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Sample records for biodosimetry ldrd project

  1. FY05 LDRD Final Report Molecular Radiation Biodosimetry LDRD Project Tracking Code: 04-ERD-076

    Energy Technology Data Exchange (ETDEWEB)

    Jones, I M; A.Coleman, M; Lehmann, J; Manohar, C F; Marchetti, F; Mariella, R; Miles, R; Nelson, D O; Wyrobek, A J

    2006-02-03

    been, these methods are not suitable. The best current option for triage radiation biodosimetry is self-report of time to onset of emesis after the event, a biomarker that is subject to many false positives. The premise of this project is that greatly improved radiation dosimetry can be achieved by research and development directed toward detection of molecular changes induced by radiation in cells or other biological materials. Basic research on the responses of cells to radiation at the molecular level, particularly of message RNA and proteins, has identified biomolecules whose levels increase (or decrease) as part of cellular responses to radiation. Concerted efforts to identify markers useful for triage and clinical applications have not been reported as yet. Such studies would scan responses over a broad range of doses, below, at and above the threshold of clinical significance in the first weeks after exposure, and would collect global proteome and/or transcriptome information on all tissue samples accessible to either first responders or clinicians. For triage, the goal is to identify those needing medical treatment. Treatment will be guided by refined dosimetry. Achieving this goal entails determining whether radiation exposure was below or above the threshold of concern, using one sample collected within days of an event, with simple devices that first responders either use or distribute for self-testing. For the clinic, better resolution of dose and tissue damage is needed to determine the nature and time sensitivity of therapy, but multiple sampling times may be acceptable and clinical staff and equipment can be utilized. Two complementary areas of research and development are needed once candidate biomarkers are identified, validation of the biomarker responses and validation of devices/instrumentation for detection of responses. Validation of biomarkers per se is confirmation that the dose, time, and tissue specific responses meet the reporting

  2. FY 2014 LDRD Annual Report Project Summaries

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    Tomchak, Dena [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-02-01

    The FY 2014 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support future DOE missions and national research priorities. LDRD is essential to INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enahnces technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

  3. Idaho National Laboratory Annual Report FY 2013 LDRD Project Summaries

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    Dena Tomchak

    2014-03-01

    The FY 2013 LDRD Annual Report is a compendium of the diverse research performed to develop and ensure the INL’s technical capabilities support the current and future DOE missions and national research priorities. LDRD is essential to INL—it provides a means for the Laboratory to maintain scientific and technical vitality while funding highly innovative, high-risk science and technology research and development (R&D) projects. The program enhances technical capabilities at the Laboratory, providing scientific and engineering staff with opportunities to explore proof-of-principle ideas, advanced studies of innovative concepts, and preliminary technical analyses. Established by Congress in 1991, the LDRD Program proves its benefit each year through new programs, intellectual property, patents, copyrights, national and international awards, and publications.

  4. LDRD project 151362 : low energy electron-photon transport.

    Energy Technology Data Exchange (ETDEWEB)

    Kensek, Ronald Patrick; Hjalmarson, Harold Paul; Magyar, Rudolph J.; Bondi, Robert James; Crawford, Martin James

    2013-09-01

    At sufficiently high energies, the wavelengths of electrons and photons are short enough to only interact with one atom at time, leading to the popular %E2%80%9Cindependent-atom approximation%E2%80%9D. We attempted to incorporate atomic structure in the generation of cross sections (which embody the modeled physics) to improve transport at lower energies. We document our successes and failures. This was a three-year LDRD project. The core team consisted of a radiation-transport expert, a solid-state physicist, and two DFT experts.

  5. THz transceiver characterization : LDRD project 139363 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Nordquist, Christopher Daniel; Wanke, Michael Clement; Cich, Michael Joseph; Reno, John Louis; Fuller, Charles T.; Wendt, Joel Robert; Lee, Mark; Grine, Albert D.

    2009-09-01

    LDRD Project 139363 supported experiments to quantify the performance characteristics of monolithically integrated Schottky diode + quantum cascade laser (QCL) heterodyne mixers at terahertz (THz) frequencies. These integrated mixers are the first all-semiconductor THz devices to successfully incorporate a rectifying diode directly into the optical waveguide of a QCL, obviating the conventional optical coupling between a THz local oscillator and rectifier in a heterodyne mixer system. This integrated mixer was shown to function as a true heterodyne receiver of an externally received THz signal, a breakthrough which may lead to more widespread acceptance of this new THz technology paradigm. In addition, questions about QCL mode shifting in response to temperature, bias, and external feedback, and to what extent internal frequency locking can improve stability have been answered under this project.

  6. Selected Examples of LDRD Projects Supporting Test Ban Treaty Verification and Nonproliferation

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Al-Ayat, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Walter, W. R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-02-23

    The Laboratory Directed Research and Development (LDRD) Program at the DOE National Laboratories was established to ensure the scientific and technical vitality of these institutions and to enhance the their ability to respond to evolving missions and anticipate national needs. LDRD allows the Laboratory directors to invest a percentage of their total annual budget in cutting-edge research and development projects within their mission areas. We highlight a selected set of LDRD-funded projects, in chronological order, that have helped provide capabilities, people and infrastructure that contributed greatly to our ability to respond to technical challenges in support of test ban treaty verification and nonproliferation.

  7. Final report on LDRD project : advanced optical trigger systems.

    Energy Technology Data Exchange (ETDEWEB)

    Roose, Lars D.; Hadley, G. Ronald; Mar, Alan; Serkland, Darwin Keith; Geib, Kent Martin; Sullivan, Charles Thomas; Keeler, Gordon Arthur; Bauer, Thomas M. (LMATA Government Services, LLC., Albuquerque, NM); Peake, Gregory Merwin; Loubriel, Guillermo Manuel; Montano, Victoria A. (LMATA Government Services, LLC., Albuquerque, NM)

    2008-09-01

    are difficult to scale and manufacture with the required uniformity. As a promising alternative to multiple discrete edge-emitting lasers, a single wafer of vertical-cavity surface-emitting lasers (VCSELs) can be lithographically patterned to achieve the desired layout of parallel line-shaped emitters, in which adjacent lasers utilize identical semiconductor material and thereby achieve a degree of intrinsic optical uniformity. Under this LDRD project, we have fabricated arrays of uncoupled circular-aperture VCSELs to approximate a line-shaped illumination pattern, achieving optical fill factors ranging from 2% to 30%. We have applied these VCSEL arrays to demonstrate single and dual parallel line-filament triggering of PCSS devices. Moreover, we have developed a better understanding of the illumination requirements for stable triggering of multiple-filament PCSS devices using VCSEL arrays. We have found that reliable triggering of multiple filaments requires matching of the turn-on time of adjacent VCSEL line-shaped-arrays to within approximately 1 ns. Additionally, we discovered that reliable triggering of PCSS devices at low voltages requires more optical power than we obtained with our first generation of VCSEL arrays. A second generation of higher-power VCSEL arrays was designed and fabricated at the end of this LDRD project, and testing with PCSS devices is currently underway (as of September 2008).

  8. Final report of LDRD project: Electromagnetic impulse radar for detection of underground structures

    Energy Technology Data Exchange (ETDEWEB)

    Loubriel, G.; Aurand, J.; Buttram, M.; Zutavern, F.; Brown, D.; Helgeson, W.

    1998-03-01

    This report provides a summary of the LDRD project titled: Electromagnetic impulse radar for the detection of underground structures. The project met all its milestones even with a tight two year schedule and total funding of $400 k. The goal of the LDRD was to develop and demonstrate a ground penetrating radar (GPR) that is based on high peak power, high repetition rate, and low center frequency impulses. The idea of this LDRD is that a high peak power, high average power radar based on the transmission of short impulses can be utilized effect can be utilized for ground penetrating radar. This direct time-domain system the authors are building seeks to increase penetration depth over conventional systems by using: (1) high peak power, high repetition rate operation that gives high average power, (2) low center frequencies that better penetrate the ground, and (3) short duration impulses that allow for the use of downward looking, low flying platforms that increase the power on target relative to a high flying platform. Specifically, chirped pulses that are a microsecond in duration require (because it is difficult to receive during transmit) platforms above 150 m (and typically 1 km) while this system, theoretically could be at 10 m above the ground. The power on target decays with distance squared so the ability to use low flying platforms is crucial to high penetration. Clutter is minimized by time gating the surface clutter return. Short impulses also allow gating (out) the coupling of the transmit and receive antennas.

  9. Predicting Function of Biological Macromolecules: A Summary of LDRD Activities: Project 10746

    Energy Technology Data Exchange (ETDEWEB)

    FRINK, LAURA J. D.; REMPE, SUSAN L.; MEANS, SHAWN A.; STEVENS, MARK J.; CROZIER, PAUL S.; MARTIN, MARCUS G.; SEARS, MARK P.; HJALMARSON, HAROLD P.

    2002-11-01

    This LDRD project has involved the development and application of Sandia's massively parallel materials modeling software to several significant biophysical systems. They have been successful in applying the molecular dynamics code LAMMPS to modeling DNA, unstructured proteins, and lipid membranes. They have developed and applied a coupled transport-molecular theory code (Tramonto) to study ion channel proteins with gramicidin A as a prototype. they have used the Towhee configurational bias Monte-Carlo code to perform rigorous tests of biological force fields. they have also applied the MP-Sala reacting-diffusion code to model cellular systems. Electroporation of cell membranes has also been studied, and detailed quantum mechanical studies of ion solvation have been performed. In addition, new molecular theory algorithms have been developed (in FasTram) that may ultimately make protein solvation calculations feasible on workstations. Finally, they have begun implementation of a combined molecular theory and configurational bias Monte-Carlo code. They note that this LDRD has provided a basis for several new internal (e.g. several new LDRD) and external (e.g. 4 NIH proposals and a DOE/Genomes to Life) proposals.

  10. FPGAs in High Perfomance Computing: Results from Two LDRD Projects.

    Energy Technology Data Exchange (ETDEWEB)

    Underwood, Keith D; Ulmer, Craig D.; Thompson, David; Hemmert, Karl Scott

    2006-11-01

    Field programmable gate arrays (FPGAs) have been used as alternative computational de-vices for over a decade; however, they have not been used for traditional scientific com-puting due to their perceived lack of floating-point performance. In recent years, there hasbeen a surge of interest in alternatives to traditional microprocessors for high performancecomputing. Sandia National Labs began two projects to determine whether FPGAs wouldbe a suitable alternative to microprocessors for high performance scientific computing and,if so, how they should be integrated into the system. We present results that indicate thatFPGAs could have a significant impact on future systems. FPGAs have thepotentialtohave order of magnitude levels of performance wins on several key algorithms; however,there are serious questions as to whether the system integration challenge can be met. Fur-thermore, there remain challenges in FPGA programming and system level reliability whenusing FPGA devices.4 AcknowledgmentArun Rodrigues provided valuable support and assistance in the use of the Structural Sim-ulation Toolkit within an FPGA context. Curtis Janssen and Steve Plimpton provided valu-able insights into the workings of two Sandia applications (MPQC and LAMMPS, respec-tively).5

  11. Validated modeling of distributed energy resources at distribution voltages : LDRD project 38672.

    Energy Technology Data Exchange (ETDEWEB)

    Ralph, Mark E.; Ginn, Jerry W.

    2004-03-01

    A significant barrier to the deployment of distributed energy resources (DER) onto the power grid is uncertainty on the part of utility engineers regarding impacts of DER on their distribution systems. Because of the many possible combinations of DER and local power system characteristics, these impacts can most effectively be studied by computer simulation. The goal of this LDRD project was to develop and experimentally validate models of transient and steady state source behavior for incorporation into utility distribution analysis tools. Development of these models had not been prioritized either by the distributed-generation industry or by the inverter industry. A functioning model of a selected inverter-based DER was developed in collaboration with both the manufacturer and industrial power systems analysts. The model was written in the PSCAD simulation language, a variant of the ElectroMagnetic Transients Program (EMTP), a code that is widely used and accepted by utilities. A stakeholder team was formed and a methodology was established to address the problem. A list of detailed DER/utility interaction concerns was developed and prioritized. The list indicated that the scope of the problem significantly exceeded resources available for this LDRD project. As this work progresses under separate funding, the model will be refined and experimentally validated. It will then be incorporated in utility distribution analysis tools and used to study a variety of DER issues. The key next step will be design of the validation experiments.

  12. Recent developments in biodosimetry

    International Nuclear Information System (INIS)

    This report reviews recent developments in biodosimetry (1989-1993), and presents a comparative study of the existing techniques and their future prospects. The report summarizes the sensitivity, reproducibility, limiting dose, dose-rate, energy, linear energy transfer (LET) responses, sources of variability and uncertainty, and other practical aspects of each bio-indicator. The strengths and weaknesses of each approach are evaluated on the basis of a set of common criteria for particular applications. (author). 155 refs., 15 tabs

  13. FY08 LDRD Final Report A New Method for Wave Propagation in Elastic Media LDRD Project Tracking Code: 05-ERD-079

    Energy Technology Data Exchange (ETDEWEB)

    Petersson, A

    2009-01-29

    The LDRD project 'A New Method for Wave Propagation in Elastic Media' developed several improvements to the traditional finite difference technique for seismic wave propagation, including a summation-by-parts discretization which is provably stable for arbitrary heterogeneous materials, an accurate treatment of non-planar topography, local mesh refinement, and stable outflow boundary conditions. This project also implemented these techniques in a parallel open source computer code called WPP, and participated in several seismic modeling efforts to simulate ground motion due to earthquakes in Northern California. This research has been documented in six individual publications which are summarized in this report. Of these publications, four are published refereed journal articles, one is an accepted refereed journal article which has not yet been published, and one is a non-refereed software manual. The report concludes with a discussion of future research directions and exit plan.

  14. Final report on LDRD project: Simulation/optimization tools for system variability analysis

    Energy Technology Data Exchange (ETDEWEB)

    R. L. Bierbaum; R. F. Billau; J. E. Campbell; K. D. Marx; R. J. Sikorski; B. M. Thompson; S. D. Wix

    1999-10-01

    >This work was conducted during FY98 (Proposal Number 98-0036) and FY99 (Proposal Number 99-0818) under the auspices of the Sandia National Laboratories Laboratory-Directed Research and Development (LDRD) program. Electrical simulation typically treats a single data point in the very large input space of component properties. For electrical simulation to reach its full potential as a design tool, it must be able to address the unavoidable variability and uncertainty in component properties. Component viability is strongly related to the design margin (and reliability) of the end product. During the course of this project, both tools and methodologies were developed to enable analysis of variability in the context of electrical simulation tools. Two avenues to link relevant tools were also developed, and the resultant toolset was applied to a major component.

  15. Final Report for LDRD Project on Rapid Problem Setup for Mesh-Based Simulation (Rapsodi)

    Energy Technology Data Exchange (ETDEWEB)

    Brown, D L; Henshaw, W; Petersson, N A; Fast, P; Chand, K

    2003-02-07

    Under LLNL Exploratory Research LDRD funding, the Rapsodi project developed rapid setup technology for computational physics and engineering problems that require computational representations of complex geometry. Many simulation projects at LLNL involve the solution of partial differential equations in complex 3-D geometries. A significant bottleneck in carrying out these simulations arises in converting some specification of a geometry, such as a computer-aided design (CAD) drawing to a computationally appropriate 3-D mesh that can be used for simulation and analysis. Even using state-of-the-art mesh generation software, this problem setup step typically has required weeks or months, which is often much longer than required to carry out the computational simulation itself. The Rapsodi project built computational tools and designed algorithms that help to significantly reduce this setup time to less than a day for many realistic problems. The project targeted rapid setup technology for computational physics and engineering problems that use mixed-element unstructured meshes, overset meshes or Cartesian-embedded boundary (EB) meshes to represent complex geometry. It also built tools that aid in constructing computational representations of geometry for problems that do not require a mesh. While completely automatic mesh generation is extremely difficult, the amount of manual labor required can be significantly reduced. By developing novel, automated, component-based mesh construction procedures and automated CAD geometry repair and cleanup tools, Rapsodi has significantly reduced the amount of hand crafting required to generate geometry and meshes for scientific simulation codes.

  16. RF/microwave properties of nanotubes and nanowires : LDRD Project 105876 final report.

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    Scrymgeour, David; Lee, Mark; Hsu, Julia W. P.; Highstrete, Clark

    2009-09-01

    LDRD Project 105876 was a research project whose primary goal was to discover the currently unknown science underlying the basic linear and nonlinear electrodynamic response of nanotubes and nanowires in a manner that will support future efforts aimed at converting forefront nanoscience into innovative new high-frequency nanodevices. The project involved experimental and theoretical efforts to discover and understand high frequency (MHz through tens of GHz) electrodynamic response properties of nanomaterials, emphasizing nanowires of silicon, zinc oxide, and carbon nanotubes. While there is much research on DC electrical properties of nanowires, electrodynamic characteristics still represent a major new frontier in nanotechnology. We generated world-leading insight into how the low dimensionality of these nanomaterials yields sometimes desirable and sometimes problematic high-frequency properties that are outside standard model electron dynamics. In the cases of silicon nanowires and carbon nanotubes, evidence of strong disorder or glass-like charge dynamics was measured, indicating that these materials still suffer from serious inhomogeneities that limit there high frequency performance. Zinc oxide nanowires were found to obey conventional Drude dynamics. In all cases, a significant practical problem involving large impedance mismatch between the high intrinsic impedance of all nanowires and nanotubes and high-frequency test equipment had to be overcome.

  17. A configuration space toolkit for automated spatial reasoning: Technical results and LDRD project final report

    Energy Technology Data Exchange (ETDEWEB)

    Xavier, P.G.; LaFarge, R.A.

    1997-02-01

    A robot`s configuration space (c-space) is the space of its kinematic degrees of freedom, e.g., the joint-space of an arm. Sets in c-space can be defined that characterize a variety of spatial relationships, such as contact between the robot and its environment. C-space techniques have been fundamental to research progress in areas such as motion planning and physically-based reasoning. However, practical progress has been slowed by the difficulty of implementing the c-space abstraction inside each application. For this reason, we proposed a Configuration Space Toolkit of high-performance algorithms and data structures meeting these needs. Our intent was to develop this robotics software to provide enabling technology to emerging applications that apply the c-space abstraction, such as advanced motion planning, teleoperation supervision, mechanism functional analysis, and design tools. This final report presents the research results and technical achievements of this LDRD project. Key results and achievements included (1) a hybrid Common LISP/C prototype that implements the basic C-Space abstraction, (2) a new, generic, algorithm for constructing hierarchical geometric representations, and (3) a C++ implementation of an algorithm for fast distance computation, interference detection, and c-space point-classification. Since the project conclusion, motion planning researchers in Sandia`s Intelligent Systems and Robotics Center have been using the CSTk libcstk.so C++ library. The code continues to be used, supported, and improved by projects in the ISRC.

  18. Integrated computer control system CORBA-based simulator FY98 LDRD project final summary report

    International Nuclear Information System (INIS)

    The CORBA-based Simulator was a Laboratory Directed Research and Development (LDRD) project that applied simulation techniques to explore critical questions about distributed control architecture. The simulator project used a three-prong approach comprised of a study of object-oriented distribution tools, computer network modeling, and simulation of key control system scenarios. This summary report highlights the findings of the team and provides the architectural context of the study. For the last several years LLNL has been developing the Integrated Computer Control System (ICCS), which is an abstract object-oriented software framework for constructing distributed systems. The framework is capable of implementing large event-driven control systems for mission-critical facilities such as the National Ignition Facility (NIF). Tools developed in this project were applied to the NIF example architecture in order to gain experience with a complex system and derive immediate benefits from this LDRD. The ICCS integrates data acquisition and control hardware with a supervisory system, and reduces the amount of new coding and testing necessary by providing prebuilt components that can be reused and extended to accommodate specific additional requirements. The framework integrates control point hardware with a supervisory system by providing the services needed for distributed control such as database persistence, system start-up and configuration, graphical user interface, status monitoring, event logging, scripting language, alert management, and access control. The design is interoperable among computers of different kinds and provides plug-in software connections by leveraging a common object request brokering architecture (CORBA) to transparently distribute software objects across the network of computers. Because object broker distribution applied to control systems is relatively new and its inherent performance is roughly threefold less than traditional point

  19. A Case Study in Competitive Technical and Market Intelligence Support and Lessons Learned for the uChemLab LDRD Grand Challenge Project; TOPICAL

    International Nuclear Information System (INIS)

    The(mu)ChemLab(trademark) Laboratory Directed Research and Development (LDRD) Grand Challenge project began in October 1996 and ended in September 2000. The technical managers of the(mu)ChemLab(trademark) project and the LDRD office, with the support of a consultant, conducted a competitive technical and market demand intelligence analysis of the(mu)ChemLab(trademark). The managers used this knowledge to make project decisions and course adjustments. CTI/MDI positively impacted the project's technology development, uncovered potential technology partnerships, and supported eventual industry partner contacts. CTI/MDI analysis is now seen as due diligence and the(mu)ChemLab(trademark) project is now the model for other Sandia LDRD Grand Challenge undertakings. This document describes the CTI/MDI analysis and captures the more important ''lessons learned'' of this Grand Challenge project, as reported by the project's management team

  20. LDRD LW Project Final Report:Resolving the Earthquake Source Scaling Problem

    Energy Technology Data Exchange (ETDEWEB)

    Mayeda, K; Felker, S; Gok, R; O' Boyle, J; Walter, W R; Ruppert, S

    2004-02-10

    The scaling behavior of basic earthquake source parameters such as the energy release per unit area of fault slip, quantitatively measured as the apparent stress, is currently in dispute. There are compelling studies that show apparent stress is constant over a wide range of moments (e.g. Choy and Boatwright, 1995; McGarr, 1999; Ide and Beroza, 2001, Ide et al. 2003). Other equally compelling studies find the apparent stress increases with moment (e.g. Kanamori et al., 1993; Abercrombie, 1995; Mayeda and Walter, 1996; Izutani and Kanamori, 2001; Richardson and Jordan, 2002). The resolution of this issue is complicated by the difficulty of accurately accounting for attenuation, radiation inhomogeneities, bandwidth and determining the seismic energy radiated by earthquakes over a wide range of event sizes in a consistent manner. As one part of our LDRD project we convened a one-day workshop on July 24, 2003 in Livermore to review the current state of knowledge on this topic and discuss possible methods of resolution with many of the world's foremost experts.

  1. RF/Microwave properties and applications of directly assembled nanotubes and nanowires: LDRD project 102662 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, Theresa (The Pennyslvania State University, University Park, PA 16802); Vallett, Aaron (The Pennyslvania State University, University Park, PA 16802); Lee, Mark; Shaner, Eric Arthur; Jones, Frank E.; Talin, Albert Alec; Highstrete, Clark

    2006-11-01

    LDRD Project 102662 provided support to pursue experiments aimed at measuring the basic electrodynamic response and possible applications of carbon nanotubes and silicon nanowires at radiofrequency to microwave frequencies, approximately 0.01 to 50 GHz. Under this project, a method was developed to integrate these nanomaterials onto high-frequency compatible co-planar waveguides. The complex reflection and transmission coefficients of the nanomaterials was studied as a function of frequency. From these data, the high-frequency loss characteristics of the nanomaterials were deduced. These data are useful to predict frequency dependence and power dissipation characteristics in new rf/microwave devices incorporating new nanomaterials.

  2. Final Report for LDRD Project 02-FS-009 Gigapixel Surveillance Camera

    Energy Technology Data Exchange (ETDEWEB)

    Marrs, R E; Bennett, C L

    2010-04-20

    The threats of terrorism and proliferation of weapons of mass destruction add urgency to the development of new techniques for surveillance and intelligence collection. For example, the United States faces a serious and growing threat from adversaries who locate key facilities underground, hide them within other facilities, or otherwise conceal their location and function. Reconnaissance photographs are one of the most important tools for uncovering the capabilities of adversaries. However, current imaging technology provides only infrequent static images of a large area, or occasional video of a small area. We are attempting to add a new dimension to reconnaissance by introducing a capability for large area video surveillance. This capability would enable tracking of all vehicle movements within a very large area. The goal of our project is the development of a gigapixel video surveillance camera for high altitude aircraft or balloon platforms. From very high altitude platforms (20-40 km altitude) it would be possible to track every moving vehicle within an area of roughly 100 km x 100 km, about the size of the San Francisco Bay region, with a gigapixel camera. Reliable tracking of vehicles requires a ground sampling distance (GSD) of 0.5 to 1 m and a framing rate of approximately two frames per second (fps). For a 100 km x 100 km area the corresponding pixel count is 10 gigapixels for a 1-m GSD and 40 gigapixels for a 0.5-m GSD. This is an order of magnitude beyond the 1 gigapixel camera envisioned in our LDRD proposal. We have determined that an instrument of this capacity is feasible.

  3. Development of a cryogenic EOS capability for the Z Pulsed Radiation Source: Goals and accomplishments of FY97 LDRD project

    International Nuclear Information System (INIS)

    Experimental cryogenic capabilities are essential for the study of ICF high-gain target and weapons effects issues involving dynamic materials response at low temperatures. This report describes progress during the period 2/97-11/97 on the FY97 LDRD project ''Cryogenic EOS Capabilities on Pulsed Radiation Sources (Z Pinch)''. The goal of this project is the development of a general purpose cryogenic target system for precision EOS and shock physics measurements at liquid helium temperatures on the Z accelerator Z-pinch pulsed radiation source. Activity during the FY97 LDRD phase of this project has focused on development of a conceptual design for the cryogenic target system based on consideration of physics, operational, and safety issues, design and fabrication of principal system components, construction and instrumentation of a cryogenic test facility for off-line thermal and optical testing at liquid helium temperatures, initial thermal testing of a cryogenic target assembly, and the design of a cryogenic system interface to the Z pulsed radiation source facility. The authors discuss these accomplishments as well as elements of the project that require further work

  4. Electron paramagnetic resonance (EPR) biodosimetry

    International Nuclear Information System (INIS)

    Radiation-induced electron paramagnetic resonance (EPR) signals were first reported by Gordy et al. [Proc. Natl. Acad. Sci. USA 41 (1955) 983]. The application of EPR spectroscopy to ionizing radiation dosimetry was later proposed by Brady et al. [Health Phys. 15 (1968) 43]. Since that time EPR dosimetry has been applied to accident and epidemiologic dose reconstruction, radiation therapy, food irradiation, quality assurance programs and archaeological dating. Materials that have been studied include bone, tooth enamel, alanine and quartz. This review paper presents the fundamentals and applications of EPR biodosimetry. Detailed information regarding sample collection and preparation, EPR measurements, dose reconstruction, and data analysis and interpretation will be reviewed for tooth enamel. Examples of EPR biodosimetry application in accidental overexposures, radiopharmaceutical dose assessment and retrospective epidemiologic studies will also be presented

  5. Final report on LDRD project : coupling strategies for multi-physics applications.

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, Matthew Morgan; Moffat, Harry K.; Carnes, Brian; Hooper, Russell Warren; Pawlowski, Roger P.

    2007-11-01

    Many current and future modeling applications at Sandia including ASC milestones will critically depend on the simultaneous solution of vastly different physical phenomena. Issues due to code coupling are often not addressed, understood, or even recognized. The objectives of the LDRD has been both in theory and in code development. We will show that we have provided a fundamental analysis of coupling, i.e., when strong coupling vs. a successive substitution strategy is needed. We have enabled the implementation of tighter coupling strategies through additions to the NOX and Sierra code suites to make coupling strategies available now. We have leveraged existing functionality to do this. Specifically, we have built into NOX the capability to handle fully coupled simulations from multiple codes, and we have also built into NOX the capability to handle Jacobi Free Newton Krylov simulations that link multiple applications. We show how this capability may be accessed from within the Sierra Framework as well as from outside of Sierra. The critical impact from this LDRD is that we have shown how and have delivered strategies for enabling strong Newton-based coupling while respecting the modularity of existing codes. This will facilitate the use of these codes in a coupled manner to solve multi-physic applications.

  6. LDRD Annual Report FY2006

    Energy Technology Data Exchange (ETDEWEB)

    Sketchley, J A; Kotta, P; De Yoreo, J; Jackson, K; van Bibber, K

    2007-03-20

    The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Laboratory Science and Technology Office, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration in national security, energy security, environmental management, bioscience and technology to improve human health, and breakthroughs in fundamental science and technology. The accomplishments described in this Annual Report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $92 million for FY2006 sponsored 188 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the

  7. LDRD Annual Report FY2006

    International Nuclear Information System (INIS)

    The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Laboratory Science and Technology Office, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration in national security, energy security, environmental management, bioscience and technology to improve human health, and breakthroughs in fundamental science and technology. The accomplishments described in this Annual Report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $92 million for FY2006 sponsored 188 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest

  8. Final report on LDRD Project: Quantum confinement and light emission in silicon nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Guilinger, T.R.; Kelly, M.J.; Follstaedt, D.M. [and others

    1995-02-01

    Electrochemically formed porous silicon (PS) was reported in 1991 to exhibit visible photoluminescence. This discovery could lead to the use of integrated silicon-based optoelectronic devices. This LDRD addressed two general goals for optical emission from Si: (1) investigate the mechanisms responsible for light emission, and (2) tailor the microstructure and composition of the Si to obtain photoemission suitable for working devices. PS formation, composition, morphology, and microstructure have been under investigation at Sandia for the past ten years for applications in silicon-on-insulator microelectronics, micromachining, and chemical sensors. The authors used this expertise to form luminescent PS at a variety of wavelengths and have used analytical techniques such as in situ Raman and X-ray reflectivity to investigate the luminescence mechanism and quantify the properties of the porous silicon layer. Further, their experience with ion implantation in Si lead to an investigation into alternate methods of producing Si nanostructures that visibly luminesce.

  9. Final report for LDRD project 11-0783 : directed robots for increased military manpower effectiveness.

    Energy Technology Data Exchange (ETDEWEB)

    Rohrer, Brandon Robinson; Rothganger, Fredrick H.; Wagner, John S.; Xavier, Patrick Gordon; Morrow, James Dan

    2011-09-01

    The purpose of this LDRD is to develop technology allowing warfighters to provide high-level commands to their unmanned assets, freeing them to command a group of them or commit the bulk of their attention elsewhere. To this end, a brain-emulating cognition and control architecture (BECCA) was developed, incorporating novel and uniquely capable feature creation and reinforcement learning algorithms. BECCA was demonstrated on both a mobile manipulator platform and on a seven degree of freedom serial link robot arm. Existing military ground robots are almost universally teleoperated and occupy the complete attention of an operator. They may remove a soldier from harm's way, but they do not necessarily reduce manpower requirements. Current research efforts to solve the problem of autonomous operation in an unstructured, dynamic environment fall short of the desired performance. In order to increase the effectiveness of unmanned vehicle (UV) operators, we proposed to develop robots that can be 'directed' rather than remote-controlled. They are instructed and trained by human operators, rather than driven. The technical approach is modeled closely on psychological and neuroscientific models of human learning. Two Sandia-developed models are utilized in this effort: the Sandia Cognitive Framework (SCF), a cognitive psychology-based model of human processes, and BECCA, a psychophysical-based model of learning, motor control, and conceptualization. Together, these models span the functional space from perceptuo-motor abilities, to high-level motivational and attentional processes.

  10. LDRD project final report : hybrid AI/cognitive tactical behavior framework for LVC.

    Energy Technology Data Exchange (ETDEWEB)

    Djordjevich, Donna D.; Xavier, Patrick Gordon; Brannon, Nathan Gregory; Hart, Brian E.; Hart, Derek H.; Little, Charles Quentin; Oppel, Fred John III; Linebarger, John Michael; Parker, Eric Paul

    2012-01-01

    This Lab-Directed Research and Development (LDRD) sought to develop technology that enhances scenario construction speed, entity behavior robustness, and scalability in Live-Virtual-Constructive (LVC) simulation. We investigated issues in both simulation architecture and behavior modeling. We developed path-planning technology that improves the ability to express intent in the planning task while still permitting an efficient search algorithm. An LVC simulation demonstrated how this enables 'one-click' layout of squad tactical paths, as well as dynamic re-planning for simulated squads and for real and simulated mobile robots. We identified human response latencies that can be exploited in parallel/distributed architectures. We did an experimental study to determine where parallelization would be productive in Umbra-based force-on-force (FOF) simulations. We developed and implemented a data-driven simulation composition approach that solves entity class hierarchy issues and supports assurance of simulation fairness. Finally, we proposed a flexible framework to enable integration of multiple behavior modeling components that model working memory phenomena with different degrees of sophistication.

  11. LDRD FY 2014 Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Anita Gianotto; Dena Tomchak

    2013-08-01

    As required by DOE Order 413.2B the FY 2014 Program Plan is written to communicate ares of investment and approximate amounts being requested for the upcoming fiscal year. The program plan also includes brief highlights of current or previous LDRD projects that have an opportunity to impact our Nation's current and future energy challenges.

  12. LDRD Final Report - Investigations of the impact of the process integration of deposited magnetic films for magnetic memory technologies on radiation hardened CMOS devices and circuits - LDRD Project (FY99)

    International Nuclear Information System (INIS)

    This project represented a coordinated LLNL-SNL collaboration to investigate the feasibility of developing radiation-hardened magnetic non-volatile memories using giant magnetoresistance (GMR) materials. The intent of this limited-duration study was to investigate whether giant magnetoresistance (GMR) materials similar to those used for magnetic tunnel junctions (MTJs) were process compatible with functioning CMOS circuits. Sandia's work on this project demonstrated that deposition of GMR materials did not affect the operation nor the radiation hardness of Sandia's rad-hard CMOS technology, nor did the integration of GMR materials and exposure to ionizing radiation affect the magnetic properties of the GMR films. Thus, following deposition of GMR films on rad-hard integrated circuits, both the circuits and the films survived ionizing radiation levels consistent with DOE mission requirements. Furthermore, Sandia developed techniques to pattern deposited GMR films without degrading the completed integrated circuits upon which they were deposited. The present feasibility study demonstrated all the necessary processing elements to allow fabrication of the non-volatile memory elements onto an existing CMOS chip, and even allow the use of embedded (on-chip) non-volatile memories for system-on-a-chip applications, even in demanding radiation environments. However, funding agencies DTRA, AIM, and DARPA did not have any funds available to support the required follow-on technology development projects that would have been required to develop functioning prototype circuits, nor were such funds available from LDRD nor from other DOE program funds

  13. An automated imaging system for radiation biodosimetry.

    Science.gov (United States)

    Garty, Guy; Bigelow, Alan W; Repin, Mikhail; Turner, Helen C; Bian, Dakai; Balajee, Adayabalam S; Lyulko, Oleksandra V; Taveras, Maria; Yao, Y Lawrence; Brenner, David J

    2015-07-01

    We describe here an automated imaging system developed at the Center for High Throughput Minimally Invasive Radiation Biodosimetry. The imaging system is built around a fast, sensitive sCMOS camera and rapid switchable LED light source. It features complete automation of all the steps of the imaging process and contains built-in feedback loops to ensure proper operation. The imaging system is intended as a back end to the RABiT-a robotic platform for radiation biodosimetry. It is intended to automate image acquisition and analysis for four biodosimetry assays for which we have developed automated protocols: The Cytokinesis Blocked Micronucleus assay, the γ-H2AX assay, the Dicentric assay (using PNA or FISH probes) and the RABiT-BAND assay. PMID:25939519

  14. Dynamic compression of synthetic diamond windows (final report for LDRD project 93531).

    Energy Technology Data Exchange (ETDEWEB)

    Dolan, Daniel H.,

    2008-09-01

    Diamond is an attractive dynamic compression window for many reasons: high elastic limit,large mechanical impedance, and broad transparency range. Natural diamonds, however, aretoo expensive to be used in destructive experiments. Chemical vapor deposition techniquesare now able to produce large single-crystal windows, opening up many potential dynamiccompression applications. This project studied the behavior of synthetic diamond undershock wave compression. The results suggest that synthetic diamond could be a usefulwindow in this field, though complete characterization proved elusive.3

  15. Characterizing the emissivity of materials under dynamic compression (final report for LDRD project 79877)

    International Nuclear Information System (INIS)

    Temperature measurements are crucial to equation of state development, but difficult to perform reliably. In the case of infrared pyrometry, a large uncertainty comes from the fact that sample emissivity (the deviation from a blackbody) is unknown. In this project, a method for characterizing the emissivity of shocked materials was developed. By coupling infrared radiation from the National Synchrotron Light Source to a gas gun system, broad spectrum emissivity changes were studied to a peak stress of 8 GPa. Emissivity measurements were performed on standard metals (Al, Cr, Cu, and Pt) as well as a high emissivity coating developed at Sandia

  16. Final report on LDRD project : single-photon-sensitive imaging detector arrays at 1600 nm.

    Energy Technology Data Exchange (ETDEWEB)

    Childs, Kenton David; Serkland, Darwin Keith; Geib, Kent Martin; Hawkins, Samuel D.; Carroll, Malcolm S.; Klem, John Frederick; Sheng, Josephine Juin-Jye; Patel, Rupal K.; Bolles, Desta; Bauer, Tom M.; Koudelka, Robert

    2006-11-01

    The key need that this project has addressed is a short-wave infrared light detector for ranging (LIDAR) imaging at temperatures greater than 100K, as desired by nonproliferation and work for other customers. Several novel device structures to improve avalanche photodiodes (APDs) were fabricated to achieve the desired APD performance. A primary challenge to achieving high sensitivity APDs at 1550 nm is that the small band-gap materials (e.g., InGaAs or Ge) necessary to detect low-energy photons exhibit higher dark counts and higher multiplication noise compared to materials like silicon. To overcome these historical problems APDs were designed and fabricated using separate absorption and multiplication (SAM) regions. The absorption regions used (InGaAs or Ge) to leverage these materials 1550 nm sensitivity. Geiger mode detection was chosen to circumvent gain noise issues in the III-V and Ge multiplication regions, while a novel Ge/Si device was built to examine the utility of transferring photoelectrons in a silicon multiplication region. Silicon is known to have very good analog and GM multiplication properties. The proposed devices represented a high-risk for high-reward approach. Therefore one primary goal of this work was to experimentally resolve uncertainty about the novel APD structures. This work specifically examined three different designs. An InGaAs/InAlAs Geiger mode (GM) structure was proposed for the superior multiplication properties of the InAlAs. The hypothesis to be tested in this structure was whether InAlAs really presented an advantage in GM. A Ge/Si SAM was proposed representing the best possible multiplication material (i.e., silicon), however, significant uncertainty existed about both the Ge material quality and the ability to transfer photoelectrons across the Ge/Si interface. Finally a third pure germanium GM structure was proposed because bulk germanium has been reported to have better dark count properties. However, significant

  17. FY2014 LBNL LDRD Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Ho, Darren [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-06-01

    Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE’s National Laboratory System, Berkeley Lab supports DOE’s missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation. The LDRD program supports Berkeley Lab’s mission in many ways. First, because LDRD funds can be allocated within a relatively short time frame, Berkeley Lab researchers can support the mission of the Department of Energy (DOE) and serve the needs of the nation by quickly responding to forefront scientific problems. Second, LDRD enables Berkeley Lab to attract and retain highly qualified scientists and to support their efforts to carry out worldleading research. In addition, the LDRD program also supports new projects that involve graduate students and postdoctoral fellows, thus contributing to the education mission of Berkeley Lab.

  18. Final LDRD report :

    Energy Technology Data Exchange (ETDEWEB)

    Clark, Blythe G.; Rajasekhara, Shreyas; Enos, David George; Dingreville, Remi Philippe Michel; Doyle, Barney Lee; Hattar, Khalid Mikhiel; Weiner, Ruth F.

    2013-09-01

    We present the results of a three-year LDRD project focused on understanding microstructural evolution and related property changes in Zr-based nuclear cladding materials towards the development of high fidelity predictive simulations for long term dry storage. Experiments and modeling efforts have focused on the effects of hydride formation and accumulation of irradiation defects. Key results include: determination of the influence of composition and defect structures on hydride formation; measurement of the electrochemical property differences between hydride and parent material for understanding and predicting corrosion resistance; in situ environmental transmission electron microscope observation of hydride formation; development of a predictive simulation for mechanical property changes as a function of irradiation dose; novel test method development for microtensile testing of ionirradiated material to simulate the effect of neutron irradiation on mechanical properties; and successful demonstration of an Idaho National Labs-based sample preparation and shipping method for subsequent Sandia-based analysis of post-reactor cladding.

  19. LDRD Final Report - Investigations of the impact of the process integration of deposited magnetic films for magnetic memory technologies on radiation-hardened CMOS devices and circuits - LDRD Project (FY99)

    Energy Technology Data Exchange (ETDEWEB)

    MYERS,DAVID R.; JESSING,JEFFREY R.; SPAHN,OLGA B.; SHANEYFELT,MARTY R.

    2000-01-01

    This project represented a coordinated LLNL-SNL collaboration to investigate the feasibility of developing radiation-hardened magnetic non-volatile memories using giant magnetoresistance (GMR) materials. The intent of this limited-duration study was to investigate whether giant magnetoresistance (GMR) materials similar to those used for magnetic tunnel junctions (MTJs) were process compatible with functioning CMOS circuits. Sandia's work on this project demonstrated that deposition of GMR materials did not affect the operation nor the radiation hardness of Sandia's rad-hard CMOS technology, nor did the integration of GMR materials and exposure to ionizing radiation affect the magnetic properties of the GMR films. Thus, following deposition of GMR films on rad-hard integrated circuits, both the circuits and the films survived ionizing radiation levels consistent with DOE mission requirements. Furthermore, Sandia developed techniques to pattern deposited GMR films without degrading the completed integrated circuits upon which they were deposited. The present feasibility study demonstrated all the necessary processing elements to allow fabrication of the non-volatile memory elements onto an existing CMOS chip, and even allow the use of embedded (on-chip) non-volatile memories for system-on-a-chip applications, even in demanding radiation environments. However, funding agencies DTRA, AIM, and DARPA did not have any funds available to support the required follow-on technology development projects that would have been required to develop functioning prototype circuits, nor were such funds available from LDRD nor from other DOE program funds.

  20. 1999 LDRD Laboratory Directed Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Rita Spencer; Kyle Wheeler

    2000-06-01

    This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  1. Final report for LDRD project {open_quotes}A new approach to protein function and structure prediction{close_quotes}

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, C.A.

    1997-03-01

    This report describes the research performed under the laboratory-Directed Research and Development (LDRD) grant {open_quotes}A new approach to protein function and structure prediction{close_quotes}, funded FY94-6. We describe the goals of the research, motivate and list our improvements to the state of the art in multiple sequence alignment and phylogeny (evolutionary tree) construction, but leave technical details to the six publications resulting from this work. At least three algorithms for phylogeny construction or tree consensus have been implemented and used by researchers outside of Sandia.

  2. Tiger LDRD final report

    Energy Technology Data Exchange (ETDEWEB)

    Steich, D J; Brugger, S T; Kallman, J S; White, D A

    2000-02-01

    This final report describes our efforts on the Three-Dimensional Massively Parallel CEM Technologies LDRD project (97-ERD-009). Significant need exists for more advanced time domain computational electromagnetics modeling. Bookkeeping details and modifying inflexible software constitute a vast majority of the effort required to address such needs. The required effort escalates rapidly as problem complexity increases. For example, hybrid meshes requiring hybrid numerics on massively parallel platforms (MPPs). This project attempts to alleviate the above limitations by investigating flexible abstractions for these numerical algorithms on MPPs using object-oriented methods, providing a programming environment insulating physics from bookkeeping. The three major design iterations during the project, known as TIGER-I to TIGER-III, are discussed. Each version of TIGER is briefly discussed along with lessons learned during the development and implementation. An Application Programming Interface (API) of the object-oriented interface for Tiger-III is included in three appendices. The three appendices contain the Utilities, Entity-Attribute, and Mesh libraries developed during the project. The API libraries represent a snapshot of our latest attempt at insulated the physics from the bookkeeping.

  3. Hardness Assurance for Low-Energy Proton-Induced Single-Event Effects: Final report for LDRD Project 173134

    Energy Technology Data Exchange (ETDEWEB)

    Dodds, Nathaniel Anson [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    This report briefly summarizes three publications that resulted from a two-year LDRD. The three publications address a recently emerging reliability issue: namely, that low-energy protons (LEPs) can cause single-event effects (SEEs) in highly scaled microelectronics. These publications span from low to high technology readiness levels. In the first, novel experiments were used to prove that proton direct ionization is the dominant mechanism for LEP-induced SEEs. In the second, a simple method was developed to calculate expected on-orbit error rates for LEP effects. This simplification was enabled by creating (and characterizing) an accelerated space-like LEP environment in the laboratory. In the third publication, this new method was applied to many memory circuits from the 20-90 nm technology nodes to study the general importance of LEP effects, in terms of their contribution to the total on-orbit SEE rate.

  4. Microwave to millimeter-wave electrodynamic response and applications of semiconductor nanostructures: LDRD project 67025 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Shaner, Eric Arthur; Lee, Mark; Averitt, R. D. (Los Alamos National Laboratory); Highstrete, Clark; Taylor, A. J. (Los Alamos National Laboratory); Padilla, W. J. (Los Alamos National Laboratory); Reno, John Louis; Wanke, Michael Clement; Allen, S. James (University of California Santa Barbara)

    2006-11-01

    Solid-state lighting (SSL) technologies, based on semiconductor light emitting devices, have the potential to reduce worldwide electricity consumption by more than 10%, which could significantly reduce U.S. dependence on imported energy and improve energy security. The III-nitride (AlGaInN) materials system forms the foundation for white SSL and could cover a wide spectral range from the deep UV to the infrared. For this LDRD program, we have investigated the synthesis of single-crystalline III-nitride nanowires and heterostructure nanowires, which may possess unique optoelectronic properties. These novel structures could ultimately lead to the development of novel and highly efficient SSL nanodevice applications. GaN and III-nitride core-shell heterostructure nanowires were successfully synthesized by metal organic chemical vapor deposition (MOCVD) on two-inch wafer substrates. The effect of process conditions on nanowire growth was investigated, and characterization of the structural, optical, and electrical properties of the nanowires was also performed.

  5. 2007 LDRD ANNUAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    French, T

    2008-12-16

    I am pleased to present the fiscal year 2007 Laboratory Directed Research and Development (LDRD) annual report. This represents the first year that SRNL has been eligible for LDRD participation and our results to date demonstrate we are off to an excellent start. SRNL became a National Laboratory in 2004, and was designated the 'Corporate Laboratory' for the DOE Office of Environmental Management (EM) in 2006. As you will see, we have made great progress since these designations. The LDRD program is one of the tools SRNL is using to enable achievement of our strategic goals for the DOE. The LDRD program allows the laboratory to blend a strong basic science component into our applied technical portfolio. This blending of science with applied technology provides opportunities for our scientists to strengthen our capabilities and delivery. The LDRD program is vital to help SRNL attract and retain leading scientists and engineers who will help build SRNL's future and achieve DOE mission objectives. This program has stimulated our research staff creativity, while realizing benefits from their participation. This investment will yield long term dividends to the DOE in its Environmental Management, Energy, and National Security missions.

  6. Final report for LDRD project 11-0029 : high-interest event detection in large-scale multi-modal data sets : proof of concept.

    Energy Technology Data Exchange (ETDEWEB)

    Rohrer, Brandon Robinson

    2011-09-01

    Events of interest to data analysts are sometimes difficult to characterize in detail. Rather, they consist of anomalies, events that are unpredicted, unusual, or otherwise incongruent. The purpose of this LDRD was to test the hypothesis that a biologically-inspired anomaly detection algorithm could be used to detect contextual, multi-modal anomalies. There currently is no other solution to this problem, but the existence of a solution would have a great national security impact. The technical focus of this research was the application of a brain-emulating cognition and control architecture (BECCA) to the problem of anomaly detection. One aspect of BECCA in particular was discovered to be critical to improved anomaly detection capabilities: it's feature creator. During the course of this project the feature creator was developed and tested against multiple data types. Development direction was drawn from psychological and neurophysiological measurements. Major technical achievements include the creation of hierarchical feature sets created from both audio and imagery data.

  7. 2013 SRNL LDRD Annual Report

    International Nuclear Information System (INIS)

    This report demonstrates the execution of our LDRD program within the objectives and guidelines outlined by the Department of Energy (DOE) through the DOE Order 413.2b. The projects described within the report align purposefully with SRNL's strategic vision and provide great value to the DOE. The diversity exhibited in the research and development projects underscores the DOE Office of Environmental Management (DOE-EM) mission and enhances that mission by developing the technical capabilities and human capital necessary to support future DOE-EM national needs. As a multiprogram national laboratory, SRNL is applying those capabilities to achieve tangible results for the nation in National Security, Environmental Stewardship, Clean Energy and Nuclear Materials Management

  8. 2013 SRNL LDRD Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    McWhorter, S.

    2014-03-07

    This report demonstrates the execution of our LDRD program within the objectives and guidelines outlined by the Department of Energy (DOE) through the DOE Order 413.2b. The projects described within the report align purposefully with SRNL’s strategic vision and provide great value to the DOE. The diversity exhibited in the research and development projects underscores the DOE Office of Environmental Management (DOE-EM) mission and enhances that mission by developing the technical capabilities and human capital necessary to support future DOE-EM national needs. As a multiprogram national laboratory, SRNL is applying those capabilities to achieve tangible results for the nation in National Security, Environmental Stewardship, Clean Energy and Nuclear Materials Management.

  9. Realising the European network of biodosimetry: RENEB-status quo

    International Nuclear Information System (INIS)

    Creating a sustainable network in biological and retrospective dosimetry that involves a large number of experienced laboratories throughout the European Union (EU) will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well-organised cooperative action involving EU laboratories will offer the best chance for fast and trustworthy dose assessments that are urgently needed in an emergency situation. To this end, the EC supports the establishment of a European network in biological dosimetry (RENEB). The RENEB project started in January 2012 involving cooperation of 23 organisations from 16 European countries. The purpose of RENEB is to increase the biodosimetry capacities in case of large-scale radiological emergency scenarios. The progress of the project since its inception is presented, comprising the consolidation process of the network with its operational platform, intercomparison exercises, training activities, proceedings in quality assurance and horizon scanning for new methods and partners. Additionally, the benefit of the network for the radiation research community as a whole is addressed. (authors)

  10. Method for efficient establishment of technical biodosimetry competence

    International Nuclear Information System (INIS)

    The current gold standard in biodosimetry, the dicentric assay, requires documented technical competence. Expertise is developed over time by evaluation of thousands of metaphases. Competence is documented through establishment of a dose-response curve, required by any service laboratory performing biodosimetry. Consistent and reliable evaluations must be established for new observers that might contribute to analyses for biological dose assessments. Discrepancies in evaluations jeopardize the reliability of assessments. The Swedish Defence Research Agency (FOI) together with the Norwegian Radiation Protection Authority (NRPA) conducted an inter-calibration exercise for the purpose of establishing comparable scoring criteria for evaluation of aberrations in metaphases. The exercise revealed specific aberrations that were difficult to identify and were consistent sources of uncertainty. Subsequently, a report detailing the FOI's scoring criteria was developed with visual examples and a strategy for establishing technical competence in metaphase scoring in an efficient manner evolved. Key components of the strategy are the review of guidance for biodosimetry, performance of inter-calibration exercises with previously established data sets, review of incongruous evaluations with a well-established observer, follow-up exercises depending on the initial outcome, and inter-comparisons to document agreement. Methods suggested here could be applied in training of new personnel. Documentation of methods in other laboratories could facilitate more consistent scoring criteria among the biodosimetry community, a problem observed in previous international inter-comparisons. Improved consistency among biodosimetry laboratories could facilitate reliably sharing the work load among different members of the biodosimetry community in the event of a mass casualty accident

  11. Final report on grand challenge LDRD project : a revolution in lighting : building the science and technology base for ultra-efficient solid-state lighting.

    Energy Technology Data Exchange (ETDEWEB)

    Copeland, Robert Guild; Mitchell, Christine Charlotte; Follstaedt, David Martin; Lee, Stephen Roger; Shul, Randy John; Fischer, Arthur Joseph; Chow, Weng Wah Dr.; Myers, Samuel Maxwell, Jr.; Thoma, Steven George; Gee, James Martin; Coltrin, Michael Elliott; Burdick, Brent A.; Salamone, Angelo, L., Jr.; Hadley, G. Ronald; Elliott, Russell D.; Campbell, Jonathan M.; Abrams, Billie Lynn; Wendt, Joel Robert; Pawlowski, Roger Patrick; Simpson, Regina Lynn; Kurtz, Steven Ross; Cole, Phillip James; Fullmer, Kristine Wanta; Seager, Carleton Hoover; Bogart, Katherine Huderle Andersen; Biefeld, Robert Malcolm; Kerley, Thomas M.; Norman, Adam K.; Tallant, David Robert; Woessner, Stephen Matthew; Figiel, Jeffrey James; Moffat, Harry K.; Provencio, Paula Polyak; Emerson, John Allen; Kaplar, Robert James; Wilcoxon, Jess Patrick; Waldrip, Karen Elizabeth; Rohwer, Lauren Elizabeth Shea; Cross, Karen Charlene; Wright, Alan Francis; Gonzales, Rene Marie; Salinger, Andrew Gerhard; Crawford, Mary Hagerott; Garcia, Marie L.; Allen, Mark S.; Southwell, Edwin T. (Perspectives, Sedona, AZ); Bauer, Tom M.; Monson, Mary Ann; Tsao, Jeffrey Yeenien; Creighton, James Randall; Allerman, Andrew Alan; Simmons, Jerry A.; Boyack, Kevin W.; Jones, Eric Daniel; Moran, Michael P.; Pinzon, Marcia J. (Perspectives, Sedona, AZ); Pinson, Ariane O. (Perspectives, Sedona, AZ); Miksovic, Ann E. (Perspectives, Sedona, AZ); Wang, George T.; Ashby, Carol Iris Hill; Missert, Nancy A.; Koleske, Daniel David; Rahal, Nabeel M.

