42 CFR 412.84 - Payment for extraordinarily high-cost cases (cost outliers).

Science.gov (United States)

2010-10-01

... obtains accurate data with which to calculate either an operating or capital cost-to-charge ratio (or both... outlier payments will be based on operating and capital cost-to-charge ratios calculated based on a ratio... outliers). 412.84 Section 412.84 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF...

Institutional Oversight of Occupational Health and Safety for Research Programs Involving Biohazards

OpenAIRE

Dyson, Melissa C; Carpenter, Calvin B; Colby, Lesley A

2017-01-01

Research with hazardous biologic materials (biohazards) is essential to the progress of medicine and science. The field of microbiology has rapidly advanced over the years, partially due to the development of new scientific methods such as recombinant DNA technology, synthetic biology, viral vectors, and the use of genetically modified animals. This research poses a potential risk to personnel as well as the public and the environment. Institutions must have appropriate oversight and take app...

42 CFR 412.220 - Special treatment of certain hospitals located in Puerto Rico.

Science.gov (United States)

2010-10-01

... Puerto Rico. 412.220 Section 412.220 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... SERVICES Prospective Payment System for Inpatient Operating Costs for Hospitals Located in Puerto Rico § 412.220 Special treatment of certain hospitals located in Puerto Rico. Subpart G of this part sets...

42 CFR 412.90 - General rules.

Science.gov (United States)

2010-10-01

... PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Special Treatment of Certain Facilities Under the Prospective Payment System for Inpatient Operating Costs § 412.90 General rules. (a) Sole community hospitals... after October 1, 1984 are ESRD beneficiary discharges. In determining ESRD discharges, discharges in DRG...

42 CFR 412.212 - National rate.

Science.gov (United States)

2010-10-01

... PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Inpatient Operating... discharge classified within a DRG, the national rate equals the product of— (1) The national average... under § 412.60(b)) for that DRG. (d) Adjusting for different area wage levels. CMS adjusts the...

42 CFR 412.204 - Payment to hospitals located in Puerto Rico.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Payment to hospitals located in Puerto Rico. 412... Payment System for Inpatient Operating Costs for Hospitals Located in Puerto Rico § 412.204 Payment to hospitals located in Puerto Rico. (a) FY 1988 through FY 1997. For discharges occurring on or after October...

42 CFR 412.6 - Cost reporting periods subject to the prospective payment systems.

Science.gov (United States)

2010-10-01

... payment systems. 412.6 Section 412.6 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES... prospective payment system for inpatient operating costs, the reasonable costs of services furnished before...

Institutional Oversight of Occupational Health and Safety for Research Programs Involving Biohazards.

Science.gov (United States)

Dyson, Melissa C; Carpenter, Calvin B; Colby, Lesley A

2017-06-01

Research with hazardous biologic materials (biohazards) is essential to the progress of medicine and science. The field of microbiology has rapidly advanced over the years, partially due to the development of new scientific methods such as recombinant DNA technology, synthetic biology, viral vectors, and the use of genetically modified animals. This research poses a potential risk to personnel as well as the public and the environment. Institutions must have appropriate oversight and take appropriate steps to mitigate the risks of working with these biologic hazards. This article will review responsibilities for institutional oversight of occupational health and safety for research involving biologic hazards.

25 CFR 11.412 - Theft.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Theft. 11.412 Section 11.412 Indians BUREAU OF INDIAN... Criminal Offenses § 11.412 Theft. A person who, without permission of the owner, shall take, shoplift... thereto shall be guilty of theft, a misdemeanor. ...

Safety Evaluation Report related to the operation of Beaver Valley Power Station, Unit 2 (Docket No. 50-412)

International Nuclear Information System (INIS)

1985-10-01

This Safety Evaluation Report on the application filed by Duquesne Light Company, as applicant and agent for the owners, for a license to operate the Beaver Valley Power Station Unit 2 (Docket No. 50-412) has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. The facility is located in Shippingport Borough, Beaver County, Pennsylvania, on the south bank of the Ohio River. Subject to the favorable resolution of the items discussed in this report, the staff concludes that the facility can be operated by the applicant without endangering the health and safety of the public

28 CFR 41.2 - Application.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Application. 41.2 Section 41.2 Judicial Administration DEPARTMENT OF JUSTICE IMPLEMENTATION OF EXECUTIVE ORDER 12250, NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS Federal Agency Responsibilities § 41.2 Application. This part...

7 CFR 412.3 - Index.

Science.gov (United States)

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false Index. 412.3 Section 412.3 Agriculture Regulations of... AGRICULTURE PUBLIC INFORMATION-FREEDOM OF INFORMATION § 412.3 Index. 5 U.S.C. 552(a)(2) requires that each agency publish, or otherwise make available, a current index of all materials available for public...

12 CFR 412.5 - Policy.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Policy. 412.5 Section 412.5 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ACCEPTANCE OF PAYMENT FROM A NON-FEDERAL SOURCE FOR TRAVEL EXPENSES § 412.5 Policy. As provided in this part, Eximbank may accept payment from a non-Federal source...

12 CFR 412.3 - General.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false General. 412.3 Section 412.3 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ACCEPTANCE OF PAYMENT FROM A NON-FEDERAL SOURCE FOR TRAVEL EXPENSES § 412.3 General. (a) Applicability. This part applies to acceptance by the Export-Import Bank of...

Safety evaluation report related to the operation of Beaver Valley Power Station, Unit 2 (Docket No. 50-412)

International Nuclear Information System (INIS)

1986-05-01

This report, Supplement No. 1 to the Safety Evaluation Report for the application filed by the Duquesne Light Company et al. (the applicant) for a license to operate the Beaver valley Power Station, Unit 2 (Docket No. 50-412), has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. This supplement reports the status of certain items that had not been resolved at the time the Safety Evaluation Report was published

12 CFR 412.1 - Authority.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Authority. 412.1 Section 412.1 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ACCEPTANCE OF PAYMENT FROM A NON-FEDERAL SOURCE FOR TRAVEL EXPENSES § 412.1 Authority. This part is issued under the authority of 5 U.S.C. 553, 5 U.S.C. 5701-5709 and...

On the fine spectrum of the generalized difference operator B(r,s over the sequence spaces c0 and c

Directory of Open Access Journals (Sweden)

Bilâl Altay

2005-01-01

Full Text Available We determine the fine spectrum of the generalized difference operator B(r,s defined by a band matrix over the sequence spaces c0 and c, and derive a Mercerian theorem. This generalizes our earlier work (2004 for the difference operator Δ, and includes as other special cases the right shift and the Zweier matrices.

49 CFR 195.412 - Inspection of rights-of-way and crossings under navigable waters.

Science.gov (United States)

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Inspection of rights-of-way and crossings under navigable waters. 195.412 Section 195.412 Transportation Other Regulations Relating to Transportation... Inspection of rights-of-way and crossings under navigable waters. (a) Each operator shall, at intervals not...

Safety Evaluation Report related to the operation of Beaver Valley Power Station, Unit 2 (Docket No. 50-412)

International Nuclear Information System (INIS)

1987-05-01

This report, Supplement No. 5 to the Safety Evaluation Report for the application filed by the Duquesne Light Company et al. (the applicant) for a license to operate the Beaver Valley Power Station, Unit 2 (Docket No. 50-412), has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. This supplement reports the status of certain items that had not been resolved when the Safety Evaluation Report and its Supplements 1, 2, 3, and 4 were published

Safety evaluation report related to the operation of Beaver Valley Power Station, Unit 2 (Docket No. 50-412)

International Nuclear Information System (INIS)

1987-03-01

This report, Supplement No. 4 to the Safety Evaluation Report for the application filed by the Duquesne Light Company et al. (the applicant) for a license to operate the Beaver Valley Power Station, Unit 2 (Docket No. 50-412), has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. This supplement reports the status of certain items that had not been resolved when the Safety Evaluation Report and its Supplements 1, 2, and 3 were published

17 CFR 41.2 - Required records.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Required records. 41.2 Section 41.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SECURITY FUTURES PRODUCTS General Provisions § 41.2 Required records. A designated contract market or registered derivatives...

48 CFR 432.412 - Contract clause.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contract clause. 432.412 Section 432.412 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.412 Contract clause. The decision...

Safety evaluation report related to the operation of Beaver Valley Power Station, Unit 2 (Docket No. 50-412)

International Nuclear Information System (INIS)

1987-08-01

This report, Supplement No. 6 to the Safety Evaluation Report for the application filed by the Duquesne Light Company et al. (the licensee) for a license to operate the Beaver Valley Power Station, Unit 2 (Docket No. 50-412), has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. This supplement reports the status of certain items that had not been resolved when the Safety Evaluation Report and its Supplements 1, 2, 3, 4, and 5 were published

12 CFR 412.11 - Payment guidelines.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Payment guidelines. 412.11 Section 412.11 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ACCEPTANCE OF PAYMENT FROM A NON-FEDERAL SOURCE FOR TRAVEL EXPENSES § 412.11 Payment guidelines. (a) Payments from a non-Federal source, other than...

Closure Report for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR) Tonopah Test Range, Nevada, Revision 0

International Nuclear Information System (INIS)

Matthews, Patrick

2016-01-01

This Closure Report (CR) presents information supporting the clean closure of Corrective Action Unit (CAU) 412: Clean Slate I Plutonium Dispersion (TTR), located on the Tonopah Test Range, Nevada. CAU 412 consists of a release of radionuclides to the surrounding soil from a storage-transportation test conducted on May 25, 1963. Corrective action investigation (CAI) activities were performed in April and May 2015, as set forth in the Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR), Tonopah Test Range, Nevada; and in accordance with the Soils Activity Quality Assurance Plan. The purpose of the CAI was to fulfill data needs as defined during the data quality objectives process. The CAU 412 dataset of investigation results was evaluated based on a data quality assessment. This assessment demonstrated the dataset is complete and acceptable for use in fulfilling the data needs identified by the data quality objectives process. This CR provides documentation and justification for the clean closure of CAU 412 under the FFACO without further corrective action. This justification is based on historical knowledge of the site, previous site investigations, implementation of the 1997 interim corrective action, and the results of the CAI. The corrective action of clean closure was confirmed as appropriate for closure of CAU 412 based on achievement of the following closure objectives: Radiological contamination at the site is less than the final action level using the ground troops exposure scenario (i.e., the radiological dose is less than the final action level): Removable alpha contamination is less than the high contamination area criterion: No potential source material is present at the site, and any impacted soil associated with potential source material has been removed so that remaining soil contains contaminants at concentrations less than the final action levels: and There is

Closure Report for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR) Tonopah Test Range, Nevada, Revision 0

Energy Technology Data Exchange (ETDEWEB)

Matthews, Patrick [Navarro, Las Vegas, NV (United States)

2016-08-22

This Closure Report (CR) presents information supporting the clean closure of Corrective Action Unit (CAU) 412: Clean Slate I Plutonium Dispersion (TTR), located on the Tonopah Test Range, Nevada. CAU 412 consists of a release of radionuclides to the surrounding soil from a storage–transportation test conducted on May 25, 1963. Corrective action investigation (CAI) activities were performed in April and May 2015, as set forth in the Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR), Tonopah Test Range, Nevada; and in accordance with the Soils Activity Quality Assurance Plan. The purpose of the CAI was to fulfill data needs as defined during the data quality objectives process. The CAU 412 dataset of investigation results was evaluated based on a data quality assessment. This assessment demonstrated the dataset is complete and acceptable for use in fulfilling the data needs identified by the data quality objectives process. This CR provides documentation and justification for the clean closure of CAU 412 under the FFACO without further corrective action. This justification is based on historical knowledge of the site, previous site investigations, implementation of the 1997 interim corrective action, and the results of the CAI. The corrective action of clean closure was confirmed as appropriate for closure of CAU 412 based on achievement of the following closure objectives: Radiological contamination at the site is less than the final action level using the ground troops exposure scenario (i.e., the radiological dose is less than the final action level): Removable alpha contamination is less than the high contamination area criterion: No potential source material is present at the site, and any impacted soil associated with potential source material has been removed so that remaining soil contains contaminants at concentrations less than the final action levels: and There is

48 CFR 9904.412-40 - Fundamental requirement.

Science.gov (United States)

2010-10-01

... in current and future cost accounting periods. (b) Measurement of pension cost. (1) For defined.... 9904.412-40 Section 9904.412-40 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.412-40 Fundamental requirement. (a) Components of pension...

48 CFR 9904.412-64 - Transition method.

Science.gov (United States)

2010-10-01

... subsection. (c) Accounting for certain prior allocated unfunded accruals. Any portion of unfunded pension....412-64 Section 9904.412-64 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD... ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.412-64 Transition method. To be acceptable, any method of...

40 CFR 98.412 - GHGs to report.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false GHGs to report. 98.412 Section 98.412 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.412 GHGs to report. You must report...

30 CFR 77.412 - Compressed air systems.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Compressed air systems. 77.412 Section 77.412... for Mechanical Equipment § 77.412 Compressed air systems. (a) Compressors and compressed-air receivers... involving the pressure system of compressors, receivers, or compressed-air-powered equipment shall not be...

42 CFR 412.352 - Budget neutrality adjustment.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Budget neutrality adjustment. 412.352 Section 412.352 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 412.352 Budget neutrality adjustment. For FY 1992 through FY 1995, CMS will determine an adjustment to...

45 CFR 164.412 - Law enforcement delay.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Law enforcement delay. 164.412 Section 164.412 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA STANDARDS AND RELATED... § 164.412 Law enforcement delay. If a law enforcement official states to a covered entity or business...

31 CFR 500.412 - Process vs. manufacture.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Process vs. manufacture. 500.412 Section 500.412 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... Interpretations § 500.412 Process vs. manufacture. A commodity subject to § 500.204 remains subject howsoever it...

12 CFR 412.7 - Conditions for acceptance.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Conditions for acceptance. 412.7 Section 412.7 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ACCEPTANCE OF PAYMENT FROM A NON-FEDERAL SOURCE FOR TRAVEL EXPENSES § 412.7 Conditions for acceptance. (a) Eximbank may accept payment for...

Tyrosine and carboxyl protonation changes in the bacteriorhodopsin photocycle. 1. M412 and L550 intermediates

International Nuclear Information System (INIS)

Roepe, P.; Ahl, P.L.; Gupta, S.K.D.; Herzfeld, J.; Rothschild, K.J.

1987-01-01

The role of tyrosines in the bacteriorhodopsin (bR) photocycle has been investigated by using Fourier transform infrared (FTIR) and UV difference spectroscopies. Tyrosine contributions to the BR 570 → M 412 FTIR difference spectra recorded at several temperatures and pH's were identified by isotopically labeling tyrosine residues in bacteriorhodopsin. The frequencies and deuterium/hydrogen exchange sensitivities of these peaks and of peaks in spectra of model compounds in several environments suggest that at least two different tyrosine groups participate in the bR photocycle during the formation of M 412 . One group undergoes a tyrosinate → tyrosine conversion during the BR 570 → K 630 transition. A second tyrosine group deprotonates between L 550 and M 412 . Low-temperature UV difference spectra in the 220-350-nm region of both purple membrane suspensions and rehydrated films support these conclusions. The UV spectra also indicate perturbations(s) of one or more tryptophan group(s). Several carboxyl groups appear to undergo a series of protonation changes between BR 570 and M 412 , as indicated by infrared absorption changes in the 1770-1720-cm -1 region. These results are consistent with the existence of a proton wire in bacteriorhodopsin that involves both tyrosine and carboxyl groups

42 CFR 412.540 - Method of payment for preadmission services under the long-term care hospital prospective payment...

Science.gov (United States)

2010-10-01

... the long-term care hospital prospective payment system. 412.540 Section 412.540 Public Health CENTERS... PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Long-Term Care Hospitals... payment system. The prospective payment system includes payment for inpatient operating costs of...

12 CFR 412.13 - Limitations and penalties.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Limitations and penalties. 412.13 Section 412.13 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ACCEPTANCE OF PAYMENT FROM A NON-FEDERAL SOURCE FOR TRAVEL EXPENSES § 412.13 Limitations and penalties. (a) This part is in addition to and not in...

Safety Evaluation Report related to the operation of Beaver Valley Power Station, Unit 2 (Docket No. 50-412). Supplement No. 2

International Nuclear Information System (INIS)

1986-08-01

This report, Supplement No. 2 to the the Safety Evaluation Report for the application filed by the Duquesne Light Company, et al. (the applicant) for a license to operate the Beaver Valley Power Station Unit 2 (Docket No. 50-412), has been prepared by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission. This supplement reports the status of certain items that had not been resolved at the time the Safety Evaluation Report was published

Simplifying and extending R*-operation

International Nuclear Information System (INIS)

Chetyrkin, K.G.

1987-04-01

We describe how a recursive procedure to subtract all kinds of divergences (including the infrared ones) which can appear in a Euclidean Feynman integral - the R * -operation - can be both simplified and generalized by reformulating it in terms of the standard Bogoluibov-Parasiuk R-operation alone. The new formulation enjoys at least two advantages over the initial one. irst, it is applicable to evaluating ultraviolet divergences for arbitrary two-dimensional models - the problem which lies somewhat beyond the scope of the original version of the R * -operation. Second, with all qualifications about the pattern of external momenta being removed the reformulated R * -operation should be a convenient tool to treat asymptotic behaviour of an Euclidean Green function when some of its external momenta and/or masses tend to infinity. (orig.)

The Swedish Zero Power Reactor R0

Energy Technology Data Exchange (ETDEWEB)

Landergaard, Olof; Cavallin, Kaj; Jonsson, Georg

1961-05-15

The reactor R0 is a critical facility built for heavy water and natural uranium or fuel of low enrichment,, The first criticality was achieved September 25, 1959. During a first period of more than two years the R0 will be operated as a bare reactor in order to simplify interpretation of results. The reactor tank is 3. 2 m high and 2. 25 m in diameter. The fuel suspension system is quite flexible in order to facilitate fuel exchange and lattice variations. The temperature of the water can be varied between about 10 and 90 C by means of a heater and a cooler placed in the external circulating system. The instrumentation of the reactor has to meet the safety requirements not only during operation but also during rearrangements of the core in the shut-down state. Therefore, the shut-down state is always defined by a certain low 'safe' moderator level in the reactor tank. A number of safety rods are normally kept above the moderator ready for action. For manual or automatic control of the reactor power a specially designed piston pump is needed, by which the moderator level is varied. The pump speed is controlled from the reactor power error by means of a Ward-Leonard system. Moderator level measurement is made by means of a water gauge with an accuracy of {+-} 0. 1 mm.

The Swedish Zero Power Reactor R0

International Nuclear Information System (INIS)

Landergaard, Olof; Cavallin, Kaj; Jonsson, Georg

1961-05-01

The reactor R0 is a critical facility built for heavy water and natural uranium or fuel of low enrichment,, The first criticality was achieved September 25, 1959. During a first period of more than two years the R0 will be operated as a bare reactor in order to simplify interpretation of results. The reactor tank is 3. 2 m high and 2. 25 m in diameter. The fuel suspension system is quite flexible in order to facilitate fuel exchange and lattice variations. The temperature of the water can be varied between about 10 and 90 C by means of a heater and a cooler placed in the external circulating system. The instrumentation of the reactor has to meet the safety requirements not only during operation but also during rearrangements of the core in the shut-down state. Therefore, the shut-down state is always defined by a certain low 'safe' moderator level in the reactor tank. A number of safety rods are normally kept above the moderator ready for action. For manual or automatic control of the reactor power a specially designed piston pump is needed, by which the moderator level is varied. The pump speed is controlled from the reactor power error by means of a Ward-Leonard system. Moderator level measurement is made by means of a water gauge with an accuracy of ± 0. 1 mm

A two-hypothesis approach to establishing a life detection/biohazard protocol for planetary samples

Science.gov (United States)

Conley, Catharine; Steele, Andrew

2016-07-01

The COSPAR policy on performing a biohazard assessment on samples brought from Mars to Earth is framed in the context of a concern for false-positive results. However, as noted during the 2012 Workshop for Life Detection in Samples from Mars (ref. Kminek et al., 2014), a more significant concern for planetary samples brought to Earth is false-negative results, because an undetected biohazard could increase risk to the Earth. This is the reason that stringent contamination control must be a high priority for all Category V Restricted Earth Return missions. A useful conceptual framework for addressing these concerns involves two complementary 'null' hypotheses: testing both of them, together, would allow statistical and community confidence to be developed regarding one or the other conclusion. As noted above, false negatives are of primary concern for safety of the Earth, so the 'Earth Safety null hypothesis' -- that must be disproved to assure low risk to the Earth from samples introduced by Category V Restricted Earth Return missions -- is 'There is native life in these samples.' False positives are of primary concern for Astrobiology, so the 'Astrobiology null hypothesis' -- that must be disproved in order to demonstrate the existence of extraterrestrial life is 'There is no life in these samples.' The presence of Earth contamination would render both of these hypotheses more difficult to disprove. Both these hypotheses can be tested following a strict science protocol; analyse, interprete, test the hypotheses and repeat. The science measurements undertaken are then done in an iterative fashion that responds to discovery with both hypotheses testable from interpretation of the scientific data. This is a robust, community involved activity that ensures maximum science return with minimal sample use.

First Observations of {Upsilon}(1S) {r_arrow} {gamma}{pi}{sup +}{pi}{sup {minus}} and {Upsilon}(1S) {r_arrow} {gamma}{pi}{sup 0}{pi}{sup 0}

Energy Technology Data Exchange (ETDEWEB)

Anastassov, A.; Duboscq, J.E.; Gan, K.K.; Hart, T.; Honscheid, K.; Kagan, H.; Kass, R.; Lee, J.; Schwarthoff, H.; Wolf, A.; Zoeller, M.M. [Ohio State University, Columbus, Ohio 43210 (United States); Richichi, S.J.; Severini, H.; Skubic, P.; Undrus, A. [University of Oklahoma, Norman, Oklahoma 73019 (United States); Bishai, M.; Chen, S.; Fast, J.; Hinson, J.W.; Menon, N.; Miller, D.H.; Shibata, E.I.; Shipsey, I.P. [Purdue University, West Lafayette, Indiana 47907 (United States); Glenn, S.; Kwon, Y.; Lyon, A.L.; Roberts, S.; Thorndike, E.H. [University of Rochester, Rochester, New York 14627 (United States); Jessop, C.P.; Lingel, K.; Marsiske, H.; Perl, M.L.; Savinov, V.; Ugolini, D.; Zhou, X. [Stanford Linear Accelerator Center, Stanford University, Stanford, California 94309 (United States); Coan, T.E.; Fadeyev, V.; Korolkov, I.; Maravin, Y.; Narsky, I.; Stroynowski, R.; Ye, J.; Wlodek, T. [Southern Methodist University, Dallas, Texas 75275 (United States); Artuso, M.; Dambasuren, E.; Kopp, S.; Moneti, G.C.; Mountain, R.; Schuh, S.; Skwarnicki, T.; Stone, S.; Titov, A.; Viehhauser, G.; Wang, J.C. [Syracuse University, Syracuse, New York 13244 (United States); Bartelt, J.; Csorna, S.E.; McLean, K.W.; Marka, S.; Xu, Z. [Vanderbilt University, Nashville, Tennessee 37235 (United States); Godang, R.; Kinoshita, K.; Lai, I.C.; Pomianowski, P.; Schrenk, S. [Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 (United States); Bonvicini, G.; Cinabro, D.; Greene, R.; Perera, L.P.; Zhou, G.J. [Wayne State University, Detroit, Michigan 48202 (United States); Chan, S.; Eigen, G.; Lipeles, E.; Miller, J.S.; Schmidtler, M.; Shapiro, A.; Sun, W.M.; Urheim, J.; Weinstein, A.J.; Wuerthwein, F. [California Institute of Technology, Pasadena, California 91125 (United States); Jaffe, D.E.; Masek, G.; Paar, H.P.; Potter, E.M.; Prell, S.; Sharma, V. [University of California, San Diego, La Jolla, California 92093 (United States); and others

1999-01-01

We report on a study of exclusive radiative decays of the {Upsilon}(1S) resonance collected with the CLEOthinspthinspII detector operating at the Cornell Electron Storage Ring. We present the first observation of the radiative decays {Upsilon}(1S){r_arrow}{gamma}{pi}{sup +}{pi}{sup {minus}} and {Upsilon}(1S){r_arrow}{gamma}{pi}{sup 0}{pi}{sup 0} . For the dipion mass regime m{sub {pi}{pi}}{gt}1.0 GeV , we obtain B({Upsilon}(1S){r_arrow}{gamma}{pi}{sup +}{pi}{sup {minus}})=(6.3{plus_minus}1.2{plus_minus} 1.3){times}10{sup {minus}5} and B({Upsilon}(1S){r_arrow}{gamma}{pi}{sup 0}{pi}{sup 0})=(1.7{plus_minus}0.6{plus_minus} 0.3){times}10{sup {minus}5} . {copyright} {ital 1999} {ital The American Physical Society }

The ratio of free to total serum prostate specific antigen in 412 patients with prostate cancer and analysis of bone metastasis

International Nuclear Information System (INIS)

Cai Jinlai; Dong Li; Pan Fangfang; Gao Zheng; Xu Meihua; Shen Wei

2012-01-01

Objective: To analyze the characteristics of the ratio of serum free prostate specific antigen (FPSA) to total prostate specific antigen (TPSA) and bone metastases in patients with prostate cancer (Pca). Methods: 412 patients with prostate cancer were enrolled in this study. The preoperative serum FPSA and TPSA levels in patients were measured and SPECT imaging with 99m Tc-MDP were carried out. The patients were further divided into 2 groups according to whether they were found with bone metastases. Results: The result showed that 25.5% of patients (105/412) were found without any bone metastasis, and 74.5% of them(307/412) were with bone metastasis. Among the 307 cases of Pca patients with bone metastases, total 2907 metastatic lesions were found. 97.5% of the metastasis showed a 'hot zone' sign, 2.5% of them showed a 'cold zone' sign. The serum levels of TPSA, FPSA and F/T in patients with bone metastasis were 97.9±59.4μg/L, 10.2±8.1μg/L, 0.09±0.04, respectively. The serum levels of TPSA, FPSA and F/T in patients without bone metastasis were 24.8±23.0μg/L, 4.4±3.4μg/L, 0.12±0.05, respectively. There was significantly different in TPSA, FPSA and F/T between two groups (P<0.01). The TPSA in patients was positively correlated with bone metastasis (r=-0.487, P<0.05). There was positively correlation between the ratio of F/T and bone metastasis (r=-0.641, P<0.05). Conclusion: The prostate patients with F/T<0.15 were highly suspected to have bone metastasis. The SPECT bone scan was recommended in these patients when necessary. The bone metastasis predication sites were pelvis, vertebrae and ribs, most of the type of bone metastases were ossification. (authors)

40 CFR 412.21 - Special definitions.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Special definitions. 412.21 Section 412.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND... definitions. For the purposes of this subpart: (a) Dry lot means a facility for growing ducks in confinement...

42 CFR 412.266 - Availability of wage data.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Availability of wage data. 412.266 Section 412.266... Review Board Composition and Procedures § 412.266 Availability of wage data. A hospital may obtain the average hourly wage data necessary to prepare its application to the MGCRB from Federal Register documents...

42 CFR 412.515 - LTC-DRG weighting factors.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false LTC-DRG weighting factors. 412.515 Section 412.515 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE...-Term Care Hospitals § 412.515 LTC-DRG weighting factors. For each LTC-DRG, CMS assigns an appropriate...

42 CFR 412.302 - Introduction to capital costs.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Introduction to capital costs. 412.302 Section 412... Inpatient Hospital Capital Costs General Provisions § 412.302 Introduction to capital costs. (a) New capital... revision of the debt instrument. (iii) If short-term financing was used to acquire old capital assets and...

Streamlined approach for environmental restoration (SAFER) plan for corrective action unit 412: clean slate I plutonium dispersion (TTR) tonopah test range, Nevada, revision 0

Energy Technology Data Exchange (ETDEWEB)

Matthews, Patrick K.

2015-04-01

This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 412. CAU 412 is located on the Tonopah Test Range and consists of a single corrective action site (CAS), TA-23-01CS, Pu Contaminated Soil. There is sufficient information and historical documentation from previous investigations and the 1997 interim corrective action to recommend closure of CAU 412 using the SAFER process. Based on existing data, the presumed corrective action for CAU 412 is clean closure. However, additional data will be obtained during a field investigation to document and verify the adequacy of existing information and determine whether the CAU 412 closure objectives have been achieved. This SAFER Plan provides the methodology to gather the necessary information for closing the CAU.The following summarizes the SAFER activities that will support the closure of CAU 412:• Collect environmental samples from designated target populations to confirm or disprove the presence of contaminants of concern (COCs) as necessary to supplement existing information.• If no COCs are present, establish clean closure as the corrective action. • If COCs are present, the extent of contamination will be defined and further corrective actions will be evaluated with the stakeholders (NDEP, USAF).• Confirm the preferred closure option is sufficient to protect human health and the environment.

12 CFR 412.9 - Conflict of interest analysis.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Conflict of interest analysis. 412.9 Section 412.9 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ACCEPTANCE OF PAYMENT FROM A NON-FEDERAL SOURCE FOR TRAVEL EXPENSES § 412.9 Conflict of interest analysis. Eximbank may accept payment from...

Runoff prediction using rainfall data from microwave links: Tabor case study.

Science.gov (United States)

Stransky, David; Fencl, Martin; Bares, Vojtech

2018-05-01

Rainfall spatio-temporal distribution is of great concern for rainfall-runoff modellers. Standard rainfall observations are, however, often scarce and/or expensive to obtain. Thus, rainfall observations from non-traditional sensors such as commercial microwave links (CMLs) represent a promising alternative. In this paper, rainfall observations from a municipal rain gauge (RG) monitoring network were complemented by CMLs and used as an input to a standard urban drainage model operated by the water utility of the Tabor agglomeration (CZ). Two rainfall datasets were used for runoff predictions: (i) the municipal RG network, i.e. the observation layout used by the water utility, and (ii) CMLs adjusted by the municipal RGs. The performance was evaluated in terms of runoff volumes and hydrograph shapes. The use of CMLs did not lead to distinctively better predictions in terms of runoff volumes; however, CMLs outperformed RGs used alone when reproducing a hydrograph's dynamics (peak discharges, Nash-Sutcliffe coefficient and hydrograph's rising limb timing). This finding is promising for number of urban drainage tasks working with dynamics of the flow. Moreover, CML data can be obtained from a telecommunication operator's data cloud at virtually no cost. That makes their use attractive for cities unable to improve their monitoring infrastructure for economic or organizational reasons.

The origin of high magnetic properties in (R,Zr)(Fe,Co)11.0–11.5Ti1.0–0.5Ny (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

International Nuclear Information System (INIS)

Kobayashi, K.; Suzuki, S.; Kuno, T.; Urushibata, K.; Sakuma, N.; Yano, M.; Shoji, T.; Kato, A.; Manabe, A.

2017-01-01

Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co) 11.0–11.5 Ti 1.0–0.5 N y (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn 12 -type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe 0.75 Co 0.25 ), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti 1.0 to −Ti 0.5 , which increased the Fe and Co content, preserved the ThMn 12 structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe 11 Ti 1.0 N 1.5 , and by 7% for the Co-containing, (Nd 0.7 Zr 0.3 ) (Fe 0.75 Co 0.25 ) 11.5 Ti 0.5 N 1.3 alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

Operation characteristic and performance comparison of organic Rankine cycle (ORC) for low-grade waste heat using R245fa, R123 and their mixtures

International Nuclear Information System (INIS)

Feng, Yong-qiang; Hung, Tzu-Chen; He, Ya-Ling; Wang, Qian; Wang, Shuang; Li, Bing-xi; Lin, Jaw-Ren; Zhang, Wenping

2017-01-01

Highlights: • Experimental comparison using R123, R245fa and their mixtures has been investigated. • The basic operation parameters and the detailed operation characteristics of pure and mixture working fluids are addressed. • The mixture owns a relatively higher pump power consumption, 10–50% higher than that of R245fa and 2–47% higher than that of R123. • The highest system generating efficiency of 4.53% is obtained by 0.67R245fa/0.33R123. - Abstract: The operation characteristic and performance comparison of low-grade organic Rankine cycle (ORC) using R245fa, R123 and their mixtures have been investigated. The heat source temperature is set to be 120 °C, while the mass flow rate is controlled by adjusting the pump frequency. The basic operation parameters are first examined, while the detailed operation characteristics of pure and mixture working fluids are addressed. The system overall performance, including thermal efficiency and system generating efficiency, for pure and mixture working fluids are explored. The experimental results show that the mixtures own a relatively higher pump power consumption and enhancing the pump performance is also significant for ORC application. Whether the mixtures exhibit better thermodynamic performance than the pure working fluids depend on the operation parameters and mass fraction of mixtures. 0.67R245fa/0.33R123 owns the highest maximum net electricity output of 1.67 kW, 4.38% higher than that of R245fa and 63.73% higher than that of R123. Compared to the pure working fluids, the mixture working fluids own a better thermodynamic performance and a moderate economic performance.

42 CFR 412.513 - Patient classification system.

Science.gov (United States)

2010-10-01

... LTC-DRG classification system provides a LTC-DRG, and an appropriate weighting factor, for those cases... intermediary decides that a different LTC-DRG should be assigned, the case will be reviewed by the appropriate... 42 Public Health 2 2010-10-01 2010-10-01 false Patient classification system. 412.513 Section 412...

33 CFR 149.412 - How many fire axes are needed?

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false How many fire axes are needed? 149.412 Section 149.412 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... Protection Equipment Firefighting Requirements § 149.412 How many fire axes are needed? Each manned deepwater...

Complete genome sequences of Geobacillus sp. Y412MC52, a xylan-degrading strain isolated from obsidian hot spring in Yellowstone National Park.

Science.gov (United States)

Brumm, Phillip; Land, Miriam L; Hauser, Loren J; Jeffries, Cynthia D; Chang, Yun-Juan; Mead, David A

2015-01-01

Geobacillus sp. Y412MC52 was isolated from Obsidian Hot Spring, Yellowstone National Park, Montana, USA under permit from the National Park Service. The genome was sequenced, assembled, and annotated by the DOE Joint Genome Institute and deposited at the NCBI in December 2011 (CP002835). Based on 16S rRNA genes and average nucleotide identity, Geobacillus sp. Y412MC52 and the related Geobacillus sp. Y412MC61 appear to be members of a new species of Geobacillus. The genome of Geobacillus sp. Y412MC52 consists of one circular chromosome of 3,628,883 bp, an average G + C content of 52 % and one circular plasmid of 45,057 bp and an average G + C content of 45 %. Y412MC52 possesses arabinan, arabinoglucuronoxylan, and aromatic acid degradation clusters for degradation of hemicellulose from biomass. Transport and utilization clusters are also present for other carbohydrates including starch, cellobiose, and α- and β-galactooligosaccharides.

20 CFR 654.412 - Bathing, laundry, and handwashing.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Bathing, laundry, and handwashing. 654.412... RESPONSIBILITIES OF THE EMPLOYMENT SERVICE SYSTEM Housing for Agricultural Workers Housing Standards § 654.412 Bathing, laundry, and handwashing. (a) Bathing and handwashing facilities, supplied with hot and cold...

50 CFR 660.412 - EFH identifications and descriptions for Pacific salmon.

Science.gov (United States)

2010-10-01

... Pacific salmon. 660.412 Section 660.412 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT... COAST STATES West Coast Salmon Fisheries § 660.412 EFH identifications and descriptions for Pacific salmon. Pacific salmon essential fish habitat (EFH) includes all those water bodies occupied or...

42 CFR 412.320 - Disproportionate share adjustment factor.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Disproportionate share adjustment factor. 412.320... Capital-Related Costs § 412.320 Disproportionate share adjustment factor. (a) Criteria for classification... adjustment factor. (1) If a hospital meets the criteria in paragraph (a)(1) of this section for a...

48 CFR 9904.412-50 - Techniques for application.

Science.gov (United States)

2010-10-01

... to a cost accounting period shall be accounted for as a prepayment credit. The accumulated value of... towards pension cost in a future accounting period. The accumulated value of prepayment credits shall be.... 9904.412-50 Section 9904.412-50 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD...

ETV6-NTRK3 as a therapeutic target of small molecule inhibitor PKC412

Energy Technology Data Exchange (ETDEWEB)

Chi, Hoang Thanh, E-mail: kk086406@mgs.k.u-tokyo.ac.jp [Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639 (Japan); Ly, Bui Thi Kim [Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639 (Japan); Kano, Yasuhiko [Division of Hematology and Medical Oncology, Tochigi Cancer Center, Tochigi 321-0293 (Japan); Tojo, Arinobu [Division of Molecular Therapy, Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo (Japan); Watanabe, Toshiki [Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639 (Japan); Sato, Yuko [Musashimurayama Hospital, Musashimurayama, Tokyo 208-0011 (Japan)

2012-12-07

Highlights: Black-Right-Pointing-Pointer ETV6-NTRK3 is an oncogene with transformation activity in multiple cell lineages. Black-Right-Pointing-Pointer PKC412 could block ETV6-NTRK3 activation. Black-Right-Pointing-Pointer Loss of ETV6-NTRK3 phosphorylation leads to inactivation of its downstream signaling pathway. Black-Right-Pointing-Pointer Inhibition of ETV6-NTRK3 activation by PKC412 could be a novel strategy for the treatment. -- Abstract: The ETV6-NTRK3 (EN) fusion gene which encodes a chimeric tyrosine kinase was first identified by cloning of the t(12;15)(p13;q25) translocation in congenital fibrosarcoma (CFS). Since then, EN has been also found in congenital mesoblastic nephroma (CMN), secretory breast carcinoma (SBC) and acute myelogenous leukemia (AML). Using IMS-M2 and M0-91 cell lines harboring the EN fusion gene, and Ba/F3 cells stably transfected with EN, we demonstrated that PKC412, also known as midostaurin, is an inhibitor of EN. Inhibition of EN activity by PKC412 suppressed the activity of it downstream molecules leading to inhibition of cell proliferation and induction of apoptosis. Our data for the first time suggested that PKC412 could serve as therapeutic drug for treatment of patients with this fusion.

42 CFR 412.304 - Implementation of the capital prospective payment system.

Science.gov (United States)

2010-10-01

... HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Inpatient Hospital Capital Costs General Provisions § 412.304 Implementation of the capital prospective payment system. (a) General rule. As described in §§ 412.312 through 412.370...

The origin of high magnetic properties in (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

Energy Technology Data Exchange (ETDEWEB)

Kobayashi, K., E-mail: koba@ms.sist.ac.jp [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Suzuki, S.; Kuno, T.; Urushibata, K. [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Sakuma, N.; Yano, M.; Shoji, T.; Kato, A. [Toyota Motor Corporation, 1200 Mishuku, Susono, Shizuoka 410-1193 (Japan); Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan); Manabe, A. [Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan)

2017-03-15

Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn{sub 12}-type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe{sub 0.75}Co{sub 0.25}), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti{sub 1.0} to −Ti{sub 0.5}, which increased the Fe and Co content, preserved the ThMn{sub 12} structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe{sub 11}Ti{sub 1.0}N{sub 1.5}, and by 7% for the Co-containing, (Nd{sub 0.7}Zr{sub 0.3}) (Fe{sub 0.75}Co{sub 0.25}) {sub 11.5}Ti{sub 0.5}N{sub 1.3} alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

The R-operator for a modular double

International Nuclear Information System (INIS)

Chicherin, D; Derkachov, S

2014-01-01

We construct the R-operator—the solution of the Yang–Baxter equation acting in the tensor product π s 1 ⊗π s 2 of two infinite-dimensional representations of Faddeev’s modular double. This R-operator intertwines the product of two L-operators associated with the modular double and it is built from three basic operators generating the permutation group of four parameters S 4 . (paper)

42 CFR 412.79 - Determination of the hospital-specific rate for inpatient operating costs for Medicare-dependent...

Science.gov (United States)

2010-10-01

... OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Determination of Transition Period Payment Rates for the Prospective Payment System for Inpatient... § 412.73(c)(14) through (c)(16). (e) DRG adjustment. The applicable hospital-specific cost per discharge...

餐饮业常见生物危害分析及控制%Analysis and control of common biohazard in restaurant industry

Institute of Scientific and Technical Information of China (English)

贺寅; 张连慧; 刘新旗

2013-01-01

餐饮业食品安全问题已逐渐成为政府高度重视、广大消费者日趋关注的大问题.由于生物危害造成致病菌污染食品而导致的食源性疾病仍然占主要位置.因此,生物危害分析在餐饮业HACCP体系(Hazard Analysis and Critical Control Point)建立过程中尤为重要.本文对餐饮业HACCP体系建立过程中常见的3种生物危害:细菌(金黄色葡萄球菌、沙门氏菌、副溶血性弧菌、肠出血性大肠杆菌O157:H7、单核细胞增生李斯特菌、肉毒梭状芽孢杆菌、志贺氏菌、蜡样芽孢杆菌)、病毒、寄生虫生物危害进行科学的分析,并提出切实有效的控制措施,为建立经济高效的HACCP体系提供一定的理论支持.%The food safety issues of restaurant industry have been attached great importance by both government and consumers.The foodborne diseases still occupy the main position due to the Pathogenic bacteria pollution food caused by biohazard.Therefore,the biohazard analysis plays the key role during the process of HACCP( Hazard Analysis and Critical Control Point)construction in the restaurant industry.ln this article,3 common biohazards were analyzed of the process of HACCP construction in the restaurant industry, including bacteria ( Staphylococcus aureus, salmonella, Vibrio parahemolyticus, Intestinal hemorrhagic escherichia coli 0157 : H7, Mononuclear cell hyperplasia liszt bacteria, Clostridium botulinum, Shigella Spp, Bacillus cereus), viruses, parasite. Regulatory measures were proposed which provided theoretical basis in the construction of economic efficient HACCP system.

ETV6–NTRK3 as a therapeutic target of small molecule inhibitor PKC412

International Nuclear Information System (INIS)

Chi, Hoang Thanh; Ly, Bui Thi Kim; Kano, Yasuhiko; Tojo, Arinobu; Watanabe, Toshiki; Sato, Yuko

2012-01-01

Highlights: ► ETV6–NTRK3 is an oncogene with transformation activity in multiple cell lineages. ► PKC412 could block ETV6–NTRK3 activation. ► Loss of ETV6–NTRK3 phosphorylation leads to inactivation of its downstream signaling pathway. ► Inhibition of ETV6–NTRK3 activation by PKC412 could be a novel strategy for the treatment. -- Abstract: The ETV6–NTRK3 (EN) fusion gene which encodes a chimeric tyrosine kinase was first identified by cloning of the t(12;15)(p13;q25) translocation in congenital fibrosarcoma (CFS). Since then, EN has been also found in congenital mesoblastic nephroma (CMN), secretory breast carcinoma (SBC) and acute myelogenous leukemia (AML). Using IMS-M2 and M0–91 cell lines harboring the EN fusion gene, and Ba/F3 cells stably transfected with EN, we demonstrated that PKC412, also known as midostaurin, is an inhibitor of EN. Inhibition of EN activity by PKC412 suppressed the activity of it downstream molecules leading to inhibition of cell proliferation and induction of apoptosis. Our data for the first time suggested that PKC412 could serve as therapeutic drug for treatment of patients with this fusion.

26 CFR 11.412(c)-11 - Election with respect to bonds.

Science.gov (United States)

2010-04-01

... amount payable at maturity (or, in the case of a bond which is callable prior to maturity, the earliest... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Election with respect to bonds. 11.412(c)-11... OF 1974 § 11.412(c)-11 Election with respect to bonds. (a) In general. Section 412(c)(2)(B) provides...

32 CFR 644.412 - Transfer of custody and accountability.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Transfer of custody and accountability. 644.412 Section 644.412 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... Transfer of custody and accountability. The DE will transfer custody and accountability or will coordinate...

Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

Directory of Open Access Journals (Sweden)

Seán Gerard Brosnahan

2014-11-01

Full Text Available Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

Biomedical waste management operating plan. Revision C

Energy Technology Data Exchange (ETDEWEB)

1996-02-14

Recent national incidents involving medical and/or infectious wastes indicated the need for tighter control of medical wastes. Within the last five years, improper management of medical waste resulted in the spread of disease, reuse of needles by drug addicts, and the closing of large sections of public beaches due to medical waste that washed ashore from ocean disposal. Several regulations, both at the federal and state level, govern management (i.e., handling, storage, transport, treatment, and disposal) of solid or liquid waste which may present a threat of infection to humans. This waste, called infectious, biomedical, biohazardous, or biological waste, generally includes non-liquid human tissue and body parts; laboratory waste which contains human disease-causing agents; discarded sharps; human blood, blood products, and other body fluids. The information that follows outlines and summarizes the general requirements of each standard or rule applicable to biohazardous waste management. In addition, it informs employees of risks associated with biohazardous waste management.

Theory versus data: how to calculate R0?

Directory of Open Access Journals (Sweden)

Romulus Breban

2007-03-01

Full Text Available To predict the potential severity of outbreaks of infectious diseases such as SARS, HIV, TB and smallpox, a summary parameter, the basic reproduction number R(0, is generally calculated from a population-level model. R(0 specifies the average number of secondary infections caused by one infected individual during his/her entire infectious period at the start of an outbreak. R(0 is used to assess the severity of the outbreak, as well as the strength of the medical and/or behavioral interventions necessary for control. Conventionally, it is assumed that if R(0>1 the outbreak generates an epidemic, and if R(0<1 the outbreak becomes extinct. Here, we use computational and analytical methods to calculate the average number of secondary infections and to show that it does not necessarily represent an epidemic threshold parameter (as it has been generally assumed. Previously we have constructed a new type of individual-level model (ILM and linked it with a population-level model. Our ILM generates the same temporal incidence and prevalence patterns as the population-level model; we use our ILM to directly calculate the average number of secondary infections (i.e., R(0. Surprisingly, we find that this value of R(0 calculated from the ILM is very different from the epidemic threshold calculated from the population-level model. This occurs because many different individual-level processes can generate the same incidence and prevalence patterns. We show that obtaining R(0 from empirical contact tracing data collected by epidemiologists and using this R(0 as a threshold parameter for a population-level model could produce extremely misleading estimates of the infectiousness of the pathogen, the severity of an outbreak, and the strength of the medical and/or behavioral interventions necessary for control.

