Electrical Bioimpedance-Controlled Surgical Instrumentation.

Science.gov (United States)

Brendle, Christian; Rein, Benjamin; Niesche, Annegret; Korff, Alexander; Radermacher, Klaus; Misgeld, Berno; Leonhardt, Steffen

2015-10-01

A bioimpedance-controlled concept for bone cement milling during revision total hip replacement is presented. Normally, the surgeon manually removes bone cement using a hammer and chisel. However, this procedure is relatively rough and unintended harm may occur to tissue at any time. The proposed bioimpedance-controlled surgical instrumentation improves this process because, for example, most risks associated with bone cement removal are avoided. The electrical bioimpedance measurements enable online process-control by using the milling head as both a cutting tool and measurement electrode at the same time. Furthermore, a novel integrated surgical milling tool is introduced, which allows acquisition of electrical bioimpedance data for online control; these data are used as a process variable. Process identification is based on finite element method simulation and on experimental studies with a rapid control prototyping system. The control loop design includes the identified process model, the characterization of noise as being normally distributed and the filtering, which is necessary for sufficient accuracy ( ±0.5 mm). Also, in a comparative study, noise suppression is investigated in silico with a moving average filter and a Kalman filter. Finally, performance analysis shows that the bioimpedance-controlled surgical instrumentation may also performs effectively at a higher feed rate (e.g., 5 mm/s).

The role of bioimpedance and biomarkers in helping to aid clinical decision-making of volume assessments in dialysis patients.

Science.gov (United States)

Davies, Simon J; Davenport, Andrew

2014-09-01

Bioimpedance analysis (BIA) derives two main pieces of information--total tissue fluid content, which when referring to the whole patient is equivalent to the total body water (TBW), and cell mass, which in the limbs mainly reflects muscle. The relationship between these measures, expressed in different ways, is abnormal in dialysis patients due to muscle wasting combined with tissue overhydration. In both dialysis modalities this is associated with aging, comorbidity, and inflammation, and there is a conflict between achieving euvolemia to improve blood pressure control and prevent left ventricular hypertrophy on one hand, but risking episodes of hypovolemia and loss of residual renal function on the other. In peritoneal dialysis, the situation is exacerbated by hypoalbuminemia, whereas in hemodialysis BIA is unable to distinguish between the plasma volume and tissue edema components of interdialytic weight gain. In longitudinal studies BIA can identify changes in hydration following a defined intervention, and spontaneous loss in TBW consequent on muscle wasting not appreciated clinically, resulting in a failure to sufficiently reduce the dry weight. Cardiac biomarkers provide additional information but it is not clear whether this reflects fluid status or underlying structural organ damage. Intervention studies are now needed that show how this information is best used to improve patient outcomes, including meaningful end points such as hospitalization and survival.

Bioelectrical impedance analysis (BIA) equations validation against hydrodensitometry in a Colombian population

International Nuclear Information System (INIS)

Caicedo-Eraso, J C; Gonzalez-Correa, C A; Gonzalez-Correa, C H

2013-01-01

Several studies have shown that the accuracy of BIA results depends of ethnicity, age, gender, hormonal and genetic variations and, so far, there are not specific equations for Colombian population. The purpose was to evaluate reported BIA equations to determine their usefulness in body composition assessment in young females from Colombia using hydrodensitometry as the reference method. A sample of 30 young females was evaluated. Inclusion and exclusion criteria were defined to minimize the variability of BIA. Height, weight, multi-frequency BIA, residual lung volume (RV) and underwater weight (UWW) were measured. Five BIA equations met the inclusion criteria of this study. Three equations overestimated and two equations underestimated body fat (BF). Paired Student t-test and Bland and Altman analysis (p<0.05) showed significant differences in four BIA equations. However, all standard error of estimate (SEE) to BF was greater than 2.7 kg. This study showed that the five selected BIA equations are not valid for estimation of body composition in young females from Colombia. It is recommended to develop BIA equations to improve BF fat assessment in our population.

[Abdomen specific bioelectrical impedance analysis (BIA) methods for evaluation of abdominal fat distribution].

Science.gov (United States)

Ida, Midori; Hirata, Masakazu; Hosoda, Kiminori; Nakao, Kazuwa

2013-02-01

Two novel bioelectrical impedance analysis (BIA) methods have been developed recently for evaluation of intra-abdominal fat accumulation. Both methods use electrodes that are placed on abdominal wall and allow evaluation of intra-abdominal fat area (IAFA) easily without radiation exposure. Of these, "abdominal BIA" method measures impedance distribution along abdominal anterior-posterior axis, and IAFA by BIA method(BIA-IAFA) is calculated from waist circumference and the voltage occurring at the flank. Dual BIA method measures impedance of trunk and body surface at the abdominal level and calculates BIA-IAFA from transverse and antero-posterior diameters of the abdomen and the impedance of trunk and abdominal surface. BIA-IAFA by these two BIA methods correlated well with IAFA measured by abdominal CT (CT-IAFA) with correlatipn coefficient of 0.88 (n = 91, p abdominal adiposity in clinical study and routine clinical practice of metabolic syndrome and obesity.

Multifrequency right-side, localized and segmental BIA obtained with different bioimpedance analysers

International Nuclear Information System (INIS)

Bogónez-Franco, P; McAdams, E; Nescolarde, L; Rosell-Ferrer, J

2015-01-01

The aim of this study is to compare two commercial bioimpedance analysers, BioparHom Z-Métrix and Impedimed SFB7, measuring the impedance of three different body segments. The segments measured were ‘right-side’ (or ‘whole-body’), ‘segmental right-lower limb’ and ‘localized longitudinal right-quadriceps’. The comparison was made on electrical models of each segment, including electrode–skin impedance, and in vivo on nine healthy volunteers. Both devices are designed to measure right-side impedances and, in the present study, as the length of the segment investigated decreased, the accuracy of the impedance measured was found to decrease. The accuracy of the devices was calculated via measurements performed on RC networks of known values. It was found that adding electrode–skin contact impedances in the electrical model affected the accuracy by both devices. (paper)

Changes in Intracellular Water Following Hemodialysis Treatment Lead to Changes in Estimates of Lean Tissue Using Bioimpedance Spectroscopy.

Science.gov (United States)

El-Kateb, Sally; Davenport, Andrew

2016-06-01

Bioelectrical impedance (BIA) devices are being introduced into hemodialysis (HD) centers to aid determining normohydrated weight and also provide body composition assessment by estimating lean tissue mass index (LTMI) and fat mass index (FMI). BIA devices differ, with most using a 2-body compartmental model, which can be affected by hydration status, and as such for reliable measurements, these should be made postdialysis when patients are not overhydrated, which is inconvenient for both patients and staff. The development of BIA devices using a 3-compartmental body model, separately estimating normohydrated LTMI potentially, now offers the advantage of making reliable measurements of body composition prior to dialysis. We measured body composition predialysis and postdialysis in 50 HD patients using a 3-body compartment model BIA device. Although there were no statistically significant differences for the whole cohort in LTMI and FMI (pre and post HD-13.5 ± 4.2 vs 13.9 ± 4.7 kg/m(2), and 10.5 ± 5.5 vs 10.6 ± 5.4 kg/m(2) respectively), the correlation (r(2)) between pre and post HD was only 0.27 and 0.37 kg/m(2) respectively, with a mean ± SD bias on Bland-Altman analysis, -0.67 ± 4.25 and 0.33 ± 4.77 kg/m(2) respectively. Changes in intracellular water were associated with changes in LTMI (r(2) = 0.99, P < .001). Similarly, a fall in LTMI was associated with a corresponding increase in FMI (r(2) = -0.86, P < .001). In clinical practice, predialysis bioimpedance measurements are more convenient. However, for more reliable and reproducible assessments of nutrition status, we suggest that measurements of body composition should be made when patients are not overhydrated. © 2015 American Society for Parenteral and Enteral Nutrition.

Effects of muscle injury severity on localized bioimpedance measurements

International Nuclear Information System (INIS)

Nescolarde, L; Rosell-Ferrer, J; Yanguas, J; Lukaski, H; Alomar, X; Rodas, G

2015-01-01

Muscle injuries in the lower limb are common among professional football players. Classification is made according to severity and is diagnosed with radiological assessment as: grade I (minor strain or minor injury), grade II (partial rupture, moderate injury) and grade III (complete rupture, severe injury). Tetrapolar localized bioimpedance analysis (BIA) at 50 kHz made with a phase-sensitive analyzer was used to assess damage to the integrity of muscle structures and the fluid accumulation 24 h after injury in 21 injuries in the quadriceps, hamstring and calf, and was diagnosed with magnetic resonance imaging (MRI). The aim of this study was to identify the pattern of change in BIA variables as indicators of fluid [resistance (R)] and cell structure integrity [reactance (Xc) and phase angle (PA)] according to the severity of the MRI-defined injury. The % difference compared to the non-injured contralateral muscle also measured 24-h after injury of R, Xc and PA were respectively: grade I (n = 11; −10.4, −17.5 and −9.0%), grade II (n = 8; −18.4, −32.9 and −16.6%) and grade III (n = 2; −14.1, −52.9 and −43.1%), showing a greater significant decrease in Xc (p < 0.001). The greatest relative changes were in grade III injuries. However, decreases in R, that indicate fluid distribution, were not proportional to the severity of the injury. Disruption of the muscle structure, demonstrated by the localized determination of Xc, increased with the severity of muscle injury. The most significant changes 24 h after injury was the sizeable decrease in Xc that indicates a pattern of disrupted soft tissue structure, proportional to the severity of the injury. (paper)

BIOIMPEDANCE ANALYSIS IN HAEMODIALYSIS PRACTICE: SHORT REVIEW AND SINGLE CENTER EXPERIENCE

Directory of Open Access Journals (Sweden)

A.G. Strokov

2012-01-01

Full Text Available Bioimpedance analysis has been widely used to estimate a hydration state, lean and fat mass in haemodialysis patients. The aim of our study was to investigate the validity and usefulness of bioimpedance analysis in routine dialysis practice. Last two years we used the body composition monitoring (BCM, Fresenius Medical Care, method based on whole body multifrequency bioimpedance spectroscopy (BIS, compared with traditional clinical data. For BIS data verification, hydration status of 32 stable HD patients with dialysis vintage more than 3 years and clinically well established dry weight were studied. Only in three cases BIS data seems underestimated in serial measurements. Next step, 28 healthy subjects and 116 dialysis patients were studied. Total body water and extracellular volume (ECV were significantly higher in dialysis group (P<0.01, and there was not any difference in intracellular volume (ICV. Mean AP was similar in patients with moderate (<15% and massive (>15% relative overhydration (RO = overhydration / ECV, at the same time, average number of antihypertensive medications was significantly higher in more overhydrated patients (3.1 vs 1.2. In clinical practice RO is more convenient indicator as compared to standard overhydration volume /dry weight ratio. Mutual application of the BIS and blood volume monitoring allows more rapid and safe dry weight achievement. BIS was useful tool for hydration status monitoring in routine haemodialysis practice, and further work need to be done to clarify BIS validity for nutritional status estimation. 

Comparison of hydration and nutritional status between young and elderly hemodialysis patients through bioimpedance analysis

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Lee JE

2015-08-01

Full Text Available Jung Eun Lee,1,2 In Young Jo,3 Song Mi Lee,3 Woo Jeong Kim,3 Hoon Young Choi,2,4 Sung Kyu Ha,4 Hyung Jong Kim,5 Hyeong Cheon Park2,4 1Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, 2Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, 3Department of Nutrition Services, Gangnam Severance Hospital, 4Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, 5Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea Background: The number of elderly people on dialysis is increasing rapidly. Fluid overload and malnutrition status are serious problems in elderly dialysis patients. We aimed to compare the hydration and nutritional status through bioimpedance analysis (BIA between young and elderly hemodialysis (HD patients and to analyze risk factors related to fluid overload and malnutrition status in these patients.Method: We conducted a cross-sectional study, in which 82 HD (males 42, mean age 58.7±12.9 years patients were enrolled. We collected different types of data: laboratory data, such as serum creatinine, albumin, total iron-binding capacity, hemoglobin, total cholesterol; anthropometric data, such as hand grip strength (HGS; BIA data, such as intracellular water, skeletal muscle mass, body cell mass, bone mineral content, phase angle (PhA, extra cellular water (ECW/total body water (TBW ratio; and malnutrition-inflammation score (MIS, which is a traditional nutritional parameter for dialysis patients. All patients were stratified into two groups according to their age: young (<65 years [n=54] and elderly (≥65 years [n=28].Results: Total iron-binding capacity and HGS were significantly lower in elderly HD patients than in young HD patients (198.9±35.6 vs 221.4±52.1 mcg/dL; and 22.4±10.3 vs 36.4±23.2 kg, respectively (P<0.05. Also, intracellular water and Ph

II Latin American Conference on Bioimpedance

CERN Document Server

Bertemes-Filho, Pedro

2016-01-01

This volume presents the proceedings of CLABIO 2015 - II Latin American Conference on Bioimpedance, held in Montevideo, Uruguay - September 30 - October 02, 2015. The works cover a broad range in Biomedical Engineering and Computing, Medical Physics and Medical Sciences, Environment, Biology and Chemistry. The topics are: ·Bioimpedance Applications ·Bioimpedance Instrumentation ·Body and Tissue Composition ·Cell Culture and Cell Suspension ·Electrical Impedance Tomography ·Electrode Modelling ·Magnetic Induction - Electrical Impedance Tomography ·Magnetic Resonance - Electrical Impedance Tomography ·Nonlinear Phenomena ·Organ and Tissue Impedance ·Plant Tissue Impedance ·Skin Impedance Modelling ·Technological Advances in Bioimpedance ·Theory and Modelling.

An efficient analysis of nanomaterial cytotoxicity based on bioimpedance

International Nuclear Information System (INIS)

Kandasamy, Karthikeyan; Kim, Sanghyo; Choi, Cheol Soo

2010-01-01

In the emerging nanotechnology field, there is an urgent need for the development of a significant and sensitive method that can be used to analyse and compare the cytotoxicities of nanomaterials such as carbon nanotubes (CNTs) and gold nanoparticles (AuNPs), since such materials can be applied as contrast agents or drug delivery carriers. The bioimpedance system possesses great potential in many medical research fields including nanotechnology. Electric cell-substrate impedance sensing (ECIS) is a particular bioimpedance system that offers a real-time, non-invasive, and quantitative measurement method for the cytotoxicity of various materials. The present work compared the cytotoxicity of AuNPs to that of purchased single-walled carbon nanotubes (SWCNTs). The size-controlled and monodispersed AuNPs were synthesized under autoclaved conditions and reduced by ascorbic acid (AA) whereas the purchased SWCNTs were used without any surface modifications. Bioimpedance results were validated by conventional WST-1 and trypan blue assays, and transmission electron microscopy (TEM) and field emission scanning electron microscopy (FE-SEM) were performed to examine nanomaterials inside the VERO cells. This research evaluates the ability of the ECIS system compared to those of conventional methods in analyzing the cytotoxicity of AuNPs and SWCNTs with higher sensitivity under real-time conditions.

Use of electrocardiogram (ECG) electrodes for Bioelectrical Impedance Analysis (BIA)

International Nuclear Information System (INIS)

Caicedo-Eraso, J C; González-Correa, C H; González-Correa, C A

2012-01-01

BIA is a safe, noninvasive, portable and relatively inexpensive method of estimating body composition that is practical and suitable for individual use and large-scale studies. However, the cost of the electrodes recommended by some BIA manufacturers is too high for developing countries; where very often the long and complicated process of importation reduces the time they can be used. The purpose of this study was to evaluate the use of two types of ECG electrodes (2290 and 2228 by 3M ® ) in BIA measurements to decrease the costs of the test. The results showed that the 2228 ECG electrodes can be used in BIA measurements for adult's body composition assessment. These electrodes are available in the domestic market and their costs are 92% lower than the electrodes recommended by manufacturer. The results show a new cost-benefit relation for BIA method and make this a more accessible tool for individual tests, large-scale researches and studies in the community.

Detection of muscle gap by L-BIA in muscle injuries: clinical prognosis.

Science.gov (United States)

Nescolarde, L; Yanguas, J; Terricabras, J; Lukaski, H; Alomar, X; Rosell-Ferrer, J; Rodas, G

2017-06-21

Sport-related muscle injury classifications are based basically on imaging criteria such as ultrasound (US) and magnetic resonance imaging (MRI) without consensus because of a lack of clinical prognostics for return-to-play (RTP), which is conditioned upon the severity of the injury, and this in turn with the muscle gap (muscular fibers retraction). Recently, Futbol Club Barcelona's medical department proposed a new muscle injury classification in which muscle gap plays an important role, with the drawback that it is not always possible to identify by MRI. Localized bioimpedance measurement (L-BIA) has emerged as a non-invasive technique for supporting US and MRI to quantify the disrupted soft tissue structure in injured muscles. To correlate the severity of the injury according to the gap with the RTP, through the percent of change in resistance (R), reactance (Xc) and phase-angle (PA) by L-BIA measurements in 22 muscle injuries. After grouping the data according to the muscle gap (by MRI exam), there were significant differences in R between grade 1 and grade 2f (myotendinous or myofascial muscle injury with feather-like appearance), as well as between grade 2f and grade 2g (myotendinous or myofascial muscle injury with feather and gap). The Xc and PA values decrease significantly between each grade (i.e. 1 versus 2f, 1 versus 2g and 2f versus 2g). In addition, the severity of the muscle gap adversely affected the RTP with significant differences observed between 1 and 2g as well as between 2f and 2g. These results show that L-BIA could aid MRI and US in identifying the severity of an injured muscle according to muscle gap and therefore to accurately predict the RTP.

Bioimpedance and Fluid Status in Children and Adolescents Treated With Dialysis.

Science.gov (United States)

Milani, Gregorio P; Groothoff, Jaap W; Vianello, Federica A; Fossali, Emilio F; Paglialonga, Fabio; Edefonti, Alberto; Agostoni, Carlo; Consonni, Dario; van Harskamp, Dewi; van Goudoever, Johannes B; Schierbeek, Henk; Oosterveld, Michiel J S

2017-03-01

Assessment of hydration status in patients with chronic kidney failure treated by dialysis is crucial for clinical management decisions. Dilution techniques are considered the gold standard for measurement of body fluid volumes, but they are unfit for day-to-day care. Multifrequency bioimpedance has been shown to be of help in clinical practice in adults and its use in children and adolescents has been advocated. We investigated whether application of multifrequency bioimpedance is appropriate for total-body water (TBW) and extracellular water (ECW) measurement in children and adolescents on dialysis therapy. A study of diagnostic test accuracy. 16 young dialysis patients (before a hemodialysis session or after peritoneal dialysis treatment) from the Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, and the Emma Children's Hospital-Academic Medical Center, Amsterdam, the Netherlands. TBW and ECW volumes assessed by multifrequency bioimpedance. TBW and ECW volumes measured by deuterium and bromide dilution, respectively. Mean TBW volumes determined by multifrequency bioimpedance and deuterium dilution were 19.2±8.7 (SD) and 19.3±8.3L, respectively; Bland-Altman analysis showed a mean bias between the 2 methods of -0.09 (95% limits of agreement, -2.1 to 1.9) L. Mean ECW volumes were 8.9±4.0 and 8.3±3.3L measured by multifrequency bioimpedance and bromide dilution, respectively; mean bias between the 2 ECW measurements was +0.6 (95% limits of agreement, -2.3 to 3.5). Participants ingested the deuterated water at home without direct supervision by investigators, small number of patients, repeated measurements in individual patients were not performed. Multifrequency bioimpedance measurements were unbiased but imprecise in comparison to dilution techniques. We conclude that multifrequency bioimpedance measurements cannot precisely estimate TBW and ECW in children receiving dialysis. Copyright © 2016 National Kidney Foundation, Inc. Published by Elsevier

Combining Near-Subject Absolute and Relative Measures of Longitudinal Hydration in Hemodialysis

OpenAIRE

Chan, Cian; McIntyre, Christopher; Smith, David; Spanel, Patrik; Davies, Simon J.

2009-01-01

Background and objectives: The feasibility and additional value of combining bioimpedance analysis (BIA) with near-subject absolute measurement of total body water using deuterium dilution (TBWD) in determining longitudinal fluid status was investigated.

Gastric Tissue Damage Analysis Generated by Ischemia: Bioimpedance, Confocal Endomicroscopy, and Light Microscopy

Directory of Open Access Journals (Sweden)

Nohra E. Beltran

2013-01-01

Full Text Available The gastric mucosa ischemic tissular damage plays an important role in critical care patients’ outcome, because it is the first damaged tissue by compensatory mechanism during shock. The aim of the study is to relate bioimpedance changes with tissular damage level generated by ischemia by means of confocal endomicroscopy and light microscopy. Bioimpedance of the gastric mucosa and confocal images were obtained from Wistar male rats during basal and ischemia conditions. They were anesthetized, and stain was applied (fluorescein and/or acriflavine. The impedance spectroscopy catheter was inserted and then confocal endomicroscopy probe. After basal measurements and biopsy, hepatic and gastric arteries clamping induced ischemia. Finally, pyloric antrum tissue was preserved in buffered formaldehyde (10% for histology processing using light microscopy. Confocal images were equalized, binarized, and boundary defined, and infiltrations were quantified. Impedance and infiltrations increased with ischemia showing significant changes between basal and ischemia conditions (. Light microscopy analysis allows detection of general alterations in cellular and tissular integrity, confirming gastric reactance and confocal images quantification increments obtained during ischemia.

THE RESULTS OF THE ANALYSIS OF THE STUDENTS’ BODY COMPOSITION BY BIOIMPEDANCE METHOD

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Dmitry S. Blinov

2016-06-01

Full Text Available Introduction. Tissues of the human body can conduct electricity. Liquid medium (water, blood, the contents of hollow bodies, have a low impedance, i.e. good conductors, while denser tissue (muscle, nerves, etc. resistance is significantly higher. The biggest impedance have fat and bone tissues. The bioimpendancemetry – a method which allows to determine the composition of the human body by measuring electrical resistance (impedance of its tissues. Relevance. This technique is indispensable to dieticians and fitness trainers. In addition, the results of the study can provide invaluable assistance in the appointment of effective treatment physicians, gynecologists, orthopedists, and other specialists. The bioimpedance method helps to determine the risks of developing diabetes type 2, atherosclerosis, hypertension, diseases of the musculoskeletal system, disorders of the endocrine system, gall-stone disease and etc. Materials and Methods. In the list of parameters of body composition assessed by bioimpedance analysis method, included absolute and relative indicators. Depending on the method of measurement of the absolute rates were determined for the whole body. To absolute performance were: fat and skinny body mass index, active cell and skeletal muscle mass, total body water, cellular and extracellular fluid. Along with them were calculated relatively (normalized to body weight, lean mass, or other variables indicators of body composition. Results. In the result of the comparison of anthropometric and bioimpedance method found that growth performance, vital capacity, weight, waist circumference, circumfer¬ence of waist and hip, basal metabolism, body fat mass, normalized on growth, lean mass, percentage skeletal muscle mass in boys and girls with normal and excessive body weight had statistically significant differences. Discussion and Conclusions. In the present study physical development with consideration of body composition in students

Multi-frequency bioimpedance in equine muscle assessment

International Nuclear Information System (INIS)

Harrison, Adrian Paul; Elbrønd, Vibeke Sødring; Riis-Olesen, Kiwa; Bartels, Else Marie

2015-01-01

Multi-frequency BIA (mfBIA) equipment has been shown to be a non-invasive and reliable method to assess a muscle as a whole or at fibre level. In the equine world this may be the future method of assessment of training condition or of muscle injury. The aim of this study was to test if mfBIA reliably can be used to assess the condition of a horse’s muscles in connection with health assessment, injury and both training and re-training. mfBIA measurements was carried out on 10 ‘hobby’ horses and 5 selected cases with known anamnesis. Impedance, resistance, reactance, phase angle, centre frequency, membrane capacitance and both extracellular and intracellular resistance were measured. Platinum electrodes in connection with a conductance paste were used to accommodate the typical BIA frequencies and to facilitate accurate measurements. Use of mfBIA data to look into the effects of myofascial release treatment was also demonstrated. Our findings indicate that mfBIA provides a non-invasive, easily measurable and very precise assessment of the state of muscles in horses. This study also shows the potential of mfBIA as a diagnostic tool as well as a tool to monitor effects of treatment e.g. myofascial release therapy and metabolic diseases, respectively. (paper)

Bioimpedance Harmonic Analysis as a Diagnostic Tool to Assess Regional Circulation and Neural Activity

International Nuclear Information System (INIS)

Mudraya, I S; Revenko, S V; Khodyreva, L A; Markosyan, T G; Dudareva, A A; Ibragimov, A R; Romich, V V; Kirpatovsky, V I

2013-01-01

The novel technique based on harmonic analysis of bioimpedance microvariations with original hard- and software complex incorporating a high-resolution impedance converter was used to assess the neural activity and circulation in human urinary bladder and penis in patients with pelvic pain, erectile dysfunction, and overactive bladder. The therapeutic effects of shock wave therapy and Botulinum toxin detrusor injections were evaluated quantitatively according to the spectral peaks at low 0.1 Hz frequency (M for Mayer wave), respiratory (R) and cardiac (C) rhythms with their harmonics. Enhanced baseline regional neural activity identified according to M and R peaks was found to be presumably sympathetic in pelvic pain patients, and parasympathetic – in patients with overactive bladder. Total pulsatile activity and pulsatile resonances found in the bladder as well as in the penile spectrum characterised regional circulation and vascular tone. The abnormal spectral parameters characteristic of the patients with genitourinary diseases shifted to the norm in the cases of efficient therapy. Bioimpedance harmonic analysis seems to be a potent tool to assess regional peculiarities of circulatory and autonomic nervous activity in the course of patient treatment.

Bioimpedance Harmonic Analysis as a Diagnostic Tool to Assess Regional Circulation and Neural Activity

Science.gov (United States)

Mudraya, I. S.; Revenko, S. V.; Khodyreva, L. A.; Markosyan, T. G.; Dudareva, A. A.; Ibragimov, A. R.; Romich, V. V.; Kirpatovsky, V. I.

2013-04-01

The novel technique based on harmonic analysis of bioimpedance microvariations with original hard- and software complex incorporating a high-resolution impedance converter was used to assess the neural activity and circulation in human urinary bladder and penis in patients with pelvic pain, erectile dysfunction, and overactive bladder. The therapeutic effects of shock wave therapy and Botulinum toxin detrusor injections were evaluated quantitatively according to the spectral peaks at low 0.1 Hz frequency (M for Mayer wave), respiratory (R) and cardiac (C) rhythms with their harmonics. Enhanced baseline regional neural activity identified according to M and R peaks was found to be presumably sympathetic in pelvic pain patients, and parasympathetic - in patients with overactive bladder. Total pulsatile activity and pulsatile resonances found in the bladder as well as in the penile spectrum characterised regional circulation and vascular tone. The abnormal spectral parameters characteristic of the patients with genitourinary diseases shifted to the norm in the cases of efficient therapy. Bioimpedance harmonic analysis seems to be a potent tool to assess regional peculiarities of circulatory and autonomic nervous activity in the course of patient treatment.

A Temperature-Based Bioimpedance Correction for Water Loss Estimation During Sports.

Science.gov (United States)

Ring, Matthias; Lohmueller, Clemens; Rauh, Manfred; Mester, Joachim; Eskofier, Bjoern M

2016-11-01

The amount of total body water (TBW) can be estimated based on bioimpedance measurements of the human body. In sports, TBW estimations are of importance because mild water losses can impair muscular strength and aerobic endurance. Severe water losses can even be life threatening. TBW estimations based on bioimpedance, however, fail during sports because the increased body temperature corrupts bioimpedance measurements. Therefore, this paper proposes a machine learning method that eliminates the effects of increased temperature on bioimpedance and, consequently, reveals the changes in bioimpedance that are due to TBW loss. This is facilitated by utilizing changes in skin and core temperature. The method was evaluated in a study in which bioimpedance, temperature, and TBW loss were recorded every 15 min during a 2-h running workout. The evaluation demonstrated that the proposed method is able to reduce the error of TBW loss estimation by up to 71%, compared to the state of art. In the future, the proposed method in combination with portable bioimpedance devices might facilitate the development of wearable systems for continuous and noninvasive TBW loss monitoring during sports.

Lower creatinine as a marker of malnutrition and lower muscle mass in hemodialysis patients

OpenAIRE

Yildiz A; Tufan F

2015-01-01

Abdulmecit Yildiz,1 Fatih Tufan2 1Department of Nephrology, Uludag University School of Medicine, Bursa, 2Department of Geriatrics, Istanbul Faculty of Medicine, Istanbul University, Istanbul, TurkeyWe read the recently published and well-designed study of Lee et al that suggests that bioimpedance analysis (BIA) gives relevant information about hydration status and malnutrition in hemodialysis patients. The authors recommend that utilization of BIA routinely in hemodialysis patients would be...

Preliminary bioelectrical impedance analysis (BIA) equation for body composition assessment in young females from Colombia

International Nuclear Information System (INIS)

Caicedo, J C; González-Correa, C H; González-Correa, C A

2013-01-01

A previous study showed that reported BIA equations for body composition are not suitable for Colombian population. The purpose of this study was to develop and validate a preliminary BIA equation for body composition assessment in young females from Colombia, using hydrodensitometry as reference method. A sample of 30 young females was evaluated. Inclusion and exclusion criteria were defined to minimize the variability of BIA. Height, weight, BIA, residual lung volume (RV) and underwater weight (UWW) were measured. A preliminary BIA equation was developed (r 2 = 0.72, SEE = 2.48 kg) by stepwise multiple regression with fat-free mass (FFM) as dependent variable and weight, height and impedance measurements as independent variables. The quality of regression was evaluated and a cross-validation against 50% of sample confirmed that results obtained with the preliminary BIA equation is interchangeable with results obtained with hydrodensitometry (r 2 = 0.84, SEE = 2.62 kg). The preliminary BIA equation can be used for body composition assessment in young females from Colombia until a definitive equation is developed. The next step will be increasing the sample, including a second reference method, as deuterium oxide dilution (D 2 O), and using multi-frequency BIA (MF-BIA). It would also be desirable to develop equations for males and other ethnic groups in Colombia.

A LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) for biological tissue impedance analysis and equivalent circuit modelling

KAUST Repository

Bera, Tushar Kanti

2016-12-05

Under an alternating electrical signal, biological tissues produce a complex electrical bioimpedance that is a function of tissue composition and applied signal frequencies. By studying the bioimpedance spectra of biological tissues over a wide range of frequencies, we can noninvasively probe the physiological properties of these tissues to detect possible pathological conditions. Electrical impedance spectroscopy (EIS) can provide the spectra that are needed to calculate impedance parameters within a wide range of frequencies. Before impedance parameters can be calculated and tissue information extracted, impedance spectra should be processed and analyzed by a dedicated software program. National Instruments (NI) Inc. offers LabVIEW, a fast, portable, robust, user-friendly platform for designing dataanalyzing software. We developed a LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) to analyze the electrical impedance spectra for tissue characterization in medical, biomedical and biological applications. Here, we test, calibrate and evaluate the performance of LEBISDI on the impedance data obtained from simulation studies as well as the practical EIS experimentations conducted on electronic circuit element combinations and the biological tissue samples. We analyze the Nyquist plots obtained from the EIS measurements and compare the equivalent circuit parameters calculated by LEBISDI with the corresponding original circuit parameters to assess the accuracy of the program developed. Calibration studies show that LEBISDI not only interpreted the simulated and circuitelement data accurately, but also successfully interpreted tissues impedance data and estimated the capacitive and resistive components produced by the compositions biological cells. Finally, LEBISDI efficiently calculated and analyzed variation in bioimpedance parameters of different tissue compositions, health and temperatures. LEBISDI can also be used for human tissue

A LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) for biological tissue impedance analysis and equivalent circuit modelling

KAUST Repository

Bera, Tushar Kanti; Jampana, Nagaraju; Lubineau, Gilles

2016-01-01

Under an alternating electrical signal, biological tissues produce a complex electrical bioimpedance that is a function of tissue composition and applied signal frequencies. By studying the bioimpedance spectra of biological tissues over a wide range of frequencies, we can noninvasively probe the physiological properties of these tissues to detect possible pathological conditions. Electrical impedance spectroscopy (EIS) can provide the spectra that are needed to calculate impedance parameters within a wide range of frequencies. Before impedance parameters can be calculated and tissue information extracted, impedance spectra should be processed and analyzed by a dedicated software program. National Instruments (NI) Inc. offers LabVIEW, a fast, portable, robust, user-friendly platform for designing dataanalyzing software. We developed a LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) to analyze the electrical impedance spectra for tissue characterization in medical, biomedical and biological applications. Here, we test, calibrate and evaluate the performance of LEBISDI on the impedance data obtained from simulation studies as well as the practical EIS experimentations conducted on electronic circuit element combinations and the biological tissue samples. We analyze the Nyquist plots obtained from the EIS measurements and compare the equivalent circuit parameters calculated by LEBISDI with the corresponding original circuit parameters to assess the accuracy of the program developed. Calibration studies show that LEBISDI not only interpreted the simulated and circuitelement data accurately, but also successfully interpreted tissues impedance data and estimated the capacitive and resistive components produced by the compositions biological cells. Finally, LEBISDI efficiently calculated and analyzed variation in bioimpedance parameters of different tissue compositions, health and temperatures. LEBISDI can also be used for human tissue

Intra-abdominal fat: Comparison of computed tomography fat segmentation and bioimpedance spectroscopy.

Science.gov (United States)

Finch, Peter

2017-06-01

Intra-abdominal fat is an important factor in determining the metabolic syndrome/insulin resistance, and thus the risk of diabetes and ischaemic heart disease. Computed Tomography (CT) fat segmentation represents a defined method of quantifying intra-abdominal fat, with attendant radiation risks. Bioimpedance spectroscopy may offer a method of assessment without any risks to the patients. A comparison is made of these two methods. This was a preliminary study of the utility of multifrequency bioimpedance spectroscopy of the mid abdomen as a measure of intra-abdominal fat, by comparison with fat segmentation of an abdominal CT scan in the -30 to -190 HU range. There was a significant (P abdominal fat and mid-upper arm circumference, as well as the bioimpedance parameter, the R/S ratio. Multivariate analysis showed that these were the only independant variables and allowed the derivation of a formula to estimate intra-abdominal fat: IAF = 0.02 × MAC - 0.757 × R/S + 0.036. Circumabdominal bioimpedance spectroscopy may prove a useful method of assessing intra-abdominal fat, and may be suitable for use in studies to enhance other measures of body composition, such as mid-upper arm circumference.

Assessment of nutritional status in adult patients with cystic fibrosis: whole-body bioimpedance vs body mass index, skinfolds, and leg-to-leg bioimpedance

NARCIS (Netherlands)

Hollander, F.M.; Roos, de N.M.; Vries, de J.H.M.; Berkhout, van F.T.

2005-01-01

Objective: To investigate whether body mass index (BMI) or body fat percentage estimated from BMI, skinfolds, or leg-to-leg bioimpedance are good indicators of nutritional status in adult patients with cystic fibrosis. Body fat percentage measured by whole-body bioimpedance was used as the reference

The validity and accuracy in foot-to-foot bioelectrical impedance ...

African Journals Online (AJOL)

owner

2011-04-18

Apr 18, 2011 ... impedance analysis measuring models referenced by dual-energy ... The ZF-F value was 481.85 ± 63.37 ohm in male and ... BIA method to predict the body composition such as ... position have been published, the comparison of various ..... Bioimpedance analysis: evaluation of leg-to-leg system based.

Impact of demographic, genetic, and bioimpedance factors on gestational weight gain and birth weight in a Romanian population

Science.gov (United States)

Mărginean, Claudiu; Mărginean, Cristina Oana; Bănescu, Claudia; Meliţ, Lorena; Tripon, Florin; Iancu, Mihaela

2016-01-01

Abstract The present study had 2 objectives, first, to investigate possible relationships between increased gestational weight gain and demographic, clinical, paraclinical, genetic, and bioimpedance (BIA) characteristics of Romanian mothers, and second, to identify the influence of predictors (maternal and newborns characteristics) on our outcome birth weight (BW). We performed a cross-sectional study on 309 mothers and 309 newborns from Romania, divided into 2 groups: Group I—141 mothers with high gestational weight gain (GWG) and Group II—168 mothers with normal GWG, that is, control group. The groups were evaluated regarding demographic, anthropometric (body mass index [BMI], middle upper arm circumference, tricipital skinfold thickness, weight, height [H]), clinical, paraclinical, genetic (interleukin 6 [IL-6]: IL-6 -174G>C and IL-6 -572C>G gene polymorphisms), and BIA parameters. We noticed that fat mass (FM), muscle mass (MM), bone mass (BM), total body water (TBW), basal metabolism rate (BMR) and metabolic age (P mothers with high GWG. BW was positively correlated with mothers’ FM (P G polymorphism was higher in the control group (P = 0.042). We observed that high GWG may be an important predictor factor for the afterward BW, being positively correlated with FM, TBW, BMR, metabolic age of the mothers, and negatively with the mother's smoking status. Variant genotype (GG+GC) of the IL-6 -572C>G gene polymorphism is a protector factor against obesity in mothers. All the variables considered explained 14.50% of the outcome variance. PMID:27399105

A Comparison of Methods for the Estimation of Body Composition in Highly Trained Wheelchair Games Players

NARCIS (Netherlands)

Goosey-Tolfrey, V.; Keil, M.; Brooke-Wavell, K.; de Groot, S.

The purpose of this study was to assess the agreement in body composition measurements of wheelchair athletes using skinfolds, bio-impedance analysis (BIA) and air displacement plethysmography (ADP) relative to dual-energy X-ray absorptiometry (DXA). A secondary objective was to develop new skinfold

The French National Authority for Health (HAS) Guidelines for Conducting Budget Impact Analyses (BIA).

Science.gov (United States)

Ghabri, Salah; Autin, Erwan; Poullié, Anne-Isabelle; Josselin, Jean Michel

2018-04-01

Budget impact analysis (BIA) provides short- and medium-term estimates on changes in budgets and health outcomes resulting from the adoption of new health interventions. The purpose of this study is to present the newly developed French National Authority for Health (HAS) guidelines on budget impact analysis as follows: process, literature review, recommendations and comparisons with other guidelines. The development process of the HAS guidelines included a literature review (search dates: January 2000 to June 2016), a retrospective investigation of BIA previously submitted to HAS, a public consultation, international expert reviews and approval from the HAS Board and the Economic and Public Health Evaluation Committee of HAS. Documents identified in the literature review included 12 national guidelines, 5 recommendations for good practices developed by national and international society of health economics and 14 methodological publications including recommendations for conducting BIA. Based on its research findings, HAS developed its first BIA guidelines, which include recommendations on the following topics: BIA definition, perspective, populations, time horizon, compared scenarios, budget impact models, costing, discounting, choice of clinical data, reporting of results and uncertainty exploration. It is expected that the HAS BIA guidelines will enhance the usefulness, quality and transparency of BIA submitted by drug manufacturers to HAS. BIA is becoming an essential part of a comprehensive economic assessment of healthcare interventions in France, which also includes cost-effectiveness analysis and equity of access to healthcare.

Bioimpedance measurement based evaluation of wound healing.

Science.gov (United States)

Kekonen, Atte; Bergelin, Mikael; Eriksson, Jan-Erik; Vaalasti, Annikki; Ylänen, Heimo; Viik, Jari

2017-06-22

Our group has developed a bipolar bioimpedance measurement-based method for determining the state of wound healing. The objective of this study was to assess the capability of the method. To assess the performance of the method, we arranged a follow-up study of four acute wounds. The wounds were measured using the method and photographed throughout the healing process. Initially the bioimpedance of the wounds was significantly lower than the impedance of the undamaged skin, used as a baseline. Gradually, as healing progressed, the wound impedance increased and finally reached the impedance of the undamaged skin. The clinical appearance of the wounds examined in this study corresponded well with the parameters derived from the bioimpedance data. Hard-to-heal wounds are a significant and growing socioeconomic burden, especially in the developed countries, due to aging populations and to the increasing prevalence of various lifestyle related diseases. The assessment and the monitoring of chronic wounds are mainly based on visual inspection by medical professionals. The dressings covering the wound must be removed before assessment; this may disturb the wound healing process and significantly increases the work effort of the medical staff. There is a need for an objective and quantitative method for determining the status of a wound without removing the wound dressings. This study provided evidence of the capability of the bioimpedance based method for assessing the wound status. In the future measurements with the method should be extended to concern hard-to-heal wounds.

Resting energy expenditure and body composition in children with cancer: indirect calorimetry and bioimpedance analysis

Directory of Open Access Journals (Sweden)

M. V. Konovalova

2014-07-01

Full Text Available Resting energy expenditure (REE by indirect calorimetry and body composition by bioimpedance analysis are studied in three groups of children aged 5–18 years. Group 1 (n = 181 – patients in remission of cancer, group 2 (n = 55 – children with oncology diseases receiving chemotherapy or who are in the early period after hematopoietic stem cell transplantation, group 3 (n = 63 – children with non-malignant diseases of the gastrointestinal tract. To eliminate the influence of age and gender on the intergroup comparisons, body composition parameters were expressed as standardized values (z-scores relative to a reference group of healthy Russian children (n = 138,191. Group 1 was characterized by excess fat content with intact lean body mass, and groups 2 and 3 by protein depletion, more pronounced in Group 2 with a higher percentage of body fat. All used conventional formulas (WHO, Harris–Benedict and others in groups 1 and 3 underestimated REE as compared with indirect calorimetry. A new formula for REE, giving an unbiased estimate in the group 1 was proposed: REE (kcal/day = 28.7 × BCM (kg +10.5 × Height (cm – 38.6 × Age (years – 134, where BCM – body cell mass according to bioimpedance analysis (R2 = 0.67, the standard deviation of 196 kcal/day.

Bioimpedance measurement of body water correlates with measured volume balance in injured patients.

Science.gov (United States)

Rosemurgy, A S; Rodriguez, E; Hart, M B; Kurto, H Z; Albrink, M H

1993-06-01

Bioimpedance technology is being used increasingly to determine drug volume of distribution, body water status, and nutrition repletion. Its accuracy in patients experiencing large volume flux is not established. To address this, we undertook this prospective study in 54 consecutive seriously injured adults who had emergency celiotomy soon after arrival in the emergency department. Bioimpedance measurements were obtained in the emergency department before the patient was transported to the operating room, on completion of celiotomy, and 24 hours and 48 hours after celiotomy. Bioimpedance measurements of body water were compared with measured fluid balance. If insensible losses are subtracted from measured fluid balance, the percentage of body weight, which is body water determined by bioimpedance, closely follows fluid flux. This study supports the use of bioimpedance measurements in determining total body water even during periods of surgery, blood loss, and vigorous resuscitation.

Change in fat-free mass assessed by bioelectrical impedance, total body potassium and dual energy X-ray absorptiometry during prolonged weight loss

DEFF Research Database (Denmark)

Hendel, H W; Gotfredsen, A; Højgaard, L

1996-01-01

). These measurements were compared with bioimpedance analysis (BIA) by applying 11 predictive BIA equations published in the literature. Predictive equations for the present study population were developed, with the use of fat-free mass (FFM) as assessed by TBK and DXA as references in multiple regression analysis....... The results of the BIA equations varied widely; FFM was generally overestimated by BIA as compared with DXA and TBK before and after weight loss. During weight loss, the FFM did not change, as estimated by DXA (1.3 +/- 2.3 kg, p > 0.05) and TBK (0.9 +/- 2.9 kg, p > 0.05). The recorded change in impedance (R......) was also insignificant. Three BIA equations from the literature, which were not specific for the degree of obesity in the present study group, predicted changes in FFM (from 0.5 + 3.6 to 2.4 +/- 4.4kg, p > 0.05) that were comparable with those estimated by the reference methods. Eight equations from...

Multi-frequency bioimpedance in equine muscle assessment

DEFF Research Database (Denmark)

Harrison, Adrian Paul; Elbrønd (Bibs), Vibeke Sødring; Riis-Olesen, Kiwa

2015-01-01

BIA reliably can be used to assess the condition of a horse's muscles in connection with health assessment, injury and both training and re-training. mfBIA measurements was carried out on 10 'hobby' horses and 5 selected cases with known anamnesis. Impedance, resistance, reactance, phase angle, centre...

Cell growth characterization using multi-electrode bioimpedance spectroscopy

International Nuclear Information System (INIS)

Lu, Yi-Yu; Huang, Yu-Jie; Cheng, Kuo-Sheng; Huang, Ji-Jer

2013-01-01

Cell growth characterization during culturing is an important issue in a variety of biomedical applications. In this study an electrical bioimpedance spectroscopy-based multi-electrode culture monitoring system was developed to characterize cell growth. A PC12 cell line was cultured for the cell growth study. The bioimpedance variations for PC12 cell growth within the initial 12 h were measured over a range between 1 kHz and 4 MHz at three different medium concentrations. Within this frequency range, the largest bioimpedance value was 1.9 times the smallest bioimpedance value. The phase angle decreased over the range from 1 to 10 kHz when cells were growing. Then, the phase angle approached a constant over the frequency range between 10 kHz and 2 MHz. Thereafter, the phase angle increased rapidly from 20 to 52 degrees during cell culturing between 8 and 12 h at 4 MHz. The maximum cell number after culturing for 12 h increased by 25.8% for the control sites with poly-D-lysine (PDL) pastes. For the normal growth factor, the cell number increased up to 4.78 times from 8 to 12 h, but only 0.96 and 1.60 times for the other two medium growth factors. The correlation coefficients between impedance and cell number were 0.868 (coating with PDL), and 0.836 (without PDL) for the normal concentration medium. Thus, impedance may be used as an index for cell growth characterization. (paper)

Perspectives on clinical use of bioimpedance in hemodialysis: focus group interviews with renal care professionals.

Science.gov (United States)

Stenberg, Jenny; Henriksson, Catrin; Lindberg, Magnus; Furuland, Hans

2018-05-23

Inadequate volume control may be a main contributor to poor survival and high mortality in hemodialysis patients. Bioimpedance measurement has the potential to improve fluid management, but several dialysis centers lack an agreed fluid management policy, and the method has not yet been implemented. Our aim was to identify renal care professionals' perceived barriers and facilitators for use of bioimpedance in clinical practice. Qualitative data were collected through four focus group interviews with 24 renal care professionals: dieticians, nephrologists and nurses, recruited voluntarily from a nation-wide selection of hemodialysis centers, having access to a bioimpedance-device. The participants were connected to each other and a moderator via equipment for telemedicine and the sessions were recorded. The interviews were semi-structured, focusing on the participants' perceptions of use of bioimpedance in clinical practice. Thematic content analysis was performed in consecutive steps, and data were extracted by employing an inductive, interactive, comparative process. Several barriers and facilitators to the use of bioimpedance in clinical practice were identified, and a multilevel approach to examining barriers and incentives for change was found to be applicable to the ideas and categories that arose from the data. The determinants were categorized on five levels, and the different themes of the levels illustrated with quotations from the focus groups participants. Determinants for use of bioimpedance were identified on five levels: 1) the innovation itself, 2) the individual professional, 3) the patient, 4) the social context and 5) the organizational context. Barriers were identified in the areas of credibility, awareness, knowledge, self-efficacy, care processes, organizational structures and regulations. Facilitators were identified in the areas of the innovation's attractiveness, advantages in practice, and collaboration. Motivation, team processes and

Lower creatinine as a marker of malnutrition and lower muscle mass in hemodialysis patients

Directory of Open Access Journals (Sweden)

Yildiz A

2015-10-01

Full Text Available Abdulmecit Yildiz,1 Fatih Tufan2 1Department of Nephrology, Uludag University School of Medicine, Bursa, 2Department of Geriatrics, Istanbul Faculty of Medicine, Istanbul University, Istanbul, TurkeyWe read the recently published and well-designed study of Lee et al that suggests that bioimpedance analysis (BIA gives relevant information about hydration status and malnutrition in hemodialysis patients. The authors recommend that utilization of BIA routinely in hemodialysis patients would be rational. We would like to make a few comments about their study.View original paper by Lee et al.

Screening for pre-eclampsia in the first trimester: role of maternal hemodynamics and bioimpedance in non-obese patients.

Science.gov (United States)

Gagliardi, G; Tiralongo, G M; LoPresti, D; Pisani, I; Farsetti, D; Vasapollo, B; Novelli, G P; Andreoli, A; Valensise, H

2017-11-01

To test if maternal hemodynamics and bioimpedance, assessed at the time of combined screening for PE, are able to identify in the first trimester of gestation normotensive non-obese patients at risk for pre-eclampsia (PE) and/or intrauterine growth restriction (IUGR). One hundred and fifty healthy nulliparous non-obese women (body mass index < 30 kg/m 2 ) in the first trimester of pregnancy underwent assessment by UltraSonic Cardiac Output Monitor (USCOM) to detect hemodynamic parameters, bioimpedance analysis to characterize body composition, and combined screening for PE (assessment of maternal history, biophysical and maternal biochemical markers). Patients were followed until term, noting the appearance of PE and/or IUGR. One hundred and thirty-eight patients had an uneventful pregnancy (controls), while 12 (8%) developed complications (cases). USCOM showed, in cases compared with controls, lower cardiac output (5.6 ± 0.3 vs 6.7 ± 1.1 L/min, P < 0.001), lower inotropy index (1.54 ± 0.38 vs 1.91 ± 0.32 W/m 2 , P < 0.001) and higher total vascular resistance (1279.8 ± 166.4 vs 1061.4 ± 179.5 dynes × s/cm 5 , P < 0.001). Bioimpedance analysis showed, in cases compared with controls, lower total body water (53.7 ± 3.3% vs 57.2 ± 5.6%, P = 0.037). Combined screening was positive for PE in 8% of the controls and in 50% of the cases (P < 0.001). After identification of cut-off values for USCOM and bioimpedance parameters, forward multivariate logistic regression analysis identified as independent predictors of complications in pregnancy the inotropy index (derived by USCOM), fat mass (derived from bioimpedance analysis) and combined screening. Combined screening for PE and assessment of bioimpedance and maternal hemodynamics can be used to identify early markers of impaired cardiovascular adaptation and body composition that may lead to complications in the third trimester of pregnancy. Copyright �

Funkcje białek bakteriofagowych

Directory of Open Access Journals (Sweden)

Ewa Brzozowska

2011-01-01

Full Text Available Bakteriofagi (fagi stanowią naturalny czynnik regulujący liczebność populacji bakteryjnych w przyrodzie. Zainteresowanie bakteriofagami ciągle wzrasta ze względu na ich ogromną liczebność w naturalnym środowisku, a tym samym wpływ na funkcjonowanie organizmów żywych oraz zastosowanie w terapii przeciwko patogennym bakteriom opornym na stosowane antybiotyki. Za swoistość i za zjadliwość fagów wobec bakterii odpowiadają białka wchodzące w skład cząstki fagowej. Białkami tymi są adhezyny rozpoznające receptory na komórkach gospodarzy oraz enzymy degradujące określone struktury ściany komórkowej lub otoczki bakterii. Inne białka fagowe pełnią funkcję strukturalną, wchodząc w skład kapsydów. Białka te chronią fagowy kwas nukleinowy oraz umożliwiają przekazanie wirusowego genomu do wnętrza komórki bakteryjnej, a tym samym odpowiadają za proces infekcji i namnażania fagów potomnych. Enzymy fagowe są ważną grupą białek, które degradują struktury ścian i otoczek bakteryjnych od zewnętrznej, a także od wewnętrznej strony komórki gospodarza. Są to enzymy lityczne hydrolizujące komponenty cukrowe oraz białkowe. Bliższe poznanie natury bakteriofagów oraz pojawienie się lekooporności wśród patogennych bakterii, spowodowało wzrost zainteresowania fagami, jako czynnikami leczniczymi. Bakteriofagi coraz częściej wykorzystywane są także w innych dziedzinach życia człowieka. Testowano je nie tylko w terapii roślin, zwierząt i ludzi, ale także zaproponowano ich użycie do odkażania żywności i środowiska.

25 CFR 170.801 - What is the BIA Road Maintenance Program?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is the BIA Road Maintenance Program? 170.801 Section... ROADS PROGRAM BIA Road Maintenance § 170.801 What is the BIA Road Maintenance Program? The BIA Road... subpart contains a list of activities that are eligible for funding under the BIA road maintenance program. ...

Role of bioimpedance vectorial analysis in cardio-renal syndromes.

Science.gov (United States)

Aspromonte, Nadia; Cruz, Dinna N; Ronco, Claudio; Valle, Roberto

2012-01-01

The cardio-renal syndromes (CRS) are the result of complex bidirectional organ cross-talk between the heart and kidney, with tremendous overlap of diseases such as coronary heart disease, heart failure (HF), and renal dysfunction in the same patient. Volume overload plays an important role in the pathophysiology of CRS. The appropriate treatment of overhydration, particularly in HF and in chronic kidney disease, has been associated with improved outcomes and blood pressure control. Clinical examination alone is often insufficient for accurate assessment of volume status because significant volume overload can exist even in the absence of peripheral or pulmonary edema on physical examination or radiography. Bioelectrical impedance techniques increasingly are being used in the management of patients with HF and those on chronic dialysis. These methods provide more objective estimates of volume status in such patients. Used in conjunction with standard clinical assessment and biomarkers such as the natriuretic peptides, bioimpedance analysis may be useful in guiding pharmacologic and ultrafiltration therapies and subsequently restoring such patients to a euvolemic or optivolemic state. In this article, we review the use of these techniques in CRS. Copyright © 2012 Elsevier Inc. All rights reserved.

Bio-impedance analysis for appendicular skeletal muscle mass assessment in (pre-) frail elderly people

NARCIS (Netherlands)

Baar, van H.; Hulshof, P.J.M.; Tieland, C.A.B.; Groot, de C.P.G.M.

2015-01-01

Background & aims Screening populations for skeletal muscle mass (SMM) is important for early detection of sarcopenia. Our aim was to develop an age specific bio-impedance (BI) prediction equation for the assessment of appendicular skeletal muscle mass (ASMM) in (pre-) frail elderly people aged

Estimation of normal hydration in dialysis patients using whole body and calf bioimpedance analysis.

Science.gov (United States)

Zhu, Fansan; Kotanko, Peter; Handelman, Garry J; Raimann, Jochen G; Liu, Li; Carter, Mary; Kuhlmann, Martin K; Seibert, Eric; Leonard, Edward F; Levin, Nathan W

2011-07-01

Prescription of an appropriate dialysis target weight (dry weight) requires accurate evaluation of the degree of hydration. The aim of this study was to investigate whether a state of normal hydration (DW(cBIS)) as defined by calf bioimpedance spectroscopy (cBIS) and conventional whole body bioimpedance spectroscopy (wBIS) could be characterized in hemodialysis (HD) patients and normal subjects (NS). wBIS and cBIS were performed in 62 NS (33 m/29 f) and 30 HD patients (16 m/14 f) pre- and post-dialysis treatments to measure extracellular resistance and fluid volume (ECV) by the whole body and calf bioimpedance methods. Normalized calf resistivity (ρ(N)(,5)) was defined as resistivity at 5 kHz divided by the body mass index. The ratio of wECV to total body water (wECV/TBW) was calculated. Measurements were made at baseline (BL) and at DW(cBIS) following the progressive reduction of post-HD weight over successive dialysis treatments until the curve of calf extracellular resistance is flattened (stabilization) and the ρ(N)(,5) was in the range of NS. Blood pressures were measured pre- and post-HD treatment. ρ(N)(,5) in males and females differed significantly in NS. In patients, ρ(N)(,5) notably increased with progressive decrease in body weight, and systolic blood pressure significantly decreased pre- and post-HD between BL and DW(cBIS) respectively. Although wECV/TBW decreased between BL and DW(cBIS), the percentage of change in wECV/TBW was significantly less than that in ρ(N)(,5) (-5.21 ± 3.2% versus 28 ± 27%, p hydration between BL and DW(cBIS).

DXA, bioelectrical impedance, ultrasonography and biometry for the estimation of fat and lean mass in cats during weight loss

Directory of Open Access Journals (Sweden)

Borges Naida C

2012-07-01

Full Text Available Abstract Background Few equations have been developed in veterinary medicine compared to human medicine to predict body composition. The present study was done to evaluate the influence of weight loss on biometry (BIO, bioimpedance analysis (BIA and ultrasonography (US in cats, proposing equations to estimate fat (FM and lean (LM body mass, as compared to dual energy x-ray absorptiometry (DXA as the referenced method. For this were used 16 gonadectomized obese cats (8 males and 8 females in a weight loss program. DXA, BIO, BIA and US were performed in the obese state (T0; obese animals, after 10% of weight loss (T1 and after 20% of weight loss (T2. Stepwise regression was used to analyze the relationship between the dependent variables (FM, LM determined by DXA and the independent variables obtained by BIO, BIA and US. The better models chosen were evaluated by a simple regression analysis and means predicted vs. determined by DXA were compared to verify the accuracy of the equations. Results The independent variables determined by BIO, BIA and US that best correlated (p r2, 19 equations were selected (12 for FM, 7 for LM; however, only 7 equations accurately predicted FM and one LM of cats. Conclusions The equations with two variables are better to use because they are effective and will be an alternative method to estimate body composition in the clinical routine. For estimated lean mass the equations using body weight associated with biometrics measures can be proposed. For estimated fat mass the equations using body weight associated with bioimpedance analysis can be proposed.

Tekst (dźwiękowy Mirona Białoszewskiego

Directory of Open Access Journals (Sweden)

Andrzej Hejmej

2007-08-01

Full Text Available The paper focuses on the interaction between the visual text and sound-text in the works of Miron Białoszewski, especially in his Separate Theatre. In this case, considerations on the subject of textuality show a relation between Białoszewskim linguistics experiments and contemporary sound poetry. In essence, the sound poetry as an artistic practice (particularly, the sound poetry of Bernard Heidsieck appears to be an important and inspiring context for interpretation of Białoszewskim text. Finally, based on the problem of sound-text, many similarities are found between Miron Białoszewski and Bernard Heidsieck.

A Thorax Simulator for Complex Dynamic Bioimpedance Measurements With Textile Electrodes.

Science.gov (United States)

Ulbrich, Mark; Muhlsteff, Jens; Teichmann, Daniel; Leonhardt, Steffen; Walter, Marian

2015-06-01

Bioimpedance measurements on the human thorax are suitable for assessment of body composition or hemodynamic parameters, such as stroke volume; they are non-invasive, easy in application and inexpensive. When targeting personal healthcare scenarios, the technology can be integrated into textiles to increase ease, comfort and coverage of measurements. Bioimpedance is generally measured using two electrodes injecting low alternating currents (0.5-10 mA) and two additional electrodes to measure the corresponding voltage drop. The impedance is measured either spectroscopically (bioimpedance spectroscopy, BIS) between 5 kHz and 1 MHz or continuously at a fixed frequency around 100 kHz (impedance cardiography, ICG). A thorax simulator is being developed for testing and calibration of bioimpedance devices and other new developments. For the first time, it is possible to mimic the complete time-variant properties of the thorax during an impedance measurement. This includes the dynamic real part and dynamic imaginary part of the impedance with a peak-to-peak value of 0.2 Ω and an adjustable base impedance (24.6 Ω ≥ Z0 ≥ 51.6 Ω). Another novelty is adjustable complex electrode-skin contact impedances for up to 8 electrodes to evaluate bioimpedance devices in combination with textile electrodes. In addition, an electrocardiographic signal is provided for cardiographic measurements which is used in ICG devices. This provides the possibility to generate physiologic impedance changes, and in combination with an ECG, all parameters of interest such as stroke volume (SV), pre-ejection period (PEP) or extracellular resistance (Re) can be simulated. The speed of all dynamic signals can be altered. The simulator was successfully tested with commercially available BIS and ICG devices and the preset signals are measured with high correlation (r = 0.996).

Predicting burst pressure of radiofrequency-induced colorectal anastomosis by bio-impedance measurement.

Science.gov (United States)

Zhao, Lingxi; Zhou, Yu; Song, Chengli; Wang, Zhigang; Cuschieri, Alfred

2017-03-01

The present study investigates the relationship between bio-impedance and burst pressure of colorectal anastomosis created by radiofrequency (RF)-induced tissue fusion. Colorectal anastomosis were created with ex vivo porcine colorectal segments, during which 5 levels of compression pressure were applied by a custom-made bipolar prototype, with 5 replicate experiments at each compression pressure. Instant anastomotic tensile strength was assessed by burst pressure. Bio-impedance of fused tissue was measured by Impedance Analyzer across frequency that 100 Hz to 3 MHz. Statistical analysis shows only a weak correlation between bio-impedance modulus and burst pressures at frequency of 445 kHz ([Formula: see text]  =  -0.426, P  =  0.099  >  0.05). In contrast, results demonstrated a highly significant negative correlation between reactance modulus and burst pressures ([Formula: see text]  =  -0.812, P  =  0.000  <  0.05). The decrease in mean reactance modulus with increasing burst pressures was highly significant (P  =  0.019  <  0.05). The observed strong negative correlation between reactance modulus and burst pressures at frequency of 445 kHz indicates that reactance is likely to be a good index for tensile strength of RF-induced colorectal anastomosis, and should be considered for inclusion in a feedback loops in devices design.

Optimum conductive fabric sensor sites for evaluating the status of knee joint movements using bio-impedance

Directory of Open Access Journals (Sweden)

Kim Jinkwon

2011-06-01

Full Text Available Abstract Background There have been many studies that utilize the bio-impedance measurement method to analyze the movements of the upper and lower limbs. A fixed electrical current flows into the limbs through four standard disposable electrodes in this method. The current flows in the muscles and blood vessels, which have relatively low resistivity levels in the human body. This method is used to measure bio-impedance changes following volume changes of muscles and blood vessels around a knee joint. The result of the bio-impedance changes is used to evaluate the movements. However, the method using the standard disposable electrodes has a restriction related to its low bio-impedance changes: the standard disposable electrodes are only able to measure bio-impedance from a limited part of a muscle. Moreover, it is impossible to use continuously, as the electrodes are designed to be disposable. This paper describes a conductive fabric sensor (CFS using a bio-impedance measurement method and determines the optimum configuration of the sensor for estimating knee joint movements. Methods The upper side of subjects' lower limbs was divided into two areas and the lower side of subjects' lower limbs was divided into three areas. The spots were matched and 6 pairs were selected. Subjects were composed of 15 males (age: 30.7 ± 5.3, weight: 69.8 ± 4.2 kg, and height: 173.5 ± 2.8 cm with no known problems with their knee joints. Bio-impedance changes according to knee joint flexion/extension assessments were calculated and compared with bio-impedance changes by an ankle joint flexion/extension test (SNR I and a hip joint flexion/extension test (SNR II. Results The bio-impedance changes of the knee joint flexion/extension assessment were 35.4 ± 20.0 Ω on the (1, 5 pair. SNR I was 3.8 ± 8.4 and SNR II was 6.6 ± 7.9 on the (1, 5 pair. Conclusions The optimum conductive fabric sensor configuration for evaluating knee joint movements were represented by

Bioelectrical impedance and visceral fat: a comparison with computed tomography in adults and elderly

International Nuclear Information System (INIS)

Eickemberg, Michaela; Roriz, Anna Karla Carneiro; Fontes, Gardenia Abreu Vieira; Sampaio, Lilian Ramos

2013-01-01

Objective: To evaluate the association between electrical bioimpedance analysis (BIA) and visceral fat (VF) in adult and elderly patients. Subjects and methods: This was a cross-sectional study, with a sample of 191 subjects (52% women, 49% elderly) stratified by sex, age and body mass. Computerized tomography (VF area) and BIA (percentage of total body fat (%TBF-BIA), phase angle, reactance and resistance) data were generated. Statistical analysis was based on Pearson's Correlation Coefficient, Anova, Pearson's Chi-square, and ROC curves. Results: VF areas ≥ 130 cm 2 were more prevalent among the elderly and among men. Adult females showed a stronger correlation between GV and %TBF-BIA. The other groups showed similar results and statistically significant correlations. Correlations between GV and phase angle were weak and not statistically significant. ROC Curves analyzes showed the following %TBF-BIA, which identified excess VF: for male subjects: 21.5% (adults) and 24.25% (elderly); for female subjects: 35.05% (adults) and 38.45% (elderly) with sensitivity of 78.6%, 82.1%, 83.3%, and 66.7%, and specificity of 70.6%, 62.5%, 79.1%, and 69%, respectively. Conclusion: BIA was found to have satisfactory sensitivity and specificity to predict VF; however, other devices and other techniques should be investigated to improve VF prediction. (author)

Bioelectrical impedance and visceral fat: a comparison with computed tomography in adults and elderly; Bioimpedancia eletrica e gordura visceral: uma comparacao com a tomografia computadorizada em adultos e idosos

Energy Technology Data Exchange (ETDEWEB)

Eickemberg, Michaela [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Roriz, Anna Karla Carneiro [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Fontes, Gardenia Abreu Vieira [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Sampaio, Lilian Ramos [Universidade Federal de Sao Paulo (Unifesp), Sao Paulo, SP (Brazil)

2013-05-01

Objective: To evaluate the association between electrical bioimpedance analysis (BIA) and visceral fat (VF) in adult and elderly patients. Subjects and methods: This was a cross-sectional study, with a sample of 191 subjects (52% women, 49% elderly) stratified by sex, age and body mass. Computerized tomography (VF area) and BIA (percentage of total body fat (%TBF-BIA), phase angle, reactance and resistance) data were generated. Statistical analysis was based on Pearson's Correlation Coefficient, Anova, Pearson's Chi-square, and ROC curves. Results: VF areas {>=} 130 cm{sup 2} were more prevalent among the elderly and among men. Adult females showed a stronger correlation between GV and %TBF-BIA. The other groups showed similar results and statistically significant correlations. Correlations between GV and phase angle were weak and not statistically significant. ROC Curves analyzes showed the following %TBF-BIA, which identified excess VF: for male subjects: 21.5% (adults) and 24.25% (elderly); for female subjects: 35.05% (adults) and 38.45% (elderly) with sensitivity of 78.6%, 82.1%, 83.3%, and 66.7%, and specificity of 70.6%, 62.5%, 79.1%, and 69%, respectively. Conclusion: BIA was found to have satisfactory sensitivity and specificity to predict VF; however, other devices and other techniques should be investigated to improve VF prediction. (author)

Can bioimpedance determine the volume of distribution of antibiotics in sepsis?

Science.gov (United States)

Balik, M; Sedivy, J; Waldauf, P; Kolar, M; Smejkalova, V; Pachl, J

2005-06-01

The relationship between the volume of distribution, assessed according to the two-compartmental pharmacokinetic model, and extracellular water estimated by bioimpedance was studied in mechanically ventilated patients with sepsis and capillary leak. A prospective observational study was performed in a twenty-bed general intensive care unit in the university hospital. Patients received either vancomycin (n = 16) or netilmicin (n = 12) for more than 48 hours. Those with ascites, pleural effusion, on renal replacement therapy or with haemodynamic instability were excluded. Serum concentrations of drugs were taken for pharmacokinetic analysis before, 1 hour and 4 hours after the 30 minute infusion. Bioimpedance measurement was performed at the time of the third sampling. The protocol was repeated after 24 hours. Fluid balance during the 24 hour interval was recorded. Extracellular water was increased and represented 45.6 to 46.6% of total body water Fluid balance correlated with the change of extracellular water (r = 0.82, P body water (r = 0.74, P water/total body ratio (r = 0.70, P water/total body water ratio (r = 0.60, P antibiotics.

Estimation of normal hydration in dialysis patients using whole body and calf bioimpedance analysis

International Nuclear Information System (INIS)

Zhu, Fansan; Kotanko, Peter; Handelman, Garry J; Raimann, Jochen G; Liu, Li; Carter, Mary; Kuhlmann, Martin K; Seibert, Eric; Levin, Nathan W; Leonard, Edward F

2011-01-01

Prescription of an appropriate dialysis target weight (dry weight) requires accurate evaluation of the degree of hydration. The aim of this study was to investigate whether a state of normal hydration (DW cBIS ) as defined by calf bioimpedance spectroscopy (cBIS) and conventional whole body bioimpedance spectroscopy (wBIS) could be characterized in hemodialysis (HD) patients and normal subjects (NS). wBIS and cBIS were performed in 62 NS (33 m/29 f) and 30 HD patients (16 m/14 f) pre- and post-dialysis treatments to measure extracellular resistance and fluid volume (ECV) by the whole body and calf bioimpedance methods. Normalized calf resistivity (ρ N,5 ) was defined as resistivity at 5 kHz divided by the body mass index. The ratio of wECV to total body water (wECV/TBW) was calculated. Measurements were made at baseline (BL) and at DW cBIS following the progressive reduction of post-HD weight over successive dialysis treatments until the curve of calf extracellular resistance is flattened (stabilization) and the ρ N,5 was in the range of NS. Blood pressures were measured pre- and post-HD treatment. ρ N,5 in males and females differed significantly in NS. In patients, ρ N,5 notably increased with progressive decrease in body weight, and systolic blood pressure significantly decreased pre- and post-HD between BL and DW cBIS respectively. Although wECV/TBW decreased between BL and DW cBIS , the percentage of change in wECV/TBW was significantly less than that in ρ N,5 (−5.21 ± 3.2% versus 28 ± 27%, p < 0.001). This establishes the use of ρ N,5 as a new comparator allowing a clinician to incrementally monitor removal of extracellular fluid from patients over the course of dialysis treatments. The conventional whole body technique using wECV/TBW was less sensitive than the use of ρ N,5 to measure differences in body hydration between BL and DW cBIS

Morphotectonic control of the Białka drainage basin (Central Carpathians: Insights from DEM and morphometric analysis.

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Wołosiewicz Bartosz

2016-06-01

Full Text Available The Białka river valley is directly related to a deep NNW-SSE oriented fault zone. According to the results of previous morphometric analyses, the Białka drainage basin is one of the most tectonically active zones in the Central Carpathians. It is also located within an area of high seismic activity.

Bioimpedance and chronoamperometry as an adjunct to prostate-specific antigen screening for prostate cancer

Directory of Open Access Journals (Sweden)

Abreu DS

2011-04-01

Full Text Available Darci Schiavon de AbreuDepartment of Urology, Hospital Unimed de Limeira, Sao Paulo, BrazilBackground: Bioimpedance is an electrical property of living tissue that has been shown to be a safe technique when used in a number of biomedical applications. The aim of this research was to assess the utility of bioimpedance measurement as a rapid, cost-effective, and noninvasive adjunct to digital rectal examination and PSA in differentiating tumor from normal prostatic tissue.Methods: Three hundred men were examined for signs and symptoms of prostate disorders. 147 patients with a digital rectal examination indicating a positive result underwent a prostate-specific antigen (PSA test. A biopsy was advised for 103 of the men, of whom 50 completed the study. Before undergoing biopsy, an examination with the EIS (electro interstitial scan system using bioimpedance and chronoamperometry was performed. In reference to the biopsy results (negative or positive, a statistical analysis of the EIS data and PSA was conducted using receiver operating characteristic curves to determine the specificity and sensitivity of each test.Results: The PSA test had a sensitivity of 73.9% and specificity of 51.9% using a cutoff value >4 and a sensitivity of 52.2% and specificity of 81.5% using a cutoff value ≥5.7 and P = 0.03. The delta of the electrical conductivity (DE of the left foot-right foot pathway had a sensitivity of 62.5% and specificity of 85.2%, with a cutoff value ≤-5 and P = 0.0001. Algorithms comprising the delta of electrical conductivity and PSA showed a sensitivity of 91.5% and a specificity of 59.3%, with a cutoff value ≤-10.52 and P = 0.0003.Conclusion: The EIS system had a very good specificity of 85.2%. However, the sensitivity of 62.5% would be a problem. Using a PSA reference >4.1 ng/mL, the adjunctive use of bioimpedance and chronoamperometry provided by EIS technology could raise the sensitivity from 73.9% to 91.5% and the specificity from 51

Galvanically Decoupled Current Source Modules for Multi-Channel Bioimpedance Measurement Systems

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Roman Kusche

2017-10-01

Full Text Available Bioimpedance measurements have become a useful technique in the past several years in biomedical engineering. Especially, multi-channel measurements facilitate new imaging and patient monitoring techniques. While most instrumentation research has focused on signal acquisition and signal processing, this work proposes the design of an excitation current source module that can be easily implemented in existing or upcoming bioimpedance measurement systems. It is galvanically isolated to enable simultaneous multi-channel bioimpedance measurements with a very low channel-coupling. The system is based on a microcontroller in combination with a voltage-controlled current source circuit. It generates selectable sinusoidal excitation signals between 0.12 and 1.5 mA in a frequency range from 12 to 250 kHz, whereas the voltage compliance range is ±3.2 V. The coupling factor between two current sources, experimentally galvanically connected with each other, is measured to be less than −48 dB over the entire intended frequency range. Finally, suggestions for developments in the future are made.

25 CFR 170.803 - What facilities are eligible under the BIA Road Maintenance Program?

Science.gov (United States)

2010-04-01

... AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.803 What facilities are eligible under the BIA Road Maintenance Program? (a) The following public transportation facilities are eligible for maintenance under the BIA Road Maintenance Program: (1) BIA transportation facilities listed in...

Real-Time Electrical Bioimpedance Characterization of Neointimal Tissue for Stent Applications

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David Rivas-Marchena

2017-07-01

Full Text Available To follow up the restenosis in arteries stented during an angioplasty is an important current clinical problem. A new approach to monitor the growth of neointimal tissue inside the stent is proposed on the basis of electrical impedance spectroscopy (EIS sensors and the oscillation-based test (OBT circuit technique. A mathematical model was developed to analytically describe the histological composition of the neointima, employing its conductivity and permittivity data. The bioimpedance model was validated against a finite element analysis (FEA using COMSOL Multiphysics software. A satisfactory correlation between the analytical model and FEA simulation was achieved in most cases, detecting some deviations introduced by the thin “double layer” that separates the neointima and the blood. It is hereby shown how to apply conformal transformations to obtain bioimpedance electrical models for stack-layered tissues over coplanar electrodes. Particularly, this can be applied to characterize the neointima in real-time. This technique is either suitable as a main mechanism for restenosis follow-up or it can be combined with proposed intelligent stents for blood pressure measurements to auto-calibrate the sensibility loss caused by the adherence of the tissue on the micro-electro-mechanical sensors (MEMSs.

