to a two-dimensional formulation. In this way the three-dynamics fluid dynamics as well as the structural (shell) dynamics can be described essentially by common unknowns at the fluid-structural interface. The resulting equations for the coupled fluid-structural dynamics are analogous to to the equations of motion of the structural dynamics alone. (author)
Network Reconstruction of Dynamic Biological Systems
Asadi, Behrang
2013-01-01
Inference of network topology from experimental data is a central endeavor in biology, since knowledge of the underlying signaling mechanisms a requirement for understanding biological phenomena. As one of the most important tools in bioinformatics area, development of methods to reconstruct biological networks has attracted remarkable attention in the current decade. Integration of different data types can lead to remarkable improvements in our ability to identify the connectivity of differe...
Directory of Open Access Journals (Sweden)
Mariya A. Dikovskaya
2013-08-01
Full Text Available Objectives. To investigate the possible role of cystatin C in eye biological fluids locally and in serum and lactoferrin revealing anti-tumor activity in eye tumor development. Background. The increased number of eye tumors was registered recently not only in the countries with high insolation, but also in the northern countries including Russia (11 cases per million of population. Search for new biological markers is important for diagnosis and prognosis in eye tumors. Cystatin C, an endogenous inhibitor of cysteine proteases, plays an important protective role in several tumors. Lactoferrin was shown to express anti-tumor and antiviral activities. It was hypothesized that cystatin C and lactoferrin could serve as possible biomarkers in the diagnosis of malignant and benign eye tumors. Study design. A total of 54 patients with choroidal melanoma and benign eye tumors were examined (part of them undergoing surgical treatment. Serum, tear fluid and intraocular fluid samples obtained from the anterior chamber of eyes in patients with choroidal melanoma were studied. Methods. Cystatin C concentration in serum and eye biological fluids was measured by commercial ELISA kits for human (BioVendor, Czechia; lactoferrin concentration – by Lactoferrin-strip D 4106 ELISA test systems (Vector-BEST, Novosibirsk Region, Russia. Results. Cystatin C concentration in serum of healthy persons was significantly higher as compared to tear and intraocular fluids. In patients with choroidal melanoma, increased cystatin C concentration was similar in tear fluid of both the eyes. Lactoferrin level in tear fluid of healthy persons was significantly higher than its serum level. Significantly increased lactoferrin concentration in tear fluid was noted in patients with benign and malignant eye tumors. Conclusion. Increased level of cystatin C in tear fluid seems to be a possible diagnostic factor in the eye tumors studied. However, it does not allow us to differentiate
A dynamic optical measurement system for cryogenic fluids using laser interferometry
International Nuclear Information System (INIS)
Zhang, J H; Bao, S R; Zhang, R P; Qiu, L M
2015-01-01
Dynamic visualization is of great significance in the research of flow conditions and mass transfer process of cryogenic fluids. In this paper, two common ways to measure the concentration of cryogenic fluids are introduced and compared. To improve the real-time monitoring of cryogenic fluid, a non-contact dynamic optical measurement system using laser interferometry is designed, which is sensitive to subtle changes of fluid concentration. A precise and dynamic interference pattern can be obtained using this system. Two-dimensional concentration distribution of the fluid can be calculated from the interference pattern. Detailed calculation process is presented in the paper. (paper)
Stochastic modelling of dynamical systems in biology
Pellin, Danilo
2017-01-01
In this thesis two relevant biological problems will be addressed from a statistical modelling perspective. The first regards the study of hematopoiesis, a still not well understood biological process rarely observable in humans due to technical and ethical reasons. Hematopoiesis is responsible for
Fluid Dynamics of Carbon Dioxide Disposal into Saline Aquifers
Energy Technology Data Exchange (ETDEWEB)
Garcia, Julio Enrique [Univ. of California, Berkeley, CA (United States)
2003-01-01
Injection of carbon dioxide (CO_{2}) into saline aquifers has been proposed as a means to reduce greenhouse gas emissions (geological carbon sequestration). Large-scale injection of CO_{2} will induce a variety of coupled physical and chemical processes, including multiphase fluid flow, fluid pressurization and changes in effective stress, solute transport, and chemical reactions between fluids and formation minerals. This work addresses some of these issues with special emphasis given to the physics of fluid flow in brine formations. An investigation of the thermophysical properties of pure carbon dioxide, water and aqueous solutions of CO_{2} and NaCl has been conducted. As a result, accurate representations and models for predicting the overall thermophysical behavior of the system CO_{2}-H_{2}O-NaCl are proposed and incorporated into the numerical simulator TOUGH2/ECO2. The basic problem of CO_{2} injection into a radially symmetric brine aquifer is used to validate the results of TOUGH2/ECO2. The numerical simulator has been applied to more complex flow problem including the CO_{2} injection project at the Sleipner Vest Field in the Norwegian sector of the North Sea and the evaluation of fluid flow dynamics effects of CO_{2} injection into aquifers. Numerical simulation results show that the transport at Sleipner is dominated by buoyancy effects and that shale layers control vertical migration of CO_{2}. These results are in good qualitative agreement with time lapse surveys performed at the site. High-resolution numerical simulation experiments have been conducted to study the onset of instabilities (viscous fingering) during injection of CO_{2} into saline aquifers. The injection process can be classified as immiscible displacement of an aqueous phase by a less dense and less viscous gas phase. Under disposal conditions (supercritical CO_{2}) the viscosity of carbon
Sheppard, Kayleigh; Cassella, John P; Fieldhouse, Sarah; King, Roberto
2017-07-01
One of the most important and commonly encountered evidence types that can be recovered at crime scenes are biological fluids. Due to the ephemeral nature of biological fluids and the valuable DNA that they can contain, it is fundamental that these are documented extensively and recovered rapidly. Locating and identifying biological fluids can prove a challenging task but can aid in reconstructing a sequence of events. Alternate light sources (ALS) offer powerful non-invasive methods for locating and enhancing biological fluids utilising different wavelengths of light. Current methods for locating biological fluids using ALS's may be time consuming, as they often require close range searching of potentially large crime scenes. Subsequent documentation using digital cameras and alternate light sources can increase the investigation time and due to the cameras low dynamic range, photographs can appear under or over exposed. This study presents a technique, which allows the simultaneous detection and visualisation of semen and saliva utilising a SceneCam 360° camera (Spheron VR AG), which was adapted to integrate a blue Crime Lite XL (Foster+Freeman). This technique was investigated using different volumes of semen and saliva, on porous and non-porous substrates, and the ability to detect these at incremental distances from the substrate. Substrate type and colour had a significant effect on the detection of the biological fluid, with limited fluid detection on darker substrates. The unique real-time High Dynamic range (HDR) ability of the SceneCam significantly enhanced the detection of biological fluids where background fluorescence masked target fluorescence. These preliminary results are presented as a proof of concept for combining 360° photography using HDR and an ALS for the detection of biological stains, within a scene, in real time, whilst conveying spatial relationships of staining to other evidence. This technique presents the opportunity to
Computational Fluid Dynamic (CFD) Study of an Articulating Turbine Blade Cascade
2016-11-01
ARL-TR-7871 ● NOV 2016 US Army Research Laboratory Computational Fluid Dynamic (CFD) Study of an Articulating Turbine Blade...ARL-TR-7871 ● NOV 2016 US Army Research Laboratory Computational Fluid Dynamic (CFD) Study of an Articulating Turbine Blade Cascade by Luis...COVERED (From - To) 1 June–31 August 2016 4. TITLE AND SUBTITLE Computational Fluid Dynamic (CFD) Study of an Articulating Turbine Blade Cascade 5a
2016-04-01
ARL-TR-7660 ● APR 2016 US Army Research Laboratory Computational Fluid Dynamics (CFD) Simulations of a Finned Projectile with... Computational Fluid Dynamics (CFD) Simulations of a Finned Projectile with Microflaps for Flow Control by Jubaraj Sahu Weapons and Materials Research...TITLE AND SUBTITLE Computational Fluid Dynamics (CFD) Simulations of a Finned Projectile with Microflaps for Flow Control 5a. CONTRACT NUMBER 5b
Cannabinoid Markers in Biological Fluids and Tissues: Revealing Intake.
Huestis, Marilyn A; Smith, Michael L
2018-02-01
Understanding cannabis and synthetic cannabinoid intake history is vital for treating drug dependence, investigating cannabinoid effects, and providing information to healthcare personnel, medical examiners, and public health officials; this is particularly relevant today with cannabis medicalization and legalization. Required information includes identifying exposure, time of use, frequency of use, relapse, withdrawal, and predicting cannabinoid effects. Recent controlled cannabinoid administration studies enable the development of models and markers to better identify patterns of intake and exposure. Future challenges include developing behavioral markers of cannabis impairment, bringing to market breathalyzers for cannabinoid detection, and identifying markers of recent cannabis intake in diverse biological matrices. We posit that biological monitoring of cannabinoids and metabolites will improve the characterization of cannabis and synthetic cannabinoid intake history. Copyright © 2017 Elsevier Ltd. All rights reserved.
Computational Fluid Dynamics Demonstration of Rigid Bodies in Motion
Camarena, Ernesto; Vu, Bruce T.
2011-01-01
The Design Analysis Branch (NE-Ml) at the Kennedy Space Center has not had the ability to accurately couple Rigid Body Dynamics (RBD) and Computational Fluid Dynamics (CFD). OVERFLOW-D is a flow solver that has been developed by NASA to have the capability to analyze and simulate dynamic motions with up to six Degrees of Freedom (6-DOF). Two simulations were prepared over the course of the internship to demonstrate 6DOF motion of rigid bodies under aerodynamic loading. The geometries in the simulations were based on a conceptual Space Launch System (SLS). The first simulation that was prepared and computed was the motion of a Solid Rocket Booster (SRB) as it separates from its core stage. To reduce computational time during the development of the simulation, only half of the physical domain with respect to the symmetry plane was simulated. Then a full solution was prepared and computed. The second simulation was a model of the SLS as it departs from a launch pad under a 20 knot crosswind. This simulation was reduced to Two Dimensions (2D) to reduce both preparation and computation time. By allowing 2-DOF for translations and 1-DOF for rotation, the simulation predicted unrealistic rotation. The simulation was then constrained to only allow translations.
Coalescence dynamics of mobile and immobile fluid interfaces
Vakarelski, Ivan Uriev
2018-01-12
Coalescence dynamics between deformable bubbles and droplets can be dramatically affected by the mobility of the interfaces with fully tangentially mobile bubble-liquid or droplet-liquid interfaces expected to accelerate the coalescence by orders of magnitudes. However, there is a lack of systematic experimental investigations that quantify this effect. By using high speed camera imaging we examine the free rise and coalescence of small air-bubbles (100 to 1300 μm in diameter) with a liquid interface. A perfluorocarbon liquid, PP11 is used as a model liquid to investigate coalescence dynamics between fully-mobile and immobile deformable interfaces. The mobility of the bubble surface was determined by measuring the terminal rise velocity of small bubbles rising at Reynolds numbers, Re less than 0.1 and the mobility of free PP11 surface by measuring the deceleration kinetics of the small bubble toward the interface. Induction or film drainage times of a bubble at the mobile PP11-air surface were found to be more than two orders of magnitude shorter compared to the case of bubble and an immobile PP11-water interface. A theoretical model is used to illustrate the effect of hydrodynamics and interfacial mobility on the induction time or film drainage time. The results of this study are expected to stimulate the development of a comprehensive theoretical model for coalescence dynamics between two fully or partially mobile fluid interfaces.
Sharma, V K; Mamontov, E; Anunciado, D B; O'Neill, H; Urban, V
2015-03-26
The dynamics of phospholipids in unilamellar vesicles (ULVs) is of interest in biology, medical, and food sciences, since these molecules are widely used as biocompatible agents and a mimic of cell membrane systems. We have investigated the nanoscopic dynamics of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) phospholipid in ULVs as a function of temperature using elastic and quasielastic neutron scattering (QENS). The dependence of the signal on the scattering momentum transfer, which is a critical advantage of neutron scattering techniques, allows the detailed analysis of the lipid motions that cannot be carried out by other means. In agreement with a differential scanning calorimetry measurement, a sharp rise in the elastic scattering intensity below ca. 296 K indicates a phase transition from the high-temperature fluid phase to the low-temperature solid gel phase. The microscopic lipid dynamics exhibits qualitative differences between the solid gel phase (in a measurement at 280 K) and the fluid phase (in a measurement at a physiological temperature of 310 K). The analysis of the data demonstrates the presence of two types of distinct motions: the entire lipid molecule motion within a monolayer, also known as lateral diffusion, and the relatively faster internal motion of the DMPC molecule. The lateral diffusion of the entire lipid molecule is Fickian in character, whereas the internal lipid motions are of localized character, which is consistent with the structure of the vesicles. The lateral motion slows down by an order of magnitude in the solid gel phase, whereas for the internal motion not only the time scale but also the character of the motion changes upon the phase transition. In the solid gel phase, the lipids are more ordered and undergo uniaxial rotational motion. However, in the fluid phase, the hydrogen atoms of the lipid tails undergo confined translation diffusion rather than uniaxial rotational diffusion. The translational, but spatially
An Automated High Aspect Ratio Mesher for Computational Fluid Dynamics, Phase II
National Aeronautics and Space Administration — Computational fluid dynamics (CFD) simulations are routinely used while designing, analyzing, and optimizing air- and spacecraft. An important component of CFD...
National Research Council Canada - National Science Library
Nusca, Michael J; Chen, Chiung-Chu; McQuaid, Michael J
2007-01-01
.... Computational fluid dynamics is employed to model the chemically reacting flow within a system's combustion chamber, and computational chemistry is employed to characterize propellant physical and reactive properties...
National Research Council Canada - National Science Library
Weinacht, Paul
2003-01-01
... that are derived solely from computational fluid dynamics (CFD). As a demonstration of the capability, this report presents results for a family of axisymmetric projectiles in supersonic flight...
An Automated High Aspect Ratio Mesher for Computational Fluid Dynamics, Phase I
National Aeronautics and Space Administration — Computational fluid dynamics (CFD) simulations are routinely used while designing, analyzing, and optimizing air- and spacecraft. An important component of CFD...
Feedback dynamics and cell function: Why systems biology is called Systems Biology.
Wolkenhauer, Olaf; Mesarovic, Mihajlo
2005-05-01
A new paradigm, like Systems Biology, should challenge the way research has been conducted previously. This Opinion article aims to present Systems Biology, not as the application of engineering principles to biology but as a merger of systems- and control theory with molecular- and cell biology. In our view, the central dogma of Systems Biology is that it is system dynamics that gives rise to the functioning and function of cells. The concepts of feedback regulation and control of pathways and the coordination of cell function are emphasized as an important area of Systems Biology research. The hurdles and risks for this area are discussed from the perspective of dynamic pathway modelling. Most of all, the aim of this article is to promote mathematical modelling and simulation as a part of molecular- and cell biology. Systems Biology is a success if it is widely accepted that there is nothing more practical than a good theory.
Computational fluid dynamics (CFD) studies of a miniaturized dissolution system.
Frenning, G; Ahnfelt, E; Sjögren, E; Lennernäs, H
2017-04-15
Dissolution testing is an important tool that has applications ranging from fundamental studies of drug-release mechanisms to quality control of the final product. The rate of release of the drug from the delivery system is known to be affected by hydrodynamics. In this study we used computational fluid dynamics to simulate and investigate the hydrodynamics in a novel miniaturized dissolution method for parenteral formulations. The dissolution method is based on a rotating disc system and uses a rotating sample reservoir which is separated from the remaining dissolution medium by a nylon screen. Sample reservoirs of two sizes were investigated (SR6 and SR8) and the hydrodynamic studies were performed at rotation rates of 100, 200 and 400rpm. The overall fluid flow was similar for all investigated cases, with a lateral upward spiraling motion and central downward motion in the form of a vortex to and through the screen. The simulations indicated that the exchange of dissolution medium between the sample reservoir and the remaining release medium was rapid for typical screens, for which almost complete mixing would be expected to occur within less than one minute at 400rpm. The local hydrodynamic conditions in the sample reservoirs depended on their size; SR8 appeared to be relatively more affected than SR6 by the resistance to liquid flow resulting from the screen. Copyright © 2017 Elsevier B.V. All rights reserved.
Review of computational fluid dynamics applications in biotechnology processes.
Sharma, C; Malhotra, D; Rathore, A S
2011-01-01
Computational fluid dynamics (CFD) is well established as a tool of choice for solving problems that involve one or more of the following phenomena: flow of fluids, heat transfer,mass transfer, and chemical reaction. Unit operations that are commonly utilized in biotechnology processes are often complex and as such would greatly benefit from application of CFD. The thirst for deeper process and product understanding that has arisen out of initiatives such as quality by design provides further impetus toward usefulness of CFD for problems that may otherwise require extensive experimentation. Not surprisingly, there has been increasing interest in applying CFD toward a variety of applications in biotechnology processing in the last decade. In this article, we will review applications in the major unit operations involved with processing of biotechnology products. These include fermentation,centrifugation, chromatography, ultrafiltration, microfiltration, and freeze drying. We feel that the future applications of CFD in biotechnology processing will focus on establishing CFD as a tool of choice for providing process understanding that can be then used to guide more efficient and effective experimentation. This article puts special emphasis on the work done in the last 10 years. © 2011 American Institute of Chemical Engineers
Resistive fluid turbulence and tokamak edge plasma dynamics
International Nuclear Information System (INIS)
Thayer, D.R.; Diamond, P.H.; Ritz, C.P.
1988-01-01
Electrostatic and electromagnetic turbulence has been linked to particle and heat transport in tokamaks. Here we report on several related theoretical and experimental investigations of edge plasma dynamics. The theory of thermally-driven convective cell edge turbulence has been developed to treat the coupling of the radiative-condensation instability to the resistivity-gradient expansion free energy. This model of edge turbulence has led to theoretical understanding of several anomalies in electrostatic edge turbulence found from experiment: that fluctuation levels and transport coefficients are larger than naively expected, that potential fluctuations are significantly larger than the density. Impurity gas-puffing experiments on the TEXT tokamak have been performed to test this theory, and have indicated favorable results. Resistive fluid turbulence models have also been explored and applied in the hope of understanding the extensive edge magnetic fluctuation studies. We discuss models of electromagnetic microtearing turbulence, resistive-pressure-gradient-driven turbulence, and ion temperature gradient driven turbulence. In particular we study the role of resistive fluid turbulence with separatrix effects in the L /yield/ H mode transition. 36 refs., 2 figs
Dynamic dielectric response of electrorheological fluids in drag flow.
Horváth, B; Szalai, I
2015-10-01
We have determined the response time of dilute electrorheological fluids (ER) in drag flow from the dynamic dielectric response. On the basis of a kinetic rate equation a new formula was derived to approximate the experimental time-dependent dielectric permittivity during the temporal evolution of the microstructure. The dielectric response time was compared to the standard rheological response time extracted from the time-dependent shear stress, and a good agreement was obtained. We found that the dielectric method is more sensitive to detect any transient during the chain formation process. The experimental saturation value of the dielectric permittivity corresponding to the equilibrium microstructure was estimated on the basis of formulas derived from the Clausius-Mossotti equation.
Using computational fluid dynamics to characterize and improve bioreactor performance.
Kelly, William J
2008-04-01
CFD (computational fluid dynamics) has been used to model upstream bioprocessing steps such as fermentation and homogenization. The focus of these studies has oftentimes been to characterize single-phase (liquid) flow and hydrodynamic shear. In the actual bioprocessing operations, however, there are at least two phases (cells and liquid) present. In the bioreactor, the gas bubbles constitute a third phase. More recent CFD models have considered the momentum and mass transfer that occurs between the phases. This review summarizes studies from the biochemical and biomedical literature relating to the use of CFD to model the performance of a variety of bioreactor types. Particular emphasis will be placed on describing current methods for handling multi-phase flow involving animal cells and/or gas bubbles.
Characterizing the fluid dynamics of the inverted frustoconical shaking bioreactor.
