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Sample records for biochim biophys acta

  1. Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica is an accredited, South African journal publishing independently reviewed research articles on broad Christian-theological and religion topics, aimed at a national and international academic audience/readership. The Editorial Board accepts and considers for possible publication articles in English and ...

  2. Acta Structilia

    African Journals Online (AJOL)

    Acta Structilia Journal is a South African accredited national journal for independently adjudicated research articles on any topic in the field of the physical and development sciences on subjects in any applicable field of scholarship, i.e. architecture, urban and regional planning, quantity surveying, construction management ...

  3. 12038_2016_9643_Article_print 577..588

    Indian Academy of Sciences (India)

    2016-10-14

    -Bayat Z, Hosseinkhani S, Jafari R and Khajeh K 2012. Relationship between stability and flexibility in the most flexible region of Photinus pyralis luciferase. Biochim. Biophys. Acta. (BBA) Proteins Proteomics. 1824 350–358.

  4. Disease: H00419 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ... Garg A, Agarwal AK ... TITLE ... Lipodystrophies: disorders of adipose tissue biology. ... JOURNAL ... Biochim Biophys Acta 1791:507-13 (2009) DOI:10.1016/j.bbalip.2008.12.014 ...

  5. Archives: Acta Structilia

    African Journals Online (AJOL)

    Items 1 - 14 of 14 ... Archives: Acta Structilia. Journal Home > Archives: Acta Structilia. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 14 of 14 Items. 2017. Vol 24, No 2 (2017) ...

  6. Bibliography | Ito | Acta Theologica

    African Journals Online (AJOL)

    Abstract. Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015.

  7. Acknowledgements | Ito | Acta Theologica

    African Journals Online (AJOL)

    Abstract. Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015.

  8. Acta Genetica Sinica (Selected Articles),

    Science.gov (United States)

    1986-04-04

    0879-8SF/ /3 N IT 0󈧬 112. MIRCK L~~Nj~ %. *- - - - - - - - -I.. * .. - II , I FTD-ID(RS)T-0879-85 oM FOREIGN TECHNOLOGY DIVISION ACTA GENETICA SINICA...34 ’ ° ° ° !4 :A.. it.i FTD- ID(RS)T-0879-85 HUMAN TRANSLATION FTD-ID(RS)T-0879-85 4 April 1986 MICROFICHE NR: FTD-86-C-001691 ACTA GENETICA SINICA...merged into this translation were extracted from the best quality copy available. •i 12 (2): 93-101, 1985 Yichuan Xuebao (Acta Genetica Sinica) Genetic

  9. Applications of the BIOPHYS Algorithm for Physically-Based Retrieval of Biophysical, Structural and Forest Disturbance Information

    Science.gov (United States)

    Peddle, Derek R.; Huemmrich, K. Fred; Hall, Forrest G.; Masek, Jeffrey G.; Soenen, Scott A.; Jackson, Chris D.

    2011-01-01

    Canopy reflectance model inversion using look-up table approaches provides powerful and flexible options for deriving improved forest biophysical structural information (BSI) compared with traditional statistical empirical methods. The BIOPHYS algorithm is an improved, physically-based inversion approach for deriving BSI for independent use and validation and for monitoring, inventory and quantifying forest disturbance as well as input to ecosystem, climate and carbon models. Based on the multiple-forward mode (MFM) inversion approach, BIOPHYS results were summarized from different studies (Minnesota/NASA COVER; Virginia/LEDAPS; Saskatchewan/BOREAS), sensors (airborne MMR; Landsat; MODIS) and models (GeoSail; GOMS). Applications output included forest density, height, crown dimension, branch and green leaf area, canopy cover, disturbance estimates based on multi-temporal chronosequences, and structural change following recovery from forest fires over the last century. Good correspondences with validation field data were obtained. Integrated analyses of multiple solar and view angle imagery further improved retrievals compared with single pass data. Quantifying ecosystem dynamics such as the area and percent of forest disturbance, early regrowth and succession provide essential inputs to process-driven models of carbon flux. BIOPHYS is well suited for large-area, multi-temporal applications involving multiple image sets and mosaics for assessing vegetation disturbance and quantifying biophysical structural dynamics and change. It is also suitable for integration with forest inventory, monitoring, updating, and other programs.

  10. Purification and molecular cloning of a new galactose-specific lectin ...

    Indian Academy of Sciences (India)

    Srinivas

    2. Materials and methods. 2.1 Plant material. All experiments were carried out with B. variegata seeds collected from plants grown in the state of São Paulo, ..... lectin structure; Biochim. Biophys. Acta 1383 9–36. Macedo M L R, Freire M G M, Silva M B R and Coelho LCBB 2007. Insecticidal action of Bauhinia monandra leaf ...

  11. Efficacious Oxime for Organophosphorus Poisoning: A Minireview

    African Journals Online (AJOL)

    Erah

    Wilson IB, Ginsburg SA. Powerful reactivator of alkyl phosphate inhibited acetylcholinesterase. Biochim Biophys Acta 1955; 18: 168-170. 13. Namba T, Hiraki K. PAM (pyridine-2-aldoxime methiodide) therapy for alkyl-phosphate poisoning. J Am Med Assoc 1958; 166: 1834-. 1839. 14. Antonijevic B, Stojijkovic MP. Unequal ...

  12. Generation of specific deoxynojirimycin-type inhibitors of the non-lysosomal glucosylceramidase

    NARCIS (Netherlands)

    Overkleeft, H. S.; Renkema, G. H.; Neele, J.; Vianello, P.; Hung, I. O.; Strijland, A.; van der Burg, A. M.; Koomen, G. J.; Pandit, U. K.; Aerts, J. M.

    1998-01-01

    The existence of a non-lysosomal glucosylceramidase in human cells has been documented (van Weely, S., Brandsma, M., Strijland, A., Tager, J. M., and Aerts, J. M. F. G. (1993) Biochim. Biophys. Acta 1181, 55-62). Hypothetically, the activity of this enzyme, which is localized near the cell surface,

  13. Leucine zipper transcription factor-like 1 expression in gastric ...

    African Journals Online (AJOL)

    Pinho SS, Seruca R, Gärtner F, Yamaguchi Y, Gu J,. Taniguchi N, Reis CA. Modulation of E-cadherin function and dysfunction by N-glycosylation. Cell Mol Life Sci. 2011; 68(6): 1011-1020. 11. Rodriguez FJ, Lewis-Tuffin LJ, Anastasiadis PZ. E- cadherin's dark side: possible role in tumor progression. Biochim Biophys Acta ...

  14. Fulltext PDF

    Indian Academy of Sciences (India)

    Prakash

    of chlorobiumquinone in the transplasma membrane electron transport system of Leishmania donovani promastigote: effect of near-ultraviolet light on the redox reaction of plasma membrane; Biochim. Biophys. Acta 1780 116–127. Brar S S, Kennedy T P, Whorton A R, Sturrock A B, Huecksteadt. T P, Ghio A J and Hoidal J R ...

  15. Effect of Drugs on the Lethality in Mice of the Venoms and Neurotoxins from Sundry Snakes

    Science.gov (United States)

    1990-07-10

    phospholipase A9 on bilayers: effect of inhibitors. Biochim. biophys. Acta 814, 319-326. KARLSSON, E. (1979) Chemistry of protein toxins in snake...bungarotoxin (A), followed immediately by a separate injection of various doses of verapamil. Tesi of overall significance, % of control mice surviving: B

  16. ETS Gene Fusions as Predictive Biomarkers of Resistance to Radiation Therapy for Prostate Cancer

    Science.gov (United States)

    2011-08-01

    cancers. Biochim. Biophys. Acta 1796, 201–215. Bryant, H.E., Schultz, N., Thomas , H.D., Parker, K.M., Flower, D., Lopez, E., Kyle, S., Meuth, M...C.A., Xu, X., Bansbach, C.E., Glick , G.G., Zhao, R., Ye, F., Sirbu, B.M., Titus, L.C., Shyr, Y., and Cortez, D. (2009). Functional genomic screens

  17. Biosynthesis of acid phosphatase of baker's yeast . Characterization of a protoplast-bound fraction containing precursors of the exo-enzyme

    NARCIS (Netherlands)

    Boer, Pieter; Rijn, Herman J.M. van; Reinking, A.; Steyn-Parvé, Elizabeth P.

    1975-01-01

    1. 1.|Yest protoplasts, secreting acid phosphatase (orthophosphoric-monoester phosphohydrolase (acid optimum) EC 3.1.3.2) contain a small amount of firmly bound enzyme, even after lysis (Van Rijn, H.J.M.; Boer, P. and Steyn-Parvé, E.P. (1972) Biochim. Biophys. Acta 268, 431–441). The major part

  18. Histologically diagnosed cancers in South Africa, 1988

    African Journals Online (AJOL)

    causing familial hypercholesterolemia in a South African of Indian origin. Biochim Biophys Acta 1993; 1182: 75-82. Mricans: familial hypercholesterolemia in Indians and familial defective apolipoprotein B-IOO. PhD thesis, Universiry of Cape. Town, 1992. Histologically diagnosed cancers in South Africa, 1988. F. SITAS.

  19. The Efflux of a Fluorescent Probe Is Catalyzed by an ATP-Driven Extrusion System in Lactococcus lactis

    NARCIS (Netherlands)

    MOLENAAR, D; BOLHUIS, H; ABEE, T; POOLMAN, B; KONINGS, WN

    Many bacteria, both gram positive and negative, extrude in an energy-dependent manner the fluorescent pH indicator 2',7'-bis-(2-carboxyethyl)-5[and -6]-carboxyfluorescein (BCECF) (D. Molenaar, T. Abee, and W. N. Konings, Biochim. Biophys. Acta 1115:75-83, 1991). This efflux was studied in detail in

  20. Aggregation properties of a short peptide that mediates amyloid fibril ...

    Indian Academy of Sciences (India)

    Mandelkow E 2005 Tau aggregation is driven by a transition from random coil to beta sheet structure. Biochim. Biophys. Acta 1739 158–166 von Bergen M, Barghorn S, Li L, Marx A, Biernat J, Mandelkow. EM and Mandelkow E 2001 Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical.

  1. Performances of an ATR System via its ROC Manifold

    Science.gov (United States)

    2008-07-01

    searchers,” HP Laboratories, Palo Alto CA, Technical report, 2004. [8] B. Matthews, “Comparison of the predicted and observed secondary structure of t4 ... phage lysozyme,” Biochim. Biophys. Acta, vol. 405, pp. 442–451, 1975. [9] P. Baldi, S. Brunak, Y. Chauvin, C. A. F. Andersen, and H. Nielsen

  2. Genetics Home Reference: aspartylglucosaminuria

    Science.gov (United States)

    ... UK) ClinicalTrials.gov (1 link) ClinicalTrials.gov Scientific Articles on PubMed (1 link) PubMed OMIM (1 link) ASPARTYLGLUCOSAMINURIA Sources for This Page Aronson NN Jr. Aspartylglycosaminuria: biochemistry and molecular biology. Biochim Biophys Acta. 1999 Oct 8;1455(2- ...

  3. A functional compartmental model of the Synechocystis PCC 6803 phycobilisome

    NARCIS (Netherlands)

    van Stokkum, Ivo H. M.; Gwizdala, Michal; Tian, Lijin; Snellenburg, Joris J.; van Grondelle, Rienk; van Amerongen, Herbert; Berera, Rudi

    In the light-harvesting antenna of the Synechocystis PCC 6803 phycobilisome (PB), the core consists of three cylinders, each composed of four disks, whereas each of the six rods consists of up to three hexamers (Arteni et al., Biochim Biophys Acta 1787(4):272–279, 2009). The rods and core contain

  4. A functional compartmental model of the Synechocystis PCC 6803 phycobilisome

    NARCIS (Netherlands)

    Stokkum, van Ivo H.M.; Gwizdala, Michal; Tian, Tian; Snellenburg, Joris J.; Grondelle, van Rienk; Amerongen, van Herbert; Berera, Rudi

    2018-01-01

    In the light-harvesting antenna of the Synechocystis PCC 6803 phycobilisome (PB), the core consists of three cylinders, each composed of four disks, whereas each of the six rods consists of up to three hexamers (Arteni et al., Biochim Biophys Acta 1787(4):272–279, 2009). The rods and core contain

  5. Association of Inflammatory Cytokines with Traditional and ...

    African Journals Online (AJOL)

    potential causal component mixtures and mechanisms. Environ Health Perspect 2009;117:1232‑8. 38. Turunen MP, Aavik E, Ylä‑Herttuala S. Epigenetics and atherosclerosis. Biochim Biophys Acta 2009;1790:886‑91. 39. Yajnik CS, Deshmukh US. Fetal programming: Maternal nutrition and role of one‑carbon metabolism.

  6. Mucin (MUC1) Expression and Function in Prostate Cancer Cells

    Science.gov (United States)

    2001-09-01

    Composition in Streptococcus faecium . Biochim. Biophys. Acta, 575:225-233, Carson, Daniel D., Ph.D. 1979. 3. Carson, D., Pieringer, R.A., and Daneo-More, L...Effect of Growth Rate on Lipid and Lipoteichoic Acid Composition in Streptococcus faecium . Biochem. Biphys. Acta, 575:225- . 233,1979. 4. Daneo...Moore, L., Bourbeau, P., Weinstein R., and Carson, D. Effect of Cerulenin on Antibiotic-Induced Lysis of Streptococcus faecalis (S. faecium

  7. Eunuchs in the Bible | Retief | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  8. The word that moves | Welzen | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  9. What is spirituality? | Waaijman | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  10. Spirituality and contextuality | Waaijman | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  11. Chapter 2: Methodology | Ito | Acta Theologica

    African Journals Online (AJOL)

    Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  12. Praying Through Kenosis | Williams | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  13. Conformity in Christ | Waaijman | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your Web browser ...

  14. Hippocrates: facts and fiction | Retief | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  15. [The thirty years of Acta Genetica Sinica].

    Science.gov (United States)

    Li, Shao-Wu; Zhou, Su; Xue, Yong-Biao; Zhu, Li-Huang

    2003-04-01

    Acta Genetica Sinica (AGS) is sponsored by the Genetics Society of China and the Institute of Genetics and Developmental Biology of Chinese Academy of Sciences, and is published by Science Press. The journal is a leading national academic periodical and one of the Chinese key periodicals of natural sciences. Currently, AGS is being indexed by several well-known domestic and international indexing systems, such as the American Chemical Digest (CA), BIOSIS database, Biological Digest (BA), Medical Index and Russian Digest (P [symbol: see text]). Papers in the areas of genetics, developmental biology, cell molecular biology and evolution are regularly published by AGS.

  16. Photosynthetic Responses to the Environment. Proceedings Symposium held August 24 - 27, 1992. Volume 8

    Science.gov (United States)

    1992-08-27

    150. satellite 235, 242, 243, 246 data 246 Picea abies 193 remote sensing 247 Pisum sativum 161 seasonal changes 193 Pittosporum tobira 176 senescence...it will be difficult to predict the consequences of ozone depletion on untested species and within a changing global atmosphere and climate ...Strid A, Chow WS, Anderson JM (1990) Effects of supplementary ultraviolet-B radiation on photosynthesis in Pisum sativum . Biochim Biophys Acta 1020

  17. Structure and Function of Cobrotoxin

    Science.gov (United States)

    1976-01-01

    cobra venom Chemical studeis show that cobrotoxin is a small, basic protei consisting of a single peptide chain of 62 amino acid residue , crosslinked...restrictt-d in their movement " educing the probability of such antibody to crosslink with intigens, i.e., non-precipitating antibody "exhibit monogamous...the toxic nature of snake venom. Intern . Coneer. Biochem. 7th, Tokyo Col. VIII, 1 (1967). 14. Studies on fluorescent cobrotoxin. Biochim. Biophys. Acta

  18. Insight into Nek2A activity regulation and its pharmacological ...

    African Journals Online (AJOL)

    Ambuj Kumar

    2012-11-28

    Nov 28, 2012 ... Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and. Nek2B. Biochim Biophys Acta 2005;1744:89–92. [24] Martin-Lluesma S, Stucke VM, Nigg EA. Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science 2002;297:2267–70. [25] Chen Y ...

  19. 50th Anniversary of Acta stomatologica Croatica.

    Science.gov (United States)

    Brkić, Hrvoje

    2016-03-01

    Acta stomatologica Croatisa (ASCRO) is scientific-professional magazine whose first issue was published back in 1966. Ever since the magazine publishers were the School of Dental Medicine of the University of Zagreb and the Croatian Dental Association of the Croatian Medical Association. Over the past fifty years two hundred regular editions were pubslihed along with three additions. The magazine has been internationally indexed and it was granted the DOI number. In this way by means of CrossCheck possible plagiarisms are being checked which aims at obtaining originality of the published results. Another peculiarity of ASCRO is bilingualism throughout the whole edition, international recognizability, open source and tradition based on sound foundations.

  20. Acta Unitatis Fratrum. Ediční projekt

    Czech Academy of Sciences Publication Activity Database

    Just, Jiří

    2014-01-01

    Roč. 29, č. 2 (2014), s. 451-462 ISSN 0231-7494 Institutional support: RVO:67985963 Keywords : The Bohemian Brethren * protestant historiography * manuscript sources * regesta edition * Acta Unitatis Fratrum Subject RIV: AB - History

  1. Appendix 1: Diagrams of taxonomy of speech acts | Ito | Acta ...

    African Journals Online (AJOL)

    Abstract. Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015.

  2. Physically-based Canopy Reflectance Model Inversion of Vegetation Biophysical-Structural Information from Terra-MODIS Imagery in Boreal and Mountainous Terrain for Ecosystem, Climate and Carbon Models using the BIOPHYS-MFM Algorithm

    Science.gov (United States)

    Peddle, D. R.; Hall, F.

    2009-12-01

    The BIOPHYS algorithm provides innovative and flexible methods for the inversion of canopy reflectance models (CRM) to derive essential biophysical structural information (BSI) for quantifying vegetation state and disturbance, and for input to ecosystem, climate and carbon models. Based on spectral, angular, temporal and scene geometry inputs that can be provided or automatically derived, the BIOPHYS Multiple-Forward Mode (MFM) approach generates look-up tables (LUTs) that comprise reflectance data, structural inputs over specified or computed ranges, and the associated CRM output from forward mode runs. Image pixel and model LUT spectral values are then matched. The corresponding BSI retrieved from the LUT matches is output as the BSI results. BIOPHYS-MFM has been extensively used with agencies in Canada and the USA over the past decade (Peddle et al 2000-09; Soenen et al 2005-09; Gamon et al 2004; Cihlar et al 2003), such as CCRS, CFS, AICWR, NASA LEDAPS, BOREAS and MODIS Science Teams, and for the North American Carbon Program. The algorithm generates BSI products such as land cover, biomass, stand volume, stem density, height, crown closure, leaf area index (LAI) and branch area, crown dimension, productivity, topographic correction, structural change from harvest, forest fires and mountain pine beetle damage, and water / hydrology applications. BIOPHYS-MFM has been applied in different locations in Canada (six provinces from Newfoundland to British Columbia) and USA (NASA COVER, MODIS and LEDAPS sites) using 7 different CRM models and a variety of imagery (e.g. MODIS, Landsat, SPOT, IKONOS, airborne MSV, MMR, casi, Probe-1, AISA). In this paper we summarise the BIOPHYS-MFM algorithm and results from Terra-MODIS imagery from MODIS validation sites at Kananaskis Alberta in the Canadian Rocky Mountains, and from the Boreal Ecosystem Atmosphere Study (BOREAS) in Saskatchewan Canada. At the montane Rocky Mountain site, BIOPHYS-MFM density estimates were within

  3. Elsevier/Spectrochimica Acta atomic spectroscopy award 2015

    Science.gov (United States)

    Omenetto, Nicolo; de Loos-Vollebregt, Margaretha

    2016-12-01

    This is to announce the 2015 Elsevier/Spectrochimica Acta award, the annual award honoring the most significant article(s) published in a volume. Elsevier makes this award on behalf of Spectrochimica Acta, Part B, to encourage the publication of top articles in this journal. All papers published during one year are considered for this award and the Editorial Advisory Board and the Guest Editor(s) of the special issue(s) are responsible for the selection. The award consists of a monetary prize of 1000 together with a presentation certificate.

  4. Elsevier/Spectrochimica Acta Atomic Spectroscopy Award 2014

    Science.gov (United States)

    Omenetto, Nicolo'; de Loos, Greet

    2016-03-01

    This is to announce the 2014 Elsevier/Spectrochimica Acta Award, the annual award honoring the most significant article(s) published in a volume. Elsevier makes this award on behalf of Spectrochimica Acta, Part B, to encourage the publication of top articles in this journal. All papers published during one year are considered for this award and the Editorial Advisory Board and the Guest Editor(s) of the special issue(s) are responsible for the selection. The award consists of a monetary prize of 1000 together with a presentation certificate.

  5. A new framework for Bible translation | Wilt | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 22, No 1 (2002) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your Web browser ...

  6. The language ecology of a new Afrikaans Bible | Ponelis | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 22, No 1 (2002) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your Web browser ...

  7. Chaoskampf in the orthodox baptism ritual | Oancea | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 37, No 2 (2017) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  8. Advertising in Actas Dermosifiliográficas, 1909-1939.

    Science.gov (United States)

    Díaz-Díaz, R M

    2014-05-01

    We review advertisements published in the journal Actas Dermosifiliográficas between 1909 and 1939. Treatments for sexually transmitted diseases were advertised with particular frequency, and they offer a case in point that exemplifies the close relationship between the pharmaceutical industry and medical journals. Copyright © 2012 Elsevier España, S.L. and AEDV. All rights reserved.

  9. Snake and staff symbolism in healing | Retief | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  10. Spirituality, theology and the critical mind | de Villiers | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  11. Theft and robbery in chrysostom's time | Stander | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 29, No 2 (2009) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  12. The death of Alexander the Great | Retief | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  13. Happiness in the Psalms | McConville | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Supplementum 15 >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your Web browser ...

  14. Biblical Metaphor: The Cosmic Garden Heritage | Green | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 34, No 1 (2014) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  15. The book, deconstruction, and the religious sign | Gheitury | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 29, No 1 (2009) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  16. The “turn” to spirituality | Kourie | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your Web browser ...

  17. Towards a Spirituality of Peace | De Villiers | Acta Theologica

    African Journals Online (AJOL)

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  18. Contours of Biblical spirituality as a discipline | Welzen | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Supplementum 15 >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your ...

  19. Paupertas (poverty) in John Calvin's Institutes | Britz | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 28, No 2 (2008) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  20. Christ's crucifixion as a medico-historical event | Retief | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your Web browser ...

  1. ACTA BIOETHICA: UNA DÉCADA DE HISTORIA ACTA BIOETHICA: UMA DÉCADA DE HISTÓRIA ACTA BIOETHICA: A DECADE OF HISTORY

    Directory of Open Access Journals (Sweden)

    Fernando Lolas Stepke

    Full Text Available Se presenta una síntesis histórica del origen y evolución de Acta Bioethica (ISSN 0717-5906, destacando los temas abordados en sus primeros diez años y el origen geográfico de los artículos publicados. Indexada en SciELO, Science Citation Index, Latindex y otras bases de datos internacionales, la revista se ha convertido en referencia obligada para los estudiosos. Sus artículos, en inglés, español y portugués, se citan cada vez con mayor frecuencia. El Centro Interdisciplinario de Estudios en Bioética (CIEB de la Universidad de Chile, que la editó durante la vigencia del consorcio con el Programa de Bioética OPS/OMS, continúa incrementando su presencia en los medios especializados.Apresenta-se uma síntese histórica da origem e evolução da Acta Bioethica (ISSN 0717-5906, destacando-se os temas abordados nos seus primeiros dez anos e a origem geográfica dos artigos publicados. Indexada em SciELO, Science Citation Index, Latindex e outras bases de dados internacionais, a revista se tornou uma referência obrigatória para os estudiosos. Seus artigos em inglês, espanhol e português são citados cada vez mais e com maior frequência. O Centro Interdisciplinar de Estudos em Bioética (CIEB da Universidade do Chile, que a editou durante a vigência do consórcio com o Programa de Bioética OPS/OMS, continua incrementando a sua presença nos meios especializados.A historical account of origin and evolution of Acta Bioethica (ISSN 0717-5906 is presented, emphasizing the topics addressed and the geographical origin of its authors during its first ten years of existence. Indexed in SciELO, Science Citation Index, Latindex and other bibliographic databases, the journal has become standard reference for scholars. Its papers, in English, Spanish and Portuguese, are cited with increasingly higher frequency. The Centro Interdisciplinario de Estudios en Bioética (CIEB, at the University of Chile, which edited it during the time of the

  2. Therapeutic Role of Bmi-1 Inhibitors in Eliminating Prostate Tumor Stem Cells

    Science.gov (United States)

    2015-10-01

    inhibiting p16(INK4A) and p14(ARF) expression. 2008, Biochim Biophys Acta 1782:642-8. 11. Fasano CA, Dimos JT, Ivanova NB, Lowry N, Lemischka IR... Thomas Davis , Prof. Robert DiPaola , Prof. Joseph Bertino Abstract Current prostate cancer (PCa) management calls for identifying novel and more...Medina1,6, John Kerrigan1, Mark N. Stein1,6, Isaac Y. Kim1,7, 5 Thomas W. Davis4, Robert S. DiPaola1,6, Joseph R. Bertino1,2,6*, Hatem E. Sabaawy1,2,3,6

  3. Biochemical Characterization of P4-ATPase Mutations Associated with Intrahepatic Cholestatic Disease

    DEFF Research Database (Denmark)

    Gantzel, Rasmus; Vestergaard, Anna Lindeløv; Mikkelsen, Stine

    The cholestatic disorders progressive familial intrahepatic cholestasis type 1 (PFIC1, also referred to as Byler’s disease) and benign recurrent intrahepatic cholestasis type 1 (BRIC1) are caused by mutation of the P4-ATPase ATP8B1. The substrate of ATP8B1 is very likely to be phosphatidylserine ...... in the transmembrane domain will contribute with important information in elucidation of the phospholipid transport mechanism of P4-type ATPases. 1. Folmer, D.E., R.P.J. Oude Elferink, and C.C. Paulusma, Biochim. Biophys. Acta (2009) 1791. 628-635....

  4. Acta stomatologica Croatica and PubMed Central.

    Science.gov (United States)

    Brkić, Hrvoje

    2016-06-01

    April 15 2016 marked the 50th anniversary of continuous publishing of the journal Acta stomatologica Croatica (ASCRO). The celebration was held in the great hall of the Croatian Medical Association, with numerous guests from the biomedical field. The history of the journal was presented by Goran Knežević (editor-in-chief 1996-2006) and Hrvoje Brkić (current editor-in-chief), who presented all the current information on the electronical editing and its current indexation. Only a few days later, the Editorial Office received the information that ASCRO has been included in PubMed Central since volume 48, an impulse for the members of the Editorial Board and the Editor-in-Chief to make ASCRO better and more cited.

  5. Acta Clinica Croatica: progress of a journal step by step.

    Science.gov (United States)

    Ramljak, Gordana

    2014-03-01

    The journal Acta Clinica Croatica (ACC) was founded in 1962 under the title Anali Bolnice Dr. M. Stojanović. In 1995, the title of the journal was changed into its present form and ever since all papers have been published in English. In 2000, the electronic (online) edition of the ACC was released in addition to the print version. The paper presents development of the journal from 1962 to 2012 based on the analysis of the following SCOPUS citation index parameters: type and number of documents published in the journal; number of citations; and number of domestic and foreign authors. The studied period was analyzed in three time segments: the period from 1995 to 1999, the period from 2000 to 2006 and the period from 2007 to 2012. The same parameters were analyzed in the Web of Science/SCI-Expanded bibliographic and citation index for the 2007-2012 period. The increasing number of documents, authors (both domestic and foreign) and citations demonstrates gradual rise in the quality, visibility and impact of the journal. The fifty years of experience show that a goal, at first very distant and almost unachievable, may be reached by progressing step by step.

  6. Hydrogen-1 NMR relaxation time studies in membrane: anesthetic systems; Variacao dos tempos de relaxacao longitudinal de protons em sistemas membranares contendo anestesicos locais

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, L.M.A.; Fraceto, L.; Paula, E. de [Universidade Estadual de Campinas, SP (Brazil). Dept. de Bioquimica; Franzoni, L.; Spisni, A. [Universita degli Studi di Parma, Parma (Italy). Ist. di Chimica Biologica

    1997-12-31

    The study of local anesthetics`(LA) interaction with model phospholipid membranes is justified by the direct correlation between anesthetic`s hydrophobicity and its potency/toxicity. By the same reason, uncharged LA species seems to play a crucial role in anesthesia. Most clinically used LA are small amphiphilics with a protonated amine group (pKa around 8). Although both charged (protonated) and uncharged forms can coexist at physiological pH, it has been shown (Lee, Biochim. Biophys. Acta 514:95, 1978; Screier et al. Biochim. Biophys. Acta 769:231, 1984) that the real anesthetic pka can be down-shifted, due to differential partition into membranes, increasing the ratio of uncharged species at pH 7.4. We have measured {sup 1}H-NMR longitudinal relaxation times (T{sub 1}) for phospholipid and three local anesthetics (tetracaine, lidocaine, benzocaine), in sonicated vesicles at a 3:1 molar ratio. All the LA protons have shown smaller T{sub 1} in this system than in isotropic phases, reflecting LA immobilization caused by insertion in the membrane. T{sub 1} values for the lipid protons in the presence of LA were analyzed, in an attempt to identify specific LA:lipid contact regions. (author) 13 refs., 3 figs., 1 tabs.

  7. Application of a PEG precipitation method for solubility screening: A tool for developing high protein concentration formulations

    Science.gov (United States)

    Li, Li; Kantor, Angela; Warne, Nicholas

    2013-01-01

    Previous publications demonstrated that the extrapolated solubility by polyethylene glycol (PEG) precipitation method (Middaugh et al., J Biol Chem 1979; 254:367–370; Juckes, Biochim Biophys Acta 1971; 229:535–546; Foster et al., Biochim Biophys Acta 1973; 317:505; Mahadevan and Hall, AIChE J 1990; 36:1517–1528; Stevenson and Hageman, Pharm Res 1995; 12:1671–1676) has a strong correlation to experimentally measured solubility of proteins. Here, we explored the utility of extrapolated solubility as a method to compare multiple protein drug candidates when nonideality of a highly soluble protein prohibits accurate quantitative solubility prediction. To achieve high efficiency and reduce the amount of protein required, the method is miniaturized to microwell plate format for high-throughput screening application. In this simplified version of the method, comparative solubility of proteins can be obtained without the need of concentration measurement of the supernatant following the precipitation step in the conventional method. The monoclonal antibodies with the lowest apparent solubilities determined by this method are the most difficult to be concentrated, indicating a good correlation between the prediction and empirical observations. This study also shows that the PEG precipitation method gives results for opalescence prediction that favorably compares to experimentally determined opalescence levels at high concentration. This approach may be useful in detecting proteins with potential solubility and opalescence problems prior to the time-consuming and expensive development process of high concentration formulation. PMID:23740802

  8. Actas de las Conferencias Sanitarias Internacionales (1851-1938.

    Directory of Open Access Journals (Sweden)

    Juan B. Mateos Jiménez

    2005-01-01

    Full Text Available En este breve trabajo se pretende traer a la memoria el recuerdo de las «Conferencias Sanitarias Internacionales» que, en intervalos casi regulares, se celebraron desde 1851 hasta 1938, consistiendo en una serie de reuniones en las que participaron los más importantes sanitarios, higienistas y científicos de cada época, así como los embajadores correspondientes de los más importantes países, intentando unos acuerdos que fuesen conformes para todas las naciones y que evitasen la llegada y extensión de las enfermedades pestilenciales. Esta labor resultaba harto difícil en aquellos tiempos, dado que los participantes se encontraban divididos en dos grandes y potentes grupos: los contagionistas (partidarios de los cordones sanitarios, cuarentenas y lazaretos y los miasmáticos o anticontagionistas (que rechazaban estas medidas y defendían el pleno saneamiento: individual, ambiental y general. Los descubrimientos bacteriológicos que por entonces se fueron produciendo, facilitaron los caminos para un mejor entendimiento entre los participantes en las Conferencias. En este breve trabajo se ofrece un mínimo resumen del contenido de cada una de las mismas. Hay que destacar que estas Conferencias fueron el origen de la Organización Mundial de la Salud. Se mencionan algunas de las dificultades encontradas para conseguir las fotocopias de los textos de las 14 Actas de las Conferencias. Hasta ahora solamente existían en el mundo dos colecciones completas (originales y fotocopias una en la sede de la OMS en Ginebra y otra en la Biblioteca Nacional de Medicina en Bethesda, Md. (USA. Ahora también existen en España, en el Instituto de Salud Carlos III.

  9. Appendix 4: Structural analysis chart for John 9 | Ito | Acta Theologica

    African Journals Online (AJOL)

    Abstract. Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015.

  10. Appendix 6: Chart of irony in John 9 | Ito | Acta Theologica

    African Journals Online (AJOL)

    Abstract. Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015.

  11. Appendix 5: Diagram of speech acts used in John 9 | Ito | Acta ...

    African Journals Online (AJOL)

    Abstract. Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015.

  12. Acta informatica medica is indexed in pubmed and archived in pubmed central.

    Science.gov (United States)

    Masic, Izet

    2013-03-01

    Acta Informatica Medica journal has been accepted for archiving in PubMed Central from 2011 onward. The journal started in 1993 as the official journal of the Society for Medical Informatics of Bosnia and Herzegovina. During the last 3 years, Acta Informatica Medica has een included in almost all prestigious online databases, including PubMed, Scopus and EMBASE. The 20th volume of the journal is fully international, with papers from 18 countries.

  13. Congenital mydriasis and prune belly syndrome in a child with an ACTA2 mutation.

    Science.gov (United States)

    Brodsky, Michael C; Turan, Kadriye Erkan; Khanna, Cheryl L; Patton, Alice; Kirmani, Salman

    2014-08-01

    We report the association of congenital mydriasis with prune belly syndrome and cerebrovascular anomalies in a 9-year-old boy who was found to have an ACTA2 mutation. This case illustrates the spectrum of systemic malformations that are attributable to mutations in ACTA2 and expands the spectrum of cerebrovascular anomalies that are now known to accompany congenital mydriasis. Copyright © 2014 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

  14. ActA Promotes Listeria monocytogenes Aggregation, Intestinal Colonization and Carriage

    Science.gov (United States)

    Travier, Laetitia; Guadagnini, Stéphanie; Gouin, Edith; Dufour, Alexandre; Chenal-Francisque, Viviane; Cossart, Pascale; Olivo-Marin, Jean-Christophe; Ghigo, Jean-Marc; Disson, Olivier; Lecuit, Marc

    2013-01-01

    Listeria monocytogenes (Lm) is a ubiquitous bacterium able to survive and thrive within the environment and readily colonizes a wide range of substrates, often as a biofilm. It is also a facultative intracellular pathogen, which actively invades diverse hosts and induces listeriosis. So far, these two complementary facets of Lm biology have been studied independently. Here we demonstrate that the major Lm virulence determinant ActA, a PrfA-regulated gene product enabling actin polymerization and thereby promoting its intracellular motility and cell-to-cell spread, is critical for bacterial aggregation and biofilm formation. We show that ActA mediates Lm aggregation via direct ActA-ActA interactions and that the ActA C-terminal region, which is not involved in actin polymerization, is essential for aggregation in vitro. In mice permissive to orally-acquired listeriosis, ActA-mediated Lm aggregation is not observed in infected tissues but occurs in the gut lumen. Strikingly, ActA-dependent aggregating bacteria exhibit an increased ability to persist within the cecum and colon lumen of mice, and are shed in the feces three order of magnitude more efficiently and for twice as long than bacteria unable to aggregate. In conclusion, this study identifies a novel function for ActA and illustrates that in addition to contributing to its dissemination within the host, ActA plays a key role in Lm persistence within the host and in transmission from the host back to the environment. PMID:23382675

  15. Actas que reconocen, actas que vigilan. Las constancias de alumbramiento y el control de la partería en Chiapas

    Directory of Open Access Journals (Sweden)

    Mounia El Kotni

    2017-06-01

    Full Text Available Con base en entrevistas y observación-participante, esta investigación evidencia los impactos de la convergencia de políticas públicas de salud materna e infantil y del reglamento del Registro Civil sobre la obtención de actas de nacimiento en Chiapas. En un estado donde las parteras son importantes proveedoras de servicios de salud para muchas mujeres, se revelan las dificultades a que se enfrentan las familias que acudieron a una partera no reconocida por las instituciones oficiales de salud para tramitar el acta de nacimiento de sus hijos, y cómo los grupos de población afectados se adaptan o resisten a estas situaciones.

  16. Review of the Journal Acta Informatica Medica During Eight Year Period: 2008-2015.

    Science.gov (United States)

    Masic, Izet; Begic, Edin; Zunic, Lejla

    2016-04-01

    Acta Informatica Medica is official journal of the Academy for Medical Sciences of Bosnia and Herzegovina (from 2014 Acta Inform Med is published bimonthly). To evaluate journal "Acta Informatica Medica" in 2015 and compare findings to previous years. The study has retrospective and descriptive character, and included the period 2008-2015 (included 36 issues of journal). A total of 83 (average 13,8 articles per journal) articles were published in Acta Informatica Medica during 2015. Analyzing the type of articles, original articles are present in majority during 2015 (68,6%) (by analyzing last eight years, 310 (67,3%) were original). During 2015, 27,7% of articles were related to the applied of Health informatics in field of clinical medicine, 63,8% preclinical medicine and 8,5% to public health. Collaboration rate in 2015 was 0,84. Most often the time required for decision on acceptance of article in 2015 is between 50 and 60 days. Articles came from 16 countries. According to scimagojr.com for 2014, Acta Informatica Medica has SCImago Journal Rank 0,166, while Cites / Doc. (2 years) parameter (widely used as impact index) is 0,70. According to GoogleScholar, h5 index is 11 and h5 median is 19. We analyzed the Acta Informatica Medica by "Publish or Perish" software - H index was 14, g index was 19 and e-index was 10.39. Year after year the highest number of original articles are published. Although the period of revision of articles is acceptable, the period up to two months is certainly not long, the goal is to reduce this period. Although the magazine in mentioned field found its place, although it is indexed in numerous bases, including: PubMed, PubMed Central, SCOPUS, EMBASE, EBSCO, etc. The main goal for next year is that the magazine becomes part of the Web of Science. Imperative is further internationalization of the magazine.

  17. [Scientific production in international journals by Acta Médica Portuguesa authors].

    Science.gov (United States)

    Fernandez-Llimos, Fernando; Mendes, Ana Maria

    2010-01-01

    Local and national scientific journals have been widely criticized by some authors. Additionally, they are quite rarely indexed at international databases, which results in a reduced visibility of their articles. To analyze international scientific productions of authors publishing in Acta Medica Portuguesa during 2008. A database with all the authors publishing in Acta Medica Portuguesa in 2008 was built. In July 2009, production of all those authors from the previous five years (2003-2007) was retrieved from Science Citation Index. Journals where they published, Impact Factors of those journals, articles' references, and times cited were analyzed. The 78 articles published by Acta Medica Portuguesa in 2008 were produced by 259 different authors. Ninety four (36.3%) of those authors wrote 420 articles from 2003 to 2007 indexed at Science Citation Index. These articles were published in 249 different journals, with an average Impact Factor of 2.973 (SD = 2.92). Journal with highest Impact Factor was The Lancet (IF2008 = 28.409) with two papers published. Eighty seven of those authors received some citation to their articles, with a total amount of 5001 cites. Out of the 14035 references on those 420 articles, only 10 cited any article published in Acta Médica Portuguesa. Authors publishing in Acta Médica Portuguesa produce a good amount of international publications in journals with an acceptable Impact Factor and they receive quite a good number of citations. Conversely, these authors when publishing in international journals have an extremely low citation of articles published in Acta Médica Portuguesa.

  18. Priscilianistas: Actas del I Concilio de Toledo recopiladas por Bartolomé Carranza

    Directory of Open Access Journals (Sweden)

    Ruiz de Pablos, Francisco

    2001-06-01

    Full Text Available In the current article, the author provides some documents which demonstrate that Bartolomé Carranza, (Archbishop from Toledo was the first person who compiled the «Actas from the 1st Council of Toledo», against the theory sustained by Chadwick since 1978.

    En el presente artículo el autor aporta documentos que demuestran que Bartolomé Carranza, arzobispo de Toledo, fue el primer recopilador de las Actas del I Concilio de Toledo, en contra de la teoría sostenida por Chadwick desde 1978.

  19. “Showing respect” in bible translation | van der Spuy | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 30, No 1 (2010) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  20. Twentieth-century English Bible translations | Naudé | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 25, No 2 (2005) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  1. A rhetorical analysis of Philippians 1:1-11 | Snyman | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 24, No 2 (2004) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  2. A rhetorical analysis of Philippians 1:12-26 | Snyman | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 25, No 1 (2005) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  3. Philippians 4:10-23 from a rhetorical perspective | Snyman | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 27, No 2 (2007) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your Web browser ...

  4. The spirituality of the Letter to the Galatians | Tolmie | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Supplementum 15 >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your ...

  5. Biblical spirituality: an “other” reading (allègoria) | Waaijman | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Supplementum 15 >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if your ...

  6. “Bond of love”: The action of the spirit | Williams | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 34, No 2 (2014) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  7. Psalm 51: Take not your Holy Spirit away from me | Maré | Acta ...

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 28, No 1 (2008) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  8. Lipocarbazoles, secondary metabolites from Tsukamurella pseudospumae Acta 1857 with antioxidative activity.

    Science.gov (United States)

    Schneider, Kathrin; Nachtigall, Jonny; Hänchen, Anne; Nicholson, Graeme; Goodfellow, Michael; Süssmuth, Roderich D; Fiedler, Hans-Peter

    2009-10-01

    A family of new secondary metabolites with a carbazole moiety and an alkyl side chain was isolated from Tsukamurella pseudospumae strain Acta 1857. They were named lipocarbazoles in accordance with their chemical structures, which were determined by mass spectrometry and NMR spectroscopy. Lipocarbazoles are free radical scavengers showing antioxidative activity.

  9. Muscle magnetic resonance imaging and histopathology in ACTA1-related congenital nemaline myopathy.

    Science.gov (United States)

    Castiglioni, Claudia; Cassandrini, Denis; Fattori, Fabiana; Bellacchio, Emanuele; D'Amico, Adele; Alvarez, Karin; Gejman, Roger; Diaz, Jorge; Santorelli, Filippo M; Romero, Norma B; Bertini, Enrico; Bevilacqua, Jorge A

    2014-12-01

    Muscle biopsy is usually diagnostic in nemaline myopathy (NM), but some patients may show nonspecific findings, leading to pitfalls in diagnosis. Muscle MRI is a helpful complementary tool. We assessed the clinical, histopathological, MRI, and molecular findings in a 19-year-old patient with NM in whom 2 muscle biopsies with ultrastructural examination showed no nemaline bodies. We analyzed the degree and pattern of muscle MRI involvement of the entire body, including the tongue and pectoral muscles. Muscle MRI abnormalities in sartorius, adductor magnus, and anterior compartment muscles of the leg suggested NM. A previously unreported fatty infiltration of the tongue was found. A third biopsy after the muscle MRI showed scant nemaline bodies. A novel heterozygous de novo ACTA1 c.611C>T/p.Thr204Ile mutation was detected. We highlight the contribution of muscle imaging in addressing the genetic diagnosis of ACTA1-related NM. © 2014 Wiley Periodicals, Inc.

