Bioanalysis Young Investigator: Sadagopan Krishnan.
Krishnan, Sadagopan
2011-05-01
Supervisor's supporting comments. I am pleased to recommend Sadagopan Krishnan for the Bioanalysis Young Investigator award. Sadagopan is a bright, creative and highly-motivated young bioanalytical chemist. His theses in our laboratory involved the development of electrochemiluminescent arrays for chemical toxicity screening utilizing cytochrome P450 metalloenzymes. He was senior author of a paper in Analytical Chemistry on this that was featured on the cover. He also investigated fundamental properties of human metabolic cytochrome P450s - research was carried out at his own initiative, and explains for the first time the role of iron spin state on enzyme electron transfer rates. He then developed thin films that mimic the natural cytochrome P450 redox cycle for the first time. He worked with several other group members to develop a superparamagnetic labeling scheme for immunosensing of proteins by surface plasmon resonance at unprecedented low levels, down to 10 fg/ml. Sadagopan has also demonstrated strong leadership skills. After his PhD, Sadagopan joined the group of Fraser Armstrong at Oxford University, UK, as a postdoctoral fellow. He is currently expanding his research horizons into the area of biofuel cells. His eventual goal is to join the faculty of a major university and build a world-class research group in bioanalytical chemistry.
Bioanalysis young investigator: Maria Rambla-Alegre.
Rambla-Alegre, Maria
2012-06-01
in creating a good atmosphere within the department. She is a bright and highly efficient person to work with. For all these reasons, I can only strongly recommend Maria to be awarded the Bioanalysis Young Investigator Award.
Wilson, Amanda; Silvester, Stephen; Woods, Karen
2014-05-01
Retaining regulated bioanalysis within AstraZeneca (AZ) is important for the effective delivery of nonclinical and clinical bioanalysis. The focus for the in-house team is the delivery of high-throughput bioanalysis and toxicokinetics support for investigational toxicology; however, by retaining GLP compliance, AZ will have an in-house understanding of every candidate drug that is progressed into development by supporting the first rodent GLP study for each project. The majority of nonclinical bioanalysis and all of the clinical bioanalysis are delivered by two external partnership models. This article describes the key benefits of retaining GLP compliance, the partnership interactions, discusses the management of non-GLP support in a GLP environment and how, having practical experience of regulatory facing method development, validation and study execution adds value to the AZ portfolio delivery.
Outsourcing in bioanalysis: a CRO perspective.
Lowes, Stephen
2017-08-01
Steve Lowes from Q 2 Solutions speaks to Sankeetha Nadarajah, Managing Commissioning Editor: about outsourcing strategy implementation. Steve started his industrial career at VG Biotech in the UK that became the LC-MS instrument entity of Waters Corporation. Since joining the CRO group that became Advion and then Q 2 Solutions, his career has focused on regulated bioanalysis with particular emphasis on LC-MS. He is a founding member of the Global Bioanalysis Consortium and a past-chair of the AAPS Bioanalytical Focus Group. At Q 2 Solutions, Steve leads the scientific disciplines around LC-MS bioanalysis for both small molecule and biomolecule applications including biomarker assays. Steve has over 40 peer-reviewed publications on bioanalysis and is a frequent speaker at national and international conferences.
Stevenson, Lauren; Amaravadi, Lakshmi; Myler, Heather; Salazar-Fontana, Laura; Gorovits, Boris; Kirshner, Susan; Xue, Li; Garofolo, Fabio; Alley, Stephen C; Thway, Theingi; Joyce, Alison; Bansal, Surendra; Beaver, Chris; Bergeron, Annik; Cai, Xiao-Yan; Cojocaru, Laura; DeSilva, Binodh; Dumont, Isabelle; Fluhler, Eric; Fraser, Stephanie; Gouty, Dominique; Gupta, Swati; Haidar, Sam; Hayes, Roger; Ingelse, Benno; Ishii-Watabe, Akiko; Kaur, Surinder; King, Lindsay; Laterza, Omar; Leung, Sheldon; Lévesque, Ann; Ma, Mark; Petit-Frere, Corinne; Pillutla, Renuka; Rose, Mark; Schultz, Gary; Smeraglia, John; Swanson, Steven; Torri, Albert; Vazvaei, Faye; Wakelin-Smith, Jason; Wilson, Amanda; Woolf, Eric; Yang, Tong-Yuan
2014-01-01
The 2014 8th Workshop on Recent Issues in Bioanalysis (8th WRIB), a 5-day full immersion in the evolving field of bioanalysis, took place in Universal City, California, USA. Close to 500 professionals from pharmaceutical and biopharmaceutical companies, contract research organizations and regulatory agencies worldwide convened to share, review, discuss and agree on approaches to address current issues of interest in bioanalysis. The topics covered included both small and large molecules, and involved LCMS, hybrid LBA/LCMS, LBA approaches and immunogenicity. From the prolific discussions held during the workshop, specific recommendations are presented in this 2014 White Paper. As with the previous years' editions, this paper acts as a practical tool to help the bioanalytical community continue advances in scientific excellence, improved quality and better regulatory compliance. Due to its length, the 2014 edition of this comprehensive White Paper has been divided into three parts for editorial reasons. This publication (Part 3) covers the recommendations for Large molecules bioanalysis using LBA and Immunogenicity. Part 1 (Small molecules bioanalysis using LCMS) and Part 2 (Hybrid LBA/LCMS, Electronic Laboratory Notebook and Regulatory Agencies' Input) were published in the Bioanalysis issues 6(22) and 6(23), respectively.
Fluhler, Eric; Hayes, Roger; Garofolo, Fabio; Dumont, Isabelle; Blaye, Olivier Le; Arnold, Mark; Bansal, Surendra; Verhaeghe, Tom; Wilson, Amanda; Stevenson, Lauren; Myler, Heather; Bauer, Ronald; Bergeron, Annik; Bustard, Mark; Cai, Xiao-Yan; Carbone, Mary; Cojocaru, Laura; Desai-Krieger, Daksha; Duggan, Jeff; Haidar, Sam; Ho, Stacy; Ingelse, Benno; Katori, Noriko; Lévesque, Ann; Lowes, Steve; Ma, Mark; Mettke, Katalina; Michon, Josée; Musuku, Adrien; Olah, Timothy; Patel, Shefali; Rose, Mark; Schultz, Gary; Smeraglia, John; Spooner, Neil; Stouffer, Bruce; Vazvaei, Faye; Wakelin-Smith, Jason; Wang, Jian; Welink, Jan; Whale, Emma; Woolf, Eric; Xue, Li; Yang, Tong-Yuan
2014-01-01
The 2014 8th Workshop on Recent Issues in Bioanalysis (8th WRIB), a 5-day full immersion in the evolving field of bioanalysis, took place in Universal City, California, USA. Close to 500 professionals from pharmaceutical and biopharmaceutical companies, contract research organizations and regulatory agencies worldwide convened to share, review, discuss and agree on approaches to address current issues of interest in bioanalysis. The topics covered included both small and large molecules, and involved LCMS, hybrid LBA/LCMS, LBA approaches and immunogenicity. From the prolific discussions held during the workshop, specific recommendations are presented in this 2014 White Paper. As with the previous years' editions, this paper acts as a practical tool to help the bioanalytical community continue advances in scientific excellence, improved quality and better regulatory compliance. Due to its length, the 2014 edition of this comprehensive White Paper has been divided into three parts for editorial reasons. This publication (Part 1) covers the recommendations for small molecule bioanalysis using LCMS. Part 2 (Hybrid LBA/LCMS, Electronic Laboratory Notebook and Regulatory Agencies' input) and Part 3 (Large molecules bioanalysis using LBA and Immunogenicity) will be published in the upcoming issues of Bioanalysis.
Dufield, Dawn; Neubert, Hendrik; Garofolo, Fabio; Kirkovsky, Leo; Stevenson, Lauren; Dumont, Isabelle; Kaur, Surinder; Xu, Keyang; Alley, Stephen C; Szapacs, Matthew; Arnold, Mark; Bansal, Surendra; Haidar, Sam; Welink, Jan; Le Blaye, Olivier; Wakelin-Smith, Jason; Whale, Emma; Ishii-Watabe, Akiko; Bustard, Mark; Katori, Noriko; Amaravadi, Lakshmi; Aubry, Anne-Françoise; Beaver, Chris; Bergeron, Annik; Cai, Xiao-Yan; Cojocaru, Laura; DeSilva, Binodh; Duggan, Jeff; Fluhler, Eric; Gorovits, Boris; Gupta, Swati; Hayes, Roger; Ho, Stacy; Ingelse, Benno; King, Lindsay; Lévesque, Ann; Lowes, Steve; Ma, Mark; Musuku, Adrien; Myler, Heather; Olah, Timothy; Patel, Shefali; Rose, Mark; Schultz, Gary; Smeraglia, John; Swanson, Steven; Torri, Albert; Vazvaei, Faye; Wilson, Amanda; Woolf, Eric; Xue, Li; Yang, Tong-Yuan
2014-01-01
The 2014 8th Workshop on Recent Issues in Bioanalysis (8th WRIB), a 5-day full immersion in the evolving field of bioanalysis, took place in Universal City, California, USA. Close to 500 professionals from pharmaceutical and biopharmaceutical companies, contract research organizations and regulatory agencies worldwide convened to share, review, discuss and agree on approaches to address current issues of interest in bioanalysis. The topics covered included both small and large molecules, and involved LCMS, hybrid LBA/LCMS, LBA approaches and immunogenicity. From the prolific discussions held during the workshop, specific recommendations are presented in this 2014 White Paper. As with the previous years' editions, this paper acts as a practical tool to help the bioanalytical community continue advances in scientific excellence, improved quality and better regulatory compliance. Due to its length, the 2014 edition of this comprehensive White Paper has been divided into three parts for editorial reasons. This publication (Part 2) covers the recommendations for Hybrid LBA/LCMS, Electronic Laboratory Notebook and Regulatory Agencies' Input. Part 1 (Small molecules bioanalysis using LCMS) was published in the Bioanalysis issue 6(22) and Part 3 (Large molecules bioanalysis using LBA and Immunogenicity) will be published in the Bioanalysis issue 6(24).
Workshop on Recent Issues in Bioanalysis (WRIB) Poster Award winners 2017.
Simmons, Neil; Lowe, John; Coddens, Annelies
2017-07-01
The 11th WRIB held in Los Angeles, CA, USA in April 2017. It drew over 750 professionals representing large Pharmas, Biotechs, CROs and multiple regulatory agencies from around the world, from the global bioanalytical community. Bioanalysis and Bioanalysis Zone are very proud to be supporting the WRIB Poster Awards again this year, and we feature the profiles of the authors of the winning posters. Visit www.bioanalysis-zone.com to see the winning posters in full.
Zheng, Naiyu; Jiang, Hao; Zeng, Jianing
2014-09-01
Robotic liquid handlers (RLHs) have been widely used in automated sample preparation for liquid chromatography-tandem mass spectrometry (LC-MS/MS) bioanalysis. Automated sample preparation for regulated bioanalysis offers significantly higher assay efficiency, better data quality and potential bioanalytical cost-savings. For RLHs that are used for regulated bioanalysis, there are additional requirements, including 21 CFR Part 11 compliance, software validation, system qualification, calibration verification and proper maintenance. This article reviews recent advances in automated sample preparation for regulated bioanalysis in the last 5 years. Specifically, it covers the following aspects: regulated bioanalysis requirements, recent advances in automation hardware and software development, sample extraction workflow simplification, strategies towards fully automated sample extraction, and best practices in automated sample preparation for regulated bioanalysis.
Optofluidic bioanalysis: fundamentals and applications
Directory of Open Access Journals (Sweden)
Ozcelik Damla
2017-03-01
Full Text Available Over the past decade, optofluidics has established itself as a new and dynamic research field for exciting developments at the interface of photonics, microfluidics, and the life sciences. The strong desire for developing miniaturized bioanalytic devices and instruments, in particular, has led to novel and powerful approaches to integrating optical elements and biological fluids on the same chip-scale system. Here, we review the state-of-the-art in optofluidic research with emphasis on applications in bioanalysis and a focus on waveguide-based approaches that represent the most advanced level of integration between optics and fluidics. We discuss recent work in photonically reconfigurable devices and various application areas. We show how optofluidic approaches have been pushing the performance limits in bioanalysis, e.g. in terms of sensitivity and portability, satisfying many of the key requirements for point-of-care devices. This illustrates how the requirements for bianalysis instruments are increasingly being met by the symbiotic integration of novel photonic capabilities in a miniaturized system.
Recent development in software and automation tools for high-throughput discovery bioanalysis.
Shou, Wilson Z; Zhang, Jun
2012-05-01
Bioanalysis with LC-MS/MS has been established as the method of choice for quantitative determination of drug candidates in biological matrices in drug discovery and development. The LC-MS/MS bioanalytical support for drug discovery, especially for early discovery, often requires high-throughput (HT) analysis of large numbers of samples (hundreds to thousands per day) generated from many structurally diverse compounds (tens to hundreds per day) with a very quick turnaround time, in order to provide important activity and liability data to move discovery projects forward. Another important consideration for discovery bioanalysis is its fit-for-purpose quality requirement depending on the particular experiments being conducted at this stage, and it is usually not as stringent as those required in bioanalysis supporting drug development. These aforementioned attributes of HT discovery bioanalysis made it an ideal candidate for using software and automation tools to eliminate manual steps, remove bottlenecks, improve efficiency and reduce turnaround time while maintaining adequate quality. In this article we will review various recent developments that facilitate automation of individual bioanalytical procedures, such as sample preparation, MS/MS method development, sample analysis and data review, as well as fully integrated software tools that manage the entire bioanalytical workflow in HT discovery bioanalysis. In addition, software tools supporting the emerging high-resolution accurate MS bioanalytical approach are also discussed.
Interview with Xiaoli Wang PhD winner of CACA 2016 Young Investigator Award
Directory of Open Access Journals (Sweden)
Xiaoli Wang
2016-07-01
Full Text Available Xiaoli Wang is currently an R&D Senior Scientist in Agilent’s HPLC instrument R&D group at Agilent Technologies, Waldbronn, Germany. Prior to this, he was an R&D manager in Agilent’s CrossLab Group in the US focusing on development of novel chromatographic columns. He has a B.S. degree in Chemistry from Peking University, Beijing China and a PhD. degree in Analytical Chemistry from the University of Minnesota in 2006. He started his industrial career in the pharmaceutical industry at AstraZeneca for four years before joining Agilent Technologies in 2010. Recently, he won the prestigious 2016 Young Investigator Award from Chinese American Chromatography Association (CACA. This interview was conducted by Roland J.W. Meesters PhD, Editor-in-Chief of Journal of Applied Bioanalysis.
[Sample preparation and bioanalysis in mass spectrometry].
Bourgogne, Emmanuel; Wagner, Michel
2015-01-01
The quantitative analysis of compounds of clinical interest of low molecular weight (sample preparation. Sample preparation is a crucial part of chemical/biological analysis and in a sense is considered the bottleneck of the whole analytical process. The main objectives of sample preparation are the removal of potential interferences, analyte preconcentration, and converting (if needed) the analyte into a more suitable form for detection or separation. Without chromatographic separation, endogenous compounds, co-eluted products may affect a quantitative method in mass spectrometry performance. This work focuses on three distinct parts. First, quantitative bioanalysis will be defined, different matrices and sample preparation techniques currently used in bioanalysis by mass spectrometry of/for small molecules of clinical interest in biological fluids. In a second step the goals of sample preparation will be described. Finally, in a third step, sample preparation strategies will be made either directly ("dilute and shoot") or after precipitation.
Recent Progress in Aptamer-Based Functional Probes for Bioanalysis and Biomedicine.
Zhang, Huimin; Zhou, Leiji; Zhu, Zhi; Yang, Chaoyong
2016-07-11
Nucleic acid aptamers are short synthetic DNA or RNA sequences that can bind to a wide range of targets with high affinity and specificity. In recent years, aptamers have attracted increasing research interest due to their unique features of high binding affinity and specificity, small size, excellent chemical stability, easy chemical synthesis, facile modification, and minimal immunogenicity. These properties make aptamers ideal recognition ligands for bioanalysis, disease diagnosis, and cancer therapy. This review highlights the recent progress in aptamer selection and the latest applications of aptamer-based functional probes in the fields of bioanalysis and biomedicine. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Principles of Vibrational Spectroscopic Methods and their Application to Bioanalysis
DEFF Research Database (Denmark)
Moore, David S.; Jepsen, Peter Uhd; Volka, Karel
2014-01-01
imaging, fiber optic probes for in vivo and in vitro analysis, and methods to obtain depth profile information. The issue of fluorescence interference will be considered from the perspectives of excitation wavelength selection and data treatment. Methods to optimize signal to noise with minimized...... excitation laser irradiance to avoid sample damage are also discussed. This chapter then reviews applications of Raman spectroscopy to bioanalysis. Areas discussed include pathology, cytopathology, single-cell analysis, in vivo and in vitro tissue characterization, chemical composition of cell components...... as conformation of DNA and proteins), vibrations of inter- and intramolecular hydrogen bonds in solid-state materials, as well as picosecond dynamics in liquid solutions. This chapter reviews modern instrumentation and techniques for THz spectroscopy, with emphasis on applications in bioanalysis....
Bioanalysis-related highlights from the 2011 AAPS National Biotechnology Conference.
Crisino, Rebecca M; Dulanto, Beatriz
2011-08-01
The American Association of Pharmaceutical Scientists is a dynamic international forum for the exchange of knowledge among scientists to enhance their contributions to drug development. The annual National Biotechnology Conference, conducted and organized by the American Association of Pharmaceutical Scientists, is a forum dedicated to advancements in science and technology related to discovery, development and manufacture of medical biotechnology products. The 2011 National Biotechnology Conference meeting convened in San Francisco, CA, USA on 16-18 May. Over 300 abstracts were submitted and approximately 50 sessions examined topics pertaining to advances in drug development, emerging analytical technologies, bioanalysis-related issues, biosimilar therapies, updates on global regulatory documents and expectations, and other topics. The focus of this article is to highlight key developments relevant to immunogenicity and pharmacokinetic drug concentration bioanalysis.
Lowes, Steve; Jersey, Jim; Shoup, Ronald; Garofolo, Fabio; Savoie, Natasha; Mortz, Ejvind; Needham, Shane; Caturla, Maria Cruz; Steffen, Ray; Sheldon, Curtis; Hayes, Roger; Samuels, Tim; Di Donato, Lorella; Kamerud, John; Michael, Steve; Lin, Zhongping John; Hillier, Jim; Moussallie, Marc; de Souza Teixeira, Leonardo; Rocci, Mario; Buonarati, Mike; Truog, James; Hussain, Saleh; Lundberg, Richard; Breau, Alan; Zhang, Tianyi; Jonker, Jianine; Berger, Neil; Gagnon-Carignan, Sofi; Nehls, Corey; Nicholson, Robert; Hilhorst, Martijn; Karnik, Shane; de Boer, Theo; Houghton, Richard; Smith, Kirk; Cojocaru, Laura; Allen, Mike; Harter, Tammy; Fatmi, Saadya; Sayyarpour, Farhad; Vija, Jenifer; Malone, Michele; Heller, Dennis
2011-06-01
"The Global CRO Council (GCC) for Bioanalysis was formed in an effort to bring together many CRO leaders to openly discuss bioanalysis and the regulatory challenges unique to the outsourcing industry"
Lowes, Steve; Jersey, Jim; Shoup, Ronald; Garofolo, Fabio; Needham, Shane; Couerbe, Philippe; Lansing, Tim; Bhatti, Masood; Sheldon, Curtis; Hayes, Roger; Islam, Rafiq; Lin, Zhongping; Garofolo, Wei; Moussallie, Marc; Teixeira, Leonardo de Souza; Rocha, Thais; Jardieu, Paula; Truog, James; Lin, Jenny; Lundberg, Richard; Breau, Alan; Dilger, Carmen; Bouhajib, Mohammed; Levesque, Ann; Gagnon-Carignan, Sofi; Jenkins, Rand; Nicholson, Robert; Lin, Ming Hung; Karnik, Shane; DeMaio, William; Smith, Kirk; Cojocaru, Laura; Allen, Mike; Fatmi, Saadya; Sayyarpour, Farhad; Malone, Michele; Fang, Xinping
2012-04-01
The Global CRO Council for Bioanalysis (GCC) was formed in September 2010. Since then, the representatives of the member companies come together periodically to openly discuss bioanalysis and the regulatory challenges unique to the outsourcing industry. The 4th GCC Closed Forum brought together experts from bioanalytical CROs to share and discuss recent issues in regulated bioanalysis, such as the impact of coadministered drugs on stability, some differences between European Medicines Agency and US FDA bioanalytical guidance documents and lessons learned following recent Untitled Letters. Recent 483s and agency findings, as well as issues on method carryover, were also part of the topics discussed.
Dong, Xin; Wang, Rui; Zhou, Xu; Li, Ping; Yang, Hua
2016-07-15
Traditional Chinese medicines (TCMs) are gaining more and more attentions all over the world. The focus of TCMs researches were gradually shifted from chemical research to the combination study of chemical and life sciences. However, obtaining precise information of TCMs process in vivo or in vitro is still a bottleneck in bioanalysis of TCMs for their chemical composition complexity. This paper reviewed the recent analytical methods especially mass spectrometry technology in the bioanalysis of TCMs, and data processing techniques in the qualitative and quantitative analyses of metabolite of TCMs. Additionally, the difficulties encountered in the analyzing biological samples in TCMs and the solutions to these problems have been mentioned. Copyright © 2015 Elsevier B.V. All rights reserved.
Wang, Guang-Li; Yuan, Fang; Gu, Tiantian; Dong, Yuming; Wang, Qian; Zhao, Wei-Wei
2018-02-06
Herein we report a general and novel strategy for high-throughput photoelectrochemical (PEC) enzymatic bioanalysis on the basis of enzyme-initiated quinone-chitosan conjugation chemistry (QCCC). Specifically, the strategy was illustrated by using a model quinones-generating oxidase of tyrosinase (Tyr) to catalytically produce 1,2-bezoquinone or its derivative, which can easily and selectively be conjugated onto the surface of the chitosan deposited PbS/NiO/FTO photocathode via the QCCC. Upon illumination, the covalently attached quinones could act as electron acceptors of PbS quantum dots (QDs), improving the photocurrent generation and thus allowing the elegant probing of Tyr activity. Enzyme cascades, such as alkaline phosphatase (ALP)/Tyr and β-galactosidase (Gal)/Tyr, were further introduced into the system for the successful probing of the corresponding targets. This work features not only the first use of QCCC in PEC bioanalysis but also the separation of enzymatic reaction from the photoelectrode as well as the direct signal recording in a split-type protocol, which enables quite convenient and high-throughput detection as compared to previous formats. More importantly, by using numerous other oxidoreductases that involve quinones as reactants/products, this protocol could serve as a common basis for the development of a new class of QCCC-based PEC enzymatic bioanalysis and further extended for general enzyme-labeled PEC bioanalysis of versatile targets.
How much separation for LC-MS/MS quantitative bioanalysis of drugs and metabolites?
Tan, Aimin; Fanaras, John C
2018-05-01
LC-MS/MS has been the dominant analytical technology for quantitative bioanalysis of drugs and metabolites for more than two decades. Despite this, a very fundamental question like how much separation is required for LC-MS/MS quantitative bioanalysis of drugs and metabolites has not been adequately addressed. Some think that no or only very limited separation is necessary thanks to the unparalleled selectivity offered by tandem mass spectrometry. Others think that the more separation, the better, because of the potential detrimental impact of matrix effect (ion suppression or enhancement). Still others just use a rule-of-thumb approach by keeping the adjusted retention/capacity factor always between 2 and 5. The purpose of this article is to address this fundamental question through rational thinking together with various real case examples drawn from regulated bioanalytical laboratories. Copyright © 2018 Elsevier B.V. All rights reserved.
Energy Technology Data Exchange (ETDEWEB)
Yuan, Long, E-mail: long.yuan@bms.com [Bioanalytical Sciences, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States); Ma, Li [Biotransformation, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States); Dillon, Lisa [Discovery Toxicology, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States); Fancher, R. Marcus; Sun, Huadong [Metabolism and Pharmacokinetics, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States); Zhu, Mingshe [Biotransformation, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States); Lehman-McKeeman, Lois [Discovery Toxicology, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States); Aubry, Anne-Françoise [Bioanalytical Sciences, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States); Ji, Qin C., E-mail: qin.ji@bms.com [Bioanalytical Sciences, Research & Development, Bristol-Myers Squibb, Princeton, NJ 08543 (United States)
2016-11-16
LC-MS/MS has been widely applied to the quantitative analysis of tissue samples. However, one key remaining issue is that the extraction recovery of analyte from spiked tissue calibration standard and quality control samples (QCs) may not accurately represent the “true” recovery of analyte from incurred tissue samples. This may affect the accuracy of LC-MS/MS tissue bioanalysis. Here, we investigated whether the recovery determined using tissue QCs by LC-MS/MS can accurately represent the “true” recovery from incurred tissue samples using two model compounds: BMS-986104, a S1P{sub 1} receptor modulator drug candidate, and its phosphate metabolite, BMS-986104-P. We first developed a novel acid and surfactant assisted protein precipitation method for the extraction of BMS-986104 and BMS-986104-P from rat tissues, and determined their recoveries using tissue QCs by LC-MS/MS. We then used radioactive incurred samples from rats dosed with {sup 3}H-labeled BMS-986104 to determine the absolute total radioactivity recovery in six different tissues. The recoveries determined using tissue QCs and incurred samples matched with each other very well. The results demonstrated that, in this assay, tissue QCs accurately represented the incurred tissue samples to determine the “true” recovery, and LC-MS/MS assay was accurate for tissue bioanalysis. Another aspect we investigated is how the tissue QCs should be prepared to better represent the incurred tissue samples. We compared two different QC preparation methods (analyte spiked in tissue homogenates or in intact tissues) and demonstrated that the two methods had no significant difference when a good sample preparation was in place. The developed assay showed excellent accuracy and precision, and was successfully applied to the quantitative determination of BMS-986104 and BMS-986104-P in tissues in a rat toxicology study. - Highlights: • Investigated the “true” recovery in six different tissues using incurred
International Nuclear Information System (INIS)
Yuan, Long; Ma, Li; Dillon, Lisa; Fancher, R. Marcus; Sun, Huadong; Zhu, Mingshe; Lehman-McKeeman, Lois; Aubry, Anne-Françoise; Ji, Qin C.
2016-01-01
LC-MS/MS has been widely applied to the quantitative analysis of tissue samples. However, one key remaining issue is that the extraction recovery of analyte from spiked tissue calibration standard and quality control samples (QCs) may not accurately represent the “true” recovery of analyte from incurred tissue samples. This may affect the accuracy of LC-MS/MS tissue bioanalysis. Here, we investigated whether the recovery determined using tissue QCs by LC-MS/MS can accurately represent the “true” recovery from incurred tissue samples using two model compounds: BMS-986104, a S1P 1 receptor modulator drug candidate, and its phosphate metabolite, BMS-986104-P. We first developed a novel acid and surfactant assisted protein precipitation method for the extraction of BMS-986104 and BMS-986104-P from rat tissues, and determined their recoveries using tissue QCs by LC-MS/MS. We then used radioactive incurred samples from rats dosed with 3 H-labeled BMS-986104 to determine the absolute total radioactivity recovery in six different tissues. The recoveries determined using tissue QCs and incurred samples matched with each other very well. The results demonstrated that, in this assay, tissue QCs accurately represented the incurred tissue samples to determine the “true” recovery, and LC-MS/MS assay was accurate for tissue bioanalysis. Another aspect we investigated is how the tissue QCs should be prepared to better represent the incurred tissue samples. We compared two different QC preparation methods (analyte spiked in tissue homogenates or in intact tissues) and demonstrated that the two methods had no significant difference when a good sample preparation was in place. The developed assay showed excellent accuracy and precision, and was successfully applied to the quantitative determination of BMS-986104 and BMS-986104-P in tissues in a rat toxicology study. - Highlights: • Investigated the “true” recovery in six different tissues using incurred tissue
Baghdady, Yehia Z; Schug, Kevin A
2016-01-01
Accurate and specific analysis of target molecules in complex biological matrices remains a significant challenge, especially when ultra-trace detection limits are required. Liquid chromatography with mass spectrometry is often the method of choice for bioanalysis. Conventional sample preparation and clean-up methods prior to the analysis of biological fluids such as liquid-liquid extraction, solid-phase extraction, or protein precipitation are time-consuming, tedious, and can negatively affect target recovery and detection sensitivity. An alternative or complementary strategy is the use of an off-line or on-line in situ derivatization technique. In situ derivatization can be incorporated to directly derivatize target analytes in their native biological matrices, without any prior sample clean-up methods, to substitute or even enhance the extraction and preconcentration efficiency of these traditional sample preparation methods. Designed appropriately, it can reduce the number of sample preparation steps necessary prior to analysis. Moreover, in situ derivatization can be used to enhance the performance of the developed liquid chromatography with mass spectrometry-based bioanalysis methods regarding stability, chromatographic separation, selectivity, and ionization efficiency. This review presents an overview of the commonly used in situ derivatization techniques coupled to liquid chromatography with mass spectrometry-based bioanalysis to guide and to stimulate future research. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
YOUNG INVESTIGATOR SPECIAL ISSUE (Editorial
Directory of Open Access Journals (Sweden)
Eric Eils
2004-11-01
Full Text Available Welcome to the first Young Investigator Special Issue of the Journal of Sports Science and Medicine (JSSM. The JSSM family is proud to start this new service to the Sport Science community and to young researchers. The background in starting this issue was the observation that large amounts of high-quality research is conducted every year by students and young investigators, but often remains solely in local university libraries and never reaches the scientific community or databases. In addition, most international journals have a high threshold in accepting papers, and it is often hard to reach this level for junior scientists because of lack of experience, supervision or confidence. These are major reasons that delay or in some cases stop young researchers from publishing their valuable work. We all received help from senior colleagues in the beginning of our career. Now it is our turn to help youngsters. With this special issue, the JSSM is now serving young researchers as a channel for publishing their work. Our goal is to motivate young researchers to submit their work to JSSM, but we also aim to motivate supervisors and expert referees to be supportive and constructive towards these young scientists at the very beginning of their career. The Young Investigator Special Issue followed a normal peer-review process, except that there were no straight rejections in the first phase of review. We advised the reviewers of the Young Investigator Special Issue to proceed with constructive advice and remarks for all manuscripts. This offered a great opportunity for the Young Investigators to revise the manuscript, while at the same time contributing to the learning process. Thereafter, if the revisions were properly conducted according to the remarks from reviewers, the manuscripts were accepted for publication. We have received many manuscripts from young researchers with a lot of potential. There has been plenty of evidence of great talent
Implementation of an electronic laboratory notebook to accelerate data review in bioanalysis.
Shoup, Ronald E; Beato, Brian D; Pisek, April; White, Jessica; Branstrator, Laurel; Bousum, Abby; Roach, Jasmine; Grever, Tim
2013-07-01
Electronic laboratory notebooks increase opportunities for collaboration and information exchange when compared with paper records. Depending on the degree of implementation, a laboratory- or enterprise-wide system can unify the collection, review and dissemination of data to improve laboratory efficiency and productivity. The advantages of an electronic laboratory notebook for speeding data review in bioanalysis are discussed, through the use of validated templates and organizational constructs to block errors in real-time and reduce manual audit tasks.
Garner, C.R.; Park, K.B.; French, N.S.; Earnshaw, C.; Schipani, A.; Selby, A.M.; Byrne, L.; Siner, S.; Crawley, F.P.; Vaes, W.H.J.; Duijn, E. van; ligt, R. de; Varendi, H.; Lass, J.; Grynkiewicz, G.; Maruszak, W.; Turner, M.A.
2015-01-01
Aims The aims of the study were to compare [14C]-paracetamol ([14C]-PARA) paediatric pharmacokinetics (PK) after administration mixed in a therapeutic dose or an isolated microdose and to develop further and validate accelerator mass spectrometry (AMS) bioanalysis in the 0-2 year old age group.
Zhang, Ling; Sun, Yue; Liang, Yan-Yu; He, Jian-Ping; Zhao, Wei-Wei; Xu, Jing-Juan; Chen, Hong-Yuan
2016-11-15
Herein the influence of ultrasmall Ag nanoclusters (Ag NCs) against CdS quantum dots (QDs) in a photoelectrochemical (PEC) nanosystem was exploited for the first time, based on which a novel PEC bioanalysis was successfully developed via the efficient quenching effect of Ag NCs against the CdS QDs. In a model system, DNA assay was achieved by using molecular beacon (MB) probes anchored on a CdS QDs modified electrode, and the MB probes contain two segments that can hybridize with both target DNA sequence and the label of DNA encapsulated Ag NCs. After the MB probe was unfolded by the target DNA sequence, the labels of oligonucleotide encapsulated Ag NCs would be brought in close proximity to the CdS QDs electrode surface, and efficient photocurrent quenching of QDs could be resulted from an energy transfer process that originated from NCs. Thus, by monitoring the attenuation in the photocurrent signal, an elegant and sensitive PEC DNA bioanalysis could be accomplished. The developed biosensor displayed a linear range from 1.0pM to 10nM and the detection limit was experimentally found to be of 0.3pM. This work presents a feasible signaling principle that could act as a common basis for general PEC bioanalysis development. Copyright © 2016 Elsevier B.V. All rights reserved.
De Vooght-Johnson, Ryan
2011-03-01
An evening symposium was held at the Museu de Historia de Catalunya (Barcelona, Spain) as a precursor to the European Bioanalysis Forum meeting, as part of the Waters Corporation Bioanalysis World Tour. The symposium was chaired by Robert Plumb and Jing Lin (Waters Corporation, MA, USA) with a focus on the future of the DMPK laboratory and its role in addressing large-molecule therapeutics and biomarkers. Lieve Dillen (Johnson and Johnson, Belgium) spoke on ultra-sensitive peptide quantification, Richard Kay (Quotient Bioresearch, UK) discussed quantifying proteins and peptides in plasma, Ian Wilson (AstraZeneca, UK) covered metabolic biomarkers and Robert Plumb concluded the evening with a presentation on the future of MS in DMPK studies. Following the presentations, all the speakers took questions from the audience and continued lively discussion over a cocktails and canapés reception.
International Nuclear Information System (INIS)
Miyaoka, Teiji; Isono, Yoshimi; Setani, Kaoru; Sakai, Kumiko; Yamada, Ichimaro; Sato, Yoshiaki; Gunji, Shinobu; Matsui, Takao
2007-01-01
Institute of Accelerator Analysis Ltd. (IAA) is the first Contract Research Organization in Japan providing Accelerator Mass Spectrometry (AMS) analysis services for carbon dating and bioanalysis works. The 3 MV AMS machines are maintained by validated analysis methods using multiple control compounds. It is confirmed that these AMS systems have reliabilities and sensitivities enough for each objective. The graphitization of samples for bioanalysis is prepared by our own purification lines including the measurement of total carbon content in the sample automatically. In this paper, we present the use of AMS analysis in human mass balance and metabolism profiling studies with IAA 3 MV AMS, comparing results obtained from the same samples with liquid scintillation counting (LSC). Human samples such as plasma, urine and feces were obtained from four healthy volunteers orally administered a 14 C-labeled drug Y-700, a novel xanthine oxidase inhibitor, of which radioactivity was about 3 MBq (85 μCi). For AMS measurement, these samples were diluted 100-10,000-fold with pure-water or blank samples. The results indicated that AMS method had a good correlation with LSC method (e.g. plasma: r = 0.998, urine: r = 0.997, feces: r = 0.997), and that the drug recovery in the excreta exceeded 92%. The metabolite profiles of plasma, urine and feces obtained with HPLC-AMS corresponded to radio-HPLC results measured at much higher radioactivity level. These results revealed that AMS analysis at IAA is useful to measure 14 C-concentration in bioanalysis studies at very low radioactivity level
Recent advances in column switching sample preparation in bioanalysis.
Kataoka, Hiroyuki; Saito, Keita
2012-04-01
Column switching techniques, using two or more stationary phase columns, are useful for trace enrichment and online automated sample preparation. Target fractions from the first column are transferred online to a second column with different properties for further separation. Column switching techniques can be used to determine the analytes in a complex matrix by direct sample injection or by simple sample treatment. Online column switching sample preparation is usually performed in combination with HPLC or capillary electrophoresis. SPE or turbulent flow chromatography using a cartridge column and in-tube solid-phase microextraction using a capillary column have been developed for convenient column switching sample preparation. Furthermore, various micro-/nano-sample preparation devices using new polymer-coating materials have been developed to improve extraction efficiency. This review describes current developments and future trends in novel column switching sample preparation in bioanalysis, focusing on innovative column switching techniques using new extraction devices and materials.
The science of laboratory and project management in regulated bioanalysis.
Unger, Steve; Lloyd, Thomas; Tan, Melvin; Hou, Jingguo; Wells, Edward
2014-05-01
Pharmaceutical drug development is a complex and lengthy process, requiring excellent project and laboratory management skills. Bioanalysis anchors drug safety and efficacy with systemic and site of action exposures. Development of scientific talent and a willingness to innovate or adopt new technology is essential. Taking unnecessary risks, however, should be avoided. Scientists must strategically assess all risks and find means to minimize or negate them. Laboratory Managers must keep abreast of ever-changing technology. Investments in instrumentation and laboratory design are critical catalysts to efficiency and safety. Matrix management requires regular communication between Project Managers and Laboratory Managers. When properly executed, it aligns the best resources at the right times for a successful outcome. Attention to detail is a critical aspect that separates excellent laboratories. Each assay is unique and requires attention in its development, validation and execution. Methods, training and facilities are the foundation of a bioanalytical laboratory.
Arfvidsson, Cecilia; Severin, Paul; Holmes, Victoria; Mitchell, Richard; Bailey, Christopher; Cape, Stephanie; Li, Yan; Harter, Tammy
2017-08-01
The AstraZeneca and Covance Laboratories Clinical Bioanalysis Alliance (CBioA) was launched in 2011 after a period of global economic recession. In this challenging environment, AstraZeneca elected to move to a full and centralized outsourcing model that could optimize the number of people supporting bioanalytical work and reduce the analytical cost. This paper describes the key aspects of CBioA, the innovative operational model implemented, and our ways of ensuring this was much more than simply a cost reduction exercise. As we have recently passed the first 5-year cycle, this paper also summarizes some of the concluding benefits, wins and lessons learned, and how we now plan to extend and develop the relationship even further moving into a new clinical laboratory partnership.
New materials for sample preparation techniques in bioanalysis.
Nazario, Carlos Eduardo Domingues; Fumes, Bruno Henrique; da Silva, Meire Ribeiro; Lanças, Fernando Mauro
2017-02-01
The analysis of biological samples is a complex and difficult task owing to two basic and complementary issues: the high complexity of most biological matrices and the need to determine minute quantities of active substances and contaminants in such complex sample. To succeed in this endeavor samples are usually subject to three steps of a comprehensive analytical methodological approach: sample preparation, analytes isolation (usually utilizing a chromatographic technique) and qualitative/quantitative analysis (usually with the aid of mass spectrometric tools). Owing to the complex nature of bio-samples, and the very low concentration of the target analytes to be determined, selective sample preparation techniques is mandatory in order to overcome the difficulties imposed by these two constraints. During the last decade new chemical synthesis approaches has been developed and optimized, such as sol-gel and molecularly imprinting technologies, allowing the preparation of novel materials for sample preparation including graphene and derivatives, magnetic materials, ionic liquids, molecularly imprinted polymers, and much more. In this contribution we will review these novel techniques and materials, as well as their application to the bioanalysis niche. Copyright © 2016 Elsevier B.V. All rights reserved.
Directory of Open Access Journals (Sweden)
Xiaoli Qin
2016-08-01
Full Text Available We report a protocol of CdS-labeled sandwich-type amperometric bioanalysis with high sensitivity, on the basis of simultaneous chemical-dissolution/cathodic-enrichment of the CdS quantum dot biolabel and anodic stripping voltammetry (ASV detection of Cd directly on the bioelectrode. We added a microliter droplet of 0.1 M aqueous HNO3 to dissolve CdS on the bioelectrode and simultaneously achieved the potentiostatic cathodic preconcentration of Cd by starting the potentiostatic operation before HNO3 addition, which can largely increase the ASV signal. Our protocol was used for immunoanalysis and aptamer-based bioanalysis of several proteins, giving limits of detection of 4.5 fg·mL−1 for human immunoglobulin G, 3.0 fg·mL−1 for human carcinoembryonic antigen (CEA, 4.9 fg·mL−1 for human α-fetoprotein (AFP, and 0.9 fM for thrombin, which are better than many reported results. The simultaneous and sensitive analysis of CEA and AFP at two screen-printed carbon electrodes was also conducted by our protocol.
Kellie, John F; Kehler, Jonathan R; Karlinsey, Molly Z; Summerfield, Scott G
2017-12-01
Typically, quantitation of biotherapeutics from biological matrices by LC-MS is based on a surrogate peptide approach to determine molecule concentration. Recent efforts have focused on quantitation of the intact protein molecules or larger mass subunits of monoclonal antibodies. To date, there has been limited guidance for large or intact protein mass quantitation for quantitative bioanalysis. Intact- and subunit-level analyses of biotherapeutics from biological matrices are performed at 12-25 kDa mass range with quantitation data presented. Linearity, bias and other metrics are presented along with recommendations made on the viability of existing quantitation approaches. This communication is intended to start a discussion around intact protein data analysis and processing, recognizing that other published contributions will be required.
Abstracts of European Young Investigator Conference 2005
International Nuclear Information System (INIS)
2005-01-01
The conference specially aim at the active participation of all European young investigators, typically consisting of graduate students and postdocs below the age of 35. All participants share an interest in free radical chemistry, radiation chemistry and physics, photochemistry, radiobiology, life sciences and environmentally related topics that cover experimental and theoretical aspects
Crisino, Rebecca M; Geist, Brian; Li, Jian
2012-09-01
The American Association of Pharmaceutical Scientists (AAPS) is an international forum for the exchange of knowledge among scientists to enhance their contributions to drug development. The annual National Biotechnology Conference, organized by the AAPS on 21-23 May 2012 in San Diego, CA, USA, brings together experts from various disciplines representing private industry, academia and governing institutions dedicated toward advancing the scientific and technological progress related to discovery, development and manufacture of medical biotechnology products. Over 300 scientific poster presentations and approximately 50 oral presentation and discussion sessions examined a breadth of topics pertaining to biotechnology drug development, such as the advancement of vaccines and biosimilars, emerging and innovative technologies, nonclinical and clinical bioanalysis, and regulatory updates. This conference report highlights the existing challenges with ligand-binding assays, emerging challenges, innovative integration of various technology platforms and applicable regulatory considerations as they relate to immunogenicity and pharmacokinetic bioanalytical assessments.
Energy Technology Data Exchange (ETDEWEB)
Xu, Aoshuang [Iowa State Univ., Ames, IA (United States)
2008-01-01
This dissertation begins with a general introduction of topics related to this work. The following chapters contain three scientific manuscripts, each presented in a separate chapter with accompanying tables, figures, and literature citations. The final chapter summarizes the work and provides some prospective on this work. This introduction starts with a brief treatment of the basic principles of electrophoresis separation, followed by a discussion of gel electrophoresis and particularly polyacrylamide gel electrophoresis for protein separation, a summary of common capillary electrophoresis separation modes, and a brief treatment of micro-bioanalysis application of capillary electrophoresis, and ends with an overview of protein conformation and dynamics.
1st European Biomedical Engineering Conference for Young Investigators
2015-01-01
This volume presents the proceedings of the first European Biomedical Engineering Conference for Young Investigators ENCY2015. It was in Budapest, from 28th to 30th May, 2015. The papers were assembled under the motto "Understanding complex living systems” and cover the topics sensors, image processing, bioinformatics, biomechanics, and modeling.
Bioanalysis: its past, present, and some future.
Righetti, Pier Giorgio
2004-07-01
An overview of about 100 years of bioanalysis is here disastrously attempted. The beginning of rigorous analytical systems can perhaps be traced back to the building and testing of the analytical ultracentrifuge by Svedberg and the apparatus for moving-boundary electrophoresis of Tiselius, both systems relying on expensive and hard to operate machines. In the sixties, Porath discovered porous beads for the determination of relative molecular mass (Mr) of proteins, based on the principle of molecular sieving. Concomitantly, Svensson and his pupil Vesterberg described a revolutionary principle for fractionating proteins in a nonisocratic environment, based on generation of stable pH gradients in an electric field, a technique that went down to history as isoelectric focusing (IEF). Polyacrylamide gel electrophoresis (PAGE), with the brilliant idea of discontinuous buffers, was brought to the limelight and in 1967, sodium dodecyl sulfate (SDS)-PAGE was described, permitting easy assessment of protein purity and reasonable measurements of Mr values of denatured polypeptide chains. By the mid seventies, another explosive concept was realized: orthogonal combination of two unrelated techniques, based on surface charge and mass fractionation, namely, two-dimensional (2-D) PAGE already in the very first papers by O'Farrell elaborated to its utmost sophistication. The eighties saw the systematic growth of 2-D PAGE, accompanied by systematic efforts to develop instrumentation for large-scale production of 2-D maps and computer evaluation for 2-D map analysis, based on the sophisticated algorithms adopted by astronomers for mapping stars in the sky. Another fundamental innovation in the field of IEF was the discovery of immobilized pH gradients (IPGs) that brought the much needed reproducibility in 2-D maps while allowing exquisite resolution in very narrow pH ranges. The nineties were definitely the decade of capillary zone electrophoresis, with the concomitant concept of
Luckwell, Jacquelynn; Denniff, Philip; Capper, Stephen; Michael, Paul; Spooner, Neil; Mallender, Philip; Johnson, Barry; Clegg, Sarah; Green, Mark; Ahmad, Sheelan; Woodford, Lynsey
2013-11-01
To ensure that PK data generated from DBS samples are of the highest quality, it is important that the paper substrate is uniform and does not unduly contribute to variability. This study investigated any within and between lot variations for four cellulose paper types: Whatman™ FTA(®) DMPK-A, -B and -C, and 903(®) (GE Healthcare, Buckinghamshire, UK). The substrates were tested to demonstrate manufacturing reproducibility (thickness, weight, chemical coating concentration) and its effect on the size of the DBS produced, and the quantitative data derived from the bioanalysis of human DBS samples containing six compounds of varying physicochemical properties. Within and between lot variations in paper thickness, mass and chemical coating concentration were within acceptable manufacturing limits. No variation in the spot size or bioanalytical data was observed. Bioanalytical results obtained for DBS samples containing a number of analytes spanning a range of chemical space are not affected by the lot used or by the location within a lot.
An investigation toward the perception of young Taiwanese consumers’ fashion consumption behaviour
WEN, YEN-HSUAN
2014-01-01
Given an increasingly competitive fashion environment, several multinational corporations have shown their tendency to enter Taiwan’s fashion market. Young Taiwanese consumers seem more than willing to embrace these foreign brands. The purpose of this research is to investigate young Taiwanese consumers’ fashion apparel consumption behaviour, including their evaluations toward “country of origin” effect and to discover their preference of foreign brands; in addition, to explore the issue o...
Chemometric investigation of the volatile content of young South African wines
Weldegergis, B.T.; Villiers, de A.; Crouch, A.M.
2011-01-01
The content of major volatiles of 334 wines of six different cultivars (Sauvignon Blanc, Chardonnay, Pinotage, Shiraz, Cabernet Sauvignon and Merlot) and vintage 2005 was used to investigate the aroma content of young South African wines. Wines were sourced from six different regions and various
Mottillo, Salvatore; Boyle, Pierre; Jacobi Cadete, Lindsay D.; Rouleau, Jean-Lucien; Eisenberg, Mark J.
2016-01-01
Background. Improving mentorship may help decrease the shortage of young investigators (graduate students, postdoctoral fellows, and new investigators) available to work as independent researchers in cardiovascular and respiratory health. Objectives. To determine (1) the mentoring practices for trainees affiliated with the Canadian Institutes of Health Research (CIHR), Institute of Circulatory and Respiratory Health (ICRH), (2) the positive attributes of mentors, and (3) the recommendations regarding what makes good mentorship. Methods. We conducted a survey and descriptive analysis of young investigators with a CIHR Training and Salary Award from 2010 to 2013 or who submitted an abstract to the ICRH 2014 Young Investigators Forum. Clinicians were compared to nonclinicians. Results. Of 172 participants, 7.0% had no mentor. Only 43.6% had defined goals and 40.7% had defined timelines, while 54.1% had informal forms of mentorship. A significant proportion (33.1%) felt that their current mentorship did not meet their needs. Among clinicians, 22.2% would not have chosen the same mentor again versus 11.4% of nonclinicians. All participants favored mentors who provided guidance on career and work-life balance. Suggestions for improved mentoring included formal mentorship, increased networking, and quality assurance. Conclusion. There is an important need to improve mentoring in cardiovascular and respiratory health. PMID:27445544
Directory of Open Access Journals (Sweden)
Salvatore Mottillo
2016-01-01
Full Text Available Background. Improving mentorship may help decrease the shortage of young investigators (graduate students, postdoctoral fellows, and new investigators available to work as independent researchers in cardiovascular and respiratory health. Objectives. To determine (1 the mentoring practices for trainees affiliated with the Canadian Institutes of Health Research (CIHR, Institute of Circulatory and Respiratory Health (ICRH, (2 the positive attributes of mentors, and (3 the recommendations regarding what makes good mentorship. Methods. We conducted a survey and descriptive analysis of young investigators with a CIHR Training and Salary Award from 2010 to 2013 or who submitted an abstract to the ICRH 2014 Young Investigators Forum. Clinicians were compared to nonclinicians. Results. Of 172 participants, 7.0% had no mentor. Only 43.6% had defined goals and 40.7% had defined timelines, while 54.1% had informal forms of mentorship. A significant proportion (33.1% felt that their current mentorship did not meet their needs. Among clinicians, 22.2% would not have chosen the same mentor again versus 11.4% of nonclinicians. All participants favored mentors who provided guidance on career and work-life balance. Suggestions for improved mentoring included formal mentorship, increased networking, and quality assurance. Conclusion. There is an important need to improve mentoring in cardiovascular and respiratory health.
Investigating Young Consumers’ Purchasing Intention of Green Housing in China
Directory of Open Access Journals (Sweden)
Lin Zhang
2018-04-01
Full Text Available The issues of energy crisis, environmental degradation, and climate change present a severe challenge to the sustainable development in China. The development of green building (GB is considered one of the most popular strategies toward a sustainable construction industry. Apart from advanced green technologies, consumers’ purchasing intention toward green housing (GH plays a crucial role in the large-scale promotion of GB. However, which determinants significantly affect consumers’ purchasing intention remain unclear, especially for the young generation in developing countries. This study attempts to investigate young consumers’ purchasing intention of GH in China. On the basis of extended theory of planned behavior (TPB, seven constructs are identified, and nine hypotheses are proposed. A total of 241 responses were collected from the questionnaire survey, and structural equation modeling was employed to test the proposed hypotheses. Governmental incentives are affirmed to be the most important determinant, followed by consumers’ attitude toward behavior and subjective norm. Perceived behavioral control is an insignificant determinant for young consumers to purchase GH. In addition, subjective knowledge has an indirect effect through attitude toward behavior. Environmental concern also confirms an indirect effect through attitude toward behavior and subjective norm toward purchasing intention, respectively. Thus, the government is implied to play a crucial role in GH promotion at this stage.
Carroll, Catherine
2015-01-01
Investigations into the lives and transition from compulsory schooling of young adults with a disability, including a learning difficulty (LD), are increasing. The emerging consensus is one which points to this group of young people experiencing greater difficulties and poorer outcomes compared to the general population. How these investigations…
Li, Zheng; Han, Jie; Sun, Shi-an; Chen, Kai; Tang, Dao-quan
2016-01-01
During the development, dosage optimization and safety evaluation of a drug, rapid and precise monitoring of administered drug and/or its metabolites in biological samples including blood, plasma, serum, tissues and saliva are vital. As drug biotransformation produces more hydrophilic metabolites for the enhancement of drug elimination, which is often a challenge for traditional reversed-phase liquid chromatography (RPLC) separation. Because hydrophilic interaction liquid chromatography (HILIC) is capable of retaining polar compounds and readily compatible with mass spectrometry (MS), HILIC has been used as a complementary separation technique to RPLC for analysis of polar metabolites, especially polar drugs and their metabolites. This review covers core aspects of HILIC-MS/MS method and overall profile of its application in analysis of drug and/or its metabolites. The emphasis of this paper has been placed on the applications of HILIC-MS/MS method in quantitative bioanalysis of drugs alone or along with their metabolites in drug metabolism studies in recent years. As a fundamental and critical step of bioanalytical method, conventional sample preparation techniques of biological matrices for the HILIC-MS/MS analysis of drugs and/or their metabolites are also briefly featured.
Uno, Jennifer; Walton, Kristen L W
2014-05-01
This editorial continues with our Young Investigator Perspectives series. Drs. Uno and Walton are young investigators who hold faculty positions. They completed a K12 postdoctoral program through the IRACDA (Individual Research and Career Development Award) program sponsored through the NIGMS institute at NIH. IRACDA programs exist at multiple institutions in the USA to combine postdoctoral training with formal training in academic skills and teaching at partner institutions. I thank Drs. Walton and Uno for a thoughtful perspective on how this experience shaped their career goals to combine teaching and research and inspire undergraduates to science careers. Given the current national dialog on broadening career paths and outcomes for PhD scientists, this is a timely perspective. -P. Kay Lund.
Investigation of the Effects of Teaching Core Exerciseson Young Soccer Players
Yapici, Aysegül
2016-01-01
The objective of this study is to investigate the effects of teaching core exercises on some motoric parameters in young soccer players. 32 amateur male football players from Afjet Afyonspor and Muglaspor football team; 16 experimental group (average age 13.75 ± 0.46 years; mean body height 1.65.± 0.09 cm; mean body mass 52.88 ± 8.04 kg) and 16…
Konieczna, Lucyna; Pyszka, Magdalena; Okońska, Magdalena; Niedźwiecki, Maciej; Bączek, Tomasz
2018-03-23
Exhaled breath condensate (EBC) is receiving increased attention as a novel, entirely non-invasive technique for collecting biomarker samples. This increased attention is due to the fact that EBC is simple, effort independent, rapid, can be repeated frequently, and can be performed on young children and patients suffering from a variety of diseases. By having a subject breathe tidally through a cooling system for 15-20 min, a sufficient amount of condensate is collected for analysis of biomarkers in clinical studies. However, bioanalysis of EBC involves an unavoidable sample preparation step due to the low concentration of its components. Thus, there is a need for a new and more sensitive analytical method of assessing EBC samples. While researchers have considered analyses of single and small quantities of amino acids - for example, those connected with leukemia - no one has previously attempted to simultaneously analyze a panel of 23 amino acids. Moreover, the present study is well-justified, as prior studies focusing on single amino acids and leukemia at the moment of diagnosis and during chemotherapy (33 days of treatment) are inconsistent. In the present study, amino acids were separated using an XBridge Amide column (3 mm × 100 mm, 3.5 μm). The mobile phase consisted of 10 mM of ammonium buffer in water with a pH of 3 (Phase A) and 10 mM ammonium buffer in acetonitrile (Phase B) under gradient program elution. The analytes were detected in electrospray positive ionization mode. Under optimal conditions, the proposed method exhibited limits of quantification (LOQ) in the range of 0.05-0.5 ng/mL, and good linearity, with the determination coefficient (R 2 ) falling between 0.9904 and 0.9998. The accuracy in human exhaled breath condensate samples ranged between 93.3-113.3% for the 23 studied amino acids, with intra- and inter-day coefficient of variation (CVs) of 0.13-9.92% and 0.17-10.53%, respectively. To demonstrate the liquid
International Nuclear Information System (INIS)
Mueller, K.H.G.