    2004-06-01

    This SAND report is the final report on Sandia's Grand Challenge LDRD Project 27328, 'A Revolution in Lighting -- Building the Science and Technology Base for Ultra-Efficient Solid-state Lighting.' This project, which for brevity we refer to as the SSL GCLDRD, is considered one of Sandia's most successful GCLDRDs. As a result, this report reviews not only technical highlights, but also the genesis of the idea for Solid-state Lighting (SSL), the initiation of the SSL GCLDRD, and the goals, scope, success metrics, and evolution of the SSL GCLDRD over the course of its life. One way in which the SSL GCLDRD was different from other GCLDRDs was that it coincided with a larger effort by the SSL community - primarily industrial companies investing in SSL, but also universities, trade organizations, and other Department of Energy (DOE) national laboratories - to support a national initiative in SSL R&D. Sandia was a major player in publicizing the tremendous energy savings potential of SSL, and in helping to develop, unify and support community consensus for such an initiative. Hence, our activities in this area, discussed in Chapter 6, were substantial: white papers; SSL technology workshops and roadmaps; support for the Optoelectronics Industry Development Association (OIDA), DOE and Senator Bingaman's office; extensive public relations and media activities; and a worldwide SSL community website. Many science and technology advances and breakthroughs were also enabled under this GCLDRD, resulting in: 55 publications; 124 presentations; 10 book chapters and reports; 5 U.S. patent applications including 1 already issued; and 14 patent disclosures not yet applied for. Twenty-six invited talks were given, at prestigious venues such as the American Physical Society Meeting, the Materials Research Society Meeting, the AVS International Symposium, and the Electrochemical Society Meeting. This report contains a summary of these science and technology

  12. FY02 Engineering Technology Reports Volume 2: LDRD

    Energy Technology Data Exchange (ETDEWEB)

    Minichino, C; Meeker, D

    2003-05-19

    This report summarizes the science and technology research and development efforts in Lawrence Livermore National Laboratory's Engineering Directorate for FY2002, and exemplifies Engineering's 50-year history of developing the technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence and has prepared for this role with a skilled workforce and the technical resources developed through venues like the Laboratory Directed Research and Development Program (LDRD). This accomplishment is well summarized by Engineering's mission: ''To make programs succeed today and to ensure the vitality of the Laboratory tomorrow.'' Engineering's investment in new technologies is carried out through two programs, the ''Tech Base'' program (Volume I) and the LDRD program (Volume II). This report summarizes the LDRD portion of Engineering's Technology Program. LDRD is the vehicle for researching and developing those technologies and competencies that are cutting edge, or that require a significant level of research, or contain some unknown that needs to be fully understood. Tech Base is used to apply those technologies, or adapt them to a Laboratory need. The term commonly used for Tech Base projects is ''reduction to practice.'' Therefore, the LDRD report covered here has a strong research emphasis. Areas that are presented all fall into those needed to accomplish our mission. For FY2002, Engineering's LDRD projects were focused on mesoscale target fabrication and characterization, development of engineering computational capability, material studies and modeling, remote sensing and communications, and microtechnology for national security applications.

  13. Computational Biology: A Strategic Initiative LDRD

    Energy Technology Data Exchange (ETDEWEB)

    Barksy, D; Colvin, M

    2002-02-07

    The goal of this Strategic Initiative LDRD project was to establish at LLNL a new core capability in computational biology, combining laboratory strengths in high performance computing, molecular biology, and computational chemistry and physics. As described in this report, this project has been very successful in achieving this goal. This success is demonstrated by the large number of referred publications, invited talks, and follow-on research grants that have resulted from this project. Additionally, this project has helped build connections to internal and external collaborators and funding agencies that will be critical to the long-term vitality of LLNL programs in computational biology. Most importantly, this project has helped establish on-going research groups in the Biology and Biotechnology Research Program, the Physics and Applied Technology Directorate, and the Computation Directorate. These groups include three laboratory staff members originally hired as post-doctoral researchers for this strategic initiative.

  14. SRNL LDRD ANNUAL REPORT 2008

    Energy Technology Data Exchange (ETDEWEB)

    French, T

    2008-12-29

    The Laboratory Director is pleased to have the opportunity to present the 2008 Laboratory Directed Research and Development (LDRD) annual report. This is my first opportunity to do so, and only the second such report that has been issued. As will be obvious, SRNL has built upon the excellent start that was made with the LDRD program last year, and researchers have broken new ground in some important areas. In reviewing the output of this program this year, it is clear that the researchers implemented their ideas with creativity, skill and enthusiasm. It is gratifying to see this level of participation, because the LDRD program remains a key part of meeting SRNL's and DOE's strategic goals, and helps lay a solid scientific foundation for SRNL as the premier applied science laboratory. I also believe that the LDRD program's results this year have demonstrated SRNL's value as the EM Corporate Laboratory, having advanced knowledge in a spectrum of areas, including reduction of the technical risks of cleanup, separations science, packaging and transportation of nuclear materials, and many others. The research in support of Energy Security and National and Homeland Security has been no less notable. SRNL' s researchers have shown again that the nascent LDRD program is a sound investment for DOE that will pay off handsomely for the nation as time goes on.

  15. LDRD 149045 final report distinguishing documents.

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Scott A.

    2010-09-01

    This LDRD 149045 final report describes work that Sandians Scott A. Mitchell, Randall Laviolette, Shawn Martin, Warren Davis, Cindy Philips and Danny Dunlavy performed in 2010. Prof. Afra Zomorodian provided insight. This was a small late-start LDRD. Several other ongoing efforts were leveraged, including the Networks Grand Challenge LDRD, and the Computational Topology CSRF project, and the some of the leveraged work is described here. We proposed a sentence mining technique that exploited both the distribution and the order of parts-of-speech (POS) in sentences in English language documents. The ultimate goal was to be able to discover 'call-to-action' framing documents hidden within a corpus of mostly expository documents, even if the documents were all on the same topic and used the same vocabulary. Using POS was novel. We also took a novel approach to analyzing POS. We used the hypothesis that English follows a dynamical system and the POS are trajectories from one state to another. We analyzed the sequences of POS using support vector machines and the cycles of POS using computational homology. We discovered that the POS were a very weak signal and did not support our hypothesis well. Our original goal appeared to be unobtainable with our original approach. We turned our attention to study an aspect of a more traditional approach to distinguishing documents. Latent Dirichlet Allocation (LDA) turns documents into bags-of-words then into mixture-model points. A distance function is used to cluster groups of points to discover relatedness between documents. We performed a geometric and algebraic analysis of the most popular distance functions and made some significant and surprising discoveries, described in a separate technical report.

  16. Neurons to algorithms LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Rothganger, Fredrick H.; Aimone, James Bradley; Warrender, Christina E.; Trumbo, Derek

    2013-09-01

    Over the last three years the Neurons to Algorithms (N2A) LDRD project teams has built infrastructure to discover computational structures in the brain. This consists of a modeling language, a tool that enables model development and simulation in that language, and initial connections with the Neuroinformatics community, a group working toward similar goals. The approach of N2A is to express large complex systems like the brain as populations of a discrete part types that have specific structural relationships with each other, along with internal and structural dynamics. Such an evolving mathematical system may be able to capture the essence of neural processing, and ultimately of thought itself. This final report is a cover for the actual products of the project: the N2A Language Specification, the N2A Application, and a journal paper summarizing our methods.

  17. Final report for %22High performance computing for advanced national electric power grid modeling and integration of solar generation resources%22, LDRD Project No. 149016.

    Energy Technology Data Exchange (ETDEWEB)

    Reno, Matthew J.; Riehm, Andrew Charles; Hoekstra, Robert John; Munoz-Ramirez, Karina; Stamp, Jason Edwin; Phillips, Laurence R.; Adams, Brian M.; Russo, Thomas V.; Oldfield, Ron A.; McLendon, William Clarence, III; Nelson, Jeffrey Scott; Hansen, Clifford W.; Richardson, Bryan T.; Stein, Joshua S.; Schoenwald, David Alan; Wolfenbarger, Paul R.

    2011-02-01

    Design and operation of the electric power grid (EPG) relies heavily on computational models. High-fidelity, full-order models are used to study transient phenomena on only a small part of the network. Reduced-order dynamic and power flow models are used when analysis involving thousands of nodes are required due to the computational demands when simulating large numbers of nodes. The level of complexity of the future EPG will dramatically increase due to large-scale deployment of variable renewable generation, active load and distributed generation resources, adaptive protection and control systems, and price-responsive demand. High-fidelity modeling of this future grid will require significant advances in coupled, multi-scale tools and their use on high performance computing (HPC) platforms. This LDRD report demonstrates SNL's capability to apply HPC resources to these 3 tasks: (1) High-fidelity, large-scale modeling of power system dynamics; (2) Statistical assessment of grid security via Monte-Carlo simulations of cyber attacks; and (3) Development of models to predict variability of solar resources at locations where little or no ground-based measurements are available.

  18. Building Connecticut's clinical biodosimetry laboratory surge capacity to mitigate the health consequences of radiological and nuclear disasters: A collaborative approach between the state biodosimetry laboratory and Connecticut's medical infrastructure

    International Nuclear Information System (INIS)

    Biodosimetry, based on the analysis of dicentric chromosomes in circulating mononuclear cells, is considered the 'gold standard' for estimating radiation dose and is used to make informed decisions regarding the medical management of irradiated persons. This paper describes the development of biodosimetry laboratory surge capacity for the health consequences of radiological and nuclear disasters in Connecticut, including: (1) establishment of the Biodosimetry Laboratory for the timely assessment of radiation dosage in biodosimetry specimens; (2) identification of clinical laboratories qualified and willing to process biodosimetry specimens from a large number of victims; (3) training of clinical laboratorians in initial biodosimetry specimen processing; and (4) conducting a functional drill that evaluated the effectiveness of these elements. Descriptive information was obtained from: (1) personal observations; (2) a needs assessment of clinical laboratories in Connecticut; (3) records from a training program of clinical laboratorians in biodosimetry specimen processing that was developed and provided by the Yale New Haven Center for Emergency Preparedness and Disaster Response; and (4) records from a statewide functional drill in biodosimetry specimen processing that was developed and conducted by the State of Connecticut Biodosimetry Laboratory. A needs assessment of clinical laboratories in Connecticut identified 30 of 32 clinical laboratories qualified and willing to perform initial biodosimetry specimen processing. Currently, 79 clinical laboratorians in 19 of these qualified clinical laboratories have been trained in biodosimetry specimen processing. A functional exercise was conducted involving 37 of these trained clinical laboratorians in 18 qualified laboratories as well as the Biodosimetry Laboratory. The average turnaround time for biodosimetry specimen processing in this drill was 199 min. Exercise participants provided feedback which will be used to

  19. Evaluating the Special Needs of The Military for Radiation Biodosimetry for Tactical Warfare Against Deployed Troops: Comparing Military to Civilian Needs for Biodosimetry Methods.

    Science.gov (United States)

    Flood, Ann Barry; Ali, Arif N; Boyle, Holly K; Du, Gaixin; Satinsky, Victoria A; Swarts, Steven G; Williams, Benjamin B; Demidenko, Eugene; Schreiber, Wilson; Swartz, Harold M

    2016-08-01

    The aim of this paper is to delineate characteristics of biodosimetry most suitable for assessing individuals who have potentially been exposed to significant radiation from a nuclear device explosion when the primary population targeted by the explosion and needing rapid assessment for triage is civilians vs. deployed military personnel. The authors first carry out a systematic analysis of the requirements for biodosimetry to meet the military's needs to assess deployed troops in a warfare situation, which include accomplishing the military mission. Then the military's special capabilities to respond and carry out biodosimetry for deployed troops in warfare are compared and contrasted systematically, in contrast to those available to respond and conduct biodosimetry for civilians who have been targeted by terrorists, for example. Then the effectiveness of different biodosimetry methods to address military vs. civilian needs and capabilities in these scenarios was compared and, using five representative types of biodosimetry with sufficient published data to be useful for the simulations, the number of individuals are estimated who could be assessed by military vs. civilian responders within the timeframe needed for triage decisions. Analyses based on these scenarios indicate that, in comparison to responses for a civilian population, a wartime military response for deployed troops has both more complex requirements for and greater capabilities to use different types of biodosimetry to evaluate radiation exposure in a very short timeframe after the exposure occurs. Greater complexity for the deployed military is based on factors such as a greater likelihood of partial or whole body exposure, conditions that include exposure to neutrons, and a greater likelihood of combined injury. These simulations showed, for both the military and civilian response, that a very fast rate of initiating the processing (24,000 d) is needed to have at least some methods capable of

  20. Evaluating the Special Needs of The Military for Radiation Biodosimetry for Tactical Warfare Against Deployed Troops: Comparing Military to Civilian Needs for Biodosimetry Methods.

    Science.gov (United States)

    Flood, Ann Barry; Ali, Arif N; Boyle, Holly K; Du, Gaixin; Satinsky, Victoria A; Swarts, Steven G; Williams, Benjamin B; Demidenko, Eugene; Schreiber, Wilson; Swartz, Harold M

    2016-08-01

    The aim of this paper is to delineate characteristics of biodosimetry most suitable for assessing individuals who have potentially been exposed to significant radiation from a nuclear device explosion when the primary population targeted by the explosion and needing rapid assessment for triage is civilians vs. deployed military personnel. The authors first carry out a systematic analysis of the requirements for biodosimetry to meet the military's needs to assess deployed troops in a warfare situation, which include accomplishing the military mission. Then the military's special capabilities to respond and carry out biodosimetry for deployed troops in warfare are compared and contrasted systematically, in contrast to those available to respond and conduct biodosimetry for civilians who have been targeted by terrorists, for example. Then the effectiveness of different biodosimetry methods to address military vs. civilian needs and capabilities in these scenarios was compared and, using five representative types of biodosimetry with sufficient published data to be useful for the simulations, the number of individuals are estimated who could be assessed by military vs. civilian responders within the timeframe needed for triage decisions. Analyses based on these scenarios indicate that, in comparison to responses for a civilian population, a wartime military response for deployed troops has both more complex requirements for and greater capabilities to use different types of biodosimetry to evaluate radiation exposure in a very short timeframe after the exposure occurs. Greater complexity for the deployed military is based on factors such as a greater likelihood of partial or whole body exposure, conditions that include exposure to neutrons, and a greater likelihood of combined injury. These simulations showed, for both the military and civilian response, that a very fast rate of initiating the processing (24,000 d) is needed to have at least some methods capable of

  1. Development of Gene Expression Signatures for Practical Radiation Biodosimetry

    International Nuclear Information System (INIS)

    Purpose: In a large-scale radiologic emergency, estimates of exposure doses and radiation injury would be required for individuals without physical dosimeters. Current methods are inadequate for the task, so we are developing gene expression profiles for radiation biodosimetry. This approach could provide both an estimate of physical radiation dose and an indication of the extent of individual injury or future risk. Methods and Materials: We used whole genome microarray expression profiling as a discovery platform to identify genes with the potential to predict radiation dose across an exposure range relevant for medical decision making in a radiologic emergency. Human peripheral blood from 10 healthy donors was irradiated ex vivo, and global gene expression was measured both 6 and 24 h after exposure. Results: A 74-gene signature was identified that distinguishes between four radiation doses (0.5, 2, 5, and 8 Gy) and controls. More than one third of these genes are regulated by TP53. A nearest centroid classifier using these same 74 genes correctly predicted 98% of samples taken either 6 h or 24 h after treatment as unexposed, exposed to 0.5, 2, or ≥5 Gy. Expression patterns of five genes (CDKN1A, FDXR, SESN1, BBC3, and PHPT1) from this signature were also confirmed by real-time polymerase chain reaction. Conclusion: The ability of a single gene set to predict radiation dose throughout a window of time without need for individual pre-exposure controls represents an important advance in the development of gene expression for biodosimetry

  2. Final LDRD report :

    Energy Technology Data Exchange (ETDEWEB)

    Ambrosini, Andrea; Miller, James Edward; Allendorf, Mark D.; Coker, Eric Nicholas; Ermanoski, Ivan; Hogan, Roy E.,; McDaniel, Anthony H.

    2014-01-01

    Despite rapid progress, solar thermochemistry remains high risk; improvements in both active materials and reactor systems are needed. This claim is supported by studies conducted both prior to and as part of this project. Materials offer a particular large opportunity space as, until recently, very little effort apart from basic thermodynamic analysis was extended towards understanding this most fundamental component of a metal oxide thermochemical cycle. Without this knowledge, system design was hampered, but more importantly, advances in these crucial materials were rare and resulted more from intuition rather than detailed insight. As a result, only two basic families of potentially viable solid materials have been widely considered, each of which has significant challenges. Recent efforts towards applying an increased level of scientific rigor to the study of thermochemical materials have provided a much needed framework and insights toward developing the next generation of highly improved thermochemically active materials. The primary goal of this project was to apply this hard-won knowledge to rapidly advance the field of thermochemistry to produce a material within 2 years that is capable of yielding CO from CO2 at a 12.5 % reactor efficiency. Three principal approaches spanning a range of risk and potential rewards were pursued: modification of known materials, structuring known materials, and identifying/developing new materials for the application. A newly developed best-of-class material produces more fuel (9x more H2, 6x more CO) under milder conditions than the previous state of the art. Analyses of thermochemical reactor and system efficiencies and economics were performed and a new hybrid concept was reported. The larger case for solar fuels was also further refined and documented.

  3. Transportation Energy Pathways LDRD.

    Energy Technology Data Exchange (ETDEWEB)

    Barter, Garrett; Reichmuth, David; Westbrook, Jessica; Malczynski, Leonard A. [Sandia National Laboratories, Albuquerque, NM; Yoshimura, Ann S.; Peterson, Meghan; West, Todd H.; Manley, Dawn Kataoka; Guzman, Katherine Dunphy; Edwards, Donna M.; Hines, Valerie Ann-Peters

    2012-09-01

    This report presents a system dynamics based model of the supply-demand interactions between the USlight-duty vehicle (LDV) fleet, its fuels, and the corresponding primary energy sources through the year2050. An important capability of our model is the ability to conduct parametric analyses. Others have reliedupon scenario-based analysis, where one discrete set of values is assigned to the input variables and used togenerate one possible realization of the future. While these scenarios can be illustrative of dominant trendsand tradeoffs under certain circumstances, changes in input values or assumptions can have a significantimpact on results, especially when output metrics are associated with projections far into the future. Thistype of uncertainty can be addressed by using a parametric study to examine a range of values for the inputvariables, offering a richer source of data to an analyst.The parametric analysis featured here focuses on a trade space exploration, with emphasis on factors thatinfluence the adoption rates of electric vehicles (EVs), the reduction of GHG emissions, and the reduction ofpetroleum consumption within the US LDV fleet. The underlying model emphasizes competition between13 different types of powertrains, including conventional internal combustion engine (ICE) vehicles, flex-fuel vehicles (FFVs), conventional hybrids(HEVs), plug-in hybrids (PHEVs), and battery electric vehicles(BEVs).We find that many factors contribute to the adoption rates of EVs. These include the pace of technologicaldevelopment for the electric powertrain, battery performance, as well as the efficiency improvements inconventional vehicles. Policy initiatives can also have a dramatic impact on the degree of EV adoption. Theconsumer effective payback period, in particular, can significantly increase the market penetration rates ifextended towards the vehicle lifetime.Widespread EV adoption can have noticeable impact on petroleum consumption and greenhouse gas

  4. Enhanced Micellar Catalysis LDRD.

    Energy Technology Data Exchange (ETDEWEB)

    Betty, Rita G.; Tucker, Mark D; Taggart, Gretchen; Kinnan, Mark K.; Glen, Crystal Chanea; Rivera, Danielle; Sanchez, Andres; Alam, Todd Michael

    2012-12-01

    The primary goals of the Enhanced Micellar Catalysis project were to gain an understanding of the micellar environment of DF-200, or similar liquid CBW surfactant-based decontaminants, as well as characterize the aerosolized DF-200 droplet distribution and droplet chemistry under baseline ITW rotary atomization conditions. Micellar characterization of limited surfactant solutions was performed externally through the collection and measurement of Small Angle X-Ray Scattering (SAXS) images and Cryo-Transmission Electron Microscopy (cryo-TEM) images. Micellar characterization was performed externally at the University of Minnesotas Characterization Facility Center, and at the Argonne National Laboratory Advanced Photon Source facility. A micellar diffusion study was conducted internally at Sandia to measure diffusion constants of surfactants over a concentration range, to estimate the effective micelle diameter, to determine the impact of individual components to the micellar environment in solution, and the impact of combined components to surfactant phase behavior. Aerosolized DF-200 sprays were characterized for particle size and distribution and limited chemical composition. Evaporation rates of aerosolized DF-200 sprays were estimated under a set of baseline ITW nozzle test system parameters.

  5. LDRD final report : autotuning for scalable linear algebra.

    Energy Technology Data Exchange (ETDEWEB)

    Heroux, Michael Allen; Marker, Bryan (University of Texas at Austin, Austin, TX)

    2011-09-01

    This report summarizes the progress made as part of a one year lab-directed research and development (LDRD) project to fund the research efforts of Bryan Marker at the University of Texas at Austin. The goal of the project was to develop new techniques for automatically tuning the performance of dense linear algebra kernels. These kernels often represent the majority of computational time in an application. The primary outcome from this work is a demonstration of the value of model driven engineering as an approach to accurately predict and study performance trade-offs for dense linear algebra computations.

  6. SU-C-BRD-05: Non-Invasive in Vivo Biodosimetry in Radiotherapy Patients Using Electron Paramagnetic Resonance (EPR) Spectroscopy

    International Nuclear Information System (INIS)

    dose. With further development, a robust means of predicting delivered radiation dose from EPR measurements is expected. This project was funded by the Biomedical Advanced Research and Development Authority (BARDA) within the U.S. Department of Health and Human Services subcontracted through the Geisel School of Medicine at Dartmouth and by the Dartmouth Physically-Based Biodosimetry Center for Medical Countermeasures Against Radiation (Dart-Dose CMCR) Pilot Program

  7. SU-C-BRD-05: Non-Invasive in Vivo Biodosimetry in Radiotherapy Patients Using Electron Paramagnetic Resonance (EPR) Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Bahar, N; Roberts, K; Stabile, F; Mongillo, N; Decker, RD; Wilson, LD; Husain, Z; Contessa, J; Carlson, DJ [Yale University School of Medicine, New Haven, Connecticut (United States); Williams, BB; Flood, AB; Swartz, HM [Geisel Medical School at Dartmouth University, Hanover, New Hampshire (United States)

    2015-06-15

    dose. With further development, a robust means of predicting delivered radiation dose from EPR measurements is expected. This project was funded by the Biomedical Advanced Research and Development Authority (BARDA) within the U.S. Department of Health and Human Services subcontracted through the Geisel School of Medicine at Dartmouth and by the Dartmouth Physically-Based Biodosimetry Center for Medical Countermeasures Against Radiation (Dart-Dose CMCR) Pilot Program.

  8. ICF Program: LDRD-ER Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Glenzer, S H

    2004-02-05

    In the 01-ERD-107 LDRD-ER project, we have performed novel Thomson scattering experiments at the Trident and Omega laser facilities and provided high quality spectral data. These results have led to the development of the first quantitative understanding of laser-plasma interactions for NIF plasmas. For this purpose an green/ultraviolet probe laser, built for Nova in 1998 [1] and successfully used to measure both temperature and plasma wave amplitudes [2], has been deployed on Omega. The Thomson scattering diagnostics has been used twofold: (1) it provided independent measurements of the plasma electron and ion temperature, the plasma flow velocity, or the electron distribution function; (2) it provided measurements of the primary plasma wave and their secondary non-linear decay wave products. These experiments at Omega provide definitive quantitative results on the nonlinear saturation of stimulated Raman scattering for green (2{omega}) beams. In addition, the experiments on the Trident laser have led to a quantitative understanding of the stimulated Brillouin scattering in low-Z plasmas. A nonlinear frequency detuning model has successfully explained all the experimental observable including the SBS reflectivity. This model has been implemented into the laser-plasma interaction code pF3D as a tool to design and optimize NIF target experiments with SBS and SRS losses included. The development of quantitative models for SBS and SRS for various regimes has now been adopted as part of the WBS1 project within the ICF program.

  9. Canadian biodosimetry capacity for response to radiation emergencies

    International Nuclear Information System (INIS)

    In December 2001, Canada's response to the international political climate was launched by the creation of the Chemical, Biological, Radiological/Nuclear Research and Technology Initiative (CRTI). The National Biological Dosimetry Response Plan (NBDRP), established through partnering the expertise of three federal departments and one university, was created in response to this initiative. The NBDRP objectives were to develop a network of laboratories with expertise to perform biological dosimetry by cytogenetics and to investigate new technologies that may be applicable in the development of the new biodosimetry program. Since the creation of the NBDRP, Canada has made significant progress in enhancing expertise and resources to be better prepared for radiological/nuclear events. Through participation in exercises, the existing capacities were tested and recommendations for improvements were made. This paper describes the results from two exercises. The first exercise was designed to test the culturing, analysis, and reporting procedures within a single laboratory, and the second exercise was intended to test the capacity of the NBDRP. Future exercises will further challenge the network resulting in an improved national response capability

  10. Bio-dosimetry for radiation-exposed individuals

    International Nuclear Information System (INIS)

    Exposure of civil populations to genotoxic chemicals or radioactive hazard is an increased concern. It is not only an industrial risk (chemistry plant accident for example) but also a national security problem due to the threat of radiological and nuclear terrorism. It is important to anticipate the need of a bio-dosimetry tool aimed at identifying exposed population in the absence of acute syndrome, in order to assure the medical care that would prevent carcinogenic consequences. DNA repair is a bio-marker of exposure to geno-toxics in individuals. A DNA repair signature can be assessed from Peripheral Blood Mononuclear Cells (PBMCs) that reflects the exposure history of the individuals, using a functional enzymatic assay on bio-chip. A proof of concept was obtained using PBMCs from patients undergoing radiotherapy regimen. We identified two classes of responses among patients, if we except a very atypical signature in one patient that could reflect defects in DNA repair. Interestingly, repair of the major oxidative lesions increased during the course of the radiotherapy. We propose to implement this fast, quantitative, possibly automatized assay to identify bio-markers of exposure to geno-toxics and to validate the exposure bio-markers through ex vivo exposure of blood from volunteers. (authors)

  11. Fluorescence in situ hybridization with reference to biodosimetry: a review

    International Nuclear Information System (INIS)

    Many advances have taken place in the field of radiation biodosimetry in the recent past. Measurement of dicentric chromosome aberrations, was first developed and followed by micronuclei scoring. These, however, are unstable type aberrations and the cells carrying such aberrations are eliminated from the body in few years. They are therefore of use primarily in case of accidental exposures. The challenge is to measure the cumulative radiation exposure resulting from normal operations by measuring stable chromosome aberrations. Banding technique can measure stable chromosome aberration but require long time to analyse the banding pattern to study translocations. On the other hand fluorescence in situ hybridization (FISH) technique is sensitive, fast and easy to identify the translocations as the chromosomes involved in translocation are painted with different colours. This review brings out the requirements of various materials, their preparations, method of detection of fluorescence etc. for carrying out FISH. The experience of various laboratories using FISH in the monitoring of radiation absorbed dose is discussed. (author)

  12. Advancing the Fundamental Understanding of Fission: 2014 LDRD 20120077DR Review

    Energy Technology Data Exchange (ETDEWEB)

    White, Morgan C. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Tovesson, Fredrik K. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sierk, Arnold John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-02-06

    The following slides were presented as part of the LDRD 20120077DR Progress Appraisal Review held Tuesday, February 4, 2014. This is part of an ongoing project assessment the previous of which was documented in LA-UR-13-21182. This presentation documents the progress made against the goals agreed to as part of the 2013 review.

  13. Final Report for LDRD Project 02-ERD-069: Discovering the Unknown Mechanism(s) of Virulence in a BW, Class A Select Agent

    Energy Technology Data Exchange (ETDEWEB)

    Chain, P; Garcia, E

    2003-02-06

    The goal of this proposed effort was to assess the difficulty in identifying and characterizing virulence candidate genes in an organism for which very limited data exists. This was accomplished by first addressing the finishing phase of draft-sequenced F. tularensis genomes and conducting comparative analyses to determine the coding potential of each genome; to discover the differences in genome structure and content, and to identify potential genes whose products may be involved in the F. tularensis virulence process. The project was divided into three parts: (1) Genome finishing: This part involves determining the order and orientation of the consensus sequences of contigs obtained from Phrap assemblies of random draft genomic sequences. This tedious process consists of linking contig ends using information embedded in each sequence file that relates the sequence to the original cloned insert. Since inserts are sequenced from both ends, we can establish a link between these paired-ends in different contigs and thus order and orient contigs. Since these genomes carry numerous copies of insertion sequences, these repeated elements ''confuse'' the Phrap assembly program. It is thus necessary to break these contigs apart at the repeated sequences and individually join the proper flanking regions using paired-end information, or using results of comparisons against a similar genome. Larger repeated elements such as the small subunit ribosomal RNA operon require verification with PCR. Tandem repeats require manual intervention and typically rely on single nucleotide polymorphisms to be resolved. Remaining gaps require PCR reactions and sequencing. Once the genomes have been ''closed'', low quality regions are addressed by resequencing reactions. (2) Genome analysis: The final consensus sequences are processed by combining the results of three gene modelers: Glimmer, Critica and Generation. The final gene models are submitted to

  14. Final report on LDRD project : elucidating performance of proton-exchange-membrane fuel cells via computational modeling with experimental discovery and validation.

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Chao Yang (Pennsylvania State University, University Park, PA); Pasaogullari, Ugur (Pennsylvania State University, University Park, PA); Noble, David R.; Siegel, Nathan P.; Hickner, Michael A.; Chen, Ken Shuang

    2006-11-01

    In this report, we document the accomplishments in our Laboratory Directed Research and Development project in which we employed a technical approach of combining experiments with computational modeling and analyses to elucidate the performance of hydrogen-fed proton exchange membrane fuel cells (PEMFCs). In the first part of this report, we document our focused efforts on understanding water transport in and removal from a hydrogen-fed PEMFC. Using a transparent cell, we directly visualized the evolution and growth of liquid-water droplets at the gas diffusion layer (GDL)/gas flow channel (GFC) interface. We further carried out a detailed experimental study to observe, via direct visualization, the formation, growth, and instability of water droplets at the GDL/GFC interface using a specially-designed apparatus, which simulates the cathode operation of a PEMFC. We developed a simplified model, based on our experimental observation and data, for predicting the onset of water-droplet instability at the GDL/GFC interface. Using a state-of-the-art neutron imaging instrument available at NIST (National Institute of Standard and Technology), we probed liquid-water distribution inside an operating PEMFC under a variety of operating conditions and investigated effects of evaporation due to local heating by waste heat on water removal. Moreover, we developed computational models for analyzing the effects of micro-porous layer on net water transport across the membrane and GDL anisotropy on the temperature and water distributions in the cathode of a PEMFC. We further developed a two-phase model based on the multiphase mixture formulation for predicting the liquid saturation, pressure drop, and flow maldistribution across the PEMFC cathode channels. In the second part of this report, we document our efforts on modeling the electrochemical performance of PEMFCs. We developed a constitutive model for predicting proton conductivity in polymer electrolyte membranes and compared

  15. Hydrodynamics of maneuvering bodies: LDRD Final Report

    Science.gov (United States)

    Kempka, S. N.; Strickland, J. H.

    1994-01-01

    The objective of the 'Hydrodynamics of Maneuvering Bodies' LDRD project was to develop a Lagrangian, vorticity-based numerical simulation of the fluid dynamics associated with a maneuvering submarine. Three major tasks were completed. First, a vortex model to simulate the wake behind a maneuvering submarine was completed, assuming the flow to be inviscid and of constant density. Several simulations were performed for a dive maneuver, each requiring less than 20 cpu seconds on a workstation. The technical details of the model and the simulations are described in a separate document, but are reviewed herein. Second, a gridless method to simulate diffusion processes was developed that has significant advantages over previous Lagrangian diffusion models. In this model, viscous diffusion of vorticity is represented by moving vortices at a diffusion velocity, and expanding the vortices as specified by the kinematics for a compressible velocity field. This work was also documented previously and is only reviewed herein. The third major task completed was the development of a vortex model to describe inviscid internal wave phenomena and is the focus of this document. Internal wave phenomena in the stratified ocean can affect an evolving wake and thus, must be considered for naval applications. The vortex model for internal wave phenomena includes a new formulation for the generation of vorticity due to fluid density variations and a vortex adoption algorithm that allows solutions to be carried to much longer times than previous investigations. Since many practical problems require long-time solutions, this new adoption algorithm is a significant step toward making vortex methods applicable to practical problems. Several simulations are described and compared with previous results to validate and show the advantages of the new model. An overview of this project is also included.

  16. Hydrodynamics of maneuvering bodies: LDRD final report

    Energy Technology Data Exchange (ETDEWEB)

    Kempka, S.N.; Strickland, J.H.

    1994-01-01

    The objective of the ``Hydrodynamics of Maneuvering Bodies`` LDRD project was to develop a Lagrangian, vorticity-based numerical simulation of the fluid dynamics associated with a maneuvering submarine. Three major tasks were completed. First, a vortex model to simulate the wake behind a maneuvering submarine was completed, assuming the flow to be inviscid and of constant density. Several simulations were performed for a dive maneuver, each requiring less than 20 cpu seconds on a workstation. The technical details of the model and the simulations are described in a separate document, but are reviewed herein. Second, a gridless method to simulate diffusion processes was developed that has significant advantages over previous Lagrangian diffusion models. In this model, viscous diffusion of vorticity is represented by moving vortices at a diffusion velocity, and expanding the vortices as specified by the kinematics for a compressible velocity field. This work has also been documented previously, and is only reviewed herein. The third major task completed was the development of a vortex model to describe inviscid internal wave phenomena, and is the focus of this document. Internal wave phenomena in the stratified ocean can affect an evolving wake, and thus must be considered for naval applications. The vortex model for internal wave phenomena includes a new formulation for the generation of vorticity due to fluid density variations, and a vortex adoption algorithm that allows solutions to be carried to much longer times than previous investigations. Since many practical problems require long-time solutions, this new adoption algorithm is a significant step toward making vortex methods applicable to practical problems. Several simulations are described and compared with previous results to validate and show the advantages of the new model. An overview of this project is also included.

  17. Evaluation on Reproducibility of Space Radiation Generator and on Biodosimetry of Exposure to Space Radiation

    International Nuclear Information System (INIS)

    This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with references. And second part is establishment of biodosimetry for space radiation exposure using cellular transformation activity and micronuclei production. These data may give the direction to future research fields in space radiation biology

  18. 77 FR 41417 - Regulatory Science Considerations for Medical Countermeasure Radiation Biodosimetry Devices

    Science.gov (United States)

    2012-07-13

    ... performance evaluation challenges identified by FDA, (3) specific technology considerations in radiation... radiation biodosimeter be assessed? G. What challenges does the use of novel technologies bring to radiation... Radiation Biodosimetry Devices AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public...

  19. Efficient Probability of Failure Calculations for QMU using Computational Geometry LDRD 13-0144 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Scott A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ebeida, Mohamed Salah [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Romero, Vicente J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Swiler, Laura Painton [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rushdi, Ahmad A. [Univ. of Texas, Austin, TX (United States); Abdelkader, Ahmad [Univ. of Maryland, College Park, MD (United States)

    2015-09-01

    This SAND report summarizes our work on the Sandia National Laboratory LDRD project titled "Efficient Probability of Failure Calculations for QMU using Computational Geometry" which was project #165617 and proposal #13-0144. This report merely summarizes our work. Those interested in the technical details are encouraged to read the full published results, and contact the report authors for the status of the software and follow-on projects.

  20. Hybrid methods for cybersecurity analysis : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Warren Leon,; Dunlavy, Daniel M.

    2014-01-01

    Early 2010 saw a signi cant change in adversarial techniques aimed at network intrusion: a shift from malware delivered via email attachments toward the use of hidden, embedded hyperlinks to initiate sequences of downloads and interactions with web sites and network servers containing malicious software. Enterprise security groups were well poised and experienced in defending the former attacks, but the new types of attacks were larger in number, more challenging to detect, dynamic in nature, and required the development of new technologies and analytic capabilities. The Hybrid LDRD project was aimed at delivering new capabilities in large-scale data modeling and analysis to enterprise security operators and analysts and understanding the challenges of detection and prevention of emerging cybersecurity threats. Leveraging previous LDRD research e orts and capabilities in large-scale relational data analysis, large-scale discrete data analysis and visualization, and streaming data analysis, new modeling and analysis capabilities were quickly brought to bear on the problems in email phishing and spear phishing attacks in the Sandia enterprise security operational groups at the onset of the Hybrid project. As part of this project, a software development and deployment framework was created within the security analyst work ow tool sets to facilitate the delivery and testing of new capabilities as they became available, and machine learning algorithms were developed to address the challenge of dynamic threats. Furthermore, researchers from the Hybrid project were embedded in the security analyst groups for almost a full year, engaged in daily operational activities and routines, creating an atmosphere of trust and collaboration between the researchers and security personnel. The Hybrid project has altered the way that research ideas can be incorporated into the production environments of Sandias enterprise security groups, reducing time to deployment from months and

  1. Final LDRD report : advanced plastic scintillators for neutron detection.

    Energy Technology Data Exchange (ETDEWEB)

    Vance, Andrew L.; Mascarenhas, Nicholas; O' Bryan, Greg; Mrowka, Stanley

    2010-09-01

    This report summarizes the results of a one-year, feasibility-scale LDRD project that was conducted with the goal of developing new plastic scintillators capable of pulse shape discrimination (PSD) for neutron detection. Copolymers composed of matrix materials such as poly(methyl methacrylate) (PMMA) and blocks containing trans-stilbene (tSB) as the scintillator component were prepared and tested for gamma/neutron response. Block copolymer synthesis utilizing tSBMA proved unsuccessful so random copolymers containing up to 30% tSB were prepared. These copolymers were found to function as scintillators upon exposure to gamma radiation; however, they did not exhibit PSD when exposed to a neutron source. This project, while falling short of its ultimate goal, demonstrated the possible utility of single-component, undoped plastics as scintillators for applications that do not require PSD.

  2. Tracking of Nuclear Production using Indigenous Species: Final LDRD Report

    Energy Technology Data Exchange (ETDEWEB)

    Alam, Todd Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Dept. of Electronic and Nanostructured Materials; Alam, Mary Kathleen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Energetics Characterization Dept.; McIntyre, Sarah K. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Dept. of Electronic and Nanostructured Materials; Volk, David [Univ. of Texas, Galveston, TX (United States). Medical Branch; Neerathilingam, Muniasamy [Univ. of Texas, Galveston, TX (United States). Medical Branch; Luxon, Bruce A. [Univ. of Texas, Galveston, TX (United States). Medical Branch; Ansari, G. A. Shakeel [Univ. of Texas, Galveston, TX (United States). Medical Branch

    2009-10-01

    Our LDRD research project sought to develop an analytical method for detection of chemicals used in nuclear materials processing. Our approach is distinctly different than current research involving hardware based sensors. By utilizing the response of indigenous species of plants and/or animals surrounding (or within) a nuclear processing facility, we propose tracking 'suspicious molecules' relevant to nuclear materials processing. As proof of concept, we have examined TBP, tributylphosphate, used in uranium enrichment as well as plutonium extraction from spent nuclear fuels. We will compare TBP to the TPP (triphenylphosphate) analog to determine the uniqueness of the metabonomic response. We show that there is a unique metabonomic response within our animal model to TBP. The TBP signature can further be delineated from that of TPP. We have also developed unique methods of instrumental transfer for metabonomic data sets.

  3. Development and application of the PCC biodosimetry method in emergency preparedness

    Energy Technology Data Exchange (ETDEWEB)

    Stricklin, D. (Swedish Defence Research Agency, FOI (Sweden)); Lindholm, C. (Finnish Radiation and Nuclear Safety Authority, STUK (Finland)); Jaworska, A. (Norwegian Radiation Protection Authority, NRPA (Norway))

    2008-07-15

    A method for biological assessment of radiation dose for specific application in emergency preparedness was developed. Premature chromosome condensation (PCC) was investigated to provide a potentially faster means of analysis and the ability to assess higher doses than with the dicentric assay which is routinely applied in biodosimetry today. A review of existing methods was made, followed by experiments determine optimal assay conditions, and evaluations to determination of optimal conditions and the most appropriate endpoints for analyses. Twelve different experimental conditions were examined with four different evaluation approaches. Aspects during optimization such as practicality, speed, and reliability were considered. The conclusion from these studies was a PCC protocol utilizing okadaic acid for induction of PCC cells in stimulated lymphocytes but without the use of colcemid for metaphase arrest with the subsequent evaluation of ring chromosomes. Well-defined criteria were established for evaluation of PCC cells and ring chromosome aberrations. An inter-calibration was made by comparing assessment of ring chromosomes between all three laboratories. Agreement was made to count only rings with observable open spaces or large, obvious rings without open spaces. Finally a dose response curve for the PCC method was prepared and a comparison of the PCC method to the traditional dicentric assay in triage mode was made. The triage method requires a minimal number of evaluations so that categorization of high, medium and low doses may be made in an emergency situation where large numbers of people should be evaluated. The comparison of the PCC method with the dicentric assay triage method indicated that the PCC assay performed superior to the dicentric assay for evaluation of samples at higher doses, however, the dicentric assay appeared to provide more accurate dose assessment at lower doses. This project suggests a PCC assay method for biological dose estimates

  4. LDRD final report : robust analysis of large-scale combinatorial applications.

    Energy Technology Data Exchange (ETDEWEB)

    Carr, Robert D.; Morrison, Todd (University of Colorado, Denver, CO); Hart, William Eugene; Benavides, Nicolas L. (Santa Clara University, Santa Clara, CA); Greenberg, Harvey J. (University of Colorado, Denver, CO); Watson, Jean-Paul; Phillips, Cynthia Ann

    2007-09-01

    Discrete models of large, complex systems like national infrastructures and complex logistics frameworks naturally incorporate many modeling uncertainties. Consequently, there is a clear need for optimization techniques that can robustly account for risks associated with modeling uncertainties. This report summarizes the progress of the Late-Start LDRD 'Robust Analysis of Largescale Combinatorial Applications'. This project developed new heuristics for solving robust optimization models, and developed new robust optimization models for describing uncertainty scenarios.

  5. FY07 LDRD Final Report Precision, Split Beam, Chirped-Pulse, Seed Laser Technology

    Energy Technology Data Exchange (ETDEWEB)

    Dawson, J W; Messerly, M J; Phan, H H; Crane, J K; Beach, R J; Siders, C W; Barty, C J

    2009-11-12

    The goal of this LDRD ER was to develop a robust and reliable technology to seed high-energy laser systems with chirped pulses that can be amplified to kilo-Joule energies and recompressed to sub-picosecond pulse widths creating extremely high peak powers suitable for petawatt class physics experiments. This LDRD project focused on the development of optical fiber laser technologies compatible with the current long pulse National Ignition Facility (NIF) seed laser. New technologies developed under this project include, high stability mode-locked fiber lasers, fiber based techniques for reduction of compressed pulse pedestals and prepulses, new compact stretchers based on chirped fiber Bragg gratings (CFBGs), new techniques for manipulation of chirped pulses prior to amplification and new high-energy fiber amplifiers. This project was highly successful and met virtually all of its goals. The National Ignition Campaign has found the results of this work to be very helpful. The LDRD developed system is being employed in experiments to engineer the Advanced Radiographic Capability (ARC) front end and the fully engineered version of the ARC Front End will employ much of the technology and techniques developed here.

  6. Multi-attribute criteria applied to electric generation energy system analysis LDRD.

    Energy Technology Data Exchange (ETDEWEB)

    Kuswa, Glenn W.; Tsao, Jeffrey Yeenien; Drennen, Thomas E.; Zuffranieri, Jason V.; Paananen, Orman Henrie; Jones, Scott A.; Ortner, Juergen G. (DLR, German Aerospace, Cologne); Brewer, Jeffrey D.; Valdez, Maximo M.

    2005-10-01

    This report began with a Laboratory-Directed Research and Development (LDRD) project to improve Sandia National Laboratories multidisciplinary capabilities in energy systems analysis. The aim is to understand how various electricity generating options can best serve needs in the United States. The initial product is documented in a series of white papers that span a broad range of topics, including the successes and failures of past modeling studies, sustainability, oil dependence, energy security, and nuclear power. Summaries of these projects are included here. These projects have provided a background and discussion framework for the Energy Systems Analysis LDRD team to carry out an inter-comparison of many of the commonly available electric power sources in present use, comparisons of those options, and efforts needed to realize progress towards those options. A computer aid has been developed to compare various options based on cost and other attributes such as technological, social, and policy constraints. The Energy Systems Analysis team has developed a multi-criteria framework that will allow comparison of energy options with a set of metrics that can be used across all technologies. This report discusses several evaluation techniques and introduces the set of criteria developed for this LDRD.

  7. Laser Spray Fabrication for Net-Shape Rapid Product Realization LDRD

    Energy Technology Data Exchange (ETDEWEB)

    Atwood, C.L.; Ensz, M.T.; Greene, D.L.; Griffith, M.L.; Harwell, L.D.; Jeantette, F.P.; Keicher, D.M.; Oliver, M.S.; Reckaway, D.E.; Romero, J.A.; Schlienger, M.E.; Smugeresky, J.D.

    1999-04-01

    The primary purpose of this LDRD project was to characterize the laser deposition process and determine the feasibility of fabricating complex near-net shapes directly from a CAD solid model. Process characterization provided direction in developing a system to fabricate complex shapes directly from a CAD solid model. Our goal for this LDRD was to develop a system that is robust and provides a significant advancement to existing technologies (e.g., polymeric-based rapid prototyping, laser welding). Development of the process will allow design engineers to produce functional models of their designs directly from CAD files. The turnaround time for complex geometrical shaped parts will be hours instead of days and days instead of months. With reduced turnaround time, more time can be spent on the product-design phase to ensure that the best component design is achieved. Maturation of this technology will revolutionize the way the world produces structural components.

  8. LDRD Final Report: Surrogate Nuclear Reactions and the Origin of the Heavy Elements (04-ERD-057)

    Energy Technology Data Exchange (ETDEWEB)

    Escher, J E; Bernstein, L A; Bleuel, D; Burke, J; Church, J A; Dietrich, F S; Forssen, C; Gueorguiev, V; Hoffman, R D

    2007-02-23

    Research carried out in the framework of the LDRD project ''Surrogate Nuclear Reactions and the Origin of the Heavy Elements'' (04-ERD-057) is summarized. The project was designed to address the challenge of determining cross sections for nuclear reactions involving unstable targets, with a particular emphasis on reactions that play a key role in the production of the elements between Iron and Uranium. This report reviews the motivation for the research, introduces the approach employed to address the problem, and summarizes the resulting scientific insights, technical findings, and related accomplishments.

  9. Retrospective biodosimetry using translocation frequency in a stable cell of occupationally exposed to ionizing radiation

    International Nuclear Information System (INIS)

    Two cases of hematological malignancies were reported in an industrial radiography company over a year, which were reasonably suspected of being consequences of prolonged exposure to ionizing radiation because of the higher incidence than expected in the general population. We analyzed chromosomal aberrations in the peripheral blood lymphocytes from the other workers who had been working under similar circumstances as the patients in the company. Among the subjects tested, 10 workers who belonged to the highest band were followed up periodically for 1.5 years since the first analysis. The aim of this study was to clarify pertinence of translocation analysis to an industrial set-up where chronic exposure was commonly expected. To be a useful tool for a retrospective biodosimetry, the aberrations need to be persistent for a decade or longer. Therefore we calculated the decline rates and half-lives of frequency for both a reciprocal translocation and a dicentric chromosome and compared them. In this study, while the frequency of reciprocal translocations was maintained at the initial level, dicentric chromosomes were decreased to 46.9% (31.0–76.5) of the initial frequency over the follow-up period. Our results support the long-term stability of reciprocal translocation through the cell cycle and validate the usefulness of translocation analysis as a retrospective biodosimetry for cases of occupational exposure. (author)

  10. Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model

    Directory of Open Access Journals (Sweden)

    Christophe E. Redon

    2013-07-01

    Full Text Available There is a paucity of large animal models to study both the extent and the health risk of ionizing radiation exposure in humans. One promising candidate for such a model is the minipig. Here, we evaluate the minipig for its potential in γ-H2AX-based biodosimetry after exposure to ionizing radiation using both Cs137 and Co60 sources. γ-H2AX foci were enumerated in blood lymphocytes and normal fibroblasts of human and porcine origin after ex vivo g-ray irradiation. DNA double-strand break repair kinetics in minipig blood lymphocytes and fibroblasts, based on the γ-H2AX assay, were similar to those observed in their human counterparts. To substantiate the similarity observed between the human and minipig we show that minipig fibroblast radiosensitivity was similar to that observed with human fibroblasts. Finally, a strong γ-H2AX induction was observed in blood lymphocytes following minipig total body irradiation. Significant responses were detected 3 days after 1.8 Gy and 1 week after 3.8 and 5 Gy with residual γ-H2AX foci proportional to the initial radiation doses. These findings show that the Gottingen minipig provides a useful in vivo model for validation of γ-H2AX biodosimetry for dose assessment in humans.

  11. Small space object imaging : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Ackermann, Mark R.; Valley, Michael T.; Kearney, Sean Patrick

    2009-10-01

    We report the results of an LDRD effort to investigate new technologies for the identification of small-sized (mm to cm) debris in low-earth orbit. This small-yet-energetic debris presents a threat to the integrity of space-assets worldwide and represents significant security challenge to the international community. We present a nonexhaustive review of recent US and Russian efforts to meet the challenges of debris identification and removal and then provide a detailed description of joint US-Russian plans for sensitive, laser-based imaging of small debris at distances of hundreds of kilometers and relative velocities of several kilometers per second. Plans for the upcoming experimental testing of these imaging schemes are presented and a preliminary path toward system integration is identified.

  12. Obstacle detection for autonomous navigation : an LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Padilla, Denise D.

    2004-03-01

    This report summarizes the analytical and experimental efforts for the Laboratory Directed Research and Development (LDRD) project entitled 'Obstacle Detection for Autonomous Navigation'. The principal goal of this project was to develop a mathematical framework for obstacle detection. The framework provides a basis for solutions to many complex obstacle detection problems critical to successful autonomous navigation. Another goal of this project was to characterize sensing requirements in terms of physical characteristics of obstacles, vehicles, and terrain. For example, a specific vehicle traveling at a specific velocity over a specific terrain requires a sensor with a certain range of detection, resolution, field-of-view, and sufficient sensitivity to specific obstacle characteristics. In some cases, combinations of sensors were required to distinguish between different hazardous obstacles and benign terrain. In our framework, the problem was posed as a multidimensional, multiple-hypothesis, pattern recognition problem. Features were extracted from selected sensors that allow hazardous obstacles to be distinguished from benign terrain and other types of obstacles. Another unique thrust of this project was to characterize different terrain classes with respect to both positive (e.g., rocks, trees, fences) and negative (e.g., holes, ditches, drop-offs) obstacles. The density of various hazards per square kilometer was statistically quantified for different terrain categories (e.g., high desert, ponderosa forest, and prairie). This quantification reflects the scale, or size, and mobility of different types of vehicles. The tradeoffs between obstacle detection, position location, path planning, and vehicle mobility capabilities were also to be characterized.

  13. Minisatellite mutations and retrospective biodosimetry of population living close to the Semipalatinsk nuclear test site

    Energy Technology Data Exchange (ETDEWEB)

    Lindholm, C.; Bersimbacv, R. I.; Dubrova, Y. E.; Hulten, M.; Bigbee, W. I.; Murphy, B. P.; Koivistoinen, A.; Tankimonova, M.; Mamyrbaeva, Z.; Djansugarova, L.; Mustonen, R.; Salomaa, S.