42 CFR 412.72 - Modification of base-year costs.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Modification of base-year costs. 412.72 Section 412... Modification of base-year costs. (a) Bases for modification of base-year costs. Base-year costs as determined... before November 16, 1983 has until November 15, 1983 to request its intermediary to reestimate its base...

Orthogonal and symplectic Yangians and Yang–Baxter R-operators

International Nuclear Information System (INIS)

Isaev, A.P.; Karakhanyan, D.; Kirschner, R.

2016-01-01

Yang–Baxter R operators symmetric with respect to the orthogonal and symplectic algebras are considered in an uniform way. Explicit forms for the spinorial and metaplectic R operators are obtained. L operators, obeying the RLL relation with the orthogonal or symplectic fundamental R matrix, are considered in the interesting cases, where their expansion in inverse powers of the spectral parameter is truncated. Unlike the case of special linear algebra symmetry the truncation results in additional conditions on the Lie algebra generators of which the L operators is built and which can be fulfilled in distinguished representations only. Further, generalized L operators, obeying the modified RLL relation with the fundamental R matrix replaced by the spinorial or metaplectic one, are considered in the particular case of linear dependence on the spectral parameter. It is shown how by fusion with respect to the spinorial or metaplectic representation these first order spinorial L operators reproduce the ordinary L operators with second order truncation.

Orthogonal and symplectic Yangians and Yang–Baxter R-operators

Energy Technology Data Exchange (ETDEWEB)

Isaev, A.P., E-mail: isaevap@theor.jinr.ru [Bogoliubov Lab., Joint Institute of Nuclear Research, Dubna (Russian Federation); Karakhanyan, D., E-mail: karakhan@yerphi.am [Yerevan Physics Institute, 2 Alikhanyan br., 0036 Yerevan (Armenia); Kirschner, R., E-mail: Roland.Kirschner@itp.uni-leipzig.de [Institut für Theoretische Physik, Universität Leipzig, PF 100 920, D-04009 Leipzig (Germany)

2016-03-15

Yang–Baxter R operators symmetric with respect to the orthogonal and symplectic algebras are considered in an uniform way. Explicit forms for the spinorial and metaplectic R operators are obtained. L operators, obeying the RLL relation with the orthogonal or symplectic fundamental R matrix, are considered in the interesting cases, where their expansion in inverse powers of the spectral parameter is truncated. Unlike the case of special linear algebra symmetry the truncation results in additional conditions on the Lie algebra generators of which the L operators is built and which can be fulfilled in distinguished representations only. Further, generalized L operators, obeying the modified RLL relation with the fundamental R matrix replaced by the spinorial or metaplectic one, are considered in the particular case of linear dependence on the spectral parameter. It is shown how by fusion with respect to the spinorial or metaplectic representation these first order spinorial L operators reproduce the ordinary L operators with second order truncation.

Orthogonal and symplectic Yangians and Yang–Baxter R-operators

Directory of Open Access Journals (Sweden)

A.P. Isaev

2016-03-01

Full Text Available Yang–Baxter R operators symmetric with respect to the orthogonal and symplectic algebras are considered in an uniform way. Explicit forms for the spinorial and metaplectic R operators are obtained. L operators, obeying the RLL relation with the orthogonal or symplectic fundamental R matrix, are considered in the interesting cases, where their expansion in inverse powers of the spectral parameter is truncated. Unlike the case of special linear algebra symmetry the truncation results in additional conditions on the Lie algebra generators of which the L operators is built and which can be fulfilled in distinguished representations only. Further, generalized L operators, obeying the modified RLL relation with the fundamental R matrix replaced by the spinorial or metaplectic one, are considered in the particular case of linear dependence on the spectral parameter. It is shown how by fusion with respect to the spinorial or metaplectic representation these first order spinorial L operators reproduce the ordinary L operators with second order truncation.

The r-Java 2.0 code: nuclear physics

Science.gov (United States)

Kostka, M.; Koning, N.; Shand, Z.; Ouyed, R.; Jaikumar, P.

2014-08-01

Aims: We present r-Java 2.0, a nucleosynthesis code for open use that performs r-process calculations, along with a suite of other analysis tools. Methods: Equipped with a straightforward graphical user interface, r-Java 2.0 is capable of simulating nuclear statistical equilibrium (NSE), calculating r-process abundances for a wide range of input parameters and astrophysical environments, computing the mass fragmentation from neutron-induced fission and studying individual nucleosynthesis processes. Results: In this paper we discuss enhancements to this version of r-Java, especially the ability to solve the full reaction network. The sophisticated fission methodology incorporated in r-Java 2.0 that includes three fission channels (beta-delayed, neutron-induced, and spontaneous fission), along with computation of the mass fragmentation, is compared to the upper limit on mass fission approximation. The effects of including beta-delayed neutron emission on r-process yield is studied. The role of Coulomb interactions in NSE abundances is shown to be significant, supporting previous findings. A comparative analysis was undertaken during the development of r-Java 2.0 whereby we reproduced the results found in the literature from three other r-process codes. This code is capable of simulating the physical environment of the high-entropy wind around a proto-neutron star, the ejecta from a neutron star merger, or the relativistic ejecta from a quark nova. Likewise the users of r-Java 2.0 are given the freedom to define a custom environment. This software provides a platform for comparing proposed r-process sites.

29 CFR 2580.412-9 - Meaning of fraud or dishonesty.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Meaning of fraud or dishonesty. 2580.412-9 Section 2580.412-9 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT OF LABOR TEMPORARY BONDING RULES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974...

17 CFR 4.12 - Exemption from provisions of part 4.

Science.gov (United States)

2010-04-01

... part 4. 4.12 Section 4.12 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... said Act; (B) Will generally and routinely engage in the buying and selling of securities and securities derived instruments; (C) Will not enter into commodity futures and commodity options contracts for...

Health Monitoring Survey of Bell 412EP Transmissions

Science.gov (United States)

Tucker, Brian E.; Dempsey, Paula J.

2016-01-01

Health and usage monitoring systems (HUMS) use vibration-based Condition Indicators (CI) to assess the health of helicopter powertrain components. A fault is detected when a CI exceeds its threshold value. The effectiveness of fault detection can be judged on the basis of assessing the condition of actual components from fleet aircraft. The Bell 412 HUMS-equipped helicopter is chosen for such an evaluation. A sample of 20 aircraft included 12 aircraft with confirmed transmission and gearbox faults (detected by CIs) and eight aircraft with no known faults. The associated CI data is classified into "healthy" and "faulted" populations based on actual condition and these populations are compared against their CI thresholds to quantify the probability of false alarm and the probability of missed detection. Receiver Operator Characteristic analysis is used to optimize thresholds. Based on the results of the analysis, shortcomings in the classification method are identified for slow-moving CI trends. Recommendations for improving classification using time-dependent receiver-operator characteristic methods are put forth. Finally, lessons learned regarding OEM-operator communication are presented.

C0-semigroups of linear operators on some ultrametric Banach spaces

Directory of Open Access Journals (Sweden)

Toka Diagana

2006-01-01

Full Text Available C0-semigroups of linear operators play a crucial role in the solvability of evolution equations in the classical context. This paper is concerned with a brief conceptualization of C0-semigroups on (ultrametric free Banach spaces E. In contrast with the classical setting, the parameter of a given C0-semigroup belongs to a clopen ball Ωr of the ground field K. As an illustration, we will discuss the solvability of some homogeneous p-adic differential equations.

On the equivalence of different definitions of R-operation

International Nuclear Information System (INIS)

Wegrzyn, P.

1989-01-01

Three well-known definitions of R-operation in the BPHZ formalism are presented. The equivalence between the Zimmermann's forest formula and the factorized version of R-operation is proved. 11 refs. (author)

49 CFR 178.348 - Specification DOT 412; cargo tank motor vehicle.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 412; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.348 Specification DOT 412; cargo tank motor vehicle. ...

Other characterizations of $\\beta$-$\\theta$-R0 topological spaces

OpenAIRE

Miguel Caldas Cueva

2013-01-01

In this paper we give other characterizations of $\\beta$-$\\theta$-$%R_0$ and also introduce a new separation axiom called$\\beta$-$\\theta$-$R_1$. It turns out that $\\beta$-$\\theta$-$R_1$ isstronger that $\\beta$-$\\theta$-$R_0$

26 CFR 1.412(c)(3)-1 - Reasonable funding methods.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Reasonable funding methods. 1.412(c)(3)-1... Reasonable funding methods. (a) Introduction—(1) In general. This section prescribes rules for determining whether or not, in the case of an ongoing plan, a funding method is reasonable for purposes of section 412...

A first survey of the rye (Secale cereale) genome composition through BAC end sequencing of the short arm of chromosome 1R

Czech Academy of Sciences Publication Activity Database

Bartoš, Jan; Paux, E.; Kofler, R.; Havránková, Miroslava; Kopecký, David; Suchánková, Pavla; Šafář, Jan; Šimková, Hana; Town, C.D.; Lelley, T.; Feuillet, C.; Doležel, Jaroslav

2008-01-01

Roč. 8, č. 95 (2008), s. 1-12 ISSN 1471-2229 R&D Projects: GA ČR GP521/06/P412; GA ČR GD521/05/H013; GA MŠk(CZ) LC06004 Institutional research plan: CEZ:AV0Z50380511 Keywords : BAC libraries * flow-sorted chromosomes Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.030, year: 2008

Complete Genome Sequence of Paenibacillus strain Y4.12MC10, a Novel Paenibacillus lautus strain Isolated from Obsidian Hot Spring in Yellowstone National Park.

Science.gov (United States)

Mead, David A; Lucas, Susan; Copeland, Alex; Lapidus, Alla; Cheng, Jan-Feng; Bruce, David C; Goodwin, Lynne A; Pitluck, Sam; Chertkov, Olga; Zhang, Xiaojing; Detter, John C; Han, Cliff S; Tapia, Roxanne; Land, Miriam; Hauser, Loren J; Chang, Yun-Juan; Kyrpides, Nikos C; Ivanova, Natalia N; Ovchinnikova, Galina; Woyke, Tanja; Brumm, Catherine; Hochstein, Rebecca; Schoenfeld, Thomas; Brumm, Phillip

2012-07-30

Paenibacillus sp.Y412MC10 was one of a number of organisms isolated from Obsidian Hot Spring, Yellowstone National Park, Montana, USA under permit from the National Park Service. The isolate was initially classified as a Geobacillus sp. Y412MC10 based on its isolation conditions and similarity to other organisms isolated from hot springs at Yellowstone National Park. Comparison of 16 S rRNA sequences within the Bacillales indicated that Geobacillus sp.Y412MC10 clustered with Paenibacillus species, and the organism was most closely related to Paenibacillus lautus. Lucigen Corp. prepared genomic DNA and the genome was sequenced, assembled, and annotated by the DOE Joint Genome Institute. The genome sequence was deposited at the NCBI in October 2009 (NC_013406). The genome of Paenibacillus sp. Y412MC10 consists of one circular chromosome of 7,121,665 bp with an average G+C content of 51.2%. Comparison to other Paenibacillus species shows the organism lacks nitrogen fixation, antibiotic production and social interaction genes reported in other paenibacilli. The Y412MC10 genome shows a high level of synteny and homology to the draft sequence of Paenibacillus sp. HGF5, an organism from the Human Microbiome Project (HMP) Reference Genomes. This, combined with genomic CAZyme analysis, suggests an intestinal, rather than environmental origin for Y412MC10.

12 CFR 41.2 - Examples.

Science.gov (United States)

2010-01-01

... COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR CREDIT REPORTING General Provisions § 41.2 Examples. The examples in this part are not exclusive. Compliance with an example, to the extent applicable, constitutes compliance with this part. Examples in a paragraph illustrate only the issue described in the...

42 CFR 412.10 - Changes in the DRG classification system.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Changes in the DRG classification system. 412.10... § 412.10 Changes in the DRG classification system. (a) General rule. CMS issues changes in the DRG... after the same date the payment rates are effective. (b) Basis for changes in the DRG classification...

Safe dismantling of the SVAFO research reactors R2 and R2-0 in Sweden

International Nuclear Information System (INIS)

ARNOLD, Hans-Uwe; BROY, Yvonne; Dirk Schneider

2017-01-01

The R2 and R2-0 reactors were part of the Swedish government's research program on nuclear power from the early 1960's. Both reactors were shut down in 2005 following a decision by former operator Studsvik Nuclear AB. The decommissioning of the R2 and R2-0 reactors is divided into three phases. The first phase - awarded to AREVA - involved dismantling of the reactors and associated systems in the reactor pool, treatment of the disassembled components as well as draining, cleaning and emptying the pool. In the second phase, the pool structure itself will be dismantled, while removal of remaining reactor systems, treatment and disposal of materials and clean-up will be carried out in the third stage. The entire work is planned to be completed before the end of this decade. The paper describes the several steps of phase 1 - starting with the team building, followed by the dismantling operations and covers challenges encountered and lessons learned as well. The reactors consist of 5.400 kg aluminum, 6.000 kg stainless steel restraint structures as well as, connection elements of the mostly flanged components (1.000 kg). The most demanding - from a radiological point of view - was the R2-0 reactor that was limited to ∼ 1 m"3 construction volumes but with an extremely heterogeneous activation profile. Based on the calculated radiological entrance data and later sampling, nuclide vectors for both reactors depending on the real placement of the single component and on the material (aluminum and stainless steel) were created. Finally, for the highest activated component from R2 reactor, 85 Sv/h were measured. The dismantling principles - adopted on a safety point of view - were the following: The always protected base area of the ponds served as a flexible buffer area for waste components and packaging. Specific protections were also installed on the walls to protect them from mechanical stress which may occur during dismantling work. A specific work platform was

40 CFR 412.4 - Best management practices (BMPs) for land application of manure, litter, and process wastewater.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Best management practices (BMPs) for... FEEDING OPERATIONS (CAFO) POINT SOURCE CATEGORY § 412.4 Best management practices (BMPs) for land... implement best management practices. Each CAFO subject to this section that land applies manure, litter, or...

File list: His.Emb.50.AllAg.4-12h_embryos [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Emb.50.AllAg.4-12h_embryos dm3 Histone Embryo 4-12h embryos SRX681773,SRX681797...,SRX681793,SRX681769 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Emb.50.AllAg.4-12h_embryos.bed ...

42 CFR 412.374 - Payments to hospitals located in Puerto Rico.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Payments to hospitals located in Puerto Rico. 412... Payment System for Inpatient Hospital Capital Costs Special Rules for Puerto Rico Hospitals § 412.374 Payments to hospitals located in Puerto Rico. (a) FY 1998 through FY 2004. Payments for capital-related...

5 CFR 412.201 - Management succession.

Science.gov (United States)

2010-01-01

... programs must be supported by employee training and development programs. The focus of the program should... learning experiences throughout an employee's career, such as details, mentoring, coaching, learning groups..., MANAGEMENT, AND EXECUTIVE DEVELOPMENT Succession Planning § 412.201 Management succession. The head of each...

eddy4R 0.2.0: a DevOps model for community-extensible processing and analysis of eddy-covariance data based on R, Git, Docker, and HDF5

Science.gov (United States)

Metzger, Stefan; Durden, David; Sturtevant, Cove; Luo, Hongyan; Pingintha-Durden, Natchaya; Sachs, Torsten; Serafimovich, Andrei; Hartmann, Jörg; Li, Jiahong; Xu, Ke; Desai, Ankur R.

2017-08-01

Large differences in instrumentation, site setup, data format, and operating system stymie the adoption of a universal computational environment for processing and analyzing eddy-covariance (EC) data. This results in limited software applicability and extensibility in addition to often substantial inconsistencies in flux estimates. Addressing these concerns, this paper presents the systematic development of portable, reproducible, and extensible EC software achieved by adopting a development and systems operation (DevOps) approach. This software development model is used for the creation of the eddy4R family of EC code packages in the open-source R language for statistical computing. These packages are community developed, iterated via the Git distributed version control system, and wrapped into a portable and reproducible Docker filesystem that is independent of the underlying host operating system. The HDF5 hierarchical data format then provides a streamlined mechanism for highly compressed and fully self-documented data ingest and output. The usefulness of the DevOps approach was evaluated for three test applications. First, the resultant EC processing software was used to analyze standard flux tower data from the first EC instruments installed at a National Ecological Observatory (NEON) field site. Second, through an aircraft test application, we demonstrate the modular extensibility of eddy4R to analyze EC data from other platforms. Third, an intercomparison with commercial-grade software showed excellent agreement (R2 = 1.0 for CO2 flux). In conjunction with this study, a Docker image containing the first two eddy4R packages and an executable example workflow, as well as first NEON EC data products are released publicly. We conclude by describing the work remaining to arrive at the automated generation of science-grade EC fluxes and benefits to the science community at large. This software development model is applicable beyond EC and more generally builds

42 CFR 412.20 - Hospital services subject to the prospective payment systems.

Science.gov (United States)

2010-10-01

... payment systems. 412.20 Section 412.20 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Hospital Services Subject to and Excluded From the Prospective Payment Systems for Inpatient...

Gauge-adjusted rainfall estimates from commercial microwave links

Directory of Open Access Journals (Sweden)

M. Fencl

2017-01-01

experimental layouts of ground truth from rain gauges (RGs with different spatial and temporal resolutions. The results suggest that CMLs adjusted by RGs with a temporal aggregation of up to 1 h (i provide precise high-resolution QPEs (relative error  < 7 %, Nash–Sutcliffe efficiency coefficient  >  0.75 and (ii that the combination of both sensor types clearly outperforms each individual monitoring system. Unfortunately, adjusting CML observations to RGs with longer aggregation intervals of up to 24 h has drawbacks. Although it substantially reduces bias, it unfavourably smoothes out rainfall peaks of high intensities, which is undesirable for stormwater management. A similar, but less severe, effect occurs due to spatial averaging when CMLs are adjusted to remote RGs. Nevertheless, even here, adjusted CMLs perform better than RGs alone. Furthermore, we provide first evidence that the joint use of multiple CMLs together with RGs also reduces bias in their QPEs. In summary, we believe that our adjustment method has great potential to improve the space–time resolution of current urban rainfall monitoring networks. Nevertheless, future work should aim to better understand the reason for the observed systematic error in QPEs from CMLs.

29 CFR 2580.412-29 - Exemption.

Science.gov (United States)

2010-07-01

... Exemptions Savings and Loan Associations Subject to Federal Regulation § 2580.412-29 Exemption. An exemption... Act is granted whereby savings and loan associations (including building and loan associations... for the benefit of their own employees, where such a savings and loan association is the administrator...

20 CFR 658.412 - Complaint resolution.

Science.gov (United States)

2010-04-01

... Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Job Service Complaint System State Agency Js Complaint System § 658.412... satisfaction with the outcome, or (2) The complainant chooses not to elevate the complaint to the next level of...

Crystallization and preliminary X-ray crystallographic analysis of SMU.412c protein from the caries pathogen Streptococcus mutans

International Nuclear Information System (INIS)

Ye, Zhao-Yang; Hou, Qiao-Ming; Li, Lan-Fen; Su, Xiao-Dong

2009-01-01

Crystallization of SMU.412c protein from the caries pathogen Streptococcus mutans can easily appear in the condition 2.8 M sodium acetate pH 7.0 and its crystal belongs to space group P4 1 2 1 2. The smu.412c gene encodes a putative histidine triad-like protein (SMU.412c) with 139 residues that is involved in cell-cycle regulation in Streptococcus mutans. The gene was cloned into the expression vector pET28a and subsequently expressed in Escherichia coli strain BL21 (DE3) to give a substantially soluble form of SMU.412c with a His 6 tag at its N-terminus. The recombinant protein was purified to homogeneity in a two-step procedure involving Ni 2+ -chelating and size-exclusion chromatography. Crystals suitable for X-ray diffraction were obtained using the sitting-drop vapour-diffusion method and diffracted to 1.8 Å resolution on beamline BL6A at Photon Factory, Tsukuba, Japan. The crystal belonged to space group P4 1 2 1 2, with unit-cell parameters a = b = 53.5, c = 141.1 Å

42 CFR 412.370 - General provisions for hospitals located in Puerto Rico.

Science.gov (United States)

2010-10-01

... Prospective Payment System for Inpatient Hospital Capital Costs Special Rules for Puerto Rico Hospitals § 412.370 General provisions for hospitals located in Puerto Rico. Except as provided in § 412.374, hospitals located in Puerto Rico are subject to the rules in this subpart governing the prospective payment...

42 CFR 412.73 - Determination of the hospital-specific rate based on a Federal fiscal year 1982 base period.

Science.gov (United States)

2010-10-01

... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR... System for Inpatient Operating Costs § 412.73 Determination of the hospital-specific rate based on a... under the Social Security Act as in effect on April 19, 1983. (e) DRG adjustment. The applicable...

42 CFR 412.604 - Conditions for payment under the prospective payment system for inpatient rehabilitation facilities.

Science.gov (United States)

2010-10-01

... payment system for inpatient rehabilitation facilities. 412.604 Section 412.604 Public Health CENTERS FOR... SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment for Inpatient Rehabilitation Hospitals and Rehabilitation Units § 412.604 Conditions for payment under the prospective payment system for inpatient...

Integration of Biosafety into Core Facility Management

Science.gov (United States)

Fontes, Benjamin

2013-01-01

This presentation will discuss the implementation of biosafety policies for small, medium and large core laboratories with primary shared objectives of ensuring the control of biohazards to protect core facility operators and assure conformity with applicable state and federal policies, standards and guidelines. Of paramount importance is the educational process to inform core laboratories of biosafety principles and policies and to illustrate the technology and process pathways of the core laboratory for biosafety professionals. Elevating awareness of biohazards and the biosafety regulatory landscape among core facility operators is essential for the establishment of a framework for both project and material risk assessment. The goal of the biohazard risk assessment process is to identify the biohazard risk management parameters to conduct the procedure safely and in compliance with applicable regulations. An evaluation of the containment, protective equipment and work practices for the procedure for the level of risk identified is facilitated by the establishment of a core facility registration form for work with biohazards and other biological materials with potential risk. The final step in the biocontainment process is the assumption of Principal Investigator role with full responsibility for the structure of the site-specific biosafety program plan by core facility leadership. The presentation will provide example biohazard protocol reviews and accompanying containment measures for core laboratories at Yale University.

42 CFR 412.125 - Effect of change of ownership on payments under the prospective payment systems.

Science.gov (United States)

2010-10-01

... prospective payment systems. 412.125 Section 412.125 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Payments to Hospitals Under the Prospective Payment Systems § 412.125 Effect of change of...

412th Test Engineering Group Vision for Future Knowledge Management (KM)

Science.gov (United States)

2018-05-17

Presentation 3. DATES COVERED (From - To) 17 May 2018 4. TITLE AND SUBTITLE 412th Test Engineering Group Vision for Future Knowledge Management (KM... Engineering Group 307 E. Popson Ave Edwards AFB, CA 93523 8. PERFORMING ORGANIZATION REPORT NUMBER 412TW-PA...centers for the TENG test customers to allow the data to be readily available within minutes of a flight, for the data to be organized so that the engineer

Tensor operators in R-matrix approach

International Nuclear Information System (INIS)

Bytsko, A.G.; Rossijskaya Akademiya Nauk, St. Petersburg

1995-12-01

The definitions and some properties (e.g. the Wigner-Eckart theorem, the fusion procedure) of covariant and contravariant q-tensor operators for quasitriangular quantum Lie algebras are formulated in the R-matrix language. The case of U q (sl(n)) (in particular, for n=2) is discussed in more detail. (orig.)

R2/R0-WTR decommissioning cost. Comparison and benchmarking analysis

International Nuclear Information System (INIS)

Varley, Geoff; Rusch, Chris

2001-10-01

SKI charged NAC International with the task of determining whether or not the decommissioning cost estimates of R2/R0 (hereafter simply referred to as R2) and Aagesta research reactors are reasonable. The associated work was performed in two phases. The objective in Phase I was to make global comparisons of the R2 and Aagesta decommissioning estimates with the estimates/actual costs for the decommissioning of similar research reactors in other countries. This report presents the results of the Phase II investigations. Phase II focused on selected discrete work packages within the decommissioning program of the WTR reactor. To the extent possible a comparison of those tasks with estimates for the R2 reactor has been made, as a basis for providing an opinion on the reasonableness of the R2 estimate. The specific WTR packages include: reactor vessel and internals dismantling; biological shield dismantling; primary coolant piping dismantling; electrical equipment removal; waste packaging; transportation and disposal of radioactive concrete and reactor components; project management, licensing and engineering; and removal of ancillary facilities. The specific tasks were characterised and analysed in terms of fundamental parameters including: task definition; labour hours expended; labour cost; labour productivity; length of work week; working efficiency; working environment and impact on job execution; external costs (contract labour, materials and equipment); total cost; waste volumes; and waste packaging and transport costs. Based on such detailed raw data, normalised unit resources have been derived for selected parts of the decommissioning program, as a first step towards developing benchmarking data for D and D activities at research reactors. Several general conclusions emerged from the WTR decommissioning project. Site characterisation can confirm or negate major assumptions, quantify waste volumes, delineate obstacles to completing work, provide an understanding

The basic reproduction number (R0) of measles: a systematic review.

Science.gov (United States)

Guerra, Fiona M; Bolotin, Shelly; Lim, Gillian; Heffernan, Jane; Deeks, Shelley L; Li, Ye; Crowcroft, Natasha S

2017-12-01

The basic reproduction number, R nought (R 0 ), is defined as the average number of secondary cases of an infectious disease arising from a typical case in a totally susceptible population, and can be estimated in populations if pre-existing immunity can be accounted for in the calculation. R 0 determines the herd immunity threshold and therefore the immunisation coverage required to achieve elimination of an infectious disease. As R 0 increases, higher immunisation coverage is required to achieve herd immunity. In July, 2010, a panel of experts convened by WHO concluded that measles can and should be eradicated. Despite the existence of an effective vaccine, regions have had varying success in measles control, in part because measles is one of the most contagious infections. For measles, R 0 is often cited to be 12-18, which means that each person with measles would, on average, infect 12-18 other people in a totally susceptible population. We did a systematic review to find studies reporting rigorous estimates and determinants of measles R 0 . Studies were included if they were a primary source of R 0 , addressed pre-existing immunity, and accounted for pre-existing immunity in their calculation of R 0 . A search of key databases was done in January, 2015, and repeated in November, 2016, and yielded 10 883 unique citations. After screening for relevancy and quality, 18 studies met inclusion criteria, providing 58 R 0 estimates. We calculated median measles R 0 values stratified by key covariates. We found that R 0 estimates vary more than the often cited range of 12-18. Our results highlight the importance of countries calculating R 0 using locally derived data or, if this is not possible, using parameter estimates from similar settings. Additional data and agreed review methods are needed to strengthen the evidence base for measles elimination modelling. Copyright © 2017 Elsevier Ltd. All rights reserved.

78 FR 29393 - University of Missouri-Columbia Facility Operating License No. R-103

Science.gov (United States)

2013-05-20

... Facility Operating License No. R-103 AGENCY: Nuclear Regulatory Commission. ACTION: License renewal... the renewal of Facility Operating License No. R-103 (``Application''), which currently authorizes the... application for the renewal of Facility Operating License No. R-103, which, currently authorizes the licensee...

PKC 412 sensitizes U1810 non-small cell lung cancer cells to DNA damage

International Nuclear Information System (INIS)

Hemstroem, Therese H.; Joseph, Bertrand; Schulte, Gunnar; Lewensohn, Rolf; Zhivotovsky, Boris

2005-01-01

Non-small cell lung carcinoma (NSCLC) is characterized by resistance to drug-induced apoptosis, which might explain the survival of lung cancer cells following treatment. Recently we have shown that the broad-range kinase inhibitor staurosporine (STS) reactivates the apoptotic machinery in U1810 NSCLC cells [Joseph et al., Oncogene 21 (2002) 65]. Lately, several STS analogs that are more specific in kinase inhibition have been suggested for tumor treatment. In this study the apoptosis-inducing ability of the STS analogs PKC 412 and Ro 31-8220 used alone or in combination with DNA-damaging agents in U1810 cells was investigated. In these cells Ro 31-8220 neither induced apoptosis when used alone, nor sensitized cells to etoposide treatment. PKC 412 as a single agent induced death of a small number of U1810 cells, whereas it efficiently triggered a dose- and time-dependent apoptosis in U1285 small cell lung carcinoma cells. In both cell types PKC 412 triggered release of mitochondrial proteins followed by caspase activation. However, concomitant activation of a caspase-independent pathway was essential to kill NSCLC cells. Importantly, PKC 412 was able to sensitize etoposide- and radiation-induced death of U1810 cells. The best sensitization was achieved when PKC 412 was administered 24 h after treatments. In U1810 cells, Ro 31-8220 decreased PMA-induced ERK phosphorylation as efficiently as PKC 412, indicating that the failure of Ro 31-8220 to induce apoptosis was not due to weaker inhibition of conventional and novel PKC isoforms. However, Ro 31-8220 increased the basal level of ERK and Akt phosphorylation in both cell lines, whereas Akt phosphorylation was suppressed in the U1810 cells, which might influence apoptosis. These results suggest that PKC 412 could be a useful tool in increasing the efficiency of therapy of NSCLC

34 CFR 412.1 - What is the National Network for Curriculum Coordination in Vocational and Technical Education?

Science.gov (United States)

2010-07-01

... Coordination in Vocational and Technical Education? 412.1 Section 412.1 Education Regulations of the Offices of... EDUCATION NATIONAL NETWORK FOR CURRICULUM COORDINATION IN VOCATIONAL AND TECHNICAL EDUCATION General § 412.1 What is the National Network for Curriculum Coordination in Vocational and Technical Education? The...

42 CFR 412.505 - Conditions for payment under the prospective payment system for long-term care hospitals.

Science.gov (United States)

2010-10-01

... payment system for long-term care hospitals. 412.505 Section 412.505 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Long-Term Care Hospitals § 412.505 Conditions for...

Range of the radiation monitor for the rigid vent of primary containment during normal and emergency operation for a BWR-5 in Laguna Verde

International Nuclear Information System (INIS)

Tijerina S, F.; Pozos S, A. M.; Cabrera U, S.; Mata A, J. A.; Sandoval V, S.; Ovando C, R.; Vargas A, A.; Gallardo R, I.; Cruz G, M.; Amador C, C.

2014-10-01

The earthquake followed by a tsunami, happened in March, 2011 in the coasts of oriental Japan, caused damages in the nuclear power plants 1 at 4 of Fukushima Daiichi leading to damage of the fuel in three of the reactors and to the radiation liberation to the exterior. As consequence of those events, the regulations requires that the power plants with Primary Containment type Mark I and II evaluate to have a system of rigid vent with a monitoring equipment of radiation effluents. The present work covers the rigid vent of diameter 12 of the Primary Containment, type Mark-II, of nuclear power plant of Laguna Verde in conditions of severe accident and normal operation, low regime of Extended Power Up rate (EPU - 2317 MWt), using the codes MAAP3B, MICROSHILED 5.05 and the Bardach Black Boxes methodology. As a result the measurement range of the radiation monitor that is required for monitoring the gassy liberation to the atmosphere was determined. The conclusion is that the superior limit of the range of the radiation meter during a Severe Accident is of 8.55 E + 05 R/h (8.55 E + 08 m R/h) and the superior limit in normal operation of 1.412 E-11 at 2.540 E-7 R/h (1.412 E-14 at 2.540 E-10 m R/h). (Author)

48 CFR 9904.412 - Cost accounting standard for composition and measurement of pension cost.

Science.gov (United States)

2010-10-01

... accounting standard for composition and measurement of pension cost. ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Cost accounting standard for composition and measurement of pension cost. 9904.412 Section 9904.412 Federal Acquisition...

Intraoperative platelet and plasma improves survival in patients operated for a rAAA: a follow-up evaluation

DEFF Research Database (Denmark)

Johansson, Per Ingemar; Swiatek, F.; Jorgensen, L.

2008-01-01

OBJECTIVES: Continued haemorrhage remains a significant contributor to mortality in massively transfused patients. We found that early administration of platelets and plasma reduced mortality from 54% to 36% in rAAA patients. The aim of the present evaluation was to evaluate whether reduced...... mortality in rAAA patients related to a pro-active transfusion therapy is maintained. DESIGN: Single-centre observational study. METHODS: Mortality of patients operated for rAAA 2006-07 was compared to that of patients operated 2004-05 (intervention group; n=50) and 2002-04 (control group, n=82). RESULTS......: 64 consecutive patients with rAAA received, similar to the intervention group, more platelets (5 and 4 vs. 0 units, P

42 CFR 412.521 - Basis of payment.

Science.gov (United States)

2010-10-01

... PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Long-Term Care Hospitals § 412.521 Basis of payment. (a) Method of payment. (1) Under the prospective payment system, long... furnished to Medicare beneficiaries. (2) The amount of payment under the prospective payment system is based...

Effect of PKC412, an inhibitor of protein kinase C, on spontaneous metastatic model mice.

Science.gov (United States)

Nakamura, Kazuki; Yoshikawa, Noriko; Yamaguchi, Yu; Kagota, Satomi; Shinozuka, Kazumasa; Kunitomo, Masaru

2003-01-01

We investigated the anti-metastatic effect of PKC412, a selective inhibitor of protein kinase C (PKC), on a spontaneous metastatic mouse model, which was prepared by inoculation with B16-BL6 mouse melanoma cells into the footpad of the right hind leg. At two weeks after inoculation, the primary tumor was amputated completely. PKC412 (200 mg/kg) administered orally for four weeks after the tumor inoculation, significantly prolonged survival compared with the control. Furthermore, to elucidate the mechanism of the anti-metastatic effect of PKC412, we examined the growth rate of B16-BL6 cells premixed with Matrigel in vivo and the invasiveness of B16-BL6 cells using a chemo-invasion chamber in vitro. PKC412 significantly reduced the growth rate of cells in vivo (100 and 200 mg/kg) and the invading cells in vitro (10, 30 and 100 nM) in a dose-dependent manner. Thus, PKC412 exerts an anti-metastatic action through inhibition of the invasiveness of melanoma cells in the extracellular matrix.

42 CFR 412.620 - Patient classification system.

Science.gov (United States)

2010-10-01

...-mix group classifications and weighting factors. We may periodically adjust the case-mix groups and... rehabilitation facilities into mutually exclusive case-mix groups. (2) For purposes of this subpart, case-mix... assessments under § 412.610(c)(1) are used to classify a Medicare patient into an appropriate case-mix group...

31 CFR 537.412 - Investments in entities involved in economic development projects in Burma.

Science.gov (United States)

2010-07-01

... economic development projects in Burma. 537.412 Section 537.412 Money and Finance: Treasury Regulations... economic development of resources located in Burma is prohibited by § 537.204 where the company's profits are predominantly derived from the company's economic development of resources located in Burma. (b...

42 CFR 412.87 - Additional payment for new medical services and technologies: General provisions.

Science.gov (United States)

2010-10-01

... payment for new medical services and technologies: General provisions. (a) Basis. Sections 412.87 and 412... establish a mechanism to recognize the costs of new medical services and technologies under the hospital... that are new medical services and technologies, if the following conditions are met: (1) A new medical...

29 CFR 2580.412-30 - Conditions of exemption.

Science.gov (United States)

2010-07-01

... BONDING RULES Exemptions Savings and Loan Associations Subject to Federal Regulation § 2580.412-30 Conditions of exemption. This exemption applies only to those savings and loan associations (including building and loan associations, cooperative banks and homestead associations) subject to regulation and...

77 FR 43542 - Cost Accounting Standards: Cost Accounting Standards 412 and 413-Cost Accounting Standards...

Science.gov (United States)

2012-07-25

... rule that revised Cost Accounting Standard (CAS) 412, ``Composition and Measurement of Pension Cost... Accounting Standards: Cost Accounting Standards 412 and 413--Cost Accounting Standards Pension Harmonization Rule AGENCY: Cost Accounting Standards Board, Office of Federal Procurement Policy, Office of...

42 CFR 412.432 - Method of payment under the inpatient psychiatric facility prospective payment system.

Science.gov (United States)

2010-10-01

... facility prospective payment system. 412.432 Section 412.432 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Inpatient Hospital Services of Inpatient...

Sm{sub 0.5}Sr{sub 0.5}CoO{sub 3}+Sm{sub 0.2}Ce{sub 0.8}O{sub 1.9} composite cathode for cermet supported thin Sm{sub 0.2}Ce{sub 0.8}O{sub 1.9} electrolyte SOFC operating below 600{sup o}C

Energy Technology Data Exchange (ETDEWEB)

Zhang, Xinge; Robertson, Mark; Yick, Sing; Deces-Petit, Cyrille; Styles, Edward; Qu, Wei; Xie, Yongsong; Hui, Rob; Roller, Justin; Kesler, Olivera; Maric, Radenka; Ghosh, Dave [Institute for Fuel Cell Innovation, National Research Council Canada, 3250 East Mall, Vancouver, BC (Canada V6T 1W5)

2006-10-06

The cathode is a key component in low temperature solid oxide fuel cells. In this study, composite cathode, 75wt.% Sm{sub 0.5}Sr{sub 0.5}CoO{sub 3} (SSC)+25wt.% Sm{sub 0.2}Ce{sub 0.8}O{sub 1.9} (SDC), was applied on the cermet supported thin SDC electrolyte cell which was fabricated by tape casting, screen-printing, and co-firing. Single cells with the composite cathodes sintered at different temperatures were tested from 400 to 650{sup o}C. The best cell performance, 0.75Wcm{sup -2} peak power operating at 600{sup o}C, was obtained from the 1050{sup o}C sintered cathode. The measured thin SDC electrolyte resistance R{sub s} was 0.128{omega}cm{sup 2} and total electrode polarization R{sub p}(a+c) was only 0.102{omega}cm{sup 2} at 600{sup o}C. (author)

lumpR 2.0.0: an R package facilitating landscape discretisation for hillslope-based hydrological models

Science.gov (United States)

Pilz, Tobias; Francke, Till; Bronstert, Axel

2017-08-01

The characteristics of a landscape pose essential factors for hydrological processes. Therefore, an adequate representation of the landscape of a catchment in hydrological models is vital. However, many of such models exist differing, amongst others, in spatial concept and discretisation. The latter constitutes an essential pre-processing step, for which many different algorithms along with numerous software implementations exist. In that context, existing solutions are often model specific, commercial, or depend on commercial back-end software, and allow only a limited or no workflow automation at all. Consequently, a new package for the scientific software and scripting environment R, called lumpR, was developed. lumpR employs an algorithm for hillslope-based landscape discretisation directed to large-scale application via a hierarchical multi-scale approach. The package addresses existing limitations as it is free and open source, easily extendible to other hydrological models, and the workflow can be fully automated. Moreover, it is user-friendly as the direct coupling to a GIS allows for immediate visual inspection and manual adjustment. Sufficient control is furthermore retained via parameter specification and the option to include expert knowledge. Conversely, completely automatic operation also allows for extensive analysis of aspects related to landscape discretisation. In a case study, the application of the package is presented. A sensitivity analysis of the most important discretisation parameters demonstrates its efficient workflow automation. Considering multiple streamflow metrics, the employed model proved reasonably robust to the discretisation parameters. However, parameters determining the sizes of subbasins and hillslopes proved to be more important than the others, including the number of representative hillslopes, the number of attributes employed for the lumping algorithm, and the number of sub-discretisations of the representative hillslopes.

76 FR 39156 - R. J. Corman Railroad Company/Bardstown Line-Lease and Operation Exemption-R. J. Corman Railroad...

Science.gov (United States)

2011-07-05

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35364] R. J. Corman Railroad Company/Bardstown Line--Lease and Operation Exemption--R. J. Corman Railroad Property, LLC R. J... notice of exemption under 49 CFR 1150.41 to lease from R. J. Corman Railroad Property, LLC (RJC Railroad...

29 CFR 2580.412-8 - The nature of the duties or activities to which the bonding requirement relates.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false The nature of the duties or activities to which the bonding requirement relates. 2580.412-8 Section 2580.412-8 Labor Regulations Relating to Labor (Continued) EMPLOYEE... INCOME SECURITY ACT OF 1974 TEMPORARY BONDING RULES Scope and Form of the Bond § 2580.412-8 The nature of...

29 CFR 2550.412-1 - Temporary bonding requirements.

Science.gov (United States)

2010-07-01

... welfare benefit plan or of any employee pension benefit plan subject to this Act who handle funds or other... in section 412 of the Act, and the terms “employee welfare benefit plan” and “employee pension...-1 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION...

Main-Memory Operation Buffering for Efficient R-Tree Update

DEFF Research Database (Denmark)

Jensen, Christian Søndergaard; Saltenis, Simonas; Biveinis, Laurynas

2007-01-01

the buffering of update operations in main memory as well as the grouping of operations to reduce disk I/O. In particular, operations are performed in bulk so that multiple operations are able to share I/O. The paper presents an analytical cost model that is shown to be accurate by empirical studies...... the main memory that is indeed available, or do not support some of the standard index operations. Assuming a setting where the index updates need not be written to disk immediately, we propose an R-tree-based indexing technique that does not exhibit any of these drawbacks. This technique exploits...

75 FR 18254 - R.J. Corman Railroad Company/Bardstown Line-Lease and Operation Exemption-R.J. Corman Railroad...

Science.gov (United States)

2010-04-09

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [STB Finance Docket No. 35364] R.J. Corman Railroad Company/Bardstown Line--Lease and Operation Exemption--R.J. Corman Railroad Property, LLC R.J. Corman Railroad Company/Bardstown Line (RJC Railroad Company), a Class III rail carrier, has...

Receiver Operator Characteristic Tools Graphic User Interface Extension for R Commander

Directory of Open Access Journals (Sweden)

Daniel Corneliu LEUCUŢA

2015-12-01

Full Text Available Background: Receiver Operator Characteristic (ROC curve, is a graphical plot which presents the performance of a binary classifier when the discrimination cutoff is varied. The aim of this work was to create an extension for R Commander that offers a graphical user interface for Receiver Operator Characteristic tools provided by several existing command line accessible packages like pROC and ROCR. Material and Methods: The extension was built and tested with R version 3.2.0 and R Commander 2.1-7. Results: We built an extension called RcmdrPlugin.ROC that we uploaded on the CRAN servers. The extension adds a new menu called ROC, along with two submenus pROC and ROCR that broadly corresponds to commands available to access the functions of these packages. The pROC menu offers several commands: to plot a ROC curve for a dataset or for a logistic regression model, to compare paired and unpaired ROC curves, each providing the following tabs: General (to select the variables for the analysis, and options for switching cases with controls; Smoothing (allowing the user to select different types of smoothing – binominal, density, distributions like normal, lognormal, ...; AUC (to specify the partial area under the curve (AUC options, CI (to select the options of confidence intervals (CI – the level, computing method: DeLong, bootstrap, ...; Plot (for the plotting options. The ROCR dialogue window offers more options in choosing the performance measures for the plot. Conclusion: The RcmdrPlugin.ROC extension helps less advanced users of R accessing ROC tools in a friendly graphical user interface.

40 CFR 412.44 - Effluent limitations attainable by the application of the best conventional pollutant control...

Science.gov (United States)

2010-07-01

... application of the best conventional pollutant control technology (BCT). 412.44 Section 412.44 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS CONCENTRATED ANIMAL... limitations attainable by the application of the best conventional pollutant control technology (BCT). Except...

40 CFR 412.32 - Effluent limitations attainable by the application of the best conventional pollutant control...

Science.gov (United States)

2010-07-01

... application of the best conventional pollutant control technology (BCT). 412.32 Section 412.32 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS CONCENTRATED ANIMAL... Effluent limitations attainable by the application of the best conventional pollutant control technology...

Aortocaval fistula (ACF) in patients operated for ruptured aortic aneurysm (rAAA)

DEFF Research Database (Denmark)

Warning, Karina; Houlind, Kim Christian; Ravn, Hans

Aortocaval fistula (ACF) in patients operated for Ruptured Acute Aorta Aneurysm (rAAA): A surgical challenge. Introduction Aortocaval fistula is a rare complication of abdominal aortic aneurysm (AAA). It been reported to be present in less than 1% of all AAAs. ACF arise in patients with large...... aneurysms and is typically discovered peroperatively in patients with rAAA. Open surgical treatment is associated with high mortality and morbidity. ACF is a result of spontaneously rupture of large atherosclerotic aneurysms into the inferior vena cava in 80%, 15% arise after trauma and 5% are iatrogenic....... Patients During the last 9 month, we have operated three cases with rAAA and ACF. All patients had an open, acute operation. All ACFs detected during operation. Common for all operations was that the patients had large aneurysms (>10 cm) and extensive bleeding (3-4 l) immediately when the aneurysm...

Glass operational file. Operational models and integration calculations

International Nuclear Information System (INIS)

Ribet, I.

2004-01-01

This document presents the operational choices of dominating phenomena, hypotheses, equations and numerical data of the parameters used in the two operational models elaborated for the calculation of the glass source terms with respect to the waste packages considered: existing packages (R7T7, AVM and CEA glasses) and future ones (UOX2, UOX3, UMo, others). The overall operational choices are justified and demonstrated and a critical analysis of the approach is systematically proposed. The use of the operational model (OPM) V 0 → V r , realistic, conservative and robust, is recommended for glasses with a high thermal and radioactive load, which represent the main part of the vitrified wastes. The OPM V 0 S, much more overestimating but faster to parameterize, can be used for the long-term behaviour forecasting of glasses with low thermal and radioactive load, considering today's lack of knowledge for the parameterization of a V 0 → V r type OPM. Efficiency estimations have been made for R7T7 glasses (OPM V 0 → V r ) and AVM glasses (OPM V 0 S), which correspond to more than 99.9% of the vitrified waste packages activity. The very contrasted results obtained, illustrate the importance of the choice of operational models: in conditions representative of a geologic disposal, the estimation of R7T7-type package lifetime exceeds several hundred thousands years. Even if the estimated lifetime of AVM packages is much shorter (because of the overestimating character of the OPM V 0 S), the release potential radiotoxicity is of the same order as the one of R7T7 packages. (J.S.)

