WorldWideScience

Sample records for biological assessment final

  1. Grays River Watershed and Biological Assessment Final Report 2006.

    Energy Technology Data Exchange (ETDEWEB)

    May, Christopher W.; McGrath, Kathleen E.; Geist, David R. [Pacific Northwest National Laboratory; Abbe, Timothy; Barton, Chase [Herrera Environmental Consultants, Inc.

    2008-02-04

    The Grays River Watershed and Biological Assessment was funded to address degradation and loss of spawning habitat for chum salmon (Onchorhynchus keta) and fall Chinook salmon (Onchoryhnchus tshawytscha). In 1999, the National Marine Fisheries Service listed lower Columbia River chum salmon as a threatened Evolutionarily Significant Unit (ESU) under the Endangered Species Act of 1973 (ESA). The Grays River watershed is one of two remaining significant chum salmon spawning locations in this ESU. Runs of Grays River chum and Chinook salmon have declined significantly during the past century, largely because of damage to spawning habitat associated with timber harvest and agriculture in the watershed. In addition, approximately 20-25% of the then-remaining chum salmon spawning habitat was lost during a 1999 channel avulsion that destroyed an important artificial spawning channel operated by the Washington Department of Fish and Wildlife (WDFW). Although the lack of stable, high-quality spawning habitat is considered the primary physical limitation on Grays River chum salmon production today, few data are available to guide watershed management and channel restoration activities. The objectives of the Grays River Watershed and Biological Assessment project were to (1) perform a comprehensive watershed and biological analysis, including hydrologic, geomorphic, and ecological assessments; (2) develop a prioritized list of actions that protect and restore critical chum and Chinook salmon spawning habitat in the Grays River based on comprehensive geomorphic, hydrologic, and stream channel assessments; and (3) gain a better understanding of chum and Chinook salmon habitat requirements and survival within the lower Columbia River and the Grays River. The watershed-based approach to river ecosystem restoration relies on a conceptual framework that describes general relationships between natural landscape characteristics, watershed-scale habitat-forming processes, aquatic

  2. Grays River Watershed and Biological Assessment, 2006 Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    May, Christopher; Geist, David [Pacific Northwest National Laboratory

    2007-04-01

    The Grays River Watershed and Biological Assessment was funded to address degradation and loss of spawning habitat for chum salmon (Onchorhynchus keta) and fall Chinook salmon (Onchoryhnchus tshawytscha). In 1999, the National Marine Fisheries Service listed lower Columbia River chum salmon as a threatened Evolutionarily Significant Unit (ESU) under the Endangered Species Act of 1973 (ESA). The Grays River watershed is one of two remaining significant chum salmon spawning locations in this ESU. Runs of Grays River chum and Chinook salmon have declined significantly during the past century, largely because of damage to spawning habitat associated with timber harvest and agriculture in the watershed. In addition, approximately 20-25% of the then-remaining chum salmon spawning habitat was lost during a 1999 channel avulsion that destroyed an important artificial spawning channel operated by the Washington Department of Fish and Wildlife (WDFW). Although the lack of stable, high-quality spawning habitat is considered the primary physical limitation on Grays River chum salmon production today, few data are available to guide watershed management and channel restoration activities. The objectives of the Grays River Watershed and Biological Assessment project were to (1) perform a comprehensive watershed and biological analysis, including hydrologic, geomorphic, and ecological assessments; (2) develop a prioritized list of actions that protect and restore critical chum and Chinook salmon spawning habitat in the Grays River based on comprehensive geomorphic, hydrologic, and stream channel assessments; and (3) gain a better understanding of chum and Chinook salmon habitat requirements and survival within the lower Columbia River and the Grays River. The watershed-based approach to river ecosystem restoration relies on a conceptual framework that describes general relationships between natural landscape characteristics, watershed-scale habitat-forming processes, aquatic

  3. Grays River Watershed and Biological Assessment, 2006 Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    May, Christopher; Geist, David [Pacific Northwest National Laboratory

    2007-04-01

    The Grays River Watershed and Biological Assessment was funded to address degradation and loss of spawning habitat for chum salmon (Onchorhynchus keta) and fall Chinook salmon (Onchoryhnchus tshawytscha). In 1999, the National Marine Fisheries Service listed lower Columbia River chum salmon as a threatened Evolutionarily Significant Unit (ESU) under the Endangered Species Act of 1973 (ESA). The Grays River watershed is one of two remaining significant chum salmon spawning locations in this ESU. Runs of Grays River chum and Chinook salmon have declined significantly during the past century, largely because of damage to spawning habitat associated with timber harvest and agriculture in the watershed. In addition, approximately 20-25% of the then-remaining chum salmon spawning habitat was lost during a 1999 channel avulsion that destroyed an important artificial spawning channel operated by the Washington Department of Fish and Wildlife (WDFW). Although the lack of stable, high-quality spawning habitat is considered the primary physical limitation on Grays River chum salmon production today, few data are available to guide watershed management and channel restoration activities. The objectives of the Grays River Watershed and Biological Assessment project were to (1) perform a comprehensive watershed and biological analysis, including hydrologic, geomorphic, and ecological assessments; (2) develop a prioritized list of actions that protect and restore critical chum and Chinook salmon spawning habitat in the Grays River based on comprehensive geomorphic, hydrologic, and stream channel assessments; and (3) gain a better understanding of chum and Chinook salmon habitat requirements and survival within the lower Columbia River and the Grays River. The watershed-based approach to river ecosystem restoration relies on a conceptual framework that describes general relationships between natural landscape characteristics, watershed-scale habitat-forming processes, aquatic

  4. Grays River Watershed and Biological Assessment Final Report 2006.

    Energy Technology Data Exchange (ETDEWEB)

    May, Christopher W.; McGrath, Kathleen E.; Geist, David R. [Pacific Northwest National Laboratory; Abbe, Timothy; Barton, Chase [Herrera Environmental Consultants, Inc.

    2008-02-04

    The Grays River Watershed and Biological Assessment was funded to address degradation and loss of spawning habitat for chum salmon (Onchorhynchus keta) and fall Chinook salmon (Onchoryhnchus tshawytscha). In 1999, the National Marine Fisheries Service listed lower Columbia River chum salmon as a threatened Evolutionarily Significant Unit (ESU) under the Endangered Species Act of 1973 (ESA). The Grays River watershed is one of two remaining significant chum salmon spawning locations in this ESU. Runs of Grays River chum and Chinook salmon have declined significantly during the past century, largely because of damage to spawning habitat associated with timber harvest and agriculture in the watershed. In addition, approximately 20-25% of the then-remaining chum salmon spawning habitat was lost during a 1999 channel avulsion that destroyed an important artificial spawning channel operated by the Washington Department of Fish and Wildlife (WDFW). Although the lack of stable, high-quality spawning habitat is considered the primary physical limitation on Grays River chum salmon production today, few data are available to guide watershed management and channel restoration activities. The objectives of the Grays River Watershed and Biological Assessment project were to (1) perform a comprehensive watershed and biological analysis, including hydrologic, geomorphic, and ecological assessments; (2) develop a prioritized list of actions that protect and restore critical chum and Chinook salmon spawning habitat in the Grays River based on comprehensive geomorphic, hydrologic, and stream channel assessments; and (3) gain a better understanding of chum and Chinook salmon habitat requirements and survival within the lower Columbia River and the Grays River. The watershed-based approach to river ecosystem restoration relies on a conceptual framework that describes general relationships between natural landscape characteristics, watershed-scale habitat-forming processes, aquatic

  5. Determination of the Biologically Relevant Sampling Depth for Terrestrial and Aquatic Ecological Risk Assessments (Final Report)

    Science.gov (United States)

    This technical paper provides defensible approximations for what the depth of the biologically active zone, or “biotic zone” is within certain environments. The methods used in this study differ somewhat between Part 1 (Terrestrial Biotic Zone) and Part 2 (Aquatic Biotic Zone). ...

  6. Biology Reflective Assessment Curriculum

    Science.gov (United States)

    Bayley, Cheryl Ann

    Often students and educators view assessments as an obligation and finality for a unit. In the current climate of high-stakes testing and accountability, the balance of time, resources and emphasis on students' scores related to assessment have been slanted considerably toward the summative side. This tension between assessment for accountability and assessment to inform teaching strains instruction and educators' ability to use that information to design learning opportunities that help students develop deeper conceptual understanding. A substantive body of research indicates that formative and reflective assessment can significantly improve student learning. Biology Reflective Assessment Curriculum (BRAC) examines support provided for high school science students through assessment practices. This investigation incorporates the usage of reflective assessments as a guiding practice for differentiated instruction and student choice. Reflective assessment is a metacognitive strategy that promotes self-monitoring and evaluation. The goals of the curriculum are to promote self-efficacy and conceptual understanding in students learning biology through developing their metacognitive awareness. BRAC was implemented in a high school biology classroom. Data from assessments, metacognitive surveys, self-efficacy surveys, reflective journals, student work, a culminating task and field notes were used to evaluate the effectiveness of the curriculum. The results suggest that students who develop their metacognitive skills developed a deeper conceptual understanding and improved feelings of self-efficacy when they were engaged in a reflective assessment unit embedded with student choice. BRAC is a tool for teachers to use assessments to assist students in becoming metacognitive and to guide student choice in learning opportunities.

  7. Compilation and assessment of microwave bioeffects. Final report. A selective review of the literature on biological effects of microwaves in relation to the Satellite Power System (SPS)

    Energy Technology Data Exchange (ETDEWEB)

    Justesen, D.R.; Ragan, H.A.; Rogers, L.E.; Guy, A.W.; Hjeresen, D.L.; Hinds, W.T.; Phillips, R.D.

    1978-05-01

    One of many alternate sources of electrical energy that are being considered by the Department of Energy is a microwave-mediated Satellite Power System (SPS). Once inserted into geosynchronous orbit at an altitude of more than 40,000 kilometers, a satellite would collect then convert the sun's energy to 2450-MHz microwaves, which would be beamed to the Earth's surface, where a rectifying antenna (rectenna) would convert the microwaves to electrical current suitable for industrial and domestic use. The expanse of each rectenna (about 10 by 13 kilometers), the power density of the continuous-wave microwave beam (approx. 23 mW/cm/sup 2/ at center, with fall off to 1 mW/cm/sup 2/ or less at the periphery of the rectenna), and the possibility that 20 or more satellite systems will eventually be operating, creates two sets of interrelated problems for biological/ecological assessment. These are 1) the effects of microwave fields of higher intensity on airborne biota (including human beings in aircraft) that may traffic the area above the rectenna and 2) the effects of virtually perpetual fields of much lower intensity on all forms of life at and beyond the rectennae's zone of exclusion. In this review, the scientific literature is examined, not only for biological effects that are pertinent to assessment of SPS, but for hiatuses of knowledge that will have to be filled before SPS can be vouched for operational safety.

  8. 25 CFR 575.9 - Final assessment.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Final assessment. 575.9 Section 575.9 Indians NATIONAL... § 575.9 Final assessment. (a) If the respondent fails to request a hearing as provided in part 577 of this chapter, the proposed civil fine assessment shall become a final order of the Commission....

  9. Compilation and assessment of microwave bioeffects. Final report. A selective review of the literature on biological effects of microwaves in relation to the satellite power system

    Energy Technology Data Exchange (ETDEWEB)

    Justesen, D. R.; Ragan, H. A.; Rogers, L. E.; Guy, A. W.; Hjeresen, D. L.; Hinds, W. T.

    1978-05-01

    Potential biological and ecological problems are the focus of a review of the world's scientific literature on biological effects of microwave radiation. The emphasis is on recently reported data and on the 2450-MHz continuous-wave (CW) radiation that is envisioned for a Satellite Power System (SPS).

  10. Biological monitoring of Upper Three Runs Creek, Savannah River Plant, Aiken County, South Carolina. Final report on macroinvertebrate stream assessments for F/H area ETF effluent discharge, July 1987--February 1990

    Energy Technology Data Exchange (ETDEWEB)

    Specht, W.L.

    1991-10-01

    In anticipation of the fall 1988 start up of effluent discharges into Upper Three Creek by the F/H Area Effluent Treatment Facility of the Savannah River Site, Aiken, SC, a two and one half year biological study was initiated in June 1987. Upper Three Runs Creek is an intensively studied fourth order stream known for its high species richness. Designed to assess the potential impact of F?H area effluent on the creek, the study includes qualitative and quantitative macroinvertebrate stream surveys at five sites, chronic toxicity testing of the effluent, water chemistry and bioaccumulation analysis. This final report presents the results of both pre-operational and post-operational qualitative and quantitative (artificial substrate) macroinvertebrate studies. Six quantitative and three qualitative studies were conducted prior to the initial release of the F/H ETF effluent and five quantitative and two qualitative studies were conducted post-operationally.

  11. Neutron interactions with biological tissue. Final report

    International Nuclear Information System (INIS)

    This program was aimed at creating a quantitative physical description, at the micrometer and nanometer levels, of the physical interactions of neutrons with tissue through the ejected secondary charged particles. The authors used theoretical calculations whose input includes neutron cross section data; range, stopping power, ion yield, and straggling information; and geometrical properties. Outputs are initial and slowing-down spectra of charged particles, kerma factors, average values of quality factors, microdosimetric spectra, and integral microdosimetric parameters such as bar yF, bar yD, y*. Since it has become apparent that nanometer site sizes are also relevant to radiobiological effects, the calculations of event size spectra and their parameters were extended to these smaller diameters. This information is basic to radiological physics, radiation biology, radiation protection of workers, and standards for neutron dose measurement

  12. Verbal Final Exam in Introductory Biology Yields Gains in Student Content Knowledge and Longitudinal Performance

    OpenAIRE

    Luckie, Douglas B.; Rivkin, Aaron M.; Aubry, Jacob R.; Marengo, Benjamin J.; Creech, Leah R.; Sweeder, Ryan D.

    2013-01-01

    We studied gains in student learning over eight semesters in which an introductory biology course curriculum was changed to include optional verbal final exams (VFs). Students could opt to demonstrate their mastery of course material via structured oral exams with the professor. In a quantitative assessment of cell biology content knowledge, students who passed the VF outscored their peers on the medical assessment test (MAT), an exam built with 40 Medical College Admissions Test (MCAT) quest...

  13. UC Merced Center for Computational Biology Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Colvin, Michael; Watanabe, Masakatsu

    2010-11-30

    Final report for the UC Merced Center for Computational Biology. The Center for Computational Biology (CCB) was established to support multidisciplinary scientific research and academic programs in computational biology at the new University of California campus in Merced. In 2003, the growing gap between biology research and education was documented in a report from the National Academy of Sciences, Bio2010 Transforming Undergraduate Education for Future Research Biologists. We believed that a new type of biological sciences undergraduate and graduate programs that emphasized biological concepts and considered biology as an information science would have a dramatic impact in enabling the transformation of biology. UC Merced as newest UC campus and the first new U.S. research university of the 21st century was ideally suited to adopt an alternate strategy - to create a new Biological Sciences majors and graduate group that incorporated the strong computational and mathematical vision articulated in the Bio2010 report. CCB aimed to leverage this strong commitment at UC Merced to develop a new educational program based on the principle of biology as a quantitative, model-driven science. Also we expected that the center would be enable the dissemination of computational biology course materials to other university and feeder institutions, and foster research projects that exemplify a mathematical and computations-based approach to the life sciences. As this report describes, the CCB has been successful in achieving these goals, and multidisciplinary computational biology is now an integral part of UC Merced undergraduate, graduate and research programs in the life sciences. The CCB began in fall 2004 with the aid of an award from U.S. Department of Energy (DOE), under its Genomes to Life program of support for the development of research and educational infrastructure in the modern biological sciences. This report to DOE describes the research and academic programs

  14. The Molecular Biology Capstone Assessment: A Concept Assessment for Upper-Division Molecular Biology Students

    Science.gov (United States)

    Couch, Brian A.; Wood, William B.; Knight, Jennifer K.

    2015-01-01

    Measuring students' conceptual understandings has become increasingly important to biology faculty members involved in evaluating and improving departmental programs. We developed the Molecular Biology Capstone Assessment (MBCA) to gauge comprehension of fundamental concepts in molecular and cell biology and the ability to apply these concepts in…

  15. 50 CFR 402.12 - Biological assessments.

    Science.gov (United States)

    2010-10-01

    ... issue. (3) A review of the literature and other information. (4) An analysis of the effects of the... biological assessment to the Director for review. The Director will respond in writing within 30 days as to... shall convey to the Director either (1) a written request for a list of any listed or proposed...

  16. UN-aided Project Passing Final Assessment

    Institute of Scientific and Technical Information of China (English)

    Wang Anfang

    1995-01-01

    @@ A number of projects funded by the United Nations Development Program passed final examination and assessment in April 1994.They are the well-completion technical center project of the Southwest Petroleum Institute with a fund of 1.27 million US dollars and the acidizing and fracturing technical service center of Wanzhuang Branch Research Institute of Petroleum Exploration and Development (RIPED) with a fund of 1.41 million US dollars.

  17. Nuclear Nonproliferation Ontology Assessment Team Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Strasburg, Jana D.; Hohimer, Ryan E.

    2012-01-01

    Final Report for the NA22 Simulations, Algorithm and Modeling (SAM) Ontology Assessment Team's efforts from FY09-FY11. The Ontology Assessment Team began in May 2009 and concluded in September 2011. During this two-year time frame, the Ontology Assessment team had two objectives: (1) Assessing the utility of knowledge representation and semantic technologies for addressing nuclear nonproliferation challenges; and (2) Developing ontological support tools that would provide a framework for integrating across the Simulation, Algorithm and Modeling (SAM) program. The SAM Program was going through a large assessment and strategic planning effort during this time and as a result, the relative importance of these two objectives changed, altering the focus of the Ontology Assessment Team. In the end, the team conducted an assessment of the state of art, created an annotated bibliography, and developed a series of ontological support tools, demonstrations and presentations. A total of more than 35 individuals from 12 different research institutions participated in the Ontology Assessment Team. These included subject matter experts in several nuclear nonproliferation-related domains as well as experts in semantic technologies. Despite the diverse backgrounds and perspectives, the Ontology Assessment team functioned very well together and aspects could serve as a model for future inter-laboratory collaborations and working groups. While the team encountered several challenges and learned many lessons along the way, the Ontology Assessment effort was ultimately a success that led to several multi-lab research projects and opened up a new area of scientific exploration within the Office of Nuclear Nonproliferation and Verification.

  18. Computational Tools to Assess Turbine Biological Performance

    Energy Technology Data Exchange (ETDEWEB)

    Richmond, Marshall C.; Serkowski, John A.; Rakowski, Cynthia L.; Strickler, Brad; Weisbeck, Molly; Dotson, Curtis L.

    2014-07-24

    Public Utility District No. 2 of Grant County (GCPUD) operates the Priest Rapids Dam (PRD), a hydroelectric facility on the Columbia River in Washington State. The dam contains 10 Kaplan-type turbine units that are now more than 50 years old. Plans are underway to refit these aging turbines with new runners. The Columbia River at PRD is a migratory pathway for several species of juvenile and adult salmonids, so passage of fish through the dam is a major consideration when upgrading the turbines. In this paper, a method for turbine biological performance assessment (BioPA) is demonstrated. Using this method, a suite of biological performance indicators is computed based on simulated data from a CFD model of a proposed turbine design. Each performance indicator is a measure of the probability of exposure to a certain dose of an injury mechanism. Using known relationships between the dose of an injury mechanism and frequency of injury (dose–response) from laboratory or field studies, the likelihood of fish injury for a turbine design can be computed from the performance indicator. By comparing the values of the indicators from proposed designs, the engineer can identify the more-promising alternatives. We present an application of the BioPA method for baseline risk assessment calculations for the existing Kaplan turbines at PRD that will be used as the minimum biological performance that a proposed new design must achieve.

  19. Mathematical modeling in biology: A critical assessment

    International Nuclear Information System (INIS)

    The molecular revolution and the development of biology-derived industry have led in the last fifty years to an unprecedented 'lead forward' of life sciences in terms of experimental data. Less success has been achieved in the organisation of such data and in the consequent development of adequate explanatory and predictive theories and models. After a brief historical excursus inborn difficulties of mathematisation of biological objects and processes derived from the complex dynamics of life are discussed along with the logical tools (simplifications, choice of observation points etc.) used to overcome them. 'Autistic', monodisciplinary attitudes towards biological modeling of mathematicians, physicists, biologists aimed in each case at the use of the tools of other disciplines to solve 'selfish' problems are also taken into account and a warning against derived dangers (reification of mono disciplinary metaphors, lack of falsification etc.) is given. Finally 'top.down' (deductive) and 'bottom up' (inductive) heuristic interactive approaches to mathematisation are critically discussed with the help of serie of examples

  20. Synthetic biology ethics: a deontological assessment.

    Science.gov (United States)

    Heavey, Patrick

    2013-10-01

    In this article I discuss the ethics of synthetic biology from a broadly deontological perspective, evaluating its morality in terms of the integrity of nature, the dignity of life and the relationship between God and his creation. Most ethical analyses to date have been largely consequentialist in nature; they reveal a dual use dilemma, showing that synbio has potential for great good and great evil, possibly more so than any step humanity has taken before. A deontological analysis may help to resolve this dilemma, by evaluating whether synbio is right or wrong in itself. I also assess whether deontology alone is a sufficient methodological paradigm for the proper evaluation of synbio ethics. PMID:24010856

  1. Final Environmental Assessment of Red River Establishment

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — No adverse biological impacts are anticipated and the public level of sportfishing, hunting, and wildlife observation is compatible with the scope and purpose of...

  2. Use of biological indicators in TMDL assessment and implementation

    OpenAIRE

    Yagow, G.; Wilson, B.; Srivastava, P; Obropta, C. C.

    2006-01-01

    Most states in the U.S. have a general water quality standard intended to protect water from all potential pollutants not specifically named or identified in other standards. Biological indicators are used, in part, to assess the level of water quality with respect to this general standard. Under EPA's Total Maximum Daily Load (TMDL) program, impaired waters based on a biological assessment require an additional step compared with non-biological TMDLs. In non-biological TMDLs, the "pollutant"...

  3. COMPILATION AND ASSESSMENT OF MICROWAVE BIOEFFECTS AO-02-0l/EA81028 FINAL REPORT A SELECTIVE REVIEW OF THE LITERATURE ON BIOLOGICAL EFFECTS OF MICROWAVES IN RELATION TO THE SATELLITE POWER SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    DR. Justesen, HA. Ragan, LE. Rogers, AW. Guy, DL. Hjeresen, WT. Hinds, RD. Phillips, Project Manager

    1978-05-01

    Potential biological and ecological problems are the focus of a review of the world's scientific literature on biological effects of microwave radiation. The emphasis is on recently reported data and on the 2450-MHz continuous-wave (CW) radiation that is envisioned for a Satellite Power System (SPS).

  4. Molecular biological enhancement of coal biodesulfurization. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Litchfield, J.H.; Zupancic, T.J.; Kittle, J.D. Jr.; Baker, B.; Palmer, D.T.; Traunero, C.G.; Wyza, R.E.; Schweitzer, A.; Conkle, H.N. [Battelle, Columbus, OH (United States); Chakravarty, L.; Tuovinen, O.H. [Ohio State Univ., Columbus, OH (United States)

    1992-10-08

    Progress is reported in understanding Thiobacillus molecular biology, specifically in the area of vector development. At the initiation of this program, the basic elements needed for performing genetic engineering in T. ferrooxidans were either not yet developed. Improved techniques are described which will make it easier to construct and analyze the genetic structure and metabolism of recombinant T. ferrooxidans. The metabolism of the model organic sulfur compound dibenzothiophene (DBT) by certain heterotrophic bacteria was confirmed and characterized. Techniques were developed to analyze the metabolites of DBT, so that individual 4S pathway metabolites could be distinguished. These techniques are expected to be valuable when engineering organic sulfur metabolism in Thiobacillus. Strain isolation techniques were used to develop pure cultures of T. ferrooxidans seven of which were assessed as potential recombinant hosts. The mixotrophic strain T. coprinus was also characterized for potential use as an electroporation host. A family of related Thiobacillus plasmids was discovered in the seven strains of P. ferrooxidans mentioned above. One of these plasmids, pTFI91, was cloned into a pUC-based plasmid vector, allowing it to propagate in E. coli. A key portion of the cloned plasmid was sequenced. This segment, which is conserved in all of the related plasmids characterized, contains the vegetative origin of DNA replication, and fortuitously, a novel insertion sequence, designated IS3091. The sequence of the DNA origin revealed that these Thiobacillus plasmids represent a unique class of replicons not previously described. The potentially useful insertion sequence IS3091 was identified as a new member of a previously undefined family of insertion sequences which include the E. coli element IS30.

  5. River Protection Project information systems assessment; FINAL

    International Nuclear Information System (INIS)

    The Information Systems Assessment Report documents the results from assessing the Project Hanford Management Contract (PHMC) Hanford Data Integrator 2000 (HANDI 2000) system, Business Management System (BMS) and Work Management System phases (WMS), with respect to the System Engineering Capability Assessment Model (CAM). The assessment was performed in accordance with the expectations stated in the fiscal year (FY) 1999 Performance Agreement 7.1.1, item (2) which reads, ''Provide an assessment report on the selected Integrated Information System by July 31, 1999.'' This report assesses the BMS and WMS as implemented and planned for the River Protection Project (RPP). The systems implementation is being performed under the PHMC HANDI 2000 information system project. The project began in FY 1998 with the BMS, proceeded in FY 1999 with the Master Equipment List portion of the WMS, and will continue the WMS implementation as funding provides. This report constitutes an interim quality assessment providing information necessary for planning RPP's information systems activities. To avoid confusion, HANDI 2000 will be used when referring to the entire system, encompassing both the BMS and WMS. A graphical depiction of the system is shown in Figure 2-1 of this report

  6. A Diagnostic Assessment for Introductory Molecular and Cell Biology

    Science.gov (United States)

    Shi, Jia; Wood, William B.; Martin, Jennifer M.; Guild, Nancy A.; Vicens, Quentin; Knight, Jennifer K.

    2010-01-01

    We have developed and validated a tool for assessing understanding of a selection of fundamental concepts and basic knowledge in undergraduate introductory molecular and cell biology, focusing on areas in which students often have misconceptions. This multiple-choice Introductory Molecular and Cell Biology Assessment (IMCA) instrument is designed…

  7. Assessment and management of biosafety in synthetic biology

    OpenAIRE

    Zhengjun Guan; Lei Pei; Markus Schmidt; Wei Wei

    2012-01-01

    While having developed into one of the most dynamic fields of the life sciences, synthetic biology may pose potential risks to the environment and human health. Based on current national and international risk assessment methods and current regulation of synthetic biology, we reviewed risk assessment in relation to synthetic biology’s research subfields (such as DNA-based biocircuits, minimal genome, protocells and chemical synthetic biology), its relation with biosafety engineering, its effe...

  8. Biologic markers in risk assessment for environmental carcinogens

    OpenAIRE

    Perera, F.; Mayer, J.; Santella, R. M.; Brenner, D; Jeffrey, A.; Latriano, L; Smith, S.; Warburton, D; Young, T. L.; Tsai, W. Y.; Hemminki, K; Brandt-Rauf, P

    1991-01-01

    The potential of biologic markers to provide more timely and precise risk assessments for environmental carcinogens is viewed against the current state-of-the-art in biological monitoring/molecular epidemiology. Biologic markers such as carcinogen-DNA adducts and oncogene activation are currently considered valid qualitative indicators of potential risk, but for most chemical exposures research is needed to establish their validity as quantitative predictors of cancer risk. Biologic markers h...

  9. Minidoka Dam Wildlife Impact Assessment: Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Robert C.; Meuleman, G. Allyn

    1989-03-01

    A wildlife impact assessment has been developed for the US Bureau of Reclamation's Minidoka Dam and Reservoir in south central Idaho. This assessment was conducted to fulfill requirements of the Fish and Wildlife Program. Specific objectives of this study included the following: select target wildlife species, and identify their current status and management goals; estimate the net effects on target wildlife species resulting from hydroelectric development and operation; recommend protection, mitigation, and enhancement goals for target wildlife species affected by hydroelectric development and operation; and consult and coordinate impact assessment activities with the Northwest Power Planning Council, Bonneville Power Administration, US Bureau of Reclamation, Bureau of Land Management, Shoshone-Bannock Tribes, US Fish and Wildlife Service, Pacific Northwest Utilities Conference Committee, and other entities expressing interest in the project. 62 refs., 2 figs., 11 tabs.

  10. Final characterization report for the 108-F Biological Laboratory

    International Nuclear Information System (INIS)

    This report provides a compilation of characterization data for the 108-F Biological Laboratory collected during the period of May 7, 1996 through August 29, 1996. The 108-F Biology Laboratory is located on the Hanford Site in Richland, Washington. The characterization activities were organized and implemented to evaluate the radiological status of the laboratory and to identify hazardous materials. This report reflects the current conditions and status of the laboratory. Information in this report is intended to be utilized to prepare an accurate cost estimate for building demolition, to aid in planning decontamination and demolition activities, and allow proper disposal of demolition debris

  11. Geothermal resources assessment in Hawaii. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, D.M.

    1984-02-21

    The Hawaii Geothermal Resources Assessment Program was initiated in 1978. The preliminary phase of this effort identified 20 Potential Geothermal Resource Areas (PGRA's) using available geological, geochemical and geophysical data. The second phase of the Assessment Program undertook a series of field studies, utilizing a variety of geothermal exploration techniques, in an effort to confirm the presence of thermal anomalies in the identified PGRA's and, if confirmed, to more completely characterize them. A total of 15 PGRA's on four of the five major islands in the Hawaiian chain were subject to at least a preliminary field analysis. The remaining five were not considered to have sufficient resource potential to warrant study under the personnel and budget constraints of the program.

  12. Biologic markers in risk assessment for environmental carcinogens

    Energy Technology Data Exchange (ETDEWEB)

    Perera, F.; Mayer, J.; Santella, R.M.; Brenner, D.; Jeffrey, A.; Latriano, L.; Smith, S.; Warburton, D.; Young, T.L.; Tsai, W.Y.; Brandt-Rauf, P. (Columbia Univ. School of Public Health, New York, NY (United States)); Hemminki, K. (Finnish School of Occupational Health, Helsinki (Finland))

    1991-01-01

    The potential of biologic markers to provide more timely and precise risk assessments for environmental carcinogens is viewed against the current state-of-the-art in biological monitoring/molecular epidemiology. Biologic markers such as carcinogen-DNA adducts and oncogene activation are currently considered valid qualitative indicators of potential risk, but for most chemical exposures research is needed to establish their validity as quantitative predictors of cancer risk. Biologic markers have, however, already provided valuable insights into the magnitude of interindividual variation in response to carcinogenic exposures, with major implications for risk assessment.

  13. Biologic markers in risk assessment for environmental carcinogens

    International Nuclear Information System (INIS)

    The potential of biologic markers to provide more timely and precise risk assessments for environmental carcinogens is viewed against the current state-of-the-art in biological monitoring/molecular epidemiology. Biologic markers such as carcinogen-DNA adducts and oncogene activation are currently considered valid qualitative indicators of potential risk, but for most chemical exposures research is needed to establish their validity as quantitative predictors of cancer risk. Biologic markers have, however, already provided valuable insights into the magnitude of interindividual variation in response to carcinogenic exposures, with major implications for risk assessment

  14. NANA Geothermal Assessment Program Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Jay Hermanson

    2010-06-22

    In 2008, NANA Regional Corporation (NRC) assessed geothermal energy potential in the NANA region for both heat and/or electricity production. The Geothermal Assessment Project (GAP) was a systematic process that looked at community resources and the community's capacity and desire to develop these resources. In October 2007, the US Department of Energy's Tribal Energy Program awarded grant DE-FG36-07GO17075 to NRC for the GAP studies. Two moderately remote sites in the NANA region were judged to have the most potential for geothermal development: (1) Granite Mountain, about 40 miles south of Buckland, and (2) the Division Hot Springs area in the Purcell Mountains, about 40 miles south of Shungnak and Kobuk. Data were collected on-site at Granite Mountain Hot Springs in September 2009, and at Division Hot Springs in April 2010. Although both target geothermal areas could be further investigated with a variety of exploration techniques such as a remote sensing study, a soil geochemical study, or ground-based geophysical surveys, it was recommended that on-site or direct heat use development options are more attractive at this time, rather than investigations aimed more at electric power generation.

  15. Thermionic conversion reactor technology assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1984-02-01

    The in-core thermionic space nuclear power supply may be the only identified reactor-power concept that can meet the SP-100 size functional requirements with demonstrated state-of-the-art reactor system and space-qualified power system component temperatures. The SP-100 configuration limits provide a net 40 m/sup 2/ of primary non-deployed radiator area. If a reasonable 7-year degradation allowance of 15% to 20% is provided then the beginning of life (BOL) net power output requirement is about 120 kWe. Consequently, the SP-100 power system must produce a P/A of 2.7 kWe/m/sup 2/. This non-deployed radiator area power density performance can only be reasonably achieved by the thermionic in-core convertr system, the potassium Rankine turbine system and the Stirling engine system. The purpose of this study is to examine past and current tests and data, and to assess the potential for successful development of suitable fueled-thermionic converters that will meet SP-100 and growth requirements. The basis for the assessment will be provided and the recommended key developments plan set forth.

  16. Thermionic conversion reactor technology assessment. Final report

    International Nuclear Information System (INIS)

    The in-core thermionic space nuclear power supply may be the only identified reactor-power concept that can meet the SP-100 size functional requirements with demonstrated state-of-the-art reactor system and space-qualified power system component temperatures. The SP-100 configuration limits provide a net 40 m2 of primary non-deployed radiator area. If a reasonable 7-year degradation allowance of 15% to 20% is provided then the beginning of life (BOL) net power output requirement is about 120 kWe. Consequently, the SP-100 power system must produce a P/A of 2.7 kWe/m2. This non-deployed radiator area power density performance can only be reasonably achieved by the thermionic in-core convertr system, the potassium Rankine turbine system and the Stirling engine system. The purpose of this study is to examine past and current tests and data, and to assess the potential for successful development of suitable fueled-thermionic converters that will meet SP-100 and growth requirements. The basis for the assessment will be provided and the recommended key developments plan set forth

  17. Biological upgrading of coal-derived synthesis gas: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Barik, S.; Johnson, E.R.; Ko, C.W.; Clausen, E.C.; Gaddy, J.L.

    1986-10-01

    The technical feasibility of the biological conversion of coal synthesis gas to methane has been demonstrated in the University of Arkansas laboratories. Cultures of microorganisms have been developed which achieve total conversion in the water gas shift and methanation reactions in either mixed or pure cultures. These cultures carry out these conversions at ordinary temperatures and pressures, without sulfur toxicity. Several microorganisms have been identified as having commercial potential for producing methane. These include a mixed culture of unidentified bacteria; P. productus which produces acetate, a methane precursor; and Methanothrix sp., which produces methane from acetate. These cultures have been used in mixed reactors and immobilized cell reactors to achieve total CO and H/sub 2/ conversion in a retention time of less than two hours, quite good for a biological reactor. Preliminary economic projections indicate that a biological methanation plant with a size of 5 x 10/sup 10/ Btu/day can be economically attractive. 42 refs., 26 figs., 86 tabs.

  18. Final Environmental Assessment Ohio River Islands National Wildlife Refuge Proposal

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In this Final Environmental Assessment, the United States Fish and Wildlife Service describes various alternatives that could provide long-term protection to the...

  19. Complementary Safety Margin Assessment. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-10-15

    On March 11, 2011, a large part of the Japanese eastern coastal area was devastated by an earthquake, followed by an immense tsunami. As a result, thousands of people were killed, injured or made homeless. In the days that followed, the situation was further complicated because of the failing nuclear reactors on the Fukushima coast. The local environment suffered from radioactive releases, requiring evacuation zones, and generating international concerns about nuclear safety. In the wake of this disaster the European Union decided to assess safety on all operating nuclear reactors in its member states. This safety evaluation initiated by the European Union focusses on extreme natural hazards, beyond the standard safety evaluations which regularly have to be performed to demonstrate the safety of a nuclear power plant. Consequences of these extreme hazards for the Borssele NPP have been evaluated based on available safety analyses, supplemented by engineering judgement. In this way, the robustness of the existing plant has been assessed and possible measures to further increase the safety margins have been identified. This document presents the results of the Complementary Safety margin Assessment (CSA) performed for the NPP Borssele. The distinct difference between this report and former risk analysis reports in general and the existing Safety Report of the NPP Borssele is that the maximum resistance of the plant against redefined and more challenging events has been investigated, whereas traditionally the plant design is investigated against certain events that are determined on a historical basis. This different approach requires different analyses and studies, which in turn presents new insights into the robustness of the plant. This document has been prepared in the short time period between June 1 and October 31, 2011. If more time had been granted for this study, some of the subjects could have been pursued in greater depth. The EPZ project team has been

  20. 78 FR 46905 - Tobacco Transition Program; Final Assessment Procedures

    Science.gov (United States)

    2013-08-02

    ... information about the final quarterly assessments for the Tobacco Transition Program (TTP). Through the Tobacco Transition Payment Program (TTPP), which is part of the TTP, eligible former tobacco quota holders..., 2014. Also, as specified in the TTP regulations, the final two calendar quarterly payments are both...

  1. Boise geothermal injection well: Final environmental assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    The City of Boise, Idaho, an Idaho Municipal Corporation, is proposing to construct a well with which to inject spent geothermal water from its hot water heating system back into the geothermal aquifer. Because of a cooperative agreement between the City and the US Department of Energy to design and construct the proposed well, compliance to the National Environmental Policy Act (NEPA) is required. Therefore, this Environmental Assessment (EA) represents the analysis of the proposed project required under NEPA. The intent of this EA is to: (1) briefly describe historical uses of the Boise Geothermal Aquifer; (2) discuss the underlying reason for the proposed action; (3) describe alternatives considered, including the No Action Alternative and the Preferred Alternative; and (4) present potential environmental impacts of the proposed action and the analysis of those impacts as they apply to the respective alternatives.

  2. Klickitat Cogeneration Project: Final environmental assessment

    International Nuclear Information System (INIS)

    To meet BPA's contractual obligation to supply electrical power to its customers, BPA proposes to acquire power generated by Klickitat Cogeneration Project. BPA has prepared an environmental assessment evaluating the proposed project. Based on the EA analysis, BPA's proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 for the following reasons: (1)it will not have a significant impact land use, upland vegetation, wetlands, water quality, geology, soils, public health and safety, visual quality, historical and cultural resources, recreation and socioeconomics, and (2) impacts to fisheries, wildlife resources, air quality, and noise will be temporary, minor, or sufficiently offset by mitigation. Therefore, the preparation of an environmental impact statement is not required and BPA is issuing this FONSI (Finding of No Significant Impact)

  3. Boise geothermal injection well: Final environmental assessment

    International Nuclear Information System (INIS)

    The City of Boise, Idaho, an Idaho Municipal Corporation, is proposing to construct a well with which to inject spent geothermal water from its hot water heating system back into the geothermal aquifer. Because of a cooperative agreement between the City and the US Department of Energy to design and construct the proposed well, compliance to the National Environmental Policy Act (NEPA) is required. Therefore, this Environmental Assessment (EA) represents the analysis of the proposed project required under NEPA. The intent of this EA is to: (1) briefly describe historical uses of the Boise Geothermal Aquifer; (2) discuss the underlying reason for the proposed action; (3) describe alternatives considered, including the No Action Alternative and the Preferred Alternative; and (4) present potential environmental impacts of the proposed action and the analysis of those impacts as they apply to the respective alternatives

  4. Klickitat Cogeneration Project : Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration; Klickitat Energy Partners

    1994-09-01

    To meet BPA`s contractual obligation to supply electrical power to its customers, BPA proposes to acquire power generated by Klickitat Cogeneration Project. BPA has prepared an environmental assessment evaluating the proposed project. Based on the EA analysis, BPA`s proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 for the following reasons: (1)it will not have a significant impact land use, upland vegetation, wetlands, water quality, geology, soils, public health and safety, visual quality, historical and cultural resources, recreation and socioeconomics, and (2) impacts to fisheries, wildlife resources, air quality, and noise will be temporary, minor, or sufficiently offset by mitigation. Therefore, the preparation of an environmental impact statement is not required and BPA is issuing this FONSI (Finding of No Significant Impact).

  5. 77 FR 15121 - Final Land Protection Plan and Final Environmental Assessment for Everglades Headwaters National...

    Science.gov (United States)

    2012-03-14

    ... September 8, 2011, we published a Federal Register notice (76 FR 55699) announcing the proposed... published a Federal Register notice (76 FR 66321) announcing the extension of the comment deadline to... Fish and Wildlife Service Final Land Protection Plan and Final Environmental Assessment for...

  6. Biological control of Aleutian Island arctic fox: Final report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Empirical and literature data on the resource utilization patterns of arctic fox (Alopex lagopus) and red fox (Vulpes vulpes) are evaluated to assess the potential...

  7. NANA Wind Resource Assessment Program Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Jay Hermanson

    2010-09-23

    NANA Regional Corporation (NRC) of northwest Alaska is located in an area with abundant wind energy resources. In 2007, NRC was awarded grant DE-FG36-07GO17076 by the US Department of Energy's Tribal Energy Program for funding a Wind Resource Assessment Project (WRAP) for the NANA region. The NANA region, including Kotzebue Electric Association (KEA) and Alaska Village Electric Cooperative (AVEC) have been national leaders at developing, designing, building, and operating wind-diesel hybrid systems in Kotzebue (starting in 1996) and Selawik (2002). Promising sites for the development of new wind energy projects in the region have been identified by the WRAP, including Buckland, Deering, and the Kivalina/Red Dog Mine Port Area. Ambler, Shungnak, Kobuk, Kiana, Noorvik & Noatak were determined to have poor wind resources at sites in or very near each community. However, all five of these communities may have better wind resources atop hills or at sites with slightly higher elevations several miles away.

  8. Final rapid reactivation project environmental assessment

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) has prepared an environmental assessment (EA) for the Rapid Reactivation Project at Sandia National Laboratories, New Mexico. The EA analyzes the potential effects of a proposal to increase production of neutron generators from the current capability of 600 units per year up to 2,000 units per year. The project would use existing buildings and infrastructure to the maximum extent possible to meet the additional production needs. The increased production levels would necessitate modifications and additions involving a total area of approximately 26,290 gross square feet at Sandia National Laboratories, New Mexico, Technical Area 1. Additional production equipment would be procured and installed. The no-action alternative would be to continue production activities at the current capability of 600 units per year. The EA analyzes effects on health, safety, and air quality, resulting from construction and operation and associated cumulative effects. A detailed description of the proposed action and its environmental consequences is presented in the EA

  9. Security Assessment Simulation Toolkit (SAST) Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Meitzler, Wayne D.; Ouderkirk, Steven J.; Hughes, Chad O.

    2009-11-15

    The Department of Defense Technical Support Working Group (DoD TSWG) investment in the Pacific Northwest National Laboratory (PNNL) Security Assessment Simulation Toolkit (SAST) research planted a technology seed that germinated into a suite of follow-on Research and Development (R&D) projects culminating in software that is used by multiple DoD organizations. The DoD TSWG technology transfer goal for SAST is already in progress. The Defense Information Systems Agency (DISA), the Defense-wide Information Assurance Program (DIAP), the Marine Corps, Office Of Naval Research (ONR) National Center For Advanced Secure Systems Research (NCASSR) and Office Of Secretary Of Defense International Exercise Program (OSD NII) are currently investing to take SAST to the next level. PNNL currently distributes the software to over 6 government organizations and 30 DoD users. For the past five DoD wide Bulwark Defender exercises, the adoption of this new technology created an expanding role for SAST. In 2009, SAST was also used in the OSD NII International Exercise and is currently scheduled for use in 2010.

  10. Bigheaded carps : a biological synopsis and environmental risk assessment

    Science.gov (United States)

    Kolar, Cindy S.; Chapman, Duane C.; Courtenay, Walter R., Jr.; Housel, Christine M.; Williams, James D.; Jennings, Dawn P.

    2007-01-01

    The book is a detailed risk assessment and biological synopsis of the bigheaded carps of the genus Hypophthalmichthys, which includes the bighead, silver, and largescale silver carps. It summarizes the scientific literature describing their biology, ecology, uses, ecological effects, and risks to the environment.

  11. Scientific Opinion on Risk Assessment of Synthetic Biology.

    Science.gov (United States)

    Epstein, Michelle M; Vermeire, Theo

    2016-08-01

    In 2013, three Scientific Committees of the European Commission (EC) drafted Scientific Opinions on synthetic biology that provide an operational definition and address risk assessment methodology, safety aspects, environmental risks, knowledge gaps, and research priorities. These Opinions contribute to the international discussions on the risk governance for synthetic biology developments.

  12. Scientific Opinion on Risk Assessment of Synthetic Biology.

    Science.gov (United States)

    Epstein, Michelle M; Vermeire, Theo

    2016-08-01

    In 2013, three Scientific Committees of the European Commission (EC) drafted Scientific Opinions on synthetic biology that provide an operational definition and address risk assessment methodology, safety aspects, environmental risks, knowledge gaps, and research priorities. These Opinions contribute to the international discussions on the risk governance for synthetic biology developments. PMID:27234301

  13. Support of the IMA summer program molecular biology. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Friedman, A.

    1995-08-01

    The revolutionary progress in molecular biology within the last 30 years opens the way to full understanding of the molecular structures and mechanisms of living organisms. The mathematical sciences accompany and support much of the progress achieved by experiment and computation, as well as provide insight into geometric and topological properties of biomolecular structure and processes. The 4 week program at the IMA brought together biologists and mathematicians leading researchers, postdocs, and graduate students. It focused on genetic mapping and DNA sequencing, followed by biomolecular structure and dynamics. High-resolution linkage maps of genetic marker were discussed extensively in relation to the human genome project. The next level of DNA mapping is physical mapping, consisting of overlapping clones spanning the genome. These maps are extremely useful for genetic analysis. They provide the material for less redundant sequencing and for detailed searches for a gene among other things. This topic was also extensively studied by the participants. From there, the program moved to consider protein structure and dynamics; this is a broad field with a large array of interesting topics. It is of key importance in answering basic scientific questions about the nature of all living organisms, and has practical biomedical applications. The major subareas of structure prediction and classification, techniques and heuristics for the simulation of protein folding, and molecular dynamics provide a rich problem domain where mathematics can be helpful in analysis, modeling, and simulation. One of the important problems in molecular biology is the three-dimensional structure of proteins, DNA and RNA in the cell, and the relationship between structure and function. The program helped increased the understanding of the topology of cellular DNA, RNA and proteins and the various life-sustaining mechanisms used by the cell which modify this molecular topology.

  14. Biological production of ethanol from coal. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-01

    Due to the abundant supply of coal in the United States, significant research efforts have occurred over the past 15 years concerning the conversion of coal to liquid fuels. Researchers at the University of Arkansas have concentrated on a biological approach to coal liquefaction, starting with coal-derived synthesis gas as the raw material. Synthesis gas, a mixture of CO, H{sub 2}, CO{sub 2}, CH{sub 4} and sulfur gases, is first produced using traditional gasification techniques. The CO, CO{sub 2} and H{sub 2} are then converted to ethanol using a bacterial culture of Clostridium 1jungdahlii. Ethanol is the desired product if the resultant product stream is to be used as a liquid fuel. However, under normal operating conditions, the ``wild strain`` produces acetate in favor of ethanol in conjunction with growth in a 20:1 molar ratio. Research was performed to determine the conditions necessary to maximize not only the ratio of ethanol to acetate, but also to maximize the concentration of ethanol resulting in the product stream.

  15. FY05 LDRD Final Report, A Revolution in Biological Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, H N; Bajt, S; Balhorn, R; Barty, A; Barsky, D; Bogan, M; Chung, S; Frank, M; Hau-Riege, S; Ishii, H; London, R; Marchesini, S; Noy, A; Segelke, B; Szoke, A; Szoke, H; Trebes, J; Wootton, A; Hajdu, J; Bergh, M; Caleman, C; Huldt, G; Lejon, S; der Spoel, D v; Howells, M; He, H; Spence, J; Nugent, K; Ingerman, E

    2006-01-20

    X-ray free-electron lasers (XFELs) are currently under development and will provide a peak brightness more than 10 orders of magnitude higher than modern synchrotrons. The goal of this project was to perform the fundamental research to evaluate the possibility of harnessing these unique x-ray sources to image single biological particles and molecules at atomic resolution. Using a combination of computational modeling and experimental verification where possible, they showed that it should indeed be possible to record coherent scattering patterns from single molecules with pulses that are shorter than the timescales for the degradation of the structure due to the interaction with those pulses. They used these models to determine the effectiveness of strategies to allow imaging using longer XFEL pulses and to design validation experiments to be carried out at interim ultrafast sources. They also developed and demonstrated methods to recover three-dimensional (3D) images from coherent diffraction patterns, similar to those expected from XFELs. The images of micron-sized test objects are the highest-resolution 3D images of any noncrystalline material ever formed with x-rays. The project resulted in 14 publications in peer-reviewed journals and four records of invention.

  16. Dosimetry using environmental and biological materials. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Haskell, E.; Kenner, G.; Hayes, R.

    1996-09-01

    Although theoretical models have been the traditional tool for assessment of doses delivered by nuclear accidents, their use is now accompanied by increasing political and scientific demand for physical measurements which provide site specific dose information related directly to the original events, can be used to verify and augment the theoretical models, and can be performed and reflicated by independent laboratories. This report details a four year effort to improve the sensitivity and reliability of retrospective methods, to collaborate with laboratories engaged in related research, and to share the technology with startup laboratories seeking similar capabilities.

  17. Assessing Practical Laboratory Skills in Undergraduate Molecular Biology Courses

    Science.gov (United States)

    Hunt, Lynne; Koenders, Annette; Gynnild, Vidar

    2012-01-01

    This study explored a new strategy of assessing laboratory skills in a molecular biology course to improve: student effort in preparation for and participation in laboratory work; valid evaluation of learning outcomes; and students' employment prospects through provision of evidence of their skills. Previously, assessment was based on written…

  18. Final Report on Pilot Studies / Final Report on Classroom Research with STEM and TESL Assessment

    DEFF Research Database (Denmark)

    Biel, Carmen; Wake, Jo Dugstad; Hesse, Friedrich;

    This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables.......This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables....

  19. The development and assessment of biological treatments for children.

    Science.gov (United States)

    Smith, Eve M D; Foster, Helen E; Beresford, Michael W

    2015-03-01

    The development of biological agents with specific immunological targets has revolutionized the treatment of a wide variety of paediatric diseases where traditional immunosuppressive agents have been partly ineffective or intolerable. The increasing requirement for pharmaceutical companies to undertake paediatric studies has provided impetus for studies of biologics in children. The assessment of biological agents in children to date has largely relied upon randomized controlled trials using a withdrawal design, rather than a parallel study design. This approach has been largely used due to ethical concerns, including use of placebo treatments in children with active chronic disease, and justified on the basis that treatments have usually already undergone robust assessment in related adult conditions. However, this study design limits the reliability of the data and can confuse the interpretation of safety results. Careful ongoing monitoring of safety and efficacy in real-world practice through national and international biologics registries and robust reporting systems is crucial. The most commonly used biological agents in children target tumour necrosis factor-α, interleukin-1, interleukin-6 and cytotoxic lymphocyte-associated antigen-4. These agents are most frequently used in paediatric rheumatic diseases. This review discusses the development and assessment of biologics within paediatric rheumatology with reference to the lessons learned from use in other subspecialties. PMID:24750505

  20. Color image quality assessment with biologically inspired feature and machine learning

    Science.gov (United States)

    Deng, Cheng; Tao, Dacheng

    2010-07-01

    In this paper, we present a new no-reference quality assessment metric for color images by using biologically inspired features (BIFs) and machine learning. In this metric, we first adopt a biologically inspired model to mimic the visual cortex and represent a color image based on BIFs which unifies color units, intensity units and C1 units. Then, in order to reduce the complexity and benefit the classification, the high dimensional features are projected to a low dimensional representation with manifold learning. Finally, a multiclass classification process is performed on this new low dimensional representation of the image and the quality assessment is based on the learned classification result in order to respect the one of the human observers. Instead of computing a final note, our method classifies the quality according to the quality scale recommended by the ITU. The preliminary results show that the developed metric can achieve good quality evaluation performance.

  1. Biological dosimetry: chromosomal aberration analysis for dose assessment

    International Nuclear Information System (INIS)

    In view of the growing importance of chromosomal aberration analysis as a biological dosimeter, the present report provides a concise summary of the scientific background of the subject and a comprehensive source of information at the technical level. After a review of the basic principles of radiation dosimetry and radiation biology basic information on the biology of lymphocytes, the structure of chromosomes and the classification of chromosomal aberrations are presented. This is followed by a presentation of techniques for collecting blood, storing, transporting, culturing, making chromosomal preparations and scaring of aberrations. The physical and statistical parameters involved in dose assessment are discussed and examples of actual dose assessments taken from the scientific literature are given

  2. River Pollution: Part II. Biological Methods for Assessing Water Quality.

    Science.gov (United States)

    Openshaw, Peter

    1984-01-01

    Discusses methods used in the biological assessment of river quality and such indicators of clean and polluted waters as the Trent Biotic Index, Chandler Score System, and species diversity indexes. Includes a summary of a river classification scheme based on quality criteria related to water use. (JN)

  3. SILEX final ground testing and in-flight performance assessment

    Science.gov (United States)

    Planche, Gilles; Laurent, Bernard; Guillen, Jean-Claude; Chorvalli, V.; Desplats, Eric

    1999-04-01

    SILEX (Semi-Conductor Inter-satellite Link EXperiment) consists of one optical terminal on-board the French LEO observation satellite SPOT 4, and another on-board the European GEO telecommunication satellite ARTEMIS. While the first part of the SILEX verification plan had been oriented towards verification at equipment and subsystem levels, the final stages have mainly been devoted to terminal and system (terminals coupling effects) verification. During this final stage, a thermal vacuum test was conducted in a class 100- cleanliness environment with optical ground support equipment of outstanding performances. The obtained tests results, used to determine software compensations and verify optical and static pointing performances, have been entered into overall system simulation models to finalize flight performances budgets. In addition, systems tests were performed on each terminal with respective partner simulator to validate system simulation models and assess link performances and robustness and to verify communication bit error rate.

  4. Advanced Level Biology Teachers' Attitudes towards Assessment and Their Engagement in Assessment for Learning

    Science.gov (United States)

    Bramwell-Lalor, Sharon; Rainford, Marcia

    2015-01-01

    This paper reports on a Mixed Methods study involving an investigation into the attitudes of advanced level biology teachers towards assessment and describes the teachers' experiences while being engaged in Assessment for Learning (AfL) practices such as sharing of learning objectives and peer- and self-assessment. Quantitative data were collected…

  5. Probabilistic risk assessment (PRA) reference document. Final report

    International Nuclear Information System (INIS)

    This document describes the current status of probabilistic risk assessment (PRA) as practiced in the nuclear reactor regulatory process. The PRA studies that have been completed or are under way are reviewed. The levels of maturity of the methodologies used in a PRA are discussed. Insights derived from PRAs are listed. The potential uses of PRA results for regulatory purposes are discussed. This document was issued for comment in February 1984 entitled Probabilistic Risk Assessment (PRA): Status Report and Guidance for Regulatory Application. The comments received on the draft have been considered for this final version of the report

  6. Levels of Biological Diversity: a Spatial Approach to Assessment Methods

    Directory of Open Access Journals (Sweden)

    ALEXANDRU-IONUŢ PETRIŞOR

    2008-01-01

    Full Text Available Biological diversity, interpreted as a variety of natural and man-dominated biological and ecological systems, plays an important role in assuring their stability and can be interpreted at different spatial scales, based on the hierarchical level of the system (biocoenose/ ecosystem, biome/complex of ecosystem, biosphere/ecosphere. Literature distinguishes six levels of biodiversity, namely alpha, beta, gamma, delta, epsilon, and omega. The current paper lists methodologies appropriate for assessing diversity at each of these levels, with a particular focus on regional diversity (gamma, delta, and epsilon diversities, i.e. CORINE land cover classification and the biogeographical regions of the European Union.

  7. Quantification for complex assessment: uncertainty estimation in final year project thesis assessment

    Science.gov (United States)

    Kim, Ho Sung

    2013-12-01

    A quantitative method for estimating an expected uncertainty (reliability and validity) in assessment results arising from the relativity between four variables, viz examiner's expertise, examinee's expertise achieved, assessment task difficulty and examinee's performance, was developed for the complex assessment applicable to final year project thesis assessment including peer assessment. A guide map can be generated by the method for finding expected uncertainties prior to the assessment implementation with a given set of variables. It employs a scale for visualisation of expertise levels, derivation of which is based on quantified clarities of mental images for levels of the examiner's expertise and the examinee's expertise achieved. To identify the relevant expertise areas that depend on the complexity in assessment format, a graphical continuum model was developed. The continuum model consists of assessment task, assessment standards and criterion for the transition towards the complex assessment owing to the relativity between implicitness and explicitness and is capable of identifying areas of expertise required for scale development.

  8. Static Heat Loads in the LHC Arc Cryostats: Final Assessment

    CERN Document Server

    Parma, V

    2010-01-01

    This note presents the final assessment of the static heat loads in the LHC arc cryostats, using different experimental methods during the first commissioning period in 2007. This assessment further develops and completes previous estimates made during the commissioning of sector 7_8 [1]. The estimate of the helium inventory, a prerequisite for the heat load calculation, is also presented. Heat loads to the cold mass are evaluated from the internal energy balance during natural as well as powered warm-ups of the helium baths in different subsector. The helium inventory is calculated from the internal energy balance during powered warm-ups and matched with previous assessments. Furthermore, heat loads to the thermal shield are estimated from the non-isothermal cooling of the supercritical helium in line E. The comparison of measured heat loads with previous estimates and with budgeted values is then presented, while their correlation with some important parameters like insulation vacuum pressure and some heat ...

  9. Final voluntary release assessment/corrective action report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-12

    The US Department of Energy, Carlsbad Area Office (DOE-CAO) has completed a voluntary release assessment sampling program at selected Solid Waste Management Units (SWMUs) at the Waste Isolation Pilot Plant (WIPP). This Voluntary Release Assessment/Corrective Action (RA/CA) report has been prepared for final submittal to the Environmental protection Agency (EPA) Region 6, Hazardous Waste Management Division and the New Mexico Environment Department (NMED) Hazardous and Radioactive Materials Bureau to describe the results of voluntary release assessment sampling and proposed corrective actions at the SWMU sites. The Voluntary RA/CA Program is intended to be the first phase in implementing the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) and corrective action process at the WIPP. Data generated as part of this sampling program are intended to update the RCRA Facility Assessment (RFA) for the WIPP (Assessment of Solid Waste Management Units at the Waste Isolation Pilot Plant), NMED/DOE/AIP 94/1. This Final Voluntary RA/CA Report documents the results of release assessment sampling at 11 SWMUs identified in the RFA. With this submittal, DOE formally requests a No Further Action determination for these SWMUs. Additionally, this report provides information to support DOE`s request for No Further Action at the Brinderson and Construction landfill SWMUs, and to support DOE`s request for approval of proposed corrective actions at three other SWMUs (the Badger Unit Drill Pad, the Cotton Baby Drill Pad, and the DOE-1 Drill Pad). This information is provided to document the results of the Voluntary RA/CA activities submitted to the EPA and NMED in August 1995.

  10. Zero-emission vehicle technology assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Woods, T.

    1995-08-01

    This is the final report in the Zero-Emission Vehicle (ZEV) Technology Assessment, performed for NYSERDA by Booz-Allen & Hamilton Inc. Booz-Allen wrote the final report, and performed the following tasks as part of the assessment: assembled a database of key ZEV organizations, their products or services, and plans; described the current state of ZEV technologies; identified barriers to widespread ZEV deployment and projected future ZEV technical capabilities; and estimated the cost of ZEVs from 1998 to 2004. Data for the ZEV Technology Assessment were obtained from several sources, including the following: existing ZEV industry publications and Booz-Allen files; major automotive original equipment manufacturers; independent electric vehicle manufacturers; battery developers and manufacturers; infrastructure and component developers and manufacturers; the U.S. Department of Energy, the California Air Resources Board, and other concerned government agencies; trade associations such as the Electric Power Research Institute and the Electric Transportation Coalition; and public and private consortia. These sources were contacted by phone, mail, or in person. Some site visits of manufacturers also were conducted. Where possible, raw data were analyzed by Booz-Allen staff and/or verified by independent sources. Performance data from standardized test cycles were used as much as possible.

  11. Phosphorus recycling potential assessment by a biological test applied to wastewater sludge.

    Science.gov (United States)

    Braak, Etienne; Auby, Sarah; Piveteau, Simon; Guilayn, Felipe; Daumer, Marie-Line

    2016-01-01

    Phosphorus (P) recycling as mineral fertilizer from wastewater activated sludge (WAS) depends on the amount that can be dissolved and separated from the organic matter before the final crystallization step. The aim of the biological phosphorus dissolution potential (BPDP) test developed here was to assess the maximum amount of P that could be biologically released from WAS prior that the liquid phase enters the recovery process. It was first developed for sludge combining enhanced biological phosphorus removal and iron chloride. Because carbohydrates are known to induce acidification during the first stage of anaerobic digestion, sucrose was used as a co-substrate. Best results were obtained after 24-48 h, without inoculum, with a sugar/sludge ratio of 0.5 gCOD/gVS and under strict anaerobic conditions. Up to 75% of the total phosphorus in sludge from a wastewater treatment plant combining enhanced biological phosphorus removal and iron chloride phosphorus removal could be dissolved. Finally, the test was applied to assess BPDP from different sludge using alum compounds for P removal. No dissolution was observed when alum polychloride was used and less than 20% when alum sulphate was used. In all the cases, comparison to chemical acidification showed that the biological process was a major contributor to P dissolution. The possibility to crystallize struvite was discussed from the composition of the liquids obtained. The BPDP will be used not only to assess the potential for phosphorus recycling from sludge, but also to study the influence of the co-substrates available for anaerobic digestion of sludge. PMID:26786893

  12. Final Safety Assessment of Coal Tar as Used in Cosmetics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    Coal Tar is a semisolid by-product obtained in the destructive distillation of bituminous coal, which functions in cosmetic products as a cosmetic biocide and denaturant-antidandruff agent is also listed as a function, but this is considered an over-the-counter (OTC) drug use. In 2002, Coal Tar was reported to the Food and Drug Administration (FDA) to be used in four formulations, all of which appear to be OTC drug products. Coal Tar is monographed by the FDA as Category I (safe and effective) OTC drug ingredient for use in the treatment of dandruff, seborrhoea, and psoriasis. Coal Tar is absorbed through the skin of animals and humans and is systemically distributed. Although the Cosmetic Ingredient Review (CIR) Expert Panel believes that Coal Tar use as an antidandruff ingredient in OTC drug preparations is adequately addressed by the FDA regulations, the Panel also believes that the appropriate concentration of use of Coal Tar in cosmetic formulations should be that level that does not have a biological effect in the user. Additional data needed to make a safety assessment include product types in which Coal Tar is used (other than as an OTC drug ingredient), use concentrations, and the maximum concentration that does not induce a biological effect in users.