    2004-07-01

    The objectives of the study were to determine minisatellite mutation rates in families in three generations and to perform retrospective biodosimetry of individuals in these families living close to the Semipalatinsk nuclear test site in Kazakhstan. The oldes generation (Po) lived in the area at the time of the first Soviet nuclear test in 1949 whereas the younger generations (F1,F2) were exposed to smaller doses from the residual fallout and later tests. Matched control families in three generations living in non-contamianted areas were analysed in parallel. The retrospective biodosimetry comprehended two endpoints; chromosomal translocations determined by FISH chromosome painting and the glycophorin A (GPA) somatic mutation assay. The minisatellite mutation rate in the cohort of P0 parents was 1-8-fold higher than in the control non-exposed population. Moreover, the minisatellite mutatin rate in the cohort of f1 parents from the exposed area showed a significant negative correlation with with the year of birth, fully consistent with the decay of radioisotopes after the cessation of surface and atmospheric nuclear tests. The results from the FISH painting analysis showed similar translocation frequencies in the Semipalatinsk cohort and the control group. Based on the FISH results it can be concluded that the P0 generation has received a cumulative mean dose of less than 0.5 Gy. The GPA assay did not reveal significant diffrences in the variant cell frequencies for all subjects from the Semipalatinsk area compared with the matched controls. However, a significant increase (P<0.05) of the mean allele-loss {phi}N variant frequency was observed among the exposed P0 generation in comparison to controls. Considering the sensitivity of the GPA assay, the results suggest that the mean dose to the P0 generation of the affected villages was relatively low and in accordance to the results obtained using FISH. (Author) 17 refs.

  14. LDRD final report : a lightweight operating system for multi-core capability class supercomputers.

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, Suzanne Marie; Hudson, Trammell B. (OS Research); Ferreira, Kurt Brian; Bridges, Patrick G. (University of New Mexico); Pedretti, Kevin Thomas Tauke; Levenhagen, Michael J.; Brightwell, Ronald Brian

    2010-09-01

    The two primary objectives of this LDRD project were to create a lightweight kernel (LWK) operating system(OS) designed to take maximum advantage of multi-core processors, and to leverage the virtualization capabilities in modern multi-core processors to create a more flexible and adaptable LWK environment. The most significant technical accomplishments of this project were the development of the Kitten lightweight kernel, the co-development of the SMARTMAP intra-node memory mapping technique, and the development and demonstration of a scalable virtualization environment for HPC. Each of these topics is presented in this report by the inclusion of a published or submitted research paper. The results of this project are being leveraged by several ongoing and new research projects.

  15. Building more powerful less expensive supercomputers using Processing-In-Memory (PIM) LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, Richard C.

    2009-09-01

    This report details the accomplishments of the 'Building More Powerful Less Expensive Supercomputers Using Processing-In-Memory (PIM)' LDRD ('PIM LDRD', number 105809) for FY07-FY09. Latency dominates all levels of supercomputer design. Within a node, increasing memory latency, relative to processor cycle time, limits CPU performance. Between nodes, the same increase in relative latency impacts scalability. Processing-In-Memory (PIM) is an architecture that directly addresses this problem using enhanced chip fabrication technology and machine organization. PIMs combine high-speed logic and dense, low-latency, high-bandwidth DRAM, and lightweight threads that tolerate latency by performing useful work during memory transactions. This work examines the potential of PIM-based architectures to support mission critical Sandia applications and an emerging class of more data intensive informatics applications. This work has resulted in a stronger architecture/implementation collaboration between 1400 and 1700. Additionally, key technology components have impacted vendor roadmaps, and we are in the process of pursuing these new collaborations. This work has the potential to impact future supercomputer design and construction, reducing power and increasing performance. This final report is organized as follow: this summary chapter discusses the impact of the project (Section 1), provides an enumeration of publications and other public discussion of the work (Section 1), and concludes with a discussion of future work and impact from the project (Section 1). The appendix contains reprints of the refereed publications resulting from this work.

  16. LDRD Final Report: Global Optimization for Engineering Science Problems

    Energy Technology Data Exchange (ETDEWEB)

    HART,WILLIAM E.

    1999-12-01

    For a wide variety of scientific and engineering problems the desired solution corresponds to an optimal set of objective function parameters, where the objective function measures a solution's quality. The main goal of the LDRD ''Global Optimization for Engineering Science Problems'' was the development of new robust and efficient optimization algorithms that can be used to find globally optimal solutions to complex optimization problems. This SAND report summarizes the technical accomplishments of this LDRD, discusses lessons learned and describes open research issues.

  17. Interface physics in microporous media : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Yaklin, Melissa A.; Knutson, Chad E.; Noble, David R.; Aragon, Alicia R.; Chen, Ken Shuang; Giordano, Nicholas J. (Purdue University, West Lafayette, IN); Brooks, Carlton, F.; Pyrak-Nolte, Laura J. (Purdue University, West Lafayette, IN); Liu, Yihong (Purdue University, West Lafayette, IN)

    2008-09-01

    This document contains a summary of the work performed under the LDRD project entitled 'Interface Physics in Microporous Media'. The presence of fluid-fluid interfaces, which can carry non-zero stresses, distinguishes multiphase flows from more readily understood single-phase flows. In this work the physics active at these interfaces has been examined via a combined experimental and computational approach. One of the major difficulties of examining true microporous systems of the type found in filters, membranes, geologic media, etc. is the geometric uncertainty. To help facilitate the examination of transport at the pore-scale without this complication, a significant effort has been made in the area of fabrication of both two-dimensional and three-dimensional micromodels. Using these micromodels, multiphase flow experiments have been performed for liquid-liquid and liquid-gas systems. Laser scanning confocal microscopy has been utilized to provide high resolution, three-dimensional reconstructions as well as time resolved, two-dimensional reconstructions. Computational work has focused on extending lattice Boltzmann (LB) and finite element methods for probing the interface physics at the pore scale. A new LB technique has been developed that provides over 100x speed up for steady flows in complex geometries. A new LB model has been developed that allows for arbitrary density ratios, which has been a significant obstacle in applying LB to air-water flows. A new reduced order model has been developed and implemented in finite element code for examining non-equilibrium wetting in microchannel systems. These advances will enhance Sandia's ability to quantitatively probe the rich interfacial physics present in microporous systems.

  18. Study of p53 protein expression levels from irradiated peripheral blood lymphocytes for biodosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Cavalcanti, M.B.; Fernandes, T.S. [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Energia Nuclear; Amaral, A. [Universite Paris XII (UPXII) (France); Melo, J.A. [Centro de Radioterapia de Pernambuco (CERAPE), PE (Brazil); Neves, M.A.B.; Machado, C.G.F, E-mail: maribrayner@yahoo.com.br [Fundacao de Hematologia e Hemoterapia de Pernambuco, PE (Brazil)

    2005-07-01

    Biodosimetry can be defined as the investigation of radioinduced biological effects in order to correlate them with the absorbed dose. Scoring of unstable chromosomal aberrations and micronuclei, from in vitro irradiated peripheral blood lymphocytes, is commonly used for biodosimetry based on cytogenetic analysis. However, this method of analysis is time-consuming, which may represent a pitfall when fast investigation of a possible exposure to ionizing radiation (IR) is needed. The interaction of IR with the living cell can cause injuries in the DNA molecules. However, normal cells possess mechanisms of repair that are capable to correct those damages. During the repair process of the DNA various proteins are expressed. Among these proteins, p53 plays an important role. This protein is a transcription factor that helps in the maintenance of the genomic integrity. p53 protein is found into the cytoplasm in reduced concentrations and has a short average life. However, expression of p53 protein can be induced by DNA harmful radioinduced, which increases the concentration and the average life of this protein, making possible its detection. Thus, the correlation between the increasing of p53 expression and the irradiation may constitute a fast and reliable method of individual monitoring in cases of accidental or suspected exposures to IR. In this context, the objective of this research was to evaluate the p53 protein expression levels from lymphocytes of the human peripheral blood after in vitro irradiation. For this, samples of peripheral blood from healthy individuals were irradiated with known doses. Lymphocytes were separated on ficoll gradient by centrifugation and re-suspended at 1x 10{sub 6}/mL in RPMI medium enriched with fetal calf serum. Hence, lymphocytes were incubated in 5% CO{sub 2} at 37 deg C prior to the methodology of flow cytometry, using intranuclear antigens for the quantification of p53. In this report, the methodology performed and the results

  19. Idaho National Laboratory LDRD Annual Report FY 2012

    Energy Technology Data Exchange (ETDEWEB)

    Dena Tomchak

    2013-03-01

    This report provides a glimpse into our diverse research and development portfolio, wwhich encompasses both advanced nuclear science and technology and underlying technologies. IN keeping with the mission, INL's LDRD program fosters technical capabilities necessary to support current and future DOE-Office of Nuclear Energy research and development needs.

  20. Multi-target camera tracking, hand-off and display LDRD 158819 final report

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-10-01

    Modern security control rooms gather video and sensor feeds from tens to hundreds of cameras. Advanced camera analytics can detect motion from individual video streams and convert unexpected motion into alarms, but the interpretation of these alarms depends heavily upon human operators. Unfortunately, these operators can be overwhelmed when a large number of events happen simultaneously, or lulled into complacency due to frequent false alarms. This LDRD project has focused on improving video surveillance based security systems by changing the fundamental focus from the cameras to the targets being tracked. If properly integrated, more cameras shouldnt lead to more alarms, more monitors, more operators, and increased response latency but instead should lead to better information and more rapid response times. For the course of the LDRD we have been developing algorithms that takes live video imagery from multiple video cameras, identifies individual moving targets from the background imagery, and then displays the results in a single 3D interactive video. In this document we summarize the work in developing this multi-camera, multi-target system, including lessons learned, tools developed, technologies explored, and a description of currently capability.

  1. Multi-Target Camera Tracking, Hand-off and Display LDRD 158819 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Robotic and Security Systems Dept.

    2014-10-01

    Modern security control rooms gather video and sensor feeds from tens to hundreds of cameras. Advanced camera analytics can detect motion from individual video streams and convert unexpected motion into alarms, but the interpretation of these alarms depends heavily upon human operators. Unfortunately, these operators can be overwhelmed when a large number of events happen simultaneously, or lulled into complacency due to frequent false alarms. This LDRD project has focused on improving video surveillance based security systems by changing the fundamental focus from the cameras to the targets being tracked. If properly integrated, more cameras shouldn’t lead to more alarms, more monitors, more operators, and increased response latency but instead should lead to better information and more rapid response times. For the course of the LDRD we have been developing algorithms that takes live video imagery from multiple video cameras, identifies individual moving targets from the background imagery, and then displays the results in a single 3D interactive video. In this document we summarize the work in developing this multi-camera, multi-target system, including lessons learned, tools developed, technologies explored, and a description of currently capability.

  2. Multi-target camera tracking, hand-off and display LDRD 158819 final report

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-10-01

    Modern security control rooms gather video and sensor feeds from tens to hundreds of cameras. Advanced camera analytics can detect motion from individual video streams and convert unexpected motion into alarms, but the interpretation of these alarms depends heavily upon human operators. Unfortunately, these operators can be overwhelmed when a large number of events happen simultaneously, or lulled into complacency due to frequent false alarms. This LDRD project has focused on improving video surveillance-based security systems by changing the fundamental focus from the cameras to the targets being tracked. If properly integrated, more cameras shouldn't lead to more alarms, more monitors, more operators, and increased response latency but instead should lead to better information and more rapid response times. For the course of the LDRD we have been developing algorithms that takes live video imagery from multiple video cameras, identifies individual moving targets from the background imagery, and then displays the results in a single 3D interactive video. In this document we summarize the work in developing this multi-camera, multi-target system, including lessons learned, tools developed, technologies explored, and a description of currently capability.

  3. Multi-target camera tracking, hand-off and display LDRD 158819 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert J.

    2014-10-01

    Modern security control rooms gather video and sensor feeds from tens to hundreds of cameras. Advanced camera analytics can detect motion from individual video streams and convert unexpected motion into alarms, but the interpretation of these alarms depends heavily upon human operators. Unfortunately, these operators can be overwhelmed when a large number of events happen simultaneously, or lulled into complacency due to frequent false alarms. This LDRD project has focused on improving video surveillance based security systems by changing the fundamental focus from the cameras to the targets being tracked. If properly integrated, more cameras shouldnt lead to more alarms, more monitors, more operators, and increased response latency but instead should lead to better information and more rapid response times. For the course of the LDRD we have been developing algorithms that takes live video imagery from multiple video cameras, identifies individual moving targets from the background imagery, and then displays the results in a single 3D interactive video. In this document we summarize the work in developing this multi-camera, multi-target system, including lessons learned, tools developed, technologies explored, and a description of currently capability.

  4. A dose-response curve for biodosimetry from a 6 MV electron linear accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Lemos-Pinto, M.M.P.; Cadena, M.; Santos, N.; Fernandes, T.S.; Borges, E.; Amaral, A., E-mail: marcelazoo@yahoo.com.br [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Departamento de Energia Nuclear

    2015-10-15

    Biological dosimetry (biodosimetry) is based on the investigation of radiation-induced biological effects (biomarkers), mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical parameters, such as the type of ionizing radiation characterized by low or high linear energy transfer (LET) and dose rate. This study was designed to obtain dose calibration curves by scoring of dicentric chromosomes in peripheral blood lymphocytes irradiated in vitro with a 6 MV electron linear accelerator (Mevatron M, Siemens, USA). Two software programs, CABAS (Chromosomal Aberration Calculation Software) and Dose Estimate, were used to generate the curve. The two software programs are discussed; the results obtained were compared with each other and with other published low LET radiation curves. Both software programs resulted in identical linear and quadratic terms for the curve presented here, which was in good agreement with published curves for similar radiation quality and dose rates. (author)

  5. Micronucleus test for radiation biodosimetry in mass casualty events: Evaluation of visual and automated scoring

    International Nuclear Information System (INIS)

    In the case of a large-scale nuclear or radiological incidents a reliable estimate of dose is an essential tool for providing timely assessment of radiation exposure and for making life-saving medical decisions. Cytogenetics is considered as the 'gold standard' for biodosimetry. The dicentric analysis (DA) represents the most specific cytogenetic bioassay. The micronucleus test (MN) applied in interphase in peripheral lymphocytes is an alternative and simpler approach. A dose-effect calibration curve for the MN frequency in peripheral lymphocytes from 27 adult donors was established after in vitro irradiation at a dose range 0.15-8 Gy of 137Cs gamma rays (dose rate 6 Gy min-1). Dose prediction by visual scoring in a dose-blinded study (0.15-4.0 Gy) revealed a high level of accuracy (R = 0.89). The scoring of MN is time consuming and requires adequate skills and expertise. Automated image analysis is a feasible approach allowing to reduce the time and to increase the accuracy of the dose estimation decreasing the variability due to subjective evaluation. A good correlation (R = 0.705) between visual and automated scoring with visual correction was observed over the dose range 0-2 Gy. Almost perfect discrimination power for exposure to 1-2 Gy, and a satisfactory power for 0.6 Gy were detected. This threshold level can be considered sufficient for identification of sub lethally exposed individuals by automated CBMN assay.

  6. Retrospective on the Seniors' Council Tier 1 LDRD portfolio.

    Energy Technology Data Exchange (ETDEWEB)

    Ballard, William Parker

    2012-04-01

    This report describes the Tier 1 LDRD portfolio, administered by the Seniors Council between 2003 and 2011. 73 projects were sponsored over the 9 years of the portfolio at a cost of $10.5 million which includes $1.9M of a special effort in directed innovation targeted at climate change and cyber security. Two of these Tier 1 efforts were the seeds for the Grand Challenge LDRDs in Quantum Computing and Next Generation Photovoltaic conversion. A few LDRDs were terminated early when it appeared clear that the research was not going to succeed. A great many more were successful and led to full Tier 2 LDRDs or direct customer sponsorship. Over a dozen patents are in various stages of prosecution from this work, and one project is being submitted for an R and D 100 award.

  7. LDRD final report on new homogeneous catalysts for direct olefin epoxidation (LDRD 52591).

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, Karen (University of Washington); Smythe, Nicole A. (University of Washington); Moore, Joshua T.; Stewart, Constantine A.; Kemp, Richard Alan; Miller, James Edward; Kornienko, Alexander (New Mexico Institute of Mining and Technology); Denney, Melanie C. (University of Washington); Cetto, Kara L. (University of Washington)

    2006-02-01

    This report summarizes our findings during the study of a novel homogeneous epoxidation catalyst system that uses molecular oxygen as the oxidant, a ''Holy Grail'' in catalysis. While olefins (alkenes) that do not contain allylic hydrogens can be epoxidized directly using heterogeneous catalysts, most olefins cannot, and so a general, atom-efficient route is desired. While most of the work performed on this LDRD has been on pincer complexes of late transition metals, we also scouted out metal/ligand combinations that were significantly different, and unfortunately, less successful. Most of the work reported here deals with phosphorus-ligated Pd hydrides [(PCP)Pd-H]. We have demonstrated that molecular oxygen gas can insert into the Pd-H bond, giving a structurally characterized Pd-OOH species. This species reacts with oxygen acceptors such as olefins to donate an oxygen atom, although in various levels of selectivity, and to generate a [(PCP)Pd-OH] molecule. We discovered that the active [(PCP)Pd-H] active catalyst can be regenerated by addition of either CO or hydrogen. The demonstration of each step of the catalytic cycle is quite significant. Extensions to the pincer-Pd chemistry by attaching a fluorinated tail to the pincer designed to be used in solvents with higher oxygen solubilities are also presented.

  8. Precision formed micro magnets: LDRD project summary report

    Energy Technology Data Exchange (ETDEWEB)

    CHRISTENSON,TODD R.; GARINO,TERRY J.; VENTURINI,EUGENE L.

    2000-02-01

    A microfabrication process is described that provides for the batch realization of miniature rare earth based permanent magnets. Prismatic geometry with features as small as 5 microns, thicknesses up through several hundred microns and with submicron tolerances may be accommodated. The processing is based on a molding technique using deep x-ray lithography as a means to generate high aspect-ratio precision molds from PMMA (poly methyl methacrylate) used as an x-ray photoresist. Subsequent molding of rare-earth permanent magnet (REPM) powder combined with a thermosetting plastic binder may take place directly in the PMMA mold. Further approaches generate an alumina form replicated from the PMMA mold that becomes an intermediate mold for pressing higher density REPM material and allows for higher process temperatures. Maximum energy products of 3--8 MGOe (Mega Gauss Oersted, 1 MGOe = 100/4{pi} kJ/m{sup 3}) are obtained for bonded isotropic forms of REPM with dimensions on the scale of 100 microns and up to 23 MGOe for more dense anisotropic REPM material using higher temperature processing. The utility of miniature precision REPMs is revealed by the demonstration of a miniature multipole brushless DC motor that possesses a pole-anisotropic rotor with dimensions that would otherwise prohibit multipole magnetization using a multipole magnetizing fixture at this scale. Subsequent multipole assembly also leads to miniaturized Halbach arrays, efficient magnetic microactuators, and mechanical spring-like elements which can offset miniaturized mechanical scaling behavior.

  9. Final report for the mobile node authentication LDRD project.

    Energy Technology Data Exchange (ETDEWEB)

    Michalski, John T.; Lanzone, Andrew J.

    2005-09-01

    In hostile ad hoc wireless communication environments, such as battlefield networks, end-node authentication is critical. In a wired infrastructure, this authentication service is typically facilitated by a centrally-located ''authentication certificate generator'' such as a Certificate Authority (CA) server. This centralized approach is ill-suited to meet the needs of mobile ad hoc networks, such as those required by military systems, because of the unpredictable connectivity and dynamic routing. There is a need for a secure and robust approach to mobile node authentication. Current mechanisms either assign a pre-shared key (shared by all participating parties) or require that each node retain a collection of individual keys that are used to communicate with other individual nodes. Both of these approaches have scalability issues and allow a single compromised node to jeopardize the entire mobile node community. In this report, we propose replacing the centralized CA with a distributed CA whose responsibilities are shared between a set of select network nodes. To that end, we develop a protocol that relies on threshold cryptography to perform the fundamental CA duties in a distributed fashion. The protocol is meticulously defined and is implemented it in a series of detailed models. Using these models, mobile wireless scenarios were created on a communication simulator to test the protocol in an operational environment and to gather statistics on its scalability and performance.

  10. Adaption of the Cytokinesis-Block Micronucleus Cytome Assay for Improved Triage Biodosimetry.

    Science.gov (United States)

    Beinke, C; Port, M; Riecke, A; Ruf, C G; Abend, M

    2016-05-01

    The purpose of this work was to adapt a more advanced form of the cytokinesis-block micronucleus (CBMN) cytome assay for triage biodosimetry in the event of a mass casualty radiation incident. We modified scoring procedures for the CBMN cytome assay to optimize field deployability, dose range, accuracy, speed, economy, simplicity and stability. Peripheral blood of 20 donors was irradiated in vitro (0-6 Gy X ray, maximum photon energy 240 keV) and processed for CBMN. Initially, we assessed two manual scoring strategies for accuracy: 1. Conventional scoring, comprised of micronucleus (MN) frequency per 1,000 binucleated (BN) cells (MN/1,000 BN cells); and 2. Evaluation of 1,000, 2,000 and 3,000 cells in total and different cellular subsets based on MN formation and proliferation (e.g., BN cells with and without MN, mononucleated cells). We used linear and logistic regression models to identify the cellular subsets related closest to dose with the best discrimination ability among different doses/dose categories. We validated the most promising subsets and their combinations with 16 blind samples covering a dose range of 0-8.3 Gy. Linear dose-response relationships comparable to the conventional CBMN assay (r(2) = 0.86) were found for BN cells with MN (r(2) = 0.84) and BN cells without MN (r(2) = 0.84). Models of combined cell counts (CCC) of BN cells with and without MN (BN(+MN) and BN(-MN)) with mononucleated cells (Mono) improved this relationship (r(2) = 0.92). Conventional CBMN discriminated dose categories up to 3 Gy with a concordance between 0.96-1.0 upon scoring 1,000 total cells. In 1,000 BN cells, concordances were observed for conventional CBMN up to 4 Gy as well as BN(+MN) or BN(-MN) (about 0.85). At doses of 4-6 Gy, the concordance of conventional CBMN, BN(+MN) and BN(-MN) declined (about 0.55). We found about 20% higher concordance and more precise dose estimates of irradiated and blinded samples for CCC (Mono + BN(+MN)) after scoring 1,000 total cells

  11. Accurate Gene Expression-Based Biodosimetry Using a Minimal Set of Human Gene Transcripts

    Energy Technology Data Exchange (ETDEWEB)

    Tucker, James D., E-mail: jtucker@biology.biosci.wayne.edu [Department of Biological Sciences, Wayne State University, Detroit, Michigan (United States); Joiner, Michael C. [Department of Radiation Oncology, Wayne State University, Detroit, Michigan (United States); Thomas, Robert A.; Grever, William E.; Bakhmutsky, Marina V. [Department of Biological Sciences, Wayne State University, Detroit, Michigan (United States); Chinkhota, Chantelle N.; Smolinski, Joseph M. [Department of Electrical and Computer Engineering, Wayne State University, Detroit, Michigan (United States); Divine, George W. [Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan (United States); Auner, Gregory W. [Department of Electrical and Computer Engineering, Wayne State University, Detroit, Michigan (United States)

    2014-03-15

    Purpose: Rapid and reliable methods for conducting biological dosimetry are a necessity in the event of a large-scale nuclear event. Conventional biodosimetry methods lack the speed, portability, ease of use, and low cost required for triaging numerous victims. Here we address this need by showing that polymerase chain reaction (PCR) on a small number of gene transcripts can provide accurate and rapid dosimetry. The low cost and relative ease of PCR compared with existing dosimetry methods suggest that this approach may be useful in mass-casualty triage situations. Methods and Materials: Human peripheral blood from 60 adult donors was acutely exposed to cobalt-60 gamma rays at doses of 0 (control) to 10 Gy. mRNA expression levels of 121 selected genes were obtained 0.5, 1, and 2 days after exposure by reverse-transcriptase real-time PCR. Optimal dosimetry at each time point was obtained by stepwise regression of dose received against individual gene transcript expression levels. Results: Only 3 to 4 different gene transcripts, ASTN2, CDKN1A, GDF15, and ATM, are needed to explain ≥0.87 of the variance (R{sup 2}). Receiver-operator characteristics, a measure of sensitivity and specificity, of 0.98 for these statistical models were achieved at each time point. Conclusions: The actual and predicted radiation doses agree very closely up to 6 Gy. Dosimetry at 8 and 10 Gy shows some effect of saturation, thereby slightly diminishing the ability to quantify higher exposures. Analyses of these gene transcripts may be advantageous for use in a field-portable device designed to assess exposures in mass casualty situations or in clinical radiation emergencies.

  12. Nanoporous films for epitaxial growth of single crystal semiconductor materials : final LDRD report.

    Energy Technology Data Exchange (ETDEWEB)

    Rowen, Adam M.; Koleske, Daniel David; Fan, Hongyou; Brinker, C. Jeffrey; Burckel, David Bruce; Williams, John Dalton; Arrington, Christian L.; Steen, William Arthur

    2007-10-01

    This senior council Tier 1 LDRD was focused on exploring the use of porous growth masks as a method for defect reduction during heteroepitaxial crystal growth. Initially our goal was to investigate porous silica as a growth mask, however, we expanded the scope of the research to include several other porous growth masks on various size scales, including mesoporous carbon, photolithographically patterned SU-8 and carbonized SU-8 structures. Use of photolithographically defined growth templates represents a new direction, unique in the extensive literature of patterned epitaxial growth, and presents the possibility of providing a single step growth mask. Additional research included investigation of pore viability via electrochemical deposition into high aspect ratio photoresist. This project was a small footprint research effort which, nonetheless, produced significant progress towards both the stated goal as well as unanticipated research directions.

  13. LDRD final report : mesoscale modeling of dynamic loading of heterogeneous materials.

    Energy Technology Data Exchange (ETDEWEB)

    Robbins, Joshua; Dingreville, Remi Philippe Michel; Voth, Thomas Eugene; Furnish, Michael David

    2013-12-01

    Material response to dynamic loading is often dominated by microstructure (grain structure, porosity, inclusions, defects). An example critically important to Sandia's mission is dynamic strength of polycrystalline metals where heterogeneities lead to localization of deformation and loss of shear strength. Microstructural effects are of broad importance to the scientific community and several institutions within DoD and DOE; however, current models rely on inaccurate assumptions about mechanisms at the sub-continuum or mesoscale. Consequently, there is a critical need for accurate and robust methods for modeling heterogeneous material response at this lower length scale. This report summarizes work performed as part of an LDRD effort (FY11 to FY13; project number 151364) to meet these needs.

  14. Final LDRD report : development of advanced UV light emitters and biological agent detection strategies.

    Energy Technology Data Exchange (ETDEWEB)

    Figiel, Jeffrey James; Crawford, Mary Hagerott; Banas, Michael Anthony; Farrow, Darcie; Armstrong, Andrew M.; Serkland, Darwin Keith; Allerman, Andrew Alan; Schmitt, Randal L.

    2007-12-01

    We present the results of a three year LDRD project which has focused on the development of novel, compact, ultraviolet solid-state sources and fluorescence-based sensing platforms that apply such devices to the sensing of biological and nuclear materials. We describe our development of 270-280 nm AlGaN-based semiconductor UV LEDs with performance suitable for evaluation in biosensor platforms as well as our development efforts towards the realization of a 340 nm AlGaN-based laser diode technology. We further review our sensor development efforts, including evaluation of the efficacy of using modulated LED excitation and phase sensitive detection techniques for fluorescence detection of bio molecules and uranyl-containing compounds.

  15. Final LDRD report :ultraviolet water purification systems for rural environments and mobile applications.

    Energy Technology Data Exchange (ETDEWEB)

    Banas, Michael Anthony; Crawford, Mary Hagerott; Ruby, Douglas Scott; Ross, Michael P.; Nelson, Jeffrey Scott; Allerman, Andrew Alan; Boucher, Ray

    2005-11-01

    We present the results of a one year LDRD program that has focused on evaluating the use of newly developed deep ultraviolet LEDs in water purification. We describe our development efforts that have produced an LED-based water exposure set-up and enumerate the advances that have been made in deep UV LED performance throughout the project. The results of E. coli inactivation with 270-295 nm LEDs are presented along with an assessment of the potential for applying deep ultraviolet LED-based water purification to mobile point-of-use applications as well as to rural and international environments where the benefits of photovoltaic-powered systems can be realized.

  16. Assessment of electron beam induced DNA damage in human peripheral blood by alkaline comet assay: a tool for bio-dosimetry

    International Nuclear Information System (INIS)

    lonising radiation is a potent inducer of DNA damage because it causes single and double-strand breaks, alkali-labile sites, base damage and cross-links. Single cell gel electrophoresis (comet assay) provides a very sensitive method for detecting strand breaks and measuring DNA damages in single cells. Biological dosimetry is a necessary complement to physical and clinical dosimetries. Human bio-monitoring studies using the comet assay provide an efficient tool for measuring human exposure to radiation, thus helping in risk assessment and hazard evaluation. Comet assay is a micro-dosimetric technique based on the selection of individual cells in a heterogeneous cell population and is suitable for rapid and sensitive human bio-monitoring. The induction of DNA strand breaks in human peripheral blood after electron irradiation has been investigated using comet assay in alkaline condition. The DNA damages were quantified using different comet parameters such as tail length, percentage tail DNA and olive tail moment (OTM) using the Comet Assay Software Project (CASP). From the study, a dose-dependent increase in DNA damage was observed and the variation follows a linear quadratic model. The variation in OTM with dose after electron irradiation is fitted to, OTMelectron = 1.26 + 1.4 D +0.12 D2 (R2= 0.98) and the result was compared with that of gamma irradiation. From the study, it can be concluded that alkaline Comet Assay can be used as a rapid and sensitive method for radiation bio-dosimetry. It is suitable for human bio-monitoring, especially in cases of incidental exposure to ionising radiation. (author)

  17. LDRD final report on new homogeneous and supported oligomerization catalysts (LDRD 42461).

    Energy Technology Data Exchange (ETDEWEB)

    Hascall, Anthony G.; Kemp, Richard Alan

    2004-11-01

    The overall purpose of this LDRD is multifold. First, we are interested in preparing new homogeneous catalysts that can be used in the oligomerization of ethylene and in understanding commercially important systems better. Second, we are interested in attempting to support these new homogeneous catalysts in the pores of nano- or mesoporous materials in order to force new and unusual distributions of a-olefins to be formed during the oligomerization. Thus the overall purpose is to try to prepare new catalytic species and to possibly control the active site architecture in order to yield certain desired products during a catalytic reaction, much like nature does with enzymes. In order to rationally synthesize catalysts it is imperative to comprehend the function of the various components of the catalyst. In heterogeneous systems, it is of utmost importance to know how a support interacts with the active site of the catalyst. In fact, in the catalysis world this lack of fundamental understanding of the relationship between active site and support is the single largest reason catalysis is considered an 'empirical' or 'black box' science rather than a well-understood one. In this work we will be preparing novel ethylene oligomerization catalysts, which are normally P-O chelated homogeneous complexes, with new ligands that replace P with a stable carbene. We will also examine a commercially catalyst system and investigate the active site in it via X-ray crystallography. We will also attempt to support these materials inside the pores of nano- and mesoporous materials. Essentially, we will be tailoring the size and scale of the catalyst active site and its surrounding environment to match the size of the molecular product(s) we wish to make. The overall purpose of the study will be to prepare new homogeneous catalysts, and if successful in supporting them to examine the effects that steric constraints and pore structures can have on growing oligomer

  18. Examining Radiation-Induced In Vivo and In Vitro Gene Expression Changes of the Peripheral Blood in Different Laboratories for Biodosimetry Purposes: First RENEB Gene Expression Study.

    Science.gov (United States)

    Abend, M; Badie, C; Quintens, R; Kriehuber, R; Manning, G; Macaeva, E; Njima, M; Oskamp, D; Strunz, S; Moertl, S; Doucha-Senf, S; Dahlke, S; Menzel, J; Port, M

    2016-02-01

    The risk of a large-scale event leading to acute radiation exposure necessitates the development of high-throughput methods for providing rapid individual dose estimates. Our work addresses three goals, which align with the directive of the European Union's Realizing the European Network of Biodosimetry project (EU-RENB): 1. To examine the suitability of different gene expression platforms for biodosimetry purposes; 2. To perform this examination using blood samples collected from prostate cancer patients (in vivo) and from healthy donors (in vitro); and 3. To compare radiation-induced gene expression changes of the in vivo with in vitro blood samples. For the in vitro part of this study, EDTA-treated whole blood was irradiated immediately after venipuncture using single X-ray doses (1 Gy/min(-1) dose rate, 100 keV). Blood samples used to generate calibration curves as well as 10 coded (blinded) samples (0-4 Gy dose range) were incubated for 24 h in vitro, lysed and shipped on wet ice. For the in vivo part of the study PAXgene tubes were used and peripheral blood (2.5 ml) was collected from prostate cancer patients before and 24 h after the first fractionated 2 Gy dose of localized radiotherapy to the pelvis [linear accelerator (LINAC), 580 MU/min, exposure 1-1.5 min]. Assays were run in each laboratory according to locally established protocols using either microarray platforms (2 laboratories) or qRT-PCR (2 laboratories). Report times on dose estimates were documented. The mean absolute difference of estimated doses relative to the true doses (Gy) were calculated. Doses were also merged into binary categories reflecting aspects of clinical/diagnostic relevance. For the in vitro part of the study, the earliest report time on dose estimates was 7 h for qRT-PCR and 35 h for microarrays. Methodological variance of gene expression measurements (CV ≤10% for technical replicates) and interindividual variance (≤twofold for all genes) were low. Dose estimates based on

  19. Assessment of the Technologies for Molecular Biodosimetry for Human Low-Dose Radiation Exposure Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Matthew A. Coleman Ph.D.; Narayani Ramakrishnan, Ph.D.; Sally A. Amundson; James D. Tucker, Ph.D.; Stephen D. Dertinger, Ph.D.; Natalia I. Ossetrova, Ph.D.; Tao Chen

    2009-11-16

    -scale changes occur in the gene expression profile involving a broad variety of cell-process pathways after a wide range of both low (<10 cGy) and high dose (>10 cGy) exposures. Evaluation of these potential gene and protein biomarkers for early and late diagnostic information will be critical for determining the efficacy of the signatures to both low and high dose IR exposures. Also needed are approaches that enable rapid handling and processing for mass-casualty and population triage scenarios. Development of in vivo model system will be crucial for validating both the biological and the instrumentation for biodosimetry. Such studies will also help further understanding of the molecular mechanisms of the biological effects of radiation and the differences of responses due to individual genetic variation.

  20. ParaText : scalable solutions for processing and searching very large document collections : final LDRD report.

    Energy Technology Data Exchange (ETDEWEB)

    Crossno, Patricia Joyce; Dunlavy, Daniel M.; Stanton, Eric T.; Shead, Timothy M.

    2010-09-01

    This report is a summary of the accomplishments of the 'Scalable Solutions for Processing and Searching Very Large Document Collections' LDRD, which ran from FY08 through FY10. Our goal was to investigate scalable text analysis; specifically, methods for information retrieval and visualization that could scale to extremely large document collections. Towards that end, we designed, implemented, and demonstrated a scalable framework for text analysis - ParaText - as a major project deliverable. Further, we demonstrated the benefits of using visual analysis in text analysis algorithm development, improved performance of heterogeneous ensemble models in data classification problems, and the advantages of information theoretic methods in user analysis and interpretation in cross language information retrieval. The project involved 5 members of the technical staff and 3 summer interns (including one who worked two summers). It resulted in a total of 14 publications, 3 new software libraries (2 open source and 1 internal to Sandia), several new end-user software applications, and over 20 presentations. Several follow-on projects have already begun or will start in FY11, with additional projects currently in proposal.

  1. Automated visual direction : LDRD 38623 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert J.

    2005-01-01

    Mobile manipulator systems used by emergency response operators consist of an articulated robot arm, a remotely driven base, a collection of cameras, and a remote communications link. Typically the system is completely teleoperated, with the operator using live video feedback to monitor and assess the environment, plan task activities, and to conduct the operations via remote control input devices. The capabilities of these systems are limited, and operators rarely attempt sophisticated operations such as retrieving and utilizing tools, deploying sensors, or building up world models. This project has focused on methods to utilize this video information to enable monitored autonomous behaviors for the mobile manipulator system, with the goal of improving the overall effectiveness of the human/robot system. Work includes visual servoing, visual targeting, utilization of embedded video in 3-D models, and improved methods of camera utilization and calibration.

  2. Covert air vehicle 2003 LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Spletzer, Barry Louis; Callow, Diane Schafer; Salton, Jonathan Robert; Fischer, Gary John

    2003-11-01

    This report describes the technical work carried out under a 2003 Laboratory Directed Research and Development project to develop a covert air vehicle. A mesoscale air vehicle that mimics a bird offers exceptional mobility and the possibility of remaining undetected during flight. Although some such vehicles exist, they are lacking in key areas: unassisted landing and launching, true mimicry of bird flight to remain covert, and a flapping flight time of any real duration. Current mainstream technology does not have the energy or power density necessary to achieve bird like flight for any meaningful length of time; however, Sandia has unique combustion powered linear actuators with the unprecedented high energy and power density needed for bird like flight. The small-scale, high-pressure valves and small-scale ignition to make this work have been developed at Sandia. We will study the feasibility of using this to achieve vehicle takeoff and wing flapping for sustained flight. This type of vehicle has broad applications for reconnaissance and communications networks, and could prove invaluable for military and intelligence operations throughout the world. Initial tests were conducted on scaled versions of the combustion-powered linear actuator. The tests results showed that heat transfer and friction effects dominate the combustion process at 'bird-like' sizes. The problems associated with micro-combustion must be solved before a true bird-like ornithopter can be developed.

  3. Real-time discriminatory sensors for water contamination events :LDRD 52595 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Borek, Theodore Thaddeus III (; ); Carrejo-Simpkins, Kimberly; Wheeler, David Roger; Adkins, Douglas Ray; Robinson, Alex Lockwood; Irwin, Adriane Nadine; Lewis, Patrick Raymond; Goodin, Andrew M.; Shelmidine, Gregory J.; Dirk, Shawn M.; Chambers, William Clayton; Mowry, Curtis Dale (1722 Micro-Total-Analytical Systems); Showalter, Steven Kedrick

    2005-10-01

    The gas-phase {mu}ChemLab{trademark} developed by Sandia can detect volatile organics and semi-volatiles organics via gas phase sampling . The goal of this three year Laboratory Directed Research and Development (LDRD) project was to adapt the components and concepts used by the {mu}ChemLab{trademark} system towards the analysis of water-borne chemicals of current concern. In essence, interfacing the gas-phase {mu}ChemLab{trademark} with water to bring the significant prior investment of Sandia and the advantages of microfabrication and portable analysis to a whole new world of important analytes. These include both chemical weapons agents and their hydrolysis products and disinfection by-products such as Trihalomethanes (THMs) and haloacetic acids (HAAs). THMs and HAAs are currently regulated by EPA due to health issues, yet water utilities do not have rapid on-site methods of detection that would allow them to adjust their processes quickly; protecting consumers, meeting water quality standards, and obeying regulations more easily and with greater confidence. This report documents the results, unique hardware and devices, and methods designed during the project toward the goal stated above. It also presents and discusses the portable field system to measure THMs developed in the course of this project.

  4. Robust Planning for Autonomous Navigation of Mobile Robots in Unstructured, Dynamic Environments: An LDRD Final Report

    Energy Technology Data Exchange (ETDEWEB)

    EISLER, G. RICHARD

    2002-08-01

    This report summarizes the analytical and experimental efforts for the Laboratory Directed Research and Development (LDRD) project entitled ''Robust Planning for Autonomous Navigation of Mobile Robots In Unstructured, Dynamic Environments (AutoNav)''. The project goal was to develop an algorithmic-driven, multi-spectral approach to point-to-point navigation characterized by: segmented on-board trajectory planning, self-contained operation without human support for mission duration, and the development of appropriate sensors and algorithms to navigate unattended. The project was partially successful in achieving gains in sensing, path planning, navigation, and guidance. One of three experimental platforms, the Minimalist Autonomous Testbed, used a repetitive sense-and-re-plan combination to demonstrate the majority of elements necessary for autonomous navigation. However, a critical goal for overall success in arbitrary terrain, that of developing a sensor that is able to distinguish true obstacles that need to be avoided as a function of vehicle scale, still needs substantial research to bring to fruition.

  5. Final Report for the Virtual Reliability Realization System LDRD

    Energy Technology Data Exchange (ETDEWEB)

    DELLIN, THEODORE A.; HENDERSON, CHRISTOPHER L.; O' TOOLE, EDWARD J.

    2000-12-01

    Current approaches to reliability are not adequate to keep pace with the need for faster, better and cheaper products and systems. This is especially true in high consequence of failure applications. The original proposal for the LDRD was to look at this challenge and see if there was a new paradigm that could make reliability predictions, along with a quantitative estimate of the risk in that prediction, in a way that was faster, better and cheaper. Such an approach would be based on the underlying science models that are the backbone of reliability predictions. The new paradigm would be implemented in two software tools: the Virtual Reliability Realization System (VRRS) and the Reliability Expert System (REX). The three-year LDRD was funded at a reduced level for the first year ($120K vs. $250K) and not renewed. Because of the reduced funding, we concentrated on the initial development of the expertise system. We developed an interactive semiconductor calculation tool needed for reliability analyses. We also were able to generate a basic functional system using Microsoft Siteserver Commerce Edition and Microsoft Sequel Server. The base system has the capability to store Office documents from multiple authors, and has the ability to track and charge for usage. The full outline of the knowledge model has been incorporated as well as examples of various types of content.

  6. FY08 LDRD Final Report Regional Climate

    Energy Technology Data Exchange (ETDEWEB)

    Bader, D C; Chin, H; Caldwell, P M

    2009-05-19

    An integrated, multi-model capability for regional climate change simulation is needed to perform original analyses to understand and prepare for the impacts of climate change on the time and space scales that are critical to California's future environmental quality and economic prosperity. Our intent was to develop a very high resolution regional simulation capability to address consequences of climate change in California to complement the global modeling capability that is supported by DOE at LLNL and other institutions to inform national and international energy policies. The California state government, through the California Energy Commission (CEC), institutionalized the State's climate change assessment process through its biennial climate change reports. The bases for these reports, however, are global climate change simulations for future scenarios designed to inform international policy negotiations, and are primarily focused on the global to continental scale impacts of increasing emissions of greenhouse gases. These simulations do not meet the needs of California public and private officials who will make major decisions in the next decade that require an understanding of climate change in California for the next thirty to fifty years and its effects on energy use, water utilization, air quality, agriculture and natural ecosystems. With the additional development of regional dynamical climate modeling capability, LLNL will be able to design and execute global simulations specifically for scenarios important to the state, then use those results to drive regional simulations of the impacts of the simulated climate change for regions as small as individual cities or watersheds. Through this project, we systematically studied the strengths and weaknesses of downscaling global model results with a regional mesoscale model to guide others, particularly university researchers, who are using the technique based on models with less complete

  7. Characterize and Model Final Waste Formulations and Offgas Solids from Thermal Treatment Processes - FY-98 Final Report for LDRD 2349

    Energy Technology Data Exchange (ETDEWEB)

    Kessinger, Glen Frank; Nelson, Lee Orville; Grandy, Jon Drue; Zuck, Larry Douglas; Kong, Peter Chuen Sun; Anderson, Gail

    1999-08-01

    The purpose of LDRD #2349, Characterize and Model Final Waste Formulations and Offgas Solids from Thermal Treatment Processes, was to develop a set of tools that would allow the user to, based on the chemical composition of a waste stream to be immobilized, predict the durability (leach behavior) of the final waste form and the phase assemblages present in the final waste form. The objectives of the project were: • investigation, testing and selection of thermochemical code • development of auxiliary thermochemical database • synthesis of materials for leach testing • collection of leach data • using leach data for leach model development • thermochemical modeling The progress toward completion of these objectives and a discussion of work that needs to be completed to arrive at a logical finishing point for this project will be presented.

  8. Advancements in sensing and perception using structured lighting techniques :an LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Novick, David Keith; Padilla, Denise D.; Davidson, Patrick A. Jr. (.; .); Carlson, Jeffrey J.

    2005-09-01

    This report summarizes the analytical and experimental efforts for the Laboratory Directed Research and Development (LDRD) project entitled ''Advancements in Sensing and Perception using Structured Lighting Techniques''. There is an ever-increasing need for robust, autonomous ground vehicles for counterterrorism and defense missions. Although there has been nearly 30 years of government-sponsored research, it is undisputed that significant advancements in sensing and perception are necessary. We developed an innovative, advanced sensing technology for national security missions serving the Department of Energy, the Department of Defense, and other government agencies. The principal goal of this project was to develop an eye-safe, robust, low-cost, lightweight, 3D structured lighting sensor for use in broad daylight outdoor applications. The market for this technology is wide open due to the unavailability of such a sensor. Currently available laser scanners are slow, bulky and heavy, expensive, fragile, short-range, sensitive to vibration (highly problematic for moving platforms), and unreliable for outdoor use in bright sunlight conditions. Eye-safety issues are a primary concern for currently available laser-based sensors. Passive, stereo-imaging sensors are available for 3D sensing but suffer from several limitations : computationally intensive, require a lighted environment (natural or man-made light source), and don't work for many scenes or regions lacking texture or with ambiguous texture. Our approach leveraged from the advanced capabilities of modern CCD camera technology and Center 6600's expertise in 3D world modeling, mapping, and analysis, using structured lighting. We have a diverse customer base for indoor mapping applications and this research extends our current technology's lifecycle and opens a new market base for outdoor 3D mapping. Applications include precision mapping, autonomous navigation, dexterous

  9. Automated Algorithms for Quantum-Level Accuracy in Atomistic Simulations: LDRD Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Aidan Patrick; Schultz, Peter Andrew; Crozier, Paul; Moore, Stan Gerald; Swiler, Laura Painton; Stephens, John Adam; Trott, Christian Robert; Foiles, Stephen Martin; Tucker, Garritt J. (Drexel University)

    2014-09-01

    This report summarizes the result of LDRD project 12-0395, titled "Automated Algorithms for Quantum-level Accuracy in Atomistic Simulations." During the course of this LDRD, we have developed an interatomic potential for solids and liquids called Spectral Neighbor Analysis Poten- tial (SNAP). The SNAP potential has a very general form and uses machine-learning techniques to reproduce the energies, forces, and stress tensors of a large set of small configurations of atoms, which are obtained using high-accuracy quantum electronic structure (QM) calculations. The local environment of each atom is characterized by a set of bispectrum components of the local neighbor density projected on to a basis of hyperspherical harmonics in four dimensions. The SNAP coef- ficients are determined using weighted least-squares linear regression against the full QM training set. This allows the SNAP potential to be fit in a robust, automated manner to large QM data sets using many bispectrum components. The calculation of the bispectrum components and the SNAP potential are implemented in the LAMMPS parallel molecular dynamics code. Global optimization methods in the DAKOTA software package are used to seek out good choices of hyperparameters that define the overall structure of the SNAP potential. FitSnap.py, a Python-based software pack- age interfacing to both LAMMPS and DAKOTA is used to formulate the linear regression problem, solve it, and analyze the accuracy of the resultant SNAP potential. We describe a SNAP potential for tantalum that accurately reproduces a variety of solid and liquid properties. Most significantly, in contrast to existing tantalum potentials, SNAP correctly predicts the Peierls barrier for screw dislocation motion. We also present results from SNAP potentials generated for indium phosphide (InP) and silica (SiO 2 ). We describe efficient algorithms for calculating SNAP forces and energies in molecular dynamics simulations using massively parallel computers

  10. LDRD final report backside localization of open and shorted IC interconnections LDRD Project (FY98 and FY 99)

    Energy Technology Data Exchange (ETDEWEB)

    Cole, E.I. Jr.; Tangyunyong, P.; Benson, D.A.; Barton, D.L.

    2000-01-01

    Two new failure analysis techniques have been developed for backside and front side localization of open and shorted interconnections on ICs. These scanning optical microscopy techniques take advantage of the interactions between IC defects and localized heating using a focused infrared laser ({lambda} = 1,340 nm). Images are produced by monitoring the voltage changes across a constant current supply used to power the IC as the laser beam is scanned across the sample. The methods utilize the Seebeck Effect to localize open interconnections and Thermally-Induced Voltage Alteration (TIVA) to detect shorts. Initial investigations demonstrated the feasibility of TIVA and Seebeck Effect Imaging (SEI). Subsequent improvements have greatly increased the sensitivity of the TIVA/SEI system, reducing the acquisition times by more than 20X and localizing previously unobserved defects. The interaction physics describing the signal generation process and several examples demonstrating the localization of opens and shorts are described. Operational guidelines and limitations are also discussed. The system improvements, non-linear response of IC defects to heating, modeling of laser heating and examples using the improved system for failure analysis are presented.

  11. Quantitative adaptation analytics for assessing dynamic systems of systems: LDRD Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Gauthier, John H. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). System Readiness & Sustainment Technologies (6133, M/S 1188); Miner, Nadine E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Military & Energy Systems Analysis (6114, M/S 1188); Wilson, Michael L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Resilience and Regulatory Effects (6921, M/S 1138); Le, Hai D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). System Readiness & Sustainment Technologies (6133, M/S 1188); Kao, Gio K. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Networked System Survivability & Assurance (5629, M/S 0671); Melander, Darryl J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Software Systems R& D (9525, M/S 1188); Longsine, Dennis Earl [Sandia National Laboratories, Unknown, Unknown; Vander Meer, Jr., Robert C. [SAIC, Inc., Albuquerque, NM (United States)

    2015-01-01

    Our society is increasingly reliant on systems and interoperating collections of systems, known as systems of systems (SoS). These SoS are often subject to changing missions (e.g., nation- building, arms-control treaties), threats (e.g., asymmetric warfare, terrorism), natural environments (e.g., climate, weather, natural disasters) and budgets. How well can SoS adapt to these types of dynamic conditions? This report details the results of a three year Laboratory Directed Research and Development (LDRD) project aimed at developing metrics and methodologies for quantifying the adaptability of systems and SoS. Work products include: derivation of a set of adaptability metrics, a method for combining the metrics into a system of systems adaptability index (SoSAI) used to compare adaptability of SoS designs, development of a prototype dynamic SoS (proto-dSoS) simulation environment which provides the ability to investigate the validity of the adaptability metric set, and two test cases that evaluate the usefulness of a subset of the adaptability metrics and SoSAI for distinguishing good from poor adaptability in a SoS. Intellectual property results include three patents pending: A Method For Quantifying Relative System Adaptability, Method for Evaluating System Performance, and A Method for Determining Systems Re-Tasking.

  12. Soot formation, transport, and radiation in unsteady diffusion flames : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Suo-Anttila, Jill Marie (Sandia National Laboratories, Albuquerque, NM); Williams, Timothy C.; Shaddix, Christopher R.; Jensen, Kirk A. (Sandia National Laboratories, Albuquerque, NM); Blevins, Linda Gail; Kearney, Sean Patrick (Sandia National Laboratories, Albuquerque, NM); Schefer, Robert W.

    2004-10-01

    Fires pose the dominant risk to the safety and security of nuclear weapons, nuclear transport containers, and DOE and DoD facilities. The thermal hazard from these fires primarily results from radiant emission from high-temperature flame soot. Therefore, it is necessary to understand the local transport and chemical phenomena that determine the distributions of soot concentration, optical properties, and temperature in order to develop and validate constitutive models for large-scale, high-fidelity fire simulations. This report summarizes the findings of a Laboratory Directed Research and Development (LDRD) project devoted to obtaining the critical experimental information needed to develop such constitutive models. A combination of laser diagnostics and extractive measurement techniques have been employed in both steady and pulsed laminar diffusion flames of methane, ethylene, and JP-8 surrogate burning in air. For methane and ethylene, both slot and coannular flame geometries were investigated, as well as normal and inverse diffusion flame geometries. For the JP-8 surrogate, coannular normal diffusion flames were investigated. Soot concentrations, polycyclic aromatic hydrocarbon (PAH) laser-induced fluorescence (LIF) signals, hydroxyl radical (OH) LIF, acetylene and water vapor concentrations, soot zone temperatures, and the velocity field were all successfully measured in both steady and unsteady versions of these various flames. In addition, measurements were made of the soot microstructure, soot dimensionless extinction coefficient (&), and the local radiant heat flux. Taken together, these measurements comprise a unique, extensive database for future development and validation of models of soot formation, transport, and radiation.

  13. Gamma Irradiation Induces DNA Double-Strand Breaks in Fibroblasts: A Model Study for the Development of Biodosimetry

    International Nuclear Information System (INIS)

    Accidental exposure to ionizing radiation can immediately induce double-strand breaks (DSBs) of DNAs which later pose detrimental damage on organisms including genetic instability and cell death. The aim of this study is to simulate such incident by exposing a cell model to gamma radiation and the resulting DNA DSBs were immunofluorescently labeled and quantified to establish a dose response relationship. Human dermal fibroblasts were grown into monolayers before irradiated by gamma rays from a Co-60 source at doses 0, 0.2, 1, 2 and 4 Gy and a dose rate of 0.21 Gy/min. DNA DSBs, which appeared as foci inside the cells' nuclei, were evaluated by flow cytometry and confocal microscopy. Data showed that the foci intensity increased linearly in relation to the increase in irradiation dose within 1 h post exposure. These findings can be further developed to serve as a personal biodosimetry to assess the immediate extent and potential health risks of accidental exposure to ionizing radiation in individuals.

  14. Final LDRD report : development of sample preparation methods for ChIPMA-based imaging mass spectrometry of tissue samples.