Bioelectrical impedance and visceral fat: a comparison with computed tomography in adults and elderly; Bioimpedancia eletrica e gordura visceral: uma comparacao com a tomografia computadorizada em adultos e idosos

Energy Technology Data Exchange (ETDEWEB)

Eickemberg, Michaela [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Roriz, Anna Karla Carneiro [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Fontes, Gardenia Abreu Vieira [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Sampaio, Lilian Ramos [Universidade Federal de Sao Paulo (Unifesp), Sao Paulo, SP (Brazil)

2013-05-01

Objective: To evaluate the association between electrical bioimpedance analysis (BIA) and visceral fat (VF) in adult and elderly patients. Subjects and methods: This was a cross-sectional study, with a sample of 191 subjects (52% women, 49% elderly) stratified by sex, age and body mass. Computerized tomography (VF area) and BIA (percentage of total body fat (%TBF-BIA), phase angle, reactance and resistance) data were generated. Statistical analysis was based on Pearson's Correlation Coefficient, Anova, Pearson's Chi-square, and ROC curves. Results: VF areas {>=} 130 cm{sup 2} were more prevalent among the elderly and among men. Adult females showed a stronger correlation between GV and %TBF-BIA. The other groups showed similar results and statistically significant correlations. Correlations between GV and phase angle were weak and not statistically significant. ROC Curves analyzes showed the following %TBF-BIA, which identified excess VF: for male subjects: 21.5% (adults) and 24.25% (elderly); for female subjects: 35.05% (adults) and 38.45% (elderly) with sensitivity of 78.6%, 82.1%, 83.3%, and 66.7%, and specificity of 70.6%, 62.5%, 79.1%, and 69%, respectively. Conclusion: BIA was found to have satisfactory sensitivity and specificity to predict VF; however, other devices and other techniques should be investigated to improve VF prediction. (author)

Portable bioimpedance monitor evaluation for continuous impedance measurements. Towards wearable plethysmography applications.

Science.gov (United States)

Ferreira, J; Seoane, F; Lindecrantz, K

2013-01-01

Personalised Health Systems (PHS) that could benefit the life quality of the patients as well as decreasing the health care costs for society among other factors are arisen. The purpose of this paper is to study the capabilities of the System-on-Chip Impedance Network Analyser AD5933 performing high speed single frequency continuous bioimpedance measurements. From a theoretical analysis, the minimum continuous impedance estimation time was determined, and the AD5933 with a custom 4-Electrode Analog Front-End (AFE) was used to experimentally determine the maximum continuous impedance estimation frequency as well as the system impedance estimation error when measuring a 2R1C electrical circuit model. Transthoracic Electrical Bioimpedance (TEB) measurements in a healthy subject were obtained using 3M gel electrodes in a tetrapolar lateral spot electrode configuration. The obtained TEB raw signal was filtered in MATLAB to obtain the respiration and cardiogenic signals, and from the cardiogenic signal the impedance derivative signal (dZ/dt) was also calculated. The results have shown that the maximum continuous impedance estimation rate was approximately 550 measurements per second with a magnitude estimation error below 1% on 2R1C-parallel bridge measurements. The displayed respiration and cardiac signals exhibited good performance, and they could be used to obtain valuable information in some plethysmography monitoring applications. The obtained results suggest that the AD5933-based monitor could be used for the implementation of a portable and wearable Bioimpedance plethysmograph that could be used in applications such as Impedance Cardiography. These results combined with the research done in functional garments and textile electrodes might enable the implementation of PHS applications in a relatively short time from now.

Smart Multi-Frequency Bioelectrical Impedance Spectrometer for BIA and BIVA Applications.

Science.gov (United States)

Harder, Rene; Diedrich, Andre; Whitfield, Jonathan S; Buchowski, Macie S; Pietsch, John B; Baudenbacher, Franz J

2016-08-01

Bioelectrical impedance analysis (BIA) is a noninvasive and commonly used method for the assessment of body composition including body water. We designed a small, portable and wireless multi-frequency impedance spectrometer based on the 12 bit impedance network analyzer AD5933 and a precision wide-band constant current source for tetrapolar whole body impedance measurements. The impedance spectrometer communicates via Bluetooth with mobile devices (smart phone or tablet computer) that provide user interface for patient management and data visualization. The export of patient measurement results into a clinical research database facilitates the aggregation of bioelectrical impedance analysis and biolectrical impedance vector analysis (BIVA) data across multiple subjects and/or studies. The performance of the spectrometer was evaluated using a passive tissue equivalent circuit model as well as a comparison of body composition changes assessed with bioelectrical impedance and dual-energy X-ray absorptiometry (DXA) in healthy volunteers. Our results show an absolute error of 1% for resistance and 5% for reactance measurements in the frequency range of 3 kHz to 150 kHz. A linear regression of BIA and DXA fat mass estimations showed a strong correlation (r(2)=0.985) between measures with a maximum absolute error of 6.5%. The simplicity of BIA measurements, a cost effective design and the simple visual representation of impedance data enables patients to compare and determine body composition during the time course of a specific treatment plan in a clinical or home environment.

Longitudinal Assessment of the Effect of Atrasentan on Thoracic Bioimpedance in Diabetic Nephropathy

DEFF Research Database (Denmark)

Webb, David J; Coll, Blai; Heerspink, Hiddo J L

2017-01-01

BACKGROUND: Fluid retention is a common adverse event in patients who receive endothelin (ET) receptor antagonist therapy, including the highly selective ETA receptor antagonist, atrasentan. OBJECTIVE: We performed longitudinal assessments of thoracic bioimpedance in patients with type 2 diabetes...... mellitus and nephropathy to determine whether a decrease in bioimpedance accurately reflected fluid retention during treatment with atrasentan. STUDY DESIGN: We conducted a randomized, double-blind, placebo-controlled study in 48 patients with type 2 diabetes mellitus and nephropathy who were receiving...

25 CFR 103.14 - Can BIA request additional information?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Can BIA request additional information? 103.14 Section 103.14 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES LOAN GUARANTY, INSURANCE, AND INTEREST SUBSIDY How a Lender Obtains a Loan Guaranty or Insurance Coverage § 103.14 Can BIA...

25 CFR 170.804 - How is BIA's Road Maintenance Program related to the IRR Program?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How is BIA's Road Maintenance Program related to the IRR... WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.804 How is BIA's Road Maintenance Program related to the IRR Program? The following chart illustrates how BIA's Road Maintenance Program is...

Subepidermal moisture (SEM) and bioimpedance: a literature review of a novel method for early detection of pressure-induced tissue damage (pressure ulcers).

Science.gov (United States)

Moore, Zena; Patton, Declan; Rhodes, Shannon L; O'Connor, Tom

2017-04-01

Current detection of pressure ulcers relies on visual and tactile changes at the skin surface, but physiological changes below the skin precede surface changes and have a significant impact on tissue health. Inflammatory and apoptotic/necrotic changes in the epidermal and dermal layers of the skin, such as changes in interstitial fluid (also known as subepidermal moisture (SEM)), may precede surface changes by 3-10 days. Those same epidermal and subepidermal changes result in changes in the electrical properties (bioimpedance) of the tissue, thereby presenting an objective, non-invasive method for assessing tissue damage. Clinical studies of bioimpedance for the detection of pressure ulcers have demonstrated that changes in bioimpedance correlate with increasing severity of pressure ulcer stages. Studies have also demonstrated that at anatomical locations with pressure ulcers, bioimpedance varies with distance from the centre of the pressure ulcers. The SEM Scanner, a handheld medical device, offers an objective and reliable method for the assessment of local bioimpedance, and therefore, assessment of tissue damage before signs become visible to the unaided eye. This literature review summarises pressure ulcer pathophysiology, principles of bioimpedance and clinical research using bioimpedance technology to assess pressure ulcers. © 2016 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Impact of demographic, genetic, and bioimpedance factors on gestational weight gain and birth weight in a Romanian population: A cross-sectional study in mothers and their newborns: the Monebo study (STROBE-compliant article).

Science.gov (United States)

Mărginean, Claudiu; Mărginean, Cristina Oana; Bănescu, Claudia; Meliţ, Lorena; Tripon, Florin; Iancu, Mihaela

2016-07-01

The present study had 2 objectives, first, to investigate possible relationships between increased gestational weight gain and demographic, clinical, paraclinical, genetic, and bioimpedance (BIA) characteristics of Romanian mothers, and second, to identify the influence of predictors (maternal and newborns characteristics) on our outcome birth weight (BW).We performed a cross-sectional study on 309 mothers and 309 newborns from Romania, divided into 2 groups: Group I-141 mothers with high gestational weight gain (GWG) and Group II-168 mothers with normal GWG, that is, control group.The groups were evaluated regarding demographic, anthropometric (body mass index [BMI], middle upper arm circumference, tricipital skinfold thickness, weight, height [H]), clinical, paraclinical, genetic (interleukin 6 [IL-6]: IL-6 -174G>C and IL-6 -572C>G gene polymorphisms), and BIA parameters.We noticed that fat mass (FM), muscle mass (MM), bone mass (BM), total body water (TBW), basal metabolism rate (BMR) and metabolic age (P mothers with high GWG. BW was positively correlated with mothers' FM (P G polymorphism was higher in the control group (P = 0.042).We observed that high GWG may be an important predictor factor for the afterward BW, being positively correlated with FM, TBW, BMR, metabolic age of the mothers, and negatively with the mother's smoking status. Variant genotype (GG+GC) of the IL-6 -572C>G gene polymorphism is a protector factor against obesity in mothers. All the variables considered explained 14.50% of the outcome variance.

Non-contact multi-frequency magnetic induction spectroscopy system for industrial-scale bio-impedance measurement

International Nuclear Information System (INIS)

O'Toole, M D; Marsh, L A; Davidson, J L; Tan, Y M; Armitage, D W; Peyton, A J

2015-01-01

Biological tissues have a complex impedance, or bio-impedance, profile which changes with respect to frequency. This is caused by dispersion mechanisms which govern how the electromagnetic field interacts with the tissue at the cellular and molecular level. Measuring the bio-impedance spectra of a biological sample can potentially provide insight into the sample’s properties and its cellular structure. This has obvious applications in the medical, pharmaceutical and food-based industrial domains. However, measuring the bio-impedance spectra non-destructively and in a way which is practical at an industrial scale presents substantial challenges. The low conductivity of the sample requires a highly sensitive instrument, while the demands of industrial-scale operation require a fast high-throughput sensor of rugged design. In this paper, we describe a multi-frequency magnetic induction spectroscopy (MIS) system suitable for industrial-scale, non-contact, spectroscopic bio-impedance measurement over a bandwidth of 156 kHz–2.5 MHz. The system sensitivity and performance are investigated using calibration and known reference samples. It is shown to yield rapid and consistently sensitive results with good long-term stability. The system is then used to obtain conductivity spectra of a number of biological test samples, including yeast suspensions of varying concentration and a range of agricultural produce, such as apples, pears, nectarines, kiwis, potatoes, oranges and tomatoes. (paper)

23 CFR 661.55 - How are BIA and Tribal owned IRR bridges inspected?

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false How are BIA and Tribal owned IRR bridges inspected? 661... AND TRAFFIC OPERATIONS INDIAN RESERVATION ROAD BRIDGE PROGRAM § 661.55 How are BIA and Tribal owned IRR bridges inspected? BIA and Tribally owned IRR bridges are inspected in accordance with 25 CFR part...

Estimation of Penetrated Bone Layers During Craniotomy via Bioimpedance Measurement.

Science.gov (United States)

Teichmann, Daniel; Rohe, Lucas; Niesche, Annegret; Mueller, Meiko; Radermacher, Klaus; Leonhardt, Steffen

2017-04-01

Craniotomy is the removal of a bone flap from the skull and is a first step in many neurosurgical interventions. During craniotomy, an efficient cut of the bone without injuring adjoining soft tissues is very critical. The aim of this study is to investigate the feasibility of estimating the currently penetrated cranial bone layer by means of bioimpedance measurement. A finite-element model was developed and a simulation study conducted. Simulations were performed at different positions along an elliptical cutting path and at three different operation areas. Finally, the validity of the simulation was demonstrated by an ex vivo experiment based on use of a bovine shoulder blade bone and a commercially available impedance meter. The curve of the absolute impedance and phase exhibits characteristic changes at the transition from one bone layer to the next, which can be used to determine the bone layer last penetrated by the cutting tool. The bipolar electrode configuration is superior to the monopolar measurement. A horizontal electrode arrangement at the tip of the cutting tool produces the best results. This study successfully demonstrates the feasibility to detect the transition between cranial bone layers during craniotomy by bioimpedance measurements using electrodes located on the cutting tool. Based on the results of this study, bioimpedance measurement seems to be a promising option for intra operative ad hoc information about the bone layer currently penetrated and could contribute to patient safety during neurosurgery.

Longitudinal changes and correlations of bioimpedance and anthropometric measurements in pregnancy: Simple possible bed-side tools to assess pregnancy evolution.

Science.gov (United States)

Piuri, Gabriele; Ferrazzi, Enrico; Bulfoni, Camilla; Mastricci, Luciana; Di Martino, Daniela; Speciani, Attilio Francesco

2017-12-01

The aim of this study was to assess longitudinal changes of bioimpedance analysis compared with anthropometric measurements in low-risk pregnant woman recruited in the first trimester and to observe possible differences in these indices in women who developed high-risk pregnancies. Bioimpedance indices for the three trimesters of pregnancies were calculated separately for uneventful pregnancies delivered of newborns > the 10th centile. These findings were compared with anthropometric measurements. Data of women who developed hypertensive disorders of pregnancy (HDP) or delivered SGA newborns were calculated and compared. Significantly longitudinal increases were observed in these pregnancies for total body water (TBW), free fat mass, fat mass, and extra-cellular water. These increases were paralleled body mass index (BMI), skinfolds, and waist measurements. The correlations between these two sets of findings were poor. Women who developed HDP with AGA fetuses showed significantly different bioimpedance from normal cases. TBW indices were highly significantly different since the first trimester. In pregnancies delivered of SGA newborns, these indices were opposite of the values observed in patients with HDP-AGA, TBW in these patients was significantly reduced compared with normal pregnancies. The bioelectrical impedance is a fast, simple, noninvasive way to assess the TBW content in pregnancy. Our findings are in agreement with the hypothesis that bioimpedance might help to identify early in gestation patients at risk of developing different clinical phenotypes of hypertensive disease of pregnancy and SGA fetuses.

Książka o getcie białostockim

DEFF Research Database (Denmark)

Kerszman, Gustaw

2014-01-01

Remarks about the book: Rafael Rajzner, Henry R. Lew: Losy nieopowiedziane. Zagłada Żydów białostockich 1939-1945 (Żydowski Instytut Historyczny im. E. Ringelbluma : Warszawa 2013)......Remarks about the book: Rafael Rajzner, Henry R. Lew: Losy nieopowiedziane. Zagłada Żydów białostockich 1939-1945 (Żydowski Instytut Historyczny im. E. Ringelbluma : Warszawa 2013)...

Literatura białoruska w Polsce po roku 1989. O potrzebie tworzenia bazy literackiej

Directory of Open Access Journals (Sweden)

Grażyna Charytoniuk-Michiej

2014-12-01

Full Text Available Belarusian literature in Poland after 1989. About the necessity of developing a literature database Speaking about Belarusian literature in Poland we focus on fiction, its translation into Polish and the study of literature. The existence of the Belarusian literature in Poland in the post-war period is indicated by the following bibliographies: a bibliography of translations for the period 1945–1994 (G. Charytoniuk, Literatura białoruska w Polsce. Bibliografia przekładów za lata 1945–1994, Białystok 1996 and a subject bibliography for the period 1945–1998 (G. Charytoniuk, Polskie białorutenika literackie. Bibliografia przedmiotowa 1945–1998, Białystok 1998. The new political, economical and social conditions in Poland after 1989 have had an influence on the situation of the Belarusian literature. In addition to the existing departments some new university departments and scientific branches have been organized. Their aim is to realize new scientific projects connected with the Belarusian literature in Poland and Belarus. A lot of nongovernment organizations (funds, partnerships, associations have been organized not only in Bialystok region, but also in the other parts of the country. A new publishing market has been established which has focused on the modern literature of Central and Eastern Europe including Belarusian literature. The Internet also plays an important role in popularization of the Belarusian literature. That literature has been included in the database of the National library (Przewodnik Bibliograficzny, Bibliografia Zawartości Czasopism, regional libraries (Bibliografia województwa podlaskiego and the digital library (Polska Bibliografia Literacka. The information is searched by institutional scientific depositories and digital libraries. The considerable part of the information has not been registered in the bibliographic database. In this situation it is necessary to develop an integral literature

Change in fat-free mass assessed by bioelectrical impedance, total body potassium and dual energy X-ray absorptiometry during prolonged weight loss

DEFF Research Database (Denmark)

Hendel, H W; Gotfredsen, A; Højgaard, L

1996-01-01

A total of 16 obese women (body mass index (BMI) 30-43 kg m(-2)) participated in a weight reduction study. Before and after a weight loss of 11.7 +/- 7.4 kg (mean +/- SD), body composition was assessed by dual energy X-ray absorptiometry (DXA), and total body potassium counting (TBK). These measu......A total of 16 obese women (body mass index (BMI) 30-43 kg m(-2)) participated in a weight reduction study. Before and after a weight loss of 11.7 +/- 7.4 kg (mean +/- SD), body composition was assessed by dual energy X-ray absorptiometry (DXA), and total body potassium counting (TBK......). These measurements were compared with bioimpedance analysis (BIA) by applying 11 predictive BIA equations published in the literature. Predictive equations for the present study population were developed, with the use of fat-free mass (FFM) as assessed by TBK and DXA as references in multiple regression analysis....... The results of the BIA equations varied widely; FFM was generally overestimated by BIA as compared with DXA and TBK before and after weight loss. During weight loss, the FFM did not change, as estimated by DXA (1.3 +/- 2.3 kg, p > 0.05) and TBK (0.9 +/- 2.9 kg, p > 0.05). The recorded change in impedance (R...

25 CFR 170.808 - Can BIA Road Maintenance Program funds be used to improve IRR transportation facilities?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Can BIA Road Maintenance Program funds be used to improve... THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.808 Can BIA Road Maintenance Program funds be used to improve IRR transportation facilities? No. BIA Road...

25 CFR 170.401 - What is BIA's role in transportation planning?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is BIA's role in transportation planning? 170.401... RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Transportation Planning § 170.401 What is BIA's role in transportation planning? Except as provided in § 170.402...

Electrical Bioimpedance Spectroscopy on Acute Unilateral Stroke Patients: Initial Observations regarding Differences between Sides

Directory of Open Access Journals (Sweden)

Fernando Seoane

2015-01-01

Full Text Available Purpose. Electrical Bioimpedance Cerebral Monitoring is assessment in real time of health of brain tissue through study of passive dielectric properties of brain. During the last two decades theory and technology have been developed in parallel with animal experiments aiming to confirm feasibility of using bioimpedance-based technology for prompt detection of brain damage. Here, for the first time, we show that electrical bioimpedance measurements for left and right hemispheres are significantly different in acute cases of unilateral stroke within 24 hours from onset. Methods. Electrical BIS measurements have been taken in healthy volunteers and patients suffering from acute stroke within 24 hours of onset. BIS measurements have been obtained using SFB7 bioimpedance spectrometer manufactured by Impedimed ltd. and 4-electrode method. Measurement electrodes, current, and voltage have been placed according to 10–20 EEG system obtaining mutual BIS measurements from 4 different channels situated in pairs symmetrically from the midsagittal line. Obtained BIS data has been analyzed, assessing for symmetries and differences regarding healthy control data. Results. 7 out of 10 patients for Side-2-Side comparisons and 8 out 10 for central/lateral comparison presented values outside the range defined by healthy control group. When combined only 1 of 10 patients exhibited values within the healthy range. Conclusions. If these initial observations are confirmed with more patients, we can foresee emerging of noninvasive monitoring technology for brain damage with the potential to lead to paradigm shift in treatment of brain stroke and traumatic brain damage.

Utilization of BIA-Derived Bone Mineral Estimates Exerts Minimal Impact on Body Fat Estimates via Multicompartment Models in Physically Active Adults.

Science.gov (United States)

Nickerson, Brett S; Tinsley, Grant M

2018-03-21

The purpose of this study was to compare body fat estimates and fat-free mass (FFM) characteristics produced by multicompartment models when utilizing either dual energy X-ray absorptiometry (DXA) or single-frequency bioelectrical impedance analysis (SF-BIA) for bone mineral content (BMC) in a sample of physically active adults. Body fat percentage (BF%) was estimated with 5-compartment (5C), 4-compartment (4C), 3-compartment (3C), and 2-compartment (2C) models, and DXA. The 5C-Wang with DXA for BMC (i.e., 5C-Wang DXA ) was the criterion. 5C-Wang using SF-BIA for BMC (i.e., 5C-Wang BIA ), 4C-Wang DXA (DXA for BMC), 4C-Wang BIA (BIA for BMC), and 3C-Siri all produced values similar to 5C-Wang DXA (r > 0.99; total error [TE] FFM characteristics (i.e., FFM density, water/FFM, mineral/FFM, and protein/FFM) for 5C-Wang DXA and 5C-Wang BIA were each compared with the "reference body" cadavers of Brozek et al. 5C-Wang BIA FFM density differed significantly from the "reference body" in women (1.103 ± 0.007 g/cm 3 ; p FFM and mineral/FFM were significantly lower in men and women when comparing 5C-Wang DXA and 5C-Wang BIA with the "reference body," whereas protein/FFM was significantly higher (all p ≤ 0.001). 3C-Lohman BIA and 3C-Lohman DXA produced error similar to 2C models and DXA and are therefore not recommended multicompartment models. Although more advanced multicompartment models (e.g., 4C-Wang and 5C-Wang) can utilize BIA-derived BMC with minimal impact on body fat estimates, the increased accuracy of these models over 3C-Siri is minimal. Copyright © 2018 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

Combining near-subject absolute and relative measures of longitudinal hydration in hemodialysis.

Science.gov (United States)

Chan, Cian; McIntyre, Christopher; Smith, David; Spanel, Patrik; Davies, Simon J

2009-11-01

The feasibility and additional value of combining bioimpedance analysis (BIA) with near-subject absolute measurement of total body water using deuterium dilution (TBW(D)) in determining longitudinal fluid status was investigated. Fifty-nine hemodialysis patients (17 female; age 58.4 +/- 16.1 yr; body mass index 27.0 +/- 5.4) were enrolled into a 12-mo, two-center, prospective cohort study. Deuterium concentration was measured in breath by flowing-afterglow mass spectrometry using a validated protocol ensuring full equilibration with the TBW; BIA was measured using a multifrequency, multisegmental device. Comorbidity was quantified by the Stoke score. Clinicians were blinded to body composition data. At baseline and 12 mo, there was an incremental discrepancy between TBW(BIA) and TBW(D) volumes such that greater comorbidity was associated with increasing overhydration. Forty-three patients who completed the study had no longitudinal differences in the prescribed or achieved postdialysis weights. In contrast, TBW(D) increased without a change in TBW(BIA) (mean difference -0.10 L). Changes in TBW and lean body mass differed according to baseline comorbidity; without comorbidity, BIA also identified an increase in TBW and lean body mass, whereas with increasing comorbid burden, BIA failed to demonstrate increases in tissue hydration identified by TBW(D). Combined near-patient measurements of absolute and BIA-estimated TBW are achievable in a dialysis facility by identifying changes in body composition not fully appreciated by routine assessment. BIA underestimates tissue overhydration that is associated with comorbidity, resulting in reduced sensitivity to longitudinal increases during a 12-mo period.

Developing an objective evaluation method to estimate diabetes risk in community-based settings.

Science.gov (United States)

Kenya, Sonjia; He, Qing; Fullilove, Robert; Kotler, Donald P

2011-05-01

Exercise interventions often aim to affect abdominal obesity and glucose tolerance, two significant risk factors for type 2 diabetes. Because of limited financial and clinical resources in community and university-based environments, intervention effects are often measured with interviews or questionnaires and correlated with weight loss or body fat indicated by body bioimpedence analysis (BIA). However, self-reported assessments are subject to high levels of bias and low levels of reliability. Because obesity and body fat are correlated with diabetes at different levels in various ethnic groups, data reflecting changes in weight or fat do not necessarily indicate changes in diabetes risk. To determine how exercise interventions affect diabetes risk in community and university-based settings, improved evaluation methods are warranted. We compared a noninvasive, objective measurement technique--regional BIA--with whole-body BIA for its ability to assess abdominal obesity and predict glucose tolerance in 39 women. To determine regional BIA's utility in predicting glucose, we tested the association between the regional BIA method and blood glucose levels. Regional BIA estimates of abdominal fat area were significantly correlated (r = 0.554, P < 0.003) with fasting glucose. When waist circumference and family history of diabetes were added to abdominal fat in multiple regression models, the association with glucose increased further (r = 0.701, P < 0.001). Regional BIA estimates of abdominal fat may predict fasting glucose better than whole-body BIA as well as provide an objective assessment of changes in diabetes risk achieved through physical activity interventions in community settings.

Bioimpedance to screen for abdominal fat in patients with breast cancer treatment-related lymphedema.

Science.gov (United States)

de Fátima Guerreiro Godoy, Maria; Silva, Edivandra Buzato; de Godoy, Jose Maria Pereira

2016-07-28

One of the dreaded complications after the treatment of breast cancer is lymphedema. Therapies used in the treatment of breast cancer such as surgery, radiotherapy, hormone therapy and chemotherapy may be adversely affected by obesity. The objective of this study was to use bioimpedance to assess abdominal fat in women with breast cancer treatment-related lymphedema and suggest this as a screening method. Forty-five female patients with clinical diagnosis of breast cancer treatment-related lymphedema were evaluated in this quantitative cross-sectional study. A control group, composed of 38 patients with varicose veins and women attending a social support group, was matched for age and body mass index (BMI). All participants were submitted to a bioimpedance evaluation (In Body S 10), with particular attention being paid to abdominal fat and their BMI. The unpaired t -test, Fisher Exact test and Mann-Whitney test were used for statistical analysis and an alpha error of 5%. There was no significant difference (p -value = 0.23) in the mean BMI between the study group (27.79 kg∕m2) and the control group (28.80 kg∕m2). The mean abdominal circumference, a measure of abdominal fat, of the women in the study group was 130.54 cm2 and for the control group it was 102.24 cm2 (p -value = 0.0037). Thus the study group had more abdominal fat (p -value = 0.0003). Moreover, on comparing obese patients in the two groups, the study group had more abdominal fat (p -value = 0.02). However, no significant difference was observed comparing non-obese patients (p -value = 0.6). The comparison of obese patients with non-obese patients in the control group identifies an association between obesity and abdominal fat (p -value abdominal fat than the general population with bioimpedance.

25 CFR 170.2 - What is the IRR Program and BIA Road Maintenance Program policy?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is the IRR Program and BIA Road Maintenance Program... and BIA Road Maintenance Program policy? (a) It is the policy of the Secretary of the Interior and the... designed to enable Indian tribes to participate in all contractible IRR and BIA Road Maintenance programs...

25 CFR 171.305 - Will BIA provide leaching service to me?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Will BIA provide leaching service to me? 171.305 Section... OPERATION AND MAINTENANCE Water Use § 171.305 Will BIA provide leaching service to me? (a) We may provide you leaching service if: (1) You submit a written plan that documents how soil salinity limits your...

22 Cases of BIA-ALCL: Awareness and Outcome Tracking from the Italian Ministry of Health.

Science.gov (United States)

Antonella, Campanale; Rosaria, Boldrini; Marcella, Marletta

2017-09-13

To date, 359 cases of anaplastic large cell lymphoma in women with breast implants (BIA-ALCL) worldwide have been reported out of more than 10 million implanted patients but Health Care Authorities suspect this is a possible underestimation and the limited number of cases makes it difficult to clarify its etiology. The General Directorate of Medical Devices and Pharmaceutical Services of the Italian Ministry of Health (IMoH) has examined and studied the Italian BIA-ALCL cases, and the aim of this study is to report on the knowledge and experience gained on this new emerging disease. An official document has been diffused by the IMoH to all the Italian medical associations, aiming at encouraging all physicians to notify each BIA-ALCL case through the compilation of a specific on-line form. A retrospective study has been performed on the notified BIA-ALCL cases collected in the IMoH's database named DISPOVIGILANCE. Research on DISPOVIGILANCE gives back a list of 22 Italian BIA-ALCL cases. The patients' mean age was 49.6 years (range 30 -71). The average time to the onset of the symptoms was 6.8 years (range 1-22). The average time to the diagnosis was 7.8 years (range 4 -22). The estimated incidence of the Italian BIA-ALCL cases related to 2015 is 2.8 per 100.000 patients. The BIA-ALCL pathogenesis remains unknown. The Italian Ministry of Health, together with scientific associations and other Competent Authorities worldwide, is working on the BIA-ALCL issue to increase awareness and knowledge of this disease by healthcare professionals.

76 FR 4369 - Interim Deputation Agreements; Interim BIA Adult Detention Facility Guidelines

Science.gov (United States)

2011-01-25

... Deputation Agreements are effective on January 25, 2011. FOR FURTHER INFORMATION CONTACT: Charles Addington... http://www.bia.gov/WhoWeAre/BIA/OJS/index.htm . The documents were the subject of tribal consultation in November and December 2010. The Office of Justice Services continues consultation on the Tribal...

Bioimpedance and Fluid Status in Children and Adolescents Treated With Dialysis

NARCIS (Netherlands)

Milani, Gregorio P.; Groothoff, Jaap W.; Vianello, Federica A.; Fossali, Emilio F.; Paglialonga, Fabio; Edefonti, Alberto; Agostoni, Carlo; Consonni, Dario; van Harskamp, Dewi; van Goudoever, Johannes B.; Schierbeek, Henk; Oosterveld, Michiel J. S.

2017-01-01

Assessment of hydration status in patients with chronic kidney failure treated by dialysis is crucial for clinical management decisions. Dilution techniques are considered the gold standard for measurement of body fluid volumes, but they are unfit for day-to-day care. Multifrequency bioimpedance has

Influence of acute consumption of caffeine vs. placebo over Bia-derived measurements of body composition: a randomized, double-blind, crossover design.

Science.gov (United States)

Williamson, Cassie M; Nickerson, Brett S; Bechke, Emily E; McLester, Cherilyn N; Kliszczewicz, Brian M

2018-01-01

Bioelectrical impedance analysis (BIA) is often used to estimate total body water (TBW), intracellular body water (ICW), extracellular body water (ECW), and body fat percentage (BF%). A common restriction for BIA analysis is abstinence from caffeine 12-h prior to testing. However, research has yet to determine whether the consumption of caffeine influences BIA testing results. The purpose of this study was to determine if the consumption of caffeine influences BIA-derived BF% and body water values in habitual caffeine users. Twenty apparently healthy males (26.6 ± 4.1 years) identified as habitual caffeine consumers (≥ one 95 mg serving per day ≥ four days per week) participated in this study. Participants came to the lab on three occasions, the first visit serving as the control (CON) with no supplementation. The remaining two visits were performed in a randomized double-blind, cross-over fashion. Participants consumed 200 mg of dextrose (PLA) or caffeine (CAF) in capsule form. During each visit, seven multi-frequency BIA measurements were conducted before (PRE) and after (15-min, 30-min, 45-min, 60-min, 75-min, 90-min) consumption. Repeated measures ANOVA revealed BF% for CAF was lower than the CON and PLA conditions at PRE and 15-min ( p  Caffeine consumption in habitual users produced trivial changes in TBW, ECW, ICW, or BF%. Therefore, the pre-testing guidelines for caffeine consumption may not be necessary in habitual caffeine consumers.

A randomized controlled trial of long term effect of BCM guided fluid management in MHD patients (BOCOMO study: rationales and study design

Directory of Open Access Journals (Sweden)

Liu Li

2012-09-01

Full Text Available Abstract Background Bioimpedance analysis (BIA has been reported as helpful in identifying hypervolemia. Observation data showed that hypervolemic maintenance hemodialysis (MHD patients identified using BIA methods have higher mortality risk. However, it is not known if BIA-guided fluid management can improve MHD patients’ survival. The objectives of the BOCOMO study are to evaluate the outcome of BIA guided fluid management compared with standard care. Methods This is a multicenter, prospective, randomized, controlled trial. More than 1300 participants from 16 clinical sites will be included in the study. The enrolment period will last 6 months, and minimum length of follow-up will be 36 months. MHD patients aged between 18 years and 80 years who have been on MHD for at least 3 months and meet eligibility criteria will be invited to participate in the study. Participants will be randomized to BIA arm or control arm in a 1:1 ratio. A portable whole body bioimpedance spectroscopy device (BCM—Fresenius Medical Care D GmbH will be used for BIA measurement at baseline for both arms of the study. In the BIA arm, additional BCM measurements will be performed every 2 months. The primary intent-to-treat analysis will compare outcomes for a composite endpoint of death, acute myocardial infarction, stroke or incident peripheral arterial occlusive disease between groups. Secondary endpoints will include left ventricular wall thickness, blood pressure, medications, and incidence and length of hospitalization. Discussions Previous results regarding the benefit of strict fluid control are conflicting due to small sample sizes and unstable dry weight estimating methods. To our knowledge this is the first large-scale, multicentre, prospective, randomized controlled trial to assess whether BIS-guided volume management improves outcomes of MHD patients. The endpoints of the BOCOMO study are of utmost importance to health care providers. In order to obtain

Evaluation of fluid status related parameters in hemodialysis and peritoneal dialysis patients: Clinical usefulness of bioimpedance analysis

Directory of Open Access Journals (Sweden)

Zülfükar Yılmaz

2014-01-01

Conclusions: Fluid overload may be an even more prevalent and serious problem in PD patients. Overhydration is closely associated with increased blood pressure and LVMI. OH/ECW ratio, a derived parameter of fluid load measured by BIA, was a significant and independent determinant of SBP and LVMI.

25 CFR 166.901 - How will the BIA select an agriculture intern?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How will the BIA select an agriculture intern? 166.901... PERMITS Agriculture Education, Education Assistance, Recruitment, and Training § 166.901 How will the BIA select an agriculture intern? (a) The purpose of the agriculture intern program is to ensure the future...

Bioimpedance monitoring of 3D cell culturing-Complementary electrode configurations for enhanced spatial sensitivity

DEFF Research Database (Denmark)

Canali, Chiara; Heiskanen, Arto; Muhammad, Haseena Bashir

2015-01-01

A bioimpedance platform is presented as a promising tool for non-invasive real-time monitoring of the entire process of three-dimensional (3D) cell culturing in a hydrogel scaffold. In this study, the dynamics involved in the whole process of 3D cell culturing, starting from polymerisation...... spectroscopic (EIS) characterisation were used to determine the configurations' sensitivity field localisation. The 2T setup gives insight into the interfacial phenomena at both electrode surfaces and covers the central part of the 3D cell culture volume, while the four 3T modes provide focus on the dynamics...... the tested biomimetic environment, paving the way to further developments in bioimpedance tracking of 3D cell cultures and tissue engineering....

A Batteryless Sensor ASIC for Implantable Bio-Impedance Applications.

Science.gov (United States)

Rodriguez, Saul; Ollmar, Stig; Waqar, Muhammad; Rusu, Ana

2016-06-01

The measurement of the biological tissue's electrical impedance is an active research field that has attracted a lot of attention during the last decades. Bio-impedances are closely related to a large variety of physiological conditions; therefore, they are useful for diagnosis and monitoring in many medical applications. Measuring living tissues, however, is a challenging task that poses countless technical and practical problems, in particular if the tissues need to be measured under the skin. This paper presents a bio-impedance sensor ASIC targeting a battery-free, miniature size, implantable device, which performs accurate 4-point complex impedance extraction in the frequency range from 2 kHz to 2 MHz. The ASIC is fabricated in 150 nm CMOS, has a size of 1.22 mm × 1.22 mm and consumes 165 μA from a 1.8 V power supply. The ASIC is embedded in a prototype which communicates with, and is powered by an external reader device through inductive coupling. The prototype is validated by measuring the impedances of different combinations of discrete components, measuring the electrochemical impedance of physiological solution, and performing ex vivo measurements on animal organs. The proposed ASIC is able to extract complex impedances with around 1 Ω resolution; therefore enabling accurate wireless tissue measurements.

PREFACE: First Latin-American Conference on Bioimpedance (CLABIO 2012)

Science.gov (United States)

Bertemes Filho, Pedro

2012-12-01

The past decade has witnessed an unprecedented growth in medical technologies and a new generation of diagnostics, characterized by mobility, virtualization, homecare and costs. The ever growing demand and the rapid need for low cost tools for characterizing human tissue, and supporting intelligence and technologies for non-invasive tissue cancer investigation raise unique and evolving opportunities for research in Electrical Bioimpedance. The CLABIO2012 - First Latin American Conference on Bioimpedance is a premier Latin-American conference on Bioimpedance for research groups working on Electrical Bioimpedance. It allows Latin American researchers to share their experiences with other groups from all over the world by presenting scientific work and potential innovations in this research area and also in the social events promoting informal get togethers in the Brazilian style. The work covers a broad range including Biomedical Engineering and Computing, Medical Physics and Medical Sciences, Environment, Biology and Chemistry. Also, the Conference is intended to give students and research groups the opportunity to learn more about Bioimpedance as an important tool in biological material characterization and also in diagnosis. The conference is designed to showcase cutting edge research and accomplishments, and to enrich the educational and industrial experience in this field. It also represents a unique opportunity to meet colleagues and friends, exchanging ideas, and learning about new developments and best practice, while working to advance the understanding of the knowledge base that we will collectively draw upon in the years ahead to meet future challenges. Participants will attend presentations by scholars representing both institutes and academia. The CLABIO2012 proceedings include over 25 papers selected via a peer review process. The conference program features tutorial talks by world-leading scholars and five sessions for regular paper oral presentations

25 CFR 170.614 - Can a tribe receive funds before BIA publishes the notice of funding availability?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Can a tribe receive funds before BIA publishes the notice... Contracts and Agreements Under Isdeaa § 170.614 Can a tribe receive funds before BIA publishes the notice of funding availability? A tribe can receive funds before BIA publishes the notice of funding availability...

Design of Bioimpedance Monitor and Its Application to Atrioventricular Delay Optimization

Czech Academy of Sciences Publication Activity Database

Vondra, Vlastimil; Viščor, Ivo; Halámek, Josef; Jurák, Pavel

2009-01-01

Roč. 36, - (2009), s. 481-484 ISSN 0276-6574 R&D Projects: GA AV ČR IAA200650801; GA ČR GA102/08/1129 Institutional research plan: CEZ:AV0Z20650511 Keywords : bioimpedance monitor * impedance cardiography Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering http://cinc.mit.edu/archives/2009/pdf/0481.pdf

Bioimpedance monitoring of cellular hydration during hemodialysis therapy.

Science.gov (United States)

Montgomery, Leslie D; Montgomery, Richard W; Gerth, Wayne A; Lew, Susie Q; Klein, Michael D; Stewart, Julian M; Medow, Marvin S; Velasquez, Manuel T

2017-10-01

Introduction The aim of this paper is to describe and demonstrate how a new bioimpedance analytical procedure can be used to monitor cellular hydration of End Stage Renal Disease (ESRD) patients during hemodialysis (HD). Methods A tetra-polar bioimpedance spectroscope (BIS), (UFI Inc., Morro Bay, CA), was used to measure the tissue resistance and reactance of the calf of 17 ESRD patients at 40 discrete frequencies once a minute during dialysis treatment. These measurements were then used to derive intracellular, interstitial, and intravascular compartment volume changes during dialysis. Findings The mean (± SD) extracellular resistance increased during dialysis from 92.4 ± 3.5 to 117.7 ± 5.8 Ohms. While the mean intracellular resistance decreased from 413.5 ± 11.7 to 348.5 ± 8.2 Ohms. It was calculated from these data that the mean intravascular volume fell 9.5%; interstitial volume fell 33.4%; and intracellular volume gained 20.3%. Discussion These results suggest that an extensive fluid shift into the cells may take place during HD. The present research may contribute to a better understanding of how factors that influence fluid redistribution may affect an ESRD patient during dialysis. In light of this finding, it is concluded that the rate of vascular refill is jointly determined with the rate of "cellular refill" and the transfer of fluid from the intertitial compartment into the intravascular space. © 2016 International Society for Hemodialysis.

Method and device for bio-impedance measurement with hard-tissue applications

International Nuclear Information System (INIS)

Guimerà, A; Calderón, E; Los, P; Christie, A M

2008-01-01

Bio-impedance measurements can be used to detect and monitor several properties of living hard-tissues, some of which include bone mineral density, bone fracture healing or dental caries detection. In this paper a simple method and hardware architecture for hard tissue bio-impedance measurement is proposed. The key design aspects of such architecture are discussed and a commercial handheld ac impedance device is presented that is fully certified to international medical standards. It includes a 4-channel multiplexer and is capable of measuring impedances from 10 kΩ to 10 MΩ across a frequency range of 100 Hz to 100 kHz with a maximum error of 5%. The device incorporates several user interface methods and a Bluetooth link for bi-directional wireless data transfer. Low-power design techniques have been implemented, ensuring the device exceeds 8 h of continuous use. Finally, bench test results using dummy cells consisting of parallel connected resistors and capacitors, from 10 kΩ to 10 MΩ and from 20 pF to 100 pF, are discussed

Method and device for bio-impedance measurement with hard-tissue applications.

Science.gov (United States)

Guimerà, A; Calderón, E; Los, P; Christie, A M

2008-06-01

Bio-impedance measurements can be used to detect and monitor several properties of living hard-tissues, some of which include bone mineral density, bone fracture healing or dental caries detection. In this paper a simple method and hardware architecture for hard tissue bio-impedance measurement is proposed. The key design aspects of such architecture are discussed and a commercial handheld ac impedance device is presented that is fully certified to international medical standards. It includes a 4-channel multiplexer and is capable of measuring impedances from 10 kOmega to 10 MOmega across a frequency range of 100 Hz to 100 kHz with a maximum error of 5%. The device incorporates several user interface methods and a Bluetooth link for bi-directional wireless data transfer. Low-power design techniques have been implemented, ensuring the device exceeds 8 h of continuous use. Finally, bench test results using dummy cells consisting of parallel connected resistors and capacitors, from 10 kOmega to 10 MOmega and from 20 pF to 100 pF, are discussed.

Fast BIA-amperometric determination of isoniazid in tablets.

Science.gov (United States)

Quintino, Maria S M; Angnes, Lúcio

2006-09-26

This paper proposes a new, fast and precise method to analyze isoniazid based on the electrochemical oxidation of the analyte at a glassy carbon electrode in 0.1M NaOH. The quantification was performed utilizing amperometry associated with batch injection analysis (BIA) technique. Fast sequential analysis (60 determinations h(-1)) in an unusually wide linear dynamic range (from 2.5 x 10(-8) to 1.0 x 10(-3)M), with high sensitivity and low limits of detection (4.1 x 10(-9)M) and quantification (1.4 x 10(-8)M), was achieved. Such characteristics allied to a good repeatability of the current responses (relative standard deviation of 0.79% for 30 measurements), were explored for the specific determination of isoniazid in isoniazid-rifampin tablet.

A multichannel bioimpedance monitor for full-body blood flow monitoring

Czech Academy of Sciences Publication Activity Database

Vondra, Vlastimil; Jurák, Pavel; Viščor, Ivo; Halámek, Josef; Leinveber, P.; Matějková, M.; Soukup, L.

2016-01-01

Roč. 61, č. 1 (2016), s. 107-118 ISSN 0013-5585 R&D Projects: GA MŠk(CZ) LO1212; GA MŠk ED0017/01/01; GA ČR GAP102/12/2034 Institutional support: RVO:68081731 Keywords : bioimpedance * blood flow * cardiac output * multichannel measurement * non- invasive measurements * pulse wave velocity Subject RIV: FS - Medical Facilities ; Equipment Impact factor: 0.915, year: 2016

Which echocardiographic parameter is a better marker of volume status in hemodialysis patients?

Science.gov (United States)

Sabaghian, Tahereh; Hajibaratali, Bahareh; Samavat, Shiva

2016-11-01

Bio-impedance analysis (BIA) is a preferred method for estimating the volume status. However, it cannot be utilized in daily practice. Since the assessment of the volume status is important and challenging for hemodialysis (HD) patients, the aim of study was to determine the volume status in chronic HD patients using echocardiographic parameters and assess its correlation with BIA. In this cross-sectional analysis, echocardiography and BIA were performed on 30 chronic HD patients 30 min before and 30 min after dialysis. All the cases of dialysis were performed in the middle of the week. This study also assessed the correlation between echocardiographic parameters and BIA parameters. There were significant differences between ECW, TBW, and TBW% (TBW/W) before and after HD. Significant differences were observed between echocardiographic parameters of IVCD, IVCDi min , IVCDi max before and after the HD. LVEDD, LVESD, LA area, mitral valve inflow, E/E', and IVRT, were improved after dialysis, too. There was a significant correlation between IVCDi min as an index of volume status, ECW% and TBW% before HD and IVCDi min change after dialysis had a significant correlation with %ECW change after dialysis. Comparison between hypertensive and non-hypertensive groups indicated IVCDi min was significantly lower in non-hypertensive group after dialysis. Our results showed a correlation between IVCDi min and BIA parameters before HD. So, it seems that IVCDi min can be a good parameter for determining the volume status of HD patients. However, further studies, with larger sample size and with a prospective study design, are required to confirm these results.

23 CFR 661.35 - What percentage of IRRBP funding is available for use on BIA and Tribally owned IRR bridges, and...

Science.gov (United States)

2010-04-01

... BIA and Tribally owned IRR bridges, and non-BIA owned IRR bridges? 661.35 Section 661.35 Highways... RESERVATION ROAD BRIDGE PROGRAM § 661.35 What percentage of IRRBP funding is available for use on BIA and Tribally owned IRR bridges, and non-BIA owned IRR bridges? (a) Up to 80 percent of the available funding...

Multi-frequency bioelectrical impedance analysis (BIA) compared to magnetic resonance imaging (MRI) for estimation of fat-free mass in colorectal cancer patients treated with chemotherapy

DEFF Research Database (Denmark)

Palle, Stine Skov; Tang Møllehave, Line; Kadkhoda, Zahra Taheri

2016-01-01

during the course of their treatments. Objective: To examine relationships between single cross-sectional thighs magnetic resonance imaging (MRI), skeletal muscle mass (SM) as reference and multi-frequency bioelectrical impedance analysis (BIA) fat free mass (FFM) in patients with colorectal cancer...... undergoing chemotherapy. Design: In an observational, prospective study we examine the relationships between single cross-sectional thighs MRI (T1-weighted (1.5 T) SM compared to FFM BIA (8-electrodes multi-frequency Tanita MC780MA)) and FFM skin-fold thickness (ST) (4-points (Harpenden, Skinfold Caliper......)) and SM equation for non-obese persons from Lee et al. 2000 (L2000) (based on age, height, weight, sex and race). FFM and SM (kg) were calculated based on either area (MRI) or weight. Results: 18 CRC patients (10 males and 8 females) with mean (SD) age 67 yr (6) were measured at baseline, and 13 were...

Perfusion-based three dimensional (3D) tissue engineering platform with integrated bioimpedance sensing

DEFF Research Database (Denmark)

Muhammad, Haseena Bashir; Canali, Chiara; Heiskanen, Arto

2014-01-01

We present an 8-channel bioreactor array with integrated bioimpedance sensors, which enables perfusion culture of cells seeded onto porous 3D scaffolds. Results show the capability of the system for monitoring cell proliferation within the scaffolds through a culture period of 19 days....

Bioimpedance-Guided Fluid Management in Hemodialysis Patients

Science.gov (United States)

Arias-Guillén, Marta; Wabel, Peter; Fontseré, Néstor; Carrera, Montserrat; Campistol, José Maria; Maduell, Francisco

2013-01-01

Summary Background and objectives Achieving and maintaining optimal fluid status remains a major challenge in hemodialysis therapy. The aim of this interventional study was to assess the feasibility and clinical consequences of active fluid management guided by bioimpedance spectroscopy in chronic hemodialysis patients. Design, setting, participants, & measurements Fluid status was optimized prospectively in 55 chronic hemodialysis patients over 3 months (November 2011 to February 2012). Predialysis fluid overload was measured weekly using the Fresenius Body Composition Monitor. Time-averaged fluid overload was calculated as the average between pre- and postdialysis fluid overload. The study aimed to bring the time-averaged fluid overload of all patients into a target range of 0.5±0.75 L within the first month and maintain optimal fluid status until study end. Postweight was adjusted weekly according to a predefined protocol. Results Time-averaged fluid overload in the complete study cohort was 0.9±1.6 L at baseline and 0.6±1.1 L at study end. Time-averaged fluid overload decreased by −1.20±1.32 L (P<0.01) in the fluid-overloaded group (n=17), remained unchanged in the normovolemic group (n=26, P=0.59), and increased by 0.59±0.76 L (P=0.02) in the dehydrated group (n=12). Every 1 L change in fluid overload was accompanied by a 9.9 mmHg/L change in predialysis systolic BP (r=0.55, P<0.001). At study end, 76% of all patients were either on time-averaged fluid overload target or at least closer to target than at study start. The number of intradialytic symptoms did not change significantly in any of the subgroups. Conclusions Active fluid management guided by bioimpedance spectroscopy was associated with an improvement in overall fluid status and BP. PMID:23949235

25 CFR 171.310 - Can I use water delivered by BIA for livestock purposes?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Can I use water delivered by BIA for livestock purposes? 171.310 Section 171.310 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER IRRIGATION OPERATION AND MAINTENANCE Water Use § 171.310 Can I use water delivered by BIA for livestock...

BIOIMPEDANCE VECTOR ANALYSIS AS A TOOL FOR DETERMINATION AND ADJUSTMENT OF DRY WEIGHT IN HEMODIALYSIS PATIENTS

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Ximena Atilano

2012-06-01

Full Text Available The hemodialysis (HD patient is fluid overloaded, even when there is no apparent edema. Due to this, is vital to know the dry weight. No clinical or laboratory parameters are reliable, simple and accessible for this purpose. The bioelectrical impedance has been applied to estimate body fluids and dry weight. The purpose was to use the bioelectrical vector analysis (BIVA as a tool to adjust the intensity of ultrafiltration and achievement of dry weight in HD patients. We performed monthly measurements of bioimpedance in 24 HD patients pre-and post-dialysis for four months. We plotted the patient´s vectors in the RXc graph in order to meet individually hydration status and adjust the dry weight. Nutritional status was evaluated by Bilbrey Index. Adjustment on dry weight, was made in 18 patients, 13 of whom (72% were able to reach it. The postdialysis vectors, migrated to upper quadrants, indicating adequate hydration. Postdialysis vectors at the end of the study were significantly different compared to baseline (Figure 1. Five patients didn´t reach dry weight despite the adjustments, 4 were men with overhydration and 3 of them were severely malnourished. A woman remained dehydrated. In conclusion, the impedance vector analysis is a useful tool for adjusting dry weight in hemodialysis patients.fx1

Percent body fat and BMI in indigenous and mestizo children from South, Centre and North Mexico derived from bioimpedance analysis (BIA) and deuterium oxide dilution

International Nuclear Information System (INIS)

Valencia, Mauro E; Ramirez-Lopez, Erik; Ramos-Salas, Je; Bourges, Hector; Espinoza, Teresa

2014-01-01

Full text: Background. Body mass index (BMI) is an international standard to evaluate nutritional status but has the inability to distinguish fat mass from fat free mass, especially with regards to ethnicity. Mexico is the eight country in ethnic diversity in the world. The changes in fat mass and fat free mass offers the possibility to evaluate the effects of intervention programs in shorter periods. Objective. The purpose of the present study was to investigate the relationship between body composition and anthropometric characteristics of indigenous and mestizo Mexican children. Subject and Methods. A total of 1618 male and female indigenous (n = 498) and mestizo (n = 1120) children 7-9 years, were selected by stratified multiple stage cluster sampling. Indigenous groups and States were: Tarahumaras (Chihuahua), Mayos (Sonora), Nahuas (Puebla), Otomíes (Hidalgo), Tzotziles (Chiapas) and Mayas (Yucatan Peninsula). Mestizos form the same regions were included. Fat free mass and fat mass were obtained from a previously reported BIA cross validated equation using deuterium oxide dilution from 339 children from the same population, groups and regions. Results. The indigenous groups had 18.5 + 5.9 % fat compared to 23.5 + 8.4 in the mestizos (p<0.0001). Nahuas had the lowest % fat (p<0.0001) with 16.5 + 5.7, compared to Mayos, Tarahumaras and Mayas that had 18.6 + 6.2, 19.0 + 6.3 and 18.0 + 6.5 respectively. Mestizos form the Centre, North, and South had the highest levels of % body fat (p<0.001) with 25.4 + 7.7, 21.9 + 8.2, and 20.5 + 7.8, respectively. In indigenous children (n = 498) the 5th percentile (95% CI) corresponded to 9 (8,10) % body fat, while for Mestizos (n = 1120), the 5th percentile was 10 (9,11). Using this percentile, only one third of the children approximately of both groups would be classified as thin by WHO and IOTF classifications. Conclusion. Indigenous children had lower body fat than mestizos, however, the relationship of BMI to % body fat

Od internacjonalnej do własnej historii – mniejszość białoruska w Polsce

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Wojciech Śleszyński

2017-12-01

Full Text Available From international history to one’s own history – Belorusian minority in Poland After World War II the Belarusians who did not leave Poland could gain upward mobility only if they avoided displaying their national and cultural distinctiveness. Belarusians made a political choice which coincided with a vision of history and thus accepted a historical narrative spread by communist circles. The narrative constructed by the Belarusian minority was consistent with the officially proclaimed state ideological narrative. It contained mostly the history of the Communist Party of Western Belarus and described a difficult situation of Belarus in the Second Polish Republic and during World War II (especially the Great Patriotic War. The Belarusian community made first attempts to rebuild the current vision of the world in 1980–1981. Students tried to create an alternative historical narrative that contradicted the communist one. However, it was a gradual collapse of the communist system that became an impetus for more active development of the Belarusian minority in Poland, and consequently, the creation of its own national vision of history. The Belarusian heritage has been based on the Belarusian People's Republic and the Grand Duchy of Lithuania, and not, as it was in the Soviet Socialist Republic of Belarus or after 1994, on the Republic of Belarus and the victory in the Great Patriotic War.   Od internacjonalnej do własnej historii – mniejszość białoruska w Polsce Pozostała w Polsce po II wojnie światowej społeczność białoruska uzyskała możliwość awansu społecznego pod warunkiem nieeksponowania swojej narodowej i kulturowej odrębności. Białorusini, dokonując wyboru politycznego, pokrywającego się z wyborem wizji historii, akceptowali obraz dziejów prezentowany przez środowiska komunistyczne. Konstruowany przez mniejszość białoruską przekaz historyczny zgodny był z oficjalnie głoszonym państwowym przekazem

Detection of questionable occlusal carious lesions using an electrical bioimpedance method with fractional electrical model

Energy Technology Data Exchange (ETDEWEB)

Morais, A. P. [Biomedical Engineering Program, COPPE, Rio de Janeiro (Brazil); Salgado de Oliveira University, Marechal Deodoro Street, 217 – Centro, Niterói, Rio de Janeiro (Brazil); Pino, A. V. [Biomedical Engineering Program, COPPE, Rio de Janeiro (Brazil); Souza, M. N. [Biomedical Engineering Program, COPPE, Rio de Janeiro (Brazil); Electronics Department at Polytechnic School, Federal University of Rio de Janeiro, Centro de Tecnologia Bloco H sala 217, Ilha do Fundão, Rio de Janeiro (Brazil)

2016-08-15

This in vitro study evaluated the diagnostic performance of an alternative electric bioimpedance spectroscopy technique (BIS-STEP) detect questionable occlusal carious lesions. Six specialists carried out the visual (V), radiography (R), and combined (VR) exams of 57 sound or non-cavitated occlusal carious lesion teeth classifying the occlusal surfaces in sound surface (H), enamel caries (EC), and dentinal caries (DC). Measurements were based on the current response to a step voltage excitation (BIS-STEP). A fractional electrical model was used to predict the current response in the time domain and to estimate the model parameters: Rs and Rp (resistive parameters), and C and α (fractional parameters). Histological analysis showed caries prevalence of 33.3% being 15.8% hidden caries. Combined examination obtained the best traditional diagnostic results with specificity = 59.0%, sensitivity = 70.9%, and accuracy = 60.8%. There were statistically significant differences in bioimpedance parameters between the H and EC groups (p = 0.016) and between the H and DC groups (Rs, p = 0.006; Rp, p = 0.022, and α, p = 0.041). Using a suitable threshold for the Rs, we obtained specificity = 60.7%, sensitivity = 77.9%, accuracy = 73.2%, and 100% of detection for deep lesions. It can be concluded that BIS-STEP method could be an important tool to improve the detection and management of occlusal non-cavitated primary caries and pigmented sites.

Detection of questionable occlusal carious lesions using an electrical bioimpedance method with fractional electrical model

International Nuclear Information System (INIS)

Morais, A. P.; Pino, A. V.; Souza, M. N.

2016-01-01

This in vitro study evaluated the diagnostic performance of an alternative electric bioimpedance spectroscopy technique (BIS-STEP) detect questionable occlusal carious lesions. Six specialists carried out the visual (V), radiography (R), and combined (VR) exams of 57 sound or non-cavitated occlusal carious lesion teeth classifying the occlusal surfaces in sound surface (H), enamel caries (EC), and dentinal caries (DC). Measurements were based on the current response to a step voltage excitation (BIS-STEP). A fractional electrical model was used to predict the current response in the time domain and to estimate the model parameters: Rs and Rp (resistive parameters), and C and α (fractional parameters). Histological analysis showed caries prevalence of 33.3% being 15.8% hidden caries. Combined examination obtained the best traditional diagnostic results with specificity = 59.0%, sensitivity = 70.9%, and accuracy = 60.8%. There were statistically significant differences in bioimpedance parameters between the H and EC groups (p = 0.016) and between the H and DC groups (Rs, p = 0.006; Rp, p = 0.022, and α, p = 0.041). Using a suitable threshold for the Rs, we obtained specificity = 60.7%, sensitivity = 77.9%, accuracy = 73.2%, and 100% of detection for deep lesions. It can be concluded that BIS-STEP method could be an important tool to improve the detection and management of occlusal non-cavitated primary caries and pigmented sites.

43 CFR 30.128 - What happens if an error in BIA's estate inventory is alleged?

Science.gov (United States)

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What happens if an error in BIA's estate... INDIAN PROBATE HEARINGS PROCEDURES Judicial Authority and Duties § 30.128 What happens if an error in BIA's estate inventory is alleged? This section applies when, during a probate proceeding, an interested...

25 CFR 115.422 - As a custodial parent, the legal guardian, the person who BIA has recognized as having control...

Science.gov (United States)

2010-04-01

... BIA has recognized as having control and custody of the minor, or an emancipated minor, what are your... BIA has recognized as having control and custody of the minor, or an emancipated minor, what are your... legal guardian, the person who BIA has recognized as having control and custody of the minor, or an...

Addition of internal electrodes is beneficial for focused bioimpedance measurements in the lung.

Science.gov (United States)

Orschulik, Jakob; Hochhausen, Nadine; Czaplik, Michael; Teichmann, Daniel; Leonhardt, Steffen; Walter, Marian

2018-03-29

Bioimpedance measurements such as bioimpedance spectroscopy (BIS) or electrical impedance tomography (EIT) are used in many biomedical applications. While BIS measures and analyzes the impedance in a frequency range at constant electrode positions, EIT aims to reconstruct images of the conductivity distribution from multiple measurements at different electrode positions. Our aim is to add spatial information to tetrapolar BIS measurements by using electrode positions that focus measurements on desired regions of interest. In this paper, we aim to investigate, whether internal electrodes that can be integrated into breathing or gastroesophageal tubes, can improve the local sensitivity of bioimpedance spectroscopy measurements. We present the results of a simulation study, in which we investigated more than 4 M different electrode configurations on their ability to monitor specific regions of interest (ROI) in the lung. Based on the sensitivity, which describes the impact of a conductivity change on the measured impedance, we define three main criteria which we use to evaluate our simulation results: the selectivity [Formula: see text], which describes the impact of a conductivity change inside the region of interest compared to a conductivity change outside the ROI; the homogeneity [Formula: see text], which describes the distribution of the sensitivity inside the ROI; and the absolute impedance contribution ratio [Formula: see text], which describes the contribution of the ROI to the measured impedance. Depending on the region of interest, electrode configurations using internal electrodes are between 9.8 % and 90 % better with respect to these criteria than configurations using external electrodes only. The combination of internal and external electrodes improves the focusing ability of tetrapolar impedance measurements on specific lung regions, which may be especially beneficial for lung monitoring in intensive care.

Comparison of bioimpedance analysis scan, hemoglobin and urea reduction ratio in hemodialysis patients following and not following monitoring program for improving quality of life

Science.gov (United States)

Muzasti, R. A.; Lubis, H. R.

2018-03-01

Hemodialysis (HD) is the renal replacement therapy in end-stage renal disease (ESRD), at least 2-3 times a week, impacting substantial changes in daily life. Therefore a monitoring program is needed to improve the quality of life (QoL) of HD patients. Indicators in monitoring QoL include phase angle (PhA), muscle and fat mass, and body fluid composition through Bio Scan impedance analysis (BIA) Scan, hemoglobin level, and urea reduction ratio (URR). An analytic study with the cross-sectional design was performed in 168 patients at Klinik Spesialis Ginjal Hipertensi (KSGH) Rasyida, Medan to compare BIA Scan profiles, hemoglobin levels, and URR in HD patients who follow and do not follow the monitoring program for improving QoL {Program Pemantauan Peningkatan Kualitas Hidup (P3KH)}. Each variable was analyzed by independent T-test, it is significant if p <0.05. This study showed that there were differences in BMI (p = 0.006), fat mass (p = 0.010), extracellular water / intracellular water (ECW / ICW) (p = 0.046), and haemoglobin p = 0.001). Although it was better in the program group, statistically there was no difference of PhA (p = 0.136), muscle mass (p = 0.842), and URR (p = 0.232).

Electrical bioimpedance enabling prompt intervention in traumatic brain injury

Science.gov (United States)

Seoane, Fernando; Atefi, S. Reza

2017-05-01

Electrical Bioimpedance (EBI) is a well spread technology used in clinical practice across the world. Advancements in Textile material technology with conductive textile fabrics and textile-electronics integration have allowed exploring potential applications for Wearable Measurement Sensors and Systems exploiting. The sensing principle of electrical bioimpedance is based on the intrinsic passive dielectric properties of biological tissue. Using a pair of electrodes, tissue is electrically stimulated and the electrical response can be sensed with another pair of surface electrodes. EBI spectroscopy application for cerebral monitoring of neurological conditions such as stroke and perinatal asphyxia in newborns have been justified using animal studies and computational simulations. Such studies have shown proof of principle that neurological pathologies indeed modify the dielectric composition of the brain that is detectable via EBI. Similar to stroke, Traumatic Brain Injury (TBI) also affects the dielectric properties of brain tissue that can be detected via EBI measurements. Considering the portable and noninvasive characteristics of EBI it is potentially useful for prehospital triage of TBI patients where. In the battlefield blast induced Traumatic Brain Injuries are very common. Brain damage must be assessed promptly to have a chance to prevent severe damage or eventually death. The relatively low-complexity of the sensing hardware required for EBI sensing and the already proven compatibility with textile electrodes suggest the EBI technology is indeed a candidate for developing a handheld device equipped with a sensorized textile cap to produce an examination in minutes for enabling medically-guided prompt intervention.

Detection of needle to nerve contact based on electric bioimpedance and machine learning methods.

Science.gov (United States)

Kalvoy, Havard; Tronstad, Christian; Ullensvang, Kyrre; Steinfeldt, Thorsten; Sauter, Axel R

2017-07-01

In an ongoing project for electrical impedance-based needle guidance we have previously showed in an animal model that intraneural needle positions can be detected with bioimpedance measurement. To enhance the power of this method we in this study have investigated whether an early detection of the needle only touching the nerve also is feasible. Measurement of complex impedance during needle to nerve contact was compared with needle positions in surrounding tissues in a volunteer study on 32 subjects. Classification analysis using Support-Vector Machines demonstrated that discrimination is possible, but that the sensitivity and specificity for the nerve touch algorithm not is at the same level of performance as for intra-neuralintraneural detection.

Bioimpedancia vectorial y espectroscópica: valoración del estado de hidratación con ambos métodos en hemodiálisis Bioimpedance vector and spectroscopic analysis: assessing hydration status using both methods in haemodialysis

Directory of Open Access Journals (Sweden)

Ruth Ros Nogales

2013-03-01

de hiperhidratación prediálisis tienen una equivalencia aceptable y sus resultados pueden ser intercambiables.Bioimpedance analysis is a useful tool for determining the nutritional and hydration status of haemodialysis patients. The two most commonly used systems are bioimpedance vector single frequency analysis and bioimpedance spectroscopic multiple frequency analysis, which use different criteria to classify the hydration status of the dialysed patient. The single frequency bioimpedance vector system uses a scale of 7 points ranging from a value of 3 (most hydration to a value of -3 (most dehydration, defining hyperhydration when the vector is on the hydration axis below the tolerance ellipse of 75% (values 3 and 2 on the scale. Multi-frequency spectroscopy uses two criteria to define the pre-dialysis state of hyperhydration: OH more than 2.5 litres or more than 15% of the extracellular water volume. The aim of this study was to analyse the degree of concordance between the two systems of bioimpedance in defining the state of hyperhydration of haemodialysis patients. A transversal study was carried out on 54 patients undergoing haemodialysis, performing a bioimpedance analysis with single frequency vector and multi-frequency spectroscopic monitors immediately before a haemodialysis session. The degree of equivalence in the definition of hyperhydration between the two monitors was greater when the criterion of OH>15% of extracellular water was used in the multi-frequency monitor (kappa index 0.81, excellent concordance than when the criterion of OH>2.5 litres was used (kappa index 0.71, acceptable concordance. Conclusions: There is a good relationship between the hydration vector scale and OH value (excess hydration. The criteria used by the single-frequency vector and multi-frequency spectroscopic monitors show acceptable equivalence and their results can be interchangeable.

Species of lichenized and allied fungi new to Białowieża Large Forest (NE Poland

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Krystyna Czyżewska

2014-08-01

Full Text Available The paper presents 38 species of lichenized and allied fungi new to Białowieża Large Forest. 24 taxa of lichenized Ascomycota and 14 taxa of lichenicolous and saprobic fungi are the result of the analysis of collected materials as well as additional field studies.

QUALITY OF LIFE AND NUTRITIONAL STATUS ASSESSED BY MULTIFREQUENCY BIOIMPEDANCE SPECTROSCOPY IN HEMODIALYSIS VERSUS PERITONEAL DIALYSIS PATIENTS

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Somchai Yongsiri

2012-06-01

In conclusion, quality of life and Nutritional status were not difference between PD and HD patients. PD patients had more over hydration and ECW to ICW ratio as assessed by bioimpedance spectroscopy.

Lecture notes on: Electrical theory behind the measurement of body fluids with bioimpedance spectroscopy (BIS)

DEFF Research Database (Denmark)

Jødal, Lars

The lecture notes describe how body fluid volumes can be measured/estimated using the technique bio-impedance spectroscopy (BIS). The opening chapters assume little or none technical/mathematical knowledge and can hopefully be read by anyone interested in the techneque. Later chapters become more...

25 CFR 170.807 - What must BIA include when it develops an IRR Transportation Facilities Maintenance Management...

Science.gov (United States)

2010-04-01

... Transportation Facilities Maintenance Management System? 170.807 Section 170.807 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.807 What must BIA include when it develops an IRR Transportation Facilities Maintenance Management System...

A massa gorda de risco afeta a capacidade aeróbia de jovens adolescentes

Directory of Open Access Journals (Sweden)

Luís Massuça

2013-12-01

Full Text Available OBJETIVO: Estudar o comportamento do sexo e os efeitos da idade e da massa gorda sobre a capacidade aeróbia de jovens adolescentes. MÉTODOS: Os 621 estudantes do ensino secundário participantes no estudo (14 aos 17 anos; feminino: n = 329, idade, 15,84 ± 0,92 anos; masculino: n = 292, idade, 15,82 ± 0,87 anos foram avaliados em duas categorias: morfologia (altura, peso e % massa gorda - %MG e aptidão física (capacidade aeróbia. As medições antropométricas foram realizadas de acordo com o protocolo descrito por Marfell-Jones e a %MG foi calculada por bioimpedância. A avaliação da capacidade aeróbia foi realizada com o teste aeróbio de corrida - PACER, e VO2máx relativo foi calculado utilizando a equação de Léger. Os resultados das avaliações foram classificados de acordo com os valores normativos das tabelas de referência da bateria de testes FITNESSGRAM® As técnicas estatísticas utilizadas foram: 1 cálculo de frequências; 2 teste t de Student para amostras independentes; e 3 ANOVA two-way seguida do teste post-hoc HSD de Bonferroni. RESULTADOS: 1 existem diferenças significativas entre sexos no que se refere à %MG e ao VO2máx; 2 durante a adolescência, o VO2máx estabiliza nos rapazes e sofre um declínio nas moças; 3 independentemente do sexo, a classe de %MG e a idade cronológica têm um efeito significativo sobre a capacidade aeróbia; e 4 em jovens adolescentes, com %MG de risco, a redução da %MG para níveis saudáveis parece resultar na melhoria da capacidade aeróbia. CONCLUSÃO: O impacto da %MG na capacidade aeróbia, reforça a importância da educação física escolar na promoção da saúde cardiovascular.

25 CFR 103.39 - When will BIA refuse to pay all or part of a lender's claim?

Science.gov (United States)

2010-04-01

... to liquidate loan collateral, and: (1) The lender has not made a reasonable effort to liquidate all... from collateral liquidation proceeds applied to the loan balance; or (e) The lender has otherwise... ACTIVITIES LOAN GUARANTY, INSURANCE, AND INTEREST SUBSIDY Default and Payment by BIA § 103.39 When will BIA...

Dry weight assessment by combined ultrasound and bioimpedance monitoring in low cardiovascular risk hemodialysis patients: a randomized controlled trial.

Science.gov (United States)

Siriopol, Dimitrie; Onofriescu, Mihai; Voroneanu, Luminita; Apetrii, Mugurel; Nistor, Ionut; Hogas, Simona; Kanbay, Mehmet; Sascau, Radu; Scripcariu, Dragos; Covic, Adrian

2017-01-01

Fluid overload is associated with adverse outcomes in hemodialysis (HD) patients. The precise assessment of hydration status in HD patients remains a major challenge for nephrologists. Our study aimed to explore whether combining two bedside methods, lung ultrasonography (LUS) and bioimpedance, may provide complementary information to guide treatment in specific HD patients. In total, 250 HD patients from two dialysis units were included in this randomized clinical trial. Patients were randomized 1:1 to have a dry weight assessment based on clinical (control) or LUS with bioimpedance in case of clinical hypovolemia (active)-guided protocol. The primary outcome was to assess the difference between the two groups on a composite of all-cause mortality and first cardiovascular event (CVE)-including death, stroke, and myocardial infarction. During a mean follow-up period was 21.3 ± 5.6 months, there were 54 (21.6%) composite events in the entire population. There was a nonsignificant 9% increase in the risk of this outcome in the active arm (HR = 1.09, 95% CI 0.64-1.86, p = 0.75). Similarly, there were no differences between the two groups when analyzing separately the all-cause mortality and CVE outcomes. However, patients in the active arm had a 19% lower relative risk of pre-dialytic dyspnea (rate ratio-0.81, 95% CI 0.68-0.96), but a 26% higher relative risk of intradialytic cramps (rate ratio-1.26, 95% CI 1.16-1.37). This study shows that a LUS-bioimpedance-guided dry weight adjustment protocol, as compared to clinical evaluation, does not reduce all-cause mortality and/or CVE in HD patients. A fluid management protocol based on bioimpedance with LUS on indication might be a better strategy.

Time dependence of electrical bioimpedance on porcine liver and kidney under a 50 Hz ac current

International Nuclear Information System (INIS)

Spottorno, J; Rivero, G; Venta, J de la; Multigner, M; Alvarez, L; Santos, M

2008-01-01

The purpose of this work is to study the changes of the bioimpedance from its 'in vivo' value to the values measured in a few hours after the excision from the body. The evolution of electrical impedance with time after surgical extraction has been studied on two porcine organs: the liver and the kidney. Both in vivo and ex vivo measurements of electrical impedance, measuring its real and imaginary components, have been performed. The in vivo measurements have been carried out with the animal anaesthetized. The ex vivo measurements have been made more than 2 h after the extraction of the organ. The latter experiment has been carried out at two different stabilized temperatures: at normal body temperature and at the standard preservation temperature for transplant surgery. The measurements show a correlation between the biological evolution and the electrical bioimpedance of the organs, which increases from its in vivo value immediately after excision, multiplying its value by 2 in a few hours

Time dependence of electrical bioimpedance on porcine liver and kidney under a 50 Hz ac current

Energy Technology Data Exchange (ETDEWEB)

Spottorno, J; Rivero, G; Venta, J de la [Instituto de Magnetismo Aplicado (ADIF-UCM-CSIC), PO Box 155, Las Rozas, Madrid 28230 (Spain); Multigner, M [Departamento de Fisica de Materiales, UCM, Ciudad Universitaria, 28040 Madrid (Spain); Alvarez, L; Santos, M [Centro de Investigacion Biomedica en Red en BioingenierIa, Biomateriales y Nanomedicina (CIBER-BBN), Madrid (Spain)

2008-03-21

The purpose of this work is to study the changes of the bioimpedance from its 'in vivo' value to the values measured in a few hours after the excision from the body. The evolution of electrical impedance with time after surgical extraction has been studied on two porcine organs: the liver and the kidney. Both in vivo and ex vivo measurements of electrical impedance, measuring its real and imaginary components, have been performed. The in vivo measurements have been carried out with the animal anaesthetized. The ex vivo measurements have been made more than 2 h after the extraction of the organ. The latter experiment has been carried out at two different stabilized temperatures: at normal body temperature and at the standard preservation temperature for transplant surgery. The measurements show a correlation between the biological evolution and the electrical bioimpedance of the organs, which increases from its in vivo value immediately after excision, multiplying its value by 2 in a few hours.