  13. Technical and economic assessment of solar hybrid repowering. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-09-01

    Public Service Company of New Mexico (PNM) has performed a Technical and Economic Assessment of Solar Hybrid Repowering under funding by the Department of Energy (DOE), the Electric Power Research Institute (EPRI), Western Energy Supply and Transmission (WEST) Associates, and a number of southwestern utilities. Solar hybrid repowering involves placement of solar hardware adjacent to and connected to existing gas- and oil-fueled electric generation units to displace some of or all the fossil fuel normally used during daylight hours. The subject study assesses the technical economic viability of the solar hybrid repowering concept within the southwestern United States and the PNM system. This document is a final report on the study and its results. The study was divided into the six primary tasks to allow a systematic investigation of the concept: (1) market survey and cost/benefit analysis, (2) study unit selection, (3) conceptual design and cost estimates, (4) unit economic analysis, (5) program planning, future phases, and (6) program management. Reeves Station No. 2 at Albuquerque, New Mexico, was selected for repowering with a design goal of 50 percent (25 MWe). The solar system design is based on the 10 MW solar central receiver pilot plant preliminary design for Barstow, California. SAN--1608-4-2 contains the technical drawings. (WHK)

  14. Flammability Assessment Methodology Program Phase I: Final Report

    Energy Technology Data Exchange (ETDEWEB)

    C. A. Loehr; S. M. Djordjevic; K. J. Liekhus; M. J. Connolly

    1997-09-01

    The Flammability Assessment Methodology Program (FAMP) was established to investigate the flammability of gas mixtures found in transuranic (TRU) waste containers. The FAMP results provide a basis for increasing the permissible concentrations of flammable volatile organic compounds (VOCs) in TRU waste containers. The FAMP results will be used to modify the ''Safety Analysis Report for the TRUPACT-II Shipping Package'' (TRUPACT-II SARP) upon acceptance of the methodology by the Nuclear Regulatory Commission. Implementation of the methodology would substantially increase the number of drums that can be shipped to the Waste Isolation Pilot Plant (WIPP) without repackaging or treatment. Central to the program was experimental testing and modeling to predict the gas mixture lower explosive limit (MLEL) of gases observed in TRU waste containers. The experimental data supported selection of an MLEL model that was used in constructing screening limits for flammable VOC and flammable gas concentrations. The MLEL values predicted by the model for individual drums will be utilized to assess flammability for drums that do not meet the screening criteria. Finally, the predicted MLEL values will be used to derive acceptable gas generation rates, decay heat limits, and aspiration time requirements for drums that do not pass the screening limits. The results of the program demonstrate that an increased number of waste containers can be shipped to WIPP within the flammability safety envelope established in the TRUPACT-II SARP.

  15. The BIOSCI electronic newsgroup network for the biological sciences. Final report, October 1, 1992--June 30, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Kristofferson, D.; Mack, D.

    1996-10-01

    This is the final report for a DOE funded project on BIOSCI Electronic Newsgroup Network for the biological sciences. A usable network for scientific discussion, major announcements, problem solving, etc. has been created.

  16. Biological monitoring and environmental assessment in the Alligator Rivers Region

    International Nuclear Information System (INIS)

    Mining projects in the Alligator Rivers Region can accumulate excess volumes of water from the heavy rains of the annual Wet season. Such water contains naturally-occurring substances (heavy metals, radionuclides, suspended solids) at concentrations greater than those in adjacent streams and could pose an environmental risk if allowed to drain freely from a site. Because transport by surface waters dominates dispersion of mine-derived material, much of the research carried out at the Alligator Rivers Region Research Institute has been centred on aquatic ecosystems. While chemical analysis of waters can be used to measure concentrations of selected constituents, only biological monitoring can be used to assess effects on organisms, a crucial aspect of environmental protection

  17. Hellsgate Winter Range: Wildlife mitigation project. Final environmental assessment

    International Nuclear Information System (INIS)

    Bonneville Power Administration (BPA) proposes to fund the Hellsgate Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Colville Confederated Tribes and the Bureau of Indian Affairs (BIA). The proposed action would allow the sponsors to secure property and conduct wildlife management activities within the boundaries of the Colville Indian Reservation. This Final Environmental Assessment (EA) examines the potential environmental effects of acquiring and managing property for wildlife and wildlife habitat within a large project area. This area consists of several separated land parcels, of which 2,000 hectares (4,943 acres) have been purchased by BPA and an additional 4,640 hectares (11,466 acres) have been identified by the Colville Confederated Tribes for inclusion in the Project. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat that was adversely affected by the construction of Grand Coulee and Chief Joseph Dams and their reservoirs

  18. Blue Creek Winter Range: Wildlife Mitigation Project. Final environmental assessment

    International Nuclear Information System (INIS)

    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Agreement pertaining to the Blue Creek Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Spokane Tribe, Upper Columbia United Tribes, and the Bureau of Indian Affairs (BIA). If fully implemented, the proposed action would allow the sponsors to protect and enhance 2,631 habitat units of big game winter range and riparian shrub habitat on 2,185 hectares (5,400 acres) of Spokane Tribal trust lands, and to conduct long term wildlife management activities within the Spokane Indian Reservation project area. This Final Environmental Assessment (EA) examines the potential environmental effects of securing land and conducting wildlife habitat enhancement and long term management activities within the boundaries of the Spokane Indian Reservation. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat adversely affected by the construction of Grand Coulee Dam and its reservoir

  19. Hellsgate Winter Range : Wildlife Mitigation Project. Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1995-03-01

    Bonneville Power Administration (BPA) proposes to fund the Hellsgate Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Colville Confederated Tribes and the Bureau of Indian Affairs (BIA). The proposed action would allow the sponsors to secure property and conduct wildlife management activities within the boundaries of the Colville Indian Reservation. This Final Environmental Assessment (EA) examines the potential environmental effects of acquiring and managing property for wildlife and wildlife habitat within a large project area. This area consists of several separated land parcels, of which 2,000 hectares (4,943 acres) have been purchased by BPA and an additional 4,640 hectares (11,466 acres) have been identified by the Colville Confederated Tribes for inclusion in the Project. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat that was adversely affected by the construction of Grand Coulee and Chief Joseph Dams and their reservoirs.

  20. Blue Creek Winter Range : Wildlife Mitigation Project : Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration; United States. Bureau of Indian Affairs; Spokane Tribe of the Spokane Reservation, Washington

    1994-11-01

    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Agreement pertaining to the Blue Creek Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Spokane Tribe, Upper Columbia United Tribes, and the Bureau of Indian Affairs (BIA). If fully implemented, the proposed action would allow the sponsors to protect and enhance 2,631 habitat units of big game winter range and riparian shrub habitat on 2,185 hectares (5,400 acres) of Spokane Tribal trust lands, and to conduct long term wildlife management activities within the Spokane Indian Reservation project area. This Final Environmental Assessment (EA) examines the potential environmental effects of securing land and conducting wildlife habitat enhancement and long term management activities within the boundaries of the Spokane Indian Reservation. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat adversely affected by the construction of Grand Coulee Dam and its reservoir.

  1. Cueing Metacognition to Improve Researching and Essay Writing in a Final Year High School Biology Class

    Science.gov (United States)

    Conner, L. N.

    2007-03-01

    This paper reports on degrees of awareness and use of specific metacognitive strategies by 16 students in a final-year high school biology class in New Zealand. The aims of the intervention were to broaden students' thinking about bioethical issues associated with cancer and to enhance students' use of metacognition. Cues and prompts were used in this unit of work to help students use metacognitive strategies since students did not generally use metacognitive strategies spontaneously. Scaffolding was mediated through the teacher modelling, questioning, cueing or prompting students to evaluate their learning. The research reported here illustrates how teachers can cue students to be more self-directed in their learning. Three case studies illustrate how learning strategies were used differentially. Most students were aware of strategies that could help them to learn more effectively. It was found that those students who were not only aware of but also used strategies to plan, monitor and evaluate their work, produced essays of higher quality.

  2. Linking Biological Responses of Terrestrial N Eutrophication to the Final Ecosystem Goods and Services Classification System

    Science.gov (United States)

    Bell, M. D.; Clark, C.; Blett, T.

    2015-12-01

    The response of a biological indicator to N deposition can indicate that an ecosystem has surpassed a critical load and is at risk of significant change. The importance of this exceedance is often difficult to digest by policy makers and public audiences if the change is not linked to a familiar ecosystem endpoint. A workshop was held to bring together scientists, resource managers, and policy makers with expertise in ecosystem functioning, critical loads, and economics in an effort to identify the ecosystem services impacted by air pollution. This was completed within the framework of the Final Ecosystem Goods and Services (FEGS) Classification System to produce a product that identified distinct interactions between society and the effects of nitrogen pollution. From each change in a biological indicator, we created multiple ecological production functions to identify the cascading effects of the change to a measureable ecosystem service that a user interacts with either by enjoying, consuming, or appreciating the good or service, or using it as an input in the human economy. This FEGS metric was then linked to a beneficiary group that interacts with the service. Chains detailing the links from the biological indicator to the beneficiary group were created for aquatic and terrestrial acidification and eutrophication at the workshop, and here we present a subset of the workshop results by highlighting for 9 different ecosystems affected by terrestrial eutrophication. A total of 213 chains that linked to 37 unique FEGS metrics and impacted 15 beneficiary groups were identified based on nitrogen deposition mediated changes to biological indicators. The chains within each ecosystem were combined in flow charts to show the complex, overlapping relationships among biological indicators, ecosystem services, and beneficiary groups. Strength of relationship values were calculated for each chain based on support for the link in the scientific literature. We produced the

  3. Synthetic Biology in the FDA Realm: Toward Productive Oversight Assessment.

    Science.gov (United States)

    Fatehi, Leili; Hall, Ralph F

    2015-01-01

    Synthetic biology (SB) is expected to create tremendous opportunities in a wide range of areas, including in foods, therapeutics, and diagnostics subject to regulatory oversight by the United States Food and Drug Administration. At the same time, there is substantial basis for concern about the uncertainties of accurately assessing the human health and environmental risks of such SB products. As such, SB is the latest in a string of emerging technologies that is the subject of calls for new approaches to regulation and oversight that involve "thinking ahead" to anticipate governance challenges upstream of technological development and adopting oversight mechanisms that are both adaptive to new information about risks and reflexive to performance data and feedback on policy outcomes over time. These new approaches constitute a marked departure from the status quo, and their development and implementation will require considerable time, resources, and reallocation of responsibilities. Furthermore, in order to develop an appropriate oversight response, adaptive or otherwise, there is first a need to identify the specific types and natures of applications, uncertainties, and regulatory issues that are likely to pose oversight challenges. This article presents our vision for a Productive Oversight Assessment (POA) approach in which the abilities and deficits of an oversight system are evaluated with the aim of enabling productive decisions (i.e., timely, feasible, effective for achieving desired policy outcomes) about oversight while also building capacity to facilitate broader governance efforts. The value ofPOA is two-fold. First, it will advance the development of a generalizable approach for making productive planning and decision-making about the oversight of any given new technology that presents challenges and uncertainties for any given oversight system whose policy goals are implicated by that technology. Second, this effort can enhance the very processes

  4. Snakeheads (Pisces, Channidae): A biological synopsis and risk assessment

    Science.gov (United States)

    Courtenay, Walter R.; Williams, James D.

    2004-01-01

    Snakeheads (family Channidae) are airbreathing freshwater fishes containing two genera, Channa with 26 species native to Asia, Malaysia, and Indonesia; and Parachanna with 3 species native to tropical Africa. Some snakeheads are small, reaching about 17 centimeters, but most are much larger, the largest reported to be 1.8 meters in length. All are considered thrust predators with most being piscivorous as adults. A few of the smaller snakeheads and colorful juveniles of some larger ones have been available to hobbyists through the aquarium fish trade. Several species are highly valued as food fishes within parts of their native ranges, especially in Asia where they are an important part of capture fisheries and aquaculture. Because of these uses by humans, introductions far beyond native ranges have occurred. One Asian snakehead has been established in Oahu, Hawaii, since before 1900. Another species was discovered established in southeastern Florida in 2000, and a third in a pond in Maryland in 2002. Others have been captured from natural waters of the United States without evidence of reproduction and likely represent released aquarium fishes. That snakeheads at or near sexual maturity were being sold alive in ethnic food markets raised fears that they could be introduced into novel waters. These concerns led to this study on the biology of snakeheads. A risk assessment is included that examines environmental and related aspects of snakehead introductions.

  5. Assessment of the Fusion Energy Sciences Program. Final Report

    International Nuclear Information System (INIS)

    An assessment of the Office of Fusion Energy Sciences (OFES) program with guidance for future program strategy. The overall objective of this study is to prepare an independent assessment of the scientific quality of the Office of Fusion Energy Sciences program at the Department of Energy. The Fusion Science Assessment Committee (FuSAC) has been appointed to conduct this study

  6. Life Cycle Assessment of mechanical biological pre-treatment of Municipal Solid Waste: a case study.

    Science.gov (United States)

    Beylot, Antoine; Vaxelaire, Stéphane; Zdanevitch, Isabelle; Auvinet, Nicolas; Villeneuve, Jacques

    2015-05-01

    The environmental performance of mechanical biological pre-treatment (MBT) of Municipal Solid Waste is quantified using Life Cycle Assessment (LCA), considering one of the 57 French plants currently in operation as a case study. The inventory is mostly based on plant-specific data, extrapolated from on-site measurements regarding mechanical and biological operations (including anaerobic digestion and composting of digestate). The combined treatment of 46,929 tonnes of residual Municipal Solid Waste and 12,158 tonnes of source-sorted biowaste (as treated in 2010 at the plant) generates 24,550 tonnes CO2-eq as an impact on climate change, 69,943kg SO2-eq on terrestrial acidification and 19,929kg NMVOC-eq on photochemical oxidant formation, in a life-cycle perspective. On the contrary MBT induces environmental benefits in terms of fossil resource depletion, human toxicity (carcinogenic) and ecotoxicity. The results firstly highlight the relatively large contribution of some pollutants, such as CH4, emitted at the plant and yet sometimes neglected in the LCA of waste MBT. Moreover this study identifies 4 plant-specific operation conditions which drive the environmental impact potentials induced by MBT: the conditions of degradation of the fermentable fraction, the collection of gaseous flows emitted from biological operations, the abatement of collected pollutants and NOx emissions from biogas combustion. Finally the results underline the relatively large influence of the operations downstream the plant (in particular residuals incineration) on the environmental performance of waste MBT.

  7. REVIEW OF SELECTED BIOLOGICAL METHODS OF ASSESSING THE QUALITY OF NATURAL ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Monika Beata Jakubus

    2015-04-01

    Full Text Available The xenobiotics introduced into the environment are the effect of human activities. It is especially soil contamination that leads to degradation of soils, which may finally be referred to the biological imbalance of the ecosystem. Normally chemical methods are used for the assessment of soil’s quality. Unfortunately, they are not always quick and inexpensive. Therefore, the practice and the science at environmental monitoring more frequently employ biological methods. Most of them meet the above mentioned conditions and become a supplement of routine laboratory practices. This publication shows an overview of selected common biological methods used to estimate the quality of the environment. The first part of the paper presents biomonitoring as a first step of environmental control which relies on the observation of indicator organisms. The next section was dedicated to the bioassays, indicating the greater or lesser practical applications confirmed by literature on the subject. Particular attention has been focused on phytotests and the tests based on the invertebrates.

  8. Life Cycle Assessment of mechanical biological pre-treatment of Municipal Solid Waste: a case study.

    Science.gov (United States)

    Beylot, Antoine; Vaxelaire, Stéphane; Zdanevitch, Isabelle; Auvinet, Nicolas; Villeneuve, Jacques

    2015-05-01

    The environmental performance of mechanical biological pre-treatment (MBT) of Municipal Solid Waste is quantified using Life Cycle Assessment (LCA), considering one of the 57 French plants currently in operation as a case study. The inventory is mostly based on plant-specific data, extrapolated from on-site measurements regarding mechanical and biological operations (including anaerobic digestion and composting of digestate). The combined treatment of 46,929 tonnes of residual Municipal Solid Waste and 12,158 tonnes of source-sorted biowaste (as treated in 2010 at the plant) generates 24,550 tonnes CO2-eq as an impact on climate change, 69,943kg SO2-eq on terrestrial acidification and 19,929kg NMVOC-eq on photochemical oxidant formation, in a life-cycle perspective. On the contrary MBT induces environmental benefits in terms of fossil resource depletion, human toxicity (carcinogenic) and ecotoxicity. The results firstly highlight the relatively large contribution of some pollutants, such as CH4, emitted at the plant and yet sometimes neglected in the LCA of waste MBT. Moreover this study identifies 4 plant-specific operation conditions which drive the environmental impact potentials induced by MBT: the conditions of degradation of the fermentable fraction, the collection of gaseous flows emitted from biological operations, the abatement of collected pollutants and NOx emissions from biogas combustion. Finally the results underline the relatively large influence of the operations downstream the plant (in particular residuals incineration) on the environmental performance of waste MBT. PMID:25708404

  9. Mastoidectomy performance assessment of virtual simulation training using final-product analysis

    DEFF Research Database (Denmark)

    Andersen, Steven A W; Cayé-Thomasen, Per; Sørensen, Mads S

    2015-01-01

    OBJECTIVES/HYPOTHESIS: The future development of integrated automatic assessment in temporal bone virtual surgical simulators calls for validation against currently established assessment tools. This study aimed to explore the relationship between mastoidectomy final-product performance assessmen...

  10. Methods for isolation and viability assessment of biological organisms

    Science.gov (United States)

    Letant, Sonia Edith; Baker, Sarah Elyse; Bond, Tiziana; Chang, Allan Shih-Ping

    2015-02-03

    Isolation of biological or chemical organisms can be accomplished using a surface enhanced Raman scattering (SERS) system. The SERS system can be a single or a stacked plurality of photonic crystal membranes with noble-metal lined through pores for flowing analyte potentially containing the biological or chemical organisms. The through pores can be adapted to trap individual biological or chemical organisms and emit SERS spectra, which can then be detected by a detector and further analyzed for viability of the biological or chemical organism.

  11. Biological dose assessment of 15 victims in Haerbin radiation accident

    International Nuclear Information System (INIS)

    unstable aberrations were analyzed and biological dose was assessed according to the dose-effect curves built by our lab member. For micronucleus analysis, blood were added cytochalasin-B after culturing 40 hours. The doses were assessed according to the dose-effect curves built by our lab member. According to a human lymphocyte chromosome aberration and micronucleus analysis, the estimated maximum irradiation dose of 3 exposed patients is lower than 2 Gy, equal to the dose of once uneven total-body irradiation. In vitro dose-response calibration curves for (60)Co gamma rays have been established for unstable chromosome aberrations in human peripheral blood lymphocytes. The observed dose-response data were fitted to a linear quadratic model. The calibration curve parameters were used to estimate the equivalent whole-body dose and dose to the irradiated region in partial body irradiation of cancer patients. The derived partial body doses and fractions of lymphocytes irradiated were in agreement with those estimated from the radiotherapy regimes. (author)

  12. Inventors Center of Michigan Technical Assessment Program. Final progress report

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    The Technical Assessment Program at the Inventors Center of Michigan is designed to provide independent inventors with a reliable assessment of the technical merits of their proposed inventions. Using faculty from within Ferris State University`s College of Technology an assessment process examines the inventor`s assumptions, documentation, and prototypes, as well as, reviewing patent search results and technical literature to provide the inventor with a written report on the technical aspects of the proposed invention. The forms for applying for a technical assessment of an invention are included.

  13. 75 FR 7029 - Notice of Availability of the Final Environmental Assessment for Solar Roof Project

    Science.gov (United States)

    2010-02-16

    ... Geological Survey Notice of Availability of the Final Environmental Assessment for Solar Roof Project AGENCY..., the US Geological Survey (USGS) has prepared a Final Environmental Assessment for the Solar Roof... USGS National Wildlife Health Center, 6006 Schroeder Road, Madison, Wisconsin 53711-6226....

  14. Multiple Intelligences: Curriculum and Assessment Project. Final Report

    Science.gov (United States)

    Hyland, Aine, Ed.

    2011-01-01

    The "Multiple Intelligences, Curriculum and Assessment Project" at University College Cork was a collaborative project carried out between 1995 and 1999. The key research question focused on whether Howard Gardner's theory of Multiple Intelligences could be applied to, and enhance, aspects of curriculum and assessment at primary and second level…

  15. 75 FR 64984 - Availability of an Environmental Assessment for a Biological Control Agent for Hawkweeds

    Science.gov (United States)

    2010-10-21

    ... Assessment for a Biological Control Agent for Hawkweeds AGENCY: Animal and Plant Health Inspection Service... the control of hawkweeds (Hieracium spp.). The environmental assessment considers the effects of, and... States as a biological control agent to reduce the severity of infestations of hawkweeds. We are...

  16. Reno, Nevada Imazapic Ecological Risk Assessment: Final Report

    OpenAIRE

    ENSR International; Bureau of Land Management

    2005-01-01

    The Bureau of Land Management (BLM), United States Department of the Interior (USDI), is proposing a program to treat vegetation on up to six million acres of public lands annually in 17 western states in the continental United States (U.S.) and Alaska. The primary objectives of the proposed program include fuels management, weed control, and fish and wildlife habitat restoration. Vegetation would be managed using five primary vegetation treatment methods: mechanical, manual, biological, chem...

  17. Insects as test systems for assessing the potential role of microgravity in biological development and evolution

    Science.gov (United States)

    Vernós, I.; Carratalá, M.; González-Jurado, J.; Valverde, J. R.; Calleja, M.; Domingo, A.; Vinós, J.; Cervera, M.; Marco, R.

    Gravity and radiation are undoubtedly the two major environmental factors altered in space. Gravity is a weak force, which creates a permanent potential field acting on the mass of biological systems and their cellular components, strongly reduced in space flights. Developmental systems, particularly at very early stages, provide the larger cellular compartments known, where the effects of alterations in the size of the gravity vector on living organisms can be more effectively tested. The insects, one of the more highly evolved classes of animals in which early development occurs in a syncytial embryo, are systems particularly well suited to test these effects and the specific developmental mechanisms affected. Furthermore, they share some basic features such as small size, short life cycles, relatively high radio-resistance, etc. and show a diversity of developmental strategies and tempos advantageous in experiments of this type in space. Drosophila melanogaster, the current biological paradigm to study development, with so much genetic and evolutionary background available, is clearly the reference organism for these studies. The current evidence on the effects of the physical parameters altered in space flights on insect development indicate a surprising correlation between effects seen on the fast developing and relatively small Drosophila embryo and the more slowly developing and large Carausius morosus system. In relation to the issue of the importance of developmental and environmental constraints in biological evolution, still the missing link in current evolutionary thinking, insects and space facilities for long-term experiments could provide useful experimental settings where to critically assess how development and evolution may be interconnected. Finally, it has to be pointed out that since there are experimental data indicating a possible synergism between microgravity and space radiation, possible effects of space radiation should be taken into

  18. Social impact assessment: A review and proposed approach: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Bradbury, J A

    1986-12-01

    The objective of the report is to identify the essential components of a comprehensive plan to assess the potential social impacts of the proposed construction and operation of a high level radioactive waste repository by the Nevada Nuclear Waste Storage Investigations (NNWSI) Project. The tasks taken to achieve this objective are: examination of the literature on Social Impact Assessment (SIA); identification of different conceptual frameworks that have been proposed or used in SIA; examination of specific aspects of the frameworks; assessment of strengths and weaknesses of the frameworks; synthesis of common elements in these frameworks; and examination and evaluation of methods of data collection and analysis. 150 refs., 6 figs., 7 tabs.

  19. Social impact assessment: A review and proposed approach: Final report

    International Nuclear Information System (INIS)

    The objective of the report is to identify the essential components of a comprehensive plan to assess the potential social impacts of the proposed construction and operation of a high level radioactive waste repository by the Nevada Nuclear Waste Storage Investigations (NNWSI) Project. The tasks taken to achieve this objective are: examination of the literature on Social Impact Assessment (SIA); identification of different conceptual frameworks that have been proposed or used in SIA; examination of specific aspects of the frameworks; assessment of strengths and weaknesses of the frameworks; synthesis of common elements in these frameworks; and examination and evaluation of methods of data collection and analysis. 150 refs., 6 figs., 7 tabs

  20. Implementing the Science Assessment Standards: Developing and validating a set of laboratory assessment tasks in high school biology

    Science.gov (United States)

    Saha, Gouranga Chandra

    Very often a number of factors, especially time, space and money, deter many science educators from using inquiry-based, hands-on, laboratory practical tasks as alternative assessment instruments in science. A shortage of valid inquiry-based laboratory tasks for high school biology has been cited. Driven by this need, this study addressed the following three research questions: (1) How can laboratory-based performance tasks be designed and developed that are doable by students for whom they are designed/written? (2) Do student responses to the laboratory-based performance tasks validly represent at least some of the intended process skills that new biology learning goals want students to acquire? (3) Are the laboratory-based performance tasks psychometrically consistent as individual tasks and as a set? To answer these questions, three tasks were used from the six biology tasks initially designed and developed by an iterative process of trial testing. Analyses of data from 224 students showed that performance-based laboratory tasks that are doable by all students require careful and iterative process of development. Although the students demonstrated more skill in performing than planning and reasoning, their performances at the item level were very poor for some items. Possible reasons for the poor performances have been discussed and suggestions on how to remediate the deficiencies have been made. Empirical evidences for validity and reliability of the instrument have been presented both from the classical and the modern validity criteria point of view. Limitations of the study have been identified. Finally implications of the study and directions for further research have been discussed.

  1. Final Addendum to the Necedah National Wildlife Refuge Environmental Assessment

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this Addendum is to clarify actions that will be taken under the selected alternative for the Fire Management Plan Environmental Assessment that was...

  2. Nevada low-temperaure geothermal resource assessment: 1994. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Garside, L.J.

    1994-12-31

    Data compilation for the low-temperature program is being done by State Teams in two western states. Final products of the study include: a geothermal database, in hardcopy and as digital data (diskette) listing information on all known low- and moderate- temperature springs and wells in Nevada; a 1:1,000,000-scale map displaying these geothermal localities, and a bibliography of references on Nevada geothermal resources.

  3. Biological assessments for the low energy demonstration accelerator, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Cross, S.

    1997-03-01

    This report discusses the biological impact to the area around the Los Alamos National Laboratory of the Low Energy Demonstration Accelerator. In particular the impact to the soils, water quality, vegetation, and wildlife are discussed.

  4. General support for integrated assessment research. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Dowlatabadi, Hadi

    2001-03-01

    The climate change problem spans an extraordinarily large number of disciplines from earth sciences to social and political sciences. The interaction of processes described by these different fields is why climate change is such a complex issue. Keeping track of these interactions and bringing coherence to the assumptions underlying each disciplinary insight on the climate problem is a massive undertaking. Integrated assessment is an interdisciplinary approach designed to provide systematic evaluations of technically complex problems such as the analysis of environmental change challenges facing humanity. Ph.D. theses stemming from this application are summarized. Then some aspects of Integrated Climate Assessment Models are described.

  5. Darwin y la imposibilidad de causas finales en la biología

    Directory of Open Access Journals (Sweden)

    Corral Cuartas Álvaro

    2009-12-01

    Full Text Available La teoría de la selección natural propuesta por Charles Darwin en su obra El Origen de las Especies no sólo colocó las bases para una explicación coherente de los hechos fundamentales de la biología (el origen común de los seres vivos, la diversidad de individuos y especies y la transmisión de características hereditarias, sino que además introduce maneras nuevas de hacer filosofía. La teoría de la selección natural hace superflua cualquier posibilidad de apelar a explicaciones de tipo finalista en la ciencia. Desde Aristóteles se conocen cuatro tipos de causa: la material, la formal, la eficiente y la final. Aunque la causa eficiente es el paradigma de explicación por excelencia de las ciencias empíricas, la causa final sigue desempeñando un papel explicativo, por cuanto parece estar arraigada en nuestra estructura humana de pensamiento y la tendencia a presentar explicaciones finalistas sigue siendo recalcitrante. Quizá por estar los seres humanos tan familiarizados con la complejidad inherente a los procesos de diseño en las artes y en la técnica, suponemos por vía de analogía que la naturaleza en su complejidad exige la presencia y acción de un diseñador inteligente. Kant en la Crítica de la facultad de juzgar hace una defensa del carácter “irrenunciable” de este modelo explicativo. Para controvertir esta opinión, me apoyaré, en recientes investigaciones de Richard Dawkins y de otros biólogos contemporáneos para mostrar con la evolución de ojos en la naturaleza que el surgimiento de órganos de alta complejidad puede ser explicado sin

  6. Primary Science Assessment Item Setters' Misconceptions Concerning Biological Science Concepts

    Science.gov (United States)

    Boo, Hong Kwen

    2007-01-01

    Assessment is an integral and vital part of teaching and learning, providing feedback on progress through the assessment period to both learners and teachers. However, if test items are flawed because of misconceptions held by the question setter, then such test items are invalid as assessment tools. Moreover, such flawed items are also likely to…

  7. Final Technical Report - Use of Systems Biology Approaches to Develop Advanced Biofuel-Synthesizing Cyanobacterial Strains

    Energy Technology Data Exchange (ETDEWEB)

    Pakrasi, Himadri [Washington Univ., St. Louis, MO (United States)

    2016-09-01

    The overall objective of this project was to use a systems biology approach to evaluate the potentials of a number of cyanobacterial strains for photobiological production of advanced biofuels and/or their chemical precursors. Cyanobacteria are oxygen evolving photosynthetic prokaryotes. Among them, certain unicellular species such as Cyanothece can also fix N2, a process that is exquisitely sensitive to oxygen. To accommodate such incompatible processes in a single cell, Cyanothece produces oxygen during the day, and creates an O2-limited intracellular environment during the night to perform O2-sensitive processes such as N2-fixation. Thus, Cyanothece cells are natural bioreactors for the storage of captured solar energy with subsequent utilization at a different time during a diurnal cycle. Our studies include the identification of a novel, fast-growing, mixotrophic, transformable cyanobacterium. This strain has been sequenced and will be made available to the community. In addition, we have developed genome-scale models for a family of cyanobacteria to assess their metabolic repertoire. Furthermore, we developed a method for rapid construction of metabolic models using multiple annotation sources and a metabolic model of a related organism. This method will allow rapid annotation and screening of potential phenotypes based on the newly available genome sequences of many organisms.

  8. Summative Self-Assessment in Higher Education: Implications of Its Counting towards the Final Mark

    Science.gov (United States)

    Tejeiro, Ricardo A.; Gomez-Vallecillo, Jorge L.; Romero, Antonio F.; Pelegrina, Manuel; Wallace, Agustin; Emberley, Enrique

    2012-01-01

    Introduction: Our study aims at assessing the validity of summative criteria-referenced self-assessment in higher education, and in particular, if that validity varies when the professor counts self-assessment toward the final mark. Method: One hundred and twenty-two first year students from two groups in Teacher Education at the Universidad de…

  9. Anti-tick biological control agents: assessment and future perspectives

    Science.gov (United States)

    Samish, M., H.; Ginsberg, H.S.; Glazer, I.

    2008-01-01

    Widespread and increasing resistance to most available acaracides threatens both global livestock industries and public health. This necessitates better understanding of ticks and the diseases they transmit in the development of new control strategies. Ticks: Biology, Disease and Control is written by an international collection of experts and covers in-depth information on aspects of the biology of the ticks themselves, various veterinary and medical tick-borne pathogens, and aspects of traditional and potential new control methods. A valuable resource for graduate students, academic researchers and professionals, the book covers the whole gamut of ticks and tick-borne diseases from microsatellites to satellite imagery and from exploiting tick saliva for therapeutic drugs to developing drugs to control tick populations. It encompasses the variety of interconnected fields impinging on the economically important and biologically fascinating phenomenon of ticks, the diseases they transmit and methods of their control.

  10. Optimization of biological phosphorus and ammonia removal in a combined fixed and suspended growth wastewater treatment system: Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This project was conducted to optimize design and operational criteria for enhanced biological phosphorus removal and nitrification of ammonia in the fixed growth reactor-suspended growth reactor (FGR-SGR) process. The research completed the investigation of optimum hydraulic retention times for biological phosphorus removal in both the unaerated and aerated phases of the suspended growth components of the FGR-SGR system, including an assessment of the possibility of reducing suspended growth aeration requirements by using oxidized forms of nitrogen rather than dissolved oxygen for biological phosphorus uptake; investigated the effects on biological phosphorus removal and nitrification of varying the internal recycle flow rates; and investigated the optimum solids retention time, or the optimum operating mixed liquor suspended solids concentration, in the suspended growth component of the system for biological phosphorus removal and nitrification-denitrification.

  11. Final Technical Report for University of Michigan Industrial Assessment Center

    Energy Technology Data Exchange (ETDEWEB)

    Atreya, Arvind

    2007-04-17

    The UM Industrial Assessment Center assisted 119 primary metals, automotive parts, metal casting, chemicals, forest products, agricultural, and glass manufacturers in Michigan, Ohio and Indiana to become more productive and profitable by identifying and recommending specific measures to improve energy efficiency, reduce waste and increase productivity. This directly benefits the environment by saving a total of 309,194 MMBtu of energy resulting in reduction of 0.004 metric tons of carbon emissions. The $4,618,740 implemented cost savings generated also saves jobs that are evaporating from the manufacturing industries in the US. Most importantly, the UM Industrial Assessment Center provided extremely valuable energy education to forty one UM graduate and undergraduate students. The practical experience complements their classroom education. This also has a large multiplier effect because the students take the knowledge and training with them.

  12. Industrial assessment of nonbackfittable PWR design modifications. Final report

    International Nuclear Information System (INIS)

    As part of the US Department of Energy's Advanced Reactor Design Study, various nonbackfittable PWR design modifications were evaluated to determine their potential for improved uranium utilization and commercial viability. Combustion Engineering, Inc. contributed to this effort through participation in the Battelle Pacific Northwest Laboratory industrial assessment of such design modifications. Seven modifications, including the use of higher primary system temperatures and pressures, rapid-frequent refueling, end-of-cycle stretchout, core periphery modifications, radial blankets, low power density cores, and small PWR assemblies, were evaluated with respect to uranium utilization, economics, technical and operational complexity, and several other subjective considerations. Rapid-frequent refueling was judged to have the highest potential although it would probably not be economical for the majority of reactors with the design assumptions used in this assessment

  13. Power plant system assessment. Final report. SP-100 Program

    International Nuclear Information System (INIS)

    The purpose of this assessment was to provide system-level insights into 100-kWe-class space reactor electric systems. Using these insights, Rockwell was to select and perform conceptual design studies on a ''most attractive'' system that met the preliminary design goals and requirements of the SP-100 Program. About 4 of the 6 months were used in the selection process. The remaining 2 months were used for the system conceptual design studies. Rockwell completed these studies at the end of FY 1983. This report summarizes the results of the power plant system assessment and describes our choice for the most attractive system - the Rockwell SR-100G System (Space Reactor, 100 kWe, Growth) - a lithium-cooled UN-fueled fast reactor/Brayton turboelectric converter system

  14. Influence choreographic readiness to gymnasts final assessment of performance skills

    Directory of Open Access Journals (Sweden)

    Omelichyk-Ziurkalova O.A.

    2014-06-01

    Full Text Available Purpose : to provide a quantitative assessment and expert choreographic preparedness gymnasts. Material : the study involved eight gymnasts competition finalists in the floor exercise - female members of the Ukrainian national team in gymnastics. Results : the quantitative indicators of acrobatic and dance elements to determine the baseline assessment. Defined methods complications composition on the floor exercise by reducing the number of acrobatic lines and diagonals and increase the number of gymnastic elements. The theoretical performance of the composite sequence is improved structure and increases the difficulty of the exercise. Conclusions : in the process of composition complications need to pay more attention to the technique of performing gymnastic elements. In improving exercise choreography element replace (in some cases acrobatic element. Based on the results is planned future direction of research in order to improve the training process in gymnastics.

  15. Lake Mead Complex Final Gather Plan: Environmental Assessment

    OpenAIRE

    U.S. Department of the Interior, Bureau of Land Management, Grand Junction Field Office, Grand Junction, Colorado

    2007-01-01

    This Environmental Assessment (EA) has been prepared by the Bureau of Land Management (BLM) Las Vegas Field Office (LVFO) to analyze the environmental effects of a gather to remove approximately 195 resident wild burros from National Park Service-administered lands adjacent to the El Dorado Mountains, Gold Butte and Muddy Mountains Herd Management Areas (HMAs) within the Lake Mead Complex (LMC) in March 2007. The LMC is located in southern Nevada in Clark County. The BLM Las Vegas Field Offic...

  16. CAISI Operational Assessment (OA) data collection results. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-31

    One of the lessons learned from Operation Desert Shield/Storm was the inability of deployed Combat Service Support (CSS) computers to exchange data effectively in a battlefield environment. The work-around solution to this previously identified problem has been to physically carry floppy disks between computers. A General Officer Steering Committee, directed by the Vice Chief of Staff of the Army, determined that immediate corrective action was necessary to ensure viability of the CSS Battlefield Mission Area. The study recommended that a three-phased system development plan address short-, mid- and long-term CSS automation communication interface requirements. In response to this study, Program Executive Office (PEO) Standard Army Management Information System (STAMIS) authorized the development of the CSS Automated Information System Interface (CAISI). Phase I (Near-Term) equipped the {open_quotes}first to fight{close_quotes} Contingency Corps units. Phase II (Mid-Term) is being fielded to the remainder of Force Package One units in the active force. Phase III (Long-Term) will equip the remaining units. CAISI is now in the early stages of Phase II fielding. Prior to full Phase II fielding, CAISI must be approved for production by a Milestone III decision authority. Part of the data that will be used in the Milestone III decision is a demonstration of the CAISI`s operational suitability, as assessed by the US Army Operational Test and Evaluation Command (OPTEC). This assessment will be performed through an Operational Assessment (OA) using data provided from previous technical testing, such as the CAISI Customer User Test (CUT), and a field training exercise conducted by units of the XVIII Airborne Corps. The field training exercise data collection took place during two events.

  17. Final Technical Report: Renewable Energy Feasibility Study and Resources Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rivero, Mariah [BEC Environmental, Inc., Las Vegas, NV (United States)

    2016-02-28

    In March 2011, the U.S. Department of Energy (DOE) awarded White Pine County, Nevada, a grant to assess the feasibility of renewable resource-related economic development activities in the area. The grant project included a public outreach and training component and was to include a demonstration project; however, the demonstration project was not completed due to lack of identification of an entity willing to locate a project in White Pine County. White Pine County completed the assessment of renewable resources and a feasibility study on the potential for a renewable energy-focused economic sector within the County. The feasibility study concluded "all resources studied were present and in sufficient quantity and quality to warrant consideration for development" and there were varying degrees of potential economic impact based on the resource type and project size. The feasibility study and its components were to be used as tools to attract potential developers and other business ventures to the local market. White Pine County also marketed the County’s resources to the renewable energy business community in an effort to develop contracts for demonstration projects. The County also worked to develop partnerships with local educational institutions, including the White Pine County School District, conducted outreach and training for the local community.

  18. Comparative assessment of marine biomass materials. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Show, I.T. Jr.; Piper, L.E.; Lupton, S.E.; Stegen, G.R.

    1979-09-01

    The objectives of this study were to assess potential marine biomass sources and their preprocessing requirements. For the assessment of marine biomass sources, a priority list of marine plants was developed based on maximum potential organic yields, maximum potential calorific yields, and chemical composition. Yields were maximized and undesirable chemical properties minimized. The priority list was used to estimate maximum potential yields from US coastal water (from shore to the 200-mile limit of the Fisheries Conservation Zone). Preprocessing schemes were compared based on a comparative evaluation of energy consumption for each preprocessing step. The priority list of potential biomass sources produced 13 potential genera; five showed calorific yields far in excess of the other eight. These five (Laminaria, Chondrus, Fucus, Gracilaria, and Macrocystis) had calorific yields in excess of 50 x 10/sup 3/ kcal/m/sup 2/ - yr. No genus was found to be universally applicable to all US territorial waters. It was estimated that maximum potential national yield without mechanical nutrient upwelling could be as high as 30 x 10/sup 5/ Btu/yr (30 quad). Results of the preprocessing study indicated that harvesting and size reduction operations may consume a large proportion of the energy available from the harvested biomass. It was found that biochemical conversion preprocessing incurs the least energy loss. It was also found that thermochemical conversion is probably not appropriate for marine biomass due to preprocessing energy losses.

  19. Final Environmental assessment for the Uranium Lease Management Program

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) has prepared a programmatic environmental assessment (EA) of the proposed action to continue leasing withdrawn lands and DOE-owned patented claims for the exploration and production of uranium and vanadium ores. The Domestic Uranium Program regulation, codified at Title 10, Part 760.1, of the US Code of Federal Regulations (CFR), gives DOE the flexibility to continue leasing these lands under the Uranium Lease Management Program (ULMP) if the agency determines that it is in its best interest to do so. A key element in determining what is in DOE's ''best interest'' is the assessment of the environmental impacts that may be attributable to lease tract operations and associated activities. On the basis of the information and analyses presented in the EA for the ULMP, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined in the National Environmental Policy Act (NEPA) of 1969 (42 United States Code 4321 et seq.), as amended.Therefore, preparation of an environmental impact statement is not required for the ULMP,and DOE is issuing this Finding, of No Significant Impact (FONSI)

  20. Final Environmental assessment for the Uranium Lease Management Program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The US Department of Energy (DOE) has prepared a programmatic environmental assessment (EA) of the proposed action to continue leasing withdrawn lands and DOE-owned patented claims for the exploration and production of uranium and vanadium ores. The Domestic Uranium Program regulation, codified at Title 10, Part 760.1, of the US Code of Federal Regulations (CFR), gives DOE the flexibility to continue leasing these lands under the Uranium Lease Management Program (ULMP) if the agency determines that it is in its best interest to do so. A key element in determining what is in DOE`s ``best interest`` is the assessment of the environmental impacts that may be attributable to lease tract operations and associated activities. On the basis of the information and analyses presented in the EA for the ULMP, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined in the National Environmental Policy Act (NEPA) of 1969 (42 United States Code 4321 et seq.), as amended.Therefore, preparation of an environmental impact statement is not required for the ULMP,and DOE is issuing this Finding, of No Significant Impact (FONSI).

  1. Final Report Low-temperature Resource Assessment Program

    Energy Technology Data Exchange (ETDEWEB)

    Lienau, P.J. [Geo-Heat Center, Oregon Institute of Technology, Klamath Falls, OR (US); Ross, H. [Earth Sciences and Resources Institute, University of Utah

    1996-02-01

    The U.S. Department of Energy - Geothermal Division (DOE/GD) recently sponsored the Low-Temperature Resource Assessment project to update the inventory of the nation's low- and moderate-temperature geothermal resources and to encourage development of these resources. A database of 8,977 thermal wells and springs that are in the temperature range of 20 degrees Celsius to 150 degrees Celsius has been compiled for ten western states, an impressive increase of 82% compared to the previous assessments. The database includes location, descriptive data, physical parameters, water chemistry and references for sources of data. Computer-generated maps are also available for each state. State Teams have identified 48 high-priority areas for near-term comprehensive resource studies and development. Resources with temperatures greater than 50 degrees Celsius located within 8 km of a population center were identified for 271 collocated cities. Geothermal energy costevaluation software has been developed to quickly identify the cost of geothermally supplied heat to these areas in a fashion similar to that used for conventionally fueled heat sources.

  2. Low-temperature resource assessment program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lienau, P.J. [Oregon Inst. of Tech., Klamath Falls, OR (United States). Geo-Heat Center; Ross, H. [Utah Univ., Salt Lake City, UT (United States). Earth Sciences and Resources Inst.

    1996-02-01

    The US Department of Energy - Geothermal Division (DOE/GD) recently sponsored the Low-Temperature Resource Assessment project to update the inventory of the nation`s low- and moderate-temperature geothermal resources and to encourage development of these resources. A database of 8,977 thermal wells and springs that are in the temperature range of 20{degrees}C to 150{degrees}C has been compiled for ten western states, an impressive increase of 82% compared to the previous assessments. The database includes location, descriptive data, physical parameters, water chemistry and references for sources of data. Computer-generated maps are also available for each state. State Teams have identified 48 high-priority areas for near-term comprehensive resource studies and development. Resources with temperatures greater than 50{degrees}C located within 8 km of a population center were identified for 271 collocated cities. Geothermal energy cost evaluation software has been developed to quickly identify the cost of geothermally supplied heat to these areas in a fashion similar to that used for conventionally fueled heat sources.

  3. Final Environmental Assessment for the Proposed Wallkill River National Wildlife Refuge 1990

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Final Environmental Assessment for the proposed acquisition and establishment of Wallkill River National Wildlife Refuge in Sussex Country, New Jersey. The...

  4. Biology Needs a Modern Assessment System for Professional Productivity

    Science.gov (United States)

    McDade, Lucinda A.; Maddison, David R.; Guralnick, Robert; Piwowar, Heather A.; Jameson, Mary Liz; Helgen, Kristofer M.; Herendeen, Patrick S.; Hill, Andrew; Vis, Morgan L.

    2011-01-01

    Stimulated in large part by the advent of the Internet, research productivity in many academic disciplines has changed dramatically over the last two decades. However, the assessment system that governs professional success has not kept pace, creating a mismatch between modes of scholarly productivity and academic assessment criteria. In this…

  5. 78 FR 62359 - Red River Hydro LLC; Notice of Availability of Final Environmental Assessment

    Science.gov (United States)

    2013-10-21

    ..., 52 FR 47897), the Office of Energy Projects has reviewed Red River Hydro LLC's application for an... Energy Regulatory Commission Red River Hydro LLC; Notice of Availability of Final Environmental... prepared a final environmental assessment (EA). The project would be located on the Red River in...

  6. Policy implications of select student characteristics and their influence on the Florida biology end-of-course assessment

    Science.gov (United States)

    Bertolotti, Janine Cecelia

    In an attempt to improve student achievement in science in Florida, the Florida Department of Education implemented end-of-course (EOC) assessments in biology during the 2011-2012 academic school year. Although this first administration would only account for 30% of the student's overall final course grade in biology, subsequent administrations would be accompanied by increasing stakes for students, teachers, and schools. Therefore, this study sought to address gaps in empirical evidence as well as discuss how educational policy will potentially impact on teacher evaluation and professional development, student retention and graduation rates, and school accountability indicators. This study explored four variables- reading proficiency, ethnicity, socioeconomic status, and gender- to determine their influence and relationship on biology achievement on the Biology I EOC assessment at a Title 1 school. To do so, the results of the Biology I EOC assessment administered during the Spring 2012 school year was obtained from a small, rural Title 1 high school in North Florida. Additional data regarding each student's qualification for free and reduced-price lunch, FCAT Reading developmental scale scores, FCAT Reading level, grade level, gender, and ethnicity were also collected for the causal-comparative exploratory study. Of the 178 students represented, 48% qualified for free and reduced-price lunch, 54% were female, and 55% scored at FCAT Reading level 3 or higher. Additionally, 59% were White and 37% Black. A combination of descriptive statistics and other statistical procedures such as independent samples one-tailed t-test, one-way ANOVAs, ANCOVAs, multipleregression, and a Pearson r correlation was utilized in the analysis, with a significance level set at 0.05. Results indicate that of all four variables, FCAT Reading proficiency was the sole variable, after adjusting for other variables; that had a significant impact on biology achievement. Students with higher

  7. CleanFleet. Final report: Volume 5, employee attitude assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    The experiences of couriers, operations managers, vehicle handlers (refuelers), and mechanics who drove and/or worked with alternative fuel vehicles, and the attitudes and perceptions of people with these experiences, are examined. Five alternative fuels studied in the CleanFleet project are considers& compressed natural gas, propane gas, California Phase 2 reformulated gasoline, M-85, and electricity. The three major areas of interest include comparative analysis of issues such as health, safety and vehicle performance, business issues encompassing several facets of station operations, and personal commentary and opinions about the CleanFleet project and the alterative fuels. Results of the employee attitude assessment are presented as both statistical and qualitative analysis.

  8. BPA/PGE transmission support project: Final environmental assessment

    International Nuclear Information System (INIS)

    This Mitigation Action Plan describes the mitigation measures identified in the BPA/PGE Transmission Support Project Environmental Assessment. These measures commit to actions that will reduce the environmental impacts that could occur by constructing, operating and maintaining the transmission line and related facilities. They have been developed in coordination with environmental specialists, design and construction engineers and maintenance personnel. The measures will be written into the construction specifications for the project, which is expected to be constructed by contract personnel. Unless noted in the plan, the construction inspector or the line foreman would be responsible for carrying out the mitigation; environmental staff would also monitor the area for mitigation effectiveness. The right-of-way would be cleared in 1997 or 1998, and construction would begin in the spring of 1998 and be completed later that fall

  9. Assessment of biological Hydrogen production processes: A review

    Science.gov (United States)

    Najafpour, G. D.; Shahavi, M. H.; Neshat, S. A.

    2016-06-01

    Energy crisis created a special attention on renewable energy sources. Among these sources; hydrogen through biological processes is well-known as the most suitable and renewable energy sources. In terms of process yield, hydrogen production from various sources was evaluated. A summary of microorganisms as potential hydrogen producers discussed along with advantages and disadvantages of several bioprocesses. The pathway of photo-synthetic and dark fermentative organisms was discussed. In fact, the active enzymes involved in performance of biological processes for hydrogen generation were identified and their special functionalities were discussed. The influential factors affecting on hydrogen production were known as enzymes assisting liberation specific enzymes such as nitrogenase, hydrogenase and uptake hydrogenase. These enzymes were quite effective in reduction of proton and form active molecular hydrogen. Several types of photosynthetic systems were evaluated with intension of maximum hydrogen productivities. In addition dark fermentative and light intensities on hydrogen productions were evaluated. The hydrogen productivities of efficient hydrogen producing strains were evaluated.

  10. Actinide partitioning-transmutation program final report. I. Overall assessment

    International Nuclear Information System (INIS)

    This report is concerned with an overall assessment of the feasibility of and incentives for partitioning (recovering) long-lived nuclides from fuel reprocessing and fuel refabrication plant radioactive wastes and transmuting them to shorter-lived or stable nuclides by neutron irradiation. The principal class of nuclides considered is the actinides, although a brief analysis is given of the partitioning and transmutation (P-T) of 99Tc and 129I. The results obtained in this program permit us to make a comparison of the impacts of waste management with and without actinide recovery and transmutation. Three major conclusions concerning technical feasibility can be drawn from the assessment: (1) actinide P-T is feasible, subject to the acceptability of fuels containing recycle actinides; (2) technetium P-T is feasible if satisfactory partitioning processes can be developed and satisfactory fuels identified (no studies have been made in this area); and (3) iodine P-T is marginally feasible at best because of the low transmutation rates, the high volatility, and the corrosiveness of iodine and iodine compounds. It was concluded on the basis of a very conservative repository risk analysis that there are no safety or cost incentives for actinide P-T. In fact, if nonradiological risks are included, the short-term risks of P-T exceed the long-term benefits integrated over a period of 1 million years. Incentives for technetium and iodine P-T exist only if extremely conservative long-term risk analyses are used. Further RD and D in support of P-T is not warranted

  11. Metropolitan Programs in Applied Biological and Agricultural Occupations; A Need and Attitude Study. Final Report.

    Science.gov (United States)

    Thomas, Hollie B.; And Others

    To establish the feasibility of implementing applied biological and agricultural occupations programs in the metropolitan area of Chicago, four populations were surveyed by means of mailed questionnaires or interest inventories to determine: (1) the employment opportunities in the applied biological and agricultural industries, (2) the interests…

  12. Assessment of Constructed Wetland Biological Integrity Using Aquatic Macroinvertebrates

    Directory of Open Access Journals (Sweden)

    C. Galbrand

    2007-01-01

    Full Text Available A surface flow constructed wetland consisting of seven cells was used to treat the leachates from a decommissioned landfill. Wetland monitoring was performed by evaluating the treatment efficiency of the landfill leachate and the wetland biological integrity of the wetland. The water quality samples were analyzed for iron, manganese, phosphorus (orthophosphate, pH, dissolved oxygen (DO, nitrogen (ammonia, nitrate, nitrite and TKN, chemical oxygen demand (COD, total suspended solids (TSS and total dissolved solids (TDS. Aquatic macroinvertebrates were examined using Average Score per Taxon (ASPT via the Biological Monitoring Working Party (BMWP biotic index, the Ephemeroptera, Trichoptera, Sphaeriidae and Odonata (ETSD biotic index, abundance of mayflies and trophic structure. Reductions of 49.66, 66.66, 1.91, 46.37 and 8.33% were obtained for manganese, orthophosphate, TSS, TDS and COD, respectively. The nitrite, dissolved oxygen and iron concentrations were not in accordance with the water quality guidelines for aquatic life. ASPT, ETSD, percent abundance of mayflies and trophic structure represented moderate to moderately-poor water quality in comparison to a high quality reference site. Iron had most adverse effect on the biological system of the wetland.

  13. Synthesis of N11-anchoring biotinylated artemisinin derivatives and their preliminary biological assessment

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Unique endoperoxide moiety of artemisinin and its derivatives has been considered the functionality exhibiting highly potent antimalarial and anticancer activities.To investigate the mechanisms of their biological actions,development of suitable molecular probes including biotinylated derivatives is of extreme significance.The synthesis and preliminary biological assessment of four new biotinylated artemisinin derivatives have been reported in this work.

  14. Development and Assessment of Modules to Integrate Quantitative Skills in Introductory Biology Courses

    OpenAIRE

    Hoffman, Kathleen; Leupen, Sarah; Dowell, Kathy; Kephart, Kerrie; Leips, Jeff

    2016-01-01

    Recent reports have called for integrating quantitative reasoning into biology courses to prepare students for careers in research and medicine. This article describes the development, implementation, and assessment of modules designed to incorporate quantitative reasoning and skill development into introductory biology courses.

  15. A preliminary biological assessment of Long Lake National Wildlife Refuge Complex, North Dakota

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report represents an initial biological assessment of wetland conditions on Long Lake National Wildlife Refuge (NWR), Slade NWR, and Florence Lake NWR that was...

  16. Texas A&M University Industrial Assessment Center Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Heffington, Warren M.; Eggebrecht, James A.

    2007-02-24

    This project benefited the public by assisting manufacturing plants in the United States to save costly energy resources and become more profitable. Energy equivalent to over 75,000 barrels of oil was conserved. The Texas A&M University Industrial Assessment Center (IAC) visited 96 manufacturing plants and spent 101 days in those plants during the contract period from August 9, 2002, through November 30, 2006. Recommended annual energy savings for manufacturers were 37,400,000 kWh (127,600 MMBtu—site basis) of electricity and 309,000 MCF (309,000 MMBtu) of natural gas. Each manufacturer subsequently was surveyed, and based on these surveys reportedly implemented 79% of the electricity savings and 36% of the natural gas savings for an overall energy savings of 48% of recommended. Almost 800 (798) projects were recommended to manufacturers, and they accomplished two-thirds of the projects. Cost savings recommended were $12.3 million and implemented savings were $5.7 million or 47%. During the contract period our average time between site visit and report submittal averaged 46 days; and decreased from 48 days in 2003 to 44 days in 2006. Serving clients well and promptly has been a priority. We visited five ESA overflow clients during FY 06. The Texas A&M University IAC pioneered the presentation of air pollution information in reports, and includes NOx and CO2 reductions due to energy savings in all reports. We also experimented with formal PowerPoint BestPractices presentations called Lunchtime/Showtime in each plant and with delivering electronic versions of the report. During the period of the contract, the director served on the Texas Industries of the Future (IOF) Refining and Chemicals Committee, which oversaw the showcases in 2003 and 2006. The assistant director was the Executive Director of the International Energy Technology Conference held annually. The director and assistant director became qualified specialists in the Process Heating Assessment Scoping

  17. Hellsgate Winter Range: Wildlife Mitigation Project. Final Environmental Assessment

    International Nuclear Information System (INIS)

    BPA proposes to fund the Hellsgate Winter Range: Wildlife Mitigation Project (Project) in a cooperative effort with the Colville Confederated Tribes and the Bureau of Indian Affairs (BIA). The Project is intended to mitigate for wildlife and wildlife habitat adversely affected by the construction of Grand Coulee and Chief Joseph Dams and their reservoirs. The Project would allow the sponsors to secure land and conduct wildlife habitat improvement and long-term management activities within the boundaries of the Colville Indian Reservation. BPA has prepared an Environmental Assessment (EA) (DOE/EA-0940) evaluating the potential environmental effects of the proposed Project (Alternative B) and No Action (Alternative A). Protection and re-establishment of riparian and upland habitat on the Colville Indian Reservation, under Alternative B, would not have a significant adverse environmental impact because: (1) there would be only limited, mostly short-term adverse impacts on soils, water quality, air quality, vegetation, and wildlife (including no effect on endangered species); and (2) there would be no adverse effect on water quantity, cultural resources, or land use. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required and BPA is issuing this FONSI

  18. Willow Creek Wildlife Mitigation Project. Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    Today`s notice announces BPA`s proposal to fund land acquisition or acquisition of a conservation easement and a wildlife management plan to protect and enhance wildlife habitat at the Willow Creek Natural Area in Eugene, Oregon. This action would provide partial mitigation for wildlife and wildlife habitat lost by the development of Federal hydroelectric projects in the Willamette River Basin. The project is consistent with BPA`s obligations under provisions of the Pacific Northwest Electric Power Planning and Conservation Act of 1980 as outlined by the Northwest Power Planning Council`s 1994 Columbia River Basin Fish and Wildlife Program. BPA has prepared an environmental assessment (DOE/EA-1023) evaluating the proposed project. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an environmental impact statement (EIS) is not required and BPA is issuing this FONSI.

  19. Willow Creek Wildlife Mitigation Project. Final environmental assessment

    International Nuclear Information System (INIS)

    Today's notice announces BPA's proposal to fund land acquisition or acquisition of a conservation easement and a wildlife management plan to protect and enhance wildlife habitat at the Willow Creek Natural Area in Eugene, Oregon. This action would provide partial mitigation for wildlife and wildlife habitat lost by the development of Federal hydroelectric projects in the Willamette River Basin. The project is consistent with BPA's obligations under provisions of the Pacific Northwest Electric Power Planning and Conservation Act of 1980 as outlined by the Northwest Power Planning Council's 1994 Columbia River Basin Fish and Wildlife Program. BPA has prepared an environmental assessment (DOE/EA-1023) evaluating the proposed project. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an environmental impact statement (EIS) is not required and BPA is issuing this FONSI

  20. Biological test methods for the ecotoxicological characterization of wastes. Final report; Biologische Testerverfahren zur oekotoxikologischen Charakterisierung von Abfaellen. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Roland [Bundesanstalt fuer Materialforschung, Berlin (Germany); Donnevert, Gerhild [Fachhochschule Giessen-Friedberg (Germany). FB MNI; Roembke, Joerg [ECT Oekotoxikologie GmbH, Floersheim am Main (Germany)

    2007-11-15

    battery the acceptance rate varied between 74.1% (Algae test) and 92.6% (Daphnia test). Methodologically, no problems occurred but further guidance on moisture determination in the terrestrial tests as well as details concerning reference testing and data evaluation for several tests are needed. Independently which test system is considered, SOI always caused the lowest effects and WOO was most toxic, while the EC50 values of INC show an intermediate toxicity. Among the aquatic tests, daphnids and one algal species were the most sensitive ones, while plants were always more sensitive than earthworms in the solid waste samples. Based on the test results from additional tests proposals for the modification of the existing basic test battery could be made. For example, the earthworm acute test could be replaced by another soil invertebrate test with higher sensitivity. Further work performed in parallel to the ring test improves waste testing considerably (e.g. the use of artificial soil as control substrate). A comparison of the ring test results with literature data published so far revealed a good agreement. The results of this ring test support confirm that a combination of a battery of biological tests and chemical residue analysis is needed for an ecotoxicological characterization of wastes. With small modifications proposed in this report the basic test battery is considered to be well suitable for the hazard and risk assessment of wastes. Further, probably multi-variate evaluation of the ring test results will improve the identification of those tests most qualified for the ecotoxicological characterization of wastes. Finally, the experiences made in the ring test support also the proposals made in CEN guideline 14735 (2005) concerning the performance of such tests. (orig.)

  1. Biological inquiry: a new course and assessment plan in response to the call to transform undergraduate biology.

    Science.gov (United States)

    Goldey, Ellen S; Abercrombie, Clarence L; Ivy, Tracie M; Kusher, Dave I; Moeller, John F; Rayner, Doug A; Smith, Charles F; Spivey, Natalie W

    2012-01-01

    We transformed our first-year curriculum in biology with a new course, Biological Inquiry, in which >50% of all incoming, first-year students enroll. The course replaced a traditional, content-driven course that relied on outdated approaches to teaching and learning. We diversified pedagogical practices by adopting guided inquiry in class and in labs, which are devoted to building authentic research skills through open-ended experiments. Students develop core biological knowledge, from the ecosystem to molecular level, and core skills through regular practice in hypothesis testing, reading primary literature, analyzing data, interpreting results, writing in disciplinary style, and working in teams. Assignments and exams require higher-order cognitive processes, and students build new knowledge and skills through investigation of real-world problems (e.g., malaria), which engages students' interest. Evidence from direct and indirect assessment has guided continuous course revision and has revealed that compared with the course it replaced, Biological Inquiry produces significant learning gains in all targeted areas. It also retains 94% of students (both BA and BS track) compared with 79% in the majors-only course it replaced. The project has had broad impact across the entire college and reflects the input of numerous constituencies and close collaboration among biology professors and students.

