WorldWideScience

Sample records for bio-diesel initiatives potential

  1. Bio-diesel. Initiatives, potential and prospects in Thailand. A review

    International Nuclear Information System (INIS)

    Siriwardhana, Manjula; Opathella, G.K.C.; Jha, M.K.

    2009-01-01

    Thailand experiences a great economic and industrial development and is the second largest energy consumer in South East Asia. Being a net oil importer, Thai government has declared a renewable energy development programme in order to secure sustainable development and energy security. Thailand spends more than 10% of GDP for energy imports and transport sector accounts for 36% of total final energy consumption of which 50% is diesel. Diesel marks a huge impact on Thai economy. Thai government's bio-diesel development strategy is to replace 10% of petro-diesel in transport sector by bio-diesel by 2012. The plan is to increase the use of bio-diesel from 365 million liters in 2007 to 3100 million liters by 2012. This paper reviews the current status and potential of bio-diesel in Thailand and investigates and discusses the qualities and weaknesses of the proposed road-map. The proposed road-map definitely gives immediate solution for soaring oil prices, but the long-term economic, environmental and social impacts need to be examined. (author)

  2. Montana BioDiesel Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Peyton, Brent [Montana State Univ., Bozeman, MT (United States)

    2017-01-29

    This initiative funding helped put Montana State University (MSU) in a position to help lead in the development of biodiesel production strategies. Recent shortages in electrical power and rising gasoline prices have focused much attention on the development of alternative energy sources that will end our dependence on fossil fuels. In addition, as the concern for environmental impact of utilizing fossil fuels increases, effective strategies must be implemented to reduce emissions or the increased regulations imposed on fossil fuel production will cause economic barriers for their use to continue to increase. Biodiesel has been repeatedly promoted as a more environmentally sound and renewable source of fuel and may prove to be a highly viable solution to provide, at the least, a proportion of our energy needs. Currently there are both practical and economic barriers to the implementation of alternative energy however the advent of these technologies is inevitable. Since many of the same strategies for the storage, transport, and utilization of biodiesel are common with that of fossil fuels, the practical barriers for biodiesel are comparatively minimal. Strategies were developed to harness the CO2 as feedstock to support the growth of biodiesel producing algae. The initiative funding led to the successful funding of highly rated projects in competitive national grant programs in the National Science Foundation and the Department of Energy. This funding put MSU in a key position to develop technologies to utilize the CO2 rich emissions produced in fossil fuel utilization and assembled world experts concerning the growth characteristics of photosynthetic microorganisms capable of producing biodiesel.

  3. Bio diesel production from algae

    International Nuclear Information System (INIS)

    Khola, G.; Ghazala, B.

    2011-01-01

    Algae appear to be an emerging source of biomass for bio diesel that has the potential to completely displace fossil fuel. Two thirds of earth's surface is covered with water, thus alga e would truly be renewable option of great potential for global energy needs. This study discusses specific and comparative bio diesel quantitative potential of Cladophora sp., also highlighting its biomass (after oil extraction), pH and sediments (glycerine, water and pigments) quantitative properties. Comparison of Cladophora sp., with Oedogonium sp., and Spirogyra sp., (Hossain et al., 2008) shows that Cladophora sp., produce higher quantity of bio diesel than Spirogyra sp., whereas biomass and sediments were higher than the both algal specimens in comparison to the results obtained by earlier workers. No prominent difference in pH of bio diesel was found. In Pakistan this is a first step towards bio diesel production from algae. Results indicate that Cladophora sp., provide a reasonable quantity of bio diesel, its greater biomass after oil extraction and sediments make it a better option for bio diesel production than the comparing species. (author)

  4. Bio diesel energy potential in the Republic of Macedonia, v. 14(55)

    International Nuclear Information System (INIS)

    Armenski, Slave; Davkova, Katitsa

    2006-01-01

    Bio diesel ia a liquid fuel produced from raw vegetable oil, animal fats and cooking oils and can be used like substitute or addition of petroleum diesel. Bio diesel is alternative fuel and can be use in diesel engines, to obtain power similar lake petroleum diesel. During his combustion it realises small quantities of carbon dioxide and sulfur oxides. In this paper is carrying out an investigation of the sources of raw vegetables oils on the quantities which are produced from agriculture and livestock in the R. of Macedonia, in the term of their quantities estimation, bio diesel quantity estimation and energy value estimation. For this reason it is analyzed used arable area, as well as available free pasture area with: soybean, rapes sed, sun-flower and other vegetable oil plants. By defined areas and average quantities production in the past five years (1997-2001), it is determined the whole raw vegetable oil quantities from source of row material. In the area of livestock in this paper is defined the number of animal and poultry slaughtered and the quantity of waste fats. In the base of determined quantities from row vegetable oils, used cooking oils and restaurant frying oils and waste animal fats, it is determined mass and energy quantities of bio diesel which can be produced in the R. of Macedonia. (Author)

