WorldWideScience

Sample records for biological classification bullet

  1. Functions in Biological Kind Classification

    Science.gov (United States)

    Lombrozo, Tania; Rehder, Bob

    2012-01-01

    Biological traits that serve functions, such as a zebra's coloration (for camouflage) or a kangaroo's tail (for balance), seem to have a special role in conceptual representations for biological kinds. In five experiments, we investigate whether and why functional features are privileged in biological kind classification. Experiment 1…

  2. Biological signals classification and analysis

    CERN Document Server

    Kiasaleh, Kamran

    2015-01-01

    This authored monograph presents key aspects of signal processing analysis in the biomedical arena. Unlike wireless communication systems, biological entities produce signals with underlying nonlinear, chaotic nature that elude classification using the standard signal processing techniques, which have been developed over the past several decades for dealing primarily with standard communication systems. This book separates what is random from that which appears to be random, and yet is truly deterministic with random appearance. At its core, this work gives the reader a perspective on biomedical signals and the means to classify and process such signals. In particular, a review of random processes along with means to assess the behavior of random signals is also provided. The book also includes a general discussion of biological signals in order to demonstrate the inefficacy of the well-known techniques to correctly extract meaningful information from such signals. Finally, a thorough discussion of recently ...

  3. Cluster Bulleticity

    OpenAIRE

    Massey, Richard; Kitching, Thomas; Nagai, Daisuke

    2010-01-01

    The unique properties of dark matter are revealed during collisions between clusters of galaxies, such as the bullet cluster (1E 0657−56) and baby bullet (MACS J0025−12). These systems provide evidence for an additional, invisible mass in the separation between the distributions of their total mass, measured via gravitational lensing, and their ordinary ‘baryonic’ matter, measured via its X-ray emission. Unfortunately, the information available from these systems is limited by their rarity. C...

  4. Biological couplings: Classification and characteristic rules

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The phenomena that biological functions originate from biological coupling are the important biological foundation of multiple bionics and the significant discoveries in the bionic fields. In this paper, the basic concepts related to biological coupling are introduced from the bionic viewpoint. Constitution, classification and characteristic rules of biological coupling are illuminated, the general modes of biological coupling studies are analyzed, and the prospects of multi-coupling bionics are predicted.

  5. Rapid classification of biological components

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2013-10-15

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  6. Rapid classification of biological components

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  7. Rapid classification of biological components

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  8. Rapid classification of biological components

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2006-01-24

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

  9. Segmentation and classification of biological objects

    DEFF Research Database (Denmark)

    Schultz, Nette

    1995-01-01

    The present thesis is on segmentation and classification of biological objects using statistical methods. It is based on case studies dealing with different kinds of pork meat images, and we introduce appropriate statistical methods to solve the tasks in the case studies. The case studies concern...

  10. Saving our science from ourselves: the plight of biological classification

    Directory of Open Access Journals (Sweden)

    Malte C. Ebach

    2011-06-01

    Full Text Available Saving our science from ourselves: the plight of biological classification. Biological classification ( nomenclature, taxonomy, and systematics is being sold short. The desire for new technologies, faster and cheaper taxonomic descriptions, identifications, and revisions is symptomatic of a lack of appreciation and understanding of classification. The problem of gadget-driven science, a lack of best practice and the inability to accept classification as a descriptive and empirical science are discussed. The worst cases scenario is a future in which classifications are purely artificial and uninformative.

  11. Classification of Recombinant Biologics in the EU

    DEFF Research Database (Denmark)

    Klein, Kevin; De Bruin, Marie L; Broekmans, Andre W

    2015-01-01

    BACKGROUND AND OBJECTIVE: Biological medicinal products (biologics) are subject to specific pharmacovigilance requirements to ensure that biologics are identifiable by brand name and batch number in adverse drug reaction (ADR) reports. Since Member States collect ADR data at the national level...... of biologics by national authorities responsible for ADR reporting. METHODS: A sample list of recombinant biologics from the European Medicines Agency database of European Public Assessment Reports was created to analyze five Member States (Belgium, the Netherlands, Spain, Sweden, and the UK) according...

  12. [Classification of organisms and structuralism in biology].

    Science.gov (United States)

    Vasil'eva, L I

    2001-01-01

    Structuralism in biology is the oldest trend oriented to the search for natural "laws of forms" comparable with laws of growth of crystal, was revived at the end of 20th century on the basis of structuralist thought in socio-humanitarian sciences. The development of principal ideas of the linguistic structuralism in some aspects is similar to that of biological systematics, especially concerning the relationships between "system" and "evolution". However, apart from this general similarity, biological structuralism is strongly focused on familiar problems of the origin of diversity in nature. In their striving for the renovation of existing views, biological structuralists oppose the neo-darwinism emphasizing the existence of "law of forms", that are independent on heredity and genetic "determinism". The trend to develop so-called "rational taxonomy" is also characteristic of biological structuralism but this attempt failed being connected neither with Darwin's historicism nor with Plato's typology.

  13. How Many Kingdoms? Current Views of Biological Classification.

    Science.gov (United States)

    Margulis, Lynn

    1981-01-01

    Argues for the acceptance and use of a five-kingdom classification system for biology comprised of monera, protoctista, fungi, animals, and plants. Justifies the new system based upon the difference between prokaryotes and eukaryotes. Outlines each kingdom and describes its members. (DC)

  14. Literature classification for semi-automated updating of biological knowledgebases

    DEFF Research Database (Denmark)

    Olsen, Lars Rønn; Kudahl, Ulrich Johan; Winther, Ole

    2013-01-01

    abstracts yielded classification accuracy of 0.95, thus showing significant value in support of data extraction from the literature. Conclusion: We here propose a conceptual framework for semi-automated extraction of epitope data embedded in scientific literature using principles from text mining...... types of biological data, such as sequence data, are extensively stored in biological databases, functional annotations, such as immunological epitopes, are found primarily in semi-structured formats or free text embedded in primary scientific literature. Results: We defined and applied a machine...

  15. Histological image classification using biologically interpretable shape-based features

    International Nuclear Information System (INIS)

    Kothari, Sonal; Phan, John H; Young, Andrew N; Wang, May D

    2013-01-01

    Automatic cancer diagnostic systems based on histological image classification are important for improving therapeutic decisions. Previous studies propose textural and morphological features for such systems. These features capture patterns in histological images that are useful for both cancer grading and subtyping. However, because many of these features lack a clear biological interpretation, pathologists may be reluctant to adopt these features for clinical diagnosis. We examine the utility of biologically interpretable shape-based features for classification of histological renal tumor images. Using Fourier shape descriptors, we extract shape-based features that capture the distribution of stain-enhanced cellular and tissue structures in each image and evaluate these features using a multi-class prediction model. We compare the predictive performance of the shape-based diagnostic model to that of traditional models, i.e., using textural, morphological and topological features. The shape-based model, with an average accuracy of 77%, outperforms or complements traditional models. We identify the most informative shapes for each renal tumor subtype from the top-selected features. Results suggest that these shapes are not only accurate diagnostic features, but also correlate with known biological characteristics of renal tumors. Shape-based analysis of histological renal tumor images accurately classifies disease subtypes and reveals biologically insightful discriminatory features. This method for shape-based analysis can be extended to other histological datasets to aid pathologists in diagnostic and therapeutic decisions

  16. Substantiation of Biological Assets Classification Indexes for Enhancing Their Accounting Efficiency

    OpenAIRE

    Rayisa Tsyhan; Olha Chubka

    2013-01-01

    Present day national agricultural companies sell their products in both domestic and foreign markets which has a significant impact on specifics of biological assets accounting. The article offers biological assets classification provided in the Practical Guide to Accounting for Biological Assets and, besides, specifications proposed by various scientists. Based on the analysis, biological assets classification has been supplemented with new classification factors and their appropriateness ha...

  17. Effect of Process-Oriented Guided-Inquiry Learning on Non-majors Biology Students' Understanding of Biological Classification

    Science.gov (United States)

    Wozniak, Breann M.

    The purpose of this study was to examine the effect of process-oriented guided-inquiry learning (POGIL) on non-majors college biology students' understanding of biological classification. This study addressed an area of science instruction, POGIL in the non-majors college biology laboratory, which has yet to be qualitatively and quantitatively researched. A concurrent triangulation mixed methods approach was used. Students' understanding of biological classification was measured in two areas: scores on pre and posttests (consisting of 11 multiple choice questions), and conceptions of classification as elicited in pre and post interviews and instructor reflections. Participants were Minnesota State University, Mankato students enrolled in BIOL 100 Summer Session. One section was taught with the traditional curriculum (n = 6) and the other section in the POGIL curriculum (n = 10) developed by the researcher. Three students from each section were selected to take part in pre and post interviews. There were no significant differences within each teaching method (p familiar animal categories and aquatic habitats, unfamiliar organisms, combining and subdividing initial groupings, and the hierarchical nature of classification. The POGIL students were the only group to surpass these challenges after the teaching intervention. This study shows that POGIL is an effective technique at eliciting students' misconceptions, and addressing these misconceptions, leading to an increase in student understanding of biological classification.

  18. Integrative Chemical-Biological Read-Across Approach for Chemical Hazard Classification

    Science.gov (United States)

    Low, Yen; Sedykh, Alexander; Fourches, Denis; Golbraikh, Alexander; Whelan, Maurice; Rusyn, Ivan; Tropsha, Alexander

    2013-01-01

    Traditional read-across approaches typically rely on the chemical similarity principle to predict chemical toxicity; however, the accuracy of such predictions is often inadequate due to the underlying complex mechanisms of toxicity. Here we report on the development of a hazard classification and visualization method that draws upon both chemical structural similarity and comparisons of biological responses to chemicals measured in multiple short-term assays (”biological” similarity). The Chemical-Biological Read-Across (CBRA) approach infers each compound's toxicity from those of both chemical and biological analogs whose similarities are determined by the Tanimoto coefficient. Classification accuracy of CBRA was compared to that of classical RA and other methods using chemical descriptors alone, or in combination with biological data. Different types of adverse effects (hepatotoxicity, hepatocarcinogenicity, mutagenicity, and acute lethality) were classified using several biological data types (gene expression profiling and cytotoxicity screening). CBRA-based hazard classification exhibited consistently high external classification accuracy and applicability to diverse chemicals. Transparency of the CBRA approach is aided by the use of radial plots that show the relative contribution of analogous chemical and biological neighbors. Identification of both chemical and biological features that give rise to the high accuracy of CBRA-based toxicity prediction facilitates mechanistic interpretation of the models. PMID:23848138

  19. ROTATING BULLETS FROM A VARIABLE PROTOSTAR

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xuepeng [Purple Mountain Observatory, Chinese Academy of Sciences, 2 West Beijing Road, Nanjing 210008 (China); Arce, Héctor G. [Department of Astronomy, Yale University, Box 208101, New Haven, CT 06520-8101 (United States); Zhang, Qizhou [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Launhardt, Ralf; Henning, Thomas, E-mail: xpchen@pmo.ac.cn [Max Planck Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany)

    2016-06-20

    We present Submillimeter Array (SMA) CO (2–1) observations toward the protostellar jet driven by SVS 13 A, a variable protostar in the NGC 1333 star-forming region. The SMA CO (2–1) images show an extremely high-velocity jet composed of a series of molecular “bullets.” Based on the SMA CO observations, we discover clear and large systematic velocity gradients, perpendicular to the jet axis, in the blueshifted and redshifted bullets. After discussing several alternative interpretations, such as twin-jets, jet precession, warped disk, and internal helical shock, we suggest that the systematic velocity gradients observed in the bullets result from the rotation of the SVS 13 A jet. From the SMA CO images, the measured rotation velocities are 11.7–13.7 km s{sup −1} for the blueshifted bullet and 4.7 ± 0.5 km s{sup −1} for the redshifted bullet. The estimated specific angular momenta of the two bullets are comparable to those of dense cores, about 10 times larger than those of protostellar envelopes, and about 20 times larger than those of circumstellar disks. If the velocity gradients are due to the rotation of the SVS 13 A jet, the significant amount of specific angular momenta of the bullets indicates that the rotation of jets/outflows is a key mechanism to resolve the so-called “angular momentum problem” in the field of star formation. The kinematics of the bullets suggests that the jet launching footprint on the disk has a radius of ∼7.2–7.7 au, which appears to support the extended disk-wind model. We note that further observations are needed to comprehensively understand the kinematics of the SVS 13 A jet, in order to confirm the rotation nature of the bullets.

  20. Aspen biology, community classification, and management in the Blue Mountains

    Science.gov (United States)

    David K. Swanson; Craig L. Schmitt; Diane M. Shirley; Vicky Erickson; Kenneth J. Schuetz; Michael L. Tatum; David C. Powell

    2010-01-01

    Quaking aspen (Populus tremuloides Michx.) is a valuable species that is declining in the Blue Mountains of northeastern Oregon. This publication is a compilation of over 20 years of aspen management experience by USDA Forest Service workers in the Blue Mountains. It includes a summary of aspen biology and occurrence in the Blue Mountains, and a...

  1. Acoustic methods for measuring bullet velocity

    OpenAIRE

    Courtney, Michael

    2008-01-01

    This article describes two acoustic methods to measure bullet velocity with an accuracy of 1% or better. In one method, a microphone is placed within 0.1 m of the gun muzzle and a bullet is fired at a steel target 45 m away. The bullet's flight time is the recorded time between the muzzle blast and sound of hitting the target minus the time for the sound to return from the target to the microphone. In the other method, the microphone is placed equidistant from both the gun muzzle and the stee...

  2. A multitechnique approach for bullet characterization

    International Nuclear Information System (INIS)

    Sreenivas, K.; Venkatasubramanian, V.S.; Sankar Das, M.

    1978-01-01

    The possibility of using lead isotopic composition of bullet lead in conjunction with chemical composition (with respect to minor and trace elements) for the characterisation of bullet lead samples is demonstrated. Lead isotope analysis was done by using a mass spectrometer M.S. 702, while trace analyses were carried out by a combination of neutron activation analysis and atomic absorption spectrometry. It is pointed out that this multi-technique approach to the problem of bullet characterization can be gainfully employed in forensic investigations. (author)

  3. Isotopic analysis of bullet lead samples

    International Nuclear Information System (INIS)

    Sankar Das, M.; Venkatasubramanian, V.S.; Sreenivas, K.

    1976-01-01

    The possibility of using the isotopic composition of lead for the identification of bullet lead is investigated. Lead from several spent bullets were converted to lead sulphide and analysed for the isotopic abundances using an MS-7 mass spectrometer. The abundances are measured relative to that for Pb 204 was too small to permit differentiation, while the range of variation of Pb 206 and Pb 207 and the better precision in their analyses permitted differentiating samples from one another. The correlation among the samples examined has been pointed out. The method is complementary to characterisation of bullet leads by the trace element composition. The possibility of using isotopically enriched lead for tagging bullet lead is pointed out. (author)

  4. BIOCAT: a pattern recognition platform for customizable biological image classification and annotation.

    Science.gov (United States)

    Zhou, Jie; Lamichhane, Santosh; Sterne, Gabriella; Ye, Bing; Peng, Hanchuan

    2013-10-04

    Pattern recognition algorithms are useful in bioimage informatics applications such as quantifying cellular and subcellular objects, annotating gene expressions, and classifying phenotypes. To provide effective and efficient image classification and annotation for the ever-increasing microscopic images, it is desirable to have tools that can combine and compare various algorithms, and build customizable solution for different biological problems. However, current tools often offer a limited solution in generating user-friendly and extensible tools for annotating higher dimensional images that correspond to multiple complicated categories. We develop the BIOimage Classification and Annotation Tool (BIOCAT). It is able to apply pattern recognition algorithms to two- and three-dimensional biological image sets as well as regions of interest (ROIs) in individual images for automatic classification and annotation. We also propose a 3D anisotropic wavelet feature extractor for extracting textural features from 3D images with xy-z resolution disparity. The extractor is one of the about 20 built-in algorithms of feature extractors, selectors and classifiers in BIOCAT. The algorithms are modularized so that they can be "chained" in a customizable way to form adaptive solution for various problems, and the plugin-based extensibility gives the tool an open architecture to incorporate future algorithms. We have applied BIOCAT to classification and annotation of images and ROIs of different properties with applications in cell biology and neuroscience. BIOCAT provides a user-friendly, portable platform for pattern recognition based biological image classification of two- and three- dimensional images and ROIs. We show, via diverse case studies, that different algorithms and their combinations have different suitability for various problems. The customizability of BIOCAT is thus expected to be useful for providing effective and efficient solutions for a variety of biological

  5. An Evaluation of Peak Finding for DVR Classification of Biological Data

    KAUST Repository

    Knoll, Aaron

    2012-01-01

    In medicine and the life sciences, volume data are frequently entropic, containing numerous features at different scales as well as significant noise from the scan source. Conventional transfer function approaches for direct volume rendering have difficulty handling such data, resulting in poor classification or undersampled rendering. Peak finding addresses issues in classifying noisy data by explicitly solving for isosurfaces at desired peaks in a transfer function. As a result, one can achieve better classification and visualization with fewer samples and correspondingly higher performance. This paper applies peak finding to several medical and biological data sets, particularly examining its potential in directly rendering unfiltered and unsegmented data.

  6. A Biologically Inspired Approach to Frequency Domain Feature Extraction for EEG Classification

    Directory of Open Access Journals (Sweden)

    Nurhan Gursel Ozmen

    2018-01-01

    Full Text Available Classification of electroencephalogram (EEG signal is important in mental decoding for brain-computer interfaces (BCI. We introduced a feature extraction approach based on frequency domain analysis to improve the classification performance on different mental tasks using single-channel EEG. This biologically inspired method extracts the most discriminative spectral features from power spectral densities (PSDs of the EEG signals. We applied our method on a dataset of six subjects who performed five different imagination tasks: (i resting state, (ii mental arithmetic, (iii imagination of left hand movement, (iv imagination of right hand movement, and (v imagination of letter “A.” Pairwise and multiclass classifications were performed in single EEG channel using Linear Discriminant Analysis and Support Vector Machines. Our method produced results (mean classification accuracy of 83.06% for binary classification and 91.85% for multiclassification that are on par with the state-of-the-art methods, using single-channel EEG with low computational cost. Among all task pairs, mental arithmetic versus letter imagination yielded the best result (mean classification accuracy of 90.29%, indicating that this task pair could be the most suitable pair for a binary class BCI. This study contributes to the development of single-channel BCI, as well as finding the best task pair for user defined applications.

  7. Sparse Bayesian classification and feature selection for biological expression data with high correlations.

    Directory of Open Access Journals (Sweden)

    Xian Yang

    Full Text Available Classification models built on biological expression data are increasingly used to predict distinct disease subtypes. Selected features that separate sample groups can be the candidates of biomarkers, helping us to discover biological functions/pathways. However, three challenges are associated with building a robust classification and feature selection model: 1 the number of significant biomarkers is much smaller than that of measured features for which the search will be exhaustive; 2 current biological expression data are big in both sample size and feature size which will worsen the scalability of any search algorithms; and 3 expression profiles of certain features are typically highly correlated which may prevent to distinguish the predominant features. Unfortunately, most of the existing algorithms are partially addressing part of these challenges but not as a whole. In this paper, we propose a unified framework to address the above challenges. The classification and feature selection problem is first formulated as a nonconvex optimisation problem. Then the problem is relaxed and solved iteratively by a sequence of convex optimisation procedures which can be distributed computed and therefore allows the efficient implementation on advanced infrastructures. To illustrate the competence of our method over others, we first analyse a randomly generated simulation dataset under various conditions. We then analyse a real gene expression dataset on embryonal tumour. Further downstream analysis, such as functional annotation and pathway analysis, are performed on the selected features which elucidate several biological findings.

  8. A bullet-sired bone cyst

    Energy Technology Data Exchange (ETDEWEB)

    Brogdon, B.G. [University of South Alabama Medical Center, Department of Radiology, Mobile, AL (United States); Cottrell, W.C. [Orthopaedic Associates of West Florida, Clearwater, FL (United States); Nimityongskul, P. [University of South Alabama Medical Center, Department of Orthopaedic Surgery, Mobile, AL (United States); Takhtani, D. [Johns Hopkins School of Medicine, Department of Radiology, Baltimore, MD (United States)

    2006-12-15

    Random gunfire deposited a bullet in the proximal tibial metaphysis of a 9-year- old girl. The wound was not incapacitating and was treated conservatively. Within 17 months, soreness developed in the proximal leg, and radiography revealed a large unicameral cyst within which the bullet freely tumbled. Eventually, fear of impending fracture prompted further radiography, computed tomography, surgical intervention and pathological examination of the cyst wall. We believe this is only the second description in the English-language literature of this rare sequence of events. (orig.)

  9. A bullet-sired bone cyst

    International Nuclear Information System (INIS)

    Brogdon, B.G.; Cottrell, W.C.; Nimityongskul, P.; Takhtani, D.

    2006-01-01

    Random gunfire deposited a bullet in the proximal tibial metaphysis of a 9-year- old girl. The wound was not incapacitating and was treated conservatively. Within 17 months, soreness developed in the proximal leg, and radiography revealed a large unicameral cyst within which the bullet freely tumbled. Eventually, fear of impending fracture prompted further radiography, computed tomography, surgical intervention and pathological examination of the cyst wall. We believe this is only the second description in the English-language literature of this rare sequence of events. (orig.)

  10. Classification

    Science.gov (United States)

    Clary, Renee; Wandersee, James

    2013-01-01

    In this article, Renee Clary and James Wandersee describe the beginnings of "Classification," which lies at the very heart of science and depends upon pattern recognition. Clary and Wandersee approach patterns by first telling the story of the "Linnaean classification system," introduced by Carl Linnacus (1707-1778), who is…

  11. Effective automated feature construction and selection for classification of biological sequences.

    Directory of Open Access Journals (Sweden)

    Uday Kamath

    Full Text Available Many open problems in bioinformatics involve elucidating underlying functional signals in biological sequences. DNA sequences, in particular, are characterized by rich architectures in which functional signals are increasingly found to combine local and distal interactions at the nucleotide level. Problems of interest include detection of regulatory regions, splice sites, exons, hypersensitive sites, and more. These problems naturally lend themselves to formulation as classification problems in machine learning. When classification is based on features extracted from the sequences under investigation, success is critically dependent on the chosen set of features.We present an algorithmic framework (EFFECT for automated detection of functional signals in biological sequences. We focus here on classification problems involving DNA sequences which state-of-the-art work in machine learning shows to be challenging and involve complex combinations of local and distal features. EFFECT uses a two-stage process to first construct a set of candidate sequence-based features and then select a most effective subset for the classification task at hand. Both stages make heavy use of evolutionary algorithms to efficiently guide the search towards informative features capable of discriminating between sequences that contain a particular functional signal and those that do not.To demonstrate its generality, EFFECT is applied to three separate problems of importance in DNA research: the recognition of hypersensitive sites, splice sites, and ALU sites. Comparisons with state-of-the-art algorithms show that the framework is both general and powerful. In addition, a detailed analysis of the constructed features shows that they contain valuable biological information about DNA architecture, allowing biologists and other researchers to directly inspect the features and potentially use the insights obtained to assist wet-laboratory studies on retainment or modification

  12. Craniomaxillofacial falling bullet injuries and management.

    Science.gov (United States)

    Shuker, Sabri T; Sadda, Raid

    2010-07-01

    The purpose of this study was to bring attention to craniocerebral maxillofacial perforating/penetrating injuries due to AK-47 Kalashnikov falling bullets (FBs); these dangerous injuries to both civilians and soldiers are rare. A review of the literature shows no reports on AK-47 FBs leading to double craniocerebral perforation and settling into the maxillofacial region. The number of victims, the AK-47's availability, the associated morbidity and mortality rates, and the rarity of cases prompted this article. The treatment of injuries to the craniocerebral facial clinical profile due to FBs is challenging, and an understanding of the neurosurgical and maxillofacial management of these low-velocity FB injuries is required. We treated 11 cases due to AK-47 rifle FBs and 1 due to anti-aircraft Dashka 12.7-mm FBs. Craniocerebral facial injuries were treated and lodged bullets removed from different challenging locations in the base of the skull, without increasing morbidity and with avoidance of unnecessary surgical trauma to the affected area by the bullets. The required identification of such injuries can be difficult, and the removal of the lodged bullet to prevent secondary complications and reduce the chance of secondary infection can be graver than in other parts of the body. AK-47 FBs are a major public health concern internationally and require serious attention in terms of protection and management for civilians and soldiers in uniform. Copyright 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  13. Classification

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2017-01-01

    This article presents and discusses definitions of the term “classification” and the related concepts “Concept/conceptualization,”“categorization,” “ordering,” “taxonomy” and “typology.” It further presents and discusses theories of classification including the influences of Aristotle...... and Wittgenstein. It presents different views on forming classes, including logical division, numerical taxonomy, historical classification, hermeneutical and pragmatic/critical views. Finally, issues related to artificial versus natural classification and taxonomic monism versus taxonomic pluralism are briefly...

  14. Photonic Switching Devices Using Light Bullets

    Science.gov (United States)

    Goorjian, Peter M. (Inventor)

    1999-01-01

    A unique ultra-fast, all-optical switching device or switch is made with readily available, relatively inexpensive, highly nonlinear optical materials. which includes highly nonlinear optical glasses, semiconductor crystals and/or multiple quantum well semiconductor materials. At the specified wavelengths. these optical materials have a sufficiently negative group velocity dispersion and high nonlinear index of refraction to support stable light bullets. The light bullets counter-propagate through, and interact within the waveguide to selectively change each others' directions of propagation into predetermined channels. In one embodiment, the switch utilizes a rectangularly planar slab waveguide. and further includes two central channels and a plurality of lateral channels for guiding the light bullets into and out of the waveguide. An advantage of the present all-optical switching device lies in its practical use of light bullets, thus preventing the degeneration of the pulses due to dispersion and diffraction at the front and back of the pulses. Another advantage of the switching device is the relative insensitivity of the collision process to the time difference in which the counter-propagating pulses enter the waveguide. since. contrary to conventional co-propagating spatial solitons, the relative phase of the colliding pulses does not affect the interaction of these pulses. Yet another feature of the present all-optical switching device is the selection of the light pulse parameters which enables the generation of light bullets in nonlinear optical materials. including highly nonlinear optical glasses and semiconductor materials such as semiconductor crystals and/or multiple quantum well semiconductor materials.

  15. An accelerated framework for the classification of biological targets from solid-state micropore data.

    Science.gov (United States)

    Hanif, Madiha; Hafeez, Abdul; Suleman, Yusuf; Mustafa Rafique, M; Butt, Ali R; Iqbal, Samir M

    2016-10-01

    Micro- and nanoscale systems have provided means to detect biological targets, such as DNA, proteins, and human cells, at ultrahigh sensitivity. However, these devices suffer from noise in the raw data, which continues to be significant as newer and devices that are more sensitive produce an increasing amount of data that needs to be analyzed. An important dimension that is often discounted in these systems is the ability to quickly process the measured data for an instant feedback. Realizing and developing algorithms for the accurate detection and classification of biological targets in realtime is vital. Toward this end, we describe a supervised machine-learning approach that records single cell events (pulses), computes useful pulse features, and classifies the future patterns into their respective types, such as cancerous/non-cancerous cells based on the training data. The approach detects cells with an accuracy of 70% from the raw data followed by an accurate classification when larger training sets are employed. The parallel implementation of the algorithm on graphics processing unit (GPU) demonstrates a speedup of three to four folds as compared to a serial implementation on an Intel Core i7 processor. This incredibly efficient GPU system is an effort to streamline the analysis of pulse data in an academic setting. This paper presents for the first time ever, a non-commercial technique using a GPU system for realtime analysis, paired with biological cluster targeting analysis. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. Biological indices for classification of water quality around Mae Moh power plant, Thailand

    Directory of Open Access Journals (Sweden)

    Pongsarun Junshum and Siripen Traichaiyaporn

    2007-12-01

    Full Text Available The algal communities and water quality were monitored at eight sampling sites around Mae Moh power plant during January-December 2003. Three biological indices, viz. algal genus pollution index, saprobic index, and Shannon-Weaver index, were adopted to classify the water quality around the power plant in comparison with the measured physico-chemical water quality. The result shows that the Shannon-Weaver diversity index appears to be much more applicable and interpretable for the classification of water quality around the Mae Moh power plant than the algal genus pollution index and the saprobic index.

  17. Magnetic Bead—Magic Bullet

    Directory of Open Access Journals (Sweden)

    Christine Ruffert

    2016-01-01

    Full Text Available Microfluidics is assumed to be one of the leading and most promising areas of research since the early 1990s. In microfluidic systems, small spherical magnetic particles with superparamagnetic properties, called magnetic beads, play an important role in the design of innovative methods and tools, especially in bioanalysis and medical sciences. The intention of this review paper is to address main aspects from the state-of-the-art in the area of magnetic bead research, while demonstrating the broad variety of applications and the huge potential to solve fundamental biological and medical problems in the fields of diagnostics and therapy. Basic issues and demands related to the fabrication of magnetic particles and physical properties of nanosize magnets are discussed in Section 2. Of main interest are the control and adjustment of the nanoparticles’ properties and the availability of adequate approaches for particle detection via their magnetic field. Section 3 presents an overview of magnetic bead applications in nanomedicine. In Section 4, practical aspects of sample manipulation and separation employing magnetic beads are described. Finally, the benefits related to the use of magnetic bead-based microfluidic systems are summarized, illustrating ongoing questions and open tasks to be solved on the way to an approaching microfluidic age.

  18. Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assessment

    Directory of Open Access Journals (Sweden)

    Manzini Giovanni

    2007-07-01

    Full Text Available Abstract Background Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. However, the alignment methods seem inadequate for post-genomic studies since they do not scale well with data set size and they seem to be confined only to genomic and proteomic sequences. Therefore, alignment-free similarity measures are actively pursued. Among those, USM (Universal Similarity Metric has gained prominence. It is based on the deep theory of Kolmogorov Complexity and universality is its most novel striking feature. Since it can only be approximated via data compression, USM is a methodology rather than a formula quantifying the similarity of two strings. Three approximations of USM are available, namely UCD (Universal Compression Dissimilarity, NCD (Normalized Compression Dissimilarity and CD (Compression Dissimilarity. Their applicability and robustness is tested on various data sets yielding a first massive quantitative estimate that the USM methodology and its approximations are of value. Despite the rich theory developed around USM, its experimental assessment has limitations: only a few data compressors have been tested in conjunction with USM and mostly at a qualitative level, no comparison among UCD, NCD and CD is available and no comparison of USM with existing methods, both based on alignments and not, seems to be available. Results We experimentally test the USM methodology by using 25 compressors, all three of its known approximations and six data sets of relevance to Molecular Biology. This offers the first systematic and quantitative experimental assessment of this methodology, that naturally complements the many theoretical and the preliminary experimental results available. Moreover, we compare the USM methodology both with methods based on alignments and not. We may group our experiments into two sets. The first one, performed via ROC

  19. Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assessment.

    Science.gov (United States)

    Ferragina, Paolo; Giancarlo, Raffaele; Greco, Valentina; Manzini, Giovanni; Valiente, Gabriel

    2007-07-13

    Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. However, the alignment methods seem inadequate for post-genomic studies since they do not scale well with data set size and they seem to be confined only to genomic and proteomic sequences. Therefore, alignment-free similarity measures are actively pursued. Among those, USM (Universal Similarity Metric) has gained prominence. It is based on the deep theory of Kolmogorov Complexity and universality is its most novel striking feature. Since it can only be approximated via data compression, USM is a methodology rather than a formula quantifying the similarity of two strings. Three approximations of USM are available, namely UCD (Universal Compression Dissimilarity), NCD (Normalized Compression Dissimilarity) and CD (Compression Dissimilarity). Their applicability and robustness is tested on various data sets yielding a first massive quantitative estimate that the USM methodology and its approximations are of value. Despite the rich theory developed around USM, its experimental assessment has limitations: only a few data compressors have been tested in conjunction with USM and mostly at a qualitative level, no comparison among UCD, NCD and CD is available and no comparison of USM with existing methods, both based on alignments and not, seems to be available. We experimentally test the USM methodology by using 25 compressors, all three of its known approximations and six data sets of relevance to Molecular Biology. This offers the first systematic and quantitative experimental assessment of this methodology, that naturally complements the many theoretical and the preliminary experimental results available. Moreover, we compare the USM methodology both with methods based on alignments and not. We may group our experiments into two sets. The first one, performed via ROC (Receiver Operating Curve) analysis, aims at

  20. Using Variable Precision Rough Set for Selection and Classification of Biological Knowledge Integrated in DNA Gene Expression

    Directory of Open Access Journals (Sweden)

    Calvo-Dmgz D.

    2012-12-01

    Full Text Available DNA microarrays have contributed to the exponential growth of genomic and experimental data in the last decade. This large amount of gene expression data has been used by researchers seeking diagnosis of diseases like cancer using machine learning methods. In turn, explicit biological knowledge about gene functions has also grown tremendously over the last decade. This work integrates explicit biological knowledge, provided as gene sets, into the classication process by means of Variable Precision Rough Set Theory (VPRS. The proposed model is able to highlight which part of the provided biological knowledge has been important for classification. This paper presents a novel model for microarray data classification which is able to incorporate prior biological knowledge in the form of gene sets. Based on this knowledge, we transform the input microarray data into supergenes, and then we apply rough set theory to select the most promising supergenes and to derive a set of easy interpretable classification rules. The proposed model is evaluated over three breast cancer microarrays datasets obtaining successful results compared to classical classification techniques. The experimental results shows that there are not significat differences between our model and classical techniques but it is able to provide a biological-interpretable explanation of how it classifies new samples.

  1. Progressive Propaganda Critics and the Magic Bullet Myth.

    Science.gov (United States)

    Sproule, J. Michael

    1989-01-01

    Examines the development and historical inaccuracies of the "magic bullet" interpretation of American propaganda studies, which asserts that propaganda critics between the world wars treated messages as "magic bullets" directly and powerfully infused into passive receivers. Considers why this misconception of the progressive…

  2. iTools: a framework for classification, categorization and integration of computational biology resources.

    Directory of Open Access Journals (Sweden)

    Ivo D Dinov

    2008-05-01

    Full Text Available The advancement of the computational biology field hinges on progress in three fundamental directions--the development of new computational algorithms, the availability of informatics resource management infrastructures and the capability of tools to interoperate and synergize. There is an explosion in algorithms and tools for computational biology, which makes it difficult for biologists to find, compare and integrate such resources. We describe a new infrastructure, iTools, for managing the query, traversal and comparison of diverse computational biology resources. Specifically, iTools stores information about three types of resources--data, software tools and web-services. The iTools design, implementation and resource meta-data content reflect the broad research, computational, applied and scientific expertise available at the seven National Centers for Biomedical Computing. iTools provides a system for classification, categorization and integration of different computational biology resources across space-and-time scales, biomedical problems, computational infrastructures and mathematical foundations. A large number of resources are already iTools-accessible to the community and this infrastructure is rapidly growing. iTools includes human and machine interfaces to its resource meta-data repository. Investigators or computer programs may utilize these interfaces to search, compare, expand, revise and mine meta-data descriptions of existent computational biology resources. We propose two ways to browse and display the iTools dynamic collection of resources. The first one is based on an ontology of computational biology resources, and the second one is derived from hyperbolic projections of manifolds or complex structures onto planar discs. iTools is an open source project both in terms of the source code development as well as its meta-data content. iTools employs a decentralized, portable, scalable and lightweight framework for long

  3. Complete endoscopic management of a retained bullet in the bladder.

    Science.gov (United States)

    Friedman, Ariella A; Trinh, Quoc-Dien; Kaul, Sanjeev; Bhandari, Akshay

    2013-01-01

    A 25-year-old male gunshot victim presented at our institution with gross hematuria following Foley catheter insertion. Computed tomography and cystogram did not show a bladder perforation, but were notable for a left ischial fracture and the presence of a bullet within the bladder. After failed attempts at retrieving the bullet with a resectoscope and loop, as well as a cystoscope and stone crusher, a 26 French nephroscope was inserted transurethrally, and the bullet was successfully engaged and removed using a Perc NCircle (Cook Medical, Bloomington, IN) grasper. The extra-peritoneal injury was managed conservatively with catheter drainage. To our knowledge, this represents the first case of successful transurethral management of a retained intravesical bullet. Such an approach may benefit patients with retained intravesical bullets or other challenging intravesical foreign bodies and may be helpful in select circumstances to spare patients from more extensive surgeries.

  4. Application of Machine Learning to Proteomics Data: Classification and Biomarker Identification in Postgenomics Biology

    Science.gov (United States)

    Swan, Anna Louise; Mobasheri, Ali; Allaway, David; Liddell, Susan

    2013-01-01

    Abstract Mass spectrometry is an analytical technique for the characterization of biological samples and is increasingly used in omics studies because of its targeted, nontargeted, and high throughput abilities. However, due to the large datasets generated, it requires informatics approaches such as machine learning techniques to analyze and interpret relevant data. Machine learning can be applied to MS-derived proteomics data in two ways. First, directly to mass spectral peaks and second, to proteins identified by sequence database searching, although relative protein quantification is required for the latter. Machine learning has been applied to mass spectrometry data from different biological disciplines, particularly for various cancers. The aims of such investigations have been to identify biomarkers and to aid in diagnosis, prognosis, and treatment of specific diseases. This review describes how machine learning has been applied to proteomics tandem mass spectrometry data. This includes how it can be used to identify proteins suitable for use as biomarkers of disease and for classification of samples into disease or treatment groups, which may be applicable for diagnostics. It also includes the challenges faced by such investigations, such as prediction of proteins present, protein quantification, planning for the use of machine learning, and small sample sizes. PMID:24116388

  5. Cell adhesion during bullet motion in capillaries.

    Science.gov (United States)

    Takeishi, Naoki; Imai, Yohsuke; Ishida, Shunichi; Omori, Toshihiro; Kamm, Roger D; Ishikawa, Takuji

    2016-08-01

    A numerical analysis is presented of cell adhesion in capillaries whose diameter is comparable to or smaller than that of the cell. In contrast to a large number of previous efforts on leukocyte and tumor cell rolling, much is still unknown about cell motion in capillaries. The solid and fluid mechanics of a cell in flow was coupled with a slip bond model of ligand-receptor interactions. When the size of a capillary was reduced, the cell always transitioned to "bullet-like" motion, with a consequent decrease in the velocity of the cell. A state diagram was obtained for various values of capillary diameter and receptor density. We found that bullet motion enables firm adhesion of a cell to the capillary wall even for a weak ligand-receptor binding. We also quantified effects of various parameters, including the dissociation rate constant, the spring constant, and the reactive compliance on the characteristics of cell motion. Our results suggest that even under the interaction between P-selectin glycoprotein ligand-1 (PSGL-1) and P-selectin, which is mainly responsible for leukocyte rolling, a cell is able to show firm adhesion in a small capillary. These findings may help in understanding such phenomena as leukocyte plugging and cancer metastasis. Copyright © 2016 the American Physiological Society.

  6. Linking Biological Responses of Terrestrial N Eutrophication to the Final Ecosystem Goods and Services Classification System

    Science.gov (United States)

    Bell, M. D.; Clark, C.; Blett, T.

    2015-12-01

    The response of a biological indicator to N deposition can indicate that an ecosystem has surpassed a critical load and is at risk of significant change. The importance of this exceedance is often difficult to digest by policy makers and public audiences if the change is not linked to a familiar ecosystem endpoint. A workshop was held to bring together scientists, resource managers, and policy makers with expertise in ecosystem functioning, critical loads, and economics in an effort to identify the ecosystem services impacted by air pollution. This was completed within the framework of the Final Ecosystem Goods and Services (FEGS) Classification System to produce a product that identified distinct interactions between society and the effects of nitrogen pollution. From each change in a biological indicator, we created multiple ecological production functions to identify the cascading effects of the change to a measureable ecosystem service that a user interacts with either by enjoying, consuming, or appreciating the good or service, or using it as an input in the human economy. This FEGS metric was then linked to a beneficiary group that interacts with the service. Chains detailing the links from the biological indicator to the beneficiary group were created for aquatic and terrestrial acidification and eutrophication at the workshop, and here we present a subset of the workshop results by highlighting for 9 different ecosystems affected by terrestrial eutrophication. A total of 213 chains that linked to 37 unique FEGS metrics and impacted 15 beneficiary groups were identified based on nitrogen deposition mediated changes to biological indicators. The chains within each ecosystem were combined in flow charts to show the complex, overlapping relationships among biological indicators, ecosystem services, and beneficiary groups. Strength of relationship values were calculated for each chain based on support for the link in the scientific literature. We produced the

  7. Revealing Significant Relations between Chemical/Biological Features and Activity: Associative Classification Mining for Drug Discovery

    Science.gov (United States)

    Yu, Pulan

    2012-01-01

    Classification, clustering and association mining are major tasks of data mining and have been widely used for knowledge discovery. Associative classification mining, the combination of both association rule mining and classification, has emerged as an indispensable way to support decision making and scientific research. In particular, it offers a…

  8. Experimental studies on the plasma bullet propagation and its inhibition

    International Nuclear Information System (INIS)

    Karakas, Erdinc; Laroussi, Mounir

    2010-01-01

    Plasma bullets generated by atmospheric pressure low temperature plasma jets have recently been an active research topic due to their unique properties and their enhanced plasma chemistry. In this paper, experimental insights into the plasma bullet lifetime and its velocity are reported. Data obtained from intensified charge-coupled device camera and time-resolved optical emission spectroscopy (OES) elucidated the existence of a weakly ionized channel between the plasma bullet and its source (such as the plasma pencil). Factors responsible for the inhibition of the propagation of the bullet, such as low helium mole fraction, the magnitude of the applied voltage, and the secondary discharge ignition time, are also revealed. A new technique is discussed to accurately measure the plasma bullet velocity, using time-resolved OES. This new technique shows that during its lifetime the plasma bullet goes through launching, propagation, and ending phases. In addition, it is noted that the plasma bullet exhibits an unstable behavior at the early beginning and late ending of the propagation.

  9. BClass: A Bayesian Approach Based on Mixture Models for Clustering and Classification of Heterogeneous Biological Data

    Directory of Open Access Journals (Sweden)

    Arturo Medrano-Soto

    2004-12-01

    Full Text Available Based on mixture models, we present a Bayesian method (called BClass to classify biological entities (e.g. genes when variables of quite heterogeneous nature are analyzed. Various statistical distributions are used to model the continuous/categorical data commonly produced by genetic experiments and large-scale genomic projects. We calculate the posterior probability of each entry to belong to each element (group in the mixture. In this way, an original set of heterogeneous variables is transformed into a set of purely homogeneous characteristics represented by the probabilities of each entry to belong to the groups. The number of groups in the analysis is controlled dynamically by rendering the groups as 'alive' and 'dormant' depending upon the number of entities classified within them. Using standard Metropolis-Hastings and Gibbs sampling algorithms, we constructed a sampler to approximate posterior moments and grouping probabilities. Since this method does not require the definition of similarity measures, it is especially suitable for data mining and knowledge discovery in biological databases. We applied BClass to classify genes in RegulonDB, a database specialized in information about the transcriptional regulation of gene expression in the bacterium Escherichia coli. The classification obtained is consistent with current knowledge and allowed prediction of missing values for a number of genes. BClass is object-oriented and fully programmed in Lisp-Stat. The output grouping probabilities are analyzed and interpreted using graphical (dynamically linked plots and query-based approaches. We discuss the advantages of using Lisp-Stat as a programming language as well as the problems we faced when the data volume increased exponentially due to the ever-growing number of genomic projects.

  10. Physicomathematical Simulation Analysis for Small Bullets

    Directory of Open Access Journals (Sweden)

    D. P. Margaris

    2008-01-01

    Full Text Available A full six degrees of freedom (6-DOF flight dynamics model is proposed for the accurate prediction of short and long-range trajectories of small bullets via atmospheric flight to final impact point. The mathematical model is based on the full equations of motion set up in the no-roll body reference frame and is integrated numerically from given initial conditions at the firing site. The projectile maneuvering motion depends on the most significant force and moment variations, in addition to gravity and Magnus effect. The computational flight analysis takes into consideration the Mach number and total angle of attack effects by means of the variable aerodynamic coefficients. For the purposes of the present work, linear interpolation has been applied for aerodynamic coefficients from the official tabulated database. The developed computational method gives satisfactory agreement with published data of verified experiments and computational codes on atmospheric projectile trajectory analysis for various initial firing flight conditions.

  11. Using dual classifications in the development of avian wetland indices of biological integrity for wetlands in West Virginia, USA.

    Science.gov (United States)

    Veselka, Walter; Anderson, James T; Kordek, Walter S

    2010-05-01

    Considerable resources are being used to develop and implement bioassessment methods for wetlands to ensure that "biological integrity" is maintained under the United States Clean Water Act. Previous research has demonstrated that avian composition is susceptible to human impairments at multiple spatial scales. Using a site-specific disturbance gradient, we built avian wetland indices of biological integrity (AW-IBI) specific to two wetland classification schemes, one based on vegetative structure and the other based on the wetland's position in the landscape and sources of water. The resulting class-specific AW-IBI was comprised of one to four metrics that varied in their sensitivity to the disturbance gradient. Some of these metrics were specific to only one of the classification schemes, whereas others could discriminate varying levels of disturbance regardless of classification scheme. Overall, all of the derived biological indices specific to the vegetative structure-based classes of wetlands had a significant relation with the disturbance gradient; however, the biological index derived for floodplain wetlands exhibited a more consistent response to a local disturbance gradient. We suspect that the consistency of this response is due to the inherent nature of the connectivity of available habitat in floodplain wetlands.

  12. Mammographic quantitative image analysis and biologic image composition for breast lesion characterization and classification

    Energy Technology Data Exchange (ETDEWEB)

    Drukker, Karen, E-mail: kdrukker@uchicago.edu; Giger, Maryellen L.; Li, Hui [Department of Radiology, University of Chicago, Chicago, Illinois 60637 (United States); Duewer, Fred; Malkov, Serghei; Joe, Bonnie; Kerlikowske, Karla; Shepherd, John A. [Radiology Department, University of California, San Francisco, California 94143 (United States); Flowers, Chris I. [Department of Radiology, University of South Florida, Tampa, Florida 33612 (United States); Drukteinis, Jennifer S. [Department of Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 (United States)

    2014-03-15

    Purpose: To investigate whether biologic image composition of mammographic lesions can improve upon existing mammographic quantitative image analysis (QIA) in estimating the probability of malignancy. Methods: The study population consisted of 45 breast lesions imaged with dual-energy mammography prior to breast biopsy with final diagnosis resulting in 10 invasive ductal carcinomas, 5 ductal carcinomain situ, 11 fibroadenomas, and 19 other benign diagnoses. Analysis was threefold: (1) The raw low-energy mammographic images were analyzed with an established in-house QIA method, “QIA alone,” (2) the three-compartment breast (3CB) composition measure—derived from the dual-energy mammography—of water, lipid, and protein thickness were assessed, “3CB alone”, and (3) information from QIA and 3CB was combined, “QIA + 3CB.” Analysis was initiated from radiologist-indicated lesion centers and was otherwise fully automated. Steps of the QIA and 3CB methods were lesion segmentation, characterization, and subsequent classification for malignancy in leave-one-case-out cross-validation. Performance assessment included box plots, Bland–Altman plots, and Receiver Operating Characteristic (ROC) analysis. Results: The area under the ROC curve (AUC) for distinguishing between benign and malignant lesions (invasive and DCIS) was 0.81 (standard error 0.07) for the “QIA alone” method, 0.72 (0.07) for “3CB alone” method, and 0.86 (0.04) for “QIA+3CB” combined. The difference in AUC was 0.043 between “QIA + 3CB” and “QIA alone” but failed to reach statistical significance (95% confidence interval [–0.17 to + 0.26]). Conclusions: In this pilot study analyzing the new 3CB imaging modality, knowledge of the composition of breast lesions and their periphery appeared additive in combination with existing mammographic QIA methods for the distinction between different benign and malignant lesion types.

  13. Using two classification schemes to develop vegetation indices of biological integrity for wetlands in West Virginia, USA.

    Science.gov (United States)

    Veselka, Walter; Rentch, James S; Grafton, William N; Kordek, Walter S; Anderson, James T

    2010-11-01

    Bioassessment methods for wetlands, and other bodies of water, have been developed worldwide to measure and quantify changes in "biological integrity." These assessments are based on a classification system, meant to ensure appropriate comparisons between wetland types. Using a local site-specific disturbance gradient, we built vegetation indices of biological integrity (Veg-IBIs) based on two commonly used wetland classification systems in the USA: One based on vegetative structure and the other based on a wetland's position in a landscape and sources of water. The resulting class-specific Veg-IBIs were comprised of 1-5 metrics that varied in their sensitivity to the disturbance gradient (R2=0.14-0.65). Moreover, the sensitivity to the disturbance gradient increased as metrics from each of the two classification schemes were combined (added). Using this information to monitor natural and created wetlands will help natural resource managers track changes in biological integrity of wetlands in response to anthropogenic disturbance and allows the use of vegetative communities to set ecological performance standards for mitigation banks.

  14. Optical bullets and "rockets" in nonlinear dissipative systems and their transformations and interactions.

    Science.gov (United States)

    Soto-Crespo, J M; Grelu, Philippe; Akhmediev, Nail

    2006-05-01

    We demonstrate the existence of stable optical light bullets in nonlinear dissipative media for both cases of normal and anomalous chromatic dispersion. The prediction is based on direct numerical simulations of the (3+1)-dimensional complex cubic-quintic Ginzburg-Landau equation. We do not impose conditions of spherical or cylindrical symmetry. Regions of existence of stable bullets are determined in the parameter space. Beyond the domain of parameters where stable bullets are found, unstable bullets can be transformed into "rockets" i.e. bullets elongated in the temporal domain. A few examples of the interaction between two optical bullets are considered using spatial and temporal interaction planes.

  15. Assessment of bullet effectiveness based on a human vulnerability model.

    Science.gov (United States)

    Liu, Susu; Xu, C; Wen, Y; Li, G; Zhou, J

    2017-12-25

    Penetrating wounds from explosively propelled fragments and bullets are the most common causes of combat injury. There is a requirement to assess the potential effectiveness of bullets penetrating human tissues in order to optimise preventive measures and wound trauma management. An advanced voxel model based on the Chinese Visible Human data was built. A digital human vulnerability model was established in combination with wound reconstruction and vulnerability assessment rules, in which wound penetration profiles were obtained by recreating the penetration of projectiles into ballistic gelatin. An effectiveness evaluation method of bullet penetration using the Abbreviated Injury Scale (AIS) was developed and solved using the Monte Carlo sampling method. The effectiveness of rifle bullets was demonstrated to increase with increasing velocity in the range of 300-700 m/s. When imparting the same energy, the effectiveness of the 5.56 mm bullet was higher than the 7.62 mm bullet in this model. The superimposition of simulant penetration profiles produced from ballistic gelatin simulant has been used to predict wound tracts in damaged tissues. The authors recognise that determining clinical effectiveness based on the AIS scores alone without verification of outcome by review of clinical hospital records means that this technique should be seen more as a manner of comparing the effectiveness of bullets than an injury prediction model. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  16. The destabilizing effect of body armour on military rifle bullets.

    Science.gov (United States)

    Knudsen, P J; Sørensen, O H

    1997-01-01

    Soft body armour is designed to give protection against fragments and some low velocity bullets but is not designed to stop high velocity rifle bullets. Reports have claimed that soft body armour might disturb the stability of bullets that penetrate it, and that this might increase the size of the lesions. The reason for such an effect might be early yaw of the bullet, so we studied the behaviour of bullets which had passed through soft body armour. A 7.62 x 39 mm AK-47 rifle was fired from a permanent stand using full metal jacketed lead core bullets at a range of 30 m. Soft body armour composed for 14 and 28 layers of aramid fibres (Kevlar) was placed at 90 degrees and 60 degrees to the line of fire. Yaw was measured by the shadowgraph technique and a TERMA Doppler radar. A total of ten shots without body armour, and ten shots with each of the two types of body armour at the two angles were used. The results of the shadowgraph and Doppler radar measurements showed a proportional correlation between the two methods of determining the bullet yaw. The semiquantitative approach of the Doppler radar measurement was in agreement with the more concise measurement using the photographic technique. Velocity loss and loss of spin rate from penetrating 14 or 28 ply Kevlar was negligible. We observed induced instability after penetration of 14 and particularly 28 ply Kevlar, dependence of yaw with respect to the number of layers of Kevlar as well as to the angle of the body armour with respect to the line of fire.

  17. MO-DE-207B-03: Improved Cancer Classification Using Patient-Specific Biological Pathway Information Via Gene Expression Data

    Energy Technology Data Exchange (ETDEWEB)

    Young, M; Craft, D [Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States)

    2016-06-15

    Purpose: To develop an efficient, pathway-based classification system using network biology statistics to assist in patient-specific response predictions to radiation and drug therapies across multiple cancer types. Methods: We developed PICS (Pathway Informed Classification System), a novel two-step cancer classification algorithm. In PICS, a matrix m of mRNA expression values for a patient cohort is collapsed into a matrix p of biological pathways. The entries of p, which we term pathway scores, are obtained from either principal component analysis (PCA), normal tissue centroid (NTC), or gene expression deviation (GED). The pathway score matrix is clustered using both k-means and hierarchical clustering, and a clustering is judged by how well it groups patients into distinct survival classes. The most effective pathway scoring/clustering combination, per clustering p-value, thus generates various ‘signatures’ for conventional and functional cancer classification. Results: PICS successfully regularized large dimension gene data, separated normal and cancerous tissues, and clustered a large patient cohort spanning six cancer types. Furthermore, PICS clustered patient cohorts into distinct, statistically-significant survival groups. For a suboptimally-debulked ovarian cancer set, the pathway-classified Kaplan-Meier survival curve (p = .00127) showed significant improvement over that of a prior gene expression-classified study (p = .0179). For a pancreatic cancer set, the pathway-classified Kaplan-Meier survival curve (p = .00141) showed significant improvement over that of a prior gene expression-classified study (p = .04). Pathway-based classification confirmed biomarkers for the pyrimidine, WNT-signaling, glycerophosphoglycerol, beta-alanine, and panthothenic acid pathways for ovarian cancer. Despite its robust nature, PICS requires significantly less run time than current pathway scoring methods. Conclusion: This work validates the PICS method to improve

  18. Aerial firing and stray bullet injuries: a rising tide.

    Science.gov (United States)

    Ali, Syed Asad; Tahir, Syed Mohammad; Makhdoom, Asadullah; Shaikh, Abdul Razaque; Siddique, Akmal Jamal

    2015-04-01

    Aerial firing is shooting, using fire arm, into the air usually during a celebration. This observational study aimed to quantify magnitude and impact of stray bullet injuries by aerial firing at surgical emergencies of the Liaquat University Hospital (a university hospital), Hyderabad, Sindh, Pakistan from January 2009 to December 2010 (2 years). During the study period, 144 firearm injuries due to stray bullet reported to the A and E departments of the university hospital. All patients referred to surgical unit providing emergency cover on that day irrespective of the severity of the injury for medico-legal reasons. For this study, the cases were divided into those having trivial injury and do not require any active surgical intervention and those having serious injury mandating surgical intervention. One hundred and two cases of stray bullet injury sustained trivial injury and followed as outpatients after an overnight period of indoor hospitalization; however, 42 patients with stray bullet injuries requiring surgical intervention were hospitalized. The most common events leading to aerial firing and stray bullet injuries were marriage ceremonies, followed by a political rallies and New Year celebrations. Stray bullet injury also reported after aerial firing on cricket/hockey team victories, Pakistan Independence Day (14th August), cultural day in Sindh and Basant (Kite) festival in Punjab. The most frequent sites with serious stray bullet injury were chest (15), head and neck (10), abdomen (9) and limbs (8), respectively. Surgical interventions performed included chest intubation, exploration of wound tract to retrieve bullet if lodged superficially and was palpable, laparotomy to managed intra-abdominal injury, reduction of fracture site followed by reconstruction, flap reconstruction and graft for nonhealing wound. The mean duration of hospital stay was 19 days. No mortality was observed in this series of patients. We conclude that the prevalence of aerial

  19. EDITORIAL: Plasma jets and plasma bullets Plasma jets and plasma bullets

    Science.gov (United States)

    Kong, M. G.; Ganguly, B. N.; Hicks, R. F.