  10. El acta única y la unión europea: una nueva soberanía

    Directory of Open Access Journals (Sweden)

    Luis MARINHO

    2010-02-01

    Full Text Available La cuestión de la supranacionalidad y de la pérdida de soberanía es tan vieja como la idea de Europa. Todos los proyectos europeos, antes del Tratado de París, fallaron porque se quiso organizar políticamente Europa, antes de intentar el rodeo de los intereses y solidaridades económicas. La cuestión vuelve a ser prioritaria con la actualización de los Tratados producidos por el Acta Única. Es legítimo preguntarse ¿significa el Acta Única una inevitable pérdida de soberanía de los Estados?

  11. Acta Alexandrinorum: questionamento dos Alexandrinos às praticas imperiais romanas

    Directory of Open Access Journals (Sweden)

    Joana Campos Clímaco

    2009-12-01

    Full Text Available The aim of this article is to illustrate the context of criticism and questioning towards the roman power in a documentation named by its editors as Acta Alexandrinorum. Through the analyses of common themes present in the selected texts, the main idea of is to investigate the initial motivation for the writing of the texts, that were spread as a kind of literary resistance of the Alexandrians towards the Empire in the II and III centuries.

  12. R179H mutation in ACTA2 expanding the phenotype to include prune-belly sequence and skin manifestations.

    Science.gov (United States)

    Richer, J; Milewicz, D M; Gow, R; de Nanassy, J; Maharajh, G; Miller, E; Oppenheimer, L; Weiler, G; O'Connor, M

    2012-03-01

    Mutations in ACTA2 (smooth muscle cell-specific isoform of α-actin) lead to a predisposition to thoracic aortic aneurysms and other vascular diseases. More recently, the ACTA2 R179H mutation has been described in individuals with global smooth muscle dysfunction. We report a patient heterozygous for the mutation in ACTA2 R179H who presented with megacystis at 13 weeks gestational age and, at birth, with prune-belly sequence. He also had deep skin dimples and creases on his palms and soles, a finding not previously described but possibly related to ACTA2. To our knowledge, this is the first report of the R179H mutation in ACTA2 in a child with prune-belly sequence. We think the R179H mutation in ACTA2 should be included in the differential diagnosis of individuals presenting with the sequence without an identified mechanical obstruction. Furthermore, as ACTA2 R179H has been reported in patients with severe vasculomyopathy and premature death, we recommend that molecular testing for this mutation be considered in fetuses presenting with fetal megacystis with a normal karyotype, particularly if the bladder diameter is 15 mm or more, to allow expectant parents to make an informed decision. Copyright © 2012 Wiley Periodicals, Inc.

  13. [National and international impact factor of Actas Españolas de Psiquiatría].

    Science.gov (United States)

    Aleixandre Benavent, R; Valderrama Zurián, J C; Castellano Gómez, M; Simó Meléndez, R; Navarro Molina, C

    2004-01-01

    The aim of this paper is to present the bibliometric indicators of Actas Españolas de Psiquiatría that were obtained from the study "Potential impact factor of the Spanish medical journals in 2001", financed by the Spanish Ministerio de Educación, Cultura y Deporte. The citations made in Actas Españolas de Psiquiatría and its national and international impact factor and immediacy index have been obtained by the use of a methodology similar to the one used by the Institute for Scientific Information. The national indicators only take into account the citations made in 87 Spanish journals considered as sources, while those from the foreign source journals of Science Citation Index have been added to the previously cited ones. Actas Españolas de Psiquiatría has obtained a national impact factor of 0.315 and an international impact factor of 0.395, which places it as a leader in the Spanish psychiatric journals.

  14. Calumenin interacts with serum amyloid P component

    DEFF Research Database (Denmark)

    Vorum, H; Jacobsen, Christian; Honoré, Bent

    2000-01-01

    We recently reported the identification of human calumenin, a novel Ca(2+) binding, transformation-sensitive and secreted protein [Vorum et al. (1998) Biochim. Biophys. Acta 1386, 121-131; Vorum et al. (1999) Exp. Cell Res. 248, 473-481] belonging to the family of multiple EF-hand proteins...... with calumenin in the presence of Ca(2+). Amino acid sequencing identified this protein as serum amyloid P component (SAP). Furthermore, we verified and characterized the calumenin-SAP interaction by the surface plasmon resonance technique. The findings indicate that calumenin may participate...... in the immunological defense system and could be involved in the pathological process of amyloidosis that leads to formation of amyloid deposits seen in different types of tissues. Udgivelsesdato: 2000-Jan-14...

  15. Comparison of Monte Carlo simulations of cytochrome b6f with experiment using Latin hypercube sampling.

    Science.gov (United States)

    Schumaker, Mark F; Kramer, David M

    2011-09-01

    We have programmed a Monte Carlo simulation of the Q-cycle model of electron transport in cytochrome b(6)f complex, an enzyme in the photosynthetic pathway that converts sunlight into biologically useful forms of chemical energy. Results were compared with published experiments of Kramer and Crofts (Biochim. Biophys. Acta 1183:72-84, 1993). Rates for the simulation were optimized by constructing large numbers of parameter sets using Latin hypercube sampling and selecting those that gave the minimum mean square deviation from experiment. Multiple copies of the simulation program were run in parallel on a Beowulf cluster. We found that Latin hypercube sampling works well as a method for approximately optimizing very noisy objective functions of 15 or 22 variables. Further, the simplified Q-cycle model can reproduce experimental results in the presence or absence of a quinone reductase (Q(i)) site inhibitor without invoking ad hoc side-reactions. © Society for Mathematical Biology 2011

  16. The glycosyl moiety of lectin from sainfoin (Onobrychis viciifolia, Scop.).

    Science.gov (United States)

    Namen, A E; Hapner, K D

    1979-09-29

    A lectin isolated from the seeds of sainfoin (Onobrychis viciifolia, Scop. var Eski) has been shown to be a glycoprotein containing 2.6% (w/w) neutral carbohydrate and 1.6% (w/w) glucosamine (Hapner, K.D. and Robbins, J.E. (1979) Biochim. Biophys. Acta 580, 186--197) A homogeneous glycopeptide accounting for 70% of the original glycoprotein carbohydrate was isolated from pronase digests of the lectin by gel filtration chromatography. Gas-liquid chromatographic and amino acid analyses showed the glycosyl portion to contain glucosamine, mannose, xylose and fucose in molar ratio to glycopeptide of 1.8 : 1.8 : 0.7 : 0.9. The amino acid sequence was determined as H2N-Ser-Asn(glycosyl)-glu-Thr-COOH. The glycosyl moiety was attached to the peptide through N-glycosidic linkage between asparagine and glucosamine.

  17. Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4

    DEFF Research Database (Denmark)

    Mereiter, Stefan; Magalhães, Ana; Adamczyk, Barbara

    2016-01-01

    Gastric carcinoma MKN45 cells stably transfected with the full-length ST3GAL4 gene were characterised by glycomic and sialoproteomic analysis. Complementary strategies were applied to assess the glycomic alterations induced by ST3GAL4 overexpression. The N- and O-glycome data were generated in two...... parallel structural analyzes, based on PGC-ESI-MS/MS. Data on glycan structure identification and relative abundance in ST3GAL4 overexpressing cells and respective mock control are presented. The sialoproteomic analysis based on titanium-dioxide enrichment of sialopeptides with subsequent LC......-MS/MS identification was performed. This analysis identified 47 proteins with significantly increased sialylation. The data in this article is associated with the research article published in Biochim Biophys Acta "Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine...

  18. Stress induced subcellular distribution of ALG-2, RBM22 and hSlu7.

    Science.gov (United States)

    Janowicz, Aleksandra; Michalak, Marek; Krebs, Joachim

    2011-05-01

    ALG-2 is a highly conserved calcium binding protein in the cytoplasm which belongs to the family of penta-EF hand proteins. Recently, we showed that ALG-2 is interacting with RBM22, a highly conserved spliceosomal nuclear protein (Montaville et al. Biochim. Biophys. Acta 1763, 1335, 2006; Krebs, Biochim. Biophys. Acta 1793, 979, 2009). In NIH 3T3 cells expressing both proteins a significant amount of ALG-2mRFP is translocated to the nucleus due to the interaction with RBM22-EGFP. hSlu7, another spliceosomal nuclear protein, known to interact with RBM22 in yeast, has been shown to translocate to the cytoplasm under cellular stress conditions. Here we provide evidence that the 2 spliceosomal proteins differ significantly in their subcellular distributions under stress conditions, and that RBM22 enhances the cytoplasmic translocation of hSlu7 under stress, especially a stress induced by thapsigargin. On the other hand, in NIH 3T3 cells expressing RBM22-EGFP and ALG-2-mRFP, ALG-2 remains translocated into the nucleus under both stress conditions, i.e. heat shock or treatment with thapsigargin. We could further demonstrate that these stress conditions had a different influence on the splicing pattern of XBP-1, a marker for the unfolded protein response indicating that ER stress may play a role in stress-induced translocation of spliceosomal proteins. The article is part of a Special Issue entitled: 11th European Symposium on Calcium. 2010 Elsevier B.V. All rights reserved.

  19. The effects of varying the expression of a neutral cholesteryl ester hydrolase on the turnover of cholesteryl ester in rat hepatoma cells.

    Science.gov (United States)

    Zolfaghari, R; Glick, J M; Fisher, E A

    1993-06-25

    A neutral bile salt-dependent cholesteryl ester hydrolase (CEH) in rat liver has been shown to be indistinguishable from the pancreatic CEH by a number of criteria (Harrison, E. H. (1988) Biochim. Biophys. Acta 963, 28-34; Zolfaghari, R., Harrison, E. H., Ross, A. C., and Fisher, E. A. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 6913-6919; Camulli, E. D., Linke, M. J., Brockman, H. L., and Hui, D. Y. (1989) Biochim. Biophys. Acta 1005, 177-182). The rat hepatoma cell line Fu5AH, which lacks this particular CEH activity, was stably transfected with the cDNA of rat pancreatic CEH, and the effects on cholesterol and cholesteryl ester metabolism in clones with varying levels of CEH expression determined. In spite of significant amounts of intracellular enzyme protein demonstrated by Western blotting, in cell lysates there was a consistently low level of catalytic activity, and in cultured cells there was no evidence that CEH served as an effective intracellular cholesteryl ester hydrolase or synthase. In contrast, the catalytic activity of the secreted enzyme was relatively higher and there was a small, but significant, increase in the ability of high density lipoprotein (added to the medium) to promote the clearance of cholesteryl ester from cells secreting high levels of CEH. Overall, these results suggest that in the liver, intracellular CEH does not significantly affect the turnover of cholesteryl esters and warrant future studies focusing on the function of the secreted enzyme. For example, secreted CEH may modify lipoproteins and affect their interactions with cells.

  20. Over 50 years of trial in Acta Psychiatrica Scandinavica: a survey

    Directory of Open Access Journals (Sweden)

    Al Marhi Muhammad O

    2009-05-01

    Full Text Available Abstract Background Randomised controlled trials are the gold standard for evaluating mental health care interventions. We assessed the content and quality of trials published in Acta Psychiatrica Scandinavica and Supplementum since 1948. Methods All trials were identified manually, quality assessed, data extracted, and sought on Medline. Results About 8.6% of all reports in the journal were clinical trials (n = 582 with the peak frequency in the 1980s. Most originate from Europe (80% and focus on depression (~38% or schizophrenia (27%. The median sample size is 44. We found only two trials that fully met the criteria of quality reporting RCTs set by CONSORT statements (0.34% since 1996. Less than 50% of records were possible to identify by a Medline search using broad methodological terms. Conclusion Acta is a major source of health trials. The standard of reporting is similar to other journals but better adherence to CONSORT would ensure higher quality of reports and better dissemination.

  1. Vergifnis in die gebed van Daniël (Dan. 9:4-19) | O'Kennedy | Acta ...

    African Journals Online (AJOL)

    Everyone is guilty - the guilt is not placed on a certain person or king (cf. v. 7); (4) Forgiveness is meant for the "international" Israel and not limited to a specific geographical area. Keywords: Ou Testament, Gebed, Vergifnis, Daniel 9: 4-19, Old Testament, Prayer, Forgiveness Acta Theologica Vol.22(1) 2003: 135-149.

  2. Search for genetic factors in bicuspid aortic valve disease: ACTA2 mutations do not play a major role.

    Science.gov (United States)

    Tortora, Giada; Wischmeijer, Anita; Berretta, Paolo; Alfonsi, Jacopo; Di Marco, Luca; Barbieri, Andrea; Marconi, Caterina; Isidori, Federica; Rossi, Cesare; Leone, Ornella; Di Bartolomeo, Roberto; Seri, Marco; Pacini, Davide

    2017-11-01

    Mutations in ACTA2 have been reported as a cause of familiar thoracic aortic aneurysm (TAA) with associated bicuspid aortic valve (BAV) in some individuals. Our aim is to investigate the role of ACTA2 mutations in BAV associated with TAA in 20 patients. We recruited 20 patients who underwent surgery for BAV and TAA; clinical genetic evaluation and ACTA2 mutation analysis were performed on each patient, along with next-generation sequencing analysis of BAV-related genes. Available first-degree relatives were enrolled and evaluated with echocardiography and clinical genetic examination. No mutations were found in ACTA2 or in BAV-related genes in our probands nor any common clinical signs possibly related to their heart disease. One-third of probands did not have any cardiovascular risk factor. Surgery was required at a young age (mean age 47.2 years) and at relatively small ascending aortic diameters (mean size 49.7 mm). In 77 first-degree relatives, 1 new diagnosis of TAA requiring surgery was made and 8 previous BAV/TAA diagnoses (9/77 = 11.7%) were confirmed. The phenotype BAV ± TAA segregated in 25% of our families. Although based on a small cohort, our results seemed to justify the conclusion that ACTA2 did not play a significant role in the pathogenesis of BAV aortopathy. The underlying genetic factors of this condition remain elusive and both large association studies and exome or genome sequencing could represent promising tools to unravel its pathogenesis. Aortic resection of TAA at elective surgery in these patients should be recommended as well as echocardiography in their first-degree relatives. © The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  3. Gender analysis of papers published in ACTAS ESPANOLAS DE PSIQUIATRIA (1999-2006).

    Science.gov (United States)

    Alonso-Arroyo, A; González-Alcaide, G; Bolaños Pizarro, M; Castelló Cogollos, L; Valderrama-Zurián, J C; Aleixandre-Benavent, R

    2008-01-01

    The governments and organizations responsible for scientific policies try to encourage equality of gender, among their priorities that of obtaining equal participation and full integration of women in all aspects of the scientific profession. The study analyzes the scientific production of women in the areas of Psychiatry by means of the bibliometric study of the papers published in ACTAS ESPANOLAS DE PSIQUIATRIA. A total of 458 papers published from 1999- 2006 period were downloaded from the Science Citation Index-Expanded database, these including original research papers, review articles and clinical cases. A bibliometric study broken down by gender was carried out to determine the existence or inequalities between men and women regarding scientific productivity, type of document, order of author signatures, on the institutional and geographical level. The papers were published by 1,194 different authors. The gender of 977 authors was identified, 587 (60.08%) men and 390 (39.92%) women. The percentage of women authorship has risen from 29.92% in 1999 to 38.86% in 2006. A total of 42.92% of authors having one published article were women, while (those with more than nine articles) only accounted for 33%. Bibliometric studies on scientific activity provide essential information to promote gender equality. An annual increase over 1% in the number of female authors in the journal has been observed, which if it continues will lead to a parity in coming years.

  4. Intellectual Property and the Tourism Industry: From ACTA Protests towards a Restrictive Interpretation of Innovation Regulations

    Directory of Open Access Journals (Sweden)

    Speriusi-Vlad Alin

    2014-01-01

    Full Text Available In 2012 became reality James Boyle’s desire exposed in his essay from 1997 regarding a politics of intellectual property concerning the great deal of attention that must be paid to the Intellectual Property. At that time Boyle was disappointed by the lack of attention from lawyers, scholars, legal academics and the media for the Clinton administration’s proposal for copyright on the Net, a document that provided the blueprint of domestic and international regulatory efforts to expand intellectual property rights. Certainly this was not the case with ACTA where the public media forced by the private citizen’s protests tried to weight both the benefits and the costs of the new protection standards brought by the new international convention. After those moments Intellectual Property regulations are no more an esoteric and arcane field, something that is only interesting and comprehensible to the practitioners in the field, but a matter of public interests like the environment which arouse the attention of all the persons. In this way we all become aware that intellectual property radiates beyond the legal frame and interferes with several aspects of our lives, including our free time and the tourism consequently.

  5. Analysis of historical articles published in Actas Urológicas Españolas.

    Science.gov (United States)

    Pérez-Albacete, M

    On the 40th anniversary of the edition of Actas Urológicas Españolas, we assess the articles on history to determine the proportion represented, analysing the study subjects and their relevance, getting to know the authors, the main study centres and the interest that the studies offer for understanding the specialty. We extracted as many subjects of historic content from the journal as were published between January 1976 and December 2016. There were 103 historical studies representing 3% of the total number of articles, with a mean of 2.57 articles published annually, written by 127 separate urologists. As first author, there were 59 articles, and as coauthors, there were 68. The main activity came from 21 of the main university hospitals in Spain, and 43 of the articles were personal articles signed by a single individual. Their content mainly covers the facts of Spanish urology from the Renaissance to the 20th century, with special emphasis on the profile of Spanish specialists. Data on 22 of these specialists are provided in 37 articles. The evolution of diagnostic and treatment procedures, both medical and surgical, are well reflected, as are a number of diseases. Most of the studies are personal works of historical research and represent 3% of the total number of articles. As a whole, the quality is high, and the articles provide data with interesting details and useful reviews, giving them considerable value, as well as forming a precious compendium for the understanding of the history of Spanish urology. These articles are highly recommended reading. Copyright © 2017 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. Actas do 13º Encontro Português de Computação Gráfica

    OpenAIRE

    Lopes, Adriano

    2005-01-01

    Actas do 13º Encontro Português de Computação Gráfica, Vila Real, 12-14 Outubro de 2005 Este livro de actas contém as contribuições dos autores para o 13º Encontro Português de Computação Gráfica, realizado em Vila Real entre 12 e 14 de Outubro de 2005. Tal como em edições anteriores, o Encontro visou essencialmente a reunião de investigadores, docentes e profissionais da Computação Gráfica e áreas afins, permitindo a divulgação de trabalhos realizados ou em curso, bem como a troc...

  7. Book Review: Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 15)

    Science.gov (United States)

    Duerbeck, H. W.; Dick, W. R.; Hamel, J.

    2002-12-01

    The 15th volume of the Acta Historica Astronomiae is at the same time the fifth collection of essays on the history of astronomy (Beitraege zur Astronomiegeschichte, Band 5), edited by the historians of astronomy W.R. Dick (Potsdam) and J. Hamel (Berlin). Besides a few short notices and book reviews, the book contains 11 major articles, which deal with astronomical topics covering the time from the 16th to the 20th centuries. The first article, on the analysis and interpretation of historical horoscopes as a source of the history of science, is based on the inaugural lecture of its author, Guenther Oestmann. After a general introduction, which deals with the principles of horoscope making, the author discusses the horoscope of Count Heinrich Ranzau (1526-1598), the Danish governor of Schleswig-Holstein, who was a friend of Tycho Brahe. Oestmann shows that the astronomical-mathematical basis of such a horoscope can be reconstructed and interpreted. However, it is hardly possible to gain an insight in the process how the interpretation of a horoscope was done in detail. The second and third articles, by Franz Daxecker, deal with Athanasius Kircher and Christoph Scheiner, two catholic astronomers of the 17th century. Kircher's Organum Mathematicum is a calculating device that can be used in the fields of arithmetic, geometry, chronology, astronomy, astrology and others. The author provides extracts of the description of the Organum taken from a book by Caspar Schott, which deal with chronology and astronomy. A photograph of the Organum indicates that this tool consists of a set of tables glued on wooden or cardboard, but details of its contents and applications remain pretty obscure for the reader - a few elaborated examples would have been helpful. The second paper deals with the life of Christoph Scheiner SJ, the co-discoverer of sunspots (next to Galileo), after leaving Rome in 1633 - the year of the Galileo trial. Scheiner spent his later years in the Austrian and

  8. A.C.T.A. and the effects of the agreement on the on-line marketing strategies

    Directory of Open Access Journals (Sweden)

    Boitor, A.–B.

    2012-01-01

    Full Text Available This article presents the most controversial and discussed treaty over the last period and its consequences on the marketing strategies of different companies in fields such as the movie industry, the music industry and the publishing domain. The A.C.T.A. treaty was signed by over 27 countries, and brings up positive effects upon the strategies of those companies which suffer losses from piracy and counterfeiting of intellectual property rights. The paper reflects the changes that the treaty can bring especially to the online marketing strategies of the biggest movie studios and music production labels.

  9. Izvješće o publicističkoj aktivnosti časopisa Acta Stomatologica Croatica za 2017. godinu

    OpenAIRE

    Brkić, Hrvoje

    2018-01-01

    Acta Stomatologica Croatica tiskana je tijekom 2017. godine redovito četiri puta. Volumen 51 sadržavao je uobičajena četiri sveščića u tiskanoj i elektroničkoj verziji. U objavljenom volumenu tiskano je ukupno 35 članaka – 17 domaćih autora i 18 stranih. Na temelju mišljenja recenzenata i urednika odbijeno je 63 posto pristiglih radova. Zastupljenost znanstvenih radova bila je 66 posto, a omjer domaćih i stranih autora ujednačen. Svaki članak analiziran je CrossCheckom i ni u jednom nije p...

  10. Sensitive detection and separation of fluorescent derivatives using capillary electrophoresis with laser-induced fluorescence detection with 532nm Nd:YAG laser

    International Nuclear Information System (INIS)

    Vrabel, Patrik; Taborsky, Petr; Ryvolova, Marketa; Havel, Josef; Preisler, Jan

    2006-01-01

    Capillary electrophoresis with laser-induced fluorescence detection (CELIF) is a powerful tool for separation and sensitive determination of fluorescent species. Biologically active compounds, such as amino acids, peptides and proteins may exhibit native fluorescence, which is however often low and/or an expensive laser is required for excitation in UV. Therefore, labelling of the analytes with a fluorescent dye is usually necessary. In this work, a home-built CELIF instrument with diode pumped frequency-doubled continuous wave Nd:YAG excitation laser with feedback power regulation (532nm) was constructed. The suitability of this type of laser for LIF detection in a separation method was found excellent. A limit of detection (LOD) (S/N=3) of 2x10 -13 mol/l was achieved with rhodamine B, which is comparable to those obtained using similar instruments with Ar + laser [Y.F. Cheng, N.J. Dovichi, Science 242 (1988) 562, E.S. Yeung et al., J. Chromatogr. 608 (1992) 73]. LOD of a protein derivatized according to modified procedures [M.J. Little et al., Anal. Chim. Acta 339 (1997) 279, A. Chersi et al., Biochim. Biophys. Acta 1336 (1997) 83] was determined. Detection of the derivatives was found to be limited by insufficient reaction recovery at low analyte concentration, chemical noise, separation efficiency and quality of the derivatizing reagent rather than by the detector performance. As a consequence, a huge gap between the detection ability of CELIF instruments and LOD determined in real samples is revealed

  11. Twenty years of society of medical informatics of b&h and the journal acta informatica medica.

    Science.gov (United States)

    Masic, Izet

    2012-03-01

    In 2012, Health/Medical informatics profession celebrates five jubilees in Bosnia and Herzegovina: a) Thirty five years from the introduction of the first automatic manipulation of data; b) Twenty five years from establishing Society for Medical Informatics BiH; c) Twenty years from establishing scientific and professional journal of the Society for Medical Informatics of Bosnia and Herzegovina "Acta Informatica Medica"; d) Twenty years from establishing first Cathdra for Medical Informatics on biomedical faculties in Bosnia and Herzegovina and e) Ten years from the introduction of "Distance learning" in medical curriculum. All of the five mentioned activities in the area of Medical informatics had special importance and gave appropriate contribution in the development of Health/Medical informatics in Bosnia And Herzegovina.

  12. Barreras y acciones para mejorar la calidad y el impacto de Acta Pediátrica de México

    Directory of Open Access Journals (Sweden)

    Francisco Espinosa-Rosales

    2017-03-01

    Full Text Available Acta Pediátrica de México se publica desde 1980 de manera puntual e ininterrumpida; es el Órgano Oficial del Instituto Nacional de Pediatría. Es una publicación bimestral que tiene como propósito fundamental la difusión de evidencia científica y de información generada como producto de investigación original básica, clínica, epidemiológica y social en el campo de la pediatría, que permita generar y mejorar los modelos de atención a la salud durante la infancia y la adolescencia. Desde 2013, el equipo editorial de la revista se renovó y desde entonces hemos identificado barreras e implementado acciones para lograr mejorar su calidad e impacto.

  13. Evaluation of the key words used in articles of the Acta Cirurgica Brasileira from 1997 to 2012.

    Science.gov (United States)

    Teixeira, Renan Kleber Costa; Gonçalves, Thiago Barbosa; Yamaki, Vitor Nagai; Botelho, Nara Macedo; Brito, Marcus Vinicius Henriques

    2012-05-01

    To evaluate the key words used in Acta Cirurgica Brasileira from 1997 to 2012. All the key words of all articles published in regular issues between 1997 and 2012 were analyzed, ensuring that these key words were in the MeSH database (Medical Subjects Headings) and the most used subject headings and most wrong repeated key words were ranked. > 4230 key words used in 990 articles were analyzed. Only 579 key words (13.68%) were not in the MeSH database, considering that there was a statistically significant decrease over the years (p<0.001). The three most used key words were Rats, Dogs and Wound healing. Among the wrong ones, the key words were Adhesions, Experimental surgery and Anatomosis. There was a gradual improvement in the amount of key words used that belonged to the MeSH database, and there were 618 articles (62.42%) with all key words correct.

  14. Evaluation of the implant-related restorative undergraduate programme at ACTA, the Netherlands. Part I: students' satisfaction.

    Science.gov (United States)

    Fijnheer, C; Langhorst, F R; Wismeijer, D

    2016-05-01

    Due to the increasing use of dental implants, many future dentists will encounter implant-related procedures in general practice. Over the past decade, implant dentistry is more and more often included in undergraduate curricula. Very little is known about students' satisfaction regarding implant-related undergraduate programmes, as minimal analyses are performed. In particular, a lack of information exists regarding programmes where undergraduates restore implants. This study describes an evaluation of the students' satisfaction regarding the implant-related restorative undergraduate programme at ACTA, the Netherlands. After clinical examination and establishment of the treatment plan, undergraduates were required to assist postgraduate implantology students during surgery. All patients received Straumann (Basel, Switzerland) implants. The restorative phase of the treatment was subsequently performed by the undergraduates. A students' questionnaire was developed. All questions were exclusively on the restorative part of the implant-related programme. In total, 90 patients were treated by 78 undergraduates. 146 Straumann implants were restored with 121 restorations. The most common restoration was a single crown (80.2%), followed by three-unit fixed partial dentures (12.4%). The questionnaires showed a high rate of students' satisfaction concerning the restorative implant programme. Students replied they think they can manufacture an implant-supported crown or FDP without supervision after following the programme. In their opinion, the existence of the restorative programme should definitely be continued. According to positive student perceptions, an implant-related restorative programme should be recommended for implementation in undergraduate dental curricula. The programme at ACTA could be used as a template for other universities. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  15. An experimental and computational study of the effect of ActA polarity on the speed of Listeria monocytogenes actin-based motility.

    Directory of Open Access Journals (Sweden)

    Susanne M Rafelski

    2009-07-01

    Full Text Available Listeria monocytogenes is a pathogenic bacterium that moves within infected cells and spreads directly between cells by harnessing the cell's dendritic actin machinery. This motility is dependent on expression of a single bacterial surface protein, ActA, a constitutively active Arp2,3 activator, and has been widely studied as a biochemical and biophysical model system for actin-based motility. Dendritic actin network dynamics are important for cell processes including eukaryotic cell motility, cytokinesis, and endocytosis. Here we experimentally altered the degree of ActA polarity on a population of bacteria and made use of an ActA-RFP fusion to determine the relationship between ActA distribution and speed of bacterial motion. We found a positive linear relationship for both ActA intensity and polarity with speed. We explored the underlying mechanisms of this dependence with two distinctly different quantitative models: a detailed agent-based model in which each actin filament and branched network is explicitly simulated, and a three-state continuum model that describes a simplified relationship between bacterial speed and barbed-end actin populations. In silico bacterial motility required a cooperative restraining mechanism to reconstitute our observed speed-polarity relationship, suggesting that kinetic friction between actin filaments and the bacterial surface, a restraining force previously neglected in motility models, is important in determining the effect of ActA polarity on bacterial motility. The continuum model was less restrictive, requiring only a filament number-dependent restraining mechanism to reproduce our experimental observations. However, seemingly rational assumptions in the continuum model, e.g. an average propulsive force per filament, were invalidated by further analysis with the agent-based model. We found that the average contribution to motility from side-interacting filaments was actually a function of the ActA

  16. Streptomyces rochei ACTA1551, an indigenous Greek isolate studied as a potential biocontrol agent against Fusarium oxysporum f.sp. lycopersici.

    Science.gov (United States)

    Kanini, Grammatiki S; Katsifas, Efstathios A; Savvides, Alexandros L; Karagouni, Amalia D

    2013-01-01

    Many studies have shown that several Greek ecosystems inhabit very interesting bacteria with biotechnological properties. Therefore Streptomyces isolates from diverse Greek habitats were selected for their antifungal activity against the common phytopathogenic fungus Fusarium oxysporum. The isolate encoded ACTA1551, member of Streptomyces genus, could strongly suppress the fungal growth when examined in antagonistic bioassays in vitro. The isolate was found phylogenetically relative to Streptomyces rochei after analyzing its 16S rDNA sequence. The influence of different environmental conditions, such as medium composition, temperature, and pH on the expression of the antifungal activity was thoroughly examined. Streptomyces rochei ACTA1551 was able to protect tomato seeds from F. oxysporum infection in vivo while it was shown to promote the growth of tomato plants when the pathogen was absent. In an initial effort towards the elucidation of the biochemical and physiological nature of ACTA1551 antifungal activity, extracts from solid streptomycete cultures under antagonistic or/and not antagonistic conditions were concentrated and fractionated. The metabolites involved in the antagonistic action of the isolate showed to be more than one and produced independently of the presence of the pathogen. The above observations could support the application of Streptomyces rochei ACTA1551 as biocontrol agent against F. oxysporum.

  17. Streptomyces rochei ACTA1551, an Indigenous Greek Isolate Studied as a Potential Biocontrol Agent against Fusarium oxysporum f.sp. lycopersici

    Directory of Open Access Journals (Sweden)

    Grammatiki S. Kanini

    2013-01-01

    Full Text Available Many studies have shown that several Greek ecosystems inhabit very interesting bacteria with biotechnological properties. Therefore Streptomyces isolates from diverse Greek habitats were selected for their antifungal activity against the common phytopathogenic fungus Fusarium oxysporum. The isolate encoded ACTA1551, member of Streptomyces genus, could strongly suppress the fungal growth when examined in antagonistic bioassays in vitro. The isolate was found phylogenetically relative to Streptomyces rochei after analyzing its 16S rDNA sequence. The influence of different environmental conditions, such as medium composition, temperature, and pH on the expression of the antifungal activity was thoroughly examined. Streptomyces rochei ACTA1551 was able to protect tomato seeds from F. oxysporum infection in vivo while it was shown to promote the growth of tomato plants when the pathogen was absent. In an initial effort towards the elucidation of the biochemical and physiological nature of ACTA1551 antifungal activity, extracts from solid streptomycete cultures under antagonistic or/and not antagonistic conditions were concentrated and fractionated. The metabolites involved in the antagonistic action of the isolate showed to be more than one and produced independently of the presence of the pathogen. The above observations could support the application of Streptomyces rochei ACTA1551 as biocontrol agent against F. oxysporum.

  18. Coverage of Acta Dermatovenerologica Alpina, Pannonica et Adriatica in Elsevier's CiteScore index: a new tool for measuring the citation impact of academic journals.

    Science.gov (United States)

    Poljak, Mario

    2017-03-01

    In December 2016, Elsevier launched a new tool that helps measure the citation impact of academic journals, called the CiteScore index. The CiteScore index values for 2015 confirmed the status of Acta Dermatovenerologica Alpina, Pannonica et Adriatica (Acta Dermatovenerol APA) as the leading journal in dermatology and sexually transmitted infections in the region. Sixty-five articles published in Acta Dermatovenerol APA from 2012 to 2014 received a total of 77 citations in 2015, resulting in a CiteScore index value of 1.18 for the journal. More than half of the articles published from 2012 to 2014 received at least one citation in 2015. Acta Dermatovenerol APA performed well in all three categories listed because it is ranked 384th out of 1,549 journals in the category General Medicine (75th percentile), 53rd out of 122 journals in the category Dermatology (56th percentile), and 142nd out of 246 journals in the category Infectious Diseases (42nd percentile).

  19. Structural and gene expression analyses of uptake hydrogenases ...

    Indian Academy of Sciences (India)

    2013-10-01

    Oct 1, 2013 ... Bioinformatics Conference, Proceedings 728–729. Fleming AI, Wittenberg JB, Wittenberg BA, Dudman WF and. Appleby CA 1987 The purification, characterization and ligand-binding kinetics of hemoglobins from root-nodules of the non-leguminous Casuarina-Glauca-Frankia symbiosis. Biochim. Biophys.

  20. La revista Acta Universitaria: su Trayectoria a Diez años de su Publicación Inicial

    Directory of Open Access Journals (Sweden)

    Esperanza R. Vargas Pacheco

    2012-02-01

    Full Text Available In the latter part of the XIX century Don Vicente Fernández, professor of the Colegio del Estado, proposed that a journal should be edited covering scientific themes such as mathematics, physics, chemistry, zoology, botany, mineralogy and astronomy. His idea became a reality when in 1991 the Universidad de Guanajuato edited a journal,Acta Universitaria, with the characteristics that he had proposed. Ever since 17 issues have been published containing articles that come from different disciplines including sciences, social sciences, humanities, business and economics. A great number of these articles have been contributions of professors in the areas of agriculture, biology, chemistry, physics, medicine and engineering. In addition, other topics covered have been philosophy and other humanities. In the present article the evolution of the journal is examined to determine how many national and international articles have been published in the journal and the contribution of the academic units of the Universidad de Guanajuato as well. Desde fines del siglo XIX Don Vicente Fernández, profesor del Colegio del Estado propuso que se editara una publicación periódica que versara sobre temas científicos como Matemáticas, Física, Química, Zoología, Botánica, Mineralogía y Astronomía. A partir de 1991 la Universidad de Guanajuato edita una revista con tal propósito que es Acta Universitaria. De esta publicación se han editado con el presente 17 números que contienen artículos en las distintas áreas del conocimiento, incluyendo las científicas, sociales, humanísticas y económico-administrativas. De los artículos publicados la mayor parte han sido contribuciones de profesores del área de ciencias agrícolas, biología, química, física, médicas e ingenierías. Aunque también existe una aportación importante de filosofía y en general de las humanidades. Se revisa la revista y su evolución analizando cuantas y que instituciones

  1. Acta Structilia: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  2. Acta Theologica - Supplementum 17

    African Journals Online (AJOL)

    Pavel Aleksadrovič Florenskij's method of discerning spiritual truth · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. C Camilleri, 228-246. http://dx.doi.org/10.4314/actat.v32i2S.13 ...

  3. Acta Theologica: Submissions

    African Journals Online (AJOL)

    Die Kunst der Argumentation bei Paulus. Studien zur antiken Rhetorik. Tübingen: Mohr Siebeck. WUNT 1.149. SCHWÖBEL, C. (ED.) 1995. Trinitarian theology today. Essays on divine being and act. Edinburgh: T&T Clark. Please note: Comma after the surname. Full stops after the initials. If there is more than one initial, ...

  4. Archives: Acta Theologica

    African Journals Online (AJOL)

    , No 2 (2017). 2016. Vol 36, No 1 (2016) · 2016: SUPPLEMENTUM 23. 2015. Vol 35, No 2 (2015) · Vol 35, No 1 (2015) · 2015: SUPPLEMENTUM 21 · 2015: SUPPLEMENTUM 22. 2014. Vol 34, No 2 (2014) · Vol 34, No 1 ...

  5. Acta Structilia: Editorial Policies

    African Journals Online (AJOL)

    ... journal for independently adjudicated research articles on any topic in the field of the physical and development sciences on subjects in any applicable field of scholarship, i.e. architecture, urban and regional planning, quantity surveying, construction management and project management, building economy, engineering ...

  6. Acta Theologica: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  7. Acta Structilia: Submissions

    African Journals Online (AJOL)

    After that use a) etc. 11. Source references in the text must be in the Harvard style of referencing (Author, date: pages). i. e. (Schleien, 2006: 20-40). 12. Foot- and endnotes are likewise done in the Harvard style of referencing. 13. The references list (Harvard style of referencing) should contain all the relevant information, ...

  8. Acta Theologica - 2014

    African Journals Online (AJOL)

    Remembering the Heidelberg Catechism in South Africa today? Some remarks on the commemoration of a 16 century reformed confession · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. R Vosloo, 1-15. http://dx.doi.org/10.4314/actat.v20i1.1S ...

  9. Acta Cirúrgica Brasileira. Visibilidade e acessibilidade da produção científica na área da cirurgia experimental

    Directory of Open Access Journals (Sweden)

    Población Dinah Aguiar

    2001-01-01

    Full Text Available A visibilidade da ciência divulgada pela Acta Cirúrgica Brasileira é analisada ao longo da trajetória de 15 anos de publicação ininterrupta, durante a qual foi mantida a periodicidade proposta. Com isto obteve os créditos necessários, para ser selecionada por autores nacionais e estrangeiros que publicaram 116 artigos no primeiro qüinqüênio (1986-1990, 170 no segundo qüinqüênio (1991-1995 e 190 no terceiro qüinqüênio (1996-2000 e também para ser inserida na Base LILACS desde 1987. A partir de maio de 1998 foi credenciada, entre os periódicos brasileiros da área da saúde, para ser incorporada ao Projeto SciELO Brasil. Os indicadores da Base SciELO permitem avaliar a posição da ACTA quanto às características formais de publicação revelando a qualidade científica por meio dos relatórios de uso do "site", acesso aos artigos e às revistas citantes. Análises cienciométricas são realizadas para avaliar a visibilidade e acessibilidade da literatura científica publicada na ACTA.

  10. Bioaccumulation of copper ions by Escherichia coli expressing vanabin genes from the vanadium-rich ascidian Ascidia sydneiensis samea.

    Science.gov (United States)

    Ueki, Tatsuya; Sakamoto, Yasuhisa; Yamaguchi, Nobuo; Michibata, Hitoshi

    2003-11-01

    The genes encoding two vanadium-binding proteins, vanabin1 and vanabin2, from a vanadium-rich ascidian, Ascidia sydneiensis samea, were recently identified and cloned (T. Ueki, T. Adachi, S. Kawano, M. Aoshima, N. Yamaguchi, K. Kanamori, and H. Michibata, Biochim. Biophys. Acta 1626:43-50, 2003). The vanabins were found to bind vanadium(IV), and an excess of copper(II) ions inhibited the binding of vanadium(IV) to the vanabins in vitro. In this study, we constructed Escherichia coli strains that expressed vanabin1 or vanabin2 fused to maltose-binding protein (MBP) in the periplasmic space. We found that both strains accumulated about twenty times more copper(II) ions than the control BL21 strain, while no significant accumulation of vanadium was observed. The strains expressing either MBP-vanabin1 or MBP-vanabin2 absorbed approximately 70% of the copper ions in the medium to which 10 micro M copper (II) ions were initially added. The MBP-vanabin1 and MBP-vanabin2 protein expressed in the periplasm bound to copper ions at a copper:protein molar ratio of 8:1 and 5:1, respectively, but MBP did not bind to copper ions. These data showed that the metal-binding proteins vanabin1 and vanabin2 bound copper ions directly and enhanced the bioaccumulation of copper ions by E. coli.

  11. Kinetics of hydrogen peroxide elimination by astrocytes and C6 glioma cells analysis based on a mathematical model.

    Science.gov (United States)

    Makino, Nobuo; Mise, Takeshi; Sagara, Jun-Ichi

    2008-06-01

    Oxidative stress is implicated in a variety of disorders including neurodegenerative diseases, and H(2)O(2) is important in the generation of reactive oxygen and oxidative stress. In this study, we have examined the rate of extracellular H(2)O(2) elimination and relevant enzyme activities in cultured astrocytes and C6 glioma cells and have analyzed the results based on a mathematical model. As compared with other types of cultured cells, astrocytes showed higher activity of glutathione peroxidase (GPx) but lower activities for GSH recycling. C6 cells showed relatively low GPx activity, and treatment of C6 cells with dibutyryl-cAMP, which induces astrocytic differentiation, increased catalase activity and H(2)O(2) permeation rate but exerted little effect on other enzyme activities. A mathematical model [N. Makino, K. Sasaki, N. Hashida, Y. Sakakura, A metabolic model describing the H(2)O(2) elimination by mammalian cells including H(2)O(2) permeation through cytoplasmic and peroxisomal membranes: comparison with experimental data, Biochim. Biophys. Acta 1673 (2004) 149-159.], which includes relevant enzymes and H(2)O(2) permeation through membranes, was found to be fitted well to the H(2)O(2) concentration dependences of removal reaction with the permeation rate constants as variable parameters. As compared with PC12 cells as a culture model for neuron, H(2)O(2) removal activity of astrocytes was considerably higher at physiological H(2)O(2) concentrations. The details of the mathematical model are presented in Appendix.

  12. Miscibility Critical Points in Plasma Membranes

    Science.gov (United States)

    Machta, Benjamin; Veatch, Sarah; Papanikolaou, Stefanos; Sethna, James P.