  5. Bio diesel energy potential in the Republic of Macedonia, v. 15(56)

    International Nuclear Information System (INIS)

    Armenski, Slave; Davkova, Katitsa

    2007-01-01

    Bio diesel ia a liquid fuel produced from raw vegetable oil, animal fats and cooking oils and can be used like substitute or addition of petroleum diesel. Bio diesel is alternative fuel and can be use in diesel engines, to obtain power similar lake petroleum diesel. During his combustion it realises small quantities of carbon dioxide and sulfur oxides. In this paper is carrying out an investigation of the sources of raw vegetables oils on the quantities which are produced from agriculture and livestock in the R. of Macedonia, in the term of their quantities estimation, bio diesel quantity estimation and energy value estimation. For this reason it is analyzed used arable area, as well as available free pasture area with: soybean, rapes sed, sun-flower and other vegetable oil plants. By defined areas and average quantities production in the past five years (1997-2001), it is determined the whole raw vegetable oil quantities from source of row material. In the area of livestock in this paper is defined the number of animal and poultry slaughtered and the quantity of waste fats. In the base of determined quantities from row vegetable oils, used cooking oils and restaurant frying oils and waste animal fats, it is determined mass and energy quantities of bio diesel which can be produced in the R. of Macedonia. (Author)

  6. Bio-diesel: A candidate for a Nigeria energy mix

    International Nuclear Information System (INIS)

    Eze, T.; Dim, L. A.; Funtua, I. I.; Oladipo, M. O. A.

    2011-01-01

    This paper presents a review of bio-diesel development and economic potentials. The basics of biodiesel and its production technology are described. Attention is given to development potential, challenges and prospests of bio-diesel in Nigeria with ground facts on bio-diesel production feasibility in Nigeria highlighted.

  7. Potential of waste frying oil as a feedstock for the production of bio-diesel

    Energy Technology Data Exchange (ETDEWEB)

    Quadri, Syed M Raza [Dept. of Chemical Engineering, Z.H.C.E.T, A.M.U, Aligarh (India)], e-mail: chemicalraza@gmail.com; Wani, Omar Bashir; Athar, Moina [Dept. of Petroleum Studies, Z.H.C.E.T, A.M.U, Aligarh (India)

    2012-11-01

    To face the challenges of climbing Petroleum demand and of climate changes related to Carbon dioxide emissions, interest grows in sustainable fuels made from organic matter. World production of bio fuels has experienced phenomenal growth. The search for alternatives to petroleum based fuel has led to the development of fuels from various renewable sources, including feed stocks, such as fats and oils. Several kinds of fuels can be derived from these feed stocks. One of them is biodiesel, which is mono alkyl esters of vegetables oils and animal fats and produced by transesterification of oil and fats with alcohols in the presence of acid, alkali or enzyme base catalysts. The main hurdle in using the biodiesel is its cost which is mainly the cost of virgin oil. In India every year Millions of liters of waste frying oil are discarded into the sewage system which adds cost to its treatment and add up to the pollution of ground water. This paper proposed the production of Bio-diesel from the very same waste frying oil. The production of Bio-diesel from this waste frying oil offers economic, social, environmental and health benefits. The Bio-diesel produced finds the same use as the conventional diesel but this happens to be cost effective.