    2012-06-01

    -mentioned early studies has witnessed a considerable and exciting growth in terms of new phenomena observed, new physics and chemistry uncovered, new plasma jet sources conceived, and new applications developed. Examples include the observations of plasma bullets on a nanosecond scale [16], the similarity of plasma bullets to streamers [17], arrays of plasma jets as metamaterials [18], and a rapid increase of applications in biomedicine [19]. However the considerable growth in the research of plasma jets has not been adequately supported, so far, by a sound fundamental underpinning, partly resulting from a somewhat underdevelopment of effective diagnostics and modelling tools. Recognizing the critical importance of basic science for future growth of low-temperature plasma jet technology, this special issue on plasma jets and bullets aims to address some of the most important fundamental questions. Many of the special issue papers continue the established line of investigation to characterize the formation of plasma bullets, using typically ultrafast imaging, electrical detection including electric field and plasma conductivity measurement, and optical emission spectrometry [20]-[26]. These offer strong experimental evidence for the well-known hypothesis that a plasma jet is a form of streamer, and that the ionization wave plays a critical role in their formation. The interaction of two parallel plasma jets [27] and manipulation of plasma jet characteristics [28, 29] are also reported using a similar combination of experimental techniques. Some of the common characteristics of plasma jets are summarized in a review paper in this special issue [30]. A somewhat different line of investigation is employed in a detailed experimental characterization of deterministic chaos in atmospheric plasma jets [31], one of the few non-bullet modes of plasma jets. Although chaos in ionized gases have been observed in other types of discharge plasmas, their applications have not so far been linked

  20. Dissipative light-bullets in the filamentation of femtosecond pulses

    International Nuclear Information System (INIS)

    Porras, M.A.; Gonzalo, I.

    2010-01-01

    Complete text of publication follows. With the growing interest in filamentation in solid and liquid media, the regime of filamentation with anomalous dispersion is receiving more attention. In this work we show that basics aspects of the filament dynamics in this regime can be explained in terms of a novel type of light-bullet, which is not of solitary or of conical types, but a wave-packet that maximizes the energy dissipation into the medium while remaining localized and stationary in propagation. We first show that a nonlinear optical medium at a given carrier wave length at which dispersion is anomalous, supports 'dissipative' light-bullets, i.e., waves localized in space and time and that propagate without change as a result of a balance between nonlinear compression and nonlinear absorption. Among them, the particular dissipative light-bullet with the highest possible dissipation is unique in a given medium, in the sense that all its properties are fixed by the properties of the medium at the carrier wave length. In this light-bullet, self-focusing continuously transports energy towards the pulse center by an amount that just compensates for the nonlinear losses. Figure 1(a) shows the radial profiles of the dissipative light-bullets that maximizes energy dissipation for several orders of multi-photon absorption responsible for the nonlinear losses. We have also found that this dissipative light-bullet tends to be spontaneously formed in the filamentary dynamics in media with anomalous dispersion. Figure 1(b) shows the peak intensity, the total energy and losses of a pulse that undergoes self-focusing and filamentation in an ideal medium with only Kerr nonlinearity and multi-photon absorption. This simple model reproduces the particularly long filament 'segments' and the 'burst' observed in experiments and in more accurate simulations. The peak intensity in the filament is identical to that of the dissipative light-bullet with maximum dissipation, and the

  1. Automated Processing of Imaging Data through Multi-tiered Classification of Biological Structures Illustrated Using Caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Mei Zhan

    2015-04-01

    Full Text Available Quantitative imaging has become a vital technique in biological discovery and clinical diagnostics; a plethora of tools have recently been developed to enable new and accelerated forms of biological investigation. Increasingly, the capacity for high-throughput experimentation provided by new imaging modalities, contrast techniques, microscopy tools, microfluidics and computer controlled systems shifts the experimental bottleneck from the level of physical manipulation and raw data collection to automated recognition and data processing. Yet, despite their broad importance, image analysis solutions to address these needs have been narrowly tailored. Here, we present a generalizable formulation for autonomous identification of specific biological structures that is applicable for many problems. The process flow architecture we present here utilizes standard image processing techniques and the multi-tiered application of classification models such as support vector machines (SVM. These low-level functions are readily available in a large array of image processing software packages and programming languages. Our framework is thus both easy to implement at the modular level and provides specific high-level architecture to guide the solution of more complicated image-processing problems. We demonstrate the utility of the classification routine by developing two specific classifiers as a toolset for automation and cell identification in the model organism Caenorhabditis elegans. To serve a common need for automated high-resolution imaging and behavior applications in the C. elegans research community, we contribute a ready-to-use classifier for the identification of the head of the animal under bright field imaging. Furthermore, we extend our framework to address the pervasive problem of cell-specific identification under fluorescent imaging, which is critical for biological investigation in multicellular organisms or tissues. Using these examples as a

  2. Automated Processing of Imaging Data through Multi-tiered Classification of Biological Structures Illustrated Using Caenorhabditis elegans.

    Science.gov (United States)

    Zhan, Mei; Crane, Matthew M; Entchev, Eugeni V; Caballero, Antonio; Fernandes de Abreu, Diana Andrea; Ch'ng, QueeLim; Lu, Hang

    2015-04-01

    Quantitative imaging has become a vital technique in biological discovery and clinical diagnostics; a plethora of tools have recently been developed to enable new and accelerated forms of biological investigation. Increasingly, the capacity for high-throughput experimentation provided by new imaging modalities, contrast techniques, microscopy tools, microfluidics and computer controlled systems shifts the experimental bottleneck from the level of physical manipulation and raw data collection to automated recognition and data processing. Yet, despite their broad importance, image analysis solutions to address these needs have been narrowly tailored. Here, we present a generalizable formulation for autonomous identification of specific biological structures that is applicable for many problems. The process flow architecture we present here utilizes standard image processing techniques and the multi-tiered application of classification models such as support vector machines (SVM). These low-level functions are readily available in a large array of image processing software packages and programming languages. Our framework is thus both easy to implement at the modular level and provides specific high-level architecture to guide the solution of more complicated image-processing problems. We demonstrate the utility of the classification routine by developing two specific classifiers as a toolset for automation and cell identification in the model organism Caenorhabditis elegans. To serve a common need for automated high-resolution imaging and behavior applications in the C. elegans research community, we contribute a ready-to-use classifier for the identification of the head of the animal under bright field imaging. Furthermore, we extend our framework to address the pervasive problem of cell-specific identification under fluorescent imaging, which is critical for biological investigation in multicellular organisms or tissues. Using these examples as a guide, we envision

  3. Management of migrating intracranial bullets: lessons learned from surviving an AK-47 bullet through the lateral brainstem.

    Science.gov (United States)

    Rammo, Richard A; DeFazio, Michael V; Bullock, M Ross

    2012-01-01

    Survival after a gunshot wound (GSW) to the head is becoming more common, with an accompanying increase in spontaneous migration of these intracranial bullet fragments. This phenomenon is well described in current literature and is a potentially life-threatening delayed complication of GSW to the head. We present the case of a 17-year-old boy who survived a penetrating GSW to the cranium and cerebellum after an accident involving an AK (Automatic Kalashnikov)-47 (7.62 mm). Following initial attempts to remove the bullet and associated hematoma from the cerebellar hemisphere, intraoperative fluoroscopy revealed that the bullet had migrated to lie within the right middle cerebellar peduncle with the development of intraoperative cardiac arrhythmia. The bullet could not be retrieved without risk of damage to the superior and inferior cerebellar arteries. The patient then developed bacterial meningitis, and further imaging revealed the bullet had again migrated under the cerebellar cortex to an accessible location. The infection was treated with aggressive antibiotic therapy and the bullet was removed from the posterior fossa, thus preventing recurrence of infection and further migration. The patient regained full motor, speech, and proprioceptive function within months after injury. The potential for spontaneous migration exists with any penetrating brain injury involving a retained foreign body. When a retained intracranial foreign body is unable to be safely extracted during initial debridement, close clinical evaluation is essential and plain-film or computed tomographic imaging should be considered in order to enhance the early detection of delayed-onset life-threatening deterioration, such as meningitis and occlusion of cerebrospinal fluid drainage, because of spontaneous migration. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. Comparison of Principal Component Analysis and Linear Discriminant Analysis applied to classification of excitation-emission matrices of the selected biological material

    Directory of Open Access Journals (Sweden)

    Maciej Leśkiewicz

    2016-03-01

    Full Text Available Quality of two linear methods (PCA and LDA applied to reduce dimensionality of feature analysis is compared and efficiency of their algorithms in classification of the selected biological materials according to their excitation-emission fluorescence matrices is examined. It has been found that LDA method reduces the dimensions (or a number of significant variables more effectively than PCA method. A relatively good discrimination within the examined biological material has been obtained with the use of LDA algorithm.[b]Keywords[/b]: Feature Analysis, Fluorescence Spectroscopy, Biological Material Classification

  5. Biological validation of physical coastal waters classification along the NE Atlantic region based on rocky macroalgae distribution

    Science.gov (United States)

    Ramos, Elvira; Puente, Araceli; Juanes, José Antonio; Neto, João M.; Pedersen, Are; Bartsch, Inka; Scanlan, Clare; Wilkes, Robert; Van den Bergh, Erika; Ar Gall, Erwan; Melo, Ricardo

    2014-06-01

    A methodology to classify rocky shores along the North East Atlantic (NEA) region was developed. Previously, biotypes and the variability of environmental conditions within these were recognized based on abiotic data. A biological validation was required in order to support the ecological meaning of the physical typologies obtained. A database of intertidal macroalgae species occurring in the coastal area between Norway and the South Iberian Peninsula was generated. Semi-quantitative abundance data of the most representative macroalgal taxa were collected in three levels: common, rare or absent. Ordination and classification multivariate analyses revealed a clear latitudinal gradient in the distribution of macroalgae species resulting in two distinct groups: one northern and one southern group, separated at the coast of Brittany (France). In general, the results based on biological data coincided with the results based on physical characteristics. The ecological meaning of the coastal waters classification at a broad scale shown in this work demonstrates that it can be valuable as a practical tool for conservation and management purposes.

  6. Objective classification of latent behavioral states in bio-logging data using multivariate-normal hidden Markov models.

    Science.gov (United States)

    Phillips, Joe Scutt; Patterson, Toby A; Leroy, Bruno; Pilling, Graham M; Nicol, Simon J

    2015-07-01

    many different types of noisy autocorrelated data, as typically found across a range of ecological systems. Summarizing time-series data into a multivariate assemblage of dimensions relevant to the desired classification provides a means to examine these data in an appropriate behavioral space. We discuss how outputs of these models can be applied to bio-logging and other imperfect behavioral data, providing easily interpretable models for hypothesis testing.

  7. Bullet embolism of pulmonary artery: a case report

    Directory of Open Access Journals (Sweden)

    Mauricio Gustavo Ieiri Yamanari

    2014-04-01

    Full Text Available The authors report the case of a patient victim of gunshots, with a very rare complication: venous bullet embolism from the left external iliac vein to the lingular segment of the left pulmonary artery. Diagnosis is made with whole-body radiography or computed tomography. Digital angiography is reserved for supplementary diagnosis or to be used as a therapeutic procedure.

  8. Tear Gas, Expanding Bullets and Plain-Clothed Personnel

    DEFF Research Database (Denmark)

    Wiesener, Cornelius Rust

    2017-01-01

    This article examines the interplay between human rights law and humanitarian law in relation to riot control agents (such as tear gas), expanding bullets and plain-clothed forces. While outlawed under humanitarian law, they are widely used by police in peace time and not subject to similar bans...

  9. Bullet Points, New Writing, and the Marketization of Public Discourse

    DEFF Research Database (Denmark)

    van Leeuwen, Theo; Djonov, Emilia

    2014-01-01

    Bullet lists epitomize both new writing practices, which are promoted through ubiquitous software such as Microsoft's PowerPoint, and the marketization of public discourse. The argument is illustrated with an analysis of the recontextualization of the Australian Treasurer's Budget speech...

  10. A Bullet-Block Experiment that Explains the Chain Fountain

    Science.gov (United States)

    Pantaleone, J.; Smith, R.

    2018-05-01

    It is common in science for two phenomena to appear to be very different, but in fact follow from the same basic principles. Here we consider such a case, the connection between the chain fountain and a bullet-block collision experiment. When an upward moving bullet strikes a wooden block resting on a horizontal table, the block will rise to a higher height when the bullet strikes near the end of the block. This is because the quickly rotating block experiences an additional upward "reaction" force from its contact with the table. Such a reaction force also explains the chain fountain. When a chain falls from a pile in a container to the floor below, the chain rises up above the container. This rise occurs because the quickly rotating links in the container push off of the surface beneath them. We derive a model that accurately describes our measurements in the bullet-block experiment, and then use this same model to calculate an approximate expression for the distance the chain rises above the container. More extensive discussions of the chain fountain are available elsewhere.

  11. Atypical gunshot wound: Bullet trajectory analyzed by computed tomography

    Directory of Open Access Journals (Sweden)

    Tae Ro

    2015-01-01

    Conclusion: If an abnormal trajectory is maintained, it is possible for a bullet to traverse half the length of the body without the patient realizing it. Accurate CT analysis and quick decisions in surgical and medical management are critical takeaways to provide quality care to patients with these injuries.

  12. Bullet embolism of pulmonary artery: a case report

    International Nuclear Information System (INIS)

    Yamanari, Mauricio Gustavo Ieiri; Mansur, Maria Clara Dias; Kay, Fernando Uliana; Silverio, Paulo Rogerio Barboza; Jayanthi, Shri Krishna; Funari, Marcelo Buarque de Gusmao

    2014-01-01

    The authors report the case of a patient victim of gunshots, with a very rare complication: venous bullet embolism from the left external iliac vein to the lingular segment of the left pulmonary artery. Diagnosis is made with whole-body radiography or computed tomography. Digital angiography is reserved for supplementary diagnosis or to be used as a therapeutic procedure. (author)

  13. Simulation of impact ballistic of Cu-10wt%Sn frangible bullet using smoothed particle hydrodynamics

    Science.gov (United States)

    Hidayat, Mas Irfan P.; Widyastuti, Simaremare, Peniel

    2018-04-01

    Frangible bullet is designed to disintegrate upon impact against a hard target. Understanding the impact response and performance of frangible bullet is therefore of highly interest. In this paper, simulation of impact ballistic of Cu-IOwt%Sn frangible bullet using smoothed particle hydrodynamics (SPH) method is presented. The frangible bullet is impacted against a hard, cylindrical stainless steel target. Effect of variability of the frangible bullet material properties due to the variation of sintering temperature in its manufacturing process to the bullet frangibility factor (FF) is investigated numerically. In addition, the bullet kinetic energy during impact as well as its ricochet and fragmentation are also examined and simulated. Failure criterion based upon maximum strain is employed in the simulation. It is shown that the SPH simulation can produce good estimation for kinetic energy of bullet after impact, thus giving the FF prediction with respect to the variation of frangible bullet material properties. In comparison to explicit finite element (FE) simulation, in which only material/element deletion is shown, convenience in showing frangible bullet fragmentation is shown using the SPH simulation. As a result, the effect of sintering temperature to the way of the frangible bullet fragmented can be also observed clearly.

  14. A self-adherent, bullet-shaped microneedle patch for controlled transdermal delivery of insulin.

    Science.gov (United States)

    Seong, Keum-Yong; Seo, Min-Soo; Hwang, Dae Youn; O'Cearbhaill, Eoin D; Sreenan, Seamus; Karp, Jeffrey M; Yang, Seung Yun

    2017-11-10

    Proteins are important biologic therapeutics used for the treatment of various diseases. However, owing to low bioavailability and poor skin permeability, transdermal delivery of protein therapeutics poses a significant challenge. Here, we present a new approach for transdermal protein delivery using bullet-shaped double-layered microneedle (MN) arrays with water-swellable tips. This design enabled the MNs to mechanically interlock with soft tissues by selective distal swelling after skin insertion. Additionally, prolonged release of loaded proteins by passive diffusion through the swollen tips was obtained. The bullet-shaped MNs provided an optimal geometry for mechanical interlocking, thereby achieving significant adhesion strength (~1.6Ncm -2 ) with rat skin. By harnessing the MN's reversible swelling/deswelling property, insulin, a model protein drug, was loaded in the swellable tips using a mild drop/dry procedure. The insulin-loaded MN patch released 60% of insulin when immersed in saline over the course of 12h and approximately 70% of the released insulin appeared to have preserved structural integrity. An in vivo pilot study showed a prolonged release of insulin from swellable MN patches, leading to a gradual decrease in blood glucose levels. This self-adherent transdermal MN platform can be applied to a variety of protein drugs requiring sustained release kinetics. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Are lead-free hunting rifle bullets as effective at killing wildlife as conventional lead bullets? A comparison based on wound size and morphology

    Energy Technology Data Exchange (ETDEWEB)

    Trinogga, Anna, E-mail: anna_trinogga@gmx.de; Fritsch, Guido; Hofer, Heribert; Krone, Oliver

    2013-01-15

    Fragmentation of the lead core of conventional wildlife hunting rifle bullets causes contamination of the target with lead. The community of scavenger species which feed on carcasses or viscera discarded by hunters are regularly exposed to these lead fragments and may die by acute or chronic lead intoxication, as demonstrated for numerous species such as white-tailed eagles (Haliaeetus albicilla) where it is among the most important sources of mortality. Not only does hunting with conventional ammunition deposit lead in considerable quantities in the environment, it also significantly delays or threatens the recovery of endangered raptor populations. Although lead-free bullets might be considered a suitable alternative that addresses the source of these problems, serious reservations have been expressed as to their ability to quickly and effectively kill a hunted animal. To assess the suitability of lead-free projectiles for hunting practice, the wounding potential of conventional bullets was compared with lead-free bullets under real life hunting conditions. Wound dimensions were regarded as good markers of the projectiles' killing potential. Wound channels in 34 killed wild ungulates were evaluated using computed tomography and post-mortem macroscopical examination. Wound diameters caused by conventional bullets did not differ significantly to those created by lead-free bullets. Similarly, the size of the maximum cross-sectional area of the wound was similar for both bullet types. Injury patterns suggested that all animals died by exsanguination. This study demonstrates that lead-free bullets are equal to conventional hunting bullets in terms of killing effectiveness and thus equally meet the welfare requirements of killing wildlife as painlessly as possible. The widespread introduction and use of lead-free bullets should be encouraged as it prevents environmental contamination with a seriously toxic pollutant and contributes to the conservation of a wide

  16. Are lead-free hunting rifle bullets as effective at killing wildlife as conventional lead bullets? A comparison based on wound size and morphology

    International Nuclear Information System (INIS)

    Trinogga, Anna; Fritsch, Guido; Hofer, Heribert; Krone, Oliver

    2013-01-01

    Fragmentation of the lead core of conventional wildlife hunting rifle bullets causes contamination of the target with lead. The community of scavenger species which feed on carcasses or viscera discarded by hunters are regularly exposed to these lead fragments and may die by acute or chronic lead intoxication, as demonstrated for numerous species such as white-tailed eagles (Haliaeetus albicilla) where it is among the most important sources of mortality. Not only does hunting with conventional ammunition deposit lead in considerable quantities in the environment, it also significantly delays or threatens the recovery of endangered raptor populations. Although lead-free bullets might be considered a suitable alternative that addresses the source of these problems, serious reservations have been expressed as to their ability to quickly and effectively kill a hunted animal. To assess the suitability of lead-free projectiles for hunting practice, the wounding potential of conventional bullets was compared with lead-free bullets under real life hunting conditions. Wound dimensions were regarded as good markers of the projectiles' killing potential. Wound channels in 34 killed wild ungulates were evaluated using computed tomography and post-mortem macroscopical examination. Wound diameters caused by conventional bullets did not differ significantly to those created by lead-free bullets. Similarly, the size of the maximum cross-sectional area of the wound was similar for both bullet types. Injury patterns suggested that all animals died by exsanguination. This study demonstrates that lead-free bullets are equal to conventional hunting bullets in terms of killing effectiveness and thus equally meet the welfare requirements of killing wildlife as painlessly as possible. The widespread introduction and use of lead-free bullets should be encouraged as it prevents environmental contamination with a seriously toxic pollutant and contributes to the conservation of a wide variety

  17. Artificial intelligence in label-free microscopy biological cell classification by time stretch

    CERN Document Server

    Mahjoubfar, Ata; Jalali, Bahram

    2017-01-01

    This book introduces time-stretch quantitative phase imaging (TS-QPI), a high-throughput label-free imaging flow cytometer developed for big data acquisition and analysis in phenotypic screening. TS-QPI is able to capture quantitative optical phase and intensity images simultaneously, enabling high-content cell analysis, cancer diagnostics, personalized genomics, and drug development. The authors also demonstrate a complete machine learning pipeline that performs optical phase measurement, image processing, feature extraction, and classification, enabling high-throughput quantitative imaging that achieves record high accuracy in label -free cellular phenotypic screening and opens up a new path to data-driven diagnosis. • Demonstrates how machine learning is used in high-speed microscopy imaging to facilitate medical diagnosis; • Provides a systematic and comprehensive illustration of time stretch technology; • Enables multidisciplinary application, including industrial, biomedical, and artificial intell...

  18. Biological characteristics that influence the SEUROP system classification for Czech fleckvieh and Holstein bull carcasses

    Directory of Open Access Journals (Sweden)

    Radek Filipčík

    2006-01-01

    Full Text Available The aim of this work was to analyse the influence of certain characteristics (aptitude, age, carcass weight, net daily gain, feeding on the final carcass classification in the SEUROP system. 703 Czech Fleckvieh bulls and 642 Holstein bulls were studied. The animals were slaughtered and evaluated at a designated beef processing company. Combine aptitude carcasses shown significant differences between characteristics. Remarkable differences of group averages (P>0, 01 were established between farms and they were due to various rearing conditions. Also the levels of net daily gain between aptitudes were proved significantly. Holstein breed showed significant difference among The net daily gain < 500 g.day–1 and levels 551–600; 601–650 and above 651 g.day–1. The SEUROP system is influenced the most by the feeding regime, which is described by a net daily gain in this work, and farm impact.

  19. The 'antisocial' person: an insight in to biology, classification and current evidence on treatment

    Directory of Open Access Journals (Sweden)

    Rajapakse Senaka

    2010-07-01

    Full Text Available Abstract Background This review analyses and summarises the recent advances in understanding the neurobiology of violence and empathy, taxonomical issues on defining personality disorders characterised by disregard for social norms, evidence for efficacy of different treatment modalities and ethical implications in defining 'at-risk' individuals for preventive interventions. Methods PubMed was searched with the keywords 'antisocial personality disorder', 'dissocial personality disorder' and 'psychopathy'. The search was limited to articles published in English over the last 10 years (1999 to 2009 Results Both diagnostic manuals used in modern psychiatry, the Diagnostic and Statistical Manual published by the American Psychiatric Association and the International Classification of Diseases published by the World Health Organization, identify a personality disorder sharing similar traits. It is termed antisocial personality disorder in the diagnostic and statistical manual and dissocial personality disorder in the International Classification of Diseases. However, some authors query the ability of the existing manuals to identify a special category termed 'psychopathy', which in their opinion deserves special attention. On treatment-related issues, many psychological and behavioural therapies have shown success rates ranging from 25% to 62% in different cohorts. Multisystemic therapy and cognitive behaviour therapy have been proven efficacious in many trials. There is no substantial evidence for the efficacy of pharmacological therapy. Currently, the emphasis is on early identification and prevention of antisocial behaviour despite the ethical implications of defining at-risk children. Conclusions Further research is needed in the areas of neuroendocrinological associations of violent behaviour, taxonomic existence of psychopathy and efficacy of treatment modalities.

  20. Research activities: magic bullet and all that

    International Nuclear Information System (INIS)

    Basten, Tony.

    1990-01-01

    The Centenary Institute of Cancer Medicine and Cell Biology is the brain-child of the University of Sydney and its campus teaching hospital, Royal Prince Alfred. At present its research portfolio includes studies of cancer, autoimmune diseases like rheumatoid arthritis or multiple sclerosis (in which white cells or antibodies attack our own tissues), and certain infections diseases, including leprosy and AIDS. Experiments involving radioactively labelled monoclonal antibodies in immunological and molecular biology studies are briefly presented. ills

  1. Laparoscopic Bullet Removal in a Penetrating Abdominal Gunshot

    Directory of Open Access Journals (Sweden)

    Christos Stefanou

    2016-01-01

    Full Text Available Penetrating abdominal trauma has been traditionally treated by exploratory laparotomy. Nowadays laparoscopy has become an accepted practice in hemodynamically stable patient without signs of peritonitis. We report a case of a lower anterior abdominal gunshot patient treated laparoscopically. A 32-year-old male presented to the Emergency Department with complaint of gunshot penetrating injury at left lower anterior abdominal wall. The patient had no symptoms or obvious bleeding and was vitally stable. On examination we identified 1 cm diameter entry wound at the left lower abdominal wall. The imaging studies showed the bullet in the peritoneal cavity but no injured intraperitoneal and retroperitoneal viscera. We decided to remove the bullet laparoscopically. Twenty-four hours after the intervention the patient was discharged. The decision for managing gunshot patients should be based on clinical and diagnostic findings. Anterior abdominal injuries in a stable patient without other health problems can be managed laparoscopically.

  2. Diet-derived microRNAs: unicorn or silver bullet?

    Science.gov (United States)

    Witwer, Kenneth W; Zhang, Chen-Yu

    2017-01-01

    In ancient lore, a bullet cast from silver is the only effective weapon against monsters. The uptake of active diet-derived microRNAs (miRNAs) in consumers may be the silver bullet long sought after in nutrition and oral therapeutics. However, the majority of scientists consider the transfer and regulation of consumer's gene activity by these diet-derived miRNAs to be a fantasy akin to spotting a unicorn. Nevertheless, groups like Dr. Chen-Yu Zhang's lab in Nanjing University have stockpiled breathtaking amounts of data to shoot down these naysayers. Meanwhile, Dr. Ken Witwer at John Hopkins has steadfastly cautioned the field to beware of fallacies caused by contamination, technical artifacts, and confirmation bias. Here, Dr. Witwer and Dr. Zhang share their realities of dietary miRNAs by answering five questions related to this controversial field.

  3. Lead poisoning from retained bullets: pathogenesis, diagnosis, and management

    International Nuclear Information System (INIS)

    Linden, M.A.; Manton, W.I.; Stewart, R.M.; Thal, E.R.; Feit, H.

    1982-01-01

    Lead intoxication (plumbism) from retained bullets has rarely been reported but may be fatal if unrecognized. Bullets lodged within joint spaces or pseudocysts are more likely to develop this complication, although patients with retained missiles in other locations may also be at risk. Subtle findings such as the occurrence of unexplained anemia, abdominal colic, nephropathy, or neurologic deterioration in patients with retained missiles may suggest consideration of plumbism. An intercurrent metabolic stress such as infection, endocrinopathy, or alcoholism may be a precipitating factor. Among the various diagnostic studies available, mass spectrometric stable isotope dilution analysis may be the most reliable. It is important to employ chelation therapy prior to any operative intervention. This will reduce the mobilization of lead from bone during or following the surgical procedure

  4. Bullet Trap Feasibility Assessment and Implementation Plan. (Technology Identification).

    Science.gov (United States)

    1996-03-01

    paralisis of of lead objects or its peripherical nerves and, in compounds (parasiticides, some cases, death. dyes , mordants , polyvinyl- To a correct...impact of the projectiles. In addition, bullet traps reduce or eliminate safety problems caused by ricochets off natural or other materials on current...rubber granules canted back at a natural angle of repose. Underneath this large pile of rubber granules is a conveyor belt and support structure. Behind

  5. ''Heavy light bullets'' in electron-positron plasma

    International Nuclear Information System (INIS)

    Berezhiani, V.I.; Mahajan, S.M.

    1995-03-01

    The nonlinear propagation of circularly polarized electromagnetic waves with relativistically strong amplitudes in an unmagnetized hot electron-positron plasma with a small fraction of ions is investigated. The possibility of finding localized solutions in such a plasma is explored. It is shown that these plasmas support the propagation of ''heavy light bullets''; nondiffracting and nondispersive electromagnetic (EM) pulses with large density bunching. (author). 24 refs, 12 figs

  6. Interaction of Interstellar Shocks with Dense Obstacles: Formation of ``Bullets''

    Science.gov (United States)

    Gvaramadze, V. V.

    The so-called cumulative effect take place in converging conical shock waves arising behind dense obstacles overtaken by incident interstellar shock. A significant part of energy of converging flow of matter swept-up by a radiative conical shock can be transferred to a dense jet-like ejection (``bullet'') directed along the cone axis. Possible applications of this effect for star-forming regions (e.g., OMC-1) and supernova remnants (e.g., Vela SNR) are discussed.

  7. Targeting the latest hallmark of cancer: another attempt at 'magic bullet' drugs targeting cancers' metabolic phenotype.

    Science.gov (United States)

    Cuperlovic-Culf, M; Culf, A S; Touaibia, M; Lefort, N

    2012-10-01

    The metabolism of tumors is remarkably different from the metabolism of corresponding normal cells and tissues. Metabolic alterations are initiated by oncogenes and are required for malignant transformation, allowing cancer cells to resist some cell death signals while producing energy and fulfilling their biosynthetic needs with limiting resources. The distinct metabolic phenotype of cancers provides an interesting avenue for treatment, potentially with minimal side effects. As many cancers show similar metabolic characteristics, drugs targeting the cancer metabolic phenotype are, perhaps optimistically, expected to be 'magic bullet' treatments. Over the last few years there have been a number of potential drugs developed to specifically target cancer metabolism. Several of these drugs are currently in clinical and preclinical trials. This review outlines examples of drugs developed for different targets of significance to cancer metabolism, with a focus on small molecule leads, chemical biology and clinical results for these drugs.

  8. Oral lead bullet fragment exposure in northern bobwhite (Colinus virginianus).

    Science.gov (United States)

    Kerr, Richard; Holladay, Jeremy; Holladay, Steven; Tannenbaum, Lawrence; Selcer, Barbara; Meldrum, Blair; Williams, Susan; Jarrett, Timothy; Gogal, Robert

    2011-11-01

    Lead (Pb) is a worldwide environmental contaminant known to adversely affect multiple organ systems in both mammalian and avian species. In birds, a common route of exposure is via oral ingestion of lead particles. Data are currently lacking for the retention and clearance of Pb bullet fragments in gastrointestinal (GI) tract of birds while linking toxicity with blood Pb levels. In the present study, northern bobwhite quail fed a seed-based diet were orally gavaged with Pb bullet fragments (zero, one or five fragments/bird) and evaluated for rate of fragment clearance, and changes in peripheral blood, renal, immune, and gastrointestinal parameters. Based on radiographs, the majority of the birds cleared or absorbed the fragments by seven days, with the exception of one five-fragment bird which took between 7 and 14 days. Blood Pb levels were higher in males than females, which may be related to egg production in females. In males but not females, feed consumption, body weight gain, packed cell volume (PCV), plasma protein concentration, and δ-aminolevulinic acid dehydratase (δ-ALAD) activity were all adversely affected by five Pb fragments. Birds of both sexes that received a single Pb fragment displayed depressed δ-ALAD, suggesting altered hematologic function, while all birds dosed with five bullet fragments exhibited greater morbidity.

  9. A Measuring Method About the Bullet Velocity in Electromagnetic Rail Gun

    Directory of Open Access Journals (Sweden)

    Jianming LIU

    2014-02-01

    Full Text Available The operating principle of electromagnetic rail gun by store capacitor was analyzed. A simulation model about the bullet velocity in the electromagnetic rail gun was built. The results of computer simulation experiment showed the relationships between the bullet velocity and the capacitor charging voltage and the pellet mass. By ten coil targets, a new kind of measuring method for the bullet velocity in electromagnetic rail gun was presented. The results of the actual experiment were analyzed. The improving method for measuring bullet velocity was put forward.

  10. Nanobody: the "magic bullet" for molecular imaging?

    Science.gov (United States)

    Chakravarty, Rubel; Goel, Shreya; Cai, Weibo

    2014-01-01

    Molecular imaging involves the non-invasive investigation of biological processes in vivo at the cellular and molecular level, which can play diverse roles in better understanding and treatment of various diseases. Recently, single domain antigen-binding fragments known as 'nanobodies' were bioengineered and tested for molecular imaging applications. Small molecular size (~15 kDa) and suitable configuration of the complementarity determining regions (CDRs) of nanobodies offer many desirable features suitable for imaging applications, such as rapid targeting and fast blood clearance, high solubility, high stability, easy cloning, modular nature, and the capability of binding to cavities and difficult-to-access antigens. Using nanobody-based probes, several imaging techniques such as radionuclide-based, optical and ultrasound have been employed for visualization of target expression in various disease models. This review summarizes the recent developments in the use of nanobody-based probes for molecular imaging applications. The preclinical data reported to date are quite promising, and it is expected that nanobody-based molecular imaging agents will play an important role in the diagnosis and management of various diseases.

  11. The density and velocity of plasma bullets propagating along one dielectric tube

    Directory of Open Access Journals (Sweden)

    Longfei Ji

    2015-08-01

    Full Text Available This study shows that the propagation of plasma bullets along one dielectric tube is strongly affected by many discharge parameters, such as the waveform of applied voltage (AC or pulsed DC, peak voltage, He flow rate, and the frequency of AC voltage. Analysis indicates that the density and velocity of plasma bullets are mainly determined by the electric field at the front of plasma bullets. These discharge parameters may significantly influence the distribution of plasma potential along the tube, thus control the electric field at the front of plasma bullets and their propagation. An increase in the pulsed DC voltage with its rise time of <40-50 ns can lead to an obvious improvement in the electric field at the front of plasma bullets, resulting in generation of a plasma in the high density gas and a fast propagation of plasma bullets. He flowing through the tube can contribute to the surface diffusion of charged species, and greatly increase the electric field at the front of plasma bullets. During the propagation of plasma bullets, their density is decreased due to the surface recombination of charged species, such as electrons and ions.

  12. [The forensic medical characteristics of the entrance bullet holes created by the shots from pneumatic rifles].

    Science.gov (United States)

    Legin, G A; Bondarchuk, A O; Perebetjuk, A N

    2015-01-01

    The objective of the present study was to compare the injurious action of three types of the bullets for the pneumatic weapons shot from different distances using the Gamo pump air pistol and the BAM B22-1 pneumatic rifle. The following four kinds of the bullets were tested: "the fireball", "Luman cap 0.3", "Luman Field Target 0.68" and "DIABOLO". It was experimentally shown that the injurious action of the bullets fired from the same distance from the pneumatic weapons depends on the type of both the bullet and the weapon, as well as the properties of the target material. Specifically, the action of bullets fired from the piston pneumatic rifle remained stable whereas that of the bullets shot from the gas-balloon air pistol decreased as the gas was exhausted. The studies by the contact-diffusion method have demonstrated that the entrance bullet holes created by the shots from pneumatic weapons are surrounded by dispersed metal particles which makes it possible to estimate the shooting distance. Moreover, the bullets fired from the pneumatic weapons leave the muzzle face imprint on certain target materials.

  13. Intra-myocardial Bullet causing heart block in a patient with multiple ...

    African Journals Online (AJOL)

    consolidation and bullet lodged above the diaphragm. The chest radiograph showed bullet lodged above the diaphragm. ARDS resolved markedly over the following. 7 days. However, there were persistent bronchial breath sounds in the left lower lung with purulent secretions and collapse with consolidation. CT scan of the ...

  14. Plasma bullet current measurements in a free-stream helium capillary jet

    Science.gov (United States)

    Oh, Jun-Seok; Walsh, James L.; Bradley, James W.

    2012-06-01

    A commercial current monitor has been used to measure the current associated with plasma bullets created in both the positive and negative half cycles of the sinusoidal driving voltage sustaining a plasma jet. The maximum values of the positive bullet current are typically ˜750 µA and persist for 10 µs, while the peaks in the negative current of several hundred μA are broad, persisting for about 40 µs. From the time delay of the current peaks with increasing distance from the jet nozzle, an average bullet propagation speed has been measured; the positive and negative bullets travel at 17.5 km s-1 and 3.9 km s-1 respectively. The net space charge associated with the bullet(s) has also been calculated; the positive and negative bullets contain a similar net charge of the order of 10-9 C measured at all monitor positions, with estimated charged particle densities nb of ˜1010-1011 cm-3 in the bullet.

  15. Plasma bullet current measurements in a free-stream helium capillary jet

    International Nuclear Information System (INIS)

    Oh, Jun-Seok; Walsh, James L; Bradley, James W

    2012-01-01

    A commercial current monitor has been used to measure the current associated with plasma bullets created in both the positive and negative half cycles of the sinusoidal driving voltage sustaining a plasma jet. The maximum values of the positive bullet current are typically ∼750 µA and persist for 10 µs, while the peaks in the negative current of several hundred μA are broad, persisting for about 40 µs. From the time delay of the current peaks with increasing distance from the jet nozzle, an average bullet propagation speed has been measured; the positive and negative bullets travel at 17.5 km s −1 and 3.9 km s −1 respectively. The net space charge associated with the bullet(s) has also been calculated; the positive and negative bullets contain a similar net charge of the order of 10 −9 C measured at all monitor positions, with estimated charged particle densities n b of ∼10 10 –10 11 cm −3 in the bullet. (special)

  16. Electric field measurements on plasma bullets in N2 using four-wave mixing

    NARCIS (Netherlands)

    van der Schans, M.; Böhm, P.; Nijdam, S.; IJzerman, W.L.; Czarnetzki, U.

    2015-01-01

    Atmospheric pressure plasma jets driven by pulsed DC or kHz AC voltages typically consist of discrete guided ionisation waves called plasma bullets. In this work, the electric field of plasma bullets generated in a pulsed DC jet with N2 as feed gas is investigated. Electric field measurements in N2

  17. Learning game physics with Bullet Physics and OpenGL

    CERN Document Server

    Dickinson, Chris

    2013-01-01

    A comprehensive set of straight-forward, easy-to-follow tutorials in OpenGL and Bullet Physics that will teach you how modern game physics and 3D graphics work.If you're a beginner or intermediate programmer with a basic understanding of 3D mathematics, and you want a stronger foundation in 3D graphics and physics, then this book is perfect for you! You'll even learn some of the fundamental concepts in 3D mathematics and software design that lies beneath them both, discovering some techniques and tricks in graphics and physics that you can use in any game development project.

  18. Caffeine citrate - Is it a silver bullet in neonatology?

    Science.gov (United States)

    Shrestha, Bikash; Jawa, Gaurav

    2017-10-01

    Caffeine citrate is one of the most prescribed drug in the present day NICU for apnea. Its efficacy, tolerability, wide therapeutic index and safety margin has made it the drug of choice among the methylxanthines. Its therapeutic uses in apnea of prematurity, mechanical ventilation, bronchopulmonary dysplasia has made it a "silver bullet" in neonatology. However, there are still controversies surrounding this drug. This review is aimed to update the reader about the basic pharmacology, current therapeutic uses, adverse effects, controversies as well as present and future research of caffeine. Copyright © 2017. Published by Elsevier B.V.

  19. Determining tissue-lead levels in large game mammals harvested with lead bullets: human health concerns.

    Science.gov (United States)

    Tsuji, L J S; Wainman, B C; Jayasinghe, R K; VanSpronsen, E P; Liberda, E N

    2009-04-01

    Recently, the use of lead isotope ratios has definitively identified lead ammunition as a source of lead exposure for First Nations people, but the isotope ratios for lead pellets and bullets were indistinguishable. Thus, lead-contaminated meat from game harvested with lead bullets may also be contributing to the lead body burden; however, few studies have determined if lead bullet fragments are present in big game carcasses. We found elevated tissue-lead concentrations (up to 5,726.0 microg/g ww) in liver (5/9) and muscle (6/7) samples of big game harvested with lead bullets and radiographic evidence of lead fragments. Thus, we would advise that the tissue surrounding the wound channel be removed and discarded, as this tissue may be contaminated by lead bullet fragments.

  20. Classification of biological agents

    NARCIS (Netherlands)

    Klein MR; LIS; cib

    2012-01-01

    Deze rapportage omvat een inventarisatie van de problematiek rond de classificatie van biologische agentia, die ziekte bij de mens kunnen veroorzaken.

    De constatering is dat de Europese lijst met classificaties verouderd is en geactualiseerd en uitgebreid zou moeten worden. De lijst bevat

  1. Evaluation of machine learning algorithms for classification of primary biological aerosol using a new UV-LIF spectrometer

    Science.gov (United States)

    Ruske, Simon; Topping, David O.; Foot, Virginia E.; Kaye, Paul H.; Stanley, Warren R.; Crawford, Ian; Morse, Andrew P.; Gallagher, Martin W.

    2017-03-01

    Characterisation of bioaerosols has important implications within environment and public health sectors. Recent developments in ultraviolet light-induced fluorescence (UV-LIF) detectors such as the Wideband Integrated Bioaerosol Spectrometer (WIBS) and the newly introduced Multiparameter Bioaerosol Spectrometer (MBS) have allowed for the real-time collection of fluorescence, size and morphology measurements for the purpose of discriminating between bacteria, fungal spores and pollen.This new generation of instruments has enabled ever larger data sets to be compiled with the aim of studying more complex environments. In real world data sets, particularly those from an urban environment, the population may be dominated by non-biological fluorescent interferents, bringing into question the accuracy of measurements of quantities such as concentrations. It is therefore imperative that we validate the performance of different algorithms which can be used for the task of classification.For unsupervised learning we tested hierarchical agglomerative clustering with various different linkages. For supervised learning, 11 methods were tested, including decision trees, ensemble methods (random forests, gradient boosting and AdaBoost), two implementations for support vector machines (libsvm and liblinear) and Gaussian methods (Gaussian naïve Bayesian, quadratic and linear discriminant analysis, the k-nearest neighbours algorithm and artificial neural networks).The methods were applied to two different data sets produced using the new MBS, which provides multichannel UV-LIF fluorescence signatures for single airborne biological particles. The first data set contained mixed PSLs and the second contained a variety of laboratory-generated aerosol.Clustering in general performs slightly worse than the supervised learning methods, correctly classifying, at best, only 67. 6 and 91. 1 % for the two data sets respectively. For supervised learning the gradient boosting algorithm was

  2. Brown sequard syndrome following firearm injury with a bullet lodged in the upper cervical canal

    International Nuclear Information System (INIS)

    Brohi, S.R.; Brohi, Q.R.

    2008-01-01

    A case of stray bullet injury in a child is reported who presented with Brown-Sequard syndrome and CSF leak from the wound at the nape of neck. Patient was assessed by plain radiography and CT scans showing bullet lying in the cervical spinal canal under the C1 and C2 laminae. Laminectomy at C1/C2 level was done and bullet was carefully removed. Patient improved neurologically and CSF discharge stopped. The case report indicated the atypical neurological presentation and possibility of survival in high cervical spinal firearm injury. (author)

  3. Pure air-plasma bullets propagating inside microcapillaries and in ambient air

    KAUST Repository

    Lacoste, Deanna; Bourdon, Anne; Kuribara, Koichi; Urabe, Keiichiro; Stauss, Sven; Terashima, Kazuo

    2014-01-01

    This paper reports on the characterization of air-plasma bullets in microcapillary tubes and in ambient air, obtained without the use of inert or noble gases. The bullets were produced by nanosecond repetitively pulsed discharges, applied in a dielectric barrier discharge configuration. The anode was a tungsten wire with a diameter of 50 μm, centered in the microcapillary, while the cathode was a silver ring, fixed on the outer surface of the fused silica tube. The effects of the applied voltage and the inner diameter of the microcapillary tube on the plasma behavior were investigated. Inside the tubes, while the topology of the bullets seems to be strongly dependent on the diameter, their velocity is only a function of the amplitude of the applied voltage. In ambient air, the propagation of air bullets with a velocity of about 1.25 ×105 m s-1 is observed.

  4. Effects of human decomposition on test fired bullet – An experimental research

    Directory of Open Access Journals (Sweden)

    Dinesh Rao

    2016-03-01

    The observations through comparison microscope indicated that the individual characteristic (microscopic markings on the bullet in the form of microstriae showed complete corrosion or obscuring by the 10th day. The surface appeared smooth, onset of corrosion process was noted on the 2nd day and by the 4th day 50% obscuring of the marks was noted. This change in the markings of the metal surface of the bullet was uniform to all the ammunitions used in this study. The control bullets showed no such changes during the period of study. The study confirms the existence of a potential danger in dealing with crime bullets retrieved from putrefied bodies. It also highlights the importance of early retrieval of dead bodies in firearm deaths and the importance of proper storage facilities to deal with cases of firearm deaths.

  5. Pure air-plasma bullets propagating inside microcapillaries and in ambient air

    KAUST Repository

    Lacoste, Deanna

    2014-11-04

    This paper reports on the characterization of air-plasma bullets in microcapillary tubes and in ambient air, obtained without the use of inert or noble gases. The bullets were produced by nanosecond repetitively pulsed discharges, applied in a dielectric barrier discharge configuration. The anode was a tungsten wire with a diameter of 50 μm, centered in the microcapillary, while the cathode was a silver ring, fixed on the outer surface of the fused silica tube. The effects of the applied voltage and the inner diameter of the microcapillary tube on the plasma behavior were investigated. Inside the tubes, while the topology of the bullets seems to be strongly dependent on the diameter, their velocity is only a function of the amplitude of the applied voltage. In ambient air, the propagation of air bullets with a velocity of about 1.25 ×105 m s-1 is observed.

  6. Endoscopic Removal of a Bullet That Migrated to the Third Ventricle Causing Hydrocephalus.

    Science.gov (United States)

    Aydoseli, Aydın; Unal, Tugrul Cem; Aras, Yavuz; Sabanci, Pulat Akın; Altunrende, Emre; Izgi, Nail

    2017-09-01

    Hydrocephalus caused by an intraventricular bullet is a rare event. We report a case of endoscopic removal of an intraventricular bullet. A 66-year-old man was admitted with a gunshot wound to the head after a suicide attempt. The bullet migrated from the frontal parenchyma to the third ventricle day 4 of admission. On day 21 of admission, the patient developed hydrocephalus with obstruction of the cerebral aqueduct. The bullet was accessed through an endoscopic third ventriculostomy and removed using an endoscope. Hydrocephalus may develop in patients with intraventricular foreign objects. When such objects must be removed, the endoscopic approach is a safe, efficient, and minimally invasive procedure. To our knowledge, this is the first case in the literature of foreign object removal from the ventricle via a transcortical endoscopic approach. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Formation of hydroxyl radical (sm-bulletOH) in illuminated surface waters contaminated with acidic mine drainage

    International Nuclear Information System (INIS)

    Allen, J.M.; Lucas, S.; Allen, S.K.

    1996-01-01

    Formation rates and steady-state concentrations of hydroxyl radical ( sm-bullet OH) in illuminated surface water samples collected in west-central Indiana that receive acidic mine drainage runoff are reported. Formation rates for sm-bullet OH in samples were measured by the addition of 1 x 10 -3 M benzene prior to illuminate in order to effectively scavenge all of the sm-bullet OH formed, thereby yielding phenol. The sm-bullet OH formation rates were calculated from the measured phenol formation rates. Steady-state concentrations of sm-bullet OH were measured by the addition of 5 x 10 -7 M nitrobenzene to the samples prior to illumination. Estimated sunlight sm-bullet OH formation rates range from 16 microM h -1 to 265 microM h -1 . Estimated sunlight steady-state sm-bullet OH concentrations range from 6.7 x 10 -15 to 4.0 x 10 -12 M. Both the formation rates and steady-state concentrations for sm-bullet OH are thus two to three orders of magnitude higher than values reported in the literature for other sunlit surface water samples. Due to the very high rates of formation and steady-state concentrations for sm-bullet OH in these samples, the authors conclude that aqueous-phase reactions involving sm-bullet OH represent a significant pathway by which organic pollutants in illuminated surface waters receiving acidic mine drainage runoff may be consumed

  8. 18 GHz SZ Measurements of the Bullet Cluster Siddharth S. Malu ...

    Indian Academy of Sciences (India)

    1E0657-56, known as the 'Bullet cluster', is one of the hottest known clusters. It is a cluster collision/merger event at z ∼0.296, with the larger, westward cluster being ∼10 times the mass of the smaller 'bullet'. It is known to have a strong radio halo (Liang et al. 2000), and the Sunyaev–Zel'dovich effect (Andreani et al. 1999;.

  9. Radiolabelled monoclonal antibodies: magic bullets for colorectal carcinoma

    International Nuclear Information System (INIS)

    Slade, Linda

    1997-01-01

    Radiolabelled monoclonal antibodies (MoAbs) have been heralded as highly specific detection agents for many types of tumours. However, because of the many problems that have been associated with the use of these agents, their development and successes did not meet expectations. This paper discusses the use of radiolabelled MoAbs in the diagnosis and staging of colorectal cancer, the type of antibodies and radionuclides investigated over the past thirty years, and the advantages and disadvantages of each. An attempt is made to define the role of radioimmunoscintigraphy (RIS) in the investigation and management of patients with colorectal cancer. It appears that this technique can improve tumour detection, especially when used in conjunction with other imaging modalities. High sensitivities and specificities have been found using radio-labelled MoAbs for investigation of colorectal carcinoma. However, the author estimates there are a number of areas that require further research and improvement before naming radiolabelled MoAbs as 'magic bullets' for colorectal cancer. 8 refs., 3 tabs

  10. Fractures Due to Gunshot Wounds: Do Retained Bullet Fragments Affect Union?

    Science.gov (United States)

    Riehl, John T; Connolly, Keith; Haidukewych, George; Koval, Ken

    2015-01-01

    Many types of projectiles, including modern hollow point bullets, fragment into smaller pieces upon impact, particularly when striking bone. This study was performed to examine the effect on time to union with retained bullet material near a fracture site in cases of gunshot injury. All gunshot injuries operatively treated with internal fixation at a Level 1 Trauma Center between March 2008 and August 2011 were retrospectively reviewed. Retained bullet load near the fracture site was calculated based on percentage of material retained compared to the cortical diameter of the involved bone. Analyses were performed to assess the effect of the lead-cortical ratio and amount of comminution on time to fracture union. Thirty-two patients (34 fractures) met the inclusion criteria, with an equal number of comminuted (17) and non-comminuted fractures (17). Seventeen of 34 fractures (50%) united within 4 months, 16/34 (47%) developed a delayed union, and 1/34 (3%) developed a nonunion requiring revision surgery. Sixteen of 17 fractures (94%) that united by 4 months had a cumulative amount of bullet fragmentation retained near the fracture site of less than 20% of the cortical diameter. Nine out of 10 fractures (90%) with retained fragments near the fracture site was equal to or exceeding 20% of the cortical diameter had delayed or nonunion. Fracture comminution had no effect on time to union. The quantity of retained bullet material near the fracture site was more predictive of the rate of fracture union than was comminution. Fractures with bullet fragmentation equal to or exceeding 20% of the cortical width demonstrated a significantly higher rate of delayed union/nonunion compared to those fractures with less retained bullet material, which may indicate a local cytotoxic effect from lead on bone healing. These findings may influence decisions on timing of secondary surgeries. Level III.

  11. Quantitative/Statistical Approach to Bullet-to-Firearm Identification with Consecutively Manufactured Barrels

    Energy Technology Data Exchange (ETDEWEB)

    Peter Striupaitis; R.E. Gaensslen

    2005-01-30

    Efforts to use objective image comparison and bullet scanning technologies to distinguish bullets from consecutively manufactured handgun barrels from two manufacturers gave mixed results. The ability of a technology to reliably distinguish between matching and non-matching bullets, where the non-matching bullets were as close in pattern to the matching ones as is probably possible, would provide evidence that the distinctions could be made ''objectively'', and independently of human eyes. That evidence is identical or very close to what seems to be needed to satisfy Daubert standards. It is fair to say that the FTI IBIS image comparison technology correctly distinguished between all the Springfield barrel bullets, and between most but not all of the HiPoint barrel bullets. In the HiPoint cases that were not distinguished 100% of the time, they would he distinguished correctly at least 83% of the time. These results, although obviously limited to the materials used in the comparisons, provide strong evidence that barrel-to-bullet matching is objectively reliable. The results with SciClops were less compelling. The results do not mean that bullet-to-barrel matching is not objectively reliable--rather, they mean that this version of the particular technology could not quite distinguish between these extremely similar yet different bullets as well as the image comparison technology did. In a number of cases, the numerical results made the correct distinctions, although they were close to one another. It is hard to say from this data that this technology differs in its ability to make distinctions between the manufacturers, because the results are very similar with both. The human examiner results were as expected. We did not expect any misidentifications, and there were not any. It would have been preferable to have a higher return rate, and thus more comparisons in the overall sample. As noted, the ''consecutively manufactured barrel

  12. China's bullet trains facilitate market integration and mitigate the cost of megacity growth.

    Science.gov (United States)

    Zheng, Siqi; Kahn, Matthew E

    2013-04-02

    Megacity growth in the developing world is fueled by a desire to access their large local labor markets. Growing megacities suffer from high levels of traffic congestion and pollution, which degrade local quality of life. Transportation technology that allows individuals to access the megacity without living within its boundaries offers potentially large social benefits, because individuals can enjoy the benefits of urban agglomeration while not paying megacity real estate rents and suffering from the city's social costs. This paper presents evidence supporting the claim that China's bullet trains are playing this role. The bullet train is regarded as one of the most significant technological breakthroughs in passenger transportation developed in the second half of the 20th century. Starting in 2007, China has introduced several new bullet trains that connect megacities such as Beijing, Shanghai, and Guangzhou with nearby cities. Through facilitating market integration, bullet trains will stimulate the development of second- and third-tier cities. By offering households and firms a larger menu of location alternatives, bullet trains help to protect the quality of life of the growing urban population. We document that this transport innovation is associated with rising real estate prices in the nearby secondary cities.