Zhu, Likuan; Zhang, Xueting; Cheng, Kai; Lv, Zhonghua; Zhang, Lei; Meng, Qingyong; Yuan, Shujie; Song, Boyan; Wang, Zhenlong
2018-01-05
The authors conducted a three-dimensional computational fluid dynamics (CFD) simulation to calculate the flow field in the inverted frustoconical shaking bioreactor with 5 L working volume (IFSB-5L). The CFD models were established for the IFSB-5L at different operating conditions (different shaking speeds and filling volumes) and validated by comparison of the liquid height distribution in the agitated IFSB-5L. The "out of phase" operating conditions were characterized by analyzing the flow field in the IFSB-5L at different filling volumes and shaking speeds. The values of volumetric power consumption (P/V L ) and volumetric mass transfer coefficient (k L a) were determined from simulated and experimental results, respectively. Finally, the operating condition effect on P/V L and k L a was investigated. © 2018 American Institute of Chemical Engineers Biotechnol. Prog., 2018. © 2018 American Institute of Chemical Engineers.
Computational Fluid Dynamics Analysis of an Evaporative Cooling System
Directory of Open Access Journals (Sweden)
Kapilan N.
2016-11-01
Full Text Available The use of chlorofluorocarbon based refrigerants in the air-conditioning system increases the global warming and causes the climate change. The climate change is expected to present a number of challenges for the built environment and an evaporative cooling system is one of the simplest and environmentally friendly cooling system. The evaporative cooling system is most widely used in summer and in rural and urban areas of India for human comfort. In evaporative cooling system, the addition of water into air reduces the temperature of the air as the energy needed to evaporate the water is taken from the air. Computational fluid dynamics is a numerical analysis and was used to analyse the evaporative cooling system. The CFD results are matches with the experimental results.
Computational methods of the Advanced Fluid Dynamics Model
International Nuclear Information System (INIS)
Bohl, W.R.; Wilhelm, D.; Parker, F.R.
1987-01-01
To more accurately treat severe accidents in fast reactors, a program has been set up to investigate new computational models and approaches. The product of this effort is a computer code, the Advanced Fluid Dynamics Model (AFDM). This paper describes some of the basic features of the numerical algorithm used in AFDM. Aspects receiving particular emphasis are the fractional-step method of time integration, the semi-implicit pressure iteration, the virtual mass inertial terms, the use of three velocity fields, higher order differencing, convection of interfacial area with source and sink terms, multicomponent diffusion processes in heat and mass transfer, the SESAME equation of state, and vectorized programming. A calculated comparison with an isothermal tetralin/ammonia experiment is performed. We conclude that significant improvements are possible in reliably calculating the progression of severe accidents with further development
Simulating Smoke Filling in Big Halls by Computational Fluid Dynamics
Directory of Open Access Journals (Sweden)
W. K. Chow
2011-01-01
Full Text Available Many tall halls of big space volume were built and, to be built in many construction projects in the Far East, particularly Mainland China, Hong Kong, and Taiwan. Smoke is identified to be the key hazard to handle. Consequently, smoke exhaust systems are specified in the fire code in those areas. An update on applying Computational Fluid Dynamics (CFD in smoke exhaust design will be presented in this paper. Key points to note in CFD simulations on smoke filling due to a fire in a big hall will be discussed. Mathematical aspects concerning of discretization of partial differential equations and algorithms for solving the velocity-pressure linked equations are briefly outlined. Results predicted by CFD with different free boundary conditions are compared with those on room fire tests. Standards on grid size, relaxation factors, convergence criteria, and false diffusion should be set up for numerical experiments with CFD.
Modeling centrifugal cell washers using computational fluid dynamics.
Kellet, Beth E; Han, Binbing; Dandy, David S; Wickramasinghe, S Ranil
2004-11-01
Reinfusion of shed blood during surgery could avoid the need for blood transfusions. Prior to reinfusion of the red blood cells, the shed blood must be washed in order to remove leukocytes, platelets, and other contaminants. Further, the hematocrit of the washed blood must be increased. The feasibility of using computational fluid dynamics (CFD) to guide the design of better centrifuges for processing shed blood is explored here. The velocity field within a centrifuge bowl and the rate of protein removal from the shed blood has been studied. The results obtained indicate that CFD could help screen preliminary centrifuge bowl designs, thus reducing the number of initial experimental tests required when developing new centrifuge bowls. Although the focus of this work is on washing shed blood, the methods developed here are applicable to the design of centrifuge bowls for other blood-processing applications.
On Computational Fluid Dynamics Tools in Architectural Design
DEFF Research Database (Denmark)
Kirkegaard, Poul Henning; Hougaard, Mads; Stærdahl, Jesper Winther
engineering computational fluid dynamics (CFD) simulation program ANSYS CFX and a CFD based representative program RealFlow are investigated. These two programs represent two types of CFD based tools available for use during phases of an architectural design process. However, as outlined in two case studies...... the durability of the two program types for simulation of flow is strongly depended of the purpose. One case presents results obtained with the programs with respect to the accuracy and physical behaviour of the flow. Another case deals with wind flow around a complex building design, the roof of the new Utzon...... Centre in Aalborg, Denmark. The obtained results show that detailed and accurate flow predictions can be obtained using a simulation tool like ANSYS CFX. On the other hand RealFlow provides satisfactory flow results for evaluation of a proposed building shape in an early phase of a design process...
Uncertainty quantification in computational fluid dynamics and aircraft engines
Montomoli, Francesco; D'Ammaro, Antonio; Massini, Michela; Salvadori, Simone
2015-01-01
This book introduces novel design techniques developed to increase the safety of aircraft engines. The authors demonstrate how the application of uncertainty methods can overcome problems in the accurate prediction of engine lift, caused by manufacturing error. This in turn ameliorates the difficulty of achieving required safety margins imposed by limits in current design and manufacturing methods. This text shows that even state-of-the-art computational fluid dynamics (CFD) are not able to predict the same performance measured in experiments; CFD methods assume idealised geometries but ideal geometries do not exist, cannot be manufactured and their performance differs from real-world ones. By applying geometrical variations of a few microns, the agreement with experiments improves dramatically, but unfortunately the manufacturing errors in engines or in experiments are unknown. In order to overcome this limitation, uncertainty quantification considers the probability density functions of manufacturing errors...
Dynamics of self-assembled chaining in magnetorheological fluids.
Climent, Eric; Maxey, Martin R; Karniadakis, George Em
2004-01-20
The aggregation dynamics of paramagnetic spherical particles embedded in a viscous fluid is investigated via numerical simulations using a fully coupled three-dimensional model. Particles experience simultaneously Brownian motion, dipolar magnetic attraction, and multibody hydrodynamic interactions. When the dipole strength characterizing the ratio of magnetic attraction to random diffusion exceeds a critical value, particles join together forming supraparticle structures. As time evolves, particle/chain and chain/ chain interactions lead to a continuous increase of the cluster size. The mean length of particle chains has a power-law dependence with respect to time, as predicted by the theory of diffusion-limited aggregation. Both the exponent and the characteristic time scale agree very well with the experimental results of Promislow et al.
Helicopter fuselage drag - combined computational fluid dynamics and experimental studies
Batrakov, A.; Kusyumov, A.; Mikhailov, S.; Pakhov, V.; Sungatullin, A.; Valeev, M.; Zherekhov, V.; Barakos, G.
2015-06-01
In this paper, wind tunnel experiments are combined with Computational Fluid Dynamics (CFD) aiming to analyze the aerodynamics of realistic fuselage configurations. A development model of the ANSAT aircraft and an early model of the AKTAI light helicopter were employed. Both models were tested at the subsonic wind tunnel of KNRTU-KAI for a range of Reynolds numbers and pitch and yaw angles. The force balance measurements were complemented by particle image velocimetry (PIV) investigations for the cases where the experimental force measurements showed substantial unsteadiness. The CFD results were found to be in fair agreement with the test data and revealed some flow separation at the rear of the fuselages. Once confidence on the CFD method was established, further modifications were introduced to the ANSAT-like fuselage model to demonstrate drag reduction via small shape changes.
Mapping flow distortion on oceanographic platforms using computational fluid dynamics
Directory of Open Access Journals (Sweden)
N. O'Sullivan
2013-10-01
Full Text Available Wind speed measurements over the ocean on ships or buoys are affected by flow distortion from the platform and by the anemometer itself. This can lead to errors in direct measurements and the derived parametrisations. Here we computational fluid dynamics (CFD to simulate the errors in wind speed measurements caused by flow distortion on the RV Celtic Explorer. Numerical measurements were obtained from the finite-volume CFD code OpenFOAM, which was used to simulate the velocity fields. This was done over a range of orientations in the test domain from −60 to +60° in increments of 10°. The simulation was also set up for a range of velocities, ranging from 5 to 25 m s−1 in increments of 0.5 m s−1. The numerical analysis showed close agreement to experimental measurements.
Study of blast wave overpressures using the computational fluid dynamics
Directory of Open Access Journals (Sweden)
M. L. COSTA NETO
Full Text Available ABSTRACT The threats of bomb attacks by criminal organizations and accidental events involving chemical explosives are a danger to the people and buildings. Due the severity of these issues and the need of data required for a safety design, more research is required about explosions and shock waves. This paper presents an assessment of blast wave overpressures using a computational fluid dynamics software. Analyses of phenomena as reflection of shock waves and channeling effects were done and a comparison between numerical results and analytical predictions has been executed, based on the simulation on several models. The results suggest that the common analytical predictions aren’t accurate enough for an overpressure analysis in small stand-off distances and that poorly designed buildings may increase the shock wave overpressures due multiple blast wave reflections, increasing the destructive potential of the explosions.
The characterization of exosomes from biological fluids of patients with different types of cancer
Yunusova, N. V.; Tamkovich, S. N.; Stakheeva, M. N.; Grigor'eva, A. A.; Somov, A. K.; Tugutova, E. A.; Kolomiets, L. A.; Molchanov, S. V.; Afanas'ev, S. G.; Kakurina, G. V.; Choinzonov, E. L.; Kondakova, I. V.
2017-09-01
Exosomes are extracellular membrane structures involved in many physiological and pathological processes including cancerogenesis and metastasis. The purpose of the study was to isolate, identify and analyze the total content of exosomes in biological fluids. The exosomes from the plasma and ascites samples of the patients with ovarian cancer, from the blood plasma of the patients with colorectal and head and neck squamous cell cancer as well as from the blood plasma of healthy donors were characterized using transmission electron microscopy and flow cytometry. The subpopulations of the exosomes in the biological fluids of the patients with different types of cancer were similar, but the protein concentrations of exosomes were different. In this paper we present the methodological approaches allowing us to obtain high quality exosome preparations from biological fluids.
Wu, Binxin
2010-12-01
In this paper, 12 turbulence models for single-phase non-newtonian fluid flow in a pipe are evaluated by comparing the frictional pressure drops obtained from computational fluid dynamics (CFD) with those from three friction factor correlations. The turbulence models studied are (1) three high-Reynolds-number k-ε models, (2) six low-Reynolds-number k-ε models, (3) two k-ω models, and (4) the Reynolds stress model. The simulation results indicate that the Chang-Hsieh-Chen version of the low-Reynolds-number k-ε model performs better than the other models in predicting the frictional pressure drops while the standard k-ω model has an acceptable accuracy and a low computing cost. In the model applications, CFD simulation of mixing in a full-scale anaerobic digester with pumped circulation is performed to propose an improvement in the effective mixing standards recommended by the U.S. EPA based on the effect of rheology on the flow fields. Characterization of the velocity gradient is conducted to quantify the growth or breakage of an assumed floc size. Placement of two discharge nozzles in the digester is analyzed to show that spacing two nozzles 180° apart with each one discharging at an angle of 45° off the wall is the most efficient. Moreover, the similarity rules of geometry and mixing energy are checked for scaling up the digester.
A fully dynamic magneto-rheological fluid damper model
Jiang, Z.; Christenson, R. E.
2012-06-01
Control devices can be used to dissipate the energy of a civil structure subjected to dynamic loading, thus reducing structural damage and preventing failure. Semiactive control devices have received significant attention in recent years. The magneto-rheological (MR) fluid damper is a promising type of semiactive device for civil structures due to its mechanical simplicity, inherent stability, high dynamic range, large temperature operating range, robust performance, and low power requirements. The MR damper is intrinsically nonlinear and rate-dependent, both as a function of the displacement across the MR damper and the command current being supplied to the MR damper. As such, to develop control algorithms that take maximum advantage of the unique features of the MR damper, accurate models must be developed to describe its behavior for both displacement and current. In this paper, a new MR damper model that includes a model of the pulse-width modulated (PWM) power amplifier providing current to the damper, a proposed model of the time varying inductance of the large-scale 200 kN MR dampers coils and surrounding MR fluid—a dynamic behavior that is not typically modeled—and a hyperbolic tangent model of the controllable force behavior of the MR damper is presented. Validation experimental tests are conducted with two 200 kN large-scale MR dampers located at the Smart Structures Technology Laboratory (SSTL) at the University of Illinois at Urbana-Champaign and the Lehigh University Network for Earthquake Engineering Simulation (NEES) facility. Comparison with experimental test results for both prescribed motion and current and real-time hybrid simulation of semiactive control of the MR damper shows that the proposed MR damper model can accurately predict the fully dynamic behavior of the large-scale 200 kN MR damper.
Population dynamics and biology of an invasive population of ...
African Journals Online (AJOL)
Population dynamics and biology of an invasive population of mosquitofish Gambusia affinis in a temperate estuarine lake system. Hans Sloterdijk, Nicola C. James, M Kyle S. Smith, Werner Ekau, Olaf L.F. Weyl ...
Non-Ideal Compressible Fluid Dynamics: A Challenge for Theory
Kluwick, A.
2017-03-01
The possibility that compression as well as rarefaction shocks may form in single phase vapours was envisaged first by Bethe (1942). However calculations based on the Van der Waals equation of state indicated that the latter type of shock is possible only if the specific heat at constant volume cv divided by the universal gas constant R is larger than about 17.5 which he considered too large to be satisfied by real fluids. This conclusion was contested by Thompson (1971) who showed that the type of shock capable of forming in arbitrary fluids is determined by the sign of the thermodynamic quantity to which he referred to as fundamental derivative of gas dynamics. Here v, p, s and c denote the specific volume, the pressure, the entropy and the speed of sound. Thompson and co-workers also showed that the required condition for the existence of rarefaction shocks, that Γ may take on negative values, is indeed satisfied for a number of hydrocarbon and fluorocarbon vapours. This finding spawned a burst of theoretical studies elaborating on the unusual and often counterintuitive behaviour of shocks with rarefaction shocks present. These produced both results of theoretical character but also results suggesting the practical importance of Non-Ideal Compressible Fluid Dynamics in general. The present paper addresses some of the challenges encountered in connection with the theoretical treatment of the associated flow behaviour. Weakly nonlinear acoustic waves of finite amplitude serve as a starting point. Here mixed rather than strictly positive nonlinearity generates a wealth of phenomena not possible in perfect gases. Examples of steady flows where these non-classical effects play a decisive role (and which may be useful also for future experimental work) are quasi one-dimensional nozzle flows and transonic two-dimensional flows past corners. The study of viscous effects concentrates on laminar flows of boundary layer type. Here non-classical phenomena are caused by the
Method for detection of a suspect viral deoxyribonucleic acid in an acellular biological fluid
International Nuclear Information System (INIS)
Berninger, M.S.
1982-01-01
A method for evaluating an acellular biological fluid for the presence of a suspect viral DNA, such as DNA of the Hepatitis-B virus, is described. The acellular biological fluid is treated to immobilize in denatured form the DNAs including the suspect viral DNA on a solid substrate. This substrate is contacted with a solution including radioisotopically-labelled suspect viral denatured DNA to renature the immobilized suspect viral native DNA. The solid substrate is then evaluated for radioisotopically-labelled suspect viral renatured DNA. (author)
Separation methods for captopril in pharmaceuticals and biological fluids.
Mansour, Fotouh R; Danielson, Neil D
2012-06-01
Captopril (CAP) is an orally active angiotensin-converting enzyme (ACE) inhibitor and has been widely used for management of hypertension and congestive heart failure. CAP lacks an aromatic chromophore required for facile direct UV detection and also has two chiral centers. These factors can render the determination of CAP in complex matrices challenging. This review covers more than 20 years of analytical research on this drug, focusing mainly on pharmaceutical and biological applications. The primary separation techniques discussed are gas chromatography, liquid chromatography, and capillary electrophoresis. The structures of the CAP derivatizing agents as well as a table summarizing various HPLC methods are provided. A discussion of key recent chromatographic and electrophoretic methods for other ACE inhibitors is also present. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Mullett, Wayne M
2007-03-10
The analysis of drugs in various biological fluids is an important criterion for the determination of the physiological performance of a drug. After sampling of the biological fluid, the next step in the analytical process is sample preparation. The complexity of biological fluids adds to the challenge of direct determination of the drug by chromatographic analysis, therefore demanding a sample preparation step that is often time-consuming, tedious, and frequently overlooked. However, direct on-line injection methods offer the advantage of reducing sample preparation steps and enabling effective pre-concentration and clean-up of biological fluids. These procedures can be automated and therefore reduce the requirements for handling potentially infectious biomaterial, improve reproducibility, and minimize sample manipulations and potential contamination. The objective of this review is to present an overview of the existing literature with emphasis on advances in automated sample preparation methods for liquid-chromatographic methods. More specifically, this review concentrates on the use of direct injection techniques, such as restricted-access materials, turbulent-flow chromatography and other automated on-line solid-phase extraction (SPE) procedures. It also includes short overviews of emerging automated extraction-phase technologies, such as molecularly imprinted polymers, in-tube solid-phase micro-extraction, and micro-extraction in a packed syringe for a more selective extraction of analytes from complex samples, providing further improvements in the analysis of biological materials. Lastly, the outlook for these methods and potential new applications for these technologies are briefly discussed.
Nonlinear fluid dynamics of nanoscale hydration water layer
Jhe, Wonho; Kim, Bongsu; Kim, Qhwan; An, Sangmin
In nature, the hydration water layer (HWL) ubiquitously exists in ambient conditions or aqueous solutions, where water molecules are tightly bound to ions or hydrophilic surfaces. It plays an important role in various mechanisms such as biological processes, abiotic materials, colloidal interaction, and friction. The HWL, for example, can be easily formed between biomaterials since most biomaterials are covered by hydrophilic molecules such as lipid bilayers, and this HWL is expected to be significant to biological and physiological functions. Here (1) we present the general stress tensor of the hydration water layer. The hydration stress tensor provided the platform form for holistic understanding of the dynamic behaviors of the confined HWL including tapping and shear dynamics which are until now individually studied. And, (2) through fast shear velocity ( 1mm/s) experiments, the elastic turbulence caused by elastic property of the HWL is indirectly observed. Our results may contribute to a deeper study of systems where the HWL plays an important role such as biomolecules, colloidal particles, and the MEMS. This work was supported by the National Research Foundation of Korea(NRF) Grant funded by the Korea government(MSIP) (2016R1A3B1908660).
Modeling the Effect of Fluid-Structure Interaction on the Impact Dynamics of Pressurized Tank Cars
2009-11-13
This paper presents a computational framework that : analyzes the effect of fluid-structure interaction (FSI) on the : impact dynamics of pressurized commodity tank cars using the : nonlinear dynamic finite element code ABAQUS/Explicit. : There exist...
APS presents prizes in fluid dynamics and plasma physics
International Nuclear Information System (INIS)
Anon.
1992-01-01
This article reviews the presentation of the American Physical Society awards in fluid dynamics and plasma physics. The recipient of the plasma physics James Clerk Maxwell Prize was John M. Green for contributions to the theory of magnetohydrodynamics equilibria and ideal and resistive instabilities, for discovering the inverse scattering transform leading to soliton solutions of many nonlinear partial differential equations and for inventing the residue method of determining the transition to global chaos. The excellence in Plasma Physics Research Award was presented to Nathaniel A. Fisch for theoretical investigations of noninductive current generation in toroidally confined plasma. Wim Pieter Leemans received the Simon Ramo Award for experimental and simulational contributions to laser-plasma physics. William R. Sears was given the 1992 Fuid Dynamics Prize for contributions to the study of steady and unsteady aerodynamics, aeroacoustics, magnetoaerodynamics,and wind tunnel design. William C. Reynolds received the Otto Laporte Award for experimental, theoretical, and computational work in turbulence modeling and control and leadership in direct numerical simulation and large eddy simulation
Application of computational fluid dynamics in tissue engineering.