  2. Structural and Biological Assessment of Zinc Doped Hydroxyapatite Nanoparticles

    Directory of Open Access Journals (Sweden)

    Cristina Liana Popa

    2016-01-01

    Full Text Available The aim of the current research work was to study the physicochemical and biological properties of synthesized zinc doped hydroxyapatite (ZnHAp nanoparticles with Zn concentrations xZn=0 (HAp, xZn=0.07 (7ZnHAp, and xZn=0.1 (10ZnHAp for potential use in biological applications. The morphology, size, compositions, and incorporation of zinc into hydroxyapatite were characterized by scanning electron microscopy (SEM, transmission electron microscopy (TEM, Fourier Transform Infrared Spectroscopy (FTIR, Raman scattering, and X-Ray Photoelectron Spectroscopy (XPS. In addition, the cytotoxicity of ZnHAp nanoparticles was tested on both E. coli bacteria and human hepatocarcinoma cell line HepG2. The results showed that ZnHAp nanoparticles (HAp, 7ZnHAp, and 10ZnHAp have slightly elongated morphologies with average diameters between 25 nm and 18 nm. On the other hand, a uniform and homogeneous distribution of the constituent elements (calcium, phosphorus, zinc, and oxygen in the ZnHAp powder was noticed. Besides, FTIR and Raman analyses confirmed the proper hydroxyapatite structure of the synthesized ZnHAp nanoparticles with the signature of phosphate, carbonate, and hydroxyl groups. Moreover, it can be concluded that Zn doping at the tested concentrations is not inducing a specific prokaryote or eukaryote toxicity in HAp compounds.

  3. FINAL REPORT ON THE AQUATIC MERCURY ASSESSMENT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, N

    2008-09-30

    In February 2000, the United States Environmental Protection Agency (EPA) Region 4 issued a proposed Total Maximum Daily Load (TMDL) for total mercury in the middle and lower Savannah River. The initial TMDL, which would have imposed a 1 ng/l mercury limit for discharges to the middle/lower Savannah River, was revised to 2.8 ng/l in the final TMDL released in February 2001. The TMDL was intended to protect people from the consumption of contaminated fish, which is the major route of mercury exposure to humans. The most bioaccumulative form of mercury is methylmercury, which is produced in aquatic environments by the action of microorganisms on inorganic mercury. Because of the environmental and economic significance of the mercury discharge limits that would have been imposed by the TMDL, the Savannah River Site (SRS) initiated several studies concerning: (1) mercury in SRS discharges, SRS streams and the Savannah River, (2) mercury bioaccumulation factors for Savannah River fish, (3) the use of clams to monitor the influence of mercury from tributary streams on biota in the Savannah River, and (4) mercury in rainwater falling on the SRS. The results of these studies are presented in detail in this report. The first study documented the occurrence, distribution and variation of total and methylmercury at SRS industrial outfalls, principal SRS streams and the Savannah River where it forms the border with the SRS. All of the analyses were performed using the EPA Method 1630/31 ultra low-level and contaminant-free techniques for measuring total and methylmercury. Total mercury at National Pollutant Discharge Elimination System (NPDES) outfalls ranged from 0.31-604 ng/l with a mean of 8.71 ng/l. Mercury-contaminated groundwater was the source for outfalls with significantly elevated mercury concentrations. Total mercury in SRS streams ranged from 0.95-15.7 ng/l. Mean total mercury levels in the streams varied from 2.39 ng/l in Pen Branch to 5.26 ng/l in Tims Branch

  4. SynTec Final Technical Report: Synthetic biology for Tailored Enzyme cocktails

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Janine [Novozymes, Inc., Davis, CA (United States); Teter, Sarah [Novozymes, Inc., Davis, CA (United States)

    2016-06-30

    Using a novel enzyme screening method inspired by synthetic biology, Novozymes developed new technology under SynTec which allows for more rapidly tailoring of enzyme cocktails. The methodology can be applied to specific feedstocks, and or coupled to address a specific hydrolytic conversion process context. Using combinatorial high throughput screening of libraries of enzyme domains, we can quickly assess which combination of catalytic modules delivers the best performance for a specific condition. To demonstrate the effectiveness of the screening process, we measured performance of the output catalytic cocktail compared to CTec3/HTec3. SynTec benchmark cocktail - blend of Cellic® CTec3 and HTec3. The test substrate was - ammonia fiber expansion pretreated corn stover (AFEX™ PCS).CTec3/HTec3 was assayed at the optimal pH and temperature, and also in the absence of any pH adjustment. The new enzyme cocktail discovered under SynTec was assayed in the absence of any pH adjustment and at the optimal temperature. Conversion is delivered by SynTec enzyme at significant dose reduction relative to CTec3/HTec3 at the controlled pH optimum, and without titrant required to maintain pH, which delivers additional cost savings relative to current state of the art process. In this 2.5 year $4M project, the team delivered an experimental cocktail that significantly outperformed CTec3/HTec3 for a specific substrate, and for specific hydrolysis conditions. As a means of comparing performance improvement delivered per research dollar spent, we note that SynTec delivered a similar performance improvement to the previous award, in a shorter time and with fewer resources than for the previously successful DOE project DECREASE, a 3.5 year, $25M project, though this project focused on a different substrate and used different hydrolysis conditions. The newly implemented technology for rapid sourcing of new cellulases and hemicellulases from nature is an example of Novozymes

  5. Autism: A Review of Biological Bases, Assessment, and Intervention

    Science.gov (United States)

    Volker, Martin A.; Lopata, Christopher

    2008-01-01

    The number of children classified with autism in US schools has risen sharply over the past decade. School psychologists are being called upon with increasing frequency to assist in the identification, assessment, and treatment of these children. The diagnostic complexities and heterogeneity of the disorder make dealing effectively with this…

  6. Assessment of uncertainties in risk analysis of chemical establishments. The ASSURANCE project. Final summary report

    DEFF Research Database (Denmark)

    Lauridsen, K.; Kozine, Igor; Markert, Frank;

    2002-01-01

    This report summarises the results obtained in the ASSURANCE project (EU contract number ENV4-CT97-0627). Seven teams have performed risk analyses for the same chemical facility, an ammonia storage. The EC's Joint Research Centre at Ispra and RisøNational Laboratory co-ordinated the exercise...... on the ranking among the adherents of the probabilistic approach. Breaking down the modelling of both frequencyand consequence assessments into suitably small elements and conducting case studies allowed identifying root causes of uncertainty in the final risk assessments. Large differences were found in both...... the frequency assessments and in the assessment ofconsequences. The report gives a qualitative assessment of the importance to the final calculated risk of uncertainties in assumptions made, in the data and the calculation methods used. This assessment can serve as a guide to areas where, in particular...

  7. A Strategic Initiative in Applied Biological Simulations 01-SI-012 Final Report for FY01 - FY03

    Energy Technology Data Exchange (ETDEWEB)

    Lau, E Y; Venclovas, C; Schwegler, E; Gygi, F; Colvin, M E; Bennion, B J; Barsky, D; Mundy, C; Lightstone, F C; Galli, G; Sawicka, D

    2004-02-16

    The goal of this Strategic Initiative in Applied Computational Biology has been to apply LLNL's expertise in computational simulation to forge a new laboratory core competency in biological simulation. By every measure, this SI has been very successful in this goal. Based on a strong publication record and large number of conference presentations and invited talks, we have built a recognized niche for LLNL in the burgeoning field of computational biology. Further, many of the projects that were previously part of this LDRD are now externally funded based on the research results and expertise developed under this SI. We have created successful collaborations with a number of outside research groups including several joint projects with the new UC Davis/LLNL Comprehensive Cancer Center. In addition to these scientific collaborations, the staff developed on this SI is involved in computational biology program development and advisory roles with other DOE laboratories and DOE Headquarters. Moreover, a number of capabilities and expertise created by this SI are finding use in LLNL programmatic applications. Finally, and most importantly, this SI project has brought to LLNL the human talent on who will be the ensuring the further success of computational biology at this laboratory.

  8. Prospective Technology Assessment of Synthetic Biology: Fundamental and Propaedeutic Reflections in Order to Enable an Early Assessment.

    Science.gov (United States)

    Schmidt, Jan Cornelius

    2016-08-01

    Synthetic biology is regarded as one of the key technosciences of the future. The goal of this paper is to present some fundamental considerations to enable procedures of a technology assessment (TA) of synthetic biology. To accomplish such an early "upstream" assessment of a not yet fully developed technology, a special type of TA will be considered: Prospective TA (ProTA). At the center of ProTA are the analysis and the framing of "synthetic biology," including a characterization and assessment of the technological core. The thesis is that if there is any differentia specifica giving substance to the umbrella term "synthetic biology," it is the idea of harnessing self-organization for engineering purposes. To underline that we are likely experiencing an epochal break in the ontology of technoscientific systems, this new type of technology is called "late-modern technology." -I start this paper by analyzing the three most common visions of synthetic biology. Then I argue that one particular vision deserves more attention because it underlies the others: the vision of self-organization. I discuss the inherent limits of this new type of late-modern technology in the attempt to control and monitor possible risk issues. I refer to Hans Jonas' ethics and his early anticipation of the risks of a novel type of technology. I end by drawing conclusions for the approach of ProTA towards an early societal shaping of synthetic biology.

  9. The Importance of Biologically Relevant Microclimates in Habitat Suitability Assessments

    OpenAIRE

    Johanna Varner; M Denise Dearing

    2014-01-01

    Predicting habitat suitability under climate change is vital to conserving biodiversity. However, current species distribution models rely on coarse scale climate data, whereas fine scale microclimate data may be necessary to assess habitat suitability and generate predictive models. Here, we evaluate disparities between temperature data at the coarse scale from weather stations versus fine-scale data measured in microhabitats required for a climate-sensitive mammal, the American pika (Ochoto...

  10. Assessing the Biological Activity of the Glucan Phosphatase Laforin.

    Science.gov (United States)

    Romá-Mateo, Carlos; Raththagala, Madushi; Gentry, Mathew S; Sanz, Pascual

    2016-01-01

    Glucan phosphatases are a recently discovered family of enzymes that dephosphorylate either starch or glycogen and are essential for proper starch metabolism in plants and glycogen metabolism in humans. Mutations in the gene encoding the only human glucan phosphatase, laforin, result in the fatal, neurodegenerative, epilepsy known as Lafora disease. Here, we describe phosphatase assays to assess both generic laforin phosphatase activity and laforin's unique glycogen phosphatase activity. PMID:27514803

  11. Final report for Conference Support Grant "From Computational Biophysics to Systems Biology - CBSB12"

    Energy Technology Data Exchange (ETDEWEB)

    Hansmann, Ulrich H.E.

    2012-07-02

    This report summarizes the outcome of the international workshop “From Computational Biophysics to Systems Biology (CBSB12)” which was held June 3-5, 2012, at the University of Tennessee Conference Center in Knoxville, TN, and supported by DOE through the Conference Support Grant 120174. The purpose of CBSB12 was to provide a forum for the interaction between a data-mining interested systems biology community and a simulation and first-principle oriented computational biophysics/biochemistry community. CBSB12 was the sixth in a series of workshops of the same name organized in recent years, and the second that has been held in the USA. As in previous years, it gave researchers from physics, biology, and computer science an opportunity to acquaint each other with current trends in computational biophysics and systems biology, to explore venues of cooperation, and to establish together a detailed understanding of cells at a molecular level. The conference grant of $10,000 was used to cover registration fees and provide travel fellowships to selected students and postdoctoral scientists. By educating graduate students and providing a forum for young scientists to perform research into the working of cells at a molecular level, the workshop adds to DOE's mission of paving the way to exploit the abilities of living systems to capture, store and utilize energy.

  12. Final report for Conference Support Grant "From Computational Biophysics to Systems Biology - CBSB12"

    Energy Technology Data Exchange (ETDEWEB)

    Hansmann, Ulrich H.E.

    2012-07-02

    This report summarizes the outcome of the international workshop From Computational Biophysics to Systems Biology (CBSB12) which was held June 3-5, 2012, at the University of Tennessee Conference Center in Knoxville, TN, and supported by DOE through the Conference Support Grant 120174. The purpose of CBSB12 was to provide a forum for the interaction between a data-mining interested systems biology community and a simulation and first-principle oriented computational biophysics/biochemistry community. CBSB12 was the sixth in a series of workshops of the same name organized in recent years, and the second that has been held in the USA. As in previous years, it gave researchers from physics, biology, and computer science an opportunity to acquaint each other with current trends in computational biophysics and systems biology, to explore venues of cooperation, and to establish together a detailed understanding of cells at a molecular level. The conference grant of $10,000 was used to cover registration fees and provide travel fellowships to selected students and postdoctoral scientists. By educating graduate students and providing a forum for young scientists to perform research into the working of cells at a molecular level, the workshop adds to DOE's mission of paving the way to exploit the abilities of living systems to capture, store and utilize energy.

  13. Strategies for Assessment of the Biological Performance and Design of Hydroturbines

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, Thomas J.; Richmond, Marshall C.

    2011-05-05

    The biological response of fish to turbine passage has been of concern for several decades and emphasized recently by consideration of hydro as a 'green' power source. The current state-of-the-art of hydro-turbine biological performance assessment, while still inadequate, has advanced considerably the past 10 years. For example, the importance of assessment of exposure to pressure changes during turbine passage has been emphasized by findings of laboratory studies of rapid decompression. It is now very clear that hydroturbine biological assessment must consider the physiological state and behavior of fish at turbine entry and changes in physiological state that drive aspects of behavior during tailrace passage. Such considerations are in addition to concerns about exposure of fish to mechanical and pressure sources of injury during turbine passage. Experimental designs and assessment tools have evolved for acclimation of test fish, observation of test fish behavior at approach and upon exit from the turbine environment, and precise estimation of turbine passage mortality. Fish condition assessment continues to improve permitting better classification of observed injuries to injury mechanisms. Computational fluid dynamics (CFD) models and other computer models permit detailed investigation of the turbine passage environment and development of hypotheses that can be tested in field studies using live fish. Risk assessment techniques permit synthesis of laboratory and in-field study findings and estimation of population level effects over a wide range of turbine operation scenarios. Risk assessment is also evolving to provide input to turbine runner design. These developments, and others, have resulted in more productive biological performance assessment studies and will continue to evolve and improve the quantity and quality of information obtained from costly live fish hydroturbine passage studies. This paper reviews the history of hydro-turbine biological

  14. Automated extraction of BI-RADS final assessment categories from radiology reports with natural language processing.

    Science.gov (United States)

    Sippo, Dorothy A; Warden, Graham I; Andriole, Katherine P; Lacson, Ronilda; Ikuta, Ichiro; Birdwell, Robyn L; Khorasani, Ramin

    2013-10-01

    The objective of this study is to evaluate a natural language processing (NLP) algorithm that determines American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) final assessment categories from radiology reports. This HIPAA-compliant study was granted institutional review board approval with waiver of informed consent. This cross-sectional study involved 1,165 breast imaging reports in the electronic medical record (EMR) from a tertiary care academic breast imaging center from 2009. Reports included screening mammography, diagnostic mammography, breast ultrasound, combined diagnostic mammography and breast ultrasound, and breast magnetic resonance imaging studies. Over 220 reports were included from each study type. The recall (sensitivity) and precision (positive predictive value) of a NLP algorithm to collect BI-RADS final assessment categories stated in the report final text was evaluated against a manual human review standard reference. For all breast imaging reports, the NLP algorithm demonstrated a recall of 100.0 % (95 % confidence interval (CI), 99.7, 100.0 %) and a precision of 96.6 % (95 % CI, 95.4, 97.5 %) for correct identification of BI-RADS final assessment categories. The NLP algorithm demonstrated high recall and precision for extraction of BI-RADS final assessment categories from the free text of breast imaging reports. NLP may provide an accurate, scalable data extraction mechanism from reports within EMRs to create databases to track breast imaging performance measures and facilitate optimal breast cancer population management strategies. PMID:23868515

  15. Sequential chemical-biological processes for the treatment of industrial wastewaters: review of recent progresses and critical assessment.

    Science.gov (United States)

    Guieysse, Benoit; Norvill, Zane N

    2014-02-28

    When direct wastewater biological treatment is unfeasible, a cost- and resource-efficient alternative to direct chemical treatment consists of combining biological treatment with a chemical pre-treatment aiming to convert the hazardous pollutants into more biodegradable compounds. Whereas the principles and advantages of sequential treatment have been demonstrated for a broad range of pollutants and process configurations, recent progresses (2011-present) in the field provide the basis for refining assessment of feasibility, costs, and environmental impacts. This paper thus reviews recent real wastewater demonstrations at pilot and full scale as well as new process configurations. It also discusses new insights on the potential impacts of microbial community dynamics on process feasibility, design and operation. Finally, it sheds light on a critical issue that has not yet been properly addressed in the field: integration requires complex and tailored optimization and, of paramount importance to full-scale application, is sensitive to uncertainty and variability in the inputs used for process design and operation. Future research is therefore critically needed to improve process control and better assess the real potential of sequential chemical-biological processes for industrial wastewater treatment.

  16. Third international conference on intelligent systems for molecular biology (ISMB-95): Summary. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The specific aims of the Third International Conference on Intelligent Systems for Molecular Biology (ISMB-95) were to: convene a critical mass of researchers applying advanced computational techniques to problems in molecular biology; promote interchange of problems and solutions between computer scientists and molecular biologists; create education opportunities in this cross-disciplinary field for students and senior researchers wishing to either apply or benefit from these techniques; produce an archival proceedings as a forum for rapid dissemination of new results in a peer-reviewed manner; produce a set of tutorial materials for education and training of researchers interested in this field; maintain the momentum generated by the highly successful previous conferences in the series, and establish a regular event that will help to solidify the field; and foster the involvement of women and minorities in the field.

  17. Biological and chemical assessments of zinc ageing in field soils

    International Nuclear Information System (INIS)

    As zinc (Zn) is both an essential trace element and potential toxicant, the effects of Zn fixation in soil are of practical significance. Soil samples from four field sites amended with ZnSO4 were used to investigate ageing of soluble Zn under field conditions over a 2-year period. Lability of Zn measured using 65Zn radioisotope dilution showed a significant decrease over time and hence evidence of Zn fixation in three of the four soils. However, 0.01 M CaCl2 extractions and toxicity measurements using a genetically modified lux-marked bacterial biosensor did not indicate a decrease in soluble/bioavailable Zn over time. This was attributed to the strong regulatory effect of abiotic properties such as pH on these latter measurements. These results also showed that Zn ageing occurred immediately after Zn spiking, emphasising the need to incubate freshly spiked soils before ecotoxicity assessments. - Ageing effects were detected in Zn-amended field soils using 65Zn isotopic dilution as a measure of lability, but not with either CaCl2 extractions or a lux-marked bacterial biosensor.

  18. Research and engineering assessment of biological solubilization of phosphate

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, R.D.; McIlwain, M.E.; Losinski, S.J.; Taylor, D.D.

    1993-03-01

    This research and engineering assessment examined a microbial phosphate solubilization process as a method of recovering phosphate from phosphorus containing ore compared to the existing wet acid and electric arc methods. A total of 860 microbial isolates, collected from a range of natural environments were tested for their ability to solubilize phosphate from rock phosphate. A bacterium (Pseudomonas cepacia) was selected for extensive characterization and evaluation of the mechanism of phosphate solubilization and of process engineering parameters necessary to recover phosphate from rock phosphate. These studies found that concentration of hydrogen ion and production of organic acids arising from oxidation of the carbon source facilitated microbial solubilization of both pure chemical insoluble phosphate compounds and phosphate rock. Genetic studies found that phosphate solubilization was linked to an enzyme system (glucose dehydrogenase). Process-related studies found that a critical solids density of 1% by weight (ore to liquid) was necessary for optimal solubilization. An engineering analysis evaluated the cost and energy requirements for a 2 million ton per year sized plant, whose size was selected to be comparable to existing wet acid plants.

  19. Quality of environmental impact assessment (EIA) reports on biological pest control / Thea Henriette Carroll

    OpenAIRE

    Carroll, Thea Henriette

    2006-01-01

    Decision making regarding the release of biological control agents for invasive species such as lantana, Lantana camara, requires the consideration and evaluation of environmental impact assessment (EIA) reports by a competent authority. Although various biological control agents have been authorised for release into the environment for the control of lantana, the quality of the EIA reports that form the basis for decision making has never been evaluated. The evaluation of the ...

  20. Lake Whitney Comprehensive Water Quality Assessment, Phase 1B- Physical and Biological Assessment (USDOE)

    Energy Technology Data Exchange (ETDEWEB)

    Doyle, Robert D; Byars, Bruce W

    2009-11-24

    Baylor University Center for Reservoir and Aquatic Systems Research (CRASR) has conducted a phased, comprehensive evaluation of Lake Whitney to determine its suitability for use as a regional water supply reservoir. The area along the Interstate 35 corridor between Dallas / Fort Worth Metroplex and the Waco / Temple Centroplex represents one of the fastest growth areas in the State of Texas and reliable water supplies are critical to sustainable growth. Lake Whitney is situated midway between these two metropolitan areas. Currently, the City of Whitney as well as all of Bosque and Hill counties obtain their potable water from the Trinity Sands aquifer. Additionally, parts of the adjoining McLennan and Burleson counties utilize the Trinity sands aquifer system as a supplement to their surface water supplies. Population growth coupled with increasing demands on this aquifer system in both the Metroplex and Centroplex have resulted in a rapid depletion of groundwater in these rural areas. The Lake Whitney reservoir represents both a potentially local and regional solution for an area experiencing high levels of growth. Because of the large scope of this project as well as the local, regional and national implications, we have designed a multifaceted approach that will lead to the solution of numerous issues related to the feasibility of using Lake Whitney as a water resource to the region. Phase IA (USEPA, QAPP Study Elements 1-4) of this research focused on the physical limnology of the reservoir (bathymetry and fine scale salinity determination) and develops hydrodynamic watershed and reservoir models to evaluate how salinity would be expected to change with varying hydrologic and climatic factors. To this end, we implemented a basic water quality modeling program in collaboration with the Texas Parks and Wildlife Department and the Texas Commission on Environmental Quality to add to the developing long-term database on Lake Whitney. Finally, we conducted an initial

  1. A Biological Condition Gradient Model for Historical Assessment of Estuarine Habitat Structure

    Science.gov (United States)

    Shumchenia, Emily J.; Pelletier, Marguerite C.; Cicchetti, Giancarlo; Davies, Susan; Pesch, Carol E.; Deacutis, Christopher F.; Pryor, Margherita

    2015-01-01

    Coastal ecosystems are affected by ever-increasing natural and human pressures. Because the physical, chemical, and biological characteristics unique to estuarine ecosystems control the ways that biological resources respond to ecosystem stressors, we present a flexible and adaptable biological assessment method for estuaries. The biological condition gradient (BCG) is a scientific framework of biological response to increasing anthropogenic stress that is comprehensive and ecosystem based and evaluates environmental conditions and the status of ecosystem services in order to identify, communicate, and prioritize management action. Using existing data, we constructed the first estuarine BCG framework that examines changes in habitat structure through time. Working in a New England (U.S.) estuary with a long history of human influence, we developed an approach to define a reference level, which we described as a "minimally disturbed" range of conditions for the ecosystem, anchored by observations before 1850 AD. Like many estuaries in the U.S., the relative importance of environmental stressors changed over time, but even qualitative descriptions of the biological indicators' status provided useful information for defining condition levels. This BCG demonstrated that stressors rarely acted alone and that declines in one biological indicator influenced the declines of others. By documenting the biological responses to cumulative stressors, the BCG inherently suggests an ecosystem-based approach to management. Additionally, the BCG process initiates thinking over long time scales and can be used to inspire scientists, managers, and the public toward environmental action.

  2. Enzymology of biological nitrogen fixation. Final report, May 1, 1987--April 30, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    Biological nitrogen fixation is of central importance in the earth`s nitrogen economy. Fixation of nitrogen is accomplished by a variety of microorganisms, all of them procaryotic. Some operate independently and some function symbiotically or associatively with photosynthesizing plants. Biological nitrogen fixation is accomplished via the reaction: N{sub 2} + 8H{sup +} + 8e{sup {minus}} {yields} 2NH{sub 3} + H{sub 2}. This reaction requires a minimum of 16 ATP under ideal laboratory conditions, so it is obvious that the energy demand of the reaction is very high. When certain nitrogen-fixing organisms are supplied fixed nitrogen (e.g., ammonium) the organisms use the fixed nitrogen and turn off their nitrogenase system, thus conserving energy. When the fixed nitrogen is exhausted, the organism reactivates its nitrogenase. The system is turned off by dinitrogenase reductase ADP-ribosyl transferase (DRAT) and turned back on by dinitrogenase reductase-activating glycohydrolase (DRAG). The authors have investigated the details of how DRAT and DRAG are formed, how they function, and the genetics of their formation and operation.

  3. Development of the Final Version of the Classification and Assessment of Occupational Dysfunction Scale

    OpenAIRE

    Mutsumi Teraoka; Makoto Kyougoku

    2015-01-01

    Occupational therapy is involved in disability prevention and health enhancement through the prevention of occupational dysfunction. Although many occupational dysfunction scales exist, no standard method is available for the assessment and classification of occupational dysfunction, which may include occupational imbalance, occupational deprivation, occupational alienation, and occupational marginalization. The purpose of this study was to develop the final version of Classification and Asse...

  4. 76 FR 30639 - Final Environmental Assessment and Mitigated Finding of No Significant Impact; Giant Miscanthus...

    Science.gov (United States)

    2011-05-26

    ... on April 8, 2011 (76 FR 19741) and used additional inputs from the Natural Resources Conservation... on October 27, 2010 (75 FR 65995-66007) is incorporated by reference in the EA. FSA considered the... Commodity Credit Corporation Farm Service Agency Final Environmental Assessment and Mitigated Finding of...

  5. Development of the Neuron Assessment for Measuring Biology Students’ Use of Experimental Design Concepts and Representations

    Science.gov (United States)

    Dasgupta, Annwesa P.; Anderson, Trevor R.; Pelaez, Nancy J.

    2016-01-01

    Researchers, instructors, and funding bodies in biology education are unanimous about the importance of developing students’ competence in experimental design. Despite this, only limited measures are available for assessing such competence development, especially in the areas of molecular and cellular biology. Also, existing assessments do not measure how well students use standard symbolism to visualize biological experiments. We propose an assessment-design process that 1) provides background knowledge and questions for developers of new “experimentation assessments,” 2) elicits practices of representing experiments with conventional symbol systems, 3) determines how well the assessment reveals expert knowledge, and 4) determines how well the instrument exposes student knowledge and difficulties. To illustrate this process, we developed the Neuron Assessment and coded responses from a scientist and four undergraduate students using the Rubric for Experimental Design and the Concept-Reasoning Mode of representation (CRM) model. Some students demonstrated sound knowledge of concepts and representations. Other students demonstrated difficulty with depicting treatment and control group data or variability in experimental outcomes. Our process, which incorporates an authentic research situation that discriminates levels of visualization and experimentation abilities, shows potential for informing assessment design in other disciplines. PMID:27146159

  6. Development of the Neuron Assessment for Measuring Biology Students' Use of Experimental Design Concepts and Representations.

    Science.gov (United States)

    Dasgupta, Annwesa P; Anderson, Trevor R; Pelaez, Nancy J

    2016-01-01

    Researchers, instructors, and funding bodies in biology education are unanimous about the importance of developing students' competence in experimental design. Despite this, only limited measures are available for assessing such competence development, especially in the areas of molecular and cellular biology. Also, existing assessments do not measure how well students use standard symbolism to visualize biological experiments. We propose an assessment-design process that 1) provides background knowledge and questions for developers of new "experimentation assessments," 2) elicits practices of representing experiments with conventional symbol systems, 3) determines how well the assessment reveals expert knowledge, and 4) determines how well the instrument exposes student knowledge and difficulties. To illustrate this process, we developed the Neuron Assessment and coded responses from a scientist and four undergraduate students using the Rubric for Experimental Design and the Concept-Reasoning Mode of representation (CRM) model. Some students demonstrated sound knowledge of concepts and representations. Other students demonstrated difficulty with depicting treatment and control group data or variability in experimental outcomes. Our process, which incorporates an authentic research situation that discriminates levels of visualization and experimentation abilities, shows potential for informing assessment design in other disciplines. PMID:27146159

  7. Biologic

    CERN Document Server

    Kauffman, L H

    2002-01-01

    In this paper we explore the boundary between biology and the study of formal systems (logic). In the end, we arrive at a summary formalism, a chapter in "boundary mathematics" where there are not only containers but also extainers ><, entities open to interaction and distinguishing the space that they are not. The boundary algebra of containers and extainers is to biologic what boolean algebra is to classical logic. We show how this formalism encompasses significant parts of the logic of DNA replication, the Dirac formalism for quantum mechanics, formalisms for protein folding and the basic structure of the Temperley Lieb algebra at the foundations of topological invariants of knots and links.

  8. Biological Ocean Margins Program. Active Microbes Responding to Inputs from the Orinoco River Plume. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Jorge E. Corredor

    2013-01-28

    The overall goal of the proposed work is to identify the active members of the heterotrophic community involved in C and N cycling in the perimeter of the Orinoco River Plume (ORP), assess their spatial distribution, quantify their metabolic activity, and correlate these parameters to plume properties such as salinity, organic matter content and phytoplankton biomass.

  9. E-Portfolios Rescue Biology Students from a Poorer Final Exam Result: Promoting Student Metacognition

    Science.gov (United States)

    Haave, Neil

    2016-01-01

    E-portfolios have the potential to transform students' learning experiences. They promote reflection on the significance of what and how students have learned. Such reflective practices enhance students' ability to articulate their knowledge and skills to their peers, teachers, and future employers. In addition, e-portfolios can help assess the…

  10. Biological effects of anthropogenic chemical stress: Tools for the assessment of ecosystem health (BEAST)

    DEFF Research Database (Denmark)

    Lehtonen, Kari K.; Sundelin, Brita; Lang, Thomas;

    In the Baltic Sea Action Plan the urgent need to develop biological effects monitoring of hazardous substances and the assessment of ecosystem health has been clearly indicated. These goals will be tackled in the newly launched BEAST project (Biological Effects of Anthropogenic Chemical Stress......: Tools for the Assessment of Ecosystem Health, 2009-2011), which is part of the Baltic Sea BONUS+ Programme funded jointly by national funding agencies and FP7 ERA-NET+ of the European Commission. The BEAST project consists of three workpackages (WP) with the following main tasks: WP1- Field studies and...... experiments in selected sub-regions of the Baltic Sea, WP2 - Application and validation of methods in monitoring and assessment in the Baltic Sea, and WP3 - Developing tools for ecosystem health assessment in the Baltic Sea. BEAST research activities are focused in the sub-regions of Gulf of Bothnia, Gulf of...

  11. Biological and clinical dosimetry, July 1, 1964 to December 31, 1984. Final report

    International Nuclear Information System (INIS)

    The goal was to develop systems for the determination of absorbed dose in biological research and clinical applications. The primary method under study is the local absorbed dose calorimeter. In addition, secondary dosimetric systems such as ionization chambers, chemical dosimeters and thermoluminescent dosimeters (TLD) are being developed and applied to provide an absolute basis for the evaluation and comparison of experiments, treatments and other procedures using radiation. In keeping with these objectives this project has accomplished significant advances in the following areas: (1) local absorbed dose calorimetry; (2) neutron dosimetry; (3) dosimetry of ultra-high intensity radiation sources; (4) solid state detector and germanium gamma camera program; (5) dosimetry for brachytherapy; and (6) ''non-isolated sensor'' calorimeters

  12. Final Report - Phylogenomic tools and web resources for the Systems Biology Knowledgebase

    Energy Technology Data Exchange (ETDEWEB)

    Sjolander, Kimmen [Univ. of California, Berkeley, CA (United States)

    2014-12-08

    The major advance during this last reporting period (8/15/12 to present) is our release of data on the PhyloFacts website: phylogenetic trees, multiple sequence alignments and other data for protein families are now available for download from http://phylogenomics.berkeley.edu/data/. This project as a whole aimed to develop high-throughput functional annotation systems that exploit information from protein 3D structure and evolution to provide highly precise inferences of various aspects of gene function, including molecular function, biological process, pathway association, Pfam domains, cellular localization and so on. We accomplished these aims by developing and testing different systems on a database of protein family trees: the PhyloFacts Phylogenomic Encyclopedia (at http://phylogenomics.berkeley.edu/phylofacts/ ).

  13. Final LDRD report : development of advanced UV light emitters and biological agent detection strategies.

    Energy Technology Data Exchange (ETDEWEB)

    Figiel, Jeffrey James; Crawford, Mary Hagerott; Banas, Michael Anthony; Farrow, Darcie; Armstrong, Andrew M.; Serkland, Darwin Keith; Allerman, Andrew Alan; Schmitt, Randal L.

    2007-12-01

    We present the results of a three year LDRD project which has focused on the development of novel, compact, ultraviolet solid-state sources and fluorescence-based sensing platforms that apply such devices to the sensing of biological and nuclear materials. We describe our development of 270-280 nm AlGaN-based semiconductor UV LEDs with performance suitable for evaluation in biosensor platforms as well as our development efforts towards the realization of a 340 nm AlGaN-based laser diode technology. We further review our sensor development efforts, including evaluation of the efficacy of using modulated LED excitation and phase sensitive detection techniques for fluorescence detection of bio molecules and uranyl-containing compounds.

  14. Postmarketing safety reports for human drug and biological products; electronic submission requirements. Final rule.

    Science.gov (United States)

    2014-06-10

    The Food and Drug Administration (FDA or we) is amending its postmarketing safety reporting regulations for human drug and biological products to require that persons subject to mandatory reporting requirements submit safety reports in an electronic format that FDA can process, review, and archive. FDA is taking this action to improve the Agency's systems for collecting and analyzing postmarketing safety reports. The change will help the Agency to more rapidly review postmarketing safety reports, identify emerging safety problems, and disseminate safety information in support of FDA's public health mission. In addition, the amendments will be a key element in harmonizing FDA's postmarketing safety reporting regulations with international standards for the electronic submission of safety information.

  15. Final Report - Phylogenomic tools and web resources for the Systems Biology Knowledgebase

    Energy Technology Data Exchange (ETDEWEB)

    Sjolander, Kimmen

    2014-11-07

    The major advance during this last reporting period (8/15/12 to present) is our release of data on the PhyloFacts website: phylogenetic trees, multiple sequence alignments and other data for protein families are now available for download from http://phylogenomics.berkeley.edu/data/. This project as a whole aimed to develop high-throughput functional annotation systems that exploit information from protein 3D structure and evolution to provide highly precise inferences of various aspects of gene function, including molecular function, biological process, pathway association, Pfam domains, cellular localization and so on. We accomplished these aims by developing and testing different systems on a database of protein family trees: the PhyloFacts Phylogenomic Encyclopedia (at http://phylogenomics.berkeley.edu/phylofacts/ ).

  16. COMPARISON OF TWO BIOLOGICAL METHODS FOR ASSESSMENT OF RIVER WATER QUALITY BASED ON MACROZOOBENTHOS

    OpenAIRE

    Mladen Kerovec; Zlatko Mihaljević

    2010-01-01

    In the present paper, the results of two macrozoobenthos analysis based indices (Saprobic Index and Extended Biotic Index) are used as biological indicators in the assessment of river water quality. The objective of the paper is to establish the extent to which the results of these methods are comparable. The results indicate that both indices are suitable for assessing the quality of river water in the Croatian hydrographic network. Major deviations were only detected in xenosaprobic waters,...

  17. Biologic considerations in anatomic imaging with radionuclides. Final progress report, July 1974--June 1975

    International Nuclear Information System (INIS)

    An important task relating to anatomic imaging with radionuclides is the determination of factors which effect the use of imaging procedures. This is important to reduce radiation exposure in the population, to improve the efficacy of diagnostic imaging procedures and finally to provide a basis for evaluating the potential effects of proposed regulation of use rates. In this report we describe a methodology for obtaining clinical data relating to the use of the brain scan in an inner city teaching hospital. The development of a questionnaire suitable for use in a clinical setting and providing both prospective and retrospective data is presented. The results of the use of the questionnaire at the Johns Hopkins Hospital during a three month period in 1974 are shown and discussed. Some preliminary results from these data are given and a method for further analysis is indicated

  18. Risk assessment and stakeholder perceptions in novel biological control agent release: YST as a case study

    Science.gov (United States)

    The objectives of risk assessment are to learn about whether a candidate agent would be safe to use in the environment where release is planned, and to present such information in a clear, understandable format to regulators, stakeholders, and the public. Plant pathogens evaluated for biological co...

  19. Biohorizons: An eConference to Assess Human Biology in Large, First-Year Classes

    Science.gov (United States)

    Moni, Roger W.; Moni, Karen B.; Poronnik, Philip; Lluka, Lesley J.

    2007-01-01

    The authors detail the design, implementation and evaluation of an eConference entitled "Biohorizons," using a presage-process-product model to describe the development of an eLearning community. Biohorizons was a summative learning and assessment task aiming to introduce large classes of first-year Human Biology students to the practices of…

  20. 75 FR 28232 - Availability of an Environmental Assessment for a Biological Control Agent for Hemlock Woolly...

    Science.gov (United States)

    2010-05-20

    ... Control Agent for Hemlock Woolly Adelgid AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION... Plant Health Inspection Service has prepared an environmental assessment relative to the control of... a biological control agent to reduce the severity of hemlock woolly adelgid infestations. We...

  1. 77 FR 46373 - Availability of an Environmental Assessment for a Biological Control Agent for Hemlock Woolly...

    Science.gov (United States)

    2012-08-03

    ... Control Agent for Hemlock Woolly Adelgid AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION... prepared an environmental assessment relative to the release of Symnus coniferarum to control hemlock... of Symnus coniferarum into the eastern United States for use as a biological control agent to...

  2. Biological assessment for the effluent reduction program, Los Alamos National Laboratory, Los Alamos, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Cross, S.P.

    1996-08-01

    This report describes the biological assessment for the effluent recution program proposed to occur within the boundaries of Los Alamos National Laboratory. Potential effects on wetland plants and on threatened and endangered species are discussed, along with a detailed description of the individual outfalls resulting from the effluent reduction program.

  3. Biological conversion of synthesis gas. Final report, August 31, 1990--September 3, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Basu, R.; Klasson, K.T.; Johnson, E.R.; Takriff, M.; Clausen, E.C.; Gaddy, J.L.

    1993-09-01

    Based upon the results of this culture screening study, Rhodospirillum rubrum is recommended for biocatalysis of the water gas shift reaction and Chlorobium thiosulfatophilum is recommended for H{sub 2}S conversion to elemental sulfur. Both bacteria require tungsten light for growth and can be co-cultured together if H{sub 2}S conversion is not complete (required concentration of at least 1 ppM), thereby presenting H{sub 2} uptake by Chlorobium thiosulfatophilum. COS degradation may be accomplished by utilizing various CO-utilizing bacteria or by indirectly converting COS to elemental sulfur after the COS first undergoes reaction to H{sub 2} in water. The second alternative is probably preferred due to the low expected concentration of COS relative to H{sub 2}S. Mass transfer and kinetic studies were carried out for the Rhodospirillum rubrum and Chlorobium thiosulfatophilum bacterial systems. Rhodospirillum rubrum is a photosynthetic anaerobic bacterium which catalyzes the biological water gas shift reaction: CO + H{sub 2}O {yields} CO{sub 2} + H{sub 2}. Chlorobium thiosulfatophilum is also a photosynthetic anaerobic bacteria, and converts H{sub 2}S and COS to elemental sulfur.

  4. A biological/chemical process for reduced waste and energy consumption: caprolactam production. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    A biological/chemical process for converting cyclohexane into caprolactam was investigated: microorganisms in a bioreactor would be used to convert cyclohexane into caprolactone followed by chemical synthesis of caprolactam using ammonia. Four microorganisms were isolated from natural soil and water, that can utilize cyclohexane as a sole source of C and energy for growth. They were shown to have the correct metabolic intermediates and enzymes to convert cyclohexane into cyclohexanol, cyclohexanone, and caprolactone. Genetic techniques to create and select for caprolactone hydrolase negative-mutants were developed; those are used to convert cyclohexane into caprolactone but, because of the block, are unable to metabolize the caprolactone further. Because of a new nylon carpet reycle process and the long time frame for a totally new bioprocess, a limited study was done to evaluate whether a simplified bioprocess to convert cyclohexanol into cyclohexanone or caprolactone was feasible; growth rates and key enzyme levels were measured in a collection of microorganisms that metabolize cyclohexanol to determine if the bioactivity is high enough to support an economical cyclohexanol bioprocess. Although these microorganisms had sufficient bioactivity, they could tolerate only low levels (<1%) of cyclohexanol and thus are not suitable for developing a cost effective bioprocess because of the high cost of dilute product recovery.

  5. Dispersed oil toxicity tests with biological species indigenous to the Gulf of Mexico. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Fucik, K.W.; Carr, K.A.; Balcom, B.J.

    1994-08-01

    Static and flowthrough aquatic acute toxicity testing protocols were utilized on eggs and larvae of seven commercially important invertebrates and fishes from the Gulf of Mexico. Test organisms were exposed to Central and Western Gulf oils, dispersed oil, and Corexit 9527. Species included brown shrimp (Penaeus aztecus), white shrimp (Penaeus setiferus), blue crab (Callinectes sapidus), eastern oyster (Crassostrea virginica), red drum (Sciaenops ocellatus), inland silverside (Menidia berylina), and spot (Leiosomus xanthurus). Atlantic menhaden (Brevoortia tyrannus) was also tested because gulf menhaden were not available. Mysids (Mysidopsis bahia) were evaluated as part of a chronic toxicity assessment.

  6. Retrospective Review on the Final Assessment Categorization of the Suspicious Microcalcifications

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Hun; Park, Mi Jung; Yim, Hyeon Woo [Catholic University, Seoul (Korea, Republic of); Lee, Jae Hee [Human Medical Imaging and Intervention Center, Seoul (Korea, Republic of); Choi, Bo Bae [Chungnam University Hospital, Daejeon (Korea, Republic of)

    2009-02-15

    The ACR BI-RADS 4th edition provides little guidance on how to classify microcalcifications depicted on mammogram into final assessment categories. We retrospectively evaluated whether our categorization could predict the probability of malignancy, based on histopathology and imaging follow-up. From 2004 to 2005, 83 women who underwent image-guided biopsy for suspicious microcalcifications were subjected. Each lesion was classified by the final assessment categories as category 3 (probably benign finding), category 4A (low suspicion of malignancy), category 4BC (intermediate to moderate suspicion of malignancy), and category 5 (highly suggestive of malignancy) according to our criteria. The positive predictive value (PPV) of each category was assessed. The final assessment categories were category 3 in 4 cases (4.8%), category 4A in 40 cases (48.1%), category 4BC in 31 cases (37.3%), and category 5 in 8 cases (9.6%). The PPVs for malignancy were 0% in C3, 7.5% in C4A, 64.5% in C4BC and 87.5% in C5. Our categorization correlated well with the suggested probability of malignancy in the BI-RADS. It is thought that the application of the subcategories, 4A and 4BC, is of help to stratify the probability of malignancy of lesions requiring biopsy

  7. Hawaii Geothermal Resource Assessment Program: western state cooperative direct heat resource assessment, Phase I. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    A regional geothermal resource assessment has been conducted for the major islands in the Hawaiian chain. The assessment was made through the compilation and evaluation of the readily accessible geological, geochemical, and geophysical data for the Hawaiian archipelago which has been acquired during the last two decades. The geologic criteria used in the identification of possible geothermal reservoirs were: age and location of most recent volcanism on the island and the geologic structure of each island. The geochemical anomalies used as traces for geothermally altered ground water were: elevated silica concentrations and elevated chloride/magnesium ion ratios. Geophysical data used to identify subsurface structure which may have geothermal potential were: aeromagnetic anomalies, gravity anomalies, and higher than normal well and basal spring discharge temperatures. Geophysical and geochemical anomalies which may be the result of subsurface thermal effects have been identified on the islands of Hawaii, Maui, Molokai and Oahu.

  8. Integrated assessment of oil pollution using biological monitoring and chemical fingerprinting.

    Science.gov (United States)

    Lewis, Ceri; Guitart, Carlos; Pook, Chris; Scarlett, Alan; Readman, James W; Galloway, Tamara S

    2010-06-01

    A full assessment of the impact of oil and chemical spills at sea requires the identification of both the polluting chemicals and the biological effects they cause. Here, a combination of chemical fingerprinting of surface oils, tissue residue analysis, and biological effects measures was used to explore the relationship between spilled oil and biological impact following the grounding of the MSC Napoli container ship in Lyme Bay, England in January 2007. Initially, oil contamination remained restricted to a surface slick in the vicinity of the wreck, and there was no chemical evidence to link biological impairment of animals (the common limpet, Patella vulgata) on the shore adjacent to the oil spill. Secondary oil contamination associated with salvage activities in July 2007 was also assessed. Chemical analyses of aliphatic hydrocarbons and terpanes in shell swabs taken from limpet shells provided an unequivocal match with the fuel oil carried by the ship. Corresponding chemical analysis of limpet tissues revealed increased concentrations of polycyclic aromatic hydrocarbons (PAHs) dominated by phenanthrene and C1 to C3 phenanthrenes with smaller contributions from heavier molecular weight PAHs. Concurrent ecotoxicological tests indicated impairment of cellular viability (p oiled animals. These results illustrate the value of combining biological monitoring with chemical fingerprinting for the rapid identification of spilled oils and their sublethal impacts on biota in situ.

  9. Biological assessment of remedial action at the abandoned uranium mill tailings site near Naturita, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Pursuant to the Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, the U.S. Department of Energy (DOE) is proposing to conduct remedial action to clean up the residual radioactive materials (RRM) at the Naturita uranium processing site in Colorado. The Naturita site is in Montrose County, Colorado, and is approximately 2 miles (mi) (3 kilometer [km]) from the unincorporated town of Naturita. The proposed remedial action is to remove the RRM from the Naturita site to the Upper Burbank Quarry at the Uravan disposal site. To address the potential impacts of the remedial action on threatened and endangered species, the DOE prepared this biological assessment. Informal consultations with the U.S. Department of the Interior, Fish and Wildlife Service (FWS) were initiated in 1986, and the FWS provided a list of the threatened and endangered species that may occur in the Naturita study area. This list was updated by two FWS letters in 1988 and by verbal communication in 1990. A biological assessment was included in the environmental assessment (EA) of the proposed remedial action that was prepared in 1990. This EA addressed the impacts of moving the Naturita RRM to the Dry Flats disposal site. In 1993, the design for the Dry Flats disposal alternative was changed. The FWS was again consulted in 1993 and provided a new list of threatened and endangered species that may occur in the Naturita study area. The Naturita EA and the biological assessment were revised in response to these changes. In 1994, remedial action was delayed because an alternate disposal site was being considered. The DOE decided to move the FIRM at the Naturita site to the Upper Burbank Quarry at the Uravan site. Due to this delay, the FWS was consulted in 1995 and a list of threatened and endangered species was provided. This biological assessment is a revision of the assessment attached to the Naturita EA and addresses moving the Naturita RRM to the Upper Burbank Quarry disposal site.

  10. Overview of BioCreAtIvE: critical assessment of information extraction for biology

    Directory of Open Access Journals (Sweden)

    Hirschman Lynette

    2005-05-01

    Full Text Available Abstract Background The goal of the first BioCreAtIvE challenge (Critical Assessment of Information Extraction in Biology was to provide a set of common evaluation tasks to assess the state of the art for text mining applied to biological problems. The results were presented in a workshop held in Granada, Spain March 28–31, 2004. The articles collected in this BMC Bioinformatics supplement entitled "A critical assessment of text mining methods in molecular biology" describe the BioCreAtIvE tasks, systems, results and their independent evaluation. Results BioCreAtIvE focused on two tasks. The first dealt with extraction of gene or protein names from text, and their mapping into standardized gene identifiers for three model organism databases (fly, mouse, yeast. The second task addressed issues of functional annotation, requiring systems to identify specific text passages that supported Gene Ontology annotations for specific proteins, given full text articles. Conclusion The first BioCreAtIvE assessment achieved a high level of international participation (27 groups from 10 countries. The assessment provided state-of-the-art performance results for a basic task (gene name finding and normalization, where the best systems achieved a balanced 80% precision / recall or better, which potentially makes them suitable for real applications in biology. The results for the advanced task (functional annotation from free text were significantly lower, demonstrating the current limitations of text-mining approaches where knowledge extrapolation and interpretation are required. In addition, an important contribution of BioCreAtIvE has been the creation and release of training and test data sets for both tasks. There are 22 articles in this special issue, including six that provide analyses of results or data quality for the data sets, including a novel inter-annotator consistency assessment for the test set used in task 2.

  11. Models of risk assessments for biologicals or related products in the European Union.

    Science.gov (United States)

    Moos, M

    1995-12-01

    In the context of veterinary biologicals, environmental risk assessment means the evaluation of the risk to human health and the environment (which includes plants and animals) connected with the release of such products. The following categories or types of veterinary biologicals can be distinguished: non-genetically modified organisms (non-GMOs) (inactivated/live) GMOs (inactivated/live) carrier products related products (e.g. non-specific "inducers'). Suitable models used in risk assessment for these products should aim to identify all possible adverse effects. A good working model should lead, at least, to a qualitative judgement on the environmental risk of the biological product (e.g. negligible, low, medium, severe, unacceptable). Quantifiable outcomes are rare; therefore, the producer of a biological product and the European control authorities should accept only models which are based on testable points and which are relevant to the type of product and its instructions for use. In view of animal welfare aspects, models working without animals should be preferred. In recent years, some of these methods have been integrated into safety tests described in European Union Directives and in monographs of the European Pharmacopoeia. By reviewing vaccine/registration problems (e.g. Aujeszky's disease live vaccine for pigs, and vaccinia-vectored rabies vaccine), several models used in risk assessment are demonstrated and discussed. PMID:8639943

  12. Assessing middle school students` understanding of science relationships and processes: Year 2 - instrument validation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Schau, C.; Mattern, N.; Weber, R.; Minnick, K.

    1997-01-01

    Our overall purpose for this multi-year project was to develop an alternative assessment format measuring rural middle school students understanding of science concepts and processes and the interrelationships among them. This kind of understanding is called structural knowledge. We had 3 major interrelated goals: (1) Synthesize the existing literature and critically evaluate the actual and potential use of measures of structural knowledge in science education. (2) Develop a structural knowledge alternative assessment format. (3) Examine the validity of our structural knowledge format. We accomplished the first two goals during year 1. The structural knowledge assessment we identified and developed further was a select-and-fill-in concept map format. The goal for our year 2 work was to begin to validate this assessment approach. This final report summarizes our year 2 work.

  13. DARWIN Y LA IMPOSIBILIDAD DE CAUSAS FINALES EN LA BIOLOGÍA Darwin and the Impossibility of Final Causes in Biology

    Directory of Open Access Journals (Sweden)

    ÁLVARO CORRAL CUARTAS

    Full Text Available La teoría de la selección natural propuesta por Charles Darwin en su obra El origen de las especies no solo colocó las bases para una explicación coherente de los hechos fundamentales de la biología (el origen común de los seres vivos, la diversidad de individuos y especies y la transmisión de características hereditarias, sino que además introdujo maneras nuevas de hacer filosofía. La teoría de la selección natural hace superflua cualquier posibilidad de apelar a explicaciones de tipo finalista en la ciencia. Desde Aristóteles se conocen cuatro tipos de causa: la material, la formal, la eficiente y la final. Aunque la causa eficiente es el paradigma de explicación por exce-lencia de las ciencias naturales, la causa final sigue desempeñando un papel explicativo, por cuanto parece estar arraigada en nuestra estructura humana de pensamiento y la tendencia a presentar explicaciones finalistas sigue siendo recalcitrante. Quizá por estar los seres humanos tan familiarizados con la complejidad inherente a los procesos de diseño en las artes y en la técnica y quizá por la circunstancia de que los seres humanos organizamos casi todas nuestras acciones en torno a propósitos, es decir, a la definición de unos fines para los cuales buscamos unos medios, suponemos por vía de analogía que la naturaleza en su complejidad exige la presencia y acción de un diseñador inteligente. Kant en la Crítica de la facultad de juzgar hace una defensa del carácter "irrenunciable al género humano" de este modelo explicativo. Para contro-vertir esta opinión milenaria, me apoyaré, en investigaciones recientes de Richard Dawkins y de otros biólogos contemporáneos para mostrar con la evolución de ojos en la naturaleza que el surgimiento de órganos de alta complejidad puede ser explicado sin problema con la teoría de la selección natural propuesta por Darwin en 1859.Darwin’s theory of natural selection in The Origin of Species not only laid

  14. Final Review of Safety Assessment Issues at Savannah River Site, August 2011

    Energy Technology Data Exchange (ETDEWEB)

    Napier, Bruce A.; Rishel, Jeremy P.; Bixler, Nathan E.

    2011-12-15

    At the request of Savannah River Nuclear Solutions (SRNS) management, a review team composed of experts in atmospheric transport modeling for environmental radiation dose assessment convened at the Savannah River Site (SRS) on August 29-30, 2011. Though the meeting was prompted initially by suspected issues related to the treatment of surface roughness inherent in the SRS meteorological dataset and its treatment in the MELCOR Accident Consequence Code System Version 2 (MACCS2), various topical areas were discussed that are relevant to performing safety assessments at SRS; this final report addresses these topical areas.

  15. Indium arsenide as a material for biological applications: Assessment of surface modifications, toxicity, and biocompatibility

    Science.gov (United States)

    Jewett, Scott A.

    III-V semiconductors such as InAs have recently been employed in a variety of applications where the electronic and optical characteristics of traditional, silicon-based materials are inadequate. InAs has a narrow band gap and very high electron mobility in the near-surface region, which makes it very attractive for high performance transistors, optical applications, and chemical sensing. However, InAs forms an unstable surface oxide layer in ambient conditions, which can corrode over time and leach toxic indium and arsenic components. Current research has gone into making InAs more attractive for biological applications through passivation of the surface by adlayer adsorption. In particular, wet-chemical methods are current routes of exploration due to their simplicity, low cost, and flexibility in the type of passivating molecule. This dissertation focuses on surface modifications of InAs using wet-chemical methods in order to further its use in biological applications. First, the adsorption of collagen binding peptides and mixed peptide/thiol adlayers onto InAs was assessed. X-ray photoelectron spectroscopy (XPS) along with atomic force microscopy (AFM) data suggested that the peptides successfully adsorbed onto InAs, but were only able to block oxide regrowth to a relatively low extent. This low passivation ability is due to the lack of covalent bonds of the peptide to InAs, which are necessary to effectively block oxide regrowth. The addition of a thiol, in the form of mixed peptide/thiol adlayers greatly enhanced passivation of InAs while maintaining peptide presence on the surface. Thiols form tight, covalent bonds with InAs, which prevents oxide regrowth. The presence of the collagen-binding peptide on the surface opens the door to subsequent modification with collagen or polyelectrolyte-based adlayers. Next, the stability and toxicity of modified InAs substrates were determined using inductively coupled plasma mass spectrometry (ICP-MS) and zebrafish

  16. Joint irrigation districts hydropower assessment study. Final feasibility assessment report. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-02-01

    In August 1978, the United States Department of Energy and the Turlock Irrigation District entered into a cooperative agreement for a Joint District's Low-Head Hydropower Assessment Study. The purpose of the agreement was to carry out a study of the hydropower potential at sites within the borders of the Turlock, Merced, South San Joaquin, and Oakdale Irrigation Districts in California. The required data were gathered and analyzed. The results of this study indicate the total potential small hydropower capacity with the Joint Districts is 19,560 kW installed with an annual energy generation of 68,561,800 kWh. This is equivalent to oil-savings of 118,616 barrels per y.

  17. Evaluation of safety assessment methodologies in Rocky Flats Risk Assessment Guide (1985) and Building 707 Final Safety Analysis Report (1987)

    Energy Technology Data Exchange (ETDEWEB)

    Walsh, B.; Fisher, C.; Zigler, G.; Clark, R.A. [Science and Engineering Associates, Inc., Albuquerque, NM (United States)

    1990-11-09

    FSARs. Rockwell International, as operating contractor at the Rocky Flats plant, conducted a safety analysis program during the 1980s. That effort resulted in Final Safety Analysis Reports (FSARs) for several buildings, one of them being the Building 707 Final Safety Analysis Report, June 87 (707FSAR) and a Plant Safety Analysis Report. Rocky Flats Risk Assessment Guide, March 1985 (RFRAG85) documents the methodologies that were used for those FSARs. Resources available for preparation of those Rocky Flats FSARs were very limited. After addressing the more pressing safety issues, some of which are described below, the present contractor (EG&G) intends to conduct a program of upgrading the FSARs. This report presents the results of a review of the methodologies described in RFRAG85 and 707FSAR and contains suggestions that might be incorporated into the methodology for the FSAR upgrade effort.

  18. Who Should Change Biology Education: An Analysis of the Final Report on the Vision and Change in Undergraduate Biology Education Conference

    OpenAIRE

    Kuddus, Ruhul H.

    2013-01-01

    Biological sciences have become the frontiers of new discoveries, major tools of solving local and global problems and creators of new employments. The high rate of new discoveries in biological sciences; new advances in cognitive sciences, learning research, computing and informatics; enhanced fusion of biological sciences and other natural sciences; and the requirement of the learners of the digital generation have presented a multitude of challenges to biology teaching and learning. In mee...

  19. The phaseness of human biological development assesse with the use of selected physicochemical methods

    OpenAIRE

    Czapla, Zbigniew

    2000-01-01

    The principal idea of the work was to show a new, original method of description of the phenomena of human biological development with the use of nonstandard research methods so far unused in the ontogenetic studies in regard to the stable and involutional phases of ontogenesis. The main purpose of the work was to assess with selected methods individual reactions of a human organism in ontogenesis against the development of the population. Two research methods were selec...

  20. Impact assessment of HIV infection on biological variables in Angami Nagas: Gender differences

    OpenAIRE

    Athoni Rhetso; S.L. Malik

    2012-01-01

    In order to assess gender differences for the impact of HIV infection on biological variables in Angami Nagas, a cross sectional analysis was performed comparing 400 control (HIV negative) adult Angamis (200 males and 200 females) and 60 affected (HIV positive) adult Angamis collected from Kohima, Nagaland (India). Both control males and females are significantly heavier, and have greater grip strengths, higher lung functions and marginally higher blood pressure than the respective HIV affect...

  1. Relevance of Crop Biology for Environmental Risk Assessment of Genetically Modified Crops in Africa

    OpenAIRE

    Akinbo, Olalekan; Hancock, James F.; Makinde, Diran

    2015-01-01

    Knowledge about the crop biology of economic crops in Africa is needed for regulators to accurately review dossiers and conduct comprehensive environmental risk assessments (ERAs). This information allows regulators to decide whether biotech crops present a risk to biodiversity, since crossing between domesticated crops and their wild relatives could affect the adaptations of the wild species. The criteria that should be used in the evaluation of African crops for ERA include growth habit, ce...