    Energy Technology Data Exchange (ETDEWEB)

    Maharrey, Sean P.; Highley, Aaron M.; Behrens, Richard, Jr.; Wiese-Smith, Deneille

    2007-12-01

    The objective of this short-term LDRD project was to acquire the tools needed to use our chemical imaging precision mass analyzer (ChIPMA) instrument to analyze tissue samples. This effort was an outgrowth of discussions with oncologists on the need to find the cellular origin of signals in mass spectra of serum samples, which provide biomarkers for ovarian cancer. The ultimate goal would be to collect chemical images of biopsy samples allowing the chemical images of diseased and nondiseased sections of a sample to be compared. The equipment needed to prepare tissue samples have been acquired and built. This equipment includes an cyro-ultramicrotome for preparing thin sections of samples and a coating unit. The coating unit uses an electrospray system to deposit small droplets of a UV-photo absorbing compound on the surface of the tissue samples. Both units are operational. The tissue sample must be coated with the organic compound to enable matrix assisted laser desorption/ionization (MALDI) and matrix enhanced secondary ion mass spectrometry (ME-SIMS) measurements with the ChIPMA instrument Initial plans to test the sample preparation using human tissue samples required development of administrative procedures beyond the scope of this LDRD. Hence, it was decided to make two types of measurements: (1) Testing the spatial resolution of ME-SIMS by preparing a substrate coated with a mixture of an organic matrix and a bio standard and etching a defined pattern in the coating using a liquid metal ion beam, and (2) preparing and imaging C. elegans worms. Difficulties arose in sectioning the C. elegans for analysis and funds and time to overcome these difficulties were not available in this project. The facilities are now available for preparing biological samples for analysis with the ChIPMA instrument. Some further investment of time and resources in sample preparation should make this a useful tool for chemical imaging applications.

  15. Low-Altitude Airbursts and the Impact Threat - Final LDRD Report.

    Energy Technology Data Exchange (ETDEWEB)

    Boslough, Mark B.; Crawford, David A.

    2007-12-01

    The purpose of this nine-week project was to advance the understanding of low-altitude airbursts by developing the means to model them at extremely high resolution in order to span the scales of entry physics as well as blast wave and plume formation. Small asteroid impacts on Earth are a recognized hazard, but the full nature of the threat is still not well understood. We used shock physics codes to discover emergent phenomena associated with low-altitude airbursts such as the Siberian Tunguska event of 1908 and the Egyptian glass-forming event 29 million years ago. The planetary defense community is beginning to recognize the significant threat from such airbursts. Low-altitude airbursts are the only class of impacts that have a significant probability of occurring within a planning time horizon. There is roughly a 10% chance of a megaton-scale low-altitude airburst event in the next decade.The first part of this LDRD final project report is a preprint of our proceedings paper associated with the plenary presentation at the Hypervelocity Impact Society 2007 Symposium in Williamsburg, Virginia (International Journal of Impact Engineering, in press). The paper summarizes discoveries associated with a series of 2D axially-symmetric CTH simulations. The second part of the report contains slides from an invited presentation at the American Geophysical Union Fall 2007 meeting in San Francisco. The presentation summarizes the results of a series of 3D oblique impact simulations of the 1908 Tunguska explosion. Because of the brevity of this late-start project, the 3D results have not yet been written up for a peer-reviewed publication. We anticipate the opportunity to eventually run simulations that include the actual topography at Tunguska, at which time these results will be published.3

  16. Spatial and temporal resolution of fluid flows: LDRD final report

    Energy Technology Data Exchange (ETDEWEB)

    Tieszen, S.R.; O`Hern, T.J.; Schefer, R.W.; Perea, L.D.

    1998-02-01

    This report describes a Laboratory Directed Research and Development (LDRD) activity to develop a diagnostic technique for simultaneous temporal and spatial resolution of fluid flows. The goal is to obtain two orders of magnitude resolution in two spatial dimensions and time simultaneously. The approach used in this study is to scale up Particle Image Velocimetry (PIV) and Planar Laser Induced Fluorescence (PLIF) to acquire meter-size images at up to 200 frames/sec. Experiments were conducted in buoyant, fully turbulent, non-reacting and reacting plumes with a base diameter of one meter. The PIV results were successful in the ambient gas for all flows, and in the plume for non-reacting helium and reacting methane, but not reacting hydrogen. No PIV was obtained in the hot combustion product region as the seed particles chosen vaporized. Weak signals prevented PLIF in the helium. However, in reacting methane flows, PLIF images speculated to be from Poly-Aromatic-Hydrocarbons were obtained which mark the flame sheets. The results were unexpected and very insightful. A natural fluorescence from the seed particle vapor was also noted in the hydrogen tests.

  17. Chemiresistor microsensors for in-situ monitoring of volatile organic compounds : final LDRD report.

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Michael Loren; Hughes, Robert Clark; Kooser, Ara S.; McGrath, Lucas K.; Ho, Clifford Kuofei; Wright, Jerome L.; Davis, Chad Edward

    2003-09-01

    This report provides a summary of the three-year LDRD (Laboratory Directed Research and Development) project aimed at developing microchemical sensors for continuous, in-situ monitoring of volatile organic compounds. A chemiresistor sensor array was integrated with a unique, waterproof housing that allows the sensors to be operated in a variety of media including air, soil, and water. Numerous tests were performed to evaluate and improve the sensitivity, stability, and discriminatory capabilities of the chemiresistors. Field tests were conducted in California, Nevada, and New Mexico to further test and develop the sensors in actual environments within integrated monitoring systems. The field tests addressed issues regarding data acquisition, telemetry, power requirements, data processing, and other engineering requirements. Significant advances were made in the areas of polymer optimization, packaging, data analysis, discrimination, design, and information dissemination (e.g., real-time web posting of data; see www.sandia.gov/sensor). This project has stimulated significant interest among commercial and academic institutions. A CRADA (Cooperative Research and Development Agreement) was initiated in FY03 to investigate manufacturing methods, and a Work for Others contract was established between Sandia and Edwards Air Force Base for FY02-FY04. Funding was also obtained from DOE as part of their Advanced Monitoring Systems Initiative program from FY01 to FY03, and a DOE EMSP contract was awarded jointly to Sandia and INEEL for FY04-FY06. Contracts were also established for collaborative research with Brigham Young University to further evaluate, understand, and improve the performance of the chemiresistor sensors.

  18. From Idea to Innovation: The Role of LDRD Investments in Sandia's Recent Successful B61 Experiments.

    Energy Technology Data Exchange (ETDEWEB)

    Arrowsmith, Marie Danielle [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-11-01

    The Laboratory Directed Research and Development (LDRD) program, authorized by U.S. Congress in 1991, enables Department of Energy (DOE) laboratories to devote a small portion of their research funding to high-risk and potentially high-payoff research. Because it is high-risk, LDRD-supported research may not lead to immediate mission impacts; however, many successes at DOE labs can be traced back to investments in LDRD. LDRD investments have a history of enabling significant payoffs for long-running DOE and NNSA missions and for providing anticipatory new technologies that ultimately become critical to future missions. Many of Sandia National Laboratories’ successes can be traced back to investments in LDRD. Capabilities from three LDRDs were critical to recent tests of the B61-12 gravity bomb—tests that would previously have only been performed experimentally.

  19. Network discovery, characterization, and prediction : a grand challenge LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Kegelmeyer, W. Philip, Jr.

    2010-11-01

    This report is the final summation of Sandia's Grand Challenge LDRD project No.119351, 'Network Discovery, Characterization and Prediction' (the 'NGC') which ran from FY08 to FY10. The aim of the NGC, in a nutshell, was to research, develop, and evaluate relevant analysis capabilities that address adversarial networks. Unlike some Grand Challenge efforts, that ambition created cultural subgoals, as well as technical and programmatic ones, as the insistence on 'relevancy' required that the Sandia informatics research communities and the analyst user communities come to appreciate each others needs and capabilities in a very deep and concrete way. The NGC generated a number of technical, programmatic, and cultural advances, detailed in this report. There were new algorithmic insights and research that resulted in fifty-three refereed publications and presentations; this report concludes with an abstract-annotated bibliography pointing to them all. The NGC generated three substantial prototypes that not only achieved their intended goals of testing our algorithmic integration, but which also served as vehicles for customer education and program development. The NGC, as intended, has catalyzed future work in this domain; by the end it had already brought in, in new funding, as much funding as had been invested in it. Finally, the NGC knit together previously disparate research staff and user expertise in a fashion that not only addressed our immediate research goals, but which promises to have created an enduring cultural legacy of mutual understanding, in service of Sandia's national security responsibilities in cybersecurity and counter proliferation.

  20. Image processing in biodosimetry: A proposal of a generic free software platform.

    Science.gov (United States)

    Dumpelmann, Matthias; Cadena da Matta, Mariel; Pereira de Lemos Pinto, Marcela Maria; de Salazar E Fernandes, Thiago; Borges da Silva, Edvane; Amaral, Ademir

    2015-08-01

    The scoring of chromosome aberrations is the most reliable biological method for evaluating individual exposure to ionizing radiation. However, microscopic analyses of chromosome human metaphases, generally employed to identify aberrations mainly dicentrics (chromosome with two centromeres), is a laborious task. This method is time consuming and its application in biological dosimetry would be almost impossible in case of a large scale radiation incidents. In this project, a generic software was enhanced for automatic chromosome image processing from a framework originally developed for the Framework V project Simbio, of the European Union for applications in the area of source localization from electroencephalographic signals. The platforms capability is demonstrated by a study comparing automatic segmentation strategies of chromosomes from microscopic images.

  1. Sensor Based Process Control (SBPC) Laboratories Directed Research and Development (LDRD)

    Energy Technology Data Exchange (ETDEWEB)

    Wronosky, J.B.

    1993-03-01

    This report describes the activities and results of an LDRD entitled Sensor Based Process Control. This research examined the needs of the plating industry for monitor and control capabilities with particular emphasis on water effluent from rinse baths. A personal computer-based monitor and control development system was used as a test bed.

  2. High-efficiency high-energy Ka source for the critically-required maximum illumination of x-ray optics on Z using Z-petawatt-driven laser-breakout-afterburner accelerated ultrarelativistic electrons LDRD .

    Energy Technology Data Exchange (ETDEWEB)

    Sefkow, Adam B.; Bennett, Guy R.

    2010-09-01

    Under the auspices of the Science of Extreme Environments LDRD program, a <2 year theoretical- and computational-physics study was performed (LDRD Project 130805) by Guy R Bennett (formally in Center-01600) and Adam B. Sefkow (Center-01600): To investigate novel target designs by which a short-pulse, PW-class beam could create a brighter K{alpha} x-ray source than by simple, direct-laser-irradiation of a flat foil; Direct-Foil-Irradiation (DFI). The computational studies - which are still ongoing at this writing - were performed primarily on the RedStorm supercomputer at Sandia National Laboratories Albuquerque site. The motivation for a higher efficiency K{alpha} emitter was very clear: as the backlighter flux for any x-ray imaging technique on the Z accelerator increases, the signal-to-noise and signal-to-background ratios improve. This ultimately allows the imaging system to reach its full quantitative potential as a diagnostic. Depending on the particular application/experiment this would imply, for example, that the system would have reached its full design spatial resolution and thus the capability to see features that might otherwise be indiscernible with a traditional DFI-like x-ray source. This LDRD began FY09 and ended FY10.

  3. Noncontact surface thermometry for microsystems: LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Abel, Mark (Georgia Institute of Technology, Atlanta, GA); Beecham, Thomas (Georgia Institute of Technology, Atlanta, GA); Graham, Samuel (Georgia Institute of Technology, Atlanta, GA); Kearney, Sean Patrick; Serrano, Justin Raymond; Phinney, Leslie Mary

    2006-10-01

    We describe a Laboratory Directed Research and Development (LDRD) effort to develop and apply laser-based thermometry diagnostics for obtaining spatially resolved temperature maps on working microelectromechanical systems (MEMS). The goal of the effort was to cultivate diagnostic approaches that could adequately resolve the extremely fine MEMS device features, required no modifications to MEMS device design, and which did not perturb the delicate operation of these extremely small devices. Two optical diagnostics were used in this study: microscale Raman spectroscopy and microscale thermoreflectance. Both methods use a low-energy, nonperturbing probe laser beam, whose arbitrary wavelength can be selected for a diffraction-limited focus that meets the need for micron-scale spatial resolution. Raman is exploited most frequently, as this technique provides a simple and unambiguous measure of the absolute device temperature for most any MEMS semiconductor or insulator material under steady state operation. Temperatures are obtained from the spectral position and width of readily isolated peaks in the measured Raman spectra with a maximum uncertainty near {+-}10 K and a spatial resolution of about 1 micron. Application of the Raman technique is demonstrated for V-shaped and flexure-style polycrystalline silicon electrothermal actuators, and for a GaN high-electron-mobility transistor. The potential of the Raman technique for simultaneous measurement of temperature and in-plane stress in silicon MEMS is also demonstrated and future Raman-variant diagnostics for ultra spatio-temporal resolution probing are discussed. Microscale thermoreflectance has been developed as a complement for the primary Raman diagnostic. Thermoreflectance exploits the small-but-measurable temperature dependence of surface optical reflectivity for diagnostic purposes. The temperature-dependent reflectance behavior of bulk silicon, SUMMiT-V polycrystalline silicon films and metal surfaces is

  4. FY07 LDRD Final Report Synthesis under High Pressure and Temperature of New Metal Nitrides

    Energy Technology Data Exchange (ETDEWEB)

    Crowhurst, J C; Sadigh, B; Aberg, D; Zaug, J M; Goncharov, A F

    2008-09-23

    The original aim of this LDRD was to determine with unprecedented precision the melting curve of iron to geophysically relevant pressures. In the course of developing much of the technology and techniques required to obtain this information we have encountered and studied novel chemical reactions some of whose products are stable or metastable under ambient conditions. Specifically we have synthesized nitrides of the platinum group metals including platinum, iridium, and palladium. We have also carried out in depth first principles theoretical investigations into the nature of these materials. We believed that the scientific impact of continuing this work would be greater than that of the original goals of this project. Indeed the work has led to a number of high profile publications with additional publications in preparation. While nitrides of the transition metals are generally of tremendous technological importance, those of the noble metals in particular have enjoyed much experimental and theoretical attention in the very short time since they were first synthesized. The field was and clearly remains open for further study. While the scientific motivation for this research is different from that originally proposed, many of the associated methods in which we have now gained experience are similar or identical. These include use of the diamond anvil cell combined with technologies to generate high temperatures, the in-situ technique of Raman scattering using our purpose-built, state-of-the-art system, analytical techniques for determining the composition of recovered samples such as x-ray photoelectron spectroscopy, and finally synchrotron-based techniques such as x-ray diffraction for structural and equation of state determinations. Close interactions between theorists and experimentalists has and will continue to allow our group to rapidly and reliably interpret complicated results on the structure and dynamics of these compounds and also additional novel

  5. BiodosEPR-2006 Meeting: Acute dosimetry consensus committee recommendations on biodosimetry applications in events involving uses of radiation by terrorists and radiation accidents

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, George A. [U.S. Department of Health and Human Services, Office of Preparedness and Emergency Operations, 200 Independence Avenue, SW, Room 403B-1, Washington, DC 20201 (United States); Swartz, Harold M. [Dept. of Radiology and Physiology Dept., Dartmouth Medical School, HB 7785, Vail 702, Rubin 601, Hanover, NH 03755 (United States); Amundson, Sally A. [Center for Radiological Research, Columbia University Medical Center, 630 W. 168th Street, VC11-215, New York, NY 10032 (United States); Blakely, William F. [Armed Forces Radiobiology Research Inst., 8901 Wisconsin Avenue, Bethesda, MD 20889-5603 (United States)], E-mail: blakely@afrri.usuhs.mil; Buddemeier, Brooke [Science and Technology, U.S. Department of Homeland Security, Washington, DC 20528 (United States); Gallez, Bernard [Biomedical Magnetic Resonance Unit and Lab. of Medicinal Chemistry and Radiopharmacy, Univ. Catholique de Louvain, Brussels (Belgium); Dainiak, Nicholas [Dept. of Medicine, Bridgeport Hospital, 267 Grant Street, Bridgeport, CT 06610 (United States); Goans, Ronald E. [MJW Corporation, 1422 Eagle Bend Drive, Clinton, TN 37716-4029 (United States); Hayes, Robert B. [Remote Sensing Lab., MS RSL-47, P.O. Box 98421, Las Vegas, NV 89193 (United States); Lowry, Patrick C. [Radiation Emergency Assistance Center/Training Site (REAC/TS), Oak Ridge Associated Universities, P.O. Box 117, Oak Ridge, TN 37831-0117 (United States); Noska, Michael A. [Food and Drug Administration, FDA/CDRH, 1350 Piccard Drive, HFZ-240, Rockville, MD 20850 (United States); Okunieff, Paul [Dept. of Radiation Oncology (Box 647), Univ. of Rochester, 601 Elmwood Avenue, Rochester, NY 14642 (United States); Salner, Andrew L. [Helen and Harry Gray Cancer Center, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102 (United States); Schauer, David A. [National Council on Radiation Protection and Measurements, 7910 Woodmont Avenue, Suite 400, Bethesda, MD 20814-3095 (United States)] (and others)

    2007-07-15

    , USA; NCRP, 2005. Key elements of preparing emergency responders for nuclear and radiological terrorism. NCRP Commentary No. 19, Bethesda, Maryland, USA] and international [IAEA, 2005. Generic procedures for medical response during a nuclear or radiological emergency. EPR-Medical 2005, IAEA, Vienna, Austria] agencies have reviewed strategies for acute-phase biodosimetry. Consensus biodosimetric guidelines include: (a) clinical signs and symptoms, including peripheral blood counts, time to onset of nausea and vomiting and presence of impaired cognition and neurological deficits, (b) radioactivity assessment, (c) personal and area dosimetry, (d) cytogenetics, (e) in vivo electron paramagnetic resonance (EPR) and (f) other dosimetry approaches (i.e. blood protein assays, etc.). Emerging biodosimetric technologies may further refine triage and dose assessment strategies. However, guidance is needed regarding which biodosimetry techniques are most useful for different radiological scenarios and consensus protocols must be developed. The Local Organizing Committee for the Second International Conference on Biodosimetry and Seventh International Symposium on EPR Dosimetry and Applications (BiodosEPR-2006 Meeting) convened an Acute Dosimetry Consensus Committee composed of national and international experts to: (a) review the current literature for biodosimetry applications for acute-phase applications in radiological emergencies, (b) describe the strengths and weaknesses of each technique, (c) provide recommendations for the use of biodosimetry assays for selected defined radiation scenarios, and (d) develop protocols to apply these recommended biological dosimetry techniques with currently available supplies and equipment for first responders. The Acute Dosimetry Consensus Committee developed recommendations for use of a prioritized multiple-assay biodosimetric-based strategy, concluding that no single assay is sufficiently robust to address all of the potential radiation

  6. BiodosEPR-2006 Meeting: Acute dosimetry consensus committee recommendations on biodosimetry applications in events involving uses of radiation by terrorists and radiation accidents

    International Nuclear Information System (INIS)

    , USA; NCRP, 2005. Key elements of preparing emergency responders for nuclear and radiological terrorism. NCRP Commentary No. 19, Bethesda, Maryland, USA] and international [IAEA, 2005. Generic procedures for medical response during a nuclear or radiological emergency. EPR-Medical 2005, IAEA, Vienna, Austria] agencies have reviewed strategies for acute-phase biodosimetry. Consensus biodosimetric guidelines include: (a) clinical signs and symptoms, including peripheral blood counts, time to onset of nausea and vomiting and presence of impaired cognition and neurological deficits, (b) radioactivity assessment, (c) personal and area dosimetry, (d) cytogenetics, (e) in vivo electron paramagnetic resonance (EPR) and (f) other dosimetry approaches (i.e. blood protein assays, etc.). Emerging biodosimetric technologies may further refine triage and dose assessment strategies. However, guidance is needed regarding which biodosimetry techniques are most useful for different radiological scenarios and consensus protocols must be developed. The Local Organizing Committee for the Second International Conference on Biodosimetry and Seventh International Symposium on EPR Dosimetry and Applications (BiodosEPR-2006 Meeting) convened an Acute Dosimetry Consensus Committee composed of national and international experts to: (a) review the current literature for biodosimetry applications for acute-phase applications in radiological emergencies, (b) describe the strengths and weaknesses of each technique, (c) provide recommendations for the use of biodosimetry assays for selected defined radiation scenarios, and (d) develop protocols to apply these recommended biological dosimetry techniques with currently available supplies and equipment for first responders. The Acute Dosimetry Consensus Committee developed recommendations for use of a prioritized multiple-assay biodosimetric-based strategy, concluding that no single assay is sufficiently robust to address all of the potential radiation

  7. LDRD final report on massively-parallel linear programming : the parPCx system.

    Energy Technology Data Exchange (ETDEWEB)

    Parekh, Ojas (Emory University, Atlanta, GA); Phillips, Cynthia Ann; Boman, Erik Gunnar

    2005-02-01

    This report summarizes the research and development performed from October 2002 to September 2004 at Sandia National Laboratories under the Laboratory-Directed Research and Development (LDRD) project ''Massively-Parallel Linear Programming''. We developed a linear programming (LP) solver designed to use a large number of processors. LP is the optimization of a linear objective function subject to linear constraints. Companies and universities have expended huge efforts over decades to produce fast, stable serial LP solvers. Previous parallel codes run on shared-memory systems and have little or no distribution of the constraint matrix. We have seen no reports of general LP solver runs on large numbers of processors. Our parallel LP code is based on an efficient serial implementation of Mehrotra's interior-point predictor-corrector algorithm (PCx). The computational core of this algorithm is the assembly and solution of a sparse linear system. We have substantially rewritten the PCx code and based it on Trilinos, the parallel linear algebra library developed at Sandia. Our interior-point method can use either direct or iterative solvers for the linear system. To achieve a good parallel data distribution of the constraint matrix, we use a (pre-release) version of a hypergraph partitioner from the Zoltan partitioning library. We describe the design and implementation of our new LP solver called parPCx and give preliminary computational results. We summarize a number of issues related to efficient parallel solution of LPs with interior-point methods including data distribution, numerical stability, and solving the core linear system using both direct and iterative methods. We describe a number of applications of LP specific to US Department of Energy mission areas and we summarize our efforts to integrate parPCx (and parallel LP solvers in general) into Sandia's massively-parallel integer programming solver PICO (Parallel Interger and

  8. Development of highly integrated magetically and electrostatically actuated micropumps : LDRD 64709 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Sosnowchik, Brian D. (Pennsylvania State University, University Park, PA); Galambos, Paul C.; Hendrix, Jason R. (Florida State University, Tallahassee, FL); Zwolinski, Andrew (Florida State University, Tallahassee, FL)

    2003-12-01

    The pump and actuator systems designed and built in the SUMMiT{trademark} process, Sandia's surface micromachining polysilicon MEMS (Micro-Electro-Mechanical Systems) fabrication technology, on the previous campus executive program LDRD (SAND2002-0704P) with FSU/FAMU (Florida State University/Florida Agricultural and Mechanical University) were characterized in this LDRD. These results demonstrated that the device would pump liquid against the flow resistance of a microfabricated channel, but the devices were determined to be underpowered for reliable pumping. As a result a new set of SUMMiT{trademark} pumps with actuators that generate greater torque will be designed and submitted for fabrication. In this document we will report details of dry actuator/pump assembly testing, wet actuator/pump testing, channel resistance characterization, and new pump/actuator design recommendations.

  9. Final LDRD report : infrared detection and power generation using self-assembled quantum dots.

    Energy Technology Data Exchange (ETDEWEB)

    Cederberg, Jeffrey George; Ellis, Robert; Shaner, Eric Arthur

    2008-02-01

    Alternative solutions are desired for mid-wavelength and long-wavelength infrared radiation detection and imaging arrays. We have investigated quantum dot infrared photodetectors (QDIPs) as a possible solution for long-wavelength infrared (8 to 12 {mu}m) radiation sensing. This document provides a summary for work done under the LDRD 'Infrared Detection and Power Generation Using Self-Assembled Quantum Dots'. Under this LDRD, we have developed QDIP sensors and made efforts to improve these devices. While the sensors fabricated show good responsivity at 80 K, their detectivity is limited by high noise current. Following efforts concentrated on how to reduce or eliminate this problem, but with no clear path was identified to the desired performance improvements.

  10. Exploration of cloud computing late start LDRD #149630 : Raincoat. v. 2.1.

    Energy Technology Data Exchange (ETDEWEB)

    Echeverria, Victor T.; Metral, Michael David; Leger, Michelle A.; Gabert, Kasimir Georg; Edgett, Patrick Garrett; Thai, Tan Q.

    2010-09-01

    This report contains documentation from an interoperability study conducted under the Late Start LDRD 149630, Exploration of Cloud Computing. A small late-start LDRD from last year resulted in a study (Raincoat) on using Virtual Private Networks (VPNs) to enhance security in a hybrid cloud environment. Raincoat initially explored the use of OpenVPN on IPv4 and demonstrates that it is possible to secure the communication channel between two small 'test' clouds (a few nodes each) at New Mexico Tech and Sandia. We extended the Raincoat study to add IPSec support via Vyatta routers, to interface with a public cloud (Amazon Elastic Compute Cloud (EC2)), and to be significantly more scalable than the previous iteration. The study contributed to our understanding of interoperability in a hybrid cloud.

  11. Final LDRD report : science-based solutions to achieve high-performance deep-UV laser diodes.

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Andrew M.; Miller, Mary A.; Crawford, Mary Hagerott; Alessi, Leonard J.; Smith, Michael L.; Henry, Tanya A.; Westlake, Karl R.; Cross, Karen Charlene; Allerman, Andrew Alan; Lee, Stephen Roger

    2011-12-01

    We present the results of a three year LDRD project that has focused on overcoming major materials roadblocks to achieving AlGaN-based deep-UV laser diodes. We describe our growth approach to achieving AlGaN templates with greater than ten times reduction of threading dislocations which resulted in greater than seven times enhancement of AlGaN quantum well photoluminescence and 15 times increase in electroluminescence from LED test structures. We describe the application of deep-level optical spectroscopy to AlGaN epilayers to quantify deep level energies and densities and further correlate defect properties with AlGaN luminescence efficiency. We further review our development of p-type short period superlattice structures as an approach to mitigate the high acceptor activation energies in AlGaN alloys. Finally, we describe our laser diode fabrication process, highlighting the development of highly vertical and smooth etched laser facets, as well as characterization of resulting laser heterostructures.

  12. NATO BIODOSIMETRY STUDY

    Science.gov (United States)

    Badie, C.; Kabacik, S.; Balagurunathan, Y.; Bernard, N.; Brengues, M.; Faggioni, G.; Greither, R.; Lista, F.; Peinnequin, A.; Poyot, T.; Herodin, F.; Missel, A.; Terbrueggen, B.; Zenhausern, F.; Rothkamm, K.; Meineke, V.; Braselmann, H.; Beinke, C.; Abend, M.

    2014-01-01

    The possibility of a large-scale acute radiation exposure necessitates the development of new methods that could provide rapid individual dose estimates with high sample throughput. The focus of the study was an intercomparison of laboratories’ dose-assessment performances using gene expression assays. Lithium-heparinized whole blood from one healthy donor was irradiated (240 kVp, 1 Gy/min) immediately after venipuncture at approximately 37°C using single X-ray doses. Blood samples to establish calibration curves (0.25–4 Gy) as well as 10 blinded test samples (0.1–6.4 Gy) were incubated for 24 h at 37°C supplemented with an equal volume of medium and 10% fetal calf serum. For quantitative reverse transcription polymerase chain reaction (qRT-PCR), samples were lysed, stored at −20°C and shipped on ice. For the Chemical Ligation Dependent Probe Amplification methodology (CLPA), aliquots were incubated in 2 ml CLPA reaction buffer (DxTerity), mixed and shipped at room temperature. Assays were run in each laboratory according to locally established protocols. The mean absolute difference (MAD) of estimated doses relative to the true doses (in Gy) was calculated. We also merged doses into binary categories reflecting aspects of clinical/diagnostic relevance and examined accuracy, sensitivity and specificity. The earliest reported time on dose estimates was <8 h. The standard deviation of technical replicate measurements in 75% of all measurements was below 11%. MAD values of 0.3–0.5 Gy and 0.8–1.3 Gy divided the laboratories contributions into two groups. These fourfold differences in accuracy could be primarily explained by unexpected variances of the housekeeping gene (P =0.0008) and performance differences in processing of calibration and blinded test samples by half of the contributing laboratories. Reported gene expression dose estimates aggregated into binary categories in general showed an accuracies and sensitivities of 93–100% and 76–100% for the groups, with low MAD and high MAD, respectively. In conclusion, gene expression-based dose estimates were reported quickly, and for laboratories with MAD between 0.3–0.5 Gy binary dose categories of clinical significance could be discriminated with an accuracy and sensitivity comparable to established cytogenetic assays. PMID:23886340

  13. Advances in radiation modeling in ALEGRA :a final report for LDRD-67120, efficient implicit mulitgroup radiation calculations.

    Energy Technology Data Exchange (ETDEWEB)

    Mehlhorn, Thomas Alan; Kurecka, Christopher J. (University of Michigan, Ann Arbor, MI); McClarren, Ryan (University of Michigan, Ann Arbor, MI); Brunner, Thomas A.; Holloway, James Paul (University of Michigan, Ann Arbor, MI)

    2005-11-01

    The original LDRD proposal was to use a nonlinear diffusion solver to compute estimates for the material temperature that could then be used in a Implicit Monte Carlo (IMC) calculation. At the end of the first year of the project, it was determined that this was not going to be effective, partially due to the concept, and partially due to the fact that the radiation diffusion package was not as efficient as it could be. The second, and final year, of the project focused on improving the robustness and computational efficiency of the radiation diffusion package in ALEGRA. To this end, several new multigroup diffusion methods have been developed and implemented in ALEGRA. While these methods have been implemented, their effectiveness of reducing overall simulation run time has not been fully tested. Additionally a comprehensive suite of verification problems has been developed for the diffusion package to ensure that it has been implemented correctly. This process took considerable time, but exposed significant bugs in both the previous and new diffusion packages, the linear solve packages, and even the NEVADA Framework's parser. In order to manage this large suite of problem, a new tool called Tampa has been developed. It is a general tool for automating the process of running and analyzing many simulations. Ryan McClarren, at the University of Michigan has been developing a Spherical Harmonics capability for unstructured meshes. While still in the early phases of development, this promises to bridge the gap in accuracy between a full transport solution using IMC and the diffusion approximation.

  14. FY04 LDRD Final Report Stroke Sensor Development Using Microdot Sensor Arrays

    Energy Technology Data Exchange (ETDEWEB)

    Carter, J C; Wilson, T S; Alvis, R M; Paulson, C N; Setlur, U S; McBride, M T; Brown, S B; Bearinger, J P; Colston, B W

    2005-11-15

    major thrust area for the Medical Technology Program (M-division). Through MTP, LLNL has a sizable investment and recognizable expertise in stroke treatment research. The proposed microdot array sensor for stroke will complement this existing program in which mechanical devices are being designed for removing the thrombus. The following list of stroke projects and their relative status shows that MTP has a proven track record of taking ideas to industry: The goal of this LDRD funded project was to develop and demonstrate a minimally invasive optical fiber-based sensor for rapid and in-vivo measurements of multiple stroke biomarkers (e.g. pH and enzyme). The development of this sensor also required the development of a new fabrication technology for attaching indicator chemistries to optical fibers. A benefit of this work is to provide clinicians with a tool to assess vascular integrity of the region beyond the thrombus to determine whether or not it is safe to proceed with the removal of the clot. Such an assessment could extend the use of thrombolytic drug treatment to acute stroke victims outside the current rigid temporal limitation of 3 hours. Furthermore, this sensor would also provide a tool for use with emerging treatments involving the use of mechanical devices for removing the thrombus. The sensor effectively assesses the risk for reperfusion injury.

  15. Behavior-aware decision support systems : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, Gary B.; Homer, Jack (Homer Consulting); Chenoweth, Brooke N.; Backus, George A.; Strip, David R.

    2007-11-01

    As Sandia National Laboratories serves its mission to provide support for the security-related interests of the United States, it is faced with considering the behavioral responses that drive problems, mitigate interventions, or lead to unintended consequences. The effort described here expands earlier works in using healthcare simulation to develop behavior-aware decision support systems. This report focuses on using qualitative choice techniques and enhancing two analysis models developed in a sister project.

  16. FY05 LDRD Final Report, A Revolution in Biological Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, H N; Bajt, S; Balhorn, R; Barty, A; Barsky, D; Bogan, M; Chung, S; Frank, M; Hau-Riege, S; Ishii, H; London, R; Marchesini, S; Noy, A; Segelke, B; Szoke, A; Szoke, H; Trebes, J; Wootton, A; Hajdu, J; Bergh, M; Caleman, C; Huldt, G; Lejon, S; der Spoel, D v; Howells, M; He, H; Spence, J; Nugent, K; Ingerman, E

    2006-01-20

    X-ray free-electron lasers (XFELs) are currently under development and will provide a peak brightness more than 10 orders of magnitude higher than modern synchrotrons. The goal of this project was to perform the fundamental research to evaluate the possibility of harnessing these unique x-ray sources to image single biological particles and molecules at atomic resolution. Using a combination of computational modeling and experimental verification where possible, they showed that it should indeed be possible to record coherent scattering patterns from single molecules with pulses that are shorter than the timescales for the degradation of the structure due to the interaction with those pulses. They used these models to determine the effectiveness of strategies to allow imaging using longer XFEL pulses and to design validation experiments to be carried out at interim ultrafast sources. They also developed and demonstrated methods to recover three-dimensional (3D) images from coherent diffraction patterns, similar to those expected from XFELs. The images of micron-sized test objects are the highest-resolution 3D images of any noncrystalline material ever formed with x-rays. The project resulted in 14 publications in peer-reviewed journals and four records of invention.

  17. Autonomous intelligent assembly systems LDRD 105746 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert J.

    2013-04-01

    This report documents a three-year to develop technology that enables mobile robots to perform autonomous assembly tasks in unstructured outdoor environments. This is a multi-tier problem that requires an integration of a large number of different software technologies including: command and control, estimation and localization, distributed communications, object recognition, pose estimation, real-time scanning, and scene interpretation. Although ultimately unsuccessful in achieving a target brick stacking task autonomously, numerous important component technologies were nevertheless developed. Such technologies include: a patent-pending polygon snake algorithm for robust feature tracking, a color grid algorithm for uniquely identification and calibration, a command and control framework for abstracting robot commands, a scanning capability that utilizes a compact robot portable scanner, and more. This report describes this project and these developed technologies.

  18. Final report LDRD project 105816 : model reduction of large dynamic systems with localized nonlinearities.

    Energy Technology Data Exchange (ETDEWEB)

    Lehoucq, Richard B.; Segalman, Daniel Joseph; Hetmaniuk, Ulrich L. (University of Washington, Seattle, WA); Dohrmann, Clark R.

    2009-10-01

    Advanced computing hardware and software written to exploit massively parallel architectures greatly facilitate the computation of extremely large problems. On the other hand, these tools, though enabling higher fidelity models, have often resulted in much longer run-times and turn-around-times in providing answers to engineering problems. The impediments include smaller elements and consequently smaller time steps, much larger systems of equations to solve, and the inclusion of nonlinearities that had been ignored in days when lower fidelity models were the norm. The research effort reported focuses on the accelerating the analysis process for structural dynamics though combinations of model reduction and mitigation of some factors that lead to over-meshing.

  19. Molecular dynamics of gases and vapors in nanoporous solids. Final LDRD project report

    Energy Technology Data Exchange (ETDEWEB)

    Pohl, P.I.

    1996-08-01

    This report provides a study of gases in microporous solids using molecular modeling. The theory of gas transport in porous materials as well as the molecular modeling literature is briefly reviewed. Work complete is described and analyzed with retard to the prevailing theory. The work covers two simple subjects, construction of porous solid models and diffusion of He, H{sub 2}, Ar and CH{sub 4} down a pressure gradient across the material models as in typical membrane permeation experiments. The broader objective is to enhance our capability to efficiently and accurately develop, produce and apply microporous materials.

  20. Final report for the Multiprotocol Label Switching (MPLS) control plane security LDRD project.

    Energy Technology Data Exchange (ETDEWEB)

    Torgerson, Mark Dolan; Michalski, John T.; Tarman, Thomas David; Black, Stephen P.; Pierson, Lyndon George

    2003-09-01

    As rapid Internet growth continues, global communications becomes more dependent on Internet availability for information transfer. Recently, the Internet Engineering Task Force (IETF) introduced a new protocol, Multiple Protocol Label Switching (MPLS), to provide high-performance data flows within the Internet. MPLS emulates two major aspects of the Asynchronous Transfer Mode (ATM) technology. First, each initial IP packet is 'routed' to its destination based on previously known delay and congestion avoidance mechanisms. This allows for effective distribution of network resources and reduces the probability of congestion. Second, after route selection each subsequent packet is assigned a label at each hop, which determines the output port for the packet to reach its final destination. These labels guide the forwarding of each packet at routing nodes more efficiently and with more control than traditional IP forwarding (based on complete address information in each packet) for high-performance data flows. Label assignment is critical in the prompt and accurate delivery of user data. However, the protocols for label distribution were not adequately secured. Thus, if an adversary compromises a node by intercepting and modifying, or more simply injecting false labels into the packet-forwarding engine, the propagation of improperly labeled data flows could create instability in the entire network. In addition, some Virtual Private Network (VPN) solutions take advantage of this 'virtual channel' configuration to eliminate the need for user data encryption to provide privacy. VPN's relying on MPLS require accurate label assignment to maintain user data protection. This research developed a working distributive trust model that demonstrated how to deploy confidentiality, authentication, and non-repudiation in the global network label switching control plane. Simulation models and laboratory testbed implementations that demonstrated this concept were developed, and results from this research were transferred to industry via standards in the Optical Internetworking Forum (OIF).

  1. Final report : LDRD project 79824 carbon nanotube sorting via DNA-directed self-assembly.

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, David B; Leung, Kevin; Rempe, Susan B.; Dossa, Paul D.; Frischknecht, Amalie Lucile; Martin, Marcus Gary

    2007-10-01

    Single-wall carbon nanotubes (SWNTs) have shown great promise in novel applications in molecular electronics, biohazard detection, and composite materials. Commercially synthesized nanotubes exhibit a wide dispersion of geometries and conductivities, and tend to aggregate. Hence the key to using these materials is the ability to solubilize and sort carbon nanotubes according to their geometric/electronic properties. One of the most effective dispersants is single-stranded DNA (ssDNA), but there are many outstanding questions regarding the interaction between nucleic acids and SWNTs. In this work we focus on the interactions of SWNTs with single monomers of nucleic acids, as a first step to answering these outstanding questions. We use atomistic molecular dynamics simulations to calculate the binding energy of six different nucleotide monophosphates (NMPs) to a (6,0) single-wall carbon nanotube in aqueous solution. We find that the binding energies are generally favorable, of the order of a few kcal/mol. The binding energies of the different NMPs were very similar in salt solution, whereas we found a range of binding energies for NMPs in pure water. The binding energies are sensitive to the details of the association of the sodium ions with the phosphate groups and also to the average conformations of the nucleotides. We use electronic structure (Density Functional Theory (DFT) and Moller-Plesset second order perturbation to uncorrelated Hartree Fock theory (MP2)) methods to complement the classical force field study. With judicious choices of DFT exchange correlation functionals, we find that DFT, MP2, and classical force field predictions are in qualitative and even quantitative agreement; all three methods should give reliable and valid predictions. However, in one important case, the interactions between ions and metallic carbon nanotubes--the SWNT polarization-induced affinity for ions, neglected in most classical force field studies, is found to be extremely large (on the order of electron volts) and may have important consequences for various SWNT applications. Finally, the adsorption of NMPs onto single-walled carbon nanotubes were studied experimentally. The nanotubes were sonicated in the presence of the nucleotides at various weight fractions and centrifuged before examining the ultraviolet absorbance of the resulting supernatant. A distinct Langmuir adsorption isotherm was obtained for each nucleotide. All of the nucleotides differ in their saturation value as well as their initial slope, which we attribute to differences both in nucleotide structure and in the binding ability of different types or clusters of tubes. Results from this simple system provide insights toward development of dispersion and separation methods for nanotubes: strongly binding nucleotides are likely to help disperse, whereas weaker ones may provide selectivity that may be beneficial to a separation process.

  2. Final report for LDRD Project 93633 : new hash function for data protection.

    Energy Technology Data Exchange (ETDEWEB)

    Draelos, Timothy John; Dautenhahn, Nathan; Schroeppel, Richard Crabtree; Tolk, Keith Michael; Orman, Hilarie (PurpleStreak, Inc.); Walker, Andrea Mae; Malone, Sean; Lee, Eric; Neumann, William Douglas; Cordwell, William R.; Torgerson, Mark Dolan; Anderson, Eric; Lanzone, Andrew J.; Collins, Michael Joseph; McDonald, Timothy Scott; Caskey, Susan Adele

    2009-03-01

    The security of the widely-used cryptographic hash function SHA1 has been impugned. We have developed two replacement hash functions. The first, SHA1X, is a drop-in replacement for SHA1. The second, SANDstorm, has been submitted as a candidate to the NIST-sponsored SHA3 Hash Function competition.

  3. Two dimensional point of use fuel cell : a final LDRD project report.

    Energy Technology Data Exchange (ETDEWEB)

    Zavadil, Kevin Robert; Hickner, Michael A. (Pennsylvania State University, University Park, PA); Gross, Matthew L. (Pennsylvania State University, University Park, PA)

    2011-03-01

    The Proliferation Assessment (program area - Things Thin) within the Defense Systems and Assessment Investment Area desires high energy density and long-lived power sources with moderate currents (mA) that can be used as building blocks in platforms for the continuous monitoring of chemical, biological, and radiological agents. Fuel cells can be an optimum choice for a power source because of the high energy densities that are possible with liquid fuels. Additionally, power generation and fuel storage can be decoupled in a fuel cell for independent control of energy and power density for customized, application-driven power solutions. Direct methanol fuel cells (DMFC) are explored as a possible concept to develop into ultrathin or two-dimensional power sources. New developments in nanotechnology, advanced fabrication techniques, and materials science are exploited to create a planar DMFC that could be co-located with electronics in a chip format. Carbon nanotubes and pyrolyzed polymers are used as building block electrodes - porous, mechanically compliant current collectors. Directed assembly methods including surface functionalization and layer-by-layer deposition with polyelectrolytes are used to pattern, build, and add functionality to these electrodes. These same techniques are used to incorporate nanoscale selective electrocatalyst into the carbon electrodes to provide a high density of active electron transfer sites for the methanol oxidation and oxygen reduction reactions. The resulting electrodes are characterized in terms of their physical properties, electrocatalytic function, and selectivity to better understand how processing impacts their performance attributes. The basic function of a membrane electrode assembly is demonstrated for several prototype devices.

  4. Final report on LDRD project : narrow-linewidth VCSELs for atomic microsystems.

    Energy Technology Data Exchange (ETDEWEB)

    Chow, Weng Wah; Geib, Kent Martin; Peake, Gregory Merwin; Serkland, Darwin Keith

    2011-09-01

    Vertical-cavity surface-emitting lasers (VCSELs) are well suited for emerging photonic microsystems due to their low power consumption, ease of integration with other optical components, and single frequency operation. However, the typical VCSEL linewidth of 100 MHz is approximately ten times wider than the natural linewidth of atoms used in atomic beam clocks and trapped atom research, which degrades or completely destroys performance in those systems. This report documents our efforts to reduce VCSEL linewidths below 10 MHz to meet the needs of advanced sub-Doppler atomic microsystems, such as cold-atom traps. We have investigated two complementary approaches to reduce VCSEL linewidth: (A) increasing the laser-cavity quality factor, and (B) decreasing the linewidth enhancement factor (alpha) of the optical gain medium. We have developed two new VCSEL devices that achieved increased cavity quality factors: (1) all-semiconductor extended-cavity VCSELs, and (2) micro-external-cavity surface-emitting lasers (MECSELs). These new VCSEL devices have demonstrated linewidths below 10 MHz, and linewidths below 1 MHz seem feasible with further optimization.

  5. FY07 LDRD Final Report Neutron Capture Cross-Section Measurements at DANCE

    Energy Technology Data Exchange (ETDEWEB)

    Parker, W; Agvaanluvsan, U; Wilk, P; Becker, J; Wang, T

    2008-02-08

    We have measured neutron capture cross sections intended to address defense science problems including mix and the Quantification of Margins and Uncertainties (QMU), and provide details about statistical decay of excited nuclei. A major part of this project included developing the ability to produce radioactive targets. The cross-section measurements were made using the white neutron source at the Los Alamos Neutron Science Center, the detector array called DANCE (The Detector for Advanced Neutron Capture Experiments) and targets important for astrophysics and stockpile stewardship. DANCE is at the leading edge of neutron capture physics and represents a major leap forward in capability. The detector array was recently built with LDRD money. Our measurements are a significant part of the early results from the new experimental DANCE facility. Neutron capture reactions are important for basic nuclear science, including astrophysics and the statistics of the {gamma}-ray cascades, and for applied science, including stockpile science and technology. We were most interested in neutron capture with neutron energies in the range between 1 eV and a few hundred keV, with targets important to basic science, and the s-process in particular. Of particular interest were neutron capture cross-section measurements of rare isotopes, especially radioactive isotopes. A strong collaboration between universities and Los Alamos due to the Academic Alliance was in place at the start of our project. Our project gave Livermore leverage in focusing on Livermore interests. The Lawrence Livermore Laboratory did not have a resident expert in cross-section measurements; this project allowed us to develop this expertise. For many radionuclides, the cross sections for destruction, especially (n,{gamma}), are not well known, and there is no adequate model that describes neutron capture. The modeling problem is significant because, at low energies where capture reactions are important, the neutron

  6. FY07 LDRD Final Report Neutron Capture Cross-Section Measurements at DANCE

    International Nuclear Information System (INIS)

    We have measured neutron capture cross sections intended to address defense science problems including mix and the Quantification of Margins and Uncertainties (QMU), and provide details about statistical decay of excited nuclei. A major part of this project included developing the ability to produce radioactive targets. The cross-section measurements were made using the white neutron source at the Los Alamos Neutron Science Center, the detector array called DANCE (The Detector for Advanced Neutron Capture Experiments) and targets important for astrophysics and stockpile stewardship. DANCE is at the leading edge of neutron capture physics and represents a major leap forward in capability. The detector array was recently built with LDRD money. Our measurements are a significant part of the early results from the new experimental DANCE facility. Neutron capture reactions are important for basic nuclear science, including astrophysics and the statistics of the γ-ray cascades, and for applied science, including stockpile science and technology. We were most interested in neutron capture with neutron energies in the range between 1 eV and a few hundred keV, with targets important to basic science, and the s-process in particular. Of particular interest were neutron capture cross-section measurements of rare isotopes, especially radioactive isotopes. A strong collaboration between universities and Los Alamos due to the Academic Alliance was in place at the start of our project. Our project gave Livermore leverage in focusing on Livermore interests. The Lawrence Livermore Laboratory did not have a resident expert in cross-section measurements; this project allowed us to develop this expertise. For many radionuclides, the cross sections for destruction, especially (n,γ), are not well known, and there is no adequate model that describes neutron capture. The modeling problem is significant because, at low energies where capture reactions are important, the neutron reaction

  7. Enhanced Vapor-Phase Diffusion in Porous Media - LDRD Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Ho, C.K.; Webb, S.W.

    1999-01-01

    As part of the Laboratory-Directed Research and Development (LDRD) Program at Sandia National Laboratories, an investigation into the existence of enhanced vapor-phase diffusion (EVD) in porous media has been conducted. A thorough literature review was initially performed across multiple disciplines (soil science and engineering), and based on this review, the existence of EVD was found to be questionable. As a result, modeling and experiments were initiated to investigate the existence of EVD. In this LDRD, the first mechanistic model of EVD was developed which demonstrated the mechanisms responsible for EVD. The first direct measurements of EVD have also been conducted at multiple scales. Measurements have been made at the pore scale, in a two- dimensional network as represented by a fracture aperture, and in a porous medium. Significant enhancement of vapor-phase transport relative to Fickian diffusion was measured in all cases. The modeling and experimental results provide additional mechanisms for EVD beyond those presented by the generally accepted model of Philip and deVries (1957), which required a thermal gradient for EVD to exist. Modeling and experimental results show significant enhancement under isothermal conditions. Application of EVD to vapor transport in the near-surface vadose zone show a significant variation between no enhancement, the model of Philip and deVries, and the present results. Based on this information, the model of Philip and deVries may need to be modified, and additional studies are recommended.

  8. Development of efficient, integrated cellulosic biorefineries : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Teh, Kwee-Yan; Hecht, Ethan S.; Shaddix, Christopher R.; Buffleben, George M.; Dibble, Dean C.; Lutz, Andrew E.

    2010-09-01

    Cellulosic ethanol, generated from lignocellulosic biomass sources such as grasses and trees, is a promising alternative to conventional starch- and sugar-based ethanol production in terms of potential production quantities, CO{sub 2} impact, and economic competitiveness. In addition, cellulosic ethanol can be generated (at least in principle) without competing with food production. However, approximately 1/3 of the lignocellulosic biomass material (including all of the lignin) cannot be converted to ethanol through biochemical means and must be extracted at some point in the biochemical process. In this project we gathered basic information on the prospects for utilizing this lignin residue material in thermochemical conversion processes to improve the overall energy efficiency or liquid fuel production capacity of cellulosic biorefineries. Two existing pretreatment approaches, soaking in aqueous ammonia (SAA) and the Arkenol (strong sulfuric acid) process, were implemented at Sandia and used to generated suitable quantities of residue material from corn stover and eucalyptus feedstocks for subsequent thermochemical research. A third, novel technique, using ionic liquids (IL) was investigated by Sandia researchers at the Joint Bioenergy Institute (JBEI), but was not successful in isolating sufficient lignin residue. Additional residue material for thermochemical research was supplied from the dilute-acid simultaneous saccharification/fermentation (SSF) pilot-scale process at the National Renewable Energy Laboratory (NREL). The high-temperature volatiles yields of the different residues were measured, as were the char combustion reactivities. The residue chars showed slightly lower reactivity than raw biomass char, except for the SSF residue, which had substantially lower reactivity. Exergy analysis was applied to the NREL standard process design model for thermochemical ethanol production and from a prototypical dedicated biochemical process, with process data

  9. Gamma-H2AX biodosimetry for use in large scale radiation incidents: comparison of a rapid ‘96 well lyse/fix’ protocol with a routine method

    Directory of Open Access Journals (Sweden)

    Jayne Moquet

    2014-03-01

    Full Text Available Following a radiation incident, preliminary dose estimates made by γ-H2AX foci analysis can supplement the early triage of casualties based on clinical symptoms. Sample processing time is important when many individuals need to be rapidly assessed. A protocol was therefore developed for high sample throughput that requires less than 0.1 ml blood, thus potentially enabling finger prick sampling. The technique combines red blood cell lysis and leukocyte fixation in one step on a 96 well plate, in contrast to the routine protocol, where lymphocytes in larger blood volumes are typically separated by Ficoll density gradient centrifugation with subsequent washing and fixation steps. The rapid ‘96 well lyse/fix’ method reduced the estimated sample processing time for 96 samples to about 4 h compared to 15 h using the routine protocol. However, scoring 20 cells in 96 samples prepared by the rapid protocol took longer than for the routine method (3.1 versus 1.5 h at zero dose; 7.0 versus 6.1 h for irradiated samples. Similar foci yields were scored for both protocols and consistent dose estimates were obtained for samples exposed to 0, 0.2, 0.6, 1.1, 1.2, 2.1 and 4.3 Gy of 250 kVp X-rays at 0.5 Gy/min and incubated for 2 h. Linear regression coefficients were 0.87 ± 0.06 (R2 = 97.6% and 0.85 ± 0.05 (R2 = 98.3% for estimated versus actual doses for the routine and lyse/fix method, respectively. The lyse/fix protocol can therefore facilitate high throughput processing for γ-H2AX biodosimetry for use in large scale radiation incidents, at the cost of somewhat longer foci scoring times.

  10. Bioagent detection using miniaturized NMR and nanoparticle amplification : final LDRD report.

    Energy Technology Data Exchange (ETDEWEB)

    Clewett, C. F. M.; Adams, David Price; Fan, Hongyou; Williams, John D.; Sillerud, Laurel O.; Alam, Todd Michael; Aldophi, Natalie L. (New Mexico Resonance, Albuquerque, NM); McDowell, Andrew F. (New Mexico Resonance, Albuquerque, NM)

    2006-11-01

    This LDRD program was directed towards the development of a portable micro-nuclear magnetic resonance ({micro}-NMR) spectrometer for the detection of bioagents via induced amplification of solvent relaxation based on superparamagnetic nanoparticles. The first component of this research was the fabrication and testing of two different micro-coil ({micro}-coil) platforms: namely a planar spiral NMR {micro}-coil and a cylindrical solenoid NMR {micro}-coil. These fabrication techniques are described along with the testing of the NMR performance for the individual coils. The NMR relaxivity for a series of water soluble FeMn oxide nanoparticles was also determined to explore the influence of the nanoparticle size on the observed NMR relaxation properties. In addition, The use of commercially produced superparamagnetic iron oxide nanoparticles (SPIONs) for amplification via NMR based relaxation mechanisms was also demonstrated, with the lower detection limit in number of SPIONs per nanoliter (nL) being determined.