25 CFR Appendix A to Subpart G - List of Activities Eligible for Funding Under BIA Transportation Facility Maintenance Program

Science.gov (United States)

2010-04-01

... Transportation Facility Maintenance Program A Appendix A to Subpart G Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance Pt. 170... Transportation Facility Maintenance Program The following activities are eligible for BIA Transportation Facility...

Bioimpedance system for monitoring muscle and cardiovascular activity in the stump of lower-limb amputees

International Nuclear Information System (INIS)

Hornero, G; Díaz, D; Casas, O

2013-01-01

A bioimpedance system for the continuous measurement of non-invasive physiological parameters in lower-limb amputees is presented. The aim of the system is to monitor as many physiological parameters as possible from a single bioimpedance electrode configuration. In this way, a simple, low-cost and low-size autonomous system is developed that is able to continuously monitor the amputee in different environments (home, work, etc). The system measures both electrical impedance myography and electrical impedance plethysmography in the stump with electrodes placed in the inside face of a silicone interface. Such a system allows for the monitoring of a patient's muscle activity, and heart and breath rate, thus enabling the study and continuous monitoring of prosthesis adaptation and improvement of patient's gait to reduce physiological stress. Additionally, it can prevent cardiovascular problems due to the effort involved in the use of prostheses, which can decrease the life expectancy of amputees with previous vascular diseases. Experimental results obtained from different amputees' test validate the purpose of the system. (paper)

Precision and within- and between-day variation of bioimpedance parameters in children aged 2-14 years

DEFF Research Database (Denmark)

Andersen, Trine B; Jødal, Lars; Arveschoug, Anne

2011-01-01

BACKGROUND & AIMS: Bioimpedance spectroscopy (BIS) offers the possibility to perform rapid estimates of fluid distribution and body composition. Few studies, however, have addressed the precision and biological variation in a pediatric population. Our objectives were to evaluate precision.......4-14.9 years) had one series measured on day one (precision population). Forty-four children had a second series on day one (within-day sub-population). Thirty-two children had a series measured on the next day (between-day sub-population). Each measurement series consisted of three repeated measurements....... A linear mixed model was used for statistical analysis. RESULTS: The precision was 0.3-0.8% in children ≥6 years and 0.5-2.4% in children...

25 CFR 1000.68 - May non-BIA bureaus provide technical assistance to a Tribe/Consortium in drafting its planning...

Science.gov (United States)

2010-04-01

... Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application... Tribe/Consortium in drafting its planning grant application? 1000.68 Section 1000.68 Indians OFFICE OF... planning grant application? Yes, upon request from the Tribe/Consortium, a non-BIA bureau may provide...

25 CFR 171.420 - Can I dispose of sewage, trash, or other refuse on a BIA irrigation project?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Can I dispose of sewage, trash, or other refuse on a BIA... AND WATER IRRIGATION OPERATION AND MAINTENANCE Irrigation Facilities § 171.420 Can I dispose of sewage, trash, or other refuse on a BIA irrigation project? No. Sewage, trash, or other refuse are considered...

Dynamika kształtowania się struktury narodowościowej Białorusi po II wojnie światowej

Directory of Open Access Journals (Sweden)

Eugeniusz Mironowicz

2017-12-01

Full Text Available The dynamics of development of the ethnic structure of Belarus after World War II During the Second World War, Belarus lost more than 1.5 million inhabitants. In 1944–1946, as part of the repatriation process, 226,000 Poles left for Poland. With the construction industry in Belarus, deploying units of the Red Army and the creation of the Soviet system of government, to Belarus poured in hundreds of thousands of Russians and dozens of thousands of Ukrainians. At the same time, the Soviet authorities pursue policies conducive to resettlement Belarusians to other republics, especially to Russia. Widespread census was held every 10 years since 1959. It shows a systematic process of strengthening the Russian factor in the ethnic structure of the Belarusian Soviet Socialist Republic. This was accompanied by assimilation in Russian culture of the Belarusian youth, expelling from the countryside to the cities. The creation of the independent Belarusian state after the collapse of the Soviet Union reversed these trends. The percentage of people declaring Russian nationality, but also Jewish, Ukrainian and Polish, began to rapidly decline in the ethnic structure. This was accompanied, however, by a stronger presence of the Russian language, both in the public and private life of people in Belarus.   Dynamika kształtowania się struktury narodowościowej Białorusi po II wojnie światowej W czasie II wojny światowej Białoruś utraciła ponad 1,5 mln mieszkańców. W latach 1944–1946 w ramach akcji repatriacyjnej do Polski wyjechało 226 tys. Polaków. Wraz z budową przemysłu na Białorusi, rozmieszczaniem jednostek Armii Czerwonej i tworzeniem radzieckiego systemu władzy do Białorusi napływały setki tysięcy Rosjan i dziesiątki tysięcy Ukraińców. Jednocześnie władze radzieckie prowadziły politykę sprzyjającą przesiedlaniu Białorusinów do innych republik, a zwłaszcza do Rosji. Powszechne spisy ludności organizowane co 10 lat od

Development of a Stair-Step Multifrequency Synchronized Excitation Signal for Fast Bioimpedance Spectroscopy

Science.gov (United States)

Bian, He; Du, Fangling; Sun, Qiang

2014-01-01

Wideband excitation signal with finite prominent harmonic components is desirable for fast bioimpedance spectroscopy (BIS) measurements. This work introduces a simple method to synthesize and realize a type of periodical stair-step multifrequency synchronized (MFS) signal. The Fourier series analysis shows that the p-order MFS signal f(p, t) has constant 81.06% energy distributed equally on its p  2nth primary harmonics. The synthesis principle is described firstly and then two examples of the 4-order and 5-order MFS signals, f(4, t) and f(5, t), are synthesized. The method to implement the MFS waveform based on a field-programmable gate array (FPGA) and a digital to analog converter (DAC) is also presented. Both the number and the frequencies of the expected primary harmonics can be adjusted as needed. An impedance measurement experiment on a RC three-element equivalent model is performed, and results show acceptable precision, which validates the feasibility of the MFS excitation. PMID:24701563

Development of a Stair-Step Multifrequency Synchronized Excitation Signal for Fast Bioimpedance Spectroscopy

Directory of Open Access Journals (Sweden)

Yuxiang Yang

2014-01-01

Full Text Available Wideband excitation signal with finite prominent harmonic components is desirable for fast bioimpedance spectroscopy (BIS measurements. This work introduces a simple method to synthesize and realize a type of periodical stair-step multifrequency synchronized (MFS signal. The Fourier series analysis shows that the p-order MFS signal f(p,t has constant 81.06% energy distributed equally on its p  2nth primary harmonics. The synthesis principle is described firstly and then two examples of the 4-order and 5-order MFS signals, f(4,t and f(5,t, are synthesized. The method to implement the MFS waveform based on a field-programmable gate array (FPGA and a digital to analog converter (DAC is also presented. Both the number and the frequencies of the expected primary harmonics can be adjusted as needed. An impedance measurement experiment on a RC three-element equivalent model is performed, and results show acceptable precision, which validates the feasibility of the MFS excitation.

Impact of the Pb and Zn ore mining industry on the pollution of the Biała Przemsza River, Poland.

Science.gov (United States)

Jabłońska-Czapla, Magdalena; Nocoń, Katarzyna; Szopa, Sebastian; Łyko, Aleksandra

2016-05-01

The development of mining and metallurgic industries of Pb and Zn ores in the Biała Przemsza catchment area has had a strong influence on the condition of the surface water and bottom sediments. In the following study, total contents of metals and metalloids were researched in the water and bottom sediment samples from the Biała Przemsza River. The samples were collected monthly in 2014 at five sampling points along the river. The research helped to determine correlations between the parameters and components of the water environment (metals/metalloids, cations/anions, pH, Eh, conductivity, carbon (TOC, IC, TC), and suspension). The contents of metals and metalloids were determined with inductively coupled plasma-mass spectrometry (ICP-MS), whereas anions and cations were investigated with ion chromatography (IC). The simplified Community Bureau of Reference (BCR) three-step sequential chemical extraction was performed on Biała Przemsza River bottom sediments collected in April, July, and October. At its lower course, the Biała Przemsza River water did not meet the Polish surface water quality standards. The Biała Przemsza River water is mainly loaded with metals. Toxic concentrations of Cd, Pb, and Zn were observed at sampling points in Okradzionów and Sławków. The toxic Tl concentration was exceeded (2-6 μg/L) at three sampling points. The Biała Przemsza River bottom sediments were composed mostly of medium and fine sand. The BCR extraction of the bottom sediments demonstrated that Cd and Zn were bound to cations/anions and carbonates loosely adsorbed on the bottom sediments in spring and summer. Such a situation was observed at all the sampling points, except for BP3 in Okradzionów. The organic carbon concentration increased along the river course.

Wykrywanie białka prionu w płynach ustrojowych – nowe perspektywy w diagnostyce choroby Creutzfeldta-Jakoba

Directory of Open Access Journals (Sweden)

Ewa Golańska

2013-11-01

Full Text Available Choroba Creutzfeldta-Jakoba (Creutzfeldt-Jakob disease, CJD należy do grupy chorób wywołanych przez priony, których diagnostyka nastręcza trudności ze względu na brak nieinwazyjnych metod umożliwiających przyżyciowe definitywne rozpoznanie. Rutynowe badania laboratoryjne wspomagające diagnostykę polegają na oznaczaniu obecności białka 14-3-3 w płynie mózgowo-rdzeniowym. Białko to jest jednak jedynie nieswoistym markerem rozpadu neuronów. Również badania obrazowe oraz EEG są niewystarczające do pewnego potwierdzenia rozpoznania. Obecnie duże nadzieje wiąże się z rozwojem czułych i swoistych metod wykrywania śladowych ilości nieprawidłowych konformerów białka PrPSc – markera jednoznacznie związanego z chorobami wywołanymi przez priony – znajdujących się w płynie mózgowo-rdzeniowym lub krwi chorych z CJD. W artykule omówiono opracowane w ostatnich latach metody, w których wykorzystuje się zdolność białka prionu do indukowania przekształcenia struktury przestrzennej cząsteczek PrPc w patologiczną izoformę PrPSc. Największe nadzieje na praktyczne zastosowanie budzi obecnie metoda konwersji indukowanej przez wytrząsanie (quaking-induced conversion, QuIC, oparta na amplifikacji nieprawidłowych konformerów białka prionu w warunkach in vitro z zastosowaniem oczyszczonego zrekombinowanego białka PrPc jako substratu. Omówiono zasadę metody, wyniki najnowszych badań nad jej optymalizacją oraz perspektywy wykorzystania w celach diagnostycznych i naukowych.

25 CFR 161.610 - What will BIA do if livestock is not removed when a permit expires or is cancelled?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What will BIA do if livestock is not removed when a permit expires or is cancelled? 161.610 Section 161.610 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... will BIA do if livestock is not removed when a permit expires or is cancelled? If the livestock is not...

[HAS budget impact analysis guidelines: A new decision-making tool].

Science.gov (United States)

Ghabri, Salah; Poullié, Anne-Isabelle; Autin, Erwan; Josselin, Jean-Michel

2017-10-02

Budget impact analysis (BIA) provides short and medium-term estimates on changes in budgets and resources resulting from the adoption of new health interventions. The objective of this article is to present the main messages of the newly developed French National Authority for Health (HAS) guidelines on budget impact analysis : issues, recommendations and perspectives. The HAS guidelines development process was based on data derived from a literature review on BIA (search dates : January 2000 to June 2016), an HAS retrospective investigation, a public consultation, international expert advice, and approval from the HAS Board and the Economic and Public Health Evaluation Committee. Based on its research findings, HAS developed its first BIA guidelines, which include recommendations on the following topics : BIA definition, perspective, populations, time horizon, compared scenarios, budget impact models, costing, discounting, choice of clinical data, reporting of results and uncertainty analysis. The HAS BIA guidelines are expected to enhance the usefulness of BIA as an essential part of a comprehensive economic assessment of healthcare interventions, which itself includes cost-effectiveness analysis and equity of access to healthcare.

Bioimpedance in monitoring of effects of selective serotonin reuptake inhibitor treatment

Directory of Open Access Journals (Sweden)

Kuznecova LV

2011-06-01

Full Text Available Vasiliy Grigorievich Alexeev, Ludmila Vasilievna KuznecovaDepartment of Physiology, SP Botkin Moscow City Clinical Hospital, Moscow, RussiaBackground: Bioimpedance has been shown to be a safe technique when used in a number of biomedical applications. In this study, we used the Electro Interstitial Scan (EIS to perform bioimpedance measurements to follow up the efficacy of selective serotonin reuptake inhibitor (SSRI treatment in subjects diagnosed to have major depressive disorder.Methods: We recruited 59 subjects (38 women, 21 men aged 17–76 (mean 47 years diagnosed with major depressive disorder by psychiatric assessment at the Botkin Hospital according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV. Baseline Clinical Global Impression scores and EIS (electrical conductivity and dispersion α parameter measurements were done before starting SSRI therapy. Treatment follow-up was undertaken using EIS bioimpedance measurements and by treatment response based on the Hamilton Depression Scale and Clinical Global Impression, every 15 days for 60 days. At day 45, we classified the patients into two groups, ie, Group 1, including treatment responders, and Group 2, including nonresponders. At day 60, patients were classified into two further groups, ie, Group 3, comprising treatment responders, and Group 4, comprising nonresponders.Results: Comparing Group 1 and Group 2, electrical conductivity measurement of the pathway between the two forehead electrodes had a specificity of 72% and a sensitivity of 85.3% (P < 0.0001, with a cutoff >4.32. Comparing Group 3 and Group 4, electrical conductivity measurements in the same pathway had a specificity of 47.6% and a sensitivity of 76.3% (P < 0.16, with a cutoff >5.92. Comparing Group 1 and Group 2, the electrical dispersion α parameter of the pathway between the two disposable forehead electrodes had a specificity of 80% and a sensitivity of 85.2% (P < 0.0001 with a

Reduction of anisotropy influence and contacting effects in in-vitro bioimpedance measurements

International Nuclear Information System (INIS)

Guermazi, M; Kanoun, O; Derbel, N

2013-01-01

Experimental procedure is a decisive part in in-vitro bioimpedance measurement in order to get reproducible measurements. An electrode configuration is proposed to avoid several disadvantages produced by needle electrodes and circular non-penetrating electrode. The proposed electrode geometry reduces the influence of anisotropy and allows simultaneously a good probe contacting. We propose an experimental method to avoid the appearance of bacteria and to reduce water loss in meat during experiment post-mortem. The results show that electrode configuration with the developed experimental method have ensured reproducible measurements during a long period of 14 days post-mortem.

Reduction of anisotropy influence and contacting effects in in-vitro bioimpedance measurements

Science.gov (United States)

Guermazi, M.; Kanoun, O.; Derbel, N.

2013-04-01

Experimental procedure is a decisive part in in-vitro bioimpedance measurement in order to get reproducible measurements. An electrode configuration is proposed to avoid several disadvantages produced by needle electrodes and circular non-penetrating electrode. The proposed electrode geometry reduces the influence of anisotropy and allows simultaneously a good probe contacting. We propose an experimental method to avoid the appearance of bacteria and to reduce water loss in meat during experiment post-mortem. The results show that electrode configuration with the developed experimental method have ensured reproducible measurements during a long period of 14 days post-mortem.

Bioimpedance index for measurement of total body water in severely malnourished children

DEFF Research Database (Denmark)

Girma, Tsinuel; Kæstel, Pernille; Workeneh, Netsanet

2016-01-01

BACKGROUND & OBJECTIVES: Restoration of body composition indicates successful management of severe acute malnutrition (SAM). Bioimpedance (BI) index (height(2)/resistance) is used to predict total body water (TBW) but its performance in SAM, especially with oedema, requires further investigation....... SUBJECTS/METHODS: Children with SAM (mid-arm circumference ...Hzs. Pre- and post-deuterium dose saliva samples were analysed using isotope-ratio mass spectrometry. TBW was regressed on H(2)/Z. Xc and R were height (H)-indexed, and Xc/H plotted against R/H. RESULTS: Thirty five children (16 non-oedematous and 19 oedematous) with median (interquartile range) age of 42...

25 CFR 115.423 - If you are a custodial parent, a legal guardian, or an emancipated minor, may BIA authorize the...

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false If you are a custodial parent, a legal guardian, or an emancipated minor, may BIA authorize the disbursement of funds from a minor's supervised account without your... custodial parent, a legal guardian, or an emancipated minor, may BIA authorize the disbursement of funds...

25 CFR 115.605 - What information will the BIA include in its notice of the decision to restrict your IIM account?

Science.gov (United States)

2010-04-01

...: Hearing Process for Restricting an IIM Account § 115.605 What information will the BIA include in its... notice of its decision to restrict your account, the only information the public notice will include is... 25 Indians 1 2010-04-01 2010-04-01 false What information will the BIA include in its notice of...

Validity of Bioelectrical Impedance Analysis to Estimation Fat-Free Mass in the Army Cadets.

Science.gov (United States)

Langer, Raquel D; Borges, Juliano H; Pascoa, Mauro A; Cirolini, Vagner X; Guerra-Júnior, Gil; Gonçalves, Ezequiel M

2016-03-11

Bioelectrical Impedance Analysis (BIA) is a fast, practical, non-invasive, and frequently used method for fat-free mass (FFM) estimation. The aims of this study were to validate predictive equations of BIA to FFM estimation in Army cadets and to develop and validate a specific BIA equation for this population. A total of 396 males, Brazilian Army cadets, aged 17-24 years were included. The study used eight published predictive BIA equations, a specific equation in FFM estimation, and dual-energy X-ray absorptiometry (DXA) as a reference method. Student's t-test (for paired sample), linear regression analysis, and Bland-Altman method were used to test the validity of the BIA equations. Predictive BIA equations showed significant differences in FFM compared to DXA (p FFM variance. Specific BIA equations showed no significant differences in FFM, compared to DXA values. Published BIA predictive equations showed poor accuracy in this sample. The specific BIA equations, developed in this study, demonstrated validity for this sample, although should be used with caution in samples with a large range of FFM.

Analysis of activity in swine producers group based on agricultural producers association in Biała district

Directory of Open Access Journals (Sweden)

Damian Knecht

2013-03-01

Full Text Available The process of pigs producer groups formation in Poland is quite dynamic. Currently on the pork market 181 groups operate, which includes about 4000 swine producers. The aim of this study was to characterize the activities of the Agricultural Producers Association in Biała District. The research tool was a personal questionnaire and the research sample consisted of 30 farmers. It has been shown that after joining the producers group, the investigated households reported an increase in sales volume and improved the flock production parameters. Majority of the respondents were not satisfied with the cooperation with meat processing companies.

POTÊNCIA E CAPACIDADE ANAERÓBIA EM ATLETAS DE KARATE

Directory of Open Access Journals (Sweden)

Keith Sato Urbinati

2011-01-01

Full Text Available O objetivo do presente estudo foi verificar o nível de potência muscular, bem como a intensidade de esforço durante prova de potência e capacidade anaeróbia em atletas de Karate. Participaram do estudo treze karatekas especialistas em prova de kumitê (luta,sexo masculino, idade média de 20,7±3,79 anos. Realizou-se a avaliação de potência e capacidade anaeróbia (Wingate test, com coleta das variáveis fisiológicas:frequência cardíaca (FC, pressão arterial (PA e lactato sanguíneo (LAC de repouso, imediatamente após e em 5 min de recuperação. Para verificar se ocorrem diferenças nas variáveis fisiológicas durante o teste, realizou-se análise de variância, post hoc de Bonferronie (p?0,05. Verificou-se potência de pico(PP de 8,77 ± 0,99 W/kg-1, potência média (PM de 5,13± 0,49 W.kg-1 e % de fadiga de 50,5 ± 6,45%. Para as variáveis fisiológicas,a FC (F=9,79; p=0,00 pós-teste de Wingate foi estatisticamente maior e diferenteda FC de repouso e recuperação. Não foram encontradas diferenças nos níveis pressatórios e nas concentrações de LAC. Em relação aos valores de FC e LAC tais variáveis pós-teste não se apresentaram elevados. Os valores de potência anaeróbia estão de acordo com a necessidade da modalidade esportiva. Assim, verificou-se menores intensidades de esforço em teste de Wingate quando comparados a de situação real de competição. O nível de potência muscular parece estar adequado ao kumitê.

Evaluación del peso seco y el agua corporal según bioimpedancia vectorial frente al método tradicional Assessing dry weight and body water using bioimpedance vector analysis compared to the traditional method

Directory of Open Access Journals (Sweden)

María Teresa Centellas Tristán

2013-03-01

, los resultados mostraron variaciones poco significativas de los parámetros estudiados. Conclusiones: Aunque la bioimpedancia aporta conocimientos más exactos sobre la composición hídrica corporal y la distribución del agua, el peso seco establecido por estimación clínica sigue siendo de gran valor. La bioimpedancia ayuda a detectar pequeños cambios subclínicos, que podrían tener trascendencia a más largo plazo. La bioimpedancia pone de manifiesto de forma objetiva la desnutrición presente en casi la mitad de pacientes de hemodiálisis.Introduction: Electrical bioimpedance can be used to establish the hydration and nutritional state in haemodialysis. Assessing the hydration status of patients is habitually done as a "clinical art" using the concept of "dry weight". There are few studies that examine the concordance between dry weight estimated clinically and the dry weight deduced post-bioimpedance analysis. Material and methods: 36 patients were studied (26 men and 10 women. Electrical bioimpedance vector analysis was performed before and 30' after midweek dialysis, measuring weight, total water and its distribution, phase angle, Na/K ratio, and the position of each patient's vector in the sphere normogram: percentiles 50.75 and 95. Dry weight was estimated according to the subjective assessment of the nephrologist, nurse and patient. Furthermore, in 12 stable patients the bioimpedance analysis continued for 4 weeks. Results: The age was 69.6±12.5 (r=29-89. Weight was 73.1±14.1 predialysis, and 70.4±13.6 postdialysis. Total body water was 24.7±2.8 L/m (53.7±8.2% of weight; 22.1±3.0 L (56.2±5.9% of weight corresponded to extracellular water and 17.4±3.8 L/m to intracellular water. Following haemodialysis, total water fell to 22.8±2.4 L/m (51.8±8.6% of weight (23.5±2.2 L in men; and 21.5±3 L in women of which 19.6±2.5 L (54.3±5.8% of weight corresponded to extracellular water and 16.7±3.3 to intracellular water. One man and 5 women exceeded

BIA and DOD Schools: Student Achievement and Other Characteristics Often Differ from Public Schools

National Research Council Canada - National Science Library

2001-01-01

...) and the Department of Defense (DOD) school systems. Unlike public schools, where federal funding constitutes a small portion of total resources, the BIA and DOD school systems depend almost entirely on federal funds...

BIA AND DOD SCHOOLS: Student Achievement and Other Characteristics Often Differ from Public Schools

National Research Council Canada - National Science Library

2001-01-01

...) and the Department of Defense (DOD) school systems. Unlike public schools, where federal funding constitutes a small portion of total resources, the BIA and DOD school systems depend almost entirely on federal funds...

25 CFR 115.602 - How will the BIA notify you or your guardian, as applicable, of its decision to restrict your IIM...

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How will the BIA notify you or your guardian, as... guardian, as applicable, of its decision to restrict your IIM account? The BIA will notify you or your guardian, as applicable, of its decision to restrict your IIM account by: (a) United States certified mail...

Coupling IR Thermography and BIA to analyse body reaction after one acupuncture session

International Nuclear Information System (INIS)

Piquemal, M

2013-01-01

Coupling both thermography and bio-Impedance, some biophysical acupuncture mechanisms are statically studied on a small population of 18 subjects. Results show that a possible way of understanding acupuncture, in an electrical way, should be to consider ionic flux redistribution between vascular and extra cell compartments. This is a two steps mechanism. The first one is starting with needles insertion and the second one is lasting with more intensity after removing them from skin.

Coupling IR Thermography and BIA to analyse body reaction after one acupuncture session

Science.gov (United States)

Piquemal, M.

2013-04-01

Coupling both thermography and bio-Impedance, some biophysical acupuncture mechanisms are statically studied on a small population of 18 subjects. Results show that a possible way of understanding acupuncture, in an electrical way, should be to consider ionic flux redistribution between vascular and extra cell compartments. This is a two steps mechanism. The first one is starting with needles insertion and the second one is lasting with more intensity after removing them from skin.

Evaluation of body adiposity index (BAI) to estimate percent body fat in an indigenous population.

Science.gov (United States)

Kuhn, Patricia C; Vieira Filho, João Paulo B; Franco, Luciana; Dal Fabbro, Amaury; Franco, Laercio J; Moises, Regina S

2014-04-01

The aim of this study was to evaluate the usefulness of Body Adiposity Index (BAI) as a predictor of body fat in Xavante Indians and to investigate which anthropometric measures of adiposity best correlate with body fat in this population. We evaluated 974 individuals (476 male), aged 42.3 ± 19.5 years. Percentage of body fat (%BF) determined by bioimpedance analysis (BIA) was used as the reference measure of adiposity. Bland-Altman analysis was used to assess the agreement between the two methods: BAI and BIA. Associations between anthropometric measures of adiposity were investigated by Pearson correlation analysis. BAI overestimates %BF (mean difference: 4.10%), mainly at lower levels of adiposity. Significant correlations were found between %BF and all measurements, being the strongest correlation with BAI. However, stratified analyses according to gender showed that among men waist circumference has the strongest correlation (r = 0.73, p < 0.001) and among women BAI (r = 0.71, p < 0.001), BMI (r = 0.69, p < 0.001) and waist circumference (r = 0.70, p < 0.001) performed similarly. BAI can be a useful tool to predict %BF in Xavante Indians, although it has some limitations. However, it is not a better predictor of adiposity than waist circumference in men or BMI and waist circumference in women. Copyright © 2013 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Muscle development in healthy children evaluated by bioelectrical impedance analysis.

Science.gov (United States)

Uchiyama, Tomoka; Nakayama, Takahiro; Kuru, Satoshi

2017-02-01

This study aimed to use bioelectrical impedance analysis (BIA) to generate a new muscle density index (MDI), the MDI_BIA, to evaluate muscle development, and to demonstrate the changes that occur in the BIA-based muscle cross-sectional area index (MCAI_BIA) that accompany growth. We also sought to determine the traceability of chronological changes in the MDI_BIA and MCAI_BIA. Healthy children (n=112) aged 8.68±3.16years (0.33-14.00years) underwent bioelectrical impedance (BI) measurements of their upper arms, thighs, and lower legs. The MDI_BIA and MCAI_BIA were calculated, and cross-sectional investigations were conducted into the changes in these indices that accompanied growth. Data collected after 1.10±0.08years from 45 participants determined the traceability of the chronological changes in the MDI_BIA and MCAI_BIA. The MDI_BIA and MCAI_BIA were significantly positively correlated with age and height at all locations (Pchildren, and they showed significant chronological increases. Hence, these indices could be used to represent muscle development and muscle mass increases. BIA is non-invasive, convenient, and economical and it may be useful in evaluating muscle development and muscle cross-sectional areas in children. Copyright © 2016 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

Validity of Bioelectrical Impedance Analysis to Estimation Fat-Free Mass in the Army Cadets

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Raquel D. Langer

2016-03-01

Full Text Available Background: Bioelectrical Impedance Analysis (BIA is a fast, practical, non-invasive, and frequently used method for fat-free mass (FFM estimation. The aims of this study were to validate predictive equations of BIA to FFM estimation in Army cadets and to develop and validate a specific BIA equation for this population. Methods: A total of 396 males, Brazilian Army cadets, aged 17–24 years were included. The study used eight published predictive BIA equations, a specific equation in FFM estimation, and dual-energy X-ray absorptiometry (DXA as a reference method. Student’s t-test (for paired sample, linear regression analysis, and Bland–Altman method were used to test the validity of the BIA equations. Results: Predictive BIA equations showed significant differences in FFM compared to DXA (p < 0.05 and large limits of agreement by Bland–Altman. Predictive BIA equations explained 68% to 88% of FFM variance. Specific BIA equations showed no significant differences in FFM, compared to DXA values. Conclusion: Published BIA predictive equations showed poor accuracy in this sample. The specific BIA equations, developed in this study, demonstrated validity for this sample, although should be used with caution in samples with a large range of FFM.

Functional Characterization of 4´OMT and 7OMT Genes in BIA Biosynthesis

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Tugba eGurkok

2016-02-01

Full Text Available Alkaloids are diverse group of secondary metabolites generally found in plants. Opium poppy (Papaver somniferum L., the only commercial source of morphinan alkaloids, has been used as a medicinal plant since ancient times. It produces benzylisoquinoline alkaloids (BIA including the narcotic analgesic morphine, the muscle relaxant papaverine, and the anti-cancer agent noscapine. Though BIAs play crucial roles in many biological mechanisms their steps in biosynthesis and the responsible genes remain to be revealed. In this study, expressions of 3-hydroxy-N-methylcoclaurine 4´-O-methyltransferase (4´OMT and reticuline 7-O-methyltransferase (7OMT genes were subjected tomanipulation to functionally characterize their roles in BIA biosynthesis. Measurements of alkaloid accumulation were performed in leaf, stem and capsule tissues accordingly. Suppression of 4´OMT expression caused reduction in the total alkaloid content in stem tissue whereas total alkaloid content was significantly induced in the capsule. Silencing of the 7OMT gene also caused repression in total alkaloid content in the stem. On the other hand, over-expression of 4´OMT and 7OMT resulted in higher morphine accumulation in the stem but suppressed amount in the capsule. Moreover, differential expression in several BIA synthesis genes (CNMT, TYDC, 6OMT, SAT, COR, 4´OMT and 7OMT were observed upon manipulation of 4´OMT and 7OMT expression. Upon silencing and overexpression applications, tissue specific effects of these genes were identified. Manipulation of 4´OMT and 7OMT genes caused differentiated accumulation of BIAs including morphine and noscapine in capsule and stem tissues.

Monitoring Change of Body Fluid during Physical Exercise using Bioimpedance Spectroscopy and Finite Element Simulations

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Lisa Röthlingshöfer

2011-12-01

Full Text Available Athletes need a balanced body composition in order to achieve maximum performance. Especially dehydration reduces power and endurance during physical exercise. Monitoring the body composition, with a focus on body fluid, may help to avoid reduction in performance and other health problems.For this, a potential measurement method is bioimpedance spectroscopy (BIS. BIS is a simple, non-invasive measurement method that allows to determine different body compartments (body fluid, fat, fat-free mass. However, because many physiological changes occur during physical exercise that can influence impedance measurements and distort results, it cannot be assumed that the BIS data are related to body fluid loss alone.To confirm that BIS can detect body fluid loss due to physical exercise, finite element (FE simulations were done. Besides impedance, also the current density contribution during a BIS measurement was modeled to evaluate the influence of certain tissues on BIS measurements.Simulations were done using CST EM Studio (Computer Simulation Technology, Germany and the Visible Human Data Set (National Library of Medicine, USA. In addition to the simulations, BIS measurements were also made on athletes. Comparison between the measured bioimpedance data and simulation data, as well as body weight loss during sport, indicates that BIS measurements are sensitive enough to monitor body fluid loss during physical exercise.doi:10.5617/jeb.178 J Electr Bioimp, vol. 2, pp. 79-85, 2011

Smart bioimpedance-controlled craniotomy: Concept and first experiments.

Science.gov (United States)

Niesche, Annegret; Müller, Meiko; Ehreiser, Fritz; Teichmann, Daniel; Leonhardt, Steffen; Radermacher, Klaus

2017-07-01

Craniotomy is part of many neurosurgical interventions to create surgical access to intracranial structures. The procedure conventionally bears a high risk of unintended dural tears or damage of the soft tissue underneath the bone. A new synergistically controlled instrument has recently been introduced to address this problem by combining a soft tissue preserving saw with an automatic cutting depth control. Many approaches are known to obtain the information required on the local bone thickness. However, they suffer from unsatisfactory robustness against disturbances occurring during surgery and many approaches require additional intra- or preoperative steps in the workflow. This article presents first concepts for real-time cutting depth control based on in-process bioimpedance measurements. Furthermore, sensor integration into a synergistic surgical device incorporating a bidirectional oscillating saw is demonstrated and evaluated in first feasibility tests on a fresh bovine bone specimen. Results of bipolar measurements show that the transition of different layers of bicortical bone and bone breakthrough lead to characteristic impedance patterns that can be used for process control.

An Annotated And Illustrated Catalogue Of Polypores (Agaricomycetes Of The Białowieża Forest (NE Poland

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Karasiński Dariusz

2015-12-01

Full Text Available The Białowieża Forest (BF is one of the best-preserved lowland deciduous and mixed forest complexes in Europe, rich in diverse fungi. This paper summarizes what is known about the poroid fungi of the Polish part of the Białowieża Forest, based on literature data, a re-examination of herbarium materials, and the authors’ studies from 1990–2014. An annotated catalogue of polypores recorded in the forest is presented, including 80 genera with 210 species. All literature and herbarium records are enumerated, and 160 species are illustrated with color pictures. Fourteen species previously reported in the literature have uncertain status because they lack voucher specimens and were not confirmed in recent field studies. Antrodiella subradula (Pilát Niemelä & Miettinen, previously known from Asia, is reported for the first time from Europe. Fourteen species are newly reported from the Białowieża Forest (mainly from Białowieża National Park, including 8 species with first records in Poland (Antrodia hyalina Spirin, Miettinen & Kotir., Antrodia infirma Renvall & Niemelä, Antrodiella subradula, Junghuhnia fimbriatella (Peck Ryvarden, Postia folliculocystidiata (Kotl. & Vampola Niemelä & Vampola, Postia minusculoides (Pilát ex Pilát Boulet, Skeletocutis chrysella Niemelä, Skeletocutis papyracea A. David, and 6 species reported previously from other localities in Poland [Antrodiella faginea Vampola & Pouzar, Dichomitus campestris (Quél. Domański & Orlicz, Loweomyces fractipes (Berk. & M. A. Curtis Jülich, Oxyporus latemarginatus (Durieu & Mont. Donk, Perenniporia narymica (Pilát Pouzar, Phellinus nigricans (Fr. P. Karst.]. Several very rare European polypores already reported from the Białowieża Forest in the 20th century, such as Antrodia albobrunnea (Romell Ryvarden, Antrodiella foliaceodentata (Nikol. Gilb. & Ryvarden, Buglossoporus pulvinus (Pers. Donk, Dichomitus albidofuscus (Domański Domański and Gelatoporia subvermispora

BMI or BIA: Is Body Mass Index or Body Fat Mass a Better Predictor of Cardiovascular Risk in Overweight or Obese Children and Adolescents?

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Barbara Bohn

2015-04-01

Full Text Available Background: Body fat (BF percentiles for German children and adolescents have recently been published. This study aims to evaluate the association between bioelectrical impedance analysis(BIA-derived BF and cardiovascular risk factors and to investigate whether BF is better suited than BMI in children and adolescents. Methods: Data of 3,327 children and adolescents (BMI > 90th percentile were included. Spearman's correlation and receiver operating characteristics (ROCs were applied determining the associations between BMI or BF and cardiovascular risk factors (hypertension, dyslipidemia, elevated liver enzymes, abnormal carbohydrate metabolism. Area under the curve (AUC was calculated to predict cardiovascular risk factors. Results: A significant association between both obesity indices and hypertension was present (all p Conclusion: BIA-derived BF was not superior to BMI to predict cardiovascular risk factors in overweight or obese children and adolescents.

Modeling code-interactions in bilingual word recognition: Recent empirical studies and simulations with BIA+

NARCIS (Netherlands)

Lam, K.J.Y.; Dijkstra, A.F.J.

2010-01-01

Daily conversations contain many repetitions of identical and similar word forms. For bilinguals, the words can even come from the same or different languages. How do such repetitions affect the human word recognition system? The Bilingual Interactive Activation Plus (BIA+) model provides a

DETERMINAÇÃO RÁPIDA E SIMPLES DE CITRATO DE SILDENAFILA (VIAGRA® E GENÉRICOS EMPREGANDO ELETRODO IMPRESSO DE CARBONO EM SISTEMAS FIA E BIA COM DETECÇÃO AMPEROMÉTRICA

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Rafael S. Backes

Full Text Available This work presents two amperometric methods for Sildenafil Citrate (SC determination in erectile dysfunction drugs (Viagra® and Generics, using Batch Injection Analysis (BIA and Flow Injection Analysis (FIA systems with a cell for Screen Printed Electrodes (SPE. In Britton- Robinson buffer solution (pH 2, the SC presented an irreversible anodic peak at around +1.0 V vs. Ag pseudo-reference electrode, using five different working electrodes of commercial SPE. The carbon SPE (unmodified was selected as the best working electrode, providing good sensitivity, precision and low-cost. The SC amperometric detection for two proposed methods was performed at +1.1 V. The best conditions for SC determination by hydrodynamic systems were obtained through injection volumes of 50 and 150 µL at flow rates of 100 and 75 µL s-1, for BIA and FIA respectively. In these conditions, BIA system showed the best sensitivity (0.188 µA mol-1 L and theoretical analytical frequency (360 h-1 for SC determination. The repeatability studies were similar for both systems with relative standard deviation of approximately 3.0%. The SC analyses in pharmaceutical samples obtained by two proposed methods were compared to HPLC-UV method.

COMPORTAMENTO DOS SÓLIDOS TOTAIS NO PROCESSO DE DIGESTÃO ANAERÓBIA DE RESÍDUOS SÓLIDOS URBANOS E INDUSTRIAIS

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Valderi Duarte Leite

1999-08-01

Full Text Available RESUMO O processo de digestão anaeróbia pode ser aplicado para bioestabilizar uma grande variedade de substratos. Neste trabalho, empregou-se o processo de digestão anaeróbia à fração orgânica putrescível dos resíduos sólidos urbanos, tomando-se como parâmetros avaliativos os sólidos totais e os sólidos totais voláteis. O trabalho foi realizado em quatro reatores anaeróbios de batelada, com capacidade unitária de 50 L e a análise dos seus dados mostra que é possível se empregar o processo de digestão anaeróbia a esse tipo de substrato que, além de bioestabilizar a matéria orgânica putrescível, produz gás metano, que pode ser utilizado como fonte alternativa de energia para fins domésticos e industriais.

A method for the estimation of hydration state during hemodialysis using a calf bioimpedance technique.

Science.gov (United States)

Zhu, F; Kuhlmann, M K; Kotanko, P; Seibert, E; Leonard, E F; Levin, N W

2008-06-01

Although many methods have been utilized to measure degrees of body hydration, and in particular to estimate normal hydration states (dry weight, DW) in hemodialysis (HD) patients, no accurate methods are currently available for clinical use. Biochemcial measurements are not sufficiently precise and vena cava diameter estimation is impractical. Several bioimpedance methods have been suggested to provide information to estimate clinical hydration and nutritional status, such as phase angle measurement and ratio of body fluid compartment volumes to body weight. In this study, we present a calf bioimpedance spectroscopy (cBIS) technique to monitor calf resistance and resistivity continuously during HD. Attainment of DW is defined by two criteria: (1) the primary criterion is flattening of the change in the resistance curve during dialysis so that at DW little further change is observed and (2) normalized resistivity is in the range of observation of healthy subjects. Twenty maintenance HD patients (12 M/8 F) were studied on 220 occasions. After three baseline (BL) measurements, with patients at their DW prescribed on clinical grounds (DW(Clin)), the target post-dialysis weight was gradually decreased in the course of several treatments until the two dry weight criteria outlined above were met (DW(cBIS)). Post-dialysis weight was reduced from 78.3 +/- 28 to 77.1 +/- 27 kg (p hydration status. Since no current techniques have been developed to detect DW as precisely, it is suggested as a standard to be evaluated clinically.

Development of methods for body composition studies

International Nuclear Information System (INIS)

Mattsson, Soeren; Thomas, Brian J

2006-01-01

This review is focused on experimental methods for determination of the composition of the human body, its organs and tissues. It summarizes the development and current status of fat determinations from body density, total body water determinations through the dilution technique, whole and partial body potassium measurements for body cell mass estimates, in vivo neutron activation analysis for body protein measurements, dual-energy absorptiometry (DEXA), computed tomography (CT) and magnetic resonance imaging (MRI, fMRI) and spectroscopy (MRS) for body composition studies on tissue and organ levels, as well as single- and multiple-frequency bioimpedance (BIA) and anthropometry as simple easily available methods. Methods for trace element analysis in vivo are also described. Using this wide range of measurement methods, together with gradually improved body composition models, it is now possible to quantify a number of body components and follow their changes in health and disease. (review)

Development of methods for body composition studies

Energy Technology Data Exchange (ETDEWEB)

Mattsson, Soeren [Department of Radiation Physics, Lund University, Malmoe University Hospital, SE-205 02 Malmoe (Sweden); Thomas, Brian J [School of Physical and Chemical Sciences, Queensland University of Technology, Brisbane, QLD 4001 (Australia)

2006-07-07

This review is focused on experimental methods for determination of the composition of the human body, its organs and tissues. It summarizes the development and current status of fat determinations from body density, total body water determinations through the dilution technique, whole and partial body potassium measurements for body cell mass estimates, in vivo neutron activation analysis for body protein measurements, dual-energy absorptiometry (DEXA), computed tomography (CT) and magnetic resonance imaging (MRI, fMRI) and spectroscopy (MRS) for body composition studies on tissue and organ levels, as well as single- and multiple-frequency bioimpedance (BIA) and anthropometry as simple easily available methods. Methods for trace element analysis in vivo are also described. Using this wide range of measurement methods, together with gradually improved body composition models, it is now possible to quantify a number of body components and follow their changes in health and disease. (review)

Bioelectrical impedance analysis--part I

DEFF Research Database (Denmark)

Kyle, Ursula G; Bosaeus, Ingvar; De Lorenzo, Antonio D

2004-01-01

The use of bioelectrical impedance analysis (BIA) is widespread both in healthy subjects and patients, but suffers from a lack of standardized method and quality control procedures. BIA allows the determination of the fat-free mass (FFM) and total body water (TBW) in subjects without significant...

Advanced oxidation protein products — biological marker of oxidative stress = Zaawansowane produkty utleniania białek – biologiczne markery stresu oksydacyjnego

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Anna Cwynar

2016-09-01

  ABSTRACT Advanced oxidation protein products (AOPPs are mostly derivatives of oxidatively modified albumin. The results of many experimental studies confirm intensification of oxidative modifications of proteins and an increase in concentration of advanced oxidation protein products (AOPPs in different pathological conditions, particularly those with well documented involvement of oxidative stress in their etiopathogenesis, but also those where its role is not yet well understood. Currently intensive research is carried out on the possibility of using AOPPs as useful indicators for diagnosing, prognosis and monitoring of diseases.   Keywords: advanced oxidation protein products, autoimmune disease, oxidative stress   STRESZCZENIE Zaawansowane produkty utleniania białek (AOPPs, to najczęściej pochodne zmodyfikowanej oksydacyjnie albuminy. Wyniki licznych badań doświadczalnych potwierdzają nasilenie oksydacyjnych modyfikacji białek i wzrost stężenia zaawansowanych produktów utleniania białek (AOPPs w różnych stanach patologicznych, szczególnie tych o dobrze udokumentowanym udziale stresu oksydacyjnego w ich etiopatogenezie, ale także takich, w których jego rola nie jest jeszcze dobrze poznana.. Obecnie trwają intensywne badania nad możliwością wykorzystania AOPPs, jako użytecznych wskaźników do diagnozowania, prognozowania oraz monitorowania chorób.   Słowa kluczowe: zaawansowane produkty utleniania białek, choroby autoimmunologiczne, stres oksydacyjny

Zakład Medycyny Sądowej w Bielsku-Białej

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Jerzy Brzyski

2014-10-01

Full Text Available Zakład Medycyny Sądowej w Bielsku-Białej został utworzony w 1978 roku. Podstawą dla jego utworzenia i wpisania w strukturę Wojewódzkiego Szpitala Zespolonego były wytyczne Ministra Zdrowia i Opieki Społecznej z dnia 15.06.1978 roku w sprawie organizacji i zadań komórek medycyny sądowej (Dz.U. MZiOS Nr 11, poz 28.

Bioelectrical impedance analysis to estimate body composition in surgical and oncological patients: a systematic review

NARCIS (Netherlands)

Haverkort, E. B.; Reijven, P. L. M.; Binnekade, J. M.; de van der Schueren, M. A. E.; Earthman, C. P.; Gouma, D. J.; de Haan, R. J.

2015-01-01

Bioelectrical impedance analysis (BIA) is a commonly used method for the evaluation of body composition. However, BIA estimations are subject to uncertainties.The aim of this systematic review was to explore the variability of empirical prediction equations used in BIA estimations and to evaluate

Assessment of muscle mass, risk of falls and fear of falling in elderly people with diabetic neuropathy

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Hudson Azevedo Pinheiro

Full Text Available Abstract Objective : To assess muscle mass, risk of falls and fear of falling in elderly adults with diabetic neuropathy (DNP. Methods : 50 elderly patients with diabetes mellitus (DM and diabetic neuropathy (NPD participated in this study. Risk of falling was assessed using the Berg Balance Scale (BBS. Fear of falling was assessed by means of the Falls Efficacy Scale-International (FES-I. Muscle mass was assessed by tetrapolar bioimpedance analysis (BIA and Janssen's equation. Subjects were divided into two groups: one with a history of falls in the six months before study enrollment (G1 and the other without history of falls (G2. Results : There were statistically significant differences between G1 and G2 regarding lean body mass (p < 0.05, risk of falls as measured by the BBS (p < 0.01, and fear of falling as measured by the FES-I (p < 0.01. In addition, there was a significant correlation between the BBS and BIA (r = 0.45 and p < 0.01, showing that the greater the lean body mass, the lower the risk of falling. Conclusions : We found an association between lean mass, risk of falls and fear of falling in elderly adults with DNP and a history of falls from own height.

The evaluation in terms of sarcopenia of patients with fibromyalgia syndrome.

Science.gov (United States)

Koca, Irfan; Savas, Esen; Ozturk, Zeynel Abidin; Boyaci, Ahmet; Tutoglu, Ahmet; Alkan, Samet; Yildiz, Hamit; Kimyon, Gezmiş

2016-11-01

Fibromyalgia syndrome (FMS) is an extra-articular rheumatic illness, characterized by widespread body pain and decreased muscle function. Generalized loss of muscle mass and strength is named as sarcopenia. The objective of this study was to evaluate patients with FMS regarding sarcopenia. This was a cross sectional, case-controlled, single-blinded, and single-centered study. The FMS patients were assessed by Fibromyalgia Impact Questionnaire (FIQ), visual analog scale (VAS), Beck Depression Index (BDI), and Pittsburg Sleep Quality Scale (PSQI). All the participants were evaluated for sarcopenia by bioimpedance analysis (BIA), anthropometric measurements, handgrip strength, and the parameters of walking speed. In this study, 82 patients with FMS and 38 healthy control female subjects were included. VAS, BDI, and PSQI scores were statistically higher in the FMS group than the control group (p FIQ in patients was significantly correlated with BIA, waist circumference, HS, WS, and body mass index (r = 0.267, p = 0.018; r = 0.291, p = 0.010; r = - 0.319, p = 0.004; r = - 0.360, p = 0.001; and r  = 0.304, p = 0.007 respectively). Evaluation of female patients with primary FMS by the sarcopenia parameters could contribute a more objective evaluation during the patients' follow-up.

Assessment of degree of hydration in dialysis patients using whole body and calf bioimpedance analysis

Science.gov (United States)

Zhu, F.; Kotanko, P.; Handelman, G. J.; Raimann, J.; Liu, L.; Carter, M.; Kuhlmann, M. K.; Siebert, E.; Leonard, E. F.; Levin, N. W.

2010-04-01

Prescription of an appropriate post hemodialysis (HD) dialysis target weight requires accurate evaluation of the degree of hydration. The aim of this study was to investigate whether a state of normal hydration as defined by calf bioimpedance spectroscopy (cBIS) could be characterized in HD and normal subjects (NS). cBIS was performed in 62 NS (33 m/29 f) and 30 HD patients (16 m /14 f) pre- and post-dialysis to measure extracellular resistance. Normalized calf resistivity at 5 kHz (ρN,5) was defined as resistivity divided by body mass index. Measurements were made at baseline (BL) and at a state of normal hydration (NH) established following the progressive reduction of post-HD weight over successive dialysis treatments until the ρN,5 was in the range of NS. Blood pressures were measured pre- and post-HD treatment. ρN,5 in males and females differed significantly in NS (20.5±1.99 vs 21.7±2.6 10-2 Ωm3/kg, p>0.05). In patients, ρN,5 notably increased and reached NH range due to progressive decrease in body weight, and systolic blood pressure (SBP) significantly decreased pre- and post-HD between BL and NBH respectively. This establishes the use of ρN,5 as a new comparator allowing the clinician to incrementally monitor the effect of removal of extracellular fluid from patients over a course of dialysis treatments.

[EVALUATION OF THE BODY ADIPOSITY INDEX IN PREDICTING PERCENTAGE BODY FAT AMONG COLOMBIAN ADULTS].

Science.gov (United States)

González-Ruíz, Katherine; Correa-Bautista, Jorge Enrique; Ramírez-Vélez, Robinson

2015-07-01

the body adiposity index (BAI) is a new simplistic method for predicting body fat percentage (BF%) via a simple equation of hip circumference to height. Up to now, few studies have evaluated the performance of BAI in determining excess fat in Colombians. The aim of this study was to evaluate the usefulness of BAI as a predictor of body fat in among Colombian adults. cross-sectional study carried out in a sample of 204 male belonging to the education sector from Bogotá, Colombia. BAI was calculated based on the equation reported in the Bergman et al. %BF determined by tetrapolar bioimpedance analysis (BIA) was used as the reference measure of adiposity. Bland-Altman analysis was used to assess the agreement between the two methods: BAI and BIA. Associations between anthropometric measures of adiposity were investigated by Pearson correlation analysis. in general pupulation, the BAI overestimates %BF (mean difference: 12.5 % [95%CI = -4.04 % to -21.02 %]), mainly at lower levels of adiposity (mean difference: 10.2 ± 3.3). Significant correlations were found between BAI and all measurements, being the strongest-moderate correlation with %BF (r = 0.777, p Colombian adults and has a tendency to provide overestimated values as BF% decreases. Therefore, this method can be a useful tool to predict %BF in Colombian adults, although it has some limitations. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

25 CFR 170.805 - What are the local, tribal, and BIA roles in transportation facility maintenance?

Science.gov (United States)

2010-04-01

... transportation facility maintenance? 170.805 Section 170.805 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.805 What are the local... Road Maintenance dollars. ...

Analysis of association of gene variants with obesity traits in New Zealand European children at 6 years of age.

Science.gov (United States)

Krishnan, Mohanraj; Thompson, John M D; Mitchell, Edwin A; Murphy, Rinki; McCowan, Lesley M E; Shelling, Andrew N; On Behalf Of The Children Of Scope Study Group, G

2017-07-25

Childhood obesity is a public health problem, which is associated with a long-term increased risk of cardiovascular disease and premature mortality. Several gene variants have previously been identified that have provided novel insights into biological factors that contribute to the development of obesity. As obesity tracks through childhood into adulthood, identification of the genetic factors for obesity in early life is important. The objective of this study was to identify putative associations between genetic variants and obesity traits in children at 6 years of age. We recruited 1208 children of mothers from the New Zealand centre of the international Screening for Pregnancy Endpoints (SCOPE) study. Eighty common genetic variants associated with obesity traits were evaluated by the Sequenom assay. Body mass index standardised scores (BMI z-scores) and percentage body fat (PBF; measured by bio-impedance assay (BIA)) were used as anthropometric measures of obesity. A positive correlation was found between BMI z-scores and PBF (p obesity and obesity traits in New Zealand European children.

BMI or BIA: Is Body Mass Index or Body Fat Mass a Better Predictor of Cardiovascular Risk in Overweight or Obese Children and Adolescents? A German/Austrian/Swiss Multicenter APV Analysis of 3,327 Children and Adolescents.

Science.gov (United States)

Bohn, Barbara; Müller, Manfred James; Simic-Schleicher, Gunter; Kiess, Wieland; Siegfried, Wolfgang; Oelert, Monika; Tuschy, Sabine; Berghem, Stefan; Holl, Reinhard W

2015-01-01

Body fat (BF) percentiles for German children and adolescents have recently been published. This study aims to evaluate the association between bioelectrical impedance analysis (BIA)-derived BF and cardiovascular risk factors and to investigate whether BF is better suited than BMI in children and adolescents. Data of 3,327 children and adolescents (BMI > 90th percentile) were included. Spearman's correlation and receiver operating characteristics (ROCs) were applied determining the associations between BMI or BF and cardiovascular risk factors (hypertension, dyslipidemia, elevated liver enzymes, abnormal carbohydrate metabolism). Area under the curve (AUC) was calculated to predict cardiovascular risk factors. A significant association between both obesity indices and hypertension was present (all p risk factors. BF significantly predicted hypertension (AUC = 0.61), decreased HDL-cholesterol (AUC = 0.58), elevated LDL-cholesterol (AUC = 0.59), elevated liver enzymes (AUC = 0.61) (all p risk factors, no significant differences between BMI and BF were observed. BIA-derived BF was not superior to BMI to predict cardiovascular risk factors in overweight or obese children and adolescents.

Bioelectrical impedance analysis (BIA) for sarcopenic obesity (SO) diagnosis in young female subjects

International Nuclear Information System (INIS)

González-Correa, C H; Caicedo-Eraso, J C; Villada-Gomez J S

2013-01-01

Sarcopenia is defined as a loss of muscle mass depending of ageing and affecting physical function (definition A). A new definition considers excluding mass reduction criterion (definition B). Obesity is pandemic and occurs at all ages. Sarcopenic obesity (SO) implies both processes. The purpose of this study was to compare the results obtained after applying these 2 definitions in 66 aged 22 ± 2.8 years overweight or obese young college women. Percentage body fat (%BF) and skeletal mass index (SMI) were estimated by BIA, muscle function by handgrip strength test (HGS) and physical performance by Harvard step test (HST). There were 9.1% and 90.9% overweight or obese subjects. Twenty nine subjects (43.9%) had decreased HGS and 22 (33.3%) had impaired physical performance. One obese subject (1.5%) met the criteria for sarcopenic obesity by definition A and 9 (13.6%) by definition B. Although a linear regression (α 2 = 0.094, 0.037 and 0.275 respectively) it was observed a tendency for HGS, HST and SMI deterioration when %BF increases. However, other confounding factors must be investigated. Probably as the population gets more obese, the problematic of SO will be found earlier in life.

Silagem de colostro: caracterização do perfil de fermentação anaeróbia e desempenho de bezerros leiteiros

OpenAIRE

Lucas Silveira Ferreira

2011-01-01

O objetivo deste estudo foi caracterizar o perfil de fermentação anaeróbia de colostro e determinar seu valor nutritivo, assim como avaliar o desempenho de bezerros leiteiros alimentados com silagem de colostro como dieta líquida. No primeiro experimento, colostro bovino de segunda e terceira ordenhas foi fermentado em garrafas plásticas tipo PET que foram cheias e ligeiramente pressionadas antes do seu fechamento, criando assim uma condição anaeróbia. As garrafas foram armazenadas em sala es...

Body composition in dialysis patients: a functional assessment of bioimpedance using different prediction models.

Science.gov (United States)

Broers, Natascha J H; Martens, Remy J H; Cornelis, Tom; Diederen, Nanda M P; Wabel, Peter; van der Sande, Frank M; Leunissen, Karel M L; Kooman, Jeroen P

2015-03-01

The assessment of body composition (BC) in dialysis patients is of clinical importance given its role in the diagnosis of malnutrition and sarcopenia. Bioimpedance techniques routinely express BC as a 2-compartment (2-C) model distinguishing fat mass (FM) and fat-free mass (FFM), which may be influenced by the hydration of adipose tissue and fluid overload (OH). Recently, the BC monitor was introduced which applies a 3-compartment (3-C) model, distinguishing OH, adipose tissue mass, and lean tissue mass. The aim of this study was to compare BC between the 2-C and 3-C models and assess their relation with markers of functional performance (handgrip strength [HGS] and 4-m walking test), as well as with biochemical markers of nutrition. Forty-seven dialysis patients (30 males and 17 females) (35 hemodialysis, 12 peritoneal dialysis) with a mean age of 64.8 ± 16.5 years were studied. 3-C BC was assessed by BC monitor, whereas the obtained resistivity values were used to calculate FM and FFM according to the Xitron Hydra 4200 formulas, which are based on a 2-C model. FFM (3-C) was 0.99 kg (95% confidence interval [CI], 0.27 to 1.71, P = .008) higher than FFM (2-C). FM (3-C) was 2.43 kg (95% CI, 1.70-3.15, P FFM 3-C - FFM 2-C) (r = 0.361; P FFM (2-C) (r = 0.713; P FFM (3-C) (r = 0.711; P FFM (3-C) and FFM (2-C) were significantly related to HGS. Bioimpedance, HGS, and the 4-m walking test may all be valuable tools in the multidimensional nutritional assessment of both hemodialysis and peritoneal dialysis patients. Copyright © 2015 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Smartphone-Based Bioelectrical Impedance Analysis Devices for Daily Obesity Management

Directory of Open Access Journals (Sweden)

Ahyoung Choi

2015-09-01

Full Text Available Current bioelectric impedance analysis (BIA systems are often large, cumbersome devices which require strict electrode placement on the user, thus inhibiting mobile capabilities. In this work, we developed a handheld BIA device that measures impedance from multiple frequencies (5 kHz~200 kHz with four contact electrodes and evaluated the BIA device against standard body composition analysis systems: a dual-energy X-ray absorptiometry (DXA system (GE Lunar Prodigy, GE Healthcare, Buckinghamshire, UK and a whole-body BIA system (InBody S10, InBody, Co. Ltd, Seoul, Korea. In the study, 568 healthy participants, varying widely in body mass index, age, and gender, were recruited at two research centers: the Samsung Medical Center (SMC in South Korea and the Pennington Biomedical Research Center (PBRC in the United States. From the measured impedance data, we analyzed individual body fat and skeletal muscle mass by applying linear regression analysis against target reference data. Results indicated strong correlations of impedance measurements between the prototype pathways and corresponding InBody S10 electrical pathways (R = 0.93, p < 0.0001. Additionally, body fat estimates from DXA did not yield significant differences (p > 0.728 (paired t-test, DXA mean body fat 29.45 ± 10.77 kg, estimated body fat 29.52 ± 12.53 kg. Thus, this portable BIA system shows a promising ability to estimate an individual’s body composition that is comparable to large stationary BIA systems.

Evaluation of nutritional indicators and body composition in patients with advanced liver disease enrolled for liver transplantation.

Science.gov (United States)

Vulcano, Daniela Salate Biagioni; Carvalhaes, Maria Antonieta de Barros Leite; Bakonyi Neto, Alexandre

2013-10-01

Malnutrition is prevalent in patients with advanced liver disease (LD) related to multifactorial causes. Fluid retention can underestimate the nutritional status based on anthropometric measures. We evaluated nutritional indicators and body composition (BC) in patients with liver cirrhosis and correlated them with LD severity. Forty three patients with LD enrolled for liver transplantation were evaluated by Anthropometric measures, subjective evaluation (Global Assessment of Nutritional Status - SGA) and biochemical indicators. Single-frequency electrical bioimpedance (SFE-BIA) was used to evaluate body composition (BC). It measured resistance (R), reactance (Xc) and the phase angle (PA). LD severity was estimated by Child-Pugh and Meld criteria (Model for End-Stage Liver Disease). Child-Pugh index between patients was 7.11 ± 1.70 and Meld was 12.23 ± 4.22. Arm Circumference, Arm Muscle Circumference and Arm Muscle Area, SGA, hemoglobin, hematocrit and albumin showed better correlation with disease severity. Xc and PA showed correlation both with Meld and Child-Pugh score when BC were evaluated. PA was depleted in 55.8% of the patients. Diagnosis of malnutrition varied according to the method. Global assessment of nutritional status showed better correlation with disease severity than with objective methods. Single-frequency electrical bioimpedance for body composition analysis in cirrhotic patients must be cautiously used; however, primary vectors seems to be valid and promising in clinical practice.

25 CFR 10.11 - How would someone detained or incarcerated, or their representative, get the BIA policies and...

Science.gov (United States)

2010-04-01

... are used for operations or maintenance programs, the BIA's policies, standards, and procedures will be... physical or mental condition of the person at time of incarceration. In these cases, the Inmate Handbook...

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474

NARCIS (Netherlands)

van Esbroeck, Annelot C M; Janssen, Antonius P A; Cognetta, Armand B; Ogasawara, Daisuke; Shpak, Guy; van der Kroeg, Mark; Kantae, Vasudev; Baggelaar, Marc P; de Vrij, Femke M S; Deng, Hui; Allarà, Marco; Fezza, Filomena; Lin, Zhanmin; van der Wel, Tom; Soethoudt, Marjolein; Mock, Elliot D; den Dulk, Hans; Baak, Ilse L; Florea, Bogdan I; Hendriks, Giel; De Petrocellis, Luciano; Overkleeft, Herman S; Hankemeier, Thomas; De Zeeuw, Chris I; Di Marzo, Vincenzo; Maccarrone, Mauro; Cravatt, Benjamin F; Kushner, Steven A; van der Stelt, Mario

2017-01-01

A recent phase 1 trial of the fatty acid amide hydrolase (FAAH) inhibitor BIA 10-2474 led to the death of one volunteer and produced mild-to-severe neurological symptoms in four others. Although the cause of the clinical neurotoxicity is unknown, it has been postulated, given the clinical safety

25 CFR 161.713 - How will BIA determine the amount of damages to Navajo Partitioned Lands?

Science.gov (United States)

2010-04-01

... per month for comparable property or grazing privileges, or the estimated commercial value or replacement costs of the products or property. (c) BIA will determine the value of the products or property illegally used or removed based upon a valuation of similar products or property. ...

Does bioelectrical impedance analysis accurately estimate the condition of threatened and endangered desert fish species?

Science.gov (United States)

Dibble, Kimberly L.; Yard, Micheal D.; Ward, David L.; Yackulic, Charles B.

2017-01-01

Bioelectrical impedance analysis (BIA) is a nonlethal tool with which to estimate the physiological condition of animals that has potential value in research on endangered species. However, the effectiveness of BIA varies by species, the methodology continues to be refined, and incidental mortality rates are unknown. Under laboratory conditions we tested the value of using BIA in addition to morphological measurements such as total length and wet mass to estimate proximate composition (lipid, protein, ash, water, dry mass, energy density) in the endangered Humpback Chub Gila cypha and Bonytail G. elegans and the species of concern Roundtail Chub G. robusta and conducted separate trials to estimate the mortality rates of these sensitive species. Although Humpback and Roundtail Chub exhibited no or low mortality in response to taking BIA measurements versus handling for length and wet-mass measurements, Bonytails exhibited 14% and 47% mortality in the BIA and handling experiments, respectively, indicating that survival following stress is species specific. Derived BIA measurements were included in the best models for most proximate components; however, the added value of BIA as a predictor was marginal except in the absence of accurate wet-mass data. Bioelectrical impedance analysis improved the R2 of the best percentage-based models by no more than 4% relative to models based on morphology. Simulated field conditions indicated that BIA models became increasingly better than morphometric models at estimating proximate composition as the observation error around wet-mass measurements increased. However, since the overall proportion of variance explained by percentage-based models was low and BIA was mostly a redundant predictor, we caution against the use of BIA in field applications for these sensitive fish species.

Bioimpedance-based identification of malnutrition using fuzzy logic

International Nuclear Information System (INIS)

Wieskotten, S; Isermann, R; Heinke, S; Wabel, P; Moissl, U; Becker, J; Pirlich, M; Keymling, M

2008-01-01

Protein-energy malnutrition reduces the quality of life, lengthens the time in hospital and dramatically increases mortality. Currently there is no simple and objective method available for assessing nutritional status and identifying malnutrition. The aim of this work is to develop a novel assistance system that supports the physician in the assessment of the nutritional status. Therefore, three subject groups were investigated: the first group consisted of 688 healthy subjects. Two additional groups consisted of 707 patients: 94 patients with primary diseases that are known to cause malnutrition, and 613 patients from a hospital admission screening. In all subjects bioimpedance spectroscopy measurements were performed, and the body composition was calculated. Additionally, in all patients the nutritional status was assessed by the subjective global assessment score. These data are used for the development and validation of the assistance system. The basic idea of the system is that nutritional status is reflected by body composition. Hence, features of the nutritional status, based on the body composition, are determined and compared with reference ranges, derived from healthy subjects' data. The differences are evaluated by a fuzzy logic system or a decision tree in order to identify malnourished patients. The novel assistance system allows the identification of malnourished patients, and it can be applied for screening and monitoring of the nutritional status of hospital patients

Validation of bioelectrical-impedance analysis as a measurement of change in body composition in obesity

International Nuclear Information System (INIS)

Kushner, R.F.; Kunigk, A.; Alspaugh, M.; Andronis, P.T.; Leitch, C.A.; Schoeller, D.A.

1990-01-01

The bioelectrical-impedance-analysis (BIA) method accurately measures body composition in weight-stable subjects. This study validates the use of BIA to measure change in body composition. Twelve obese females underwent weight loss at a mean rate of 1.16 kg/wk. Body composition was measured by deuterium oxide dilution (D2O), BIA, and skinfold anthropometry (SFA) at baseline and at 5% decrements in weight. Highly significant correlations were obtained between D2O and BIA (r = 0.971) and between D2O and SFA (r = 0.932). Overall, BIA predicted change in fat-free mass with greater accuracy (to 0.4 kg) and precision (+/- 1.28 kg) than did anthropometry (to 0.8 kg and +/- 2.58 kg, respectively). We conclude that BIA is a useful clinical method for measuring change in body composition

A wireless, compact, and scalable bioimpedance measurement system for energy-efficient multichannel body sensor solutions

International Nuclear Information System (INIS)

Ramos, J; Ausín, J L; Lorido, A M; Redondo, F; Duque-Carrillo, J F

2013-01-01

In this paper, we present the design, realization and evaluation of a multichannel measurement system based on a cost-effective high-performance integrated circuit for electrical bioimpedance (EBI) measurements in the frequency range from 1 kHz to 1 MHz, and a low-cost commercially available radio frequency transceiver device, which provides reliable wireless communication. The resulting on-chip spectrometer provides high measuring EBI capabilities and constitutes the basic node to built EBI wireless sensor networks (EBI-WSNs). The proposed EBI-WSN behaves as a high-performance wireless multichannel EBI spectrometer where the number of nodes, i.e., number of channels, is completely scalable to satisfy specific requirements of body sensor networks. One of its main advantages is its versatility, since each EBI node is independently configurable and capable of working simultaneously. A prototype of the EBI node leads to a very small printed circuit board of approximately 8 cm 2 including chip-antenna, which can operate several years on one 3-V coin cell battery. A specifically tailored graphical user interface (GUI) for EBI-WSN has been also designed and implemented in order to configure the operation of EBI nodes and the network topology. EBI analysis parameters, e.g., single-frequency or spectroscopy, time interval, analysis by EBI events, frequency and amplitude ranges of the excitation current, etc., are defined by the GUI.

25 CFR 103.32 - What sort of loan documentation does BIA expect the lender to maintain?

Science.gov (United States)

2010-04-01

... other documentation of efforts to liquidate loan collateral; and (i) Originals or copies, as appropriate... 25 Indians 1 2010-04-01 2010-04-01 false What sort of loan documentation does BIA expect the... FINANCIAL ACTIVITIES LOAN GUARANTY, INSURANCE, AND INTEREST SUBSIDY Loan Servicing Requirements § 103.32...

[Sarcopenia: toward its clinical utilisation].

Science.gov (United States)

Bijlsma, Astrid Y; Meskers, Carel G M; Westendorp, Rudi G J; Maier, Andrea B

2013-01-01

Sarcopenia is a term that was introduced to describe 'low muscle mass'. There is no consensus definition for sarcopenia; a variety of criteria are being used to establish the diagnosis of 'sarcopenia'. Depending on the criteria used, the prevalence of sarcopenia in elderly varies from 7% to over 50%. The presence of sarcopenia often remains unrecognized when the loss of muscle mass is replaced by fat and connective tissue; body weight thus remains stable or even increases. Sarcopenia can be detected by measuring muscle mass with dual-energy X-ray absorptiometry (DEXA) or bioimpedance analysis (BIA). Besides the generation of strength, muscle tissue is an important internal organ involved in protein storage, glucose regulation, hormonal homeostasis and cellular communication. Systemic, cellular, neuromechanical factors and lifestyle are linked to the pathophysiology of sarcopenia. Sarcopenia is associated with higher mortality, dependency in activities of daily living, toxicity of chemotherapy, and disturbed glucose regulation.

A method for the estimation of hydration state during hemodialysis using a calf bioimpedance technique

International Nuclear Information System (INIS)

Zhu, F; Kuhlmann, M K; Kotanko, P; Seibert, E; Levin, N W; Leonard, E F

2008-01-01

Although many methods have been utilized to measure degrees of body hydration, and in particular to estimate normal hydration states (dry weight, DW) in hemodialysis (HD) patients, no accurate methods are currently available for clinical use. Biochemcial measurements are not sufficiently precise and vena cava diameter estimation is impractical. Several bioimpedance methods have been suggested to provide information to estimate clinical hydration and nutritional status, such as phase angle measurement and ratio of body fluid compartment volumes to body weight. In this study, we present a calf bioimpedance spectroscopy (cBIS) technique to monitor calf resistance and resistivity continuously during HD. Attainment of DW is defined by two criteria: (1) the primary criterion is flattening of the change in the resistance curve during dialysis so that at DW little further change is observed and (2) normalized resistivity is in the range of observation of healthy subjects. Twenty maintenance HD patients (12 M/8 F) were studied on 220 occasions. After three baseline (BL) measurements, with patients at their DW prescribed on clinical grounds (DW Clin ), the target post-dialysis weight was gradually decreased in the course of several treatments until the two dry weight criteria outlined above were met (DW cBIS ). Post-dialysis weight was reduced from 78.3 ± 28 to 77.1 ± 27 kg (p −2 Ω m 3 kg −1 (p cBIS was 0.3 ± 0.2%. The results indicate that cBIS utilizing a dynamic technique continuously during dialysis is an accurate and precise approach to specific end points for the estimation of body hydration status. Since no current techniques have been developed to detect DW as precisely, it is suggested as a standard to be evaluated clinically

Screening for sarcopenia in obesity

Science.gov (United States)

Sammarco, R.; Marra, M.; Montagnese, C.; De Rosa, E.; Onufrio, M.; Amato, V.; Santarpia, L.; De Caprio, C.; Contaldo, F.; Pasanisi, F.

2013-04-01

Sarcopenia is a progressive and generalized loss of skeletal muscle mass (SM) and function which can also be found in obese adults. The aim of the study was to evaluate the prevalence of sarcopenia in 1 245 obese women (18 - 67 years, weight 114.7±24.5 kg; BMI 44.1±9.2 fat mass 49.0±6.2%) from Southern Italy. Body composition was evaluated by bioimpedance analysis (BIA) and SM calculated by using Janssen's equation; therefore the sex-specific cut-off points of percentage skeletal muscle index were used. The whole population was divided in two age groups: A (18-40 years; n. 808; weight 115.4±23.5 kg; BMI 43.8±8.8 kg/m2) and B (41-67 years; n. 438; weight 113.4±26.3 kg; BMI 44.8±9.9 kg/m2). In all the sample there was 2.7% moderate and 0.6% severe sarcopenia; in group A, 1.9% moderate and 0.6% severe sarcopenia whilst in group B 4.3% moderate and 0.7% severe sarcopenia. The results of our study suggest that, based on a screening examination by BIA, moderate/severe sarcopenia can be detected in an unselected middle-aged obese population. Further studies are required to clarify the diagnosis with functional tests.

Screening for sarcopenia in obesity

International Nuclear Information System (INIS)

Sammarco, R; Marra, M; Montagnese, C; Rosa, E De; Onufrio, M; Amato, V; Santarpia, L; Caprio, C De; Contaldo, F; Pasanisi, F

2013-01-01

Sarcopenia is a progressive and generalized loss of skeletal muscle mass (SM) and function which can also be found in obese adults. The aim of the study was to evaluate the prevalence of sarcopenia in 1 245 obese women (18 – 67 years, weight 114.7±24.5 kg; BMI 44.1±9.2; fat mass 49.0±6.2%) from Southern Italy. Body composition was evaluated by bioimpedance analysis (BIA) and SM calculated by using Janssen's equation; therefore the sex-specific cut-off points of percentage skeletal muscle index were used. The whole population was divided in two age groups: A (18-40 years; n. 808; weight 115.4±23.5 kg; BMI 43.8±8.8 kg/m 2 ) and B (41-67 years; n. 438; weight 113.4±26.3 kg; BMI 44.8±9.9 kg/m 2 ). In all the sample there was 2.7% moderate and 0.6% severe sarcopenia; in group A, 1.9% moderate and 0.6% severe sarcopenia whilst in group B 4.3% moderate and 0.7% severe sarcopenia. The results of our study suggest that, based on a screening examination by BIA, moderate/severe sarcopenia can be detected in an unselected middle-aged obese population. Further studies are required to clarify the diagnosis with functional tests.

25 CFR 103.16 - How does BIA approve or reject a loan guaranty or insurance application?

Science.gov (United States)

2010-04-01

..., or if necessary, from liquidating loan collateral. Lenders are expected to obtain a first lien security interest in enough collateral to reasonably secure repayment of each loan guaranteed or insured... 25 Indians 1 2010-04-01 2010-04-01 false How does BIA approve or reject a loan guaranty or...

25 CFR 103.19 - When must the lender pay BIA the loan guaranty or insurance premium?

Science.gov (United States)

2010-04-01

... insurance premium? 103.19 Section 103.19 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES LOAN GUARANTY, INSURANCE, AND INTEREST SUBSIDY How a Lender Obtains a Loan Guaranty or Insurance Coverage § 103.19 When must the lender pay BIA the loan guaranty or insurance premium? The premium...

Body composition following stem cell transplant: comparison of bioimpedance and air-displacement plethysmography.