  13. Development of a biosensor protein bullet as a fluorescent method for fast detection of Escherichia coli in drinking water.

    Directory of Open Access Journals (Sweden)

    Ignacio Gutiérrez-Del-Río

    Full Text Available Drinking water can be exposed to different biological contaminants from the source, through the pipelines, until reaching the final consumer or industry. Some of these are pathogenic bacteria and viruses which may cause important gastrointestinal or systemic diseases. The microbiological quality of drinking water relies mainly in monitoring three indicator bacteria of faecal origin, Escherichia coli, Enterococcus faecalis and Clostridium perfringens, which serve as early sentinels of potential health hazards for the population. Here we describe the analysis of three chimeric fluorescent protein bullets as biosensor candidates for fast detection of E. coli in drinking water. Two of the chimeric proteins (based on GFP-hadrurin and GFP-pb5 chimera proteins failed with respect to specificity and/or sensitivity, but the GFP-colS4 chimera protein was able to carry out specific detection of E. coli in drinking water samples in a procedure encompassing about 8 min for final result and this biosensor protein was able to detect in a linear way between 20 and 103 CFU of this bacterium. Below 20 CFU, the system cannot differentiate presence or absence of the target bacterium. The fluorescence in this biosensor system is provided by the GFP subunit of the chimeric protein, which, in the case of the better performing sensor bullet, GFP-colS4 chimera, is covalently bound to a flexible peptide bridge and to a bacteriocin binding specifically to E. coli cells. Once bound to the target bacteria, the excitation step with 395 nm LED light causes emission of fluorescence from the GFP domain, which is amplified in a photomultiplier tube, and finally this signal is converted into an output voltage which can be associated with a CFU value and these data distributed along mobile phone networks, for example. This method, and the portable fluorimeter which has been developed for it, may contribute to reduce the analysis time for detecting E. coli presence in drinking

  14. Development of a biosensor protein bullet as a fluorescent method for fast detection of Escherichia coli in drinking water.

    Science.gov (United States)

    Gutiérrez-Del-Río, Ignacio; Marín, Laura; Fernández, Javier; Álvarez San Millán, María; Ferrero, Francisco Javier; Valledor, Marta; Campo, Juan Carlos; Cobián, Natalia; Méndez, Ignacio; Lombó, Felipe

    2018-01-01

    Drinking water can be exposed to different biological contaminants from the source, through the pipelines, until reaching the final consumer or industry. Some of these are pathogenic bacteria and viruses which may cause important gastrointestinal or systemic diseases. The microbiological quality of drinking water relies mainly in monitoring three indicator bacteria of faecal origin, Escherichia coli, Enterococcus faecalis and Clostridium perfringens, which serve as early sentinels of potential health hazards for the population. Here we describe the analysis of three chimeric fluorescent protein bullets as biosensor candidates for fast detection of E. coli in drinking water. Two of the chimeric proteins (based on GFP-hadrurin and GFP-pb5 chimera proteins) failed with respect to specificity and/or sensitivity, but the GFP-colS4 chimera protein was able to carry out specific detection of E. coli in drinking water samples in a procedure encompassing about 8 min for final result and this biosensor protein was able to detect in a linear way between 20 and 103 CFU of this bacterium. Below 20 CFU, the system cannot differentiate presence or absence of the target bacterium. The fluorescence in this biosensor system is provided by the GFP subunit of the chimeric protein, which, in the case of the better performing sensor bullet, GFP-colS4 chimera, is covalently bound to a flexible peptide bridge and to a bacteriocin binding specifically to E. coli cells. Once bound to the target bacteria, the excitation step with 395 nm LED light causes emission of fluorescence from the GFP domain, which is amplified in a photomultiplier tube, and finally this signal is converted into an output voltage which can be associated with a CFU value and these data distributed along mobile phone networks, for example. This method, and the portable fluorimeter which has been developed for it, may contribute to reduce the analysis time for detecting E. coli presence in drinking water.

  15. Stunning effect of different rifle-bullets for slaughter of outdoor cattle

    Directory of Open Access Journals (Sweden)

    Stefanie Retz

    2014-12-01

    Full Text Available The slaughter method via gunshot implies a stunning of cattle by means of a targeted shot from a rifle and is as an alternative to regular slaughter at abattoirs. This method is only permitted under restricted circumstances and if the cattle is held on a pasture all the year. However, there is a considerable lack of specifications regulated by law concerning calibre and bullet-type. In this study, four different calibres, two bullet-types and two different shot placements were investigated with respect to their stunning efficiency. All of the calibres exhibited an entry-energy over 400 J and provided sufficient stunning potential. Yet, only calibre .22 Magnum caused no exit of the bullet out of the scull, which provides higher safety conditions for man and cattle.

  16. Gunshot Wound in Lumbar Spine with Intradural Location of a Bullet

    Directory of Open Access Journals (Sweden)

    G. Bordon

    2014-01-01

    Full Text Available The presence of a migratory bullet in the spinal canal after a gunshot injury is a rare finding, specially without causing permanent neurologic damage. We present the case of a patient who suffered a gunshot wound with an entry point in the posterior arc of L2-L3 and a migratory bullet detected at the level of L5-S1 in the CT scan. The patient complained about intense headache, dizziness, and variable sensitive impairment in lower legs apparently depending on the patient’s position in bed. We decided to remove the bullet in order to prevent the delayed neurological damage and lead toxicity. We discuss technical details of this surgery.

  17. Lead poisoning due to gunshot bullet in contact with cerebrospinal fluid: case report

    Directory of Open Access Journals (Sweden)

    Paulo Roberto de Madureira

    Full Text Available CONTEXT: Lead poisoning due to retained gunshot bullets is a well-known clinical problem that is fairly frequently described in the literature. The risk factors for this occurrence relate mainly to whether the lead bullet is in contact with the joint fluid or cerebrospinal fluid (CSF. The treatment for these cases entails chelation therapy while symptoms are shown and definitive surgical removal of the bullet as a potential source of lead. The aim of this paper is to describe a clinical case of lead poisoning due to a retained gunshot bullet in contact with CSF. CASE REPORT: A 42-year-old male was hit by gunshot bullets during a holdup, and one of them was retained in the spinal cord. Six years later, he developed intense low back pain and underwent laminectomy. Nine years later, he then underwent arthrodesis on L5-S1, but he developed intense abdominal pain after the surgical procedure. For five years, he was treated with calcium versenate in five-day cycles, with a good response. The chelation therapy cycles showed great efficacy during symptomatic periods, thus reducing the symptoms and signs of poisoning and promoting great amounts of lead excretion, thereby reducing the total lead burden responsible for the symptoms. Fortunately, over the last four years, the symptoms have improved and the urine levels of aminolevulinic acid (ALA have declined, to reach complete normalization. This shows that a healing process is probably taking place on the spinal wound, thereby isolating the bullet fragments from CSF contact.

  18. A call for a standard classification system for future biologic research: the rationale for new PRP nomenclature.

    Science.gov (United States)

    Mautner, Kenneth; Malanga, Gerard A; Smith, Jay; Shiple, Brian; Ibrahim, Victor; Sampson, Steven; Bowen, Jay E

    2015-04-01

    Autologous cell therapies including platelet-rich plasma (PRP) and bone marrow concentrate (BMC) are increasingly popular options for soft tissue and joint-related diseases. Despite increased clinical application, conflicting research has been published regarding the efficacy of PRP, and few clinical publications pertaining to BMC are available. Preparations of PRP (and BMC) can vary in many areas, including platelet concentration, number of white blood cells, presence or absence of red blood cells, and activation status of the preparation. The potential effect of PRP characteristics on PRP efficacy is often not well understood by the treating clinician, and PRP characteristics, as well as the volume of PRP delivered, are unfortunately not included in the methods of many published research articles. It is essential to establish a standard reporting system for PRP that facilitates communication and the interpretation and synthesis of scientific investigations. Herein, the authors propose a new PRP classification system reflecting important PRP characteristics based on contemporary literature and recommend adoption of minimal standards for PRP reporting in scientific investigations. Widespread adoption of these recommendations will facilitate interpretation and comparison of clinical studies and promote scientifically based progress in the field of regenerative medicine. Copyright © 2015 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  19. Characteristics of behind armor blunt trauma produced by bullets with different structural materials: an experimental study

    Directory of Open Access Journals (Sweden)

    Ling-qing WANG

    2013-07-01

    Full Text Available Objective To investigate the effect of structural materials of bullets on behind armor blunt trauma (BABT. Methods Ten healthy male Landraces were randomly divided into two groups (5 each: 56 type 7.62-mm rifle bullet group and SS109 5.56-mm rifle bullet group. The kinetic energy of two types of bullets was adjusted to the same level (about 1880J by the way of grow downwards gunpowder. Then the animals as protected with both grade NIJ Ⅲ ceramic hard armor and grade Ⅱ police soft body armor, were shot at the left midclavicular line of fourth intercostal space (shooting distance was 25m. The damage to the animals was observed. Other 2 healthy male Landraces were selected, and biomechanical sensor was subcutaneously implanted into the soft tissue in precordium and intracalvarium to detect the pressure at the time point of bullet contact under the protection of armor, and the relationship between pressure and damage was analyzed. Results Respiration, heart rate and systolic arterial pressure of animals in two groups were all elevated after injury, but there was no significant difference between the two groups. No obvious change was found on blood oxygen saturation of both groups. Gross anatomy showed the predominant local injury was cardiac and pulmonary contusions. The area of pulmonary hemorrhage of 7.62mm group was 6.00%±3.18%, significantly higher than that of 5.56mm group (3.59%±2.11%, P<0.05. Histopathological examination revealed acute injuries of lung tissues, myocardial tissue and cerebral cortical neurons. The contents of cardiac troponin T (TnT, creatine kinase (CK and creatine kinase-MB (CK-MB isoenzyme were all increased 3 hours after injury, and the rise was higher in 7.62mm group than in 5.56mm group (P<0.05. Biomechanical testing showed the pressure of precordium and intracalvarium was elevated at the moment of bullet contact, and the rise was higher in 7.62mm group than in 5.56mm group (P<0.05. Conclusions

  20. Analysis of Anti-Bullet Resistance of Armored Steels of Foreign Manufacture

    Directory of Open Access Journals (Sweden)

    V. N. Zuzov

    2017-01-01

    Full Text Available The paper studies penetrating armour plates from the steel alloys such as Armox 560T, Domex protect 500, Weldox 700 E, Hardox 400, and Armstal 500, which are used for armour protection. In all tests for five different thick (6 mm, 8 mm, 10 mm, 6 + 6 mm, and 8 + 8mm plates was used one of the most common bullets, i.e. a 7.62 mm "APM2" (hard steel core bullet with an impact velocity of 830 m / s and 920 m / s. The article presents the developed rational finite element models of plates and bullets, which allow us to obtain results with acceptable accuracy and minimum time of solution using the LS-DYNA solver. Predicts the rational thickness values and the steel properties to ensure protection according to the European standard EN1063 ("BR7". Also conducts analysis of influence of the friction coefficient on the results of numerical simulation.The main results of calculations include the residual velocity and kinetic energy of the bullet after penetrating and the pattern of the plate fracture mechanism (for each plate type and thickness. As a result of the studies, it was found that the monolayer 6 mm, 8 mm and 10 mm thick plates from all the investigated steel alloys do not provide a protection level of "BR7" (with an initial bullet velocity of 830 m / s and, on the other hand, the two-layer plates from the alloys Armox 560T, Domex protect 500, and Armstal 500 with a total thickness of 12 mm provide such level of protection. It was also revealed that the influence of the coefficient of friction on the resistance to the bullet penetration is very small, so friction can be neglected.At an initial velocity of 920 m / s a bullet penetrated two-layer 6x2 mm thick plates from all the steel alloys under consideration, while with a thickness of 8x2 mm the bullet could not penetrate (except the Weldox 700E alloy plate.

  1. Biological warfare warriors, secrecy and pure science in the Cold War: how to understand dialogue and the classifications of science.

    Science.gov (United States)

    Bud, Robert

    2014-01-01

    This paper uses a case study from the Cold War to reflect on the meaning at the time of the term 'Pure Science'. In 1961, four senior scientists from Britain's biological warfare centre at Porton Down visited Moscow both attending an International Congress and visiting Russian microbiological and biochemical laboratories. The reports of the British scientists in talking about a limited range of topics encountered in the Soviet Union expressed qualities of openness, sociologists of the time associated with pure science. The paper reflects on the discourses of "Pure Science", secrecy and security in the Cold War. Using Bakhtin's approach, I suggest the cordial communication between scientists from opposing sides can be seen in terms of the performance, or speaking, of one language among several at their disposal. Pure science was the language they were allowed to share outside their institutions, and indeed political blocs.

  2. Erythroleukemia shares biological features and outcome with myelodysplastic syndromes with excess blasts: a rationale for its inclusion into future classifications of myelodysplastic syndromes.

    Science.gov (United States)

    Calvo, Xavier; Arenillas, Leonor; Luño, Elisa; Senent, Leonor; Arnan, Montserrat; Ramos, Fernando; Ardanaz, María Teresa; Pedro, Carme; Tormo, Mar; Montoro, Julia; Díez-Campelo, María; Arrizabalaga, Beatriz; Xicoy, Blanca; Bonanad, Santiago; Jerez, Andrés; Nomdedeu, Benet; Ferrer, Ana; Sanz, Guillermo F; Florensa, Lourdes

    2016-12-01

    Erythroleukemia was considered an acute myeloid leukemia in the 2008 World Health Organization (WHO) classification and is defined by the presence of ≥50% bone marrow erythroblasts, having <20% bone marrow blasts from total nucleated cells but ≥20% bone marrow myeloblasts from nonerythroid cells. Erythroleukemia shares clinicopathologic features with myelodysplastic syndromes, especially with erythroid-predominant myelodysplastic syndromes (≥50% bone marrow erythroblasts). The upcoming WHO revision proposes to eliminate the nonerythroid blast cell count rule and to move erythroleukemia patients into the appropriate myelodysplastic syndrome category on the basis of the absolute blast cell count. We conducted a retrospective study of patients with de novo erythroleukemia and compared their clinico-biological features and outcome with those of de novo myelodysplastic syndromes, focusing on erythroid-predominant myelodysplastic syndromes. Median overall survival of 405 erythroid-predominant myelodysplastic syndromes without excess blasts was significantly longer than that observed in 57 erythroid-predominant refractory anemias with excess blasts-1 and in 59 erythroleukemias, but no significant difference was observed between erythroid-predominant refractory anemias with excess blasts-1 and erythroleukemias. In this subset of patients with ≥50% bone marrow erythroblasts and excess blasts, the presence of a high-risk karyotype defined by the International Prognostic Scoring System or by the Revised International Prognostic Scoring System was the main prognostic factor. In the same way, the survival of 459 refractory anemias with excess blasts-2, independently of having ≥20% bone marrow blasts from nonerythroid cells or not, was almost identical to the observed in 59 erythroleukemias. Interestingly, 11 low-blast count erythroleukemias with 5 to <10% bone marrow blasts from total nucleated cells showed similar survival than the rest of erythroleukemias. Our data

  3. Hypoxia in tumors: pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications.

    Science.gov (United States)

    Vaupel, Peter; Mayer, Arnulf

    2014-01-01

    Hypoxia is a hallmark of tumors leading to (mal-)adaptive processes, development of aggressive phenotypes and treatment resistance. Based on underlying mechanisms and their duration, two main types of hypoxia have been identified, coexisting with complex spatial and temporal heterogeneities. Chronic hypoxia is mainly caused by diffusion limitations due to enlarged diffusion distances and adverse diffusion geometries (e.g., concurrent vs. countercurrent microvessels, Krogh- vs. Hill-type diffusion geometry) and, to a lesser extent, by hypoxemia (e.g., in anemic patients, HbCO formation in heavy smokers), and a compromised perfusion or flow stop (e.g., due to disturbed Starling forces or intratumor solid stress). Acute hypoxia mainly results from transient disruptions in perfusion (e.g., vascular occlusion by cell aggregates), fluctuating red blood cell fluxes or short-term contractions of the interstitial matrix. In each of these hypoxia subtypes oxygen supply is critically reduced, but perfusion-dependent nutrient supply, waste removal, delivery of anticancer or diagnostic agents, and repair competence can be impaired or may not be affected. This detailed differentiation of tumor hypoxia may impact on our understanding of tumor biology and may aid in the development of novel treatment strategies, tumor detection by imaging and tumor targeting, and is thus of great clinical relevance.

  4. Lead isotope ratio analysis of bullet samples by using quadrupole ICP-MS

    International Nuclear Information System (INIS)

    Tamura, Shu-ichi; Hokura, Akiko; Nakai, Izumi; Oishi, Masahiro

    2006-01-01

    The measurement conditions for the precise analysis of the lead stable isotope ratio by using an ICP-MS equipped with a quadrupole mass spectrometer were studied in order to apply the technique to the forensic identification of bullet samples. The values of the relative standard deviation obtained for the ratio of 208 Pb/ 206 Pb, 207 Pb/ 206 Pb and 204 Pb/ 206 Pb were lower than 0.2% after optimization of the analytical conditions, including the optimum lead concentration of the sample solution to be about 70 ppb and an integration time for 1 m/s of 15 s. This method was applied to an analysis of lead in bullets for rifles and handguns; a stable isotope ratio of lead was found to be suitable for the identification of bullets. This study has demonstrated that the lead isotope ratio measured by using a quadrupole ICP-MS was useful for a practical analysis of bullet samples in forensic science. (author)

  5. Science Fair Projects. LC Science Tracer Bullet. TB 07-6

    Science.gov (United States)

    Howland, Joyce, Comp.

    2007-01-01

    Selected sources in this bibliography provide guidance to students, parents, and teachers throughout the process of planning, developing, implementing and competing in science fair activities. Sources range in suitability from elementary to high school levels. This guide updates "Library of Congress Science Tracer Bullet" 01-4. More specialized…

  6. Lead bullet fragments in venison from rifle-killed deer: potential for human dietary exposure.

    Directory of Open Access Journals (Sweden)

    W Grainger Hunt

    Full Text Available Human consumers of wildlife killed with lead ammunition may be exposed to health risks associated with lead ingestion. This hypothesis is based on published studies showing elevated blood lead concentrations in subsistence hunter populations, retention of ammunition residues in the tissues of hunter-killed animals, and systemic, cognitive, and behavioral disorders associated with human lead body burdens once considered safe. Our objective was to determine the incidence and bioavailability of lead bullet fragments in hunter-killed venison, a widely-eaten food among hunters and their families. We radiographed 30 eviscerated carcasses of White-tailed Deer (Odocoileus virginianus shot by hunters with standard lead-core, copper-jacketed bullets under normal hunting conditions. All carcasses showed metal fragments (geometric mean = 136 fragments, range = 15-409 and widespread fragment dispersion. We took each carcass to a separate meat processor and fluoroscopically scanned the resulting meat packages; fluoroscopy revealed metal fragments in the ground meat packages of 24 (80% of the 30 deer; 32% of 234 ground meat packages contained at least one fragment. Fragments were identified as lead by ICP in 93% of 27 samples. Isotope ratios of lead in meat matched the ratios of bullets, and differed from background lead in bone. We fed fragment-containing venison to four pigs to test bioavailability; four controls received venison without fragments from the same deer. Mean blood lead concentrations in pigs peaked at 2.29 microg/dL (maximum 3.8 microg/dL 2 days following ingestion of fragment-containing venison, significantly higher than the 0.63 microg/dL averaged by controls. We conclude that people risk exposure to bioavailable lead from bullet fragments when they eat venison from deer killed with standard lead-based rifle bullets and processed under normal procedures. At risk in the U.S. are some ten million hunters, their families, and low

  7. Antimony sinks in the weathering crust of bullets from Swiss shooting ranges

    International Nuclear Information System (INIS)

    Ackermann, Sonia; Giere, Reto; Newville, Matthew; Majzlan, Juraj

    2009-01-01

    Shooting ranges represent sites heavily polluted by Pb, Sb, Cu, Ni, and Zn, which are released during the weathering of bullets. The pristine bullets are made of a Pb-Sb core, Fe mantle, and minor amounts of Cu, Ni, and Zn in an interlayer between the core and mantle. At two selected sampling sites (Losone and Lucerne, both in Switzerland), corroding bullets were collected to determine the sinks of Sb within the weathering crust of the bullets. Bulk Sb concentrations in the crust were found to be as high as 1.3 wt.%. The oxalate-extractable fraction of Fe showed that the amorphous Fe oxides (e.g., ferrihydrite) prevail over goethite and lepidocrocite, which were identified by bulk X-ray diffraction experiments. Crystalline Pb phases are litharge (only found by X-ray diffraction) and cerussite, which result from weathering of the Pb core. No distinct Sb minerals were identified by X-ray diffraction. Investigations with electron microprobe (EMP) showed that Sb is mostly accumulated in those regions in the weathering crust where there is also a high concentration of Fe. In the weathering crust from Losone, such Fe-rich regions with Sb are represented by material that cements or rims silicate mineral grains. The cement was identified as lepidocrocite by micro-Raman analysis. At Lucerne, Sb is found in Fe-oxide aggregates, in sawdust particles where it may be bound to organic matter, or in aggregates enriched in Pb and depleted in Fe. Bulk EXAFS experiments suggested that the Fe oxides are the most important sink for Sb. Our modelling of Sb next-nearest neighbours suggests two types of inner-sphere complexes on the surfaces of Fe oxides. These are edge- and corner-sharing adsorption complexes. Hence, the predominant sink of Sb in the weathering crust of the bullets at the selected shooting ranges is Fe oxides, amorphous or crystalline

  8. Hydrodynamics of back spatter by blunt bullet gunshot with a link to bloodstain pattern analysis

    Science.gov (United States)

    Comiskey, P. M.; Yarin, A. L.; Attinger, D.

    2017-07-01

    A theoretical model describing the blood spatter pattern resulting from a blunt bullet gunshot is proposed. The predictions are compared to experimental data acquired in the present work. This hydrodynamic problem belongs to the class of the impact hydrodynamics with the pressure impulse generating the blood flow. At the free surface, the latter is directed outwards and accelerated toward the surrounding air. As a result, the Rayleigh-Taylor instability of the flow of blood occurs, which is responsible for the formation of blood drops of different sizes and initial velocities. Thus, the initial diameter, velocity, and acceleration of the atomized blood drops can be determined. Then, the equations of motion are solved, describing drop trajectories in air accounting for gravity, and air drag. Also considered are the drop-drop interactions through air, which diminish air drag on the subsequent drops. Accordingly, deposition of two-phase (blood-drop and air) jets on a vertical cardstock sheet located between the shooter and the target (and perforated by the bullet) is predicted and compared with experimental data. The experimental data were acquired with a porous polyurethane foam sheet target impregnated with swine blood, and the blood drops were collected on a vertical cardstock sheet which was perforated by the blunt bullet. The highly porous target possesses a low hydraulic resistance and therefore resembles a pool of blood shot by a blunt bullet normally to its free surface. The back spatter pattern was predicted numerically and compared to the experimental data for the number of drops, their area, the total stain area, and the final impact angle as functions of radial location from the bullet hole in the cardstock sheet (the collection screen). Comparisons of the predicted results with the experimental data revealed satisfactory agreement. The predictions also allow one to find the impact Weber number on the collection screen, which is necessary to predict stain

  9. A Molecular-line Study of the Interstellar Bullet Engine IRAS05506+2414

    Science.gov (United States)

    Sahai, Raghvendra; Lee, Chin-Fei; Sánchez Contreras, Carmen; Patel, Nimesh; Morris, Mark R.; Claussen, Mark

    2017-12-01

    We present interferometric and single-dish molecular line observations of the interstellar bullet-outflow source IRAS 05506+2414, whose wide-angle bullet spray is similar to the Orion BN/KL explosive outflow and likely arises from an entirely different mechanism than the classical accretion-disk-driven bipolar flows in young stellar objects. The bullet-outflow source is associated with a large pseudo-disk and three molecular outflows—a high-velocity outflow (HVO), a medium-velocity outflow (MVO), and a slow, extended outflow (SEO). The size (mass) of the pseudo-disk is 10,350 au × 6400 au (0.64-0.17 M ⊙) from a model-fit assuming infall and rotation, we derive a central stellar mass of 8-19 M ⊙. The HVO (MVO) has an angular size ˜5180 (˜3330) au and a projected outflow velocity of ˜140 km s-1 (˜30 km s-1). The SEO size (outflow speed) is ˜0.9 pc (˜6 km s-1). The HVO’s axis is aligned with (orthogonal to) that of the SEO (pseudo-disk). The velocity structure of the MVO is unresolved. The scalar momenta in the HVO and SEO are very similar, suggesting that the SEO has resulted from the HVO interacting with ambient-cloud material. The bullet spray shares a common axis with the pseudo-disk and has an age comparable to that of MVO (few hundred years), suggesting that these three structures are intimately linked. We discuss several models for the outflows in IRAS 05506+2414 (including dynamical decay of a stellar cluster, chance encounter of a runaway star with a dense cloud, and close passage of two protostars), and conclude that second-epoch imaging to derive proper motions of the bullets and nearby stars can help to discriminate between them.

  10. Stabilizing lead bullets in shooting range soil by phosphate-based surface coating

    Directory of Open Access Journals (Sweden)

    Bin Hua

    2016-08-01

    Full Text Available Soil lead (Pb is well known as a threat to human health and ecosystem. Although relatively insoluble, lead bullets in shooting range soil can be readily released into soluble forms through natural weathering processes and thus pose significant human and environmental risks. In this study, laboratory experiments were conducted to investigate if the Pb bullets in shooting range soil can be stabilized through surface coating of phosphate-based materials. Results indicated that FePO4 or AlPO4 coatings, insoluble metal phosphates, have been successfully formed on the surface of the Pb bullets. The EPA Toxicity Characteristic Leaching Procedure (TCLP test showed that FePO4 or AlPO4 surface coating would effectively reduce the Pb solubility or leachability of the bullets. The surface coating under pH of <5.5 for 7 days could achieve 92–100% reduction, with 85–98% by FePO4 coating and 77–98% by AlPO4 coating as compared with the non-coating. Leachable Pb concentration in the contaminated shooting range soil was reduced by 85–98% or 77–98% as a result of the FePO4 or AlPO4 solution treatment. This study demonstrated that the FePO4 or AlPO4–based surface coating on lead bullets can effectively inhibit the Pb weathering and significantly reduce the Pb release from soil through in situ chemical stabilization, which could be potentially applicable as a cost-effective and environmental-sound technology for the remediation of Pb-contaminated shooting range soil.

  11. Long Wavelength Electromagnetic Light Bullets Generated by a 10.6 micron CO2 Ultrashort Pulsed Source

    Science.gov (United States)

    2016-11-29

    AFRL-AFOSR-VA-TR-2016-0365 Long Wavelength Electromagnetic Light Bullets Generated by a 10.6 micron CO2 Ultrashort Pulsed Source Jerome Moloney...SUBTITLE "Long Wavelength Electromagnetic Light Bullets Generated by a 10.6 micron CO2 Ultrashort Pulsed Source 5a. CONTRACT NUMBER FA9550-15-1-0272 5b...Wavelength Electromagnetic Light Bullets Generated by a 10 µm CO2 Ultrashort Pulsed Source Grant/Contract Number AFOSR assigned control number. It must

  12. Classifying Classifications

    DEFF Research Database (Denmark)

    Debus, Michael S.

    2017-01-01

    This paper critically analyzes seventeen game classifications. The classifications were chosen on the basis of diversity, ranging from pre-digital classification (e.g. Murray 1952), over game studies classifications (e.g. Elverdam & Aarseth 2007) to classifications of drinking games (e.g. LaBrie et...... al. 2013). The analysis aims at three goals: The classifications’ internal consistency, the abstraction of classification criteria and the identification of differences in classification across fields and/or time. Especially the abstraction of classification criteria can be used in future endeavors...... into the topic of game classifications....

  13. Damage to apparel layers and underlying tissue due to hand-gun bullets.

    Science.gov (United States)

    Carr, Debra; Kieser, Jules; Mabbott, Alexander; Mott, Charlotte; Champion, Stephen; Girvan, Elizabeth

    2014-01-01

    Ballistic damage to the clothing of victims of gunshot wounds to the chest can provide useful forensic evidence. Anyone shot in the torso will usually be wearing clothing which will be damaged by the penetrating impact event and can reportedly be the source of some of the debris in the wound. Minimal research has previously been reported regarding the effect of bullets on apparel fabrics and underlying tissue. This paper examines the effect of ammunition (9 mm full metal jacket [FMJ] DM11 A1B2, 8.0 g; and soft point flat nose Remington R357M3, 10.2 g) on clothing layers that cover the torso (T-shirt, T-shirt plus hoodie, T-shirt plus denim jacket) and underlying structures represented by porcine thoracic wall (skin, underlying tissue, ribs). Impacts were recorded using a Phantom V12 high speed camera. Ejected bone debris was collected before wound tracts were dissected and measured; any debris found was recovered for further analysis. Size and mass of bony debris was recorded; fibre debris recovered from the wound and impact damage to fabrics were imaged using scanning electron microscopy (SEM). Remington R357M3 ammunition was characteristically associated with stellate fabric damage; individual fibres were less likely to show mushrooming. In contrast, 9 mm FMJ ammunition resulted in punch-out damage to fabric layers, with mushrooming of individual fibres being more common. Entry wound sizes were similar for both types of ammunition and smaller than the diameter of the bullet that caused them. In this work, the Remington R357M3 ammunition resulted in larger exit wounds due to the bullet construction which mushroomed. That fabric coverings did not affect the amount of bony debris produced is interesting, particularly given there was some evidence that apparel layers affected the size of the wound. Recent work has suggested that denim (representative of jeans) can exacerbate wounding caused by high-velocity bullet impacts to the thigh when the bullet does not

  14. A Fortunate Story of an Unusual AK-47 Bullet Trajectory: Always Keep a Smartphone in Your Pocket.

    Science.gov (United States)

    Thabouillot, Oscar; Perrier, Pierre; Roche, Nicolas-Charles; Agard, David; Barbier, Olivier; Martin, Guillaume; Viant, Eric; Leclere, Jean-Baptiste

    2016-06-01

    This is a report of a fortunate story of an unusual AK-47 bullet trajectory which took place during the Paris (France) attack of November 13th, 2015. A young man, trying to protect his girlfriend, interfered between her and a shooter. He had been wounded in the posterior compartment of the thigh. The bullet penetrated him and, instead of exiting, rebound against his Smartphone, which was in the front pocket of his pants. Thanks to that, the missile bullet did not injure his girlfriend but ended its trajectory in the fat tissue of his thigh. Thabouillot O , Perrier P , Roche NC , Agard D , Barbier O , Martin G , Viant E , Leclere JB . A fortunate story of an unusual AK-47 bullet trajectory: always keep a Smartphone in your pocket. Prehosp Disaster Med, 2016;31(3):343-345.

  15. Biological and Health Effects of Electromagnetic (Nonionizing) Radiation. LC Science Tracer Bullet.

    Science.gov (United States)

    Halasz, Hisako, Comp.

    The environment we live in today is filled with human-created electromagnetic fields generated by a variety of sources, including radio and television transmitters, power lines, and visual display terminals. (In addition, there exists a natural background of electromagnetic fields.) The term "electromagnetic pollution" is often used to…

  16. Atmospheric-pressure plasma jets: Effect of gas flow, active species, and snake-like bullet propagation

    Energy Technology Data Exchange (ETDEWEB)

    Wu, S.; Wang, Z.; Huang, Q.; Tan, X.; Lu, X. [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074 (China); Ostrikov, K. [CSIRO Materials Science and Engineering, PO Box 218, Lindfield NSW 2070 (Australia); School of Physics, University of Sydney, Sydney NSW 2006 (Australia); State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074 (China)

    2013-02-15

    Cold atmospheric-pressure plasma jets have recently attracted enormous interest owing to numerous applications in plasma biology, health care, medicine, and nanotechnology. A dedicated study of the interaction between the upstream and downstream plasma plumes revealed that the active species (electrons, ions, excited OH, metastable Ar, and nitrogen-related species) generated by the upstream plasma plume enhance the propagation of the downstream plasma plume. At gas flows exceeding 2 l/min, the downstream plasma plume is longer than the upstream plasma plume. Detailed plasma diagnostics and discharge species analysis suggest that this effect is due to the electrons and ions that are generated by the upstream plasma and flow into the downstream plume. This in turn leads to the relatively higher electron density in the downstream plasma. Moreover, high-speed photography reveals a highly unusual behavior of the plasma bullets, which propagate in snake-like motions, very differently from the previous reports. This behavior is related to the hydrodynamic instability of the gas flow, which results in non-uniform distributions of long-lifetime active species in the discharge tube and of surface charges on the inner surface of the tube.

  17. Automatic identification of bullet signatures based on consecutive matching striae (CMS) criteria.

    Science.gov (United States)

    Chu, Wei; Thompson, Robert M; Song, John; Vorburger, Theodore V

    2013-09-10

    The consecutive matching striae (CMS) numeric criteria for firearm and toolmark identifications have been widely accepted by forensic examiners, although there have been questions concerning its observer subjectivity and limited statistical support. In this paper, based on signal processing and extraction, a model for the automatic and objective counting of CMS is proposed. The position and shape information of the striae on the bullet land is represented by a feature profile, which is used for determining the CMS number automatically. Rapid counting of CMS number provides a basis for ballistics correlations with large databases and further statistical and probability analysis. Experimental results in this report using bullets fired from ten consecutively manufactured barrels support this developed model. Published by Elsevier Ireland Ltd.

  18. USING THE BULLET CLUSTER AS A GRAVITATIONAL TELESCOPE TO STUDY z ∼> 7 LYMAN BREAK GALAXIES

    International Nuclear Information System (INIS)

    Hall, Nicholas; Bradač, Maruša; Gonzalez, Anthony H.; Treu, Tommaso; Clowe, Douglas; Jones, Christine; Stiavelli, Massimo; Zaritsky, Dennis; Cuby, Jean-Gabriel; Clément, Benjamin

    2012-01-01

    We use imaging obtained with the Hubble Space Telescope Wide Field Camera 3 to search for z 850 dropouts at z ∼ 7 and J 110 dropouts at z ∼ 9 lensed by the Bullet Cluster. In total we find 10 z 850 dropouts in our 8.27 arcmin 2 field. Using magnification maps from a combined weak- and strong-lensing mass reconstruction of the Bullet Cluster and correcting for estimated completeness levels, we calculate the surface density and luminosity function of our z 850 dropouts as a function of intrinsic (accounting for magnification) magnitude. We find results consistent with published blank field surveys, despite using much shallower data, and demonstrate the effectiveness of cluster surveys in the search for z ∼ 7 galaxies.

  19. Distributed radar network for real-time tracking of bullet trajectory

    Science.gov (United States)

    Zhang, Yimin; Li, Xin; Jin, Yuanwei; Amin, Moeness G.; Eydgahi, Ali

    2009-05-01

    Gunshot detection, sniper localization, and bullet trajectory prediction are of significant importance in military and homeland security applications. While the majority of existing work is based on acoustic and electro-optical sensors, this paper develops a framework of networked radar systems that uses distributed radar sensor networks to achieve the aforementioned objectives. The use of radio frequency radar systems allows the achievement of subtime- of-flight tracking response, enabling to response before the bullet reaches its target and, as such, effectively leading to the reduction of injuries and casualties in military and homeland security operations. The focus of this paper is to examine the MIMO radar concept with concurrent transmission of low-correlation waveforms from multiple radar sets to ensure wide surveillance coverage and maintain a high waveform repetition frequency for long coherent time interval required to achieve return signal concentration.

  20. [Bullet and shrapnel injuries in the face and neck regions. Current aspects of wound ballistics].

    Science.gov (United States)

    Hauer, T; Huschitt, N; Kulla, M; Kneubuehl, B; Willy, C

    2011-08-01

    A basic understanding of the ballistic behaviour of projectiles or fragments after entering the human body is essential for the head and neck surgeon in the military environment in order to anticipate the diagnostic and therapeutic consequences of this type of injury. Although a large number of factors influence the missile in flight and after penetration of the body, the most important factor is the amount of energy transmitted to the tissue. Long guns (rifles or shotguns) have a much higher muzzle energy compared to handguns, explaining why the remote effects beyond the bullet track play a major role. While most full metal jacket bullets release their energy after 12-20 cm (depending on the calibre), soft point bullets release their energy immediately after entry into the human body. This results in a major difference in extremity wounds, but not so much in injuries with long bullet paths (e.g. diagonal shots). Shrapnel wounds are usually produced with similarly high kinetic energy to those caused by hand- and long guns. However, fragments tend to dissipate the entire amount of energy within the body, which increases the degree of tissue disruption. Of all relevant injuries in the head and neck region, soft tissue injuries make up the largest proportion (60%), while injuries to the face are seen three times more often than injuries to the neck. Concomitant intracranial or spinal injury is seen in 30% of cases. Due to high levels of wound contamination, the infection rate is approximately 15%, often associated with a complicated and/or multiresistant spectrum of germs.

  1. Adaptive Generation and Diagnostics of Linear Few-Cycle Light Bullets

    Directory of Open Access Journals (Sweden)

    Martin Bock

    2013-02-01

    Full Text Available Recently we introduced the class of highly localized wavepackets (HLWs as a generalization of optical Bessel-like needle beams. Here we report on the progress in this field. In contrast to pulsed Bessel beams and Airy beams, ultrashort-pulsed HLWs propagate with high stability in both spatial and temporal domain, are nearly paraxial (supercollimated, have fringe-less spatial profiles and thus represent the best possible approximation to linear “light bullets”. Like Bessel beams and Airy beams, HLWs show self-reconstructing behavior. Adaptive HLWs can be shaped by ultraflat three-dimensional phase profiles (generalized axicons which are programmed via calibrated grayscale maps of liquid-crystal-on-silicon spatial light modulators (LCoS-SLMs. Light bullets of even higher complexity can either be freely formed from quasi-continuous phase maps or discretely composed from addressable arrays of identical nondiffracting beams. The characterization of few-cycle light bullets requires spatially resolved measuring techniques. In our experiments, wavefront, pulse and phase were detected with a Shack-Hartmann wavefront sensor, 2D-autocorrelation and spectral phase interferometry for direct electric-field reconstruction (SPIDER. The combination of the unique propagation properties of light bullets with the flexibility of adaptive optics opens new prospects for applications of structured light like optical tweezers, microscopy, data transfer and storage, laser fusion, plasmon control or nonlinear spectroscopy.

  2. Simulating direct shear tests with the Bullet physics library: A validation study.

    Science.gov (United States)

    Izadi, Ehsan; Bezuijen, Adam

    2018-01-01

    This study focuses on the possible uses of physics engines, and more specifically the Bullet physics library, to simulate granular systems. Physics engines are employed extensively in the video gaming, animation and movie industries to create physically plausible scenes. They are designed to deliver a fast, stable, and optimal simulation of certain systems such as rigid bodies, soft bodies and fluids. This study focuses exclusively on simulating granular media in the context of rigid body dynamics with the Bullet physics library. The first step was to validate the results of the simulations of direct shear testing on uniform-sized metal beads on the basis of laboratory experiments. The difference in the average angle of mobilized frictions was found to be only 1.0°. In addition, a very close match was found between dilatancy in the laboratory samples and in the simulations. A comprehensive study was then conducted to determine the failure and post-failure mechanism. We conclude with the presentation of a simulation of a direct shear test on real soil which demonstrated that Bullet has all the capabilities needed to be used as software for simulating granular systems.

  3. Measurement of bullet impact conditions using automated in-flight photography system

    Directory of Open Access Journals (Sweden)

    Ryan Decker

    2017-08-01

    Full Text Available Knowledge of impact conditions is critical to evaluating the terminal impact performance of a projectile. For a small caliber bullet, in-flight velocity has been precisely measured for decades using detection screens, but accurately quantifying the orientation of the bullet on a target has been more challenging. This report introduces the Automated Small-Arms Photogrammetry (ASAP analysis method used to measure, model, and predict the orientation of a small caliber bullet before reaching an impact surface. ASAP uses advanced hardware developed by Sydor Technologies to record a series of infrared digital photographs. Individual images (four orthogonal pairs are processed using computer vision algorithms to quantify the orientation of the projectile and re-project its precise position and orientation into a three-dimensional muzzle-fixed coordinate system. An epicyclic motion model is fit to the measured data, and the epicyclic motion is extrapolated to the target location. Analysis results are fairly immediate and may be reviewed during testing. Prove-out demonstrations have shown that the impact-angle prediction capability is less than six hundredths of a degree for the 5.56 mm ball round tested. Keywords: Yaw, Terminal ballistics, Exterior ballistics, Test & evaluation, Computer vision, Image processing, Angle of attack

  4. Experimentally Studied Influence of the Bullet Head Shape on Dispersion Characteristics at Subsonic Airspeeds

    Directory of Open Access Journals (Sweden)

    S. N. Ilukhin

    2015-01-01

    Full Text Available The article presents description and results of experiments on a ballistic track and subsonic wind tunnel. The subject of study is important an issue such as the assessment of the influence of the bullet head shape on the accuracy of shooting parameters at subsonic muzzle velocity. The article points to the features of examined precision of guided and unguided aircraft, refers to the main disturbing factors. In addition, it outlines the most well known ways to improve the flight precision of unguided munitions. The article presents the geometric parameters of bullets and their scale models used in the experiments. It describes the experimental facilities and the studies themselves. Particular attention is paid to the analysis of experimental air-gun firings. Results for different muzzle velocities of flight are compared. The paper notes an ambiguity in comparison of accuracy and head drag coefficient. The results are clearly aligned with the data purging in the little turbulent subsonic wind tunnel. The article describes in detail the use of the method for visualizing a structure of the flow for the delimitation of attached flow and estimation of stagnation zone. A revealed physical picture has comprehensive theoretical underpinning. The conclusions of the work also give a advices on selecting a bullet to have the best dispersion parameters.

  5. Confluence or independence of microwave plasma bullets in atmospheric argon plasma jet plumes

    Science.gov (United States)

    Li, Ping; Chen, Zhaoquan; Mu, Haibao; Xu, Guimin; Yao, Congwei; Sun, Anbang; Zhou, Yuming; Zhang, Guanjun

    2018-03-01

    Plasma bullet is the formation and propagation of a guided ionization wave (streamer), normally generated in atmospheric pressure plasma jet (APPJ). In most cases, only an ionization front produces in a dielectric tube. The present study shows that two or three ionization fronts can be generated in a single quartz tube by using a microwave coaxial resonator. The argon APPJ plumes with a maximum length of 170 mm can be driven by continuous microwaves or microwave pulses. When the input power is higher than 90 W, two or three ionization fronts propagate independently at first; thereafter, they confluence to form a central plasma jet plume. On the other hand, the plasma bullets move independently as the lower input power is applied. For pulsed microwave discharges, the discharge images captured by a fast camera show the ionization process in detail. Another interesting finding is that the strongest lightening plasma jet plumes always appear at the shrinking phase. Both the discharge images and electromagnetic simulations suggest that the confluence or independent propagation of plasma bullets is resonantly excited by the local enhanced electric fields, in terms of wave modes of traveling surface plasmon polaritons.

  6. Failure mechanism of resistance-spot-welded specimens impacted on base material by bullets

    Directory of Open Access Journals (Sweden)

    Chunlei Fan

    2018-01-01

    Full Text Available The tests of bullet impact on the base material (BM of a simple specimen with a single resistance-spot-welded (RSW nugget of TRIP800 steel are performed to investigate the response of the RSW specimen to the ballistic debris impact on the RSW specimen. A one-stage gas gun is used to fire the bullets while a laser velocity interferometer system for any reflector (VISAR is used to measure the velocity histories of the free surfaces of the RSW specimen. The recovered RSW specimens are examined with the three-dimensional super depth digital microscope (SDDM and the scanning electro microscope (SEM. For the tests of small multiple-bullet impact, it is revealed that the wave train of the VISAR measured results and the detachment of the base material interfaces in the recovered RSW specimens are directly related to the reflection and refraction of the curved stress waves incoming to the interfaces and the free surfaces in the RSW specimens. The detachment of BM interfaces can lead to the impact failure of the RSW joints for the larger multiple-bullet impact at higher velocity, the mechanism of which is different from the case for normal incidence (spalling. For the tests of single large bullet impact, it is brought to light experimentally that the plastic strain concentration at the “notch tip” spurs either the crack near the RSW joint or the split of the nugget. The numerical simulation shows up the process of splitting the nugget: a crack initiates at the “notch tip”, propagates across the nugget interface and splits the nugget into two parts. It is indicated that the interaction between the stress waves and many interfaces/free surfaces in the RSW specimen under ballistic impact causes variable local stress triaxialities and stress Lode angles, which affects the deformation and fracture mechanism of the RSW specimen including stretching and shearing failure. It is shown that the impact failure of the RSW joints is a mixture of brittle

  7. Failure mechanism of resistance-spot-welded specimens impacted on base material by bullets

    Science.gov (United States)

    Fan, Chunlei; Ma, Bohan; Chen, Danian; Wang, Huanran; Ma, Dongfang

    2018-01-01

    The tests of bullet impact on the base material (BM) of a simple specimen with a single resistance-spot-welded (RSW) nugget of TRIP800 steel are performed to investigate the response of the RSW specimen to the ballistic debris impact on the RSW specimen. A one-stage gas gun is used to fire the bullets while a laser velocity interferometer system for any reflector (VISAR) is used to measure the velocity histories of the free surfaces of the RSW specimen. The recovered RSW specimens are examined with the three-dimensional super depth digital microscope (SDDM) and the scanning electro microscope (SEM). For the tests of small multiple-bullet impact, it is revealed that the wave train of the VISAR measured results and the detachment of the base material interfaces in the recovered RSW specimens are directly related to the reflection and refraction of the curved stress waves incoming to the interfaces and the free surfaces in the RSW specimens. The detachment of BM interfaces can lead to the impact failure of the RSW joints for the larger multiple-bullet impact at higher velocity, the mechanism of which is different from the case for normal incidence (spalling). For the tests of single large bullet impact, it is brought to light experimentally that the plastic strain concentration at the "notch tip" spurs either the crack near the RSW joint or the split of the nugget. The numerical simulation shows up the process of splitting the nugget: a crack initiates at the "notch tip", propagates across the nugget interface and splits the nugget into two parts. It is indicated that the interaction between the stress waves and many interfaces/free surfaces in the RSW specimen under ballistic impact causes variable local stress triaxialities and stress Lode angles, which affects the deformation and fracture mechanism of the RSW specimen including stretching and shearing failure. It is shown that the impact failure of the RSW joints is a mixture of brittle fracture and ductile

  8. Investigation of effective forensic cleaning methods for bullet and cartridge case samples

    Science.gov (United States)

    Shuherk, Cassie Marie

    Bullet and cartridge case evidence may potentially link weapons and crimes through the comparison of toolmark patterns. This analysis relies on the clarity of the toolmarks and the ability of the examiner to identify patterns on the evidence. These patterns may be distorted by debris such as soil, blood, cyanoacrylate, and construction materials. Despite the potential importance of bullet and cartridge case evidence, few investigations of proper cleaning methods have been conducted. The present study was designed to examine the effects of various cleaning solutions and application methods on copper and brass bullets and cartridge cases. Additionally, this research investigated the efficacy of these cleaning protocols on the common evidence contaminants blood and cyanoacrylate. No cleaning method was found to be universally effective on both contaminant types and nondestructive to the metal surface. Ultrasonication was the most efficient application method employed when used in conjunction with an appropriate cleaning solution. Acetone proved to be safe and successful at removing heavy cyanoacrylate deposits from brass cartridge cases without damaging the metal. Although sulfuric acid removed most of the cyanoacrylate from the brass cartridge case, ultrasonication of the fumed cartridge cases in sulfuric acid caused the nickel-plated primer caps to turn black. Additionally, etching occurred when sulfuric acid was allowed to dry on the cartridge case surface. Citric acid, salt-flour-vinegar paste, TergazymeRTM, and water did not effectively remove the cyanoacrylate from the cartridge cases, but the solutions were safe to use on the brass and sometimes resulted in a shinier surface. Regardless of the cleaning method employed, the bloodstained bullets retained most or all of the underlying brown tarnish. Ultrasonication with sulfuric acid was successful at removing some blood-initiated tarnishing; however, the removal of residues was not complete, making it difficult

  9. Biological effects of radiation

    International Nuclear Information System (INIS)

    2013-01-01

    This fourth chapter presents: cell structure and metabolism; radiation interaction with biological tissues; steps of the production of biological effect of radiation; radiosensitivity of tissues; classification of biological effects; reversibility, transmissivity and influence factors; pre-natal biological effects; biological effects in therapy and syndrome of acute irradiation

  10. The benefit of a tough skin: bullet holes, weathering and the preservation of heritage

    Science.gov (United States)

    Mol, Lisa; Gomez-Heras, M.; Brassey, C.; Green, O.; Blenkinsop, T.

    2017-02-01

    Projectile damage to building stone is a widespread phenomenon. Sites damaged 100 years ago during the First World War still see daily use, while in a more contemporary setting numerous reports show the damage to buildings in Babylon, Mosul and Palmyra. While research has been carried out on the long-term effects of conflict such as fire damage, little is known about the protracted damage sustained through the impact of bullets, shrapnel and other metal projectiles outside of the field of engineering focused on ceramics and metals. To investigate alterations to mineral structure caused by projectile damage, impacts were created in medium-grained, well-compacted, mesoporous sandstone samples using 0.22 calibre lead bullets shot at a distance of 20 m. Half these samples were treated with a surface consolidant (Wacker OH 100), to mimic natural cementation of the rock surface. These samples were then tested for changes to surface hardness and moisture movement during temperature cycles of 15-65°C. Petrographic thin section analysis was carried out to investigate the micro-scale deformation associated with high-speed impact. The results surprisingly show that stress build-up behind pre-existing cementation of the surface, as found in heritage sites that have been exposed to moisture and temperature fluctuations for longer periods of time, can be alleviated with a bullet impact. However, fracture networks and alteration of the mineral matrices still form a weak point within the structure, even at a relatively low impact calibre. This initial study illustrates the need for geomorphologists, geologists, engineers and heritage specialists to work collectively to gain further insights into the long-term impact of higher calibre armed warfare on heritage deterioration.

  11. A Bullet Entered through the Open Mouth and Ended Up in the Parapharyngeal Space and Skull Base

    Directory of Open Access Journals (Sweden)

    Saileswar Goswami

    2015-01-01

    Full Text Available Shot from a revolver from a close range, a bullet pierced the chest of a policeman and entered through the open mouth of a young male person standing behind. The entry wound was found in the cheek mucosa adjacent to the left lower third molar. After hitting and fracturing the body and the ramus of the mandible, the bullet was deflected and was finally lodged in the parapharyngeal space and skull base, anterolateral to the transverse process of the atlas. The great vessels of the neck were not injured. The patient’s condition was very critical but his life could be saved. The bullet was approached through a modified Blair’s incision and was found to be lying over the carotid sheath. It was removed safely and the patient recovered completely.

  12. Three-dimensional Bessel light bullets in self-focusing Kerr media

    International Nuclear Information System (INIS)

    Zhong Weiping; Belic, Milivoj; Huang Tingwen

    2010-01-01

    We study three-dimensional (3D) Bessel light-bullet solutions of the nonlinear Schroedinger equation with a photonic lattice potential in the form of squared Bessel functions in polar coordinates, both analytically and numerically. Analytical solutions are obtained by the Hartree approximation, and numerical simulations are performed, to compare with the analytical solutions and to confirm the stability of localized solutions. The 3D spatial wave packets are built by the products of hyperbolic secant and Bessel functions. These solitons appear in different forms, such as 3D vortex solitons and multipole solitons.

  13. Dark matter line emission constraints from NuSTAR observations of the Bullet Cluster

    DEFF Research Database (Denmark)

    Riemer-Sørensen, S.; Wik, D.; Madejski, G.

    2015-01-01

    Some dark matter candidates, e.g., sterile neutrinos, provide observable signatures in the form of mono-energetic line emission. We present the first search for dark matter line emission in the range in a pointed observation of the Bullet Cluster with NuSTAR. We do not detect any significant line...... emission and instead we derive upper limits (95% CL) on the flux, and interpret these constraints in the context of sterile neutrinos and more generic dark matter candidates. NuSTAR does not have the sensitivity to constrain the recently claimed line detection at , but improves on the constraints...... for energies of 10–25 keV....

  14. Lipossomas: a bala mágica acertou? Liposomes: has the magic bullet hit the target?

    Directory of Open Access Journals (Sweden)

    Nuno C. Santos

    2002-12-01

    Full Text Available Efficient drug delivery systems are as important as drug themselves. A powerful drug unable to reach the target cell is useless in practice. Ehrlich's Magic Bullet was the first carrier system to be proposed. The evolution in this domain has been quite slow as the natural mechanisms of mammals against foreign products are hard to overcome. However, lipid-based systems (liposomes and related vesicles have attained reasonable success. The basic preparations and structural features of liposomes and related vesicles as well as their applications are addressed from the chemist's and biochemist's point of view.

  15. Investigating the use of support vector machine classification on structural brain images of preterm-born teenagers as a biological marker.