  11. Transmissive infrared frequency selective surfaces and infrared antennas : final report for LDRD 105749.

    Energy Technology Data Exchange (ETDEWEB)

    Wendt, Joel Robert; Hadley, G. Ronald; Samora, Sally; Loui, Hung; Cruz-Cabrera, Alvaro Augusto; Davids, Paul; Kemme, Shanalyn A.; Basilio, Lorena I.; Johnson, William Arthur; Peters, David William

    2009-09-01

    Plasmonic structures open up new opportunities in photonic devices, sometimes offering an alternate method to perform a function and sometimes offering capabilities not possible with standard optics. In this LDRD we successfully demonstrated metal coatings on optical surfaces that do not adversely affect the transmission of those surfaces at the design frequency. This technology could be applied as an RF noise blocking layer across an optical aperture or as a method to apply an electric field to an active electro-optic device without affecting optical performance. We also demonstrated thin optical absorbers using similar patterned surfaces. These infrared optical antennas show promise as a method to improve performance in mercury cadmium telluride detectors. Furthermore, these structures could be coupled with other components to lead to direct rectification of infrared radiation. This possibility leads to a new method for infrared detection and energy harvesting of infrared radiation.

  12. Quantum Cascade Lasers (QCLs) for standoff explosives detection : LDRD 138733 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Theisen, Lisa Anne; Linker, Kevin Lane

    2009-09-01

    Continued acts of terrorism using explosive materials throughout the world have led to great interest in explosives detection technology, especially technologies that have a potential for remote or standoff detection. This LDRD was undertaken to investigate the benefit of the possible use of quantum cascade lasers (QCLs) in standoff explosives detection equipment. Standoff detection of explosives is currently one of the most difficult problems facing the explosives detection community. Increased domestic and troop security could be achieved through the remote detection of explosives. An effective remote or standoff explosives detection capability would save lives and prevent losses of mission-critical resources by increasing the distance between the explosives and the intended targets and/or security forces. Many sectors of the US government are urgently attempting to obtain useful equipment to deploy to our troops currently serving in hostile environments. This LDRD was undertaken to investigate the potential benefits of utilizing quantum cascade lasers (QCLs) in standoff detection systems. This report documents the potential opportunities that Sandia National Laboratories can contribute to the field of QCL development. The following is a list of areas where SNL can contribute: (1) Determine optimal wavelengths for standoff explosives detection utilizing QCLs; (2) Optimize the photon collection and detection efficiency of a detection system for optical spectroscopy; (3) Develop QCLs with broader wavelength tunability (current technology is a 10% change in wavelength) while maintaining high efficiency; (4) Perform system engineering in the design of a complete detection system and not just the laser head; and (5) Perform real-world testing with explosive materials with commercial prototype detection systems.

  13. Filtered Rayleigh scattering diagnostic for multi-parameter thermal-fluids measurements : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Beresh, Steven Jay; Grasser, Thomas W.; Kearney, Sean Patrick; Schefer, Robert W.

    2004-01-01

    Simulation-based life-cycle-engineering and the ASCI program have resulted in models of unprecedented size and fidelity. The validation of these models requires high-resolution, multi-parameter diagnostics. Within the thermal-fluids disciplines, the need for detailed, high-fidelity measurements exceeds the limits of current engineering sciences capabilities and severely tests the state of the art. The focus of this LDRD is the development and application of filtered Rayleigh scattering (FRS) for high-resolution, nonintrusive measurement of gas-phase velocity and temperature. With FRS, the flow is laser-illuminated and Rayleigh scattering from naturally occurring sources is detected through a molecular filter. The filtered transmission may be interpreted to yield point or planar measurements of three-component velocities and/or thermodynamic state. Different experimental configurations may be employed to obtain compromises between spatial resolution, time resolution, and the quantity of simultaneously measured flow variables. In this report, we present the results of a three-year LDRD-funded effort to develop FRS combustion thermometry and Aerosciences velocity measurement systems. The working principles and details of our FRS opto-electronic system are presented in detail. For combustion thermometry we present 2-D, spatially correlated FRS results from nonsooting premixed and diffusion flames and from a sooting premixed flame. The FRS-measured temperatures are accurate to within {+-}50 K (3%) in a premixed CH4-air flame and within {+-}100 K for a vortex-strained diluted CH4-air diffusion flame where the FRS technique is severely tested by large variation in scattering cross section. In the diffusion flame work, FRS has been combined with Raman imaging of the CH4 fuel molecule to correct for the local light scattering properties of the combustion gases. To our knowledge, this is the first extension of FRS to nonpremixed combustion and the first use of joint FRS

  14. Use of electron paramagnetic resonance dosimetry with tooth enamel for retrospective dose assessment. Report of a co-ordinated research project

    International Nuclear Information System (INIS)

    Electron paramagnetic resonance (EPR) dosimetry is a physical method for the assessment of absorbed dose from ionising radiation. It is based on the measurement of stable radiation induced radicals in human calcified tissues (primarily in tooth enamel). EPR dosimetry with teeth is now firmly established in retrospective dosimetry. It is a powerful method for providing information on exposure to ionising radiation many years after the event, since the 'signal' is 'stored' in the tooth or the bone. This technique is of particular relevance to relatively low dose exposures or when the results of conventional dosimetry are not available (e.g. in accidental circumstances). The use of EPR dosimetry, as an essential tool for retrospective assessment of radiation exposure is an important part of radioepidemiological studies and also provides data to select appropriate countermeasures based on retrospective evaluation of individual doses. Despite well established regulations and protocols for maintaining radiation protection dose limits, the assurance that these limits will not be exceeded cannot be guaranteed, thus providing new challenges for development of accurate methods of individual dose assessment. To meet some of these challenges, in 1998 the IAEA initiated a co-ordinated research project (CRP) with the objective to review the available methods, current research and development in EPR biodosimetry technology, which may be of practical use. The major goal of this CRP was to investigate the use of EPR biodosimetry for reconstruction of absorbed dose in tooth enamel with the aim of providing Member States with up-to-date, and generally agreed upon advice regarding the most suitable procedures and the best focus for their research. The co-ordinated research project was conducted over four years and this publication presents the results and findings by a group of investigators from different countries. The available cytogenetic methods for radiation dose assessment were

  15. Biomimetic air sampling for detection of low concentrations of molecules and bioagents : LDRD 52744 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Robert Clark

    2003-12-01

    Present methods of air sampling for low concentrations of chemicals like explosives and bioagents involve noisy and power hungry collectors with mechanical parts for moving large volumes of air. However there are biological systems that are capable of detecting very low concentrations of molecules with no mechanical moving parts. An example is the silkworm moth antenna which is a highly branched structure where each of 100 branches contains about 200 sensory 'hairs' which have dimensions of 2 microns wide by 100 microns long. The hairs contain about 3000 pores which is where the gas phase molecules enter the aqueous (lymph) phase for detection. Simulations of diffusion of molecules indicate that this 'forest' of hairs is 'designed' to maximize the extraction of the vapor phase molecules. Since typical molecules lose about 4 decades in diffusion constant upon entering the liquid phase, it is important to allow air diffusion to bring the molecule as close to the 'sensor' as possible. The moth acts on concentrations as low as 1000 molecules per cubic cm. (one part in 1e16). A 3-D collection system of these dimensions could be fabricated by micromachining techniques available at Sandia. This LDRD addresses the issues involved with extracting molecules from air onto micromachined structures and then delivering those molecules to microsensors for detection.

  16. EPR techniques for space biodosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Haskell, E.; Hayes, R.; Kenner, G.; Sholom, S.; Chumak, V.

    1996-12-31

    Retrospective dosimetry of tooth enamel has become an increasingly complex and difficult discipline to undertake while still attaining accuracy. The paper provides a review of the major obstacles, advances and pertinent phenomenon associated with low level retrospective dosimetry of human tooth enamel. Also covered is the many sources of error in EPR dosimetry, their potential solutions, as well as the different analysis and scanning techniques in use with their prospective pros and cons. Prospective directions for new approaches, methods, and instruments are also reviewed.

  17. Eyeglass Large Aperture, Lightweight Space Optics FY2000 - FY2002 LDRD Strategic Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Hyde, R

    2003-02-10

    differences in their requirements and implementations, the fundamental difficulty in utilizing large aperture optics is the same for all of these applications: It is extremely difficult to design large aperture space optics which are both optically precise and can meet the practical requirements for launch and deployment in space. At LLNL we have developed a new concept (Eyeglass) which uses large diffractive optics to solve both of these difficulties; greatly reducing both the mass and the tolerance requirements for large aperture optics. During previous LDRD-supported research, we developed this concept, built and tested broadband diffractive telescopes, and built 50 cm aperture diffraction-limited diffractive lenses (the largest in the world). This work is fully described in UCRL-ID-136262, Eyeglass: A Large Aperture Space Telescope. However, there is a large gap between optical proof-of-principle with sub-meter apertures, and actual 50 meter space telescopes. This gap is far too large (both in financial resources and in spacecraft expertise) to be filled internally at LLNL; implementation of large aperture diffractive space telescopes must be done externally using non-LLNL resources and expertise. While LLNL will never become the primary contractor and integrator for large space optical systems, our natural role is to enable these devices by developing the capability of producing very large diffractive optics. Accordingly, the purpose of the Large Aperture, Lightweight Space Optics Strategic Initiative was to develop the technology to fabricate large, lightweight diffractive lenses. The additional purpose of this Strategic Initiative was, of course, to demonstrate this lens-fabrication capability in a fashion compellingly enough to attract the external support necessary to continue along the path to full-scale space-based telescopes. During this 3 year effort (FY2000-FY2002) we have developed the capability of optically smoothing and diffractively-patterning thin meter

  18. A Complexity Science-Based Framework for Global Joint Operations Analysis to Support Force Projection: LDRD Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Lawton, Craig R.

    2015-01-01

    The military is undergoing a significant transformation as it modernizes for the information age and adapts to address an emerging asymmetric threat beyond traditional cold war era adversaries. Techniques such as traditional large-scale, joint services war gaming analysis are no longer adequate to support program evaluation activities and mission planning analysis at the enterprise level because the operating environment is evolving too quickly. New analytical capabilities are necessary to address modernization of the Department of Defense (DoD) enterprise. This presents significant opportunity to Sandia in supporting the nation at this transformational enterprise scale. Although Sandia has significant experience with engineering system of systems (SoS) and Complex Adaptive System of Systems (CASoS), significant fundamental research is required to develop modeling, simulation and analysis capabilities at the enterprise scale. This report documents an enterprise modeling framework which will enable senior level decision makers to better understand their enterprise and required future investments.

  19. Metastability and Delta-Phase Retention in Plutonium Alloys Final Report of LDRD Project 01-ERD-029

    Energy Technology Data Exchange (ETDEWEB)

    Wong, J; Schwartz, A J; Blobaum, K M; Krenn, C R; Wall, M A; Wolfer, W G; Haslam, J J; Moore, K T

    2004-02-11

    The {delta} to {alpha}' phase transformation in Pu-Ga alloys is intriguing for both scientific and technological reasons. On cooling, the ductile fcc {delta}-phase transforms martensitically to the brittle monoclinic {alpha}'-phase at approximately -120 C (depending on composition). This exothermic transformation involves a 20% volume contraction and a significant increase in resistivity. The reversion of {alpha}' to {delta} involves a large temperature hysteresis beginning just above room temperature. In an attempt to better understand the underlying thermodynamics and kinetics responsible for these unusual features, we have investigated the {delta} {leftrightarrow} {alpha}' phase transformations in a Pu-0.6 wt% Ga alloy using a combination of experimental and modeling techniques.

  20. Optics Performance at 1(omega), 2 (omega), and 3 (omega): Final Report on LDRD Project 03-ERD-071

    Energy Technology Data Exchange (ETDEWEB)

    Honig, J; Adams, J; Carr, C; Demos, S; Feit, M; Mehta, N; Norton, M; Nostrand, M; Rubenchik, A; Spaeth, M

    2006-02-08

    The interaction of intense laser light with dielectric materials is a fundamental applied science problem that is becoming increasingly important with the rapid development of ever more powerful lasers. To better understand the behavior of optical components in large fusion-class laser systems, we are systematically studying the interaction of high-fluence, high-power laser light with high-quality optical components, with particular interest on polishing/finishing and stress-induced defects and surface contamination. We focus on obtaining comparable measurements at three different wavelengths, 1{omega} (1053 nm), 2{omega} (527 nm), and 3{omega} (351 nm).

  1. Adaptive Optics Views of the Hubble Deep Fields Final report on LLNL LDRD Project 03-ERD-002

    Energy Technology Data Exchange (ETDEWEB)

    Max, C E; Gavel, D; Pennington, D; Gibbard, S; van Dam, M; Larkin, J; Koo, D; Raschke, L; Melbourne, J

    2007-02-17

    We used laser guide star adaptive optics at the Lick and Keck Observatories to study active galactic nuclei and galaxies, with emphasis on those in the early Universe. The goals were to observe large galaxies like our own Milky Way in the process of their initial assembly from sub-components, to identify central active galactic nuclei due to accreting black holes in galaxy cores, and to measure rates of star formation and evolution in galaxies. In the distant universe our focus was on the GOODS and GEMS fields (regions in the Northern and Southern sky that include the Hubble Deep Fields) as well as the Extended Groth Strip and COSMOS fields. Each of these parts of the sky has been intensively studied at multiple wavelengths by the Hubble Space Telescope, the Chandra X-Ray Observatory, the XMM Space Telescope, the Spitzer Space Telescope, and several ground-based telescopes including the Very Large Array radio interferometer, in order to gain an unbiased view of a significant statistical sample of galaxies in the early universe.

  2. A complexity science-based framework for global joint operations analysis to support force projection: LDRD Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawton, Craig R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). System Sustainment & Readiness Technologies Dept.

    2015-01-01

    The military is undergoing a significant transformation as it modernizes for the information age and adapts to address an emerging asymmetric threat beyond traditional cold war era adversaries. Techniques such as traditional large-scale, joint services war gaming analysis are no longer adequate to support program evaluation activities and mission planning analysis at the enterprise level because the operating environment is evolving too quickly. New analytical capabilities are necessary to address modernization of the Department of Defense (DoD) enterprise. This presents significant opportunity to Sandia in supporting the nation at this transformational enterprise scale. Although Sandia has significant experience with engineering system of systems (SoS) and Complex Adaptive System of Systems (CASoS), significant fundamental research is required to develop modeling, simulation and analysis capabilities at the enterprise scale. This report documents an enterprise modeling framework which will enable senior level decision makers to better understand their enterprise and required future investments.

  3. Final report on LDRD project: Semiconductor surface-emitting microcavity laser spectroscopy for analysis of biological cells and microstructures

    Energy Technology Data Exchange (ETDEWEB)

    Gourley, P.L.; McDonald, A.E. [Sandia National Labs., Albuquerque, NM (United States). Nanostructure and Semiconductor Physics Dept.; Gourley, M.F. [Washington Hospital Center, DC (United States); Bellum, J. [Coherent Technologies, Boulder, CO (United States)

    1997-08-01

    This article discusses a new intracavity laser technique that uses living or fixed cells as an integral part of the laser. The cells are placed on a GaAs based semiconductor wafer comprising one half of a vertical cavity surface-emitting laser. After placement, the cells are covered with a dielectric mirror to close the laser cavity. When photo-pumped with an external laser, this hybrid laser emits coherent light images and spectra that depend sensitively on the cell size, shape, and dielectric properties. The light spectra can be used to identify different cell types and distinguish normal and abnormal cells. The laser can be used to study single cells in real time as a cell-biology lab-on-a-chip, or to study large populations of cells by scanning the pump laser at high speed. The laser is well-suited to be integrated with other micro-optical or micro-fluidic components to lead to micro-optical-mechanical systems for analysis of fluids, particulates, and biological cells.

  4. Final LDRD report : enhanced spontaneous emission rate in visible III-nitride LEDs using 3D photonic crystal cavities.

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Arthur Joseph; Subramania, Ganapathi S.; Coley, Anthony J.; Lee, Yun-Ju; Li, Qiming; Wang, George T.; Luk, Ting Shan; Koleske, Daniel David; Fullmer, Kristine Wanta

    2009-09-01

    The fundamental spontaneous emission rate for a photon source can be modified by placing the emitter inside a periodic dielectric structure allowing the emission to be dramatically enhanced or suppressed depending on the intended application. We have investigated the relatively unexplored realm of interaction between semiconductor emitters and three dimensional photonic crystals in the visible spectrum. Although this interaction has been investigated at longer wavelengths, very little work has been done in the visible spectrum. During the course of this LDRD, we have fabricated TiO{sub 2} logpile photonic crystal structures with the shortest wavelength band gap ever demonstrated. A variety of different emitters with emission between 365 nm and 700 nm were incorporated into photonic crystal structures. Time-integrated and time-resolved photoluminescence measurements were performed to measure changes to the spontaneous emission rate. Both enhanced and suppressed emission were demonstrated and attributed to changes to the photonic density of states.

  5. Remark on the Regularities of Kato's Solutions to Navier-Stokes Equations with Initial Data in Ld(Rd)

    Institute of Scientific and Technical Information of China (English)

    Ping ZHANG

    2008-01-01

    Motivated by the results of J.Y.Chemin in "J.Anal.Math.,77,1999,27-50" and G.Furioli et al in "Revista Mat.Iberoamer.,16,2002,605-667",the author considers further regularities of the mild solutions to Navier-Stokes equation with initial data u0∈Ld(Rd).In particular,it is proved that if u∈C([0,T*); Ld(Rd)) is a mild solution of (NSv),then u(t,x) -evt△u0∈(L)∞ ((0,T); (B)1/d/2,∞)∩(L)1((0,T);(B)3/d/2,∞) for any T<T*.

  6. Eyeglass Large Aperture, Lightweight Space Optics FY2000 - FY2002 LDRD Strategic Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Hyde, R

    2003-02-10

    differences in their requirements and implementations, the fundamental difficulty in utilizing large aperture optics is the same for all of these applications: It is extremely difficult to design large aperture space optics which are both optically precise and can meet the practical requirements for launch and deployment in space. At LLNL we have developed a new concept (Eyeglass) which uses large diffractive optics to solve both of these difficulties; greatly reducing both the mass and the tolerance requirements for large aperture optics. During previous LDRD-supported research, we developed this concept, built and tested broadband diffractive telescopes, and built 50 cm aperture diffraction-limited diffractive lenses (the largest in the world). This work is fully described in UCRL-ID-136262, Eyeglass: A Large Aperture Space Telescope. However, there is a large gap between optical proof-of-principle with sub-meter apertures, and actual 50 meter space telescopes. This gap is far too large (both in financial resources and in spacecraft expertise) to be filled internally at LLNL; implementation of large aperture diffractive space telescopes must be done externally using non-LLNL resources and expertise. While LLNL will never become the primary contractor and integrator for large space optical systems, our natural role is to enable these devices by developing the capability of producing very large diffractive optics. Accordingly, the purpose of the Large Aperture, Lightweight Space Optics Strategic Initiative was to develop the technology to fabricate large, lightweight diffractive lenses. The additional purpose of this Strategic Initiative was, of course, to demonstrate this lens-fabrication capability in a fashion compellingly enough to attract the external support necessary to continue along the path to full-scale space-based telescopes. During this 3 year effort (FY2000-FY2002) we have developed the capability of optically smoothing and diffractively-patterning thin meter

  7. 4-wave mixing for phase-matching free nonlinear optics in quantum cascade structures : LDRD 08-0346 final report.

    Energy Technology Data Exchange (ETDEWEB)

    Chow, Weng Wah; Wanke, Michael Clement; Allen, Dan G.; Yang, Zhenshan; Waldmueller, Ines

    2010-10-01

    Optical nonlinearities and quantum coherences have the potential to enable efficient, high-temperature generation of coherent THz radiation. This LDRD proposal involves the exploration of the underlying physics using intersubband transitions in a quantum cascade structure. Success in the device physics aspect will give Sandia the state-of-the-art technology for high-temperature THz quantum cascade lasers. These lasers are useful for imaging and spectroscopy in medicine and national defense. Success may have other far-reaching consequences. Results from the in-depth study of coherences, dephasing and dynamics will eventually impact the fields of quantum computing, optical communication and cryptology, especially if we are successful in demonstrating entangled photons or slow light. An even farther reaching development is if we can show that the QC nanostructure, with its discrete atom-like intersubband resonances, can replace the atom in quantum optics experiments. Having such an 'artificial atom' will greatly improve flexibility and preciseness in experiments, thereby enhancing the discovery of new physics. This is because we will no longer be constrained by what natural can provide. Rather, one will be able to tailor transition energies and optical matrix elements to enhance the physics of interest. This report summarizes a 3-year LDRD program at Sandia National Laboratories exploring optical nonlinearities in intersubband devices. Experimental and theoretical investigations were made to develop a fundamental understanding of light-matter interaction in a semiconductor system and to explore how this understanding can be used to develop mid-IR to THz emitters and nonclassical light sources.

  8. Final LDRD report : design and fabrication of advanced device structures for ultra high efficiency solid state lighting.

    Energy Technology Data Exchange (ETDEWEB)

    Koleske, Daniel David; Bogart, Katherine Huderle Andersen; Shul, Randy John; Wendt, Joel Robert; Crawford, Mary Hagerott; Allerman, Andrew Alan; Fischer, Arthur Joseph

    2005-04-01

    The goal of this one year LDRD was to improve the overall efficiency of InGaN LEDs by improving the extraction of light from the semiconductor chip. InGaN LEDs are currently the most promising technology for producing high efficiency blue and green semiconductor light emitters. Improving the efficiency of InGaN LEDs will enable a more rapid adoption of semiconductor based lighting. In this LDRD, we proposed to develop photonic structures to improve light extraction from nitride-based light emitting diodes (LEDs). While many advanced device geometries were considered for this work, we focused on the use of a photonic crystal for improved light extraction. Although resonant cavity LEDs and other advanced structures certainly have the potential to improve light extraction, the photonic crystal approach showed the most promise in the early stages of this short program. The photonic crystal (PX)-LED developed here incorporates a two dimensional photonic crystal, or photonic lattice, into a nitride-based LED. The dimensions of the photonic crystal are selected such that there are very few or no optical modes in the plane of the LED ('lateral' modes). This will reduce or eliminate any radiation in the lateral direction so that the majority of the LED radiation will be in vertical modes that escape the semiconductor, which will improve the light-extraction efficiency. PX-LEDs were fabricated using a range of hole diameters and lattice constants and compared to control LEDs without a photonic crystal. The far field patterns from the PX-LEDs were dramatically modified by the presence of the photonic crystal. An increase in LED brightness of 1.75X was observed for light measured into a 40 degree emission cone with a total increase in power of 1.5X for an unencapsulated LED.

  9. Modular Pebble-Bed Reactor Project: Laboratory-Directed Research and Development Program FY 2002 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Petti, David Andrew; Dolan, Thomas James; Miller, Gregory Kent; Moore, Richard Leroy; Terry, William Knox; Ougouag, Abderrafi Mohammed-El-Ami; Oh, Chang H; Gougar, Hans D

    2002-11-01

    This report documents the results of our research in FY-02 on pebble-bed reactor technology under our Laboratory Directed Research and Development (LDRD) project entitled the Modular Pebble-Bed Reactor. The MPBR is an advanced reactor concept that can meet the energy and environmental needs of future generations under DOE’s Generation IV initiative. Our work is focused in three areas: neutronics, core design and fuel cycle; reactor safety and thermal hydraulics; and fuel performance.

  10. Ldrd-2015-00076 -- Validation Study Of The SRNL Vacuum Aerosol Contaminant Extractor

    Energy Technology Data Exchange (ETDEWEB)

    Siegfried, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-10-14

    SRNL recently developed a prototype device for the IAEA to prepare particulate samples collected on swipes for laboratory analysis. The Vacuum Aerosol Contaminant Extractor (VacACE) utilizes electrostatic precipitation in lieu of the impaction or ultrasonic solvent extraction methods presently employed by the IAEA to place particles of interest on carbon planchets for investigation. The project was funded by the Intentional Safeguards Projects Office (ISPO) with scope for device design and fabrication, but no scope for validation or testing. Without documented validation of the tool, sample processing and subsequent analysis fidelity cannot be assured. The goal of this project was to determine collection efficacy in a rigorous fashion, demonstrate proof of concept with standardized particulates, and produce a validated VacACE sampling protocol.

  11. Confined cooperative self-assembly and synthesis of optically and electrically active nanostructures : final LDRD report

    Energy Technology Data Exchange (ETDEWEB)

    Coker, Eric Nicholas; Haddad, Raid Edward (University of New Mexico, Albuquerque, NM); Fan, Hongyou; Ta, Anh (University of New Mexico, Albuquerque, NM); Bai, Feng (University of New Mexico, Albuquerque, NM); Rodriguez, Mark Andrew; Huang, Jian Yu

    2011-10-01

    In this project, we developed a confined cooperative self-assembly process to synthesize one-dimensional (1D) j-aggregates including nanowires and nanorods with controlled diameters and aspect ratios. The facile and versatile aqueous solution process assimilates photo-active macrocyclic building blocks inside surfactant micelles, forming stable single-crystalline high surface area nanoporous frameworks with well-defined external morphology defined by the building block packing. Characterizations using TEM, SEM, XRD, N{sub 2} and NO sorption isotherms, TGA, UV-vis spectroscopy, and fluorescence imaging and spectroscopy indicate that the j-aggregate nanostructures are monodisperse and may further assemble into hierarchical arrays with multi-modal functional pores. The nanostructures exhibit enhanced and collective optical properties over the individual chromophores. This project was a small footprint research effort which, nonetheless, produced significant progress towards both the stated goal as well as unanticipated research directions.

  12. Strategic partnerships final LDRD report : nanocomposite materials for efficient solar hydrogen production.

    Energy Technology Data Exchange (ETDEWEB)

    Corral, Erica L. (University of Arizona, Tucson, AZ); Miller, James Edward; Walker, Luke S. (University of Arizona, Tucson, AZ); Evans, Lindsey R.

    2012-05-01

    This 'campus executive' project sought to advance solar thermochemical technology for producing the chemical fuels. The project advanced the common interest of Sandia National Laboratories and the University of Arizona in creating a sustainable and viable alternative to fossil fuels. The focus of this effort was in developing new methods for creating unique monolithic composite structures and characterizing their performance in thermochemical production of hydrogen from water. The development and processing of the materials was undertaken in the Materials Science and Engineering Department at the University of Arizona; Sandia National Laboratories performed the thermochemical characterization. Ferrite/yttria-stabilized zirconia composite monoliths were fabricated and shown to have exceptionally high utilization of the ferrite for splitting CO{sub 2} to obtain CO (a process analogous to splitting H{sub 2}O to obtain H{sub 2}).

  13. LDRD final report : leveraging multi-way linkages on heterogeneous data.

    Energy Technology Data Exchange (ETDEWEB)

    Dunlavy, Daniel M.; Kolda, Tamara Gibson (Sandia National Laboratories, Livermore, CA)

    2010-09-01

    This report is a summary of the accomplishments of the 'Leveraging Multi-way Linkages on Heterogeneous Data' which ran from FY08 through FY10. The goal was to investigate scalable and robust methods for multi-way data analysis. We developed a new optimization-based method called CPOPT for fitting a particular type of tensor factorization to data; CPOPT was compared against existing methods and found to be more accurate than any faster method and faster than any equally accurate method. We extended this method to computing tensor factorizations for problems with incomplete data; our results show that you can recover scientifically meaningfully factorizations with large amounts of missing data (50% or more). The project has involved 5 members of the technical staff, 2 postdocs, and 1 summer intern. It has resulted in a total of 13 publications, 2 software releases, and over 30 presentations. Several follow-on projects have already begun, with more potential projects in development.

  14. Evaluation of applying γ-H2AX as a radiation biodosimetry with an animal model%γ-H2AX用于辐射生物剂量计研究的动物模型评价

    Institute of Scientific and Technical Information of China (English)

    王晶; 张亚平; 丁德芳; 高赟; 张旭霞; 张俊香; 陈红红

    2015-01-01

    Objective To evaluate the potential feasibility of γ-H2AX foci as a biodosimetry after exposure to ionizing radiation by comparing DNA double-strand break repair kinetics in rat blood lymphocytes with that in human lymphocytes.Methods Peripheral blood lymphocytes separated from Sprague-Dawley(SD) male rats and healthy adults were exposed to γ-rays,and some rats were also subjected to total body irradiation.The inductions of DNA repair-related foci of γ-H2AX,pATM (S1981) and pDNA-PKcs (T2609) were detected with immunofluorescence staining technique at different time points post-irradiation,and the status of their co-localization was analyzed.Results The induction kinetics of γ-H2AX foci in rat lymphocytes was similar to that observed in human lymphocytes.The frequencies of γ-H2AX foci peaked at 30 min after γ-ray irradiation (trst =62.64,th =28.52,P < 0.05),then decreased rapidly after 6 h post-irradiation (trat =45.96,th =14.80,P <0.05),and the residual foci number remained only about 3%-8% of its maximal value at 24 h post-irradiation.At 30 min after γ-ray irradiation,the frequencies of pATM (S1981) and pDNA-PKcs (T2609) foci in rat and human lymphocytes significantly higher than those of nonirradiated control (trat =21.05,25.80,th =11.07,29.52,P < 0.05),and the frequencies of co-localization of pATM (S1981) or pDNA-PKcs (T2609) foci with γ-H2AX foci also markedly increased by 26%-32% in irradiated lymphocytes of rat and human (trat =5.34,9.14,thuman =18.32,51.28,P <0.05).Moreover,γ-H2AX foci incidence in rat lymphocytes in vitro was consistent with that induced by total body irradiation of rat.The number of γ-H2AX foci in irradiated rat lymphocytes increased with irradiation dose in a linear dose-dependent manner,its slope was similar to that of irradiated human lymphocytes reported by other laboratory.Conclusions Rat is a useful animal model to evaluate radiation biodosimetry with γ-H2AX foci in lymphocytes.The co-activation of ATM and

  15. LDRD final report on Bloch Oscillations in two-dimensional nanostructure arrays for high frequency applications.

    Energy Technology Data Exchange (ETDEWEB)

    Lyo, Sungkwun Kenneth; Pan, Wei; Reno, John Louis; Wendt, Joel Robert; Barton, Daniel Lee

    2008-09-01

    We have investigated the physics of Bloch oscillations (BO) of electrons, engineered in high mobility quantum wells patterned into lateral periodic arrays of nanostructures, i.e. two-dimensional (2D) quantum dot superlattices (QDSLs). A BO occurs when an electron moves out of the Brillouin zone (BZ) in response to a DC electric field, passing back into the BZ on the opposite side. This results in quantum oscillations of the electron--i.e., a high frequency AC current in response to a DC voltage. Thus, engineering a BO will yield continuously electrically tunable high-frequency sources (and detectors) for sensor applications, and be a physics tour-de-force. More than a decade ago, Bloch oscillation (BO) was observed in a quantum well superlattice (QWSL) in short-pulse optical experiments. However, its potential as electrically biased high frequency source and detector so far has not been realized. This is partially due to fast damping of BO in QWSLs. In this project, we have investigated the possibility of improving the stability of BO by fabricating lateral superlattices of periodic coupled nanostructures, such as metal grid, quantum (anti)dots arrays, in high quality GaAs/Al{sub x}Ga{sub 1-x}As heterostructures. In these nanostructures, the lateral quantum confinement has been shown theoretically to suppress the optical-phonon scattering, believed to be the main mechanism for fast damping of BO in QWSLs. Over the last three years, we have made great progress toward demonstrating Bloch oscillations in QDSLs. In the first two years of this project, we studied the negative differential conductance and the Bloch radiation induced edge-magnetoplasmon resonance. Recently, in collaboration with Prof. Kono's group at Rice University, we investigated the time-domain THz magneto-spectroscopy measurements in QDSLs and two-dimensional electron systems. A surprising DC electrical field induced THz phase flip was observed. More measurements are planned to investigate this

  16. Final report for the endowment of simulator agents with human-like episodic memory LDRD.

    Energy Technology Data Exchange (ETDEWEB)

    Speed, Ann Elizabeth; Lippitt, Carl Edward; Thomas, Edward Victor; Xavier, Patrick Gordon; Forsythe, Christi A.; Schaller, Mark J.; Schoenwald, David Alan

    2003-12-01

    This report documents work undertaken to endow the cognitive framework currently under development at Sandia National Laboratories with a human-like memory for specific life episodes. Capabilities have been demonstrated within the context of three separate problem areas. The first year of the project developed a capability whereby simulated robots were able to utilize a record of shared experience to perform surveillance of a building to detect a source of smoke. The second year focused on simulations of social interactions providing a queriable record of interactions such that a time series of events could be constructed and reconstructed. The third year addressed tools to promote desktop productivity, creating a capability to query episodic logs in real time allowing the model of a user to build on itself based on observations of the user's behavior.

  17. Scalable Entity-Based Modeling of Population-Based Systems, Final LDRD Report

    Energy Technology Data Exchange (ETDEWEB)

    Cleary, A J; Smith, S G; Vassilevska, T K; Jefferson, D R

    2005-01-27

    The goal of this project has been to develop tools, capabilities and expertise in the modeling of complex population-based systems via scalable entity-based modeling (EBM). Our initial focal application domain has been the dynamics of large populations exposed to disease-causing agents, a topic of interest to the Department of Homeland Security in the context of bioterrorism. In the academic community, discrete simulation technology based on individual entities has shown initial success, but the technology has not been scaled to the problem sizes or computational resources of LLNL. Our developmental emphasis has been on the extension of this technology to parallel computers and maturation of the technology from an academic to a lab setting.

  18. Final LDRD report : advanced materials for next generation high-efficiency thermochemistry.

    Energy Technology Data Exchange (ETDEWEB)

    Ambrosini, Andrea; Miller, James Edward; Allendorf, Mark D. [Sandia National Laboratories, Livermore, CA; Coker, Eric Nicholas; Ermanoski, Ivan; Hogan, Roy E.,; McDaniel, Anthony H. [Sandia National Laboratories, Livermore, CA

    2014-01-01

    Despite rapid progress, solar thermochemistry remains high risk; improvements in both active materials and reactor systems are needed. This claim is supported by studies conducted both prior to and as part of this project. Materials offer a particular large opportunity space as, until recently, very little effort apart from basic thermodynamic analysis was extended towards understanding this most fundamental component of a metal oxide thermochemical cycle. Without this knowledge, system design was hampered, but more importantly, advances in these crucial materials were rare and resulted more from intuition rather than detailed insight. As a result, only two basic families of potentially viable solid materials have been widely considered, each of which has significant challenges. Recent efforts towards applying an increased level of scientific rigor to the study of thermochemical materials have provided a much needed framework and insights toward developing the next generation of highly improved thermochemically active materials. The primary goal of this project was to apply this hard-won knowledge to rapidly advance the field of thermochemistry to produce a material within 2 years that is capable of yielding CO from CO2 at a 12.5 % reactor efficiency. Three principal approaches spanning a range of risk and potential rewards were pursued: modification of known materials, structuring known materials, and identifying/developing new materials for the application. A newly developed best-of-class material produces more fuel (9x more H2, 6x more CO) under milder conditions than the previous state of the art. Analyses of thermochemical reactor and system efficiencies and economics were performed and a new hybrid concept was reported. The larger case for solar fuels was also further refined and documented.

  19. Mesoscale wide-bandwidth linear magnetic actuators : an LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Lawrence Anthony

    2004-02-01

    As MEMS transducers are scaled up in size, the threshold is quickly crossed to where magnetoquasistatic (MQS) transducers are superior for force production compared to electroquasistatic (EQS) transducers. Considerable progress has been made increasing the force output of MEMS EQS transducers, but progress with MEMS MQS transducers has been more modest. A key reason for this has been the difficulty implementing efficient lithographically-fabricated magnetic coil structures. The contribution of this study is a planar multilayer polyphase coil architecture which provides for the lithographic implementation of efficient stator windings suitable for linear magnetic machines. A millimeter-scale linear actuator with complex stator windings was fabricated using this architecture. The stators of the actuator were fabricated using a BCB/Cu process, which does not require replanarization of the wafer between layers. The prototype stator was limited to thin copper layers (3 {micro}m) due to the use of evaporated metal at the time of fabrication. Two layers of metal were implemented in the prototype, but the winding architecture naturally supports additional metal layer pairs. It was found in laboratory tests that the windings can support very high current densities of 4 x 10{sup 9}A/m{sup 2} without damage. Force production normal to the stator was calculated to be 0.54 N/A. For thin stators such as this one, force production increases approximately linearly with the thickness of the windings and a six-layer stator fabricated using a newly implemented electroplated BCB/Cu process (six layers of 15 {micro}m thick metal) is projected to produce approximately 8.8 N/A.

  20. CORSICA: A comprehensive simulation of toroidal magnetic-fusion devices. Final report to the LDRD Program

    Energy Technology Data Exchange (ETDEWEB)

    Crotinger, J.A.; LoDestro, L.; Pearlstein, L.D.; Tarditi, A.; Casper, T.A.; Hooper, E.B.

    1997-03-21

    In 1992, our group began exploring the requirements for a comprehensive simulation code for toroidal magnetic fusion experiments. There were several motivations for taking this step. First, the new machines being designed were much larger and more expensive than current experiments. Second, these new designs called for much more sophisticated control of the plasma shape and position, as well as the distributions of energy, mass, and current within the plasma. These factors alone made it clear that a comprehensive simulation capability would be an extremely valuable tool for machine design. The final motivating factor was that the national Numerical Tokamak Project (NTP) had recently received High Performance Computing and Communications (HPCC) Grand Challenge funding to model turbulent transport in tokamaks, raising the possibility that first-principles simulations of this process might be practical in the near future. We felt that the best way to capitalize on this development was to integrate the resulting turbulence simulation codes into a comprehensive simulation. Such simulations must include the effects of many microscopic length- and time-scales. In order to do a comprehensive simulation efficiently, the length- and time- scale disparities must be exploited. We proposed to do this by coupling the average or quasistatic effects from the fast time-scales to a slow-time-scale transport code for the macroscopic plasma evolution. In FY93-FY96 we received funding to investigate algorithms for computationally coupling such disparate-scale simulations and to implement these algorithms in a prototype simulation code, dubbed CORSICA. Work on algorithms and test cases proceeded in parallel, with the algorithms being incorporated into CORSICA as they became mature. In this report we discuss the methods and algorithms, the CORSICA code, its applications, and our plans for the future.

  1. Peer-to-peer architectures for exascale computing : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Vorobeychik, Yevgeniy; Mayo, Jackson R.; Minnich, Ronald G.; Armstrong, Robert C.; Rudish, Donald W.

    2010-09-01

    platforms. P2P architectures give us a starting point for crafting applications and system software for exascale. In the context of the Internet, P2P applications (e.g., file sharing, botnets) have already solved this problem for 10{sup 6}-10{sup 7} nodes. Usually based on a fractal distributed hash table structure, these systems have proven robust in practice to constant and unpredictable outages, failures, and even subversion. For example, a recent estimate of botnet turnover (i.e., the number of machines leaving and joining) is about 11% per week. Nonetheless, P2P networks remain effective despite these failures: The Conficker botnet has grown to {approx} 5 x 10{sup 6} peers. Unlike today's system software and applications, those for next-generation exascale machines cannot assume a static structure and, to be scalable over millions of nodes, must be decentralized. P2P architectures achieve both, and provide a promising model for 'fault-oblivious computing'. This project aimed to study the dynamics of P2P networks in the context of a design for exascale systems and applications. Having no single point of failure, the most successful P2P architectures are adaptive and self-organizing. While there has been some previous work applying P2P to message passing, little attention has been previously paid to the tightly coupled exascale domain. Typically, the per-node footprint of P2P systems is small, making them ideal for HPC use. The implementation on each peer node cooperates en masse to 'heal' disruptions rather than relying on a controlling 'master' node. Understanding this cooperative behavior from a complex systems viewpoint is essential to predicting useful environments for the inextricably unreliable exascale platforms of the future. We sought to obtain theoretical insight into the stability and large-scale behavior of candidate architectures, and to work toward leveraging Sandia's Emulytics platform to test promising candidates

  2. Final LDRD report :

    Energy Technology Data Exchange (ETDEWEB)

    Kronawitter, Coleman X.; Antoun, Bonnie R.; Mao, Samuel S.

    2012-01-01

    The distinction between electricity and fuel use in analyses of global power consumption statistics highlights the critical importance of establishing efficient synthesis techniques for solar fuelsthose chemicals whose bond energies are obtained through conversion processes driven by solar energy. Photoelectrochemical (PEC) processes show potential for the production of solar fuels because of their demonstrated versatility in facilitating optoelectronic and chemical conversion processes. Tandem PEC-photovoltaic modular configurations for the generation of hydrogen from water and sunlight (solar water splitting) provide an opportunity to develop a low-cost and efficient energy conversion scheme. The critical component in devices of this type is the PEC photoelectrode, which must be optically absorptive, chemically stable, and possess the required electronic band alignment with the electrochemical scale for its charge carriers to have sufficient potential to drive the hydrogen and oxygen evolution reactions. After many decades of investigation, the primary technological obstacle remains the development of photoelectrode structures capable of efficient conversion of light with visible frequencies, which is abundant in the solar spectrum. Metal oxides represent one of the few material classes that can be made photoactive and remain stable to perform the required functions.

  3. LDRD final report :

    Energy Technology Data Exchange (ETDEWEB)

    Brost, Randolph C.; McLendon, William Clarence,

    2013-01-01

    Modeling geospatial information with semantic graphs enables search for sites of interest based on relationships between features, without requiring strong a priori models of feature shape or other intrinsic properties. Geospatial semantic graphs can be constructed from raw sensor data with suitable preprocessing to obtain a discretized representation. This report describes initial work toward extending geospatial semantic graphs to include temporal information, and initial results applying semantic graph techniques to SAR image data. We describe an efficient graph structure that includes geospatial and temporal information, which is designed to support simultaneous spatial and temporal search queries. We also report a preliminary implementation of feature recognition, semantic graph modeling, and graph search based on input SAR data. The report concludes with lessons learned and suggestions for future improvements.

  4. Project 2010 Project Management

    CERN Document Server

    Happy, Robert

    2010-01-01

    The ideal on-the-job reference guide for project managers who use Microsoft Project 2010. This must-have guide to using Microsoft Project 2010 is written from a real project manager's perspective and is packed with information you can use on the job. The book explores using Project 2010 during phases of project management, reveals best practices, and walks you through project flow from planning through tracking to closure. This valuable book follows the processes defined in the PMBOK Guide, Fourth Edition , and also provides exam prep for Microsoft's MCTS: Project 2010 certification.: Explains

  5. A progress report on the LDRD project entitled {open_quotes}Microelectronic silicon-based chemical sensors: Ultradetection of high value molecules{close_quotes}

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, R.C.

    1996-09-01

    This work addresses a new kind of silicon based chemical sensor that combines the reliability and stability of silicon microelectronic field effect devices with the highly selective and sensitive immunoassay. The sensor works on the principle that thin SiN layers on lightly doped Si can detect pH changes rapidly and reversibly. The pH changes affect the surface potential, and that can be quickly determined by pulsed photovoltage measurements. To detect other species, chemically sensitive films were deposited on the SiN where the presence of the chosen analyte results in pH changes through chemical reactions. A invention of a cell sorting device based on these principles is also described. A new method of immobilizing enzymes using Sandia`s sol-gel glasses is documented and biosensors based on the silicon wafer and an amperometric technique are detailed.

  6. Magnetically applied pressure-shear : a new technique for direct strength measurement at high pressure (final report for LDRD project 117856).

    Energy Technology Data Exchange (ETDEWEB)

    Lamppa, Derek C.; Haill, Thomas A.; Alexander, C. Scott; Asay, James Russell

    2010-09-01

    A new experimental technique to measure material shear strength at high pressures has been developed for use on magneto-hydrodynamic (MHD) drive pulsed power platforms. By applying an external static magnetic field to the sample region, the MHD drive directly induces a shear stress wave in addition to the usual longitudinal stress wave. Strength is probed by passing this shear wave through a sample material where the transmissible shear stress is limited to the sample strength. The magnitude of the transmitted shear wave is measured via a transverse VISAR system from which the sample strength is determined.

  7. Final report on LDRD project: Low-cost Pd-catalyzed metallization technology for rapid prototyping of electronic substrates and devices

    Energy Technology Data Exchange (ETDEWEB)

    Chen, K.S.; Morgan, W.P.; Zich, J.L.

    1998-02-01

    A low-cost, thermally-activated, palladium-catalyzed metallization process was developed for rapid prototyping of polymeric electronic substrates and devices. The process was successfully applied in producing adhesiveless copper/polyimide laminates with high peel strengths and thick copper coating; copper/polyimide laminates are widely used in fabricating interconnects such as printed wiring boards (PWBs) and flexible circuits. Also successfully metallized using this low-cost metallization process were: (1) scaled-down models of radar-and-communication antenna and waveguide; (2) scaled-down model of pulsed-power-accelerator electrode; (3) three-dimensional micro-porous, open-cell vitreous carbon foams. Moreover, additive patterned metallization was successfully achieved by selectively printing or plotting the catalyst ink only on areas where metallization is desired, and by uniform thermal activation. Additive patterned metallization eliminates the time-consuming, costly and environmentally-unfriendly etching process that is routinely carried out in conventional subtractive patterned metallization. A metallization process via ultraviolet (UV) irradiation activation was also demonstrated. In this process palladium-catalyst solution is first uniformly coated onto the substrate. A masking pattern is used to cover the areas where metallization is not wanted. UV irradiation is applied uniformly to activate the palladium catalyst and to cure the polymer carrier in areas that are not covered by the mask. Metal is then deposited by electroless plating only or by a combination of electroless and electrolytic plating. This UV-activation technique is particularly useful in additive fine-line patterned metallization. Lastly, computer models for electrolytic and electroless plating processes were developed to provide guidance in plating-process design.

  8. Uncertainty quantification of US Southwest climate from IPCC projections.

    Energy Technology Data Exchange (ETDEWEB)

    Boslough, Mark Bruce Elrick

    2011-01-01

    The Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4) made extensive use of coordinated simulations by 18 international modeling groups using a variety of coupled general circulation models (GCMs) with different numerics, algorithms, resolutions, physics models, and parameterizations. These simulations span the 20th century and provide forecasts for various carbon emissions scenarios in the 21st century. All the output from this panoply of models is made available to researchers on an archive maintained by the Program for Climate Model Diagnosis and Intercomparison (PCMDI) at LLNL. I have downloaded this data and completed the first steps toward a statistical analysis of these ensembles for the US Southwest. This constitutes the final report for a late start LDRD project. Complete analysis will be the subject of a forthcoming report.

  9. R&D for computational cognitive and social models : foundations for model evaluation through verification and validation (final LDRD report).

    Energy Technology Data Exchange (ETDEWEB)

    Slepoy, Alexander; Mitchell, Scott A.; Backus, George A.; McNamara, Laura A.; Trucano, Timothy Guy

    2008-09-01

    Sandia National Laboratories is investing in projects that aim to develop computational modeling and simulation applications that explore human cognitive and social phenomena. While some of these modeling and simulation projects are explicitly research oriented, others are intended to support or provide insight for people involved in high consequence decision-making. This raises the issue of how to evaluate computational modeling and simulation applications in both research and applied settings where human behavior is the focus of the model: when is a simulation 'good enough' for the goals its designers want to achieve? In this report, we discuss two years' worth of review and assessment of the ASC program's approach to computational model verification and validation, uncertainty quantification, and decision making. We present a framework that extends the principles of the ASC approach into the area of computational social and cognitive modeling and simulation. In doing so, we argue that the potential for evaluation is a function of how the modeling and simulation software will be used in a particular setting. In making this argument, we move from strict, engineering and physics oriented approaches to V&V to a broader project of model evaluation, which asserts that the systematic, rigorous, and transparent accumulation of evidence about a model's performance under conditions of uncertainty is a reasonable and necessary goal for model evaluation, regardless of discipline. How to achieve the accumulation of evidence in areas outside physics and engineering is a significant research challenge, but one that requires addressing as modeling and simulation tools move out of research laboratories and into the hands of decision makers. This report provides an assessment of our thinking on ASC Verification and Validation, and argues for further extending V&V research in the physical and engineering sciences toward a broader program of model

  10. Status of LDRD-DR 20070518 development of a magnetically driven target for thermo-nuclear burn studies (u)

    Energy Technology Data Exchange (ETDEWEB)

    Watt, Robert G [Los Alamos National Laboratory; Atchison, W L [Los Alamos National Laboratory; Colgate, S A [Los Alamos National Laboratory; Goforth, J [Los Alamos National Laboratory; Griego, J [Los Alamos National Laboratory; Guzik, J [Los Alamos National Laboratory; Holtkamp, D [Los Alamos National Laboratory; Idzorek, G [Los Alamos National Laboratory; Kirkpatrick, R [Los Alamos National Laboratory; Menikoff, R [Los Alamos National Laboratory; Meyer, R [Los Alamos National Laboratory; Oona, H [Los Alamos National Laboratory; Reardon, P [Los Alamos National Laboratory; Rousculp, C L [Los Alamos National Laboratory; Sgro, A G [Los Alamos National Laboratory; Tabaka, L [Los Alamos National Laboratory

    2010-01-20

    This project is developing a magnetically driven cylindrical confinement system for the creation of a small region of material existing under extreme conditions. Using a Ranchero High Explosive Pulsed Power generator (HEPP) with maximum current ranging from 25- 50 MA depending on the load, a current driven Al cylinder will impact a series of nested, less massive Au shells. Each subsequent shell's inner surface velocity will increase due to it's smaller mass by the ratio 2.01( 1+ m{sub i+ 1}/m i), along with radial convergence. Attaining this ideal result requires highly efficient energy transfer which in turn requires plastic cushions. The final velocity of the last sequential shell will be used to drive a central experimental package in which extreme material conditions will be produced. The inexpensive nature of HEPP and the extreme conditions attainable allow many studies to be conducted in regimes not currently available in the laboratory. One potential central experimental package consists of a cylindrical Inertial Confinement Fusion (ICF) target; a cylindrical Au pusher surrounding frozen DT. This target is used as a design tool. The ICF conditions achieved with such a target would be similar to those created in a double shell ignition capsule at the National Ignition Facility. The system being developed has a range of potential applications.

  11. Projects Work!

    Science.gov (United States)

    Textor, Martin R.

    2005-01-01

    The great educational value of projects is emphasized by contrasting negative aspects of the life of today's children with the goals of project work. This is illustrated by a project "Shopping." It is shown what children are learning in such projects and what the advantages of project work are. Relevant topic areas, criteria for selecting a…

  12. Intending Projects

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Project name: 90,000t/a BR device and auxiliary projects Construction unit: Sinopec Beijing Yanshan Petrochemical Company Total investment: 2.257 billion yuan Project description: It will cover an area of 14. lha.

  13. Overview of the SHIELDS Project at LANL

    Science.gov (United States)

    Jordanova, V.; Delzanno, G. L.; Henderson, M. G.; Godinez, H. C.; Jeffery, C. A.; Lawrence, E. C.; Meierbachtol, C.; Moulton, D.; Vernon, L.; Woodroffe, J. R.; Toth, G.; Welling, D. T.; Yu, Y.; Birn, J.; Thomsen, M. F.; Borovsky, J.; Denton, M.; Albert, J.; Horne, R. B.; Lemon, C. L.; Markidis, S.; Young, S. L.

    2015-12-01

    The near-Earth space environment is a highly dynamic and coupled system through a complex set of physical processes over a large range of scales, which responds nonlinearly to driving by the time-varying solar wind. Predicting variations in this environment that can affect technologies in space and on Earth, i.e. "space weather", remains a big space physics challenge. We present a recently funded project through the Los Alamos National Laboratory (LANL) Directed Research and Development (LDRD) program that is developing a new capability to understand, model, and predict Space Hazards Induced near Earth by Large Dynamic Storms, the SHIELDS framework. The project goals are to specify the dynamics of the hot (keV) particles (the seed population for the radiation belts) on both macro- and micro-scale, including important physics of rapid particle injection and acceleration associated with magnetospheric storms/substorms and plasma waves. This challenging problem is addressed using a team of world-class experts in the fields of space science and computational plasma physics and state-of-the-art models and computational facilities. New data assimilation techniques employing data from LANL instruments on the Van Allen Probes and geosynchronous satellites are developed in addition to physics-based models. This research will provide a framework for understanding of key radiation belt drivers that may accelerate particles to relativistic energies and lead to spacecraft damage and failure. The ability to reliably distinguish between various modes of failure is critically important in anomaly resolution and forensics. SHIELDS will enhance our capability to accurately specify and predict the near-Earth space environment where operational satellites reside.

  14. Project Management

    DEFF Research Database (Denmark)

    Project Management Theory Meets Practice contains the proceedings from the 1st Danish Project Management Research Conference (DAPMARC 2015), held in Copenhagen, Denmark, on May 21st, 2015.......Project Management Theory Meets Practice contains the proceedings from the 1st Danish Project Management Research Conference (DAPMARC 2015), held in Copenhagen, Denmark, on May 21st, 2015....