Patrachari, Anirudh R; Podichetty, Jagdeep T; Madihally, Sundararajan V
2012-08-01
The process of tissue regeneration consists of a set of complex phenomena such as hydrodynamics, nutrient transfer, cell growth, and matrix deposition. Traditional cell culture and bioreactor design procedure follow trial-and-error analyses to understand the effects of varying physical, chemical, and mechanical parameters that govern the process of tissue regeneration. This trend has been changing as computational fluid dynamics (CFD) analysis can now be used to understand the effects of flow, cell proliferation, and consumption kinetics on the dynamics involved with in vitro tissue regeneration. Furthermore, CFD analyses enable understanding the influence of nutrient transport on cell growth and the effect of cell proliferation as the tissue regenerates. This is especially advantageous in improving and optimizing the design of bioreactors and tissue culture. Influence of parameters such as velocity, oxygen tension, stress, and strain on tissue growth can be effectively studied throughout the bioreactor using CFD as it becomes impractical and cumbersome to install probes at several locations in the bioreactor. Hence, CFD offers several advantages for the advancement of tissue engineering. Copyright © 2012 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
The fluid dynamics of deep-sea mining
Peacock, Thomas; Rzeznik, Andrew
2017-11-01
With vast mineral deposits on the ocean floor, deep-sea nodule mining operations are expected to commence in the next decade. Among several fundamental fluid dynamics problems, this could involve plans for dewatering plumes to be released into the water column by surface processing vessels. To study this scenario, we consider the effects of non-uniform, realistic stratifications on forced compressible plumes with finite initial size. The classical plume model is developed to take into account the influence of thermal conduction through the dewatering pipe and also compressibility effects, for which a dimensionless number is introduced to determine their importance compared to the background stratification. Among other things, our results show that small-scale features of a realistic stratification can have a large effect on plume dynamics compared to smoothed profiles and that for any given set of environmental parameters there is a discharge flow rate that minimizes the plume vertical extent. Our findings are put in the context of nodule mining plumes for which the rapid and efficient re-sedimentation of waste material has important environmental consequences.
Three-dimensional dynamics of supported pipes conveying fluid
Wang, L.; Jiang, T. L.; Dai, H. L.
2017-12-01
This paper deals with the three-dimensional dynamics and postbuckling behavior of flexible supported pipes conveying fluid, considering flow velocities lower and higher than the critical value at which the buckling instability occurs. In the case of low flow velocity, the pipe is stable with a straight equilibrium position and the dynamics of the system can be examined using linear theory. When the flow velocity is beyond the critical value, any motions of the pipe could be around the postbuckling configuration (non-zero equilibrium position) rather than the straight equilibrium position, so nonlinear theory is required. The nonlinear equations of perturbed motions around the postbuckling configuration are derived and solved with the aid of Galerkin discretization. It is found, for a given flow velocity, that the first-mode frequency for in-plane motions is quite different from that for out-of-plane motions. However, the second- or third-mode frequencies for in-plane motions are approximately equal to their counterparts for out-of-plane motions, keeping almost constant values with increasing flow velocity. Moreover, the orientation angle of the postbuckling configuration plane for a buckled pipe can be significantly affected by initial conditions, displaying new features which have not been observed in the same pipe system factitiously supposed to deform in a single plane.
Turbulent Dynamics of Partially-Ionized Fluids in 2D
Benavides, S.; Flierl, G.
2017-12-01
Ionization occurs in the upper atmospheres of Hot Jupiters, as well asthe interiors of Gas Giants, leading to Magnetohydrodynamic (MHD) effectswhich can significantly alter the flow. The interactions of these MHDregions with the non-ionized atmosphere will occur in transitionregions where only a fraction of the fluid is ionized. We areexploring the dynamics of Partially-Ionized MHD (PIMHD) using a twofluid model - one neutral and one ionized and subject to MHD -coupled by a collision, or Joule heating, term proportional to thedifference in velocities. By varying both the ionization fraction aswell as the collision frequency (coupling), we examine the parameterspace of 2D PIMHD turbulence in hopes of better understanding itscharacteristics in certain, possibly realistic, regimes. We payparticular attention to the Joule heating term and its role indissipation and energy exchange between the two species. Thisknowledge will serve as the basis to further studies in which we lookat, in a more realistic setting, the PIMHD dynamics in Gas Giant orHot Jupiter atmospheres.
Fluid dynamics of competitive swimming: An experimental study
Wei, T.; Voorhees, A.; Mark, R.; Mittal, R.
2004-11-01
The world of competitive swimming is dynamic. Swimmers today are bigger, stronger and faster than they ever have been. The training regimen of an elite athlete includes not only endless practice of his or her skills, but also a carefully planned diet, strength and endurance training, and hours of mental preparation. Within this framework, researchers from Rutgers and George Washington Universities have teamed with USA Swimming to develop advanced, fluid dynamics based training and analysis tools for current and future Olympic swimmers. The focus of this presentation will be on the objectives, methodologies and early outcomes of DPIV measurements of flow around swimmers. Testing was conducted at the Olympic training center in Colorado Springs and focussed specifically on the dolphin kick, an undulating motion swimmers use at the beginning of a race and after pushing off from the wall during a turn. Movies of flow measurements around swimmers, including Beth Botsford, the 1996 Olympic Gold Medalist in the 100 m backstroke, will be presented.
Unsteady computational fluid dynamics in front crawl swimming.
Samson, Mathias; Bernard, Anthony; Monnet, Tony; Lacouture, Patrick; David, Laurent
2017-05-01
The development of codes and power calculations currently allows the simulation of increasingly complex flows, especially in the turbulent regime. Swimming research should benefit from these technological advances to try to better understand the dynamic mechanisms involved in swimming. An unsteady Computational Fluid Dynamics (CFD) study is conducted in crawl, in order to analyse the propulsive forces generated by the hand and forearm. The k-ω SST turbulence model and an overset grid method have been used. The main objectives are to analyse the evolution of the hand-forearm propulsive forces and to explain this relative to the arm kinematics parameters. In order to validate our simulation model, the calculated forces and pressures were compared with several other experimental and numerical studies. A good agreement is found between our results and those of other studies. The hand is the segment that generates the most propulsive forces during the aquatic stroke. As the pressure component is the main source of force, the orientation of the hand-forearm in the absolute coordinate system is an important kinematic parameter in the swimming performance. The propulsive forces are biggest when the angles of attack are high. CFD appears as a very valuable tool to better analyze the mechanisms of swimming performance and offers some promising developments, especially for optimizing the performance from a parametric study.
Dynamics of tubes in fluid with tube-baffle interaction
International Nuclear Information System (INIS)
Chen, S.S.; Jendrzejczyk, J.A.; Wambsganss, M.W.
1983-09-01
Three series of tests are performed to evaluate the effects of tube to tube-support-plate (TSP) clearance on tube dynamic characteristics and instability phenomena for tube arrays in crossflow. Test results show that, for relatively large clearances, tubes may possess TSP-inactive modes in which the tubes rattle inside some of the tube-support-plate holes, and that the natural frequencies of TSP-inactive modes are lower than those of TSP-active modes, in which the support plates provide knife-edge type support. Tube response characteristics associated with TSP-inactive modes are sensitive to tube-to-TSP clearance, TSP thickness, excitation amplitude, tube alignment, and the fluid inside the clearance. In addition, tube response is intrinsically nonlinear, with the dominance of TSP-inactive or TSP-active modes depending on the magnitudes of different system parameters. In general, such a system is difficult to model; only a full-scale test can provide all the necessary characteristics. A tube array supported by TSPs with relatively large clearances may be subjected to dynamic instability in some of the TSP-inactive modes; tube response characteristics and impact forces on TSPs for a tube row are studied in detail in this report. Tube displacements associated with the instability of a TSP-inactive mode are small; however, impacts of the tube against TSPs may result in significant damage in a relatively short time. 52 figures
A review on rising bubble dynamics in viscosity-stratified fluids
Indian Academy of Sciences (India)
Kirti Chandra Sahu
Systems with a bubble rising in a fluid, which has a variation of viscosity in space and time can be found in various natural phenomena and ... situations, due to the inherent presence of temperature variation and/or concentration gradient ... high contrasts in fluid properties, dynamically changing interface between the fluids, ...
On the fluid dynamics of a laboratory scale single-use stirred bioreactor
Odeleye, A.O.O.; Marsh, D.T.J.; Osborne, M.D.; Lye, G.J.; Micheletti, M.
2014-01-01
The commercial success of mammalian cell-derived recombinant proteins has fostered an increase in demand for novel single-use bioreactor (SUB) systems that facilitate greater productivity, increased flexibility and reduced costs (Zhang et al., 2010). These systems exhibit fluid flow regimes unlike those encountered in traditional glass/stainless steel bioreactors because of the way in which they are designed. With such disparate hydrodynamic environments between SUBs currently on the market, traditional scale-up approaches applied to stirred tanks should be revised. One such SUB is the Mobius® 3 L CellReady, which consists of an upward-pumping marine scoping impeller. This work represents the first experimental study of the flow within the CellReady using a Particle Image Velocimetry (PIV) approach, combined with a biological study into the impact of these fluid dynamic characteristics on cell culture performance. The PIV study was conducted within the actual vessel, rather than using a purpose-built mimic. PIV measurements conveyed a degree of fluid compartmentalisation resulting from the up-pumping impeller. Both impeller tip speed and fluid working volume had an impact upon the fluid velocities and spatial distribution of turbulence within the vessel. Cell cultures were conducted using the GS-CHO cell-line (Lonza) producing an IgG4 antibody. Disparity in cellular growth and viability throughout the range of operating conditions used (80–350 rpm and 1–2.4 L working volume) was not substantial, although a significant reduction in recombinant protein productivity was found at 350 rpm and 1 L working volume (corresponding to the highest Reynolds number tested in this work). The study shows promise in the use of PIV to improve understanding of the hydrodynamic environment within individual SUBs and allows identification of the critical hydrodynamic parameters under the different flow regimes for compatibility and scalability across the range of bioreactor
Modelling biological pathway dynamics with Timed Automata
Schivo, Stefano; Scholma, Jetse; Urquidi Camacho, R.A.; Wanders, B.; van der Vet, P.E.; Karperien, Hermanus Bernardus Johannes; Langerak, Romanus; van de Pol, Jan Cornelis; Post, Janine Nicole
2012-01-01
When analysing complex interaction networks occurring in biological cells, a biologist needs computational support in order to understand the effects of signalling molecules (e.g. growth factors, drugs). ANIMO (Analysis of Networks with Interactive MOdelling) is a tool that allows the user to create
Energy Technology Data Exchange (ETDEWEB)
Bowers, Geoffrey [Alfred Univ., NY (United States)
2017-04-05
United States Department of Energy grant DE-FG02-10ER16128, “Computational and Spectroscopic Investigations of the Molecular Scale Structure and Dynamics of Geologically Important Fluids and Mineral-Fluid Interfaces” (Geoffrey M. Bowers, P.I.) focused on developing a molecular-scale understanding of processes that occur in fluids and at solid-fluid interfaces using the combination of spectroscopic, microscopic, and diffraction studies with molecular dynamics computer modeling. The work is intimately tied to the twin proposal at Michigan State University (DOE DE-FG02-08ER15929; same title: R. James Kirkpatrick, P.I. and A. Ozgur Yazaydin, co-P.I.).
Thermophysical properties of fluids: dynamic viscosity and thermal conductivity
Latini, G.
2017-11-01
Thermophysical properties of fluids strongly depend upon atomic and molecular structure, complex systems governed by physics laws providing the time evolution. Theoretically the knowledge of the initial position and velocity of each atom, of the interaction forces and of the boundary conditions, leads to the solution; actually this approach contains too many variables and it is generally impossible to obtain an acceptable solution. In many cases it is only possible to calculate or to measure some macroscopic properties of fluids (pressure, temperature, molar volume, heat capacities...). The ideal gas “law,” PV = nRT, was one of the first important correlations of properties and the deviations from this law for real gases were usefully proposed. Moreover the statistical mechanics leads for example to the “hard-sphere” model providing the link between the transport properties and the molecular size and speed of the molecules. Further approximations take into account the intermolecular interactions (the potential functions) which can be used to describe attractions and repulsions. In any case thermodynamics reduces experimental or theoretical efforts by relating one physical property to another: the Clausius-Clapeyron equation provides a classical example of this method and the PVT function must be known accurately. However, in spite of the useful developments in molecular theory and computers technology, often it is usual to search for physical properties when the existing theories are not reliable and experimental data are not available: the required value of the physical or thermophysical property must be estimated or predicted (very often estimation and prediction are improperly used as synonymous). In some cases empirical correlations are useful, if it is clearly defined the range of conditions on which they are based. This work is concerned with dynamic viscosity µ and thermal conductivity λ and is based on clear and important rules to be respected
Code Verification of the HIGRAD Computational Fluid Dynamics Solver
Energy Technology Data Exchange (ETDEWEB)
Van Buren, Kendra L. [Los Alamos National Laboratory; Canfield, Jesse M. [Los Alamos National Laboratory; Hemez, Francois M. [Los Alamos National Laboratory; Sauer, Jeremy A. [Los Alamos National Laboratory
2012-05-04
The purpose of this report is to outline code and solution verification activities applied to HIGRAD, a Computational Fluid Dynamics (CFD) solver of the compressible Navier-Stokes equations developed at the Los Alamos National Laboratory, and used to simulate various phenomena such as the propagation of wildfires and atmospheric hydrodynamics. Code verification efforts, as described in this report, are an important first step to establish the credibility of numerical simulations. They provide evidence that the mathematical formulation is properly implemented without significant mistakes that would adversely impact the application of interest. Highly accurate analytical solutions are derived for four code verification test problems that exercise different aspects of the code. These test problems are referred to as: (i) the quiet start, (ii) the passive advection, (iii) the passive diffusion, and (iv) the piston-like problem. These problems are simulated using HIGRAD with different levels of mesh discretization and the numerical solutions are compared to their analytical counterparts. In addition, the rates of convergence are estimated to verify the numerical performance of the solver. The first three test problems produce numerical approximations as expected. The fourth test problem (piston-like) indicates the extent to which the code is able to simulate a 'mild' discontinuity, which is a condition that would typically be better handled by a Lagrangian formulation. The current investigation concludes that the numerical implementation of the solver performs as expected. The quality of solutions is sufficient to provide credible simulations of fluid flows around wind turbines. The main caveat associated to these findings is the low coverage provided by these four problems, and somewhat limited verification activities. A more comprehensive evaluation of HIGRAD may be beneficial for future studies.
Dynamics of a fluid flow on Mars: Lava or mud?
Wilson, Lionel; Mouginis-Mark, Peter J.
2014-05-01
A distinctive flow deposit southwest of Cerberus Fossae on Mars is analyzed. The flow source is a ∼20 m deep, ∼12 × 1.5 km wide depression within a yardang associated with the Medusae Fossae Formation. The flow traveled for ∼40 km following topographic lows to leave a deposit on average 3-4 km wide. The surface morphology of the deposit suggests that it was produced by the emplacement of a fluid flowing in a laminar fashion and possessing a finite yield strength. We use topographic data from a digital elevation model (DEM) to model the dynamics of the motion and infer that the fluid had a Bingham rheology with a plastic viscosity of ∼1 Pa s and a yield strength of ∼185 Pa. Although the low viscosity is consistent with the properties of komatiite-like lava, the combination of values of viscosity and yield strength, as well as the surface morphology of the flow, suggests that this was a mud flow. Comparison with published experimental data implies a solids content close to 60% by volume and a grain size dominated by silt-size particles. Comparison of the ∼1.5 km3 deposit volume with the ∼0.03 km3 volume of the source depression implies that ∼98% of the flow material was derived from depth in the crust. There are similarities between the deposit studied here, which we infer to be mud, and other flow deposits on Mars currently widely held to be lavas. This suggests that a re-appraisal of many of these deposits is now in order.
FOREWORD: Third International Symposium on Instability and Bifurcations in Fluid Dynamics
Bar-Yoseph, P. Z.; Brøns, M.; Cliffe, K. A.; Gelfgat, A.; Oron, A.
2010-01-01
Hydrodynamic stability is of fundamental importance in fluid dynamics and is a well-established subject of scientific investigation that continues to attract great interest of the fluid mechanics community. Bifurcations and instabilities are observed in all areas of fundamental and applied fluid dynamics and remain a challenge for experimental, theoretical and computational studies. Hydrodynamic instabilities of prototypical character are, for example, the Rayleigh-Bénard, the Taylor-Couette, the Bénard-Marangoni, the Rayleigh-Taylor, and the Kelvin-Helmholtz instabilities. A fundamental understanding of various patterns of bifurcations such as identifying the most dominant mechanisms responsible for the instability threshold is also required if one is to design reliable and efficient industrial processes and applications, such as melting, mixing, crystal growth, coating, welding, flow re-attachment over wings, and others. Modeling of various instability mechanisms in biological and biomedical systems is currently a very active and rapidly developing area of research with important biotechnological and medical applications (biofilm engineering, wound healing, etc). The understanding of breaking symmetry in hemodynamics could have important consequences for vascular biology and diseases and its implication for vascular interventions (grafting, stenting, etc). The collection of papers in this volume is a selection of the presentations given at the Third International Symposium on Instability and Bifurcations in Fluid Dynamics, University of Nottingham, UK, 10-13 August 2009. With more than 100 invited and contributed papers the symposium gave an overview of the state-of-the art of the field including experimental, theoretical, and computational approaches to problems related to convection, effects of magnetic fields, wake flows, rotating flows, and many others. The complete program can be found at the conference website. The symposium was the follow-up of two
A dynamic model for functional mapping of biological rhythms.
Fu, Guifang; Luo, Jiangtao; Berg, Arthur; Wang, Zhong; Li, Jiahan; Das, Kiranmoy; Li, Runze; Wu, Rongling
2011-01-01
Functional mapping is a statistical method for mapping quantitative trait loci (QTLs) that regulate the dynamic pattern of a biological trait. This method integrates mathematical aspects of biological complexity into a mixture model for genetic mapping and tests the genetic effects of QTLs by comparing genotype-specific curve parameters. As a way of quantitatively specifying the dynamic behavior of a system, differential equations have proven to be powerful for modeling and unraveling the biochemical, molecular, and cellular mechanisms of a biological process, such as biological rhythms. The equipment of functional mapping with biologically meaningful differential equations provides new insights into the genetic control of any dynamic processes. We formulate a new functional mapping framework for a dynamic biological rhythm by incorporating a group of ordinary differential equations (ODE). The Runge-Kutta fourth order algorithm was implemented to estimate the parameters that define the system of ODE. The new model will find its implications for understanding the interplay between gene interactions and developmental pathways in complex biological rhythms.
Scaling for Dynamical Systems in Biology.
Ledder, Glenn
2017-11-01
Asymptotic methods can greatly simplify the analysis of all but the simplest mathematical models and should therefore be commonplace in such biological areas as ecology and epidemiology. One essential difficulty that limits their use is that they can only be applied to a suitably scaled dimensionless version of the original dimensional model. Many books discuss nondimensionalization, but with little attention given to the problem of choosing the right scales and dimensionless parameters. In this paper, we illustrate the value of using asymptotics on a properly scaled dimensionless model, develop a set of guidelines that can be used to make good scaling choices, and offer advice for teaching these topics in differential equations or mathematical biology courses.