Validation Test Report for the Automated Optical Processing System (AOPS) Version 4.12

Science.gov (United States)

2015-09-03

Sensor (SeaWiFS), Moderate Resolution Imaging Spectrometers ( MODIS on Aqua), and Medium Resolution Imaging Spectrometer (MERIS). This VTR documents...the MOBY site. 3.2.1 Image to Image Comparison The AOPS v4.12 upgrades are detailed in Section 2 System Description. Figure 5 shows the MODIS ...bottom images were processed with AOPS v4.12; MODIS imagery on the left and VIIRS on the right. The most significant change in the VIIRS imagery is

Data Qualification Report For: Thermodynamic Data File, DATA0.YMP.R0 For Geochemical Code, EQ3/6?

International Nuclear Information System (INIS)

P.L. Cloke

2000-09-01

The objective of this work is to evaluate the adequacy of chemical thermodynamic data provided by Lawrence Livermore National Laboratory (LLNL) as DataO.ymp.ROA in response to an input request submitted under AP-3.14Q. This request specified that chemical thermodynamic data available in the file, Data0.com.R2, be updated, improved, and augmented for use in geochemical modeling used in Process Model Reports (PMRs) for Engineered Barrier Systems, Waste Form, Waste Package, Unsaturated Zone, and Near Field Environment, as well as for Performance Assessment. The data are qualified in the temperature range 0 to 100 C. Several Data Tracking Numbers (DTNs) associated with Analysis/Model Reports (AMR) addressing various aspects of the post-closure chemical behavior of the waste package and the Engineered Barrier System that rely on EQ316 outputs to which these data are used as input, are Principal Factor affecting. This qualification activity was accomplished in accordance with the AP-SIII.2Q using the Technical Assessment method. A development plan, TDP-EBS-MD-000044, was prepared in accordance with AP-2.13Q and approved by the Responsible Manager. In addition, a Process Control Evaluation was performed in accordance with AP-SV.1Q. The qualification method, selected in accordance with AP-SIII.2Q, was Technical Assessment. The rationale for this approach is that the data in File Data0.com.R2 are considered Handbook data and therefore do not themselves require qualification. Only changes to Data0.com.R2 required qualification. A new file has been produced which contains the database Data0.ymp.R0, which is recommended for qualification as a result of this action. Data0.ymp.R0 will supersede Data0.com.R2 for all Yucca Mountain Project (YMP) activities

42 CFR 412.105 - Special treatment: Hospitals that incur indirect costs for graduate medical education programs.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Special treatment: Hospitals that incur indirect costs for graduate medical education programs. 412.105 Section 412.105 Public Health CENTERS FOR... SYSTEMS FOR INPATIENT HOSPITAL SERVICES Special Treatment of Certain Facilities Under the Prospective...

Enterprise 2.0 - hvordan får du succes?

DEFF Research Database (Denmark)

Ivang, Reimer

2009-01-01

Det seneste år til halvandet har der været konstant stigende fokus og interesse for begrebet Enterprise 2.0. En interesse som kan ses af den konstant stigende litteratur som beskæftiger sig med emnet. Men er det noget for dig, for din organisation? Få svaret her.......Det seneste år til halvandet har der været konstant stigende fokus og interesse for begrebet Enterprise 2.0. En interesse som kan ses af den konstant stigende litteratur som beskæftiger sig med emnet. Men er det noget for dig, for din organisation? Få svaret her....

The optimum operating conditions of the phased double-rotor facility at the et-R R-1 reactor. Vol. 2

Energy Technology Data Exchange (ETDEWEB)

Naguib, K; Habib, N; Kilany, M; Adib, M [Reactor and Neutron Physics Department, Nuclear Research Center, AEA., Cairo (Egypt); Wahba, M [Dept. of Engineering Physics and Mathematics, Faculty of Engineering, Ain Shams University, Cairo (Egypt)

1996-03-01

The pulsed neutron polyenergetic thermal beam at ET-R R-1 is produced by a phased double-rotor facility. One of the rotors has two diametrically opposite curved slots, while the second is designed to operate as a rotating collimator, the dimensions of the phased rotating collimator are selected to match the curved slot rotor. The calculated collimator transmissions at different operating conditions are found to be in good agreement with the experimental ones. The optimum operating conditions of double-rotor facility are deduced. The calculations were carried out using a computer programme RCOL. The RCOL was designed in Fortran-77 to operate on PCs. 6 figs.

The optimum operating conditions of the phased double-rotor facility at the et-R R-1 reactor. Vol. 2

International Nuclear Information System (INIS)

Naguib, K.; Habib, N.; Kilany, M.; Adib, M.; Wahba, M.

1996-01-01

The pulsed neutron polyenergetic thermal beam at ET-R R-1 is produced by a phased double-rotor facility. One of the rotors has two diametrically opposite curved slots, while the second is designed to operate as a rotating collimator, the dimensions of the phased rotating collimator are selected to match the curved slot rotor. The calculated collimator transmissions at different operating conditions are found to be in good agreement with the experimental ones. The optimum operating conditions of double-rotor facility are deduced. The calculations were carried out using a computer programme RCOL. The RCOL was designed in Fortran-77 to operate on PCs. 6 figs

Microsoft System Center 2012 R2 Operations Manager cookbook

CERN Document Server

Beaumont (MVP), Steve; Odika, Chiyo; Ryan, Robert

2015-01-01

If you are tasked with monitoring the IT infrastructure within your organization, this book demonstrates how System Center 2012 R2 Operations Manager offers a radical and exciting solution to modern administration.

42 CFR 412.507 - Limitation on charges to beneficiaries.

Science.gov (United States)

2010-10-01

... prospective payment system. If Medicare has paid the full LTC-DRG payment, that payment applies to the... SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Long-Term Care Hospitals § 412.507 Limitation on charges to beneficiaries. (a) Prohibited...

47 CFR 0.485 - Commercial radio operator examinations.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Commercial radio operator examinations. 0.485....485 Commercial radio operator examinations. Generally, written and telegraphy examinations for commercial radio operator licenses shall be conducted at locations and times specified by commercial operator...

31 CFR 593.412 - Release of any round log or timber product originating in Liberia from a bonded warehouse or...

Science.gov (United States)

2010-07-01

... product originating in Liberia from a bonded warehouse or foreign trade zone. 593.412 Section 593.412... Interpretations § 593.412 Release of any round log or timber product originating in Liberia from a bonded... from a bonded warehouse or foreign trade zone of any round log or timber product originating in Liberia...

33 CFR 334.412 - Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area. 334.412 Section 334.412 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA...

7 CFR 28.412 - Strict Middling Light Spotted Color.

Science.gov (United States)

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Light Spotted Color. 28.412 Section 28... Light Spotted Color. Strict Middling Light Spotted Color is color which in spot or color, or both, is between Strict Middling Color and Strict Middling Spotted Color. ...

Remedial investigation/feasibility study Work Plan and addenda for Operable Unit 4-12: Central Facilities Area Landfills II and III at the Idaho National Engineering Laboratory

Energy Technology Data Exchange (ETDEWEB)

Keck, K.N.; Stormberg, G.J.; Porro, I.; Sondrup, A.J.; McCormick, S.H.

1993-07-01

This document is divided into two main sections -- the Work Plan and the addenda. The Work Plan describes the regulatory history and physical setting of Operable Unit 4-12, previous sampling activities, and data. It also identifies a preliminary conceptual model, preliminary remedial action alternatives, and preliminary applicable or relevant and appropriate requirements. In addition, the Work Plan discusses data gaps and data quality objectives for proposed remedial investigation activities. Also included are tasks identified for the remedial investigation/feasibility study (RI/FS) and a schedule of RI/FS activities. The addenda include details of the proposed field activities (Field Sampling Plan), anticipated quality assurance activities (Quality Assurance Project Plan), policies and procedures to protect RI/FS workers and the environment during field investigations (Health and Safety Plan), and policies, procedures, and activities that the Department of Energy will use to involve the public in the decision-making process concerning CFA Landfills II and III RI/FS activities (Community Relations Plan).

Remedial investigation/feasibility study Work Plan and addenda for Operable Unit 4-12: Central Facilities Area Landfills II and III at the Idaho National Engineering Laboratory

International Nuclear Information System (INIS)

Keck, K.N.; Stormberg, G.J.; Porro, I.; Sondrup, A.J.; McCormick, S.H.

1993-07-01

This document is divided into two main sections -- the Work Plan and the addenda. The Work Plan describes the regulatory history and physical setting of Operable Unit 4-12, previous sampling activities, and data. It also identifies a preliminary conceptual model, preliminary remedial action alternatives, and preliminary applicable or relevant and appropriate requirements. In addition, the Work Plan discusses data gaps and data quality objectives for proposed remedial investigation activities. Also included are tasks identified for the remedial investigation/feasibility study (RI/FS) and a schedule of RI/FS activities. The addenda include details of the proposed field activities (Field Sampling Plan), anticipated quality assurance activities (Quality Assurance Project Plan), policies and procedures to protect RI/FS workers and the environment during field investigations (Health and Safety Plan), and policies, procedures, and activities that the Department of Energy will use to involve the public in the decision-making process concerning CFA Landfills II and III RI/FS activities (Community Relations Plan)

13 CFR 123.412 - What happens if SBA declines your business' pre-disaster mitigation loan request?

Science.gov (United States)

2010-01-01

...' loan request, SBA will notify your business in writing giving specific reasons for decline. If your... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What happens if SBA declines your business' pre-disaster mitigation loan request? 123.412 Section 123.412 Business Credit and Assistance...

25 CFR 170.412 - How is the tribal IRR long-range transportation plan developed and approved?

Science.gov (United States)

2010-04-01

...-range transportation plan developed and approved? (a) The tribal IRR long-range transportation plan is... 25 Indians 1 2010-04-01 2010-04-01 false How is the tribal IRR long-range transportation plan developed and approved? 170.412 Section 170.412 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR...

Two-host, two-vector basic reproduction ratio (R(0 for bluetongue.

Directory of Open Access Journals (Sweden)

Joanne Turner

Full Text Available Mathematical formulations for the basic reproduction ratio (R(0 exist for several vector-borne diseases. Generally, these are based on models of one-host, one-vector systems or two-host, one-vector systems. For many vector borne diseases, however, two or more vector species often co-occur and, therefore, there is a need for more complex formulations. Here we derive a two-host, two-vector formulation for the R(0 of bluetongue, a vector-borne infection of ruminants that can have serious economic consequences; since 1998 for example, it has led to the deaths of well over 1 million sheep in Europe alone. We illustrate our results by considering the situation in South Africa, where there are two major hosts (sheep, cattle and two vector species with differing ecologies and competencies as vectors, for which good data exist. We investigate the effects on R(0 of differences in vector abundance, vector competence and vector host preference between vector species. Our results indicate that R(0 can be underestimated if we assume that there is only one vector transmitting the infection (when there are in fact two or more and/or vector host preferences are overlooked (unless the preferred host is less beneficial or more abundant. The two-host, one-vector formula provides a good approximation when the level of cross-infection between vector species is very small. As this approaches the level of intraspecies infection, a combination of the two-host, one-vector R(0 for each vector species becomes a better estimate. Otherwise, particularly when the level of cross-infection is high, the two-host, two-vector formula is required for accurate estimation of R(0. Our results are equally relevant to Europe, where at least two vector species, which co-occur in parts of the south, have been implicated in the recent epizootic of bluetongue.

42 CFR 412.404 - Conditions for payment under the prospective payment system for inpatient hospital services of...

Science.gov (United States)

2010-10-01

... payment system for inpatient hospital services of psychiatric facilities. 412.404 Section 412.404 Public... PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Inpatient Hospital... must meet the conditions of this section to receive payment under the prospective payment system...

42 CFR 412.322 - Indirect medical education adjustment factor.

Science.gov (United States)

2010-10-01

... Payment System for Inpatient Hospital Capital Costs Basic Methodology for Determining the Federal Rate for Capital-Related Costs § 412.322 Indirect medical education adjustment factor. (a) Basic data. CMS.... The indirect teaching adjustment factor equals [e (raised to the power of .2822×the ratio of residents...

Data Qualification Report For: Thermodynamic Data File, DATA0.YMP.R0 For Geochemical Code, EQ3/6 

Energy Technology Data Exchange (ETDEWEB)

P.L. Cloke

2001-10-16

The objective of this work is to evaluate the adequacy of chemical thermodynamic data provided by Lawrence Livermore National Laboratory (LLNL) as DataO.ymp.ROA in response to an input request submitted under AP-3.14Q. This request specified that chemical thermodynamic data available in the file, Data0.com.R2, be updated, improved, and augmented for use in geochemical modeling used in Process Model Reports (PMRs) for Engineered Barrier Systems, Waste Form, Waste Package, Unsaturated Zone, and Near Field Environment, as well as for Performance Assessment. The data are qualified in the temperature range 0 to 100 C. Several Data Tracking Numbers (DTNs) associated with Analysis/Model Reports (AMR) addressing various aspects of the post-closure chemical behavior of the waste package and the Engineered Barrier System that rely on EQ316 outputs to which these data are used as input, are Principal Factor affecting. This qualification activity was accomplished in accordance with the AP-SIII.2Q using the Technical Assessment method. A development plan, TDP-EBS-MD-000044, was prepared in accordance with AP-2.13Q and approved by the Responsible Manager. In addition, a Process Control Evaluation was performed in accordance with AP-SV.1Q. The qualification method, selected in accordance with AP-SIII.2Q, was Technical Assessment. The rationale for this approach is that the data in File Data0.com.R2 are considered Handbook data and therefore do not themselves require qualification. Only changes to Data0.com.R2 required qualification. A new file has been produced which contains the database Data0.ymp.R0, which is recommended for qualification as a result of this action. Data0.ymp.R0 will supersede Data0.com.R2 for all Yucca Mountain Project (YMP) activities.

Recurrent SETBP1 mutations in atypical chronic myeloid leukemia

Science.gov (United States)

Piazza, Rocco; Valletta, Simona; Winkelmann, Nils; Redaelli, Sara; Spinelli, Roberta; Pirola, Alessandra; Antolini, Laura; Mologni, Luca; Donadoni, Carla; Papaemmanuil, Elli; Schnittger, Susanne; Kim, Dong-Wook; Boultwood, Jacqueline; Rossi, Fabio; Gaipa, Giuseppe; De Martini, Greta P; di Celle, Paola Francia; Jang, Hyun Gyung; Fantin, Valeria; Bignell, Graham R; Magistroni, Vera; Haferlach, Torsten; Pogliani, Enrico Maria; Campbell, Peter J; Chase, Andrew J; Tapper, William J; Cross, Nicholas C P; Gambacorti-Passerini, Carlo

2013-01-01

Atypical chronic myeloid leukemia (aCML) shares clinical and laboratory features with CML, but it lacks the BCR-ABL1 fusion. We performed exome sequencing of eight aCMLs and identified somatic alterations of SETBP1 (encoding a p.Gly870Ser alteration) in two cases. Targeted resequencing of 70 aCMLs, 574 diverse hematological malignancies and 344 cancer cell lines identified SETBP1 mutations in 24 cases, including 17 of 70 aCMLs (24.3%; 95% confidence interval (CI) = 16–35%). Most mutations (92%) were located between codons 858 and 871 and were identical to changes seen in individuals with Schinzel-Giedion syndrome. Individuals with mutations had higher white blood cell counts (P = 0.008) and worse prognosis (P = 0.01). The p.Gly870Ser alteration abrogated a site for ubiquitination, and cells exogenously expressing this mutant exhibited higher amounts of SETBP1 and SET protein, lower PP2A activity and higher proliferation rates relative to those expressing the wild-type protein. In summary, mutated SETBP1 represents a newly discovered oncogene present in aCML and closely related diseases. PMID:23222956

Clinical value and potential pathways of miR-183-5p in bladder cancer: A study based on miRNA-seq data and bioinformatics analysis.

Science.gov (United States)

Gao, Jia-Min; Huang, Lin-Zhen; Huang, Zhi-Guang; He, Rong-Quan

2018-04-01

The clinicopathological value and exploration of the potential molecular mechanism of microRNA-183-5p (miR-183-5p) have been investigated in various cancers; however, to the best of the author's knowledge, no similar research has been reported for bladder cancer. In the present study, it was revealed that the expression level of miR-183-5p was notably increased in bladder cancer tissues compared with adjacent non-cancerous tissues (P=0.001) and was markedly increased in the tissue samples of papillary, pathological T stage (T0-T2) and pathological stage (I-II) compared with tissue samples of their counterparts (P=0.05), according to data from The Cancer Genome Atlas. Receiver operating characteristic analysis revealed the robust diagnostic value of miR-183-5p for distinguishing bladder cancer from non-cancerous bladder tissues (area under curve=0.948; 95% confidence interval: 0.919-0.977). Amplification and deep deletion of miR-183-5p were indicated by cBioPortal, accounting for 1% (4/412) of bladder cancer cases. Data from YM500v3 demonstrated that compared with other cancers, bladder cancer exhibited high expression levels of miR-183-5p, and miR-183-5p expression in primary solid tumors was much higher compared with solid normal tissues. A meta-analysis indicated that miR-183-5p was more highly expressed in bladder cancer samples compared with normal counterparts. A total of 88 potential target genes of miR-183-5p were identified, 13 of which were discerned as hub genes by protein-protein interaction. The epithelial-to-mesenchymal transition pathway was the most significantly enriched pathway by FunRich (P=0.0001). In summary, miR-183-5p may participate in the tumorigenesis and development of bladder cancer via certain signaling pathways, particularly the epithelial-to-mesenchymal transition pathway. However, the exact molecular mechanism of miR-183-5p in bladder cancer must be validated by in vitro and in vivo experiments.

77 FR 26321 - Reed College, Reed Research Nuclear Reactor, Renewed Facility Operating License No. R-112

Science.gov (United States)

2012-05-03

... Nuclear Reactor, Renewed Facility Operating License No. R-112 AGENCY: Nuclear Regulatory Commission... Commission (NRC or the Commission) has issued renewed Facility Operating License No. R- 112, held by Reed... License No. R-112 will expire 20 years from its date of issuance. The renewed facility operating license...

77 FR 68155 - The Armed Forces Radiobiology Research Institute TRIGA Reactor: Facility Operating License No. R-84

Science.gov (United States)

2012-11-15

... Research Institute TRIGA Reactor: Facility Operating License No. R-84 AGENCY: Nuclear Regulatory Commission... considering an application for the renewal of Facility Operating License No. R-84 (Application), which... the renewal of Facility Operating License No. R-84, which currently authorizes the licensee to operate...

20 CFR 404.412 - After my benefits are reduced for age when and how will adjustments to that reduction be made?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false After my benefits are reduced for age when and how will adjustments to that reduction be made? 404.412 Section 404.412 Employees' Benefits SOCIAL...; and Nonpayments of Benefits § 404.412 After my benefits are reduced for age when and how will...

Satellite remote sensing of a low-salinity water plume in the East China Sea

Directory of Open Access Journals (Sweden)

Y. H. Ahn

2008-07-01

Full Text Available With the aim to map and monitor a low-salinity water (LSW plume in the East China Sea (ECS, we developed more robust and proper regional algorithms from large in-situ measurements of apparent and inherent optical properties (i.e. remote sensing reflectance, R_rs, and absorption coefficient of coloured dissolved organic matter, a_CDOM determined in ECS and neighboring waters. Using the above data sets, we derived the following relationships between visible R_rs and absorption by CDOM, i.e. R_rs (412/R_rs (555 vs. a_CDOM (400 (m⁻¹ and a_CDOM (412 (m⁻¹ with a correlation coefficient R² 0.67 greater than those noted for R_rs (443/R_rs (555 and R_rs (490/R_rs (555 vs. a_CDOM (400 (m⁻¹ and a_CDOM (412 (m⁻¹. Determination of a_CDOM (m⁻¹ at 400 nm and 412 nm is particularly necessary to describe its absorption as a function of wavelength λ using a single exponential model in which the spectral slope S as a proxy for CDOM composition is estimated by the ratio of a_CDOM at 412 nm and 400 nm and the reference is explained simply by a_CDOM at 412 nm. In order to derive salinity from the absorption coefficient of CDOM, in-situ measurements of salinity made in a wide range of water types from dense oceanic to light estuarine/coastal systems were used along with in-situ measurements of a_CDOM at 400 nm, 412 nm, 443 nm and 490 nm. The CDOM absorption at 400 nm was better inversely correlated (R²=0.86 with salinity than at 412 nm, 443 nm and 490 nm (R²=0.85–0.66, and this correlation corresponded best with an exponential (R²=0

Electronic and magnetic properties of R0.5A0.5MnO3 compounds (R=Gd, Dy, Ho, Er; A=Sr, Ca)

International Nuclear Information System (INIS)

Terai, T.; Sasaki, T.; Kakeshita, T.; Fukuda, T.; Saburi, T.; Kitagawa, H.; Kindo, K.; Honda, M.

2000-01-01

Electronic and magnetic properties of the perovskitelike compounds of R 0.5 A 0.5 MnO 3 (R=Gd, Dy, Ho, Er; A=Sr, Ca) have been studied by measuring lattice parameter, electrical resistivity, magnetic susceptibility, and magnetization. All the Sr-doped compounds show a transition from a paramagnetic insulator to a spin-glass-like insulator at T g , even though the manganite La 0.5 Ca 0.5 MnO 3 , with nearly the same tolerance factor t, have been shown by others, to have different transitions. On the other hand, all the Ca-doped compounds show a charge-ordering transition at T CO and show a transition from a paramagnetic insulator to a canted antiferromagnetic insulator and/or a spin-glass-like insulator at T CA below T CO . These transition temperatures decrease with decreasing t. In the compound of Gd 0.5 Ca 0.5 MnO 3 , the collapse of the charge ordering has been observed under a pulsed high magnetic field of 45 T at 4.2 K. On the other hand, in the compound of Gd 0.5 Sr 0.5 MnO 3 , the magnetization process depends on the strength of magnetic field. These electronic and magnetic properties depend not only on the tolerance factor but also the variance (second moment) of the A-site ion radii distribution

Preliminary crystallographic analysis of the RNA-binding domain of HuR and its poly(U)-binding properties

International Nuclear Information System (INIS)

Wang, Hong; Li, Heng; Shi, Hui; Liu, Yang; Liu, Huihui; Zhao, Hui; Niu, Liwen; Teng, Maikun; Li, Xu

2011-01-01

Here, the recombinant ARE-binding region of HuR (residues 18–186) was crystallized in space group P2 1 2 1 2, with unit-cell parameters a = 41.2, b = 133.1, c = 31.4 Å. Human antigen R (HuR), a ubiquitously expressed member of the Hu protein family, is an important post-transcriptional regulator which has three RNA-recognition motif (RRM) domains. The two tandem N-terminal RRM domains can selectively bind to the AU-rich element (ARE), while the third one interacts with the poly(A) tail and other proteins. Here, the recombinant ARE-binding region of HuR (residues 18–186) was crystallized in space group P2 1 2 1 2, with unit-cell parameters a = 41.2, b = 133.1, c = 31.4 Å. X-ray diffraction data were collected to a resolution of 2.8 Å. Mutagenesis analysis and SPR assays revealed its poly(U)-binding properties

SAFT 4{1/2} inch nickel hydrogen battery cells

Energy Technology Data Exchange (ETDEWEB)

Duquesne, D.; Lacout, B.; Sennet, A. [SAFT Advanced Batteries, Poitiers (France)

1995-12-31

SAFT Advanced Batteries has now produced over 400 high capacity 4{1/2} inch Nickel Hydrogen Battery Cells for flight programs. The 4.5 inch diameter, rabbit-ear cell design is designed to provide the anticipated energy required at the lowest practical weight. SAFT has incorporated into the design of the dry-powder nickel electrode, truly hermetic ceramic to metal seals, qualified terminal feedthroughs, high reliability mechanical design, composite pure platinum negative electrode, and zircar separator, plus more than 25 years experience in aerospace nickel cell technology, resulting in a 4{1/2} inch configuration with the 3{1/2} inch cell design carryover heritage. General performance requirements for GEO missions that SAFT cells meet are 15 years in orbit lifetime, 80% DOD, low mass to energy ratios, and flexible capacity by modifying number of electrodes in the stack. This design is qualified for geostationary orbits based on SAFT`s 3{1/2} inch qualification heritage, design verification, and cycling performed by customer Space Systems/LORAL in support of the INTELSAT VIIA and N-STAR flight programs.

Modifications in the operational conditions of the IEA-R1 reactor under continuous 48 hours operation

International Nuclear Information System (INIS)

Moreira, Joao Manoel Losada; Frajndlich, Roberto

1995-01-01

This work shows the required changes in the IEA-R1 reactor for operation at 2 Mw, 48 hours continuously. The principal technical change regards the operating conditions of the reactor, namely, the required excess reactivity which now will amount to 4800 pcm in order to compensate the Xe poisoning at equilibrium at 2 Mw. (author). 6 refs, 1 fig, 1 tab

37 CFR 1.412 - The United States Receiving Office.

Science.gov (United States)

2010-07-01

... Information § 1.412 The United States Receiving Office. (a) The United States Patent and Trademark Office is a Receiving Office only for applicants who are residents or nationals of the United States of America. (b) The... “United States Receiving Office” or by the abbreviation “RO/US.” (c) The major functions of the Receiving...

Safety management of a complex R&D ground operating system

Science.gov (United States)

Connors, J.; Mauer, R. A.

1975-01-01

Report discusses safety program implementation for large R&D operating system. Analytical techniques are defined and suggested as tools for identifying potential hazards and determining means to effectively control or eliminate hazards.

Wiener-Hopf operators on spaces of functions on R+ with values in a Hilbert space

OpenAIRE

Petkova, Violeta

2006-01-01

A Wiener-Hopf operator on a Banach space of functions on R+ is a bounded operator T such that P^+S_{-a}TS_a=T, for every positive a, where S_a is the operator of translation by a. We obtain a representation theorem for the Wiener-Hopf operators on a large class of functions on R+ with values in a separable Hilbert space.

FAA perspectives on historical wake turbulence R&D to recent operational implementations

Science.gov (United States)

2017-06-03

A major intent of this presentation is to delineate why the many years of wake turbulence R&D are finally yielding beneficial operational implementations. It will highlight lessons learned from past R&D and going forward for NextGen and beyond.

Optical band gap and Raman spectra in AxB0.2-x(TeO2)0.8 glasses

Czech Academy of Sciences Publication Activity Database

Ožďanová, J.; Tichá, H.; Tichý, Ladislav

2010-01-01

Roč. 12, č. 5 (2010), s. 1024-1029 ISSN 1454-4164 Institutional research plan: CEZ:AV0Z40500505 Keywords : telluride glasses * optical band gap * Raman scattering Subject RIV: CA - Inorganic Chemistry Impact factor: 0.412, year: 2010 http://joam.inoe.ro/index.php?option=magazine&op=view&idu=2453&catid=50

The R{sup ∗}-operation for Feynman graphs with generic numerators

Energy Technology Data Exchange (ETDEWEB)

Herzog, Franz [Nikhef Theory Group,Science Park 105, 1098 XG Amsterdam (Netherlands); Ruijl, Ben [Nikhef Theory Group,Science Park 105, 1098 XG Amsterdam (Netherlands); Leiden University,Niels Bohrweg 1, 2333 CA Leiden (Netherlands)

2017-05-08

The R{sup ∗}-operation by Chetyrkin, Tkachov, and Smirnov is a generalisation of the BPHZ R-operation, which subtracts both ultraviolet and infrared divergences of euclidean Feynman graphs with non-exceptional external momenta. It can be used to compute the divergent parts of such Feynman graphs from products of simpler Feynman graphs of lower loops. In this paper we extend the R{sup ∗}-operation to Feynman graphs with arbitrary numerators, including tensors. We also provide a novel way of defining infrared counterterms which closely resembles the definition of its ultraviolet counterpart. We further express both infrared and ultraviolet counterterms in terms of scaleless vacuum graphs with a logarithmic degree of divergence. By exploiting symmetries, integrand and integral relations, which the counterterms of scaleless vacuum graphs satisfy, we can vastly reduce their number and complexity. A FORM implementation of this method was used to compute the five loop beta function in QCD for a general gauge group. To illustrate the procedure, we compute the poles in the dimensional regulator of all top-level propagator graphs at five loops in four dimensional ϕ{sup 3} theory.

76 FR 62868 - Washington State University; Notice of Issuance of Renewed Facility Operating License No. R-76

Science.gov (United States)

2011-10-11

...; Notice of Issuance of Renewed Facility Operating License No. R-76 AGENCY: Nuclear Regulatory Commission. ACTION: Notice of issuance of renewed facility operating license No. R- 76. ADDRESSES: You can access.... Nuclear Regulatory Commission (NRC, the Commission) has issued renewed Facility Operating License No. R-76...

Efficient Bulk Operations on Dynamic R-Trees

DEFF Research Database (Denmark)

Arge, Lars Allan; Hinrichs, Klaus; Vahrenhold, Jan

2002-01-01

In recent years there has been an upsurge of interest in spatial databases. A major issue is how to manipulate efficiently massive amounts of spatial data stored on disk in multidimensional spatial indexes (data structures). Construction of spatial indexes (bulk loading ) has been studied...... intensively in the database community. The continuous arrival of massive amounts of new data makes it important to update existing indexes (bulk updating ) efficiently. In this paper we present a simple, yet efficient, technique for performing bulk update and query operations on multidimensional indexes. We...... present our technique in terms of the so-called R-tree and its variants, as they have emerged as practically efficient indexing methods for spatial data. Our method uses ideas from the buffer tree lazy buffering technique and fully utilizes the available internal memory and the page size of the operating...

Beyond R0 Maximisation: On Pathogen Evolution and Environmental Dimensions.

Science.gov (United States)

Lion, Sébastien; Metz, Johan A J

2018-06-01

A widespread tenet is that evolution of pathogens maximises their basic reproduction ratio, R 0 . The breakdown of this principle is typically discussed as exception. Here, we argue that a radically different stance is needed, based on evolutionarily stable strategy (ESS) arguments that take account of the 'dimension of the environmental feedback loop'. The R 0 maximisation paradigm requires this feedback loop to be one-dimensional, which notably excludes pathogen diversification. By contrast, almost all realistic ecological ingredients of host-pathogen interactions (density-dependent mortality, multiple infections, limited cross-immunity, multiple transmission routes, host heterogeneity, and spatial structure) will lead to multidimensional feedbacks. Copyright © 2018 Elsevier Ltd. All rights reserved.

Isolation and characterization of 5S rDNA sequences in catfishes genome (Heptapteridae and Pseudopimelodidae): perspectives for rDNA studies in fish by C0t method.

Science.gov (United States)

Gouveia, Juceli Gonzalez; Wolf, Ivan Rodrigo; de Moraes-Manécolo, Vivian Patrícia Oliveira; Bardella, Vanessa Belline; Ferracin, Lara Munique; Giuliano-Caetano, Lucia; da Rosa, Renata; Dias, Ana Lúcia

2016-12-01

Sequences of 5S ribosomal RNA (rRNA) are extensively used in fish cytogenomic studies, once they have a flexible organization at the chromosomal level, showing inter- and intra-specific variation in number and position in karyotypes. Sequences from the genome of Imparfinis schubarti (Heptapteridae) were isolated, aiming to understand the organization of 5S rDNA families in the fish genome. The isolation of 5S rDNA from the genome of I. schubarti was carried out by reassociation kinetics (C 0 t) and PCR amplification. The obtained sequences were cloned for the construction of a micro-library. The obtained clones were sequenced and hybridized in I. schubarti and Microglanis cottoides (Pseudopimelodidae) for chromosome mapping. An analysis of the sequence alignments with other fish groups was accomplished. Both methods were effective when using 5S rDNA for hybridization in I. schubarti genome. However, the C 0 t method enabled the use of a complete 5S rRNA gene, which was also successful in the hybridization of M. cottoides. Nevertheless, this gene was obtained only partially by PCR. The hybridization results and sequence analyses showed that intact 5S regions are more appropriate for the probe operation, due to conserved structure and motifs. This study contributes to a better understanding of the organization of multigene families in catfish's genomes.

42 CFR 412.525 - Adjustments to the Federal prospective payment.

Science.gov (United States)

2010-10-01

... HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES Prospective Payment System for Long-Term Care Hospitals § 412.525 Adjustments to the Federal prospective payment. (a... its estimated costs for a patient exceed the adjusted LTC-MS-DRG payment plus a fixed-loss amount. For...

The combinatorial PP1-binding consensus Motif (R/Kx( (0,1V/IxFxx(R/Kx(R/K is a new apoptotic signature.

Directory of Open Access Journals (Sweden)

Angélique N Godet

Full Text Available BACKGROUND: Previous studies established that PP1 is a target for Bcl-2 proteins and an important regulator of apoptosis. The two distinct functional PP1 consensus docking motifs, R/Kx((0,1V/IxF and FxxR/KxR/K, involved in PP1 binding and cell death were previously characterized in the BH1 and BH3 domains of some Bcl-2 proteins. PRINCIPAL FINDINGS: In this study, we demonstrate that DPT-AIF(1, a peptide containing the AIF(562-571 sequence located in a c-terminal domain of AIF, is a new PP1 interacting and cell penetrating molecule. We also showed that DPT-AIF(1 provoked apoptosis in several human cell lines. Furthermore, DPT-APAF(1 a bi-partite cell penetrating peptide containing APAF-1(122-131, a non penetrating sequence from APAF-1 protein, linked to our previously described DPT-sh1 peptide shuttle, is also a PP1-interacting death molecule. Both AIF(562-571 and APAF-1(122-131 sequences contain a common R/Kx((0,1V/IxFxxR/KxR/K motif, shared by several proteins involved in control of cell survival pathways. This motif combines the two distinct PP1c consensus docking motifs initially identified in some Bcl-2 proteins. Interestingly DPT-AIF(2 and DPT-APAF(2 that carry a F to A mutation within this combinatorial motif, no longer exhibited any PP1c binding or apoptotic effects. Moreover the F to A mutation in DPT-AIF(2 also suppressed cell penetration. CONCLUSION: These results indicate that the combinatorial PP1c docking motif R/Kx((0,1V/IxFxxR/KxR/K, deduced from AIF(562-571 and APAF-1(122-131 sequences, is a new PP1c-dependent Apoptotic Signature. This motif is also a new tool for drug design that could be used to characterize potential anti-tumour molecules.

On the structure and optical band gap in some (PbO)x(BaO)0.3-x(ZnO)0.1(TeO2)0.6 glasses

Czech Academy of Sciences Publication Activity Database

Tichá, H.; Tichý, Ladislav

2015-01-01

Roč. 9, 7-8 (2015), s. 951-955 ISSN 1842-6573 Institutional support: RVO:61389013 Keywords : optical properties * oxide glasses * Raman spectroscopy Subject RIV: CA - Inorganic Chemistry Impact factor: 0.412, year: 2015 http://oam-rc.inoe.ro/index.php?option=magazine&op=view&idu=2643&catid=91

The many guises of R0 (a didactic note)

NARCIS (Netherlands)

Cushing, J. M.; Diekmann, Odo

2016-01-01

The basic reproduction number R0 is, by definition, the expected life time number of offspring of a newborn individual. An operationalization entails a specification of what events are considered as “reproduction” and what events are considered as “transitions from one individual-state to another”.

Parenting clinically anxious versus healthy control children aged 4-12 years

NARCIS (Netherlands)

van der Sluis, C.M.; van Steensel, F.J.A.; Bögels, S.M.

2015-01-01

This study investigated whether parenting behaviors differed between parents of 68 clinically anxious children and 106 healthy control children aged 4-12 years. The effects of parent gender, child gender and child age on parenting were explored. Mothers and fathers completed a questionnaire to

Search for r-parity violating supersymmetry in multilepton final states with the D0 detector

Energy Technology Data Exchange (ETDEWEB)

Kaefer, Daniela [RWTH Aachen Univ. (Germany)

2006-10-27

Results obtained from a search for the trilepton signature μμℓ (with ℓ = e, or μ) are combined with two complementary searches for the trilepton signatures eeℓ and eer and interpreted in the framework of R-parity violating Supersymmetry. Pairwise, R-parity conserving production of the supersymmetric particles is assumed, followed by R-parity violating decays via an LL$\\bar{E}$-operator with one dominant coupling λ₁₂₂. An LL$\\bar{E}$-operator couples two weak isospin doublet and one singlet (s)lepton fields and thus violates lepton number conservation. The data, collected with the D0 detector at the Fermilab proton-antiproton collider Tevatron, corresponds to an integrated luminosity of ∫ L dt = 360 ± 23 pb^-1. No evident is observed, while 0.41 ± 0.11(stat) ± 0.07(sys) events are expected from Standard Model processes. The resulting 95% confidence level cross section limits on new physics producing a μμℓ signature in the detector are of the order of 0.020 to 0.136 pb. They are interpreted in two different supersymmetry scenarios: the mSUGRA and the MSSM model. The corresponding lower limits on the masses of the lightest neutralino ($\\tilde{X}$$0\\atop{1}$) and the lightest chargino ($\\tilde{X}$$±\\atop{1}$ in case of the mSUGRA model are found to be in the range of: mSUGRA, μ > 0: M($\\tilde{X}$$0\\atop{1}$) ~> 115-128 GeV and M($\\tilde{X}$$±\\atop{1}$) ~> 215-241 GeV; mSUGRA, μ < 0: ($\\tilde{X}$$0\\atop{1}$) ~> 101-114 GeV and M($\\tilde{X}$$±\\atop{1}$) ~> 194-230 GeV, depending on the actual values of the model parameters: m₀, m_1/2, A₀, tanβ, and μ. The first and second parameters provide the boundary conditions for the masses of the supersymmetric spin-0 and spin-1/2 particles, respectively, while A₀ gives the universal value for the trilinear couplings at the GUT scale. The parameter tan β denotes the ratio of the vacuum expectation values of the two Higgs fields

Range of the radiation monitor for the rigid vent of primary containment during normal and emergency operation for a BWR-5 in Laguna Verde; Rango del monitor de radiacion para el venteo rigido de la contencion primaria durante operacion normal y emergencia para un reactor BWR-5 en Laguna Verde

Energy Technology Data Exchange (ETDEWEB)

Tijerina S, F.; Pozos S, A. M.; Cabrera U, S.; Mata A, J. A.; Sandoval V, S.; Ovando C, R.; Vargas A, A.; Gallardo R, I.; Cruz G, M.; Amador C, C., E-mail: francisco.tijerina@cfe.gob.mx [Comision Federal de Electricidad, Central Nucleoelectrica Laguna Verde, Subgerencia de Ingenieria, Km 44.5 Carretera Cardel-Nautla, 91476 Laguna Verde, Alto Lucero, Veracruz (Mexico)

2014-10-15

The earthquake followed by a tsunami, happened in March, 2011 in the coasts of oriental Japan, caused damages in the nuclear power plants 1 at 4 of Fukushima Daiichi leading to damage of the fuel in three of the reactors and to the radiation liberation to the exterior. As consequence of those events, the regulations requires that the power plants with Primary Containment type Mark I and II evaluate to have a system of rigid vent with a monitoring equipment of radiation effluents. The present work covers the rigid vent of diameter 12 of the Primary Containment, type Mark-II, of nuclear power plant of Laguna Verde in conditions of severe accident and normal operation, low regime of Extended Power Up rate (EPU - 2317 MWt), using the codes MAAP3B, MICROSHILED 5.05 and the Bardach Black Boxes methodology. As a result the measurement range of the radiation monitor that is required for monitoring the gassy liberation to the atmosphere was determined. The conclusion is that the superior limit of the range of the radiation meter during a Severe Accident is of 8.55 E + 05 R/h (8.55 E + 08 m R/h) and the superior limit in normal operation of 1.412 E-11 at 2.540 E-7 R/h (1.412 E-14 at 2.540 E-10 m R/h). (Author)

Industrie 4.0-Anwendungen für die Supply Chain

OpenAIRE

Hofmann, Erik; Oettmeier, Katrin

2017-01-01

Industrie 4.0 bedingt eine Vielzahl an Technologien, welche die digitale Vernetzung von Objekten ermöglichen. Im Folgenden wird die derzeitige und künftige Verwendung von Industrie 4.0-Technologien und -Lösungen bei Schweizer Unternehmen analysiert. Grundlage hierfür bilden die Ergebnisse einer grosszahligen Erhebung im Rahmen der Logistikmarktstudie Schweiz, Band 2017.

Recent theoretical results for 0νββ-decay including R0νECEC and 0νββM

Energy Technology Data Exchange (ETDEWEB)

Kotila, J., E-mail: jenni.kotila@yale.edu [Department of Physics, University of Jyväskylä, B.O. Box 35, FIN-40014, Jyväskylä (Finland); Center for Theoretical Physics, Sloane Physics Laboratory, Yale University, New Haven, Connecticut 06520-8120 (United States); Barea, J. [Departamento de Física, Universidad de Concepción, Casilla 160-C, Concepción 4070386 (Chile); Iachello, F. [Center for Theoretical Physics, Sloane Physics Laboratory, Yale University, New Haven, Connecticut 06520-8120 (United States)

2015-10-28

The most recent (2015) results for 0νββ nuclear matrix elements in the interacting boson model (IBM-2) with light and heavy neutrino exchange, including R0νECEC, are given for all nuclei of interest from {sup 48}Ca to {sup 238}U. Predictions for half-lives and limits for average neutrino mass are also made. Possible additional scenarios, such as Majoron emission, is also discussed.

Phase transition and conduction mechanism in Pb{sub 2}Na{sub 0.8}R{sub 0.2}Nb{sub 4.8}Fe{sub 0.2}O{sub 15} material (R=rare earth)

Energy Technology Data Exchange (ETDEWEB)

Bouziane, M. [Laboratoire de Chimie du Solide Appliquée, Faculté des Sciences, Université Mohammed V-Agdal, Avenue Ibn Batouta, BP 1014 Rabat (Morocco); Taibi, M., E-mail: taibiens@yahoo.fr [Laboratoire de Physico-Chimie des Matériaux (LAF 502), Ecole Normale Supérieure, Université Mohammed V-Agdal, BP 5118 Rabat (Morocco); Boukhari, A. [Laboratoire de Chimie du Solide Appliquée, Faculté des Sciences, Université Mohammed V-Agdal, Avenue Ibn Batouta, BP 1014 Rabat (Morocco)

2013-11-15

Electrical properties of Pb{sub 2}Na{sub 0.8}Eu{sub 0.2}Nb{sub 4.8}Fe{sub 0.2}O{sub 15} tungsten bronze compound were investigated. Ferroelectric phase transition of diffuse type is observed at 395 °C. Conductivity study as a function of temperature (RT-600 °C) and at three different frequencies (10, 100 and 1000 kHz) suggests the existence of dominant ionic conduction. The rise of ac conductivity on increasing temperature supports the NTCR (negative temperature coefficient of resistance) behaviour of the material. The activation energies have been evaluated from ac conductivity using Arrhenius equation and discussed. Different conduction mechanisms were identified. For comparison, the conducting properties of Pb{sub 2}Na{sub 0.8}R{sub 0.2}Nb{sub 4.8}Fe{sub 0.2}O{sub 15} (R=Dy, Nd, La) were also investigated. - Graphical abstract: Thermal evolution of lnσ{sub ac} of Pb{sub 2}Na{sub 0.8}Eu{sub 0.2}Nb{sub 4.8}Fe{sub 0.2}O{sub 15} at selected frequencies. Display Omitted - Highlights: • We found that TB compounds exhibit a diffuse type of first- order transition. • A negative temperature coefficient of resistance (NTCR) behaviour is observed. • Three conduction mechanisms were identified: n-and/or p-type at low temperatures. • The conduction mechanism in the studied compounds is very complex.

The classic metaphyseal lesion and traumatic injury

International Nuclear Information System (INIS)

Thackeray, Jonathan D.; Wannemacher, Jacob; Adler, Brent H.; Lindberg, Daniel M.

2016-01-01

It is widely accepted that the classic metaphyseal lesion (CML) is a traumatic lesion, strongly associated with abuse in infants. Nevertheless, various non-traumatic origins for CMLs continue to be suggested in medical and legal settings. No studies to date systematically describe the association of CMLs with other traumatic injuries. The primary objective of this study is to examine the association of CMLs with other traumatic injuries in a large data set of children evaluated for physical abuse. This was a retrospectively planned secondary analysis of data from a prospective, observational study of children <120 months of age who underwent evaluation by a child abuse physician. For this secondary analysis, we identified all children ≤12 months of age with an identified CML and determined the number and type of additional injuries identified. Descriptive analysis was used to report frequency of additional traumatic injuries. Among 2,890 subjects, 119 (4.1%) were identified as having a CML. Of these, 100 (84.0%) had at least one additional (non-CML) fracture. Thirty-three (27.7%) had traumatic brain injury. Nearly half (43.7%) of children had cutaneous injuries. Oropharyngeal injuries were found in 12 (10.1%) children. Abdominal/thoracic injuries were also found in 12 (10.1%) children. In all, 95.8% of children with a CML had at least one additional injury; one in four children had three or more categories of injury. CMLs identified in young children are strongly associated with traumatic injuries. Identification of a CML in a young child should prompt a thorough evaluation for physical abuse. (orig.)

Geometric extension through Schwarzschild r = 0

International Nuclear Information System (INIS)

Lynden-Bell, D.; Katz, J.; Hebrew Univ., Jerusalem

1990-01-01

Singularities in space-time are not necessarily cancers in the manifold but can herald interesting topological change in the space-time at places where there are several different tangent Minkowski spaces. Most discussions of gravitational collapse cease when space-time becomes singular. In the 'hour-glass' universe we have an example where the singularity develops in empty space; here we give a geometrical extension through the singularity in which geodesics that enter it emerge into a new space. The result extends Schwarzschild space and is periodic in 'extended' Penrose coordinates. There is a topological singularity but no mass at r = 0. The extension is mildly nonanalytic but unique. It is based on the concept that time does not stop and that empty space-times which develop singularities must still have zero Ricci tensors even where the Riemann tensor becomes infinite. (author)

Neuro-optimal operation of a variable air volume HVAC and R system

International Nuclear Information System (INIS)

Ning Min; Zaheeruddin, M.