    2009-03-01

    Lipid bilayers surround all cells and are home to a host of proteins and lipids that mediate interactions between the cell and its environment. Recent experimental work has shown that simple membranes composed of three lipid components show complex phase behavior at temperatures in the physiological range. For example, two liquid phases and a gel or solid phase are seen, and a second order phase transition with Ising critical behavior can be reached at a boundary of the liquid-liquid coexistence region [1]. Surprisingly, membrane vesicles isolated from living cells can be tuned with a single parameter (temperature) to criticality [1]. This suggests that cell membranes in vivo sit near miscibility critical points, and may help explain some of the paradoxes associated with putative lipid rafts proposed in other experiments. Here we report on work mapping phase diagrams for the simple membranes utilizing NMR and microscopy data. In addition, we use canonical models of phase transitions to understand the qualitative features of the membranes. Finally we explore ideas from information theory and self organized criticality to understand how and why real cells maintain a membrane near criticality. [1] Honerkamp-Smith, Veatch, and Keller, Biochim Biophys Acta. 2008 (in press)

  13. Recycling Frank: Spontaneous emergence of homochirality in noncatalytic systems

    Science.gov (United States)

    Plasson, Raphaël; Bersini, Hugues; Commeyras, Auguste

    2004-01-01

    In this work, we introduce a prebiotically relevant protometabolic pattern corresponding to an engine of deracemization by using an external energy source. The spontaneous formation of a nonracemic mixture of chiral compounds can be observed in out-of-equilibrium systems via a symmetry-breaking phenomenon. This observation is possible thanks to chirally selective autocatalytic reactions (Frank's model) [Frank, F. C. (1953) Biochim. Biophys. Acta 11, 459–463]. We show that the use of a Frank-like model in a recycled system composed of reversible chemical reactions, rather than the classical irreversible system, allows for the emergence of a synergetic autoinduction from simple reactions, without any autocatalytic or even catalytic reaction. This model is described as a theoretical framework, based on the stereoselective reactivity of preexisting chiral monomeric building blocks (polymerization, epimerization, and depolymerization) maintained out of equilibrium by a continuous energy income, via an activation reaction. It permits the self-conversion of all monomeric subunits into a single chiral configuration. Real prebiotic systems of amino acid derivatives can be described on this basis. They are shown to be able to spontaneously reach a stable nonracemic state in a few centuries. In such systems, the presence of epimerization reactions is no more destructive, but in contrast is the central driving force of the unstabilization of the racemic state. PMID:15548617

  14. Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells.

    Directory of Open Access Journals (Sweden)

    Madalina Rujoi

    2010-09-01

    Full Text Available Niemann-Pick type C (NPC disease is a genetically inherited multi-lipid storage disorder with impaired efflux of cholesterol from lysosomal storage organelles.The effect of screen-selected cholesterol lowering compounds on the major sterol pathways was studied in CT60 mutant CHO cells lacking NPC1 protein. Each of the selected chemicals decreases cholesterol in the lysosomal storage organelles of NPC1 mutant cells through one or more of the following mechanisms: increased cholesterol efflux from the cell, decreased uptake of low-density lipoproteins, and/or increased levels of cholesteryl esters. Several chemicals promote efflux of cholesterol to extracellular acceptors in both non-NPC and NPC1 mutant cells. The uptake of low-density lipoprotein-derived cholesterol is inhibited by some of the studied compounds.Results herein provide the information for prioritized further studies in identifying molecular targets of the chemicals. This approach proved successful in the identification of seven chemicals as novel inhibitors of lysosomal acid lipase (Rosenbaum et al, Biochim. Biophys. Acta. 2009, 1791:1155-1165.

  15. The small CAB-like proteins of the cyanobacterium Synechocystis sp. PCC 6803: their involvement in chlorophyll biogenesis for Photosystem II.

    Science.gov (United States)

    Hernandez-Prieto, Miguel A; Tibiletti, Tania; Abasova, Leyla; Kirilovsky, Diana; Vass, Imre; Funk, Christiane

    2011-09-01

    The five small CAB-like proteins (ScpA-E) of the cyanobacterium Synechocystis sp. PCC 6803 belong to the family of stress-induced light-harvesting-like proteins, but are constitutively expressed in a mutant deficient of Photosystem I (PSI). Using absorption, fluorescence and thermoluminescence measurements this PSI-less strain was compared with a mutant, in which all SCPs were additionally deleted. Depletion of SCPs led to structural rearrangements in Photosystem II (PSII): less photosystems were assembled; and in these, the Q(B) site was modified. Despite the lower amount of PSII, the SCP-deficient cells contained the same amount of phycobilisomes (PBS) as the control. Although the excess PBS were functionally disconnected, their fluorescence was quenched under high irradiance by the activated Orange Carotenoid Protein (OCP). Additionally the amount of OCP, but not of the iron-stress induced protein (isiA), was higher in this SCP-depleted mutant compared with the control. As previously described, the lack of SCPs affects the chlorophyll biosynthesis (Vavilin, D., Brune, D. C., Vermaas, W. (2005) Biochim Biophys Acta 1708, 91-101). We demonstrate that chlorophyll synthesis is required for efficient PSII repair and that it is partly impaired in the absence of SCPs. At the same time, the amount of chlorophyll also seems to influence the expression of ScpC and ScpD. 2011 Elsevier B.V. All rights reserved.

  16. Efficient internalization of TAT peptide in zwitterionic DOPC phospholipid membrane revealed by neutron diffraction.

    Science.gov (United States)

    Chen, Xiaochao; Liu, Shutao; Deme, Bruno; Cristiglio, Viviana; Marquardt, Drew; Weller, Richard; Rao, Pingfan; Wang, Yunqiang; Bradshaw, Jeremy

    2017-05-01

    The aim of this study is to investigate the interactions between TAT peptides and a neutral DOPC bilayer by using neutron lamellar diffraction. The distribution of TAT peptides and the perturbation of water distribution across the DOPC bilayer were revealed. When compared to our previous study on an anionic DOPC/DOPS bilayer (X. Chen et al., Biochim Biophys Acta. 2013. 1828 (8), 1982-1988), a much deeper insertion of TAT peptides was found in the hydrophobic core of DOPC bilayer at a depth of 6.0Å from the center of the bilayer, a position close to the double bond of fatty acyl chain. We conclude that the electrostatic attractions between the positively charged TAT peptides and the negatively charged headgroups of phospholipid are not essential for the direct translocation. Furthermore, the interactions of TAT peptides with the DOPC bilayer were found to vary in a concentration-dependent manner. A limited number of peptides first associate with the phosphate moieties on the lipid headgroups by using the guanidinium ions pairing. Then the energetically favorable water defect structures are adopted to maintain the arginine residues hydrated by drawing water molecules and lipid headgroups into the bilayer core. Such bilayer deformations consequently lead to the deep intercalation of TAT peptides into the bilayer core. Once a threshold concentration of TAT peptide in the bilayer is reached, a significant rearrangement of bilayer will happen and steady-state water pores will form. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. First evidence of the pore-forming properties of a keratin from skin mucus of rainbow trout (Oncorhynchus mykiss, formerly Salmo gairdneri).

    Science.gov (United States)

    Molle, Virginie; Campagna, Sylvie; Bessin, Yannick; Ebran, Nathalie; Saint, Nathalie; Molle, Gérard

    2008-04-01

    The epidermis of fish is covered with a layer of mucus, which contributes to the defence of the species against parasites, bacteria and fungi. We have previously extracted glycoproteins from various mucus samples from fish and have shown that they present pore-forming activities well correlated with strong antibacterial properties [Ebran, Julien, Orange, Saglio, Lemaitre and Molle(2000) Biochim. Biophys. Acta 1467, 271-280]. The present study focuses on the 65 kDa glycoprotein, Tr65, from the rainbow trout (Oncorhynchus mykiss, formerly Salmo gairdneri).Enzymatic digestion of Tr65 yielded a fragment pattern with strong homology with that of trout type II cytokeratin. Sequence analysis of the cDNA clone obtained by PCR confirmed this homology. We thus constructed a plasmid to overproduce the recombinant Tr65. We extracted and purified this recombinant Tr65, using it for multichannel and single-channel experiments in azolectin bilayers. Our results with recombinant Tr65 confirmed the pore-forming properties already shown with native antibacterial Tr65. These findings offer new insights into the function of keratin proteins present in various mucosal surfaces of animals and human beings.

  18. Modulation of the transducer function of Na+,K+-ATPase: new mechanism of heart remodeling.

    Science.gov (United States)

    Lopatina, Ekaterina V; Kipenko, Anna V; Pasatetskaya, Natalia A; Penniyaynen, Valentina A; Krylov, Boris V

    2016-10-01

    Endogenous digitalis-like factors were found in the mammalian and human blood. It was the starting point for the elucidation of the new non-pumping function of the Na + ,K + -ATPase. It was previously well known that Na + ,K + -ATPase is a pharmacological target receptor for cardiac glycosides (J.C. Skou. 1957. Biochim. Biophys. Acta, 23: 394-401). We have investigated the trophotropic effects of such agents as ouabain, epinephrine, norepinephrine, atenolol, and comenic acid using the organotypic tissue culture combined with the reconstruction of optical cross sections and confocal microscopy. It was shown that the growth zone of organotypic culture forms a multidimensional structure. Our results indicate that the cardiac glycoside ouabain applied in endogenous concentrations (10 -8 , 10 -10 mol/L) can modulate transducer function of Na + ,K + -ATPase and control the cell growth and proliferation. It was also shown that Src-kinase is involved in "endogenous" ouabain activated intracellular pathways as a series unit. Epinephrine (10 -9 -10 -14 mol/L) and comenic acid (10 -6 -10 -10 mol/L) were demonstrated to modulate the growth of 10- to 12-day-old chicken embryo cardiac tissue explants in a dose-dependent manner. Epinephrine and comenic acid regulate growth and proliferation of the cardiac tissue via receptor-mediated modulation Na + ,K + -ATPase as a signal transducer. The trophotropic effects of the investigated agents specifically control the heart remodeling phenomenon.

  19. Regulation of renal function and structure by the signaling Na/K-ATPase.

    Science.gov (United States)

    Xie, Jeffrey X; Li, Xin; Xie, Zijian

    2013-12-01

    The Na/K-ATPase as an essential ion pump was discovered more than 50 years ago (Skou (1989) Biochim. Biophys. Acta 1000, 439-446; Feraille and Doucet (2001) Physiol. Rev. 81, 345-418). The signaling function of Na/K-ATPase has been gradually appreciated over the last 20 years, first from the studies of regulatory effects of ouabain on cardiac cell growth. Several reviews on this topic have been written during the last few years (Schoner and Scheiner-Bobis (2007) Am. J. Physiol. Cell. Physiol. 293, C509-C536; Xie and Cai (2003) Mol. Interv. 3, 157 - 168; Bagrov et al. (2009) Pharmacol. Rev. 61, 9-38; Tian and Xie (2008) Physiology 23, 205-211; Fontana et al. (2013) FEBS J. 280, 5450-5455; Blanco and Wallace (2013) Am. J. Physiol. Renal Physiol. 305, F797-F812). This article will focus on the molecular mechanism of Na/K-ATPase-mediated signal transduction and its potential regulatory role in renal physiology and diseases. © 2013 International Union of Biochemistry and Molecular Biology.

  20. Identification of the active site serine in pancreatic cholesterol esterase by chemical modification and site-specific mutagenesis.

    Science.gov (United States)

    DiPersio, L P; Fontaine, R N; Hui, D Y

    1990-10-05

    Chemical modification and site-specific mutagenesis approaches were used in this study to identify the active site serine residue of pancreatic cholesterol esterase. In the first approach, purified porcine pancreatic cholesterol esterase was covalently modified by incubation with [3H]diisopropylfluorophosphate (DFP). The radiolabeled cholesterol esterase was digested with CNBr, and the peptides were separated by high performance liquid chromatography. A single 3H-containing peptide was obtained for sequence determination. The results revealed the binding of DFP to a serine residue within the serine esterase homologous domain of the protein. Furthermore, the DFP-labeled serine was shown to correspond to serine residue 194 of rat cholesterol esterase (Kissel, J. A., Fontaine, R. N., Turck, C. W., Brockman, H. L., and Hui, D. Y. (1989) Biochim. Biophys. Acta 1006, 227-236). The codon for serine 194 in rat cholesterol esterase cDNA was then mutagenized to ACT or GCT to yield mutagenized cholesterol esterase with either threonine or alanine, instead of serine, at position 194. Expression of the mutagenized cDNA in COS-1 cells demonstrated that substitution of serine 194 with threonine or alanine abolished enzyme activity in hydrolyzing the water-soluble substrate, p-nitrophenyl butyrate, and the lipid substrates cholesteryl [14C]oleate and [14C] lysophosphatidylcholine. These studies definitively identified serine 194 in the catalytic site of pancreatic cholesterol esterase.

  1. The Unbinding of ATP from F1-ATPase

    Science.gov (United States)

    Antes, Iris; Chandler, David; Wang, Hongyun; Oster, George

    2003-01-01

    Using molecular dynamics, we study the unbinding of ATP in F1-ATPase from its tight binding state to its weak binding state. The calculations are made feasible through use of interpolated atomic structures from Wang and Oster [Nature 1998, 396: 279–282]. These structures are applied to atoms distant from the catalytic site. The forces from these distant atoms gradually drive a large primary region through a series of sixteen equilibrated steps that trace the hinge bending conformational change in the β-subunit that drives rotation of γ-subunit. As the rotation progresses, we find a sequential weakening and breaking of the hydrogen bonds between the ATP molecule and the α- and β-subunits of the ATPase. This finding agrees with the “binding-zipper” model [Oster and Wang, Biochim. Biophys. Acta 2000, 1458: 482–510.] In this model, the progressive formation of the hydrogen bonds is the energy source driving the rotation of the γ-shaft during hydrolysis. Conversely, the corresponding sequential breaking of these bonds is driven by rotation of the shaft during ATP synthesis. Our results for the energetics during rotation suggest that the nucleotide's coordination with Mg2+ during binding and release is necessary to account for the observed high efficiency of the motor. PMID:12885621

  2. BOOK REVIEW: Astronomie von Olbers bis Schwarzschild. Nationale Entwicklungen und internationale Beziehungen im 19. Jahrhundert (Acta Historica Astronomiae Vol. 16)

    Science.gov (United States)

    Sterken, C.; Dick, W. R.; Hamel, J.

    2002-12-01

    The 14th volume of the Acta Historica Astronomiae is the Proceedings of a Colloquium International Relationships in Astronomy (in German) organised by the History of Astronomy Section of the Astronomische Gesellschaft held on September 18 in Lilienthal, Germany. The book contains 13 articles on astronomical topics covering the 19th and 20th centuries. The first paper is by Guenther Oestmann and deals with contemporary assessments of Johann Hieronymus Schroeter's (1745-1816) astronomical works and with later judgements of the scientific importance and significance of his observations as seen by astronomers and historians. This report is complemented by a second article on Schroeter's 25-ft reflector in Lilienthal near Bremen. To this end, author Felix Luehning has constructed a scale model of the telescope, and shows how the building of a model brings a deeper understanding of function and handling of this instrument. This brings us to a third paper on telescope building in Lilienthal: Hans-Joachim Leue describes the cooperation of Johann Hieronymus Schroeter and Johann Gottlieb Schrader in developing a white reflecting metal alloy for use as telescope mirror. The fourth article, by Klaus Schillinger, describes on the basis of archival documents the aquisition history of the Herschel telescopes, including telescope quality check, repair and building. Memorial sites referring to Wilhelm Olbers, Johann Hieronymus Schroeter, Friedrich Wilhelm Bessel and Carl Friedrich Gauss are described by Arno Langkavel in two walks outlined in the very last paper of this book. Peter Brosche, in the fifth paper, discusses the rediscovery of Ceres in December1801, a discovery that was the result of the combined efforts of a theoretician (Gauss) and an observer (Zach). Juergen Hamel's paper is based on previously unused archival sources and discusses the outstanding role played by H. C. Schumacher (1780-1850, editor of the Astronomische Nachrichten) in the communication between

  3. Sensitive detection and separation of fluorescent derivatives using capillary electrophoresis with laser-induced fluorescence detection with 532nm Nd:YAG laser

    Energy Technology Data Exchange (ETDEWEB)

    Vrabel, Patrik [Department of Analytical Chemistry, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno (Czech Republic); Taborsky, Petr [Department of Analytical Chemistry, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno (Czech Republic); Ryvolova, Marketa [Department of Analytical Chemistry, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno (Czech Republic); Havel, Josef [Department of Analytical Chemistry, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno (Czech Republic); Preisler, Jan [Department of Analytical Chemistry, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno (Czech Republic)]. E-mail: preisler@chemi.muni.cz

    2006-06-15

    Capillary electrophoresis with laser-induced fluorescence detection (CELIF) is a powerful tool for separation and sensitive determination of fluorescent species. Biologically active compounds, such as amino acids, peptides and proteins may exhibit native fluorescence, which is however often low and/or an expensive laser is required for excitation in UV. Therefore, labelling of the analytes with a fluorescent dye is usually necessary. In this work, a home-built CELIF instrument with diode pumped frequency-doubled continuous wave Nd:YAG excitation laser with feedback power regulation (532nm) was constructed. The suitability of this type of laser for LIF detection in a separation method was found excellent. A limit of detection (LOD) (S/N=3) of 2x10{sup -13}mol/l was achieved with rhodamine B, which is comparable to those obtained using similar instruments with Ar{sup +} laser [Y.F. Cheng, N.J. Dovichi, Science 242 (1988) 562, E.S. Yeung et al., J. Chromatogr. 608 (1992) 73]. LOD of a protein derivatized according to modified procedures [M.J. Little et al., Anal. Chim. Acta 339 (1997) 279, A. Chersi et al., Biochim. Biophys. Acta 1336 (1997) 83] was determined. Detection of the derivatives was found to be limited by insufficient reaction recovery at low analyte concentration, chemical noise, separation efficiency and quality of the derivatizing reagent rather than by the detector performance. As a consequence, a huge gap between the detection ability of CELIF instruments and LOD determined in real samples is revealed.

  4. Por un mejor uso y distribución del agua. Libro de Actas del XI Simposio Hispano-Portugués de Relaciones Hídricas en las Plantas

    OpenAIRE

    CSIC - Instituto de Recursos Naturales y Agrobiología de Sevilla (IRNAS)

    2012-01-01

    332 páginas.-- Libro de Actas del XI Simposio Hispano-Portugués de Relaciones Hídricas en las Plantas, Sevilla 17-20 Sep. (2012) celebrado en el Paraninfo de la Universidad de Sevilla y en el Pabellón de México

  5. Poor Invasion of Trophoblastic Cells but Normal Plaque Formation in Fibroblastic Cells despite actA Deletion in a Group of Listeria monocytogenes Strains Persisting in Some Food Processing Environments

    DEFF Research Database (Denmark)

    Holch, Anne; Gottlieb, Caroline Trebbien; Larsen, Marianne Halberg

    2010-01-01

    We determined mammalian cell invasion and virulence gene (inlA, inlB, and actA) sequences of Listeria monocytogenes strains belonging to a molecular subtype (RAPD 9) that often persists in Danish fish-processing plants. These strains invaded human placental trophoblasts less efficiently than other...

  6. Acta Aeronautica et Astronautica Sinica.

    Science.gov (United States)

    1981-12-29

    SPECIMENS 68 WITH SINGLE EDGE NOTCH Liu Ligeng, Chen Xianxi and Cai Qigong (Central Iron and Steel Research Institute) ON THE DESIGN OF TRANSONIC TURBINE...et al, Mechanism of Overload Effect on Fatigue Crack Propagation in Aluminum Alloy. Eng. Fract. Mech. 1978 No. 2. (13) Chen Hu, Cai Qigong et al...this paper. 67b J-INTEGRAL EXPERIMENTAL CALIBRATION OF SHEET SPECIMENS WITH SINGLE EDGE NOTCH Lui Ligeng, Chen Xianxi and Cai Qigong (Central Iron and

  7. Acta Aeronautica et Astronautica Sinica.

    Science.gov (United States)

    1982-07-28

    Experimental value 4. Theoretical value For convenience of analysis, we used L. Lees ’ method [’] and the reference enthalpy nethod (7,9] to make...Baltakis "Influence of rouchness on heat transfer and transition" NOL TR=73-231 (AD77384). [4] C.L. Jaeck "Analysis of pressure and heat transfer test

  8. Book Reviews | Laubscher | Acta Theologica

    African Journals Online (AJOL)

    Title: Worship for the whole people of God. Vital worship for the 21st century. Author: Duck, R. (Louisville, KY: Westminster John Knox Press, 2013), pp. xxii + 334. ISBN: 978‑0‑664‑23427‑0. Title: Informed by Science, involved by Christ, How science can update, enrich and empower the Christian faith. Author: K. Nürnberger.

  9. Acta Theologica Supplementum 14 2011

    African Journals Online (AJOL)

    IT Benson

    science and reason, because these are necessary rather than sufficient factors, but we distrust anything that .... often faced with this clash and charged with managing this dialectic. (McLachlin 2004:21–22) ... development of the notion of political pluralism from Aristotle through Hobbes to. Rousseau and Rawls, showing the ...

  10. Reviews | Various Authors | Acta Theologica

    African Journals Online (AJOL)

    Trouble in the Colonies Review of D.W.A. BAKER, PREACHER, POLITICIAN, PATRIOT: A LIFE OF JOHN DUNMORE LANG. Signs of the times. A review of MARK HUTCHINSON, IRON IN OUR BLOOD, A HISTORY OF THE PRESBYTERIAN CHURCH IN NSW, 1788-2001. Review of. L. WOODHEAD, AN INTRODUCTION ...

  11. Acta Theologica - Vol 29 (2009)

    African Journals Online (AJOL)

    Hide and Seek. Aspects of the dynamics of bible translation · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. C Lombaard. http://dx.doi.org/10.4314/actat.v12i1.67241 ...

  12. Presencia musical en la Catedral de La Seu d'Urgell en la segunda mitad del siglo XVIII a través de sus actas capitulares

    Directory of Open Access Journals (Sweden)

    Roig i Capdevila, Jordi

    2004-12-01

    Full Text Available This essay is the continuation, presented as the second part, of the article published last year in this same Review, With its publication we shall have covered all of the 18th century, up to the beginning of the 19th century with respect to allusions of a musical nature made during the Chapter ceremonies in the Cathedral in the Pyrenees (the hiring and the activities of its musicians, protagonists of the religious functions with musical accompaniment, etc.. As the last issue covered the years 1700-1750, we continue on from 1751 to 1810. In this way we relate the musical life of this Cathedral music chapel, thus linking up with the anterior studies carried out by Felipe Pedrell and Higinio Anglés, who covered mostly the 16th and 17th centuries, thereby enlightening those interested concerning some of the fundamental characteristics of the cultural, social and artistic evolution of La Seu d'Urgell which stamped the city with an identity of its own.

    El presente artículo supone la continuación, como segunda parte, del publicado el año anterior en esta misma revista. Se cubre con ello todo el siglo XVIII, e incluso los primeros años del siglo XIX, en lo referente a alusiones de índole musical en las actas capitulares de la catedral pirenaica (contrataciones y actividad de sus músicos protagonistas, funciones religiosas con participación musical, etc., pues, editados en el número anterior los años 1700-1750, se prosigue ahora con los años 1751-1810. De este modo, se da noticia sobre la vida musical de esta capilla musical catedralicia, empalmando con los anteriores trabajos realizados por Felipe Pedrell e Higinio Anglés (que cubrían básicamente los siglos XVI y XVII, aproximando con ello al interesado algunas de las características fundamentales en la evolución cultural, social y artística de La Seu d'Urgell, que proporcionaron personalidad propia a la ciudad.

  13. Cyclic electron flow around PSI monitored by afterglow luminescence in leaves of maize inbred lines (Zea mays L.): correlation with chilling tolerance.

    Science.gov (United States)

    Ducruet, Jean-Marc; Roman, Miruna; Havaux, Michel; Janda, Tibor; Gallais, André

    2005-06-01

    Maize (Zea mays L.) inbred lines of contrasting chilling sensitivity (three tolerant, three sensitive lines) were acclimated to 280 mumol photons m(-2) s(-1) white light at a 17 degrees C sub-optimal temperature. They showed no symptoms of photoinhibition, despite slight changes in photosystem II (PSII) fluorescence and thermoluminescence properties in two tolerant lines. A luminescence "afterglow" emission [Bertsch and Azzi (1965) Biochim Biophys Acta 94:15-26], inducible by a far-red (FR) illumination of unfrozen leaf discs, was detected either as a bounce in decay kinetics at constant temperatures or as a sharp thermoluminescence afterglow band at about 45 degrees C, in dark-adapted leaves. This band reflects the induction by warming of an electron pathway from stromal reductants to plastoquinones and to the Q(B) secondary acceptor of PSII, resulting in a luminescence-emitting charge recombination in the fraction of centres that were initially in the S(2/3)Q(B) non-luminescent state. A 5-h exposure of plants to growth chamber light shifted this luminescence emission towards shorter times and lower temperatures for several hours in the three chilling-tolerant lines. This downshift was not observed, or only transiently, in the three sensitive lines. In darkness, the downshifted afterglow band relaxed within hours to resume its dark-adapted location, similar for all maize lines. A faster dark re-reduction of P700(+) oxidized by FR light (monitored by 820-nm absorbance) and an increase of photochemical energy storage under FR excitation (determined by photoacoustic spectroscopy) confirmed that a cyclic pathway induced by white actinic light remained activated for several hours in the tolerant maize lines.

  14. The relationship between maximum tolerated light intensity and photoprotective energy dissipation in the photosynthetic antenna: chloroplast gains and losses.

    Science.gov (United States)

    Ruban, Alexander V; Belgio, Erica

    2014-04-19

    The principle of quantifying the efficiency of protection of photosystem II (PSII) reaction centres against photoinhibition by non-photochemical energy dissipation (NPQ) has been recently introduced by Ruban & Murchie (2012 Biochim. Biophys. Acta 1817, 977-982 (doi:10.1016/j.bbabio.2012.03.026)). This is based upon the assessment of two key parameters: (i) the relationship between the PSII yield and NPQ, and (ii) the fraction of intact PSII reaction centres in the dark after illumination. In this paper, we have quantified the relationship between the amplitude of NPQ and the light intensity at which all PSII reaction centres remain intact for plants with different levels of PsbS protein, known to play a key role in the process. It was found that the same, nearly linear, relationship exists between the levels of the protective NPQ component (pNPQ) and the tolerated light intensity in all types of studied plants. This approach allowed for the quantification of the maximum tolerated light intensity, the light intensity at which all plant leaves become photoinhibited, the fraction of (most likely) unnecessary or 'wasteful' NPQ, and the fraction of photoinhibited PSII reaction centres under conditions of prolonged illumination by full sunlight. It was concluded that the governing factors in the photoprotection of PSII are the level and rate of protective pNPQ formation, which are often in discord with the amplitude of the conventional measure of photoprotection, the quickly reversible NPQ component, qE. Hence, we recommend pNPQ as a more informative and less ambiguous parameter than qE, as it reflects the effectiveness and limitations of the major photoprotective process of the photosynthetic membrane.

  15. Evolutionary, kinetic and thermodynamic aspects on the bioenergetics of inorganic pyrophosphate (PPi) and adenosine triphosphate (ATP)

    International Nuclear Information System (INIS)

    Baltscheffsky, H.; Baltscheffsky, M.

    1995-01-01

    Energy barriers for energy carriers are of fundamental significance for the successful operation of the bioenergetic reactions in living cells. PPi and ATP are outstanding ''energy-rich'' examples of molecular ''energy currencies'' in biological systems, with kinetic barriers preventing excessively fast thermodynamically feasible hydrolysis from occurring. The barriers may be considered to facilitate the energy coupling roles of these phosphate compounds, which are to secure growth and maintain numerous other energy requiring functions. The enzymes involved in overcoming the energies of activation of the bioenergetic reactions have evolved to be very well tuned for their roles. Three aspects will be discussed in some detail. The first is the fact that ATP at neutral pH is considerably more energy-rich than PPi, which thus has been called a ''poor man's ATP''. This is exemplified by the kinetic and thermodynamic differences observed between the requirements for the photosynthetic formation of PPi and ATP in certain photobacterial chromatophores by varying levels of energy supply. At lower pH, PPi and ATP are equally energy-rich, which may be of significance for acidophiles. The second concerns the possible evolutionary significance of the finding that, in the dark, a pH gradient suffices to drive extensive PPi synthesis, whereas ATP synthesis requires both a pH gradient and a membrane potential (Strid et al, Biochim. Biophys. Acta 892 (1987) 236-244). Thirdly, PPi as the most plausible predecessor to ATP in the origin and early evolution of life, will be discussed. (author). Abstract only

  16. Lipid-protein interactions in plasma membranes of fiber cells isolated from the human eye lens.

    Science.gov (United States)

    Raguz, Marija; Mainali, Laxman; O'Brien, William J; Subczynski, Witold K

    2014-03-01

    The protein content in human lens membranes is extremely high, increases with age, and is higher in the nucleus as compared with the cortex, which should strongly affect the organization and properties of the lipid bilayer portion of intact membranes. To assess these effects, the intact cortical and nuclear fiber cell plasma membranes isolated from human lenses from 41- to 60-year-old donors were studied using electron paramagnetic resonance spin-labeling methods. Results were compared with those obtained for lens lipid membranes prepared from total lipid extracts from human eyes of the same age group [Mainali, L., Raguz, M., O'Brien, W. J., and Subczynski, W. K. (2013) Biochim. Biophys. Acta]. Differences were considered to be mainly due to the effect of membrane proteins. The lipid-bilayer portions of intact membranes were significantly less fluid than lipid bilayers of lens lipid membranes, prepared without proteins. The intact membranes were found to contain three distinct lipid environments termed the bulk lipid domain, boundary lipid domain, and trapped lipid domain. However, the cholesterol bilayer domain, which was detected in cortical and nuclear lens lipid membranes, was not detected in intact membranes. The relative amounts of bulk and trapped lipids were evaluated. The amount of lipids in domains uniquely formed due to the presence of membrane proteins was greater in nuclear membranes than in cortical membranes. Thus, it is evident that the rigidity of nuclear membranes is greater than that of cortical membranes. Also the permeability coefficients for oxygen measured in domains of nuclear membranes were significantly lower than appropriate coefficients measured in cortical membranes. Relationships between the organization of lipids into lipid domains in fiber cells plasma membranes and the organization of membrane proteins are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Data set for mass spectrometric analysis of recombinant human serum albumin from various expression systems

    Directory of Open Access Journals (Sweden)

    Daryl G.S. Smith

    2015-09-01

    Full Text Available Human serum albumin (HSA is a versatile and important protein for the pharmaceutical industry (Fanali et al., Mol. Aspects Med. 33(3 (2012 209–290. Due to the potential transmission of pathogens from plasma sourced albumin, numerous expression systems have been developed to produce recombinant HSA (rHSA (Chen et al., Biochim. Biophys. Acta (BBA—Gen. Subj. 1830(12 (2013 5515–5525; Kobayashi, Biologicals 34(1 (2006 55–59. Based on our previous study showing increased glycation of rHSA expressed in Asian rice (Frahm et al., J. Phys. Chem. B 116(15 (2012 4661–4670, both supplier-to-supplier and lot-to-lot variability of rHSAs from a number of expression systems were evaluated using reversed phase liquid chromatography linked with MS and MS/MS analyses. The data are associated with the research article ‘Determination of Supplier-to-Supplier and Lot-to-Lot Variability in Glycation of Recombinant Human Serum Albumin Expressed in Oryza sativa’ where further analysis of rHSA samples with additional biophysical methods can be found (Frahm et al., PLoS ONE 10(9 (2014 e109893. We determined that all rHSA samples expressed in rice showed elevated levels of arginine and lysine hexose glycation compared to rHSA expressed in yeast, suggesting that the extensive glycation of the recombinant proteins is a by-product of either the expression system or purification process and not a random occurrence.

  18. Partial molar volumes of some 1-alkanols in erythrocyte ghosts and lipid bilayers.

    Science.gov (United States)

    Kita, Y; Miller, K W

    1982-06-08

    The partial molar volumes of 1-heptanol and 1-octanol in red cell ghosts, in egg phosphatidylcholine bilayers, and in water and phosphate buffer have been measured to a precision of better than 4% by using a density meter. In every case, the partial molar volume was independent of concentration in the range studied. In both membranes, the partial molar volume of each alcohol was close to its molar volume whereas in aqueous solution it was considerably less. Comparison of the two membranes suggests that the major contribution to the partial molar volume arises from alcohol-lipid interactions of each case. Further comparison with partial molar volumes in bulk solvents suggests that on average the alcohols retain a hydrogen bond in the lipid bilayer. The magnitude of the volume change in ghosts is some 5 times less than the corresponding area changes previously reported by others [Roth, S. H., & Seeman, P. (1972) Biochim. Biophys. Acta 255, 190-198]. These two observations can only be resolved by assuming either that the bilayer expands anisotropically, experiencing a decrease in thickness with increasing volume, or that conformational changes in membrane-associated proteins can occur at constant volume to increase membrane area. Finally, these data are used to test the critical volume hypothesis of general anesthetic action. A volume change of 0.15% in red cell ghost membranes is found to be associated with anesthesia, which compares with a value of 0.2% predicted previously from pressure reversal of anesthesia studies. In egg phosphatidylcholine bilayers, a volume change of 0.36% is associated with anesthesia. The larger change in the lipid bilayer compared to the biomembrane originates solely in their different membrane/buffer partition coefficients.

  19. Biosynthesis of a linoleic acid allylic epoxide: mechanistic comparison with its chemical synthesis and leukotriene A biosynthesiss⃞

    Science.gov (United States)

    Niisuke, Katrin; Boeglin, William E.; Murray, John J.; Schneider, Claus; Brash, Alan R.

    2009-01-01

    Biosynthesis of the leukotriene A (LTA) class of epoxide is a lipoxygenase-catalyzed transformation requiring a fatty acid hydroperoxide substrate containing at least three double bonds. Here, we report on biosynthesis of a dienoic analog of LTA epoxides via a different enzymatic mechanism. Beginning with homolytic cleavage of the hydroperoxide moiety, a catalase/peroxidase-related hemoprotein from Anabaena PCC 7120, which occurs in a fusion protein with a linoleic acid 9R-lipoxygenase, dehydrates 9R-hydroperoxylinoleate to a highly unstable epoxide. Using methods we developed for isolating extremely labile compounds, we prepared and purified the epoxide and characterized its structure as 9R,10R-epoxy-octadeca-11E,13E-dienoate. This epoxide hydrolyzes to stable 9,14-diols that were reported before in linoleate autoxidation (Hamberg, M. 1983. Autoxidation of linoleic acid: Isolation and structure of four dihydroxy octadecadienoic acids. Biochim. Biophys. Acta 752: 353–356) and in incubations with the Anabaena enzyme (Lang, I., C. Göbel, A. Porzel, I. Heilmann, and I. Feussner. 2008. A lipoxygenase with linoleate diol synthase activity from Nostoc sp. PCC 7120. Biochem. J. 410: 347–357). We also prepared an equivalent epoxide from 13S-hydroperoxylinoleate using a “biomimetic” chemical method originally described for LTA4 synthesis and showed that like LTA4, the C18.2 epoxide conjugates readily with glutathione, a potential metabolic fate in vivo. We compare and contrast the mechanisms of LTA-type allylic epoxide synthesis by lipoxygenase, catalase/peroxidase, and chemical transformations. These findings provide new insights into the reactions of linoleic acid hydroperoxides and extend the known range of catalytic activities of catalase-related hemoproteins. PMID:19244216

  20. Nitroreductase reactions of Arabidopsis thaliana thioredoxin reductase.

    Science.gov (United States)

    Miskiniene, V; Sarlauskas, J; Jacquot, J P; Cenas, N

    1998-09-07

    Arabidopsis thaliana NADPH:thioredoxin reductase (TR, EC 1.6.4.5) catalyzed redox cycling of aromatic nitrocompounds, including the explosives 2,4,6-trinitrotoluene and tetryl, and the herbicide 3,5-dinitro-o-cresol. The yield of nitro anion radicals was equal to 70-90%. Redox cycling of tetryl was accompanied by formation of N-methylpicramide. Bimolecular rate constants of nitroaromatic reduction (kcat/Km) and reaction catalytic constants (kcat) increased upon an increase in oxidant single-electron reduction potential (E(1)7). Using compounds with an unknown E(1)7 value, the reactivity of TR increased parallelly to the increase in reactivity of ferredoxin:NADP+ reductase of Anabaena PCC 7119 (EC 1.18.1.2). This indicated that the main factor determining reactivity of nitroaromatics towards TR was their energetics of single-electron reduction. Incubation of reduced TR in the presence of tetryl or 2,4-dinitrochlorobenzene resulted in a loss of thioredoxin reductase activity, most probably due to modification of reduced catalytic disulfide, whereas nitroreductase reaction rates were unchanged. This means that on the analogy of quinone reduction by TR (D. Bironaite, Z. Anusevicius, J.-P. Jacquot, N. Cenas, Biochim. Biophys. Acta 1383 (1998) 82-92), FAD and not catalytic disulfide of TR was responsible for the reduction of nitroaromatics. Tetryl, 2,4,6-trinitrotoluene and thioredoxin increased the FAD fluorescence intensity of TR. This finding suggests that nitroaromatics may bind close to the thioredoxin-binding site at the catalytic disulfide domain of TR, and induce a conformational change of enzymes (S.B. Mulrooney, C.H. Williams Jr., Protein Sci. 6 (1997) 2188-2195). Our data indicate that certain nitroaromatic herbicides, explosives and other classes of xenobiotics may interfere with the reduction of thioredoxin by plant TR, and confer prooxidant properties to this antioxidant enzyme.

  1. Effects of tumor-promoting phorbol diesters on neoplastic progression of Syrian hamster embryo cells.

    Science.gov (United States)

    O'Brien, T G; Saladik, D; Diamond, L

    1982-04-01

    The progression of normal Syrian hamster embryo cells to a neoplastic phenotype after treatment with a chemical carcinogen and continuous exposure to phorbol ester tumor promoters was studied in cell culture. Tumor promoters were able to rescue cell lines derived from individual carcinogen-treated colonies from a program of cellular senescence. In general, these cell lines did not grow in soft-agar medium or produce tumors in newborn hamsters at early passages but acquired these properties at later passages. These cell lines were used to study the temporal acquisition of a phenotypic characteristic of neoplastic rather than normal hamster embryo cells: the synergistic induction of the enzyme ornithine decarboxylase (ODC) by tumor promoter and serum growth factors (O'Brien, T. G., Saladik, D., and Diamond, L. Regulation of polyamine biosynthesis in normal and transformed hamster cells in culture. Biochim. Biophys. Acta, 632: 270, 1980). All cell lines that acquired neoplastic status with passage in culture exhibited the synergistic induction of ODC prior to their acquisition of the ability to either grow in soft-agar medium or produce tumors in newborn hamsters. Cell lines that responded to promoters with the synergistic induction of ODC accumulated greater levels of polyamines, especially putrescine, after promoter treatment than did normal cells. Tumor promoters did not affect the percentage of cells labeled with [3H]thymidine in preneoplastic cell lines, a finding similar to previous results in normal and neoplastic hamster cells. These studies demonstrate that tumor promoters can affect the early stages of neoplastic progression in carcinogen-treated Syrian hamster embryo cells and that a particular phenotypic property found in neoplastic hamster cells, the synergistic induction of ODC by tumor promoters and serum growth factors, is acquired by cell lines before they acquire neoplastic potential.

  2. Freely turning over palmitate in erythrocyte membrane proteins is not responsible for the anchoring of lipid rafts to the spectrin skeleton: a study with bio-orthogonal chemical probes.

    Science.gov (United States)

    Ciana, Annarita; Achilli, Cesare; Hannoush, Rami N; Risso, Angela; Balduini, Cesare; Minetti, Giampaolo

    2013-03-01

    Erythrocyte lipid rafts are anchored to the underlying spectrin membrane skeleton [A. Ciana, C. Achilli, C. Balduini, G. Minetti, On the association of lipid rafts to the spectrin skeleton in human erythrocytes, Biochim. Biophys. Acta 1808 (2011) 183-190]. The nature of this linkage and the molecules involved are poorly understood. The interaction is sensitive to the increase in pH and ionic strength induced by carbonate. Given the role of palmitoylation in modulating the partitioning of certain proteins between various sub-cellular compartments and the plasma membrane, we asked whether palmitoylation of p55, a peripheral protein located at the junctional complex between spectrin-actin-protein 4.1 that anchors the membrane skeleton to the lipid bilayer via the transmembrane protein glycophorin C, could contribute to the anchoring of lipid rafts to the membrane skeleton. We adopted a new, non-radioactive method for studying protein palmitoylation, based on bio-orthogonal chemical analogues of fatty acids, containing an omega-alkynyl group, to metabolically label cell proteins, which are then revealed by a "click chemistry" reaction of the alkynyl moiety with an azide-containing reporter tag. We show that the membrane localization and palmitoylation levels of p55 did not change after carbonate treatment. 2-bromopalmitate and cerulenin, two known palmitoylation inhibitors, completely inhibited p55 palmitoylation, and protein palmitoyl thioesterase-1 (PPT1) reduced it, without affecting the association between lipid rafts and membrane-skeleton, indicating, on the one hand, that p55 palmitoylation is enzymatic, and, on the other, that it is not involved in the modulation of the linkage of lipid rafts to the membrane-skeleton. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. Heat stress-induced effects of photosystem I: an overview of structural and functional responses.

    Science.gov (United States)

    Ivanov, Alexander G; Velitchkova, Maya Y; Allakhverdiev, Suleyman I; Huner, Norman P A

    2017-09-01

    Temperature is one of the main factors controlling the formation, development, and functional performance of the photosynthetic apparatus in all photoautotrophs (green plants, algae, and cyanobacteria) on Earth. The projected climate change scenarios predict increases in air temperature across Earth's biomes ranging from moderate (3-4 °C) to extreme (6-8 °C) by the year 2100 (IPCC in Climate change 2007: The physical science basis: summery for policymakers, IPCC WG1 Fourth Assessment Report 2007; Climate change 2014: Mitigation of Climate Change, IPCC WG3 Fifth Assessment Report 2014). In some areas, especially of the Northern hemisphere, even more extreme warm seasonal temperatures may occur, which possibly will cause significant negative effects on the development, growth, and yield of important agricultural crops. It is well documented that high temperatures can cause direct damages of the photosynthetic apparatus and photosystem II (PSII) is generally considered to be the primary target of heat-induced inactivation of photosynthesis. However, since photosystem I (PSI) is considered to determine the global amount of enthalpy in living systems (Nelson in Biochim Biophys Acta 1807:856-863, 2011; Photosynth Res 116:145-151, 2013), the effects of elevated temperatures on PSI might be of vital importance for regulating the photosynthetic response of all photoautotrophs in the changing environment. In this review, we summarize the experimental data that demonstrate the critical impact of heat-induced alterations on the structure, composition, and functional performance of PSI and their significant implications on photosynthesis under future climate change scenarios.

  4. Temperature dependent heterogeneous rotational correlation in lipids.

    Science.gov (United States)

    Dadashvand, Neda; Othon, Christina M

    2016-11-15

    Lipid structures exhibit complex and highly dynamic lateral structure; and changes in lipid density and fluidity are believed to play an essential role in membrane targeting and function. The dynamic structure of liquids on the molecular scale can exhibit complex transient density fluctuations. Here the lateral heterogeneity of lipid dynamics is explored in free standing lipid monolayers. As the temperature is lowered the probes exhibit increasingly broad and heterogeneous rotational correlation. This increase in heterogeneity appears to exhibit a critical onset, similar to those observed for glass forming fluids. We explore heterogeneous relaxation in in a single constituent lipid monolayer of 1, 2-dimyristoyl-sn-glycero-3-phosphocholine  by measuring the rotational diffusion of a fluorescent probe (1-palmitoyl-2-[1]-sn-glycero-3-phosphocholine), which is embedded in the lipid monolayer at low labeling density. Dynamic distributions are measured using wide-field time-resolved fluorescence anisotropy. The observed relaxation exhibits a narrow, liquid-like distribution at high temperatures (τ ∼ 2.4 ns), consistent with previous experimental measures (Dadashvand et al 2014 Struct. Dyn. 1 054701, Loura and Ramalho 2007 Biochim. Biophys. Acta 1768 467-478). However, as the temperature is quenched, the distribution broadens, and we observe the appearance of a long relaxation population (τ ∼ 16.5 ns). This supports the heterogeneity observed for lipids at high packing densities, and demonstrates that the nanoscale diffusion and reorganization in lipid structures can be significantly complex, even in the simplest amorphous architectures. Dynamical heterogeneity of this form can have a significant impact on the organization, permeability and energetics of lipid membrane structures.