Drug screening in biological fluids - The need for a systematic approach
de Zeeuw, R.A
1997-01-01
In this paper the key steps towards drug screening in biological fluids are considered: (i) sample work up-isolation-concentration: (ii) differentiation-detection; (iii) identification. For (i) solid-phase extraction has very good potential; for (ii) thin-layer chromatography, gas chromatography and
Knotted solutions for linear and nonlinear theories: Electromagnetism and fluid dynamics
Daniel W.F. Alves; Carlos Hoyos; Horatiu Nastase; Jacob Sonnenschein
2017-01-01
We examine knotted solutions, the most simple of which is the "Hopfion", from the point of view of relations between electromagnetism and ideal fluid dynamics. A map between fluid dynamics and electromagnetism works for initial conditions or for linear perturbations, allowing us to find new knotted fluid solutions. Knotted solutions are also found to to be solutions of nonlinear generalizations of electromagnetism, and of quantum-corrected actions for electromagnetism coupled to other modes. ...
Xiang, J; Tutino, V M; Snyder, K V; Meng, H
2014-10-01
Image-based computational fluid dynamics holds a prominent position in the evaluation of intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current computational fluid dynamics findings correlating both high and low wall shear stress with intracranial aneurysm growth and rupture puzzle researchers and clinicians alike. These conflicting findings may stem from inconsistent parameter definitions, small datasets, and intrinsic complexities in intracranial aneurysm growth and rupture. In Part 1 of this 2-part review, we proposed a unifying hypothesis: both high and low wall shear stress drive intracranial aneurysm growth and rupture through mural cell-mediated and inflammatory cell-mediated destructive remodeling pathways, respectively. In the present report, Part 2, we delineate different wall shear stress parameter definitions and survey recent computational fluid dynamics studies, in light of this mechanistic heterogeneity. In the future, we expect that larger datasets, better analyses, and increased understanding of hemodynamic-biologic mechanisms will lead to more accurate predictive models for intracranial aneurysm risk assessment from computational fluid dynamics. © 2014 by American Journal of Neuroradiology.
Dynamic modeling of fluid power transmissions for wind turbines
Diepeveen, N.F.B.; Jarquin Laguna, A.
2011-01-01
Fluid power transmission for wind turbines is quietly gaining more ground/interest. The principle of the various concepts presented so far is to convert aerodynamic torque of the rotor blades into a pressurized fluid flow by means of a positive displacement pump. At the other end of the fluid power
International Nuclear Information System (INIS)
Sagawa, Hiroyuki; Holzwarth, G.
1978-01-01
Small amplitude vibrations of spherical nuclei are considered in microscopic (RPA) and fluid-dynamical description. Assuming the concentration of transition strength into one collective state, the microscopic result can be brought into close analogy to constrained fluid-dynamical motion. The decisive difference occurs in the contribution of the microscopic kinetic energy to the collective potential energy. It is shown that extension of fluid dynamics to include dynamical distortions of the local Fermi surface is sufficient to reproduce the microscopic results. Numerical examples are given for L=0 and L=2 isoscalar modes for a Skyrme-type nucleon-nucleon force. (auth.)
Dynamical effect of confining wall on diffusion of fluid at nanoscale
International Nuclear Information System (INIS)
Devi, Reena; Srivastava, Sunita; Tankeshwar, K.
2016-01-01
The dynamical effect of wall-fluid interaction on diffusion in direction perpendicular to confining walls has been studied, theoretically. The properties of fluids which incorporates the effect of static changes in confined fluid has been modified to include, directly, the dynamical effects of wall on the motion of particles. The results obtained for VACF in perpendicular direction of channel of width of two atomic diameters are presented and compared with the molecular dynamic (MD) simulation results as well as the results obtained without including the dynamical effect.
Banking of biological fluids for studies of disease-associated protein biomarkers
DEFF Research Database (Denmark)
Rasmussen, Anne-Sofie Schrohl; Würtz, Sidse Ørnbjerg; Kohn, Elise
2008-01-01
With the increasing demand of providing personalized medicine the need for biobanking of biological material from individual patients has increased. Such samples are essential for molecular research aimed at characterizing diseases at several levels ranging from epidemiology and diagnostic...... and as a surrogate response marker. Many types of biological fluids or tissues can be collected and stored in biorepositories. Samples of blood can be further processed into plasma and serum, and tissue pieces can be either frozen or fixed in formalin and then embedded into paraffin. The present review focuses...... on biological fluids, especially serum and plasma, intended for study of protein biomarkers. In biomarker studies the process from the decision to take a sample from an individual to the moment the sample is safely placed in the biobank consists of several phases including collection of samples, transport...
Tribological performance of the biological components of synovial fluid in artificial joint implants
Ghosh, Subir; Choudhury, Dipankar; Roy, Taposh; Moradi, Ali; Masjuki, H H; Pingguan-Murphy, Belinda
2015-01-01
The concentration of biological components of synovial fluid (such as albumin, globulin, hyaluronic acid, and lubricin) varies between healthy persons and osteoarthritis (OA) patients. The aim of the present study is to compare the effects of such variation on tribological performance in a simulated hip joint model. The study was carried out experimentally by utilizing a pin-on-disk simulator on ceramic-on-ceramic (CoC) and ceramic-on-polyethylene (CoP) hip joint implants. The experimental results show that both friction and wear of artificial joints fluctuate with the concentration level of biological components. Moreover, the performance also varies between material combinations. Wear debris sizes and shapes produced by ceramic and polyethylene were diverse. We conclude that the biological components of synovial fluid and their concentrations should be considered in order to select an artificial hip joint to best suit that patient. PMID:27877822
Computational Fluid Dynamics Analysis of Flexible Duct Junction Box Design
Energy Technology Data Exchange (ETDEWEB)
Beach, Robert [IBACOS Inc., Pittsburgh, PA (United States); Prahl, Duncan [IBACOS Inc., Pittsburgh, PA (United States); Lange, Rich [IBACOS Inc., Pittsburgh, PA (United States)
2013-12-01
IBACOS explored the relationships between pressure and physical configurations of flexible duct junction boxes by using computational fluid dynamics (CFD) simulations to predict individual box parameters and total system pressure, thereby ensuring improved HVAC performance. Current Air Conditioning Contractors of America (ACCA) guidance (Group 11, Appendix 3, ACCA Manual D, Rutkowski 2009) allows for unconstrained variation in the number of takeoffs, box sizes, and takeoff locations. The only variables currently used in selecting an equivalent length (EL) are velocity of air in the duct and friction rate, given the first takeoff is located at least twice its diameter away from the inlet. This condition does not account for other factors impacting pressure loss across these types of fittings. For each simulation, the IBACOS team converted pressure loss within a box to an EL to compare variation in ACCA Manual D guidance to the simulated variation. IBACOS chose cases to represent flows reasonably correlating to flows typically encountered in the field and analyzed differences in total pressure due to increases in number and location of takeoffs, box dimensions, and velocity of air, and whether an entrance fitting is included. The team also calculated additional balancing losses for all cases due to discrepancies between intended outlet flows and natural flow splits created by the fitting. In certain asymmetrical cases, the balancing losses were significantly higher than symmetrical cases where the natural splits were close to the targets. Thus, IBACOS has shown additional design constraints that can ensure better system performance.
Improving flow distribution in influent channels using computational fluid dynamics.
Park, No-Suk; Yoon, Sukmin; Jeong, Woochang; Lee, Seungjae
2016-10-01
Although the flow distribution in an influent channel where the inflow is split into each treatment process in a wastewater treatment plant greatly affects the efficiency of the process, and a weir is the typical structure for the flow distribution, to the authors' knowledge, there is a paucity of research on the flow distribution in an open channel with a weir. In this study, the influent channel of a real-scale wastewater treatment plant was used, installing a suppressed rectangular weir that has a horizontal crest to cross the full channel width. The flow distribution in the influent channel was analyzed using a validated computational fluid dynamics model to investigate (1) the comparison of single-phase and two-phase simulation, (2) the improved procedure of the prototype channel, and (3) the effect of the inflow rate on flow distribution. The results show that two-phase simulation is more reliable due to the description of the free-surface fluctuations. It should first be considered for improving flow distribution to prevent a short-circuit flow, and the difference in the kinetic energy with the inflow rate makes flow distribution trends different. The authors believe that this case study is helpful for improving flow distribution in an influent channel.
Shape Optimization of Vehicle Radiator Using Computational Fluid Dynamics (cfd)
Maddipatla, Sridhar; Guessous, Laila
2002-11-01
Automotive manufacturers need to improve the efficiency and lifetime of all engine components. In the case of radiators, performance depends significantly on coolant flow homogeneity across the tubes and overall pressure drop between the inlet and outlet. Design improvements are especially needed in tube-flow uniformity to prevent premature fouling and failure of heat exchangers. Rather than relying on ad-hoc geometry changes, the current study combines Computational Fluid Dynamics with shape optimization methods to improve radiator performance. The goal is to develop an automated suite of virtual tools to assist in radiator design. Two objective functions are considered: a flow non-uniformity coefficient,Cf, and the overall pressure drop, dP*. The methodology used to automate the CFD and shape optimization procedures is discussed. In the first phase, single and multi-variable optimization methods, coupled with CFD, are applied to simplified 2-D radiator models to investigate effects of inlet and outlet positions on the above functions. The second phase concentrates on CFD simulations of a simplified 3-D radiator model. The results, which show possible improvements in both pressure and flow uniformity, validate the optimization criteria that were developed, as well as the potential of shape optimization methods with CFD to improve heat exchanger design. * Improving Radiator Design Through Shape Optimization, L. Guessous and S. Maddipatla, Paper # IMECE2002-33888, Proceedings of the 2002 ASME International Mechanical Engineering Congress and Exposition, November 2002
The Fluid Dynamical Limits of the Linearized Boltzmann Equation.
Campini, Marco
The old question concerning the mathematical formulation of the fluid dynamic limits of kinetic theory is examined by studying the solution of the Cauchy problem for two differently scaled linearized Boltzmann equations on periodic domain as the mean free path of the particles becomes small. Under minimal assumptions on the initial data, by using an a priori estimate, it is possible, in a Hilbert space functional frame, to prove the weak convergence of solutions toward a function that has the form of an infinitesimal maxwellian in the velocity variable. The velocity moments of this function are then proved to satisfy either the linearized Euler or the Stokes system of equations (depending on the chosen scaling), by passing to the limit in the conservation relations derived from the Boltzmann equation. A theorem injecting continuously the intersection of certain weak spaces into a normed one is proved. Together with properties of the Euler semigroup, this allows to show strong convergence of the first three moments of the distribution function toward the macroscopic quantities density, bulk velocity and temperature, solutions of the linearized Euler system. The Stokes case is treated somewhat differently, through the introduction of a result, proved by using the adjoint formulation for linear kinetic equations, that extends the averaging theory of Golse-Lions-Perthame-Sentis. The desired convergence for the divergence-free component of the second moment toward the macroscopic velocity is then shown.
High-order computational fluid dynamics tools for aircraft design.
Wang, Z J
2014-08-13
Most forecasts predict an annual airline traffic growth rate between 4.5 and 5% in the foreseeable future. To sustain that growth, the environmental impact of aircraft cannot be ignored. Future aircraft must have much better fuel economy, dramatically less greenhouse gas emissions and noise, in addition to better performance. Many technical breakthroughs must take place to achieve the aggressive environmental goals set up by governments in North America and Europe. One of these breakthroughs will be physics-based, highly accurate and efficient computational fluid dynamics and aeroacoustics tools capable of predicting complex flows over the entire flight envelope and through an aircraft engine, and computing aircraft noise. Some of these flows are dominated by unsteady vortices of disparate scales, often highly turbulent, and they call for higher-order methods. As these tools will be integral components of a multi-disciplinary optimization environment, they must be efficient to impact design. Ultimately, the accuracy, efficiency, robustness, scalability and geometric flexibility will determine which methods will be adopted in the design process. This article explores these aspects and identifies pacing items. © 2014 The Author(s) Published by the Royal Society. All rights reserved.
Effective particle size from molecular dynamics simulations in fluids
Ju, Jianwei; Welch, Paul M.; Rasmussen, Kim Ø.; Redondo, Antonio; Vorobieff, Peter; Kober, Edward M.
2018-04-01
We report molecular dynamics simulations designed to investigate the effective size of colloidal particles suspended in a fluid in the vicinity of a rigid wall where all interactions are defined by smooth atomic potential functions. These simulations are used to assess how the behavior of this system at the atomistic length scale compares to continuum mechanics models. In order to determine the effective size of the particles, we calculate the solvent forces on spherical particles of different radii as a function of different positions near and overlapping with the atomistically defined wall and compare them to continuum models. This procedure also then determines the effective position of the wall. Our analysis is based solely on forces that the particles sense, ensuring self-consistency of the method. The simulations were carried out using both Weeks-Chandler-Andersen and modified Lennard-Jones (LJ) potentials to identify the different contributions of simple repulsion and van der Waals attractive forces. Upon correction for behavior arising the discreteness of the atomic system, the underlying continuum physics analysis appeared to be correct down to much less than the particle radius. For both particle types, the effective radius was found to be ˜ 0.75σ , where σ defines the length scale of the force interaction (the LJ diameter). The effective "hydrodynamic" radii determined by this means are distinct from commonly assumed values of 0.5σ and 1.0σ , but agree with a value developed from the atomistic analysis of the viscosity of such systems.
A Review of Hemolysis Prediction Models for Computational Fluid Dynamics.
Yu, Hai; Engel, Sebastian; Janiga, Gábor; Thévenin, Dominique
2017-07-01
Flow-induced hemolysis is a crucial issue for many biomedical applications; in particular, it is an essential issue for the development of blood-transporting devices such as left ventricular assist devices, and other types of blood pumps. In order to estimate red blood cell (RBC) damage in blood flows, many models have been proposed in the past. Most models have been validated by their respective authors. However, the accuracy and the validity range of these models remains unclear. In this work, the most established hemolysis models compatible with computational fluid dynamics of full-scale devices are described and assessed by comparing two selected reference experiments: a simple rheometric flow and a more complex hemodialytic flow through a needle. The quantitative comparisons show very large deviations concerning hemolysis predictions, depending on the model and model parameter. In light of the current results, two simple power-law models deliver the best compromise between computational efficiency and obtained accuracy. Finally, hemolysis has been computed in an axial blood pump. The reconstructed geometry of a HeartMate II shows that hemolysis occurs mainly at the tip and leading edge of the rotor blades, as well as at the leading edge of the diffusor vanes. © 2017 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
Cepstrum analysis and applications to computational fluid dynamic solutions
Meadows, Kristine R.
1990-04-01
A novel approach to the problem of spurious reflections introduced by artificial boundary conditions in computational fluid dynamic (CFD) solutions is proposed. Instead of attempting to derive non-reflecting boundary conditions, the approach is to accept the fact that spurious reflections occur, but to remove these reflections with cepstrum analysis, a signal processing technique which has been successfully used to remove echoes from experimental data. First, the theory of the cepstrum method is presented. This includes presentation of two types of cepstra: The Power Cepstrum and the Complex Cepstrum. The definitions of the cepstrum methods are applied theoretically and numerically to the analytical solution of sinusoidal plane wave propagation in a duct. One-D and 3-D time dependent solutions to the Euler equations are computed, and hard-wall conditions are prescribed at the numerical boundaries. The cepstrum method is applied, and the reflections from the boundaries are removed from the solutions. One-D and 3-D solutions are computed with so called nonreflecting boundary conditions, and these solutions are compared to those obtained by prescribing hard wall conditions and processing with the cepstrum.
Fluid Dynamics of Thrombosis in Transcatheter Aortic Valves
Seo, Jung Hee; Zhu, Chi; Dou, Zhongwang; Resar, Jon; Mittal, Rajat
2017-11-01
Transcatheter aortic valve replacement (TAVR) with bioprosthetic valves (BPV) has become highly prevalent in recent years. While one advantage of BPVs over mechanical ones is the lower incidence of valve thrombosis, recent clinical studies have suggested a higher than expected incidence of subclinical bioprosthetic valve thrombosis (BVT). Many factors that might affect the transvalvular hemodynamics including the valve position, orientation, stent, and interaction with the coronary flow, have been suggested, but the casual mechanisms of valve thrombosis are still unknown. In the present study, the hemodynamics associated with the formation of BVT is investigated using a novel, coupled flow-structure-biochemical computational modeling. A reduced degree of freedom, fluid-structure-interaction model is proposed for the efficient simulation of the hemodynamics and leaflet dynamics in the BPVs. Simple models to take into account the effects of the stent and coronary flows have also been developed. Simulations are performed for canonical models of BPVs in the aorta in various configurations and the results are examined to provide insights into the mechanisms for valve thrombosis. Supported by the NSF Grants IIS-1344772, CBET-1511200 and NSF XSEDE Grant TG-CTS100002.
Computational Fluid Dynamics Modeling of Flow over Stepped Spillway
Directory of Open Access Journals (Sweden)
Raad Hoobi Irzooki
2017-12-01
Full Text Available In present paper, the computational fluid dynamics (CFD - program Flow-3D was used toanalyze and study the characteristics of flow energy dissipation over stepped spillways. Threedifferent spillway heights ( (15, 20 and 25cm were used. For each one of these models, threenumbers of steps (N (5, 10 and 25 and three spillway slopes (S (0.5, 1 and 1.25 were used.Eight different discharges ranging (600-8500cm³/s were passed over each one of these models,therefore the total runs of this study are 216. The energy dissipation over these models and thepressure distribution on the horizontal and vertical step faces over some models were studied. Forverification purpose of the (CFD program, the experimental work was conducted on four models ofstepped spillway and five different discharges were passed over each model. The magnitude ofdissipated energy on models was compared with results of numerical program under sameconditions. The comparison showed good agreement between them with standard percentage errorranging between (-2.01 - 11.13%. Thus, the program Flow-3D is a reasonable numerical programwhich can be used in this study.Results showed that the energy dissipation increases with increased spillway height anddecreased number of steps and spillway slope. Also, the energy dissipation decreases withincreasing the flow rate. An empirical equation for measuring the energy dissipation was derivedusing the dimensional analysis. The coefficient of determination of this equation ( equals 0.766.
Computational fluid dynamics modeling of proton exchange membrane fuel cells
Energy Technology Data Exchange (ETDEWEB)
UM,SUKKEE; WANG,C.Y.; CHEN,KEN S.
2000-02-11
A transient, multi-dimensional model has been developed to simulate proton exchange membrane (PEM) fuel cells. The model accounts simultaneously for electrochemical kinetics, current distribution, hydrodynamics and multi-component transport. A single set of conservation equations valid for flow channels, gas-diffusion electrodes, catalyst layers and the membrane region are developed and numerically solved using a finite-volume-based computational fluid dynamics (CFD) technique. The numerical model is validated against published experimental data with good agreement. Subsequently, the model is applied to explore hydrogen dilution effects in the anode feed. The predicted polarization cubes under hydrogen dilution conditions are found to be in qualitative agreement with recent experiments reported in the literature. The detailed two-dimensional electrochemical and flow/transport simulations further reveal that in the presence of hydrogen dilution in the fuel stream, hydrogen is depleted at the reaction surface resulting in substantial kinetic polarization and hence a lower current density that is limited by hydrogen transport from the fuel stream to the reaction site.
Effective particle size from molecular dynamics simulations in fluids
Ju, Jianwei; Welch, Paul M.; Rasmussen, Kim Ø.; Redondo, Antonio; Vorobieff, Peter; Kober, Edward M.
2017-12-01
We report molecular dynamics simulations designed to investigate the effective size of colloidal particles suspended in a fluid in the vicinity of a rigid wall where all interactions are defined by smooth atomic potential functions. These simulations are used to assess how the behavior of this system at the atomistic length scale compares to continuum mechanics models. In order to determine the effective size of the particles, we calculate the solvent forces on spherical particles of different radii as a function of different positions near and overlapping with the atomistically defined wall and compare them to continuum models. This procedure also then determines the effective position of the wall. Our analysis is based solely on forces that the particles sense, ensuring self-consistency of the method. The simulations were carried out using both Weeks-Chandler-Andersen and modified Lennard-Jones (LJ) potentials to identify the different contributions of simple repulsion and van der Waals attractive forces. Upon correction for behavior arising the discreteness of the atomic system, the underlying continuum physics analysis appeared to be correct down to much less than the particle radius. For both particle types, the effective radius was found to be ˜ 0.75σ , where σ defines the length scale of the force interaction (the LJ diameter). The effective "hydrodynamic" radii determined by this means are distinct from commonly assumed values of 0.5σ and 1.0σ , but agree with a value developed from the atomistic analysis of the viscosity of such systems.