2010-01-01

Low operational efficiency especially under partial load conditions and poor control are some reasons for high energy consumption of heating, ventilation, air conditioning and refrigeration (HVAC and R) systems. To improve energy efficiency, HVAC and R systems should be efficiently operated to maintain a desired indoor environment under dynamic ambient and indoor conditions. This study proposes a neural network based optimal supervisory operation strategy to find the optimal set points for chilled water supply temperature, discharge air temperature and VAV system fan static pressure such that the indoor environment is maintained with the least chiller and fan energy consumption. To achieve this objective, a dynamic system model is developed first to simulate the system behavior under different control schemes and operating conditions. A multi-layer feed forward neural network is constructed and trained in unsupervised mode to minimize the cost function which is comprised of overall energy cost and penalty cost when one or more constraints are violated. After training, the network is implemented as a supervisory controller to compute the optimal settings for the system. Simulation results show that compared to the conventional night reset operation scheme, the optimal operation scheme saves around 10% energy under full load condition and 19% energy under partial load conditions.

Topotactic reduction and reoxidation of hexagonal RCu0.5Ti0.5O3 (R = Y, Eu-Lu) Phases

International Nuclear Information System (INIS)

Jiang, Peng; Berthelot, Romain; Li, Jun; Sleight, A.W.; Subramanian, M.A.

2013-01-01

Highlights: ► Topotactic reduction of hexagonal RCu 0.5 Ti 0.5 O 3 phases is performed. ► TGA and magnetism indicate a formula of RCu 0.5 Ti 0.5 O 2.78 for the reduced phase. ► Topotactic reoxidation occurs on heating these phases to 400 °C in air. - Abstract: Hexagonal AMO 2 and AMO 3 phases have the same basic structure, and intermediate compositions for this structure have been prepared by topotactic oxidation of AMO 2 phases such as RCuO 2 , where R is a trivalent rare earth cation. We now find that such intermediate phases can also be prepared by topotactic reduction of hexagonal RCu 0.5 Ti 0.5 O 3 (R = Y, Tb-Lu) phases. Our TGA and magnetic susceptibility studies indicate a formula of RCu 0.5 Ti 0.5 O 2.78 for these reduced phases. Topotactic reoxidation occurs on heating these phases to 400 °C in air

77 FR 30588 - R.J. Corman Railroad Company/Pennsylvania Lines Inc.-Construction and Operation Exemption-In...

Science.gov (United States)

2012-05-23

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35116] R.J. Corman Railroad Company/Pennsylvania Lines Inc.-- Construction and Operation Exemption--In Clearfield County, PA.... 10901 for R.J. Corman Railroad Company/Pennsylvania Lines Inc. (RJCP) to construct and operate 10.8...

Satellite remote sensing of a low-salinity water plume in the East China Sea

Directory of Open Access Journals (Sweden)

Y. H. Ahn

2008-07-01

Full Text Available With the aim to map and monitor a low-salinity water (LSW plume in the East China Sea (ECS, we developed more robust and proper regional algorithms from large in-situ measurements of apparent and inherent optical properties (i.e. remote sensing reflectance, Rrs, and absorption coefficient of coloured dissolved organic matter, aCDOM determined in ECS and neighboring waters. Using the above data sets, we derived the following relationships between visible Rrs and absorption by CDOM, i.e. Rrs (412/Rrs (555 vs. aCDOM (400 (m−1 and aCDOM (412 (m−1 with a correlation coefficient R2 0.67 greater than those noted for Rrs (443/Rrs (555 and Rrs (490/Rrs (555 vs. aCDOM (400 (m−1 and aCDOM (412 (m−1. Determination of aCDOM (m−1 at 400 nm and 412 nm is particularly necessary to describe its absorption as a function of wavelength λ using a single exponential model in which the spectral slope S as a proxy for CDOM composition is estimated by the ratio of aCDOM at 412 nm and 400 nm and the reference is explained simply by aCDOM at 412 nm. In order to derive salinity from the absorption coefficient of CDOM, in-situ measurements of salinity made in a wide range of water types from dense oceanic to light estuarine/coastal systems were used along with in-situ measurements of aCDOM at 400 nm, 412 nm, 443 nm and 490 nm. The CDOM absorption at 400 nm was better inversely correlated (R2=0.86 with salinity than at 412 nm, 443 nm and 490 nm (R2=0.85–0.66, and this correlation corresponded best with an exponential (R2=0.98 rather than a linear function of salinity measured in a variety of water types from this and other regions. Validation against a discrete in-situ data set showed that empirical algorithms derived from the above relationships could be successfully applied to satellite data over the range of water types for which they have been developed. Thus, we applied these algorithms to a series of SeaWiFS images for the derivation of CDOM and salinity

Asymptotic Distribution of Eigenvalues for a Class of Second-Order Elliptic Operators with Irregular Coefficients in R{sup d}

Energy Technology Data Exchange (ETDEWEB)

Zielinski, Lech [Universite du Littoral, LMPA (France)], E-mail: lech.zielinski@lmpa.univ-littoral.fr

2002-06-15

Let A=A{sub 0}+v(x) where A{sub 0} is a second-order uniformly elliptic self-adjoint operator in R{sup d} and v is a real valued polynomially growing potential. Assuming that v and the coefficients of A{sub 0} are Hoelder continuous, we study the asymptotic behaviour of the counting function N(A,{lambda}) ({lambda}{sup {yields}}{infinity}) with the remainder estimates depending on the regularity hypotheses. Our strongest regularity hypotheses involve Lipschitz continuity and give the remainder estimate N(A,{lambda})O({l_brace}{lambda}{r_brace}{sup -{mu}}), where {mu} may take an arbitrary value strictly smaller than the best possible value known in the smooth case. In particular, our results are obtained without any hypothesis on critical points of the potential.

29 CFR 2580.412-35 - Disqualification of agents, brokers and sureties.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Disqualification of agents, brokers and sureties. 2580.412...-35 Disqualification of agents, brokers and sureties. Since 13(c) is to be construed as disqualifying any agent, broker, surety or other company from having a bond placed through or with it, if the plan...

On signal design by the R sub 0 criterion for non-white Gaussian noise channels

Science.gov (United States)

Bordelon, D. L.

1976-01-01

The use of the R sub 0 criterion for modulation system design is investigated for channels with non-white Gaussian noise. A signal space representation of the waveform channel is developed, and the cut-off rate R sub 0 for vector channels with additive nonwhite Gaussian noise and unquantized demodulation is derived. When the signal unput to the channel is a continuous random vector, maximization of R sub 0 with constrained average signal energy leads to a water-filling interpretation of optimal energy distribution in signal space. The necessary condition for a finite signal set to maximize R sub 0 with constrained energy and an equally likely probability assignment of signal vectors is presented, and an algorithm is outlined for numerically computing the optimum signal set. A necessary condition on a constrained energy, finite signal set is found which maximizes a Taylor series approximation of R sub 0. This signal set is compared with the finite signal set which has the water-filling average energy distribution.

Safety management of a complex R and D ground operating system

Science.gov (United States)

Connors, J. F.; Maurer, R. A.

1975-01-01

A perspective on safety program management was developed for a complex R&D operating system, such as the NASA-Lewis Research Center. Using a systems approach, hazardous operations are subjected to third-party reviews by designated-area safety committees and are maintained under safety permit controls. To insure personnel alertness, emergency containment forces and employees are trained in dry-run emergency simulation exercises. The keys to real safety effectiveness are top management support and visibility of residual risks.

Experiment on continuous operation of the Brazilian IEA-R1 research reactor

International Nuclear Information System (INIS)

Freitas Pintaud, M. de

1994-01-01

In order to increase the radioisotope production in the IEA-R1 research reactor at IPEN/CNEN-SP, it has been proposed a change in its operation regime from 8 hours per day and 5 days per week to continuous 48 hours per week. The necessary reactor parameters for this new operation regime were obtained through an experiment in which the reactor was for the first time operated in the new regime. This work presents the principal results from this experiment: xenon reactivity, new shutdown margins, and reactivity loss due to fuel burnup in the new operation regime. (author)

System Architecture for Anti-Ship Ballistic Missile Defense (ASBMD)

Science.gov (United States)

2009-12-01

Execute Search Search Function Link/SATCOM Info Operator Input Output Search Results D etect Function O rganic R esources Avail Receive Remote...Queue O rganic R esources N ot Avail Track Function D etect Function O rganic R esources Avail O rganic R esources N ot Avail Appendix C 153 4.1.2

eddy4R 0.2.0: a DevOps model for community-extensible processing and analysis of eddy-covariance data based on R, Git, Docker, and HDF5

Directory of Open Access Journals (Sweden)

S. Metzger

2017-08-01

Full Text Available Large differences in instrumentation, site setup, data format, and operating system stymie the adoption of a universal computational environment for processing and analyzing eddy-covariance (EC data. This results in limited software applicability and extensibility in addition to often substantial inconsistencies in flux estimates. Addressing these concerns, this paper presents the systematic development of portable, reproducible, and extensible EC software achieved by adopting a development and systems operation (DevOps approach. This software development model is used for the creation of the eddy4R family of EC code packages in the open-source R language for statistical computing. These packages are community developed, iterated via the Git distributed version control system, and wrapped into a portable and reproducible Docker filesystem that is independent of the underlying host operating system. The HDF5 hierarchical data format then provides a streamlined mechanism for highly compressed and fully self-documented data ingest and output. The usefulness of the DevOps approach was evaluated for three test applications. First, the resultant EC processing software was used to analyze standard flux tower data from the first EC instruments installed at a National Ecological Observatory (NEON field site. Second, through an aircraft test application, we demonstrate the modular extensibility of eddy4R to analyze EC data from other platforms. Third, an intercomparison with commercial-grade software showed excellent agreement (R2  =  1.0 for CO2 flux. In conjunction with this study, a Docker image containing the first two eddy4R packages and an executable example workflow, as well as first NEON EC data products are released publicly. We conclude by describing the work remaining to arrive at the automated generation of science-grade EC fluxes and benefits to the science community at large. This software development model is applicable beyond EC

Conformational plasticity of the coiled coil domain of BmrR is required for bmr operator binding - the structure of unliganded BmrR

OpenAIRE

Kumaraswami, Muthiah; Newberry, Kate J.; Brennan, Richard G.

2010-01-01

The multidrug-binding transcription regulator, BmrR, from Bacillus subtilis is a MerR family member that binds to a wide array of cationic lipophilic toxins to activate transcription of the multidrug efflux pump gene, bmr. Transcription activation from the σA-dependent bmr operator requires BmrR to remodel the nonoptimal 19 base pair spacer between the −10 and −35 promoter elements in order to facilitate productive RNA polymerase binding. Despite the availability of several structures of BmrR...

9 CFR 590.412 - Form of official identification symbol and inspection mark.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Form of official identification symbol... PRODUCTS INSPECTION ACT) Identifying and Marking Product § 590.412 Form of official identification symbol... official identification symbol for purposes of this part and, when used, imitated, or simulated in any...

Static QCD potential at rQCD-1: Perturbative expansion and operator-product expansion

International Nuclear Information System (INIS)

Sumino, Y.

2007-01-01

We analyze the static QCD potential V QCD (r) in the distance region 0.1 fm QCD (r) analytically. Higher-order terms are estimated by large-β 0 approximation or by renormalization group, and the renormalization scale is varied around the minimal-sensitivity scale. A 'Coulomb'+linear potential can be identified with the scale-independent and renormalon-free part of the prediction and can be separated from the renormalon-dominating part. (II) In the frame of OPE, we define two types of renormalization schemes for the leading Wilson coefficient. One scheme belongs to the class of conventional factorization schemes. The other scheme belongs to a new class, which is independent of the factorization scale, derived from a generalization of the Coulomb+linear potential of (I). The Wilson coefficient is free from IR renormalons and IR divergences in both schemes. We study properties of the Wilson coefficient and of the corresponding nonperturbative contribution δE US (r) in each scheme. (III) We compare numerically perturbative predictions of the Wilson coefficient and lattice computations of V QCD (r) when n l =0. We confirm either correctness or consistency (within uncertainties) of the theoretical predictions made in (II). Then we perform fits to simultaneously determine δE US (r) and r 0 Λ MS 3-loop (relation between lattice scale and Λ MS ). As for the former quantity, we improve bounds as compared to the previous determination; as for the latter quantity, our analysis provides a new method for its determination. We find that (a) δE US (r)=0 is disfavored, and (b) r 0 Λ MS 3-loop =0.574±0.042. We elucidate the mechanism for the sensitivities and examine sources of errors in detail

A&R challenges for in-space operations. [Automation and Robotic technologies

Science.gov (United States)

Underwood, James

1990-01-01

Automation and robotics (A&R) challenges for in-space operations are examined, with emphasis on the interaction between developing requirements, developing solutions, design concepts, and the nature of the applicability of automation in robotic technologies. Attention is first given to the use of A&R in establishing outposts on the moon and Mars. Then emphasis is placed on the requirements for the assembly of transportation systems in low earth orbit. Concepts of the Space Station which show how the assembly, processing, and checkout of systems in LEO might be accommodated are examined.

77 FR 7613 - Dow Chemical Company; Dow Chemical TRIGA Research Reactor; Facility Operating License No. R-108

Science.gov (United States)

2012-02-13

... NUCLEAR REGULATORY COMMISSION [Docket No. 50-264; NRC-2012-0026] Dow Chemical Company; Dow Chemical TRIGA Research Reactor; Facility Operating License No. R-108 AGENCY: Nuclear Regulatory Commission... Facility Operating License No. R-108 (``Application''), which currently authorizes the Dow Chemical Company...

Crystallization in Zr41.2Ti13.8Cu12.5Ni10Be22.5 bulk metallic glass under pressure

DEFF Research Database (Denmark)

Jiang, Jianzhong; Zhou, T.J.; Rasmussen, Helge Kildahl

2000-01-01

The effect of pressure on the crystallization behavior of the bulk metallic glass-forming Zr41.2Ti13.8Cu12.5Ni10Be22.5 alloy with a wide supercooled liquid region has been investigated by in situ high-pressure and high-temperature x-ray powder diffraction measurements using synchrotron radiation......)], reporting a decrease of the crystallization temperature under pressure in a pressure range of 0-6 GPa for the bulk glass Zr41Ti14Cu12.5Ni9Be22.5C1 alloy. Compressibility with a volume reduction of approximately 22% at room temperature does not induce crystallization in the Zr41.2Ti13.8Cu12.5Ni10Be22.5 bulk...... glass alloy. This indicates that the densification effect induced by pressure in the pressure range investigated plays a minor role in the crystallization behavior of this bulk glass alloy. The different crystallization behavior of the carbon-free and the carbon-containing glassy alloys has been...

A set of professional working ability indicators of military operators

Directory of Open Access Journals (Sweden)

Mykola Korchahin

2017-08-01

Full Text Available Purpose: determination of indicators of professional work capacity and their impact on the success of professional activity of military operators in the cycle of alert duty. Material & Methods: indicators of the professional capacity of military operators were determined through theoretical analysis, systematization and generalization of data from scientific and methodological sources, medical-biological, psycho-diagnostic methods and mathematical methods of processing the results of the study. Result: it is determined that the most informative indirect indicators of the professional capacity of military operators of the contract service of the Air Forces of the Armed Forces of Ukraine is: physical condition, psycho-emotional state, physical performance, aerobic endurance, static endurance of back muscles, neck and the abs, the speed of perception, memory, concentration and shifting attention. The correlation dependence of the level of professional preparedness of military operators on indirect indices of professional work capacity: physical fitness (r=0,58, psycho-emotional state (r=0,51, physical performance (r=0,34, aerobic endurance (r=0.59, static endurance of the muscles of the back and neck (r=0,52, static endurance of the abs muscles (r=0,48, simple sensorimotor reaction (r=0,44, short-term (operational memory (r=0,40, concentration and attention switching (r=0,46. Conclusion: a complex characteristic of the indicators of psycho-physiological functions of the body of a specialist can be used to assess the dynamics and prediction of the professional capacity of military operators of the Air Force in the cycle of alert duty.

Theoretical Foundations of the Web: Cognition, Communication, and Co-Operation. Towards an Understanding of Web 1.0, 2.0, 3.0

Directory of Open Access Journals (Sweden)

Robert Bichler

2010-02-01

Full Text Available Currently, there is much talk of Web 2.0 and Social Software. A common understanding of these notions is not yet in existence. The question of what makes Social Software social has thus far also remained unacknowledged. In this paper we provide a theoretical understanding of these notions by outlining a model of the Web as a techno-social system that enhances human cognition towards communication and co-operation. According to this understanding, we identify three qualities of the Web, namely Web 1.0 as a Web of cognition, Web 2.0 as a Web of human communication, and Web 3.0 as a Web of co-operation. We use the terms Web 1.0, Web 2.0, Web 3.0 not in a technical sense, but for describing and characterizing the social dynamics and information processes that are part of the Internet.

R-matrix arising from affine Hecke algebras and its application to Macdonald's difference operators

International Nuclear Information System (INIS)

Kato, Shinichi

1994-01-01

We shall give a certain trigonometric R-matrix associated with each root system by using affine Hecke algebras. From this R-matrix, we derive a quantum Knizhnik-Zamolodchikov equation after Cherednik, and show that the solutions of this KZ equation yield eigenfunctions of Macdonald's difference operators. (orig.)

The ATLAS Tier-0 Overview and operational experience

CERN Document Server

Elsing, M; Nairz, A; Negri, G

2010-01-01

Within the ATLAS hierarchical, multi-tier computing infrastructure, the Tier-0 centre at CERN is mainly responsible for prompt processing of the raw data coming from the online DAQ system, to archive the raw and derived data on tape, to register the data with the relevant catalogues and to distribute them to the associated Tier-1 centers. The Tier-0 is already fully functional. It has been successfully participating in all cosmic and commissioning data taking since May 2007, and was ramped up to its foreseen full size, performance and throughput for the cosmic (and short single-beam) run periods between July and October 2008. Data and work flows for collision data taking were exercised in several "Full Dress Rehearsals" (FDRs) in the course of 2008. The transition from an expert to a shifter-based system was successfully established in July 2008. This article will give an overview of the Tier-0 system, its data and work flows, and operations model. It will review the operational experience gained in cosmic, c...

R=0 spacetimes and self-dual Lorentzian wormholes

International Nuclear Information System (INIS)

Dadhich, Naresh; Kar, Sayan; Mukherjee, Sailajananda; Visser, Matt

2002-01-01

A two-parameter family of spherically symmetric, static Lorentzian wormholes is obtained as the general solution of the equation ρ=ρ t =0, where ρ=T ij u i u j , ρ t =(T ij -(1/2)Tg ij )u i u j , and u i u i =-1. This equation characterizes a class of spacetimes which are 'self-dual' (in the sense of electrogravity duality). The class includes the Schwarzschild black hole, a family of naked singularities, and a disjoint family of Lorentzian wormholes, all of which have a vanishing scalar curvature (R=0). The properties of these spacetimes are discussed. Using isotropic coordinates we delineate clearly the domains of parameter space for which wormholes, nakedly singular spacetimes and the Schwarzschild black hole can be obtained. A model for the required 'exotic' stress-energy is discussed, and the notion of traversability for the wormholes is also examined

29 CFR 2580.412-2 - Plans exempt from the coverage of section 13.

Science.gov (United States)

2010-07-01

... whole or in part, of dealing with employers concerning an employee welfare or pension benefit plan, or... Section 2580.412-2 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT OF LABOR TEMPORARY BONDING RULES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF...

Crystal structure of (1R,3S,8R,11R-11-acetyl-3,7,7-trimethyl-10-oxatricyclo[6.4.0.01,3]dodecan-9-one

Directory of Open Access Journals (Sweden)

Abdoullah Bismoussa

2015-12-01

Full Text Available The title compound, C16H24O3, is built up from three fused rings, a six-membered, a seven-membered and a three-membered ring. The absolute configuration of the title compound was determined as (1R,3S,8R,11R based on the synthetic pathway. The six-membered ring has an half-chair conformation whereas the seven-membered ring displays a boat conformation. In the cyrstal, C—H...O hydrogen bonds build up a two-dimensional network parallel to (0 0 1. The crystal studied was an inversion twin with a minor twin component of 34%.

Cholesterol modulates Orai1 channel function

Czech Academy of Sciences Publication Activity Database

Derler, I.; Jardin, I.; Stathopulos, P.B.; Muik, M.; Fahrner, M.; Zayats, Vasilina; Pandey, Saurabh Kumar; Poteser, M.; Lackner, B.; Absolonova, M.; Schindl, R.; Groschner, K.; Ettrich, Rüdiger; Ikura, M.; Romanin, Ch.

2016-01-01

Roč. 9, č. 412 (2016), ra10 ISSN 1945-0877 R&D Projects: GA ČR GA13-21053S Institutional support: RVO:61388971 Keywords : ACTIVATES CRAC CHANNELS * OPERATED CA2+ ENTRY * PLASMA-MEMBRANE Subject RIV: CE - Biochemistry Impact factor: 6.494, year: 2016

The theological significance of the Isaiah citation in Mark 4:12 ...

African Journals Online (AJOL)

The well-known passage Mark 4:1–34 is no stranger to New Testament scientific scrutiny, not to even mention the hotly debated phrases in Mark 4:10–12. To avoid repetition, the aim with this article is to determine the extent of the impact the Isaiah 6:9–10 citation in Mark 4:12 might have had on the interpretation and ...

Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR.

Science.gov (United States)

Kumaraswami, Muthiah; Newberry, Kate J; Brennan, Richard G

2010-04-30

The multidrug-binding transcription regulator BmrR from Bacillus subtilis is a MerR family member that binds to a wide array of cationic lipophilic toxins to activate the transcription of the multidrug efflux pump gene bmr. Transcription activation from the sigma(A)-dependent bmr operator requires BmrR to remodel the nonoptimal 19-bp spacer between the -10 promoter element and the -35 promoter element in order to facilitate productive RNA polymerase binding. Despite the availability of several structures of BmrR bound to DNA and drugs, the lack of a BmrR structure in its unliganded or apo (DNA free and drug free) state hinders our full understanding of the structural transitions required for DNA binding and transcription activation. Here, we report the crystal structure of the constitutively active, unliganded BmrR mutant BmrR(E253Q/R275E). Superposition of the ligand-free (apo BmrR(E253Q/R275E)) and DNA-bound BmrR structures reveals that apo BmrR must undergo significant rearrangement in order to assume the DNA-bound conformation, including an outward rotation of minor groove binding wings, an inward movement of helix-turn-helix motifs, and a downward relocation of pliable coiled-coil helices. Computational analysis of the DNA-free and DNA-bound structures reveals a flexible joint that is located at the center of the coiled-coil helices. This region, which is composed of residues 94 through 98, overlaps the helical bulge that is observed only in the apo BmrR structure. This conformational hinge is likely common to other MerR family members with large effector-binding domains, but appears to be missing from the smaller metal-binding MerR family members. Interestingly, the center-to-center distance of the recognition helices of apo BmrR is 34 A and suggests that the conformational change from the apo BmrR structure to the bmr operator-bound BmrR structure is initiated by the binding of this transcription activator to a more B-DNA-like conformation. (c) 2010 Elsevier

(1R,2R,3R,4R,5S-2,3-Bis[(2S′-2-acetoxy-2-phenylacetoxy]-4-azido-1-[(2,4-dinitrophenylhydrazonomethyl]bicyclo[3.1.0]hexane

Directory of Open Access Journals (Sweden)

Robert McDonald

2008-02-01

Full Text Available In the title compound, C38H29N7O12, the five-membered ring adopts an envelope conformation in which the `flap' is cis to the cyclopropane group. This conformation is similar to those of other bicyclo[3.1.0]hexane analogues for which crystal structures have been reported. The absolute configuration of the stereogenic centers on the cyclopentane ring, as determined by comparison with the known configurations of the stereogenic centers in the (2S-2-acetoxy-2-phenylacetoxy groups, is 1(R, 2(R, 3(R, 4(R and 5(S. An intramolecular N—H...O hydrogen bond is present.

On the Similarity of Sturm-Liouville Operators with Non-Hermitian Boundary Conditions to Self-Adjoint and Normal Operators

Czech Academy of Sciences Publication Activity Database

Krejčiřík, David; Siegl, Petr; Železný, Jakub

2014-01-01

Roč. 8, č. 1 (2014), s. 255-281 ISSN 1661-8254 R&D Projects: GA MŠk LC06002; GA MŠk LC527; GA ČR GAP203/11/0701 Grant - others:GA ČR(CZ) GD202/08/H072 Institutional support: RVO:61389005 Keywords : Sturm-Liouville operators * non-symmetric Robin boundary conditions * similarity to normal or self-adjoint operators * discrete spectral operator * complex symmetric operator * PT-symmetry * metric operator * C operator * Hilbert- Schmidt operators Subject RIV: BE - Theoretical Physics Impact factor: 0.545, year: 2014

New digital control system for the operation of the Colombian research reactor IAN-R1

International Nuclear Information System (INIS)

Celis del A, L.; Rivero, T.; Bucio, F.; Ramirez, R.; Segovia, A.; Palacios, J.

2015-09-01

En 2011, Mexico won the Colombian international tender for the renewal of instrumentation and control of the IAN-R1 Reactor, to Argentina and the United States. This paper presents the design criteria and the development made for the new digital control system installed in the Colombian nuclear reactor IAN-R1, which is based on a redundant and diverse architecture, which provides increased availability, reliability and safety in the reactor operation. This control system and associated instrumentation met all national export requirements, with the safety requirements established by the IAEA as well as the requirements demanded by the Colombian Regulatory Body in nuclear matter. On August 20, 2012, the Colombian IAN-R1 reactor reached its first criticality controlled with the new system developed at Instituto Nacional de Investigaciones Nucleares (ININ). On September 14, 2012, the new control system of the Colombian IAN-R1 reactor was officially handed over to the Colombian authorities, this being the first time that Mexico exported nuclear technology through the ININ. Currently the reactor is operating successfully with the new control system, and has an operating license for 5 years. (Author)

Explaining the R_K and R_{K^*} anomalies

Science.gov (United States)

Ghosh, Diptimoy

2017-10-01

Recent LHCb results on R_{K^*}, the ratio of the branching fractions of B → K^* μ ^+ μ ^- to that of B → K^* e^+ e^-, for the dilepton invariant mass bins q^2 ≡ m_{ℓ ℓ }^2 = [0.045-1.1] GeV^2 and [1.1-6] GeV^2 show approximately 2.5 σ deviations from the corresponding Standard Model prediction in each of the bins. This, when combined with the measurement of R_K (q^2=[1-6] GeV^2), a similar ratio for the decay to a pseudo-scalar meson, highly suggests lepton non-universal new physics in semi-leptonic B meson decays. In this work, we perform a model independent analysis of these potential new physics signals and identify the operators that do the best job in satisfying all these measurements. We show that heavy new physics, giving rise to q^2 independent local 4-Fermi operators of scalar, pseudo-scalar, vector or axial-vector type, is unable to explain all the three measurements simultaneously, in particular R_{K^*} in the bin [0.045-1.1], within their experimental 1σ regions. We point out the possibility to explain R_{K^*} in the low bin by an additional light (≲ 20 {MeV}) vector boson with appropriate coupling strengths to (\\bar{b} s) and (\\bar{e} e).

Leaching Studies on ACR-1000{sup R} Fuel Under Reactor Operating Conditions

Energy Technology Data Exchange (ETDEWEB)

Sunder, S. [Atomic Energy of Canada Limited, Fuel and Fuel Channel Safety Branch, Chalk River, Ontario, K0J 1J0 (Canada)

2009-06-15

ACR-1000{sup R} is the latest nuclear power reactor being developed by AECL. The ACR-1000 fuel uses a modified CANFLEX{sup R} fuel bundle that contains low-enriched uranium and pellets of burnable neutron absorbers (BNA) in a central element. Dysprosium and gadolinium are used as the burnable neutron absorbers and are present as oxides in a 'fully-stabilized' zirconia matrix. The BNA material in the centre element is designed to limit the coolant void reactivity of the reactor core during postulated loss-of-coolant accidents. As part of the ACR-1000 fuel development, the stability of the BNA material under conditions associated with defects of the Zircaloy sheathing of the BNA central element has been investigated. The results of these tests can be used to demonstrate the phase stability and leaching behaviour of the ACR-1000 fuel under reactor operating conditions. The samples were disks, about 3-4 mm thick, obtained from BNA pellets and Candu fuel (natural uranium UO{sub 2}) pellets (the UO{sub 2} measurements provide a reference point). Leaching tests were carried out in light water at 325 deg. C, above the maximum coolant temperature in an ACR-1000 fuel channel during normal operating conditions (319 deg. C). This temperature also bounds the maximum operating temperature for the current Candu reactors (311 deg. C). The initial pH of the solution (measured at room temperature) used in the leaching tests was 10.3. The leach rates were determined by monitoring the amount of metals leached into solutions. Leaching tests were also carried out with BNA pellet samples in the presence of Zr-2.5%Nb pressure tube coupons to determine the effects, if any, of the presence of pressure tube material on leach rates. Other leaching tests with BNA pellet samples and UO{sub 2} pellets were conducted at 80 deg. C to study the effects of temperature on the leach rates. The temperature of 80 deg. C was selected as representative of typical shutdown temperatures

A dictionary between R-operators, on-shell graphs and Yangian algebras

Energy Technology Data Exchange (ETDEWEB)

Broedel, Johannes; Leeuw, Marius de; Rosso, Matteo [Institut für Theoretische Physik, Eidgenössische Technische Hochschule Zürich,Wolfgang-Pauli-Strasse 27, 8093 Zürich (Switzerland)

2014-06-27

We translate between different formulations of Yangian invariants relevant for the computation of tree-level scattering amplitudes in N=4 super-Yang–Mills theory. While the R-operator formulation allows to relate scattering amplitudes to structures well known from integrability, it can equally well be connected to the permutations encoded by on-shell graphs.

Incentives to strengthen international co-operation in R and D for advanced nuclear power technology

International Nuclear Information System (INIS)

Balthesen, E.; Bakunyaev, A.D.; Gibson, I.H.; Hosemann, J.P.; Tavoni, R.; Versteegh, A.M.

1993-01-01

This paper is concerned with the need for International Co-operation in R and D for Advanced Reactors in order to maintain options for the future deployment of nuclear power against the current background of declining R and D capability in Europe

Involvement of Calmodulin and Calmodulin-like Proteins in Plant Responses to Abiotic Stresses

Directory of Open Access Journals (Sweden)

B W Poovaiah

2015-08-01

Full Text Available Transient changes in intracellular Ca2+ concentration have been well recognized to act as cell signals coupling various environmental stimuli to appropriate physiological responses with accuracy and specificity in plants. Calmodulin (CaM and calmodulin-like proteins (CMLs are major Ca2+ sensors, playing critical roles in interpreting encrypted Ca2+ signals. Ca2+-loaded CaM/CMLs interact and regulate a broad spectrum of target proteins such as channels/pumps/antiporters for various ions, transcription factors, protein kinases, protein phosphatases, metabolic enzymes and proteins with unknown biochemical functions. Many of the target proteins of CaM/CMLs directly or indirectly regulate plant responses to environmental stresses. Basic information about stimulus-induced Ca2+ signal and overview of Ca2+ signal perception and transduction are briefly discussed in the beginning of this review. How CaM/CMLs are involved in regulating plant responses to abiotic stresses are emphasized in this review. Exciting progress has been made in the past several years, such as the elucidation of Ca2+/CaM-mediated regulation of AtSR1/CAMTA3 and plant responses to chilling and freezing stresses, Ca2+/CaM-mediated regulation of CAT3, MAPK8 and MKP1 in homeostasis control of ROS signals, discovery of CaM7 as a DNA-binding transcription factor regulating plant response to light signals. However, many key questions in Ca2+/CaM-mediated signaling warrant further investigation. Ca2+/CaM-mediated regulation of most of the known target proteins is presumed based on their interaction. The downstream targets of CMLs are mostly unknown, and how specificity of Ca2+ signaling could be realized through the actions of CaM/CMLs and their target proteins is largely unknown. Future breakthroughs in Ca2+/CaM-mediated signaling will not only improve our understanding of how plants respond to environmental stresses, but also provide the knowledge base to improve stress-tolerance of crops.

Adsorption of Procion Blue MX-R dye from aqueous solutions by lignin chemically modified with aluminium and manganese

International Nuclear Information System (INIS)

Adebayo, Matthew A.; Prola, Lizie D.T.; Lima, Eder C.; Puchana-Rosero, M.J.; Cataluña, Renato; Saucier, Caroline; Umpierres, Cibele S.; Vaghetti, Julio C.P.; Silva, Leandro G. da; Ruggiero, Reinaldo

2014-01-01

Graphical abstract: - Highlights: • Complexes of carboxy-methylated lignin with Al and Mn were used as adsorbents. • The optimum adsorption conditions were achieved at pH 2 and 298 K. • Maximum adsorption capacities are 73.52 mg g −1 (CML-Al) and 55.16 mg g −1 (CML-Mn). • CML-Al could remove ca. 95.83% of dye-contaminated industrial effluents. • CML-Al and CML-Mn are effective for treatment of simulated dye-house effluents. - Abstract: A macromolecule, CML, was obtained by purifying and carboxy-methylating the lignin generated from acid hydrolysis of sugarcane bagasse during bioethanol production from biomass. The CMLs complexed with Al 3+ (CML-Al) and Mn 2+ (CML-Mn) were utilised for the removal of a textile dye, Procion Blue MX-R (PB), from aqueous solutions. CML-Al and CML-Mn were characterised using Fourier transform infrared spectroscopy (FTIR), scanning differential calorimetry (SDC), scanning electron microscopy (SEM) and pH PZC . The established optimum pH and contact time were 2.0 and 5 h, respectively. The kinetic and equilibrium data fit into the general order kinetic model and Liu isotherm model, respectively. The CML-Al and CML-Mn have respective values of maximum adsorption capacities of 73.52 and 55.16 mg g −1 at 298 K. Four cycles of adsorption/desorption experiments were performed attaining regenerations of up to 98.33% (CML-Al) and 98.08% (CML-Mn) from dye-loaded adsorbents, using 50% acetone + 50% of 0.05 mol L −1 NaOH. The CML-Al removed ca. 93.97% while CML-Mn removed ca. 75.91% of simulated dye house effluents

A cobalt-free perovskite-type La{sub 0.6}Sr{sub 0.4}Fe{sub 0.9}Cr{sub 0.1}O{sub 3-{alpha}} cathode for proton-conducting intermediate temperature solid oxide fuel cells

Energy Technology Data Exchange (ETDEWEB)

Ding, Zuolong; Yang, Zhijie; Zhao, Dongmei; Deng, Xuli [Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123 (China); Ma, Guilin, E-mail: 32uumagl@suda.edu.cn [Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123 (China)

2013-02-15

Highlights: Black-Right-Pointing-Pointer A cobalt-free cathode material LSFC10 for IT-SOFCs was prepared and studied in detail. Black-Right-Pointing-Pointer The conductivity of LSFC10 reached 138 S cm{sup -1} under oxygen at 550 Degree-Sign C. Black-Right-Pointing-Pointer An anode-supported BZCY electrolyte membrane was successfully fabricated by a simple spin coating process. Black-Right-Pointing-Pointer Power density of the ceramic membrane fuel cell using LSFC10 as cathode reached 412 mW cm{sup -2} at 700 Degree-Sign C. - Abstract: A cobalt-free perovskite-type cathode material La{sub 0.6}Sr{sub 0.4}Fe{sub 0.9}Cr{sub 0.1}O{sub 3-{alpha}} (LSFC10) was prepared by a citric acid-nitrate process and investigated as a potential cathode material for proton-conducting intermediate-temperature solid oxide fuel cells (IT-SOFCs). The maximum conductivity of LSFC10 reached 138 S cm{sup -1} under oxygen at 550 Degree-Sign C. A Ni-BZCY composite anode-supported proton-conducting BaZr{sub 0.1}Ce{sub 0.7}Y{sub 0.2}O{sub 3-{alpha}} (BZCY) electrolyte membrane was successfully fabricated by a simple, cost-effective spin coating process. The peak power densities of the H{sub 2}/O{sub 2} fuel cell using BZCY electrolyte membrane, Ni-BZCY composite anode and LSFC10 cathode reached 412 mW cm{sup -2}, and the interfacial polarization resistance for the fuel cell was as low as 0.19 {Omega} cm{sup 2} under open circuit conditions, at 700 Degree-Sign C. These results reveal LSFC10 is a suitable cathode material for proton-conducting IT-SOFCs.

42 CFR 412.517 - Revision of LTC-DRG group classifications and weighting factors.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Revision of LTC-DRG group classifications and... the LTC-DRG classifications and recalibration of the weighting factors described in paragraph (a) of... SERVICES Prospective Payment System for Long-Term Care Hospitals § 412.517 Revision of LTC-DRG group...

29 CFR 2580.412-22 - Interests held in agents, brokers and surety companies.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Interests held in agents, brokers and surety companies... SECURITY ACT OF 1974 TEMPORARY BONDING RULES Qualified Agents, Brokers and Surety Companies for the Placing of Bonds § 2580.412-22 Interests held in agents, brokers and surety companies. Section 13(c...

Transition of R&D into Operations at Fleet Numerical Meteorology and Oceanography Center

Science.gov (United States)

Clancy, R. M.

2006-12-01

R&D activity, the Marine Meteorology Division of the Naval Research Laboratory (NRL Code 7500). NRL Code 7500 is a world-class research organization, with focus on weather-related support for the warfighter. Fleet Numerical and NRL Code 7500 share space, data, software and computer systems, and together represent one of the largest concentrations of weather-related intellectual capital in the nation. As documented, for example, by the Board on Atmospheric Sciences and Climate (BASC) of the National Research Council, investment in R&D is crucial for maintaining state-of-the-art operational Numerical Weather Prediction (NWP) capabilities (see BASC, 1998). And collocation and close cooperation between research and operations, such as exists between NRL Code 7500 and Fleet Numerical, is the optimum arrangement for transitioning R&D quickly and cost-effectively into new and improved operational weather prediction capabilities.

M4/12 package project - development of a package for transport of new MOX fuel in Europe

Energy Technology Data Exchange (ETDEWEB)

Kaye, B.R.; Porter, I.; Ashley, P. [BNFL, Warrington, Cheshire (United Kingdom)

2004-07-01

BNFL has a requirement to deliver new MOX fuel from the Sellafield MOX Plant (SMP) to its customers in mainland Europe. To satisfy this requirement, a transport system has been developed which complies with national and international regulations and conventions relating to the transport of Category 1 materials. Fundamental to this system is the transport package. BNFL has designed, developed, and is manufacturing a new transport package, the M4/12, This paper gives a brief overview of the overall transport system and then goes on to describe the development of the M4/12 package with particular emphasis on the novel features of the design.

M4/12 package project - development of a package for transport of new MOX fuel in Europe

International Nuclear Information System (INIS)

Kaye, B.R.; Porter, I.; Ashley, P.

2004-01-01

BNFL has a requirement to deliver new MOX fuel from the Sellafield MOX Plant (SMP) to its customers in mainland Europe. To satisfy this requirement, a transport system has been developed which complies with national and international regulations and conventions relating to the transport of Category 1 materials. Fundamental to this system is the transport package. BNFL has designed, developed, and is manufacturing a new transport package, the M4/12, This paper gives a brief overview of the overall transport system and then goes on to describe the development of the M4/12 package with particular emphasis on the novel features of the design

13 CFR 121.412 - What are the size procedures for partial small business set-asides?

Science.gov (United States)

2010-01-01

... Requirements for Government Procurement § 121.412 What are the size procedures for partial small business set... portion of a procurement, and is not required to qualify as a small business for the unrestricted portion. ...

Baxter Q-operator and separation of variables for the open SL(2, R) spin chain

International Nuclear Information System (INIS)

Derkachov, Sergey E.; Korchemsky, Gregory P.; Manashov, Alexander N.

2003-01-01

We construct the Baxter Q-operator and the representation of the Separated Variables (SoV) for the homogeneous open SL(2, R) spin chain. Applying the diagrammatical approach, we calculate Sklyanin's integration measure in the separated variables and obtain the solution to the spectral problem for the model in terms of the eigenvalues of the Q-operator. We show that the transition kernel to the SoV representation is factorized into the product of certain operators each depending on a single separated variable. As a consequence, it has a universal pyramid-like form that has been already observed for vari- ous quantum integrable models such as periodic Toda chain, closed SL(2, R) and SL(2, C) spin chains. (author)

Estudo comparativo entre bupivacaína a 0,5% e mistura enantiomérica de bupivacaína (S75-R25 a 0,5% em anestesia peridural Estudio comparativo entre bupivacaína a 0,5% y mezcla enantiomérica de bupivacaína (S75-R25 a 0,5% en anestesia peridural Comparative study between 0.5% bupivacaine and 0.5% enantiomeric mixture of bupivacaine (S75-R25 in epidural anesthesia

Directory of Open Access Journals (Sweden)

Rosane Fossatti Gonçalves

2003-04-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A mistura enantiomérica de bupivacaína (S75-R25 vem sendo empregada pela sua propriedade anestésica com menor toxicidade do que a bupivacaína racêmica. O objetivo deste estudo é comparar a bupivacaína a 0,5% com a mistura enantiomérica de bupivacaína a 0,5% (S75-R25 em anestesia peridural. MÉTODO: Foram incluídos no estudo 44 pacientes divididos em dois grupos (n=22 denominados de Bupivacaína e S75-R25. Os pacientes foram medicados com midazolam por via venosa. A anestesia peridural foi realizada no espaço L3-L4 ou L2-L3, e administrado 16 a 24 ml da solução do anestésico local. O grupo Bupivacaína recebeu bupivacaína a 0,5% com vasoconstritor. O grupo S75-R25 recebeu a mistura enantiomérica de bupivacaína a 0,5% com vasoconstritor. Foram avaliados a temperatura do membro inferior antes e após o bloqueio peridural, o tempo de latência do bloqueio, o tipo de alteração referida pelo paciente, possíveis falhas sensoriais, nível sensorial metamérico e o grau de bloqueio motor. Na sala de recuperação pós-anestésica, foi anotado o tempo de requisição do primeiro analgésico. RESULTADOS: Fizeram parte da avaliação final 41 pacientes. Os grupos foram demograficamente semelhantes. A dose per-operatória de midazolam, o volume de anestésico local por via peridural, o tempo de latência para a instalação do bloqueio, falhas sensoriais a picada da agulha, temperatura do membro inferior nos diferentes tempos, o tipo de sensação parestésica, e o nível anestésico em dermátomos foram semelhantes entre os grupos. O grau de bloqueio motor foi mais intenso para o grupo Bupivacaína, comparado ao grupo S75-R25 (p = 0,0117. O tempo para requisição do primeiro analgésico no período pós-operatório foi superior para o grupo S75-R25, comparado ao grupo Bupivacaína (596 ± 436 minutos versus 463 ± 270 minutos, respectivamente; p = 0,04572. A incidência de efeitos adversos foi semelhante entre

0 + 5 Vascular Surgery Residents' Operative Experience in General Surgery: An Analysis of Operative Logs from 12 Integrated Programs.

Science.gov (United States)

Smith, Brigitte K; Kang, P Chulhi; McAninch, Chris; Leverson, Glen; Sullivan, Sarah; Mitchell, Erica L

2016-01-01

Integrated (0 + 5) vascular surgery (VS) residency programs must include 24 months of training in core general surgery. The Accreditation Council for Graduate Medical Education currently does not require specific case numbers in general surgery for 0 + 5 trainees; however, program directors have structured this time to optimize operative experience. The aim of this study is to determine the case volume and type of cases that VS residents are exposed to during their core surgery training. Accreditation council for graduate medical education operative logs for current 0 + 5 VS residents were obtained and retrospectively reviewed to determine general surgery case volume and distribution between open and laparoscopic cases performed. Standard statistical methods were applied. A total of 12 integrated VS residency programs provided operative case logs for current residents. A total of 41 integrated VS residents in clinical years 2 through 5. During the postgraduate year-1 training year, residents participated in significantly more open than laparoscopic general surgery cases (p surgery cases are hernia repair (20%), skin and soft tissue (7.4%), and breast (6.3%). Residents in programs with core surgery over 3 years participated in significantly more general surgery operations compared with residents in programs with core surgery spread out over 4 years (p = 0.035). 0 + 5 VS residents perform significantly more open operations than laparoscopic operations during their core surgery training. The majority of these operations are minor, nonabdominal procedures. The 0 + 5 VS residency program general surgery operative training requirements should be reevaluated and case minimums defined. The general surgery training component of 0 + 5 VS residencies may need to be restructured to meet the needs of current and future trainees. Copyright © 2016 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

Stability and Unimolecular Reactivity of Palladate(II) Complexes [Ln PdR3 ]- (L=Phosphine, R=Organyl, n=0 and 1).