1988-01-01
Using comparative investigations in micromorphometry and microradiograms of cross sections of the bone we got new results about the mineralisation of residual bridges of the cartilage and the neogenesis of the osteoid. In contrast to the current interpretation investigations in primary- or micro osteons as well in cross sections as in longitudinal sections of the bone show a periodic and inhomogeneous mineralisation during bone development in premature and young infants. (orig.) [de
Directory of Open Access Journals (Sweden)
Eric O. Freed
2015-02-01
Full Text Available With the goal of recognizing outstanding contributions to the field of virology by early-career investigators, last year Viruses accepted nominations for a 2015 Young Investigator Prize in Virology. The target age was set at 40 and under. Over 50 nominations were received and were evaluated by a panel of judges comprised of Viruses editorial board members.[...
International Nuclear Information System (INIS)
Holubova, Lucie; Knotek, Petr; Palarcik, Jiri; Cadkova, Michaela; Belina, Petr; Vlcek, Milan; Korecka, Lucie; Bilkova, Zuzana
2014-01-01
Iron oxide based particles functionalized by bioactive molecules have been utilized extensively in biotechnology and biomedicine. Despite their already proven advantages, instability under changing reaction conditions, non-specific sorption of biomolecules on the particles' surfaces, and iron oxide leakage from the naked particles can greatly limit their application. As confirmed many times, surface treatment with an appropriate stabilizer helps to minimize these disadvantages. In this work, we describe enhanced post-synthetic surface modification of superparamagnetic microparticles varying in materials and size using hyaluronic acid (HA) in various chain lengths. Scanning electron microscopy, atomic force microscopy, phase analysis light scattering and laser diffraction are the methods used for characterization of HA-coated particles. The zeta potential and thickness of HA-layer of HA-coated Dynabeads M270 Amine were − 50 mV and 85 nm, respectively, and of HA-coated p(GMA-MOEAA)-NH 2 were − 38 mV and 140 nm, respectively. The electrochemical analysis confirmed the zero leakage of magnetic material and no reactivity of particles with hydrogen peroxide. The rate of non-specific sorption of bovine serum albumin was reduced up to 50% of the naked ones. The coating efficiency and suitability of biopolymer-based microparticles for magnetically active microfluidic devices were confirmed. - Highlights: • Post-synthetic surface modification of magnetic microparticles by hyaluronic acid • Hyaluronic acid — polymer of unique physicochemical and biological characteristics • Panel of particle characterization methods was introduced. • HA-coated microparticles gain characteristics suited for microfluidic bioanalysis
International Nuclear Information System (INIS)
Lu, Dingjie; Xie, Yi Min; Huang, Xiaodong; Zhou, Shiwei; Li, Qing
2015-01-01
Analytical studies on the size effects of a simply-shaped beam fixed at both ends have successfully explained the sudden changes of effective Young's modulus as its diameter decreases below 100 nm. Yet they are invalid for complex nanostructures ubiquitously existing in nature. In accordance with a generalized Young-Laplace equation, one of the representative size effects is transferred to non-uniformly distributed pressure against an external surface due to the imbalance of inward and outward loads. Because the magnitude of pressure depends on the principal curvatures, iterative steps have to be adopted to gradually stabilize the structure in finite element analysis. Computational results are in good agreement with both experiment data and theoretical prediction. Furthermore, the investigation on strengthened and softened Young's modulus for two complex nanostructures demonstrates that the proposed computational method provides a general and effective approach to analyze the size effects for nanostructures in arbitrary shape
Adamczyk, Katarzyna
2016-01-01
The present study tested the hypothesis that single young adults who perceive their singlehood as voluntary would report a higher level of positive mental health (i.e., emotional, psychological and social well-being), lower levels of mental health illness (i.e., somatic symptoms, anxiety, social dysfunction, severe depression) and romantic loneliness in comparison to young adults who perceive their singlehood as involuntary. This paper also investigated whether romantic loneliness mediates th...
Methodology for quantification of radionuclides used in therapy by bioanalysis 'in vitro'
International Nuclear Information System (INIS)
Juliao, Ligia M.Q.C.; Sousa, Wanderson O.; Mesquita, Sueli A.; Santos, Maristela S.; Oliveira, S.M. Velasques de
2008-01-01
In Brazil, the radionuclides used for therapy are 131 ; 153 Sm, 90 Y and 177 Lu, under routine or experimentally. The quantification of the radiopharmaceutical activity excreted by the patient through the bioassay method, can be an important tool for individualized dosimetry, aiming the planning of subsequent therapies. The Bioanalysis In Vitro Laboratory (LBIOVT) of the Service of Individual monitoring (SEMIN) of the Institute for Radiation Protection and Dosimetry (IRD/CNEN-RJ), Brazil, has equipment and procedures for gamma and beta spectrometry. These detection systems are calibrated in energy and efficiency, and used standard reference sources provided by the National Laboratory of Metrology of Ionizing Radiation (LMNRI/IRD/CNEN-RJ). The LBIOVT Quality System follows the guidelines of the ISO-ABNT-17025 standard and annually, the laboratory participates in national (PNI) and international (PROCORAD). With respect to the excreta samples from patients, these are collected immediately after administration of the radiopharmaceutical. During the first 24 hours, they are collected with the patient hospitalized, and depending upon the physical half-life of the radionuclide can also be collected in the patient's home. Both in hospital and at home, the excreta is handled, stored and transported in accordance with standards for clinical research, radiation protection and transport of radioactive and biological materials. The specific activity radionuclide is referenced to the date and time of collection, allowing further evaluation of biological individual half-life. The care with the registration of excreted volumes as well as possible loss of excreta during collection, may interfere with the interpretation of the measures, since the results are provided in specific activity (Bq / L). Regarding the bioassay laboratory, these results are reliable when the laboratory is certified and participates in intercomparison programs of measures and methods. The laboratory
Hoek, Janet; Tautolo, El Shadan; Gifford, Heather
2017-01-01
Objectives Reducing smoking in young adults, particularly young Māori and Pacific, is vital for reducing tobacco harm and health inequalities in New Zealand (NZ). We investigated how NZ policy experts appraised the feasibility and likely effectiveness of interventions designed to reduce smoking prevalence among 18–24 year olds. Design We used a qualitative design, conducting semistructured interviews and applying thematic analysis. Participants We interviewed 15 key informants, including politicians, senior policy analysts and leading tobacco control advocates. Participant selection was based on seniority and expertise and ensuring diverse perspectives were represented. Interventions We examined nine interventions that could either promote greater mindfulness or introduce barriers impeding smoking uptake: smoke-free outdoor dining and bars; no tobacco sales where alcohol is sold; social marketing campaigns; real life stories (testimonials); life skills training; raise purchase age to 21; tobacco-free generation; smokers’ licence; make tobacco retail premises R18. Results The policies perceived as more effective denormalised tobacco; made it less convenient to access and use; highlighted immediate disadvantages (eg, impact on fitness); aligned with young people’s values; and addressed the underlying causes of smoking (eg, stress). Participants highlighted some political barriers and noted concerns that some interventions might widen ethnic disparities. Exceptions were social marketing campaigns and extending smoke-free regulations to include outdoor areas of cafes and bars, which participants saw as politically feasible and likely to be effective. Conclusions Our findings suggest the merit of an approach that combines social marketing with regulation that makes accessing and using tobacco less convenient for young adults; however, political barriers may limit the regulatory options available in the short term. Strategies to support self-determination and
Wright, Michelle F; Li, Yan
2012-09-01
Using the general strain theory as a theoretical framework, the present longitudinal study investigated both face-to-face and cyber victimization in relation to cyber-displaced aggression. Longitudinal data were collected from 130 (70 women) young adults who completed measures assessing their victimization (face-to-face and cyber), cyber aggression, and both face-to-face and cyber-displaced aggression. Findings indicated that victimization in both social contexts (face-to-face and cyber) contributed to cyber-displaced aggression 6 months later (Time 2), after controlling for gender, cyber aggression, face-to-face displaced aggression, and cyber-displaced aggression at Time 1. A significant two-way interaction revealed that Time 1 cyber victimization was more strongly related to Time 2 cyber-displaced aggression when young adults had higher levels of face-to-face victimization at Time 1. Implications of these findings are discussed as well as a call for more research investigating displaced aggression in the cyber context.
Hovdestad, W; Shields, M; Williams, G; Tonmyr, L
2015-01-01
Young mothers' families are at increased risk of child maltreatment and other poor health and social outcomes. Chi-square analyses of pooled child welfare services data from the Canadian Incidence Study of Reported Child Abuse and Neglect (CIS-2003; CIS-2008) were used to compare 284 teen mothers (18 years or younger) and 800 young mothers (19-21 years) and their families with 5752 families where the mother was 22 years or older. Twenty-six percent of young mothers were 18 years or younger. Most (68% of teen-mother families and 57% of families with a young adult mother) received social assistance as their main source of income compared with 36% of families with a mother aged 22 years or older. Teen and young adult mothers were more likely than those aged 22 or older to have childhood histories of out-of-home care (31% and 23% vs. 10%) and were more likely to have risk factors such as alcohol abuse (25% and 23% vs. 18%) and few social supports (46% and 41% vs. 37%). Secondary caregivers in families with young mothers also had more risk factors. Teen and young adult mother families were more likely to have their child placed out-of-home during the investigation (29% and 27% vs. 17%). All were equally likely to be victims of domestic violence and to have mental health issues. Within this sample of high-risk families, young mothers' families were more at risk than comparison families. Mothers' youth may be a useful criterion to identify families for targeted interventions.
Young's moduli of carbon materials investigated by various classical molecular dynamics schemes
Gayk, Florian; Ehrens, Julian; Heitmann, Tjark; Vorndamme, Patrick; Mrugalla, Andreas; Schnack, Jürgen
2018-05-01
For many applications classical carbon potentials together with classical molecular dynamics are employed to calculate structures and physical properties of such carbon-based materials where quantum mechanical methods fail either due to the excessive size, irregular structure or long-time dynamics. Although such potentials, as for instance implemented in LAMMPS, yield reasonably accurate bond lengths and angles for several carbon materials such as graphene, it is not clear how accurate they are in terms of mechanical properties such as for instance Young's moduli. We performed large-scale classical molecular dynamics investigations of three carbon-based materials using the various potentials implemented in LAMMPS as well as the EDIP potential of Marks. We show how the Young's moduli vary with classical potentials and compare to experimental results. Since classical descriptions of carbon are bound to be approximations it is not astonishing that different realizations yield differing results. One should therefore carefully check for which observables a certain potential is suited. Our aim is to contribute to such a clarification.
Directory of Open Access Journals (Sweden)
W. Hovdestad
2015-01-01
Full Text Available Introduction: Young mothers' families are at increased risk of child maltreatment and other poor health and social outcomes. Methods: Chi-square analyses of pooled child welfare services data from the Canadian Incidence Study of Reported Child Abuse and Neglect (CIS-2003; CIS-2008 were used to compare 284 teen mothers (18 years or younger and 800 young mothers (19-21 years and their families with 5752 families where the mother was 22 years or older. Results: Twenty-six percent of young mothers were 18 years or younger. Most (68% of teen-mother families and 57% of families with a young adult mother received social assistance as their main source of income compared with 36% of families with a mother aged 22 years or older. Teen and young adult mothers were more likely than those aged 22 or older to have childhood histories of out-of-home care (31% and 23% vs. 10% and were more likely to have risk factors such as alcohol abuse (25% and 23% vs. 18% and few social supports (46% and 41% vs. 37%. Secondary caregivers in families with young mothers also had more risk factors. Teen and young adult mother families were more likely to have their child placed out-of-home during the investigation (29% and 27% vs. 17%. All were equally likely to be victims of domestic violence and to have mental health issues. Conclusion: Within this sample of high-risk families, young mothers' families were more at risk than comparison families. Mothers' youth may be a useful criterion to identify families for targeted interventions.
Gilliver, Megan; Beach, Elizabeth Francis; Williams, Warwick
2015-04-01
To investigate factors influencing young people's motivation to reduce their leisure noise exposure, and protect their hearing health. Questionnaires were conducted online to investigate young people's hearing health attitudes and behaviour. Items were developed using an integrated health promotion approach. The stage of change model was used to group participants in relation to their engagement with noise reduction behaviour. The health belief model was used to compare each group's perceptions of susceptibility and severity of hearing loss, as well as the benefits and barriers to noise reduction. Results are presented for 1196 young Australians aged between 18 and 35 years. Participants' engagement with noise reduction behaviour was used to assign them to stage of change groupings: Maintenance (11%), Action (28%), Contemplation (14%), or Pre-contemplation (43%). Each group's responses to health belief model items highlighted key differences across the different stages of engagement. Future hearing health promotion may benefit from tailoring intervention activities to best suit the stage of change of individuals. Different information may be useful at each stage to best support and motivate young people to look after their hearing health.
Ball, Jude; Hoek, Janet; Tautolo, El Shadan; Gifford, Heather
2017-12-10
Reducing smoking in young adults, particularly young Māori and Pacific, is vital for reducing tobacco harm and health inequalities in New Zealand (NZ). We investigated how NZ policy experts appraised the feasibility and likely effectiveness of interventions designed to reduce smoking prevalence among 18-24 year olds. We used a qualitative design, conducting semistructured interviews and applying thematic analysis. We interviewed 15 key informants, including politicians, senior policy analysts and leading tobacco control advocates. Participant selection was based on seniority and expertise and ensuring diverse perspectives were represented. We examined nine interventions that could either promote greater mindfulness or introduce barriers impeding smoking uptake: smoke-free outdoor dining and bars; no tobacco sales where alcohol is sold; social marketing campaigns; real life stories (testimonials); life skills training; raise purchase age to 21; tobacco-free generation; smokers' licence; make tobacco retail premises R18. The policies perceived as more effective denormalised tobacco; made it less convenient to access and use; highlighted immediate disadvantages (eg, impact on fitness); aligned with young people's values; and addressed the underlying causes of smoking (eg, stress). Participants highlighted some political barriers and noted concerns that some interventions might widen ethnic disparities. Exceptions were social marketing campaigns and extending smoke-free regulations to include outdoor areas of cafes and bars, which participants saw as politically feasible and likely to be effective. Our findings suggest the merit of an approach that combines social marketing with regulation that makes accessing and using tobacco less convenient for young adults; however, political barriers may limit the regulatory options available in the short term. Strategies to support self-determination and address the underlying causes of smoking in young people warrant further
An interlaboratory transfer of a multi-analyte assay between continents.
Georgiou, Alexandra; Dong, Kelly; Hughes, Stephen; Barfield, Matthew
2015-01-01
Alex has worked at GlaxoSmithKline for the past 15 years and currently works within the bioanalytical and toxicokinetic group in the United Kingdom. Alex's role in previous years has been the in-house support of preclinical and clinical bioanalysis, from method development through to sample analysis activities as well as acting as PI for GLP bioanalysis and toxicokinetics. For the past two years, Alex has applied this analytical and regulatory experience to focus on the outsourcing of preclinical bioanalysis, toxicokinetics and clinical bioanalysis, working closely with multiple bioanalytical and in-life CRO partners worldwide. Alex works to support DMPK and Safety Assessment outsourcing activities for GSK across multiple therapeutic areas, from the first GLP study through to late stage clinical PK studies. Transfer and cross-validation of an existing analytical assay between a laboratory providing current analytical support, and a laboratory needed for new or additional support, can present the bioanalyst with numerous challenges. These challenges can be technical or logistical in nature and may prove to be significant when transferring an assay between laboratories in different continents. Part of GlaxoSmithKline's strategy to improve confidence in providing quality data, is to cross-validate between laboratories. If the cross-validation fails predefined acceptance criteria, then a subsequent investigation would follow. This may also prove to be challenging. The importance of thorough planning and good communication throughout assay transfer, cross-validation and any subsequent investigations is illustrated in this case study.
Fox, Mary Murphy
2012-01-01
The current study investigated Theory of Mind in young adults with autism. The young adults with autism spectrum disorder (ASD) consisted of four students between the ages of 18 and 19 from an on-campus program for students with autism located at Marywood University in Northeastern Pennsylvania. It was hypothesized that "Mind Reading",…
Garner, Colin R; Park, Kevin B; French, Neil S; Earnshaw, Caroline; Schipani, Alessandro; Selby, Andrew M; Byrne, Lindsay; Siner, Sarah; Crawley, Francis P; Vaes, Wouter H J; van Duijn, Esther; deLigt, Rianne; Varendi, Heili; Lass, Jane; Grynkiewicz, Grzegorz; Maruszak, Wioletta; Turner, Mark A
2015-01-01
Aims The aims of the study were to compare [14C]-paracetamol ([14C]-PARA) paediatric pharmacokinetics (PK) after administration mixed in a therapeutic dose or an isolated microdose and to develop further and validate accelerator mass spectrometry (AMS) bioanalysis in the 0–2 year old age group. Methods [14C]-PARA concentrations in 10–15 µl plasma samples were measured after enteral or i.v. administration of a single [14C]-PARA microdose or mixed in with therapeutic dose in infants receiving PARA as part of their therapeutic regimen. Results Thirty-four infants were included in the PARA PK analysis for this study: oral microdose (n = 4), i.v. microdose (n = 6), oral therapeutic (n = 6) and i.v. therapeutic (n = 18). The respective mean clearance (CL) values (SDs in parentheses) for these dosed groups were 1.46 (1.00) l h–1, 1.76 (1.07) l h–1, 2.93 (2.08) l h–1 and 2.72 (3.10) l h–1, t1/2 values 2.65 h, 2.55 h, 8.36 h and 7.16 h and dose normalized AUC(0-t) (mg l–1 h) values were 0.90 (0.43), 0.84 (0.57), 0.7 (0.79) and 0.54 (0.26). Conclusions All necessary ethical, scientific, clinical and regulatory procedures were put in place to conduct PK studies using enteral and systemic microdosing in two European centres. The pharmacokinetics of a therapeutic dose (mg kg–1) and a microdose (ng kg–1) in babies between 35 to 127 weeks post-menstrual age. [14C]-PARA pharmacokinetic parameters were within a two-fold range after a therapeutic dose or a microdose. Exploratory studies using doses significantly less than therapeutic doses may offer ethical and safety advantages with increased bionalytical sensitivity in selected exploratory paediatric pharmacokinetic studies. PMID:25619398
Garner, Colin R; Park, Kevin B; French, Neil S; Earnshaw, Caroline; Schipani, Alessandro; Selby, Andrew M; Byrne, Lindsay; Siner, Sarah; Crawley, Francis P; Vaes, Wouter H J; van Duijn, Esther; deLigt, Rianne; Varendi, Heili; Lass, Jane; Grynkiewicz, Grzegorz; Maruszak, Wioletta; Turner, Mark A
2015-07-01
The aims of the study were to compare [(14)C]-paracetamol ([(14)C]-PARA) paediatric pharmacokinetics (PK) after administration mixed in a therapeutic dose or an isolated microdose and to develop further and validate accelerator mass spectrometry (AMS) bioanalysis in the 0-2 year old age group. [(14)C]-PARA concentrations in 10-15 µl plasma samples were measured after enteral or i.v. administration of a single [(14)C]-PARA microdose or mixed in with therapeutic dose in infants receiving PARA as part of their therapeutic regimen. Thirty-four infants were included in the PARA PK analysis for this study: oral microdose (n = 4), i.v. microdose (n = 6), oral therapeutic (n = 6) and i.v. therapeutic (n = 18). The respective mean clearance (CL) values (SDs in parentheses) for these dosed groups were 1.46 (1.00) l h(-1), 1.76 (1.07) l h(-1), 2.93 (2.08) l h(-1) and 2.72 (3.10) l h(-1), t(1/2) values 2.65 h, 2.55 h, 8.36 h and 7.16 h and dose normalized AUC(0-t) (mg l(-1) h) values were 0.90 (0.43), 0.84 (0.57), 0.7 (0.79) and 0.54 (0.26). All necessary ethical, scientific, clinical and regulatory procedures were put in place to conduct PK studies using enteral and systemic microdosing in two European centres. The pharmacokinetics of a therapeutic dose (mg kg(-1)) and a microdose (ng kg(-1)) in babies between 35 to 127 weeks post-menstrual age. [(14)C]-PARA pharmacokinetic parameters were within a two-fold range after a therapeutic dose or a microdose. Exploratory studies using doses significantly less than therapeutic doses may offer ethical and safety advantages with increased bionalytical sensitivity in selected exploratory paediatric pharmacokinetic studies. © 2015 The British Pharmacological Society.
Wong, Agnes; Peiris-John, Roshini; Sobrun-Maharaj, Amritha; Ameratunga, Shanthi
2015-12-01
The proportion of young people in New Zealand identifying with Asian ethnicities has increased considerably. Despite some prevalent health concerns, Asian youth are less likely than non-Asian peers to seek help. As preparatory research towards a more nuanced approach to service delivery and public policy, this qualitative study aimed to identify young Asian New Zealanders' perspectives on best approaches to investigate health issues of priority concern to them. Three semi-structured focus group discussions were conducted with 15 Asian youth leaders aged 18-24 years. Using an inductive approach for thematic analysis, key themes were identified and analysed. Study participants considered ethno-cultural identity, racism and challenges in integration to play significant roles influencing the health of Asian youth (especially mental health) and their access to health services. While emphasising the importance of engaging young Asians in research and service development so that their needs and aspirations are met, participants also highlighted the need for approaches that are cognisant of the cultural, contextual and intergenerational dimensions of issues involved in promoting youth participation. Research that engages Asian youth as key agents using methods that are sensitive to their cultural and sociological contexts can inform more responsive health services and public policy. This is of particular relevance in primary health care where culturally competent services can mitigate risks of unmet health needs and social isolation.
Flores, Glenn; Mendoza, Fernando S; Fuentes-Afflick, Elena; Mendoza, Jason A; Pachter, Lee; Espinoza, Juan; Fernandez, Cristina R; Arnold, Danielle D P; Brown, Nicole M; Gonzalez, Kymberly M; Lopez, Cynthia; Owen, Mikah C; Parks, Kenya M; Reynolds, Kimberly L; Russell, Christopher J
2016-12-09
The number of racial/ethnic minority children will exceed the number of white children in the USA by 2018. Although 38% of Americans are minorities, only 12% of pediatricians, 5% of medical-school faculty, and 3% of medical-school professors are minorities. Furthermore, only 5% of all R01 applications for National Institutes of Health grants are from African-American, Latino, and American Indian investigators. Prompted by the persistent lack of diversity in the pediatric and biomedical research workforces, the Academic Pediatric Association Research in Academic Pediatrics Initiative on Diversity (RAPID) was initiated in 2012. RAPID targets applicants who are members of an underrepresented minority group (URM), disabled, or from a socially, culturally, economically, or educationally disadvantaged background. The program, which consists of both a research project and career and leadership development activities, includes an annual career-development and leadership conference which is open to any resident, fellow, or junior faculty member from an URM, disabled, or disadvantaged background who is interested in a career in academic general pediatrics. As part of the annual RAPID conference, a Hot Topic Session is held in which the young investigators spend several hours developing a list of hot topics on the most useful faculty and career-development issues. These hot topics are then posed in the form of six "burning questions" to the RAPID National Advisory Committee (comprised of accomplished, nationally recognized senior investigators who are seasoned mentors), the RAPID Director and Co-Director, and the keynote speaker. The six compelling questions posed by the 10 young investigators-along with the responses of the senior conference leadership-provide a unique resource and "survival guide" for ensuring the academic success and optimal career development of young investigators in academic pediatrics from diverse backgrounds. A rich conversation ensued on the topics
Adamczyk, Katarzyna
2017-01-01
The present study tested the hypothesis that single young adults who perceive their singlehood as voluntary would report a higher level of positive mental health (i.e., emotional, psychological and social well-being), lower levels of mental health illness (i.e., somatic symptoms, anxiety, social dysfunction, severe depression) and romantic loneliness in comparison to young adults who perceive their singlehood as involuntary. This paper also investigated whether romantic loneliness mediates the relationship between voluntary and involuntary singlehood, positive mental health, and mental health illness. The study sample included 151 participants (86 females and 65 males) aged 20-26 ( M = 22.48, SD = 2.01) from Poland. The main findings were that voluntarily single young adults reported a lower level of romantic loneliness compared to involuntarily single young adults. The two groups differed neither in regard to positive mental health nor in regard to mental health problems. In addition, gender differences were observed solely in the domain of romantic loneliness, with women reporting greater romantic loneliness than men. The mediation analysis revealed that romantic loneliness does not mediate the relationship between voluntary and involuntary singlehood, positive mental health, and mental health illness. Voluntary and involuntary singlehood was predictive of somatic symptoms, anxiety and insomnia, severe depression, and romantic loneliness.
Conforto, Adriana Bastos; Fregni, Felipe; Puglia, Paulo; Leite, Claudia da Costa; Yamamoto, Fabio Iuji; Coracini, Karen F; Scaff, Milberto
2006-06-01
We preliminarily investigated the relevance of performing digital subtraction angiography (DSA) in addition to magnetic resonance angiography (MRA) in definition of ischemic stroke etiology in young patients. DSAs and MRAs from 17 young patients with nonlacunar ischemic stroke were blindly analyzed and their impact on stroke management was evaluated. Etiologies were the same considering results of either DSA or MRA in 12/17 cases. In 15/17 patients no changes would have been made in treatment, regardless of the modality of angiography considered. These preliminary results suggest that DSA may be redundant in two thirds of ischemic strokes in young patients. Further larger prospective studies are necessary to determine indications of DSA in this age group.
Jiang, Hao; Ouyang, Zheng; Zeng, Jianing; Yuan, Long; Zheng, Naiyu; Jemal, Mohammed; Arnold, Mark E
2012-06-01
Biological sample dilution is a rate-limiting step in bioanalytical sample preparation when the concentrations of samples are beyond standard curve ranges, especially when multiple dilution factors are needed in an analytical run. We have developed and validated a Microsoft Excel-based robotic sample preparation program (RSPP) that automatically transforms Watson worklist sample information (identification, sequence and dilution factor) to comma-separated value (CSV) files. The Freedom EVO liquid handler software imports and transforms the CSV files to executable worklists (.gwl files), allowing the robot to perform sample dilutions at variable dilution factors. The dynamic dilution range is 1- to 1000-fold and divided into three dilution steps: 1- to 10-, 11- to 100-, and 101- to 1000-fold. The whole process, including pipetting samples, diluting samples, and adding internal standard(s), is accomplished within 1 h for two racks of samples (96 samples/rack). This platform also supports online sample extraction (liquid-liquid extraction, solid-phase extraction, protein precipitation, etc.) using 96 multichannel arms. This fully automated and validated sample dilution and preparation process has been applied to several drug development programs. The results demonstrate that application of the RSPP for fully automated sample processing is efficient and rugged. The RSPP not only saved more than 50% of the time in sample pipetting and dilution but also reduced human errors. The generated bioanalytical data are accurate and precise; therefore, this application can be used in regulated bioanalysis.
Tan, Aimin; Saffaj, Taoufiq; Musuku, Adrien; Awaiye, Kayode; Ihssane, Bouchaib; Jhilal, Fayçal; Sosse, Saad Alaoui; Trabelsi, Fethi
2015-03-01
The current approach in regulated LC-MS bioanalysis, which evaluates the precision and trueness of an assay separately, has long been criticized for inadequate balancing of lab-customer risks. Accordingly, different total error approaches have been proposed. The aims of this research were to evaluate the aforementioned risks in reality and the difference among four common total error approaches (β-expectation, β-content, uncertainty, and risk profile) through retrospective analysis of regulated LC-MS projects. Twenty-eight projects (14 validations and 14 productions) were randomly selected from two GLP bioanalytical laboratories, which represent a wide variety of assays. The results show that the risk of accepting unacceptable batches did exist with the current approach (9% and 4% of the evaluated QC levels failed for validation and production, respectively). The fact that the risk was not wide-spread was only because the precision and bias of modern LC-MS assays are usually much better than the minimum regulatory requirements. Despite minor differences in magnitude, very similar accuracy profiles and/or conclusions were obtained from the four different total error approaches. High correlation was even observed in the width of bias intervals. For example, the mean width of SFSTP's β-expectation is 1.10-fold (CV=7.6%) of that of Saffaj-Ihssane's uncertainty approach, while the latter is 1.13-fold (CV=6.0%) of that of Hoffman-Kringle's β-content approach. To conclude, the risk of accepting unacceptable batches was real with the current approach, suggesting that total error approaches should be used instead. Moreover, any of the four total error approaches may be used because of their overall similarity. Lastly, the difficulties/obstacles associated with the application of total error approaches in routine analysis and their desirable future improvements are discussed. Copyright © 2015 Elsevier B.V. All rights reserved.
DEFF Research Database (Denmark)
Westlund, Oscar; Bjur, Jakob
2014-01-01
This is a thorough investigation into contemporary young people and their media life. The article conceptualizes a typology of media life, drawing on a theoretical body involving the sociology of generations, life course research, media life and individualization. This empirically derived typology...... makes a strong instrument for an understanding of the media life of the young, furnishing insights into how they have constructed their use of media. The investigation is based on a robust national survey with Swedes born 1994–2001, conducted in 2010, and focusing on four media: television, gaming......, the Internet and mobile devices. Two of the findings are particularly surprising. Firstly, the results reveal that the young generally lead heterogeneous media lives, varying with age and sex. Secondly, although some young people literarily live their life in media, there are also de facto young who live...
Directory of Open Access Journals (Sweden)
İbrahim GİRİTLİOĞLU
2013-12-01
Full Text Available The aim of this study is to identify of local young tourists’ purpose of visit at night clubswhen they go on holiday and to investigate their consumption behavior when they use nightclub services. To perform on this aim, the developed questionnaire form is filled out by 276Turkish tourists who attended local tourism activities between the months of March andAugust 2013 and attended night club activities at least once when they were on holiday.According to the findings of the study, male tourists visited night clubs more frequentlythan females when they were on holiday while a high proportion of the young touristsstayed at night clubs for almost three hours.
An investigation of young girls' responses to sexualized images.
Jongenelis, Michelle I; Pettigrew, Simone; Byrne, Susan M; Biagioni, Nicole
2016-12-01
Evidence suggests that the sexualization of girls has increased and become more explicit in recent years. However, most of the research conducted to date has focused on sexualization in adults. To address this research gap, this study explored how young Australian girls respond to and describe sexualized and non-sexualized depictions of their peers. Results from 42 girls aged 6-11 years revealed that sexualization was a perceptually salient attribute, with participants readily classifying sexualized girls as a subgroup. Participants also made distinct trait attributions based on the differences between sexualized and non-sexualized girls. The results suggest that young girls respond differently to sexualized and non-sexualized depictions of their peers and are beginning to develop stereotypes based on these depictions. As such, the implementation of media literacy programs in adolescence may be too late and efforts may be required to address this issue among younger children. Copyright © 2016 Elsevier Ltd. All rights reserved.
Directory of Open Access Journals (Sweden)
Zeno Nols
2017-06-01
Full Text Available Critical scholars have indicated that the assumptions underlying most sport-for-development (SFD initiatives tend to align with a ‘deficit model’ of youth: young people from disadvantaged areas are uniformly deficient and in need of development, which can be achieved through sport (Coakley, 2011; Coalter, 2013. In this article, we investigated these assumptions within six urban SFD initiatives that work with young people in socially vulnerable situations in a ‘first’ world nation, Belgium. We conducted a survey at two moments in time amongst 14- to 25-year-old participants in order to test two assumptions: i ‘participants are deficient and in need of development’; and ii ‘participation in SFD initiatives leads to positive personal development’. We operationalised ‘development’ as the commonly used outcomes of perceived self-efficacy and self-esteem. These are ‘household words’ both inside and outside SFD research, practice, and policy and carry the assumption that boosting them will by itself foster positive outcomes. The findings refute the supposition that young people from disadvantaged urban areas are uniformly in need of more perceived self-efficacy and self-esteem and show that there is no simple and predictable change in participants’ ‘development’. We suggest that, in designing and researching programs, SFD stakeholders start from an open-ended bottom-up approach which is tailored to the actual life situations of young people and their individual differences and consider more interpersonal and critical conceptualisations of ‘development’.
KRIM, Sihem
2015-01-01
This present work tries to investigate how language is used electronically among the young Algerian users of Internet, and if they use English or not. For doing this study, a case study was conducted at Tlemcen University: English Department relying on two main research instruments: students’ questionnaire and teachers’ interview. After collecting data from the respondents( 20 Master 1 students and 8 teachers), the results reveal that the majority of participants use English vi...
Motions in Digital Young Adult Literature
DEFF Research Database (Denmark)
Henkel, Ayoe Qvist
Abstract (in English): The digital turn brings about not only changes in young adult literature considered as aesthetic artifacts and literary works but also changes in the perception and reception of the reader. Digital young adult literature is increasingly multimodal and interactive...... will be the focal point here. The pivotal point of this paper will be exploring how transgressing analytical categories, e.g. rhythm, sequentiality, time, space and dialogue with the reader, can shed light on the formation of meaning in a specific digital young adult literary work, i.e. Tavs (Camilla Hübbe, Rasmus......, the paper will investigate the ‘denaturalization’ of the reading process and it will attempt to investigate and offer analytical categories which can be used also by young readers so that they can become competent cross media readers of young adult literature in a digitalized and medialized landscape...
Buchanan, Limin; Kelly, Bridget; Yeatman, Heather
2017-01-01
Young adults experience faster weight gain and consume more unhealthy food than any other age groups. The impact of online food marketing on "digital native" young adults is unclear. This study examined the effects of online marketing on young adults' consumption behaviours, using energy drinks as a case example. The elaboration likelihood model of persuasion was used as the theoretical basis. A pre-test post-test experimental research design was adopted using mixed-methods. Participants (age...
2017-09-30
Report: Young Investigator Proposal, Research Area 7.4 Reactive Chemical Systems: Multifunctional, Bimetallic Nanomaterials Prepared by Atomic Layer ...Chemical Systems: Multifunctional, Bimetallic Nanomaterials Prepared by Atomic Layer Electroless Deposition Report Term: 0-Other Email: pcappillino... Layer Electroless Deposition (ALED, Figure 1) is the ability to tune growth mechanism, hence growth morphology, by altering conditions. In this
Buchanan, Limin; Kelly, Bridget; Yeatman, Heather
2017-01-01
Young adults experience faster weight gain and consume more unhealthy food than any other age groups. The impact of online food marketing on "digital native" young adults is unclear. This study examined the effects of online marketing on young adults' consumption behaviours, using energy drinks as a case example. The elaboration likelihood model of persuasion was used as the theoretical basis. A pre-test post-test experimental research design was adopted using mixed-methods. Participants (aged 18-24) were randomly assigned to control or experimental groups (N = 30 each). Experimental group participants' attitudes towards and intended purchase and consumption of energy drinks were examined via surveys and semi-structured interviews after their exposure to two popular energy drink brands' websites and social media sites (exposure time 8 minutes). Exposure to digital marketing contents of energy drinks improved the experimental group participants' attitudes towards and purchase and consumption intention of energy drinks. This study indicates the influential power of unhealthy online marketing on cognitively mature young adults. This study draws public health attentions to young adults, who to date have been less of a focus of researchers but are influenced by online food advertising.
Buchanan, Limin; Kelly, Bridget; Yeatman, Heather
2017-01-01
Young adults experience faster weight gain and consume more unhealthy food than any other age groups. The impact of online food marketing on “digital native” young adults is unclear. This study examined the effects of online marketing on young adults’ consumption behaviours, using energy drinks as a case example. The elaboration likelihood model of persuasion was used as the theoretical basis. A pre-test post-test experimental research design was adopted using mixed-methods. Participants (aged 18–24) were randomly assigned to control or experimental groups (N = 30 each). Experimental group participants’ attitudes towards and intended purchase and consumption of energy drinks were examined via surveys and semi-structured interviews after their exposure to two popular energy drink brands’ websites and social media sites (exposure time 8 minutes). Exposure to digital marketing contents of energy drinks improved the experimental group participants’ attitudes towards and purchase and consumption intention of energy drinks. This study indicates the influential power of unhealthy online marketing on cognitively mature young adults. This study draws public health attentions to young adults, who to date have been less of a focus of researchers but are influenced by online food advertising. PMID:28152016
Grant, Sean; Pedersen, Eric R; Neighbors, Clayton
2016-05-01
This study involves a pilot investigation of associations between marijuana and synthetic cannabis use with PTSD symptoms among a young adult sample of U.S. veterans. In a cross-sectional survey of a community sample of 790 young adult U.S. veterans, we assessed demographics, combat severity, marijuana and synthetic cannabis use, expectancies of marijuana use, and PTSD symptoms. Overall, 61.8% and 20.4% of our sample reported lifetime and past-month marijuana use, whereas 17.0% and 3.4% reported lifetime and past-month synthetic cannabis use. Veterans screening positive for PTSD were more likely to use marijuana and synthetic cannabis in their lifetime and in the past month. Positive PTSD screens, as well as greater expectancies that marijuana leads to relaxation and tension reduction, were associated with past-month marijuana use in logistic regression analyses. Expectancies moderated the relationship between PTSD and marijuana use, such that those with positive PTSD screens reporting higher levels of relaxation and tension-reduction expectancies were most likely to report past-month marijuana use. Our findings suggest an association of PTSD symptoms with marijuana and synthetic cannabis use among young adult U.S. veterans. Future research should further investigate the link between PTSD and marijuana use, as well as the rates and consequences of synthetic cannabis use among veterans.
Well Begun is Half Done: Investigating the Work and Career of the Young Workforce
Akkermans, T.J.
2013-01-01
Young workers are faced with many unique challenges when they start their professional careers, and especially young workers with lower levels of education may need support in managing their work and career as their work is becoming ever more complex and they have been struck hardest by the recent
Investigating Young Children's Perceptions of Body Size and Healthy Habits
Xu, Tingting; Nerren, Jannah S.
2017-01-01
Attitudes and biases toward body size perceived as fat and body size perceived as thin are present in young children (Cramer and Steinwert in "J Appl Dev Psychol" 19(3):429-451, 1998; Worobey and Worobey in "Body Image" 11:171-174, 2014). However, the information children have regarding body size and ways to modify body size…
An overview of the China Bioanalytical Forum: interview with Daniel Tang.
Tang, Daniel
2017-02-01
Daniel Tang talks to Sankeetha Nadarajah, Commissioning Editor (Bioanalysis), regarding the China Bioanalysis Forum (CBF), in which Daniel was one of the co-founders and remains as its co-chair. Daniel is currently the CEO of UP Pharma, a biologics focused bioanalytical CRO in China.
2011-07-01
This paper describes a framework for a multi-disciplinary collaboration to investigate the role of technology for improving young Australians' mental health and wellbeing. The poor mental health of young Australians poses a significant challenge to Australia's future. Half of all Australians will experience a mental health difficulty in their lifetime and 75% of mental illness has its onset before age 25. Cross-sectoral collaboration is critical for meeting this challenge. In order to establish a world-first multi-partner collaboration, leading researchers and institutes, commercial, non-profit and end-user organization and young people were identified and invited to participate. Together we have developed an international research framework that explores the role of technologies in young people's lives, their potential and how this can be harnessed to address challenges facing young people. This research framework will: (i) conduct empirical research that tests the utility of technology across mental health promotion, prevention, early intervention and treatment and, (ii) translate existing and new knowledge into products and services that help create a generation of safe, happy, healthy and resilient young people. Research undertaken by the Collaboration will be the most comprehensive investigation of technologies' potential to improve the wellbeing of young people ever conducted, leading to significant benefits for Australian young people and their mental health.
Linscheid, Michael W
2018-03-30
slightly adapted workflows, already in use for quantification in bioanalysis. Imaging mass spectrometry (MSI) with MALDI and laser ablation ICP-MS complemented the range of application in recent years. © 2018 Wiley Periodicals, Inc.
Socially Vulnerable Young People in Flemish Sports Clubs: Investigating Youth Experiences
Haudenhuyse, Reinhard; Theeboom, Marc; Nols, Zeno; Coussée, Filip
2014-01-01
Sport appears to present a powerful tool for engaging socially vulnerable youth in an organised context, which offers an opportunity to work with them. However, we have little understanding regarding participation of socially vulnerable young people in the "traditional" sport sector (i.e. sports clubs). Nor do we have sufficient insights…
On imitation among young and blind children
Directory of Open Access Journals (Sweden)
Maria Rita Campello Rodrigues
2016-07-01
Full Text Available This article investigates the imitation among young and blind children. The survey was conducted as a mosaic in the time since the field considerations were taken from two areas: a professional experience with early stimulation of blind babies and a workshop with blind and low vision young between 13-18 years. By statingthe situated trace of knowledge, theresearch indicates that imitation among blind young people can be one of the ways of creating a common world among young blind and sighted people. Imitation among blind young is a multi-sensory process that requires a body experience, including both blind and people who see. The paper concludes with an indication of the unique character of imitation and at the same time, with the affirmation of its relevance to the development and inclusion process of both the child and the young blind.
Ihle, Andreas; Jopp, Daniela S; Oris, Michel; Fagot, Delphine; Kliegel, Matthias
2016-11-05
Health research suggests that findings on young-old adults cannot be generalized to old-old adults and thus that old-old age seems not a simple continuation of young-old age due to qualitative changes that result in a discontinuity in old age. Specifically, it would be of conceptual and methodological importance to inform research regarding estimates around which chronological age the beginning of old-old age could be placed at a population level, and whether this is universal or domain-specific. To derive such criteria, we investigated potential discontinuity of age relations between young-old and old-old age in a large population-based sample considering measures in different domains (processing speed, verbal abilities, general health status, activity participation, and life satisfaction). For processing speed, verbal abilities, general health status, and life satisfaction we observed some very small indication that there might be a discontinuity of age relations at the end of individuals' eighties, and for activity participation already at the beginning of individuals' eighties. In conclusion, models conceptualizing aging as a gradual development might not suffice to adequately represent the differences between the stages of young-old and old-old age due to some very small indication that there might be discontinuity in late adulthood.
Schepis, Ty S; Tapscott, Brian E; Krishnan-Sarin, Suchitra
2016-04-01
Substantial evidence links greater impulsivity and stress exposure to poorer smoking cessation outcomes. Results from adolescents also indicate that stress-related change in risk taking can impede cessation attempts. We investigated the effects of stress-related change in impulsivity, risk taking, attention and nicotine withdrawal, and craving in young adult smokers on time to smoking relapse in a relapse analogue paradigm. Twenty-six young adult smokers (50% women; mean age: 20.9 ± 1.8) were exposed to a stress imagery session followed by a contingency management-based relapse analogue paradigm. Participants smoked at least 5 cigarettes daily, with a mean baseline carbon monoxide (CO) level of 13.7 (± 5.1) ppm. Repeated measures analysis of variance (ANOVA) and paired t tests examined stress induction validity and Cox regressions of proportional hazards examined the effects of stress-related changes in nicotine withdrawal, nicotine craving, attention, impulsivity, and risk taking on time to relapse. While stress-related change in impulsivity, nicotine craving and withdrawal did not predict time to relapse (all ps > .10), greater stress-related increases in reaction time (RT) variability (p = .02) were predictive of shorter time to relapse, with trend-level findings for inattention and risk taking. Furthermore, changes in stress-related risk taking affected outcome in women more than in men, with a significant relationship between stress-related change in risk taking only in women (p = .026). Smoking cessation attempts in young adults may be adversely impacted by stress-related increases in risk taking and attentional disruption. Clinicians working with young adults attempting cessation may need to target these stress-related impairments by fostering more adaptive coping and resilience. (c) 2016 APA, all rights reserved).
Attitudes of Kuwaiti Young Adults toward Marriage and Divorce:
Humoud Alqashan; Hayfaa Alkandari
2010-01-01
This study investigates whether parental marital status affects young adults’ attitudes toward marriage and divorce. There exists a vast amount of literature on the impact of divorce on young adults in Western cultures; however, no previous empirical studies have been conducted on the attitudes of young adults from intact and divorced families in the Gulf region or in Arab countries in the Middle East. The sample of the study consisted of 661 young adults from Kuwait University (from divorced...
Determinants of vitamin D status in young adults
DEFF Research Database (Denmark)
Tønnesen, Rune; Hovind, Peter Hambak; Jensen, Lars Thorbjørn
2016-01-01
BACKGROUND: Very few studies have investigated the determinants of circulating 25-hydroxyvitamin D (25[OH]D) in young adults (18-25 years old) using a set of variables that include lifestyle, sociodemographic, and anthropometric data. Our aim was to investigate the association between...... these variables and vitamin D status in a sample of untreated young adults. METHODS: A total of 738 young adults were enrolled in a (June cross-sectional study 2012 to May 2014) and were recruited from educational institutions in the Copenhagen area. For multivariate logistic regression subjects was categorized.......68). For vitamin D insufficiency, the highest RR was again for men 1.31 (1.06, 1.61); obese subjects 1.57 (1.17, 2.11); and subjects who exercised 0-½ hours a week 1.51 (1.11, 2.06). CONCLUSION: In this study of young adults, vitamin D deficiency was highly prevalent. Modifiable factors such as smoking...
Directory of Open Access Journals (Sweden)
Yanwei Li
2018-02-01
Full Text Available Autism is a neurodevelopmental disorder with dimensional behavioral symptoms and various damages in the structural and functional brain. Previous neuroimaging studies focused on exploring the differences of brain development between individuals with and without autism spectrum disorders (ASD. However, few of them have attempted to investigate the individual differences of the brain features among subjects within the Autism spectrum. Our main goal was to explore the individual differences of neurodevelopment in young children with Autism by testing for the association between the functional network efficiency and levels of autistic behaviors, as well as the association between the functional network efficiency and age. Forty-six children with Autism (ages 2.0–8.9 years old participated in the current study, with levels of autistic behaviors evaluated by their parents. The network efficiency (global and local network efficiency were obtained from the functional networks based on the oxy-, deoxy-, and total-Hemoglobin series, respectively. Results indicated that the network efficiency decreased with age in young children with Autism in the deoxy- and total-Hemoglobin-based-networks, and children with a relatively higher level of autistic behaviors showed decreased network efficiency in the oxy-hemoglobin-based network. Results suggest individual differences of brain development in young children within the Autism spectrum, providing new insights into the psychopathology of ASD.
Development of Young Coconut (Cocos nucifera Wine
Directory of Open Access Journals (Sweden)
Polemer M. Cuarto
2017-05-01
Full Text Available The study aimed to develop wine from young coconut water. This investigated the acceptability of the quality attributes of young coconut wine compared with commercial wine. Using a 5 - point hedonic scale, sensory evaluation test was done by the panelists (N=30 to evaluate the accep tability of the product quality attributes such as color, aroma and taste. Results of the sensory evaluation showed that young coconut wine has a pale light color, powerful aroma and sweet taste. Results also showed that panelists choose the color and tast e of the young coconut wine as its desirable attributes. Statistical analysis (p<0.05 showed significant difference in the color and aroma between young coconut wine and commercial wine but no significant difference in terms of taste.
Derlan, Chelsea L; Umaña-Taylor, Adriana J; Toomey, Russell B; Jahromi, Laudan B; Updegraff, Kimberly A
2016-07-01
We describe the development and psychometric testing of the Cultural Socialization Behaviors Measure (CSBM) and the Cultural Socialization Attitudes Measure (CSAM). The CSBM assesses cultural socialization behaviors that parents use with young children, and the CSAM assesses the attitudes that parents have regarding the importance of socializing their young children about their culture. Both measures demonstrated strong reliability, validity, and cross-language equivalence (i.e., Spanish and English) among a sample of 204 Mexican-origin young mothers ( M age = 20.94 years, SD = 1.01) with 4-year-old children. In addition, the measures demonstrated longitudinal equivalence when children were 4 and 5 years of age.
Group Theory, Computational Thinking, and Young Mathematicians
Gadanidis, George; Clements, Erin; Yiu, Chris
2018-01-01
In this article, we investigate the artistic puzzle of designing mathematics experiences (MEs) to engage young children with ideas of group theory, using a combination of hands-on and computational thinking (CT) tools. We elaborate on: (1) group theory and why we chose it as a context for young mathematicians' experiences with symmetry and…
Molecular basis of young ischemic stroke.
Bersano, Anna; Borellini, Linda; Motto, Cristina; Lanfranconi, Silvia; Pezzini, Alessandro; Basilico, Paola; Micieli, Giuseppe; Padovani, Alessandro; Parati, Eugenio; Candelise, Livia
2013-01-01
Epidemiological and family studies have provided evidence on the role of genetic factors in stroke, particularly in stroke occurring at young age. However, despite its impact, young stroke continues to be understudied. This article reviews the existing literature on the most investigated monogenic disorders (CADASIL, Fabry disease, MELAS, RVCL, COL4A1, Marfan and Ehlers-Danlos syndromes) causing stroke in young and a number of candidate genes associated with stroke occurring in patients younger than 50 years. Although our study failed in identifying strong and reliable associations between specific genes and young stroke, our detailed literature revision on the field allowed us to compile a panel of genes possibly generating a susceptibility to stroke, which could be a starting point for future research. Since stroke is a potentially preventable disease, the identification of genes associated with young stroke may promote novel prevention strategies and allow the identification of therapeutic disease targets.
Psychological characteristics of aggressors of young couple
Directory of Open Access Journals (Sweden)
María Jesús Hernández Jiménez
2014-10-01
Full Text Available Violence against women in relationships young people has become in recent years a public health problem of major social. This article, with a view to the prevention, seeks to address the psychological characteristics of the perpetrator of pair in young relations. An initial review of the personality features investigated in previous studies and their influence on violent behaviour was carried out. Following this, an empirical study on a sample of young people was performed. Methods: We conducted a study with 100 young people of Valencia. Of these, 50 are young offenders and 50 couple, young students of compulsory secondary education. Data are obtained and analyzed psychological characteristics differences between groups. Results: The study conducted shows that in general, young offenders have one hand high scores on neuroticism, impulsivity, external locus of control, psychoticism and antisocial behavior. Furthermore show low scores on self-control, empathy, selfesteem and frustration tolerance. Conclusions: The results of this paper make it abundantly clear that violence in young relationships is important enough to be considered from different sectors of society and justifies the need to develop and implement prevention programs adapted adolescents and their characteristics.
Directory of Open Access Journals (Sweden)
Rico S C Lee
Full Text Available BACKGROUND: Clinical symptoms and neuropsychological deficits are longitudinally associated with functional outcome in chronic psychiatric cohorts. The current study extended these findings to young and early-course psychiatric outpatients, with the aim of identifying cognitive markers that predict later socio-occupational functioning. METHODS: At baseline, 183 young psychiatric outpatients were assessed. Ninety-three returned for follow-up (M = 21.6 years old; SD = 4.5 with an average re-assessment interval of 21.6 months (SD = 7.0, and primary diagnoses of major depressive disorder (n = 34, bipolar disorder (n = 29, or psychosis (n = 30. The primary outcome measure was cross-validated with various other functional measures and structural equation modelling was used to map out the interrelationships between predictors and later functional outcome. RESULTS: Good socio-occupational functioning at follow-up was associated with better quality of life, less disability, current employment and being in a romantic relationship. The final structural equation model explained 47.5% of the variability in functional outcome at follow-up, with baseline neuropsychological functioning (a composite of memory, working memory and attentional switching the best independent predictor of later functional outcome. Notably, depressive and negative symptoms were only associated with functioning cross-sectionally. Diagnosis at follow-up was not associated with functional outcome. CONCLUSIONS: Neuropsychological functioning was the single best predictor of later socio-occupational outcome among young psychiatric outpatients. Therefore, framing psychiatric disorders along a neuropsychological continuum is likely to be more useful in predicting functional trajectory than traditional symptom-based classification systems. The current findings also have implications for early intervention utilising cognitive remediation approaches.
Risk Perception in Young Women's Collective Alcohol Consumption
Dresler, Emma; Anderson, Margaret
2017-01-01
Purpose: Heavy episodic drinking in young women has caused concern among many groups including public health professionals. The purpose of this paper is to investigate the experiences of young women's alcohol consumption so as to facilitate better health education targeting. Design/methodology/approach: This qualitative descriptive study examines…
Supportive Housing in Foster Care: The Views of Young People
Sinkkonen, Hanna-Maija; Kyttälä, Minna
2015-01-01
This study investigated Finnish young people's experiences of supportive housing. Supportive housing is an after-care programme that should support the transition from foster care to independent adulthood. It is directed mainly at young people who have been taken into foster care by social workers. The sample consisted of 39 young people (23…
Sexting and investigation of materials with child sexual abuse
Directory of Open Access Journals (Sweden)
Polona Sladič
2016-09-01
Full Text Available Research Question (RQ: How widespread is the phenomenon of sexting among young people? Are young people sufficiently aware about this subject? Any difficulties encountered when investigating sexting? Purpose: The purpose of this paper is to present problems in investigating sexting. Since using Internet child pornography expanded and changed the way the investigation of this crime, it is necessary to explore new ways of investigating and overcoming problems in the investigation of more attention. Method: The article is transparent and theoretical. It is based primarily on an analysis of available domestic and foreign literature and Internet sources on the issues addressed. Results: Showing sexting consequences of abuse, and also provides some preventive tips for safest use the Internet. In conclusion, the investigators also presented problems in the investigation of crimes related to sex abuse with minors. Society: The survey alert to be aware of the problem among young people. We emphasize the importance of raising awareness of young people and the importance of the application of possible abuse. Originality: The originality of the contribution is reflected in the examination of the current investigation sexting problems, faced by investigators on a daily basis. Only in this way it can eliminate problems and improve search. Limitations/Future Research: Using sexting appear high risk, but they are young without consulting the parents are not aware of. It is necessary to invest more effort into raising awareness of young people and create an environment that will encourage victims to report abuse.