Class of reconstructed discontinuous Galerkin methods in computational fluid dynamics
International Nuclear Information System (INIS)
Luo, Hong; Xia, Yidong; Nourgaliev, Robert
2011-01-01
A class of reconstructed discontinuous Galerkin (DG) methods is presented to solve compressible flow problems on arbitrary grids. The idea is to combine the efficiency of the reconstruction methods in finite volume methods and the accuracy of the DG methods to obtain a better numerical algorithm in computational fluid dynamics. The beauty of the resulting reconstructed discontinuous Galerkin (RDG) methods is that they provide a unified formulation for both finite volume and DG methods, and contain both classical finite volume and standard DG methods as two special cases of the RDG methods, and thus allow for a direct efficiency comparison. Both Green-Gauss and least-squares reconstruction methods and a least-squares recovery method are presented to obtain a quadratic polynomial representation of the underlying linear discontinuous Galerkin solution on each cell via a so-called in-cell reconstruction process. The devised in-cell reconstruction is aimed to augment the accuracy of the discontinuous Galerkin method by increasing the order of the underlying polynomial solution. These three reconstructed discontinuous Galerkin methods are used to compute a variety of compressible flow problems on arbitrary meshes to assess their accuracy. The numerical experiments demonstrate that all three reconstructed discontinuous Galerkin methods can significantly improve the accuracy of the underlying second-order DG method, although the least-squares reconstructed DG method provides the best performance in terms of both accuracy, efficiency, and robustness. (author)
Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
Directory of Open Access Journals (Sweden)
Taha M Mehemed
Full Text Available Oxygen causes an increase in the longitudinal relaxation rate of tissues through its T1-shortening effect owing to its paramagnetic properties. Due to such effects, MRI has been used to study oxygen-related signal intensity changes in various body parts including cerebrospinal fluid (CSF space. Oxygen enhancement of CSF has been mainly studied using MRI sequences with relatively longer time resolution such as FLAIR, and T1 value calculation. In this study, fifteen healthy volunteers were scanned using fast advanced spin echo MRI sequence with and without inversion recovery pulse in order to dynamically track oxygen enhancement of CSF. We also focused on the differences of oxygen enhancement at sulcal and ventricular CSF. Our results revealed that CSF signal after administration of oxygen shows rapid signal increase in both sulcal CSF and ventricular CSF on both sequences, with statistically significant predominant increase in sulcal CSF compared with ventricular CSF. CSF is traditionally thought to mainly form from the choroid plexus in the ventricles and is absorbed at the arachnoid villi, however, it is also believed that cerebral arterioles contribute to the production and absorption of CSF, and controversy remains in terms of the precise mechanism. Our results demonstrated rapid oxygen enhancement in sulcal CSF, which may suggest inhaled oxygen may diffuse into sulcal CSF space rapidly probably due to the abundance of pial arterioles on the brain sulci.
Computational fluid dynamic analysis for independent floating water treatment device
Zawawi, M. H.; Swee, M. G.; Zainal, N. S.; Zahari, N. M.; Kamarudin, M. A.; Ramli, M. Z.
2017-09-01
This project is to design and develop 3D Independent Floating Water Treatment Device using 3D CAD software. The device is designed to treat water for better water qualities and water flows of the lakes. A prototype was manufactured to study the water treatment efficiency of the device. Computational Fluid Dynamic (CFD) analysis was used to capture the efficiency of the Independent Floating Water Treatment Device by simulates and model the water flows, pressure and velocity. According to the results, the maximum velocity magnitude was around 1m3/s. The velocity contour showed the device has high velocity at the pipe outlet. The velocity became lower and lower as the distance is further from the pipe outlet. The result from the velocity measurement was 1.05m/s. The pressure magnitude was in between 1426 Pa to 1429 Pa. The laboratory results based on water parameters proved that the water movement and direction of water flow of the Independent Floating Water Treatment Device enable the efficient pollutant removal. The vector plot, velocity contour, water flow path lines, water flow streamline and pressure contour was successful modeled.
Algorithms for computational fluid dynamics n parallel processors
International Nuclear Information System (INIS)
Van de Velde, E.F.
1986-01-01
A study of parallel algorithms for the numerical solution of partial differential equations arising in computational fluid dynamics is presented. The actual implementation on parallel processors of shared and nonshared memory design is discussed. The performance of these algorithms is analyzed in terms of machine efficiency, communication time, bottlenecks and software development costs. For elliptic equations, a parallel preconditioned conjugate gradient method is described, which has been used to solve pressure equations discretized with high order finite elements on irregular grids. A parallel full multigrid method and a parallel fast Poisson solver are also presented. Hyperbolic conservation laws were discretized with parallel versions of finite difference methods like the Lax-Wendroff scheme and with the Random Choice method. Techniques are developed for comparing the behavior of an algorithm on different architectures as a function of problem size and local computational effort. Effective use of these advanced architecture machines requires the use of machine dependent programming. It is shown that the portability problems can be minimized by introducing high level operations on vectors and matrices structured into program libraries
Simulation of climate inside tunnel greenhouses using computational fluid dynamics
Energy Technology Data Exchange (ETDEWEB)
Zeroual, S.; Bougoul, S.; Labaal, C.; Aouachria, Z. [Batna Univ., Batna (Algeria). Dept. of Physics
2009-07-01
This paper investigated heat transfer and air flow in an open-tunnel greenhouse both with and without plants. The aim of the study was to determine the effect of wind speed on natural ventilation using computational fluid dynamics (CFD) and finite volume methods. A porous medium approach was used to to describe air flow. Turbulence in the 3-D model was described using a standard k-{epsilon} model. Air temperature variations indicated the presence of a gradient from the side walls towards the centre of the greenhouse. The gradient was caused by the movement of hot air rising towards the roof vents. A vertical gradient was attributed to the movement of the air above the surface of the heated floor. Maximum air velocity was reached at the openings of the greenhouse. The lowest heat values were measured in the middle of the greenhouse and at the crop level. Results obtained in the study were compared with results obtained in the literature. Data obtained in the study will be used to improve the design and control of both greenhouse ventilation and heating systems. 15 refs., 18 figs.
Computational fluid dynamics for turbomachinery internal air systems.
Chew, John W; Hills, Nicholas J
2007-10-15
Considerable progress in development and application of computational fluid dynamics (CFD) for aeroengine internal flow systems has been made in recent years. CFD is regularly used in industry for assessment of air systems, and the performance of CFD for basic axisymmetric rotor/rotor and stator/rotor disc cavities with radial throughflow is largely understood and documented. Incorporation of three-dimensional geometrical features and calculation of unsteady flows are becoming commonplace. Automation of CFD, coupling with thermal models of the solid components, and extension of CFD models to include both air system and main gas path flows are current areas of development. CFD is also being used as a research tool to investigate a number of flow phenomena that are not yet fully understood. These include buoyancy-affected flows in rotating cavities, rim seal flows and mixed air/oil flows. Large eddy simulation has shown considerable promise for the buoyancy-driven flows and its use for air system flows is expected to expand in the future.
Computational fluid dynamics benchmark dataset of airflow in tracheas
Directory of Open Access Journals (Sweden)
A.J. Bates
2017-02-01
Full Text Available Computational Fluid Dynamics (CFD is fast becoming a useful tool to aid clinicians in pre-surgical planning through the ability to provide information that could otherwise be extremely difficult if not impossible to obtain. However, in order to provide clinically relevant metrics, the accuracy of the computational method must be sufficiently high. There are many alternative methods employed in the process of performing CFD simulations within the airways, including different segmentation and meshing strategies, as well as alternative approaches to solving the Navier–Stokes equations. However, as in vivo validation of the simulated flow patterns within the airways is not possible, little exists in the way of validation of the various simulation techniques. The data presented here consists of very highly resolved flow data. The degree of resolution is compared to the highest necessary resolutions of the Kolmogorov length and time scales. Therefore this data is ideally suited to act as a benchmark case to which cheaper computational methods may be compared. A dataset and solution setup for one such more efficient method, large eddy simulation (LES, is also presented.
DEFF Research Database (Denmark)
Larsson, Hilde Kristina
Computational fluid dynamics (CFD) is the application of numerical methods to solve systems of partial differential equations related to fluid dynamics. The continuity and the momentum equations are the most commonly applied equations within CFD, and together they can be used to calculate...... the velocity and pressure distributions in a fluid. CFD also enables the modelling of several fluids simultaneously, e.g. gas bubbles in a liquid, as well as the presence of turbulence and dissolved chemicals in a fluid, and many other phenomena. This makes CFD an appreciated tool for studying flow structures...... and an ion-exchange reaction are also modelled and compared to experimental data. The thesis includes a comprehensive overview of the fundamentals behind a CFD software, as well as a more detailed review of the fluid dynamic phenomena investigated in this project. The momentum and continuity equations...
Experimental investigation of unsteady fluid dynamic forces acting on tube array
International Nuclear Information System (INIS)
Tanaka, Hiroki; Takahara, Shigeru; Tanaka, Mitsutoshi
1981-01-01
It is well-known that the cylinder bundle vibrates in cross flow. Many studies of the vibration have been made, and it has been clarified that the vibration is caused by fluid-elastic vibration coupling to neighboring cylinders. The theory given in this paper considers unsteady fluid dynamic forces to be composed of inertia forces due to added mass of fluid, damping forces of fluid which are in phase to cylinder vibrating velocity, and stiffness forces which are proportional to cylinder displacements. Furthermore, taking account of the influences of neighboring cylinder vibrations, ten kinds of unsteady fluid dynamic forces are considered to act on a cylinder in cylinder bundles. Equations of motion of cylinders were deduced and the critical velocities were calculated with the measured unsteady fluid dynamic forces. Critical velocity tests were also conducted with cylinders which were supported with elastic spars. The calculated critical velocities coincided well with the test results. (author)
Image-based computational fluid dynamics in the lung: virtual reality or new clinical practice?
Burrowes, Kelly S; De Backer, Jan; Kumar, Haribalan
2017-11-01
The development and implementation of personalized medicine is paramount to improving the efficiency and efficacy of patient care. In the respiratory system, function is largely dictated by the choreographed movement of air and blood to the gas exchange surface. The passage of air begins in the upper airways, either via the mouth or nose, and terminates at the alveolar interface, while blood flows from the heart to the alveoli and back again. Computational fluid dynamics (CFD) is a well-established tool for predicting fluid flows and pressure distributions within complex systems. Traditionally CFD has been used to aid in the effective or improved design of a system or device; however, it has become increasingly exploited in biological and medical-based applications further broadening the scope of this computational technique. In this review, we discuss the advancement in application of CFD to the respiratory system and the contributions CFD is currently making toward improving precision medicine. The key areas CFD has been applied to in the pulmonary system are in predicting fluid transport and aerosol distribution within the airways. Here we focus our discussion on fluid flows and in particular on image-based clinically focused CFD in the ventilatory system. We discuss studies spanning from the paranasal sinuses through the conducting airways down to the level of the alveolar airways. The combination of imaging and CFD is enabling improved device design in aerosol transport, improved biomarkers of lung function in clinical trials, and improved predictions and assessment of surgical interventions in the nasal sinuses. WIREs Syst Biol Med 2017, 9:e1392. doi: 10.1002/wsbm.1392 For further resources related to this article, please visit the WIREs website. © 2017 Wiley Periodicals, Inc.
A stochastic immersed boundary method for fluid-structure dynamics at microscopic length scales
International Nuclear Information System (INIS)
Atzberger, Paul J.; Kramer, Peter R.; Peskin, Charles S.
2007-01-01
In modeling many biological systems, it is important to take into account flexible structures which interact with a fluid. At the length scale of cells and cell organelles, thermal fluctuations of the aqueous environment become significant. In this work, it is shown how the immersed boundary method of [C.S. Peskin, The immersed boundary method, Acta Num. 11 (2002) 1-39.] for modeling flexible structures immersed in a fluid can be extended to include thermal fluctuations. A stochastic numerical method is proposed which deals with stiffness in the system of equations by handling systematically the statistical contributions of the fastest dynamics of the fluid and immersed structures over long time steps. An important feature of the numerical method is that time steps can be taken in which the degrees of freedom of the fluid are completely underresolved, partially resolved, or fully resolved while retaining a good level of accuracy. Error estimates in each of these regimes are given for the method. A number of theoretical and numerical checks are furthermore performed to assess its physical fidelity. For a conservative force, the method is found to simulate particles with the correct Boltzmann equilibrium statistics. It is shown in three dimensions that the diffusion of immersed particles simulated with the method has the correct scaling in the physical parameters. The method is also shown to reproduce a well-known hydrodynamic effect of a Brownian particle in which the velocity autocorrelation function exhibits an algebraic (τ -3/2 ) decay for long times [B.J. Alder, T.E. Wainwright, Decay of the Velocity Autocorrelation Function, Phys. Rev. A 1(1) (1970) 18-21]. A few preliminary results are presented for more complex systems which demonstrate some potential application areas of the method. Specifically, we present simulations of osmotic effects of molecular dimers, worm-like chain polymer knots, and a basic model of a molecular motor immersed in fluid subject to a
AC Calorimetric Design for Dynamic of Biological Materials
Shigeo Imaizumi
2006-01-01
We developed a new AC calorimeter for the measurement of dynamic specific heat capacity in liquids, including aqueous suspensions of biological materials. This method has several advantages. The first is that a high-resolution measurement of heat capacity, inmillidegrees, can be performed as a function of temperature, even with a very small sample. Therefore, AC calorimeter is a powerful tool to study critical behavior a tphase transition in biological materials. The second advantage is that ...
Biological Implications of Dynamical Phases in Non-equilibrium Networks
Murugan, Arvind; Vaikuntanathan, Suriyanarayanan
2016-03-01
Biology achieves novel functions like error correction, ultra-sensitivity and accurate concentration measurement at the expense of free energy through Maxwell Demon-like mechanisms. The design principles and free energy trade-offs have been studied for a variety of such mechanisms. In this review, we emphasize a perspective based on dynamical phases that can explain commonalities shared by these mechanisms. Dynamical phases are defined by typical trajectories executed by non-equilibrium systems in the space of internal states. We find that coexistence of dynamical phases can have dramatic consequences for function vs free energy cost trade-offs. Dynamical phases can also provide an intuitive picture of the design principles behind such biological Maxwell Demons.
Applying differential dynamic logic to reconfigurable biological networks.
Figueiredo, Daniel; Martins, Manuel A; Chaves, Madalena
2017-09-01
Qualitative and quantitative modeling frameworks are widely used for analysis of biological regulatory networks, the former giving a preliminary overview of the system's global dynamics and the latter providing more detailed solutions. Another approach is to model biological regulatory networks as hybrid systems, i.e., systems which can display both continuous and discrete dynamic behaviors. Actually, the development of synthetic biology has shown that this is a suitable way to think about biological systems, which can often be constructed as networks with discrete controllers, and present hybrid behaviors. In this paper we discuss this approach as a special case of the reconfigurability paradigm, well studied in Computer Science (CS). In CS there are well developed computational tools to reason about hybrid systems. We argue that it is worth applying such tools in a biological context. One interesting tool is differential dynamic logic (dL), which has recently been developed by Platzer and applied to many case-studies. In this paper we discuss some simple examples of biological regulatory networks to illustrate how dL can be used as an alternative, or also as a complement to methods already used. Copyright © 2017 Elsevier Inc. All rights reserved.
International Nuclear Information System (INIS)
Donea, J.; Giuliani, S.
1989-01-01
Finite element models, implemented in the computed code EURDYN-3M, are presented for the prediction of the non-linear response of three-dimensional fluid-structure systems exposed to transient dynamic loading. An arbitrary Lagrangian-Eulerian kinematical description of the fluid domain is adopted in which the grid points can be displaced independently of the fluid motion. This formulation leads to an easy and accurate treatment of fluid-structure interfaces and permits significant fluid sloshing and swirling to occur without producing excessive distorsions of the computational mesh. Two numerical examples are presented to illustrate the potential of the proposed modelling procedures
Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET.
de Leon, Mony J; Li, Yi; Okamura, Nobuyuki; Tsui, Wai H; Saint-Louis, Les A; Glodzik, Lidia; Osorio, Ricardo S; Fortea, Juan; Butler, Tracy; Pirraglia, Elizabeth; Fossati, Silvia; Kim, Hee-Jin; Carare, Roxana O; Nedergaard, Maiken; Benveniste, Helene; Rusinek, Henry
2017-09-01
Evidence supporting the hypothesis that reduced cerebrospinal fluid (CSF) clearance is involved in the pathophysiology of Alzheimer disease (AD) comes primarily from rodent models. However, unlike rodents, in which predominant extracranial CSF egress is via olfactory nerves traversing the cribriform plate, human CSF clearance pathways are not well characterized. Dynamic PET with 18 F-THK5117, a tracer for tau pathology, was used to estimate the ventricular CSF time-activity as a biomarker for CSF clearance. We tested 3 hypotheses: extracranial CSF is detected at the superior turbinates; CSF clearance is reduced in AD; and CSF clearance is inversely associated with amyloid deposition. Methods: Fifteen subjects, 8 with AD and 7 normal control volunteers, were examined with 18 F-THK5117. Ten subjects additionally underwent 11 C-Pittsburgh compound B ( 11 C-PiB) PET scanning, and 8 were 11 C-PiB-positive. Ventricular time-activity curves of 18 F-THK5117 were used to identify highly correlated time-activity curves from extracranial voxels. Results: For all subjects, the greatest density of CSF-positive extracranial voxels was in the nasal turbinates. Tracer concentration analyses validated the superior nasal turbinate CSF signal intensity. AD patients showed ventricular tracer clearance reduced by 23% and 66% fewer superior turbinate CSF egress sites. Ventricular CSF clearance was inversely associated with amyloid deposition. Conclusion: The human nasal turbinate is part of the CSF clearance system. Lateral ventricle and superior nasal turbinate CSF clearance abnormalities are found in AD. Ventricular CSF clearance reductions are associated with increased brain amyloid depositions. These data suggest that PET-measured CSF clearance is a biomarker of potential interest in AD and other neurodegenerative diseases. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.
Quinoa - Adaptive Computational Fluid Dynamics, 0.2
Energy Technology Data Exchange (ETDEWEB)
2017-09-22
Quinoa is a set of computational tools that enables research and numerical analysis in fluid dynamics. At this time it remains a test-bed to experiment with various algorithms using fully asynchronous runtime systems. Currently, Quinoa consists of the following tools: (1) Walker, a numerical integrator for systems of stochastic differential equations in time. It is a mathematical tool to analyze and design the behavior of stochastic differential equations. It allows the estimation of arbitrary coupled statistics and probability density functions and is currently used for the design of statistical moment approximations for multiple mixing materials in variable-density turbulence. (2) Inciter, an overdecomposition-aware finite element field solver for partial differential equations using 3D unstructured grids. Inciter is used to research asynchronous mesh-based algorithms and to experiment with coupling asynchronous to bulk-synchronous parallel code. Two planned new features of Inciter, compared to the previous release (LA-CC-16-015), to be implemented in 2017, are (a) a simple Navier-Stokes solver for ideal single-material compressible gases, and (b) solution-adaptive mesh refinement (AMR), which enables dynamically concentrating compute resources to regions with interesting physics. Using the NS-AMR problem we plan to explore how to scale such high-load-imbalance simulations, representative of large production multiphysics codes, to very large problems on very large computers using an asynchronous runtime system. (3) RNGTest, a test harness to subject random number generators to stringent statistical tests enabling quantitative ranking with respect to their quality and computational cost. (4) UnitTest, a unit test harness, running hundreds of tests per second, capable of testing serial, synchronous, and asynchronous functions. (5) MeshConv, a mesh file converter that can be used to convert 3D tetrahedron meshes from and to either of the following formats: Gmsh
The Fluid Dynamics of Secondary Cooling Air-Mist Jets
Hernández C., I.; Acosta G., F. A.; Castillejos E., A. H.; Minchaca M., J. I.