Science.gov (United States)

Kolter, Marlene; Koszinowski, Konrad

2016-10-24

The reduction of Pd II precatalysts to catalytically active Pd 0 species is a key step in many palladium-mediated cross-coupling reactions. Besides phosphines, the stoichiometrically used organometallic reagents can afford this reduction, but do so in a poorly understood way. To elucidate the mechanism of this reaction, we have treated solutions of Pd(OAc) 2 and a phosphine ligand L in tetrahydrofuran with RMgCl (R=Ph, Bn, Bu) as well as other organometallic reagents. Analysis of these model systems by electrospray- ionization mass spectrometry found palladate(II) complexes [L n PdR 3 ] - (n=0 and 1), thus pointing to the occurrence of transmetallation reactions. Upon gas-phase fragmentation, the [L n PdR 3 ] - anions preferentially underwent a reductive elimination to yield Pd 0 species. The sequence of the transmetallation and reductive elimination, thus, constitutes a feasible mechanism for the reduction of the Pd(OAc) 2 precatalyst. Other species of interest observed include the Pd IV complex [PdBn 5 ] - , which did not fragment via a reductive elimination but lost BnH instead. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

ROS (Robot Operating System) für Automotive

OpenAIRE

Bubeck, Alexander

2014-01-01

- Introduction into the Robot Operating System - Open Source in the automotive industries - Application of ROS in the automotive industry - ROS navigation - ROS with real time control - ROS in the embedded world - Outlook: ROS 2.0 - Summary

The ATLAS Tier-0: Overview and operational experience

International Nuclear Information System (INIS)

Elsing, Markus; Goossens, Luc; Nairz, Armin; Negri, Guido

2010-01-01

Within the ATLAS hierarchical, multi-tier computing infrastructure, the Tier-0 centre at CERN is mainly responsible for prompt processing of the raw data coming from the online DAQ system, to archive the raw and derived data on tape, to register the data with the relevant catalogues and to distribute them to the associated Tier-1 centers. The Tier-0 is already fully functional. It has been successfully participating in all cosmic and commissioning data taking since May 2007, and was ramped up to its foreseen full size, performance and throughput for the cosmic (and short single-beam) run periods between July and October 2008. Data and work flows for collision data taking were exercised in several 'Full Dress Rehearsals' (FDRs) in the course of 2008. The transition from an expert to a shifter-based system was successfully established in July 2008. This article will give an overview of the Tier-0 system, its data and work flows, and operations model. It will review the operational experience gained in cosmic, commissioning, and FDR exercises during the past year. And it will give an outlook on planned developments and the evolution of the system towards first collision data taking expected now in late Autumn 2009.

The ATLAS Tier-0: Overview and operational experience

Science.gov (United States)

Elsing, Markus; Goossens, Luc; Nairz, Armin; Negri, Guido

2010-04-01

Within the ATLAS hierarchical, multi-tier computing infrastructure, the Tier-0 centre at CERN is mainly responsible for prompt processing of the raw data coming from the online DAQ system, to archive the raw and derived data on tape, to register the data with the relevant catalogues and to distribute them to the associated Tier-1 centers. The Tier-0 is already fully functional. It has been successfully participating in all cosmic and commissioning data taking since May 2007, and was ramped up to its foreseen full size, performance and throughput for the cosmic (and short single-beam) run periods between July and October 2008. Data and work flows for collision data taking were exercised in several "Full Dress Rehearsals" (FDRs) in the course of 2008. The transition from an expert to a shifter-based system was successfully established in July 2008. This article will give an overview of the Tier-0 system, its data and work flows, and operations model. It will review the operational experience gained in cosmic, commissioning, and FDR exercises during the past year. And it will give an outlook on planned developments and the evolution of the system towards first collision data taking expected now in late Autumn 2009.

29 CFR 2580.412-36 - Application of 13(c) to “party in interest”.

Science.gov (United States)

2010-07-01

..., custodian, counsel, or employee of any employee welfare benefit plan or a person providing benefit plan... Section 2580.412-36 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT OF LABOR TEMPORARY BONDING RULES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF...

On the definition and utilization of heritable variation among hosts in reproduction ratio R0 for infectious diseases.

Science.gov (United States)

Anche, M T; de Jong, M C M; Bijma, P

2014-10-01

Infectious diseases have a major role in evolution by natural selection and pose a worldwide concern in livestock. Understanding quantitative genetics of infectious diseases, therefore, is essential both for understanding the consequences of natural selection and for designing artificial selection schemes in agriculture. The basic reproduction ratio, R0, is the key parameter determining risk and severity of infectious diseases. Genetic improvement for control of infectious diseases in host populations should therefore aim at reducing R0. This requires definitions of breeding value and heritable variation for R0, and understanding of mechanisms determining response to selection. This is challenging, as R0 is an emergent trait arising from interactions among individuals in the population. Here we show how to define breeding value and heritable variation for R0 for genetically heterogeneous host populations. Furthermore, we identify mechanisms determining utilization of heritable variation for R0. Using indirect genetic effects, next-generation matrices and a SIR (Susceptible, Infected and Recovered) model, we show that an individual's breeding value for R0 is a function of its own allele frequencies for susceptibility and infectivity and of population average susceptibility and infectivity. When interacting individuals are unrelated, selection for individual disease status captures heritable variation in susceptibility only, yielding limited response in R0. With related individuals, however, there is a secondary selection process, which also captures heritable variation in infectivity and additional variation in susceptibility, yielding substantially greater response. This shows that genetic variation in susceptibility represents an indirect genetic effect. As a consequence, response in R0 increased substantially when interacting individuals were genetically related.

Omvårdnadsåtgärder för att minska rädsla, oro och ångest hos barn 0-18 år i samband med en röntgenundersökning : En litteraturstudie

OpenAIRE

Mohsen, Nadja; Imsirovic, Amela

2016-01-01

Bakgrund: Att besöka en röntgenavdelning kan vara något nytt och skrämmande för många barn. Den nya miljön kan orsaka rädsla, oro och ångest hos barn. Därför är det viktigt att röntgensjuksköterskan har kunskap om barnets behov för att upplevelsen på röntgenavdelningen ska vara så bra som möjligt. Syfte: Syftet med den här studien är att beskriva omvårdnadsåtgärder för att minska rädsla, oro och ångest hos barn 0-18 år i samband med röntgenundersökning. Metod: Detta arbete är en litteraturstu...

Reversible operation of microtubular solid oxide cells using La0.6Sr0.4Co0.2Fe0.8O3-δ-Ce0.9Gd0.1O2-δ oxygen electrodes

Science.gov (United States)

López-Robledo, M. J.; Laguna-Bercero, M. A.; Larrea, A.; Orera, V. M.

2018-02-01

Yttria stabilized zirconia (YSZ) based microtubular solid oxide fuel cells (mT-SOFCs) using La0.6Sr0.4Co0.2Fe0.8O3-δ (LSCF) and Ce0.9Gd0.1O2-δ (GDC) as the oxygen electrode, along with a porous GDC electrolyte-electrode barrier layer, were fabricated and characterized in both fuel cell (SOFC) and electrolysis (SOEC) operation modes. The cells were anode-supported, the NiO-YSZ microtubular supports being made by Powder Extrusion Moulding (PEM). The cells showed power densities of 695 mW cm-2 at 800 °C and 0.7 V in SOFC mode, and of 845 mA cm-2 at 800 °C and 1.3 V in SOEC mode. AC impedance experiments performed under different potential loads demonstrated the reversibility of the cells. These results showed that these cells, prepared with a method suitable for using on an industrial scale, are highly reproducible and reliable, as well as very competitive as reversible SOFC-SOEC devices operating at intermediate temperatures.

MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry.

Science.gov (United States)

Jain, Miten; Tyson, John R; Loose, Matthew; Ip, Camilla L C; Eccles, David A; O'Grady, Justin; Malla, Sunir; Leggett, Richard M; Wallerman, Ola; Jansen, Hans J; Zalunin, Vadim; Birney, Ewan; Brown, Bonnie L; Snutch, Terrance P; Olsen, Hugh E

2017-01-01

Long-read sequencing is rapidly evolving and reshaping the suite of opportunities for genomic analysis. For the MinION in particular, as both the platform and chemistry develop, the user community requires reference data to set performance expectations and maximally exploit third-generation sequencing. We performed an analysis of MinION data derived from whole genome sequencing of Escherichia coli K-12 using the R9.0 chemistry, comparing the results with the older R7.3 chemistry. We computed the error-rate estimates for insertions, deletions, and mismatches in MinION reads. Run-time characteristics of the flow cell and run scripts for R9.0 were similar to those observed for R7.3 chemistry, but with an 8-fold increase in bases per second (from 30 bps in R7.3 and SQK-MAP005 library preparation, to 250 bps in R9.0) processed by individual nanopores, and less drop-off in yield over time. The 2-dimensional ("2D") N50 read length was unchanged from the prior chemistry. Using the proportion of alignable reads as a measure of base-call accuracy, 99.9% of "pass" template reads from 1-dimensional ("1D")  experiments were mappable and ~97% from 2D experiments. The median identity of reads was ~89% for 1D and ~94% for 2D experiments. The total error rate (miscall + insertion + deletion ) decreased for 2D "pass" reads from 9.1% in R7.3 to 7.5% in R9.0 and for template "pass" reads from 26.7% in R7.3 to 14.5% in R9.0. These Phase 2 MinION experiments serve as a baseline by providing estimates for read quality, throughput, and mappability. The datasets further enable the development of bioinformatic tools tailored to the new R9.0 chemistry and the design of novel biological applications for this technology. K: thousand, Kb: kilobase (one thousand base pairs), M: million, Mb: megabase (one million base pairs), Gb: gigabase (one billion base pairs).

Characteristics of surface acoustic waves in (11\\bar 2 0)ZnO film/ R-sapphire substrate structures

Science.gov (United States)

Wang, Yan; Zhang, ShuYi; Xu, Jing; Xie, YingCai; Lan, XiaoDong

2018-02-01

(11\\bar 2 0)ZnO film/ R-sapphire substrate structure is promising for high frequency acoustic wave devices. The propagation characteristics of SAWs, including the Rayleigh waves along [0001] direction and Love waves along [1ī00] direction, are investigated by using 3 dimensional finite element method (3D-FEM). The phase velocity ( v p), electromechanical coupling coefficient ( k 2), temperature coefficient of frequency ( TCF) and reflection coefficient ( r) of Rayleigh wave and Love wave devices are theoretically analyzed. Furthermore, the influences of ZnO films with different crystal orientation on SAW properties are also investigated. The results show that the 1st Rayleigh wave has an exceedingly large k 2 of 4.95% in (90°, 90°, 0°) (11\\bar 2 0)ZnO film/ R-sapphire substrate associated with a phase velocity of 5300 m/s; and the 0th Love wave in (0°, 90°, 0°) (11\\bar 2 0)ZnO film/ R-sapphire substrate has a maximum k 2 of 3.86% associated with a phase velocity of 3400 m/s. And (11\\bar 2 0)ZnO film/ R-sapphire substrate structures can be used to design temperature-compensated and wide-band SAW devices. All of the results indicate that the performances of SAW devices can be optimized by suitably selecting ZnO films with different thickness and crystal orientations deposited on R-sapphire substrates.

R0-modeling as a tool for early warning and surveillance of exotic vector borne diseases in Denmark

DEFF Research Database (Denmark)

Bødker, Rene; Kristensen, Birgit; Græsbøll, Kaare

2011-01-01

local spread of exotic insect borne diseases of veterinary and human importance. R0 models for various vector borne diseases are continuously updated with spatial temperature data to quantify the present risk of autochthonous cases (R0>0) and the present risk of epidemics (R0>1) in case an infected...... surveillance to these limited periods of potential risk, thus dramatically reducing the number of samples collected and analysed. The risk estimated from the R0 modelling may be combined with the risk of introduction from neighbouring countries and trading partners to generate a truly risk based surveillance......Modelling the potential transmission intensity of insect borne diseases with climate driven R0 process models is frequently used to assess the potential for veterinary and human infections to become established in non endemic areas. Models are often based on mean temperatures of an arbitrary time...

Certified reference materials for radionuclides in Bikini Atoll sediment (IAEA-410) and Pacific Ocean sediment (IAEA-412)

DEFF Research Database (Denmark)

Pham, M. K.; van Beek, P.; Carvalho, F. P.

2016-01-01

The preparation and characterization of certified reference materials (CRMs) for radionuclide content in sediments collected offshore of Bikini Atoll (IAEA-410) and in the open northwest Pacific Ocean (IAEA-412) are described and the results of the certification process are presented. The certified...... radionuclides include: 40K, 210Pb (210Po), 226Ra, 228Ra, 228Th, 232Th, 234U, 238U, 239Pu, 239+240Pu and 241Am for IAEA-410 and 40K, 137Cs, 210Pb (210Po), 226Ra, 228Ra, 228Th, 232Th, 235U, 238U, 239Pu, 240Pu and 239+240Pu for IAEA-412. The CRMs can be used for quality assurance and quality control purposes...

Assessing the Biohazard Potential of Putative Martian Organisms for Exploration Class Human Space Missions

Science.gov (United States)

Warmflash, David; Larios-Sanz, Maia; Jones, Jeffrey; Fox, George E.; McKay, David S.

2007-01-01

Exploration Class missions to Mars will require precautions against potential contamination by any native microorganisms that may be incidentally pathogenic to humans. While the results of NASA's Viking biology experiments of 1976 have been generally interpreted as inconclusive for surface organisms, the possibility of native surface life has never been ruled out and more recent studies suggest that the case for biological interpretation of the Viking Labeled Release data may now be stronger than it was when the experiments were originally conducted. It is possible that, prior to the first human landing on Mars, robotic craft and sample return missions will provide enough data to know with certainty whether or not future human landing sites harbor extant life forms. However, if native life is confirmed, it will be problematic to determine whether any of its species may present a medical risk to astronauts. Therefore, it will become necessary to assess empirically the risk that the planet contains pathogens based on terrestrial examples of pathogenicity and to take a reasonably cautious approach to bio-hazard protection. A survey of terrestrial pathogens was conducted with special emphasis on those pathogens whose evolution has not depended on the presence of animal hosts. The history of the development and implementation of Apollo anticontamination protocol and recent recommendations of the NRC Space Studies Board regarding Mars were reviewed. Organisms can emerge in nature in the absence of indigenous animal hosts and both infectious and non-infectious human pathogens are theoretically possible on Mars. The prospect of Martian surface life, together with the existence of a diversity of routes by which pathogenicity has emerged on Earth, suggests that the possibility of human pathogens on Mars, while low, is not zero. Since the discovery and study of Martian life can have long-term benefits for humanity, the risk that Martian life might include pathogens should not

Luminescence and magnetic properties of novel nanoparticle-sheathed 3D Micro-Architectures of Fe0.5R0.5(MoO4)1.5:Ln3+ (R = Gd3+, La3+), (Ln = Eu, Tb, Dy) for bifunctional application

Science.gov (United States)

Krishnan, Rajagopalan; Thirumalai, Jagannathan; Kathiravan, Arunkumar

2015-01-01

For the first time, we report the successful synthesis of novel nanoparticle-sheathed bipyramid-like and almond-like Fe0.5R0.5(MoO4)1.5:Ln3+ (R = Gd3+, La3+), (Ln = Eu, Tb, Dy) 3D hierarchical microstructures through a simple disodium ethylenediaminetetraacetic acid (Na2EDTA) facilitated hydrothermal method. Interestingly, time-dependent experiments confirm that the assembly-disassembly process is responsible for the formation of self-aggregated 3D architectures via Ostwald ripening phenomena. The resultant products are characterized by x-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM), photoluminescence (PL), and magnetic measurements. The growth and formation mechanisms of the self-assembled 3D micro structures are discussed in detail. To confirm the presence of all the elements in the microstructure, the energy loss induced by the K, L shell electron ionization is observed in order to map the Fe, Gd, Mo, O, and Eu components. The photo luminescence properties of Fe0.5R0.5(MoO4)1.5 doped with Eu3+, Tb3+, Dy3+ are investigated. The room temperature and low temperature magnetic properties suggest that the interaction between the local-fields introduced by the magnetic Fe3+ ions and the R3+ (La, Gd) ions in the dodecahedral sites determine the magnetism in Fe0.5R0.5(MoO4)1.5:Eu3+. This work provides a new approach to synthesizing the novel Fe0.5R0.5(MoO4)1.5:Ln3+ for bi-functional magnetic and luminescence applications.

A Measurement of the Branching Ratio R(B) = Gamma (Z(0) --> B Anti-B)/Gamma (Z(0) --> Hadrons) Using a Minimum Missing P(T) Corrected Mass Tag

Energy Technology Data Exchange (ETDEWEB)

Weiss, E

2003-12-18

Presented here is a new measurement of R{sub b} = {Lambda}(Z{sup 0} {yields} b{bar b})/{Lambda}(Z{sup 0} {yields} hadrons) using a self-calibrating double tag technique where the b selection is based on topological and kinematic reconstruction of the mass of the B-decay vertex. The measurement was performed using a sample of 72074 hadronic Z{sup 0} events out of the 150 k hadronic Z{sup 0} decays collected with the SLD at the SLAC Linear Collider during 1993-1995. The method utilizes the 3-D vertexing abilities of the SLD CCD pixel vertex detector and the small stable SLC beams to obtain a high b tagging efficiency of 35.3% for a purity of 98.0%. The high purity reduces the systematic uncertainty introduced by charm contamination and correlations with R{sub c}. They obtain a result of R{sub b} = 0.2142 {+-} 0.0034{sub stat.} {+-} 0.0015{sub syst.} {+-} 0.0002{sub R{sub b}} (corrected for the e{sup +}e{sup -} {yields} {gamma} exchange contribution).

Simulated versus realistic intra operative radiation therapy (I.O.R.T.) treatment in operating room: from knowledge of stray radiation to action

International Nuclear Information System (INIS)

Andreoli, S.; Moretti, R.; Catalano, M.; Locatelli, F.

2006-01-01

Intra-Operative Radiation Therapy (I.O.R.T.) is carried out with electron beams produced by a Linac (Linear Accelerator) generally used for conventional radiotherapy with external beam, or by dedicated accelerators that can be employed directly into an operating room. I.O.R.T. refers to the application of radiation during a surgical intervention, after the removal of a neoplastic mass. I.O.R.T. uses on the tumour area a direct irradiation, for the possible localisation of sub-clinic illness or macroscopic residue in the case of non-radical resection. Intra-Operative Radiotherapy foresees a single session only, generally preceded or followed by radiotherapy with external beam. It allows the achievement of a selective radiation boost on the tumour volume. In some cases, it can also be used as a one-time/stand alone treatment in initial cancer of small volume, or in unresectable malignancies for palliative purpose. The technical advantages of I.O.R.T. consist in the direct visual control of the target volume, and in the possibility to protect the healthy tissues by moving them away from the path of the radiation beam. The use of electron beams allows the administration of a homogeneous dose to a selected layer of tissues surrounding the tumour. The following professional staff forms the Operative Group: radiation oncologist, surgeon, anaesthetist, medical physicist, radiation technologist, nurse.The choice of a simulation geometry very similar to the clinical situation allows to evaluate radioprotection data very close to the real situation. For a fixed layout, an anthropomorphic phantom was positioned on the operating bed and a breast I.O.R.T. treatment was simulated positioning all the accessories of the operating room in their typical positions. A detailed dose mapping was performed with a Victoreen 450P ionisation chamber and with environment film-dosimeter on the walls of the operating room during the simulation of the clinical treatment. The simulation appears

Sensitivity and Specificity of Bioassay of Estrogenicity on Mammary Gland and Uterus of Female Mice

Czech Academy of Sciences Publication Activity Database

Škarda, Josef

2002-01-01

Roč. 51, - (2002), s. 407-412 ISSN 0862-8408 R&D Projects: GA ČR GA523/99/0843; GA AV ČR KSK5020115 Institutional research plan: CEZ:AV0Z5045916 Keywords : Bioassay * Estrogenicity * Mammary gland Subject RIV: ED - Physiology Impact factor: 0.984, year: 2002

Spectral Theory for Schrodinger Operators with delta-Interactions Supported on Curves in R-3

Czech Academy of Sciences Publication Activity Database

Behrndt, J.; Frank, R. L.; Kuhn, C.; Lotoreichik, Vladimir; Rohleder, J.

2017-01-01

Roč. 18, č. 4 (2017), s. 1305-1347 ISSN 1424-0637 R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : spectral theory * scattering theory * self-adjoint Schrodinger operators Subject RIV: BE - Theoretical Physics OBOR OECD: Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect) Impact factor: 1.599, year: 2016

Topotactic reduction and reoxidation of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} (R = Y, Eu-Lu) Phases

Energy Technology Data Exchange (ETDEWEB)

Jiang, Peng, E-mail: jiangp@onid.orst.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Berthelot, Romain, E-mail: berthelot.rom@gmail.com [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Li, Jun, E-mail: jli100@yahoo.com [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Sleight, A.W., E-mail: arthur.sleight@oregonstate.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Subramanian, M.A., E-mail: mas.subramanian@oregonstate.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States)

2013-06-01

Highlights: ► Topotactic reduction of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} phases is performed. ► TGA and magnetism indicate a formula of RCu{sub 0.5}Ti{sub 0.5}O{sub 2.78} for the reduced phase. ► Topotactic reoxidation occurs on heating these phases to 400 °C in air. - Abstract: Hexagonal AMO{sub 2} and AMO{sub 3} phases have the same basic structure, and intermediate compositions for this structure have been prepared by topotactic oxidation of AMO{sub 2} phases such as RCuO{sub 2}, where R is a trivalent rare earth cation. We now find that such intermediate phases can also be prepared by topotactic reduction of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} (R = Y, Tb-Lu) phases. Our TGA and magnetic susceptibility studies indicate a formula of RCu{sub 0.5}Ti{sub 0.5}O{sub 2.78} for these reduced phases. Topotactic reoxidation occurs on heating these phases to 400 °C in air.

IEA-R1 research reactor: operational life extension and considerations regarding future decommissioning

International Nuclear Information System (INIS)

Frajndlich, Roberto

2009-01-01

The IEA-R1 reactor is a pool type research reactor moderated and cooled by light water and uses graphite and beryllium reflectors. The reactor is located at the Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN/SP), in the city of Sao Paulo, Brazil. It is the oldest research reactor in the southern hemisphere and one of the oldest of this kind in the world. The first criticality of the reactor was obtained on September 16, 1957. Given the fact that Brazil does not have yet a definitive radioactive waste repository and a national policy establishing rules for the spent fuel storage, the institutions which operate the research reactors for more than 50 years in the country have searched internal solutions for continued operation. This paper describes the spent fuel assemblies and radioactive waste management process for the IEA-R1 reactor and the refurbishment and modernization program adopted to extend its lifetime. Some considerations about the future decommissioning of the reactor are also discussed which, in my opinion, might help the operating organization to make decisions about financial, legal and technical aspects of the decommissioning procedures in a time frame of 10-15 years(author)

42 CFR 412.210 - Puerto Rico rates for Federal fiscal years 1989 through 2003.

Science.gov (United States)

2010-10-01

...) Geographic classifications. (1) For purposes of this section, the definitions set forth in § 412.208(f)(1... of final standards for classification of MSAs published in the Federal Register on January 3, 1980... discharge classified within a DRG, CMS establishes for the fiscal year a Puerto Rico prospective payment...

Synthesis of carbasugars from aldonolactones, part III - A study on the allylic substitution of (1R,5R,8R)- and (1R,5R,8S)-8-hydroxy-2-oxabicyclo[3.3.0]oct-6-en-3-one derivatives - Preparation of (1S,2R,3R)-9-[2-hydroxy-3-(2-hydroxyethyl)cyclopent-4-en-1-yl]-9H-adenine

DEFF Research Database (Denmark)

Johansen, Steen Karsk; Lundt, Inge

2001-01-01

The palladium-catalyzed substitution of acylated (1R,5R,8R)- and (1R,SR,8S)-8-hydroxy-2-oxabicyclo[3.3.0] ones has been studied using a number of C- and N-nucleophiles, In all cases, the exo derivatives (8R) were found to be more reactive than the corresponding endo derivatives (8S). The reaction...... with these nucleophiles. Additionally, Mitsunobu substitution of (1R,5R,8R)-8-hydroxy-2-oxabicyclo[3.3.0]oct-B-en-3-one (3) with 6-chloropurine, followed by reduction of the lactone moiety and treatment with Liquid ammonia, gave the carbocyclic nucleoside (1S,2R,3R)-9-[2-hydroxy-3-(2-hydroxyethyl)cyclopent-4-en-1-yl]-9H...

Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators.

Science.gov (United States)

Lie, Thomas J; Wood, Gwendolyn E; Leigh, John A

2005-02-18

The methanogenic archaean Methanococcus maripaludis can use ammonia, alanine, or dinitrogen as a nitrogen source for growth. The euryarchaeal nitrogen repressor NrpR controls the expression of the nif (nitrogen fixation) operon, resulting in full repression with ammonia, intermediate repression with alanine, and derepression with dinitrogen. NrpR binds to two tandem operators in the nif promoter region, nifOR(1) and nifOR(2). Here we have undertaken both in vivo and in vitro approaches to study the way in which NrpR, nifOR(1), nifOR(2), and the effector 2-oxoglutarate (2OG) combine to regulate nif expression, leading to a comprehensive understanding of this archaeal regulatory system. We show that NrpR binds as a dimer to nifOR(1) and cooperatively as two dimers to both operators. Cooperative binding occurs only with both operators present. nifOR(1) has stronger binding and by itself can mediate the repression of nif transcription during growth on ammonia, unlike the weakly binding nifOR(2). However, nifOR(2) in combination with nifOR(1) is critical for intermediate repression during growth on alanine. Accordingly, NrpR binds to both operators together with higher affinity than to nifOR(1) alone. NrpR responds directly to 2OG, which weakens its binding to the operators. Hence, 2OG is an intracellular indicator of nitrogen deficiency and acts as an inducer of nif transcription via NrpR. This model is upheld by the recent finding (J. A. Dodsworth and J. A. Leigh, submitted for publication) in our laboratory that 2OG levels in M. maripaludis vary with growth on different nitrogen sources.

Neutron diffraction study of a nitrogen martensitic steel 0Kh16N4AB under load

Czech Academy of Sciences Publication Activity Database

Sumin, V. V.; Papushkin, I.V.; Bannykh, O.A.; Blinov, V.M.; Lukáš, Petr

2008-01-01

Roč. 105, č. 1 (2008), s. 88-91 ISSN 0031-918X Institutional research plan: CEZ:AV0Z10480505 Keywords : steel 0Kh16N4AB * neutron diffraction * FSD Subject RIV: BG - Nuclear, Atomic and Molecular Physics , Colliders Impact factor: 0.412, year: 2008

Adsorption of Procion Blue MX-R dye from aqueous solutions by lignin chemically modified with aluminium and manganese

Energy Technology Data Exchange (ETDEWEB)

Adebayo, Matthew A. [Institute of Chemistry, Federal University of Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9500, Postal Box 15003, 91501-970 Porto Alegre, RS (Brazil); Department of Chemical Sciences, Ajayi Crowther University, PMB 1066 Oyo, Oyo State (Nigeria); Prola, Lizie D.T. [Institute of Chemistry, Federal University of Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9500, Postal Box 15003, 91501-970 Porto Alegre, RS (Brazil); Lima, Eder C., E-mail: eder.lima@ufrgs.br [Institute of Chemistry, Federal University of Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9500, Postal Box 15003, 91501-970 Porto Alegre, RS (Brazil); Puchana-Rosero, M.J.; Cataluña, Renato; Saucier, Caroline; Umpierres, Cibele S.; Vaghetti, Julio C.P. [Institute of Chemistry, Federal University of Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9500, Postal Box 15003, 91501-970 Porto Alegre, RS (Brazil); Silva, Leandro G. da; Ruggiero, Reinaldo [Institute of Chemistry, Federal University of Uberlândia (UFU), AV. João Naves de Ávila 2121 block 1D—Campus Santa Mônica, 38400-902 Uberlândia, MG (Brazil)

2014-03-01

Graphical abstract: - Highlights: • Complexes of carboxy-methylated lignin with Al and Mn were used as adsorbents. • The optimum adsorption conditions were achieved at pH 2 and 298 K. • Maximum adsorption capacities are 73.52 mg g{sup −1} (CML-Al) and 55.16 mg g{sup −1} (CML-Mn). • CML-Al could remove ca. 95.83% of dye-contaminated industrial effluents. • CML-Al and CML-Mn are effective for treatment of simulated dye-house effluents. - Abstract: A macromolecule, CML, was obtained by purifying and carboxy-methylating the lignin generated from acid hydrolysis of sugarcane bagasse during bioethanol production from biomass. The CMLs complexed with Al{sup 3+} (CML-Al) and Mn{sup 2+} (CML-Mn) were utilised for the removal of a textile dye, Procion Blue MX-R (PB), from aqueous solutions. CML-Al and CML-Mn were characterised using Fourier transform infrared spectroscopy (FTIR), scanning differential calorimetry (SDC), scanning electron microscopy (SEM) and pH{sub PZC}. The established optimum pH and contact time were 2.0 and 5 h, respectively. The kinetic and equilibrium data fit into the general order kinetic model and Liu isotherm model, respectively. The CML-Al and CML-Mn have respective values of maximum adsorption capacities of 73.52 and 55.16 mg g{sup −1} at 298 K. Four cycles of adsorption/desorption experiments were performed attaining regenerations of up to 98.33% (CML-Al) and 98.08% (CML-Mn) from dye-loaded adsorbents, using 50% acetone + 50% of 0.05 mol L{sup −1} NaOH. The CML-Al removed ca. 93.97% while CML-Mn removed ca. 75.91% of simulated dye house effluents.

Combined robotic transanal total mesorectal excision (R-taTME) and single-site plus one-port (R-SSPO) technique for ultra-low rectal surgery-initial experience with a new operation approach.

Science.gov (United States)

Kuo, Li-Jen; Ngu, James Chi-Yong; Tong, Yiu-Shun; Chen, Chia-Che

2017-02-01

Robot-assisted rectal surgery is gaining popularity, and robotic single-site surgery is also being explored clinically. We report our initial experience with robotic transanal total mesorectal excision (R-taTME) and radical proctectomy using the robotic single-site plus one-port (R-SSPO) technique for low rectal surgery. Between July 2015 and March 2016, 15 consecutive patients with ultra-low rectal lesions underwent R-taTME followed by radical proctectomy using the R-SSPO technique by a single surgeon. The clinical and pathological results were retrospectively analyzed. The median operative time was 473 (range, 335-569) min, and the estimated blood loss was 33 (range, 30-50) mL. The median number of lymph nodes harvested was 12 (range, 8-18). The median distal resection margin was 1.4 (range, 0.4-3.5) cm, and all patients had clear circumferential resection margins. We encountered a left ureteric transection intraoperatively in one patient, and another patient required reoperation for postoperative adhesive intestinal obstruction. There was no 30-day mortality. R-taTME followed by radical proctectomy using the R-SSPO technique for patients with low rectal lesions is technically feasible and safe without compromising oncologic outcomes. However, there were considerable limitations and a steep learning curve using current robotic technology.

The R and D/operational MC and A [materials control and accounting] interface

International Nuclear Information System (INIS)

Shipley, J.P.

1987-06-01

Improvements in our ability to do materials control and accounting (MC and A) have been steady since the beginning of the nuclear age and the appearance of processes and facilities for handling nuclear materials. The motivation for these improvements has not been just safeguards: the desire for better process control also has played a major role, and the emergence of technology focused on the problems of MC and A has made it possible to pursue such improvements. However, it is a continuing challenge to match the needs of the operational MC and A elements with the capabilities and resources of the R and D community. In the last couple of years this challenge has been addressed very visibly by the DOE's Project Cerberus R and D Committee, which has devised a procedure to encourage closer interactions between the operations and R and D elements. In the particular case of Los Alamos, we have recently concluded the efforts of the Nuclear Materials Management and Safeguards Task Force, which made strong recommendations about the need for close internal cooperation. The issues associated with these activities and the specific means for addressing them, will be of surpassing interest for the future of safeguards

Vector-borne diseases: the basic reproduction number R0 and risk maps

NARCIS (Netherlands)

Hartemink, N.A.|info:eu-repo/dai/nl/304836699

2009-01-01

This thesis deals with the derivation of the basic reproduction number (R0) for vector-borne diseases, in the context of studying the effect of climate change on the risk of emergence diseases. Vector-borne diseases are transmitted from an infected individual to another individual by vectors,

Development of a training simulator to operators of the IEA-R1 research reactor

International Nuclear Information System (INIS)

Carvalho, Ricardo Pinto de

2006-01-01

This work reports the development of a Simulator for the IEA-R1 Research Reactor. The Simulator was developed with Visual C++ in two stages: construction of the mathematics models and development and configuration of graphics interfaces in a Windows XP executable. A simplified modeling was used for main physics phenomena, using a point kinetics model for the nuclear process and the energy and mass conservation laws in the average channel of the reactor for the thermal hydraulic process. The dynamics differential equations were solved by using finite differences through the 4th order Runge- Kutta method. The reactivity control, reactor cooling, and reactor protection systems were also modeled. The process variables are stored in ASCII files. The Simulator allows navigating by screens of the systems and monitoring tendencies of the operational transients, being an interactive tool for teaching and training of IEA-R1 operators. It also can be used by students, professors, and researchers in teaching activities in reactor and thermal hydraulics theory. The Simulator allows simulations of operations of start up, power maneuver, and shut down. (author)

Operation characteristic of a R123-based organic Rankine cycle depending on working fluid mass flow rates and heat source temperatures

International Nuclear Information System (INIS)

Feng, Yong-Qiang; Hung, Tzu-Chen; Wu, Shang-Lun; Lin, Chih-Hung; Li, Bing-Xi; Huang, Kuo-Chen; Qin, Jiang

2017-01-01

Highlights: • The operation characteristic of an Organic Rankine Cycle using R123 and a scroll expander have been investigated. • The behaviors and detailed discussion for those four major components are examined. • The expander isentropic efficiency presents a slight decrease first and then a sharp increase with mass flow rate. • The maximum electrical power and system generation efficiency are 2.01 kW and 3.25%, respectively. - Abstract: The test and operation characteristic of an organic Rankine cycle using R123 and a scroll expander have been investigated. The steady-state operation characteristic is addressed with the varying working fluid mass flow rates ranging of 0.124–0.222 kg/s and heat source temperatures ranging of 383.15–413.15 K. The behaviors and detailed discussion for those four major components (pump, evaporator, expander and condenser) are examined. The experimental results show that the environmental temperature presents a higher influence on the pump behaviors. The range of pump power consumption, isentropic efficiency and back work ratio are 0.21–0.32 kW, 26.76–53.96%, and 14–32%, respectively. The expander isentropic efficiency presents a slight decrease first and then a sharp increase with mass flow rate, while a degree of superheating more than 3 K is necessary to avoid expander cavitation. The expander isentropic and generator efficiencies are in range of 69.10–85.17% and 60–73%, respectively, while the respective heat transfer coefficients for evaporator and condenser are ranging of 200–400 and 450–2000 W/m"2 K. The maximum expander shaft power and electrical power are 2.78 kW and 2.01 kW, respectively, while the maximum system generating efficiency is 3.25%. Moreover, the tested thermal efficiency presents a slight decrease trend with mass flow rate.

Utilization of flue gas for cultivation of microalgae (Chlorella sp.) in an outdoor open thin-layer photobioreactor

Czech Academy of Sciences Publication Activity Database

Doucha, Jiří; Straka, F.; Lívanský, Karel

2005-01-01

Roč. 17, - (2005), s. 403-412 ISSN 0921-8971 R&D Projects: GA ČR GV104/97/S055; GA ČR GA104/02/0410 Institutional research plan: CEZ:AV0Z50200510 Keywords : microalgae * flue gas * carbon dioxide Subject RIV: EE - Microbiology, Virology Impact factor: 0.992, year: 2005

Operation Iraqi Freedom 06-08: Iraq. Operation Enduring Freedom 8: Afghanistan

Science.gov (United States)

2008-02-14

Optimizing Theater Assets 15.6.3 Addressing Reported Short 15.6.4 Leadership and R 15.6.5 Sleep Managemen 15.6.6 Results Related t 15.6.7 NCOs and...36.4% 32.0% 0.02 Continuous operations . 38.8% 33.3% 000 Long deployment length. 57.1% 57.1% 0.99 6.2.2 Top Concerns in MHA T V While the...IT0 and are experienced using AHLTA- T . As noted above, as the operational theater matures in Iraq, there is a clear push to use EMR reporting

Hematological and immunological parameters of 4-1/2-month-old pigs infected with PRRS virus

DEFF Research Database (Denmark)

Nielsen, Jens; Bøtner, Anette

1997-01-01

4-1/2-month old SPF pigs were experimentally infected with PRRS virus. Blood samples were collected with regular intervals up to day 35 post inoculation (PI). Serum was used for PRRS virus isolation and antibody detection and stabilized blood for total leucocyte counts, differential counts and ch...

29 CFR 2580.412-19 - Term of the bond, discovery period, other bond clauses.

Science.gov (United States)

2010-07-01

... SECURITY ACT OF 1974 TEMPORARY BONDING RULES General Bond Rules § 2580.412-19 Term of the bond, discovery... 29 Labor 9 2010-07-01 2010-07-01 false Term of the bond, discovery period, other bond clauses... new bond must be obtained each year. There is nothing in the Act that prohibits a bond for a term...

Optical and structural study of BST multilayers

Czech Academy of Sciences Publication Activity Database

Železný, Vladimír; Chvostová, Dagmar; Pajasová, Libuše; Jelínek, Miroslav; Kocourek, Tomáš; Daniš, S.; Valvoda, V.

2010-01-01

Roč. 12, č. 3 (2010), 538-541 ISSN 1454-4164 R&D Projects: GA ČR GA202/07/0591 Institutional research plan: CEZ:AV0Z10100522; CEZ:AV0Z10100520 Keywords : ellipsometry * structure * ferroelectric multilayers Subject RIV: BH - Optics, Masers, Lasers Impact factor: 0.412, year: 2010

Circulating miR-126 and miR-499 reflect progression of cardiovascular disease; correlations with uric acid and ejection fraction

Directory of Open Access Journals (Sweden)

Masoud Khanaghaei

2016-04-01

Full Text Available BackgroundThe aim of this study was to assess plasma levels of endothelium- and heart-associated microRNAs (miRNAs miR-126 and miR-499, respectively, using quantitative reverse transcriptase polymerase chain reaction.MethodsA two-step analysis was conducted on 75 patients undergoing off-pomp coronary artery bypass graft (CABG surgery. Five biomarkers of inflammation and cardiac injury were assessed in addition to the above-mentioned miRNAs.ResultsPlasma concentrations of miRNAs were found to be significantly correlated with plasma levels of cardiac troponin I (cTnI (miR-499, r 0.49, p~0.002; miR-126, r = 0.30, p~0.001, indicating cardiac damage. Data analysis revealed that miR-499 had higher sensitivity and specificity for cardiac injury than miR-126, which reflects more endothelial activation. Interestingly, a strong correlation was observed between both miRNAs and uric acid (UA levels with ventricular contractility measured as ejection fraction (EF (miR-499/EF%, r = 0.58, p~0.004; UA/EF%, r = -0.6, p~0.006; UA/miR-499, r = -0.34; UA/miR-126, r = 0.5, p~0.01.ConclusionsIn patients undergoing CABG, circulating miR-126/499 is associated with presentation of traditional risk factors and reflects post-operative response to injury. Plasma pool of miRNAs likely reflects extracellular miRNAs which are proportional to intracellular miRNA levels. Therefore, circulating levels of these miRNAs have prognostic implications in detection of higher risk of future cardiovascular events.

FINAL REPORT SUMMARY OF DM 1200 OPERATION AT VSL VSL-06R6710-2 REV 0 9/7/06

Energy Technology Data Exchange (ETDEWEB)

KRUGER AA; MATLACK KS; DIENER G; BARDAKCI T; PEGG IL

2011-12-29

The principal objective of this report was to summarize the testing experience on the DuraMelter 1200 (DMI200), which is the High Level Waste (HLW) Pilot Melter located at the Vitreous State Laboratory (VSL). Further objectives were to provide descriptions of the history of all modifications and maintenance, methods of operation, problems and unit failures, and melter emissions and performance while processing a variety of simulated HL W and low activity waste (LAW) feeds for the Hanford Waste Treatment and Immobilization Plant (WTP) and employing a variety of operating methods. All of these objectives were met. The River Protection Project - Hanford Waste Treatment and Immobilization Plant (RPP-WTP) Project has undertaken a 'tiered' approach to vitrification development testing involving computer-based glass formulation, glass property-composition models, crucible melts, and continuous melter tests of increasing, more realistic scales. Melter systems ranging from 0.02 to 1.2 m{sup 2} installed at the Vitreous State Laboratory (VSL) have been used for this purpose, which, in combination with the 3.3 m{sup 2} low activity waste (LAW) Pilot Melter at Duratek, Inc., span more than two orders of magnitude in melt surface area. In this way, less-costly small-scale tests can be used to define the most appropriate tests to be conducted at the larger scales in order to extract maximum benefit from the large-scale tests. For high level waste (HLW) vitrification development, a key component in this approach is the one-third scale DuraMelter 1200 (DM 1200), which is the HLW Pilot Melter that has been installed at VSL with an integrated prototypical off-gas treatment system. That system replaced the DM1000 system that was used for HLW throughput testing during Part B1. Both melters have similar melt surface areas (1.2 m{sup 2}) but the DM1200 is prototypical of the present RPP-WTP HLW melter design whereas the DM1000 was not. In particular, the DM1200 provides for

Final Report Summary Of DM 1200 Operation At VSL VSL-06R6710-2, Rev. 0, 9/7/06

International Nuclear Information System (INIS)

Kruger, A.A.; Matlack, K.S.; Diener, G.; Bardakci, T.; Pegg, I.L.

2011-01-01

The principal objective of this report was to summarize the testing experience on the DuraMelter 1200 (DMI200), which is the High Level Waste (HLW) Pilot Melter located at the Vitreous State Laboratory (VSL). Further objectives were to provide descriptions of the history of all modifications and maintenance, methods of operation, problems and unit failures, and melter emissions and performance while processing a variety of simulated HL W and low activity waste (LAW) feeds for the Hanford Waste Treatment and Immobilization Plant (WTP) and employing a variety of operating methods. All of these objectives were met. The River Protection Project - Hanford Waste Treatment and Immobilization Plant (RPP-WTP) Project has undertaken a 'tiered' approach to vitrification development testing involving computer-based glass formulation, glass property-composition models, crucible melts, and continuous melter tests of increasing, more realistic scales. Melter systems ranging from 0.02 to 1.2 m 2 installed at the Vitreous State Laboratory (VSL) have been used for this purpose, which, in combination with the 3.3 m 2 low activity waste (LAW) Pilot Melter at Duratek, Inc., span more than two orders of magnitude in melt surface area. In this way, less-costly small-scale tests can be used to define the most appropriate tests to be conducted at the larger scales in order to extract maximum benefit from the large-scale tests. For high level waste (HLW) vitrification development, a key component in this approach is the one-third scale DuraMelter 1200 (DM 1200), which is the HLW Pilot Melter that has been installed at VSL with an integrated prototypical off-gas treatment system. That system replaced the DM1000 system that was used for HLW throughput testing during Part B1. Both melters have similar melt surface areas (1.2 m 2 ) but the DM1200 is prototypical of the present RPP-WTP HLW melter design whereas the DM1000 was not. In particular, the DM1200 provides for testing on a vitrification

Phase competition by design in R0.5Ba0.5MnO3

Science.gov (United States)

Nowadnick, Elizabeth; He, Jiangang; Fennie, Craig

Phase competition between distinct ground states can arise from interactions on similar energy scales between the spin, charge, lattice, and orbital degrees of freedom. This competition can result in large responses to external perturbations. For example, the colossal magnetoresistance effect in the rare-earth manganites R1-xAxMnO3 arises out of competing ferromagnetic metallic and charge/orbital-ordered antiferromagnetic insulating states. Phase competition between polar and magnetic ground states is a promising strategy to realize polarization (magnetization) control with a magnetic (electric) field, which is major goal in multiferroics research. In this regard, the half-doped A-site ordered manganite Sm0.5Ba0.5MnO3 is of particular interest, because the charge/orbital-ordered antiferromagnetic insulating state in this material is polar. We use a combination of group theoretic methods and first-principles calculations to elucidate the origin of this polar state, and show that epitaxial strain can tune the material to a regime where there is a strong competition between the polar insulating state and the ferromagnetic metallic state. We then explore how to achieve electric and magnetic field control of the order parameters in this system.

Teaching Students with Developmental Disabilities to Operate an iPod Touch[R] to Listen to Music

Science.gov (United States)

Kagohara, Debora M.; Sigafoos, Jeff; Achmadi, Donna; van der Meer, Larah; O'Reilly, Mark F.; Lancioni, Giulio E.

2011-01-01

We evaluated an intervention procedure for teaching three students with developmental disabilities to independently operate a portable multimedia device (i.e., an iPod Touch[R]) to listen to music. The intervention procedure included the use of video modeling, which was presented on the same iPod Touch[R] that the students were taught to operate…

Thermal expansion of phosphates with the NaZr2(PO4)3 structure containing lanthanides and zirconium: R0.33Zr2(PO4)3 (R = Nd, Eu, Er) and Er0.33(1–x) Zr0.25xZr2(PO4)3

International Nuclear Information System (INIS)

Volgutov, V. Yu.; Orlova, A. I.

2015-01-01

Phosphates R 0.33 Zr 2 (PO 4 ) 3 (R = Nd, Eu, or Er) and Er 0.33(1–x) Zr 0.25 Zr 2 (PO 4 ) 3 (x = 0, 0.25, 0.5, 0.75, 1.0) of the NaZr 2 (PO 4 ) 3 family have been synthesized and investigated by high-temperature X-ray diffraction. The crystallochemical approach is used to obtain compounds with expected small and controllable thermal-expansion parameters. Phosphates with close-to-zero thermal-expansion parameters, including those with low thermal-expansion anisotropy, have been obtained: Nd 0.33 Zr 2 (PO 4 ) 3 with α a =–2.21 × 10 −6 °C −1 , α c = 0.81 × 10 −6 °C −1 , and Δα = 3.02 × 10 −6 °C –1 and Er 0.08 Zr 0.19 Zr 2 (PO 4 ) 3 with α a =–1.86 × 10 −6 °C −1 , α c = 1.73 × 10 −6 °C −1 , and Δα = 3.58 × 10 −6 °C −1

Dissolved Organic Carbon along the Louisiana coast from MODIS and MERIS satellite data

Science.gov (United States)

Chaichi Tehrani, N.; D'Sa, E. J.