Young British readers' engagement with manga
Tsai, Yi-Shan
2015-01-01
This thesis presents young British readers’ engagement with manga regarding literary, aesthetic, social, and cultural dimensions. The study explores young readers’ points of views of their reading preference – manga. I investigated how children interpreted manga, with respect to the artistic techniques, the embedded ideologies, and the cultural elements therein. I also looked into children’s participation in manga fandom and its social meanings. This allowed me to explore what attracted Briti...
Raby, K. Lee; Cicchetti, Dante; Carlson, Elizabeth A.; Egeland, Byron; Collins, W. Andrew
2013-01-01
Background Longitudinal research has demonstrated that individual differences in attachment security show only modest continuity from infancy to adulthood. Recent findings based on retrospective reports suggest that individuals’ genetic variation may moderate the developmental associations between early attachment-relevant relationship experiences and adult attachment security. The purpose of this study was to use a prospective, longitudinal design to investigate genetic contributions to continuity and changes in attachment security from infancy to young adulthood in a higher risk sample. Methods Infant attachment security was assessed using the Strange Situation Procedure at 12 and 18 months. Adults’ general attachment representations were assessed using the Adult Attachment Interview at age 19 and age 26. Romantic attachment representations were assessed with the Current Relationship Interview at ages 20–21 and ages 26–28. Individuals were genotyped for variants within the oxytocin receptor (OXTR), dopamine D4 receptor (DRD4), and serotonin transporter linked polymorphic region (5-HTTLPR). Results The continuity of attachment security from infancy into young adulthood was consistently moderated by OXTR genetic variation. Infant attachment security predicted the security of adults’ general and romantic attachment representations only for individuals with the OXTR G/G genotype. This interaction was significant when predicting adult attachment security as measured by the Adult Attachment Interview at age 19 and 26 and the Current Relationship Interview at ages 26–28. DRD4 and 5-HTTLPR genetic variation did not consistently moderate the longitudinal associations between attachment security during infancy and adulthood. Conclusions This study provides initial longitudinal evidence for genetic contributions to continuity and change in attachment security from infancy to young adulthood. Genetic variation related to the oxytocin system may moderate the
Conference report: moving forward together: "we are making progress".
van Dongen, William D; Renfurm, Luuk C
2014-05-01
The 6th European Bioanalysis Forum Open Meeting 20-22 November 2013, Hesperia Tower Hotel, Barcelona, Spain At the 6th European Bioanalysis Forum Open Meeting, held from 20-22 November 2013 in Hesperia Tower Hotel, Barcelona, Spain, bioanalytical experts from pharmaceutical industry, academia, contract laboratories and regulatory bodies discussed current topics of interest in bioanalysis. 450 delegates from more than 170 institutes and companies participated in 75 open and stimulating presentations regarding the new US FDA Guidance for industry, technology updates, including liquid chromatography-mass spectrometry of proteins and antibody-drug conjugates, dried blood spots, sampling and extraction and regulatory aspects of, for example, flow cytometry, parallelism, and interferences in ligand-binding assays. This article aims to provide an overview of the highlights discussed at the meeting.
Du, Mingjie
2010-01-01
This paper aims to investigate the influential factors of Chinese young consumers’ rent-versus-buy housing decisions before marriage, and thus to explain why most Chinese consumers prefer housing ownership to renting or even regard an own-occupied housing as a prerequisite of marriage. The research was based on rich literatures concerning rent-versus-buy housing decisions and consumer decision making theory. A qualitative approach was adopted to conduct the research to gain in-depth insight o...
Improving safety of teenage and young adult drivers in Kansas.
2013-12-01
Statistics show that young drivers have higher motor vehicle crash rates compared to other age groups. This study investigated : characteristics, contributory causes, and factors which increase injury severity of young driver crashes in Kansas by com...
Empowering young people/ young adults to action
DEFF Research Database (Denmark)
Brander, Birgitte Gade
Research questions: How do the young students relate to their community? How do young students position themselves as agents in their own lives and in the places they live – which discourse is used?......Research questions: How do the young students relate to their community? How do young students position themselves as agents in their own lives and in the places they live – which discourse is used?...
Le Prevost, Marthe; Arenas-Pinto, Alejandro; Melvin, Diane; Parrott, Francesca; Foster, Caroline; Ford, Deborah; Evangeli, Michael; Winston, Alan; Sturgeon, Kate; Rowson, Katie; Gibb, Diana M; Judd, Ali
2018-03-04
Adolescents with perinatal HIV (PHIV) may be at higher risk of anxiety and depression than HIV negative young people. We investigated prevalence of anxiety and depression symptoms in 283 PHIV and 96 HIV-affected (HIV-negative) young people in England recruited into the Adolescents and Adults Living with Perinatal HIV (AALPHI) cohort. We used Hospital Anxiety and Depression Scale (HADS) scores and linear regression investigated predictors of higher (worse) scores.115 (41%) and 29 (30%) PHIV and HIV-affected young people were male, median age was 16 [interquartile range 15,18] and 16 [14,18] years and 241 (85%) and 71 (74%) were black African, respectively. There were no differences in anxiety and depression scores between PHIV and HIV-affected participants. Predictors of higher anxiety scores were a higher number of carers in childhood, speaking a language other than English at home, lower self-esteem, ever thinking life was not worth living and lower social functioning. Predictors of higher depression scores were male sex, death of one/both parents, school exclusion, lower self-esteem and lower social functioning. In conclusion, HIV status was not associated with anxiety or depression scores, but findings highlight the need to identify and support young people at higher risk of anxiety and depression..
Age at Immigration and Educational Attainment of Young Immigrants
van Ours, J.C.; Veenman, J.M.C.
2005-01-01
For immigrants who arrive in a country at a young age it is easier to assimilate than for teenagers.This paper investigates up to what immigration age the educational attainment of young immigrants in the Netherlands is similar to the educational attainment of secondgeneration immigrants, who were
E-inclusion: Digital equality - young people with disabilities.
Hemmingsson, H; Bolic-Baric, V; Lidström, H
2015-01-01
The United Nations' position is that digital access is a matter involving equality between groups of people, the securing of democratic rights, and equal opportunities for all citizens. This study investigates digital equality in school and leisure between young people with and without disabilities. A cross-sectional design with group comparisons was applied. Participants were young people (10-18 years of age) with disabilities (n=389) and a reference group in about the same ages. Data were collected by a survey focusing on access to and engagement in ICT activities in school and during leisure time. The results demonstrated young people with disabilities had restricted participation in computer use in educational activities, in comparison to young people in general. During leisure time young people with disabilities had a leading position compared to the reference group with respect to internet use in a variety of activities. Beneficial environmental conditions at home (and the reverse in schools) are discussed as parts of the explanation for the differing engagement levels at home and in school, and among young people with disabilities and young people in general. Schools need to prioritise use of ICT by young people with disabilities.
Post-stroke epilepsy in young adults: a long-term follow-up study
Arntz, R.M.; Rutten-Jacobs, L.C.A.; Maaijwee, N.A.M.M.; Schoonderwaldt, H.C.; Dorresteijn, L.D.A.; Dijk, E.J. van; Leeuw, F.E. de
2013-01-01
BACKGROUND: Little is known about the incidence and risk of seizures after stroke in young adults. Especially in the young seizures might dramatically influence prognosis and quality of life. We therefore investigated the long-term incidence and risk of post-stroke epilepsy in young adults with a
SunBlock '99: Young Scientists Investigate the Sun
Walsh, R. W.; Pike, C. D.; Mason, H.; Young, P.; Ireland, J.; Galsgaard, K.
1999-10-01
SunBlock `99 is a Web-based Public Understanding of Science and educational project which seeks to present the very latest solar research as seen through the eyes of young British scientists. These ``solar guides'' discuss not only their scientific interests, but also their extra-curricular activities and the reasons they chose scientific careers; in other words the human face of scientific research. The SunBlock '99 pages gather a range of solar images and movies from current solar space observatories and discuss the underlying physics and its relationship to the school curriculum. The instructional level is pitched at UK secondary school children (aged 13-16 years). It is intended that the material should not only provide a visually appealing introduction to the study of the Sun, but that it should help bridge the often wide gap between classroom science lessons and the research scientist `out in the field'. SunBlock '99 is managed by a team from the Rutherford Appleton Laboratory and the Universities of St Andrews and Cambridge, together with educational consultants. The production has, in part, been sponsored by PPARC and the Millennium Mathematics Project. Web site addresss: http://www.sunblock99.org.uk
ASSESSMENT OF THE PREVALENCE OF PSYCHIATRIC-DISORDER IN YOUNG-ADULTS
FERDINAND, RF; VANDERREIJDEN, M; VERHULST, FC; NIENHUIS, FJ; GIEL, R
Background. The effectiveness of different assessment procedures for determining prevalence rates of psychiatric disorder in young adults was investigated. Method. In a two-stage multi-method procedure, the Young Adult Self-Report, the Schedules for Clinical Assessment in Neuropsychiatry (SCAN), the
LENUS (Irish Health Repository)
Rolfs, Arndt
2011-01-01
Stroke in the young has not been thoroughly investigated with most previous studies based on a small number of patients from single centers. Furthermore, recent reports indicate that Fabry disease may be a significant cause for young stroke. The primary aim of our study was to determine the prevalence of Fabry disease in young stroke patients, while the secondary aim was to describe patterns of stroke in young patients.
Bavli, Özhan
2016-01-01
The aim of this study was to investigate the effects of eight weeks of step aerobic exercises on static balance, flexibility and selected basketball skills in young basketball players. A total of 20 basketball players (average age 16.1 ± 0.7 years and average sporting age 4.1 ± 0.7 years) voluntarily joined the study. Participants were randomly…
Young People, Pornography, and Sexuality: Sources and Attitudes
Wallmyr, Gudrun; Welin, Catharina
2006-01-01
The purpose of this study was to investigate the use of and attitudes among young people toward pornography and their sources of information about sexuality. Eight hundred and seventy-six young people ages 15-25 years (555 females and 321 males) who visited a youth center in Sweden for a period of 1 year answered a questionnaire about their use of…
Talking violence, constructing identities : young men in institutional care
Andersson, Kjerstin
2008-01-01
The aim of the study is to investigate how young men constructing identities in talk about their own use of violence. The study is based on a fieldwork at a youth detention home in Sweden. The data consists of individual interviews and video recordings of the treatment programme Aggression Replacement Training (ART). Detailed analyses have been made of conversations between the young men, between the young men and the trainers, and of the narratives generated in the individual interviews. The...
Talking Violence, Constructing Identity : Young Men in Institutional Care
Andersson, Kjerstin
2008-01-01
The aim of the study is to investigate how young men constructing identities in talk about their own use of violence. The study is based on a fieldwork at a youth detention home in Sweden. The data consists of individual interviews and video recordings of the treatment programme Aggression Replacement Training (ART). Detailed analyses have been made of conversations between the young men, between the young men and the trainers, and of the narratives generated in the individual interviews. The...
Hutchings, Jade N; Gannon, Theresa A; Gilchrist, Elizabeth
2010-04-01
A new pictorial assessment was developed to measure aggression-supportive cognitions among young aggressive male students. The assessment was comprised of 17 watercolor ambiguous sketches that could be interpreted in either an aggressive or a benign manner (e.g., two young people facing each other with their arms folded). The results showed that high trait aggressive male students were more likely to make hostile attributions of the pictures, providing significantly more themes of entitlement and power in the stories they generated about the pictures. Aggressive male students also endorsed significantly more aggression-supportive cognitions on a self-report measure and provided some supporting qualitative accounts of physically aggressive encounters. The results of this study are discussed and evaluated with reference to future work with young violent adolescents.
Directory of Open Access Journals (Sweden)
Viktoriia Tsuber
Full Text Available Psychosocial stress has been long known to have deleterious effects on health. Nevertheless, an exposure to moderate stressors enhances resilience and promotes health benefits. Male and female organisms differ in many aspects of health and disease. The aim of this study was to investigate antioxidant activity and oxidative damage in saliva in a psychosocial stress paradigm in men and women. Here, we show that an acute stressor of moderate strength augments antioxidant activity and decreases oxidative damage in whole saliva of young people. An examination stress caused a significant increase of catalase activity, accompanied by a decrease of levels of oxidized proteins. Levels of thiobarbituric acid-reacting substances did not increase at stress, indicating that lipid peroxidation was not activated. The stress-induced alterations were more manifested in young women compared to young men. Thus, antioxidant protective mechanisms are more activated by a moderate stressor in young women than in young men.
Tsuber, Viktoriia; Kadamov, Yunus; Tarasenko, Lydia
2014-01-01
Psychosocial stress has been long known to have deleterious effects on health. Nevertheless, an exposure to moderate stressors enhances resilience and promotes health benefits. Male and female organisms differ in many aspects of health and disease. The aim of this study was to investigate antioxidant activity and oxidative damage in saliva in a psychosocial stress paradigm in men and women. Here, we show that an acute stressor of moderate strength augments antioxidant activity and decreases oxidative damage in whole saliva of young people. An examination stress caused a significant increase of catalase activity, accompanied by a decrease of levels of oxidized proteins. Levels of thiobarbituric acid-reacting substances did not increase at stress, indicating that lipid peroxidation was not activated. The stress-induced alterations were more manifested in young women compared to young men. Thus, antioxidant protective mechanisms are more activated by a moderate stressor in young women than in young men.
What Do Young People Today Really Think about Jesus?
Walshe, Karen
2005-01-01
This article presents the key findings of a recent study investigating young people's knowledge and understanding of Jesus and demonstrates how young people today appear to be experiencing the same difficulties when engaging with the figure of Jesus in the religious education classroom as they did almost 40 years ago. It concludes by suggesting…
Young Learner Perspectives on Four Focus-on-Form Tasks
Shak, Juliana; Gardner, Sheena
2008-01-01
Recent studies suggest that focus-on-form (FonF) instruction has a positive effect on the second language proficiency of young learners. However, few have looked at learner perspectives on different FonF tasks, particularly in those young learners. This study investigates children's attitudes towards four FonF task-types in three Primary 5 English…
Young People Smokers’ Reactions on Peer Influence Not to Smoke
Harakeh, Z.; van Nijnatten, C.H.C.J.
2016-01-01
Background: Peers exert influence not to smoke but little is yet known on how this affects young people's behavior and cognitions. Objectives: This experimental study investigates the impact of two types of peer influence not to smoke on the verbalized attitudes and responses of daily-smoking young
The Longitudinal Impact of Adolescent Drug Use on Socioeconomic Outcomes in Young Adulthood
Broman, Clifford L.
2009-01-01
This study investigates how drug use in adolescence contributes to socioeconomic outcomes in young adulthood. Several studies have investigated whether drug problems alter the life course in ways that are detrimental to young adult achievement, but findings are inconsistent. We use data from the National Longitudinal Study of Adolescent Health to…
Proactive coping and gambling disorder among young men.
Sleczka, Pawel; Braun, Barbara; Grüne, Bettina; Bühringer, Gerhard; Kraus, Ludwig
2016-12-01
Objectives Male sex, young age, and frequent gambling are considered as risk factors for gambling disorder (GD) and stress might be one of the triggers of gambling behavior among problem gamblers. Conversely, well-developed coping with stress might counteract gambling problems. The Proactive Coping Theory provides a promising approach for the further development of preventive and treatment measures. The objective of the study was to investigate different facets of proactive coping (PC) in young male gamblers. Methods Young men from Bavaria were recruited via the Munich citizens' registry (n = 2,588) and Facebook invitations (n = 105). In total, 173 out of 398 individuals were positively screened for frequent gambling and/or signs of related problems and completed the baseline questionnaire of the Munich Leisure-time Study. Factors investigated include gambling problems, PC, impulsiveness, social support, and psychological distress. Results Gambling problems were associated with lower levels of preventive coping as well as of adaptive reaction delay. The associations were also significant when controlled for impulsiveness and general psychological distress. Preventive coping moderated the association between social support and gambling problems. Discussion and conclusions Young men with gambling problems less frequently prevent the occurrence of stressors and more often react hasty when these occur. While the investigated group reported good social support, this factor was negatively associated with GD only among individuals with good preventive coping. Preventive coping poses a useful construct for selective prevention and treatment as it can be modified in professional interventions.
No excess fatigue in young adult survivors of childhood cancer
Langeveld, N. E.; Grootenhuis, M. A.; Voûte, P. A.; de Haan, R. J.; van den Bos, C.
2003-01-01
Clinical reports suggest that many survivors of childhood cancer experience fatigue as a long-term effect of their treatment. To investigate this issue further, we assessed the level of fatigue in young adult survivors of childhood cancer. We compared the results with a group of young adults with no
A concept analysis of young adults; Perception of HIV Counselling and Testing
Patrone R. Risenga; Mashudu Davhana-Maselesele
2017-01-01
Aim: The aim of the study was to investigate perceptions of young adults regarding HIV Counselling and Testing (HCT) and the factors contributing to either negative or positive perceptions towards the programme. This article is a report of a concept analysis of young adults' perceptions of HCT that were collected during the study. Background: Perception forms the core of HIV Counselling and Testing (HCT) use by young adults, because it is from these perceptions that young adults will decid...
Energy Technology Data Exchange (ETDEWEB)
Wiley, H. S.
2009-11-01
There has been much concern about the impact of tight funding on the careers of young scientists. When only a small percentage of grants are approved, even the smallest problem or error with an application can push it out of the funding range. Unfortunately, the relative lack of grant writing skills by new investigators often has this effect. To avoid a situation where only experienced investigators with polished writing skills are funded, the National Institutes of Health has instituted a more generous ranking scale for new investigators. Not surprisingly, some senior investigators have protested, calling it reverse discrimination. I say that their anger is misplaced. New investigators do deserve a break.
Gudjonsson, Gisli H; Sigurdsson, Jon Fridrik; Sigfusdottir, Inga Dora; Asgeirsdottir, Bryndis Bjork; González, Rafael A; Young, Susan
2016-03-01
The principal aims of this study are to identify risk factors associated with police arrest and false confessions and to investigate whether the severity of the ADHD condition/symptoms increases the risk. 22,226 young persons in Iceland anonymously completed self-report questionnaires screening for conduct disorder and ADHD. In addition, they stated whether they had a diagnosis of ADHD and had received ADHD medication, and their history of offending, police interrogation and false confession. Participants were stratified into two age groups, 14-16 and 17-24 years. The older group was significantly more likely to have been interrogated by the police but the younger group were much more vulnerable to false confession during interrogation. Males were more likely to be at risk for both than females. The severity of the ADHD condition increased the risk of both interrogation and false confession. Negative binomial regressions showed that age, gender, conduct disorder, offending, and ADHD symptoms were all significant predictors of both interrogations and number of false confessions. Conduct disorder was the single best predictor of police interrogation, but the findings were more mixed regarding false confessions. Young people presenting with a combination of severe ADHD and comorbid conduct disorder had the worst outcome for both interrogation and false confessions. The findings endorse the need for support of persons with ADHD to be put in place to ensure fair due process and to prevent miscarriages of justice.
Directory of Open Access Journals (Sweden)
Sylvia Söderström
2013-05-01
Full Text Available Norwegian authorities’ policy aims at securing an information society for all, emphasizing the importance of accessible and usable Information and Communication Technology (ICT for everyone. While the body of research on young people’s use of ICT is quite comprehensive, research addressing digital differentiation in young people with disabilities’ use of ICT is still in its early days. This article investigates how young people with disabilities’ use, or non-use, of assistive ICT creates digital differentiations. The investigation elaborates on how the anticipations and stereotypes of disability establish an authoritative definition of assistive ICT, and the consequence this creates for the use of the Web by young people with disabilities. The object of the article is to provide enhanced insight into the field of technology and disability by illuminating how assistive ICT sometimes eliminates and sometimes reproduces stereotypes and digital differentiations. The investigation draws on a qualitative interview study with 23 young Norwegians with disabilities, aged 15–20 years. I draw on a theoretical perspective to analyze the findings of the study, which employs the concept of identity multiplicity. The article’s closing discussion expands on technology’s significance in young people’s negotiations of impairment and of perceptions of disability
Well Researched, Yet Little Understood: Young Adults and Physical Activity
Cothran, Donetta; Kulinna, Pamela Hodges
2005-01-01
The authors present two beginning studies. One investigated the teaching-style preferences of young adults, and the other looked at physical activity trends within this age group. One key to understanding young adults and physical activity is to recognize the importance of participant cognition on physical activity patterns. From this…
Medvedovici, Andrei; Udrescu, Stefan; Albu, Florin; Tache, Florentin; David, Victor
2011-09-01
Liquid-liquid extraction of target compounds from biological matrices followed by the injection of a large volume from the organic layer into the chromatographic column operated under reversed-phase (RP) conditions would successfully combine the selectivity and the straightforward character of the procedure in order to enhance sensitivity, compared with the usual approach of involving solvent evaporation and residue re-dissolution. Large-volume injection of samples in diluents that are not miscible with the mobile phase was recently introduced in chromatographic practice. The risk of random errors produced during the manipulation of samples is also substantially reduced. A bioanalytical method designed for the bioequivalence of fenspiride containing pharmaceutical formulations was based on a sample preparation procedure involving extraction of the target analyte and the internal standard (trimetazidine) from alkalinized plasma samples in 1-octanol. A volume of 75 µl from the octanol layer was directly injected on a Zorbax SB C18 Rapid Resolution, 50 mm length × 4.6 mm internal diameter × 1.8 µm particle size column, with the RP separation being carried out under gradient elution conditions. Detection was made through positive ESI and MS/MS. Aspects related to method development and validation are discussed. The bioanalytical method was successfully applied to assess bioequivalence of a modified release pharmaceutical formulation containing 80 mg fenspiride hydrochloride during two different studies carried out as single-dose administration under fasting and fed conditions (four arms), and multiple doses administration, respectively. The quality attributes assigned to the bioanalytical method, as resulting from its application to the bioequivalence studies, are highlighted and fully demonstrate that sample preparation based on large-volume injection of immiscible diluents has an increased potential for application in bioanalysis.
Lebanese Young Citizens’ Attitudes toward Peace and Democracy
Directory of Open Access Journals (Sweden)
Khayrazad Kari Jabbour
2013-12-01
Full Text Available Lebanon is a small democratic country with a population of less than four million and a range of diversity; there are at least 18 different religious sects and 19 different political parties. The diversity among ethnic, religious and/or political groups has created conflicts that severely impact the Lebanese economy, environment, politics and most importance our young citizens. The aim of this investigation is to capture students’ awareness and attitudes toward the accountability and mechanisms of peace and democracy. Data for the study was obtained from extensive literature reviews and questionnaire surveys of 70 high school students. The investigation was conducted in the fall of the year 2013. The results of the study showed that most Lebanese young citizen view peace and democracy process associated with the end of violence and conflict behaviors; very small percent of respondents believe that bringing peace and democracy process should be answered by the people or by themselves. Results also indicate a lack of a sense of security among young citizen. This raises the urgent need to put into practice an effective peace education program that inspires and motivates young citizens to be involved in the peace and the democracy building process.
The State of Young Adults’ Balance Sheets: Evidence from the Survey of Consumer Finances
Dettling, Lisa J.; Hsu, Joanne W.
2014-01-01
The authors investigate recent trends in the financial circumstances of young adults using data from the triennial Survey of Consumer Finances (SCF) from 2001 to 2013. They examine trends in young adults’ net worth, break down the composition into specific assets and liabilities, and describe young adults’ experiences with credit markets. The analysis focuses on three main comparisons: (i) trends over time (ii) between young adults and older adults and (iii) between young adults in 2013 (memb...
Differences in investigations of sudden unexpected deaths in young people in a nationwide setting
DEFF Research Database (Denmark)
Winkel, Bo Gregers; Holst, Anders Gaarsdal; Theilade, Juliane
2012-01-01
BACKGROUND: Inherited disease may be causative in many young sudden unexpected death cases. Autopsy is essential in the counselling of the bereaved, as the family of the victim may be at risk too. In a nationwide setting operating under the same set of laws, we hypothesized that regional differen...
Young Stellar Objects from Soft to Hard X-rays
Güdel, Manuel
2009-05-01
Magnetically active stars are the sites of efficient particle acceleration and plasma heating, processes that have been studied in detail in the solar corona. Investigation of such processes in young stellar objects is much more challenging due to various absorption processes. There is, however, evidence for violent magnetic energy release in very young stellar objects. The impact on young stellar environments (e.g., circumstellar disk heating and ionization, operation of chemical networks, photoevaporation) may be substantial. Hard X-ray devices like those carried on Simbol-X will establish a basis for detailed studies of these processes.
On the Role of Educational Factors in the Development of Danish Young Learners’ EFL Proficiency
DEFF Research Database (Denmark)
Aus der Wieschen, Maria Vanessa
The study investigates how the quantity and quality of exposure to English in Danish primary schools influences Young Learners’ English language learning.......The study investigates how the quantity and quality of exposure to English in Danish primary schools influences Young Learners’ English language learning....
Photoelectrochemical enzymatic biosensors.
Zhao, Wei-Wei; Xu, Jing-Juan; Chen, Hong-Yuan
2017-06-15
Enzymatic biosensors have been valuable bioanalytical devices for analysis of diverse targets in disease diagnosis, biological and biomedical research, etc. Photoelectrochemical (PEC) bioanalysis is a recently emerged method that promptly becoming a subject of new research interests due to its attractive potential for future bioanalysis with high sensitivity and specificity. PEC enzymatic biosensors integrate the inherent sensitivities of PEC bioanalysis and the selectivity of enzymes and thus share their both advantages. Currently, PEC enzymatic biosensors have become a hot topic of significant research and the recent impetus has grown rapidly as demonstrated by increased research papers. Given the pace of advances in this area, this review will make a thorough discussion and survey on the fundamentals, sensing strategies, applications and the state of the art in PEC enzymatic biosensors, followed by future prospects based on our own opinions. We hope this work could provide an accessible introduction to PEC enzymatic biosensors for any scientist. Copyright © 2016 Elsevier B.V. All rights reserved.
Automated dried blood spots standard and QC sample preparation using a robotic liquid handler.
Yuan, Long; Zhang, Duxi; Aubry, Anne-Francoise; Arnold, Mark E
2012-12-01
A dried blood spot (DBS) bioanalysis assay involves many steps, such as the preparation of standard (STD) and QC samples in blood, the spotting onto DBS cards, and the cutting-out of the spots. These steps are labor intensive and time consuming if done manually, which, therefore, makes automation very desirable in DBS bioanalysis. A robotic liquid handler was successfully applied to the preparation of STD and QC samples in blood and to spot the blood samples onto DBS cards using buspirone as the model compound. This automated preparation was demonstrated to be accurate and consistent. However the accuracy and precision of automated preparation were similar to those from manual preparation. The effect of spotting volume on accuracy was evaluated and a trend of increasing concentrations of buspirone with increasing spotting volumes was observed. The automated STD and QC sample preparation process significantly improved the efficiency, robustness and safety of DBS bioanalysis.
Siriphorn, Akkradate; Chamonchant, Dannaovarat
2015-01-01
[Purpose] The potential health benefits of the Nintendo Wii balance board exercise have been widely investigated. However, no study has been conducted to examine the benefits of Wii exercise for overweight young adults. The aim of this study was to investigate the effect of exercise performed on a Nintendo Wii balance board on the balance and lower limb muscle strength in overweight young adults. [Subjects and Methods] Within-subject repeated measures analysis was used. Sixteen young adults (...
Nakata-Yamada, Kayo; Inoue, Masami; Ioka, Akiko; Ito, Yuri; Tabuchi, Takahiro; Miyashiro, Isao; Masaie, Hiroaki; Ishikawa, Jun; Hino, Masayuki; Tsukuma, Hideaki
2016-01-01
The survival gap between adolescents and young adults (AYAs) with hematological malignancies persists in many countries. To determine to what extent it does in Japan, we investigated survival and treatment regimens in 211 Japanese AYAs (15-29 years) in the Osaka Cancer Registry diagnosed during 2001-2005 with hematological malignancies, and compared adolescents (15-19 years) with young adults (20-29 years). AYAs with acute lymphoblastic leukemia (ALL) had a poor 5-year survival (44%), particularly young adults (29% vs. 64% in adolescents, p = 0.01). Additional investigation for patients with ALL revealed that only 19% of young adults were treated with pediatric treatment regimens compared with 45% of adolescents (p = 0.05). Our data indicate that we need to focus on young adults with ALL and to consider establishing appropriate cancer care system and guidelines for them in Japan.
The Prevalence of food hypersensitivity in young adults
DEFF Research Database (Denmark)
Østerballe, Morten; Mørtz, Charlotte G; Hansen, Tine Kjær
2009-01-01
by questionnaire, skin prick test (SPT) and histamin release (HR) followed by oral challenge to the most common allergenic foods. FHS was divided into primary and secondary FHS. Primary FHS was defined as being independent of pollen sensitization, whereas secondary FHS was defined as reactions to pollen related......Osterballe M, Mortz CG, Hansen TK, Andersen KE, Bindslev-Jensen C. The Prevalence of food hypersensitivity in young adults. Pediatr Allergy Immunol 2009. (c) 2009 The Authors Journal compilation (c) 2009 John Wiley & Sons A/SA rising prevalence of food hypersensitivity (FHS) and severe allergic...... reactions to foods have been reported in the last decade. However, little is known on the prevalence in young adults. This study estimated the prevalence of FHS to the most common allergenic foods in an unselected population of young adults. We investigated a cohort of 1272 young adults 22 years of age...
Aiming and clicking in young children's use of the computer mouse
Donker, A.; Reitsma, P.
2007-01-01
The present study investigated the abilities of young children to aim and click with a computer mouse. Young children have not yet fully developed their motor skills and they are therefore more likely than adults to click next to targets on the computer screen. Because in educational software
Genetics of ischaemic stroke in young adults
Directory of Open Access Journals (Sweden)
Eva Terni
2015-06-01
General significance: This review focuses on the main causes of genetically-based ischemic stroke in young adults, often classified as indeterminate, investigating also the recent findings of the GWAS, in order to improve diagnostic and therapeutic management.
Flavored e-cigarette use: Characterizing youth, young adult, and adult users
Harrell, M.B.; Weaver, S.R.; Loukas, A.; Creamer, M.; Marti, C.N.; Jackson, C.D.; Heath, J.W.; Nayak, P.; Perry, C.L.; Pechacek, T.F.; Eriksen, M.P.
2016-01-01
The purpose of this study is to investigate how the use of flavored e-cigarettes varies between youth (12?17?years old), young adults (18?29?years old), and older adults (30?+ years old). Cross-sectional surveys of school-going youth (n?=?3907) and young adult college students (n?=?5482) in Texas, and young adults and older adults (n?=?6051) nationwide were administered in 2014?2015. Proportions and 95% confidence intervals were used to describe the percentage of e-cigarette use at initiation...
Veldman, Karin; Reijneveld, Sijmen A; Ortiz, Josue Almansa; Verhulst, Frank C; Bültmann, Ute
2015-06-01
Young adults at work without basic educational level (BEL), and young adults in Neither Employment, Education nor Training (NEET) are at high risk of adverse employment outcomes. Evidence lacks on the impact of mental health problems during childhood, adolescence and young adulthood on employment outcomes of young adults. Therefore, the aims of this study were to (1) identify trajectories of mental health problems from childhood to young adulthood and (2) investigate the relation between these trajectories and the educational or employment status of young adults. Data were used from the Tracking Adolescents' Individual Lives Survey (TRAILS), a Dutch prospective cohort study with 9-year follow-up. Trajectories of mental health problems measured at ages 11, 13.5, 16 and 19 years were identified in 1711 young adults with latent class growth models. Young adults with high-stable trajectories of total problems, from childhood to young adulthood, were more likely to work without BEL or be in NEET at age 19, than to be at school or to work with BEL (28.0% vs 16.0%, p=0.01). The same was found for externalising problems (35.3% vs 23.2%, p=0.02). For internalising and attention problems, no statistically significant differences were found. Young adults with high-stable trajectories of mental health problems from age 11 to 19, were at risk of adverse employment outcomes. Interventions reducing mental health problems in childhood may improve the educational or employment status of young adults and their chances for successfully entering the labour market. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Prosocial behaviours of young adolescents: a focus group study.
Bergin, Christi; Talley, Susan; Hamer, Lynne
2003-02-01
This study investigated young adolescents' perceptions of their peers' prosocial behaviours. In eight focus groups, 53 11- to 13-year olds described specific prosocial acts of their peers. Results suggest that traditional research has not addressed the diversity of prosocial behaviours that youth enact, nor emphasized behaviours that are salient to young adolescents. Such behaviours included standing up for others, encouraging others, helping others develop skills, including others who are left out, and being humorous. Facilitating emotional regulation of others emerged as an important component of prosocial behaviour. These data can help guide future research on prosocial development to include a broader array of authentic behaviours of young adolescents.
The 10th Annual Bioassays and Bioanalytical Method Development Conference.
Ma, Mark; Tudan, Christopher; Koltchev, Dolly
2015-01-01
The 10th Annual Bioassays and Bioanalytical Method Development Conference was hosted in Boston, MA, USA on 20-22 October 2014. This meeting brought together scientists from the biopharmaceutical and life sciences industries, the regulatory agency and academia to share and discuss current trends in cell-based assays and bioanalysis, challenges and ideas for the future of the bioassays and bioanalytical method development. The experiences associated with new and innovative technologies were evaluated as well as their impact on the current bioassays methodologies and bioanalysis workflow, including quality, feasibility, outsourcing strategies and challenges, productivity and compliance. Several presentations were also provided by members of the US FDA, sharing both scientific and regulatory paradigms including a most recent update on the position of the FDA with specific aspects of the draft Bioanalytical Method Validation guidance following its review of the industry's responses. The meeting was jointly coincided with the 15th Annual Immunogenicity for Biotherapeutics meeting, allowing for attendees to also familiarize themselves with new and emerging approaches to overcome the effect of immunogenicity, in addition to investigative strategies.
Interactions between exoplanets and the winds of young stars
Directory of Open Access Journals (Sweden)
Vidotto A. A.
2014-01-01
Full Text Available The topology of the magnetic field of young stars is important not only for the investigation of magnetospheric accretion, but also responsible in shaping the large-scale structure of stellar winds, which are crucial for regulating the rotation evolution of stars. Because winds of young stars are believed to have enhanced mass-loss rates compared to those of cool, main-sequence stars, the interaction of winds with newborn exoplanets might affect the early evolution of planetary systems. This interaction can also give rise to observational signatures which could be used as a way to detect young planets, while simultaneously probing for the presence of their still elusive magnetic fields. Here, we investigate the interaction between winds of young stars and hypothetical planets. For that, we model the stellar winds by means of 3D numerical magnetohydrodynamic simulations. Although these models adopt simplified topologies of the stellar magnetic field (dipolar fields that are misaligned with the rotation axis of the star, we show that asymmetric field topologies can lead to an enhancement of the stellar wind power, resulting not only in an enhancement of angular momentum losses, but also intensifying and rotationally modulating the wind interactions with exoplanets.
HOW DO YOUNG PEOPLE SELECT INFORMATION TO PLAN A TRIP
Directory of Open Access Journals (Sweden)
Oana ŢUGULEA
2013-12-01
Full Text Available The purpose of the research is to reveal the young tourists preferences in the process of planning a trip. Sources of information used, the utility of Internet/travel agencies in planning travel trip activities, preferred means of transportation and types of accommodation are investigated. As research methods, there used both qualitative and quantitative methods: focus group and survey. Internet is more used by young tourists in planning trips than travel agencies are. Internet is considered more useful in the documentation stage and when buying airline tickets. Young tourists are more influenced by friends when planning a trip. Young tourists prefer cars and planes as means of transportation for a trip and hotels and guesthouses as accommodation when traveling.
Q-methodology to identify young adult renal transplant recipients at risk for nonadherence
M. Moors-Tielen (Mirjam); A.L. van Staa (AnneLoes); S. Jedeloo (Susan); N.J.A. van Exel (Job); W. Weimar (Willem)
2008-01-01
textabstractBACKGROUND. Young adult renal transplant recipients may display patterns of behavior that affect graft survival. The present study aimed to identify young adults at risk for nonadherent behavior by investigating their attitudes about posttransplant health lifestyle. METHOD. A
Investigating the drinking patterns of young people over the course of the evening at weekends
Kuntsche, E.N.; Labhart, F.
2012-01-01
Background Memory deficits lead to distortion when long recall periods are used to assess alcohol consumption. We used the recently developed Internet-based cell phone-optimised assessment technique (ICAT) to describe the drinking patterns of young people over the course of Thursday, Friday and
Driving Cultures: Cars, Young People and Cultural Research
Directory of Open Access Journals (Sweden)
Sarah Redshaw
2011-11-01
Full Text Available This article describes the Driving Cultures research, the cultural importance of the car and the psychological approaches central to research in the field of road safety and investigations of the over–representation of young people in crashes. The aim of the article is to outline driving as a cultural practice drawing on the experiences of young people as described in focus groups in order to show how cultural research can contribute to a social concern such as traffic injury and death.
Pound, Pandora; Langford, Rebecca; Campbell, Rona
2016-09-13
Although sex and relationship education (SRE) represents a key strand in policies to safeguard young people and improve their sexual health, it currently lacks statutory status, government guidance is outdated and a third of UK schools has poor-quality SRE. We aimed to investigate whether current provision meets young people's needs. Synthesis of qualitative studies of young people's views of their school-based SRE. Eligible studies originated from the UK, Ireland, the USA, Australia, New Zealand, Canada, Japan, Iran, Brazil and Sweden. Studies of students aged 4-19 in full-time education, young adults ≤19 (not necessarily in full-time education) or adults ≤25 if recalling their experiences of school-based SRE. -69 publications were identified, with 55 remaining after quality appraisal (representing 48 studies). The synthesis found that although sex is a potent and potentially embarrassing topic, schools appear reluctant to acknowledge this and attempt to teach SRE in the same way as other subjects. Young people report feeling vulnerable in SRE, with young men anxious to conceal sexual ignorance and young women risking sexual harassment if they participate. Schools appear to have difficulty accepting that some young people are sexually active, leading to SRE that is out of touch with many young people's lives. Young people report that SRE can be negative, gendered and heterosexist. They expressed dislike of their own teachers delivering SRE due to blurred boundaries, lack of anonymity, embarrassment and poor training. SRE should be 'sex-positive' and delivered by experts who maintain clear boundaries with students. Schools should acknowledge that sex is a special subject with unique challenges, as well as the fact and range of young people's sexual activity, otherwise young people will continue to disengage from SRE and opportunities for safeguarding and improving their sexual health will be reduced. Published by the BMJ Publishing Group Limited. For permission
Halkitis, Perry N; Kapadia, Farzana; Bub, Kristen L; Barton, Staci; Moreira, Alvaro D; Stults, Christopher B
2015-06-01
The persistence of disparities in STI/HIV risk among a new generation of emerging adult gay, bisexual, and other men who have sex with men (YMSM) warrant holistic frameworks and new methodologies for investigating the behaviors related to STI/HIV in this group. In order to better understand the continued existence of these disparities in STI/HIV risk among YMSM, the present study evaluated the presence and persistence of syndemic conditions among YMSM by examining the co-occurrence of alcohol and drug use, unprotected sexual behavior, and mental health burden over time. Four waves of data, collected over the first 18 months of a 7 wave, 36-month prospective cohort study of YMSM (n=600) were used to examine the extent to which measurement models of drug use, unprotected sexual behavior, and mental health burden remained consistent across time using latent class modeling. Health challenges persisted across time as these YMSM emerged into young adulthood and the measurement models for the latent constructs of drug use and unprotected sexual behavior were essentially consistent across time whereas models for mental health burden varied over time. In addition to confirming the the robustness of our measurement models which capture a more holistic understandings of the health conditions of drug use, unprotected sex, and mental health burden, these findings underscore the ongoing health challenges YMSM face as they mature into young adulthood. These ongoing health challenges, which have been understood as forming a syndemic, persist over time, and add further evidence to support ongoing and vigilant comprehensive health programming for sexual minority men that move beyond a sole focus on HIV.
Children Explain the Rainbow: Using Young Children's Ideas to Guide Science Curricula
Siry, Christina; Kremer, Isabelle
2011-01-01
This study examines young children's ideas about natural science phenomena and explores possibilities in starting investigations in kindergarten from their ideas. Given the possibilities inherent in how young children make sense of their experiences, we believe it is critical to take children's perspectives into consideration when designing any…
Attitudes of Kuwaiti Young Adults toward Marriage and Divorce:
Directory of Open Access Journals (Sweden)
Humoud Alqashan
2010-03-01
Full Text Available This study investigates whether parental marital status affects young adults’ attitudes toward marriage and divorce. There exists a vast amount of literature on the impact of divorce on young adults in Western cultures; however, no previous empirical studies have been conducted on the attitudes of young adults from intact and divorced families in the Gulf region or in Arab countries in the Middle East. The sample of the study consisted of 661 young adults from Kuwait University (from divorced and intact families. The findings reveal that adults whose parents divorced show fewer positive attitudes toward marriage than do those individuals from intact marriages. The study also suggests that adults whose parents were divorced carry more positive attitudes toward divorce compared with individuals from intact marriages. Furthermore, gender was found to be an important factor in shaping attitudes toward marriage and divorce. A longitudinal study is recommended to look at the changes in young adults’ attitudes toward marriage and divorce over time, which will help to identify the influence of other factors of attitudes toward marriage and divorce.
Thyroid functions in young diabetics
International Nuclear Information System (INIS)
Hafiez, A.A.; Ismail, A.A.; Awadeen, M.R.; Abbas, E.Z.; Farag, M.S.A.
1982-01-01
Assessment of the thyroid-pituitary axis was performed in uncontrolled (20 cases) and controlled (22 cases) insulin-dependent young diabetics who were university students attending the university hospital. A third age-matching group (21 normal subjects) was also investigated. The plasma glucose level was determined after fasting as well as 2 hours after an oral glucose meal (50 g). Thyroxine (T 4 ), triiodeothyronine (T 3 ) and thyroid stimulating hormone (TSH) were assayed by RIA. The data obtained showed a lowered level of T 3 and T 4 and a raised level of TSH in uncontrolled young diabetics as compared to corresponding values for age matching normals. The group of controlled diabetics showed near normal T 3 and increased T 4 levels, but still lower than normal. TSH levels dropped significantly to the normal level. (author)
Young peoples’ access to working life in three Nordic countries
DEFF Research Database (Denmark)
Jørgensen, Christian Helms
2018-01-01
While working life in the Nordic countries generally has a high quality, the question examined in this chapter is how accessible working life is for young people. The chapter examines how upper secondary vocational education (VET) is connected to working life and how it supports young peoples......’ transitions to the labour market in Norway, Denmark and Sweden. The examination includes a conceptual discussion of the links between education and working life in comparative research on VET and transition systems. It explores how the VET systems match the educational demand of young people with the skills...... requirements in working life. In addition, it examines young peoples’ transitions to working life in two selected industries, health care and construction. Also, three new, innovative institutions to mediate between VET and working life are investigat-ed....
Young people's views of mental health education in secondary schools: a Scottish study.
Woolfson, R; Woolfson, L; Mooney, L; Bryce, D
2009-11-01
This exploratory study used mixed methods to investigate young people's preferences in the delivery of mental health education and to investigate possible age and gender differences. Information was gathered about the delivery of mental health education in three secondary schools. Nine pupil focus groups were carried out to identify key themes which were then further developed and administered through questionnaires to a larger sample of 773 pupils. Gender and age differences were found in young people's preferences about who should deliver mental health education, and what, when, where and how this should be delivered. Mental health education should reflect the needs of young people. Age and gender preferences should be considered when designing these programmes.
Sünram-Lea, Sandra I; Owen, Lauren; Finnegan, Yvonne; Hu, Henglong
2011-08-01
It has been suggested that the memory enhancing effect of glucose follows an inverted U-shaped curve, with 25 g resulting in optimal facilitation in healthy young adults. The aim of this study was to further investigate the dose dependency of the glucose facilitation effect in this population across different memory domains and to assess moderation by interindividual differences in glucose regulation and weight. Following a double-blind, repeated measures design, 30 participants were administered drinks containing five different doses of glucose (0 g, 15 g, 25 g, 50 g, and 60 g) and were tested across a range of memory tasks. Glycaemic response and changes in mood state were assessed following drink administration. Analysis of the data showed that glucose administration did not affect mood, but significant glucose facilitation of several memory tasks was observed. However, dose-response curves differed depending on the memory task with only performance on the long-term memory tasks adhering largely to the previously observed inverted U-shaped dose-response curve. Moderation of the response profiles by interindividual differences in glucose regulation and weight was observed. The current data suggest that dose-response function and optimal dose might depend on cognitive domain and are moderated by interindividual differences in glucose regulation and weight.
Life Course Stage in Young Adulthood and Intergenerational Congruence in Family Attitudes
Bucx, Freek; Raaijmakers, Quinten; van Wel, Frits
2010-01-01
We investigated how intergenerational congruence in family-related attitudes depends on life course stage in young adulthood. Recent data from the Netherlands Kinship Panel Study were used; the present sample included 2,041 dyads of young adults and their parents. Findings are discussed in terms of the elasticity in intergenerational attitude…
Australian Qualifications Framework Lower-Level Qualifications: Pathways to Where for Young People?
Stanwick, John
2005-01-01
This study investigates where certificate I and II qualifications lead young people aged 15-24 years in terms of employment and further study. A prime motivation for young people undertaking these qualifications is to facilitate transition into the labour market. These qualifications are aimed at developing basic vocational skills or preparatory…
Young Children's Responses to Guilt Displays
Vaish, Amrisha; Carpenter, Malinda; Tomasello, Michael
2011-01-01
Displaying guilt after a transgression serves to appease the victim and other group members, restore interpersonal relationships, and indicate the transgressors' awareness of and desire to conform to the group's norms. We investigated whether and when young children are sensitive to these functions of guilt displays. In Study 1, after 4- and…
Mapping brain development during childhood, adolescence and young adulthood
Guo, Xiaojuan; Jin, Zhen; Chen, Kewei; Peng, Danling; Li, Yao
2009-02-01
Using optimized voxel-based morphometry (VBM), this study systematically investigated the differences and similarities of brain structural changes during the early three developmental periods of human lives: childhood, adolescence and young adulthood. These brain changes were discussed in relationship to the corresponding cognitive function development during these three periods. Magnetic Resonance Imaging (MRI) data from 158 Chinese healthy children, adolescents and young adults, aged 7.26 to 22.80 years old, were included in this study. Using the customized brain template together with the gray matter/white matter/cerebrospinal fluid prior probability maps, we found that there were more age-related positive changes in the frontal lobe, less in hippocampus and amygdala during childhood, but more in bilateral hippocampus and amygdala and left fusiform gyrus during adolescence and young adulthood. There were more age-related negative changes near to central sulcus during childhood, but these changes extended to the frontal and parietal lobes, mainly in the parietal lobe, during adolescence and young adulthood, and more in the prefrontal lobe during young adulthood. So gray matter volume in the parietal lobe significantly decreased from childhood and continued to decrease till young adulthood. These findings may aid in understanding the age-related differences in cognitive function.
Ross, Veerle; Jongen, Ellen M M; Wang, Weixin; Brijs, Tom; Brijs, Kris; Ruiter, Robert A C; Wets, Geert
2014-01-01
Distracted driving has received increasing attention in the literature due to potential adverse safety outcomes. An often posed solution to alleviate distraction while driving is hands-free technology. Interference by distraction can occur however at the sensory input (e.g., visual) level, but also at the cognitive level where hands-free technology induces working memory (WM) load. Active maintenance of goal-directed behavior in the presence of distraction depends on WM capacity (i.e., Lavie's Load theory) which implies that people with higher WM capacity are less susceptible to distractor interference. This study investigated the interaction between verbal WM load and WM capacity on driving performance to determine whether individuals with higher WM capacity were less affected by verbal WM load, leading to a smaller deterioration of driving performance. Driving performance of 46 young novice drivers (17-25 years-old) was measured with the lane change task (LCT). Participants drove without and with verbal WM load of increasing complexity (auditory-verbal response N-back task). Both visuospatial and verbal WM capacity were investigated. Dependent measures were mean deviation in the lane change path (MDEV), lane change initiation (LCI) and percentage of correct lane changes (PCL). Driving experience was included as a covariate. Performance on each dependent measure deteriorated with increasing verbal WM load. Meanwhile, higher WM capacity related to better LCT performance. Finally, for LCI and PCL, participants with higher verbal WM capacity were influenced less by verbal WM load. These findings entail that completely eliminating distraction is necessary to minimize crash risks among young novice drivers. Copyright © 2013 Elsevier Ltd. All rights reserved.
Prevalence of musculoskeletal injuries among young squash ...
African Journals Online (AJOL)
The aim of the study was to investigate the prevalence of musculoskeletal injuries sustained by young squash players in Malaysia. This study was conducted retrospectively by using. Standardized Nordic Questionnaire (NSQ) during SUKMA 2016 at Kuching, Sarawak, Malaysia. The questionnaires were distributed to the ...
Specific phobia predicts psychopathology in young women
Trumpf, J.; Margraf, J.; Vriends, N.; Meyer, A.H.; Becker, E.S.
2010-01-01
Although specific phobia is characterized by an early age at onset and by high rates of comorbidity, few studies have examined comorbid relationships prospectively. The present study investigated the association between specific phobia and the risk of a broad range of psychopathology among young
Determinants of body fatness in young adults living in a Dutch community
Baecke, J.A.H.
1982-01-01
In 1979, the Department of Human Nutrition of the Agricultural University at Wageningen began a research project on obesity in young adults. The main objectives of this project are the investigation of aetiological aspects and health consequences of obesity. It is a prospective study and is being carried out in a young adult population of three age groups (19-21, 24-26 and 29-31 years as at 1 January 1980) in the Municipality of Ede. The present thesis deals with the investigations into deter...
Military fitness of young South African adults: Does it comply with ...
African Journals Online (AJOL)
The fitness of today's young people is reported to be at a very low level, and this is disconcerting considering that some are needed as military recruits but will not be accepted if they do not pass the military fitness tests. The aims of this study were to investigate the pass rate of young adults (n=41) in the standard South ...
Directory of Open Access Journals (Sweden)
Cosgrave Elizabeth M
2008-09-01
Full Text Available Abstract Background The Mood and Anxiety Symptom Questionnaire (MASQ was designed to specifically measure the Tripartite model of affect and is proposed to offer a delineation between the core components of anxiety and depression. Factor analytic data from adult clinical samples has shown mixed results; however no studies employing confirmatory factor analysis (CFA have supported the predicted structure of distinct Depression, Anxiety and General Distress factors. The Tripartite model has not been validated in a clinical sample of older adolescents and young adults. The aim of the present study was to examine the validity of the Tripartite model using scale-level data from the MASQ and correlational and confirmatory factor analysis techniques. Methods 137 young people (M = 17.78, SD = 2.63 referred to a specialist mental health service for adolescents and young adults completed the MASQ and diagnostic interview. Results All MASQ scales were highly inter-correlated, with the lowest correlation between the depression- and anxiety-specific scales (r = .59. This pattern of correlations was observed for all participants rating for an Axis-I disorder but not for participants without a current disorder (r = .18. Confirmatory factor analyses were conducted to evaluate the model fit of a number of solutions. The predicted Tripartite structure was not supported. A 2-factor model demonstrated superior model fit and parsimony compared to 1- or 3-factor models. These broad factors represented Depression and Anxiety and were highly correlated (r = .88. Conclusion The present data lend support to the notion that the Tripartite model does not adequately explain the relationship between anxiety and depression in all clinical populations. Indeed, in the present study this model was found to be inappropriate for a help-seeking community sample of older adolescents and young adults.
Young and Older Adults' Gender Stereotype in Multitasking.
Strobach, Tilo; Woszidlo, Alesia
2015-01-01
In the present study, we investigated discrepancies between two components of stereotyping by means of the popular notion that women are better at multitasking behaviors: the cognitive structure in individuals (personal belief) and the perceived consensus regarding certain beliefs (perceived belief of groups). With focus on this notion, we examined whether there was empirical evidence for the stereotype's existence and whether and how it was shared among different age groups. Data were collected from 241 young (n = 129) and older (n = 112) German individuals. The reported perceptions of gender effects at multitasking were substantial and thus demonstrated the existence of its stereotype. Importantly, in young and older adults, this stereotype existed in the perception of attributed characteristics by members of a collective (perceived belief of groups). When contrasting this perceived belief of groups and the personal belief, older adults showed a similar level of conformation of the gender stereotype while young adults were able to differentiate between these perspectives. Thus, young adults showed a discrepancy between the stereotype's components cognitive structure in individuals and perceived consensus regarding certain beliefs.
The Relationship of Parenting Styles to Commitment to the Church among Young Adults.
Dudley, Roger L.; Wisbey, Randall L.
2000-01-01
Investigates the effects of parenting style experiences during childhood has on the religious commitment of young adults. Surveyed Seventh-day Adventist young adults (n=653) in United States and Canada. Reveals that the affectionate constraint parenting style produced the largest percentage of members. Includes references. (CMK)
Avoiding shame: young LGBT people, homophobia and self-destructive behaviours.
McDermott, Elizabeth; Roen, Katrina; Scourfield, Jonathan
2008-11-01
This paper reports on findings from qualitative research conducted in the UK that sought to explore the connections between sexual identities and self-destructive behaviours in young people. International evidence demonstrates that there are elevated rates of suicide and alcohol abuse amongst lesbian, gay, bisexual and transgender (LGBT) youth. Rarely included in this body of research are investigations into young LGBT people's views and experiences of self-destructive behaviours. Data from interviews and focus groups with young LGBT participants suggest a strong link between homophobia and self-destructive behaviours. Utilising a discourse analytic approach, we argue that homophobia works to punish at a deep individual level and requires young LGBT people to manage being positioned, because of their sexual desire or gendered ways of being, as abnormal, dirty and disgusting. At the centre of the complex and multiple ways in which young LGBT people negotiate homophobia are 'modalities of shame-avoidance' such as: the routinization and minimizing of homophobia; maintaining individual 'adult' responsibility; and constructing 'proud' identities. The paper argues that these strategies of shame-avoidance suggest young LGBT people manage homophobia individually, without expectation of support and, as such, may make them vulnerable to self-destructive behaviours.
Career drop outs of young elite athletes
Directory of Open Access Journals (Sweden)
Petra Fišer
2007-12-01
Full Text Available The main problem of the study was to examine the characteristics of sports career drop outs of young elite sportswomen and their adaptation to the post-sport life. The sample included 20 ex-young elite sportswomen, who had brought their successful sport careers to an end before the age of 19. We used a modified interview about sports career termination (Cecić Erpič, 1998 for the investigation of the characteristics of their sports careers. To examine the caracteristics of sport careers we used frequency analysis and cluster analysis. The results showed that the participants mostly stated more than one reason for the termination of their career. The most common reasons for career termination were: lack of motivation, bad relations with trainers or co-competitors and dedication to school or education. After the end of a sports career most of the young sportswomen stayed actively in touch with sport, either as trainers, judges, or they remained engaged in sports for recreation.
Fear appeals in HIV-prevention messages: young people's ...