Science.gov (United States)

Hung, Yun-Chi; Bauer, Judith D; Horsely, Pamela; Ward, Leigh C; Bashford, John; Isenring, Elisabeth A

2014-09-01

The aim of this study was to assess the agreement between detected changes in body composition determined by bioimpedance spectroscopy (BIS) and air-displacement plethysmography (ADP) among patients with cancer undergoing peripheral blood stem cell transplantation (PBSCT); and to assess the agreement of absolute values of BIS with ADP and dual energy x-ray (DXA). Forty-four adult hematologic cancer patients undergoing PBSCT completed both BIS and ADP assessment at preadmission and at 3 mo after transplantation. A subsample (n = 11) was assessed by DXA at 3 mo after transplantation. Results were examined for the BIS instrument's default setting and three alternative predictive equations from the literature. Agreement was assessed by the Bland-Altman limits of agreement analysis while correlation was examined using the Lin's concordance correlation. Changes in body composition parameters assessed by BIS were comparable with those determined by ADP regardless of the predictive equations used. Bias of change in fat-free mass was clinically acceptable (all body mass index performed the best. Absolute body composition parameters predicted by the alternative predictive equations agreed with DXA and ADP better than the BIS instrument's default setting. Changes predicted by BIS were similar to those determined by ADP on a group level; however, agreement of predicted changes at an individual level should be interpreted with caution due to wide limits of agreement. Copyright © 2014 Elsevier Inc. All rights reserved.

Changes in body fluid and energy compartments during prolonged hunger strike.

Science.gov (United States)

Faintuch, J; Soriano, F G; Ladeira, J P; Janiszewski, M; Velasco, I T; Gama-Rodrigues, J J

2000-01-01

Prolonged total food deprivation in non-obese adults is rare, and few studies have documented body composition changes in this setting. In a group of eight hunger strikers who refused alimentation for 43 days, water and energy compartments were estimated, aiming to assess the impact of progressive starvation. Measurements included body mass index (BMI), triceps skinfold (TSF), arm muscle circumference (AMC), and bioimpedance (BIA) determinations of water, fat, lean body mass (LBM), and total resistance. Indirect calorimetry was also performed in one occasion. The age of the group was 43.3+/-6.2 years (seven males, one female). Only water, intermittent vitamins and electrolytes were ingested, and average weight loss reached 17.9%. On the last two days of the fast (43rd-44th day) rapid intravenous fluid, electrolyte, and vitamin replenishment were provided before proceeding with realimentation. Body fat decreased approximately 60% (BIA and TSF), whereas BMI reduced only 18%. Initial fat was estimated by BIA as 52.2+/-5.4% of body weight, and even on the 43rd day it was still measured as 19.7+/-3.8% of weight. TSF findings were much lower and commensurate with other anthropometric results. Water was comparatively low with high total resistance, and these findings rapidly reversed upon the intravenous rapid hydration. At the end of the starvation period, BMI (21.5+/-2.6 kg/m2) and most anthropometric determinations were still acceptable, suggesting efficient energy and muscle conservation. 1) All compartments diminished during fasting, but body fat was by far the most affected; 2) Total water was low and total body resistance comparatively elevated, but these findings rapidly reversed upon rehydration; 3) Exaggerated fat percentage estimates from BIA tests and simultaneous increase in lean body mass estimates suggested that this method was inappropriate for assessing energy compartments in the studied population; 4) Patients were not morphologically malnourished after

Changes in body fluid and energy compartments during prolonged hunger strike

Directory of Open Access Journals (Sweden)

Faintuch Joel

2000-01-01

Full Text Available Prolonged total food deprivation in non-obese adults is rare, and few studies have documented body composition changes in this setting. In a group of eight hunger strikers who refused alimentation for 43 days, water and energy compartments were estimated, aiming to assess the impact of progressive starvation. Measurements included body mass index (BMI, triceps skinfold (TSF, arm muscle circumference (AMC, and bioimpedance (BIA determinations of water, fat, lean body mass (LBM, and total resistance. Indirect calorimetry was also performed in one occasion. The age of the group was 43.3±6.2 years (seven males, one female. Only water, intermittent vitamins and electrolytes were ingested, and average weight loss reached 17.9%. On the last two days of the fast (43rd-44th day rapid intravenous fluid, electrolyte, and vitamin replenishment were provided before proceeding with realimentation. Body fat decreased approximately 60% (BIA and TSF, whereas BMI reduced only 18%. Initial fat was estimated by BIA as 52.2±5.4% of body weight, and even on the 43rd day it was still measured as 19.7±3.8% of weight. TSF findings were much lower and commensurate with other anthropometric results. Water was comparatively low with high total resistance, and these findings rapidly reversed upon the intravenous rapid hydration. At the end of the starvation period, BMI (21.5±2.6 kg/m² and most anthropometric determinations were still acceptable, suggesting efficient energy and muscle conservation. Conclusions: 1 All compartments diminished during fasting, but body fat was by far the most affected; 2 Total water was low and total body resistance comparatively elevated, but these findings rapidly reversed upon rehydration; 3 Exaggerated fat percentage estimates from BIA tests and simultaneous increase in lean body mass estimates suggested that this method was inappropriate for assessing energy compartments in the studied population; 4 Patients were not morphologically

PREFACE: XV International Conference on Electrical Bio-Impedance (ICEBI) & XIV Conference on Electrical Impedance Tomography (EIT)

Science.gov (United States)

Pliquett, Uwe

2013-04-01

Over recent years advanced measurement methods have facilitated outstanding achievements not only in medical instrumentation but also in biotechnology. Impedance measurement is a simple and innocuous way to characterize materials. For more than 40 years biological materials, most of them based on cells, have been characterized by means of electrical impedance for quality control of agricultural products, monitoring of biotechnological or food processes or in health care. Although the list of possible applications is long, very few applications successfully entered the market before the turn of the century. This was, on the one hand, due to the low specificity of electrical impedance with respect to other material properties because it is influenced by multiple factors. On the other hand, equipment and methods for many potential applications were not available. With the appearance of microcontrollers that could be easily integrated in applications at the beginning of the 1980s, impedance measurement advanced as a valuable tool in process optimization and lab automation. However, established methods and data processing were mostly used in a new environment. This has changed significantly during the last 10 years with a dramatic growth of the market for medical instrumentation and also for biotechnological applications. Today, advanced process monitoring and control require fast and highly parallel electrical characterization which in turn yields incredible data volumes that must be handled in real time. Many newer developments require miniaturized but precise sensing methods which is one of the main parts of Lab-on-Chip technology. Moreover, biosensors increasingly use impedometric transducers, which are not compatible with the large expensive measurement devices that are common in the laboratory environment. Following the achievements in the field of bioimpedance measurement, we will now witness a dramatic development of new electrode structures and electronics

Wearable Vector Electrical Bioimpedance System to Assess Knee Joint Health.

Science.gov (United States)

Hersek, Sinan; Toreyin, Hakan; Teague, Caitlin N; Millard-Stafford, Mindy L; Jeong, Hyeon-Ki; Bavare, Miheer M; Wolkoff, Paul; Sawka, Michael N; Inan, Omer T

2017-10-01

We designed and validated a portable electrical bioimpedance (EBI) system to quantify knee joint health. Five separate experiments were performed to demonstrate the: 1) ability of the EBI system to assess knee injury and recovery; 2) interday variability of knee EBI measurements; 3) sensitivity of the system to small changes in interstitial fluid volume; 4) reducing the error of EBI measurements using acceleration signals; and 5) use of the system with dry electrodes integrated to a wearable knee wrap. 1) The absolute difference in resistance ( R) and reactance (X) from the left to the right knee was able to distinguish injured and healthy knees (p knee R was 2.5 Ω and for X was 1.2 Ω. 3) Local heating/cooling resulted in a significant decrease/increase in knee R (p knee R and X measured using the wet electrodes and the designed wearable knee wrap were highly correlated ( R 2 = 0.8 and 0.9, respectively). This study demonstrates the use of wearable EBI measurements in monitoring knee joint health. The proposed wearable system has the potential for assessing knee joint health outside the clinic/lab and help guide rehabilitation.

Survey of Forest Elephants Loxodonta cyclotis (Matschie, 1900 (Mammalia: Proboscidea: Elephantidae in the Bia Conservation Area, Ghana

Directory of Open Access Journals (Sweden)

Emmanuel Danquah

2014-10-01

Full Text Available Information on elephant ranges and numbers is vital for effective conservation and management, especially in western Africa where elephant populations are small and scattered.  The Bia Conservation Area (BCA in southwestern Ghana is a priority site for the conservation of Forest Elephants in western Africa.  A dung count was conducted using a systematic segmented track line design to determine the density and distribution of the BCA elephant population.  The mean density of dung-piles was 452.15 per sq.km. and mean dung survival time was estimated to be 54.64 days (SD 2 days, leading to an estimate of 146 elephants (95% confidence interval 98-172 with a density of 0.48/km2 for the BCA. This estimate probably makes the Bia forest elephant population the largest in Ghana.  Records of BCA elephant activities were also made.  This study augments the Regional African Elephant Database and should facilitate strategic planning and management programmes.

Business English in the Eyes of Economics and Management Students at the University of Białystok

Directory of Open Access Journals (Sweden)

Dzięcioł-Pędich Agnieszka

2014-09-01

Full Text Available According to the regulations of the Polish Ministry of Science and Higher Education, university graduates should have to know a foreign language at B2 level, as described in The Common European Framework of Reference, and they should know its specialized variety. These are the only recommendations concerning general language courses and their specialized varieties. It is up to schools of foreign languages or other institutions providing language courses for institutions of higher education to determine requirements concerning language for specific purposes. However, students are rarely asked to contribute to the development of curricula and syllabi. This article presents the results of a survey conducted among students of Economics and Management at the University of Białystok. The survey was devoted to students’ perceptions of Business English in English courses conducted by the School of Foreign Languages at the University of Białystok. The aim of the survey was to answer the following questions:

Is it possible and necessary to control European spruce bark beetle Ips typographus (L. outbreak in the Białowieża Forest?

Directory of Open Access Journals (Sweden)

Hilszczański Jacek

2017-03-01

Full Text Available In response to the information published in ‘Forest Research Papers’ (vol. 77(4, 2016, regarding the problem of the European spruce bark beetle Ips typographus (L. in the Białowieża Forest, we present our viewpoint on this issue. The role of the European spruce bark beetle in the Białowieża Forest is discussed based on the experience gained in Europe’s forests. We present the effects of I. typographus outbreaks on forest biodiversity as well as outbreak mitigation in the context of the processes taking place in semi-natural forests.

Improvement of nutritional status as assessed by multifrequency BIA during 15 weeks of refeeding in adolescent girls with anorexia nervosa.

Science.gov (United States)

Mika, Claudia; Herpertz-Dahlmann, Beate; Heer, Martina; Holtkamp, Kristian

2004-11-01

In patients with anorexia nervosa (AN), an assessment of changes in body composition and nutritional status is crucial for adequate nutritional management during refeeding therapies. Phase-sensitive multifrequency bioelectrical impedance analysis (BIA) is an inexpensive and noninvasive technique with which to determine nutritional status and body composition. We investigated 21 female adolescents with AN (initial BMI 15.5 +/- 1.1 kg/m(2)) 4 times between wk 3 and 15 of inpatient refeeding and 19 normal-weight, age-matched female controls. From wk 3 to 15, BMI, fat mass, body cell mass (BCM), total body water (TBW), intracellular water (ICW) but not extracellular mass (ECM), and extracellular water (ECW) increased significantly. Reactance (Xc), phase angle (PhA), and the ECM/BCM index as parameters of nutritional status improved significantly in patients and no longer differed from controls in wk 15, although the BMI of patients was significantly lower than those of controls. Changes in the ECM/BCM index were due to accretion of BCM, which was associated with an increase of ICW. Multifrequency phase-sensitive BIA seems to be a promising tool for the assessment of changes in nutritional status and body composition in patients with AN. An individually determined and controlled hyperenergetic diet as part of a multidimensional, interdisciplinary treatment program for eating disorders seems to quickly improve the nutritional status of AN patients.

Hand-to-Hand Model for Bioelectrical Impedance Analysis to Estimate Fat Free Mass in a Healthy Population

Directory of Open Access Journals (Sweden)

Hsueh-Kuan Lu

2016-10-01

Full Text Available This study aimed to establish a hand-to-hand (HH model for bioelectrical impedance analysis (BIA fat free mass (FFM estimation by comparing with a standing position hand-to-foot (HF BIA model and dual energy X-ray absorptiometry (DXA; we also verified the reliability of the newly developed model. A total of 704 healthy Chinese individuals (403 men and 301 women participated. FFM (FFMDXA reference variables were measured using DXA and segmental BIA. Further, regression analysis, Bland–Altman plots, and cross-validation (2/3 participants as the modeling group, 1/3 as the validation group; three turns were repeated for validation grouping were conducted to compare tests of agreement with FFMDXA reference variables. In male participants, the hand-to-hand BIA model estimation equation was calculated as follows: FFMmHH = 0.537 h2/ZHH − 0.126 year + 0.217 weight + 18.235 (r2 = 0.919, standard estimate of error (SEE = 2.164 kg, n = 269. The mean validated correlation coefficients and limits of agreement (LOAs of the Bland–Altman analysis of the calculated values for FFMmHH and FFMDXA were 0.958 and −4.369–4.343 kg, respectively, for hand-to-foot BIA model measurements for men; the FFM (FFMmHF and FFMDXA were 0.958 and −4.356–4.375 kg, respectively. The hand-to-hand BIA model estimating equation for female participants was FFMFHH = 0.615 h2/ZHH − 0.144 year + 0.132 weight + 16.507 (r2 = 0.870, SEE = 1.884 kg, n = 201; the three mean validated correlation coefficient and LOA for the hand-to-foot BIA model measurements for female participants (FFMFHH and FFMDXA were 0.929 and −3.880–3.886 kg, respectively. The FFMHF and FFMDXA were 0.942 and −3.511–3.489 kg, respectively. The results of both hand-to-hand and hand-to-foot BIA models demonstrated similar reliability, and the hand-to-hand BIA models are practical for assessing FFM.

Hand-to-Hand Model for Bioelectrical Impedance Analysis to Estimate Fat Free Mass in a Healthy Population.

Science.gov (United States)

Lu, Hsueh-Kuan; Chiang, Li-Ming; Chen, Yu-Yawn; Chuang, Chih-Lin; Chen, Kuen-Tsann; Dwyer, Gregory B; Hsu, Ying-Lin; Chen, Chun-Hao; Hsieh, Kuen-Chang

2016-10-21

This study aimed to establish a hand-to-hand (HH) model for bioelectrical impedance analysis (BIA) fat free mass (FFM) estimation by comparing with a standing position hand-to-foot (HF) BIA model and dual energy X-ray absorptiometry (DXA); we also verified the reliability of the newly developed model. A total of 704 healthy Chinese individuals (403 men and 301 women) participated. FFM (FFM DXA ) reference variables were measured using DXA and segmental BIA. Further, regression analysis, Bland-Altman plots, and cross-validation (2/3 participants as the modeling group, 1/3 as the validation group; three turns were repeated for validation grouping) were conducted to compare tests of agreement with FFM DXA reference variables. In male participants, the hand-to-hand BIA model estimation equation was calculated as follows: FFM m HH = 0.537 h²/Z HH - 0.126 year + 0.217 weight + 18.235 ( r ² = 0.919, standard estimate of error (SEE) = 2.164 kg, n = 269). The mean validated correlation coefficients and limits of agreement (LOAs) of the Bland-Altman analysis of the calculated values for FFM m HH and FFM DXA were 0.958 and -4.369-4.343 kg, respectively, for hand-to-foot BIA model measurements for men; the FFM (FFM m HF ) and FFM DXA were 0.958 and -4.356-4.375 kg, respectively. The hand-to-hand BIA model estimating equation for female participants was FFM F HH = 0.615 h²/Z HH - 0.144 year + 0.132 weight + 16.507 ( r ² = 0.870, SEE = 1.884 kg, n = 201); the three mean validated correlation coefficient and LOA for the hand-to-foot BIA model measurements for female participants (FFM F HH and FFM DXA ) were 0.929 and -3.880-3.886 kg, respectively. The FFM HF and FFM DXA were 0.942 and -3.511-3.489 kg, respectively. The results of both hand-to-hand and hand-to-foot BIA models demonstrated similar reliability, and the hand-to-hand BIA models are practical for assessing FFM.

The association of body composition parameters with nonalcoholic hepatic steatosis

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Mesut Sipahi

2015-06-01

Full Text Available Objective:Nonalcoholic fatty liver disease (NAFLD which is strongly correlated with obesity; has been a common worldwide health problem with the improvements in social status. Body composition studies are accepted as a simple follow-up tool for treatment of obesity. Since the correlation of body mass index (BMI with the hepatosteatosis (HS is well known; the aim of this study was to assess the usefulness of body composition parameters (BCP to determine HS on NAFLD patients; using dual bioimpedance analyzer (BIA. Methods:A total of 253 patients with diagnosis of NAFLD were included into the study. The demographic parameters such as age, sex and BMI were collected; and the ultrasonographic (US evolution was performed to determine the HS stages. The BCP, such as amount and the percentage of total body fat, fat free mass, and total body water were assessed with the dual bioimpedance analyzer. Results:There were strong significant correlations between BMI and HS, between BCP and HS (p0.05. Conclusion: According to our results, it can be concluded that BCP values may have a diagnostic value on diagnosis of NAFLD.

Textrode-enabled transthoracic electrical bioimpedance measurements - towards wearable applications of impedance cardiography

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Juan Carlos Márquez Ruiz

2013-10-01

Full Text Available During the last decades the use of Electrical Bioimpedance (EBI in the medical field has been subject of extensive research, especially since it is an affordable, harmless and non-invasive technology. In some specific applications such as body composition assessment where EBI has proven a good degree of effectiveness and reliability, the use of textile electrodes and measurement garments have shown a good performance and reproducible results. Impedance Cardiography (ICG is another modality of EBI that can benefit from the implementation and use of wearable sensors. ICG technique is based on continuous impedance measurements of a longitudinal segment across the thorax taken at a single frequency. The need for specific electrode placement on the thorax and neck can be easily ensured with the use of a garment with embedded textile electrodes, textrodes. The first step towards the implementation of ICG technology into a garment is to find out if ICG measurements with textile sensors give a good enough quality of the signal to allow the estimation of the fundamental ICG parameters. In this work, the measurement performance of a 2-belt set with incorporated textrodes for thorax and neck was compared against ICG measurements obtained with Ag/AgCl electrodes. The analysis was based on the quality of the fundamental ICG signals (∆Z, dZ/dt and ECG, systolic time intervals and other ICG parameters. The obtained results indicate the feasibility of using textrodes for ICG measurements with consistent measurements and relatively low data dispersion. Thus, enabling the development of measuring garments for ICG measurements.

The use of bioelectrical impedance analysis for body composition in epidemiological studies

DEFF Research Database (Denmark)

Böhm, A; Heitmann, B L

2013-01-01

BACKGROUND/OBJECTIVES: Bioelectrical impedance analysis (BIA) is a relatively simple, inexpensive and non-invasive technique to measure body composition and is therefore suitable in field studies and larger surveys. SUBJECTS/METHODS: We performed an overview of BIA-derived body fat percentages (BF......%) from 55 published studies of healthy populations aged 6-80 years. In addition, the relationship between body mass index (BMI) and body composition is documented in the context of BIA as a good alternative to closely differentiate which composition of the body better relates to the risk...

V-dotO2max prediction from multi-frequency bioelectrical impedance analysis

International Nuclear Information System (INIS)

Stahn, Alexander; Strobel, Günther; Terblanche, Elmarie

2008-01-01

Bioelectrical impedance analysis (BIA) has been shown to be highly related to skeletal muscle mass and blood volume, both of which are important determinants of maximal oxygen uptake (V-dotO 2max ). The aim of the present study was therefore to investigate the ability of whole-body and segmental multi-frequency BIA to improve current nonexercise V-dotO 2max prediction models. Data for V-dotO 2max (mL min −1 ), anthropometry, self-reported physical activity (PA-R) and BIA were collected in 115 men and women. Multiple linear regression analysis (MLR) was used to develop the most parsimonious prediction model. Segmental BIA was not superior to whole-body measurements. Correlation coefficients between V-dotO 2max and resistance indices were significantly higher at 500 kHz compared to 50 kHz (p 2max (r = 0.89). After adjusting for age, gender and PA-R, MLR revealed that the inclusion of intracellular resistance index was slightly, but significantly (p 2max ( −1 ). In short, whole-body BIA marginally improves the accuracy of nonexercise V-dotO 2max prediction models and its advantage is most pronounced in individuals with particularly low V-dotO 2max

Body Composition Assessment and Nutritional Status Evaluation in Men and Women Portuguese Centenarians.

Science.gov (United States)

Pereira da Silva, A; Matos, A; Valente, A; Gil, Â; Alonso, I; Ribeiro, R; Bicho, M; Gorjão-Clara, J

2016-03-01

in women (W = 71.85% vs. M = 28.15%), 95% of men revealed criteria for osteoporosis. Resting metabolic rate (RMR) was significantly different between genders using bioimpedance analysis (W= 1123.33± 173.91; M= 1350.10± 188.88; prelation to nutritional status, centenarians were more frequently underweight than overweight. The thinness could be a natural process, contributing for the longevity being rather overweight a reducing factor in life expectancy. BMI and waist circumference showed a good correlation with body fat percentage. Despite the results of Bland- Altman analysis, Deurenberg and Gallagher equations are not suitable to evaluate obesity prevalence in centenarians. Harris Benedict equation seems to be a good option to measure RMR in centenaries, when BIA is not available. Body composition and nutritional characterization of Portuguese centenarians are relevant contribution in scientific evidence production for the action plan of healthy ageing in Europe (2012-2020) and also for clinical practice.

25 CFR 115.601 - Under what circumstances may the BIA restrict your IIM account through supervision or an...

Science.gov (United States)

2010-04-01

... property, including your financial affairs;” or (3) Determines through an administrative process that you... professional that you are “incapable of managing or administering property, including your financial affairs... IIM funds as security/collateral for the transaction; (ii) A copy of the document showing that the BIA...

25 CFR 171.500 - How does BIA determine the annual operation and maintenance assessment rate for the irrigation...

Science.gov (United States)

2010-04-01

... costs needed for the reliable operation of the irrigation facility infrastructure; (8) Maintenance of a... 25 Indians 1 2010-04-01 2010-04-01 false How does BIA determine the annual operation and... Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER IRRIGATION OPERATION AND...

Hydration measurement by bioimpedance spectroscopy and blood pressure management in children on hemodialysis.

Science.gov (United States)

Zaloszyc, Ariane; Schaefer, Betti; Schaefer, Franz; Krid, Saoussen; Salomon, Rémi; Niaudet, Patrick; Schmitt, Claus Peter; Fischbach, Michel

2013-11-01

Hypertension is frequent in chronic hemodialyzed patients and usually treated by reducing extracellular fluid. Probing dry weight only based on a clinical evaluation may be hazardous, especially in case of volume independent hypertension. We performed a 1-year retrospective study in three pediatric centers to define the relation between blood pressure (BP) and hydration status, assessed by whole-body bioimpedance spectroscopy (BIS). We analyzed 463 concomitant measurements of BP, relative overhydration (rel.OH), and plasma sodium (Napl) in 23 children (mean age 13.9 ± 5.1 years). Pre-dialytic under-hydration (rel.OH  +15%) was assessed, however, the majority (73%) showed normal BP. Patient-specific Napl setpoint could not be described. Mean dialysate sodium concentration was higher than mean Napl. Hypertension is not always related to overhydration. Therefore, BIS should restrict the practice of "probing dry weight" in hypertensive children. Moreover, sodium dialytic balance needs to be considered to improve BP management.

Ventilation and Heart Rate Monitoring in Drivers using a Contactless Electrical Bioimpedance System

Science.gov (United States)

Macías, R.; García, M. A.; Ramos, J.; Bragós, R.; Fernández, M.

2013-04-01

Nowadays, the road safety is one of the most important priorities in the automotive industry. Many times, this safety is jeopardized because of driving under inappropriate states, e.g. drowsiness, drugs and/or alcohol. Therefore several systems for monitoring the behavior of subjects during driving are researched. In this paper, a device based on a contactless electrical bioimpedance system is shown. Using the four-wire technique, this system is capable of obtaining the heart rate and the ventilation of the driver through multiple textile electrodes. These textile electrodes are placed on the car seat and the steering wheel. Moreover, it is also reported several measurements done in a controlled environment, i.e. a test room where there are no artifacts due to the car vibrations or the road state. In the mentioned measurements, the system response can be observed depending on several parameters such as the placement of the electrodes or the number of clothing layers worn by the driver.

Ventilation and Heart Rate Monitoring in Drivers using a Contactless Electrical Bioimpedance System

International Nuclear Information System (INIS)

Macías, R; García, M A; Ramos, J; Bragós, R; Fernández, M

2013-01-01

Nowadays, the road safety is one of the most important priorities in the automotive industry. Many times, this safety is jeopardized because of driving under inappropriate states, e.g. drowsiness, drugs and/or alcohol. Therefore several systems for monitoring the behavior of subjects during driving are researched. In this paper, a device based on a contactless electrical bioimpedance system is shown. Using the four-wire technique, this system is capable of obtaining the heart rate and the ventilation of the driver through multiple textile electrodes. These textile electrodes are placed on the car seat and the steering wheel. Moreover, it is also reported several measurements done in a controlled environment, i.e. a test room where there are no artifacts due to the car vibrations or the road state. In the mentioned measurements, the system response can be observed depending on several parameters such as the placement of the electrodes or the number of clothing layers worn by the driver.

A wireless multi-channel bioimpedance measurement system for personalized healthcare and lifestyle.

Science.gov (United States)

Ramos, Javier; Ausín, José Luis; Lorido, Antonio Manuel; Redondo, Francisco; Duque-Carrillo, Juan Francisco

2013-01-01

Miniaturized, noninvasive, wearable sensors constitute a fundamental prerequisite for pervasive, predictive, and preventive healthcare systems. In this sense, this paper presents the design, realization, and evaluation of a wireless multi-channel measurement system based on a cost-effective high-performance integrated circuit for electrical bioimpedance (EBI) measurements in the frequency range from 1 kHz to 1 MHz. The resulting on-chip spectrometer provides high measuring EBI capabilities and together with a low-cost, commercially available radio frequency transceiver device. It provides reliable wireless communication, constitutes the basic node to build EBI wireless sensor networks (EBI-WSNs). The proposed EBI-WSN behaves as a high-performance wireless multi-channel EBI spectrometer, where the number of channels is completely scalable and independently configurable to satisfy specific measurement requirements of each individual. A prototype of the EBI node leads to a very small printed circuit board of approximately 8 cm2 including chip-antenna, which can operate several years on one 3-V coin cell battery and make it suitable for long-term preventive healthcare monitoring.

Numerical expression of volume status using the bioimpedance ratio in continuous ambulatory peritoneal dialysis patients: A pilot study

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Mun Jang

2017-09-01

Full Text Available Background: Volume overload results in higher mortality rates in patients on continuous ambulatory peritoneal dialysis (CAPD. The ratio of bioimpedance (RBI might be a helpful parameter in adjusting dry body weight in CAPD patients. This study examined whether it is possible to distinguish between non-hypervolemic status and hypervolemic status in CAPD patients by using only RBI. Methods: RBI was calculated as follows: RBI = impedance at 50 kHz/impedance at 500 kHz. Based on the experts’ judgements, a total of 64 CAPD patients were divided into two groups, a non-hypervolemic group and a hypervolemic group. The RBI was measured from right wrist to right ankle (rw-raRBI by bioimpedance spectroscopy (BCM®, Fresenius Medical Care before and after the peritosol was emptied. Other RBIs were measured from the right side of the anterior superior iliac spine to the ipsilateral ankle (rasis-raRBI to control for the electro-physiological effects of peritoneal dialysate. Results: The mean rw-raRBI of non-hypervolemic patients was higher than that of hypervolemic patients in the presence (1.141 ± 0.022 vs. 1.121 ± 0.021, P < 0.001 of a peritosol. Likewise, the mean rasis-raRBI of non-hypervolemic patients was higher than that of hypervolemic patients (presence of peritosol: 1.136 ± 0.026 vs. 1.109 ± 0.022, P < 0.001; absence of peritosol: 1.131 ± 0.022 vs. 1.107 ± 0.022, P < 0.001. Conclusion: The volume status of CAPD patients was able to be simply expressed by RBI. Therefore, this study suggests that when patients cannot be analyzed using BCM, RBI could be an alternative.

Validity of bioelectrical impedance analysis in estimation of fat-free mass in colorectal cancer patients.

Science.gov (United States)

Ræder, Hanna; Kværner, Ane Sørlie; Henriksen, Christine; Florholmen, Geir; Henriksen, Hege Berg; Bøhn, Siv Kjølsrud; Paur, Ingvild; Smeland, Sigbjørn; Blomhoff, Rune

2018-02-01

Bioelectrical impedance analysis (BIA) is an accessible and cheap method to measure fat-free mass (FFM). However, BIA estimates are subject to uncertainty in patient populations with altered body composition and hydration. The aim of the current study was to validate a whole-body and a segmental BIA device against dual-energy X-ray absorptiometry (DXA) in colorectal cancer (CRC) patients, and to investigate the ability of different empiric equations for BIA to predict DXA FFM (FFM DXA ). Forty-three non-metastatic CRC patients (aged 50-80 years) were enrolled in this study. Whole-body and segmental BIA FFM estimates (FFM whole-bodyBIA , FFM segmentalBIA ) were calculated using 14 empiric equations, including the equations from the manufacturers, before comparison to FFM DXA estimates. Strong linear relationships were observed between FFM BIA and FFM DXA estimates for all equations (R 2  = 0.94-0.98 for both devices). However, there were large discrepancies in FFM estimates depending on the equations used with mean differences in the ranges -6.5-6.8 kg and -11.0-3.4 kg for whole-body and segmental BIA, respectively. For whole-body BIA, 77% of BIA derived FFM estimates were significantly different from FFM DXA , whereas for segmental BIA, 85% were significantly different. For whole-body BIA, the Schols* equation gave the highest agreement with FFM DXA with mean difference ±SD of -0.16 ± 1.94 kg (p = 0.582). The manufacturer's equation gave a small overestimation of FFM with 1.46 ± 2.16 kg (p FFM DXA (0.17 ± 1.83 kg (p = 0.546)). Using the manufacturer's equation, no difference in FFM estimates was observed (-0.34 ± 2.06 kg (p = 0.292)), however, a clear proportional bias was detected (r = 0.69, p FFM compared to DXA using the optimal equation. In a population of non-metastatic CRC patients, mostly consisting of Caucasian adults and with a wide range of body composition measures, both the whole-body BIA and segmental BIA device

Accuracy of Bioelectrical Impedance Analysis in Estimated Longitudinal Fat-Free Mass Changes in Male Army Cadets.

Science.gov (United States)

Langer, Raquel D; Matias, Catarina N; Borges, Juliano H; Cirolini, Vagner X; Páscoa, Mauro A; Guerra-Júnior, Gil; Gonçalves, Ezequiel M

2018-03-26

Bioelectrical impedance analysis (BIA) is a practical and rapid method for making a longitudinal analysis of changes in body composition. However, most BIA validation studies have been performed in a clinical population and only at one moment, or point in time (cross-sectional study). The aim of this study is to investigate the accuracy of predictive equations based on BIA with regard to the changes in fat-free mass (FFM) in Brazilian male army cadets after 7 mo of military training. The values used were determined using dual-energy X-ray absorptiometry (DXA) as a reference method. The study included 310 male Brazilian Army cadets (aged 17-24 yr). FFM was measured using eight general predictive BIA equations, with one equation specifically applied to this population sample, and the values were compared with results obtained using DXA. The student's t-test, adjusted coefficient of determination (R2), standard error of estimation (SEE), Lin's approach, and the Bland-Altman test were used to determine the accuracy of the predictive BIA equations used to estimate FFM in this population and between the two moments (pre- and post-moment). The FFM measured using the nine predictive BIA equations, and determined using DXA at the post-moment, showed a significant increase when compared with the pre-moment (p FFM changes in the army cadets between the two moments in a very similar way to the reference method (DXA). However, only the one BIA equation specific to this population showed no significant differences in the FFM estimation between DXA at pre- and post-moment of military routine. All predictive BIA equations showed large limits of agreement using the Bland-Altman approach. The eight general predictive BIA equations used in this study were not found to be valid for analyzing the FFM changes in the Brazilian male army cadets, after a period of approximately 7 mo of military training. Although the BIA equation specific to this population is dependent on the amount of

25 CFR 166.819 - What happens if the BIA does not collect enough money to satisfy the penalty?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What happens if the BIA does not collect enough money to... does not collect enough money to satisfy the penalty? We will send written notice to the trespasser demanding immediate settlement and advising the trespasser that unless settlement is received within five...

Deuterium oxide dilution and body composition in overweight and obese schoolchildren aged 6-9 years

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Wendell Costa Bila

2016-02-01

Full Text Available ABSTRACT OBJECTIVE: To correlate different methods of body composition assessment in overweight or obese schoolchildren, using deuterium oxide (D2O dilution as a reference. METHODS: Percentage of total body water (%TBW, fat free mass (%FFM, and body fat (%BF were assessed by D2O and tetrapolar electrical bioimpedance analysis (BIA in 54 obese and overweight students aged 6-9 years. Skinfold thickness (ST, body mass index (BMI, conicity index (CI, waist circumference (WC, waist-to-height ratio (WHtR, and waist-to-hip (WHR ratio were also used. RESULTS: Mean values for body composition were 38.4% ± 8.4% BF, 44.9% ± 6.1% TBW and 61.6% ± 8.4% FFM. There was no significant difference in body weight, body fat mass (FM, TBW, and FFM between genders. Regarding D2O, ST underestimated %BF, and overestimated %FFM in both genders (p < 0.05. BIA overestimated %TBW in the group as a whole and in males (p < 0.05. The only positive and strong correlations occurred in females regarding the WC (s= 0.679, CI (r = 0.634, and WHtR (r = 0.666. CONCLUSIONS: In this sample of obese and overweight children, there were strong correlations between body composition measured by D2O and some indices and anthropometric indicators in females, but there was no positive and strong correlation of fat tissue with the indices/indicators at all ages and in both genders.

Prediction of fat-free mass by bioelectrical impedance analysis in older adults from developing countries: a cross-validation study using the deuterium dilution method

International Nuclear Information System (INIS)

Mateo, H. Aleman; Romero, J. Esparza; Valencia, M.E.

2010-01-01

Objective: Several limitations of published bioelectrical impedance analysis (BIA) equations have been reported. The aims were to develop in a multiethnic, elderly population a new prediction equation and cross- validate it along with some published BIA equations for estimating fat-free mass using deuterium oxide dilution as the reference method. Design and setting: Cross-sectional study of elderly from five developing countries. Methods: Total body water (TBW) measured by deuterium dilution was used to determine fat-free mass (FFM) in 383 subjects. Anthropometric and BIA variables were also measured. Only 377 subjects were included for the analysis, randomly divided into development and cross-validation groups after stratified by gender. Stepwise model selection was used to generate the model and Bland Altman analysis was used to test agreement. Results: FFM = 2.95 - 3.89 (Gender) + 0.514 (Ht2/Z) + 0.090 (Waist) + 0.156 (Body weight). The model fit parameters were an R2, total F-Ratio, and the SEE of 0.88, 314.3, and 3.3, respectively. None of the published BIA equations met the criteria for agreement. The new BIA equation underestimated FFM by just 0.3 kg in the cross-validation sample. The mean of the difference between FFM by TBW and the new BIA equation were not significantly different; 95% of the differences were between the limits of agreement of -6.3 to 6.9 kg of FFM. There was no significant association between the mean of the differences and their averages (r= 0.008 and p= 0.2). Conclusions:This new BIA equation offers a valid option compared with some of the current published BIA equations to estimate FFM in elderly subjects from five developing countries. (Authors)

Phase sensitive spectral domain interferometry for label free biomolecular interaction analysis and biosensing applications

Science.gov (United States)

Chirvi, Sajal

Biomolecular interaction analysis (BIA) plays vital role in wide variety of fields, which include biomedical research, pharmaceutical industry, medical diagnostics, and biotechnology industry. Study and quantification of interactions between natural biomolecules (proteins, enzymes, DNA) and artificially synthesized molecules (drugs) is routinely done using various labeled and label-free BIA techniques. Labeled BIA (Chemiluminescence, Fluorescence, Radioactive) techniques suffer from steric hindrance of labels on interaction site, difficulty of attaching labels to molecules, higher cost and time of assay development. Label free techniques with real time detection capabilities have demonstrated advantages over traditional labeled techniques. The gold standard for label free BIA is surface Plasmon resonance (SPR) that detects and quantifies the changes in refractive index of the ligand-analyte complex molecule with high sensitivity. Although SPR is a highly sensitive BIA technique, it requires custom-made sensor chips and is not well suited for highly multiplexed BIA required in high throughput applications. Moreover implementation of SPR on various biosensing platforms is limited. In this research work spectral domain phase sensitive interferometry (SD-PSI) has been developed for label-free BIA and biosensing applications to address limitations of SPR and other label free techniques. One distinct advantage of SD-PSI compared to other label-free techniques is that it does not require use of custom fabricated biosensor substrates. Laboratory grade, off-the-shelf glass or plastic substrates of suitable thickness with proper surface functionalization are used as biosensor chips. SD-PSI is tested on four separate BIA and biosensing platforms, which include multi-well plate, flow cell, fiber probe with integrated optics and fiber tip biosensor. Sensitivity of 33 ng/ml for anti-IgG is achieved using multi-well platform. Principle of coherence multiplexing for multi

Białoruskie elementy językowe w rosyjskiej gwarze staroobrzędowców mieszkających w regionie suwalsko-augustowskim

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Dorota Angelika Paśko-Koneczniak

2014-12-01

Full Text Available Elements of the Belarusian language in the Russian dialect used by the Old Believers living in the Suwałki-Augustów region The article deals with the Belarusian elements in the Russian dialect of the Old Believers living in Poland. The Old Believers arrived in Poland in the second half of the 18th century. At present they live in the Suwałki-Augustów region in the north-eastern Poland. They inhabit mostly two villages in the county of Suwałki, namely Gabowe Grądy and Bór, which are very close to each other, and three towns: Augustów, Suwałki and Sejny. The dialect used by the Polish Old Believers represents the western Central Great Russian dialects characterized by akanie, the so-called Pskov group. They share features which are typical of Pskov. The dialect was also influenced by other north-eastern Belarusian dialects, that is, the ones which were closest to the areas originally inhabited by Old Believers, who migrated in phases. After each phase, their dialect came to reflect some new linguistic influences. A large number of lexemes directly borrowed from Polish, or via the Belarusian language, are found in this dialect, which is also characterized by other features common in Belarusian dialects or the Bulgarian language. By way of illustration, they include the following features: the prosthetic j-, prosthetic v-, the occurrence of the endings –im and –ym in the case of singular masculine adjectives in the locative, promotion of the endings –i and –y in the case of the plural masculine and neutral nouns in the nominative, and the occurrence of lexemes borrowed from the Belarusian language.   Białoruskie elementy językowe w rosyjskiej gwarze staroobrzędowców mieszkających w regionie suwalsko-augustowskim Artykuł poświęcony jest problematyce białoruskich elementów językowych w rosyjskiej gwarze staroobrzędowców mieszkających w Polsce. Staroobrzędowcy pojawili się na terytorium Polski w drugiej połowie XVIII

Positive phase error from parallel conductance in tetrapolar bio-impedance measurements and its compensation

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Ivan M Roitt

2010-01-01

Full Text Available Bioimpedance measurements are of great use and can provide considerable insight into biological processes.  However, there are a number of possible sources of measurement error that must be considered.  The most dominant source of error is found in bipolar measurements where electrode polarisation effects are superimposed on the true impedance of the sample.  Even with the tetrapolar approach that is commonly used to circumvent this issue, other errors can persist. Here we characterise the positive phase and rise in impedance magnitude with frequency that can result from the presence of any parallel conductive pathways in the measurement set-up.  It is shown that fitting experimental data to an equivalent electrical circuit model allows for accurate determination of the true sample impedance as validated through finite element modelling (FEM of the measurement chamber.  Finally, the model is used to extract dispersion information from cell cultures to characterise their growth.

A FPGA-Based Broadband EIT System for Complex Bioimpedance Measurements—Design and Performance Estimation

Directory of Open Access Journals (Sweden)

Roman Kusche

2015-07-01

Full Text Available Electrical impedance tomography (EIT is an imaging method that is able to estimate the electrical conductivity distribution of living tissue. This work presents a field programmable gate array (FPGA-based multi-frequency EIT system for complex, time-resolved bioimpedance measurements. The system has the capability to work with measurement setups with up to 16 current electrodes and 16 voltage electrodes. The excitation current has a range of about 10 µA to 5 mA, whereas the sinusoidal signal used for excitation can have a frequency of up to 500 kHz. Additionally, the usage of a chirp or rectangular signal excitation is possible. Furthermore, the described system has a sample rate of up to 3480 impedance spectra per second (ISPS. The performance of the EIT system is demonstrated with a resistor-based phantom and tank phantoms. Additionally, first measurements taken from the human thorax during a breathing cycle are presented.

Nova proposta de teste incremental de remada na avaliação aeróbia de surfistas

Directory of Open Access Journals (Sweden)

Felipe Bercht CANOZZI

2015-09-01

Full Text Available ResumoOs objetivos desse estudo foram: 1 verificar as respostas do lactato sanguíneo e da frequência cardíaca (FC durante um protocolo de campo específico de remada no surfe; 2 correlacionar os índices de capacidade e potência aeróbia determinados nesse protocolo específico com o tempo de prática da modalidade e variáveis antropométricas. Participaram deste estudo nove sujeitos (24 ± 4,5 anos; 72,2 ± 6,7 kg; 178,4 ± 4,8 cm que foram submetidos a um teste progressivo intermitente de remada sobre a sua própria prancha de surfe, do tipo vai e vêm, com velocidades iniciais entre 1-1,1 m/s e incrementos de 0,05 m/s a cada 3 min até a exaustão voluntária. Uma resposta linear e exponencial foram observadas para a FC e o lactato sanguíneo, respectivamente, durante o protocolo incremental. Este comportamento foi semelhante ao demonstrado durante protocolos incrementais com objetivo de avaliar a capacidade e a potência aeróbia realizados em outras modalidades cíclicas. Além disso, foram encontradas correlações significantes entre o pico de velocidade (PV e a velocidade correspondente ao início do acúmulo de lactato no sangue (vOBLA (r = 0,87, p = 0,005 e do PV com tempo de prática de surfe (r = 0,70, p = 0,03. No entanto, não foram encontradas correlações significativas entre PV e vOBLA com nenhuma das variáveis antropométricas mensuradas. Assim, podemos concluir que o protocolo incremental específico de remada no surfe utilizado no presente estudo poderia ser uma ferramenta útil na determinação de índices relacionados à capacidade (vOBLA e potência (PV aeróbia de surfistas.

An implantable bioimpedance monitor using 2.45 GHz band for telemetry

International Nuclear Information System (INIS)

Bogónez-Franco, Paco; Nescolarde, Lexa; Bragós, Ramon; Rosell-Ferrer, Javier; Gálvez-Montón, Carolina

2013-01-01

This paper describes a multi-frequency single-channel electrical implantable bioimpedance monitor (35 mm × 35 mm × 10 mm, weight 52 g) powered by a NiMH battery. By using the tetrapolar method and injecting 10 µA peak , the monitor is capable of measuring at 14 different frequencies, from 100 Hz to 200 kHz. It contains a ZigBee transceiver to monitor the measurements performed, and has an embedded memory for backing up the data. RC networks and in-situ heart excised tissues were used to test the system. When measuring a full spectrum every 5 min, 35 days of autonomy are possible due to the low power consumption of the monitor. Temperature drift was estimated by short-term and long-term measurements. Temperature cycling was used to measure modulus and phase angle stability. The result was a very low effect on a modulus decrease of 2.34 Ω, with respect to an impedance of 322 Ω, at 100 Hz and a phase angle increase of 1.1°, at 200 kHz. In addition, measurement errors were bigger at low frequencies because of the high impedance of the electrodes used, which was higher than 10 kΩ at frequencies below 1 kHz. (paper)

Comparison of Dual Energy X-ray Absorptiometry and Bioimpedance in Assessing Body Composition and Nutrition in Peritoneal Dialysis Patients

DEFF Research Database (Denmark)

Popovic, Velena; Zerahn, Bo; Heaf, James Goya

2017-01-01

OBJECTIVE: Peritoneal dialysis (PD) patients are characterized by protein malnutrition and muscle wasting. Reliable, easy, and cheap methods for evaluating nutrition are desirable. Three methods are commonly available: dual-energy X-ray absorptiometry (DXA), bioimpedance (BI), and subjective global...... assessment (SGA).The objective of the study was to compare the previously mentioned methods for assessment of body composition and nutritional status in PD patients. DESIGN: The study is cross-sectional and consisted of 72 PD patients from a single center PD ambulatorium. METHODS: Participants were measured...... in this population. OH might reduce DXA accuracy in PD patients. LTI and ICW may be useful measures to supplement SGA in assessing nutrition....

Towards the development of a wearable Electrical Impedance Tomography system: A study about the suitability of a low power bioimpedance front-end.

Science.gov (United States)

Menolotto, Matteo; Rossi, Stefano; Dario, Paolo; Della Torre, Luigi

2015-01-01

Wearable systems for remote monitoring of physiological parameter are ready to evolve towards wearable imaging systems. The Electrical Impedance Tomography (EIT) allows the non-invasive investigation of the internal body structure. The characteristics of this low-resolution and low-cost technique match perfectly with the concept of a wearable imaging device. On the other hand low power consumption, which is a mandatory requirement for wearable systems, is not usually discussed for standard EIT applications. In this work a previously developed low power architecture for a wearable bioimpedance sensor is applied to EIT acquisition and reconstruction, to evaluate the impact on the image of the limited signal to noise ratio (SNR), caused by low power design. Some anatomical models of the chest, with increasing geometric complexity, were developed, in order to evaluate and calibrate, through simulations, the parameters of the reconstruction algorithms provided by Electrical Impedance Diffuse Optical Reconstruction Software (EIDORS) project. The simulation results were compared with experimental measurements taken with our bioimpedance device on a phantom reproducing chest tissues properties. The comparison was both qualitative and quantitative through the application of suitable figures of merit; in this way the impact of the noise of the low power front-end on the image quality was assessed. The comparison between simulation and measurement results demonstrated that, despite the limited SNR, the device is accurate enough to be used for the development of an EIT based imaging wearable system.

Effect of psychological stress on gastric motility assessed by electrical bio-impedance.

Science.gov (United States)

Huerta-Franco, María Raquel; Vargas-Luna, Miguel; Montes-Frausto, Juana Berenice; Morales-Mata, Ismael; Ramirez-Padilla, Lorena

2012-09-28

To evaluate gastric motility using electrical bio-impedance (EBI) and gastric changes as a result of stress induced by psychological tests. A group of 57 healthy women, aged 40-60 years, was recruited, and a clinical history and physical examination were performed. The women were free from severe anxiety, chronic or acute stress, severe depression, mental diseases and conditions that affect gastric activity. The women were evaluated under fasting conditions, and using a four-electrode configuration, the gastric signals were obtained through a BIOPAC MP-150 system. The volunteers were evaluated using the following paradigm: basal state, recording during the Stroop Test, intermediate resting period, recording during the Raven Test, and a final resting period. We analyzed the relative areas of the frequency spectrum: A1 (1-2 cpm), A2 (2-4 cpm), A3 (4-8 cpm), and A4 (8-12 cpm), as well as the median of area A2 + A3. The data were analyzed by an autoregressive method using a Butterworth filter with MatLab and Origin. Analysis of variance (ANOVA) and Friedman ANOVA (for nonparametric variables) were performed; in addition, pairs of groups were compared using the T dependent and Wilcoxon T tests. The results of the main values of area A2 were not significantly different comparing the five steps of the experimental paradigm. Nevertheless, there was a tendency of this A2 region to decrease during the stress tests, with recuperation at the final resting step. When an extended gastric region was considered (1-4 cpm), significant differences with the psychological stress tests were present (F = 3.85, P = 0.005). The A3 region also showed significant changes when the stress psychological tests were administered (F = 7.25, P stress test showed significant changes (F = 5.5, P stress test (P stress can be evaluated by short-term EBI.

Fat-free mass prediction equations for bioelectric impedance analysis compared to dual energy X-ray absorptiometry in obese adolescents: a validation study

NARCIS (Netherlands)

Hofsteenge, G.H.; Chin A Paw, M.J.M.; Weijs, P.J.M.

2015-01-01

Background: In clinical practice, patient friendly methods to assess body composition in obese adolescents are needed. Therefore, the bioelectrical impedance analysis (BIA) related fat-free mass (FFM) prediction equations (FFM-BIA) were evaluated in obese adolescents (age 11-18 years) compared to

25 CFR 166.814 - How will the BIA determine the value of the products or property illegally used or removed?

Science.gov (United States)

2010-04-01

... the BIA determine the value of the products or property illegally used or removed? We will determine the value of the products or property illegally used or removed based upon a valuation of similar... property illegally used or removed? 166.814 Section 166.814 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF...

„Silę ucho”, czyli co słychać w przekładzie. Niemieckojęzyczne warianty wiersza Skakanka ufoistki Mirona Białoszewskiego na tle zabiegów „przekładania” codzienności na język poetycki

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Aleksandra Burba

2014-01-01

Full Text Available The article has been derived from a chapter of an MA thesis on everyday speech in Miron Białoszewski’s work. The text focuses on exposition of methodological assumptions - the notion of everyday speech and its translation into poetic language in Białoszewski’s works. In particular, the article discusses a series of non-professional translations of the poem UFO agent’s skipping rope into German, as an example of the functioning of the dominant of everyday speech in translations of Białoszewski’s poetry.

The tourism potential of the commune Janów Podlaski and its evaluation of tourism appeal as compared to the administrative district of Biała Podlaska (Lublin voivodeship)

Science.gov (United States)

Skrzypczak, Andrzej; Chmielewska, Anna Beata

2009-01-01

The purpose of this thesis has been to evaluate tourism appeal of the commune of Janów Podlaski, as compared to the other communes in the administrative district of Biała Podlaska, and to analyse the recreational potential of the natural environment within the commune and it's present day infrastructure for tourism industry. For evaluation of the tourism attractiveness of the commune, based on comparative analysis, the method of synthetic measures was applied. The commune of Janów Podlaski belongs to one of the most attractive areas for tourists in the administrative district of Biała Podlaska. The attractiveness of the commune is associated with the Bug river, which flows across high-value landscapes and possess many ecological assets. Development of water tourism, however, is hindered by the fact that the Bug forms part of Poland's state border and it's water is rather polluted. Walking tourism in the commune of Janów Podlaski is encouraged owing to a well-developed and properly sing-posted networks of trails. The accommodation facilities are not evenly distributed as most of the rooms for tourists can be found in Janów Podlaski.

Cisovka - the relic population of Abies alba and its relationship to man-made silver-fir stands in Białowieża primeval forest

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Leon Mejnartowicz

2014-01-01

Full Text Available In Białowieża Primeval Forest, in 1823 Stanisław Górski discovered on the Cisovka Hag, a relic population of European silver-fir (Abies alba Mill.. This population is isolated and most away, 120 km to the North-East, from the border of European-silver-fir distribution. Besides the natural population Cisovka, there are also man-made silver fir stands and clumps in the Polish and Belorussian part of Białowieża Primeval Forest. In the Polish part there are four such artificial stands. If the seed-producing silver-fir stands really originated from the Cisovka population, then they are a very valuable part of the declining population and an easy accessible seed source. However, if these populations were introduced to the Białowieża Primeval Forest, then they are a potential source of dangerous genetic pollution of the Cisovka population. The relationship of the genetic structure of the Cisovka population to man-made silver-fir-stands in Białowieża Forest was investigated with the help of 17 loci of 1 1 enzyme systems. Genetic diversity of Cisovka population is characterized by the smallest mean number of alleles per locus (Mal= 1.353, includes all loci studied and per polimorphic locus Malp = 2.00. In Cisovka population there is very low-grade of polimorphic loci (Pp = 11.765 with the mean 37.255 for all studied populations. Expected heterozygosity, He = 0.079 revealed very low-grade of genetic diversity in the population. The observed heterozygosity (Ho = 0.123 was similar to this characterictic in other populations. A dendrogram based on Neis genetic distance coefficient (D among 9 silver-fir populations was constructed. Cisovka in the UPGMA dendrogram is a distinct population separated from other ones by a very great genetic distance (D = 0.06. Also two man-made silver-fir (B I and 132 stands are separated from others. Only populations B3 and B4 are combined into one subgroup linked to the population Tomaszów Lubelski. Basing on the

Baltic Sea coastal erosion; a case study from the Jastrzębia Góra region

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Uścinowicz Grzegorz

2014-12-01

Full Text Available The coastline in the Jastrzębia Góra area can be divided into three major zones of general importance: a beach and barrier section, a cliff section, and a section protected by a heavy hydrotechnical construction. These areas are characterised by a diverse geology and origin, and hence different vulnerability to erosion. In addition, observations have demonstrated a different pace of erosion within each zone. Based on the results obtained by remote sensing methods (analysis of aerial photographs and maps, it has been determined that the coastline in the barrier area, i.e., to the west of Jastrzębia Góra, moved landwards by about 130 m, in a period of 100 years, and 80 m over about 50 years. A smaller displacement of the shoreline could be observed within the cliff. Between the middle of the twentieth and the start of the twenty-first centuries the shore retreated by about 25 m. However, in recent years, an active landslide has led to the displacement of the uppermost part of the cliff locally up to 25 m. Another issue is, functioning since 2000, a heavy hydrotechnical construction which has been built in order to protect the most active part of the cliff. The construction is not stable and its western part, over a distance of 50 m, has moved almost 2 m vertically downwards and c. 2.5 m horizontally towards the sea in the past two years. This illustrates that the erosional factor does not comprise only marine abrasion, but also involves land-based processes determined by geology and hydrogeology. Changes in the shoreline at the beach and barrier part are constantly conditioned by rising sea levels, the slightly sloping profile of the sea floor and low elevation values of the backshore and dune areas. Cliffs are destroyed by mass wasting and repetitive storm surges that are responsible for the removal of the colluvium which protects the coast from adverse wave effects. Presumably, mass movements combined with groundwater outflow from the cliff

Experimental validation of a method for removing the capacitive leakage artifact from electrical bioimpedance spectroscopy measurements

International Nuclear Information System (INIS)

Buendia, R; Seoane, F; Gil-Pita, R

2010-01-01

Often when performing electrical bioimpedance (EBI) spectroscopy measurements, the obtained EBI data present a hook-like deviation, which is most noticeable at high frequencies in the impedance plane. The deviation is due to a capacitive leakage effect caused by the presence of stray capacitances. In addition to the data deviation being remarkably noticeable at high frequencies in the phase and the reactance spectra, the measured EBI is also altered in the resistance and the modulus. If this EBI data deviation is not properly removed, it interferes with subsequent data analysis processes, especially with Cole model-based analyses. In other words, to perform any accurate analysis of the EBI spectroscopy data, the hook deviation must be properly removed. Td compensation is a method used to compensate the hook deviation present in EBI data; it consists of multiplying the obtained spectrum, Z meas (ω), by a complex exponential in the form of exp(–jωTd). Although the method is well known and accepted, Td compensation cannot entirely correct the hook-like deviation; moreover, it lacks solid scientific grounds. In this work, the Td compensation method is revisited, and it is shown that it should not be used to correct the effect of a capacitive leakage; furthermore, a more developed approach for correcting the hook deviation caused by the capacitive leakage is proposed. The method includes a novel correcting expression and a process for selecting the proper values of expressions that are complex and frequency dependent. The correctness of the novel method is validated with the experimental data obtained from measurements from three different EBI applications. The obtained results confirm the sufficiency and feasibility of the correcting method

[Guidelines for budget impact analysis of health technologies in Brazil].

Science.gov (United States)

Ferreira-Da-Silva, Andre Luis; Ribeiro, Rodrigo Antonini; Santos, Vânia Cristina Canuto; Elias, Flávia Tavares Silva; d'Oliveira, Alexandre Lemgruber Portugal; Polanczyk, Carisi Anne

2012-07-01

Budget impact analysis (BIA) provides operational financial forecasts to implement new technologies in healthcare systems. There were no previous specific recommendations to conduct such analyses in Brazil. This paper reviews BIA methods for health technologies and proposes BIA guidelines for the public and private Brazilian healthcare system. The following recommendations were made: adopt the budget administrator's perspective; use a timeframe of 1 to 5 years; compare reference and alternative scenarios; consider the technology's rate of incorporation; estimate the target population by either an epidemiological approach or measured demand; consider restrictions on technologies' indication or factors that increase the demand for them; consider direct and averted costs; do not adjust for inflation or discounts; preferably, integrate information on a spreadsheet; calculate the incremental budget impact between scenarios; and summarize information in a budget impact report.

Comparação da produção de biogás a partir da digestão anaeróbia de diferentes tipos de lodo

OpenAIRE

Jayna Pessuto Silva; Daniele Perondi; Danielle Restelatto; Marcelo Godinho; Aline Dettmer

2016-01-01

Neste trabalho foi avaliada a produção de biogás a partir da digestão anaeróbia (DA) de resíduos de arroz (utilizado para cultivo de fungos) e couro curtido ao cromo (RCCC) (inóculos). Adicionaram-se a estes, lodos de estação de tratamento de efluentes, provenientes de um curtume (LC) e de uma universidade (LU). A digestão anaeróbia gera biogás, rico em metano, e pode ser uma alternativa para o tratamento de resíduos. O objetivo deste estudo foi avaliar o volume e a fração molar do biogás ger...

Budget impact analysis-principles of good practice: report of the ISPOR 2012 Budget Impact Analysis Good Practice II Task Force.

Science.gov (United States)

Sullivan, Sean D; Mauskopf, Josephine A; Augustovski, Federico; Jaime Caro, J; Lee, Karen M; Minchin, Mark; Orlewska, Ewa; Penna, Pete; Rodriguez Barrios, Jose-Manuel; Shau, Wen-Yi

2014-01-01

, disease severity mix, or treatment patterns cannot be credibly captured by using the cost calculator approach, a cohort or patient-level condition-specific model may be used to estimate the budget impact of the new intervention, accounting appropriately for those entering and leaving the eligible population over time. In either case, the BIA should use data that reflect values specific to a particular decision maker's population. Sensitivity analysis should be of alternative scenarios chosen from the perspective of the decision maker. The validation of the model should include at least face validity with decision makers and verification of the calculations. Data sources for the BIA should include published clinical trial estimates and comparator studies for the efficacy and safety of the current and new interventions as well as the decision maker's own population for the other parameter estimates, where possible. Other data sources include the use of published data, well-recognized local or national statistical information, and, in special circumstances, expert opinion. Reporting of the BIA should provide detailed information about the input parameter values and calculations at a level of detail that would allow another modeler to replicate the analysis. The outcomes of the BIA should be presented in the format of interest to health care decision makers. In a computer program, options should be provided for different categories of costs to be included or excluded from the analysis. We recommend a framework for the BIA, provide guidance on the acquisition and use of data, and offer a common reporting format that will promote standardization and transparency. Adherence to these good research practice principles would not necessarily supersede jurisdiction-specific BIA guidelines but may support and enhance local recommendations or serve as a starting point for payers wishing to promulgate methodology guidelines. © 2013 International Society for Pharmacoeconomics and

BMI or BIA: Is Body Mass Index or Body Fat Mass a Better Predictor of Cardiovascular Risk in Overweight or Obese Children and Adolescents?

Science.gov (United States)

Bohn, Barbara; Müller, Manfred James; Simic-Schleicher, Gunter; Kiess, Wieland; Siegfried, Wolfgang; Oelert, Monika; Tuschy, Sabine; Berghem, Stefan; Holl, Reinhard W.

2015-01-01

Background Body fat (BF) percentiles for German children and adolescents have recently been published. This study aims to evaluate the association between bioelectrical impedance analysis(BIA)-derived BF and cardiovascular risk factors and to investigate whether BF is better suited than BMI in children and adolescents. Methods Data of 3,327 children and adolescents (BMI > 90th percentile) were included. Spearman's correlation and receiver operating characteristics (ROCs) were applied determining the associations between BMI or BF and cardiovascular risk factors (hypertension, dyslipidemia, elevated liver enzymes, abnormal carbohydrate metabolism). Area under the curve (AUC) was calculated to predict cardiovascular risk factors. Results A significant association between both obesity indices and hypertension was present (all p correlation with BMI was stronger (r = 0.22) compared to BF (r = 0.13). There were no differences between BMI and BF regarding their correlation with other cardiovascular risk factors. BF significantly predicted hypertension (AUC = 0.61), decreased HDL-cholesterol (AUC = 0.58), elevated LDL-cholesterol (AUC = 0.59), elevated liver enzymes (AUC = 0.61) (all p < 0.0001), and elevated triglycerides (AUC = 0.57, p < 0.05), but not abnormal carbohydrate metabolism (AUC = 0.54, p = 0.15). For the prediction of cardiovascular risk factors, no significant differences between BMI and BF were observed. Conclusion BIA-derived BF was not superior to BMI to predict cardiovascular risk factors in overweight or obese children and adolescents. PMID:26087841

Hydration in advanced cancer: can bioelectrical impedance analysis improve the evidence base? A systematic review of the literature.

Science.gov (United States)

Nwosu, Amara Callistus; Mayland, Catriona R; Mason, Stephen R; Khodabukus, Andrew F; Varro, Andrea; Ellershaw, John E

2013-09-01

Decisions surrounding the administration of clinically assisted hydration to patients dying of cancer can be challenging because of the limited understanding of hydration in advanced cancer and a lack of evidence to guide health care professionals. Bioelectrical impedance analysis (BIA) has been used to assess hydration in various patient groupings, but evidence for its use in advanced cancer is limited. To critically appraise existing methods of hydration status assessment in advanced cancer and review the potential for BIA to assess hydration in advanced cancer. Searches were carried out in four electronic databases. A hand search of selected peer-reviewed journals and conference abstracts also was conducted. Studies reporting (de)hydration assessment (physical examination, biochemical measures, symptom assessment, and BIA) in patients with advanced cancer were included. The results highlight how clinical examination and biochemical tests are standard methods of assessing hydration, but limitations exist with these methods in advanced cancer. Furthermore, there is disagreement over the evidence for some commonly associated symptoms with dehydration in cancer. Although there are limitations with using BIA alone to assess hydration in advanced cancer, analysis of BIA raw measurements through the method of bioelectrical impedance vector analysis may have a role in this population. The benefits and burdens of providing clinically assisted hydration to patients dying of cancer are unclear. Bioelectrical impedance vector analysis shows promise as a hydration assessment tool but requires further study in advanced cancer. Innovative methodologies for research are required to add to the evidence base and ultimately improve the care for the dying. Copyright © 2013 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.

A comparative study of PCA, SIMCA and Cole model for classification of bioimpedance spectroscopy measurements.

Science.gov (United States)

Nejadgholi, Isar; Bolic, Miodrag

2015-08-01

Due to safety and low cost of bioimpedance spectroscopy (BIS), classification of BIS can be potentially a preferred way of detecting changes in living tissues. However, for longitudinal datasets linear classifiers fail to classify conventional Cole parameters extracted from BIS measurements because of their high variability. In some applications, linear classification based on Principal Component Analysis (PCA) has shown more accurate results. Yet, these methods have not been established for BIS classification, since PCA features have neither been investigated in combination with other classifiers nor have been compared to conventional Cole features in benchmark classification tasks. In this work, PCA and Cole features are compared in three synthesized benchmark classification tasks which are expected to be detected by BIS. These three tasks are classification of before and after geometry change, relative composition change and blood perfusion in a cylindrical organ. Our results show that in all tasks the features extracted by PCA are more discriminant than Cole parameters. Moreover, a pilot study was done on a longitudinal arm BIS dataset including eight subjects and three arm positions. The goal of the study was to compare different methods in arm position classification which includes all three synthesized changes mentioned above. Our comparative study on various classification methods shows that the best classification accuracy is obtained when PCA features are classified by a K-Nearest Neighbors (KNN) classifier. The results of this work suggest that PCA+KNN is a promising method to be considered for classification of BIS datasets that deal with subject and time variability. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Effect of an Acute After-School Exercise Bout on Percentage of Body Fat Using Leg-to-Leg Bioelectrical Impedance Analysis in Children

Science.gov (United States)

Andreacci, Joseph L.; Dixon, Curt B.; Rompolski, Krista; VanGorden, Kelly M.

2008-01-01

Bioelectrical impedance analysis (BIA) is a fast, easy to administer, and relatively inexpensive method of evaluating body composition. Due to the ease of operation, interest in using BIA to estimate percentage of body fat (%BF) has grown, especially in settings where body composition assessments are often performed without the benefit of…

A temporal-omic study of Propionibacterium freudenreichii CIRM-BIA1 adaptation strategies in conditions mimicking cheese ripening in the cold.

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Marion Dalmasso

Full Text Available Propionibacterium freudenreichii is used as a ripening culture in Swiss cheese manufacture. It grows when cheeses are ripened in a warm room (about 24°C. Cheeses with an acceptable eye formation level are transferred to a cold room (about 4°C, inducing a marked slowdown of propionic fermentation, but P. freudenreichii remains active in the cold. To investigate the P. freudenreichii strategies of adaptation and survival in the cold, we performed the first global gene expression profile for this species. The time-course transcriptomic response of P. freudenreichii CIRM-BIA1(T strain was analyzed at five times of incubation, during growth at 30°C then for 9 days at 4°C, under conditions preventing nutrient starvation. Gene expression was also confirmed by RT-qPCR for 28 genes. In addition, proteomic experiments were carried out and the main metabolites were quantified. Microarray analysis revealed that 565 genes (25% of the protein-coding sequences of P. freudenreichii genome were differentially expressed during transition from 30°C to 4°C (P1. At 4°C, a general slowing down was observed for genes implicated in the cell machinery. On the contrary, P. freudenreichii CIRM-BIA1(T strain over-expressed genes involved in lactate, alanine and serine conversion to pyruvate, in gluconeogenesis, and in glycogen synthesis. Interestingly, the expression of different genes involved in the formation of important cheese flavor compounds, remained unchanged at 4°C. This could explain the contribution of P. freudenreichii to cheese ripening even in the cold. In conclusion, P. freudenreichii remains metabolically active at 4°C and induces pathways to maintain its long-term survival.

Correlation between ultrafiltration rate and phase angle measured by BIA in chronic kidney disease patients on regular hemodialysis

Science.gov (United States)

Nasution, B. R.; Lubis, A. R.

2018-03-01

Chronic Kidney Disease (CKD) patients with regular hemodialysis have high rates of morbidity and mortality that may be related to the hemodynamic effects of rapid UFR and low PhA value. In this study, we investigated whether high UFR is associated with a low value of PhA thus indirectly affect the risk of morbidity and mortality. UFR and Bioelectrical Impedance Analysis (BIA) examination on 92 subjects were recorded shortly after HD and analyzed by using Pearson correlation test. Multivariate analysis was also conducted to identify several factors that can affect the value of Phase angle. The number of HD regular CKD patients with PhA<4 based on the division of the UFR (cc/kg/h) <10, 10-13, ≥ 13, respectively were3, 10 and 6, whereas patients with ≥ 4 PhA <10, 10-13, ≥ 13respectively were 60, 11, and 2. The results showed a significant relationship between UFR with PhA. In CKD patients with regular HD, UFR has aninverse relationship with the value of PhA. After multivariate analysis, the UFR and the etiology of HD are still significantly affect the value of PhA. UFR optimal value in patients with CKD with regular HD is <10 cc/kg/h.

The additional value of bioelectrical impedance analysis-derived muscle mass as a screening tool in geriatric assessment for fall prevention.

Science.gov (United States)

Van Puyenbroeck, Karolien; Roelandts, Lieven; Van Deun, Thomas; Van Royen, Paul; Verhoeven, Veronique

2012-01-01

The decline in skeletal muscle in old age is a factor in the development of functional limitations. The objective of this study was to assess if there is a correlation between muscle mass based on bioelectrical impedance analysis (BIA) detection and the fall incidence in nursing home residents and to examine the risk factors for falling in nursing home residents. This prospective cohort study was part of a longitudinal study on nutritional issues in 52 nursing homes in Antwerp (Belgium) from October 2007 to April 2008. Two hundred and seventy-six people aged 65 years and older were included. Each subject was assessed with BIA, the timed get-up-and-go test, the Katz score, the Mini Nutritional Assessment - Short Form and the 36-Item Short Form Health Survey. The primary outcome parameter was fall incidence during the study. The prevalence of sarcopenia varied from 24.3 to 81.5% depending on which definition was used. No association was found between BIA-derived muscle mass and fall incidence. Logistic regression analysis showed that gait speed (odds ratio 1.029; p = 0.003) and mental health (odds ratio 0.981; p = 0.015) are significantly associated with fall incidence in nursing homes. A receiver operating characteristic curve showed that none of the BIA-derived muscle parameters are good predictors of the risk of falling. This study shows that there is no association between sarcopenia based on BIA and fall incidence and that BIA-derived muscle mass has no additional value in predicting fall incidents compared to the timed get-up-and-go test. Copyright © 2012 S. Karger AG, Basel.

Development of bioelectrical impedance analysis-based equations for estimation of body composition in postpartum rural Bangladeshi women.

Science.gov (United States)

Shaikh, Saijuddin; Schulze, Kerry J; Kurpad, Anura; Ali, Hasmot; Shamim, Abu Ahmed; Mehra, Sucheta; Wu, Lee S-F; Rashid, Mahbubar; Labrique, Alain B; Christian, Parul; West, Keith P

2013-02-28

Equations for predicting body composition from bioelectrical impedance analysis (BIA) parameters are age-, sex- and population-specific. Currently there are no equations applicable to women of reproductive age in rural South Asia. Hence, we developed equations for estimating total body water (TBW), fat-free mass (FFM) and fat mass in rural Bangladeshi women using BIA, with ²H₂O dilution as the criterion method. Women of reproductive age, participating in a community-based placebo-controlled trial of vitamin A or β-carotene supplementation, were enrolled at 19·7 (SD 9·3) weeks postpartum in a study to measure body composition by ²H₂O dilution and impedance at 50 kHz using multi-frequency BIA (n 147), and resistance at 50 kHz using single-frequency BIA (n 82). TBW (kg) by ²H2O dilution was used to derive prediction equations for body composition from BIA measures. The prediction equation was applied to resistance measures obtained at 13 weeks postpartum in a larger population of postpartum women (n 1020). TBW, FFM and fat were 22·6 (SD 2·7), 30·9 (SD 3·7) and 10·2 (SD 3·8) kg by ²H₂O dilution. Height²/impedance or height²/resistance and weight provided the best estimate of TBW, with adjusted R² 0·78 and 0·76, and with paired absolute differences in TBW of 0·02 (SD 1·33) and 0·00 (SD 1·28) kg, respectively, between BIA and ²H₂O. In the larger sample, values for TBW, FFM and fat were 23·8, 32·5 and 10·3 kg, respectively. BIA can be an important tool for assessing body composition in women of reproductive age in rural South Asia where poor maternal nutrition is common.

Malnutrition and its association with inflammation and vascular disease in children on maintenance dialysis.

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Canpolat, Nur; Caliskan, Salim; Sever, Lale; Tasdemir, Mehmet; Ekmekci, Ozlem Balcı; Pehlivan, Gulseren; Shroff, Rukshana

2013-11-01

Malnutrition is associated with both inflammation and atherosclerotic cardiovascular disease in adults with chronic kidney disease. We studied the prevalence of malnutrition and its possible associations with inflammation and vascular disease in children on chronic dialysis. Thirty-three patients on maintenance dialysis (18 peritoneal dialysis, 15 hemodialysis) and 19 age- and gender- matched healthy controls were studied. Nutritional status was assessed by anthropometric measurements including body mass index (BMI), upper arm measurements, multifrequency bioimpedance analysis (BIA) and serum levels of albumin, prealbumin, and cholesterol. Inflammation was assessed by serum levels of C-reactive protein (CRP), interleukin (IL)-6, and tumor necrosis factor (TNF)-alpha. The carotid artery intima thickness (cIMT) was measured to assess vascular disease. Compared with healthy children, patients had lower anthropometric measurements (P Malnutrition was present in 8 (24%) and lower BIA-based fat mass was independently associated with higher IL-6 levels (P = 0.035). An increased cIMT was present in 16 (48.5%); however, there was no difference in cIMT-SDS between patients with and without malnutrition. Carotid IMT did not show any association with nutritional indices; but positively correlated with serum IL-6 (P = 0.037), CRP (P = 0.012), and iPTH (P = 0.009), and independently associated with only iPTH (P = 0.018). Children on dialysis are at an increased risk of malnutrition, inflammation, and vascular disease. Although each of these three conditions exists, there is no interaction among them all. We postulate that the malnutrition-inflammation-atherosclerosis (MIA) complex might not exist in pediatric dialysis patients.

Business Impact Analysis Terkait Penanganan dan Pemulihan Terhadap Bencana di PT Bank XYZ

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Rubil Rubil

2012-12-01

Full Text Available For each company, disasters may have diverse impacts either financially or non-financially. Therefore, a company requires a business continuity plan. One important factor in developing such plan is Business Impact Analysis (BIA. With BIA, a company can identify and analyze Critical Business Functions (CBFs and potential impacts on the business whether operationally or financially, and further, business recovery priority, strategy and solution can be determined following a disaster.Methodologies used in developing this BIA are quantitativeand qualitative where for aspects related to financials, quantitive method is used. Meanwhile, for those aspects\\ related to non-financial areas, qualitative method is used. The development of this BIA was done through the dissemination of questionnaires to 62 business units in PT Bank XYZ. To draw the BIA, eight parameters were used, where as for the final result, there were three criticality levels found in the business units of PT Bank XYZ, i.e. very critical level - 18 business units (29%, critical level - 23 business units (37% and less critical level – 21 business units (34%. In addition, there were 71 applications used by CBFs. Based on the results of this study, PT Bank XYZ can determine the priority and key strategies for business units that require handling and recovery when a disaster occurs to maintain the bank's business operation's continuity and sustainability.Withthat, the company can minimize the potential loss resulted from a disaster.

The Impact of Feet Callosities, Arm Posture, and Usage of Electrolyte Wipes on Body Composition by Bioelectrical Impedance Analysis in Morbidly Obese Adults.