    Directory of Open Access Journals (Sweden)

    Carlton Chu

    Full Text Available Preterm birth has been shown to induce an altered developmental trajectory of brain structure and function. With the aid support vector machine (SVM classification methods we aimed to investigate whether MRI data, collected in adolescence, could be used to predict whether an individual had been born preterm or at term. To this end we collected T1-weighted anatomical MRI data from 143 individuals (69 controls, mean age 14.6y. The inclusion criteria for those born preterm were birth weight ≤ 1500g and gestational age < 37w. A linear SVM was trained on the grey matter segment of MR images in two different ways. First, all the individuals were used for training and classification was performed by the leave-one-out method, yielding 93% correct classification (sensitivity = 0.905, specificity = 0.942. Separately, a random half of the available data were used for training twice and each time the other, unseen, half of the data was classified, resulting 86% and 91% accurate classifications. Both gestational age (R = -0.24, p<0.04 and birth weight (R = -0.51, p < 0.001 correlated with the distance to decision boundary within the group of individuals born preterm. Statistically significant correlations were also found between IQ (R = -0.30, p < 0.001 and the distance to decision boundary. Those born small for gestational age did not form a separate subgroup in these analyses. The high rate of correct classification by the SVM motivates further investigation. The long-term goal is to automatically and non-invasively predict the outcome of preterm-born individuals on an individual basis using as early a scan as possible.

  16. General-Purpose Heat Source development: Safety Verification Test Program. Bullet/fragment test series

    Energy Technology Data Exchange (ETDEWEB)

    George, T.G.; Tate, R.E.; Axler, K.M.

    1985-05-01

    The radioisotope thermoelectric generator (RTG) that will provide power for space missions contains 18 General-Purpose Heat Source (GPHS) modules. Each module contains four /sup 238/PuO/sub 2/-fueled clads and generates 250 W/sub (t)/. Because a launch-pad or post-launch explosion is always possible, we need to determine the ability of GPHS fueled clads within a module to survive fragment impact. The bullet/fragment test series, part of the Safety Verification Test Plan, was designed to provide information on clad response to impact by a compact, high-energy, aluminum-alloy fragment and to establish a threshold value of fragment energy required to breach the iridium cladding. Test results show that a velocity of 555 m/s (1820 ft/s) with an 18-g bullet is at or near the threshold value of fragment velocity that will cause a clad breach. Results also show that an exothermic Ir/Al reaction occurs if aluminum and hot iridium are in contact, a contact that is possible and most damaging to the clad within a narrow velocity range. The observed reactions between the iridium and the aluminum were studied in the laboratory and are reported in the Appendix.

  17. Generation and control of sound bullets with a nonlinear acoustic lens.

    Science.gov (United States)

    Spadoni, Alessandro; Daraio, Chiara

    2010-04-20

    Acoustic lenses are employed in a variety of applications, from biomedical imaging and surgery to defense systems and damage detection in materials. Focused acoustic signals, for example, enable ultrasonic transducers to image the interior of the human body. Currently however the performance of acoustic devices is limited by their linear operational envelope, which implies relatively inaccurate focusing and low focal power. Here we show a dramatic focusing effect and the generation of compact acoustic pulses (sound bullets) in solid and fluid media, with energies orders of magnitude greater than previously achievable. This focusing is made possible by a tunable, nonlinear acoustic lens, which consists of ordered arrays of granular chains. The amplitude, size, and location of the sound bullets can be controlled by varying the static precompression of the chains. Theory and numerical simulations demonstrate the focusing effect, and photoelasticity experiments corroborate it. Our nonlinear lens permits a qualitatively new way of generating high-energy acoustic pulses, which may improve imaging capabilities through increased accuracy and signal-to-noise ratios and may lead to more effective nonintrusive scalpels, for example, for cancer treatment.

  18. To drink or grasp? How bullet ants ( Paraponera clavata) differentiate between sugars and proteins in liquids

    Science.gov (United States)

    Jandt, Jennifer; Larson, Hannah K.; Tellez, Peter; McGlynn, Terrence P.

    2013-12-01

    Flexibility in behavior can increase the likelihood that a forager may respond optimally in a fluctuating environment. Nevertheless, physiological or neuronal constraints may result in suboptimal responses to stimuli. We observed foraging workers of the giant tropical ant (also referred to as the "bullet ant"), Paraponera clavata, as they reacted to liquid solutions with varying concentrations of sugar and protein. We show that when protein/sucrose concentration is high, many bullet ants will often try to grasp at the droplet, rather than gather it by drinking. Because P. clavata actively hunt for prey, fixed action patterns and rapid responses to protein may be adaptively important, regardless of the medium in which it is presented. We conclude that, in P. clavata, food-handling decisions are made in response to the nutrient content of the food rather than the texture of the food. Further, we suggest that colonies that maintain a mixture of individuals with consistent fixed or flexible behavioral responses to food-handling decisions may be better adapted to fluctuating environmental conditions, and we propose future studies that could address this.

  19. Atmospheric pressure plasma jets : properties of plasma bullets and the dynamics of the interaction with dielectric surfaces

    NARCIS (Netherlands)

    Sobota, A.; Slikboer, E.; Guaitella, O.Y.N.

    2015-01-01

    Cold atmospheric pressure plasma jets, although mostly researched for applications in surface treatment, are rarely investigated in the presence of a surface. This paper presents the properties of plasma bullets formed in the capillary as well as the dynamics of the propagation of the plasma on

  20. The Dream About the Magic Silver Bullet – the Complexity of Designing for Tablet-Mediated Learning

    DEFF Research Database (Denmark)

    Jahnke, Isa; Svendsen, Niels Vandel; Johansen, Simon Kristoffer

    2014-01-01

    learning. We report the gaps and interrelations between the dreams and the practice of the teachers. They dream about an interconnected praxis – the magic silver bullet – and establish their visions of inter- connectivity because of their breakdown experiences of media tablets aiding complexity instead...

  1. Dodging Bullets

    DEFF Research Database (Denmark)

    Witte, Caroline T.; Burger, Martijn J.; Ianchovichina, Elena I.

    2017-01-01

    and geographic constraints on location choice. In the nonresource sector, the least geographically diversified firms are most sensitive to conflict. Other types of political violence, including intermittent violence in the form of terrorist acts and assassinations, or persistent but low-impact events......The relationship between political violence and greenfield foreign direct investment is contingent on the type of violence, the characteristics of the investment-receiving sector, and the international scope of the investing firm. Analysis using a dynamic fixed effects model for a panel of 90...... developing countries shows that nationwide political conflict is negatively associated with total and nonresource-related greenfield FDI, but not with resource-related greenfield FDI. The insensitivity of resource FDI to political conflict is explained by the high profitability of natural-resource extraction...

  2. Modified Johnson–Cook Model-based Numerical Simulation of Small Arms Bullets Penetration in the Aluminum Alloy Plates

    Directory of Open Access Journals (Sweden)

    N. Shash

    2017-01-01

    Full Text Available In this paper, we simulated and studied the penetration process of 7,62 x 63 mm bullets "NATO Ball" (with a soft lead core and 7.62 x 63 mm ones «APM2» (with hard steel core in three kinds of aluminum plates, namely AA5083- H116, AA6082-T4, and AA7075-T6 with three different thicknesses of 10 mm, 20 mm, and 30 mm. The impact velocity was 830 m / s in all tests. Based on the test results and numerical calculations, all plates and a bullet were modeled as the deformable ones with modified constitutive Johnson-Cook relationship and Cockcroft-Latham fracture criterion. Then they were used in modeling by three-dimensional nonlinear finite element in Ansys Ls-Dyna package. The influence of the finite element size in the finite element model on the length and results of calculations has been investigated as well.The main calculation results, we have received, include the residual bullet velocity and the residual kinetic energy of the bullet after drilling a hole in the plate and plate failure mechanism for each type and thickness of the plate with two types of bullets. We have noticed that the residual velocities of the bullets for small thicknesses of aluminum alloys (up to 10 mm have relatively equal values upon penetration of the bullets "NATO Ball" and «APM2» (a bit more, as well as the calculation-obtained failure mechanisms are adequate to experimental. In addition, resistance of AA7075-T651 aluminum alloy to penetration is higher than that of AA5083-H116 and AA6082-T4 ones.It should also be noted that the accuracy of the results depends mainly on the size of the grid elements. The more is the number of elements, the higher is the accuracy of the results, but the longer is the solution time. Therefore, we advice to use the finite element size of 0.2 mm, at most, to obtain the highly accurate results that are adequate to the experimental results.

  3. Inconsistency in 9 mm bullets: correlation of jacket thickness to post-impact geometry measured with non-destructive X-ray computed tomography.

    Science.gov (United States)

    Thornby, John; Landheer, Dirk; Williams, Tim; Barnes-Warden, Jane; Fenne, Paul; Norman, Danielle G; Attridge, Alex; Williams, Mark A

    2014-01-01

    Fundamental to any ballistic armour standard is the reference projectile to be defeated. Typically, for certification purposes, a consistent and symmetrical bullet geometry is assumed, however variations in bullet jacket dimensions can have far reaching consequences. Traditionally, characteristics and internal dimensions have been analysed by physically sectioning bullets--an approach which is of restricted scope and which precludes subsequent ballistic assessment. The use of a non-destructive X-ray computed tomography (CT) method has been demonstrated and validated (Kumar et al., 2011 [15]); the authors now apply this technique to correlate bullet impact response with jacket thickness variations. A set of 20 bullets (9 mm DM11) were selected for comparison and an image-based analysis method was employed to map jacket thickness and determine the centre of gravity of each specimen. Both intra- and inter-bullet variations were investigated, with thickness variations of the order of 200 μm commonly found along the length of all bullets and angular variations of up to 50 μm in some. The bullets were subsequently impacted against a rigid flat plate under controlled conditions (observed on a high-speed video camera) and the resulting deformed projectiles were re-analysed. The results of the experiments demonstrate a marked difference in ballistic performance between bullets from different manufacturers and an asymmetric thinning of the jacket is observed in regions of pre-impact weakness. The conclusions are relevant for future soft armour standards and provide important quantitative data for numerical model correlation and development. The implications of the findings of the work on the reliability and repeatability of the industry standard V50 ballistic test are also discussed. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  4. [Blunt trauma with bullet-proof vests. Skin lesions are no reliable predictor of injury severity].

    Science.gov (United States)

    Doll, D; Illert, B; Bohrer, S; Richter, C; Woelfl, C

    2009-04-01

    It is well known that so-called bullet-proof vests offer protection against a wide range of penetrating trauma, but their protection against blunt trauma is less well understood. Fast projectiles may result in hematomas and contusions behind the armour. We report a traffic accident involving a young soldier wearing a ballistic protection vest resulting in a right thoracoabdominal blunt trauma leading to a confined liver compression rupture. As nearly no skin marks were detectable, we point out that every emergency department surgeon should be very suspicious if a patient wore a ballistic vest at the time of the accident--there may be no skin marks despite severe intra-abdominal trauma. Our patient recovered following hypotensive ICU treatment, thrombocyte mobilization, and factor VIIa substitution.

  5. Numerical Simulations of Light Bullets, Using The Full Vector, Time Dependent, Nonlinear Maxwell Equations

    Science.gov (United States)

    Goorjian, Peter M.; Silberberg, Yaron; Kwak, Dochan (Technical Monitor)

    1995-01-01

    This paper will present results in computational nonlinear optics. An algorithm will be described that solves the full vector nonlinear Maxwell's equations exactly without the approximations that we currently made. Present methods solve a reduced scalar wave equation, namely the nonlinear Schrodinger equation, and neglect the optical carrier. Also, results will be shown of calculations of 2-D electromagnetic nonlinear waves computed by directly integrating in time the nonlinear vector Maxwell's equations. The results will include simulations of 'light bullet' like pulses. Here diffraction and dispersion will be counteracted by nonlinear effects. The time integration efficiently implements linear and nonlinear convolutions for the electric polarization, and can take into account such quantum effects as Karr and Raman interactions. The present approach is robust and should permit modeling 2-D and 3-D optical soliton propagation, scattering, and switching directly from the full-vector Maxwell's equations.

  6. The drone ambulance [A-UAS]: golden bullet or just a blank?

    Science.gov (United States)

    Van de Voorde, P; Gautama, S; Momont, A; Ionescu, C M; De Paepe, P; Fraeyman, N

    2017-07-01

    Defibrillation within the first minutes after sudden cardiac arrest can save many quality-adjusted life years. Yet, despite enormous investments, 'healthcare' is still unable to provide this for the majority of patients. Emergency Medical Services often have a too long mean response time and many issues surround Public Access Defibrillation programs. In this article we argument that AED-equipped drones could be the 'magic bullet'. They are easily deployed and fast, and have a relatively low operational cost. As such they could rapidly bring an AED next to the victim, irrespective of most geographical circumstances, give visual feedback and situational awareness to the EMS dispatcher and thus assist a bystander to provide better CPR. Although there are many real-life barriers to actual deployment, we argument these might all get solved once we have solved the described technological issues. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. NuSTAR observations of the bullet cluster: constraints on inverse compton emission

    DEFF Research Database (Denmark)

    Wik, Daniel R.; Hornstrup, Allan; Molendi, S.

    2014-01-01

    and have degree-scale fields of view, their backgrounds are both high and difficult to characterize. The associated uncertainties result in lower sensitivity to IC emission and a greater chance of false detection. In this work, we present 266 ks NuSTAR observations of the Bullet cluster, which is detected......-but not perfectly-described as an isothermal plasma with kT = 14.2 ± 0.2 keV. To slightly improve the fit, a second temperature component is added, which appears to account for lower temperature emission from the cool core, pushing the primary component to kT ~ 15.3 keV. We see no convincing need to invoke an IC...

  8. Oligo-branched peptides for tumor targeting: from magic bullets to magic forks.

    Science.gov (United States)

    Falciani, Chiara; Pini, Alessandro; Bracci, Luisa

    2009-02-01

    Selective targeting of tumor cells is the final goal of research and drug discovery for cancer diagnosis, imaging and therapy. After the invention of hybridoma technology, the concept of magic bullet was introduced into the field of oncology, referring to selective killing of tumor cells, by specific antibodies. More recently, small molecules and peptides have also been proposed as selective targeting agents. We analyze the state of the art of tumor-selective agents that are presently available and tested in clinical settings. A novel approach based on 'armed' oligo-branched peptides as tumor targeting agents, is discussed and compared with existing tumor-selective therapies mediated by antibodies, small molecules or monomeric peptides. Oligo-branched peptides could be novel drugs that combine the advantages of antibodies and small molecules.

  9. Population Genomics and the Statistical Values of Race:An Interdisciplinary Perspective on the Biological Classification of Human Populations and Implications for Clinical Genetic Epidemiological Research

    Directory of Open Access Journals (Sweden)

    Koffi N. Maglo

    2016-02-01

    Full Text Available The biological status and biomedical significance of the concept of race as applied to humans continue to be contentious issues despite the use of advanced statistical and clustering methods to determine continental ancestry. It is thus imperative for researchers to understand the limitations as well as potential uses of the concept of race in biology and biomedicine. This paper deals with the theoretical assumptions behind cluster analysis in human population genomics. Adopting an interdisciplinary approach, it demonstrates that the hypothesis that attributes the clustering of human populations to frictional effects of landform barriers at continental boundaries is empirically incoherent. It then contrasts the scientific status of the cluster and cline constructs in human population genomics, and shows how cluster may be instrumentally produced. It also shows how statistical values of race vindicate Darwin’s argument that race is evolutionarily meaningless. Finally, the paper explains why, due to spatiotemporal parameters, evolutionary forces and socio-cultural factors influencing population structure, continental ancestry may be pragmatically relevant to global and public health genomics. Overall, this work demonstrates that, from a biological systematic and evolutionary taxonomical perspective, human races/continental groups or clusters have no natural meaning or objective biological reality. In fact, the utility of racial categorizations in research and in clinics can be explained by spatiotemporal parameters, socio-cultural factors and evolutionary forces affecting disease causation and treatment response.

  10. SPORT FOOD ADDITIVE CLASSIFICATION

    Directory of Open Access Journals (Sweden)

    I. P. Prokopenko

    2015-01-01

    Full Text Available Correctly organized nutritive and pharmacological support is an important component of an athlete's preparation for competitions, an optimal shape maintenance, fast recovery and rehabilitation after traumas and defatigation. Special products of enhanced biological value (BAS for athletes nutrition are used with this purpose. Easy-to-use energy sources are administered into athlete's organism, yielded materials and biologically active substances which regulate and activate exchange reactions which proceed with difficulties during certain physical trainings. The article presents sport supplements classification which can be used before warm-up and trainings, after trainings and in competitions breaks.

  11. Terminal Performance of Lead Free Pistol Bullets in Ballistic Gelatin Using Retarding Force Analysis from High Speed Video

    Science.gov (United States)

    2016-04-04

    acceleration can be calculated. The change in kinetic energy can also be computed. In the video, temporary and permanent cavities are also visible. In this...notable that the video method above also allows the energy deposited as a funtion of penetration depth to be computed, when velocity is expressed...deposit as a function of penetration depth. The approach in this study employs the energy lost by the bullet in the first 15 cm of penetration , E15

  12. Tissue Classification

    DEFF Research Database (Denmark)

    Van Leemput, Koen; Puonti, Oula

    2015-01-01

    Computational methods for automatically segmenting magnetic resonance images of the brain have seen tremendous advances in recent years. So-called tissue classification techniques, aimed at extracting the three main brain tissue classes (white matter, gray matter, and cerebrospinal fluid), are now...... well established. In their simplest form, these methods classify voxels independently based on their intensity alone, although much more sophisticated models are typically used in practice. This article aims to give an overview of often-used computational techniques for brain tissue classification...

  13. A model for beta skin dose estimation due to the use of a necklace with uranium depleted bullets

    International Nuclear Information System (INIS)

    Lavalle Heibron, P.H.; Pérez Guerrero, J.S.; Oliveira, J.F. de

    2015-01-01

    Depleted uranium bullets were use as munitions during the Kuwait – Iraq war and the International Atomic Energy Agency sampling expert’s team found fragments in the environment when the war was over. Consequently, there is a possibility that members of the public, especially children, collects DU fragments and use it, for example, to make a necklace. This paper estimates the beta skin dose to a child that uses a necklace made with a depleted uranium bullet. The theoretical model for dose estimation is based on Loevinguer’s equation with a correction factor adjusted for the maximum beta energy in the range between 0.1 and 2.5 MeV calculated taking into account the International Atomic Energy Agency expected doses rates in air at one meter distance of a point source of 37 GBq, function of the maximum beta energy. The dose rate estimated by this work due to the child use of a necklace with one depleted uranium bullet of 300 g was in good agreement with other results founded in literature. (authors)

  14. Bullet embolization to the external iliac artery after gunshot injury to the abdominal aorta: a case report

    Directory of Open Access Journals (Sweden)

    Jaha Luan

    2011-08-01

    Full Text Available Abstract Introduction Abdominal vascular trauma is fairly common in modern civilian life and is a highly lethal injury. However, if the projectile is small enough, if its energy is diminished when passing through the tissue and if the arterial system is elastic enough, the entry wound into the artery may close without exsanguination and therefore may not be fatal. A projectile captured may even travel downstream until it is arrested by the smaller distal vasculature. The occurrence of this phenomenon is rare and was first described by Trimble in 1968. Case presentation Here we present a case of a 29-year-old Albanian man who, due to a gunshot injury to the back, suffered fracture of his twelfth thoracic and first lumbar vertebra, injury to the posterior wall of his abdominal aorta and then bullet embolism to his left external iliac artery. It is interesting that the signs of distal ischemia developed several hours after the exploratory surgery, raising the possibility that the bullet migrated in the interim or that there was a failure to recognize it during the exploratory surgery. Conclusion In all cases where there is a gunshot injury to the abdomen or chest without an exit wound and with no projectile in the area, there should be a high index of suspicion for possible bullet embolism, particularly in the presence of the distal ischemia.

  15. Fixation Strength of Polyetheretherketone Sheath-and-Bullet Device for Soft Tissue Repair in the Foot and Ankle.

    Science.gov (United States)

    Christensen, Jay; Fischer, Brian; Nute, Michael; Rizza, Robert

    Tendon transfers are often performed in the foot and ankle. Recently, interference screws have been a popular choice owing to their ease of use and fixation strength. Considering the benefits, one disadvantage of such devices is laceration of the soft tissues by the implant threads during placement that potentially weaken the structural integrity of the grafts. A shape memory polyetheretherketone bullet-in-sheath tenodesis device uses circumferential compression, eliminating potential damage from thread rotation and maintaining the soft tissue orientation of the graft. The aim of this study was to determine the pullout strength and failure mode for this device in both a synthetic bone analogue and porcine bone models. Thirteen mature bovine extensor tendons were secured into ten 4.0 × 4.0 × 4.0-cm cubes of 15-pound per cubic foot solid rigid polyurethane foam bone analogue models or 3 porcine femoral condyles using the 5 × 20-mm polyetheretherketone soft tissue anchor. The bullet-in-sheath device demonstrated a mean pullout of 280.84 N in the bone analog models and 419.47 N in the porcine bone models. (p = .001). The bullet-in-sheath design preserved the integrity of the tendon graft, and none of the implants dislodged from their original position. Copyright © 2017 The American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

  16. Two bullets to the head and an early winter: fate permits Kutuzov to defeat Napoleon at Moscow.

    Science.gov (United States)

    Kushchayev, Sergiy V; Belykh, Evgenii; Fishchenko, Yakiv; Salei, Aliaksei; Teytelboym, Oleg M; Shabaturov, Leonid; Cruse, Mark; Preul, Mark C

    2015-07-01

    General Mikhail Kutuzov (circa 1745-1813) brilliantly repelled Napoleon's invasion of Russia. Honored as a national hero and a savior of Russia, Kutuzov has a unique medical story. He was shot in the head twice while fighting the Turks (1774 and 1788) and survived the serious injuries seemingly against all odds. The first bullet "ran through the head from one temple to the other behind both eyes." The second bullet entered the cheek, destroyed upper teeth, traveled through the head, and exited the occiput. Massot, a French surgeon with the Russian army, wrote after treating Kutuzov's seemingly two mortal wounds: "It must be believed that fate appoints Kutuzov to something great, because he was still alive after two injuries, a death sentence by all the rules of medical science." Aided by Massot's expert surgical technique, Kutuzov lived to become intimately engaged in events that altered world history. His health did, however, suffer significant effects due to the bullet wounds. In 1812, as Napoleon's Grande Armée approached, Kutuzov realized he could not confront Napoleon and he strategically retreated from Moscow, submitting the French to the harsh winter and Russian cavalry. Napoleon's devastated army retreated to Paris, and Kutuzov became the personification of Russian spirit and character. Kutuzov's survival of two nearly mortal head wounds created the legends, additional mystery, and drama surrounding him, not the least astonishing of which was the skilled neurosurgical care that probably saved his life.

  17. Ferromagnetic behavior in linear charge-transfer complexes. Structural and magnetic characterization of octamethylferrocene salts: (Fe(C sub 5 Me sub 4 H) sub 2 ) sup sm bullet + (A) sup sm bullet minus (A = TCNE, TCNQ)

    Energy Technology Data Exchange (ETDEWEB)

    Miller, J.S.; Glatzhofer, D.T.; O' Hare, D.M. (E.I. de Pont de Nemours and Co., Inc., Wilmington, DE (USA)); Reiff, W.M. (Northeastern Univ., Boston, MA (USA)); Chakraborty, A.; Epstein, A.J. (Ohio Sate Univ., Columbus (USA))

    1989-07-26

    The reaction of Fe{sup II}({eta}{sup 5}-C{sub 5}Me{sub 4}H){sub 2} with cyano acceptors A (A = TCNE (tetracyanoethylene), TCNQ (7,7,8,8-tetracyano-p-quanodimethane), n-C{sub 4}(CN){sub 6} (n-hexacyanobutadiene), C{sub 6}(CN){sub 6} (tris(dicyanomethylene)cyclopropane), DDQ (2,3-dichloro-5,6-dicyanobenzoquinone), TCNQF{sub 4} (perfluoro-7,7,8,8-tetracyano-p-quinodimethane) results in formation of 1:1 charge-transfer salts of (Fe{sup III})(C{sub 5}Me{sub 4}H){sub 2}){sup {sm bullet}+}(A){sup {sm bullet}{minus}} composition. The TCNE and TCNQ complexes have been structurally characterized. The high-temperature magnetic susceptibility for polycrystalline samples of these complexes can be fit by the Curie-Qeiss law, {chi} = C(T-{theta}){sup {minus}1}, with {theta} = +0.5 {plus minus} 2.2 K, and {mu}{sub eff} ranges from 2.71 to 3.97 {mu}{sub B}, suggesting that the polycrystalline samples measured had varying degrees of orientation. The 7.0 K EPR spectrum of the radical cation exhibits an axially symmetric powder pattern with g{sub {parallel}} = 4.11 and g{sub {perpendicular}} = 1.42, and the EPR parameters are essentially identical with those reported for ferrocenium and decamethylferrocenium. No EPR spectrum is observed at 78 K. Akin to the (Fe(C{sub 5}Me{sub 5}){sub 2}){sup {sm bullet}+} salts, these salts have {sup 57}Fe Moessbauer spectra consistent with complete charge transfer; however, unlike the case for the former complexes, quadrupole splittings of 0.30 and 0.220 mm/s are observed at 4.8 and 298 K, respectively. The absence of strong interionic magnetic coupling for the (Fe(C{sub 5}Me{sub 4}H){sub 2}){sup {sm bullet}+} salts contrasts with the behavior of the (Fe(C{sub 5}Me{sub 5}){sub 2}){sup {sm bullet}+} salts. 26 refs., 13 figs., 8 tabs.

  18. Bullet scintigraphy: can gamma camera be used for depleted uranium accident measurements?

    International Nuclear Information System (INIS)

    Spaic, R.; Markovic, S.; Pavlovic, S.; Radic, Z.; Pavlovic, R.; Ajdinovic, B.; Baskot, B.; Djurovic, B.

    2002-01-01

    The aim of this study was to see could gamma cameras be used for measurement of internal contamination with depleted uranium. Radioactive waste depleted uranium, which is by-product from the production of enriched fuel for nuclear rectors and weapons now, is used for manufacture bullets, which are used in Iraq, Republic of Srpska and Yugoslavia. In this paper is measured minimum detectable activity (MDA) of gamma cameras for depleted uranium, iodine and technetium. For detection of the depleted uranium are used low energy X-rays, energy of 100 keV with 20% windows width. About 40% of gamma emissions of the depleted uranium are in these limits. Measured MDA activities 50-100 Bq for depleted uranium, iodine and technetium are about then times more then same for WBC (5 Bq). Gamma cameras can be used for relatively measurement of depleted uranium activity, what can be used for absorbed dose estimation. Detection of low level internal contamination with depleted uranium can be done with gamma cameras. (authors)

  19. Scape goats, silver bullets, and other pitfalls in the path to sustainability

    Directory of Open Access Journals (Sweden)

    D. G. Webster

    2017-03-01

    Full Text Available This paper draws from 'The Lathe of Heaven' by Ursula Le Guin to highlight some of the most likely pitfalls on the political road to a sustainable planet. Through the literary device of dreams that can change the world, Le Guin explores how the individual’s egoistic desire to save humanity can be twisted by the limitations of our psyche and our society, turning an already uncomfortable future Earth into a devastated planet. It is a stinging critique of answers handed down from above, and a call to action for those of us who just get by here below. Her story warns of the ancient “road to hell”, paved and trodden by would be saviors with the best intentions but also points to the license that public apathy provides to the powerful when the costs of environmental harm are borne by the powerless. These disconnects, combined with cycles of rationalization, silver bullet mentalities, and the tendency to scapegoat others for negative side effects, can all derail sustainability transitions. 'Lathe' provides an allegorical assessment of this process, but much more study is needed to fully understand and regulate the resulting governance treadmill.

  20. Simulation of white light generation and near light bullets using a novel numerical technique

    Science.gov (United States)

    Zia, Haider

    2018-01-01

    An accurate and efficient simulation has been devised, employing a new numerical technique to simulate the derivative generalised non-linear Schrödinger equation in all three spatial dimensions and time. The simulation models all pertinent effects such as self-steepening and plasma for the non-linear propagation of ultrafast optical radiation in bulk material. Simulation results are compared to published experimental spectral data of an example ytterbium aluminum garnet system at 3.1 μm radiation and fits to within a factor of 5. The simulation shows that there is a stability point near the end of the 2 mm crystal where a quasi-light bullet (spatial temporal soliton) is present. Within this region, the pulse is collimated at a reduced diameter (factor of ∼2) and there exists a near temporal soliton at the spatial center. The temporal intensity within this stable region is compressed by a factor of ∼4 compared to the input. This study shows that the simulation highlights new physical phenomena based on the interplay of various linear, non-linear and plasma effects that go beyond the experiment and is thus integral to achieving accurate designs of white light generation systems for optical applications. An adaptive error reduction algorithm tailor made for this simulation will also be presented in appendix.

  1. Manufacturing immunity to disease in a test tube: the magic bullet realized.

    Science.gov (United States)

    Lerner, Richard A

    2006-12-11

    Although it took over one hundred years, Ehrlich's concept of the magic bullet is now a reality. Today, therapeutic antibodies are, arguably, the most important class of new drugs for the treatment of illnesses ranging from Alzheimer's disease to cancer. The emergence of therapeutic antibodies had to wait for advances in immunochemistry that allowed construction of antibodies in vitro. The centerpiece of the new technology is the combinatorial antibody library, which essentially allows one to synthesize an artificial immune system with a diversity that exceeds that of the natural repertoire. The construction of such libraries was perceived to be difficult because, if the natural immune system was to be used as the starting material, construction of the libraries would entail protocols that are the opposite of usual cloning. In gene cloning one starts with complexity and reduces it to a singularity. In the generation of diversity by construction of combinatorial antibody libraries, one starts with a collection of clones, randomly expands their complexity, and then returns them to recoverable singularities. The methods developed to accomplish this seemingly formidable task now allow construction of antibodies in a test tube to any antigen. These synthetic antibodies may be qualitatively and quantitatively superior to those of nature.

  2. Transporter Classification Database (TCDB)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Transporter Classification Database details a comprehensive classification system for membrane transport proteins known as the Transporter Classification (TC)...

  3. Differential Classification of Dementia

    Directory of Open Access Journals (Sweden)

    E. Mohr

    1995-01-01

    Full Text Available In the absence of biological markers, dementia classification remains complex both in terms of characterization as well as early detection of the presence or absence of dementing symptoms, particularly in diseases with possible secondary dementia. An empirical, statistical approach using neuropsychological measures was therefore developed to distinguish demented from non-demented patients and to identify differential patterns of cognitive dysfunction in neurodegenerative disease. Age-scaled neurobehavioral test results (Wechsler Adult Intelligence Scale—Revised and Wechsler Memory Scale from Alzheimer's (AD and Huntington's (HD patients, matched for intellectual disability, as well as normal controls were used to derive a classification formula. Stepwise discriminant analysis accurately (99% correct distinguished controls from demented patients, and separated the two patient groups (79% correct. Variables discriminating between HD and AD patient groups consisted of complex psychomotor tasks, visuospatial function, attention and memory. The reliability of the classification formula was demonstrated with a new, independent sample of AD and HD patients which yielded virtually identical results (classification accuracy for dementia: 96%; AD versus HD: 78%. To validate the formula, the discriminant function was applied to Parkinson's (PD patients, 38% of whom were classified as demented. The validity of the classification was demonstrated by significant PD subgroup differences on measures of dementia not included in the discriminant function. Moreover, a majority of demented PD patients (65% were classified as having an HD-like pattern of cognitive deficits, in line with previous reports of the subcortical nature of PD dementia. This approach may thus be useful in classifying presence or absence of dementia and in discriminating between dementia subtypes in cases of secondary or coincidental dementia.

  4. Molecular Classification and Correlates in Colorectal Cancer

    OpenAIRE

    Ogino, Shuji; Goel, Ajay

    2008-01-01

    Molecular classification of colorectal cancer is evolving. As our understanding of colorectal carcinogenesis improves, we are incorporating new knowledge into the classification system. In particular, global genomic status [microsatellite instability (MSI) status and chromosomal instability (CIN) status] and epigenomic status [CpG island methylator phenotype (CIMP) status] play a significant role in determining clinical, pathological and biological characteristics of colorectal cancer. In thi...

  5. Introduction to Classification of Living Things.

    Science.gov (United States)

    Stettler, Donald

    This monograph contains an autoinstructional packet developed for secondary school biology students. The instructions present a lesson on classification using slides and packets of pictures as the media for displaying the animals and plants to be classified. A brief historical account leads into the study of the modern classification system. No…

  6. Direction, site and the muzzle target distance of bullet in the head and neck at close range as an indication of suicide or homicide.

    Science.gov (United States)

    Suwanjutha, T

    1988-05-01

    Direction, site and muzzle target distance can indicate suicide or homicide. This conclusion can be drawn from autopsies of 57 cases of suicide and 68 cases of homicide by handgun fired at close range to the head and neck together with going to the crimescene in some cases. This study was carried out in Bangkok during the period from January 1983 to January 1986. In order to determine whether it was suicide or homicide, the path of the bullet, the site, the muzzle target distance must be considered. The angle of the bullet would be either elevated (from below upward), horizontal or an angle of depression (from above downward). For suicide, the direction of the bullet should be at an angle of elevation in the majority of cases. The position of the handgun in relation to the head in suicide was most often in tight contact and near contact. For homicide, the direction of the bullet should be horizontal in most cases. The bullet was at close range in the majority of the cases. There are 8 common sites for suicide and homicide and 10 different sites in the case of homicide which are at neck, left cheek, left aural region, lip, left occipital area orbit, chin, left eyebrow, submental and nose.

  7. The virtual double-slit experiment to High School level (Part I: behavior classical analysis (with bullets and waves and development of computational software

    Directory of Open Access Journals (Sweden)

    Danilo Cardoso Ferreira

    2016-09-01

    Full Text Available http://dx.doi.org/10.5007/2175-7941.2016v33n2p697   This paper analyses the double-slit virtual experiment and it composed of two parts: The part I covers the classical theory (with bullets and waves and the part II covers the interference with electrons or photons. Firstly, we have analyzed the same experiment that shoots a stream of bullets. In front of the gun we have a wall that has in it two holes just big enough to let a bullet through. Beyond the wall is a backstop (say a thick wall of wood which will absorb the bullets when they hit it. In this case, the probabilities just add together. The effect with both holes open is the sum of effects with each holes open alone. We have shown it for high school level. Next, we have analyzed a same experiment with water waves. The intensity observed when both holes are open is certainly not the sum of the intensity of the wave from hole 1 (which we find by measuring when hole 2 is blocked off and the intensity of the wave form hole 2 (seen when hole 1 is blocked. Finally, we have shown a software developed by students about double-slit experiment with bullets.

  8. Abordagem terapêutica dos projéteis retidos no coração Management of bullets lodged in the heart

    Directory of Open Access Journals (Sweden)

    Enoch Brandão de Souza Meira

    2005-03-01

    Full Text Available Paciente do sexo masculino, 29 anos, apresentando ferimento por arma de fogo, com projétil alojado no coração e que chegou ao hospital hemodinamicamente estável. O diagnóstico, evidenciando a localização da bala, foi feito pelo ecocardiograma transesofágico (ET. Após 18 dias, foi submetido à cirurgia eletiva, sem circulação extracorpórea (CEC, para retirada do projétil encravado em parede anterior do ventrículo direito (VD e septo interventricular (SIV, com sucesso. Os autores discutem a conduta terapêutica para os projéteis retidos no coração, com base na literatura consultada, concluindo que a cirurgia para remoção dos mesmos pode ser indicada em pacientes assintomáticos individualizados.A 29-year-old man presented with a bullet lodged in his heart. He arrived at the hospital in a hemodynamically stable condition. The transesophageal echocardiogram performed for diagnosis revealed the location of the bullet. After 18 days, he underwent an elective off-pump cardiac surgery fto remove the bullet from the right ventricle wall and interventricular septum. The postoperative evolution was uneventful. The authors discuss the therapeutic options for removing bullets from thr heart, based on published data. They concluded that some asymptomatic patients with a bullet embedded in the heart should undergo surgery.

  9. INNOVATION IN ACCOUNTING BIOLOGIC ASSETS

    OpenAIRE

    Stolуarova M. A.; Shcherbina I. D.

    2016-01-01

    The article describes the innovations in the classification and measurement of biological assets according to IFRS (IAS) 41 "Agriculture". The difficulties faced by agricultural producers using standard, set out in article. The classification based on the adopted amendments, according to which the fruit-bearing plants, previously accounted for as biological assets are measured at fair value are included in the category of fixed assets. The structure of biological assets and main means has bee...

  10. SPECTROSCOPIC CONFIRMATION OF A z = 6.740 GALAXY BEHIND THE BULLET CLUSTER

    Energy Technology Data Exchange (ETDEWEB)

    Bradac, Marusa; Hall, Nicholas [Department of Physics, University of California, Davis, CA 95616 (United States); Vanzella, Eros [INAF, Osservatorio Astronomico di Trieste, via G.B. Tiepolo 11, 34131 Trieste (Italy); Treu, Tommaso [Department of Physics, University of California, Santa Barbara, CA 93106 (United States); Fontana, Adriano [INAF, Osservatorio Astronomico di Roma, via Frascati 33, 00040 Monteporzio (Italy); Gonzalez, Anthony H. [Department of Astronomy, University of Florida, 211 Bryant Space Science Center, Gainesville, FL 32611 (United States); Clowe, Douglas [Department of Physics and Astronomy, Ohio University, Clippinger Labs 251B, Athens, OH 45701 (United States); Zaritsky, Dennis; Clement, Benjamin [Steward Observatory, University of Arizona, 933 N Cherry Ave., Tucson, AZ 85721 (United States); Stiavelli, Massimo, E-mail: marusa@physics.ucdavis.edu [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States)

    2012-08-10

    We present the first results of our spectroscopic follow-up of 6.5 < z < 10 candidate galaxies behind clusters of galaxies. We report the spectroscopic confirmation of an intrinsically faint Lyman break galaxy (LBG) identified as a z{sub 850LP}-band dropout behind the Bullet Cluster. We detect an emission line at {lambda} = 9412 A at >5{sigma} significance using a 16 hr long exposure with FORS2 VLT. Based on the absence of flux in bluer broadband filters, the blue color of the source, and the absence of additional lines, we identify the line as Ly{alpha} at z = 6.740 {+-} 0.003. The integrated line flux is f = (0.7 {+-} 0.1 {+-} 0.3) Multiplication-Sign 10{sup -17} erg{sup -1} s{sup -1} cm{sup -2} (the uncertainties are due to random and flux calibration errors, respectively) making it the faintest Ly{alpha} flux detected at these redshifts. Given the magnification of {mu} = 3.0 {+-} 0.2 the intrinsic (corrected for lensing) flux is f {sup int} = (0.23 {+-} 0.03 {+-} 0.10 {+-} 0.02) Multiplication-Sign 10{sup -17} erg{sup -1} s{sup -1} cm{sup -2} (additional uncertainty due to magnification), which is {approx}2-3 times fainter than other such measurements in z {approx} 7 galaxies. The intrinsic H{sub 160W}-band magnitude of the object is m{sup int}{sub H{sub 1{sub 6{sub 0{sub W}}}}}=27.57{+-}0.17, corresponding to 0.5 L* for LBGs at these redshifts. The galaxy is one of the two sub-L* LBG galaxies spectroscopically confirmed at these high redshifts (the other is also a lensed z = 7.045 galaxy), making it a valuable probe for the neutral hydrogen fraction in the early universe.

  11. On non-equilibrium atmospheric pressure plasma jets and plasma bullet

    Science.gov (United States)

    Lu, Xinpei

    2012-10-01

    Because of the enhanced plasma chemistry, atmospheric pressure nonequilibrium plasmas (APNPs) have been widely studied for several emerging applications such as biomedical applications. For the biomedical applications, plasma jet devices, which generate plasma in open space (surrounding air) rather than in confined discharge gaps only, have lots of advantages over the traditional dielectric barrier discharge (DBD) devices. For example, it can be used for root canal disinfection, which can't be realized by the traditional plasma device. On the other hand, currently, the working gases of most of the plasma jet devices are noble gases or the mixtures of the noble gases with small amount of O2, or air. If ambient air is used as the working gas, several serious difficulties are encountered in the plasma generation process. Amongst these are high gas temperatures and disrupting instabilities. In this presentation, firstly, a brief review of the different cold plasma jets developed to date is presented. Secondly, several different plasma jet devices developed in our lab are reported. The effects of various parameters on the plasma jets are discussed. Finally, one of the most interesting phenomena of APNP-Js, the plasma bullet is discussed and its behavior is described. References: [1] X. Lu, M. Laroussi, V. Puech, Plasma Sources Sci. Technol. 21, 034005 (2012); [2] Y. Xian, X. Lu, S. Wu, P. Chu, and Y. Pan, Appl. Phys. Lett. 100, 123702 (2012); [3] X. Pei, X. Lu, J. Liu, D. Liu, Y. Yang, K. Ostrikov, P. Chu, and Y. Pan, J. Phys. D 45, 165205 (2012).

  12. Another shock for the Bullet cluster, and the source of seed electrons for radio relics

    Science.gov (United States)

    Shimwell, Timothy W.; Markevitch, Maxim; Brown, Shea; Feretti, Luigina; Gaensler, B. M.; Johnston-Hollitt, M.; Lage, Craig; Srinivasan, Raghav

    2015-05-01

    With Australia Telescope Compact Array observations, we detect a highly elongated Mpc-scale diffuse radio source on the eastern periphery of the Bullet cluster 1E 0657-55.8, which we argue has the positional, spectral and polarimetric characteristics of a radio relic. This powerful relic (2.3 ± 0.1 × 1025 W Hz-1) consists of a bright northern bulb and a faint linear tail. The bulb emits 94 per cent of the observed radio flux and has the highest surface brightness of any known relic. Exactly coincident with the linear tail, we find a sharp X-ray surface brightness edge in the deep Chandra image of the cluster - a signature of a shock front in the hot intracluster medium (ICM), located on the opposite side of the cluster to the famous bow shock. This new example of an X-ray shock coincident with a relic further supports the hypothesis that shocks in the outer regions of clusters can form relics via diffusive shock (re-)acceleration. Intriguingly, our new relic suggests that seed electrons for reacceleration are coming from a local remnant of a radio galaxy, which we are lucky to catch before its complete disruption. If this scenario, in which a relic forms when a shock crosses a well-defined region of the ICM polluted with aged relativistic plasma - as opposed to the usual assumption that seeds are uniformly mixed in the ICM - is also the case for other relics, this may explain a number of peculiar properties of peripheral relics.

  13. Classifications of track structures

    International Nuclear Information System (INIS)

    Paretzke, H.G.

    1984-01-01

    When ionizing particles interact with matter they produce random topological structures of primary activations which represent the initial boundary conditions for all subsequent physical, chemical and/or biological reactions. There are two important aspects of research on such track structures, namely their experimental or theoretical determination on one hand and the quantitative classification of these complex structures which is a basic pre-requisite for the understanding of mechanisms of radiation actions. This paper deals only with the latter topic, i.e. the problems encountered in and possible approaches to quantitative ordering and grouping of these multidimensional objects by their degrees of similarity with respect to their efficiency in producing certain final radiation effects, i.e. to their ''radiation quality.'' Various attempts of taxonometric classification with respect to radiation efficiency have been made in basic and applied radiation research including macro- and microdosimetric concepts as well as track entities and stopping power based theories. In this paper no review of those well-known approaches is given but rather an outline and discussion of alternative methods new to this field of radiation research which have some very promising features and which could possibly solve at least some major classification problems

  14. Combat-related intradural gunshot wound to the thoracic spine: significant improvement and neurologic recovery following bullet removal.

    Science.gov (United States)

    Louwes, Thijs M; Ward, William H; Lee, Kendall H; Freedman, Brett A

    2015-02-01

    The vast majority of combat-related penetrating spinal injuries from gunshot wounds result in severe or complete neurological deficit. Treatment is based on neurological status, the presence of cerebrospinal fluid (CSF) fistulas, and local effects of any retained fragment(s). We present a case of a 46-year-old male who sustained a spinal gunshot injury from a 7.62-mm AK-47 round that became lodged within the subarachnoid space at T9-T10. He immediately suffered complete motor and sensory loss. By 24-48 hours post-injury, he had recovered lower extremity motor function fully but continued to have severe sensory loss (posterior cord syndrome). On post-injury day 2, he was evacuated from the combat theater and underwent a T9 laminectomy, extraction of the bullet, and dural laceration repair. At surgery, the traumatic durotomy was widened and the bullet, which was laying on the dorsal surface of the spinal cord, was removed. The dura was closed in a water-tight fashion and fibrin glue was applied. Postoperatively, the patient made a significant but incomplete neurological recovery. His stocking-pattern numbness and sub-umbilical searing dysthesia improved. The spinal canal was clear of the foreign body and he had no persistent CSF leak. Postoperative magnetic resonance imaging of the spine revealed contusion of the spinal cord at the T9 level. Early removal of an intra-canicular bullet in the setting of an incomplete spinal cord injury can lead to significant neurological recovery following even high-velocity and/or high-caliber gunshot wounds. However, this case does not speak to, and prior experience does not demonstrate, significant neurological benefit in the setting of a complete injury.

  15. Potential Hazard to Human Health from Exposure to Fragments of Lead Bullets and Shot in the Tissues of Game Animals

    Science.gov (United States)

    Pain, Deborah J.; Cromie, Ruth L.; Newth, Julia; Brown, Martin J.; Crutcher, Eric; Hardman, Pippa; Hurst, Louise; Mateo, Rafael; Meharg, Andrew A.; Moran, Annette C.; Raab, Andrea; Taggart, Mark A.; Green, Rhys E.

    2010-01-01

    Background Lead is highly toxic to animals. Humans eating game killed using lead ammunition generally avoid swallowing shot or bullets and dietary lead exposure from this source has been considered low. Recent evidence illustrates that lead bullets fragment on impact, leaving small lead particles widely distributed in game tissues. Our paper asks whether lead gunshot pellets also fragment upon impact, and whether lead derived from spent gunshot and bullets in the tissues of game animals could pose a threat to human health. Methodology/Principal Findings Wild-shot gamebirds (6 species) obtained in the UK were X-rayed to determine the number of shot and shot fragments present, and cooked using typical methods. Shot were then removed to simulate realistic practice before consumption, and lead concentrations determined. Data from the Veterinary Medicines Directorate Statutory Surveillance Programme documenting lead levels in raw tissues of wild gamebirds and deer, without shot being removed, are also presented. Gamebirds containing ≥5 shot had high tissue lead concentrations, but some with fewer or no shot also had high lead concentrations, confirming X-ray results indicating that small lead fragments remain in the flesh of birds even when the shot exits the body. A high proportion of samples from both surveys had lead concentrations exceeding the European Union Maximum Level of 100 ppb w.w. (0.1 mg kg−1 w.w.) for meat from bovine animals, sheep, pigs and poultry (no level is set for game meat), some by several orders of magnitude. High, but feasible, levels of consumption of some species could result in the current FAO/WHO Provisional Weekly Tolerable Intake of lead being exceeded. Conclusions/Significance The potential health hazard from lead ingested in the meat of game animals may be larger than previous risk assessments indicated, especially for vulnerable groups, such as children, and those consuming large amounts of game. PMID:20436670

  16. Potential hazard to human health from exposure to fragments of lead bullets and shot in the tissues of game animals.

    Directory of Open Access Journals (Sweden)

    Deborah J Pain

    Full Text Available BACKGROUND: Lead is highly toxic to animals. Humans eating game killed using lead ammunition generally avoid swallowing shot or bullets and dietary lead exposure from this source has been considered low. Recent evidence illustrates that lead bullets fragment on impact, leaving small lead particles widely distributed in game tissues. Our paper asks whether lead gunshot pellets also fragment upon impact, and whether lead derived from spent gunshot and bullets in the tissues of game animals could pose a threat to human health. METHODOLOGY/PRINCIPAL FINDINGS: Wild-shot gamebirds (6 species obtained in the UK were X-rayed to determine the number of shot and shot fragments present, and cooked using typical methods. Shot were then removed to simulate realistic practice before consumption, and lead concentrations determined. Data from the Veterinary Medicines Directorate Statutory Surveillance Programme documenting lead levels in raw tissues of wild gamebirds and deer, without shot being removed, are also presented. Gamebirds containing > or =5 shot had high tissue lead concentrations, but some with fewer or no shot also had high lead concentrations, confirming X-ray results indicating that small lead fragments remain in the flesh of birds even when the shot exits the body. A high proportion of samples from both surveys had lead concentrations exceeding the European Union Maximum Level of 100 ppb w.w. (0.1 mg kg(-1 w.w. for meat from bovine animals, sheep, pigs and poultry (no level is set for game meat, some by several orders of magnitude. High, but feasible, levels of consumption of some species could result in the current FAO/WHO Provisional Weekly Tolerable Intake of lead being exceeded. CONCLUSIONS/SIGNIFICANCE: The potential health hazard from lead ingested in the meat of game animals may be larger than previous risk assessments indicated, especially for vulnerable groups, such as children, and those consuming large amounts of game.

  17. Potential hazard to human health from exposure to fragments of lead bullets and shot in the tissues of game animals.

    Science.gov (United States)

    Pain, Deborah J; Cromie, Ruth L; Newth, Julia; Brown, Martin J; Crutcher, Eric; Hardman, Pippa; Hurst, Louise; Mateo, Rafael; Meharg, Andrew A; Moran, Annette C; Raab, Andrea; Taggart, Mark A; Green, Rhys E

    2010-04-26

    Lead is highly toxic to animals. Humans eating game killed using lead ammunition generally avoid swallowing shot or bullets and dietary lead exposure from this source has been considered low. Recent evidence illustrates that lead bullets fragment on impact, leaving small lead particles widely distributed in game tissues. Our paper asks whether lead gunshot pellets also fragment upon impact, and whether lead derived from spent gunshot and bullets in the tissues of game animals could pose a threat to human health. Wild-shot gamebirds (6 species) obtained in the UK were X-rayed to determine the number of shot and shot fragments present, and cooked using typical methods. Shot were then removed to simulate realistic practice before consumption, and lead concentrations determined. Data from the Veterinary Medicines Directorate Statutory Surveillance Programme documenting lead levels in raw tissues of wild gamebirds and deer, without shot being removed, are also presented. Gamebirds containing > or =5 shot had high tissue lead concentrations, but some with fewer or no shot also had high lead concentrations, confirming X-ray results indicating that small lead fragments remain in the flesh of birds even when the shot exits the body. A high proportion of samples from both surveys had lead concentrations exceeding the European Union Maximum Level of 100 ppb w.w. (0.1 mg kg(-1) w.w.) for meat from bovine animals, sheep, pigs and poultry (no level is set for game meat), some by several orders of magnitude. High, but feasible, levels of consumption of some species could result in the current FAO/WHO Provisional Weekly Tolerable Intake of lead being exceeded. The potential health hazard from lead ingested in the meat of game animals may be larger than previous risk assessments indicated, especially for vulnerable groups, such as children, and those consuming large amounts of game.

  18. Direct measuring of single-cycle mid-IR light bullets path length in LiF by the laser coloration method

    Directory of Open Access Journals (Sweden)

    Chekalin Sergey

    2017-01-01

    Full Text Available A colour-centre structure formed in a LiF crystal under filamentation of a femtosecond mid-IR laser pulse with a power slightly exceeding the critical power for self-focusing has been experimentally and theoretically investigated. A single-cycle light bullet was recorded for the first time by observation of strictly periodic oscillations for the density of the color centers induced in an isotropic LiF crystal under filamentation of a laser beam with a wavelength tuned in the range from 2600 to 3900 nm, which is due to the periodic change in the light field amplitude in the light bullet formed under filamentation under propagation in dispersive medium. The light bullet path length was not more than one millimeter.

  19. Atypical gunshot injury to the right side of the face with the bullet lodged in the carotid sheath: a case report.

    Science.gov (United States)

    Ongom, Peter A; Kijjambu, Stephen C; Jombwe, Josephat

    2014-01-27

    Gunshot injuries of the head and neck from the AK-47 rifle (a common assault rifle, submachine gun type) are a significant contributor to morbidity and mortality among civilians in Sub-Saharan Africa. They may cause significant damage to the closely arranged structures in this region, and the bullet's trajectory can be very difficult to determine. We present an unusual case of gunshot injury with an atypical bullet entry wound, profound injury to the face, lodgment in the right carotid sheath, and 'wandering'; a first of its kind in East Africa. A 27-year-old African-Ugandan woman of Nilotic ethnicity was referred to the Accident and Emergency Department of a tertiary hospital in Uganda, having sustained complex injuries due to an inadvertent AK-47 rifle gunshot injury. The gunshot injury was to the right side of her face with a large ragged entry wound and no exit wound. Prior basic wound care and radiological imaging showed a comminuted fracture of her mandible with lodgment of the bullet in her neck, anterior to her sixth and seventh cervical vertebrae. Standard debridement of her wound was done. A computed tomography scan showed an apparent cephalad shift ('wandering') of the bullet, leaving it lying partially anterior to her fifth cervical vertebra as well as within her carotid sheath. Other injuries were to her facial and trigeminal nerves, and her middle ear. The 'wandering' bullet was successfully removed surgically. It had caused no damage to any part of her neck structure. AK-47 rifle bullet injuries may present with uncharacteristically large entry wounds and cause complex structural injuries at the area of impact. The consequent trajectory is difficult to predict making regional examination and radiological investigations essential in management. Bullets may be retained, leaving no exit wound. Securing the airway, controlling hemorrhage and identifying other injuries are the first vital steps. This case illustrates all these interventions and the

  20. Test and Numerical Analysis for Penetration Residual Velocity of Bullet Considering Failure Strain Uncertainty of Composite Plates

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Myungseok; Lee, Minhyung [Sejong Univ., Sejong (Korea, Republic of)

    2016-03-15

    The ballistic performance data of composite materials is distributed due to material inhomogeneity. In this paper, the uncertainty in residual velocity is obtained experimentally, and a method of predicting it is established numerically for the high-speed impact of a bullet into laminated composites. First, the failure strain distribution was obtained by conducting a tensile test using 10 specimens. Next, a ballistic impact test was carried out for the impact of a fragment-simulating projectile (FSP) bullet with 4ply ([0/90]s) and 8ply ([0/90/0/90]s) glass fiber reinforced plastic (GFRP) plates. Eighteen shots were made at the same impact velocity and the residual velocities were obtained. Finally, simulations were conducted to predict the residual velocities by using the failure strain distributions that were obtained from the tensile test. For this simulation, two impact velocities were chosen at 411.7m/s (4ply) and 592.5m/s (8ply). The simulation results show that the predicted residual velocities are in close agreement with test results. Additionally, the modeling of a composite plate with layered solid elements requires less calculation time than modeling with solid elements.