African Journals Online (AJOL)
A total of 10 focus groups were conducted to investigate the role of fear appeals ... Young people were shown a series of images (mostly posters) with ... locally conceived rather than ones developed by large-scale donor-funded campaigns.
Lemoine, Julie; Teal, Stephanie B; Peters, Marissa; Guiahi, Maryam
2017-11-01
This qualitative study explores how adolescents and young women perceive the need for and describe the use of dual method contraception. We interviewed 20 sexually active women aged 16-24 who attended an adolescent-focused Title X family-planning clinic and were using a non-barrier contraceptive method. We used a semi-structured interview guide that included domains related to sexual activity, knowledge of and use of contraceptives and condoms, and relationship factors. We coded transcripts using grounded theory techniques and used an iterative process to develop overarching themes. Dual method contraceptive users primarily discussed pregnancy prevention as their motivating factor. Many expressed anxieties over an unplanned pregnancy and reported condom use as "back-up" contraception. Risk perception for pregnancy or STI acquisition did not necessarily change as relationship trust increased, but rather, their anxiety regarding the negativity of such outcomes decreased. Dual-method contraception use decreased when participants reported that condoms were not readily available, or when they self-described immaturity. Less frequently, participants reported dual method use for sexually transmitted infection (STI) prevention, and many substituted STI testing for condom use. Contraceptive type (short-acting vs. long-acting) did not influence reported attitudes towards dual method use. Health educators and clinicians encourage condom use in young women due to the significant morbidity associated with STI acquisition. Most participants in our study view condoms as a way to improve pregnancy prevention. Acknowledging and addressing this divergence in motivation will allow caregivers to improve strategies for communicating the importance of dual method use. Young women primarily describe pregnancy prevention as the reason for dual method use, STI protection is less salient. Consideration of this viewpoint by health educators and clinicians will allow us to communicate more
Roberts, James A; Pirog, Stephen F
2013-03-01
Background and aims The primary objective of the present research is to investigate the drivers of technological addiction in college students - heavy users of Information and Communication Technology (ICT). The study places cell phone and instant messaging addiction in the broader context of consumption pathologies, investigating the influence of materialism and impulsiveness on these two technologies. Clearly, cell phones serve more than just a utilitarian purpose. Cell phones are used in public and play a vital role in the lives of young adults. The accessibility of new technologies, like cell phones, which have the advantages of portability and an ever increasing array of functions, makes their over-use increasingly likely. Methods College undergraduates (N = 191) from two U.S. universities completed a paper and pencil survey instrument during class. The questionnaire took approximately 15-20 minutes to complete and contained scales that measured materialism, impulsiveness, and mobile phone and instant messaging addiction. Results Factor analysis supported the discriminant validity of Ehrenberg, Juckes, White and Walsh's (2008) Mobile Phone and Instant Messaging Addictive Tendencies Scale. The path model indicates that both materialism and impulsiveness impact the two addictive tendencies, and that materialism's direct impact on these addictions has a noticeably larger effect on cell phone use than instant messaging. Conclusions The present study finds that materialism and impulsiveness drive both a dependence on cell phones and instant messaging. As Griffiths (2012) rightly warns, however, researchers must be aware that one's addiction may not simply be to the cell phone, but to a particular activity or function of the cell phone. The emergence of multi-function smart phones requires that research must dig beneath the technology being used to the activities that draw the user to the particular technology.
Goeggel Simonetti, Barbara; Mono, Marie-Luise; Huynh-Do, Uyen; Michel, Patrik; Odier, Celine; Sztajzel, Roman; Lyrer, Philippe; Engelter, Stefan T; Bonati, Leo; Gensicke, Henrik; Traenka, Christopher; Tettenborn, Barbara; Weder, Bruno; Fischer, Urs; Galimanis, Aekaterini; Jung, Simon; Luedi, Rudolf; De Marchis, Gian Marco; Weck, Anja; Cereda, Carlo W; Baumgartner, Ralf; Bassetti, Claudio L; Mattle, Heinrich P; Nedeltchev, Krassen; Arnold, Marcel
2015-09-01
Ischaemic stroke (IS) in young adults has been increasingly recognized as a serious health condition. Stroke aetiology is different in young adults than in the older population. This study aimed to investigate aetiology and risk factors, and to search for predictors of outcome and recurrence in young IS patients. We conducted a prospective multicentre study of consecutive IS patients aged 16-55 years. Baseline demographic data, risk factors, stroke aetiology including systematic genetic screening for Fabry disease and severity were assessed and related to functional neurological outcome (modified Rankin Scale, mRS), case fatality, employment status, place of residence, and recurrent cerebrovascular events at 3 months. In 624 IS patients (60% men), median age was 46 (IQR 39-51) years and median NIHSS on admission 3 (IQR 1-8). Modifiable vascular risk factors were found in 73%. Stroke aetiology was mostly cardioembolism (32%) and of other defined origin (24%), including cervicocerebral artery dissection (17%). Fabry disease was diagnosed in 2 patients (0.3%). Aetiology remained unknown in 20%. Outcome at 3 months was favourable (mRS 0-1) in 61% and fatal in 2.9%. Stroke severity (p young adults with IS had modifiable vascular risk factors, emphasizing the importance of prevention strategies. Outcome was unfavourable in more than a third of patients and was associated with initial stroke severity and diabetes mellitus. Previous cerebrovascular events predicted recurrent ones.
Regmi, Pramod; Simkhada, Padam; Van Teijlingen, Edwin
2010-01-01
Your article on love and relationship deals with a very important issue (“Love makes the world go round,” Feb. 15, Page 1).It is now widely accepted that romantic relationships and dating are normative among adolescents and young people in Nepal. In our qualitative study of urban and rural young males and females using same sex researchers — in perhaps the first study of dating practice among Nepali youth — almost all of our respondents reported that young people in Nepal form partnerships wi...
How the Project Approach Challenges Young Children
Burns, Marcia V.; Lewis, Alisha L.
2016-01-01
In this article, educators at University Primary School in Champaign, Illinois, share examples and understandings of the ways The Project Approach challenges young children to think critically about topics of importance in their world. Project investigations that provoke academic and social challenges for individuals and classroom communities of…
Selecting patients with young-onset colorectal cancer for mismatch repair gene analysis
DEFF Research Database (Denmark)
Walker, M; O'Sullivan, B; Perakath, B
2007-01-01
BACKGROUND: Young patients with colorectal cancer are at increased risk of carrying a germline mutation in mismatch repair (MMR) genes. This study investigated the role of clinical criteria and immunohistochemistry for MMR proteins in selecting young patients for mutation testing. METHODS: A cohort...... of 56 consecutive patients with colorectal cancer aged less than 45 years were stratified into three groups based on clinical criteria: 'Amsterdam criteria', 'high risk' and 'young onset only'. Immunohistochemistry for four MMR proteins was carried out and the rate of compliance with clinical guidelines...
Emotion awareness and cognitive behavioural therapy in young people with autism spectrum disorder.
Roberts-Collins, Cara; Mahoney-Davies, Gerwyn; Russell, Ailsa; Booth, Anne; Loades, Maria
2017-07-01
Young people with autism spectrum disorder experience high levels of emotional problems, including anxiety and depression. Adapted cognitive behavioural therapy is recommended for such difficulties. However, no evidence suggests whether emotion awareness is important in treatment outcome for young people on the autism spectrum. This study aimed to investigate the potential differences in emotion awareness between (1) young people on the autism spectrum and typically developing youth and (2) young people on the autism spectrum with and without experience of cognitive behavioural therapy. Three groups (aged 11-20 years) participated: (1) typically developing young people ( n = 56); (2) young people on the autism spectrum with no experience of cognitive behavioural therapy ( n = 23); and (3) young people on the autism spectrum who had attended cognitive behavioural therapy ( n = 33). All participants completed the Emotion Awareness Questionnaire-30 item version. Young people on the autism spectrum differed significantly from typically developing young people on the emotional awareness measure. Young people on the autism spectrum who had attended cognitive behavioural therapy scored significantly lower on the Differentiating Emotions subscale, and significantly higher on the Attending to Others' Emotions subscale, compared to young people on the autism spectrum who had not attended cognitive behavioural therapy. This study highlights the importance of psycho-educational components of cognitive behavioural therapy when adapting for young people on the autism spectrum.
Wright, Michelle F; Li, Yan
2013-01-01
This longitudinal study examined normative beliefs about aggression (e.g., face-to-face, cyber) in relation to the engagement in cyber aggression 6 months later among 126 (69 women) young adults. Participants completed electronically administered measures assessing their normative beliefs, face-to-face and cyber aggression at Time 1, and cyber aggression 6 months later (Time 2). We found that men reported more cyber relational and verbal aggression when compared to women. After controlling for each other, Time 1 face-to-face relational aggression was positively related to Time 2 cyber relational aggression, whereas Time 1 face-to-face verbal aggression was positively related to Time 2 cyber verbal aggression. Normative beliefs regarding cyber aggression was positively related to both forms of cyber aggression 6 months later, after controlling for normative beliefs about face-to-face aggression. Furthermore, a significant two-way interaction between Time 1 cyber relational aggression and normative beliefs about cyber relational aggression was found. Follow-up analysis showed that Time 1 cyber relational aggression was more strongly related to Time 2 cyber relational aggression when young adults held higher normative beliefs about cyber relational aggression. A similar two-way interaction was found for cyber verbal aggression such that the association between Time 1 and Time 2 cyber verbal aggression was stronger at higher levels of normative beliefs about cyber verbal aggression. Results are discussed in terms of the social cognitive and behavioral mechanisms associated with the engagement of cyber aggression. © 2013 Wiley Periodicals, Inc.
SELF-ASSESSMENT AMONG YOUNG LEARNERS OF ENGLISH
Directory of Open Access Journals (Sweden)
Arni Sukmiarni
2015-12-01
Full Text Available The implementation of self-assessment among young learners becomes a challenging issue to include in English classroom assessment. The common belief that children cannot self-assess accurately as adults do seems to yield that the inclusion of self-assessment in TEYL is still not prevalent yet. Self-assessment is an assessment involving the ability in assessing one’s own performance in learning. This is strongly related to one’s metacognition development. The tendency of earlier research investigating metacognitive capacities of young children concludes that mecognition in children is a late developing skill (Lai, 2011. In fact, more recent empirical studies conclude that young children have capability of simple metacognition thought (Lai, 2011. Hence, the inclusion of self-assessment in TEYL can be implemented as an assessment supporting other assessment conducted in classroom. Self-assessment is beneficial in improving students’s own awareness of their learning progress. In Indonesian context, English as a foreign language, has been taught in elementary school since 1994 and generally formative and summative assessments as classroom assessments are employed to assess student’s progress in learning. Self-assessment is an assessment that needs to be considered to include in classroom assessment. This paper discusses self-assessment among young learners, in this context elementary school students studying English.
Self-Assessment among Young Learners of English
Directory of Open Access Journals (Sweden)
Arni Sukmiarni
2015-12-01
Full Text Available The implementation of self-assessment among young learners becomes a challenging issue to include in English classroom assessment. The common belief that children cannot self-assess accurately as adults do seems to yield that the inclusion of self-assessment in TEYL is still not prevalent yet. Self-assessment is an assessment involving the ability in assessing one’s own performance in learning. This is strongly related to one’s metacognition development. The tendency of earlier research investigating metacognitive capacities of young children concludes that mecognition in children is a late developing skill (Lai, 2011. In fact, more recent empirical studies conclude that young children have capability of simple metacognition thought (Lai, 2011. Hence, the inclusion of self-assessment in TEYL can be implemented as an assessment supporting other assessment conducted in classroom. Self-assessment is beneficial in improving students’s own awareness of their learning progress. In Indonesian context, English as a foreign language, has been taught in elementary school since 1994 and generally formative and summative assessments as classroom assessments are employed to assess student’s progress in learning. Self-assessment is an assessment that needs to be considered to include in classroom assessment. This paper discusses self-assessment among young learners, in this context elementary school students studying English.
Heart rate and activity profile for young female soccer players
Barbero Álvarez, José Carlos; Gómez López, Maite; Barbero Álvarez, Verónica; Granda Vera, Juan; Castagna, Carlo
2008-01-01
The physical and physiological demands of high-level male soccer have been studied extensively, while few studies have investigated the demands placed on females during match-play, however, there is no information available about the heart rate and activity profile of young female soccer players during match play. Therefore, the aim of this study was to examine cardiovascular (heart-rates HR) and physical demands of young female soccer players during a match. Players were observed during a fr...
Concept Maps: An Alternative Methodology to Assess Young Children
Atiles, Julia T.; Dominique-Maikell, Nikole; McKean, Kathleen
2014-01-01
The authors investigated the utility and efficacy of using concepts maps as a research tool to assess young children. Pre- and post- concept maps have been used as an assessment and evaluation tool with teachers and with older students, typically children who can read and write; this article summarizes an investigation into the utility of using…
Brain structural alterations associated with young women with subthreshold depression.
Li, Haijiang; Wei, Dongtao; Sun, Jiangzhou; Chen, Qunlin; Zhang, Qinglin; Qiu, Jiang
2015-05-18
Neuroanatomical abnormalities in patients with major depression disorder (MDD) have been attracted great research attention. However, the structural alterations associated with subthreshold depression (StD) remain unclear and, therefore, require further investigation. In this study, 42 young women with StD, and 30 matched non-depressed controls (NCs) were identified based on two-time Beck Depression Inventory scores. Whole-brain voxel-based morphometry (VBM) and region of interest method were used to investigate altered gray matter volume (GMV) and white matter volume (WMV) among a non-clinical sample of young women with StD. VBM results indicated that young women with StD showed significantly decreased GMV in the right inferior parietal lobule than NCs; increased GMV in the amygdala, posterior cingulate cortex, and precuneus; and increased WMV in the posterior cingulate cortex and precuneus. Together, structural alterations in specific brain regions, which are known to be involved in the fronto-limbic circuits implicated in depression may precede the occurrence of depressive episodes and influence the development of MDD.
Sex and Relationships Education in Schools: The Views and Experiences of Young People
Selwyn, Neil; Powell, Eryl
2007-01-01
Purpose: The purpose of the paper is to investigate how young people are using school-based sources of sex and relationships education (SRE) to obtain information and advice. Design/methodology/approach: The paper shows how anonymous self-completion questionnaires were administered to young people aged between 12 and 19 years in three secondary…
Sweet and sour preferences in young children and adults: role of repeated exposure
Liem, D.G.; Graaf, de C.
2004-01-01
The authors investigated the influence of repeated exposure to orangeades with added sucrose and different concentrations of citric acid, on the taste preferences of 6- to-11-year-old children and young adults. During an intervention study of 8 days, 59 children (9.2±0.9 years) and 46 young adults
Recruiting Young Adult Cancer Survivors for Behavioral Research
Horowitz, Santina; Marcus, Bess
2012-01-01
Young adults have been dramatically underrepresented in cancer survivorship research. One contributing factor is the difficulty recruiting this population. To identify effective recruitment strategies, the current study assessed the yield of strategies used to recruit young survivors for an exercise intervention including: clinic-based recruitment, recruitment at cancer-related events, mailings, telephone-based recruitment, advertising on the internet, radio, television and social networking media, distributing brochures and word-of-mouth referrals. When taking into account the strategies for which we could track the number of survivors approached, recruitment at an oncology clinic was the most productive: 38 % of those approached were screened and 8 % enrolled. When evaluating which strategy yielded the greatest percentage of the sample, however, mailings were the most productive. Given widespread use of the internet and social networking by young adults, investigators should also consider these low-cost recruitment strategies. PMID:22810954
Recruiting young adult cancer survivors for behavioral research.
Rabin, Carolyn; Horowitz, Santina; Marcus, Bess
2013-03-01
Young adults have been dramatically underrepresented in cancer survivorship research. One contributing factor is the difficulty recruiting this population. To identify effective recruitment strategies, the current study assessed the yield of strategies used to recruit young survivors for an exercise intervention including: clinic-based recruitment, recruitment at cancer-related events, mailings, telephone-based recruitment, advertising on the internet, radio, television and social networking media, distributing brochures and word-of-mouth referrals. When taking into account the strategies for which we could track the number of survivors approached, recruitment at an oncology clinic was the most productive: 38 % of those approached were screened and 8 % enrolled. When evaluating which strategy yielded the greatest percentage of the sample, however, mailings were the most productive. Given widespread use of the internet and social networking by young adults, investigators should also consider these low-cost recruitment strategies.
Moyo, S.; Isaacs, F.; Gelderbloem, S.; Verver, S.; Hawkridge, A. J.; Hatherill, M.; Tameris, M.; Geldenhuys, H.; Workman, L.; Pai, M.; Hussey, G.; Hanekom, W. A.; Mahomed, H.
2011-01-01
Although the literature on interferon-gamma release assays on tuberculosis (TB) in children has increased, data pertaining to young children remain relatively limited. To compare results from the tuberculin skin test (TST) and the QuantiFERON®-TB Gold In-Tube assay (QFT) in children aged <3 years
Noor eesti teater ja Noor-Eesti. Young Estonian Theatre and Young Estonia
Directory of Open Access Journals (Sweden)
Katri Aaslav-Tepandi
2012-04-01
Full Text Available This article begins by examining points of intersection between two professional theatres, ”Estonia” and ”Vanemuine” (both established in 1906, their young directors – Karl Menning, Paul Pinna, Theodor Altermann, and Karl Jungholz, and the literary movement Young Estonia. Subsequently, we will consider Young Estonia’s theatrical ideals and the influence of these ideas on later Estonian theatrical life. Since not much information has survived regarding direct personal contacts between ”movers and shakers” in the theatre world and Young Estonians, the main focus here shall be on indirect creative connections and influences. One such context is education: like the Young Estonians, theatre activists of the younger generation aspired to place themselves on the larger map of European culture. Thus, their artistic beliefs and goals shall be examined in relation to those of Young Estonians’ quest for modern culture. Pinna, Altermann, Menning, Jungholz, and others went on study tours to Germany and France, where they were energized and inspired by innovative German and Russian theatres, by naturalistic staging, and by psychological realism, both in acting and in performance style. Among their models were A. Antoine’s Théâtre- Libre in Paris, K. Stanislavski’s Art Theatre in Moscow, O. Brahm’s Lessing-Theater, and M. Reinhardt’s Deutsches Theater in Berlin. These models were likewise known to the Young Estonians, but if theatre activists oriented themselves more fundamentally to German naturalist and realist dramatic art, Young Estonians were more taken with ”theatrical theatre” with its symbolist and impressionist influences. The Young Estonians attended performances at both theatres, ”Vanemuine” and ”Estonia”, and wrote numerous theatre reviews. Yet in the Young Estonia albums (yearbooks and in the magazine Young Estonia, theatre topics have a relatively modest representation. Young Estonians did not have direct
Jaffre, A; Guidolin, B; Ruidavets, J-B; Nasr, N; Larrue, V
2017-05-01
Up to 50% of ischaemic strokes in young adults are classified as cryptogenic despite extensive work-up. We sought to evaluate the prevalence of non-obstructive carotid atherosclerosis (NOCA) and its association with patent foramen ovale (PFO) in young adults with cryptogenic stroke (CS). Patients aged 18-54 years, consecutively treated for first-ever CS in an academic stroke service, were included. NOCA was assessed using carotid ultrasound examination and was defined as carotid plaque with young adults with CS. NOCA is negatively associated with PFO. Detecting NOCA is an important component of stroke investigation in young adults. © 2017 EAN.
Young and older adults’ gender stereotype in multitasking
Directory of Open Access Journals (Sweden)
Tilo eStrobach
2015-12-01
Full Text Available In the present study, we investigated discrepancies between two components of stereotyping by means of the popular notion that women are better at multitasking behaviors: the cognitive structure in individuals (personal belief and the perceived consensus regarding certain beliefs (perceived belief of groups. With focus on this notion, we examined whether there was empirical evidence for the stereotype’s existence and whether and how it was shared among different age groups. Data were collected from 241 young (n = 129 and older (n = 112 German individuals. The reported perceptions of gender effects at multitasking were substantial and thus demonstrated the existence of its stereotype. Importantly, in young and older adults, this stereotype existed in the perception of attributed characteristics by members of a collective (perceived belief of groups. When contrasting this perceived belief of groups and the personal belief, older adults showed a similar level of conformation of the gender stereotype while young adults were able to differentiate between these perspectives. Thus, young adults showed a discrepancy between the stereotype’s components cognitive structure in individuals and perceived consensus regarding certain beliefs.
"Hedge Your Bets": Technology's Role in Young Gay Men's Relationship Challenges.
McKie, Raymond M; Milhausen, Robin R; Lachowsky, Nathan J
2017-01-01
Technology is playing an increasingly pervasive role among young gay men in the process of meeting potential romantic or sexual partners. We investigated challenges posed by technology related to young gay men's relationships. Focus groups (n = 9) of young gay men aged 18-24 (n = 43) were transcribed verbatim, and thematic analysis was used to identify two major themes regarding challenges to relationship development and maintenance. Subthemes include unrealistic expectations of relationships, inauthentic self-presentation online, sexual primacy over romance, increased opportunities for infidelity, and jealousy. The implications of this study for sexual education and sexual health promotion are discussed.
Ryninks, Kirsty; Sutton, Eileen; Thomas, Elizabeth; Jago, Russell; Shield, Julian P H; Burren, Christine P
2015-01-01
To investigate young people's attitudes to, and understanding of, physical activity on glycaemic control in Type 1 Diabetes Mellitus. Four focus groups with 11-14 and 15-16 year olds were conducted with twelve young people with Type 1 Diabetes, from within a larger study investigating physical activity and fitness. Qualitative analysis of the focus group data was performed using Interpretative Phenomenological Analysis. Four superordinate themes were identified: Benefits of Exercise, Knowledge and Understanding, Information and Training and "You can do anything". Young people felt that exercising helped them to manage their diabetes and had a beneficial psychological and physical impact on their bodies. They reported a lack of knowledge and understanding about diabetes among school staff and other young people. The overwhelming sense from young people was that although diabetes impacts upon their lives, with preparation, physical activity can take place as normal. Whilst young people had an awareness of the physical and psychological benefits of exercise in managing their diabetes, they experienced difficulties at school. Professional support and discussions with young people, giving tailored strategies for managing Type 1 Diabetes during exercise are needed. Healthcare teams should ensure that the support and educational needs of school staff are met. Providing more opportunities to empower young people to take on the responsibility for their Type 1 Diabetes care is merited. Young people felt diabetes did not stop them from participating in activities; it is simply a part of them that needs managing throughout life.
ECNS '99 - Young scientists forum
DEFF Research Database (Denmark)
Ceretti, M.; Janssen, S.; McMorrow, D.F.
2000-01-01
The Young Scientists Forum is a new venture for ECNS and follows the established tradition of an active participation by young scientists in these conferences. At ECNS '99 the Young Scientists Forum brought together 30 young scientists from 13 European countries. In four working groups, they disc......The Young Scientists Forum is a new venture for ECNS and follows the established tradition of an active participation by young scientists in these conferences. At ECNS '99 the Young Scientists Forum brought together 30 young scientists from 13 European countries. In four working groups......, they discussed emerging scientific trends in their areas of expertise and the instrumentation required to meet the scientific challenges. The outcome was presented in the Young Scientists Panel on the final day of ECNS '99. This paper is a summary of the four working group reports prepared by the Group Conveners...
Monks, Helen; Cardoso, Patricia; Papageorgiou, Alana; Carolan, Catherine; Costello, Leesa; Thomas, Laura
2015-01-01
Social media is a central component in the lives of many young people, and provides innovative potential to conduct research among this population. Ethical issues around online research have been subject to much debate, yet young people have seldom been consulted to provide a youth perspective and voice. Eight (8) focus groups involving 48 Grade 9 Western Australian secondary school students aged 13-14 years were held in 2012, to investigate how young people perceive the feasibility and accep...
DEFF Research Database (Denmark)
Simpson, Deane
Young-Old examines contemporary architectural and urban mutations that have emerged as a consequence of one of the key demographic transformations of our time: aging populations. Distinguishing between different phases of old age, the book identifies the group known as the “young old” as a remark...
Young module multiplicities and classifying the indecomposable Young permutation modules
Gill, Christopher C.
2012-01-01
We study the multiplicities of Young modules as direct summands of permutation modules on cosets of Young subgroups. Such multiplicities have become known as the p-Kostka numbers. We classify the indecomposable Young permutation modules, and, applying the Brauer construction for p-permutation modules, we give some new reductions for p-Kostka numbers. In particular we prove that p-Kostka numbers are preserved under multiplying partitions by p, and strengthen a known reduction given by Henke, c...
Disciplining young children: the role of verbal instructions and reasoning.
Blum, N J; Williams, G E; Friman, P C; Christophersen, E R
1995-08-01
Pediatricians are often asked to advise parents who are having difficulty managing the oppositional behaviors of their toddlers and preschool-age children. A large number of articles provide advice to pediatricians and parents on effective disciplinary strategies. However, despite the fact that verbal explanations, reasoning, and instructions are commonly used by parents, few articles directly address the use of these strategies to affect children's behavior. In this paper, we review studies that explicitly investigate the ability of adults' verbal explanations or instructions to alter the behavior of young children. These studies suggest that under most circumstances, verbal explanations and instructions are not effective in changing young children's problem behaviors. We then discuss how theories in developmental and behavioral psychology help explain the limitations of using verbal reasoning and instructions to change young children's problem behaviors. Finally, we provide some recommendations for parents on the use of verbal explanations and instructions in disciplining young children.
WORKING WITH YOUNG PEOPLE: A MODEL OF SOCIAL INTERVENTION
Directory of Open Access Journals (Sweden)
Dovilė Lisauskienė
2016-09-01
Full Text Available Social workers, working with young people ought to be aware of the values, needs and problems of contemporary young people. Therefore, it is necessary to develop study programmes of Social Work that would reflect the current situation of modern youth and be oriented towards effective techniques for working with young people. The most common methods described in the literature are counseling, supervision, case management, self-reflection. The article highlights the method of social intervention, which objectively and fully assesses the problem situation and establishes the connections and relationships between the young man and his relatives, friends or authorities. This method helps to enable young people to solve their own problems. The aim of the research is to analyze the application features of the social intervention model when working with young people. The objectives are to discuss the activities of youth organizations in the field of social 99SOCIALINIO TINKLO INTERVENCIJOS MODELIO TAIKYMAS DIRBANT SU JAUNIMU work; to highlight the methods of social workers‘ practice; to investigate the application of social intervention model, enabling young people to solve their own problems. The methods applied include comparative analysis of scientific literature, monitoring, social intervention model. The survey revealed that when social workers enable young people to solve their own problems, a model of social intervention allows to evaluate not only the relationships of close people or family members, but also highlights the roles of youth organizations or social workers and their positive effect on the customer‘s actions. Thus, when applying the method of social intervention, social workers play an important role, as well as their professional knowledge and skills to establish the connection with the client are extremely important in order to promote the client‘s reflection.
An application of the driver behavior questionnaire to Chinese carless young drivers.
Zhang, Qian; Jiang, Zuhua; Zheng, Dongpeng; Wang, Yifan; Man, Dong
2013-01-01
Carless young drivers refers to those drivers aged between 18 and 25 years who have a driver's license but seldom have opportunities to practice their driving skills because they do not have their own cars. Due to China's lower private car ownership, many young drivers turn into carless young drivers after licensure, and the safety issue associated with them has become a matter of great concern in China. Because few studies have examined the driving behaviors of these drivers, this study aims to utilize the Driver Behavior Questionnaire (DBQ) to investigate the self-reported driving behaviors of Chinese carless young drivers. A total of 523 Chinese carless young drivers (214 females, 309 males) with an average age of 21.91 years completed a questionnaire including the 27-item DBQ and demographics. The data were first randomized into 2 subsamples for factor analysis and then combined together for the following analyses. Both an exploratory factor analysis (EFA, n = 174) and a confirmatory factor analysis (CFA, n = 349) were performed to investigate the factor structure of the DBQ. Correlation analysis was conducted to examine the relationships between the demographics and the DBQ scales' variables. Multivariate linear regression and logistic regression were performed to investigate the prediction of the DBQ scales and crash involvement in the previous year. The EFA produced a 4-factor structure identified as errors, violations, attention lapses, and memory lapses, and the CFA revealed a good model fit after the removal of one item with a low factor loading and the permission of the error covariance between some items. The Chinese carless young drivers reported a comparatively low level of aberrant driving behaviors. The 3 most frequently reported behaviors were all lapses and the 3 least were all violations. Gender was the only significant predictor of the 2 lapses scales and lifetime mileage was the only significant predictor of the violations scale. Only the
Cells derived from young bone marrow alleviate renal aging.
Yang, Hai-Chun; Rossini, Michele; Ma, Li-Jun; Zuo, Yiqin; Ma, Ji; Fogo, Agnes B
2011-11-01
Bone marrow-derived stem cells may modulate renal injury, but the effects may depend on the age of the stem cells. Here we investigated whether bone marrow from young mice attenuates renal aging in old mice. We radiated female 12-mo-old 129SvJ mice and reconstituted them with bone marrow cells (BMC) from either 8-wk-old (young-to-old) or 12-mo-old (old-to-old) male mice. Transfer of young BMC resulted in markedly decreased deposition of collagen IV in the mesangium and less β-galactosidase staining, an indicator of cell senescence. These changes paralleled reduced expression of plasminogen activator inhibitor-1 (PAI-1), PDGF-B (PDGF-B), the transdifferentiation marker fibroblast-specific protein-1 (FSP-1), and senescence-associated p16 and p21. Tubulointerstitial and glomerular cells derived from the transplanted BMC did not show β-galactosidase activity, but after 6 mo, there were more FSP-1-expressing bone marrow-derived cells in old-to-old mice compared with young-to-old mice. Young-to-old mice also exhibited higher expression of the anti-aging gene Klotho and less phosphorylation of IGF-1 receptor β. Taken together, these data suggest that young bone marrow-derived cells can alleviate renal aging in old mice. Direct parenchymal reconstitution by stem cells, paracrine effects from adjacent cells, and circulating anti-aging molecules may mediate the aging of the kidney.
Effect of the Young modulus variability on the mechanical behaviour of a nuclear containment vessel
Energy Technology Data Exchange (ETDEWEB)
Larrard, T. de, E-mail: delarrard@lmt.ens-cachan.f [LMT-ENS Cachan, CNRS/UPMC/PRES UniverSud Paris (France); Colliat, J.B.; Benboudjema, F. [LMT-ENS Cachan, CNRS/UPMC/PRES UniverSud Paris (France); Torrenti, J.M. [Universite Paris-Est, LCPC (France); Nahas, G. [IRSN/DSR/SAMS/BAGS, Fontenay-aux-Roses (France)
2010-12-15
This study aims at investigating the influence of the Young modulus variability on the mechanical behaviour of a nuclear containment vessel in case of a loss of cooling agent accident and under the assumption of an elastic behaviour. To achieve this investigation, the Monte-Carlo Method is carried out thanks to a middleware which encapsulates the different components (random field generation, FE simulations) and enables calculations parallelisation. The main goal is to quantify the uncertainty propagation by comparing the maximal values of outputs of interest (orthoradial stress and Mazars equivalent strain) for each realisation of the considered random field with the ones obtained from a reference calculation taking into account uniform field (equal to the expected value of the random field). The Young modulus is supposed to be accurately represented by a weakly homogeneous random field and realisations are provided through its truncated Karhunen-Loeve expansion. This study reveals that the expected value for the maximal equivalent strain in the structure is more important when considering the Young modulus spatial variability than the value obtained from a deterministic approach with a uniform Young modulus field. The influence of the correlation length is investigated too. Finally it is shown that there is no correlation between the maximal values location of equivalent strain and the ones where the Young modulus extreme values are observed for each realisation.
... Healthy Aging Nutrition for Young Men Print Email Nutrition for Young Men Reviewed by Taylor Wolfram, MS, ... 2017 XiXinXing/iStock/Thinkstock For many young men, nutrition isn't always a focus. There are many ...
Young people's food practices and social relationships. A thematic synthesis.
Neely, Eva; Walton, Mat; Stephens, Christine
2014-11-01
Food practices are embedded in everyday life and social relationships. In youth nutrition promotion little attention is awarded to this centrality of food practices, yet it may play a pivotal role for young people's overall health and wellbeing beyond the calories food provides. Limited research is available explicitly investigating how food practices affect social relationships. The aim of this synthesis was therefore to find out how young people use everyday food practices to build, strengthen, and negotiate their social relationships. Using a thematic synthesis approach, we analysed 26 qualitative studies exploring young people's food practices. Eight themes provided insight into the ways food practices affected social relationships: caring, talking, sharing, integrating, trusting, reciprocating, negotiating, and belonging. The results showed that young people use food actively to foster connections, show their agency, and manage relationships. This synthesis provides insight into the settings of significance for young people where more research could explore the use of food in everyday life as important for their social relationships. A focus on social relationships could broaden the scope of nutrition interventions to promote health in physical and psychosocial dimensions. Areas for future research are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.
Face age modulates gaze following in young adults.
Ciardo, Francesca; Marino, Barbara F M; Actis-Grosso, Rossana; Rossetti, Angela; Ricciardelli, Paola
2014-04-22
Gaze-following behaviour is considered crucial for social interactions which are influenced by social similarity. We investigated whether the degree of similarity, as indicated by the perceived age of another person, can modulate gaze following. Participants of three different age-groups (18-25; 35-45; over 65) performed an eye movement (a saccade) towards an instructed target while ignoring the gaze-shift of distracters of different age-ranges (6-10; 18-25; 35-45; over 70). The results show that gaze following was modulated by the distracter face age only for young adults. Particularly, the over 70 year-old distracters exerted the least interference effect. The distracters of a similar age-range as the young adults (18-25; 35-45) had the most effect, indicating a blurred own-age bias (OAB) only for the young age group. These findings suggest that face age can modulate gaze following, but this modulation could be due to factors other than just OAB (e.g., familiarity).
Young generation actions in Finland
International Nuclear Information System (INIS)
Tanskanen, A.
2000-01-01
The Finnish Young Generation was established in 1998 as a working group of the Finnish Nuclear Society to tackle the declining of the nuclear expertise. The objectives of the Young Generation are to attract more young students to the nuclear field, motivate and train young employees, enhance the transfer of knowledge between the generations, and to enable the young students and employees in nuclear field to build a personal network of contacts. This paper summarizes the results of the Finnish Young Generation program. (orig.)
DEFF Research Database (Denmark)
Roelsgaard Obling, Anne
2015-01-01
Book review of: Kevin Roose: "Young Money: Inside the Hidden World of Wall Street's Post-Crash Recruits". New York: Grand Central Publishing, 2014. 320 pp.......Book review of: Kevin Roose: "Young Money: Inside the Hidden World of Wall Street's Post-Crash Recruits". New York: Grand Central Publishing, 2014. 320 pp....
Özbek, E.; Bongers, I.L.; Lobbestael, J.; van Nieuwenhuizen, Ch.
2015-01-01
This study investigated the relationship between acculturation and psychological problems in Turkish and Moroccan young adults living in the Netherlands. A sample of 131 healthy young adults aged between 18 and 24 years old, with a Turkish or Moroccan background was recruited using snowball
de Jong, Eveline P.; van den Beuken, Monique G. A.; van Elzakker, Erika P. M.; Wolthers, Katja C.; Sprij, Arwen J.; Lopriore, Enrico; Walther, Frans J.; Brus, Frank
2018-01-01
Background: Sepsis-like illness is a main cause for hospital admission in young infants. Our aim was to investigate incidence, epidemiology and clinical characteristics of enterovirus (EV) and human parechovirus (HPeV) infections in young infants with sepsis-like illness. Methods: This is a
Domestic cat allergen and allergic sensitisation in young children
Chen, Chih-Mei; Gehring, Ulrike; Wickman, Magnus; Hoek, Gerard; Giovannangelo, Mariella; Nordling, Emma; Wijga, Alet; de Jongste, Johan; Pershagen, Goeran; Almqvist, Catarina; Kerkhof, Marjan; Bellander, Tom; Wichmann, H. -Erich; Brunekreef, Bert; Heinrich, Joachim
Studies have presented conflicting associations between cat allergen exposure and sensitisation and atopic disease. We therefore investigated the association between the observed domestic cat allergen level and cat sensitisation in young children in four study populations from three European
Bioanalysis of eukaryotic organelles
Czech Academy of Sciences Publication Activity Database
Satori, Ch. P.; Henderson, M. M.; Krautkramer, E. A.; Košťál, Vratislav; Distefano, M. M.; Arriaga, E. A.
2013-01-01
Roč. 113, č. 4 (2013), s. 2733-2811 ISSN 0009-2665 R&D Projects: GA ČR(CZ) GBP206/12/G014 Grant - others:GA AV ČR(CZ) M200311201 Institutional support: RVO:68081715 Keywords : green fluorescent protein * atomic-force microscopy * capillary electrophoretic analysis Subject RIV: CB - Analytical Chemistry , Separation Impact factor: 45.661, year: 2013
Bioanalysis of eukaryotic organelles
Czech Academy of Sciences Publication Activity Database
Satori, Ch. P.; Henderson, M. M.; Krautkramer, E. A.; Košťál, Vratislav; Distefano, M. M.; Arriaga, E. A.
2013-01-01
Roč. 113, č. 4 (2013), s. 2733-2811 ISSN 0009-2665 R&D Projects: GA ČR(CZ) GBP206/12/G014 Grant - others:GA AV ČR(CZ) M200311201 Institutional support: RVO:68081715 Keywords : green fluorescent protein * atomic-force microscopy * capillary electrophoretic analysis Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 45.661, year: 2013
Bioanalysis in microfluidic devices.
Khandurina, Julia; Guttman, András
2002-01-18
Microfabricated bioanalytical devices (also referred to as laboratory-on-a-chip or micro-TAS) offer highly efficient platforms for simultaneous analysis of a large number of biologically important molecules, possessing great potential for genome, proteome and metabolome studies. Development and implementation of microfluidic-based bioanalytical tools involves both established and evolving technologies, including microlithography, micromachining, micro-electromechanical systems technology and nanotechnology. This article provides an overview of the latest developments in the key device subject areas and the basic interdisciplinary technologies. Important aspects of DNA and protein analysis, interfacing issues and system integration are all thoroughly discussed, along with applications for this novel "synergized" technology in high-throughput separations of biologically important molecules. This review also gives a better understanding of how to utilize these technologies as well as to provide appropriate technical solutions to problems perceived as being more fundamental.
Pezzini, Alessandro; Grassi, Mario; Lodigiani, Corrado; Patella, Rosalba; Gandolfo, Carlo; Casoni, Federica; Musolino, Rossella; Calabrò, Rocco Salvatore; Bovi, Paolo; Adami, Alessandro; Delodovici, Maria Luisa; Del Zotto, Elisabetta; Rota, Lidia Luciana; Rasura, Maurizia; Del Sette, Massimo; Giossi, Alessia; Volonghi, Irene; Zini, Andrea; Cerrato, Paolo; Costa, Paolo; Magoni, Mauro; Iacoviello, Licia; Padovani, Alessandro
2011-01-01
the mechanisms underlying the relationship between migraine and ischemic stroke remain uncertain. The aim of the present study was to investigate the predictive value of major cardiovascular risk factors, cardiac interatrial abnormalities, and additional biological markers on migraine subtypes in young adults with ischemic stroke. ischemic stroke patients aged 45 years or younger were consecutively enrolled as part of the Italian Project on Stroke in Young Adults. A comprehensive evaluation was performed including assessment of self-reported migraine and cardiovascular risk factors, interatrial right-to-left shunt, and genotyping to detect factor V Leiden and the G20210A mutation in the prothrombin gene. nine hundred eighty-one patients (mean age, 36.0 ± 7.6 years; 50.7% women) were included. The risk of migraine with aura increased with decreasing number of cardiovascular risk factors (OR, 0.50; 95% CI, 0.24-0.99 for 2 factors or more), increasing number of thrombophilic variants (OR, 2.21; 95% CI, 1.05-4.68 for carriers of at least 1 of the 2), and the presence of right-to-left shunt (OR, 2.41; 95% CI, 1.37-3.45), as compared to patients without migraine. None of these factors had influence on the risk of migraine without aura. in young adults with ischemic stroke, low cardiovascular risk profile, right-to-left shunt, and an underlying procoagulant state are predictors of migraine with aura. The biological effects of these factors should be considered in future studies aimed at investigating the mechanisms linking migraine to brain ischemia.
Directory of Open Access Journals (Sweden)
Kirsty Ryninks
Full Text Available To investigate young people's attitudes to, and understanding of, physical activity on glycaemic control in Type 1 Diabetes Mellitus.Four focus groups with 11-14 and 15-16 year olds were conducted with twelve young people with Type 1 Diabetes, from within a larger study investigating physical activity and fitness. Qualitative analysis of the focus group data was performed using Interpretative Phenomenological Analysis.Four superordinate themes were identified: Benefits of Exercise, Knowledge and Understanding, Information and Training and "You can do anything". Young people felt that exercising helped them to manage their diabetes and had a beneficial psychological and physical impact on their bodies. They reported a lack of knowledge and understanding about diabetes among school staff and other young people. The overwhelming sense from young people was that although diabetes impacts upon their lives, with preparation, physical activity can take place as normal.Whilst young people had an awareness of the physical and psychological benefits of exercise in managing their diabetes, they experienced difficulties at school. Professional support and discussions with young people, giving tailored strategies for managing Type 1 Diabetes during exercise are needed. Healthcare teams should ensure that the support and educational needs of school staff are met. Providing more opportunities to empower young people to take on the responsibility for their Type 1 Diabetes care is merited. Young people felt diabetes did not stop them from participating in activities; it is simply a part of them that needs managing throughout life.
Ryninks, Kirsty; Sutton, Eileen; Thomas, Elizabeth; Jago, Russell; Shield, Julian P. H.; Burren, Christine P.
2015-01-01
Aims To investigate young people’s attitudes to, and understanding of, physical activity on glycaemic control in Type 1 Diabetes Mellitus. Methods Four focus groups with 11–14 and 15–16 year olds were conducted with twelve young people with Type 1 Diabetes, from within a larger study investigating physical activity and fitness. Qualitative analysis of the focus group data was performed using Interpretative Phenomenological Analysis. Results Four superordinate themes were identified: Benefits of Exercise, Knowledge and Understanding, Information and Training and “You can do anything”. Young people felt that exercising helped them to manage their diabetes and had a beneficial psychological and physical impact on their bodies. They reported a lack of knowledge and understanding about diabetes among school staff and other young people. The overwhelming sense from young people was that although diabetes impacts upon their lives, with preparation, physical activity can take place as normal. Conclusions Whilst young people had an awareness of the physical and psychological benefits of exercise in managing their diabetes, they experienced difficulties at school. Professional support and discussions with young people, giving tailored strategies for managing Type 1 Diabetes during exercise are needed. Healthcare teams should ensure that the support and educational needs of school staff are met. Providing more opportunities to empower young people to take on the responsibility for their Type 1 Diabetes care is merited. Young people felt diabetes did not stop them from participating in activities; it is simply a part of them that needs managing throughout life. PMID:26465770
Directory of Open Access Journals (Sweden)
Moisés de Hoyo Lora
2008-07-01
Full Text Available http://dx.doi.org/10.5007/1980-0037.2008v10n3p255 The anthropometric characteristics of athletes can determine their sporting performance. For this reason, we’ve defined the somatotype of young volleyball players in order to be able to control their sports training and to ensure their appropriate athletic development. In the present investigation 154 male and female volleyball players (aged from 12 to 14 years were analyzed. Data were collected according to the ISAK protocol. The results show an endomesomorphic profile for male and female volleyball players agreeing with the predominant profile at these ages. However, after comparing these data with results obtained in other studies, we observed a certain homogeneity in the male somatotype, invalidating the current trend of using this parameter as criteria to select young sports talent. However, somatotype could be a factor to take into account with female athletes, since their profile is much more heterogeneous.
Peer Influence on IPV by Young Adult Males: Investigating the Case for a Social Norms Approach.
McKool, Marissa; Stephenson, Rob; Winskell, Kate; Teten Tharp, Andra; Parrott, Dominic
2017-08-01
Nearly 32% of women report experiencing physical violence from an intimate partner and more than 8% report being raped by a significant other in their lifetime. Young people's perceptions that their peers perpetrate relationship violence have been shown to increase the odds of self-reported perpetration. Yet, limited research has been conducted on this relationship as individuals begin to age out of adolescence. The present study sought to examine the link between the perception of peer perpetration of intimate partner violence (IPV) and self-reported IPV perpetration among a sample of predominately young adult (21-35 years) males. This study also explored the discordance between the perception of peer IPV behavior and self-reported perpetration. Data from 101 male peer dyads ( n = 202) were taken from a study on the effects of alcohol and bystander intervention in Atlanta, Georgia. Thirty-six percent ( n = 73) of men reported perpetrating physical IPV and 67% ( n = 135) reported perpetrating sexual IPV in the past 12 months. Nearly 35% ( n = 55) of the sample reported that none of their peers had perpetrated physical IPV, which contradicted their friend's self-report of physical IPV perpetration. Similarly, 68% ( n = 115) of the men perceived none of their peers to have perpetrated sexual IPV, which contradicted their friend's self-report of sexual IPV perpetration. Discordance variables were significantly associated with self-reported perpetration for both physical (χ 2 = 152.7, p peer IPV perpetration among young adult males. Findings suggest a traditional social norms approach to IPV prevention, which seeks to persuade individuals that negative behaviors are less common than perceived, may not be the best approach given a significant number of men believed their friends were nonviolent when they had perpetrated violence.
Adegoke, Alfred A.
Noting the lack of self-concept research in nonwestern cultures and the need to determine if a western measure of self-image is embedded in the same network of constructs in another culture, this study examined the appropriateness of using the Self Image Questionnaire for Young Adolescents (SIQYA) with Nigerian students. Participating in the study…
Clinical evaluation of myocardial involvement in acute myopericarditis in young adults.
Saricam, Ersin; Saglam, Yasemin; Hazirolan, Tuncay
2017-05-22
Myocardial involvement in young adults has various causes. Acute myopericarditis is one of the myocardial involvements in young adults. It is easy to confuse with acute ST-elevation myocardial infarction because of the electrocardiographic features. This study aims to investigate a number of imaging techniques and clinical features for acute myopericarditis in young adults (defined as myocardial brightness in the left ventricle regions, especially in posterior and lateral wall. Focal echobright was observed in the 75 of 77 cases of acute myopericarditis in transthoracic echocardiogram. This sign was confirmed by cardiac magnetic resonance imaging. Focal echobright sensitivity was 95%; its specificity was 93%; its predictive was 95.2%. Pericardial effusion (83%) was observed in group I behind posterior wall. Its specificity was 81%; its sensitivity was 65%; predictivity was 73%. Pericardial effusion and myocardial focal echobright in echocardiography can be quite sensitive indicators for acute myopericarditis in young adults.
Calsbeek, H.; Rijken, M.; Bekkers, M.J.T.M.; Berge Henegouwen, G.P. van; Dekker, J.
2006-01-01
Coping strategies were compared across adolescents and young adults with several chronic digestive disorders and healthy peers, and across age groups. Subsequently, the impact of coping on performance in school and leisure activities was investigated. Participants were adolescents and young adults
Povinelli, Daniel J.; And Others
1996-01-01
Investigated the ability of young children to recognize themselves in delayed videotapes and recent photographs. Results suggested a significant developmental delay in young children's success on mark tests of self-recognition using delayed feedback as compared to live feedback, which may have important implications for characterizing the…
AN INVESTIGATION OF THE DINIG-OUT BEHAVIOR OF ROMANIAN YOUNG PEOPLE
Directory of Open Access Journals (Sweden)
BĂL TESCU CODRUŢA ADINA
2013-12-01
Full Text Available Food services are basic services of the tourism offer. Unlike the other elements of the tourism product sold to a visitor, the offer of food units target to a high extent the residents. The habit to satisfy the need of food & beverage in specialized units, concept known under the name of “dining-out”, records in Romania a lower spread in comparison with developed states. This situation is determined by the low level of incomes, the lack of the lunch break with a duration of at least one hour in the working program of many companies which could favor serving the meal in a food unit, etc, but also the concern of the restaurants to satisfy the demand for events (weddings, baptisms, etc or satisfying the needs of socialization and amusement of population during evenings. The article aims to highlight the opinions and attitudes of young consumers from Romania regarding the food service consumption, the elements which determine the decision to eat in a restaurant and the issues that might favor this action.
Handgrip force steadiness in young and older adults
DEFF Research Database (Denmark)
Blomkvist, Andreas W; Eika, Fredrik; de Bruin, Eling D
2018-01-01
) was investigated in a test-retest design with seven days between sessions. Ten young and thirty older adults were recruited and handgrip steadiness was tested at 5%, 10% and 25% of maximum voluntary contraction (MVC) using Nintendo Wii Balance Board (WBB). Coefficients of variation were calculated from the mean...
Psychosocial and Health Behavior Outcomes of Young Adults with Asthma or Diabetes.
Berge, Jerica M; Bauer, Katherine W; Eisenberg, Marla E; Denny, Kara; Neumark-Sztainer, Dianne
2012-04-30
Previous research has shown a relationship between childhood/adolescent chronic conditions and negative health behaviors, psychological outcomes, and social outcomes. Less is known about whether these negative outcomes are experienced by young adults with chronic health conditions. The purpose of this paper is to investigate how young adults' BMI, health behaviors, and psychological and social outcomes differ depending on whether they have diabetes, asthma, or neither of these chronic conditions. Data were drawn from the third wave of Project EAT-III: Eating and Activity in Young Adults, a population-based study of 2287 young adults (mean age = 25.3; range 19.8 - 31.2). General linear models were used to test differences in BMI, health behaviors (e.g., fast food intake) and psychosocial outcomes (e.g. depressive symptoms) by young adults' chronic disease status. Young adults with diabetes had higher BMIs, engaged in less physical activity and more unhealthy weight control behaviors and binge eating, had lower self-esteem and lower body satisfaction, and experienced more depressive symptoms and appearance-based teasing compared to young adults with asthma or no chronic conditions, after adjusting for age, race/ethnicity, socio-economic status (SES) and, when relevant, for BMI. There were no significant differences between young adults with asthma and young adults with no chronic condition on all of the psychosocial and health behavior outcomes. Young adults with diabetes reported higher prevalence of negative health behaviors and psychosocial outcomes. Providers may find it useful to assess for negative health behaviors and psychosocial variables with young adults with diabetes in order to improve treatment and quality of life for these individuals.
The Role of Personality Traits in Young Adult Fruit and Vegetable Consumption
Conner, Tamlin S.; Thompson, Laura M.; Knight, Rachel L.; Flett, Jayde A. M.; Richardson, Aimee C.; Brookie, Kate L.
2017-01-01
This project investigated how individual differences in the big-five personality traits (neuroticism, extraversion, openness to experience, conscientiousness, and agreeableness) predicted plant-food consumption in young adults. A total of 1073 participants from two samples of young adults aged 17–25 reported their daily servings of fruits, vegetables, and two unhealthy foods for comparison purposes using an Internet daily diary for 21 or 13 days (micro-longitudinal, correlational design). Par...
Directory of Open Access Journals (Sweden)
Helen Monks
2015-04-01
Full Text Available Social media is a central component in the lives of many young people, and provides innovative potential to conduct research among this population. Ethical issues around online research have been subject to much debate, yet young people have seldom been consulted to provide a youth perspective and voice. Eight (8 focus groups involving 48 Grade 9 Western Australian secondary school students aged 13-14 years were held in 2012, to investigate how young people perceive the feasibility and acceptability of social media when used as a research tool to investigate various issues relevant to their mental health and wellbeing. Whilst young people recognise many benefits of researchers using social media in this way, such as its relevance, innovation and accessibility, there were salient issues of privacy, consent, and practicality that require careful negotiation. There is a need for continued exploration and scientific debate of the moral and ethical implications of using social media for research, to help ensure this is employed in an appropriate and effective way that is respectful of and sensitive to the needs and views of young people.
Zeng, Wei; Fisher, Alison L; Musson, Donald G; Wang, Amy Qiu
2004-07-05
A novel method was developed and assessed to extend the lifetime of extraction columns of high-throughput liquid chromatography (HTLC) for bioanalysis of human plasma samples. In this method, a 15% acetic acid solution and 90% THF were respectively used as mobile phases to clean up the proteins in human plasma samples and residual lipids from the extraction and analytical columns. The 15% acetic acid solution weakens the interactions between proteins and the stationary phase of the extraction column and increases the protein solubility in the mobile phase. The 90% THF mobile phase prevents the accumulation of lipids and thus reduces the potential damage on the columns. Using this novel method, the extraction column lifetime has been extended to about 2000 direct plasma injections, and this is the first time that high concentration acetic acid and THF are used in HTLC for on-line cleanup and extraction column lifetime extension.
Masculine ideology, norms, and HIV prevention among young Black men
Hall, Naomi M.; Applewhite, Sheldon
2014-01-01
This study examines the relationship between masculine ideology, adherence to norms, and HIV prevention among young Black heterosexual and gay men on the campus of a historically Black college/university. The data from four focus groups and nine individual interviews (N = 35) were aggregated and two recurring themes emerged: sexual communication, and mate availability. Additional themes related to HIV prevention were stigma, protection, and testing. The importance of investigating masculinity with young men is highlighted and implications for professionals working with college students to prevent the transmission of HIV are included. PMID:25525415
Masculine ideology, norms, and HIV prevention among young Black men.
Hall, Naomi M; Applewhite, Sheldon
2013-01-01
This study examines the relationship between masculine ideology, adherence to norms, and HIV prevention among young Black heterosexual and gay men on the campus of a historically Black college/university. The data from four focus groups and nine individual interviews (N = 35) were aggregated and two recurring themes emerged: sexual communication, and mate availability. Additional themes related to HIV prevention were stigma, protection, and testing. The importance of investigating masculinity with young men is highlighted and implications for professionals working with college students to prevent the transmission of HIV are included.
Anxiety and Related Disorders and Concealment in Sexual Minority Young Adults.
Cohen, Jeffrey M; Blasey, Christine; Barr Taylor, C; Weiss, Brandon J; Newman, Michelle G
2016-01-01
Sexual minorities face greater exposure to discrimination and rejection than heterosexuals. Given these threats, sexual minorities may engage in sexual orientation concealment in order to avoid danger. This social stigma and minority stress places sexual minorities at risk for anxiety and related disorders. Given that three fourths of anxiety disorder onset occurs before the age of 24, the current study investigated the symptoms of generalized anxiety disorder, social phobia, panic disorder, posttraumatic stress disorder, and depression in sexual minority young adults relative to their heterosexual peers. Secondarily, the study investigated sexual orientation concealment as a predictor of anxiety and related disorders. A sample of 157 sexual minority and 157 heterosexual young adults matched on age and gender completed self-report measures of the aforementioned disorders, and indicated their level of sexual orientation concealment. Results revealed that sexual minority young adults reported greater symptoms relative to heterosexuals across all outcome measures. There were no interactions between sexual minority status and gender, however, women had higher symptoms across all disorders. Sexual minority young women appeared to be at the most risk for clinical levels of anxiety and related disorders. In addition, concealment of sexual orientation significantly predicted symptoms of social phobia. Implications are offered for the cognitive and behavioral treatment of anxiety and related disorders in this population. Copyright © 2015. Published by Elsevier Ltd.