2008-10-01
For the conditions of thin-slab continuous casting, air-mist secondary cooling occurs in the transition-boiling regime, possibly as a result of an enhanced intermittent contact of high- momentum water drops with the hot metallic surface. The dynamics of the intermittent contact or wetting/dewetting process should be primarily dependent on the drop size, drop impact-velocity and -angle and water-impact flux, which results from the nozzle design and the interaction of the drops with the conveying and entrained air stream. The aim of this article was to develop a model for predicting the last three parameters based on the design and operating characteristics of air-mist nozzles and on experimentally determined drop-size distributions. To do this, the Eulerian fluid-flow field of the air in three dimensions and steady state and the Lagrangian velocities and trajectories of water drops were computed by solving the turbulent Navier Stokes equation for the air coupled to the motion equation for the water drops. In setting this model, it was particularly important to specify appropriately the air-velocity profile at the nozzle orifice, as well as, the water-flux distribution, and the velocities (magnitude and angle) and exit positions of drops with the different sizes generated, hence special attention was given to these aspects. The computed drop velocities, water-impact flux distributions, and air-mist impact-pressure fields compared well with detailed laboratory measurements carried out at ambient temperature. The results indicate that under practical nozzle-operating conditions, the impinging-droplet Weber numbers are high, over most of the water footprint, suggesting that the droplets should establish an intimate contact with the solid surface. However, the associated high mean-droplet fluxes hint that this contact may be obstructed by drop interference at the surface, which would undermine the heat-extraction effectiveness of the impinging mist. The model also points
A light-scattering study of the nonlinear dynamics of electrorheological fluids in oscillatory shear
International Nuclear Information System (INIS)
Martin, J.E.; Odinek, J.
1995-01-01
We report a real time, two-dimensional light-scattering study of the nonlinear dynamics of field-induced structures in an electrorheological (ER) fluid subjected to oscillatory shear. We have developed a simple kinetic chain model of the observed dynamics by considering the response of a fragmenting/aggregating particle chain to the prevailing hydrodynamic and electrostatic forces. This theory of the dynamics is then used to describe the nonlinear rheology of ER fluids, and it is concluded that light scattering allows one to indirectly probe the stress in an ER fluid. copyright 1995 Society of Rheology
Optics and Fluid Dynamics Department. Annual progress report 1 January - 31 December 1990
International Nuclear Information System (INIS)
Juul Rasmussen, J.; Hanson, S.G.
1991-02-01
Research in the Optics and Fluid Dynamics Department covers plasma physics, fluid dynamics, optics, and neural networks. Plasma physics is concentrated on basic investigations with relevance to fusion plasmas. Both theoretical and experimental work has been performed. Pellet injection systems have been developed. Within the area of fluid dynamics spectral models for studying the dynamcis of coherent structures have been developed. Optical diagnostic methods based on quasi-elastic light scattering have been developed. Beam propagation in random and nonlinear media has been investigated. Spatial and temporal processing schemes, especially for pattern recognition, have been investigated. (author)
International Nuclear Information System (INIS)
Elfelsoufi, Z.; Azrar, L.
2016-01-01
In this paper, a mathematical modeling of flutter and divergence analyses of fluid conveying pipes based on integral equation formulations is presented. Dynamic stability problems related to fluid pressure, velocity, tension, topography slope and viscoelastic supports and foundations are formulated. A methodological approach is presented and the required matrices, associated to the influencing fluid and pipe parameters, are explicitly given. Internal discretizations are used allowing to investigate the deformation, the bending moment, slope and shear force at internal points. Velocity–frequency, pressure-frequency and tension-frequency curves are analyzed for various fluid parameters and internal elastic supports. Critical values of divergence and flutter behaviors with respect to various fluid parameters are investigated. This model is general and allows the study of dynamic stability of tubes crossed by stationary and instationary fluid on various types of supports. Accurate predictions can be obtained and are of particular interest for a better performance and for an optimal safety of piping system installations. - Highlights: • Modeling the flutter and divergence of fluid conveying pipes based on RBF. • Dynamic analysis of a fluid conveying pipe with generalized boundary conditions. • Considered parameters fluid are the pressure, tension, slopes topography, velocity. • Internal support increase the critical velocity value. • This methodologies determine the fluid parameters effects.
Dynamic rheological properties of viscoelastic magnetic fluids in uniform magnetic fields
International Nuclear Information System (INIS)
Yamaguchi, Hiroshi; Niu Xiaodong; Ye Xiaojiang; Li Mingjun; Iwamoto, Yuhiro
2012-01-01
The dynamic rheological properties of viscoelastic magnetic fluids in externally applied uniform magnetic fields are investigated by a laboratory-made cone-plate rheometer in this study. In particular, the effects of the magnetic field on the viscoelastic properties (the complex dynamic modulus) of the viscoelastic magnetic fluids are studied. In the investigation, three viscoelastic magnetic fluids are made by mixing a magnetic fluid and a viscoelastic fluid with different mass ratios. As a supplementation to the experimental investigation, a theoretical analysis is also presented. The present study shows that the viscosity and elasticity of the viscoelastic magnetic fluids are significantly influenced by the magnetic field and the concentrations of the magnetic particles in the test fluids. Theoretical analysis qualitatively explains the present findings. - Highlights: ► The dynamic rheological properties of the viscoelastic magnetic fluids in uniform magnetic fields are investigated. ► Both the magnetic field strength and the concentration of the magnetic particles in the fluids have significant effects on the viscosity and elasticity of the viscoelastic magnetic fluids. ► Theoretical prediction and analysis qualitatively explains the present findings.
Fluid dynamics of the sliding plate | Makinde | Quaestiones ...
African Journals Online (AJOL)
A fluid with viscosity which depends on temperature and concentration is placed between two infinite parallel plates moving relative to each other with constant velocity. On the basis of certain simplifying assumptions, the fluid equations of continuity, momentum, energy and concentration are obtained and solved analytically ...
Stability and dynamics of fluid flow past deformable solid media
Indian Academy of Sciences (India)
Objective of our work: To uncover qualitatively new instabilities in flow past deformable solid media. (Will not consider tube collapse due to external pressure changes.) Page 5. Introduction. 5. Fluid Governing equations. Incompressible; both Newtonian and Viscoelastic fluids. $%' & (. )0&01)243. 5&26(. &08720. Newtonian ...
Global Dynamics of Shaft Lines Rotating in Surrounding Fluids Application to Thin Fluid Films
Directory of Open Access Journals (Sweden)
David Lornage
2004-01-01
a disc and a thin-walled shaft mounted on a hydrodynamic bearing. The second is intended for studying a more realistic structure composed of a shaft and a wheel coupled with a fluid film between the wheel and a casing. These applications make it possible to identify trends related to fluid effects and couplings between the flexible structural parts.
Mapping of polycrystalline films of biological fluids utilizing the Jones-matrix formalism
Ushenko, Vladimir A.; Dubolazov, Alexander V.; Pidkamin, Leonid Y.; Sakchnovsky, Michael Yu; Bodnar, Anna B.; Ushenko, Yuriy A.; Ushenko, Alexander G.; Bykov, Alexander; Meglinski, Igor
2018-02-01
Utilizing a polarized light approach, we reconstruct the spatial distribution of birefringence and optical activity in polycrystalline films of biological fluids. The Jones-matrix formalism is used for an accessible quantitative description of these types of optical anisotropy. We demonstrate that differentiation of polycrystalline films of biological fluids can be performed based on a statistical analysis of the distribution of rotation angles and phase shifts associated with the optical activity and birefringence, respectively. Finally, practical operational characteristics, such as sensitivity, specificity and accuracy of the Jones-matrix reconstruction of optical anisotropy, were identified with special emphasis on biomedical application, specifically for differentiation of bile films taken from healthy donors and from patients with cholelithiasis.
International Nuclear Information System (INIS)
Hussain, M.N.; Benedict, C.R.
1987-01-01
This paper describes several modifications of the original radioenzymatic assay for serotonin which increase the sensitivity of the assay 20-fold as well as enhance its reliability. Using this method serotonin concentrations can be directly measured in biological examples without precleaning the sample. When compared to currently available methods this assay is specific and sensitive to approximately 1 pg of serotonin and can be used to measure serotonin levels in individual brain nuclei or microliter quantities of biological fluids. This assay can be easily adapted for the direct measurement of N-acetylserotonin. A large number of samples can be assayed in a single working day
Analytical, Computational Fluid Dynamics and Flight Dynamics of Coandă MAV
Djojodihardjo, H.; Ahmed, RI
2016-11-01
The paper establishes the basic working relationships among various relevant variables and parameters governing the aerodynamics forces and performance measures of Coandă MAV in hover and translatory motion. With such motivation, capitalizing on the basic fundamental principles, the Fluid Dynamics and Flight Mechanics of semi-spherical Coandă MAV configurations are revisited and analyzed as a baseline. To gain better understanding on the principle of Coandă MAV lift generation, a mathematical model for a spherical Coandă MAV is developed and analyzed from first physical principles. To gain further insight into the prevailing flow field around a Coandă MAV, as well as to verify the theoretical prediction presented in the work, a computational fluid dynamic CFD simulation for a Coandă MAV generic model are elaborated using commercial software FLUENT®. In addition, the equation of motion for translatory motion of Coandă MAV is elaborated. The mathematical model and derived performance measures are shown to be capable in describing the physical phenomena of the flow field of the semi-spherical Coandă MAV. The relationships between the relevant parameters of the mathematical model of the Coandă MAV to the forces acting on it are elaborated subsequently.
Haneef, Jamshed; Shaharyar, Mohammad; Husain, Asif; Rashid, Mohd; Mishra, Ravinesh; Parveen, Shama; Ahmed, Niyaz; Pal, Manoj; Kumar, Deepak
2013-01-01
Liquid chromatography tandem mass chromatography (LCâMS/MS) is an important hyphenated technique for quantitative analysis of drugs in biological fluids. Because of high sensitivity and selectivity, LCâMS/MS has been used for pharmacokinetic studies, metabolites identification in the plasma and urine. This manuscript gives comprehensive analytical review, focusing on chromatographic separation approaches (column packing materials, column length and mobile phase) as well as different acquisiti...
Haneef, Jamshed; Shaharyar, Mohammad; Husain, Asif; Rashid, Mohd; Mishra, Ravinesh; Parveen, Shama; Ahmed, Niyaz; Pal, Manoj; Kumar, Deepak
2013-01-01
Liquid chromatography tandem mass chromatography (LC–MS/MS) is an important hyphenated technique for quantitative analysis of drugs in biological fluids. Because of high sensitivity and selectivity, LC–MS/MS has been used for pharmacokinetic studies, metabolites identification in the plasma and urine. This manuscript gives comprehensive analytical review, focusing on chromatographic separation approaches (column packing materials, column length and mobile phase) as well as different acquisiti...
Isolation and characterization of exosomes from cell culture supernatants and biological fluids
Théry, Clotilde; Amigorena, Sebastian; Raposo, Graça; Clayton, Aled
2006-01-01
Exosomes are small membrane vesicles found in cell culture supernatants and in different biological fluids. Exosomes form in a particular population of endosomes, called multivesicular bodies (MVBs), by inward budding into the lumen of the compartment. Upon fusion of MVBs with the plasma membrane, these internal vesicles are secreted. Exosomes possess a defined set of membrane and cytosolic proteins. The physiological function of exosomes is still a matter of debate, but increasing results in...
An improved mass spectrometry-based measurement of NO metabolites in biological fluids.
Yang, Xingbin; Bondonno, Catherine P; Indrawan, Adeline; Hodgson, Jonathan M; Croft, Kevin D
2013-03-01
Assessment of NO metabolism in vivo relies on the accurate measurement of its metabolites nitrite (NO(2)(-)), nitrate (NO(3)(-)), and nitrosothiols (RSNOs) in biological fluids. We report a sensitive method to simultaneously determine NO(2)(-) and NO(3)(-) in biological matrixes. Tetraoctylammonium was used to catalyze the complete conversion of NO(2)(-) and NO(3)(-) to stable pentafluorobenzyl (PFB) derivatives directly from aqueous acetone medium before gas chromatography and negative-ion chemical ionization mass spectrometry (GC/NICI/MS). This catalyst dramatically improved the yield of PFB derivatives for NO(2)(-) (4.5 times) and NO(3)(-) (55 times) compared to noncatalyzed derivatization methods. Analysis was performed using (15)N-labeled internal standards by selected-ion monitoring at m/z 46 for fragment NO(2)(-) and m/z 47 for its isotope analogue, (15)NO(2)(-), and m/z 62 for NO(3)(-) and m/z 63 for (15)NO(3)(-). This method allowed specific detection of both PFB derivatives over a wide dynamic range with a limit of detection below 4.5 pg for NO(2)(-) and 2.5 pg for NO(3)(-). After the specific conversion of RSNOs by HgCl(2) to NO(2)(-), this GC/NICI/MS analysis was used to measure RSNOs in plasma. A further comparison with the widely used tri-iodide chemiluminescence (I(3)(-)-CL) assay indicated that the GC/MS assay validated the lower physiological RSNO and nitrite levels reported using I(3)(-)-CL detection compared with values obtained using UV-photolysis methods. Plasma levels of RSNOs determined by GC/MS and I(3)(-)-CL were well correlated (r = 0.8). The improved GC/MS method was successfully used to determine the changes in plasma, urinary, and salivary NO(2)(-) and NO(3)(-) as well as plasma RSNOs in humans after either a low-NO(3)(-) or a high-NO(3)(-) meal. Copyright © 2012 Elsevier Inc. All rights reserved.
Chemical and biological activity in open flows: A dynamical system approach
International Nuclear Information System (INIS)
Tel, Tamas; Moura, Alessandro de; Grebogi, Celso; Karolyi, Gyoergy
2005-01-01
Chemical and biological processes often take place in fluid flows. Many of them, like environmental or microfluidical ones, generate filamentary patterns which have a fractal structure, due to the presence of chaos in the underlying advection dynamics. In such cases, hydrodynamical stirring strongly couples to the reactivity of the advected species: the outcome of the reaction is then typically different from that of the same reaction taking place in a well-mixed environment. Here we review recent progress in this field, which became possible due to the application of methods taken from dynamical system theory. We place special emphasis on the derivation of effective rate equations which contain singular terms expressing the fact that the reaction takes place on a moving fractal catalyst, on the unstable foliation of the reaction free advection dynamics
Palacios, Angel Fierros
2006-01-01
The book describes Fluid Dynamics, Magnetohydrodynamics, and Classical Thermodynamics as branches of Lagrange’s Analytical Mechanics; and in that sense, the approach presented in it is markedly different from the treatment given to them in traditional text books. A Hamilton-Type Variational Principle as the proper mathematical technique for the theoretical description of the dynamic state of any fluid is formulated. The scheme is completed proposing a new group of variations regarding the evolution parameter which is time; and with the demonstration of a theorem concerning the invariance of the action integral under continuous and infinitesimal temporary transformations. A general methodology for the mathematical treatment of fluid flows characteristic of Fluid Dynamics, Magnetohydrodynamics, and also fluids at rest proper of Classical Thermodynamics is presented. The volume contains the most significant results obtained by the author in Continuous Mechanics and Astrophysics.
Activating and inhibiting connections in biological network dynamics
Directory of Open Access Journals (Sweden)
Knight Rob
2008-12-01
Full Text Available Abstract Background Many studies of biochemical networks have analyzed network topology. Such work has suggested that specific types of network wiring may increase network robustness and therefore confer a selective advantage. However, knowledge of network topology does not allow one to predict network dynamical behavior – for example, whether deleting a protein from a signaling network would maintain the network's dynamical behavior, or induce oscillations or chaos. Results Here we report that the balance between activating and inhibiting connections is important in determining whether network dynamics reach steady state or oscillate. We use a simple dynamical model of a network of interacting genes or proteins. Using the model, we study random networks, networks selected for robust dynamics, and examples of biological network topologies. The fraction of activating connections influences whether the network dynamics reach steady state or oscillate. Conclusion The activating fraction may predispose a network to oscillate or reach steady state, and neutral evolution or selection of this parameter may affect the behavior of biological networks. This principle may unify the dynamics of a wide range of cellular networks. Reviewers Reviewed by Sergei Maslov, Eugene Koonin, and Yu (Brandon Xia (nominated by Mark Gerstein. For the full reviews, please go to the Reviewers' comments section.
Mechanisms and models of the dehydration self-organization in biological fluids
International Nuclear Information System (INIS)
Tarasevich, Yurii Yu
2004-01-01
The dehydration self-organization phenomenon in biological fluids attracted the attention of researchers slightly more than a decade ago. While seemingly simple (the structure formation is possible to observe even in domestic conditions), the effect turned out to be extremely complicated and to involve a number of interrelated processes of a different physical nature. The dehydration self-organization effect in biological fluids underlies a medical diagnostic technique patented in 40 countries of the world, while the mechanisms that underlie the technique still remain largely obscure. This review is an attempt to draw an integrated picture of the current state of the problem: to emphasize reliably established facts and the problems that remain to be solved, to put an end to speculation, and to characterize the available theories and models. An analysis of the literature sources allows us to draw the conclusion that the effects observed in the dehydration of biological fluids are typical for colloidal solutions in general and can be described in the framework of conventional physical approaches. (from the current literature)
Dynamics of two coaxial cylindrical shells containing viscous fluid
International Nuclear Information System (INIS)
Yeh, T.T.; Chen, S.S.
1976-09-01
This study was motivated by the need to design the thermal shield in reactor internals and other system components to avoid detrimental flow-induced vibrations. The system component is modeled as two coaxial shells separated by a viscous fluid. In the analysis, Flugge's shell equations of motion and linearized Navier-Stokes equation for viscous fluid are employed. First, a traveling-wave type solution is taken for shells and fluid. Then, from the interface conditions between the shells and fluid, the solution for the fluid medium is expressed in terms of shell displacements. Finally, using the shell equations of motion gives the frequency equation, from which the natural frequency, mode shape, and modal damping ratio of coupled modes can be calculated. The analytical results show a fairly good qualitative agreement with the published experimental data. Some important conclusions are as follows: (1) In computing the natural frequencies and mode shapes of uncoupled modes and coupled modes, the fluid may be considered inviscid and incompressible. (2) There exists out-of-phase and in-phase modes. The lowest natural frequency is always associated with the out-of-phase mode. (3) The lowest natural frequency of coupled modes is lower than the uncoupled modes. (4) The fluid viscosity contributes significantly to damping, in particular, the modal damping of the out-of-phase modes isrelatively large for small gaps. (5) If the fluid gap is small, or the fluid viscosity is relatively high, the simulation of the vibration Reynolds number should be included to ensure that modal damping of the model is properly accounted for. With the presented analysis and results, the frequency and damping characteristics can be analyzed and design parameters can be related to frequency and damping
A Modelling Approach to Multibody Dynamics of Fluid Power Machinery with Hydrodynamic Lubrication
DEFF Research Database (Denmark)
Johansen, Per; Rømer, Daniel; Andersen, Torben Ole
2013-01-01
The efficiency potential of the digital displacement technology and the increasing interest in hydraulic transmissions in wind and wave energy applications has created an incentive for development of high efficiency fluid power machinery. Modelling and analysis of fluid power machinery loss...... to be coupled with multibody dynamics models. The focus of the current paper is an approach where the transient pressure field in hydrodynamic lubricated joint clearances are modelled by a set of control volumes and coupled with the fluid power machinery mechanics....
Dynamics of Biomembranes: Effect of the Bulk Fluid
Bonito, A.
2011-01-01
We derive a biomembrane model consisting of a fluid enclosed by a lipid membrane. The membrane is characterized by its Canham-Helfrich energy (Willmore energy with area constraint) and acts as a boundary force on the Navier-Stokes system modeling an incompressible fluid. We give a concise description of the model and of the associated numerical scheme. We provide numerical simulations with emphasis on the comparisons between different types of flow: the geometric model which does not take into account the bulk fluid and the biomembrane model for two different regimes of parameters. © EDP Sciences, 2011.