  1. Detection of lead nanoparticles in game meat by single particle ICP-MS following use of lead-containing bullets.

    Science.gov (United States)

    Kollander, Barbro; Widemo, Fredrik; Ågren, Erik; Larsen, Erik H; Loeschner, Katrin

    2017-03-01

    This study investigated whether game meat may contain nanoparticles of lead from ammunition. Lead nanoparticles in the range 40 to 750 nm were detected by ICP-MS in single particle mode in game shot with lead-containing bullets. The median diameter of the detected nanoparticles was around 60 nm. The particle mass concentration ranged from 290 to 340 ng/g meat and the particle number concentrations from 27 to 50 million particles/g meat. The size limit of detection strongly depended on the level of dissolved lead and was in the range of 40 to 80 nm. In game meat sampled more than 10 cm away from the wound channel, no lead particles with a diameter larger than 40 nm were detected. In addition to dissolved lead in meat that originated from particulates, the presence of lead nano particles in game meat represents a hitherto unattended source of lead with a largely unknown toxicological impact to humans. Graphical Abstract Detection of lead nanoparticles in game meat by single particle ICP-MS following use of leadcontaining bullets.

  2. Self-action of Bessel wave packets in a system of coupled light guides and formation of light bullets

    Energy Technology Data Exchange (ETDEWEB)

    Balakin, A. A., E-mail: balakin.alexey@yandex.ru; Mironov, V. A.; Skobelev, S. A., E-mail: sk.sa1981@gmail.com [Russian Academy of Sciences, Institute of Applied Physics (Russian Federation)

    2017-01-15

    The self-action of two-dimensional and three-dimensional Bessel wave packets in a system of coupled light guides is considered using the discrete nonlinear Schrödinger equation. The features of the self-action of such wave fields are related to their initial strong spatial inhomogeneity. The numerical simulation shows that for the field amplitude exceeding a critical value, the development of an instability typical of a medium with the cubic nonlinearity is observed. Various regimes are studied: the self-channeling of a wave beam in one light guide at powers not strongly exceeding a critical value, the formation of the “kaleidoscopic” picture of a wave packet during the propagation of higher-power radiation along a stratified medium, the formation of light bullets during competition between self-focusing and modulation instabilities in the case of three-dimensional wave packets, etc. In the problem of laser pulse shortening, the situation is considered when the wave-field stratification in the transverse direction dominates. This process is accompanied by the self-compression of laser pulses in well enough separated light guides. The efficiency of conversion of the initial Bessel field distribution to two flying parallel light bullets is about 50%.

  3. Lead arthritis and lead poisoning following bullet wounds: a clinicopathologic, ultrastructural, and microanalytic study of two cases.

    Science.gov (United States)

    Slavin, R E; Swedo, J; Cartwright, J; Viegas, S; Custer, E M

    1988-02-01

    Bullet wounds causing lead synovitis in the wrist and knee are reported in two patients, one of whom also developed clinical plumbism. Very high lead levels in the synovial fluid are believed to be responsible for toxicity changes that occurred in the synovium and bone. Ultrastructurally, these alterations included the formation of nuclear lead inclusions, dilation, and degranulation of the rough endoplasmic reticulum and deposition of crystalline precipitates in the matrix of the mitochondria in macrophages, osteoclasts, and synoviocytes, as well as the development of cytoplasmic lead inclusions in osteoclasts. Energy-dispersive x-ray elemental analysis (EDXEA) indicated that the nuclear inclusions contained only lead, whereas precipitates within the mitochondria and elsewhere in the cytoplasm were composed of complexes containing lead, calcium, and phosphorus. Similarly constituted extracellular complexes were incorporated into newly formed trabecular bone laid down as a physiologic response to the bullet lodged within the wrist bones. This bone subsequently exhibited defects in bone resorption, which were characterized by depressed osteoclastic function and a unique lesion termed incomplete osteocytic osteolysis. The genesis of this latter lesion is uncertain. The sequestration of the partially degraded bone fragments containing lead complexes into the marrow and eventually into the joint spaces and synovium permitted the recycling of bone lead, and this may have played an important role in inducing clinical plumbism in one of the patients in this study.

  4. Combination of natural fiber Boehmeria nivea (ramie) with matrix epoxide for bullet proof vest body armor

    Energy Technology Data Exchange (ETDEWEB)

    Anggoro, Didi Dwi, E-mail: anggorophd@gmail.com; Kristiana, Nunung, E-mail: nuna.c631@gmail.com [Master of Chemical Engineering, Faculty of Engineering, Diponegoro University Jln. Prof. Sudharto, Tembalang, Semarang, 50239 (Indonesia)

    2015-12-29

    Ballistic protection equipment, such as a bulletproof vest, is a soldier’s most important means of preserving life and survivability in extreme combat conditions. The bulletproof vests are designed to protect the user’s chest from injury without disturbing the ability to perform his duties. Aromatic polyamide or aramid fibers known under the trade name Kevlar, Trawon and so is synthetic fiber materials commonly used in the manufacture of bulletproof vests. This synthetic fibers have high tensile strength and ductility. Kevlar is expensive and imported material. In this study, will introduce local natural raw materials, ramie fiber (Boehmeria nivea) which is cheaper and environmentally friendly. It has enough tenacity and tensile strength as a bulletproof vest. This experiment uses two panels, there are Panel A as front surface of Panel B. Panel A is a combination of ramie and epoxide matrix, while panel B is only ramie. From several variations of experimental combinations between Panel A and Panel B, optimal combination obtained with 16 layers of panel A and 31-34 layers of panel B which is able to protect againts cal. 7.65 mm × 17 mm (.32 ACP) bullet fired through pistol .32 Pindad from a distance of 20 meters. Panel with a size of 20 cm × 20 cm has a total thickness between 12,922 to13,745 mm and a total weight between 506,26 to 520,926gram. Scanning electron microscopy (SEM) observations indicated that the porosity and surface area of the ramie fiber is smooth, fiber surfaces showed topography with micropores. SEM also showed well-arranged structure of fibers bonding. Energy Dispersive X-ray (EDX) analysis indicated 100 % carbon contents in ramie fiber. Test result indicates that panel from composite ramie-epoxide can reach the level 1of International Standard of NIJ - 010104. Compared to panel from polyester fiber, the panel from composite ramie-epoxide (0,50-0,52 kg) is lighter weight than panel polyester fiber (1,642 kg)

  5. Spectroscopic Confirmation of a z = 6.740 Galaxy behind the Bullet Cluster

    Science.gov (United States)

    Bradač, Maruša; Vanzella, Eros; Hall, Nicholas; Treu, Tommaso; Fontana, Adriano; Gonzalez, Anthony H.; Clowe, Douglas; Zaritsky, Dennis; Stiavelli, Massimo; Clément, Benjamin

    2012-08-01

    We present the first results of our spectroscopic follow-up of 6.5 dropout behind the Bullet Cluster. We detect an emission line at λ = 9412 Å at >5σ significance using a 16 hr long exposure with FORS2 VLT. Based on the absence of flux in bluer broadband filters, the blue color of the source, and the absence of additional lines, we identify the line as Lyα at z = 6.740 ± 0.003. The integrated line flux is f = (0.7 ± 0.1 ± 0.3) × 10-17 erg-1 s-1 cm-2 (the uncertainties are due to random and flux calibration errors, respectively) making it the faintest Lyα flux detected at these redshifts. Given the magnification of μ = 3.0 ± 0.2 the intrinsic (corrected for lensing) flux is f int = (0.23 ± 0.03 ± 0.10 ± 0.02) × 10-17 erg-1 s-1 cm-2 (additional uncertainty due to magnification), which is ~2-3 times fainter than other such measurements in z ~ 7 galaxies. The intrinsic H 160W-band magnitude of the object is m^int_{H_160W}=27.57+/- 0.17, corresponding to 0.5 L* for LBGs at these redshifts. The galaxy is one of the two sub-L* LBG galaxies spectroscopically confirmed at these high redshifts (the other is also a lensed z = 7.045 galaxy), making it a valuable probe for the neutral hydrogen fraction in the early universe. Observations were carried out using the Very Large Telescope at the ESO Paranal Observatory under Program ID 088.A-0542. Also based on observations made with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555 and NNX08AD79G. These observations are associated with programs GO10200, GO10863, and GO11099.

  6. Combination of natural fiber Boehmeria nivea (ramie) with matrix epoxide for bullet proof vest body armor

    International Nuclear Information System (INIS)

    Anggoro, Didi Dwi; Kristiana, Nunung

    2015-01-01

    Ballistic protection equipment, such as a bulletproof vest, is a soldier’s most important means of preserving life and survivability in extreme combat conditions. The bulletproof vests are designed to protect the user’s chest from injury without disturbing the ability to perform his duties. Aromatic polyamide or aramid fibers known under the trade name Kevlar, Trawon and so is synthetic fiber materials commonly used in the manufacture of bulletproof vests. This synthetic fibers have high tensile strength and ductility. Kevlar is expensive and imported material. In this study, will introduce local natural raw materials, ramie fiber (Boehmeria nivea) which is cheaper and environmentally friendly. It has enough tenacity and tensile strength as a bulletproof vest. This experiment uses two panels, there are Panel A as front surface of Panel B. Panel A is a combination of ramie and epoxide matrix, while panel B is only ramie. From several variations of experimental combinations between Panel A and Panel B, optimal combination obtained with 16 layers of panel A and 31-34 layers of panel B which is able to protect againts cal. 7.65 mm × 17 mm (.32 ACP) bullet fired through pistol .32 Pindad from a distance of 20 meters. Panel with a size of 20 cm × 20 cm has a total thickness between 12,922 to13,745 mm and a total weight between 506,26 to 520,926gram. Scanning electron microscopy (SEM) observations indicated that the porosity and surface area of the ramie fiber is smooth, fiber surfaces showed topography with micropores. SEM also showed well-arranged structure of fibers bonding. Energy Dispersive X-ray (EDX) analysis indicated 100 % carbon contents in ramie fiber. Test result indicates that panel from composite ramie-epoxide can reach the level 1of International Standard of NIJ - 010104. Compared to panel from polyester fiber, the panel from composite ramie-epoxide (0,50-0,52 kg) is lighter weight than panel polyester fiber (1,642 kg)

  7. Alternatives to currently used antimalarial drugs: in search of a magic bullet.

    Science.gov (United States)

    Bhagavathula, Akshaya Srikanth; Elnour, Asim Ahmed; Shehab, Abdulla

    2016-11-04

    bullet against malaria. Future studies should focus on effective single-dose molecules that can act against all stages of malaria in order to prevent transmission. Newer medicines have also raised concerns in terms of efficacy and safety. Overall, more evidence is needed to effectively reduce the current malaria burden. Treatment strategies that target the blood stage with transmission-blocking properties are needed to prevent future drug resistance.

  8. Classification in context

    DEFF Research Database (Denmark)

    Mai, Jens Erik

    2004-01-01

    This paper surveys classification research literature, discusses various classification theories, and shows that the focus has traditionally been on establishing a scientific foundation for classification research. This paper argues that a shift has taken place, and suggests that contemporary...... classification research focus on contextual information as the guide for the design and construction of classification schemes....

  9. Classification of the web

    DEFF Research Database (Denmark)

    Mai, Jens Erik

    2004-01-01

    This paper discusses the challenges faced by investigations into the classification of the Web and outlines inquiries that are needed to use principles for bibliographic classification to construct classifications of the Web. This paper suggests that the classification of the Web meets challenges...... that call for inquiries into the theoretical foundation of bibliographic classification theory....

  10. Hazard classification methodology

    International Nuclear Information System (INIS)

    Brereton, S.J.

    1996-01-01

    This document outlines the hazard classification methodology used to determine the hazard classification of the NIF LTAB, OAB, and the support facilities on the basis of radionuclides and chemicals. The hazard classification determines the safety analysis requirements for a facility

  11. Biographical Sources in the Sciences--Life, Earth and Physical Sciences (1989-2006). LC Science Tracer Bullet. TB 06-4

    Science.gov (United States)

    Freitag, Ruth, Comp.; Bradley, Michelle Cadoree, Comp.

    2006-01-01

    This guide offers a systematic approach to the wide variety of published biographical information on men and women of science in the life, earth and physical sciences, primarily from 1989 to 2006, and complements Library of Congress Science Tracer Bullet "TB88-3" ("Biographical Sources in the Sciences," compiled 1988 [ED306074]) and "TB06-7"…

  12. Collective Classification in Network Data

    OpenAIRE

    Sen, Prithviraj; Namata, Galileo; Bilgic, Mustafa; Getoor, Lise; University of Maryland; Galligher, Brian; Eliassi-Rad, Tina

    2008-01-01

    Many real-world applications produce networked data such as the world-wide web (hypertext documents connected via hyperlinks), social networks (for example, people connected by friendship links), communication networks (computers connected via communication links) and biological networks (for example, protein interaction networks). A recent focus in machine learning research has been to extend traditional machine learning classification techniques to classify nodes in such networks. In this a...

  13. Marine biology

    International Nuclear Information System (INIS)

    Thurman, H.V.; Webber, H.H.

    1984-01-01

    This book discusses both taxonomic and ecological topics on marine biology. Full coverage of marine organisms of all five kingdoms is provided, along with interesting and thorough discussion of all major marine habitats. Organization into six major parts allows flexibility. It also provides insight into important topics such as disposal of nuclear waste at sea, the idea that life began on the ocean floor, and how whales, krill, and people interact. A full-color photo chapter reviews questions, and exercises. The contents are: an overview marine biology: fundamental concepts/investigating life in the ocean; the physical ocean, the ocean floor, the nature of water, the nature and motion of ocean water; general ecology, conditions for life in the sea, biological productivity and energy transfer; marine organisms; monera, protista, mycota and metaphyta; the smaller marine animals, the large animals marine habitats, the intertidal zone/benthos of the continental shelf, the photic zone, the deep ocean, the ocean under stress, marine pollution, appendix a: the metric system and conversion factors/ appendix b: prefixes and suffixes/ appendix c: taxonomic classification of common marine organisms, and glossary, and index

  14. Focusing Cosmic Telescopes: Exploring Redshift z ~ 5-6 Galaxies with the Bullet Cluster 1E0657 - 56

    Science.gov (United States)

    Bradač, Maruša; Treu, Tommaso; Applegate, Douglas; Gonzalez, Anthony H.; Clowe, Douglas; Forman, William; Jones, Christine; Marshall, Phil; Schneider, Peter; Zaritsky, Dennis

    2009-12-01

    The gravitational potential of clusters of galaxies acts as a cosmic telescope allowing us to find and study galaxies at fainter limits than otherwise possible and thus probe closer to the epoch of formation of the first galaxies. We use the Bullet cluster 1E0657 - 56 (z = 0.296) as a case study, because its high mass and merging configuration makes it one of the most efficient cosmic telescopes we know. We develop a new algorithm to reconstruct the gravitational potential of the Bullet cluster based on a non-uniform adaptive grid, combining strong and weak gravitational lensing data derived from deep Hubble Space Telescope/Advanced Camera for Surveys F606W-F775W-F850LP and ground-based imaging. We exploit this improved mass map to study z ~ 5-6 Lyman break galaxies (LBGs), which we detect as dropouts. One of the LBGs is multiply imaged, providing a geometric confirmation of its high redshift, and is used to further improve our mass model. We quantify the uncertainties in the magnification map reconstruction in the intrinsic source luminosity, and in the volume surveyed, and show that they are negligible compared to sample variance when determining the luminosity function of high-redshift galaxies. With shallower and comparable magnitude limits to Hubble Ultra Deep Field (HUDF) and Great Observatories Origins Deep Survey (GOODS), the Bullet cluster observations, after correcting for magnification, probe deeper into the luminosity function of the high-redshift galaxies than GOODS and only slightly shallower than HUDF. We conclude that accurately focused cosmic telescopes are the most efficient way to sample the bright end of the luminosity function of high-redshift galaxies and—in case they are multiply imaged—confirm their redshifts. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5

  15. Implications for wildlife and humans of dietary exposure to lead from fragments of lead rifle bullets in deer shot in the UK

    International Nuclear Information System (INIS)

    Knott, Jeff; Gilbert, Jo; Hoccom, David G.; Green, Rhys E.

    2010-01-01

    Lead poisoning caused by ingested spent lead shotgun pellets has long been known to be a cause of unnecessary mortality in waterfowl and has led to legislation limiting its use in many countries. Recent evidence has shown that the problem extends to terrestrial ecosystems and to fragmented rifle bullets eaten by scavengers as well as shotgun pellets. Dietary exposure of human consumers to lead from spent ammunition in game meat also poses potential risks to human health. To assess the degree of fragmentation of lead bullets used to kill wild deer, twelve deer were shot in the thorax using copper-jacketed lead-cored bullets, as part of planned deer management operations. The thoracic region of the eviscerated carcasses and the abdominal viscera of each deer were X-rayed. An average of 356 metal fragments was visible on radiographs of the carcass and 180 fragments in the viscera. The weight of fragments was estimated by reference to an X-rayed scale of fragments of known weight. The average total weight of metal fragments, likely to be mostly lead, was estimated to be 1.2 g for the carcass and 0.2 g for the viscera. The total estimated weight of fragments in the entire carcass was estimated to be 17% of the weight of the bullet. Most fragments were small in size, with those in the viscera being smaller than those in the carcass. Metal fragments in the viscera were sufficiently small that at least 80% of the metallic bullet-derived lead in the viscera would be expected to be ingested by scavenging birds, such as buzzards and eagles, which feed on them.

  16. Implications for wildlife and humans of dietary exposure to lead from fragments of lead rifle bullets in deer shot in the UK

    Energy Technology Data Exchange (ETDEWEB)

    Knott, Jeff, E-mail: jeff.knott@rspb.org.uk [Royal Society for the Protection of Birds, The Lodge, Sandy, Bedfordshire SG19 2DL (United Kingdom); Gilbert, Jo; Hoccom, David G. [Royal Society for the Protection of Birds, The Lodge, Sandy, Bedfordshire SG19 2DL (United Kingdom); Green, Rhys E. [Royal Society for the Protection of Birds, The Lodge, Sandy, Bedfordshire SG19 2DL (United Kingdom); Conservation Science Group, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ (United Kingdom)

    2010-12-01

    Lead poisoning caused by ingested spent lead shotgun pellets has long been known to be a cause of unnecessary mortality in waterfowl and has led to legislation limiting its use in many countries. Recent evidence has shown that the problem extends to terrestrial ecosystems and to fragmented rifle bullets eaten by scavengers as well as shotgun pellets. Dietary exposure of human consumers to lead from spent ammunition in game meat also poses potential risks to human health. To assess the degree of fragmentation of lead bullets used to kill wild deer, twelve deer were shot in the thorax using copper-jacketed lead-cored bullets, as part of planned deer management operations. The thoracic region of the eviscerated carcasses and the abdominal viscera of each deer were X-rayed. An average of 356 metal fragments was visible on radiographs of the carcass and 180 fragments in the viscera. The weight of fragments was estimated by reference to an X-rayed scale of fragments of known weight. The average total weight of metal fragments, likely to be mostly lead, was estimated to be 1.2 g for the carcass and 0.2 g for the viscera. The total estimated weight of fragments in the entire carcass was estimated to be 17% of the weight of the bullet. Most fragments were small in size, with those in the viscera being smaller than those in the carcass. Metal fragments in the viscera were sufficiently small that at least 80% of the metallic bullet-derived lead in the viscera would be expected to be ingested by scavenging birds, such as buzzards and eagles, which feed on them.

  17. Detection of lead nanoparticles in game meat by single particle ICP-MS following use of lead-containing bullets

    DEFF Research Database (Denmark)

    Kollander, Barbro; Widemo, Fredrik; Ågren, Erik

    2017-01-01

    This study investigated whether game meat may contain nanoparticles of lead from ammunition. Lead nanoparticles in the range 40 to 750 nm were detected by ICP-MS in single particle mode in game shot with lead-containing bullets. The median diameter of the detected nanoparticles was around 60 nm....... The particle mass concentration ranged from 290 to 340 ng/g meat and the particle number concentrations from 27 to 50 million particles/g meat. The size limit of detection strongly depended on the level of dissolved lead and was in the range of 40 to 80 nm. In game meat sampled more than 10 cm away from...... the wound channel, no lead particles with a diameter larger than 40 nm were detected. In addition to dissolved lead in meat that originated from particulates, the presence of lead nano particles in game meat represents a hitherto unattended source of lead with a largely unknown toxicological impact...

  18. Classifying Life, Reconstructing History and Teaching Diversity: Philosophical Issues in the Teaching of Biological Systematics and Biodiversity

    Science.gov (United States)

    Reydon, Thomas A. C.

    2013-01-01

    Classification is a central endeavor in every scientific field of work. Classification in biology, however, is distinct from classification in other fields of science in a number of ways. Thus, understanding how biological classification works is an important element in understanding the nature of biological science. In the present paper, I…

  19. Whewell on classification and consilience.

    Science.gov (United States)

    Quinn, Aleta

    2017-08-01

    In this paper I sketch William Whewell's attempts to impose order on classificatory mineralogy, which was in Whewell's day (1794-1866) a confused science of uncertain prospects. Whewell argued that progress was impeded by the crude reductionist assumption that all macroproperties of crystals could be straightforwardly explained by reference to the crystals' chemical constituents. By comparison with biological classification, Whewell proposed methodological reforms that he claimed would lead to a natural classification of minerals, which in turn would support advances in causal understanding of the properties of minerals. Whewell's comparison to successful biological classification is particularly striking given that classificatory biologists did not share an understanding of the causal structure underlying the natural classification of life (the common descent with modification of all organisms). Whewell's key proposed methodological reform is consideration of multiple, distinct principles of classification. The most powerful evidence in support of a natural classificatory claim is the consilience of claims arrived at through distinct lines of reasoning, rooted in distinct conceptual approaches to the target objects. Mineralogists must consider not only elemental composition and chemical affinities, but also symmetry and polarity. Geometrical properties are central to what makes an individual mineral the type of mineral that it is. In Whewell's view, function and organization jointly define life, and so are the keys to understanding what makes an organism the type of organism that it is. I explain the relationship between Whewell's teleological account of life and his natural theology. I conclude with brief comments about the importance of Whewell's classificatory theory for the further development of his philosophy of science and in particular his account of consilience. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. SAW Classification Algorithm for Chinese Text Classification

    OpenAIRE

    Xiaoli Guo; Huiyu Sun; Tiehua Zhou; Ling Wang; Zhaoyang Qu; Jiannan Zang

    2015-01-01

    Considering the explosive growth of data, the increased amount of text data’s effect on the performance of text categorization forward the need for higher requirements, such that the existing classification method cannot be satisfied. Based on the study of existing text classification technology and semantics, this paper puts forward a kind of Chinese text classification oriented SAW (Structural Auxiliary Word) algorithm. The algorithm uses the special space effect of Chinese text where words...

  1. Computational aspects of systematic biology.

    Science.gov (United States)

    Lilburn, Timothy G; Harrison, Scott H; Cole, James R; Garrity, George M

    2006-06-01

    We review the resources available to systematic biologists who wish to use computers to build classifications. Algorithm development is in an early stage, and only a few examples of integrated applications for systematic biology are available. The availability of data is crucial if systematic biology is to enter the computer age.

  2. Investigation about the influence of the mechanical properties of lead core and brass jacket of a NATO 7.62 mm ball bullet in numerical simulations of ballistic impacts

    Directory of Open Access Journals (Sweden)

    Scapin M.

    2012-08-01

    Full Text Available In the present work a validated numerical approach has been used in order to build a robust and reliable FE model of the impact of a NATO 7.62 mm ball bullet, against an aluminium transmission shaft. The bullet is a full metal jacket type, with a lead alloy core and a brass jacket. Target shaft is made by an Al6061-T6 aluminium alloy. According to the soft core (lead alloy of the bullet, most effort has been spent in order to evaluate the effect of bullet materials mechanical properties on the numerical results. Numerical analyses, carried out using the non-linear dynamic finite element solver Abaqus∖Explicit 6.10, have been performed focusing on core and jacket material behaviour (target material, Al6061-T6, has been previously calibrated by the authors. Thus numerical analyses have been performed considering for the mechanical behaviour of the bullet both a simplified approach (as reported in literature and new material data (with strain rate effect obtained by means of experimental tests on the two materials (lead and brass with specimens cut directly from the bullet. Finally the results of the analyses have been compared with real experimental ballistic tests.

  3. Asteroid taxonomic classifications

    International Nuclear Information System (INIS)

    Tholen, D.J.

    1989-01-01

    This paper reports on three taxonomic classification schemes developed and applied to the body of available color and albedo data. Asteroid taxonomic classifications according to two of these schemes are reproduced

  4. Muzzle-loading weapons discharging spherical lead bullets: two case studies and experimental simulation using a skin-soap composite model.

    Science.gov (United States)

    Große Perdekamp, Markus; Braunwarth, Roland; Kromeier, Jan; Nadjem, Hadi; Pollak, Stefan; Thierauf, Annette

    2013-07-01

    In current forensic practice, fatal injuries from black powder guns are rare events. In contact and close-range shots, the intensity of GSR deposition (soot, powder particles) is much greater than that in shots with smokeless powder ammunition. The same applies to any burning effects from the combustion gases. Besides, a wad of felt interposed between the propellant and the lead bullet may enter the wound channel. Apart from these findings seen in close-range shots, another characteristic feature results from the mostly spherical shape of the missiles causing maximum tissue damage at the entrance site. Two fatal injuries inflicted with muzzle-loading weapons are reported. In the first case, suicide was committed with a cal. 11.6 mm miniature cannon by firing a contact shot to the back of the neck. In test shots using black powder (1 and 2 g) as propellant, the mean bullet velocity measured 1 m away from the weapon was 87.11 and 146.85 m/s, respectively, corresponding to a kinetic energy of 32.49 and 92.95 J, respectively. Contact test shots to composite models consisting of ballistic soap covered by pig skin at the entrance site were evaluated by CT and revealed cone-like cavitations along the bullet path as known from spherical missiles and penetration depths up to 25 cm. The second case presented deals with a homicidal close-range shot discharged from a muzzle-loading percussion pistol cal. .44. The skin around the entrance site (root of the nose) was densely covered with blackish soot and powder particles, whereas the eyebrows and eyelashes showed singeing of the hairs. The flattened bullet and the wad had got stuck under the scalp of the occipital region. In both cases, there was a disproportionally large zone of tissue destruction in the initial parts of the wound tracks.

  5. Hybrid treatment of bullet embolism at the abdominal aortic bifurcation, complicated with thoracoabdominal aorta pseudoaneurysm and common iliac artery occlusion: case report

    Directory of Open Access Journals (Sweden)

    Patrick Bastos Metzger

    2014-03-01

    Full Text Available Embolization due to a firearm projectile entering the bloodstream is a rare event that is unlikely to be suspected during initial treatment of trauma patients. We describe and discuss a case of bullet embolism of the abdominal aortic bifurcation, complicated by a pseudoaneurysm of the thoracoabdominal aorta and occlusion of the right common iliac artery, but successfully treated using a combination of endovascular methods and conventional surgery.

  6. Hand eczema classification

    DEFF Research Database (Denmark)

    Diepgen, T L; Andersen, Klaus Ejner; Brandao, F M

    2008-01-01

    of the disease is rarely evidence based, and a classification system for different subdiagnoses of hand eczema is not agreed upon. Randomized controlled trials investigating the treatment of hand eczema are called for. For this, as well as for clinical purposes, a generally accepted classification system...... A classification system for hand eczema is proposed. Conclusions It is suggested that this classification be used in clinical work and in clinical trials....

  7. Classification with support hyperplanes

    NARCIS (Netherlands)

    G.I. Nalbantov (Georgi); J.C. Bioch (Cor); P.J.F. Groenen (Patrick)

    2006-01-01

    textabstractA new classification method is proposed, called Support Hy- perplanes (SHs). To solve the binary classification task, SHs consider the set of all hyperplanes that do not make classification mistakes, referred to as semi-consistent hyperplanes. A test object is classified using

  8. Standard classification: Physics

    International Nuclear Information System (INIS)

    1977-01-01

    This is a draft standard classification of physics. The conception is based on the physics part of the systematic catalogue of the Bayerische Staatsbibliothek and on the classification given in standard textbooks. The ICSU-AB classification now used worldwide by physics information services was not taken into account. (BJ) [de

  9. Classification of refrigerants; Classification des fluides frigorigenes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This document was made from the US standard ANSI/ASHRAE 34 published in 2001 and entitled 'designation and safety classification of refrigerants'. This classification allows to clearly organize in an international way the overall refrigerants used in the world thanks to a codification of the refrigerants in correspondence with their chemical composition. This note explains this codification: prefix, suffixes (hydrocarbons and derived fluids, azeotropic and non-azeotropic mixtures, various organic compounds, non-organic compounds), safety classification (toxicity, flammability, case of mixtures). (J.S.)

  10. The Classification of Living Things: Nature in the Classroom.

    Science.gov (United States)

    Doyle, Charles

    1982-01-01

    Use of a classification system in teaching biology is presented as a concept aiding students' understanding of the diversity of plants and animals. The principles of classification are summarized and six learning strategies are given to show relationships among groups. (CM)

  11. Towards a biologically meaningful classification of subterranean organisms: a critical analysis of the Schiner-Racovitza system from a historical perspective, difficulties of its application and implications for conservation

    Directory of Open Access Journals (Sweden)

    Eleonora Trajano

    2017-02-01

    Full Text Available Subterranean organisms always attracted the attention of humans using caves with various purposes, due to the strange appearance of several among them and life in an environment considered extreme. According to a classification based on the evolutionary and ecological relationships of these organisms with subterranean habitats, first proposed by Schiner in 1854 and emended by Racovitza in 1907, three categories have been recognized: troglobites, troglophles and trogloxenes. The Schiner-Racovitza system has been discussed, criticized, emended, the categories have been redefined, subdivided, original meanings have changed, but it is used until now. Herein we analyze in a conceptual framework the main ecological classifications of subterranean organisms, from Schiner to Trajano, in 2012, so far the last author to introduce a relevant conceptual change on the categories definitions, incorporating the source-sink population model. Conceptual inconsistencies are pointed, especially with regards to the generally ill-defined trogloxene category, and the correspondence between categories according to the original sense and in alternative classifications is discussed. Practical criteria for distinction between these categories and difficulties for their application are presented. The importance of rightly classifying subterranean populations according to the Schiner-Racovitza system for conservation of these fragile and mostly threatened habitats is discussed.

  12. Classification, disease, and diagnosis.

    Science.gov (United States)

    Jutel, Annemarie

    2011-01-01

    Classification shapes medicine and guides its practice. Understanding classification must be part of the quest to better understand the social context and implications of diagnosis. Classifications are part of the human work that provides a foundation for the recognition and study of illness: deciding how the vast expanse of nature can be partitioned into meaningful chunks, stabilizing and structuring what is otherwise disordered. This article explores the aims of classification, their embodiment in medical diagnosis, and the historical traditions of medical classification. It provides a brief overview of the aims and principles of classification and their relevance to contemporary medicine. It also demonstrates how classifications operate as social framing devices that enable and disable communication, assert and refute authority, and are important items for sociological study.

  13. Influence Factors Regarding the Effectiveness of Automated Ballistic Comparison on 0.38 Special Caliber Bullets and Cartridge Cases.

    Science.gov (United States)

    Dos Santos, Lehi Sudy; Vieira Muterlle, Palloma

    2018-03-01

    Factors influencing effectiveness of automated comparisons, test-fired bullets, and cartridge cases from 0.38 Special revolvers were logged into the Evofinder ® Ballistic ID System. Tests were performed as follows: First test correlated test-fires of the same type, second test compared different types of ammunition components, third test replicated the second test in a larger database, and fourth test replicated the third test with students having no previous firearm identification experience. System effectiveness with projectiles in the first test was 0.89. With cartridge cases, effectiveness was 0.79 with combined results, but analysis of separate results by breech face and firing pin revealed low effectiveness by breech face (0.40). In the second, third, and fourth tests, effectiveness with projectiles were 0.61, 0.51, and 0.44. In addition, these tests had effectiveness with cartridge cases equivalent to 0.55, 0.43, and 0.44. Results are useful to establish routine protocols, system improvements, or comparative assessment of other electronic systems. © 2018 American Academy of Forensic Sciences.

  14. Environment and air pollution like gun and bullet for low-income countries: war for better health and wealth.

    Science.gov (United States)

    Zou, Xiang; Azam, Muhammad; Islam, Talat; Zaman, Khalid

    2016-02-01

    The objective of the study is to examine the impact of environmental indicators and air pollution on "health" and "wealth" for the low-income countries. The study used a number of promising variables including arable land, fossil fuel energy consumption, population density, and carbon dioxide emissions that simultaneously affect the health (i.e., health expenditures per capita) and wealth (i.e., GDP per capita) of the low-income countries. The general representation for low-income countries has shown by aggregate data that consist of 39 observations from the period of 1975-2013. The study decomposes the data set from different econometric tests for managing robust inferences. The study uses temporal forecasting for the health and wealth model by a vector error correction model (VECM) and an innovation accounting technique. The results show that environment and air pollution is the menace for low-income countries' health and wealth. Among environmental indicators, arable land has the largest variance to affect health and wealth for the next 10-year period, while air pollution exerts the least contribution to change health and wealth of low-income countries. These results indicate the prevalence of war situation, where environment and air pollution become visible like "gun" and "bullet" for low-income countries. There are required sound and effective macroeconomic policies to combat with the environmental evils that affect the health and wealth of the low-income countries.

  15. Security classification of information

    Energy Technology Data Exchange (ETDEWEB)

    Quist, A.S.

    1993-04-01

    This document is the second of a planned four-volume work that comprehensively discusses the security classification of information. The main focus of Volume 2 is on the principles for classification of information. Included herein are descriptions of the two major types of information that governments classify for national security reasons (subjective and objective information), guidance to use when determining whether information under consideration for classification is controlled by the government (a necessary requirement for classification to be effective), information disclosure risks and benefits (the benefits and costs of classification), standards to use when balancing information disclosure risks and benefits, guidance for assigning classification levels (Top Secret, Secret, or Confidential) to classified information, guidance for determining how long information should be classified (classification duration), classification of associations of information, classification of compilations of information, and principles for declassifying and downgrading information. Rules or principles of certain areas of our legal system (e.g., trade secret law) are sometimes mentioned to .provide added support to some of those classification principles.

  16. Classification of Flotation Frothers

    Directory of Open Access Journals (Sweden)

    Jan Drzymala

    2018-02-01

    Full Text Available In this paper, a scheme of flotation frothers classification is presented. The scheme first indicates the physical system in which a frother is present and four of them i.e., pure state, aqueous solution, aqueous solution/gas system and aqueous solution/gas/solid system are distinguished. As a result, there are numerous classifications of flotation frothers. The classifications can be organized into a scheme described in detail in this paper. The frother can be present in one of four physical systems, that is pure state, aqueous solution, aqueous solution/gas and aqueous solution/gas/solid system. It results from the paper that a meaningful classification of frothers relies on choosing the physical system and next feature, trend, parameter or parameters according to which the classification is performed. The proposed classification can play a useful role in characterizing and evaluation of flotation frothers.

  17. Ontologies vs. Classification Systems

    DEFF Research Database (Denmark)

    Madsen, Bodil Nistrup; Erdman Thomsen, Hanne

    2009-01-01

    What is an ontology compared to a classification system? Is a taxonomy a kind of classification system or a kind of ontology? These are questions that we meet when working with people from industry and public authorities, who need methods and tools for concept clarification, for developing meta...... data sets or for obtaining advanced search facilities. In this paper we will present an attempt at answering these questions. We will give a presentation of various types of ontologies and briefly introduce terminological ontologies. Furthermore we will argue that classification systems, e.g. product...... classification systems and meta data taxonomies, should be based on ontologies....

  18. Sunyaev-Zel'Dovich effect observations of the bullet cluster (1E 0657-56) with APEX-SZ

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, N.W.; Lanting, T.; Ade, P.A.R.; Basu, K.; Bender, A.N.; Benson, B.A.; Bertoldi, F.; Cho, H.-M.; Chon, G.; Clarke, J.; Dobbs, M.; Ferrusca, D.; Gusten, R.; Holzapfel, W.L.; Kovacs, A.; Kennedy, J.; Kermish, Z.; Kneissl, R.; Lee, A.T.; Lueker, M.; Mehl, J.; Menten, K.M.; Muders, D.; Nord, M.; Pacaud, F.; Plagge, T.; Reichardt, C.; Richards, P.L.; Schaaf, R.; Schilke, P.; Schuller, F.; Schwan, D.; Spieler, H.; Tucker, C.; Weiss, A.; Zahn, O.

    2008-07-25

    We present observations of the Sunyaev-Zel'dovich effect (SZE) in the Bullet cluster (1E 0657-56) using the APEX-SZ instrument at 150 GHz with a resolution of 1'. The main results are maps of the SZE in this massive, merging galaxy cluster. The cluster is detected with 23 sigma significance within the central 1' radius of the source position. The SZE map has a broadly similar morphology to that in existing X-ray maps of this system, and we find no evidence for significant contamination of the SZE emission by radio or IR sources. In order to make simple quantitative comparisons with cluster gas models derived from X-ray observations, we fit our data to an isothermal elliptical beta model, despite the inadequacy of such a model for this complex merging system. With an X-ray derived prior on the power-law index, beta = 1.04+0.16-0.10, we find a core radius rc = 142" +- 18", an axial ratio of 0.889 +- 0.072, and a central temperature decrement of -771 +- 71 muKCMB, including a +-5.5percent flux calibration uncertainty. Combining the APEX-SZ map with a map of projected electron surface density from Chandra X-ray observations, we determine the mass-weighted temperature of the cluster gas to be Tmg = 10.8 +- 0.9 keV, significantly lower than some previously reported X-ray spectroscopic temperatures. Under the assumption of an isothermal cluster gas distribution in hydrostatic equilibrium, we compute the gas mass fraction for prolate and oblate spheroidal geometries and find it to be consistent with previous results from X-ray and weak-lensing observations. This work is the first result from the APEX-SZ experiment and represents the first reported scientific result from observations with a large array of multiplexed superconducting transition-edge sensor bolometers.

  19. A comparison of surface topography characterization technologies for use in comparing spent bullet and cartridge case signatures

    Energy Technology Data Exchange (ETDEWEB)

    Batishko, C.R.; Hickman, B.J.; Cuta, F.M.

    1992-11-01

    The Pacific Northwest Laboratory was tasked by the US Department of Energy to provide technical assistance to the Federal Bureau of Investigation in evaluating and ranking technologies potentially useful in high-speed comparison of unique spent bullet and cartridge case surface signatures. Information sources included vendor input, current relevant literature, vendor phone contacts, other FBI resources, relevant PNL reports, and personal contact with numerous PNL technical staff. A comprehensive list of technologies was reduced to a list of 38 by grouping very similar methodologies, and further reduced to a short list of six by applying a set of five minimum functional requirements. A total of 14 primary criteria, many having secondary criteria, were subsequently used to evaluate each technology. The ranked short list results are reported and supported in this document, and their scores normalized to a hypothetical ideal system are as follows: (1) confocal microscopy 82.13; (2) laser dynamic focusing 72.04; (3)moire interferometry V70.94; (4)fringe field capacitance;(5)laser triangulation 66.18; (6)structured/sectioned light 65.55. Information available within the time/budget constraints which was used for the evaluation and ranking was not sufficiently detailed to evaluate specific implementations of the technologies. Each of the technologies in the short list was judged potentially capable of meeting the minimum requirements. Clever, novel engineering solutions resulting in a more cost-effective system, or a closer fit to the ``ideal system,`` could result in a reordering of the short list when actual technical proposals are evaluated. Therefore, it is recommended that a Request for Proposal not be limited to only the highest ranked technology, but include all six technologies in the short list.

  20. A comparison of surface topography characterization technologies for use in comparing spent bullet and cartridge case signatures

    Energy Technology Data Exchange (ETDEWEB)

    Batishko, C.R.; Hickman, B.J.; Cuta, F.M.

    1992-11-01

    The Pacific Northwest Laboratory was tasked by the US Department of Energy to provide technical assistance to the Federal Bureau of Investigation in evaluating and ranking technologies potentially useful in high-speed comparison of unique spent bullet and cartridge case surface signatures. Information sources included vendor input, current relevant literature, vendor phone contacts, other FBI resources, relevant PNL reports, and personal contact with numerous PNL technical staff. A comprehensive list of technologies was reduced to a list of 38 by grouping very similar methodologies, and further reduced to a short list of six by applying a set of five minimum functional requirements. A total of 14 primary criteria, many having secondary criteria, were subsequently used to evaluate each technology. The ranked short list results are reported and supported in this document, and their scores normalized to a hypothetical ideal system are as follows: (1) confocal microscopy 82.13; (2) laser dynamic focusing 72.04; (3)moire interferometry V70.94; (4)fringe field capacitance;(5)laser triangulation 66.18; (6)structured/sectioned light 65.55. Information available within the time/budget constraints which was used for the evaluation and ranking was not sufficiently detailed to evaluate specific implementations of the technologies. Each of the technologies in the short list was judged potentially capable of meeting the minimum requirements. Clever, novel engineering solutions resulting in a more cost-effective system, or a closer fit to the ideal system,'' could result in a reordering of the short list when actual technical proposals are evaluated. Therefore, it is recommended that a Request for Proposal not be limited to only the highest ranked technology, but include all six technologies in the short list.

  1. Phenotype classification of zebrafish embryos by supervised learning.

    Directory of Open Access Journals (Sweden)

    Nathalie Jeanray

    Full Text Available Zebrafish is increasingly used to assess biological properties of chemical substances and thus is becoming a specific tool for toxicological and pharmacological studies. The effects of chemical substances on embryo survival and development are generally evaluated manually through microscopic observation by an expert and documented by several typical photographs. Here, we present a methodology to automatically classify brightfield images of wildtype zebrafish embryos according to their defects by using an image analysis approach based on supervised machine learning. We show that, compared to manual classification, automatic classification results in 90 to 100% agreement with consensus voting of biological experts in nine out of eleven considered defects in 3 days old zebrafish larvae. Automation of the analysis and classification of zebrafish embryo pictures reduces the workload and time required for the biological expert and increases the reproducibility and objectivity of this classification.

  2. Classification of radiological procedures

    International Nuclear Information System (INIS)

    1989-01-01

    A classification for departments in Danish hospitals which use radiological procedures. The classification codes consist of 4 digits, where the first 2 are the codes for the main groups. The first digit represents the procedure's topographical object and the second the techniques. The last 2 digits describe individual procedures. (CLS)

  3. Colombia: Territorial classification

    International Nuclear Information System (INIS)

    Mendoza Morales, Alberto

    1998-01-01

    The article is about the approaches of territorial classification, thematic axes, handling principles and territorial occupation, politician and administrative units and administration regions among other topics. Understanding as Territorial Classification the space distribution on the territory of the country, of the geographical configurations, the human communities, the political-administrative units and the uses of the soil, urban and rural, existent and proposed

  4. Munitions Classification Library

    Science.gov (United States)

    2016-04-04

    members of the community to make their own additions to any, or all, of the classification libraries . The next phase entailed data collection over less......Include area code) 04/04/2016 Final Report August 2014 - August 2015 MUNITIONS CLASSIFICATION LIBRARY Mr. Craig Murray, Parsons Dr. Thomas H. Bell, Leidos

  5. Recursive automatic classification algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Bauman, E V; Dorofeyuk, A A

    1982-03-01

    A variational statement of the automatic classification problem is given. The dependence of the form of the optimal partition surface on the form of the classification objective functional is investigated. A recursive algorithm is proposed for maximising a functional of reasonably general form. The convergence problem is analysed in connection with the proposed algorithm. 8 references.

  6. Library Classification 2020

    Science.gov (United States)

    Harris, Christopher

    2013-01-01

    In this article the author explores how a new library classification system might be designed using some aspects of the Dewey Decimal Classification (DDC) and ideas from other systems to create something that works for school libraries in the year 2020. By examining what works well with the Dewey Decimal System, what features should be carried…

  7. Spectroscopic classification of transients

    DEFF Research Database (Denmark)

    Stritzinger, M. D.; Fraser, M.; Hummelmose, N. N.

    2017-01-01

    We report the spectroscopic classification of several transients based on observations taken with the Nordic Optical Telescope (NOT) equipped with ALFOSC, over the nights 23-25 August 2017.......We report the spectroscopic classification of several transients based on observations taken with the Nordic Optical Telescope (NOT) equipped with ALFOSC, over the nights 23-25 August 2017....

  8. Atypical gunshot injury to the right side of the face with the bullet lodged in the carotid sheath: a case report

    OpenAIRE

    Ongom, Peter A; Kijjambu, Stephen C; Jombwe, Josephat

    2014-01-01

    Introduction Gunshot injuries of the head and neck from the AK-47 rifle (a common assault rifle, submachine gun type) are a significant contributor to morbidity and mortality among civilians in Sub-Saharan Africa. They may cause significant damage to the closely arranged structures in this region, and the bullet’s trajectory can be very difficult to determine. We present an unusual case of gunshot injury with an atypical bullet entry wound, profound injury to the face, lodgment in the right c...

  9. DOE LLW classification rationale

    International Nuclear Information System (INIS)

    Flores, A.Y.

    1991-01-01

    This report was about the rationale which the US Department of Energy had with low-level radioactive waste (LLW) classification. It is based on the Nuclear Regulatory Commission's classification system. DOE site operators met to review the qualifications and characteristics of the classification systems. They evaluated performance objectives, developed waste classification tables, and compiled dose limits on the waste. A goal of the LLW classification system was to allow each disposal site the freedom to develop limits to radionuclide inventories and concentrations according to its own site-specific characteristics. This goal was achieved with the adoption of a performance objectives system based on a performance assessment, with site-specific environmental conditions and engineered disposal systems

  10. Constructing criticality by classification

    DEFF Research Database (Denmark)

    Machacek, Erika

    2017-01-01

    " in the bureaucratic practice of classification: Experts construct material criticality in assessments as they allot information on the materials to the parameters of the assessment framework. In so doing, they ascribe a new set of connotations to the materials, namely supply risk, and their importance to clean energy......, legitimizing a criticality discourse.Specifically, the paper introduces a typology delineating the inferences made by the experts from their produced recommendations in the classification of rare earth element criticality. The paper argues that the classification is a specific process of constructing risk....... It proposes that the expert bureaucratic practice of classification legitimizes (i) the valorisation that was made in the drafting of the assessment framework for the classification, and (ii) political operationalization when enacted that might have (non-)distributive implications for the allocation of public...

  11. Biological Agents

    Science.gov (United States)

    ... E-Tools Safety and Health Topics / Biological Agents Biological Agents This page requires that javascript be enabled ... 202) 693-2300 if additional assistance is required. Biological Agents Menu Overview In Focus: Ebola Frederick A. ...

  12. DTI measurements for Alzheimer’s classification

    Science.gov (United States)

    Maggipinto, Tommaso; Bellotti, Roberto; Amoroso, Nicola; Diacono, Domenico; Donvito, Giacinto; Lella, Eufemia; Monaco, Alfonso; Antonella Scelsi, Marzia; Tangaro, Sabina; Disease Neuroimaging Initiative, Alzheimer's.

    2017-03-01

    Diffusion tensor imaging (DTI) is a promising imaging technique that provides insight into white matter microstructure integrity and it has greatly helped identifying white matter regions affected by Alzheimer’s disease (AD) in its early stages. DTI can therefore be a valuable source of information when designing machine-learning strategies to discriminate between healthy control (HC) subjects, AD patients and subjects with mild cognitive impairment (MCI). Nonetheless, several studies have reported so far conflicting results, especially because of the adoption of biased feature selection strategies. In this paper we firstly analyzed DTI scans of 150 subjects from the Alzheimer’s disease neuroimaging initiative (ADNI) database. We measured a significant effect of the feature selection bias on the classification performance (p-value  informative content provided by DTI measurements for AD classification. Classification performances and biological insight, concerning brain regions related to the disease, provided by cross-validation analysis were both confirmed on the independent test.

  13. River reach classification for the Greater Mekong Region at high spatial resolution

    Science.gov (United States)

    Ouellet Dallaire, C.; Lehner, B.

    2014-12-01

    River classifications have been used in river health and ecological assessments as coarse proxies to represent aquatic biodiversity when comprehensive biological and/or species data is unavailable. Currently there are no river classifications or biological data available in a consistent format for the extent of the Greater Mekong Region (GMR; including the Irrawaddy, the Salween, the Chao Praya, the Mekong and the Red River basins). The current project proposes a new river habitat classification for the region, facilitated by the HydroSHEDS (HYDROlogical SHuttle Elevation Derivatives at multiple Scales) database at 500m pixel resolution. The classification project is based on the Global River Classification framework relying on the creation of multiple sub-classifications based on different disciplines. The resulting classes from the sub-classification are later combined into final classes to create a holistic river reach classification. For the GMR, a final habitat classification was created based on three sub-classifications: a hydrological sub-classification based only on discharge indices (river size and flow variability); a physio-climatic sub-classification based on large scale indices of climate and elevation (biomes, ecoregions and elevation); and a geomorphological sub-classification based on local morphology (presence of floodplains, reach gradient and sand transport). Key variables and thresholds were identified in collaboration with local experts to ensure that regional knowledge was included. The final classification is composed 54 unique final classes based on 3 sub-classifications with less than 15 classes each. The resulting classifications are driven by abiotic variables and do not include biological data, but they represent a state-of-the art product based on best available data (mostly global data). The most common river habitat type is the "dry broadleaf, low gradient, very small river". These classifications could be applied in a wide range of

  14. Classification of movement disorders.

    Science.gov (United States)

    Fahn, Stanley

    2011-05-01

    The classification of movement disorders has evolved. Even the terminology has shifted, from an anatomical one of extrapyramidal disorders to a phenomenological one of movement disorders. The history of how this shift came about is described. The history of both the definitions and the classifications of the various neurologic conditions is then reviewed. First is a review of movement disorders as a group; then, the evolving classifications for 3 of them--parkinsonism, dystonia, and tremor--are covered in detail. Copyright © 2011 Movement Disorder Society.

  15. Biogeographic classification of the Caspian Sea

    DEFF Research Database (Denmark)

    Fendereski, F.; Vogt, M.; Payne, Mark

    2014-01-01

    Like other inland seas, the Caspian Sea (CS) has been influenced by climate change and anthropogenic disturbance during recent decades, yet the scientific understanding of this water body remains poor. In this study, an eco-geographical classification of the CS based on physical information deriv...... confirms the relevance of the ecoregions as proxies for habitats with common biological characteristics....... from space and in-situ data is developed and tested against a set of biological observations. We used a two-step classification procedure, consisting of (i) a data reduction with self-organizing maps (SOMs) and (ii) a synthesis of the most relevant features into a reduced number of marine ecoregions...... in phytoplankton phenology, with differences in the date of bloom initiation, its duration and amplitude between ecoregions. A first qualitative evaluation of differences in community composition based on recorded presence-absence patterns of 27 different species of plankton, fish and benthic invertebrate also...

  16. Destratification efficiency by hypolimnitic water lifter with air bullets. Kihodan wo mochiita shinsosui yosui shisetsu ni yoru mitsudo seiso no kongo koritsu

    Energy Technology Data Exchange (ETDEWEB)

    Ikeda, H; Suga, K [Utsunomiya University, Tochigi (Japan). Faculty of Engineering; Asaeda, T [Saitama University, Saitama (Japan). Faculty of Engineering

    1994-02-21

    The intermittent aeration and circulation method is used frequently to destruct temperature stratification in a reservoir to prevent it from eutrophication. This method uses a cylinder erected in water, into which air bullets are shot out intermittently to circulate and mix heavier water mass upward. The present study has performed numerical analysis on the process to mix density stratifications by operating an intermittent water lifter cylinder for an extended period of time, and discussed responses of each factor to variation. The numerical computation has been carried out according to the equation of motion for water and air in the water lifter cylinder, and the numerical model that hypothesizes the double plume after air bubbles have departed from the water lifter cylinder. The result indicated that the amount of hypolimnitic water lifted against the amount of air injected can be expressed by an empirical formula that uses only the relative air bullet volumes. An evaluation formula for the water lifting efficiency has also been derived. It has been found for the stratification mixing that trends in the mixing efficiency can be identified by two parameters of dimensionless air bubble amount and stratification strength. 17 refs., 11 figs., 4 tabs.

  17. Filamentation and light bullet formation dynamics in solid-state dielectric media with weak, moderate and strong anomalous group velocity dispersion

    International Nuclear Information System (INIS)

    Gražulevičiūtė, I; Garejev, N; Majus, D; Tamošauskas, G; A Dubietis; Jukna, V

    2016-01-01

    We present a series of measurements, which characterize filamentation dynamics of intense ultrashort laser pulses in the space–time domain, as captured by means of three-dimensional imaging technique in sapphire and fused silica, in the wavelength range of 1.45–2.25 μm, accessing the regimes of weak, moderate and strong anomalous group velocity dispersion (GVD). In the regime of weak anomalous GVD (at 1.45 μm), pulse splitting into two sub-pulses producing a pair of light bullets with spectrally shifted carrier frequencies in both nonlinear media is observed. In contrast, in the regimes of moderate (at 1.8 μm) and strong (at 2.25 μm) anomalous GVD we observe notably different transient dynamics, which however lead to the formation of a single self-compressed quasistationary light bullet with an universal spatiotemporal shape comprised of an extended ring-shaped periphery and a localized intense core that carries the self-compressed pulse. (paper)

  18. Filamentation and light bullet formation dynamics in solid-state dielectric media with weak, moderate and strong anomalous group velocity dispersion

    Science.gov (United States)

    Gražulevičiūtė, I.; Garejev, N.; Majus, D.; Jukna, V.; Tamošauskas, G.; Dubietis, A.

    2016-02-01

    We present a series of measurements, which characterize filamentation dynamics of intense ultrashort laser pulses in the space-time domain, as captured by means of three-dimensional imaging technique in sapphire and fused silica, in the wavelength range of 1.45-2.25 μm, accessing the regimes of weak, moderate and strong anomalous group velocity dispersion (GVD). In the regime of weak anomalous GVD (at 1.45 μm), pulse splitting into two sub-pulses producing a pair of light bullets with spectrally shifted carrier frequencies in both nonlinear media is observed. In contrast, in the regimes of moderate (at 1.8 μm) and strong (at 2.25 μm) anomalous GVD we observe notably different transient dynamics, which however lead to the formation of a single self-compressed quasistationary light bullet with an universal spatiotemporal shape comprised of an extended ring-shaped periphery and a localized intense core that carries the self-compressed pulse.