  8. Jatropha bio-diesel production and use

    Energy Technology Data Exchange (ETDEWEB)

    Achten, W.M.J.; Aerts, R.; Muys, B. [Katholieke Universiteit Leuven, Division Forest, Nature and Landscape, Celestijnenlaan 200 E Box 2411, BE-3001 Leuven (Belgium); Verchot, L. [World Agroforestry Centre (ICRAF) Head Quarters, United Nations Avenue, P.O. Box 30677, Nairobi (Kenya); Franken, Y.J. [FACT Foundation, Horsten 1, 5612 AX Eindhoven (Netherlands); Mathijs, E. [Katholieke Universiteit Leuven, Division Agricultural and Food Economics, Willem de Croylaan 42 Box 2424, BE-3001 Leuven (Belgium); Singh, V.P. [World Agroforestry Centre (ICRAF) Regional Office for South Asia, CG Block, 1st Floor, National Agricultural Science Centre, Dev Prakash Shastri Marg, Pusa, New Delhi 110 012 (India)

    2008-12-15

    The interest in using Jatropha curcas L. (JCL) as a feedstock for the production of bio-diesel is rapidly growing. The properties of the crop and its oil have persuaded investors, policy makers and clean development mechanism (CDM) project developers to consider JCL as a substitute for fossil fuels to reduce greenhouse gas emissions. However, JCL is still a wild plant of which basic agronomic properties are not thoroughly understood and the environmental effects have not been investigated yet. Gray literature reports are very optimistic on simultaneous wasteland reclamation capability and oil yields, further fueling the Jatropha bio-diesel hype. In this paper, we give an overview of the currently available information on the different process steps of the production process of bio-diesel from JCL, being cultivation and production of seeds, extraction of the oil, conversion to and the use of the bio-diesel and the by-products. Based on this collection of data and information the best available practice, the shortcomings and the potential environmental risks and benefits are discussed for each production step. The review concludes with a call for general precaution and for science to be applied. (author)

  9. Jatropha bio-diesel production and use

    International Nuclear Information System (INIS)

    Achten, W.M.J.; Aerts, R.; Muys, B.; Verchot, L.; Franken, Y.J.; Mathijs, E.; Singh, V.P.

    2008-01-01

    The interest in using Jatropha curcas L. (JCL) as a feedstock for the production of bio-diesel is rapidly growing. The properties of the crop and its oil have persuaded investors, policy makers and clean development mechanism (CDM) project developers to consider JCL as a substitute for fossil fuels to reduce greenhouse gas emissions. However, JCL is still a wild plant of which basic agronomic properties are not thoroughly understood and the environmental effects have not been investigated yet. Gray literature reports are very optimistic on simultaneous wasteland reclamation capability and oil yields, further fueling the Jatropha bio-diesel hype. In this paper, we give an overview of the currently available information on the different process steps of the production process of bio-diesel from JCL, being cultivation and production of seeds, extraction of the oil, conversion to and the use of the bio-diesel and the by-products. Based on this collection of data and information the best available practice, the shortcomings and the potential environmental risks and benefits are discussed for each production step. The review concludes with a call for general precaution and for science to be applied. (author)

  10. Evaluation of Emissions Bio diesel

    International Nuclear Information System (INIS)

    Rodriguez Maroto, J. J.; Dorronsoro Arenal, J. L.; Rojas Garcia, E.; Perez Pastor, R.; Garcia Alonso, S.

    2007-01-01

    The generation of energy from vegetal products is one of the possibilities to our reach in order to reduce the atmospheric pollution. Particularly, the use of bio diesel in internal combustion engines can be one of the best options. The finest particles emitted by the combustion engines are easily breathable and on them different substances can be absorbed presumably toxic, between which it is possible to emphasize the polycyclic aromatic hydrocarbons (PAHs), by its demonstrated carcinogen character. In this work, it is studied on the one hand, the characteristics that can present the aerosol of emission in a diesel engine with a maximum power of 97 kW, working without load to 600 rpm, using as combustible mixtures of bio diesel and diesel in different proportions. On the other hand, the evolution that takes place in the concentration of PAHs in emission particles, according to the percentage of bio diesel used in the combustible mixture. (Author) 9 refs

  11. Evaluation of Emissions Bio diesel

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez Maroto, J J; Dorronsoro Arenal, J L; Rojas Garcia, E; Perez Pastor, R; Garcia Alonso, S

    2007-09-27

    The generation of energy from vegetal products is one of the possibilities to our reach in order to reduce the atmospheric pollution. Particularly, the use of bio diesel in internal combustion engines can be one of the best options. The finest particles emitted by the combustion engines are easily breathable and on them different substances can be absorbed presumably toxic, between which it is possible to emphasize the polycyclic aromatic hydrocarbons (PAHs), by its demonstrated carcinogen character. In this work, it is studied on the one hand, the characteristics that can present the aerosol of emission in a diesel engine with a maximum power of 97 kW, working without load to 600 rpm, using as combustible mixtures of bio diesel and diesel in different proportions. On the other hand, the evolution that takes place in the concentration of PAHs in emission particles, according to the percentage of bio diesel used in the combustible mixture. (Author) 9 refs.