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Roekenes, Jessica; Strømmen, Magnus; Kulseng, Bård; Martins, Catia

2015-01-01

This study evaluated the impact of feet callosities, arm posture, and use of electrolyte wipes on body composition measurements by bioelectrical impedance analysis (BIA) in morbidly obese adults. 36 morbidly obese patients (13 males, aged 28-70 years, BMI 41.6 ± 4.3 kg/m2) with moderate/severe feet callosities participated in this study. Body composition (percent body fat (%BF)) was measured while fasting using multi-frequency BIA (InBody 720®), before and after removal of callosities, with and without InBody® electrolyte wipes and custom-built auxiliary pads (to assess arm posture impact). Results from BIA were compared to air displacement plethysmography (ADP, BodPod®). Median %BF was significantly higher with auxiliary pads than without (50.1 (interquartile range 8.2) vs. 49.3 (interquartile range 9.1); p interquartile range 9.1) vs. 50.0 (interquartile range 7.9); NS) or use of wipes (49.6 (interquartile range 8.5) vs. 49.3 (interquartile range 9.1); NS). No differences in %BF were found between BIA and ADP (49.1 (IQR: 8.9) vs. 49.3 (IQR: 9.1); NS). Arm posture has a significant impact on %BF assessed by BIA, contrary to the presence of feet callosities and use of electrolyte wipes. Arm posture standardization during BIA for body composition assessment is, therefore, recommended. © 2015 S. Karger GmbH, Freiburg.

Respiration monitoring by Electrical Bioimpedance (EBI) Technique in a group of healthy males. Calibration equations

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Balleza, M; Vargas, M; Delgadillo, I; Kashina, S; Huerta, M R; Moreno, G

2017-01-01

Several research groups have proposed the electrical impedance tomography (EIT) in order to analyse lung ventilation. With the use of 16 electrodes, the EIT is capable to obtain a set of transversal section images of thorax. In previous works, we have obtained an alternating signal in terms of impedance corresponding to respiration from EIT images. Then, in order to transform those impedance changes into a measurable volume signal a set of calibration equations has been obtained. However, EIT technique is still expensive to attend outpatients in basics hospitals. For that reason, we propose the use of electrical bioimpedance (EBI) technique to monitor respiration behaviour. The aim of this study was to obtain a set of calibration equations to transform EBI impedance changes determined at 4 different frequencies into a measurable volume signal. In this study a group of 8 healthy males was assessed. From obtained results, a high mathematical adjustment in the group calibrations equations was evidenced. Then, the volume determinations obtained by EBI were compared with those obtained by our gold standard. Therefore, despite EBI does not provide a complete information about impedance vectors of lung compared with EIT, it is possible to monitor the respiration. (paper)

Nova proposta de teste incremental de remada na avaliação aeróbia de surfistas

OpenAIRE

CANOZZI, Felipe Bercht; SILVEIRA, Bruno Honorato da; OLIVEIRA, Mariana Fernandes Mendes de; CAPUTO, Fabrízio

2015-01-01

ResumoOs objetivos desse estudo foram: 1) verificar as respostas do lactato sanguíneo e da frequência cardíaca (FC) durante um protocolo de campo específico de remada no surfe; 2) correlacionar os índices de capacidade e potência aeróbia determinados nesse protocolo específico com o tempo de prática da modalidade e variáveis antropométricas. Participaram deste estudo nove sujeitos (24 ± 4,5 anos; 72,2 ± 6,7 kg; 178,4 ± 4,8 cm) que foram submetidos a um teste progressivo intermitente de remada...

Validation of two portable bioelectrical impedance analyses for the assessment of body composition in school age children.

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Li-Wen Lee

Full Text Available Bioelectrical impedance analysis (BIA is a convenient and child-friendly method for longitudinal analysis of changes in body composition. However, most validation studies of BIA have been performed on adult Caucasians. The present cross-sectional study investigated the validity of two portable BIA devices, the Inbody 230 (BIA8MF and the Tanita BC-418 (BIA8SF, in healthy Taiwanese children.Children aged 7-12 years (72 boys and 78 girls were recruited. Body composition was measured by the BIA8SF and the BIA8MF. Dual X-ray absorptiometry (DXA was used as the reference method.There were strong linear correlations in body composition measurements between the BIA8SF and DXA and between the BIA8MF and DXA. Both BIAs underestimated fat mass (FM and percentage body fat (%BF relative to DXA in both genders The degree of agreement in lean body mass (LBM, FM, and %BF estimates was higher between BIA8MF and DXA than between BIA8SF and DXA. The Lin's concordance correlation coefficient (ρc for LBM8MF met the criteria of substantial to perfect agreement whereas the ρc for FM8MF met the criteria of fair to substantial agreement. Bland-Altman analysis showed a clinically acceptable agreement between LBM measures by BIA8MF and DXA. The limit of agreement in %BF estimation by BIA and DXA were wide and the errors were clinically important. For the estimation of ALM, BIA8SF and BIA8MF both provided poor accuracy.For all children, LBM measures were precise and accurate using the BIA8MF whereas clinically significant errors occurred in FM and %BF estimates. Both BIAs underestimated FM and %BF in children. Thus, the body composition results obtained using the inbuilt equations of the BIA8SF and BIA8MF should be interpreted with caution, and high quality validation studies for specific subgroups of children are required prior to field research.

Prevalence of malnutrition and validation of bioelectrical impedance analysis for the assessment of body composition in patients with systemic sclerosis.

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Spanjer, Moon J; Bultink, Irene E M; de van der Schueren, Marian A E; Voskuyl, Alexandre E

2017-06-01

The aims were to assess the prevalence of malnutrition and to validate bioelectrical impedance analysis (BIA) against whole-body DXA for the assessment of body composition in patients with SSc. Malnutrition was defined as BMI 10% in combination with a fat-free mass index (FFMI) 70 years). Body composition was assessed in 72 patients with whole-body DXA (Hologic, Discovery A) and BIA (Bodystat Quadscan 400). The manufacturer's equation and the Geneva equation were used to estimate FFM and fat mass. The agreement between BIA and whole-body DXA was assessed with Bland-Altman analysis and intraclass correlation coefficient. Malnutrition was found in 8.3% (n = 6) and low FFMI in 20.8% (n = 15) of patients. The mean difference in FFM between BIA and DXA applying the Geneva equation was 0.02 ( s . d . 2.4) kg, intraclass correlation coefficient 0.97 (95% CI: 0.95, 0.98). Limits of agreement were ±4.6 kg. The manufacturer's equation was less adequate to predict FFM. This study shows a relatively low prevalence of malnutrition in comparison with other studies, but a high prevalence of low FFMI, underlining the necessity of measuring body composition in SSc patients with a standardized and validated method. A good validity of BIA in determining FFM was found at a group level, while at an individual level the FFM may vary by 4.6 kg. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Bioimpedance identifies body fluid loss after exercise in the heat: a pilot study with body cooling.

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Hannes Gatterer

Full Text Available Assessment of post-exercise changes in hydration with bioimpedance (BI is complicated by physiological adaptations that affect resistance (R and reactance (Xc values. This study investigated exercise-induced changes in R and Xc, independently and in bioelectrical impedance vector analysis, when factors such as increased skin temperature and blood flow and surface electrolyte accumulation are eliminated with a cold shower.Healthy males (n = 14, 24.1±1.7 yr; height (H: 182.4±5.6 cm, body mass: 72.3±6.3 kg exercised for 1 hr at a self-rated intensity (15 BORG in an environmental chamber (33°C and 50% relative humidity, then had a cold shower (15 min. Before the run BI, body mass, hematocrit and Posm were measured. After the shower body mass was measured; BI measurements were performed continuously every 20 minutes until R reached a stable level, then hematocrit and Posm were measured again.Compared to pre-trial measurements body mass decreased after the run and Posm, Hct, R/H and Xc/H increased (p<0.05 with a corresponding lengthening of the impedance vector along the major axis of the tolerance ellipse (p<0.001. Changes in Posm were negatively related to changes in body mass (r = -0.564, p = 0.036 and changes in Xc/H (r = -0.577, p = 0.041.Present findings showed that after a bout of exercise-induced dehydration followed by cold shower the impedance vector lengthened that indicates fluid loss. Additionally, BI values might be useful to evaluate fluid shifts between compartments as lower intracellular fluid loss (changed Xc/R indicated greater Posm increase.

The relationship between bioelectrical impedance phase angle and subjective global assessment in advanced colorectal cancer

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Grutsch James F

2008-06-01

Full Text Available Abstract Background Bioelectrical Impedance (BIA derived phase angle is increasingly being used as an objective indicator of nutritional status in advanced cancer. Subjective Global Assessment (SGA is a subjective method of nutritional status. The objective of this study was to investigate the association between BIA derived phase angle and SGA in advanced colorectal cancer. Methods We evaluated a case series of 73 stages III and IV colorectal cancer patients. Patients were classified as either well-nourished or malnourished using the SGA. BIA was conducted on all patients and phase angle was calculated. The correlation between phase angle and SGA was studied using Spearman correlation coefficient. Receiver Operating Characteristic curves were estimated using the non-parametric method to determine the optimal cut-off levels of phase angle. Results Well-nourished patients had a statistically significantly higher (p = 0.005 median phase angle score (6.12 as compared to those who were malnourished (5.18. The Spearman rank correlation coefficient between phase angle and SGA was found to be 0.33 (p = 0.004, suggesting better nutritional status with higher phase angle scores. A phase angle cut-off of 5.2 was 51.7% sensitive and 79.5% specific whereas a cut-off of 6.0 was 82.8% sensitive and 54.5% specific in detecting malnutrition. Interestingly, a phase angle cut-off of 5.9 demonstrated high diagnostic accuracy in males who had failed primary treatment for advanced colorectal cancer. Conclusion Our study suggests that bioimpedance phase angle is a potential nutritional indicator in advanced colorectal cancer. Further research is needed to elucidate the optimal cut-off levels of phase angle that can be incorporated into the oncology clinic for better nutritional evaluation and management.

Estimation of prevalence of sarcopenia by using a new bioelectrical impedance analysis in Chinese community-dwelling elderly people.

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Wang, Hui; Hai, Shan; Cao, Li; Zhou, Jianghua; Liu, Ping; Dong, Bi-Rong

2016-12-28

The aim of the present study was to validate the usefulness of the new octapolar multifrequency bioelectrical impedance analysis (BIA) for assessment of appendicular skeletal muscle mass (ASM) by comparing it with that of dual-energy X-ray absorptiometry (DXA) and to investigate the prevalence of sarcopenia in Chinese community-dwelling elderly according to Asian Working Group for Sarcopenia (AWGS) definition. A cross-sectional study was conducted in communities of Chengdu, China. A total of 944 community-dwelling elderly adults aged ≥60 years were included. ASM was measured by using DXA as a criterion method to validate a standing eight-electrode multifrequency BIA (InBody 720), followed by a further estimation of the prevalence of sarcopenia according the AWGS definition. In the Bland-Altman analysis, no significant difference was found between DXA and BIA based on the ASM measurements. The prevalence of AWGS-defined sarcopenia was 12.5% in the elderly women and 8.2% in the elderly men. BIA is suitable for body composition monitoring (ASM) in elderly Chinese as a fast, noninvasive, and convenient method; therefore, it may be a better choice in large epidemiological studies in the Chinese population. The prevalence of AWGS-defined sarcopenia was approximately 10.4% and increased with age in the Chinese community-dwelling elderly in this study.

Estimation of body fluids with bioimpedance spectroscopy: state of the art methods and proposal of novel methods

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Buendia, R; Seoane, F; Lindecrantz, K; Bosaeus, I; Gil-Pita, R; Johannsson, G; Ellegård, L; Ward, L C

2015-01-01

Determination of body fluids is a useful common practice in determination of disease mechanisms and treatments. Bioimpedance spectroscopy (BIS) methods are non-invasive, inexpensive and rapid alternatives to reference methods such as tracer dilution. However, they are indirect and their robustness and validity are unclear. In this article, state of the art methods are reviewed, their drawbacks identified and new methods are proposed. All methods were tested on a clinical database of patients receiving growth hormone replacement therapy. Results indicated that most BIS methods are similarly accurate (e.g.  <  0.5   ±   3.0% mean percentage difference for total body water) for estimation of body fluids. A new model for calculation is proposed that performs equally well for all fluid compartments (total body water, extra- and intracellular water). It is suggested that the main source of error in extracellular water estimation is due to anisotropy, in total body water estimation to the uncertainty associated with intracellular resistivity and in determination of intracellular water a combination of both. (paper)

Estimativa da massa muscular esquelética em mulheres idosas: validade da impedância bioelétrica Validity of bioelectrical impedance analysis for the estimation of skeletal muscle mass in elderly women

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Cassiano Ricardo Rech

2010-04-01

Full Text Available O presente estudo tem como objetivos: a verificar a concordância entre os métodos da impedância bioelétrica (BIA e da absortometria radiológica de dupla energia (DXA para a estimativa da massa muscular esquelética (MME; e b analisar o poder preditivo de variáveis antropométricas e da BIA para a predição da MME em idosas. Foram avaliadas 120 mulheres (60 a 81 anos, residentes na região Sul do Brasil. Mensuraram-se as variáveis antropométricas (massa corporal e estatura; a resistência e hidratação dos tecidos livres de gordura foram medidas pela técnica da BIA tetrapolar (Biodinamics - BF-310, e pela DXA de corpo inteiro (Lunar Prodigy DF + 14319 Radiation e software 7.52.002 DPX-L. A diferença entre os métodos foi verificada pelo teste t pareado, análise dos resíduos e o coeficiente de correlação. O valor preditivo das variáveis antropométricas e de BIA foi verificado pela regressão linear múltipla, adotando nível de significância de p 0,01. Observou-se que a BIA subestimou em média 0,8kg (IC95%: -3,7; 2,0kg a MME, quando comparada com a DXA. Foi observada alta correlação entre os métodos (r² = 0,75; p The objectives of the present study were: a to determine the agreement between bioelectrical impedance analysis (BIA and dual-energy X-ray absorptiometry (DXA for the estimation of skeletal muscle mass (SMM, and b to analyze the predictive power of anthropometric variables and BIA for the prediction of SMM in elderly women. A total of 120 women (60 to 81 years, living in the southern region of Brazil, were studied. Anthropometric variables (body weight and height were measured. Resistance and hydration of fat-free tissues were measured by tetrapolar BIA (Biodynamics, BF-310 and by whole-body DXA (Lunar Prodigy DF + 14319 Radiation and DPX-L software, version 7.52.002. Differences between methods were determined using the paired t-test, analysis of residuals and correlation coefficient. The predictive value of the

Clinical, analytical and bioimpedance characteristics of persistently overhydrated haemodialysis patients.

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Castellano, Sandra; Palomares, Inés; Molina, Manuel; Pérez-García, Rafael; Aljama, Pedro; Ramos, Rosa; Merello, J Ignacio

2014-11-17

Fluid overload is an important and modifiable cardiovascular risk factor for haemodialysis patients. So far, the diagnosis was based on clinical methods alone. Nowadays, we have new tools to assess more objectively the hydration status of the patients on haemodialysis, as BCM (Body Composition Monitor). A Relative Overhydration (AvROH) higher than 15% (it means, Absolute Overhydration or AWOH higher than 2.5 Litres) is associated to greater risk in haemodialysis. However, there is a group of maintained hyperhydrated patients. The aim of the present study is to identify the characteristics of patients with maintained hyperhydrated status (AvROH higher than 15% or AWOH higher than 2.5 liters). The secondary aim is to show the hemodynamic and analytical changes that are related to the reduction in hyperhydration status. Longitudinal cohort study during six months in 2959 patients in haemodialysis (HD) that are grouped according to their hydration status by BCM. And we compare their clinical, analytical and bioimpedance spectroscopy parameters. The change in overhydration status is followed by a decrease in blood pressure and the need for hypotensive drugs (AHT) and erythropoiesis stimulating agents (ESA). The target hydration status is not reached by two subgroups of patients. First, in diabetic patients with a high comorbidity index and high number of hypotensive drugs (AHT) but a great positive sodium gradient during dialysis sessions; and, younger non-diabetic patients with longer time on hemodialysis and positive sodium gradient, lower fat tissue index (FTI) but similar lean tissue index (LTI) and albumin than those with a reduction in hyperhydration status. Those patients with a reduction in hyperhydration status, also show a better control in blood pressure and anemia with less number of AHT and ESA. The maintained hyperhydrated patients, diabetic patients with many comorbidities and young men patients with longer time on hemodialysis and non-adherence treatment

Comparison of body fat using various bioelectrical impedance analyzers in university students

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Petr Kutáč

2015-12-01

Full Text Available Background: At present, the portfolio of devices using the bioelectrical impedance (BIA method is continuously expanding as a result of the wide use of this method in the field as measurements by this method are fast and staff training is simple and reasonably priced. Nonetheless, the problem is that despite using the same method, bioimpedance analyzers can differ in many parameters. They use different electric current frequencies, a different number of electrodes and the electric current may be conducted through different parts of the body.Objective: The main objective of the study is to compare and evaluate the differences of values of the analysis of the body fat of university students measured by BIA analyzers that differ in the applied electric current frequency, number of electrodes and flow of the electric current through the individual body parts.Methods: The research included 125 participants (70 male and 55 female. The measurements were taken by the following analyzers: Tanita 418 MA, InBody 720, InBody R20 and Omron BF 300.Results: The differences in the mean values of the body fat representation between the used analyzers in men ranged from 0.1 to 3.4% and from 0.0 to 2.4 kg, in women from 0.5 to 6.5% and from 0.4 to 3.8 kg in relation to the used analyzer.Conclusions: In men with regular physical activity, the values measured by InBody R20 were statistically and practically different. The analyzer measured higher values that other analyzers. In women, there were statistically and practically significant differences in the values measured by Omron BF 300. This analyzer measured lower values than other analyzers.

Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition and metabolic outcomes at 7–9 years of age

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Rush, Elaine C; Plank, Lindsay D; Lu, Jun; Obolonkin, Victor; Coat, Suzette

2018-01-01

Objective To compare body composition and metabolic outcomes at 7–9 years in offspring of women with gestational diabetes (GDM) randomized to metformin (±insulin) or insulin treatment during pregnancy. Research design and methods Children were assessed at 7 years in Adelaide (n=109/181) and 9 years in Auckland (n=99/396) by anthropometry, bioimpedance analysis (BIA), dual-energy X-ray absorptiometry (DXA), magnetic resonance imaging (MRI) (n=92/99) and fasting bloods (n=82/99). Results In the Adelaide subgroup, mothers were similar at enrollment. Women randomized to metformin versus insulin had higher treatment glycemia (p=0.002) and more infants with birth weight >90th percentile (20.7% vs 5.9%; p=0.029). At 7 years, there were no differences in offspring measures. In Auckland, at enrollment, women randomized to metformin had a higher body mass index (BMI) (p=0.08) but gained less weight during treatment (p=0.07). Offspring birth measures were similar. At 9 years, metformin offspring were larger by measures of weight, arm and waist circumferences, waist:height (p<0.05); BMI, triceps skinfold (p=0.05); DXA fat mass and lean mass (p=0.07); MRI abdominal fat volume (p=0.051). Body fat percent was similar between treatment groups by DXA and BIA. Abdominal fat percentages (visceral adipose tissue, subcutaneous adipose tissue and liver) were similar by MRI. Fasting glucose, triglyceride, insulin, insulin resistance, glycosylated hemoglobin (HbA1c), cholesterol, liver transaminases, leptin and adiponectin were similar. Conclusions Metformin or insulin for GDM was associated with similar offspring total and abdominal body fat percent and metabolic measures at 7–9 years. Metformin-exposed children were larger at 9 years. Metformin may interact with fetal environmental factors to influence offspring outcomes. PMID:29682291

Archives of Voivodship Committee of Polish United Workers’ Party in Biała Podlaska

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Dariusz Magier

2010-12-01

Full Text Available Documentation generated by the communist party after World War II constituted the part of Polish archival heritage. However, Party’s archives were not supervised by nationalarchival network. At the beginning they were storehouses of acts, and since 1955 they had been taken over by propaganda sections of voivodship committees of PZPR (Polish United Workers’ Party and later transformed into the archives of voivodship committees of the Party. The task to preserve documentation generated by the structures of the communist party in Poland was subsequently supervised by: Party HistoryInstitute at KC PZPR (Central Committee of Polish United Workers’ Party, Archives of KC PZPR, and since 1971 Central Archives of KC PZPR. Together with the archives of voivodship committees the net with its own regulations, staff and archival methodology was created. This article gives a detailed description of the activity of the organizational unit,that is the archives of the voivodship committee of the communist party. One of the smallest committees existing in Poland, a provincial Voivodship Committee of PZPR in Biała Podlaska, which operated from 1975 to 1990, serves as an example. The article discusses the reporting structure, handing-over, analysis and preservation of acts, means of recording, premises, system of training and control as well as characterizes the role of a supervisor of the Party’s voidovdship committee Archives played in the archives and chancery.

The effect of intake of water on the final values of body composition parameters in active athletes using two different bioimpedance analyzers

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Petr Kutáč

2014-06-01

Full Text Available Background:The method of bioelectrical impedance (BIA is frequently used to estimate body composition in sports. The total body water (TBW is the basic variable that BIA measures. That implies the degree of sensitivity of BIA to the hydration of the organism, which is also demonstrated by the principles of measurement that primarily relate to the hydration of the organism. It is difficult to provide standard hydration of the organism of subjects prior to measurements when taking the measurements in the field. Objective:The objective of the study is to assess the changes in the final values of the selected body composition parameters in soccer players caused by intake of water, using two devices commonly used in the field. Methods:The research was performed in a group of 33 soccer players (mean age 20.30 ± 1.18 years. The measurements were taken using Tanita BC 418 MA (frequency 50 kHz and Nutriguard-M (frequency 100 kHz. To evaluate the effect of water intake, we took two measurements before and after the intake of 500 ml of water. The parameters measured by Tanita BC 418 MA were body weight (BW, total body water (TBW, body fat (BF, fat free mass (FFM. Nutriguard-M was used to measure total body water (TBW, intra and extracellular water (ICW and ECW, body fat (BF, fat free mass (FFM, intra and extracellular mass (BCM and ECM. The differences in the means (M1 and M2 of the monitored parameters were evaluated using the Paired Samples t-test. In statistically significant differences in the mean, the practical significance was also verified using the effect of size (Cohen's d. Results:The Tanita device showed statistically significant differences after the intake of 500 ml in parameters BW (+0.42 kg, BF (+0.39 kg, +0.53% and TBW (-0.38%. As for the Nutriguard device, statistically significant differences were found in parameters TBW (+0.77 kg, ICW (+0.83 kg, FFM (+1.05 kg, BCM (+0.79 kg and ECM/BCM (-0.01. Conclusion

The diagnostic accuracy of multi-frequency bioelectrical impedance analysis in diagnosing dehydration after stroke

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Kafri, Mohannad W.; Myint, Phyo Kyaw; Doherty, Danielle; Wilson, Alexander Hugh; Potter, John F.; Hooper, Lee

2013-01-01

Background Non-invasive methods for detecting water-loss dehydration following acute stroke would be clinically useful. We evaluated the diagnostic accuracy of multi-frequency bioelectrical impedance analysis (MF-BIA) against reference standards serum osmolality and osmolarity. Material/Methods Patients admitted to an acute stroke unit were recruited. Blood samples for electrolytes and osmolality were taken within 20 minutes of MF-BIA. Total body water (TBW%), intracellular (ICW%) and extracellular water (ECW%), as percentages of total body weight, were calculated by MF-BIA equipment and from impedance measures using published equations for older people. These were compared to hydration status (based on serum osmolality and calculated osmolarity). The most promising Receiver Operating Characteristics curves were plotted. Results 27 stroke patients were recruited (mean age 71.3, SD10.7). Only a TBW% cut-off at 46% was consistent with current dehydration (serum osmolality >300 mOsm/kg) and TBW% at 47% impending dehydration (calculated osmolarity ≥295–300 mOsm/L) with sensitivity and specificity both >60%. Even here diagnostic accuracy of MF-BIA was poor, a third of those with dehydration were wrongly classified as hydrated and a third classified as dehydrated were well hydrated. Secondary analyses assessing diagnostic accuracy of TBW% for men and women separately, and using TBW as a percentage of lean body mass showed some promise, but did not provide diagnostically accurate measures across the population. Conclusions MF-BIA appears ineffective at diagnosing water-loss dehydration after stroke and cannot be recommended as a test for dehydration, but separating assessment by sex, and using TBW as a percentage of lean body weight may warrant further investigation. PMID:23839255

Fat-free mass prediction equations for bioelectric impedance analysis compared to dual energy X-ray absorptiometry in obese adolescents: a validation study.

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Hofsteenge, Geesje H; Chinapaw, Mai J M; Weijs, Peter J M

2015-10-15

In clinical practice, patient friendly methods to assess body composition in obese adolescents are needed. Therefore, the bioelectrical impedance analysis (BIA) related fat-free mass (FFM) prediction equations (FFM-BIA) were evaluated in obese adolescents (age 11-18 years) compared to FFM measured by dual-energy x-ray absorptiometry (FFM-DXA) and a new population specific FFM-BIA equation is developed. After an overnight fast, the subjects attended the outpatient clinic. After measuring height and weight, a full body scan by dual-energy x-ray absorptiometry (DXA) and a BIA measurement was performed. Thirteen predictive FFM-BIA equations based on weight, height, age, resistance, reactance and/or impedance were systematically selected and compared to FFM-DXA. Accuracy of FFM-BIA equations was evaluated by the percentage adolescents predicted within 5% of FFM-DXA measured, the mean percentage difference between predicted and measured values (bias) and the Root Mean Squared prediction Error (RMSE). Multiple linear regression was conducted to develop a new BIA equation. Validation was based on 103 adolescents (60% girls), age 14.5 (sd1.7) years, weight 94.1 (sd15.6) kg and FFM-DXA of 56.1 (sd9.8) kg. The percentage accurate estimations varied between equations from 0 to 68%; bias ranged from -29.3 to +36.3% and RMSE ranged from 2.8 to 12.4 kg. An alternative prediction equation was developed: FFM = 0.527 * H(cm)(2)/Imp + 0.306 * weight - 1.862 (R(2) = 0.92, SEE = 2.85 kg). Percentage accurate prediction was 76%. Compared to DXA, the Gray equation underestimated the FFM with 0.4 kg (55.7 ± 8.3), had an RMSE of 3.2 kg, 63% accurate prediction and the smallest bias of (-0.1%). When split by sex, the Gray equation had the narrowest range in accurate predictions, bias, and RMSE. For the assessment of FFM with BIA, the Gray-FFM equation appears to be the most accurate, but 63% is still not at an acceptable accuracy level for obese adolescents. The new equation appears to

Utility of Volume Assessment Using Bioelectrical Impedance Analysis in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Prospective Observational Study

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Ki Hyun Park

2017-08-01

Full Text Available Background Fluid overload prior to continuous renal replacement therapy (CRRT is an important prognostic factor. Thus, precise evaluation of fluid status is necessary to treat such patients. In this study, we investigated whether fluid assessment using bioelectrical impedance analysis (BIA can predict outcomes in critically ill patients requiring CRRT. Methods A prospective observational study was performed in patients who were admitted to the intensive care unit and who required CRRT. BIA was conducted before CRRT; then, the ratio of extracellular water to total body water (ECW/TBW was derived to estimate volume status. Results A total of 31 patients treated with CRRT were included. There were 18 men (58.1%, and the median age was 67 years (interquartile range, 51 to 78 years. Fourteen patients (45.2% died within 28 days after CRRT initiation. Patients were divided into 16 with ECW/TBW ≥0.41 and 15 with ECW/TBW <0.41. Survival rate within 28 days was different between the two groups (P = 0.044. Cox regression analysis revealed a relationship between ECW/TBW ≥0.41 and 28-day mortality, but it was not statistically significant (hazard ratio, 3.0; 95% confidence interval, 0.9 to 9.8; P = 0.061. Lastly, the area under the curve of ECW/TBW for 28-day mortality was analyzed. The area under the curve of ECW/TBW was 0.73 (95% confidence interval, 0.54 to 0.92, and this was significant (P = 0.037. Conclusions Fluid status can be assessed using BIA in critically ill patients requiring CRRT, and BIA can predict mortality. Further large trials are needed to confirm the usefulness of BIA in critically ill patients.

BIOELECTRICAL IMPEDANCE VECTOR ANALYSIS IDENTIFIES SARCOPENIA IN NURSING HOME RESIDENTS

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Loss of muscle mass and water shifts between body compartments are contributing factors to frailty in the elderly. The body composition changes are especially pronounced in institutionalized elderly. We investigated the ability of single-frequency bioelectrical impedance analysis (BIA) to identify b...

Validation of bioelectrical impedance analysis in Ethiopian adults with HIV

DEFF Research Database (Denmark)

Hegelund, Maria H; Wells, Jonathan C; Girma, Tsinuel

2017-01-01

in populations of different ethnic origin and health status. The aim of the present study was to test the validity of BIA in Ethiopian antiretroviral-naive HIV patients. BIA was validated against the 2H dilution technique by comparing fat-free mass (FFM) measured by the two methods using paired t tests and Bland...... % were underweight with a BMI below 18·5 kg/m2. There were no differences in FFM between the methods. Overall, BIA slightly underestimated FFM by 0·1 kg (-0·1, 95 % CI -0·3, 0·2 kg). The Bland-Altman plot indicated acceptable agreement with an upper limit of agreement of 4·5 kg and a lower limit...... of agreement of -4·6 kg, but with a small correlation between the mean difference and the average FFM. BIA slightly overestimated FFM at low values compared with the 2H dilution technique, while it slightly underestimated FFM at high values. In conclusion, BIA proved to be valid in this population and may...

A meta-analysis of the relationships between body checking, body image avoidance, body image dissatisfaction, mood, and disordered eating.

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Walker, D Catherine; White, Emily K; Srinivasan, Vamshek J

2018-04-16

Body checking (BC) and body image avoidance (BIA) have been proposed as etiological and maintaining mechanisms for eating disorder (ED) pathology. To date, no comprehensive review summarizes the relationships of BC and BIA with ED pathology, body image dissatisfaction, or mood/affect. Meta-analyses examined the relationships of BC and BIA with ED pathology, body image dissatisfaction, and mood/affect. Gender, publication status, and presence or absence of ED diagnoses were examined as potential moderators. Results showed strong relationships between BC and ED pathology (ρ = 0.588) and BC and body image dissatisfaction (ρ = 0.631) and a moderate relationship between BC and mood/affect (ρ = 0.385). Similarly, results showed strong relationships between BIA and ED pathology (ρ = 0.553) and BIA and body image dissatisfaction (ρ = 0.543) and a moderate relationship between BIA and mood/affect (ρ = 0.392). Overall, limited evidence supported publication bias; however, publication bias may exist in the relationship between BIA and body image dissatisfaction in the literature. Subgroup moderator analyses suggested that gender moderates the strength of the relationships between BC and ED pathology, body image dissatisfaction, and mood/affect and between BIA and body image dissatisfaction. Results are consistent with cognitive-behavioral models of ED pathology that suggest BC and BIA are behavioral expressions of overvaluation of weight and shape. Notably, more published research has investigated BC than BIA. Future studies, incorporating methods such as meta-analytic structural equation modeling, should examine these variables to further test cognitive-behavioral models of ED development and maintenance. © 2018 Wiley Periodicals, Inc.

New high-resolution record of Holocene climate change in the Weddell Sea from combined biomarker analysis of the Patriot Hills blue ice area

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Fogwill, Christopher; Turney, Chris; Baker, Andy; Ellis, Bethany; Cooper, Alan; Etheridge, David; Rubino, Mauro; Thornton, David; Fernando, Francisco; Bird, Michale; Munksgaard, Niels

2017-04-01

We report preliminary analysis of biomarkers (including dissolved organic matter (DOM) and DNA) from the Patriot Hills blue ice area (BIA), from the Ellsworth Mountains in the Weddell Sea Embayment. Preliminary isotopic and multiple gas analysis (CO2, CH4, N2O and CO) demonstrate that the Holocene comprises more than 50% of the 800m long BIA record, and in combination isotopic and biomarker analysis reveals a remarkable record of centennial variability through the Holocene in this sector of the Weddell Sea. Analysis using a Horiba Aqualog - which measures the fluorescence of DOM by producing a map of the fluorescence through an excitation-emission matrix (EEM) - identifies the presence of two marine protein-like components in both modern snow pit samples and within the Holocene part of Patriot Hills BIA transect. Intriguingly, the modern seasonal trends in DOM, recorded in contemporary snow pits, have relatively low signals compared to those recorded in the mid-Holocene record, suggesting a reduction in DOM signal in contemporary times. Given that the δD excess data suggests the source of precipitation has remained constant through the Holocene, the biomarker signal must relate to multi-year marine productivity signals from the Weddell Sea. The marked variability in DOM between the mid-Holocene and contemporary times can only relate to periods of sustained, enhanced biological productivity in the Weddell Sea associated with shifts in Southern Annular Mode, sea ice variability, changes in ventilation or polynya activity. Here we discuss the possible drivers of these changes and describe how this approach at this BIA could benefit conventional ice core records regionally.

The differential Howland current source with high signal to noise ratio for bioimpedance measurement system

Energy Technology Data Exchange (ETDEWEB)

Liu, Jinzhen; Li, Gang; Lin, Ling, E-mail: linling@tju.edu.cn [State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin, People' s Republic of China, and Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments, Tianjin University, Tianjin (China); Qiao, Xiaoyan [College of Physics and Electronic Engineering, Shanxi University, Shanxi (China); Wang, Mengjun [School of Information Engineering, Hebei University of Technology, Tianjin (China); Zhang, Weibo [Institute of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences, Beijing (China)

2014-05-15

The stability and signal to noise ratio (SNR) of the current source circuit are the important factors contributing to enhance the accuracy and sensitivity in bioimpedance measurement system. In this paper we propose a new differential Howland topology current source and evaluate its output characters by simulation and actual measurement. The results include (1) the output current and impedance in high frequencies are stabilized after compensation methods. And the stability of output current in the differential current source circuit (DCSC) is 0.2%. (2) The output impedance of two current circuits below the frequency of 200 KHz is above 1 MΩ, and below 1 MHz the output impedance can arrive to 200 KΩ. Then in total the output impedance of the DCSC is higher than that of the Howland current source circuit (HCSC). (3) The SNR of the DCSC are 85.64 dB and 65 dB in the simulation and actual measurement with 10 KHz, which illustrates that the DCSC effectively eliminates the common mode interference. (4) The maximum load in the DCSC is twice as much as that of the HCSC. Lastly a two-dimensional phantom electrical impedance tomography is well reconstructed with the proposed HCSC. Therefore, the measured performance shows that the DCSC can significantly improve the output impedance, the stability, the maximum load, and the SNR of the measurement system.

Using open source accelerometer analysis to assess physical activity and sedentary behaviour in overweight and obese adults.

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Innerd, Paul; Harrison, Rory; Coulson, Morc

2018-04-23

Physical activity and sedentary behaviour are difficult to assess in overweight and obese adults. However, the use of open-source, raw accelerometer data analysis could overcome this. This study compared raw accelerometer and questionnaire-assessed moderate-to-vigorous physical activity (MVPA), walking and sedentary behaviour in normal, overweight and obese adults, and determined the effect of using different methods to categorise overweight and obesity, namely body mass index (BMI), bioelectrical impedance analysis (BIA) and waist-to-hip ratio (WHR). One hundred twenty adults, aged 24-60 years, wore a raw, tri-axial accelerometer (Actigraph GT3X+), for 3 days and completed a physical activity questionnaire (IPAQ-S). We used open-source accelerometer analyses to estimate MVPA, walking and sedentary behaviour from a single raw accelerometer signal. Accelerometer and questionnaire-assessed measures were compared in normal, overweight and obese adults categorised using BMI, BIA and WHR. Relationships between accelerometer and questionnaire-assessed MVPA (Rs = 0.30 to 0.48) and walking (Rs = 0.43 to 0.58) were stronger in normal and overweight groups whilst sedentary behaviour were modest (Rs = 0.22 to 0.38) in normal, overweight and obese groups. The use of WHR resulted in stronger agreement between the questionnaire and accelerometer than BMI and BIA. Finally, accelerometer data showed stronger associations with BMI, BIA and WHR (Rs = 0.40 to 0.77) than questionnaire data (Rs = 0.24 to 0.37). Open-source, raw accelerometer data analysis can be used to estimate MVPA, walking and sedentary behaviour from a single acceleration signal in normal, overweight and obese adults. Our data supports the use of WHR to categorise overweight and obese adults. This evidence helps researchers obtain more accurate measures of physical activity and sedentary behaviour in overweight and obese populations.

Diuretics prescribing in chronic kidney disease patients: physician assessment versus bioimpedence spectroscopy.

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Khan, Yusra Habib; Sarriff, Azmi; Adnan, Azreen Syazril; Khan, Amer Hayat; Mallhi, Tauqeer Hussain

2017-06-01

The relationship between hypertension and fluid overload in pre-dialysis CKD patients need to be elucidated. Current study aimed to find relationship between fluid overload and hypertension along with prescribed diuretic therapy using bioimpedance spectroscopy (BIS). A prospective observational study was conducted by inviting pre-dialysis CKD patients. Fluid overload was assessed by BIS. A total of 312 CKD patients with mean eGFR 24.5 ± 11.2 ml/min/1.73 m 2 were enrolled. Based on OH value ≥7 %, 135 (43.3 %) patients were hypervolemic while euvolemia was observed in 177 (56.7 %) patients. Patients were categorized in different regions of hydration reference plot (HRP) generated by BIS i.e., 5.1 % in region-N (normal BP and fluid status), 20.5 % in region I (hypertensive with severe fluid overload), 29.5 % in region I-II (hypertensive with mild fluid overload), 22 % in region II (hypertensive with normohydration), 10.2 % in region III (underhydration with normal/low BP) and 12.5 % in region IV (normal BP with severe fluid overload). A total of 144 (46 %) patients received diuretics on basis of physician assessment of BP and edema. Maximum diuretics 100 (69.4 %) were prescribed in patients belonging to regions I and I-II of HRP. Interestingly, a similar number of diuretic prescriptions were observed in region II (13 %) and region IV (12 %). Surprisingly, 7 (4.9 %) of patients in region III who were neither hypervolemic nor hypertensive were also prescribed with diuretics. BIS can aid clinicians to categorize CKD patients on basis of their fluid status and provide individualized pharmacotherapy to manage hypertensive CKD patients.

Feasibility of bioelectrical impedance analysis in persons with severe intellectual and visual disabilities

NARCIS (Netherlands)

Havinga-Top, Thamar; Waninge, Aly; van der Schans, Cees; Jager, Harriët

2015-01-01

Background: Body composition measurements provide importanti nformation about physical fitness and nutritional status. People with severe intellectual and visual disabilities (SIVD) have an increased risk for altered body composition. Bioelectrical impedance analysis (BIA) has been evidenced as a

Feasibility of bioelectrical impedance analysis in persons with severe intellectual and visual disabilities

NARCIS (Netherlands)

Havinga-Top, A. M.; Waninge, A.; van der Schans, C. P.; Jager-Wittenaar, H.

2015-01-01

Background: Body composition measurements provide important information about physical fitness and nutritional status. People with severe intellectual and visual disabilities (SIVD) have an increased risk for altered body composition. Bioelectrical impedance analysis (BIA) has been evidenced as a

Bioelectrical impedance analysis for diagnosing sarcopenia and cachexia: what are we really estimating?

Science.gov (United States)

Gonzalez, Maria Cristina; Heymsfield, Steven B

2017-04-01

As reference methods are not available for identifying low skeletal muscle mass in clinical practice, the European Group on Sarcopenia in Older People the Asian Working Group for Sarcopenia and the International Consensus for Cancer Cachexia guidelines accept bioelectrical impedance analysis (BIA) as an option for sarcopenia and cachexia assessment. Using different BIA equations, several components that represent 'muscularity' can be assessed. Total skeletal muscle mass or appendicular skeletal muscle mass normalized in relation to height (skeletal muscle mass index or appendicular skeletal muscle index, respectively) is the most common term used in the consensus. These terms are similar, but they should not be used as synonymous. Both terms can be used to define sarcopenia, but adequate equations and cut-off values should be used according to the studied population. However, there is a disagreement between the sarcopenia definition assessed by using BIA from the European Group on Sarcopenia in Older People and Cachexia Consensus, and this can lead to an overestimation of sarcopenia and, consequently, cachexia. An effort should be made to standardize the terminology employed by the Societies to define low muscularity and sarcopenia by using BIA. Future validation studies may show the need for specific cut-off values for each population using this method. © 2017 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders.

Estudo da degradação anaeróbia do efluente de indústrias de mobiliário

OpenAIRE

Caramelo, Marta Sofia Almeida

2012-01-01

O objeto deste trabalho está relacionado com a dependência atual de combustíveis fósseis para a produção de plástico e com as crescentes preocupações ambientais relativas à sua deposição no meio ambiente, pois são um material de difícil degradação. Estes problemas associados aos plásticos, têm resultado na investigação e desenvolvimento de materiais biopoliméricos que são de fácil biodegradação. Então este trabalho tem como objetivo principal, estudar a aplicabilidade da digestão anaeróbia...

Evaluation of body composition in COPD patients using multifrequency bioelectrical impedance analysis

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de Blasio F

2016-09-01

Full Text Available Francesca de Blasio,1 Francesco de Blasio,2,3 Giulia Miracco Berlingieri,2 Andrea Bianco,3,4 Marta La Greca,1 Frits M E Franssen,5 Luca Scalfi1 1Department of Public Health, Medical School, “Federico II” University of Naples, 2Respiratory Medicine and Pulmonary Rehabilitation Section, Clinic Center, Private Hospital, Naples, 3Department of Medicine and Health Sciences “V Tiberio”, University of Molise, Campobasso, 4Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples, Naples, Italy; 5Department of Research and Education, CIRO, Horn, the NetherlandsBackground: Multifrequency bioelectrical impedance analysis (MF-BIA is a technique that measures body impedance (Z at different frequencies (5, 10, 50, 100, and 250 kHz. Body composition may be estimated using empirical equations, which include BIA variables or, alternatively, raw BIA data may provide direct information on water distribution and muscle quality.Objectives: To compare raw MF-BIA data between COPD patients and controls and to study their relationship with respiratory and functional parameters in COPD patients.Methods: MF-BIA was performed (Human Im-Touch analyzer in 212 COPD patients and 115 age- and BMI-matched controls. Fat-free mass (FFM and fat mass were estimated from BIA data, and low- to high-frequency (5 kHz/250 kHz impedance ratio was calculated. Physical fitness, lung function and respiratory muscle strength were also assessed in COPD patients.Results: After adjusting for age, weight, and body mass index, FFM and the 5/250 impedance ratio were lower in COPD patients (P<0.001 and were negatively affected by disease severity. In both male and female patients, the 5/250 impedance ratio was significantly correlated mainly with age (r=−0.316 and r=−0.346, respectively. Patients with a 5/250 impedance ratio below median value had lower handgrip strength (P<0.001, 6-minute walk distance (P<0.005, respiratory muscle strength (P<0.005, forced

Nutritional assessment in patients with cirrhosis

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Sabrina Alves Fernandes

2012-03-01

Full Text Available CONTEXT: Malnutrition in cirrhotic patients with end-stage disease is common, and the degree of nutritional debilitation can play an important role in the pathogenesis of complications and cause a negative impact on prognosis. However, it involves difficulties and controversies regarding the identification of the best nutritional assessment method. OBJECTIVE: To identify a method that provides a safe and effective nutritional diagnosis. METHODS: Cross-sectional study with 129 cirrhotic patients. Anthropometric measurements, subjective global assessment, hand grip strength and bioelectrical impedance. RESULTS: Through phase angle of bioelectrical impedance analysis (BIA method, significant associations with Child-Pugh (P = 0.008, age group and gender were observed. The ROC (receiver operator characteristic curve was generated to determine the best cutoff point of the phase angle of cirrhotic patients, serving as one of the reference parameters for the nutritional assessment with bioimpedance in this study, considering the classification through Child-Pugh score as the reference standard for the clinical conditions of patients with cirrhosis. CONCLUSIONS: The assessment through bioelectrical impedance presented a statistically significant correlation with Child-Pugh score. The identification of phase angle of 5.44º is the new parameter suggested for the classification of the nutritional conditions of cirrhotic patients.

Frakcja lipidowa i białkowa nasion konopi siewnych (C. sativa L. oraz jej korzystny wpływ na zdrowie człowieka = Lipid and protein fraction of hemp seed (C. sativa L. and its beneficial influence on human health

Directory of Open Access Journals (Sweden)

Grzegorz Dąbrowski

2016-09-01

  Abstrakt Wprowadzenie i cel pracy: Konopie siewne wykorzystywane są od tysięcy lat do produkcji włókien oraz oleju z nasion. W ostatnim czasie nasiona tej rośliny wykorzystuje się także do produkcji izolatów i hydrolizatów białek. Celem niniejszej pracy jest opisanie składu frakcji tłuszczowej i białkowej nasion konopi siewnych oraz potencjału zdrowotnego oleju oraz izolatów i hydrolizatów białkowych pochodzących z tego surowca. Skrócony opis stanu wiedzy: Nasiona konopi są bogatym źródłem oleju oraz białka. Skład oleju jest korzystny z żywieniowego punktu widzenia z uwagi na duży udział niezbędnych nienasyconych kwasów tłuszczowych (NNKT oraz korzystne proporcje kwasów n-6/n-3. Olej konopny zawiera także duże ilości związków bioaktywnych, takich jak fitosterole, karotenoidy, polifenole i tokoferole. Białko konopi cechuje się dobrym składem aminokwasów oraz jest źródłem bioaktywnych peptydów o działaniu antyoksydacyjnym. Podsumowanie: Ze względu na zawartość oleju o korzystnym składzie kwasów tłuszczowych i wartościowego białka, nasiona konopi powinny być coraz częściej wprowadzane do codziennej diety. Słowa kluczowe: konopie siewne, NNKT, bioaktywne peptydy, tokoferole, fitosterole, polifenole, karotenoidy   Abstract Introduction and purpose: Hemp are used for thousands of years to obtain the fiber and seed oil. Recently, the hemp seeds are also used for the production of protein hydrolysates and isolates. The aim of this study is to describe the composition of the fat and protein fractions. In addition health benefits of the consumption of the oil  and protein hydrolysates and isolates will be described. Brief description of the state of the knoweledge: Hemp seeds are a rich source of oil and protein. The oil composition is beneficial from a nutritional point of view due to the high content of essential fatty acids (EFAs in the optimal ratio of n-6 / n-3. Hemp oil also contains large amounts of a

A current-excited triple-time-voltage oversampling method for bio-impedance model for cost-efficient circuit system.

Science.gov (United States)

Yan Hong; Yong Wang; Wang Ling Goh; Yuan Gao; Lei Yao

2015-08-01

This paper presents a mathematic method and a cost-efficient circuit to measure the value of each component of the bio-impedance model at electrode-electrolyte interface. The proposed current excited triple-time-voltage oversampling (TTVO) method deduces the component values by solving triple simultaneous electric equation (TSEE) at different time nodes during a current excitation, which are the voltage functions of time. The proposed triple simultaneous electric equations (TSEEs) allows random selections of the time nodes, hence numerous solutions can be obtained during a single current excitation. Following that, the oversampling approach is engaged by averaging all solutions of multiple TSEEs acquired after a single current excitation, which increases the practical measurement accuracy through the improvement of the signal-to-noise ratio (SNR). In addition, a print circuit board (PCB) that consists a switched current exciter and an analog-to-digital converter (ADC) is designed for signal acquisition. This presents a great cost reduction when compared against other instrument-based measurement data reported [1]. Through testing, the measured values of this work is proven to be in superb agreements on the true component values of the electrode-electrolyte interface model. This work is most suited and also useful for biological and biomedical applications, to perform tasks such as stimulations, recordings, impedance characterizations, etc.

Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis

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M. V. Konovalova

2014-07-01

Full Text Available The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years and of age-matched healthy controls (n = 1,500 show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell mass in fat-free mass. Malnutrition, judged from the prevalence of obesity and low phase angle, was observed in 52.7 % of our patients reaching a maximum of 76.8 % in a subgroup of children with CNS tumors. In view of known association that exists between malnutrition and reduced tolerance to chemotherapy, increased susceptibility to infections and adverse outcomes rate, we recommend using bioimpedance analysis in remission of childhood cancers in order to monitoring and timely correction of nutritional state as well as for prevention of delayed cardiovascular risks.

Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis

Directory of Open Access Journals (Sweden)

M. V. Konovalova

2012-01-01

Full Text Available The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years and of age-matched healthy controls (n = 1,500 show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell mass in fat-free mass. Malnutrition, judged from the prevalence of obesity and low phase angle, was observed in 52.7 % of our patients reaching a maximum of 76.8 % in a subgroup of children with CNS tumors. In view of known association that exists between malnutrition and reduced tolerance to chemotherapy, increased susceptibility to infections and adverse outcomes rate, we recommend using bioimpedance analysis in remission of childhood cancers in order to monitoring and timely correction of nutritional state as well as for prevention of delayed cardiovascular risks.

Feasibility of bioelectrical impedance analysis in persons with severe intellectual and visual disabilities.

Science.gov (United States)

Havinga-Top, A M; Waninge, A; van der Schans, C P; Jager-Wittenaar, H

2015-12-01

Body composition measurements provide important information about physical fitness and nutritional status. People with severe intellectual and visual disabilities (SIVD) have an increased risk for altered body composition. Bioelectrical impedance analysis (BIA) has been evidenced as a reliable and non-invasive method to asses body composition in healthy persons and various patient populations; however, currently, there is no feasible method available to determine body composition in people with SIVD. In this study, therefore, we aimed to assess the feasibility of BIA measurements in persons with SIVD. In 33 participants with SIVD and Gross Motor Functioning Classification System (GMFCS) Scale I, II, III, or IV, two BIA measurements were sequentially performed employing Resistance and Reactance in Ohm and fat-free mass (FFM) in kg as outcome variables, utilizing the Bodystat(®) QuadScan 4000. Feasibility was considered sufficient if ≥ 80% of the first measurement was performed successfully. Agreement between two repeated measurements was determined by using the paired t-test and Intraclass Correlation Coefficient (ICC; two way random, absolute agreement). Bland-Altman analyses were utilized to determine limits of agreement (LOAs) and systematic error. Agreement was considered acceptable if LOAs were feasible in persons with SIVD. Although these results require confirmation in a more extensive sample of persons with SIVD, the findings of this study are an important first step in the assessment of applicability of BIA measurements for non-invasive monitoring of physical fitness and nutritional status of persons with SIVD. Copyright © 2015 Elsevier Ltd. All rights reserved.

Association of Body Composition with Curve Severity in Children and Adolescents with Idiopathic Scoliosis (IS

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Edyta Matusik

2016-01-01

Full Text Available The link between scoliotic deformity and body composition assessed with bioimpedance (BIA has not been well researched. The objective of this study was to correlate the extent of scoliotic-curve severity with the anthropometrical status of patients with idiopathic scoliosis (IS based on standard anthropometric measurements and BIA. The study encompassed 279 IS patients (224 girls/55 boys, aged 14.21 ± 2.75 years. Scoliotic curve severity assessed by Cobb’s angle was categorized as moderate (10°–39° or severe (≥40°. Corrected height, weight, waist and hip circumferences were measured and body mass index (BMI, corrected height z-score, BMI Z-score, waist/height ratio (WHtR and waist/hip ratio (WHR were calculated for the entire group. Body composition parameters: fat mass (FAT, fat-free mass (FFM and predicted muscle mass (PMM were determined using a bioelectrical impedance analyzer. The mean Cobb angle was 19.96° ± 7.92° in the moderate group and 52.36° ± 12.54° in the severe group. The corrected body heights, body weights and BMIs were significantly higher in the severe IS group than in the moderate group (p < 0.05. Significantly higher FAT and lower FFM and PMM were observed in the severe IS group (p < 0.05. The corrected heights and weights were significantly higher in patients with severe IS and normal weight (p < 0.01. Normal and overweight patients with a severe IS had significantly higher adiposity levels assessed by FAT, FFM and PMM for normal and BMI, BMI z-score, WHtR, FAT and PMM for overweight, respectively. Overweight IS patients were significantly younger and taller than underweight and normal weight patients. The scoliotic curve severity is significantly related to the degree of adiposity in IS patients. BMI z-score, WHtR and BIA seem to be useful tools for determining baseline anthropometric characteristics of IS children.

Synanthropization of dendroflora near main roads in Białystok (NE Poland

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Łaska Grażyna

2015-06-01

Full Text Available The aim of the study was to analyze the species composition of the dendroflora near four main roads in the city of Białystok, taking into regard their geographical and historical origin. The wildlife inventory was conducted in the vegetation season of 2011. The inventory revealed presence of a total of 837 trees and bushes representing 36 species and 18 families. The most abundant trees were those from the family Aceraceae (63.8%, while the most abundant bushes were those representing Rosaceae (48.9%. The contribution of native species (65.7% was found to be about twice as high as that of alien ones (34.3%. The dominant species among the native trees was Acer platanoides L., while the principal bush species was Crataegus monogyna Jacq. The alien tree species were most commonly represented by Acer negundo L., and bushes - by Ligustrum vulgare L. Spontaneously settled trees and bushes were clearly dominant (59.9% over those originating from plantations (40.1%. Among the native species of local origin, the prevailing species were synanthropic spontaneophytes (52%, including Acer platanoides and Tilia cordata Mill. Anthropophytes were more abundantly represented by diaphytes (22.7%, followed by kenophytes (10.4%. The most abundant species among diaphytes was Ligustrum vulgare, and among kenophytes - Acer negundo.

Estimation of total body water by bioelectrical impedance analysis

International Nuclear Information System (INIS)

Kushner, R.F.; Schoeller, D.A.

1986-01-01

Total body water (TBW) measured by bioelectrical impedance analysis (BIA) was directly compared with deuterium-isotope dilution in a total of 58 subjects. First, sex-specific and group equations were developed by multiple regression analysis in (10 each) obese and nonobese men and women. Height/resistive impedance was the most significant variable used to predict deuterium-dilution space (D2O-TBW) and, combined with weight, yielded R = 0.99 and SE of estimate = 1.75 L. Equations predicted D2O-TBW equally well for obese and nonobese subjects. Second, the equations were prospectively tested in a heterogeneous group of 6 males and 12 females. Sex-specific equations predicted D2O-TBW with good correlation coefficients (0.96 and 0.93), total error (2.34 and 2.89 L), and a small difference between mean predicted and measured D2O-TBW (-1.4 +/- 2.05 and -0.48 +/- 2.83 L). BIA predicts D2O-TBW more accurately than weight, height, and/or age. A larger population is required to validate the applicability of our equations

Budget impact analysis of pemetrexed introduction: case study from a teaching hospital perspective, Thailand.

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Chanjaruporn, Farsai; Roughead, Elizabeth E; Sooksriwong, Cha-oncin; Kaojarern, Sming

2011-09-01

Thailand does not currently require Budget Impact Analysis (BIA) assessment. The present study aimed to estimate the annual drug cost and the incremental impact on the hospital pharmaceutical budget of the introduction of pemetrexed to a Thai teaching hospital. The budget impact model was conducted in accordance with the Guidelines for preparing submissions to the Pharmaceutical Benefits Advisory Committee (PBAC). The model variables consisted of number of patients, growth rate of lung cancer, uptake rate of pemetrexed over time, unit prices of drugs, and the length and cost of treatment. Sensitivity analysis was performed to determine changes in budgetary impact due to variation of parameters or assumptions in the model. The introduction of pemetrexed was estimated to cause considerable costs for the teaching hospital. In the base-case analysis, the incremental costs were estimated at 8,553,984 Baht in the first year increasing to 12, 118, 144 Baht, 17,820,800 Baht and 17,820,800 Baht in the following years. The 4-year net budgetary impact was 20,154,480 Baht or approximately 127,560 Baht per patient. Sensitivity analyses found that number of treatment cycles andproportion of patients assumed to be treated with pemetrexed were the two most important influencing factors in the model. New costly innovative interventions should be evaluated using the BIA model to determine whether they are affordable. The Thai government should consider requiring the BIA study as one of the requirements for drug submission to assist in the determination of listing and subsidizing decision for medicines.

A guerra como instrumento do poder presidencial nos EUA: o caso da intervenção na Líbia

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Cláudio Júnior Damin

2012-08-01

Full Text Available Analisa-se a decisão da participação dos EUA na intervenção militar na Líbia em 2011. O objetivo central é posicionar a decisão de Barack Obama de utilizar as forças armadas como um exercício dos poderes de guerra do presidente enquanto comandante-em-chefe e como executor de deliberações de órgãos multilaterais internacionais.   We analyze the decision of U.S. participation in military intervention in Libya (2011. The main objective is to position Barack Obama's decision to use the military as an exercise of war powers of the president as commander in chief and as a doer of the deliberations of international multilateral agencies.

The comparative evaluation of patients′ body dry weight under hemodialysis using two methods: Bioelectrical impedance analysis and conventional method

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Neda Alijanian

2012-01-01

Full Text Available Background: Dry weight (DW is an important concept related to patients undergoing hemodialysis. Conventional method seems to be time consuming and operator dependent. Bio impedance analysis (BIA is a new and simple method reported to be an accurate way for estimating DW. In this study, we aimed to compare the conventional estimation of DW with measuring DW by BIA. Materials and Methods: This study involved 130 uremic patients, performed in Isfahan, Iran. DW was calculated by both conventional (CDW and BIA (BIADW method and results were compared based on different grouping factors including sex, underlying cause of renal failure (RF (diabetic RF and non-diabetic RF, body mass index (BMI status, and sessions of hemodialysis. We also calculated the difference between DWs of 2 methods (DW diff = CDW-BIADW. Results: The mean of BIADW was significantly lower than CDW (57.20 ± 1.82 vs 59.36 ± 1.77, P value < 0.001. After grouping cases according to the underlying cause, BMI, sex, and dialysis sessions BIADW was significantly lower than CDW. Conclusion: Based on the combination of problems with CDW measurement which are corrected by BIA, and more clinical reliability of CDW, we concluded that although conventional method is a time-consuming and operator-dependent way to assess DW, DW could be estimated by combining both of these methods by finding the mathematic correlation between these methods.

A comparison of three methods to assess body composition.

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Tewari, Nilanjana; Awad, Sherif; Macdonald, Ian A; Lobo, Dileep N

2018-03-01

The aim of this study was to compare the accuracy of measurements of body composition made using dual x-ray absorptiometry (DXA), analysis of computed tomography (CT) scans at the L3 vertebral level, and bioelectrical impedance analysis (BIA). DXA, CT, and BIA were performed in 47 patients recruited from two clinical trials investigating metabolic changes associated with major abdominal surgery or neoadjuvant chemotherapy for esophagogastric cancer. DXA was performed the week before surgery and before and after commencement of neoadjuvant chemotherapy. BIA was performed at the same time points and used with standard equations to calculate fat-free mass (FFM). Analysis of CT scans performed within 3 mo of the study was used to estimate FFM and fat mass (FM). There was good correlation between FM on DXA and CT (r 2  = 0.6632; P FFM on DXA and CT (r 2  = 0.7634; P FFM on DXA and BIA (r 2  = 0.6275; P FFM on CT and BIA also was significant (r 2  = 0.2742; P FFM on DXA and CT, average bias was -0.1477, with LOA of -8.621 to 8.325. For FFM on DXA and BIA, average bias was -3.792, with LOA of -15.52 to 7.936. For FFM on CT and BIA, average bias was -2.661, with LOA of -22.71 to 17.39. Although a systematic error underestimating FFM was demonstrated with BIA, it may be a useful modality to quantify body composition in the clinical situation. Copyright © 2017 Elsevier Inc. All rights reserved.

Bioimpedance Spectroscopy for Assessment of Volume Status in Patients before and after General Anaesthesia

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Ernstbrunner, Matthäus; Kostner, Lisa; Kimberger, Oliver; Wabel, Peter; Säemann, Marcus; Markstaller, Klaus; Fleischmann, Edith; Kabon, Barbara; Hecking, Manfred

2014-01-01

Background Technically assisted assessment of volume status before surgery may be useful to direct intraoperative fluid administration. We therefore tested a recently developed whole-body bioimpedance spectroscopy device to determine pre- to postoperative fluid distribution. Methods Using a three-compartment physiologic tissue model, the body composition monitor (BCM, Fresenius Medical Care, Germany) measures total body fluid volume, extracellular volume, intracellular volume and fluid overload as surplus or deficit of ‘normal’ extracellular volume. BCM-measurements were performed before and after standardized general anaesthesia for gynaecological procedures (laparotomies, laparoscopies and vaginal surgeries). BCM results were blinded to the attending anaesthesiologist and data analysed using the 2-sided, paired Student’s t-test and multiple linear regression. Results In 71 females aged 45±15 years with body weight 67±13 kg and duration of anaesthesia 154±68 min, pre- to postoperative fluid overload increased from −0.7±1.1 L to 0.1±1.0 L, corresponding to −5.1±7.5% and 0.8±6.7% of normal extracellular volume, respectively (both p<0.001), after patients had received 1.9±0.9 L intravenous crystalloid fluid. Perioperative urinary excretion was 0.4±0.3 L. The increase in extracellular volume was paralleled by an increase in total body fluid volume, while intracellular volume increased only slightly and without reaching statistical significance (p = 0.15). Net perioperative fluid balance (administered fluid volume minus urinary excretion) was significantly associated with change in extracellular volume (r2 = 0.65), but was not associated with change in intracellular volume (r2 = 0.01). Conclusions Routine intraoperative fluid administration results in a significant, and clinically meaningful increase in the extracellular compartment. BCM-measurements yielded plausible results and may become useful to guide intraoperative fluid therapy in

Moist air state above counterflow wet-cooling tower fill based on Merkel, generalised Merkel and Klimanek & Białecky models

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Hyhlík, Tomáš

2017-09-01

The article deals with an evaluation of moist air state above counterflow wet-cooling tower fill. The results based on Klimanek & Białecky model are compared with results of Merkel model and generalised Merkel model. Based on the numerical simulation it is shown that temperature is predicted correctly by using generalised Merkel model in the case of saturated or super-saturated air above the fill, but the temperature is underpredicted in the case of unsaturated moist air above the fill. The classical Merkel model always under predicts temperature above the fill. The density of moist air above the fill, which is calculated using generalised Merkel model, is strongly over predicted in the case of unsaturated moist air above the fill.

Lipid and moisture content modeling of amphidromous Dolly Varden using bioelectrical impedance analysis

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Stolarski, J.T.; Margraf, F.J.; Carlson, J.G.; Sutton, T.M.

2014-01-01

The physiological well-being or condition of fish is most commonly estimated from aspects of individual morphology. However, these metrics may be only weakly correlated with nutritional reserves stored as lipid, the primary form of accumulated energy in fish. We constructed and evaluated bioelectrical impedance analysis (BIA) models as an alternative method of assessing condition in amphidromous Dolly Varden Salvelinus malma collected from nearshore estuarine and lotic habitats of the Alaskan Arctic. Data on electrical resistance and reactance were collected from the lateral and ventral surfaces of 192 fish, and whole-body percent lipid and moisture content were determined using standard laboratory methods. Significant inverse relationships between temperature and resistance and reactance prompted the standardization of these data to a constant temperature using corrective equations developed herein. No significant differences in resistance or reactance were detected among spawning and nonspawning females after accounting for covariates, suggesting that electrical pathways do not intersect the gonads. Best-fit BIA models incorporating electrical variables calculated from the lateral and ventral surfaces produced the strongest associations between observed and model-predicted estimates of proximate content. These models explained between 6% and 20% more of the variability in laboratory-derived estimates of proximate content than models developed from single-surface BIA data and 32% more than models containing only length and weight data. While additional research is required to address the potential effects of methodological variation, bioelectrical impedance analysis shows promise as a way to provide high-quality, minimally invasive estimates of Dolly Varden lipid or moisture content in the field with only small increases in handling time.

Making the invisible visible: bioelectrical impedance analysis demonstrates unfavourable body composition in rheumatoid arthritis patients in clinical practice.

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Konijn, N P C; van Tuyl, L H D; Bultink, I E M; Lems, W F; Earthman, C P; van Bokhorst-de van der Schueren, M A E

2014-01-01

To examine differences between the assessment of body composition by body mass index (BMI) and bioelectrical impedance analysis (BIA) in patients with rheumatoid arthritis (RA). The body composition of RA patients was assessed during their visit to the outpatient department of a Dutch academic hospital using BMI, fat-free mass index (FFMI), and fat mass index (FMI). FFMI and FMI were determined by single-frequency BIA. Sixty-five consecutive RA patients (83% women, mean age 58 years, median disease duration 7 years) with moderately active disease [mean Disease Activity Score using 28 joint counts (DAS28) = 3.40; mean Rheumatoid Arthritis Disease Activity Index (RADAI) score = 3.49] and moderate disability [mean Health Assessment Questionnaire (HAQ) score = 0.87] were included. Based on BMI, 2% of our study population were underweight, 45% had a healthy body composition, and 54% were overweight or obese. Based on BIA, 18% of the patients showed a low FFMI and 74% had a high or very high FMI. Low FFMI was found in 44% of the women with a normal BMI, and high FMI was found in 40% of the women and 75% of the men with a normal BMI. A high frequency of unfavourable body composition, predominantly reduced FFMI and elevated FMI, was found in a cohort of RA patients with moderately active disease, turning BMI into an unreliable method for assessment of body composition in RA. BIA, however, might be the preferred method to assess FFMI and FMI in RA patients in clinical practice, as it is easy to use and relatively inexpensive.

Development of a single-frequency bioimpedance prediction equation for fat-free mass in an adult Indigenous Australian population.

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Hughes, J T; Maple-Brown, L J; Piers, L S; Meerkin, J; O'Dea, K; Ward, L C

2015-01-01

To describe the development of a single-frequency bioimpedance prediction equation for fat-free mass (FFM) suitable for adult Aboriginal and Torres Strait Islander peoples with and without diabetes or indicators of chronic kidney disease (CKD). FFM was measured by whole-body dual-energy X-ray absorptiometry in 147 adult Indigenous Australians. Height, weight, body circumference and resistance were also measured. Adults with and without diabetes and indicators of CKD were examined. A random split sample with internal cross-validation approach was used to predict and subsequently validate FFM using resistance, height, weight, age and gender against measured FFM. Among 147 adults with a median body mass index of 31 kg/m(2), the final model of FFM was FFM (kg)=0.432 (height, cm(2)/resistance, ohm)-0.086 (age, years)+0.269 (weight, kg)-6.422 (if female)+16.429. Adjusted R(2) was 0.94 and the root mean square error was 3.33 kg. The concordance was high (rc=0.97) between measured and predicted FFM across a wide range of FFM (31-85 kg). In the context of the high burden of diabetes and CKD among adult Indigenous Australians, this new equation for FFM was both accurate and precise and based on easily acquired variables (height, weight, age, gender and resistance) among a heterogeneous adult cohort.

Validity of bioelectrical impedance analysis to assess fat−free mass in head and neck cancer patients : an exploratory study

NARCIS (Netherlands)

Jager-Wittenaar, Harriët; Dijkstra, Pieter; Earthman, Carrie; Krijnen, Wim; Langendijk, Johannes A.; van der Laan, Bernard; Pruim, Jan; Roodenburg, Jan

2013-01-01

Assessment and monitoring of fat-free mass (FFM) is of clinical importance, because FFM is reflective of body cell mass, the total mass of protein-rich, metabolically active cells which is affected during malnutrition and therefore related to clinical outcome. Bioelectrical impedance analysis (BIA)

[Comparison BMC assessed by dual-energy X-ray absorptiometry and multi-frequency bioelectrical impedance in Chinese overweight and obesity adults].

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Wang, Zhenghe; Fu, Lianguo; Yang, Yide; Wang, Shuo; Ma, Jun

2016-05-01

To compare consistency of Body Mineral Content (BMC, kg) assessed by Multi-frequency Bioelectrical Impedance Analysis ( MF-BIA) and Dual Energy X-ray Absorptiometry (DXA) measurement, providing evidence for MF-BIA accurate application in Chinese overweight/obese adults. A total of 1323 overweight/obesity adults aged 22-55 years were recruited voluntarily. All the subjects received the measurement of BMC both using MF-BIA and DXA. To evaluate the agreement of BMC measured by MF-BIA and DXA using interclass correlation coefficients (ICC), then establish correction prediction models. The mean difference of BMC between two methods was significant different with 0, overweight male subgroup was 0.28 kg, and 0.38 kg for obesity male, 0.24 kg for overweight female and 0.36 kg for obesity female, respectively (P BMC between MF-BIA and DXA measurement were statistically significant in all subgroups (P BMC (DXA method) = -0.297 + 1.005 x BMC (MF-BIA method). Obese male population: BMC (DXA method) =0.302 + 0.799 x BMC (MF-BIA method). Overweight female groups: BMC (DXA method) = 0.780 + 0.598 x BMC (MF-BIA method). Obese female group: BMC (DXA method) = 0.755 + 0.597 x BMC (MF-BIA method). Upon examination, correction prediction models were better. Co The correlation and agreement of BMC measured by BIA and DXA are weak in Chinese overweight/obese adults. Therefore, consideration should be given to BMC measured by BIA method in Chinese overweight/obese adults. It should be corrected or adjusted to reduce errors compared with DXA method.

Vaccines are different: A systematic review of budget impact analyses of vaccines.

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Loze, Priscilla Magalhaes; Nasciben, Luciana Bertholim; Sartori, Ana Marli Christovam; Itria, Alexander; Novaes, Hillegonda Maria Dutilh; de Soárez, Patrícia Coelho

2017-05-15

Several countries require manufacturers to present a budget impact analysis (BIA), together with a cost-effectiveness analysis, to support national funding requests. However, guidelines for conducting BIA of vaccines are scarce. To analyze the methodological approaches used in published budget impact analysis (BIA) of vaccines, discussing specific methodological issues related to vaccines. This systematic review of the literature on BIA of vaccines was carried out in accordance with the Centre for Reviews and Dissemination - CRD guidelines. We searched multiple databases: MedLine, Embase, Biblioteca Virtual de Saúde (BVS), Cochrane Library, DARE Database, NHS Economic Evaluation Database (NHS EED), HTA Database (via Centre for Reviews and Dissemination - CRD), and grey literature. Two researchers, working independently, selected the studies and extracted the data. The methodology quality of individual studies was assessed using the ISPOR 2012 Budget Impact Analysis Good Practice II Task Force. A qualitative narrative synthesis was conducted. Twenty-two studies were reviewed. The most frequently evaluated vaccines were pneumococcal (41%), influenza (23%) and rotavirus (18%). The target population was stated in 21 studies (95%) and the perspective was clear in 20 (91%). Only 36% reported the calculations used to complete the BIA, 27% informed the total and disaggregated costs for each time period, and 9% showed the change in resource use for each time period. More than half of the studies (55%, n=12) reported less than 50% of the items recommended in the checklist. The production of BIA of vaccines has increased from 2009. The report of the methodological steps was unsatisfactory, making it difficult to assess the validity of the results presented. Vaccines specific issues should be discussed in international guidelines for BIA of vaccines, to improve the quality of the studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

Feasibility and acceptability of a self-measurement using a portable bioelectrical impedance analysis, by the patient with chronic heart failure, in acute decompensated heart failure.

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Huguel, Benjamin; Vaugrenard, Thibaud; Saby, Ludivine; Benhamou, Lionel; Arméro, Sébastien; Camilleri, Élise; Langar, Aida; Alitta, Quentin; Grino, Michel; Retornaz, Frédérique

2018-06-01

Chronic heart failure (CHF) is a major public health matter. Mainly affecting the elderly, it is responsible for a high rate of hospitalization due to the frequency of acute heart failure (ADHF). This represents a disabling pathology for the patient and very costly for the health care system. Our study is designed to assess a connected and portable bioelectrical impedance analysis (BIA) that could reduce these hospitalizations by preventing early ADHF. This prospective study included patients hospitalized in cardiology for ADHF. Patients achieved 3 self-measurements using the BIA during their hospitalization and answered a questionnaire evaluating the acceptability of this self-measurement. The results of these measures were compared with the clinical, biological and echocardiographic criteria of patients at the same time. Twenty-three patients were included, the self-measurement during the overall duration of the hospitalization was conducted autonomously by more than 80% of the patients. The acceptability (90%) for the use of the portable BIA was excellent. Some correlations were statistically significant, such as the total water difference to the weight difference (p=0.001). There were common trends between the variation of impedance analysis measures and other evaluation criteria. The feasibility and acceptability of a self-measurement of bioelectrical impedance analysis by the patient in AHF opens up major prospects in the management of monitoring patients in CHF. The interest of this tool is the prevention of ADHF leading to hospitalization or re-hospitalizations now requires to be presented by new studies.

Comparison of resting energy equations and total energy expenditure in haemodialysis patients and body composition measured by multi-frequency bioimpedance.

Science.gov (United States)

Oliveira, Ben; Sridharan, Sivakumar; Farrington, Ken; Davenport, Andrew

2017-07-13

Waste products of metabolism are retained in haemodialysis (HD) patients. Cellular metabolism generates energy, and patients with greater energy expenditure may therefore require more dialysis. To determine the amount of dialysis required, equations estimating resting and total energy expenditure (REE,TEE) are required. We compared estimates of REE in HD patients using established equations with a novel equation recently validated in HD patients (HD equation). TEE was derived from REE (HD equation) and estimates of physical activity obtained by questionnaire. REE and TEE relationships with bioimpedance measured body composition were then determined. We studied 317 HD patients; 195 males (61.5%), 123 diabetic (38.9%), mean age 65.0 ± 15.3 and weight 73.1 ± 16.8 kg. REE from HD Equation was 1509 ± 241 kcal/day, which was greater than for Mifflin St Joer 1384 ± 259, Harris-Benedict 1437 ± 244, Katch-McArdle 1345 ± 232 (all p employment (β 406.5, p appearance (β 2.7, p = 0.015), and negatively with age (β -7.9, p appearance, lower co-morbidity, age, and dialysis vintage, and the employed. More metabolically active patients may require greater dialytic clearances. This article is protected by copyright. All rights reserved.

The occurrence of parasitic arthropods in two groups of European bison in the Białowieza primeval forest.