  19. Update on diabetes classification.

    Science.gov (United States)

    Thomas, Celeste C; Philipson, Louis H

    2015-01-01

    This article highlights the difficulties in creating a definitive classification of diabetes mellitus in the absence of a complete understanding of the pathogenesis of the major forms. This brief review shows the evolving nature of the classification of diabetes mellitus. No classification scheme is ideal, and all have some overlap and inconsistencies. The only diabetes in which it is possible to accurately diagnose by DNA sequencing, monogenic diabetes, remains undiagnosed in more than 90% of the individuals who have diabetes caused by one of the known gene mutations. The point of classification, or taxonomy, of disease, should be to give insight into both pathogenesis and treatment. It remains a source of frustration that all schemes of diabetes mellitus continue to fall short of this goal. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Learning Apache Mahout classification

    CERN Document Server

    Gupta, Ashish

    2015-01-01

    If you are a data scientist who has some experience with the Hadoop ecosystem and machine learning methods and want to try out classification on large datasets using Mahout, this book is ideal for you. Knowledge of Java is essential.

  1. CLASSIFICATION OF VIRUSES

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. CLASSIFICATION OF VIRUSES. On basis of morphology. On basis of chemical composition. On basis of structure of genome. On basis of mode of replication. Notes:

  2. Pitch Based Sound Classification

    DEFF Research Database (Denmark)

    Nielsen, Andreas Brinch; Hansen, Lars Kai; Kjems, U

    2006-01-01

    A sound classification model is presented that can classify signals into music, noise and speech. The model extracts the pitch of the signal using the harmonic product spectrum. Based on the pitch estimate and a pitch error measure, features are created and used in a probabilistic model with soft......-max output function. Both linear and quadratic inputs are used. The model is trained on 2 hours of sound and tested on publicly available data. A test classification error below 0.05 with 1 s classification windows is achieved. Further more it is shown that linear input performs as well as a quadratic......, and that even though classification gets marginally better, not much is achieved by increasing the window size beyond 1 s....

  3. Problems of classification in the family Paramyxoviridae.

    Science.gov (United States)

    Rima, Bert; Collins, Peter; Easton, Andrew; Fouchier, Ron; Kurath, Gael; Lamb, Robert A; Lee, Benhur; Maisner, Andrea; Rota, Paul; Wang, Lin-Fa

    2018-05-01

    A number of unassigned viruses in the family Paramyxoviridae need to be classified either as a new genus or placed into one of the seven genera currently recognized in this family. Furthermore, numerous new paramyxoviruses continue to be discovered. However, attempts at classification have highlighted the difficulties that arise by applying historic criteria or criteria based on sequence alone to the classification of the viruses in this family. While the recent taxonomic change that elevated the previous subfamily Pneumovirinae into a separate family Pneumoviridae is readily justified on the basis of RNA dependent -RNA polymerase (RdRp or L protein) sequence motifs, using RdRp sequence comparisons for assignment to lower level taxa raises problems that would require an overhaul of the current criteria for assignment into genera in the family Paramyxoviridae. Arbitrary cut off points to delineate genera and species would have to be set if classification was based on the amino acid sequence of the RdRp alone or on pairwise analysis of sequence complementarity (PASC) of all open reading frames (ORFs). While these cut-offs cannot be made consistent with the current classification in this family, resorting to genus-level demarcation criteria with additional input from the biological context may afford a way forward. Such criteria would reflect the increasingly dynamic nature of virus taxonomy even if it would require a complete revision of the current classification.

  4. Genome-Wide Comparative Gene Family Classification

    Science.gov (United States)

    Frech, Christian; Chen, Nansheng

    2010-01-01

    Correct classification of genes into gene families is important for understanding gene function and evolution. Although gene families of many species have been resolved both computationally and experimentally with high accuracy, gene family classification in most newly sequenced genomes has not been done with the same high standard. This project has been designed to develop a strategy to effectively and accurately classify gene families across genomes. We first examine and compare the performance of computer programs developed for automated gene family classification. We demonstrate that some programs, including the hierarchical average-linkage clustering algorithm MC-UPGMA and the popular Markov clustering algorithm TRIBE-MCL, can reconstruct manual curation of gene families accurately. However, their performance is highly sensitive to parameter setting, i.e. different gene families require different program parameters for correct resolution. To circumvent the problem of parameterization, we have developed a comparative strategy for gene family classification. This strategy takes advantage of existing curated gene families of reference species to find suitable parameters for classifying genes in related genomes. To demonstrate the effectiveness of this novel strategy, we use TRIBE-MCL to classify chemosensory and ABC transporter gene families in C. elegans and its four sister species. We conclude that fully automated programs can establish biologically accurate gene families if parameterized accordingly. Comparative gene family classification finds optimal parameters automatically, thus allowing rapid insights into gene families of newly sequenced species. PMID:20976221

  5. Towards secondary fingerprint classification

    CSIR Research Space (South Africa)

    Msiza, IS

    2011-07-01

    Full Text Available an accuracy figure of 76.8%. This small difference between the two figures is indicative of the validity of the proposed secondary classification module. Keywords?fingerprint core; fingerprint delta; primary classifi- cation; secondary classification I..., namely, the fingerprint core and the fingerprint delta. Forensically, a fingerprint core is defined as the innermost turning point where the fingerprint ridges form a loop, while the fingerprint delta is defined as the point where these ridges form a...

  6. Expected Classification Accuracy

    Directory of Open Access Journals (Sweden)

    Lawrence M. Rudner

    2005-08-01

    Full Text Available Every time we make a classification based on a test score, we should expect some number..of misclassifications. Some examinees whose true ability is within a score range will have..observed scores outside of that range. A procedure for providing a classification table of..true and expected scores is developed for polytomously scored items under item response..theory and applied to state assessment data. A simplified procedure for estimating the..table entries is also presented.

  7. Latent classification models

    DEFF Research Database (Denmark)

    Langseth, Helge; Nielsen, Thomas Dyhre

    2005-01-01

    parametric family ofdistributions.  In this paper we propose a new set of models forclassification in continuous domains, termed latent classificationmodels. The latent classification model can roughly be seen ascombining the \\NB model with a mixture of factor analyzers,thereby relaxing the assumptions...... classification model, and wedemonstrate empirically that the accuracy of the proposed model issignificantly higher than the accuracy of other probabilisticclassifiers....

  8. 78 FR 68983 - Cotton Futures Classification: Optional Classification Procedure

    Science.gov (United States)

    2013-11-18

    ...-AD33 Cotton Futures Classification: Optional Classification Procedure AGENCY: Agricultural Marketing... regulations to allow for the addition of an optional cotton futures classification procedure--identified and... response to requests from the U.S. cotton industry and ICE, AMS will offer a futures classification option...

  9. Supernova Photometric Lightcurve Classification

    Science.gov (United States)

    Zaidi, Tayeb; Narayan, Gautham

    2016-01-01

    This is a preliminary report on photometric supernova classification. We first explore the properties of supernova light curves, and attempt to restructure the unevenly sampled and sparse data from assorted datasets to allow for processing and classification. The data was primarily drawn from the Dark Energy Survey (DES) simulated data, created for the Supernova Photometric Classification Challenge. This poster shows a method for producing a non-parametric representation of the light curve data, and applying a Random Forest classifier algorithm to distinguish between supernovae types. We examine the impact of Principal Component Analysis to reduce the dimensionality of the dataset, for future classification work. The classification code will be used in a stage of the ANTARES pipeline, created for use on the Large Synoptic Survey Telescope alert data and other wide-field surveys. The final figure-of-merit for the DES data in the r band was 60% for binary classification (Type I vs II).Zaidi was supported by the NOAO/KPNO Research Experiences for Undergraduates (REU) Program which is funded by the National Science Foundation Research Experiences for Undergraduates Program (AST-1262829).

  10. A New Classification Approach Based on Multiple Classification Rules

    OpenAIRE

    Zhongmei Zhou

    2014-01-01

    A good classifier can correctly predict new data for which the class label is unknown, so it is important to construct a high accuracy classifier. Hence, classification techniques are much useful in ubiquitous computing. Associative classification achieves higher classification accuracy than some traditional rule-based classification approaches. However, the approach also has two major deficiencies. First, it generates a very large number of association classification rules, especially when t...

  11. Bread and bullets

    OpenAIRE

    Akerlof, George A.; Snower, Dennis J.

    2016-01-01

    Standard economics omits the role of narratives (the stories that people tell themselves and others) when they make all kinds of decisions. Narratives play a role in understanding the environment; focusing attention; predicting events; motivating action; assigning social roles and identities; defining power relations; and establishing and conveying social norms. This paper describes the role narratives play in decision making, as it also juxtaposes this description against the backdrop of the...

  12. Racial classification in the evolutionary sciences: a comparative analysis.

    Science.gov (United States)

    Billinger, Michael S

    2007-01-01

    Human racial classification has long been a problem for the discipline of anthropology, but much of the criticism of the race concept has focused on its social and political connotations. The central argument of this paper is that race is not a specifically human problem, but one that exists in evolutionary thought in general. This paper looks at various disciplinary approaches to racial or subspecies classification, extending its focus beyond the anthropological race concept by providing a comparative analysis of the use of racial classification in evolutionary biology, genetics, and anthropology.

  13. Modern Biology

    OpenAIRE

    ALEKSIC, Branko

    2014-01-01

    The purpose of this course is to learn the philosophy, principles, and techniques of modern biology. The course is particularly designed for those who have not learned biology previously or whose major is other than biology, and who may think that they do not need to know any biology at all. The topics are covered in a rather general, overview manner, but certain level of diligence in grasping concepts and memorizing the terminology is expected.

  14. Cellular image classification

    CERN Document Server

    Xu, Xiang; Lin, Feng

    2017-01-01

    This book introduces new techniques for cellular image feature extraction, pattern recognition and classification. The authors use the antinuclear antibodies (ANAs) in patient serum as the subjects and the Indirect Immunofluorescence (IIF) technique as the imaging protocol to illustrate the applications of the described methods. Throughout the book, the authors provide evaluations for the proposed methods on two publicly available human epithelial (HEp-2) cell datasets: ICPR2012 dataset from the ICPR'12 HEp-2 cell classification contest and ICIP2013 training dataset from the ICIP'13 Competition on cells classification by fluorescent image analysis. First, the reading of imaging results is significantly influenced by one’s qualification and reading systems, causing high intra- and inter-laboratory variance. The authors present a low-order LP21 fiber mode for optical single cell manipulation and imaging staining patterns of HEp-2 cells. A focused four-lobed mode distribution is stable and effective in optical...

  15. Bosniak classification system

    DEFF Research Database (Denmark)

    Graumann, Ole; Osther, Susanne Sloth; Karstoft, Jens

    2016-01-01

    BACKGROUND: The Bosniak classification was originally based on computed tomographic (CT) findings. Magnetic resonance (MR) and contrast-enhanced ultrasonography (CEUS) imaging may demonstrate findings that are not depicted at CT, and there may not always be a clear correlation between the findings...... at MR and CEUS imaging and those at CT. PURPOSE: To compare diagnostic accuracy of MR, CEUS, and CT when categorizing complex renal cystic masses according to the Bosniak classification. MATERIAL AND METHODS: From February 2011 to June 2012, 46 complex renal cysts were prospectively evaluated by three...... readers. Each mass was categorized according to the Bosniak classification and CT was chosen as gold standard. Kappa was calculated for diagnostic accuracy and data was compared with pathological results. RESULTS: CT images found 27 BII, six BIIF, seven BIII, and six BIV. Forty-three cysts could...

  16. Bosniak Classification system

    DEFF Research Database (Denmark)

    Graumann, Ole; Osther, Susanne Sloth; Karstoft, Jens

    2014-01-01

    Background: The Bosniak classification is a diagnostic tool for the differentiation of cystic changes in the kidney. The process of categorizing renal cysts may be challenging, involving a series of decisions that may affect the final diagnosis and clinical outcome such as surgical management....... Purpose: To investigate the inter- and intra-observer agreement among experienced uroradiologists when categorizing complex renal cysts according to the Bosniak classification. Material and Methods: The original categories of 100 cystic renal masses were chosen as “Gold Standard” (GS), established...... to the calculated weighted κ all readers performed “very good” for both inter-observer and intra-observer variation. Most variation was seen in cysts catagorized as Bosniak II, IIF, and III. These results show that radiologists who evaluate complex renal cysts routinely may apply the Bosniak classification...

  17. Acoustic classification of dwellings

    DEFF Research Database (Denmark)

    Berardi, Umberto; Rasmussen, Birgit

    2014-01-01

    insulation performance, national schemes for sound classification of dwellings have been developed in several European countries. These schemes define acoustic classes according to different levels of sound insulation. Due to the lack of coordination among countries, a significant diversity in terms...... exchanging experiences about constructions fulfilling different classes, reducing trade barriers, and finally increasing the sound insulation of dwellings.......Schemes for the classification of dwellings according to different building performances have been proposed in the last years worldwide. The general idea behind these schemes relates to the positive impact a higher label, and thus a better performance, should have. In particular, focusing on sound...

  18. Minimum Error Entropy Classification

    CERN Document Server

    Marques de Sá, Joaquim P; Santos, Jorge M F; Alexandre, Luís A

    2013-01-01

    This book explains the minimum error entropy (MEE) concept applied to data classification machines. Theoretical results on the inner workings of the MEE concept, in its application to solving a variety of classification problems, are presented in the wider realm of risk functionals. Researchers and practitioners also find in the book a detailed presentation of practical data classifiers using MEE. These include multi‐layer perceptrons, recurrent neural networks, complexvalued neural networks, modular neural networks, and decision trees. A clustering algorithm using a MEE‐like concept is also presented. Examples, tests, evaluation experiments and comparison with similar machines using classic approaches, complement the descriptions.

  19. Classification of iconic images

    OpenAIRE

    Zrianina, Mariia; Kopf, Stephan

    2016-01-01

    Iconic images represent an abstract topic and use a presentation that is intuitively understood within a certain cultural context. For example, the abstract topic “global warming” may be represented by a polar bear standing alone on an ice floe. Such images are widely used in media and their automatic classification can help to identify high-level semantic concepts. This paper presents a system for the classification of iconic images. It uses a variation of the Bag of Visual Words approach wi...

  20. Casemix classification systems.

    Science.gov (United States)

    Fetter, R B

    1999-01-01

    The idea of using casemix classification to manage hospital services is not new, but has been limited by available technology. It was not until after the introduction of Medicare in the United States in 1965 that serious attempts were made to measure hospital production in order to contain spiralling costs. This resulted in a system of casemix classification known as diagnosis related groups (DRGs). This paper traces the development of DRGs and their evolution from the initial version to the All Patient Refined DRGs developed in 1991.

  1. Information gathering for CLP classification

    Directory of Open Access Journals (Sweden)

    Ida Marcello

    2011-01-01

    Full Text Available Regulation 1272/2008 includes provisions for two types of classification: harmonised classification and self-classification. The harmonised classification of substances is decided at Community level and a list of harmonised classifications is included in the Annex VI of the classification, labelling and packaging Regulation (CLP. If a chemical substance is not included in the harmonised classification list it must be self-classified, based on available information, according to the requirements of Annex I of the CLP Regulation. CLP appoints that the harmonised classification will be performed for carcinogenic, mutagenic or toxic to reproduction substances (CMR substances and for respiratory sensitisers category 1 and for other hazard classes on a case-by-case basis. The first step of classification is the gathering of available and relevant information. This paper presents the procedure for gathering information and to obtain data. The data quality is also discussed.

  2. The paradox of atheoretical classification

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2016-01-01

    A distinction can be made between “artificial classifications” and “natural classifications,” where artificial classifications may adequately serve some limited purposes, but natural classifications are overall most fruitful by allowing inference and thus many different purposes. There is strong...... support for the view that a natural classification should be based on a theory (and, of course, that the most fruitful theory provides the most fruitful classification). Nevertheless, atheoretical (or “descriptive”) classifications are often produced. Paradoxically, atheoretical classifications may...... be very successful. The best example of a successful “atheoretical” classification is probably the prestigious Diagnostic and Statistical Manual of Mental Disorders (DSM) since its third edition from 1980. Based on such successes one may ask: Should the claim that classifications ideally are natural...

  3. Bone-patch type secondary projectiles: A report on two shots fired at point-blank range using hollow point bullets.

    Science.gov (United States)

    Malbranque, S; Jousset, N; Nedelcu, C; Rougé-Maillart, C

    2014-12-01

    The number of head wounds due to firearms remains low in France because these cases are primarily linked to suicide (or attempted suicide) and, to a lesser extent, to attacks or hunting accidents [1]. Characterized by the impact of a projectile, which in most cases is made of metal, at high levels of kinetic energy, such acts generally result in severe trans-cerebral lesions with significant levels of morbidity/mortality [2]. Seldom are cases reported in the literature that give a detailed study of intracranial foreign bodies made of bone in such situations [3]. Here we report on the case of two suicides resulting from a transcranial gunshot wounds caused by weapons and ammunition issued by the French police force. Each case helped distinguish a characteristic bone fragment, in the form of a "patch", equivalent in size to the caliber of the bullet. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  4. Mitochondrial genome of the bullet tuna Auxis rochei from Indo-West Pacific collection provides novel genetic information about two subspecies.

    Science.gov (United States)

    Li, Mingming; Guo, Liang; Zhang, Heng; Yang, Sen; Chen, Xinghan; Lin, Haoran; Meng, Zining

    2016-09-01

    Previously morphological studies supported the division of the bullet tuna into the two subspecies, Auxis rochei rochei and A. rochei eudorax. As a cosmopolitan species, A. rochei rochei ranges in the Indo-West Pacific and Atlantic oceans, while A. rochei eudorax inhabits in eastern Pacific region. Here, we used the HiSeq next-generation sequencing technique to determine the mitochondrial genome (mitogenome) of A. rochei from Indo-West Pacific collection, and then compared our data with mitogenomic sequences of the Atlantic and eastern Pacific retrieved from NCBI database. Results showed the mitogenome of A. rochei from three geographic collections shared the same genes and gene order, similar to typical teleosts. Also, we examined a low level of nucleotide diversity among these mitogenomic sequences. Interestingly, nucleotide diversity of intra-subspecies (Atlantic versus Indo-West) was higher than that of inter-subspecies (Atlantic versus eastern Pacific, Indo-West versus eastern Pacific).

  5. Penetrating gunshot wound to the head: transotic approach to remove the bullet and masseteric-facial nerve anastomosis for early facial reanimation.

    Science.gov (United States)

    Donnarumma, Pasquale; Tarantino, Roberto; Gennaro, Paolo; Mitro, Valeria; Valentini, Valentino; Magliulo, Giuseppe; Delfini, Roberto

    2014-01-01

    Gunshot wounds to the head (GSWH) account for the majority of penetrating brain injuries, and are the most lethal. Since they are rare in Europe, the number of neurosurgeons who have experienced this type of traumatic injury is decreasing, and fewer cases are reported in the literature. We describe a case of gunshot to the temporal bone in which the bullet penetrated the skull resulting in the facial nerve paralysis. It was excised with the transotic approach. Microsurgical anastomosis among the masseteric nerve and the facial nerve was performed. GSWH are often devastating. The in-hospital mortality for civilians with penetrating craniocerebral injury is very high. Survivors often have high rate of complications. When facial paralysis is present, masseteric-facial direct neurorraphy represent a good treatment.

  6. Impact analysis of side door of a car and bullet proof vest with material ‘SAM2X5-630’ using finite element analysis

    Science.gov (United States)

    Dhode, Trushant; Patil, Girish; Rajkumar, E.

    2017-11-01

    The components which are bound to impact are subjected to deformation even though it may be for a small scale. The efforts are always on for finding the best material to take impact that has no failure or moreover, less plastic deformation. A newly found material which is glass matrix steel named as ‘SAM2X5-630’ has astounding high elastic limit of 12.5GPa. Thus it can take powerful impact & regain its original shape avoiding the deformation of component under impact. The paper is focused on performing the Finite element analysis to assess the behaviour of ‘SAM2X5-630’ steel under impact loading of side door of car as well as impact of bullet on bulletproof jacket on which the material is assigned. The displacement or deformation occurred during impact is found to be lesser than known materials like Kevlar in bulletproof vest and Aluminium alloy in car door.

  7. Mathematical biology

    CERN Document Server

    Murray, James D

    1993-01-01

    The book is a textbook (with many exercises) giving an in-depth account of the practical use of mathematical modelling in the biomedical sciences. The mathematical level required is generally not high and the emphasis is on what is required to solve the real biological problem. The subject matter is drawn, e.g. from population biology, reaction kinetics, biological oscillators and switches, Belousov-Zhabotinskii reaction, reaction-diffusion theory, biological wave phenomena, central pattern generators, neural models, spread of epidemics, mechanochemical theory of biological pattern formation and importance in evolution. Most of the models are based on real biological problems and the predictions and explanations offered as a direct result of mathematical analysis of the models are important aspects of the book. The aim is to provide a thorough training in practical mathematical biology and to show how exciting and novel mathematical challenges arise from a genuine interdisciplinary involvement with the biosci...

  8. Rate constants and temperature effects for reactions of Cl2sm-bullet- with unsaturated alcohols and hydrocarbons in aqueous and acetonitrile/water solutions

    International Nuclear Information System (INIS)

    Padmaja, S.; Neta, P.; Huie, R.E.

    1992-01-01

    Absolute rate constants for reactions of the dichlorine radical anion, Cl 2 sm-bullet- , with unsaturated alcohols and hydrocarbons have been measured at various temperatures. The alcohol reactions were measured in aqueous solutions and the hydrocarbon reactions in 1:1 aqueous acetonitirle (ACN) solutions. The rate constants for two alcohols and one hydrocarbon were also examined as a function of solvent composition. The room temperature rate constants varied between 10 6 and 10 9 M -1 s -1 . The pre-exponential factors, A, were about (1-5) x 10 9 M -1 s -1 for the alcohols in aqueous solutions and about (0.1-1) x 10 9 M -1 s -1 for the hydrocarbons in aqueous ACN solutions. The activation energies, E a , varied considerably, between 4 and 12 kJ mol -1 for the alcohols and between 2 and 8 kJ mol -1 for the hydrocarbons. The rate constants, k 298 , decrease with increasing ionization potential (IP) of the unsaturated compound, in agreement with an electrophilic addition mechanism. The activation energies for the unsaturated alcohols decrease when the IP decreases from 9.7 to 9.1 eV but appear to level off at lower IP. Most alkenes studied had IP a . Upon addition of ACN to the aqueous solution, the values of log k 298 decreased linearly by more than 1 order of magnitude with increasing ACN mole fraction. This decrease appears to result from a combination of changes in the activation energy and in the pre-exponential factor. The reason for these changes may lie in changes in the solvation shell of the Cl 2 sm-bullet- radical, which will affect the A factor, in combination with changes in solvation of Cl - , which will affect the energetics of the reactions as well. 20 refs., 7 figs., 6 tabs

  9. Ecosystem classification, Chapter 2

    Science.gov (United States)

    M.J. Robin-Abbott; L.H. Pardo

    2011-01-01

    The ecosystem classification in this report is based on the ecoregions developed through the Commission for Environmental Cooperation (CEC) for North America (CEC 1997). Only ecosystems that occur in the United States are included. CEC ecoregions are described, with slight modifications, below (CEC 1997) and shown in Figures 2.1 and 2.2. We chose this ecosystem...

  10. The classification of phocomelia.

    Science.gov (United States)

    Tytherleigh-Strong, G; Hooper, G

    2003-06-01

    We studied 24 patients with 44 phocomelic upper limbs. Only 11 limbs could be grouped in the classification system of Frantz and O' Rahilly. The non-classifiable limbs were further studied and their characteristics identified. It is confirmed that phocomelia is not an intercalary defect.

  11. Principles for ecological classification

    Science.gov (United States)

    Dennis H. Grossman; Patrick Bourgeron; Wolf-Dieter N. Busch; David T. Cleland; William Platts; G. Ray; C. Robins; Gary Roloff

    1999-01-01

    The principal purpose of any classification is to relate common properties among different entities to facilitate understanding of evolutionary and adaptive processes. In the context of this volume, it is to facilitate ecosystem stewardship, i.e., to help support ecosystem conservation and management objectives.

  12. Mimicking human texture classification

    NARCIS (Netherlands)

    Rogowitz, B.E.; van Rikxoort, Eva M.; van den Broek, Egon; Pappas, T.N.; Schouten, Theo E.; Daly, S.J.

    2005-01-01

    In an attempt to mimic human (colorful) texture classification by a clustering algorithm three lines of research have been encountered, in which as test set 180 texture images (both their color and gray-scale equivalent) were drawn from the OuTex and VisTex databases. First, a k-means algorithm was

  13. Classification, confusion and misclassification

    African Journals Online (AJOL)

    The classification of objects and phenomena in science and nature has fascinated academics since Carl Linnaeus, the Swedish botanist and zoologist, created his binomial description of living things in the 1700s and probably long before in accounts of others in textbooks long since gone. It must have concerned human ...

  14. Classifications in popular music

    NARCIS (Netherlands)

    van Venrooij, A.; Schmutz, V.; Wright, J.D.

    2015-01-01

    The categorical system of popular music, such as genre categories, is a highly differentiated and dynamic classification system. In this article we present work that studies different aspects of these categorical systems in popular music. Following the work of Paul DiMaggio, we focus on four

  15. Shark Teeth Classification

    Science.gov (United States)

    Brown, Tom; Creel, Sally; Lee, Velda

    2009-01-01

    On a recent autumn afternoon at Harmony Leland Elementary in Mableton, Georgia, students in a fifth-grade science class investigated the essential process of classification--the act of putting things into groups according to some common characteristics or attributes. While they may have honed these skills earlier in the week by grouping their own…

  16. Text document classification

    Czech Academy of Sciences Publication Activity Database

    Novovičová, Jana

    č. 62 (2005), s. 53-54 ISSN 0926-4981 R&D Projects: GA AV ČR IAA2075302; GA AV ČR KSK1019101; GA MŠk 1M0572 Institutional research plan: CEZ:AV0Z10750506 Keywords : document representation * categorization * classification Subject RIV: BD - Theory of Information

  17. Classification in Medical Imaging

    DEFF Research Database (Denmark)

    Chen, Chen

    Classification is extensively used in the context of medical image analysis for the purpose of diagnosis or prognosis. In order to classify image content correctly, one needs to extract efficient features with discriminative properties and build classifiers based on these features. In addition...... on characterizing human faces and emphysema disease in lung CT images....

  18. Improving Student Question Classification

    Science.gov (United States)

    Heiner, Cecily; Zachary, Joseph L.

    2009-01-01

    Students in introductory programming classes often articulate their questions and information needs incompletely. Consequently, the automatic classification of student questions to provide automated tutorial responses is a challenging problem. This paper analyzes 411 questions from an introductory Java programming course by reducing the natural…

  19. NOUN CLASSIFICATION IN ESAHIE

    African Journals Online (AJOL)

    The present work deals with noun classification in Esahie (Kwa, Niger ... phonological information influences the noun (form) class system of Esahie. ... between noun classes and (grammatical) Gender is interrogated (in the light of ..... the (A) argument6 precedes the verb and the (P) argument7 follows the verb in a simple.

  20. Dynamic Latent Classification Model

    DEFF Research Database (Denmark)

    Zhong, Shengtong; Martínez, Ana M.; Nielsen, Thomas Dyhre

    as possible. Motivated by this problem setting, we propose a generative model for dynamic classification in continuous domains. At each time point the model can be seen as combining a naive Bayes model with a mixture of factor analyzers (FA). The latent variables of the FA are used to capture the dynamics...

  1. Classification of myocardial infarction

    DEFF Research Database (Denmark)

    Saaby, Lotte; Poulsen, Tina Svenstrup; Hosbond, Susanne Elisabeth

    2013-01-01

    The classification of myocardial infarction into 5 types was introduced in 2007 as an important component of the universal definition. In contrast to the plaque rupture-related type 1 myocardial infarction, type 2 myocardial infarction is considered to be caused by an imbalance between demand...

  2. Event Classification using Concepts

    NARCIS (Netherlands)

    Boer, M.H.T. de; Schutte, K.; Kraaij, W.

    2013-01-01

    The semantic gap is one of the challenges in the GOOSE project. In this paper a Semantic Event Classification (SEC) system is proposed as an initial step in tackling the semantic gap challenge in the GOOSE project. This system uses semantic text analysis, multiple feature detectors using the BoW

  3. NEW CLASSIFICATION OF ECOPOLICES

    Directory of Open Access Journals (Sweden)

    VOROBYOV V. V.

    2016-09-01

    Full Text Available Problem statement. Ecopolices are the newest stage of the urban planning. They have to be consideredsuchas material and energy informational structures, included to the dynamic-evolutionary matrix netsofex change processes in the ecosystems. However, there are not made the ecopolice classifications, developing on suchapproaches basis. And this determined the topicality of the article. Analysis of publications on theoretical and applied aspects of the ecopolices formation showed, that the work on them is managed mainly in the context of the latest scientific and technological achievements in the various knowledge fields. These settlements are technocratic. They are connected with the morphology of space, network structures of regional and local natural ecosystems, without independent stability, can not exist without continuous man support. Another words, they do not work in with an ecopolices idea. It is come to a head for objective, symbiotic searching of ecopolices concept with the development of their classifications. Purpose statement is to develop the objective evidence for ecopolices and to propose their new classification. Conclusion. On the base of the ecopolices classification have to lie an elements correlation idea of their general plans and men activity type according with natural mechanism of accepting, reworking and transmission of material, energy and information between geo-ecosystems, planet, man, ecopolices material part and Cosmos. New ecopolices classification should be based on the principles of multi-dimensional, time-spaced symbiotic clarity with exchange ecosystem networks. The ecopolice function with this approach comes not from the subjective anthropocentric economy but from the holistic objective of Genesis paradigm. Or, otherwise - not from the Consequence, but from the Cause.

  4. Efficient Fingercode Classification

    Science.gov (United States)

    Sun, Hong-Wei; Law, Kwok-Yan; Gollmann, Dieter; Chung, Siu-Leung; Li, Jian-Bin; Sun, Jia-Guang

    In this paper, we present an efficient fingerprint classification algorithm which is an essential component in many critical security application systems e. g. systems in the e-government and e-finance domains. Fingerprint identification is one of the most important security requirements in homeland security systems such as personnel screening and anti-money laundering. The problem of fingerprint identification involves searching (matching) the fingerprint of a person against each of the fingerprints of all registered persons. To enhance performance and reliability, a common approach is to reduce the search space by firstly classifying the fingerprints and then performing the search in the respective class. Jain et al. proposed a fingerprint classification algorithm based on a two-stage classifier, which uses a K-nearest neighbor classifier in its first stage. The fingerprint classification algorithm is based on the fingercode representation which is an encoding of fingerprints that has been demonstrated to be an effective fingerprint biometric scheme because of its ability to capture both local and global details in a fingerprint image. We enhance this approach by improving the efficiency of the K-nearest neighbor classifier for fingercode-based fingerprint classification. Our research firstly investigates the various fast search algorithms in vector quantization (VQ) and the potential application in fingerprint classification, and then proposes two efficient algorithms based on the pyramid-based search algorithms in VQ. Experimental results on DB1 of FVC 2004 demonstrate that our algorithms can outperform the full search algorithm and the original pyramid-based search algorithms in terms of computational efficiency without sacrificing accuracy.

  5. 78 FR 54970 - Cotton Futures Classification: Optional Classification Procedure

    Science.gov (United States)

    2013-09-09

    ... Service 7 CFR Part 27 [AMS-CN-13-0043] RIN 0581-AD33 Cotton Futures Classification: Optional Classification Procedure AGENCY: Agricultural Marketing Service, USDA. ACTION: Proposed rule. SUMMARY: The... optional cotton futures classification procedure--identified and known as ``registration'' by the U.S...

  6. 32 CFR 2700.22 - Classification guides.

    Science.gov (United States)

    2010-07-01

    ... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall... direct derivative classification, shall identify the information to be protected in specific and uniform...

  7. Biological therapeutics

    National Research Council Canada - National Science Library

    Greenstein, Ben; Brook, Daniel A

    2011-01-01

    This introductory textbook covers all the main categories of biological medicines, including vaccines, hormonal preparations, drugs for rheumatoid arthritis and other connective tissue diseases, drugs...

  8. Biogeographic classification of the Caspian Sea

    Science.gov (United States)

    Fendereski, F.; Vogt, M.; Payne, M. R.; Lachkar, Z.; Gruber, N.; Salmanmahiny, A.; Hosseini, S. A.

    2014-11-01

    Like other inland seas, the Caspian Sea (CS) has been influenced by climate change and anthropogenic disturbance during recent decades, yet the scientific understanding of this water body remains poor. In this study, an eco-geographical classification of the CS based on physical information derived from space and in situ data is developed and tested against a set of biological observations. We used a two-step classification procedure, consisting of (i) a data reduction with self-organizing maps (SOMs) and (ii) a synthesis of the most relevant features into a reduced number of marine ecoregions using the hierarchical agglomerative clustering (HAC) method. From an initial set of 12 potential physical variables, 6 independent variables were selected for the classification algorithm, i.e., sea surface temperature (SST), bathymetry, sea ice, seasonal variation of sea surface salinity (DSSS), total suspended matter (TSM) and its seasonal variation (DTSM). The classification results reveal a robust separation between the northern and the middle/southern basins as well as a separation of the shallow nearshore waters from those offshore. The observed patterns in ecoregions can be attributed to differences in climate and geochemical factors such as distance from river, water depth and currents. A comparison of the annual and monthly mean Chl a concentrations between the different ecoregions shows significant differences (one-way ANOVA, P qualitative evaluation of differences in community composition based on recorded presence-absence patterns of 25 different species of plankton, fish and benthic invertebrate also confirms the relevance of the ecoregions as proxies for habitats with common biological characteristics.

  9. IAEA Classification of Uranium Deposits

    International Nuclear Information System (INIS)

    Bruneton, Patrice

    2014-01-01

    Classifications of uranium deposits follow two general approaches, focusing on: • descriptive features such as the geotectonic position, the host rock type, the orebody morphology, …… : « geologic classification »; • or on genetic aspects: « genetic classification »

  10. Classification of Osteogenesis Imperfecta revisited

    NARCIS (Netherlands)

    van Dijk, F. S.; Pals, G.; van Rijn, R. R.; Nikkels, P. G. J.; Cobben, J. M.

    2010-01-01

    In 1979 Sillence proposed a classification of Osteogenesis Imperfecta (OI) in OI types I, II, III and IV. In 2004 and 2007 this classification was expanded with OI types V-VIII because of distinct clinical features and/or different causative gene mutations. We propose a revised classification of OI

  11. The future of general classification

    DEFF Research Database (Denmark)

    Mai, Jens Erik

    2013-01-01

    Discusses problems related to accessing multiple collections using a single retrieval language. Surveys the concepts of interoperability and switching language. Finds that mapping between more indexing languages always will be an approximation. Surveys the issues related to general classification...... and contrasts that to special classifications. Argues for the use of general classifications to provide access to collections nationally and internationally....

  12. Lie Group Classification of a Generalized Lane-Emden Type System in Two Dimensions

    Directory of Open Access Journals (Sweden)

    Motlatsi Molati

    2012-01-01

    Full Text Available The aim of this work is to perform a complete Lie symmetry classification of a generalized Lane-Emden type system in two dimensions which models many physical phenomena in biological and physical sciences. The classical approach of group classification is employed for classification. We show that several cases arise in classifying the arbitrary parameters, the forms of which include amongst others the power law nonlinearity, and exponential and quadratic forms.

  13. [Headache: classification and diagnosis].

    Science.gov (United States)

    Carbaat, P A T; Couturier, E G M

    2016-11-01

    There are many types of headache and, moreover, many people have different types of headache at the same time. Adequate treatment is possible only on the basis of the correct diagnosis. Technically and in terms of content the current diagnostics process for headache is based on the 'International Classification of Headache Disorders' (ICHD-3-beta) that was produced under the auspices of the International Headache Society. This classification is based on a distinction between primary and secondary headaches. The most common primary headache types are the tension type headache, migraine and the cluster headache. Application of uniform diagnostic concepts is essential to come to the most appropriate treatment of the various types of headache.

  14. Classification of hand eczema

    DEFF Research Database (Denmark)

    Agner, T; Aalto-Korte, K; Andersen, K E

    2015-01-01

    BACKGROUND: Classification of hand eczema (HE) is mandatory in epidemiological and clinical studies, and also important in clinical work. OBJECTIVES: The aim was to test a recently proposed classification system of HE in clinical practice in a prospective multicentre study. METHODS: Patients were...... recruited from nine different tertiary referral centres. All patients underwent examination by specialists in dermatology and were checked using relevant allergy testing. Patients were classified into one of the six diagnostic subgroups of HE: allergic contact dermatitis, irritant contact dermatitis, atopic...... system investigated in the present study was useful, being able to give an appropriate main diagnosis for 89% of HE patients, and for another 7% when using two main diagnoses. The fact that more than half of the patients had one or more additional diagnoses illustrates that HE is a multifactorial disease....

  15. Sound classification of dwellings

    DEFF Research Database (Denmark)

    Rasmussen, Birgit

    2012-01-01

    National schemes for sound classification of dwellings exist in more than ten countries in Europe, typically published as national standards. The schemes define quality classes reflecting different levels of acoustical comfort. Main criteria concern airborne and impact sound insulation between...... dwellings, facade sound insulation and installation noise. The schemes have been developed, implemented and revised gradually since the early 1990s. However, due to lack of coordination between countries, there are significant discrepancies, and new standards and revisions continue to increase the diversity...... is needed, and a European COST Action TU0901 "Integrating and Harmonizing Sound Insulation Aspects in Sustainable Urban Housing Constructions", has been established and runs 2009-2013, one of the main objectives being to prepare a proposal for a European sound classification scheme with a number of quality...

  16. Is synthetic biology mechanical biology?

    Science.gov (United States)

    Holm, Sune

    2015-12-01

    A widespread and influential characterization of synthetic biology emphasizes that synthetic biology is the application of engineering principles to living systems. Furthermore, there is a strong tendency to express the engineering approach to organisms in terms of what seems to be an ontological claim: organisms are machines. In the paper I investigate the ontological and heuristic significance of the machine analogy in synthetic biology. I argue that the use of the machine analogy and the aim of producing rationally designed organisms does not necessarily imply a commitment to mechanical biology. The ideal of applying engineering principles to biology is best understood as expressing recognition of the machine-unlikeness of natural organisms and the limits of human cognition. The paper suggests an interpretation of the identification of organisms with machines in synthetic biology according to which it expresses a strategy for representing, understanding, and constructing living systems that are more machine-like than natural organisms.

  17. Granular loess classification based

    International Nuclear Information System (INIS)

    Browzin, B.S.

    1985-01-01

    This paper discusses how loess might be identified by two index properties: the granulometric composition and the dry unit weight. These two indices are necessary but not always sufficient for identification of loess. On the basis of analyses of samples from three continents, it was concluded that the 0.01-0.5-mm fraction deserves the name loessial fraction. Based on the loessial fraction concept, a granulometric classification of loess is proposed. A triangular chart is used to classify loess

  18. Classification and regression trees

    CERN Document Server

    Breiman, Leo; Olshen, Richard A; Stone, Charles J

    1984-01-01

    The methodology used to construct tree structured rules is the focus of this monograph. Unlike many other statistical procedures, which moved from pencil and paper to calculators, this text's use of trees was unthinkable before computers. Both the practical and theoretical sides have been developed in the authors' study of tree methods. Classification and Regression Trees reflects these two sides, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.

  19. CLASSIFICATION OF CRIMINAL GROUPS

    OpenAIRE

    Natalia Romanova

    2013-01-01

    New types of criminal groups are emerging in modern society.  These types have their special criminal subculture. The research objective is to develop new parameters of classification of modern criminal groups, create a new typology of criminal groups and identify some features of their subculture. Research methodology is based on the system approach that includes using the method of analysis of documentary sources (materials of a criminal case), method of conversations with themembers of the...

  20. Decimal Classification Editions

    Directory of Open Access Journals (Sweden)

    Zenovia Niculescu

    2009-01-01

    Full Text Available The study approaches the evolution of Dewey Decimal Classification editions from the perspective of updating the terminology, reallocating and expanding the main and auxilary structure of Dewey indexing language. The comparative analysis of DDC editions emphasizes the efficiency of Dewey scheme from the point of view of improving the informational offer, through basic index terms, revised and developed, as well as valuing the auxilary notations.

  1. Decimal Classification Editions

    OpenAIRE

    Zenovia Niculescu

    2009-01-01

    The study approaches the evolution of Dewey Decimal Classification editions from the perspective of updating the terminology, reallocating and expanding the main and auxilary structure of Dewey indexing language. The comparative analysis of DDC editions emphasizes the efficiency of Dewey scheme from the point of view of improving the informational offer, through basic index terms, revised and developed, as well as valuing the auxilary notations.

  2. Computational biology

    DEFF Research Database (Denmark)

    Hartmann, Lars Røeboe; Jones, Neil; Simonsen, Jakob Grue

    2011-01-01

    Computation via biological devices has been the subject of close scrutiny since von Neumann’s early work some 60 years ago. In spite of the many relevant works in this field, the notion of programming biological devices seems to be, at best, ill-defined. While many devices are claimed or proved t...

  3. Mesoscopic biology

    Indian Academy of Sciences (India)

    In this paper we present a qualitative outlook of mesoscopic biology where the typical length scale is of the order of nanometers and the energy scales comparable to thermal energy. Novel biomolecular machines, governed by coded information at the level of DNA and proteins, operate at these length scales in biological ...

  4. Neuromuscular disease classification system

    Science.gov (United States)

    Sáez, Aurora; Acha, Begoña; Montero-Sánchez, Adoración; Rivas, Eloy; Escudero, Luis M.; Serrano, Carmen

    2013-06-01

    Diagnosis of neuromuscular diseases is based on subjective visual assessment of biopsies from patients by the pathologist specialist. A system for objective analysis and classification of muscular dystrophies and neurogenic atrophies through muscle biopsy images of fluorescence microscopy is presented. The procedure starts with an accurate segmentation of the muscle fibers using mathematical morphology and a watershed transform. A feature extraction step is carried out in two parts: 24 features that pathologists take into account to diagnose the diseases and 58 structural features that the human eye cannot see, based on the assumption that the biopsy is considered as a graph, where the nodes are represented by each fiber, and two nodes are connected if two fibers are adjacent. A feature selection using sequential forward selection and sequential backward selection methods, a classification using a Fuzzy ARTMAP neural network, and a study of grading the severity are performed on these two sets of features. A database consisting of 91 images was used: 71 images for the training step and 20 as the test. A classification error of 0% was obtained. It is concluded that the addition of features undetectable by the human visual inspection improves the categorization of atrophic patterns.

  5. An automated cirrus classification

    Science.gov (United States)

    Gryspeerdt, Edward; Quaas, Johannes; Goren, Tom; Klocke, Daniel; Brueck, Matthias

    2018-05-01

    Cirrus clouds play an important role in determining the radiation budget of the earth, but many of their properties remain uncertain, particularly their response to aerosol variations and to warming. Part of the reason for this uncertainty is the dependence of cirrus cloud properties on the cloud formation mechanism, which itself is strongly dependent on the local meteorological conditions. In this work, a classification system (Identification and Classification of Cirrus or IC-CIR) is introduced to identify cirrus clouds by the cloud formation mechanism. Using reanalysis and satellite data, cirrus clouds are separated into four main types: orographic, frontal, convective and synoptic. Through a comparison to convection-permitting model simulations and back-trajectory-based analysis, it is shown that these observation-based regimes can provide extra information on the cloud-scale updraughts and the frequency of occurrence of liquid-origin ice, with the convective regime having higher updraughts and a greater occurrence of liquid-origin ice compared to the synoptic regimes. Despite having different cloud formation mechanisms, the radiative properties of the regimes are not distinct, indicating that retrieved cloud properties alone are insufficient to completely describe them. This classification is designed to be easily implemented in GCMs, helping improve future model-observation comparisons and leading to improved parametrisations of cirrus cloud processes.

  6. Signal classification using global dynamical models, Part I: Theory

    International Nuclear Information System (INIS)

    Kadtke, J.; Kremliovsky, M.

    1996-01-01

    Detection and classification of signals is one of the principal areas of signal processing, and the utilization of nonlinear information has long been considered as a way of improving performance beyond standard linear (e.g. spectral) techniques. Here, we develop a method for using global models of chaotic dynamical systems theory to define a signal classification processing chain, which is sensitive to nonlinear correlations in the data. We use it to demonstrate classification in high noise regimes (negative SNR), and argue that classification probabilities can be directly computed from ensemble statistics in the model coefficient space. We also develop a modification for non-stationary signals (i.e. transients) using non-autonomous ODEs. In Part II of this paper, we demonstrate the analysis on actual open ocean acoustic data from marine biologics. copyright 1996 American Institute of Physics

  7. Automatic Classification Using Supervised Learning in a Medical Document Filtering Application.

    Science.gov (United States)

    Mostafa, J.; Lam, W.

    2000-01-01

    Presents a multilevel model of the information filtering process that permits document classification. Evaluates a document classification approach based on a supervised learning algorithm, measures the accuracy of the algorithm in a neural network that was trained to classify medical documents on cell biology, and discusses filtering…

  8. Systema naturae or the outline of living world classification

    OpenAIRE

    Shipunov, Alexey

    2009-01-01

    Here we present the short outline of the classification of living things (to the level of classes), given with two main goals: to provide a compact, synthetic overview of the biological diversity; and to supply users with up-todate information of latest taxonomic achievements. The latter is especially important in the recent epoch of molecular revolution in the taxonomy.

  9. Classification of mitocans, anti-cancer drugs acting on mitochondria

    Czech Academy of Sciences Publication Activity Database

    Neužil, Jiří; Dong, L. F.; Rohlena, Jakub; Truksa, Jaroslav; Ralph, S. J.

    2013-01-01

    Roč. 13, č. 3 (2013), s. 199-208 ISSN 1567-7249 Institutional research plan: CEZ:AV0Z50520701 Keywords : Mitocans * Anti-cancer therapeutics * Classification Subject RIV: EB - Gene tics ; Molecular Biology Impact factor: 3.524, year: 2013

  10. Classification of mitocans, anti-cancer drugs acting on mitochondria

    Czech Academy of Sciences Publication Activity Database

    Neužil, Jiří; Dong, L. F.; Rohlena, Jakub; Truksa, Jaroslav; Ralph, S. J.

    2013-01-01

    Roč. 13, č. 3 (2013), s. 199-208 ISSN 1567-7249 Institutional research plan: CEZ:AV0Z50520701 Keywords : Mitocans * Anti-cancer therapeutics * Classification Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.524, year: 2013

  11. Automatic workflow for the classification of local DNA conformations

    Czech Academy of Sciences Publication Activity Database

    Čech, P.; Kukal, J.; Černý, Jiří; Schneider, Bohdan; Svozil, D.

    2013-01-01

    Roč. 14, č. 205 (2013) ISSN 1471-2105 R&D Projects: GA ČR GAP305/12/1801 Institutional research plan: CEZ:AV0Z50520701 Keywords : DNA * Dinucleotide conformation * Classification * Machine learning * Neural network * k-NN * Cluster analysis Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.672, year: 2013

  12. Deep learning for tumor classification in imaging mass spectrometry.

    Science.gov (United States)

    Behrmann, Jens; Etmann, Christian; Boskamp, Tobias; Casadonte, Rita; Kriegsmann, Jörg; Maaß, Peter

    2018-04-01

    Tumor classification using imaging mass spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are required to fully process the data. Since mass spectra exhibit certain structural similarities to image data, deep learning may offer a promising strategy for classification of IMS data as it has been successfully applied to image classification. Methodologically, we propose an adapted architecture based on deep convolutional networks to handle the characteristics of mass spectrometry data, as well as a strategy to interpret the learned model in the spectral domain based on a sensitivity analysis. The proposed methods are evaluated on two algorithmically challenging tumor classification tasks and compared to a baseline approach. Competitiveness of the proposed methods is shown on both tasks by studying the performance via cross-validation. Moreover, the learned models are analyzed by the proposed sensitivity analysis revealing biologically plausible effects as well as confounding factors of the considered tasks. Thus, this study may serve as a starting point for further development of deep learning approaches in IMS classification tasks. https://gitlab.informatik.uni-bremen.de/digipath/Deep_Learning_for_Tumor_Classification_in_IMS. jbehrmann@uni-bremen.de or christianetmann@uni-bremen.de. Supplementary data are available at Bioinformatics online.

  13. Lauren classification and individualized chemotherapy in gastric cancer.

    Science.gov (United States)

    Ma, Junli; Shen, Hong; Kapesa, Linda; Zeng, Shan

    2016-05-01

    Gastric cancer is one of the most common malignancies worldwide. During the last 50 years, the histological classification of gastric carcinoma has been largely based on Lauren's criteria, in which gastric cancer is classified into two major histological subtypes, namely intestinal type and diffuse type adenocarcinoma. This classification was introduced in 1965, and remains currently widely accepted and employed, since it constitutes a simple and robust classification approach. The two histological subtypes of gastric cancer proposed by the Lauren classification exhibit a number of distinct clinical and molecular characteristics, including histogenesis, cell differentiation, epidemiology, etiology, carcinogenesis, biological behaviors and prognosis. Gastric cancer exhibits varied sensitivity to chemotherapy drugs and significant heterogeneity; therefore, the disease may be a target for individualized therapy. The Lauren classification may provide the basis for individualized treatment for advanced gastric cancer, which is increasingly gaining attention in the scientific field. However, few studies have investigated individualized treatment that is guided by pathological classification. The aim of the current review is to analyze the two major histological subtypes of gastric cancer, as proposed by the Lauren classification, and to discuss the implications of this for personalized chemotherapy.

  14. Maximum mutual information regularized classification

    KAUST Repository

    Wang, Jim Jing-Yan

    2014-09-07

    In this paper, a novel pattern classification approach is proposed by regularizing the classifier learning to maximize mutual information between the classification response and the true class label. We argue that, with the learned classifier, the uncertainty of the true class label of a data sample should be reduced by knowing its classification response as much as possible. The reduced uncertainty is measured by the mutual information between the classification response and the true class label. To this end, when learning a linear classifier, we propose to maximize the mutual information between classification responses and true class labels of training samples, besides minimizing the classification error and reducing the classifier complexity. An objective function is constructed by modeling mutual information with entropy estimation, and it is optimized by a gradient descend method in an iterative algorithm. Experiments on two real world pattern classification problems show the significant improvements achieved by maximum mutual information regularization.

  15. Maximum mutual information regularized classification

    KAUST Repository

    Wang, Jim Jing-Yan; Wang, Yi; Zhao, Shiguang; Gao, Xin

    2014-01-01

    In this paper, a novel pattern classification approach is proposed by regularizing the classifier learning to maximize mutual information between the classification response and the true class label. We argue that, with the learned classifier, the uncertainty of the true class label of a data sample should be reduced by knowing its classification response as much as possible. The reduced uncertainty is measured by the mutual information between the classification response and the true class label. To this end, when learning a linear classifier, we propose to maximize the mutual information between classification responses and true class labels of training samples, besides minimizing the classification error and reducing the classifier complexity. An objective function is constructed by modeling mutual information with entropy estimation, and it is optimized by a gradient descend method in an iterative algorithm. Experiments on two real world pattern classification problems show the significant improvements achieved by maximum mutual information regularization.

  16. American College of Rheumatology classification criteria for Sjögren's syndrome

    DEFF Research Database (Denmark)

    Shiboski, S C; Shiboski, C H; Criswell, L A

    2012-01-01

    We propose new classification criteria for Sjögren's syndrome (SS), which are needed considering the emergence of biologic agents as potential treatments and their associated comorbidity. These criteria target individuals with signs/symptoms suggestive of SS.......We propose new classification criteria for Sjögren's syndrome (SS), which are needed considering the emergence of biologic agents as potential treatments and their associated comorbidity. These criteria target individuals with signs/symptoms suggestive of SS....

  17. Quantum Biology

    Directory of Open Access Journals (Sweden)

    Alessandro Sergi

    2009-06-01

    Full Text Available A critical assessment of the recent developmentsof molecular biology is presented.The thesis that they do not lead to a conceptualunderstanding of life and biological systems is defended.Maturana and Varela's concept of autopoiesis is briefly sketchedand its logical circularity avoided by postulatingthe existence of underlying living processes,entailing amplification from the microscopic to the macroscopic scale,with increasing complexity in the passage from one scale to the other.Following such a line of thought, the currently accepted model of condensed matter, which is based on electrostatics and short-ranged forces,is criticized. It is suggested that the correct interpretationof quantum dispersion forces (van der Waals, hydrogen bonding, and so onas quantum coherence effects hints at the necessity of includinglong-ranged forces (or mechanisms for them incondensed matter theories of biological processes.Some quantum effects in biology are reviewedand quantum mechanics is acknowledged as conceptually important to biology since withoutit most (if not all of the biological structuresand signalling processes would not even exist. Moreover, it is suggested that long-rangequantum coherent dynamics, including electron polarization,may be invoked to explain signal amplificationprocess in biological systems in general.

  18. Using the biological literature a practical guide

    CERN Document Server

    Schmidt, Diane

    2014-01-01

    IntroductionSearching the Biological LiteratureGeneral SourcesAssociationsBibliographiesClassification, Nomenclature, and SystematicsDictionaries and EncyclopediasDirectoriesField GuidesSeriesFull-Text SourcesGeneral WorksGuides for young ScientistsGuides to the LiteratureHandbooksHistoriesMathematics and StatisticsMethods and TechniquesTextbooks and TreatisesWriting GuidesPeriodicalsReviews of the LiteratureAbstracts and IndexesBiochemistry and BiophysicsMolecular and Cellular BiologyGenetics, Biotechnology, and Developmental BiologyMicrobiology and ImmunologyEcology, Evolution, and Animal BehaviorPlant BiologyAnatomy and PhysiologyEntomologyZoologyIndex.

  19. Biological desulfurisation

    Energy Technology Data Exchange (ETDEWEB)

    Arena, B.J. [UOP LLC (United States); Benschop, A.; Janssen, A. [Paques Natural Solutions (Netherlands); Kijlstra, S. [Shell Global Solutions (Netherlands)

    2001-03-01

    This article focuses on the biological THIOPAQ process for removing hydrogen sulphide from refinery gases and recovering elemental sulphur. Details are given of the process which absorbs hydrogen sulphide-containing gas in alkaline solution prior to oxidation of the dissolved sulphur to elemental sulphur in a THIOPAQ aerobic biological reactor, with regeneration of the caustic solution. Sulphur handling options including sulphur wash, the drying of the sulphur cake, and sulphur smelting by pressure liquefaction are described. Agricultural applications of the biologically recovered sulphur, and application of the THIOPAQ process to sulphur recovery are discussed.