  2. FINAL REPORT: DOE CONTRACT NUMBER FG0205ER64026 Biological Neutron Scattering: A Collaboration with the Oak Ridge Center for Structural Molecular Biology

    Energy Technology Data Exchange (ETDEWEB)

    Jill Trewhella

    2011-01-12

    The overarching goal of this project was to promote applications of small-angle scattering in structural molecular biology by providing model examples of cutting edge applications that demonstrate the unique capabilities and potential of the DOE national user facilities at Oak Ridge, especially the newly commissioned BioSANS. The approach taken was three-fold: (1) to engage in high impact collaborative research projects that would benefit from small-angle neutron scattering to both demonstrate the power of the technique while expanding the potential user community; (2) to provide access to scattering facilities established at the University of Utah to as broad a set of researchers as possible to increase the expertise in small-angle scattering generally; and (3) to develop new methods and tools for small-angle scattering. To these ends, three major research collaborations were pursued that resulted in a significant body of published work where neutron scattering and contrast variation played a major role. These major collaborations involved studies of protein complexes involved in (1) bacterial transcription regulation and adaptive response (a DOE/BER priority area); (2) regulation of cardiac muscle; and (3) neuronal disorders. In addition, to broaden the impact of the project, smaller collaborative efforts were supported that used either small-angle X-ray or neutron scattering. Finally, the DOE supported facilities at the University of Utah were made available to researchers on a service basis and a number of independent groups took advantage of this opportunity. In all of this work, there was an emphasis on the training of students and post docs in scattering techniques, and a set of publications (a book chapter, a review, and an encyclopedia article) were produced to guide the non-specialist potential user of scattering techniques in successful applications of the techniques. We also developed a suite of user friendly web-based computational tools currently

  3. Increasing URM Undergraduate Student Success through Assessment-Driven Interventions: A Multiyear Study Using Freshman-Level General Biology as a Model System

    Science.gov (United States)

    Carmichael, Mary C.; St. Clair, Candace; Edwards, Andrea M.; Barrett, Peter; McFerrin, Harris; Davenport, Ian; Awad, Mohamed; Kundu, Anup; Ireland, Shubha Kale

    2016-01-01

    Xavier University of Louisiana leads the nation in awarding BS degrees in the biological sciences to African-American students. In this multiyear study with ∼5500 participants, data-driven interventions were adopted to improve student academic performance in a freshman-level general biology course. The three hour-long exams were common and administered concurrently to all students. New exam questions were developed using Bloom’s taxonomy, and exam results were analyzed statistically with validated assessment tools. All but the comprehensive final exam were returned to students for self-evaluation and remediation. Among other approaches, course rigor was monitored by using an identical set of 60 questions on the final exam across 10 semesters. Analysis of the identical sets of 60 final exam questions revealed that overall averages increased from 72.9% (2010) to 83.5% (2015). Regression analysis demonstrated a statistically significant correlation between high-risk students and their averages on the 60 questions. Additional analysis demonstrated statistically significant improvements for at least one letter grade from midterm to final and a 20% increase in the course pass rates over time, also for the high-risk population. These results support the hypothesis that our data-driven interventions and assessment techniques are successful in improving student retention, particularly for our academically at-risk students. PMID:27543637

  4. Assessing isocyanate exposures in polyurethane industry sectors using biological and air monitoring methods.

    Science.gov (United States)

    Creely, K S; Hughson, G W; Cocker, J; Jones, K

    2006-08-01

    Isocyanates, as a chemical group, are considered to be the biggest cause of occupational asthma in the UK. Monitoring of airborne exposures to total isocyanate is costly, requiring considerable expertise, both in terms of sample collection and chemical analysis and cannot be used to assess the effectiveness of protection from wearing respiratory protective equipment (RPE). Biological monitoring by analysis of metabolites in urine can be a relatively simple and inexpensive way to assess exposure to isocyanates. It may also be a useful way to evaluate the effectiveness of control measures in place. In this study biological and inhalation monitoring were undertaken to assess exposure in a variety of workplaces in the non-motor vehicle repair sector. Companies selected to participate in the survey included only those judged to be using good working practices when using isocyanate formulations. This included companies that used isocyanates to produce moulded polyurethane products, insulation material and those involved in industrial painting. Air samples were collected by personal monitoring and were analysed for total isocyanate content. Urine samples were collected soon after exposure and analysed for the metabolites of different isocyanate species, allowing calculation of the total metabolite concentration. Details of the control measures used and observed contamination of exposed skin were also recorded. A total of 21 companies agreed to participate in the study, with exposure measurements being collected from 22 sites. The airborne isocyanate concentrations were generally very low (range 0.0005-0.066 mg m(-3)). A total of 50 of the 70 samples were polyurethane foam insulation (0.023 mg m(-3)). The most commonly detected isocyanate in the urine was hexamethylene diisocyanate, which was detected in 21 instances. The geometric mean total isocyanate metabolite concentration for the dataset was 0.29 micromol mol(-1) creatinine (range 0.05-12.64 micromol mol(-1

  5. Rubric-based tools to support the monitoring and assessment of Bachelor’s Final Projects

    Directory of Open Access Journals (Sweden)

    Verónica MORENO OLIVER

    2015-12-01

    Full Text Available The role of Bachelor’s Final Projects (BFP in Engineering Education is critical since it offers the opportunity for students to integrate and employ specific and transversal competences they have developed along the degree. However, given the special characteristics of this curriculum component (personalized according to the student’s interests, the number of teachers involved, the changing assessment boards, etc., the systematization of its formative and summative assessment has been extensively recognized as problematic but highly necessary. To face this problem, there are several recent initiatives reported in the literature that propose a set of rubrics as tools for project advisors and board members to structure the assessment. In this paper, we report the experience in the Engineering School at Universitat Pompeu Fabra (Barcelona employing a rubricbased approach as part of an assessment guide (with a web-based support tool for BFP. The guide has been evaluated using quantitative and qualitative data gathering techniques used before, during and after the rubrics use, and the results provide insights about its utility, pertinence, user-friendliness, preciseness and actual adoption. Findings led to the provision an additional feature in the web-based tool for the integrated assessment of transversal and specific competences and a view of a summarized version of the rubrics that can be used using mobile devices.

  6. Visual Representations on High School Biology, Chemistry, Earth Science, and Physics Assessments

    Science.gov (United States)

    LaDue, Nicole D.; Libarkin, Julie C.; Thomas, Stephen R.

    2015-12-01

    The pervasive use of visual representations in textbooks, curricula, and assessments underscores their importance in K-12 science education. For example, visual representations figure prominently in the recent publication of the Next Generation Science Standards (NGSS Lead States in Next generation science standards: for states, by states. Achieve, Inc. on behalf of the twenty-six states and partners that collaborated on the NGSS, 2013). Although assessments of the NGSS have yet to be developed, most students are currently evaluated on their ability to interpret science visuals. While numerous studies exist on particular visuals, it is unclear whether the same types of visuals are emphasized in all science disciplines. The present study is an evaluation of the similarities and differences of visuals used to assess students' knowledge of chemistry, earth science, living environment (biology), and physics on the New York State Regents examination. Analysis of 266 distinct visual representations categorized across the four content examinations reveals that the frequency and type of visuals vary greatly between disciplines. Diagrams, Graphs, Tables, and Maps are the most prevalent across all science disciplines. Maps, Cartograms, and Time Charts are unique to the Earth Science examination, and Network Diagrams are unique to the living environment (biology) examination. This study identifies which representations are most critical for training students across the science disciplines in anticipation of the implementation and eventual assessment of the NGSS.

  7. Macroinvertebrate-based assessment of biological condition at selected sites in the Eagle River watershed, Colorado, 2000-07

    Science.gov (United States)

    Zuellig, Robert E.; Bruce, James F.; Healy, Brian D.; Williams, Cory A.

    2010-01-01

    The U.S. Geological Survey (USGS), in cooperation with the Colorado River Water Conservation District, Eagle County, Eagle River Water and Sanitation District, Upper Eagle Regional Water Authority, Colorado Department of Transportation, City of Aurora, Town of Eagle, Town of Gypsum, Town of Minturn, Town of Vail, Vail Resorts, Colorado Springs Utilities, Denver Water, and the U.S. Department of Agriculture Forest Service (FS), compiled macroinvertebrate (73 sites, 124 samples) data previously collected in the Eagle River watershed from selected USGS and FS studies, 2000-07. These data were analyzed to assess the biological condition (that is, biologically ?degraded? or ?good?) at selected sites in the Eagle River watershed and determine if site class (for example, urban or undeveloped) described biological condition. An independently developed predictive model was applied to calculate a site-specific measure of taxonomic completeness for macroinvertebrate communities, where taxonomic completeness was expressed as the ratio of observed (O) taxa to those expected (E) to occur at each site. Macroinvertebrate communities were considered degraded at sites were O/E values were less than 0.80, indicating that at least 20 percent of expected taxa were not observed. Sites were classified into one of four classes (undeveloped, adjacent road or highway or both, mixed, urban) using a combination of riparian land-cover characteristics, examination of topographic maps and aerial imagery, screening for exceedances in water-quality standards, and best professional judgment. Analysis of variance was used to determine if site class accounted for variability in mean macroinvertebrate O/E values. Finally, macroinvertebrate taxa observed more or less frequently than expected at urban sites were indentified. This study represents the first standardized assessment of biological condition of selected sites distributed across the Eagle River watershed. Of the 73 sites evaluated, just over

  8. Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks

    Directory of Open Access Journals (Sweden)

    Martin Florian

    2012-05-01

    Full Text Available Abstract Background High-throughput measurement technologies produce data sets that have the potential to elucidate the biological impact of disease, drug treatment, and environmental agents on humans. The scientific community faces an ongoing challenge in the analysis of these rich data sources to more accurately characterize biological processes that have been perturbed at the mechanistic level. Here, a new approach is built on previous methodologies in which high-throughput data was interpreted using prior biological knowledge of cause and effect relationships. These relationships are structured into network models that describe specific biological processes, such as inflammatory signaling or cell cycle progression. This enables quantitative assessment of network perturbation in response to a given stimulus. Results Four complementary methods were devised to quantify treatment-induced activity changes in processes described by network models. In addition, companion statistics were developed to qualify significance and specificity of the results. This approach is called Network Perturbation Amplitude (NPA scoring because the amplitudes of treatment-induced perturbations are computed for biological network models. The NPA methods were tested on two transcriptomic data sets: normal human bronchial epithelial (NHBE cells treated with the pro-inflammatory signaling mediator TNFα, and HCT116 colon cancer cells treated with the CDK cell cycle inhibitor R547. Each data set was scored against network models representing different aspects of inflammatory signaling and cell cycle progression, and these scores were compared with independent measures of pathway activity in NHBE cells to verify the approach. The NPA scoring method successfully quantified the amplitude of TNFα-induced perturbation for each network model when compared against NF-κB nuclear localization and cell number. In addition, the degree and specificity to which CDK

  9. Understanding the Reading Attributes and Their Cognitive Relationships on a High-Stakes Biology Assessment

    Science.gov (United States)

    Rawlusyk, Kevin James

    Test items used to assess learners' knowledge on high-stakes science examinations contain contextualized questions that unintentionally assess reading skill along with conceptual knowledge. Therefore, students who are not proficient readers are unable to comprehend the text within the test item to demonstrate effectively their level of science knowledge. The purpose of this quantitative study was to understand what reading attributes were required to successfully answer the Biology 30 Diploma Exam. Furthermore, the research sought to understand the cognitive relationships among the reading attributes through quantitative analysis structured by the Attribute Hierarchy Model (AHM). The research consisted of two phases: (1) Cognitive development, where the cognitive attributes of the Biology 30 Exam were specified and hierarchy structures were developed; and (2) Psychometric analysis, that statistically tested the attribute hierarchy using the Hierarchy Consistency Index (HCI), and calculate attribute probabilities. Phase one of the research used January 2011, Biology 30 Diploma Exam, while phase two accessed archival data for the 9985 examinees who took the assessment on January 24th, 2011. Phase one identified ten specific reading attributes, of which five were identified as unique subsets of vocabulary, two were identified as reading visual representations, and three corresponded to general reading skills. Four hierarchical cognitive model were proposed then analyzed using the HCI as a mechanism to explain the relationship among the attributes. Model A had the highest HCI value (0.337), indicating an overall poor data fit, yet for the top achieving examinees the model had an excellent model fit with an HCI value of 0.888, and for examinees that scored over 60% there was a moderate model fit (HCI = 0.592). Linear regressions of the attribute probability estimates suggest that there is a cognitive relationship among six of the ten reading attributes (R2 = 0.958 and 0

  10. Bibliographical database of radiation biological dosimetry and risk assessment: Part 1, through June 1988

    Energy Technology Data Exchange (ETDEWEB)

    Straume, T.; Ricker, Y.; Thut, M.

    1988-08-29

    This database was constructed to support research in radiation biological dosimetry and risk assessment. Relevant publications were identified through detailed searches of national and international electronic databases and through our personal knowledge of the subject. Publications were numbered and key worded, and referenced in an electronic data-retrieval system that permits quick access through computerized searches on publication number, authors, key words, title, year, and journal name. Photocopies of all publications contained in the database are maintained in a file that is numerically arranged by citation number. This report of the database is provided as a useful reference and overview. It should be emphasized that the database will grow as new citations are added to it. With that in mind, we arranged this report in order of ascending citation number so that follow-up reports will simply extend this document. The database cite 1212 publications. Publications are from 119 different scientific journals, 27 of these journals are cited at least 5 times. It also contains reference to 42 books and published symposia, and 129 reports. Information relevant to radiation biological dosimetry and risk assessment is widely distributed among the scientific literature, although a few journals clearly dominate. The four journals publishing the largest number of relevant papers are Health Physics, Mutation Research, Radiation Research, and International Journal of Radiation Biology. Publications in Health Physics make up almost 10% of the current database.

  11. Bibliographical database of radiation biological dosimetry and risk assessment: Part 1, through June 1988

    International Nuclear Information System (INIS)

    This database was constructed to support research in radiation biological dosimetry and risk assessment. Relevant publications were identified through detailed searches of national and international electronic databases and through our personal knowledge of the subject. Publications were numbered and key worded, and referenced in an electronic data-retrieval system that permits quick access through computerized searches on publication number, authors, key words, title, year, and journal name. Photocopies of all publications contained in the database are maintained in a file that is numerically arranged by citation number. This report of the database is provided as a useful reference and overview. It should be emphasized that the database will grow as new citations are added to it. With that in mind, we arranged this report in order of ascending citation number so that follow-up reports will simply extend this document. The database cite 1212 publications. Publications are from 119 different scientific journals, 27 of these journals are cited at least 5 times. It also contains reference to 42 books and published symposia, and 129 reports. Information relevant to radiation biological dosimetry and risk assessment is widely distributed among the scientific literature, although a few journals clearly dominate. The four journals publishing the largest number of relevant papers are Health Physics, Mutation Research, Radiation Research, and International Journal of Radiation Biology. Publications in Health Physics make up almost 10% of the current database

  12. Historical precedence and technical requirements of biological weapons use : a threat assessment.

    Energy Technology Data Exchange (ETDEWEB)

    Estes, Daniel P.; Vogel, Kathleen Margaret; Gaudioso, Jennifer Marie; Hickok, Lauren T.; Jung, Danielle F.; Barnett, Natalie Beth; Frerichs, Rebecca L.; Salerno, Reynolds Mathewson

    2004-05-01

    The threat from biological weapons is assessed through both a comparative historical analysis of the patterns of biological weapons use and an assessment of the technological hurdles to proliferation and use that must be overcome. The history of biological weapons is studied to learn how agents have been acquired and what types of states and substate actors have used agents. Substate actors have generally been more willing than states to use pathogens and toxins and they have focused on those agents that are more readily available. There has been an increasing trend of bioterrorism incidents over the past century, but states and substate actors have struggled with one or more of the necessary technological steps. These steps include acquisition of a suitable agent, production of an appropriate quantity and form, and effective deployment. The technological hurdles associated with the steps present a real barrier to producing a high consequence event. However, the ever increasing technological sophistication of society continually lowers the barriers, resulting in a low but increasing probability of a high consequence bioterrorism event.

  13. Assessment of nitrogen and sulphur cycle bacteria and shrimp production in ponds treated with biological products

    Institute of Scientific and Technical Information of China (English)

    Thangapalam Jawahar Abraham; Shubhadeep Ghosh; Debasis Sasmal

    2015-01-01

    Objective:To study the influence of biological products on the levels of nitrogen and sulphur cycle bacteria in shrimp culture systems of West Bengal, India. Methods: The pond water and sediment samples were analyzed for physico-chemical parameters as per standard methods. The bacteria involved in ammonification, nitrification, denitrification, sulphate reduction and sulphur oxidation were enumerated by most probable number technique. Results:The semi-intensive and modified extensive shrimp farms used a variety of biological products during various stages of production. No biological products were used in traditional farms. The water and sediment samples of modified extensive system recorded significantly higher mean heterotrophic bacterial counts. The counts of ammonia, nitrite and sulphur oxidizers, and nitrate and sulphate reducers varied among the systems. The cycling of nitrogen and sulphur appeared to be affected with the intensification of culture practices. Conclusions:The application of biological products in certain systems helped to maintain the bacteria involved in nitrogen and sulphur cycles and safe levels of ammonia, nitrite and nitrate. An assessment of these metabolically active bacteria in shrimp culture ponds and the application of right kind microbial products would help ameliorate the organic pollution in shrimp aquaculture.

  14. Development and Assessment of Modules to Integrate Quantitative Skills in Introductory Biology Courses.

    Science.gov (United States)

    Hoffman, Kathleen; Leupen, Sarah; Dowell, Kathy; Kephart, Kerrie; Leips, Jeff

    2016-01-01

    Redesigning undergraduate biology courses to integrate quantitative reasoning and skill development is critical to prepare students for careers in modern medicine and scientific research. In this paper, we report on the development, implementation, and assessment of stand-alone modules that integrate quantitative reasoning into introductory biology courses. Modules are designed to improve skills in quantitative numeracy, interpreting data sets using visual tools, and making inferences about biological phenomena using mathematical/statistical models. We also examine demographic/background data that predict student improvement in these skills through exposure to these modules. We carried out pre/postassessment tests across four semesters and used student interviews in one semester to examine how students at different levels approached quantitative problems. We found that students improved in all skills in most semesters, although there was variation in the degree of improvement among skills from semester to semester. One demographic variable, transfer status, stood out as a major predictor of the degree to which students improved (transfer students achieved much lower gains every semester, despite the fact that pretest scores in each focus area were similar between transfer and nontransfer students). We propose that increased exposure to quantitative skill development in biology courses is effective at building competency in quantitative reasoning. PMID:27146161

  15. Development and Assessment of Modules to Integrate Quantitative Skills in Introductory Biology Courses.

    Science.gov (United States)

    Hoffman, Kathleen; Leupen, Sarah; Dowell, Kathy; Kephart, Kerrie; Leips, Jeff

    2016-01-01

    Redesigning undergraduate biology courses to integrate quantitative reasoning and skill development is critical to prepare students for careers in modern medicine and scientific research. In this paper, we report on the development, implementation, and assessment of stand-alone modules that integrate quantitative reasoning into introductory biology courses. Modules are designed to improve skills in quantitative numeracy, interpreting data sets using visual tools, and making inferences about biological phenomena using mathematical/statistical models. We also examine demographic/background data that predict student improvement in these skills through exposure to these modules. We carried out pre/postassessment tests across four semesters and used student interviews in one semester to examine how students at different levels approached quantitative problems. We found that students improved in all skills in most semesters, although there was variation in the degree of improvement among skills from semester to semester. One demographic variable, transfer status, stood out as a major predictor of the degree to which students improved (transfer students achieved much lower gains every semester, despite the fact that pretest scores in each focus area were similar between transfer and nontransfer students). We propose that increased exposure to quantitative skill development in biology courses is effective at building competency in quantitative reasoning.

  16. Life Cycle Assessments Applied to First Generation Biofuels Used in France. Final report

    International Nuclear Information System (INIS)

    Climatic concerns become more substantial each day. Proofs of climatic change of man-made origin accumulate. Even if the consequences of such change remain difficult to foresee for most, this major environmental problem is now the subject of great attention by governments and public opinion. In this context, biofuels have known a growing interest over the last years. This enthusiasm is essentially based on their potential to reduce non-renewable energy consumption, notably petroleum, and to reduce greenhouse gas emissions (GHG) for the transportation sector. Indeed, the transportation sector currently generates about 14% of the world's GHG at a growth rate of about 2% per year that is particularly difficult to reduce. The issue of biofuel balances on these two criteria (GHG emission and non-renewable energy consumption) is therefore fundamental because it justifies largely the different forms of public financial support devoted to ensure the development of these pathways. Thus, numerous studies are aimed at comparing biofuels to equivalent petroleum fuels (gasoline and diesel) in order to assess GHG emission reduction potential associated with using biofuels in transportation. The Directive 2009/28/CE of April 29, 2009 dedicated to Renewable Energies promotion (RE Directive) sets forth a compelling objective, asking each Member State to make sure that the portion of energy produced from renewable sources in all forms of transportation will be at least equal to 10% of its final energy consumption in the transportation sector by 2020. This objective is set subject to a production of sustainable nature and to second generation biofuel availability on the market. The RE Directive introduces several criteria for qualifying biofuels' sustainability. Thus, biofuels should not be produced from land recognized as of great value in terms of biological diversity: forest undisturbed by important human activity, zone assigned to nature conservation, meadows presenting a great

  17. Review and critique of California electricity generation methods assessment project. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Knecht, R.L.

    1977-05-01

    The author offers a critique of the TRW Energy Systems Management Division's final report on its California electricity generation methods assessment project (EAPA 03:3812). Briefly, the TRW report provided information on current and forecasted economic costs of different methods of electricity generation needed to meet base-, intermediate-, and peak-load demand requirements in California. Additionally, the reliability, fuel requirements, other resource requirements, and environmental impacts of the different methods of generating electricity were assessed. The author reviews the subjects as they appear in the TRW report. In an appendix, Mr. Knecht presents a detailed computation of his comparison of the costs of coal-fired and nuclear electric generation. (MCW)

  18. Final Report to the Department of the Energy for Project Entitled Rare Isotope Science Assessment Committee

    International Nuclear Information System (INIS)

    The Rare Isotope Science Assessment Committee (RISAC) was convened by the National Research Council in response to an informal request from the DOE's Office of Nuclear Physics and the White House Office of Management and Budget. The charge to the committee is to examine and assess the broader scientific and international contexts of a U.S.-based rare-isotope facility. The committee met for the first time on December 16-17, 2005, in Washington, DC, and held three subsequent meetings. The committee's's final report was publicly released in unedited, prepublication form on Friday, December 8, 2006. The report was published in full-color by the National Academies Press in April 2007. Copies of the report were distributed to key decision makers and stakeholders around the world.

  19. Final report on the Project Research 'Assessment of Human Exposure to Environmental Radiation'

    International Nuclear Information System (INIS)

    This is the final report of the Project Research, 'Assessment of Human Exposure to Environmental Radiation', which has been conducted during the period 1983-1988. With the objective of assessing risk of environmental radioactivity to the population, the Project was divided into the following five research groups: (1) research for establishing calculation models and parameters in transfer of radionuclides from crop species through the human body; (2) research for analyzing transfer of radionuclides in the ocean and their contributions to exposure doses in the human body; (3) research for surveying accuracy of exposure models for the external body and respiratory organ and the influential factors; (4) research for determining uptake and biokinetics of radionuclides in the body; and (5) research for estimating and evaluating physical and physiological characteristics of reference Japanese man and the populaltion doses. Effluents from nuclear power plants and reprocessing plants were regarded as radionuclide sources in the water and atmosphere. (N.K.)

  20. Assessing Student Understanding of the "New Biology": Development and Evaluation of a Criterion-Referenced Genomics and Bioinformatics Assessment

    Science.gov (United States)

    Campbell, Chad Edward

    Over the past decade, hundreds of studies have introduced genomics and bioinformatics (GB) curricula and laboratory activities at the undergraduate level. While these publications have facilitated the teaching and learning of cutting-edge content, there has yet to be an evaluation of these assessment tools to determine if they are meeting the quality control benchmarks set forth by the educational research community. An analysis of these assessment tools indicated that learning. To remedy this situation the development of a robust GB assessment aligned with the quality control benchmarks was undertaken in order to ensure evidence-based evaluation of student learning outcomes. Content validity is a central piece of construct validity, and it must be used to guide instrument and item development. This study reports on: (1) the correspondence of content validity evidence gathered from independent sources; (2) the process of item development using this evidence; (3) the results from a pilot administration of the assessment; (4) the subsequent modification of the assessment based on the pilot administration results and; (5) the results from the second administration of the assessment. Twenty-nine different subtopics within GB (Appendix B: Genomics and Bioinformatics Expert Survey) were developed based on preliminary GB textbook analyses. These subtopics were analyzed using two methods designed to gather content validity evidence: (1) a survey of GB experts (n=61) and (2) a detailed content analyses of GB textbooks (n=6). By including only the subtopics that were shown to have robust support across these sources, 22 GB subtopics were established for inclusion in the assessment. An expert panel subsequently developed, evaluated, and revised two multiple-choice items to align with each of the 22 subtopics, producing a final item pool of 44 items. These items were piloted with student samples of varying content exposure levels. Both Classical Test Theory (CTT) and Item

  1. Biological Inquiry: A New Course and Assessment Plan in Response to the Call to Transform Undergraduate Biology

    Science.gov (United States)

    Goldey, Ellen S.; Abercrombie, Clarence L.; Ivy, Tracie M.; Kusher, Dave I.; Moeller, John F.; Rayner, Doug A.; Smith, Charles F.; Spivey, Natalie W.

    2012-01-01

    We transformed our first-year curriculum in biology with a new course, Biological Inquiry, in which greater than 50% of all incoming, first-year students enroll. The course replaced a traditional, content-driven course that relied on outdated approaches to teaching and learning. We diversified pedagogical practices by adopting guided inquiry in…

  2. Advanced turbine systems sensors and controls needs assessment study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, R.L.; Fry, D.N.; McEvers, J.A.

    1997-02-01

    The Instrumentation and Controls Division of the Oak Ridge National Laboratory performed an assessment of the sensors and controls needs for land-based advanced gas turbines being designed as a part of the Department of Energy`s (DOE`s) Advanced Turbine Systems (ATS) Program for both utility and industrial applications. The assessment included visits to five turbine manufacturers. During these visits, in-depth discussions were held with design and manufacturing staff to obtain their views regarding the need for new sensors and controls for their advanced turbine designs. The Unsteady Combustion Facilities at the Morgantown Energy Technology Center was visited to assess the need for new sensors for gas turbine combustion research. Finally, a workshop was conducted at the South Carolina Energy Research and Development Center which provided a forum for industry, laboratory, and university engineers to discuss and prioritize sensor and control needs. The assessment identified more than 50 different measurement, control, and monitoring needs for advanced turbines that cannot currently be met from commercial sources. While all the identified needs are important, some are absolutely critical to the success of the ATS Program.

  3. The impact of biology on risk assessment -- Workshop of the National Research Council's board on radiation effects research. Meeting report

    International Nuclear Information System (INIS)

    The linear, nonthreshold extrapolation from a dose-response relationship for ionizing radiation derived at higher doses to doses for which regulatory standards are proposed is being challenged by some scientists and defended by others. It appears that the risks associated with exposures to doses of interest are below the risks that can be measured with epidemiologic studies. Therefore, many have looked to biology to provide information relevant to risk assessment. The workshop reported here, ''The Impact of biology on Risk Assessment,'' was planned to address the need for further information by bringing together scientists who have been working in key fields of biology and others who have been contemplating the issues associated specifically with this question. The goals of the workshop were to summarize and review the status of the relevant biology, to determine how the reported biologic data might influence risk assessment, and to identify subjects on which more data is needed

  4. Benefits of a Biological Monitoring Program for Assessing Remediation Performance and Long-Term Stewardship - 12272

    International Nuclear Information System (INIS)

    The Biological Monitoring and Abatement Program (BMAP) is a long-running program that was designed to evaluate biological conditions and trends in waters downstream of Department of Energy (DOE) facilities in Oak Ridge, Tennessee. BMAP monitoring has focused on aquatic pathways from sources to biota, which is consistent with the sites' clean water regulatory focus and the overall cleanup strategy which divided remediation areas into watershed administrative units. Specific programmatic goals include evaluating operational and legacy impacts to nearby streams and the effectiveness of implemented remediation strategies at the sites. The program is characterized by consistent, long-term sampling and analysis methods in a multidisciplinary and quantitative framework. Quantitative sampling has shown conclusively that at most Oak Ridge stream sites, fish and aquatic macro-invertebrate communities have improved considerably since the 1980s. Monitoring of mercury and PCBs in fish has shown that remedial and abatement actions have also improved stream conditions, although in some cases biological monitoring suggests further actions are needed. Follow-up investigations have been implemented by BMAP to identify sources or causes, consistent with an adaptive management approach. Biological monitoring results to date have not only been used to assess regulatory compliance, but have provided additional benefits in helping address other components of the DOE's mission, including facility operations, natural resource, and scientific goals. As a result the program has become a key measure of long-term trends in environmental conditions and of high value to the Oak Ridge environmental management community, regulators, and the public. Some of the BMAP lessons learned may be of value in the design, implementation, and application of other long-term monitoring and stewardship programs, and assist environmental managers in the assessment and prediction of the effectiveness of remedial

  5. Advanced computational methods for the assessment of reactor core behaviour during reactivity initiated accidents. Final report

    International Nuclear Information System (INIS)

    The document at hand serves as the final report for the reactor safety research project RS1183 ''Advanced Computational Methods for the Assessment of Reactor Core Behavior During Reactivity-Initiated Accidents''. The work performed in the framework of this project was dedicated to the development, validation and application of advanced computational methods for the simulation of transients and accidents of nuclear installations. These simulation tools describe in particular the behavior of the reactor core (with respect to neutronics, thermal-hydraulics and thermal mechanics) at a very high level of detail. The overall goal of this project was the deployment of a modern nuclear computational chain which provides, besides advanced 3D tools for coupled neutronics/ thermal-hydraulics full core calculations, also appropriate tools for the generation of multi-group cross sections and Monte Carlo models for the verification of the individual calculational steps. This computational chain shall primarily be deployed for light water reactors (LWR), but should beyond that also be applicable for innovative reactor concepts. Thus, validation on computational benchmarks and critical experiments was of paramount importance. Finally, appropriate methods for uncertainty and sensitivity analysis were to be integrated into the computational framework, in order to assess and quantify the uncertainties due to insufficient knowledge of data, as well as due to methodological aspects.

  6. Final report of the project performance assessment and economic evaluation of nuclear waste management

    International Nuclear Information System (INIS)

    The publication is the final report of project Performance Assessment and Economic Evaluation of Nuclear Waste Management (TOKA) at the Nuclear Engineering Laboratory of VTT (Technical Research Centre of Finland), forming part of the Publicly Financed Nuclear Waste Management Research Programme (JYT). The project covers safety and cost aspects of all phases of nuclear waste management. The main emphasis has been on developing an integrated system of models for performance assessment of nuclear waste repositories. During the four years the project has so far been in progress, the total amount of work has been around 14 person-years. Computer codes are the main tools in the project, they are either developed by the project team or acquired from abroad. In-house model development has been especially active in groundwater flow, near-field and migration modelling. The quantitative interpretation of Finnish tracer experiments in the laboratory and natural analogue studies at Palmottu support performance assessments via increased confidence in the migration concepts used. The performance assessment philosophy adopted by the team consists of deterministic modelling and pragmatic scenario analysis. This is supported by the long-term experience in practical performance assessment of the team, and in theoretical probabilistic modelling exercises. The radiological risks of spent fuel transportation from the Loviisa nuclear power plant to Russia have been analysed using a probabilistic computer code and Finnish traffic accident statistics. The project assists the authorities in the annual assessment of utility estimates of funding needs for future nuclear waste management operations. The models and methods used within the project are tested in international verification/validation projects

  7. DOE Final Technical Report (2009-2016): "Research Projects for Interrogations of Biological Systems: Training for the Development of Novel Radiotracers"

    Energy Technology Data Exchange (ETDEWEB)

    Jurisson, Silvia [University of Missouri-Columbia; Lever, Susan [University of Missouri-Columbia; Robertson, J. David [University of Missouri-Columbia

    2016-10-04

    This is the final technical report for DOE grant DE-SC-0002040, which was entitled "Research Projects for Interrogations of Biological Systems: Training for the Development of Novel Radiotracers". Included are the students and postdoctoral fellows trained, the publications, dissertations, presentations, and other deliverables for this project.

  8. Assessment of Trichogramma species (Hymenoptera: Trichogrammatidae for biological control in cassava (Manihot esculenta Crantz

    Directory of Open Access Journals (Sweden)

    Marcus Alvarenga Soares

    2014-08-01

    Full Text Available Cassava is the sixth most important crop in the world, and it is attacked by many pests, such as Erinnyis ello (L. (Lepidoptera: Sphingidae. This lepidopteran pest has natural enemies that can efficiently control its population, such as Trichogramma spp. (Hymenoptera: Trichogrammatidae. The objective of this research was to assess the flight capacity, parasitism and emergence of Trichogramma pretiosum, T. marandobai and T. demoraesi and to select the most efficient species among them for biological control programs. The flight capacity of these species was assessed in test units consisting of a plastic PVC cylinder with a rigid, transparent plastic circle on the upper portion of the cylinder and an extruded polystyrene disk to close the bottom of the cylinder. A tube was placed in each test unit containing a card with 300 Anagasta kuehniella (Zeller (Lepidoptera: Pyralidae eggs that had been parasitised by Trichogramma. These cards were later assessed to determine the parasitism rate and adult emergence of these natural enemies. Trichogramma pretiosum presented the highest flight capacity (68 ± 5%, parasitism (74 ± 2% and percentage of adults emerged (91 ± 3% in the laboratory, making this species suitable for mass rearing and release in biological control programs.

  9. Final environmental assessment : Using livestock grazing as a management tool to provide quality wildlife habitat : Silver Dollar Habitat Unit

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This final environmental assessment is for the use of livestock grazing to improve the quality of wildlife habitats within the Silver Dollar Habitat Unit on Charles...

  10. In situ combined chemical and biological assessment of estrogenic pollution in a water recycling system.

    Science.gov (United States)

    Chi, Yulang; Huang, Qiansheng; Zhang, Huanteng; Chen, Yajie; Dong, Sijun

    2016-05-01

    Estrogenic pollution and its control in aquatic systems have drawn substantial attention around the world. The chemical and biological assessment approaches currently utilized in the laboratory or field cannot give an integrated assessment of the pollution when used separately. In this study, in situ chemical and biological methods were combined to detect pollution in a water recycling system. Data for the water quality index (WQI) demonstrated that the water treatment resulted in the decline of pollution from upstream to downstream. Wild male Nile tilapia, Oreochromis niloticus, was sampled in June and September. The concentrations of four common endocrine disrupting chemicals (EDCs) were determined in the tilapia liver by chromatographic analysis methods. The level of 17β-estradiol (E2) declined from upstream to downstream in both months. In contrast, the levels of bisphenol A (BPA), di-(2-ethylhcxyl) phthalate (DEHP), and perfluorooctane sulfonate (PFOS) did not display this declining tendency. The highest relative expression of vitellogenin 1 (VTG1) was observed in tilapia from upstream, then the level significantly decreased along the water system. The relative expression levels of CYP1A1 in the water system were also significantly higher than that of the control. However, no declining trend could be observed along the water system. The change of VTG1 expression corresponded well with that of E2 levels in the tilapia liver. Overall, our study assessed the pollution by endocrine disruptors using chemical and biological data with good correspondence. This study also demonstrated the effectiveness of the water recycling system in eliminating estrogen pollution in municipal sewage. PMID:27155427

  11. 76 FR 13597 - Availability of an Environmental Assessment and Finding of No Significant Impact for a Biological...

    Science.gov (United States)

    2011-03-14

    ...; ] DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service Availability of an Environmental Assessment and Finding of No Significant Impact for a Biological Control Agent for Hawkweeds AGENCY: Animal... subterminalis, into the continental United States as a biological control agent to reduce the severity...

  12. Exposure factors for marine eutrophication impacts assessment based on a mechanistic biological model

    DEFF Research Database (Denmark)

    Cosme, Nuno Miguel Dias; Koski, Marja; Hauschild, Michael Zwicky

    2015-01-01

    ). This pathway is typical of marine eutrophication. A model is proposed to mechanistically estimate the response of coastal marine ecosystems to N inputs. It addresses the biological processes of nutrient-limited primary production (PP), metazoan consumption, and bacterial degradation, in four distinct sinking...... is essential to estimate a marine eutrophication impacts indicator in Life Cycle Impact Assessment (LCIA) of anthropogenic-N emissions. Every relevant process was modelled and the uncertainty of the driving parameters considered low suggesting valid applicability in characterisation modelling in LCIA....

  13. Chemical and biological toxicity assessment of simulated Hanford site low-level waste grouts

    International Nuclear Information System (INIS)

    Defining the potential damage to the biosphere associated with exposure to low-level waste grouting operations at the Hanford Site near Richland, Washington, is difficult and controversial. Combined chemical and biological assessment of grout toxicity is needed to provide information on the potential risks of animal and plant exposure to the grouts. This paper will identify and predict the chemical components of the grout that will have the greatest potential of causing deleterious effects on fish and wildlife indigenous to the Hanford Site. This paper will also determine whether the current grout technology is adequate in controlling toxicant and pollutant releases for regulatory compliance

  14. Imaging the risks - risking the image: Social impact assessment of the final disposal facility

    Energy Technology Data Exchange (ETDEWEB)

    Avolahti, J.; Vira, J. [Posiva Oy, Helsinki (Finland)

    1999-12-01

    Preparations for the final disposal of spent nuclear fuel in Finland started about twenty years ago. At present the work is carried out by Posiva Oy, which in 1996 took over the programme managed earlier by Teollisuuden Voima Oy, one of the country's nuclear power companies. From 1996 on the preparations have been made for all the spent fuel from Finnish nuclear power stations. The site for the final disposal facility will be selected among four alternatives by the end of 2000 and - assuming that the technical approach proposed by Posiva is accepted by the Government and the Parliament - the construction of the repository will start in the 2010s. The disposal operations are planned to be started in 2020. The alternative four sites have gone through a systematic site selection process based on geologic siting criteria and on environmental and cultural considerations. One of the objectives of the process was to avoid inhabited areas, agricultural fields, valuable groundwater or preservation areas as well as areas which might draw interest as regards the potential for ore deposits. The idea was that the field investigations and later the possible disposal facility should not cause any harm to local people. Two of the candidate sites are at present nuclear power plant sites situated at the coast, the two other candidates are inland sites with no nuclear activities. The geologic siting investigations were started in 1987. Interim assessments of the results so far have been made in 1992 and 1996 and a final report of all the investigations will be published before the end of 2000. The present view is that all four candidates are geologically suitable for siting the repository. Posiva's EIA for the final disposal of spent fuel in Finland is nearing completion. A considerable effort was made to involve local groups and individuals in the assessment process. Yet the participation remained limited and consisted mainly of active opponents of the project and of those

  15. The Development and Implementation of an Instrument to Assess Students’ Data Analysis Skills in Molecular Biology

    Directory of Open Access Journals (Sweden)

    Brian J. Rybarczyk

    2014-03-01

    Full Text Available Developing visual literacy skills is an important component of scientific literacy in undergraduate science education.  Comprehension, analysis, and interpretation are parts of visual literacy that describe related data analysis skills important for learning in the biological sciences. The Molecular Biology Data Analysis Test (MBDAT was developed to measure students’ data analysis skills connected with scientific reasoning when analyzing and interpreting scientific data generated from experimental research.  The skills analyzed included basic skills such as identification of patterns and trends in data and connecting a method that generated the data and advanced skills such as distinguishing positive and negative controls, synthesizing conclusions, determining if data supports a hypothesis, and predicting alternative or next-step experiments.  Construct and content validity were established and calculated statistical parameters demonstrate that the MBDAT is valid and reliable for measuring students’ data analysis skills in molecular and cell biology contexts.  The instrument also measures students’ perceived confidence in their data interpretation abilities.  As scientific research continues to evolve in complexity, interpretation of scientific information in visual formats will continue to be an important component of scientific literacy.  Thus science education will need to support and assess students’ development of these skills as part of students’ scientific training.

  16. Analysis and assessment of the detriment in interventional radiology using biological dosimetry methods

    Energy Technology Data Exchange (ETDEWEB)

    Montoro, A.; Almonacid, M.; Villaescusa, J.I. [Hospital Univ. la Fe de Valen cian, Servicio de Proteccion Radiologica, Valencia (Spain); Barquinero, J.F.; Rodriguez, P. [Universitat Autonom a de Barcelona, Servicio de Dosimetria Biologica, Unidad de Antropologia, Departamento de Biologia Animal, Vegetal y Ecologia., Barcelona (Spain); Barrios, L. [Universidad Autonoma de Barcelona, Dept. de Biologia Celular y Fisiologia. Unidad de Biologia Celular, Barcelona (Spain); Verdu, G.; Ramos, M. [Universidad Politecnica de Valencia, Dept. de Ingenieria Quimica y Nuclear, Valencia, (Spain)

    2006-07-01

    Interventional radiologist and staff members usually are exposed to high levels of scattered radiation. As a result, the exposition to radiation procedures can produce detrimental effects that we would have to know. Effective dose is the quantity that better estimates the radiation risk. For this study we have realized an estimation of the radiological detriment to exposed workers of the Hospital la Fe de Valencia. For it, have been used physical doses registered in detectors T.L.D., and doses estimated by biological dosimetry in lymphocytes of peripheral blood. There has been estimated for every case the probability of effect of skin cancer and of non-solid cancers (leukaemia, lymphoma and myeloma), being compared with the baseline probability of natural effect. Biological doses were obtained by extrapolating the yield of dicentrics and translocations to their respective dose -effect curves. The discrepancies observed between physically recorded doses and biological estimated doses indicate that workers did not always wear their dosimeters or the dosimeters were not always in the radiation field. Cytogenetic studies should be extended to more workers to assess the risk derived from their occupational exposure. (authors)

  17. Indoor Air Nuclear, Biological, and Chemical Health Modeling and Assessment System

    Energy Technology Data Exchange (ETDEWEB)

    Stenner, Robert D.; Hadley, Donald L.; Armstrong, Peter R.; Buck, John W.; Hoopes, Bonnie L.; Janus, Michael C.

    2001-03-01

    Indoor air quality effects on human health are of increasing concern to public health agencies and building owners. The prevention and treatment of 'sick building' syndrome and the spread of air-borne diseases in hospitals, for example, are well known priorities. However, increasing attention is being directed to the vulnerability of our public buildings/places, public security and national defense facilities to terrorist attack or the accidental release of air-borne biological pathogens, harmful chemicals, or radioactive contaminants. The Indoor Air Nuclear, Biological, and Chemical Health Modeling and Assessment System (IA-NBC-HMAS) was developed to serve as a health impact analysis tool for use in addressing these concerns. The overall goal was to develop a user-friendly fully functional prototype Health Modeling and Assessment system, which will operate under the PNNL FRAMES system for ease of use and to maximize its integration with other modeling and assessment capabilities accessible within the FRAMES system (e.g., ambient air fate and transport models, water borne fate and transport models, Physiologically Based Pharmacokinetic models, etc.). The prototype IA-NBC-HMAS is designed to serve as a functional Health Modeling and Assessment system that can be easily tailored to meet specific building analysis needs of a customer. The prototype system was developed and tested using an actual building (i.e., the Churchville Building located at the Aberdeen Proving Ground) and release scenario (i.e., the release and measurement of tracer materials within the building) to ensure realism and practicality in the design and development of the prototype system. A user-friendly "demo" accompanies this report to allow the reader the opportunity for a "hands on" review of the prototype system's capability.

  18. Application of a systems biology approach to skin allergy risk assessment.

    Science.gov (United States)

    Maxwell, Gavin; Mackay, Cameron

    2008-11-01

    We have developed an in silico model of the induction of skin sensitisation, in order to characterise and quantify the contribution of each pathway to the overall biological process. This analysis has been used to guide our research on skin sensitisation and in vitro test development programmes, and provides a theoretical rationale for the interpretation and integration of non-animal predictive data for risk assessment (RA) purposes. The in vivo mouse Local Lymph Node Assay (LLNA) is now in widespread use for the evaluation of skin sensitisation potential and potency. Recent changes in European Union (EU) legislation (i.e. the 7th Amendment to the EU Cosmetics Directive) have made the development of nonanimal approaches to provide the data for skin sensitisation RA a key business need. Several in vitro predictive assays have already been developed for the prediction of skin sensitisation. However, these are based on the determination of a small number of pathways within the overall biological process, and our understanding of the relative contribution of these individual pathways to skin sensitisation induction is limited. To address this knowledge gap, a "systems biology" approach has been used to construct a computer-based mathematical model of the induction of skin sensitisation, in collaboration with Entelos, Inc. The biological mechanisms underlying the induction phase of skin sensitisation are represented by nonlinear ordinary differential equations and defined by using information from over 500 published papers. By using the model, we have identified knowledge gaps for future investigative research, and key factors that have a major influence on the induction of skin sensitisation (e.g. TNF-alpha production in the epidermis). The relative contribution of each of these key pathways has been assessed by determining their contributions to the overall process (e.g. sensitiser-specific T-cell proliferation in the draining lymph node). This information provides a

  19. Biological exposure assessment to tetrachloroethylene for workers in the dry cleaning industry

    Directory of Open Access Journals (Sweden)

    Ashley David L

    2008-04-01

    Full Text Available Abstract Background The purpose of this study was to assess the feasibility of conducting biological tetrachloroethylene (perchloroethylene, PCE exposure assessments of dry cleaning employees in conjunction with evaluation of possible PCE health effects. Methods Eighteen women from four dry cleaning facilities in southwestern Ohio were monitored in a pilot study of workers with PCE exposure. Personal breathing zone samples were collected from each employee on two consecutive work days. Biological monitoring included a single measurement of PCE in blood and multiple measurements of pre- and post-shift PCE in exhaled breath and trichloroacetic acid (TCA in urine. Results Post-shift PCE in exhaled breath gradually increased throughout the work week. Statistically significant correlations were observed among the exposure indices. Decreases in PCE in exhaled breath and TCA in urine were observed after two days without exposure to PCE. A mixed-effects model identified statistically significant associations between PCE in exhaled breath and airborne PCE time weighted average (TWA after adjusting for a random participant effect and fixed effects of time and body mass index. Conclusion Although comprehensive, our sampling strategy was challenging to implement due to fluctuating work schedules and the number (pre- and post-shift on three consecutive days and multiplicity (air, blood, exhaled breath, and urine of samples collected. PCE in blood is the preferred biological index to monitor exposures, but may make recruitment difficult. PCE TWA sampling is an appropriate surrogate, although more field intensive. Repeated measures of exposure and mixed-effects modeling may be required for future studies due to high within-subject variability. Workers should be monitored over a long enough period of time to allow the use of a lag term.

  20. Bibliographical database of radiation biological dosimetry and risk assessment: Part 2

    International Nuclear Information System (INIS)

    This is part 11 of a database constructed to support research in radiation biological dosimetry and risk assessment. Relevant publications were identified through detailed searches of national and international electronic databases and through our personal knowledge of the subject. Publications were numbered and key worded, and referenced in an electronic data-retrieval system that permits quick access through computerized searches on authors, key words, title, year, journal name, or publication number. Photocopies of the publications contained in the database are maintained in a file that is numerically arranged by our publication acquisition numbers. This volume contains 1048 additional entries, which are listed in alphabetical order by author. The computer software used for the database is a simple but sophisticated relational database program that permits quick information access, high flexibility, and the creation of customized reports. This program is inexpensive and is commercially available for the Macintosh and the IBM PC. Although the database entries were made using a Macintosh computer, we have the capability to convert the files into the IBM PC version. As of this date, the database cites 2260 publications. Citations in the database are from 200 different scientific journals. There are also references to 80 books and published symposia, and 158 reports. Information relevant to radiation biological dosimetry and risk assessment is widely distributed within the scientific literature, although a few journals clearly predominate. The journals publishing the largest number of relevant papers are Health Physics, with a total of 242 citations in the database, and Mutation Research, with 185 citations. Other journals with over 100 citations in the database, are Radiation Research, with 136, and International Journal of Radiation Biology, with 132

  1. Design Tools to Assess Hydro-Turbine Biological Performance: Priest Rapids Dam Turbine Replacement Project

    Energy Technology Data Exchange (ETDEWEB)

    Richmond, Marshall C.; Rakowski, Cynthia L.; Serkowski, John A.; Strickler, Brad; Weisbeck, Molly; Dotson, Curtis L.

    2013-06-25

    Over the past two decades, there have been many studies describing injury mechanisms associated with turbine passage, the response of various fish species to these mechanisms, and the probability of survival through dams. Although developing tools to design turbines that improve passage survival has been difficult and slow, a more robust quantification of the turbine environment has emerged through integrating physical model data, fish survival data, and computational fluid dynamics (CFD) studies. Grant County Public Utility District (GCPUD) operates the Priest Rapids Dam (PRD), a hydroelectric facility on the Columbia River in Washington State. The dam contains 10 Kaplan-type turbine units that are now almost 50 years old. The Utility District plans to refit all of these aging turbines with new turbines. The Columbia River at PRD is a migratory pathway for several species of juvenile and adult salmonids, so passage of fish through the dam is a major consideration when replacing the turbines. In this presentation, a method for turbine biological performance assessment (BioPA) is introduced. Using this method, a suite of biological performance indicators is computed based on simulated data from a CFD model of a proposed turbine design. Each performance indicator is a measure of the probability of exposure to a certain dose of an injury mechanism. Using known relationships between the dose of an injury mechanism and frequency of injury (dose–response) from laboratory or field studies, the likelihood of fish injury for a turbine design can be computed from the performance indicator. By comparing the values of the indicators from proposed designs, the engineer can identify the more-promising alternatives. We will present application of the BioPA method for baseline risk assessment calculations for the existing Kaplan turbines at PRD that will be used as the minimum biological performance that a proposed new design must achieve.

  2. DOE SBIR Phase II Final Technical Report - Assessing Climate Change Effects on Wind Energy

    Energy Technology Data Exchange (ETDEWEB)

    Whiteman, Cameron; Capps, Scott

    2014-11-05

    Specialized Vertum Partners software tools were prototyped, tested and commercialized to allow wind energy stakeholders to assess the uncertainties of climate change on wind power production and distribution. This project resulted in three commercially proven products and a marketing tool. The first was a Weather Research and Forecasting Model (WRF) based resource evaluation system. The second was a web-based service providing global 10m wind data from multiple sources to wind industry subscription customers. The third product addressed the needs of our utility clients looking at climate change effects on electricity distribution. For this we collaborated on the Santa Ana Wildfire Threat Index (SAWTi), which was released publicly last quarter. Finally to promote these products and educate potential users we released “Gust or Bust”, a graphic-novel styled marketing publication.

  3. Interactions of physical, chemical, and biological weather calling for an integrated approach to assessment, forecasting, and communication of air quality.

    Science.gov (United States)

    Klein, Thomas; Kukkonen, Jaakko; Dahl, Aslög; Bossioli, Elissavet; Baklanov, Alexander; Vik, Aasmund Fahre; Agnew, Paul; Karatzas, Kostas D; Sofiev, Mikhail

    2012-12-01

    This article reviews interactions and health impacts of physical, chemical, and biological weather. Interactions and synergistic effects between the three types of weather call for integrated assessment, forecasting, and communication of air quality. Today's air quality legislation falls short of addressing air quality degradation by biological weather, despite increasing evidence for the feasibility of both mitigation and adaptation policy options. In comparison with the existing capabilities for physical and chemical weather, the monitoring of biological weather is lacking stable operational agreements and resources. Furthermore, integrated effects of physical, chemical, and biological weather suggest a critical review of air quality management practices. Additional research is required to improve the coupled modeling of physical, chemical, and biological weather as well as the assessment and communication of integrated air quality. Findings from several recent COST Actions underline the importance of an increased dialog between scientists from the fields of meteorology, air quality, aerobiology, health, and policy makers.

  4. Environmental assessment for final rule on nuclear power plant license renewal

    International Nuclear Information System (INIS)

    The Atomic Energy Act and Nuclear Regulatory Commission (NRC) regulations provide for the renewal of nuclear power plant operating licenses beyond their initial 40-year term. The Act and NRC regulations, however, do not specify the procedures, criteria, and standards that must be satisfied in order to renew a license. The NRC is promulgating a rule (10 CFR Part 54) to codify such requirements prior to the receipt of applications for license renewal. The NRC has assessed the possible environmental effects of promulgating requirements in 10 CFR Part 54 now rather than employing such requirements in an ad hoc manner in individual licensing actions. The final part 54 rule requires the development of information and analyses to identify aging problems of systems, structures, and components unique to license renewal that will be of concern during the period of extended operation and will not be controlled by existing effective programs. In general, licensee activities for license renewal may involve replacement, refurbishment, inspection, testing, or monitoring. Such actions will be generally be within the range of similar actions taken for plants during the initial operating term. These actions would be primarily confined within the plants with potential for only minor disruption to the environment. It is unlikely that these actions would change the operating conditions of plants in ways that would change the environmental effects already being experienced. Relicensing under existing regulations would also be primarily focused on aging degradation and would likely result in requirements similar to those that will result from relicensing under the final rule

  5. Assessing Assessment: How Use of the Concept Inventory of Natural Selection Influences the Instructional Practices of an Experienced Biology Professor and Supplemental Instruction Leader

    Science.gov (United States)

    Vanmali, Binaben H.

    2012-01-01

    Assessment has garnered increased interest in recent years. It is seen as critical to enhancing student learning and understanding. Formative assessment tools such as concept inventories could be valuable in moving toward such goals. Concept inventories, a recent addition to biology education, hold much promise for helping faculty to understand…

  6. Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assessment

    Directory of Open Access Journals (Sweden)

    Manzini Giovanni

    2007-07-01

    Full Text Available Abstract Background Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. However, the alignment methods seem inadequate for post-genomic studies since they do not scale well with data set size and they seem to be confined only to genomic and proteomic sequences. Therefore, alignment-free similarity measures are actively pursued. Among those, USM (Universal Similarity Metric has gained prominence. It is based on the deep theory of Kolmogorov Complexity and universality is its most novel striking feature. Since it can only be approximated via data compression, USM is a methodology rather than a formula quantifying the similarity of two strings. Three approximations of USM are available, namely UCD (Universal Compression Dissimilarity, NCD (Normalized Compression Dissimilarity and CD (Compression Dissimilarity. Their applicability and robustness is tested on various data sets yielding a first massive quantitative estimate that the USM methodology and its approximations are of value. Despite the rich theory developed around USM, its experimental assessment has limitations: only a few data compressors have been tested in conjunction with USM and mostly at a qualitative level, no comparison among UCD, NCD and CD is available and no comparison of USM with existing methods, both based on alignments and not, seems to be available. Results We experimentally test the USM methodology by using 25 compressors, all three of its known approximations and six data sets of relevance to Molecular Biology. This offers the first systematic and quantitative experimental assessment of this methodology, that naturally complements the many theoretical and the preliminary experimental results available. Moreover, we compare the USM methodology both with methods based on alignments and not. We may group our experiments into two sets. The first one, performed via ROC

  7. Trade sustainability impact assessment (SIA) on the comprehensive economic and trade agreement (CETA) between the EU and Canada: Final report

    OpenAIRE

    Kirkpatrick, Colin; Raihan, Selim; Bleser, Adam; Prud'homme, Dan; Mayrand, Karel; Morin, Jean Frederic; Pollitt, Hector; Hinojosa, Leonith; Williams, Michael

    2011-01-01

    Commissioned by the European Commission, the Final Report for the EU-Canada Sustainability Impact Assessment (SIA) on the EU-Canada Comprehensive Economic and Trade Agreement (CETA) provides a comprehensive assessment of the potential impacts of trade liberalisation under CETA. The analysis assesses the economic, social and environmental impacts in Canada and the European Union in three main sectors, sixteen sub-sectors and across seven cross-cutting issues. It predicts a number of macro-...

  8. Statistical and regulatory considerations in assessments of interchangeability of biological drug products.

    Science.gov (United States)

    Tóthfalusi, Lászlo; Endrényi, László; Chow, Shein-Chung

    2014-05-01

    When the patent of a brand-name, marketed drug expires, new, generic products are usually offered. Small-molecule generic and originator drug products are expected to be chemically identical. Their pharmaceutical similarity can be typically assessed by simple regulatory criteria such as the expectation that the 90% confidence interval for the ratio of geometric means of some pharmacokinetic parameters be between 0.80 and 1.25. When such criteria are satisfied, the drug products are generally considered to exhibit therapeutic equivalence. They are then usually interchanged freely within individual patients. Biological drugs are complex proteins, for instance, because of their large size, intricate structure, sensitivity to environmental conditions, difficult manufacturing procedures, and the possibility of immunogenicity. Generic and brand-name biologic products can be expected to show only similarity but not identity in their various features and clinical effects. Consequently, the determination of biosimilarity is also a complicated process which involves assessment of the totality of the evidence for the close similarity of the two products. Moreover, even when biosimilarity has been established, it may not be assumed that the two biosimilar products can be automatically substituted by pharmacists. This generally requires additional, careful considerations. Without declaring interchangeability, a new product could be prescribed, i.e. it is prescribable. However, two products can be automatically substituted only if they are interchangeable. Interchangeability is a statistical term and it means that products can be used in any order in the same patient without considering the treatment history. The concepts of interchangeability and prescribability have been widely discussed in the past but only in relation to small molecule generics. In this paper we apply these concepts to biosimilars and we discuss: definitions of prescribability and interchangeability and

  9. Evaluation of Formative Computer-Based Assessment by Cell Biology Students with Differing Entry Qualifications and Ethnicity

    Science.gov (United States)

    Bax, Christopher; Baggott, Glenn; Howey, Ellen; Pellet-Many, Carolyn; Rayne, Richard; Neonaki, Maria; Bax, Bridget E.; White, Christopher Branford

    2006-01-01

    This study was carried out to examine students' responses to the use of on-line assessments that included feedback. First year BSc students taking a Cell Biology module undertook such an assessment and were then asked to evaluate the test by completing an anonymous questionnaire. Answers were analysed in light of the respondents' ethnicity and…

  10. 76 FR 4859 - Availability of an Environmental Assessment and Finding of No Significant Impact for a Biological...

    Science.gov (United States)

    2011-01-27

    ... Animal and Plant Health Inspection Service Availability of an Environmental Assessment and Finding of No Significant Impact for a Biological Control Agent for Asian Citrus Psyllid AGENCY: Animal and Plant Health... Health Inspection Service has prepared an environmental assessment and finding of no significant...

  11. "Capping Off" the Development of Graduate Capabilities in the Final Semester Unit for Biological Science Students: Review and Recommendations

    Science.gov (United States)

    Firn, Jennifer

    2015-01-01

    Biology is the most rapidly evolving scientific field of the 21st century. Biology graduates must be able to integrate concepts and collaborate outside their discipline to solve the most pressing questions of our time, e.g. world hunger, malnutrition, climate change, infectious disease and biosecurity. University educators are attempting to…

  12. Radiation damage and repair in cells and cell components. Part 2. Physical radiations and biological significance. Final report

    International Nuclear Information System (INIS)

    The report comprises a teaching text, encompassing all physical radiations likely to be of biological interest, and the relevant biological effects and their significance. Topics include human radiobiology, delayed effects, radiation absorption in organisms, aqueous radiation chemistry, cell radiobiology, mutagenesis, and photobiology

  13. A technical review and assessment of the BEIR V [Biological Effects of Ionizing Radiation V] report

    International Nuclear Information System (INIS)

    This report was prepared by the DOE BEIR V Technical Review Committee (TRC) to provide a technical review and assessment of the National Research Council's Bilogical Effects of Ionizing Radiation (BEIR) Committee's Report entitled ''Health Effects of Exposure to Low Levels of Ionizing Radiation'' (BEIR V). This report contains seven sections. The first section serves as an introduction and reviews the charge to the TRC. The second section is a chapter-by- chapter summary of the BEIR V Report. The third section is a summary of the risk estimates and conclusions of the BEIR V Committee for genetic effects, cancer induction, and in utero effects. The fourth section is a summary and analysis of the new scientific information used by the BEIR V Committee in developing its risk recommendations and conclusions. The fifth section is an assessment of the scientific information and methods used by the BEIR V Committee in developing their risk estimates and conclusions and an analysis of the key assumptions underlying the use of these risk estimates in risk assessment. The sixth section is the TRC'S assessment of the regulatory implications of the BEIR V risk estimates and conclusions for DOE nuclear operations. The seventh and final section is the TRC'S recommended actions for DOE's consideration concerning the BEIR V Report risk estimates and conclusions. 23 refs., 5 tabs

  14. 合成生物学生物安全风险评价与管理%Assessment and management of biosafety in synthetic biology

    Institute of Scientific and Technical Information of China (English)

    关正君; 裴蕾; 马库斯·施密特; 魏伟

    2012-01-01

    While having developed into one of the most dynamic fields of the life sciences, synthetic biology may pose potential risks to the environment and human health. Based on current national and international risk assessment methods and current regulation of synthetic biology, we reviewed risk assessment in relation to synthetic biology's research subfields (such as DNA-based biocircuits, minimal genome, protocells and chemical synthetic biology), its relation with biosafety engineering, its effect on ELSI (Ethics, Legal and Social Implications) and recent biosecurity challenges, such as biopunk (or biohackery), garage biology, do-it-yourself biology and bioterrorism. Additionally, we investigated existing strategies for management of synthetic biology research, focusing on self-regulatory or technology-focused methods and using the 5P (the principal investigator, the project, the premises, the provider of genetic material and its purchaser) strategy focusing in five different policy intervention points. Furthermore, we reviewed the current research and development of synthetic biology and its current biosafety regulations in China. Finally, we recommended management strategies to guide future research in synthetic biology with necessary amendments, including the establishment of regulations with a core of safety assessment, synthetic biology-specific good laboratory practice guidelines, and arguments for the reinforcement of internal regulation at the institution level and more active public outreach efforts for biosafety.%合成生物学(synthetic biology)已迅速发展为生命科学最具发展潜力的分支学科之一,但它同时也会给生态环境和人类健康带来潜在的风险.结合国内外合成生物学发展现状,本文综述了基因回路(DNA-based biocircuits)、最小基因组(minimal genome)、原型细胞(protocells)、化学合成生物学(chemical synthetic biology)等涉及的风险评价、合成生

  15. Biological assessments for the low energy demonstration accelerator, 1996 and 1997

    Energy Technology Data Exchange (ETDEWEB)

    Cross, S.

    1998-12-31

    The Department of Energy (DOE) plans to build, install, and operate a Low Energy Demonstration Accelerator (LMA) in Technical Area 53 of the Los Alamos National Laboratory (LANL). LEDA will demonstrate the accelerator technology necessary to produce tritium, but is not designed to produce tritium at LANL. USFWS reviewers of the Biological Assessment prepared for LEDA insisted that the main drainage be monitored to measure and document changes to vegetation, soils, wildlife, and habitats due to LEDA effluent discharges. The Biology Team of ESH-20 (LANL`s Ecology Group) has performed these monitoring activities during 1996 and 1997 to document baseline conditions before LEDA released significant effluent discharges. Quarterly monitoring of the outfall which will discharge LEDA blowdown effluent had one exceedance of permitted parameters, a high chlorine discharge that was quickly remedied. Samples from 12 soil pits in the drainage area contained no hydric indicators, such as organic matter in the upper layers, streaking, organic pans, and oxidized rhizospheres. Vegetation transacts in the meadows that LEDA discharges will flow through contained 44 species of herbaceous plants, all upland taxa. Surveys of resident birds, reptiles, and amphibians documented a fauna typical of local dry canyons. No threatened or endangered species inhabit the project area, but increased effluent releases may make the area more attractive to many wildlife species, an endangered raptor, and several other species of concern. Biological best management practices especially designed for LEDA are discussed, including protection of floodplains, erosion control measures, hazards posed by increased usage of the area by deer and elk and revegetation of disturbed areas.