  15. Project Management

    DEFF Research Database (Denmark)

    Pilkington, Alan; Chai, Kah-Hin; Le, Yang

    2015-01-01

    This paper identifies the true coverage of PM theory through a bibliometric analysis of the International Journal of Project Management from 1996-2012. We identify six persistent research themes: project time management, project risk management, programme management, large-scale project management......, project success/failure and practitioner development. These differ from those presented in review and editorial articles in the literature. In addition, topics missing from the PM BOK: knowledge management project-based organization and project portfolio management have become more popular topics...

  16. Project Temporalities

    DEFF Research Database (Denmark)

    Tryggestad, Kjell; Justesen, Lise; Mouritsen, Jan

    2013-01-01

    into account. This may require investments in new project management technologies. Originality/value – This paper adds to the literatures on project temporalities and stakeholder theory by connecting them to the question of non-human stakeholders and to project management technologies.......Purpose – The purpose of this paper is to explore how animals can become stakeholders in interaction with project management technologies and what happens with project temporalities when new and surprising stakeholders become part of a project and a recognized matter of concern to be taken...... into account. Design/methodology/approach – The paper is based on a qualitative case study of a project in the building industry. The authors use actor-network theory (ANT) to analyze the emergence of animal stakeholders, stakes and temporalities. Findings – The study shows how project temporalities can...

  17. Intending Projects

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Project name: New construction project of production,research & development base of hydraulic system Construction site: Qingpu Industrial Park Construction unit: Parker Hannifin Industrial Hydraulic Technology (Shanghai) Co., Ltd.

  18. Alzheimer's Project

    Medline Plus

    Full Text Available ... Momentum in Science, Part 2" (70 minutes) Be a part of something big. HBO's "THE ALZHEIMER'S PROJECT" ... vital research and services. "THE ALZHEIMER'S PROJECT" is a presentation of HBO Documentary Films and the National ...

  19. Alzheimer's Project

    Science.gov (United States)

    ... state Home > News & Events > Upcoming Events > HBO Alzheimer’s Project In the News Walk to End Alzheimer's Upcoming ... Disease Awareness Month World Alzheimer's Month HBO Alzheimer’s Project MAKE A DONATION Your gift will help us ...

  20. Virtual projects

    DEFF Research Database (Denmark)

    Svejvig, Per; Commisso, Trine Hald

    2012-01-01

    Virtual projects are common with global competition, market development, and not least the financial crisis forcing organizations to reduce their costs drastically. Organizations therefore have to place high importance on ways to carry out virtual projects and consider appropriate practices...... that the best practice knowledge has not permeated sufficiently to the practice. Furthermore, the appropriate application of information and communication technology (ICT) remains a big challenge, and finally project managers are not sufficiently trained in organizing and conducting virtual projects...

  1. Project Management

    OpenAIRE

    Lörinc, Jan

    2012-01-01

    This work deals with the problems in the process of project management in enterprises. It examines the precise approaches, the possibility of standardizingthe approach to project team management and motivation of its members and their role in the process of project management. He confronts the views and attitudes of selected authors. The theoretical conclusions of findings compares with knowledgeacquired from research carried out on project management in a selected company.Evaluates managemen...

  2. Project ethics

    CERN Document Server

    Jonasson, Haukur Ingi

    2013-01-01

    How relevant is ethics to project management? The book - which aims to demystify the field of ethics for project managers and managers in general - takes both a critical and a practical look at project management in terms of success criteria, and ethical opportunities and risks. The goal is to help the reader to use ethical theory to further identify opportunities and risks within their projects and thereby to advance more directly along the path of mature and sustainable managerial practice.

  3. Define Project

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas

    2005-01-01

    "Project" is a key concept in IS management. The word is frequently used in textbooks and standards. Yet we seldom find a precise definition of the concept. This paper discusses how to define the concept of a project. The proposed definition covers both heavily formalized projects and informally ...

  4. International Projects

    CERN Document Server

    2002-01-01

    Description of co-operation projects implemented with the help of Sweden is presented. Information on performance of Phare and IAEA Regional and National Technical Cooperation projects is provided. Phare project 'Creation of Radiation Protection Infrastructure and Development of Supporting Services' was started in 2002

  5. Map Projection

    CERN Document Server

    Ghaderpour, Ebrahim

    2014-01-01

    In this paper, we introduce some known map projections from a model of the Earth to a flat sheet of paper or map and derive the plotting equations for these projections. The first fundamental form and the Gaussian fundamental quantities are defined and applied to obtain the plotting equations and distortions in length, shape and size for some of these map projections.

  6. Alzheimer's Project

    Medline Plus

    Full Text Available ... voluntary health organization in Alzheimer's care, support and research, the Alzheimer's Association has been an active partner in "THE ALZHEIMER'S PROJECT," ... (48 minutes) "Momentum ...

  7. Automating dicentric chromosome detection from cytogenetic biodosimetry data.

    Science.gov (United States)

    Rogan, Peter K; Li, Yanxin; Wickramasinghe, Asanka; Subasinghe, Akila; Caminsky, Natasha; Khan, Wahab; Samarabandu, Jagath; Wilkins, Ruth; Flegal, Farrah; Knoll, Joan H

    2014-06-01

    We present a prototype software system with sufficient capacity and speed to estimate radiation exposures in a mass casualty event by counting dicentric chromosomes (DCs) in metaphase cells from many individuals. Top-ranked metaphase cell images are segmented by classifying and defining chromosomes with an active contour gradient vector field (GVF) and by determining centromere locations along the centreline. The centreline is extracted by discrete curve evolution (DCE) skeleton branch pruning and curve interpolation. Centromere detection minimises the global width and DAPI-staining intensity profiles along the centreline. A second centromere is identified by reapplying this procedure after masking the first. Dicentrics can be identified from features that capture width and intensity profile characteristics as well as local shape features of the object contour at candidate pixel locations. The correct location of the centromere is also refined in chromosomes with sister chromatid separation. The overall algorithm has both high sensitivity (85 %) and specificity (94 %). Results are independent of the shape and structure of chromosomes in different cells, or the laboratory preparation protocol followed. The prototype software was recoded in C++/OpenCV; image processing was accelerated by data and task parallelisation with Message Passaging Interface and Intel Threading Building Blocks and an asynchronous non-blocking I/O strategy. Relative to a serial process, metaphase ranking, GVF and DCE are, respectively, 100 and 300-fold faster on an 8-core desktop and 64-core cluster computers. The software was then ported to a 1024-core supercomputer, which processed 200 metaphase images each from 1025 specimens in 1.4 h.

  8. Automating dicentric chromosome detection from cytogenetic bio-dosimetry data

    International Nuclear Information System (INIS)

    We present a prototype software system with sufficient capacity and speed to estimate radiation exposures in a mass casualty event by counting dicentric chromosomes (DCs) in metaphase cells from many individuals. Top-ranked metaphase cell images are segmented by classifying and defining chromosomes with an active contour gradient vector field (GVF) and by determining centromere locations along the centreline. The centreline is extracted by discrete curve evolution (DCE) skeleton branch pruning and curve interpolation. Centromere detection minimises the global width and DAPI-staining intensity profiles along the centreline. A second centromere is identified by reapplying this procedure after masking the first. Dicentrics can be identified from features that capture width and intensity profile characteristics as well as local shape features of the object contour at candidate pixel locations. The correct location of the centromere is also refined in chromosomes with sister chromatid separation. The overall algorithm has both high sensitivity (85 %) and specificity (94 %). Results are independent of the shape and structure of chromosomes in different cells, or the laboratory preparation protocol followed. The prototype software was re-coded in C++/OpenCV; image processing was accelerated by data and task parallelization with Message Passaging Interface and Intel Threading Building Blocks and an asynchronous non-blocking I/O strategy. Relative to a serial process, metaphase ranking, GVF and DCE are, respectively, 100 and 300-fold faster on an 8-core desktop and 64-core cluster computers. The software was then ported to a 1024-core supercomputer, which processed 200 metaphase images each from 1025 specimens in 1.4 h. (authors)

  9. Biodosimetry of heavy ions by interphase chromosome painting

    Science.gov (United States)

    Durante, M.; Kawata, T.; Nakano, T.; Yamada, S.; Tsujii, H.

    1998-11-01

    We report measurements of chromosomal aberrations in peripheral blood lymphocytes from cancer patients undergoing radiotherapy treatment. Patients with cervix or esophageal cancer were treated with 10 MV X-rays produced at a LINAC accelerator, or high-energy carbon ions produced at the HIMAC accelerator at the National Institute for Radiological Sciences (NIRS) in Chiba. Blood samples were obtained before, during, and after the radiation treatment. Chromosomes were prematurely condensed by incubation in calyculin A. Aberrations in chromosomes 2 and 4 were scored after fluorescence in situ hybridization with whole-chromosome probes. Pre-treatment samples were exposed in vitro to X-rays, individual dose-response curves for the induction of chromosomal aberrations were determined, and used as calibration curves to calculate the effective whole-body dose absorbed during the treatment. This calculated dose, based on the calibration curve relative to the induction of reciprocal exchanges, has a sharp increase after the first few fractions of the treatment, then saturates at high doses. Although carbon ions are 2-3 times more effective than X-rays in tumor sterilization, the effective dose was similar to that of X-ray treatment. However, the frequency of complex-type chromosomal exchanges was much higher for patients treated with carbon ions than X-ray.

  10. Automating dicentric chromosome detection from cytogenetic biodosimetry data.

    Science.gov (United States)

    Rogan, Peter K; Li, Yanxin; Wickramasinghe, Asanka; Subasinghe, Akila; Caminsky, Natasha; Khan, Wahab; Samarabandu, Jagath; Wilkins, Ruth; Flegal, Farrah; Knoll, Joan H

    2014-06-01

    We present a prototype software system with sufficient capacity and speed to estimate radiation exposures in a mass casualty event by counting dicentric chromosomes (DCs) in metaphase cells from many individuals. Top-ranked metaphase cell images are segmented by classifying and defining chromosomes with an active contour gradient vector field (GVF) and by determining centromere locations along the centreline. The centreline is extracted by discrete curve evolution (DCE) skeleton branch pruning and curve interpolation. Centromere detection minimises the global width and DAPI-staining intensity profiles along the centreline. A second centromere is identified by reapplying this procedure after masking the first. Dicentrics can be identified from features that capture width and intensity profile characteristics as well as local shape features of the object contour at candidate pixel locations. The correct location of the centromere is also refined in chromosomes with sister chromatid separation. The overall algorithm has both high sensitivity (85 %) and specificity (94 %). Results are independent of the shape and structure of chromosomes in different cells, or the laboratory preparation protocol followed. The prototype software was recoded in C++/OpenCV; image processing was accelerated by data and task parallelisation with Message Passaging Interface and Intel Threading Building Blocks and an asynchronous non-blocking I/O strategy. Relative to a serial process, metaphase ranking, GVF and DCE are, respectively, 100 and 300-fold faster on an 8-core desktop and 64-core cluster computers. The software was then ported to a 1024-core supercomputer, which processed 200 metaphase images each from 1025 specimens in 1.4 h. PMID:24757176

  11. HEMODOSE: A Set of Multi-parameter Biodosimetry Tools

    Science.gov (United States)

    Hu, Shaowen; Blakely, William F.; Cucinotta, Francis A.

    2014-01-01

    After the events of September 11, 2001 and recent events at the Fukushima reactors in Japan, there is an increasing concern of the occurrence of nuclear and radiological terrorism or accidents that may result in large casualty in densely populated areas. To guide medical personnel in their clinical decisions for effective medical management and treatment of the exposed individuals, biological markers are usually applied to examine the radiation induced changes at different biological levels. Among these the peripheral blood cell counts are widely used to assess the extent of radiation induced injury. This is due to the fact that hematopoietic system is the most vulnerable part of the human body to radiation damage. Particularly, the lymphocyte, granulocyte, and platelet cells are the most radiosensitive of the blood elements, and monitoring their changes after exposure is regarded as the most practical and best laboratory test to estimate radiation dose. The HEMODOSE web tools are built upon solid physiological and pathophysiological understanding of mammalian hematopoietic systems, and rigorous coarse-grained biomathematical modeling and validation. Using single or serial granulocyte, lymphocyte, leukocyte, or platelet counts after exposure, these tools can estimate absorbed doses of adult victims very rapidly and accurately. Some patient data in historical accidents are utilized as examples to demonstrate the capabilities of these tools as a rapid point-of-care diagnostic or centralized high-throughput assay system in a large scale radiological disaster scenario. Unlike previous dose prediction algorithms, the HEMODOSE web tools establish robust correlations between the absorbed doses and victim's various types of blood cell counts not only in the early time window (1 or 2 days), but also in very late phase (up to 4 weeks) after exposure

  12. Fish cytogenetics and the future of radiation biodosimetry

    International Nuclear Information System (INIS)

    Fluorescence in situ hybridisation with whole chromosome paints has greatly facilitated the analysis of structural chromosome aberrations and has led to translocations replacing dicentrics as the aberration of choice for many applications. Major challenges remain if we are to go from translocations to an understanding of the health consequences of radiation exposure. Yet to be surmounted are the roles of individual susceptibility, time since exposure, and the effects of subjects' age. Accomplishing these objectives will require automation, reduced costs, improved calibration, and extensive use of baseline samples. (author)

  13. Alzheimer's Project

    Medline Plus

    Full Text Available ... state Home > News & Events > Upcoming Events > HBO Alzheimer’s Project In the News Walk to End Alzheimer's Upcoming ... Disease Awareness Month World Alzheimer's Month HBO Alzheimer’s Project MAKE A DONATION Your gift will help us ...

  14. Freedom Project

    Directory of Open Access Journals (Sweden)

    Alejandra Suarez

    2014-02-01

    Full Text Available Freedom Project trains prisoners in nonviolent communication and meditation. Two complementary studies of its effects are reported in this article. The first study is correlational; we found decreased recidivism rates among prisoners trained by Freedom Project compared with recidivism rates in Washington state. The second study compared trained prisoners with a matched-pair control group and found improvement in self-reported anger, self-compassion, and certain forms of mindfulness among the trained group. Ratings of role-plays simulating difficult interactions show increased social skills among the group trained by Freedom Project than in the matched controls.

  15. TIARA project

    Science.gov (United States)

    Malecki, P.

    2013-10-01

    The aim of the Test Infrastructure and Accelerator Research Area - the TIARA project[1] is to consolidate and support the European R&D program in the field of physics and techniques of particle accelerators. This project, partially funded by the European Commission, groups 11 participants from 8 European countries, including Poland. Its present, threeyear (2011-2013) preparatory phase (PP) is shortly described in this paper. The project is divided into 9 work packages (WP). We will concentrate on four of them dedicated to governance, R&D infrastructures, joint R&D programming, and education and training, in which Polish participants are actively involved.

  16. Alzheimer's Project

    Medline Plus

    Full Text Available ... Alzheimer's Gala A Night at Sardi's Alzheimer's Disease Awareness Month World Alzheimer's Month HBO Alzheimer’s ... HBO's "THE ALZHEIMER'S PROJECT" takes a look at the faces behind the disease - and the forces leading us ...

  17. Alzheimer's Project

    Medline Plus

    Full Text Available ... about the films on our message board . Watch films free online now "The Memory Loss Tapes" (85 ... ALZHEIMER'S PROJECT" is a presentation of HBO Documentary Films and the National Institute on Aging at the ...

  18. Alzheimer's Project

    Medline Plus

    Full Text Available ... disease has on those with Alzheimer's and their families. September 14, 2009 "The Alzheimer's Project" wins two ... way Americans thinks about Alzheimer's disease. Tell your family and friends. Post info on your Web site . ...

  19. Alzheimer's Project

    Medline Plus

    Full Text Available ... 272.3900 Find your chapter: search by state Home > News & Events > Upcoming Events > HBO Alzheimer’s Project In the News Walk to End Alzheimer's Upcoming Events AAIC Advocacy Forum Rita ...

  20. Project Reptile!

    Science.gov (United States)

    Diffily, Deborah

    2001-01-01

    Integrating curriculum is important in helping children make connections within and among areas. Presents a class project for kindergarten children which came out of the students' interests and desire to build a reptile exhibit. (ASK)

  1. Alzheimer's Project

    Medline Plus

    Full Text Available ... your family and friends. Post info on your Web site . Become an Alzheimer's champion. Help support vital research and services. "THE ALZHEIMER'S PROJECT" is a presentation of HBO ...

  2. Alzheimer's Project

    Medline Plus

    Full Text Available ... our nation and drive concerned citizens to take action. Here are three ways you can help us change the way ... vital research and services. "THE ALZHEIMER'S PROJECT" is a presentation ...

  3. Alzheimer's Project

    Medline Plus

    Full Text Available ... and the effects this debilitating and fatal disease has on those with Alzheimer's and their families. September ... Alzheimer's care, support and research, the Alzheimer's Association has been an active partner in "THE ALZHEIMER'S PROJECT," ...

  4. Intending Projects

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Project name:Jintan tire production base project (the first-phase project) Construction site:Jintan Economic Development Zone, Jiangsu Province Construction unit:Zhongce Rubber (Jintan) Co., Ltd. Total investment:RMB 2.42 billion yuan Project description:It is planned to cover an area of 3,000 mu. In the first phase, it will cover an area of 520.43 mu with designed staff of 4,500 people. It will mix 150,000 tons of rubber and produce 10 million u- nits of high-performance semi-steel-wire saloon car and light truck radial tires, 500,000 units of OTR tires and 100,000 tons of carbon black per year.

  5. Alzheimer's Project

    Medline Plus

    Full Text Available ... 14, 2009 "The Alzheimer's Project" wins two Creative Arts Emmys Two installments of the multi-part HBO ... from the Alzheimer's Association and others, won Creative Arts Emmy awards. "The Memory Loss Tapes" was honored ...

  6. Radiochemistry Project

    International Nuclear Information System (INIS)

    Researches carried out in the 'Radiochemistry Project' of the Agricultural Nuclear Energy Center, Piracicaba, Sao Paulo State, Brazil, are described. Such researches comprise: dosimetry and radiological protection; development of techniques and methods of chemical analysis and radiochemistry. (M.A.)

  7. Project Management

    DEFF Research Database (Denmark)

    Kampf, Constance

    2009-01-01

    In this video Associate Professor Constance Kampf talks about the importance project management. Not only as a tool in implementation, but also as a way of thinking, and as something that needs to be considered from idea conception......In this video Associate Professor Constance Kampf talks about the importance project management. Not only as a tool in implementation, but also as a way of thinking, and as something that needs to be considered from idea conception...

  8. Project Reconstruct.

    Science.gov (United States)

    Helisek, Harriet; Pratt, Donald

    1994-01-01

    Presents a project in which students monitor their use of trash, input and analyze information via a database and computerized graphs, and "reconstruct" extinct or endangered animals from recyclable materials. The activity was done with second-grade students over a period of three to four weeks. (PR)

  9. Alzheimer's Project

    Medline Plus

    Full Text Available ... 2" (70 minutes) Be a part of something big. HBO's "THE ALZHEIMER'S PROJECT" will expose the Alzheimer's ... show(); jQuery('#TRByZip').html(teamRaisersListHTML); teamRaisersListHTML = ''; } } else { if (data && data.getTeamraisersResponse) { var teamraisers = luminateExtend.utils.ensureArray(data. ...

  10. Project Narrative

    Energy Technology Data Exchange (ETDEWEB)

    Driscoll, Mary C. [St. Bonaventure University, St Bonaventure, NY(United States)

    2012-07-12

    The Project Narrative describes how the funds from the DOE grant were used to purchase equipment for the biology, chemistry, physics and mathematics departments. The Narrative also describes how the equipment is being used. There is also a list of the positive outcomes as a result of having the equipment that was purchased with the DOE grant.

  11. Project Avatar

    DEFF Research Database (Denmark)

    Juhlin, Jonas Alastair

    'Project Avatar' tager udgangspunkt i den efterretningsdisciplin, der kaldes Open Source Intelligence og indebærer al den information, som ligger frit tilgængeligt i åbne kilder. Med udbredelsen af sociale medier åbners der op for helt nye typer af informationskilder. Spørgsmålet er; hvor nyttig er...

  12. Project Baltia

    Index Scriptorium Estoniae

    2007-01-01

    Uus arhitektuuriajakiri "Project Baltia" tutvustab Baltimaade, Soome ja Peterburi regiooni arhitektuuri, linnaehitust ja disaini. Ilmub neli korda aastas inglise- ja venekeelsena. Väljaandja: kirjastus Balticum Peterburis koostöös Amsterdami ja Moskva kirjastusega A-Fond. Peatoimetaja Vladimir Frolov

  13. Alzheimer's Project

    Medline Plus

    Full Text Available ... Chicago National Alzheimer's Gala A Night at Sardi's Alzheimer's Disease Awareness Month World Alzheimer's Month HBO Alzheimer’s Project ... help us change the way Americans thinks about Alzheimer's disease. Tell your family and friends. Post info on ...

  14. Alzheimer's Project

    Medline Plus

    Full Text Available ... Alzheimer's Gala A Night at Sardi's Alzheimer's Disease Awareness Month World Alzheimer's Month HBO Alzheimer’s Project MAKE ... for kids Learn how Maria Shriver is raising awareness '; jQuery('#luminateApi').hide(); jQuery('#otherLinks').show(); jQuery('#TRByZip'). ...

  15. LDRD Final Report for''Tactical Laser Weapons for Defense'' SI (Tracking Code 01-SI-011)

    Energy Technology Data Exchange (ETDEWEB)

    Beach, R; Zapata, L

    2002-01-30

    The focus of this project was a convincing demonstration of two new technological approaches to high beam quality; high average power solid-state laser systems that would be of interest for tactical laser weapon applications. Two pathways had been identified to such systems that built on existing thin disk and fiber laser technologies. This SI was used as seed funding to further develop and vet these ideas. Significantly, the LLNL specific enhancements to these proposed technology paths were specifically addressed for devising systems scaleable to the 100 kW average power level. In the course of performing this work we have established an intellectual property base that protects and distinguishes us from other competitive approaches to the same end.

  16. A dynamically-coupled groundwater, land surface and regional climate model to predict seasonal watershed flow and groundwater response, FINAL LDRD REPORT.

    Energy Technology Data Exchange (ETDEWEB)

    Maxwell, R; Kollet, S; Chow, F; Granvold, P; Duan, Q

    2007-02-23

    This final report is organized in four sections. Section 1 is the project summary (below), Section 2 is a submitted manuscript that describes the offline, or spinup simulations in detail, Section 3 is also a submitted manuscript that describes the online, or fully-coupled simulations in detail and Section 3, which is report that describes work done via a subcontract with UC Berkeley. The goal of this project was to develop and apply a coupled regional climate, land-surface, groundwater flow model as a means to further understand important mass and energy couplings between regional climate, the land surface, and groundwater. The project involved coupling three distinct submodels that are traditionally used independently with abstracted and potentially oversimplified (inter-model) boundary conditions. This coupled model lead to (1) an improved understanding of the sensitivity and importance of coupled physical processes from the subsurface to the atmosphere; (2) a new tool for predicting hydrologic conditions (rainfall, temperature, snowfall, snowmelt, runoff, infiltration and groundwater flow) at the watershed scale over a range of timeframes; (3) a simulation of hydrologic response of a characteristic watershed that will provide insight into the certainty of hydrologic forecasting, dominance and sensitivity of groundwater dynamics on land-surface fluxes; and (4) a more realistic model representation of weather predictions, precipitation and temperature, at the regional scale. Regional climate models are typically used for the simulation of weather, precipitation and temperature behavior over 10-1000 km domains for weather or climate prediction purposes, and are typically driven by boundary conditions derived from global climate models (GCMs), observations or both. The land or ocean surface typically represents a bottom boundary condition of these models, where important mass (water) and energy fluxes are approximated. The viability and influence of these

  17. Projective geometry and projective metrics

    CERN Document Server

    Busemann, Herbert

    2005-01-01

    The basic results and methods of projective and non-Euclidean geometry are indispensable for the geometer, and this book--different in content, methods, and point of view from traditional texts--attempts to emphasize that fact. Results of special theorems are discussed in detail only when they are needed to develop a feeling for the subject or when they illustrate a general method. On the other hand, an unusual amount of space is devoted to the discussion of the fundamental concepts of distance, motion, area, and perpendicularity.Topics include the projective plane, polarities and conic sectio

  18. Hydropower Projects

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-04-02

    The Water Power Program helps industry harness this renewable, emissions-free resource to generate environmentally sustainable and cost-effective electricity. Through support for public, private, and nonprofit efforts, the Water Power Program promotes the development, demonstration, and deployment of advanced hydropower devices and pumped storage hydropower applications. These technologies help capture energy stored by diversionary structures, increase the efficiency of hydroelectric generation, and use excess grid energy to replenish storage reserves for use during periods of peak electricity demand. In addition, the Water Power Program works to assess the potential extractable energy from domestic water resources to assist industry and government in planning for our nation’s energy future. From FY 2008 to FY 2014, DOE’s Water Power Program announced awards totaling approximately $62.5 million to 33 projects focused on hydropower. Table 1 provides a brief description of these projects.

  19. PARTNER Project

    CERN Multimedia

    Ballantine, A; Dixon-Altaber, H; Dosanjh, M; Kuchina, L

    2011-01-01

    Hadrontherapy uses particle beams to treat tumours located near critical organs and tumours that respond poorly to conventional radiation therapy. It has become evident that there is an emerging need for reinforcing research in hadrontherapy and it is essential to train professionals in this rapidly developing field. PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network. The project offers research and training opportunities to 25 young biologists, engineers, physicians and physicists and is allowing them to actively develop modern techniques for treating cancer in close collaboration with leading European Institutions. For this purpose PARTNER relies on cutting edge research and technology development, ef...

  20. Project Phaseolus

    International Nuclear Information System (INIS)

    Research carried out through the Phaseolus Project of the 'Centro de Energia Nuclear na Agricultura' (CENA) Piracicaba, Sao Paulo State, Brazil, is described. It comprises the following subject s: plant breeding; nitrogen fixation; tissue cultures; proteins; photosynthetic efficiency; soil-plant interactions; electron microscopy of the golden mosaic virus; pest control; production of 15N-enriched ammonium sulfate, and determination of elements in the beans plant. (M.A.)

  1. Teseus project

    OpenAIRE

    Petersen, Simone; Marsà, Quim; Chen, Kuan Wei; Arriaga, Lorena; Aleixendri, Joan Josep

    2015-01-01

    This project, TESEUS, is being carried out within the umbrella of the ongoing Urban Node study and focuses on the development of a computational system capable of handling a huge amount of data received from urban nodes in a smart city. There are already existing computer systems with computational power capable of handling the amount of data a smart city requires. Although these computers may provide all the power required to maintain and manage a smart city, they can always b...

  2. Projection Methods

    DEFF Research Database (Denmark)

    Wagner, Falko Jens; Poulsen, Mikael Zebbelin

    1999-01-01

    When trying to solve a DAE problem of high index with more traditional methods, it often causes instability in some of the variables, and finally leads to breakdown of convergence and integration of the solution. This is nicely shown in [ESF98, p. 152 ff.].This chapter will introduce projection...... methods as a way of handling these special problems. It is assumed that we have methods for solving normal ODE systems and index-1 systems....

  3. SUPERSITE PROJECT

    Directory of Open Access Journals (Sweden)

    Silvia Ferrari

    2010-04-01

    Full Text Available The project is focused on a detailed study of some chemical, physical and toxicological parameters and on health, epidemiological and environmental assessment by interpretative models, in the atmosphere of Emilia-Romagna (Italy. The project rises from the necessity to improve  knowledge about environmental and health aspects of fine and ultrafine particles, in primary and secondary components, in the atmosphere. The project, structured in 7 workpackages, is organized in two measurement programmes: the routine one that has a mainly daily time resolution, and the intensive one with high time resolution and a higher chemical speciation than the routine one. The sampling sites are five: three in urban areas (Bologna, Parma and Rimini, one in a rural area (San Pietro Capofiume and one in a remote area (Monte Cimone. Parallel to outdoor studies, a workpackage  is planned for indoor studies and chemical composition analysis with the  outdoor/indoor ratio for characterizing indoor human exposure to outdoor pollution.

  4. LDRD final report on synthesis of shape-and size-controlled platinum and platinum alloy nanostructures on carbon with improved durability.

    Energy Technology Data Exchange (ETDEWEB)

    Shelnutt, John Allen; Garcia, Robert M.; Song, Yujiang; Moreno, Andres M.; Stanis, Ronald J.

    2008-10-01

    This project is aimed to gain added durability by supporting ripening-resistant dendritic platinum and/or platinum-based alloy nanostructures on carbon. We have developed a new synthetic approach suitable for directly supporting dendritic nanostructures on VXC-72 carbon black (CB), single-walled carbon nanotubes (SWCNTs), and multi-walled carbon nanotubes (MWCNTs). The key of the synthesis is to creating a unique supporting/confining reaction environment by incorporating carbon within lipid bilayer relying on a hydrophobic-hydrophobic interaction. In order to realize size uniformity control over the supported dendritic nanostructures, a fast photocatalytic seeding method based on tin(IV) porphyrins (SnP) developed at Sandia was applied to the synthesis by using SnP-containing liposomes under tungsten light irradiation. For concept approval, one created dendritic platinum nanostructure supported on CB was fabricated into membrane electrode assemblies (MEAs) for durability examination via potential cycling. It appears that carbon supporting is essentially beneficial to an enhanced durability according to our preliminary results.

  5. Coloss project

    International Nuclear Information System (INIS)

    The COLOSS project was a shared-cost action, co-ordinated by IRSN within the Euratom Research Framework Programme 1998-2002. Started in February 2000, the project lasted three years. The work-programme performed by 19 partners was shaped around complementary activities aimed at improving severe accident codes. Unresolved risk-relevant issues regarding H2 production, melt generation and the source term were studied, through a large number of experiments such as a) dissolution of fresh and high burn-up UO2 and MOX by molten Zircaloy, b) simultaneous dissolution of UO2 and ZrO2 by molten Zircaloy, c) oxidation of U-O-Zr mixtures by steam, d) degradation-oxidation of B4C control rods. Significant results have been produced from separate-effects, semi-global and large-scale tests on COLOSS topics. Break-through were achieved on some issues. Nevertheless, more data are needed for consolidation of the modelling on burn-up effects on UO2 and MOX dissolution and on oxidation of U-O-Zr and B4C-metal mixtures. There was experimental evidence that the oxidation of these mixtures can contribute significantly to the large H2 production observed during the reflooding of degraded cores under severe accident conditions. Based on the experimental results obtained on the COLOSS topics, corresponding models were developed and were successfully implemented in several severe accident codes. Upgraded codes were then used for plant calculations to evaluate the consequences of new models on key severe accident sequences occurring in different plants designs involving B4C control rods (EPR, BWR, VVER- 1000) as well as in the TMI-2 accident. The large series of plant calculations involved sensitivity studies and code benchmarks. Main severe accident codes in use in the EU for safety studies were used such as ICARE/CATHARE, SCDAP/RELAP5, ASTEC, MELCOR and MAAP4. This activity enabled: a) the assessment of codes to calculate core degradation, b) the identification of main uncertainties and

  6. FLOAT Project

    DEFF Research Database (Denmark)

    Sørensen, Eigil V.; Aarup, Bendt

    The objective of the FLOAT project is to study the reliability of high-performance fibre-reinforced concrete, also known as Compact Reinforced Composite (CRC), for the floats of wave energy converters. In order to reach a commercial breakthrough, wave energy converters need to achieve a lower price...... of energy produced, comparable to prices currently obtained from offshore wind power, and this can be done by the use of more suitable materials. The flotation device is a key part of converters, as it accounts for a considerable share of initial investment, up to 27% depending on the converter. CRC floats...

  7. Project Lyman

    OpenAIRE

    McCandliss, Stephan R.; Kruk, Jeffrey W.; Blair, William P.; Kaiser, Mary Elizabeth; Feldman, Paul D.; Meurer, Gerhardt R.; Dixon, William V.; Sahnow, David J.; Neufeld, David A.; Lupu, Roxana E.; Fleming, Brian; Smee, Stephen A.; Andersson, B. G.; Moseley, Samuel H.; Kutyrev, Alexander S.

    2008-01-01

    We explore the design of a space mission, Project Lyman, which has the goal of quantifying the ionization history of the universe from the present epoch to a redshift of z ~ 3. Observations from WMAP and SDSS show that before a redshift of z >~ 6 the first collapsed objects, possibly dwarf galaxies, emitted Lyman continuum (LyC) radiation shortward of 912 A, reionizing most of the universe. How LyC escapes from galactic environments, whether it induces positive or negative feedback on the loc...

  8. Project Success in IT Project Management

    OpenAIRE

    Siddiqui, Farhan Ahmed

    2010-01-01

    The rate of failed and challenged Information Technology (IT) projects is too high according to the CHAOS Studies by the Standish Group and the literature on project management (Standish Group, 2008). The CHAOS Studies define project success as meeting the triple constraints of scope, time, and cost. The criteria for project success need to be agreed by all parties before the start of the project and constantly reviewed as the project progresses. Assessing critical success factors is another ...

  9. FLORAM project

    Energy Technology Data Exchange (ETDEWEB)

    Zulauf, W.E. [Sao Paolos Environmental Secretariat, Sao Paolo (Brazil); Goelho, A.S.R. [Riocell, S.A. (Brazil); Saber, A. [IEA-Instituto de Estudos Avancados (Brazil)] [and others

    1995-12-31

    The project FLORAM was formulated at the `Institute for Advanced Studies` of the University of Sao Paulo. It aims at decreasing the level of carbon dioxide in the atmosphere and thus curbing the green-house effect by way of a huge effort of forestation and reforestation. The resulting forests when the trees mature, will be responsible for the absorption of about 6 billion tons of excess carbon. It represents 5 % of the total amount of CO{sub 2} which is in excess in the earth`s atmosphere and represents 5 % of the available continental surfaces which can be forested as well. Therefore, if similar projects are implemented throughout the world, in theory all the exceeding CO{sub 2}, responsible for the `greenhouse effect`, (27 % or 115 billion tons of carbon) would be absorbed. Regarding this fact, there would be a 400 million hectar increase of growing forests. FLORAM in Brazil aims to plant 20.000.000 ha in 2 years at a cost of 20 billion dollars. If it reaches its goals that will mean that Brazil will have reforested an area almost half as big as France. (author)

  10. PORTNUS Project

    Energy Technology Data Exchange (ETDEWEB)

    Loyal, Rebecca E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-07-14

    The objective of the Portunus Project is to create large, automated offshore ports that will the pace and scale of international trade. Additionally, these ports would increase the number of U.S. domestic trade vessels needed, as the imported goods would need to be transported from these offshore platforms to land-based ports such as Boston, Los Angeles, and Newark. Currently, domestic trade in the United States can only be conducted by vessels that abide by the Merchant Marine Act of 1920 – also referred to as the Jones Act. The Jones Act stipulates that vessels involved in domestic trade must be U.S. owned, U.S. built, and manned by a crew made up of U.S. citizens. The Portunus Project would increase the number of Jones Act vessels needed, which raises an interesting economic concern. Are Jones Act ships more expensive to operate than foreign vessels? Would it be more economically efficient to modify the Jones Act and allow vessels manned by foreign crews to engage in U.S. domestic trade? While opposition to altering the Jones Act is strong, it is important to consider the possibility that ship-owners who employ foreign crews will lobby for the chance to enter a growing domestic trade market. Their success would mean potential job loss for thousands of Americans currently employed in maritime trade.

  11. SISCAL project

    Science.gov (United States)

    Santer, Richard P.; Fell, Frank

    2003-05-01

    The first "ocean colour" sensor, Coastal Zone Color Scanner (CZCS), was launched in 1978. Oceanographers learnt a lot from CZCS but it remained a purely scientific sensor. In recent years, a new generation of satellite-borne earth observation (EO) instruments has been brought into space. These instruments combine high spectral and spatial resolution with revisiting rates of the order of one per day. More instruments with further increased spatial, spectral and temporal resolution will be available within the next years. In the meantime, evaluation procedures taking advantage of the capabilities of the new instruments were derived, allowing the retrieval of ecologically important parameters with higher accuracy than before. Space agencies are now able to collect and to process satellite data in real time and to disseminate them via the Internet. It is therefore meanwhile possible to envisage using EO operationally. In principle, a significant demand for EO data products on terrestrial or marine ecosystems exists both with public authorities (environmental protection, emergency management, natural resources management, national parks, regional planning, etc) and private companies (tourist industry, insurance companies, water suppliers, etc). However, for a number of reasons, many data products that can be derived from the new instruments and methods have not yet left the scientific community towards public or private end users. It is the intention of the proposed SISCAL (Satellite-based Information System on Coastal Areas and Lakes) project to contribute to the closure of the existing gap between space agencies and research institutions on one side and end users on the other side. To do so, we intend to create a data processor that automatically derives and subsequently delivers over the Internet, in Near-Real-Time (NRT), a number of data products tailored to individual end user needs. The data products will be generated using a Geographical Information System (GIS

  12. PROJECT TEAM MOTIVATION IN PROJECT REALISATION

    OpenAIRE

    Perica Jankoviæ

    2014-01-01

    Managing a project team is an everyday activity when managing a project realization. In order to accomplish efficiency at work on a project, it is necessary for all the participants in the project to be motivated and interested, focused on accomplishing the project. To the end of providing greater motivation of the project team for the realization of the project, the project manager should be very well acquainted with the needs and motives of the people he/she is managing and should find the ...

  13. 2015 Fermilab Laboratory Directed Research & Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-26

    The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple of years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.

  14. ENVISION Project

    CERN Multimedia

    Ballantine, A; Dixon-Altaber, H; Dosanjh, M; Kuchina, L

    2011-01-01

    Hadrontherapy is a highly advanced technique of cancer radiotherapy that uses beams of charged particles (ions) to destroy tumour cells. While conventional X-rays traverse the human body depositing radiation as they pass through, ions deliver most of their energy at one point. Hadrontherapy is most advantageous once the position of the tumour is accurately known, so that healthy tissues can be protected. Accurate positioning is a crucial challenge for targeting moving organs, as in lung cancer, and for adapting the irradiation as the tumour shrinks with treatment. Therefore, quality assurance becomes one of the most relevant issues for an effective outcome of the cancer treatment. In order to improve the quality assurance tools for hadrontherapy, the European Commission is funding ENVISION, a 4-year project that aims at developing solutions for: real-• time non invasive monitoring • quantitative imaging • precise determination of delivered dose • fast feedback for optimal treatment planning • real-t...

  15. Projective mapping

    DEFF Research Database (Denmark)

    Dehlholm, Christian; Brockhoff, Per B.; Bredie, Wender Laurentius Petrus

    2012-01-01

    the applied framework, semantic restrictions, the choice of type of assessors and the validation of product separations. The applied framework concerns the response surface as presented to the assessor in different shapes, e.g. rectangular, square or round. Semantic restrictions are a part of the assessor...... instructions and influence heavily the product placements and the descriptive vocabulary (Dehlholm et.al., 2012b). The type of assessors performing the method influences results with an extra aspect in Projective Mapping compared to more analytical tests, as the given spontaneous perceptions are much dependent...... on the assessor’s way of thinking. Furthermore, a suggestion for validating product separations is proposed for the case where Multiple Factor Analysis is chosen for data analysis (Dehlholm, Brockhoff & Bredie, 2012a)....

  16. Project: Ultracentrifuges

    International Nuclear Information System (INIS)

    The trans elastic ultracentrifuge of magnetic suspension, is an instrument that arose of an interdisciplinary group directed by the Dr. James Clark Keith where it was projected, designed and built a centrifuge that didn't exist, to be applied in forced diffusion of uranium, like one of the many application fields. The written present, has as purpose to give to know the fundamental physical principles of this technology, its fundamental characteristics of design, the application of this in the separation process of isotopes, as well as the previous studies and essential control parameters in the experimental processes, the same thing that, the most outstanding results and the detection systems used in the confirmation and finally, the carried out potential applications of the principles of the ultracentrifugation technology. (Author)

  17. A Next Generation Digital Counting System For Low-Level Tritium Studies (Project Report)

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-10-03

    Since the early seventies, SRNL has pioneered low-level tritium analysis using various nuclear counting technologies and techniques. Since 1999, SRNL has successfully performed routine low-level tritium analyses with counting systems based on digital signal processor (DSP) modules developed in the late 1990s. Each of these counting systems are complex, unique to SRNL, and fully dedicated to performing routine tritium analyses of low-level environmental samples. It is time to modernize these systems due to a variety of issues including (1) age, (2) lack of direct replacement electronics modules and (3) advances in digital signal processing and computer technology. There has been considerable development in many areas associated with the enterprise of performing low level tritium analyses. The objective of this LDRD project was to design, build, and demonstrate a Next Generation Tritium Counting System (NGTCS), while not disrupting the routine low-level tritium analyses underway in the facility on the legacy counting systems. The work involved (1) developing a test bed for building and testing new counting system hardware that does not interfere with our routine analyses, (2) testing a new counting system based on a modern state of the art DSP module, and (3) evolving the low-level tritium counter design to reflect the state of the science.

  18. Ace Project as a Project Management Tool

    Science.gov (United States)

    Cline, Melinda; Guynes, Carl S.; Simard, Karine

    2010-01-01

    The primary challenge of project management is to achieve the project goals and objectives while adhering to project constraints--usually scope, quality, time and budget. The secondary challenge is to optimize the allocation and integration of resources necessary to meet pre-defined objectives. Project management software provides an active…

  19. Evaluation of Project Achievements in VOMARE -project

    OpenAIRE

    Kokkarinen, Eeva

    2011-01-01

    The purpose of the thesis is to study the achievements of VOMARE –project from the Finnish Lifeboat Institutions perspective. The organisation is a roof organisation for voluntary maritime rescue operation in Finland. The Finnish Lifeboat Institution is a lead partner in VOMARE –project which is EU funded project and the aim of the project is to start voluntary rescue operations in Estonia. The theoretical part of the work is divided into two main categories; project management and planni...

  20. Project Lyman

    CERN Document Server

    McCandliss, Stephan R; Blair, William P; Kaiser, Mary Elizabeth; Feldman, Paul D; Meurer, Gerhardt R; Dixon, William V; Sahnow, David J; Neufeld, David A; Lupu, Roxana E; Fleming, Brian; Smee, Stephen A; Andersson, B G; Moseley, Samuel H; Kutyrev, Alexander S; Li, Mary J; Sonneborn, George; Siegmund, Oswald H W; Vallerga, John V; Welsh, Barry Y; Stiavelli, Massimo; Windhorst, Rogier A; Shapley, Alice E

    2008-01-01

    We explore the design of a space mission, Project Lyman, which has the goal of quantifying the ionization history of the universe from the present epoch to a redshift of z ~ 3. Observations from WMAP and SDSS show that before a redshift of z >~ 6 the first collapsed objects, possibly dwarf galaxies, emitted Lyman continuum (LyC) radiation shortward of 912 A, reionizing most of the universe. How LyC escapes from galactic environments, whether it induces positive or negative feedback on the local and global collapse of structures, and the role played by clumping, molecules, metallicity and dust are major unanswered theoretical questions, requiring observational constraint. Numerous intervening Lyman limit systems, which frustrate the detection of LyC from high z objects, thin below z ~ 3 where there are a few objects with apparently very high fesc. At low z there are only controversial detections and a handful of upper limits. A wide-field multi-object spectroscopic survey with moderate spectral and spatial res...

  1. Project management

    OpenAIRE

    Se, Ngoc

    2010-01-01

    Η παρούσα εργασία ασχολείται με τη διαμόρφωση μίας πλήρους και συνεκτικής πρότασης σχετικά με την ανάπτυξη ενός Μεταπτυχιακού Προγράμματος Σπουδών (ΜΠΣ) στη Διοίκηση Έργων (Project Management), λαμβάνοντας υπόψη τα εξής: το σύνολο των διεθνώς αποδεκτών θεμάτων που απαρτίζουν το λεγόμενο κορμό γνώσης (body of knowledge) στη διοίκηση έργων, τις βέλτιστες διεθνείς πρακτικές όπως έχουν καταγραφεί από αναζήτηση, διερεύνηση και ανάλυση αντίστοιχων διεθνώς ΜΠΣ, και αναγκαιότητα της αγορά...

  2. Storytelling in Projects

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas; Andersen, Peter Bøgh

    2006-01-01

    Plans and stories are two different ways of communicating about projects. Project plans are formalized descriptions, primarily supporting coordination. Project stories are accounts whose primary function is emotional appeal. Project stories influence the projects’ chances of success. Therefore pr...... the possibilities of telling favorable stories may have repercussions on the project planning.......Plans and stories are two different ways of communicating about projects. Project plans are formalized descriptions, primarily supporting coordination. Project stories are accounts whose primary function is emotional appeal. Project stories influence the projects’ chances of success. Therefore...... project managers should not only be concerned with project plans, but also with project stories. In this paper we explore some basic principles for transforming project plans into appealing stories. We discuss what may happen to stories once they are released into public space. And we illustrate how...

  3. Managing projects using a project management approach

    Directory of Open Access Journals (Sweden)

    Marko D. Andrejić

    2011-04-01

    Full Text Available Modern management theory treats all complex tasks and duties like projects and make these projects possible to be managed by a particular organizational-management concept in order to achieve a goal effectively. A large number of jobs and tasks performed in the system of defense or for defense purposes have the characteristics of projects. Project management is both a skill and a science of monitoring human, material, financial, energy and other resources to achieve required objectives within the given limits: deadlines, time, budget, possibility of realization and the satisfaction of the interests of all project participants. Project management is a traditional area of applied (or functional management focused on managing complex and uncertain situations with defined goals. Introduction In conditions of rapid change and high uncertainty, only adaptive organizations survive, i. e. those that are able not only to react quickly to changes but also to proactively take advantage of changes. Development of project management The biggest influence on the development of the area had complex jobs within the engineering profession. In parallel with the traditional approach new approaches began to develop, while the traditional one still remained in use. Contrary to the traditional engineering approach, a dynamic model first developed in order to respond to demands for greater control of costs. Project management Project management is a skill and knowledge of human and material resources to achieve set objectives within prescribed limits: deadlines, time, budget, possibility of realization, and the satisfaction of all participants in the project. In order to realize a project effectively, it is necessary to manage it rationally. Planning and project management A project plan is a document that allows all team members insight on where to go, when to start and when to arrive, what is necessary to be done in order to achieve the project objectives and what

  4. Project Planning and Management

    NARCIS (Netherlands)

    Weide, van der A.; Beulens, A.J.M.; Dijk, van S.

    2003-01-01

    Project Planning and Management helps prepare the reader to contribute confidently and effectively when working on projects or in managing project teams. This books concentrates on the output of a project as well as the whole process. It is written for projects in the areas of IT and knowledge manag

  5. LDRD report: Smoke effects on electrical equipment

    Energy Technology Data Exchange (ETDEWEB)

    TANAKA,TINA J.; BAYNES JR.,EDWARD E.; NOWLEN,STEVEN P.; BROCKMANN,JOHN E.; GRITZO,LOUIS A.; SHADDIX,CHRISTOPHER R.

    2000-03-01

    Smoke is known to cause electrical equipment failure, but the likelihood of immediate failure during a fire is unknown. Traditional failure assessment techniques measure the density of ionic contaminants deposited on surfaces to determine the need for cleaning or replacement of electronic equipment exposed to smoke. Such techniques focus on long-term effects, such as corrosion, but do not address the immediate effects of the fire. This document reports the results of tests on the immediate effects of smoke on electronic equipment. Various circuits and components were exposed to smoke from different fields in a static smoke exposure chamber and were monitored throughout the exposure. Electrically, the loss of insulation resistance was the most important change caused by smoke. For direct current circuits, soot collected on high-voltage surfaces sometimes formed semi-conductive soot bridges that shorted the circuit. For high voltage alternating current circuits, the smoke also tended to increase the likelihood of arcing, but did not accumulate on the surfaces. Static random access memory chips failed for high levels of smoke, but hard disk drives did not. High humidity increased the conductive properties of the smoke. The conductivity does not increase linearly with smoke density as first proposed; however, it does increase with quantity. The data can be used to give a rough estimate of the amount of smoke that will cause failures in CMOS memory chips, dc and ac circuits. Comparisons of this data to other fire tests can be made through the optical and mass density measurements of the smoke.

  6. Desalination utilizing clathrate hydrates (LDRD final report).

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, Blake Alexander; Bradshaw, Robert W.; Dedrick, Daniel E.; Cygan, Randall Timothy (Sandia National Laboratories, Albuquerque, NM); Greathouse, Jeffery A. (Sandia National Laboratories, Albuquerque, NM); Majzoub, Eric H. (University of Missouri, Columbia, MO)

    2008-01-01

    Advances are reported in several aspects of clathrate hydrate desalination fundamentals necessary to develop an economical means to produce municipal quantities of potable water from seawater or brackish feedstock. These aspects include the following, (1) advances in defining the most promising systems design based on new types of hydrate guest molecules, (2) selection of optimal multi-phase reactors and separation arrangements, and, (3) applicability of an inert heat exchange fluid to moderate hydrate growth, control the morphology of the solid hydrate material formed, and facilitate separation of hydrate solids from concentrated brine. The rate of R141b hydrate formation was determined and found to depend only on the degree of supercooling. The rate of R141b hydrate formation in the presence of a heat exchange fluid depended on the degree of supercooling according to the same rate equation as pure R141b with secondary dependence on salinity. Experiments demonstrated that a perfluorocarbon heat exchange fluid assisted separation of R141b hydrates from brine. Preliminary experiments using the guest species, difluoromethane, showed that hydrate formation rates were substantial at temperatures up to at least 12 C and demonstrated partial separation of water from brine. We present a detailed molecular picture of the structure and dynamics of R141b guest molecules within water cages, obtained from ab initio calculations, molecular dynamics simulations, and Raman spectroscopy. Density functional theory calculations were used to provide an energetic and molecular orbital description of R141b stability in both large and small cages in a structure II hydrate. Additionally, the hydrate of an isomer, 1,2-dichloro-1-fluoroethane, does not form at ambient conditions because of extensive overlap of electron density between guest and host. Classical molecular dynamics simulations and laboratory trials support the results for the isomer hydrate. Molecular dynamics simulations show that R141b hydrate is stable at temperatures up to 265K, while the isomer hydrate is only stable up to 150K. Despite hydrogen bonding between guest and host, R141b molecules rotated freely within the water cage. The Raman spectrum of R141b in both the pure and hydrate phases was also compared with vibrational analysis from both computational methods. In particular, the frequency of the C-Cl stretch mode (585 cm{sup -1}) undergoes a shift to higher frequency in the hydrate phase. Raman spectra also indicate that this peak undergoes splitting and intensity variation as the temperature is decreased from 4 C to -4 C.

  7. Tools for characterizing biomembranes : final LDRD report.

    Energy Technology Data Exchange (ETDEWEB)

    Alam, Todd Michael; Stevens, Mark; Holland, Gregory P.; McIntyre, Sarah K.

    2007-10-01

    A suite of experimental nuclear magnetic resonance (NMR) spectroscopy tools were developed to investigate lipid structure and dynamics in model membrane systems. By utilizing both multinuclear and multidimensional NMR experiments a range of different intra- and inter-molecular contacts were probed within the membranes. Examples on pure single component lipid membranes and on the canonical raft forming mixture of DOPC/SM/Chol are presented. A unique gel phase pretransition in SM was also identified and characterized using these NMR techniques. In addition molecular dynamics into the hydrogen bonding network unique to sphingomyelin containing membranes were evaluated as a function of temperature, and are discussed.

  8. High-Assurance Software: LDRD Report.

    Energy Technology Data Exchange (ETDEWEB)

    Hulette, Geoffrey Compton

    2014-06-01

    This report summarizes our work on methods for developing high-assurance digital systems. We present an approach for understanding and evaluating trust issues in digital systems, and for us- ing computer-checked proofs as a means for realizing this approach. We describe the theoretical background for programming with proofs based on the Curry-Howard correspondence, connect- ing the field of logic and proof theory to programs. We then describe a series of case studies, intended to demonstrate how this approach might be adopted in practice. In particular, our stud- ies elucidate some of the challenges that arise with this style of certified programming, including induction principles, generic programming, termination requirements, and reasoning over infinite state spaces.

  9. LDRD final report on carbon nanotube composites

    Energy Technology Data Exchange (ETDEWEB)

    Cahill, P.A.; Rand, P.B.

    1997-04-01

    Carbon nanotubes and their composites were examined using computational and experimental techniques in order to modify the mechanical and electrical properties of resins. Single walled nanotubes were the focus of the first year effort; however, sufficient quantities of high purity single walled nanotubes could not be obtained for mechanical property investigations. The unusually high electrical conductivity of composites loaded with <1% of multiwalled nanotubes is useful, and is the focus of continuing, externally funded, research.

  10. Managing projects using a project management approach

    OpenAIRE

    Marko D. Andrejić; Boban D. Đorović; Dragan S. Pamučar

    2011-01-01

    Modern management theory treats all complex tasks and duties like projects and make these projects possible to be managed by a particular organizational-management concept in order to achieve a goal effectively. A large number of jobs and tasks performed in the system of defense or for defense purposes have the characteristics of projects. Project management is both a skill and a science of monitoring human, material, financial, energy and other resources to achieve required objectives within...