  20. Systems Biology

    Indian Academy of Sciences (India)

    IAS Admin

    study and understand the function of biological systems, particu- larly, the response of such .... understand the organisation and behaviour of prokaryotic sys- tems. ... relationship of the structure of a target molecule to its ability to bind a certain ...

  1. Classification of IRAS asteroids

    International Nuclear Information System (INIS)

    Tedesco, E.F.; Matson, D.L.; Veeder, G.J.

    1989-01-01

    Albedos and spectral reflectances are essential for classifying asteroids. For example, classes E, M and P are indistinguishable without albedo data. Colorometric data are available for about 1000 asteroids but, prior to IRAS, albedo data was available for only about 200. IRAS broke this bottleneck by providing albedo data on nearly 2000 asteroids. Hence, excepting absolute magnitudes, the albedo and size are now the most common asteroid physical parameters known. In this chapter the authors present the results of analyses of IRAS-derived asteroid albedos, discuss their application to asteroid classification, and mention several studies which might be done to exploit further this data set

  2. Radioactive facilities classification criteria

    International Nuclear Information System (INIS)

    Briso C, H.A.; Riesle W, J.

    1992-01-01

    Appropriate classification of radioactive facilities into groups of comparable risk constitutes one of the problems faced by most Regulatory Bodies. Regarding the radiological risk, the main facts to be considered are the radioactive inventory and the processes to which these radionuclides are subjected. Normally, operations are ruled by strict safety procedures. Thus, the total activity of the radionuclides existing in a given facility is the varying feature that defines its risk. In order to rely on a quantitative criterion and, considering that the Annual Limits of Intake are widely accepted references, an index based on these limits, to support decisions related to radioactive facilities, is proposed. (author)

  3. Supply chain planning classification

    Science.gov (United States)

    Hvolby, Hans-Henrik; Trienekens, Jacques; Bonde, Hans

    2001-10-01

    Industry experience a need to shift in focus from internal production planning towards planning in the supply network. In this respect customer oriented thinking becomes almost a common good amongst companies in the supply network. An increase in the use of information technology is needed to enable companies to better tune their production planning with customers and suppliers. Information technology opportunities and supply chain planning systems facilitate companies to monitor and control their supplier network. In spite if these developments, most links in today's supply chains make individual plans, because the real demand information is not available throughout the chain. The current systems and processes of the supply chains are not designed to meet the requirements now placed upon them. For long term relationships with suppliers and customers, an integrated decision-making process is needed in order to obtain a satisfactory result for all parties. Especially when customized production and short lead-time is in focus. An effective value chain makes inventory available and visible among the value chain members, minimizes response time and optimizes total inventory value held throughout the chain. In this paper a supply chain planning classification grid is presented based current manufacturing classifications and supply chain planning initiatives.

  4. Waste classification sampling plan

    International Nuclear Information System (INIS)

    Landsman, S.D.

    1998-01-01

    The purpose of this sampling is to explain the method used to collect and analyze data necessary to verify and/or determine the radionuclide content of the B-Cell decontamination and decommissioning waste stream so that the correct waste classification for the waste stream can be made, and to collect samples for studies of decontamination methods that could be used to remove fixed contamination present on the waste. The scope of this plan is to establish the technical basis for collecting samples and compiling quantitative data on the radioactive constituents present in waste generated during deactivation activities in B-Cell. Sampling and radioisotopic analysis will be performed on the fixed layers of contamination present on structural material and internal surfaces of process piping and tanks. In addition, dose rate measurements on existing waste material will be performed to determine the fraction of dose rate attributable to both removable and fixed contamination. Samples will also be collected to support studies of decontamination methods that are effective in removing the fixed contamination present on the waste. Sampling performed under this plan will meet criteria established in BNF-2596, Data Quality Objectives for the B-Cell Waste Stream Classification Sampling, J. M. Barnett, May 1998

  5. Cluster Based Text Classification Model

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah; Wiil, Uffe Kock

    2011-01-01

    We propose a cluster based classification model for suspicious email detection and other text classification tasks. The text classification tasks comprise many training examples that require a complex classification model. Using clusters for classification makes the model simpler and increases...... the accuracy at the same time. The test example is classified using simpler and smaller model. The training examples in a particular cluster share the common vocabulary. At the time of clustering, we do not take into account the labels of the training examples. After the clusters have been created......, the classifier is trained on each cluster having reduced dimensionality and less number of examples. The experimental results show that the proposed model outperforms the existing classification models for the task of suspicious email detection and topic categorization on the Reuters-21578 and 20 Newsgroups...

  6. Classification of smooth Fano polytopes

    DEFF Research Database (Denmark)

    Øbro, Mikkel

    A simplicial lattice polytope containing the origin in the interior is called a smooth Fano polytope, if the vertices of every facet is a basis of the lattice. The study of smooth Fano polytopes is motivated by their connection to toric varieties. The thesis concerns the classification of smooth...... Fano polytopes up to isomorphism. A smooth Fano -polytope can have at most vertices. In case of vertices an explicit classification is known. The thesis contains the classification in case of vertices. Classifications of smooth Fano -polytopes for fixed exist only for . In the thesis an algorithm...... for the classification of smooth Fano -polytopes for any given is presented. The algorithm has been implemented and used to obtain the complete classification for ....

  7. Small-scale classification schemes

    DEFF Research Database (Denmark)

    Hertzum, Morten

    2004-01-01

    Small-scale classification schemes are used extensively in the coordination of cooperative work. This study investigates the creation and use of a classification scheme for handling the system requirements during the redevelopment of a nation-wide information system. This requirements...... classification inherited a lot of its structure from the existing system and rendered requirements that transcended the framework laid out by the existing system almost invisible. As a result, the requirements classification became a defining element of the requirements-engineering process, though its main...... effects remained largely implicit. The requirements classification contributed to constraining the requirements-engineering process by supporting the software engineers in maintaining some level of control over the process. This way, the requirements classification provided the software engineers...

  8. Active Learning for Text Classification

    OpenAIRE

    Hu, Rong

    2011-01-01

    Text classification approaches are used extensively to solve real-world challenges. The success or failure of text classification systems hangs on the datasets used to train them, without a good dataset it is impossible to build a quality system. This thesis examines the applicability of active learning in text classification for the rapid and economical creation of labelled training data. Four main contributions are made in this thesis. First, we present two novel selection strategies to cho...

  9. Unsupervised Classification Using Immune Algorithm

    OpenAIRE

    Al-Muallim, M. T.; El-Kouatly, R.

    2012-01-01

    Unsupervised classification algorithm based on clonal selection principle named Unsupervised Clonal Selection Classification (UCSC) is proposed in this paper. The new proposed algorithm is data driven and self-adaptive, it adjusts its parameters to the data to make the classification operation as fast as possible. The performance of UCSC is evaluated by comparing it with the well known K-means algorithm using several artificial and real-life data sets. The experiments show that the proposed U...

  10. [Definition, etiology, classification and presentation forms].

    Science.gov (United States)

    Mas Garriga, Xavier

    2014-01-01

    Osteoarthritis is defined as a degenerative process affecting the joints as a result of mechanical and biological disorders that destabilize the balance between the synthesis and degradation of joint cartilage, stimulating the growth of subchondral bone; chronic synovitis is also present. Currently, the joint is considered as a functional unit that includes distinct tissues, mainly cartilage, the synovial membrane, and subchondral bone, all of which are involved in the pathogenesis of the disease. Distinct risk factors for the development of osteoarthritis have been described: general, unmodifiable risk factors (age, sex, and genetic makeup), general, modifiable risk factors (obesity and hormonal factors) and local risk factors (prior joint anomalies and joint overload). Notable among the main factors related to disease progression are joint alignment defects and generalized osteoarthritis. Several classifications of osteoarthritis have been proposed but none is particularly important for the primary care management of the disease. These classifications include etiological (primary or idiopathic forms and secondary forms) and topographical (typical and atypical localizations) classifications, the Kellgren and Lawrence classification (radiological repercussions) and that of the American College of Rheumatology for osteoarthritis of the hand, hip and knee. The prevalence of knee osteoarthritis is 10.2% in Spain and shows a marked discrepancy between clinical and radiological findings. Hand osteoarthritis, with a prevalence of symptomatic involvement of around 6.2%, has several forms of presentation (nodal osteoarthritis, generalized osteoarthritis, rhizarthrosis, and erosive osteoarthritis). Symptomatic osteoarthritis of the hip affects between 3.5% and 5.6% of persons older than 50 years and has different radiological patterns depending on femoral head migration. Copyright © 2014 Elsevier España, S.L. All rights reserved.

  11. Reliability of Oronasal Fistula Classification.

    Science.gov (United States)

    Sitzman, Thomas J; Allori, Alexander C; Matic, Damir B; Beals, Stephen P; Fisher, David M; Samson, Thomas D; Marcus, Jeffrey R; Tse, Raymond W

    2018-01-01

    Objective Oronasal fistula is an important complication of cleft palate repair that is frequently used to evaluate surgical quality, yet reliability of fistula classification has never been examined. The objective of this study was to determine the reliability of oronasal fistula classification both within individual surgeons and between multiple surgeons. Design Using intraoral photographs of children with repaired cleft palate, surgeons rated the location of palatal fistulae using the Pittsburgh Fistula Classification System. Intrarater and interrater reliability scores were calculated for each region of the palate. Participants Eight cleft surgeons rated photographs obtained from 29 children. Results Within individual surgeons reliability for each region of the Pittsburgh classification ranged from moderate to almost perfect (κ = .60-.96). By contrast, reliability between surgeons was lower, ranging from fair to substantial (κ = .23-.70). Between-surgeon reliability was lowest for the junction of the soft and hard palates (κ = .23). Within-surgeon and between-surgeon reliability were almost perfect for the more general classification of fistula in the secondary palate (κ = .95 and κ = .83, respectively). Conclusions This is the first reliability study of fistula classification. We show that the Pittsburgh Fistula Classification System is reliable when used by an individual surgeon, but less reliable when used among multiple surgeons. Comparisons of fistula occurrence among surgeons may be subject to less bias if they use the more general classification of "presence or absence of fistula of the secondary palate" rather than the Pittsburgh Fistula Classification System.

  12. Holocaust With(out Bullets: The Public and Property of the Jewish People from Šabac and the Kladovo Transport 1941–1944

    Directory of Open Access Journals (Sweden)

    Sanja Petrović Todosijević

    2017-09-01

    Full Text Available This paper attempts to illustrate the role the municipal authorities in Šabac, which were headed by wartime mayor Branko Petrović, and which were part of Milan Aćimović’s collaborationist administration and Milan Nedić’s government, played in the process of usurping the right to property of the Jewish people from Šabac and from the Kladovo Transport, initially through the Committee for Registration and Evaluation of Jewish Property, and later through the Commissariat for Jewish Property.   Article received: May 2, 2017; Article accepted: May 8, 2017; Published online: September 15, 2017 Original scholarly paper How to cite this article: Petrović Todosijević, Sanja. "Holocaust With(out Bullets: The Public and Property of the Jewish People from Šabac and the Kladovo Transport 1941–1944." AM Journal of Art and Media Studies 13 (2017: 5-15. doi: 10.25038/am.v0i13.181

  13. Methods for data classification

    Science.gov (United States)

    Garrity, George [Okemos, MI; Lilburn, Timothy G [Front Royal, VA

    2011-10-11

    The present invention provides methods for classifying data and uncovering and correcting annotation errors. In particular, the present invention provides a self-organizing, self-correcting algorithm for use in classifying data. Additionally, the present invention provides a method for classifying biological taxa.

  14. Cancer classification in the genomic era: five contemporary problems.

    Science.gov (United States)

    Song, Qingxuan; Merajver, Sofia D; Li, Jun Z

    2015-10-19

    Classification is an everyday instinct as well as a full-fledged scientific discipline. Throughout the history of medicine, disease classification is central to how we develop knowledge, make diagnosis, and assign treatment. Here, we discuss the classification of cancer and the process of categorizing cancer subtypes based on their observed clinical and biological features. Traditionally, cancer nomenclature is primarily based on organ location, e.g., "lung cancer" designates a tumor originating in lung structures. Within each organ-specific major type, finer subgroups can be defined based on patient age, cell type, histological grades, and sometimes molecular markers, e.g., hormonal receptor status in breast cancer or microsatellite instability in colorectal cancer. In the past 15+ years, high-throughput technologies have generated rich new data regarding somatic variations in DNA, RNA, protein, or epigenomic features for many cancers. These data, collected for increasingly large tumor cohorts, have provided not only new insights into the biological diversity of human cancers but also exciting opportunities to discover previously unrecognized cancer subtypes. Meanwhile, the unprecedented volume and complexity of these data pose significant challenges for biostatisticians, cancer biologists, and clinicians alike. Here, we review five related issues that represent contemporary problems in cancer taxonomy and interpretation. (1) How many cancer subtypes are there? (2) How can we evaluate the robustness of a new classification system? (3) How are classification systems affected by intratumor heterogeneity and tumor evolution? (4) How should we interpret cancer subtypes? (5) Can multiple classification systems co-exist? While related issues have existed for a long time, we will focus on those aspects that have been magnified by the recent influx of complex multi-omics data. Exploration of these problems is essential for data-driven refinement of cancer classification

  15. [Biological agents].

    Science.gov (United States)

    Amano, Koichi

    2009-03-01

    There are two types of biological agents for the treatment of rheumatoid arthritis (RA); monoclonal antibodies and recombinant proteins. Among the latter, etanercept, a recombinant fusion protein of soluble TNF receptor and IgG was approved in 2005 in Japan. The post-marketing surveillance of 13,894 RA patients revealed the efficacy and safety profiles of etanercept in the Japanese population, as well as overseas studies. Abatacept, a recombinant fusion protein of CTLA4 and IgG, is another biological agent for RA. Two clinical trials disclosed the efficacy of abatacept for difficult-to-treat patients: the AIM for MTX-resistant cases and the ATTAIN for patients who are resistant to anti-TNF. The ATTEST trial suggested abatacept might have more acceptable safety profile than infliximab. These biologics are also promising for the treatment of RA for not only relieving clinical symptoms and signs but retarding structural damage.

  16. Biological preconcentrator

    Science.gov (United States)

    Manginell, Ronald P [Albuquerque, NM; Bunker, Bruce C [Albuquerque, NM; Huber, Dale L [Albuquerque, NM

    2008-09-09

    A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

  17. Radiation biology in Canada 1962-63

    International Nuclear Information System (INIS)

    Thacker, D.G.

    1963-02-01

    A survey of the research projects in radiation biology being carried out in Canada during the fiscal year 1962-63. The report includes the names of the investigators, their location, a brief description of the projects and information on the financial support being provided. A classification of the projects into areas of specific interest is also included. (author)

  18. Systems Biology of Glucocorticoids in Muscle Disease

    Science.gov (United States)

    2010-10-01

    Introduction Duchenne muscular dystrophy (DMD) is the most common and incurable muscular dystrophy of childhood. Muscle regeneration fails with...SUBJECT TERMS Duchenne Muscular dystrophy , Glucocorticoids, Systems biology, Drug mechanism 16. SECURITY CLASSIFICATION OF: U 17. LIMITATION...better targeted and more effective therapies for Duchenne muscular dystrophy dynamically. This MDA grant proposal is led by Dr. Eric Hoffman, and it

  19. Barrett's esophagus: cancer and molecular biology

    NARCIS (Netherlands)

    Gibson, Michael K.; Dhaliwal, Arashinder S.; Clemons, Nicholas J.; Phillips, Wayne A.; Dvorak, Katerina; Tong, Daniel; Law, Simon; Pirchi, E. Daniel; Räsänen, Jari; Krasna, Mark J.; Parikh, Kaushal; Krishnadath, Kausilia K.; Chen, Yu; Griffiths, Leonard; Colleypriest, Benjamin J.; Farrant, J. Mark; Tosh, David; Das, Kiron M.; Bajpai, Manisha

    2013-01-01

    The following paper on the molecular biology of Barrett's esophagus (BE) includes commentaries on signaling pathways central to the development of BE including Hh, NF-κB, and IL-6/STAT3; surgical approaches for esophagectomy and classification of lesions by appropriate therapy; the debate over the

  20. Simple Calculation Programs for Biology Other Methods

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Simple Calculation Programs for Biology Other Methods. Hemolytic potency of drugs. Raghava et al., (1994) Biotechniques 17: 1148. FPMAP: methods for classification and identification of microorganisms 16SrRNA. graphical display of restriction and fragment map of ...

  1. Probing spermiogenesis: a digital strategy for mouse acrosome classification.

    Science.gov (United States)

    Taloni, Alessandro; Font-Clos, Francesc; Guidetti, Luca; Milan, Simone; Ascagni, Miriam; Vasco, Chiara; Pasini, Maria Enrica; Gioria, Maria Rosa; Ciusani, Emilio; Zapperi, Stefano; La Porta, Caterina A M

    2017-06-16

    Classification of morphological features in biological samples is usually performed by a trained eye but the increasing amount of available digital images calls for semi-automatic classification techniques. Here we explore this possibility in the context of acrosome morphological analysis during spermiogenesis. Our method combines feature extraction from three dimensional reconstruction of confocal images with principal component analysis and machine learning. The method could be particularly useful in cases where the amount of data does not allow for a direct inspection by trained eye.

  2. Multispectral Image classification using the theories of neural networks

    International Nuclear Information System (INIS)

    Ardisasmita, M.S.; Subki, M.I.R.

    1997-01-01

    Image classification is the one of the important part of digital image analysis. the objective of image classification is to identify and regroup the features occurring in an image into one or several classes in terms of the object. basic to the understanding of multispectral classification is the concept of the spectral response of an object as a function of the electromagnetic radiation and the wavelength of the spectrum. new approaches to classification has been developed to improve the result of analysis, these state-of-the-art classifiers are based upon the theories of neural networks. Neural network classifiers are algorithmes which mimic the computational abilities of the human brain. Artificial neurons are simple emulation's of biological neurons; they take in information from sensors or other artificial neurons, perform very simple operations on this data, and pass the result to other recognize the spectral signature of each image pixel. Neural network image classification has been divided into supervised and unsupervised training procedures. In the supervised approach, examples of each cover type can be located and the computer can compute spectral signatures to categorize all pixels in a digital image into several land cover classes. In supervised classification, spectral signatures are generated by mathematically grouping and it does not require analyst-specified training data. Thus, in the supervised approach we define useful information categories and then examine their spectral reparability; in the unsupervised approach the computer determines spectrally sapable classes and then we define thei information value

  3. Classification of radioactive waste

    International Nuclear Information System (INIS)

    1994-01-01

    Radioactive wastes are generated in a number of different kinds of facilities and arise in a wide range of concentrations of radioactive materials and in a variety of physical and chemical forms. To simplify their management, a number of schemes have evolved for classifying radioactive waste according to the physical, chemical and radiological properties of significance to those facilities managing this waste. These schemes have led to a variety of terminologies, differing from country to country and even between facilities in the same country. This situation makes it difficult for those concerned to communicate with one another regarding waste management practices. This document revises and updates earlier IAEA references on radioactive waste classification systems given in IAEA Technical Reports Series and Safety Series. Guidance regarding exemption of materials from regulatory control is consistent with IAEA Safety Series and the RADWASS documents published under IAEA Safety Series. 11 refs, 2 figs, 2 tab

  4. Nonlinear estimation and classification

    CERN Document Server

    Hansen, Mark; Holmes, Christopher; Mallick, Bani; Yu, Bin

    2003-01-01

    Researchers in many disciplines face the formidable task of analyzing massive amounts of high-dimensional and highly-structured data This is due in part to recent advances in data collection and computing technologies As a result, fundamental statistical research is being undertaken in a variety of different fields Driven by the complexity of these new problems, and fueled by the explosion of available computer power, highly adaptive, non-linear procedures are now essential components of modern "data analysis," a term that we liberally interpret to include speech and pattern recognition, classification, data compression and signal processing The development of new, flexible methods combines advances from many sources, including approximation theory, numerical analysis, machine learning, signal processing and statistics The proposed workshop intends to bring together eminent experts from these fields in order to exchange ideas and forge directions for the future

  5. Automatic diabetic retinopathy classification

    Science.gov (United States)

    Bravo, María. A.; Arbeláez, Pablo A.

    2017-11-01

    Diabetic retinopathy (DR) is a disease in which the retina is damaged due to augmentation in the blood pressure of small vessels. DR is the major cause of blindness for diabetics. It has been shown that early diagnosis can play a major role in prevention of visual loss and blindness. This work proposes a computer based approach for the detection of DR in back-of-the-eye images based on the use of convolutional neural networks (CNNs). Our CNN uses deep architectures to classify Back-of-the-eye Retinal Photographs (BRP) in 5 stages of DR. Our method combines several preprocessing images of BRP to obtain an ACA score of 50.5%. Furthermore, we explore subproblems by training a larger CNN of our main classification task.

  6. Environmental biology

    International Nuclear Information System (INIS)

    Tschumi, P.A.

    1981-01-01

    Environmental biology illustrates the functioning of ecosystems and the dynamics of populations with many examples from limnology and terrestrial ecology. On this basis, present environmental problems are analyzed. The present environmental crisis is seen as a result of the failure to observe ecological laws. (orig.) [de

  7. Biological timekeeping

    DEFF Research Database (Denmark)

    Lloyd, David

    2016-01-01

    , the networks that connect differenttime domains and the oscillations, rhythms and biological clocks that coordinate andsynchronise the complexity of the living state.“It is the pattern maintained by this homeostasis, which is the touchstone ofour personal identity. Our tissues change as we live: the food we...

  8. Scaffolded biology.

    Science.gov (United States)

    Minelli, Alessandro

    2016-09-01

    Descriptions and interpretations of the natural world are dominated by dichotomies such as organism vs. environment, nature vs. nurture, genetic vs. epigenetic, but in the last couple of decades strong dissatisfaction with those partitions has been repeatedly voiced and a number of alternative perspectives have been suggested, from perspectives such as Dawkins' extended phenotype, Turner's extended organism, Oyama's Developmental Systems Theory and Odling-Smee's niche construction theory. Last in time is the description of biological phenomena in terms of hybrids between an organism (scaffolded system) and a living or non-living scaffold, forming unit systems to study processes such as reproduction and development. As scaffold, eventually, we can define any resource used by the biological system, especially in development and reproduction, without incorporating it as happens in the case of resources fueling metabolism. Addressing biological systems as functionally scaffolded systems may help pointing to functional relationships that can impart temporal marking to the developmental process and thus explain its irreversibility; revisiting the boundary between development and metabolism and also regeneration phenomena, by suggesting a conceptual framework within which to investigate phenomena of regular hypermorphic regeneration such as characteristic of deer antlers; fixing a periodization of development in terms of the times at which a scaffolding relationship begins or is terminated; and promoting plant galls to legitimate study objects of developmental biology.

  9. Biological digestion

    International Nuclear Information System (INIS)

    Rosevear, A.

    1988-01-01

    This paper discusses the biological degradation of non-radioactive organic material occurring in radioactive wastes. The biochemical steps are often performed using microbes or isolated enzymes in combination with chemical steps and the aim is to oxidise the carbon, hydrogen, nitrogen and sulphur to their respective oxides. (U.K.)

  10. Marine Biology

    Science.gov (United States)

    Dewees, Christopher M.; Hooper, Jon K.

    1976-01-01

    A variety of informational material for a course in marine biology or oceanology at the secondary level is presented. Among the topics discussed are: food webs and pyramids, planktonic blooms, marine life, plankton nets, food chains, phytoplankton, zooplankton, larval plankton and filter feeders. (BT)

  11. Hazard classification or risk assessment

    DEFF Research Database (Denmark)

    Hass, Ulla

    2013-01-01

    The EU classification of substances for e.g. reproductive toxicants is hazard based and does not to address the risk suchsubstances may pose through normal, or extreme, use. Such hazard classification complies with the consumer's right to know. It is also an incentive to careful use and storage...

  12. Seismic texture classification. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Vinther, R.

    1997-12-31

    The seismic texture classification method, is a seismic attribute that can both recognize the general reflectivity styles and locate variations from these. The seismic texture classification performs a statistic analysis for the seismic section (or volume) aiming at describing the reflectivity. Based on a set of reference reflectivities the seismic textures are classified. The result of the seismic texture classification is a display of seismic texture categories showing both the styles of reflectivity from the reference set and interpolations and extrapolations from these. The display is interpreted as statistical variations in the seismic data. The seismic texture classification is applied to seismic sections and volumes from the Danish North Sea representing both horizontal stratifications and salt diapers. The attribute succeeded in recognizing both general structure of successions and variations from these. Also, the seismic texture classification is not only able to display variations in prospective areas (1-7 sec. TWT) but can also be applied to deep seismic sections. The seismic texture classification is tested on a deep reflection seismic section (13-18 sec. TWT) from the Baltic Sea. Applied to this section the seismic texture classification succeeded in locating the Moho, which could not be located using conventional interpretation tools. The seismic texture classification is a seismic attribute which can display general reflectivity styles and deviations from these and enhance variations not found by conventional interpretation tools. (LN)

  13. Efficient AUC optimization for classification

    NARCIS (Netherlands)

    Calders, T.; Jaroszewicz, S.; Kok, J.N.; Koronacki, J.; Lopez de Mantaras, R.; Matwin, S.; Mladenic, D.; Skowron, A.

    2007-01-01

    In this paper we show an efficient method for inducing classifiers that directly optimize the area under the ROC curve. Recently, AUC gained importance in the classification community as a mean to compare the performance of classifiers. Because most classification methods do not optimize this

  14. Dewey Decimal Classification: A Quagmire.

    Science.gov (United States)

    Gamaluddin, Ahmad Fouad

    1980-01-01

    A survey of 660 Pennsylvania school librarians indicates that, though there is limited professional interest in the Library of Congress Classification system, Dewey Decimal Classification (DDC) appears to be firmly entrenched. This article also discusses the relative merits of DDC, the need for a uniform system, librarianship preparation, and…

  15. Latent class models for classification

    NARCIS (Netherlands)

    Vermunt, J.K.; Magidson, J.

    2003-01-01

    An overview is provided of recent developments in the use of latent class (LC) and other types of finite mixture models for classification purposes. Several extensions of existing models are presented. Two basic types of LC models for classification are defined: supervised and unsupervised

  16. 45 CFR 601.5 - Derivative classification.

    Science.gov (United States)

    2010-10-01

    ... CLASSIFICATION AND DECLASSIFICATION OF NATIONAL SECURITY INFORMATION § 601.5 Derivative classification. Distinct... 45 Public Welfare 3 2010-10-01 2010-10-01 false Derivative classification. 601.5 Section 601.5... classification guide, need not possess original classification authority. (a) If a person who applies derivative...

  17. 12 CFR 403.4 - Derivative classification.

    Science.gov (United States)

    2010-01-01

    ... SAFEGUARDING OF NATIONAL SECURITY INFORMATION § 403.4 Derivative classification. (a) Use of derivative classification. (1) Unlike original classification which is an initial determination, derivative classification... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Derivative classification. 403.4 Section 403.4...

  18. 32 CFR 2001.15 - Classification guides.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Classification guides. 2001.15 Section 2001.15..., NATIONAL ARCHIVES AND RECORDS ADMINISTRATION CLASSIFIED NATIONAL SECURITY INFORMATION Classification § 2001.15 Classification guides. (a) Preparation of classification guides. Originators of classification...

  19. Vietnamese Document Representation and Classification

    Science.gov (United States)

    Nguyen, Giang-Son; Gao, Xiaoying; Andreae, Peter

    Vietnamese is very different from English and little research has been done on Vietnamese document classification, or indeed, on any kind of Vietnamese language processing, and only a few small corpora are available for research. We created a large Vietnamese text corpus with about 18000 documents, and manually classified them based on different criteria such as topics and styles, giving several classification tasks of different difficulty levels. This paper introduces a new syllable-based document representation at the morphological level of the language for efficient classification. We tested the representation on our corpus with different classification tasks using six classification algorithms and two feature selection techniques. Our experiments show that the new representation is effective for Vietnamese categorization, and suggest that best performance can be achieved using syllable-pair document representation, an SVM with a polynomial kernel as the learning algorithm, and using Information gain and an external dictionary for feature selection.

  20. A supervised learning rule for classification of spatiotemporal spike patterns.

    Science.gov (United States)

    Lilin Guo; Zhenzhong Wang; Adjouadi, Malek

    2016-08-01

    This study introduces a novel supervised algorithm for spiking neurons that take into consideration synapse delays and axonal delays associated with weights. It can be utilized for both classification and association and uses several biologically influenced properties, such as axonal and synaptic delays. This algorithm also takes into consideration spike-timing-dependent plasticity as in Remote Supervised Method (ReSuMe). This paper focuses on the classification aspect alone. Spiked neurons trained according to this proposed learning rule are capable of classifying different categories by the associated sequences of precisely timed spikes. Simulation results have shown that the proposed learning method greatly improves classification accuracy when compared to the Spike Pattern Association Neuron (SPAN) and the Tempotron learning rule.

  1. Biological radioprotector

    International Nuclear Information System (INIS)

    Stefanescu, Ioan; Titescu, Gheorghe; Tamaian, Radu; Haulica, Ion; Bild, Walther

    2002-01-01

    According to the patent description, the biological radioprotector is deuterium depleted water, DDW, produced by vacuum distillation with an isotopic content lower than natural value. It appears as such or in a mixture with natural water and carbon dioxide. It can be used for preventing and reducing the ionizing radiation effects upon humans or animal organisms, exposed therapeutically, professionally or accidentally to radiation. The most significant advantage of using DDW as biological radioprotector results from its way of administration. Indeed no one of the radioprotectors currently used today can be orally administrated, what reduces the patients' compliance to prophylactic administrations. The biological radioprotector is an unnoxious product obtained from natural water, which can be administrated as food additive instead of drinking water. Dose modification factor is according to initial estimates around 1.9, what is a remarkable feature when one takes into account that the product is toxicity-free and side effect-free and can be administrated prophylactically as a food additive. A net radioprotective action of the deuterium depletion was evidenced experimentally in laboratory animals (rats) hydrated with DDW of 30 ppm D/(D+H) concentration as compared with normally hydrated control animals. Knowing the effects of irradiation and mechanisms of the acute radiation disease as well as the effects of administration of radiomimetic chemicals upon cellular lines of fast cell division, it appears that the effects of administrating DDW result from stimulation of the immunity system. In conclusion, the biological radioprotector DDW presents the following advantages: - it is obtained from natural products without toxicity; - it is easy to be administrated as a food additive, replacing the drinking water; - besides radioprotective effects, the product has also immunostimulative and antitumoral effects

  2. Classification of titanium dioxide

    International Nuclear Information System (INIS)

    Macias B, L.R.; Garcia C, R.M.; Maya M, M.E.; Ita T, A. De; Palacios G, J.

    2002-01-01

    In this work the X-ray diffraction (XRD), Scanning Electron Microscopy (Sem) and the X-ray Dispersive Energy Spectroscopy techniques are used with the purpose to achieve a complete identification of phases and mixture of phases of a crystalline material as titanium dioxide. The problem for solving consists of being able to distinguish a sample of titanium dioxide being different than a titanium dioxide pigment. A standard sample of titanium dioxide with NIST certificate is used, which indicates a purity of 99.74% for the TiO 2 . The following way is recommended to proceed: a)To make an analysis by means of X-ray diffraction technique to the sample of titanium dioxide pigment and on the standard of titanium dioxide waiting not find differences. b) To make a chemical analysis by the X-ray Dispersive Energy Spectroscopy via in a microscope, taking advantage of the high vacuum since it is oxygen which is analysed and if it is concluded that the aluminium oxide appears in a greater proportion to 1% it is established that is a titanium dioxide pigment, but if it is lesser then it will be only titanium dioxide. This type of analysis is an application of the nuclear techniques useful for the tariff classification of merchandise which is considered as of difficult recognition. (Author)

  3. Classification of new particles

    International Nuclear Information System (INIS)

    Karl, G.

    1976-01-01

    A classification of the new particles is proposed. Hadrons are constructed from quarks corresponding to several different representations of an SU 3 color group, with confined color. The new family of resonances, related to psi/J, is assigned to color-antisextet quarks Q. These new quarks Q do not form mixed mesons q-barQ with old antiquarks but can form mixed baryons Qqq. We speculate on the relation between color and mass. High-mass recurrences of the psi/J family are expected to have associated large changes in the cross section for electron-positron annihilation (ΔR > 4). A conjectured mass formula, which relates the masses of psi/J and ω, predicts the masses of possible recurrences of the psi/J particle. Other experimental implications at presently available energies are discussed, especially the necessity for an isovector partner for psi/J, and for pseudoscalar mesons at 1.8--2.2 GeV, some of which can decay into two photons

  4. Protostome classification activity

    OpenAIRE

    Biederman, Lori

    2017-01-01

    I wrote this activity to have students work through the defining characteristics of various protostomes that I cover in my Introduction to Biology course. For in class materials I remove the red box (upper right corner) and print slides 4-18, place them back-to-back and laminate them.  The students get a key (slides 2 & 3) and an organism sheet and they are to answer the questions for each organism based on the info provided.   After class a...

  5. Generalization of Rindler Potential at Cluster Scales in Randers-Finslerian Spacetime: a Possible Explanation of the Bullet Cluster 1E0657-558?

    Science.gov (United States)

    Chang, Zhe; Li, Ming-Hua; Lin, Hai-Nan; Li, Xin

    2012-12-01

    The data of the Bullet Cluster 1E0657-558 released on November 15, 2006 reveal that the strong and weak gravitational lensing convergence κ-map has an 8σ offset from the Σ-map. The observed Σ-map is a direct measurement of the surface mass density of the Intracluster medium (ICM) gas. It accounts for 83% of the averaged mass-fraction of the system. This suggests a modified gravity theory at large distances different from Newton's inverse-square gravitational law. In this paper, as a cluster scale generalization of Grumiller's modified gravity model (Phys. Rev. Lett.105 (2010) 211303), we present a gravity model with a generalized linear Rindler potential in Randers-Finslerian spacetime without invoking any dark matter. The galactic limit of the model is qualitatively consistent with the MOND and Grumiller's. It yields approximately the flatness of the rotational velocity profile at the radial distance of several kpcs and gives the velocity scales for spiral galaxies at which the curves become flattened. Plots of convergence κ for a galaxy cluster show that the peak of the gravitational potential has chances to lie on the outskirts of the baryonic mass center. Assuming an isotropic and isothermal ICM gas profile with temperature T = 14.8 keV (which is the center value given by observations), we obtain a good match between the dynamical mass MT of the main cluster given by collisionless Boltzmann equation and that given by the King β-model. We also consider a Randers+dark matter scenario and a Λ-CDM model with the NFW dark matter distribution profile. We find that a mass ratio η between dark matter and baryonic matter about 6 fails to reproduce the observed convergence κ-map for the isothermal temperature T taking the observational center value.

  6. Music classification with MPEG-7

    Science.gov (United States)

    Crysandt, Holger; Wellhausen, Jens

    2003-01-01

    Driven by increasing amount of music available electronically the need and possibility of automatic classification systems for music becomes more and more important. Currently most search engines for music are based on textual descriptions like artist or/and title. This paper presents a system for automatic music description, classification and visualization for a set of songs. The system is designed to extract significant features of a piece of music in order to find songs of similar genre or a similar sound characteristics. The description is done with the help of MPEG-7 only. The classification and visualization is done with the self organizing map algorithm.

  7. Systema Naturae. Classification of living things.

    OpenAIRE

    Alexey Shipunov

    2007-01-01

    Original classification of living organisms containing four kingdoms (Monera, Protista, Vegetabilia and Animalia), 60 phyla and 254 classes, is presented. The classification is based on latest available information.

  8. Structural Biology Fact Sheet

    Science.gov (United States)

    ... NIGMS NIGMS Home > Science Education > Structural Biology Structural Biology Tagline (Optional) Middle/Main Content Area PDF Version (688 KB) Other Fact Sheets What is structural biology? Structural biology is the study of how biological ...

  9. Classification for longevity potential: the use of novel biomarkers

    Directory of Open Access Journals (Sweden)

    Marian Beekman

    2016-10-01

    Full Text Available Background: In older people chronological age may not be the best predictor of residual lifespan and mortality, because with age the heterogeneity in health is increasing. Biomarkers for biological age and residual lifespan are being developed to predict disease and mortality better at an individual level than chronological age. In the current paper we aim to classify a group of older people into those with longevity potential or controls.Methods: In the Leiden Longevity Study participated 1671 offspring of nonagenarian siblings, as the group with longevity potential, and 744 similarly aged controls. Using known risk factors for cardiovascular disease, previously reported markers for human longevity and other physiological measures as predictors, classification models for longevity potential were constructed with multiple logistic regression of the offspring-control status.Results: The Framingham Risk Score is predictive for longevity potential (AUC = 64.7. Physiological parameters involved in immune responses and glucose, lipid and energy metabolism further improve the prediction performance for longevity potential (AUCmale = 71.4, AUCfemale = 68.7.Conclusion: Using the Framingham Risk Score, the classification of older people in groups with longevity potential and controls is moderate, but can be improved to a reasonably good classification in combination with markers of immune response, glucose, lipid and energy metabolism. We show that individual classification of older people for longevity potential may be feasible using biomarkers from a wide variety of different biological processes.

  10. A three-way approach for protein function classification.

    Directory of Open Access Journals (Sweden)

    Hafeez Ur Rehman

    Full Text Available The knowledge of protein functions plays an essential role in understanding biological cells and has a significant impact on human life in areas such as personalized medicine, better crops and improved therapeutic interventions. Due to expense and inherent difficulty of biological experiments, intelligent methods are generally relied upon for automatic assignment of functions to proteins. The technological advancements in the field of biology are improving our understanding of biological processes and are regularly resulting in new features and characteristics that better describe the role of proteins. It is inevitable to neglect and overlook these anticipated features in designing more effective classification techniques. A key issue in this context, that is not being sufficiently addressed, is how to build effective classification models and approaches for protein function prediction by incorporating and taking advantage from the ever evolving biological information. In this article, we propose a three-way decision making approach which provides provisions for seeking and incorporating future information. We considered probabilistic rough sets based models such as Game-Theoretic Rough Sets (GTRS and Information-Theoretic Rough Sets (ITRS for inducing three-way decisions. An architecture of protein functions classification with probabilistic rough sets based three-way decisions is proposed and explained. Experiments are carried out on Saccharomyces cerevisiae species dataset obtained from Uniprot database with the corresponding functional classes extracted from the Gene Ontology (GO database. The results indicate that as the level of biological information increases, the number of deferred cases are reduced while maintaining similar level of accuracy.

  11. Progression in nuclear classification

    International Nuclear Information System (INIS)

    Wang Yuying

    1999-01-01

    In this book, summarize the author's achievements of nuclear classification by new method in latest 30 years, new foundational law of nuclear layer in matter world is found. It is explained with a hypothesis of a nucleus which it is made up of two nucleon's clusters with deuteron and triton. Its concrete content is: to advance a new method which analyze data of nuclei with natural abundance using relationship between the numbers of proton and neutron. The relationship of each nucleus increases to 4 sets: S+H=Z H+Z=N Z+N=A and S-H=K. To expand the similarity between proton and neutron to the similarity among p,n, deuteron, triton, and He-5 clusters. According to the distribution law of same kind of nuclei, it obtains that the upper limits of stable region both should be '44s'. New foundational law of nuclear system is 1,2,4,8,16,8,4,2,1. In order to explain new law, a hypothesis which nucleus is made up of deuteron and triton is developing and nuclear field of whole number is built up. And it relates that unity of matter motion, which is the most foundational form atomic nuclear systematic is similar to the most first-class form chromosome numbers of mankind. These achievements will shake the foundations of traditional nuclear science. These achievements will supply new tasks in developing nuclear theory. And shake the ground of which magic number is the basic of nuclear science. It opens up a new field on foundational research. The book will supply new knowledge for researcher, teachers and students in universities and polytechnic schools. Scientific workers read in works of research and technical exploit. It can be stored up for library and laboratory of society and universities. In nowadays of prosperity our nation by science and education, the book is readable for workers of scientific technology and amateurs of natural science

  12. Classification and clinical assessment

    Directory of Open Access Journals (Sweden)

    F. Cantini

    2012-06-01

    Full Text Available There are at least nine classification criteria for psoriatic arthritis (PsA that have been proposed and used in clinical studies. With the exception of the ESSG and Bennett rules, all of the other criteria sets have a good performance in identifying PsA patients. As the CASPAR criteria are based on a robust study methodology, they are considered the current reference standard. However, if there seems to be no doubt that they are very good to classify PsA patients (very high specificity, they might be not sensitive enough to diagnose patients with unknown early PsA. The vast clinical heterogeneity of PsA makes its assessment very challenging. Peripheral joint involvement is measured by 78/76 joint counts, spine involvement by the instruments used for ankylosing spondylitis (AS, dactylitis by involved digit count or by the Leeds dactylitis index, enthesitis by the number of affected entheses (several indices available and psoriasis by the Psoriasis Area and Severity Index (PASI. Peripheral joint damage can be assessed by a modified van der Heijde-Sharp scoring system and axial damage by the methods used for AS or by the Psoriatic Arthritis Spondylitis Radiology Index (PASRI. As in other arthritides, global evaluation of disease activity and severity by patient and physician and assessment of disability and quality of life are widely used. Finally, composite indices that capture several clinical manifestations of PsA have been proposed and a new instrument, the Psoriatic ARthritis Disease Activity Score (PASDAS, is currently being developed.

  13. The classification of easement

    Directory of Open Access Journals (Sweden)

    Popov Danica D.

    2015-01-01

    Full Text Available Easement means, a right enjoyed by the owner of land over the lands of another: such as rights of way, right of light, rights of support, rights to a flow of air or water etc. The dominant tenement is the land owned by the possessor of the easement, and the servient tenement is the land over which the right is enjoyed. An easement must exist for the accommodation and better enjoyment to which it is annexed, otherwise it may amount to mere licence. An easement benefits and binds the land itself and therefore countinious despite any change of ownership of either dominant or servient tenement, although it will be extinguished if the two tenemants come into common ownership. An easement can only be enjoyed in respect of land. This means two parcels of land. First there must be a 'dominant tenement' and a 'servient tenement'. Dominant tenement to which the benefit of the easement attaches, and another (servient tenement which bears the burden of the easement. A positive easement consist of a right to do something on the land of another; a negative easement restrict the use of owner of the serviant tenement may make of his land. An easement may be on land or on the house made on land. The next classification is on easement on the ground, and the other one under the ground. An easement shall be done in accordance with the principle of restrictions. This means that the less burden the servient tenement. When there is doubt about the extent of the actual easement shall take what easier the servient tenement. The new needs of the dominant estate does not result in the expansion of servitude. In the article is made comparison between The Draft Code of property and other real estate, and The Draft of Civil Code of Serbia.

  14. Biology Branch

    Energy Technology Data Exchange (ETDEWEB)

    Baldwin, W F

    1974-12-31

    Progress is reported on the following studies in biochemistry and molecular biology: study of long pyrimidine polynucleotides in DNA; isolation of thymine dimers from Schizosaccharomyces pombe; thermal stability of high molecular weight RNA; nucleases of Micrococcus radiodurans; effect of ionizing radiation on M. radiodurans cell walls and cell membranes; chemical modification of nucleotides; exonucleases of M. radiodurans; and enzymatic basis of repair of radioinduced damage in M. radiodurans. Genetics, development, and population studies include repair pathways and mutation induction in yeast; induction of pure mutant clones in yeast; radiosensitivity of bacteriophage T4; polyacrylamide gel electrophoresis of bacteriophage T4; radiation genetics of Dahibominus; and radiation studies on bitting flies. (HLW)

  15. Critical Evaluation of Headache Classifications.

    Science.gov (United States)

    Özge, Aynur

    2013-08-01

    Transforming a subjective sense like headache into an objective state and establishing a common language for this complaint which can be both a symptom and a disease all by itself have kept the investigators busy for years. Each recommendation proposed has brought along a set of patients who do not meet the criteria. While almost the most ideal and most comprehensive classification studies continued at this point, this time criticisims about withdrawing from daily practice came to the fore. In this article, the classification adventure of scientists who work in the area of headache will be summarized. More specifically, 2 classifications made by the International Headache Society (IHS) and the point reached in relation with the 3rd classification which is still being worked on will be discussed together with headache subtypes. It has been presented with the wish and belief that it will contribute to the readers and young investigators who are interested in this subject.

  16. The last classification of vasculitis

    NARCIS (Netherlands)

    Kallenberg, Cees G. M.

    2008-01-01

    Systemic vasculitides are a group of diverse conditions characterized by inflammation of the blood vessels. To obtain homogeneity in clinical characteristics, prognosis, and response to treatment, patients with vasculitis should be classified into defined disease categories. Many classification

  17. Radon classification of building ground

    International Nuclear Information System (INIS)

    Slunga, E.

    1988-01-01

    The Laboratories of Building Technology and Soil Mechanics and Foundation Engineering at the Helsinki University of Technology in cooperation with The Ministry of the Environment have proposed a radon classification for building ground. The proposed classification is based on the radon concentration in soil pores and on the permeability of the foundation soil. The classification includes four radon classes: negligible, normal, high and very high. Depending on the radon class the radon-technical solution for structures is chosen. It is proposed that the classification be done in general terms in connection with the site investigations for the planning of land use and in more detail in connection with the site investigations for an individual house. (author)

  18. Deep Learning for ECG Classification

    Science.gov (United States)

    Pyakillya, B.; Kazachenko, N.; Mikhailovsky, N.

    2017-10-01

    The importance of ECG classification is very high now due to many current medical applications where this problem can be stated. Currently, there are many machine learning (ML) solutions which can be used for analyzing and classifying ECG data. However, the main disadvantages of these ML results is use of heuristic hand-crafted or engineered features with shallow feature learning architectures. The problem relies in the possibility not to find most appropriate features which will give high classification accuracy in this ECG problem. One of the proposing solution is to use deep learning architectures where first layers of convolutional neurons behave as feature extractors and in the end some fully-connected (FCN) layers are used for making final decision about ECG classes. In this work the deep learning architecture with 1D convolutional layers and FCN layers for ECG classification is presented and some classification results are showed.

  19. Vehicle classification using mobile sensors.

    Science.gov (United States)

    2013-04-01

    In this research, the feasibility of using mobile traffic sensors for binary vehicle classification on arterial roads is investigated. Features (e.g. : speed related, acceleration/deceleration related, etc.) are extracted from vehicle traces (passeng...

  20. Classification of remotely sensed images

    CSIR Research Space (South Africa)

    Dudeni, N

    2008-10-01

    Full Text Available For this research, the researchers examine various existing image classification algorithms with the aim of demonstrating how these algorithms can be applied to remote sensing images. These algorithms are broadly divided into supervised...

  1. Classification of Building Object Types

    DEFF Research Database (Denmark)

    Jørgensen, Kaj Asbjørn

    2011-01-01

    made. This is certainly the case in the Danish development. Based on the theories about these abstraction mechanisms, the basic principles for classification systems are presented and the observed misconceptions are analyses and explained. Furthermore, it is argued that the purpose of classification...... systems has changed and that new opportunities should be explored. Some proposals for new applications are presented and carefully aligned with IT opportunities. Especially, the use of building modelling will give new benefits and many of the traditional uses of classification systems will instead...... be managed by software applications and on the basis of building models. Classification systems with taxonomies of building object types have many application opportunities but can still be beneficial in data exchange between building construction partners. However, this will be performed by new methods...

  2. VT Biodiversity Project - Bedrock Classification

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This dataset is a five category, nine sub-category classification of the bedrock units appearing on the Centennial Geologic Map of Vermont. The...

  3. Classification of Cortical Brain Malformations

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2008-03-01

    Full Text Available Clinical, radiological, and genetic classifications of 113 cases of malformations of cortical development (MCD were evaluated at the Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands.

  4. Insights into the classification of small GTPases

    Directory of Open Access Journals (Sweden)

    Dominik Heider

    2010-05-01

    Full Text Available Dominik Heider1, Sascha Hauke3, Martin Pyka4, Daniel Kessler21Department of Bioinformatics, Center for Medical Biotechnology, 2Institute of Cell Biology (Cancer Research, University of Duisburg-Essen, Essen, Germany; 3Institute of Computer Science, University of Münster, Münster, Germany; 4Interdisciplinary Center for Clinical Research, University Hospital of Münster, Münster, GermanyAbstract: In this study we used a Random Forest-based approach for an assignment of small guanosine triphosphate proteins (GTPases to specific subgroups. Small GTPases represent an important functional group of proteins that serve as molecular switches in a wide range of fundamental cellular processes, including intracellular transport, movement and signaling events. These proteins have further gained a special emphasis in cancer research, because within the last decades a huge variety of small GTPases from different subgroups could be related to the development of all types of tumors. Using a random forest approach, we were able to identify the most important amino acid positions for the classification process within the small GTPases superfamily and its subgroups. These positions are in line with the results of earlier studies and have been shown to be the essential elements for the different functionalities of the GTPase families. Furthermore, we provide an accurate and reliable software tool (GTPasePred to identify potential novel GTPases and demonstrate its application to genome sequences.Keywords: cancer, machine learning, classification, Random Forests, proteins

  5. Phylogenetic classification of bony fishes.

    Science.gov (United States)

    Betancur-R, Ricardo; Wiley, Edward O; Arratia, Gloria; Acero, Arturo; Bailly, Nicolas; Miya, Masaki; Lecointre, Guillaume; Ortí, Guillermo

    2017-07-06

    Fish classifications, as those of most other taxonomic groups, are being transformed drastically as new molecular phylogenies provide support for natural groups that were unanticipated by previous studies. A brief review of the main criteria used by ichthyologists to define their classifications during the last 50 years, however, reveals slow progress towards using an explicit phylogenetic framework. Instead, the trend has been to rely, in varying degrees, on deep-rooted anatomical concepts and authority, often mixing taxa with explicit phylogenetic support with arbitrary groupings. Two leading sources in ichthyology frequently used for fish classifications (JS Nelson's volumes of Fishes of the World and W. Eschmeyer's Catalog of Fishes) fail to adopt a global phylogenetic framework despite much recent progress made towards the resolution of the fish Tree of Life. The first explicit phylogenetic classification of bony fishes was published in 2013, based on a comprehensive molecular phylogeny ( www.deepfin.org ). We here update the first version of that classification by incorporating the most recent phylogenetic results. The updated classification presented here is based on phylogenies inferred using molecular and genomic data for nearly 2000 fishes. A total of 72 orders (and 79 suborders) are recognized in this version, compared with 66 orders in version 1. The phylogeny resolves placement of 410 families, or ~80% of the total of 514 families of bony fishes currently recognized. The ordinal status of 30 percomorph families included in this study, however, remains uncertain (incertae sedis in the series Carangaria, Ovalentaria, or Eupercaria). Comments to support taxonomic decisions and comparisons with conflicting taxonomic groups proposed by others are presented. We also highlight cases were morphological support exist for the groups being classified. This version of the phylogenetic classification of bony fishes is substantially improved, providing resolution

  6. A classification of chinese culture

    OpenAIRE

    Fan, Y

    2000-01-01

    This paper presents a classification of Chinese Cultural Values (CCVs). Although there exist great differences between the Mainland China, Hong Kong and Taiwan, it is still possible to identify certain core cultural values that are shared by the Chinese people no matter where they live. Based on the original list by the Chinese Cultural Connection (1987), the paper creates a new list that contains 71 core values against 40 in the old. The implications and limitations of the classification are...

  7. Classification of pyodestructive pulmonary diseases

    International Nuclear Information System (INIS)

    Muromskij, Yu.A.; Semivolkov, V.I.; Shlenova, L.A.

    1993-01-01

    Classification of pyodestructive lungs diseases, thier complications and outcomes is proposed which makes it possible for physioians engaged in studying respiratory organs pathology to orient themselves in problems of diagnosis and treatment tactics. The above classification is developed on the basis of studying the disease anamnesis and its clinical process, as well as on the basis of roentgenological and morphological study results by more than 10000 patients

  8. Quantum computing for pattern classification

    OpenAIRE

    Schuld, Maria; Sinayskiy, Ilya; Petruccione, Francesco

    2014-01-01

    It is well known that for certain tasks, quantum computing outperforms classical computing. A growing number of contributions try to use this advantage in order to improve or extend classical machine learning algorithms by methods of quantum information theory. This paper gives a brief introduction into quantum machine learning using the example of pattern classification. We introduce a quantum pattern classification algorithm that draws on Trugenberger's proposal for measuring the Hamming di...

  9. Mathematical classification and clustering

    CERN Document Server

    Mirkin, Boris

    1996-01-01

    I am very happy to have this opportunity to present the work of Boris Mirkin, a distinguished Russian scholar in the areas of data analysis and decision making methodologies. The monograph is devoted entirely to clustering, a discipline dispersed through many theoretical and application areas, from mathematical statistics and combina­ torial optimization to biology, sociology and organizational structures. It compiles an immense amount of research done to date, including many original Russian de­ velopments never presented to the international community before (for instance, cluster-by-cluster versions of the K-Means method in Chapter 4 or uniform par­ titioning in Chapter 5). The author's approach, approximation clustering, allows him both to systematize a great part of the discipline and to develop many in­ novative methods in the framework of optimization problems. The optimization methods considered are proved to be meaningful in the contexts of data analysis and clustering. The material presented in ...

  10. Biological biomaterials

    Energy Technology Data Exchange (ETDEWEB)

    Jorge-Herrero, E. [Servicio de Cirugia Experimental. Clinica Puerta de Hierro, Madrid (Spain)

    1997-05-01

    There are a number of situations in which substances of biological origin are employed as biomaterials. Most of them are macromolecules derived from isolated connective tissue or the connective tissue itself in membrane form, in both cases, the tissue can be used in its natural form or be chemically treated. In other cases, certain blood vessels can be chemically pretreated and used as vascular prostheses. Proteins such as albumin, collagen and fibrinogen are employed to coat vascular prostheses. Certain polysaccharides have also been tested for use in controlled drug release systems. Likewise, a number of tissues, such as dura mater, bovine pericardium, procine valves and human valves, are used in the preparation of cardiac prostheses. We also use veins from animals or humans in arterial replacement. In none of these cases are the tissues employed dissimilar to the native tissues as they have been chemically modified, becoming a new bio material with different physical and biochemical properties. In short, we find that natural products are being utilized as biomaterials and must be considered as such; thus, it is necessary to study both their chemicobiological and physicomechanical properties. In the present report, we review the current applications, problems and future prospects of some of these biological biomaterials. (Author) 84 refs.