A confidence in itself, as mortgage of successful competition activity of the young chess-players
Directory of Open Access Journals (Sweden)
Khoroshavina A.V.
2012-04-01
Full Text Available Presents the results of the study the basic aspects of self-confidence of young players. The study involved 54 young chess players. Of these, 34 students Kherson CYSS Chess. 20 players from different regions of Ukraine. Age investigated from 10 to 15 years. The dependence of the confidence of participation in competitions for young players on the level of anxiety, motivational set, strong-willed self-control. In the result of performance of young chess players in the competition is directly proportional to the strength of motivation to succeed installation. Most athletes have been observed high levels of self-willed. Self-control depends on the experience of participation of young players in the competition, as well as facilities manager.
The health of young Swedish Sami with special reference to mental health
Directory of Open Access Journals (Sweden)
Lotta Omma
2012-07-01
Full Text Available Objectives. To investigate the health of young Sami in Sweden and the relationship between health and experience of negative societal treatment due to ethnicity, as well as socio-demographic background factors. Study design. Cross-sectional population-based questionnaire study. Methods. A total of 876 persons aged 18–28 and involved in Sami associated activities were addressed, and 516 (59% responded to a questionnaire investigating physical health, mental health, and stress. Data were analyzed with regard to gender, family situation, occupation, education, enculturation factors and experience of being badly treated because of ethnicity. Results. A majority of the young Sami reported feeling healthy, but close to half of the group reported often having worries, often forgetting things and often experiencing lack of time for doing needed things. Women and those living alone reported a more negative health. Furthermore, half of the group had perceived bad treatment because of Sami ethnicity, and this was negatively associated with some aspects of mental health. Conclusion. The young Sami had a rather good and possibly slightly better health than other young Swedes, except regarding worries and stress. A high degree of bad treatment due to Sami ethnicity and its negative association with health, may partly explain the high degree of some health problems.
Liver protein expression in young pigs in response to a high-fat diet and diet restriction
DEFF Research Database (Denmark)
Sejersen, Henrik; Sørensen, Martin Tang; Larsen, Torben
2013-01-01
We investigated the liver response in young pigs to a high-fat diet (containing 25% animal fat) and diet restriction (equivalent to 60% of maintenance) using differential proteome analysis. The objective was to investigate whether young pigs can be used to model the liver response in adolescents...... to a high-fat diet and diet restriction-induced BW loss. The high-fat diet increased (P high-fat diet had normal glucose tolerance and liver lipid content despite a general increase (P ...-density lipoprotein decreased (P high-fat diet in young pigs is similar to that of humans in terms of increased fatty acid oxidation whereas the liver response to diet restriction is similar to humans...
What Works for Disconnected Young People: A Scan of the Evidence. MDRC Working Paper
Treskon, Louisa
2016-01-01
The purpose of this paper was to conduct a scan of the current state of the evidence regarding what works in helping disconnected young people, defined as the population of young people ages 16 to 24 who are not connected to work or school. The following four main research questions were investigated: (1) What local, state, and federal policies…
Spanish Young Generation (JJNN) Activities
International Nuclear Information System (INIS)
Millan, Miguel
2008-01-01
Spanish Young Generation has been very active during 2006-2008. JJNN have mainly focused on communication activities, as conferences at universities, schools and nuclear companies. Lately, becoming in referent of the young politics, journalist and the young people in Nuclear Subjects is the new and most challenging target of the Spanish Young Generation. In order to accomplish with their objects and commitments with their members, JJNN are developing all kinds of activities focused in the young people and the JJNN members. (authors)
Spanish Young Generation (JJNN) Activities
Energy Technology Data Exchange (ETDEWEB)
Millan, Miguel [INITEC Nuclear- Westinghouse, Padilla 17, 28006 Madrid (Spain)
2008-07-01
Spanish Young Generation has been very active during 2006-2008. JJNN have mainly focused on communication activities, as conferences at universities, schools and nuclear companies. Lately, becoming in referent of the young politics, journalist and the young people in Nuclear Subjects is the new and most challenging target of the Spanish Young Generation. In order to accomplish with their objects and commitments with their members, JJNN are developing all kinds of activities focused in the young people and the JJNN members. (authors)
Directory of Open Access Journals (Sweden)
Kimberley C. O'Sullivan
2017-12-01
Conclusion: The integrated results confirm that cold housing and risk of fuel poverty are important problems for young people in New Zealand. Results contribute to the evidence-base for policy targeting of schemes such as the Government-sponsored retrofitting of insulation to households with dependent children.
Young adults’ use of food as a self-therapeutic intervention
Directory of Open Access Journals (Sweden)
Elisabeth Von Essen
2014-04-01
Full Text Available The aim of this study was to investigate how young adults use their lived body as a starting point for lifestyle explorations and as a strategy for well-being. The transcripts of 10 interviews with persons 18 to 33 years old, collected in Sweden, were analysed for variation in the practises and experiences related to this way of using food. An application of the descriptive phenomenological psychological research method guided the process. The young adults were: (1 listening to the body; (2 moderating conditions and feelings; (3 developing vitality and resilience; (4 creating mindful space for rest, and (5 participating in creative activity. The results show how young adults perceive their choice of food and related practises associated with positive feelings and experiences as ways to promote well-being and mitigate different problems in life. The usefulness of knowledge about how young adults try to use food for self-therapy by enhancing mind-body awareness is discussed in relation to health issues and food-related interventions.
Father Involvement, Nurturant Fathering, and the Psychological Well-Being of Young Adult Daughters
Peterson, Camille C.
2007-01-01
The present study was conducted to investigate the relationship between father involvement, nurturant fathering, and the psychological well-being among young adult women. A total of 99 young adult, female, university students completed retrospective measures of nurturant fathering, father involvement, and measures of current psychological well-being (measured in terms of self-esteem, life satisfaction, and psychological distress). Results indicated that retrospective perceptions of both fat...
Tablet-Based eBooks for Young Children: What Does the Research Say?
Reich, SM; Yau, JC; Warschauer, M
2016-01-01
Young children's use of electronic books (eBooks) is increasing as handheld touch screen devices, such as tablets, become increasingly available. Although older children's reading on tablets has been more broadly investigated, less is known about the impacts of digital reading for infant, toddlers, and preschoolers. This review compares the educational affordances of reading on tablets versus print books for young children's learning.A qualitative synthesis of research on tablet-based eReadin...
Anorexia as a Psychoemotional Pathology of Young Women of the 21 Century
Alena, A.; Ekaterina, A.
2015-01-01
BACKGROUND Anorexia nervosa characterized by deliberate weight loss, induced and sustained by the patient. It occurs most commonly in adolescent girls and young women, but adolescent boys and young men may also be affected. The investigation of anorexia is caused by increase of the number of people with this pathology within the last decade, difficulties of its diagnostics and treatment as well as long-lasting and complicated rehabilitation and possible relapsing course. METHODS The intervent...
Lehmann, Meshan; Hilimire, Matthew R; Yang, Lawrence H; Link, Bruce G; DeVylder, Jordan E
2016-07-01
Self-esteem is a major contributor to risk for repeated suicide attempts. Prior research has shown that awareness of stigma is associated with reduced self-esteem among people with mental illness. No prior studies have examined the association between self-esteem and stereotype awareness among individuals with past suicide attempts. To understand the relationship between stereotype awareness and self-esteem among young adults who have and have not attempted suicide. Computerized surveys were administered to college students (N = 637). Linear regression analyses were used to test associations between self-esteem and stereotype awareness, attempt history, and their interaction. There was a significant stereotype awareness by attempt interaction (β = -.74, p = .006) in the regression analysis. The interaction was explained by a stronger negative association between stereotype awareness and self-esteem among individuals with past suicide attempts (β = -.50, p = .013) compared with those without attempts (β = -.09, p = .037). Stigma is associated with lower self-esteem within this high-functioning sample of young adults with histories of suicide attempts. Alleviating the impact of stigma at the individual (clinical) or community (public health) levels may improve self-esteem among this high-risk population, which could potentially influence subsequent suicide risk.
Effect of behavior training on learning and memory of young rats with fetal growth restriction
Institute of Scientific and Technical Information of China (English)
Li Xuelan; Gou Wenli; Huang Pu; Li Chunfang; Sun Yunping
2008-01-01
Objective: To investigate the effect of behavior training on the learning and memory of young rats with fetal growth restriction (FGR). Methods: The model of FGR was established by passive smoking method to pregnant rats.The new-born rats were divided into FGR group and normal group, and then randomly subdivided into trained and untrained group respectively. Morris water maze behavior training was performed on postnatal months 2 and 4, then learning and memory abilities of young rats were measured by dark-avoidance testing and step-down testing. Results: In the dark-avoidance and step-down testing, the young rats' performance of FGR group was worse than that of control group, and the trained group was better than the untrained group significantly. Conclusion: FGR young rats have descended learning and memory abilities. Behavior training could improve the young rats' learning and memory abilities, especially for the FGR young rats.
Depressed mood as a risk factor for unprotected sex in young people.
Brown, Adrienne; Yung, Alison; Cosgrave, Elizabeth; Killackey, Eóin; Buckby, Joe; Stanford, Carrie; Godfrey, Katherine; McGorry, Patrick
2006-09-01
Young people may place themselves and others at risk of sexually transmitted infections (STI) and/or the human immunodeficiency virus (HIV) through engaging in unprotected sex. Mental health problems may play an important role in sex-related risk behaviour. The current research was an investigation of depressed mood and condom use in a help-seeking sample of young people in Melbourne, Australia. The sample comprised 76 sexually active young people aged 15-24 years who were referred to ORYGEN Youth Health, a public mental health service in Melbourne, Australia. Controlling for demographic characteristics and substance use, multivariate logistic regression examined depressed mood as a predictor of condom use at last sexual intercourse. Half of the sample reported condom use the last time they had sexual intercourse. Depressed mood, female gender and unemployment increased the likelihood that participants engaged in unprotected sex. A high proportion of young people, particularly those who are depressed, are failing to protect themselves from STI/HIV. Mental health services working with young people have the opportunity to implement initiatives aimed at reducing risk of STI/HIV infection.
Elevated Autism Spectrum Disorder Traits in Young Children with OCD.
Stewart, Elyse; Cancilliere, Mary Kathryn; Freeman, Jennifer; Wellen, Brianna; Garcia, Abbe; Sapyta, Jeffrey; Franklin, Martin
2016-12-01
Studies have shown a high prevalence of autistic spectrum traits in both children and adults with psychiatric disorders; however the prevalence rate has not yet been investigated in young children with OCD. The aim of the current study was to (1) determine whether ASD traits indicated by the Social Communication Questionnaire (SCQ) and the Social Responsiveness Scale (SRS) were elevated in young children with OCD who do not have a specific ASD diagnosis and (2) determine if ASD traits were associated with OCD severity. Participants (N = 127) were children ages 5-8 years enrolled in the pediatric obsessive-compulsive disorder treatment study for young children (POTS Jr.). Results indicated that the SRS showed elevated autistic traits in the sample and was associated with OCD severity whereas the SCQ did not indicate heightened ASD symptoms. Implications of these results are discussed.
Body piercings and posttraumatic stress disorder symptoms in young adults.
Bui, Eric; Rodgers, Rachel; Simon, Naomi M; Jehel, Louis; Metcalf, Christina A; Birmes, Philippe; Schmitt, Laurent
2013-02-01
Body piercing, which is prevalent in young adults, has been suggested to be associated with features usually related to posttraumatic stress disorder (PTSD) such as high-risk behaviours and psychopathological symptoms and might be motivated by a wish to deal with prior traumatic experiences. However, to date, no research has investigated the relationship between this practice and PTSD symptoms. The present research aims to investigate the possible relationship between body piercing and PTSD symptoms in French-speaking young adults. According to our results, having two or more body piercings was associated with a twofold increased risk for scoring above the cut-off score for PTSD on the PTSD checklist. Our findings suggest that two or more body piercings might serve as an identifiable marker for PTSD symptoms and may have important implications for clinical screening. Copyright © 2012 John Wiley & Sons, Ltd.
Colour Vision Impairment in Young Alcohol Consumers.
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Alódia Brasil
Full Text Available Alcohol consumption among young adults is widely accepted in modern society and may be the starting point for abusive use of alcohol at later stages of life. Chronic alcohol exposure can lead to visual function impairment. In the present study, we investigated the spatial luminance contrast sensitivity, colour arrangement ability, and colour discrimination thresholds on young adults that weekly consume alcoholic beverages without clinical concerns. Twenty-four young adults were evaluated by an ophthalmologist and performed three psychophysical tests to evaluate their vision functions. We estimated the spatial luminance contrast sensitivity function at 11 spatial frequencies ranging from 0.1 to 30 cycles/degree. No difference in contrast sensitivity was observed comparing alcohol consumers and control subjects. For the evaluation of colour vision, we used the Farnsworth-Munsell 100 hue test (FM 100 test to test subject's ability to perform a colour arrangement task and the Mollon-Reffin test (MR test to measure subject's colour discrimination thresholds. Alcohol consumers made more mistakes than controls in the FM100 test, and their mistakes were diffusely distributed in the FM colour space without any colour axis preference. Alcohol consumers also performed worse than controls in the MR test and had higher colour discrimination thresholds compared to controls around three different reference points of a perceptually homogeneous colour space, the CIE 1976 chromaticity diagram. There was no colour axis preference in the threshold elevation observed among alcoholic subjects. Young adult weekly alcohol consumers showed subclinical colour vision losses with preservation of spatial luminance contrast sensitivity. Adolescence and young adult age are periods of important neurological development and alcohol exposure during this period of life might be responsible for deficits in visual functions, especially colour vision that is very sensitive to
Young skateboarders their everyday
Directory of Open Access Journals (Sweden)
Marcelo Rampazzo
2016-09-01
Full Text Available In this research, we focus on young people and their daily lives, bringing elements discussing leisure, family, education and work. Research conducted with a group of young skaters in a public track skating in the city of Porto Alegre - RS. In a total nine months of direct observation, each reported in Field Diaries. We seek to understand how the leisure of young people who gave the practice of skateboarding, was related to other aspects of their daily lives. After completing the work, we consider that - to remain in practice the skateboard - young people needed to reconcile the charges of their families, in addition to labels and stereotypes imposed from "outside" the universe of practitioners of this sport. We noticed also that young people go through all this in order to keep their "projects" on the skateboard.
The limit shape problem for ensembles of Young diagrams
Hora, Akihito
2016-01-01
This book treats ensembles of Young diagrams originating from group-theoretical contexts and investigates what statistical properties are observed there in a large-scale limit. The focus is mainly on analyzing the interesting phenomenon that specific curves appear in the appropriate scaling limit for the profiles of Young diagrams. This problem is regarded as an important origin of recent vital studies on harmonic analysis of huge symmetry structures. As mathematics, an asymptotic theory of representations is developed of the symmetric groups of degree n as n goes to infinity. The framework of rigorous limit theorems (especially the law of large numbers) in probability theory is employed as well as combinatorial analysis of group characters of symmetric groups and applications of Voiculescu's free probability. The central destination here is a clear description of the asymptotic behavior of rescaled profiles of Young diagrams in the Plancherel ensemble from both static and dynamic points of view.
Nutrition Status of Young Elite Female German Football Players.
Braun, Hans; von Andrian-Werburg, Judith; Schänzer, Wilhelm; Thevis, Mario
2018-02-01
To investigate energy intake, energy expenditure, and the nutritional status of young female elite football players using 7-day food and activity records and blood parameters. A total of 56 female elite football players [14.8 (0.7) y] completed the requested food and activity protocols. Misreporting was assessed by the ratio of energy intake to energy expenditure. The food records were analyzed concerning energy and macronutrient and micronutrient intakes, and energy expenditure was calculated using predictive equations. Hematological data and 25-hydroxyvitamin D serum concentrations were determined. Mean energy intake was 2262 (368) kcal/d [40.5 (7.0) kcal/kg/d] and estimated EE averaged 2403 (195) kcal/d. Fifty-three percent of the players exhibited an energy availability nutrition status of some young female football players. As a consequence, strategies have to be developed for a better information and application of sport nutrition practice among young female football players.
Whole Body Vibration Improves Cognition in Healthy Young Adults
Regterschot, G. Ruben H.; Van Heuvelen, Marieke J. G.; Zeinstra, Edzard B.; Fuermaier, Anselm B.M.; Tucha, Lara; Koerts, Janneke; Tucha, Oliver; Van der Zee, Eddy A.
2014-01-01
This study investigated the acute effects of passive whole body vibration (WBV) on executive functions in healthy young adults. Participants (112 females, 21 males; age: 20.5 +/- 2.2 years) underwent six passive WBV sessions (frequency 30 Hz, amplitude approximately 0.5 mm) and six non-vibration
Smartphone use and smartphone addiction among young people in Switzerland
Haug, Severin; Castro, Raquel Paz; Kwon, Min; Filler, Andreas; Kowatsch, Tobias; Schaub, Michael P.
2015-01-01
Background and Aims Smartphone addiction, its association with smartphone use, and its predictors have not yet been studied in a European sample. This study investigated indicators of smartphone use, smartphone addiction, and their associations with demographic and health behaviour-related variables in young people. Methods A convenience sample of 1,519 students from 127 Swiss vocational school classes participated in a survey assessing demographic and health-related characteristics as well as indicators of smartphone use and addiction. Smartphone addiction was assessed using a short version of the Smartphone Addiction Scale for Adolescents (SAS-SV). Logistic regression analyses were conducted to investigate demographic and health-related predictors of smartphone addiction. Results Smartphone addiction occurred in 256 (16.9%) of the 1,519 students. Longer duration of smartphone use on a typical day, a shorter time period until first smartphone use in the morning, and reporting that social networking was the most personally relevant smartphone function were associated with smartphone addiction. Smartphone addiction was more prevalent in younger adolescents (15–16 years) compared with young adults (19 years and older), students with both parents born outside Switzerland, persons reporting lower physical activity, and those reporting higher stress. Alcohol and tobacco consumption were unrelated to smartphone addiction. Discussion Different indicators of smartphone use are associated with smartphone addiction and subgroups of young people have a higher prevalence of smartphone addiction. Conclusions The study provides the first insights into smartphone use, smartphone addiction, and predictors of smartphone addiction in young people from a European country, which should be extended in further studies. PMID:26690625
Smartphone use and smartphone addiction among young people in Switzerland.
Haug, Severin; Castro, Raquel Paz; Kwon, Min; Filler, Andreas; Kowatsch, Tobias; Schaub, Michael P
2015-12-01
Smartphone addiction, its association with smartphone use, and its predictors have not yet been studied in a European sample. This study investigated indicators of smartphone use, smartphone addiction, and their associations with demographic and health behaviour-related variables in young people. A convenience sample of 1,519 students from 127 Swiss vocational school classes participated in a survey assessing demographic and health-related characteristics as well as indicators of smartphone use and addiction. Smartphone addiction was assessed using a short version of the Smartphone Addiction Scale for Adolescents (SAS-SV). Logistic regression analyses were conducted to investigate demographic and health-related predictors of smartphone addiction. Smartphone addiction occurred in 256 (16.9%) of the 1,519 students. Longer duration of smartphone use on a typical day, a shorter time period until first smartphone use in the morning, and reporting that social networking was the most personally relevant smartphone function were associated with smartphone addiction. Smartphone addiction was more prevalent in younger adolescents (15-16 years) compared with young adults (19 years and older), students with both parents born outside Switzerland, persons reporting lower physical activity, and those reporting higher stress. Alcohol and tobacco consumption were unrelated to smartphone addiction. Different indicators of smartphone use are associated with smartphone addiction and subgroups of young people have a higher prevalence of smartphone addiction. The study provides the first insights into smartphone use, smartphone addiction, and predictors of smartphone addiction in young people from a European country, which should be extended in further studies.
Young Migrants and Discourses on Young Migrants in the Netherlands
Gerritsen, Debby; Maier, Robert
2012-01-01
This article compares the perspectives of young migrants in the Netherlands with the dominant discourse on "migrants" at present. The integration of young "migrants" have been studied in the European research projects TRESEGY and PROFACITY with the help of a number of ethnographic studies and a questionnaire in the Netherlands.…
Heck, Nicholas C.; Lindquist, Lauri M.; Machek, Greg R.; Cochran, Bryan N.
2014-01-01
This study investigates the mediating role of school victimization in the relationship between lesbian, gay, bisexual, and transgender (LGBT) young adults' feelings of high school belonging and current mental health (both depression and general psychological distress) outcomes. A total of 145 LGBT young adults were recruited from college LGBT…
McVeigh, Francis
2014-01-01
Purpose - This research project has investigated the "Company Programme" of the charity YE and how effective it is at increasing Life Skills in young people. Data has been obtained using student questionnaires and teacher interviews. Previous studies have been completed on "Life Skills" and "Enterprise Programmes",…
Nirogi, Ramakrishna; Padala, Naga Surya Prakash; Boggavarapu, Rajesh Kumar; Kalaikadhiban, Ilayaraja; Ajjala, Devender Reddy; Bhyrapuneni, Gopinadh; Muddana, Nageswara Rao
2016-06-01
Skin is the target site to evaluate the pharmacokinetic parameters of topical applications. Sample preparation is one of the influential steps in the bioanalysis of drugs in the skin. Evaluation of dermatopharmacokinetics at preclinical stage is challenging due to lack of proper sample preparation method. There is a need for an efficient sample preparation procedure for quantification of drugs in the skin using LC-MS/MS. The skin samples treated with collagenase followed by homogenization using a bead beater represents a best-fit method resulting in uniform homogenate for reproducible results. A new approach involving enzymatic treatment and mechanical homogenization techniques were evaluated for efficient sample preparation of skin samples in the bioanalysis.
Directory of Open Access Journals (Sweden)
Marcos Cohen
2017-01-01
Full Text Available This research investigates if company social-environmental responsibility (SER is an attraction and retention factor for young professionals in two studies. The first study, an experiment, investigates whether such practices influence the attraction exerted by the company as a prospect employer among undergraduate students, considering different wage and professional development conditions. The second study, a survey, investigates the impact of company SER on voluntary turnover among trainees, controlling for individual differences and satisfaction with income, growth and interests. The results suggest that SER is an important element in the attractiveness exercised by companies as they recruit young professionals, and in the retention of trainees, since it is statistically associated with the likelihood of them leaving their companies after disputed selection processes and expensive training programs.
‘Interrupted Interviews’: listening to young people with autism in transition to college
Directory of Open Access Journals (Sweden)
Jacqui Shepherd
2015-03-01
Full Text Available This article examines the methodological approaches used in a research project that investigated the lived experiences of young people with autism as they made the transition from special schools to mainstream colleges of Further Education. A combination of visual methods using iPad applications and walking interviews were explored in an attempt to develop ways of engaging young people with autism in research and to privilege their voice in their own transition. The strengths and challenges of these methods are examined here and illustrated through the experience and responses of one young person in the study and his engagement with the research.
Azab, Walid; Damiani, Armando Mario; Ochs, Andreas; Osterrieder, Nikolaus
2018-02-01
Elephant endotheliotropic herpesviruses (EEHVs) are a continuous threat for young Asian elephants. We report a laboratory-confirmed infection of a 5-year-old female Asian elephant (AZ_2016) in the Berlin Zoologischer Garten. Initially, high EEHV-1 loads were detected in trunk swabs obtained from the young elephant during routine screening. The animal showed no clinical signs except for slight irritability. EEHV-1 was continuously shed for almost one year, with fluctuations in viral load from time to time. Our investigations highlight the continuous threat of EEHV-1 to young captive Asian elephants and stress the importance of routine monitoring of captive elephants to allow early detection of infection.
Experimental Young's modulus calculations
International Nuclear Information System (INIS)
Chen, Y.; Jayakumar, R.; Yu, K.
1994-01-01
Coil is a very important magnet component. The turn location and the coil size impact both mechanical and magnetic behavior of the magnet. The Young's modulus plays a significant role in determining the coil location and size. Therefore, Young's modulus study is essential in predicting both the analytical and practical magnet behavior. To determine the coil Young's modulus, an experiment has been conducted to measure azimuthal sizes of a half quadrant QSE101 inner coil under different loading. All measurements are made at four different positions along an 8-inch long inner coil. Each measurement is repeated three times to determine the reproducibility of the experiment. To ensure the reliability of this experiment, the same measurement is performed twice with a open-quotes dummy coil,close quotes which is made of G10 and has the same dimension and similar azimuthal Young's modulus as the inner coil. The difference between the G10 azimuthal Young's modulus calculated from the experiments and its known value from the manufacturer will be compared. Much effort has been extended in analyzing the experimental data to obtain a more reliable Young's modulus. Analysis methods include the error analysis method and the least square method
Energy Technology Data Exchange (ETDEWEB)
Riedel, Adric R. [Department of Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Alam, Munazza K.; Rice, Emily L.; Cruz, Kelle L. [Department of Astrophysics, The American Museum of Natural History, New York, NY 10024 (United States); Henry, Todd J., E-mail: arr@caltech.edu [RECONS Institute, Chambersburg, PA (United States)
2017-05-10
We present a spectroscopic and kinematic analysis of 79 nearby M dwarfs in 77 systems. All of these dwarfs are low-proper-motion southern hemisphere objects and were identified in a nearby star survey with a demonstrated sensitivity to young stars. Using low-resolution optical spectroscopy from the Red Side Spectrograph on the South African Large Telescope, we have determined radial velocities, H-alpha, lithium 6708 Å, and potassium 7699 Å equivalent widths linked to age and activity, and spectral types for all of our targets. Combined with astrometric information from literature sources, we identify 44 young stars. Eighteen are previously known members of moving groups within 100 pc of the Sun. Twelve are new members, including one member of the TW Hydra moving group, one member of the 32 Orionis moving group, 9 members of Tucana-Horologium, one member of Argus, and two new members of AB Doradus. We also find 14 young star systems that are not members of any known groups. The remaining 33 star systems do not appear to be young. This appears to be evidence of a new population of nearby young stars not related to the known nearby young moving groups.
Young Scientists Need Emotional Support and a Framework When Drafting Scientific Articles
Directory of Open Access Journals (Sweden)
Jannie Laursen
2017-01-01
Full Text Available Introduction. When teaching young scientists to write scientific articles, it is important to consider several aspects of learning including intrinsic motivation, since the scientific work can be demanding in a different way than routine clinical work. The aim of this study was to investigate young scientists’ experience of the process of writing research articles with focus on motivating factors and the feeling of success, in order to improve the process. Methods. This was a qualitative study using focus groups to explore young scientists’ feelings and motivations regarding the process of writing scientific articles. Participants were young scientists including young medical doctors and medical students spending dedicated time on research. Content analysis was used to analyze the focus group interviews. Results. Sixteen informants participated in the study in three groups. Two major themes were identified: emotional support and setting and framework. Emotional support covered three subthemes: support from peers and supervisors, appearances, and motivation. The setting and framework theme covered four subthemes: deadlines, retreats, consciousness, and expectations. Conclusion. We found emotional support, frame-setting, and the avoidance of failures to be important factors for the feeling of success when young scientists are in the process of learning how to write scientific articles.
[Vulvovaginitis in young girls].
Olejek, Anita; Kellas-Sleczka, Sylwia; Kozak-Darmas, Iwona; Bilska, Anna; Zamłyński, Jacek; Horak, Stanisław; Nowak, Leszek
2009-12-01
Vulvovaginitis is the most common cause of gynecological complaints in young girls. Factors which cause vulvovaginitis include, among other things, low level of sexual hormones (hypoestrogenism), the anatomical proximity of the rectum and delicate vulvar skin and vaginal mucosa. Usually vulvovaginitis in young girls is caused by non-specific factors. The aim of the study was to present the most frequent causes of vulvovaginitis in young girls.
Electronic games of movement: it is sport or simulation in the perception of young people?
Directory of Open Access Journals (Sweden)
Ana Paula Salles da Silva
2017-09-01
Full Text Available Electronic games have been one of the main ways of access of young to technology in Brazil, leading to new experiences in social practices.The objective of this study is to identify the perception of young people on the experience of electronic games of movement with sports theme. Methodology: 24 young elementary school students were investigated, divided into 3 groups. Each group participated in 10 sessions with electronic games of movement of 3 hours each. During the sessions the speeches of the young people were recorded in a field diary. Results: departing from the speeches of young people the experiment with electronic games of movement emerges as a mediated and unique experience. It is mediated because it interposes itself between subject and object and it is unique because the way is the experience itself.Conclusions: the perception of the young people indicates a conceptual enlargement in which the comprehension of sports is expanded by the experiences with technology.
Reading to young children : A head-start in life?
Kalb, G.; van Ours, J.C.
This paper investigates the importance of parents reading to their young children. Using Australian data we find that parental reading to children at age 4–5 has positive and significant effects on reading skills and cognitive skills (including numeracy skills) of these children at least up to age
Friends Drinking Together: Young Adults' Evolving Support Practices
Dresler, Emma; Anderson, Margaret
2018-01-01
Purpose: Young adult's drinking is about pleasure, a communal practice of socialising together in a friendship group. The purpose of this paper is to investigate the evolving support practices of drinking groups for better targeting of health communications messages. Design/methodology/approach: This qualitative descriptive study examined the…
The Development of Human Capital in Young Entrepreneurs
Hickie, James
2011-01-01
This paper provides insights into the human capital development of a group of young entrepreneurs, all of whom have built growth businesses with turnovers of between 1M British Pounds and 90M British Pounds. Their development of knowledge and skills was investigated before and during the creation of their first main ventures. This is significant…
Analýza a charakterizace biomolekul a biočástic kapilárními elektromigračními metodami
Czech Academy of Sciences Publication Activity Database
Tůmová, Tereza; Kašička, Václav
2016-01-01
Roč. 26, č. 2 (2016), s. 25-28 ISSN 1210-1737 Institutional support: RVO:61388963 Keywords : capillary electrophoresis * bioanalysis * biomolecules Subject RIV: CB - Analytical Chemistry, Separation
Do online mental health services improve help-seeking for young people? A systematic review.
Kauer, Sylvia Deidre; Mangan, Cheryl; Sanci, Lena
2014-03-04
Young people regularly use online services to seek help and look for information about mental health problems. Yet little is known about the effects that online services have on mental health and whether these services facilitate help-seeking in young people. This systematic review investigates the effectiveness of online services in facilitating mental health help-seeking in young people. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, literature searches were conducted in PubMed, PsycINFO, and the Cochrane library. Out of 608 publications identified, 18 studies fulfilled the inclusion criteria of investigating online mental health services and help-seeking in young people aged 14-25 years. Two qualitative, 12 cross-sectional, one quasi-experimental, and three randomized controlled trials (RCTs) were reviewed. There was no change in help-seeking behavior found in the RCTs, while the quasi-experimental study found a slight but significant increase in help-seeking. The cross-sectional studies reported that online services facilitated seeking help from a professional source for an average of 35% of users. The majority of the studies included small sample sizes and a high proportion of young women. Help-seeking was often a secondary outcome, with only 22% (4/18) of studies using adequate measures of help-seeking. The majority of studies identified in this review were of low quality and likely to be biased. Across all studies, young people regularly used and were generally satisfied with online mental health resources. Facilitators and barriers to help-seeking were also identified. Few studies examine the effects of online services on mental health help-seeking. Further research is needed to determine whether online mental health services effectively facilitate help-seeking for young people.
Piper, Alan T
2015-10-01
Much of the work within economics attempting to understand the relationship between age and well-being has focused on the U-shape, whether it exists and, more recently, potential reasons for its existence. This paper focuses on one part of the lifecycle rather than the whole: young people. This focus offers a better understanding of the age-well-being relationship for young people, and helps with increasing general understanding regarding the U-shape itself. The empirical estimations employ both static and dynamic panel estimations, with the latter preferred for several reasons. The empirical results are in line with the U-shape, and the results from the dynamic analysis indicate that this result is a lifecycle effect. Copyright © 2015 Elsevier Ltd. All rights reserved.
An investigation on facial and cranial anthropometric parameters among Isfahan Young adults
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Alavi Sh. Assistant Professor
2003-06-01
Full Text Available Statement of Problem: Anthropometry is applied in medical professions such as maxillofacial surgery,"ngrowth and development studies, plastic surgery, bioengineering and non- medical branches such as like"nshoe- making and eye- glasses industries."nAim: The aim of the present study was to determine facial and cranial ratios among Isfahan young"nadults."nMaterials and Methods: A study was done randomly on 200 boys and 200 girls, from among Isfahan"nyoung adults, with normal face patterns. Facial and cranial ratios, according to sex, were estimated and"ncompared."nResults: The results of this study were compared with Canadian anthropometric findings by Farkas."nThere was no significant difference in cranial width between boys and girls but cranial length and all"nfacial parameters (Int ,cant, go-go, zy- zy, ch-ch, Ala-Ala, low.lip, Up.Iip, Sn.gn, Sto.gn, N.sto, Ngn"nwere greater in boys than girls. Cranial index and , , " ,Cl ratios were greater in"nn - gn zy - zy zy - zy zy - zy"n... slo-go sn-gn sto-gn slo-gn sto-gn . . ._"ngirls, however, -, -, , , were greater in boys, There was no significant"ngo-go n- gn n- gn n- sto sn - gn"ndifference about facial index between boys and girls. Comparing facial parameters between Iranian and Canadian races, low. lip, Ala-Ala and go- go were greater among Iranians, however, Int cant ,Up. lip. N.gn, ch- ch, zy-zy showed a greater size among Canadians. Sn-gn ratio was greater in Canadian girls, but there was no significant difference between Iranian and Canadian boys in this"nregard. " " s" , s° " 8° , " ~ s ° , g° " 8° , ^-- ratios were greater among Isfahanian boys and girls,"nzy-zy zy-zy zy-zy n - gn zy-zy"nhowever, J ° ~ g" , 5 ° " 8" / ° " s" ratios were greater among Canadians. Regarding 5"~g" ratio, no"nn- sto sn- gn n~ gn n- gn"nsignificant difference was observed between Canadian and Isfahanian girls."nConclusion: Considering the significant difference in the facial and cranial anthropologic
The incidence of dyslexia among young offenders in Kuwait.
Elbeheri, Gad; Everatt, John; Al Malki, Mohammad
2009-05-01
This paper investigates the incidence of dyslexia among young offenders in Kuwait. A total of 91 children/young adults from 8 juvenile delinquent welfare centres across Kuwait were interviewed and tested. A measure of non-verbal reasoning ability was used to exclude those with low general ability. The remaining 53 participants were tested on their ability to identify alliteration and rhyme, retain and manipulate sequences of digit and letter names, decode novel letter strings and identify words within letter chains. Participants' reading accuracy, rate of reading, reading comprehension and ability to spell correctly dictated text were also assessed. These measures were used to determine those with indicators of dyslexia. The results indicated that the percentage of individuals presenting evidence of dyslexia was much larger (greater than 20%) in this population of young offenders than would be expected based on the national average (around 6%) of dyslexics in Kuwait derived from a nationwide study (A survey study of dyslexia in Kuwait, Kuwait Dyslexia Association: Kuwait City; 2002). These findings replicate previous evidence for an increased frequency of dyslexia among young offenders. The implications of such findings are discussed in terms of dyslexia awareness, socio-cultural factors, education and intervention, particularly in Kuwait juvenile delinquent welfare centres.
The levels of bioelements in the saliva and hair of young athletes
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N. A. Troegubova
2016-01-01
Full Text Available The salivary and hair levels of bioelements, such as calcium, potassium, magnesium, iron, zinc, chromium, and selenium, were investigated in 130 children and adolescents, including 35 swimmers, 47 hockey players, 20 fencers, and 28 schoolchildren who did not additionally go in for sports. Atomic emission spectrometry and inductively coupled plasma mass spectrometry were applied. The aim of our study was to investigate the characteristics of macro- and microelemental composition of the saliva and hair of young athletes. The investigation established that that all young athletes showed the high levels of potassium and selenium in their hair, those of selenium and chromium in the saliva, and a significantly low concentration of potassium in the saliva (p<0,05, reflecting the intensity of mineral exchange during physical exercises. Individual characteristics were found in the content of chemical elements in the test biological substrates in relation to the kind of sports: the salivary levels of calcium and magnesium were reduced and the hair level of iron was increased in fencers (p<0,05; and the field-hockey players had higher zinc values (p<0,05. Comparison of the hair and salivary concentrations of bioelements established that there was a statistically significant relationship for potassium (R=-0,72; p<0,001 and selenium (R=0,44; p=0,004. Non-invasive screening studies of salivary and hair minerals are recommended for the early diagnosis of an imbalance in macro- and microelements in young athletes. There is evidence that young athletes should be identified as a group of patients at risk for an imbalance of macro- and microelements.
Young people and ICT – materials shaping resource-intensive practices?
DEFF Research Database (Denmark)
Christensen, Toke Haunstrup; Rommes, Els
2016-01-01
The extensive use of information and communication technology (ICT) in everyday practices results in increasing levels of consumption of energy and materials. Academics, NGOs and policymakers are beginning to address this issue and develop policies and campaigns to promote “sustainable” use of ICT....... The use of ICT is particularly widespread among young people, and this paper investigates the practices related to young people’s use of ICT. More specifically, we focus on the use of smart phones and laptops. The paper focuses on how the material qualities of smart phones, laptops and their related...... of ICT. Theoretically, the paper will apply a practice theoretical approach with STS concepts that bring the role of materials in shaping practices to the fore. In particular, we will draw on the Madeline Akrichs (1992) concept of (design) scripts. The analysis is based on focus groups with young people...
Nicholls, Wendy; Patterson, Pandora; McDonald, Fiona E J; Hulbert-Williams, Nicholas J
2017-03-01
Given the high number of young adults caring for a family member, and the potential for adverse psychosocial outcomes, there is a need for a screening tool, with clinical utility, to identify those most vulnerable to poor outcomes and to aid targeted interventions. (i) To determine whether current knowledge from cancer literature regarding young carers is generalisable to chronic conditions and, therefore, whether an existing screening tool could be adapted for this population. (ii) To develop a measure of unmet needs in this population and conduct initial psychometric analysis. This was mixed method; interviews in study one informed measure development in study two. Inclusion criteria were as follows: having a parent with a chronic condition and being aged 16-24 years. In study 1, an interpretative phenomenological analysis was conducted on interviews from seven young adults (age range 17-19 years). Study 2 explored factor structure, reliability and validity of the Offspring Chronic Illness Needs Inventory (OCINI). Participants were 73 females and 34 males (mean ages 18.22, SD = 1.16; 18.65, SD = 1.25). OCINI, Depression Anxiety and Stress Scale, and the Adult Carers Quality of Life Scale. Interviews communicated that the impact of their parent's condition went unacknowledged and resulted in psychosocial, support and informational needs. An exploratory principal axis analysis of the OCINI yielded five factors. Significant and positive correlations were found between unmet needs and stress, anxiety, and depression, and inversely with quality of life. The scale has applications in clinical settings where these young people, who are at risk of negative psychological outcomes, may be assessed and unmet needs targeted appropriately. © 2016 Nordic College of Caring Science.
Indoor Tanning Dependence in Young Adult Women.
Mays, Darren; Atkins, Michael B; Ahn, Jaeil; Tercyak, Kenneth P
2017-11-01
Background: There is mounting evidence that young people can develop a dependence on indoor tanning, but research on factors associated with indoor tanning dependence remains limited. Methods: This cross-sectional study investigated factors associated with indoor tanning dependence in a community sample of 389 non-Hispanic white young adult women ages 18 to 30 who had indoor tanned ≥1 time in the past year. Participants completed measures of indoor tanning dependence, including the modified CAGE and modified Diagnostic and Statistical Manual for Mental Disorders-IV psychiatric screening assessments, indoor tanning behavior and beliefs, and behavioral and psychiatric comorbidity. Results: Overall, 22.6% of the sample screened positive for indoor tanning dependence. In multivariable analyses, indoor tanning dependence was associated with younger age of indoor tanning initiation [adjusted odds ratio (aOR) = 0.79; P = 0.017], indoor tanning ≥20 times in the past year (aOR = 3.03; P = 0.015), stronger beliefs about the benefits of tanning (aOR = 2.15; P = 0.004), greater perceived susceptibility to indoor tanning risks (aOR = 2.72; P tanning dependence among young, non-Hispanic white women is associated with behaviors that increase the risk of skin cancer, beliefs favoring the perceived benefits of tanning, and comorbid risks such as stronger beliefs about physical appearance and depressed mood. Impact: Comprehensive skin cancer prevention efforts should address indoor tanning dependence among young women and its leading risk factors. Cancer Epidemiol Biomarkers Prev; 26(11); 1636-43. ©2017 AACR . ©2017 American Association for Cancer Research.
Witvliet, Margot I.; Arah, Onyebuchi A.; Stronks, Karien; Kunst, Anton E.
2014-01-01
Poor health is more prevalent in the east of Europe as compared with the west. This variation is often attributed to Soviet communism. Few studies investigate this health discrepancy within young adults who were children during this period. We studied the health of young adults by examining
Reading to Young Children : A Head-Start in Life?
Kalb, G.; van Ours, J.C.
2013-01-01
Abstract: This paper investigates the importance of parents reading to their young children. Using Australian data we find that parental reading to children at age 4 to 5 has positive and significant effects on reading skills and cognitive skills of these children at least up to age 10 or 11. Our
Davies, Michael D.; Beamish, Wendi
2009-01-01
Background: Few studies have investigated transition programs and outcomes for young adults with disabilities as viewed from the parent perspective. The current Australian study provided a voice for parents to report on the experiences of and outcomes for young adults following their recent transition from school into post-school life. Method: A…
Health promotion for young people with profound and multiple learning disabilities.
Davis, Kathy; Carter, Simone; Myers, Elizabeth; Rocca, Nicola
2018-02-07
Research confirms that children and young people with severe learning disabilities do not have the same level of access to high-quality care, health education and health promotion activities as children and young people without disabilities. This article discusses a quality improvement, action research project to investigate alternative approaches to health promotion that enhance the health and well-being of children and young people with complex neurodisabilities. The project involved assessment of school records and completion by staff of an eight-question survey. It found that the proactive approach of school nurses in raising awareness and understanding through questioning was positively received, and reinforced how meaningful and relevant information could be delivered to these young people. The project also had unexpected benefits, including more integrated team working, increased knowledge, greater awareness and understanding of the importance of health promotion participation, and student satisfaction. ©2018 RCN Publishing Company Ltd. All rights reserved. Not to be copied, transmitted or recorded in any way, in whole or part, without prior permission of the publishers.
Directory of Open Access Journals (Sweden)
Nishihara K
2014-09-01
Full Text Available Ken Nishihara,1 Hisashi Kawai,2 Hiroyuki Hayashi,3 Hideo Naruse,4 Akihito Kimura,4 Toshiaki Gomi,5 Fumihiko Hoshi1 1Department of Physical Therapy, Saitama Prefectural University, Saitama, Japan; 2Health Promotion Management Office, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan; 3Center for University-wide Education, Saitama Prefectural University, Saitama, Japan; 4Faculty of Health Sciences, Tokyo Ariake University of Medical and Health Sciences, Tokyo, Japan, 5Faculty of Nursing, Tokyo Ariake University of Medical and Health Sciences, Tokyo, Japan Background: The skeletal muscle echo intensity (EI during ultrasound imaging has been investigated to evaluate the muscle quality. However, EI fluctuates according to the scanning conditions.Methods: The motor functions and ultrasound images of 19 elderly (73±3.2 years and 19 young (22±1.5 years individuals were investigated and an EI frequency component was assessed for more reliable evaluations. Healthy elderly and young subjects participated in this study. The motor functions were assessed during walking and according to the knee extension muscle strength. The muscle thicknesses of rectus femoris (RF, vastus intermedius (VI, and quadriceps femoris (QF were investigated. EIs were calculated and the mean frequencies of the regions of interest (MFROIs for RF and VI were analyzed. Results: EIs and MFROIs were greater in elderly subjects than in young subjects (P<0.01 for RF, and P<0.001 for VI, in EIs; and P<0.01 for RF, and P<0.05 for VI, in MFROIs. In young subjects, EI of RF was greater than that of VI; however, there was no difference between the RF and VI MFROIs in both elderly and young subjects. EIs of VI exhibited a significantly negative correlation with the QF thickness in both elderly and young subjects. RF MFROIs negatively correlated with the QF thickness and positively correlated with EI of VI in elderly subjects alone. Conclusion: These findings
Sustainable healthy eating behaviour of young adults: towards a novel methodological approach.
Pieniak, Zuzanna; Żakowska-Biemans, Sylwia; Kostyra, Eliza; Raats, Monique
2016-07-15
Food, nutrition and health policy makers are poised with two pertinent issues more than any other: obesity and climate change. Consumer research has focused primarily on specific areas of sustainable food, such as organic food, local or traditional food, meat substitution and/or reduction. More holistic view of sustainable healthy eating behaviour has received less attention, albeit that more research is emerging in this area. This study protocol that aims to investigate young consumers' attitudes and behaviour towards sustainable and healthy eating by applying a multidisciplinary approach, taking into account economical, marketing, public health and environmental related issues. In order to achieve this goal, consumers' reactions on interactive tailored informational messages about sustainable from social, environmental and economical point of view, as well as healthy eating behaviour in a group of young adults will be investigated using randomized controlled trial. To undertake the objective, the empirical research is divided into three studies: 1) Qualitative longitudinal research to explore openness to adopting sustainable healthy eating behaviour; 2) Qualitative research with the objective to develop a sustainable healthy eating behaviour index; and 3) Randomised controlled trial to describe consumers' reactions on interactive tailored messages about sustainable healthy eating in young consumers. To our knowledge, this is the first randomised controlled trial to test the young adults reactions to interactive tailor made messages on sustainable healthy eating using mobile smartphone app. Mobile applications designed to deliver intervention offer new possibilities to influence young adults behaviour in relation to diet and sustainability. Therefore, the study will provide valuable insights into drivers of change towards more environmentally sustainable and healthy eating behaviours. NCT02776410 registered May 16, 2016.
The sex disparity in risky driving: A survey of Colombian young drivers.
Oviedo-Trespalacios, Oscar; Scott-Parker, Bridie
2018-01-02
The overrepresentation of young drivers in poor road safety outcomes has long been recognized as a global road safety issue. In addition, the overrepresentation of males in crash statistics has been recognized as a pervasive young driver problem. Though progress in road safety evidenced as a stabilization and/or reduction in poor road safety outcomes has been made in developed nations, less-developed nations contribute the greatest road safety trauma, and developing nations such as Colombia continue to experience increasing trends in fatality rates. The aim of the research was to explore sex differences in self-reported risky driving behaviors of young drivers, including the associations with crash involvement, in a sample of young drivers attending university in Colombia. The Spanish version of the Behaviour of Young Novice Drivers Scale (BYNDS-Sp) was applied in an online survey to a sample of 392 students (225 males) aged 16-24 years attending a major university. Appropriate comparative statistics and logistic regression modeling were used when analyzing the data. Males reported consistently more risky driving behaviors, with approximately one quarter of all participants reporting risky driving exposure. Males reported greater crash involvement, with violations such as speeding associated with crash involvement for both males and females. Young drivers in Colombia appear to engage in the same risky driving behaviors as young drivers in developed nations. In addition, young male drivers in Colombia reported greater engagement in risky driving behaviors than young female drivers, a finding consistent with the behaviors of young male drivers in developed nations. As such, the research findings suggest that general interventions such as education, engineering, and enforcement should target transient rule violations such as speeding and using a handheld mobile phone while driving for young drivers in Colombia. Future research should investigate how these
Attention Deficit Hyperactivity Disorder Medication Use Among Teens and Young Adults.
Johansen, Michael E; Matic, Kathleen; McAlearney, Ann Scheck
2015-08-01
The purpose of this study was to determine rates of stimulant/atomoxetine use among teens (aged 12-17 years) and young adults (aged 18-23 years) and to investigate associations in medication use before and after the transition from teen to young adult. Repeated cross-sectional analyses using the nationally representative Medical Expenditure Panel Survey. The sample included all teens and young adults between 2003 and 2012. Within this group, a staggered sample of individuals between 2006 and 2012 born during a 5-year range was used to minimize false positive findings due to temporal trends. The primary outcome was attention deficit hyperactivity disorder (ADHD) medication use (two or more prescriptions and ≥60 tablets). A multivariable logistic regression was utilized to determine associations between ADHD medication use and race/ethnicity and other sociodemographic factors. A total of 62,699 individuals were included between 2003 and 2012. Rates of ADHD medication use increased for both teens (4.2%-6.0%) and young adults (1.2%-2.6%) between 2003-2004 and 2011-2012. In adjusted analysis, blacks, Hispanics, and Asians had lower rates of use compared with whites. The decrease in use among young adults was more pronounced among blacks compared with whites. A usual source of care and health insurance were less common among young adults, and both were associated with ADHD medication use. Although there has been an increase in the use of ADHD medications in both teens and young adults, we found a drop-off in levels of ADHD treatment among young adults when compared with teens. A portion of this decrease appears to be related to race/ethnicity, usual source of care, and health insurance status. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
Stigmatisation of a Formerly Obese Young Female
Tucci, Sonia A.; Boyland, Emma J.; Halford, Jason C.G.; Harrold, Joanne A.
2013-01-01
Background Weight loss does not necessarily decrease the negative appraisal of a formerly overweight individual. Since past weight history tends to be disclosed in several contexts, this study aims to investigate whether negative appraisals are gender-specific and if they are modulated by the evaluators’ own BMI. Methods 202 young adults (106 male and 96 female) viewed a picture of a young attractive female (target) accompanied by one of two statements about her past weight (overweight (OW) or always kept a normal weight (NW)), and then rated her using the Fat Phobia Scale (FPS). Results Female evaluators rated the target with the OW statement more negatively than the target with the NW statement. In contrast, males exposed to the OW statement rated the target as having fewer emotional/psychological problems and being less stupid/uncreative. BMI only influenced ratings in males, where those with higher BMI ascribed more negative attributes to the target with the NW statement than the OW statement. Conclusion Information on weight history impacts upon the appraisal of peers. These effects are dependent on gender and BMI. Knowing that a young female was overweight triggered negative evaluations from females but did not appear to impact the judgment of males. PMID:24107842
Stigmatisation of a Formerly Obese Young Female
Directory of Open Access Journals (Sweden)
Sonia A. Tucci
2013-10-01
Full Text Available Background: Weight loss does not necessarily decrease the negative appraisal of a formerly overweight individual. Since past weight history tends to be disclosed in several contexts, this study aims to investigate whether negative appraisals are gender-specific and if they are modulated by the evaluators' own BMI. Methods: 202 young adults (106 male and 96 female viewed a picture of a young attractive female (target accompanied by one of two statements about her past weight (overweight (OW or always kept a normal weight (NW, and then rated her using the Fat Phobia Scale (FPS. Results: Female evaluators rated the target with the OW statement more negatively than the target with the NW statement. In contrast, males exposed to the OW statement rated the target as having fewer emotional/psychological problems and being less stupid/uncreative. BMI only influenced ratings in males, where those with higher BMI ascribed more negative attributes to the target with the NW statement than the OW statement. Conclusion: Information on weight history impacts upon the appraisal of peers. These effects are dependent on gender and BMI. Knowing that a young female was overweight triggered negative evaluations from females but did not appear to impact the judgment of males.
Breast cancer of young women - case report
International Nuclear Information System (INIS)
Slobodnikova, J.
2013-01-01
Introduction: Breast cancer is the most common malignancy of the female population, the incidence is increasing mainly statistically between 50. a 60s, 60s and 70s. Recently, however, we meet more often with the occurrence of breast cancer in women in 30 year and significantly between 30 and 40 year. Cases: The following are examples of four young women who had different symptoms who failed primary diagnosis was revalued the importance of sonography and age, did not think the possibility of the presence of cancer. Results: The patients presented were finally correctly diagnosed, treated with a relatively good prognosis. Their diagnosis, however, could be faster and smaller tumors. However, despite the fact that Slovakia has enacted preventive investigation of the breast young women from the 20 to 40th of clinically and sonographically, encountered in practice, often with cases of breast cancer diagnosed late. Conclusion: Case report we highlight the diversity of clinical symptoms and the possibility of imaging diagnostic techniques in the diagnosis of breast disease of young women. We also want to draw attention to some underestimation of clinical symptoms, while revaluation results of sonographic examinations. An important factor is the quality of the ultrasound device and effective consultation and cooperation with other diagnostic departments. (author)
Zheng, Naiyu; Zeng, Jianing; Manney, Amy; Williams, Lakenya; Aubry, Anne-Françoise; Voronin, Kimberly; Buzescu, Adela; Zhang, Yan J; Allentoff, Alban; Xu, Carrie; Shen, Hongwu; Warner, William; Arnold, Mark E
2016-04-15
To quantify a therapeutic PEGylated protein in monkey serum as well as to monitor its potential in vivo instability and methionine oxidation, a novel ultra high performance liquid chromatography-high resolution mass spectrometric (UHPLC-HRMS) assay was developed using a surrogate disulfide-containing peptide, DCP(SS), and a confirmatory peptide, CP, a disulfide-free peptide. DCP(SS) was obtained by eliminating the step of reduction/alkylation before trypsin digestion. It contains an intact disulfide linkage between two peptide sequences that are essential for drug function but susceptible to potential in vivo cleavages. HRMS-based single ion monitoring (SIM) on a Q Exactive™ mass spectrometer was employed to improve assay specificity and sensitivity for DCP(SS) due to its poor fragmentation and low sensitivity with SRM detection. The assay has been validated for the protein drug in monkey serum using both surrogate peptides with excellent accuracy (within ±4.4%Dev) and precision (within 7.5%CV) with a lower limit of quantitation (LLOQ) at 10 ng mL(-1). The protein concentrations in monkey serum obtained from the DCP(SS)-based assay not only provided important pharmacokinetic parameters, but also confirmed in vivo stability of the peptide regions of interest by comparing drug concentrations with those obtained from the CP-based assay or from a ligand-binding assay (LBA). Furthermore, UHPLC-HRMS allowed simultaneous monitoring of the oxidized forms of both surrogate peptides to evaluate potential ex vivo/in vivo oxidation of one methionine present in each of both surrogate peptides. To the best of our knowledge, this is the first report of using a surrogate disulfide-containing peptide for LC-MS bioanalysis of a therapeutic protein. Copyright © 2016 Elsevier B.V. All rights reserved.
Circumvention of suddenly appearing obstacles in young and older adults
Pijnappels, M.; Kingma, I.; Van Dieën, J. H.