  5. Ammonia differentially suppresses the cAMP chemotaxis of anterior ...

    Indian Academy of Sciences (India)

    Unknown

    first defined by Sternfeld and David (1981, 1982), are a population of cells, localized in the prespore region of the slug, that resemble anterior cells (prestalk or pst ...... tion of endogenous amino acids and proteins; Biochim. Bio- phys. Acta 43 62–66. Yamamoto A and Takeuchi I 1983 Vital staining of autophagic vacuoles in ...

  6. Combined MRI and ³¹P-MRS investigations of the ACTA1(H40Y mouse model of nemaline myopathy show impaired muscle function and altered energy metabolism.

    Directory of Open Access Journals (Sweden)

    Charlotte Gineste

    Full Text Available Nemaline myopathy (NM is the most common disease entity among non-dystrophic skeletal muscle congenital diseases. Mutations in the skeletal muscle α-actin gene (ACTA1 account for ∼25% of all NM cases and are the most frequent cause of severe forms of NM. So far, the mechanisms underlying muscle weakness in NM patients remain unclear. Additionally, recent Magnetic Resonance Imaging (MRI studies reported a progressive fatty infiltration of skeletal muscle with a specific muscle involvement in patients with ACTA1 mutations. We investigated strictly noninvasively the gastrocnemius muscle function of a mouse model carrying a mutation in the ACTA1 gene (H40Y. Skeletal muscle anatomy (hindlimb muscles and fat volumes and energy metabolism were studied using MRI and (31Phosphorus magnetic resonance spectroscopy. Skeletal muscle contractile performance was investigated while applying a force-frequency protocol (from 1-150 Hz and a fatigue protocol (80 stimuli at 40 Hz. H40Y mice showed a reduction of both absolute (-40% and specific (-25% maximal force production as compared to controls. Interestingly, muscle weakness was associated with an improved resistance to fatigue (+40% and an increased energy cost. On the contrary, the force frequency relationship was not modified in H40Y mice and the extent of fatty infiltration was minor and not different from the WT group. We concluded that the H40Y mouse model does not reproduce human MRI findings but shows a severe muscle weakness which might be related to an alteration of intrinsic muscular properties. The increased energy cost in H40Y mice might be related to either an impaired mitochondrial function or an alteration at the cross-bridges level. Overall, we provided a unique set of anatomic, metabolic and functional biomarkers that might be relevant for monitoring the progression of NM disease but also for assessing the efficacy of potential therapeutic interventions at a preclinical level.

  7. The unrelated surface proteins ActA of Listeria monocytogenes and IcsA of Shigella flexneri are sufficient to confer actin-based motility on Listeria innocua and Escherichia coli respectively.

    Science.gov (United States)

    Kocks, C; Marchand, J B; Gouin, E; d'Hauteville, H; Sansonetti, P J; Carlier, M F; Cossart, P

    1995-11-01

    Listeria monocytogenes and Shigella flexneri are two unrelated facultative intracellular pathogens which spread from cell to cell by using a similar mode of intracellular movement based on continuous actin assembly at one pole of the bacterium. This process requires the asymmetrical expression of the ActA surface protein in L. monocytogenes and the IcsA (VirG) surface protein in S. flexneri. ActA and IcsA share no sequence homology. To assess the role of the two proteins in the generation of actin-based movement, we expressed them in the genetic context of two non-actin polymerizing, non-pathogenic bacterial species, Listeria innocua and Escherichia coli. In the absence of any additional bacterial pathogenicity determinants, both proteins induced actin assembly and propulsion of the bacteria in cytoplasmic extracts from Xenopus eggs, as visualized by the formation of characteristic actin comet tails. E. coli expressing IcsA moved about two times faster than Listeria and displayed longer actin tails. However, actin dynamics (actin filament distribution and filament half-lives) were similar in IcsA- and ActA-induced actin tails suggesting that by using unrelated surface molecules, L. monocytogenes and S. flexneri move intracellularly by interacting with the same host cytoskeleton components or by interfering with the same host cell signal transduction pathway.

  8. Praying Through Kenosis | Williams | Acta Theologica

    African Journals Online (AJOL)

    ... means that prayer is a reality as it really affects God, and changes the future, and, on the other hand, retains the traditional view of God as totally sovereign, which includes his omniscience. Then, if God's approach to people is kenotic, the response of people to God, especially in prayer, should likewise be in the humility of

  9. Acta Theologica - Vol 33, No 1 (2013)

    African Journals Online (AJOL)

    A Practical-Theological perspective on corruption: towards a solution-based approach in practice · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. W Coetzer, LE Snell, 29-53. http://dx.doi.org/10.4314/actat.v33i1.2 ...

  10. Mystical Perspectives in Interreligious Dialogue | Waaijman | Acta ...

    African Journals Online (AJOL)

    The article reflects, first of all, on Paul's reaction to the questions and challenges of the Epicurean and Stoic philosophers in his audience that relates to this distinction. A second part will investigate the mystical unity of the unknowable God and his body language in Christ. In a third part some mystical perspectives on this ...

  11. The word that moves | Welzen | Acta Theologica

    African Journals Online (AJOL)

    This essay investigates the role of the Bible in spirituality by looking at the relationship between academic exegesis and spiritual reading, mysticism and language, Bible reading as an event in the relationship between God and human beings and liturgy as a mystagogical process.

  12. Eunuchs in the Bible | Retief | Acta Theologica

    African Journals Online (AJOL)

    In the original texts of the Bible a “eunuch” is termed saris (Hebrew, Old Testament) or eunouchos (Greek, New Testament). However, both these words could apart from meaning a castrate, also refer to an official or a commander. This study therefore examines the 38 original biblical references to saris and the two ...

  13. Matthean atonement rituals | Nel | Acta Theologica

    African Journals Online (AJOL)

    It gives an operational definition of a ritual and identifies possible atonement rituals in the Gospel of Matthew up to the crucifixion of Jesus. These rituals are analysed to determine how they affect atonement through the forgiveness of sins. Since access to these rituals is only possible through the text of Matthew, Strecker's ...

  14. Conformity in Christ | Waaijman | Acta Theologica

    African Journals Online (AJOL)

    This essay investigates the notion of conformity in Christ as it is part of a comprehensive, multilayered process of transformation. In the first part it focuses on the process of transformation in creation, re-creation, conformity, love and glory. In the second part it discusses transformation in Christ by looking at conformation and ...

  15. Acta theologica supplementum 12-2009

    African Journals Online (AJOL)

    University of the Free State

    (Barnes 1798; Orr 1939; PMI 2005:16). Therefore, it is argued, the generic translation “overseer” is preferable to the specific term “bishop”. In order to investigate these arguments, it is necessary to investigate the use of the word episkopos in ancient Greek writings and the Septuagint, as well as the use of overseer as ...

  16. Acta Neuropsychiatrica; Tijdschrift voor een hedendaagse neuropsychiatrie.

    Science.gov (United States)

    Verhey, F H

    1989-09-01

    Samenvatting De psychiatrie benist op een evenwichtige combinatie van gedragswetenschappelijke (ontwikkelingspsychologische en sociale) en natuurwetenschappelijke (neuropsychiatri-sche) dementen. Ofschoon klinici werkzaam in de gezondheidszorg er vaak in slaagden dit evenwicht rede-lijk te handhaven, werd de officiële psychiatrie tot voor kort meestal nogal modieus gedomineerd door een van deze deelgebieden. Uitgroei tot volwassenheid van de psychiatrie vraagt in deze fase om een aanvulling van de in de laatste decennien sterk tot de verbeelding sprekende psychologische en sociale dementen met de verworvenhe-den van een nieuwe neuropsychiatrie. Geschetst wordt waar uit deze verworvenheden bestaan en hoe deze effectief in de psychiatrische gezondheidszorg onderwijs en onderzoek ingebouwd kunnen worden. Het binnen de psychiatrie tot ontwikkeling brengen van een toegepaste klinische psychofysiologie van essentieel belang.

  17. Acta Theologica - Vol 33, No 2 (2013)

    African Journals Online (AJOL)

    Entering the Corridors of Power: State and Church in the Reception History of Revelation · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL ... When Kingdoms are Kingdoms no more: A social-scientific reading of the Mustard Seed (Lk 13:18-19) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  18. II Actas Congreso .¿Nuevos feminismos?

    OpenAIRE

    Pinyana i Garí, M. Carme

    2005-01-01

    ÍNDICE Presentación CONSOL AGUILAR RÓDENAS I. PONENCIAS La representación de la violencia / la violencia de la representación: De Jack el Destripador a Ciudad Juárez, pasando por la pantalla de la televisión,MARÍA RUIDO. Las apostillas al cuerpo: un ámbito de debates feministas, MERI TORRAS. Mujeres jóvenes y movimientos feministas: ¿Una nueva generación de feministas?,SHAMILLAH WILSON. La doble discriminación de las lesbianas,BEATRIZ GIMENO. II. MESAS REDONDAS ...

  19. Acta Theologica - Vol 24, No 2 (2004)

    African Journals Online (AJOL)

    Skrif en Kerkorder/Scripture and church order · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A Celliers, P.J Strauss, 1-22. http://dx.doi.org/10.4314/actat.v24i2.48978 ...

  20. Acta theologica supplementum 12-2009

    African Journals Online (AJOL)

    University of the Free State

    radie 1986, De Vries, Willemyns en Burger 1994, Raidt 1980, Van der Wal 1994,. Van Zijl 1992, en Wikipedia, de vrije .... Pare wat gaan trou het, het 'n Statenbijbel as geskenk gekry. Vaders het driemaal per .... verhaal is in tyd en ruimte ver verwyder van die SuidAfrika van Du Toit. Deur gebruik te maak van buitelandse en ...

  1. Acta theologica supplementum 12-2009

    African Journals Online (AJOL)

    University of the Free State

    The Protestant antialcohol ethic and communal support networks threaten southern Mexico's labour structure where wealthy caciques rely on expensive. Catholic .... introduce a JudeoChristian notion of teleological history and progress into May an communities. By addressing Mayans as pagan communities needing Jesus.

  2. Acta theologica supplementum 12-2009

    African Journals Online (AJOL)

    University of the Free State

    even in the mind of Westerners, from a Europecentred world to a human kindcentred world. Henceforth the churches of the West would increas ingly take cognizance of the views of and developments in the younger churches. Yet even at the Second Vatican Council the voices of Third. World church leaders were still muffled ...

  3. The death of Cleopatra | Retief | Acta Theologica

    African Journals Online (AJOL)

    Fatal viper bites are characteristically associated with prominent, swollen and haemorrhagic wounds. Cobras may cause rapid death in spite of minor bite wounds, but in order to kill three adults, the snake would have to be large. Legend has it that the reptile was smuggled to Cleopatra in a small basket of figs, which would ...

  4. Acta Structilia - Vol 21, No 1 (2014)

    African Journals Online (AJOL)

    The carbon footprint and embodied energy of construction material: A comparative analysis of South African BRT stations · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J Hugo, A Barker, H Stoffberg, 45-78 ...

  5. Acta Theologica - Vol 29, No 2 (2009)

    African Journals Online (AJOL)

    The centuries-old dialogue between buddhism and christianity · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. M Clasquin-Johnson. http://dx.doi.org/10.4314/actat.v29i2.55440 ...

  6. Spirituality and contextuality | Waaijman | Acta Theologica

    African Journals Online (AJOL)

    This article discusses various historiographies of spirituality as an indication of the influence of context on spirituality. It gives an overview of the most important historiographies of spirituality. Secondly, it describes the extremes of contextuality and noncontextuality, before finally reflecting on the dialectic tension between ...

  7. What is spirituality? | Waaijman | Acta Theologica

    African Journals Online (AJOL)

    This essay provides, first of all, a historical perspective on the nature of spirituality by investigating its early forms, followed by a discussion of two approaches in the last century. It then investigates three basic forms of spirituality, concluding with an overview of elements of spirituality.

  8. bladet. Acta Periodica Rerum Interiorum Bibliotecae Universitatis

    DEFF Research Database (Denmark)

    2007-01-01

    Temanummer med billeder, interwievs og personaleberetninger om Syddansk Universitetsbiblioteks afdeling i Østergade i Odense 1968-2007. Redaktører m.m. Erik Hellerup Madsen og Søren Mogensen sammen med redaktørgruppen Projekt Fra Glemmebogen. Yderligere bidrag kan findes i Projekt Fra Glemmebogen....

  9. Acta theologica supplementum 12-2009

    African Journals Online (AJOL)

    University of the Free State

    The translation of the Zulu. New Testament and Psalms, produced in 1986 by the Bible Society of South. Africa, falls in the latter period. The mid1970s saw a breakaway from the way in which the study of trans lation was conducted. A new paradigm for the study of literary translation on the basis of a comprehensive theory ...

  10. Hippocrates: facts and fiction | Retief | Acta Theologica

    African Journals Online (AJOL)

    Hippocrates, the Father of Medicine, is reviewed as a historical person and in terms of his contribution to medicine in order to distinguish fact from fiction. Contemporary and later sources reveal that many (possibly untrue) legends accumulated around this enigmatic figure. The textual tradition and the composition of the ...

  11. Acta Theologica - Vol 35, No 1 (2015)

    African Journals Online (AJOL)

    Mission to people of other faiths in the Old Testament and Eldoret, Kenya: Some reflections for engaging Muslims within their context · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. R Omwenga, 134-152. http://dx.doi.org/10.4314/actat.v35i1.8 ...

  12. Acta Theologica 2010 Supplementum 13 Second Edition

    African Journals Online (AJOL)

    2009-12-21

    Dec 21, 2009 ... This design which has emerged from my academic drawing-board, was in- spired by my own personal ...... there has been an emphasis on the performance of good work. Volf (1991:3), amongst others, ...... against both methodological imperialism and isolated language games and does this by resting on ...

  13. Calvyn oor twyfel | Potgieter | Acta Theologica

    African Journals Online (AJOL)

    ... sinful human nature, causing anxiety and conflict in the faithful. Although it is part and parcel of Christian life, he condemns it as opposed to the will of God. He does, however, also express his compassion with those suffering under this duress. God expects the faithful to actively resist temptations of doubt and uncertainty.

  14. Acta Structilia - Vol 24, No 2 (2017)

    African Journals Online (AJOL)

    Deciphering priority areas for improving project risk management through critical analysis of pertinent risks in the Zambian construction industry · EMAIL FREE FULL ... Stakeholders' perception of critical success factors for sustainable facilities management practice in universities in sub- Saharan Africa · EMAIL FREE FULL ...

  15. Discernment in 1 Thessalonians | Sciberras | Acta Theologica

    African Journals Online (AJOL)

    This article analyses Paul's use of δοκιμάζειν in 1 Thessalonians 5:21 within the context of verbs for discernment (δοκιμάζειν, πειράζειν, διακρίνειν and their cognates). It discusses Paul's use of these verbs against the background of discernment in the Septuaginta. Paul's own understanding of discernment is then further ...

  16. Corruption: How should Christians respond? | Theron | Acta ...

    African Journals Online (AJOL)

    The results of the 2010 Corruption Perceptions Index of Transparency International indicate the seriousness of the worldwide corruption problem. Although recent decades have witnessed a global public awareness and an increase in attempts to eradicate corruption, it is an ongoing problem. It is evident that legislation is ...

  17. Eunugs in die Bybel | Retief | Acta Theologica

    African Journals Online (AJOL)

    The meaning of saris is unclear in 2 Kings 9:32, 18:17; Jeremiah 38:7-13, 39:3, 13 and Daniel 1:3, 7, 8-15. The view that Nehemiah was a ... Matthew 19:12 refers to three kinds of ";eunuchs";, viz. castrates, congenital eunuchs and those who voluntarily renounce marriage (asceticism). The latter two concepts are further ...

  18. Acta Theologica - Vol 37, No 1 (2017)

    African Journals Online (AJOL)

    Radical Orthodoxy - Panel discussion between Profs Graham Ward, John Milbank, Danie Goosen and Dr Jaco Kruger · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. D. Goosen, Jaco Kruger ...

  19. Acta Theologica - Vol 32, No 2 (2012)

    African Journals Online (AJOL)

    Reflection on the Theology of Joseph Ratzinger (Pope Benedict XVI) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J Corkery. http://dx.doi.org/10.4314/actat.v32i2.2 ...

  20. Acta theologica supplementum 12-2009

    African Journals Online (AJOL)

    University of the Free State

    of the Bible in indigenous languages — most famously into Setswana by Robert Moffat at Kuruman. Inevitably, the availability of the Bible in .... LMS was Matthew 28:1820, the Great Commission. But a further biblical text ..... with the first four chapters of Genesis, which provides the basis of thinking about creation, community, ...

  1. Acta Structilia - Vol 19, No 1 (2012)

    African Journals Online (AJOL)

    Qualitative content analysis from the lean construction perspective: A focus on supply chain management · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. F Emuze, 1-18 ...

  2. Relecturas de Boccaccio: narrativa de los Siglos de Oro, cine y teatro. Actas del Congreso Internacional Complutense (28-30 de abril de 2009), María Hernández Esteban, Marcial Carrascosa Ortega y Mita Valvassori (eds.) [Reseña de libro

    OpenAIRE

    Blanco Valdés, Carmen F.

    2011-01-01

    Reseña del libro: Relecturas de Boccaccio: narrativa de los Siglos de Oro, cine y teatro. Actas del Congreso Internacional Complutense (28-30 de abril de 2009), María Hernández Esteban, Marcial Carrascosa Ortega y Mita Valvassori (eds.), Cuadernos de Filología Italiana, Madrid, Publicaciones de la Universidad Complutense de Madrid, núm. extraordinario, 2010, 250 pp.

  3. Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

    Directory of Open Access Journals (Sweden)

    Miguel Tolosa Igualada

    2016-05-01

    Full Text Available http://dx.doi.org/10.5007/2175-7968.2016v36n2p291 Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

  4. Daniel Gallego Hernández (Ed.). Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

    OpenAIRE

    Miguel Tolosa Igualada

    2016-01-01

    Daniel Gallego-Hernández (ed.). Current Approaches to Business and Institutional Translation. Proceedings of the International Conference on Economic, Business, Financial and Institutional Translation / Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suíça: Peter Lang, 2015, 254 páginas. ISBN 978-3-0343-1656-9.

  5. Diverse expression of sucrose transporter gene family in Zea mays

    Indian Academy of Sciences (India)

    2015-03-04

    Mar 4, 2015 ... Planta 225, 907–918. Lemoine R. 2000 Sucrose transporters in plants: update on function and structure. Biochem. Biophys. Acta 1465, 246–262. Lu J. M. Y. and Bush D. R. 1998 His-65 in the proton-sucrose symporter is an essential amino acid whose modification with site-directed mutagenesis increases ...

  6. In vitro germination and structure of hard seed testa of natural ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-03-03

    Mar 3, 2008 ... 37: 165-170. Konieczny R (1995). Plant regeneration in callus culture of Trifolium nigrescens Viv. Acta. Biol. Crac. Ser. Bot. 37: 47-53. Luft JH (1961). Improvements in epoxy resin embedding methods. J. Biophys Biochem Cytol, 9: 409. MacLean NL, Nowak J (1989). Plant regeneration from hypocotyl and.

  7. Rate enhancement of the internal electron transfer in cytochrome c oxidase by the formation of a peroxide complex; its implication on the reaction mechanism of cytochrome c oxidase.

    Science.gov (United States)

    Gorren, A C; Dekker, H; Vlegels, L; Wever, R

    1988-03-09

    The oxidation of reduced cytochrome c oxidase by hydrogen peroxide was investigated with stopped-flow methods. It was reported by us previously (A.C.F. Gorren, H. Dekker and R. Wever (1986) Biochim. Biophys. Acta 852, 81-92) that at low H2O2 concentrations cytochrome a is oxidised simultaneously with cytochrome a3, but that at higher H2O2 concentrations the oxidation of cytochrome a is slower than that of cytochrome a3. We now report that for high peroxide concentrations (10-45 mM) the oxidation rate of cytochrome a increased linearly with the concentration of H2O2 (k = 700 M-1.S-1). Upon extrapolation to zero H2O2 concentration an intercept with a value of 16 s-1 (at 20 degrees C and pH 7.4) was found. A reaction sequence is described to explain these results; according to this model the rate constant (16 S-1) at zero H2O2 concentration represents the true value of the rate of electron transfer from cytochrome a to cytochrome a3 when the a3-CuB site is oxidised and unligated. However, when a complex of hydrogen peroxide with oxidised cytochrome a3 is formed, this rate is strongly enhanced. The slope (700 M-1.S-1) would then represent the rate of cytochrome a3(3+)-H2O2 complex formation. From experiments in which the pH was varied, we conclude that the reaction of H2O2 with cytochrome a3(2+) is independent of pH, whereas the electron-transfer rate from cytochrome a to cytochrome a3 gradually decreases with increasing pH. From the temperature dependence we could calculate values of 23 kJ.mol-1 and 45 kJ.mol-1 for the activation energies of the oxidations by H2O2 of cytochrome a3(2+) and cytochrome a2+, respectively. The similarity of the values that were obtained for cytochrome a oxidation both with H2O2 and with O2 as the electron acceptor suggests that the reactions share the same mechanism. In 2H2O the reactions studied decreased in rate. For the reaction of 2H2O2 with reduced cytochrome a3 in 2H2O, a small effect was found (15% decrease in rate constant

  8. The effects of methylglyoxal-bis(guanylhydrazone) on spermine binding and transport in liver mitochondria.

    Science.gov (United States)

    Toninello, A; Via, L D; Di Noto, V; Mancon, M

    1999-12-15

    This study evaluated the effect of the anticancer drug methylglyoxal-bis(guanylhydrazone) (MGBG) on the binding of the polyamine spermine to the mitochondrial membrane and its transport into the inner compartment of this organelle. Spermine binding was studied by applying a new thermodynamic treatment of ligand-receptor interactions (Di Noto et al., Macromol Theory Simul 5: 165-181, 1996). Results showed that MGBG inhibited the binding of spermine to the site competent for the first step in polyamine transport; the interaction of spermine with this site, termed S1, also mediates the inhibitory effect of the polyamine on the mitochondrial permeability transition (Dalla Via et al., Biochim Biophys Acta 1284: 247-252, 1996). In the presence of 1 mM MGBG, the binding capacity and affinity of this site were reduced by about 2.6-fold; on the contrary, the binding capacity of the S2 site, which is most likely responsible for the internalization of cytoplasmic proteins (see Dalla Via et al., reference cited above), increased by about 1.3-fold, and its binding affinity remained unaffected. MGBG also inhibited the initial rate of spermine transport in a dose-dependent manner by establishing apparently sigmoidal kinetics. Consequently, the total extent of spermine accumulation inside mitochondria was inhibited. This inhibition in transport seems to reflect a conformational change at the level of the channel protein constituting the polyamine transport system, rather than competitive inhibition at the inner active site of the channel, thereby excluding the possibility that the polyamine and drug use the same transport pathway. Furthermore, it is suggested that, in the presence of MGBG, the S2 site is able to participate in residual spermine transport. MGBG also strongly inhibits deltapH-dependent spermine efflux, resulting in a complete block in the bidirectional flux of the polyamine and its sequestration inside the matrix space. The effects of MGBG on spermine accumulation

  9. Expansion of the Bactericidal/Permeability Increasing-like (BPI-like protein locus in cattle

    Directory of Open Access Journals (Sweden)

    McEwan John C

    2007-03-01

    Full Text Available Abstract Background Cattle and other ruminants have evolved the ability to derive most of their metabolic energy requirement from otherwise indigestible plant matter through a symbiotic relationship with plant fibre degrading microbes within a specialised fermentation chamber, the rumen. The genetic changes underlying the evolution of the ruminant lifestyle are poorly understood. The BPI-like locus encodes several putative innate immune proteins, expressed predominantly in the oral cavity and airways, which are structurally related to Bactericidal/Permeability Increasing protein (BPI. We have previously reported the expression of variant BPI-like proteins in cattle (Biochim Biophys Acta 2002, 1579, 92–100. Characterisation of the BPI-like locus in cattle would lead to a better understanding of the role of the BPI-like proteins in cattle physiology Results We have sequenced and characterised a 722 kbp segment of BTA13 containing the bovine BPI-like protein locus. Nine of the 13 contiguous BPI-like genes in the locus in cattle are orthologous to genes in the human and mouse locus, and are thought to play a role in host defence. Phylogenetic analysis indicates the remaining four genes, which we have named BSP30A, BSP30B, BSP30C and BSP30D, appear to have arisen in cattle through a series of duplications. The transcripts of the four BSP30 genes are most abundant in tissues associated with the oral cavity and airways. BSP30C transcripts are also found in the abomasum. This, as well as the ratios of non-synonymous to synonymous differences between pairs of the BSP30 genes, is consistent with at least BSP30C having acquired a distinct function from the other BSP30 proteins and from its paralog in human and mouse, parotid secretory protein (PSP. Conclusion The BPI-like locus in mammals appears to have evolved rapidly through multiple gene duplication events, and is thus a hot spot for genome evolution. It is possible that BSP30 gene duplication is a

  10. Molecular basis of proton uptake in single and double mutants of cytochrome c oxidase

    Energy Technology Data Exchange (ETDEWEB)

    Henry, Rowan M; Caplan, David; Pomes, Regis [Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, M5G 1X8 (Canada); Fadda, Elisa, E-mail: pomes@sickkids.ca [Department of Chemistry, University of Galway (Ireland)

    2011-06-15

    Cytochrome c oxidase, the terminal enzyme of the respiratory chain, utilizes the reduction of dioxygen into water to pump protons across the mitochondrial inner membrane. The principal pathway of proton uptake into the enzyme, the D channel, is a 2.5 nm long channel-like cavity named after a conserved, negatively charged aspartic acid (D) residue thought to help recruiting protons to its entrance (D132 in the first subunit of the S. sphaeroides enzyme). The single-point mutation of D132 to asparagine (N), a neutral residue, abolishes enzyme activity. Conversely, replacing conserved N139, one-third into the D channel, by D, induces a decoupled phenotype, whereby oxygen reduction proceeds but not proton pumping. Intriguingly, the double mutant D132N/N139D, which conserves the charge of the D channel, restores the wild-type phenotype. We use molecular dynamics simulations and electrostatic calculations to examine the structural and physical basis for the coupling of proton pumping and oxygen chemistry in single and double N139D mutants. The potential of mean force for the conformational isomerization of N139 and N139D side chains reveals the presence of three rotamers, one of which faces the channel entrance. This out-facing conformer is metastable in the wild-type and in the N139D single mutant, but predominant in the double mutant thanks to the loss of electrostatic repulsion with the carboxylate group of D132. The effects of mutations and conformational isomerization on the pKa of E286, an essential proton-shuttling residue located at the top of the D channel, are shown to be consistent with the electrostatic control of proton pumping proposed recently (Fadda et al 2008 Biochim. Biophys. Acta 1777 277-84). Taken together, these results suggest that preserving the spatial distribution of charges at the entrance of the D channel is necessary to guarantee both the uptake and the relay of protons to the active site of the enzyme. These findings highlight the interplay

  11. Protective effect of deoxyribonucleosides on UV-irradiated human peripheral blood T-lymphocytes: possibilities for the selective killing of either cycling or non-cycling cells.

    Science.gov (United States)

    Green, M H; Waugh, A P; Lowe, J E; Harcourt, S A; Clingen, P H; Cole, J; Arlett, C F

    1996-02-19

    Non-cycling human T-lymphocytes from normal subjects show a 10-fold greater sensitivity than fibroblasts to UV-B (280-315 nm) irradiation from a Westinghouse FS20 lamp, but only a 2.7-fold greater sensitivity to UV-C (254 nm) irradiation. Hypersensitivity is associated with a deficiency in the rejoining of excision breaks. Non-cycling T-lymphocytes have extremely low deoxyribonucleotide pools. Addition to the medium of the four deoxyribonucleosides, each at a concentration of 10(-5) M, substantially increases survival and reduces the persistence of excision-related strand breaks following UV-B or UV-C irradiation (Yew and Johnson (1979) Biochim. Biophys. Acta 562, 240-241; Green et al. (1994) Mutation Res., 315, 25-32). UV-resistance of T-lymphocytes is also increased by stimulating the cells into cycle. The addition of deoxyribonucleosides does not further enhance survival of cycling cells and they do not reach the level of resistance achieved by non-cycling cells in the presence of deoxyribonucleosides. We suggest that two opposing effects are in operation. Cells out of cycle can show increased resistance to DNA damage in the absence of division but they also have reduced deoxyribonucleotide pools, which may limit DNA repair. With UV-B irradiation, the exceptionally low dNTP pools in non-cycling T-lymphocytes cause this second effect to predominate. In contrast, with ionising radiation, which forms highly cytotoxic double-strand breaks, non-cycling human T-lymphocytes are slightly more resistant than fibroblasts. Non-cycling cells such as T-lymphocytes should be especially sensitive to agents which produce a high proportion of read excisable damage, but should show normal resistance to agents which highly toxic lesions. It may be possible by choice of DNA damaging agent and manipulation of cellular deoxyribonucleotide pools, to choose regimes which will selectively kill either cycling or non-cycling cells and to improve the efficacy of standard therapeutic

  12. Mechanism for adaptive modification during cold acclimation of phospholipid acyl chain composition in Tetrahymena. II. Activities of 2-acyl-sn-glycerol-3-phosphorylcholine and 2-acyl-sn-glycerol-3- phosphorylethanolamine acyltransferases involving the reacylation.

    Science.gov (United States)

    Yoshioka, S; Kameyama, Y; Nozawa, Y

    1984-03-27

    The deacylation-reacylation process is very important for the alteration of phospholipid fatty acyl composition on lowering of growth temperature in Tetrahymena pyriformis (Kameyama, Y., Yoshioka, S. and Nozawa, Y., (1984) Biochim. Biophys. Acta 793, 28-33). Microsomes isolated from Tetrahymena cells have reacylation activities not only for 1-acyl-sn-glycerol-3-phosphorylcholine (1-acyl-GPC) and 1-acyl-sn-glycerol-3-phosphorylethanolamine (1-acyl-GPE) but also for 2-acyl-GPC and 2-acyl-GPE. Unsaturated fatty acyl-CoAs were in general much better substrates than saturated fatty acyl-CoAs for acylations of 1-acyl-GPC and 1-acyl-GPE. The acylation rates for 1-acyl-GPE were almost the same in palmitoleoyl-CoA, oleoyl-CoA, linoleoyl-CoA and gamma-linoleoyl-CoA. However, the acylation activity for 1-acyl-GPC was more than 2-fold higher with palmitoleoyl-CoA than with any other unsaturated fatty acyl-CoAs. In contrast, both 2-acyl-GPC and 2-acyl-GPE acyltransferases did not show a distinct preference for various acyl-CoAs, although palmitoyl-CoA was incorporated into both 2-acylphospholipids at higher rates than into 1-acylphospholipids. These specificities for various acyl-CoAs of 1-acyl- and 2-acyl-GPC and 1-acyl- and 2-acyl-GPE acyltransferases were not changed in the microsomes isolated from cells grown isothermally at 39 degrees C and 15 degrees C and cells shifted from 39 degrees C to 15 degrees C. However, the acylating ratio of linoleoyl-CoA to palmitoyl-CoA, which were chosen as typical unsaturated and saturated fatty acyl-CoAs, in the microsomes from cells grown at 15 degrees C was 1.5-3.0-times higher than in the microsomes from 39 degrees C-grown cells in four acyltransferase activities. These results suggest that the changes of acyl-CoA specificities in reacylation enzyme activities during temperature down-shift would make little contribution to the increase in unsaturated fatty acids in phospholipids, although reacylating enzymes from isothermally grown

  13. Spanish participation in the Conference on Security and Cooperation in Europe (CSCE: contributions to the Helsinki Final Act | La participación española en la Conferencia para la Seguridad y la Cooperación en Europa (CSCE: aportaciones al Acta Final de Helsinki

    Directory of Open Access Journals (Sweden)

    Ana Capilla Casco

    2015-12-01

    Full Text Available The Conference on Security and Cooperation in Europe announcement provided Francoist Spain an excellent opportunity to join a multilateral forum aiming to promote security in Europe as well as a détente between the West and the Soviet Union. Spanish diplomacy, despite the relative international isolation of the country and the limits derived from the authoritarian nature of the Regime, designed a negotiation strategy contributing to gaining visibility and providing valuable contributions to the Final Act, such as the incorporation of the text on Mediterranean security. They also reached a wording of the Act principles agreeable to Spain’s interest and to the progress made in United Nations. On the basis of the analysis of the Spanish delegation reports, this article studies both the lights of the work done in Helsinki and Geneva and its shades, the latter being identified with the red lines established by the Francoist Regime. In terms of human rights and especially regarding free circulation and exchange of information. | La convocatoria de la Conferencia para la Seguridad y la Cooperación en Europa brindó una ocasión excelente a la España franquista para poder participar en un foro multilateral destinado a promover la seguridad en Europa y la distensión entre Occidente y la Unión Soviética. La diplomacia española, pese al relativo aislamiento al que seguía sometido el país y las limitaciones que se derivaban de la naturaleza autoritaria del Régimen, trazó una estrategia negociadora que le permitió ganar visibilidad y realizar aportaciones destacadas al Acta Final, como la incorporación del texto sobre la seguridad en el Mediterráneo. Del mismo modo, logró que la redacción de los principios del Acta fuera conforme a los intereses de España y se preservaran los logros alcanzados en Naciones Unidas. Este artículo tiene por objeto estudiar, a partir del análisis de los informes redactados por la propia delegación espa

  14. Untitled

    Indian Academy of Sciences (India)

    (CECRI), 5.477. Drudy W D and DeKorte J M 1983 Inorg, Chem. 22 121, and references cited therein. Iyanagi T, Yamazaki I and Anan K F 1985 Biochem. Biophys. Acta 255 806. Kuncher NR 1968 Nature (London) 217 539. Macartney D H. McAuley A and Olubuyide O R 1985 Inorg. Chem. 24.307. Miller J D 1968 J. Chem.

  15. Isolation of a Toxin from Venom of Wagler’s Pit Viper Trimeresurus wagleri

    Science.gov (United States)

    1990-01-31

    activity was performed following the protocol of MARINETTI (1965). Hemolytic activity was assayed by using rat erythrocytes accoding to the method of...activity ( MARINETTI , 1965) detected weak PLA activity in the Superose 12 lethal pool. Bio-Rex 70 isolation of lethal toxin from Suoerose-12 pool...head of bacteriophage T4. Nature 227, 680-685. MARINETTI , G. V. (1965). The action of phospholipase A on lipoproteins. Biochimie Biophys. Acta .98

  16. Radical Orthodoxy - Its ecumenical vision | Ward | Acta Theologica

    African Journals Online (AJOL)

    The first book in the Series Radical Orthodoxy (RO) was not meant to be programmatic or set out to change the direction of modern theology. There are certain shared sensibilities among its authors and, principally, an ecumenical vision. This article sketches the nature of that ecumenical vision that begins with the way in ...

  17. Quibus annis comoediae plautinae primum actae sint quaeritur

    NARCIS (Netherlands)

    Schutter, Klaas Herman Eltjo

    1952-01-01

    De Plauti nominibus diu inter viros doctos fuit controversia, quae adhuc, eheu! non tot diiudicata est. In veteribus editionibus poeta noster vocatur M. Accius Plautus, quae nomina primum inveniuntur in editionibus, quae saeculo XV in terra Italia prodierunt, neque tamen ullius codicis lectione

  18. Die Afrikaans van die bybelvertaling van 1933 1 | Steyn | Acta ...

    African Journals Online (AJOL)

    The first translators of the Bible had to start their work before the standardisation of Afrikaans. This article firstly explores the difficulties encountered by the Bible translators in breaking with the language of the Statenbijbel. Secondly, it is indicated how translators were able to utilise the insights of linguists and language ...

  19. Interview with Piet J. Naudé | Laubscher | Acta Theologica

    African Journals Online (AJOL)

    ... The Netherlands. His thesis explored the relation between theory and practice in Latin-American Liberation Theologies and the work of Johann Baptist Metz. As Humboldt scholar, he later built a special academic relation with Michael Welker in Heidelberg (Germany) and with the Centre for Theological Inquiry at (USA).

  20. Identity claims, texts, Rome and Galatians | Punt | Acta Theologica

    African Journals Online (AJOL)

    This contribution explores the interplay between Paul's use of the Scriptures of Israel and the imperial setting in claims about Abraham and the negotiation of identity in the Galatians letter. The letter, from Paul's perspective, is testimony to fierce contestation of identity and finds him engaged in describing, defining and ...

  1. The book, deconstruction, and the religious sign | Gheitury | Acta ...

    African Journals Online (AJOL)

    In this article, I investigate a possibility in the structure of the Qur'an for rethinking the usually forgotten issue of the religious sign. This is where deconstruction , guided by acertain otherness or transcendence, renders all God's attributes as unthinka ble. Thus, God's presence is not the opposite of absence and his will is not ...

  2. Die Nuwe Testament en seksualiteit | Van Zyl | Acta Theologica

    African Journals Online (AJOL)

    The new testament and sexuality. This article deals with sexuality in the New Testament. In a first movement the line of thought is pursued in which sex in the New Testament is presented as something legitimate and enjoyable. Celibacy also comes into focus. In a next movement forbidden practices are highlighted: ...

  3. The Heidelberg Catechism on human sin and misery | Baard | Acta ...

    African Journals Online (AJOL)

    The Heidelberg Catechism's section on Sin and Misery does not provide a moralistic or legalistic perspective on the human condition. Instead, it offers, in abbreviated format, a restatement of the doctrine of original sin, which points to sin as a condition and not just an act. As such, it invites us to think more deeply about the ...

  4. Die Bybel steeds in diskussie: 'n dekade later | Doubell | Acta ...

    African Journals Online (AJOL)

    The Bible still in discussion: a decade later. This article highlights the relationship between theology and context. In 1990 politics played a considerable role in South Africa. Authors such as F.E. Deist argued that one's point of departure, whether theological or political, is crucial. In 1991 Deist wrote an article on the ...

  5. An investigation into Calvin's use of Augustine | Han | Acta Theologica

    African Journals Online (AJOL)

    This article briefly investigates the use of Augustine as an authority from the early church in John Calvin's writings. Calvin frequently referred to and quoted Augustine in his writings. Augustine undoubtedly exerted an influence on Calvin's views and arguments. This article traces Calvin's use of Augustine in his writings ...

  6. The language ecology of a new Afrikaans Bible | Ponelis | Acta ...

    African Journals Online (AJOL)

    Three sets of codes are germane to a current Afrikaans Bible translation: Dutch, English and varieties of Afrikaans, especially Standard Afrikaans. Dutch was established as a local language of culture in the Dutch era from 1652 to 1806. The sweeping transformation of Cape society by British colonial rule gave great impetus ...

  7. Gelukkig hij die uw kinderen zal grijpen' | Peels | Acta Theologica

    African Journals Online (AJOL)

    Happy is he who seizes your infants…. Hermeneutical and biblical-theological positioning of the Old Testament imprecations. The Old Testament contains many prayers for the shaming, punishment or destruction of the godless, especially in the Psalms. This imprecatory prayer, which still forms one of the most troublesome ...

  8. Etiese Besluitneming Volgens 1 Johannes | van der Watt | Acta ...

    African Journals Online (AJOL)

    http://dx.doi.org/10.4314/actat.v33i2.12 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES... for Researchers · for Journals · for Authors · for Policy Makers ...

  9. Paul, military imagery and social disadvantage | Punt | Acta ...

    African Journals Online (AJOL)

    In the past, attention for the social position or standing of the early Jesus followers was overrun by concerns for the theological and religious dimensions of those communities. The role of the Roman Empire and the impact of its military forces on the lives of people have generated even less attention. Paul's use of military ...

  10. Spirituality, theology and the critical mind | de Villiers | Acta Theologica

    African Journals Online (AJOL)

    This essay investigates aspects of the critical nature of spirituality as a discipline. It first analyses how a recent publication on philosophy critiques the role of the critical mind in contemporary philosophy and how it reclaims spirituality as solution for what went wrong. In a next section it discusses similar criticism of traditional ...

  11. Onderscheiding der Geesten in Marcus | Welzen | Acta Theologica

    African Journals Online (AJOL)

    Unclean spirits deprive human beings of their identity, they dehumanize them and in the end they destroy them. Their uncleanness is the opposite of the holiness of God. It is possible to read the gospel of Mark as the struggle of Jesus with demons. His death and resurrection is the victory over their uncleanness. When it is ...

  12. Jesus and “the Daniel code” | Thom | Acta Theologica

    African Journals Online (AJOL)

    It is suggested that Jesus, who understood his Messianic calling in the light of the OT prophecies, utilized their symbolic apocalyptic language in his prophetic discourse. From this perspective Matthew 26:64 sheds important light on the meaning of Matthew 24:30b, i.e. that those who rejected him would realize, within a ...

  13. Jesus, history and the gospels: research | Moyise | Acta Theologica

    African Journals Online (AJOL)

    This article considers the reasons why modern scholars have felt the need to go behind the four Gospels and search for the historical Jesus. After a short discussion on methodology, especially the criteria used to detect the earliest and most reliable traditions about Jesus, a number of recent proposals are discussed: Jesus ...

  14. A new leadership for a new ecclesiology | Mothoagae | Acta ...

    African Journals Online (AJOL)

    While many berate the poor level of leadership in the Church, it is noticeable that the same complaint is made about leadership in the corporate world. It is the authors' contention that the new ecclesiology that has been spoken and written about during the past decades cannot be implemented until there is a change in the ...

  15. Godsdiens: Middel tot verslawing of tot heling? | Coetzer | Acta ...

    African Journals Online (AJOL)

    There are two sides to religion, on the one hand the threat that implies emotional pain and addiction, on the other hand the healing and liberating effect of a balanced and healthy religion. In this article the focus is on the former. Factors which render people vulnerable to spiritual addiction are put on the table. Similarities ...

  16. The misnomers of spiritual 'directing' and 'coaching' | Pienaar | Acta ...

    African Journals Online (AJOL)

    coaching' related to its general use, but spiritual 'coaching', in particular. Directing and coaching are said to be misnomers that communicate directivity instead of primarily being situated in a non‑directive style of engagement. Within the author's ...

  17. Wat is 'n gereformeerde liturgie? | Rensburg | Acta Theologica

    African Journals Online (AJOL)

    , some protagonists for renewal embrace anything new that works, while on the other hand traditionalists reject attempts to renew the liturgy, arguing that such efforts go against the reformed liturgy. The question, however, is raised: “What is a ...

  18. Theft and robbery in chrysostom's time | Stander | Acta Theologica

    African Journals Online (AJOL)

    The aim of this article is to study what Chrysostom said about theft and robbery in his community. His homilies on the New Testament will be scrutinized for information on this negative feature of the ancient world, since homilies are always important sources for information on social issues. It becomes clear that ...