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Izdebska, J N

2001-01-01

Within 1992-2000, a total of 181 Białowieza Forest bison were examined from two winter herds. Twelf parasitic arthropod species were observed, a high infestation being typical of Demodex bisonianius, Chorioptes bovis, Ixodes ricinus, Dermacentor reticulatus, and Bisonicola sedecimdecembrii. The infestation in section 422 herd being higher for B. sedecimdecembrii, I. ricinus, D. reticulatus, Ch. bovis. D. bisonianus was slightly more prevalent in the section 391 herd, the intensity being, however, lower than that in the other herd. Among the remaining arthropods found in the Bialowieza Forest European bison, some Lipoptena cervi occurred in both herds, Demodex sp. and Sarcoptes scabiei were recorded only in the section 422 herd, Ixodes persulcatus was present only in the section 391 bison and those kept in the reservation, while D. bovis, Psoroptes ovis, and Melophagus ovinus were found in the reserve bison only. In the present study, the largest differences in the extent of infestation involved the hair-dwelling arthropods (B. sedecimdecembrii, I. rixinus).

Body composition analysis and adipocytokine concentrations in haemodialysis patients: abdominal fat gain as an additional cardiovascular risk factor.

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González, Elena; Díez, Juan J; Pérez Torres, Almudena; Bajo, María Auxiliadora; Del Peso, Gloria; Sánchez-Villanueva, Rafael; Grande, Cristina; Rodríguez, Olaia; Coronado, Mónica; Gómez Candela, Carmen; Díaz-Almirón, Mariana; Iglesias, Pedro; Selgas, Rafael

Abdominal fat and its increment over time in particular has become a cardiovascular risk factor in uraemic patients. To analyse changes in abdominal fat in haemodialysis patients over one year and study their possible correlation with the variation in adipocytokine serum levels. As a secondary objective, we tried to validate the data obtained by bioelectrical impedance analysis (BIA) with data obtained by dual X-ray absorptiometry (DXA). A prospective one-year study was performed in 18 patients on haemodialysis (HD). In each patient, body composition by BIA and DXA was estimated at baseline and after one year. Several adipocytokine and biochemical parameters were determined. A significant increase in phase angle [4.8° (4.1-5.6) vs. 5.2° (4.4-5.8), Pfat measured by DXA [1.00 (0.80-1.26) vs. 1.02 (0.91-1.30), Pfat mass measured by BIA, as well as the abdominal fat percentage estimated by DXA, was found (Pfat mass over time, especially in the abdomen, evidenced by an increased A/G ratio. These findings might explain the increased cardiovascular risk in these patients. Copyright © 2016 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.

Participation and Protected Areas Governance: the Impact of Changing Influence of Local Authorities on the Conservation of the Białowieża Primeval Forest, Poland

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Krzysztof Niedziałkowski

2012-03-01

Full Text Available According to the new conservation paradigm, protected areas should contribute to the socioeconomic development of host communities, and the latter ought to be included in participatory decision making concerning these areas. However, the understanding of participation is ambiguous and there are at least three major approaches, which may have different impacts on the governance of protected areas. We examine the case of the Białowieża Primeval Forest in order to trace the effectiveness of changing modes of participation as well as to discuss the limitations and problems of public participation. Between 1918 and 2010, the role of local authorities changed from no influence to limited control over decision making regarding designation and enlargement of the Białowieża National Park (BNP. As a result of these changes, attempts to enlarge the BNP over the whole forest were undermined. The evidence shows that power relations and instrumental reasons constituted the main drivers of the changing participation pattern with deliberative rationale lacking. As a result, the conservation goals were only partially achieved. We argue that when interests are clearly conflicting and win-win solutions are difficult to reach, room for constructive participation may be limited. In these circumstances, public involvement may turn into yet another venue for a power play between actors with vested interests, without bringing gains in legitimacy or new policy options. This is especially the case for countries with a relatively short democratic record where the government lacks the consistency and capacity to steer the process over the longer term.

The association between bioimpedance analysis and quality of life in pre-dialysis stage 5 chronic kidney disease, hemodialysis and peritoneal dialysis patients.

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Yongsiri, Somchai; Thammakumpee, Jiranuch; Prongnamchai, Suriya; Dinchuthai, Pakaphan; Chueansuwan, Rachaneeporn; Tangjaturonrasme, Siriporn; Chaivanit, Pechngam

2014-03-01

Protein-energy wasting is a significant problem in End stage renal disease (ESRD) patients. Furthermore, it compromises the patient's Quality of life (QOL). Multifrequency Bioimpedance Spectroscopy (BIS) is a validated method to assess body composition in dialysis patients. There has been no data on the relationship between body composition and QOL in ESRD patients who were treated with different modalities. To explore the association between body composition as assessed by BIS and QOL in ESRD patients who received different treatment modalities. The present study is a cross sectional, descriptive analytic study of the association between QOL and BIS in ESRD patients in Burapha University, Chonburi, Thailand. QOL was assessed by WHOQOL-BREF questionnaire, body composition was measured by BIS technique. The difference between groups was tested by one-way ANOVA test, relationship between groups was tested with Pearson correlation test. Eighteen predialysis-CKD5, 26 peritoneal dialysis (PD), and 34 hemodialysis (HD) patients were included in the present study. All PD patients had weekly Kt/V > or = 1.7 per week and all HD patients had weekly Kt/V > or = 3.6 per week. There were no statistically difference in baseline characteristics including Charlson comorbidity index, dietary intake, BMI, and blood pressure between groups. Mean QOL scores in each group were in the middle range and not significantly difference. PD patients had more over hydration when compare to HD patients (16.18 +/- 11.24 vs. 2.36 +/- 11.07 %OH/ECW p < 0.0001). There were inversed correlation between overhydration and physical health in HD patients (r = -0.372, p = 0.033) but not in PD and CKD5 patients. CKD5 patients had more lean tissue index (LTI) than PD and HD patients (LTI = 14.34 +/- 3.13, 12.26 +/- 3.65, 11.48 +/- 3.48 kg/m2 respectively, p = 0.023). There were correlation between LTI and overall QOL in CKD5 (r = 0.690, p = 0.002) and PD patients (r = 0.498, p = 0.010). In HD patients, LTI

Total and Segmental Body Composition Examination in Collegiate Football Players Using Multifrequency Bioelectrical Impedance Analysis and Dual X-ray Absorptiometry.

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Raymond, Christiana J; Dengel, Donald R; Bosch, Tyler A

2018-03-01

Raymond, CJ, Dengel, DR, and Bosch, TA. Total and segmental body composition examination in collegiate football players using multifrequency bioelectrical impedance analysis and dual X-ray absorptiometry. J Strength Cond Res 32(3): 772-782, 2018-The current study examined the influence of player position on the agreement between multifrequency bioelectrical impedance analysis (MfBIA) and dual X-ray absorptiometry (DXA) when assessing total and segmental percent body fat (BF%), fat mass (FM), and fat-free mass (FFM) in National Collegiate Athletic Association Division I collegiate football athletes. Forty-four male collegiate athletes (age = 19 ± 1 year; height = 1.9 ± 1.0 m; and body mass = 106.4 ± 18.8 kg) participated. Player positions included: offensive linemen (OL; n = 7), tight ends (TE; n = 4), wide receivers (WR; n = 9), defensive linemen (DL; n = 6), defensive backs (DB; n = 8), linebackers (LB; n = 6), and running backs (RB; n = 4). Total and segmental body composition measured using MfBIA were compared with values obtained using DXA. Compared with DXA, MfBIA underestimated BF% (3.0 ± 3.8%), total FM (2.5 ± 4.3 kg), arm FM (0.4 ± 0.8 kg), arm FFM (1.4 ± 0.9 kg), leg FM (2.8 ± 2.0 kg), and leg FFM (5.4 ± 2.4 kg) (all p FFM (-2.4 ± 4.5 kg) (p FFM), ±3.83 kg (leg FM), ±4.62 kg (leg FFM), and ±8.83 kg (total FFM). No significant differences were observed between devices for trunk FM (-0.3 ± 3.0 kg; p = 0.565) and trunk FFM (0.4 ± 2.4 kg; p = 0.278), with LOAs of ±5.92 and ±4.69 kg, respectively. Player position significantly affected all between-device mean body composition measurement differences (adjusted p ≤ 0.05), with OL demonstrating the greatest effect on each variable. Therefore, MfBIA does not seem accurate in examining between-player body composition in college football players.

Bioimpedance spectroscopy for assessment of volume status in patients before and after general anaesthesia.

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Matthäus Ernstbrunner

Full Text Available BACKGROUND: Technically assisted assessment of volume status before surgery may be useful to direct intraoperative fluid administration. We therefore tested a recently developed whole-body bioimpedance spectroscopy device to determine pre- to postoperative fluid distribution. METHODS: Using a three-compartment physiologic tissue model, the body composition monitor (BCM, Fresenius Medical Care, Germany measures total body fluid volume, extracellular volume, intracellular volume and fluid overload as surplus or deficit of 'normal' extracellular volume. BCM-measurements were performed before and after standardized general anaesthesia for gynaecological procedures (laparotomies, laparoscopies and vaginal surgeries. BCM results were blinded to the attending anaesthesiologist and data analysed using the 2-sided, paired Student's t-test and multiple linear regression. RESULTS: In 71 females aged 45 ± 15 years with body weight 67 ± 13 kg and Duration of anesthesia 154 ± 69 minutes [corrected] duration of anaesthesia 154 ± 68 min, pre- to postoperative fluid overload increased from -0.7 ± 1.1 L to 0.1 ± 1.0 L, corresponding to -5.1 ± 7.5% and 0.8 ± 6.7% of normal extracellular volume, respectively (both p<0.001, after patients had received 1.9 ± 0.9 L intravenous crystalloid fluid. Perioperative urinary excretion was 0.3 ± 0.2 L [corrected]. The increase in extracellular volume was paralleled by an increase in total body fluid volume, while intracellular volume increased only slightly and without reaching statistical significance (p = 0.15. Net perioperative fluid balance (administered fluid volume minus urinary excretion was significantly associated with change in extracellular volume (r(2 = 0.65, but was not associated with change in intracellular volume (r(2 = 0.01. CONCLUSIONS: Routine intraoperative fluid administration results in a significant, and clinically meaningful increase in the extracellular compartment. BCM-measurements yielded

Lessons from Białowieża Forest on the history of protection and the world's first reintroduction of a large carnivore.

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Samojlik, Tomasz; Selva, Nuria; Daszkiewicz, Piotr; Fedotova, Anastasia; Wajrak, Adam; Kuijper, Dries Pieter Jan

2018-02-01

Understanding how the relationships between large carnivores and humans have evolved and have been managed through centuries can provide relevant insights for wildlife conservation. The management history of many large carnivores has followed a similar pattern, from game reserved for nobility, to persecuted pests, to conservation targets. We reconstructed the history of brown bear (Ursus arctos) management in Białowieża Forest (Poland and Belarus) based on a detailed survey of historical literature and Russian archives. From the end of the Middle Ages to the end of 18th century, the brown bear was considered "animalia superiora" (i.e., game exclusively reserved for nobility and protected by law). Bears, also a source of public entertainment, were not regarded as a threat. Effective measures to prevent damages to traditional forest beekeeping were already in practice. In the beginning of 19th century, new game-management approaches allowed most forest officials to hunt bears, which became the primary target of hunters due to their valuable pelt. This, together with an effective anticarnivore policy enhanced by bounties, led to bear extirpation in 1879. Different approaches to scientific game management appeared (planned extermination of predators and hunting levels that would maintain stable populations), as did the first initiatives to protect bears from cruel treatment in captivity. Bear reintroduction in Białowieża Forest began in 1937 and represented the world's first reintroduction of a large carnivore motivated by conservation goals. The outbreak of World War II spoiled what might have been a successful project; reproduction in the wild was documented for 8 years and bear presence for 13. Soft release of cubs born in captivity inside the forest but freely roaming with minimal human contact proved successful. Release of captive human-habituated bears, feeding of these bears, and a lack of involvement of local communities were weaknesses of the project

Assessing the Value of Biosimilars: A Review of the Role of Budget Impact Analysis.

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Simoens, Steven; Jacobs, Ira; Popovian, Robert; Isakov, Leah; Shane, Lesley G

2017-10-01

Biosimilar drugs are highly similar to an originator (reference) biologic, with no clinically meaningful differences in terms of safety or efficacy. As biosimilars offer the potential for lower acquisition costs versus the originator biologic, evaluating the economic implications of the introduction of biosimilars is of interest. Budget impact analysis (BIA) is a commonly used methodology. This review of published BIAs of biosimilar fusion proteins and/or monoclonal antibodies identified 12 unique publications (three full papers and nine congress posters). When evaluated alongside professional guidance on conducting BIA, the majority of BIAs identified were generally in line with international recommendations. However, a lack of peer-reviewed journal articles and considerable shortcomings in the publications were identified. Deficiencies included a limited range of cost parameters, a reliance on assumptions for parameters such as uptake and drug pricing, a lack of expert validation, and a limited range of sensitivity analyses that were based on arbitrary ranges. The rationale for the methods employed, limitations of the BIA approach, and instructions for local adaptation often were inadequately discussed. To understand fully the potential economic impact and value of biosimilars, the impact of biosimilar supply, manufacturer-provided supporting services, and price competition should be included in BIAs. Alternative approaches, such as cost minimization, which requires evidence demonstrating similarity to the originator biologic, and those that integrate a range of economic assessment methods, are needed to assess the value of biosimilars.

Randomized trial of bioelectrical impedance analysis versus clinical criteria for guiding ultrafiltration in hemodialysis patients: effects on blood pressure, hydration status, and arterial stiffness.

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Onofriescu, Mihai; Mardare, Nicoleta Genoveva; Segall, Liviu; Voroneanu, Luminiţa; Cuşai, Claudiu; Hogaş, Simona; Ardeleanu, Serban; Nistor, Ionuţ; Prisadă, Octavian Viorel; Sascău, Radu; Covic, Adrian

2012-04-01

Chronic fluid overload is common in maintenance hemodialysis (HD) patients and is associated with severe cardiovascular complications, such as arterial hypertension, left ventricular hypertrophy, congestive heart failure, and arrhythmia. Therefore, a crucial target of HD is to achieve the so-called dry weight; however, the best way to assess fluid status and dry weight is still unclear. Dry weight is currently determined in most dialysis units on a clinical basis, and it is commonly defined as the lowest body weight a patient can tolerate without developing intra-dialytic or inter-dialytic hypotension or other symptoms of dehydration. One of the most promising methods that have emerged in recent years is bioelectrical impedance analysis (BIA), which estimates body composition, including hydration status, by measuring the body's resistance and reactance to electrical current. Our objective was to study the effect BIA-guided versus clinical-guided ultrafiltration on various cardiovascular disease risk factors and markers in HD patients. We included 135 HD patients from a single center in a prospective study, aiming to compare the long-term (12 months) effect of BIA-based versus clinical-based assessment of dry weight on blood pressure (BP), pulse wave velocity (PWV), and serum N-terminal fragment of B-type natriuretic peptide (NT-proBNP). The body composition was measured using the portable whole-body multifrequency BIA device, Body Composition Monitor-BCM(®) (Fresenius Medical Care, Bad Homburg, Germany). In the "clinical" group there were no changes in BP, body mass index (BMI), and body fluids. The PWV increased from 7.9 ± 2.5 to 9.2 ± 3.6 m/s (P = 0.002), whereas serum NT-proBNP decreased from 5,238 to 3,883 pg/ml (P = 0.05). In the "BIA" group, BMI and body volumes also did not change; however, there was a significant decrease in both systolic BP, from 144.6 ± 14.7 to 135.3 ± 17.8 mmHg (P < 0.001), and diastolic BP, from 79.5 ± 9.7 to 73.2 ± 11.1 mmHg (P

Validity of bioelectrical impedance measurement in predicting fat-free mass of Chinese children and adolescents.

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Wang, Lin; Hui, Stanley Sai-chuen; Wong, Stephen Heung-sang

2014-11-15

The current study aimed to examine the validity of various published bioelectrical impedance analysis (BIA) equations in estimating FFM among Chinese children and adolescents and to develop BIA equations for the estimation of fat-free mass (FFM) appropriate for Chinese children and adolescents. A total of 255 healthy Chinese children and adolescents aged 9 to 19 years old (127 males and 128 females) from Tianjin, China, participated in the BIA measurement at 50 kHz between the hand and the foot. The criterion measure of FFM was also employed using dual-energy X-ray absorptiometry (DEXA). FFM estimated from 24 published BIA equations was cross-validated against the criterion measure from DEXA. Multiple linear regression was conducted to examine alternative BIA equation for the studied population. FFM estimated from the 24 published BIA equations yielded high correlations with the directly measured FFM from DEXA. However, none of the 24 equations was statistically equivalent with the DEXA-measured FFM. Using multiple linear regression and cross-validation against DEXA measurement, an alternative prediction equation was determined as follows: FFM (kg)=1.613+0.742×height (cm)2/impedance (Ω)+0.151×body weight (kg); R2=0.95; SEE=2.45 kg; CV=6.5, 93.7% of the residuals of all the participants fell within the 95% limits of agreement. BIA was highly correlated with FFM in Chinese children and adolescents. When the new developed BIA equations are applied, BIA can provide a practical and valid measurement of body composition in Chinese children and adolescents.

Higher insulin sensitivity in vegans is not associated with higher mitochondrial density.

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Gojda, J; Patková, J; Jaček, M; Potočková, J; Trnka, J; Kraml, P; Anděl, M

2013-12-01

Vegans have a lower incidence of insulin resistance (IR)-associated diseases and a higher insulin sensitivity (IS) compared with omnivores. The aim of this study was to examine whether the higher IS in vegans relates to markers of mitochondrial biogenesis and to intramyocellular lipid (IMCL) content. Eleven vegans and 10 matched (race, age, sex, body mass index, physical activity and energy intake) omnivorous controls were enrolled in a case-control study. Anthropometry, bioimpedance (BIA), ultrasound measurement of visceral and subcutaneous fat layer, parameters of glucose and lipid homeostasis, hyperinsulinemic euglycemic clamp and muscle biopsies were performed. Citrate synthase (CS) activity, mitochondrial DNA (mtDNA) and IMCL content were assessed in skeletal muscle samples. Both groups were comparable in anthropometric and BIA parameters, physical activity and protein-energy intake. Vegans had significantly higher glucose disposal (M-value, vegans 8.11±1.51 vs controls 6.31±1.57 mg/kg/min, 95% confidence interval: 0.402 to 3.212, P=0.014), slightly lower IMCL content (vegans 13.91 (7.8 to 44.0) vs controls 17.36 (12.4 to 78.5) mg/g of muscle, 95% confidence interval: -7.594 to 24.550, P=0.193) and slightly higher relative muscle mtDNA amount (vegans 1.36±0.31 vs controls 1.13±0.36, 95% confidence interval:-0.078 to 0.537, P=0.135). No significant differences were found in CS activity (vegans 18.43±5.05 vs controls 18.16±5.41 μmol/g/min, 95% confidence interval: -4.503 to 5.050, P=0.906). Vegans have a higher IS, but comparable mitochondrial density and IMCL content with omnivores. This suggests that a decrease in whole-body glucose disposal may precede muscle lipid accumulation and mitochondrial dysfunction in IR development.

Bioelectrical impedance vector analysis (BIVA for measuring the hydration status in young elite synchronized swimmers.

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Marta Carrasco-Marginet

Full Text Available The assessment of body hydration is a complex process, and no measurement is valid for all situations. Bioelectrical impedance vector analysis (BIVA has emerged as a relatively novel technique for assessing hydration status in sports. We applied BIVA a to determine hydration changes evoked by an intense synchronized swimming (SS training session; b to characterize the sample of young elite swimmers in relation with a nonathletic reference population; and c to generate its 50%, 75% and 95% percentiles of the bioelectrical variables.Forty-nine elite SS female swimmers of two age categories, comen (Co: 13.9 ± 0.9 years, n = 34 and junior (Jr: 16.3 ± 0.6 years, n = 15, performed a long, high intensity training session. Body mass (BM and bioelectrical variables (R, resistance; Xc, reactance; PA, phase angle; and Z, impedance module were assessed pre- and post-training. BIVA was used to characterize 1 the distribution pattern of the bioelectrical vector (BIA vector for both age groups, and 2 pre- to post-training BIA vector migration. Bioelectrical variables were also correlated with BM change values.Most swimmers were mostly located outside the 75% and some beyond the 95% percentile of the bioelectrical tolerance ellipses of the general population. The BIA vector showed statistically significant differences in both Co (T2 = 134.7, p = 0.0001 and Jr (T2 = 126.2, p < 0.001. Both groups were also bioelectrically different (T2 = 17.6, p < 0.001. After the training session, a decrease in BM (p = 0.0001 and an increase in BIA variables (p = 0.01 was observed. BIVA also showed a significant pre-post vector migration both in Co (T2 = 82.1; p < 0.001 and Jr (T2 = 41.8; p < 0.001. No correlations were observed between BM changes and bioelectrical variables.BIVA showed specific bioelectrical characteristics in young elite SS athletes. Considering the decrease in BM and the migration of the BIA vector, we conclude that the homeostatic hydration status of these

Bioelectrical impedance for detecting and monitoring lymphedema in patients with breast cancer. Preliminary results of the florence nightingale breast study group.

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Erdogan Iyigun, Zeynep; Selamoglu, Derya; Alco, Gul; Pilancı, Kezban Nur; Ordu, Cetin; Agacayak, Filiz; Elbüken, Filiz; Bozdogan, Atilla; Ilgun, Serkan; Guler Uysal, Fusun; Ozmen, Vahit

2015-03-01

The aim of this study was to evaluate the efficacy of bioimpedance spectroscopy for the follow-up of patients with lymphedema in Turkey and its benefits in the diagnosis of stage 0, 1, and 2 lymphedema in patients who are under treatment for breast cancer. Thirty-seven female patients with breast cancer who underwent surgical procedures in our Breast Health Centre were followed up for lymphedema using bioimpedance, and clinical measurements were taken for a minimum period of 1 year at 3-month intervals. Patients who had been monitored regularly between November, 2011, and September, 2013, were enrolled to the study. In total, 8 patients developed lymphedema with an overall rate of 21.6%. Among the 8 patients who developed lymphedema, 4 had Stage 2, 1 had Stage 1, and 3 had Stage 0 lymphedema. Stage 0 lymphedema could not be detected with clinical measurements. During the patients' 1-year follow-up period using measurements of bioimpedance, a statistically significant relationship was observed between the occurrence of lymphedema and the disease characteristics. including the number of the extracted and remaining lymph nodes and the region of radiotherapy (p=0.042, p=0.024, p=0.040). Bioimpedance analysis seems to be a practical and reliable method for the early diagnosis of lymphedema. It is believed that regular monitoring of patients in the high-risk group using bioimpedance analyses increases the ability to treat lymphedema.

USO DE REMEDIADORES BIOLÓGICOS NA BIODIGESTÃO ANAERÓBIA DA CAMA DE FRANGO DE CORTE / USE OF BIOLOGICAL REMEDIATION IN ANAEROBIC BIO-DIGESTION OF THE POULTRY LITTER

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L. V. C. DA COSTA

2012-11-01

Full Text Available A cama de frango subproduto gerado na produção de aves de corte, vem sendo cada vez mais reutilizada pelos produtores, sendo essa cama muitas vezes composta por produtos disponível em determinada região, como o bagaço de cana,casca de amendoim, casca de arroz, etc, produtos esses classificados como altamente lignificados e de difícil degradação,principalmente quando se trabalha com tratamento em biodigestão anaeróbia, dificultando a atuação de bactérias metanogênicas.Baseado nesse exposto, o objetivo desse  trabalho foi avaliar a inclusão de remediadores biológicos na biodigestão anaeróbia da cama de frango que tiveram ou não a separação da fase sólida e líquida  e seu efeito na produção e qualidade de biogás. Foram utilizados 12 biodigestores modelo batelada de bancada abastecidos com cama de frango de 3º lote de reutilização e remediadores biológicos comercial. O tempo de retenção hidráulica foi de 120 dias. Observou-se que os tratamentos que não tiveram a separação de sólidos adicionados de remediadores biológicos foram os que mais produziram biogás, e a porcentagem de metano pelas médias não apresentou diferença entre os tratamentos. 

Habitat Preferences of Boros schneideri (Coleoptera: Boridae) in the Natural Tree Stands of the Białowieża Forest

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Gutowski, Jerzy M.; Sućko, Krzysztof; Zub, Karol; Bohdan, Adam

2014-01-01

Abstract We analyzed habitat requirements of Boros schneideri (Panzer, 1796) (Coleoptera: Boridae) in the natural forests of the continental biogeographical region, using data collected in the Białowieża Forest. This species has been found on the six host trees, but it preferred dead, standing pine trees, characterized by large diameter, moderately moist and moist phloem but avoided trees in sunny locations. It occurred mostly in mesic and wet coniferous forests. This species demonstrated preferences for old tree stands (over 140-yr old), and its occurrence in younger tree-stand age classes (minimum 31–40-yr old) was not significantly different from random distribution. B. schneideri occupied more frequently locations distant from the forest edge, which were less affected by logging. Considering habitat requirements, character of occurrence, and decreasing number of occupied locations in the whole range of distribution, this species can be treated as relict of primeval forests. PMID:25527586

Is bioelectrical impedance accurate for use in large epidemiological studies?

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Merchant Anwar T

2008-09-01

Full Text Available Abstract Percentage of body fat is strongly associated with the risk of several chronic diseases but its accurate measurement is difficult. Bioelectrical impedance analysis (BIA is a relatively simple, quick and non-invasive technique, to measure body composition. It measures body fat accurately in controlled clinical conditions but its performance in the field is inconsistent. In large epidemiologic studies simpler surrogate techniques such as body mass index (BMI, waist circumference, and waist-hip ratio are frequently used instead of BIA to measure body fatness. We reviewed the rationale, theory, and technique of recently developed systems such as foot (or hand-to-foot BIA measurement, and the elements that could influence its results in large epidemiologic studies. BIA results are influenced by factors such as the environment, ethnicity, phase of menstrual cycle, and underlying medical conditions. We concluded that BIA measurements validated for specific ethnic groups, populations and conditions can accurately measure body fat in those populations, but not others and suggest that for large epdiemiological studies with diverse populations BIA may not be the appropriate choice for body composition measurement unless specific calibration equations are developed for different groups participating in the study.

Comparison of body composition methods during weight loss in obese women using herbal formula.

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Kim, Ho-Jun; Gallagher, Dympna; Song, Mi-Yeon

2005-01-01

Bioelectrical impedance analysis (BIA), a device that analyzes the current conduction differences between the fat and water components is widely used for reasons that include convenience of use, non-invasiveness, safety, and low cost. Dual energy X-ray absorptiometry (DXA) allows for the assessment of total body and regional lean and fat tissues and bone mineral content (BMC). The objective of this study was to compare body composition assessments by BIA and DXA before and after a 6-week herbal diet intervention program in 50 pre-menopausal women [mean +/- SD: age 30.58 +/- 6.15, body mass index (BMI) 31.72 +/- 3.78]. Waist-to-hip ratio (WHR) was measured by BIA and anthropometry. Lean body mass (LBM), body fat (BF), BMC and percent body fat (%BF) were measured by BIA and DXA. Highly significant correlations were observed between BIA and DXA measurements for LBM, BF, BMC and %BF (r = 0.73, 0.93, 0.53, 0.79, respectively) before the intervention. Differences between BIA and DXA measurements were observed in LBM, BF, %BF and BMC before intervention (p produce statistically comparable results in pre-menopausal Korean women and therefore should not be used interchangeably when measuring body composition.

Modernization Of Public Space Floor And Its Impact On Area - The Example Of The Kościuszko Square In Białystok

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Tofiluk Anna

2015-12-01

Full Text Available The last 25 years have been in many Polish cities a period of intensive modernization and renewals of the existing public spaces. Most of all the resurfacing of the pavement and changing of street furniture have been held. In many cases, the transformations in the urban areas were integrated with exclusion from traffic. The question arises what criteria architects or landscape architects follow and what design solutions apply. It is also interesting how the new shape of the floor in public spaces (understood here as a pavement and street furniture together can help to create integrating and activating space for residents. And how it can affect the quality of life in a wider area. This article attempts to answer these questions based on new solutions on Kosciuszko Square in Białystok, executed in 2005-2009.

Cervical cancer detection by electrical impedance in a Colombian setting

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A Miranda, David; P Corzo, Sandra; Correa, C A González

2013-01-01

Electrical properties of normal and neoplastic cervical tissues in a heterogeneous group of 56 Colombian women were studied by electrical impedance spectroscopy and a model based on the Generalized Effective-Medium Theory of Induced Polarization (GEMTIP). Differences between the electrical bioimpedance spectra were correlated with cellular and tissue parameters. The analysis performed by the proposed model suggest that the number of different types of cellular layers that form the biological tissue, the intracellular and extracellular conductivity could be used to explain the differences between electrical bioimpedance spectra in normal and neoplastic tissues.

Comparison of bioimpedance and dual-energy x-ray absorptiometry for measurement of fat mass in hemodialysis patients.

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Molfino, Alessio; Don, Burl R; Kaysen, George A

2012-01-01

Fat mass (FM) is measured with dual-energy X-ray absorptiometry (DXA), but is expensive and not portable. Multifrequency bioimpedance spectroscopy (BIS) measures total body water (TBW), intracellular water (ICW) and extracellular water (ECW). FM is calculated by subtracting fat-free mass (FFM) from weight assuming a fractional hydration of FFM of 0.73. Hemodialysis (HD) patients, however, have nonphysiologic expansion of ECW. Our aim was to apply a model to estimate FM in HD patients and controls. We estimated the hydration of FFM in healthy subjects and HD patients with BIS (Impedimed multifrequency) assuming a hydration of 0.73 or using a model allowing ECW and ICW to vary, deriving a value for FM accounting for variances in ECW and ICW. FM was measured by DXA (Hologic Discovery W) in 25 controls and in 11 HD patients. We measured TBW, ECW and ICW with BIS and calculated FM using either weight - TBW/0.73 or with a model accounting for variations in ECW/ICW to estimate FM. ECW/ICW was greater in HD patients than in controls (0.83 ± 0.08 vs. 0.76 ± 0.04; p = 0.001). FM (kg) measured by DXA or estimated from TBW using constant hydration or accounting for variations in ECW/ICW was not significantly different in controls or in HD patients. Values obtained by all methods correlated (p measured by DXA and by BIS in both controls and HD patients combined correlated (r(2) = 0.871). Expansion of ECW in HD patients is statistically significant; however, the effect on hydration of FFM was insufficient to cause significant deviation from values derived using a hydration value of 0.73 within the range of expansion of ECW in the HD patient population studied here. Copyright © 2013 S. Karger AG, Basel.

Modelling a budgetary impact analysis for funding drug-based smoking cessation therapies for patients with major depressive disorder in Spain.

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Rejas-Gutiérrez, J; Bruguera, E; Cedillo, S

2017-09-01

Smoking is associated with high healthcare resource utilisation and cost to society. Patients with major depressive disorder (MDD) exhibit high susceptibility to nicotine dependence. Varenicline, bupropion and nicotine replacement therapy are all indicated for smoking cessation; however funding by the Spanish national health system (SNHS) is limited. We modelled a budgetary impact analysis (BIA) to estimate the impact of the SNHS funding drug-based therapies for smoking cessation in smokers with MDD. The BIA compared the current unfunded scenario versus a funded scenario (varenicline, bupropion, nicotine replacement therapy combined with medical follow-up and counselling) using the Spanish SNHS and societal perspectives. The BIA design was a hybrid model using a decision tree algorithm (population size: smokers with MDD) and Markov chains (smoking cessation attempts) over a 5-year horizon. Smoking cessation drug efficacy was derived from clinical trials, and smoking cessation costs avoided were taken from an analysis of the Spanish National Health Survey. Results were shown as incremental cost savings. Scenarios and threshold univariate sensitivity analyses tested model robustness. The funded scenario resulted in an increase of 43,478 cessation attempts and 8930 fewer smokers after 5 years compared to the unfunded scenario. The cost of funding was €25.3 million and costs avoided were €26.5 million. There was a cumulative 5-year incremental cost saving of €1.2 million to Spanish society. Results were robust using alternative scenarios. Funding smoking cessation drugs in patients with MDD is of economic benefit to Spain and could produce net savings from the third year of implementation. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

A Novel Non-Iterative Method for Real-Time Parameter Estimation of the Fricke-Morse Model

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SIMIC, M.

2016-11-01

Full Text Available Parameter estimation of Fricke-Morse model of biological tissue is widely used in bioimpedance data processing and analysis. Complex nonlinear least squares (CNLS data fitting is often used for parameter estimation of the model, but limitations such as high processing time, converging into local minimums, need for good initial guess of model parameters and non-convergence have been reported. Thus, there is strong motivation to develop methods which can solve these flaws. In this paper a novel real-time method for parameter estimation of Fricke-Morse model of biological cells is presented. The proposed method uses the value of characteristic frequency estimated from the measured imaginary part of bioimpedance, whereupon the Fricke-Morse model parameters are calculated using the provided analytical expressions. The proposed method is compared with CNLS in frequency ranges of 1 kHz to 10 MHz (beta-dispersion and 10 kHz to 100 kHz, which is more suitable for low-cost microcontroller-based bioimpedance measurement systems. The obtained results are promising, and in both frequency ranges, CNLS and the proposed method have accuracies suitable for most electrical bioimpedance (EBI applications. However, the proposed algorithm has significantly lower computation complexity, so it was 20-80 times faster than CNLS.

[Fixed drug combinations in hypertension: a budget impact analysis for the Spanish Health System on the marketing of a fixed combination of olmesartan/amlodipine].

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Belén Ferro-Rey, M; Roca-Cusachs, Alex; Sicras-Mainar, Antoni; Alvarez-Martín, Carlos; de Salas-Cansado, Marina

2011-07-01

To carry out a budget impact analysis (BIA) of olmesartan/amlodipine (20/5, 40/5 and 40/10mg) marketed as a fixed combination (FC) in its approved indication for the National Health System (NHS). We developed a decision tree model in order to estimate usual hypertension treatment algorithm in Spanish clinical practice. The BIA has been developed from the perspective of the NHS for a period of 3 years (years 2010-2012). Spanish hypertensive population ≥ 35 years old. Introduction into the market of a fixed combination (FC) olmesartan/amlodipine in Spain. Expected costs to be assumed by the Spanish NHS (RRP-VAT) for hypertensive population able to be treated with the FC versus currently assumed costs by the NHS with free combination olmesartan and amlodipine. Estimated pharmaceutical costs in hypertensive population treated with olmesartan and amlodipine (2 pills) would be €25.2M (1(st) year), €26.4M (2011), €27.6M (2012), with a total 3-year period of €79.2M. According to patient tree model, the population able to be treated with FC would be 71,283 patients (2010), with a growth rate of 4.8% in the successive years, which supposes an annual cost of €21.2M (2010), €21.8M (2011) and €22.4M (2012), with a total 3-year period of €65.4M. The BIA shows savings of €13.8M in a total 3-year period. The BIA of FC olmesartan/amlodipine could generate net savings of €13.8M for the NHS in the period ranging from years 2010 to 2012. Copyright © 2010 Elsevier España, S.L. All rights reserved.

Hydration abnormalities in Nigerian patients on chronic hemodialysis.

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Tzamaloukas, Antonios H; Onime, Aideloje; Agaba, Emmanuel I; Vanderjagt, Dorothy J; Ma, Irene; Lopez, Andrea; Tzamaloukas, Rolinda A; Glew, Robert H

2007-10-01

The state of hydration affects the outcomes of chronic dialysis. Bioelectrical impedance analysis (BIA) provides estimates of body water (V), extracellular volume (ECFV), and fat-free mass (FFM) that allow characterization of hydration. We compared single-frequency BIA measurements before and after 14 hemodialysis sessions in 10 Nigerian patients (6 men, 4 women; 44+/-7 years old) with clinical evaluation (weight removed during dialysis, presence of edema) and with estimates of body water obtained by the Watson, Chertow, and Chumlea anthropometric formulas. Predialysis and postdialysis values of body water did not differ between BIA and anthropometric estimates. However, only the BIA estimate of the change in body water during dialysis (-0.8+/-2.9 L) did not differ from the corresponding change in body weight (-1.3+/-3.0 kg), while anthropometric estimates of the change in body water were significantly lower, approximately one-third of the change in weight. Bioelectrical impedance analysis correctly detected the intradialytic change in body water content (the ratio V/Weight) in 79% of the cases, while anthropometric formula estimates of the same change were erroneous in each case. Compared with patients with clinical postdialysis euvolemia (n=7), those with postdialysis edema (n=5) had higher values of postdialysis BIA ratios V/FFM (0.77+/-0.01 vs. 0.72+/-0.03, phydration in patients on chronic hemodialysis. In contrast, BIA provides estimates of hydration agreeing with clinical estimates in the same patients, although it tends to underestimate body water and extracellular volume in patients with large collections of fluid in central body cavities.

What is the budget impact of a new treatment or new health technology arriving on the market?

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Dervaux, Benoit; Le Fur, Camille; Dubois, Sophie; Josseran, Anne

2017-02-01

In France, market access for innovative drugs (level I, II & III improvement of medical service rendered having significant impact on health insurance expenditure) involves medico-economic evaluation. In addition to cost-effectiveness analysis (CEA), budget impact analysis (BIA) can be performed, especially since the sustainability of the health insurance system has become a growing concern for all stakeholders. The members of the Giens 2016 round table discussed the contribution of BIA based on a review of the literature on distribution models, the participants' experiences including experience related to the modalities of hospital assessments, and examples from other countries. The round table established recommendations on four elements of interest: 1: the use of BIA from a contractual point of view - between manufacturers and the French Economic Committee for Health Products - during the price negotiations process, and from a prospective point of view within the framework of the annual review of budget expenditures; the definition of the target population and the rhythm of a health product's distribution are also major elements; 2: the interpretation of BIA results in light of CEA results: for what products and at what moment in the life cycle of these products; 3: the integration of the rhythm of a health product's distribution into the BIA; 4: preoccupations about how the level of health product implementation is integrated into the BIA in terms of opportunity cost and organisational quality for the promoter. Copyright © 2017 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

Cross-mode bioelectrical impedance analysis in a standing position for estimating fat-free mass validated against dual-energy x-ray absorptiometry.

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Huang, Ai-Chun; Chen, Yu-Yawn; Chuang, Chih-Lin; Chiang, Li-Ming; Lu, Hsueh-Kuan; Lin, Hung-Chi; Chen, Kuen-Tsann; Hsiao, An-Chi; Hsieh, Kuen-Chang

2015-11-01

Bioelectrical impedance analysis (BIA) is commonly used to assess body composition. Cross-mode (left hand to right foot, Z(CR)) BIA presumably uses the longest current path in the human body, which may generate better results when estimating fat-free mass (FFM). We compared the cross-mode with the hand-to-foot mode (right hand to right foot, Z(HF)) using dual-energy x-ray absorptiometry (DXA) as the reference. We hypothesized that when comparing anthropometric parameters using stepwise regression analysis, the impedance value from the cross-mode analysis would have better prediction accuracy than that from the hand-to-foot mode analysis. We studied 264 men and 232 women (mean ages, 32.19 ± 14.95 and 34.51 ± 14.96 years, respectively; mean body mass indexes, 24.54 ± 3.74 and 23.44 ± 4.61 kg/m2, respectively). The DXA-measured FFMs in men and women were 58.85 ± 8.15 and 40.48 ± 5.64 kg, respectively. Multiple stepwise linear regression analyses were performed to construct sex-specific FFM equations. The correlations of FFM measured by DXA vs. FFM from hand-to-foot mode and estimated FFM by cross-mode were 0.85 and 0.86 in women, with standard errors of estimate of 2.96 and 2.92 kg, respectively. In men, they were 0.91 and 0.91, with standard errors of the estimates of 3.34 and 3.48 kg, respectively. Bland-Altman plots showed limits of agreement of -6.78 to 6.78 kg for FFM from hand-to-foot mode and -7.06 to 7.06 kg for estimated FFM by cross-mode for men, and -5.91 to 5.91 and -5.84 to 5.84 kg, respectively, for women. Paired t tests showed no significant differences between the 2 modes (P > .05). Hence, cross-mode BIA appears to represent a reasonable and practical application for assessing FFM in Chinese populations. Copyright © 2015 Elsevier Inc. All rights reserved.

What´s cheapest, intravenous iron sucrose- or intravenous iron carboxymaltose treatment in IBD patients?

DEFF Research Database (Denmark)

Bager, Palle; Dahlerup, Jens Frederik

a Budget Impact Analysis (BIA) from a hospital perspective, a Cost Effective Analysis (CEA) from a patient perspective and a Cost Benefit Analysis (CBA) consecutively including 20 IBD patients' willingness-to-pay' (WTP) assessment. BIA and CEA analysis were based on total infusion-doses from 500 mg Fe......-effective than iron sucrose, due to fewer outpatient setting visits. As IBD-patients could have less income as the average of the background population due to disease activity, sensitivity analysis using a 50% income level were done, showing the same tendency but less significant. The average patients WTP...

Performance evaluation of wideband bio-impedance spectroscopy using constant voltage source and constant current source

International Nuclear Information System (INIS)

Mohamadou, Youssoufa; Oh, Tong In; Wi, Hun; Sohal, Harsh; Farooq, Adnan; Woo, Eung Je; McEwan, Alistair Lee

2012-01-01

Current sources are widely used in bio-impedance spectroscopy (BIS) measurement systems to maximize current injection for increased signal to noise while keeping within medical safety specifications. High-performance current sources based on the Howland current pump with optimized impedance converters are able to minimize stray capacitance of the cables and setup. This approach is limited at high frequencies primarily due to the deteriorated output impedance of the constant current source when situated in a real measurement system. For this reason, voltage sources have been suggested, but they require a current sensing resistor, and the SNR reduces at low impedance loads due to the lower current required to maintain constant voltage. In this paper, we compare the performance of a current source-based BIS and a voltage source-based BIS, which use common components. The current source BIS is based on a Howland current pump and generalized impedance converters to maintain a high output impedance of more than 1 MΩ at 2 MHz. The voltage source BIS is based on voltage division between an internal current sensing resistor (R s ) and an external sample. To maintain high SNR, R s is varied so that the source voltage is divided more or less equally. In order to calibrate the systems, we measured the transfer function of the BIS systems with several known resistor and capacitor loads. From this we may estimate the resistance and capacitance of biological tissues using the least-squares method to minimize error between the measured transimpedance excluding the system transfer function and that from an impedance model. When tested on realistic loads including discrete resistors and capacitors, and saline and agar phantoms, the voltage source-based BIS system had a wider bandwidth of 10 Hz to 2.2 MHz with less than 1% deviation from the expected spectra compared to more than 10% with the current source. The voltage source also showed an SNR of at least 60 dB up to 2.2 MHz

Body composition as an indicator of the nutritional status in children with newly diagnosed ulcerative colitis and Crohn’s disease – a prospective study

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Paweł Więch

2016-12-01

Full Text Available Introduction : The prevalence of nutritional status disorders in children with ulcerative colitis (UC is much lower than in the case of Crohn’s disease (CD. The largest variability in the components of body composition occurs at the time of a new diagnosis and in periods of disease exacerbation. Aim: Assessment of body composition in children with UC and CD. Material and methods: The preliminary study included 59 children with inflammatory bowel disease (IBD (34 children with UC vs. 25 children with CD aged 4–18 years. The final analysis included 26 newly diagnosed children (16 children with UC vs. 10 children with CD. The evaluation of body composition was conducted by means of BIA-101 bioimpedance analyser. Results : Decreased values of lean mass were found in children with newly diagnosed IBD (UC: 41.13 kg vs. control group: 42.06 kg; CD: 35.50 kg vs. control group: 45.50 kg. After a year interval, an increase in fat (UC 1: 7.67 kg vs. UC 2: 10.33 kg; CD 1: 7.36 kg vs. CD 2: 9.47 kg as well as lean body mass (UC 1: 35.22 kg vs. UC 2: 39.00 kg; CD 1: 35.99 kg vs. CD 2: 42.41 kg was found in children. Conclusions : Children with newly diagnosed IBD were highly vulnerable to nutritional status disturbances. The increase in fat and lean body mass in an annual interval may be due to the treatment regime and control of the children.

Comparison of multiple fluid status assessment methods in patients on chronic hemodialysis.

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Alexiadis, Giannis; Panagoutsos, Stelios; Roumeliotis, Stefanos; Stibiris, Ilias; Markos, Angelos; Kantartzi, Konstantia; Passadakis, Ploumis

2017-03-01

Control of hydration status is an important constituent of adequate and efficient hemodialysis (HD) treatment. Nevertheless, there are no precise clinical indices for early recognition of small changes in fluid status of patients undergoing chronic hemodialysis therapy. This study aimed to evaluate and compare the widely used and reliable method of indexed inferior vena cava diameter (IVCDi) with established and more recently available techniques (bioelectrical impedance analysis [BIA], continuous blood volume monitoring [Crit-line], and the B-line score [BLS] with lung ultrasonography) for estimating the hydration status of patients on HD. Fifty-three patients undergoing chronic HD thrice weekly were included in the study. Evaluation of hydration status methods (IVCDi, BLS, BIA, and Crit-line) was performed thrice weekly before and after HD. Receiver operating characteristic curve analysis was performed to evaluate the discriminative power of (methods) the BLS, BIA, and Crit-line for predicting over- and underhydration of patients, as determined by the reference method, IVCDi. BLS showed the most promising results in predicting overhydration, as determined by IVCDi, compared with BIA and Crit-line and presented a sensitivity of 77% and specificity of 74%. The accuracy of the BLS was higher than that of BIA (0.81 vs. 0.71, p = 0.032) and Crit-line (0.61, p = 0.001). BLS also showed more promising results in predicting underhydration, as determined by IVCDi, than BIA and Crit-line and presented a sensitivity of 78% and a specificity of 73%. The accuracy of the BLS was higher than that of BIA (0.83 vs. 0.76, p = 0.035) and Crit-line (0.50, p < 0.001). The BLS is a useful and easily performed technique that has recently become available for accurate evaluation of dry weight and fluid status in patients with end-stage renal disease undergoing chronic HD. This method might help recognize asymptomatic lung congestion in these patients.

A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care.

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Mourtzakis, Marina; Prado, Carla M M; Lieffers, Jessica R; Reiman, Tony; McCargar, Linda J; Baracos, Vickie E

2008-10-01

Human body composition is important in numerous cancer research domains. Our objective was to evaluate clinically accessible methods to achieve practical and precise measures of body composition in cancer patients. Dual-energy X-ray absorptiometry (DXA)-based analysis of fat and fat-free mass was performed in 50 cancer patients and compared with bioelectrical impedance analysis (BIA) and with regional computed tomography (CT) images available in the patients' medical records. BIA overestimated or underestimated fat-free mass substantially compared with DXA as the method of reference (up to 9.3 kg difference). Significant changes in fat-free mass over time detected with DXA in a subset of 21 patients (+2.2 +/- 3.2%/100 days, p = 0.003), was beyond the limits of detection of BIA. Regional analysis of fat and fat-free tissue at the 3rd lumbar vertebra with either DXA or CT strongly predicted whole-body fat and fat-free mass (r = 0.86-0.94; p body composition.

Comparação da potência anaeróbia entre as posições táticas em jogadores de futebol: estudo retrospectivo

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Tiago Cetolin

2013-05-01

Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2013v15n4p507 O objetivo do estudo foi comparar a Potência anaeróbia máxima (Pmáx; Potência anaeróbia média (Pmed e índice de fadiga (IF entre atletas de diferentes posições táticas no futebol. Para isso, 248 atletas profissionais de futebol de campo (25,8±1,72 anos, 77,52±4,90 Kg e 178,48±5,63 cm, pertencentes a 1ª e 2ª divisão do estado do Rio Grande do Sul, avaliados durante o período de 1999-2010, divididos em cinco posições táticas: goleiros (GO (n=28, laterais (LA (n=35, zagueiros (ZA (n=54, meio-campistas (MC (n=81 e atacantes (AT (n=50. Os atletas executaram o RAST test para determinar a Pmáx, Pmed e IF. Foi utilizada a ANOVA One Way e post hoc de Tukey adotando-se o valor de significância de p<0,05. Diferenças significativas para a Pmáx (p<0,05 dos LA comparadas aos GO, ZAe MC; da Pmed dos LA para os GO, ZA e MC e dos AT e MC em relação aos GO(p<0,05. Na potência relativa de cada sprint, houve manutenção durante o 1º e 2º sprint entre as posições, exceto os MC e durante o 5º e 6º sprint, independente da posição, não houve decréscimo do desempenho de potência. Visto que foram encontradas diferenças significativas de Pmáx e da Pmed, dos LA em relação aos GO, ZA e MC, concluímos que esta evidência confirma que atletas de diferentes posições táticas apresentam variação quanto às características de suas ações.

Changes in body composition during weight loss in obese subjects in the NUGENOB study

DEFF Research Database (Denmark)

Verdich, C.; Barbe, P.; Petersen, Martin

2011-01-01

AIM: We studied the accuracy of bioelectrical impedance analysis (BIA) to assess changes in body composition during moderate weight loss in obese subjects. METHODS: Estimates of changes in fat mass (FM) and fat-free mass (FFM) by BIA were compared with those by dual-energy X-ray absorptiometry (DXA...... DPX-IQ at two centres, Hologic QDR 2000 at another centre) at baseline (n=131) and at week 10 (n=105) after a mean weight loss of -5.7kg. RESULTS: At baseline, BIA significantly overestimated FFM and underestimated FM (by 1-3kg on average) compared with DXA, and the limits of agreement were wide (mean......±7-8.5kg). For body-composition changes, although biases were generally non-significant, the limits of agreement were also wide (mean±3.7-4.6kg). An FFM prediction equation for BIA data was developed in subjects scanned with Lunar instruments and cross-validated in an independent sample of 31 obese...

Next-generation sequencing in NSCLC and melanoma patients: a cost and budget impact analysis

Science.gov (United States)

van Amerongen, Rosa A; Retèl, Valesca P; Coupé, Veerle MH; Nederlof, Petra M; Vogel, Maartje J; van Harten, Wim H

2016-01-01

Next-generation sequencing (NGS) has reached the molecular diagnostic laboratories. Although the NGS technology aims to improve the effectiveness of therapies by selecting the most promising therapy, concerns are that NGS testing is expensive and that the ‘benefits’ are not yet in relation to these costs. In this study, we give an estimation of the costs and an institutional and national budget impact of various types of NGS tests in non-small-cell lung cancer (NSCLC) and melanoma patients within The Netherlands. First, an activity-based costing (ABC) analysis has been conducted on the costs of two examples of NGS panels (small- and medium-targeted gene panel (TGP)) based on data of The Netherlands Cancer Institute (NKI). Second, we performed a budget impact analysis (BIA) to estimate the current (2015) and future (2020) budget impact of NGS on molecular diagnostics for NSCLC and melanoma patients in The Netherlands. Literature, expert opinions, and a data set of patients within the NKI (n = 172) have been included in the BIA. Based on our analysis, we expect that the NGS test cost concerns will be limited. In the current situation, NGS can indeed result in higher diagnostic test costs, which is mainly related to required additional tests besides the small TGP. However, in the future, we expect that the use of whole-genome sequencing (WGS) will increase, for which it is expected that additional tests can be (partly) avoided. Although the current clinical benefits are expected to be limited, the research potentials of NGS are already an important advantage. PMID:27899957

[Professional dysphonia and its risk factors in the material of the outpatient clinic of the Department of Otolaryngology, Medical Academy of Białystok].

Science.gov (United States)

Kosztyła-Hojna, Bozena; Rogowski, Marek; Ruczaj, Jan; Pepiński, Witold

2004-01-01

Occurrence of professional dysphonia was analysed in a group of 309 patients treated in the Phoniatric Outpatient Clinic, Department of Otolaryngology, Medical Academy in Białystok through the period of 1999-2001. In a group of professional voice users female teachers of primary schools and lower secondary schools predominated. Obtained results were compared with those from a group of 65 persons of other occupations. In the both groups other harmful factors affecting the voice organ were excluded. The clinical assessment included subjective and objective laryngological examination using videolaryngostroboscopy. The clinical material was evaluated in a view of functional and organic disorders of the voice organ. Early occurrence and aggravation of functional changes in the larynx was recorded in non professional voice users in the course of their seniority. In professional patients organic changes were more common and occurred earlier than functional disorders. Severity of dysphonia was related to the larynx pathology, especially of a functional character.

A Comprehensive Diagnostic Framework for Evaluating Business Intelligence and Analytics Effectiveness

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Neil Foshay

2015-09-01

Full Text Available Business intelligence and analytics (BIA initiatives are costly, complex and experience high failure rates. Organizations require effective approaches to evaluate their BIA capabilities in order to develop strategies for their evolution. In this paper, we employ a design science paradigm to develop a comprehensive BIA effectiveness diagnostic (BIAED framework that can be easily operationalized. We propose that a useful BIAED framework must assess the correct factors, should be deployed in the proper process context and acquire the appropriate input from different constituencies within an organization. Drawing on the BIAED framework, we further develop an online diagnostic toolkit that includes a comprehensive survey instrument. We subsequently deploy the diagnostic mechanism within three large organizations in North America (involving over 1500 participants and use the results to inform BIA strategy formulation. Feedback from participating organizations indicates that BIA diagnostic toolkit provides insights that are essential inputs to strategy development. This work addresses a significant research gap in the area of BIA effectiveness assessment.

Desempenho da potência anaeróbia em atletas de elite do mountain bike submetidos à suplementação aguda com creatina Anaerobic power output of elite off-road cyclists with acute oral creatine supplementation

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Guilherme Eckhardt Molina

2009-10-01

Full Text Available Com o objetivo de investigar os efeitos da suplementação aguda com creatina no desempenho da potência anaeróbia de atletas de elite do mountain bike, 20 atletas em período básico do macrociclo de treinamento foram distribuídos aleatoriamente (duplo-cego em dois grupos: placebo (PLA, n = 10 e creatina (CRE, n = 10. Foram avaliados quanto à composição corporal (pesagem hidrostática e potência anaeróbia (teste de Wingate - TW antes (PRÉ e depois (PÓS de sete dias de suplementação. A creatina ou maltodextrina foi usada em três doses diárias de 0,3g/kg de massa corporal diluídos em meio líquido adoçado. Não foram observadas diferenças significativas nas variáveis morfológicas após sete dias de suplementação (PRÉ x PÓS, e os grupos não diferiram apesar da variação percentual (Δ% contrária (positiva para o grupo CRE e negativa para o PLA. A potência anaeróbia pico (PP e o instante da potência pico (IPP aumentaram e o índice de fadiga diminuiu do PRÉ para o PÓS-testes no grupo CRE, enquanto que o grupo PLA não apresentou diferenças significantes. A PP apresentou forte tendência em ser maior e o IPP foi maior no grupo CRE comparado com o PLA. Conclui-se que existem evidências de que a suplementação com creatina (0,3g/kg em curto prazo (sete dias pode retardar o IPP (CRE 3,0 ± 0,5/3,6 ± 0,8 Δ%= 20% no teste de Wingate em atletas de elite do mountain bike, sugerindo que a suplementação com creatina pode melhorar o desempenho físico quanto à potência anaeróbia durante o trabalho de alta intensidade e curta duração.In order to investigate the effect of a high dose, acute oral creatine supplementation on anaerobic power of male off-road cyclists, twenty elite athletes training at the basic period were randomly (double-blind assigned into 2 groups: placebo (PLA n=10 and creatine (CRE n=10. They were submitted to a body composition evaluation (underwater weighting and Wingate Anaerobic Test (TW before

Breath Analysis and the Measurement of Total Body Water Using Isotope Dilution - Applications in the Dialysis Clinic

Czech Academy of Sciences Publication Activity Database

Davies, S. J.; Engel, B.; Chan, C.; Tan, B. K.; Yu, Z.; Asghar, R. B.; John, B.; Španěl, Patrik; Smith, D.

2013-01-01

Roč. 9, č. 4 (2013), s. 593-599 ISSN 1573-4110 R&D Projects: GA ČR GA203/00/0632 Institutional support: RVO:61388955 Keywords : bioimpedance * body composition * dialysis Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 1.194, year: 2013

Assessment of fat-free mass from bioelectrical impedance analysis in obese women with Prader-Willi syndrome.

Science.gov (United States)

Bedogni, Giorgio; Grugni, Graziano; Tringali, Gabriella; Agosti, Fiorenza; Sartorio, Alessandro

2015-01-01

Fat-free mass (FFM) is lower in obese subjects with Prader-Willi syndrome (PWS) than in obese subjects without PWS. FFM prediction equations developed in non-PWS subjects may, thus, not work in PWS subjects. To test whether the estimation of FFM from bioelectrical impedance analysis (BIA) in PWS subjects requires population-specific equations. Using dual-energy X-ray absorptiometry, this study measured FFM in 27 PWS and 56 non-PWS obese women and evaluated its association with the impedance index at 50 kHz (ZI50), i.e. the ratio between squared height and whole-body impedance at 50 kHz. At the same level of ZI50, PWS women had a lower FFM than non-PWS women. However, when PWS-specific equations were used, FFM was accurately estimated at the population level. An equation employing a dummy variable coding for PWS status was able to explain 85% of the variance of FFM with a root mean squared error of 3.3 kg in the pooled sample (n = 83). Population-specific equations are needed to estimate FFM from BIA in obese PWS women.

Comparison of Body Fat Results from 4 Bioelectrical Impedance Analysis Devices vs. Air Displacement Plethysmography in American Adolescent Wrestlers

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Melissa M. Montgomery

2017-10-01

Full Text Available Background: Accurate and accessible methods of body composition are necessary to ensure health and safety of wrestlers during competition. The most valid and reliable instruments are expensive and relatively inaccessible to high school wrestlers; therefore, more practical technology is needed. Objective: To compare body fat percentage (BF% results from 4 bioelectrical impedance analysis (BIA devices to those from air displacement plethysmography (ADP in adolescent wrestlers. Methodology: 134 adolescent male and female wrestlers (1.72±0.9 m, 66.8±14.3 kg, 15.6±1.1 yrs. were tested for hydration and then completed 4 body composition tests with different BIA devices and one with Bod Pod. Relative and absolute agreement were assessed between each BIA device and ADP on a single day. Results: When compared with ADP, all devices demonstrated excellent reliability (ICC (2,1 range: 0.88-0.94, but questionable measurement error (SEM range: 2.3-3.6 %BF. Bland-Altman plots revealed that each bioelectrical impedance device we tested over-estimated body fat percent in high school wrestlers (range: 0.8-3.6 %BF and demonstrated wide 95% limits of agreement (range: 15.0-20.8 %BF compared to ADP. Conclusions: The devices investigated demonstrated reasonable measurement accuracy. However, wide margins of error of each device were noted. Caution should be taken when assessing adolescent wrestlers with lower amounts of body fat, as it may result in failing to identify those who do not meet the minimum body fat percentage for competition. The governing bodies should use the research data in the decision-making process regarding appropriate devices for use in their weight management programs.

The optimal growth hormone replacement dose in adults, derived from bioimpedance analysis.

Science.gov (United States)

de Boer, H; Blok, G J; Voerman, B; de Vries, P; Popp-Snijders, C; van der Veen, E

1995-07-01

The prevalence of clinical signs and symptoms related to fluid retention is high in most studies evaluating the efficacy of GH treatment in GH-deficient (GHD) adults. This may be a consequence of supraphysiological GH replacement. To examine whether fluid retention is a dose-related phenomenon, we evaluated the impact of various GH substitution doses on body fluid status in 46 GHD men participating in a 1-yr, double blind, and placebo-controlled study. The patients were randomized to receive either placebo (n = 13) or GH in a dose of 1 (n = 11), 2 (n = 10), or 3 (n = 12) IU/m2.day, respectively. Treatment was started at one third of the predetermined dose and was subsequently increased by another third every month until the maintenance dose was reached. Tissue hydration was assessed by means of electrical impedance measurements. Normal values were obtained from 128 age- and sex-matched controls. In the untreated GHD state, whole body resistance was abnormally high (observed, 642 +/- 82 omega; predicted, 550 +/- 31 omega; P Regression analysis of the pooled data showed that GH replacement in a dose of 1.10 IU/m2.day (95% confidence interval, 0.85-1.45 IU/m2.day) resulted in a normalization of whole body resistance. In conclusion, GH replacement therapy in adults rapidly corrects the preexisting deficit in ECW. This rehydration process is dose dependent and may result in a substantial weight gain.(ABSTRACT TRUNCATED AT 400 WORDS)

Can abdominal bioelectrical impedance refine the determination of visceral fat from waist circumference?

International Nuclear Information System (INIS)

Watson, S; Blundell, H L; Evans, W D; Griffiths, H; Newcombe, R G; Rees, D A

2009-01-01

Ryo et al (2005 Diabetes Care 28 451–3) reported a new method for measuring the visceral fat area (VFA) by combining abdominal bioelectrical impedance analysis (BIA) with measurement of waist circumference (WC), but very few methodological details were provided. Furthermore, the study did not test the use of WC alone as an indicator of VFA even though others had previously reported a strong correlation. We sought to determine the optimal measurement technique and analysis for measuring VFA by abdominal BIA and WC. 18 volunteers (age 23–64 years) underwent measurement of WC, abdominal impedance (Bodystat 500 four-electrode system) and a single cross-sectional CT scan at the umbilicus. VFA derived using WC 3 and measurements of abdominal impedance from electrode pairs sited at the flank predicted the value of VFA measured by CT with correlation r = 0.904 (p 1.9 alone, without involving BIA at all, provided a similar correlation (r = 0.923). Our small preliminary study shows that abdominal BIA is potentially a practicable non-invasive technique for measurement of VFA but casts doubt on whether it adds any value to the use of WC alone. Larger studies are now required to test this finding. (note)

Fat mass to fat-free mass ratio reference values from NHANES III using bioelectrical impedance analysis.

Science.gov (United States)

Xiao, J; Purcell, S A; Prado, C M; Gonzalez, M C

2017-10-06

Low fat-free mass (FFM) or high fat mass (FM) are abnormal body composition phenotypes associated with morbidity. These conditions in combination lead to worse health outcomes, and can be identified by a high FM/FFM ratio. Here, we developed sex, age, and body mass index (BMI) stratified, population-based FM/FFM reference values using bioelectrical impedance analysis (BIA) measurements. White, non-Hispanic individuals aged 18-90 years old with data for weight, stature and BIA resistance measures from the third National Health and Nutrition Examination Survey (NHANES) III were included. Previously validated and sex-specific BIA prediction equations were used to calculate FM and FFM. FM/FFM values were generated at 5th, 50th and 95th percentiles for each sex, age (18-39.9, 40-59.9, 60-69.9 and 70-90 years), and BMI category (underweight, normal weight, overweight, class I/II and class III obesity). A total of 6372 individuals who had estimated FM and FFM values were identified (3366 females, 3006 males). Median values of FM/FFM were 0.24 and 0.40 for young (≤39.9 years) males and females with normal BMI, and 0.34 for males and 0.59 for females who were overweight. For elderly individuals aged >70 years, median FM/FFM for males and females were respectively 0.28 and 0.45 for those with normal BMI, and 0.37 and 0.61 for those in the overweight category. These FM/FFM reference values provide information on body composition characteristics that account for age, sex and BMI, which can be useful to identify individuals at risk for body composition abnormalities. Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Efeitos do ultra-som terapêutico sobre o crescimento longitudinal do fêmur e da tíbia em ratos Effects of therapeutic ultrasound on longitudinal growth of the femur and tibia in rats

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Alfredo Alcantara Barreto

2011-01-01

Full Text Available OBJETIVO: Estudar efeitos do ultra-som terapêutico sobre o crescimento do fêmur e da tíbia, em ratos jovens. MÉTODO: Ratus norvegicus com quatro semanas de vida, machos, totalizando 115 animais, divididos em quatro grupos, foram submetidos ao ultra-som terapêutico (0,8 MHz, cabeçote fixo, pulso contínuo, por dez minutos, durante dez dias, na face medial do joelho direito, nas potências de 0,0 W/cm2 (grupo controle, 0,5 W/cm2 (grupo G2, 1,0 W/cm2 (grupo G3, e 1,5 W/cm2 (grupo G4. Lâminas histológicas da epífise, placa de crescimento e metáfise e as medidas dos comprimentos do fêmur e da tíbia foram estudadas na sexta, décima terceira e vigésima sexta semanas de vida. Os dados foram submetidos à análise de variância - fatorial inteiramente aleatorizado. RESULTADO: Nenhuma alteração estatística do crescimento ósseo foi estabelecida entre quaisquer dos três grupos tratados e o grupo controle. Entretanto, alterações sugestivas de diminuição do crescimento do fêmur e da tíbia de G4 em relação a G2 e G3, foram evidenciadas. No grupo G4 alterações histopatológicas como necroses celulares e neoformação óssea, pós-necrose, foram encontradas. CONCLUSÃO: Quando comparados os grupos tratados com o grupo controle, não há evidência estatística de estímulo ou inibição ao crescimento ósseo pela aplicação do ultra-som terapêutico. Nível de Evidência: Nível II, estudo coorte transversal.OBJECTIVES: To determine the effects of ultrasound therapy on the femur and tibia growth in young rats. METHOD: Four-week-old male Ratus Norvegicus totaling 115 animals, divided into four groups, were submitted to ultrasound therapy (0.8 MHz, fixed tube head, continuous pulse, for 10 minutes, once a day, ten times on the medial face of the right knee, with powers of 0.0 W/cm2 (group G1, 0.5 W/cm2 (group G2, 1.0 W/cm2 (group G3, and 1.5 W/cm2 (group G4. Histological slides of the epiphysis, growth plate and metaphysis and the

Multivariate analysis of electrical impedance spectra for relaxed and contracted skeletal muscle

International Nuclear Information System (INIS)

Zagar, T; Krizaj, D

2008-01-01

Four-electrode impedance spectra of relaxed and contracted muscle biceps brachii were analyzed in an adult human subject over the frequency range from 300 Hz to 75 kHz. A feasibility of the principal component analysis of bioimpedance measurement for the evaluation of skeletal muscle contractile state was examined. The principal components score plots show a data grouping of the impedance spectra from the two muscle groups. The classification was performed using a soft independent modeling of class analogy (SIMCA) method. The data set comprised 32 samples (16 samples of contracted muscle and 16 samples of relaxed muscle). The leave-one-out test of the classification yields about 80% of correctly classified samples (11 samples for contracted and 15 samples for relaxed muscle)

Relationship between body fat percentage determined by bioelectrical impedance analysis and metabolic risk factors in Syrian male adolescents (18–19 years

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Al-Bachir Mahfouz

2017-03-01

Full Text Available The association between increasing obesity and metabolic syndrome among adolescent and the adverse consequences in adulthood including type-2 diabetes and coronary heart disease is well documented. The main objectives of this study were to evaluate the major metabolic risk factors and some clinical important parameters in Syrian male adolescents (18-19 years old, and to assess the correlations between BF% determined by BIA-man prediction equation and metabolic risk factors in the same group. The correlations between body fat percentage (BF% based on BIA-man predictive equations, blood pressure, fasting blood sugar (FBS, cholesterol (Chol, low density lipoprotein cholesterol (LDL-C, high density lipoprotein cholesterol (HDL-C, triglycerides (TG, Hematocrit (Ht, and hemoglobin (Hb in 1596 healthy Syrian adolescents aged 18-19 years and the mean values of these parameters were examined. Data showed that, DBP, Chol, TG, LDL and TG/HDL-C were significantly (p<0.05 higher in overweight and obese subjects in compression to normal weight cases. Whereas, SBP, FBS and Ht were significantly (p<0.05 higher in obese subjects in compression to normal weight. However, all measured variable related to metabolic syndrome risk factors increased with increasing the BF% determined by BIA-man. The present study suggests that % BF by BIA-man is a good predictor of metabolic risks factors for Syrian adolescents.

Single- and multi-frequency bioelectrical impedance analyses to analyse body composition in maintenance haemodialysis patients: comparison with dual-energy x-ray absorptiometry

International Nuclear Information System (INIS)

Donadio, C; Halim, A Ben; Caprio, F; Grassi, G; Khedr, B; Mazzantini, M

2008-01-01

The aim of this study was to evaluate the adequacy of single-frequency (sf-BIA) and multi-frequency bioelectrical impedance analyses (mf-BIA), in comparison with dual-energy x-ray absorptiometry (DXA), to evaluate body composition in maintenance haemodialysis (MHD) patients. Body composition of 27 adult MHD patients (9 f, 18 m), BMI 17.5–34.4 kg m −2 , was examined with DXA and BIA, with two different sf-BIA and 1 mf-BIA analysers. Biochemical markers of nutritional status and adequacy of dialytic treatment were also determined. Fat mass (FM) estimated by the different BIA analysers was found to be slightly but significantly higher than FM measured by DXA. In contrast, fat-free mass (FFM) obtained with BIA was found to be slightly but significantly lower than FFM DXA. No significant differences were found between LBM-DXA (that is FFM-DXA minus bone mass) and the different FFM BIA. The lowest mean prediction error versus DXA values was found with sf1BIA. In any case, a close correlation was found between all BIA values and DXA values, particularly for FFM. Furthermore, FFM and LBM results were significantly correlated with serum creatinine, which in MHD patients is an indicator of muscle mass. These results indicate that BIA can be used to evaluate body composition in MHD patients

Effect of the ethinylestradiol/norelgestromin contraceptive patch on body composition. Results of bioelectrical impedance analysis in a population of Italian women

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Bruni Vincenzina

2008-08-01

Full Text Available Abstract Background As weight gain is one of the most frequently cited reasons for not using and for discontinuing hormonal contraceptives, in an open-label, single-arm, multicentre clinical study we evaluated the effect of the ethinylestradiol/norelgestromin contraceptive patch (EVRA, Janssen-Cilag International, Belgium on body composition using bioelectrical impedance analysis (BIA. Methods Body weight and impedance vector components (resistance (R and reactance (Xc, at 50 kHz frequency, Akern-RJL Systems analyzer were recorded before entry, after 1, 3 and 6 months in 182 Italian healthy women aged 29 yr (18 to 45, and with BMI 21.8 kg/m2 (16 to 31. Total body water (TBW was estimated with a BIA regression equation. Vector BIA was performed with the RXc mean graph method and the Hotelling's T2 test for paired and unpaired data. Results After 6 months body weight increased by 0.64 kg (1.1% and TBW increased by 0.51 L (1.7%. The pattern of impedance vector displacement indicated a small increase in soft tissue hydration (interstitial gel fluid. Body composition changes did not significantly differ among groups of previous contraceptive methods. Arterial blood pressure did not significantly change over time. Conclusion After 6 months of treatment with the ethinylestradiol/norelgestromin contraceptive patch we found a minimal, clinically not relevant, increase in body weight less than 1 kg that could be attributed to an adaptive interstitial gel hydration. This fluctuation is physiological as confirmed by the lack of any effect on blood pressure. This could be useful in increasing women's choice, acceptability and compliance of the ethinylestradiol/norelgestromin contraceptive patch.

Estabilidade aeróbia de silagens de capim-mombaça tratadas com Lactobacillus buchneri Aerobic stability of mombaça grass silages treated with Lactobacillus buchneri

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Carla Luiza da Silva Ávila

2009-05-01

Full Text Available Objetivou-se avaliar o efeito da adição de duas cepas de Lactobacillus buchneri sobre a estabilidade aeróbia de silagens de capim-mombaça. O experimento foi conduzido em delineamento inteiramente casualizado com três repetições, em esquema de parcelas subdivididas no tempo, de modo que os tratamentos (silagens sem inoculantes e com inoculante experimental e comercial foram aleatorizados nas parcelas e os tempos de avaliação aeróbia das silagens (0, 2, 8 ou 10 dias após a abertura dos silos nas subparcelas. Após 90 dias de armazenamento, os silos foram abertos e amostras de aproximadamente 2,5 kg foram retiradas para avaliação da estabilidade aeróbia com base na temperatura de cada amostra. As mudanças químicas e microbiológicas foram avaliadas. Após abertura dos silos, verificou-se aumento nas populações de bactérias do ácido lático, leveduras e fungos filamentosos. Houve aumento nos valores de pH resultante da redução da concentração dos ácidos orgnicos e de aumentos dos teores de matéria seca e proteína bruta. A adição de L. buchneri às silagens melhorou sua estabilidade, enquanto a silagem sem inoculante apresentou estabilidade de 55 horas. As silagens inoculadas não ultrapassaram essa temperatura limite em um período de 10 dias. A melhoria da estabilidade foi ocasionada pela associação de altas concentrações de cido acético ao ácido propiônico e pela menor concentração de ácido lático no momento de abertura, o que inibiu a proliferação de fungos filamentosos e leveduras após abertura dos silos.This study aimed to evaluate the effect of the addition of two L. buchneri strains on the aerobic stability of the Mombaça grass silages. The experiment was carried out in a completely randomized design with three replicates in split-plot in time scheme, so that the treatments (silages without inoculant and with experimental or commercial inoculants were randomized on plot and in times of aerobic

[Improvement of rosacea treatment based on the morphological and functional features of the skin].

Science.gov (United States)

Tsiskarishvili, N V; Katsitadze, A G; Tsiskarishvili, Ts I

2013-10-01

Rosacea - a widespread disease sometimes aleak with severe complications, mainly affecting the skin. Irrational and inadequate treatment leads to chronicity of diseases and psychosocial disadaptation of patients. Lately, a clear upward trend in the number of patients in whom in the process of complex treatment manifestations (with the varying degrees of severity) of impaired barrier function of the skin are observed and they need the protection and restoration of the damaged stratum corneum. In patients with rosacea in order to study the function of the facial skin's horny layer we used the skin analyzer BIA (bioimpedance analysis, which in duration of 6 seconds determines the moisture content, oiliness and the softness of the skin) and significant deviations from the norm (decrease in moisture content, fatness and increased roughness) was revealed. These changes were most clearly pronounced in patients with steroid rosacea. To restore the skin barrier the drug "Episofit A" (Laboratory of Evolutionary Dermatology, France) has been used (1-2 times a day for 6 weeks). Evaluation of treatment efficacy was conducted every 2 weeks by means of a scale from 0 to 5 for parameters of dryness, erythema, peeling and expression of subjective feelings. In accordance with received results, using of Episofit A emulsion, especially on the baсkground of long-term treatment with topical steroids, had a pronounced therapeutic effect. Thus, treatment of patients with consideration of morphological and functional features of facial skin, helps to improve the results traditional therapy, and the drug is highly effective means of the new direction in skin care - corneotherapy aimed to reconstruct and protect damaged stratum corneum.