2010-01-01
Reduced ability to circumvent an obstacle, which is noticed only shortly before collision, could be a cause of falls and injury, especially in older adults. In this study, we investigated differences in strategies and their characteristics between young and older adults when circumventing a suddenly
Flies selected for longevity retain a young gene expression profile
DEFF Research Database (Denmark)
Sarup, Pernille Merete; Sørensen, Peter; Loeschcke, Volker
2011-01-01
We investigated correlated responses in the transcriptomes of longevity-selected lines of Drosophila melanogaster to identify pathways that affect life span in metazoan systems. We evaluated the gene expression profile in young, middle-aged, and old male flies, finding that 530 genes were...
A CLINICAL STUDY OF STROKE IN YOUNG
Directory of Open Access Journals (Sweden)
Kumbha Thulasi Ram
2015-02-01
Full Text Available NTRIDUCTION : Stroke is one of the important causes of morbidity and mortality all over the world. Incidence of stroke steadily increases with age. Experts are concerned of the emerging stroke epidemic in India. Stroke affecting the young has potentially devastating consequence son the individual and his family. Certain risk factors are unique to the young. I t needs more studies for identification and modification of risk factors. The study aims to evaluate clinical features, risk factors, etiology and mortality of stroke in young patients. METHODS : 74 young patients satisfying the inclusion criteria were included in this study. A detailed history was taken from young stroke patients, systemic examination and required investigations were done. Data was collected in standardized proforma and analysed. RESULTS: Stroke in young accounts for 7.95% of stroke cases of all age groups. The mean age of the patients was 34.66 ± 7.48 years. Among 74 patients, 47(63.51% were male and 27(36.49% were female. Seizures, decreased consciousness, speech involvement and motor deficit were observed in 33.78%, 44.59%, 22.97% and 100% of cases respectively. 82.43% patients had ischemic and 17.57% patients had hemorrhagic stroke. Among ischemic stroke, large artery atherosclerosis was 16.21%, tuberculous meningoencephalitis with vasculitis was 16.21%, lacunar stroke was 10.81%, CVT was 10.81% and cardio embolic stroke was 6.76%. Smoking (59.45%, alcoholism (58.10%, hypertension (43.24%, coronary artery disease (8.10%, diabetes mellitus (10.81%, elevated total cholesterol (25.67%, elevated low density lipo proteins (22.97%, elevated triglycerides (27.02% and low HDL (22.97% were important risk factors. Carotid doppler was abnormal in 9.45% of patients. 6.76% patients had mitral stenosis in echocardiogram. Low protein C and protein S were found in 1.35% of patients. Eight (10.81% patients died during the hospital stay. INTERPRETATION AND CONCLUSIONS: The major risk
Gonzalez, Jodi M.; Alegria, Margarita; Prihoda, Thomas J.
2005-01-01
This article investigates attitudes toward seeking mental health treatment in a national epidemiological sample. Young adults reported the most negative attitudes, as compared to older adults. Males reported more negative attitudes, as compared to females, a consistent finding in young adults. The gender difference was not consistent in Latinos…
Exploring the safety implications of young drivers' behavior, attitudes and perceptions.
Hassan, Hany M; Abdel-Aty, Mohamed A
2013-01-01
The present study aims at identifying and quantifying significant factors (i.e., demographic, aberrant driving behavior) associated with young drivers' involvement in at-fault crashes or traffic citations at the ages of 16-17 (while having the Operational License) and 18-24 years old (while having the Full License). A second objective was to investigate the main reason(s) for involvement in risky driving behavior by young drivers. The data used for the analyses were obtained from a self-reported questionnaire survey carried out among 680 young drivers in Central Florida. To achieve these goals, the structural equation modeling approach was adopted. The results revealed that aggressive violations, in-vehicle distractions and demographic characteristics were the significant factors affecting young drivers' involvement in at-fault crashes or traffic violations at the age of 16-17. However, in-vehicle distractions, attitudes toward speeding and demographic characteristics were the significant factors affecting young drivers' crash risk at 18-24. Additionally, the majority of participants reported that "running late" is the main reason for taking risk while driving (i.e., speeding, accept short gaps, or drive so close to the car in front) followed by "racing other cars". Additionally, "exceed speed limits" was the main reason for receiving traffic citations at 16-17 and 18-24 age groups. Practical suggestions on how to reduce crash risk and promote safe driving among young drivers are also discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.
Incidence of Stingers in Young Rugby Players.
Kawasaki, Takayuki; Ota, Chihiro; Yoneda, Takeshi; Maki, Nobukazu; Urayama, Shingo; Nagao, Masashi; Nagayama, Masataka; Kaketa, Takefumi; Takazawa, Yuji; Kaneko, Kazuo
2015-11-01
A stinger is a type of neurapraxia of the cervical roots or brachial plexus and represents a reversible peripheral nerve injury. The incidence of and major risk factors for stingers among young rugby players remain uninvestigated. To investigate the incidence, symptoms, and intrinsic risk factors for stingers in elite rugby union teams of young players. Descriptive epidemiology study. A total of 569 male rugby players, including 358 players from 7 high school teams and 211 players from 2 university teams, were investigated using self-administered preseason and postseason questionnaires. The prevalence of a history of stingers was 33.9% (95% CI, 30.3-37.9), and 20.9% (119/569) of players experienced at least 1 episode of a stinger during the season (34.2 [95% CI, 26.2-42.1] events per 1000 player-hours of match exposure). The reinjury rate for stingers per season was 37.3% (95% CI, 30.4-44.2). Using the multivariate Poisson regression method, a history of stingers in the previous season and the grade and position of the player were found to be risk factors for stingers during the current season. The mean severity of injury was 2.9 days, with 79.3% (191/241) of the players not losing any time from playing after sustaining a stinger injury and 5.8% (14/241) of the players recovering within more than 14 days. The most frequent symptom was numbness in the unilateral upper extremity, and the most severe symptom was weakness of grasping (mean severity, 6 days). A logistic regression analysis indicated that a history of stingers in the previous season and an injury with more than 3 symptoms, especially motor weakness, were correlated with the severity of injury. Young rugby players with a history of stingers have a significantly high rate of repeat injuries. Although nearly 80% of the players experienced only minimal (0-1 day) time loss injuries, neurological deficits sometimes last beyond 1 month. A history of stingers was identified to be the strongest risk factor for
Witte, Kenneth L.; Freund, Joel S.
1976-01-01
Investigated the learning of young and old adults as related to two variables, stimulus concreteness (low vs. high) and presentation method (recall vs. multiple choice vs. associate matching). Main findings were: (a) the elderly did not perform as well as young adults, (b) for both groups, performance was better for the pairs with concrete…
A typology of alcohol consumption among young people
DEFF Research Database (Denmark)
Davoren, M.P.; Cronin, M; Perry, I.J.
2016-01-01
information from studies that produced types of alcohol consumption among young people. Method Quantitative and qualitative literature investigating the different types of drinkers among young people [aged 12–24 years], published in peer reviewed journals, were eligible for inclusion in this systematic review...... In total, 13 studies were eligible for inclusion: 11 quantitative, one qualitative and one mixed methods. Six classes of drinkers were formed within this typology. Abstainers reported no alcohol consumption. Light drinkers reported drinking small amounts of alcohol infrequently. In comparison, social......Background Currently, alcohol consumption levels are significantly higher among younger age groups. However, previous research has noted the diversity of motivations and patterns. These patterns of drinking have yet to be synthesised into a typology. The aim of the current study was to synthesise...
"When you're desperate you'll ask anybody": young people's social sources of tobacco.
Marsh, Louise; Dawson, Anna; McGee, Rob
2013-04-01
This study sought to examine young New Zealand smokers' access to social supplies of cigarettes. A qualitative investigation using 10 focus groups with 66 current young smokers, aged between 15 and 17 years, was conducted throughout New Zealand, between October and December 2011. Transcripts from the focus groups were analysed using NVivo to code the data, from which common themes and critical issues were identified. Family was one of the main sources of tobacco for the young smokers in this study and parents were the leading source, often purchasing tobacco for their children to smoke. Sharing tobacco within groups of friends was also very common. Additional methods were used when young smokers were desperate, including stealing, 'butt scabbing' and asking strangers. Both family and social networks continue to support smoking and supply tobacco to young people. While these networks operate, young people will continue to smoke, despite increased regulations on commercial sales to minors. Restrictions on commercial sales of tobacco to minors are increasing; however, many young people use multiple sources of tobacco, including social sources. It is likely that young people will increasingly use these social sources in the future. Interventions other than purchase restrictions are important for reducing minors' access to tobacco. © 2013 The Authors. ANZJPH © 2013 Public Health Association of Australia.
Economic Conditions of Young Adults Before and After the Great Recession.
Sironi, Maria
2018-01-01
Transition to adulthood has undoubtedly changed in the last few decades. For youth today, an important marker of adulthood is self-actualization in their professional career, and, consequently, also the achievement of stable financial conditions. Economic conditions of youth are greatly subject to fluctuations in the economy, and the subsequent governmental response. Using the Luxembourg Income Study, this work investigates the trends in income from work of young adults before and after the Great Recession of 2008 in five countries-US, UK, Norway, Germany, and Spain. The findings showed deterioration in economic conditions of young men, but with differences across countries. Young women suffered less from the crisis, and in some countries, their economic situation improved. The general negative trend was especially pronounced for those with high education, which is primarily because they stayed in education longer.
Gastrointestinal mean transit times in young and middle-aged healthy subjects
DEFF Research Database (Denmark)
Graff, J; Brinch, K; Madsen, Jan Lysgård
2001-01-01
To investigate the effects of age and gender on gastric, small intestinal and colonic mean transit times, a study was conducted in 32 healthy volunteers: eight young women (22-30 years), eight young men (20-28 years), eight middle-aged women (43-51 years) and eight middle-aged men (38-53 years......, small intestinal and colonic mean transit times were calculated. The gastric, small intestinal and colonic mean transit times were significantly longer in women. Ageing was shown to accelerate the gastric and small intestinal transit significantly. In the group of men the colonic mean transit time...... was unaffected by age, but middle-aged women had a significantly slower colonic transit than young women. We therefore conclude that both age and gender have to be considered when reference values for gastric, small intestinal and colonic mean transit times have to be established....
Young people, new media and sport
Wong, Donna Shy Yun
2009-01-01
This thesis investigates how sport is employed in the new media age as mediated sport goes through the liminal phase of new media. Set against the contextual background of recurrent ‘moral panics’ that accompanied each new wave of media innovation, this study aimed to chart young people’s involvement in sport via the use of new media technology. The thesis concentrated on three research issues: access to, uses of, and the displacement effect of new media. Four major forms of ne...
Ischemic stroke in young adults: an overview of etiological aspects
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Fábio Iuji Yamamoto
2012-06-01
Full Text Available Stroke affects mainly people aged over 65 years, and atherosclerosis predominates as the main etiopathogenic factor in ischemic stroke (IS. On the other hand, cardiac embolism and arterial dissection are the most frequent causes of IS in patients aged less than 45 years. However, inappropriate control of traditional vascular risk factors in young people may be causing a significant increase of atherosclerosis-related IS in this population. Furthermore, a variety of etiologies, many of them uncommon, must be investigated. In endemic regions, neurocysticercosis and Chagas' disease deserve consideration. Undetermined cause has been still reported in as many as one third of young stroke patients.
The Consumer Behaviour of Taiwanese Young People: With Respect to Luxury Brand Products
Li, Wei-Hsuan
2006-01-01
In recent years, there is a fever of buying and using luxury brand products in Taiwanese young generation. Young people are feverish to purchase expensive and luxury goods from those famous international luxury brands. This dissertation aims to investigate this phenomenon in depth. The study could be generally divided into six parts. First of all, the main concept and objectives of this research will be introduced. Next, the background of luxury goods industry will be presented. Besides,...
MAJOR INJURIES MUSCULOSKELETALS IN YOUNG ATHLETES BASKETBALL
Directory of Open Access Journals (Sweden)
José Simão Rodrigues Filho
2012-11-01
Full Text Available The growth of participation of youth in sports is accompanied by an increase in the number of musculoskeletal injuries, especially in contact sports. Basketball gained prominence among contact sports not only for its plastic and beauty of their games, but because it is a sport that demands much of its practitioners, and in the case of young athletes, this requirement can endanger children and adolescents are not properly monitored for health professionals sports. In this study we can see that the ankle is the most affected, followed by knee and fingers and wrists. The mechanisms of injury most frequently reported were sprains, after the bruises and fractures. Highlight for disturbances dorsolumbar, pointed out by many authors. The prevention programs and pre-competition oriented properly treated as paramount by all the authors investigated, in order to reduce the number of injuries in young athletes.
2013-01-01
In The Netherlands, young novice drivers (18-24 years of age) show a crash rate that is five times higher than that of experienced drivers (30-59 years of age). The rate of young males is even seven times as high. The main reasons are lack of driving experience and hazardous behaviour typical of
Boukhanovsky, A.V.; Ilyin, V.A; Krzhizhanovskaya, V.V.; Athanassoulis, G.A.; Klimentov, A.A.; Sloot, P.M.A.
2015-01-01
We present an annual international Young Scientists Conference (YSC) on computational science http://ysc.escience.ifmo.ru/, which brings together renowned experts and young researchers working in high-performance computing, data-driven modeling, and simulation of large-scale complex systems. The
Özbek, Emel; Bongers, Ilja L; Lobbestael, Jill; van Nieuwenhuizen, Chijs
2015-12-01
This study investigated the relationship between acculturation and psychological problems in Turkish and Moroccan young adults living in the Netherlands. A sample of 131 healthy young adults aged between 18 and 24 years old, with a Turkish or Moroccan background was recruited using snowball sampling. Data on acculturation, internalizing and externalizing problems, beliefs about psychological problems, attributions of psychological problems and barriers to care were collected and analyzed using Latent Class Analysis and multinomial logistic regression. Three acculturation classes were identified in moderately to highly educated, healthy Turkish or Moroccan young adults: integration, separation and diffusion. None of the participants in the sample were marginalized or assimilated. Young adults reporting diffuse acculturation reported more internalizing and externalizing problems than those who were integrated or separated. Separated young adults reported experiencing more practical barriers to care than integrated young adults. Further research with a larger sample, including young adult migrants using mental health services, is required to improve our understanding of acculturation, psychological problems and barriers to care in this population. Including experiences of discrimination in the model might improve our understanding of the relationship between different forms of acculturation and psychological problems.
Self-management in young adults with bipolar disorder: Strategies and challenges.
Nicholas, Jennifer; Boydell, Katherine; Christensen, Helen
2017-02-01
Early adoption of effective self-management strategies for bipolar disorder (BD) results in better clinical outcomes and increased quality of life. Therefore, facilitation of these strategies in young adults who are early in their illness course is vital. However, an understanding of self-management practices and needs of young adults with BD is lacking. This study explores young adult's perspectives of disorder self-management practices and challenges. Young adults with BD completed an online survey about disorder management strategies and challenges. Self-management was investigated through self-report and ratings of literature-derived strategies. Results were analysed using descriptive statistics and qualitative thematic analysis. Eighty-nine participants aged 18-30 (M=24.4; SD=3.9) completed the survey. Adherence to treatment, disorder psychoeducation, and sleep-management were the strategies rated most helpful. Six participant-reported self-management strategies were identified (1) Maintaining a healthy lifestyle; (2) Treatment attendance and adherence; (3) Participation in meaningful activities; (4) Engagement with social support; (5) Meditation and relaxation practices; and (6) Symptom monitoring. The most common self-management challenges experienced by young adults concerned the nature of the disorder, interpersonal relationships, and stigma. Participants likely represent a sub-set of young adults engaged with healthcare and therefore may not be representative of the population. Strategies reported vital by those successfully managing their disorder are not adequately utilised by young adults with BD. Both differences in strategy use and perceived self-management challenges represent important areas of clinical support and intervention. This increased understanding will help facilitate self-management skill development in this population. Copyright © 2016 Elsevier B.V. All rights reserved.
Rakap, Salih; Parlak-Rakap, Asiye; Aydin, Burak
2016-01-01
Inclusion of young children with disabilities into general education classrooms is a common practice that has been implemented for many years in developed countries around the world and many developing countries have been creating and implementing laws and regulations to support inclusive education in early years. Although extant literature…
A Review of Hazard Anticipation Training Programs for Young Drivers.
McDonald, Catherine C; Goodwin, Arthur H; Pradhan, Anuj K; Romoser, Matthew R E; Williams, Allan F
2015-07-01
Poor hazard anticipation skills are a risk factor associated with high motor vehicle crash rates of young drivers. A number of programs have been developed to improve these skills. The purpose of this review was to assess the empirical literature on hazard anticipation training for young drivers. Studies were included if they (1) included an assessment of hazard anticipation training outcomes; (2) were published between January 1, 1980 and December 31, 2013 in an English language peer-reviewed journal or conference proceeding; and (3) included at least one group that uniquely comprised a cohort of participants aged anticipation outcomes but none investigated crash effects. Although there is promise in existing programs, future research should include long-term follow-up, evaluate crash outcomes, and assess the optimal timing of hazard anticipation training taking into account the age and experience level of young drivers. Copyright © 2015 Society for Adolescent Health and Medicine. All rights reserved.
An investigation of strategies for integrated learning experiences ...
African Journals Online (AJOL)
(NCS, 2002) integrated music, dance, drama and visual arts where possible, while ... for the development of literacy skills, the latter term used by Wagner, ..... for movement ..... Qualitative investigation of young children's music preferences.
The Effect of Karate Practice on Self-Esteem in Young Adults with Visual Impairment: A Case Study
Qasim, Samir; Ravenscroft, John; Sproule, John
2014-01-01
Previous research has not examined the potential relationship between physical activity interventions and psychological domains of young adults with visual impairment (VI). This study aimed to investigate whether karate practice improves the self-esteem of young adults with VI. A secondary aim of this study was to explore the exercise and…
The implication of frontostriatal circuits in young smokers: A resting-state study.
Yuan, Kai; Yu, Dahua; Bi, Yanzhi; Li, Yangding; Guan, Yanyan; Liu, Jixin; Zhang, Yi; Qin, Wei; Lu, Xiaoqi; Tian, Jie
2016-06-01
The critical roles of frontostriatal circuits had been revealed in addiction. With regard to young smokers, the implication of frontostriatal circuits resting-state functional connectivity (RSFC) in smoking behaviors and cognitive control deficits remains unclear. In this study, the volume of striatum subsets, i.e., caudate, putamen, and nucleus accumbens, and corresponding RSFC differences were investigated between young smokers (n1 = 60) and nonsmokers (n2 = 60), which were then correlated with cigarette smoking measures, such as pack_years-cumulative effect of smoking, Fagerström Test for Nicotine Dependence (FTND)-severity of nicotine addiction, Questionnaire on Smoking Urges (QSU)-craving state, and Stroop task performances. Additionally, mediation analysis was carried out to test whether the frontostriatal RSFC mediates the relationship between striatum morphometry and cognitive control behaviors in young smokers when applicable. We revealed increased volume of right caudate and reduced RSFC between caudate and dorsolateral prefrontal cortex (DLPFC), orbitofrontal cortex in young smokers. Significant positive correlation between right caudate volume and QSU as well as negative correlation between anterior cingulate cortex-right caudate RSFC and FTND were detected in young smokers. More importantly, DLPFC-caudate RSFC strength mediated the relationship between caudate volume and incongruent errors during Stroop task in young smokers. Our results demonstrated that young smokers showed abnormal interactions within frontostriatal circuits, which were associated with smoking behaviors and cognitive control impairments. It is hoped that our study focusing on frontostriatal circuits could provide new insights into the neural correlates and potential novel therapeutic targets for treatment of young smokers. Hum Brain Mapp 37:2013-2026, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Shin, Wonsun; Ismail, Nurzali
2014-09-01
This study investigated the role of parental and peer mediation in young adolescents' engagement in risk-taking in social networking sites (SNSs). A survey conducted in Malaysia with 469 SNS users aged 13-14 revealed that control-based parental mediation can cause boomerang effects, making young adolescents more inclined to taking risks in SNSs. While discussion-based parental mediation was found to be negatively related to young adolescents' befriending strangers in SNSs, it did not reduce privacy risks. Findings also suggested that peer influence could result in undesirable outcomes. In particular, the more young adolescents talked about Internet-related issues with peers, the more likely they were to disclose personally identifiable information on SNSs.
The evolution of the Pharma-CRO working relationship: AstraZeneca and Covance.
2017-08-01
Christopher Bailey (AstraZeneca) and Lee Goodwin (Covance) speak to Sankeetha Nadarajah (Managing Commissioning Editor, Bioanalysis) about the evolution of the Pharma-CRO working relationship between AstraZeneca and Covance.
Abedi, Behzad; Abbasi, Ataollah; Goshvarpour, Atefeh
2017-05-01
In the past few decades, several studies have reported the physiological effects of listening to music. The physiological effects of different music types on different people are different. In the present study, we aimed to examine the effects of listening to traditional Persian music on electrocardiogram (ECG) signals in young women. Twenty-two healthy females participated in this study. ECG signals were recorded under two conditions: rest and music. For each ECG signal, 20 morphological and wavelet-based features were selected. Artificial neural network (ANN) and probabilistic neural network (PNN) classifiers were used for the classification of ECG signals during and before listening to music. Collected data were separated into two data sets: train and test. Classification accuracies of 88% and 97% were achieved in train data sets using ANN and PNN, respectively. In addition, the test data set was employed for evaluating the classifiers, and classification rates of 84% and 93% were obtained using ANN and PNN, respectively. The present study investigated the effect of music on ECG signals based on wavelet transform and morphological features. The results obtained here can provide a good understanding on the effects of music on ECG signals to researchers.
... Digital Press Kit Read the MMWR Science Clips ADHD in Young Children Use recommended treatment first Language: ... The recommended first treatment for young children with ADHD is underused. The American Academy of Pediatrics recommends ...
Young people in adult education
Directory of Open Access Journals (Sweden)
Albert Mrgole
1997-01-01
Full Text Available The increasing number of young people participating in adult education programmes has, in the recent years, raised the question of transfer from regular education system to labour market where a large proportion of young people remain socially marginalized and isolated. Young people in adult education are a special target group; in order to plan educational programmes properly, we need to be familiar with their specific characteristics. The article, on the level of a statistical data outline and its paradoxes, introduces the category of young people in adult education as an impact of system factors, and defines related problems in the register, which - for more thorough understanding - dictates sociologically and anthropologically directed analytical approach. The first effect of this, not solely pedagogical view, is presented in the second part of the article, where Mrgole proposes an analysis of educational needs definition and its dangerous consequences in original planning of educational programmes. The concluding part takes a wider perspective and treats the factors of early school-leaving of young people, taking into consideration direct experience in experimental educational programmes for the young. The article ends with an outline of basic elements which the planners of andragogical educational programmes intended for young people should consider in their planning to achieve effective curricula.
Individual-Level Predictors of Young Children's Aspirations
Moulton, Vanessa; Flouri, Eirini; Joshi, Heather; Sullivan, Alice
2018-01-01
Often young children already have some ideas about what they want to do in the future. Using data from a large UK cohort study, we investigated the individual determinants of seven-year-old children's aspirations, controlling for parental socio-economic background and parental involvement in learning. At age 7, not all children's aspirations were…
Effects of television exposure on developmental skills among young children.
Lin, Ling-Yi; Cherng, Rong-Ju; Chen, Yung-Jung; Chen, Yi-Jen; Yang, Hei-Mei
2015-02-01
Literature addressing the effects of television exposure on developmental skills of young children less than 36 months of age is scarce. This study explored how much time young children spend viewing television and investigated its effects on cognitive, language, and motor developmental skills. Data were collected from the Pediatric Clinics at University Medical Center in Southern Taiwan. The participants comprised 75 children who were frequently exposed to television and 75 children who were not or infrequently exposed to television between 15 and 35 months old. The age and sex were matched in the two groups. The Bayley Scales of Infant Development-second edition and Peabody Developmental Motor Scales-second edition were used to identify developmental skills. Independent t-tests, χ(2) tests, and logistic regression models were conducted. Among 75 children who were frequently exposed to television, young children watched a daily average of 67.4 min of television before age 2, which was excessive according to the American Academy of Pediatrics. Viewing television increased the risk of delayed cognitive, language, and motor development in children who were frequently exposed to television. Cognitive, language, and motor delays in young children were significantly associated with how much time they spent viewing television. The type of care providers was critical in determining the television-viewing time of children. We recommend that pediatric practitioners explain the impacts of television exposure to parents and caregivers to ensure cognitive, language, and motor development in young children. Advocacy efforts must address the fact that allowing young children to spend excessive time viewing television can be developmentally detrimental. Copyright © 2014 Elsevier Inc. All rights reserved.
Boukhanovsky, Alexander V; Krzhizhanovskaya, Valeria V; Athanassoulis, Gerassimos A; Klimentov, Alexei A; Sloot, Peter M A
2015-01-01
We present an annual international Young Scientists Conference (YSC) on computational science http://ysc.escience.ifmo.ru/, which brings together renowned experts and young researchers working in high-performance computing, data-driven modeling, and simulation of large-scale complex systems. The first YSC event was organized in 2012 by the University of Amsterdam, the Netherlands and ITMO University, Russia with the goal of opening a dialogue on the present and the future of computational science and its applications. We believe that the YSC conferences will strengthen the ties between young scientists in different countries, thus promoting future collaboration. In this paper we briefly introduce the challenges the millennial generation is facing; describe the YSC conference history and topics; and list the keynote speakers and program committee members. This volume of Procedia Computer Science presents selected papers from the 4th International Young Scientists Conference on Computational Science held on 25 ...
[The readiness of the young teacher for the job].
Ruskova, R
1992-01-01
The study aims at studying the professional readiness of the young teachers concerning their psychic state. It includes subjective-individual determinants--attitude to the profession, professional choice and steadiness, professional skills and satisfaction. The investigation is part of a broad complex study. The method used is directed first of all to self-estimation of the teacher concerning the structural system of the pedagogic activity which embraces supplementary questionnaire, revealing the motivation side of the scales for self-estimation. The subject of the examination are teachers from primary schools with length of service one to five years--time for completing their adaptation to the profession. The investigation includes 40 teachers from the cities of Sofia and Burgas. A general conclusion could be made, that there is professional readiness of the young teacher to be up to the requirements. His/her self-estimation corresponds to the adaptive behaviour and the choice of profession has a considerable effect on the professional steadiness. The general low satisfaction is not a sign for dysadaptation, but this low level presupposes lack of stimuli for personal development and perfection.
Socialisation into Organised Sports of Young Adolescents with a Lower Socio-Economic Status
Pot, Niek; Verbeek, Jan; van der Zwan, Joris; van Hilvoorde, Ivo
2016-01-01
Studies investigating sport socialisation often focussed on the barriers for youngsters from lower socio-economic status (SES) families to participate in sport. In the present study, the socialisation into sports of young adolescents from lower SES families that "do" participate in organised sports was investigated. A total of 9 girls…
Irreducible Specht modules are signed Young modules
Hemmer, David J.
2005-01-01
Recently Donkin defined signed Young modules as a simultaneous generalization of Young and twisted Young modules for the symmetric group. We show that in odd characteristic, if a Specht module $S^\\lambda$ is irreducible, then $S^\\lambda$ is a signed Young module. Thus the set of irreducible Specht modules coincides with the set of irreducible signed Young modules. This provides evidence for our conjecture that the signed Young modules are precisely the class of indecomposable self-dual module...
Impact of socioeconomic status on the use of inhaled corticosteroids in young adult asthmatics
DEFF Research Database (Denmark)
Davidsen, Jesper Rømhild; Søndergaard, Jens; Hallas, Jesper
2011-01-01
OBJECTIVE: The aim of this population-based longitudinal study was to examine the associations between socioeconomic status (SES) and anti-asthmatic treatment with inhaled corticosteroids (ICS) among young Danish adult asthmatics, and to investigate whether these associations were consistent over...... use in young adult asthmatics. To encourage ICS use, special attention should be paid to asthmatics with low educational level and low income. Further studies are needed to elucidate underlying mechanisms for this socioeconomic inequality....
An Exploratory Investigation of the Role of Parenting Stress in Relationship Focused Intervention
Alquraini, Turki; Mahoney, Gerald
2015-01-01
Background: Mothers of young children with Pervasive Developmental Disorders (PDD) and other disabilities (DD) have been reported to experience high levels of stress. This investigation examined the effects of parental stress on mother's participation in a Relationship Focused intervention (RFI). Methods: Mothers and young children who had either…
Stumbling over obstacles in older adults compared to young adults
Schillings, AM; Mulder, T; Duysens, J
Falls are a major problem in older adults. Many falls occur because of stumbling. The aim of the present study is to investigate stumbling reactions of older adults and to compare them with young adults. While subjects walked on a treadmill, a rigid obstacle unexpectedly obstructed the forward sway
Exposure to Interparental Conflict and Psychological Disorder among Young Adults
Turner, Heather A.; Kopiec, Kathleen
2006-01-01
This article examines the effect of exposure to interparental conflict on the mental health of young adults. Based on a diverse sample of 649 students from three New England colleges, the authors investigate the association between nonviolent interparental conflict during childhood, subsequent distress and disorder, and identified factors that…
Alternative Education Engaging Indigenous Young People: Flexi Schooling in Queensland
Shay, Marnee; Heck, Deborah
2015-01-01
This article will discuss some of the findings from a qualitative research project that explored the connections between alternative education and Indigenous learners. This study investigated how flexi school leaders reported they were supporting Indigenous young people to remain engaged in education. The results of the survey provide demographic…
The Role of Perceptions in Dating Violence among Young Adolescents
Prospero, Moises
2006-01-01
The high prevalence of dating violence and the severity of its aftermath warrant the collaboration between research and practice for the development of prevention and intervention programs. This study investigates young adolescents' perceptions of dating partner's behaviors in common dating situations and their behavioral reaction to these dating…
Clinical characteristics and outcome of intracerebral hemorrhage in young adults
Rutten-Jacobs, L.C.A.; Maaijwee, N.A.M.M.; Arntz, R.M.; Schoonderwaldt, H.C.; Dorresteijn, L.D.A.; Dijk, E.J. van; Leeuw, F.E. de
2014-01-01
Data on determinants of prognosis after intracerebral hemorrhage (ICH) in young adults are scarce. Our aim was to identify clinical determinants of prognosis after ICH in adults aged 18-50. We investigated 98 consecutive patients with an ICH, aged 18-50 years, admitted to our hospital between 1980
Attitude of Young Adults towards New Luxury Brand Positioning in Chinese Coffee Market
Gan, Lu
2011-01-01
The aim of this dissertation is to investigate the perception of young adults – age between 18 and 25 – towards new luxury brand positioning in the coffee market, in order to know how new luxury brand positioning influences young adults and what elements lead them to new luxury brands. Similar phrases to new luxury brand positioning are Masstige positioning and affordable luxury. The wants of luxury products and relatively low price makes the need for this research. This dissertation was base...
Games AS Warming Up Activities In Young Learners' Classrooms At An English Course
Aisyatin, Noviani
2014-01-01
The present research aimed at investigating types of games used by a teacher as warming-up activities in young learners' classrooms. The research involved a teacher of an English course and her young learner students. The data were collected by using observation and interview. The collected data were analyzed by using qualitative method. According to the result of data collection and data analysis, it was found that the teacher applied some types of games proposed by Hadfield (2001) and Evans...
Sustainable healthy eating behaviour of young adults: towards a novel methodological approach
Directory of Open Access Journals (Sweden)
Zuzanna Pieniak
2016-07-01
Full Text Available Abstract Background Food, nutrition and health policy makers are poised with two pertinent issues more than any other: obesity and climate change. Consumer research has focused primarily on specific areas of sustainable food, such as organic food, local or traditional food, meat substitution and/or reduction. More holistic view of sustainable healthy eating behaviour has received less attention, albeit that more research is emerging in this area. Methods/design This study protocol that aims to investigate young consumers’ attitudes and behaviour towards sustainable and healthy eating by applying a multidisciplinary approach, taking into account economical, marketing, public health and environmental related issues. In order to achieve this goal, consumers’ reactions on interactive tailored informational messages about sustainable from social, environmental and economical point of view, as well as healthy eating behaviour in a group of young adults will be investigated using randomized controlled trial. To undertake the objective, the empirical research is divided into three studies: 1 Qualitative longitudinal research to explore openness to adopting sustainable healthy eating behaviour; 2 Qualitative research with the objective to develop a sustainable healthy eating behaviour index; and 3 Randomised controlled trial to describe consumers’ reactions on interactive tailored messages about sustainable healthy eating in young consumers. Discussion To our knowledge, this is the first randomised controlled trial to test the young adults reactions to interactive tailor made messages on sustainable healthy eating using mobile smartphone app. Mobile applications designed to deliver intervention offer new possibilities to influence young adults behaviour in relation to diet and sustainability. Therefore, the study will provide valuable insights into drivers of change towards more environmentally sustainable and healthy eating behaviours. Trial
TEACHER’S PERCEPTION OF TEACHING WRITING TO YOUNG LEARNERS USING STORY
Directory of Open Access Journals (Sweden)
Iin Inawati
2016-09-01
Full Text Available This study aims to explore the teacher’s perception of teaching writing to young learners using story and to investigate her practice of teaching writing in primary school context. This study utilized a case study research design in which an English teacher became the participant. The data were obtained from interview and documents analysis. Analysis of data showed that the teacher neglect to use story in her writing class because of her perception that story is difficult to be used in teaching writing for young learners. The second finding showed that the teacher had provided various activities in writing development in which the students should use their thinking skill, such as: drawing a school map and writing based on the picture they draw, or open response to a picture.Keywords: writing, young learners, meaningful language, story
Reliability of anthropometric measurements in young male and female artistic gymnasts.
Siatras, Theophanis; Skaperda, Malamati; Mameletzi, Dimitra
2010-12-01
Body dimensions and body composition of children participating in artistic activities, such as gymnastics and many types of dancing, are important factors in performance improvement. The present study aimed to determine the reliability of a series of selected anthropometric measurements in young male and female gymnasts. Segment lengths, body breadths, circumferences, and skinfold thickness were measured in 20 young gymnasts by the same experienced examiner, using portable and easy-to-use instruments. All parameters were measured twice (test-retest) under the same conditions within a week's period. The high intra-class correlation coefficient (ICC) values ranging from 0.87 to 0.99, as well as the low coefficient of variation (CV) values (artistic gymnasts. Therefore, these measurements could contribute to further research in this field of investigation, helping to monitor young artistic gymnasts' growth status and identify specific characteristics for increased performance in this sport.
Vermunt, Lindy C.; Buysse, Corinne M.; Joosten, Koen F.; Duivenvoorden, Hugo J.; Hazelzet, Jan A.; Verhulst, Frank C.; Utens, Elisabeth M.
2011-01-01
To investigate long-term psychosocial outcomes in young adults who survived septic shock caused by Neisseria meningitidis (meningococcal septic shock) during childhood. A cross-sectional study. The psychological investigation took place in the department of Child and Adolescent Psychiatry of the
Vermunt, Lindy C.; Buysse, Corinne M.; Joosten, Koen F.; Duivenvoorden, Hugo J.; Hazelzet, Jan A.; Verhulst, Frank C.; Utens, Elisabeth M.
Objective: To investigate long-term psychosocial outcomes in young adults who survived septic shock caused by Neisseria meningitidis (meningococcal septic shock) during childhood. Design: A cross-sectional study. Setting: The psychological investigation took place in the department of Child and
Rovio, Suvi P; Pahkala, Katja; Nevalainen, Jaakko; Juonala, Markus; Salo, Pia; Kähönen, Mika; Hutri-Kähönen, Nina; Lehtimäki, Terho; Jokinen, Eero; Laitinen, Tomi; Taittonen, Leena; Tossavainen, Päivi; Viikari, Jorma; Rinne, Juha O; Raitakari, Olli T
2016-07-01
Age, education, and sex associate with cognitive performance. We investigated associations between age, sex, education, and cognitive performance in young or middle-aged adults and evaluated data reduction methods to optimally capture cognitive performance in our population-based data. This study is part of the Cardiovascular Risk in Young Finns Study. The 3,596 randomly selected subjects (aged 3-18 years in 1980) have been followed up for 30 years. In 2011, a computer-based cognitive testing battery (the Cambridge Neuropsychological Test Automated Battery [CANTAB]) was used to assess several cognitive domains. Principal component analysis, categorical and standardized classifications were applied to the cognitive data. Among 34- to 49-year-old participants, cognitive performance declined with age, while education associated with better cognitive functions in several cognitive domains. Men had higher performance on all cognitive domains except visual or episodic memory, in which women outperformed men. The results were similar regardless of the data reduction method used. The associations between sex, age, education, and cognitive performance are already apparent in young adulthood or middle age. Principal component analyses, categorical and standardized classifications are useful tools to analyze CANTAB cognitive data. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
Alcohol and Cannabis: Young People Talking about How Parents Respond to Their Use of These Two Drugs
Highet, Gill
2005-01-01
In recent years, there has been increasing concern over rising levels of alcohol and cannabis use among young people. This paper reports findings from a qualitative investigation of young people's cannabis-related beliefs and behaviour. Fifty-nine boys and girls aged 13 to 15 years were interviewed, mostly in self-selected friendship pairs, in six…
Abnormal brain white matter network in young smokers: a graph theory analysis study.
Zhang, Yajuan; Li, Min; Wang, Ruonan; Bi, Yanzhi; Li, Yangding; Yi, Zhang; Liu, Jixin; Yu, Dahua; Yuan, Kai
2018-04-01
Previous diffusion tensor imaging (DTI) studies had investigated the white matter (WM) integrity abnormalities in some specific fiber bundles in smokers. However, little is known about the changes in topological organization of WM structural network in young smokers. In current study, we acquired DTI datasets from 58 male young smokers and 51 matched nonsmokers and constructed the WM networks by the deterministic fiber tracking approach. Graph theoretical analysis was used to compare the topological parameters of WM network (global and nodal) and the inter-regional fractional anisotropy (FA) weighted WM connections between groups. The results demonstrated that both young smokers and nonsmokers had small-world topology in WM network. Further analysis revealed that the young smokers exhibited the abnormal topological organization, i.e., increased network strength, global efficiency, and decreased shortest path length. In addition, the increased nodal efficiency predominately was located in frontal cortex, striatum and anterior cingulate gyrus (ACG) in smokers. Moreover, based on network-based statistic (NBS) approach, the significant increased FA-weighted WM connections were mainly found in the PFC, ACG and supplementary motor area (SMA) regions. Meanwhile, the network parameters were correlated with the nicotine dependence severity (FTND) scores, and the nodal efficiency of orbitofrontal cortex was positive correlation with the cigarette per day (CPD) in young smokers. We revealed the abnormal topological organization of WM network in young smokers, which may improve our understanding of the neural mechanism of young smokers form WM topological organization level.
The Young Male Cigarette and Alcohol Syndrome
Directory of Open Access Journals (Sweden)
Eveline Vincke
2016-02-01
Full Text Available Despite the many health risks of tobacco and alcohol use, high levels of smoking and drinking are being persisted. Moreover, young men engage more in these behaviors as compared to women. As male physical risk-taking behavior gains attractiveness in short-term mating contexts and given that smoking and drinking have considerable physical costs, this study explores the possibility that tobacco and alcohol use is part of a male short-term mating strategy. By means of a between-subjects experiment (N = 239, women’s perceptions of young male smoking and drinking were investigated. The experiment showed that women perceive men who smoke and drink as being more short-term oriented in their sexuality than nonusers. Moreover, both tobacco and (especially alcohol use brought some attractiveness benefits in short-term mating contexts. A follow-up study (N = 171 confirmed that men’s behavior corresponds with women’s perceptions. Overall, these findings show that cigarette and alcohol use can operate as a short-term mating strategy.
Ayton, Jennifer; Hansen, Emily
2016-01-01
Of all births in Australia, 10 % are to young fathers aged less than 24 years. How young fathers experience any breastfeeding and how this is shaped by their social context is poorly understood. Our aim is to increase understanding of the lived experience of young fathers (aged less than 24 years) and to explore the way they speak about breastfeeding in the context of their lives and parenting. This collective case study analysis uses qualitative data from interviews and focus groups with young fathers (aged less than 24 years) and community support staff. The research was undertaken in Tasmania, Australia, March to December 2013. Young fathers in our study had complex social and emotional circumstances that meant breastfeeding was not a high priority despite them valuing the health benefits of breastfeeding for their babies. If supported by peers and their community they appear to have a more positive parenting experience. Breastfeeding although understood by the young fathers in our study as healthy and desirable is not a priority in their lives. Learning to be a parent and support their partners to breastfeed may be more effectively gained through mentoring and father-to-father localized community based support services.
Young Scientist Wetenschapskalender 2018
van Dalen-Oskam, K.H.; van Zundert, Joris J.; Koolen, Corina
2017-01-01
Bijdragen scheurkalender Young Scientist Wetenschapskalender 2018. Karina van Dalen-Oskam, Belangrijk woord: Wat is het belangrijkste woord in de Nederlandse taal? In: Young Scientist Wetenschapskalender 2018, 1 september Corina Koolen, Op naar het boekenbal: Hoe wordt je beroemd als schrijver? In:
Young Children's Computer Skills Development from Kindergarten to Third Grade
Sackes, Mesut; Trundle, Kathy Cabe; Bell, Randy L.
2011-01-01
This investigation explores young children's computer skills development from kindergarten to third grade using the Early Childhood Longitudinal Study-Kindergarten (ECLS-K) dataset. The sample size of the study was 8642 children. Latent growth curve modeling analysis was used as an analytical tool to examine the development of children's computer…
The perception of natural vs. built environments by young children
Briavel Holcomb
1977-01-01
This paper questions the assumption that young children need exposure to natural environments for healthy psychological development. Preliminary investigation of the environmental perceptions of 4-year-olds suggests that the distinction between natural and man-made milieux is insignificant to preschoolers, and that they find both kinds of environments similarly...
Practising Homelessness: A Typology Approach to Young People's Daily Routines
Mallett, Shelley; Rosenthal, Doreen; Myers, Paul; Milburn, Norweeta; Rotheram-Borus, Mary Jane
2004-01-01
In a study exploring the relationship between typology and risk, we investigated the daily routines of a heterogeneous sample of young men and women from two sites who had been homeless for varying periods (N=1289). Cluster analysis yielded four groups--"Partnered", "Socially engaged", "Service connected-harm avoidant", and "Transgressive"--based…
Greek Young Adults with Specific Learning Disabilities Seeking Learning Assessments
Bonti, Eleni; Bampalou, Christina E.; Kouimtzi, Eleni M.; Kyritsis, Zacharias
2018-01-01
The purpose of this study is to investigate the reasons why Greek young adults with Specific Learning Disabilities (SLD) seek learning assessments. The study sample consisted of 106 adults meeting Diagnostic and Statistical Manual of Mental Disorders criteria for SLD. Data were collected through self-report records (clinical interview) of adults…
Directory of Open Access Journals (Sweden)
Taylor Nicholas F
2010-03-01
Full Text Available Abstract Background Muscle strength is important for young people with Down syndrome as they make the transition to adulthood, because their workplace activities typically emphasise physical rather than cognitive skills. Muscle strength is reduced up to 50% in people with Down syndrome compared to their peers without disability. Progressive resistance training improves muscle strength and endurance in people with Down syndrome. However, there is no evidence on whether it has an effect on work task performance or physical activity levels. The aim of this study is to investigate if a student-led community-based progressive resistance training programme can improve these outcomes in adolescents and young adults with Down syndrome. Methods A randomised controlled trial will compare progressive resistance training with a control group undertaking a social programme. Seventy adolescents and young adults with Down syndrome aged 14-22 years and mild to moderate intellectual disability will be randomly allocated to the intervention or control group using a concealed method. The intervention group will complete a 10-week, twice a week, student-led progressive resistance training programme at a local community gymnasium. The student mentors will be undergraduate physiotherapy students. The control group will complete an arts/social programme with a student mentor once a week for 90 minutes also for 10 weeks to control for the social aspect of the intervention. Work task performance (box stacking, pail carry, muscle strength (1 repetition maximum for chest and leg press and physical activity (frequency, duration, intensity over 7-days will be assessed at baseline (Week 0, following the intervention (Week 11, and at 3 months post intervention (Week 24 by an assessor blind to group allocation. Data will be analysed using ANCOVA with baseline measures as covariates. Discussion This paper outlines the study protocol for a randomised controlled trial on the
Self-reference enhances relational memory in young and older adults.
Hou, Mingzhu; Grilli, Matthew D; Glisky, Elizabeth L
2017-11-27
The present study investigated the influence of self-reference on two kinds of relational memory, internal source memory and associative memory, in young and older adults. Participants encoded object-location word pairs using the strategies of imagination and sentence generation, either with reference to themselves or to a famous other (i.e., George Clooney or Oprah Winfrey). Both young and older adults showed memory benefits in the self-reference conditions compared to other-reference conditions on both tests, and the self-referential effects in older adults were not limited by low memory or executive functioning. These results suggest that self-reference can benefit relational memory in older adults relatively independently of basic memory and executive functions.
Specific phobia predicts psychopathology in young women
Trumpf, Julia; Margraf, Jürgen; Vriends, Noortje; Meyer, Andrea Hans; Becker, Eni S.
2010-01-01
Background Although specific phobia is characterized by an early age at onset and by high rates of comorbidity, few studies have examined comorbid relationships prospectively. Objectives The present study investigated the association between specific phobia and the risk of a broad range of psychopathology among young women in the community. Method Data came from the Dresden Predictor Study in which 1,538 German women (18?25?years) completed a diagnostic interview at two time points. Results W...
Huang, Xiaohu
2013-01-01
Understanding and measuring the size-dependent surface strain of nanowires are essential to their applications in various emerging devices. Here, we report on the diameter-dependent surface strain and Young\\'s modulus of single-crystalline Co nanowires investigated by in situ X-ray diffraction measurements. Diameter-dependent initial longitudinal elongation of the nanowires is observed and ascribed to the anisotropic surface stress due to the Poisson effect, which serves as the basis for mechanical measurements. As the nanowire diameter decreases, a transition from the "smaller is softer" regime to the "smaller is tougher" regime is observed in the Young\\'s modulus of the nanowires, which is attributed to the competition between the elongation softening and the surface stiffening effects. Our work demonstrates a new nondestructive method capable of measuring the initial surface strain and estimating the Young\\'s modulus of single crystalline nanowires, and provides new insights on the size effect. © 2013 The Royal Society of Chemistry.
Young ischemic stroke in Tunisia: a multicentric study.
Kefi, Asma; Larbi, Thara; Abdallah, Meya; Ouni, Amira El; Bougacha, Neil; Bouslama, Kamel; Hamzaoui, Saloua; M'rad, Skander
2017-04-01
There is wanting data regarding young ischemic stroke in developing countries, especially in Tunisia. The purpose of this study was to investigate risk factors and etiologies of young ischemic stroke in Tunisian and make a comparison with previous reports. A total of 102 young ischemic stroke patients (15-45 years old) were admitted, between January 1996 and August 2007, to 11 departments of internal medicine in different Tunisian hospitals. The risk factors for stroke were documented and assessed. Diagnosis workup consisted of anamnesis, complete physical examination and extensive laboratory, radiologic, immunologic, neurologic and cardiologic examination. Stroke etiologies were classified according the Trial of ORG 10172 in acute stroke treatment. There were 42 men (41.2%) and 60 women (58.89%) with a mean age at onset of 35.7 years. As regards stroke subtype, large-artery atherosclerosis was diagnosed in 6.9% of cases, cardioembolism in 11.8%, small-vessel occlusion in 8.8%, other determined etiology in 37.3% and undetermined etiology in 35.3%. Concerning the traditional risk factors, smoking (31.4%), hypertension and diabetes mellitus (12.7% for each one) and a family history of stroke (10.8%) were the most common. The mean follow-up period was 30.5 months. In our study, traditional risk factors were not-so-uncommon in young adults with ischemic stroke suggesting that prevention can go through controlling these factors. Stroke of other determined etiology was the most common among our patients, so that a broad and detailed diagnostic workup is crucial to puzzle out the etiology for more and better stroke prevention.
DEFF Research Database (Denmark)
Gustavsen, S; Søndergaard, Helle Bach; Oturai, D B
2016-01-01
and found that shift work at young age is associated with an increased risk of developing MS. In this study we focused on the effect of shift work in the vulnerable period between 15-19 years. OBJECTIVE: The aim of this study was to investigate the association between shift work at young age and the risk...
Evang, Are; Øverlien, Carolina
2015-01-01
The aim of this article is to investigate the competence of young children staying with their mothers in refuges for abused women as participants in qualitative interviews. Discourse of the verbal and non-verbal actions of seven young children (4-7 years old) was analysed using a theory originally developed to describe infant-mother interaction as…
2004-01-01
In view of 50th anniversary of CERN, about 20 young artists will be visiting CERN from 26 to 31 January to learn about the laboratory's research and the mysterious world of particle physics. The impressions they take home will be the main inspiration for the artwork they will then produce for an exhibition to be inaugurated in October 2004 as part of CERN's 50th anniversary celebration. We are looking for scientists who are interested in the Art-Science synergy and who can volunteer to discuss their work at CERN to these young artists during this week (25-31/01). Please contact renilde.vanden.broeck@cern.ch if you are interested. The project is called Young Artists@ CERN and for more information look at this website: http://www.hep.ucl.ac.uk/~andy/CERNart/
Chervonsky, Elizabeth; Hunt, Caroline
2018-04-26
Previous research has established that the ability to manage emotions effectively is critical to healthy psychological and social development in adolescents. However, less research has considered the relationships between specific emotion regulation (ER) strategies, such as reappraisal and suppression, and social wellbeing in this age group. The current study investigated the concurrent and longitudinal relationships between 2 ER strategies (reappraisal and suppression) and social outcomes (peer victimization, friendship satisfaction, and family satisfaction) in young adolescents. Analyses also controlled for mental health (anxiety and depression). Given likely gender differences in these variables, key analyses were conducted in parallel for males and females. There were 232 Australian adolescents who completed measures in Grade 7 (Age Mean = 11.97, SD = .35; 64% female) and a year later in Grade 8. Zero-order correlations indicated an inverse relationship between suppression use and social wellbeing variables, although a number of these associations were no longer significant when controlling for mental health. There was limited evidence that reappraisal was uniquely related to social outcomes. However, interaction effects suggested that greater use of reappraisal might have provided some protection against the negative social effects of poorer mental health. Poorer mental and social wellbeing also appeared to be related to ER strategy use, particularly greater suppression use. The findings suggest that ER strategy use, mental health, and social outcomes all play important and interrelated roles in adolescent wellbeing. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
Harassment at work? Empowerment and autonomy as coping strategies of young workers.
Turte, Samantha Lemos; Correa, Maria Eduarda Cavadinha; da Luz, Andrea Aparecida; Fischer, Frida Marina
2012-01-01
There is a considerable number of researches about workplace violence, but few relate young workers and work harassment. This study aimed to investigate the reported perceptions of young apprentices and trainees about moral harassment at work and related coping strategies. Forty adolescent workers (22 men and 18 women) between 15 and 20 years old who received training by a non-governmental organization in São Paulo, Brazil, participated in the study. Data collection included individual and collective interviews. It was used an in-depth semi structured interview protocol. The discourses were analyzed using the hermeneutic-dialectic frame. Results showed that young workers reported little or no knowledge of strategies to cope with moral harassment at work, showing vulnerability to the effects of aggression. Effective coping strategies at work should embrace two important concepts of health promotion: empowerment and autonomy.
Health conditions and their impact among adolescents and young adults with Down syndrome.
Directory of Open Access Journals (Sweden)
Terri J Pikora
Full Text Available OBJECTIVE: To examine the prevalence of medical conditions and use of health services among young adults with Down syndrome and describe the impact of these conditions upon their lives. METHODS: Using questionnaire data collected in 2011 from parents of young adults with Down syndrome we investigated the medical conditions experienced by their children in the previous 12 months. Univariate, linear and logistic regression analyses were performed. RESULTS: We found that in addition to the conditions commonly experienced by children with Down syndrome, including eye and vision problems (affecting 73%, ear and hearing problems (affecting 45%, cardiac (affecting 25% and respiratory problems (affecting 36%, conditions also found to be prevalent within our young adult cohort included musculoskeletal conditions (affecting 61%, body weight (affecting 57%, skin (affecting 56% and mental health (affecting 32% conditions and among young women menstrual conditions (affecting 58%. Few parents reported that these conditions had no impact, with common impacts related to restrictions in opportunities to participate in employment and community leisure activities for the young people, as well as safety concerns. CONCLUSION: There is the need to monitor, screen and provide appropriate strategies such as through the promotion of healthy lifestyles to prevent the development of comorbidities in young people with Down syndrome and, where present, to reduce their impact.
Pierce, JP; Sargent, JD; Portnoy, DB; White, M; Noble, M; Kealey, S; Borek, N; Carusi, C; Choi, K; Green, VR; Kaufman, AR; Leas, E; Lewis, MJ; Margolis, KA; Messer, K
2018-01-01
© 2018 American Medical Association. All rights reserved. IMPORTANCE Cigarette marketing contributes to initiation of cigarette smoking among young people, which has led to restrictions on use of cigarette advertising. However, little is known about other tobacco advertising and progression to tobacco use in youth and young adults. OBJECTIVE To investigate whether receptivity to tobacco advertising among youth and young adults is associated with progression (being a susceptible never user or ...
Bravo Santos, R; Delgado, J; Cubero, J; Franco, L; Ruiz-Moyano, S; Mesa, M; Rodríguez, A B; Uguz, C; Barriga, C
2016-03-01
The objective of the present study was to compare differences between elderly rats and young obesity-induced rats in their activity/inactivity circadian rhythm. The investigation was motivated by the differences reported previously for the circadian rhythms of both obese and elderly humans (and other animals), and those of healthy, young or mature individuals. Three groups of rats were formed: a young control group which was fed a standard chow for rodents; a young obesity-induced group which was fed a high-fat diet for four months; and an elderly control group with rats aged 2.5 years that was fed a standard chow for rodents. Activity/inactivity data were registered through actimetry using infrared actimeter systems in each cage to detect activity. Data were logged on a computer and chronobiological analysis were performed. The results showed diurnal activity (sleep time), nocturnal activity (awake time), amplitude, acrophase, and interdaily stability to be similar between the young obesity-induced group and the elderly control group, but different in the young control group. We have concluded that obesity leads to a chronodisruption status in the body similar to the circadian rhythm degradation observed in the elderly.
The course of unilateral intracranial arteriopathy in young adults with arterial ischemic stroke.