  19. Poverty Relief or Poverty Eradication? | Kritzinger | Acta Theologica

    African Journals Online (AJOL)

    The author challenges the reader to make two mindshifts: from a focus on poverty relief to an emphasis on poverty eradication; and from viewing the poor as the objects of poverty alleviation to accepting them as the subjects of poverty eradication. The case is argued and a practical approach towards poverty eradication is ...

  20. A new framework for Bible translation | Wilt | Acta Theologica

    African Journals Online (AJOL)

    ... as well as translators and choosing a particular translation approach in terms of mutually agreed upon goals. The Bible translation process may involve not just producing a text to represent the sacred text, but also supplementary texts to enhance understanding and appreciation of both the translation and the translated.

  1. Nota editorial: Acta final de la X conferencia sanitaria panamericana

    Directory of Open Access Journals (Sweden)

    Facultad de Medicina Revista

    1938-10-01

    Fueron designados: Secretario General de la Conferencia el Doctor Jorge Salcedo Salgar, Secretario Ejecutivo el Doctor Aristides A. Moll y Secretarios los Doctores Raul Godinho, Rulx León, Edward C. Ernst y Pedro Machado.

  2. Lead poisoning in ancient Rome | Retief | Acta Theologica

    African Journals Online (AJOL)

    A grape juice concentrate (sapa) commonly used as a sweetener was prepared by preference in lead containers. Although Roman writers commented on the toxicity of lead, classic chronic lead poisoning was first described only in the 7th century AD. Skeletal lead content increased significantly in the Roman era, but ...

  3. Happiness in the Psalms | McConville | Acta Theologica

    African Journals Online (AJOL)

    The article enquires into the nature of happiness or well-being in the Old Testament Psalms. It considers first the Psalms' use of 'happiness' language, then goes on to seek a broader basis for the enquiry in key concepts such as freedom and justice, making some comparisons with Greek ideas. Finally it seeks to build up a ...

  4. Paupertas (poverty) in John Calvin's Institutes | Britz | Acta Theologica

    African Journals Online (AJOL)

    ... to a temporal interim divine involvement. He cautiously upholds a reverent distance in respect of God's knowledge. However, when considering true and credible knowledge of God, the pastor withholds nothing from the splendour of the teaching of Scripture in this regard. In his inscrutable Deitas Dei the Father of Christ is, ...

  5. Discernment in Origen of Alexandria | Decock | Acta Theologica

    African Journals Online (AJOL)

    As such it is able to accept divine guidance from the Holy Spirit and the Logos in order to assess the movements of the soul and to manage these correctly so that the soul may preserve what is good and continue to strive for better things. As the “intelligence” is created after the image of God, the Logos, its fulfilment lies in a ...

  6. Kom ons skryf 'n Psalm! | Snyman | Acta Theologica

    African Journals Online (AJOL)

    psalms of the setting in life (Sitz im Leben) of the psalms. Due to the personal nature of the psalms, the exact setting in life was even deliberately obscured. This should caution modern day researchers of the canonical Psalms to be mindful of the fact ...

  7. Egyptian personal piety and Israel's wisdom literature | Fischer | Acta ...

    African Journals Online (AJOL)

    This article evaluates the movement of Egyptian personal piety and its relation to Israelite wisdom texts. Hymns and prayers of personal piety developed in the New Kingdom at the same time as "heretic" Harpers' songs and love songs. The personal piety affected also the genre of instructions. The instruction of Amenemope ...

  8. Towards a Spirituality of Peace | De Villiers | Acta Theologica

    African Journals Online (AJOL)

    This article contributes towards designing a Spirituality of Peace within Spirituality as a discipline. It first analyses the increasing attention to violence and peace generally and within religious contexts specifically. It then critically evaluates some approaches that view violence and peace as moral issues and shows how these ...

  9. Biblical Metaphor: The Cosmic Garden Heritage | Green | Acta ...

    African Journals Online (AJOL)

    An inquiry into the nature of metaphor, as it has evolved since Aristotle and particularly in the late twentieth century, allows fresh consideration of biblical texts. Using as a sample trope the ancient Near Eastern and biblical figure of the cosmic garden where humans live with the gods until they are exiled, the article works out ...

  10. Persecution in the book of Revelation | De Villiers | Acta Theologica

    African Journals Online (AJOL)

    In this article attention will be given to scholarly interpretations of persecution in Revelation with special attention to their theoretical, hermeneutical and theological implications. After an introductory discussion of the traditional interpretation of a ";real"; persecution in a Domitianic setting, attention will be given to the recent ...

  11. Narrative preaching - yet another perspective | Van Rensburg | Acta ...

    African Journals Online (AJOL)

    The theme of narrative preaching has been widely discussed for more than a decade. However, only recently did the interest in this form of communication of the gospel of Jesus Christ become apparent within the congregational context. Ministers increasingly find it necessary to adopt a new approach in preaching.

  12. Open-Ended Narrative and Moral Formation | Klaasen | Acta ...

    African Journals Online (AJOL)

    The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

  13. Narrative temporality and Johannine symbolism: research | Ito | Acta ...

    African Journals Online (AJOL)

    ? To investigate this is the purpose of this article. The notion of narrative temporality is not new in the study of Biblical texts. However, there have not been many studies which make this notion their main thrust. Rather, generally speaking, it has ...

  14. Assessment of wear facets produced by the ACTA wear machine

    DEFF Research Database (Denmark)

    Benetti, Ana R; Larsen, Liselotte; Dowling, Adam H

    2016-01-01

    the 2D profile technique ranks RBC materials in terms of in-vitro wear performance. CLINICAL SIGNIFICANCE: Confidence in the wear volume measurements can only be achieved if the wear facet is analysed with sufficient resolution using a 3D digital measurement technique. However, the employment of 2D....... The mean wear depth was measured using the traditionally employed 2D and compared with the 3D profilometric (digital) techniques. Data were submitted to analyses of variance, Tukey's post hoc tests and Independent Samples Student's t-tests (where appropriate) at p... for mean wear depth calculations were similar whether the 2D or 3D techniques were employed. However, the mean wear depth values obtained from the 3D digital technique were significantly increased for two of the five RBC materials compared with the 2D methodology. The total volumetric wear data provided...

  15. Symbolism in the Samaria ivories and architecture | Pienaar | Acta ...

    African Journals Online (AJOL)

    Situated at the crossroads of great nations, the Land of Israel was exposed to numerous external influences. Samaria, the capital city of Northern Israel, was also situated on a major trade route. Various expeditions uncovered approximately 500 pieces of carved ivory in the palace complex at Samaria. According to the motifs ...

  16. Abraham in Galatians and in Genesis | Snyman | Acta Theologica

    African Journals Online (AJOL)

    Three promises are made to Abraham in Genesis 12:1-3: land, progeny and blessing. It is interesting that, in each one of the passages investigated, emphasis is laid mainly (but not exclusively) on one of the promises. In Genesis 12-25, attention is paid to the promise of land and on Abraham as a blessing to the nations, but ...

  17. Diseases and causes of death among the Popes | Retief | Acta ...

    African Journals Online (AJOL)

    ... terminal kidney disease, gallstones, cancer, dysentery, the plague, lung infection, gangrene of a leg, abscesses, depression or debilitating psychiatric illness. Unnatural causes comprise inter alia assassination, death in prison or in exile, casualties of war or public violence, poisoning and stoning during street violence.

  18. Power and authority in Matthew's gospel | Viljoen | Acta Theologica

    African Journals Online (AJOL)

    Besides the strenuous relation of Matthew's community with non-Christian kinfolk, his text also reveals an underlying conflict with Roman Imperial ideology. Herod, Antipas and Pilate specifically impersonate this foreign domination. Apparently these figures have unlimited power which leaves Jesus and his followers as ...

  19. The Reformed doctrine of irresistible sanctification | Partee | Acta ...

    African Journals Online (AJOL)

    The Reformed confession of "Grace Alone" obviously involves the doctrines of faith, election, justification and perseverance. The conception of irresistible grace is comfortably applied to the same doctrines. However, sanctification is a special case in that the theological focus shifts from divine action to human effort.

  20. 'n Gereformeerd-narratiewe pastorale terapie | Bezuidenhout | Acta ...

    African Journals Online (AJOL)

    Narrative therapy is usually connected with a post-modern paradigm like Social Constructionism. However, for some researchers and therapists post-modernity is not acceptable, since the use of such a narrative therapy could construe many contrasting points of departure in contrast to a biblical based pastoral therapy.

  1. The death of Alexander the Great | Retief | Acta Theologica

    African Journals Online (AJOL)

    The circumstances of Alexander's death are reviewed. Since contemporary sources vary in their accounts of the reason for his death, they are briefly reviewed and assessed. The account of Alexander's final illness is then discussed as recorded in the King's Journal and the Liber de morte testamentumque Alexandri Magni.

  2. Skrif en Kerkorder/Scripture and church order | Celliers | Acta ...

    African Journals Online (AJOL)

    This enables the congregation to adhere to its calling for obedience, love, and witness, so that the church can continue to exist. The outlines of the nature and order of the church should be addressed in all church orders to avoid pragmatism and arbitrariness on the one hand, and to create space for the various demands of ...

  3. Tumours and cancers in Graeco-Roman times | Retief | Acta ...

    African Journals Online (AJOL)

    In Hippocratic literature tumours were mainly classified as karkinômata, phumata and oidêmata. Phumata included a large variety of tumours, inflammatory and neoplastic in origin, and mostly benign (in modern terms), whilst oidêmata were soft, painless tumours and even included generalised oedema (dropsy). Although ...

  4. Calvin and other religions: research | Potgieter | Acta Theologica

    African Journals Online (AJOL)

    Widely differing views on ways leading to true knowledge of God is at present characteristic of discussions in the sphere of religion. Although Calvin worked in a completely different scene, he has laid down certain principles based on his interpretation of Holy Scripture that may contribute to current theological thought on ...

  5. Contours of Biblical spirituality as a discipline | Welzen | Acta ...

    African Journals Online (AJOL)

    ... divine human relational process. A dialogue of spirituality and exegesis is needed. For doing research a threefold competence is needed: in exegesis, in spirituality and in the integration of these two. The final section is about intertextuality. Intertextuality may help to understand the spiritual process in reading biblical texts.

  6. Lead poisoning in ancient Rome | Retief | Acta Theologica

    African Journals Online (AJOL)

    ... classic chronic lead poisoning was first described only in the 7th century AD. Skeletal lead content increased significantly in the Roman era, but peaked at a level only 41-47% of that of modern Europeans. The authors thus suggest that chronic lead poisoning did not contribute significantly to the fall of the Roman Empire ...

  7. Morality and religion in African thought | Nel | Acta Theologica

    African Journals Online (AJOL)

    ... religion is the foundation of African morality can only be partially endorsed when one grants space for hybrid moral constructions between Christianity and indigenous religion. However, African morality is not necessarily based on religion or faith, but on the beneficiary values of collective family and community well-being, ...

  8. Calvyn oor die verskynsel van demonologie | Coetzee | Acta ...

    African Journals Online (AJOL)

    4:1; Rev. 16:13, 14). This truth can already be observed in increasing occultism, witchcraft and other forms of demonology in Europe and in Africa, where traditional African culture plays a decisive role. In order to combat demonology from a Reformed point of view, it is important to note John Calvin's opinion and approach.

  9. Reading Scripture through a mystical lens | Kourie | Acta Theologica

    African Journals Online (AJOL)

    Within this paradigm shift, the importance of a spiritual reading of scripture has now come to the fore. More specifically, reading scripture through a mystical lens, as originally seen, inter alia, in the works of Origen, has taken its place, if not centre stage, at least on the stage, and no longer in the wings. Utilising the insights of ...

  10. Thomas Aquinas: On Law, Tyranny and Resistance | Swartz | Acta ...

    African Journals Online (AJOL)

    Thomas Aquinas's notion on law, tyranny and resistance served as a limitation on governmental powers. When those who bear the law command things which exceed the competence of such authority, the subject is free to obey or disobey. The function of the law culminates in two maxims: quantum ad vim coactivam legis ...

  11. Contours of Biblical spirituality as a discipline | Welzen | Acta ...

    African Journals Online (AJOL)

    Three approaches are used for coming towards a definition of Biblical spirituality. The first approach is from lived spirituality. We see always a bipolarity of text and reader. The reader attributes meaning to the text guided by the data of the text. The second approach is the analysis of literature discussing Biblical spirituality.

  12. The valuation of commercial grain silos | Winckler | Acta Structilia

    African Journals Online (AJOL)

    A grain silo is a unique form of real estate because of its construction, use and income generation. The study is based on vertical concrete silos built for the sole purpose of storing grain. Silos are, in essence, income-producing properties, but because the tenant is the owner of grain and oilseed, the income produced by the ...

  13. Diseases and causes of death among the Popes | Retief | Acta ...

    African Journals Online (AJOL)

    The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

  14. Acta Theologica 2005: 1 RESENSIES/REVIEWS Trouble in the ...

    African Journals Online (AJOL)

    produce and without the spiritual motives of bygone ages. Eleven years later this would ultimately ... people, “warm flesh of relationship and common spirituality over the cold bones of Church law, polity, and .... that should have been “sex roles” or “grammar issues” when the Queen's. English was still in vogue in England.

  15. Snake and staff symbolism in healing | Retief | Acta Theologica

    African Journals Online (AJOL)

    The Asclepian emblem has been associated with health care since the 5th century BC when Asclepius became accepted by the Greeks as the god of healing. Whether he was also an historical figure as healer in earlier ages is less certain. The origin of the double-snake emblem is shrouded in the mists of antiquity.

  16. Sociedad de Estudios de Patología Quirúrgica de la Facultad de Medicina de Bogotá: estatutos: Estudio e Investigación. Reglamento: Tolerancia por las ideas ajenas (Acta de los días 4 y 11 de junio

    Directory of Open Access Journals (Sweden)

    Roberto N. Ezpeleta H.

    1932-11-01

    Full Text Available El día 4 de junio a las 10 de la mañana se reunió la "Sociedad de Estudios de Patología Quirúrgica" en el salón de proyecciones adjunto al Laboratorio de Rayos X del Hospital. Presidió la sesión el Profesor Jorge E. Cavelier. Asistieron a ella los Profesores Corpas y Salgar, y los doctores Herrera Salgar y Jiménez. Suárez Una vez leída el acta de la sesión anterior, el doctor Herrera Salgar presentó un curioso caso sobre apéndice doble, dando una relación de él y mostrando unas placas anatomo-patológicas muy demostrativas. En seguida tomó la palabra el Profesor Corpas quien se refirió al caso presentado por el doctor Herrera Salgar, caso que, dijo, era tanto más interesante cuanto que se refería a una apendicitis crónica, pues muchas veces se presentaban falsos apéndices dobles. en las apendicitis agudas en las que el apéndice sufre a veces una especie de estrangulación cuya parte libre es injertada en el ciego semejando un apéndice doble. Dijo que el apéndice tenía por objeto suministrar una hormona cuyo papel es activar el peristaltismo intestinal, lo cual se puede comprobar por la constipación habitual de que son víctimas los apendicectomizados. Hizo referencias a las anomalías en la especie humana, como manifestaciones de evolución regresiva, y mostró cómo en el caso particular de apéndice doble éste estan frecuente en los hervíboros.

  17. Beyond the antioxidant: the double life of vitamin C.

    Science.gov (United States)

    De Tullio, Mario C

    2012-01-01

    . 159-172). All this has very little to do with the celebrated role of ascorbic acid (ASC) as an antioxidant. So, if the fate of ASC had to be found in its name, its role in the prevention of scurvy (i.e. beyond the antioxidant function) should be considered its main feature. But, in spite of more than 80 years of extensive research (34,424 hits in a PubMed query on January 6 2007), an unprecedented popularity among the general public, an estimated market of several billion dollars (Hancock RD, Viola R (2005) Improving the nutritional value of crops through enhancement of l-ascorbic acid (vitamin C) content: Rationale and biotechnological opportunities. J Agr Food Chem 53:5248-5257), we should honestly conclude that the fate of vitamin C is still in the first name it received, many years ago: we still ignore much of its actual relevance in cell metabolism, although we are progressively getting aware of the many facets of this fascinating molecule, and its direct involvement in the regulation of apparently unrelated pathways (Arrigoni O, De Tullio MC (2002) Ascorbic acid, much more than just an antioxidant. Biochim Biophys Acta 1569:1-9; De Tullio MC, Arrigoni O (2004) Hopes, disillusions and more hopes from vitamin C. Cell Mol Life Sci 61:209-219; Duarte TL, Lunec J (2005) When is an antioxidant not an antioxidant? A review of novel actions and reactions of vitamin C. Free Rad Res 39:671-686). Recent data on ASC involvement in cell signalling and gene expression open new perspectives, that will be presented and discussed in this chapter.

  18. Poly(Beta-Hydroxybutyrate) Stereoisomers: A Model Study of the Effects of Stereochemical and Morphological Variables on Polymer Biological Degradability

    Science.gov (United States)

    1992-01-01

    the samples were of Biophys. Acta 1M, 880, 46. comparable molecular weights. Therefore, the preference (21) Brucato, C. L. Ph.D. Thesis , University of... Thesis , University of Lowell, MA, 1991.(45) See ref 22, Materials and Methods. The enzyme purificationConsortium at the University of Mia.,•chusetts...Capon, R. J.; Dunlop, R. W.; Ghisalberti, E. L.; Jeffries, P. R. between 4.41 (i.e., pK. for (R)-3-hydrozybutyric acid) and 4.74 Phytochemistry 1983, 22

  19. I Actas Congreso. XXV años de estudios de género

    OpenAIRE

    Pinyana i Garí, M. Carme

    2004-01-01

    INDICE:Presentación,DORA SALES. De la academia a la sociedad. El papel de los estudios de las mujeres en la sociedad: tendiendo puentes entre la academia, las organizaciones de mujeres y las responsables políticas,CARMELA SANZ RUEDA. Los estudios de género crecieron con nosotras,MARÍA ELENA SIMÓN RODRÍGUEZ. Mecanismos para la integración de las prácticas de igualdad en las políticas generales, ROSA PERIS. Mujeres sabias del arte occidental,MARÍA TERESA BEGUIRISTAIN . Monólo...

  20. Hosea 6:6 and Identity Formation in Matthew | Viljoen | Acta ...

    African Journals Online (AJOL)

    Matthew uses Hos. 6:6 in two scenes of conflict between Jesus and the Pharisees. He defines the differences between Jesus and the Pharisees in terms of adherence to the Law with focus on the mercy that God desires. Matthew depicts Jesus as one who teaches and enacts Hos. 6:6 in continuity with the original prophetic ...

  1. Acta Theologica 2015: 2 209 J.H. Van Wyk, Teologie van die ...

    African Journals Online (AJOL)

    Die afgelope tyd het verskeie Suid-Afrikaanse teoloë bundels met versamelde werk of oorsigte van hul skryfwerk en lewe die lig laat sien. Mens dink hier aan die vyf-volume Collected Essays/Versamelde Opstelle van D.J. Smit;1 A Theological Odyssey: My life in writing en die outobiografie. I have come a long way van J.W. ...

  2. From the Acta Prize Lecture 2014: the periodontal-systemic connection seen from a microbiological standpoint.

    Science.gov (United States)

    Olsen, Ingar

    2015-01-01

    To give an overview of the periodontal-systemic connection seen from a microbiologist. Original research papers, review articles and workshop proceedings were consulted. Periodontal bacteria can cross epithelial cells, enter the circulation, invade endothelial cells, induce endothelial cell dysfunction and activate inflammatory and immune responses. Several studies support the association between periodontitis (PD) and cardiovascular disease. Severe PD involves a risk for development of type 2 diabetes. Maternal PD is moderately associated with adverse pregnancy outcome and pre-eclampsia. Dental plaque can contain respiratory pathogens able to promote chronic obstructive pulmonary disease and pneumonia. Periodontal bacterial DNA has been detected in synovial fluid of patients with rheumatoid arthritis. Minor evidence exists for associations between PD and chronic kidney disease, obesity, cancer, metabolic syndrome and cognitive impairment. Concerns can be raised as to the interpretation of some study results due to heterogeneity in definitions used for PD, too much weight upon in vitro studies with a few selected organisms and failing recognition that the majority of the periodontal microbiota is not yet cultivated. Periodontal bacteria may participate in extra-oral infections such as CVD, diabetes, APO, pre-eclampsia, COPD, pneumonia, RA, CKD, obesity, cancer, MetS and cognitive impairment. Most knowledge is based on associations which do not necessarily imply causality. Future studies should reach consensus on the definition of PD and systemic disease outcomes, recognize the full spectrum of the microbiota in PD and bacteremia, including not-yet-cultivated organisms and delineate the clinical significance of genetic strain variations and the role of periodontopathogenic vs gut organisms within atheromatous lesions. For demonstration of causality, large, long-term clinical studies should use well-defined criteria for PD and robust disease outcomes to elucidate the importance of PD intervention and prevention.

  3. Die geheim van die prediking: om mondig te word | Cilliers | Acta ...

    African Journals Online (AJOL)

    Hierdie artikel gaan uit van die oortuiging dat prediking 'n spraakgebeure is waarin die stem van die prediker - simbool van sy of haar persoonlikheid en spiritualiteit - 'n belangrike rol het om te speel. Die stem van die prediker mag nie misken word in die dinamiese struktuur van kommunikasie nie, en moet inteendeel op 'n ...

  4. Respek vir die liturgiese teks: J. Calvyn en J.S. Bach | Schulze | Acta ...

    African Journals Online (AJOL)

    Despite obvious differences in terms of historical and theological aspects between Calvin and Bach, both share a respect for the priority of the Biblical text in worship.The anomaly between Calvin's engagement in the versification of the Psalter and Bach's preference for the literal (rather than a versified) use of the Biblical ...

  5. Rethinking the demarcation of Malachi 2:17-3:5 | Snyman | Acta ...

    African Journals Online (AJOL)

    emarcating a unit remains important for the interpretation and understanding of the particular unit in a (Biblical) book. In the case of the book of Malachi, the majority of scholars adhere to the traditional demarcation of the fourth unit in the book of Malachi (2:17-3:5). Closer investigation reveals that the matter is not as settled ...

  6. Klaagliedere 3:42: vergifnis of nie-vergifnis? | O'Kennedy | Acta ...

    African Journals Online (AJOL)

    The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

  7. Gebed en Ou-Testamentiese teologie: research | O'Kennedy | Acta ...

    African Journals Online (AJOL)

    Prayer and old testament theology. Prayer should be an intrinsic part of theology because the way in which people understand the nature of God determines the nature and content of their prayers. This article poses the following question: In which way is prayer discussed in Old Testament theologies? This question is ...

  8. Maleagi 1:9 — 'n "Crux interpretum" | Snyman | Acta Theologica

    African Journals Online (AJOL)

    Malachi 1:9 presents the interpreter or exegete with unexpected difficulties. A number of these difficulties are treated in this article: problems pertaining to the translation of the text in Afrikaans, text-critical problems, the problem of the identity of the speaker(s); the question of whether the text should be interpreted as ironic or ...

  9. “Showing respect” in bible translation | van der Spuy | Acta Theologica

    African Journals Online (AJOL)

    This article focuses on the way respect is shown by using 2nd person personal pronouns in languages that distinguish between you plural (you all), you honorific (polite) and you singular (familiar) forms. It discusses the likely influence of the well known Russian Synodal Translation on other translations in the former Soviet ...

  10. The interpretation and translation of galatians 5:12 | Tolmie | Acta ...

    African Journals Online (AJOL)

    As is evident from commentaries on Galatians and from various English translations, scholars do not agree on the meaning, rhetorical labelling and translation of the wish expressed by Paul in Galatians 5:12 ( [Ofelon kai; ajpokovyontai oiJ ajnastatou` nte” uJma`”). In this article various interpretations of this verse are ...

  11. Philippians 4:10-23 from a rhetorical perspective | Snyman | Acta ...

    African Journals Online (AJOL)

    This article endeavours to analyse Phil. 4:10-23 from a different perspective to approaches which tend to force ancient rhetorical categories on the letter. On the basis of a text-centred approach, this part of the letter is divided into two sectons, namely 4:10-20 and 21-23. Paul's dominant rhetorical strategy in 4:10-20 could be

  12. A rhetorical analysis of Philippians 1:1-11 | Snyman | Acta Theologica

    African Journals Online (AJOL)

    The aim of this article is to analyse Philippians 1:1-11 from a rhetorical perspective that differs from the typical approach of researchers, who tend to force ancient rhetorical categories on a letter. The analysis is done in terms of what is called a “grounded theoretical approach”. This approach is briefly summarised, followed ...

  13. 1 Corinthians 1:18-31 from a rhetorical perspective | Snyman | Acta ...

    African Journals Online (AJOL)

    The approach followed in this article differs from that of researchers who force ancient rhetorical categories on a text or who regard only a few stylistic devices as rhetorical. The analysis is done in terms of what is called a “grounded theoretical approach.” This approach is briefly summarised, followed by a description of the ...

  14. Twentieth-century English Bible translations | Naudé | Acta Theologica

    African Journals Online (AJOL)

    The twentieth century has emerged as a major period of Bible translations and publications. The article explores both the cultural and social circumstances under which the English Bible translations of the twentieth century were produced and aspects relating to the translation process and reception. It offers insights into the ...

  15. IV Actas Congreso. Identidad de género vs Identidad sexual

    OpenAIRE

    Pinyana i Garí, M. Carme

    2008-01-01

    ÍNDICE Presentación. I. CONFERENCIAS Gender identities and bad habits,TERESA DE LAURETIS. Sobre las discontinuidades sexo-género-deseo en el arte contemporáneo,ERNEST ALCOBA. Transexualidad y feminismo: una relación incómoda,BEATRIZ GIMENO. Di-Versificaciones identitarias. Polifonías del Versus, MERI TORRAS Y BEGONYA SÁEZ. II. MESAS REDONDAS MESA 1 Las identidades sexuales en la ciencia y la salud La construcción de la identidad de género y la representación de ...

  16. III Actas Congreso. ¿Todas las mujeres podemos?: Género… y multiculturalidad

    OpenAIRE

    Pinyana i Garí, M. Carme

    2007-01-01

    ÍNDICE Presentación. I. CONFERENCIAS Life After Genocide, after the soul was shattered,JANJA BEC-NEUMANN. El impacto de los estudios de género en el desarrollo local,ESPERANZA BOSCH. La mujer inmigrante en España: análisis de la, situaciónSANÁA HARRAKI. La mujer como motor del desarrollo rural,TERESA LÓPEZ. Las mujeres en Internet ¿inmigrantes, exiliadas, turistas...?,REMEDIOS ZAFRA. . II. MESAS REDONDAS MESA 1 Mujeres ante el amor, el erotismo y el sexo en l...

  17. Tax Evasion and the Impact on Economic Growth Acta Universitatis Danubius. OEconomica

    Directory of Open Access Journals (Sweden)

    Shkendije Demalijaj Ukaj

    2014-12-01

    Full Text Available The level of taxation is very important for the development of current and future of a country and fiscal policy should always be considered as an important factor in the behavior of participants and their ability to tax evasion and informality. Government fiscal policies can trigger tax increase under pressure, especially in situations such as economic crisis, inflation, unemployment, instability, when the burden of this obligation grows, its effects are considered to take them to tax evasion and informality (Dragomir. et al. 2011. However, these reasons do not relate to all the great presence of this phenomenon in Kosovo, taking into account the recent economic crisis has not reflected in the economy of Kosovo and the Kosovo tax burden is among the lowest in the region, but leading cause of tax evasion and informality can be considered above the corruption of public administration officials including tax and customs officials, insufficient staff for his fighting, weak rule of law, as well as lower fiscal culture for paying taxes. For this reason the scope of this paper will be the theoretical treatment of the informal economy and tax evasion in view of tax avoidance, meaning, characteristics and their effects on the economy and possible recommendations on these viewpoints.

  18. Noticias médicas: acta de instalación del hospital militar de caucaya

    OpenAIRE

    Revista de la, Facultad de Medicina

    2011-01-01

    En Caucayá a seis de enero de mil novecientos treinta y tres, presentes el Coronel Comandante del Destacamento del Putumayo, don Roberto D. Rico; el Coronel Comandante del Batallón Huila, don Javier Tobar y Tobar; el Médico-Jefe de lá Sanidad del Destacamento, doctor Luis Patiño Camargo; varios jefes y oficiales del mismo, así como los oficiales de sanidad y los empleados militares al servicio del Destacamento, procedieron a inaugurar el hospital militar de Caucayá y a verificar la entrega de...

  19. Acta Oncologica Lecture. Gastrointestinal consequences of cancer treatment and the wider context: a bad gut feeling.

    Science.gov (United States)

    Muls, Ann Cecile

    2014-03-01

    The percentage of people living with a diagnosis of cancer is rising globally. Between 20% and 25% of people treated for cancer experience a consequence of cancer which has an adverse impact on the quality of their life. Gastrointestinal (GI) symptoms are the most common of all consequences of cancer treatment and have the greatest impact on daily activity. PATHOPHYSIOLOGY OF LONG-TERM BOWEL DAMAGE AFTER PELVIC RADIOTHERAPY: Long-term damage to the bowel after radiotherapy is mediated by ischaemic changes and fibrosis. Each fraction of radiotherapy causes a series of repetitive injuries to the intestinal tissue resulting in an altered healing process, which affects the integrity of the repair and changes the architecture of the bowel wall. THE NATURE OF GI SYMPTOMS THAT DEVELOP: Patient-reported outcome measures show that diarrhoea, urgency, increased bowel frequency, tenesmus and flatulence are the five most prevalent GI symptoms with a moderate or severe impact on patients' daily lives after treatment with pelvic radiotherapy. Many patients also experience fatigue, urinary problems and have sexual concerns. SYSTEMATIC ASSESSMENT AND MANAGEMENT: The complex nature of those symptoms warrants systematic assessment and management. The use of a tested algorithm can assist in achieving this. The most common contributing factors to ongoing bowel problems after pelvic radiotherapy are small intestinal bacterial overgrowth, bile acid malabsorption, pancreatic insufficiency, rectal bleeding and its impact on bone health. Symptom burden, socio-psychosocial impact, memory and cognitive function, fatigue, urinary problems and sexual concerns need to be taken into account when thinking about consequences of cancer treatment. As our understanding of consequences of cancer treatments continues to emerge and encompass a wide variety of specialties, a holistic, multifaceted and multidisciplinary approach is required to manage those consequences long-term.

  20. La dinámica participativa en las actas de reuniones del CONEI

    Directory of Open Access Journals (Sweden)

    Lilia Calderón Almerco

    2012-12-01

    Full Text Available The dynamism of participation in the minutes of the CONEI meetings This is a discussion about the results of a documentary research about the participative dynamics into the minutes of the CONEI (Consejo Educativo Institucional meetings of four public schools from Lima. The qualitative analysis of the minutes reveals that the participation characterizes for being formal, bureaucratic, unidirectional and conflicted; that is focused in the administrative and economic issues of the educational management. The discourse expresses an ideal vision about participation but negative about conflict. Also, the participation in the meeting is considered like being in the meeting, and the leadership of the principal and the teachers stands out, however, the students and parents are excluded or autoexcluded.

  1. Acta Theologica 2015: 2 207 M. Nel Identity-driven churches: Who ...

    African Journals Online (AJOL)

    in South Africa and in much of the remainder of the Christian world. Nel is clearly an evangelical who takes the Bible as his authoritative guide in all matters of doctrine and conduct. Yet he is cognisant of all the recent theological trends and is willing to learn from them and include those ideas he considers biblical and useful ...

  2. In search of the original text in Mark 9:38 | Hendriks | Acta Theologica

    African Journals Online (AJOL)

    The question remains which text appears to be the more original one. Several scholars – such as Vaganay, Duplacy, Amphoux, and others – in search of the original text of Mark – opt for a so called Western text, the main stream still prefers the Neutral text of Westcott and Hort. A text-critical analysis of Mark 9:38 may provide ...

  3. “Bond of love”: The action of the spirit | Williams | Acta Theologica

    African Journals Online (AJOL)

    The ancient idea, seen especially in Augustine, is that the main activity of the Spirit is that of providing relationship, as the “bond of love”; this provides a key concept which undergirds the work of the Spirit in creation, redemption, sanctification and empowering. It is hoped that increased understanding of the work of the Spirit ...

  4. Actas III Jornadas de Propiedad Intelectual. Los soportes en los que se recogen tangibles e intangibles.

    OpenAIRE

    Domenech Martínez, Gloria

    2013-01-01

    En estos tiempos tan convulsos que nos ha tocado vivir, es necesario proteger los derechos de propiedad intelectual para fomentar el crecimiento económico, la innovación y la creatividad. Las medidas destinadas a salvaguardar los derechos de propiedad intelectual (DPI) y a luchar contra la falsificación y la piratería en el mercado interior abarcan tanto el ámbito penal como el civil, sin olvidar el ámbito mercantil, jurisdicción especial en el campo civil. Sin relegar la pe...

  5. The spirituality of the Letter to the Galatians | Tolmie | Acta Theologica

    African Journals Online (AJOL)

    The spirituality of the Letter to the Galatians has not received much attention so far. Accordingly, this issue is addressed in this article. After a brief overview of two studies that have already been done in this regard, the focus of this investigation is formulated as the spirituality that comes to expression in the Letter to the ...

  6. Biblical spirituality: an “other” reading (allègoria) | Waaijman | Acta ...

    African Journals Online (AJOL)

    This article discusses the communicative dimension and dialogical dynamic of a text, in order to illuminate the relationship of Biblical Spirituality with the Bible. From a pragmatic perspective on the polar tension between author, text and reader, the article reflects on the action of the author-text on the reader, and the action of ...

  7. Psalm 51: Take not your Holy Spirit away from me | Maré | Acta ...

    African Journals Online (AJOL)

    Even a cursory reading of the New Testament makes one aware of numerous references to the Holy Spirit. The New Testament is thus normally the focus for studies on pneumatology. However, there are many references to jwr in the Old Testament of which 107 refer to God's activities in nature and in the lives of human ...

  8. El Greco's Representation of Mystical Ecstasy | Maré | Acta Theologica

    African Journals Online (AJOL)

    This article deals with one of El Greco's most original inventions, namely the gesture expressing mystical ecstasy in angelic and human figures. It is introduced with a brief explanation of figural representation in Renaissance painting which was achieved by applying the premises of rhetoric in a visual way, that is by the ...

  9. Acta Theologica 2013: 2 297 KRIEG, Robert A. 2013. Treasure in ...

    African Journals Online (AJOL)

    This apophatic bon mot, which recurs throughout Krieg's study, recaps well the theological profile and aspirations of the author. In Treasure in the. Field, he does not offer any ground-breaking insights, and yet by skilfully building upon the exegetical and theological Catholic tradition as well as contemporary psychological ...

  10. Digitalization of "Acta Stomatologica Croatica" Journal (1966;1 - 1999;33).

    Science.gov (United States)

    Borić, Vesna

    2014-09-01

    Modern documents, scientific articles and books are primarily issued in electronic form and their availability depends on the publisher's, or the document owner's, business ethics. The primary purpose of publishing a scientific article is to communicate with the scientific and professional community; therefore, the published article has to be available worldwide. The question is: Who really needs scientific papers from the 1960's? In cases of brilliant and bold visionaries, new concepts and scientific discoveries often come before their time; hence they have to be "reinvented" decades later. Besides, the scientists of today can enter the spiritual spheres of their professional ancestors and give respect to their legacy.
We have processed more than 1 200 articles published by 1999 and entered more than
6 000 names and surnames of authors.

  11. Digitalization of “Acta Stomatologica Croatica” Journal (1966;1 – 1999;33)

    Science.gov (United States)

    Borić, Vesna

    2014-01-01

    Summary Modern documents, scientific articles and books are primarily issued in electronic form and their availability depends on the publisher's, or the document owner's, business ethics. The primary purpose of publishing a scientific article is to communicate with the scientific and professional community; therefore, the published article has to be available worldwide. The question is: Who really needs scientific papers from the 1960's? In cases of brilliant and bold visionaries, new concepts and scientific discoveries often come before their time; hence they have to be "reinvented" decades later. Besides, the scientists of today can enter the spiritual spheres of their professional ancestors and give respect to their legacy.
We have processed more than 1 200 articles published by 1999 and entered more than
6 000 names and surnames of authors. PMID:27688363

  12. “One in christ”: Fedsem spiritualities of solidarity | Duncan | Acta ...

    African Journals Online (AJOL)

    The spiritual life of the seminary, manifested most clearly in its worship life, became its source of strength and sustained its mission and vision: to be and yet, to become “One in Christ”. This was conveyed by means of various forms of denominational and ecumenical solidarity as an expression of Christian love.

  13. Klaagliedere 3:42: vergifnis of nie-vergifnis? | O'Kennedy | Acta ...

    African Journals Online (AJOL)

    Lamentations 3 speaks about punishment, but not rejection or unwillingness to forgive. The worshipper in verse 42 confronts God with his real self: He is supposed to forgive. In the rest of chapter 3 we find reminders of God's forgiving heart: mercy and compassion (vv. 22, 32); faithfulness (v. 23); kindness (vv. 25, 26, 27); ...

  14. Noticias médicas: Acta de instalación del Hospital Militar de Caucaya

    Directory of Open Access Journals (Sweden)

    Facultad de Medicina Revista de la

    1933-04-01

    Full Text Available En Caucayá a seis de enero de mil novecientos treinta y tres, presentes el Coronel Comandante del Destacamento del Putumayo, don Roberto D. Rico; el Coronel Comandante del Batallón Huila, don Javier Tobar y Tobar; el Médico-Jefe de lá Sanidad del Destacamento, doctor Luis Patiño Camargo; varios jefes y oficiales del mismo, así como los oficiales de sanidad y los empleados militares al servicio del Destacamento, procedieron a inaugurar el hospital militar de Caucayá y a verificar la entrega de él a la dirección y administración de las Reverendas Hermanas de la Caridad de la Congregación de la Presentación, representadas en este acto por la Superiora del grupo de Caucayá, Reverenda Madre Cecilia María y por las Hermanas Ana Cecilia, Marta Rosa y Elisa María. Por acuerdo unánime se resolvió darle al Hospital el nombre de María Teresa, en honor de la señora María Teresa Londoño de Olaya, esposa del Excelentísimo señor doctor don Enrique Olaya Herrera, Presidente de la República, como homenaje a sus altas virtudes patricias y expresión de reconocimiento de la acción generosa por ella desarrollada en beneficio de la defensa nacional. El Coronel Rico, en su propio nombre y en el del  Destacamento del Putumayo, deja constancia de que la obra del Hospital se debe en gran parte a los esfuerzos del médico-jefe de la sanidad, doctor Luis Patiño Camargo, hombre sabio, modesto y abnegado, que ha puesto al servicio de la patria su ciencia de investigador, su infatigable y bondadosa actividad de facultativo y una desvelad vigilancia para proteger las vidas y aliviar 10.s sufrimientos de oficiales, tropas y civiles residentes en la actualidad en la región.

  15. The sixth seal in Revelation 6:12-17 | de Villiers | Acta Theologica

    African Journals Online (AJOL)

    In an introduction the nature and role of a close reading in Biblical Studies is briefly outlined. A second part analyses the form of the sixth seal and indicates what and how literary techniques were used to compose the text. These are then in turn investigated to explain the meaning and function of this seal within the ...

  16. Causes of death among the Caesars (27 BC-AD 476) | Retief | Acta ...

    African Journals Online (AJOL)

    The Roman Empire was ruled by 77 emperors between 27 BC and AD 476 (503 years); 18 (23,4%) of them held sway during the Early Empire (27 BC–AD 193, 220 years), and 59 (76,6%) during the Late Empire (193-476, 283 years). On the average emperors in the Early Empire ruled for a longer period (12,7 years as ...

  17. ACTA-EVER lecture 2007 - The retinal pigment epithelium: friend or foe?

    DEFF Research Database (Denmark)

    La Cour, Morten

    2008-01-01

    The retinal pigment epithelium (RPE) plays an important role in the physiology and pathophysiology of the vertebrate retina. The RPE absorbs fluid from the retinal extracellular space, via a proton-lactate-water co-transport mechanism located in the apical membrane of the epithelium. This mechanism...... proliferating RPE cells. By means of 5-bromo-2-deoxyuridine (BrdU) labelling, we studied the proliferation of RPE cells in the porcine eye after experimental posterior pole injury. Surprisingly, we found that only the peripheral RPE cells incorporated the BrdU label, indicating that central injury elicits...

  18. Erratum to "On guided wave propagation in fully clamped porous functionally graded nanoplates" [Acta Astronaut. 143 (2018) 380-390

    Science.gov (United States)

    Karami, Behrouz; Janghorban, Maziar; Li, Li

    2018-03-01

    We found a proofing error existing in the affiliation of the first and second authors of our article [1], We found a proofing error existing in the affiliation of the first and second authors of our article [1]. The correct affiliation should be "Department of Mechanical Engineering, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran".

  19. CGME´03 - Actas do Workshop "Computação Gráfica, Multimédia e Ensino"

    OpenAIRE

    Madeira, Joaquim; Sousa, António Augusto de

    2003-01-01

    CGME’03 - Workshop Computação Gráfica, Multimédia e Ensino, Porto, 8 de Outubro de 2003 Na sequência dos anteriores workshops Computação Gráfica no Ensino (CGE’91) e Computação Gráfica, Multimédia e Ensino (CGME’99), que ocorreram em Lisboa (IST) e Leiria (ESTG/IPL), e no âmbito da realização do 12º Encontro Português de Computação Gráfica (12.EPCG), teve lugar o segundo workshop Computação Gráfica, Multimédia e Ensino (CGME’03), nas instalações do Instituto Superior de Engenharia do...

  20. Comment on ;First experimental determination of the solubility constant of coffinite; [Geochim. Cosmochim. Acta 181 (2016) 36-53

    Science.gov (United States)

    Konings, R. J. M.; Plyasunov, A.

    2017-09-01

    Coffinite - USiO4 - is a key mineral for the modelling of the chemistry of uranium in silica-rich rocks. It is of particular interest for the modelling of the final storage of used nuclear fuel in deep geological respositories, as coffinite may be the solubility-controlling solid phase for uranium. This was extensively discussed by Szenknect et al. (2016) in a recent publication of the determination of the solubility constant of coffinite. The availability of pure USiO4 samples made it possible for the first time to accurately determine the solubility of this phase in aqueous solution (under-saturated conditions with respect to silica in 0.1 mol L-1 HCl). The study by Szenknect et al. (2016) is very extensive and in combination with the calorimetric determination of the enthalpy of formation of USiO4 from the same material batch (Guo et al., 2015), allows a re-assessment of the thermodynamic properties of this phase, revising the values from the OECD/NEA review in 1992 (Grenthe et al., 1992) that were based on estimated values for the Gibbs energy of formation of USiO4 by Brookins (1975) and the standard entropy by Langmuir (1978).

  1. Acta de la Jornada Técnica “Alternativas al lanzamiento en los desahucios hipotecarios” organizada por CESCO

    OpenAIRE

    Maja Lyczkowska, Karolina

    2012-01-01

    El día 12 de diciembre de 2012 se ha celebrado la Jornada Técnica Multicampus “Alternativas al lanzamiento en los desahucios hipotecarios”, organizada en Toledo por el Centro de Estudios de Consumo de la Universidad de Castilla-La Mancha (CESCO), que ha podido seguirse mediante videoconferencia en todos los campus de la UCLM. En ella, han participado jueces, abogados, y otros profesionales implicados, así como representantes de la Plataforma de Afectados por la Hipoteca. La gran ausente ha si...