The Effects of Short-Term Intensive Exercise on Levels of Liver Enzymes and Serum Lipids in Kick Boxing Athletes

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Ömer Kaynar

2016-03-01

Full Text Available Objective: In this study, it was aimed to evaluate the ef­fects of short-term intensive exercise on liver enzymes and serum lipid levels with kick boxing athletes. Methods: 23 voluntary athletes who were between the ages of 15-46 and who engaged in kick–boxing have tak­en place this study. Athletes were made to do 45 minutes of warming-up, breathing, and stretching and 50 minutes of technical and tactical practices and then they were made to do a training match, which is equal to a 2 min­utes 3 circuits (1 minute rest kick-box match. In venous blood samples which were taken from athletes before and after training, aspartate aminotransferase (AST, alanine aminotransferase (ALT, alkaline phosphatase (ALP and gamma glutamine transpeptidase (GGT, enzyme activity and total cholesterol, high-density lipoprotein-cholesterol (HDL-C, low density lipoprotein-cholesterol (LDL-C and triglycerides serum levels were analyzed via spectropho­tometric method in Beckman Coulter AU 5800 auto ana­lyzer. Body composition measurements of athletes were made with Tanita TBF 300 brand device, which works with bio-impedance analysis (BIA system. Results: As a result of our study, statistically increases in serum ALT, AST, ALP and GGT enzyme activities and in serum total cholesterol, HDL-C and LDL-C levels were detected following short-term intensive exercise, but no significant difference was observed in TG levels after in­tensive exercise. Conclusion: The blows to the abdomen during kickbox­ing sports competitions result in increased liver enzymes and increased serum lipids may occur to meet energy de­mand of the body during exercise.

Genetic analysis and fine mapping of a rice brown planthopper (Nilaparvata lugens Stål) resistance gene bph19(t).

Science.gov (United States)

Chen, J W; Wang, L; Pang, X F; Pan, Q H

2006-04-01

Genetic analysis and fine mapping of a resistance gene against brown planthopper (BPH) biotype 2 in rice was performed using two F(2) populations derived from two crosses between a resistant indica cultivar (cv.), AS20-1, and two susceptible japonica cvs., Aichi Asahi and Lijiangxintuanheigu. Insect resistance was evaluated using F(1) plants and the two F(2) populations. The results showed that a single recessive gene, tentatively designated as bph19(t), conditioned the resistance in AS20-1. A linkage analysis, mainly employing microsatellite markers, was carried out in the two F(2) populations through bulked segregant analysis and recessive class analysis (RCA), in combination with bioinformatics analysis (BIA). The resistance gene locus bph19(t) was finely mapped to a region of about 1.0 cM on the short arm of chromosome 3, flanked by markers RM6308 and RM3134, where one known marker RM1022, and four new markers, b1, b2, b3 and b4, developed in the present study were co-segregating with the locus. To physically map this locus, the bph19(t)-linked markers were landed on bacterial artificial chromosome or P1 artificial chromosome clones of the reference cv., Nipponbare, released by the International Rice Genome Sequencing Project. Sequence information of these clones was used to construct a physical map of the bph19(t) locus, in silico, by BIA. The bph19(t) locus was physically defined to an interval of about 60 kb. The detailed genetic and physical maps of the bph19(t) locus will facilitate marker-assisted gene pyramiding and cloning.

Post-Mortem Evaluation of Pathological Lesions in European Bison (Bison Bonasus in the Białowieża Primeval Forest Between 2008 and 2013

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K. Krzysiak Michał

2014-10-01

Full Text Available The study presents the analysis of the findings of 234 post-mortem examinations on free-ranging and captive European bison selectively culled or having fallen between 2008 and 2013 in Białowieża Primeval Forest. Pneumonia, emphysema, nephritis, bodily traumas, and intestinal lesions were observed in 106 (45.3%, 77 (32.9%, 82 (35.0%, 68 (29.1%, and 56 (23.9% animals respectively and were the most common pathological changes. Almost half of all males (66 out of 140; 47.1% tested showed some pathological changes of prepuce and penis, described as posthitis or balanoposthitis. Infection with liver fluke (Fasciola hepatica and lungworm (Dictyocaulus viviparus was observed macroscopically in 114 (48.7% and 80 (32.9% bison respectively. F. hepatica prevalence was associated with the emergence of other liver changes such as hepatitis and cirrhosis (P < 0.001. Similarly, the prevalence of D. viviparus coincided with pneumonia (P = 0.001, changes in the upper respiratory tract (P = 0.04, and emphysema (P < 0.001. Hepatitis, infection with F. hepatica, and pathological lesions in the male and female reproductive tracts were associated with the animals’ age. Mechanical injuries, caused by other bison or less commonly by traffic accidents, were the most common cause of death of bison below six months of age. Most pathological changes were significantly more frequent in the selectively culled animals in comparison with the ones having fallen, which confirms the desirability of elimination as a tool to improve the health and welfare of the bison population and limit the number of reservoirs of invasive and possibly infectious diseases.

Modalities for assessing the nutritional status in patients with diabetes and cancer.

Science.gov (United States)

Clemente, G; Gallo, M; Giorgini, M

2018-05-30

Epidemiological data have shown that an increased body mass index (BMI) is associated with a higher risk of various cancers, especially in obese diabetic patients. However, oncologic patients often present nutritional alterations that can worsen their prognosis. The aim of this review is to propose the use of cheaper and easy to use tools to assess the nutritional status of patients with cancer with altered glucose metabolism. Based on a literature review, we propose anthropometric measures to classify the degree of malnutrition. Moreover, the Karnofsky Performance Status (KPS) and the Eastern Cooperative Oncology Group's performance index (ECOG) are useful to assess the functional status of the body; the achievement of nutritional needs can be analysed with the PG-SGA questionnaire, while the quality of life can be investigated using the DTSQ, SF36, EQ-5D questionnaires and the Edmonton Symptom Assessment System. Pre-albumin dosage and lymphocyte count are proposed as nutritional parameters. The degree of hydration can be evaluated through the Bio-Impedance Test (BIA), and energy intake through the dairy food diary, which considers the type of nutrition and the consistency of the meals. It is possible to use a score for each tool used, which is useful to plan an adequate nutritional intervention. Copyright © 2018 Elsevier B.V. All rights reserved.

Bioimpedance Spectroscopy

DEFF Research Database (Denmark)

Klösgen, Beate; Rümenapp, Christine; Gleich, Bernhard

2011-01-01

causes relaxation processes with characteristic contributions to the frequency-dependent complex dielectric constant. These dipolar relaxations were initially described by Debye (Polare Molekeln 1929). They are the basis of impedance spectroscopy (K’Owino and Sadik Electroanalysis 17(23):2101–2113, 2005...

Bioelectrical impedance analysis for bovine milk: Preliminary results

Science.gov (United States)

Bertemes-Filho, P.; Valicheski, R.; Pereira, R. M.; Paterno, A. S.

2010-04-01

This work reports the investigation and analysis of bovine milk quality by using biological impedance measurements using electrical impedance spectroscopy (EIS). The samples were distinguished by a first chemical analysis using Fourier transform midinfrared spectroscopy (FTIR) and flow citometry. A set of milk samples (100ml each) obtained from 17 different cows in lactation with and without mastitis were analyzed with the proposed technique using EIS. The samples were adulterated by adding distilled water and hydrogen peroxide in a controlled manner. FTIR spectroscopy and flow cytometry were performed, and impedance measurements were made in a frequency range from 500Hz up to 1MHz with an implemented EIS system. The system's phase shift was compensated by measuring saline solutions. It was possible to show that the results obtained with the Bioelectrical Impedance Analysis (BIA) technique may detect changes in the milk caused by mastitis and the presence of water and hydrogen peroxide in the bovine milk.

Aerobic stability of triticale silage in single culture or in mixtures with oat and/or legumes Estabilidade aeróbia de silagens de triticale em cultivo exclusivo ou em misturas com aveia e/ou leguminosas

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Valter Harry Bumbieris Junior

2010-11-01

Full Text Available The objective of the present study was to evaluate the aerobic stability and losses during the fermentation process of triticale silages in single crop or in mixtures with oats and/or legumes. The following crops were used for silage production: triticale (X. Triticosecale Wittimack, triticale intercropped with forage pea (Pisum arvense and triticale intercropped with oats (Avena strigosa Schreb, forage pea and vetch (Vicia sativa. The dry matter content and its recovery did not differ among the silages. Buffer capacity was higher for tricale silage intercropped with oats, forage pea and vetch(88.67 m eq. NaOH/100 g DM followed by triticale intercropped with forage pea (80.80 m eq. NaOH/100 g DM. Electric conductivity values were higher in the intercropped triticale silages. Triticale silage presented the lowest temperatures observed in the silos, and the silages of intercropped triticale silages presented higher heat retention and higher pH values. Silage of triticale intercropped with oats and legumes presented lower aerobic stability but it did not reduce the aerobic stability of the total feed. Dry matter recovery during storage and in stability evaluations in aerobiosis is similar among the silages.O objetivo neste trabalho foi avaliar a estabilidade aeróbia e as perdas durante o processo de fermentação de silagens de triticale em cultivo exclusivo ou em misturas com aveia e/ou leguminosas. As culturas utilizadas para produção das silagens foram: triticale (X. Triticosecale Wittimack; triticale em consórcio com ervilha-forrageira (Pisum arvense; e triticale em consórcio com aveia (Avena strigosa Schreb, ervilha-forrageira e ervilhaca (Vicia sativa. O teor de matéria seca e a recuperação de matéria seca não diferiram entre as silagens. A capacidade tampão foi maior para a silagem de triticale cultivado em consórcio com aveia, ervilha-forrageira e ervilhaca (88,67 m eq. NaOH/100 g de MS, seguida da silagem de triticale cultivado

Body Mass Index assessment of institutionalized aged people without cognitive impairment using clinical and nutritional factors

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María del Mar Ruperto López

2016-12-01

Full Text Available Introduction: Overweight and obesity are recognized mortality risk factors in the general population. The aim of the study was to analyse the phenotypic distribution of body mass index (BMI, and to identify the prevalence of malnutrition and clinical and nutritional factors related to BMI in autonomous institutionalized elders. Material and Methods: Cross-sectional and descriptive study in 104 institutionalized aged people (73% female, mean of age 86.4 [±6.2] years and time on institutionalization 25.7 [±21.7] months. Mini-Nutritional Assessment (MNA, anthropometric measures and laboratory parameters were used for nutritional assessment. Bioimpedance analysis (BIA-101; RJL-System was used for body composition analysis. The sample was classified into BMI tertiles (Tn: T1=<26.2kg/m2; T2=26.3-29.7kg/m2; and T3=≥29.8kg/m2. Results: The phenotypic distribution of BMI was: overweight 51% and, prevalence of obesity 29.8%. Mean of BMI: 28.3 (±4.6 kg/m2. Nutritional risk or malnutrition were 60.6% and 11.5%, respectively in the sample. The tertiles of BMI showed significant differences with: mid-arm muscle circumference, triceps-skinfold thickness, total body water (TBW (all, p<0.001. Subjects into T1 had significantly higher nutritional risk or malnutrition compared with T2 and T3 counterparts (p=0.015. Waist-circumference, calf-circumference (at least, p<0.01, and TBW (p<0.001 were independent predictors of BMI in the linear regression analysis (R2=0.52. Conclusions: Overweight and obesity measured by BMI is not an exclusion criterion of malnutrition in the geriatric population. Nutritional screening by MNA and the conjoint use of clinical-nutritional parameters are useful for identifying at nutritional risk or malnutrition. Further studies are needed to define the potential nutritional risk factors associated with BMI in autonomous institutionalized aged.

Volume Estimates in Chronic Hemodialysis Patients by the Watson Equation and Bioimpedance Spectroscopy and the Impact on the Kt/Vurea calculation.

Science.gov (United States)

Noori, Nazanin; Wald, Ron; Sharma Parpia, Arti; Goldstein, Marc B

2018-01-01

Accurate assessment of total body water (TBW) is essential for the evaluation of dialysis adequacy (Kt/V urea ). The Watson formula, which is recommended for the calculation of TBW, was derived in healthy volunteers thereby leading to potentially inaccurate TBW estimates in maintenance hemodialysis recipients. Bioimpedance spectroscopy (BIS) may be a robust alternative for the measurement of TBW in hemodialysis recipients. The primary objective of this study was to evaluate the accuracy of Watson formula-derived TBW estimates as compared with TBW measured with BIS. Second, we aimed to identify the anthropometric characteristics that are most likely to generate inaccuracy when using the Watson formula to calculate TBW. Finally, we derived novel anthropometric equations for the more accurate estimation of TBW. This was a cross-sectional study of prevalent in-center HD patients at St Michael's Hospital. One hundred eighty-four hemodialysis patients (109 men and 75 women) were evaluated in this study. Anthropometric measurements including weight, height, waist circumference, midarm circumference, and 4-site skinfold (biceps, triceps, subscapular, and suprailiac) thickness were measured; fat mass was measured using the formula by Durnin and Womersley. We measured TBW by BIS using the Body Composition Monitor (Fresenius Medical Care, Bad Homburg, Germany). We used the Bland-Altman method to calculate the difference between the TBW derived from the Watson method and the BIS. To derive new equations for TBW estimation, Pearson's correlation coefficients between BIS-TBW (the reference test) and other variables were examined. We used the least squares regression analysis to develop parsimonious equations to predict TBW. TBW values based on the Watson method had a high correlation with BIS-TBW (correlation coefficients = 0.87 and P Watson formula overestimated TBW by 5.1 (4.5-5.8) liters and 3.8 (3.0-4.5) liters, in men and women, respectively. Higher fat mass and waist

Tratamento da pseudartrose infectada da tíbia pelo método de Ilizarov: técnica do encurtamento agudo com subseqüente alongamento Treatment of infected pseudoarthrosis of the tibia by Ilizarov's method: technique using acute compression and subsequent distraction

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Jorge Luiz Borges

2007-09-01

Full Text Available OBJETIVO:Comprovar a eficácia do tratamento da pseudartrose infectada da tíbia pelo método de Ilizarov, utilizando a técnica do encurtamento agudo do foco da pseudartrose com posterior alongamento ósseo. MÉTODOS: Foram estudados 20 pacientes adultos portadores de pseudartrose unilateral infectada da tíbia, tratados no período entre novembro de 1993 e setembro de 2000. No pós-operatório, os pacientes foram avaliados quanto a dor, necessidade de órtese, avaliação da mobilidade articular, retorno às atividades normais do dia-a-dia e/ou do trabalho, consolidação da pseudartrose, cura da infecção, existência de deformidades ósseas, discrepância no comprimento dos membros e consolidação óssea na área do regenerado ósseo. RESULTADOS: Os resultados funcionais foram: excelentes em 10 pacientes (50%, bons em oito (40%, regulares em um (5% e ruins em um paciente (5%. O tempo de consolidação da pseudartrose, do segmento ósseo alongado e o tempo de uso do fixador foram proporcionais à extensão da perda óssea. CONCLUSÃO: O método de Ilizarov, associado ao encurtamento agudo com subseqüente alongamento ósseo, mostrou-se eficaz para o tratamento da pseudartrose infectada da tíbia.OBJECTIVE: To verify the effectiveness of treating the infected pseudoarthrosis of the tibia by Ilizarov's method using the technique of acute compression of the focus of pseudoarthrosis with later bone distraction. METHODS: 20 adult patients with unilateral infected pseudoarthrosis of the tibia treated from November 1993 to September 2000 were studied. In the postoperative period, the patients were evaluated for pain, orthesis requirement, joint mobility, return to daily life activities and/or to work, union of the pseudoarthrosis, cure of the infection, presence of bone deformities, discrepancy in limb length, and bone union in the bone regenerate area. RESULTS: Functional results were: excellent in 10 patients (50%, good in eight (40%, regular in

Charakterystyka etiologiczna udarów mózgu leczonych w Klinice Neurologii UM w Białymstoku z analizą czynników ryzyka

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Anna Syta-Krzyżanowska

2010-03-01

Full Text Available Wstęp: W przeprowadzonych w Polsce badaniach epidemiologicznych stwierdzono utrzymujący się od kilkunastu lat wysoki współczynnik zapadalności na pierwszy w życiu udar mózgu, wzrastający wykładniczo z wiekiem oraz połączony z wciąż dużą śmiertelnością. Poznanie czynników ryzyka oraz wprowadzenie profilaktyki może istotnie zmniejszyć powyższe wskaźniki. Celem pracy było przeprowadzenie analizy epidemiologicznej pacjentów z udarem mózgu hospitalizowanych na Pododdziale Udarowym Kliniki Neurologii USK w Białymstoku. Uwzględniono w szczególności etiologię z czynnikami ryzyka oraz śmiertelnością w zależności od wieku i płci chorych. Materiał i metody: Rozpatrzono wszystkie przypadki pacjentów hospitalizowanych w Klinice Neurologii USK w Białymstoku z powodu udaru mózgu w ciągu pełnego roku kalendarzowego. Posłużono się ankietami prowadzonymi w ramach Narodowego Programu Profilaktyki i Leczenia Chorób Sercowo-Naczyniowych (POLKARD. Obliczenia statystyczne wykonywano przy użyciu programu Statistica w wersji 8.0. Wyniki: Przeanalizowano wyniki 408 pacjentów, w tym 185 (45,3% kobiet oraz 223 (54,7% mężczyzn z rozpoznanym: krwotokiem podpajęczynówkowym – 6,9%, krwotokiem śródmózgowym – 12,5% oraz udarem niedokrwiennym – 80,6%. Etiologię zatorową pochodzenia sercowego zdiagnozowano u 39,4%, zakrzep dużych naczyń u 35%, natomiast udar zatokowy u 11,6% pacjentów. Najczęstszym czynnikiem ryzyka udaru niedokrwiennego mózgu było nadciśnienie tętnicze (81,2%, następnie migotanie przedsionków i choroba niedokrwienna serca (38%. Zmarło 11,6% chorych z udarem niedokrwiennym mózgu oraz 21,5% z udarem krwotocznym. Średnia śmiertelność wyniosła 13,5%. Wnioski: Najczęstszym czynnikiem ryzyka udaru mózgu było nadciśnienie tętnicze, które szczególnie często współwystępowało z dodatkowym czynnikiem ryzyka udaru niedokrwiennego mózgu. Prowadzenie leczenia udaru mózgu w pododdzia

Geometric Methods in Physics XXXV

CERN Document Server

Odzijewicz, Anatol; Previato, Emma

2018-01-01

This book features a selection of articles based on the XXXV Białowieża Workshop on Geometric Methods in Physics, 2016. The series of Białowieża workshops, attended by a community of experts at the crossroads of mathematics and physics, is a major annual event in the field. The works in this book, based on presentations given at the workshop, are previously unpublished, at the cutting edge of current research, typically grounded in geometry and analysis, and with applications to classical and quantum physics. In 2016 the special session "Integrability and Geometry" in particular attracted pioneers and leading specialists in the field. Traditionally, the Białowieża Workshop is followed by a School on Geometry and Physics, for advanced graduate students and early-career researchers, and the book also includes extended abstracts of the lecture series.

Reliability of blood pressure parameters for dry weight estimation in hemodialysis patients.

Science.gov (United States)

Susantitaphong, Paweena; Laowaloet, Suthanit; Tiranathanagul, Khajohn; Chulakadabba, Adhisabandh; Katavetin, Pisut; Praditpornsilpa, Kearkiat; Tungsanga, Kriang; Eiam-Ong, Somchai

2013-02-01

Chronic volume overload resulting from interdialytic weight gain and inadequate fluid removal plays a significant role in poorly controlled high blood pressure. Although bioimpedance has been introduced as an accurate method for assessing hydration status, the instrument is not available in general hemodialysis (HEMO) centers. This study was conducted to explore the correlation between hydration status measured by bioimpedance and blood pressure parameters in chronic HEMO patients. Multifrequency bioimpedance analysis was used to determine pre- and post-dialysis hydration status in 32 stable HEMO patients. Extracellular water/total body water (ECW/TBW) determined by sum of segments from bioimpedance analysis was used as an index of hydration status. The mean age was 57.9 ± 16.4 years. The mean dry weight and body mass index were 57.7 ± 14.5 kg and 22.3 ± 4.7 kg/m(2), respectively. Pre-dialysis ECW/TBW was significantly correlated with only pulse pressure (r = 0.5, P = 0.003) whereas post-dialysis ECW/TBW had significant correlations with pulse pressure, systolic blood pressure, and diastolic blood pressure (r = 0.6, P = 0.001, r = 0.4, P = 0.04, r = -0.4, and P = 0.02, respectively). After dialysis, the mean values of ECW/TBW, systolic blood pressure, mean arterial pressure, and pulse pressure were significantly decreased. ECW/TBW was used to classify the patients into normohydration (≤ 0.4) and overhydration (>0.4) groups. Systolic blood pressure, mean arterial pressure, and pulse pressure significantly reduced after dialysis in the normohydration group but did not significantly change in the overhydration group. Pre-dialysis pulse pressure, post-dialysis pulse pressure, and post-dialysis systolic blood pressure in the overhydration group were significantly higher than normohydration group. Due to the simplicity and cost, blood pressure parameters, especially pulse pressure, might be a simple reference for clinicians to determine hydration status in HEMO

Body composition measures of obese adolescents by the deuterium oxide dilution method and by bioelectrical impedance

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C.M.M. Resende

2011-11-01

Full Text Available The objectives of the present study were to describe and compare the body composition variables determined by bioelectrical impedance (BIA and the deuterium dilution method (DDM, to identify possible correlations and agreement between the two methods, and to construct a linear regression model including anthropometric measures. Obese adolescents were evaluated by anthropometric measures, and body composition was assessed by BIA and DDM. Forty obese adolescents were included in the study. Comparison of the mean values for the following variables: fat body mass (FM; kg, fat-free mass (FFM; kg, and total body water (TBW; % determined by DDM and by BIA revealed significant differences. BIA overestimated FFM and TBW and underestimated FM. When compared with data provided by DDM, the BIA data presented a significant correlation with FFM (r = 0.89; P < 0.001, FM (r = 0.93; P < 0.001 and TBW (r = 0.62; P < 0.001. The Bland-Altman plot showed no agreement for FFM, FM or TBW between data provided by BIA and DDM. The linear regression models proposed in our study with respect to FFM, FM, and TBW were well adjusted. FFM obtained by DDM = 0.842 x FFM obtained by BIA. FM obtained by DDM = 0.855 x FM obtained by BIA + 0.152 x weight (kg. TBW obtained by DDM = 0.813 x TBW obtained by BIA. The body composition results of obese adolescents determined by DDM can be predicted by using the measures provided by BIA through a regression equation.

Risk factors for type 2 diabetes and cardiovascular disease in Mexican adults from different socio-economic levels

Energy Technology Data Exchange (ETDEWEB)

Valencia Juillerat, M E; Gallegos, A C; Ballesteros, M N [Centro de Investigacion en Alimentacion y Desarrollo, Sonora (Mexico); and others

2002-07-01

Background: Obesity, type 2 diabetes and cardiovascular disease (CVD) are a major concern in many parts of the world. In Northern Mexico, these problems have been reported to be higher the in the rest of the country. Objective: To assess the different risk factors based on body status (body composition, body size, fat distribution) and lifestyle factors (diet and physical activity) for the development of type 2 diabetes and CVD in men and women from different socio-economic levels in north-west Mexico. Methods: Non probabilistic sample selection by invitation was used to recruit subjects, completing quotas by age groups, gender and socio-economic status. The study included 350 men and women, 20-84 years pertaining to low and high income groups from the city of Hermosillo, Sonora, Mexico. All subjects were measured for body weight, height, waist and hip circumferences, skinfolds, bioimpedance analysis (BIA), systolic and diastolic blood pressure SBP, DBP). Body mass index (BMI) and waist to hip ratio were calculated. An oral glucose tolerance test (OGTT) after a 12 hour fast was performed and blood samples were taken for analysis of insulin, leptin, total cholesterol, HDL, LDL-cholesterol and serum triglycerides. In 273 of the 350 subjects physical activity was studied by questionnaire. Activity was calculated as in categories of low, medium and high intensity and expressed as hours/day with respect to occupational and recreational activities. Physical activity level (PAL) was also calculated from the questionnaires. Body composition was investigated in more detail by air displacement plethysmography (densitometry) and by deuterium dilution in 200 subjects. Diet by 24 hour non-consecutive recalls in another sub-group of 135 male and female subjects. Statistical analysis was performed using NCSS statistical software using ANCOVA and regression procedures. Result: High levels of overweight (BMI >25) and obesity BMI>30) were found in this population group with 65 and

Sensitivity field distributions for segmental bioelectrical impedance analysis based on real human anatomy

International Nuclear Information System (INIS)

Danilov, A A; Rudnev, S G; V Vassilevski, Yu; Kramarenko, V K; Nikolaev, D V; Smirnov, A V; Salamatova, V Yu

2013-01-01

In this work, an adaptive unstructured tetrahedral mesh generation technology is applied for simulation of segmental bioimpedance measurements using high-resolution whole-body model of the Visible Human Project man. Sensitivity field distributions for a conventional tetrapolar, as well as eight- and ten-electrode measurement configurations are obtained. Based on the ten-electrode configuration, we suggest an algorithm for monitoring changes in the upper lung area.

Sensitivity field distributions for segmental bioelectrical impedance analysis based on real human anatomy

Science.gov (United States)

Danilov, A. A.; Kramarenko, V. K.; Nikolaev, D. V.; Rudnev, S. G.; Salamatova, V. Yu; Smirnov, A. V.; Vassilevski, Yu V.

2013-04-01

In this work, an adaptive unstructured tetrahedral mesh generation technology is applied for simulation of segmental bioimpedance measurements using high-resolution whole-body model of the Visible Human Project man. Sensitivity field distributions for a conventional tetrapolar, as well as eight- and ten-electrode measurement configurations are obtained. Based on the ten-electrode configuration, we suggest an algorithm for monitoring changes in the upper lung area.

analyzers in overweight/obese renal patients

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Mariusz Kusztal

2015-05-01

Full Text Available Bioelectrical impedance analysis (BIA is an affordable, non-invasive and fast alternative method to assess body composition. The purpose of this study was to compare two different tetrapolar BIA devices for estimating body fluid volumes and body cell mass (BCM in a clinical setting among patients with kidney failure.All double measurements were performed by multi-frequency (MF and single-frequency (SF BIA analyzers: a Body Composition Monitor (Fresenius Medical Care, Germany and BIA-101 (Akern, Italy, respectively. All procedures were conducted according to the manufacturers’ instructions (dedicated electrodes, measurement sites, positions, etc. Total body water (TBW, extracellular water (ECW, intracellular water (ICW and BCM were compared. The study included 39 chronic kidney disease patients (stage III-V with a mean age of 45.8 ± 8 years (21 men and 18 women who had a wide range of BMI [17-34 kg/m2 (mean 26.6 ±5].A comparison of results from patients with BMI <25 vs ≥25 revealed a significant discrepancy in measurements between the two BIA devices. Namely, in the group with BMI <25 (n=16 acceptable correlations were obtained in TBW (r 0.99; p<0.01, ICW (0.92; p<0.01, BCM (0.68; p<0.01, and ECW (0.96 p<0.05, but those with BMI ≥25 (n=23 showed a discrepancy (lower correlations in TBW (r 0.82; p<0.05, ICW (0.78; p<0.05, BCM (0.52; p<0.05, and ECW (0.76; p<0.01.Since estimates of TBW, ICW and BCM by the present BIA devices do not differ in patients with BMI <25, they might be interchangeable. This does not hold true for overweight/obese renal patients.

Ethnic variability in body size, proportions and composition in children aged 5 to 11 years: is ethnic-specific calibration of bioelectrical impedance required?

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Simon Lee

Full Text Available Bioelectrical Impedance Analysis (BIA has the potential to be used widely as a method of assessing body fatness and composition, both in clinical and community settings. BIA provides bioelectrical properties, such as whole-body impedance which ideally needs to be calibrated against a gold-standard method in order to provide accurate estimates of fat-free mass. UK studies in older children and adolescents have shown that, when used in multi-ethnic populations, calibration equations need to include ethnic-specific terms, but whether this holds true for younger children remains to be elucidated. The aims of this study were to examine ethnic differences in body size, proportions and composition in children aged 5 to 11 years, and to establish the extent to which such differences could influence BIA calibration.In a multi-ethnic population of 2171 London primary school-children (47% boys; 34% White, 29% Black African/Caribbean, 25% South Asian, 12% Other detailed anthropometric measurements were performed and ethnic differences in body size and proportion were assessed. Ethnic differences in fat-free mass, derived by deuterium dilution, were further evaluated in a subsample of the population (n = 698. Multiple linear regression models were used to calibrate BIA against deuterium dilution.In children < 11 years of age, Black African/Caribbean children were significantly taller, heavier and had larger body size than children of other ethnicities. They also had larger waist and limb girths and relatively longer legs. Despite these differences, ethnic-specific terms did not contribute significantly to the BIA calibration equation (Fat-free mass = 1.12+0.71*(height2/impedance+0.18*weight.Although clear ethnic differences in body size, proportions and composition were evident in this population of young children aged 5 to 11 years, an ethnic-specific BIA calibration equation was not required.

Pengembangan Bioelectrical Impedance Sebagai Control Commands Pengaturan Kecepatan Gerak Kursi Roda Dengan Metoda PID Controller

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Juli Sardi

2014-09-01

Full Text Available In the present study, bioimpedance signals of human body was utilized to control speed of a wheelchair movement. A bioimpedance is electrically passive part contained the body tissues. The research is one of alternative solutions for patients with paralysis of the upper and lower limb. Firstly, design of system of the research consisted of bioimpedance measuring instruments and a mechanical design of the wheelchair. Bioimpedance measurement was performed by injecting a sinusoidal current source of 0.5 mArms with a frequency of 50 kHz to muscle tissue (shoulder to obtain the output voltage in the range of 0-5 Vdc. With impulse and manual thresholding methods, the voltage signal was classified into several controls command to adjust the speed and direction of the wheelchair control based on PID Controller. The experimental result of the research was realization of bioimpedance signal that used as a reference to control the direction and speed of the wheelchair with a success rate of 86.7 %. A wheelchair velocity was classified into three types of motion, namely slow, medium and fast. Slow speed has a rated speed of 30 Cm/s, medium speed value speed of 40 Cm/s and fast speed value of 50 Cm/s. The wheelchair can also turn to the left and the right in accordance with the wishes of wheelchair user beside to moving forward.

Prediction of fat-free body mass from bioelectrical impedance among 9- to 11-year-old Swedish children

DEFF Research Database (Denmark)

Nielsen, Birgit Marie; Dencker, M; Ward, L

2007-01-01

AIM: Predictive equations for estimating body composition from bioelectrical impedance analysis (BIA) among Scandinavian children are lacking. In the present study, equations for estimation of fat-free body mass (FFM) and lean tissue mass (LTM) were developed and cross-validated from BIA using dual...... linear regression and cross-validated against DXA measurements of body composition. RESULTS: FFM was predicted from BIA and anthropometric variables with an adjusted R(2)= 0.95 and root mean square error (RMSE) = 0.84 kg, and LTM was predicted with an adjusted R(2)= 0.95 and RMSE = 0.87 kg. Cross......-validation revealed a mean RMSE = 0.95 kg FFM and a mean RMSE = 0.96 kg LTM. Prediction of body composition from equations developed in previous literature was mixed when applied to the present cohort of children. CONCLUSIONS: FFM and LTM are predicted with sufficient accuracy at the population level. We recommend...

Biodigestão anaeróbia de efluente de abatedouro avícola

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Arley Borges de Morais Oliveira

2011-12-01

Full Text Available Objetivou-se, com este trabalho, avaliar o processo de biodigestão anaeróbia no tratamento de efluentes de abatedouro avícola, considerando-se os TRH de 7, 14 e 21 dias, além da adição de enzima lipolítica aos substratos, nas concentrações de 0; 0,5; 1,0 e 1,5 g L-1 de carga adicionada aos biodigestores. A influência dos TRH e da adição de enzima lipolítica aos substratos foi avaliada por meio das produções de biogás e CH4, dos potenciais de produção por DQO, adicionada e removida, bem como pelas reduções dos teores de DQO, concentrações de N, P e K e dos valores de pH. Os resultados obtidos demonstraram que houve influência dos TRH (em que o TRH 7 expressou os melhores resultados, para produção semanal média de biogás, com 40,7 L, e CH4, com 32,2 L e das concentrações de enzimas, com maiores valores de produção para os tratamentos 1,0 (24,6 L e 1,5 g L-1 (26,2 L, que não diferiram entre si. As concentrações de enzimas de 1,0 e 1,5 g L-1 apresentaram maiores potenciais de produção de biogás (1,1 e 1,1 L g-1 de DQO adicionada, respectivamente e metano (0,9 e 0,8 L g¹ de DQO adicionada, respectivamente, quando comparadas com as da 0,5 g L-1 (0,8 e 0,7 L g-1 biogás e CH4, respectivamente e 0 (0,7 e 0,5 L g-1 biogás e CH4, respectivamente. As maiores remoções de DQO foram alcançadas nas concentrações de 0,5 g L-1 (83,3% e TRH de 21 dias (74,4%. Contudo, para que haja maior eficiência na reciclagem energética, recomenda-se a utilização de concentrações de 1,0 g L-1 de efluente e tempo de retenção hidráulica de 7 dias.

Ethnic differences in body composition and obesity related risk factors: study in Chinese and white males living in China.

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Dong Wang

Full Text Available The purpose of this cross-sectional observational study was to identify ethnic differences in body composition and obesity-related risk factors between Chinese and white males living in China. 115 Chinese and 114 white male pilots aged 28-63 years were recruited. Fasting body weight, height and blood pressure were measured following standard procedures. Whole-body and segmental body composition were measured using an 8-contact electrode bioimpedance analysis (BIA system. Fasting serum glucose, fasting plasma total cholesterol (TC, high-density lipoprotein (HDL cholesterol, and triglycerides (TG were assessed using automatic biochemistry analyzer. After adjusting for age and body mass index (BMI, Chinese males had significantly higher percentage of body fat (PBF both with respect to whole body (Chinese: 23.7%±0.2% vs. Whites: 22.4%±0.2% and the trunk area (Chinese: 25.0%±0.3% vs. Whites: 23.2%±0.3% compared to their white counterparts. At all BMIs, Chinese males had significantly higher fasting glucose levels (Chinese: 5.7±1.0 mmol/L vs. Whites: 5.2±1.0 mmol/L but lower high-density lipoprotein levels (Chinese: 0.8±1.0 mmol/L vs. Whites: 1.0±1.0 mmol/L than white males. In addition, a marginally significantly higher diastolic blood pressure was found among Chinese men than that among white men (Chinese: 80±1.0 mmHg vs. Whites: 77±1.0 mmHg. Chinese males had more body fat and a greater degree of central fat deposition pattern than that seen in white males in the present study. Furthermore, data on blood pressure, fasting glucose and blood lipids suggest that Chinese men may be more prone to obesity-related risk factors than white men.

Insulin resistance in young adults born small for gestational age (SGA).

Science.gov (United States)

Putzker, Stephanie; Bechtold-Dalla Pozza, Susanne; Kugler, Karl; Schwarz, Hans P; Bonfig, Walter

2014-03-01

This work aimed to assess glucose metabolism and insulin sensitivity in young adults born small for gestational age (SGA) as well as to measure the body composition and adipocytokines of these subjects. A total of 108 out of 342 SGA-born participants were invited for reexamination from the former Bavarian Longitudinal Study (BLS), in which 7505 risk-newborns of the years 1985 to 1986 were prospectively followed. Of these, 76 (34 female/42 male) participants at the age of 19.7±0.5 years were enrolled. Clinical examination and oral glucose tolerance testing (oGTT) was performed with assessment of insulin resistance indices, HbA1c, body mass index (BMI), adipocytokines, and body composition by bioimpedance analysis (BIA). A total of 25 out of 76 (32.9%) patients had abnormal fasting and/or glucose-stimulated insulin levels. Glucose values measured during oGTT showed no abnormalities, except one participant who had impaired glucose tolerance. Homeostasis model assessment insulin resistance index (HOMA-IR) was 1.92±4.2, and insulin sensitivity index by Matsuda (ISI(Matsuda)) showed mean values of 7.85±4.49. HOMA-IR>2.5 was found in 8 patients (10.5%), and 20 patients (26.3%) had an ISI(Matsuda)range for both genders and correlated significantly with BMI (r=0.465, p0.001), but not with adiponectin. Insulin resistance correlated with change in weight-for-height Z-score during the first 3 months of age, indicating that weight gain during that early phase might be a risk factor for the development of insulin resistance in children born SGA. A high percentage of insulin-resistant subjects were reconfirmed in a large German cohort of young adults born SGA. Therefore, regular screening for disturbances in glucose metabolism is recommended in these subjects.

Risks of Breast Implants

Science.gov (United States)

... have a risk of developing a type of cancer called breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) in the breast tissue surrounding the implant. BIA-ALCL is not breast cancer. Women diagnosed with BIA-ALCL may need to ...

Guidelines for conducting pharmaceutical budget impact analyses for submission to public drug plans in Canada.

Science.gov (United States)

Marshall, Deborah A; Douglas, Patrick R; Drummond, Michael F; Torrance, George W; Macleod, Stuart; Manti, Orlando; Cheruvu, Lokanadha; Corvari, Ron

2008-01-01

Until now, there has been no standardized method of performing and presenting budget impact analyses (BIAs) in Canada. Nevertheless, most drug plan managers have been requiring this economic data to inform drug reimbursement decisions. This paper describes the process used to develop the Canadian BIA Guidelines; describes the Guidelines themselves, including the model template; and compares this guidance with other guidance on BIAs. The intended audience includes those who develop, submit or use BIA models, and drug plan managers who evaluate BIA submissions. The Patented Medicine Prices Review Board (PMPRB) initiated the development of the Canadian BIA Guidelines on behalf of the National Prescription Drug Utilisation Information System (NPDUIS). The findings and recommendations from a needs assessment with respect to BIA submissions were reviewed to inform guideline development. In addition, a literature review was performed to identify existing BIA guidance. The detailed guidance was developed on this basis, and with the input of the NPDUIS Advisory Committee, including drug plan managers from multiple provinces in Canada and a representative from the Canadian Agency for Drugs and Technologies in Health. A Microsoft Excel-based interactive model template was designed to support BIA model development. Input regarding the guidelines and model template was sought from each NPDUIS Advisory Committee member to ensure compatibility with existing drug plan needs. Decisions were made by consensus through multiple rounds of review and discussion. Finally, BIA guidance in Canadian provinces and other countries were compared on the basis of multiple criteria. The BIA guidelines consist of three major sections: Analytic Framework, Inputs and Data Sources, and Reporting Format. The Analytic Framework section contains a discussion of nine general issues surrounding BIAs (model design, analytic perspective, time horizon, target population, costing, scenarios to be compared

Assessment of body fat proportion by means of bioelectrical impedance in athletic boys aged 7 to 18 years with respect to specific types of instruments

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Sigmund Martin

2015-07-01

Full Text Available BACKGROUND: Bioelectrical impedance (BIA seems an appropriate method for basic diagnostics of body composition in a practical environment. This is a non-time consuming non-invasive method that provides a high degree of response relevance. However, the values identifi ed by the BIA method are susceptible to a number of factors, which need to be taken into account during the investigation stage and interpretation of the results. One of the signifi cant factors infl uencing the outcomes of measurement is the instrument factor.OBJECTIVE: The objective of the present comparative survey was to analyse the proportions of body fat by means of the BIA hand-to-leg method and BIA leg-to-leg method in a sample of athletic individuals aged 7 to 18 years.METHODS: The survey included a total of 178 ice-hockey players aged 7 to 18 years. The proportion of body fat analysed by means of the BIA hand-to-leg method was measured by the Tanita BC-418 MA instrument. For the purposes of the BIA leg-to-leg method the Tanita BF-350 instrument was used (Tanita, Japan. Both instruments work at a frequency of 50 kHz.RESULTS: The percentage of body fat established by the BIA leg-to-leg method (M = 13.5%; SD = 4.8 indicated signifi cantly lower values of fat percentage than the values measured by the BIA hand-to-leg method (M = 17.1%; SD = 4.3. The overall diff erence represents an average value of 3.6% (standard mode; p < .001; d = 0.8. Regarding the monitored age categories the observed diff erences are in the range of 3.1–4.7% (p < .001; d = 0.7–1.2.CONCLUSION: The present study compares the proportions of body fat by means of the BIA leg-to-leg method and BIA hand-to-leg method in athletic boys aged 7 to 18 years. The results measured by the BIA leg-to-leg method signifi cantly undervalue the proportion of body fat in comparison with the BIA hand-to-leg method. The instrument factor and age factor represented signifi - cant variables infl uencing the results of the

Body composition and hydration factors in infants and young children using multicompartment models

International Nuclear Information System (INIS)

Villegas-Valle, Rosa Consuelo; Valencia, Mauro E; Sotelo-Cruz, Norberto; Antunez-Roman, Lesley Evelyn; Lopez-Jimenez, Cesar A; Monreal-Barraza, Brianda I; Robles-Valenzuela, Edna L; Hurtado-Valenzuela, Jaime Gabriel

2014-01-01

Full text: Background. Until recently deuterium (2H2O) analysis has been performed almost exclusively by isotope ratio mass spectrometry (IRMS). The IAEA has promoted the FTIR methodology to measure deuterium (2H2O) enrichment, but there is limited information in infants and small children, which have different hydration status than adults. Due to the limited information available, the optimum deuterium dose amount to be administered to children in these studies has also been controversial. The aim of this investigation were to measure body composition and determine the hydration factors in infants and young children using multi-compartment models generating algorithms for prediction of body composition. Subjects and Methods. Seventy-eight male and female infants and young children (ages 3-24 months), from the urban and agricultural zones of Hermosillo, Sonora, Mexico participated. We measured weight, length and circumferences to evaluate nutritional status using the WHO Growth Reference 2006. We also measured total body water (TBW) by deuterium oxide dilution, bone mineral content (BMC) through a DXA scan and body density was estimated through published algorithms. Bioimpedance analysis (BIA) was also measured to explore the prediction of body composition using this technique. Results. In general, children from the urban area had better nutritional indicators than children from the agricultural area. Eleven (16.1%) children had some type of malnutrition (any nutritional index below -2 Z cutoff point) and 2 were overweight. Optimal amount of deuterium for dosing in this age range was 0.53 to 0.83 mg/kg body weight, which has implications for future studies of body composition in infants and young children. DXA overestimated body fat percentage compared to other 2, 3 and 4 compartment models (p 0.05). Resistance or impedance indexes (Height2/R or Z) were not important predictors of FFM or TBW (increase in R2 = 0.004). Prediction of FFM was then performed by using

Relação da aptidão aeróbia e muscular com a composição corporal, o estado maturacional e a actividade física habitual de crianças e adolescentes (9-11 anos)

OpenAIRE

João, Félix Rodrigues

2008-01-01

Dissertação de Mestrado em Avaliação nas Actividades Físicas e Desportivas O objectivo deste estudo foi examinar em raparigas e rapazes, com idades compreendidas entre os 9 e os 11 anos de idade, a relação da aptidão aeróbia (ApA) e muscular (ApM) com a composição corporal (MG, massa gorda; MIG, massa isenta de gordura; PCI, perímetro da cintura 1), o índice de actividade física (AFH) e o estado maturacional (EM). Foi também nosso propósito identificar o desempenho dos referidos testes ent...

Flow analysis techniques for phosphorus: an overview.

Science.gov (United States)

Estela, José Manuel; Cerdà, Víctor

2005-04-15

A bibliographical review on the implementation and the results obtained in the use of different flow analytical techniques for the determination of phosphorus is carried out. The sources, occurrence and importance of phosphorus together with several aspects regarding the analysis and terminology used in the determination of this element are briefly described. A classification as well as a brief description of the basis, advantages and disadvantages of the different existing flow techniques, namely; segmented flow analysis (SFA), flow injection analysis (FIA), sequential injection analysis (SIA), all injection analysis (AIA), batch injection analysis (BIA), multicommutated FIA (MCFIA), multisyringe FIA (MSFIA) and multipumped FIA (MPFIA) is also carried out. The most relevant manuscripts regarding the analysis of phosphorus by means of flow techniques are herein classified according to the detection instrumental technique used with the aim to facilitate their study and obtain an overall scope. Finally, the analytical characteristics of numerous flow-methods reported in the literature are provided in the form of a table and their applicability to samples with different matrixes, namely water samples (marine, river, estuarine, waste, industrial, drinking, etc.), soils leachates, plant leaves, toothpaste, detergents, foodstuffs (wine, orange juice, milk), biological samples, sugars, fertilizer, hydroponic solutions, soils extracts and cyanobacterial biofilms are tabulated.

Body Fat Measurements in Singaporean Adults Using Four Methods

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Xinyan Bi

2018-03-01

Full Text Available Few studies have been conducted to measure body composition in Asian populations. In this study, we determined the percent body fat (PBF by using dual-energy X-ray absorptiometry (DEXA, air-displacement plethysmography (ADP or BOD POD, bioelectrical impedance analysis (BIA and skinfold (SKF in 445 healthy Singaporean adults. We observed that the BOD POD, BIA and SKF estimates of PBF were highly correlated with that from DEXA (as a reference method among Singaporean adults. However, they all underestimated PBF (differences of 3.9% for BOD POD, 5.6% for BIA and 12.5% for SKF. Our results filled a gap in the literature by testing the relationships between DEXA and BOD POD, BIA and SKF in a large sample with a wide range of body mass index (BMI from 16.1 to 37.5 kg/m2 and age from 21 to 69.2 years. The differences of PBF measured by different methods were dependent on age, gender and ethnicity. No significant difference was observed between DEXA and BOD POD in men aged > 40 or in BMI tertile 3. However, the mean difference between DEXA and BOD POD was significant in women. Different measuring methods of estimating PBF therefore must be cautiously interpreted.

Deuterium oxide dilution and body composition in overweight and obese schoolchildren aged 6–9 years

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Wendell Costa Bila

2016-01-01

Full Text Available Objective: To correlate different methods of body composition assessment in overweight or obese schoolchildren, using deuterium oxide (D2O dilution as a reference. Methods: Percentage of total body water (%TBW, fat free mass (%FFM, and body fat (%BF were assessed by D2O and tetrapolar electrical bioimpedance analysis (BIA in 54 obese and overweight students aged 6–9 years. Skinfold thickness (ST, body mass index (BMI, conicity index (CI, waist circumference (WC, waist-to-height ratio (WHtR, and waist-to-hip (WHR ratio were also used. Results: Mean values for body composition were 38.4% ± 8.4% BF, 44.9% ± 6.1% TBW and 61.6% ± 8.4% FFM. There was no significant difference in body weight, body fat mass (FM, TBW, and FFM between genders. Regarding D2O, ST underestimated %BF, and overestimated %FFM in both genders (p < 0.05. BIA overestimated %TBW in the group as a whole and in males (p < 0.05. The only positive and strong correlations occurred in females regarding the WC (σ = 0.679, CI (r = 0.634, and WHtR (r = 0.666. Conclusions: In this sample of obese and overweight children, there were strong correlations between body composition measured by D2O and some indices and anthropometric indicators in females, but there was no positive and strong correlation of fat tissue with the indices/indicators at all ages and in both genders. Resumo: Objetivo: Correlacionar diferentes métodos para avaliação de composição corporal em escolares diagnosticados com sobrepeso e obesos, utilizando-se como referência a diluição de óxido de deutério (D2O. Métodos: O percentual de água corporal total (%ACT, massa livre de gordura (%MLG e gordura corporal (%GC foram obtidos pelo D2O e bioimpedância elétrica tetrapolar (BIA, em 54 estudantes com sobrepeso e obesos, com idade entre 6-9 anos. O método das dobras cutâneas (DC utilizando-se triciptal e panturrilha, índice de massa corporal (IMC, índice de conicidade (IC, circunfer

Looking for a road to get out of poverty. Is the current allocation of public spending on education in Colombia helping?

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Blanca Cecilia Zuluaga Díaz

2004-01-01

Full Text Available This paper presents a methodology to explore the impact on poverty of the public spending on education. The methodology consists of two approaches: Benefit Incidence Analysis (BIA and behavioral approach. BIA considers the cost and use of the educational service, and the distribution of the benefits among groups of income. Regarding the behavioral approach, we use a Probit model of schooling attendance, in order to determine the influence of public spending on the probability for the poor to attend the school. As a complement, a measurement of targeting errors in the allocation of public spending is included in the methodology.

BIOIMPEDANCE VECTOR ANALYSIS AS A TOOL FOR DETERMINATION AND ADJUSTMENT OF DRY WEIGHT IN HEMODIALYSIS PATIENTS

OpenAIRE

Ximena Atilano; José Luis.Miguel; Jorge Martínez; Rafael Sánchez; Rafael Selgas

2012-01-01

The hemodialysis (HD) patient is fluid overloaded, even when there is no apparent edema. Due to this, is vital to know the dry weight. No clinical or laboratory parameters are reliable, simple and accessible for this purpose. The bioelectrical impedance has been applied to estimate body fluids and dry weight. The purpose was to use the bioelectrical vector analysis (BIVA) as a tool to adjust the intensity of ultrafiltration and achievement of dry weight in HD patients. We performed monthly me...

Effectiveness of a physical activity program among overweight and obese women

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Öznur Özkan Bambal

2015-04-01

Full Text Available AbstractObjective: This study evaluates the impact of a physical activity (PA intervention program on body composition and anthropometrical measurements among middle aged, overweight and obese women. Methods: This was an interventional study in a semi-urban area. Sample size was calculated as 85 women for each group. The overweight and obese women were assigned to one of two groups by randomization on the basis of a cross-sectional study. Women from both groups participated in a training program on healthy life styles. The intervention group participated in a PA program for three months, three times a week. Anthropometrical and bioelectrical impedance analysis (BIA measurements were performed at the beginning and repeated on 6th and 12th weeks for each group. The Chi square test, Fisher’s exact test, Student’s T test and variance analysis on repeated measures were used for data analysis. Results: Intervention and control groups were similar at the baseline evaluation in terms of their socio-demographic and BIA characteristics. There were statistically significant decreases in both groups in terms of BIA indicators, while body fat percent and trunk fat weight remained unchanged in the control group. When reductions between first and last measurements were compared, for all BIA indicators except for maximum effort capacity scores, muscle weight and body fat percent; the differences were statistically significant in the intervention group. Reductions in body weight, BMI and waist circumference for women who participated in 30 or more PA sessions were higher than for those who participated in 29 or fewer sessions. Conclusions: This PA intervention program was effective for middle aged overweight or obese women in terms of improvement on anthropometrical determinants of obesity. This intervention program can be offered as an appropriate model for similar groups.Key Words: Obesity, intervention study, health promotion, physical activity.

Bureau of Indian Affairs Schools: New Facilities Management Information System Promising, but Improved Data Accuracy Needed.

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General Accounting Office, Washington, DC.

A General Accounting Office (GAO) study evaluated the Bureau of Indian Affairs' (BIA) new facilities management information system (FMIS). Specifically, the study examined whether the new FMIS addresses the old system's weaknesses and meets BIA's management needs, whether BIA has finished validating the accuracy of data transferred from the old…

Study of the dopamine effect into cell solutions by impedance analysis

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Paivana, G.; Apostolou, T.; Kaltsas, G.; Kintzios, S.

2017-11-01

Electrochemical Impedance Spectroscopy (EIS) has become a technique that is frequently used for biological assays. Impedance is defined as a complex - valued generalization of resistance and varies depending on its use per application field. In health sciences, bioimpedance is widely used as non-invasive and low cost alternative in many medical areas that provides valuable information about health status. This work focuses on assessing the effects of a bioactive substance applied to immobilized cells. Dopamine was used as a stimulant in order to implement impedance analysis with a specific type of cells. Dopamine constitutes one of the most important catecholamine neurotransmitters in both the mammalian central and peripheral nervous systems. The main purpose is to extract calibration curves at different frequencies with known dopamine concentrations in order to describe the behavior of cells applied to dopamine using an impedance measurement device. For comparison purposes, non-immobilized cells were tested for the same dopamine concentrations.

Mediterranean Diet and Phase Angle in a Sample of Adult Population: Results of a Pilot Study.

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Barrea, Luigi; Muscogiuri, Giovanna; Macchia, Paolo Emidio; Di Somma, Carolina; Falco, Andrea; Savanelli, Maria Cristina; Colao, Annamaria; Savastano, Silvia

2017-02-17

The Mediterranean diet is a healthy dietary pattern known to actively modulate the cell membrane properties. Phase angle (PhA) is a direct measure by Bioelectrical Impedance Analysis (BIA) used as marker of cell membrane integrity. Both food behaviour and PhA are influenced by age, sex and body weight. The aim of this study was to cross-sectionally evaluate the association between the adherence to Mediterranean diet and PhA in 1013 healthy adult patients stratified according to sex, age, and body mass index (BMI). The adherence to the Mediterranean diet was evaluated using the PREvención con DIeta MEDiterránea (PREDIMED) questionnaire. PhA was calculated by BIA phase-sensitive system (50 kHz BIA 101 RJL, Akern Bioresearch, Florence, Italy Akern). In both sexes, at ROC analysis a PREDIMED score ≥ 6 predicted a PhA beyond the median value. At the multivariate analysis, among PREDIMED score, age, and BMI, the PREDIMED score was the major determinant of PhA, explaining 44.5% and 47.3% of PhA variability, in males and females respectively ( p Mediterranean diet and PhA, independently of sex, age, and body weight. This association uncovered a new potential benefit of the Mediterranean diet on health outcomes, as in both sexes higher adherence to the Mediterranean diet was associated to larger PhAs, as expression of cell membrane integrity.

[Evaluation of nutritional Status in lung cancer using bio electrical impedance analysis and mini nutritional assessment].

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Daghfous, Hafaoua; El Ayeb, Wejdène; Alouane, Leila; Tritar, Fatma

2014-12-01

Malnutrition and cachexia were a frequent problem in lung cancer and increases the risks of morbidity and mortality in these patients. Bioelectrical impedance analysis (BIA) is easy, non-invasive and reproducible method that can be performed. Evaluate nutritional status in patients with primary lung cancer by Mini Nutritional Assessment (MNA), BIA and anthropometric values (weight, arm and calf circumferences) and correlate the nutritional parameters to severity of cancer and histopathology. The nutritional status of 73 cases of primary lung cancer was evaluated by anthropometric parameters, MNA test and impedencemetrie Results: According to body mass index (BMI), malnutrition, overweight and obesity were noted in 34,2%, 13,7% and 5,5%. According to BMI, free-fat mass index (FFMI) and fat mass index (FMI), the investigations occurred malnutrition and depletion of muscle in respectively 19,2% and 23,3% of cases. Fat depletion was noted in 21,9%. Overweight and obesity were detected in 6,8% and 5,5% of cases. Assessment by MNA, revealed that 28,7% of patients were already malnourished and 49,3% of patients were at risk of malnutrition. A significant correlation existed between the score of MNA and arm and calf circumferences, FFMI and FMI. FMI was significantly lower in group of patients with small lung carcinoma. Only FFMI allows early detection of malnutrition in cancer patients overestimated by measuring BMI and arm circumference was the better indicator of depletion of muscle.

Budget impact analysis of drugs for ultra-orphan non-oncological diseases in Europe.

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Schlander, Michael; Adarkwah, Charles Christian; Gandjour, Afschin

2015-02-01

Ultra-orphan diseases (UODs) have been defined by a prevalence of less than 1 per 50,000 persons. However, little is known about budget impact of ultra-orphan drugs. For analysis, the budget impact analysis (BIA) had a time horizon of 10 years (2012-2021) and a pan-European payer's perspective, based on prevalence data for UODs for which patented drugs are available and/or for which drugs are in clinical development. A total of 18 drugs under patent protection or orphan drug designation for non-oncological UODs were identified. Furthermore, 29 ultra-orphan drugs for non-oncological diseases under development that have the potential of reaching the market by 2021 were found. Total budget impact over 10 years was estimated to be €15,660 and €4965 million for approved and pipeline ultra-orphan drugs, respectively (total: €20,625 million). The analysis does not support concerns regarding an uncontrolled growth in expenditures for drugs for UODs.

Phase angle assessment by bioelectrical impedance analysis and its predictive value for malnutrition risk in hospitalized geriatric patients.

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Varan, Hacer Dogan; Bolayir, Basak; Kara, Ozgur; Arik, Gunes; Kizilarslanoglu, Muhammet Cemal; Kilic, Mustafa Kemal; Sumer, Fatih; Kuyumcu, Mehmet Emin; Yesil, Yusuf; Yavuz, Burcu Balam; Halil, Meltem; Cankurtaran, Mustafa

2016-12-01

Phase angle (PhA) value determined by bioelectrical impedance analysis (BIA) is an indicator of cell membrane damage and body cell mass. Recent studies have shown that low PhA value is associated with increased nutritional risk in various group of patients. However, there have been only a few studies performed globally assessing the relationship between nutritional risk and PhA in hospitalized geriatric patients. The aim of the study is to evaluate the predictive value of the PhA for malnutrition risk in hospitalized geriatric patients. One hundred and twenty-two hospitalized geriatric patients were included in this cross-sectional study. Comprehensive geriatric assessment tests and BIA measurements were performed within the first 48 h after admission. Nutritional risk state of the patients was determined with NRS-2002. Phase angle values of the patients with malnutrition risk were compared with the patients that did not have the same risk. The independent variables for predicting malnutrition risk were determined. SPSS version 15 was utilized for the statistical analyzes. The patients with malnutrition risk had significantly lower phase angle values than the patients without malnutrition risk (p = 0.003). ROC curve analysis suggested that the optimum PhA cut-off point for malnutrition risk was 4.7° with 79.6 % sensitivity, 64.6 % specificity, 73.9 % positive predictive value, and 73.9 % negative predictive value. BMI, prealbumin, PhA, and Mini Mental State Examination Test scores were the independent variables for predicting malnutrition risk. PhA can be a useful, independent indicator for predicting malnutrition risk in hospitalized geriatric patients.

Biodigestão anaeróbia de dejetos de bovinos leiteiros submetidos a diferentes tempos de retenção hidráulica

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Amaral Cecília Maria Costa do

2004-01-01

Full Text Available Utilizando-se biodigestores contínuos, abastecidos com dejetos de bovinos leiteiros e operados sob três tempos de retenção hidráulica, avaliou-se o efeito do processo de digestão anaeróbia sobre o número de microrganismos indicadores de poluição fecal, sobre a ocorrência de ovos e larvas de helmintos parasitas de ruminantes, analisando-se também os teores de sólidos totais e voláteis do afluente e dos efluentes, bem como a produção e a qualidade do biogás produzido. Verificou-se que vinte dias de retenção hidráulica foram suficientes para reduzir significativamente o número de microorganismos indicadores de poluição fecal e a quantidade de ovos de helmintos parasitas de ruminantes. Os resultados obtidos nas análises de sólidos totais e voláteis, bem como a produção de biogás (m³/dia, permitem concluir que o biodigestor modelo Chinês operado com 20 dias de tempo de retenção hidráulica, apresentou mais eficiência. Vale ressaltar que vinte dias de retenção foram insuficientes para impedir a sobrevivência de larvas de helmintos parasitas de ruminantes.

Validity of Predictive Equations for Resting Energy Expenditure Developed for Obese Patients: Impact of Body Composition Method

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Achamrah, Najate; Jésus, Pierre; Grigioni, Sébastien; Rimbert, Agnès; Petit, André; Déchelotte, Pierre; Folope, Vanessa; Coëffier, Moïse

2018-01-01

Predictive equations have been specifically developed for obese patients to estimate resting energy expenditure (REE). Body composition (BC) assessment is needed for some of these equations. We assessed the impact of BC methods on the accuracy of specific predictive equations developed in obese patients. REE was measured (mREE) by indirect calorimetry and BC assessed by bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA). mREE, percentages of prediction accuracy (±10% of mREE) were compared. Predictive equations were studied in 2588 obese patients. Mean mREE was 1788 ± 6.3 kcal/24 h. Only the Müller (BIA) and Harris & Benedict (HB) equations provided REE with no difference from mREE. The Huang, Müller, Horie-Waitzberg, and HB formulas provided a higher accurate prediction (>60% of cases). The use of BIA provided better predictions of REE than DXA for the Huang and Müller equations. Inversely, the Horie-Waitzberg and Lazzer formulas provided a higher accuracy using DXA. Accuracy decreased when applied to patients with BMI ≥ 40, except for the Horie-Waitzberg and Lazzer (DXA) formulas. Müller equations based on BIA provided a marked improvement of REE prediction accuracy than equations not based on BC. The interest of BC to improve REE predictive equations accuracy in obese patients should be confirmed. PMID:29320432

Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis

OpenAIRE

M. V. Konovalova; A. V. Anisimova; A. Yu. Vashura; E. Z. Godina; D. V. Nikolaev; S. G. Rudnev; O. A. Starunova; I. A. Khomyakova; G. Ya. Tseytlin

2012-01-01

The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years) and of age-matched healthy controls (n = 1,500) show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell...

Efeitos de 24 semanas de treinamento resistido sobre índices da aptidão aeróbia de mulheres idosas Effects of 24 weeks of resistance training on aerobic fitness indexes of older women

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Marcelo Guido

2010-08-01

Full Text Available INTRODUÇÃO E OBJETIVO: O consumo de oxigênio pico (VO2pico e o limiar anaeróbio (LA são amplamente aceitos como importantes medidas da aptidão aeróbia. Tradicionalmente, o treinamento aeróbio é visto como o principal meio de se aumentar esses índices. Em contrapartida, o treinamento resistido (TR não é tipicamente prescrito para este fim. Em indivíduos idosos, tem sido sugerido que o TR é capaz de aprimorar a capacidade aeróbia; entretanto, a temática é controversa. O objetivo do presente estudo foi verificar os efeitos do treinamento resistido sobre índices da capacidade aeróbia de mulheres idosas. METODOLOGIA: Participaram voluntariamente 50 idosas, as quais foram distribuídas em dois possíveis grupos: grupo controle (GC - n = 25; idade média 68,00 ± 6,38 e grupo treinamento (GT - n = 25; idade média 68,04 ± 6,78 anos. Todas as participantes realizaram teste ergoespirométrico em esteira conduzido até a exaustão voluntária antes e após a intervenção. O GT foi submetido a um programa de TR para os principais grupos musculares três vezes por semana durante um período de 24 semanas. Ao GC foi solicitado que mantivessem suas rotinas habituais. Split plot Anova foi utilizada para verificar possíveis diferenças intra e intergrupos. RESULTADOS: Foi observado que o GT apresentou aumento significativo nas variáveis tempo de teste e VO2, tanto no momento do LA como no momento da exaustão. No GC nenhuma das variáveis dependentes sofreu alteração significativa. CONCLUSÃO: Conclui-se que 24 semanas de TR é capaz de promover melhora no desempenho durante teste de esforço cardiopulmonar em uma amostra de mulheres idosas. Futuros estudos serão importantes para elucidar os mecanismos responsáveis por tais adaptações.INTRODUCTION AND OBJECTIVES: Peak oxygen uptake (VO2 peak and anaerobic threshold (AT have been widely accepted as important predictors of aerobic fitness. Traditionally, aerobic training is viewed as

Endoprótese não cimentada no tratamento de tumor de células gigantes de tíbia, 18 anos de evolução Cementless endoprosthesis in the treatment of giant cell tumor of the tibia, eighteen years of evolution

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Glauco Pauka Mello

2010-01-01

Full Text Available Trata-se de um relato de caso de tumor de células gigantes de tíbia proximal justarticular com fratura patológica. Paciente do sexo feminino, apresentando dor e aumento de volume local após ocorrência de queda da própria altura. Foi submetida ao exame clínico, ao estudo radiográfico e biópsia por punção. Feito diagnóstico de tumor de células gigantes. A paciente foi então tratada com ressecção tumoral e utilização de endoprótese não convencional parcial de tíbia com preservação da superfície articular do platô tibial. A paciente evoluiu com melhora dos sintomas e manutenção da função articular do membro operado, ausência de recidiva e complicações, sem necessidade de reintervenções cirúrgicas em um seguimento de 18 anos.A case report of a giant cell tumor of the proximal tibia justarticular with a pathological fracture. A female patient presenting pain and increase of local volume after a falling incident from an unelevated height. She underwent clinical examination, to radiographic study, and a puncture biopsy. A diagnosis of giant cell tumor was made. The patient was then treated with tumor resection and use of an unconventional partial endoprosthesis of the tibia with preservation of the surface of the tibial plateau. The patient evolved with improvement of symptoms and maintenance of joint function of the operated limb, absence of recurrence and complications, without necessity of reoperation during 18 years of follow-up.

Anaerobic digestion of vinasse: energetic application of biogas and acquisition of credits of carbon – a case Biodigestão anaeróbia da vinhaça: aproveitamento energético do biogás e obtenção de créditos de carbono – estudo de caso

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Rafaelo Balbinot

2010-12-01

Full Text Available The increase of the ethanol production in Brazil leads to growing of vinasse (main by-product of sugar and alcohol industry, worsing the problem related to its destinantion. Vinasse is rich in nutrients and has a high content of organic matter, which justifies its intense ferti-irrigation use in sugar cane crop areas. Thus, the anaerobic digestion of vinasse by UASB (upflow anaerobic sludge blanket digestion reactor emerges as an alternative treatment for this by-product, showing also an economic factor, the production of methane and its use. This work aimed to implement the system of anaerobic digestion of vinasse in UASB reactor and the use of energy generated by biogas. In this way, the design of UASB was based on organic volumetrical load of vinasse. The estimation of the baseline was based on the mass balance between the carbon present in the vinasse and CO2 emitted by the aerobic degradation of effluent into the environment. From the compute emissions, it was found that emissions from the baseline and the project implementation would be the same, and additionally it could be occur the production of electricity by biogas. In this way, biogas produced by anaerobic digestion has a competitive energy potential compared to other energy sources and presents additionality; however, carbon credits marked could not be a financial attractive in the development of this type of project.A crescente produção de etanol no Brasil acarretou aumento na produção de vinhaça (principal subproduto da indústria sucroalcoleira, agravando o problema de sua destinação. A vinhaça é rica em nutrientes minerais e apresenta elevado teor de matéria orgânica, o que justifica sua intensa utilização na fertirrigação de áreas cultivadas com cana. Neste cenário, a biodigestão anaeróbia da vinhaça em reatores UASB (upflow anaerobic sludge blanket digestion surge como uma alternativa de tratamento deste subproduto apresentando, ainda, um fator econ

Estabilidade aeróbia, pH e dinâmica de desenvolvimento de microrganismos da cana-de-açúcar in natura hidrolisada com cal virgem Aerobic stability, pH and development dynamic of microorganisms on fresh sugarcane hydrolyzed with whitewash

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F.N. Domingues

2011-04-01

Full Text Available Objetivou-se com este trabalho avaliar o efeito da adição de cal virgem e dos tempos após a aplicação sobre a estabilidade aeróbia e o crescimento de microrganismos (leveduras e fungos na cana-de-açúcar in natura. O delineamento experimental utilizado foi o inteiramente casualizado, com quatro repetições. Avaliaram-se a estabilidade aeróbia (temperatura, a dinâmica de desenvolvimento de leveduras e fungos e o pH, em um esquema de parcelas subdivididas, com cinco doses de cal (0; 0,5; 1,0; 1,5 e 2,0% e cinco tempos após aplicação (0, 24, 48, 72, 96 horas. Houve efeito significativo das doses de cal para todos os parâmetros avaliados. A cana que não foi tratada com cal (0% apresentou quebra da estabilidade no menor intervalo de tempo. Os valores de pH aumentaram gradativamente de acordo com a dose de cal aplicada e diminuíram com o tempo após aplicação. Houve aumento numérico na contagem de leveduras até as 72 horas após a aplicação da cal, independentemente da dose, e os valores tenderam a estabilizar no tempo de 96 horas pós-tratamento. Não houve efeito significativo das doses de cal sobre o desenvolvimento dos fungos. A aplicação de cal virgem é eficaz no controle do crescimento de leveduras e aumenta a estabilidade aeróbia da cana-de-açúcar in natura.The objective of this work was to evaluate the effect of whitewash addition and the times after application on aerobic stability and growth of microorganisms (fungi and yeasts in fresh sugarcane. It was used a completely randomized experimental design, with four replications. Aerobic stability (temperature and the concentrations of yeast and fungus and pH were evaluated in a split-splot scheme with five doses of whitewash (0; 0.5; 1.0; 1.5 and 2.0% and five times after treatment (0, 24, 48, 72 and 96 hours. There was a significant effect of doses of whitewash for all evaluated parameters. The sugarcane which was not treated with whitewash (0.0% showed a break in

Morphological model of the population of working-age women in Belgrade measured using electrical multichannel bioimpedance model: Pilot study

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Đorđević-Nikić Marina

2013-01-01

Full Text Available The aim of this study was to define the actual model of body composition status of working age women in the territory of Belgrade. The sample comprised 109 women respondents, of an average age of 35.2±9.5 and the length of service = 9.6±9.3 years. All measurements were performed in the period from 2011-2012 in the Teaching -research laboratory of the Faculty of Sport and Physical Education of the University of Belgrade, by applying standardized procedure of electrical multichannel bioimpedance method. The researched encompassed twenty-two (22 variables - fourteen basic (14 and eight (8 derived (index variables. Basic variables were: BH - body height, BM - body mass, ICF - intracellular fluid, ECW - extracellular fluid, TBW - total body fluids, Proteins, Minerals, BMC (Osseous - bone mineral contents, BFM - total body fat mass, SMM - skeletal muscle mass, VFA - visceral fat area, BCM - body cell mass, BMR - basal metabolic rate, FIS - fitness score as assessment of body composition. The derived (index variables were: BMI - body mass index, PBF% - percent of body fat, PBW - percent of body water, PFI - protein fat index, PSMM - percent of skeletal muscle mass, SMMD - skeletal muscle mass density, OBMi - Osseous-body mass index, PBMi - protein body mass index. The results showed that the average body mass of the respondents was 67.66±13.39 kg, body height 167.04±6.62 cm, body mass index 24.27±4.66 kg/m2, muscle mass 26.55±4.46 kg, muscle mass percentage 29.09±8.47, body fat mass 20.52±9.74 kg, body fat percentage 29.09±8.47, visceral fat area was 77.92±40.23 cm2 and fitness score 73.23±6.75 of index points. The obtained results led to the conclusion that the current morphological status of the studied women partially corresponds to a type of normal weight. BMI and the representation of body fat had nearly limiting values towards obesity. A very high percentage of women was recorded in the category of pre-obese and obese according to BMI

Mediterranean Diet and Phase Angle in a Sample of Adult Population: Results of a Pilot Study

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Luigi Barrea

2017-02-01

Full Text Available The Mediterranean diet is a healthy dietary pattern known to actively modulate the cell membrane properties. Phase angle (PhA is a direct measure by Bioelectrical Impedance Analysis (BIA used as marker of cell membrane integrity. Both food behaviour and PhA are influenced by age, sex and body weight. The aim of this study was to cross-sectionally evaluate the association between the adherence to Mediterranean diet and PhA in 1013 healthy adult patients stratified according to sex, age, and body mass index (BMI. The adherence to the Mediterranean diet was evaluated using the PREvención con DIeta MEDiterránea (PREDIMED questionnaire. PhA was calculated by BIA phase-sensitive system (50 kHz BIA 101 RJL, Akern Bioresearch, Florence, Italy Akern. In both sexes, at ROC analysis a PREDIMED score ≥ 6 predicted a PhA beyond the median value. At the multivariate analysis, among PREDIMED score, age, and BMI, the PREDIMED score was the major determinant of PhA, explaining 44.5% and 47.3% of PhA variability, in males and females respectively (p < 0.001. A novel association was reported between the adherence to the Mediterranean diet and PhA, independently of sex, age, and body weight. This association uncovered a new potential benefit of the Mediterranean diet on health outcomes, as in both sexes higher adherence to the Mediterranean diet was associated to larger PhAs, as expression of cell membrane integrity.

Nutrition Status Parameters and Hydration Status by Bioelectrical Impedance Vector Analysis Were Associated With Lung Function Impairment in Children and Adolescents With Cystic Fibrosis.

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Hauschild, Daniela Barbieri; Barbosa, Eliana; Moreira, Emilia Addison Machado; Ludwig Neto, Norberto; Platt, Vanessa Borges; Piacentini Filho, Eduardo; Wazlawik, Elisabeth; Moreno, Yara Maria Franco

2016-06-01

(1) To compare nutrition and hydration status between a group of children/adolescents with cystic fibrosis (CFG; n = 46; median age, 8.5 years) and a control group without cystic fibrosis (CG). (2) To examine the association of nutrition and hydration status with lung function in the CFG. A cross-sectional study. Nutrition screening, anthropometric parameters, and bioelectrical impedance analysis (BIA) were assessed. The z scores for body mass index for age, height for age, mid upper arm circumference, triceps and subscapular skinfold thickness, mid upper arm muscle area, resistance/height, and reactance/height were calculated. Bioelectrical impedance vector analysis was conducted. Forced expiratory volume in 1 second hydration status were associated with lung function. © 2016 American Society for Parenteral and Enteral Nutrition.

Redução de Bactérias Indicadoras de Poluição Fecal em Estrume de Aves de Postura Tratados por Biodigestão Anaeróbia Reduction of Bacterial Indicators of Fecal Pollution in Laying Hens Manure Treated by Anaerobic Digestion

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LA1 Amaral

2000-04-01

Full Text Available A digestão anaeróbia pode auxiliar na redução de patógenos e poluição ambiental pela redução dos sólidos e microrganismos de presença indesejável nos efluentes. No presente trabalho objetivou-se a avaliação da redução de microorganismos indicadores de contaminação fecal através do processo de biodigestão anaeróbica de dejetos de aves de postura em biodigestores contínuos, operados em diferentes tempos de retenção hidráulica (TRH: 40, 30, 25, 20 e 15 dias, e biodigestores de batelada com e sem a utilização de inóculo. Foi observada nos dois tipos de biodigestores uma redução acima de 99,0% para os coliformes totais e fecais, mostrando a eficiência do processo. Os resultados obtidos no presente trabalho mostram que o processo de biodigestão anaeróbia melhora a qualidade microbiológica do estrume, constituindo-se uma medida preventiva importante para se preservar a qualidade do solo e dos mananciais de água, quando da sua aplicação como biofertilizante.The anaerobic digestion can help in the reduction of pathogenic bacteria and to decrease the environmental pollution through the reduction of solids and undesirable microorganisms in the effluents . The present work has as the objective of estimating the reduction of indicators of microorganisms during and after the anaerobic digesting process of litter of hens in continuous bio-digester with different retention time and in non-continuous bio-digester with and without starter A reduction, over 99% of coliforms was observed, showing the efficiency of the process.