Many-body dissipative particle dynamics modeling of fluid flow in fine-grained nanoporous shales
Xia, Yidong; Goral, Jan; Huang, Hai; Miskovic, Ilija; Meakin, Paul; Deo, Milind
2017-05-01
A many-body dissipative particle dynamics model, namely, MDPD, is applied for simulation of pore-scale, multi-component, multi-phase fluid flows in fine-grained, nanoporous shales. Since this model is able to simultaneously capture the discrete features of fluid molecules in nanometer size pores and continuum fluid dynamics in larger pores, and is relatively easy to parameterize, it has been recognized as being particularly suitable for simulating complex fluid flow in multi-length-scale nanopore networks of shales. A remarkable feature of this work is the integration of a high-resolution FIB-SEM (focused ion beam scanning electron microscopy) digital imaging technique to the MDPD model for providing 3D voxel data that contain the invaluable geometrical and compositional information of shale samples. This is the first time that FIB-SEM is seamlessly linked to a Lagrangian model like MDPD for fluid flow simulation, which offers a robust approach to bridging gaps between the molecular- and continuum-scales, since the relevant spatial and temporal scales are too big for molecular dynamics, and too small for computational fluid dynamics with known constitutive models. Simulations ranging from a number of benchmark problems to a forced two-fluid flow in a Woodford shale sample are presented. Results indicate that this model can be used to deliver reasonable simulations for multi-component, multi-phase fluid flows in arbitrarily complex pore networks in shales.
Dynamic Analysis of Fluid Power Drive-trains for Variable Speed Wind Turbines : A Parameter Study
Jarquin Laguna, A.; Diepeveen, N.F.B.
2013-01-01
In the pursuit of making wind energy technology more economically attractive, the application of fluid power technology for the transmission of wind energy is being developed by several parties all over the world. This paper presents a dynamic model of a fluid power transmission for variable speed
National Research Council Canada - National Science Library
Hisley, Dixie
1999-01-01
.... The goals of this report are: (1) to investigate the performance of message passing and loop level parallelization techniques, as they were implemented in the computational fluid dynamics (CFD...
Computational Fluid Dynamic (CFD) Analysis of a Generic Missile With Grid Fins
National Research Council Canada - National Science Library
DeSpirito, James
2000-01-01
This report presents the results of a study demonstrating an approach for using viscous computational fluid dynamic simulations to calculate the flow field and aerodynamic coefficients for a missile with grid fin...
Terzic, Jenny; Nagarajah, Romesh; Alamgir, Muhammad
2013-01-01
Accurate fluid level measurement in dynamic environments can be assessed using a Support Vector Machine (SVM) approach. SVM is a supervised learning model that analyzes and recognizes patterns. It is a signal classification technique which has far greater accuracy than conventional signal averaging methods. Ultrasonic Fluid Quantity Measurement in Dynamic Vehicular Applications: A Support Vector Machine Approach describes the research and development of a fluid level measurement system for dynamic environments. The measurement system is based on a single ultrasonic sensor. A Support Vector Machines (SVM) based signal characterization and processing system has been developed to compensate for the effects of slosh and temperature variation in fluid level measurement systems used in dynamic environments including automotive applications. It has been demonstrated that a simple ν-SVM model with Radial Basis Function (RBF) Kernel with the inclusion of a Moving Median filter could be used to achieve the high levels...
Riemann solvers and numerical methods for fluid dynamics a practical introduction
Toro, Eleuterio F
2009-01-01
High resolution upwind and centred methods are a mature generation of computational techniques applicable to a range of disciplines, Computational Fluid Dynamics being the most prominent. This book gives a practical presentation of this class of techniques.
This paper discusses the status and application of Computational Fluid Dynamics (CFD) models to address challenges for modeling human exposures to air pollutants around urban building microenvironments. There are challenges for more detailed understanding of air pollutant sour...
A FRAMEWORK FOR FINE-SCALE COMPUTATIONAL FLUID DYNAMICS AIR QUALITY MODELING AND ANALYSIS
Fine-scale Computational Fluid Dynamics (CFD) simulation of pollutant concentrations within roadway and building microenvironments is feasible using high performance computing. Unlike currently used regulatory air quality models, fine-scale CFD simulations are able to account rig...
National Aeronautics and Space Administration — Computational fluid dynamics (CFD) simulations are routinely used by NASA to optimize the design of propulsion systems. Current methods for CFD modeling rely on...
Application of Computational Fluid Dynamics (CFD) modelling to retail display and storage of food
Foster, A; Evans, J; James, SJ
2006-01-01
This paper describes the work that has been conducted at the University of Bristol on the use of computational fluid dynamic (CFD) modelling to aid the design of retail display cabinets and storage rooms.
Computational fluid dynamics analysis of aerosol deposition in pebble beds
Mkhosi, Margaret Msongi
2007-12-01
The Pebble Bed Modular Reactor is a high temperature gas cooled reactor which uses helium gas as a coolant. The reactor uses spherical graphite pebbles as fuel. The fuel design is inherently resistant to the release of the radioactive material up to high temperatures; therefore, the plant can withstand a broad spectrum of accidents with limited release of radionuclides to the environment. Despite safety features of the concepts, these reactors still contain large inventories of radioactive materials. The transport of most of the radioactive materials in an accident occurs in the form of aerosol particles. In this dissertation, the limits of applicability of existing computational fluid dynamics code FLUENT to the prediction of aerosol transport have been explored. The code was run using the Reynolds Averaged Navier-Stokes turbulence models to determine the effects of different turbulence models on the prediction of aerosol particle deposition. Analyses were performed for up to three unit cells in the orthorhombic configuration. For low flow conditions representing natural circulation driven flow, the laminar flow model was used and the results were compared with existing experimental data for packed beds. The results compares well with experimental data in the low flow regime. For conditions corresponding to normal operating of the reactor, analyses were performed using the standard k-ɛ turbulence model. From the inertial deposition results, a correlation that can be used to estimate the deposition of aerosol particles within pebble beds given inlet flow conditions has been developed. These results were converted into a dimensionless form as a function of a modified Stokes number. Based on results obtained in the laminar regime and for individual pebbles, the correlation developed for the inertial impaction component of deposition is believed to be credible. The form of the correlation developed also allows these results to be applied to pebble beds of different
Computational Fluid Dynamics Simulation of Dual Bell Nozzle Film Cooling
Braman, Kalen; Garcia, Christian; Ruf, Joseph; Bui, Trong
2015-01-01
Marshall Space Flight Center (MSFC) and Armstrong Flight Research Center (AFRC) are working together to advance the technology readiness level (TRL) of the dual bell nozzle concept. Dual bell nozzles are a form of altitude compensating nozzle that consists of two connecting bell contours. At low altitude the nozzle flows fully in the first, relatively lower area ratio, nozzle. The nozzle flow separates from the wall at the inflection point which joins the two bell contours. This relatively low expansion results in higher nozzle efficiency during the low altitude portion of the launch. As ambient pressure decreases with increasing altitude, the nozzle flow will expand to fill the relatively large area ratio second nozzle. The larger area ratio of the second bell enables higher Isp during the high altitude and vacuum portions of the launch. Despite a long history of theoretical consideration and promise towards improving rocket performance, dual bell nozzles have yet to be developed for practical use and have seen only limited testing. One barrier to use of dual bell nozzles is the lack of control over the nozzle flow transition from the first bell to the second bell during operation. A method that this team is pursuing to enhance the controllability of the nozzle flow transition is manipulation of the film coolant that is injected near the inflection between the two bell contours. Computational fluid dynamics (CFD) analysis is being run to assess the degree of control over nozzle flow transition generated via manipulation of the film injection. A cold flow dual bell nozzle, without film coolant, was tested over a range of simulated altitudes in 2004 in MSFC's nozzle test facility. Both NASA centers have performed a series of simulations of that dual bell to validate their computational models. Those CFD results are compared to the experimental results within this paper. MSFC then proceeded to add film injection to the CFD grid of the dual bell nozzle. A series of
Cerebrospinal fluid clearance in Alzheimer disease measured with dynamic PET
DEFF Research Database (Denmark)
De Leon, Mony J.; Li, Yi; Okamura, Nobuyuki
2017-01-01
Evidence supporting the hypothesis that reduced cerebrospinal fluid (CSF) clearance is involved in the pathophysiology of Alzheimer disease (AD) comes primarily from rodent models. However, unlike rodents, in which predominant extracranial CSF egress is via olfactory nerves traversing the cribrif......Evidence supporting the hypothesis that reduced cerebrospinal fluid (CSF) clearance is involved in the pathophysiology of Alzheimer disease (AD) comes primarily from rodent models. However, unlike rodents, in which predominant extracranial CSF egress is via olfactory nerves traversing...
International Nuclear Information System (INIS)
Melo, Ana Cristina Bezerra Azedo de
2004-12-01
The fluid dynamic behavior of a riser in a cold type FCC model was investigated by means of catalyst concentration distribution measured with gamma attenuation and simulated with a mathematical model. In the riser of the cold model, MEF, 0,032 m in diameter, 2,30 m in length the fluidized bed, whose components are air and FCC catalyst, circulates. The MEF is operated by automatic control and instruments for measuring fluid dynamic variables. An axial catalyst concentration distribution was measured using an Am-241 gamma source and a NaI detector coupled to a multichannel provided with a software for data acquisition and evaluation. The MEF was adapted for a fluid dynamic model validation which describes the flow in the riser, for example, by introducing an injector for controlling the solid flow in circulation. Mathematical models were selected from literature, analyzed and tested to simulate the fluid dynamic of the riser. A methodology for validating fluid dynamic models was studied and implemented. The stages of the work were developed according to the validation methodology, such as data planning experiments, study of the equations which describe the fluidodynamic, computational solvers application and comparison with experimental data. Operational sequences were carried out keeping the MEF conditions for measuring catalyst concentration and simultaneously measuring the fluid dynamic variables, velocity of the components and pressure drop in the riser. Following this, simulated and experimental values were compared and statistical data treatment done, aiming at the required precision to validate the fluid dynamic model. The comparison tests between experimental and simulated data were carried out under validation criteria. The fluid dynamic behavior of the riser was analyzed and the results and the agreement with literature were discussed. The adopt model was validated under the MEF operational conditions, for a 3 to 6 m/s gas velocity in the riser and a slip
Comparison of supercomputers and mini-supercomputers for computational fluid dynamics calculations
International Nuclear Information System (INIS)
Gentzsch, W.
1988-01-01
Computational fluid dynamics (CFD) is a powerful tool for the simulation of complex fluid dynamics problems. In the future, the progress in CFD will depend on efficient algorithms as well as on the power and storage capacity of the computers available. A careful study and comparison of these supercomputers, therefore, is necessary. The following paper presents a short description of the Engineering and Scientific Model Benchmark, the supercomputers and mini-supercomputers under consideration, and a discussion of the benchmark results
He, Tao; Zhang, Hexin; Zhang, Kai
2018-01-01
In this paper the cell-based smoothed finite element method (CS-FEM) is introduced into two mainstream aspects of computational fluid dynamics: incompressible flows and fluid-structure interaction (FSI). The emphasis is placed on the fluid gradient smoothing which simply requires equal numbers of Gaussian points and smoothing cells in each four-node quadrilateral element. The second-order, smoothed characteristic-based split scheme in conjunction with a pressure stabilization is then presented to settle the incompressible Navier-Stokes equations. As for FSI, CS-FEM is applied to the geometrically nonlinear solid as usual. Following an efficient mesh deformation strategy, block-Gauss-Seidel procedure is adopted to couple all individual fields under the arbitrary Lagriangian-Eulerian description. The proposed solvers are carefully validated against the previously published data for several benchmarks, revealing visible improvements in computed results.
Bions: A Family of Biomimetic Mineralo-Organic Complexes Derived from Biological Fluids
Martel, Jan; Young, John D.
2013-01-01
Mineralo-organic nanoparticles form spontaneously in human body fluids when the concentrations of calcium and phosphate ions exceed saturation. We have shown previously that these mineralo-organic nanoparticles possess biomimetic properties and can reproduce the whole phenomenology of the so-called nanobacteria—mineralized entities initially described as the smallest microorganisms on earth. Here, we examine the possibility that various charged elements and ions may form mineral nanoparticles with similar properties in biological fluids. Remarkably, all the elements tested, including sodium, magnesium, aluminum, calcium, manganese, iron, cobalt, nickel, copper, zinc, strontium, and barium form mineralo-organic particles with bacteria-like morphologies and other complex shapes following precipitation with phosphate in body fluids. Upon formation, these mineralo-organic particles, which we term bions, invariably accumulate carbonate apatite during incubation in biological fluids; yet, the particles also incorporate additional elements and thus reflect the ionic milieu in which they form. Bions initially harbor an amorphous mineral phase that gradually converts to crystals in culture. Our results show that serum produces a dual inhibition-seeding effect on bion formation. Using a comprehensive proteomic analysis, we identify a wide range of proteins that bind to these mineral particles during incubation in medium containing serum. The two main binding proteins identified, albumin and fetuin-A, act as both inhibitors and seeders of bions in culture. Notably, bions possess several biomimetic properties, including the possibility to increase in size and number and to be sub-cultured in fresh culture medium. Based on these results, we propose that bions represent biological, mineralo-organic particles that may form in the body under both physiological and pathological homeostasis conditions. These mineralo-organic particles may be part of a physiological cycle that
Bions: a family of biomimetic mineralo-organic complexes derived from biological fluids.
Directory of Open Access Journals (Sweden)
Cheng-Yeu Wu
Full Text Available Mineralo-organic nanoparticles form spontaneously in human body fluids when the concentrations of calcium and phosphate ions exceed saturation. We have shown previously that these mineralo-organic nanoparticles possess biomimetic properties and can reproduce the whole phenomenology of the so-called nanobacteria-mineralized entities initially described as the smallest microorganisms on earth. Here, we examine the possibility that various charged elements and ions may form mineral nanoparticles with similar properties in biological fluids. Remarkably, all the elements tested, including sodium, magnesium, aluminum, calcium, manganese, iron, cobalt, nickel, copper, zinc, strontium, and barium form mineralo-organic particles with bacteria-like morphologies and other complex shapes following precipitation with phosphate in body fluids. Upon formation, these mineralo-organic particles, which we term bions, invariably accumulate carbonate apatite during incubation in biological fluids; yet, the particles also incorporate additional elements and thus reflect the ionic milieu in which they form. Bions initially harbor an amorphous mineral phase that gradually converts to crystals in culture. Our results show that serum produces a dual inhibition-seeding effect on bion formation. Using a comprehensive proteomic analysis, we identify a wide range of proteins that bind to these mineral particles during incubation in medium containing serum. The two main binding proteins identified, albumin and fetuin-A, act as both inhibitors and seeders of bions in culture. Notably, bions possess several biomimetic properties, including the possibility to increase in size and number and to be sub-cultured in fresh culture medium. Based on these results, we propose that bions represent biological, mineralo-organic particles that may form in the body under both physiological and pathological homeostasis conditions. These mineralo-organic particles may be part of a
Bions: a family of biomimetic mineralo-organic complexes derived from biological fluids.
Wu, Cheng-Yeu; Young, Lena; Young, David; Martel, Jan; Young, John D
2013-01-01
Mineralo-organic nanoparticles form spontaneously in human body fluids when the concentrations of calcium and phosphate ions exceed saturation. We have shown previously that these mineralo-organic nanoparticles possess biomimetic properties and can reproduce the whole phenomenology of the so-called nanobacteria-mineralized entities initially described as the smallest microorganisms on earth. Here, we examine the possibility that various charged elements and ions may form mineral nanoparticles with similar properties in biological fluids. Remarkably, all the elements tested, including sodium, magnesium, aluminum, calcium, manganese, iron, cobalt, nickel, copper, zinc, strontium, and barium form mineralo-organic particles with bacteria-like morphologies and other complex shapes following precipitation with phosphate in body fluids. Upon formation, these mineralo-organic particles, which we term bions, invariably accumulate carbonate apatite during incubation in biological fluids; yet, the particles also incorporate additional elements and thus reflect the ionic milieu in which they form. Bions initially harbor an amorphous mineral phase that gradually converts to crystals in culture. Our results show that serum produces a dual inhibition-seeding effect on bion formation. Using a comprehensive proteomic analysis, we identify a wide range of proteins that bind to these mineral particles during incubation in medium containing serum. The two main binding proteins identified, albumin and fetuin-A, act as both inhibitors and seeders of bions in culture. Notably, bions possess several biomimetic properties, including the possibility to increase in size and number and to be sub-cultured in fresh culture medium. Based on these results, we propose that bions represent biological, mineralo-organic particles that may form in the body under both physiological and pathological homeostasis conditions. These mineralo-organic particles may be part of a physiological cycle that
Self-Organized Biological Dynamics and Nonlinear Control
Walleczek, Jan
2006-04-01
The frontiers and challenges of biodynamics research Jan Walleczek; Part I. Nonlinear Dynamics in Biology and Response to Stimuli: 1. External signals and internal oscillation dynamics - principal aspects and response of stimulated rhythmic processes Friedemann Kaiser; 2. Nonlinear dynamics in biochemical and biophysical systems: from enzyme kinetics to epilepsy Raima Larter, Robert Worth and Brent Speelman; 3. Fractal mechanisms in neural control: human heartbeat and gait dynamics in health and disease Chung-Kang Peng, Jeffrey M. Hausdorff and Ary L. Goldberger; 4. Self-organising dynamics in human coordination and perception Mingzhou Ding, Yanqing Chen, J. A. Scott Kelso and Betty Tuller; 5. Signal processing in biochemical reaction networks Adam P. Arkin; Part II. Nonlinear Sensitivity of Biological Systems to Electromagnetic Stimuli: 6. Electrical signal detection and noise in systems with long-range coherence Paul C. Gailey; 7. Oscillatory signals in migrating neutrophils: effects of time-varying chemical and electrical fields Howard R. Petty; 8. Enzyme kinetics and nonlinear biochemical amplification in response to static and oscillating magnetic fields Jan Walleczek and Clemens F. Eichwald; 9. Magnetic field sensitivity in the hippocampus Stefan Engström, Suzanne Bawin and W. Ross Adey; Part III. Stochastic Noise-Induced Dynamics and Transport in Biological Systems: 10. Stochastic resonance: looking forward Frank Moss; 11. Stochastic resonance and small-amplitude signal transduction in voltage-gated ion channels Sergey M. Bezrukov and Igor Vodyanoy; 12. Ratchets, rectifiers and demons: the constructive role of noise in free energy and signal transduction R. Dean Astumian; 13. Cellular transduction of periodic and stochastic energy signals by electroconformational coupling Tian Y. Tsong; Part IV. Nonlinear Control of Biological and Other Excitable Systems: 14. Controlling chaos in dynamical systems Kenneth Showalter; 15. Electromagnetic fields and biological
Rocchitta, Gaia; Spanu, Angela; Babudieri, Sergio; Latte, Gavinella; Madeddu, Giordano; Galleri, Grazia; Nuvoli, Susanna; Bagella, Paola; Demartis, Maria Ilaria; Fiore, Vito; Manetti, Roberto; Serra, Pier Andrea
2016-01-01
Enzyme-based chemical biosensors are based on biological recognition. In order to operate, the enzymes must be available to catalyze a specific biochemical reaction and be stable under the normal operating conditions of the biosensor. Design of biosensors is based on knowledge about the target analyte, as well as the complexity of the matrix in which the analyte has to be quantified. This article reviews the problems resulting from the interaction of enzyme-based amperometric biosensors with complex biological matrices containing the target analyte(s). One of the most challenging disadvantages of amperometric enzyme-based biosensor detection is signal reduction from fouling agents and interference from chemicals present in the sample matrix. This article, therefore, investigates the principles of functioning of enzymatic biosensors, their analytical performance over time and the strategies used to optimize their performance. Moreover, the composition of biological fluids as a function of their interaction with biosensing will be presented. PMID:27249001
Sesti, Erika L.; Alaniva, Nicholas; Rand, Peter W.; Choi, Eric J.; Albert, Brice J.; Saliba, Edward P.; Scott, Faith J.; Barnes, Alexander B.