  11. Information Classification on University Websites

    DEFF Research Database (Denmark)

    Nawaz, Ather; Clemmensen, Torkil; Hertzum, Morten

    2011-01-01

    Websites are increasingly used as a medium for providing information to university students. The quality of a university website depends on how well the students’ information classification fits with the structure of the information on the website. This paper investigates the information classifi......Websites are increasingly used as a medium for providing information to university students. The quality of a university website depends on how well the students’ information classification fits with the structure of the information on the website. This paper investigates the information...... classification of 14 Danish and 14 Pakistani students and compares it with the information classification of their university website. Brainstorming, card sorting, and task exploration activities were used to discover similarities and differences in the participating students’ classification of website...... information and their ability to navigate the websites. The results of the study indicate group differences in user classification and related taskperformance differences. The main implications of the study are that (a) the edit distance appears a useful measure in cross-country HCI research and practice...

  12. Ototoxicity (cochleotoxicity) classifications: A review.

    Science.gov (United States)

    Crundwell, Gemma; Gomersall, Phil; Baguley, David M

    2016-01-01

    Drug-mediated ototoxicity, specifically cochleotoxicity, is a concern for patients receiving medications for the treatment of serious illness. A number of classification schemes exist, most of which are based on pure-tone audiometry, in order to assist non-audiological/non-otological specialists in the identification and monitoring of iatrogenic hearing loss. This review identifies the primary classification systems used in cochleototoxicity monitoring. By bringing together classifications published in discipline-specific literature, the paper aims to increase awareness of their relative strengths and limitations in the assessment and monitoring of ototoxic hearing loss and to indicate how future classification systems may improve upon the status-quo. Literature review. PubMed identified 4878 articles containing the search term ototox*. A systematic search identified 13 key classification systems. Cochleotoxicity classification systems can be divided into those which focus on hearing change from a baseline audiogram and those that focus on the functional impact of the hearing loss. Common weaknesses of these grading scales included a lack of sensitivity to small adverse changes in hearing thresholds, a lack of high-frequency audiometry (>8 kHz), and lack of indication of which changes are likely to be clinically significant for communication and quality of life.

  13. Information Classification on University Websites

    DEFF Research Database (Denmark)

    Nawaz, Ather; Clemmensen, Torkil; Hertzum, Morten

    2011-01-01

    Websites are increasingly used as a medium for providing information to university students. The quality of a university website depends on how well the students’ information classification fits with the structure of the information on the website. This paper investigates the information classifi......Websites are increasingly used as a medium for providing information to university students. The quality of a university website depends on how well the students’ information classification fits with the structure of the information on the website. This paper investigates the information...... classification of 14 Danish and 14 Pakistani students and compares it with the information classification of their university website. Brainstorming, card sorting, and task exploration activities were used to discover similarities and differences in the participating students’ classification of website...... information and their ability to navigate the websites. The results of the study indicate group differences in user classification and related task-performance differences. The main implications of the study are that (a) the edit distance appears a useful measure in cross-country HCI research and practice...

  14. HIV classification using coalescent theory

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ming [Los Alamos National Laboratory; Letiner, Thomas K [Los Alamos National Laboratory; Korber, Bette T [Los Alamos National Laboratory

    2008-01-01

    Algorithms for subtype classification and breakpoint detection of HIV-I sequences are based on a classification system of HIV-l. Hence, their quality highly depend on this system. Due to the history of creation of the current HIV-I nomenclature, the current one contains inconsistencies like: The phylogenetic distance between the subtype B and D is remarkably small compared with other pairs of subtypes. In fact, it is more like the distance of a pair of subsubtypes Robertson et al. (2000); Subtypes E and I do not exist any more since they were discovered to be composed of recombinants Robertson et al. (2000); It is currently discussed whether -- instead of CRF02 being a recombinant of subtype A and G -- subtype G should be designated as a circulating recombination form (CRF) nd CRF02 as a subtype Abecasis et al. (2007); There are 8 complete and over 400 partial HIV genomes in the LANL-database which belong neither to a subtype nor to a CRF (denoted by U). Moreover, the current classification system is somehow arbitrary like all complex classification systems that were created manually. To this end, it is desirable to deduce the classification system of HIV systematically by an algorithm. Of course, this problem is not restricted to HIV, but applies to all fast mutating and recombining viruses. Our work addresses the simpler subproblem to score classifications of given input sequences of some virus species (classification denotes a partition of the input sequences in several subtypes and CRFs). To this end, we reconstruct ancestral recombination graphs (ARG) of the input sequences under restrictions determined by the given classification. These restritions are imposed in order to ensure that the reconstructed ARGs do not contradict the classification under consideration. Then, we find the ARG with maximal probability by means of Markov Chain Monte Carlo methods. The probability of the most probable ARG is interpreted as a score for the classification. To our

  15. 5 CFR 1312.7 - Derivative classification.

    Science.gov (United States)

    2010-01-01

    ..., DOWNGRADING, DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Classification and Declassification of National Security Information § 1312.7 Derivative classification. A derivative classification... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Derivative classification. 1312.7 Section...

  16. 32 CFR 2400.15 - Classification guides.

    Science.gov (United States)

    2010-07-01

    ... REGULATIONS TO IMPLEMENT E.O. 12356; OFFICE OF SCIENCE AND TECHNOLOGY POLICY INFORMATION SECURITY PROGRAM Derivative Classification § 2400.15 Classification guides. (a) OSTP shall issue and maintain classification guides to facilitate the proper and uniform derivative classification of information. These guides shall...

  17. 7 CFR 51.1860 - Color classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Color classification. 51.1860 Section 51.1860... STANDARDS) United States Standards for Fresh Tomatoes 1 Color Classification § 51.1860 Color classification... illustrating the color classification requirements, as set forth in this section. This visual aid may be...

  18. 22 CFR 42.11 - Classification symbols.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Classification symbols. 42.11 Section 42.11... NATIONALITY ACT, AS AMENDED Classification and Foreign State Chargeability § 42.11 Classification symbols. A... visa symbol to show the classification of the alien. Immigrants Symbol Class Section of law Immediate...

  19. 28 CFR 345.20 - Position classification.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Position classification. 345.20 Section... INDUSTRIES (FPI) INMATE WORK PROGRAMS Position Classification § 345.20 Position classification. (a) Inmate... the objectives and principles of pay classification as a part of the routine orientation of new FPI...

  20. 7 CFR 51.2284 - Size classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Size classification. 51.2284 Section 51.2284... Size classification. The following classifications are provided to describe the size of any lot... shall conform to the requirements of the specified classification as defined below: (a) Halves. Lot...

  1. 22 CFR 9.8 - Classification challenges.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Classification challenges. 9.8 Section 9.8 Foreign Relations DEPARTMENT OF STATE GENERAL SECURITY INFORMATION REGULATIONS § 9.8 Classification... classification status is improper are expected and encouraged to challenge the classification status of the...

  2. 7 CFR 28.911 - Review classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Review classification. 28.911 Section 28.911... REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Cotton Classification and Market News Service for Producers Classification § 28.911 Review classification. (a) A producer may request one review...

  3. 46 CFR 503.54 - Original classification.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Original classification. 503.54 Section 503.54 Shipping... Program § 503.54 Original classification. (a) No Commission Member or employee has the authority to... classification, it shall be sent to the appropriate agency with original classification authority over the...

  4. 32 CFR 2001.21 - Original classification.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Original classification. 2001.21 Section 2001.21... Markings § 2001.21 Original classification. (a) Primary markings. At the time of original classification... authority. The name and position, or personal identifier, of the original classification authority shall...

  5. Biological effects

    International Nuclear Information System (INIS)

    Trott, K.R.

    1973-01-01

    Following an introduction into the field of cellular radiation effect considering the most important experimental results, the biological significance of the colony formation ability is brought out. The inactivation concept of stem cells does not only prove to be good, according to the present results, in the interpretation of the pathogenesis of acute radiation effects on moult tissue, it also enables chronicle radiation injuries to be interpreted through changes in the fibrous part of the organs. Radiation therapy of tumours can also be explained to a large extent by the radiation effect on the unlimited reproductiveness of tumour cells. The more or less similar dose effect curves for healthy and tumour tissue in practice lead to intermittent irradiation. The dependence of the intermittent doses and intervals on factors such as Elkind recovery, synchronisation, redistribution, reoxygenation, repopulation and regeneration are reviewed. (ORU/LH) [de

  6. Creating biological nanomaterials using synthetic biology

    International Nuclear Information System (INIS)

    Rice, MaryJoe K; Ruder, Warren C

    2014-01-01

    Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems. (review)

  7. Creating biological nanomaterials using synthetic biology.

    Science.gov (United States)

    Rice, MaryJoe K; Ruder, Warren C

    2014-02-01

    Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems.

  8. Featureless classification of light curves

    Science.gov (United States)

    Kügler, S. D.; Gianniotis, N.; Polsterer, K. L.

    2015-08-01

    In the era of rapidly increasing amounts of time series data, classification of variable objects has become the main objective of time-domain astronomy. Classification of irregularly sampled time series is particularly difficult because the data cannot be represented naturally as a vector which can be directly fed into a classifier. In the literature, various statistical features serve as vector representations. In this work, we represent time series by a density model. The density model captures all the information available, including measurement errors. Hence, we view this model as a generalization to the static features which directly can be derived, e.g. as moments from the density. Similarity between each pair of time series is quantified by the distance between their respective models. Classification is performed on the obtained distance matrix. In the numerical experiments, we use data from the OGLE (Optical Gravitational Lensing Experiment) and ASAS (All Sky Automated Survey) surveys and demonstrate that the proposed representation performs up to par with the best currently used feature-based approaches. The density representation preserves all static information present in the observational data, in contrast to a less-complete description by features. The density representation is an upper boundary in terms of information made available to the classifier. Consequently, the predictive power of the proposed classification depends on the choice of similarity measure and classifier, only. Due to its principled nature, we advocate that this new approach of representing time series has potential in tasks beyond classification, e.g. unsupervised learning.

  9. A Semisupervised Cascade Classification Algorithm

    Directory of Open Access Journals (Sweden)

    Stamatis Karlos

    2016-01-01

    Full Text Available Classification is one of the most important tasks of data mining techniques, which have been adopted by several modern applications. The shortage of enough labeled data in the majority of these applications has shifted the interest towards using semisupervised methods. Under such schemes, the use of collected unlabeled data combined with a clearly smaller set of labeled examples leads to similar or even better classification accuracy against supervised algorithms, which use labeled examples exclusively during the training phase. A novel approach for increasing semisupervised classification using Cascade Classifier technique is presented in this paper. The main characteristic of Cascade Classifier strategy is the use of a base classifier for increasing the feature space by adding either the predicted class or the probability class distribution of the initial data. The classifier of the second level is supplied with the new dataset and extracts the decision for each instance. In this work, a self-trained NB∇C4.5 classifier algorithm is presented, which combines the characteristics of Naive Bayes as a base classifier and the speed of C4.5 for final classification. We performed an in-depth comparison with other well-known semisupervised classification methods on standard benchmark datasets and we finally reached to the point that the presented technique has better accuracy in most cases.

  10. A NEW WASTE CLASSIFYING MODEL: HOW WASTE CLASSIFICATION CAN BECOME MORE OBJECTIVE?

    Directory of Open Access Journals (Sweden)

    Burcea Stefan Gabriel

    2015-07-01

    Full Text Available The waste management specialist must be able to identify and analyze waste generation sources and to propose proper solutions to prevent the waste generation and encurage the waste minimisation. In certain situations like implementing an integrated waste management sustem and configure the waste collection methods and capacities, practitioners can face the challenge to classify the generated waste. This will tend to be the more demanding as the literature does not provide a coherent system of criteria required for an objective waste classification process. The waste incineration will determine no doubt a different waste classification than waste composting or mechanical and biological treatment. In this case the main question is what are the proper classification criteria witch can be used to realise an objective waste classification? The article provide a short critical literature review of the existing waste classification criteria and suggests the conclusion that the literature can not provide unitary waste classification system which is unanimously accepted and assumed by ideologists and practitioners. There are various classification criteria and more interesting perspectives in the literature regarding the waste classification, but the most common criteria based on which specialists classify waste into several classes, categories and types are the generation source, physical and chemical features, aggregation state, origin or derivation, hazardous degree etc. The traditional classification criteria divided waste into various categories, subcategories and types; such an approach is a conjectural one because is inevitable that according to the context in which the waste classification is required the used criteria to differ significantly; hence the need to uniformizating the waste classification systems. For the first part of the article it has been used indirect observation research method by analyzing the literature and the various

  11. The normative structure of mathematization in systematic biology.

    Science.gov (United States)

    Sterner, Beckett; Lidgard, Scott

    2014-06-01

    We argue that the mathematization of science should be understood as a normative activity of advocating for a particular methodology with its own criteria for evaluating good research. As a case study, we examine the mathematization of taxonomic classification in systematic biology. We show how mathematization is a normative activity by contrasting its distinctive features in numerical taxonomy in the 1960s with an earlier reform advocated by Ernst Mayr starting in the 1940s. Both Mayr and the numerical taxonomists sought to formalize the work of classification, but Mayr introduced a qualitative formalism based on human judgment for determining the taxonomic rank of populations, while the numerical taxonomists introduced a quantitative formalism based on automated procedures for computing classifications. The key contrast between Mayr and the numerical taxonomists is how they conceptualized the temporal structure of the workflow of classification, specifically where they allowed meta-level discourse about difficulties in producing the classification. Copyright © 2014. Published by Elsevier Ltd.

  12. CLASSIFICATION OF BIODEGRADABLE POLYMERS

    Directory of Open Access Journals (Sweden)

    I. I. Karpunin

    2015-01-01

    Full Text Available The executed investigations have made it possible to ascertain that a morphological structure of starch granules mainly determine technological peculiarities of starch isolation from raw material, its modification and its later use. Morphological structure of starch granules primarily depends on type of plant starch-containing raw material which has been used for its isolation. Class of raw material exerts a strong impact on the shape and size of the granules. Linear “light” amylose chains and “heavy” amylopectin branch chains form a starch granule ultrastructure. X-ray research has proved that starch granules are characterized by presence of interlacing amorphous and crystalline regions. In this case polymer orientation using stretching of the obtained end product influences on its physical and mechanical  indices which are increasing due to polymer orientation. For the purpose of packaging orientation of polymer films can solve such important problems as significant improvement of operational properties, creation of  thermosetting film materials, improvement of qualitative indices of the recycled film.Results of the conducted research have proved the fact that it is necessary to make changes in technology in order to increase biological degradability of the recycled packaging made from polymers and improve physical and mechanical indices. In this regard film production technology presupposes usage of such substances as stark and others which are characterized by rather large presence of branch chains of molecules and interlacing amorphous and crystalline regions. Such approach makes it possible to obtain after-use package which is strong and quickly degradable by micro-organisms.

  13. Risk-based classification system of nanomaterials

    International Nuclear Information System (INIS)

    Tervonen, Tommi; Linkov, Igor; Figueira, Jose Rui; Steevens, Jeffery; Chappell, Mark; Merad, Myriam

    2009-01-01

    Various stakeholders are increasingly interested in the potential toxicity and other risks associated with nanomaterials throughout the different stages of a product's life cycle (e.g., development, production, use, disposal). Risk assessment methods and tools developed and applied to chemical and biological materials may not be readily adaptable for nanomaterials because of the current uncertainty in identifying the relevant physico-chemical and biological properties that adequately describe the materials. Such uncertainty is further driven by the substantial variations in the properties of the original material due to variable manufacturing processes employed in nanomaterial production. To guide scientists and engineers in nanomaterial research and application as well as to promote the safe handling and use of these materials, we propose a decision support system for classifying nanomaterials into different risk categories. The classification system is based on a set of performance metrics that measure both the toxicity and physico-chemical characteristics of the original materials, as well as the expected environmental impacts through the product life cycle. Stochastic multicriteria acceptability analysis (SMAA-TRI), a formal decision analysis method, was used as the foundation for this task. This method allowed us to cluster various nanomaterials in different ecological risk categories based on our current knowledge of nanomaterial physico-chemical characteristics, variation in produced material, and best professional judgments. SMAA-TRI uses Monte Carlo simulations to explore all feasible values for weights, criteria measurements, and other model parameters to assess the robustness of nanomaterial grouping for risk management purposes.

  14. Risk-based classification system of nanomaterials

    Energy Technology Data Exchange (ETDEWEB)

    Tervonen, Tommi, E-mail: t.p.tervonen@rug.n [University of Groningen, Faculty of Economics and Business (Netherlands); Linkov, Igor, E-mail: igor.linkov@usace.army.mi [US Army Research and Development Center (United States); Figueira, Jose Rui, E-mail: figueira@ist.utl.p [Technical University of Lisbon, CEG-IST, Centre for Management Studies, Instituto Superior Tecnico (Portugal); Steevens, Jeffery, E-mail: jeffery.a.steevens@usace.army.mil; Chappell, Mark, E-mail: mark.a.chappell@usace.army.mi [US Army Research and Development Center (United States); Merad, Myriam, E-mail: myriam.merad@ineris.f [INERIS BP 2, Societal Management of Risks Unit/Accidental Risks Division (France)

    2009-05-15

    Various stakeholders are increasingly interested in the potential toxicity and other risks associated with nanomaterials throughout the different stages of a product's life cycle (e.g., development, production, use, disposal). Risk assessment methods and tools developed and applied to chemical and biological materials may not be readily adaptable for nanomaterials because of the current uncertainty in identifying the relevant physico-chemical and biological properties that adequately describe the materials. Such uncertainty is further driven by the substantial variations in the properties of the original material due to variable manufacturing processes employed in nanomaterial production. To guide scientists and engineers in nanomaterial research and application as well as to promote the safe handling and use of these materials, we propose a decision support system for classifying nanomaterials into different risk categories. The classification system is based on a set of performance metrics that measure both the toxicity and physico-chemical characteristics of the original materials, as well as the expected environmental impacts through the product life cycle. Stochastic multicriteria acceptability analysis (SMAA-TRI), a formal decision analysis method, was used as the foundation for this task. This method allowed us to cluster various nanomaterials in different ecological risk categories based on our current knowledge of nanomaterial physico-chemical characteristics, variation in produced material, and best professional judgments. SMAA-TRI uses Monte Carlo simulations to explore all feasible values for weights, criteria measurements, and other model parameters to assess the robustness of nanomaterial grouping for risk management purposes.

  15. A Brief Introduction to Chinese Biological Biological

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Chinese Biological Abstracts sponsored by the Library, the Shanghai Institutes for Biological Sciences, the Biological Documentation and Information Network, all of the Chinese Academy of Sciences, commenced publication in 1987 and was initiated to provide access to the Chinese information in the field of biology.

  16. Rock suitability classification RSC 2012

    Energy Technology Data Exchange (ETDEWEB)

    McEwen, T. (ed.) [McEwen Consulting, Leicester (United Kingdom); Kapyaho, A. [Geological Survey of Finland, Espoo (Finland); Hella, P. [Saanio and Riekkola, Helsinki (Finland); Aro, S.; Kosunen, P.; Mattila, J.; Pere, T.

    2012-12-15

    This report presents Posiva's Rock Suitability Classification (RSC) system, developed for locating suitable rock volumes for repository design and construction. The RSC system comprises both the revised rock suitability criteria and the procedure for the suitability classification during the construction of the repository. The aim of the classification is to avoid such features of the host rock that may be detrimental to the favourable conditions within the repository, either initially or in the long term. This report also discusses the implications of applying the RSC system for the fulfilment of the regulatory requirements concerning the host rock as a natural barrier and the site's overall suitability for hosting a final repository of spent nuclear fuel.

  17. Rock suitability classification RSC 2012

    International Nuclear Information System (INIS)

    McEwen, T.; Kapyaho, A.; Hella, P.; Aro, S.; Kosunen, P.; Mattila, J.; Pere, T.

    2012-12-01

    This report presents Posiva's Rock Suitability Classification (RSC) system, developed for locating suitable rock volumes for repository design and construction. The RSC system comprises both the revised rock suitability criteria and the procedure for the suitability classification during the construction of the repository. The aim of the classification is to avoid such features of the host rock that may be detrimental to the favourable conditions within the repository, either initially or in the long term. This report also discusses the implications of applying the RSC system for the fulfilment of the regulatory requirements concerning the host rock as a natural barrier and the site's overall suitability for hosting a final repository of spent nuclear fuel

  18. Automatic Hierarchical Color Image Classification

    Directory of Open Access Journals (Sweden)

    Jing Huang

    2003-02-01

    Full Text Available Organizing images into semantic categories can be extremely useful for content-based image retrieval and image annotation. Grouping images into semantic classes is a difficult problem, however. Image classification attempts to solve this hard problem by using low-level image features. In this paper, we propose a method for hierarchical classification of images via supervised learning. This scheme relies on using a good low-level feature and subsequently performing feature-space reconfiguration using singular value decomposition to reduce noise and dimensionality. We use the training data to obtain a hierarchical classification tree that can be used to categorize new images. Our experimental results suggest that this scheme not only performs better than standard nearest-neighbor techniques, but also has both storage and computational advantages.

  19. Oral epithelial dysplasia classification systems

    DEFF Research Database (Denmark)

    Warnakulasuriya, S; Reibel, J; Bouquot, J

    2008-01-01

    At a workshop coordinated by the WHO Collaborating Centre for Oral Cancer and Precancer in the United Kingdom issues related to potentially malignant disorders of the oral cavity were discussed by an expert group. The consensus views of the Working Group are presented in a series of papers....... In this report, we review the oral epithelial dysplasia classification systems. The three classification schemes [oral epithelial dysplasia scoring system, squamous intraepithelial neoplasia and Ljubljana classification] were presented and the Working Group recommended epithelial dysplasia grading for routine...... use. Although most oral pathologists possibly recognize and accept the criteria for grading epithelial dysplasia, firstly based on architectural features and then of cytology, there is great variability in their interpretation of the presence, degree and significance of the individual criteria...

  20. SHIP CLASSIFICATION FROM MULTISPECTRAL VIDEOS

    Directory of Open Access Journals (Sweden)

    Frederique Robert-Inacio

    2012-05-01

    Full Text Available Surveillance of a seaport can be achieved by different means: radar, sonar, cameras, radio communications and so on. Such a surveillance aims, on the one hand, to manage cargo and tanker traffic, and, on the other hand, to prevent terrorist attacks in sensitive areas. In this paper an application to video-surveillance of a seaport entrance is presented, and more particularly, the different steps enabling to classify mobile shapes. This classification is based on a parameter measuring the similarity degree between the shape under study and a set of reference shapes. The classification result describes the considered mobile in terms of shape and speed.

  1. Proteomic classification of breast cancer.

    LENUS (Irish Health Repository)

    Kamel, Dalia

    2012-11-01

    Being a significant health problem that affects patients in various age groups, breast cancer has been extensively studied to date. Recently, molecular breast cancer classification has advanced significantly with the availability of genomic profiling technologies. Proteomic technologies have also advanced from traditional protein assays including enzyme-linked immunosorbent assay, immunoblotting and immunohistochemistry to more comprehensive approaches including mass spectrometry and reverse phase protein lysate arrays (RPPA). The purpose of this manuscript is to review the current protein markers that influence breast cancer prediction and prognosis and to focus on novel advances in proteomic classification of breast cancer.

  2. Deep learning for image classification

    Science.gov (United States)

    McCoppin, Ryan; Rizki, Mateen

    2014-06-01

    This paper provides an overview of deep learning and introduces the several subfields of deep learning including a specific tutorial of convolutional neural networks. Traditional methods for learning image features are compared to deep learning techniques. In addition, we present our preliminary classification results, our basic implementation of a convolutional restricted Boltzmann machine on the Mixed National Institute of Standards and Technology database (MNIST), and we explain how to use deep learning networks to assist in our development of a robust gender classification system.

  3. Facial aging: A clinical classification

    Directory of Open Access Journals (Sweden)

    Shiffman Melvin

    2007-01-01

    Full Text Available The purpose of this classification of facial aging is to have a simple clinical method to determine the severity of the aging process in the face. This allows a quick estimate as to the types of procedures that the patient would need to have the best results. Procedures that are presently used for facial rejuvenation include laser, chemical peels, suture lifts, fillers, modified facelift and full facelift. The physician is already using his best judgment to determine which procedure would be best for any particular patient. This classification may help to refine these decisions.

  4. Project implementation : classification of organic soils and classification of marls - training of INDOT personnel.

    Science.gov (United States)

    2012-09-01

    This is an implementation project for the research completed as part of the following projects: SPR3005 Classification of Organic Soils : and SPR3227 Classification of Marl Soils. The methods developed for the classification of both soi...

  5. FACET CLASSIFICATIONS OF E-LEARNING TOOLS

    Directory of Open Access Journals (Sweden)

    Olena Yu. Balalaieva

    2013-12-01

    Full Text Available The article deals with the classification of e-learning tools based on the facet method, which suggests the separation of the parallel set of objects into independent classification groups; at the same time it is not assumed rigid classification structure and pre-built finite groups classification groups are formed by a combination of values taken from the relevant facets. An attempt to systematize the existing classification of e-learning tools from the standpoint of classification theory is made for the first time. Modern Ukrainian and foreign facet classifications of e-learning tools are described; their positive and negative features compared to classifications based on a hierarchical method are analyzed. The original author's facet classification of e-learning tools is proposed.

  6. Using biological indices to classify schizophrenia and other psychotic patients.

    Science.gov (United States)

    Sponheim, S R; Iacono, W G; Thuras, P D; Beiser, M

    2001-07-01

    Although classification of mental disorders using more than clinical description would be desirable, there is scant evidence that available laboratory tests (i.e. biological indices) would provide more valid classifications than current diagnostic systems (e.g. DSM-IV). We used cluster analysis of four biological variables to classify 163 psychotic patients and 83 nonpsychiatric comparison subjects. Analyses revealed a three-cluster solution with the first cluster reflecting electrodermal deviance, the second cluster representing nondeviant biological function, and the third cluster reflecting increased nailfold plexus visibility and ocular motor dysfunction. To assess the construct validity of proband clusters we examined ocular motor performance in 156 first-degree relatives as a function of proband cluster membership. First-degree relatives of third cluster probands exhibited worse ocular motor performance than relatives of other cluster probands. Additionally, better classification sensitivity and specificity were obtained for the relatives when they were grouped by proband cluster than by proband DSM-IV diagnosis. When a single proband characteristic (i.e. eyetracking performance) was used to group relatives, classification sensitivity and specificity failed to significantly increase over grouping by proband DSM-IV diagnosis. Multivariate biologically defined clusters may offer an advantage over DSM-IV classification when examining nosology and etiology of psychotic disorders.

  7. Definition and classification of epilepsy. Classification of epileptic seizures 2016

    Directory of Open Access Journals (Sweden)

    K. Yu. Mukhin

    2017-01-01

    Full Text Available Epilepsy is one of the most common neurological diseases, especially in childhood and adolescence. The incidence varies from 15 to 113 cases per 100 000 population with the maximum among children under 1 year old. The prevalence of epilepsy is high, ranging from 5 to 8 cases (in some regions – 10 cases per 1000 children under 15 years old. Classification of the disease has great importance for diagnosis, treatment and prognosis. The article presents a novel strategy for classification of epileptic seizures, developed in 2016. It contains a number of brand new concepts, including a very important one, saying that some seizures, previously considered as generalized or focal only, can be, in fact, both focal and generalized. They include tonic, atonic, myoclonic seizures and epileptic spasms. The term “secondarily generalized seizure” is replace by the term “bilateral tonic-clonic seizure” (as soon as it is not a separate type of epileptic seizures, and the term reflects the spread of discharge from any area of cerebral cortex and evolution of any types of focal seizures. International League Against Epilepsy recommends to abandon the term “pseudo-epileptic seizures” and replace it by the term “psychogenic non-epileptic seizures”. If a doctor is not sure that seizures have epileptic nature, the term “paroxysmal event” should be used without specifying the disease. The conception of childhood epileptic encephalopathies, developed within this novel classification project, is one of the most significant achievements, since in this case not only the seizures, but even epileptiform activity can induce severe disorders of higher mental functions. In addition to detailed description of the new strategy for classification of epileptic seizures, the article contains a comprehensive review of the existing principles of epilepsy and epileptic seizures classification.

  8. On the classification of long non-coding RNAs

    KAUST Repository

    Ma, Lina

    2013-06-01

    Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide variety of important biological processes. To make easier interpretation of lncRNA functionality and conduct deep mining on these transcribed sequences, it is convenient to classify lncRNAs into different groups. Here, we summarize classification methods of lncRNAs according to their four major features, namely, genomic location and context, effect exerted on DNA sequences, mechanism of functioning and their targeting mechanism. In combination with the presently available function annotations, we explore potential relationships between different classification categories, and generalize and compare biological features of different lncRNAs within each category. Finally, we present our view on potential further studies. We believe that the classifications of lncRNAs as indicated above are of fundamental importance for lncRNA studies, helpful for further investigation of specific lncRNAs, for formulation of new hypothesis based on different features of lncRNA and for exploration of the underlying lncRNA functional mechanisms. © 2013 Landes Bioscience.

  9. Dolphins. LC Science Tracer Bullet.

    Science.gov (United States)

    Niskern, Diana, Comp.

    The family Delphinidae is the largest family of toothed whales. It includes not only those mammals commonly referred to as dolphins, such as the bottlenosed dolphin often seen in captivity, but also the killer whale. This literature and resources guide is not intended to be a comprehensive bibliography on dolphins; the guide is designed--as the…

  10. Tribology. LC Science Tracer Bullet.

    Science.gov (United States)

    Havas, George D., Comp.

    Tribology is the science and technology of interacting surfaces in relative motion. It incorporates a number of scientific fields, including friction, wear, lubrication, materials science, and various branches of surface physics and surface chemistry. Tribology forms a vital part of engineering science. The interacting surfaces may be on machinery…

  11. Algae. LC Science Tracer Bullet.

    Science.gov (United States)

    Niskern, Diana, Comp.

    The plants and plantlike organisms informally grouped together as algae show great diversity of form and size and occur in a wide variety of habitats. These extremely important photosynthesizers are also economically significant. For example, some species contaminate water supplies; others provide food for aquatic animals and for man; still others…

  12. Depleted uranium - 'the silver bullet'

    International Nuclear Information System (INIS)

    Munoz-Ferrada, C.; Wollongong University, NSW

    2001-01-01

    Article 35 of the Geneva protocols, signed by 150 countries in 1949 and an additional protocol signed from 1977 onwards prohibited the use of weapons that cause and inflict unnecessary injury and suffering. In the recent wars such as Bosnia, Kosovo and the Gulf War, more than 31,000 missiles were launched against enemy lines containing DU and more than 300 tonnes of DU during the Gulf War alone. DU is a radioactive and toxic element. In humans it can cause lung cancer, damage to the liver and kidney affecting the bone marrow and consequently destroying stem cells that form the white cells resulting in mutations and the long lasting effect of genetic damage

  13. Agriculture classification using POLSAR data

    DEFF Research Database (Denmark)

    Skriver, Henning; Dall, Jørgen; Ferro-Famil, Laurent

    2005-01-01

    of their components) show strongly preferred orientations, such as the stalks or ears of cereals. The importance of SAR polarimetry in crop classification arises principally because polarisation is sen-sitive to orientation. Hence it provides a means to distinguish crops with different canopy archi-tectures. Detailed...

  14. Urogenital tuberculosis: definition and classification.

    Science.gov (United States)

    Kulchavenya, Ekaterina

    2014-10-01

    To improve the approach to the diagnosis and management of urogenital tuberculosis (UGTB), we need clear and unique classification. UGTB remains an important problem, especially in developing countries, but it is often an overlooked disease. As with any other infection, UGTB should be cured by antibacterial therapy, but because of late diagnosis it may often require surgery. Scientific literature dedicated to this problem was critically analyzed and juxtaposed with the author's own more than 30 years' experience in tuberculosis urology. The conception, terms and definition were consolidated into one system; classification stage by stage as well as complications are presented. Classification of any disease includes dispersion on forms and stages and exact definitions for each stage. Clinical features and symptoms significantly vary between different forms and stages of UGTB. A simple diagnostic algorithm was constructed. UGTB is multivariant disease and a standard unified approach to it is impossible. Clear definition as well as unique classification are necessary for real estimation of epidemiology and the optimization of therapy. The term 'UGTB' has insufficient information in order to estimate therapy, surgery and prognosis, or to evaluate the epidemiology.

  15. Real time automatic scene classification

    NARCIS (Netherlands)

    Verbrugge, R.; Israël, Menno; Taatgen, N.; van den Broek, Egon; van der Putten, Peter; Schomaker, L.; den Uyl, Marten J.

    2004-01-01

    This work has been done as part of the EU VICAR (IST) project and the EU SCOFI project (IAP). The aim of the first project was to develop a real time video indexing classification annotation and retrieval system. For our systems, we have adapted the approach of Picard and Minka [3], who categorized

  16. Unsupervised classification of variable stars

    Science.gov (United States)

    Valenzuela, Lucas; Pichara, Karim

    2018-03-01

    During the past 10 years, a considerable amount of effort has been made to develop algorithms for automatic classification of variable stars. That has been primarily achieved by applying machine learning methods to photometric data sets where objects are represented as light curves. Classifiers require training sets to learn the underlying patterns that allow the separation among classes. Unfortunately, building training sets is an expensive process that demands a lot of human efforts. Every time data come from new surveys; the only available training instances are the ones that have a cross-match with previously labelled objects, consequently generating insufficient training sets compared with the large amounts of unlabelled sources. In this work, we present an algorithm that performs unsupervised classification of variable stars, relying only on the similarity among light curves. We tackle the unsupervised classification problem by proposing an untraditional approach. Instead of trying to match classes of stars with clusters found by a clustering algorithm, we propose a query-based method where astronomers can find groups of variable stars ranked by similarity. We also develop a fast similarity function specific for light curves, based on a novel data structure that allows scaling the search over the entire data set of unlabelled objects. Experiments show that our unsupervised model achieves high accuracy in the classification of different types of variable stars and that the proposed algorithm scales up to massive amounts of light curves.

  17. Automatic indexing, compiling and classification

    International Nuclear Information System (INIS)

    Andreewsky, Alexandre; Fluhr, Christian.

    1975-06-01

    A review of the principles of automatic indexing, is followed by a comparison and summing-up of work by the authors and by a Soviet staff from the Moscou INFORM-ELECTRO Institute. The mathematical and linguistic problems of the automatic building of thesaurus and automatic classification are examined [fr

  18. Aphasia Classification Using Neural Networks

    DEFF Research Database (Denmark)

    Axer, H.; Jantzen, Jan; Berks, G.

    2000-01-01

    A web-based software model (http://fuzzy.iau.dtu.dk/aphasia.nsf) was developed as an example for classification of aphasia using neural networks. Two multilayer perceptrons were used to classify the type of aphasia (Broca, Wernicke, anomic, global) according to the results in some subtests...

  19. Classification Accuracy Is Not Enough

    DEFF Research Database (Denmark)

    Sturm, Bob L.

    2013-01-01

    A recent review of the research literature evaluating music genre recognition (MGR) systems over the past two decades shows that most works (81\\%) measure the capacity of a system to recognize genre by its classification accuracy. We show here, by implementing and testing three categorically...

  20. Is classification necessary after Google?

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2012-01-01

    believe that the activity of “classification” is not worth the effort, as search engines can be improved without the heavy cost of providing metadata. Design/methodology/approach – The basic issue in classification is seen as providing criteria for deciding whether A should be classified as X...

  1. Data Augmentation for Plant Classification

    NARCIS (Netherlands)

    Pawara, Pornntiwa; Okafor, Emmanuel; Schomaker, Lambertus; Wiering, Marco

    2017-01-01

    Data augmentation plays a crucial role in increasing the number of training images, which often aids to improve classification performances of deep learning techniques for computer vision problems. In this paper, we employ the deep learning framework and determine the effects of several

  2. Climatic classification of the Karst

    International Nuclear Information System (INIS)

    Eslava Ramirez Jesus Antonio; Bahamon Ayala, Sandra Marcela; Lopez Romero Maria Ines

    2000-01-01

    Climate is one the main factors in forming or modifying Karsts, or its resulting forms. The determining climatic elements of Karst characteristics are humidity, air circulation and temperature. Many Karstic processes show characteristics corresponding to a given climate sequence. In the present article we discuss the relation between climate and Karst as well as a climate classification based on the structure of the Karsts

  3. CLASSIFICATION OF LEARNING MANAGEMENT SYSTEMS

    Directory of Open Access Journals (Sweden)

    Yu. B. Popova

    2016-01-01

    Full Text Available Using of information technologies and, in particular, learning management systems, increases opportunities of teachers and students in reaching their goals in education. Such systems provide learning content, help organize and monitor training, collect progress statistics and take into account the individual characteristics of each user. Currently, there is a huge inventory of both paid and free systems are physically located both on college servers and in the cloud, offering different features sets of different licensing scheme and the cost. This creates the problem of choosing the best system. This problem is partly due to the lack of comprehensive classification of such systems. Analysis of more than 30 of the most common now automated learning management systems has shown that a classification of such systems should be carried out according to certain criteria, under which the same type of system can be considered. As classification features offered by the author are: cost, functionality, modularity, keeping the customer’s requirements, the integration of content, the physical location of a system, adaptability training. Considering the learning management system within these classifications and taking into account the current trends of their development, it is possible to identify the main requirements to them: functionality, reliability, ease of use, low cost, support for SCORM standard or Tin Can API, modularity and adaptability. According to the requirements at the Software Department of FITR BNTU under the guidance of the author since 2009 take place the development, the use and continuous improvement of their own learning management system.

  4. Crop Classification by Polarimetric SAR

    DEFF Research Database (Denmark)

    Skriver, Henning; Svendsen, Morten Thougaard; Nielsen, Flemming

    1999-01-01

    Polarimetric SAR-data of agricultural fields have been acquired by the Danish polarimetric L- and C-band SAR (EMISAR) during a number of missions at the Danish agricultural test site Foulum during 1995. The data are used to study the classification potential of polarimetric SAR data using...

  5. Emotions Classification for Arabic Tweets

    African Journals Online (AJOL)

    pc

    2018-03-05

    Mar 5, 2018 ... learning methods for referring to all areas of detecting, analyzing, and classifying ... In this paper, an adaptive model is proposed for emotions classification of ... WEKA data mining tool is used to implement this model and evaluate the ... defined using vector representation, storing a numerical. "importance" ...

  6. Correlation Dimension Estimation for Classification

    Czech Academy of Sciences Publication Activity Database

    Jiřina, Marcel; Jiřina jr., M.

    2006-01-01

    Roč. 1, č. 3 (2006), s. 547-557 ISSN 1895-8648 R&D Projects: GA MŠk(CZ) 1M0567 Institutional research plan: CEZ:AV0Z10300504 Keywords : correlation dimension * probability density estimation * classification * UCI MLR Subject RIV: BA - General Mathematics

  7. MicroRNAs in the Tumor Biology of Soft Tissue Sarcomas

    NARCIS (Netherlands)

    C.M.M. Gits (Caroline)

    2013-01-01

    markdownabstract__Abstract__ Soft tissue sarcomas represent a rare, heterogeneous group of mesenchymal tumors. In sarcomas, histological classification, prediction of clinical behaviour and prognosis, and targeted treatment is often a challenge. A better understanding of the biology of soft

  8. Functional Basis of Microorganism Classification.

    Science.gov (United States)

    Zhu, Chengsheng; Delmont, Tom O; Vogel, Timothy M; Bromberg, Yana

    2015-08-01

    Correctly identifying nearest "neighbors" of a given microorganism is important in industrial and clinical applications where close relationships imply similar treatment. Microbial classification based on similarity of physiological and genetic organism traits (polyphasic similarity) is experimentally difficult and, arguably, subjective. Evolutionary relatedness, inferred from phylogenetic markers, facilitates classification but does not guarantee functional identity between members of the same taxon or lack of similarity between different taxa. Using over thirteen hundred sequenced bacterial genomes, we built a novel function-based microorganism classification scheme, functional-repertoire similarity-based organism network (FuSiON; flattened to fusion). Our scheme is phenetic, based on a network of quantitatively defined organism relationships across the known prokaryotic space. It correlates significantly with the current taxonomy, but the observed discrepancies reveal both (1) the inconsistency of functional diversity levels among different taxa and (2) an (unsurprising) bias towards prioritizing, for classification purposes, relatively minor traits of particular interest to humans. Our dynamic network-based organism classification is independent of the arbitrary pairwise organism similarity cut-offs traditionally applied to establish taxonomic identity. Instead, it reveals natural, functionally defined organism groupings and is thus robust in handling organism diversity. Additionally, fusion can use organism meta-data to highlight the specific environmental factors that drive microbial diversification. Our approach provides a complementary view to cladistic assignments and holds important clues for further exploration of microbial lifestyles. Fusion is a more practical fit for biomedical, industrial, and ecological applications, as many of these rely on understanding the functional capabilities of the microbes in their environment and are less concerned with

  9. Functional Basis of Microorganism Classification

    Science.gov (United States)

    Zhu, Chengsheng; Delmont, Tom O.; Vogel, Timothy M.; Bromberg, Yana

    2015-01-01

    Correctly identifying nearest “neighbors” of a given microorganism is important in industrial and clinical applications where close relationships imply similar treatment. Microbial classification based on similarity of physiological and genetic organism traits (polyphasic similarity) is experimentally difficult and, arguably, subjective. Evolutionary relatedness, inferred from phylogenetic markers, facilitates classification but does not guarantee functional identity between members of the same taxon or lack of similarity between different taxa. Using over thirteen hundred sequenced bacterial genomes, we built a novel function-based microorganism classification scheme, functional-repertoire similarity-based organism network (FuSiON; flattened to fusion). Our scheme is phenetic, based on a network of quantitatively defined organism relationships across the known prokaryotic space. It correlates significantly with the current taxonomy, but the observed discrepancies reveal both (1) the inconsistency of functional diversity levels among different taxa and (2) an (unsurprising) bias towards prioritizing, for classification purposes, relatively minor traits of particular interest to humans. Our dynamic network-based organism classification is independent of the arbitrary pairwise organism similarity cut-offs traditionally applied to establish taxonomic identity. Instead, it reveals natural, functionally defined organism groupings and is thus robust in handling organism diversity. Additionally, fusion can use organism meta-data to highlight the specific environmental factors that drive microbial diversification. Our approach provides a complementary view to cladistic assignments and holds important clues for further exploration of microbial lifestyles. Fusion is a more practical fit for biomedical, industrial, and ecological applications, as many of these rely on understanding the functional capabilities of the microbes in their environment and are less concerned

  10. 5th Conference of the International Federation of Classification Societies

    CERN Document Server

    Yajima, Keiji; Bock, Hans-Hermann; Ohsumi, Noboru; Tanaka, Yutaka; Baba, Yasumasa

    1998-01-01

    This volume, Data Science, Classification, and Related Methods, contains a selection of papers presented at the Fifth Conference of the International Federation of Oassification Societies (IFCS-96), which was held in Kobe, Japan, from March 27 to 30,1996. The volume covers a wide range of topics and perspectives in the growing field of data science, including theoretical and methodological advances in domains relating to data gathering, classification and clustering, exploratory and multivariate data analysis, and knowledge discovery and seeking. It gives a broad view of the state of the art and is intended for those in the scientific community who either develop new data analysis methods or gather data and use search tools for analyzing and interpreting large and complex data sets. Presenting a wide field of applications, this book is of interest not only to data analysts, mathematicians, and statisticians but also to scientists from many areas and disciplines concerned with complex data: medicine, biology, ...

  11. Single-Rooted Extraction Sockets: Classification and Treatment Protocol.

    Science.gov (United States)

    El Chaar, Edgar; Oshman, Sarah; Fallah Abed, Pooria

    2016-09-01

    Clinicians have many treatment techniques from which to choose when extracting a failing tooth and replacing it with an implant-supported restoration and when successful management of an extraction socket during the course of tooth replacement is necessary to achieve predictable and esthetic outcomes. This article presents a straightforward, yet thorough, classification for extraction sockets of single-rooted teeth and provides guidance to clinicians in the selection of appropriate and predictable treatment. The presented classification of extraction sockets for single-rooted teeth focuses on the topography of the extraction socket, while the protocol for treatment of each socket type factors in the shape of the remaining bone, the biotype, and the location of the socket whether it be in the mandible or maxilla. This system is based on the biologic foundations of wound healing and can help guide clinicians to successful treatment outcomes.

  12. Segmentation and classification of cell cycle phases in fluorescence imaging.

    Science.gov (United States)

    Ersoy, Ilker; Bunyak, Filiz; Chagin, Vadim; Cardoso, M Christina; Palaniappan, Kannappan

    2009-01-01

    Current chemical biology methods for studying spatiotemporal correlation between biochemical networks and cell cycle phase progression in live-cells typically use fluorescence-based imaging of fusion proteins. Stable cell lines expressing fluorescently tagged protein GFP-PCNA produce rich, dynamically varying sub-cellular foci patterns characterizing the cell cycle phases, including the progress during the S-phase. Variable fluorescence patterns, drastic changes in SNR, shape and position changes and abundance of touching cells require sophisticated algorithms for reliable automatic segmentation and cell cycle classification. We extend the recently proposed graph partitioning active contours (GPAC) for fluorescence-based nucleus segmentation using regional density functions and dramatically improve its efficiency, making it scalable for high content microscopy imaging. We utilize surface shape properties of GFP-PCNA intensity field to obtain descriptors of foci patterns and perform automated cell cycle phase classification, and give quantitative performance by comparing our results to manually labeled data.

  13. Screening and classification of ceramic powders

    Science.gov (United States)

    Miwa, S.

    1983-01-01

    A summary is given of the classification technology of ceramic powders. Advantages and disadvantages of the wet and dry screening and classification methods are discussed. Improvements of wind force screening devices are described.

  14. 5 CFR 1312.3 - Classification requirements.

    Science.gov (United States)

    2010-01-01

    ..., DOWNGRADING, DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Classification and Declassification of National Security Information § 1312.3 Classification requirements. United States citizens must...; (5) Scientific, technological, or economic matters relating to the national security; (6) United...

  15. 14 CFR 1203.412 - Classification guides.

    Science.gov (United States)

    2010-01-01

    ... of the classification designations (i.e., Top Secret, Secret or Confidential) apply to the identified... writing by an official with original Top Secret classification authority; the identity of the official...

  16. Classification guide: Paralympic Games London 2012

    OpenAIRE

    2013-01-01

    The London 2012 Paralympic Games Classification Guide is designed to provide National Paralympic Committees (NPCs) and International Paralympic Sport Federations (IPSFs) with information about the classification policies and procedures that will apply to the London 2012 Paralympic Games.

  17. Classification guide: Sochi 2014 Paralympic Winter Games

    OpenAIRE

    2014-01-01

    The Sochi 2014 Paralympic Winter Games classification guide is designed to provide National Paralympic Committees (NPCs) and International Federations (IFs) with information about the classification policies and procedures that will apply to the Sochi 2014 Paralympic Winter Games.

  18. Improvement of Classification of Enterprise Circulating Funds

    OpenAIRE

    Rohanova Hanna O.

    2014-01-01

    The goal of the article lies in revelation of possibilities of increase of efficiency of managing enterprise circulating funds by means of improvement of their classification features. Having analysed approaches of many economists to classification of enterprise circulating funds, systemised and supplementing them, the article offers grouping classification features of enterprise circulating funds. In the result of the study the article offers an expanded classification of circulating funds, ...

  19. Bio-geographic classification of the Caspian Sea

    Science.gov (United States)

    Fendereski, F.; Vogt, M.; Payne, M. R.; Lachkar, Z.; Gruber, N.; Salmanmahiny, A.; Hosseini, S. A.

    2014-03-01

    Like other inland seas, the Caspian Sea (CS) has been influenced by climate change and anthropogenic disturbance during recent decades, yet the scientific understanding of this water body remains poor. In this study, an eco-geographical classification of the CS based on physical information derived from space and in-situ data is developed and tested against a set of biological observations. We used a two-step classification procedure, consisting of (i) a data reduction with self-organizing maps (SOMs) and (ii) a synthesis of the most relevant features into a reduced number of marine ecoregions using the Hierarchical Agglomerative Clustering (HAC) method. From an initial set of 12 potential physical variables, 6 independent variables were selected for the classification algorithm, i.e., sea surface temperature (SST), bathymetry, sea ice, seasonal variation of sea surface salinity (DSSS), total suspended matter (TSM) and its seasonal variation (DTSM). The classification results reveal a robust separation between the northern and the middle/southern basins as well as a separation of the shallow near-shore waters from those off-shore. The observed patterns in ecoregions can be attributed to differences in climate and geochemical factors such as distance from river, water depth and currents. A comparison of the annual and monthly mean Chl a concentrations between the different ecoregions shows significant differences (Kruskal-Wallis rank test, P qualitative evaluation of differences in community composition based on recorded presence-absence patterns of 27 different species of plankton, fish and benthic invertebrate also confirms the relevance of the ecoregions as proxies for habitats with common biological characteristics.

  20. 10 CFR 61.55 - Waste classification.

    Science.gov (United States)

    2010-01-01

    ... REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.55 Waste classification. (a) Classification of waste for near surface disposal—(1) Considerations. Determination of the classification of radioactive waste involves two...

  1. 6 CFR 7.26 - Derivative classification.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Derivative classification. 7.26 Section 7.26 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CLASSIFIED NATIONAL SECURITY INFORMATION Classified Information § 7.26 Derivative classification. (a) Derivative classification is defined...

  2. 22 CFR 9.6 - Derivative classification.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Derivative classification. 9.6 Section 9.6 Foreign Relations DEPARTMENT OF STATE GENERAL SECURITY INFORMATION REGULATIONS § 9.6 Derivative classification. (a) Definition. Derivative classification is the incorporating, paraphrasing, restating or...

  3. 46 CFR 76.50-5 - Classification.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Classification. 76.50-5 Section 76.50-5 Shipping COAST... Classification. (a) Hand portable fire extinguishers and semiportable fire extinguishing systems shall be... extinguishing systems are set forth in table 76.50-5(c). Table 76.50-5(c) Classification Type Size Soda acid and...

  4. 12 CFR 560.160 - Asset classification.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Asset classification. 560.160 Section 560.160... Lending and Investment Provisions Applicable to all Savings Associations § 560.160 Asset classification... consistent with, or reconcilable to, the asset classification system used by OTS in its Thrift Activities...

  5. 14 CFR 298.3 - Classification.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Classification. 298.3 Section 298.3... REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS General § 298.3 Classification. (a) There is hereby established a classification of air carriers, designated as “air taxi operators,” which...

  6. 6 CFR 7.30 - Classification challenges.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Classification challenges. 7.30 Section 7.30... INFORMATION Classified Information § 7.30 Classification challenges. (a) Authorized holders of information... classified are encouraged and expected to challenge the classification status of that information pursuant to...

  7. 14 CFR 1203.701 - Classification.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Classification. 1203.701 Section 1203.701... Government Information § 1203.701 Classification. (a) Foreign government information that is classified by a foreign entity shall either retain its original classification designation or be marked with a United...

  8. 32 CFR 1602.7 - Classification.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Classification. 1602.7 Section 1602.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.7 Classification. Classification is the exercise of the power to determine claims or questions with respect to...

  9. 32 CFR 644.426 - Classification.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Classification. 644.426 Section 644.426 National... HANDBOOK Disposal Disposal of Fee-Owned Real Property and Easement Interests § 644.426 Classification... required by the special acts, classification will be coordinated with the interested Federal agency. The...

  10. 46 CFR Sec. 18 - Group classification.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Group classification. Sec. 18 Section 18 Shipping... Sec. 18 Group classification. In the preparation of specifications, Job Orders, Supplemental Job... inserted thereon: Number Classification 41 Maintenance Repairs (deck, engine and stewards department...

  11. 10 CFR 1045.37 - Classification guides.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Classification guides. 1045.37 Section 1045.37 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.37 Classification guides...

  12. 46 CFR 193.50-5 - Classification.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Classification. 193.50-5 Section 193.50-5 Shipping COAST... Details § 193.50-5 Classification. (a) Hand portable fire extinguishers and semiportable fire...) Classification Type Size Soda-acid and water, gals. Foam, gals. Carbon dioxide, lbs. Dry chemical, lbs. A II 21/2...

  13. Border Lakes land-cover classification

    Science.gov (United States)

    Marvin Bauer; Brian Loeffelholz; Doug. Shinneman

    2009-01-01

    This document contains metadata and description of land-cover classification of approximately 5.1 million acres of land bordering Minnesota, U.S.A. and Ontario, Canada. The classification focused on the separation and identification of specific forest-cover types. Some separation of the nonforest classes also was performed. The classification was derived from multi-...

  14. 22 CFR 9a.4 - Classification.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Classification. 9a.4 Section 9a.4 Foreign... ENERGY PROGRAMS; RELATED MATERIAL § 9a.4 Classification. (a) Section 1 of E.O. 11932, August 4, 1976.... If the officer determines that the information or material warrants classification, he shall assign...

  15. 75 FR 10529 - Mail Classification Change

    Science.gov (United States)

    2010-03-08

    ... POSTAL REGULATORY COMMISSION [Docket Nos. MC2010-19; Order No. 415] Mail Classification Change...-filed Postal Service request to make a minor modification to the Mail Classification Schedule. The.... concerning a change in classification which reflects a change in terminology from Bulk Mailing Center (BMC...

  16. 7 CFR 51.1903 - Size classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Size classification. 51.1903 Section 51.1903... STANDARDS) United States Consumer Standards for Fresh Tomatoes Size and Maturity Classification § 51.1903 Size classification. The following terms may be used for describing the size of the tomatoes in any lot...

  17. 33 CFR 154.1216 - Facility classification.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Facility classification. 154.1216... Vegetable Oils Facilities § 154.1216 Facility classification. (a) The Coast Guard classifies facilities that... classification of a facility that handles, stores, or transports animal fats or vegetable oils. The COTP may...

  18. 7 CFR 1794.31 - Classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Classification. 1794.31 Section 1794.31 Agriculture... Classification. (a) Electric and telecommunications programs. RUS will normally determine the proper environmental classification of projects based on its evaluation of the project description set forth in the...

  19. 76 FR 47614 - Mail Classification Change

    Science.gov (United States)

    2011-08-05

    ... POSTAL REGULATORY COMMISSION [Docket No. MC2011-27; Order No. 785] Mail Classification Change...-filed Postal Service request for a change in classification to the ``Reply Rides Free'' program. The... Service filed a notice of classification change pursuant to 39 CFR 3020.90 and 3020.91 concerning the...

  20. 32 CFR 1602.13 - Judgmental Classification.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Judgmental Classification. 1602.13 Section 1602.13 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.13 Judgmental Classification. A classification action relating to a registrant's claim for...