  2. Evaluation of the implant-related restorative undergraduate programme at ACTA, the Netherlands. Part I: students' satisfaction

    NARCIS (Netherlands)

    Fijnheer, C.; Langhorst, F.R.; Wismeijer, D.

    2016-01-01

    Introduction: Due to the increasing use of dental implants, many future dentists will encounter implant-related procedures in general practice. Over the past decade, implant dentistry is more and more often included in undergraduate curricula. Very little is known about students' satisfaction

  3. Acta Medica Indonesiana - The Indonesian Journal of Internal Medicine 333 Supraclavicular Lymphnodes: Unusual Manifestation of Metastase Adenocarcinoma Colon

    Directory of Open Access Journals (Sweden)

    Harijono Achmad

    2015-12-01

    Full Text Available We report a patient with supraclavicular lymph node metastasis from an undetectable adenocarcinoma of the transverse colon, who presented with cough and was diagnosed with typhoid fever, bronchitis as well as liver metastasis. There were an abdominal fullness, weight loss, constipation, pencil-like stool with mucous and blood, low-grade fever, bone ache, and tea-color urine. The first colonoscopy revealed lymphocytic ileitis and microscopic findings also showed lymphocytic ileitis. Abdominal USG and CT revealed liver metastasis of unknown origin. Based on the clinical sign and symptoms, we suspected that colorectal carcinoma was the primary site. Then, the second colonoscopy was performed and it revealed a small polyp, which was followed with a biopsy and the result supported a well-differentiated colon adenocarcinoma. Similar result was also revealed by the histopathological evaluation. This is an unusual case of liver and supraclavicular lymph node metastasis arising from a small polyp adenocacinoma of the transverse colon. Key words: liver metastase, colorectal carcinoma, lymph node.

  4. I am the bread of life. Imagery in John 6:32-51 | van der Watt | Acta ...

    African Journals Online (AJOL)

    John 6 is one of the most discussed chapters in the Gospel according to John, because of the Eucharistic nature of the language in 6:51c-59. The complex nature of the metaphors and imagery used in these verses, as well as the richness and power of the ensuing communication, are often overlooked. This article explores ...

  5. Eco matters; In & Out

    Directory of Open Access Journals (Sweden)

    Editorial

    2016-11-01

    . Differentiation stage alters matrix control of stem cells. J Biomed Mater Res A. 2008; 85(1:145-56. Erratum in: J Biomed Mater Res A. 2008;87(1:282. Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell. 2006;126(4:677-89. Huang C, Dai J, Zhang XA. Environmental physical cues determine the lineage specification of mesenchymal stem cells. Biochim Biophys Acta. 2015;1850(6:1261-6. Lee J, Abdeen AA, Kilian KA. Rewiring mesenchymal stem cell lineage specification by switching the biophysical microenvironment. Sci Rep. 2014;4:5188. Evans ND, Minelli C, Gentleman E, LaPointe V, Patankar SN, Kallivretaki M, Chen X, Roberts CJ, Stevens MM. Substrate stiffness affects early differentiation events in embryonic stem cells. Eur Cell Mater. 2009;18:1-13; Jaramillo M, Singh SS, Velankar S, Kumta PN, Banerjee I. Inducing endoderm differentiation by modulating mechanical properties of soft substrates. J Tissue Eng Regen Med. 2015;9(1:1-12. Faraonio R, Pane F, Intrieri M, Russo T, Cimino F. In vitro acquired cellular senescence and aging-specific phenotype can be distinguished on the basis of specific mRNA expression. Cell Death Differ. 2002;9(8:862-4. Rubin H. Promise and problems in relating cellular senescence in vitro to aging in vivo. Arch Gerontol Geriatr. 2002;34(3:275-86. Brown PT, Handorf AM, Jeon WB, Li WJ. Stem cell-based tissue engineering approaches for musculoskeletal regeneration. Curr Pharm Des. 2013;19(19:3429-45. Minimal Manipulation of Human Cells, Tissues, and Cellular and Tissue-Based Products: Draft Guidance [Internet]. U.S. Food and Drug Administration [cited 2016 Nov 24]. Available from: http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/ Guidances/CellularandGeneTherapy/ucm427692.htm Gomathysankar S, Halim AS, Yaacob NS, Noor NM, Mohamed M. Compatibility of Porous Chitosan Scaffold with the Attachment and Proliferation of human Adipose-Derived Stem Cells In vitro. J Stem Cells Regen Med

  6. Corrigendum to "New constraints on kinetic isotope effects during CO2(aq) hydration and hydroxylation: Revisiting theoretical and experimental data" [Geochim. Cosmochim. Acta 214 (2017) 246-265

    Science.gov (United States)

    Sade, Ziv; Halevy, Itay

    2018-03-01

    The authors regret an error in the derivation of the link between KFFs and isotopic rate constants of CO2 hydration (Section 2.2). Considering the subset of isotopologues, C16O16O, C18O16O, H216O and H218O, there are four possible forward reactions: C16O16O + H216O → H2C16O16O16O,

  7. An analysis of U.S. Army Corps of Engineers documents supporting the channelization of the Rio Piedras. Acta Cientifica. 27(1-3).

    Science.gov (United States)

    Ariel Lugo; C.J. Nytch; M. Ramsey

    2013-01-01

    This paper has three objectives: 1) to provide a synopsis of the content of the reports, documents, data, and arguments used by the Corps to justify the channelization of the Rio Piedras; 2) to evaluate the accuracy of predictions and assumptions used by the Corps to reach conclusions that justify the channelization of the Rio Piedras; and 3) to make a case for the...

  8. Tetrodotoxin-induced conduction blockade is prolonged by hyaluronic acid with and without bupivacaine [Corrected from: Acta Anaesthesiol Scand 48 (1), 2004, 128-134

    NARCIS (Netherlands)

    Stevens, M. F.; Hoppe, M.; Holthusen, H.; Lipfert, P.

    2004-01-01

    BACKGROUND: In isolated nerves, tetrodotoxin (TTX) blocks nerve conduction longer than bupivacaine. In vivo, however, both substances block nerve conduction to an equal duration, presumably because the hydrophilic TTX binds only weakly to the perineural tissue. High molecular weight hyaluronic acid

  9. Simposio sobre Educacion de Ninas: Evidencias, Temas, Acciones. Actas de sesiones. (Symposium on Girls Education: Evidence, Issues, Actions. Proceedings). (Washington, DC, May 17-18, 2000).

    Science.gov (United States)

    Agency for International Development (IDCA), Washington, DC.

    This symposium highlighted core issues of controversy in girls' education and developed implications for policy and practice. Its evidence-based discussion forum encouraged dialogue, debate, and increased interaction and developed partnerships among academic institutions, nongovernmental organizations, multilateral development agencies, and other…

  10. Curriculum Perspectives: Challenges for the Future. Proceedings of a Binational Symnposium = Perspectivas curriculares: Retos para el futuro. Actas del simposio binacional (Austin, Texas, November 9-10, 1994).

    Science.gov (United States)

    Southwest Educational Development Lab., Austin, TX.

    This proceedings, in English and Spanish, describes the first U.S./Mexico Curriculum Symposium, held in Austin, Texas, in November 1994. The symposium grew out of an ongoing exchange between educators in the Republic of Mexico and the United States and was attended by over 200 teachers, administrators, staff from state and regional education…

  11. Reply to comment by Konings and Plyasunov on ;First experimental determination of the solubility constant of coffinite; [Geochim. Cosmochim. Acta 181 (2016) 36-53

    Science.gov (United States)

    Szenknect, S.; Dacheux, N.; Ewing, R. C.; Navrotsky, A.

    2017-09-01

    R.J.M. Konings and A. Plyasunov investigated the values of thermodynamic data determined by Szenknect et al. (2016) from solubility experiments performed using a synthetic sample of coffinite. Especially, they focused on the value of the standard molar entropy, which was derived from these solubility data and the calorimetric measurement of the standard molar enthalpy of formation of coffinite published by Guo et al. (2015). The two independent measurements were performed on the same synthetic sample prepared by Mesbah et al. (2015) and fully characterized using complementary techniques by the two teams. We thank Konings and Plyasunov for their comment and the relevant analysis of previously published work. As they concluded, we agree that new experimental data are required to solve the ;coffinite issue;. Here, we simply wish to clarify a few points regarding the questions arising from their analysis.

  12. [Criminal responsibility in schizophrenia with special attention to the mental state during the criminal act--a study based upon the activation-recurrence phenomenon].

    Science.gov (United States)

    Higashi, Takahiro

    2009-01-01

    In this article, psychiatric arguments regarding criminal responsibility in schizophrenia are reviewed, and it is pointed out that the arguments have been influenced by the theory of process psychosis. Moreover, two cases judged on the basis of the activation-recurrence phenomenon are exemplified, and fundamental issues are discussed. Investigating the mental state just before the crime helps when deliberating over criminal responsibility. A study of the activation-recurrence phenomenon, conducted by Shinkai and Miyasaka, contributes toward clarifying the recurrence of the micropsychotic state during the criminal act. Generally, schizophrenia is characterized by an alternation between the micropsychotic and basic normal states, and classified clinically into severe, moderate, and mild according to the level of susceptibility to the occurrence of the activation-recurrence phenomenon. Differentiating between the form and contents of the micropsychotic state is of marked importance in schizophrenia. In addition, identifying the form facilitates the distinction between behaviors while sane and those during schizophrenic episodes. Practically, the activating stimuli, which are likely to trigger the micropsychotic state, are applied in the interview to establish the psychiatric testimony based upon the activation-recurrence phenomenon. After the diagnosis of schizophrenia has been confirmed, the examinee is exposed to the stimuli possibly activating the micropsychotic state during the criminal act. Observing the recurrence of the micropsychotic state and its frequency enables estimation of the susceptibility to the occurrence of the activation-recurrence phenomenon and the mental state during the criminal act. Therefore, if a micropsychotic state during the criminal act can be confirmed, the inability to be held legally responsible is postulated. In contrast, if a micropsychotic state during the criminal act cannot be confirmed, the specialist giving the psychiatric testimony should conclude that the crime was most likely undertaken while sane, taking into account the objective circumstantial evidence and the suspect's coherent actions during the crime. Furthermore, in this article, the concept Trugerinnerung, which is a subjective abnormal experience confusing the present and past (a disorganization of memory) is revaluated, and the possibility of concluding that the criminal act was performed with a normal psychology is discussed.

  13. Estatística Ciência Interdisciplinar, Actas do XIV Congresso Anual da Sociedade Portuguesa de Estatística

    OpenAIRE

    Braumann, Carlos A.

    2007-01-01

    Book of invited conferences and accepted refereed papers submitted to the Procedings of the XIV Congresso Anual da Soceidade Portuguesa de Estatística (Covilhã, Portugal, 2006). The Editors were M. E. Ferrão, C. Nunes and C. A. Braumann.

  14. I Jornadas Anuales de la Sociedad Española de Medicina Legal y Forense: 3-4 de abril de 1987: libro de actas

    OpenAIRE

    Sociedad Española de Medicina Legal y Forense. Jornadas (1as : 1987 : Alicante)

    1987-01-01

    El volum conté 26 comunicacions elaborades pel seus autors de cara a la seva publicació en el present llibre d'actes. L'objectiu és donar a conèixer treballs d'investigadors de tot l'estat en l'àmbit de la Medicina Legal i Forense des d'un punt de vista multidisciplinar.

  15. Acta Medica Indonesiana - The Indonesian Journal of Internal Medicine 153 Malignant Pleural Effusion in Acute Myeloid Leukemia with Hepatitis B Virus Infection

    Directory of Open Access Journals (Sweden)

    C Suharti

    2016-05-01

    Full Text Available Pleural effusions can be the first presentation of a hematologic malignancy. The most common disorders with pleural effusion are Hodgkin and non-Hodgkin lymphoma with a frequency of 20 to 30%, especially if mediastinal involvement. Acute and chronic leukemia are rarely accompanied by pleural involvement. We describe a 46-year-old female with history of progressive dyspnoea. Physical examination was revealed massive left pleural effusion. Complete blood count revealed anemia, trombositopenia and normal leucocyte count. Viral serology test shown positive of HBsAg and total antiHBc. Chest X-ray revealed left pleural effusion. Pleural fluid cytology was myeloblast consistent with acute myeloid leukemia (AML. Bone marrow aspiration smear, bone marrow biopsy smear, and flow cytometry analysis were consistent with acute myeloid leukemia without maturation (AML M0-FAB classification. Key words: Acute myeloid leukemia, pleural effusion, infection.

  16. Tiny tweaks, big changes: An alternative strategy to empower ethical culture of human research in anesthesia (A Taiwan Acta Anesthesiologica Taiwanica-Ethics Review Task Force Report).

    Science.gov (United States)

    Luk, Hsiang-Ning; Ennever, John F; Day, Yuan-Ji; Wong, Chih-Shung; Sun, Wei-Zen

    2015-03-01

    For this guidance article, the Ethics Review Task Force (ERTF) of the Journal reviewed and discussed the ethics issues related to publication of human research in the field of anesthesia. ERTF first introduced international ethics principles and minimal requirements of reporting of ethics practices, followed by discussing the universal problems of publication ethics. ERTF then compared the accountability and methodology of several medical journals in assuring authors' ethics compliance. Using the Taiwan Institutional Review Board system as an example, ERTF expressed the importance of institutional review board registration and accreditation to assure human participant protection. ERTF presented four major human research misconducts in the field of anesthesia in recent years. ERTF finally proposed a flow-chart to guide journal peer reviewers and editors in ethics review during the editorial process in publishing. Examples of template languages applied in the Ethics statement section in the manuscript are expected to strengthen the ethics compliance of the authors and to set an ethical culture for all the stakeholders involved in human research. Copyright © 2015. Published by Elsevier B.V.

  17. Erratum to "Combustion oscillation study in a kerosene fueled rocket-based combined-cycle engine combustor" [Acta Astronaut. 129 (2016) 260-270

    Science.gov (United States)

    Huang, Zhi-Wei; He, Guo-Qiang; Qin, Fei; Xue, Rui; Wei, Xiang-Geng; Shi, Lei

    2017-03-01

    The publisher regrets that in the above article we found that Table 1 is present online, in the html version in ScienceDirect, but has been omitted in error from the final version of the PDF online and in the print version. The table can be found below:

  18. VI Actas Congreso. Miedos, culpas, violencias invisibles y su impacto en la vida de las mujeres: ¡A vueltas con el amor!

    OpenAIRE

    Gil Gómez, Alicia; Escrig Gil, Gemma; Forcada Martínez, Águeda

    2010-01-01

    ÍNDICE. Presentación,ESPERANZA BOSCH FIOL. Introducción poética, PACA GABALDÓN, CLAUDIA GRAVI Y Mª LUISA SAN JOSÉ. Justo el amor, MARÍA XOSÉ AGRA ROMERO. I. CONFERENCIAS El género en cuestión. Modelos imposibles y modelos perversos,DOLORES JULIANO CORREGIDO. La propia identidad y las relaciones de amor en la adolescencia, AURORA LEAL GARCÍA Feelings of fear and guilt among women in conflicts and wars.Miedos y culpas de mujeres en situaciones de conflictos y de guerra, RAN...

  19. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Science.gov (United States)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    ' work; point out any problems in organization or grammar; and suggest the steps necessary to complete the paper. They then go over the peer review form with the writer, referring any questions or disagreements to the instructor. It is most helpful if the instructor can also read and comment on the draft. General comments on the level of detail included and any problems with the reasoning come more appropriately from the instructor than from peers. The paper is then revised and handed in on the following week. The final draft is accompanied by a summary of revisions and copies of all peer reviews. Students are graded on peer reviews and summaries of revisions and cover letters, as well as on the final paper. Acknowledgments The molecular modeling workstations and associated software were purchased with funding from NSF, Instrumentation and Laboratory Improvement program, grant DUE-9350843 to AJW, with matching funds from Wellesley College. Some of the equipment for protein purification was funded by a grant from the Howard Hughes Medical Institute to Wellesley College. The authors are grateful to Paul Reisberg for helpful discussions in the early stages of this project and to Margaret Merritt for a critical review of the manuscript. Literature Cited 1. Blake, C. C. F.; Jonhson, L. N.; Mair, G. A.; North, A. C. T.; Phillips. D. C.; Sarma, V. R. Proc. Roy. Soc. London Ser. B 1967, 167, 378 - 388. 2. Hendrickson, H. S.; Giannini, J. L.; Bergstrom, J. P.; Johnson, S. N.; Leland, P. A. Biochem. Educ. 1995, 23, 14 - 17. 3. Miranker, A., Robinson, C. V.; Radford, S. E.; Aplin, R. T.; Dobson, C. M. Science 1993, 262, 896 - 900. 4. Turner, M. A.; Howell, P. L. Prot. Sci. 1995, 4, 442 - 449. 5. Radmacher, M.; Fritz, M.; Hansma, H. G.; Hansma, P. Science 1994, 265, 1577 - 1579. 6. Shugar, D. Biochim. Biophys. Acta 1952, 8, 302 - 309. 7. Bradford, M. M. Anal. Biochem. 1976, 72, 248 - 254. 8. Strang, R. H. C. In Practical Biochemistry for Colleges; Wood, E. J., Ed.; Pergamon: Oxford

  20. Peat and coconut fiber as biofilters for chromium adsorption from contaminated wastewaters.

    Science.gov (United States)

    Henryk, Kołoczek; Jarosław, Chwastowski; Witold, Żukowski

    2016-01-01

    Batch adsorption experiments were performed for the removal of chromium (III) and chromium (VI) ions from aqueous solutions using Canadian peat and coconut fiber. The Langmuir model was used to describe the adsorption isotherm. The maximum adsorption for peat reached 18.75 mg/g for Cr(III) and 8.02 mg/g for Cr(VI), whereas the value for fiber was slightly higher and reached 19.21 mg/g for Cr(III) and 9.54 mg/g for Cr(VI). Both chromium forms could be easily eluted from the materials. The adsorption of chromium forms to organic matter could be explained in terms of formation of donor-acceptor chemical covalent bound with hydroxyl groups as ligands and chromium as the central atom in the formed complex. The chromate-reducing activities were monitored with the use of electron paramagnetic resonance spectroscopy. The results showed that both adsorption and reduction occurred simultaneously and the maximum adsorption capacity of hexavalent chromium being equal to 95% for fiber and 92% for peat was obtained at pH 1.5. The reduction of Cr(VI) in wastewaters began immediately and disappeared after 20 h. Both materials contained yeast and fungi species which can be responsible for reduction of chromium compounds, due to their enzymatic activity (Chwastowski and Koloczek (Acta Biochim Pol 60: 829-834, 2013)). The reduction of Cr(VI) is a two-phase process, the first phase being rapid and based on chemical reaction and the second phase having biological features. After the recovery step, both types of organic materials can be used again for chromium adsorption without any loss in the metal uptake. Both of the materials could be used as biofilters in the wastewater treatment plants.

  1. Genetics Home Reference: Schindler disease

    Science.gov (United States)

    ... my area? Other Names for This Condition alpha-galactosidase B deficiency alpha-galNAc deficiency, Schindler type alpha- ... Klein A. Glycoprotein lysosomal storage disorders: alpha- and beta-mannosidosis, fucosidosis and alpha-N-acetylgalactosaminidase deficiency. Biochim ...

  2. The diverse roles of transverse filaments of synaptonemal complexes in meiosis

    NARCIS (Netherlands)

    Boer, de E.; Heyting, C.

    2006-01-01

    In most eukaryotes, homologous chromosomes (homologs) are closely apposed during the prophase of the first meiotic division by a ladderlike proteinaceous structure, the synaptonemal complex (SC) [Fawcett, J Biophys Biochem Cytol 2:403-406, 1956; Moses, J Biophys Biochem Cytol 2:215-218, 1956]. SCs

  3. Experimental evidence for two distinct deeply supercooled liquid states of water – Response to “Comment on ‘Water's second glass transition”’, by G.P. Johari, Thermochim. Acta (2015)

    Energy Technology Data Exchange (ETDEWEB)

    Stern, J.; Seidl, M. [Institute of Physical Chemistry, University of Innsbruck, 6020 Innsbruck (Austria); Gainaru, C. [Fakultät Physik, Technische Universität Dortmund, 44221 Dortmund (Germany); Fuentes-Landete, V.; Amann-Winkel, K.; Handle, P.H. [Institute of Physical Chemistry, University of Innsbruck, 6020 Innsbruck (Austria); Köster, K.W.; Nelson, H. [Fakultät Physik, Technische Universität Dortmund, 44221 Dortmund (Germany); Böhmer, R., E-mail: roland.bohmer@tu-dortmund.de [Fakultät Physik, Technische Universität Dortmund, 44221 Dortmund (Germany); Loerting, T., E-mail: thomas.loerting@uibk.ac.at [Institute of Physical Chemistry, University of Innsbruck, 6020 Innsbruck (Austria)

    2015-10-10

    Highlights: • Two samples of amorphous ices quench-recovered from 140 K to 0.07 GPa are compared. • Calorimetry, X-ray diffraction, dielectric spectroscopy and volumetry are employed. • The two samples are distinct and cannot both be termed “pressure-densified glassy water”. • One route of preparation leads to high- (HDA), and the other to low-density amorphous ice (LDA). • Two distinct glass transitions are observed and interpreted to indicate two liquid H{sub 2}O phases. - Abstract: Recently, our earlier data which led us to conclude that deeply supercooled water displays a second glass transition (Amann-Winkel et al., 2013) was reinterpreted (Johari, 2015). In particular, the increase in heat capacity observed for high-density amorphous ice (HDA) samples at 116 K was reinterpreted to indicate sub-T{sub g} features of low-density amorphous ice's (LDA's) glass transition. We reply to the criticism in detail and report an experiment triggered by the comment on our work. This experiment unequivocally confirms our original interpretation of the observations and reinforces the case for water's second glass transition, its polyamorphism, and the observation of two distinct ultraviscous states of water differing by about 25% in density.

  4. Western Hemisphere Conference on Persons with Disabilities. Conference Proceedings (Washington, D.C., March 14-18, 1993) = Conferencia Hemisferica Occidental sobre Personas con Discapacidades. Actas de la Conferencia. (Washington, D.C., 14 al 18 de Marzo de 1993).

    Science.gov (United States)

    Kelley, Jerry D., Ed.; And Others

    This document presents the proceedings of a conference which brought together delegates and First Ladies representing western hemisphere nations to address needs and issues affecting people with disabilities in the Americas. It presents the texts of two keynote addresses: "Small Triumphs, Big Victories: A Global View of Persons with…

  5. Corrigendum to ;On progress and rate of the peritectic reaction Fo + SiO2 → En in natural andesitic arc magmas; [Geochim. Cosmochim. Acta 185 (2016) 383-393

    Science.gov (United States)

    Zellmer, Georg F.; Sakamoto, Naoya; Matsuda, Nozomi; Iizuka, Yoshiyuki; Moebis, Anja; Yurimoto, Hisayoshi

    2018-01-01

    In the original article, an olivine dissolution rate of 3-6 × 10-11 m s-1 was quoted for the tephra we have studied. However, it was not considered that the crystal dissolves on all sides, rather than just on the one edge studied, so the diameter of the crystal will reduce by twice this rate, 9 (±3) × 10-11 m s-1.

  6. Coping with Social Change: Programs That Work. Proceedings of a Conference (Acapulco, Mexico, June 1989) = Como enfrentarse al cambio social: programas eficaces. Actas de uno Conferencia (Acapulco, Mexico, Junio de 1989).

    Science.gov (United States)

    Hoskins, Irene, Ed.

    Written in English and Spanish, this document contains the proceedings of the 14th International Congress of Gerontology on concerns about the impact of rapid social change on the well-being of older women and families in Latin American and the Caribbean and about effective programs that address the needs of the older populations. The first…

  7. Vārda brīvības un intelektuālā īpašuma aizsardzības līdzsvarošana ACTA

    OpenAIRE

    Bulzgis, Raivo

    2012-01-01

    Attīstoties intelektuālā īpašuma tiesībām un tā tiesiskajam regulējumam, tiek ierobežotas personu tiesības uz vārda brīvību. Ņemot vērā, ka tiek pieņemts jauns starptautiskais līgums šajā jomā, tad šī darba tēma ir aktuāla visā pasaulē. Darba mērķis ir noskaidrot, intelektuālā īpašuma un vārda brīvības robežas. Izvirzītā mērķa realizēšanai darba autors izvirzīja vairākus uzdevumus: izpētīt jēdzienus “vārda brīvība” un “intelektuālais īpašums”, analizēt šo jēdzienu robežas, kā arī iepazī...

  8. Actas del VI Coloquio Internacional Agón: Competencia y cooperación. De la Antigua Grecia a la actualidad : Homenaje a Ana María González de Tobía

    OpenAIRE

    Hamamé, Graciela N.; Schamun, María Cecilia

    2012-01-01

    El VI Coloquio Internacional ΑΓΩΝ: Competencia y Cooperación. De la Antigua Grecia a la actualidad, organizado por el Centro de Estudios Helénicos de la Facultad de Humanidades y Ciencias de la Educación de la Universidad Nacional de La Plata, se celebró en el Pasaje Dardo Rocha de la ciudad de La Plata durante los días 19, 20, 21 y 22 de junio de 2012. El encuentro estuvo dirigido a homenajear a la Dra. Ana María González de Tobia, gestora y organizadora de los cinco coloquios anteriores, di...

  9. Emprendimiento con perspectiva de género en la economía social. Actas del IX Congreso Estatal Isonomía sobre igualdad entre mujeres y hombres

    OpenAIRE

    Escrig Gil, Gemma; Sales Boix, Anna; Ortí Porcar, María José

    2013-01-01

    ÍNDICE. Presentación,M.ª JOSÉ SENENT VIDAL. I. CONFERENCIA. La desigual participación de hombres y mujeres en la economía social, M.ª ANTONIA RIBAS BONET . II. MESAS. MESA 1. Experiencias de mujeres en el ámbito de la economía social. Mujer, mercado laboral y economía social, CARMEN COMOS TOVAR . Sí al compromiso con las personas. Igualdad y conciliación, MARÍA ESTEVE ROYO. La realidad de las mujeres emprendedoras y empresarias de sociedades laborales,...

  10. Juan Ramón Jiménez-Nima Yushij, la frontera invisible: Actas del Seminario Internacional (Universidad Complutense de Madrid, 27-28 de abril de 2015)

    OpenAIRE

    Roca Sierra, Marcos (coord.)

    2016-01-01

    El Seminario Internacional Juan Ramón Jiménez - Nima Yushij ha sido organizado por la Universidad para los Mayores de la Universidad Complutense de Madrid, el Centro Cultural e Internacional Shahre Ketab de Teherán y la Consejería Cultural de la República Islámica de Irán en España. Se celebró en la Facultad de Filología de la UCM durante el mes de abril de 2015. Irán y España son dos potencias culturales que tienen mucho en común. No tenemos que olvidar que es el amor a la cultura, al fin...

  11. Corrigendum to "Pharmaceutical analysis in solids using front face fluorescence spectroscopy and multivariate calibration with matrix correction by piecewise direct standardization" [Spectrochim. Acta Part A: Mol. Biomol. Spectrosc. 103 (2013) 311-318

    Science.gov (United States)

    Alves, Julio Cesar L.; Poppi, Ronei J.

    2014-03-01

    The authors regret to inform that the tick labels of the ternary diagram axes in Fig. 1 were shown from 0% to 1.0% instead of 0% to 100%. The correct values of 0% to 100% are shown in the corrected Fig. 1 (see below). The right contents of the active ingredients in the sample sets shown in the diagram are now in agreement with the stated throughout the paper.

  12. Relationships between body mass index and short-circuit current in human duodenal and colonic mucosal biopsies. Osbak PS, Bindslev N, Hansen MB. Acta Physiol (Oxf). 2011 Jan;201(1):47-53

    DEFF Research Database (Denmark)

    Osbak, Philip Samuel; Bindslev, Niels; Berner-Hansen, Mark

    2011-01-01

    Aim: Retrospectively, to investigate the relationship between body mass index (BMI) and basal electrogenic transport as measured by short-circuit current (SCC) in human duodenal and colonic mucosal biopsies. Methods: The study included biopsies from mucosa of normal appearance in the sigmoid colon...... and >25 kg m)2). Statistical significance was assessed by the unpaired t-test or Wilcoxon rank-sum test. Correlation coefficients were calculated by Pearson product moment correlation. Results: In colonic biopsies, basal SCC (mean standard deviation) was significantly higher in 59 biopsies from 30...

  13. Actas de la 4th mesa redonda sobre investigacion en "Lenguas Extranjeras" en la Universidad Autonoma Metropolitana 1996. (Proceedings from the 4th Roundtable on Investigation in Foreign Languages in the Autonomous Metropolitan University 1996).

    Science.gov (United States)

    Zoreda, Margaret Lee, Comp.; Diop, Mamoudou Si, Comp.; Vivaldo Lima, Javier, Comp.

    The articles included in this volume were selected as exemplary papers from the conference in Mexico. The goal of the forum was to provide an opportunity for researchers from the three branches of the Universidad Autonoma Metropolitana (UAM) to meet and discuss research projects currently in progress at the university. The works presented here…

  14. Derechos Educacionales de los Padres: Una Explicacion de los Procedimientos de Seguridad para los Padres de Ninos con Discapacidades. Bajo la Clausula del Acta de Educacion para Individuos con Discapacidades (IDEA) y las Reglas para la Administracion del Acta de Educacion para Ninos Excepcionales (Educational Rights of Parents: An Explanation of Procedural Safeguards Available to Parents of Children with Disabilities. Under Provisions of the Individuals with Disabilities Education Act (IDEA) and the Rules for the Administration of the Exceptional Children's Educational Act [ECEA]).

    Science.gov (United States)

    Mountain Plains Regional Resource Center, Des Moines, IA.

    This pamphlet, in Spanish, describes Colorado parents' educational rights under federal and state special education rules and regulations. It addresses: (1) free appropriate public education and termination of services; (2) required prior notice to parents if there is a proposed change or refusal to change a child's special education program; (3)…

  15. Estimation in the partially observed stochastic Morris-Lecar neuronal model with particle filter and stochastic approximation methods

    DEFF Research Database (Denmark)

    Ditlevsen, Susanne; Samson, Adeline

    2014-01-01

    Parameter estimation in multidimensional diffusion models with only one coordinate observed is highly relevant in many biological applications, but a statistically difficult problem. In neuroscience, the membrane potential evolution in single neurons can be measured at high frequency, but biophys...

  16. Early Treatment of Shock and Injury

    Science.gov (United States)

    2013-10-01

    changes in arginine concentrations. This change appears to be caused by changes in the composition of the proteasome itself. As an example...Immunoproteasomes: TNF-α and Nitric Oxide Production are Regulated by Altered Composition of Proteasome-Active Sites. Cell Biochem Biophys 60:77-88...plastids of tangerine tomato fruits. Arch. Biochem. Biophys. 162:117-125, 1974. 30 13. Qureshi AA, Andrews AG, Qureshi N, and Porter JW. (1974) The

  17. Sciences & Nature: Editorial Policies

    African Journals Online (AJOL)

    CNF-CI), Botanique Pr AKOGBETO Martin (UAC-Bénin), Entomologie Pr AMANI N'. Georgres (UAA-CI), Biochime Dr BAGATÉ Karim (Foenape-France), Pharmacologie Pr BÉKRO Yves-Alains (UAA-CI) Chimie organique. Dr COULIBALY Lacina ...

  18. Development of Osseointegrated Implants for Soldier Amputees Following Orthopaedic Extremity Trauma

    Science.gov (United States)

    2008-08-01

    Jung (Leica) 2050 Microtome (Leica Microsystems Inc., Bannockburn, IL) with Accu-Edge® Low Profile Blades (Sakura Finetek U.S.A., Inc., Torrance, CA...119-30. 18. Matsuzaki K. Why and how are peptide-lipid interactions utilized for self- defense? Magainins and tachyplesins as archetypes . Biochim

  19. Genetics Home Reference: rhizomelic chondrodysplasia punctata

    Science.gov (United States)

    ... 1: report of mutations in 3 children from India. J Appl Genet. 2010;51(1):107-10. doi: 10.1007/BF03195717. Citation on PubMed Steinberg SJ, Dodt G, Raymond GV, Braverman NE, Moser AB, Moser HW. Peroxisome biogenesis disorders. Biochim ...

  20. DOI: 10.4025/actascibiolsci.v33i3.8011 Acta Scientiarum. Biological Sciences Maringá, v. 33, n. 3, p. 239-246, 2011 Acute inflammatory response in Nile tilapia fed probiotic Lactobacillus plantarum in the diet = Resposta inflamatória aguda em tilápia do Nilo alimentada com probiótico, Lactobacillus plantarum na dieta

    Directory of Open Access Journals (Sweden)

    Geovana Dotta

    2011-07-01

    Full Text Available The present study evaluated the acute inflammatory response induced bycarrageenin (500 £gg injected in the swim bladder of Nile tilapia, after fed or not probiotic supplemented diet. Fifty four fish were distributed in six treatments and three replicates: Group A: Fish fed unsupplemented diet: 0.5 mL saline-injected fish; fish injected with 500 £gg carrageenin diluted in 0.5 mL saline; Non-injected. Group B: Fish fed probiotic supplemented diet: saline-injected fish; carrageenin-injected fish; Non-injected. Fifteen days after feeding the fish were injected with carrageenin or saline. After six hours, inflammatory exudate was collected, as well as the blood for hematocrit, red blood cell (RBC and white blood cell (WBC counts, differential count of leucocytes and phagocytic activity in the blood. Supplementation with probiotic did not influence the RBC, hematocrit and the numbers of lymphocytes and basophils in the blood. The number of neutrophils was significantly higher in supplemented fish injected with carrageenin. Glucose concentration in supplemented and non-injected fish was higher than that observed in the saline injected ones. Probiotic potentialized the migration of cells to the inflammatory focus in the animals injected with the carrageenin irritant. In fish injected with saline and carrageenin occurred the greatest phagocytic activity in the blood in relation to those treatments.Este trabalho avaliou a resposta inflamatoria aguda induzida por injecao de carragenina (500 ƒÝg na bexiga natatoria de tilapia do Nilo suplementada ou nao com probiotico na racao. Cinquenta e quatro animais foram distribuidos em seis tratamentos com tres repeticoes: Grupo A: peixes alimentados com racao naosuplementada: Controle (injecao de 0,5 mL de solucao salina esteril; Carragenina (injecao de500 £gg de carragenina; Nao-injetada. Grupo B: peixes alimentados com racao suplementada com probiotico: Controle; Carragenina; Nao-injetada. Apos 15 dias de alimentacao foi injetado carragenina ou salina. Apos 6h, realizou-se a coleta de exsudato e sangue para determinacao do hematocrito, contagens totais de eritrocitos, leucocitos, contagem diferencial de leucocitos e atividade fagocitaria no sangue. A suplementacao com probiotico na racao nao influenciou o numero total de eritrocitos, o hematocrito e os numeros de linfocitos e basofilos no sangue dos animais. O numero de neutrofilos foi maior nos peixes suplementados com probiotico einjetados com carragenina. A glicose nos peixes suplementados com probiotico nao-injetados foi maior do que nos injetados com salina. A suplementacao com probiotico potencializou a migracao de celulas para o foco inflamatorio nos injetados com o flogogeno carragenina. Empeixes injetados com salina e carragenina, ocorreu maior atividade fagocitaria no sangue em relacao aos demais tratamentos.

  1. ACTAS AEL 7. VI Seminario de Judía. Seminario sobre la eficiencia del sistema simbiótico Phaseolus-Rhizobium y su incidencia en la genética y mejora (Proyecto CSIC i-COOP 2016SU0004)

    OpenAIRE

    Ron Pedreira, Antonio Miguel de; Clemente, Alfonso

    2016-01-01

    Contiene la contribución de los participantes en el VI Seminario de Judía y en el Seminario sobre la eficiencia del sistema simbiótico Phaseolus-Rhizobium (dentro del proyecto del CSIC i-COOP 2016SU0004) celebrado en la Estación Experimental del Zaidín (CSIC, Granada) los días 25 y 26 de Octubre de 2016. A la celebración de estos Seminarios contribuyeron la Asociación Española de leguminosas (AEL), la Sociedad Española de Fijación de Nitrógeno (SEFIN), la Estación Experimental del Zaidín (EEZ...

  2. Guia del Proceso del IFSP de Colorado: Conexiones para la Ninez Temprana, Iniciativa Infantil de Colorado Parte C del Acta de Educacion para Individuos con Desabilidades (Colorado Guidelines for the IFSP Process: Early Childhood Connections, Colorado's Infant/Toddler Initiative for Part C of the Individuals with Disabilities Education Act).

    Science.gov (United States)

    Miller, Jerri; Petersen, Sandy

    This booklet for Spanish-speaking parents of young children with disabilities describes Colorado's Individualized Family Service Plan (IFSP) process. It explains guidelines, shares family stories and reflections for families and care providers, and the describes the values that drive the IFSP process in Colorado. Information is provided on…

  3. People’s Republic of China Scientific Abstracts No. 179

    Science.gov (United States)

    1977-11-08

    No 2, April 1977 7 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 2, June 1977 22 I-CH’UAN HSUEH-PAO [ACTA GENETICA SINICA] No 1...of light energy. How luminescent molecules can store such great energy has not yet been ascertained. 11310 CSÖ: J*009 21 ACTA BOTANICA SINICA...and Peking Institute of Botany, Academia Sinica TITLE: "Studies on Maize Anther Culture" SOURCE: Peking CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA

  4. Změny využití krajiny u jihomoravských vodních nádrží

    Czech Academy of Sciences Publication Activity Database

    Havlíček, M.; Halas, Petr; Lacina, Jan; Mlejnková, H.

    2014-01-01

    Roč. 2014, č. 108 (2014), s. 25-35 ISSN 1805-921X Institutional support: RVO:68145535 Keywords : land use * water reservoir * vegetation Subject RIV: DE - Earth Magnetism, Geodesy, Geography http://www.vukoz.cz/acta/dokumenty/acta_108/Acta-108_komplet-cz.pdf

  5. Kinetics in Gas Mixtures for Problem of Plasma Assisted Combustion

    Science.gov (United States)

    2010-05-01

    Pergamon Press, 1958.) [7] Dubovitsky F 1935 Acta Physicochim. URSS 2 361 [8] Nalbandjan A 1934 Acta Physicochim. URSS 1 305 [9] Gorchakov G, Lavrov F...1934 Influence of electric discharge on the region of spon- taneous ignition in the mixture 2H2–O2 Acta Physicochim. URSS 1 139—44 [10] MacLeana H L

  6. China Report, Agriculture

    Science.gov (United States)

    1985-12-12

    ABSTRACTS GENETICS YICHUAN XUEBAO [ACTA GENETICA SINICA], No 3, 1985 79 YICHUAN [HEREDITAS], No 4, Jul 85" 80 ZHIWU XUEBAO [ACTA BOTANICA ...VIABLE EMBRYO SACS AND THEIR PROTOPLASTS OF NICOTIANA TABACOM Beijing ZHIWU XUEBAO [ACTA BOTANICA SINICA] in Chinese No 4, 1985 pp 337-344 [English

  7. Regulation of Chemokine Expression by Lipopolysaccharide In Vitro and In Vivo

    Science.gov (United States)

    2002-06-10

    McMurray, D. Smith, J. Sims, 194 T. Bird , and L. O’Neil. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature...HuMig: a new human member of the chemokine family of cytokines. Biochem. Biophys. Res. Commun. 192:223. 128. Cole, K., C. Strick, T. Paradis , K

  8. Regulatory single nucleotide polymorphisms at the beginning of ...

    Indian Academy of Sciences (India)

    2015-11-28

    Nov 28, 2015 ... 1988 Beta-thalassemia due to a T–A mutation within the. TATA box. Biochem. Biophys. Res. Commun. 153 741–747. Fleming JD, Pavesi G, Benatti P, Imbriano C, Mantovani R and. Struhl K 2013 NF-Y coassociates with FOS at promoters, en- hancers, repetitive elements, and inactive chromatin regions, ...

  9. Influence of dietary supplementation on biotransformation of locust ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-03-20

    Mar 20, 2009 ... A modified ninhydrin Colorimetric analysis for amino acids. Arch. Biochem. Biophys. 67: 10-15. Sharma JL, Caralli S (2002). A dictionary of food and nutrition CBS. Publishers and Distributors. New delhi – 2, India pp. 518-521. Snedecor GW (1956). Statistical Methods 5th edn Iowa State college. Press.

  10. Fulltext PDF

    Indian Academy of Sciences (India)

    in human and animal tissues (fat). In humans, the half- life of TCDD is estimated to be 7–10 ... account dioxin accumulation in fat tissue and the important role of pork in human nutrition as well as the fact that ...... carbon receptor polymorphisms that result in loss of CYP1A1 induction. Biochem. Biophys. Res. Commun. 288 ...

  11. RESEARCH ARTICLE

    Indian Academy of Sciences (India)

    Navya

    solubility and chemical stability, TCDD easily accumulates in human and animal tissues (fat). In humans, the half-life of ... fat tissue and the important role of pork in human nutrition as well as the fact that AhR and. ARNT genes in the pig are ..... polymorphisms that result in loss of CYP1A1 induction. Biochem. Biophys. Res.

  12. Internal motions in proteins: A combined neutron scattering and ...

    Indian Academy of Sciences (India)

    This smooth, 'depth-dependent' model of dynamics may have important consequences for protein function. It may allow local reorganisation of the structure for efficient ligand binding without affecting the internal stability. References. [1] J A Mc Cammon, Rep. Prog. Phys. 47, 1 (1984). [2] J C Smith, Quart. Rev. Biophys.

  13. Pattern of change in histone 3 lysine 9 acetylation and histone ...

    Indian Academy of Sciences (India)

    2014-08-11

    Aug 11, 2014 ... Kim Y. S., Kim M. J., Koo T. H., Kim J. D., Koun S., Ham H. J. et al. 2012 Histone deacetylase is required for the activation of Wnt/β- catenin signaling crucial for heart valve formation in zebrafish embryos. Biochem. Biophys. Res. Commun. 423, 140–146. Kratz A., Arner E., Saito R., Kubosaki A., Kawai J., ...

  14. Single-nucleotide variations associated with Mycobacterium ...

    Indian Academy of Sciences (India)

    surveillance, planning, financing (Geneva: World Health. Organization). Wu X, Jornvall H, Berndt K and Oppermann U 2004 Codon optimization reveals critical factors for high level expression of two rare codon genes in Escherichia coli: RNA stability and secondary structure but not tRNA abundance; Biochem. Biophys. Res ...