  16. Biological assessment of contaminated land using earthworm biomarkers in support of chemical analysis

    International Nuclear Information System (INIS)

    Biological indicators can be used to assess polluted sites but their success depends on the availability of suitable assays. The aim of this study was to investigate the performance of two earthworm biomarkers, lysosomal membrane stability measured using the neutral red retention assay (NRR-T) and the total immune activity (TIA) assay, that have previously been established as responsive to chemical exposure. Responses of the two assays were measured following in situ exposure to complexly contaminated field soils at three industrial sites as well as urban and rural controls. The industrial sites were contaminated with a range of metal (cadmium, copper, lead, zinc, nickel and cobalt) and organic (including polycyclic aromatic hydrocarbons) contaminants, but at concentrations below the 'New Dutch List' Intervention concentrations. Exposed earthworms accumulated both metals and organic compounds at the contaminated sites, indicating that there was significant exposure. No effect on earthworm survival was found at any of the sites. Biomarker measurements, however, indicated significant effects, with lower NRR-T and TIA found in the contaminated soils when compared to the two controls. The results demonstrate that a comparison of soil pollutant concentrations with guideline values would not have unequivocally identified chemical exposure and toxic effect for soil organisms living in these soils. However, the earthworm biomarkers successfully identified significant exposure and biological effects caused by the mixture of chemicals present

  17. Mass balance to assess the efficiency of a mechanical-biological treatment

    International Nuclear Information System (INIS)

    Using mechanical-biological treatment of residual municipal solid waste, it is possible to significantly lower landfill volume and gas and leachate emissions. Moreover, the landfill characteristics are improved. The performance of the Mende (France) mechanical-biological treatment plant is assessed via mass balances coupled with manual sorting according to the MODECOMTM methodology and biochemical methane potential after 90 days of incubation. The site includes mechanical sorting operations, a rotary sequential bioreactor, controlled aerobic stabilisation corridors, maturation platforms, and a sanitary landfill site for waste disposal in separated cells. Results showed that several steps could be improved: after a first sieving step, about 12% of the potentially biodegradable matter is landfilled directly without any treatment; mechanical disintegration of papers and cardboards in the rotary sequential bioreactor is insufficient and leads to a high proportion of papers and cardboards being landfilled without further treatment. Two fine fractions go through stabilisation and maturation steps. At the end of the maturation step, about 54% of the potentially biodegradable matter is degraded. The biochemical methane potential after 90 days of incubation is reduced by 81% for one of the two fine fractions and reduced by 88% for the other one. Considering the whole plant, there is a reduction of nearly 20% DM of the entering residual municipal solid waste

  18. OPTIMIZATION OF WHEAT BRAN MEDIUM PROCESSING CONDITIONS, ASSESSMENT OF BIOLOGICAL VALUE FOR SACCHAROMYCES

    Directory of Open Access Journals (Sweden)

    Victor Panfilov

    2015-09-01

    Full Text Available Biotechnological methods have perhaps the greatest potential in deep processing of renewable raw materials. Bioconversion of lignocelluloses materials substantially increases its bioavailability and effectiveness of consumption by microorganisms. The enzymatic and chemical hydrolysis of wheat bran under mild conditions are compared in this study.The purpose of this study was to define microbiological and biochemical criteria for the bioconversion. Enzymatic hydrolysis of extruded bran was held with three enzyme preparations usually used in the conversion of vegetable raw materials: “Viscoferm,” “Cellic HTec2,” and “Celloviridin G20x.” The central composite design was used for parameter optimization. Saccharomyces cerevisiae yeast was used for assessment of biological value of the slurry obtained. The content of crude protein of the product obtained was 1.9 times higher than the initial.

  19. Assessing the Soil Physiological Potential Using Pedo-Biological Diagnosis Under Minimum-Tillage System and Mineral Fertilization

    OpenAIRE

    Lazar Bireescu; Geanina Bireescu; Michele Vincenzo Sellitto

    2014-01-01

    The main objective of sustainable agriculture is the protection of environment and natural vegetal and soil resources. Accordingly, the objective of this research was to assess the impact of technological systems by minimum tillage on soil biological activity, using the Pedo-Biological Diagnosis of Soil Resources. Our research was conducted on haplic chernozem from Experimental Station of UASVM of Iasi, Romania, during the seasonal dynamic, to the soybean crop, on unfertilized and fertilized ...

  20. Assessment of the Effects of Student Response Systems on Student Learning and Attitudes over a Broad Range of Biology Courses

    OpenAIRE

    Preszler, Ralph W.; Dawe, Angus; Shuster, Charles B.; Shuster, Michèle

    2007-01-01

    With the advent of wireless technology, new tools are available that are intended to enhance students' learning and attitudes. To assess the effectiveness of wireless student response systems in the biology curriculum at New Mexico State University, a combined study of student attitudes and performance was undertaken. A survey of students in six biology courses showed that strong majorities of students had favorable overall impressions of the use of student response systems and also thought t...

  1. Biological methods for increasing the biogas yield of livestock waste. Final report; Biologiske metoder til foroegelse af husdyrgoednings biogaspotentiale. Slutrapport

    Energy Technology Data Exchange (ETDEWEB)

    Mladenovska, Z.; Ahring, B.K.

    2001-01-01

    Danish full-scale biogas plants operate with manure as a primary substrate, of which cattle manure represents a significant fraction. Conversion of the lignocellulosic fibre fraction of manure was shown to be the rate-degrading step of the anaerobic digestion. The aim of this project was to investigate if the biological methods, such as bioaugmentation of the reactor with specific anaerobic, hydrolytic bacteria would improve hydrolysis of fibres and result in an increase of the methane yield of cattle manure. Results of this study showed, that there is a potential for an increase of the methane yield of manure by inoculating the fibre-containing substrate with cellulose- and alkaliphilic xylane-hydrolyzing bacterial cultures. The highest increase of methane yield in batch experiment was obtained at 37 deg. C and 68 deg. C, while the effect at 55 deg. C was poor. Direct inoculation of a mesophilic reactor with Clostridium cellulovorans (DSM 3052) was not successful. The fate of the organism, followed by 16S rRNA probing, proved that DSM 3052 was not a member of the indigenous microflora, and that the active population of DSM 3052 could not be established within the reactor. On the other hand, inoculation of a reactor with our own isolate, a new clostridial strain, Clostridium sp. SA 14, resulted in a significant increase of the methane yield from 220 ml CH{sub 4}/g VS up to 330 ml CH{sub 4}/g VS. However, during the continuous reactor operation in the period of one retention time, the effect was reduced and finally disappeared. Therefore, it would be necessary in the future to develop a new strategy for establishment of this strain within the reactor environment. Anaerobic digestion of manure was also studied in a two-step process, where manure was first hydrolyzed at 68 deg. C, and thereafter digested in a conventional methanogenic step at 55 deg. C. Investigation from batch experiment resulted in a 24%- increase in methane yield for the two-step digestion compared

  2. Asteroid Redirect Mission (ARM) Formulation Assessment and Support Team (FAST) Final Report

    Science.gov (United States)

    Mazanek, Daniel D.; Reeves, David M.; Abell, Paul A.; Asphaug, Erik; Abreu, Neyda M.; Bell, James F.; Bottke, William F.; Britt, Daniel T.; Campins, Humberto; Chodas, Paul W.; Ernst, Carolyn M.; Fries, Marc D.; Gertsch, Leslie S.; Glavin, Daniel P.; Hartzell, Christine M.; Hendrix, Amanda R.; Nuth, Joseph A.; Scheeres, Daniel J.; Sercel, Joel C.; Takir, Driss; Zacny, Kris

    2016-01-01

    The Asteroid Redirect Mission (ARM) Formulation Assessment and Support Team (FAST) was a two-month effort, chartered by NASA, to provide timely inputs for mission requirement formulation in support of the Asteroid Redirect Robotic Mission (ARRM) Requirements Closure Technical Interchange Meeting held December 15-16, 2015, to assist in developing an initial list of potential mission investigations, and to provide input on potential hosted payloads and partnerships. The FAST explored several aspects of potential science benefits and knowledge gain from the ARM. Expertise from the science, engineering, and technology communities was represented in exploring lines of inquiry related to key characteristics of the ARRM reference target asteroid (2008 EV5) for engineering design purposes. Specific areas of interest included target origin, spatial distribution and size of boulders, surface geotechnical properties, boulder physical properties, and considerations for boulder handling, crew safety, and containment. In order to increase knowledge gain potential from the mission, opportunities for partnerships and accompanying payloads were also investigated. Potential investigations could be conducted to reduce mission risks and increase knowledge return in the areas of science, planetary defense, asteroid resources and in-situ resource utilization, and capability and technology demonstrations. This report represents the FASTâ€"TM"s final product for the ARM.

  3. Assessing Impacts of Climate Change on Forests: The State of Biological Modeling

    Science.gov (United States)

    Dale, V. H.; Rauscher, H. M.

    1993-04-06

    Models that address the impacts to forests of climate change are reviewed by four levels of biological organization: global, regional or landscape, community, and tree. The models are compared as to their ability to assess changes in greenhouse gas flux, land use, maps of forest type or species composition, forest resource productivity, forest health, biodiversity, and wildlife habitat. No one model can address all of these impacts, but landscape transition models and regional vegetation and land-use models consider the largest number of impacts. Developing landscape vegetation dynamics models of functional groups is suggested as a means to integrate the theory of both landscape ecology and individual tree responses to climate change. Risk assessment methodologies can be adapted to deal with the impacts of climate change at various spatial and temporal scales. Four areas of research development are identified: (1) linking socioeconomic and ecologic models, (2) interfacing forest models at different scales, (3) obtaining data on susceptibility of trees and forest to changes in climate and disturbance regimes, and (4) relating information from different scales.

  4. Assessing impacts of climate change on forests: The state of biological modeling

    Energy Technology Data Exchange (ETDEWEB)

    Dale, V.H. [Oak Ridge National Lab., TN (United States); Rauscher, H.M. [Forest Service, Grand Rapids, MI (United States). North Central Forest Experiment Station

    1993-04-06

    Models that address the impacts to forests of climate change are reviewed by four levels of biological organization: global, regional or landscape, community, and tree. The models are compared as to their ability to assess changes in greenhouse gas flux, land use, maps of forest type or species composition, forest resource productivity, forest health, biodiversity, and wildlife habitat. No one model can address all of these impacts, but landscape transition models and regional vegetation and land-use models consider the largest number of impacts. Developing landscape vegetation dynamics models of functional groups is suggested as a means to integrate the theory of both landscape ecology and individual tree responses to climate change. Risk assessment methodologies can be adapted to deal with the impacts of climate change at various spatial and temporal scales. Four areas of research development are identified: (1) linking socioeconomic and ecologic models, (2) interfacing forest models at different scales, (3) obtaining data on susceptibility of trees and forest to changes in climate and disturbance regimes, and (4) relating information from different scales.

  5. The Role of Reference Condition in Biological Assessment and Criteria: An EPA Guidance Document

    Science.gov (United States)

    Southerland, M. T.; Larsen, D. P.; Davis, W. S.

    2005-05-01

    The U.S. Environmental Protection Agency is preparing a document to provide States, Tribes, and other practitioners with guidelines on the reference condition concept and how to apply it in their water management programs, particularly for assessing the condition of aquatic resources. These guidelines are intended to broaden the implementation of biological monitoring and assessment, to increase the consistency among States and Tribes, and to improve the success of individual programs. Establishing and using the reference condition concept appropriately is critical to implementing biocriteria and tiered aquatic life uses to protect and restore water resource quality. This document will cover the following topics: a description of the concept of reference condition and related concepts (including minimally disturbed, least disturbed, and attainable conditions); methods for characterizing reference and related conditions; the role of water body classification to partition natural variability; setting thresholds to determine achievement of a target condition; and application of the concept in heavily modified regions (e.g., urban landscapes; agricultural regions) and waterbodies (reservoirs, regulated rivers). A section on frequently asked questions and answers is included. Throughout the document, examples are drawn from existing State and Tribal programs to illustrate specific applications that are consistent with the guidelines.

  6. Interlaboratory comparison of size and surface charge measurements on nanoparticles prior to biological impact assessment

    International Nuclear Information System (INIS)

    The International Alliance for NanoEHS Harmonization (IANH) organises interlaboratory comparisons of methods used to study the potential biological impacts of nanomaterials. The aim of IANH is to identify and reduce or remove sources of variability and irreproducibility in existing protocols. Here, we present results of the first IANH round robin studies into methods to assess the size and surface charge of suspended nanoparticles. The test materials used (suspensions of gold, silica, polystyrene, and ceria nanoparticles, with [primary] particles sizes between 10 nm and 80 nm) were first analysed in repeatability conditions to assess the possible contribution of between-sample heterogeneity to the between-laboratory variability. Reproducibility of the selected methods was investigated in an interlaboratory comparison between ten different laboratories in the USA and Europe. Robust statistical analysis was used to evaluate within- and between-laboratory variability. It is shown that, if detailed shipping, measurement, and reporting protocols are followed, measurement of the hydrodynamic particle diameter of nanoparticles in predispersed monomodal suspensions using the dynamic light scattering method is reproducible. On the other hand, measurements of more polydisperse suspensions of nanoparticle aggregates or agglomerates were not reproducible between laboratories. Ultrasonication, which is commonly used to prepare dispersions before cell exposures, was observed to further increase variability. The variability of the zeta potential values, which were also measured, indicates the need to define better surface charge test protocols and to identify sources of variability.

  7. Biological assessment for the remedial action at the chemical plant area of the Weldon Spring site

    Energy Technology Data Exchange (ETDEWEB)

    Hlohowskyj, I.; Dunn, C.P.

    1992-11-01

    The Weldon Spring site in St.Charles County, Missouri, became contaminated during the 1940s through the 1960s as a result of explosives production by the US Army and uranium and thorium processing by the predecessor agency of the US Department of Energy (DOE). The site is listed on the National Priorities List of the US Environmental Protection Agency, and DOE is responsible for its cleanup. Contaminants are present in soil, surface water, and aquatic sediments. Alternatives identified for site remediation are no action (included as baseline for comparison), treatment and disposal of the wastes at the Weldon Spring site, and on-site treatment followed by off-site disposal at either a commercial facility near Clive, Utah, or at DOE's Hanford site near Richland, Washington. In accordance with the requirements of the Endangered Species Act, this biological assessment has been prepared to evaluate the potential effects of proposed remedial action alternatives on federal listed (endangered or threatened) and candidate species at the respective sites. The assessment includes consideration of the environmental setting at each site; the federal listed and candidate species that could occur at each site; the construction, excavation, and treatment activities under each alternative; and the amount of land area affected at each site.

  8. Biological assessment for the remedial action at the chemical plant area of the Weldon Spring site

    Energy Technology Data Exchange (ETDEWEB)

    Hlohowskyj, I.; Dunn, C.P.

    1992-11-01

    The Weldon Spring site in St.Charles County, Missouri, became contaminated during the 1940s through the 1960s as a result of explosives production by the US Army and uranium and thorium processing by the predecessor agency of the US Department of Energy (DOE). The site is listed on the National Priorities List of the US Environmental Protection Agency, and DOE is responsible for its cleanup. Contaminants are present in soil, surface water, and aquatic sediments. Alternatives identified for site remediation are no action (included as baseline for comparison), treatment and disposal of the wastes at the Weldon Spring site, and on-site treatment followed by off-site disposal at either a commercial facility near Clive, Utah, or at DOE`s Hanford site near Richland, Washington. In accordance with the requirements of the Endangered Species Act, this biological assessment has been prepared to evaluate the potential effects of proposed remedial action alternatives on federal listed (endangered or threatened) and candidate species at the respective sites. The assessment includes consideration of the environmental setting at each site; the federal listed and candidate species that could occur at each site; the construction, excavation, and treatment activities under each alternative; and the amount of land area affected at each site.

  9. Removal of Review and Reclassification Procedures for Biological Products Licensed Prior to July 1, 1972. Final rule.

    Science.gov (United States)

    2016-02-12

    The Food and Drug Administration (FDA, the Agency, or we) is removing two regulations that prescribe procedures for FDA's review and classification of biological products licensed before July 1, 1972. FDA is taking this action because the two regulations are obsolete and no longer necessary in light of other statutory and regulatory authorities established since 1972, which allow FDA to evaluate and monitor the safety and effectiveness of all biological products. In addition, other statutory and regulatory authorities authorize FDA to revoke a license for biological products because they are not safe and effective, or are misbranded. FDA is taking this action as part of its retrospective review of its regulations to promote improvement and innovation. PMID:26878738

  10. Horns Rev offshore wind farm. Environmental impact assessment of sea bottom and marine biology

    Energy Technology Data Exchange (ETDEWEB)

    Leonhard, S.B.

    2000-03-15

    An Environmental Impact Assessment (EIA) of a planned 150 MW offshore wind farm at Horns Rev has been carried out for the marine biology and sea bottom in the area, and includes vegetation and benthic fauna. The study forms part of a total EIA of the planned offshore wind farm. This EIA study has been drawn up in accordance with the guidelines laid down by the Ministry of Environment and Energy in the publication, 'Guidelines for preparation of EIAstudies for offshore wind farms. Horns Rev is situated off Blaevands Huk, which is Denmark's most westerly point. It is a shallow reef with water depths between 2 and 9 metres and is primarily composed of sand, gravel and pebbles. The area designated for the wind farm lies directly south of Horns Rev and is dominated by sand with a median particle size of 0.3 mm. Along the edges, towards areas of greater depth, the particle size increases. There are areas of fine sand in the deepest area, and in isolated pockets within the proposed wind farm site. The sediment is characterised by a very low (<1%) organic matter content. On the basis of the expected impact from the establishment of the wind farm, it is not deemed necessary to carry out special programmes during the construction phase for monitoring of the environmental-biological conditions. A monitoring and control programme is recommended during the production phase in order to follow the copper concentration in bivalves, or alternatively to initiate recovery or elimination of the copper-laden waste. A control programme is recommended during the production phase in order to follow the establishment and succession of the fouling community on the wind turbine foundations and scour-protecting revetments. (BA)

  11. 78 FR 36743 - Adoption of Final Environmental Assessment (UT-040-09-03) Prepared for the Upper Kanab Creek...

    Science.gov (United States)

    2013-06-19

    ... Natural Resources Conservation Service Adoption of Final Environmental Assessment (UT-040-09-03) Prepared... or postmarked concerning the adoption of this EA at the address below until July 19, 2013. ADDRESSES: You may submit comments concerning the adoption of the Kanab Creek Watershed Vegetation...

  12. 76 FR 12373 - Notice of Availability of Final Supplement to the Environmental Assessment for the Proposed Pa...

    Science.gov (United States)

    2011-03-07

    ... Hawaii, LLC Irradiator in Honolulu, HI AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Final Supplement to the Environmental Assessment (EA) for the irradiator proposed by Pa'ina Hawaii, LLC... from earthquakes, tsunamis, and hurricanes at the alternative locations will be small....

  13. Risk assessment, eradication, and biological control: global efforts to limit Australian acacia invasions

    Science.gov (United States)

    Wilson, John R.U.; Gairifo, Carla; Gibson, Michelle R.; Arianoutsou, Margarita; Bakar, Baki B.; Baret, Stephane; Celesti-Grapow, Laura; DiTomaso, Joseph M.; Dufour-Dror, Jean-Marc; Kueffer, Christoph; Kull, Christian A.; Hoffman, John H.; Impson, Fiona A.C.; Loope, Lloyd L.; Marchante, Elizabete; Harchante, Helia; Moore, Joslin L.; Murphy, Daniel J.; Tassin, Jacques; Witt, Arne; Zenni, Rafael D.; Richardson, David M.

    2011-01-01

    Aim Many Australian Acacia species have been planted around the world, some are highly valued, some are invasive, and some are both highly valued and invasive. We review global efforts to minimize the risk and limit the impact of invasions in this widely used plant group. Location Global. Methods Using information from literature sources, knowledge and experience of the authors, and the responses from a questionnaire sent to experts around the world, we reviewed: (1) a generalized life cycle of Australian acacias and how to control each life stage, (2) different management approaches and (3) what is required to help limit or prevent invasions. Results Relatively few Australian acacias have been introduced in large numbers, but all species with a long and extensive history of planting have become invasive somewhere. Australian acacias, as a group, have a high risk of becoming invasive and causing significant impacts as determined by existing assessment schemes. Moreover, in most situations, long-lived seed banks mean it is very difficult to control established infestations. Control has focused almost exclusively on widespread invaders, and eradication has rarely been attempted. Classical biological control is being used in South Africa with increasing success. Main conclusions A greater emphasis on pro-active rather than reactive management is required given the difficulties managing established invasions of Australian acacias. Adverse effects of proposed new introductions can be minimized by conducting detailed risk assessments in advance, planning for on-going monitoring and management, and ensuring resources are in place for long-term mitigation. Benign alternatives (e.g. sterile hybrids) could be developed to replace existing utilized taxa. Eradication should be set as a management goal more often to reduce the invasion debt. Introducing classical biological control agents that have a successful track-record in South Africa to other regions and identifying new

  14. ICLIPS - integrated assessment of climate protection strategies. Final report; ICLIPS - Integrierte Abschaetzung von Klimaschutzstrategien. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Toth, F.L.; Bruckner, T.; Fuessel, H.M.

    2000-12-01

    The ICLIPs project is connected to the development of integrated climate impact research in Germany. It is concerned not only with a single dimension of possible impacts of climate change, but it also investigates these impacts in the context of adaptation options and mitigation possibilities. The Tolerable Windows Approach (TWA) permits the explicit consideration of both ecological and economic requirements in identifying tolerable climate protection strategies. This way it fulfills the central objective of science policy related to the complex issue of 'Sustainable Growth'. In the project period, the ICLIPS model, a detailed integrated model of global climate change ('Integrated Assessment Model', IAM) was developed in the framework of a successful international cooperation. As a result, climate impact research in Germany succeeded to catch up with the international forefront in a research field that is very important for practical policy advice, and even managed to take a leading role in some important sub-fields. The ICLIPS model contains a series of innovative features that clearly distinguish this model from other intertemporal optimization models. The features worth mentioning here include: a numerically highly efficient climate model that covers all relevant greenhouse gases; a series of Climate Impact Response Functions that depict climate-relevant changes in natural vegetation systems, agricultural yields, and water availability; and finally a model of long-term economic development that explicitly considers the cost-reducing effects of technological learning. (orig.) [German] Das ICLIPS-Projekt bezieht sich auf die Weiterentwicklung der integrierten Klimafolgenforschung in Deutschland, die sich nicht nur eindimensional mit moeglichen Auswirkungen von Klimaveraenderungen beschaeftigt, sondern diese zusammen mit Anpassungsoptionen und Vermeidungsmoeglichkeiten untersucht. Der Fensteransatz, der bei der Identifizierung von tolerierbaren

  15. Implementation and Assessment of a Molecular Biology and Bioinformatics Undergraduate Degree Program

    Science.gov (United States)

    Pham, Daphne Q. -D.; Higgs, David C.; Statham, Anne; Schleiter, Mary Kay

    2008-01-01

    The Department of Biological Sciences at the University of Wisconsin-Parkside has developed and implemented an innovative, multidisciplinary undergraduate curriculum in Molecular Biology and Bioinformatics (MBB). The objective of the MBB program is to give students a hands-on facility with molecular biology theories and laboratory techniques, an…

  16. Isotopic assessment of long term groundwater exploitation. Proceedings of a final research coordination meeting

    International Nuclear Information System (INIS)

    The stress imposed on the available water resources due to man's impact (exploitation, release of pollutants and agricultural practices) has resulted in depletion of the available reserves as well as deterioration of water quality in many parts of the world. Over wide areas, abstractions are exceeding current natural recharge and it is apparent from scientific studies that these water resources are being mined, especially in arid and semi-arid areas. Sustainable development and management of those water resources needs long term monitoring records to understand the changes and dynamic responses due to the exploitation. These proceedings provide a synthesis of a series of hydrochemical, isotope and geohydrological data sets which will be used for quantitative assessment of the long term dynamic response of the groundwater system. The results show that both stable and radioactive isotopes are excellent tools for characterizing and understanding aquifer systems that are undergoing long term exploitation. Specific outcomes include establishment of methodologies for monitoring and predicting changes in water quality and quantity that will lead to improved water resources management. This publication is a summary of the results achieved during the coordinated research project (CRP) and the various studies performed by the participating institutions are presented as individual presentations. The overall achievements are presented as an executive summary, and the detailed findings are presented in each contribution. These results were presented in the final coordination meeting held in Vienna, 12-16 May 2003. The results obtained from this CRP will be used to improve the predictions of future behaviour of groundwater resources in response to exploitation. The scientific component of this CRP will be a valuable source of information for isotope hydrologists involved in isotope field applications and a useful guide for groundwater managers involved in groundwater resources

  17. 75 FR 39039 - Notice of Availability of the Final Environmental Assessment for the Upper Midwest Environmental...

    Science.gov (United States)

    2010-07-07

    ... INFORMATION CONTACT: Mr. Bill Hayman, Facility Mechanical Engineer at Upper Midwest Environmental Sciences... (ultraviolet) equipment for disinfection of final effluent. Repair fence and gates. Repair eroded bank...

  18. Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors: Final Scientific/Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Vierow, Karen; Aldemir, Tunc

    2009-09-10

    The project entitled, “Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors”, was conducted as a DOE NERI project collaboration between Texas A&M University and The Ohio State University between March 2006 and June 2009. The overall goal of the proposed project was to develop practical approaches and tools by which dynamic reliability and risk assessment techniques can be used to augment the uncertainty quantification process in probabilistic risk assessment (PRA) methods and PRA applications for Generation IV reactors. This report is the Final Scientific/Technical Report summarizing the project.

  19. Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors: Final Scientific/Technical Report

    International Nuclear Information System (INIS)

    The project entitled, 'Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors', was conducted as a DOE NERI project collaboration between Texas A and M University and The Ohio State University between March 2006 and June 2009. The overall goal of the proposed project was to develop practical approaches and tools by which dynamic reliability and risk assessment techniques can be used to augment the uncertainty quantification process in probabilistic risk assessment (PRA) methods and PRA applications for Generation IV reactors. This report is the Final Scientific/Technical Report summarizing the project.

  20. Uncertainty Analysis for Peer Assessment: Oral Presentation Skills for Final Year Project

    Science.gov (United States)

    Kim, Ho Sung

    2014-01-01

    Peer assessment plays an important role in engineering education for an active involvement in the assessment process, developing autonomy, enhancing reflection, and understanding of how to achieve the learning outcomes. Peer assessment uncertainty for oral presentation skills as part of the FYP assessment is studied. Validity and reliability for…

  1. How Important Is the Assessment of Practical Work? An Opinion Piece on the New Biology A-Level from BERG

    Science.gov (United States)

    Journal of Biological Education, 2014

    2014-01-01

    As education in England emerges from a major curriculum review (DfE 2013), the next few years will see significant changes in what is taught in schools and how this is assessed. As a core subject, under the current proposals, all students, from the beginning of primary school until age 16, will study science in some detail. Biology is an exciting,…

  2. Exposure assessment to heavy metals in general population in a polluted area through biological monitoring

    Directory of Open Access Journals (Sweden)

    Vimercati L.

    2013-04-01

    Full Text Available In polluted areas, a major issue is the correct assessment of the exposure of general population to industrial pollutants. The objectives were: to evaluate the exposure to heavy metals emitted from the industrial area of Taranto; to correlate biological monitoring data with environmental data, in order to clarify the impact of industrial pollution in terms of internal dose. A cross sectional study has been designed to measure levels of urinary arsenic, lead, cadmium, chromium, manganese in 300 inhabitants of Taranto, Statte and Laterza. Adult subjects have been selected by a two-stage random stratified sampling. Results are based on 272 subjects (131 men and 141 women. The observed concentrations of metals in the whole study population are overall high. The median values for lead (7.4 μg/l and chromium (0.4 μg/l are higher than the 95° percentile of the range of reference values. For manganese and arsenic the 95° percentile of concentration in the whole study population is higher than the 95° percentile of the range of reference values. Concentrations of mercury in the whole study population are comparable to reference.

  3. Characterization of Radiation Fields in Biological Shields of Nuclear Power Plants for Assessing Concrete Degradation

    Science.gov (United States)

    Remec, Igor; Rosseel, Thomas M.; Field, Kevin G.; Le Pape, Yann

    2016-02-01

    Life extensions of nuclear power plants to 60 and potentially 80 years of operation have renewed interest in long-term material degradation. One material being considered is concrete, with a particular focus on radiation-induced effects. Based on the projected neutron fluence values (E > 0.1 MeV) in the concrete biological shields of the US pressurized water reactor fleet and the available data on radiation effects on concrete, some decrease in mechanical properties of concrete cannot be ruled out during extended operation beyond 60 years. An expansion of the irradiated concrete database and a reliable determination of relevant neutron fluence energy cutoff value are necessary to ensure reliable risk assessment for extended operation of nuclear power plants. Notice: This manuscript has been authored by UT-Battelle, LLC, under contract DE-AC0500OR22725 with the US Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a nonexclusive, paid-up, irrevocable, worldwide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes.

  4. Radon as a medicine. Therapeutic effectiveness, biological mechanism and comparative risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Deetjen, Peter; Falkenbach, Albrecht; Harder, Dietrich; Joeckel, Hans; Kaul, Alexander; Philipsborn, Henning von

    2014-07-01

    Proofs of the therapeutic efficiency of balneological radon applications administered to patients suffering from rheumatic diseases, investigations into the biological action mechanism associated with the alpha particles emitted by radon and its radioactive daughter products, and the comparative risk assessment of radon treatment and medicinal pain therapy have been the research projects whose results are summarized in this book. Controlled clinical studies, if possible performed as prospective, randomized and placebo-controlled double blind studies, have given evidence that the therapeutic effects of balneological radon applications - long-lasting pain reduction and reduced consumption of medicines compared with controls - are significantly persisting over many post-treatment months. The molecular and cellular mechanism of action underlying these long-lasting therapeutic effects has been identified as the down-regulation of cellular immune responses, initiated by cellular apoptosis sequential to low alpha particle doses and by the subsequent release of anti-inflammatory cytokines. The unwanted side-effects of non-steroidal anti-rheumatic drug treatments have to be compared with the absence of side effects from the balneological radon applications which merely involve radiation doses well below the mean value and the fluctuation width of the annual doses attributable to everybody's natural radiation exposure.

  5. Assessment of the ecological security of immobilized enzyme remediation process with biological indicators of soil health.

    Science.gov (United States)

    Zhang, Ying; Dong, Xiaonan; Jiang, Zhao; Cao, Bo; Ge, Shijie; Hu, Miao

    2013-08-01

    This study used the enzymes extracted from an atrazine-degrading strain, Arthrobacter sp. DNS10, which had been immobilized by sodium alginate to rehabilitate atrazine-polluted soil. Meanwhile, a range of biological indices were selected to assess the ecological health of contaminated soils and the ecological security of this bioremediation method. The results showed that there was no atrazine detected in soil samples after 28 days in EN+AT (the soil containing atrazine and immobilized enzyme) treatment. However, the residual atrazine concentration of the sample in AT (the soil containing atrazine only) treatment was about 5.02 ± 0.93 mg kg(-1). These results suggest that the immobilized enzyme exhibits an excellent ability in atrazine degradation. Furthermore, the immobilized enzyme could relieve soil microbial biomass carbon and soil microbial respiration intensity to 772.33 ± 34.93 mg C kg(-1) and 5.01 ± 0.17 mg CO(2) g(-1) soil h(-1), respectively. The results of the polymerase chain reaction-degeneration gradient gel electrophoresis experiment indicated that the immobilized enzyme also could make the Shannon-Wiener index and evenness index of the soil sample increase from 1.02 and 0.74 to 1.51 and 0.84, respectively. These results indicated that the immobilized enzymes not only could relieve the impact from atrazine on the soil, but also revealed that the immobilized enzymes did no significant harm on the soil ecological health.

  6. Circulating nucleic acids and hemostasis: biological basis behind their relationship and technical issues in assessment.

    Science.gov (United States)

    Danese, Elisa; Montagnana, Martina; Fava, Cristiano; Guidi, Gian Cesare

    2014-10-01

    Nucleic acids (NAs) constitute the backbone of cellular life permitting conservation, transmission, and execution of genetic information. In the past few years, new unexpected functions for NAs, projecting them also beyond nuclear and cellular boundaries have been recognized: circulating cell-free nucleic acids (cfNAs), histones, DNA-histone complexes, microRNAs (miRs) may have a regulatory role in physiological and pathological processes. In particular, several lines of evidence suggest that they can constitute unconventional mediators of thrombus formation, intervening both in hemostasis and thrombosis. Furthermore, in the past decade, the possibility to detect and quantify these in plasma and/or in serum has led to their ancillary use as potential markers in various medical conditions. The use of these as markers within the fields of thrombosis and hemostasis looks promising: the potential implications include the possibility to assess patients' risk profiles for thrombotic events and the identification of more directed targets for pharmacologic intervention. The major impediment is that, to date, the methods by which NAs are explored, still largely differ between published studies and standardized procedures are still lacking. Future research should focus on the physiological mechanisms underlying the activities of such mediators in specific thrombotic conditions and on the definition of reliable methods for their quantification in biological fluids.

  7. Reproductive Biology of Amblema neislerii, Elliptoideus sloatianus, Lampsilis subangulata, Medionidus penicillatus, and Pleurobema pyriforme (Bivalvia: Unionidae): final report

    OpenAIRE

    O'Brien, Christine

    1997-01-01

    A study on the reproductive biology of Amblema neislerii, Elliptoideus sloatianus, Lampsilis subangulata, Medionidus penicillatus, and Pleurobema pyriforme was conducted from May 1995 to May 1997. The objectives of this study were as follows: 1) determine period of gravidity for each of the five mussel species, 2) determine host fish via laboratory experiments, 3) test whether unionid glochidia will transform on a nonidingenous fish, and 4) describe the glochidial morp...

  8. A review of the known biological characteristics of the Great Meteor East site together with a sampling programme for a biological site assessment

    International Nuclear Information System (INIS)

    Existing biological information on GME is reviewed. In common with most other oceanic areas there is very little data available from depths below 2000m. There is virtually no direct benthic information and none at all on the midwater/benthic boundary layer. Existing data from a wider geographic area are relevant to GME but the applicability of such data varies according to the hydrography. A sampling programme is outlined which will allow a comprehensive quantitative and qualitative assessment of the midwater and benthic ecosystems. Particular attention will be paid to the interactions between benthic and midwater communities just above the sea floor. (author)

  9. Ways of incorporating photographic images in learning and assessing high school biology: A study of visual perception and visual cognition

    Science.gov (United States)

    Nixon, Brenda Chaumont

    This study evaluated the cognitive benefits and costs of incorporating biology-textbook and student-generated photographic images into the learning and assessment processes within a 10th grade biology classroom. The study implemented Wandersee's (2000) 20-Q Model of Image-Based Biology Test-Item Design (20-Q Model) to explore the use of photographic images to assess students' understanding of complex biological processes. A thorough review of the students' textbook using ScaleMaster R with PC Interface was also conducted. The photographs, diagrams, and other representations found in the textbook were measured to determine the percentage of each graphic depicted in the book and comparisons were made to the text. The theoretical framework that guided the research included Human Constructivist tenets espoused by Mintzes, Wandersee and Novak (2000). Physiological and cognitive factors of images and image-based learning as described by Robin (1992), Solso (1997) and Wandersee (2000) were examined. Qualitative case study design presented by Yin (1994), Denzin and Lincoln (1994) was applied and data were collected through interviews, observations, student activities, student and school artifacts and Scale Master IIRTM measurements. The results of the study indicate that although 24% of the high school biology textbook is devoted to photographic images which contribute significantly to textbook cost, the teacher and students paid little attention to photographic images other than as aesthetic elements for creating biological ambiance, wasting valuable opportunities for learning. The analysis of the photographs corroborated findings published by the Association American Association for the Advancement of Science that indicated "While most of the books are lavishly illustrated, these representations are rarely helpful, because they are too abstract, needlessly complicated, or inadequately explained" (Roseman, 2000, p. 2). The findings also indicate that applying the 20-Q

  10. DOSE ASSESSMENT OF THE FINAL INVENTORIES IN CENTER SLIT TRENCHES ONE THROUGH FIVE

    Energy Technology Data Exchange (ETDEWEB)

    Collard, L.; Hamm, L.; Smith, F.

    2011-05-02

    In response to a request from Solid Waste Management (SWM), this study evaluates the performance of waste disposed in Slit Trenches 1-5 by calculating exposure doses and concentrations. As of 8/19/2010, Slit Trenches 1-5 have been filled and are closed to future waste disposal in support of an ARRA-funded interim operational cover project. Slit Trenches 6 and 7 are currently in operation and are not addressed within this analysis. Their current inventory limits are based on the 2008 SA and are not being impacted by this study. This analysis considers the location and the timing of waste disposal in Slit Trenches 1-5 throughout their operational life. In addition, the following improvements to the modeling approach have been incorporated into this analysis: (1) Final waste inventories from WITS are used for the base case analysis where variance in the reported final disposal inventories is addressed through a sensitivity analysis; (2) Updated K{sub d} values are used; (3) Area percentages of non-crushable containers are used in the analysis to determine expected infiltration flows for cases that consider collapse of these containers; (4) An updated representation of ETF carbon column vessels disposed in SLIT3-Unit F is used. Preliminary analyses indicated a problem meeting the groundwater beta-gamma dose limit because of high H-3 and I-129 release from the ETF vessels. The updated model uses results from a recent structural analysis of the ETF vessels indicating that water does not penetrate the vessels for about 130 years and that the vessels remain structurally intact throughout the 1130-year period of assessment; and (5) Operational covers are included with revised installation dates and sets of Slit Trenches that have a common cover. With the exception of the modeling enhancements noted above, the analysis follows the same methodology used in the 2008 PA (WSRC, 2008) and the 2008 SA (Collard and Hamm, 2008). Infiltration flows through the vadose zone are

  11. Lake Granbury and Lake Whitney Assessment Initiative Final Scientific/Technical Report Summary

    Energy Technology Data Exchange (ETDEWEB)

    Harris, B. L. [Texas AgriLife Research, College Station, TX (United States); Roelke, Daniel [Texas AgriLife Research, College Station, TX (United States); Brooks, Bryan [Texas AgriLife Research, College Station, TX (United States); Grover, James [Texas AgriLife Research, College Station, TX (United States)

    2010-10-11

    A team of Texas AgriLife Research, Baylor University and University of Texas at Arlington researchers studied the biology and ecology of Prymnesium parvum (golden algae) in Texas lakes using a three-fold approach that involved system-wide monitoring, experimentation at the microcosm and mesocosm scales, and mathematical modeling. The following are conclusions, to date, regarding this organism's ecology and potential strategies for mitigation of blooms by this organism. In-lake monitoring revealed that golden algae are present throughout the year, even in lakes where blooms do not occur. Compilation of our field monitoring data with data collected by Texas Parks and Wildlife and Brazos River Authority (a period spanning a decade) revealed that inflow and salinity variables affect bloom formations. Thresholds for algae populations vary per lake, likely due to adaptations to local conditions, and also to variations in lake-basin morphometry, especially the presence of coves that may serve as hydraulic storage zones for P. parvum populations. More specifically, our in-lake monitoring showed that the highly toxic bloom that occurred in Lake Granbury in the winter of 2006/2007 was eliminated by increased river inflow events. The bloom was flushed from the system. The lower salinities that resulted contributed to golden algae not blooming in the following years. However, flushing is not an absolute requirement for bloom termination. Laboratory experiments have shown that growth of golden algae can occur at salinities ~1-2 psu but only when temperatures are also low. This helps to explain why blooms are possible during winter months in Texas lakes. Our in-lake experiments in Lake Whitney and Lake Waco, as well as our laboratory experiments, revealed that cyanobacteria, or some other bacteria capable of producing algicides, were able to prevent golden algae from blooming. Identification of this organism is a high priority as it may be a key to managing golden algae

  12. Assessment of students’ health condition by indicators of adaptation potential, biological age and bio-energetic reserves of organism

    Directory of Open Access Journals (Sweden)

    Martyniuk O.V.

    2015-06-01

    Full Text Available Purpose: to assess students’ health condition by indicators of adaptation potential, biological age and express-assessment. Material: in the research 47 first and second year girl students participated, who belonged to main health group. Results: we distributed the girl students into three groups: 14.89% of them were included in group with “safe” health condition; 34.04% - in group of “third state”; 51.06% were related to group with “ dangerous” health condition. We established that dangerous level was characterized by energy potential of below middle and low level. It is accompanied by accelerated processes of organism’s age destructions and tension of regulation mechanisms. Conclusions: the received results permit to further develop and generalize the data of students’ health’s assessment by indicators of adaptation potentials, biological age and physical health’s condition.

  13. Final Report - Assessment of Testing Options for the NTR at the INL

    Energy Technology Data Exchange (ETDEWEB)

    Howe, Steven D; McLing, Travis L; McCurry, Michael; Plummer, Mitchell A

    2013-02-01

    non-nuclear , sub-scale test using gas injection to validate the computational models; 4) Produce a preliminary cost estimate to build a nuclear furnace equivalent facility to test NTR fuel on a green field location on the INL site. The results show that the INL geology is substantially better suited to the SAFE testing method than the NTS site. The existence of impermeable interbeds just above the sub-surface aquifer ensure that no material from the test, radioactive or not, can enter the water table. Similar beds located just below the surface will prevent any gaseous products from reaching the surface for dispersion. The extremely high permeability of the strata between the interbeds allows rapid dispersion of the rocket exhaust. In addition, the high permeability suggests that a lower back-pressure may develop in the hole against the rocket thrust, which increases safety of operations. Finally, the cost of performing a sub-scale, non-nuclear verification experiment was determined to be $3M. The third method was assessed through discussions with INL staff resident at the site. In essence, any new Category I facility on any DOE site will cost in excess of $250M. Based on the results of this study, a cost estimate for testing a nuclear rocket at the INL site appears to be warranted. Given the fact that a new nuclear fuel may be possible that does not release any fission products, the SAFE testing option appears to be the most affordable.

  14. Cherry Valley National Wildlife Refuge Final Feasibility Study and Environmental Assessment

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In accordance with the National Environmental Policy Act (NEPA), as amended, the Service has developed a Final EA in response to the Cherry Valley National Wildlife...

  15. Final Programme and Abstracts. COST Action CM0603 Free Radicals in Chemical Biology (CHEMBIORADICAL) Joint Working Group

    International Nuclear Information System (INIS)

    The main objective of the Action is to promote a chemical biology approach for the investigation of free radical pathways. Chemical reactivity and molecular libraries are the start of a multidisciplinary research context 'from small molecules to large systems', culminating in the biological complexity. The Action aims at improving communication and exchange among neighbouring scientific fields, such as chemistry with several domains of life sciences, specifically addressing the real barrier consisting of specialist language and tools. Four working groups address the formation, reactivity and fate of free radicals involving bio-molecules, such as unsaturated lipids, aromatic-, cyclic- and sulphur-containing amino acid residues, sugar and base moieties of nucleic acids. Tasks concern the role of free radicals in normal cell metabolism and in damages, defining structural and functional modifications, in the framework of physiologically and pathologically related processes relevant to human quality of life and health. In the programme are involved 19 universities and research institutions from nearly all European countries. The research programme of the group has been carried and is still continued based on close bilateral collaboration with many foreign laboratories from Europe, USA (Notre Dame Radiation Laboratory) and Chile

  16. Final report on LDRD project: Semiconductor surface-emitting microcavity laser spectroscopy for analysis of biological cells and microstructures

    Energy Technology Data Exchange (ETDEWEB)

    Gourley, P.L.; McDonald, A.E. [Sandia National Labs., Albuquerque, NM (United States). Nanostructure and Semiconductor Physics Dept.; Gourley, M.F. [Washington Hospital Center, DC (United States); Bellum, J. [Coherent Technologies, Boulder, CO (United States)

    1997-08-01

    This article discusses a new intracavity laser technique that uses living or fixed cells as an integral part of the laser. The cells are placed on a GaAs based semiconductor wafer comprising one half of a vertical cavity surface-emitting laser. After placement, the cells are covered with a dielectric mirror to close the laser cavity. When photo-pumped with an external laser, this hybrid laser emits coherent light images and spectra that depend sensitively on the cell size, shape, and dielectric properties. The light spectra can be used to identify different cell types and distinguish normal and abnormal cells. The laser can be used to study single cells in real time as a cell-biology lab-on-a-chip, or to study large populations of cells by scanning the pump laser at high speed. The laser is well-suited to be integrated with other micro-optical or micro-fluidic components to lead to micro-optical-mechanical systems for analysis of fluids, particulates, and biological cells.

  17. Preliminary assessment of the interaction of introduced biological agents with biofilms in water distribution systems.

    Energy Technology Data Exchange (ETDEWEB)

    Sinclair, Michael B.; Caldwell, Sara; Jones, Howland D. T.; Altman, Susan Jeanne; Souza, Caroline Ann; McGrath, Lucas K.

    2005-12-01

    Basic research is needed to better understand the potential risk of dangerous biological agents that are unintentionally or intentionally introduced into a water distribution system. We report on our capabilities to conduct such studies and our preliminary investigations. In 2004, the Biofilms Laboratory was initiated for the purpose of conducting applied research related to biofilms with a focus on application, application testing and system-scale research. Capabilities within the laboratory are the ability to grow biofilms formed from known bacteria or biofilms from drinking water. Biofilms can be grown quickly in drip-flow reactors or under conditions more analogous to drinking-water distribution systems in annular reactors. Biofilms can be assessed through standard microbiological techniques (i .e, aerobic plate counts) or with various visualization techniques including epifluorescent and confocal laser scanning microscopy and confocal fluorescence hyperspectral imaging with multivariate analysis. We have demonstrated the ability to grow reproducible Pseudomonas fluorescens biofilms in the annular reactor with plate counts on the order of 10{sup 5} and 10{sup 6} CFU/cm{sup 2}. Stationary phase growth is typically reached 5 to 10 days after inoculation. We have also conducted a series of pathogen-introduction experiments, where we have observed that both polystyrene microspheres and Bacillus cereus (as a surrogate for B. anthracis) stay incorporated in the biofilms for the duration of our experiments, which lasted as long as 36 days. These results indicated that biofilms may act as a safe harbor for bio-pathogens in drinking water systems, making it difficult to decontaminate the systems.

  18. Chelating impact assessment of biological ad chemical chelates on metal extraction from contaminated soils

    International Nuclear Information System (INIS)

    Soil contamination is the result of uncontrolled waste dumping and poor practices by humans. Of all the pollutants heavy metals are of particular concern due to their atmospheric deposition, leaching capacity and non-biodegradability. Heavy metal containing effluent is discharged into the agricultural fields and water bodies. This results in the accumulation of heavy metals in soil and the crops grown on that soil. Studies have revealed detrimental impacts on soil fertility and the poor health of animals and humans. Phytoextraction is widely researched for remediation of heavy metal contaminated soil. To enhance the effect of phytoextraction heavy metals have to be available to the plants in soluble form. In this study the potential of different chelating agents was assessed in solubilizing the heavy metals making easy for plants to uptake them. For this purpose efficient chemical and biological chelating agent had to be identified. Along with that an optimum dose and application time for chemical chelating agent was determined. Ethylenediamine tetraacetic acid (EDTA), Diethylene triamine pentaacetic acid (DTPA), Nitriloacetic acid (NTA) were applied to the soil, containing Pb, Cr, Cu and Cd, at different concentrations and application time. Aspergillus niger and Aspergillus flavus were incubated in soil for different time periods. In correspondence with findings of the study, Pb and Cr were best solubilized by 5mM EDTA. For Cd and Cu 5mM DTPA carried out efficient chelation. NTA showed relatively inadequate solubilisation, although for Cr it performed equal to EDTA. A. niger and A. flavus instead of solubilizing adsorbed the metals in their biomass. Adsorption was mainly carried out by A. niger. (author)

  19. Win percentage: a novel measure for assessing the suitability of machine classifiers for biological problems

    Science.gov (United States)

    2012-01-01

    Background Selecting an appropriate classifier for a particular biological application poses a difficult problem for researchers and practitioners alike. In particular, choosing a classifier depends heavily on the features selected. For high-throughput biomedical datasets, feature selection is often a preprocessing step that gives an unfair advantage to the classifiers built with the same modeling assumptions. In this paper, we seek classifiers that are suitable to a particular problem independent of feature selection. We propose a novel measure, called "win percentage", for assessing the suitability of machine classifiers to a particular problem. We define win percentage as the probability a classifier will perform better than its peers on a finite random sample of feature sets, giving each classifier equal opportunity to find suitable features. Results First, we illustrate the difficulty in evaluating classifiers after feature selection. We show that several classifiers can each perform statistically significantly better than their peers given the right feature set among the top 0.001% of all feature sets. We illustrate the utility of win percentage using synthetic data, and evaluate six classifiers in analyzing eight microarray datasets representing three diseases: breast cancer, multiple myeloma, and neuroblastoma. After initially using all Gaussian gene-pairs, we show that precise estimates of win percentage (within 1%) can be achieved using a smaller random sample of all feature pairs. We show that for these data no single classifier can be considered the best without knowing the feature set. Instead, win percentage captures the non-zero probability that each classifier will outperform its peers based on an empirical estimate of performance. Conclusions Fundamentally, we illustrate that the selection of the most suitable classifier (i.e., one that is more likely to perform better than its peers) not only depends on the dataset and application but also on the

  20. Win percentage: a novel measure for assessing the suitability of machine classifiers for biological problems

    Directory of Open Access Journals (Sweden)

    Parry R Mitchell

    2012-03-01

    Full Text Available Abstract Background Selecting an appropriate classifier for a particular biological application poses a difficult problem for researchers and practitioners alike. In particular, choosing a classifier depends heavily on the features selected. For high-throughput biomedical datasets, feature selection is often a preprocessing step that gives an unfair advantage to the classifiers built with the same modeling assumptions. In this paper, we seek classifiers that are suitable to a particular problem independent of feature selection. We propose a novel measure, called "win percentage", for assessing the suitability of machine classifiers to a particular problem. We define win percentage as the probability a classifier will perform better than its peers on a finite random sample of feature sets, giving each classifier equal opportunity to find suitable features. Results First, we illustrate the difficulty in evaluating classifiers after feature selection. We show that several classifiers can each perform statistically significantly better than their peers given the right feature set among the top 0.001% of all feature sets. We illustrate the utility of win percentage using synthetic data, and evaluate six classifiers in analyzing eight microarray datasets representing three diseases: breast cancer, multiple myeloma, and neuroblastoma. After initially using all Gaussian gene-pairs, we show that precise estimates of win percentage (within 1% can be achieved using a smaller random sample of all feature pairs. We show that for these data no single classifier can be considered the best without knowing the feature set. Instead, win percentage captures the non-zero probability that each classifier will outperform its peers based on an empirical estimate of performance. Conclusions Fundamentally, we illustrate that the selection of the most suitable classifier (i.e., one that is more likely to perform better than its peers not only depends on the dataset and

  1. Risk assessment for produced water discharges to Louisiana open bays. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Meinhold, A.F.; DePhillips, M.P.; Holtzman, S.

    1996-03-22

    The US Department of Energy (USDOE) has a program of research in the environmental aspects of oil and gas extraction. This sampling project will characterize the environmental impacts associated with the discharge of naturally occurring radioactive materials (NORM), metals and organics in produced water. This report is part of a series of studies of the health and ecological risks from discharges of produced water to the Gulf of Mexico, supported by the USDOE. These assessments are being coordinated with the field study, using the collected data to perform human health and ecological risk assessments. These assessments will provide input to regulators in the development of guidelines and permits, and to industry in the development and use of appropriate discharge practices. The initial human health and ecological risk assessments consist of conservative screening analyses meant to identify potentially important contaminants, and to eliminate others from further consideration. More quantitative assessments were done for contaminants identified, in the screening analysis, as being of potential concern. Section 2 gives an overview of human health and ecological risk assessment to help put the analyses presented here in perspective. Section 3 provides the hazard assessment portion of the risk assessment, and identifies the important receptors and pathways of concern. Section 3 also outlines the approach taken to the risk assessments presented in the rest of the report. The remaining sections (4 through 9) present the human health and ecological risk assessments for discharges of produced water to open bays in Louisiana.

  2. Risk assessment for produced water discharges to Louisiana open bays. Final report

    International Nuclear Information System (INIS)

    The US Department of Energy (USDOE) has a program of research in the environmental aspects of oil and gas extraction. This sampling project will characterize the environmental impacts associated with the discharge of naturally occurring radioactive materials (NORM), metals and organics in produced water. This report is part of a series of studies of the health and ecological risks from discharges of produced water to the Gulf of Mexico, supported by the USDOE. These assessments are being coordinated with the field study, using the collected data to perform human health and ecological risk assessments. These assessments will provide input to regulators in the development of guidelines and permits, and to industry in the development and use of appropriate discharge practices. The initial human health and ecological risk assessments consist of conservative screening analyses meant to identify potentially important contaminants, and to eliminate others from further consideration. More quantitative assessments were done for contaminants identified, in the screening analysis, as being of potential concern. Section 2 gives an overview of human health and ecological risk assessment to help put the analyses presented here in perspective. Section 3 provides the hazard assessment portion of the risk assessment, and identifies the important receptors and pathways of concern. Section 3 also outlines the approach taken to the risk assessments presented in the rest of the report. The remaining sections (4 through 9) present the human health and ecological risk assessments for discharges of produced water to open bays in Louisiana

  3. Synthesis and biological incorporation of icons into macromolecules for NMR study. Final report, June 1, 1977--May 31, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Grant, D.M.; Horton, W.J.

    1978-05-31

    Carbon-13 enrichment synthesis and incorporation into three important biological systems have been carried out to provide materials for carbon-13 magnetic resonance studies. These systems include antibody-labeled haptens, labeled t-RNA and 5S-RNA molecules, and pyridoxal-5'-phosphate-labeled substrate mixtures. The synthesis phase of the work has been completed in all three cases, and the NMR studies completed on all but the antibody-hapten system which is still in process having been absorbed into other supported projects. Publications are now in preparation for the RNA and pyridoxal work. Preliminary results on the antibody-haptens work are encouraging as signals of antibody absorbed haptens have been observed but the results are still not yet conclusive.

  4. Review and assessments of potential environmental, health and safety impacts of MHD technology. Final draft

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    The purpose of this document is to develop an environmental, health and safety (EH and S) assessment and begin a site - specific assessment of these and socio - economic impacts for the magnetohydrodynamics program of the United States Department of Energy. This assessment includes detailed scientific and technical information on the specific EH and S issues mentioned in the MHD Environmental Development Plan. A review of current literature on impact-related subjects is also included. This document addresses the coal-fired, open-cycle MHD technology and reviews and assesses potential EH and S impacts resulting from operation of commercially-installed technology.

  5. 78 FR 110 - Supplemental Record of Decision; Final Supplementary Risk Assessment for the Boston University...

    Science.gov (United States)

    2013-01-02

    ... assessment, environmental justice, risk communications, biosafety, and infectious disease modeling. At... centrifuge aerosol release, an earthquake, and transportation accidents. To ensure examination...

  6. Assessing the Soil Physiological Potential Using Pedo-Biological Diagnosis Under Minimum-Tillage System and Mineral Fertilization

    Directory of Open Access Journals (Sweden)

    Lazar Bireescu

    2014-11-01

    Full Text Available The main objective of sustainable agriculture is the protection of environment and natural vegetal and soil resources. Accordingly, the objective of this research was to assess the impact of technological systems by minimum tillage on soil biological activity, using the Pedo-Biological Diagnosis of Soil Resources. Our research was conducted on haplic chernozem from Experimental Station of UASVM of Iasi, Romania, during the seasonal dynamic, to the soybean crop, on unfertilized and fertilized agrofond, using moderate mineral doses (N80P80 as average of 2009–2010 period, under minimum tillage (2x disk, paraplow, chisel compared to conventional (plugging at 20 cm and 30 cm. In the case of soil works with chisel and paraplow without return of furrow, the Pedo-Biological Diagnosis highlights an increase of soil physiological potential, in the both variants (unfertilized and fertilized, unlike the method of alternating the depth of plugging that proved to be ineffective.

  7. Biological Production of Methane from Lunar Mission Solid Waste: An Initial Feasibility Assessment

    Science.gov (United States)

    Strayer, Richard; Garland, Jay; Janine, Captain

    A preliminary assessment was made of the potential for biological production of methane from solid waste generated during an early planetary base mission to the moon. This analysis includes: 1) estimation of the amount of biodegradable solid waste generated, 2) background on the potential biodegradability of plastics given their significance in solid wastes, and 3) calculation of potential methane production from the estimate of biodegradable waste. The completed analysis will also include the feasibility of biological methane production costs associated with the biological processing of the solid waste. NASA workshops and Advanced Life Support documentation have estimated the projected amount of solid wastes generated for specific space missions. From one workshop, waste estimates were made for a 180 day transit mission to Mars. The amount of plastic packaging material was not specified, but our visual examination of trash returned from stocktickerSTS missions indicated a large percentage would be plastic film. This plastic, which is not biodegradable, would amount to 1.526 kgdw crew-1 d-1 or 6.10 kgdw d-1 for a crew of 4. Over a mission of 10 days this would amount to 61 kgdw of plastics and for an 180 day lunar surface habitation it would be nearly 1100 kgdw . Approx. 24 % of this waste estimate would be biodegradable (human fecal waste, food waste, and paper), but if plastic packaging was replaced with biodegradable plastic, then 91% would be biodegradable. Plastics are man-made long chain polymeric molecules, and can be divided into two main groups; thermoplastics and thermoset plastics. Thermoplastics comprise over 90% of total plastic use in the placecountry-regionUnited States and are derived from polymerization of olefins via breakage of the double bond and subsequent formation of additional carbon to carbon bonds. The resulting sole-carbon chain polymers are highly resistant to biodegradation and hydrolytic cleavage. Common thermoplastics include low

  8. Digital Resources in Instruction and Research: Assessing Faculty Discovery, Use and Needs--Final Summary Report

    Science.gov (United States)

    Tobias, Vicki

    2009-01-01

    In 2008, the Digital Initiatives Coordinating Committee (DICC) requested a comprehensive assessment of the UW Digital Collections (UWDC). The goal of this assessment was to better understand faculty awareness of and expectations for digital library resources, services and tools; obtain faculty feedback on digital resource and service needs that…

  9. BASINS 4.0 CLIMATE ASSESSMENT TOOL (CAT): SUPPORTING DOCUMENTATION AND USER'S MANUAL (FINAL REPORT)

    Science.gov (United States)

    The U.S. Environmental Protection Agency’s Global Change Research Program (GCRP) is an assessment-oriented program within the Office of Research and Development that focuses on assessing how potential changes in climate and other global environmental stressors may impact water qu...

  10. 76 FR 77019 - Final Adjusted Assessment of Annual Needs for the List I Chemicals: Ephedrine, Pseudoephedrine...

    Science.gov (United States)

    2011-12-09

    ... published in the Federal Register (76 FR 56807). That notice proposed to adjust the 2011 assessment of... calculation methodology previously described in the 2010 and 2011 assessment of annual needs (74 FR 60294 and 75 FR 79407 respectively). DEA considered changes in demand, changes in the national rate of...

  11. Ballast Water Risk Assessment, Ports of Mumbai and Jawaharlal Nehru, India, October 2003: Final Report

    Digital Repository Service at National Institute of Oceanography (India)

    Anil, A.C.; Clarke, C.; Hayes, T.; Hilliard, R.; Joshi, G.; Krishnamurthy, V.; Polglaze, J.; Sawant, S.S.; Raaymakers, S.

    , October 2003: Final Report vi Executive Summary The introduction of harmful aquatic organisms and pathogens to new environments via ships? ballast water (BW) and other vectors has been identified as one of the four greatest threats to the world?s oceans.................................................................................................................................................v Executive Summary ...................................................................................................................................vi 1 Introduction and Background...

  12. 76 FR 65717 - City of Broken Bow, OK; Notice of Availability of Final Environmental Assessment

    Science.gov (United States)

    2011-10-24

    ... Commission's (Commission or FERC) regulations, 18 CFR part 380 (Order No. 486, 52 FR 47897), the Office of Energy Projects has reviewed the application for an Original Major License for the Broken Bow Re... Energy Regulatory Commission City of Broken Bow, OK; Notice of Availability of Final...

  13. 77 FR 23741 - DEEPWATER HORIZON Oil Spill; Final Phase I Early Restoration Plan and Environmental Assessment

    Science.gov (United States)

    2012-04-20

    ... restoration process. Planning for additional early restoration actions is continuing. Neither the Phase I ERP... Fish and Wildlife Service DEEPWATER HORIZON Oil Spill; Final Phase I Early Restoration Plan and... natural resource trustee agencies (Trustees) have approved the Phase I Early Restoration Plan...

  14. The forgotten foot - an assessment of foot and ankle radiograph pathology in final year medical students.

    LENUS (Irish Health Repository)

    Groarke, P J

    2014-04-27

    It has been shown that doctors in Emergency Departments (EDs) have inconsistent knowledge of musculoskeletal anatomy. This is most likely due to a deficiency in focused musculoskeletal modules at undergraduate level in medical school. The aims of this study were to evaluate the knowledge of final year medical students on foot anatomy and common foot and ankle pathology as seen on radiographs.

  15. Biological regeneration of carrier material for the adsorption of halogen hydrocarbons in plants for cleaning up contaminated groundwater. Final report

    International Nuclear Information System (INIS)

    Halogen hydrocarbons and above all chlorinated hydrocarbons are widespread harmful substances in soils and in groundwater. When cleaning up groundwater contamination, the contaminants are brought into the gas phase by strip processes. From the gas phase, the contaminants can be adsorbed on different carrier materials, mostly active carbon. One was searching for ways to regenerate this adsorption material. The mixed culture from a sea sediment most suitable for the decomposition of chlorinated hydrocarbons was optimized regarding its decomposition performance and was later used on the technical scale. In the decomposition experiments on the large technical scale, the cultures were lodged on filling bodies which has a much higher amount of gaps. In this case, an optimum supply of the micro-organisms with oxygen and methane is guaranteed, which is used as co-substrate. No intermediate product was found in a gas chromatography examination. The biologically occupied stage is situated between a desorption column and the active carbon filters, and reduces the load of harmful substances which can no longer be brought into the gas phase by stripping out. This has the advantage that it can be integrated in existing plants and can be adapted to any case of contamination by lodging adapted micro-organisms on it. The basis for each application must be separately researched. (orig.)

  16. Purchase of a PhosphorImager System for plant biology research. Final progress report, July 1992--July 1994

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, A.O.