  11. Managing Projects for Change: Contextualised Project Management

    Science.gov (United States)

    Tynan, Belinda; Adlington, Rachael; Stewart, Cherry; Vale, Deborah; Sims, Rod; Shanahan, Peter

    2010-01-01

    This paper will detail three projects which focussed on enhancing online learning at a large Australian distance education University within a School of Business, School of Health and School of Education. Each project had special funding and took quite distinctive project management approaches, which reflect the desire to embed innovation and…

  12. From project management to project leadership

    NARCIS (Netherlands)

    F. Braun; M. Avital

    2010-01-01

    It is virtually a truism that good leadership practices can help project managers with attaining the desired project outcome. However, a better understanding of which leadership practices enable project managers to be more effective warrants further investigation. Subsequently, in this study, we inv

  13. Web Project Management

    OpenAIRE

    Suralkar, Sunita; Joshi, Nilambari; Meshram, B. B.

    2013-01-01

    This paper describes about the need for Web project management, fundamentals of project management for web projects: what it is, why projects go wrong, and what's different about web projects. We also discuss Cost Estimation Techniques based on Size Metrics. Though Web project development is similar to traditional software development applications, the special characteristics of Web Application development requires adaption of many software engineering approaches or even development of comple...

  14. Project 2010 For Dummies

    CERN Document Server

    Muir, Nancy C

    2010-01-01

    A friendly reference guide to Microsoft Project, the leading enterprise project management software. As project management software, Microsoft Project allows you to oversee your business activities effectively. You can manage resources, share project info, perform modeling and scenario analysis, and standardize reporting processes. This easy-to-understand guide is completely updated to cover the latest changes and newest enhancements to Project 2010 and shows you how to get Project 2010 to work for you. After an introduction to basic project management concepts, you'll discover the mechanics o

  15. USAID Anticorruption Projects Database

    Data.gov (United States)

    US Agency for International Development — The Anticorruption Projects Database (Database) includes information about USAID projects with anticorruption interventions implemented worldwide between 2007 and...

  16. Project Half Double

    DEFF Research Database (Denmark)

    Ehlers, Michael; Adland, Karoline Thorp; Boston, Nicolai Elborough;

    Project Half Double has a clear mission to succeed in finding a project methodology that can increase the success rate of our projects while increasing the speed at which we generate new ideas and develop new products and services. Chaos and complexity should be seen as a basic condition...... activities carried out within the framework of the projects. The formal part of Project Half Double was initiated in June 2015. We started out by developing, refining and testing the Half Double methodology on seven pilot projects in the first phase of the project, which will end June 2016. The current...... organisations concerning project methodology and beyond. The many learning points from each pilot project show that Project Half Double has left its clear footprint in the pilot organisations, and that the Half Double methodology has evolved and developed very much during Project Half Double phase 1....

  17. Assembling the Project Team.

    Science.gov (United States)

    Mills, Donald B.

    2003-01-01

    Although the approval of a project's design and budget typically rests with the campus governing board, a project team determines the configuration, the cost, and the utility of the completed project. Because of the importance of these decisions, colleges and universities must select project team members carefully. (Author)

  18. The virtual GULLIVER project

    NARCIS (Netherlands)

    Nijholt, A.; Stuk, M.; Zwiers, J.; Trappl, R.

    2002-01-01

    In this paper we discuss our virtual reality project Gulliver. This project is part of a more comprehensive project conceived by two artists, Matjaž Štuk and Alena Hudcovicová, called “Gulliver’s Museum of Living Art”. Our part of the project involves a virtual reality version of Swift’s Gulliver fi

  19. Earth System Science Project

    Science.gov (United States)

    Rutherford, Sandra; Coffman, Margaret

    2004-01-01

    For several decades, science teachers have used bottles for classroom projects designed to teach students about biology. Bottle projects do not have to just focus on biology, however. These projects can also be used to engage students in Earth science topics. This article describes the Earth System Science Project, which was adapted and developed…

  20. Introduction to the Project

    DEFF Research Database (Denmark)

    Kuhn, Johan M.; Malchow-Møller, Nikolaj; Sørensen, Anders

    In this note a short introduction to the project “Employment Effects of Entrepreneurs” is presented. First, we describe the purpose of the project; second, we present the background; third, we briefly describe the three papers that constitute the output of the project, and fourth, we discuss two...... important qualifications for the understanding of the contributions and results established in the project....

  1. Project stakeholder management

    CERN Document Server

    Eskerod, Pernille

    2013-01-01

    Carrying out a project as planned is not a guarantee for success. Projects may fail because project management does not take the requirements, wishes and concerns of stakeholders sufficiently into account. Projects can only be successful though contributions from stakeholders. And in the end, it is the stakeholders that evaluate whether they find that the project is a success. To manage stakeholders effectively, you need to know your stakeholders, their behaviours and attitudes towards the project. In Project Stakeholder Management, the authors give guidance on how to adopt an analytical and s

  2. Modern project-management

    CERN Document Server

    CERN. Geneva

    2003-01-01

    This lecture will focus on the following issues: - The current state of the art in Project Management, especially the integration of Project Management with general management activities, and the integrated view of resources allocation. - Overview of the project life cycle, the phases and the deliverables - Necessity and limits of planning in a research environment - Organizational aspects of the projects the roles of the stakeholders - How to get the resources when they are needed - Risk Management in Projects - Earned value - How to keep a project on track (schedule and budget) - Management of the suppliers - Closing of the project

  3. IT Project Management Metrics

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available Many software and IT projects fail in completing theirs objectives because different causes of which the management of the projects has a high weight. In order to have successfully projects, lessons learned have to be used, historical data to be collected and metrics and indicators have to be computed and used to compare them with past projects and avoid failure to happen. This paper presents some metrics that can be used for the IT project management.

  4. Methodologies of Project Management

    Directory of Open Access Journals (Sweden)

    Wojciech Macek

    2011-07-01

    Full Text Available This paper presents comparison of three most popular project management standardsbelonging to a wider group of models (for example, PMBOK, Prince 2, CMMI, ISO 10006,BS 6079, IPMA Competence Baseline, European Commission Project Cycle ManagementGuidelines. The author discusses methods of project management according to PMBoK,Prince 2 and ISO 10006, some chosen criteria and fields of knowledge, such as generalregulations of standards, project range management, resources management, and processesconnected with risk, systems of project quality management.

  5. Project delivery system (PDS)

    CERN Document Server

    2001-01-01

    As business environments become increasingly competitive, companies seek more comprehensive solutions to the delivery of their projects. "Project Delivery System: Fourth Edition" describes the process-driven project delivery systems which incorporates the best practices from Total Quality and is aligned with the Project Management Institute and ISO Quality Standards is the means by which projects are consistently and efficiently planned, executed and completed to the satisfaction of clients and customers.

  6. Overview about project planning

    OpenAIRE

    Catalin Drob

    2012-01-01

    The purpose of this article is to present the main aspects regarding project planning. This study is generally based on the fourth edition of the Guide to the Project Management Body of Knowledge (PMBOK Guide) developed by the Project Management Institute (PMI) in 2008. According to this edition of PMBOK, project planning involves a group of processes required to establish the scope of the project, refine the objectives, and define the actions that must be undertaken to attain the objectives ...

  7. IT Project Management Metrics

    OpenAIRE

    Paul POCATILU

    2007-01-01

    Many software and IT projects fail in completing theirs objectives because different causes of which the management of the projects has a high weight. In order to have successfully projects, lessons learned have to be used, historical data to be collected and metrics and indicators have to be computed and used to compare them with past projects and avoid failure to happen. This paper presents some metrics that can be used for the IT project management.

  8. Project Phase Dependent Configuration of Project Management Information Systems

    OpenAIRE

    Bērziša, S; Grabis, J.

    2012-01-01

    Project management information systems ensure the collection and display of project information. The project information changes depend upon the project environment. According to project environment and requirements, the configuration of project management information system is ensured by means of an approach to configuration of project management information systems. However, topicality of information and access to it change during the project life cycle depending upo...

  9. A PROJECT WITHIN MICROSOFT PROJECT 2007

    Directory of Open Access Journals (Sweden)

    Emil COSMA

    2009-10-01

    Full Text Available The main purpose of this article is to emphasize the innumerable advantages of the Microsoft Project 2007 projecting environment that a project manager could benefit of. More exactly, Project Management stands for a function that is recognized within the majority of domains. A project is defined as “a temporary effort made for creating a product or a unique service”. A projects’ administrative programme within an informational system (such as Microsoft Project, Primavera Planner represents a “database that is in concordance with time”. It should help proceeding the required operations and, at the same time, to look and behave the same way other frequently utilized productive programmes. It keeps accounts of all information regarding the job requests, period and the project’s needed resources and visualizes the project’s plan in standard, well-defined formats, organizes the activities and resources consistently and efficiently,shares information regarding the project with all persons involved in an intranet or Internet network, and communicates efficiently with the resources and other involved persons, permitting at the same time the project manager to take the final control/decision as his/her responsibility.

  10. The Portable Tube Washer Project : project report

    OpenAIRE

    Døviken, Bjørnar D.; Lind, Henrik; Parken, Olav; Araya, Alexander

    2015-01-01

    The project group was assigned to develop and construct a fully automated, portable tube washer for the internal washing of small-bore hydraulic pipes; as well as plan, manage and document the project itself. Unfortunately, the physical construction of the product could not be realized due to insufficient budget funds that could not be raised.

  11. Information systems project management

    CERN Document Server

    Olson, David

    2014-01-01

    Information Systems Project Management addresses project management in the context of information systems. It deals with general project management principles, with focus on the special characteristics of information systems. It is based on an earlier text, but shortened to focus on essential project management elements.This updated version presents various statistics indicating endemic problems in completing information system projects on time, within budget, at designed functionality. While successful completion of an information systems project is a challenge, there are some things that ca

  12. Overview about project planning

    Directory of Open Access Journals (Sweden)

    Catalin Drob

    2012-12-01

    Full Text Available The purpose of this article is to present the main aspects regarding project planning. This study is generally based on the fourth edition of the Guide to the Project Management Body of Knowledge (PMBOK Guide developed by the Project Management Institute (PMI in 2008. According to this edition of PMBOK, project planning involves a group of processes required to establish the scope of the project, refine the objectives, and define the actions that must be undertaken to attain the objectives of the project.

  13. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  14. Project report - an overview of the project and experiences with project management

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Mikkelsen, Bent Egberg

    1996-01-01

    A collection of the project planning and the experiences with project management from the Catering 2000 project.As appendieces articles etc. from journals, newspapers etc. about the project.......A collection of the project planning and the experiences with project management from the Catering 2000 project.As appendieces articles etc. from journals, newspapers etc. about the project....

  15. Pro web project management

    CERN Document Server

    Emond, Justin

    2012-01-01

    Caters to an under-served niche market of small and medium-sized web consulting projects Eases people's project management pain Uses a clear, simple, and accessible style that eschews theory and hates walls of text

  16. The Phebus FP project

    International Nuclear Information System (INIS)

    This report summarizes the pre-project studies concerning the PHEBUS FP facility. After recalling the programme objectives, it describes the projected modifications to the PHEBUS reactor, outlines new installations and justifies the selected options

  17. Successful project management

    CERN Document Server

    Young, Trevor L

    2016-01-01

    Successful Project Management, 5th edition, is an essential guide for anyone who wants to improve the success rate of their projects. It will help managers to maintain a balance between the demands of the customer, the project, the team and the organization. Covering the more technical aspects of a project from start to completion it contains practised and tested techniques, covering project conception and start-up, how to manage stake holders, effective risk management, project planning and launch and execution. Also including a brand new glossary of key terms, it provides help with evaluating your project as well as practical checklists and templates to ensure success for any ambitious project manager. With over one million copies sold, the hugely popular Creating Success series covers a wide variety of topic, with the latest editions including new chapters such as Tough Conversations and Treating People Right. This indispensable business skills collection is suited to a variety of roles, from someone look...

  18. Architectural project and research

    DEFF Research Database (Denmark)

    Lotz, Katrine

    2005-01-01

    Discussion of criterias for research including the researchers or designers own project as theme.......Discussion of criterias for research including the researchers or designers own project as theme....

  19. Earned value project management

    CERN Document Server

    Fleming, Quentin W

    2010-01-01

    Organizations that follow the principles of good Earned Value Management (EVM) create an environment that allows teams to successfully operate and thrive ? even in the face of challenges that could negatively impact their projects. Earned Value Project Management (EVPM) is a methodology used to measure and communicate the real physical progress of a project taking into account the work completed, the time taken and the costs incurred to complete that work. As a result, EVPM allows more educated and effective management decision-making, which helps evaluate and control project risk by measuring project progress in monetary terms. In the first two editions of Earned Value Project Management, Quentin W. Fleming and Joel M. Koppelman provided guidance for project management practitioners already familiar with EVPM, was well as those who were new to the use of this technique. The third edition expanded the information available on of EVPM for medium and smaller projects while still being relevant for larger projec...

  20. BioProject

    Data.gov (United States)

    U.S. Department of Health & Human Services — The BioProject database provides an organizational framework to access information about research projects with links to data that have been or will be deposited...

  1. MANAGING MULTICULTURAL PROJECT TEAMS

    Directory of Open Access Journals (Sweden)

    Cezar SCARLAT

    2014-06-01

    Full Text Available The article is based on literature review and authors’ own recent experience in managing multicultural project teams, in international environment. This comparative study considers two groups of projects: technical assistance (TA projects versus information technology (IT projects. The aim is to explore the size and structure of the project teams – according to the team formation and its lifecycle, and to identify some distinctive attributes of the project teams – both similarities and differences between the above mentioned types of projects. Distinct focus of the research is on the multiculturalism of the project teams: how the cultural background of the team members influences the team performance and team management. Besides the results of the study are the managerial implications: how the team managers could soften the cultural clash, and avoid inter-cultural misunderstandings and even conflicts – in order to get a better performance. Some practical examples are provided as well.

  2. Project Portfolio Management Software

    OpenAIRE

    Paul POCATILU

    2006-01-01

    In order to design a methodology for the development of project portfolio management (PPM) applications, the existing applications have to be studied. This paper describes the main characteristics of the leading project portfolio management software applications.

  3. Venezuela's Bolivarian Schools Project.

    Science.gov (United States)

    Diaz, Maria Magnolia Santamaria

    2002-01-01

    Discusses efforts by the Venezuelan government to improve the nation's school infrastructure through the Bolivarian Schools Project administered by the Ministry of Education, Culture and Sport. The project set educational principles which are guiding current school building efforts. (EV)

  4. RadWorks Project

    Data.gov (United States)

    National Aeronautics and Space Administration — For the first two years of the project (FY12-13), the RadWorks project has consisted of two top-level elements. The first element involved the prototype and...

  5. Capital Projects Application (CPA)

    Data.gov (United States)

    General Services Administration — Capital Projects application (CPA) provides users with the ability to maintain project related financial data for Budget Activity (BA) 51, 55, 64, 01, 02, 03, 04....

  6. Collaborative Contracting in Projects

    NARCIS (Netherlands)

    Suprapto, M.

    2016-01-01

    Project practitioners have increasingly recognized the importance of collaborative relationships to ensure successful executions of projects. However, the ability to sustain and consistenly drive real collaborative attitudes and behavior for achieving the desired outcomes remains of enduring practic

  7. The Alzheimer's Project

    Science.gov (United States)

    ... Navigation Bar Home Current Issue Past Issues The Alzheimer's Project Past Issues / Spring 2009 Table of Contents ... of this page please turn Javascript on. The Alzheimer's Project A 4-Part Documentary Series Starting May ...

  8. Project Tasks in Robotics

    DEFF Research Database (Denmark)

    Sørensen, Torben; Hansen, Poul Erik

    1998-01-01

    Description of the compulsary project tasks to be carried out as a part of DTU course 72238 Robotics......Description of the compulsary project tasks to be carried out as a part of DTU course 72238 Robotics...

  9. Integrated project support environments the ASPECT project

    CERN Document Server

    Brown, Alan W

    1991-01-01

    A major part of software engineering developments involve the use of computing tools which facilitate the management, maintenance, security, and building of long-scale software engineer projects. Consequently, there have been a proliferation of CASE tools and IPSES. This book looks at IPSES in general and the ASPECT project in particular, providing design and implementation details, as well as locating ASPECT in IPSE developments.Survey of integrated project support environments for more efficient software engineering**Description of a large scale IPSE--ASPECT**Evaluation of formal methods in

  10. Project mechanisms challenges

    International Nuclear Information System (INIS)

    The project mechanism complete the quotas systems concerning the carbon dioxide emissions market. The author explains and discusses these mechanisms and provides a panorama of the existing and developing projects. More specially she brings information on the mechanism of clean developments and renewable energies, the coordinated mechanisms, the agricultural projects, the financing of the projects and the exchange systeme of the New south Wales. (A.L.B.)

  11. The PEC headworks project

    International Nuclear Information System (INIS)

    The PEC Headworks Project is a single-unit hydroelectric facility located at the headworks of the Potholes East Canal at O'Sullivan Dam on the Potholes reservoir near Moses Lake, Washington. The project was developed through exceptional coordination and cooperation between the local utility district, irrigation districts, and federal and state agencies. The plant was put into commercial operation in 1990. This paper describes the cooperative effort which developed the project and the distinctive technical features of the project

  12. Agile & Distributed Project Management

    DEFF Research Database (Denmark)

    Pries-Heje, Jan; Pries-Heje, Lene

    2011-01-01

    Scrum has gained surprising momentum as an agile IS project management approach. An obvious question is why Scrum is so useful? To answer that question we carried out a longitudinal study of a distributed project using Scrum. We analyzed the data using coding and categorisation and three carefully...... and coordination mechanisms by allowing both local and global articulation of work in the project. That is why Scrum is especially useful for distributed IS project management and teamwork....

  13. Map Projection Transitions

    OpenAIRE

    Nedjeljko Frančula; Miljenko Lapaine

    2013-01-01

    Map Projection Transitions is a very successful web application about map projections. The web page (http://www.jasondavies.com/maps/transition) pre­sents a world map with graticule and country borders in the oblique Aitoff projection, with the South Pole. The map is not static, but animated. The South Pole moves toward the bottom and Earth rotates around its poles. The animation lasts five seconds, after which the projection changes and movement continues for five seconds, after which the pr...

  14. Methodologies of project management

    OpenAIRE

    Wojciech Macek

    2010-01-01

    This paper presents comparison of three most popular project management standards belonging to a wider group of models (for example, PMBOK, Prince 2, CMMI, ISO 10006, BS 6079, IPMA Competence Baseline, European Commission Project Cycle Management Guidelines). The author discusses methods of project management according to PMBoK, Prince 2 and ISO 10006, some chosen criteria and fields of knowledge, such as general regulations of standards, project range management, resources management, and pr...

  15. Transformational Leadershipin Software Projects

    OpenAIRE

    MOUSAVIKHAH, MARYAM

    2013-01-01

    Lack of management in software projects is among the most important reasons for the failure of this kind of projects. Considering this fact, in addition to high rate of IS (Information System) projects’ failure, and the lack of leadership studies in IS field, it is necessary to pay more attention to the concept of leadership in software projects. Transformational leadership as one of the most popular leadership theories, although might bring specific advantages for this kind of projects, has ...

  16. The USE Project

    DEFF Research Database (Denmark)

    Frøkjær, E.; Hornbæk, K.; Høegh, Rune Thaarup;

    2006-01-01

    This paper provides experience from activities in the USE project. The USE project is a research project that aims at bridging the gap between usability evaluation and user interface design. It is conducted from 2005 to 2008 in collaboration between researchers from Aalborg University...

  17. The Eggen Card Project

    Science.gov (United States)

    Silvis, G.

    2014-06-01

    (Abstract only) Olin Eggen, noted astronomer (1919-1998), left to us all his raw observation records recorded on 3x5 cards. This project is to make all this data available as an online resource. History and progress of the project will be presented. Project details available at: https://sites.google.com/site/eggencards/home.

  18. Humane Education Projects Handbook.

    Science.gov (United States)

    Junior League of Ogden, UT.

    This handbook was developed to promote interest in humane education and to encourage the adoption of humane education projects. Although specifically designed to assist Junior Leagues in developing such projects, the content should prove valuable to animal welfare organizations, zoos, aquariums, nature centers, and other project-oriented groups…

  19. Building Project Competence

    DEFF Research Database (Denmark)

    Pemsel, Sofia; Wiewiora, Anna

    This research investigates the development of project competence, and particularly, three related dynamic capabilities (shifting, adapting, leveraging) that contribute to project competence development. In doing so, we make use of the emerging literature on knowledge governance and theorize how...... of dynamic capability building promoting project competence development....

  20. Projection: A Bibliography.

    Science.gov (United States)

    Pedrini, D. T.; Pedrini, Bonnie C.

    Sigmund Freud and his associates did much clinical work with the dynamic of projection, especially with regard to paranoid symptoms and syndromes. Much experimental work has also been done with projection. Sears evaluated the results of some of those studies. Murstein and Pryer sub-classified projection and reviewed typical studies. The…

  1. The Proposal Project

    Science.gov (United States)

    Pierce, Elizabeth

    2007-01-01

    The proposal project stretches over a significant portion of the semester-long sophomore course Professional Communication (ENG 250) at Monroe Community College. While developing their proposal project, students need to use time management skills to successfully complete a quality project on time. In addition, excellent oral and written…

  2. Nuclear safety projects 1995

    International Nuclear Information System (INIS)

    Action plans for the prevention of contamination in the Arctic regions is concretized in a number of international projects. The Norwegian Radiation Protection Authority is responsible for the follow-up of 13 projects. The report describes the development of these projects in 1995

  3. Projects as value constellations

    DEFF Research Database (Denmark)

    Laursen, Markus

    Creating value has been outlined as very central to projects applying the organizational perspective to projects. It has been suggested that value is created in value constellations or project networks, where actors work together to create value. However, research on the value creation process in...

  4. IX Disposition Project - project management plan

    International Nuclear Information System (INIS)

    This report presents plans for resolving saving and disposal concerns for ion exchange modules, cartridge filters and columns. This plan also documents the project baselines for schedules, cost, and technical information

  5. Underestimation of Project Costs

    Science.gov (United States)

    Jones, Harry W.

    2015-01-01

    Large projects almost always exceed their budgets. Estimating cost is difficult and estimated costs are usually too low. Three different reasons are suggested: bad luck, overoptimism, and deliberate underestimation. Project management can usually point to project difficulty and complexity, technical uncertainty, stakeholder conflicts, scope changes, unforeseen events, and other not really unpredictable bad luck. Project planning is usually over-optimistic, so the likelihood and impact of bad luck is systematically underestimated. Project plans reflect optimism and hope for success in a supposedly unique new effort rather than rational expectations based on historical data. Past project problems are claimed to be irrelevant because "This time it's different." Some bad luck is inevitable and reasonable optimism is understandable, but deliberate deception must be condemned. In a competitive environment, project planners and advocates often deliberately underestimate costs to help gain project approval and funding. Project benefits, cost savings, and probability of success are exaggerated and key risks ignored. Project advocates have incentives to distort information and conceal difficulties from project approvers. One naively suggested cure is more openness, honesty, and group adherence to shared overall goals. A more realistic alternative is threatening overrun projects with cancellation. Neither approach seems to solve the problem. A better method to avoid the delusions of over-optimism and the deceptions of biased advocacy is to base the project cost estimate on the actual costs of a large group of similar projects. Over optimism and deception can continue beyond the planning phase and into project execution. Hard milestones based on verified tests and demonstrations can provide a reality check.

  6. Disaster Video Gallery Project

    OpenAIRE

    Fesseha, ZeleAlem

    2012-01-01

    Project Report.docx Project Report.pdf Project Presentation.pptx Project Presentation.pdf Sample_YouTube_Videos_Raw.txt Sample_YouTube_Videos_Readable.txt The goal of this project was to collect YouTube videos for carefully selected events. The videos were manually collected and verified to be relevant to the specific events. The collection together with short description included with each video can later be used to automate the process of collecting videos pertaining to pa...

  7. Fundamentals of Project Management

    CERN Document Server

    Heagney, Joseph

    2011-01-01

    With sales of more than 160,000 copies, Fundamentals of Project Management has helped generations of project managers navigate the ins and outs of every aspect of this complex discipline. Using a simple step-by-step approach, the book is the perfect introduction to project management tools, techniques, and concepts. Readers will learn how to: ò Develop a mission statement, vision, goals, and objectives ò Plan the project ò Create the work breakdown structure ò Produce a workable schedule ò Understand earned value analysis ò Manage a project team ò Control and evaluate progress at every stage.

  8. Construction Project Organization

    OpenAIRE

    Pytlíčková, Kateřina

    2014-01-01

    The bachelor‘s thesis deals with „Construction Project Organization“. The theoretical part of this thesis explains the basic concepts of project management, describes the project´s life cycle, time planning and deals with the change management at the end of the theoretical part. The practical part deals with the project management of construction and mainly with time planning done by construction work schedule. The issue is solved on a real project led by the Czech construction company, and t...

  9. Project Decision Chain

    DEFF Research Database (Denmark)

    Rolstadås, Asbjørn; Pinto, Jeffrey K.; Falster, Peter;

    2015-01-01

    To add value to project performance and help obtain project success, a new framework for decision making in projects is defined. It introduces the project decision chain inspired by the supply chain thinking in the manufacturing sector and uses three types of decisions: authorization, selection......, and plan decision. A primitive decision element is defined where all the three decision types can be accommodated. Each task in the primitive element can in itself contain subtasks that in turn will comprise new primitive elements. The primitive elements are nested together in a project decision chain....

  10. LDRD final report on "Pumping up CO2 and conversion into useful molecules" (LDRD 105932).

    Energy Technology Data Exchange (ETDEWEB)

    Kemp, Richard Alan; Stewart, Constantine A.; Dickie, Diane A. (University of New Mexico, Albuquerque, NM)

    2009-11-01

    Group 12 metal cyclam complexes and their derivatives as well as (octyl){sub 2}Sn(OMe){sub 2} were examined as potential catalysts for the production of dimethyl carbonate (DMC) using CO{sub 2} and methanol. The zinc cyclams will readily take up carbon dioxide and methanol at room temperature and atmospheric pressure to give the metal methyl carbonate. The tin exhibited an improvement in DMC yields. Studies involving the reaction of bis-phosphino- and (phosphino)(silyl)-amido group 2 and 12 complexes with CO{sub 2} and CS{sub 2} were performed. Notable results include formation of phosphino-substituted isocyanates, fixation of three moles of CO{sub 2} in an unprecedented [N(CO{sub 2}){sub 3}]{sup 3-} anion, and rapid splitting of CS{sub 2} by main group elements under extremely mild conditions. Similar investigations of divalent group 14 silyl amides led to room temperature splitting of CO{sub 2} into CO and metal oxide clusters, and the formation of isocyanates and carbodiimides.

  11. Map Projection Transitions

    Directory of Open Access Journals (Sweden)

    Nedjeljko Frančula

    2013-06-01

    Full Text Available Map Projection Transitions is a very successful web application about map projections. The web page (http://www.jasondavies.com/maps/transition pre­sents a world map with graticule and country borders in the oblique Aitoff projection, with the South Pole. The map is not static, but animated. The South Pole moves toward the bottom and Earth rotates around its poles. The animation lasts five seconds, after which the projection changes and movement continues for five seconds, after which the projection changes again. Names of projections appear in a separate window. There are a total of 56 projections. The South Pole eventually becomes invisible and the North Pole appears at the top. Various parts of Earth appear in the center of the map by rotating around the poles.

  12. Environmental Science: 49 Science Fair Projects. Science Fair Projects Series.

    Science.gov (United States)

    Bonnet, Robert L.; Keen, G. Daniel

    This book contains 49 science fair projects designed for 6th to 9th grade students. Projects are organized by the topics of soil, ecology (projects in habitat and life cycles), pests and controls (projects in weeds and insects), recycling (projects in resources and conservation), waste products (projects in decomposition), microscopic organisms,…

  13. Laboratory directed research and development annual report. Fiscal year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-01

    The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. This report represents Pacific Northwest Laboratory`s (PNL`s) LDRD report for FY 1994. During FY 1994, 161 LDRD projects were selected for support through PNL`s LDRD project selection process. Total funding allocated to these projects was $13.7 million. Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our {open_quotes}core competencies.{close_quotes} Currently, PNL`s core competencies have been identified as integrated environmental research; process science and engineering; energy systems development. In this report, the individual summaries of LDRD projects (presented in Section 1.0) are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. Projects within the three core competency areas were approximately 91.4 % of total LDRD project funding at PNL in FY 1994. A significant proportion of PNL`s LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. Funding allocated to each of these projects is typically $35K or less. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL`s LDRD program, the management process used for the program, and project summaries for each LDRD project.

  14. Relationships and project marketing success

    DEFF Research Database (Denmark)

    Skaates, Maria Anne; Tikkanen, Henrikki; Lindblom, Jarno

    2002-01-01

    Project operations are a dominating mode of international business. Managing relationships and networks is crucial to project marketing success both at the level of the individual project and at the level of multiple projects. This article first defines key characteristics of project business, id...... projects, as well as on relevant environmental factors in the project marketing milieu, instead of using resources on sporadic or last minute running after potential projects.......Project operations are a dominating mode of international business. Managing relationships and networks is crucial to project marketing success both at the level of the individual project and at the level of multiple projects. This article first defines key characteristics of project business......, identifies potentially relevant actors in the project marketing milieu, and emphasizes the importance of constantly nurturing project business relationships, also in "sleeping relationship" periods where concrete projects are not expected. Thereafter the points made are illustrated with a Finnish...

  15. The CHPRC Columbia River Protection Project Quality Assurance Project Plan

    Energy Technology Data Exchange (ETDEWEB)

    Fix, N. J.

    2008-11-30

    Pacific Northwest National Laboratory researchers are working on the CHPRC Columbia River Protection Project (hereafter referred to as the Columbia River Project). This is a follow-on project, funded by CH2M Hill Plateau Remediation Company, LLC (CHPRC), to the Fluor Hanford, Inc. Columbia River Protection Project. The work scope consists of a number of CHPRC funded, related projects that are managed under a master project (project number 55109). All contract releases associated with the Fluor Hanford Columbia River Project (Fluor Hanford, Inc. Contract 27647) and the CHPRC Columbia River Project (Contract 36402) will be collected under this master project. Each project within the master project is authorized by a CHPRC contract release that contains the project-specific statement of work. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by the Columbia River Project staff.

  16. River Protection Project (RPP) Project Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    SEEMAN, S.E.

    2000-04-01

    The U.S. Department of Energy (DOE), in accordance with the Strom Thurmond National Defense Authorization Act for Fiscal Year 1999, established the Office of River Protection (ORP) to successfully execute and manage the River Protection Project (RPP), formerly known as the Tank Waste Remediation System (TWRS). The mission of the RPP is to store, retrieve, treat, and dispose of the highly radioactive Hanford tank waste in an environmentally sound, safe, and cost-effective manner. The team shown in Figure 1-1 is accomplishing the project. The ORP is providing the management and integration of the project; the Tank Farm Contractor (TFC) is responsible for providing tank waste storage, retrieval, and disposal; and the Privatization Contractor (PC) is responsible for providing tank waste treatment.

  17. Risk Management in Construction Projects

    OpenAIRE

    Jakše, Tadej

    2006-01-01

    Risk management in construction projects Each project is unique and therefore risk is associated with any project. Time limitation, dynamic and unstable character of construction project result in situations where new risks and uncertainties frequently appear. As a consequence, budget and deadlines specified by the construction project plan are often exceeded. Risk management in construction projects is required if adverse effects of project risks upon the project goals (time, ...

  18. Project GlobWave

    Science.gov (United States)

    Busswell, Geoff; Ash, Ellis; Piolle, Jean-Francois; Poulter, David J. S.; Snaith, Helen; Collard, Fabrice; Sheera, Harjit; Pinnock, Simon

    2010-12-01

    The ESA GlobWave project is a three year initiative, funded by ESA and CNES, to service the needs of satellite wave product users across the globe. Led by Logica UK, with support from CLS, IFREMER, SatOC and NOCS, the project will provide free access to satellite wave data and products in a common format, both historical and in near real time, from various European and American SAR and altimeter missions. Building on the successes of similar projects for Sea Surface Temperature and ocean colour, the project aims to stimulate increased use and analysis of satellite wave products. In addition to common-format satellite data the project will provide comparisons with in situ measurements, interactive data analysis tools and a pilot spatial wave forecast verification scheme for operational forecast production centres. The project will begin operations in January 2010, with direction from regular structured user consultation.

  19. Battleground Energy Recovery Project

    Energy Technology Data Exchange (ETDEWEB)

    Bullock, Daniel [USDOE Gulf Coast Clean Energy Application Center, Woodlands, TX (United States)

    2011-12-31

    In October 2009, the project partners began a 36-month effort to develop an innovative, commercial-scale demonstration project incorporating state-of-the-art waste heat recovery technology at Clean Harbors, Inc., a large hazardous waste incinerator site located in Deer Park, Texas. With financial support provided by the U.S. Department of Energy, the Battleground Energy Recovery Project was launched to advance waste heat recovery solutions into the hazardous waste incineration market, an area that has seen little adoption of heat recovery in the United States. The goal of the project was to accelerate the use of energy-efficient, waste heat recovery technology as an alternative means to produce steam for industrial processes. The project had three main engineering and business objectives: Prove Feasibility of Waste Heat Recovery Technology at a Hazardous Waste Incinerator Complex; Provide Low-cost Steam to a Major Polypropylene Plant Using Waste Heat; and Create a Showcase Waste Heat Recovery Demonstration Project.

  20. Honesty in projects

    OpenAIRE

    Kvalnes, Øyvind

    2014-01-01

    Purpose – The purpose of this paper is to explore how the concept of honesty can shed light on misreporting issues in projects. Research on honesty can be useful for practitioners and researchers in project management, in order to understand and counter the withholding and distortion of relevant information from projects. In moral psychology, dishonesty is often explained as a result of moral neutralization. The paper provides an account of how neutralization can lead to dishonest...

  1. Operational waste volume projection

    Energy Technology Data Exchange (ETDEWEB)

    Koreski, G.M.

    1996-09-20

    Waste receipts to the double-shell tank system are analyzed and wastes through the year 2015 are projected based on generation trends of the past 12 months. A computer simulation of site operations is performed, which results in projections of tank fill schedules, tank transfers, evaporator operations, tank retrieval, and aging waste tank usage. This projection incorporates current budget planning and the clean-up schedule of the Tri-Party Agreement. Assumptions were current as of June 1996.

  2. Scrum project management tool

    OpenAIRE

    Smolnik, Uroš

    2011-01-01

    For this thesis I made an application that will help manage projects using Scrum methodology. The objective was to make an application that students will use to work on their projects when using Scrum methodology. The application should enable managing project data by displaying measurement results in tabular form and also in the form of various diagrams. The theoretical part of the thesis is focused on presenting Scrum methodology by describing the introduction of measurements in methodol...

  3. Quality incidents in projects

    OpenAIRE

    Eren, Serkan

    2010-01-01

    A quality incident is an occurrence that has a negative consequence on time, cost and quality.These incidents are important for quality management in the projects. Similar to Health,Safety and Environment Incidents (HSE incidents) which are widely used in organizations allaround the world and in their projects, quality incidents should also be reported. For thepurpose of this, quality incident reporting systems can be used.The main purpose of this project is to define and explain the current ...

  4. Spin projection chromatography

    OpenAIRE

    Danieli, Ernesto P.; Pastawski, Horacio M.; Levstein, Patricia R.

    2003-01-01

    We formulate the many-body spin dynamics at high temperature within the non-equilibrium Keldysh formalism. For the simplest XY interaction, analytical expressions in terms of the one particle solutions are obtained for linear and ring configurations. For small rings of even spin number, the group velocities of excitations depend on the parity of the total spin projection. This should enable a dynamical filtering of spin projections with a given parity i.e. a Spin projection chromatography.

  5. Computer Assets Recovery Project

    Science.gov (United States)

    CortesPena, Aida Yoguely

    2010-01-01

    This document reports on the project that was performed during the internship of the author. The project involved locating and recovering machines in various locations that Boeing has no need for, and therefore requires that they be transferred to another user or transferred to a non-profit organization. Other projects that the author performed was an inventory of toner and printers, loading new computers and connecting them to the network.

  6. Organization of project management

    International Nuclear Information System (INIS)

    When speaking about interfaces within a project and their management, one has to understand and define what an interface is. In general, each component facing another one and each person working on a project with another person represents an interface. Therefore a project will consist practically in its entirety of interfaces with components and people sandwiched between them. This paper is limited to the most important interfaces with a focus on the problems occuring at them and their resolution. (orig.)

  7. Project Risk Management Phases

    OpenAIRE

    Claudiu-George BOCEAN

    2008-01-01

    Risk management is the human activity which integrates recognition of risk, risk assessment, developing strategies to manage it, and mitigation of risk using managerial resources. Notwithstanding the domain of activities where they are conducted, projects often entail risks, and risk management has been widely recognized as a success factor in project management. Following a concept clarification on project risk management, this paper presents a generic list steps in the risk management proce...

  8. Projections of fractal percolations

    OpenAIRE

    Rams, Michal; Simon, Károly

    2013-01-01

    In this paper we study the radial and orthogonal projections and the distance sets of the random Cantor sets $E\\subset \\mathbb{R}^2 $ which are called Mandelbrot percolation or percolation fractals. We prove that the following assertion holds almost surely: if the Hausdorff dimension of $E$ is greater than 1 then the orthogonal projection to \\textbf{every} line, the radial projection with \\textbf{every} center, and distance set from \\textbf{every} point contain intervals.

  9. The mindful project manager

    OpenAIRE

    Gunnar Pétur Hauksson 1985

    2015-01-01

    The goal of this thesis is to bridge the gap between the topics of: a) Leadership competences as a success factor in project management, b) The benefits of mindfulness meditation in the context of management and leadership. A literature review of both topics is presented. The convergence point of these two topics is then analyzed in order to shed light on if and how mindfulness meditation practice of project managers could potentially enhance key leadership competences for project managers an...

  10. Project Identification and Formulation

    DEFF Research Database (Denmark)

    Lund, Søren; Lønholdt, Jens

    2005-01-01

    Provides the necessary conceptual framework and tools to assess all appropriate aspects of water and sanitation projects in developing countries. Appeals to graduate environmental engineering students, practitioners, economists, sociologists, and institutional planners working with water and sani......Provides the necessary conceptual framework and tools to assess all appropriate aspects of water and sanitation projects in developing countries. Appeals to graduate environmental engineering students, practitioners, economists, sociologists, and institutional planners working with water...... and sanitation projects in developing countries....

  11. Spin projection chromatography

    Science.gov (United States)

    Danieli, E. P.; Pastawski, H. M.; Levstein, P. R.

    2004-01-01

    We formulate the many-body spin dynamics at high temperature within the non-equilibrium Keldysh formalism. For the simplest XY interaction, analytical expressions in terms of the one particle solutions are obtained for linear and ring configurations. For small rings of even spin number, the group velocities of excitations depend on the parity of the total spin projection. This should enable a dynamical filtering of spin projections with a given parity i.e., a spin projection chromatography.

  12. Evaluating watershed management projects:

    OpenAIRE

    Kerr, John; Chung, Kimberly

    2001-01-01

    Watershed projects play an increasingly important role in managing soil and water resources throughout the world. Research is needed to ensure that new projects draw upon lessons from their predecessors' experiences. However, the technical and social complexities of watershed projects make evaluation difficult. Quantitative and qualitative evaluation methods, which traditionally have been used separately, both have strengths and weaknesses. Combining them can make evaluation more effective, p...

  13. Aerospace Systems Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Proposal Title: Aerospace Systems Monitor PHASE 1 Technical Abstract: This Phase II STTR project will continue development and commercialization of the Aerospace...

  14. Composites for Exploration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The project will devise test and development approaches to support development of large scale composite payload fairing structures, including conducting tests and...

  15. Hybrid Nanocomposite Photovoltaics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project will develop an innovative solar cell design that combines nanotechnology with conducting polymer...

  16. Mayan Forest Road Projects

    DEFF Research Database (Denmark)

    Conde, Dalia Amor

    2008-01-01

    rates of return on investment on the basis of project economics, whilst others would be negative if only the carbon dioxide emissions (225million tonnes over 30 years) were accounted for. A fuller evaluation including biodiversity values would have tilted the conclusions more firmly in the direction......Road-building projects in the Mayan Biosphere Reserve to connect Mexico and Guatemala were subjected to a cost-benefit evaluation. Up to an estimated 311,000 hectares of jaguar habitat were found to be at risk of deforestation due to these projects. Some of the projects were shown to have negative...

  17. Photovoltaic Wire Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project will investigate a new architecture for photovoltaic devices based on nanotechnology: photovoltaic wire. The...

  18. FLEXI Project Management Survey

    Science.gov (United States)

    Rohunen, Anna; Krzanik, Lech; Kuvaja, Pasi; Similä, Jouni; Rodriguez, Pilar; Hyysalo, Jarkko; Linna, Tommi

    FLEXI Project Management Survey (FLEXI PMS) has been established to gain detailed knowledge on how the software industry - in particular successful companies - manages agile software development. FLEXI PMS investigates the actual agile values, principles, practices and contexts. The survey is supported by a careful literature review and analysis of existing studies. Special attention is attached to large, multi-site, multi-company and distributed projects - the target area of FLEXI project. The survey is intended to provide solid data for further knowledge acquisition and project/company positioning with regard to feasible agile management practices.

  19. Scrum Project Management

    CERN Document Server

    Pries, Kim H

    2010-01-01

    Scrum, which was originally invented solely for software development, can now be applied to all types of projects. This book shows project managers how to implement Scrum by explaining the artifacts, rituals, and roles used. The text provides Scrum planning methods to control project scope and schedule as well as Scrum tracking methods to focus teams on improving throughput and streamlining communications. The authors show how to combine traditional project methods with Scrum and how to adapt the familiar work breakdown structure to create Scrum backlogs and sprints. They also demonstrate how

  20. HERMES project management I

    CERN Document Server

    CERN. Geneva

    2013-01-01

    A two-hours course on the HERMES Project Management Methodology to the attention of Project Leaders and Project Participants. The methodology is quickly presented; the focus is put on the roles and responsibilities and on the project initiation phase. The course is given in French with slides in English. On April 22nd 2013, a new version of the HERMES methodology was made public. For practical reasons, this course is still given based on the 2009 version of HERMES (a.k.a. HERMES 4).

  1. A DC Transformer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — During the period of this project three different possible DC transformer concepts were proposed, theoretically modeled, and then experimentally tested with the...

  2. Impact of Project Leadership Facets on Project Outcome

    Directory of Open Access Journals (Sweden)

    Arslan Ayub

    2015-08-01

    Full Text Available The study analyzes the role of project leadership facets on effective project outcome. Numerous such initiatives have already been taken on project outcome/performance in the context of apposite leadership styles or project management. However, the current study is unique in the milieu of project outcome that it introduces a new leadership approach, which throws light on the significance of variant leadership facets on project outcome. The study uses explanatory approach; primary data is collected from project management professionals working in different project organizations. The study uses structural equation model (SEM technique to test the hypothesis. The study found a positive relationship between project leadership facets and project outcome.

  3. Embedded Linux projects using Yocto project cookbook

    CERN Document Server

    González, Alex

    2015-01-01

    If you are an embedded developer learning about embedded Linux with some experience with the Yocto project, this book is the ideal way to become proficient and broaden your knowledge with examples that are immediately applicable to your embedded developments. Experienced embedded Yocto developers will find new insight into working methodologies and ARM specific development competence.

  4. River Protection Project (RPP) Project Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    NAVARRO, J.E.

    2001-03-07

    The Office of River Protection (ORP) Project Management Plan (PMP) for the River Protection Project (RPP) describes the process for developing and operating a Waste Treatment Complex (WTC) to clean up Hanford Site tank waste. The Plan describes the scope of the project, the institutional setting within which the project must be completed, and the management processes and structure planned for implementation. The Plan is written from the perspective of the ORP as the taxpayers' representative. The Hanford Site, in southeastern Washington State, has one of the largest concentrations of radioactive waste in the world, as a result of producing plutonium for national defense for more than 40 years. Approximately 53 million gallons of waste stored in 177 aging underground tanks represent major environmental, social, and political challenges for the U.S. Department of Energy (DOE). These challenges require numerous interfaces with state and federal environmental officials, Tribal Nations, stakeholders, Congress, and the US Department of Energy-Headquarters (DOE-HQ). The cleanup of the Site's tank waste is a national issue with the potential for environmental and economic impacts to the region and the nation.

  5. BODIES OF KNOWLEDGE IN PROJECT MANAGEMENT AND PROJECT QUALITY MANAGEMENT

    OpenAIRE

    Tamara Gvozdenovic; Mirjana Miljanovic; Aleksandar Jegdic; Zeljko Crnogorcic

    2008-01-01

    One of the main trends is standardization of project management. Some of the most important bodies of knowledge in project management, which were created by professional associations for project management are given in this paper. The main of the project management, apart from minimization of time, resources and costs, is to finish the project in the required quality, i.e. it is very important during the whole process of project management to provide realizing the project without any deviatio...

  6. The Petty Projection Inequality for Lp-Mixed Projection Bodies

    Institute of Scientific and Technical Information of China (English)

    Wei Dong WANG; Gang Song LENG

    2007-01-01

    Recently,Lutwak,Yang and Zhang posed the notion of Lp-projection body and established the Lp-analog of the Petty projection inequality.In this paper,the notion of Lp-mixed projection bodyis introduced--the Lp-projection body being a special case.The Petty projection inequality,as well asLutwak's quermassintegrals (Lp-mixed quermassintegrals) extension of the Petty projection inequality,is established for Lp-rnixed projection body.

  7. Classifying IS Project Problems

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas

    2006-01-01

    The literature contains many lists of IS project problems, often in the form of risk factors. The problems sometimes appear unordered and overlapping, which reduces their usefulness to practitioners as well as theoreticians. This paper proposes a list of criteria for formulating project problems...

  8. Sustainable Energy (SUSEN) project

    International Nuclear Information System (INIS)

    Research Centre Rez and University of West Bohemia started preparatory work on the 'Sustainable Energy' project, financed from EU structural funds. The goals and expected results of the project, its organization, estimated costs, time schedule and current status are described. (orig.)

  9. Massive wildlife project outlined

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — News article on the Chase Lake Prairie Project that is centered on the Chase Lake National Wildlife Refuge. Over the next 11 years the project aims to support 1.3...

  10. The Roskilde Project

    DEFF Research Database (Denmark)

    Bastrup-Birk, A.; Clark, D. R.

    This report is a result of one of the Danish support projects for the European Environmental Agency during the period 1995-1996.......This report is a result of one of the Danish support projects for the European Environmental Agency during the period 1995-1996....

  11. Distortion in Perspective Projection

    Science.gov (United States)

    Kelso, Robert P., Sr.

    2008-01-01

    The paper presents a unique approach in associating perspective projection with the image beheld by the eye and demonstrates that all graphical and photographic perspective projections must contain distortion when compared to the image beheld by the eye. (Contains 8 figures.)

  12. Assessment of Students Projects

    DEFF Research Database (Denmark)

    Kofoed, Lise B.; Stachowicz, Marian S.

    2012-01-01

    learning) pedagogical approaches. The experience of assessing first year projects from the Medialogy education at Aalborg University and third year projects from the Electrical and Computer Engineering Department at University of Minnesota, Duluth are presented, and the different methods discussed....... The conclusion is that process as well as product has to be assessed in a way which evaluates all aspects of students’ learning outcomes....

  13. iMarine project

    OpenAIRE

    Castelli, Donatella; Ellebroek, Anton; Taconet, Narc; Pagano, Pasquale (ISTI-CNR)

    2012-01-01

    The state-of-art of the iMarine project is presented. The project aim is establishing and operating an e‐infrastructure contributing to the implementation of the principles of the Ecosystem Approach to Fisheries Management and Conservation of Marine Living Resources

  14. Designing job enrichment projects.

    Science.gov (United States)

    Clakeley, G L

    1988-01-01

    This paper describes a management strategy for a job satisfaction program utilized in a large occupational therapy department. The goal of the program is to retain satisfied, productive employees and reduce attrition of therapists and assistants. The use of job enrichment projects for occupational therapy assistants will be presented with brief descriptions of two projects. PMID:23944880

  15. Meridian Project kicks off

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ As a major national project for S&T infrastructures, the Meridian Chain of Comprehensive Ground- Based Space Environment Monitors in the Eastern Hemisphere (dubbed as the Meridian Project) has been officially initiated. Its construction commencement ceremony was held on 5 January in Beijing.

  16. Spoofer Project: Spoofer Main

    OpenAIRE

    2014-01-01

    Center for Measurement and Analysis of Network Data (cMAND) Project. What: The Spoofer project measures the Internet's susceptibility to spoofed source address IP packets. Malicious users capitalize on the ability to "spoof" source IP addresses for anonymity, indirection, targeted attacks and security circumvention. Compromised hosts on networks that permit IP spoofing enable a wide variety of attacks.

  17. The Comic Book Project

    Science.gov (United States)

    Bitz, Michael

    2008-01-01

    The Comic Book Project (CBP) celebrates its eighth anniversary this year. The project, which just originated with one school in New York City, had grown to encompass thousands of students nationwide. The goal of the CBP is not to create comics the "Marvel way" or to develop the next Stan Lee. Rather, the goal is to give students the opportunity to…

  18. Avoiding Project Creep.

    Science.gov (United States)

    Kennerknecht, Norbert J.; Scarnati, James T.

    1998-01-01

    Discusses how to keep school district capital-improvement projects within budget. Examines areas where runaway costs creep into a project and ways of cutting or lessening these costs, such as using standard agreements, controlling architect's expense reimbursements, developing a quality-control process, and reducing document duplication. (GR)

  19. The Plate Tectonics Project

    Science.gov (United States)

    Hein, Annamae J.

    2011-01-01

    The Plate Tectonics Project is a multiday, inquiry-based unit that facilitates students as self-motivated learners. Reliable Web sites are offered to assist with lessons, and a summative rubric is used to facilitate the holistic nature of the project. After each topic (parts of the Earth, continental drift, etc.) is covered, the students will…

  20. Project Systematics of Annonaceae

    NARCIS (Netherlands)

    Maas, P.J.M.

    1983-01-01

    Recently a multidisciplinary investigation program on the systematics of Annonaceae was started at Utrecht with special emphasis on the Neotropics. This project will be carried out largely within the framework of the UNESCO-project Flora Neotronica. The first goal is to provide a modern classificati

  1. Project Quality Plan

    DEFF Research Database (Denmark)

    Sandborg-Petersen, Ulrik; Øhrstrøm, Peter

    This document defines the procedures, standards, and strategies which will be used to ensure high standards of quality of the work produced within the HANDS project. It contains the following sections......This document defines the procedures, standards, and strategies which will be used to ensure high standards of quality of the work produced within the HANDS project. It contains the following sections...

  2. Arizona's Florence Project.

    Science.gov (United States)

    Dallam, Elizabeth

    2001-01-01

    Describes the Florence Immigrant and Refugee Rights Project (Florence, Arizona) in which lawyers help individuals who are being detained in Florence. Explains that the project offers service to individuals at the detention center, helps children without guardians, and provides information to immigrant communities on their rights when arrested.…

  3. Visible Human Project

    Science.gov (United States)

    ... NLM Mobile Gallery Site Navigation Home The Visible Human Project ® Overview The Visible Human Project ® is an outgrowth of the NLM's 1986 ... dimensional representations of the normal male and female human bodies. Acquisition of transverse CT, MR and cryosection ...

  4. PPP projects in transport

    DEFF Research Database (Denmark)

    Petersen, Ole Helby; Carpintero, Samuel

    2014-01-01

    Public–private partnerships (PPPs) have been extensively used in Spain for the procurement of light rail systems. This paper analyses five projects that have been in operation for more than five years. The authors examine the reasoning behind the selection of the PPP projects, risk...

  5. Project Planning: An Analysis

    Directory of Open Access Journals (Sweden)

    Dr.S.S.Riaz Ahamed

    2010-01-01

    Full Text Available The purpose of the Planning stage is to analyze the project in terms of work breakdown, cost, resources, and timing. At the end of this stage all team members should be clear on the sub tasks and deliverables with the project, the time constraints they are working too and the roles and responsibilities that are expected from them.Software Project Plan defines what the work is, and how this work can be completed. This plan is developed at the beginning of the software project and is continually refined and improved as the work rocesses. It can be useful to management as a frame work for review and control the process of developing the software. Additionally, the Software Project Plan can define each of the major tasks and estimate the time and resources that are required to complete these tasks.

  6. Visualizations as Projection Devices

    DEFF Research Database (Denmark)

    Harty, Chris; Holm Jacobsen, Peter; Tryggestad, Kjell

    The aim of this paper is to inquire into the role of project visualizations in shaping healthcare spaces and practices. The study draws upon an ethnographic field study from a large on-going hospital construction project in Denmark, and focuses on the early phases of on-boarding the design team...... into the project organization. During the on-boarding visualizations multiplies in form, content and purpose, ranging from paper and digitally based projections of clinical work spaces and practices for the future hospital building in use, to paper and digitally based projections of the cost budget and time...... visualizations plays an active role in developing novel conceptions of space and how these are mobilized in the process of on-boarding, in terms of; design space, physical space, organizational space and economic space. Our findings show the visualizations of different spaces and how they are dynamically...