  15. Enhanced Oxidative Bioremediation of cis-dichloroethene (cis-DCE) and Vinyl Chloride (VC) using Electron Shuttles

    Science.gov (United States)

    2009-07-01

    Biophys. Res. Commun. 261:562-566. 5 Madigan M. T., Martinko J. M. and Parker J. (2000) Table A1.2. In: Brock Biology of Microorganisms , App. A-4...1998. Quinone Moieties Act as Electron Acceptors in the Reduction of Humic Substances by Humics-Reducing Microorganisms . Environ. Sci. Technol. 32

  16. Measurement of soil-gas radon in some areas of northern Rajasthan ...

    Indian Academy of Sciences (India)

    The health hazards of the radioactive gas radon on general public are well known. In order to .... tant benefit of solid state devices is ruggedness. Another ..... Sinai, Egypt; Phys. Chem. Biophys. 3(4) 1–6. Kristiansson K and Malmqvist L 1982 Evidence for non- diffusive transport of. 222. Rn in the ground and a new physical ...

  17. Fulltext PDF

    Indian Academy of Sciences (India)

    2012-01-24

    Jan 24, 2012 ... Jackson JH, George R and Herring PA 2000 Vectors of Shannon information from Fourier signals characterizing base periodicity in genes and genomes. Biochem. Biophys. Res. Commun. 268. 289–292. Jurka J, Kapitonov VV, Pavlicek A, Klonowski P, Kohany O and. Walichiewicz J 2005 Repbase Update, ...

  18. People’s Republic of China Scientific Abstracts No. 180

    Science.gov (United States)

    1977-11-25

    translations of these articles. CONTENTS PAGE CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 1, March 1977 1 K’UN-CH’UNG HSUEH-PAO [ACTA ENTOMOLOGICA...March 1977. 28 TUNG-WU HSUEH-PAO [ACTA ZOOLOGICA SINICA] No 2, June.1977 41 a - [III - CC - 70 S § T] ACTA BOTANICA SINICA AUTHOR...HSUEH-PAO [ACTA BOTANICA SINICA] in Chinese Vol 19 No 1, Mar 77 pp 7-10 TEXT OF ENGLISH ABSTRACT: In 1964, we some young teachers and students in

  19. Creativity and Democratic Governance. Adult Learning: A Strategic Choice. Proceedings of the ICAE World Assembly (6th, Ocho Rios, Jamaica, August 9-12, 2001) = Creativite et Gouvernance Democratique. L'apprentissage des Adultes: Un Choix Strategique. Actes de la Assemblee Mondiale du CIEA (6th, Ocho Rios, Jamaique, 9 au 12 aout 2001) = Creatividad y Gobernabilidad Democratica. Educacion de Adultos: Una Eleccion Estrategica. Actas de la Asamblea Mundial del ICAE (6th, Ocho Rios, Jamaica, Agosto 9-12, 2001).

    Science.gov (United States)

    Dobson, Stephan, Ed.

    This document contains information from and about a world assembly on creativity and democratic governance in adult learning that was held by the International Council for Adult Education (ICAE) and its partner organizations in the Caribbean. The proceedings begin with English, French, and Spanish translations of the address…

  20. Nanosecond Pulsed Electric Field Induced Dose Dependent Phosphatidylinositol-4,5-bisphosphate Signaling and Intracellular Electro-sensitization

    Science.gov (United States)

    2017-01-05

    of varying duration (10, 30, 60, 200, 400, or 600 ns) using a custom microelectrode comprised of a pair of cylin- drical 125 μm tungsten wires placed...2009) 92–99. [18] Z.A. Levine, P.T. Vernier, Life cycle of an electropore: field-dependent and field-inde- pendent steps in pore creation and... annihilation , J. Membr. Biol. 236 (1) (2010) 27–36. [19] B. Hille, E.J. Dickson, M. Kruse, O. Vivas, B.-C. Suh, Phosphoinositides regulate ion channels, Biochim

  1. JPRS Report, Science & Technology. China: Stealth/Counter-Stealth Research.

    Science.gov (United States)

    1992-11-19

    Frequency-Selective Surfaces 92FE0801F Beijing DIANZIXUEBAO [ACTA ELECTRONICA SINICA] in Chinese Vol 20 No 6, Jun 92 pp 85-88 [Article by Shen...microwave devices and electromag- netic scattering. Motion Compensation Method in ISAR Imaging 92FE0801A Beijing DIANZIXUEBAO [ACTA ELECTRONICA ...Chinese Society of Electronics and an editor of DIANZI XUEBAO [ACTA ELECTRONICA SINICA]. Deng Wenbiao Born in February 1961, he graduated from the

  2. Hybné síly dlouhodobých proměn industrializované krajiny (Případová studie Hrušov)

    Czech Academy of Sciences Publication Activity Database

    Martinát, Stanislav; Dvořák, Petr; Klusáček, Petr; Kunc, Josef; Havlíček, M.

    2014-01-01

    Roč. 106, č. 106 (2014), s. 35-44 ISSN 1805-921X R&D Projects: GA MŠk EE2.3.20.0025 Institutional support: RVO:68145535 Keywords : Hrušov * Ostrava * industrial landscape * deindustrialisation * brownfields Subject RIV: DE - Earth Magnetism, Geodesy, Geography http://www.vukoz.cz/acta/dokumenty/acta_106/Acta-106_komplet-cz.pdf

  3. Endogenous Protection Derived from Activin A/Smads Transduction Loop Stimulated via Ischemic Injury in PC12 Cells

    OpenAIRE

    Mang, Jing; Mei, Chun-Li; Wang, Jiao-Qi; Li, Zong-Shu; Chu, Ting-Ting; He, Jin-Ting; Xu, Zhong-Xin

    2013-01-01

    Activin A (ActA), a member of transforming growth factor-beta (TGF-b) super- family, affects many cellular processes, including ischemic stroke. Though the neuroprotective effects of exogenous ActA on oxygen-glucose deprivation (OGD) injury have already been reported by us, the endogenous role of ActA remains poorly understood. To further define the role and mechanism of endogenous ActA and its signaling in response to acute ischemic damage, we used an OGD model in PC12 cells to simulate isch...

  4. Looduslikult kestliku ja inimlähedase elu otsingud / Martin Mölder

    Index Scriptorium Estoniae

    Mölder, Martin, 1983-

    2011-01-01

    Raamatuarvustus: Ökokogukonnad retoorikas ja praktikas : elustiilide uurimused / toimetanud Airi-Alina Allaste. Tallinn : Tallinna Ülikooli Kirjastus, 2011. (Acta Universitatis Tallinnensis. Socialia)

  5. Reappraisal of disparities between osmolality estimates by freezing point depression and vapor pressure deficit methods.

    Science.gov (United States)

    Winzor, Donald J

    2004-02-15

    As a response to recent expression of concern about possible unreliability of vapor pressure deficit measurements (K. Kiyosawa, Biophys. Chem. 104 (2003) 171-188), the results of published studies on the temperature dependence of the osmotic pressure of aqueous polyethylene glycol solutions are shown to account for the observed discrepancies between osmolality estimates obtained by freezing point depression and vapor pressure deficit osmometry--the cause of the concern.

  6. Early Treatment in Shock

    Science.gov (United States)

    2011-06-01

    10600. 16. Qureshi N, Qureshi AA. (1993) Tocotrienols, novel hypocholesterolemic agents with antioxidant properties . In: Packer L, Fucks J, (eds...identification of novel tocotrienols from rice bran with hypocholesterolemic, antioxidant , and antitumor properties . J. Agri. & Food Chem. 48: 3130-3140...a soluble enzyme obtained from the plastids of tangerine tomato fruits . Arch. Biochem. Biophys. 162:117-125, 1974. 12. Qureshi AA, Andrews AG

  7. Transcriptomic Analysis of the Effects of a Fish Oil Enriched Diet on Murine Brains

    Science.gov (United States)

    2014-03-14

    OMICS 11: 143–151. 51. Clark WF, Parbtani A (1994) Omega-3 fatty acid supplementation in clinical and experimental lupus nephritis . Am J Kidney Dis 23...1994) Decreased pro-inflammatory cytokines and increased antioxidant enzyme gene expression by omega-3 lipids in murine lupus nephritis . Biochem Biophys...dietary source of n-3 PUFA have been extensively studied as dietary supplements suggesting beneficial effects for the treatment of inflammation [4– 6

  8. Anti-NGF Local Therapy for Autonomic Dysreflexia in Spinal Cord Injury

    Science.gov (United States)

    2014-12-01

    domain with a large extracellular portion similar to dipeptidyl peptidase (DPP6/10) (Jerng et al., 2004; Nadal et al., 2003; Ren et al., 2005...S A 2002;99:1035–40. Jerng HH, Qian Y, Pfaffinger PJ. Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10). Biophys J...Hayashi Y, Yoshimura N, Takimoto K. Transmembrane interaction mediates complex formation between peptidase homologues and Kv4 channels. Mol Cell

  9. Carnitine prevents the early mitochondrial damage induced by methylglyoxal bis(guanylhydrazone) in L1210 leukaemia cells.

    OpenAIRE

    Nikula, P; Ruohola, H; Alhonen-Hongisto, L; Jänne, J

    1985-01-01

    We previously found that the anti-cancer drug methylglyoxal bis(guanylhydrazone) (mitoguazone) depresses carnitine-dependent oxidation of long-chain fatty acids in cultured mouse leukaemia cells [Nikula, Alhonen-Hongisto, Seppänen & Jänne (1984) Biochem. Biophys. Res. Commun. 120, 9-14]. We have now investigated whether carnitine also influences the development of the well-known mitochondrial damage produced by the drug in L1210 leukaemia cells. Palmitate oxidation was distinctly inhibited in...

  10. Acetylcholine Receptors in Model Membranes: Structure/Function Correlates.

    Science.gov (United States)

    1985-12-01

    reconstituted into phospholipid vesicles. The reconstituted sodium channel exhibited in the vesicle sodium transport was activated by batrachotoxin (BXT...kinetics of purified sodium channels modified by batrachotoxin . J. Gen. Physiol. 88:1-23. 20. Hartshorne, R.P., Kelier, B.U., Talvenheimo, J.A...gating kinetics of purified sodium channels modified by batrachotoxin in planar lipid bilayers. Biophys. J. 47:Abst. 439a. 9. Montal, M., HJartshorne

  11. IS THERE A LACTATION ANOESTRUS IN THE SHEEP?

    African Journals Online (AJOL)

    MALLAMPATI, R.S., POPE, A.L. & CASTDA, L.8., 1971. J . A n i m . S c i . 3 2 , 6 7 3 . MAULEON, P. & DAUZIER, L., 1965. Annls Biol. anim. Biocirirn. Biophys. 5, l3l. N.R.C., 1968. Nutrient Requirements of Sheep. Publ. 1963, Nat. Acad. Sci., Nat. Res. Counc., Washing- ton, D.C.. RESTALL, B.J., 1971. Proc. Aust. Soc. Reprod.

  12. Cross-Linking in Collagen by Nonenzymatic Glycation Increases the Matrix Stiffness in Rabbit Achilles Tendon

    OpenAIRE

    Reddy, G. Kesava

    2004-01-01

    Nonenzymatic glycation of connective tissue matrix proteins is a major contributor to the pathology of diabetes and aging. Previously the author and colleagues have shown that nonenzymatic glycation significantly enhances the matrix stability in the Achilles tendon (Reddy et al., 2002, Arch. Biochem. Biophys., 399, 174–180). The present study was designed to gain further insight into glycation-induced collagen cross-linking and its relationship to matrix stiffness in the rabbit Achilles tendo...

  13. Biomarker Discovery and Mechanistic Studies of Prostate Cancer Using Targeted Proteomic Approaches

    Science.gov (United States)

    2012-07-01

    epithelium of benign pathology) was generously provided by Dr. Simon W. Hayward (Department of Urological Surgery, Vanderbilt University Medical Center...Western blotting. Stable tansfectants were cloned under Geneticin selection (Invitrogen) (300µg/ml), the generated clones were maintained in RPMI 1640...Kuno N, Muramatsu H, et al. Abnormalities of sensory and memory functions in mice lacking Bsg gene. Biochem Biophys Res Commun 1997; 236:733-7. 9

  14. Detoxification of Mycotoxins and Other Compounds of Military Interest

    Science.gov (United States)

    1987-01-14

    CLASSIFICATION lb. RESTRICTIVdE MARKINGS Unc lassi fied 2&. SECURITY CLASSIFICATION AuTmORITY 3. OISThJ5UTION IAVAILAWPTY OF REPORT...Introduction- Experiments were performed to probe for GSH conjugate formation with T-2 toxin and the excretion of this conjugate and/or its metabolites...Ed.), 7:101-188. Academic Press, Now York. 8. Anderson, M.E., Powrie, F., Puri, R.N., and Hoister, A. (1985), Arch. Biochem. Biophys., 239:538-548

  15. Peptides for Specific Intracellular Delivery and Targeting of Nanoparticles: Implications for Developing Nanoparticle-Mediated Drug Delivery

    Science.gov (United States)

    2010-01-01

    efficiently internalized by cells when present in the surrounding tissue culture media [50,51]. Subsequent studies to determine the domain responsible for...therapeutic heat shock protein, they expressed and purified a recombinant Pep-1–HSP-27 fusion protein in bacteria. When added to the tissue culture media of...cloning and genomic organization of a novel receptor from Drosophila   melanogaster structurally related to mammalian galanin receptors. Biochem. Biophys

  16. Molecular Interactions in the Replication of Mouse Hepatitis Virus

    Science.gov (United States)

    1987-05-08

    separated by size exclusion HPLC followed by SDS- hydroxyapatite HPLC (Sturman et g., 1985). One, termed ජA", was acylated with palmitic acid, whereas...reagent. J. Biol. Chem. 193: 265-275. Luft, J.H. 1961. Improvements in epoxy resin embedding methods. J. Biophys. Biochem. Cytol. 9: 409-414...17: 208-212. Ricard, C.S. and Sturman, L.S. 1985. Isolation of the subunits of the coronavirus envelope glycoprotein E2 by hydroxyapatite high

  17. Human Pregnancy-Specific Glycoproteins Function as Immunomodulators In Vitro by Inducing Secretion of IL-10 and IL-6 in Human Monocytes

    Science.gov (United States)

    2000-02-29

    antigen gene family members in submandibular salivary gland : demonstration ofpregnancy-specific glycoproteins by cDNA cloning. Biochem Biophys Res...presence ofCEA in serum has been used diagnostically to monitor progression ofpatients with colon cancer (Shively and Beatty, 1985). CEA transcripts...levels ofserum PSGs have also been associated with non-trophoblastic tumors like ovarian cancer (Searle et. aI., 1978), tumors ofthe breast (Home et. aI

  18. Biogenic silica in the Bay of Bengal during the southwest monsoon

    Digital Repository Service at National Institute of Oceanography (India)

    Gupta, G.V; Sarma, V.V

    stream_size 8 stream_content_type text/plain stream_name Oceanol_Acta_20_493.pdf.txt stream_source_info Oceanol_Acta_20_493.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  19. Structural analysis within the Rožná and Olší uranium deposits (Strážek Moldanubicum) for the estimation of deformation and stress conditions of underground gas storage

    Czech Academy of Sciences Publication Activity Database

    Ptáček, Jiří; Melichar, R.; Hájek, Antonín; Koníček, Petr; Souček, Kamil; Staš, Lubomír; Kříž, P.; Lazárek, J.

    2013-01-01

    Roč. 10, č. 2 (2013), s. 237-246 ISSN 1214-9705 Institutional support: RVO:68145535 Keywords : structural analysis * deformation * stress * underground gas storage Subject RIV: DH - Mining , incl. Coal Mining Impact factor: 0.667, year: 2013 http://www.irsm.cas.cz/materialy/acta_content/2013_02/acta_170_13_Ptacek_237-246.pdf

  20. Compositional variation of biotite from Variscan granitoids in central Europe: a statistic evaluation

    Czech Academy of Sciences Publication Activity Database

    Buda, G.; Koller, F.; Kovács, J.; Ulrych, Jaromír

    2004-01-01

    Roč. 45, č. 1 (2004), s. 21-37 ISSN 0365-8066 Institutional research plan: CEZ:AV0Z3013912 Keywords : biotite * major element composition * discriminant function analysis Subject RIV: DB - Geology ; Mineralogy http://www.sci.u-szeged.hu/asvanytan/acta/acta45fulltexts/AMP_buda_vol45.pdf

  1. Deformation Driven Alloying and Transformation

    Science.gov (United States)

    2015-03-03

    that originally were pure Cu. However, little Fe local consumption was observed. One of the examples is illustrated in the F-G-H range in the profile...113] Cram D, Zurob H, Brechet Y, Hutchinson C. Acta Mater 2009;57:5218. [114] Luton M, Sellars C. Acta Metall 1969;17:1033. [115] Sakai T, Jonas JJ

  2. Advances in membrane protein crystallography: in situ and in meso data collection

    International Nuclear Information System (INIS)

    Weyand, Simone; Tate, Christopher G.

    2015-01-01

    Membrane protein structural biology has made tremendous advances over the last decade but there are still many challenges associated with crystallization, data collection and structure determination. Two independent groups, Axford et al. [(2015), Acta Cryst. D71, 1228–1237] and Huang et al. [(2015), Acta Cryst. D71, 1238–1256], have published methods that make a major contribution to addressing these challenges

  3. Life history of the invasive bug Oxycarenus lavaterae (Heteroptera: Oxycarenidae) in Bulgaria

    Czech Academy of Sciences Publication Activity Database

    Nedvěd, Oldřich; Chehlarov, E.; Kalushkov, P.

    2014-01-01

    Roč. 66, č. 2 (2014), s. 203-208 ISSN 0324-0770 Institutional support: RVO:60077344 Keywords : size * weight * sexual dimorphism Subject RIV: EH - Ecology, Behaviour Impact factor: 0.532, year: 2014 http://www.acta-zoologica-bulgarica.eu/downloads/acta-zoologica-bulgarica/2014/66-2-203-208.pdf

  4. A first record of Perccottus glenii (Perciformes: Odontobutidae) in the Danube River in Bulgaria

    Czech Academy of Sciences Publication Activity Database

    Jurajda, Pavel; Vassilev, M.; Polačik, Matej; Trichkova, T.

    2006-01-01

    Roč. 58, č. 2 (2006), s. 279-282 ISSN 0324-0770 R&D Projects: GA MŠk LC522 Institutional research plan: CEZ:AV0Z60930519 Keywords : exotic species * Amur sleeper * Danube basin Subject RIV: EH - Ecology, Behaviour http://www.acta-zoologica-bulgarica.eu/downloads/acta-zoologica-bulgarica/2006/58-2-279-282.pdf

  5. Advances in membrane protein crystallography: in situ and in meso data collection

    Energy Technology Data Exchange (ETDEWEB)

    Weyand, Simone, E-mail: sw644@cam.ac.uk [Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA (United Kingdom); Tate, Christopher G., E-mail: sw644@cam.ac.uk [MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH (United Kingdom)

    2015-05-23

    Membrane protein structural biology has made tremendous advances over the last decade but there are still many challenges associated with crystallization, data collection and structure determination. Two independent groups, Axford et al. [(2015), Acta Cryst. D71, 1228–1237] and Huang et al. [(2015), Acta Cryst. D71, 1238–1256], have published methods that make a major contribution to addressing these challenges.

  6. Human Performance: Sex Differences and the Influence of the Menstrual Cycle (A Selected Bibliography)

    Science.gov (United States)

    1978-05-01

    Endocrinolo,, 1968, 28. 1269-1275. 9. JPinne, 0., Kontula, K., & Vihko, R. Review article: Mechanism of action of female sex steroids. Acta Obstetricia ...patterns of 8000 Finnish girls and their mothers. Acta Obstetricia et Gynecoloxica Scandinavica, 1971 .Supple- ment O, 1-36. 47I D. MENSTRUAL SYNCHRONY 1

  7. Leading the Charge: Governors, Higher Education and Accountability

    Science.gov (United States)

    American Council of Trustees and Alumni, 2014

    2014-01-01

    With this new tool, ACTA [American Council of Trustees and Alumni] is working to expand its outreach to governors nationwide on behalf of higher education reform, focusing on key issues of quality, cost, and accountability. ACTA has worked with governors and education leaders from across the country, and that experience has proven that innovative…

  8. Hydrothermal syntheses and single crystal structural ...

    Indian Academy of Sciences (India)

    Unknown

    21 300; Chesnut D J, Haushalter R C and Zubieta J. 1999 Inorg. Chim. Acta 292 41; Rarig Jr R S and. Zubieta J 2001 Inorg. Chim. Acta 312 188; LaDuca Jr. R L, Finn R and Zubieta J 1999 Chem. Commun. 1669. 34. SADABS 1996 v202: Area Detector Absorption Cor- rection, Siemens Industrial Automation, Inc., Madison,.

  9. Untitled

    African Journals Online (AJOL)

    Huhtikangas, Acta Chem. Scand.,. B28, 1209 (1974). M. Lounasmaa, Acta Chem. Scand., B31, 77 (1977). Paulos G. Yohannes and Ermias Dagne, SINET: Ethiop. J. Sci., 6, 31 (1983). B. Verdcourt and E.C. Trump, "Common Poisonous Plants of East Africa",. Collins, London, pp. 165-166 (1969). Haile Gabriel Dagne, Ethiop.

  10. Fulltext PDF

    Indian Academy of Sciences (India)

    Soumahoro T, Burkholder E, Ouellette W and Zubieta J. 2005 Inorg. Chim. Acta 358 606. 25. Jinghua L, Jun P, Enbo W, Lihua B and Shurong G 2000. J. Mol. Struct. 525 71. 26. Pope M T 1976 Inorg. Chem. 15 2068. 27. D'Amour H and Allmann R 1974 Naturwiss. 61 34. 28. Strandberg R 1975 Acta Chem. Scand. A 29 350.

  11. Endogenous protection derived from activin A/Smads transduction loop stimulated via ischemic injury in PC12 cells.

    Science.gov (United States)

    Mang, Jing; Mei, Chun-Li; Wang, Jiao-Qi; Li, Zong-Shu; Chu, Ting-Ting; He, Jin-Ting; Xu, Zhong-Xin

    2013-10-17

    Activin A (ActA), a member of transforming growth factor-beta (TGF-b) super- family, affects many cellular processes, including ischemic stroke. Though the neuroprotective effects of exogenous ActA on oxygen-glucose deprivation (OGD) injury have already been reported by us, the endogenous role of ActA remains poorly understood. To further define the role and mechanism of endogenous ActA and its signaling in response to acute ischemic damage, we used an OGD model in PC12 cells to simulate ischemic injury on neurons in vitro. Cells were pre-treated by monoclonal antibody against activin receptor type IIA (ActRII-Ab). We found that ActRII-Ab augments ischemic injury in PC12 cells. Further, the extracellular secretion of ActA as well as phosphorylation of smad3 in PC12 cells was also up-regulated by OGD, but suppressed by ActRII-Ab. Taken together, our results show that ActRII-Ab may augment ischemic injury via blocking of transmembrane signal transduction of ActA, which confirmed the existence of endogenous neuroprotective effects derived from the ActA/Smads pathway. ActRIIA plays an important role in transferring neuronal protective signals inside. It is highly possible that ActA transmembrance signaling is a part of the positive feed-back loop for extracellular ActA secretion.

  12. Endogenous Protection Derived from Activin A/Smads Transduction Loop Stimulated via Ischemic Injury in PC12 Cells

    Directory of Open Access Journals (Sweden)

    Zhong-Xin Xu

    2013-10-01

    Full Text Available Activin A (ActA, a member of transforming growth factor-beta (TGF-b super- family, affects many cellular processes, including ischemic stroke. Though the neuroprotective effects of exogenous ActA on oxygen-glucose deprivation (OGD injury have already been reported by us, the endogenous role of ActA remains poorly understood. To further define the role and mechanism of endogenous ActA and its signaling in response to acute ischemic damage, we used an OGD model in PC12 cells to simulate ischemic injury on neurons in vitro. Cells were pre-treated by monoclonal antibody against activin receptor type IIA (ActRII-Ab. We found that ActRII-Ab augments ischemic injury in PC12 cells. Further, the extracellular secretion of ActA as well as phosphorylation of smad3 in PC12 cells was also up-regulated by OGD, but suppressed by ActRII-Ab. Taken together, our results show that ActRII-Ab may augment ischemic injury via blocking of transmembrane signal transduction of ActA, which confirmed the existence of endogenous neuroprotective effects derived from the ActA/Smads pathway. ActRIIA plays an important role in transferring neuronal protective signals inside. It is highly possible that ActA transmembrance signaling is a part of the positive feed-back loop for extracellular ActA secretion.

  13. Copper Hazards to Fish, Wildlife, and Invertebrates: A Synoptic Review.

    Science.gov (United States)

    1998-01-01

    N. R. Rao. 1992. Accumulation of trace metals in the marine biota and their biological trans- port. Acta Botanica Indica 20:1 -5. Greig, R. A...Acta Botanica Indica20:71-75. Read, H. J., and M. H. Martin. 1993. The effect of heavy metals on populations of small mammals from wood- lands in

  14. Proceedings: NATO CCMS (Committee on the Challenges of Modern Society) Seminar Blue Book 159, Preservation of Flora and Fauna in Military Training Areas Held in Soesterberg, Netherlands on 28-30 November 1984

    Science.gov (United States)

    1987-01-01

    Zeilinge 1983. The effect of the heather beetle (Lochmea saturalis) on heather (Calluna vulgaris) as cause of mosaic patterns in heathlands. Acta Botanica ...Heathland management in th,. Netherlands scientific and social aims. Acta Botanica Neerlandica 32(3): 252. 1 1.53 EXCURSION TO THE STAKENBERC AREA ON

  15. The Successes and Failures of Democracy in the Post-Soviet Republics

    Science.gov (United States)

    2016-09-01

    Krouwel, “Measuring Presidentialism and Parliamentarism: An Application to Central and East European Countries,” Acta Politica 38 (2003): 333–364. 59...Measuring Presidentialism and Parliamentarism: An Application to Central and East European Countries.” Acta Politica 38 (2003): 333–364. Lane, David

  16. 154 Modélisation des conditions d'environnement des bocaux de ...

    African Journals Online (AJOL)

    youness

    [5] - N. KATERJI, M. HALLAIRE, A. PERRIER, R. DURAND, Acta. Oecologia, Oecol. Plant, 4 (1983) 11-26. [6] - J. W. DEARDORFF, J. Appl. Meteor., 16 (1977) 1182-1185. [7] - J. W. DEARDORFF, J. Geophys. Res., 83(C4) (1978) 1889-1903. [8] - T. KOSAI, Y. KOYAMA. and I. WATANABBE, Acta Hort., 230. (1988) 121-127.

  17. Cytogenetic investigations in Sciurus anomalus from Turkish Thrace (Rodentia: Sciuridae)

    Czech Academy of Sciences Publication Activity Database

    Arslan, A.; Zima, Jan

    2012-01-01

    Roč. 64, č. 4 (2012), s. 421-426 ISSN 0324-0770 Institutional support: RVO:68081766 Keywords : karyotype * C-banding * Ag-NOR staining * Caucasian squirrel * Turkey Subject RIV: EG - Zoology Impact factor: 0.309, year: 2012 http://www.acta-zoologica-bulgarica.eu/downloads/acta-zoologica-bulgarica/2012/64-4-421-426.pdf

  18. Synthesis, Characterization and Antimicrobial Activities of Some ...

    African Journals Online (AJOL)

    user

    of metal ions with vitamin.111: Synthesis and infrared spectra of metal complexes with pyridoxamine and pyridoxine. Inorg. Chim. Acta, 46, 191-197. Gary, J and Adeyemo, A (1981) Interaction of vitamin B1 with Zn(II), Cd (II) and Hg(II) in. Deuterated Dimethyl Sulfoxide. Inorg. Chim. Acta, 55, 93-98. Gohzalez-vergara, E ...

  19. Distribution of C-heterochromatin and nucleolar organizer regions in the karyotype of marbled polecat, Vormela peregusna (Carnivora: Mustelidae)

    Czech Academy of Sciences Publication Activity Database

    Arslan, A.; Zima, Jan

    2013-01-01

    Roč. 65, č. 4 (2013), s. 557-560 ISSN 0324-0770 Institutional support: RVO:68081766 Keywords : chromosomes * Ag-NOR staining * C-banding * Turkey Subject RIV: EG - Zoology Impact factor: 0.357, year: 2013 http://www.acta-zoologica-bulgarica.eu/downloads/acta-zoologica-bulgarica/2013/65-4-557-560.pdf

  20. High - velocity water jet impact on concrete samples

    Czech Academy of Sciences Publication Activity Database

    Mádr, V.; Uhlář, R.; Hlaváč, L. M.; Sitek, Libor; Foldyna, Josef; Hela, R.; Bodnárová, L.; Kaličinský, J.

    2009-01-01

    Roč. 2, č. 4 (2009), s. 43-48 ISSN 2067-3809 Institutional research plan: CEZ:AV0Z30860518 Keywords : water jet * concrete * depth of penetration * disintegration volume Subject RIV: JM - Building Engineering http://acta.fih.upt.ro/pdf/2009-4/ACTA-2009-4-08.pdf

  1. Bibliographie

    OpenAIRE

    Aliquot, Julien

    2012-01-01

    Abréviations Les abréviations sont celles de l'Année philologique, sauf exceptions reportées ci-dessous. AA(A)S : Annales archéologiques (arabes) syriennes, Damas. ACO : Acta conciliorum oecumenicorum, éd. E. Schwartz et al., Berlin, depuis 1914. Acta sanctorum : Acta sanctorum, collecta… a Sociis Bollandianis, 3e éd., Paris et Rome, depuis 1863. ADAJ : Annual of the Department of Antiquities of Jordan, Amman. AE : L’Année épigraphique, dans RA 1888-1961, puis sous la forme de volumes indépen...

  2. The crucial role of Activin A on the formation of primordial germ cell-like cells from skin-derived stem cells in vitro.

    Science.gov (United States)

    Sun, Rui; Sun, Yuan-Chao; Ge, Wei; Tan, Hui; Cheng, Shun-Feng; Yin, Shen; Sun, Xiao-Feng; Li, Lan; Dyce, Paul; Li, Julang; Yang, Xiao; Shi, Qing-Hua; Shen, Wei

    2015-01-01

    Primordial germ cells (PGCs) are founder cells of the germ cell lineage, and can be differentiated from stem cells in an induced system in vitro. However, the induction conditions need to be optimized in order to improve the differentiation efficiency. Activin A (ActA) is a member of the TGF-β super family and plays an important role in oogenesis and folliculogenesis. In the present study, we found that ActA promoted PGC-like cells (PGCLCs) formation from mouse skin-derived stem cells (SDSCs) in both embryoid body-like structure (EBLS) differentiation and the co-culture stage in a dose dependent manner. ActA treatment (100 ng/ml) during EBLS differentiation stage and further co-cultured for 6 days without ActA significantly increased PGCLCs from 53.2% to 82.8%, and as well as EBLS differentiation without ActA followed by co-cultured with 100 ng/ml ActA for 4 to 12 days with the percentage of PGCLCs increasing markedly in vitro. Moreover, mice treated with ActA at 100 ng/kg body weight from embryonic day (E) 5.5-12.5 led to more PGCs formation. However, the stimulating effects of ActA were interrupted by Smad3 RNAi, and in an in vitro cultured Smad3(-/-) mouse skin cells scenario. SMAD3 is thus likely a key effecter molecule in the ActA signaling pathway. In addition, we found that the expression of some epiblast cell markers, Fgf5, Dnmt3a, Dnmt3b and Wnt3, was increased in EBLSs cultured for 4 days or PGCLCs co-cultured for 12 days with ActA treatment. Interestingly, at 16 days of differentiation, the percentage of PGCLCs was decreased in the presence of ActA, but the expression of meiosis-relative genes, such as Stra8, Dmc1, Sycp3 and Sycp1, was increased. In conclusion, our data here demonstrated that ActA can promote PGCLC formation from SDSCs in vitro, at early stages of differentiation, and affect meiotic initiation of PGCLCs in later stages.

  3. People’s Republic of China Scientific Abstracts, Number 177

    Science.gov (United States)

    1977-10-06

    PAO [ARCHITECTURAL JOURNAL] No 2, June 1977 1 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 4, December 1976 13 CHIH-WU TSA-CHIH [JOURNAL OF BOTANY...10424 CSO: 4009 12 ACTA BOTANICA SINICA AUTHOR: None ORG: Three-in-one Combination Experimental Group of Peking Ch’ung-wen Vegetable Station...Physiological Processes of Stored Tomatoes" SOURCE: Peking CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] in Chinese Vol 18, No 4, Dec 76 pp 278-283 TEXT OF

  4. People’s Republic of China Scientific Abstracts, Number 195.

    Science.gov (United States)

    1978-08-01

    76 15 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 1, March 1978 16 TI-CHEN CHAN-HSIEN [EARTHQUAKE FRONT] No 2, April 1978 26 K𔃺-HSUEH...steril^UMs! and Consolidate the contradiction between the hsien and 6168 CSO: 8111/1528 15 ACTA BOTANICA SINICA AUTHOR: CHANG Te-i [l72B 1795...of Cultured Tobacco Cells" SOURCE: Peking CHIH-WU H5UEH-PA0 [_ACTA BOTANICA SINICÄ] in Chinese No 1, Mar 78 pp 1-5 TEXT OF ENGLISH ABSTRACT

  5. People’s Republic of China Scientific Abstracts, Number 201

    Science.gov (United States)

    1978-10-24

    original source materials or information as to the availability of full translations of these articles. CONTENTS PAGE CHIH-WU HSUEH-PAO [ACTA BOTANICA ...III - CC - 70 S § T] ACTA BOTANICA 5INICA AUTHOR: TS’AI Ch’i-kuei (5591 6386 6311 ] CH’IEN Ying-ch’ien [6929 66Q1 0241J CHDU...the Isolation and Culture of Rice (Qrvza sativa L.) Protoplasts" SOURCE: Peking CHIH-WU HSUEH-PA0 [ACTA BOTANICA SINICAj in Chinese No 2, Jun 78 pp

  6. JPRS Report. Science & Technology: China.

    Science.gov (United States)

    1989-05-16

    the Chemical Components of Illigera sp.s" ACTA BOTANICA SINICA, Vol 29, 1987 p 324. Hong Kangxin, et al., "Active Component of Medicinal Herb...2. Sun Jingsan, et al., ACTA BOTANICA SINICA, Vol 28 No 1, 1986 pp 33-37. 3. Sun Jingsan, et al., BOTANICAL BULLETIN, Vol 3 No 1, 1985 pp 47-48...63 8. Chen Huimin, et al., ACTA BOTANICA SINICA, Vol 22 No 2, 1980 pp 112-116. 9. Hao Shui, et al., "Proceedings of the Second Congress and

  7. Registration of randomized clinical trials

    DEFF Research Database (Denmark)

    Østervig, R M; Sonne, A; Rasmussen, L S

    2015-01-01

    the proportion of correctly registered randomized controlled trials (RCTs) published in Acta from 2009 to 2014. METHODS: We manually searched all Acta issues from 2009 to 2014 for RCTs. Information about timing of data collection and registration in trial registries was extracted. We classified RCTs as correctly...... starting enrolment before 2010 to 63.2% after 2010 (24/38, P clinical trials were registered at clinicaltrials.gov. CONCLUSION: Many published randomized controlled trials from Acta Anaesthesiologica Scandinavica were not adequately registered but the requirement of trial registration has...

  8. Blocking Blood Supply to Breast Carcinoma With a DNA Vaccine Encoding VEGF Receptor-2

    Science.gov (United States)

    2006-03-01

    vaccination: an update. Methods Mol Med 2003;87:377–90. 14. Ambrosini G, Adida C, Altieri DC. A novel anti- apoptosis gene, survivin, expressed in cancer...endothelial cells. Biochem Biophys Res Commun 1999;264:781–8. 26. O’Connor DS, Schechner JS, Adida C, et al. Control of apoptosis during angiogenesis by...minigene DNA vaccine protects mice from tumors of different origins by inducing a T cell-mediated suppression of tumor angiogenesis. From the Department of

  9. Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. I. Scaling of neutron data and the distributions of double bonds and water.

    OpenAIRE

    Wiener, M. C.; King, G. I.; White, S. H.

    1991-01-01

    We described in two previous papers a method for the joint refinement of the structure of fluid bilayers using neutron and x-ray diffraction data (Wiener, M. C., and S. H. White 1991a, b. Biophys. J. 59: 162-173 and 174-185). An essential part of the method is the appropriate scaling of the diffraction data. Here we describe the scaling of the neutron data and the determination of the transbilayer distribution of double bonds in liquid-crystalline (L alpha phase) phospholipid bilayers of 1,2-...

  10. Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. II. "Composition-space" refinement method.

    OpenAIRE

    Wiener, M C; White, S H

    1991-01-01

    This is the second of two papers describing a method for the joint refinement of the structure of fluid bilayers using x-ray and neutron diffraction data. We showed in the first paper (Wiener, M. C., and S. H. White. 1990. Biophys. J. 59:162-173) that fluid bilayers generally consist of a nearly perfect lattice of thermally disordered unit cells and that the canonical resolution d/hmax is a measure of the widths of quasimolecular components represented by simple Gaussian functions. The therma...

  11. Theoretical Modeling of Molecular Mechanisms, Time Scales, and Strains in Prion Diseases

    Science.gov (United States)

    2006-07-01

    folds . Prog. Biophys. Mol. Biol. 77:111-175. 12 Mobley, D.L. , D.L. Cox, R.R.P. Singh, M.W. Maddox, and M.L. Longo. 2004. Modeling amyloid beta...a site can also vary from PrPC to PrPSc. Rules vary depending on the model being explored, but the basic procedure is the same. For every simulation...DSTP model straightens these loops, adds more possible hydrogen bonds in the loop region, and preserves the putative monomer-monomer spacing and 3- fold

  12. The C proteins of HeLa 40S nuclear ribonucleoprotein particles exist as anisotropic tetramers of (C1)3 C2.

    OpenAIRE

    Barnett, S F; Friedman, D L; LeStourgeon, W M

    1989-01-01

    The C proteins (C1 and C2) of HeLa 40S heterogeneous nuclear ribonucleoprotein particles copurify under native conditions as a stable complex with a fixed molar protein ratio (S.F. Barnett, W.M. LeStourgeon, and D.L. Friedman, J. Biochem. Biophys. Methods 16:87-97, 1988). Gel filtration chromatography and velocity sedimentation analyses of these complexes revealed a large Stokes radius (6.2 nm) and a sedimentation coefficient of 5.8S. On the basis of these values and a partial specific volume...

  13. Unbiased Combinatorial Genomic Approaches to Identify Alternative Therapeutic Targets within the TSC Signaling Network

    Science.gov (United States)

    2015-09-01

    double strand breaks in Escherichia coli DNA. Biochem Biophys Res Commun 93, 1110-1113 (1980); published online EpubApr 29 ( 59. M. R. Koelle, W. S...round of PCR amplification using Precision Melt Supermix (Bio-Rad) and nested primers to generate a product bp in length (95°C 3min, 50 rounds of [95...analyzed using HRMAnalyzer, available at www.flyrnai.org/HRMA. See Table S6 for primer sequences. Sequence verification of clones Genomic DNA was

  14. Molecular cloning and genomic organization of a second probable allatostatin receptor from Drosophila melanogaster

    DEFF Research Database (Denmark)

    Lenz, C; Williamson, M; Grimmelikhuijzen, C J

    2000-01-01

    We (C. Lenz et al. (2000) Biochem. Biophys. Res. Commun. 269, 91-96) and others (N. Birgül et al. (1999) EMBO J. 18, 5892-5900) have recently cloned a Drosophila receptor that was structurally related to the mammalian galanin receptors, but turned out to be a receptor for a Drosophila peptide...... with a Drosophila genomic database clone that contained a DNA sequence coding for a protein having, again, structural similarities with the rat galanin receptors. Using PCR with primers coding for the presumed exons of this second Drosophila receptor gene, 5'- and 3'-RACE, and Drosophila cDNA as template, we...

  15. Application of TensorFlow to recognition of visualized results of fragment molecular orbital (FMO) calculations

    OpenAIRE

    Saitou, Sona; Iijima, Jun; Fujimoto, Mayu; Mochizuki, Yuji; Okuwaki, Koji; Doi, Hideo; Komeiji, Yuto

    2018-01-01

    We have applied Google's TensorFlow deep learning toolkit to recognize the visualized results of the fragment molecular orbital (FMO) calculations. Typical protein structures of alpha-helix and beta-sheet provide some characteristic patterns in the two-dimensional map of inter-fragment interaction energy termed as IFIE-map (Kurisaki et al., Biophys. Chem. 130 (2007) 1). A thousand of IFIE-map images with labels depending on the existences of alpha-helix and beta-sheet were prepared by employi...

  16. Disease: H01396 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available the base of the brain. Cerebrovascular disease RNF213 [HSA:57674] ACTA2 [HSA:59] ...isease is associated with the compensatory development of abnormally thin and fragile collateral vessels at

  17. Vanas stiilis väitekiri ja kaitsmine / Urve Lippus

    Index Scriptorium Estoniae

    Lippus, Urve, 1950-2015

    2014-01-01

    Arvustus: Tyrväinen, Helena. Kohti Kalevala-sarjaa : identiteetti, eklektisyys ja Ranskan jälki Uuno Klamin musiikissa. Helsinki : Suomen musiikkitieteellinen seura : Suomen musiikkikirjastoyhdistys, 2013. (Acta musicologica Fennica ; 30)

  18. VISIÓN GENERAL DE LA EVALUACIÓN DEL RIESGO EN SALUD INFANTIL EMPLEANDO UN ENFOQUE POR ETAPAS DE DESARROLLO (American translation is: Overview of a Life Stage Approach to Children's Health Risk Assessment)

    Science.gov (United States)

    Discussing the challenges associated with estimating and interpreting toxicant exposures and health risks from biomonitoring data. This extended abstract was translated in Spanish and published in Acta Toxicologica Argentina.

  19. Tallinna Ülikooli kirjastus tegi uue raamatusarja

    Index Scriptorium Estoniae

    2013-01-01

    Tallinna Ülikooli kirjastus hakkas välja andma uut raamatusarja "Acta Universitatis Tallinnensis. Artes", mille avaraamatuks on Katrin Kivimaa koostatud artiklikogumik "Working with Feminism: Curating and Exhibitions in Eastern Europe"

  20. Molecular cloning and characterization of a pathogen- related ...

    African Journals Online (AJOL)

    ajl yemi

    2011-12-26

    related protein properties. Plant Cell Environ. 23: 1227-. 1236. Zhang R, Wang YC, Liu GF, Li HY (2010) Cloning and characterization of a pathogenesis-related gene (ThPR10) from Tamarix Hispida. Acta. Biol. Cracov. Bot.

  1. complexes of Ciprofloxacin

    African Journals Online (AJOL)

    SERVER

    2007-12-17

    2002). Magnesium, Calcium and Barium Percholate complexes of ciprofloxacin and Norfloxacin. Acta. Chim. Slov. 49: 457-466. Akanji MA, Olagoke OA, Oloyede OB (1993). Effects of chronic consumption of metabisulphite on ...