Energy Balance of Triathletes during an Ultra-Endurance Event

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Anna Barrero

2014-12-01

Full Text Available The nutritional strategy during an ultra-endurance triathlon (UET is one of the main concerns of athletes competing in such events. The purpose of this study is to provide a proper characterization of the energy and fluid intake during real competition in male triathletes during a complete UET and to estimate the energy expenditure (EE and the fluid balance through the race. Methods: Eleven triathletes performed a UET. All food and drinks ingested during the race were weighed and recorded in order to assess the energy intake (EI during the race. The EE was estimated from heart rate (HR recordings during the race, using the individual HR-oxygen uptake (Vo2 regressions developed from three incremental tests on the 50-m swimming pool, cycle ergometer, and running treadmill. Additionally, body mass (BM, total body water (TBW and intracellular (ICW and extracellular water (ECW were assessed before and after the race using a multifrequency bioimpedance device (BIA. Results: Mean competition time and HR was 755 ± 69 min and 137 ± 6 beats/min, respectively. Mean EI was 3643 ± 1219 kcal and the estimated EE was 11,009 ± 664 kcal. Consequently, athletes showed an energy deficit of 7365 ± 1286 kcal (66.9% ± 11.7%. BM decreased significantly after the race and significant losses of TBW were found. Such losses were more related to a reduction of extracellular fluids than intracellular fluids. Conclusions: Our results confirm the high energy demands of UET races, which are not compensated by nutrient and fluid intake, resulting in a large energy deficit.

Energy balance of triathletes during an ultra-endurance event.

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Barrero, Anna; Erola, Pau; Bescós, Raúl

2014-12-31

The nutritional strategy during an ultra-endurance triathlon (UET) is one of the main concerns of athletes competing in such events. The purpose of this study is to provide a proper characterization of the energy and fluid intake during real competition in male triathletes during a complete UET and to estimate the energy expenditure (EE) and the fluid balance through the race. Eleven triathletes performed a UET. All food and drinks ingested during the race were weighed and recorded in order to assess the energy intake (EI) during the race. The EE was estimated from heart rate (HR) recordings during the race, using the individual HR-oxygen uptake (Vo2) regressions developed from three incremental tests on the 50-m swimming pool, cycle ergometer, and running treadmill. Additionally, body mass (BM), total body water (TBW) and intracellular (ICW) and extracellular water (ECW) were assessed before and after the race using a multifrequency bioimpedance device (BIA). Mean competition time and HR was 755 ± 69 min and 137 ± 6 beats/min, respectively. Mean EI was 3643 ± 1219 kcal and the estimated EE was 11,009 ± 664 kcal. Consequently, athletes showed an energy deficit of 7365 ± 1286 kcal (66.9% ± 11.7%). BM decreased significantly after the race and significant losses of TBW were found. Such losses were more related to a reduction of extracellular fluids than intracellular fluids. Our results confirm the high energy demands of UET races, which are not compensated by nutrient and fluid intake, resulting in a large energy deficit.

DETERMINAÇÃO RÁPIDA E SIMULTÂNEA DE SULFAMETOXAZOL E TRIMETOPRIMA UTILIZANDO ANÁLISE POR INJEÇÃO EM BATELADA COM DETECÇÃO AMPEROMÉTRICA E ELETRODO DE DIAMANTE DOPADO COM BORO

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Polyana Fernandes Pereira

2015-05-01

Full Text Available A fast, simple procedure for simultaneous determination of sulfamethoxazole (SMX and trimethoprim (TMP was performed using batch injection analysis with multiple pulse amperometric detection (BIA-MPA. The sample aliquot (150 µL was directly injected onto the boron-doped diamond (BDD electrode (wall-jet configuration immersed in a BIA system. The analytical characteristics of the proposed method include high analytical frequency (up to 75 injections per hour, good stability (RSD < 2.9%; n = 10, low detection limits (0.227 and 0.173 mg L-1 for SMX and TMP, respectively and minimal waste generation. The proposed method yielded similar results to those obtained by liquid chromatography at a 95% confidence level.

Application of bioelectrical impedance analysis in prediction of light kid carcass and muscle chemical composition.

Science.gov (United States)

Silva, S R; Afonso, J; Monteiro, A; Morais, R; Cabo, A; Batista, A C; Guedes, C M; Teixeira, A

2018-06-01

Carcass data were collected from 24 kids (average live weight of 12.5±5.5 kg; range 4.5 to 22.4 kg) of Jarmelista Portuguese native breed, to evaluate bioelectrical impedance analysis (BIA) as a technique for prediction of light kid carcass and muscle chemical composition. Resistance (Rs, Ω) and reactance (Xc, Ω), were measured in the cold carcasses with a single frequency bioelectrical impedance analyzer and, together with impedance (Z, Ω), two electrical volume measurements (VolA and VolB, cm2/Ω), carcass cold weight (CCW), carcass compactness and several carcass linear measurements were fitted as independent variables to predict carcass composition by stepwise regression analysis. The amount of variation explained by VolA and VolB only reached a significant level (Pcarcass fat weight (0.814⩽R 2⩽0.862; Pcarcass fat weight (combined with carcass length, CL; R 2=0.943; Pcarcass composition.

Who benefits from the Obio Community Health Insurance Scheme in Rivers State, Nigeria? A benefit incidence analysis.

Science.gov (United States)

Vaughan, Kelsey; Akwataghibe, Ngozi; Fakunle, Babatunde; Wolmarans, Liezel

2016-11-01

A key aspect of monitoring and evaluating health programs is ensuring that benefits are reaching their target population. We conducted a benefit incidence analysis (BIA) of a Shell-sponsored community health insurance scheme in Nigeria to determine the extent to which the target group (the poor) was benefitting. We examined a sample of 616 patients' hospital attendance, financial and administrative records from 2012-2013. We estimated annual utilization rates and average unit costs for inpatient and outpatient services. We multiplied the two to produce a total cost per patient, then deducted annual out-of-pocket expenditures to estimate the total community-based health insurance scheme benefit per person. Benefits were multiplied by the total number of persons in each socioeconomic group to aggregate benefits. We used concentration curves and dominance tests to determine statistical significance at 5% and 10% levels of significance. Collectively, the poorest 20% of the population received 12% of benefits while the richest quintile received the largest share (23%). Inpatient and outpatient benefits are weakly regressive (pro-rich), statistically significant at a 10% level of significance. Although the poor were found to benefit, this BIA revealed a tendency towards pro-rich distributions. Removing co-payments for the poorest, reducing long wait and visit times and using community volunteers to help increase access to health services may improve benefits for the poor. © The Author 2016. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Risk factors for type 2 diabetes and cardiovascular disease in Mexican adults from different socio-economic levels

International Nuclear Information System (INIS)

Valencia Juillerat, M.E.; Gallegos, A.C.; Ballesteros, M.N.

2002-01-01

Background: Obesity, type 2 diabetes and cardiovascular disease (CVD) are a major concern in many parts of the world. In Northern Mexico, these problems have been reported to be higher the in the rest of the country. Objective: To assess the different risk factors based on body status (body composition, body size, fat distribution) and lifestyle factors (diet and physical activity) for the development of type 2 diabetes and CVD in men and women from different socio-economic levels in north-west Mexico. Methods: Non probabilistic sample selection by invitation was used to recruit subjects, completing quotas by age groups, gender and socio-economic status. The study included 350 men and women, 20-84 years pertaining to low and high income groups from the city of Hermosillo, Sonora, Mexico. All subjects were measured for body weight, height, waist and hip circumferences, skinfolds, bioimpedance analysis (BIA), systolic and diastolic blood pressure SBP, DBP). Body mass index (BMI) and waist to hip ratio were calculated. An oral glucose tolerance test (OGTT) after a 12 hour fast was performed and blood samples were taken for analysis of insulin, leptin, total cholesterol, HDL, LDL-cholesterol and serum triglycerides. In 273 of the 350 subjects physical activity was studied by questionnaire. Activity was calculated as in categories of low, medium and high intensity and expressed as hours/day with respect to occupational and recreational activities. Physical activity level (PAL) was also calculated from the questionnaires. Body composition was investigated in more detail by air displacement plethysmography (densitometry) and by deuterium dilution in 200 subjects. Diet by 24 hour non-consecutive recalls in another sub-group of 135 male and female subjects. Statistical analysis was performed using NCSS statistical software using ANCOVA and regression procedures. Result: High levels of overweight (BMI >25) and obesity BMI>30) were found in this population group with 65 and

The non-specific symptoms of breast implant-associated anaplastic large cell lymphoma resulting in delayed diagnosis: A case-based review

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Reem Dina Jarjis

2015-12-01

Full Text Available Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL is a rare entity that has become known as a distinct clinical condition recently. In general, BIA-ALCL patients with a history of breast implants present with non-specific implant-related complications, resulting in delayed diagnosis and appropriate treatment because of the lack of awareness of BIA-ALCL. The cause and pathogenesis have still not been identified, and there are no evidence-based guidelines on how this condition should be detected, treated or followed up because of the rarity of available data. We present the first published Danish case of anaplastic lymphoma kinase negative BIA-ALCL, and review the current literature to raise awareness of and discuss management options for this rare clinical entity.

Fermentation, losses, and aerobic stability of sugarcane silages treated with chemical or bacterial additives Fermentação, perdas e estabilidade aeróbia de silagens de cana-de-açúcar tratadas com aditivos químicos ou bacterianos

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André de Faria Pedroso

2008-12-01

Full Text Available Utilization of sugarcane Saccharum officinarum L. silage is increasing in Brazil but intensive ethanol production during fermentation reduces forage quality. This experiment aimed to evaluate the effects of additives on fermentation and aerobic stability of sugarcane silages produced in minisilos. Treatments were (fresh basis: untreated silage (control, urea (5.0 g kg-1, sodium benzoate (1.0 g kg-1, potassium sorbate (0.3 g kg-1, Lactobacillus plantarum (1 x 10(6 cfu g-1, and Lactobacillus buchneri (3.64 x 10(5 cfu g-1. At the 94th day after ensilage, ethanol concentration was lower in urea, benzoate, sorbate and L. buchneri supplemented silages and higher in L. plantarum inoculated silage, as compared to control. Urea and benzoate treated silages showed the highest and L. plantarum treated silage the lowest in vitro dry matter digestibility. Effluent production was higher in the urea treated silage. Inoculation with L. buchneri reduced 50% ethanol production as compared to control. Urea and L. buchneri reduced yeast count. Aerobic stability was enhanced by L. buchneri and benzoate. Sodium benzoate and L. buchneri were the most promising additives, improving both silage fermentation and aerobic stability; inoculants containing L. plantarum can be deleterious to fermentation and conservation of sugarcane silages.A utilização de silagem de cana-de-açúcar (Saccharum officinarum L. está aumentando no Brasil, mas a intensa produção de etanol durante a fermentação reduz a qualidade da forragem. Este experimento visou avaliar os efeitos de aditivos na fermentação e estabilidade aeróbia de silagens de cana-de-açúcar produzidas em minisilos. Os tratamentos foram (base matéria verde: silagem sem tratamento (controle, uréia (5,0 g kg-1, benzoato de sódio (1,0 g kg-1, sorbato de potássio (0,3 g kg-1, Lactobacillus plantarum (1 x 10(6 ufc g-1 e Lactobacillus buchneri (3,64 x 10(5 ufc g-1. Aos 94 dias após a ensilagem, a concentração de

Differences in Body Build and Physical Fitness of PE Students from the Faculty of Physical Education and Sport in Biała Podlaska in the Years 1989, 2004, and 2014

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Saczuk Jerzy

2016-12-01

Full Text Available Introduction. In the current situation of the demographic decline and simultaneous tough competition on the educational market, the issues of not only teaching levels but also the competences and aptitudes of students themselves are raised more and more often. Therefore, this study sought to analyse differences in the body build and physical fitness of physical education (PE students from the Faculty of Physical Education and Sport in Biała Podlaska in the years 1989, 2004, and 2014. Material and methods. The material included the results of the anthropometric measurements and physical fitness tests of second-year students examined in 1989 (n = 111, 2004 (n = 181, and 2014 (n = 127. Martin and Saller’s technique was employed to measure anthropometric features necessary to establish body build types using the Heath-Carter method. Physical fitness was evaluated with the International Physical Fitness Test. Sample size (n, arithmetic mean (x̅, standard deviation (SD, and the T point scale were applied to assess the collected variables. Differences in the sizes of the analysed features between the groups were estimated with the use of ANOVA and the Newman-Keuls test. Results. The analysis revealed a constant increase in basic somatic features and endomorphy and a decrease in mesomorphy and physical fitness in male subjects. The ectomorphy of students examined in 2014 was at a level similar to that recorded in 1989. The pace of the described changes was different depending on the study period. Conclusions. Secular trends in body build and physical fitness observed in the study may stem from deterioration in the biological potential of youths or may result from lowering physical education entrance exam criteria at the university.

75 FR 38595 - Guidance to States Regarding Driver History Record Information Security, Continuity of Operation...

Science.gov (United States)

2010-07-02

... licensing agencies, NIST Interagency Report (IR) 7621, Small Business Information Security: The Fundamentals... emergency. These plans should include a business impact analysis (BIA) to determine: the interdependence of... associated with restoring critical functions (including a line of succession in cases of staff unavailability...

Glutathione S-transferase (GSTM1, GSTT1) gene polymorphisms, maternal gestational weight gain, bioimpedance factors and their relationship with birth weight: a cross-sectional study in Romanian mothers and their newborns.

Science.gov (United States)

Mărginean, Claudiu; Bănescu, Claudia Violeta; Mărginean, Cristina Oana; Tripon, Florin; Meliţ, Lorena Elena; Iancu, Mihaela

2017-01-01

The aim of this study was to assess the relationship between mother-child GSTM1, GSTT1 gene polymorphisms, maternal weight gain, maternal bioimpedance parameters and newborn's weight, in order to identify the factors that influence birth weight. We performed a cross-sectional study on 405 mothers and their newborns, evaluated in an Obstetrics and Gynecology Tertiary Hospital from Romania. Newborns whose mothers had the null genotype of GSTT1 gene polymorphism were more likely to gain a birth weight of >3 kg, compared to newborns whose mothers had the T1 genotype (odds ratio - OR: 2.14, 95% confidence interval - CI: [1.03; 4.44]). Also, the null genotype of GSTM1 gene polymorphism in both mothers and newborns was associated with a higher birth weight. Gestational weight gain was positively associated with newborn's birth weight (pmother's fat mass (%) and basal metabolism rate were also independent factors for a birth weight of more than 3 kg (p=0.006 and p=0.037). The null genotype of GSTT1 gene polymorphism in mothers and the null genotype of GSTM1 in mothers and newborns had a positive effect on birth weight. Also, increased maternal fat mass and basal metabolism rate were associated with increased birth weight. We conclude that maternal GSTM1÷GSTT1 gene polymorphisms present an impact on birth weight, being involved in the neonatal nutritional status. The clinical relevance of our study is sustained by the importance of identifying the factors that influence birth weight, which can be triggers for childhood obesity.

Southpoint power plant final environmental impact statement

International Nuclear Information System (INIS)

1999-01-01

This document is the Final Environmental Impact Statement (FEIS) for a proposed lease of acreage on the Fort Mojave Indian Reservation in Mohave County, Arizona for development of a natural gas fired 500 megawatt combined cycle power plant. The Bureau of Indian Affairs (BIA) serves as the federal lead agency and the Fort Mojave Indian Tribe (FMIT) and the Western Area Power Administration (WAPA) are cooperating agencies for the EIS process. The purpose of this document is to provide information to the public and to interested public agencies regarding the environmental consequences of the approval of a long-term lease for the construction and operation of the proposed Southpoint power plant. The FEIS, prepared by Hallock/Gross, Inc. under the direction of the BIA and in cooperation with the FMIT and WAPA, addresses the comparative analysis of alternatives and evaluates the environmental consequences of such alternatives on various resources and addresses public comments. A number of technical reports were used in the preparation of the Draft EIS and FEIS and are available for review as Appendices to this document under separate cover that can be reviewed at the BIA offices which are listed

[Bioimpedance vector analysis as a tool for the determination and adjustment of dry weight in patients undergoing hemodialysis].

Science.gov (United States)

Atilano-Carsi, Ximena; Miguel, José Luis; Martínez Ara, Jorge; Sánchez Villanueva, Rafael; González García, Elena; Selgas Gutiérrez, Rafael

2015-05-01

Overhydration in hemodialysis patients is associated with cardiovascular mortality. Adequate removal of liquids and achievement of dry weight is one of the main goals of therapy. So far there are no clinical or laboratory parameters that are reliable, simple and affordable for its determination. The bioelectrical impedance vector analysis (BIVE) is a tool that allows identifying and monitoring hydration status, so the aim of this study was to use BIVE to adjust the intensity of ultrafiltration and achieve dry weight in hemodialysis patients. We studied 26 patients on hemodialysis, which were performed monthly measurements of bioelectrical impedance for four months. Corresponding vectors were plotted to know in an individual way the state of hydration, according to which the dry weight was adjusted when necessary. Dry weight adjustment was performed in 13 patients, 7 of which required increase and 6 decrease of dry weight. The displacement of vectors on the ellipses corresponded to the type of intervention made. Dry weight was reached in 84.6% of patients at the end of the study with a significant decrease in mean arterial blood pressure and an increase in phase angle in the group of decrease of dry weight. Bioelectrical impedance vector analysis is an useful tool for adjusting the dry weight in patients undergoing hemodialysis. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Comparison of body fat in Brazilian adult females by bioelectrical impedance analysis

International Nuclear Information System (INIS)

Altamir, Vaz; Frère, Slaets Annie France; Leonardo, López Ramírez

2012-01-01

Body-fat is essential for human body, provided that its amount is at healthy levels. If in-excess body-fat is deleterious, its lack is otherwise also harmful. Estimated percent body-fat performed with commercially available devices measuring bioimpedance have many advantages, such as easy measurement and low cost. However, these measurements are based on standard models and equations that are not disclosed by manufacturers, and this leads to questioning the validity of these estimates for Brazilian females. The aim of this study was to compare electrical tetrapolar and octapolar impedance results obtained with commercially available equipment: Maltron BF-906 and OMRON 510-W. Data analysis involved descriptive and inferential statistics. Devices used in this study to estimate body fat quantity have not shown any significant differences in results; this is a major issue when selecting equipment based on three factors: study focus, available financial resources, and target population. Results obtained from the two devices have not shown any significant differences, which lead to the conclusion that either device may be reliably used.

Increased abdominal fat levels measured by bioelectrical impedance are associated with histological lesions of nonalcoholic steatohepatitis.

Science.gov (United States)

Margariti, Aikaterini; Kontogianni, Meropi D; Tileli, Nafsika; Georgoulis, Michael; Deutsch, Melanie; Zafeiropoulou, Rodessa; Tiniakos, Dina; Manios, Yannis; Pectasides, Dimitrios; Papatheodoridis, George V

2015-08-01

Abdominal fat is considered to play an important role in nonalcoholic fatty liver disease (NAFLD), although it is not adequately studied because abdominal fat levels cannot be estimated easily. In this study, associations between abdominal obesity, as assessed by abdominal bioelectrical impedance analysis (BIA), and the characteristics of patients with NAFLD were explored. Seventy-four consecutive NAFLD patients who underwent measurement of abdominal fat levels by BIA were included. Levels of abdominal fat 12.5 or less and more than 12.5 were considered to be average and increased, respectively. The mean±SD BMI was 30±4 kg/m and the mean abdominal fat levels were 16±5, whereas 26% of patients had average abdominal fat levels. Patients with average compared with those with increased abdominal fat levels were more frequently women (50 vs. 12%, P=0.001), had lower BMI (27±3 vs. 31±4 kg/m, Pabdominal fat levels (78 vs. 38%, P=0.030) and in patients with BMI 30 or more compared with less than 30 kg/m (87 vs. 48%, P=0.033), but similar in patients with increased or normal waist circumference (67 vs. 56%, P=0.693). Average levels of abdominal fat, as assessed by abdominal BIA, are mainly present in female patients with NAFLD and are associated with a lower degree of insulin resistance. Increased abdominal fat as assessed by BIA and obesity seem to represent strong risk factors for histological steatohepatitis.

Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat

Energy Technology Data Exchange (ETDEWEB)

Gonçalves, Daniela [Laboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra (Portugal); CNC – Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra (Portugal); Alves, Gilberto, E-mail: gilberto@fcsaude.ubi.pt [CNC – Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra (Portugal); CICS-UBI – Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã (Portugal); Fortuna, Ana [Laboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra (Portugal); CNC – Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra (Portugal); Soares-da-Silva, Patrício [Department of Research and Development, BIAL – Portela & Ca S.A., Av. da Siderurgia Nacional, 4745-457 S. Mamede do Coronado (Portugal); MedInUP – Center for Drug Discovery and Innovative Medicines, University Porto, Porto (Portugal); Falcão, Amílcar [Laboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra (Portugal); CNC – Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra (Portugal)

2017-05-15

Opicapone is a novel potent, reversible and purely peripheral catechol-O-methyltransferase inhibitor that has been developed to be used as an adjunct to levodopa/aromatic L-amino acid decarboxylase inhibitor therapy for Parkinson's disease. Thus, this study aimed to compare the plasma pharmacokinetics of opicapone and its active metabolite (BIA 9-1079) after the administration of single and multiple oral doses to rats. Wistar rats (n = 8 per group) were orally treated with single (30, 60 or 90 mg/kg) or multiple (30 mg/kg once-daily for seven consecutive days) oral doses of opicapone. Blood samples were collected up to 24 h post-dosing through a cannula introduced in the tail vein of rats. After quantifying opicapone and BIA 9-1079 in plasma, a non-compartmental pharmacokinetic analysis was performed. Opicapone was quickly absorbed (time to reach the maximum plasma concentration ≤ 2 h) in both dosage regimens and the extent of systemic exposure to opicapone increased approximately in a dose-proportional manner after single-dosing within the studied dose range (30–90 mg/kg). Opicapone and BIA 9-1079 showed a relatively short plasma elimination half-life (1.58–4.50 h) and a small systemic accumulation after multiple-dosing. Hence, no pharmacokinetic concerns are expected when opicapone is administered with a once-daily dosing regimen. - Highlights: • Opicapone is relatively rapid absorbed after oral administration to rats. • Systemic exposure to opicapone increases approximately in a dose-proportional manner. • Opicapone and BIA 9-1079 show a small systemic accumulation after multiple-dosing.

GESSO SINTÉTICO E PINOS TRANSCORTICAIS NA REDUÇÃO DE FRATURA DE TÍBIA EM UMA BEZERRA FIBERGLASS CAST AND TRANSCORTICAL PINS IN TIBIAL FRACTURE REDUCTION IN A CALF

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Edivaldo Aparecido Nunes Martins

2001-02-01

Full Text Available Relata-se um caso de fratura de tíbia em uma bezerra de sete meses de idade, 200kg de peso, apresentando fratura fechada, cominutiva em diáfise. A fixação externa foi preferida como método de imobilização óssea, utilizando-se pinos transcorticais e gesso sintético. Obteve-se eficiente imobilização da fratura, com rápida recuperação do animal, dispendendo-se pouco tempo para o pós-operatório (52 dias. A técnica demonstrou ser de fácil realização e passível de ser executada a campo.A case of tibial fracture in a 7-month-old calf is reported, with closed comminuted diaphysial fracture. It has been given preference to external fixation as means of fracture immobilization, and transcortical pins and fiberglass cast have been used. Effective immobilization of the fracture and fast recovering of the animal as well as less time consuming toward the postoperative have been obtained. This technique has showed feasible to be done in the field.

Prevalence of sarcopenia and sarcopenic obesity in older German men using recognized definitions: high accordance but low overlap!

Science.gov (United States)

Kemmler, W; Teschler, M; Weißenfels, A; Sieber, C; Freiberger, E; von Stengel, S

2017-06-01

The relevance of sarcopenia and sarcopenic Obesity (SO) is rising in our aging societies. Applying recognized definitions to 965 community-dwelling Bavarian men 70 years+ resulted in a prevalence for sarcopenia between 3.7 and 4.9 and between 2.1 and 4.1% for SO. Despite this high consistency, the overlap between the definitions/approaches was sarcopenia and sarcopenic obesity (SO) is rising steadily in the aging societies of most developed nations. However, different definitions, components, and cutoff points hinder the evaluation of the prevalence of sarcopenia and SO. The purpose of this contribution was to determine the prevalence of sarcopenia and SO in a cohort of community-dwelling German men 70+ applying established sarcopenia (European Working Group on Sarcopenia in Older People, Foundation National Institute of Health, International Working Group on Sarcopenia) and obesity definitions. Further, we addressed the overlap between the definitions. Altogether, 965 community-dwelling men 70 years and older living in Northern Bavaria, Germany, were assessed during the screening phase of the Franconian Sarcopenic Obesity project. Segmental multi-frequency bio-impedance analysis (BIA) was applied to determine weight and body composition. Applying the definitions of EWGSOP, IWGS, and FNIH, 4.9, 3.8, and 3.7% of the total cohort were classified as sarcopenic, respectively. When further applying body fat to diagnose obesity, SO prevalence in the total cohort ranged from 4.1% (EWGSOP + body fat >25%) to 2.1% (IWGS + body fat >30%). Despite the apparently high consistency of the approaches with respect to prevalence, the overlap in individual sarcopenia diagnosis between the sarcopenia definitions was rather low (sarcopenia and SO in community-dwelling German men 70 years+ is relatively low (sarcopenia diagnosis varies considerably between the three definitions. Since sarcopenia is now recognized as an independent condition by the International Classification of

Body fat measurement by bioelectrical impedance and air displacement plethysmography: a cross-validation study to design bioelectrical impedance equations in Mexican adults

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Valencia Mauro E

2007-08-01

Full Text Available Abstract Background The study of body composition in specific populations by techniques such as bio-impedance analysis (BIA requires validation based on standard reference methods. The aim of this study was to develop and cross-validate a predictive equation for bioelectrical impedance using air displacement plethysmography (ADP as standard method to measure body composition in Mexican adult men and women. Methods This study included 155 male and female subjects from northern Mexico, 20–50 years of age, from low, middle, and upper income levels. Body composition was measured by ADP. Body weight (BW, kg and height (Ht, cm were obtained by standard anthropometric techniques. Resistance, R (ohms and reactance, Xc (ohms were also measured. A random-split method was used to obtain two samples: one was used to derive the equation by the "all possible regressions" procedure and was cross-validated in the other sample to test predicted versus measured values of fat-free mass (FFM. Results and Discussion The final model was: FFM (kg = 0.7374 * (Ht2 /R + 0.1763 * (BW - 0.1773 * (Age + 0.1198 * (Xc - 2.4658. R2 was 0.97; the square root of the mean square error (SRMSE was 1.99 kg, and the pure error (PE was 2.96. There was no difference between FFM predicted by the new equation (48.57 ± 10.9 kg and that measured by ADP (48.43 ± 11.3 kg. The new equation did not differ from the line of identity, had a high R2 and a low SRMSE, and showed no significant bias (0.87 ± 2.84 kg. Conclusion The new bioelectrical impedance equation based on the two-compartment model (2C was accurate, precise, and free of bias. This equation can be used to assess body composition and nutritional status in populations similar in anthropometric and physical characteristics to this sample.

New Application of Bioelectrical Impedance Analysis by the Back Propagation Artificial Neural Network Mathematically Predictive Model of Tissue Composition in the Lower Limbs of Elderly People

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Tsang-Pai Liu

2012-03-01

Conclusion: In summary, the greater predictive accuracy and precision made the application of BIA with the BP–ANN mathematical model more feasible for the clinical measurement of FM and FFM in the lower limbs of elderly people.

78 FR 34039 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

Science.gov (United States)

2013-06-06

...) Georges Bank winter flounder. Sec. 648.86(l) Zero retention of Atlantic wolffish. Sec. 648.86(o..., fecundity, bioelectrical impedance analysis (BIA), food habits, and genetic research. The yellowtail... (GOM), Georges Bank (GB), Southern New England/Mid-Atlantic (SNE/MA)), or 1,200 fish total from each...

Variabilidad de la composición corporal medida con bioimpedanciometría eléctrica según condiciones de realización: influencia del ayuno y del reposo

OpenAIRE

Cáceres, Diana Isabel; Messagi-Sartor, Monique M.; Rodríguez, Diego; Escalada, Ferran; Gea Guiral, Joaquim; Orozco Levi, Mauricio; Marco Peñas, Ester

2014-01-01

Introducción: La bioimpedanciometría eléctrica (BIA) constituye una de las principales herramientas para evaluar la composición corporal. Aunque se recomienda la realización de la BIA en condiciones de ayuno y 60 minutos de reposo, en la práctica asistencial no siempre es posible garantizar su cumplimiento.Objetivos: Determinar la fiabilidad de los parámetros de composición corporal estimados por BIA bajo diferentes condiciones fisiológicas: ayuno + reposo, ayuno + no-reposo y no-ayuno + no- ...

Budget impact analysis of medicines: updated systematic review and implications.

Science.gov (United States)

Faleiros, Daniel Resende; Álvares, Juliana; Almeida, Alessandra Maciel; de Araújo, Vânia Eloisa; Andrade, Eli Iola Gurgel; Godman, Brian B; Acurcio, Francisco A; Guerra Júnior, Augusto A

2016-01-01

This evaluation determines whether published studies to date meet the key characteristics identified for budget impact analyses (BIA) for medicines, accomplished through a systematic review and assessment against identified key characteristics. Studies from 2001-2015 on 'budget impact analysis' with 'drug' interventions were assessed, selected based on their titles/abstracts and full texts, and their characteristics checked according to key criteria. Out of 1,984 studies, 92 were subsequently identified for review. Of these, 95% were published in Europe and the USA. 2012 saw the largest number of publications (16%) with a decline thereafter. 48% met up to 7 out of the 9 key characteristics. Only 22% stated no conflict of interest. The results indicate low adherence to the key characteristics that should be considered for BIAs and strong conflict of interest. This is an issue since BIAs can be of fundamental importance in managing the entry of new medicines including reimbursement decisions.

Dietary habits after myocardial infarction - results from a cross-sectional study.

OpenAIRE

Wallström, Peter; Mattisson, Iréne; Tydén, Patrik; Berglund, Göran; Janzon, Lars

2005-01-01

Objective. Comparing habitual nutrient intakes in persons with a history of acute myocardial infarction (AMI), and age-matched controls. Design. Cross-sectional study. Subjects. Men and women (525 cases and 1890 matched controls), aged 47-73 years, of the population-based Malmö Diet and Cancer cohort. Methods. Nutrient intakes were assessed by a validated modified diet history method. Body fatness was assessed by bioimpedance analysis. Case ascertainment was provided by n...

Impact of eating and drinking on body composition measurements by bioelectrical impedance.

Science.gov (United States)

Androutsos, O; Gerasimidis, K; Karanikolou, A; Reilly, J J; Edwards, C A

2015-04-01

Bioelectrical impedance analysis would be a more practical tool to measure body composition in clinical settings, dietetic practice and epidemiological studies if patients/subjects did not have to fast before measurements. The present study assessed whether the ingestion of food or drink had any biologically significant effect on bioimpedance measurements and body composition by the foot-to-foot method. Fifty-five healthy adults [30 males and 25 females; mean (SD) age 27.7 (7.1) years; mean (SD)body mass index 24 (3.8) kg m(-2)] were randomly assigned to a 2-day food trial (high-fat meal or high-carbohydrate meal) or a 2-day drink trial (water or high electrolyte drink). Body composition measurements were carried out in the fasting state, immediately after meal consumption and every 30 min for 2 h by the foot-to-foot single frequency bioimpedance technique. Bioimpedance increased significantly after the ingestion of food and fluid, although the changes were small. The electrolyte drink, high-fat and high-carbohydrate meals significantly increased the percentage body fat and fat mass. In all cases, the median percentage changes from baseline were approximately 1% in body fat percentage units. Although there were statistically significant changes in body composition estimates after food or drink consumption, these were small and within the imprecision of the impedance technique, and so are unlikely to be of clinical significance. The present study suggests that impedance measures of body fatness in clinical settings do not require strict adherence to fasting, and this should increase the opportunities for clinical application. © 2014 The British Dietetic Association Ltd.

Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity

DEFF Research Database (Denmark)

Lavrsen, Kirstine; Madsen, Caroline B; Rasch, Morten G

2013-01-01

to Tn-MUC1 was investigated using BiaCore. The availability of Tn-MUC1 on the surface of breast cancer cells was evaluated by immunohistochemistry, confocal microscopy, and flow cytometry, followed by in vitro assessment of antibody-dependent cellular cytotoxicity by mAb 5E5. Biacore analysis...

Association between fatness and coronary heart disease risk factors ...

African Journals Online (AJOL)

Body fat was measured by bioelectrical impedance analysis (BIA), and lipid profile (cholesterol, triglycerides and glucose) by the fasting blood test. Weak correlations were obtained between fatness and the CHD risk factors for both genders. Positive correlations were reported for fatness against all the CHD variables except ...

Estimation of body fat from anthropometry and bioelectrical impedance in Native American children.

Science.gov (United States)

Lohman, T G; Caballero, B; Himes, J H; Davis, C E; Stewart, D; Houtkooper, L; Going, S B; Hunsberger, S; Weber, J L; Reid, R; Stephenson, L

2000-08-01

Obesity, as measured by body mass index, is highly prevalent in Native American children, yet there are no valid equations to estimate total body fatness for this population. This study was designed to develop equations to estimate percentage body fat from anthropometry and bioelectrical impedance as a critical part of Pathways, a multi-site study of primary prevention of obesity in Native American children. Percentage fat was estimated from deuterium oxide dilution in 98 Native American children (Pima/Maricopa, Tohono O'odham and White Mountain Apache tribes) between 8 and 11 y of age. The mean fat content (38.4%+/-8. 1%) was calculated assuming the water content of the fat-free body was 76%. Initial independent variables were height, weight, waist circumference, six skinfolds and whole-body resistance and reactance from bioelectrical impedance (BIA). Using all-possible-subsets regressions with the Mallows C (p) criterion, and with age and sex included in each regression model, waist circumference, calf and biceps skinfolds contributed least to the multiple regression analysis. The combination of weight, two skinfolds (any two out of the four best: triceps, suprailiac, subscapular and abdomen) and bioelectrical impedance variables provided excellent predictability. Equations without BIA variables yielded r2 almost as high as those with BIA variables. The recommended equation predicts percentage fat with a root mean square error=3.2% fat and an adjusted r2=0.840. The combination of anthropometry and BIA variables can be used to estimate total body fat in field studies of Native American children. The derived equation yields considerably higher percentage fat values than other skinfold equations in children.

Correlation between alveolar ventilation and electrical properties of lung parenchyma.

Science.gov (United States)

Roth, Christian J; Ehrl, Andreas; Becher, Tobias; Frerichs, Inéz; Schittny, Johannes C; Weiler, Norbert; Wall, Wolfgang A

2015-06-01

One key problem in modern medical imaging is linking measured data and actual physiological quantities. In this article we derive such a link between the electrical bioimpedance of lung parenchyma, which can be measured by electrical impedance tomography (EIT), and the magnitude of regional ventilation, a key to understanding lung mechanics and developing novel protective ventilation strategies. Two rat-derived three-dimensional alveolar microstructures obtained from synchrotron-based x-ray tomography are each exposed to a constant potential difference for different states of ventilation in a finite element simulation. While the alveolar wall volume remains constant during stretch, the enclosed air volume varies, similar to the lung volume during ventilation. The enclosed air, serving as insulator in the alveolar ensemble, determines the resulting current and accordingly local tissue bioimpedance. From this we can derive a relationship between lung tissue bioimpedance and regional alveolar ventilation. The derived relationship shows a linear dependence between air content and tissue impedance and matches clinical data determined from a ventilated patient at the bedside.

Fratura proximal de tíbia após cirurgia extracapsular para correção de ruptura de ligamento cruzado cranial em cão Tibial fracture caused by complications after an extracapsular suture for the repair of cranial cruciate ligament rupture in a dog

Directory of Open Access Journals (Sweden)

Jaqueline França dos Santos

2013-03-01

Full Text Available Ruptura de ligamento cruzado cranial (RLCCr é a afecção ortopédica mais frequente no joelho de cães e a sutura fabelo-tibial é frequentemente utilizada na sua correção. Essa técnica pode estar associada com complicações incisionais, lesão tardia de menisco, edema associado ao material de sutura e infecção. O objetivo desta nota foi relatar a ocorrência de fratura proximal de tíbia em um cão, causada por complicação em sutura fabelo-tibial para correção de RLCCr. Um canino atendido em outro serviço foi submetido à osteossíntese com placa 2,0mm para correção de complicação em técnica extra-capsular, na qual houve fratura da tíbia na região do orifício criado para confecção da sutura fabelo-tibial. Houve falha dos implantes e a placa foi removida. A fratura foi estabilizada com fixador esquelético externo circular, sendo constatada, após 120 dias, consolidação.Cranial cruciate ligament rupture (CCLR is one of the most common orthopedic diseases in dogs and extracapsular suture with nylon is often used for its correction. This technique may be associated with incisional complications, post-surgical meniscus injury, swelling associated with suture material and infection. The objective of this study is to report a tibial fracture in a dog, caused by complications after an extracapsular suture for the repair of CCLR. An adult dog, which suffered a tibial fracture after an extracapsular fixation for a CCLR, underwent surgery for the fixation of the fracture with a 2.0mm plate, by a referring veterinarian, but the implant failed. The plate was removed and the fracture was stabilized with a circular fixator. Bone consolidation was observed after 120 days.

25 CFR 161.604 - What happens if a permit violation occurs?

Science.gov (United States)

2010-04-01

... initiate an appropriate investigation within 5 business days of that notification. (b) Unless otherwise provided under tribal law, when BIA has reason to believe that a permit violation has occurred, BIA or the authorized tribal representative will provide written notice to the permittee within 5 business days. ...

The Impact of National Cultures on Business & IT Alignment

NARCIS (Netherlands)

Drs. A.J.G. Silvius

2008-01-01

Aligning IT to business needs is still one of the most important concerns for senior management. The message of Business & IT Alignment (BIA) is logical and undisputed, but implementation apparently difficult. As part of a research program on the differences between the theory and practice of BIA

XXXIV Bialowieza Workshop on Geometric Methods in Physics

CERN Document Server

Ali, S; Bieliavsky, Pierre; Odzijewicz, Anatol; Schlichenmaier, Martin; Voronov, Theodore

2016-01-01

This book features a selection of articles based on the XXXIV Białowieża Workshop on Geometric Methods in Physics, 2015. The articles presented are mathematically rigorous, include important physical implications and address the application of geometry in classical and quantum physics. Special attention deserves the session devoted to discussions of Gerard Emch's most important and lasting achievements in mathematical physics. The Białowieża workshops are among the most important meetings in the field and gather participants from mathematics and physics alike. Despite their long tradition, the Workshops remain at the cutting edge of ongoing research. For the past several years, the Białowieża Workshop has been followed by a School on Geometry and Physics, where advanced lectures for graduate students and young researchers are presented. The unique atmosphere of the Workshop and School is enhanced by the venue, framed by the natural beauty of the Białowieża forest in eastern Poland.

25 CFR 170.811 - What happens if lack of funds results in inadequate maintenance?

Science.gov (United States)

2010-04-01

... maintenance? 170.811 Section 170.811 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.811 What happens if lack of funds results in inadequate maintenance? If BIA determines that an IRR transportation facility is not being...

Bureau of Indian Affairs Advisory Committee for Exceptional Children. The Third Annual Report to the Department of the Interior.

Science.gov (United States)

Bureau of Indian Affairs (Dept. of Interior), Washington, DC. Div. of Exceptional Education.

The third annual report (1981-82) of the Bureau of Indian Affairs (BIA) Advisory Committee for Exceptional Children contains summaries of Committee meetings, results of a survey of BIA agency and area special education coordinators regarding Committee activities, recommendations, and five appendices. Results of the survey of coordinators indicate…

5 CFR 3501.105 - Outside employment and activities.

Science.gov (United States)

2010-01-01

..., director, employee, agent, attorney, consultant, contractor, general partner, trustee, teacher, or speaker... the Bureau of Indian Affairs (BIA), may not hold a position on a tribal election board or on a tribal... election board and a tribal school board which oversees BIA schools, an eligible person employed in the...

The novel application of artificial neural network on bioelectrical impedance analysis to assess the body composition in elderly

Science.gov (United States)

2013-01-01

Background This study aims to improve accuracy of Bioelectrical Impedance Analysis (BIA) prediction equations for estimating fat free mass (FFM) of the elderly by using non-linear Back Propagation Artificial Neural Network (BP-ANN) model and to compare the predictive accuracy with the linear regression model by using energy dual X-ray absorptiometry (DXA) as reference method. Methods A total of 88 Taiwanese elderly adults were recruited in this study as subjects. Linear regression equations and BP-ANN prediction equation were developed using impedances and other anthropometrics for predicting the reference FFM measured by DXA (FFMDXA) in 36 male and 26 female Taiwanese elderly adults. The FFM estimated by BIA prediction equations using traditional linear regression model (FFMLR) and BP-ANN model (FFMANN) were compared to the FFMDXA. The measuring results of an additional 26 elderly adults were used to validate than accuracy of the predictive models. Results The results showed the significant predictors were impedance, gender, age, height and weight in developed FFMLR linear model (LR) for predicting FFM (coefficient of determination, r2 = 0.940; standard error of estimate (SEE) = 2.729 kg; root mean square error (RMSE) = 2.571kg, P < 0.001). The above predictors were set as the variables of the input layer by using five neurons in the BP-ANN model (r2 = 0.987 with a SD = 1.192 kg and relatively lower RMSE = 1.183 kg), which had greater (improved) accuracy for estimating FFM when compared with linear model. The results showed a better agreement existed between FFMANN and FFMDXA than that between FFMLR and FFMDXA. Conclusion When compared the performance of developed prediction equations for estimating reference FFMDXA, the linear model has lower r2 with a larger SD in predictive results than that of BP-ANN model, which indicated ANN model is more suitable for estimating FFM. PMID:23388042

Body Composition Evaluation Issue among Young Elite Football Players: DXA Assessment

Directory of Open Access Journals (Sweden)

César Leão

2017-02-01

Full Text Available Accurate assessment of body composition is an important issue among athletes. Different methodologies generate controversial results, leading to a deep uncertainty on individual exercise prescriptions. Thus, this study aims to identify the differences between field methods, such as bioelectrical impedance (BIA and skinfold assessment, with a clinical method, highly accurate, dual-energy X-ray absorptiometry (DXA, among elite young football players. Thirty-eight male football players with a mean (sd age of 16.7 (0.87 years, involved in the Portuguese national competition of U16 (n = 13 and U19 (n = 25, were evaluated and objective measures of body composition, muscle strength and football skills were collected by trained specialists. Body composition was assessed using BIA (Tanita BC-418, Tanita Corp., Tokyo, Japan, in agreement with all the evaluation premises. Additionally, all athletes were evaluated using the clinical method DXA (Hologic Inc., Waltham, MA, USA. Among the U19 athletes, three skinfold sites (SKF were assessed: chest, abdomin and thigh. The Spearman correlation coefficients and the mean difference between methods were calculated. The agreement between both methods was analyzed using Bland-Altman plots. Among the evaluated athletes, lower mean values of body fat % were found using BIA as a method of body composition assessment compared with DXA (12.05 vs. 15.58 for U16; 11.97 vs. 14.16 for U19. Despite the moderate correlation between methods (r = 0.33 to estimate the percentage of total fat, the median of the difference (DXA vs. BIA was relevant in clinical terms, with 2.90% and 1.47% for U16 and U19 athletes, respectively. Stronger correlations were found between the sum of the SKF and DXA fat estimation (r = 0.68. The Bland-Altman plots showed a clear underestimation in the evaluations using the BIA, namely among athletes with better body composition profiles (8%–12% of fat. Using BIA, an underestimation of body fat

25 CFR 103.25 - What kind of borrower is eligible under the Program?

Science.gov (United States)

2010-04-01

... the borrower is: (1) An Indian individual; (2) An Indian-owned business entity organized under Federal, State, or tribal law, with an organizational structure reasonably acceptable to BIA; (3) A tribe; or (4) A business enterprise established and recognized by a tribe. (b) To be eligible for a BIA-guaranteed...

76 FR 80403 - Agency Information Collection Activities; Proposed collection; Comments Request: Alien's Change...

Science.gov (United States)

2011-12-23

... collection; Comments Request: Alien's Change of Address Form: 33/BIA Board of Immigration Appeal; 33/IC... Collection. (2) Title of the Form/Collection: Alien's Change of Address Forms 33/BIA Board of Immigration... send notices of the next administrative action or of any decisions in an alien's case. (5) An estimate...

Organizational Change and Conflict: A Case Study of the Bureau of Indian Affairs.

Science.gov (United States)

Champagne, Duane

1983-01-01

Despite attempts by Congress during the 1970s to reform and reorganize the Bureau of Indian Affairs (BIA), it has maintained substantive control over reservation institutions. A key to understanding BIA resistance to change appears to lie in organizational imperative of area directors to preserve and enhance their control over bureaucratic…

Creatine Supplementation Increases Total Body Water in Soccer Players: a Deuterium Oxide Dilution Study.

Science.gov (United States)

Deminice, R; Rosa, F T; Pfrimer, K; Ferrioli, E; Jordao, A A; Freitas, E

2016-02-01

This study aimed to evaluate changes in total body water (TBW) in soccer athletes using a deuterium oxide dilution method and bioelectrical impedance (BIA) formulas after 7 days of creatine supplementation. In a double-blind controlled manner, 13 healthy (under-20) soccer players were divided randomly in 2 supplementation groups: Placebo (Pla, n=6) and creatine supplementation (CR, n=7). Before and after the supplementation period (0.3 g/kg/d during 7 days), TBW was determined by deuterium oxide dilution and BIA methods. 7 days of creatine supplementation lead to a large increase in TBW (2.3±1.0 L) determined by deuterium oxide dilution, and a small but significant increase in total body weight (1.0±0.4 kg) in Cr group compared to Pla. The Pla group did not experience any significant changes in TBW or body weight. Although 5 of 6 BIA equations were sensitive to determine TBW changes induced by creatine supplementation, the Kushner et al. 16 method presented the best concordance levels when compared to deuterium dilution method. In conclusion, 7-days of creatine supplementation increased TBW determined by deuterium oxide dilution or BIA formulas. BIA can be useful to determine TBW changes promoted by creatine supplementation in soccer athletes, with special concern for formula choice. © Georg Thieme Verlag KG Stuttgart · New York.

A study of percentage body fat in children via dual energy X-ray absorptiometry (DEXA)

International Nuclear Information System (INIS)

Kawano, Shoji; Yagi, Shinichi; Fujino, Mitsuyoshi; Tanaka, Hiroyuki; Morita, Tetsuro; Fukunaga, Masao

1994-01-01

Percentage body fat was measured using dual energy X-ray absorptiometry (DEXA), bioelectrical impedance analysis (BIA) and skin fold calipers on 26 children (nine in obesity group, 12 in healthy group and 5 in steroid treated group). Mean percent body fat did not differ significantly between methods in the whole subjects as well as the healthy group and the steroid treated group. However, the mean percent body fat using skin fold caliper was higher for the obesity group than the other two. The measurements of all cases in the obesity group by DEXA were higher than those of BIA. There were high correlations among the percent body fat obtained by each technique. According to the analysis of mean regional percent fat, the percent fat of legs was the highest in the healthy and steroid treated group, while there was no regional difference in the obesity group. It should be possible to classify each case in the obesity group into upper segment and lower segment obesity by DEXA. (author)

Bioactive leptin is stronger related to parameters of fat mass and distribution than conventionally measured leptin: Findings from a longitudinal study in obese children participating in a lifestyle intervention.

Science.gov (United States)

Niklowitz, Petra; Rothermel, Juliane; Lass, Nina; Barth, Andre; Reinehr, Thomas

2018-05-01

This study analyzed the relationships between bioactive leptin, conventionally measured leptin, and parameters of fat mass and distribution in obese children before and after weight reduction. We determined bioactive leptin (bioLep), conventional measured leptin (conLep), weight, height, body fat based on skinfold measurements and bioimpedance analyses, waist circumference (wc), and pubertal stage in 88 obese children participating in a lifestyle intervention at baseline and one year later. We identified no child with homozygous or heterozygous status for bioinactive leptin mutations. The baseline associations between bioLep and BMI (r = 0.53), BMI-SDS (r = 0.48), body fat (bioimpedance: r = 0.61, skinfold thickness: r = 0.49), wc (r = 0.42), and waist to height ratio (whr) (r = 0.39) were stronger than the associations between conLep and BMI (r = 0.50), BMI-SDS (r = 0.44), body fat (bioimpedance: r = 0.57, skinfold thickness: r = 0.41), wc (r = 0.41), and whr (r = 0.37). The changes of bioLep were stronger related to changes of BMI-SDS (r = 0.54), body fat (bioimpedance r = 0.59, skinfold thickness: r = 0.37), wc (r = 0.22), and whr (r = 0.21) than the associations between changes of conLep and changes of BMI-SDS (r = 0.48), body fat (bioimpedance: r = 0.56, skinfold thickness: r = 0.43), wc (r = 0.20), and whr (r = 0.20). The same findings were observed in multiple linear regression analyses adjusted to multiple confounders. In contrast to changes of conLep (r = 0.22), the changes of bioLep during intervention were not related to weight regain after the end of intervention. BioLep concentrations did not differ between prepubertal girls and boys, but were higher in pubertal girls compared to pubertal boys (p = 0.031). Bioactive leptin was stronger related to fat mass and distribution compared to conventionally measured leptin. Copyright © 2018 Elsevier B.V. All rights

76 FR 64377 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Alien's Change...

Science.gov (United States)

2011-10-18

... Collection; Comments Requested: Alien's Change of Address Forms: 33/BIA Board of Immigration Appeals and 33... approved collection. (2) Title of the Form/Collection: Alien's Change of Address Forms: 33/BIA Board of... determine where to send notices of the next administrative action or of any decisions in an alien's case. (5...

The role of geriatric assessment tests and anthropometric measurements in identifying the risk of falls in elderly nursing home residents

Science.gov (United States)

Yardimci, Bulent; Aran, Sinan N.; Ozkaya, Ismail; Aksoy, Sevki M.; Demir, Tarik; Tezcan, Gulsen; Kaptanoglu, Aysegul Y.

2016-01-01

Objectives: To determine the relation among the risk of falls, geriatric assessment, and anthropometric measurements, including the mini mental state examination, geriatric depression scale, handgrip test, and key pinch test. Methods: This prospective study included 89 residents hospitalized between May 2014 and September 2015 in the geriatric care unit of the Istanbul Balikli Rum Hospital, Istanbul, Turkey. Patients were followed-up for one year, and their falls were recorded. Medical records of the included patients were retrieved and analyzed. Results: A total of 89 patients, comprising 37 men and 52 women with an average age of 75.8 ± 8.2 years were included in the study. The residents’ annual falling averages were 1.0 ± 1.5. The most significant factors were identified to be predicted muscle mass, skeletal muscle index, whole body bioimpedance, dominant arm muscle strength, dominant arm bioimpedance, and free fat mass. Conclusions: The mini mental test, geriatric depression scale and lawton-brody scale combined with the handgrip, 6-meters walking, and bioimpedance tests are favorable for detecting the risk of falls and recurrent falls in vulnerable elderly nursing home residents. PMID:27652361

Monitoring fluid status at the outpatient level: the need for more precision.

LENUS (Irish Health Repository)

McDonald, Ken

2010-07-01

Accurate determination of fluid status in patients with heart failure is a critical aspect of care of this population. Early detection of emerging fluid overload would allow for prompt intervention, potentially aborting clinical deterioration and avoiding hospitalization. While many strategies are available to determine fluid status of patients, all areas are compromised by less-than-optimal sensitivity and specificity. Recent work on the role of bioimpedance as a means of assessing a patient\\'s fluid status indicates that this parameter may have a role in monitoring patients with heart failure. This article reviews present techniques available for assessment of fluid status and focuses on the additional information provided by bioimpedance assessment.

Monitoring fluid status at the outpatient level: the need for more precision.

LENUS (Irish Health Repository)

McDonald, Ken

2012-02-01

Accurate determination of fluid status in patients with heart failure is a critical aspect of care of this population. Early detection of emerging fluid overload would allow for prompt intervention, potentially aborting clinical deterioration and avoiding hospitalization. While many strategies are available to determine fluid status of patients, all areas are compromised by less-than-optimal sensitivity and specificity. Recent work on the role of bioimpedance as a means of assessing a patient\\'s fluid status indicates that this parameter may have a role in monitoring patients with heart failure. This article reviews present techniques available for assessment of fluid status and focuses on the additional information provided by bioimpedance assessment.

Microcystin assimilation and detoxification by Daphnia spp. in two ecosystems of different cyanotoxin concentrations

Directory of Open Access Journals (Sweden)

Adrianna Wojtal-Frankiewicz

2013-02-01

Full Text Available Microcystins (MCs, the main group of cyanotoxins, can induce oxidative stress in the cells of aquatic animals. This study evaluated the sensitivity of daphniids – from two ecosystems characterised by different trophic states and habitat levels of cyanobacteria abundance – to microcystin toxicity by analysing oxidative stress parameters and MC detoxification ability. As a study site, we chose the eutrophic Sulejow reservoir, which has regular annual toxic cyanobacterial blooms, and the mesotrophic lake Białe, where low abundances of cyanobacteria have only recently appeared. We found much higher accumulations of MCs in tissues of Daphnia spp. in lake Białe, despite low toxin concentrations in this ecosystem compared with the Sulejow reservoir. Simultaneously, high levels of lipid peroxidation (LPO and a significant decrease in glutathione (GSH were observed in daphniid cells in lake Białe, while LPO levels were generally lower and GSH concentration more stable in the Sulejow reservoir. Catalase activity, which reflects more efficient oxidative protection, was always significantly higher in the reservoir than in lake Białe. These results demonstrate that generations of daphniids from the Sulejow reservoir had more effective antioxidant systems protecting them against the accumulation of cyanobacterial toxins; thereby, they are less susceptible to toxic effects than the daphniids from lake Białe. However, the presence of conjugate forms of microcystins (MC-GSH and MC-Cys in tissues of the studied animals indicated the ability for MC detoxification by daphniids from the Sulejow reservoir and lake Białe. Nevertheless, the high effectiveness of antioxidant systems in daphniids coexisting with cyanobacteria for a long time in the Sulejow reservoir indicates the importance of a selective pressure exerted by toxic cyanobacterial strains that favours the most resistant daphniid genotypes.

25 CFR 170.802 - How is road maintenance funded?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How is road maintenance funded? 170.802 Section 170.802 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.802 How is road maintenance funded? (a) The U.S. Congress funds a BIA...

25 CFR 170.935 - How does a direct service tribe begin the alternative dispute resolution process?

Science.gov (United States)

2010-04-01

....935 How does a direct service tribe begin the alternative dispute resolution process? (a) To begin the ADR process, a direct service tribe must write to the BIA Regional Director or the Chief of BIA... 25 Indians 1 2010-04-01 2010-04-01 false How does a direct service tribe begin the alternative...

Bureau of Indian Affairs Special Education Opportunities for Exceptional Children. The Second Annual Report to the Department of the Interior.

Science.gov (United States)

Bureau of Indian Affairs (Dept. of Interior), Washington, DC.

The report describes 1980-81 meetings and efforts of the Bureau of Indian Affairs (BIA) Advisory Committee for Exceptional Children. Proceedings of three meetings are summarized in Part I. Part II analyzes the Department of Interior/BIA state plans for fiscal years 1980-3. The section lists comments and recommendations for such aspects as the…

ECOLOGIE ALIMENTAIRE DE Brycinus macrolepidotus (PISCES ...

African Journals Online (AJOL)

AISA

... Brycinus macrolepidotus provenant de la rivière Bia. Diet composition and Index of Relative Importance (IRI) of B. macrolepidotus species from the Bia river. n = nombre de spécimens examinés, lac = stations de Bakro et d'Ayamé. n = number of analyzed specimens; lake = Bakro and Ayamé stations. Poissons. Dytiscidae.

Institute of American Indian Arts. To Amend the Act of August 27, 1935, to Provide for the Administration, Maintenance, and Operation of the Institute of American Indian Arts by the Indian Arts and Crafts Board. Hearing Before the Committee on Interior and Insular Affairs. House of Representatives, Ninety-Sixth Congress, Second Session on H.R. 6850.

Science.gov (United States)

Congress of the U.S., Washington, DC. House Committee on Interior and Insular Affairs.

The Committee on Interior and Insular Affairs met July 1, 1980, to take testimony on Bill H.R. 6850 which proposed specific statutory authorization for the Institute of American Indian Arts (IAIA), transferred administrative control from the Bureau of Indian Affairs (BIA) to the Indian Arts and Crafts Board (IACB), and reserved the BIA educational…

23 CFR 661.23 - How will a bridge project be programmed for funding once eligibility has been determined?

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false How will a bridge project be programmed for funding once... bridge project be programmed for funding once eligibility has been determined? (a) All projects will be... time, the project will be acknowledged as either BIA and Tribally owned, or non-BIA owned and placed in...

Identity Activities

Science.gov (United States)

2016-08-03

in reaction to their environment. They reflect an individual’s internal or external, conscious or subconscious , overt or covert, voluntary or...identity activities under a range of legal authorities, policy constraints, transnational threats, regional concerns and biases , and most likely...Biography. A baseline and descriptive analytic product that supports the development of the behavioral influences analysis ( BIA ) individual behavioral

Geometric Methods in Physics : XXXIII Workshop

CERN Document Server

Bieliavsky, Pierre; Odzijewicz, Anatol; Schlichenmaier, Martin; Voronov, Theodore

2015-01-01

This book presents a selection of papers based on the XXXIII Białowieża Workshop on Geometric Methods in Physics, 2014. The Białowieża Workshops are among the most important meetings in the field and attract researchers from both mathematics and physics. The articles gathered here are mathematically rigorous and have important physical implications, addressing the application of geometry in classical and quantum physics. Despite their long tradition, the workshops remain at the cutting edge of ongoing research. For the last several years, each Białowieża Workshop has been followed by a School on Geometry and Physics, where advanced lectures for graduate students and young researchers are presented; some of the lectures are reproduced here. The unique atmosphere of the workshop and school is enhanced by its venue, framed by the natural beauty of the Białowieża forest in eastern Poland. The volume will be of interest to researchers and graduate students in mathematical physics, theoretical physics and m...

23 CFR 661.57 - How is a list of deficient bridges to be generated?

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false How is a list of deficient bridges to be generated? 661... AND TRAFFIC OPERATIONS INDIAN RESERVATION ROAD BRIDGE PROGRAM § 661.57 How is a list of deficient bridges to be generated? (a) In consultation with the BIA, a list of deficient BIA IRR bridges will be...

Equity in the allocation of public sector financial resources in low- and middle-income countries: a systematic literature review.

Science.gov (United States)

Anselmi, Laura; Lagarde, Mylene; Hanson, Kara

2015-05-01

This review aims to identify, assess and analyse the evidence on equity in the distribution of public health sector expenditure in low- and middle-income countries. Four bibliographic databases and five websites were searched to identify quantitative studies examining equity in the distribution of public health funding in individual countries or groups of countries. Two different types of studies were identified: benefit incidence analysis (BIA) and resource allocation comparison (RAC) studies. Quality appraisal and data synthesis were tailored to each study type to reflect differences in the methods used and in the information provided. We identified 39 studies focusing on African, Asian and Latin American countries. Of these, 31 were BIA studies that described the distribution, typically across socio-economic status, of individual monetary benefit derived from service utilization. The remaining eight were RAC studies that compared the actual expenditure across geographic areas to an ideal need-based distribution. Overall, the quality of the evidence from both types of study was relatively weak. Looking across studies, the evidence confirms that resource allocation formulae can enhance equity in resource allocation across geographic areas and that the poor benefits proportionally more from primary health care than from hospital expenditure. The lack of information on the distribution of benefit from utilization in RAC studies and on the countries' approaches to resource allocation in BIA studies prevents further policy analysis. Additional research that relates the type of resource allocation mechanism to service provision and to the benefit distribution is required for a better understanding of equity-enhancing resource allocation policies. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine © The Author 2014; all rights reserved.

Bioimpedance in Severely Malnourished Children

DEFF Research Database (Denmark)

Girma Nigatu, Tsinuel

Worldwide severe acute malnutrition (SAM) affects millions of children and considerably contributes to under-five mortality, mainly in low-income settings. Among children with SAM, deaths occur largely in those with oedema and during early phase of treatment often aggravated by infection. Treatment...

Estabilidade aeróbia da ração total e de silagens de capim-marandu tratadas com aditivos químicos e bacterianos Aerobic stability of total mixed ration and marandugrass silage using microbial or chemical additive

Directory of Open Access Journals (Sweden)

Thiago Fernandes Bernardes

2007-08-01

Full Text Available Esta pesquisa foi realizada com o objetivo de determinar o efeito da inclusão de aditivo químico e da inoculação de bactérias homo e heterofermentativas sobre a estabilidade aeróbia de silagens de capim-marandu e da ração total. Foram conduzidos três experimentos para avaliação do benzoato de sódio e de dois inoculantes, um contendo Lactobacillus plantarum + Propionibacterium e o segundo Lactobacillus buchneri. Após 60 dias de fermentação, os silos foram abertos e as silagens e a ração total (RT contendo silagens de capim-marandu foram colocadas em caixas de isopor e transferidas para câmara climática, a 25 ± 1ºC, para determinação das variações de temperatura na ração total e na silagem, das recuperações de MS e das alterações no pH da silagem. O delineamento experimental foi o inteiramente casualizado, em esquema de parcelas subdivididas. Houve perdas de MS e elevação dos teores de pH quando as silagens foram colocadas em condições de aerobiose. A temperatura das silagens e da RT teve discreto aumento durante os seis dias de aeração. O uso de bactérias ou de benzoato de sódio não influenciou a estabilidade aeróbia das silagens.This research evaluated the inclusion of chemical additive and the inoculation with homo and heterofermentative bacteria on the aerobic stability of the Marandu grass silages and on the total mixed ration (TMR. It was conducted three experiments to evaluate sodium benzoate and two inoculants: 1. Lactobacillus plantarum + Propionibacterium and; 2. Lactobacillus buchneri. The silos were opened after 60 days of fermentation; the silages and the TMR containing the silages were placed in a polystyrene box, and transferred to a climatic chamber kept at 25 ± 1ºC to determine the temperature changes, dry matter recovery, and pH values. The data were analyzed according to a complete randomized design, in a split plot arrangement. The silages showed DM losses and increasing pH during the

Variables associated with lung congestion as assessed by chest ultrasound in diabetics undergoing hemodialysis

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Paulo Roberto Santos

Full Text Available Abstract Introduction: Ultrasound is an emerging method for assessing lung congestion but is still seldom used. Lung congestion is an important risk of cardiac events and death in end-stage renal disease (ESRD patients on hemodialysis (HD. Objective: We investigated possible variables associated with lung congestion among diabetics with ESRD on HD, using chest ultrasound to detect extracellular lung water. Methods: We studied 73 patients with diabetes as the primary cause of ESRD, undergoing regular HD. Lung congestion was assessed by counting the number of B lines detected by chest ultrasound. Hydration status was assessed by bioimpedance analysis and cardiac function by echocardiography. The collapse index of the inferior vena cava (IVC was measured by ultrasonography. All patients were classified according to NYHA score. Correlations of the number of B lines with continuous variables and comparisons regarding the number of B lines according to categorical variables were performed. Multivariate linear regression was used to test the variables as independent predictors of the number of B lines. Results: None of the variables related to hydration status and cardiac function were associated with the number of B lines. In the multivariate analysis, only the IVC collapse index (b = 45.038; p < 0.001 and NYHA classes (b = 13.995; p = 0.006 were independent predictors of the number of B lines. Conclusion: Clinical evaluation based on NYHA score and measurement of the collapsed IVC index were found to be more reliable than bioimpedance analysis to predict lung congestion.

Reliability of non-lethal assessment methods of body composition and energetic status exemplified by applications to eel (Anguilla anguilla) and carp (Cyprinus carpio)

DEFF Research Database (Denmark)

Klefoth, Thomas; Skov, Christian; Aarestrup, Kim

2013-01-01

tNon-lethal assessments of proximate body composition of fish can help unravelling the physiologicaland condition-dependent mechanisms of individual responses to ecological challenges. Common non-lethal methods designed to index nutrient composition in fish include the relative condition factor (Kn......),bioelectric impedance-based assessments of body composition (BIA), and microwave-based “fat” meters(FM). Previous studies have revealed mixed findings as to the reliability of each of these. We compared theperformance of Kn, BIA and FM at different temperatures to predict energetic status of the whole bodiesof live eel...... approach isthe most suitable method to non-lethally estimate energetic status in both, carp and eel, whereas BIA is oflimited use for energetic measurements in the same species, in contrast to other reports in the literature...

Cardiac output measurement

Directory of Open Access Journals (Sweden)

Andreja Möller Petrun

2014-02-01

Full Text Available In recent years, developments in the measuring of cardiac output and other haemodynamic variables are focused on the so-called minimally invasive methods. The aim of these methods is to simplify the management of high-risk and haemodynamically unstable patients. Due to the need of invasive approach and the possibility of serious complications the use of pulmonary artery catheter has decreased. This article describes the methods for measuring cardiac output, which are based on volume measurement (Fick method, indicator dilution method, pulse wave analysis, Doppler effect, and electrical bioimpedance.

Whole-body adipose tissue and lean muscle volumes and their distribution across gender and age: MR-derived normative values in a normal-weight Swiss population.

Science.gov (United States)

Ulbrich, Erika J; Nanz, Daniel; Leinhard, Olof Dahlqvist; Marcon, Magda; Fischer, Michael A

2018-01-01

To determine age- and gender-dependent whole-body adipose tissue and muscle volumes in healthy Swiss volunteers in Dixon MRI in comparison with anthropometric and bioelectrical impedance (BIA) measurements. Fat-water-separated whole-body 3 Tesla MRI of 80 healthy volunteers (ages 20 to 62 years) with a body mass index (BMI) of 17.5 to 26.2 kg/m 2 (10 men, 10 women per decade). Age and gender-dependent volumes of total adipose tissue (TAT), visceral adipose tissue (VAT), total abdominal subcutaneous adipose tissue (ASAT) and total abdominal adipose tissue (TAAT), and the total lean muscle tissue (TLMT) normalized for body height were determined by semi-automatic segmentation, and correlated with anthropometric and BIA measurements as well as lifestyle parameters. The TAT, ASAT, VAT, and TLMT indexes (TATi, ASATi, VATi, and TLMTi, respectively) (L/m 2  ± standard deviation) for women/men were 6.4 ± 1.8/5.3 ± 1.7, 1.6 ± 0.7/1.2 ± 0.5, 0.4 ± 0.2/0.8 ± 0.5, and 5.6 ± 0.6/7.1 ± 0.7, respectively. The TATi correlated strongly with ASATi (r > 0.93), VATi, BMI and BIA (r > 0.70), and TAATi (r > 0.96), and weak with TLMTi for both genders (r > -0.34). The VAT was the only parameter showing an age dependency (r > 0.32). The BMI and BIA showed strong correlation with all MR-derived adipose tissue volumes. The TAT mass was estimated significantly lower from BIA than from MRI (both genders P muscle volumes might serve as normative values. The estimation of adipose tissue volumes was significantly lower from anthropometric and BIA measurements than from MRI. Magn Reson Med 79:449-458, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Inżynierowany jedwab pajęczy: inteligentny biomateriał przyszłości. Część I

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Anna Florczak

2011-06-01

Full Text Available Unikalne właściwości nici pajęczej, takie jak wytrzymałość, rozciągliwość, energia pękania (wiązkość, biokompatybilność oraz biodegradowalność spowodowały intensywny rozwój technologii biomateriałów opartych na białkach jedwabiu pajęczego. Postęp badań naukowych był hamowany przez długi czas brakiem metod pozyskiwania odpowiedniej ilości materiału. Przełomem technologicznym było opracowanie strategii biologii molekularnej, które doprowadziło do stworzenia warunków do produkcji inżynierowanych pajęczych białek jedwabiu (IPJ. Strategia ta polega na konstruowaniu sztucznych białek jedwabiu, których sekwencje oparte są na motywach konsensusowych białek naturalnych. Ponadto białka inżynierowane genetycznie, można skonstruować tak, aby nadać im „nowe” funkcje. Strategia białek hybrydowych zakłada, iż IPJ są rdzeniem, nośnikiem, nadającym strukturę, do którego można dołączyć (na poziomie DNA sekwencję nadającą funkcję np. rozpoznającą receptory komórkowe, enzymy, wiążącą metale, cukry i inne. Obecnie prowadzone są intensywne badania, które z jednej strony skupiają się na ustaleniu szczegółowej budowy i zrozumieniu procesu tworzenia się jedwabnej nici w naturze, a z drugiej strony próbuje się udoskonalić metody produkcji IPJ. Dzięki zdobytej wiedzy i rozwojowi powyższej technologii inżynierowany jedwab stanie się „inteligentnym” biomateriałem przyszłości, a otrzymywany na skalę przemysłową wywoła rewolucję biotechnologiczną.

Peripheral i.v. analysis (PIVA) of venous waveforms for volume assessment in patients undergoing haemodialysis.

Science.gov (United States)

Hocking, K M; Alvis, B D; Baudenbacher, F; Boyer, R; Brophy, C M; Beer, I; Eagle, S

2017-12-01

The assessment of intravascular volume status remains a challenge for clinicians. Peripheral i.v. analysis (PIVA) is a method for analysing the peripheral venous waveform that has been used to monitor volume status. We present a proof-of-concept study for evaluating the efficacy of PIVA in detecting changes in fluid volume. We enrolled 37 hospitalized patients undergoing haemodialysis (HD) as a controlled model for intravascular volume loss. Respiratory rate (F0) and pulse rate (F1) frequencies were measured. PIVA signal was obtained by fast Fourier analysis of the venous waveform followed by weighing the magnitude of the amplitude of the pulse rate frequency. PIVA was compared with peripheral venous pressure and standard monitoring of vital signs. Regression analysis showed a linear correlation between volume loss and change in the PIVA signal (R2=0.77). Receiver operator curves demonstrated that the PIVA signal showed an area under the curve of 0.89 for detection of 20 ml kg-1 change in volume. There was no correlation between volume loss and peripheral venous pressure, blood pressure or pulse rate. PIVA-derived pulse rate and respiratory rate were consistent with similar numbers derived from the bio-impedance and electrical signals from the electrocardiogram. PIVA is a minimally invasive, novel modality for detecting changes in fluid volume status, respiratory rate and pulse rate in spontaneously breathing patients with peripheral i.v. cannulas. © The Author 2017. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com

A Comparison Between Impedance Measured by a Commercial Analyzer and your Value Adjusted by a Theoretical Model in Body Composition Evaluation

National Research Council Canada - National Science Library

Neves, C

2001-01-01

.... One of the greatest applications for such technique is the study of body composition through bioimpedance, where generally a equipment with tetrapolar array set of electrodes is used to realize...

THE RELATION OF FAT FREE MASS TO LUNG FUNCTION, MUSCLE STRENGTH AND EXERCISE PERFORMANCE IN PATIENTS WITH EMPHYSEMA

OpenAIRE

竹中, 英昭

2000-01-01

The purpose of this study was to investigate changes of body composition in patients with pulmonary emphysema (PE) and their influence on physiological function. Body composition analysis by means of bioelectrical impedance analysis (BIA) was performed in 36 patients with stable PE and 19 age-matched healthy controls. I compared fat free mass (FFM) and body fat (BF), as a percentage of ideal body weight (FFM/IBW, BF/IBW), between patients with PE and healthy controls. FFM/IBW and BF /IBW were...

Safety Profile of Eslicarbazepine Acetate as Add-On Therapy in Adults with Refractory Focal-Onset Seizures: From Clinical Studies to 6 Years of Post-Marketing Experience.

Science.gov (United States)

Gama, Helena; Vieira, Mariana; Costa, Raquel; Graça, Joana; Magalhães, Luís M; Soares-da-Silva, Patrício

2017-12-01

Eslicarbazepine acetate was first approved in the European Union in 2009 as adjunctive therapy in adults with partial-onset seizures with or without secondary generalization. The objective of this study was to review the safety profile of eslicarbazepine acetate analyzing the data from several clinical studies to 6 years of post-marketing surveillance. We used a post-hoc pooled safety analysis of four phase III, double-blind, randomized, placebo-controlled studies (BIA-2093-301, -302, -303, -304) of eslicarbazepine acetate as add-on therapy in adults. Safety data of eslicarbazepine acetate in special populations of patients aged ≥65 years with partial-onset seizures (BIA-2093-401) and subjects with moderate hepatic impairment (BIA-2093-111) and renal impairment (BIA-2093-112) are also considered. The incidences of treatment-emergent adverse events, treatment-emergent adverse events leading to discontinuation, and serious adverse events were analyzed. The global safety database of eslicarbazepine acetate was analyzed for all cases from post-marketing surveillance from 1 October, 2009 to 21 October, 2015. From a pooled analysis of four phase III studies, it was concluded that the incidence of treatment-emergent adverse events, treatment-emergent adverse events leading to discontinuation, and adverse drug reactions were dose dependent. Dizziness, somnolence, headache, and nausea were the most common treatment-emergent adverse events (≥10% of patients) and the majority were of mild-to-moderate intensity. No dose-dependent trend was observed for serious adverse events and individual serious adverse events were reported in less than 1% of patients. Hyponatremia was classified as a possibly related treatment-emergent adverse event in phase III studies (1.2%); however, after 6 years of post-marketing surveillance it represents the most frequently (10.2%) reported adverse drug reaction, with more than half of these cases occurring with eslicarbazepine acetate at