2012-12-01

Dissolved organic carbon (DOC) plays a critical role in the coastal and ocean carbon cycle. Hence, it is important to monitor and investigate its the distribution and fate in coastal waters. Since DOC cannot be measured directly through satellite remote sensors, chromophoric dissolved organic matter (CDOM) as an optically active fraction of DOC can be used as an alternative proxy to trace DOC concentrations. Here, satellite ocean color data from MODIS, MERIS, and field measurements of CDOM and DOC were used to develop and assess CDOM and DOC ocean color algorithms for coastal waters. To develop a CDOM retrieval algorithm, empirical relationships between CDOM absorption coefficient at 412 nm (aCDOM(412)) and reflectance ratios Rrs(488)/Rrs(555) for MODIS and Rrs(510)/Rrs(560) for MERIS were established. The performance of two CDOM empirical algorithms were evaluated for retrieval of (aCDOM(412)) from MODIS and MERIS in the northern Gulf of Mexico. Further, empirical algorithms were developed to estimate DOC concentration using the relationship between in situ aCDOM(412) and DOC, as well as using the newly developed CDOM empirical algorithms. Accordingly, our results revealed that DOC concentration was strongly correlated to aCDOM (412) for summer and spring-winter periods (r2 = 0.9 for both periods). Then, using the aCDOM(412)-Rrs and the aCDOM(412)-DOC relationships derived from field measurements, a relationship between DOC-Rrs was established for MODIS and MERIS data. The DOC empirical algorithms performed well as indicated by match-up comparisons between satellite estimates and field data (R2=0.52 and 0.58 for MODIS and MERIS for summer period, respectively). These algorithms were then used to examine DOC distribution along the Louisiana coast.

Crystallization and preliminary X-ray crystallographic analysis of the GluR0 ligand-binding core from Nostoc punctiforme

International Nuclear Information System (INIS)

Lee, Jun Hyuck; Park, Soo Jeong; Rho, Seong-Hwan; Im, Young Jun; Kim, Mun-Kyoung; Kang, Gil Bu; Eom, Soo Hyun

2005-01-01

The GluR0 ligand-binding core from N. punctiforme was expressed, purified and crystallized in the presence of l-glutamate. A diffraction data set was collected to a resolution of 2.1 Å. GluR0 from Nostoc punctiforme (NpGluR0) is a bacterial homologue of the ionotropic glutamate receptor. The ligand-binding core of NpGluR0 was crystallized at 294 K using the hanging-drop vapour-diffusion method. The l-glutamate-complexed crystal belongs to space group C222 1 , with unit-cell parameters a = 78.0, b = 145.1, c = 132.1 Å. The crystals contain three subunits in the asymmetric unit, with a V M value of 2.49 Å 3 Da −1 . The diffraction limit of the l-glutamate complex data set was 2.1 Å using synchrotron X-ray radiation at beamline BL-4A of the Pohang Accelerator Laboratory (Pohang, Korea)

Crystallization and preliminary X-ray crystallographic analysis of the GluR0 ligand-binding core from Nostoc punctiforme

Energy Technology Data Exchange (ETDEWEB)

Lee, Jun Hyuck; Park, Soo Jeong; Rho, Seong-Hwan; Im, Young Jun; Kim, Mun-Kyoung; Kang, Gil Bu; Eom, Soo Hyun, E-mail: eom@gist.ac.kr [Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500-712 (Korea, Republic of)

2005-11-01

The GluR0 ligand-binding core from N. punctiforme was expressed, purified and crystallized in the presence of l-glutamate. A diffraction data set was collected to a resolution of 2.1 Å. GluR0 from Nostoc punctiforme (NpGluR0) is a bacterial homologue of the ionotropic glutamate receptor. The ligand-binding core of NpGluR0 was crystallized at 294 K using the hanging-drop vapour-diffusion method. The l-glutamate-complexed crystal belongs to space group C222{sub 1}, with unit-cell parameters a = 78.0, b = 145.1, c = 132.1 Å. The crystals contain three subunits in the asymmetric unit, with a V{sub M} value of 2.49 Å{sup 3} Da{sup −1}. The diffraction limit of the l-glutamate complex data set was 2.1 Å using synchrotron X-ray radiation at beamline BL-4A of the Pohang Accelerator Laboratory (Pohang, Korea)

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients.

Science.gov (United States)

Meng, Xiaodan; Joosse, Simon A; Müller, Volkmar; Trillsch, Fabian; Milde-Langosch, Karin; Mahner, Sven; Geffken, Maria; Pantel, Klaus; Schwarzenbach, Heidi

2015-11-03

Owing to late diagnosis in advanced disease stages, prognosis of patients with epithelial ovarian cancer (EOC) is poor. The quantification of deregulated levels of microRNAs could facilitate earlier diagnosis and improve prognosis of EOC. Seven microRNAs (miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429) were quantified in the serum of 180 EOC patients and 66 healthy women by TaqMan PCR microRNA assays. Median follow-up time was 21 months. The effects of miR-7 and miR-429 on apoptosis, cell proliferation, migration and invasion were investigated in two (EOC) cell lines. Serum levels of miR-25 (P=0.0001) and miR-93 (P=0.0001) were downregulated, whereas those of miR-7 (P=0.001) and miR-429 (P=0.0001) were upregulated in EOC patients compared with healthy women. The four microRNAs discriminated EOC patients from healthy women with a sensitivity of 93% and a specificity of 92%. The levels of miR-429 positively correlated with CA125 values (P=0.0001) and differed between FIGO I-II and III-IV stages (P=0.001). MiR-429 was an independent predictor of overall survival (P=0.011). Overexpressed miR-429 in SKOV3 cells led to suppression of cell migration (P=0.037) and invasion (P=0.011). Increased levels of miR-7 were associated with lymph node metastases (P=0.0001) and FIGO stages III-IV (P=0.0001). Overexpressed miR-7 in SKOV3 cells resulted in increased cell migration (P=0.001) and invasion (P=0.011). Additionally, the increased levels of miR-376a correlated with FIGO stages III-IV (P=0.02). Our data indicate the diagnostic potential of miR-7, miR-25, miR-93 and miR-429 in EOC and the prognostic potential of miR-429. This microRNA panel may be promising molecules to be targeted in the treatment of EOC.

Laser Remote Sensing and Photoacoustic Spectrometry Applied in Air Pollution Investigation

Czech Academy of Sciences Publication Activity Database

Zelinger, Zdeněk; Střižík, M.; Kubát, Pavel; Jaňour, Zbyněk; Berger, P.; Černý, A.; Engst, P.

2004-01-01

Roč. 42, - (2004), s. 403-412 ISSN 0143-8166 R&D Projects: GA AV ČR IAA3040101; GA ČR GA205/02/0898; GA MŠk OC 723.002 Institutional research plan: CEZ:AV0Z4040901 Keywords : DIAL * air pollution * laser photoacoustic spectroscopy Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.935, year: 2004

Effect of Gum Chewing on Intestinal Functions after Gynecological Operations: A Randomized Controlled Study

Directory of Open Access Journals (Sweden)

Taylan Şenol

2016-12-01

RESULTS: There was no difference between groups in terms of age, duration of operation, intraoperative blood loss, pre and postoperative serum hemoglobin levels, duration to first bowel sound, flatulence and defecation (p>0.05. Age (r=0.234, p=0.032, type of incision (r=0.228, p=0.037 were significantly correlated with the time to first bowel sound. Type of incision (r=0.295, p=0.006, duration of operation (r=0.277, p=0.01 and intraoperative blood loss (r=0.298, p=0.006 were significantly correlated with the time to first flatulence. In multivariate regression analyses, none of the variables were found to be significant parameter for time to first bowel sound (p>0.05. CONCLUSION: Gum chewing does not affect some of the gastrointestinal functions after gynecological operations and there is no single parameter for time to first bowel sound, first flatulence and first defecation, individual surgical and medical condition differences should be kept in mind while evaluating intestinal functions.

Influence of thickness on properties of YbxCo4Sb12 layers prepared by laser ablation

Czech Academy of Sciences Publication Activity Database

Zeipl, Radek; Jelínek, M.; Kocourek, Tomáš; Navrátil, Jiří; Yatskiv, Roman; Josieková, M.; Leshkov, Sergey; Jurek, Karel; Walachová, Jarmila

2010-01-01

Roč. 12, č. 3 (2010), s. 572-575 ISSN 1454-4164 R&D Projects: GA ČR GA203/07/0267 Institutional research plan: CEZ:AV0Z20670512; CEZ:AV0Z40500505; CEZ:AV0Z10100521 Keywords : thermoelectrics * thin layers * skutterudites Subject RIV: JA - Electronics ; Optoelectronics , Electrical Engineering Impact factor: 0.412, year: 2010

AIS ASM Operational Integration Plan

Science.gov (United States)

2013-08-01

Rack mount computer AIS Radio Interface Ethernet Switch 192.168.0.x Firewall Cable Modem 192.168.0.1 VTS Accred. Boundary AIS ASM Operational... AIS ASM Operational Integration Plan Distribution Statement A: Approved for public release; distribution is unlimited. August 2013 Report No...CD-D-07-15 AIS ASM Operational Integration Plan ii UNCLAS//Public | CG-926 R&DC | I. Gonin, et al. | Public August 2013 N O T I C

Explaining the R{sub K} and R{sub K{sup *}} anomalies

Energy Technology Data Exchange (ETDEWEB)

Ghosh, Diptimoy [Weizmann Institute of Science, Department of Particle Physics and Astrophysics, Rehovot (Israel)

2017-10-15

Recent LHCb results on R{sub K*}, the ratio of the branching fractions of B → K*μ{sup +}μ{sup -} to that of B → K*e{sup +}e{sup -}, for the dilepton invariant mass bins q{sup 2} ≡ m{sub ll}{sup 2} = [0.045-1.1] GeV{sup 2} and [1.1-6] GeV{sup 2} show approximately 2.5σ deviations from the corresponding Standard Model prediction in each of the bins. This, when combined with the measurement of R{sub K} (q{sup 2} = [1-6] GeV{sup 2}), a similar ratio for the decay to a pseudo-scalar meson, highly suggests lepton non-universal new physics in semi-leptonic B meson decays. In this work, we perform a model independent analysis of these potential new physics signals and identify the operators that do the best job in satisfying all these measurements. We show that heavy new physics, giving rise to q{sup 2} independent local 4-Fermi operators of scalar, pseudo-scalar, vector or axial-vector type, is unable to explain all the three measurements simultaneously, in particular R{sub K*} in the bin [0.045-1.1], within their experimental 1σ regions. We point out the possibility to explain R{sub K*} in the low bin by an additional light (

One-dimensional map lattices: Synchronization, bifurcations, and chaotic structures

DEFF Research Database (Denmark)

Belykh, Vladimir N.; Mosekilde, Erik

1996-01-01

The paper presents a qualitative analysis of coupled map lattices (CMLs) for the case of arbitrary nonlinearity of the local map and with space-shift as well as diffusion coupling. The effect of synchronization where, independently of the initial conditions, all elements of a CML acquire uniform...... dynamics is investigated and stable chaotic time behaviors, steady structures, and traveling waves are described. Finally, the bifurcations occurring under the transition from spatiotemporal chaos to chaotic synchronization and the peculiarities of CMLs with specific symmetries are discussed....

ASSESSMENT OF THE POTENTIAL FOR HYDROGEN GENERATION DURING GROUTING OPERATIONS IN THE R AND P REACTOR VESSELS

Energy Technology Data Exchange (ETDEWEB)

Wiersma, B.

2010-05-24

operations in the R-reactor vessel is low for the Portland cement. Alternatively, if the grout fill rate is less than 0.5 inch/min and the grout is maintained at a temperature of 80 C, the risk is again low. Although these calculations are conservative, there are some measures that may be taken to further minimize the potential for hydrogen evolution. (1) Minimize the temperature of the grout as much as practical. Lower temperatures will mean lower hydrogen generation rates. For P-reactor, grout temperatures less than 100 C should provide an adequate safety margin for the pH 8 and pH 10.4 grout formulations. For R-reactor, grout temperatures less than 70 C or 80 C will provide an adequate safety margin for the Portland cement. The other grout formulations are also viable options for R-reactor. (2) Minimize the grout fill rate as much as practical. Lowering the fill rate takes advantage of passivation of the aluminum components and hence lower hydrogen generation rates. For P-reactor, fill rates that are less than 2 inches/min for the ceramicrete and the silica fume grouts will reduce the chance of significant hydrogen accumulation. For R-reactor, fill rates less than 1 inch/min will again minimize the risk of hydrogen accumulation. (3) Ventilate the building as much as practical (e.g., leave doors open) to further disperse hydrogen. The volumetric hydrogen generation rates in the P-reactor vessel, however, are low for the pH 8 and pH 10.4 grout, (i.e., less than 0.97 ft{sup 3}/min). If further walk-down inspections of the reactor vessels suggest an increase in the actual areal density of aluminum, the calculations should be re-visited.

42 CFR 412.62 - Federal rates for inpatient operating costs for fiscal year 1984.

Science.gov (United States)

2010-10-01

... determines national adjusted DRG prospective payment rates for operating costs, for each inpatient hospital... DRG prospective payment rates for inpatient operating costs for such discharges in each region, for... classifications. (1) For purposes of paragraph (e) of this section, the following definitions apply: (i) The term...

D0 Central Tracking Solenoid Energization, Controls, Interlocks and Quench Protection Operating Procedures

International Nuclear Information System (INIS)

Hance, R.

1998-01-01

This procedure is used when it is necessary to operate the solenoid energization, controls, interlocks and quench detection system. Note that a separate procedure exists for operating the solenoid 'cryogenic' systems. Only D0 Control Room Operators or the Project Electrical Engineer are qualified to execute these procedures or operate the solenoid system. This procedure assumes that the operator is familiar with using the Distributed Manufacturing Automation and Control Software (DMACS).

Energiewende 4.0 - Chancen, Erfolgsfaktoren, Herausforderungen, Barrieren für Stadtwerke und Verteilnetzbetreiber

Science.gov (United States)

Rieger, Volker; Weber, Sven

Energiewende und Digitalisierung transformieren die Energiewirtschaft in noch nicht da gewesenem Maße. Durch den Wandel des linearen, vertikalen Geschäftsmodells in ein horizontales und vernetztes entstehen neue Geschäftsmodelle, in die vermehrt neue Anbieter aus anderen Branchen und Start-ups eintreten. Auf Basis langjähriger Beratungserfahrung erläutern die Autoren die zukünftige Geschäftslogik der Energiewelt 4.0. Anhand von Beispielen aus anderen Branchen zeigen sie dabei wesentliche Handlungsfelder speziell für regionale Energieunternehmen auf. Um in der neuen Energiewelt relevant zu bleiben, müssen Energieversorger ihre Kunden in den Fokus rücken, sich für Partnerschaften öffnen, in die Leistungsfähigkeit ihrer Infrastruktur investieren und v. a. einen Kulturwandel hin zu mehr Agilität und Offenheit vollführen.

Problems on triangular norms and related operators

Czech Academy of Sciences Publication Activity Database

Klement, E.P.; Mesiar, Radko; Pap, E.

2004-01-01

Roč. 23, č. 145 (2004), s. 471-479 ISSN 0165-0114 R&D Projects: GA ČR GA402/04/1026 Institutional research plan: CEZ:AV0Z1075907 Keywords : triangular norm * triangular conorm * aggregation operator Subject RIV: BA - General Mathematics Impact factor: 0.734, year: 2004

Liquid viscosity of low-GWP refrigerant mixtures (R32 + R1234yf) and (R125 + R1234yf)

International Nuclear Information System (INIS)

Dang, Yagu; Kamiaka, Takumi; Dang, Chaobin; Hihara, Eiji

2015-01-01

Highlights: • We measured liquid viscosity of low GWP refrigerant R1234yf binary mixtures. • Viscosity of R1234yf mixtures were correlated with the roughness hard-sphere method. • Viscosity of R1234yf mixtures were correlated with the Grunberg and Nissan method. - Abstract: In this work, the viscosity of R1234yf, (R32 + R1234yf), and (R125 + R1234yf) in one-phase liquid was measured. The combined expanded uncertainty of viscosity measurement apparatus of confidence of 0.95 (k = 2) is about 2.0%. The measurements of mixtures containing (30.0, 50.0, and 70.0) wt% R32 or R125 were carried out between T = (283.0 and 323.0) K (at intervals of T = 5 K) and P = (1.58 and 2.74) MPa, with a moving piston viscometer (VISCOpro 1600, accuracy ±1.0%) and a Coriolis flowmeter (Ultramass MKII, accuracy ±0.001 g/ml). The measured data were correlated with a hard-sphere (RSH) method and the Grunberg and Nissan method. The average absolute deviations are (2.2 and 3.3)% for the (R32 + R1234yf) and (R125 + R1234yf) mixtures by RSH method, (2.8 and 1.3)% for the (R32 + R1234yf) and (R125 + R1234yf) mixtures by Grunberg and Nissan method, while (3.5 and 2.4)% for the (R32 + R1234yf) and (R125 + R1234yf) mixtures by RefProp V9.1, respectively

Optical emission and mass spectroscopy of plasma processes in reactive DC pulsed magnetron sputtering of aluminium oxide

Czech Academy of Sciences Publication Activity Database

Novotný, Michal; Bulíř, Jiří; Pokorný, Petr; Bočan, Jiří; Fitl, Přemysl; Lančok, Ján; Musil, Jindřich

2010-01-01

Roč. 12, č. 3 (2010), 697-700 ISSN 1454-4164 R&D Projects: GA AV ČR IAA100100718; GA AV ČR KAN400100653; GA ČR GP202/09/P324 Institutional research plan: CEZ:AV0Z10100522 Keywords : reactive magnetron sputtering * alumina * plasma spectroscopy * mass spectroscopy * optical emission spectroscopy Subject RIV: BH - Optics, Masers, Lasers Impact factor: 0.412, year: 2010

Weighted estimates for the averaging integral operator

Czech Academy of Sciences Publication Activity Database

Opic, Bohumír; Rákosník, Jiří

2010-01-01

Roč. 61, č. 3 (2010), s. 253-262 ISSN 0010-0757 R&D Projects: GA ČR GA201/05/2033; GA ČR GA201/08/0383 Institutional research plan: CEZ:AV0Z10190503 Keywords : averaging integral operator * weighted Lebesgue spaces * weights Subject RIV: BA - General Mathematics Impact factor: 0.474, year: 2010 http://link.springer.com/article/10.1007%2FBF03191231

Weighted inequalities for Hardy-type operators involving suprema

Czech Academy of Sciences Publication Activity Database

Gogatishvili, Amiran; Opic, Bohumír; Pick, L.

2006-01-01

Roč. 57, č. 3 (2006), s. 227-255 ISSN 0010-0757 R&D Projects: GA ČR(CZ) GA201/01/0333; GA ČR(CZ) GA201/03/0935 Institutional research plan: CEZ:AV0Z10190503; CEZ:AV0Z10100521 Keywords : Hardy operators involving suprema * weighted inequalities Subject RIV: BA - General Mathematics

Energy and environmental performance assessment of R744 booster supermarket refrigeration systems operating in warm climates

DEFF Research Database (Denmark)

Gullo, Paride; Elmegaard, Brian; Cortella, Giovanni

2016-01-01

This paper presents a theoretical comparison among different commercial refrigeration systems in terms of annual energy consumption and environmental impact. Eight configurations were studied: a R744/R134a cascade refrigeration system (baseline), a conventional and an improved R744 booster system...... as on the running modes of a conventional European supermarket. A transition zone, which occurred between sub critical and transcritical operations, was adopted.The results showed that all the enhanced configurations may achieve a comparable energy saving to the one of the baseline in both the selected locations...

Crystal structure of (1S,3R,8R,9R-2,2-dichloro-3,7,7-trimethyl-10-methylenetricyclo[6.4.0.01,3]dodecan-9-ol

Directory of Open Access Journals (Sweden)

Ahmed Benzalim

2016-08-01

Full Text Available The title compound, C16H24Cl2O, was synthesized by treating (1S,3R,8S,9R,10S-2,2-dichloro-3,7,7,10-tetramethyl-9,10-epoxytricyclo[6.4.0.01,3]dodecane with a concentrated solution of hydrobromic acid. It is built up from three fused rings: a cycloheptane ring, a cyclohexyl ring bearing alkene and hydroxy substituents, and a cyclopropane ring bearing two chlorine atoms. The asymmetric unit contains two molecules linked by an O—H...O hydrogen bond. In the crystal, further O—H...O hydrogen bonds build up an R44(8 cyclic tetramer. One of the molecules presents disorder that affects the seven-membered ring. In both molecules, the six-membered rings display a chair conformation, whereas the seven-membered rings display conformations intermediate between boat and twist-boat for the non-disordered molecule and either a chair or boat and twist-boat for the disordered molecule owing to the disorder. The absolute configuration for both molecules is 1S,3R,8R,9R and was deduced from the chemical pathway and further confirmed by the X-ray structural analysis.

Tensor product of left n-invertible operators

Czech Academy of Sciences Publication Activity Database

Duggal, B.P.; Müller, Vladimír

2013-01-01

Roč. 215, č. 2 (2013), s. 113-125 ISSN 0039-3223 R&D Projects: GA ČR GA201/09/0473 Institutional support: RVO:67985840 Keywords : Banach space * essentially left n- invertible operator * left n-invertible operator Subject RIV: BA - General Mathematics Impact factor: 0.630, year: 2013 http://journals.impan.pl/cgi-bin/doi?sm215-2-2

42 CFR 136.412 - What questions must the IHS ask as part of the background investigation?

Science.gov (United States)

2010-10-01

..., exploitation, contact, or prostitution; crimes against persons; or offenses committed against children? If yes... Child Protection and Family Violence Prevention § 136.412 What questions must the IHS ask as part of the...: (1) Has the individual been arrested or charged with a crime involving a child? If yes, the...

Design and operating experience of the first commercial 0.4-5.0 MW fluidized bed boilers in Belarus

Energy Technology Data Exchange (ETDEWEB)

Borodulya, V.A.; Dobkin, S.M.; Telegin, E.M. [Academy of Sciences of Belarus, Minsk (Belarus). A.V. Luikov Heat and Mass Transfer Institute

1995-12-31

The present paper describes the development of AFBC systems for industrial and district heating in the range of capacities less than 5 MWth. The main goal is a plant which can be operated automatically and which meets the severe emission standards burning various kinds of coals including combustible wastes. First operating results of a 0.4 MWth plant are presented and demonstrate the basic feasibility of the concept. 6 refs., 1 fig., 4 tabs.

R.F. heating-influence of the magnetic field B0 on electron heating by ECRH

International Nuclear Information System (INIS)

Cunha Raposo, C. da; Aihara, S.; Sakanaka, P.H.

The results obtained in a series of experiments in the mirror machine 'LISA' are reported. A sequence of pulses of 2.45 GHz, 600 watts at a rate of 60 pulses/sec is applied to the plasma. The sequence is controlled by a self-reset system. Plasma parameters are studied as a function of the external magnetic field, B 0 , in two different configurations, large and small resonance space regions. For each region the mapping of magnetic field B 0 was made B sub(z) (r,z) axial and B sub(r) (r,z) radial distributions. These data were submitted to spatial and orbital distribution of the particles as well as flight and energy. Applying the microwave at the electron cyclotron frequency, electron temperature and density (T sub(e), n sub(e)), floating potential (V sub(f)), collision time, conductivity and confiment time are measured. The diagnostic is made with electrostatic probe, diamagnetic coil spectrograph, Hall probe and magnetometer. (L.C.) [pt

Magnetization processes in amorphous R-Co/R'-Co/R-Co sandwiches (R, R'=Y, Nd, Gd, Er)

International Nuclear Information System (INIS)

Dieny, B.; Givord, D.; Ndjaka, J.M.B.; Alameda, J.M.

1990-01-01

Sandwiches consisting of three amorphous layers (R 0.33 ,Co 0.67 )( 1000 A / R ' 0.33 ,Co 0.67 ) 1000 A / (R 0.33 Co 0.67 ) 1000 A , have been prepared by dc triode sputtering (R, R' are rare-earth elements). The systems chosen are such that the bulk magnetization alternates from one layer to the next or the coercivity of each layer is significantly different. Magnetic transitions are observed under field. They have been quantitatively analyzed in terms of successive reversals of magnetization in the different layers. The creation or annihilation of planar Bloch walls parallel to the surface are associated with the magnetic transitions. The wall energy and wall width depend essentially on the competition between exchange energy and Zeeman energy. It is suggested that the existence of such Bloch walls may favor magnetization reversal in thin films by coherent processes

The Dirac operator on a finite domain and the R-matrix method

International Nuclear Information System (INIS)

Grant, I P

2008-01-01

Relativistic effects in electron-atom collisions and photo-excitation and -ionization processes increase in importance as the atomic number of the target atom grows and spin-dependent effects increase. A relativistic treatment in which electron motion is described using the Dirac Hamiltonian is then desirable. A version of the popular nonrelativistic R-matrix package incorporating terms from the Breit-Pauli Hamiltonian has been used for modelling such processes for some years. The fully relativistic Dirac R-matrix method has been less popular, but is becoming increasingly relevant for applications to heavy ion targets, where the need to use relativistic wavefunctions is more obvious. The Dirac R-matrix method has been controversial ever since it was first proposed by Goertzel (1948 Phys. Rev. 73 1463-6), and it is therefore important to confirm that recent elaborate and costly applications of the method, such as, Badnell et al (2004 J. Phys. B: At. Mol. Phys. 37 4589) and Ballance and Griffin (2007 J. Phys. B: At. Mol. Opt. Phys. 40 247-58), rest on secure foundations. The first part of this paper analyses the structure of the two-point boundary-value problem for the Dirac operator on a finite domain, from which we construct a unified derivation of the Schroedinger (nonrelativistic) and Dirac (relativistic) R-matrix methods. Suggestions that the usual relativistic theory is not well founded are shown to be without foundation

Reducing the concentration to 0.4% enantiomeric excess hyperbaric levobupivacaine (s75: r25) provides unilateral spinal anesthesia. Study with different volumes.

Science.gov (United States)

Imbelloni, Luiz Eduardo; Gouveia, Marildo A; Carneiro, Antonio Fernando; Grigorio, Renata

2012-01-01

Unilateral spinal anesthesia may be obtained with hypobaric or hyperbaric solution. The objective of this study was to compare different doses of enantiomeric excess hyperbaric levobupivacaine to achieve unilateral spinal anesthesia. One hundred and twenty patients were randomized to receive 4 mg, 6 mg or 8 mg of 0.4% enantiomeric excess levobupivacaine. The solutions were administered at the L3-L4, with the patient in a lateral position and kept at this position according to dose administration for 5, 10 or 15 minutes. Sensory block (pinprick) and motor block (scale 0-3) were compared between the operated and contralateral sides. The onset of analgesia was rapid and comparable between groups. Sensory block was significantly higher in the operated than in nonoperated limb at all times of evaluation. Increasing the dose by 1 mL (2mg) corresponded to an increase of two segments in the mode for the operated side. In the operated side, motor block (MB = 3) of patients occurred in 31 (77.5%) with 4 mg, 38 (95%) with 6 mg, and 40 (100%) with 8 mg. There was a positive correlation between increased dose, blockade duration, and hypotension. All patients were satisfied with the technique used. Spinal anesthesia with different volumes of enantiomeric excess hyperbaric bupivacaine (S75: R25) provided a 78% incidence of unilateral spinal block, with the smallest dose used (4 mg) the most efficient. Copyright © 2012 Elsevier Editora Ltda. All rights reserved.

Overweight, asthma symptoms, atopy and pulmonary function in children of 4-12 years of age: findings from the SCAALA cohort in Salvador, Bahia, Brazil

OpenAIRE

Matos, SM; Jesus, SR; Saldiva, SR; Prado, MS; D'Innocenzo, S; Assis, AM; Rodrigues, LC; Alcantara-Neves, NM; Cruz, Á, A; Simões, SdeM; Barreto, ML; SCAALA (Social Change, Asthma and Allergy in Latin America) Stud,

2011-01-01

: To evaluate the association between overweight and the occurrence of asthma and atopy in a cohort of children of 4-12 years of age living in the city of Salvador in 2005. : Cross-sectional study nested in a cohort. : The metropolitan region of Salvador, Bahia, Brazil. : The study included 1129 children of 4-12 years age who presented complete information on the variables used here. Skin tests for allergy, spirometry, faecal parasitology, serum IgE and anthropometric surveys were conducted. ...

Bupivacaína levógira a 0,5% pura versus mistura enantiomérica de bupivacaína (S75-R25 a 0,5% em anestesia peridural para cirurgia de varizes Bupivacaína levógira a 0,5% pura versus mezcla enantiomerica bupivacaína (S75-R25 a 0,5% en anestesia peridural para cirugía de várices Plain 0.5% levogyrous bupivacaine versus 0.5% bupivacaine enantiomeric mixture (S75-R25 in epidural anesthesia for varicose vein surgery

Directory of Open Access Journals (Sweden)

José Delfino

2001-12-01

inferiores. La casuística, entretanto, no es aún suficiente para permitir conclusiones definitivas.BACKGROUND AND OBJECTIVES: The cardiotoxic effect of racemic bupivacaine (50:50 is still the major safety-related variable for regional blocks requiring higher concentrations and volumes. Recent animal studies suggested that the manipulation of racemic bupivacaine enantiomers could contribute for a better therapeutic efficacy by decreasing its potential toxicity. This study aimed at evaluating the efficacy of 0.5% bupivacaine enantiomeric mixture (S75-R25 as compared to plain S(-100% bupivacaine in lumbar epidural anesthesia for varicose vein surgery. METHODS: Participated in this randomized double-blind study 30 female patients aged 15 to 65 years, physical status ASA I or II scheduled for elective lower limb varicose vein surgery, who were allocated into two groups: S75-R25 Group - 20 ml (100 mg of 0.5% (S75-R25 bupivacaine; and Levogyrous Group - 20 ml (100 mg of 0.5% plain S(-100 bupivacaine without adjuvants. Characteristics of sensory and motor block as well as the incidence of side effects were investigated. RESULTS: Significant demographic differences and a longer surgical time were found in the S75-R25 Group. Faster spread and lower analgesic effects of the isomeric mixture were statistically significant. Motor block was significantly deeper in the S75-R25 Group. Side effects were negligible for both groups. CONCLUSIONS: Fewer side effects, good patients acceptance and the lack of post-operative transient neurological symptoms point towards the safety of both solutions in lumbar epidural anesthesia for elective varicose vein surgery. The sample, however, is still small for final conclusions.

Cyclosporine A-loaded and stem cell-seeded electrospun nanofibers for cell-based therapy and local immunosuppression

Czech Academy of Sciences Publication Activity Database

Holáň, Vladimír; Chudíčková, Milada; Trošan, Peter; Svobodová, Eliška; Krulová, Magdalena; Kubinová, Šárka; Syková, Eva; Širc, Jakub; Michálek, Jiří; Juklíčková, M.; Munzarová, M.; Zajícová, Alena

2011-01-01

Roč. 156, č. 3 (2011), s. 406-412 ISSN 0168-3659 R&D Projects: GA AV ČR KAN200520804; GA ČR GAP304/11/0653; GA ČR(CZ) GAP301/11/1568; GA ČR GD310/08/H077; GA MŠk 1M0506 Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z40500505; CEZ:AV0Z50520514 Keywords : nanofibers * immunosuppression * cell transfer Subject RIV: EC - Immunology Impact factor: 5.732, year: 2011

The IPR-R1 TRIGA Mark I Reactor in 39 years: Operations and general improvements

International Nuclear Information System (INIS)

Maretti Junior, Fausto; Prado Fernandes, Marcio; Oliveira, Paulo Fernando; Alves de Amorim, Valter

1999-01-01

The nuclear IPR-R1 TRIGA Mark I Reactor operating in the Nuclear Technology Development Center, originally Institute for Radioactive Research in Minas Gerais, Brazil, was dedicated in November 11, 1960. Initially operating for the production of radioisotopes for different uses, it started later to be used in large scale for neutron activation analysis and training of operators for nuclear power plants. Many improvements have been made throughout these years to provide a better performance in its operation and safety conditions. A new cooling system to operate until 300 kW, a new control rod mechanism, an aluminum tank for the reactor pool, an optimization in the pneumatic system, a new reactor control console and a general remodeling of the reactor laboratory were some of the improvements added. To prevent and mitigate the ageing effects, the reactor operation personnel is starting a program to minimize future operation problems. This paper describes the improvements made, the results obtained during the past 39 years, and the precautions taken to ensure future safe operation of the reactor to give operators better conditions of safe work. (author)

Using Web 2.0 (and Beyond?) in Space Flight Operations Control Centers

Science.gov (United States)

Scott, David W.

2010-01-01

Word processing was one of the earliest uses for small workstations, but we quickly learned that desktop computers were far more than e-typewriters. Similarly, "Web 2.0" capabilities, particularly advanced search engines, chats, wikis, blogs, social networking, and the like, offer tools that could significantly improve our efficiency at managing the avalanche of information and decisions needed to operate space vehicles in realtime. However, could does not necessarily equal should. We must wield two-edged swords carefully to avoid stabbing ourselves. This paper examines some Web 2.0 tools, with an emphasis on social media, and suggests which ones might be useful or harmful in real-time space operations co rnotl environments, based on the author s experience as a Payload Crew Communicator (PAYCOM) at Marshall Space Flight Center s (MSFC) Payload Operations Integration Center (POIC) for the International Space Station (ISS) and on discussions with other space flight operations control organizations and centers. There is also some discussion of an offering or two that may come from beyond the current cyber-horizon.

Astrocytes in Alzheimer's Disease

Czech Academy of Sciences Publication Activity Database

Verkhratsky, Alexei; Olabarria, M.; Noristani, H. N.; Yeh, C. Y.; Rodríguez Arellano, Jose Julio

2010-01-01

Roč. 7, č. 4 (2010), s. 399-412 ISSN 1933-7213 R&D Projects: GA ČR GA309/09/1696; GA ČR GA305/08/1384 Institutional research plan: CEZ:AV0Z50390703 Keywords : Astrocytes * neuroglia * neurodegeneration Subject RIV: FH - Neurology Impact factor: 6.084, year: 2010

Bound on largest r ∼< 0.1 from sub-Planckian excursions of inflaton

International Nuclear Information System (INIS)

Chatterjee, Arindam; Mazumdar, Anupam

2015-01-01

In this paper we will discuss the range of large tensor to scalar ratio, r, obtainable from a sub-Planckian excursion of a single, slow roll driven inflaton field. In order to obtain a large r for such a scenario one has to depart from a monotonic evolution of the slow roll parameters in such a way that one still satisfies all the current constraints of \\texttt(Planck), such as the scalar amplitude, the tilt in the scalar power spectrum, running and running of the tilt close to the pivot scale. Since the slow roll parameters evolve non-monotonically, we will also consider the evolution of the power spectrum on the smallest scales, i.e. at P s (k ∼ 10 16  Mpc −1 )∼< 10 −2 , to make sure that the amplitude does not become too large. All these constraints tend to keep the tensor to scalar ratio, r ∼< 0.1. We scan three different kinds of potential for supersymmetric flat directions and obtain the benchmark points which satisfy all the constraints. We also show that it is possible to go beyond r ∼> 0.1 provided we relax the upper bound on the power spectrum on the smallest scales

Renormalizing the Kinetic Energy Operator in Elementary Quantum Mechanics

Science.gov (United States)

Coutinho, F. A. B.; Amaku, M.

2009-01-01

In this paper, we consider solutions to the three-dimensional Schrodinger equation of the form [psi](r) = u(r)/r, where u(0) [is not equal to] 0. The expectation value of the kinetic energy operator for such wavefunctions diverges. We show that it is possible to introduce a potential energy with an expectation value that also diverges, exactly…

Electrochemical reaction mechanisms under various charge-discharge operating conditions for Li1.2Ni0.13Mn0.54Co0.13O2 in a lithium-ion battery

Science.gov (United States)

Konishi, Hiroaki; Hirano, Tatsumi; Takamatsu, Daiko; Gunji, Akira; Feng, Xiaoliang; Furutsuki, Sho; Okumura, Takefumi; Terada, Shohei; Tamura, Kazuhisa

2018-06-01

The potential in each state of charge (SOC) during charging of Li1.2Ni0.13Mn0.54Co0.13O2 is higher than that during discharging. In other words, the potential hysteresis occurs between charging and discharging. Furthermore, the potential in each SOC changes according to the charge-discharge operating conditions, indicating that the charge-discharge reaction mechanism is also affected. To clarify the effect of charge-discharge operating conditions on the electrochemical reaction, Li1.2Ni0.13Mn0.54Co0.13O2 was charged and discharged under various charge-discharge operating ranges, and open-circuit potential (OCP), crystal structure, and oxidation states of the transition metals were evaluated by electrochemical measurement, X-ray diffraction (XRD), and X-ray absorption fine structure (XAFS). These results indicate that OCP, lattice parameters, and oxidation states of the transition metals of Li1.2Ni0.13Mn0.54Co0.13O2 in each SOC are not constant. The XRD results indicate that two phases, namely, LiNi0.33Mn0.33Co0.33O2-like and Li2MnO3-like, exist in Li1.2Ni0.13Mn0.54Co0.13O2. For the LiNi0.33Mn0.33Co0.33O2-like phase, the relationship between OCP, lattice parameters, and oxidation states of the transition metals in each SOC is not affected by the charge-discharge operating conditions, indicating that extraction and insertion of lithium ions for the LiNi0.33Mn0.33Co0.33O2-like phase progresses at almost the same potential. Although the extraction and insertion of lithium ions for the Li2MnO3-like phase progresses at almost the same potential in the low-SOC region, the OCP and lattice parameter in each SOC in the high-SOC region are not constant. Therefore, the extraction of lithium ions from the Li2MnO3-like phase in the high-SOC region causes the potential hysteresis of Li1.2Ni0.13Mn0.54Co0.13O2.

MethylMix 2.0: an R package for identifying DNA methylation genes.

Science.gov (United States)

Cedoz, Pierre-Louis; Prunello, Marcos; Brennan, Kevin; Gevaert, Olivier

2018-04-14

DNA methylation is an important mechanism regulating gene transcription, and its role in carcinogenesis has been extensively studied. Hyper and hypomethylation of genes is a major mechanism of gene expression deregulation in a wide range of diseases. At the same time, high-throughput DNA methylation assays have been developed generating vast amounts of genome wide DNA methylation measurements. We developed MethylMix, an algorithm implemented in R to identify disease specific hyper and hypomethylated genes. Here we present a new version of MethylMix that automates the construction of DNA-methylation and gene expression datasets from The Cancer Genome Atlas (TCGA). More precisely, MethylMix 2.0 incorporates two major updates: the automated downloading of DNA methylation and gene expression datasets from TCGA and the automated preprocessing of such datasets: value imputation, batch correction and CpG sites clustering within each gene. The resulting datasets can subsequently be analyzed with MethylMix to identify transcriptionally predictive methylation states. We show that the Differential Methylation Values created by MethylMix can be used for cancer subtyping. olivier.gevaert@stanford.edu. https://bioconductor.org/packages/release/bioc/manuals/MethylMix/man/MethylMix.pdf. MethylMix 2.0 was implemented as an R package and is available in bioconductor.

Thermal Properties of Supercritical Carbon Dioxide by Monte Carlo Simulations

Czech Academy of Sciences Publication Activity Database

Colina, C. M.; Olivera-Fuentes, C. G.; Siperstein, F. R.; Lísal, Martin; Gubbins, K. E.

2003-01-01

Roč. 29, 6-7 (2003), s. 405-412 ISSN 0892-7022 R&D Projects: GA ČR GA203/02/0805 Grant - others:NSF(US) CHE-9876674291 Institutional research plan: CEZ:AV0Z4072921 Keywords : fluctuations * carbon dioxide * 2CLJQ Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.721, year: 2003

New population and phylogenetic features of the internal variation within mitochondrial DNA macro-haplogroup R0.

Directory of Open Access Journals (Sweden)

Vanesa Alvarez-Iglesias

Full Text Available BACKGROUND: R0 embraces the most common mitochondrial DNA (mtDNA lineage in West Eurasia, namely, haplogroup H (approximately 40%. R0 sub-lineages are badly defined in the control region and therefore, the analysis of diagnostic coding region polymorphisms is needed in order to gain resolution in population and medical studies. METHODOLOGY/PRINCIPAL FINDINGS: We sequenced the first hypervariable segment (HVS-I of 518 individuals from different North Iberian regions. The mtDNAs belonging to R0 (approximately 57% were further genotyped for a set of 71 coding region SNPs characterizing major and minor branches of R0. We found that the North Iberian Peninsula shows moderate levels of population stratification; for instance, haplogroup V reaches the highest frequency in Cantabria (north-central Iberia, but lower in Galicia (northwest Iberia and Catalonia (northeast Iberia. When compared to other European and Middle East populations, haplogroups H1, H3 and H5a show frequency peaks in the Franco-Cantabrian region, declining from West towards the East and South Europe. In addition, we have characterized, by way of complete genome sequencing, a new autochthonous clade of haplogroup H in the Basque country, named H2a5. Its coalescence age, 15.6+/-8 thousand years ago (kya, dates to the period immediately after the Last Glacial Maximum (LGM. CONCLUSIONS/SIGNIFICANCE: In contrast to other H lineages that experienced re-expansion outside the Franco-Cantabrian refuge after the LGM (e.g. H1 and H3, H2a5 most likely remained confined to this area till present days.

The architecture and operation of the CMS Tier-0

International Nuclear Information System (INIS)

Hufnagel, Dirk

2011-01-01

The Tier-0 processing system is the initial stage of the multi-tiered computing system of CMS. It takes care of the first processing steps of data at the LHC at CERN. The automated workflows running in the Tier-0 contain both low-latency processing chains for time-critical applications and bulk chains to archive the recorded data offsite the host laboratory. It is a mix between an online and offline system, because the data the CMS DAQ writes out initially is of a temporary nature. Most of the complexity in the design of this system comes from this unique combination of online and offline use cases and dependencies. In this talk, we want to present the software design of the CMS Tier-0 system and present an analysis of the 24/7 operation of the system in the 2009/2010 data taking periods.

Measurement of the ratio of branching fractions {ital B}({ital D}{sup 0}{r_arrow}{pi}{sup {minus}}{ital e}{sup +}{nu}{sub {ital e}})/{ital B}({ital D}{sup 0}{r_arrow}{ital K}{sup {minus}}{ital e}{sup +}{nu}{sub {ital e}})

Energy Technology Data Exchange (ETDEWEB)

Butler, F.; Fu, X.; Nemati, B.; Ross, W.R.; Skubic, P.; Wood, M.; Bishai, M.; Fast, J.; Gerndt, E.; Hinson, J.W.; McIlwain, R.L.; Miao, T.; Miller, D.H.; Modesitt, M.; Payne, D.; Shibata, E.I.; Shipsey, I.P.J.; Wang, P.N.; Gibbons, L.; Kwon, Y.; Roberts, S.; Thorndike, E.H.; Coan, T.E.; Dominick, J.; Fadeyev, V.; Korolkov, I.; Lambrecht, M.; Sanghera, S.; Shelkov, V.; Skwarnicki, T.; Stroynowski, R.; Volobouev, I.; Wei, G.; Artuso, M.; Gao, M.; Goldberg, M.; He, D.; Horwitz, N.; Moneti, G.C.; Mountain, R.; Muheim, F.; Mukhin, Y.; Playfer, S.; Rozen, Y.; Stone, S.; Xing, X.; Zhu, G.; Bartelt, J.; Csorna, S.E.; Egyed, Z.; Jain, V.; Gibaut, D.; Kinoshita, K.; Pomianowski, P.; Barish, B.; Chadha, M.; Chan, S.; Cowen, D.F.; Eigen, G.; Miller, J.S.; O`Grady, C.; Urheim, J.; Weinstein, A.J.; Wuerthwein, F.; Asner, D.M.; Athanas, M.; Bliss, D.W.; Brower, W.S.; Masek, G.; Paar, H.P.; Gronberg, J.; Korte, C.M.; Kutschke, R.; Menary, S.; Morrison, R.J.; Nakanishi, S.; Nelson, H.N.; Nelson, T.K.; Qiao, C.; Richman, J.D.; Roberts, D.; Ryd, A.; Tajima, H.; Witherell, M.S.; Balest, R.; Cho, K.; Ford, W.T.; Lohner, M.; Park, H.; Rankin, P.; Smith, J.G.; Alexander, J.P.; Bebek, C.; Berger, B.E.; Berkelman, K.; Bloom, K.; Browder, T.E.; Cassel, D.G.; Cho, H.A.; Coffman, D.M.; Crowcroft, D.S.; Dickson, M.; Drell, P.S.; Dumas, D.J.; Ehrlich, R.; Elia, R.; Gaidarev, P.; Garcia-Sciveres, M.; Gittelman, B.; Gray, S.W.; Hartill, D.L.; Heltsley, B.K.; Henderson, S.; Jones, C.D.; Jones, S.L.; Kandaswamy, J.; Katayama, N.; Kim, P.C.; Kreinick, D.L.; Liu, Y.; Ludwig, G.S.; Masui, J.; Mevissen, J.; Mistry, N.B.; Ng, C.R.; Nordberg, E.; Patterson, J.R.; Peterson, D.; Riley, D.; Soffer, A.; Avery, P.; Freyberger, A.; Lingel, K.; Rodriguez, J.; Yang, S.; Yelton, J.; Brandenburg, G.; Cinabro, D.; Liu, T.; Saulnier, M.; Wilson, R.; Yamamoto, H.; Bergfeld, T.; Eisenstein, B.I.; Ernst, J.; Gladding, G.E.; Gollin, G.D.; Palmer, M.; Selen, M.; Thaler, J.J.; Edwards, K.W.; McLean, K.W.; (CLEO Collabor...