  2. Prevalence and phenotypes of congenital myopathy due to α-actin 1 gene mutations

    DEFF Research Database (Denmark)

    Witting, Nanna; Werlauff, Ulla; Duno, Morten

    2016-01-01

    INTRODUCTION: Congenital myopathy due to mutations in the α-actin 1 gene (ACTA1) was identified in 1999, but knowledge of prevalence and phenotype in patients who survive 5 years is lacking. METHODS: A national cohort of 91 patients aged ≥5 years and diagnosed with congenital myopathy was assessed...... for ACTA1 mutations and investigated clinically. RESULTS: Four patients with ACTA1 mutations were identified, yielding a prevalence of 4.4%. Patients were 10-23 years of age, and all but 1 were ambulatory. Vital capacity ranged from 47% to 70% predicted, and 1 patient needed nocturnal bi-level positive...... airway pressure. Limb flexor/extensor muscles and upper and lower extremities were affected equally. Pronounced neck flexor weakness was noted. CONCLUSIONS: Congenital myopathy caused by ACTA1 mutations is fatal in infancy in most cases. This study shows that the prevalence of α-actin myopathy in older...

  3. Disease: H00032 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available (carcinogen) ... AUTHORS ... Hall P, Holm LE. ... TITLE ... Radiation-associated thyroid cancer--facts and fiction. ... JOURNAL ... Acta Oncol 37:325-30 (1998) DOI:10.1080/028418698430539 ...

  4. [The Reception of Medieval Europa in the Baltic Sea Region. Papers of the XIIth Visby Symposium held at Gotland University, Visby] / Stefan Donecker

    Index Scriptorium Estoniae

    Donecker, Stefan, 1977-

    2011-01-01

    Arvustus : The Reception of Medieval Europa in the Baltic Sea Region. Papers of the XIIth Visby Symposium held at Gotland University, Visby. Viby : Gotland University Press, 2009. (Acta Visbyensia. 12)

  5. QMU in Integrated Spacecraft System Models Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ACTA and Sandia National Laboratories propose to quantify and propagate substructure modeling uncertainty for reduced-order substructure models to higher levels of...

  6. Genetics Home Reference: 48,XXYY syndrome

    Science.gov (United States)

    ... and 49,XXXXY syndromes: not just variants of Klinefelter syndrome. Acta Paediatr. 2011 Jun;100(6):851-60. ... on PubMed Central Visootsak J, Graham JM Jr. Klinefelter syndrome and other sex chromosomal aneuploidies. Orphanet J Rare ...

  7. Chromosomal Aberrations in Monozygotic and Dizygotic Twins Versus Singletons in Denmark During 1968-2009

    DEFF Research Database (Denmark)

    Kristensen, Lone Krøldrup; Larsen, Lisbeth A; Fagerberg, Christina

    2017-01-01

    BACKGROUND: Hall (Embryologic development and monozygotic twinning. Acta Geneticae Medicae et Gemellologiae, Vol. 45, 1996, pp. 53-57) hypothesized that chromosomal aberrations can lead to monozygotic (MZ) twinning. However, twinning and chromosomal aberrations increase prenatal mortality and could...

  8. KERKWEES IN DIE

    African Journals Online (AJOL)

    KERKWEES IN DIE BRANDING: DIE NEDERDUITSE GEREFORMEERDE. KERK IN ALGEMENE SINODALE VERBAND. 1994-2011. ACTA THEOLOGICA. Supplementum 18. 2013. INHOUD. HOOFSTUK 1 Verantwoording. 1. HOOFSTUK 2 Die Sinode van versoening? 4. HOOFSTUK 3 Bestendiging in 'n nuwe bedeling.

  9. Uso de los Datos de Biomonitoreo para Informar sobre la Evaluacion Infantil (American translation is: USING BIOMONITORING DATA TO INFORM EXPOSURE ASSESSMENT IN CHILDREN)

    Science.gov (United States)

    Discussing the challenges associated with estimating and interpreting toxicant exposures and health risks from biomonitoring data. This extended abstract was translated in Spanish and published in Acta Toxicologica Argentina.

  10. No crisis but methodological separatism

    DEFF Research Database (Denmark)

    Erola, Jani; Reimer, David; Räsänen, Pekka

    2015-01-01

    This article compares methodological trends in nationally and internationally oriented sociology using data from the articles of three Nordic sociological journals: one international (Acta Sociologica), one Finnish (Sosiologia), and one Danish (Dansk Sociologi). The data consists of 943 articles ...

  11. African Journal of Neurological Sciences - 2009 Vol. 28 No 1

    African Journals Online (AJOL)

    Keywords : myasthenia, spondylarthropathy, autoimmune diseases, ankylosing spondylitis. RESUME. Propos ... We report the case of an association : myasthenia-spondylarthropathy which is an original observation because this .... myasthenia gravis: autoimmune diseases and their relation to thymectomy. Acta Neurol ...

  12. The catalogue of Ichneumon wasps of Slovakia (Hymenoptera: Ichneumonidae). Part I: A checklist of the subfamily Cryptinae with 32 new records

    Czech Academy of Sciences Publication Activity Database

    Rindoš, Michal; Lukáš, J.; Zeman, V.; Holecová, M.

    2017-01-01

    Roč. 65, č. 1 (2017), s. 167-170 ISSN 1211-8516 Institutional support: RVO:60077344 Keywords : Cryptinae * Hymenoptera * Ichneumonidae Subject RIV: EG - Zoology OBOR OECD: Zoology https://acta.mendelu.cz/65/1/0167/

  13. Age, growth and distribution of the Antarctic fish Chaenocephalus aceratus based on otoliths

    Directory of Open Access Journals (Sweden)

    Ryszard Jacek Traczyk

    2015-10-01

    Żabrowski, M. 2000. The osteology and ossification variability of the skull of antarctic white-blooded fish Chaenodraco wilsoni Regan, 1914 (Channichthyidae, Notothenioidei. W-wa : Acta Icht. Piscat. 30 (2: 111-126.

  14. Genetics Home Reference: Miller-Dieker syndrome

    Science.gov (United States)

    ... Support and Advocacy Resources (2 links) Brain Foundation (Australia) National Organization for Rare Disorders (NORD): Lissencephaly GeneReviews ( ... Pizzardi G, Del Balzo F, Iannetti P. Neuronal migration disorders: clinical, neuroradiologic and genetics aspects. Acta Paediatr. ...

  15. Structural studies on a non-toxic homologue of type II RIPs from ...

    Indian Academy of Sciences (India)

    2015-11-28

    82. Feizi T 2000 Carbohydrate-mediated recognition systems in innate immunity. Immunol. Rev. 173 79–88. French S and Wilson K 1978 On the treatment of negative intensity observations. Acta Crystallogr. A34 517–525.

  16. Appendix 3: The analytical outline for ironic speech acts: short version

    African Journals Online (AJOL)

    Abstract. Book Title: The story of Jesus and the blind man: A speech act reading of John 9. Book Author: Hisayasu Ito. Ritsumeikan University, Kyoto City, Japan. Acta Theologica, Supplementum 21 2015.

  17. Estonia : [2012] / Allan Sikk

    Index Scriptorium Estoniae

    Sikk, Allan, 1975-

    2013-01-01

    Ülevaade Eesti valitsuses 2012. aastal toimunud muutustest, sisepoliitika olulisematest arengutest (protestid ACTA vastu, Rahvakogu kokkutulek, Silvergate, opositsiooni tegevus, arutelud ESM-i ümber, venekeelsest koolist Eestis)

  18. Mysids (Crustacea) from the salt pans of Mumbai, India, with a description of a new species

    Digital Repository Service at National Institute of Oceanography (India)

    Biju, A.; Panampunnayil, S.U.

    on Marine Science, University of Tokyo 256–273. Quintero C, de Roa EZ. 1973. Notas bioecologicas sobre Metamysidopsis insularis Brattegard (Crusatacea-Mysidacea) en una laguna litoral de Venezuela. Acta Biologica Venezuelica 8: 245-278. Ramamoorthy K...

  19. [The reception of medieval Europe in the Baltic Sea region, Papers of the XIIth Visby Symposium held at Gotland University, Visby] / Juhan Kreem

    Index Scriptorium Estoniae

    Kreem, Juhan, 1971-

    2011-01-01

    Arvustus: The reception of medieval Europe in the Baltic Sea Region : papers of the XIIth Visby Symposium, held at Gotland University, Visby / editor: Jörn Staecker. Visby : Gotland University Press, 2009. (Acta Visbyensia ; 12)

  20. ORIGINAL ARTICLE

    African Journals Online (AJOL)

    User

    HIV/AIDS) were not selected. ... 400 Precision, Memmert, Germany). Identification and Counting of Bacterial Iso- lates. Bacterial ..... policy implications for home management strate- gies. Acta Trop 90, 211-214. Musa-Aisien A., Ibadin M., Ukoh G.

  1. Eye features in three Danish patients with multisystemic smooth muscle dysfunction syndrome

    DEFF Research Database (Denmark)

    Moller, Hans Ulrik; Fledelius, Hans C; Milewicz, Dianna M

    2012-01-01

    A de novo mutation of the ACTA2 gene encoding the smooth muscle cell α-actin has been established in patients with multisystemic smooth muscle dysfunction syndrome associated with patent ductus arteriosus and mydriasis present at birth....

  2. Elusiyan et al., Afr J Tradit Complement Altern Med. (2011) 8(1):27-33

    African Journals Online (AJOL)

    USER

    -276. 22. Sticher O, Afifi-Yazar FU. (1979). Minecoside and verminoside, two new iridoid glucosides from Veronica officinalis L. (Scrophulariaceae). Helvetica Chimica Acta, 62 (56): 535-539. 23. Tietze LF. (1983). Secologanin, a biogenetic key ...

  3. Preface

    Science.gov (United States)

    Jung, Young Mee; Baranska, Malgorzata

    2018-05-01

    This special issue of the Spectrochimica Acta A is dedicated to the retirement of Professor Yukihiro Ozaki of Kwansei Gakuin University, Japan as an internationally well recognized scientist in molecular spectroscopy studies including vibrational and electronic spectroscopy.

  4. Surgical Excision Of A Craniopharynginoma By Transcallosal ...

    African Journals Online (AJOL)

    complaints included: polydipsia and polyuria in one case, progressive hypopsia in the second case; headache in the third case; and hormonal manifestations in the .... Intraventricular craniopharyngiomas: topographical classification and surgical approach selection based on an extensive overview. Acta Neurochir , 2004 ,.

  5. Sistemas de transporte inteligentes en cruces fronterizos internacionales : un estudio abarcador : facilitando el comercio y mejorando la seguridad en el transporte

    Science.gov (United States)

    2001-04-01

    El Programa de Permisosen Fronteras Internacionales (IBC por sus siglas en ingls) fue iniciado bajo la previsin del Acta de Eficiencia de Transporte Terrestre Intermodal (ISTEA por sus siglas en ingls) en 1991. El programa fue concebido origina...

  6. The Role of Similarity Cues in the Development of Trust in Sources of Information About GM Food

    NARCIS (Netherlands)

    Ragoisha, G.A.; Bondarenko, A.S.; Osipovich, N.P.; Rabchynski, S.M.; Streltsov, E.A.; Gutteling, Jan M.

    2009-01-01

    An approach to multiparametric characterisation of variable electroactive interfaces based on potentiodynamic electrochemical impedance spectroscopy (PDEIS) [G.A. Ragoisha, A.S. Bondarenko, Electrochim. Acta 50 (2005) 1553] has been extended to atomic multilayer assembly monitoring. The multilayers

  7. Suitability of gramineous plants as food for the phytophagous ladybird Cynegetis impunctata L. (Coleoptera: Coccinellidae)

    Czech Academy of Sciences Publication Activity Database

    Kalushkov, P.; Chehlarov, E.; Nedvěd, Oldřich

    2013-01-01

    Roč. 65, č. 4 (2013), s. 561-564 ISSN 0324-0770 Grant - others:GA JU(CZ) 144/2010/100 Institutional support: RVO:60077344 Keywords : grass * development time * body mass Subject RIV: GF - Plant Pathology, Vermin, Weed, Plant Protection Impact factor: 0.357, year: 2013 http://www.acta-zoologica-bulgarica.eu/downloads/acta-zoologica-bulgarica/2013/65-4-561-564.pdf

  8. Proceedings of the Conference on Knowledge-Based Software Assistant (5th) Held in Liverpool, New York on 24-28 September 1990

    Science.gov (United States)

    1991-03-01

    Structure and Design of Global Search Algorithms. Tech. Rep.KES.U.87.12, Kestrel Institute, November 1987. to appear in Acta Informatica . Smith, D.R. KIDS...Aiken P, Palmer, J.D., " ReDe : Hypermedia-based Software Supporting Requirements Engineering" Technical Report.- Center for Software Systems Engineering...Wirsing. Crypt-equivalent algebraic specifications. Acta Informatica , 25(2):111-153, February 1988. (C󈨕] M. H. Cheheyl et al. Verifying security

  9. Specification and Verification of Secure Concurrent and Distributed Software Systems

    Science.gov (United States)

    1992-02-01

    reduce in SERUPNOZ : *%tsIde(v(v(p(ep(p(0)))) rewite: 23 result Zero: 0 rede In SOUNDOU : outside (op(v(V(r(p(0)))) rewrites: 19 result 2254t: I...Transactions On Programming Languages And Systems, 6(2):159-174, 1984. 252 [BW821 M. Broy and M. Wirsing. Partial abstract types. Acta Informatica , 18, 1982...Acta Informatica , 24, 1987. [DE82] R. Dannenberg and G. Ernst. Formal program verification using symbolic execution. IEEE Transactions on Software

  10. short communication development of an indirect spectrophotometric

    African Journals Online (AJOL)

    B. S. Chandravanshi

    6. Yeoh, C.B.; Kuntom, A.; Dorasamy, S.; Omar, M.R.; Nor, M.Y.M.; Noh, M.R.M. Eur. J. Lipid Sci. Technol. 2006, 108, 960. 7. Galeano, D.T.; Guiberteau, C.A.; Espinosa, M.A.; Lopez, S.M.D. Anal. Chim. Acta 2008,. 618, 131. 8. Ni, Y.; Qiu, P.; Kokot, S. Anal. Chim. Acta 2004,516, 7. 9. Pereira, L.A.; Rath, S. Anal. Bioanal. Chem.

  11. Hydrogen bonding in thiobenzamide synthon and its Cadmium ...

    Indian Academy of Sciences (India)

    Seena E B, Kurup M R P and Suresh E 2008 J. Chem. Crystallogr. 38 93. 25. Mahmood-ul-Hassan K, Shahid H, Tashfeen A and. Jason D M 2009 Acta Cryst. E65 1128. 26. Mahmood-ul-Hassan K, Shahid H, Tashfeen A and. Jason D M 2009 Acta Cryst. E65 1333. 27. Mahmood-ul-Hassan K, Shahid H, Tashfeen A and.

  12. Current Induced Seismicity in the Paskov Mine Field

    Czech Academy of Sciences Publication Activity Database

    Holub, Karel; Rušajová, Jana; Holečko, J.

    2013-01-01

    Roč. 10, č. 2 (2013), s. 181-187 ISSN 1214-9705 R&D Projects: GA MŠk LM2010008 Institutional support: RVO:68145535 Keywords : Ostrava-Karviná coal mines * seismic network * induced seismicity * location plot Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 0.667, year: 2013 http://www.irsm.cas.cz/materialy/acta_content/2013_02/acta_170_07_%20Holub_181-187.pdf

  13. China Report, Economic Affairs, Energy: Status and Development -- XXVI

    Science.gov (United States)

    1984-04-09

    better technology for open-cut mining; — renovating 9 railway trunk lines while building 8 new ones, bringing the total number in the area up to 20 and...CSO: 4013/119 91 SUPPLEMENTAL SOURCES CHINA’S SOLAR ENERGY RESOURCE DISTRIBUTION ANALYZED Beijing TAIYANGNENG XUEBAO [ACTA ENERGIAE SOLARIS...Calculation in Our Country, TAIYANGNENG XUEBAO [ACTA ENERGIAE SOLARIS SINICA], Vol 1, 1980 pp 1-9. 12553 CSO: 4013/19 102 CONSERVATION CONSERVATION

  14. The ichthyofauna of the shoreline zone in the longitudinal profile of the Danube River, Bulgaria

    Czech Academy of Sciences Publication Activity Database

    Polačik, Matej; Trichkova, T.; Janáč, Michal; Vassilev, M.; Jurajda, Pavel

    2008-01-01

    Roč. 60, č. 1 (2008), s. 77-88 ISSN 0324-0770 R&D Projects: GA MŠk LC522 Grant - others:National Science Fund(BG) B-1510/05 Institutional research plan: CEZ:AV0Z60930519 Keywords : Lower Danube * shoreline zone * fish community * distribution * abundance * endangered species Subject RIV: EH - Ecology, Behaviour http://www.acta-zoologica-bulgarica.eu/downloads/acta-zoologica-bulgarica/2008/60-1-077-088.pdf

  15. Chest wall reconstruction with acellular dermal matrix (Strattice™) and a TRAM flap

    DEFF Research Database (Denmark)

    Brunbjerg, Mette Eline; Juhl, Alexander Andersen; Damsgaard, Tine Engberg

    2014-01-01

    Mette Eline Brunbjerg, Alexander Andersen Juhl, Tine E. Damsgaard. "Chest wall reconstruction with acellular dermal matrix (Strattice™) and a TRAM flap.” Acta Oncol. 2013 Jun;52(5):1052-4. Epub 2012 Oct 24. PMID: 23095144......Mette Eline Brunbjerg, Alexander Andersen Juhl, Tine E. Damsgaard. "Chest wall reconstruction with acellular dermal matrix (Strattice™) and a TRAM flap.” Acta Oncol. 2013 Jun;52(5):1052-4. Epub 2012 Oct 24. PMID: 23095144...

  16. Study of the effect of moisture content and bending rate on the fracture toughness of rocks

    Czech Academy of Sciences Publication Activity Database

    Vavro, Leona; Souček, Kamil

    2013-01-01

    Roč. 10, č. 2 (2013), s. 247-253 ISSN 1214-9705 R&D Projects: GA MŠk ED2.1.00/03.0082 Institutional support: RVO:68145535 Keywords : fracture toughness * bending rate * tensile strength Subject RIV: DB - Geology ; Mineralogy Impact factor: 0.667, year: 2013 http://www.irsm.cas.cz/materialy/acta_content/2013_02/acta_170_14_Vavro_Soucek_247-253.pdf

  17. Fulltext PDF

    Indian Academy of Sciences (India)

    Administrator

    Nagasaki Y and Kataoka K 2003 Anal. Chem. 75. 6124. 10. Wang G-L, Yuan J-L, Gong B-L, Matsumoto K and. Hu Z-D 2001 Anal. Chim. Acta 448 165. 11. Belanger L, Sylvestre C and Dufour D 1973 Clin. Chim. Acta 48 15. 12. Aguilar Z P, Vandaveer W R and Fritsch I 2002 Anal. Chem. 74 3321. 13. Wang J 2006 Biosens.

  18. Nanoscale grain growth behaviour of CoAl intermetallic synthesized ...

    Indian Academy of Sciences (India)

    Administrator

    Lee J, Zhou F, Chung K H, Kim N J and Lavernia E J 2001. Metall. Mater. Trans. 32 3109. Liu F, Yang G, Wang H, Chen Z and Zhou Y 2006 Thermo- chim. Acta 443 212. Liu K W and Mucklich F 2001 Acta Mater. 49 395. Mousavi T, Karimzadeh F and Abbasi M H 2008 Mater. Sci. Eng. 487 46. Nakamura R and Iijima Y 2005 ...

  19. Structural and stress analysis of mining practice in the Upper Silesian Coal Basin

    Czech Academy of Sciences Publication Activity Database

    Waclawik, Petr; Ptáček, Jiří; Grygar, R.

    2013-01-01

    Roč. 10, č. 2 (2013), s. 255-265 ISSN 1214-9705 Institutional support: RVO:68145535 Keywords : horizontal stress * structural analysis * mine roadway stability * coal mining * rock burst Subject RIV: DH - Mining, incl. Coal Mining Impact factor: 0.667, year: 2013 http://www.irsm.cas.cz/materialy/acta_content/2013_02/acta_170_15_Waclawik_255-265.pdf

  20. High temperature oxidation of Ti–48Al–8Cr–2Ag alloy with sputtered ...

    Indian Academy of Sciences (India)

    Administrator

    Brady M P, Smialke J L and Humphray D L 1997a Acta Metall. Meter. 45 2371. Brady M P, Smialke J L and Smith J 1997b Acta Metall. Meter. 45 2357. Dettenwanger F, Schumann E, Ruhle M, Rakowski J and Meier. G H 1998 Oxid Met. 50 269. Fukumoto M, Hara M and Nagataki T 2004 Oxid. Met. 61 1. Kim Y M 1989 J. Met.

  1. A Bibliography on the Chemical Weathering of Granitic Rocks

    Science.gov (United States)

    1988-09-01

    Figuerda, H. 1970. (Observations of weathering a,d morphology of granitic blocks, El Roble Mountain). Revista Geografica de Valparaiso, vol. 4, pp. 64-68...weathering of granite. Geochimica et Cosmochimica Acta , vol. 48, pp. 1249-1255. Moeyersons, J. 1977. Joint patterns and their influence on the form of...transported quartz grains from the Harney Peak granite, Black Hills, South Dakota. Geochimica et Cosmochimica Acta , vol. 43, pp. 137-146. Pye, K. 1986

  2. Kinetics and equilibria for the axial ligation of bromomethyl (aqua ...

    Indian Academy of Sciences (India)

    Administrator

    Sci.) 114 11. 14. Brown K L 1986 Organo metallic synthesis (eds) R B. King and J J Eisch (Amestardam: Elseiver) 3 186. 15. Brown K L 1979 Inorg. Chim. Acta. 37 513. 16. Marques H M, Egan T J, Marsh J H, Mellor J R and. Munro O K 1989 Inorg. Chim. Acta 166 249. 17. Lever A B P 1968 Inorganic electronic spectroscopy.

  3. Activin A accelerates the progression of fetal oocytes throughout meiosis and early oogenesis in the mouse.

    Science.gov (United States)

    Liang, Gui-Jin; Zhang, Xi-Feng; Wang, Jun-Jie; Sun, Yuan-Chao; Sun, Xiao-Feng; Cheng, Shun-Feng; Li, Lan; De Felici, Massimo; Shen, Wei

    2015-10-15

    Activins can exert several roles in ovary development. However, little is known about their involvement in early mammalian oogenesis. In this study, we reported that activin receptors (including ActRIA, ActRIB, ActRIIA, and ActRIIB) are expressed throughout the development of the mouse ovaries from 12.5 days postcoitum (dpc) to 21 days postparturition (dpp). Moreover, we found that in vitro, the addition of activin A (ActA) to the culture medium of 12.5 dpc ovarian tissues accelerated the progression of oocytes throughout meiotic prophase I stages. This result was reproduced in vivo following administration of ActA to pregnant mice. The in vitro effect of ActA was associated with increased expression of premeiotic and meiotic genes (including Dazl, Spo11, Stra8, Scp3, and Rec8) in the ovarian tissues. Mechanistically, ActA-dependent SMAD3 signaling modulated the expression of members of the retinoic acid (RA) system, including the RA degradation CYP26B1 enzyme and the RA receptors. Finally, ActA promoted the survival and growth of fetal and early postnatal oocytes and primordial follicle assembly both in vitro and in vivo. In conclusion, the present study identifies new roles of ActA in early oogenesis and suggested that ActA and RA might cooperate in promoting meiosis in female germ cells.

  4. In vitro wear gap formation of self-adhesive resin cements: a CLSM evaluation.

    Science.gov (United States)

    Belli, Renan; Pelka, Matthias; Petschelt, Anselm; Lohbauer, Ulrich

    2009-12-01

    To evaluate the depth of wear gaps of new self-adhesive cements after toothbrush abrasion and ACTA wear test. Luting spaces (325+/-25 microm width, 2mm depth) were produced in Empress 2 ceramic blocks with a diamond saw to obtain flat substrate segments for toothbrush abrasion (n=24) and ACTA wear (n=27). After etching and silanization, the slits were filled with 8 self-adhesive cements, 2 conventional resin cements and 1 flowable composite, stored for 2 weeks in distilled water at 37 degrees C and planished to the cement level. Toothbrush abrasion was carried out in a toothbrush simulator (Willytec, Germany) for 20,000 cycles (load 1N) using an abrasive slurry based on a commercial toothpaste (Elmex, Gaba, Germany, RDA=77). The ACTA wear experiment was performed following the ACTA protocol in millet seed slurry for 400,000 cycles (Willytec). The gap replicas were measured for vertical wear loss under a confocal laser scanning microscope (CLSM). The data were analyzed using one-way ANOVA and a mod-LSD test at pGrandio Flow. Grandio Flow and AllCem showed to be the most resistant to the ACTA wear test, while SpeedCem the least resistant. No correlation was found between the two wear test experiments. Self-adhesive cements have good wear resistance to toothbrush abrasion but most of them wear more rapidly under higher loads in the ACTA test than conventional resin cements and flowable composites.

  5. Population Density and Moment-based Approaches to Modeling Domain Calcium-mediated Inactivation of L-type Calcium Channels.

    Science.gov (United States)

    Wang, Xiao; Hardcastle, Kiah; Weinberg, Seth H; Smith, Gregory D

    2016-03-01

    We present a population density and moment-based description of the stochastic dynamics of domain [Formula: see text]-mediated inactivation of L-type [Formula: see text] channels. Our approach accounts for the effect of heterogeneity of local [Formula: see text] signals on whole cell [Formula: see text] currents; however, in contrast with prior work, e.g., Sherman et al. (Biophys J 58(4):985-995, 1990), we do not assume that [Formula: see text] domain formation and collapse are fast compared to channel gating. We demonstrate the population density and moment-based modeling approaches using a 12-state Markov chain model of an L-type [Formula: see text] channel introduced by Greenstein and Winslow (Biophys J 83(6):2918-2945, 2002). Simulated whole cell voltage clamp responses yield an inactivation function for the whole cell [Formula: see text] current that agrees with the traditional approach when domain dynamics are fast. We analyze the voltage-dependence of [Formula: see text] inactivation that may occur via slow heterogeneous domain [[Formula: see text

  6. Mechanism for action of electromagnetic fields on cells.

    Science.gov (United States)

    Panagopoulos, Dimitris J; Karabarbounis, Andreas; Margaritis, Lukas H

    2002-10-18

    A biophysical model for the action of oscillating electric fields on cells, presented by us before [Biochem. Biophys. Res. Commun. 272(3) (2000) 634-640], is extended now to include oscillating magnetic fields as well, extended to include the most active biological conditions, and also to explain why pulsed electromagnetic fields can be more active biologically than continuous ones. According to the present theory, the low frequency fields are the most bioactive ones. The basic mechanism is the forced-vibration of all the free ions on the surface of a cell's plasma membrane, caused by an external oscillating field. We have shown that this coherent vibration of electric charge is able to irregularly gate electrosensitive channels on the plasma membrane and thus cause disruption of the cell's electrochemical balance and function [Biochem. Biophys. Res. Commun. 272(3) (2000) 634-640]. It seems that this simple idea can be easily extended now and looks very likely to be able to give a realistic basis for the explanation of a wide range of electromagnetic field bioeffects.

  7. Elastic neutron scattering study of proton dynamics in glycerol

    Science.gov (United States)

    Cornicchi, Elena; Cinelli, Stefania; Natali, Francesca; Onori, Giuseppe; Paciaroni, Alessandro

    2004-07-01

    A recent neutron scattering investigation on lysozyme embedded in glycerol-water mixtures has shown that solvent dynamics is crucial in determining the dynamical properties of the biomolecule itself (Biophys. J. 83 (2002) 1157). To better understand the role played by solvent, we have performed an elastic incoherent neutron scattering (INS) experiment as a function of the temperature on pure glycerol. To directly compare the dynamics of the solvated protein and that of the pure solvent, we settled the same experimental conditions and applied the same data analysis procedure as in Paciaroni et al. (Biophys. J. 83 (2002) 1157). By using a double-well model and taking into account for the global molecular diffusion, we exploited the measured intensity to estimate the mean square displacements (MSD) of glycerol hydrogen atoms. We found that the total MSD deviate from the low-temperature vibrational harmonic trend at approximately T=235K, consistent with the value of the critical temperature reported in literature (Phys. Rev. E 55 (1997) 3183). The present investigation suggests that the internal dynamics of glycerol molecules, i.e. the vibrations and reorientations of hydrogen atoms relative to the molecular centre of mass (c.o.m.), can be put in relationship with the protein dynamics.

  8. Elastic neutron scattering study of proton dynamics in glycerol

    International Nuclear Information System (INIS)

    Cornicchi, Elena; Cinelli, Stefania; Natali, Francesca; Onori, Giuseppe; Paciaroni, Alessandro

    2004-01-01

    A recent neutron scattering investigation on lysozyme embedded in glycerol-water mixtures has shown that solvent dynamics is crucial in determining the dynamical properties of the biomolecule itself (Biophys. J. 83 (2002) 1157). To better understand the role played by solvent, we have performed an elastic incoherent neutron scattering (INS) experiment as a function of the temperature on pure glycerol. To directly compare the dynamics of the solvated protein and that of the pure solvent, we settled the same experimental conditions and applied the same data analysis procedure as in Paciaroni et al. (Biophys. J. 83 (2002) 1157). By using a double-well model and taking into account for the global molecular diffusion, we exploited the measured intensity to estimate the mean square displacements (MSD) of glycerol hydrogen atoms. We found that the total MSD deviate from the low-temperature vibrational harmonic trend at approximately T=235 K, consistent with the value of the critical temperature reported in literature (Phys. Rev. E 55 (1997) 3183). The present investigation suggests that the internal dynamics of glycerol molecules, i.e. the vibrations and reorientations of hydrogen atoms relative to the molecular centre of mass (c.o.m.), can be put in relationship with the protein dynamics

  9. Binding and dissociation kinetics using fractals: an analysis of electrostatic effects and randomly coupled and oriented coupled receptors on biosensor surfaces.

    Science.gov (United States)

    Butala, Harshala D; Sadana, Ajit

    2004-03-15

    A fractal analysis is used to analyze the influence of: (a) electrostatic interactions on binding and dissociation rate coefficients for antibodies HH8, HH10, and HH26 in solution to hen egg-white lysozyme (HEL) immobilized on a sensor chip surface [Biophys. J. 83 (2002) 2946]; and (b) the binding and dissociation of recombinant Fab in solution to random NHS-coupled Cys-HEL and oriented thiol-coupled Cys-HEL immobilized on a sensor chip surface [Methods 20 (2000) 310]. Single- and dual-fractal models were employed to fit the data. Values of the binding and the dissociation rate coefficient(s) and the fractal dimensions were obtained from a regression analysis provided by Corel Quattro Pro 8.0 (Corel Corporation Limited, Ottawa, Canada. 1997). The binding rate coefficients are quite sensitive to the degree of heterogeneity on the sensor chip surface. It is of interest to compare the results obtained by the fractal analysis with that of the original analysis [Biophys. J. 83 (2002) 2946]. For example, as one goes from the binding of 21 nM HH10/HEL to the binding of 640 nM HH10/HEL(K97A), Sinha et al. [Biophys. J. 83 (2002) 29461 indicate that the enhancement of diffusional encounter rates may be due to 'electrostatic steering' (a long-range interaction). Our analysis indicates that there is an increase in the value of the fractal dimension, Df1 by a factor of 1.12 from a value of 2.133-2.385. This increase in the degree of heterogeneity on the surface leads to an increase in the binding rate coefficient, k1 by a factor of 1.59 from 12.92 to 20.57. The fractal analysis of binding and dissociation of recombinant Fab in solution to random NHS-coupled Cys-HEL and oriented thiol-coupled Cys-HEL immobilized on a sensor chip [Methods 20 (2000) 310] surface are consistent with the degree of heterogeneity present on the sensor chip surface for the random and the oriented case. As expected, the random case will exhibit a higher degree of heterogeneity than the oriented case

  10. Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression.

    Directory of Open Access Journals (Sweden)

    Gianina Ravenscroft

    Full Text Available Mutations in the skeletal muscle α-actin gene (ACTA1 cause congenital myopathies including nemaline myopathy, actin aggregate myopathy and rod-core disease. The majority of patients with ACTA1 mutations have severe hypotonia and do not survive beyond the age of one. A transgenic mouse model was generated expressing an autosomal dominant mutant (D286G of ACTA1 (identified in a severe nemaline myopathy patient fused with EGFP. Nemaline bodies were observed in multiple skeletal muscles, with serial sections showing these correlated to aggregates of the mutant skeletal muscle α-actin-EGFP. Isolated extensor digitorum longus and soleus muscles were significantly weaker than wild-type (WT muscle at 4 weeks of age, coinciding with the peak in structural lesions. These 4 week-old mice were ~30% less active on voluntary running wheels than WT mice. The α-actin-EGFP protein clearly demonstrated that the transgene was expressed equally in all myosin heavy chain (MHC fibre types during the early postnatal period, but subsequently became largely confined to MHCIIB fibres. Ringbinden fibres, internal nuclei and myofibrillar myopathy pathologies, not typical features in nemaline myopathy or patients with ACTA1 mutations, were frequently observed. Ringbinden were found in fast fibre predominant muscles of adult mice and were exclusively MHCIIB-positive fibres. Thus, this mouse model presents a reliable model for the investigation of the pathobiology of nemaline body formation and muscle weakness and for evaluation of potential therapeutic interventions. The occurrence of core-like regions, internal nuclei and ringbinden will allow analysis of the mechanisms underlying these lesions. The occurrence of ringbinden and features of myofibrillar myopathy in this mouse model of ACTA1 disease suggests that patients with these pathologies and no genetic explanation should be screened for ACTA1 mutations.

  11. Actin Nemaline Myopathy Mouse Reproduces Disease, Suggests Other Actin Disease Phenotypes and Provides Cautionary Note on Muscle Transgene Expression

    Science.gov (United States)

    Ravenscroft, Gianina; Jackaman, Connie; Sewry, Caroline A.; McNamara, Elyshia; Squire, Sarah E.; Potter, Allyson C.; Papadimitriou, John; Griffiths, Lisa M.; Bakker, Anthony J.; Davies, Kay E.; Laing, Nigel G.; Nowak, Kristen J.

    2011-01-01

    Mutations in the skeletal muscle α-actin gene (ACTA1) cause congenital myopathies including nemaline myopathy, actin aggregate myopathy and rod-core disease. The majority of patients with ACTA1 mutations have severe hypotonia and do not survive beyond the age of one. A transgenic mouse model was generated expressing an autosomal dominant mutant (D286G) of ACTA1 (identified in a severe nemaline myopathy patient) fused with EGFP. Nemaline bodies were observed in multiple skeletal muscles, with serial sections showing these correlated to aggregates of the mutant skeletal muscle α-actin-EGFP. Isolated extensor digitorum longus and soleus muscles were significantly weaker than wild-type (WT) muscle at 4 weeks of age, coinciding with the peak in structural lesions. These 4 week-old mice were ∼30% less active on voluntary running wheels than WT mice. The α-actin-EGFP protein clearly demonstrated that the transgene was expressed equally in all myosin heavy chain (MHC) fibre types during the early postnatal period, but subsequently became largely confined to MHCIIB fibres. Ringbinden fibres, internal nuclei and myofibrillar myopathy pathologies, not typical features in nemaline myopathy or patients with ACTA1 mutations, were frequently observed. Ringbinden were found in fast fibre predominant muscles of adult mice and were exclusively MHCIIB-positive fibres. Thus, this mouse model presents a reliable model for the investigation of the pathobiology of nemaline body formation and muscle weakness and for evaluation of potential therapeutic interventions. The occurrence of core-like regions, internal nuclei and ringbinden will allow analysis of the mechanisms underlying these lesions. The occurrence of ringbinden and features of myofibrillar myopathy in this mouse model of ACTA1 disease suggests that patients with these pathologies and no genetic explanation should be screened for ACTA1 mutations. PMID:22174871

  12. Scientometric Analysis of the Journals of the Academy of Medical Sciences in Bosnia and Herzegovina.

    Science.gov (United States)

    Masic, Izet; Begic, Edin; Zunic, Lejla

    2016-02-01

    Currently in Bosnia and Herzegovina there are 25 journals in the field of biomedicine, 6 of them are indexed in Medline/PubMed base (Medical Archives, Materia Socio-Medica, Acta Informatica Medica, Acta Medica Academica, Bosnian Journal of Basic Medical Sciences (BJBMS) and Medical Glasnik), and one (BJBMS) is indexed in Science Citation Index Expanded (SCIE)/Web of Science base. The aim of this study was to show the scope of work of the journals that were published by Academy of Medical Sciences of Bosnia and Herzegovina - Medical Archives, Materia Socio-Medica and Acta Informatica Medica. The research presents a meta-analysis of three journals, or their issues, during the calendar year 2015 (retrospective and descriptive character). During 2015 calendar year a total of 286 articles were published (in Medical Archives 104 (36.3%), in Materia Socio-Medica 99 (34.6%), and in Acta Informatica Medica 83 (29%)). Original articles are present in the highest number in all three journals (in Medical Archives 80.7%, in Materia Socio Medica 77.7%, and in Acta Informatica Medica 68.6%). In Medical Archives, 90.3% of the articles were related to the field of clinical medicine. In Materia Socio-Medica, the domain of clinical medicine and public health was the most represented. Preclinical areas are most frequent in Acta Informatica Medica. The period of 50-60 days for a decision on the admission of article is most common in all three journals, with trend of shortening of that period. Articles came from 19 countries, mostly from Bosnia and Herzegovina, then from Iran, Kosovo, Saudi Arabia and Greece. In Medical Archives original articles in the field of clinical medicine (usually internal and surgical disciplines) are most often present, and that is the case in last four years. The number of articles in Materia Socio-Medica and Acta Informatica Medica is growing from year to year. In Materia Socio-Medica there is a trend of growth of articles in the field of public health

  13. La conferencia de petrópolis y el tratado interamericano de asistencia recíproca en río de janeiro en 1947

    OpenAIRE

    Caicedo Castilla, José Joaquín

    2010-01-01

    Capítulo I: 1. Origen del Acta de Chapultepec; 2. El acta de Chapultepec; 3. Convocatoria de una nueva conferencia; 4. Gobiernos asistentes. Capítulo II -- Crónica de la conferencia: 1. Sesión inaugural; 2. Organización de la conferencia; 3. El debate general. Capítulo III -- Preámbulo del tratado: 1. Relaciones entre la ONU y el Panamericanismo; 2. Principios de Derecho Internacional; 3. Antecedentes; 4. El proyecto colombiano; 5. Política de paz; 6. La protección internacional de los derech...

  14. The Importance of Fine-Scale Flow Processes and Food Availability in the Maintenance of Soft-Sediment Communities

    Science.gov (United States)

    1993-02-01

    Khripounoff. 1980. Un cas de colonization rapide d’un sediment profond . Oceanolozica Acta, 3, 285-291. Eckman, J.E. (1979) Small-scale patterns and...untangling the existing web of ideas on animal-sediment relationships. We conclude by again stating that it may not be possible, in some cases, to decouple...Liment profond . Oceanologica Acta, 3, 285-291. Desbruybres, D., J.W. Deming, A. Dinet and A. Khripounoff. 1985. Reactions de l’dcosyst~me benthique

  15. Criticism of the Pap Smear as a Diagnostic Tool in Cervical Cancer Screening.

    Science.gov (United States)

    Schneider, Volker

    2017-01-01

    This editorial by Dr. Leopold G. Koss appeared in the January 1980 issue of Acta Cytologica. It addressed recent critical opinions in the general media on cervical screening and its costs. It marked the beginning of a more critical approach to cytology by the lay press, health care providers, and epidemiologists. It was also the first of a series of highly informative editorials by Dr. Koss that illustrated the critical issues of cytology during the 1980s. The elegance and clarity of his articles reflect the high standard of editorial writing in Acta Cytologica at this time. These articles are reviewed and excerpts are presented. © 2017 S. Karger AG, Basel.

  16. Nobel prize awards in radiochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Adloff, J.P. [Strasbourg Univ. (France)

    2012-07-01

    In 1996 the Editors of Radiochimica Acta brought out a special volume of the journal to celebrate the hundredth anniversary of the discovery of radioactivity. On the occasion of the 50{sup th} anniversary of Radiochimica Acta, which follows closely upon the centenary of Marie Curie's second Nobel Prize in 1911, the author has the privilege to informally review 'Radiochemistry and Nobel Prize Awards', including discoveries of radioelements and new fields in chemistry based on radiochemical methods. (orig.)

  17. Phenotypes, genotypes, and prevalence of congenital myopathies older than 5 years in Denmark

    DEFF Research Database (Denmark)

    Witting, Nanna; Werlauff, Ulla; Duno, Morten

    2017-01-01

    .3% NEB mutations. Less than 5% had mutations in ACTA1, TPM2/3, MTM1, TTN, SEPN1, or SC4NA. A genetic cause was established in 83% with specific histology (cores/rods/centronuclear myopathy) vs 29% with unspecific histology. The detailed clinical examination found gene-dependent discrepancies...... in the pattern of muscle affection and walking ability. Although walking ability was delayed in patients with ACTA1, TPM2/3, and RYR1 mutations, it was within normal limits in patients with NEB and DNM2 mutations. CONCLUSIONS: We found that overall, genetic and histologic prevalence of congenital myopathy...

  18. The Coherence of Acoustic Signals in the Ocean and Application to the Design of Very Large Arrays

    Science.gov (United States)

    1979-01-01

    Selected Paners of Norbert Wiener , MIT Press, Cambridge, Massachusetts, 1964. *"[10] L. H. Koopmans, The Spectral Analysis of Time Series, Academic Press...from the Russian), McQraw-Hiil, New York, 1961. 13] N. Wiener , "Generalized Harmonic Analysis," Acta Math. 55. Re- printed in Selected Papers of Norbert ...Vol. 56, No. 2, AL’Pust 1974. Wiener . N., "Gentralized Harmonic Analysis." Acta Math, 55, reprinted In Selected Pq rD of Norbert .Lner ...ITT Press, Cambridge, Mass., 3964. I ~~ Af&A

  19. Reaction Kinetics of Rocket Propellant Gases. 1. Rate of Decomposition of Nitric Oxide at Elevated Temperatures and Appendix

    Science.gov (United States)

    1950-03-27

    Explosion," Ada Physicochimica URSS , 21:577, 1946. ) 15. Polyakov, M. V., and Genkina, R. J., "On the Mechanism of’Formation of Nitrogen...Oxides in Explosions of Combustible Mixtures," Acta Physicochimica URSS , 11:443, 1939. Page 18 jjia*nn«r a JPL Progress Report No. g-4g REFERENCES...Cont’d) 16. Fi-an-k-Kamenetzky, D., "The Formation of Nitric Oxide During Combustion and Explosion," Acta Physicochimica URSS , 23:27, 1947

  20. Mechanism of rigid overlaying of carboniferous strata failure in face mining in the case of multiseams deposit

    Czech Academy of Sciences Publication Activity Database

    Jiránková, E.; Staš, Lubomír; Kajzar, Vlastimil; Doležalová, Hana

    2013-01-01

    Roč. 10, č. 2 (2013), s. 189-195 ISSN 1214-9705 R&D Projects: GA MŠk ED2.1.00/03.0082; GA MV VG20102014034 Institutional support: RVO:68145535 Keywords : subsidence trough * rock mass * overlaying strata * longwall mining * tensor stress measurement Subject RIV: DH - Mining, incl. Coal Mining Impact factor: 0.667, year: 2013 http://www.irsm.cas.cz/materialy/acta_content/2013_02/acta_170_08_Jirankova_189-195.pdf