  7. Management of foreign projects

    International Nuclear Information System (INIS)

    Atomic Energy of Canada Ltd. has sold CANDU reactors to India, Pakistan, Argentina, Korea and Romania. Therefore, the management of foreign nuclear power projects is a vital issue to the Canadian nuclear industry. Offshore projects pose a variety of problems. The scope of the work may vary significantly, and the customers' imperatives and those of the governments involved may be in conflict. The language, culture and bureaucracy can be alien to Canadians. Communications, logistics and work methods can be unfamiliar and can vary from project to project. These challenges can be met with flexibility in roles and responsibilities, contractual arrangements, and project organizations. Well-trained, experienced, skilled personnel can be obtained by forming alliances with the private sector of the nuclear industry

  8. Solar renovation demonstration projects

    Energy Technology Data Exchange (ETDEWEB)

    Bruun Joergensen, O. [ed.

    1998-10-01

    In the framework of the IEA SHC Programme, a Task on building renovation was initiated, `Task 20, Solar Energy in Building Renovation`. In a part of the task, Subtask C `Design of Solar Renovation Projects`, different solar renovation demonstration projects were developed. The objective of Subtask C was to demonstrate the application of advanced solar renovation concepts on real buildings. This report documents 16 different solar renovation demonstration projects including the design processes of the projects. The projects include the renovation of houses, schools, laboratories, and factories. Several solar techniques were used: building integrated solar collectors, glazed balconies, ventilated solar walls, transparent insulation, second skin facades, daylight elements and photovoltaic systems. These techniques are used in several simple as well as more complex system designs. (au)

  9. Leading global projects for professional and accidental project leaders

    CERN Document Server

    Moran, Robert T

    2008-01-01

    This book is a must-read for anyone responsible for projects and initiatives that span functional and geographical divides. Authors Moran and Youngdahl bring extensive experience and learning from industry practice to present a clear and straightforward treatment of the leadership skills and knowledge required to lead projects that are global in nature. They have written the first book of its kind to address the three essential skills of global project leaders - strategic project management, project leadership, and cross-cultural leadership. The authors argue that global project leadership is an essential skill in our project-based world and that we are all either intentional or accidental project leaders. Intentional project leaders pursue formal project management education and even certification whereas accidental project leaders find themselves leading global projects and initiatives as a result of a special assignment or promotion. Moran and Youndahl have found that the vast majority of global projects ...

  10. A project model for the FreeBSD Project

    OpenAIRE

    2003-01-01

    This thesis provides a baseline on which a methodology for the FreeBSD Project can be built. The three results of this thesis are: - A descriptive "project model" for the FreeBSD Project - A set of "quality goals" for the project model - A "comparison" between the quality goals and the project model, giving us the quality of the project model The project model is based on project documents, interviews, mail archives and the experience of the author in working with the project. T...

  11. On grey relation projection model based on projection pursuit

    Institute of Scientific and Technical Information of China (English)

    Wang Shuo; Yang Shanlin; Ma Xijun

    2008-01-01

    Multidimensional grey relation projection value can be synthesized as one-dimensional projection value by u-sing projection pursuit model.The larger the projection value is,the better the model.Thus,according to the projection value,the best one can be chosen from the model aggregation.Because projection pursuit modeling based on accelera-ting genetic algorithm can simplify the implementation procedure of the projection pursuit technique and overcome its complex calculation as well as the difficulty in implementing its program,a new method can be obtained for choosing the best grey relation projection model based on the projection pursuit technique.

  12. The Ethiopian Flora Project: A springboard to other projects

    DEFF Research Database (Denmark)

    Demissew, Sebsebe; Brochmann, Christian; Kelbessa, Ensermu;

    2011-01-01

    The account reviews and analyses the scietific projects derived from activities in connection with the Ethiopian Flora Project, including the [Ethiopian] Monocot Project, the Afro-alpine "Sky-island" project, the Vegetation and Ecological Conditions of Plantations Project, the Fire Ecology Projec...

  13. Organization of BSc and MSc projects in project families

    DEFF Research Database (Denmark)

    Ottosen, Lisbeth M.; Goltermann, Per; Jensen, Pernille Erland

    2014-01-01

    This work reports organization of student thesis projects in project families, with the benefit to both teaching and learning. The project organization went from student projects broadly distributed on topics related to different research issues and individual supervision to project families with...

  14. projecting pARTicles, a STEAM project

    CERN Document Server

    Goldfarb, Steven; The ATLAS collaboration

    2016-01-01

    Agnes Chavez is a media artist based in the US (New Mexico) and involved in STEM Art Labs. An informal partnership initiated with some ATLAS physicists will develop further in 2016 through a series of workshops where Virtual Visits, Master Class material and the presence of a physicist will be gradually integrated. The project can be seen as an illustration of constructive and long term collaboration between artists, students and scientists.

  15. Basalt Waste Isolation Project Reclamation Support Project:

    Energy Technology Data Exchange (ETDEWEB)

    Brandt, C.A.; Rickard, W.H. Jr.; Cadoret, N.A.

    1992-06-01

    The Basalt Waste Isolation Project (BWIP) Reclamation Support Project began in the spring of 1988 by categorizing sites distributed during operations of the BWIP into those requiring revegetation and those to be abandoned or transferred to other programs. The Pacific Northwest Laboratory's role in this project was to develop plans for reestablishing native vegetation on the first category of sites, to monitor the implementation of these plans, to evaluate the effectiveness of these efforts, and to identify remediation methods where necessary. The Reclamation Support Project focused on three major areas: geologic hydrologic boreholes, the Exploratory Shaft Facility (ESF), and the Near-Surface Test Facility (NSTF). A number of BWIP reclamation sites seeded between 1989 and 1990 were found to be far below reclamation objectives. These sites were remediated in 1991 using various seedbed treatments designed to rectify problems with water-holding capacity, herbicide activity, surficial crust formation, and nutrient imbalances. Remediation was conducted during November and early December 1991. Sites were examined on a monthly basis thereafter to evaluate plant growth responses to these treatments. At all remediation sites early plant growth responses to these treatments. At all remediation sites, early plant growth far exceeded any previously obtained using other methods and seedbed treatments. Seeded plants did best where amendments consisted of soil-plus-compost or fertilizer-only. Vegetation growth on Gable Mountain was less than that found on other areas nearby, but this difference is attributed primarily to the site's altitude and north-facing orientation.

  16. Improving Project Manufacturing Coordination

    Directory of Open Access Journals (Sweden)

    Korpivaara Ville

    2014-09-01

    Full Text Available The objective of this research is to develop firms’ project manufacturing coordination. The development will be made by centralizing the manufacturing information flows in one system. To be able to centralize information, a deep user need assessment is required. After user needs have been identified, the existing system will be developed to match these needs. The theoretical background is achieved through exploring the literature of project manufacturing, development project success factors and different frameworks and tools for development project execution. The focus of this research is rather in customer need assessment than in system’s technical expertise. To ensure the deep understanding of customer needs this study is executed by action research method. As a result of this research the information system for project manufacturing coordination was developed to respond revealed needs of the stakeholders. The new system improves the quality of the manufacturing information, eliminates waste in manufacturing coordination processes and offers a better visibility to the project manufacturing. Hence it provides a solid base for the further development of project manufacturing.

  17. Vague project start makes project success of outsourced software development projects uncertain

    OpenAIRE

    Savolainen, Paula

    2010-01-01

    peer-reviewed A definition of a project success includes at least three criteria: 1) meeting planning goals, 2) customer benefits, and 3) supplier benefits. This study aims to point out the importance of the definition of the project start, the project start date, and what work should be included in the project effort in order to ensure the supplier's benefits. The ambiguity of the project start risks the profitability of the project and therefore makes project success at least from suppli...

  18. Projection Models 2010

    DEFF Research Database (Denmark)

    Illerup, J. B.; Birr-Pedersen, K.; Mikkelsen, M. H;

    to achieve the emission ceilings given in the Gothenburg Protocol and the EU directive on national emission ceilings in 2010. In addition to the basis scenario, 8 emission reduction scenarios for different sectors have been analysed in order to estimate the emission saving potential and financial and welfare-economic......Models for projection of SO2-, NOx-, NMVOC- and NH3-emissions to the atmosphere have been developed and the Danish emissions have been projected until 2010 from a basis scenario including all implemented and planned measures. The projections of the four pollutants indicate that it may be difficult...

  19. Arduino projects for dummies

    CERN Document Server

    Craft, Brock

    2013-01-01

    Discover all the amazing things you can do with Arduino Arduino is a programmable circuit board that is being used by everyone from scientists, programmers, and hardware hackers to artists, designers, hobbyists, and engineers in order to add interactivity to objects and projects and experiment with programming and electronics. This easy-to-understand book is an ideal place to start if you are interested in learning more about Arduino's vast capabilities. Featuring an array of cool projects, this Arduino beginner guide walks you through every step of each of the featured projects so

  20. One project`s waste is another project`s resource

    Energy Technology Data Exchange (ETDEWEB)

    Short, J.

    1997-02-01

    The author describes the efforts being made toward pollution prevention within the DOE complex, as a way to reduce overall project costs, in addition to decreasing the amount of waste to be handled. Pollution prevention is a concept which is trying to be ingrained into project planning. Part of the program involves the concept that ultimately the responsibility for waste comes back to the generator. Parts of the program involve efforts to reuse materials and equipment on new projects, to recycle wastes to generate offsetting revenue, and to increase awareness, accountability and incentives so as to stimulate action on this plan. Summaries of examples are presented in tables.

  1. CAREM Project Status

    Directory of Open Access Journals (Sweden)

    H. Boado Magan

    2011-01-01

    Full Text Available CAREM is a CNEA (Comisión Nacional de Energía Atómica project. This project consists of the development, design, and construction of a small nuclear power plant. First, a prototype of an electrical output of about 27 MW, CAREM 25, will be built in order to validate the innovation of the CAREM concept and then developed to commercial version. After several years of development, the CAREM Project reached such a maturity level that the Argentine government decided on the construction of CAREM prototype. Several activities are ongoing with the purpose of obtaining the construction permit for the CAREM prototype.

  2. Oluvil Port Development Project

    DEFF Research Database (Denmark)

    Frigaard, Peter; Margheritini, Lucia

    Oluvil Port Development Project is the first development of a large port infrastructure in the entire eastern coastline of Sri Lanka. The project is supported by the Danish Foreign Ministry. Feasibility studies and detailed design studies were carried out by Lanka Hydraulic Institute Ltd during...... has been observed. Severe erosion is seen north of the harbour and some accumulation of sand is seen south of the harbour. On a sandy coastline like the one in Oluvil such erosion problems as observed are very typical. The report: Oluvil Port Development Project: Studies on Beach Erosion written...

  3. Final Project Report

    DEFF Research Database (Denmark)

    Duer, Karsten

    1997-01-01

    as on the aerogel DGU that was developped during the project. B12 and B14 have measured the g-value and the U-value respectively of the aerogel DGU. Furthermore calculations of the energy saving potential by using aerogel windows in selected residential and commercial buildings under different climatic conditions...... were carried out as part of the A2/A3 project. The B1 Aerogel project has been carried out with partition of the following nations: Denmark, Finland, France,Germany, Japan, Norway, Sweden and the United Kingdom....

  4. The Methanol Economy Project

    Energy Technology Data Exchange (ETDEWEB)

    Olah, George [Univ. of Southern California, Los Angeles, CA (United States); Prakash, G. K. [Univ. of Southern California, Los Angeles, CA (United States)

    2014-02-01

    The Methanol Economy Project is based on the concept of replacing fossil fuels with methanol generated either from renewable resources or abundant natural (shale) gas. The full methanol cycle was investigated in this project, from production of methanol through bromination of methane, bireforming of methane to syngas, CO2 capture using supported amines, co-electrolysis of CO2 and water to formate and syngas, decomposition of formate to CO2 and H2, and use of formic acid in a direct formic acid fuel cell. Each of these projects achieved milestones and provided new insights into their respective fields.

  5. NAVAJO ELECTRIFICATION DEMONSTRATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Terry W. Battiest

    2008-06-11

    The Navajo Electrification Demonstration Project (NEDP) is a multi-year project which addresses the electricity needs of the unserved and underserved Navajo Nation, the largest American Indian tribe in the United States. The program serves to cumulatively provide off-grid electricty for families living away from the electricty infrastructure, line extensions for unserved families living nearby (less than 1/2 mile away from) the electricity, and, under the current project called NEDP-4, the construction of a substation to increase the capacity and improve the quality of service into the central core region of the Navajo Nation.

  6. Distributed Project Work

    DEFF Research Database (Denmark)

    Borch, Ole; Kirkegaard, B.; Knudsen, Morten;

    1998-01-01

    Project work has been used for many years at Aalborg University to improve learning of theory and methods given in courses. In a closed environment where the students are forming a group in a single room, the interaction behaviour is more or less given from the natural life. Group work in a distr...... to be very precises and with success used on the second test group. Distributed project work is coming pretty soon and with little improvement in server tools, projects in different topics with a large and inhomogeneous profile of users are realistic....

  7. WFIRST Project Science Activities

    Science.gov (United States)

    Gehrels, Neil

    2012-01-01

    The WFIRST Project is a joint effort between GSFC and JPL. The project scientists and engineers are working with the community Science Definition Team to define the requirements and initial design of the mission. The objective is to design an observatory that meets the WFIRST science goals of the Astr02010 Decadal Survey for minimum cost. This talk will be a report of recent project activities including requirements flowdown, detector array development, science simulations, mission costing and science outreach. Details of the interim mission design relevant to scientific capabilities will be presented.

  8. The Sizewell B project

    Energy Technology Data Exchange (ETDEWEB)

    Collier, John G. [Nuclear Electric plc, Barnwood (United Kingdom)

    2015-12-15

    The Sizewell B project has demonstrated the capability of the UK's manufacturing industry to undertake large projects and to meet the most demanding international standards - it is a triumph for the UK nuclear industry. The paper outlines the background to the decision to build Sizewell B, it runs through the design and construction phases and completes the cycle with the station's commissioning and connection to the UK electricity grid. To sum up, the Sizewell B project is a success story.

  9. The Sizewell B project

    International Nuclear Information System (INIS)

    The Sizewell B project has demonstrated the capability of the UK's manufacturing industry to undertake large projects and to meet the most demanding international standards - it is a triumph for the UK nuclear industry. The paper outlines the background to the decision to build Sizewell B, it runs through the design and construction phases and completes the cycle with the station's commissioning and connection to the UK electricity grid. To sum up, the Sizewell B project is a success story.

  10. Reviving Digital Projects

    Directory of Open Access Journals (Sweden)

    Nicole Scholtz

    2008-12-01

    Full Text Available What do you do when you are in charge of assessing and reviving an abandoned digital project you had no part in creating or implementing? This article will talk about the unique challenges and issues involved in such a project, drawing from a specific example at the University of Michigan Library. We contended with unfamiliar software, limited technical documentation, proprietary file formats and platform migration, and will discuss how we approached each of these specific technical issues. After reviving our project and reflecting on our process, we put together a list of guidelines that we feel will help assist others who may find themselves in similar situations.

  11. Making energy projects happen

    International Nuclear Information System (INIS)

    In today's business environment, control of energy cost is a major challenge for businesses, institutions, and governmental agencies. New technologies are available to reduce energy costs through cogeneration, cheaper fuels, or other means. Often it is not possible for a Plant Owner to undertake such a project, regardless of how desirable it may be. The authors of this paper show that by applying the principles of Project Structuring and developing a comprehensive project team, the desired reduction in energy costs can be achieved. Various examples are cited, and guidelines are given for an Owner to use

  12. The CORMAN project

    DEFF Research Database (Denmark)

    Bregnballe, Thomas

    2013-01-01

    The CORMAN project (‘Sustainable Management of Cormorant Populations’) is now in its final year. The main goals have been (1) to collaborate with the CRG in order to assess the number and distribution of Cormorants in Europe during breeding and wintertime, and (2) to create the EU Cormorant...... Platform in order to disseminate information. The project has also engaged with key European stakeholder groups and formed a Stakeholders Liaison Group to support information exchange and discuss relevant issues. The project is carried out on behalf of DG Environment under the European Commission....

  13. Managing Distributed Software Projects

    DEFF Research Database (Denmark)

    Persson, John Stouby

    and coordination in a successful, distributed software project between a Russian and a Danish company. The case study’s control aspects were investigated, drawing on Kirsch’s (2004) elements of control framework, to analyze how control is enacted in the project. This analysis showed that informal measurement...... showed that multimodal communication can facilitate collective minding in distributed software projects and can positively impact performance. In providing an approach for investigating the impact of multimodal communication practices on virtual team performance, we can further understand and support...

  14. Raspberry Pi projects

    CERN Document Server

    Robinson, Andrew

    2013-01-01

    Learn to build software and hardware projects featuring the Raspberry Pi! Raspberry Pi represents a new generation of computers that encourages the user to play and to learn and this unique book is aimed at the beginner Raspberry Pi user who is eager to get started creating real-world projects. Taking you on a journey of creating 15 practical projects, this fun and informative resource introduces you to the skills you need to have in order to make the most of the Pi. The book begins with a quick look at how to get the Pi up and running and then encourages you to dive into the array of exciti

  15. RESCON: Educational project scheduling software

    OpenAIRE

    Deblaere, Filip; Demeulemeester, Erik; Herroelen, Willy

    2011-01-01

    In this article we discuss a freely downloadable educational software tool for illustrating project scheduling and project management concepts. The tool features exact and heuristic scheduling procedures and visualizes project networks, project schedules, resource profiles, activity slacks, and project duration distributions.

  16. "Cheesy Pizza": The Pizza Project

    Science.gov (United States)

    Gallick, Barbara; Lee, Lisa

    2009-01-01

    A class of 3- to 5-year-old children in a midwestern child care center chose to study pizza restaurants as a group project. This article discusses how the project evolved, describes the three phases of the project, and provides the teachers' reflections on the project. Photos taken during the project and children's sketches are included. (Contains…

  17. Understanding Applications of Project Planning and Scheduling in Construction Projects

    OpenAIRE

    AlNasseri, Hammad Abdullah

    2015-01-01

    Construction project life-cycle processes must be managed in a more effective and predictable way to meet project stakeholders’ needs. However, there is increasing concern about whether know-how effectively improves understanding of underlying theories of project management processes for construction organizations and their project managers. Project planning and scheduling are considered as key and challenging tools in controlling and monitoring project performance, but many worldwide constru...

  18. Project Management in New Product Introduction Projects of a Company

    OpenAIRE

    Joenaho, Ilkka

    2016-01-01

    The success of projects is highly correlated to the way projects are managed. Project management is simply just an application of skills, tools, techniques and knowledge to project activities in a formal and systematic way. The company’s New Product Introduction projects have grown more complex over time and it has become necessary to evaluate current project management practices. The aim of this thesis was to study and evaluate the current state of New Product Introduction proje...

  19. Storytelling for project knowledge management across the project life cycle

    OpenAIRE

    Narges Farzaneh; Mehdi Shamizanjani

    2014-01-01

    Project organizations face the problems to manage knowledge embedded in various projects because of the uniqueness and short-term orientation of most projects. Therefore, project knowledge management is regarded as an important approach to building competitive advantages. This paper aimed to examine the application of storytelling as an effective and inexpensive mechanism for managing project knowledge. The study was conducted with the project management office from the Tax Administration and...

  20. Vitamin D Pooling Project

    Science.gov (United States)

    The Vitamin D Pooling Project of Rarer Cancers brought together investigators from 10 cohorts to conduct a large prospective epidemiologic study of the association between vitamin D status and seven rarer cancers.

  1. Tactile Communications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project has developed a set of tactile display garments that will be used to evaluate various tactile display methodologies. The garments include two sleeves...

  2. Aerospace Systems Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Phase I STTR project will demonstrate the Aerospace System Monitor (ASM). This technology transforms the power distribution network in a spacecraft or aircraft...

  3. LED projection displays

    Science.gov (United States)

    Lee, Won Yong; Lee, Young Chol; Sokolov, Kirill; Lee, Hee Joong; Moon, Il

    2004-09-01

    In this paper a new illumination system with high power light emitting diode (LED) sources for projection displays is proposed. The prototype of a rear projection system has been developed by using red, green and blue (RGB) LEDs and three LCD panels. Four LEDs were used for each primary color. Parabola reflectors were used for collimating the LED lights and a new array style of LEDs and collimators were used. Integration rods were directly used between collimators and LCD panels without relay lens for uniform light distribution. A 40" projection display system was made with a light output about 25 lm on the screen and the projection engine was very small comparing to the original engine which uses an arc source.

  4. DOE Robotics Project

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This document provide the bimonthly progress reports on the Department of Energy (DOE) Robotics Project by the University of Michigan. Reports are provided for the time periods of December 90/January 91 through June 91/July 91. (FI)

  5. Disruption Tolerant Networking Project

    Data.gov (United States)

    National Aeronautics and Space Administration — There are two parts to this project: technology development and technology demonstration and infusion into programs. The development of the DTN services is funded...

  6. Flight Systems Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase I project will develop the Flight System Monitor which will use non-intrusive electrical monitoring (NEMO). The electronic system health of...

  7. The SMILING project

    DEFF Research Database (Denmark)

    Berger, Jacques; Blanchard, Gentiane; Ponce, Maiza Campos;

    2013-01-01

    The "Sustainable Micronutrient Interventions to Control Deficiencies and Improve Nutritional Status and General Health in Asia" project (SMILING), funded by the European Commission, is a transnational collaboration of research institutions and implementation agencies in five Southeast Asian...

  8. Project Magnet 1996

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Project Magnet data include low altitude, high density individual track line surveys, high altitude vector data and regional magnetic anomaly grids.

  9. Distributed Project Work

    DEFF Research Database (Denmark)

    Borch, Ole; Kirkegaard, B.; Knudsen, Morten;

    1998-01-01

    Project work has been used for many years at Aalborg University to improve learning of theory and methods given in courses. In a closed environment where the students are forming a group in a single room, the interaction behaviour is more or less given from the natural life. Group work...... in a distributed fashion over the Internet needs more attention to the interaction protocol since the physical group room is not existing. The purpose in this paper is to develop a method for online project work by using the product: Basic Support for Cooperative Work (BSCV). An analysis of a well-proven protocol...... to be very precises and with success used on the second test group. Distributed project work is coming pretty soon and with little improvement in server tools, projects in different topics with a large and inhomogeneous profile of users are realistic....

  10. ALICE Time Projection Chamber

    CERN Multimedia

    Lippmann, C

    2013-01-01

    The Time Projection Chamber (TPC) is the main device in the ALICE 'central barrel' for the tracking and identification (PID) of charged particles. It has to cope with unprecedented densities of charges particles.

  11. Project Delivery Methods.

    Science.gov (United States)

    Dolan, Thomas G.

    2003-01-01

    Describes project delivery methods that are replacing the traditional Design/Bid/Build linear approach to the management, design, and construction of new facilities. These variations can enhance construction management and teamwork. (SLD)

  12. Water Properties Sensor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In this Phase I project, Kaitech proposes to design a Water Properties Sensor (WPS) sensing system to synchronously measure the spectral inherent and apparent...

  13. Water Properties Sensor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In this Phase II project, Kaitech proposes to develop and demonstrate a Water Properties Sensor (WPS) sensing system to synchronously measure the spectral inherent...

  14. Convergent Aeronautics Solutions Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Convergent Aeronautics Solutions (CAS) Project uses short-duration activities to establish early-stage concept and technology feasibility for high-potential...

  15. Principles of project management

    Science.gov (United States)

    1982-01-01

    The basic principles of project management as practiced by NASA management personnel are presented. These principles are given as ground rules and guidelines to be used in the performance of research, development, construction or operational assignments.

  16. Health System Measurement Project

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Health System Measurement Project tracks government data on critical U.S. health system indicators. The website presents national trend data as well as detailed...

  17. Lake Charles CCS Project

    Energy Technology Data Exchange (ETDEWEB)

    Leib, Thomas [Leucadia Energy, LLC, Salt Lake City, UT (United States); Cole, Dan [Denbury Onshore, LLC, Plano, TX (United States)

    2015-06-30

    In late September 2014 development of the Lake Charles Clean Energy (LCCE) Plant was abandoned resulting in termination of Lake Charles Carbon Capture and Sequestration (CCS) Project which was a subset the LCCE Plant. As a result, the project was only funded through Phase 2A (Design) and did not enter Phase 2B (Construction) or Phase 2C (Operations). This report was prepared relying on information prepared and provided by engineering companies which were engaged by Leucadia Energy, LLC to prepare or review Front End Engineering and Design (FEED) for the Lake Charles Clean Energy Project, which includes the Carbon Capture and Sequestration (CCS) Project in Lake Charles, Louisiana. The Lake Charles Carbon Capture and Sequestration (CCS) Project was to be a large-scale industrial CCS project intended to demonstrate advanced technologies that capture and sequester carbon dioxide (CO2) emissions from industrial sources into underground formations. The Scope of work was divided into two discrete sections; 1) Capture and Compression prepared by the Recipient Leucadia Energy, LLC, and 2) Transport and Sequestration prepared by sub-Recipient Denbury Onshore, LLC. Capture and Compression-The Lake Charles CCS Project Final Technical Report describes the systems and equipment that would be necessary to capture CO2 generated in a large industrial gasification process and sequester the CO2 into underground formations. The purpose of each system is defined along with a description of its equipment and operation. Criteria for selection of major equipment are provided and ancillary utilities necessary for safe and reliable operation in compliance with environmental regulations are described. Construction considerations are described including a general arrangement of the CCS process units within the overall gasification project. A cost estimate is provided, delineated by system area with cost breakdown showing equipment, piping and materials

  18. The Kintyre uranium project

    International Nuclear Information System (INIS)

    The Kintyre Uranium Project is being developed by Canning Resources Pty Ltd, a subsidiary of Rio Tinto (formerly CRA). The work on the project includes the planning and management of a number of background environmental studies. The company has also commissioned studies by external consultants into process technologies, mining strategies and techniques for extracting the uranium ore from the waste rock. In addition, Canning Resources has made a detailed assessment of the worldwide market potential for Australian uranium in the late 1990s and into the 21st century. The most significant factor affecting the future of this project is the current product price. This price is insufficient to justify the necessary investment to bring this project into production

  19. Core Flight Software Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The mission of the CFS project is to provide reusable software in support of human space exploration programs.   The top-level technical approach to...

  20. Mitigation : Closed Basin Project

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The upcoming meeting on waterfowl mitigation for the Closed Basin Project will have several people talk about possible changes to the waterfowl mitigation program....

  1. Spacecraft Power Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase I project will develop the Spacecraft Power Monitor (SPM) which will use non-intrusive electrical monitoring (NEMO). NEMO transforms the power...

  2. Project Planningmeasures in CMMI

    Directory of Open Access Journals (Sweden)

    Mahmoud Khraiwesh

    2013-04-01

    Full Text Available Computer information project planning is one of the most important activities in the modern softwaredevelopment process. Without an objective and realistic plan of software project, the development ofsoftware process cannot be managed effectively.Thisresearchwill identify general measures for thespecific goals and its specific practices of Project PlanningProcess Area in Capability Maturity ModelIntegration (CMMI. CMMI is developedin USAby Software Engineering Institute (SEI inCarnegieMellonUniversity. CMMI is a framework for assessment and improvement of computer informationsystems. The procedure we used to determine the measures is to apply the Goal Questions Metrics (GQMapproach to the three specific goals and its fourteen specific practices of Project PlanningProcess Area inCMMI

  3. TESLA project goes public

    CERN Document Server

    Flegel, I

    2001-01-01

    The DESY laboratory in Hamburg recently published plans for a superconducting linear electron-positron collider: TESLA. This article amplifies these ambitious plans and outlines the objectives of the project. (0 refs).

  4. Infrared Detectors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The end goal of this project is to develop proof-of-concept infrared detectors which can be integrated in future infrared instruments engaged in remote...

  5. Wind project gets boost

    Energy Technology Data Exchange (ETDEWEB)

    Oirere, Shem

    2012-11-01

    The development of a two-phase 100 MW wind power plant project in Tanzania moved a notch higher this year when Export-Import Bank of China extended a US$ 123 million non-concessional loan for its construction.

  6. Current Resource Imagery Projects

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — Map showing coverage of current Resource imagery projects. High resolution/large scale Resource imagery is typically acquired for the U.S. Forest Service and other...

  7. OECD: Halden reactor project

    International Nuclear Information System (INIS)

    The work at the Project has continued in the two main fields: test fuel irradiation and fuel research, and computer based process supervision and control. Organizations participating in the Project continue to have their fuel irradiated in the Halden Reactor in instrumented test assemblies designed and manufactured by the Project. The Project's fuel studies continue to focus on specific subjects such as fuel pellet/cladding interaction and heat transfer, fission product release and fuel behavior under loss of coolant conditions. The work on process control and supervision continues in the highly relevant fields of core control and operator-process communication. A system for predictive core control is being developed while special mathematical methods for core power distribution control are being studied. Operator-process communication studies comprise use of computer simulation on colour display as important ingredients, while the work on developing a system for interactive plant disturbance analysis continues

  8. OpenCities Project

    Data.gov (United States)

    US Agency for International Development — The Open Cities Project aims to catalyze the creation, management and use of open data to produce innovative solutions for urban planning and resilience challenges...

  9. Configurable Project Collaboration Portal

    Data.gov (United States)

    National Aeronautics and Space Administration — SplashNote Systems is proposing to develop a more effective and innovative approach to project collaboration in distributed teams. The proposed system uniquely...

  10. 3D Projection Installations

    DEFF Research Database (Denmark)

    Halskov, Kim; Johansen, Stine Liv; Bach Mikkelsen, Michelle

    2014-01-01

    Three-dimensional projection installations are particular kinds of augmented spaces in which a digital 3-D model is projected onto a physical three-dimensional object, thereby fusing the digital content and the physical object. Based on interaction design research and media studies, this article...... contributes to the understanding of the distinctive characteristics of such a new medium, and identifies three strategies for designing 3-D projection installations: establishing space; interplay between the digital and the physical; and transformation of materiality. The principal empirical case, From...... Fingerplan to Loop City, is a 3-D projection installation presenting the history and future of city planning for the Copenhagen area in Denmark. The installation was presented as part of the 12th Architecture Biennale in Venice in 2010....

  11. The WPU Project

    DEFF Research Database (Denmark)

    Jensen, Janne Jul; Skov, Mikael B.; Stage, Jan

    2008-01-01

    The Web Portal Usability (WPU) project focuses on usability in the development of modern web portals. Web portals are a key part of software development. They are created to provide a group of users with access to a collection of internet services. State-of-the-art methods for usability engineering...... in the course of the project, when there is neither time nor financial possibilities for solving the problems. The objective of the WPU project is to develop new methods for usability engineering in the development of web portals and to test these methods in companies that develop modern web portals. The result...... is a catalogue of methods that support usability engineering in web portal development, combined with guidelines for use, training programmes and documented experience from deployment and use of the methods. The WPU project is a collaborative effort between researchers from Aalborg University, Department...

  12. Navajo Electrification Demonstraiton Project

    Energy Technology Data Exchange (ETDEWEB)

    Larry Ahasteen, Project Manager

    2006-07-17

    This is a final technical report required by DOE for the Navajo Electrification Demonstration Program, This report covers the electric line extension project for Navajo families that currently without electric power.

  13. Prioritising Project Scope Definition Elements in Public Building Projects

    Directory of Open Access Journals (Sweden)

    Mohammed K Fageha

    2014-09-01

    Full Text Available A complete definition of the scope of a project upfront during early stages ensures smooth and successful implementation during the project execution. This research identifies and prioritises project scope definition elements for public buildings in Saudi Arabia. Elements that could significantly contribute to complete project scope definition package at pre-project planning stage are identified and their interrelationship determined and prioritised. Using the Project Definition Rating Index (PDRI as a basis, the study uses analytical network process (ANP technique based on data obtained from project managers who have been involved in public sector projects in Saudi Arabia. Data collection and analysis was conducted in three steps. The first step involved identification of scope definition elements while the second involved an investigation into interrelationships among the elements. In the third step, ANP was used to determine the weight of the elements’ importance in terms of contribution to project scope definition completeness. Finally, Pareto analysis was used to prioritise and assess the distribution pattern of the elements. The outcome from this research is the prioritisation of project scope definition elements for public building projects in Saudi Arabia. The prioritised list developed indicates the importance of project scope definition elements. It should help project management teams identify elements to consider when evaluating project scope definition for completeness at the pre-project planning stage. Keywords: Project scope definition, pre-project planning, prioritising, public building projects, Saudi Arabia, Analytical Network Process (ANP

  14. BODIES OF KNOWLEDGE IN PROJECT MANAGEMENT AND PROJECT QUALITY MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Tamara Gvozdenovic

    2008-03-01

    Full Text Available One of the main trends is standardization of project management. Some of the most important bodies of knowledge in project management, which were created by professional associations for project management are given in this paper. The main of the project management, apart from minimization of time, resources and costs, is to finish the project in the required quality, i.e. it is very important during the whole process of project management to provide realizing the project without any deviations from the previously set quality standards. Basic processes of project quality management are: quality planning, quality assurance and quality control.

  15. Project X Broader Impacts

    CERN Document Server

    Asner, D M; Henderson, S; Plunkett, R; Wootan, D W; Peterson, M A; Senor, D; Tschirhart, R; Grasselino, A; Romanenko, A; MacDougall, G; Heffner, R H

    2013-01-01

    Part-3 of "Project X: Accelerator Reference Design, Physics Opportunities, Broader Impacts". The proposed Project X proton accelerator at Fermilab, with multi-MW beam power and highly versatile beam formatting, will be a unique world-class facility to explore particle physics at the intensity frontier. Concurrently, however, it can also facilitate important scientific research beyond traditional particle physics and provide unprecedented opportunities in applications to problems of great national importance in the nuclear energy and security sector.

  16. Project X: Physics Opportunities

    CERN Document Server

    Kronfeld, Andreas S; Al-Binni, Usama; Altmannshofer, Wolfgang; Ankenbrandt, Charles; Babu, Kaladi; Banerjee, Sunanda; Bass, Matthew; Batell, Brian; Baxter, David V; Berezhiani, Zurab; Bergevin, Marc; Bernstein, Robert; Bhattacharya, Sudeb; Bishai, Mary; Blum, Thomas; Bogacz, S Alex; Brice, Stephen J; Brod, Joachim; Bross, Alan; Buchoff, Michael; Burgess, Thomas W; Carena, Marcela; Castellanos, Luis A; Chattopadhyay, Subhasis; Chen, Mu-Chun; Cherdack, Daniel; Christ, Norman H; Chupp, Tim; Cirigliano, Vincenzo; Coloma, Pilar; Coppola, Christopher E; Cowsik, Ramanath; Crabtree, J Allen; Delahaye, Jean-Pierre; Denisov, Dmitri; deNiverville, Patrick; de Gouvêa, André; Dharmapalan, Ranjan; Dolgov, Alexander; Dvali, Georgi; Eichten, Estia; Engelfried, Jürgen; Ferguson, Phillip D; Gabriel, Tony; Gal, Avraham; Gallmeier, Franz; Ganezer, Kenneth S; Gardner, Susan; Glenzinski, Douglas; Godfrey, Stephen; Golubeva, Elena S; Gori, Stefania; Graves, Van B; Greene, Geoffrey; Griffard, Cory L; Haisch, Ulrich; Handler, Thomas; Hartfiel, Brandon; Hawari, Ayman; Heilbronn, Lawrence; Hill, James E; Huber, Patrick; Jaffe, David E; Johnson, Christian; Kamyshkov, Yuri; Kaplan, Daniel M; Kerbikov, Boris; Kiburg, Brendan; Kirk, Harold G; Klein, Andreas; Knoepfel, Kyle; Kopeliovich, Boris; Kopeliovich, Vladimir; Kopp, Joachim; Korsch, Wolfgang; Kribs, Graham; Lipton, Ronald; Liu, Chen-Yu; Lorenzon, Wolfgang; Lu, Zheng-Tian; Makins, Naomi C R; McKeen, David; Mills, Geoffrey; Mohapatra, Rabindra; Mokhov, Nikolai V; Mocko, Michael; Muhrer, Guenter; Mumm, Pieter; Okun, Lev; Neuffer, David; Palmer, Mark A; Palmer, Robert; Pattie, Robert W; Phillips, David G; Pronsikh, Vitaly; Pitts, Kevin; Pospelov, Maxim; Quigg, Chris; Ramberg, Erik; Ray, Amlan; Reimer, Paul E; Richards, David G; Ritz, Adam; Roy, Amit; Ruggles, Arthur; Ryne, Robert; Sarkar, Utpal; Saunders, Andy; Semertzidis, Yannis K; Serebrov, Anatoly; Shimizu, Hirohiko; Shrock, Robert; Snopok, Pavel V; Snow, William M; Sikdar, Arindam K; Soha, Aria; Spanier, Stefan; Striganov, Sergei; Tang, Zhaowen; Townsend, Lawrence; Urheim, Jon; Vainshtein, Arkady; Van Kooten, Richard J; Van de Water, Richard; Van de Water, Ruth S; Wehring, Bernard; Whitehead, Lisa; Wilson, Robert J; Worcester, Elizabeth; Young, Albert R; Wester, William C; Zeller, Geralyn

    2013-01-01

    Part 2 of "Project X: Accelerator Reference Design, Physics Opportunities, Broader Impacts". In this Part, we outline the particle-physics program that can be achieved with Project X, a staged superconducting linac for intensity-frontier particle physics. Topics include neutrino physics, kaon physics, muon physics, electric dipole moments, neutron-antineutron oscillations, new light particles, hadron structure, hadron spectroscopy, and lattice-QCD calculations.

  17. Project Bog Turtle

    OpenAIRE

    North Carolina Herpetological Society

    2007-01-01

    Project Bog Turtle South was started by the Conservation Committee of the North Carolina Herpetological Society in 1995 to protect the bog turtle and its habitat throughout the southeastern US. This is being done through leases, purchases or easements on bog turtle habitats, habitat restoration, scientific research, and education. The project is currently providing bog turtle protection for six sites in the Georgia and North Carolina areas.

  18. The AFP Project

    CERN Document Server

    Staszewski, R

    2011-01-01

    AFP is a project to extend the diffractive physics programme of the ATLAS experiment by installing new detectors that will be able to tag forward protons scattered at very small angles. This will allow us to study Single Diffraction, Double Pomeron Exchange, Central Exclusive Production and photon-photon processes. This note presents the physics case for the AFP project and briefly describes the proposed detector system.

  19. The Multimedia Project Quarked!

    OpenAIRE

    Bean, Alice; MacDonald, Teresa

    2011-01-01

    Can exposure to fundamental ideas about the nature of matter help motivate children in math and science and support the development of their understanding of these ideas later? Physicists, designers, and museum educators at the University of Kansas created the Quarked!(tm) Adventures in the subatomic Universe project to provide an opportunity for youth to explore the subatomic world in a fun and user friendly way. The project components include a website (located at http://www.quarked.org) an...

  20. Raspberry Pi robotics projects

    CERN Document Server

    Grimmett, Richard

    2015-01-01

    This book is for enthusiasts who want to use the Raspberry Pi to build complex robotics projects. With the aid of the step-by-step instructions in this book, you can construct complex robotics projects that can move, talk, listen, see, swim, or fly. No previous Raspberry Pi robotics experience is assumed, but even experts will find unexpected and interesting information in this invaluable guide.

  1. The human genome project

    International Nuclear Information System (INIS)

    The Human Genome Project is a massive international research project, costing 3 to 5 billion dollars and expected to take 15 years, which will identify the all the genes in the human genome - i.e. the complete sequence of bases in human DNA. The prize will be the ability to identify genes causing or predisposing to disease, and in some cases the development of gene therapy, but this new knowledge will raise important ethical issues

  2. The Bruce nuclear project

    International Nuclear Information System (INIS)

    This case study assesses the industrial relations impact of the construction of the Bruce Nuclear Power Development. It examines the labour relations system in the Ontario electric power sector and in major building construction. Industrial relations problems and practices at the Bruce project are reviewed. The focus of the study is on the relationship between the project and the rest of the Ontario industrial construction industry

  3. 6 Sigma project advance

    International Nuclear Information System (INIS)

    This book deals with 6 sigma project advance which introduces 6 sigma project in Changwon special steel, how is failure accepted? CTQ selection which is starting line, definition of performance standard, measurement system check on reliability of measurement data, check of process capacity for current level, establishment of target, optimal design and performance of application, practice of management system for maintain of improved result, CTQ selection, check of measurement system and practice of management system.

  4. The WPU Project

    DEFF Research Database (Denmark)

    Jensen, Janne Jul; Skov, Mikael B.; Stage, Jan

    2009-01-01

    The Web Portal Usability (WPU) project is working on usability engineering methods, which are important in the development of Web portals. These methods are tested with companies that design modern Web portals.......The Web Portal Usability (WPU) project is working on usability engineering methods, which are important in the development of Web portals. These methods are tested with companies that design modern Web portals....

  5. The Mississippi CCS Project

    Energy Technology Data Exchange (ETDEWEB)

    Doug Cathro

    2010-09-30

    The Mississippi CCS Project is a proposed large-scale industrial carbon capture and sequestration (CCS) project which would have demonstrated advanced technologies to capture and sequester carbon dioxide (CO{sub 2}) emissions from industrial sources into underground formations. Specifically, the Mississippi CCS Project was to accelerate commercialization of large-scale CO{sub 2} storage from industrial sources by leveraging synergy between a proposed petcoke to Substitute Natural Gas (SNG) plant that is selected for a Federal Loan Guarantee and would be the largest integrated anthropogenic CO{sub 2} capture, transport, and monitored sequestration program in the U.S. Gulf Coast Region. The Mississippi CCS Project was to promote the expansion of enhanced oil recovery (EOR) in the Mississippi, Alabama and Louisiana region which would supply greater energy security through increased domestic energy production. The capture, compression, pipeline, injection, and monitoring infrastructure would have continued to sequester CO{sub 2} for many years after the completion of the term of the DOE agreement. The objectives of this project were expected to be fulfilled through two distinct phases. The overall objective of Phase 1 was to develop a fully definitive project basis for a competitive Renewal Application process to proceed into Phase 2 - Design, Construction and Operations. Phase 1 included the studies that establish the engineering design basis for the capture, compression and transportation of CO{sub 2} from the MG SNG Project, and the criteria and specifications for a monitoring, verification and accounting (MVA) plan at the Soso oil field in Mississippi. The overall objective of Phase 2, was to execute design, construction and operations of three capital projects: the CO{sub 2} capture and compression equipment, the Mississippi CO{sub 2} Pipeline to Denbury's Free State Pipeline, and an MVA system at the Soso oil field.

  6. SEARCH Project Delphi

    OpenAIRE

    Tanja Sinozic

    2012-01-01

    This paper describes a plan to implement the Delphi method to obtain consensus of expert opinions on policy statements derived from research evidence. The evidence is based on a three-year large-scale European Union (EU) research project ("SEARCH"). The SEARCH project focuses on trade, migration, innovation and institutional issues on relationships between the European Union (EU) and its neighbouring countries (NCs). The main objective of the use of Delphi in this context is to...

  7. The Jigsaw Mural Project

    Science.gov (United States)

    Neelon, Caleb; Crawford, Jodi

    2004-01-01

    The Jigsaw Mural Project provides a way for young children to work on a large-scale and permanent mural, in a manner that allows them to work on the floor and without the use of ladders. It is also a chance for art educators to work with students as teacher and collaborator in one. This project took place with preschool children ages two through…

  8. Nuclear safety project

    International Nuclear Information System (INIS)

    The semiannual progress report 1984/1 is a description of work within the Nuclear Safety Project performed in the first six month of 1984 in the nuclear safety field by KfK institutes and departements and by external institutions on behalf of KfK. The chosen kind of this report is that of short summaries, containing the topics work performed, results obtained and plans for future work. This report was compiled by the project management. (orig./RW)

  9. The Happiness Project

    OpenAIRE

    Hansen, Maria Skadkær; Kristiansen, Mikkel Bjelke; Pinhasi, Tami; Ursin, Malte Grane; Larsen, Tim Kistrup; Manganga, Eric; Christensen, Jonas Juhl; Kløvedal, Sille Freydis Hagerup

    2008-01-01

    In this project several theories of happiness will be discussed in order to determine which one provides the fullest explanation. Part of the motivation for this project is a request by the TitiBo group which is an organisation that works to increase happiness in children aged three to five in kindergartens and day care institutions. Different forms of happiness will be evaluated such as eudaimonia and hedonia, which are long term and short term respectively. The terms subjective and psycholo...

  10. Projection and registration device

    OpenAIRE

    Verlinden, J.C.

    2009-01-01

    A projection and recording device, provided with a processing and control unit, a memory for recording images and other data, an input/output interface, a controllable camera, a touch screen for the input and display of data and images, a position determining system for determining the position of at least one object in relation to the projection and recording device, with images recorded by the camera being storable in the memory and displayable on the touch screen, and a projector for proje...

  11. Project Nuclear Safety

    International Nuclear Information System (INIS)

    The semiannual progress report 1981/1 is a description of work within the Nuclear Safety Project performed in the first six month of 1981 in the nuclear safety field by KfK institutes and departments and by external institutions on behalf of KfK. The chosen kind of this report is that of short summaries, containing the topics, work performed, results obtained, plans for future work. This report was compiled by the project management. (orig.)

  12. Mexico environmental services project

    OpenAIRE

    Comisión Nacional Forestal (CONAFOR)

    2007-01-01

    Metadata only record The Mexico Environmental Services Project aims to improve water quality, biodiversity, and carbon sequestration from areas with globally significant biodiversity. Eight pilot sites will be chosen to overlap with existing high-priority biodiversity conservation areas. The project objectives will be met through "(i) strengthening the capacity of CONAFOR, INE, community associations, and NGOs to increase flexibility and improve efficiency of existing service provision to ...

  13. Data Archive Project

    OpenAIRE

    Kemppainen, Timo-Pekka

    2015-01-01

    In the modern world, digital data archiving and accessing is an issue that needs tailored solutions. This thesis gives one example of designing and implementing a data archiving solution using time tested technologies. Helsinki Metropolia University of Applied Sciences had a need to archive their contracts in digital format instead of using old file cabinets. Specifications were created together with the customer at the start of the project. The project was to produce a complete product fo...

  14. Environmental Management within Projects

    OpenAIRE

    Ying He

    2009-01-01

    The role of environmental management within projects is playing a more and more essential part to the firms and public. Because of the benefit of implementing environmental management, different methods are being used to improveenvironmental management in projects especially in industry. However, the application of these methods leads to an increase in labor use, materials costs and other costs, which can limit their implementation. This paper provides the benefits and the barriers to the imp...

  15. The international hydrocoin project

    International Nuclear Information System (INIS)

    The International HYDROCOIN (Hydrologic Code Intercomparison) Project was started in May 1984. Fourteen organizations participate in the Project, with the Swedish Nuclear Power Inspectorate (SKI) as managing participant and the OECD Nuclear Energy Agency (NEA) taking part as a member of the Project secretariat. HYDROCOIN is concerned with the assessment of groundwater movements at potential nuclear waste disposal sites with the help of mathematical models and computer codes. The Project is divided into three levels. The objective of HYDROCOIN Level 1 is to verify the accuracy of groundwater flow codes. HYDROCOIN Level 2 and Level 3 are concerned with validation of hydrological models and uncertainty/sensitivity analysis, respectively. This report, which has been prepared by the NEA Secretariat and SKI in consultation with the co-ordinating group of the HYDROCOIN Project summarizes the background and objectives of the Project and presents the results of the work performed up to the middle of 1987. It is intended to provide general information on HYDROCOIN to interested parties beyond the group of directly involved specialists

  16. The international Chernobyl project

    International Nuclear Information System (INIS)

    This article summarizes the official report of the International Advisory Committee at the conference of the International Chernobyl Project held in Vienna, May 1991. More details will be found in the actual report, ''The International Chernobyl Project: An Overview'' (INI22:066284/5). Measurements and assessments carried out under the project provided general corroboration of the levels of surface cesium-137 contamination reported in the official maps. The project also concluded that the official procedures for estimating radiation doses to the population were scientifically sound, although they generally resulted in overestimates of two- to threefold. The project could find no marked increase in the incidence of leukemia or cancer, but reported absorbed thyroid doses in children might lead to a statistically detectable rise in the incidence of thyroid tumors. Significant non-radiation-related health disorders were found, and the accident had substantial psychological consequences in terms of anxiety and stress. The project concluded that the protective measures taken were too extreme, and that population relocation and foodstuff restrictions should have been less extensive

  17. Project Radiation Protection - East

    International Nuclear Information System (INIS)

    The Swedish Government has allocated SEK 37.1 million for cooperation projects in radiation protection with countries in Central and Eastern Europe, particularly the Baltic states (Estonia, Latvia, Lithuania) and Russia. The Swedish Radiation Protection Inst. (SSI) is in charge of this program, which is often referred to as Radiation Protection - East. The general background of this cooperation program, its objectives, practical organization of the work etc. have been presented in the following reports: SSI Report No.93-08: Projekt Straalskydd Oest - Laegesrapport (March 1993); SSI Report No.93-29: Swedish Cooperation Program for Radiation Protection in Eastern and Central Europe (November 1993). The present report summarizes the work carried out up to and including September 1994. The more than 70 cooperation projects have been divided into the following categories: Upgrading of national authorities; Emergency preparedness, early warning; Nuclear power and research reactors; Instrumentation; Decommissioning, waste, environmental control; General radiation protection; Other projects; Project management and administrative support. Project criteria and a simple program for quality assurance and follow-up are presented briefly. A status report, including an economic overview, is given for all ongoing or already finished projects, together with future plans and a suggested budget for the next fiscal year

  18. PrePARe project blog

    OpenAIRE

    PrePARe project team

    2012-01-01

    The JISC-funded PrePARe project aimed to encourage researchers to take an interest and responsibility in digital preservation of their research outputs. This is a preservation copy of the Project blog documenting the project progress.

  19. Successful Corporate ID Project Management.

    Science.gov (United States)

    Liang, Chaoyun Chaucer; Schwen, Thomas M.

    1999-01-01

    Provides a literature review on project management related to corporate instructional design activities. Highlights include project integration, strategic planning, resource allocation, optimizing performance and quality, constructing a project team, generating a productive working climate, and implementation strategies. (LRW)

  20. Murine partial-body radiation exposure model for biodosimetry studies - Preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Blakely, William F., E-mail: blakely@afrri.usuhs.mil [Uniformed Services University, Armed Forces Radiobiology Research Institute, Scientific Research Department, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603 (United States); Sandgren, David J., E-mail: Sandgren@afrri.usuhs.mil [Uniformed Services University, Armed Forces Radiobiology Research Institute, Scientific Research Department, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603 (United States); Nagy, Vitaly, E-mail: nagy@afrri.usuhs.mil [Uniformed Services University, Armed Forces Radiobiology Research Institute, Scientific Research Department, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603 (United States); Kim, Sung-Yop, E-mail: kimy@afrri.usuhs.mil [Uniformed Services University, Armed Forces Radiobiology Research Institute, Scientific Research Department, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603 (United States); Ossetrova, Natalia I., E-mail: ossetrova@afrri.usuhs.mil [Uniformed Services University, Armed Forces Radiobiology Research Institute, Scientific Research Department, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603 (United States)

    2011-09-15

    The objective of the present study was to establish a murine partial-body radiation exposure model for studies supporting the identification and validation of novel biological dosimetry diagnostic assays. A lead shielding - Plexiglas irradiation apparatus with cutouts to permit irradiation of single-mouse-holder constrained CD2F1 male mice to total-body (3/3), mid- and lower-body (2/3), mid-body only (1/3), and 100% lead shielding sham-treated (0 Gy) controls (0/3) with a 250-kVp X-ray source (dose: 6 Gy, dose rate: 0.50 Gy min{sup -1}) was used. Doses and dose uniformity were measured using alanine - electron paramagnetic resonance (EPR) and ionization chambers. Dosimetry mapping results showed {approx}2 and {approx}12% non-uniformity in the radiation fields for the two smaller (1/3, 2/3) and one larger (3/3) fields, respectively. Hematology results showed no marked differences in neutrophil and platelet counts 1 and 2 days (d) after irradiation. The lymphocyte counts, as expected, demonstrate a progressive decline below baseline levels 1 and 2 d after irradiation with increasing fraction of the body exposed, while the neutrophil to lymphocyte ratios show the inverse effect, with a progressive increase with the fraction of body exposed. The bone marrow biomarker, Flt3 ligand, demonstrated a progressive increase in values with increasing fraction of the body exposed; the 2 d response was enhanced compared to 1 d. The radioresponse 1 d after irradiation for the acute phase reactant protein biomarker, serum amyloid A (SAA) that is synthesized by the liver, was significantly influenced depending on whether the mouse head was in the radiation field. Use of multiple biomarkers based on hematology and proteomic targets provide an enhancement in early-phase partial-body radiation exposure assessment.