1995-09-01

Using 3.0 fb{sup {minus}1} of data collected with the CLEO-II detector, we study the Cabibbo-suppressed decay {ital D}{sup 0}{r_arrow}{pi}{sup {minus}}{ital e}{sup +}{nu}{sub {ital e}}. The ratio of the branching fractions {ital B}({ital D}{sup 0}{r_arrow}{pi}{sup {minus}}{ital e}{sup +}{nu}{sub {ital e}})/{ital B}({ital D}{sup 0}{r_arrow}{ital K}{sup {minus}}{ital e}{sup +}{nu}{sub {ital e}}) is measured to be (10.3{plus_minus}3.9{plus_minus}1.3)%, corresponding to an upper limit of 15.6% at the 90% confidence level.

Představuje evropská politika předcházení klimatickým změnám pro průmysl regulační riziko?

Czech Academy of Sciences Publication Activity Database

Tošovská, Eva

2010-01-01

Roč. 4, č. 1 (2010), s. 4-12 ISSN 1802-212X R&D Projects: GA AV ČR IAA700850701 Institutional research plan: CEZ:AV0Z70850503 Keywords : climate changes * regulatory risk * European Union Emission Trading Scheme Subject RIV: AE - Management ; Administration

Lymphoscintigraphy and intra-operative gamma probe in detection of sentinel lymph node for breast cancer surgery

International Nuclear Information System (INIS)

Le Ngoc Ha; Le Manh Ha; Bui Quang Bieu

2011-01-01

Sentinel lymph node biopsy (SLNB) has been emerged as a highly accurate method of axillary staging in management of breast cancer patients. Sentinel lymph node detection (SLND) by lymphoscintigraphy and intra-operative gamma probe for SLNB have been widely used in the world. Objectives: the purpose of our study was to evaluate the result of techniques using lymphoscintigraphy and intra-operative gamma probe for SLND in breast carcinoma patients. Materials and Methods: 102 patients with early breast carcinoma were enrolled in the study. Lymphoscintigraphy using Tc-99m-human serum albumin colloid, intra-operative gamma probe were undergone for localization and SLNB. Total axillary lymph node was dissected in breast cancer surgery. Results: The success rate of lymphoscintigraphy and SLND was 98.0% (100/102 patients), mean number of sentinel lymph node (SLN)/patient was 1.56 ± 0.79 (ranged 1 - 3), number of lymphatic vessel/SLN was 1.5 ± 0.69 (ranged 1 - 4) and mean time for SLND on lymphoscintigraphy was 4.21 ± 13.4 minutes (2 - 15 minutes). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of radio-guided SLNB for axillary staging was 100%, 70.6%, 41.2%, 100% and 75.6 % respectively. Conclusions: radio-guided SLNB by lymphoscintigraphy and intra-operative gamma probe is feasible and reliable for axillary staging in early breast carcinoma patients. (author)

Renormings of C(K) spaces

Czech Academy of Sciences Publication Activity Database

Smith, Richard James; Troyanski, S.

2010-01-01

Roč. 104, č. 2 (2010), s. 375-412 ISSN 1578-7303 R&D Projects: GA ČR GA201/07/0394 Institutional research plan: CEZ:AV0Z10190503 Keywords : uniformly rotund norms * Frechet * Gateaux Subject RIV: BA - General Mathematics Impact factor: 0.400, year: 2010 http://www.springerlink.com/content/430027876375w58x/

Decommissioning of the Nuclear Reactors R2 and R2-0 at Studsvik, Sweden. General Data as called for under Article 37 of the Euratom Treaty

Energy Technology Data Exchange (ETDEWEB)

2009-01-15

This document describes the plans for decommissioning of the nuclear research and material test reactors R2 and R2-0, situated at the Studsvik site close to the city of Nykoeping, Sweden. The purpose of the document is to serve as information for the European Commission, and to fulfil the requirements of Article 37 of the Euratom Treaty. Studsvik is situated on the Baltic coast, about 20 km east of Nykoeping and 80 km southwest of Stockholm. The site comprises the reactors R2 and R2-0 and several facilities for material investigation and radioactive waste treatment and storage. The reactors were used for a number of different purposes from 1960 until June 2005, when they were shut down following a decision by the operator. Decommissioning of the reactor facility is planned to be completed in 2016 after dismantling and conditioning of radioactive parts and demolition of the facility. Solid and liquid radioactive wastes from the dismantling activities will be treated and stored on-site awaiting final disposal. The waste treatment facilities, which are situated in other buildings at the Studsvik site, are planned to continue operation during and after the decommissioning of the reactor facility. All nuclear fuel has been transferred to a separate storage facility and is being shipped to the US according to existing agreements. The objective of the planned dismantling activities is to achieve clearance of the facility to make it possible to either demolish the buildings or use them for other purposes. The operator has divided the planning for dismantling and demolition of the facility into three phases [1]: Dismantling 1, including primary system decontamination, dismantling of the reactors with systems in the reactor pool, draining, cleaning and temporary covering of the reactor pool. This phase has begun and is due to last till approximately December 2009. Dismantling 2, including dismantling of systems in the reactor facility, removal of equipment, radiological

Decommissioning of the Nuclear Reactors R2 and R2-0 at Studsvik, Sweden. General Data as called for under Article 37 of the Euratom Treaty

International Nuclear Information System (INIS)

2009-01-01

This document describes the plans for decommissioning of the nuclear research and material test reactors R2 and R2-0, situated at the Studsvik site close to the city of Nykoeping, Sweden. The purpose of the document is to serve as information for the European Commission, and to fulfil the requirements of Article 37 of the Euratom Treaty. Studsvik is situated on the Baltic coast, about 20 km east of Nykoeping and 80 km southwest of Stockholm. The site comprises the reactors R2 and R2-0 and several facilities for material investigation and radioactive waste treatment and storage. The reactors were used for a number of different purposes from 1960 until June 2005, when they were shut down following a decision by the operator. Decommissioning of the reactor facility is planned to be completed in 2016 after dismantling and conditioning of radioactive parts and demolition of the facility. Solid and liquid radioactive wastes from the dismantling activities will be treated and stored on-site awaiting final disposal. The waste treatment facilities, which are situated in other buildings at the Studsvik site, are planned to continue operation during and after the decommissioning of the reactor facility. All nuclear fuel has been transferred to a separate storage facility and is being shipped to the US according to existing agreements. The objective of the planned dismantling activities is to achieve clearance of the facility to make it possible to either demolish the buildings or use them for other purposes. The operator has divided the planning for dismantling and demolition of the facility into three phases [1]: Dismantling 1, including primary system decontamination, dismantling of the reactors with systems in the reactor pool, draining, cleaning and temporary covering of the reactor pool. This phase has begun and is due to last till approximately December 2009. Dismantling 2, including dismantling of systems in the reactor facility, removal of equipment, radiological

Circulating exosomal miR-27a and miR-130a act as novel diagnostic and prognostic biomarkers of colorectal cancer.

Science.gov (United States)

Wang, Shukui; Liu, Xiangxiang; Pan, Bei; Sun, Li; Chen, Xiaoxiang; Zeng, Kaixuan; Hu, Xiuxiu; Xu, Tao; Xu, Mu

2018-05-08

Colorectal cancer (CRC) is one of the most common cancers worldwide usually with poor prognosis due to the advanced stage when diagnosed. This study aimed to investigate whether specific circulating exosomal miRNAs could act as biomarkers for early diagnosis of CRC. A total of 369 peripheral blood samples were included in this study. In the discovery phase, circulating exosomal miR-27a and miR-130a were selected after synthetical analysis of two GEO datasets and TCGA database. The differential expression and diagnostic utility of miR-27a and miR-130a panel were validated using quantitative reverse-transcriptase PCR (qRT-PCR) and Receiver operating characteristic (ROC) curve analysis in subsequent training phase, validation phase and external validation phase. The prognosis of circulating exosomal miR-27a and miR-130a were investigated using the Kaplan-Meier method. The expression of exosomal miR-27a and miR-130a in plasma significantly increased in CRC. The area under ROC curves (AUCs) of miR-27a (miR-130a) were 0.773 (0.742) in the training phase, 0.82 (0.787) in the validation phase, and 0.746 (0.697) in the external validation phase. The combination of two miRNAs presented higher diagnostic utility for CRC (AUCs = 0.846, 0.898 and 0.801 for the training, validation, and external validation phases, respectively). CRC patients with high expression of circulating exosomal miR-27a or miR-130a underwent poorer prognosis. We identified a circulating exosomal miRNAs panel for the detection of CRC. The exosomal miR-27a and miR-130a panel in plasma may act as a non-invasive biomarker for early detection and predicting prognosis of CRC. Copyright ©2018, American Association for Cancer Research.

805 MHz Beta = 0.47 Elliptical Accelerating Structure R & D

Energy Technology Data Exchange (ETDEWEB)

S. Bricker; C. Compton; W. Hartung; M. Johnson; F. Marti; J. Popierlarski; R. C. York; et al

2008-09-22

A 6-cell 805 MHz superconducting cavity for acceleration in the velocity range of about 0.4 to 0.53 times the speed of light was designed. After single-cell prototyping, three 6-cell niobium cavities were fabricated. In vertical RF tests of the 6-cell cavities, the measured quality factors (Q{sub 0}) were between 7 {center_dot} 10{sup 9} and 1.4 {center_dot} 10{sup 10} at the design field (accelerating gradient of 8 to 10 MV/m). A rectangular cryomodule was designed to house 4 cavities per cryomodule. The 4-cavity cryomodule could be used for acceleration of ions in a linear accelerator, with focusing elements between the cryomodules. A prototype cryomodule was fabricated to test 2 cavities under realistic operating conditions. Two of the 6-cell cavities were equipped with helium tanks, tuners, and input coupler and installed into the cryomodule. The prototype cryomodule was used to verify alignment, electromagnetic performance, frequency tuning, cryogenic performance, low-level RF control, and control of microphonics.

New digital control system for the operation of the Colombian research reactor IAN-R1; Nuevo sistema de control digital para la operacion del reactor de investigacion Colombiano IAN-R1

Energy Technology Data Exchange (ETDEWEB)

Celis del A, L.; Rivero, T.; Bucio, F.; Ramirez, R.; Segovia, A.; Palacios, J., E-mail: lina.celis@inin.gob.mx [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

2015-09-15

En 2011, Mexico won the Colombian international tender for the renewal of instrumentation and control of the IAN-R1 Reactor, to Argentina and the United States. This paper presents the design criteria and the development made for the new digital control system installed in the Colombian nuclear reactor IAN-R1, which is based on a redundant and diverse architecture, which provides increased availability, reliability and safety in the reactor operation. This control system and associated instrumentation met all national export requirements, with the safety requirements established by the IAEA as well as the requirements demanded by the Colombian Regulatory Body in nuclear matter. On August 20, 2012, the Colombian IAN-R1 reactor reached its first criticality controlled with the new system developed at Instituto Nacional de Investigaciones Nucleares (ININ). On September 14, 2012, the new control system of the Colombian IAN-R1 reactor was officially handed over to the Colombian authorities, this being the first time that Mexico exported nuclear technology through the ININ. Currently the reactor is operating successfully with the new control system, and has an operating license for 5 years. (Author)

First Observation of the Cabibbo Suppressed Decay {ital B}{sup {ital +}}{ital {r_arrow} {bar {ital D}}}{sup {ital 0}}{ital K}{sup +}

Energy Technology Data Exchange (ETDEWEB)

Athanas, M.; Avery, P.; Jones, C.D.; Lohner, M.; Patton, S.; Prescott, C.; Yelton, J.; Zheng, J. [University of Florida, Gainesville, Florida 32611 (United States); Brandenburg, G.; Briere, R.A.; Ershov, A.; Gao, Y.S.; Kim, D.Y.; Wilson, R.; Yamamoto, H. [Harvard University, Cambridge, Massachusetts 02138 (United States); Browder, T.E.; Li, Y.; Rodriguez, J.L. [University of Hawaii at Manoa, Honolulu, Hawaii 96822 (United States); Bergfeld, T.; Eisenstein, B.I.; Ernst, J.; Gladding, G.E.; Gollin, G.D.; Hans, R.M.; Johnson, E.; Karliner, I.; Marsh, M.A.; Palmer, M.; Selen, M.; Thaler, J.J. [University of Illinois, Urbana-Champaign, Illinois 61801 (United States); Edwards, K.W. [Carleton University, Ottawa, Ontario, Canada K1S 5B6 and the Institute of Particle Physics (Canada); Bellerive, A.; Janicek, R.; MacFarlane, D.B.; Patel, P.M. [McGill University, Montreal, Quebec, Canada H3A 2T8 and the Institute of Particle Physics (Canada); Sadoff, A.J. [Ithaca College, Ithaca, New York 14850 (United States); Ammar, R.; Baringer, P.; Bean, A.; Besson, D.; Coppage, D.; Darling, C.; Davis, R.; Kotov, S.; Kravchenko, I.; Kwak, N.; Zhou, L. [University of Kansas, Lawrence, Kansas 66045 (United States); Anderson, S.; Kubota, Y.; Lee, S.J.; ONeill, J.J.; Poling, R.; Riehle, T.; Smith, A. [University of Minnesota, Minneapolis, Minnesota 55455 (United States); Alam, M.S.; Athar, S.B.; Ling, Z.; Mahmood, A.H.; Timm, S.; Wappler, F. [State University of New York at Albany, Albany, New York 12222 (United States); Anastassov, A.; Duboscq, J.E.; Fujino, D.; Gan, K.K.; Hart, T.; Honscheid, K.; Kagan, H.; Kass, R.; Lee, J.; Spencer, M.B.; Sung, M.; Undrus, A.; Wolf, A.; Zoeller, M.M. [The Ohio State University, Columbus, Ohio 43210 (United States); Nemati, B.; Richichi, S.J.; Ross, W.R.; Severini, H.; Skubic, P. [University of Oklahoma, Norman, Oklahoma 73019 (United States); Bishai, M.; Fast, J.; Hinson, J.W.; Menon, N.; Miller, D.H.; Shibata, E.I.; Shipsey, I.P.; and others

1998-06-01

We have observed the decay B{sup +}{r_arrow}{bar D}{sup 0} K{sup +} , using 3.3{times}10{sup 6} B{bar B} pairs collected with the CLEO II detector at the Cornell Electron Storage Ring. We find the ratio of branching fractions R{equivalent_to}B(B{sup +}{r_arrow}{bar D}{sup 0}K{sup +})/B(B{sup +}{r_arrow}{bar D}{sup 0}{pi}{sup +})=0.055{plus_minus}0.014{plus_minus}0.005 . {copyright} {ital 1998} {ital The American Physical Society}

78 FR 63867 - Change of Using Agency for Restricted Areas R-5115, NM, and R-6316, R-6317, and R-6318, TX

Science.gov (United States)

2013-10-25

... realignment of organizational responsibilities between federal agencies, U.S. Customs and Border Protection..., R-6317, and R-6318 in Texas. The transfer of using agency operational control occurs October 1, 2013...-6316, R- 6317, and R-6318 to reflect current organizational responsibilities. Environmental Review The...

Development, implementation and operational experience with 900 mm R1T pocket-type bearings at Oskarshamn unit 3 nuclear steam turbine generator

International Nuclear Information System (INIS)

Peel, P.; Roos, A.

2015-01-01

The Oskarshamn unit 3 nuclear steam turbine generator in Sweden is operated by OKG and, following the extensive PULS upgrade project, delivers an increased rated output of 1450 MW making it the most powerful BWR unit worldwide. Several turbine bearing incidents occurred in 2009 and 2010, which initiated a detailed root cause analysis to determine the reasons and propose appropriate mitigation measures to ensure reliable unit operation. Together with OKG, ALSTOM Power implemented a short-term solution to operate the unit over the winter period of 2010-11. Subsequently, during the annual outage in June 2011, a permanent solution involving a R1T pocket-type bearing design was installed at three shaft-line positions. Since the 1980's, R1T bearings with diameters from 250 to 670 mm have been operating in numerous full-speed (3000/3600 rpm) steam turbine generators. However, this was the first application of a R1T bearing developed at a diameter of 900 mm and for half-speed operation. This paper presents an overview of the bearing development and details the successful operational feedback gathered to date on the three installed bearings. In comparison with the three tilting pad bearing design, which has typically been used on large half-speed ALSTOM Power steam turbine generators to date, it confirms the R1T bearing design as a viable alternative. (authors)

Long Term Operation R and D to Investigate the Technical Basis for Life Extension and License Renewal Decisions

International Nuclear Information System (INIS)

Gaertner, John

2012-01-01

Establishing an improved technical basis for long term operation of existing plants is a nuclear industry priority. The Electric Power Research Institute (EPRI) has responded with a comprehensive Long Term Operation (LTO) Program addressing this need for existing nuclear power plants world-wide. The program supports both the business decisions necessary to achieve high performance operation and the licensing requirements for operation beyond 60 years. The program selects its R and D priorities in a structured and objective way with much industry input to provide useful results for decisions in the 2014 to 2019 time frame. The program is highly collaborative with U.S. Department of Energy (DOE) and with EPRI-member utilities. The R and D portfolio includes materials aging (metals, concrete, and cables), modernization of information and control technology, enhanced safety analysis, advanced fuel design, demonstration plant activities, life cycle management, and identification of aging management program need for subsequent license renewal. The program has focussed stakeholders world-wide on the technical issues of long term operation, and it is on-track to provide practical results for life extension and license renewal decisions. (author)

Electrochemical reactions of La(Ni,Cr)O.sub.3./sub. and La(Ni,Fe)O.sub.3./sub. in acidic aqueous solutions

Czech Academy of Sciences Publication Activity Database

Grygar, Tomáš

1999-01-01

Roč. 3, 7-8 (1999), s. 412-416 ISSN 1432-8488 R&D Projects: GA AV ČR IPP1067701 Institutional research plan: CEZ:AV0Z4032918 Keywords : Chromium oxides * Iron oxides * Redox reactions * Perovskite Subject RIV: CG - Electrochemistry Impact factor: 1.097, year: 1998

Charging of Self-Doped Poly(Anilineboronic Acid) Films Studied by in Situ ESR/UV/Vis/NIR Spectroelectrochemistry and ex Situ FTIR Spectroscopy

Czech Academy of Sciences Publication Activity Database

Moraes, I. R.; Kalbáč, Martin; Dmitrieva, E.; Dunsch, L.

2011-01-01

Roč. 12, č. 16 (2011), s. 2920-2924 ISSN 1439-4235 R&D Projects: GA ČR GC203/07/J067 Institutional research plan: CEZ:AV0Z40400503 Keywords : conducting polymers * films * FTIR spectroscopy Subject RIV: CG - Electrochemistry Impact factor: 3.412, year: 2011

Performance of classification confidence measures in dynamic classifier systems

Czech Academy of Sciences Publication Activity Database

Štefka, D.; Holeňa, Martin

2013-01-01

Roč. 23, č. 4 (2013), s. 299-319 ISSN 1210-0552 R&D Projects: GA ČR GA13-17187S Institutional support: RVO:67985807 Keywords : classifier combining * dynamic classifier systems * classification confidence Subject RIV: IN - Informatics, Computer Science Impact factor: 0.412, year: 2013

The gravitational wave detector NAUTILUS operating at T = 0.1 K

International Nuclear Information System (INIS)

Astone, P.; Bassan, M.; Bonifazi, P.

1997-02-01

They report on the ultralow-temperature resonant-mass gravitational-wave detector NAUTILUS operating at the Frascati INFN Laboratories. The present aim of this detector is to achieve a sensitivity sufficient to detect bursts of gravitational radiation from sources located in our Galaxy and in the local group. Progress in transducer technology is likely to lead to sensitivities that will enable them to observe events from sources as far away as the Virgo cluster of galaxies. They describe the cryogenic apparatus, readout system cosmic-ray veto system, and give first results obtained during one year of continuous operation at T = 0.1 K. In particular the Brownian noise of the detector at T = 0.1 K was measured. The measured strain sensitivity was h-tilde ∼ 6 10 -22 Hz -1/2 at the frequencies of the two modes, 908 Hz and 924 Hz, with bandwidths of about 1 Hz

Advantages of combined touch screen technology and text hyperlink for the pathology grossing manual: a simple approach to access instructive information in biohazardous environments.

Science.gov (United States)

Qu, Zhenhong; Ghorbani, Rhonda P; Li, Hongyan; Hunter, Robert L; Hannah, Christina D

2007-03-01

Gross examination, encompassing description, dissection, and sampling, is a complex task and an essential component of surgical pathology. Because of the complexity of the task, standardized protocols to guide the gross examination often become a bulky manual that is difficult to use. This problem is further compounded by the high specimen volume and biohazardous nature of the task. As a result, such a manual is often underused, leading to errors that are potentially harmful and time consuming to correct-a common chronic problem affecting many pathology laboratories. To combat this problem, we have developed a simple method that incorporates complex text and graphic information of a typical procedure manual and yet allows easy access to any intended instructive information in the manual. The method uses the Object-Linking-and-Embedding function of Microsoft Word (Microsoft, Redmond, WA) to establish hyperlinks among different contents, and then it uses the touch screen technology to facilitate navigation through the manual on a computer screen installed at the cutting bench with no need for a physical keyboard or a mouse. It takes less than 4 seconds to reach any intended information in the manual by 3 to 4 touches on the screen. A 3-year follow-up study shows that this method has increased use of the manual and has improved the quality of gross examination. The method is simple and can be easily tailored to different formats of instructive information, allowing flexible organization, easy access, and quick navigation. Increased compliance to instructive information reduces errors at the grossing bench and improves work efficiency.

R0-modeling as a tool for early warning and surveillance of exotic vector borne diseases in Denmark

DEFF Research Database (Denmark)

Bødker, Rene

2011-01-01

for predicting permanent establishment of presently exotic diseases, mean temperatures may not predict the true potential for local spread and limited outbreaks resulting from accidental introductions in years with temporary periods of warm weather. DTU-Veterinary Institute is developing a system for continuous...... a truly risk based surveillance system for insect borne diseases. R0 models for many vector borne diseases are simple and the available estimates of model parameters like vector densities and survival rates may be uncertain. The quantitative value of R0 estimated from such models is therefore likely......Modeling the potential transmission intensity of insect borne diseases with climate driven R0 process models is frequently used to assess the potential for veterinary and human infections to become established in non endemic areas. Models are often based on mean temperatures of an arbitrary time...

Environmental Health concerns in natural and man-made environments

Science.gov (United States)

Bergtholdt, C. P.

1975-01-01

Industrial hygene and environmental health aspects of ground operation at the Jet Propulsion Laboratory were investigated. Major areas of concern are: (1) toxic substances, (2) noise pollution, (3) electromagnetic radiation; and (4) biohazards and sanitation. Each of these categories are also studied in a closed environment, such as encountered aboard of a spacecraft.

Study of short-lived fission products with the aid of an isotope separator connected to reactor R2-0

International Nuclear Information System (INIS)

Rudstam, G.

1976-01-01

This report constitutes a final report on project 74-3289 together with a preliminary report for project 75-3332. These projects have been included in the budget years 1974/75 and 1975/76 as a contribution to the operating costs of reactor R2-0 at Studsvik. The reactor was used for experimental studies on short-lived fission products with OSIRIS isotope-separator equipment. The scientific programme is very broad. It comprises, in the first place, characterisation of fission products (a study of their excitation levels, measurement of decay properties such as half-life and emission of delayed neutrons, determination of neutron energy spectrum, determination of total decay energy, etc.). An important application of this field of research is the determination of decay heat in nuclear fuel. The programme thus comprises research of a fundamental character and applied research. (H.E.G.)

Operation of Beaver Valley Power Station, Unit 2, Docket No. 50-412, Beaver County, Pennsylvania

International Nuclear Information System (INIS)

1985-09-01

The final environmental impact statement (EPA No. 850438F) assesses the effects of operating a pressurized water reactor in Pennsylvania on the south bank of the Ohio River, which would serve as the final heat sink for the cooling system. Operation of Unit 2 would add 836 MW of capacity and increase system reliability. The plant would employ 465 at an $18 million payroll. Facilities for the plant would take up 56 acres of agricultural land. The operation result in both water and noise pollution. There is only a small probability of impacts due to potential radiation exposure. The Federal Water Pollution Control Act of 1972 and Nuclear Regulatory Commission Regulations require the impact statement

Concurrency can drive an HIV epidemic by moving R0 across the epidemic threshold

NARCIS (Netherlands)

Leung, Ka Yin; Kretzschmar, Mirjam

2015-01-01

OBJECTIVE: The objective of this study is to investigate whether concurrency can drive an HIV epidemic by moving R0 across the epidemic threshold. DESIGN AND METHODS: We use a mathematical framework for a dynamic partnership network and the spread of a one-stage infection to study how concurrency is

Form factors of the transitions {gamma}{sup *}{pi}{sup 0} {r_arrow} {gamma} and {gamma}{sup *}{eta}{r_arrow}{gamma}

Energy Technology Data Exchange (ETDEWEB)

Afanasev, A. [Continuous Electron Beam Accelerator Facility, Newport News, VA (United States)

1994-04-01

The author discusses possibilities to study {gamma}*{pi}{sup 0} and {gamma}*{eta} {r_arrow} {gamma} transition form factors at CEBAF energies. The author shows that for 4 GeV electron beam, these form factors can be measured at CEBAF for the 4-momentum transfers Q{sup 2} {le} 2.5 (GeV/c){sup 2} using virtual Compton scattering on the proton and nuclear target in the kinematic regime of low momentum transfers to the target. These measurements can be extended to Q{sup 2} {le} 4.0 (GeV/c){sup 2} using the electron beam with the energy 6 GeV.

Host specialisation of leaf chewing insects in a New Guinea rainforest

Czech Academy of Sciences Publication Activity Database

Novotný, Vojtěch; Basset, Y.; Miller, S. E.; Drozd, P.; Čížek, Lukáš

2002-01-01

Roč. 71, - (2002), s. 400-412 ISSN 0021-8790 R&D Projects: GA ČR GA206/99/1112; GA AV ČR IAA6007705; GA MŠk ME 041 Institutional research plan: CEZ:AV0Z5007907 Keywords : herbivore communities * species richness * tropical forests Subject RIV: EH - Ecology, Behaviour Impact factor: 2.905, year: 2002

Development of microsatellite markers specific for the short arm of rye (Secale cereale L.) chromosome 1

Czech Academy of Sciences Publication Activity Database

Kofler, R.; Bartoš, Jan; Gong, L.; Stift, G.; Suchánková, Pavla; Šimková, Hana; Berenyi, M.; Burg, K.; Doležel, Jaroslav; Lelley, T.

2008-01-01

Roč. 117, č. 6 (2008), s. 915-926 ISSN 0040-5752 R&D Projects: GA ČR GA521/04/0607; GA ČR GP521/06/P412 Institutional research plan: CEZ:AV0Z50380511 Keywords : NON-LTR RETROTRANSPOSONS * ORYZA-SATIVA L. * PLANT GENOMES Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.490, year: 2008

Smith-Lemli-Opitz syndrome: Moleculat-genetic analysis of ten families

Czech Academy of Sciences Publication Activity Database

Kozák, L.; Francová, H.; Hrabincová, E.; Procházková, D.; Jittnerová, V.; Bezděch, V.; Šimek, Petr

2000-01-01

Roč. 23, - (2000), s. 409-412 ISSN 0141-8955 R&D Projects: GA ČR GA302/97/0742; GA MZd IZ4376; GA MZd IZ4379 Institutional research plan: CEZ:AV0Z5007907 Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.307, year: 2000

Association of pre-operative medication use with post-operative delirium in surgical oncology patients receiving comprehensive geriatric assessment.

Science.gov (United States)

Jeong, Young Mi; Lee, Eunsook; Kim, Kwang-Il; Chung, Jee Eun; In Park, Hae; Lee, Byung Koo; Gwak, Hye Sun

2016-07-07

Older patients undergoing surgery tend to have a higher frequency of delirium. Delirium is strongly associated with poor surgical outcomes. This study evaluated the association between pre-operative medication use and post-operative delirium (POD) in surgical oncology patients receiving comprehensive geriatric assessment (CGA). A total of 475 patients who were scheduled for cancer surgery and received CGA from January 2014 to June 2015 were included. Pre-operative medication review through CGA was conducted on polypharmacy (≥5 medications), delirium-inducing medications (DIMs), fall-inducing medications (FIMs), and potentially inappropriate medications (PIMs). POD was confirmed by psychiatric consultation, and DSM-V criteria were used for diagnosing delirium. The model fit of the prediction model was assessed by computing the Hosmer-Lemeshow goodness-of-fit test. Effect size was measured using the Nagelkerke R(2). Discrimination of the model was assessed by an analysis of the area under receiver operating curve (AUROC). Two models were constructed for multivariate analysis based on univariate analysis; model I included dementia and DIM in addition to age and sex, and model II included PIM instead of DIM of model I. Every one year increase of age increased the risk of POD by about 1.1-fold. DIM was a significant factor for POD after adjusting for confounders (AOR 12.78, 95 % CI 2.83-57.74). PIM was also a significant factor for POD (AOR 5.53, 95 % CI 2.03-15.05). The Hosmer-Lemeshow test results revealed good fits for both models (χ(2) = 3.842, p = 0.871 for model I and χ(2) = 8.130, p = 0.421 for model II). The Nagelkerke R(2) effect size and AUROC for model I was 0.215 and 0.833, respectively. Model II had the Nagelkerke R(2)effect size of 0.174 and AUROC of 0.819. These results suggest that pharmacists' comprehensive review for pre-operative medication use is critical for the post-operative outcomes like delirium in older patients.

Limiting Normal Operator in Quasiconvex Analysis

Czech Academy of Sciences Publication Activity Database

Aussel, D.; Pištěk, Miroslav

2015-01-01

Roč. 23, č. 4 (2015), s. 669-685 ISSN 1877-0533 R&D Projects: GA ČR GA15-00735S Institutional support: RVO:67985556 Keywords : Quasiconvex function * Sublevel set * Normal operator Subject RIV: BA - General Mathematics Impact factor: 0.973, year: 2015 http://library.utia.cas.cz/separaty/2015/MTR/pistek-0453552.pdf

Targeting TMPRSS2 ERG in Prostate Cancer

Science.gov (United States)

2016-09-01

kinome library, using physiologic cell based assays of ERG activity. We made lentivirus expressing multiple shRNAs targeting each candidate 9...MDV3100 reverses the effect of R1881 (compare columns 2 and 3). Interestingly, PKCi inhibited a subset of androgen induced genes ( column 4...expenditures Nothing to report. Significant changes in use or care of human subjects, vertebrate animals, biohazards, and/or select agents Nothing to

An investigation into the RCCI engine operation under low load and its achievable operational range at different engine speeds

International Nuclear Information System (INIS)

Wang, Yifeng; Zhu, ZhongWen; Yao, Mingfa; Li, Tie; Zhang, Weijing; Zheng, Zunqing

2016-01-01

Highlights: • The response of allowable RCCI operating range to engine speed variation is studied. • The RCCI and diesel LTC engine operations at are compared at low engine load. • The potential of expanding RCCI operating range at low engine speed is explored. - Abstract: Reactivity controlled compression ignition (RCCI) is demonstrated as a promising combustion strategy to achieve high efficiency and clean combustion. However, less effort has been devoted to examine the achievable RCCI operational range over a wide range of engine speed. In addition, previous studies have found that superior EGR rate and high diesel/gasoline fuel ratio are required to ease the extension of the low-load operating range of RCCI regime. Even then, relatively high CO and HC (unburned hydrocarbon) emissions and the accompanying fuel con-sum ption penalty still remain a problem to be resolved. Therefore, in this work the potential of diesel-fueled LTC to achieve simultaneously low NOx and soot emissions while maintaining high thermal efficiency at low load (IMEP ≈0.23–0.26 MPa) is investigated and compared with the gasoline/diesel RCCI strategy. The results show that the diesel LTC operation can yield slightly higher soot and NOx emissions (soot: 0.002 g/kW h, NOx: 0.446 g/kW h), but CO and HC emissions as well as the fuel consumption are much lower than the RCCI strategy, implying the diesel LTC regime may be more suitable for low-load operations. In addition, the RCCI operational range at speeds ranging from 900 to 2500 r/min is determined, the results show that the maximum achievable load (IMEP) increases with an increase in speed, and a maximum IMEP of 1.2 MPa can be achieved at an engine speed of 2300 r/min. Ultra-low NOx and soot emissions (soot < 0.003 g/kW h, NOx < 0.4 g/kW h) can be achieved under the maximum loading conditions at each speed investigated. However, high levels of CO and HC emissions still remain a big problem to be solved. The lowest fuel consumption

The low-energy spectrum of (2, 0) theory on T5 x R

International Nuclear Information System (INIS)

Henningson, Maans

2008-01-01

We consider the ADE-series of (2, 0) supersymmetric quantum theories on T 5 x R, where the first factor is a flat spatial five-torus, and the second factor denotes time. The quantum states of such a theory Φ are characterized by a discrete quantum number f element of H 3 (T 5 , C), where the finite abelian group C is the center subgroup of the corresponding simply connected simply laced Lie group G. At energies that are low compared to the inverse size of the T 5 , the spectrum consists of a set of continua of states, each of which is characterized by the value of f and some number 5r of additional continuous parameters. By exploiting the interpretation of this theory as the ultraviolet completion of maximally supersymmetric Yang-Mills theory on T 4 x S 1 x R with gauge group G adj = G/C and coupling constant g given by the square root of the radius of the S 1 factor, one may compute the number N f r (Φ) of such continua. We perform these calculations in detail for the A- and D-series. While the Yang-Mills theory formalism is manifestly invariant under the SL 4 (Z) mapping class group of T 4 , the results are actually found to be invariant under the SL 5 (Z) mapping class group of T 5 , which provides a strong consistency check.

A 0.8V, 7μA, rail-to-rail input/output, constant Gm operational amplifier in standard digital 0.18μm CMOS

DEFF Research Database (Denmark)

Citakovic, J; Nielsen, I. Riis; Nielsen, Jannik Hammel

2005-01-01

A two-stage amplifier, operational at 0.8V and drawing 7μA, has been integrated in a standard digital 0.18μm CMOS process. Rail-to-rail operations at the input are enabled by complementary transistor pairs with gm control. The efficient rail-to-rail output stage is biased in class AB. The measured...

Antibound states for a class of one-dimensional Schroedinger Operators

International Nuclear Information System (INIS)

Angeletti, A.

1980-01-01

Let delta(x) be the Dirac's delta, q(x) element of L 1 (R) L 2 (R) be a real valued function, and lambda, μ element of R; we will consider the following class of one-dimensional formal Schroedinger operators on L 2 (R) H(lambda,μ) = - (d 2 /dx 2 ) + lambdadelta(x) + μq(x). It is known that to the formal operator H(lambda, μ) may be associated a selfadjoint operator H(lambda, μ) on L 2 (R). If q is of finite range, for lambda < 0 and /μ/ is small enough, we prove that H(lambda,μ) has an antibound state; that is the resolvent of H(lambda,μ) has a pole on the negative real axis on the second Riemann sheet. (orig.)

[Results of surgical treatment in ampullary and pancreatic carcinoma and its prognostic parameters after R0-resection].

Science.gov (United States)

Ridwelski, K; Meyer, F; Schmidt, U; Lippert, H

2005-08-01

Resection is currently the only established reasonable therapeutic option with curative potential in pancreatic and ampullary carcinoma. The aim of the study was i) to analyze value and results of surgical therapy and ii) to detect the prognostic parameters, which determine significantly higher survival rates. Two-hundred-twenty patients with pancreatic and ampullary carcinoma (mean age, 61.4 years; 104 females/116 males) underwent surgery. Histologic investigation revealed 19 carcinomas of the papilla of Vater and 201 ductal pancreatic carcinomas. In 126 patients, stage IV a or b tumors were found, in addition, stage I (n =26), II (n = 17) and III (n = 51). Survival-rate was determined according to the method by Kaplan/Meier. Survival was compared using log-rank test. Association of several or multiple parameters with survival was tested using Cox model. Hundred-ten patients underwent tumor resection with primary curative intention (50 %): 96 resections of the pancreatic head, 2 total pancreatectomies and 12 left resections of the pancreas. R0-resection was achieved in 94 patients (42.7 %), whereas intervention was classified R1 in 10 and R2 in 6 cases. In addition, 60 palliative interventions (28 gastroenterostomies, 17 biliodigestive anastomoses, 15 anastomoses at both sites) and 50 explorative laparotomies were performed. In 42.3 % of patients, postoperative complications were found, but only 12/220 individuals died (overall letality, 5.4 %). Postoperative letality of curative pancreatic resections was 3.6 % (palliative intervention, 6.7 %; explorative laparotomy, 8.8 %). Five-year survival-rate of carcinoma of the papilla of Vater and pancreatic carcinoma was 73.3 % and 16.2 %, respectively (median survival time was 66.0 and 14.0 months, respectively). Taken together all other interventions, median survival time ranged between 4.0 (palliative intervention) to 10.0 months (R1-resection). No patient survived 5 years. Therefore, the most relevant prognostic

Continuous country-wide rainfall observation using a large network of commercial microwave links: Challenges, solutions and applications

Science.gov (United States)

Chwala, Christian; Boose, Yvonne; Smiatek, Gerhard; Kunstmann, Harald

2017-04-01

Commercial microwave link (CML) networks have proven to be a valuable source for rainfall information over the last years. However, up to now, analysis of CML data was always limited to certain snapshots of data for historic periods due to limited data access. With the real-time availability of CML data in Germany (Chwala et al. 2016) this situation has improved significantly. We are continuously acquiring and processing data from 3000 CMLs in Germany in near real-time with one minute temporal resolution. Currently the data acquisition system is extended to 10000 CMLs so that the whole of Germany is covered and a continuous country-wide rainfall product can be provided. In this contribution we will elaborate on the challenges and solutions regarding data acquisition, data management and robust processing. We will present the details of our data acquisition system that we run operationally at the network of the CML operator Ericsson Germany to solve the problem of limited data availability. Furthermore we will explain the implementation of our data base, its web-frontend for easy data access and present our data processing algorithms. Finally we will showcase an application of our data in hydrological modeling and its potential usage to improve radar QPE. Bibliography: Chwala, C., Keis, F., and Kunstmann, H.: Real-time data acquisition of commercial microwave link networks for hydrometeorological applications, Atmos. Meas. Tech., 9, 991-999, doi:10.5194/amt-9-991-2016, 2016

Assessing and Adapting Scientific Results for Space Weather Research to Operations (R2O)

Science.gov (United States)

Thompson, B. J.; Friedl, L.; Halford, A. J.; Mays, M. L.; Pulkkinen, A. A.; Singer, H. J.; Stehr, J. W.

2017-12-01

Why doesn't a solid scientific paper necessarily result in a tangible improvement in space weather capability? A well-known challenge in space weather forecasting is investing effort to turn the results of basic scientific research into operational knowledge. This process is commonly known as "Research to Operations," abbreviated R2O. There are several aspects of this process: 1) How relevant is the scientific result to a particular space weather process? 2) If fully utilized, how much will that result improve the reliability of the forecast for the associated process? 3) How much effort will this transition require? Is it already in a relatively usable form, or will it require a great deal of adaptation? 4) How much burden will be placed on forecasters? Is it "plug-and-play" or will it require effort to operate? 5) How can robust space weather forecasting identify challenges for new research? This presentation will cover several approaches that have potential utility in assessing scientific results for use in space weather research. The demonstration of utility is the first step, relating to the establishment of metrics to ensure that there will be a clear benefit to the end user. The presentation will then move to means of determining cost vs. benefit, (where cost involves the full effort required to transition the science to forecasting, and benefit concerns the improvement of forecast reliability), and conclude with a discussion of the role of end users and forecasters in driving further innovation via "O2R."

System performance with R407A, R407B, R407C compared to R22

DEFF Research Database (Denmark)

Knudsen, Hans Jørgen Høgaard

1997-01-01

both the cooling capacity and COP are smaller then the cooling capacity and COP with R22. The cooling capacity for R407A and R407B is lower than the capacity for R22 for brine temperatures less than 0 C and higher then the cooling capacity for R22 for brine temperatures higher than 0 C. The COP for R......407A and R407B er lower than the COP for R22.The volumetric and isentropic efficiency of the compressor are with mixture higher than the volumetric and isentropic efficiency with R22.......The article presents the results obtained by substituting R22 with mixture of R32/R125/R134A (R407A, R407B and R407C) in an existing refrigeration plant. Cooling capacity, coefficient of performance and heat transfer coefficient in the evaporator have been measured.The results show that for R407C...

19 CFR 351.412 - Levels of trade; adjustment for difference in level of trade; constructed export price offset.

Science.gov (United States)

2010-04-01

... Price, Constructed Export Price, Fair Value, and Normal Value § 351.412 Levels of trade; adjustment for.... The Secretary is authorized to adjust normal value to account for such a difference. (See section 773... value for a difference in level of trade if: (1) The Secretary calculates normal value at a different...

An open and extensible framework for spatially explicit land use change modelling in R: the lulccR package (0.1.0)

Science.gov (United States)

Moulds, S.; Buytaert, W.; Mijic, A.

2015-04-01

Land use change has important consequences for biodiversity and the sustainability of ecosystem services, as well as for global environmental change. Spatially explicit land use change models improve our understanding of the processes driving change and make predictions about the quantity and location of future and past change. Here we present the lulccR package, an object-oriented framework for land use change modelling written in the R programming language. The contribution of the work is to resolve the following limitations associated with the current land use change modelling paradigm: (1) the source code for model implementations is frequently unavailable, severely compromising the reproducibility of scientific results and making it impossible for members of the community to improve or adapt models for their own purposes; (2) ensemble experiments to capture model structural uncertainty are difficult because of fundamental differences between implementations of different models; (3) different aspects of the modelling procedure must be performed in different environments because existing applications usually only perform the spatial allocation of change. The package includes a stochastic ordered allocation procedure as well as an implementation of the widely used CLUE-S algorithm. We demonstrate its functionality by simulating land use change at the Plum Island Ecosystems site, using a dataset included with the package. It is envisaged that lulccR will enable future model development and comparison within an open environment.

THREE-STAGE COMBUSTION (REBURNING) ON A FULL SCALE OPERATING BOILER IN THE U.S.S.R.

Science.gov (United States)

The report gives results of a program to complete preliminary design of a three- stage combustion (reburn) system for nitrogen oxide (NOx) emissions control on an operating boiler in the U. S.S. R. he program to design the reburn system consisted of five tasks: visiting the Ladyz...

Real time monitoring system of the operation variables of the TRIGA IPR-R1 nuclear research reactor

International Nuclear Information System (INIS)

Ricardo, Carla Pereira; Mesquita, Amir Zacarias

2007-01-01

During the last two years all the operation parameters of the TRIGA IPR-R1 were monitored and real time indicated bu the data acquisition system developed for the reactor. All the information were stored on a rigid disk, at the collection system computer, leaving the information on the reactor performance and behaviour available for consultation in a chronological order. The data acquisition program has been updated and new reactor operation parameters were included for increasing the investigation and experiments possibilities. The register of reactor operation variables are important for the immediate or subsequent safety analyses for reporting the reactor operations to the external organizations. This data acquisition satisfy the IAEA recommendations. (author)

Fixed Point Theorems for T-Ciric Quasi-contractive Operator in CAT(0 Spaces

Directory of Open Access Journals (Sweden)

G. S. Saluja

2013-08-01

Full Text Available The purpose of this paper to study a three-step iterative algorithm for T-Ciric quasi-contractive (TCQC operator in the framework of CAT(0 spaces and establish strong convergence theorems for above said scheme and operator. Our results improve and extend the recent corresponding results from the existing literature (see, e.g., [28, 29, 30] and some others.

Experimental Study of the Flooding and Appearance of a Bubble Bed on Top of a Countercurrent Packed-Bed Column

Czech Academy of Sciences Publication Activity Database

Jiřičný, Vladimír; Staněk, Vladimír; Svoboda, Petr; Ondráček, Jakub

2001-01-01

Roč. 40, č. 1 (2001), s. 407-412 ISSN 0888-5885 R&D Projects: GA ČR GA203/97/1174 Institutional research plan: CEZ:AV0Z4072921 Keywords : appearance * bubble-bed * packed bed column Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 1.351, year: 2001

Fecundidad y época de desove del arenque hebra opisthonema libertate (Pisces Clupeidae en el Golfo de Nicoya, Costa Rica. (ING

Directory of Open Access Journals (Sweden)

Jorge A. Rodríguez

2016-03-01

The lineal regression between number of oocites and total length was Y = 722 x - 111,200 (r = 0.5 P < 0,01 and between number of oocites and weight was Y = 395+4,154 ( r = 0,45 P < 0,01 . There was a high variation in the number of oocites with the same lengths or weights. Average relative fecundity by fish gram was 412,16 eggs between 1985-1986

Toeplitz and Hankel operators and Dixmier trances on the unit ball of C-n

Czech Academy of Sciences Publication Activity Database

Engliš, Miroslav; Guo, K.; Zhang, G.

2009-01-01

Roč. 137, č. 11 (2009), s. 3669-3678 ISSN 0002-9939 R&D Projects: GA ČR(CZ) GA201/06/0128 Institutional research plan: CEZ:AV0Z10190503 Keywords : Schatten-von Neumann classes * Macaev classes * trace * Dixmier trace * Toeplitz operators * Hankel operators Subject RIV: BA - General Mathematics Impact factor: 0.640, year: 2009

Toeplitz and Hankel operators and Dixmier trances on the unit ball of C-n

Czech Academy of Sciences Publication Activity Database

Engliš, Miroslav; Guo, K.; Zhang, G.

2009-01-01

Roč. 137, č. 11 (2009), s. 3669-3678 ISSN 0002-9939 R&D Projects: GA ČR(CZ) GA201/06/0128 Institutional research plan: CEZ:AV0Z10190503 Keywords : Schatten- von Neumann classes * Macaev classes * trace * Dixmier trace * Toeplitz operators * Hankel operators Subject RIV: BA - General Mathematics Impact factor: 0.640, year: 2009

System performance with R407A, R407B, R407C compared to R22

DEFF Research Database (Denmark)

Knudsen, Hans Jørgen Høgaard

1997-01-01

been determined.The results show that for R407C both the cooling capacity and the COP are smaller than the cooling capacity and COP for R22. The cooling capacity for R407A and for R407B is lower then the cooling capacity for R22 for brine temperatures less than 0 C and higher than the capacity for R22...... for brine temperatures higher than 0 C. The COP for R407A and 407B are lower than the COP for R22.The volumetriv and isentropic efficiency of the compressor are with mixtures higher than the volumetric and isentropic efficiency with R22.......The paper presents the results obtained by substituting R22 with mixtures of R32/R124/134a (R407A, R407B and R407C) in an existing refrigeration plant. The cooling water flow and cooling water inlet temperature together with the brine flow and brine inlet temperature have been kept on a value...