    1993-10-01

    Eight DOE supported plant biologists at the University of California-Berkeley were awarded funds ($163,000) for purchase of a Phosphorlmager System to improve the speed, sensitivity, resolution, and quantitation of radioactive data processing and analysis. These funds were used to purchase a Molecular Dynamics Phosphorlmager System consisting of the phosphorlmager, a densitometer, and high resolution storage phosphor screens that have extremely high trapping and storage capacity for energy emitted from isotopes used for biological research such as {sup 32}P, {sup 14}C, {sup 35}S, and {sup 125}I. Software provided with the package permits analysis of the data in several unique ways that are not currently feasible With other methods for analysis. The University of California has purchased additional computer hardware (A MacIntosh Quadra 800 Computer) and has upgraded an IBM computer Mod6l PS2-486 linked with on-line and on off-line workstations via ethernet systems for analysis of data. Data files can also be converted to a TIFF format suitable for graphic analysis and image production on the MacIntosh computer. The system is providing unique advantages for quantitation of data over extremely wide ranges of isotope levels and provides the ability to analyze and manipulate data over wide ranges of sensitivity not previously available with previously used methods of isotope quantitation.

  17. Feasibility studies of safety assessment methods for programmable automation systems. Final report of the AVV project

    International Nuclear Information System (INIS)

    Feasibility studies of two different groups of methodologies for safety assessment of programmable automation systems has been executed at the Technical Research Centre of Finland (VTT). The studies concerned the dynamic testing methods and the fault tree (FT) and failure mode and effects analysis (FMEA) methods. In order to get real experience in the application of these methods, an experimental testing of two realistic pilot systems were executed and a FT/FMEA analysis of a programmable safety function accomplished. The purpose of the studies was not to assess the object systems, but to get experience in the application of methods and assess their potentials and development needs. (46 refs., 21 figs.)

  18. Protocols for assessing radiofrequency interactions with gold nanoparticles and biological systems for non-invasive hyperthermia cancer therapy.

    Science.gov (United States)

    Corr, Stuart J; Cisneros, Brandon T; Green, Leila; Raoof, Mustafa; Curley, Steven A

    2013-08-28

    Cancer therapies which are less toxic and invasive than their existing counterparts are highly desirable. The use of RF electric-fields that penetrate deep into the body, causing minimal toxicity, are currently being studied as a viable means of non-invasive cancer therapy. It is envisioned that the interactions of RF energy with internalized nanoparticles (NPs) can liberate heat which can then cause overheating (hyperthermia) of the cell, ultimately ending in cell necrosis. In the case of non-biological systems, we present detailed protocols relating to quantifying the heat liberated by highly-concentrated NP colloids. For biological systems, in the case of in vitro experiments, we describe the techniques and conditions which must be adhered to in order to effectively expose cancer cells to RF energy without bulk media heating artifacts significantly obscuring the data. Finally, we give a detailed methodology for in vivo mouse models with ectopic hepatic cancer tumors.

  19. West Texas geothermal resource assessment. Part II. Preliminary utilization assessment of the Trans-Pecos geothermal resource. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Gilliland, M.W.; Fenner, L.B.

    1980-01-01

    The utilization potential of geothermal resources in Trans-Pecos, Texas was assessed. The potential for both direct use and electric power generation were examined. As with the resource assessment work, the focus was on the Hueco Tanks area in northeastern El Paso County and the Presidio Bolson area in Presidio County. Suitable users of the Hueco Tanks and Presidio Bolson resource areas were identified by matching postulated temperature characteristics of the geothermal resource to the need characteristics of existing users in each resource area. The amount of geothermal energy required and the amount of fossil fuel that geothermal energy would replace were calculated for each of the users identified as suitable. Current data indicate that temperatures in the Hueco Tanks resource area are not high enough for electric power generation, but in at least part of the Presidio Bolson resource area, they may be high enough for electric power generation.

  20. SYMBIOSIS: development, implementation, and assessment of a model curriculum across biology and mathematics at the introductory level.

    Science.gov (United States)

    Depelteau, Audrey M; Joplin, Karl H; Govett, Aimee; Miller, Hugh A; Seier, Edith

    2010-01-01

    "It takes a lot of courage to release the familiar and seemingly secure, to embrace the new. But there is no real security in what is no longer meaningful. There is more security in the adventurous and exciting, for in movement there is life, and in change there is power." Alan Cohen (Used by permission. All rights reserved. For more information on Alan Cohen's books and programs, see (www.alancohen.com.) With the support of the East Tennessee State University (ETSU) administration and a grant from Howard Hughes Medical Institute, the departments of Biological Sciences, Mathematics and Statistics, and Curriculum and Instruction have developed a biology-math integrated curriculum. An interdisciplinary faculty team, charged with teaching the 18 curriculum modules, designed this three-semester curriculum, known as SYMBIOSIS. This curriculum was piloted to two student cohorts during the developmental stage. The positive feedback and assessment results of this project have given us the foundation to implement the SYMBIOSIS curriculum as a replacement for the standard biology majors curriculum at the introductory level. This article addresses the history and development of the curriculum, previous assessment results and current assessment protocol, and the future of ETSU's approach to implementing the SYMBIOSIS curriculum. PMID:20810967

  1. San Francisco Bay National Wildlife Refuge Predator Management Plan and Final Environmental Assessment

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The U.S. Fish and Wildlife Service has prepared an environmental assessment to evaluate the effects associated with the implementation of a predator management...

  2. Final Amendment to the Comprehensive Conservation Plan & Environmental Assessment: Flint Hills National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is an amendment, accompanied by an Environmental Assessment (EA), to the current 2000 Comprehensive Conservation Plan (CCP) for Flint Hills NWR. The purpose of...

  3. Final Environmental Assessment Hunt Program Proposal Ohio River Islands National Wildlife Refuge 1994

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this environmental assessment is to address the impacts of opening the Ohio River Islands National Wildlife Refuge to hunting. The ultimate purpose...

  4. 76 FR 41323 - Notice of Availability of the Final Environmental Assessment for the Metropolitan Branch Trail

    Science.gov (United States)

    2011-07-13

    ... Environmental Assessment for the Metropolitan Branch Trail (MBT) Project. SUMMARY: The U.S. Federal Highway... resulting from constructing and operating the MBT on sections of land owned by the NPS within the area...

  5. Assessment of the potentially beneficial uses of krypton-85. Final report, Task 64

    International Nuclear Information System (INIS)

    Results of a study aimed at assessing the potentially beneficial uses of 85Kr indicate that self-luminous light sources appear to be the foremost benefical use of 85Kr. Other assessed uses include heat sources for thermoelectric generators, heat sources for environmental control of submersibles, heat sources for thermodynamic energy cycles, polymerization processes, nondestructive testing, leak detection, biomedical applications, and liquid waste treatment. (TFD)

  6. Integrity assessment plan for PNL 300 area radioactive hazardous waste tank system. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The Pacific Northwest Laboratory (PNL), operated by Battelle Memorial Institute under contract to the U.S. Department of Energy, operates tank systems for the U.S. Department of Energy, Richland Operations Office (DOE-RL), that contain dangerous waste constituents as defined by Washington State Department of Ecology (WDOE) Dangerous Waste Regulations, Washington Administrative Code (WAC) 173-303-040(18). Chapter 173-303-640(2) of the WAC requires the performance of integrity assessments for each existing tank system that treats or stores dangerous waste, except those operating under interim status with compliant secondary containment. This Integrity Assessment Plan (IAP) identifies all tasks that will be performed during the integrity assessment of the PNL-operated Radioactive Liquid Waste Systems (RLWS) associated with the 324 and 325 Buildings located in the 300 Area of the Hanford Site. It describes the inspections, tests, and analyses required to assess the integrity of the PNL RLWS (tanks, ancillary equipment, and secondary containment) and provides sufficient information for adequate budgeting and control of the assessment program. It also provides necessary information to permit the Independent, Qualified, Registered Professional Engineer (IQRPE) to approve the integrity assessment program.

  7. Integrity assessment plan for PNL 300 area radioactive hazardous waste tank system. Final report

    International Nuclear Information System (INIS)

    The Pacific Northwest Laboratory (PNL), operated by Battelle Memorial Institute under contract to the U.S. Department of Energy, operates tank systems for the U.S. Department of Energy, Richland Operations Office (DOE-RL), that contain dangerous waste constituents as defined by Washington State Department of Ecology (WDOE) Dangerous Waste Regulations, Washington Administrative Code (WAC) 173-303-040(18). Chapter 173-303-640(2) of the WAC requires the performance of integrity assessments for each existing tank system that treats or stores dangerous waste, except those operating under interim status with compliant secondary containment. This Integrity Assessment Plan (IAP) identifies all tasks that will be performed during the integrity assessment of the PNL-operated Radioactive Liquid Waste Systems (RLWS) associated with the 324 and 325 Buildings located in the 300 Area of the Hanford Site. It describes the inspections, tests, and analyses required to assess the integrity of the PNL RLWS (tanks, ancillary equipment, and secondary containment) and provides sufficient information for adequate budgeting and control of the assessment program. It also provides necessary information to permit the Independent, Qualified, Registered Professional Engineer (IQRPE) to approve the integrity assessment program

  8. Assessment of control technology for stationary sources. Volume II: control technology data tables. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Minicucci, D.; Herther, M.; Babb, L.; Kuby, W.

    1980-02-01

    This report, the Control Technology Data Tables, is the second volume of the three-volume final report for the contract. It presents in tabular format, qualitative descriptions of control options for the various sources and quantitative information on control technology cost, efficiency, reliability, energy consumption, other environmental impacts and application status. Also included is a code list which classifies the stationary sources examined by industry, process, and emission source.

  9. Development of biological and chemical methods for environmental monitoring of DOE waste disposal and storage facilities. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1989-04-01

    Hazardous chemicals in the environment have received ever increasing attention in recent years. In response to ongoing problems with hazardous waste management, Congress enacted the Resource Conservation and Recovery Act (RCRA) in 1976. In 1980, Congress adopted the Comprehensive Environmental Response Compensation, and Liability Act (CERCLA), commonly called Superfund to provide for emergency spill response and to clean up closed or inactive hazardous waste sites. Scientists and engineers have begun to respond to the hazardous waste challenge with research and development on treatment of waste streams as well as cleanup of polluted areas. The magnitude of the problem is just now beginning to be understood. The U.S. Environmental Protection Agency (USEPA) National Priorities List as of September 13 1985, contained 318 proposed sites and 541 final sites (USEPA, 1985). Estimates of up to 30,000 sites containing hazardous wastes (1,200 to 2,000 of which present a serious threat to public health) have been made (Public Law 96-150). In addition to the large number of sites, the costs of cleanup using available technology are phenomenal. For example, a 10-acre toxic waste site in Ohio is to be cleaned up by removing chemicals from the site and treating the contaminated groundwater. The federal government has already spent more than $7 million to remove the most hazardous wastes and the groundwater decontamination alone is expected to take at least 10 years and cost $12 million. Another example of cleanup costs comes from the State of California Commission for Economic Development which predicts a bright economic future for the state except for the potential outlay of $40 billion for hazardous waste cleanup mandated by federal and state laws.

  10. A biological/chemical process for reduced waste and energy consumption, Caprolactam production: Phase 1, Select microorganisms and demonstrate feasibility. Final report

    Energy Technology Data Exchange (ETDEWEB)

    St.Martin, E.J.

    1995-08-01

    A novel biological/chemical process for converting cyclohexane into caprolactam was investigated. Microorganisms in a bioreactor would be used to convert cyclohexane into caprolactone followed by chemical synthesis of caprolactam using ammonia. The proposed bioprocess would be more energy efficient and reduce byproducts and wastes that are generated by the current chemical process. We have been successful in isolating from natural soil and water samples two microorganisms that can utilize cyclohexane as a sole source of carbon and energy for growth. These microorganisms were shown to have the correct metabolic intermediates and enzymes to convert cyclohexane into cyclohexanol, cyclohexanone and caprolactone. Genetic techniques to create and select for caprolactone hydrolase negative-mutants are being developed. These blocked-mutants will be used to convert cyclohexane into caprolactone but, because of the block, be unable to metabolize the caprolactone further and excrete it as a final end product.

  11. Examining Portfolio-Based Assessment in an Upper-Level Biology Course

    Science.gov (United States)

    Ziegler, Brittany Ann

    2012-01-01

    Historically, students have been viewed as empty vessels and passive participants in the learning process but students actually are active forming their own conceptions. One way student learning is impacted is through assessment. Alternative assessment, which contrasts traditional assessment methods, takes into account how students learn by…

  12. A Comparison of Two Low-Stakes Methods for Administering a Program-Level Biology Concept Assessment

    Directory of Open Access Journals (Sweden)

    Brian A. Couch

    2015-09-01

    Full Text Available Concept assessments are used commonly in undergraduate science courses to assess student learning and diagnose areas of student difficulty. While most concept assessments align with the content of individual courses or course topics, some concept assessments have been developed for use at the programmatic level to gauge student progress and achievement over a series of courses or an entire major. The broad scope of a program-level assessment, which exceeds the content of any single course, creates several test administration issues, including finding a suitable time for students to take the assessment and adequately incentivizing student participation. These logistical considerations must also be weighed against test security and the ability of students to use unauthorized resources that could compromise test validity. To understand how potential administration methods affect student outcomes, we administered the Molecular Biology Capstone Assessment (MBCA to three pairs of matched upper-division courses in two ways: an online assessment taken by students outside of class and a paper-based assessment taken during class. We found that overall test scores were not significantly different and that individual item difficulties were highly correlated between these two administration methods. However, in-class administration resulted in reduced completion rates of items at the end of the assessment. Taken together, these results suggest that an online, outside-of-class administration produces scores that are comparable to a paper-based, in-class format and has the added advantages that instructors do not have to dedicate class time and students are more likely to complete the entire assessment.

  13. A Comparison of Two Low-Stakes Methods for Administering a Program-Level Biology Concept Assessment.

    Science.gov (United States)

    Couch, Brian A; Knight, Jennifer K

    2015-12-01

    Concept assessments are used commonly in undergraduate science courses to assess student learning and diagnose areas of student difficulty. While most concept assessments align with the content of individual courses or course topics, some concept assessments have been developed for use at the programmatic level to gauge student progress and achievement over a series of courses or an entire major. The broad scope of a program-level assessment, which exceeds the content of any single course, creates several test administration issues, including finding a suitable time for students to take the assessment and adequately incentivizing student participation. These logistical considerations must also be weighed against test security and the ability of students to use unauthorized resources that could compromise test validity. To understand how potential administration methods affect student outcomes, we administered the Molecular Biology Capstone Assessment (MBCA) to three pairs of matched upper-division courses in two ways: an online assessment taken by students outside of class and a paper-based assessment taken during class. We found that overall test scores were not significantly different and that individual item difficulties were highly correlated between these two administration methods. However, in-class administration resulted in reduced completion rates of items at the end of the assessment. Taken together, these results suggest that an online, outside-of-class administration produces scores that are comparable to a paper-based, in-class format and has the added advantages that instructors do not have to dedicate class time and students are more likely to complete the entire assessment.

  14. Development of biological indices for identifying and evaluating impacts of pollutants on freshwater ecosystems. Final report, June 1975-October 1980

    Energy Technology Data Exchange (ETDEWEB)

    Cairns, J. Jr.; Cherry, D.S.

    1980-09-30

    The ten Research Areas reported included: (1) the development of functional indices for identifying and evaluating impacts of pollutants on Aufwuchs communities, (2) relationship of protozoan colonization rates to the eutrophication process, (3) testing of methods to determine the functioning of zooplankton communities subjected to entrainment stress, (4) the use of the first steps of detritus processing (microbial decomposition) as a technique for assessing pollutional stress on aquatic communities in a river system, (5) relationship of protozoan invasion and extinction rate to the eutrophication process, (6) extension of present early colonization studies to the simultaneous evaluation of natural environmental parameters and power plant effluents and application of the early colonization approach to microbial communities in streams of the New River drainage, (7) testing of single species-community responses of protozoans from selected heavy metals, (8) the effects of selected power plant pollutants on grazer utilization of Aufwuchs, (9) investigation of bioconcentration and bioaccumulation mechanisms of the Asiatic clam (Corbicula fluminea) populations in field artificial streams and laboratory microcosms with reference to physical chemistry and diet alterations, and (10) investigation of the homeostatic regulation in bluegill sunfish following acute hypothermal shock and to other power plant related effluents.

  15. Geothermal resource assessment of the Yucca Mountain Area, Nye County, Nevada. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Flynn, T.; Buchanan, P.; Trexler, D. [Nevada Univ., Las Vegas, NV (United States). Harry Reid Center for Environmental Studies, Division of Earth Sciences; Shevenell, L., Garside, L. [Nevada Univ., Reno, NV (United States). Mackay School of Mines, Nevada Bureau of Mines and Geology

    1995-12-01

    An assessment of the geothermal resources within a fifty-mile radius of the Yucca Mountain Project area was conducted to determine the potential for commercial development. The assessment includes collection, evaluation, and quantification of existing geological, geochemical, hydrological, and geophysical data within the Yucca Mountain area as they pertain to geothermal phenomena. Selected geologic, geochemical, and geophysical data were reduced to a set of common-scale digital maps using Geographic Information Systems (GIS) for systematic analysis and evaluation. Available data from the Yucca Mountain area were compared to similar data from developed and undeveloped geothermal areas in other parts of the Great Basin to assess the resource potential for future geothermal development at Yucca Mountain. This information will be used in the Yucca Mountain Site Characterization Project to determine the potential suitability of the site as a permanent underground repository for high-level nuclear waste.

  16. Final report of the safety assessment of allantoin and its related complexes.

    Science.gov (United States)

    Becker, Lillian C; Bergfeld, Wilma F; Belsito, Donald V; Klaassen, Curtis D; Marks, James G; Shank, Ronald C; Slaga, Thomas J; Snyder, Paul W; Alan Andersen, F

    2010-05-01

    Allantoin is a heterocyclic organic compound. Allantoin ascorbate, allantoin biotin, allantoin galacturonic acid, allantoin glycyrrhetinic acid, allantoin panthenol, and allantoin polygalacturonic acid are complexes of allantoin. All of the ingredients in this review act as skin-conditioning agents. Allantoin was reported to be used in 1376 cosmetic products at concentrations up to 2%. There are data gaps regarding use and concentration of the remaining allantoin complexes. Ascorbic acid, biotin, glycyrrhetinic acid, and panthenol have been determined by the CIR Expert Panel to be safe. Galacturonic acid and polygalacturonic acid have not been reviewed by the CIR Expert Panel, and substantial data on these chemicals were not available. The safety test data in this safety assessment and in previous safety assessments were considered sufficient to support the safety of allantoin and the allantoin complexes in product categories and at concentrations reviewed in this safety assessment. PMID:20448269

  17. Environmentally based siting assessment for synthetic-liquid-fuels facilities. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    A detailed assessment of the major environmental constraints to siting a synthetic fuels industry and the results of that assessment are used to determine on a regional basis the potential for development of such an industry with minimal environmental conflicts. Secondly, the ability to mitigate some of the constraining impacts through alternative institutional arrangements, especially in areas that are judged to have a low development potential is also assessed. Limitations of the study are delineated, but specifically, the study is limited geographically to well-defined boundaries that include the prime coal and oil shale resource areas. The critical factors used in developing the framework are air quality, water availability, socioeconomic capacity, ecological sensitivity, environmental health, and the management of Federally owned lands. (MCW)

  18. Geothermal resource assessment of the Yucca Mountain Area, Nye County, Nevada. Final report

    International Nuclear Information System (INIS)

    An assessment of the geothermal resources within a fifty-mile radius of the Yucca Mountain Project area was conducted to determine the potential for commercial development. The assessment includes collection, evaluation, and quantification of existing geological, geochemical, hydrological, and geophysical data within the Yucca Mountain area as they pertain to geothermal phenomena. Selected geologic, geochemical, and geophysical data were reduced to a set of common-scale digital maps using Geographic Information Systems (GIS) for systematic analysis and evaluation. Available data from the Yucca Mountain area were compared to similar data from developed and undeveloped geothermal areas in other parts of the Great Basin to assess the resource potential for future geothermal development at Yucca Mountain. This information will be used in the Yucca Mountain Site Characterization Project to determine the potential suitability of the site as a permanent underground repository for high-level nuclear waste

  19. A "weight of evidence" approach for the integration of environmental "triad" data to assess ecological risk and biological vulnerability.

    Science.gov (United States)

    Dagnino, Alessandro; Sforzini, Susanna; Dondero, Francesco; Fenoglio, Stefano; Bona, Elisa; Jensen, John; Viarengo, Aldo

    2008-07-01

    A new Expert Decision Support System (EDSS) that can integrate Triad data for assessing environmental risk and biological vulnerability at contaminated sites has been developed. Starting with ecosystem relevance, the EDSS assigns different weights to the results obtained from Triad disciplines. The following parameters have been employed: 1) chemical soil analyses (revealing the presence of potentially dangerous substances), 2) ecotoxicological bioassays (utilizing classical endpoints such as survival and reproduction rates), 3) biomarkers (showing sublethal pollutant effects), and 4) ecological parameters (assessing changes in community structure and functions). For each Triad discipline, the EDSS compares the data obtained at the studied field sites with reference values and calculates different 0-1 indexes (e.g., Chemical Risk Index, Ecotoxicological Risk Index, and Ecological Risk Index). The EDSS output consists of 3 indexes: 1) Environmental Risk index (EnvRI), quantifying the levels of biological damage at population-community level, 2) Biological Vulnerability Index (BVI), assessing the potential threats to biological equilibriums, and 3) Genotoxicity Index (GTI), screening genotoxicity effects. The EDSS has been applied in the integration of a battery of Triad data obtained during the European Union-funded Life Intervention in the Fraschetta Area (LINFA) project, which has been carried out in order to estimate the potential risk from soils of a highly anthropized area (Alessandria, Italy) mainly impacted by deposition of atmospheric pollutants. Results obtained during 4 seasonal sampling campaigns (2004-2005) show maximum values of EnvRI in sites A and B (characterized by industrial releases) and lower levels in site D (affected by vehicular traffic emissions). All 3 potentially polluted sites have shown high levels of BVI and GTI, suggesting a general change from reference conditions (site C). PMID:18393577

  20. A "weight of evidence" approach for the integration of environmental "triad" data to assess ecological risk and biological vulnerability.

    Science.gov (United States)

    Dagnino, Alessandro; Sforzini, Susanna; Dondero, Francesco; Fenoglio, Stefano; Bona, Elisa; Jensen, John; Viarengo, Aldo

    2008-07-01

    A new Expert Decision Support System (EDSS) that can integrate Triad data for assessing environmental risk and biological vulnerability at contaminated sites has been developed. Starting with ecosystem relevance, the EDSS assigns different weights to the results obtained from Triad disciplines. The following parameters have been employed: 1) chemical soil analyses (revealing the presence of potentially dangerous substances), 2) ecotoxicological bioassays (utilizing classical endpoints such as survival and reproduction rates), 3) biomarkers (showing sublethal pollutant effects), and 4) ecological parameters (assessing changes in community structure and functions). For each Triad discipline, the EDSS compares the data obtained at the studied field sites with reference values and calculates different 0-1 indexes (e.g., Chemical Risk Index, Ecotoxicological Risk Index, and Ecological Risk Index). The EDSS output consists of 3 indexes: 1) Environmental Risk index (EnvRI), quantifying the levels of biological damage at population-community level, 2) Biological Vulnerability Index (BVI), assessing the potential threats to biological equilibriums, and 3) Genotoxicity Index (GTI), screening genotoxicity effects. The EDSS has been applied in the integration of a battery of Triad data obtained during the European Union-funded Life Intervention in the Fraschetta Area (LINFA) project, which has been carried out in order to estimate the potential risk from soils of a highly anthropized area (Alessandria, Italy) mainly impacted by deposition of atmospheric pollutants. Results obtained during 4 seasonal sampling campaigns (2004-2005) show maximum values of EnvRI in sites A and B (characterized by industrial releases) and lower levels in site D (affected by vehicular traffic emissions). All 3 potentially polluted sites have shown high levels of BVI and GTI, suggesting a general change from reference conditions (site C).

  1. Direct heat applications of geothermal energy in The Geysers/Clear Lake region. Volume I. Geotechnical assessment, agribusiness applications, socioeconomic assessment, engineering assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1977-08-01

    The different uses to which geothermal heat and fluids could be applied as a direct utilization of resource or as heat utilization are explored. The following aspects are covered: geotechnical assessment, agricultural and industrial applications, socioeconomic assessment, and engineering assessment. (MHR)

  2. Market Assessment for Capturing Water Conservation Opportunities in the Federal Sector; FINAL

    International Nuclear Information System (INIS)

    The Department of Energy's Federal Energy Management Program (FEMP) is considering the development of a technology-specific Super-Energy Saving Performance Contract (ESPC) for water conservation. Prior to the development however, FEMP requires the completion of a market assessment to better understand the water conservation opportunities and the strategies available for capturing them. Thus, this market assessment has been undertaken to evaluate the water conservation opportunities and answer the key questions necessary for FEMP to make recommendations on whether or not to proceed with strategies for water conservation primarily through the development of a water conservation technology-specific performance contract

  3. Hydrogen/halogen energy storage system: safety, performance, and cost assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Spaziante, P.M.; Sioli, G.C.; Trotta, R.

    1979-02-01

    The aim of this work was to make realistic assessments of the safety, performance, and installation costs of an electrochemically regenerative H/sub 2//Cl/sub 2/ energy storage system based on detailed engineering designs of plant configurations. Extensive laboratory tests in FY 1976, 1977, and 1978 provided the needed theoretical and experimental data for this study. The effectiveness of this scheme of energy storage required practical confirmation. In this assessment particular care was taken to list and include all the secondary units needed for plant operation. Results are detailed. (WHK)

  4. Cost Quality Management Assessment for the Idaho Operations Office. Final report

    International Nuclear Information System (INIS)

    The Office of Engineering and Cost Management (EM-24) conducted a Cost Quality Management Assessment of EM-30 and EM-40 activities at the Idaho National Engineering Laboratory on Feb. 3--19, 1992 (Round I). The CQMA team assessed the cost and cost-related management activities at INEL. The Round II CQMA, conducted at INEL Sept. 19--29, 1994, reviewed EM-30, EM-40, EM-50, and EM-60 cost and cost-related management practices against performance objectives and criteria. Round II did not address indirect cost analysis. INEL has made measurable progress since Round I

  5. Cost Quality Management Assessment for the Idaho Operations Office. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Office of Engineering and Cost Management (EM-24) conducted a Cost Quality Management Assessment of EM-30 and EM-40 activities at the Idaho National Engineering Laboratory on Feb. 3--19, 1992 (Round I). The CQMA team assessed the cost and cost-related management activities at INEL. The Round II CQMA, conducted at INEL Sept. 19--29, 1994, reviewed EM-30, EM-40, EM-50, and EM-60 cost and cost-related management practices against performance objectives and criteria. Round II did not address indirect cost analysis. INEL has made measurable progress since Round I.

  6. 78 FR 31343 - Final Priorities, Requirement, Definitions, and Selection Criteria-Enhanced Assessment Instruments

    Science.gov (United States)

    2013-05-23

    ... program requirements. While we understand the value of tools to improve teaching and learning, in light of... Learning Outcomes and the Center on Standards and Assessments Implementation, to provide technical... of Education and HHS have worked closely together over the last four years on the Early...

  7. 77 FR 49457 - Availability of the Final Environmental Assessment and Finding of No Significant Impact for...

    Science.gov (United States)

    2012-08-16

    ... Assessment and Finding of No Significant Impact for Non-native Plant Control and Re-establishment of Riparian... Management Lands are available. A notice of finding of no significant impact dated January 24, 2012, provided..., wetlands, wild and scenic rivers, or ecologically critical areas. The proposed action will impact...

  8. Risk Informed Assessment of Regulatory and Design Requirements for Future Nuclear Power Plants - Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Ritterbusch, Stanley; Golay, Michael; Duran, Felicia; Galyean, William; Gupta, Abhinav; Dimitrijevic, Vesna; Malsch, Marty

    2003-01-29

    OAK B188 Summary of methods proposed for risk informing the design and regulation of future nuclear power plants. All elements of the historical design and regulation process are preserved, but the methods proposed for new plants use probabilistic risk assessment methods as the primary decision making tool.

  9. Preliminary Assessment/Investigation Final Summary Report: "Dead Zone" Site, Laysan Island, Hawaiian Island NWR Complex

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this report is to assess the risks that the "Laysan Dead Zone" poses to the health of U.S. Fish and Wildlife Service (Service) personnel and natural...

  10. 77 FR 55503 - Final Adjusted Assessment of Annual Needs for the List I Chemicals Ephedrine, Pseudoephedrine...

    Science.gov (United States)

    2012-09-10

    ... Phenylpropanolamine for 2012'' was published in the Federal Register (77 FR 42333). That notice proposed to adjust the... annual needs (74 FR 60294 and 75 FR 79407 respectively). DEA considered changes in demand, changes in the... determining the proposed 2012 assessment of annual needs, as published on September 14, 2011, at 76 FR...

  11. Final Pantex Report - 2006 [Phase 1 plan for assessment of Former Workers at the Pantex Facility

    International Nuclear Information System (INIS)

    The purpose of this project was to develop a Phase 1 plan for assessment of Former Workers at the Pantex Facility in Amarillo, TX and to determine the suitability to start a medical surveillance program among former workers for this site

  12. Final Pantex Report - 2006 [Phase 1 plan for assessment of Former Workers at the Pantex Facility

    Energy Technology Data Exchange (ETDEWEB)

    Abdo, Ronna

    2013-07-18

    The purpose of this project was to develop a Phase 1 plan for assessment of Former Workers at the Pantex Facility in Amarillo, TX and to determine the suitability to start a medical surveillance program among former workers for this site.

  13. Effect of Video Triggering During Conventional Lectures on Final Grades of Dental Students in an Oral Biology Course: A Two-Year Retrospective Study.

    Science.gov (United States)

    Farooq, Imran; Al-Jandan, Badr A

    2015-12-01

    The aim of this study was to analyze the effect of the inclusion of video triggers in conventional face-to-face lectures on the final grades of dental students in an oral biology course. The study consisted of two groups of students taking the course in two academic years at a dental school in Saudi Arabia: group 1, 2013-14 (control); and group 2, 2014-15. The total sample comprised 163 students (n=163; group 1: 71 and group 2: 92). Group 1 received lectures without any videos, whereas group 2 received lectures that included two to three videos of one to five minutes in duration with triggering effect (a video was shown every 10-15 minutes into the lecture). The final examination grades of the students were accessed retrospectively, and the data were compared with a chi-square test. The results confirmed that a higher number of students who received video triggering during lectures (group 2) performed better than their counterparts who did not receive video triggers (group 1); the difference was statistically significant (p<0.05). Among the group 2 students, 26% achieved a grade of A, and 37% achieved a grade of B. In contrast, only 7% of the group 1 students obtained a grade of A, and 31% achieved a grade of B. These results suggest that video triggers may offer an advantage over conventional methods and their inclusion in lectures can be a way to enhance students' learning.

  14. Requirements for Foreign and Domestic Establishment Registration and Listing for Human Drugs, Including Drugs That Are Regulated Under a Biologics License Application, and Animal Drugs. Final rule.

    Science.gov (United States)

    2016-08-31

    The Food and Drug Administration (FDA) is amending its regulations governing drug establishment registration and drug listing. These amendments reorganize, modify, and clarify current regulations concerning who must register establishments and list human drugs, human drugs that are also biological products, and animal drugs. The final rule requires electronic submission, unless waived in certain circumstances, of registration and listing information. This rulemaking pertains to finished drug products and to active pharmaceutical ingredients (APIs) alone or together with one or more other ingredients. The final rule describes how and when owners or operators of establishments at which drugs are manufactured or processed must register their establishments with FDA and list the drugs they manufacture or process. In addition, the rule makes certain changes to the National Drug Code (NDC) system. We are taking this action to improve management of drug establishment registration and drug listing requirements and make these processes more efficient and effective for industry and for us. This action also supports implementation of the electronic prescribing provisions of the Medicare Prescription Drug, Improvement, and Modernization Act of 2003 (MMA) and the availability of current drug labeling information through DailyMed, a computerized repository of drug information maintained by the National Library of Medicine. PMID:27580511

  15. Assessment of the effects of student response systems on student learning and attitudes over a broad range of biology courses.

    Science.gov (United States)

    Preszler, Ralph W; Dawe, Angus; Shuster, Charles B; Shuster, Michèle

    2007-01-01

    With the advent of wireless technology, new tools are available that are intended to enhance students' learning and attitudes. To assess the effectiveness of wireless student response systems in the biology curriculum at New Mexico State University, a combined study of student attitudes and performance was undertaken. A survey of students in six biology courses showed that strong majorities of students had favorable overall impressions of the use of student response systems and also thought that the technology improved their interest in the course, attendance, and understanding of course content. Students in lower-division courses had more strongly positive overall impressions than did students in upper-division courses. To assess the effects of the response systems on student learning, the number of in-class questions was varied within each course throughout the semester. Students' performance was compared on exam questions derived from lectures with low, medium, or high numbers of in-class questions. Increased use of the response systems in lecture had a positive influence on students' performance on exam questions across all six biology courses. Students not only have favorable opinions about the use of student response systems, increased use of these systems increases student learning. PMID:17339392

  16. Assessment of Blood Contamination in Biological Fluids Using MALDI-TOF MS.

    Science.gov (United States)

    Laks, Katrina; Kirsipuu, Tiina; Dmitrijeva, Tuuli; Salumets, Andres; Palumaa, Peep

    2016-06-01

    Biological fluid sample collection often includes the risk of blood contamination that may alter the proteomic profile of biological fluid. In proteomics studies, exclusion of contaminated samples is usually based on visual inspection and counting of red blood cells in the sample; analysis of specific blood derived proteins is less used. To fill the gap, we developed a fast and sensitive method for ascertainment of blood contamination in crude biological fluids, based on specific blood-derived protein, hemoglobin detection by MALDI-TOF MS. The MALDI-TOF MS based method allows detection of trace hemoglobin with the detection limit of 0.12 nM. UV-spectrometry, which was used as reference method, was found to be less sensitive. The main advantages of the presented method are that it is fast, effective, sensitive, requires very small sample amount and can be applied for detection of blood contamination in various biological fluids collected for proteomics studies. Method applicability was tested on human cerebrospinal and follicular fluid, which proteomes generally do not contain hemoglobin, however, which possess high risk for blood contamination. Present method successfully detected the blood contamination in 12 % of cerebrospinal fluid and 24 % of follicular fluid samples. High percentage of contaminated samples accentuates the need for initial inspection of proteomic samples to avoid incorrect results from blood proteome overlap.

  17. Assessment of Student Learning Associated with Tree Thinking in an Undergraduate Introductory Organismal Biology Course

    Science.gov (United States)

    Smith, James J.; Cheruvelil, Kendra Spence; Auvenshine, Stacie

    2013-01-01

    Phylogenetic trees provide visual representations of ancestor-descendant relationships, a core concept of evolutionary theory. We introduced "tree thinking" into our introductory organismal biology course (freshman/sophomore majors) to help teach organismal diversity within an evolutionary framework. Our instructional strategy consisted…

  18. An Assessment of the Quantitative Skills of Students Taking Introductory College Biology Courses.

    Science.gov (United States)

    Marsh, Jeffrey Flake; Anderson, Norman D.

    The mathematical skills possessed by students taking introductory biology courses were investigated. A list of 23 mathematical competencies was identified as part of the development of a 46-item multiple-choice test to measure the extent to which students possessed these competencies. The Biomathematics Skills Test (BST) was administered to…

  19. Formative Assessment and Increased Student Involvement Increase Grades in an Upper Secondary School Biology Course

    Science.gov (United States)

    Granbom, Martin

    2016-01-01

    This study shows that formative methods and increased student participation has a positive influence on learning measured as grades. The study was conducted during the course Biology A in a Swedish Upper Secondary School. The students constructed grade criteria and defined working methods and type of examination within a given topic, Gene…

  20. Using consumption rate to assess potential predators for biological control of white perch

    Science.gov (United States)

    Gosch, N.J.C.; Pope, K.L.

    2011-01-01

    Control of undesirable fishes is important in aquatic systems, and using predation as a tool for biological control is an attractive option to fishery biologists. However, determining the appropriate predators for biological control is critical for success. The objective of this study was to evaluate the utility of consumption rate as an index to determine the most effective predators for biological control of an invasive fish. Consumption rate values were calculated for nine potential predators that prey on white perch Morone americana in Branched Oak and Pawnee reservoirs, Nebraska. The consumption rate index provided a unique and insightful means of determining the potential effectiveness of each predator species in controlling white perch. Cumulative frequency distributions facilitated interpretation by providing a graphical presentation of consumption rates by all individuals within each predator species. Largemouth bass Micropterus salmoides, walleye Sander vitreus and sauger S. canadensis were the most efficient white perch predators in both reservoirs; however, previous attempts to increase biomass of these predators have failed suggesting that successful biological control is unlikely using existing predator species in these Nebraska reservoirs. ?? 2011 ONEMA.

  1. Is 'class effect' relevant when assessing the benefit/risk profile of a biologic agent?

    NARCIS (Netherlands)

    Sterry, W.; Kerkhof, P.C.M. van de

    2012-01-01

    Psoriasis is a chronic, genetically predisposed skin disorder, characterised by thickened scaly plaques. Although no therapy is recognised as curative, therapies aimed at symptom control include biologic agents that are generally designed to block molecular activation of cellular pathways of a patho

  2. Participation in introductory biology laboratories: An integrated assessment based on surveys, behavioral observations, and qualitative interviews

    Science.gov (United States)

    Russell, Connie Adelle

    Scope and method of study. The purpose of this study was to evaluate the effect of gender, major, and prior knowledge of and attitude toward biology on participation in introductory biology laboratories. Subjects for this study were 3,527 students enrolled in college-level introductory biology courses. During the study, three introductory courses were replaced with one mixed-majors course. The new course adopted a different pedagological approach from the previous courses in that an inquiry-based approach was used in lectures and laboratories. All subjects completed a survey that measured content knowledge using the NABT/NSTA High School Biology Examination Version 1990 and attitude using Russell and Hollander's Biology Attitude Scale. I used and discuss the merits of using ethological methods and data collection software, EthoScribeTM (Tima Scientific) to collect behavioral data from 145 students. I also evaluated participation using qualitative interviews of 30 students. I analyzed content knowledge and attitude data using ANOVA and Pearson correlation, and behavioral data using Contingency Table Analysis. I analyzed interviews following methods outlined by Rubin and Rubin. Findings. Course style and gender were the most useful variables in distinguishing differences among groups of students with regard to attitude, content knowledge, and participation in laboratories. Attitude toward biology and achievement measured by the surveys were found to be positively correlated; however, gender, major, class standing, course style and interactions between these variables also had effects on these variables. I found a positive association among attitude, achievement and participation in hands-on activities in laboratories. Differences in participation also were associated group type. In a traditional introductory biology course, females in single-gender groups, gender-equal, or groups in which females were the majority spent more time performing hands-on science

  3. 75 FR 69396 - Availability of an Environmental Assessment for a Biological Control Agent for Arundo donax

    Science.gov (United States)

    2010-11-12

    ... the control of Arundo donax (giant reed, Carrizo cane). The environmental assessment considers the..., prescribed fires, biomass removal, and other methods. However, these management measures are...

  4. Assessment of Biological Kinetics in a Conventional Municipal WWTP by Means of the Oxygen Uptake Rate Method

    Directory of Open Access Journals (Sweden)

    Vincenzo Torretta

    2014-04-01

    Full Text Available Pollution control of surface water bodies requires stringent checks on wastewater treatment plants performances. The satisfactory operation of biological treatment, commonly performed by means of activated sludge processes, requires a number of controlling and monitoring procedures. Suitable respirometric techniques for the determination of the kinetic parameters that regulate biological processes have been implemented in order to achieve this aim. This paper describes the results of an experimental research carried out in a conventional Italian municipal wastewater treatment plant. Particularly, the research has been finalized to both evaluate the biological process for the removal of biodegradable pollutants, such as carbonaceous substrates and ammonia nitrogen, and to collect data in order to evaluate a possible plant upgrade. Heterotrophic and autotrophic biomass kinetic parameters have been examined using respirometric techniques based on oxygen uptake measurements. The research performed makes a valuable contribution toward verifying the reliability of the values proposed in the literature for some kinetic parameters, which have been commonly used for a long time.

  5. Final report on the safety assessment of Cocos nucifera (coconut) oil and related ingredients.

    Science.gov (United States)

    Burnett, Christina L; Bergfeld, Wilma F; Belsito, Donald V; Klaassen, Curtis D; Marks, James G; Shank, Ronald C; Slaga, Thomas J; Snyder, Paul W; Andersen, F Alan

    2011-05-01

    Cocos nucifera (coconut) oil, oil from the dried coconut fruit, is composed of 90% saturated triglycerides. It may function as a fragrance ingredient, hair conditioning agent, or skin-conditioning agent and is reported in 626 cosmetics at concentrations from 0.0001% to 70%. The related ingredients covered in this assessment are fatty acids, and their hydrogenated forms, corresponding fatty alcohols, simple esters, and inorganic and sulfated salts of coconut oil. The salts and esters are expected to have similar toxicological profiles as the oil, its hydrogenated forms, and its constituent fatty acids. Coconut oil and related ingredients are safe as cosmetic ingredients in the practices of use and concentration described in this safety assessment.

  6. Environmental Safety and Health Analytical Laboratory, Pantex Plant, Amarillo, Texas. Final Environmental Assessment

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) has prepared an Environmental Assessment (EA) of the construction and operation of an Environmental Safety and Health (ES ampersand H) Analytical Laboratory and subsequent demolition of the existing Analytical Chemistry Laboratory building at Pantex Plant near Amarillo, Texas. In accordance with the Council on Environmental Quality requirements contained in 40 CFR 1500--1508.9, the Environmental Assessment examined the environmental impacts of the Proposed Action and discussed potential alternatives. Based on the analysis of impacts in the EA, conducting the proposed action, construction of an analytical laboratory and demolition of the existing facility, would not significantly effect the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA) and the Council on Environmental Quality regulations in 40 CFR 1508.18 and 1508.27

  7. Study to assess the potential uses of cost/benefit techniques. Final report

    International Nuclear Information System (INIS)

    The results of this study to assess potential uses of cost/benefit analysis are derived from application of probabilistic risk assessment (PRA) techniques to two design perspectives. They are (1) the evolution of design, regulation, and plant risk as applied to a representative BWR design, and (2) the risk values associated with various systems or system groups for a baseline BWR design. The PRA techniques were used to develop various quantitative indices of plant risk; these values can then be used with design cost information to derive cost/benefit analysis results. Quantitative results and some of their implications for the utility of cost/benefit analysis within the context of nuclear power plant design and regulation are discussed

  8. Process waste assessment: Black and white print/film processing and photomechanical transfer (PMT). Final report

    Energy Technology Data Exchange (ETDEWEB)

    Albers, D.L.

    1993-08-01

    This process waste assessment was performed to determine quantitatively the chemicals and materials used in the black and white print/film process, to determine their ultimate destination, and to explore options for reduced usage. It was determined that the volume of materials and water used for this process can be reduced; however, there would be significant restrictions on the types of reproductions available to customers. The process cannot be eliminated because of the classified artwork requirements.

  9. Pricing effects on frontier oil production. Final report. [Assessment by region

    Energy Technology Data Exchange (ETDEWEB)

    1977-06-20

    This study was designed to analyze and evaluate the price effect on the rate and cost of converting the resource potential of frontier regions to produced oil. The frontier regions studied were: (1) Alaska - Onshore (Regions 18 and 19); (2) Lower 48 - Onshore (Deep Horizon); (3) Alaska - Offshore (Regions 20 and 21); (4) Pacific Offshore (Region 22); (5) Gulf of Mexico (Region 24). A computer model was developed to assess probable exploitation scenarios of future oil reserves in these regions.

  10. Cost Quality Management Assessment for the Chicago Operations Office. Final report

    International Nuclear Information System (INIS)

    The Office of Engineering and Cost Evaluation (EM-24, now the Office of Engineering and Cost Management) conducted a Cost Quality Management Assessment (CQMA) at the Department of Energy (DOE) Chicago Operations Office (DOE-CH) on December 9--20, 1991. The CQMA team, composed of specialist from the Department of Energy, other Federal agencies, and the private sector used Performance objectives and Criteria (POCs) to assess the state of cost-management activities at DOE-CH. The Round II CQMA was conducted June 6--17, 1994, to examine DOE-CH's progress against its Action Plan and to review DOE-CH's cost and cost-related management practices against the POCs in the CQMA Site Handbook (Rev. 2). The interviews and document reviews conducted by CQMA team members show that DOE-CH has made commendable progress when practice is measured against the POCs. Of the 48 POCs discussed in this document, DOE-CH met 13 (28 %), partially met 32 (66 %), and did not meet only 3 (6 %). Noteworthy accomplishments at DOE-CH and the Argonne National Laboratory-East (ANL-E) include: (1) Preparation of an ANL-E CQMA Self-Assessment; (2) Development of the Argonne National Laboratory Project Management Manual; (3) Development of a corporate culture that recognizes the realities of cost and schedule constraints

  11. Characterization and assessment of potential European and Japanese competition in photovoltaics. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-10-01

    This study is an assessment of the potential of European and Japanese firms to produce and market photovoltaic (PV) power systems internationally in competition with firms in the United States. It consists of three distinct parts: (1) an overview of worldwide export activity which describes the general posture of selected European countries and Japan; (2) an assessment of European competition focusing on Germany, France, and the United Kingdom; and (3) an assessment of Japanese competition. All research was conducted within the United States relying on published reports in the scientific, trade, and business press; a firm's annual reports; and telephone interviews with representatives of European and Japanese firms. European and Japanese government representatives were also contacted and government-sponsored programs evaluated. European competition is addressed in three areas: characterization of the PV industry; current and potential marketing activity; and the status of PV and related technological developments. The same areas are addressed for depicting Japanese competition except that greater emphasis is placed on past industrial experience and related semiconductor sales.

  12. Central magnetic cooling and refrigeration machines (chiller) and their assessment. A feasibility study - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Egolf, P. W.; Gonin, C. [University of Applied Sciences of Western Switzerland, HEIG-VD, Yverdon-les Bains (Switzerland); Kitanovski, A. [University of Ljubljana, Ljubljana (Slovenia)

    2010-03-15

    This final report for the Swiss Federal Office of Energy (SFOE) presents the results of a feasibility study made concerning magnetic cooling and refrigeration machines. This report presents a comprehensive thermodynamic and economic analysis of applications of rotary magnetic chillers. The study deals with magnetic chillers based on permanent magnets and superconducting magnets, respectively. The numerical design of permanent magnet assemblies with different magnetic flux densities is discussed. The authors note that superconducting magnetic chillers are feasible only in large-scale applications with over 1 MW of cooling power. This report describes new ideas for magnetic refrigeration technologies, which go beyond the state of the art. They show potential for a substantial reduction of costs and further improvements in efficiency. Rotary magnetic liquid chillers with 'wavy' structures and using micro tubes are discussed, as are superconducting magnetic chillers and future magneto-caloric technologies.

  13. Summit-Watertown transmission line project, South Dakota. Final Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    The Western Area Power Administration (Western) needs to rebuild the existing Summit-Watertown 115-kV transmission line, located in northeastern South Dakota, and western Minnesota. Nearly 60 percent of the existing facility was replaced in 1965 after severe ice-loading broke structures and wires. Because of the extensive loss of the line, surplus poles had to be used to replace the damaged H-frame structures. These were of varying sizes, causing improper structure loading. Additionally, the conductors and overhead shield wires have been spliced in numerous places. This provides additional space on these wires for icing and wind resistance, which in turn create problems for reliability. Finally, a progressive fungal condition has weakened the poles and, along with the improper loading, has created an unsafe condition for maintenance personnel and the general public.

  14. Environmental assessment of nutrient recycling from biological pig slurry treatment--impact of fertilizer substitution and field emissions.

    Science.gov (United States)

    Brockmann, Doris; Hanhoun, Mary; Négri, Ophélie; Hélias, Arnaud

    2014-07-01

    Pig slurry treatment is an important means in reducing nitrogen loads applied to farmland. Solid phase separation prior to biological treatment further allows for recovering phosphorus with the solid phase. The organic residues from the pig slurry treatment can be applied as organic fertilizers to farmland replacing mineral fertilizers. The environmental impacts of nutrient recycling from aerobic, biological pig slurry treatment were evaluated applying the life cycle assessment (LCA) methodology. LCA results revealed that direct field emissions from organic fertilizer application and the amount of avoided mineral fertilizers dominated the environmental impacts. A modified plant available nitrogen calculation (PAN) was introduced taking into account calculated nitrogen emissions from organic fertilizer application. Additionally, an equation for calculating the quantity of avoided mineral fertilizers based on the modified PAN calculation was proposed, which accounted for nitrogen emissions from mineral fertilizer application.

  15. The Development and Application of Affective Assessment in an Upper-Level Cell Biology Course

    Science.gov (United States)

    Kitchen, Elizabeth; Reeve, Suzanne; Bell, John D.; Sudweeks, Richard R.; Bradshaw, William S.

    2007-01-01

    This study exemplifies how faculty members can develop instruments to assess affective responses of students to the specific features of the courses they teach. Means for assessing three types of affective responses are demonstrated: (a) student attitudes towards courses with differing instructional objectives and methodologies, (b) student…

  16. The impact of biology on risk assessment -- Workshop of the National Research Council`s board on radiation effects research. Meeting report

    Energy Technology Data Exchange (ETDEWEB)

    Fry, R.J.M. [Oak Ridge National Lab., TN (United States); Grosovsky, A. [Univ. of California, Riverside, CA (United States); Hanawalt, P.C. [Stanford Univ., CA (United States). Dept. of Biological Sciences; Jostes, R.F. [National Academy of Sciences, Washington, DC (United States). Board on Radiation Effects Research; Little, J.B. [Harvard School of Public Health, Boston, MA (United States). Dept. of Cancer Biology; Morgan, W.F. [Univ. of California, San Francisco, CA (United States). Dept. of Radiation Oncology; Oleinick, N.L. [Case Western Reserve Univ., Cleveland, OH (United States); Ullrich, R.L. [Univ. of Texas Medical Branch, Galveston, TX (United States). Dept. of Radiation Therapy

    1997-12-31

    The linear, nonthreshold extrapolation from a dose-response relationship for ionizing radiation derived at higher doses to doses for which regulatory standards are proposed is being challenged by some scientists and defended by others. It appears that the risks associated with exposures to doses of interest are below the risks that can be measured with epidemiologic studies. Therefore, many have looked to biology to provide information relevant to risk assessment. The workshop reported here, ``The Impact of biology on Risk Assessment,`` was planned to address the need for further information by bringing together scientists who have been working in key fields of biology and others who have been contemplating the issues associated specifically with this question. The goals of the workshop were to summarize and review the status of the relevant biology, to determine how the reported biologic data might influence risk assessment, and to identify subjects on which more data is needed.

  17. Assessment of biological effects of environmental pollution along the NW Mediterranean Sea using mussels as sentinel organisms

    Energy Technology Data Exchange (ETDEWEB)

    Zorita, Izaskun [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain); Apraiz, Itxaso [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain); Ortiz-Zarragoitia, Maren [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain); Orbea, Amaia [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain); Cancio, Ibon [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain); Soto, Manu [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain); Marigomez, Ionan [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain); Cajaraville, Miren P. [Biologia Zelularra eta Histologia Laborategia, Zoologia eta Biologia Zelularra Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea/Univ. del Pais Vasco, 644 P.K., E-48080 Bilbao, Basque Country (Spain)]. E-mail: mirenp.cajaraville@ehu.es

    2007-07-15

    With the aim of assessing the biological effects of pollution along three gradients of pollution in the NW Mediterranean Sea, a biomonitoring survey was implemented using a battery of biomarkers (lysosomal membrane stability, lysosomal structural changes, metallothionein (MT) induction and peroxisome proliferation) in mussels over a period of two years as part of the EU-funded BEEP project. Mussels from the most impacted zones (Fos, Genova and Barcelona harbours) showed enlarged lysosomes accompanied by reduced labilisation period of lysosomal membranes, indicating disturbed health. MT levels did not reveal significant differences between stations and were significantly correlated with gonad index, suggesting that they were influenced by gamete development. Peroxisomal acyl-CoA oxidase (AOX) activity was significantly inhibited in polluted stations possibly due to interactions among mixtures of pollutants. In conclusion, the application of a battery of effect and exposure biomarkers provided relevant data for the assessment of biological effects of environmental pollution along the NW Mediterranean Sea. - The biomarker approach is suitable for assessment of environmental pollution in the NW Mediterranean Sea.

  18. Hazard risk and vulnerability assessment : Regional District of Nanaimo : final report

    International Nuclear Information System (INIS)

    A Hazard Risk and Vulnerability Assessment (HRVA) is a mandated regulatory requirement in British Columbia that requires local authorities to prepare emergency plans that reflect the local authority's assessment of the relative risk of occurrence and the potential impact on people and property of the hazards, emergencies or disasters that could affect the jurisdictional area for which the local authority has responsibility. This report constituted an HRVA for the Regional District of Nanaimo, British Columbia. It presented the study scope and methodology and provided an overview of the Regional District of Nanaimo. This included information on the setting, demographics, and economy. Next, it discussed social vulnerability; critical response and recovery facilities; and critical infrastructure such as water, energy, telecommunications and transportation. A summary of the Regional District of Nanaimo's response capabilities that were considered when assessing the Regional District's overall risk to the hazards was also presented. Response capabilities were discussed with reference to fire and rescue; police; ambulance; and search and rescue. Emergency support and preparedness organizations were also identified. These included the Emergency Coordination Centre, environmental services, emergency social services, amateur radio and health authorities. Last, 33 hazards that could affect the Regional District of Nanaimo were identified and discussed. The study identified the following hazards as high risk: flooding; forest fires and wildland urban interface fires; and human diseases and pandemic. It was recommended that the advancement of business continuity planning in the Regional District of Nanaimo would help to reduce the impact of a possible human disease and pandemic risk outbreak affecting the population. 75 refs., 25 figs., 14 tabs., 2 appendices

  19. Selenium transformation in coal mine spoils: Its environmental impact assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Harness, J.; Atalay, A.; Koll, K.J.; Zhang, H.; Maggon, D.

    1991-12-31

    The objective of this program was to conduct an environmental impact assessment study for selenium from coal mine spoils. The use of in-situ lysimetry to predict selenium speciation, transformation, and mobility under natural conditions was evaluated. The scope of the study was to construct and test field-scale lysimeter and laboratory mini-column to assess mobility and speciation of selenium in coal mine overburden and soil systems; to conduct soil and groundwater sampling throughout the state of Oklahoma for an overall environmental impact assessment of selenium; and to conduct an in-depth literature review on the solubility, speciation, mobility, and toxicity of selenium from various sources. Groundwater and surface soil samples were also collected from each county in Oklahoma. Data collected from the lysimeter study indicated that selenium in the overburden of the abandoned mine site was mainly found in the selenite form. The amount of selenite found was too low and immobile to be of concern to the environment. The spoil had equilibrated long enough (over 50 years) that most of the soluble forms of selenium have already been lost. Examination of the overburden indicated the presence of pyrite crystals that precipitated over time. The laboratory mini-column study indicated that selenite is quite immobile and remained on the overburden material even after leaching with dilute acid. Data from groundwater samples indicated that based on the current permissible level for selenium in groundwater (0.01 mg Se/L), Oklahoma groundwater is widely contaminated with the element. However, according to the new regulation (0.05 mg Se/L), which is to be promulgated in 1992, only 9 of the 77 counties in the state exceed the limit.

  20. Hawaii demand-side management resource assessment. Final report: DSM opportunity report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    The Hawaii Demand-Side Management Resource Assessment was the fourth of seven projects in the Hawaii Energy Strategy (HES) program. HES was designed by the Department of Business, Economic Development, and Tourism (DBEDT) to produce an integrated energy strategy for the State of Hawaii. The purpose of Project 4 was to develop a comprehensive assessment of Hawaii`s demand-side management (DSM) resources. To meet this objective, the project was divided into two phases. The first phase included development of a DSM technology database and the identification of Hawaii commercial building characteristics through on-site audits. These Phase 1 products were then used in Phase 2 to identify expected energy impacts from DSM measures in typical residential and commercial buildings in Hawaii. The building energy simulation model DOE-2.1E was utilized to identify the DSM energy impacts. More detailed information on the typical buildings and the DOE-2.1E modeling effort is available in Reference Volume 1, ``Building Prototype Analysis``. In addition to the DOE-2.1E analysis, estimates of residential and commercial sector gas and electric DSM potential for the four counties of Honolulu, Hawaii, Maui, and Kauai through 2014 were forecasted by the new DBEDT DSM Assessment Model. Results from DBEDTs energy forecasting model, ENERGY 2020, were linked with results from DOE-2.1E building energy simulation runs and estimates of DSM measure impacts, costs, lifetime, and anticipated market penetration rates in the DBEDT DSM Model. Through its algorithms, estimates of DSM potential for each forecast year were developed. Using the load shape information from the DOE-2.1E simulation runs, estimates of electric peak demand impacts were developed. 10 figs., 55 tabs.

  1. Biological assessment of the advanced turbine design at Wanapum Dam, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Dauble, D. D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deng, Z. D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Richmond, M. C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Moursund, R. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carlson, T. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rakowski, C. L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Duncan, J. P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-08-01

    Three studies were conducted to evaluate the biological performance of an advanced design turbine installed at Unit 8 of Wanapum Dam on the Columbia River in 2005 versus a conventional Kaplan turbine, Unit 9. The studies included an evaluation of blade-strike using deterministic and probabilistic models, integrated analysis of the response of the Sensor Fish to sever hydraulic events within the turbine system, and a novel dye technique to measure injury to juvenile salmonids in the field.

  2. Double integrating spheres: A method for assessment of optical properties of biological tissues

    OpenAIRE

    Poppendieck, Wigand

    2004-01-01

    The determination of the optical properties of biological tissue is an important issue in laser medicine. The optical properties define the tissue´s absorption and scattering behaviour, and can be expressed by quantities such as the albedo, the optical thickness and the anisotropy coefficient. During this project, a measurement system for the determination of the optical properties was built up. The system consists of a double integrating sphere set-up to perform the necessary reflection and ...

  3. ENVIRONMENTAL ATTITUDES OF BIOLOGY TEACHER CANDIDATES AND THE ASSESSMENTS IN TERMS OF SOME VARIABLES

    OpenAIRE

    UĞULU, İlker; ERKOL, Sevilay

    2013-01-01

    Studying individuals and students' attitudes towards environment and factors affecting students to be responsible individuals towards their environment may provide help towards the solution of environmental problems. In this study, it is aimed to evaluate environmental attitudes of biology teacher candidates in terms of some variables. As a means of data collection, Environmental Attitude Scale and the personal information form have been used. Environmental Attitude Scale which has 35 items i...

  4. On-site assessment of methods to measure gaseous emissions from biological treatment of waste

    OpenAIRE

    Zdanevitch, Isabelle; Auvinet, N.; Mallard, Pascal; Bour, Olivier

    2012-01-01

    Landfilling of biodegradable waste must decrease to fulfil the Council Directive 99/31/EC on landfills, in order to reduce the emission of gaseous and liquid pollutants during the landfill lifetime. Therefore, pre-treatment of the organic fraction of municipal waste prior to landfilling is being developed in several countries. In France, the organic fraction is either separated and treated through selective collection of biowaste, or through mechanical sorting in the plant followed by biologi...

  5. Effects of organic amendment on soil quality as assessed by biological indicators

    OpenAIRE

    Sultana, Salma

    2011-01-01

    Soil quality decline is one of the most predominant effect deriving from human activities. In particular, intensive agricultural management can affect negatively soils, principally due to rapid depletion of soil organic matter, that affects, in turn, soil physical, chemical and biological properties. The declining trend of soil quality coupled with mismanagement of agricultural production is pose a serious threat to sustainability of intensive agriculture. Sustainable intensive agriculture is...

  6. Union County - La Grande, Oregon geothermal district heating: feasibility assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Jenkins, H. II; Giddings, M.; Hanson, P.

    1982-09-01

    This report presents an assessment of geothermal district heating in the City of La Grande, Oregon. Eight study area districts were analyzed to determine their economic feasibility. Results from the analyses conclude that certain districts within the City of La Grande are economically feasible if certain assumptions are correct. Development of geothermal district heating for these areas would provide direct energy and dollar savings to the building owners and would also provide direct and indirect benefits to low and moderate income households within the City.

  7. Final Report: Contractor Readiness Assessment (CRA) for TREAT Fuel Movement and Control Rod Drives Isolation

    International Nuclear Information System (INIS)

    This report documents the Contractor Readiness Assessment (CRA) for TREAT Fuel Movement and Control Rod Drives Isolation. The review followed the approved Plan of Action (POA) and Implementation Plan (IP) using the identified core requirements. The activity was limited scope focusing on the control rod drives functional isolation and fuel element movement. The purpose of this review is to ensure the facility's readiness to move fuel elements thus supporting inspection and functionally isolate the control rod drives to maintain the required shutdown margin.

  8. Geothermal resource assessment for the state of Texas: status of progress, November 1980. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Woodruff, C.M. Jr.; Caran, S.C.; Gever, C.; Henry, C.D.; Macpherson, G.L.; McBride, M.W.

    1982-03-01

    Data pertaining to wells and thermal aquifers and data interpretation methods are presented. Findings from a program of field measurements of water temperatures (mainly in South-Central Texas) and an assessment of hydrologic properties of three Cretaceous aquifers (in North-Central Texas) are included. Landsat lineaments and their pertinance to the localization of low-temperature geothermal resources are emphasized. Lineament data were compared to structural and stratigraphic features along the Balcones/Ouachita trend in Central Texas to test for correlations. (MHR)

  9. National environmental/energy workforce assessment. Texas. Final report on phase 1

    International Nuclear Information System (INIS)

    This study is one of 70 volumes assessing the workforce needs (manpower needs) for pollution control and abatement in the United States for the five-year period of 1976 through 1981. Seven fields for pollution control -- air, noise, pesticides, potable water, radiation, solid waste, and wastewater -- are analyzed, together with energy-related programs currently accentuated by the national effort to solve energy supply problems. The report identifies existing workforce levels, training programs, career opportunities, and future staffing level projections (1976 to 1982) based on the information available for the state of Texas

  10. Final Report: Contractor Readiness Assessment (CRA) for TREAT Fuel Movement and Control Rod Drives Isolation

    Energy Technology Data Exchange (ETDEWEB)

    Rowsell, David Leon [Idaho National Laboratory (INL), Idaho Falls, ID (United States)

    2015-06-01

    This report documents the Contractor Readiness Assessment (CRA) for TREAT Fuel Movement and Control Rod Drives Isolation. The review followed the approved Plan of Action (POA) and Implementation Plan (IP) using the identified core requirements. The activity was limited scope focusing on the control rod drives functional isolation and fuel element movement. The purpose of this review is to ensure the facility's readiness to move fuel elements thus supporting inspection and functionally isolate the control rod drives to maintain the required shutdown margin.