Bulder, Marcel M M; Braun, Kees P J; Leeuwis, Jan Willem; Lo, Rob T H; van Nieuwenhuizen, Onno; Kappelle, L Jaap; Klijn, Catharina J M
2012-07-01
Unilateral intracranial focal nonprogressive arteriopathy is often found in children with arterial ischemic stroke. We aimed to investigate the course of unilateral intracranial arteriopathy in young adults. We searched the Utrecht Stroke Database for patients between 16 and 50 years of age diagnosed with anterior circulation arterial ischemic stroke and a nonatherosclerotic, unilateral intracranial large-artery arteriopathy between 1991 and 2005. We assessed clinical features, potential causes, risk factors, extent of infarction and arteriopathy at presentation, long-term angiographic course, and clinical outcome. Of 356 patients with anterior circulation arterial ischemic stroke, 17 (5%) had a documented unilateral intracranial arteriopathy, of whom 14 could be included for follow-up investigations (median age, 34 years; range, 27-49 years). Median duration of follow-up was 8.8 years (range, 1.7-12.8 years). In 11 patients, onset of symptoms was not abrupt. The arteriopathy normalized completely in 5 and improved in 3 patients; in none of the patients did the arteriopathy worsen. Two of 14 patients had recurrent symptoms. Ten patients (71%) had a good outcome (modified Rankin Scale score≤2). In young adults, arterial ischemic stroke is rarely caused by a unilateral intracranial arteriopathy. Similar to children, onset of symptoms in young adults is often not abrupt and the arteriopathy may improve over time. Late recurrences were rare. Possibly, a monophasic inflammatory process, as has been suggested for childhood intracranial focal nonprogressive arteriopathies, also occurs in young adults.
The Development of Young Children's Understanding of the Process of Evaporation.
Beveridge, Michael
1985-01-01
This investigation of the development of young children's concept of evaporation examines their intuitive explanations of real world events involving evaporation. A study of the effects of providing evidence contradicting their explanations and of directing their attention to relevant situational features provides insight into the development of…
Bounded Rationality and Satisficing in Young People's Web-Based Decision Making.
Agosto, Denise E.
2002-01-01
Investigated behavioral decision-making theories of bounded rationality and satisficing in relation to young people's decision making in the World Wide Web and considered the role of personal preferences. Results of this study of ninth- and tenth-grade females consider time constraints, information overload, physical constraints, reduction…
Welfare reforms and the cognitive development of young children.
Williamson, Deanna L; Salkie, Fiona J; Letourneau, Nicole
2005-01-01
To investigate whether the cognitive development of young children in poverty is affected by activities of their primary caregiver and by household income source, which are two components of family poverty experience that have been affected by recent welfare reforms. Bivariate and multivariate analyses were used to examine the relationships that caregiver activity, household income source, and family characteristics (family income adequacy, caregiver depressive symptoms, caregiver education) have with the cognitive development of 59 impoverished children less than three years old. Of the three poverty experience variables included in the multivariate analysis, only employment as the exclusive source of household income had an independent relationship (positive) with children's cognitive development. Two of the family characteristics, income adequacy and caregiver education, also were associated with the children's cognitive score, and they were both better relative predictors than the employment-only income source variable. Income adequacy was positively associated and caregiver education was negatively associated with children's cognitive development. Although recent welfare reforms, in combination with economic growth and declining unemployment, have changed the poverty experience of young families by increasing the proportion that secure at least part of their income from employment, our study provides preliminary evidence that these reforms have made little difference for most young impoverished children. Instead, our findings suggest that the cognitive development of young children is influenced as much by the actual amount of household income as by their parents' activity and source of income.
A bidirectional association between cognitive ability in young adulthood and epilepsy
DEFF Research Database (Denmark)
Osler, Merete; Mortensen, Erik L; Christensen, Kaare
2018-01-01
Aim: To investigate the bidirectional association between cognitive ability in young adulthood and epilepsy. Methods: This cohort study included 1 159 076 men enrolled in the mandatory conscription board examination from the Danish Conscription Database (DCD; 658 465 men examined 1957-84), the Da......Aim: To investigate the bidirectional association between cognitive ability in young adulthood and epilepsy. Methods: This cohort study included 1 159 076 men enrolled in the mandatory conscription board examination from the Danish Conscription Database (DCD; 658 465 men examined 1957...... with epilepsy before conscription, and they had about 0.25 standard deviation (SD) lower cognitive scores than men without epilepsy. The largest difference in cognition was seen for those with the largest number of hospital contacts. A total of 22 364 (1.9%) men developed epilepsy, and cognitive ability......: The cognitive impairment seen in adults with epilepsy seems to reflect combined effects of epileptic processes and lower premorbid cognitive ability....
Ramsey, Rachelle R; Holbein, Christina E; Powers, Scott W; Hershey, Andrew D; Kabbouche, Marielle A; O'Brien, Hope L; Kacperski, Joanne; Shepard, Jeffrey; Hommel, Kevin A
2018-01-01
Background Effective management of migraine requires adherence to treatment recommendations; however, adolescents with migraine take their daily medications only 75% of the time. Low-cost adherence-focused interventions using technology may improve adherence, but have not been investigated. Methods Thirty-five adolescents and young adults (13-21 years) with migraine participated in an AB-design pilot study to assess the use of a mobile phone adherence-promotion application ("app") and progressive reminder system. Adherence was calculated using electronic monitoring during the baseline period and medication adherence intervention. Results Relative to baseline, adherence significantly improved during the first month of the intervention. Specifically, improvements existed for older participants with lower baseline adherence. Self-reported app-based adherence rates were significantly lower than electronically monitored adherence rates. Participants rated the intervention as acceptable and easy to use. Conclusions "Apps" have the potential to improve medication adherence and are a promising intervention for adolescents and young adults with low adherence. Involving parents in the intervention is also helpful. Providers should assess barriers to adherence and use of technology-based interventions, encourage parents to incorporate behavioral incentives, and provide referrals for more intensive interventions to improve long-term outcomes. Further, tracking adherence in an app may result in an underestimation of adherence. Future full-scale studies should be conducted to examine adherence promotion app interventions.
Handgrip force steadiness in young and older adults
DEFF Research Database (Denmark)
Blomkvist, Andreas W; Eika, Fredrik; de Bruin, Eling D
2018-01-01
) was investigated in a test-retest design with seven days between sessions. Ten young and thirty older adults were recruited and handgrip steadiness was tested at 5%, 10% and 25% of maximum voluntary contraction (MVC) using Nintendo Wii Balance Board (WBB). Coefficients of variation were calculated from the mean...... force produced (CVM) and the target force (CVT). Area between the force curve and the target force line (Area) was also calculated. For the older adults we explored reliability using intraclass correlation coefficient (ICC) and agreement using standard error of measurement (SEM), limits of agreement......, CVT and Area was 0.815, 0.806 and 0.464, respectively. Averaged ICC on 5%, 10%, and 25% of MVC was 0.751, 0.667 and 0.668, respectively. Measures of agreement showed similar trends with better results for CVM and CVT than for Area. Young adults had better handgrip steadiness than older adults across...
Self-esteem Among Young Bisexual Women in Norway
DEFF Research Database (Denmark)
Buer, Liliana; Anderssen, Norman; Malterud, Kirsti
2017-01-01
The aim of this study was to investigate the relationships between self-esteem, perception of social acceptance and feeling of loneliness in a sample of young bisexual, lesbian and heterosexual women, including assessing self-esteem longitudinally across 13 years. The analyses were based on self......-completed questionnaires from the longitudinal study “Young in Norway” (13 years follow-up, 1992-2005). N=1,598 female participants at baseline and follow-up (45 bisexual women, 21 lesbian women, 1,532 heterosexual women), age 25-32 years at follow-up. At baseline, there were no differences in self-esteem, but at follow......-up bisexual women reported lower self-esteem, lower levels of perceived acceptance, and higher levels of loneliness. For bisexual women, self-esteem did not increase from adolescence to adulthood. At follow-up, loneliness had a stronger connection with self-esteem among bisexual women compared to lesbian...
Flavored e-cigarette use: Characterizing youth, young adult, and adult users.
Harrell, M B; Weaver, S R; Loukas, A; Creamer, M; Marti, C N; Jackson, C D; Heath, J W; Nayak, P; Perry, C L; Pechacek, T F; Eriksen, M P
2017-03-01
The purpose of this study is to investigate how the use of flavored e-cigarettes varies between youth (12-17 years old), young adults (18-29 years old), and older adults (30 + years old). Cross-sectional surveys of school-going youth ( n = 3907) and young adult college students ( n = 5482) in Texas, and young adults and older adults ( n = 6051) nationwide were administered in 2014-2015. Proportions and 95% confidence intervals were used to describe the percentage of e-cigarette use at initiation and in the past 30 days that was flavored, among current e-cigarette users. Chi-square tests were applied to examine differences by combustible tobacco product use and demographic factors. Most e-cigarette users said their first and "usual" e-cigarettes were flavored. At initiation, the majority of Texas school-going youth (98%), Texas young adult college students (95%), and young adults (71.2%) nationwide said their first e-cigarettes were flavored to taste like something other than tobacco, compared to 44.1% of older adults nationwide. Fruit and candy flavors predominated for all groups; and, for youth, flavors were an especially salient reason to use e-cigarettes. Among adults, the use of tobacco flavor at initiation was common among dual users (e-cigarettes + combustible tobacco), while other flavors were more common among former cigarette smokers (P = 0.03). Restricting the range of e-cigarette flavors (e.g., eliminating sweet flavors, like fruit and candy) may benefit youth and young adult prevention efforts. However, it is unclear what impact this change would have on adult smoking cessation.
Flavored e-cigarette use: Characterizing youth, young adult, and adult users
Directory of Open Access Journals (Sweden)
M.B. Harrell
2017-03-01
Full Text Available The purpose of this study is to investigate how the use of flavored e-cigarettes varies between youth (12–17 years old, young adults (18–29 years old, and older adults (30+ years old. Cross-sectional surveys of school-going youth (n = 3907 and young adult college students (n = 5482 in Texas, and young adults and older adults (n = 6051 nationwide were administered in 2014–2015. Proportions and 95% confidence intervals were used to describe the percentage of e-cigarette use at initiation and in the past 30 days that was flavored, among current e-cigarette users. Chi-square tests were applied to examine differences by combustible tobacco product use and demographic factors. Most e-cigarette users said their first and “usual” e-cigarettes were flavored. At initiation, the majority of Texas school-going youth (98%, Texas young adult college students (95%, and young adults (71.2% nationwide said their first e-cigarettes were flavored to taste like something other than tobacco, compared to 44.1% of older adults nationwide. Fruit and candy flavors predominated for all groups; and, for youth, flavors were an especially salient reason to use e-cigarettes. Among adults, the use of tobacco flavor at initiation was common among dual users (e-cigarettes + combustible tobacco, while other flavors were more common among former cigarette smokers (P = 0.03. Restricting the range of e-cigarette flavors (e.g., eliminating sweet flavors, like fruit and candy may benefit youth and young adult prevention efforts. However, it is unclear what impact this change would have on adult smoking cessation.
Retention of young female post-doc physics researchers in the UK
Whitelegg, Elizabeth
2004-03-01
The talk will describe the results of a research project to investigate the problems young women physics researchers encountered during early stages of their careers and their perceptions of the longer-term difficulties they anticipated were they to pursue a career in physics research. The project examined quantitative data from a large sample of female members of the UK Institute of Physics (IOP) and qualitative data from intensive interviews with 27 young female doctoral and post-doctoral researchers at an early stage in their careers. In the survey of women PhD members of the IOP, only 15% of the younger women (aged under 30) said they had encountered gender barriers compared with 45% of older women. However, within a few years of completing their PhDs only 25% of the young women remained in physics research although they had previously aspired to work in this area. The reasons given for leaving physics included a dislike of the male culture or atmosphere in research labs, the fact that few of the young women thought that they would ever attain a senior physics post, concerns about balancing a research career with raising a young family and anticipating a need to relocate to match a partners career moves. These are clearly gender-related barriers and constraints although these young women often did not perceive them in this way. This research examines the notion of direct and indirect gender barriers. It addresses the idea of subtle discrimination by examining both institutional employment practices and the prevalent male culture or atmosphere in physics research, which contribute to the leaky pipeline in womens physics employment in the UK.
Çelik, Halil Coskun
2015-01-01
The purpose of this study is to investigate the effects of computer courses on young individuals' computer self-efficacy, attitudes and achievement. The study group of this research included 60 unemployed young individuals (18-25 ages) in total; 30 in the experimental group and 30 in the control group. An experimental research model with pretest…
DEFF Research Database (Denmark)
Vittadini, Nicoletta; Carlo, Simone; Gilje, Øystein
2012-01-01
One of the most significant challenges in researching the social aspects of contemporary societies is to adapt the methodological approach to complex digital media environments. Learning processes take place in this complex environment, and they include formal and informal experiences (learning...... in school, home, and real-virtual communities), peer cultures and intergenerational connections, production and creation as relevant activities, and personal interests as a focal point. Methods used in the study of learning and the social practices of young people must take into account four key issues......: boundaries between online and offline experiences are blurring; young people act performatively; young people act knowingly or reflexively; and the activities of young people cannot be understood through the use of a single method but require the use of multiple tools of investigation. The article discusses...
Counsell, Shelly L.; Wright, Brian L.
2016-01-01
Physical science activities provide multiple and varied opportunities for young children to actively observe, engage in, interact with, and interpret experiences in the physical world within diverse, inclusive settings. If all learners are to gain access to, fully participate in, and achieve maximum profit from early science opportunities,…
Effectiveness of individual placement and support supported employment for young adults.
Bond, Gary R; Drake, Robert E; Campbell, Kikuko
2016-08-01
The individual placement and support (IPS) model of supported employment was first developed in community mental health centres for adults with severe mental illness. While IPS is an established evidence-based practice in this broad population, evidence on its effectiveness focused specifically on young adults has been limited. The current study aimed to address this gap. To investigate the effects of IPS on young adults, the authors conducted a secondary analysis on a pooled sample of 109 unemployed young adults (under age 30) from four randomized controlled trials employing a common research protocol that included a standardized measurement battery and rigorous fidelity monitoring. Researchers assessed these participants over 18 months on nine competitive employment outcome measures. On all measures, the IPS group had significantly better employment outcomes. Overall, 40 (82%) of IPS participants obtained employment during follow-up compared with 25 (42%) of control participants, χ(2) = 17.9, P < .001. IPS participants averaged 25.0 weeks of employment, compared with 7.0 weeks for control participants, t = 4.50, P < .001. The current analysis supports a small number of previous studies in showing that IPS is highly effective in helping young adults with severe mental illness to attain competitive employment. When young adults acquire competitive jobs and initiate a path towards normal adult roles, they may avoid the cycle of disability and psychiatric patient roles that are demeaning and demoralizing. © 2014 Wiley Publishing Asia Pty Ltd.
Differences in foot kinematics between young and older adults during walking.
Arnold, John B; Mackintosh, Shylie; Jones, Sara; Thewlis, Dominic
2014-02-01
Our understanding of age-related changes to foot function during walking has mainly been based on plantar pressure measurements, with little information on differences in foot kinematics between young and older adults. The purpose of this study was to investigate the differences in foot kinematics between young and older adults during walking using a multi-segment foot model. Joint kinematics of the foot and ankle for 20 young (mean age 23.2 years, standard deviation (SD) 3.0) and 20 older adults (mean age 73.2 years, SD 5.1) were quantified during walking with a 12 camera Vicon motion analysis system using a five segment kinematic model. Differences in kinematics were compared between older adults and young adults (preferred and slow walking speeds) using Student's t-tests or if indicated, Mann-Whitney U tests. Effect sizes (Cohen's d) for the differences were also computed. The older adults had a less plantarflexed calcaneus at toe-off (-9.6° vs. -16.1°, d = 1.0, p = range of motion (ROM) of the midfoot (11.9° vs. 14.8°, d = 1.3, p = young adults. Walking speed did not influence these differences, as they remained present when groups walked at comparable speeds. The findings of this study indicate that independent of walking speed, older adults exhibit significant differences in foot kinematics compared to younger adults, characterised by less propulsion and reduced mobility of multiple foot segments. Copyright © 2013 Elsevier B.V. All rights reserved.
Directory of Open Access Journals (Sweden)
Lavinia DOVLEAC
2015-06-01
Full Text Available This paper aims the investigation of the relationship between entrepreneurial phenomenon among young people in Romania and the business environment, strongly marked by innovation and new technologies, as pillars of sustainable development in the knowledge-based society. For achieving the paper’s goal there are used the results of a qualitative research based on in-depth interview which aim to identify the views and experiences of young entrepreneurs on the advantages and disadvantages of starting an innovative business in Romania. Data analysis allowed the formulation of some recommendations to state institutions, business environment and the academic community to support young entrepreneurs in developing their business right after the launch. Access to new funding sources, guidance and informational support are the principal needs for entrepreneurs in their struggle to develop innovative sustainable businesses. The strong promotion of young entrepreneurs inside their community or at national level contributes to the development of a strong entrepreneurial culture for Romania.
Self-Injury, Help-Seeking, and the Internet: Informing Online Service Provision for Young People.
Frost, Mareka; Casey, Leanne; Rando, Natalie
2016-01-01
Although increasing numbers of young people are seeking help online for self-injury, relatively little is known about their online help-seeking preferences. To investigate the perspectives of young people who self-injure regarding online services, with the aim of informing online service delivery. A mixed-methods exploratory analysis regarding the perspectives of a subsample of young people who reported a history of self-injury and responded to questions regarding preferences for future online help-seeking (N = 457). The sample was identified as part of a larger study (N = 1,463) exploring self-injury and help-seeking. Seven themes emerged in relation to preferences for future online help-seeking: information, guidance, reduced isolation, online culture, facilitation of help-seeking, access, and privacy. Direct contact with a professional via instant messaging was the most highly endorsed form of online support. Young people expressed clear preferences regarding online services for self-injury, supporting the importance of consumer consultation in development of online services.
NanoBiosensing Principles, Development and Application
Ju, Huangxian; Wang, Joseph
2011-01-01
This book will cover the full scope of nanobiosensing, which combines the newest research results in the cross-disciplines of chemistry, biology, and materials science with biosensing and bioanalysis to develop novel detection principles, sensing mechanisms, and device engineering methods. It not only covers the important types of nanomaterials for biosensing applications, including carbon nanotubes, carbon nanofiber, quantum dots, fullerenes, fluorescent and biological molecules, etc., but also illustrates a wide range of sensing principles, including electrochemical detection, fluorescence, chemiluminesence, antibody-antigen interactions, and magnetic detection. The book details novel developments in the methodology and devices of biosensing and bioanalysis combined with nanoscience and nanotechnology, as well as their applications in biomedicine and environmental monitoring. Furthermore, the reported works on the application and biofunction of nanoparticles have attracted extensive attention and interest, ...
PROSFEKTIF METODE SAMPEL DARAH KERING DALAM BIOANALISIS
Directory of Open Access Journals (Sweden)
Supandi Supandi
2017-08-01
Full Text Available Biosampling of dried blood spot method became lately very interested in bioanalysis, some of the advantages given in this method compared to conventional venous canulla (venipuncture; less invasive making it more pleasant for the patient or subject, requires small volume, requires simple transportation process and storage did not need special equipment, suod stabilizes analit and reduces risk of infection. The method of dried blood spot is done by invasive light on the finger or heel prick and then spike on filter paper and dried at room temperature or under nitrogen flow with controlled humidity and stored in bag with desiccant packages, than it analyzed using validation bioanalyzing method. Dried blood spot method can be applied on bioanalysis test for pharmacokinetic, toksikokinetic , epidemiologic and Teurapeutic drug monitoring.
Health-related quality of life of young women with breast cancer. Review of the literature.
Yfantis, Aris; Intas, George; Tolia, Maria; Nikolaou, Michail; Tsoukalas, Nikolaos; Lymperi, Maria; Kyrgias, George; Zografos, George; Kontos, Michalis
2018-01-01
The purpose of the present article was to investigate the health related quality of life (QoL) of young women with breast cancer. For the purposes of this article, we reviewed the literature via the electronic databases Pubmed, Scopus and Google Scholar. Key words used were breast cancer, young women, health related quality of life, and quality of life. Young women reported fatigue, pain in the breast and hand problems with lymphedema as the most frequent physical effects of treatment. Other physical problems were the not periodic and painful menses, vaginal dryness and loss of libido. Many young women had depressive symptoms such as depressed mood, helplessness, hopelessness, sleep loss, psychomotor retardation and disorders of appetite. There were often concerns about the health monitoring and self-image, while they were anxious if they will have a baby in the future or if they can nurture the existing ones. Many problems arose in the career of young women. They faced discrimination in the labor supply and/or layoff because they were considered unable to do their job effectively. In addition, they reported isolation problems and feeling different from other women of similar age. Young women consider that their healthrelated QoL is worse compared with older women. Young women worry about their future, with particular reference to their role as mothers and especially to children-bearing. The free screening and non-exclusion of young women is particularly important for breast cancer prevention and women's well-being.
Examining Writing Performance and Self-Perception for Low Socioeconomic Young Adolescents
Barone, Toni-Ann; Sinatra, Richard; Eschenauer, Robert; Brasco, Robert
2014-01-01
The present case study investigated the impact of a short-term summer literacy approach on writing performance and self-perception of writing for young adolescents of low-income families residing in urban housing projects. The approach offered intensive literacy engagement to offset summer achievement loss; assisted ethnic-minority, low…
78 FR 32116 - TRICARE Young Adult
2013-05-29
...-HA-0029] TRICARE Young Adult AGENCY: Office of the Secretary, DoD. ACTION: Final rule. SUMMARY: This... 2011 (NDAA for FY11). It establishes the TRICARE Young Adult (TYA) program to provide an extended... TRICARE Program coverage made available for purchase worldwide. TYA is similar to young adult coverage...
Selected Films for Young Adults, 1984.
Top of the News, 1984
1984-01-01
This 22-item filmography of 16mm films recommended for use in programs planned for young adults was compiled by the Selected Films for Young Adults Committee, Young Adult Services Division, American Library Association. Producers, directors, distributors, length, price, and brief annotations are provided. Addresses for 12 distributors are…
ROMANIAN YOUNG ENTREPRENEURS FEATURES: AN EMPIRICAL SURVEY
Directory of Open Access Journals (Sweden)
Ceptureanu Sebastian Ion
2015-07-01
Full Text Available There are many studies linking entrepreneurship and economic development. For specialists and public decision makers, developing entrepreneurship seems to be an easy policy action, even though actions and results are rather debatable. Unfortunately the relevant literature is not so generous concerning youth entrepreneurship. Youth is one of the most vulnerable groups in society, especially in the current economic and demographic situation in European Union and worldwide. At the same time, youth is the period when most people engage in their first job, are gaining financial independence and are assuming new responsibilities and roles shaping their identity. With respect to this, starting their own business is a natural choice for many young people. When considering entrepreneurial potential of young Romanians, there is almost not any data available. This paper aims to disseminate the results of a survey focused on young entrepreneurs, designed to fill the gap in the literature about Romanian young entrepreneurs’ features. The empirical study was divided in five parts: A. Personality of young entrepreneurs, highlighting the main features of behaviour and personality of young entrepreneurs. B. Professional background, focusing on young entrepreneurs’ background and how it influences their interest and performance improvement. C. Risk and crisis acceptance, highlighting the ability of young entrepreneurs to deal with critical situations. D. Business and business environment, focusing on internal and environmental aspects of the business. E. Social - cultural attitude, highlighting the attitude of society (incentives and disincentives to entrepreneurial initiatives of young people. This are excerpts of results from the first part, regarding personality of Romanian young entrepreneurs, concerning issues like level of independence, capacity for innovation, self-confidence, decision making process, level of persistence flexibility of young
A DRIED BLOOD SPOT METHOD TO EVALUATE CHOLINESTERASE ACTIVITY IN YOUNG CHILDREN
Field methods are needed to detect and monitor anticholinesterase pesticide exposure of young children. Twenty children, aged 11-18 months, living in an agricultural community along the US/Mexico border were enrolled in a pilot study investigating methods to detect pesticide expo...
HPA axis hyperactivity and attempted suicide in young adult mood disorder inpatients.
Jokinen, Jussi; Nordström, Peter
2009-07-01
Hyperactivity of the Hypothalamic-Pituitary-Adrenal (HPA) axis is a consistent finding in Major Depressive Disorder (MDD) and most prospective studies of HPA-axis function have found that non-suppressors in the dexamethasone suppression test (DST) are more likely to commit suicide during follow-up. The results of studies on HPA-axis function and attempted suicide are less consistent. Suicide attempts are more common among young people than the elderly, whereas suicide is more common among the elderly. The impact of age related changes in HPA-axis system activity in relation to suicidal behaviour across the lifecycle may be of importance. The aim of the present study was to investigate the DST results in 36 young adult (30 years or younger) inpatients with mood disorder, with (n=18) and without suicide attempt at the index episode. The DST non-suppressor rate was 25% among young mood disorder inpatients. DST non-suppression was associated with suicide attempt and post-dexamethasone serum cortisol at 11:00 p.m. was significantly higher in suicide attempters compared to non-attempters. The DST non-suppressor rate was 39% in young adult suicide attempters compared with 11% in non-attempters. The results add to previous evidence in support of the role of HPA axis hyperactivity and suicidal behaviour. The present findings motivate to include HPA axis measures in the assessment of depression in young adults.
Directory of Open Access Journals (Sweden)
Abu-Hammad Osama A
2011-08-01
Full Text Available Abstract Narghile smoking by young females is becoming more acceptable than cigarettes in the conservative societies of Arab countries. Lack of social constraints on narghile smoking has resulted in an increased prevalence of narghile smoking among young Arab females and an earlier age of onset of this habit when compared to cigarette smoking. Documented health hazards of narghile smoking including pulmonary, cardiovascular and neoplastic ailments are consequently expected to affect this vulnerable sector of the population together with their offspring. In this commentary, we shed some light on the changing trend of tobacco use among young Arabic women as shown by an increasing number of studies investigating habits of tobacco use in young people.
Bailey, Lin; Griffin, Christine; Shankar, Avi
2015-05-01
This paper investigates young women's alcohol consumption in the United Kingdom within a widespread culture of intoxication in relation to recent debates about postfeminism and contemporary femininity. Young women are faced with an "impossible dilemma," arising from the contradiction between a hedonistic discourse of alcohol consumption and postfeminist discourse around attaining and maintaining the "right" form of hypersexual heterosexual femininity. Drawing on a recent interview study with 24 young white working-class and middle-class women in the South-West of England, we explore how young women inhabit the dilemmas of contemporary femininity in youth drinking cultures, striving to achieve the "right" form of hypersexual femininity and an "optimum" level of drunkenness.
Knowledge attitudes and practices about hepatitis B and C among young healthy males
International Nuclear Information System (INIS)
Alam, M.; Tariq, W.U.Z.
2006-01-01
The purpose of this study was to assess the basic knowledge, attitudes and practices about viral hepatitis B and hepatitis C among young healthy adults. A total of 2038 young healthy adults belonging to central Punjab were included in the study. A closed structured questionnaire was used to assess the knowledge, attitudes and practices of the individuals. A total of 602(30.74%) of respondents knew that hepatitis B and C are viral diseases. Contaminated needles/syringes, blood transfusion and used blades were identified as a mode of transmission of hepatitis B and C viruses by 84.38%, 69.58%, 25.63 individuals. About 80% replied that even if they were found positive for HBsAg and anti-HCV, they would not have further investigations/ treatment. TV was the leading source of information about these diseases. The attitudes and practices regarding exposure to risk factors were significantly poor from knowledge among young adults. A high level of public awareness, especially among the young, is critical to decrease the burden of these diseases in Pakistan in future. (author)
Zulli, C; Federico, A; Gaeta, L; Del Prete, A; Iadevaia, M; Gravina, A G; Romano, M; Loguercio, C
2014-03-01
Alcohol consumption by adolescents and young adults is an issue of significant public concern. Internet-based Social Networking sites, such as Facebook, are potential avenues to reach young people easily. to underline the innovation in proposing surveys to collect health-related information regarding young people alcohol consumption and other substances abuse by using Social Networking Websites, particularly Facebook. A questionnaire investigating modalities of alcohol consumption, drinking patterns' risk behaviors and other substances abuse was proposed through a "Facebook event" to young Italian Facebook users aged between 16 and 32. Each Facebook user invited to the event was free to participate, to answer to the questionnaire and to invite his "Facebook friends". During the 89 days of permanence on the Social Network, 1846 Facebook users participated the event and 732 of them decided spontaneously to answer the questionnaire. The frequency of answering was 8.2 people per day. About 200 users wrote a positive comment to the initiative on the wall of the event. Sixty% of subjects participating the survey were females. Ninety-one% of people answering the questionnaire were alcohol consumers. More than 50% of alcohol consumers were also smokers. Approximately 50% of subjects were binge drinkers. Illegal drugs were used by the 22.2% of the interviewed people. Facebook resulted an efficient and rapid tool to reach young people from all over Italy and to propose surveys in order to investigate alcohol consumption and alcohol-related health problems in the youth.
The Role of Personality Traits in Young Adult Fruit and Vegetable Consumption.
Conner, Tamlin S; Thompson, Laura M; Knight, Rachel L; Flett, Jayde A M; Richardson, Aimee C; Brookie, Kate L
2017-01-01
This project investigated how individual differences in the big-five personality traits (neuroticism, extraversion, openness to experience, conscientiousness, and agreeableness) predicted plant-food consumption in young adults. A total of 1073 participants from two samples of young adults aged 17-25 reported their daily servings of fruits, vegetables, and two unhealthy foods for comparison purposes using an Internet daily diary for 21 or 13 days (micro-longitudinal, correlational design). Participants also completed the Neuroticism, Extraversion, Openness Five Factor Inventory (NEO-FFI) measure of personality, and demographic covariates including gender, age, ethnicity, and body mass index (BMI). Analyses used hierarchical regression to predict average daily fruit and vegetable consumption as separate dependent variables from the demographic covariates (step 1) and the five personality traits (step 2). Results showed that young adults higher in openness and extraversion, and to some extent conscientiousness, ate more fruits and vegetables than their less open, less extraverted, and less conscientious peers. Neuroticism and agreeableness were unrelated to fruit and vegetable consumption. These associations were unique to eating fruit and vegetables and mostly did not extend to unhealthy foods tested. Young adult women also ate more fruit and vegetables than young adult men. Results suggest that traits associated with greater intellect, curiosity, and social engagement (openness and extraversion), and to a lesser extent, discipline (conscientiousness) are associated with greater plant-food consumption in this population. Findings reinforce the importance of personality in establishing healthy dietary habits in young adulthood that could translate into better health outcomes later in life.
Vestøl, Jon Magne
2016-01-01
Drawing on perspectives from sociocultural theory, this article investigates how Christian denominations are represented in Norwegian textbooks of religious education and by young believers. The main finding is that textbooks and young adherents present religion in substantially different ways. While textbooks relate religion to global and…
Physical health and well-being: Experiences and perspectives of young adult mental health consumers.
McCloughen, Andrea; Foster, Kim; Kerley, David; Delgado, Cynthia; Turnell, Adrienne
2016-08-01
Compromised physical health and raised levels of morbidity and mortality are experienced by young people (16-24 years) with mental illness, and are compounded by psychotropic medication. How this group conceives and experiences physical health is not well understood. We investigated the meanings, beliefs, and endeavours of young people that impact their physical health understandings and behaviours. The present study formed the qualitative phase of a sequential mixed-methods study, and incorporated semistructured interviews with 12 hospitalized young people. Qualitative content analysis was used to analyse data. Participants held a holistic ideal of physical health that they did not meet. Weight change, poor sleep, and limited exercise adversely impacted their lives and self-image. Sedentary behaviour, reduced energy, and limited health literacy compromised effective management of physical health. Young people needed structure and support to assist them in addressing their physical health needs when amotivation overwhelmed their internal resources. Nurses are well placed to help young people increase their competency for health management. Individualized information and methods to promote good physical health are required for this group in jeopardy from physical morbidity and mortality. © 2016 Australian College of Mental Health Nurses Inc.
DEFF Research Database (Denmark)
Hojsak, Iva; Bronsky, Jiri; Campoy, Cristina
2018-01-01
Young child formulae (YCF) are milk-based drinks or plant protein-based formulae intended to partially satisfy the nutritional requirements of young children ages 1 to 3 years. Although widely available on the market, their composition is, however, not strictly regulated and health effects have...... not been systematically studied. Therefore, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Committee on Nutrition (CoN) performed a systematic review of the literature to review the composition of YCF and consider their role in the diet of young children...... for the routine use of YCF in children from 1 to 3 years of life, but they can be used as part of a strategy to increase the intake of iron, vitamin D, and n-3 PUFA and decrease the intake of protein compared with unfortified cow's milk. Follow-on formulae can be used for the same purpose. Other strategies...
International Nuclear Information System (INIS)
Freeman, K.C.
1980-01-01
The young globular clusters of the LMC have ages of 10 7 -10 8 y. Their masses and structure are similar to those of the smaller galactic globular clusters. Their stellar mass functions (in the mass range 6 solar masses to 1.2 solar masses) vary greatly from cluster to cluster, although the clusters are similar in total mass, age, structure and chemical composition. It would be very interesting to know why these clusters are forming now in the LMC and not in the Galaxy. The author considers the 'young globular' or 'blue populous' clusters of the LMC. The ages of these objects are 10 7 to 10 8 y, and their masses are 10 4 to 10 5 solar masses, so they are populous enough to be really useful for studying the evolution of massive stars. The author concentrates on the structure and stellar content of these young clusters. (Auth.)
Evolution for Young Victorians
Lightman, Bernard
2012-01-01
Evolution was a difficult topic to tackle when writing books for the young in the wake of the controversies over Darwin's "Origin of Species." Authors who wrote about evolution for the young experimented with different ways of making the complex concepts of evolutionary theory accessible and less controversial. Many authors depicted presented…
The Contact Principle and Utilitarian Moral Judgments in Young Children
Pellizzoni, Sandra; Siegal, Michael; Surian, Luca
2010-01-01
In three experiments involving 207 preschoolers and 28 adults, we investigated the extent to which young children base moral judgments of actions aimed to protect others on utilitarian principles. When asked to judge the rightness of intervening to hurt one person in order to save five others, the large majority of children aged 3 to 5 years…
Eating behaviours among young women.
Abraham, S F; Mira, M; Beumont, P J; Sowerbutts, T D; Llewellyn-Jones, D
1983-09-03
Disordered eating and weight-control behaviour is becoming increasingly common among adolescent girls. We studied four groups of young women aged between 15 and 27 years (106 school and university students, 50 ballet school students, 22 patients suffering from anorexia nervosa and 44 patients with bulimia). Our results suggest that most young women diet at some time and lose more than three kg in weight; that they may experience episodes of binge eating and "picking" behaviour; and that they wish to be thinner irrespective of their current body weight. Twenty per cent of young women may fulfil the criteria for an eating disorder (bulimia or anorexia nervosa) at some stage, however briefly, and about 7% abuse laxatives or diuretics in order to achieve a fashionably slim figure. We suggest that most young women may pass through a phase of what is currently called disordered eating, and that this is part of normal development and may not necessarily require treatment. The incidence of disordered eating is greater in those young women who are under pressure to maintain a low body weight.
Stroke among young adults at the LAUTECH Teaching Hospital, Osogbo, Nigeria.
Mustapha, A F; Sanya, E O; Bello, T O
2012-01-01
Stroke in young adults is relatively rare and there are very few hospital reports about it in Nigeria. The aetiologic mechanisms of stoke among young adults are quite distinct from those of the adults' populations. The purpose of this retrospective study was to determine the frequency, aetiologic mechanisms and prognosis of stroke among young adults at the LAUTECH Teaching Hospital Osogbo Nigeria. The study was both retrospective and descriptive. Case notes of stroke patients aged 16-45 years managed at the LAUTECH Teaching Hospital Osogbo from June 2005 till February 2008 were retrieved. Demographic data, clinical profile of stroke, laboratory investigation results and treatment outcomes were collated. Clinical diagnosis and classification of stroke was mainly clinical using the WHO clinical criteria. Only 3 patients had cranial CT scan. Out of the total number of 208 stroke patients managed during this period, 27(12.9%) were aged 45 years and below. This comprised of 17 males and 10 females. The age range was between 23-45 years. Using the WHO clinical criteria, there were 14 cases of heamorrhagic CVD and 13 cases of ischaemic CVD. The three cranial CT scan that were done revealed cerebral infarction which was consistent with the clinical diagnosis. Severe hypertension was found in 16 (59.2%) patients on admission. 3 patients had clinical and electrocardiographic evidence of rheumatic heart disease with infective endocarditis. Other risk factors included Sickle cell disease, cardiac arrhythmias etc. 8 out of the 27 patients died giving a percentage mortality of 29.6% and 7 patients were discharged against medical advice. Heamorrhagic stroke was slightly more frequent than ischaemic CVD. Systemic hypertension was also found to be prevalent among these young Nigerian adults with stroke. However, it was difficult to unravel the aetiologic mechanisms of stroke in this study because of paucity of investigations.
Fear appeals in HIV-prevention messages: young people's perceptions in northern Tanzania.
Bastien, Sheri
2011-12-01
The aims of the study were to elicit the perceptions of young people in Tanzania on the role of fear appeals in HIV-prevention messages and to identify important contextual factors that may influence young people's perceptions of HIV-prevention posters. A total of 10 focus groups were conducted to investigate the role of fear appeals using the extended parallel process model (EPPM) as a guide. Young people were shown a series of images (mostly posters) with alternating high and low-threat messages (fear appeals), and then asked questions about their overall beliefs about HIV and AIDS, as well as about their response in terms of perceived susceptibility to HIV infection, the severity of the message, and their perceptions of self-efficacy and response efficacy. The images and messages that specifically targeted young people were highest in inducing perceived susceptibility to HIV infection, while pictorial descriptions of the physical consequences of HIV infection and those messages related to the stigma and discrimination faced by HIV-infected or affected people induced greater perceptions of severity. The information-based posters rated high in inducing response efficacy, while none of the images seemed to convince young people that they had the self-efficacy to perform the recommended health behaviours. The young people expressed a preference for fear-based appeals and a belief that this could work well in HIV-prevention efforts, yet they also stated a desire for more information-based messages about how to protect themselves. Finally, the messages evoking the most emotional responses were those that had been locally conceived rather than ones developed by large-scale donor-funded campaigns. Finding the appropriate balance between fear and efficacy in HIV-prevention messages is imperative. Further research is needed to better understand how and when fear appeals work and do not work in African settings, especially among young people.
Young generation network: facing the future
International Nuclear Information System (INIS)
Berk, R.
1997-01-01
The future of the nuclear industry lies with the young generation. That's why in 1995, ENS supported the creation of the Young Generation Network (YGN). The YGN aims to fulfill the needs and interests of young people working in the nuclear business by organizing special programs with interesting opportunities and activities. (author)
Helping Young People Engage with Scientists
Leggett, Maggie; Sykes, Kathy
2014-01-01
There can be multiple benefits of scientists engaging with young people, including motivation and inspiration for all involved. But there are risks, particularly if scientists do not consider the interests and needs of young people or listen to what they have to say. We argue that "dialogue" between scientists, young people and teachers…
Optical Monitoring of Young Stellar Objects
Kar, Aman; Jang-Condell, Hannah; Kasper, David; Findlay, Joseph; Kobulnicky, Henry A.
2018-06-01
Observing Young Stellar Objects (YSOs) for variability in different wavelengths enables us to understand the evolution and structure of the protoplanetary disks around stars. The stars observed in this project are known YSOs that show variability in the Infrared. Targets were selected from the Spitzer Space Telescope Young Stellar Object Variability (YSOVAR) Program, which monitored star-forming regions in the mid-infrared. The goal of our project is to investigate any correlation between the variability in the infrared versus the optical. Infrared variability of YSOs is associated with the heating of the protoplanetary disk while accretion signatures are observed in the H-alpha region. We used the University of Wyoming’s Red Buttes Observatory to monitor these stars for signs of accretion using an H-alpha narrowband filter and the Johnson-Cousins filter set, over the Summer of 2017. We perform relative photometry and inspect for an image-to-image variation by observing these targets for a period of four months every two to three nights. The study helps us better understand the link between accretion and H-alpha activity and establish a disk-star connection.
Long-Middleton, Ellen R.; Burke, Pamela J.; Lawrence, Cheryl A. Cahill; Blanchard, Lauren B.; Amudala, Naomi H.; Rankin, Sally H.
2012-01-01
Introduction Pregnancy and sexually transmitted infections pose a significant threat to the health and wellbeing of adolescent young women. Abstinence when practiced provides the most effective means in preventing these problems, yet the perspective of abstinent young women is not well understood. The purpose of the investigation was to characterize female adolescents’ motivations for abstinence. Method As part of a larger, cross-sectional quantitative study investigating predictors of HIV risk reduction behaviors, qualitative responses from study participants who never had intercourse were analyzed in a consensus-based process using content analysis and frequency counts. An urban primary care site in a tertiary care center served as the setting, with adolescent young women ages 15–19 years included in the sample. Results Five broad topic categories emerged from the data that characterized motivations for abstinence in this sample: 1) Personal Readiness, 2) Fear, 3) Beliefs and Values, 4) Partner Worthiness and 5) Lack of Opportunity. Discussion A better understanding of the motivations for abstinence may serve to guide the development of interventions to delay intercourse. PMID:22525893
The quest for young eyes. Attention to news among young people in the Low Countries
Van Cauwenberge, Anna
2015-01-01
This dissertation started off with the observation that attention for news among young people decreases. More precisely, previous survey studies outlined a triple shift in the current young generation’s use of news: from more to less news, from offline to online news, and from professional to non-professional news sources. Underlying these three trends, was the finding that news does not constitute a substantial part of the daily routines of young people. This finding is disturbing given news...
Takayasu arteritis in young male
African Journals Online (AJOL)
2012-09-23
Sep 23, 2012 ... The study, diagnosis and treatment of hypertension in the young constitute one of the major ... neck and hypertension. Key words: Hypertension, takayasu arteritis, young adults .... Pregnancy-induced hypertension. Drugs and ...
Valuing the Place of Young People with Learning Disabilities in the Arts
Goddard, Jennifer
2015-01-01
Methodologies of embodied learning, radical pedagogies and applied drama offer a lens through which to investigate the empowerment of young people with learning disabilities in Northern Ireland, thus counteracting more traditional, disempowering methods. According to Helen Nicholson, the "participatory, dialogic and dialectic qualities as…
Text neck and neck pain in 18-21-year-old young adults.
Damasceno, Gerson Moreira; Ferreira, Arthur Sá; Nogueira, Leandro Alberto Calazans; Reis, Felipe José Jandre; Andrade, Igor Caio Santana; Meziat-Filho, Ney
2018-06-01
The aim of this study was to investigate whether there is an association between text neck and neck pain in young adults. Observational cross-sectional study with 150 18-21-year-old young adults from a public high school in the state of Rio de Janeiro was performed. In the self-report questionnaire, the participants answered questions on sociodemographic factors, anthropometric factors, time spent texting or playing on a mobile phone, visual impairments, and concern with the body posture. The neck posture was assessed by participants' self-perception and physiotherapists' judgment during a mobile phone texting message task. The Young Spine Questionnaire was used to evaluate the neck pain. Four multivariate logistic regression models were fitted to investigate the association between neck posture during mobile phone texting and neck pain, considering potential confounding factors. There is no association between neck posture, assessed by self-perception, and neck pain (OR = 1.66, p = 0.29), nor between neck posture, assessed by physiotherapists' judgment, and neck pain (OR = 1.23, p = 0.61). There was also no association between neck posture, assessed by self-perception, and frequency of neck pain (OR = 2.19, p = 0.09), nor between neck posture, assessed by physiotherapists' judgment, and frequency of neck pain (OR = 1.17, p = 0.68). This study did not show an association between text neck and neck pain in 18-21-year-old young adults. The findings challenge the belief that neck posture during mobile phone texting is associated to the growing prevalence of neck pain.
Young drivers and their cars: Safe and sound or the perfect storm?
Oviedo-Trespalacios, Oscar; Scott-Parker, Bridie
2018-01-01
Consistent with the experiences in high-income countries, young drivers remain overrepresented in road trauma statistics in low- and middle-income countries. This article pursues the emerging interest of approaching the young driver problem from a systems thinking perspective in order to design and deliver robust countermeasures. Specifically, the focus of this paper is the cars driven by young drivers. The study of vehicles' characteristics and their interaction with driving behaviour is, more often than not, considered a minor concern when developing countermeasures in young drivers' safety not only in developed nations, but especially in developing nations. Participants completed an online survey containing the 44-item Behaviour of Young Novice Drivers Scale Spanish version (BYNDS-Sp), in addition to providing information regarding their vehicle, any crash involvement, and driving offences. Based on the vehicle model information, the assessment of vehicle safety was conducted for three safety programs (ANCAP, Latin NCAP, U.S. NCAP). Young drivers in Colombia reported a breadth of risky driving behaviours worth targeting in broader interventions. For example, interventions can target speeding, particularly as three quarters of the participants drove small-medium cars associated with poorer road safety outcomes. Moreover, risky driving exposure was highly prevalent amongst the young driver participants, demonstrating the need for them to be driving the safest vehicles possible. It is noteworthy that few cars were able to be assessed by the Latin NCAP (with half of the cars rated having only 0-2 star ratings), and that there was considerable discrepancy between ANCAP, U.S. NCAP, and Latin NCAP ratings. The need for system-wide strategies to increase young driver road safety-such as improved vehicle safety-is vital to improve road safety outcomes in jurisdictions such as Colombia. Such improvements may also require systemic changes such as enhanced vehicle safety
Siriphorn, Akkradate; Chamonchant, Dannaovarat
2015-01-01
[Purpose] The potential health benefits of the Nintendo Wii balance board exercise have been widely investigated. However, no study has been conducted to examine the benefits of Wii exercise for overweight young adults. The aim of this study was to investigate the effect of exercise performed on a Nintendo Wii balance board on the balance and lower limb muscle strength in overweight young adults. [Subjects and Methods] Within-subject repeated measures analysis was used. Sixteen young adults (aged 21.87±1.13 years, body mass index 24.15 ± 0.50 kg/m(2)) were recruited. All subjects performed an exercise program on a Wii balance board for 8 weeks (30 min/session, twice a week for 8 weeks). A NeuroCom Balance Master and a hand-held dynamometer were used to measure balance performance and lower limb muscle strength. [Results] According to the comparison of pre- and post-intervention measurements, the Wii balance board exercise program significantly improved the limit of stability parameters. There was also a significant increase in strength of four lower-limb muscle groups: the hip flexor, knee flexor, ankle dorsiflexor and ankle plantarflexor. [Conclusion] These findings suggest that a Wii balance board exercise program can be used to improve the balance and lower limb muscle strength of overweight young adults.
Effect of the first night shift period on sleep in young nurse students.
Fietze, Ingo; Knoop, Karsten; Glos, Martin; Holzhausen, Martin; Peter, Jan Giso; Penzel, Thomas
2009-12-01
In young hospital nurses being exposed to a night shift work schedule for the first time in their occupational life, sleep quality is investigated quantitatively. A main sleep period and supplementary sleep periods were defined and analyzed to investigate sleep behavior and quality. A total of 30 young nurses (26 women, 4 men), mean age 20.2 +/- 2.1 years participated. A 3 week nursing school period was followed by a 3 week work period with a 3-5 night shift sub-period and recovery days. Sleep-wake behavior was assessed with an actigraph, sleep diaries, Epworth sleepiness scale (ESS), and quality of life was assessed with a standard questionnaire (SF-36). Comparing the school period with the work shift period when excluding recovery days after night shift period significant increase of total sleep time within 24 h was found during the work days (ANOVA P night shift sub-period, there was just a small decline of the main sleep period at day (n.s.) which was not compensated by supplementary sleep episodes. The supplementary sleep during work day varied between 11 min (school period) and 18 min after recovery days from night shift (n.s.). Young healthy nurses tolerate the first night shift exposure very well, according to objective and subjective parameters related to quality of sleep. An increased sleep need during work days lead to longer total sleep time, but do not lead to longer supplementary sleep episodes. Young nurses tolerate the first rotating shift period and the first night shift period very well.
Young women's recent experience of labour and birth care in Queensland.
Redshaw, Maggie; Hennegan, Julie; Miller, Yvette
2014-07-01
young parenthood continues to be an issue of concern in terms of clinical and psychosocial outcomes for mothers and their babies, with higher rates of medical complications such as preterm labour and hypertensive disease and a higher risk of depression. The aim of this study was to investigate how young age impacts on women's experience of intrapartum care. secondary analysis of data collected in a population based survey of women who had recently given birth in Queensland, comparing clinical and interpersonal aspects of the intrapartum maternity care experience for 237 eligible women aged 15-20 years and 6534 aged more than 20 years. Descriptive and multivariate analyses were undertaken. in the univariate analysis a number of variables were significantly associated with clinical aspects of labour and birth and perceptions of care: young women were more likely to birth in a public facility, to travel for birth and to live in less economically advantaged areas, to have a normal vaginal birth and to have one carer through labour. They were also less likely to report being treated with respect and kindness and talked to in a way they could understand. In logistic regression models, after adjustment for parity, other socio-demographic factors and mode of birth, younger mothers were still more likely to birth in a public facility, to travel for birth, to be more critical about interpersonal and aspects of care and the hospital or birth centre environment. this study shows how experience of care during labour and birth is different for young women. Young women reported poorer quality interpersonal care which may well reflect an inferior care experience and stereotyping by health professionals, indicating a need for more effective staff engagement with young women at this time. Copyright © 2013 Elsevier Ltd. All rights reserved.
Parents' and young adults' perspectives on transition outcomes for young adults with autism.
Sosnowy, Collette; Silverman, Chloe; Shattuck, Paul
2018-01-01
Existing research shows that young adults with autism spectrum disorder have poorer outcomes than their peers with other developmental disabilities in the key areas of independent living, postsecondary education, and employment. However, we understand little about how young adults with autism and their families understand and value outcomes and whether these indicators match their goals and aspirations. We interviewed parents (n = 21) and young adults with autism spectrum disorder (n = 20) about their experiences with the transition to adulthood to understand what they consider to be desirable outcomes and how they seek to achieve them. Understanding these perspectives will help identify areas of need as well as disconnections between service objectives and the goals of young adults and their families. Participants described outcomes as more complex and nuanced than current conceptions and measures account for. They defined and evaluated outcomes in relation to their or their child's individual abilities, needs, and desires. These findings provide important insight into challenges to and facilitators of desired outcomes, which has implications for programming, service delivery, and policy.
Thrombophilia testing in young patients with ischemic stroke.
Pahus, Sidse Høst; Hansen, Anette Tarp; Hvas, Anne-Mette
2016-01-01
The possible significance of thrombophilia in ischemic stroke remains controversial. We aimed to study inherited and acquired thrombophilias as risk factors for ischemic stroke, transient ischemic attack (TIA) and amaurosis fugax in young patients. We included patients aged 18 to 50 years with ischemic stroke, TIA or amaurosis fugax referred to thrombophilia investigation at Aarhus University Hospital, Denmark from 1 January 2004 to 31 December 2012 (N=685). Clinical information was obtained from the Danish Stroke Registry and medical records. Thrombophilia investigation results were obtained from the laboratory information system. Absolute thrombophilia prevalences and associated odds ratios (OR) with 95% confidence intervals (95% CI) were reported for ischemic stroke (N=377) and TIA or amaurosis fugax (N=308). Thrombophilia prevalences for the general population were obtained from published data. No strong associations were found between thrombophilia and ischemic stroke, but patients with persistent presence of lupus anticoagulant (3%) had an OR at 2.66 (95% CI 0.84-9.15) for ischemic stroke. A significantly higher risk of TIA/amaurosis fugax was found for factor V Leiden heterozygote (12%) (OR: 1.99 (95% CI 1.14-3.28)). No other inherited or acquired thrombophilia was associated with ischemic stroke, TIA or amaurosis fugax. In young patients, thrombophilia did not infer an increased risk of ischemic stroke. Only factor V Leiden heterozygote patients had an increased risk of TIA/amaurosis fugax, and persistent presence of lupus anticoagulant was likely associated with ischemic stroke. We suggest the testing restricted to investigation of persistent presence of lupus anticoagulant. Copyright © 2015 Elsevier Ltd. All rights reserved.
Parenting Styles and Practices among Chinese Immigrant Mothers with Young Children
Chen, Jennifer Jun-Li; Chen, Tianying; Zheng, Xiao Xian
2012-01-01
This study investigated how Chinese immigrant mothers in the USA make meaning of their parenting styles and practices in rearing their young children (aged two to six). Twelve Chinese immigrant mothers were interviewed. A key finding reveals that the Chinese immigrant mothers' parenting practices reflected the indigenous concept of jiaoyang in the…
Developmental Differences in Young Children's Sex-Typing: Automatic versus Reflective Processing.
Perry, Louise C.; Sung, Hung-yen A.
To investigate social cognitive factors in early sex-role development, this study examined young children's gender-related judgments of toy appropriateness under speeded and delayed response conditions. Subjects were 55 boys and 59 girls, aged 3, 5, and 7. Ninety-two photographs of common toys were independently rated as mainly for girls, mainly…
Sport injuries of the knee in young people
Energy Technology Data Exchange (ETDEWEB)
Kainz, L; Brezina, K
1981-12-01
The largest number of injuries of the knee occurrs in athletes. The portion of girls has reached 30%. More than 50% of all injuries regard the ligaments and the menisci. Especially in these cases and in combined lesions, arthrography gives good results. All possibilities of investigations should be used for acutely injured sportsmen because of the specific risks and the dissimulation of young sportspeople and because of the danger of late established diagnosis and within those of late damages.
Techniques in Presenting Vocabulary to Young Efl Learners
Awaluddin, Annisa
2013-01-01
This paper reports on research results aimed at investigating the techniques used by a teacher of a young learner course in presenting meaning and form of vocabulary, as well as the reasons in employing the techniques. This study applied framework from Takač (2008). Observations and interview were carried out to collect the data. The findings indicate that the teacher applied various techniques with various reasons, both in presenting word meaning and form. In presenting word meaning, the tea...
Young drivers and their young passengers.
2015-01-01
More than one-third of all fatalities among car passengers occurs in the 10-24-year age group. The majority of these young passengers die in a car driven by an 18 to 24-year old. Compared with the composition of the population, these are high proportions, yet the exposure (for example in distance
Roux, Anne M.; Shattuck, Paul T.; Cooper, Benjamin P.; Anderson, Kristy A.; Wagner, Mary; Narendorf, Sarah C.