Comparison of pre-operative dGEMRIC imaging with intra-operative findings in femoroacetabular impingement: preliminary findings

International Nuclear Information System (INIS)

Bittersohl, Bernd; Apprich, Sebastian; Siebenrock, Klaus A.; Mamisch, Tallal Charles; Hosalkar, Harish S.; Werlen, Stefan A.

2011-01-01

To study standard MRI and dGEMRIC in patients with symptomatic FAI undergoing surgical intervention and compare them with intra-operative findings to see if they were corroborative. Sixteen patients with symptomatic FAI that warranted surgical intervention were prospectively studied. All patients underwent plain radiographic series for FAI assessment followed by standard MRI and dGEMRIC. Subsequently, patients were surgically treated with safe dislocation and the joint was evaluated for any macroscopic signs of damaged cartilage. Data were statistically analyzed. A total of 224 zones in 16 patients were evaluated. One hundred and sixteen zones were intra-operatively rated as normal with mean T1 values of 510.1 ms ± 141.2 ms. Eighty zones had evidence of damage with mean T1 values of 453.1 ms ± 113.6 ms. The difference in these T1 values was significant (p = 0.003). Correlation between standard MRI and intra-operative findings was moderate (r = 0.535, p < 0.001). Intra-operative findings revealed more damage than standard MRI. On standard MRI, 68.6% zones were graded normal while 31.4% had evidence of damage. On intra-operative visualization, 56.4% zones were graded normal and 43.6% had evidence of damage. Correlation between dGEMRIC and intra-operative findings turned out to be weak (r = 0.114, p < 0.126). On T1 assessment 31.4% of zones were graded as normal and 68.6% as damaged. dGEMRIC was significantly different between normal and affected cartilage based on intra-operative assessment. The correlation for morphological findings was limited, underestimating defects. By combining morphological with biochemical assessment dGEMRIC may play some role in the future to prognosticate outcomes and facilitate surgical planning and intervention. (orig.)

Preparation and characterization of La{sub 0,60S}r{sub 0},{sub 40}Co{sub 0},{sub 20}Fe{sub 0},{sub 80}O{sub 3-{delta}} powders for intermediate temperature solid oxide fuel cells (ITSOFC) cathode; Preparacao e carcacterizacao de particulados de La{sub 0,60S}r{sub 0},{sub 40}Co{sub 0},{sub 20}Fe{sub 0},{sub 80}O{sub 3-{delta}} para catodos de IT-SOFC

Energy Technology Data Exchange (ETDEWEB)

Vargas, R A; Chiba, R; Bonturim, E; Andreoli, M; Seo, E S.M., [Instituto de Pesquisas Energeticas e Nucleares (CCTM/IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Centro de Ciencia e Tecnologia de Materiais. Lab. de Insumos e Componentes

2009-07-01

Nowadays a material that is studied as cathode in intermediate temperature solid oxide fuel cells (ITSOFC) is the mixing oxide La{sub 0,60S}r{sub 0},{sub 40}Co{sub 0},{sub 20}Fe{sub 0},{sub 80}O{sub 3-{delta}} (LSCF), that possess pseudo-perovskite structure. The objective of this work is to present the physical, chemical and microstructural of LSCF powders characteristics, prepared by the citrate technique. The main analyses utilized were: X-ray diffraction, X-ray fluorescence spectroscopy, laser scattering granulometry, and scanning electron microscopy. The results show that the elimination of organic precursors is important for desired structure formation and that amount of this phase depends on cobalt content. Moreover, the chemical composition is next to stoichiometric calculated (x=0.40 and y=0.80) and the average sizes of particles are adjusted for ceramic suspensions preparation, contributing for the wet powder spraying step conformation. (author)

Naval Reserve Annual Operating Costs

Science.gov (United States)

1975-10-29

C. c ) CPi i 0 0 00 0 le C C.C~r In 1]1 In 00 It .- I to C-38 ’U2 WIX ’W~ - m u. -C-LC m4 C v , v ul FA ?w % -D 1 o r cl jc j, II t %c oK W)i Ir of... platform programs, while Program 11 contains 26 sub-programs each having a separate Reserve program sponsor. The distribution of Program 11 resources is...a mix of specific skills required to bring an active Navy oper-Iating platform to organizational manning. Each SRU is tailored to a specific ship

Nano-Optoelectronic Integration on Silicon

Science.gov (United States)

2012-12-14

hole recombination, a material gain spectrum can be derived as dE EE ffM mcn e g ing in vcr r 22 0 2 2 00 2... ffM mhc en r ing in vcr r sp          (4.3) 48 Figure 4.12 Fitting spontaneous emission spectrum. The experimental

Fatigue cracks in Eurofer 97 steel: Part II. Comparison of small and long fatigue crack growth

Czech Academy of Sciences Publication Activity Database

Kruml, Tomáš; Hutař, Pavel; Náhlík, Luboš; Seitl, Stanislav; Polák, Jaroslav

2011-01-01

Roč. 412, 1 (2011), s. 7-12 ISSN 0022-3115 R&D Projects: GA ČR GA106/09/1954; GA ČR GA101/09/0867 Institutional research plan: CEZ:AV0Z20410507 Keywords : ferritic-martensitic steel * long crack growth * small crack growth * crack closure Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 2.052, year: 2011

Fatigue cracks in Eurofer 97 steel: Part I. Nucleation and small crack growth kinetics

Czech Academy of Sciences Publication Activity Database

Kruml, Tomáš; Polák, Jaroslav

2011-01-01

Roč. 412, 1 (2011), s. 2-6 ISSN 0022-3115 R&D Projects: GA ČR GA106/09/1954; GA ČR GA101/09/0867 Institutional research plan: CEZ:AV0Z20410507 Keywords : ferritic-martensitic steel * low cycle fatigue * small crack growth * fatigue life prediction Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 2.052, year: 2011

Antibound states for a class of one-dimensional Schroedinger Operators

Energy Technology Data Exchange (ETDEWEB)

Angeletti, A [Camerino Univ. (Italy). Ist. di Matematica

1980-11-01

Let delta(x) be the Dirac's delta, q(x) element of L/sup 1/(R) L/sup 2/(R) be a real valued function, and lambda, ..mu.. element of R; we will consider the following class of one-dimensional formal Schroedinger operators on L/sup 2/(R) H(lambda,..mu..) = - (d/sup 2//dx/sup 2/) + lambdadelta(x) + ..mu..q(x). It is known that to the formal operator H(lambda, ..mu..) may be associated a selfadjoint operator H(lambda, ..mu..) on L/sup 2/(R). If q is of finite range, for lambda < 0 and /..mu../ is small enough, we prove that H(lambda,..mu..) has an antibound state; that is the resolvent of H(lambda,..mu..) has a pole on the negative real axis on the second Riemann sheet.

TFTR initial operations

International Nuclear Information System (INIS)

Young, K.M.; Bell, M.; Blanchard, W.R.

1983-11-01

The Tokamak Fusion Test Reactor (TFTR) has operated since December 1982 with ohmically heated plasmas. Routine operation with feedback control of plasma current, position, and density has been obtained for plasmas with I/sub p/ approx. = 800 kA, a = 68 cm, R = 250 cm, and B/sub t/ = 27 kG. A maximum plasma current of 1 MA was achieved with q approx. = 2.5. Energy confinement times of approx. 150 msec were measured for hydrogen and deuterium plasmas with anti n/sub e/ approx. = 2 x 10 13 cm -3 , T/sub e/ (0) approx. = 1.5 keV, T/sub i/ (0) approx. = 1.5 keV, and Z/sub eff/ approx. = 3. The preliminary results suggest a size-cubed scaling from PLT and are consistent with Alcator C scaling where tau approx. nR 2 a. Initial measurements of plasma disruption characteristics indicate current decay rates of approx. 800 kA in 8 ms which is within the TFTR design requirement of 3 MA in 3 ms

1 r urT log ),( r t lim ),( ) ( , urT urrT r r

African Journals Online (AJOL)

Preferred Customer

dθ where u+(z) = max(u(z), 0). The lower order λ of u is given by λ = lim r. urT log. ),(. A sequence {rn} of positive numbers is said to be a sequence of Pólya peaks for T(r, u) of order λ > 0 if there is a sequence {∈n}, ∈n > 0 such that ∈n → 0.

77 FR 31725 - Safety Zone; Belle Pass Dredge Operations, Belle Pass, Mile Marker 1.0 to Mile Marker (−0.2...

Science.gov (United States)

2012-05-30

... Environmental Health Risks and Safety Risks. This rule is not an economically significant rule and does not create an environmental risk to health or risk to safety that may disproportionately affect children. 11...-AA00 Safety Zone; Belle Pass Dredge Operations, Belle Pass, Mile Marker 1.0 to Mile Marker (-0.2), Port...

Peranan Dukungan Organisasi dan Bullying di Tempat Kerja terhadap Komitmen Karyawan pada Organisasi

OpenAIRE

Nesya, Dita Prima

2014-01-01

This study aims to determine the role of organizational support and bullying at workplace toward organizational commitment. Data were collected using organizational commitment scale, organizational support scale and bullying at the workplace scale. This study involved 412 civil servants. The results showed that organizational support and bullying at workplace influence to organizational commitment (R=0.593, R2=0.351, F=110.816; p

The use of patient factors to improve the prediction of operative duration using laparoscopic cholecystectomy.

Science.gov (United States)

Thiels, Cornelius A; Yu, Denny; Abdelrahman, Amro M; Habermann, Elizabeth B; Hallbeck, Susan; Pasupathy, Kalyan S; Bingener, Juliane

2017-01-01

Reliable prediction of operative duration is essential for improving patient and care team satisfaction, optimizing resource utilization and reducing cost. Current operative scheduling systems are unreliable and contribute to costly over- and underestimation of operative time. We hypothesized that the inclusion of patient-specific factors would improve the accuracy in predicting operative duration. We reviewed all elective laparoscopic cholecystectomies performed at a single institution between 01/2007 and 06/2013. Concurrent procedures were excluded. Univariate analysis evaluated the effect of age, gender, BMI, ASA, laboratory values, smoking, and comorbidities on operative duration. Multivariable linear regression models were constructed using the significant factors (p historical surgeon-specific and procedure-specific operative duration. External validation was done using the ACS-NSQIP database (n = 11,842). A total of 1801 laparoscopic cholecystectomy patients met inclusion criteria. Female sex was associated with reduced operative duration (-7.5 min, p < 0.001 vs. male sex) while increasing BMI (+5.1 min BMI 25-29.9, +6.9 min BMI 30-34.9, +10.4 min BMI 35-39.9, +17.0 min BMI 40 + , all p < 0.05 vs. normal BMI), increasing ASA (+7.4 min ASA III, +38.3 min ASA IV, all p < 0.01 vs. ASA I), and elevated liver function tests (+7.9 min, p < 0.01 vs. normal) were predictive of increased operative duration on univariate analysis. A model was then constructed using these predictive factors. The traditional surgical scheduling system was poorly predictive of actual operative duration (R 2  = 0.001) compared to the patient factors model (R 2  = 0.08). The model remained predictive on external validation (R 2  = 0.14).The addition of surgeon as a variable in the institutional model further improved predictive ability of the model (R 2  = 0.18). The use of routinely available pre-operative patient factors improves the prediction of operative

Restart of R reactor at SRP

International Nuclear Information System (INIS)

McDonell, W.R.

1983-01-01

Restart of the Savannah River R-Reactor is an alternative to L-Reactor operation for increased production of defense nuclear material. R-Reactor was shut down in 1964 after 11-years operation and has been on standby for 19 years. This report presents a description of R-Reactor operation to serve as a basis for analysis of environmental impacts after restoration to meet current SRP performance standards. R-Reactor operation would differ from L-Reactor operation principally in discharge and recycle of effluent cooling water to Par Pond, rather than direct discharge to the Savannah River by way of Steel Creek. Significant differences in environmental effects could result. A costly renovation program would be required to restore R-Reactor to operability, and the reactor could not contribute to material production before about 1989

Non-Fermi liquid behaviour in UCoAl: Pressure variations

Czech Academy of Sciences Publication Activity Database

Havela, L.; Honda, F.; Griveau, J.C.; Andreev, Alexander V.; Kolomiets, A.; Sechovský, V.

408-412, - (2006), s. 1316-1319 ISSN 0925-8388 R&D Projects: GA ČR(CZ) GA202/04/1103; GA MŠk(CZ) ME 512 Institutional research plan: CEZ:AV0Z10100520 Keywords : non-Fermi liquid * band metamagnetism Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.250, year: 2006

Floodplain sediments of the 2002 catastrophic flood at the Vltava (Moldau) River and its tributaries: mineralogy, chemical composition, and post-sedimentary evolution

Czech Academy of Sciences Publication Activity Database

Navrátil, Tomáš; Rohovec, Jan; Žák, Karel

2008-01-01

Roč. 56, č. 2 (2008), s. 399-412 ISSN 0943-0105 R&D Projects: GA AV ČR IAA300130505 Institutional research plan: CEZ:AV0Z30130516 Keywords : Vltava (Moldau) River * Berounka River * floodplain sediments * 2002 catastrophic flood (Czech Republic) Subject RIV: DB - Geology ; Mineralogy Impact factor: 1.026, year: 2008

rSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks.

Science.gov (United States)

Guo, Liyuan; Wang, Jing

2018-01-04

Here, we present the updated rSNPBase 3.0 database (http://rsnp3.psych.ac.cn), which provides human SNP-related regulatory elements, element-gene pairs and SNP-based regulatory networks. This database is the updated version of the SNP regulatory annotation database rSNPBase and rVarBase. In comparison to the last two versions, there are both structural and data adjustments in rSNPBase 3.0: (i) The most significant new feature is the expansion of analysis scope from SNP-related regulatory elements to include regulatory element-target gene pairs (E-G pairs), therefore it can provide SNP-based gene regulatory networks. (ii) Web function was modified according to data content and a new network search module is provided in the rSNPBase 3.0 in addition to the previous regulatory SNP (rSNP) search module. The two search modules support data query for detailed information (related-elements, element-gene pairs, and other extended annotations) on specific SNPs and SNP-related graphic networks constructed by interacting transcription factors (TFs), miRNAs and genes. (3) The type of regulatory elements was modified and enriched. To our best knowledge, the updated rSNPBase 3.0 is the first data tool supports SNP functional analysis from a regulatory network prospective, it will provide both a comprehensive understanding and concrete guidance for SNP-related regulatory studies. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

The FOCON96 1.0 computer code

International Nuclear Information System (INIS)

Merle-Szeremeta, A.; Thomassin, A.

1999-01-01

The Institute of Protection and Nuclear Safety (I.P.S.N.) has developed a computer code, FOCON96 1.0 to calculate the dosimetric consequences of atmospheric radioactive releases from nuclear installations after several years of usual operation. This communication describes the principal characteristics of FOCON96 1.0 and its functionalities. The principal elements of a comparison between FOCON96 1.0 and PC-CREAM ( European computer code developed by the N.R.P.B. and answering the same criteria) are given here. (N.C.)

Converting Scoliosis Research Society-24 to Scoliosis Research Society-22r in a Surgical-Range, Medical/Interventional Adolescent Idiopathic Scoliosis Patient Cohort.

Science.gov (United States)

Chen, Antonia F; Bi, Wenzhu; Singhabahu, Dilrukshika; Londino, Joanne; Hohl, Justin; Ward, Maeve; Ward, W Timothy

2013-03-01

Prospective questionnaire administration study. To assess the ability to translate total and domain scores from Scoliosis Research Society (SRS)-24 to SRS-22r in a surgical-range, medical/interventional adolescent idiopathic scoliosis (AIS) patient population. Conversion of SRS-24 to SRS-22r is demonstrated in an operative cohort of patients with AIS, but not in a medical/interventional patient population. We simultaneously administered SRS-24 and SRS-22r questionnaires to 75 surgical-range, medical/interventional AIS patients and compared them. We performed analysis by regression modeling to produce conversion equations from SRS-24 to SRS-22r. The total SRS-24 score for these medical/interventional AIS patients was 92.5 ± 9.45 (mean, 3.9 ± 0.39), and the total SRS-22r score was 93.5 ± 9.63 (mean, 4.3 ± 0.44). The correlation between these 2 groups was fair (R 2 = 0.77) and improved to good when mental health or recall questions were removed. The correlation was also fair for total pain domains (R 2 = 0.73). However, there was poor correlation for general self-image (R 2 = 0.6) and unacceptable for post-treatment self-image (R 2 = 0.01), general function (R 2 = 0.52), activity function (R 2 = 0.56), and satisfaction (R 2 = 0.53). Compared with a published population of operative AIS patients, R 2 values for total SRS-24 scores, pain, general self-image, activity function, and satisfaction were similar (p > .05). The R 2 values for general function and combined general and activity function were significantly different between the operative and medical/interventional cohorts. Scoliosis Research Society-24 can be converted to SRS-22r scores with fair accuracy in the surgical-range, medical/interventional AIS patient population for total score, and total pain domains. The SRS-24 translates unacceptably to the SRS-22r in self-image, function, and satisfaction domains. The SRS-24 to SRS-22r conversion equations are similar to operative AIS patients, except for the

Pyrolaser Operating System

Science.gov (United States)

Roberts, Floyd E., III

1994-01-01

Software provides for control and acquisition of data from optical pyrometer. There are six individual programs in PYROLASER package. Provides quick and easy way to set up, control, and program standard Pyrolaser. Temperature and emisivity measurements either collected as if Pyrolaser in manual operating mode or displayed on real-time strip charts and stored in standard spreadsheet format for posttest analysis. Shell supplied to allow macros, which are test-specific, added to system easily. Written using Labview software for use on Macintosh-series computers running System 6.0.3 or later, Sun Sparc-series computers running Open-Windows 3.0 or MIT's X Window System (X11R4 or X11R5), and IBM PC or compatible computers running Microsoft Windows 3.1 or later.

Bupivacaína racêmica a 0,5% e mistura com excesso enantiomérico de 50% (S75-R25 a 0,5% no bloqueio do plexo braquial para cirurgia ortopédica. Estudo comparativo Bupivacaína racémica a 0,5% y mezcla con exceso enantiomérico del 50% (S75-R25 a 0,5% en el bloqueo del plexo braquial para cirugía ortopédica. Estudio comparativo Comparative study of 0.5% racemic bupivacaine versus enantiomeric mixture (S75-R25 of 0.5% bupivacaine in brachial plexus block for orthopedic surgery

Directory of Open Access Journals (Sweden)

Roberto Tsuneo Cervato Sato

2005-04-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Com a finalidade de encontrar uma droga mais segura que a bupivacaína racêmica, vários estudos foram realizados com seus isômeros. Este estudo tem como objetivo avaliar a eficácia da mistura com excesso enantiomérico de 50% (MEE50% de bupivacaína (S75-R25 a 0,5% comparada a da bupivacaína racêmica a 0,5% no bloqueio do plexo braquial, em pacientes submetidos à cirurgia ortopédica de membros superiores. MÉTODO: Participaram deste estudo, aleatório e duplamente encoberto, 40 pacientes, com idade entre 18 e 90 anos, estado físico ASA I e II, submetidos à cirurgia ortopédica de membros superiores, distribuídos em dois grupos: Grupo R, que recebeu a solução de bupivacaína racêmica a 0,5%, e Grupo L, que recebeu a solução da mistura com excesso enantiomérico de 50% de bupivacaína (S75-R25 a 0,5%, ambas com epinefrina 1:200.000 e num volume de 0,6 mL.kg-1 (3 mg.kg-1, limitados a 40 mL. Foram investigadas as características motoras e/ou sensoriais de cada nervo envolvido (nervos musculocutâneo, radial, mediano, ulnar e cutâneo medial do antebraço, bem como a incidência de efeitos colaterais. RESULTADOS: Não houve diferença estatística significativa em relação aos aspectos demográficos. Os parâmetros hemodinâmicos foram semelhantes entre os grupos, mas a pressão arterial sistólica foi maior no Grupo R. Não houve diferença significativa em relação ao tempo necessário para atingir a maior intensidade dos bloqueios motor e sensitivo. Com uma exceção, a latência do bloqueio motor do grupo muscular inervado pelo n. ulnar foi maior no Grupo L (10,75 versus 14,25 minutos. CONCLUSÕES: Em ambos os grupos foram observados adequados bloqueios motor e sensitivo para a realização da cirurgia, com poucos efeitos colaterais, sugerindo que a mistura com excesso enantiomérico de 50% de bupivacaína (S75-R25 a 0,5% com epinefrina é segura e efetiva para o bloqueio do plexo braquial para

Phylogenetic analysis of freshwater fish trypanosomes from Europe using ssu rRNA gene sequences and random amplification of polymorphic DNA

Czech Academy of Sciences Publication Activity Database

Gibson, W. C.; Lom, Jiří; Pecková, Hana; Ferris, V. R.; Hamilton, P. B.

2005-01-01

Roč. 130, č. 4 (2005), s. 405-412 ISSN 0031-1820 Institutional research plan: CEZ:AV0Z60220518 Keywords : trypanosomes * freshwater fish * phylogeny Subject RIV: EA - Cell Biology Impact factor: 1.703, year: 2005

4-bit digital to analog converter using R-2R ladder and binary weighted resistors

Science.gov (United States)

Diosanto, J.; Batac, M. L.; Pereda, K. J.; Caldo, R.

2017-06-01

The use of a 4-bit digital-to-analog converter using two methods; Binary Weighted Resistors and R-2R Ladder is designed and presented in this paper. The main components that were used in constructing both circuits were different resistor values, operational amplifier (LM741) and single pole double throw switches. Both circuits were designed using MULTISIM software to be able to test the circuit for its ideal application and FRITZING software for the layout designing and fabrication to the printed circuit board. The implementation of both systems in an actual circuit benefits in determining and comparing the advantages and disadvantages of each. It was realized that the binary weighted circuit is more efficient DAC, having lower percentage error of 0.267% compared to R-2R ladder circuit which has a minimum of percentage error of 4.16%.

PEM fuel cells operated at 0% relative humidity in the temperature range of 23-120 oC

International Nuclear Information System (INIS)

Zhang, Jianlu; Tang, Yanghua; Song, Chaojie; Cheng, Xuan; Zhang, Jiujun; Wang, Haijiang

2007-01-01

Operation of a proton exchange membrane (PEM) fuel cell without external humidification (or 0% relative humidity, abbreviated as 0% RH) of the reactant gases is highly desirable, because it can eliminate the gas humidification system and thus decrease the complexity of the PEM fuel cell system and increase the system volume power density (W/l) and weight power density (W/kg). In this investigation, a PEM fuel cell was operated in the temperature range of 23-120 o C, in particular in a high temperature PEM fuel cell operation range of 80-120 o C, with dry reactant gases, and the cell performance was examined according to varying operation parameters. An ac impedance method was used to compare the performance at 0% RH with that at 100% RH; the results suggested that the limited proton transfer process to the Pt catalysts, mainly in the inonomer within the membrane electrode assembly (MEA) could be responsible for the performance drop. It was demonstrated that operating a fuel cell using a commercially available membrane (Nafion (registered) 112) is feasible under certain conditions without external humidification. However, the cell performance at 0% RH decreased with increasing operation temperature and reactant gas flow rate and decreasing operation pressure

Temperature dependent polarization reversal mechanism in 0.94(Bi1/2Na1/2)TiO3-0.06Ba(Zr0.02Ti0.98)O3 relaxor ceramics

Science.gov (United States)

Glaum, Julia; Simons, Hugh; Hudspeth, Jessica; Acosta, Matias; Daniels, John E.

2015-12-01

The temperature at which the electric field induced long-range ordered ferroelectric state undergoes transition into the short-range ordered relaxor state, TF-R, is commonly defined by the onset of strong dispersion of the dielectric permittivity. However, this combined macroscopic property and structural investigation of the polarization reversal process in the prototypical lead-free relaxor 0.94(Bi1/2Na1/2)TiO3-0.06Ba(Zr0.02Ti0.98)O3 reveals that an applied electric field can trigger depolarization and onset of relaxor-like behavior well below TF-R. The polarization reversal process can as such be described as a combination of (1) ferroelectric domain switching and (2) a reversible phase transition between two polar ferroelectric states mediated by a non-polar relaxor state. Furthermore, the threshold fields of the second, mediated polarization reversal mechanism depend strongly on temperature. These results are concomitant with a continuous ferroelectric to relaxor transition occurring over a broad temperature range, during which mixed behavior is observed. The nature of polarization reversal can be illustrated in electric-field-temperature (E-T) diagrams showing the electric field amplitudes associated with different polarization reversal processes. Such diagrams are useful tools for identifying the best operational temperature regimes for a given composition in actuator applications.

Effect of an EBM course in combination with case method learning sessions: an RCT on professional performance, job satisfaction, and self-efficacy of occupational physicians.

Science.gov (United States)

Hugenholtz, Nathalie I R; Schaafsma, Frederieke G; Nieuwenhuijsen, Karen; van Dijk, Frank J H

2008-10-01

An intervention existing of an evidence-based medicine (EBM) course in combination with case method learning sessions (CMLSs) was designed to enhance the professional performance, self-efficacy and job satisfaction of occupational physicians. A cluster randomized controlled trial was set up and data were collected through questionnaires at baseline (T0), directly after the intervention (T1) and 7 months after baseline (T2). The data of the intervention group [T0 (n = 49), T1 (n = 31), T2 (n = 29)] and control group [T0 (n = 49), T1 (n = 28), T2 (n = 28)] were analysed in mixed model analyses. Mean scores of the perceived value of the CMLS were calculated in the intervention group. The overall effect of the intervention over time comparing the intervention with the control group was statistically significant for professional performance (p Job satisfaction and self-efficacy changes were small and not statistically significant between the groups. The perceived value of the CMLS to gain new insights and to improve the quality of their performance increased with the number of sessions followed. An EBM course in combination with case method learning sessions is perceived as valuable and offers evidence to enhance the professional performance of occupational physicians. However, it does not seem to influence their self-efficacy and job satisfaction.

Hazard and operability study (Haz Op) of the 2 MW IEA-R1 reactor startup procedures

International Nuclear Information System (INIS)

Sauer, Maria E.L.J.; Correa, Francisco; Sara Neto, Antonio J.; Costa, Carlos A.R. da; Santos, Cilas C. dos; Cardenas, Jose P.N.; Berretta, Jose R.; Neves Conti, Thadeu das

1997-01-01

This work presents the Hazard and Operability Study (Haz Op) applied to startup procedures of the 2 MW IEA-R1 research reactor, at IPEN/CNEN-S P. The Haz Op was developed by reviewing the procedures of the installation startup, in order to identify hazards and/or operational problems caused by deviations in the execution of these routines. This paper summarizes this study. describing some potential problems of relevant importance to safety as well as preventives and/or correctives measures to avoid their occurrence. Besides, an benefits evaluation and the technique limitations is made. (author). 5 refs., 1 tab

Renormalizing the kinetic energy operator in elementary quantum mechanics

Energy Technology Data Exchange (ETDEWEB)

Coutinho, F A B [Faculdade de Medicina, Universidade de Sao Paulo e LIM 01-HCFMUSP, 05405-000 Sao Paulo (Brazil); Amaku, M [Faculdade de Medicina Veterinaria e Zootecnia, Universidade de Sao Paulo, 05508-970 Sao Paulo (Brazil)], E-mail: coutinho@dim.fm.usp.br

2009-09-15

In this paper, we consider solutions to the three-dimensional Schroedinger equation of the form {psi}(r) = u(r)/r, where u(0) {ne} 0. The expectation value of the kinetic energy operator for such wavefunctions diverges. We show that it is possible to introduce a potential energy with an expectation value that also diverges, exactly cancelling the kinetic energy divergence. This renormalization procedure produces a self-adjoint Hamiltonian. We solve some problems with this new Hamiltonian to illustrate its usefulness.

Renormalizing the kinetic energy operator in elementary quantum mechanics

International Nuclear Information System (INIS)

Coutinho, F A B; Amaku, M

2009-01-01

In this paper, we consider solutions to the three-dimensional Schroedinger equation of the form ψ(r) = u(r)/r, where u(0) ≠ 0. The expectation value of the kinetic energy operator for such wavefunctions diverges. We show that it is possible to introduce a potential energy with an expectation value that also diverges, exactly cancelling the kinetic energy divergence. This renormalization procedure produces a self-adjoint Hamiltonian. We solve some problems with this new Hamiltonian to illustrate its usefulness.

A universal operator on the Gurarii space

Czech Academy of Sciences Publication Activity Database

Garbulińska-Węgrzyn, J.; Kubiś, Wieslaw

2015-01-01

Roč. 73, č. 1 (2015), s. 143-158 ISSN 0379-4024 R&D Projects: GA ČR(CZ) GAP201/12/0290 Institutional support: RVO:67985840 Keywords : almost isometry * Gurariî * isometrically universal operator Subject RIV: BA - General Mathematics Impact factor: 0.464, year: 2015 http://www.mathjournals.org/jot/2015-073-001/2015-073-001-007.html

Observation of the isospin-violating decay {ital D}{sub {ital s}}{sup *+}{r_arrow}{ital D}{sup +}{sub {ital s}}{pi}{sup 0}

Energy Technology Data Exchange (ETDEWEB)

Gronberg, J.; Korte, C.M.; Kutschke, R.; Menary, S.; Morrison, R.J.; Nakanishi, S.; Nelson, H.N.; Nelson, T.K.; Qiao, C.; Richman, J.D.; Roberts, D.; Ryd, A.; Tajima, H.; Witherell, M.S.; Balest, R.; Cho, K.; Ford, W.T.; Lohner, M.; Park, H.; Rankin, P.; Smith, J.G.; Alexander, J.P.; Bebek, C.; Berger, B.E.; Berkelman, K.; Bloom, K.; Browder, T.E.; Cassel, D.G.; Cho, H.A.; Coffman, D.M.; Crowcroft, D.S.; Dickson, M.; Drell, P.S.; Dumas, D.J.; Ehrlich, R.; Elia, R.; Gaidarev, P.; Garcia-Sciveres, M.; Gittelman, B.; Gray, S.W.; Hartill, D.L.; Heltsley, B.K.; Henderson, S.; Jones, C.D.; Jones, S.L.; Kandaswamy, J.; Katayama, N.; Kim, P.C.; Kreinick, D.L.; Lee, T.; Liu, Y.; Ludwig, G.S.; Masui, J.; Mevissen, J.; Mistry, N.B.; Ng, C.R.; Nordberg, E.; Patterson, J.R.; Peterson, D.; Riley, D.; Soffer, A.; Avery, P.; Freyberger, A.; Lingel, K.; Prescott, C.; Rodriguez, J.; Yang, S.; Yelton, J.; Brandenburg, G.; Cinabro, D.; Liu, T.; Saulnier, M.; Wilson, R.; Yamamoto, H.; Bergfeld, T.; Eisenstein, B.I.; Ernst, J.; Gladding, G.E.; Gollin, G.D.; Palmer, M.; Selen, M.; Thaler, J.J.; Edwards, K.W.; McLean, K.W.; Ogg, M.; Bellerive, A.; Britton, D.I.; Hyatt, E.R.F.; Janicek, R.; MacFarlane, D.B.; Patel, P.M.; Spaan, B.; Sadoff, A.J.; Ammar, R.; Baringer, P.; Bean, A.; Besson, D.; Coppage, D.; Copty, N.; Davis, R.; Hancock, N.; Kotov, S.; Kravchenko, I.; Kwak, N.; Kubota, Y.; Lattery, M.; Momayezi, M.; Nelson, J.K.; Patton, S.; Poling, R.; Savinov, V.; Schrenk, S.; Wang, R.; Alam, M.S.; Kim, I.J.; Ling, Z.; Mahmood, A.H.; O`Neill, J.J.; Severini, H.; Sun, C.R.; Wappler, F.; Crawford, G.; Fulton, R.; Fujino, D.; Gan, K.K.; Honscheid, K.; Kagan, H.; Kass, R.; Lee, J.; Sung, M.; White, C.; Wolf, A.; Zoeller, M.M.; Fu, X.; Nemati, B.; Ross, W.R.; Skubic, P.; Wood, M.; Bishai, M.; Fast, J.; Gerndt, E.; Hinson, J.W.; Miao, T.; Miller, D.H.; Modesitt, M.; Shibata, E.I.; Shipsey, I.P.J.; Wang, P.N.; Gibbons, L.; Johnson, S.D.; Kwon, Y.; Roberts, S.; Thorndike, E.H.; Coan, T.; (CLEO Co...

1995-10-30

Using data collected with the CLEO II detector, we have observed the isospin-violating decay {ital D}{sub {ital s}}{sup *+}{r_arrow}{ital D}{sup +}{sub {ital s}}{pi}{sup 0}. The decay rate for this mode, relative to the dominant radiative decay, is found to be {Gamma}({ital D}{sub {ital s}}{sup *+}{r_arrow}{ital D}{sup +}{sub {ital s}}{pi}{sup 0}) /{Gamma}({ital D}{sub {ital s}}{sup *+}{r_arrow}{ital D}{sup +}{ital s}{gamma}) =0.062{sub {minus}0.018}{sup +0.020}{plus_minus}0.022. {copyright} {ital 1995} {ital The} {ital American} {ital Physical} {ital Society}.

The future of the IPR-R1 TRIGA MARK I reactor after 48 years operation

International Nuclear Information System (INIS)

Maretti, Fausto Junior; Sette Camara, Luiz Otavio I.; Oliveira, Paulo Fernando

2008-01-01

The TRIGA Mark I IPR-R1 Reactor operates in the Nuclear Technology Development Center/ Brazilian Committion for Nuclear Energy (CDTN/CNEN), originally Institute of Radioactive Researches, in Belo Horizonte, Minas Gerais, since November 6, 1960. Initially it operated for isotope production for different uses, being later used in wide scale for another purposes as analyses for activation with neutrons and training of nuclear power plants operators. Dozens of degree theses were also developed with the use of the reactor. Along the years, several improvements were introduced in the reactor and its auxiliary systems, with the purpose to provide better use of the facilities and with the objective to increase the safety in the operation. The reactor is ready right now to operate at 250 kW, and for sure the nuclear applications programmed will be improved. The Operation Manual and the Safety Analysis report were already modified, as well as the Emergency Plan and the relative procedures to the same. After the tests at the end of 2008, the reactor will already be operating in the new power. This work presents a description of the several accomplishments of the last years and comments about the possibility of new uses for the reactor in the several areas of nuclear applications and some of the experiments and tests results during the upgrading program. (authors)

Isolated Gramicidin Peptides Probed by IR Spectroscopy

Czech Academy of Sciences Publication Activity Database

Rijs, A. M.; Kabeláč, Martin; Abo-Riziq, A.; Hobza, Pavel; de Vries, M. S.

2011-01-01

Roč. 12, č. 10 (2011), s. 1816-1821 ISSN 1439-4235 R&D Projects: GA MŠk LC512; GA AV ČR IAA400550808 Institutional research plan: CEZ:AV0Z40550506 Keywords : density functional calculations * gramicidin * IR spectroscopy * protein folding Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.412, year: 2011

An analysis of general surgery-related complications in a series of 412 minilaparotomic anterior lumbosacral procedures.

Science.gov (United States)

Kang, Byung-Uk; Choi, Won-Chul; Lee, Sang-Ho; Jeon, Sang Hyeop; Park, Jong Dae; Maeng, Dae Hyeon; Choi, Young-Geun

2009-01-01

Anterior lumbar surgery is associated with certain perioperative visceral and vascular complications. The aim of this study was to document all general surgery-related adverse events and complications following minilaparotomic retroperitoneal lumbar procedures and to discuss strategies for their management or prevention. The authors analyzed data obtained in 412 patients who underwent anterior lumbosacral surgery between 2003 and 2005. The series comprised 114 men and 298 women whose mean age was 56 years (range 34-79 years). Preoperative diagnoses were as follows: isthmic spondylolisthesis (32%), degenerative spondylolisthesis (24%), instability/stenosis (15%), degenerative disc disease (15%), failed-back surgery syndrome (7%), and lumbar degenerative kyphosis or scoliosis (7%). A single level was exposed in 264 patients (64%), 2 in 118 (29%), and 3 or 4 in 30 (7%). The average follow-up period was 16 months. Overall, 52 instances of complications and adverse events occurred in 50 patients (12.1%), including sympathetic dysfunction in 25 (6.06%), vascular injury repaired with/without direct suture in 12 (2.9%), ileus lasting > 3 days in 5 (1.2%), pleural effusion in 4 (0.97%), wound dehiscence in 2 (0.49%), symptomatic retroperitoneal hematoma in 2 (0.49%), angina in 1 (0.24%), and bowel laceration in 1 patient (0.24%). There was no instance of retrograde ejaculation in male patients, and most complications had no long-term sequelae. This report presents a detailed analysis of complications related to anterior lumbar surgery. Although the incidence of complications appears low considering the magnitude of the procedure, surgeons should be aware of these potential complications and their management.

Transition operators in acoustic-wave diffraction theory. I - General theory. II - Short-wavelength behavior, dominant singularities of Zk0 and Zk0 exp -1

Science.gov (United States)

Hahne, G. E.

1991-01-01

A formal theory of the scattering of time-harmonic acoustic scalar waves from impenetrable, immobile obstacles is established. The time-independent formal scattering theory of nonrelativistic quantum mechanics, in particular the theory of the complete Green's function and the transition (T) operator, provides the model. The quantum-mechanical approach is modified to allow the treatment of acoustic-wave scattering with imposed boundary conditions of impedance type on the surface (delta-Omega) of an impenetrable obstacle. With k0 as the free-space wavenumber of the signal, a simplified expression is obtained for the k0-dependent T operator for a general case of homogeneous impedance boundary conditions for the acoustic wave on delta-Omega. All the nonelementary operators entering the expression for the T operator are formally simple rational algebraic functions of a certain invertible linear radiation impedance operator which maps any sufficiently well-behaved complex-valued function on delta-Omega into another such function on delta-Omega. In the subsequent study, the short-wavelength and the long-wavelength behavior of the radiation impedance operator and its inverse (the 'radiation admittance' operator) as two-point kernels on a smooth delta-Omega are studied for pairs of points that are close together.

Compactness of the Hardy Operator and its Limiting Case

Czech Academy of Sciences Publication Activity Database

Gogatishvili, Amiran; Kufner, Alois; Persson, L. E.; Wedestig, A.

2006-01-01

Roč. 32, č. 1 (2006), s. 21-35 ISSN 0250-3255 R&D Projects: GA ČR(CZ) GA201/03/0671 Institutional research plan: CEZ:AV0Z10190503 Keywords : Hardy operator * compactness * Hardy´s inequality Subject RIV: BA - General Mathematics

Bio-fuels - biohazard

International Nuclear Information System (INIS)

Slovak, K.

2008-01-01

Politicians have a clear explanation for growing commodity prices. It is all the fault of speculators. It is easy to point the finger at an imaginary enemy. It is more difficult and from the point of view of a political career suicidal to admit one's mistakes. And there are reasons for remorse. According to studies prepared by the OECD and the World Bank bio-fuels are to be blame for high food prices. The bio-fuel boom that increases the demand for agro-commodities has been created by politicians offering generous subsidies. And so farming products do not end up on the table, but in the fuel tanks of cars in the form of additives. And their only efficiency is that they make food more expensive. The first relevant indication that environmentalist tendencies in global politics have resulted in shortages and food price increases can be found in a confidential report prepared by the World Bank. Parts of the report were leaked to the media last month. According to this information growing bio-fuel production has resulted in a food price increase by 75%. The theory that this development was caused by speculators and Chinese and Indian demand received a serious blow. And the OECD report definitely contradicted the excuse used by the politicians. According to the report one of the main reasons for growing food prices are generously subsidized bio-fuels. Their share of the increase of demand for agro-commodities in 2005 -2007 was 60% according to the study. (author)

Tetragonal-to-Tetragonal Phase Transition in Lead-Free (KxNa1−xNbO3 (x = 0.11 and 0.17 Crystals

Directory of Open Access Journals (Sweden)

Dabin Lin

2014-06-01

Full Text Available Lead free piezoelectric crystals of (KxNa1−xNbO3 (x = 0.11 and 0.17 have been grown by the modified Bridgman method. The structure and chemical composition of the obtained crystals were determined by X-ray diffraction (XRD and electron probe microanalysis (EPMA. The domain structure evolution with increasing temperature for (KxNa1−xNbO3 (x = 0.11 and 0.17 crystals was observed using polarized light microscopy (PLM, where distinguished changes of the domain structures were found to occur at 400 °C and 412 °C respectively, corresponding to the tetragonal to tetragonal phase transition temperatures. Dielectric measurements performed on (K0.11Na0.89NbO3 crystals exhibited tetragonal to tetragonal and tetragonal to cubic phase transitions temperatures at 405 °C and 496 °C, respectively.

Some problems in operator theory on bounded symmetric domains

Czech Academy of Sciences Publication Activity Database

Engliš, Miroslav

2004-01-01

Roč. 81, č. 1 (2004), s. 51-71 ISSN 0167-8019. [Representations of Lie groups, harmonic analysis on homogeneous spaces and quantization. Leiden, 07.12.2002-13.12.2002] R&D Projects: GA ČR GA201/03/0041 Institutional research plan: CEZ:AV0Z1019905 Keywords : homogeneous multiplication operators * bounded symmetric domains Subject RIV: BA - General Mathematics Impact factor: 0.354, year: 2004

Network configuration of global R&D networks

DEFF Research Database (Denmark)

Hansen, Zaza Nadja Lee; Srai, Jagjit Singh

2011-01-01

, network configuration of global R&D has tended to focus on strategic elements with limited attention given operational effectiveness, or to interfaces with downstream manufacturing operations. Within OM literature, the drivers of configuration of global networks within, engineering, production, supply...... to R&D networks emerged, e.g. product features were more prominent in R&D networks. Furthermore, the study has shown extensive interaction with other operations, including many downstream manufacturing operations. By extending the OM configuration concepts to the configuration of R&D networks......Companies are increasingly globalising their R&D activities, both within the firms and with external partners, with consequent implications for their interaction with manufacturing operations. Previous research in R&D networks has focused on coordination, governance and support elements. However...

Features of magnetic and thermal properties of R(Co{sub 1−x}Fe{sub x}){sub 2} (x≤0.16) quasibinary compounds with R=Dy, Ho, Er

Energy Technology Data Exchange (ETDEWEB)

Anikin, Maksim; Tarasov, Evgeniy; Kudrevatykh, Nikolay [Institute of Natural Sciences, Ural Federal University, Ekaterinburg 620002 (Russian Federation); Inishev, Aleksander [Institute of Metal Physics, Ekaterinburg 620137 (Russian Federation); Semkin, Mikhail; Volegov, Aleksey; Zinin, Aleksander [Institute of Natural Sciences, Ural Federal University, Ekaterinburg 620002 (Russian Federation)

2016-11-15

In this work the results of measurements of high field susceptibility, paraprocess susceptibility and thermal properties of R(Co{sub 1−x}Fe{sub x}){sub 2} intermetallic compounds (R=Dy, Ho, Er and x=(0−0.16)) are presented (heat capacity and magnetocaloric effect (MCE)). A magnetic structure of the Ho(Co{sub 0.88}Fe{sub 0.12}){sub 2} at 293 K and 78 K was studied by neutron powder diffraction. Some peculiarities of a high-field susceptibility were revealed at low temperatures and around the Curie point (T{sub C}). In temperature range lower than T{sub C} by (100–150) K, magnetic contributions to a zero-field heat capacity were found. Studying MCE in wide temperatures range, the large change of the entropy magnetic contribution (∆S) was observed which correlates with ∆T phenomenon. In particular, for the Er(Co{sub 0.84}Fe{sub 0.16}){sub 2} compound the ∆S value at low temperatures is six times higher than that at Curie point. The possible reasons of such behavior were discussed. - Highlights: • Magnetic and magnetocaloric properties of R(Co–Fe){sub 2} compounds have been studied. • Fe introduction induces the disorientation effect in Ho-ions magnetic ordering. • Emergence of magnetic contribution to a heat capacity at temperatures less T{sub C}. • The existence of a broad maximum on a temperature dependence of the MCE. • Direct MCE measurements at magnetic field of (0–17.5) kOe have been performed.

The one-sided Ap conditions and local maximal operator

Czech Academy of Sciences Publication Activity Database

Bernardis, A.L.; Gogatishvili, Amiran; Martin-Reyes, F. J.; Ortega Salvador, P.; Pick, L.

Roč. 55, č. 1 ( 2012 ), s. 79-104 ISSN 0013-0915 R&D Projects: GA ČR GA201/08/0383; GA ČR GA201/05/2033 Institutional research plan: CEZ:AV0Z10190503 Keywords : one-sided Ap conditions * one-sided local maximal operator * quasi-Banach function spaces * variable-exponent Lebesgue spaces Subject RIV: BA - General Mathematics Impact factor: 0.561, year: 2012 http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8477114&fulltextType=RA&fileId=S0013091510000635

Magnetic propertiesof Lu.sub.2./sub.Fe.sub.16./sub.X (X = Fe, Ni, Cr, Si) intermetallics under high hydrostatic pressure

Czech Academy of Sciences Publication Activity Database

Kamarád, Jiří; Andreev, Alexander V.; Machátová, Zuzana; Arnold, Zdeněk

408-412, - (2006), s. 151-154 ISSN 0925-8388 R&D Projects: GA ČR(CZ) GA202/02/0739; GA MŠk(CZ) ME 495 Institutional research plan: CEZ:AV0Z10100521 Keywords : intermetallic compounds * Lu 2 Fe 17 * magnetic properties * high pressure Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.250, year: 2006