  11. Assessment report of research and development activities FY2014. Activity: 'Advanced science research' (Final report)

    International Nuclear Information System (INIS)

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for final evaluation and prior assessment of 'Advanced Science Research,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as 'ASRC') for the period of five years from April 2010 and the research programs from April 2015. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the results of the assessment by the Committee with the Committee report attached. (author)

  12. A new dimension of FDG-PET interpretation: assessment of tumor biology

    Energy Technology Data Exchange (ETDEWEB)

    Kwee, Thomas C. [University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Basu, Sandip [Tata Memorial Center Annexe, Radiation Medicine Center (Bhabha Atomic Research Center), Bombay (India); Hospital of the University of Pennsylvania, Division of Nuclear Medicine, Philadelphia, PA (United States); Saboury, Babak; Torigian, Drew A.; Alavi, Abass [Hospital of the University of Pennsylvania, Division of Nuclear Medicine, Philadelphia, PA (United States); Ambrosini, Valentina [Sant' Orsola-Malpighi University Hospital, Department of Nuclear Medicine, Bologna (Italy)

    2011-06-15

    {sup 18}F-Fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) is increasingly being used for the evaluation of several malignancies. Key to the correct interpretation of oncological FDG-PET studies is awareness of the concept that the degree of FDG uptake reflects the biology of the tumor in many cancers. More specifically, cancers with high FDG uptake are often histologically and clinically more aggressive than those with low or no FDG uptake. Therefore, although a negative FDG-PET scan in a patient with a cancer that has a size above the spatial resolution of PET may be interpreted as false-negative in terms of tumor detectability, it should in fact be regarded as true-negative from the view-point of tumor biology. This nonsystematic review will give examples of several major cancers in which the relationship between FDG avidity and tumor biology is applicable, and emphasizes the need to reconsider the definition of a ''false-negative'' FDG-PET scan in clinical oncology. (orig.)

  13. Sensor Fusion and Autonomy as a Powerful Combination for Biological Assessment in the Marine Environment

    Directory of Open Access Journals (Sweden)

    Mark A. Moline

    2016-02-01

    Full Text Available The ocean environment and the physical and biological processes that govern dynamics are complex. Sampling the ocean to better understand these processes is difficult given the temporal and spatial domains and sampling tools available. Biological systems are especially difficult as organisms possess behavior, operate at horizontal scales smaller than traditional shipboard sampling allows, and are often disturbed by the sampling platforms themselves. Sensors that measure biological processes have also generally not kept pace with the development of physical counterparts as their requirements are as complex as the target organisms. Here, we attempt to address this challenge by advocating the need for sensor-platform combinations to integrate and process data in real-time and develop data products that are useful in increasing sampling efficiencies. Too often, the data of interest is only garnered after post-processing after a sampling effort and the opportunity to use that information to guide sampling is lost. Here we demonstrate a new autonomous platform, where data are collected, analyzed, and data products are output in real-time to inform autonomous decision-making. This integrated capability allows for enhanced and informed sampling towards improving our understanding of the marine environment.

  14. Intergrated plant safety assessment. Systematic evaluation program. Palisades plant, Consumers Power Company, Docket No. 50-255. Final report

    International Nuclear Information System (INIS)

    The Nuclear Regulatory Commission (NRC) has published its Final Integrated Plant Safety Assessment Report (IPSAR) (NUREG-0820), under the scope of the Systematic Evaluation Program (SEP), for Consumers Power Company's Palisades Plant located in Covert, Van Buren County, Michigan. The SEP was initiated by the NRC to review the design of older operating nuclear reactor plants to reconfirm and document their safety. This report documents the review completed under the SEP for the Palisades Plant. The review has provided for (1) as assessment of the significance of differences between current technical positions on selected safety issues and those that existed when the Palisades Plant was licensed, (2) a basis for deciding on how these differences should be resolved in an integrated plant review, and (3) a documented evaluation of plant safety when all supplements to the Final IPSAR and the Safety Evaluation Report for converting the license from a provisional to a full-term license have been issued. The report also addresses the comments and recommendations made by the Advisory Committee on Reactor Safeguards in connection with its review of the Draft Report, issued in April 1982

  15. Comparison between full and tapered dosages of biologic therapies in psoriatic arthritis patients: clinical and ultrasound assessment.

    Science.gov (United States)

    Janta, Iustina; Martínez-Estupiñán, Lina; Valor, Lara; Montoro, María; Baniandres Rodriguez, Ofelia; Hernández Aragüés, Ignacio; Bello, Natalia; Hernández-Flórez, Diana; Hinojosa, Michelle; Martínez-Barrio, Julia; Nieto-González, Juan Carlos; Ovalles-Bonilla, Juan Gabriel; González, Carlos Manuel; López-Longo, Francisco Javier; Monteagudo, Indalecio; Naredo, Esperanza; Carreño, Luis

    2015-05-01

    The primary objective of this study was to describe and compare clinical and musculoskeletal (MS) ultrasound (US) features between psoriatic arthritis (PsA) patients treated with full and tapered dosage of biologic (b) disease-modified antirheumatic drugs (DMARDs). The secondary objective was to compare clinical and MSUS features between PsA patients treated with bDMARDs with and without concomitant synthetic (s) DMARDs. We evaluated 102 patients with PsA treated with bDMARDs. The bDMARD dosage tapering had been made in patients with a maintained remission or minimal disease activity (MDA) according to their attending rheumatologist and with the patient acceptance. The bDMARD tapering consisted of the following: increase the interval between doses for subcutaneous bDMARDs or reduction of the dose for intravenous bDMARDs. The clinical evaluation consisted of a dermatologic and rheumatologic assessment of disease activity. The presence of B-mode and Doppler synovitis, tenosynovitis, enthesopathy, and paratenonitis was investigated by a rheumatologist blinded to drug dosage, clinical assessments, and laboratory results. Seventy-four (72.5 %) patients received full dosage of bDMARDs and 28 (27.5 %) received tapered dosage. The duration with biologic therapy and with current biologic therapy was significantly higher in patients with tapered dosages (p = 0.008 and p = 0.001, respectively). We found no significant differences between clinical, laboratory, and US variables, both for BM and CD between patients with full and tapered dosage and between patients with and without concomitant sDMARD. Clinical assessment, MSUS variables, and MDA status are similar in patients receiving full and tapered dosage of bDMARDs. PMID:25636779

  16. Quantifying restoration success and recovery in a metal-polluted stream: A 17-year assessment of physicochemical and biological responses

    Science.gov (United States)

    Clements, W.H.; Vieira, N.K.M.; Church, S.E.

    2010-01-01

    Evaluating the effectiveness of stream restoration is often challenging because of the lack of pre-treatment data, narrow focus on physicochemical measures and insufficient post-restoration monitoring. Even when these fundamental elements are present, quantifying restoration success is difficult because of the challenges associated with distinguishing treatment effects from seasonal variation, episodic events and long-term climatic changes.2. We report results of one of the most comprehensive and continuous records of physical, chemical and biological data available to assess restoration success for a stream ecosystem in North America. Over a 17 year period we measured seasonal and annual changes in metal concentrations, physicochemical characteristics, macroinvertebrate communities, and brown trout Salmo trutta populations in the Arkansas River, a metal-contaminated stream in Colorado, USA.3. Although we observed significant improvements in water quality after treatment, the effectiveness of restoration varied temporally, spatially and among biological response variables. The fastest recovery was observed at stations where restoration eliminated point sources of metal contamination. Recovery of macroinvertebrates was significantly delayed at some stations because of residual sediment contamination and because extreme seasonal and episodic variation in metal concentrations prevented recolonization by sensitive species. Synthesis and applications. Because recovery trajectories after the removal of a stressor are often complex or nonlinear, long-term studies are necessary to assess restoration success within the context of episodic events and changes in regional climate. The observed variation in recovery among chemical and biological endpoints highlights the importance of developing objective criteria to assess restoration success. Although the rapid response of macroinvertebrates to reduced metal concentrations is encouraging, we have previously demonstrated that

  17. Assessing geothermal energy potential in upstate New York. Final report, Tasks 1, 3, and 4

    Energy Technology Data Exchange (ETDEWEB)

    Manger, K.C.

    1996-07-25

    New York State`s geothermal energy potential was evaluated based on a new resource assessment performed by the State University of New York at Buffalo (SUNY-Buffalo) and currently commercial technologies, many of which have become available since New York`s potential was last evaluated. General background on geothermal energy and technologies was provided. A life-cycle cost analysis was performed to evaluate the economics of using geothermal energy to generate electricity in upstate New York. A conventional rankine cycle, binary power system was selected for the economic evaluation, based on SUNY-Buffalo`s resource assessment. Binary power systems are the most technologically suitable for upstate New York`s resources and have the added advantage of being environmentally attractive. Many of the potential environmental impacts associated with geothermal energy are not an issue in binary systems because the geothermal fluids are contained in a closed-loop and used solely to heat a working fluid that is then used to generate the electricity Three power plant sizes were selected based on geologic data supplied by SUNY-Buffalo. The hypothetical power plants were designed as 5 MW modular units and sized at 5 MW, 10 MW and 15 MW. The life-cycle cost analysis suggested that geothermal electricity in upstate New York, using currently commercial technology, will probably cost between 14 and 18 cents per kilowatt-hour.

  18. Impact assessment of the 1977 New York City blackout. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Corwin, J. L.; Miles, W. T.

    1978-07-01

    This study was commissioned by the Division of Electric Energy Systems (EES), Department of Energy (DOE) shortly after the July 13, 1977 New York City Blackout. The objectives were two-fold: to assess the availability and collect, where practical, data pertaining to a wide variety of impacts occurring as a result of the blackout; and to broadly define a framework to assess the value of electric power reliability from consideration of the blackout and its effects on individuals, businesses, and institutions. The impacts were complex and included both economic and social costs. In order to systematically classify the most significant of these impacts and provide guidance for data collection, impact classification schemes were developed. Major economic impact categories examined are business; government; utilities (Consolidated Edison); insurance industry; public health services; and other public services. Impacts were classified as either direct or indirect depending upon whether the impact was due to a cessation of electricity or a response to that cessation. The principal economic costs of the blackout are shown. Social impacts, i.e., the changes in social activities and adaptations to these changes were particularly significant in New York due to its unique demographic and geographic characteristics. The looting and arson that accompanied the blackout set aside the NYC experience from other similar power failures. (MCW)

  19. Investigation of oil drilling impacts to aquatic habitat resources: In Situ biological assessment of the photoinduced toxicity of environmental releases of crude oil

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This study proposed a biological assessment of a recent crude oil spill for potential impacts to aquatic resources due to petroleum hydrocarbon wastes. The...

  20. Final Environmental Assessment Proposed Opening of Bogue Chitto National Wildlife Refuge to Upland Game Hunting, Migratory Waterfowl Hunting, Big Game Hunting and Sport and Commercial Fishing

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — 1985 Final Environmental Assessment Proposed Opening of Bogue Chitto National Wildlife Refuge to Upland Game Hunting, Migratory Waterfoul Hunting, Big Game Hunting...

  1. Bioavailability of Organic Solvents in Soils: Input into Biologically Based Dose-Response Models for Human Risk Assessments - Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Webster, R. C.

    2000-10-01

    Compared to dermal exposures with neat or aqueous compound, little is understood about the dermal bioavailability of solvents in soil, dust, sludge, or sediment matrices. Therefore, research in this project was designed to provide an understanding of the influence of various environmental factors on the kinetics and bioavailability of solvent-laden soils.

  2. Ocean Thermal Energy Conversion Life Cycle Cost Assessment, Final Technical Report, 30 May 2012

    Energy Technology Data Exchange (ETDEWEB)

    Martel, Laura [Lockheed Martin, Manassas, VA (United States); Smith, Paul [John Halkyard and Associates: Glosten Associates, Houston, TX (United States); Rizea, Steven [Makai Ocean Engineering, Waimanalo, HI (United States); Van Ryzin, Joe [Makai Ocean Engineering, Waimanalo, HI (United States); Morgan, Charles [Planning Solutions, Inc., Vancouver, WA (United States); Noland, Gary [G. Noland and Associates, Inc., Pleasanton, CA (United States); Pavlosky, Rick [Lockheed Martin, Manassas, VA (United States); Thomas, Michael [Lockheed Martin, Manassas, VA (United States); Halkyard, John [John Halkyard and Associates: Glosten Associates, Houston, TX (United States)

    2012-05-30

    The Ocean Thermal Energy Conversion (OTEC) Life Cycle Cost Assessment (OLCCA) is a study performed by members of the Lockheed Martin (LM) OTEC Team under funding from the Department of Energy (DOE), Award No. DE-EE0002663, dated 01/01/2010. OLCCA objectives are to estimate procurement, operations and maintenance, and overhaul costs for two types of OTEC plants: -Plants moored to the sea floor where the electricity produced by the OTEC plant is directly connected to the grid ashore via a marine power cable (Grid Connected OTEC plants) -Open-ocean grazing OTEC plant-ships producing an energy carrier that is transported to designated ports (Energy Carrier OTEC plants) Costs are developed using the concept of levelized cost of energy established by DOE for use in comparing electricity costs from various generating systems. One area of system costs that had not been developed in detail prior to this analysis was the operations and sustainment (O&S) cost for both types of OTEC plants. Procurement costs, generally referred to as capital expense and O&S costs (operations and maintenance (O&M) costs plus overhaul and replacement costs), are assessed over the 30 year operational life of the plants and an annual annuity calculated to achieve a levelized cost (constant across entire plant life). Dividing this levelized cost by the average annual energy production results in a levelized cost of electricity, or LCOE, for the OTEC plants. Technical and production efficiency enhancements that could result in a lower value of the OTEC LCOE were also explored. The thermal OTEC resource for Oahu, Hawaii and projected build out plan were developed. The estimate of the OTEC resource and LCOE values for the planned OTEC systems enable this information to be displayed as energy supplied versus levelized cost of the supplied energy; this curve is referred to as an Energy Supply Curve. The Oahu Energy Supply Curve represents initial OTEC deployment starting in 2018 and demonstrates the

  3. Preliminary emissions assessment of conventional stationary combustion systems. Volume II. Final report, Mar--Dec 1975

    International Nuclear Information System (INIS)

    The report gives results of a preliminary emissions assessment of the air, water, and solid waste pollutants produced by conventional stationary combustion systems. It gives results in four principal categories: utilities (electric generation), industrial (steam generation, space heating, and stationary engines), commercial/institutional (space heating and stationary engines), and residential (space heating). For each principal combustion system category, it gives: process types and operating efficiencies, fuel consumption, pollutant sources and characteristics, major research and development trends, fuel consumption trends, and technical areas where emission data are incomplete or unreliable. It also gives the pollutant emissions from applicable unit operations for each of 56 source classifications, using a uniform combustion source classification system. It identifies major gaps in available data regarding the population and capacity of combustion systems, application of control measures, fuel composition, and other parameters which significantly influence pollutant characteristics and emission rates

  4. Assessing middle school students` understanding of science relationships and processes. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Schau, C.; Mattern, N.; Weber, R. [Univ. of New Nexico, Albuquerque, NM (United States); Minnick, K. [Minnick & Associates, Inc., Albuquerque, NM (United States)

    1994-09-01

    Our overall goal for this multi-year project is to develop and validate an alternative assessment format that effectively measures middle school students understanding of the relationships among selected science concepts and processes. In this project, we collaborate with the staff of the Los Alamos National Laboratory`s TOPS Program and the Programs participating teachers and their students. We also work with selected middle school science teachers from the TOPS program at Sandia National Laboratories. Our goal for this past year was to develop and field test informally a variety of potential measurement formats. This work has allowed us to identify formats to test during the validation phase of the project which will occur during the second year.

  5. Lower Yakima Valley Wetlands and Riparian Restoration Project. Final environmental assessment

    International Nuclear Information System (INIS)

    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Mitigation Agreement pertaining to the Lower Yakima Valley Wetlands and Riparian Restoration Project (Project) in a cooperative effort with the Yakama Indian Nation and the Bureau of Indian Affairs (BIA). The proposed action would allow the sponsors to secure property and conduct wildlife management activities for the Project within the boundaries of the Yakama Indian Reservation. This Environmental Assessment examines the potential environmental effects of acquiring and managing property for wildlife and wildlife habitat within a large 20, 340 hectare (50, 308 acre) project area. As individual properties are secured for the Project, three site-specific activities (habitat enhancement, operation and maintenance, and monitoring and evaluation) may be subject to further site-specific environmental review. All required Federal/Tribal coordination, permits and/or approvals would be obtained prior to ground disturbing activities

  6. State-coupled low temperature geothermal resource assessment program, fiscal year 1982. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Icerman, Larry

    1983-08-01

    This report summarizes the results of low-temperature geothermal energy resource assessment efforts in New Mexico during the period from June 15, 1981 through September 30, 1983, under the sponsorship of the US Department of Energy (Contract DE-AS07-78ID01717). The report is divided into four chapters which correspond to the tasks delineated in the contract. Chapter 5 is a brief summary of the tasks performed under this contract during the period October 1, 1978, through June 30, 1983. This work extends the knowledge of low-temperature geothermal reservoirs with the potential for direct heating applications in New Mexico. The research effort focused on compiling basic geothermal data throughout selected areas in New Mexico in a format suitable for direct transfer to the US Geological Survey for inclusion in the GEOTHERM data file and to the National Oceanic and Atmospheric Administration for use with New Mexico geothermal resources maps.

  7. Lower Yakima Valley Wetlands and Riparian Restoration Project. Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration

    1994-10-01

    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Mitigation Agreement pertaining to the Lower Yakima Valley Wetlands and Riparian Restoration Project (Project) in a cooperative effort with the Yakama Indian Nation and the Bureau of Indian Affairs (BIA). The proposed action would allow the sponsors to secure property and conduct wildlife management activities for the Project within the boundaries of the Yakama Indian Reservation. This Environmental Assessment examines the potential environmental effects of acquiring and managing property for wildlife and wildlife habitat within a large 20, 340 hectare (50, 308 acre) project area. As individual properties are secured for the Project, three site-specific activities (habitat enhancement, operation and maintenance, and monitoring and evaluation) may be subject to further site-specific environmental review. All required Federal/Tribal coordination, permits and/or approvals would be obtained prior to ground disturbing activities.

  8. Review of international geothermal activities and assessment of US industry opportunities: Final report

    Energy Technology Data Exchange (ETDEWEB)

    1987-08-01

    This study was initiated to review and assess international developments in the geothermal energy field and to define business opportunities for the US geothermal industry. The report establishes data bases on the status of worldwide geothermal development and the competitiveness of US industry. Other factors identified include existing legislation, tax incentives, and government institutions or agencies and private sector organizations that promote geothermal exports. Based on the initial search of 177 countries and geographic entities, 71 countries and areas were selected as the most likely targets for the expansion of the geothermal industry internationally. The study then determined to what extent their geothermal resource had been developed, what countries had aided or participated in this development, and what plans existed for future development. Data on the energy, economic, and financial situations were gathered.

  9. Tucannon River Spring Chinook Captive Broodstock Program Final Environmental Assessment and Finding of No Significant Impact

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    2000-05-24

    Bonneville Power Administration (BPA) is proposing to fund the Tucannon River Spring Chinook Captive Broodstock Program, a small-scale production initiative designed to increase numbers of a weak but potentially recoverable population of spring chinook salmon in the Tucannon River in the State of Washington. BPA has prepared an Environmental Assessment (EA) (DOE/EA-l326) evaluating the proposed project. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and BPA is issuing this Finding of No Significant Impact (FONSI).

  10. Coal liquefaction: A research and development needs assessment: Final report, Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Schindler, H.D.; Burke, F.P.; Chao, K.C.; Davis, B.H.; Gorbaty, M.L.; Klier, K.; Kruse, C.W.; Larsen, J.W.; Lumpkin, R.E.; McIlwain, M.E.; Wender, I.; Stewart, N.

    1989-03-01

    Volume II of this report on an assessment of research needs for coal liquefaction contains reviews of the five liquefaction technologies---direct, indirect, pyrolysis, coprocessing, and bioconversion. These reviews are not meant to be encyclopedic; several outstanding reviews of liquefaction have appeared in recent years and the reader is referred to these whenever applicable. Instead, these chapters contain reviews of selected topics that serve to support the panel's recommendations or to illustrate recent accomplishments, work in progress, or areas of major research interest. At the beginning of each of these chapters is a brief introduction and a summary of the most important research recommendations brought out during the panel discussions and supported by the material presented in the review. A review of liquefaction developments outside the US is included. 594 refs., 100 figs., 60 tabs.

  11. Mid-Columbia Coho Reintroduction Feasibility Project : Final Environmental Assessment and Finding of No Significant Impact.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration; Confederated Tribes and Bands of the Yakama Nation; Washington State Department of Fish and Wildlife

    1999-04-01

    Bonneville Power Administration (BPA) is proposing to fund research for 2 to 3 years on the feasibility of reintroducing coho salmon into mid-Columbia River basin tributaries. The research would take place in the Methow and Wenatchee river basins in Chelan and Okanogan Counties, Washington. BPA has prepared an Environmental Assessment (EA) (DOE/EA-1282) evaluating the proposed project. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and BPA is issuing this Finding of No Significant Impact.

  12. Mid-Columbia Coho Reintroduction Feasibility Project. Final Environmental Assessment and Finding of No Significant Impact

    International Nuclear Information System (INIS)

    Bonneville Power Administration (BPA) is proposing to fund research for 2 to 3 years on the feasibility of reintroducing coho salmon into mid-Columbia River basin tributaries. The research would take place in the Methow and Wenatchee river basins in Chelan and Okanogan Counties, Washington. BPA has prepared an Environmental Assessment (EA) (DOE/EA-1282) evaluating the proposed project. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and BPA is issuing this Finding of No Significant Impact

  13. Final environmental assessment: Los Reales 115 kV transmission line alternative routes

    Energy Technology Data Exchange (ETDEWEB)

    1989-10-01

    The Central Arizona Project (CAP) was authorized as a part of the Colorado River Basin Project Act (Public Law 90-537) on September 30, 1968. The primary purpose of the CAP is to furnish water for agricultural, municipal, and industrial uses in central and southern Arizona, and western New Mexico. Due to its magnitude, the CAP is divided into several major features serving separate but interrelated functions. The Tucson Aqueduct Phase B pumping plants were designed and constructed to operate on a looped power system. The entire looped power system, including two switching stations and connecting 115-kv transmission lines, was identified in the FEIS and approved for construction in the Secretary of Interior's Record of Decision dated September 24, 1985. The loop begins in the vicinity of the Twin Peaks Pumping Plant -- the northernmost Phase B pumping station, at the Rattlesnake Switching Station. All of the looped power system has been constructed with the exception of the switching station and portion of transmission line proposed to be constructed in this project. Without construction of this final portion of the looped power system, the Phase B pumping plants will not be able to operate normally without negatively affecting nearby power sources. The CAP will also not be able to provide the reliability necessary for municipal water systems dependent upon CAP water. The purpose of this EA is to describe impacts that would result from relocating the Los Reales 115-kV transmission line, and possibly the switching station, originally identified in the FEIS. It should be mentioned the Department of Energy will complete a separate NEPA review.

  14. HYDRO BIOLOGICAL ASSESSMENT OF WATER BODIES FROM MIRAJ TAHSIL MAHARASHTRA: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    A. B. Sarwade

    2014-09-01

    Full Text Available Physicochemical features of freshwater bodies were regulated by number of factors. It includes temperature, turbidity, pH, total alkalinity, carbondioxide, dissolved oxygen, biological oxygen demand, chemical oxygen demand, phosphate, chloride and hardness. Present study focused on the determination of hydrobiological parameters during different seasons in January, 2011 – December, 2013 in three lakes of Miraj tahsil. The study indicated marked variation in some of the factors as turbidity, CO₂, DO, COD, Alkalinity etc. Obtained data showed, variations in pollution status of three lakes. As per observations and analysis contamination of lakes was Bharatnagar > Mhaishal > Brahmanath lake.

  15. A saprobic index for biological assessment of river water quality in Brazil (Minas Gerais and Rio de Janeiro states).

    Science.gov (United States)

    Junqueira, Marilia Vilela; Friedrich, Günther; Pereira de Araujo, Paulo Roberto

    2010-04-01

    Based upon several years of experience in investigations with macrozoobenthos in rivers in the states of Minas Gerais and Rio de Janeiro, a biological assessment system has been developed to indicate pollution levels caused by easily degradable organic substances from sewers. The biotic index presented here is aimed at determining water's saprobic levels and was, therefore, named the "Saprobic Index for Brazilian Rivers in Minas Gerais and Rio de Janeiro states" (ISMR). For this purpose, saprobic valences and weights have been established for 122 taxa of tropical macrozoobenthos. Investigations were carried out in little, medium sized and big rivers in mountains and plains. Through ISMR, a classification of water quality and the respective cartographic representation can be obtained. Data collection and treatment methods, as well as the limitations of the biotic index, are thoroughly described. ISMR can also be used as an element to establish complex multimetric indexes intended for an ecological integrity assessment, where it is essential to indicate organic pollution.

  16. Life cycle assessment of biomass-to-liquid fuels - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Jungbluth, N.; Buesser, S.; Frischknecht, R.; Tuchschmid, M.

    2008-02-15

    This study elaborates a life cycle assessment of using of BTL-fuels (biomass-to-liquid). This type of fuel is produced in synthesis process from e.g. wood, straw or other biomass. The life cycle inventory data of the fuel provision with different types of conversion concepts are based on the detailed life cycle assessment compiled and published within a European research project. The inventory of the fuel use emissions is based on information published by automobile manufacturers on reductions due to the use of BTL-fuels. Passenger cars fulfilling the EURO3 emission standards are the basis for the comparison. The life cycle inventories of the use of BTL-fuels for driving in passenger cars are investigated from cradle to grave. The full life cycle is investigated with the transportation of one person over one kilometre (pkm) as a functional unit. This includes all stages of the life cycle of a fuel (biomass and fuel production, distribution, combustion) and the necessary infrastructure (e.g. tractors, conversion plant, cars and streets). The use of biofuels is mainly promoted for the reason of reducing the climate change impact and the use of scarce non-renewable resources e.g. crude oil. The possible implementation of BTL-fuel production processes would potentially help to achieve this goal. The emissions of greenhouse gases due to transport services could be reduced by 28% to 69% with the BTL-processes using straw, forest wood or short-rotation wood as a biomass input. The reduction potential concerning non-renewable energy resources varies between 37% und 61%. A previous study showed that many biofuels cause higher environmental impacts than fossil fuels if several types of ecological problems are considered. The study uses two single score impact assessment methods for the evaluation of the overall environmental impacts, namely the Eco-indicator 99 (H,A) and the Swiss ecological scarcity 2006 method. The transportation with the best BTL-fuel from short

  17. Racial bias in pain assessment and treatment recommendations, and false beliefs about biological differences between blacks and whites.

    Science.gov (United States)

    Hoffman, Kelly M; Trawalter, Sophie; Axt, Jordan R; Oliver, M Norman

    2016-04-19

    Black Americans are systematically undertreated for pain relative to white Americans. We examine whether this racial bias is related to false beliefs about biological differences between blacks and whites (e.g., "black people's skin is thicker than white people's skin"). Study 1 documented these beliefs among white laypersons and revealed that participants who more strongly endorsed false beliefs about biological differences reported lower pain ratings for a black (vs. white) target. Study 2 extended these findings to the medical context and found that half of a sample of white medical students and residents endorsed these beliefs. Moreover, participants who endorsed these beliefs rated the black (vs. white) patient's pain as lower and made less accurate treatment recommendations. Participants who did not endorse these beliefs rated the black (vs. white) patient's pain as higher, but showed no bias in treatment recommendations. These findings suggest that individuals with at least some medical training hold and may use false beliefs about biological differences between blacks and whites to inform medical judgments, which may contribute to racial disparities in pain assessment and treatment. PMID:27044069

  18. Assessment of the effectiveness of an industrial unit of mechanical-biological treatment of municipal solid waste.

    Science.gov (United States)

    Bayard, R; Morais, J de Araújo; Ducom, G; Achour, F; Rouez, M; Gourdon, R

    2010-03-15

    An assessment of the French municipal solid waste (MSW) mechanical-biological treatment (MBT) unit of Mende was performed in terms of mass reduction, biogas emissions reduction and biostability of the biologically treated waste. The MBT unit consists of mechanical sorting operations, an aerobic rotating bioreactor, forced-aeration process in open-air tunnels (stabilization), ripening platforms and a sanitary landfill site for waste disposal in separated cells. On the overall plant, results showed a dry matter reduction of 18.9% and an oxidative organic matter reduction of 39.0%. A 46.2% biogas production decrease could also be observed. Concerning the biotreatment steps, high reductions were observed: 88.1% decrease of biogas potential and 57.7% decrease of oxidative organic matter content. Nevertheless, the usually considered stabilization indices (biogas potential, respirometric index) remained higher than recommended by the German or Austrian regulation for landfilling. Mass balance performed on each step of the treatment line showed that several stages needed improvement (especially mechanical sorting operations) as several waste fractions containing potentially biodegradable matter were landfilled with very few or no biological treatment. PMID:19913357

  19. Assessment of the effectiveness of an industrial unit of mechanical-biological treatment of municipal solid waste

    Energy Technology Data Exchange (ETDEWEB)

    Bayard, R., E-mail: remy.bayard@insa-lyon.fr [Universite de Lyon, INSA-Lyon, Laboratoire de Genie Civil et d' Ingenierie Environnementale LGCIE, 20 avenue Albert Einstein, F-69621 Villeurbanne (France); Araujo Morais, J. de; Ducom, G.; Achour, F.; Rouez, M.; Gourdon, R. [Universite de Lyon, INSA-Lyon, Laboratoire de Genie Civil et d' Ingenierie Environnementale LGCIE, 20 avenue Albert Einstein, F-69621 Villeurbanne (France)

    2010-03-15

    An assessment of the French municipal solid waste (MSW) mechanical-biological treatment (MBT) unit of Mende was performed in terms of mass reduction, biogas emissions reduction and biostability of the biologically treated waste. The MBT unit consists of mechanical sorting operations, an aerobic rotating bioreactor, forced-aeration process in open-air tunnels (stabilization), ripening platforms and a sanitary landfill site for waste disposal in separated cells. On the overall plant, results showed a dry matter reduction of 18.9% and an oxidative organic matter reduction of 39.0%. A 46.2% biogas production decrease could also be observed. Concerning the biotreatment steps, high reductions were observed: 88.1% decrease of biogas potential and 57.7% decrease of oxidative organic matter content. Nevertheless, the usually considered stabilization indices (biogas potential, respirometric index) remained higher than recommended by the German or Austrian regulation for landfilling. Mass balance performed on each step of the treatment line showed that several stages needed improvement (especially mechanical sorting operations) as several waste fractions containing potentially biodegradable matter were landfilled with very few or no biological treatment.

  20. Assessment of the effectiveness of an industrial unit of mechanical-biological treatment of municipal solid waste

    International Nuclear Information System (INIS)

    An assessment of the French municipal solid waste (MSW) mechanical-biological treatment (MBT) unit of Mende was performed in terms of mass reduction, biogas emissions reduction and biostability of the biologically treated waste. The MBT unit consists of mechanical sorting operations, an aerobic rotating bioreactor, forced-aeration process in open-air tunnels (stabilization), ripening platforms and a sanitary landfill site for waste disposal in separated cells. On the overall plant, results showed a dry matter reduction of 18.9% and an oxidative organic matter reduction of 39.0%. A 46.2% biogas production decrease could also be observed. Concerning the biotreatment steps, high reductions were observed: 88.1% decrease of biogas potential and 57.7% decrease of oxidative organic matter content. Nevertheless, the usually considered stabilization indices (biogas potential, respirometric index) remained higher than recommended by the German or Austrian regulation for landfilling. Mass balance performed on each step of the treatment line showed that several stages needed improvement (especially mechanical sorting operations) as several waste fractions containing potentially biodegradable matter were landfilled with very few or no biological treatment.

  1. The French photovoltaic sector: assessment, perspectives and strategy. September 2015 - Final report

    International Nuclear Information System (INIS)

    This study aims at proposing a strategy to support the development of the photovoltaic sector in France between 2016 and 2020. It is based on a quantitative survey of 1.200 French actors, and on interviews with more than 50 key actors. This study was also an opportunity to model costs, profitability, and jobs all along the value chain of the photovoltaic sector. It also proposes a return on experience from other countries. It analyses and discusses the current evolution of the photovoltaic market and sector in the world and in France. As far as the French market is concerned, it shows that a development without subsidy will be possible from 2020 and on. It reports a contrasted assessment of the French photovoltaic public policy, highlights that this sector is still seeking its position. It describes how the four years to come (2016-2020) are an opportunity to implement a strong-willed public policy for a competitive photovoltaic sector and a stronger French sector. It notably outlines that ZNI (non interconnected areas) are an opportunity for tools of integration to the grid

  2. Technology assessment of vertical and horizontal air drilling potential in the United States. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Carden, R.S.

    1993-08-18

    The objective of the research was to assess the potential for vertical, directional and horizontal air drilling in the United States and to evaluate the current technology used in air drilling. To accomplish the task, the continental United States was divided into drilling regions and provinces. The map in Appendix A shows the divisions. Air drilling data were accumulated for as many provinces as possible. The data were used to define the potential problems associated with air drilling, to determine the limitations of air drilling and to analyze the relative economics of drilling with air versus drilling mud. While gathering the drilling data, operators, drilling contractors, air drilling contractors, and service companies were contacted. Their opinion as to the advantages and limitations of air drilling were discussed. Each was specifically asked if they thought air drilling could be expanded within the continental United States and where that expansion could take place. The well data were collected and placed in a data base. Over 165 records were collected. Once in the data base, the information was analyzed to determine the economics of air drilling and to determine the limiting factors associated with air drilling.

  3. Final environmental assessment: TRU waste drum staging building, Technical Area 55, Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Much of the US Department of Energy's (DOE's) research on plutonium metallurgy and plutonium processing is performed at Los Alamos National Laboratory (LANL), in Los Alamos, New Mexico. LANL's main facility for plutonium research is the Plutonium Facility, also referred to as Technical Area 55 (TA-55). The main laboratory building for plutonium work within the Plutonium Facility (TA-55) is the Plutonium Facility Building 4, or PF-4. This Environmental Assessment (EA) analyzes the potential environmental effects that would be expected to occur if DOE were to stage sealed containers of transuranic (TRU) and TRU mixed waste in a support building at the Plutonium Facility (TA-55) that is adjacent to PF-4. At present, the waste containers are staged in the basement of PF-4. The proposed project is to convert an existing support structure (Building 185), a prefabricated metal building on a concrete foundation, and operate it as a temporary staging facility for sealed containers of solid TRU and TRU mixed waste. The TRU and TRU mixed wastes would be contained in sealed 55-gallon drums and standard waste boxes as they await approval to be transported to TA-54. The containers would then be transported to a longer term TRU waste storage area at TA-54. The TRU wastes are generated from plutonium operations carried out in PF-4. The drum staging building would also be used to store and prepare for use new, empty TRU waste containers

  4. Integrated assessment of acid deposition impacts using reduced-form modeling. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sinha, R.; Small, M.J.

    1996-05-01

    Emissions of sulfates and other acidic pollutants from anthropogenic sources result in the deposition of these acidic pollutants on the earth`s surface, downwind of the source. These pollutants reach surface waters, including streams and lakes, and acidify them, resulting in a change in the chemical composition of the surface water. Sometimes the water chemistry is sufficiently altered so that the lake can no longer support aquatic life. This document traces the efforts by many researchers to understand and quantify the effect of acid deposition on the water chemistry of populations of lakes, in particular the improvements to the MAGIC (Model of Acidification of Groundwater in Catchments) modeling effort, and describes its reduced-form representation in a decision and uncertainty analysis tool. Previous reduced-form approximations to the MAGIC model are discussed in detail, and their drawbacks are highlighted. An improved reduced-form model for acid neutralizing capacity is presented, which incorporates long-term depletion of the watershed acid neutralization fraction. In addition, improved fish biota models are incorporated in the integrated assessment model, which includes reduced-form models for other physical and chemical processes of acid deposition, as well as the resulting socio-economic and health related effects. The new reduced-form lake chemistry and fish biota models are applied to the Adirondacks region of New York.

  5. A research needs assessment: Energy efficient alternatives to chlorofluorocarbons (CFCs). Final reprot

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    An assessment of the state of the art in refrigeration and insulation technologies is carried out to evaluate the potential for efficient substitutes for CFCs and HCFCs to facilitate the transition to a CFC-free environment. Opportunities for improved efficiency in domestic refrigeration, building chillers, commercial refrigeration and industrial refrigeration are evaluated. Needs for alternate refrigerants, improved components, and/or alternate cycles are identified. A summary of on-going research is presented in each area, and the potential roles of industry and government are considered. The most promising approaches for refrigeration technology fall into these categories: (1) improved vapor compressor cycles with alternate fluids, (2) Stirling cycle development and (3) advances in absorption technology. A summary of on-going research into advanced insulation, focused on vacuum -- based insulation technology refrigeration is developed. Insulation applications considered include appliances, transport refrigeration, and buildings. Specific recommendations for a long-term R&D agenda are present. The potential benefits, research, general approach, and probability of success are addressed.

  6. Final Report: Risk assessment for produced water discharges to Louisiana open bays

    Energy Technology Data Exchange (ETDEWEB)

    Meinhold, A.F.; DePhillips, M.P.; Holtzman, S.

    1996-03-01

    Potential human health and environmental impacts from discharges of produced water to the Gulf of Mexico are of concern to regulators at the State and Federal levels, the public, environmental interest groups and industry. Current and proposed regulations require a zero discharge limit for coastal facilities, based primarily on studies in low energy, poorly flushed environments. However, produced water discharges in coastal Louisiana include a number of open bay sites, where potential human health and environmental impacts are likely to be smaller than those demonstrated for low energy canal environments, but greater than the minimal impacts associated with offshore discharges. Additional data and assessments are needed to support risk managers at the State and Federal levels in the development of regulations that protect human health and the environment without unnecessary cost to the economic welfare of the region and the nation. This project supports the Natural Gas and Oil Initiative objectives to: (1) improve coordination on environmental research; (2) streamline State and Federal regulation; (3) enhance State, and Federal regulatory decision making capability; (4) enhance dialogue through industry/government/public partnerships; and (5) work with States and Native American Tribes.

  7. Beaufort Region Environmental Assessment and Monitoring program (BREAM). Final report for 1992/1993

    International Nuclear Information System (INIS)

    The Beaufort Region Environmental Assessment and Monitoring (BREAM) program was established to identify environmental research and monitoring priorities related to future hydrocarbon development activities in the Beaufort Sea and Mackenzie Delta region. The activities occurring during the third year of BREAM focused on major oil spills. Three planning meetings were held: a Project Initiation Meeting and technical meetings of the Community-Based Concerns and Catastrophic Oil Spill Working Groups. The initiation meeting had goals that included identifying specific tasks to be completed by the two Working Groups, discussion of contents and scope of materials being prepared for an oil spill workshop, and determining project schedules. The Community-Based Concerns group focused its work on identifying ecological concerns related to oil spills and their cleanup, identifying community-based ecological issues and concerns, and incorporating local and traditional knowledge into the BREAM program. The group suggested changes to the wording of existing impact hypotheses and oil spill scenarios, and recommended changes in a list of valued ecosystem components. The oil spill group reviewed ecological concerns related to oil spills, and reviewed each oil spill scenario and impact hypothesis selected for an interdisciplinary workshop held in February 1993. The workshop evaluated four of the most important oil spill impact hypotheses (offshore platform blowout, river barge spill of diesel fuel, under-ice spill from a pipeline river crossing, and a pipeline spill affecting mammals). Further research and monitoring related to a number of impact hypotheses was recommended by workshop participants. 57 refs., 29 figs., 12 tabs

  8. Herpetological monitoring and assessment on the Trinity River, Trinity County, California—Final report

    Science.gov (United States)

    Snover, Melissa L.; Adams, Michael J.

    2016-06-14

    The primary goal of the Trinity River Restoration Program is to rehabilitate the fisheries on the dam-controlled Trinity River. However, maintaining and enhancing other wildlife populations through the restoration initiative is also a key objective. Foothill yellow-legged frogs (Rana boylii) and western pond turtles (Actinemys marmorata) have been identified as important herpetological species on which to focus monitoring efforts due to their status as California state-listed species of concern and potential listing on the U.S. Endangered Species List. We developed and implemented a monitoring strategy for these species specific to the Trinity River with the objectives of establishing baseline values for probabilities of site occupancy, colonization, and local extinction; identifying site characteristics that correlate with the probability of extinction; and estimating overall trends in abundance. Our 3-year study suggests that foothill yellow-legged frogs declined in the probability of site occupancy. Conversely, our results suggest that western pond turtles increased in both abundance and the probability of site occupancy. The short length of our study period makes it difficult to draw firm conclusions, but these results provide much-needed baseline data. Further monitoring and directed studies are required to assess how habitat changes and management decisions relate to the status and trend of these species over the long term.

  9. Industrial market assessment of the products of mild gasification: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sinor, J.E.

    1988-01-01

    The goal of this study is to determine the best available conditions, in terms of market volumes and prices, for the products from a mild gasification facility. A process feasibility study will then have to determine the cost of building and operating a facility to make those products. The study is presented as a summary of the options available to a coal producer for creating added product value. For this reason, three specific coal mines owned by AMAX Inc. were chosen, and the options were analyzed from the viewpoint of increasing the total revenue derived from those coals. No specific mild gasification, or mild devolatilization technology was assumed during the assessment. The analysis considers only product prices, volumes, and specifications. It does not assign any intangible value or national benefit to substituting coal for oil or to producing a cleaner fuel. Although it would be desirable to conceive of a product slate which would be immune from energy price fluctuations, such a goal is probably unattainable and no particular emphasis was placed on it. 76 figs., 75 tabs.

  10. Expert judgment in assessing radwaste risks: What Nevadans should know about Yucca Mountain; [Final report

    Energy Technology Data Exchange (ETDEWEB)

    Shrader-Frechette, K. [University of South Florida, Tampa, FL (United States)

    1992-06-01

    For phenomena characterized by accurate and largely complete data, quantitative risk assessment (QRA) provides extraordinarily valuable and objective information. However, with phenomena for which the data, models, or probabilities are incomplete or uncertain, QRA may be less useful and more questionable, because its conclusions are typically empirically and theoretically underdetermined. In the face of empirical or theoretical underdetermination, scientists often are forced to make a number of methodological value judgments and inferences about how to estimate and evaluate the associated risks. The purpose of this project is to evaluate instances of methodological value judgments and invalid or imprecise inferences that have occurred in the QRA done for the proposed Yucca Mountain high-level radioactive waste facility. We shall show (1) that questionable methodological value judgments and inferences have occurred in some Yucca Mountain QRA`S; (2) that questionable judgments and inferences, similar to those in the Yucca Mountain studies, have occurred in previous QRA`s done for other radiation-related facilities and have likely caused earlier QRA`s to err in specific ways; and (3) that, because the value judgments and problems associated with some Yucca Mountain QRA`s include repetitions of similar difficulties in earlier studies, therefore the QRA conclusions of some Yucca Mountain analyses are, at best, uncertain.

  11. Washington wildlife mitigation projects. Final programmatic environmental assessment and finding of no significant impact

    International Nuclear Information System (INIS)

    Bonneville Power Administration (BPA) proposes to fund the portion of the Washington Wildlife Mitigation Agreement (Agreement) pertaining to wildlife habitat mitigation projects to be undertaken in a cooperative effort with the Washington Department of Fish and Wildlife (WDFW). This Agreement serves to establish a monetary budget funded by BPA for projects proposed by Washington Wildlife Coalition members and approved by BPA to protect, mitigate, and improve wildlife and/or wildlife habitat within the State of Washington that has been affected by the construction of Federal dams along the Columbia River. This Environmental Assessment examines the potential environmental effects of acquiring and/or improving wildlife habitat within five different project areas. These project areas are located throughout Grant County and in parts of Okanogan, Douglas, Adams, Franklin, Kittias, Yakima, and Benton Counties. The multiple projects would involve varying combinations of five proposed site-specific activities (habitat improvement, operation and maintenance, monitoring and evaluation, access and recreation management, and cultural resource management). All required Federal, State, and tribal coordination, permits and/or approvals would be obtained prior to ground-disturbing activities

  12. Technology assessment for the advanced life detector. Final technical report, May 1987-January 1988

    Energy Technology Data Exchange (ETDEWEB)

    Burrows, W.D.; George, D.T.

    1988-01-29

    This report summarizes an assessment of technology available to develop a noninvasive life detector for use on the battlefield. The detectors determine if casualties wearing chemical protective overgarments are alive or dead without further exposing either the casualties or the aidmen to the contaminated environment. Seven technology approaches sponsored by the Department of Defense (comprising 11 devices), four technologies identified in a market survey, and one device described in a Broad Agency Announcement proposal were examined as candidate Advanced Life Detectors. The technologies and instruments surveyed included three transmitter-receiver technologies, an electrocardiogram (ECG) technology, pacemaker-transmitter/receiver, dry electrode heart rate monitor, five microwave technologies, flash reflectance oximetry, an ultrasound technology, a streaming potential technology, a dry electrode ECG monitor coupled to a microphone, a statometric technique for determining heart rate and blood pressure, and a vital-signs monitor that determines heart rate and blood pressure using blood pressure cuff and microphones incorporated into the cuff. Analysis of the state-of-the-art of each device indicates that none of them are advanced enough to fulfill all the requirements of the draft Joint Services Operational Requirement. Three of the devices identified are recommended for further evaluation.

  13. Environmental assessment for device assembly facility operations, Nevada Test Site, Nye County, Nevada. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    The U.S. Department of Energy, Nevada Operations Office (DOE/NV), has prepared an environmental assessment (EA), (DOE/EA-0971), to evaluate the impacts of consolidating all nuclear explosive operations at the newly constructed Device Assembly Facility (DAF) in Area 6 of the Nevada Test Site. These operations generally include assembly, disassembly or modification, staging, transportation, testing, maintenance, repair, retrofit, and surveillance. Such operations have previously been conducted at the Nevada Test Site in older facilities located in Area 27. The DAF will provide enhanced capabilities in a state-of-the-art facility for the safe, secure, and efficient handling of high explosives in combination with special nuclear materials (plutonium and highly enriched uranium). Based on the information and analyses in the EA, DOE has determined that the proposed action would not constitute a major federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (42 U.S.C. 4321 et seq.). Therefore, an environmental impact statement is not required, and DOE is issuing this finding of no significant impact.

  14. Washington Wildlife Mitigation Projects : Final Programmatic Environmental Assessment and Finding of No Significant Impact.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration; Washington (State). Dept. of Fish and Wildlife.

    1996-08-01

    Bonneville Power Administration (BPA) proposes to fund the portion of the Washington Wildlife Mitigation Agreement (Agreement) pertaining to wildlife habitat mitigation projects to be undertaken in a cooperative effort with the Washington Department of Fish and Wildlife (WDFW). This Agreement serves to establish a monetary budget funded by BPA for projects proposed by Washington Wildlife Coalition members and approved by BPA to protect, mitigate, and improve wildlife and/or wildlife habitat within the State of Washington that has been affected by the construction of Federal dams along the Columbia River. This Environmental Assessment examines the potential environmental effects of acquiring and/or improving wildlife habitat within five different project areas. These project areas are located throughout Grant County and in parts of Okanogan, Douglas, Adams, Franklin, Kittias, Yakima, and Benton Counties. The multiple projects would involve varying combinations of five proposed site-specific activities (habitat improvement, operation and maintenance, monitoring and evaluation, access and recreation management, and cultural resource management). All required Federal, State, and tribal coordination, permits and/or approvals would be obtained prior to ground-disturbing activities.

  15. Environmental assessment of remedial action at the Lowman Uranium Mill Tailings Site near Lowman, Idaho. Final

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This document assesses the environmental impacts of stabilization on site of the contaminated materials at the Lowman uranium mill tailings site. The Lowman site is 0.5 road mile northeast of the unincorporated village of Lowman, Idaho, and 73 road miles from Boise, Idaho. The Lowman site consists of piles of radioactive sands, an ore storage area, abandoned mill buildings, and windblown/waterborne contaminated areas. A total of 29.5 acres of land are contaminated and most of this land occurs within the 35-acre designated site boundary. The proposed action is to stabilize the tailings and other contaminated materials on the site. A radon barrier would be constructed over the consolidated residual radioactive materials and various erosion control measures would be implemented to ensure the long-term stability of the disposal cell. Radioactive constituents and other hazardous constituents were not detected in the groundwater beneath the Lowman site. The groundwater beneath the disposal cell would not become contaminated during or after remedial action so the maximum concentration limits or background concentrations for the contaminants listed in the draft EPA groundwater protection standards would be met at the point of compliance. No significant impacts were identified as a result of the proposed remedial action at the Lowman site.

  16. Gamma Irradiation Facility at Sandia National Laboratories, Albuquerque, New Mexico. Final environmental assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The US Department of Energy (DOE) has prepared an environmental assessment (EA) on the proposed construction and operation of a new Gamma Irradiation Facility (GIF) at Sandia National Laboratories/New Mexico (SNL/NM). This facility is needed to: enhance capabilities to assure technical excellence in nuclear weapon radiation environments testing, component development, and certification; comply with all applicable ES and H safeguards, standards, policies, and regulations; reduce personnel radiological exposure to comply with ALARA limits in accordance with DOE orders and standards; consolidate major gamma ray sources into a central, secured area; and reduce operational risks associated with operation of the GIF and LICA in their present locations. This proposed action provides for the design, construction, and operation of a new GIF located within TA V and the removal of the existing GIF and Low Intensity Cobalt Array (LICA). The proposed action includes potential demolition of the gamma shield walls and removal of equipment in the existing GIF and LICA. The shielding pool used by the existing GIF will remain as part of the ACRR facility. Transportation of the existing {sup 60}Co sources from the existing LICA and GIF to the new facility is also included in the proposed action. Relocation of the gamma sources to the new GIF will be accomplished by similar techniques to those used to install the sources originally.

  17. Gamma Irradiation Facility at Sandia National Laboratories, Albuquerque, New Mexico. Final environmental assessment

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) has prepared an environmental assessment (EA) on the proposed construction and operation of a new Gamma Irradiation Facility (GIF) at Sandia National Laboratories/New Mexico (SNL/NM). This facility is needed to: enhance capabilities to assure technical excellence in nuclear weapon radiation environments testing, component development, and certification; comply with all applicable ES and H safeguards, standards, policies, and regulations; reduce personnel radiological exposure to comply with ALARA limits in accordance with DOE orders and standards; consolidate major gamma ray sources into a central, secured area; and reduce operational risks associated with operation of the GIF and LICA in their present locations. This proposed action provides for the design, construction, and operation of a new GIF located within TA V and the removal of the existing GIF and Low Intensity Cobalt Array (LICA). The proposed action includes potential demolition of the gamma shield walls and removal of equipment in the existing GIF and LICA. The shielding pool used by the existing GIF will remain as part of the ACRR facility. Transportation of the existing 60Co sources from the existing LICA and GIF to the new facility is also included in the proposed action. Relocation of the gamma sources to the new GIF will be accomplished by similar techniques to those used to install the sources originally

  18. Integrated Ecological River Health Assessments, Based on Water Chemistry, Physical Habitat Quality and Biological Integrity

    Directory of Open Access Journals (Sweden)

    Ji Yoon Kim

    2015-11-01

    Full Text Available This study evaluated integrative river ecosystem health using stressor-based models of physical habitat health, chemical water health, and biological health of fish and identified multiple-stressor indicators influencing the ecosystem health. Integrated health responses (IHRs, based on star-plot approach, were calculated from qualitative habitat evaluation index (QHEI, nutrient pollution index (NPI, and index of biological integrity (IBI in four different longitudinal regions (Groups I–IV. For the calculations of IHRs values, multi-metric QHEI, NPI, and IBI models were developed and their criteria for the diagnosis of the health were determined. The longitudinal patterns of the river were analyzed by a self-organizing map (SOM model and the key major stressors in the river were identified by principal component analysis (PCA. Our model scores of integrated health responses (IHRs suggested that mid-stream and downstream regions were impaired, and the key stressors were closely associated with nutrient enrichment (N and P and organic matter pollutions from domestic wastewater disposal plants and urban sewage. This modeling approach of IHRs may be used as an effective tool for evaluations of integrative ecological river health..

  19. The assessment of the coke wastewater treatment efficacy in rotating biological contractor.

    Science.gov (United States)

    Cema, G; Żabczyński, S; Ziembińska-Buczyńska, A

    2016-01-01

    Coke wastewater is known to be relatively difficult for biological treatment. Nonetheless, biofilm-based systems seem to be promising tool for such treatment. That is why a rotating biological contactor (RBC) system focused on the Anammox process was used in this study. The experiment was divided into two parts with synthetic and then real wastewater. It was proven that it is possible to treat coke wastewater with RBC but such a procedure requires a very long start-up period for the nitritation (190 days), as well as for the Anammox process, where stable nitrogen removal over 70% was achieved after 400 days of experiment. Interestingly, it was possible at a relatively low (20.2 ± 2.2 °C) temperature. The polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) based monitoring of the bacterial community showed that its biodiversity decreased when the real wastewater was treated and it was composed mainly of GC-rich genotypes, probably because of the modeling influence of this wastewater and the genotypes specialization. PMID:26942544

  20. Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications.

    Science.gov (United States)

    Zhang, Wendy Li; Zheng, Ken Yu-Zhong; Zhu, Kevin Yue; Zhan, Janis Ya-Xian; Bi, Cathy Wen-Chuan; Chen, Jian-Ping; Du, Crystal Ying-Qing; Zhao, Kui-Jun; Lau, David Tai-Wai; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung

    2012-08-15

    The commonly used Angelica herbal decoction today is Danggui Buxue Tang (DBT), which is a dietary supplement in treating menopausal irregularity in women, i.e. to nourish "Qi" and to enrich "Blood". According to historical record, many herbal decoctions were also named DBT, but the most popular formulation of DBT was written in Jin dynasty (1247 AD) of China, which contained Astragali Radix (AR) and Angelicae Sinensis Radix (ASR) with a weight ratio of 5:1. However, at least two other Angelica herbal decoctions recorded as DBT were prescribed in Song (1155 AD) and Qing dynasties (1687 AD). Although AR and ASR are still the major components in the DBT herbal decoctions, they are slightly varied in the herb composition. In order to reveal the efficiency of different Angelica herbal decoctions, the chemical and biological properties of three DBT herbal extracts were compared. Significantly, the highest amounts of AR-derived astragaloside III, astragaloside IV, calycosin and formononetin and ASR-derived ferulic acid were found in DBT described in 1247 AD: this preparation showed stronger activities in osteogenic, estrogenic and erythropoetic effects than the other two DBT. The current results supported the difference of three DBT in chemical and biological properties, which could be a result of different herbal combinations. For the first time, this study supports the popularity of DBT described in 1247 AD. PMID:22902230

  1. Wind Resource and Feasibility Assessment Report for the Lummi Reservation

    Energy Technology Data Exchange (ETDEWEB)

    DNV Renewables (USA) Inc.; J.C. Brennan & Associates, Inc.; Hamer Environmental L.P.

    2012-08-31

    This report summarizes the wind resource on the Lummi Indian Reservation (Washington State) and presents the methodology, assumptions, and final results of the wind energy development feasibility assessment, which included an assessment of biological impacts and noise impacts.

  2. Biological effects of static magnetic fields: a selective review with emphasis on risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Easterly, C. E.

    1982-04-01

    Rather than focusing on literature per se, the current study determines the status of magnetic field information that is applicable to risk assessment. Hence, an attempt is made to identify both the literature that is useful to the goal of risk assessment and a framework within which risk assessment methodologies can be derived. From this selected review, it is concluded that three areas exist for which adequate information can be found to begin modelling: disease induction, reproduction and development, and cardiovascular response. The first two are supported by a combination of positive and negative findings and the last by a calculational technique which utilizes the physically well-known principle of flow retardation for a conducting fluid moving through a magnetic field.

  3. Biological effects of static magnetic fields: a selective review with emphasis on risk assessment

    International Nuclear Information System (INIS)

    Rather than focusing on literature per se, the current study determines the status of magnetic field information that is applicable to risk assessment. Hence, an attempt is made to identify both the literature that is useful to the goal of risk assessment and a framework within which risk assessment methodologies can be derived. From this selected review, it is concluded that three areas exist for which adequate information can be found to begin modelling: disease induction, reproduction and development, and cardiovascular response. The first two are supported by a combination of positive and negative findings and the last by a calculational technique which utilizes the physically well-known principle of flow retardation for a conducting fluid moving through a magnetic field

  4. A biological assessment of streams in the eastern United States using a predictive model for macroinvertebrate assemblages

    Science.gov (United States)

    Carlisle, D.M.; Meador, M.R.

    2007-01-01

    A predictive model (RIVPACS-type) for benthic macroinvertebrates was constructed to assess the biological condition of 1,087 streams sampled throughout the eastern United States from 1993-2003 as part of the U.S. Geological Survey's National Water-Quality Assessment Program. A subset of 338 sites was designated as reference quality, 28 of which were withheld from model calibration and used to independently evaluate model precision and accuracy. The ratio of observed (O) to expected (E) taxa richness was used as a continuous measure of biological condition, and sites with O/E values degraded. Spatiotemporal variability of O/E values was evaluated with repeated annual and within-site samples at reference sites. Values of O/E were regressed on a measure of urbanization in three regions and compared among streams in different land-use settings. The model accurately predicted the expected taxa at validation sites with high precision (SD = 0.11). Within-site spatial variability in O/E values was much larger than annual and among-site variation at reference sites and was likely caused by environmental differences among sampled reaches. Values of O/E were significantly correlated with basin road density in the Boston, Massachusetts (p degradation. Taxa that occurred less frequently than predicted by the model were those known to be generally intolerant of a variety of anthropogenic stressors. ?? 2007 American Water Resources Association.

  5. Building channels for transparent risk assessment. Final report RISCOM pilot project

    International Nuclear Information System (INIS)

    Recent developments in the Swedish programme for nuclear waste management have underlined the need for a broad consultation process with public participation. Decision procedures that provide transparency for people outside the groups of experts and political decision-makers must be developed. This report explores what this transparency means and how it could be enhanced. It is acknowledged that the concept of transparency includes three equally important aspects: factual issues, normative issues, and stakeholder''s authenticity. So far experts have dominated the decision process in the nuclear waste area. Value judgements of experts may appear as normative issues, for instance among other scientists; or they may be related to issues of authenticity, for instance when discussions take place with community stakeholders. The formal decision process must always be the basis for building transparency. Two dominant approaches are compared: the Swedish ''review/decide'' approach, and the ''inquiry/decide'' approach used in the UK. Suggestions are made as to how the best features of the two approaches could be combined. The report also includes a study on the systemic roles of SKI/SSI in the Swedish nuclear waste management system. This study identifies several systemic functions carried out by SKI/SSI. Awareness of these roles within SKI and SSI (and among other stakeholders) is crucial for transparency. This report argues that a key element in building transparency is to create mechanisms for ''stretching'' SKB. Various channels for stretching and providing new perspectives are explored. Among the procedures discussed are those concerned with hearings and dialogue. Environmental Impact Assessment (EIA) is seen as the umbrella under which most of the stretching activities can take place. Team Syntegrity was used as a method to compare the Swedish and UK procedures. It is a non-hierarchical approach that enhances the effective contribution of a wide variety of

  6. Final Report - Assessment of Potential Phosphate Ion-Cementitious Materials Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Naus, Dan J [ORNL; Mattus, Catherine H [ORNL; Dole, Leslie Robert [ORNL

    2007-06-01

    The objectives of this limited study were to: (1) review the potential for degradation of cementitious materials due to exposure to high concentrations of phosphate ions; (2) provide an improved understanding of any significant factors that may lead to a requirement to establish exposure limits for concrete structures exposed to soils or ground waters containing high levels of phosphate ions; (3) recommend, as appropriate, whether a limitation on phosphate ion concentration in soils or ground water is required to avoid degradation of concrete structures; and (4) provide a "primer" on factors that can affect the durability of concrete materials and structures in nuclear power plants. An assessment of the potential effects of phosphate ions on cementitious materials was made through a review of the literature, contacts with concrete research personnel, and conduct of a "bench-scale" laboratory investigation. Results of these activities indicate that: no harmful interactions occur between phosphates and cementitious materials unless phosphates are present in the form of phosphoric acid; phosphates have been incorporated into concrete as set retarders, and phosphate cements have been used for infrastructure repair; no standards or guidelines exist pertaining to applications of reinforced concrete structures in high-phosphate environments; interactions of phosphate ions and cementitious materials has not been a concern of the research community; and laboratory results indicate similar performance of specimens cured in phosphate solutions and those cured in a calcium hydroxide solution after exposure periods of up to eighteen months. Relative to the "primer," a separate NUREG report has been prepared that provides a review of pertinent factors that can affect the durability of nuclear power plant reinforced concrete structures.

  7. Assessment of the potential of solar thermal small power systems in small utilities. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Steitz, P.; Mayo, L.G.; Perkins, S.P. Jr.