2013-01-01
Objective We examined postsecondary employment experiences of young adults with an autism spectrum disorder (ASD) and compared these outcomes with those of young adults with different disabilities. Method Data were from Wave 5 of the National Longitudinal Transition Study 2 (NLTS2), a nationally representative survey of young adults who had received special education services during high school. We examined the prevalence of ever having had—and currently having—a paid job at 21–25 years of age. We analyzed rates of full employment, wages earned, number of jobs held since high school, and job types. Results About half (53.4%) of young adults with an ASD had ever worked for pay outside the home since leaving high school, the lowest rate among disability groups. Young adults with an ASD earned an average of $8.10 per hour, significantly lower than average wages for young adults in the comparison groups, and held jobs that clustered within fewer occupational types. Odds of ever having had a paid job were higher for those who were older, from higher-income households, and with better conversational abilities or functional skills. Conclusions Findings of worse employment outcomes for young adults with an ASD suggest this population is experiencing particular difficulty in successfully transitioning into employment. Research is needed to determine strategies for improving outcomes as these young adults transition into adulthood. PMID:23972695
DEFF Research Database (Denmark)
Astakhova, I Kira; Wengel, Jesper
2013-01-01
Double-labeled oligonucleotide probes containing fluorophores interacting by energy-transfer mechanisms are essential for modern bioanalysis, molecular diagnostics, and in vivo imaging techniques. Although bright xanthene and cyanine dyes are gaining increased prominence within these fields, little...
Determinants of body fatness in young adults living in a Dutch community
Baecke, J.A.H.
1982-01-01
In 1979, the Department of Human Nutrition of the Agricultural University at Wageningen began a research project on obesity in young adults. The main objectives of this project are the investigation of aetiological aspects and health consequences of obesity. It is a prospective study and is being
Virtual Reality Social Cognition Training for Young Adults with High-Functioning Autism
Kandalaft, Michelle R.; Didehbani, Nyaz; Krawczyk, Daniel C.; Allen, Tandra T.; Chapman, Sandra B.
2013-01-01
Few evidence-based social interventions exist for young adults with high-functioning autism, many of whom encounter significant challenges during the transition into adulthood. The current study investigated the feasibility of an engaging Virtual Reality Social Cognition Training intervention focused on enhancing social skills, social cognition,…
Mild heat stress at a young age in Drosophila melanogaster leads to ...
Indian Academy of Sciences (India)
Unknown
effect on stress resistance later in life, and on longevity. ... bouts of mild heat stress (3 h at 34°C) at a young age (days 2, 4 and 6 post-eclosion) or held under .... The mortality during the investigated lifespan .... at least during early senescence.
Teacher and Peer Support for Young Adolescents' Motivation, Engagement, and School Belonging
Kiefer, Sarah M.; Alley, Kathleen M.; Ellerbrock, Cheryl R.
2015-01-01
The purpose of this sequential explanatory mixed methods study was to investigate teacher and peer support for young adolescents' academic motivation, classroom engagement, and school belonging within one large, urban, ethnically diverse middle school. In the initial quantitative phase, associations among aspects of teacher support (autonomy,…
Gender Differences in Beliefs about Condom Use among Young, Heterosexual Australian Adults
Newton, Fiona J.; Newton, Joshua D.; Windisch, Lydia; Ewing, Michael T.
2013-01-01
Objective: To investigate gender differences in beliefs about condom use among young, sexually active, heterosexual Australian adults. Design: Cross-sectional survey of 1,113 adults aged 18-26 years. Setting: Higher education institutions across New South Wales and Victoria, Australia. Method: Participants were recruited during higher-education…
Young Adolescents' Gender-, Ethnicity-, and Popularity-Based Social Schemas of Aggressive Behavior
Clemans, Katherine H.; Graber, Julia A.
2016-01-01
Social schemas can influence the perception and recollection of others' behavior and may create biases in the reporting of social events. This study investigated young adolescents' (N = 317) gender-, ethnicity-, and popularity-based social schemas of overtly and relationally aggressive behavior. Results indicated that participants associated overt…
Testing Selected Behaviors to Reduce Indoor Air Pollution Exposure in Young Children
Barnes, B. R.; Mathee, A.; Krieger, L.; Shafritz, L.; Favin, M.; Sherburne, L.
2004-01-01
Indoor air pollution is responsible for the deaths and illness of millions of young children in developing countries. This study investigated the acceptability (willingness to try) and feasibility (ability to perform) of four indoor air pollution reduction behaviors (improve stove maintenance practices, child location practices, ventilation…
Franck, Linda S; Noble, Genevieve
2007-12-01
Use of the internet to provide health information to young people is a relatively recent development. Few studies have explored young people's views on how they use internet health websites. This study investigated the navigation, design and content preferences of young people using the Children First for Health (CFfH) website. Young people from five secondary schools completed an internet site navigation exercise, website evaluation questionnaire and participated in informal discussions. Of the participants, 45 percent visited the website section aimed at older adolescents within their first two clicks, regardless of their age. There were conflicting preferences for design and strong preference for gender-specific information on topics such as appearance, relationships, fitness and sexual health. The findings indicate the importance of gaining young people's views to ensure that health information websites meet the needs of their intended audience. Cooperation from schools can facilitate the process of gaining young people's views on internet website navigation, design and content.
Evidence of Syndemics and Sexuality-Related Discrimination Among Young Sexual-Minority Women.
Coulter, Robert W S; Kinsky, Suzanne M; Herrick, Amy L; Stall, Ron D; Bauermeister, José A
2015-09-01
Syndemics, or the co-occurrence and interaction of health problems, have been examined extensively among young men who have sex with men, but their existence remain unexamined, to our knowledge, among sexual-minority (i.e., lesbian, gay, and bisexual) women. Thus, we investigated if syndemics were present among young sexual-minority women, and if sexual-orientation discrimination was an independent variable of syndemic production. A total of 467 sexual-minority women between the ages of 18 and 24 completed a cross-sectional online survey regarding their substance use, mental health, sexual behaviors, height, weight, and experiences of discrimination. We used structural equation modeling to investigate the presence of syndemics and their relationship to sexual-orientation discrimination. Heavy episodic drinking, marijuana use, ecstasy use, hallucinogen use, depressive symptoms, multiple sexual partners, and history of sexually transmitted infections (STIs) comprised syndemics in this population (chi-square=24.989, P=.201; comparative fit index [CFI]=0.946; root mean square error of approximation [RMSEA]=0.023). Sexual-orientation discrimination is significantly and positively associated with the latent syndemic variable (unstandardized coefficient=0.095, Pdiscrimination (unstandardized coefficient=0.602, P>.05). Syndemics appear to be present and associated with sexual-orientation discrimination among young sexual-minority women. Interventions aimed at reducing discrimination or increasing healthy coping may help reduce substance use, depressive symptoms, and sexual risk behaviors in this population.
Parents’ Traditional Cultural Values and Mexican-Origin Young Adults’ Routine Health and Dental Care
Updegraff, Kimberly A.; Kuo, Sally I-Chun; McHale, Susan M.; Umaña-Taylor, Adriana J.; Wheeler, Lorey A.
2017-01-01
Purpose To investigate the prospective associations between Mexican-origin mothers’ and fathers’ traditional cultural values and young adults’ health and dental care utilization and to test the moderating role of youth gender. Methods Mexican-origin parents and youth (N = 246 families) participated in home interviews and provided self-reports of parents’ cultural values (time 1) and young adults’ health status and routine health and dental care (time 2; 5 years later). Logistic regressions tested parents’ traditional cultural values as predictors of routine health and dental care, accounting for parent nativity, parent acculturation, family socioeconomic status, youth gender, youth age, and youth physical health status. We also tested whether youth gender moderated the associations between parents’ cultural values and young adults’ routine care. Results Young adults whose mothers endorsed strong familism values when they were in mid-to-late adolescence were more likely to report at least one routine physician visit in the past year as young adults (odds ratio [OR] = 3.47, 95% confidence interval [CI]: 1.23–9.83, p = .019). Furthermore, for females only, mothers’ more traditional gender role attitudes predicted reduced odds of receiving routine health (OR = .22; 95% CI: .08–.64, p = .005) and dental care (OR = .26; 95% CI: .09–.75, p = .012) in young adulthood. Conclusions Our findings highlight the importance of examining intragroup variability in culturally specific mechanisms to identify targets for addressing ethnic/racial disparities in health care utilization among Mexican-origin young adults, during a period of increased risk for health-compromising behaviors and reduced access to care. PMID:27988108
Directory of Open Access Journals (Sweden)
Naomi Berman
2012-03-01
Full Text Available This article presents the findings of an evaluation of an innovative Australian social entrepreneurship and leadership program to highlight some of the challenges young social change makers face as they attempt to influence change in their local, national and international environments. Through an investigation of an innovative Australian social entrepreneurship program, this article demonstrates how reflexive, communicative and participatory practices position young people at the forefront of new forms of civic engagement and that there are certain needs relating to the development of self and community which must to be addressed in order that these young social actors can fulfil their civic aspirations. The findings of the evaluation reported here demonstrate that if social entrepreneur programs are to be successful in providing a service to young people, they need to foster the creation of environments characterised by collectivism, collaboration and opportunities for self development while providing practical solutions to common barriers faced by social entrepreneurs
Directory of Open Access Journals (Sweden)
Duran Tok
2014-04-01
Full Text Available Objective: It has been reported that the neutrophil–lymphocyte ratio is significantly elevated in patients with low high-density lipoprotein cholesterol (<35 mg/dL. But in this study, some patients had hypertension that may have affected the neutrophil–lymphocyte ratio. This study consisted of 1274 asymptomatic healthy young men. In contrast with the previous study, we investigated the neutrophil–lymphocyte ratio in healthy young men with low high-density lipoprotein cholesterol compared with controls. Methods: We studied 1274 asymptomatic young males (military personnel screening who underwent routine health check-up. Of them, 102 subjects had low high-density lipoprotein cholesterol. Results: The neutrophil–lymphocyte ratio was significantly higher among the men with low high-density lipoprotein cholesterol than that of the control group (P < 0.001. Conclusion: We conclude that the neutrophil–lymphocyte ratio is significantly elevated in asymptomatic healthy young men with low high-density lipoprotein cholesterol compared with control participants.
Acute fluoxetine modulates emotional processing in young adult volunteers.
Capitão, L P; Murphy, S E; Browning, M; Cowen, P J; Harmer, C J
2015-08-01
Fluoxetine is generally regarded as the first-line pharmacological treatment for young people, as it is believed to show a more favourable benefit:risk ratio than other antidepressants. However, the mechanisms through which fluoxetine influences symptoms in youth have been little investigated. This study examined whether acute administration of fluoxetine in a sample of young healthy adults altered the processing of affective information, including positive, sad and anger cues. A total of 35 male and female volunteers aged between 18 and 21 years old were randomized to receive a single 20 mg dose of fluoxetine or placebo. At 6 h after administration, participants completed a facial expression recognition task, an emotion-potentiated startle task, an attentional dot-probe task and the Rapid Serial Visual Presentation. Subjective ratings of mood, anxiety and side effects were also taken pre- and post-fluoxetine/placebo administration. Relative to placebo-treated participants, participants receiving fluoxetine were less accurate at identifying anger and sadness and did not show the emotion-potentiated startle effect. There were no overall significant effects of fluoxetine on subjective ratings of mood. Fluoxetine can modulate emotional processing after a single dose in young adults. This pattern of effects suggests a potential cognitive mechanism for the greater benefit:risk ratio of fluoxetine in adolescent patients.
Obesity increases risk of ischemic stroke in young adults.
Mitchell, Andrew B; Cole, John W; McArdle, Patrick F; Cheng, Yu-Ching; Ryan, Kathleen A; Sparks, Mary J; Mitchell, Braxton D; Kittner, Steven J
2015-06-01
Body mass index has been associated with ischemic stroke in older populations, but its association with stroke in younger populations is not known. In light of the current obesity epidemic in the United States, the potential impact of obesity on stroke risk in young adults deserves attention. A population-based case-control study design with 1201 cases and 1154 controls was used to investigate the relationship of obesity and young onset ischemic stroke. Stroke cases were between the ages of 15 and 49 years. Logistic regression analysis was used to evaluate the association between body mass index and ischemic stroke with and without adjustment for comorbid conditions associated with stroke. In analyses adjusted for age, sex, and ethnicity, obesity (body mass index >30 kg/m(2)) was associated with an increased stroke risk (odds ratio, 1.57; 95% confidence interval, 1.28-1.94) although this increased risk was highly attenuated and not statistically significant after adjustment for smoking, hypertension, and diabetes mellitus. These results indicate that obesity is a risk factor for young onset ischemic stroke and suggest that this association may be partially mediated through hypertension, diabetes mellitus, or other variables associated with these conditions. © 2015 American Heart Association, Inc.
Ackard, Diann M; Richter, Sara; Egan, Amber; Cronemeyer, Catherine
2014-11-01
Eating disorders (EDs) present across a broad age range, yet little is known about the characteristics and outcome of midlife patients compared to younger patients. Among patients seeking ED treatment who were stratified by age at initial assessment (IA), this study aimed to (1) discern sociodemographic and clinical differences, (2) determine outcome rates, and (3) identify predictors of poor outcome including death. Participants [219 females (12 years or older, 94.1% Caucasian) who completed outcome assessment and 31 known decedents] were stratified by age at IA (young adult, and ≥40 years as midlife adult). Analyses of variance and chi-square tests identified group differences; ordered logistic regression with stepwise selection identified factors predicting outcome. Midlife adults were more significantly compromised at follow-up compared to youths and young adults, including psychological and physical quality of life, ineffectiveness, interpersonal concerns, and general psychological maladjustment. Midlife adults had the highest rates of poor outcome or death; good outcome was achieved by only 5.9% of midlife adult compared to 14.0% of young adult and 27.5% of youth patients. Older age at IA, alcohol and/or drug misuse, endocrine concerns, and absence of family ED history predicted poor outcome or death. Midlife adults seeking ED treatment have more complex medical and psychological concerns and poorer outcomes than youths and young adults; further exploration is needed to improve treatment outcome. Specialized treatment focusing on quality of life, comorbid medical concerns, interpersonal connection, and emotion regulation is encouraged. © 2014 Wiley Periodicals, Inc.
Investigation of the mechanical and electrical properties of superconducting coils
International Nuclear Information System (INIS)
Saito, T.; Yamagiwa, T.; Hara, K.; Kojima, Y.; Hosoyama, K.; Mori, A.; Nojima, K.; Okamoto, Y.; Takabayashi, S.; Tanaka, T.
1994-01-01
Measurement of elastic (Young's) modulus of the superconducting coil and electrical punch-through test have been performed at LBL to understand the mechanical and electrical properties of the superconducting coils. The authors have investigated the elastic modulus of the superconducting coils with six kinds of insulators (made with polyimide-fiberglass-epoxy and all polyimide insulation with epoxy/polyimide adhesive) at room and liquid nitrogen temperatures using samples made of 10 stacks of superconducting cables. The samples are cured under varying compression to investigate the curing pressure dependence of Young's modulus of the coils with six kinds of the insulation system. The electrical punch-through test has also performed under compression at room and liquid nitrogen temperatures to investigate electrical integrity of the insulated coils. The tensile strength test of four kinds of polyimide films has been performed at various temperatures (between cryogenic and coil curing temperatures) to understand the mechanical properties of the films
Young people's perspectives on health-related risks
Directory of Open Access Journals (Sweden)
Grace Elisabeth Spencer
2008-07-01
Full Text Available Drawing upon current socio-cultural understandings of risk, this study highlights the disjunction between the expert risk discourses that permeate official public health policy and practice, and young people’s own perspectives on health and risk. Data were collected from young people aged 14-16 years through the use of group and individual interviews in a school and community youth centre setting. Findings from this study question the saliency of expert-defined health-related risks to young people’s everyday lives. Young people in this study saw health as closely linked to ‘being happy’. Friendships and a sense of personal achievement were particularly important to participants’ health and well-being. When accounting for their participation in health-related practices identified as ‘risky’ in government policy – such as smoking, alcohol and substance use – young people emphasised the levels of pressure they experienced. Sources of pressure included arguments and bullying, school work, and negative stereotypes of young people in general. These areas indicated young people’s concerns that reach beyond the official prescriptions permeating current health policy.
L. ADAMS; T. FASEUR; M. GEUENS
2010-01-01
People’s self-regulatory focus may determine the effectiveness of stop-smoking campaigns. An experiment with 226 young smokers investigated the persuasiveness of different emotional appeals (fear-relief versus sadness-joy) for different self-regulatory foci (prevention versus promotion). A congruency effect emerges for attitude toward the advertisement and behavioral intentions: Young smokers with a promotion focus are more persuaded by sadness-joy than fear-relief campaigns, and the opposite...
Young Investigator Program: Modular Paradigm for Scalable Quantum Information
2016-03-04
actuator When both direct driving and a quantum controller are available, one can take advantage of both to achieve faster driving of the qubit. In...pointing to advantages to be found in particular geometries for larger quantum information architectures. • We investigated the effect of dephasing and...Montangero, T. Calarco, F. Nori, and M. B. Plenio, “Scal- able quantum computation via local control of only two qubits,” Phys. Rev. A, vol. 81, no. 4, p
[Vulvar squamous cell carcinoma in young women with HPV negative].
Gómez-Alarcon, A; Gómez-García, M T; García-de la-Torre, J P; Del Valle-Morón, M; Arones-Collantes, M A; González-de Merlo, G
2016-03-01
The vulvar cancer is the fourth more frequent neoplasia after the endometrial, cervix and ovarian cancer. Normally, it has been related to old women of ages from 70 to 80 years old. Rarely, it has been detected cases in adult or young women. However, its incidence has been increased in the last years and in more early years. It is for this change in the incidence and its appearance in early years why a possible etiology has been looked for, opening different hypothesis that go from that related to the HPV to those that study an inflammatory chronic process as the basis for the carcinogenesis. In this article, it has been presented the case of a woman who is 34 years old with negative VPH that made her debut with epidermoid carcinoma of the vulva moderately different and on purpose of the case, we do a revision of the literature existent. Vulvar cancer diagnosed in young women as in older, but with different trends, risk factors and natural history. The case reported here escapes the theories studied so far so needed new lines of inquiry to investigate this form of presentation young woman, without HPV infection.
Creating intoxigenic environments: marketing alcohol to young people in Aotearoa New Zealand.
McCreanor, Tim; Barnes, Helen Moewaka; Kaiwai, Hector; Borell, Suaree; Gregory, Amanda
2008-09-01
Alcohol consumption among young people in New Zealand is on the rise. Given the broad array of acute and chronic harms that arise from this trend, it is a major cause for alarm and it is imperative that we improve our knowledge of key drivers of youth drinking. Changes wrought by the neoliberal political climate of deregulation that characterised the last two decades in many countries including Aotearoa (Aotearoa is a Maori name for New Zealand) New Zealand have transformed the availability of alcohol to young people. Commercial development of youth alcohol markets has seen the emergence of new environments, cultures and practices around drinking and intoxication but the ways in which these changes are interpreted and taken up are not well understood. This paper reports findings from a qualitative research project investigating the meaning-making practices of young people in New Zealand in response to alcohol marketing. Research data included group interviews with a range of Maori and Pakeha young people at three time periods. Thematic analyses of the youth data on usages of marketing materials indicate naturalisation of tropes of alcohol intoxication. We show how marketing is used and enjoyed in youth discourses creating and maintaining what we refer to as intoxigenic social environments. The implications are considered in light of the growing exposure of young people to alcohol marketing in a discussion of strategies to manage and mitigate its impacts on behaviour and consumption.
Burke, Kylie; Brennan, Leah; Cann, Warren
2012-01-01
This study examined the efficacy of a program for parents of young adolescents combining behavioral family intervention with acceptance-based strategies. 180 parents were randomly allocated to a 6-session group ABCD Parenting Young Adolescent Program or wait-list condition. Completer analysis indicated parents in the intervention reported…
Keenan-Mount, Rebekah; Albrecht, Nicole Jacqueline; Waters, Lea
2016-01-01
Parents and teachers who care for and educate young people with Autism Spectrum Disorder (ASD) face unique challenges associated with their roles. In this review we investigated the efficacy of mindfulness-based interventions in reducing stress and increasing positive behaviours in young people with ASD and their caregivers: parents and teachers.…
DEFF Research Database (Denmark)
Bandholm, Thomas; Rose, Martin Høyer; Sonne-Holm, Stig
2008-01-01
It was the primary objective of this study to investigate whether quantifying fluctuations in dorsi and plantarflexor torque during submaximal isometric contractions is a reliable measurement in young healthy subjects. A secondary objective was to investigate the reliability of the associated mus...
Carroll, Catherine; Dockrell, Julie
2012-01-01
Research studies have begun to investigate the post-16 outcomes for young adults with a specific language impairment (SLI). As yet only tentative conclusions can be drawn with respect to academic and employment outcomes and the factors that are associated with more positive outcomes. Evidence for these findings has relied predominantly on associations between various language, academic and psychosocial assessments. Little attention has been paid to the perspective of the young person. To investigate from the perspective of a group of young people with a history of SLI the factors they believed have enabled and presented a challenge to their post-16 education and employment outcomes and experiences. Nineteen (four female, 15 male) young people aged from 19 to 23 years (average age 21 years), who had all attended the same residential special school for pupils with SLI, were interviewed face to face to explore their views as to what had enabled and limited their transition experiences to date. The data were analysed using thematic analysis. The majority of the young people saw themselves as key agents of change and very active participants in steering their own transition since leaving school. They acknowledged the important role played by their parents and families and how factors such as SLI had affected their transition experiences. The study supports evidence from research with different groups of young people with special educational needs (SEN) and disabilities of the importance of school and post-16 curriculums which develop agency on behalf of the young person. © 2012 Royal College of Speech and Language Therapists.
Nicotine dependence and sleep quality in young adults.
Dugas, E N; Sylvestre, M P; O'Loughlin, E K; Brunet, J; Kakinami, L; Constantin, E; O'Loughlin, J
2017-02-01
More cigarette smokers report poor sleep quality than non-smokers, but the association between nicotine dependence (ND) and sleep quality has not been well-characterized. The objective of this study was to describe the associations among frequency and intensity of cigarette smoking, ND symptoms, and sleep quality in young adults. Data on past-year smoking frequency, number of cigarettes smoked in the past month, five ND indicators (i.e., withdrawal, craving, self-medication symptoms, mFTQ, ICD-10 criteria for tobacco dependence), and sleep quality (measured with the Pittsburgh Sleep Quality Index (PSQI)) were collected in 2011-12 in self-report questionnaires completed by 405 young adult smokers (mean age 24 (0.6) years; 45% male; 45% daily smokers) participating in a longitudinal investigation of the natural course of ND. Associations between indicators of cigarette smoking, ND symptoms, and sleep quality were examined in multivariable logistic regression analyses controlling for age, sex, mother's education, and alcohol use. Thirty-six percent of participants reported poor sleep quality (PSQI>5). Higher cigarette consumption (OR(95% CI), 1.03(1.001-1.05)) but not frequency of past-year smoking, more frequent withdrawal symptoms (1.05(1.004-1.10)), more frequent cravings (1.05(1.004-1.10)), higher mFTQ scores (1.14(1.02-1.27)), and endorsing more ICD-10 criteria for tobacco dependence (1.19(1.04-1.36)) were also associated with poor sleep quality. Cigarette smoking and ND symptoms are associated with poor sleep quality in young adult smokers. Advice from practitioners to cut back on number of cigarettes smoked per day and treatment of ND symptoms may improve sleep quality in young adult smokers. Copyright © 2016 Elsevier Ltd. All rights reserved.
International Nuclear Information System (INIS)
Oku, T.; Usui, T.; Ero, M.; Fukuda, Y.
1977-01-01
The Young's moduli of unirradiated and high temperature (800 to 1000 0 C) irradiated graphites for HTGR were measured by the ultrasonic method in the direction of applied compressive stress during and after stressing. The Young's moduli of all the tested graphites decreased with increasing compressive stress both during and after stressing. In order to investigate the reason for the decrease in Young's modulus by applying compressive stress, the mercury pore diameter distributions of a part of the unirradiated and irradiated specimens were measured. The change in pore distribution is believed to be associated with structural changes produced by irradiation and compressive stressing. The residual strain, after removing the compressive stress, showed a good correlation with the decrease in Young's modulus caused by the compressive stress. The decrease in Young's modulus by applying compressive stress was considered to be due to the increase in the mobile dislocation density and the growth or formation of cracks. The results suggest, however, that the mechanism giving the larger contribution depends on the brand of graphite, and in anisotropic graphite it depends on the direction of applied stress and the irradiation conditions. (author)
Serious, Violent Young Offenders in South Africa : Are They Life-Course Persistent Offenders?
Souverein, F.A.; Ward, C.L.; Visser, I.; Burton, P.
2016-01-01
Life-course persistent offending contributes greatly to violent offending in any country. South Africa has high rates of violence; this study investigated what proportion of young South African offenders might be identified as life-course persistent, and what risk factors identified this group.
Be a Bee and Other Approaches To Introducing Young Children to Entomology.
Danoff-Burg, James A.
2002-01-01
Early and ongoing exposure to entomology promotes interest in insects, minimizes fear of nature, and instills appreciation for biodiversity. Three effective ways to introduce young children to the study of insects are: live collections for observation and investigation, re-creation of insects through artistic constructions to learn structure and…
Promoting Word Consciousness to Close the Vocabulary Gap in Young Word Learners
Neugebauer, Sabina Rak; Gámez, Perla B.; Coyne, Michael D.; McCoach, D. Betsy; Cólon, Ingrid T.; Ware, Sharon
2017-01-01
A proposed avenue for increasing students' vocabulary knowledge and reading comprehension is instruction that promotes students' enthusiasm and attention to words, referred to as "word consciousness". This study seeks to investigate, at the utterance level, whether and how word consciousness talk is used in classrooms with young word…
Autistic Traits and Cognitive Performance in Young People with Mild Intellectual Impairment
Harris, Jonathan M.; Best, Catherine S.; Moffat, Vivien J.; Spencer, Michael D.; Philip, Ruth C. M.; Power, Michael J.; Johnstone, Eve C.
2008-01-01
Cognitive performance and the relationship between theory of mind (TOM), weak central coherence and executive function were investigated in a cohort of young people with additional learning needs. Participants were categorized by social communication questionnaire score into groups of 10 individuals within the autistic spectrum disorder (ASD)…
Everyday Experiences of Homeless Young People in Supported Accommodation Programmes in Australia
Danby, Susan; Farrell, Ann; Leiminer, Michele
2006-01-01
This paper investigates young people's accounts of governance in their everyday lives within a Supported Accommodation Assistance Program (SAAP) in regional Australia. The SAAP is a joint Commonwealth and State/Territory programme for assisting people who are homeless or at risk of homelessness by providing transitional supported accommodation and…
Fattori, Francesco; Curly, Simone; J?rchel, Amrei C.; Pozzi, Maura; Mihalits, Dominik; Alfieri, Sara
2015-01-01
Obedience and disobedience have always been salient issues for both civil society and social psychologists. Since Milgram’s first studies on destructive obedience there has not been a bottom-up definition of what obedience and disobedience mean. The current study aimed at investigating the social representations young adults use to define and to co-construct knowledge about obedience and disobedience in Austria. One hundred fifty four (106 females, 68.8%) Austrian young adults (Mean age = 22....
Designing a packaging to promote healthy and low-fat foods: Adolescents versus young-adults.
Vila-López, Natalia; Küster-Boluda, Ines; Sarabia-Sánchez, Francisco
2017-09-01
Packaging is a relevant tool when adolescents and young adults search for low-fat and healthy foods. However, the power of a packaging is not homogenous. In this framework, two main objectives guide our work: (i) to investigate to what extent visual cues (size, colors, images etc.) are more important than informational cues (label); (ii) to analyze if adolescents and young adults pay equal attention to both packaging cues. 590 adolescents between 12 and 18years of age were interviewed at the door of both public and private schools. Additionally, 300 young adults between 19 and 25years of age were contacted. Their opinions were analyzed twice using structural modelling techniques: (i) without considering age differences and (ii) splitting the sample into adolescents (590 participants) and young-adults (300 participants) to compare their perceptions. Our results have showed that when looking for healthy and low-fat aliments visual cues (size, colors, images etc.) are more important than informational cues (label design, easily understandable words, size of the letters). Additionally, age is a pertinent variable to explain alternative packaging strategies, because adolescents and young adults do not pay equal attention to both packaging cues. Copyright © 2017. Published by Elsevier Ltd.
Promoting physical activity of adolescent and young Iranian girls
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Fatemeh Rajabi
2018-01-01
Full Text Available Background: Women play a central role in the health of the whole family, but they are faced with more barriers while taking part in physical activities. Methods: This study was composed of two main phases. In the first phase, the status of physical activity among young and adolescent in Iran and global evidence of effective interventions were searched. In the second phase, Focused Group Discussion (FGD sessions were held with the key stakeholders in Tehran to investigate the results obtained from the first phase. Results: Physical activity among young and adolescent in Iran is inadequate. Based on the results obtained from the evidence and analysis of the FGDs, solutions defined as supporting policies, supporting environment, and supporting programs for physical activities. Conclusions: Multilevel cooperation among schools, families, and society is necessary to develop and implement policies and supporting programs, with an emphasis on combined interventions.
Following basal stem rot in young oil palm plantings.
Panchal, G; Bridge, P D
2005-01-01
The PCR primer GanET has previously been shown to be suitable for the specific amplification of DNA from Ganoderma boninense. A DNA extraction and PCR method has been developed that allows for the amplification of the G. boninense DNA from environmental samples of oil palm tissue. The GanET primer reaction was used in conjunction with a palm-sampling programme to investigate the possible infection of young palms through cut frond base surfaces. Ganoderma DNA was detected in frond base material at a greater frequency than would be expected by comparison with current infection levels. Comparisons are made between the height of the frond base infected, the number of frond bases infected, and subsequent development of basal stem rot. The preliminary results suggest that the development of basal stem rot may be more likely to occur when young lower frond bases are infected.
The molecular autopsy: an indispensable step following sudden cardiac death in the young?
Boczek, Nicole J.; Tester, David J.; Ackerman, Michael J.
2013-01-01
Annually thousands of sudden deaths involving young individuals (autopsy. In fact, epidemiological studies have estimated that over half of sudden deaths involving previously healthy young individuals have no morphological abnormalities identifiable at autopsy. Cardiac channelopathies associated with structurally normal hearts such as long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), and Brugada syndrome (BrS), leave no evidence to be found at autopsy, leaving investigators to only speculate that a lethal arrhythmia might lie at the heart of a sudden unexplained death (SUD). In cases of autopsy-negative SUD, continued investigation, through the use of a cardiological and genetic evaluation of first- or second-degree relatives and/or a molecular autopsy, may pinpoint the underlying mechanism attributing to the sudden death and allow for the identification of living family members with the pathogenic substrate that renders them vulnerable to an increased risk for cardiac events, including sudden death. PMID:22993115
Strokes in young adults: epidemiology and prevention
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Smajlović D
2015-02-01
Full Text Available Dževdet Smajlović Department of Neurology, University Clinical Centre Tuzla, School of Medicine, University of Tuzla, Bosnia and Herzegovina Abstract: Strokes in young adults are reported as being uncommon, comprising 10%–15% of all stroke patients. However, compared with stroke in older adults, stroke in the young has a disproportionately large economic impact by leaving victims disabled before their most productive years. Recent publications report an increased incidence of stroke in young adults. This is important given the fact that younger stroke patients have a clearly increased risk of death compared with the general population. The prevalence of standard modifiable vascular risk factors in young stroke patients is different from that in older patients. Modifiable risk factors for stroke, such as dyslipidemia, smoking, and hypertension, are highly prevalent in the young stroke population, with no significant difference in geographic, climatic, nutritional, lifestyle, or genetic diversity. The list of potential stroke etiologies among young adults is extensive. Strokes of undetermined and of other determined etiology are the most common types among young patients according to TOAST (Trial of Org 10172 in Acute Stroke Treatment criteria. Prevention is the primary treatment strategy aimed at reducing morbidity and mortality related to stroke. Therefore, primary prevention is very important with regard to stroke in young adults, and aggressive treatment of risk factors for stroke, such as hypertension, smoking, and dyslipidemia, is essential. The best form of secondary stroke prevention is directed toward stroke etiology as well as treatment of additional risk factors. However, there is a lack of specific recommendations and guidelines for stroke management in young adults. In conclusion, strokes in young adults are a major public health problem and further research, with standardized methodology, is needed in order to give us more
Sustaining dignity? food insecurity in homeless young people in urban Australia.
Crawford, Belinda; Yamazaki, Rowena; Franke, Elise; Amanatidis, Sue; Ravulo, Jioji; Steinbeck, Kate; Ritchie, Jan; Torvaldsen, Siranda
2014-08-01
Food insecurity is recognised as an increasing problem in disadvantaged and marginalised groups. The aim of this study was to investigate issues associated with food insecurity and nutrition in young people experiencing, or at risk of, homelessness in metropolitan Australia. Eight focus group discussions were conducted with 48 young people (aged between 15 and 25 years) in specialist homelessness services in central and south-western Sydney. Participants described daily experiences of food insecurity, persistent hunger and poverty. Structural barriers to food security and nutrition were identified and included poverty and reduced physical access to fresh foods. Participants also described a desire to save time, for convenience and to be socially connected. Despite the hardships and the chaos of youth homelessness, the groups were defined by their strength of character, resilience and hope for the future. Homeless young people within central and south-western Sydney report varying degrees of food insecurity, despite being supported by specialist youth homelessness services. SO WHAT? A collaborative, multistrategic approach with youth participation is required to further enhance the capacity of youth services to improve food security, food access and the availability of nutritious foods for homeless young people. A greater focus on advocacy and policy action is also required to bring food security and nutrition to the forefront of national efforts to improve the health and welfare of disadvantaged groups.
VOLUME OF PHYSICAL ACTIVITY AND INJURY OCCURRENCE IN YOUNG BASKETBALL PLAYERS
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Jenny Gianoudis
2008-03-01
Full Text Available Participation in organised, competitive physical activity by young athletes is increasing rapidly. This is concurrent with an increase in sporting injuries in the young population. This pilot study aimed to compare the weekly volume and types of physical activity in young basketball players injured and not injured during the season. Detailed physical activity and injury data were prospectively collected in 46 school-level basketball players aged 14 to 18 years. Participants completed physical activity logs which documented the type of physical activity undertaken, what the activity consisted of (i.e. training, competition and the level at which it was played on a daily basis. Allied health staff completed a weekly injury form. Results showed that injured and uninjured athletes participated in a similar volume of total weekly physical activity over the season. However, injured athletes (p = 0.04 and athletes who specifically sustained overuse injuries (p = 0.01 participated in a greater amount of basketball refereeing than uninjured athletes. Based on these findings it was concluded that greater participation in running-type physical activity such as refereeing, as an addition to training and competition, may predispose the young basketball player to increased injury risk. Future research using larger sample sizes are required to further investigate the role of participation volume and type on injury occurrence in adolescent athletes
Signed Young Modules and Simple Specht Modules
Danz, Susanne; Lim, Kay Jin
2015-01-01
By a result of Hemmer, every simple Specht module of a finite symmetric group over a field of odd characteristic is a signed Young module. While Specht modules are parametrized by partitions, indecomposable signed Young modules are parametrized by certain pairs of partitions. The main result of this article establishes the signed Young module labels of simple Specht modules. Along the way we prove a number of results concerning indecomposable signed Young modules that are of independent inter...
Surgical Consideration for Adolescents and Young Adults With Cervical Chordoma.
Zhong, Nanzhe; Yang, Xinghai; Yang, Jian; Meng, Tong; Yang, Cheng; Yan, Wangjun; Xiao, Jianru
2017-05-15
Retrospective study. The aim of this study was to compare the clinical outcomes between adolescent and young adult (AYA) patients and old adult patients with cervical chordoma who were treated surgically and present the surgical consideration for adolescents and young adults with cervical chordoma. With predominance in senior patients, chordoma is distinctively rare in AYAs. Because of the rarity of AYA chordoma, individual case report represents most of the literature on this disease entity on mobile spine and lack of long-term follow up, which leads to the paucity of clinical evidence for treatment planning and prognosis prediction. A retrospective study was conducted to investigate the prognosis of AYA patients with cervical chordoma who were treated surgically. We collected the clinical data of these patients and their older counterparts, and further compared the prognosis of the patients in different age groups. To estimate survival curves, Kaplan-Meier method was used, and significance was assessed using a log-rank test. Forty consecutive patients with chordoma of the cervical spine treated in our institution were included in the study. Two groups were identified according to age. Group 1 comprised children and adolescents (age ≤ 25 yrs; n = 9) and Group 2 comprised adults (age > 25 years; n = 31). In comparison, Group 1 was featured by significantly higher rate of recurrence and shorter overall survival, although no difference found in the surgical modality between two groups. There is a dismal prognosis in young patients with chordoma, and thus support the notion that as radical a total en bloc spondylectomy (TES) of the lesions as possible may benefit the overall survival of these young patients. Although the ensuing neurological deficits may be devastating, it will be worth sacrificing if the life expectancy of these young patients is prolonged. 4.
Suicidal expressions in young Swedish Sami, a cross-sectional study
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Lotta Omma
2013-01-01
Full Text Available Objectives. To investigate the experience of suicidal expressions (death wishes, life weariness, ideation, plans and attempts in young Swedish Sami, their attitudes toward suicide (ATTS, and experience of suicidal expressions and completed suicide in significant others and to compare with Swedes in general. Methods. A cross-sectional study comprising 516 Swedish Sami, 18–28 years of age together with an age and geographically matched reference group (n=218. Parts of the ATTS questionnaire have been used to cover different aspects of the suicidal complex.Data were analysed with regard to gender, occupation, counties and experience of negative societal treatment due to Sami background. Results. Both young Sami and young Swedes reported suicidal ideation, life weariness, and death wishes in a high degree (30–50%, but it was more common among the Sami. Having had plans to commit suicide showed a significant gender difference only in the Sami. The prevalence of suicide attempts did not differ significantly between Sami and Swedes. Subgroups of the Sami reported a higher degree of suicidal behaviour, Sami women and reindeer herders reported a 3, 5-fold higher odds of suicide attempts and a 2-fold higher odds having had plans committing suicide. Sami living in Vasterbotten/Jamtland/Vasternorrland and Sami with experience of ethnicity related bad treatment 2-fold higher odds of suicidal plans compared to those living in other counties. Conclusion. An increased occurrence of suicidal ideation/death wishes/life weariness in young Sami compared to young majority Swedes was found, but not an increased prevalence of suicide attempts and positive attitudes together with an increased awareness to handle suicide problems could be a contributing factor. Severe circumstances and experience of ethnicity-related bad treatment seems to contribute to increased levels of suicidal plans and attempts in subgroups of Sami.
Teenage pregnancy prevention: the role of young men.
Vargas, Gabriela; Borus, Joshua; Charlton, Brittany M
2017-08-01
Although teenage pregnancy is declining in many parts of the world, it remains associated with considerable social, health, and economic outcomes. Pregnancy prevention efforts focus primarily on young women, with minimal attention to young men. This review highlights recent literature pertaining to the role of young men in pregnancy prevention. Young men have varying views on contraception as well as which partner(s) should be responsible for its use. Limited contraception knowledge reduces young men's sexual health communication as well as their contraception use. Healthcare providers play a major role as one of the main sources of sexual health information for young men, but there are gaps in young men's sexual health care so new guidelines have emerged. Recent literature highlights young men's range of views on contraception as well as their low sexual health knowledge and sexual health communication. To address teenage pregnancy and improve young men's overall wellness, healthcare providers should routinely address sexual health. Healthcare providers may use our newly proposed acronym, HIS BESTT, (Hello. Initiate. Sexual health assessment. Both condoms and female dependent methods. Examine genitals. STI screening. Talking to partner(s). Talking to parent(s) or guardians), to incorporate current clinical recommendations.
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H. Galal El-Din
2011-11-01
Full Text Available This international comparative study between talented young handball players in Germany and Greece investigated specific physical and anthropometric characteristics. This investigation of both elite profiles will allow us to determine the differences in the selection system for elite young handball players between the two countries. One hundred and sixty-two players participated in this study, 88 Greek young male players and 74 German young male players. For anthropometric tests the players were measured for body height, body mass and body mass index, arm span, hand length and hand spread. Physical fitness measurements were 30 m sprint, standing long jump, sit and reach flexibility, and 20 m shuttle run test. The results of this study demonstrate that Greek players were taller and heavier (p<0.01, had longer arm span and hand length (p<0.01, and performed better in 30 m sprint (p<0.01, standing long jump (p<0.01 and aerobic capacity (p<0.01. German players outperform in hand spread (p=0.03. While some of these differences can be explained by the different strategies and training methods, and also the training environment, the results do have important implications and effects in the physical condition of junior players.
Social modulation of stress reactivity and learning in young worker honey bees.
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Elodie Urlacher
Full Text Available Alarm pheromone and its major component isopentylacetate induce stress-like responses in forager honey bees, impairing their ability to associate odors with a food reward. We investigated whether isopentylacetate exposure decreases appetitive learning also in young worker bees. While isopentylacetate-induced learning deficits were observed in guards and foragers collected from a queen-right colony, learning impairments resulting from exposure to this pheromone could not be detected in bees cleaning cells. As cell cleaners are generally among the youngest workers in the colony, effects of isopentylacetate on learning behavior were examined further using bees of known age. Adult workers were maintained under laboratory conditions from the time of adult emergence. Fifty percent of the bees were exposed to queen mandibular pheromone during this period, whereas control bees were not exposed to this pheromone. Isopentylacetate-induced learning impairments were apparent in young (less than one week old controls, but not in bees of the same age exposed to queen mandibular pheromone. This study reveals young worker bees can exhibit a stress-like response to alarm pheromone, but isopentylacetate-induced learning impairments in young bees are suppressed by queen mandibular pheromone. While isopentylacetate exposure reduced responses during associative learning (acquisition, it did not affect one-hour memory retrieval.
Social Modulation of Stress Reactivity and Learning in Young Worker Honey Bees
Mercer, Alison R.
2014-01-01
Alarm pheromone and its major component isopentylacetate induce stress-like responses in forager honey bees, impairing their ability to associate odors with a food reward. We investigated whether isopentylacetate exposure decreases appetitive learning also in young worker bees. While isopentylacetate-induced learning deficits were observed in guards and foragers collected from a queen-right colony, learning impairments resulting from exposure to this pheromone could not be detected in bees cleaning cells. As cell cleaners are generally among the youngest workers in the colony, effects of isopentylacetate on learning behavior were examined further using bees of known age. Adult workers were maintained under laboratory conditions from the time of adult emergence. Fifty percent of the bees were exposed to queen mandibular pheromone during this period, whereas control bees were not exposed to this pheromone. Isopentylacetate-induced learning impairments were apparent in young (less than one week old) controls, but not in bees of the same age exposed to queen mandibular pheromone. This study reveals young worker bees can exhibit a stress-like response to alarm pheromone, but isopentylacetate-induced learning impairments in young bees are suppressed by queen mandibular pheromone. While isopentylacetate exposure reduced responses during associative learning (acquisition), it did not affect one-hour memory retrieval. PMID:25470128
Anatomical brain difference of subthreshold depression in young and middle-aged individuals.
Li, Jing; Wang, Zengjian; Hwang, JiWon; Zhao, Bingcong; Yang, Xinjing; Xin, Suicheng; Wang, Yu; Jiang, Huili; Shi, Peng; Zhang, Ye; Wang, Xu; Lang, Courtney; Park, Joel; Bao, Tuya; Kong, Jian
2017-01-01
Subthreshold depression (StD) is associated with substantial functional impairments due to depressive symptoms that do not fully meet the diagnosis of major depressive disorder (MDD). Its high incidence in the general population and debilitating symptoms has recently put it at the forefront of mood disorder research. In this study we investigated common volumetric brain changes in both young and middle-aged StD patients. Two cohorts of StD patients, young and middle-aged, ( n = 57) and matched controls ( n = 76) underwent voxel-based morphometry (VBM). VBM analysis found that: 1) compared with healthy controls, StD patients showed decreased gray matter volume (GMV) in the bilateral globus pallidus and precentral gyrus, as well as increased GMV in the left thalamus and right rostral anterior cingulate cortex/medial prefrontal cortex; 2) there is a significant association between Center for Epidemiological Studies Depression Scale scores and the bilateral globus pallidus (negative) and left thalamus (positive); 3) there is no interaction between age (young vs. middle-age) and group (StD vs. controls). Our findings indicate significant VBM brain changes in both young and middle-aged individuals with StD. Individuals with StD, regardless of age, may share common neural characteristics.
Bastien, Sheri
2008-01-01
This paper investigates the reasons why young people in urban and rural Kilimanjaro, Tanzania do not attend school, their socio-demographic characteristics, AIDS knowledge and risk perception. A structured face-to-face interview was conducted with 1007 young people between the ages of 13 and 18. Findings suggest that non-attendance is the product…
Abebe, Dawit Shawel; Torgersen, Leila; Lien, Lars; Hafstad, Gertrud S.; von Soest, Tilmann
2014-01-01
We investigated longitudinal predictors for disordered eating from early adolescence to young adulthood (12-34 years) across gender and different developmental phases among Norwegian young people. Survey data from a population-based sample were collected at four time points (T) over a 13-year time span. A population-based sample of 5,679 females…
Young Adults Failure to Thrive Syndrome
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Warren C. Sanderson
2014-03-01
Full Text Available Many young working age adults in developed countries are failing to thrive in economic, demographic and social terms. Their failure to thrive is a relatively new phenomenon that has not been widely recognized, but it affects young adults in virtually all the more developed countries for which we have relevant data. Young adults nowadays are more often in poverty. They are leaving their parental homes at ever later ages and in some countries the frequency of psychological problems increased. The seriousness of failure to thrive syndrome is reflected in the relationship between relative economic conditions and increased suicide rates. The syndrome is important because young adults are at the prime ages for finding employment, establishing long-run career paths and building an economic basis for founding a family. Developing strategies to arrest the spread of failure to thrive syndrome among young adults, in order to keep them vibrant contributors to our societies, should be a priority for policy makers.
Young people and sexual orientation
Lisette Kuyper
2015-01-01
Original title: Young people and sexual orientation The Netherlands Institute for Social Research ¦ SCP carries out regular research on lesbian, gay, bisexual and transgender (LGBT) individuals. In this report, the focus is on young people in the Netherlands. The report addresses two issues:
Nutritional supplement use by elite young UK athletes: fallacies of advice regarding efficacy
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Bloodworth Andrew
2008-12-01
Full Text Available Abstract Background The objective was to study nutritional supplement use among young elite UK athletes to establish whether a rationale versus practice incongruence exists, and to investigate the sources of information. Survey data were analysed for association between supplements used and motives for using such substances among young athletes along with the sources of advice and literature precedents on supplement effects. Methods Participants were elite UK male and female athletes, within the age range between 12 and 21 (n = 403, mean age 17.66 ± 1.99. Associations between type of supplements and reasons for using supplements were tested by calculating Pearson's χ2 and the strength of these symmetric associations shown by phi (ϕ association coefficients. Results Single supplement use was reported by 48.1%, with energy drinks being the most popular, consumed by 41.7% of all athletes and 86.6% of the supplement users in the sample. No agreement was observed between athletes' rationale and behaviour in relation to nutritional supplements except for creatine. Among health professionals, nutritionists and physiotherapists, followed by coaches, were most frequently consulted. Answers regarding reasons and supplements used showed incongruence and suggest widespread misinformation regarding supplements and their effects is an issue for the young athlete. Conclusion Widespread supplement taking behaviour was evidenced in the young elite athlete population with the most notable congruence between rationale and practice among young athletes being performance-related. Young athletes in the present sample appear to be less 'health conscious' and more 'performance focused' than their adult counterparts. Further research, using a full list of supplements, is warranted to test the hypothesis that health consciousness is less dominant in supplement choice by young athletes.
Miller, Peter G; Butler, Erin; Richardson, Ben; Staiger, Petra K; Youssef, George J; Macdonald, Jacqui A; Sanson, Ann; Edwards, Ben; Olsson, Craig A
2016-05-01
Heavy episodic drinking (HED) has been associated with increased risk for short- and long-term injury and harms, such as violence and delinquent behaviour; however, the temporal relationship between the two remains unclear, particularly on transition to young adulthood. This study investigates transactional pathways between HED and delinquent behaviour from adolescence to emerging adulthood. Data were drawn from the Australian Temperament Project; a population-based longitudinal study that has followed the health and development of participants (and parents) across 30 years from birth in 1982. The analytic sample was 1650 participants and included five measurement waves spanning adolescence (3 waves: 13-18 years) and young adulthood (2 waves; 19-24 years). There was strong continuity across waves of both HED and delinquency, as well as across-time associations between them. Delinquent behaviour in adolescence was associated with up to twofold increases in the odds of HED at each subsequent adolescent wave. HED in the late teens was associated with over fourfold increases in the odds of persistent (two waves) HED in young adulthood. HED in the late teens was associated with increases in the odds of delinquent behaviour in young adulthood (over twofold for male and one and a half-fold for female participants). While delinquent behaviour predicts both future HED and future delinquent behaviour in adolescence, once young people reach the legal drinking age of 18 years, HED becomes a predictor of current and future delinquent behaviour and future HED, suggesting that increased access to alcohol increases the likelihood of young people engaging in delinquent behaviour. [Miller PG, Butler E, Richardson B, Staiger PK, Youssef GJ, Macdonald JA, Sanson A, Edwards B, Olsson CA. Relationships between problematic alcohol consumption and delinquent behaviour from adolescence to young adulthood. Drug Alcohol Rev 2016;35:317-325]. © 2015 Australasian Professional Society on
Sporting Clubs, Alcohol and Young People: Enduring Tensions and Emerging Possibilities
Hickey, Christopher; Kelly, Peter; Cormack, Sue; Harrison, Lyn; Lindsay, Jo
2009-01-01
This paper examines data from a research project that investigated the cultural drivers of drinking in 14-24 year-old Australians, funded by Drinkwise Australia and the Department of Health and Ageing. At the same time that we were working on this project a moral panic about young people, risk and binge drinking had once more energised public…
Identifying Determinants of Young Children's Brand Awareness: Television, Parents, and Peers
Valkenburg, P.M.; Buijzen, M.
2005-01-01
The aim of this study was to investigate the development of young children's brand awareness, and the relative influence of environmental factors (e.g., television, parents, peers) on brand awareness. We presented 196 two- to eight-year-olds with 12 brand logos. After exposure to these logos, we asked children to mention the brand name (brand…
Basit, Tehmina N.
2012-01-01
This article investigates retrospectively and prospectively the educational and career aspirations and experiences of young minority ethnic British citizens. It focuses on one aspect of a larger mixed methods study, that is, qualitative research involving in-depth interviews with a stratified sample of 20 young men and women of minority ethnic…
CARBOHYDRATE INTAKE CONSIDERATIONS FOR YOUNG ATHLETES
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Veronica Montfort-Steiger
2007-09-01
Full Text Available Good nutritional practices are important for exercise performance and health during all ages. Athletes and especially growing children engaged in heavy training have higher energy and nutrient requirements compared to their non-active counterparts. Scientific understanding of sports nutrition for the young athlete is lacking behind the growing number of young athletes engaged in sports. Most of the sports nutrition recommendations given to athletic children and adolescents are based on adult findings due to the deficiency in age specific information in young athletes. Therefore, this review reflects on child specific sports nutrition, particularly on carbohydrate intake and metabolism that distinguishes the child athlete from the adult athlete. Children are characterised to be in an insulin resistance stage during certain periods of maturation, have different glycolytic/metabolic responses during exercise, have a tendency for higher fat oxidation during exercise and show different heat dissipation mechanisms compared to adults. These features point out that young athletes may need different nutritional advice on carbohydrate for exercise to those from adult athletes. Sport drinks for example may need to be adapted to children specific needs. However, more research in this area is warranted to clarify sports nutrition needs of the young athlete to provide better and healthy nutritional guidance to young athletes
Social Exchange and Sexual Behavior in Young Women's Premarital Relationships in Kenya
Luke, Nancy; Goldberg, Rachel E.; Mberu, Blessing U.; Zulu, Eliya M.
2011-01-01
Transactional sex, or the exchange of money and gifts for sexual activities within nonmarital relationships, has been widely considered a contributing factor to the disproportionate prevalence of HIV/AIDS among young women in sub-Saharan Africa. This study applied social exchange theory to premarital relationships in order to investigate the…
Young Learners' Response Processes When Taking Computerized Tasks for Speaking Assessment
Lee, Shinhye; Winke, Paula
2018-01-01
We investigated how young language learners process their responses on and perceive a computer-mediated, timed speaking test. Twenty 8-, 9-, and 10-year-old non-native English-speaking children (NNSs) and eight same-aged, native English-speaking children (NSs) completed seven computerized sample TOEFL® Primary™ speaking test tasks. We investigated…
Severe gonadotoxic insult manifests early in young girls treated for Ewing sarcoma
DEFF Research Database (Denmark)
Mörse, Helena; Elfving, Maria; Turkiewicz, Aleksandra
2016-01-01
We prospectively investigated anti-Müllerian hormone (AMH) as a measure of ovarian insult in young females during and after treatment for Wilms tumor (WT), osteosarcoma (OS), and Ewing sarcoma (ES).Twenty-one female childhood cancer patients, with a mean age of 7.9 years (range 0.6-17), entered...
Elke Zeijl; Marianne Beker; Koen Breedveld; Andries van den Broek; Jos de Haan; Lex Herweijer; Frank Huysmans; Karin Wittebrood
2003-01-01
Original title: Rapportage jeugd 2002. Policymakers have always devoted a lot of attention to the way in which young people spend their leisure time. More recently, they have increasingly pointed out that activities in the areas of sport, ICT or politics have a positive influence on young
Webb, Marianne Julie; Wadley, Greg; Sanci, Lena Amanda
2017-08-11
Despite experiencing a high prevalence and co-occurrence of mental health disorders and health-compromising behaviors, young people tend not to seek professional help for these concerns. However, they do regularly attend primary care, making primary care providers ideally situated to identify and discuss mental health and lifestyle issues as part of young people's routine health care. The aim was to investigate whether using a codesigned health and lifestyle-screening app, Check Up GP, in general practice influenced young people's assessment of the quality of their care (measures of patient-centered care and youth friendliness), and their disclosure of sensitive issues. In addition, this study aimed to explore young people's acceptance and experience of using a screening app during regular health care. This was a mixed methods implementation study of Check Up GP with young people aged 14 to 25 years attending a general practice clinic in urban Melbourne, Australia. A 1-month treatment-as-usual group was compared to a 2-month intervention group in which young people and their general practitioners (GPs) used Check Up GP. Young people in both groups completed an exit survey immediately after their consultation about disclosure, patient-centered and youth-friendly care, and judgment. In addition, participants in the intervention group were surveyed about app acceptability and usability and their willingness to use it again. Semistructured interviews with participants in the intervention group expanded on themes covered in the survey. The exit survey was completed by 30 young people in the treatment-as-usual group and 85 young people in the intervention group. Young people using Check Up GP reported greater disclosure of health issues (Ptime to ask questions. In all, 86% (73/85) of young people felt the app was a "good idea" and only 1% (1/85) thought it a "bad idea." Thematic analysis of qualitative interviews with 14 participants found that Check Up GP created scope