2018-01-01
We report magic angle spinning (MAS) up to 8.5 kHz with a sample temperature below 6 K using liquid helium as a variable temperature fluid. Cross polarization 13C NMR spectra exhibit exquisite sensitivity with a single transient. Remarkably, 1H saturation recovery experiments show a 1H T1 of 21 s with MAS below 6 K in the presence of trityl radicals in a glassy matrix. Leveraging the thermal spin polarization available at 4.2 K versus 298 K should result in 71 times higher signal intensity. Taking the 1H longitudinal relaxation into account, signal averaging times are therefore predicted to be expedited by a factor of >500. Computer assisted design (CAD) and finite element analysis were employed in both the design and diagnostic stages of this cryogenic MAS technology development. Computational fluid dynamics (CFD) models describing temperature gradients and fluid flow are presented. The CFD models bearing and drive gas maintained at 100 K, while a colder helium variable temperature fluid stream cools the center of a zirconia rotor. Results from the CFD were used to optimize the helium exhaust path and determine the sample temperature. This novel cryogenic experimental platform will be integrated with pulsed dynamic nuclear polarization and electron decoupling to interrogate biomolecular structure within intact human cells.
Directory of Open Access Journals (Sweden)
Aron J. P Andrade
1989-12-01
Full Text Available O comportamento fluidodinâmico e a vida útil média de uma prótese valvular cardíaca são características muito importantes na escolha do modelo de prótese a ser implantada em um determinado paciente. Por esse motivo, foi realizado um estudo comparativo entre as válvulas biológicas de perfil alto e baixo, para se verificarem possíveis alterações na vida média, gradiente de pressão e refluxo, causadas pela diminuição do perfil dessas próteses. Com o auxílio de um duplicador de pulso, foram analisadas cinco próteses de perfil alto e cinco de perfil baixo, todas tamanho 29, fabricadas no Instituto Dante Pazzanese de Cardiologia (IDPC. Mantendo-se a freqüência de batimentos em 100 bpm e a diferença de pressão em 1000 mmHg, verificou-se que a vida útil média da válvula de perfil baixo permaneceu equivalente à de perfil alto. Em outro equipamento, denominado simulador cardíaco, as próteses foram submetidas a condições semelhantes às condições fisiológicas de funcionamento para uma freqüência cardíaca de 75 bpm. Os resultados mostraram que o volume de retorno necessário para fechamento (refluxo, nas válvulas de perfil baixo, é menor do que nas de perfil alto. Isso traz um melhor aproveitamento do efeito de bombeamento do coração. As perdas de carga das válvulas foram comparadas através dos gradientes máximos de pressão visibilizados com a sobreposição dos sinais de pressão. Observou-se que as válvulas de perfil baixo oferecem menos resistência ao fluxo; assim, quando são implantadas, possibilitam uma passagem mais livre e desobstruída do sangue.The fluid dynamic performance and lifetime of a prosthetic heart valve are one of the most important characteristics to determine the choice of what prosthesis must be applied to a patient. Because of this, two different biological prosthetic heart valves profiles (one high profile and other low profile were studied, to verify possible alterations of working
Grain scale observations of stick-slip dynamics in fluid saturated granular fault gouge
Johnson, P. A.; Dorostkar, O.; Guyer, R. A.; Marone, C.; Carmeliet, J.
2017-12-01
We are studying granular mechanics during slip. In the present work, we conduct coupled computational fluid dynamics (CFD) and discrete element method (DEM) simulations to study grain scale characteristics of slip instabilities in fluid saturated granular fault gouge. The granular sample is confined with constant normal load (10 MPa), and sheared with constant velocity (0.6 mm/s). This loading configuration is chosen to promote stick-slip dynamics, based on a phase-space study. Fluid is introduced in the beginning of stick phase and characteristics of slip events i.e. macroscopic friction coefficient, kinetic energy and layer thickness are monitored. At the grain scale, we monitor particle coordination number, fluid-particle interaction forces as well as particle and fluid kinetic energy. Our observations show that presence of fluids in a drained granular fault gouge stabilizes the layer in the stick phase and increases the recurrence time. In saturated model, we observe that average particle coordination number reaches higher values compared to dry granular gouge. Upon slip, we observe that a larger portion of the granular sample is mobilized in saturated gouge compared to dry system. We also observe that regions with high particle kinetic energy are correlated with zones of high fluid motion. Our observations highlight that spatiotemporal profile of fluid dynamic pressure affects the characteristics of slip instabilities, increasing macroscopic friction coefficient drop, kinetic energy release and granular layer compaction. We show that numerical simulations help characterize the micromechanics of fault mechanics.
Influence of biological fluids in bacterial viability on different hospital surfaces and fomites.
Esteves, Deigilam C; Pereira, Valeria C; Souza, Joyce M; Keller, Rogéria; Simões, Rebeca D; Winkelstroter Eller, Lizziane K; Rodrigues, Marcus Vinicius P
2016-03-01
The hospital environment is susceptible to bacterial contamination along with survival in fomites and surfaces, allowing dissemination of potential pathogenic strains. The present research aimed to evaluate the influence of biological fluids in bacterial viability on fomites and surfaces commonly present in nosocomial environment. Four different fomites and surfaces (ceramic floor, cotton fabric fragments and synthetic fibers, and eggcrate foam mattress) were contaminated with potential pathogens (Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa, and Klebsiella pneumoniae), then submitted to influence of biological fluids (blood, urine, artificial saliva). The viability of strains was evaluated at 24 hours after contamination and then in intervals of 7 days, by the colony-forming unit count technique. S aureus presented viability (>70 days) in all conditions tested, E faecalis and K pneumoniae had decreased viability over time, and E coli did not exhibit a growth relationship with surfaces or fluids. Persistence and adaptability capacity of potential pathogens in fomites and surfaces exposed to the patient are important for guidance, planning, and outlining of protocols for microorganism dissemination control and prevention in the health care environment. Copyright © 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
Modeling dynamics of biological and chemical components of aquatic ecosystems
International Nuclear Information System (INIS)
Lassiter, R.R.
1975-05-01
To provide capability to model aquatic ecosystems or their subsystems as needed for particular research goals, a modeling strategy was developed. Submodels of several processes common to aquatic ecosystems were developed or adapted from previously existing ones. Included are submodels for photosynthesis as a function of light and depth, biological growth rates as a function of temperature, dynamic chemical equilibrium, feeding and growth, and various types of losses to biological populations. These submodels may be used as modules in the construction of models of subsystems or ecosystems. A preliminary model for the nitrogen cycle subsystem was developed using the modeling strategy and applicable submodels. (U.S.)
Knotted solutions for linear and nonlinear theories: Electromagnetism and fluid dynamics
Directory of Open Access Journals (Sweden)
Daniel W.F. Alves
2017-10-01
Full Text Available We examine knotted solutions, the most simple of which is the “Hopfion”, from the point of view of relations between electromagnetism and ideal fluid dynamics. A map between fluid dynamics and electromagnetism works for initial conditions or for linear perturbations, allowing us to find new knotted fluid solutions. Knotted solutions are also found to be solutions of nonlinear generalizations of electromagnetism, and of quantum-corrected actions for electromagnetism coupled to other modes. For null configurations, electromagnetism can be described as a null pressureless fluid, for which we can find solutions from the knotted solutions of electromagnetism. We also map them to solutions of Euler's equations, obtained from a type of nonrelativistic reduction of the relativistic fluid equations.
Knotted solutions for linear and nonlinear theories: Electromagnetism and fluid dynamics
Alves, Daniel W. F.; Hoyos, Carlos; Nastase, Horatiu; Sonnenschein, Jacob
2017-10-01
We examine knotted solutions, the most simple of which is the ;Hopfion;, from the point of view of relations between electromagnetism and ideal fluid dynamics. A map between fluid dynamics and electromagnetism works for initial conditions or for linear perturbations, allowing us to find new knotted fluid solutions. Knotted solutions are also found to be solutions of nonlinear generalizations of electromagnetism, and of quantum-corrected actions for electromagnetism coupled to other modes. For null configurations, electromagnetism can be described as a null pressureless fluid, for which we can find solutions from the knotted solutions of electromagnetism. We also map them to solutions of Euler's equations, obtained from a type of nonrelativistic reduction of the relativistic fluid equations.
Symmetry breaking in fluid dynamics: Lie group reducible motions for real fluids
International Nuclear Information System (INIS)
Holm, D.D.
1976-07-01
The physics of fluids is based on certain kinematical invariance principles, which refer to coordinate systems, dimensions, and Galilean reference frames. Other, thermodynamic, symmetry principles are introduced by the material description. In the present work, the interplay between these two kinds of invariance principles is used to solve for classes of one-dimensional non-steady isentropic motions of a fluid whose equation of state is of Mie-Gruneisen type. Also, the change in profile and attenuation of weak shock waves in a dissipative medium is studied at the level of Burgers' approximation from the viewpoint of its underlying symmetry structure. The mathematical method of approach is based on the theory of infinitesimal Lie groups. Fluid motions are characterized according to inequivalent subgroups of the full invariance group of the flow description and exact group reducible solutions are presented
Symmetry breaking in fluid dynamics: Lie group reducible motions for real fluids
Energy Technology Data Exchange (ETDEWEB)
Holm, D.D.
1976-07-01
The physics of fluids is based on certain kinematical invariance principles, which refer to coordinate systems, dimensions, and Galilean reference frames. Other, thermodynamic, symmetry principles are introduced by the material description. In the present work, the interplay between these two kinds of invariance principles is used to solve for classes of one-dimensional non-steady isentropic motions of a fluid whose equation of state is of Mie-Gruneisen type. Also, the change in profile and attenuation of weak shock waves in a dissipative medium is studied at the level of Burgers' approximation from the viewpoint of its underlying symmetry structure. The mathematical method of approach is based on the theory of infinitesimal Lie groups. Fluid motions are characterized according to inequivalent subgroups of the full invariance group of the flow description and exact group reducible solutions are presented.
Littleton, Helen X; Daigger, Glen T; Strom, Peter F
2007-06-01
A full-scale, closed-loop bioreactor (Orbal oxidation ditch, Envirex brand technologies, Siemens, Waukesha, Wisconsin), previously examined for simultaneous biological nutrient removal (SBNR), was further evaluated using computational fluid dynamics (CFD). A CFD model was developed first by imparting the known momentum (calculated by tank fluid velocity and mass flowrate) to the fluid at the aeration disc region. Oxygen source (aeration) and sink (consumption) terms were introduced, and statistical analysis was applied to the CFD simulation results. The CFD model was validated with field data obtained from a test tank and a full-scale tank. The results indicated that CFD could predict the mixing pattern in closed-loop bioreactors. This enables visualization of the flow pattern, both with regard to flow velocity and dissolved-oxygen-distribution profiles. The velocity and oxygen-distribution gradients suggested that the flow patterns produced by directional aeration in closed-loop bioreactors created a heterogeneous environment that can result in dissolved oxygen variations throughout the bioreactor. Distinct anaerobic zones on a macroenvironment scale were not observed, but it is clear that, when flow passed around curves, a secondary spiral flow was generated. This second current, along with the main recirculation flow, could create alternating anaerobic and aerobic conditions vertically and horizontally, which would allow SBNR to occur. Reliable SBNR performance in Orbal oxidation ditches may be a result, at least in part, of such a spatially varying environment.
Piecewise-parabolic methods for astrophysical fluid dynamics
International Nuclear Information System (INIS)
Woodward, P.R.
1983-01-01
A general description of some modern numerical techniques for the simulation of astrophysical fluid flow is presented. The methods are introduced with a thorough discussion of the especially simple case of advection. Attention is focused on the piecewise-parabolic method (PPM). A description of the SLIC method for treating multifluid problems is also given. The discussion is illustrated by a number of advection and hydrodynamics test problems. Finally, a study of Kelvin-Helmholtz instability of supersonic jets using PPM with SLIC fluid interfaces is presented
Groves, Curtis Edward
2014-01-01
Spacecraft thermal protection systems are at risk of being damaged due to airflow produced from Environmental Control Systems. There are inherent uncertainties and errors associated with using Computational Fluid Dynamics to predict the airflow field around a spacecraft from the Environmental Control System. This paper describes an approach to quantify the uncertainty in using Computational Fluid Dynamics to predict airflow speeds around an encapsulated spacecraft without the use of test data. Quantifying the uncertainty in analytical predictions is imperative to the success of any simulation-based product. The method could provide an alternative to traditional validation by test only mentality. This method could be extended to other disciplines and has potential to provide uncertainty for any numerical simulation, thus lowering the cost of performing these verifications while increasing the confidence in those predictions.Spacecraft requirements can include a maximum airflow speed to protect delicate instruments during ground processing. Computational Fluid Dynamics can be used to verify these requirements; however, the model must be validated by test data. This research includes the following three objectives and methods. Objective one is develop, model, and perform a Computational Fluid Dynamics analysis of three (3) generic, non-proprietary, environmental control systems and spacecraft configurations. Several commercially available and open source solvers have the capability to model the turbulent, highly three-dimensional, incompressible flow regime. The proposed method uses FLUENT, STARCCM+, and OPENFOAM. Objective two is to perform an uncertainty analysis of the Computational Fluid Dynamics model using the methodology found in Comprehensive Approach to Verification and Validation of Computational Fluid Dynamics Simulations. This method requires three separate grids and solutions, which quantify the error bars around Computational Fluid Dynamics predictions
Groves, Curtis Edward
2014-01-01
Spacecraft thermal protection systems are at risk of being damaged due to airflow produced from Environmental Control Systems. There are inherent uncertainties and errors associated with using Computational Fluid Dynamics to predict the airflow field around a spacecraft from the Environmental Control System. This paper describes an approach to quantify the uncertainty in using Computational Fluid Dynamics to predict airflow speeds around an encapsulated spacecraft without the use of test data. Quantifying the uncertainty in analytical predictions is imperative to the success of any simulation-based product. The method could provide an alternative to traditional "validation by test only" mentality. This method could be extended to other disciplines and has potential to provide uncertainty for any numerical simulation, thus lowering the cost of performing these verifications while increasing the confidence in those predictions. Spacecraft requirements can include a maximum airflow speed to protect delicate instruments during ground processing. Computational Fluid Dynamics can be used to verify these requirements; however, the model must be validated by test data. This research includes the following three objectives and methods. Objective one is develop, model, and perform a Computational Fluid Dynamics analysis of three (3) generic, non-proprietary, environmental control systems and spacecraft configurations. Several commercially available and open source solvers have the capability to model the turbulent, highly three-dimensional, incompressible flow regime. The proposed method uses FLUENT, STARCCM+, and OPENFOAM. Objective two is to perform an uncertainty analysis of the Computational Fluid Dynamics model using the methodology found in "Comprehensive Approach to Verification and Validation of Computational Fluid Dynamics Simulations". This method requires three separate grids and solutions, which quantify the error bars around Computational Fluid Dynamics
Groves, Curtis E.
2013-01-01
Spacecraft thermal protection systems are at risk of being damaged due to airflow produced from Environmental Control Systems. There are inherent uncertainties and errors associated with using Computational Fluid Dynamics to predict the airflow field around a spacecraft from the Environmental Control System. This proposal describes an approach to validate the uncertainty in using Computational Fluid Dynamics to predict airflow speeds around an encapsulated spacecraft. The research described here is absolutely cutting edge. Quantifying the uncertainty in analytical predictions is imperative to the success of any simulation-based product. The method could provide an alternative to traditional"validation by test only'' mentality. This method could be extended to other disciplines and has potential to provide uncertainty for any numerical simulation, thus lowering the cost of performing these verifications while increasing the confidence in those predictions. Spacecraft requirements can include a maximum airflow speed to protect delicate instruments during ground processing. Computationaf Fluid Dynamics can be used to veritY these requirements; however, the model must be validated by test data. The proposed research project includes the following three objectives and methods. Objective one is develop, model, and perform a Computational Fluid Dynamics analysis of three (3) generic, non-proprietary, environmental control systems and spacecraft configurations. Several commercially available solvers have the capability to model the turbulent, highly three-dimensional, incompressible flow regime. The proposed method uses FLUENT and OPEN FOAM. Objective two is to perform an uncertainty analysis of the Computational Fluid . . . Dynamics model using the methodology found in "Comprehensive Approach to Verification and Validation of Computational Fluid Dynamics Simulations". This method requires three separate grids and solutions, which quantify the error bars around
DEFF Research Database (Denmark)
Wang, Weizhi; Wu, Minghao; Palm, Johannes
2018-01-01
mathematical models such as computational fluid dynamics are preferred and over the last 5 years, computational fluid dynamics has become more frequently used in the wave energy field. However, rigorous estimation of numerical errors, convergence rates and uncertainties associated with computational fluid...... for almost linear incident waves. First, we show that the computational fluid dynamics simulations have acceptable agreement to experimental data. We then present a verification and validation study focusing on the solution verification covering spatial and temporal discretization, iterative and domain......The wave loads and the resulting motions of floating wave energy converters are traditionally computed using linear radiation–diffraction methods. Yet for certain cases such as survival conditions, phase control and wave energy converters operating in the resonance region, more complete...
Onset of Dynamic Wetting Failure: The Influence of the Displaced Fluid
Vandre, Eric; Carvalho, Marcio; Kumar, Satish
2012-11-01
Dynamic wetting involves the displacement of fluid on a solid surface by an advancing liquid, and is essential to the successful operation of coating processes. In this work, we consider a model problem in order to examine the influence of the displaced fluid on the failure of dynamic wetting. Full two-dimensional (2D) calculations over a broad range of parameters are performed using the finite element method (FEM), and the results are compared to prior experiments and asymptotic analysis. This comparison motivates the development of a novel and efficient hybrid computational method that combines 2D FEM for the liquid and lubrication theory for the displaced fluid. We will discuss the limits of applicability of the hybrid approach, and its ability to describe realistic coating flows. Overall, our results highlight the significant influence of the displaced fluid on the conditions at which dynamic wetting failure occurs, along with the underlying physical mechanisms.
Chaotic population dynamics and biology of the top-predator
International Nuclear Information System (INIS)
Rai, Vikas; Upadhyay, Ranjit Kumar
2004-01-01
We study how the dynamics of a food chain depends on the biology of the top-predator. We consider two model food chains with specialist and generalist top-predators. Both types of food chains display same type of chaotic behavior, short-term recurrent chaos; but the generating mechanisms are drastically different. Food chains with specialist top-predators are dictated by exogenous stochastic factors. On the contrary, the dynamics of those with the generalist top-predator is governed by deterministic changes in system parameters. The study also suggests that robust chaos would be a rarity
Quantitative analysis of biological fluids by electron probe and X ray spectrometry
International Nuclear Information System (INIS)
Girod, Chantal
1986-01-01
In order to know the kidney normal operation and to have an insight on cellular transport mechanisms and hormonal regulations at the nephron level, a technique based on the use of an electron probe has been developed for the elemental analysis of micro-volumes of biological fluids. This academic document reports applications of this technique on animals on which such fluids have been sampled at different levels of the nephron. As these samples are available in too small volumes to be dosed by conventional methods, they have been quantitatively analysed by using an electronic probe based analyser in order to determine concentrations of all elements with an atomic number greater than that of carbon. After a presentation of the implemented method and hardware, the author thus describes how an analysis is performed, and reports and discusses an example (analysis conditions, data acquisition, data processing, minimum detectable concentration, reasons for measurement scattering)
Dynamic Simulation of Particles in a Magnetorheological Fluid
2008-06-01
12 E. INTERACTION WITH ELECTROMAGNET .................14 IV. MODEL FOR INTERACTION ................................17 A...using a magnetic field for use in a magnetic field clutch [2] and is considered the first to develop MR fluids. Although their works were conducted...usually a silicone oil) and the suspended particles (typically fine ferrous particles), is sandwiched in a small gap between two electromagnets . These
Topological Fluid Dynamics For Free and Viscous Surfaces
DEFF Research Database (Denmark)
Balci, Adnan
In an incompressible fluid flow, streamline patterns and their bifurcations are investigated close to wall for two-dimensional system and close to free and viscous surfaces in three-dimensional system. Expanding the velocity field in a Taylor series, we conduct a local analysis at the given...