    1978-11-01

    This study involved an assessment of the potential economic benefit of small solar thermal electric power systems to small municipal and rural electric utilities. Five different solar thermal small power system configurations were considered in the study representing three different solar thermal technologies. The configurations included: (1) 1-MW, 2-MW, and 10-MW parabolic dish concentrators with a 15-kW heat engine mounted at the focal point of each dish. These systems utilized advanced battery energy storage. (2) A 10-MW system with variable slat concentrators and central steam Rankine energy conversion. This system utilized sensible thermal energy storage. (3) A 50-MW central receiver system consisting of a field of heliostats concentrating energy on a tower-mounted receiver and a central steam Rankine conversion system. This system also utilized sensible thermal storage. The approach used in determining the potential for solar thermal small power systems in the small utility market involved a comparison of the economics of power supply expansion plans for seven hypothetical small utilities through the year 2000 both with and without the solar thermal small power systems. Insolation typical of the Southwestern US was assumed. A comparison of the break-even capital costs with the range of plant costs estimated in this study yields the following conclusions: (1) The parabolic dish concentrator systems could be economically competitive with conventional generation if the lowest capital costs can be achieved. (2) The variable slat concentrator and central receiver systems would have to achieve lower costs than the lowest in the cost ranges generally assumed in the study to become economically competitive. (3) All of the solar thermal plant types are potentially more competitive in utilities which are heavily dependent upon oil.

  8. Integrated Dry NOx/SO2 Emissions Control System, A DOE Assessment; FINAL

    International Nuclear Information System (INIS)

    The goal of the U.S. Department of Energy's (DOE) Clean Coal Technology (CCT) Program is to furnish the energy marketplace with a number of advanced, more efficient, and environmentally responsible coal utilization technologies through demonstration projects. These projects seek to establish the commercial feasibility of the most promising advanced coal technologies that have developed beyond the proof-of-concept stage. This document serves as a DOE post-project assessment (PPA) of a project selected in CCT Round III, the Integrated Dry NO(sub x)/SO(sub 2) Emissions Control System (IDECS), as described in a Report to Congress (U.S. Department of Energy 1991). The desire to reduce emissions of nitrogen oxides (NO, nitric oxide, and NO(sub 2), nitrogen dioxide, collectively referred to as NO(sub x)) and sulfur dioxide (SO(sub 2)) by up to 70 percent at a minimum capital expenditure, while limiting waste production to dry solids that can be handled by conventional ash-removal equipment, prompted Public Service Company of Colorado (PSCC) to submit the proposal for the IDECS project. In March 1991, PSCC entered into a cooperative agreement with DOE to conduct the study. The project was sited at PSCC's Arapahoe Steam Electric Generating Station in Denver, Colorado. The purpose of this CCT project was to demonstrate the reduction of NO(sub x) and SO(sub 2) emissions by installing a combination of existing and emerging technologies, which were expected to work synergistically to reduce emissions. The technologies were low-NO(sub x) burners (LNBS), overfire air (OFA), and selective noncatalytic reduction (SNCR) for NO(sub x) reduction; and dry sorbent injection (DSI), both with and without flue-gas humidification (FGH), for SO(sub 2) reduction. DOE provided 50 percent of the total project funding of$26.2 million

  9. Final Radiological Assessment of External Exposure for CLEAR-Line Americium Recovery Operations

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Adam C. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Belooussova, Olga N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hetrick, Lucas Duane [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-11-12

    Los Alamos National Laboratory is currently planning to implement an americium recovery program. The americium, ordinarily isotopically pure 241Am, would be extracted from existing Pu materials, converted to an oxide and shipped to support fabrication of americium oxide-beryllium neutron sources. These operations would occur in the currently proposed Chloride Extraction and Actinide Recovery (CLEAR) line of glove boxes. This glove box line would be collocated with the currently-operational Experimental Chloride Extraction Line (EXCEL). The focus of this document is to provide an in-depth assessment of the currently planned radiation protection measures and to determine whether or not further design work is required to satisfy design-goal and ALARA requirements. Further, this document presents a history of americium recovery operations in the Department of Energy and high-level descriptions of the CLEAR line operations to provide a basis of comparison. Under the working assumptions adopted by this study, it was found that the evaluated design appears to mitigate doses to a level that satisfies the ALARA-in-design requirements of 10 CFR 835 as implemented by the Los Alamos National Laboratory procedure P121. The analyses indicate that extremity doses would also meet design requirements. Dose-rate calculations were performed using the radiation transport code MCNP5 and doses were estimated using a time-motion study developed in consort with the subject matter expert. A copy of this report and all supporting documentation are located on the Radiological Engineering server at Y:\\Rad Engineering\\2013 PROJECTS\\TA-55 Clear Line.

  10. The impact of formative assessment techniques on the instruction of the high school biology units of photosynthesis and cellular respiration

    Science.gov (United States)

    Tury, Shanna Fawn

    The effect of formative assessment on student learning during student-centered, inquiry-based instruction was studied in a high school biology class. The objective of this study was to test whether increasing the level of formative assessment, including feedback to students and reflection on laboratory activities, would make an impact on the learning of concepts related to cellular metabolism, such as cellular respiration and photosynthesis. Two units of instruction were evaluated, one utilizing active learning strategies along with formative assessment techniques, and the other taught in a more teacher-centered manner. The revised methodology showed a statistically significant increase in student learning gains as compared to the unimproved technique. The increased amount of hands-on activities for students, observation of students in an informal context, student and teacher interaction, immediate feedback to students, public discussion and reflection on lab activities and results, and modification of instruction by the teacher is implicated in the trend found in these data. The results suggest that the combined effect of active, inquiry-based instruction and a variety of formative assessments can have a significant positive effect on student learning of topics related to cellular metabolism, such as photosynthesis and cellular respiration.

  11. Minimal analytical characterization of engineered nanomaterials needed for hazard assessment in biological matrices

    NARCIS (Netherlands)

    Bouwmeester, H.; Lynch, I.; Marvin, H.J.P.; Dawson, K.A.; Berges, M.; Braguer, D.; Byrne, H.J.; Casey, A.; Chambers, G.; Clift, M.J.D.; Elia, G.; Fernandes, T.F.; fjellsbo, L.B.; Hatto, P.; Juillerat, L.; Klein, C.; Kreyling, W.G.; Nickel, C.; Riediker, M.; Stone, V.

    2011-01-01

    This paper presents the outcomes from a workshop of the European Network on the Health and Environmental Impact of Nanomaterials (NanoImpactNet). During the workshop, 45 experts in the field of safety assessment of engineered nanomaterials addressed the need to systematically study sets of engineere

  12. Eastern Baltic cod in distress: biological changes and challenges for stock assessment

    DEFF Research Database (Denmark)

    Eero, Margit; Hjelm, Joakim; Behrens, Jane;

    2015-01-01

    The eastern Baltic (EB) cod (Gadus morhua) stock was depleted and overexploited for decades until the mid-2000s, when fishing mortality rapidly declined and biomass started to increase, as shown by stock assessments. These positive developments were partly assigned to effective management measure...

  13. Assessing the Attitudes and Beliefs of Preservice Middle School Science Teachers toward Biologically Diverse Animals

    Science.gov (United States)

    Wagler, Ron; Wagler, Amy

    2015-01-01

    The purpose of this study was to assess the relationship between United States (US) preservice middle school science teacher characteristics, their attitude toward a specific animal and their belief concerning the likelihood of incorporating information about that specific animal into their future science classroom. The study participants…

  14. 76 FR 3076 - Availability of an Environmental Assessment for a Biological Control Agent for Air Potato

    Science.gov (United States)

    2011-01-19

    ... Control Agent for Air Potato AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice of... Inspection Service has prepared an environmental assessment (EA) relative to the control of air potato... severity of air potato infestations. We are making the EA available to the public for review and...

  15. Final report on the safety assessment of Arnica montana extract and Arnica montana.

    Science.gov (United States)

    2001-01-01

    ingredient group can be extrapolated to another in the group, or to the same ingredient extracted differently, these data were not considered sufficient to assess the safety of these ingredients. Additional data needs include current concentration of use data; function in cosmetics; ultraviolet (UV) absorption data-if absorption occurs in the UVA or UVB range, photosensitization data are needed; gross pathology and histopathology in skin and other major organ systems associated with repeated dermal exposures; dermal reproductive/developmental toxicity data; inhalation toxicity data, especially addressing the concentration, amount delivered, and particle size; and genotoxicity testing in a mammalian system; if positive, a 2-year dermal carcinogenicity assay performed using National Toxicology Program (NTP) methods is needed. Until these data are available, it is concluded that the available data are insufficient to support the safety of these ingredients in cosmetic formulations.

  16. Building channels for transparent risk assessment. Final report RISCOM pilot project

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Kjell [Karinta-Konsult, Taeby (Sweden); Espejo, R. [Syncho Ltd, Birmingham (United Kingdom); Wene, C.O. [Profu AB, Lund (Sweden)

    1998-01-01

    Recent developments in the Swedish programme for nuclear waste management have underlined the need for a broad consultation process with public participation. Decision procedures that provide transparency for people outside the groups of experts and political decision-makers must be developed. This report explores what this transparency means and how it could be enhanced. It is acknowledged that the concept of transparency includes three equally important aspects: factual issues, normative issues, and stakeholder``s authenticity. So far experts have dominated the decision process in the nuclear waste area. Value judgements of experts may appear as normative issues, for instance among other scientists; or they may be related to issues of authenticity, for instance when discussions take place with community stakeholders. The formal decision process must always be the basis for building transparency. Two dominant approaches are compared: the Swedish ``review/decide`` approach, and the ``inquiry/decide`` approach used in the UK. Suggestions are made as to how the best features of the two approaches could be combined. The report also includes a study on the systemic roles of SKI/SSI in the Swedish nuclear waste management system. This study identifies several systemic functions carried out by SKI/SSI. Awareness of these roles within SKI and SSI (and among other stakeholders) is crucial for transparency. This report argues that a key element in building transparency is to create mechanisms for ``stretching`` SKB. Various channels for stretching and providing new perspectives are explored. Among the procedures discussed are those concerned with hearings and dialogue. Environmental Impact Assessment (EIA) is seen as the umbrella under which most of the stretching activities can take place. Team Syntegrity was used as a method to compare the Swedish and UK procedures. It is a non-hierarchical approach that enhances the effective contribution of a wide variety of

  17. Method for assessing the impact of emission gasses on physiology and productivity in biological methanogenesis.

    Science.gov (United States)

    Seifert, A H; Rittmann, S; Bernacchi, S; Herwig, C

    2013-05-01

    This contribution presents a method for quantification of the impact of emission gasses on the methane production with hydrogenotrophic methanogenic archaea. The developed method allows a robust quantification of the influence of real gasses on the volumetric productivity of methanogenic cultures by uncoupling physiological and mass transfer effects. This is achieved over reference experiments with pure H2 and CO2, simulating the mass transfer influence of the non-convertible side components by addition of N2 to the reactant stream. Furthermore, this method was used to examine the performance of Methanothermobacter marburgensis on different emission gasses. None of the present side components had a negative effect on the volumetric methane production rate. The presented method showed to be ready to use as a generic tool for feasibility studies and quantification of the physiological impact regarding the use of exhaust gasses as reactant gas for the biological methanogenesis. PMID:23582218

  18. Assessment of the differential linear coherent scattering coefficient of biological samples

    Science.gov (United States)

    Conceição, A. L. C.; Antoniassi, M.; Poletti, M. E.

    2010-07-01

    New differential linear coherent scattering coefficient, μ CS, data for four biological tissue types (fat pork, tendon chicken, adipose and fibroglandular human breast tissues) covering a large momentum transfer interval (0.07≤ q≤70.5 nm -1), resulted from combining WAXS and SAXS data, are presented in order to emphasize the need to update the default data-base by including the molecular interference and the large-scale arrangements effect. The results showed that the differential linear coherent scattering coefficient demonstrates influence of the large-scale arrangement, mainly due to collagen fibrils for tendon chicken and fibroglandular breast samples, and triacylglycerides for fat pork and adipose breast samples at low momentum transfer region. While, at high momentum transfer, the μ CS reflects effects of molecular interference related to water for tendon chicken and fibroglandular samples and, fatty acids for fat pork and adipose samples.

  19. Assessment of the differential linear coherent scattering coefficient of biological samples

    Energy Technology Data Exchange (ETDEWEB)

    Conceicao, A.L.C.; Antoniassi, M. [Departamento de Fisica e Matematica, FFCLRP, Universidade de Sao Paulo, Ribeirao Preto, 14040-901 Sao Paulo (Brazil); Poletti, M.E., E-mail: poletti@ffclrp.usp.b [Departamento de Fisica e Matematica, FFCLRP, Universidade de Sao Paulo, Ribeirao Preto, 14040-901 Sao Paulo (Brazil)

    2010-07-21

    New differential linear coherent scattering coefficient, {mu}{sub CS}, data for four biological tissue types (fat pork, tendon chicken, adipose and fibroglandular human breast tissues) covering a large momentum transfer interval (0.07{<=}q{<=}70.5 nm{sup -1}), resulted from combining WAXS and SAXS data, are presented in order to emphasize the need to update the default data-base by including the molecular interference and the large-scale arrangements effect. The results showed that the differential linear coherent scattering coefficient demonstrates influence of the large-scale arrangement, mainly due to collagen fibrils for tendon chicken and fibroglandular breast samples, and triacylglycerides for fat pork and adipose breast samples at low momentum transfer region. While, at high momentum transfer, the {mu}{sub CS} reflects effects of molecular interference related to water for tendon chicken and fibroglandular samples and, fatty acids for fat pork and adipose samples.

  20. Estimation of the Biological Methods of Assessing Soil N-Supplying Capacity in Calcareous Soil

    Institute of Scientific and Technical Information of China (English)

    JIN Fa-hui; LI Shi-qing; LU Hong-ling; LI Sheng-xiu

    2007-01-01

    Although many biological methods are used to determine soil nitrogen supplying capacity, there are certain differences in the results for different types of soils and various ways of measurement due to the complexity of soil N conformation, the high variance of soil and microorganism, and the difference of environment. Therefore, it is not clear about which biologic incubation method is better for calcareous soil. In this study, pot experiments were performed by using 25 different calcareous surface soil samples on the Loess Plateau and taking the N uptake of wheat and corn with leaching soil initial nitrate and without leaching in pot experiments as the control to investigate the difference of eight biological incubation methods for reflecting soil nitrogen supply capacity. The eight biological methods are waterlogged incubation, aerobic incubation for 2 weeks and for 4 weeks, dry-wet alternation aerobic incubation for 2 weeks, long-term alternate leaching aerobic incubation (and N mineralization potential, N0), short-term leaching aerobic incubation, microbial biomass carbon (BC), and microbial biomass nitrogen (BN) method, respectively. Among these methods, the dry-wet alternation aerobic incubation and aerobic incubation for 4 weeks were the modification of the method of aerobic incubation for 2 weeks according to the actual farmland moisture. The results showed that the correlation coefficients between these methods and crop uptake N with leaching soil initial nitrate were 0.530, 0.700, 0.777, 0.768, 0.764 (and 0.790, N0), 0.650, 0.555, and 0.465, respectively (r0.05 = 0.369, r0.01 = 0.505). While without leaching soil initial nitrate, their coefficients were 0.351, 0.963, 0.962, 0.959, 0.825 (and 0.812, N0), 0.963, 0.289, and 0.095, respectively (r0.05=0.369, r0.01 =0.505). In conclusion,excluding the soil initial nitrate, the correlation coefficients between the eight methods and crop uptake N were, from high to low, N0, aerobic incubation for 4 weeks, dry

  1. Biological Assessment of the Advanced Turbine Design at Wanapum Dam, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Dauble, Dennis D.; Deng, Zhiqun; Richmond, Marshall C.; Moursund, Russell A.; Carlson, Thomas J.; Rakowski, Cynthia L.; Duncan, Joanne P.

    2007-09-12

    This report summarizes the results of studies sponsored by the U.S. Department of Energy and conducted by Pacific Northwest National Laboratory to evaluate the biological performance (likelihood of injury to fish) from an advanced design turbine installed at Unit 8 of Wanapum Dam on the Columbia River in Washington State in 2005. PNNL studies included a novel dye technique to measure injury to juvenile fish in the field, an evaluation of blade-strike using both deterministic and stochastic models, and extended analysis of the response of the Sensor Fish Device to strike, pressure, and turbulence within the turbine system. Fluorescein dye was used to evaluate injuries to live fish passed through the advanced turbine and an existing turbine at two spill discharges (15 and 17 kcfs). Under most treatments the results were not significantly different for the two turbines, however, eye injury occurred in nearly 30% of fish passing through Unit 9 but in less than 10% of those passing through Unit 8 at 15 kcfs. Both deterministic and stochastic blade-strike models were applied for the original and new AHTS turbines. The modeled probabilities were compared to the Sensor Fish results (Carlson et al. 2006) and the biological studies using juvenile fish (Normandeau et al. 2005) under the same operational parameters. The new AHTS turbine had slightly higher modeled injury rates than the original turbine, but no statistical evidence to suggest that there is significant difference in blade-strike injury probabilities between the two turbines, which is consistent with the experiment results using Sensor Fish and juvenile fish. PNNL also conducted Sensor Fish studies at Wanapum Dam in 2005 concurrent with live fish studies. The probablility of severe collision events was similar for both turbine. The advanced turbine had a slightly lower probability of severe shear events but a slightly higher probability of slight shear.

  2. Biosphere modelling for dose assessments of radioactive waste repositories. Final report

    International Nuclear Information System (INIS)

    The aims of the Complementary Studies Working Group were: to investigate and explain differences which exist between contemporary models with respect to how, for a given test case, they represent the modelled Features, Events and Processes (FEPs) and how the nature of these representations affects the calculational end-points; to determine the most appropriate ways of representing key FEPs; to identify where knowledge needs to be improved to give better representations of these key FEPs in the future and where simplifications of existing formulations might be possible; to show that the modelling undertaken is suitable for purpose, in that it is robust and that it is unlikely that the radiological consequences calculated by the models would be underestimated (so that any conservative bias in the models is justified); to build confidence in the available modelling tools; to extend the work undertaken in the first phase of BIOMOVS to include consideration of radiological dose. Ten modelling groups from Western Europe and Canada have participated, revealing a variety of representations of radionuclide transport processes and techniques for calculating dose. The exercise has focused on the ways in which key FEPs are represented with the intention of determining the robustness or otherwise of existing representations. This has been achieved by applying a well defined dataset representative of a Central European inland valley. Human habits and lifestyle are chosen to be representative of a subsistence agricultural community. Climatic conditions are those of the present day. Many of the conclusions have relevance beyond the immediate concerns of the Central European biospheres and, although care should be exercised when terms of reference differ greatly from the system detailed here, much has been learned which has wider applicability. The exercise has successfully compared not only the behaviour of biosphere models for waste disposal assessments, but has also provided the

  3. Burlington Bottoms Wildlife Mitigation Project. Final Environmental Assessment/Management Plan and Finding of No Significant Impact.

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-01

    Bonneville Power Administration (BPA) proposes to fund wildlife management and enhancement activities for the Burlington bottoms wetlands mitigation site. Acquired by BPA in 1991, wildlife habitat at Burlington bottoms would contribute toward the goal of mitigation for wildlife losses and inundation of wildlife habitat due to the construction of Federal dams in the lower Columbia and Willamette River Basins. Target wildlife species identified for mitigation purposes are yellow warbler, great blue heron, black-capped chickadee, red-tailed hawk, valley quail, spotted sandpiper, wood duck, and beaver. The Draft Management Plan/Environmental Assessment (EA) describes alternatives for managing the Burlington Bottoms area, and evaluates the potential environmental impacts of the alternatives. Included in the Draft Management Plan/EA is an implementation schedule, and a monitoring and evaluation program, both of which are subject to further review pending determination of final ownership of the Burlington Bottoms property.

  4. Burlington Bottoms Wildlife Mitigation Project. Final environmental assessment/management plan and finding of no significant impact

    International Nuclear Information System (INIS)

    Bonneville Power Administration (BPA) proposes to fund wildlife management and enhancement activities for the Burlington bottoms wetlands mitigation site. Acquired by BPA in 1991, wildlife habitat at Burlington bottoms would contribute toward the goal of mitigation for wildlife losses and inundation of wildlife habitat due to the construction of Federal dams in the lower Columbia and Willamette River Basins. Target wildlife species identified for mitigation purposes are yellow warbler, great blue heron, black-capped chickadee, red-tailed hawk, valley quail, spotted sandpiper, wood duck, and beaver. The Draft Management Plan/Environmental Assessment (EA) describes alternatives for managing the Burlington Bottoms area, and evaluates the potential environmental impacts of the alternatives. Included in the Draft Management Plan/EA is an implementation schedule, and a monitoring and evaluation program, both of which are subject to further review pending determination of final ownership of the Burlington Bottoms property

  5. Evaluative studies in nuclear medicine research: positron computed tomography assessment. Final report, January 1, 1982-December 31, 1982

    International Nuclear Information System (INIS)

    Results are reported of the final phase of the study effort generally titled Evaluative Studies in Nuclear Medicine Research. The previous work is reviewed and extended to an assessment providing perspectives on medical applications of positron emission tomographic (PET) systems, their technological context, and the related economic and marketing environment. Methodologies developed and used in earlier phases of the study were continued, but specifically extended to include solicitation of opinion from commercial organizations deemed to be potential developers, manufacturers and marketers of PET systems. Several factors which influence the demand for clinical uses of PET are evaluated and discussed. The recent Federal funding of applied research with PET systems is found to be a necessary and encouraging event toward a determination that PET either is a powerful research tool limited to research, or whether it also presents major clinical utility. A comprehensive, updated bibliography of current literature related to the development, applications and economic considerations of PET technology is appended

  6. ALINET: a model for assessing energy conservation opportunities in the food processing industry. Final technical report, September 1977-December 1979

    Energy Technology Data Exchange (ETDEWEB)

    Levis, A H; Ducot, E R; Levis, I S; Webster, T F

    1979-12-01

    ALINET is a network model designed for the analysis of energy use in the food processing and distribution sector and for the evaluation of the potential effectiveness of energy conserving technologies. The conceptual framework of the model, as well as the design and implementation of the computer software are described. The wheat system at the national, state, and facility-specific level is used to illustrate the model's operation and use. A pilot project, carried out in cooperation with industry, is described in which energy use in (a) hard wheat milling, and (b) durum milling and pasta manufacture is analyzed. Finally, the introduction of an alternative technology for pasta drying is assessed in terms of energy conservation and cost. Recommendation for further applications and institutionalization of the model are made.

  7. Projection of Environmental Pollutant Emissions From Different Final Waste Disposal Methods Based on Life Cycle Assessment Studies in Qazvin City

    Directory of Open Access Journals (Sweden)

    Javad Torkashvand

    2015-12-01

    Full Text Available In the current study, the life cycle assessment (LCA method was used to expect the emissions of different environmental pollutants through qualitative and quantitative analyses of solid wastes of Qazvin city in different final disposal methods. Therefore, four scenarios with the following properties considering physical analysis of Qazvin’s solid wastes, the current status of solid waste management in Iran, as well as the future of solid waste management of Qazvin were described. In order to detect the quantity of the solid wastes, the volume-weighted analysis was used and random sampling method was used for physical analysis. Of course, regarding the method of LCA, it contains all stages from solid wastes generation to its disposal. However, since the main aim of this study was final disposal stage, the emissions of pollutants of these stages were ignored. Next, considering the mixture of the solid waste, the amount of pollution stemming from each of final disposal methods from other cities having similar conditions was estimated. The findings of the study showed that weight combination of Qazvin solid wastes is entirely similar to that of other cities. Thus, the results of this study can be applied by decision makers around the country. In scenarios 1 and 2, emission of leachate containing high amounts of COD and BOD is high and also the highest content of nitrate, which can contaminate water and soil resulting in high costs for their management. In scenarios 3 and 4, the amounts of gaseous pollutants, particularly CO2, as well as nitrogen oxides are very high. In conclusion, the LCA methods can effectively contribute to the management of municipal solid wastes (MSW to control environmental pollutants with least expenses.

  8. An Analysis of the Content, Policies and Assessment of ICT Curricula in the Final Years of Secondary Schooling in Australia and Vietnam: A Comparative Educational Study

    Science.gov (United States)

    Tran, Thang Manh; Stoilescu, Dorian

    2016-01-01

    This paper explores and analyses similarities and differences in ICT curricula, policies, and assessment between the Vietnamese and Australian educational systems for the final years of secondary educational level. It was found that while having a common core set of tendencies, the Australian ICT curricula, policies, and assessments differ…

  9. Biosphere modelling for dose assessments of radioactive waste repositories. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Klos, R. [Paul Scherrer Inst., Wuerenlingen (Switzerland)] [and others

    1996-09-01

    The aims of the Complementary Studies Working Group were: to investigate and explain differences which exist between contemporary models with respect to how, for a given test case, they represent the modelled Features, Events and Processes (FEPs) and how the nature of these representations affects the calculational end-points; to determine the most appropriate ways of representing key FEPs; to identify where knowledge needs to be improved to give better representations of these key FEPs in the future and where simplifications of existing formulations might be possible; to show that the modelling undertaken is suitable for purpose, in that it is robust and that it is unlikely that the radiological consequences calculated by the models would be underestimated (so that any conservative bias in the models is justified); to build confidence in the available modelling tools; to extend the work undertaken in the first phase of BIOMOVS to include consideration of radiological dose. Ten modelling groups from Western Europe and Canada have participated, revealing a variety of representations of radionuclide transport processes and techniques for calculating dose. The exercise has focused on the ways in which key FEPs are represented with the intention of determining the robustness or otherwise of existing representations. This has been achieved by applying a well defined dataset representative of a Central European inland valley. Human habits and lifestyle are chosen to be representative of a subsistence agricultural community. Climatic conditions are those of the present day. Many of the conclusions have relevance beyond the immediate concerns of the Central European biospheres and, although care should be exercised when terms of reference differ greatly from the system detailed here, much has been learned which has wider applicability. The exercise has successfully compared not only the behaviour of biosphere models for waste disposal assessments, but has also provided the

  10. Validation of a Fecal Glucocorticoid Assay to Assess Adrenocortical Activity in Meerkats Using Physiological and Biological Stimuli.

    Directory of Open Access Journals (Sweden)

    Ines Braga Goncalves

    Full Text Available In mammals, glucocorticoid (i.e. GC levels have been associated with specific life-history stages and transitions, reproductive strategies, and a plethora of behaviors. Assessment of adrenocortical activity via measurement of glucocorticoid metabolites in feces (FGCM has greatly facilitated data collection from wild animals, due to its non-invasive nature, and thus has become an established tool in behavioral ecology and conservation biology. The aim of our study was to validate a fecal glucocorticoid assay for assessing adrenocortical activity in meerkats (Suricata suricatta, by comparing the suitability of three GC enzyme immunoassays (corticosterone, 11β-hydroxyetiocholanolone and 11oxo-etiocholanolone in detecting FGCM increases in adult males and females following a pharmacological challenge with adrenocorticotropic hormone (ACTH and biological stimuli. In addition, we investigated the time course characterizing FGCM excretion, the effect of age, sex and time of day on FGCM levels and assessed the potential effects of soil contamination (sand on FGCM patterns. Our results show that the group specific 11β-hydroxyetiocholanolone assay was most sensitive to FGCM alterations, detecting significant and most distinctive elevations in FGCM levels around 25 h after ACTH administration. We found no age and sex differences in basal FGCM or on peak response levels to ACTH, but a marked diurnal pattern, with FGCM levels being substantially higher in the morning than later during the day. Soil contamination did not significantly affect FGCM patterns. Our results emphasize the importance of conducting assay validations to characterize species-specific endocrine excretion patterns, a crucial step to all animal endocrinology studies using a non-invasive approach.

  11. Central Colorado Assessment Project - Application of integrated geologic, geochemical, biologic, and mineral resource studies

    Science.gov (United States)

    Klein, T.L.; Church, S.E.; Caine, J.S.; Schmidt, T.S.; deWitt, E.H.

    2008-01-01

    Central Colorado is one of the fastest-growing regions in the Western United States. Population along the Front Range increased more than 30 percent between 1990 and 2000 (http://www.demographia.com/db-metro3newworld.htm) with some counties within the study area, such as Park County, experiencing greater than 100-percent growth (http://www.censusscope.org/us/s8/rank_popl_growth.html). This growth has caused tremendous demand for natural resources and has created challenging land-management issues related to the interface between wilderness and urban expansion. Management of this wilderness/urban interface will benefit from current digital geoscience information collected by the U.S. Geological Survey (USGS) Central Colorado Assessment Project that began in 2003. Approximately 20,800 square miles (53,800 km2) of land divided almost equally between the public and private sectors were part of the assessment.

  12. Deriving acceptable biological catch from the overfishing limit: implications for assessment models

    OpenAIRE

    Prager, Michael H.; Shertzer, Kyle W.

    2010-01-01

    The recently revised Magnuson–Stevens Fishery Conservation and Management Act requires that U.S. fishery management councils avoid overfishing by setting annual catch limits (ACLs) not exceeding recommendations of the councils’ scientific advisers. To meet that requirement, the scientific advisers will need to know the overfishing limit (OFL) estimated in each stock assessment, with OFL being the catch available from applying the limit fishing mortality rate to current or projected stock b...

  13. Instream biological assessment of NPDES point source discharges at the Savannah River Site, 1997-1998

    Energy Technology Data Exchange (ETDEWEB)

    Specht, W.L.

    2000-02-28

    The Savannah River Site currently has 33 permitted NPDES outfalls that have been permitted by the South Carolina Department of Health an Environmental Control to discharge to SRS streams and the Savannah River. In order to determine the cumulative impacts of these discharges to the receiving streams, a study plan was developed to perform in-stream assessments of the fish assemblages, macroinvertebrate assemblages, and habitats of the receiving streams.

  14. Instream biological assessment of NPDES point source discharges at the Savannah River Site, 1997-1998

    International Nuclear Information System (INIS)

    The Savannah River Site currently has 33 permitted NPDES outfalls that have been permitted by the South Carolina Department of Health an Environmental Control to discharge to SRS streams and the Savannah River. In order to determine the cumulative impacts of these discharges to the receiving streams, a study plan was developed to perform in-stream assessments of the fish assemblages, macroinvertebrate assemblages, and habitats of the receiving streams

  15. Chemical and biological risk assessment of chronic exposure to PAH contaminated sediments

    Energy Technology Data Exchange (ETDEWEB)

    Means, J.; McMillin, D.; Kondapi, N. [Louisiana State Univ., Baton Rouge, LA (United States)

    1995-12-31

    Chronically contaminated sediments represent a long-term source of mixtures of contaminants, exposing aquatic ecosystems to PAH through desorption and bioaccumulation. Chronic toxicity assessments must address potential of these bond contaminants. Environmental impacts and ecological health hazards of sediment-bound normal, alkylated and heterocyclic aromatic hydrocarbons are functions of their entry into aquatic food webs and are controlled by both abiotic and biotic factors. Laboratory and field microcosm exposures of fish and invertebrates were conducted followed by assessments of effects using chemical analysis and biomarkers of potential genotoxic effects. Chemical analysis of accumulated residues of 62 individual PAH were conducted in oysters, Crassostrea virginica exposed to PAH contaminated sediments in the field. The rates and equilibrium bioaccumulation constants for each were determined. Fish were exposed to the same contaminated sediments in laboratory and field exposures. Measurements of ethoxy-resorufin-o-deethylase activity induction as well as alterations in the expression of the p53 tumor suppressor gene were performed on exposed fish liver samples. EROD activities were increased significantly relative to unexposed and laboratory/field control sediment-exposed fish, however, the responses of individuals were highly variable. Fundulus grandis or Gambusia affinis, exposed to contaminated sediments in the laboratory, revealed changes in the expression of the p53 tumor suppressor gene. The degree to which mutations within the gene occurred was assessed using PCR followed by measurement of single stranded DNA polymorphisms using gel electrophoresis chromatography.

  16. An Evaluation of Two Different Methods of Assessing Independent Investigations in an Operational Pre-University Level Examination in Biology in England.

    Science.gov (United States)

    Brown, Chris

    1998-01-01

    Explored aspects of assessment of extended investigation ("project") practiced in the operational examinations of The University of Cambridge Local Examinations Syndicate (UCLES) for the perspective of construct validity. Samples of the 1993 (n=333) and 1996 (n=259) biology test results reveal two methods of assessing the project. (MAK)

  17. Direct heat applications of geothermal energy in The Geysers/Clear Lake region. Volume I. Geotechnical assessment, agribusiness applications, socioeconomic assessment, engineering assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1976-08-01

    Discussion is presented under the following section headings: background and some technical characteristics of geothermal resources; geology and geohydrology, geophysics, and, conclusions regarding availability of geothermal energy for nonelectric uses; agricultural assessment of Lake County, site assessment for potential agricultural development, analysis of potential agricultural applications, special application of low cost geothermal energy to algae harvesting, development of an integrated agribusiness, geothermal complex in Lake County, analysis of individual enterprises, and, recommendations for subsequent work; demographic characteristics, economic condition and perspective of Lake County, economic impact of geothermal in Lake County, social and economic factors related to geothermal resource development, socioeconomic impact of nonelectric uses of geothermal energy, and, identification of direct heat applications of geothermal energy for Lake County based on selected interviews; cost estimate procedure, example, justification of procedure, and, typical costs and conclusions; and, recommended prefeasibility and feasibility studies related to construction of facilities for nonelectric applications of geothermal resource utilization. (JGB)

  18. Assessing Soil Biological Properties of Natural and Planted Forests in the Malaysian Tropical Lowland Dipterocarp Forest

    Directory of Open Access Journals (Sweden)

    Daljit S. Karam

    2011-01-01

    Full Text Available Problem statement: A study was conducted to evaluate and compare the soil biological properties of a natural forest and an 18-year-old stand of Shorea leprosula in Chikus Forest Reserve, Perak, Malaysia. Approach: Soils were sampled at depths of 0-15 cm (topsoil and 15-30 cm (subsoil in six subplots (20×20 m of natural forest (C1 and of a planted S. leprosula (C2 plot. Fresh composite soil samples were kept in UV-sterilized polyethylene bags prior to analysis in the laboratory. The microbial population count was determined using a spread-plate count technique. The microbial enzymatic activity was elucidated using a Fluorescein Diacetate (FDA hydrolysis assay; microbial biomass was extracted using a rapid chloroform fumigation extraction method. The Microbial Biomass C (MBC was determined by wet dichromate oxidation; Kjeldahl digestion and a distillation method were used for evaluation of Microbial Biomass N (MBN. Results: Results indicate that only the microbial biomass N and the population count in the soil at the 0-15 cm depth were found to be higher in C1 compared to C2. The higher microbial population count in the soil at the 0-15 cm depth of C1 compared to C2 was enhanced by the large amount of organic matter that serves as a suitable medium for soil microbial growth. The higher MBN in the C1 soil was also influenced by the high content of organic material available that encourages activities of decomposing bacteria to take place. Similarities in the soil biological properties of the plots with regard to enzymatic activity and microbial biomass Care believed to be influenced by the same topographic gradient. The higher MBC/MBN ratios found in soils of C2 compared to C1 were due to the low availability of N compared to C, might result from N utilization by soil microbes for organic material decomposition. Conclusion: There are similarities in microbial enzymatic activity and biomass C, but not in microbial population counts and biomass N

  19. Assessment of penetration of Ascorbyl Tetraisopalmitate into biological membranes by molecular dynamics.

    Science.gov (United States)

    Machado, N C F; Dos Santos, L; Carvalho, B G; Singh, P; Téllez Soto, C A; Azoia, N G; Cavaco-Paulo, A; Martin, A A; Favero, P P

    2016-08-01

    The present work, involves the simulation of the transport of a vitamin C derivative, Ascorbyl Tetraisopalmitate (ATI), through human skin by molecular dynamics. Percutaneous absorption of the ATI molecule through the infundibulum, an important route of absorption into the hair follicle of the human skin, has been modeled and compared with the stratum corneum membrane. The comparative study was done using molecular dynamics with Martini force field. In infundibulum, a single ATI molecule require more time to penetrate, and the data obtained suggested that a high concentration of ATI molecule accelerated the process of penetration. In conclusion, the ATI molecule was found to have more affinity towards the stratum corneum as compared with the infundibulum, and it followed a straight pathway to penetrate (until 600ns of simulation). In the infundibulum, it showed less affinity, more mobility and followed a lateral pathway. Thus, this work contributes to a better understanding of the different molecular interactions during percutaneous absorption of active molecules in these two different types of biological membranes. PMID:27289538

  20. Application of Fourier transform infrared ellipsometry to assess the concentration of biological molecules.

    Science.gov (United States)

    Garcia-Caurel, Enric; Drévillon, Bernard; De Martino, Antonello; Schwartz, Laurent

    2002-12-01

    Spectroscopic ellipsometry is a noninvasive optical characterization technique mainly used in the semiconductor field to characterize bare substrates and thin films. In particular, it allows the gathering of information concerning the physical structure of the sample, such as roughness and film thickness, as well as its optical response. In the mid-infrared (IR) range each molecule exhibits a characteristic absorption fingerprint, which makes this technique chemically selective. Phase-modulated IR ellipsometry does not require a baseline correction procedure or suppression of atmospheric CO2 and water-vapor absorption bands, thus greatly reducing the subjectivity in data analysis. We have found that ellipsometric measurements of thin films, such as the solid residuals left on a plane surface after evaporation of a liquid drop containing a given compound in solution, are particularly favorable for dosing purposes because the intensity of IR absorptions shows a linear behavior along a wide range of solution concentrations of the given compound. Our aim is to illustrate with a concrete example and to justify theoretically the linearity experimentally found between radiation absorption and molecule concentration. For the example, we prepared aqueous solutions of glycogen, a molecule of huge biological importance currently tested in biochemical analyses, at concentrations ranging from 1 mg/l to 1 g/l which correspond to those found in physiological conditions. The results of this example are promising for the application of ellipsometry for dosing purposes in biochemistry and biomedicine. PMID:12477127

  1. Assessment of solid reactive mixtures for the development of biological permeable reactive barriers.

    Science.gov (United States)

    Pagnanelli, Francesca; Viggi, Carolina Cruz; Mainelli, Sara; Toro, Luigi

    2009-10-30

    Solid reactive mixtures were tested as filling material for the development of biological permeable reactive barriers for the treatment of heavy metals contaminated waters. Mixture selection was performed by taking into account the different mechanisms operating in sulphate and cadmium removal with particular attention to bioprecipitation and sorption onto the organic matrices in the mixtures. Suspensions of eight reactive mixtures were tested for sulphate removal (initial concentration 3 g L(-1)). Each mixture was made up of four main functional components: a mix of organic sources for bacterial growth, a neutralizing agent, a porous medium and zero-valent iron. The best mixture among the tested ones (M8: 6% leaves, 9% compost, 3% zero-valent iron, 30% silica sand, 30% perlite, 22% limestone) presented optimal conditions for SRB growth (pH 7.8 +/- 0.1; E(h)= -410 +/- 5 mV) and 83% sulphate removal in 22 days (25% due to bioreduction, 32% due to sorption onto compost and 20% onto leaves). M8 mixture allowed the complete abatement of cadmium with a significant contribution of sorption over bioprecipitation (6% Cd removal due to SRB activity). Sorption properties, characterised by potentiometric titrations and related modelling, were mainly due to carboxylic sites of organic components used in reactive mixtures.

  2. Fabrication, characterization, and biological assessment of multilayer laminin γ2 DNA coatings on titanium surfaces

    Science.gov (United States)

    Yang, Guoli; Zhang, Jing; Dong, Wenjing; Liu, Li; Shi, Jue; Wang, Huiming

    2016-03-01

    The purpose of this work was to fabricate a multilayer laminin γ2 DNA coating on a titanium surface and evaluate its biological properties. A multilayer laminin γ2 DNA coating was fabricated on titanium using a layer-by-layer assembly technique. The rate of coating degradation was evaluated by detecting the amount of cDNA remaining. Surface analysis using X-ray photoelectron spectroscopy, atomic force microscopy, and surface contact angle measurements revealed the multilayer structure to consist of cationic lipid and confirmed that a laminin γ2 DNA layer could be fabricated on titanium via the layer-by-layer assembly process. The transfection efficiency was highest for five layers in the multilayer structure. HEK293 cells cultured on the multilayer films displayed significantly higher adhesion activity than the control group. The expression of laminin γ2 and the co-localization of integrin β4 and plectin were more obvious in HN4 cells cultured on the multilayer laminin γ2 DNA coating, while weak immunoreactivities were observed in the control group. We concluded that the DNA-loaded multilayer provided a surface with good biocompatibility and that the multilayer laminin γ2 DNA coating might be effective in improving cell adhesion and the formation of hemidesmosomes on titanium surfaces.

  3. Assessment of biological changes in wheat seedlings induced by 12C6+-ion irradiation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Luwei; ZHANG Hong; ZHANG Xiaofu; ZHU Jianlan

    2008-01-01

    The present study was designed to evaluate the effect of 12C6+ ion beam (10~80 Gy) on biological changes of wheat seedlings. Reactive oxygen species (ROS)-related biomarkers and the quantification of plant survival and growth were examined at 10 day after carbon ions irradiation (LET: 30.8keV/μm). The results showed that heavy ions obviously enhanced ROSs reflected by the production of O2 and H2O2 as well as TBARS, and treatment with 20 Gy achieved the peak value, suggesting that higher mutagenic potential may occur at 20 Gy. Simultaneously, increase of SOD activity was induced by heavy ions to counteract ROS accumulation. On the other hand, higher doses at 40 and 80 Gy inhibited wheat growth and survival in comparison with the control, and reversely lower doses at 10 or 20 Gy stimulated wheat growth and survival. In conclusion, the above observations imply that a dose range of 20~40 Gy is likely promised for wheat mutation breeding.

  4. Osiris and SOMBRERO inertial confinement fusion power plant designs. Volume 2, Designs, assessments, and comparisons, Final report

    Energy Technology Data Exchange (ETDEWEB)

    Meier, W.R.; Bieri, R.L.; Monsler, M.J.

    1992-03-01

    The primary objective of the of the IFE Reactor Design Studies was to provide the Office of Fusion Energy with an evaluation of the potential of inertial fusion for electric power production. The term reactor studies is somewhat of a misnomer since these studies included the conceptual design and analysis of all aspects of the IFE power plants: the chambers, heat transport and power conversion systems, other balance of plant facilities, target systems (including the target production, injection, and tracking systems), and the two drivers. The scope of the IFE Reactor Design Studies was quite ambitious. The majority of our effort was spent on the conceptual design of two IFE electric power plants, one using an induction linac heavy ion beam (HIB) driver and the other using a Krypton Fluoride (KrF) laser driver. After the two point designs were developed, they were assessed in terms of their (1) environmental and safety aspects; (2) reliability, availability, and maintainability; (3) technical issues and technology development requirements; and (4) economics. Finally, we compared the design features and the results of the assessments for the two designs.

  5. Integrated plant safety assessment. Systematic evaluation program, Big Rock Point Plant (Docket No. 50-155). Final report

    International Nuclear Information System (INIS)

    The Systematic Evaluation Program was initiated in February 1977 by the U.S. Nuclear Regulatory Commission to review the designs of older operating nuclear reactor plants to reconfirm and document their safety. The review provides (1) an assessment of how these plants compare with current licensing safety requirements relating to selected issues, (2) a basis for deciding how these differences should be resolved in an integrated plant review, and (3) a documented evaluation of plant safety when the supplement to the Final Integrated Plant Safety Assessment Report has been issued. This report documents the review of the Big Rock Point Plant, which is one of ten plants reviewed under Phase II of this program. This report indicates how 137 topics selected for review under Phase I of the program were addressed. It also addresses a majority of the pending licensing actions for Big Rock Point, which include TMI Action Plan requirements and implementation criteria for resolved generic issues. Equipment and procedural changes have been identified as a result of the review

  6. Life Cycle Assessment of different uses of biogas from anaerobic digestion of separately collected biodegradable waste in France. Final report

    International Nuclear Information System (INIS)

    In the first part of the study, Gaz de France (GdF) and the French Environment Energy Management Agency (ADEME) wished to identify the best method to use the biogas from anaerobic digestion of separately collected biodegradable waste (bio-waste). Secondly, GdF and ADEME wished to evaluate the strength and weaknesses of the two main different organic recycling: anaerobic digestion (methanization) and composting. The study is based on the life cycle assessment method. The life cycle assessment used for this study consists in quantifying the environmental impacts of all of the activities which are related to the chosen use method. This methodology involves compiling a detailed account of all substances and energy flows removed or emitted from or into the environment at each stage of the life cycle. These flows are then translated into indicators of potential environment impacts. This methodology is based on the international standards ISO14040 and ISO 14044. The life cycle assessment was performed by RDC Environnement. In this study, two questions were treated: - Which is the best valorisation method for biogas produced from the anaerobic digestion of separately collected biodegradable waste: fuel, heat or electricity? ('Biogas' question); - Which is the best treatment for the separately collected biodegradable waste: anaerobic digestion (methanization) or industrial composting? ('Composting' question). The field of the study includes the arrival of the separately collected biodegradable waste at the anaerobic unit as well as the utilisation of the biogas energy and the agricultural use of the digestate from anaerobic digestion. For each biogas utilisation, the environmental impacts of each life cycle stage were considered as well as the impacts that were avoided due to the substitution of the use of non-renewable energy ('conventional' procedures). The modelling of the direct composting of the biodegradable waste was realised taking into account the followings

  7. Thermal stability of hepatitis E virus assessed by a molecular biological approach

    Directory of Open Access Journals (Sweden)

    Appel Bernd

    2011-10-01

    Full Text Available Abstract Background Hepatitis E virus (HEV is a pathogen of emerging concern in industrialized countries. The consumption of wild boar meat has been identified as one risk factor for autochthonous HEV infections. Only limited information is available about thermal stability of HEV, mainly due to the lack of rapid and efficient cell culture systems for measurement of HEV infectivity. Methods A molecular biological method was implemented in order to distinguish disassembled from intact viral particles using RNase treatment followed by quantitative real-time RT-PCR. The method was applied to a wild boar liver suspension containing HEV genotype 3. Results Time-course analyses indicated that the decline of protected RNA could be described by a biphasic model with an initial decrease followed by a stationary phase. The stationary phase was reached after 1 hour at 4°C, 3 days at 22°C and 7 days at 37°C with log reductions of 0.34, 0.45 and 1.24, respectively. Protected RNA was detectable until the end of the experiments at day 50 or 70. Heat exposure for 1 minute resulted in a log reduction of 0.48 at 70°C and increased with higher temperatures to 3.67 at 95°C. Although HEV infectivity titration by inoculation of the liver suspension onto three cell lines did not succeed, the results of the RNase-based method are in accordance with published cell culture-based data. Conclusions Measurement of intact viral particles using the RNase-based method may provide data on the stability of RNA viruses when cell culture-based infectivity titrations are not efficient or not available. The method enables processing of large sample numbers and may be suitable to estimate stability of HEV in different types of food.

  8. A microbiology-based multi-parametric approach towards assessing biological stability in drinking water distribution networks

    KAUST Repository

    Lautenschläger, Karin

    2013-06-01

    and sensitive tool to assess and evaluate biological stability and microbial processes in drinking water distribution systems. © 2013 Elsevier Ltd.

  9. Preliminary assessment of growth and survival of green alder (Alnus viridis), a potential biological stabilizer on fly ash disposal sites

    Institute of Scientific and Technical Information of China (English)

    Marcin Pietrzykowski; Wojciech Krzaklewski; Bartłomiej Wos´

    2015-01-01

    This paper presents preliminary assessment of seedling survival and growth of green alder (Alnus viridis (Chaix) DC. in Lam. & DC.) planted on fly ash disposal sites. This kind of post-industrial site is extremely hard to biologically stabilize without top-soiling. The experiment started with surface preparation using NPK start-up mineral fertilizer at 60–36–36 kg ha-1 followed by initial stabil-ization through hydro-seeding with biosolids (sewage sludge 4 Mg ha-1 dry mass) and a mixture of grasses (Dactylis glomerata L. and Lolium multiflorum Lam.) (200 kg ha-1). Subsequently, three-years-old green alder seedlings were planted in plots on two substrate variants:the control (directly on combustion waste) and plots with 3 dm3 lignite culm from a nearby mine introduced into the planting pit. Five years of preliminary monitoring show good survival seedling rates and growth parameters (height (h), average increase in height (△h), number of shoots (Lo) and leaf nitrogen supply in the fly ash disposal habitat. Treatment of the site with a combination of lignite culm in planting pits and preliminary surface preparation by hydro-seeding and mineral fertilization had the most positive effect on green alder seedling parameters. The results indicate that it is possible and beneficial to use green alder for biological stabilization on fly ash disposal sites.

  10. Minimal information: an urgent need to assess the functional reliability of recombinant proteins used in biological experiments

    Directory of Open Access Journals (Sweden)

    de Marco Ario

    2008-07-01

    Full Text Available Abstract Structural characterization of proteins used in biological experiments is largely neglected. In most publications, the information available is totally insufficient to judge the functionality of the proteins used and, therefore, the significance of identified protein-protein interactions (was the interaction specific or due to unspecific binding of misfolded protein regions? or reliability of kinetic and thermodynamic data (how much protein was in its native form?. As a consequence, the results of single experiments might not only become questionable, but the whole reliability of systems biology, built on these fundaments, would be weakened. The introduction of Minimal Information concerning purified proteins to add as metadata to the main body of a manuscript would render straightforward the assessment of their functional and structural qualities and, consequently, of results obtained using these proteins. Furthermore, accepted standards for protein annotation would simplify data comparison and exchange. This article has been envisaged as a proposal for aggregating scientists who share the opinion that the scientific community needs a platform for Minimum Information for Protein Functionality Evaluation (MIPFE.

  11. Proof of concept for a banding scheme to support risk assessments related to multi-product biologics manufacturing.

    Science.gov (United States)

    Card, Jeffrey W; Fikree, Hana; Haighton, Lois A; Blackwell, James; Felice, Brian; Wright, Teresa L

    2015-11-01

    A banding scheme theory has been proposed to assess the potency/toxicity of biologics and assist with decisions regarding the introduction of new biologic products into existing manufacturing facilities. The current work was conducted to provide a practical example of how this scheme could be applied. Information was identified for representatives from the following four proposed bands: Band A (lethal toxins); Band B (toxins and apoptosis signals); Band C (cytokines and growth factors); and Band D (antibodies, antibody fragments, scaffold molecules, and insulins). The potency/toxicity of the representative substances was confirmed as follows: Band A, low nanogram quantities exert lethal effects; Band B, repeated administration of microgram quantities is tolerated in humans; Band C, endogenous substances and recombinant versions administered to patients in low (interferons), intermediate (growth factors), and high (interleukins) microgram doses, often on a chronic basis; and Band D, endogenous substances present or produced in the body in milligram quantities per day (insulin, collagen) or protein therapeutics administered in milligram quantities per dose (mAbs). This work confirms that substances in Bands A, B, C, and D represent very high, high, medium, and low concern with regard to risk of cross-contamination in manufacturing facilities, thus supporting the proposed banding scheme.

  12. Biological Assessment of the Continued Operation of Los Alamos National Laboratory on Federally Listed Threatened and Endangered Species

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Leslie A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Ecology and Air Quality Group

    2006-09-19

    This biological assessment considers the effects of continuing to operate Los Alamos National Laboratory on Federally listed threatened or endangered species, based on current and future operations identified in the 2006 Site-wide Environmental Impact Statement for the Continued Operation of Los Alamos National Laboratory (SWEIS; DOE In Prep.). We reviewed 40 projects analyzed in the SWEIS as well as two aspects on ongoing operations to determine if these actions had the potential to affect Federally listed species. Eighteen projects that had not already received U.S. Fish and Wildlife Service (USFWS) consultation and concurrence, as well as the two aspects of ongoing operations, ecological risk from legacy contaminants and the Outfall Reduction Project, were determined to have the potential to affect threatened or endangered species. Cumulative impacts were also analyzed.

  13. Assessing twenty-first century skills through a teacher created video game for high school biology students

    Science.gov (United States)

    Annetta, Leonard A.; Cheng, Meng-Tzu; Holmes, Shawn

    2010-07-01

    As twenty-first century skills become a greater focus in K-12 education, an infusion of technology that meets the needs of today's students is paramount. This study looks at the design and creation of a Multiplayer Educational Gaming Application (MEGA) for high school biology students. The quasi-experimental, qualitative design assessed the twenty-first century skills of digital age literacy, inventive thinking, high productivity, and effective communication techniques of the students exposed to a MEGA. Three factors, as they pertained to these skills, emerged from classroom observations. Interaction with the teacher, discussion with peers, and engagement/time-on-task while playing the MEGA suggested that students playing an educational video game exhibited all of the projected twenty-first century skills while being engrossed in the embedded science content.

  14. Assessment of water quality at selected sites in the White River Basin, Indiana, 1993 and 1995 using biological indices

    Science.gov (United States)

    Frey, Jeffrey W.; Baker, N.T.; Lydy, M.J.; Stone, W.W.

    1996-01-01

    As part of the National Water Quality Assessment (NAWQA) Program, fish communities were sampled at 11 sites in the White River Basin, Indiana, in 1993 and 1995 to help determine water-quality conditions. Ninety-one species of fish with representatives from 18 families were collected in the basin. Total numbers of fish collected at every site increased between collection years. The Index of Biological Integrity (IBI) and Qualitative Habitat Evaluation Index (QHEI) were calculated for all 11 sites in 1995. The QHEI scores indicated six sites had excellent habitat to support fish communities. Only three sites were rated in the “good” to “excellent” IBI water-quality categories, indicating some type of nonhabitat environmental degradation to the fish communities. Eight of the sites were rated in the “fair,” “poor,” or “very poor” IBI water-quality categories.

  15. Biological affinities and adaptations of Bronze Age Bactrians: III. An initial craniometric assessment.

    Science.gov (United States)

    Hemphill, B E

    1998-07-01

    Discovery of a previously unknown Bronze Age civilization (Oxus Civilization) centered on the oases of Central Asia immediately raised questions concerning the origin and interregional impacts of this civilization. Fifteen craniometric variables from 12 Bronze Age samples--encompassing 544 adults from Central Asia, Iran, the Indus Valley, and Anatolia--are compared to test which, if any, of the current hypotheses offered by archaeologists are best supported by the pattern of phenetic affinities possessed by the Oxus Civilization inhabitants of the north Bactrian oasis. Craniometric differences between samples are compared with Mahalanobis generalized distance, and patterns of phenetic affinity are assessed with two types of cluster analysis (WPGMA, neighbor-joining method), multidimensional scaling, and principal coordinates analysis. Results obtained by this analysis indicate that current hypotheses for both the origin and interregional impacts of Oxus Civilization populations are incomplete. PMID:9696149

  16. Biologically active secondary metabolites of barley. I. Developing techniques and assessing allelopathy in barley.

    Science.gov (United States)

    Liu, D L; Lovett, J V

    1993-10-01

    Allelopathic effects of barley (Hordeum vulgare L.) on white mustard (Sinapis alba L.) were assessed using modified bioassays that reduced other environmental influences. In a Petri dish bioassay, germination of white mustard was delayed and the radicle lengths were significantly inhibited at a density of 0.5 barley seed/cm(2). In a 'siphoning' bioassay apparatus, when the two species were sown together, radicle elongation of white mustard was not inhibited one day after sowing but became increasingly inhibited as bioassay time increased. Barley allelochemicals were released from the roots in a hydroponic system for at least 70 days after commencement of barley germination. Solutions removed from the hydroponic system of growing barley delayed germination and inhibited growth of white mustard. The allelopathic activity of barley was further confirmed at a density of 0.3 barley seed/cm(2) in a modified stairstep apparatus. PMID:24248571

  17. Role of serum eosinophil cationic protein as a biological marker to assess the severity of bronchial asthma

    International Nuclear Information System (INIS)

    Objective: The study was carried out to evaluate the role of serum eosinophil cationic protein (ECP) as a biological marker for the diagnosis and to assess the severity of bronchial asthma. Methodology: This observational cross-sectional study was conducted among 70 bronchial asthma patients and 45 disease controls (tuberculosis-15, chronic obstructive pulmonary disease-15, interstitial lung disease-15) enrolled from patients attending the outpatient department of the National Institute of Disease of the Chest and Hospital (NIDCH), Dhaka, Bangladesh during July 2010 to June 2011. Global Initiative of Asthma Management and Prevention (GINA) criteria were followed for selection of both atopic and non-atopic patients with intermittent or persistent (mild, moderate and severe) asthma. Serum level of eosinophil cationic protein (ECP), IgE, forced expiratory volume in 1 second (FEV 1% predicted) and circulatory eosinophil (CE) count were estimated. Results: Mean serum ECP level (28.8 +- 42.9 vs. 6.82 +- 3.5 ng/mL; P<0.001), IgE level (383.59 - 225.3 vs. 135 +- 131.8 IU/mL; P<0.001) and percent circulatory eosinophil count (9.95 +- 3.7 vs. 5.95 +- 1.4; P<0.024) were all found significantly raised among asthma patients than disease controls but % FEV1 was equivocal. All grades of persistent asthma patients had significantly (P<0.025 and P<0.002) higher mean ECP level than intermittent cases but serum IgE level and CE count did not differ significantly. FEV1 % predicted correlated well among moderate and severe persistent asthma but was equivocal for intermittent and mild persistent cases. Conclusion: This study has reinforced that serum eosinophil cationic protein is a dependable biological marker with more discriminatory power over other indicators for bronchial asthma and to assess its severity. (author)

  18. Quantitative assessments of morphological and functional properties of biological trees based on their fractal nature.

    Science.gov (United States)

    Kamiya, Akira; Takahashi, Tatsuhisa

    2007-06-01

    The branching systems in our body (vascular and bronchial trees) and those in the environment (plant trees and river systems) are characterized by a fractal nature: the self-similarity in the bifurcation pattern. They increase their branch density toward terminals according to a power function with the exponent called fractal dimension (D). From a stochastic model based-on this feature, we formulated the fractal-based integrals to calculate such morphological parameters as aggregated branch length, surface area, and content volume for any given range of radius (r). It was followed by the derivation of branch number and cross-sectional area, by virtue of the logarithmic sectioning of the r axis and of the branch radius-length relation also given by a power function of r with an exponent (alpha). These derivatives allowed us to quantify various hydrodynamic parameters of vascular and bronchial trees as fluid conduit systems, including the individual branch flow rate, mean flow velocity, wall shear rate and stress, internal pressure, and circumferential tension. The validity of these expressions was verified by comparing the outcomes with actual data measured in vivo in the vascular beds. From additional analyses of the terminal branch number, we found a simple equation relating the exponent (m) of the empirical power law (Murray's so-called cube law) to the other exponents as (m=D+alpha). Finally, allometric studies of mammalian vascular trees revealed uniform and scale-independent distributions of terminal arterioles in organs, which afforded an infarct index, reflecting the severity of tissue damage following arterial infarction. PMID:17347385

  19. Assessment and evaluation of speciation tools for the study of uranium (6) circulating biological species

    International Nuclear Information System (INIS)

    The aim of this work is the development of tools allowing the study of uranium VI speciation in inorganic and organic environments, and in particular in the blood environment. The characterization of the different complexed forms of the uranyl ion has been improved by combining two techniques: the time resolution laser spectro-fluorimetry (TRLS) and the capillary electrophoresis (CE). CE is a developing separative analytical technique with a strong resolution. Therefore, the following studies have been carried out: the analysis of the speciation of hydroxo complexes of the uranyl ion by indirect UV detection, with the qualitative identification of the (UO2)2(OH)22+ and (UO2)3(OH)5+ complexes; the application of the iso-electrical focussing mode in order to show the uranium-transferrin complexing; the evaluation of the electrophoretic mobility of UO22+ and the interactions with the phosphate, hydroxo-isobutyric acid (HIBA) and citrate ligands; and the study of the U(VI)-blood serum system with the separation of the different seric proteins and the influence of U(VI) on electrophoretic profiles. two points are important to consider in the development of the system: the coupling with an on-line detector (mass spectrometer, counter, laser) and the surface grafting of the capillaries used. The TRLS is a system used in geology, in the Purex process chemistry, in medical and environmental control, and in nuclear wastes management. After having analyzed the influence of different ligands (citrate, phosphate, carbonate, transferrin) in the fluorescence spectra of uranium (VI), the complexing conditional constant (K) of the U(VI)-transferrin system has been evaluated for the first time using a mathematical model and the titration. A study performed on blood plasma has permitted to show a U(VI)-phosphates complexing and finally, three phosphate complexes UO2H2PO4+, UO2HPO4 and UO2PO4+ have been characterized both spectrally and temporarily. (J.S.)

  20. Assessment of the removal of estrogenicity in biological nutrient removal wastewater treatment processes

    International Nuclear Information System (INIS)

    The removal of estrogenicity in a University of Cape Town-biological nutrient removal (UCT-BNR) wastewater treatment process was investigated using pilot and bench scale systems, batch experiments and mathematical modeling. In the pilot BNR process, 96 ± 5% of the estrogenicity exerted by the influent wastewater was removed by the treatment process. The degradation efficiencies in the anaerobic, anoxic and aerobic zones of the pilot BNR bioreactor were 11 ± 9%, 18 ± 2% and 93 ± 10%, respectively. In order to further understand the performance of the BNR process in the removal of estrogenicity from wastewater, a bench scale BNR process was operated with synthetic wastewater dosed with E1 and E2. The removal of estrogenicity in the bench scale system (95 ± 5%) was comparable to the pilot BNR process and the degradation efficiencies were estimated to be 8 ± 0.8%, 38 ± 4% and 85 ± 22% in the anaerobic, anoxic and aerobic zones, respectively. A biotransformation model developed to predict the fate of E1 and E2 in batch tests using the sludge from the BNR process was calibrated using the data from the experiments. The biotransformation rate constants for the transformation of E2 to E1 were estimated as 71 ± 1.5, 31 ± 3.3 and 1 ± 0.9 L g COD−1 d−1 for the aerobic, anoxic and anaerobic batch tests, respectively, while the corresponding biotransformation rate constants for the transformation of E1 were estimated to be 7.3 ± 1.0, 3 ± 2.0, and 0.85 ± 0.6 L·g COD−1 d−1. A steady state mass balance model formulated to describe the interactions between E2 and E1 in BNR activated sludge reasonably described the fate of E1 and E2 in the BNR process. - Highlights: • Comparable estrogenicity removal was observed from two BNR processes. • Pseudo first order model described the transformation of E2 and E1 in BNR process. • Biotransformation of E1 in BNR activated sludge controls the degradation of E2