  12. Feasibility study of utilizing jatropha curcas oil as bio-diesel in an oil firing burner system

    Science.gov (United States)

    Shaiful, A. I. M.; Jaafar, M. N. Mohd; Sahar, A. M.

    2017-09-01

    Jatropha oil derived from the Jatropha Curcas Linnaeus is one of the high potential plants to be use as bio-diesel. The purpose of this research is to carry out a feasibility study of using jatropha oil as bio-diesel on oil firing burner system. Like other bio-diesels, jatropha oil can also be used in any combustion engine and the performance and emissions such as NOx, SO2, CO and CO2 as well as unburned hydocarbon (UHC) from the engine will vary depending on the bio-diesel blends. The properties of Conventional Diesel Fuel (CDF) obtained will be used as baseline and the jatropha oil properties will be compared as well as other bio-diesels. From several researches, the properties of jatropha oil was found to be quite similar with other bio-diesel such as palm oil, neem, keranja and pongamia bio-diesel and complying with the ASTM standard for bio-diesel. Still, there are factors and issues concerning the use of jatropha oil such as technology, economy, legislation and resource. Plus, there several challenges to the growth of bio-diesel industry development since the world right now do not totally depend on the bio-diesel.

  13. Bio diesel, v. 15(58)

    International Nuclear Information System (INIS)

    Gicheva, Ljubitsa

    2007-01-01

    The history of bio-fuels/bio-diesel is more political and economical than it is technological. The technology of the production is the same as it was 200 years ago. The economy closed the usage of bio-fuels in the middies of the 20 Th century and put it back on the agenda of the world economy at the beginning of the 21 st century. With price of more then 70 US$ per barrel of grudge oil, production and usage of bio-fuels becomes more economical category rather than political and ecological. If we, additionally, add secondary, yet nowadays very important factors, as ecological protection, recycling the emission of poisonous gasses, exploitation of agro sector, then the reincarnation of bio-fuels is very interesting, and for Macedonia a potentially strategic category. The basics of the biography is to follow in the article paying special attention on the characteristics, standards, production, processing and usage of the bio-diesel fuel as well as the blended B20 and B5. (Author)

  14. Bio diesel, v. 15(59)

    International Nuclear Information System (INIS)

    Gicheva, Ljubitsa

    2007-01-01

    The history of bio-fuels/bio-diesel is more political and economical than it is technological. The technology of the production is the same as it was 200 years ago. The economy closed the usage of bio-fuels in the middies of the 20 Th century and put it back on the agenda of the world economy at the beginning of the 21 st century. With price of more then 70 US$ per barrel of grudge oil, production and usage of bio-fuels becomes more economical category rather than political and ecological. If we, additionally, add secondary, yet nowadays very important factors, as ecological protection, recycling the emission of poisonous gasses, exploitation of agro sector, then the reincarnation of bio-fuels is very interesting, and for Macedonia a potentially strategic category. The basics of the biography is to follow in the article paying special attention on the characteristics, standards, production, processing and usage of the bio-diesel fuel as well as the blended B20 and B5. (Author)

  15. MICRO ALGAE CULTURE FROM RAWA GAMBUT: INTRODUCTION STUDY OF MICRO ALGAE POTENTIAL AS BIO DIESEL RAW MATERIAL

    Directory of Open Access Journals (Sweden)

    Dewi Jumiarni

    2018-01-01

    Full Text Available Sustainable production of renewable energy is being a crucial problem, since fuel demand in Indonesia rises annually while the production decreases. Microalgae have been suggested as a potential feedstock for biofuel production. This research was a preliminary study to identified microalgal culture from water of peat swamp, and probe its potential as biodiesel feedstock.  Microalgal identification was conducted by morphological observation using microscope, while potential as biodiesel was probed by detection using Nile Red staining and supported by literature study. This research has identified 19 species of microalgae from culture, which were consisting of 16 species were Chlorophyceae and 3 species were Bacillariophyceae. Microalgae that  potentially to be developed biodiesel feedstock were Cyclotella atomus, Cyclotella sp, Nitzschia sp, Chlorella sp, Desmodesmus sp, Chlorella ellipsoida and Chlorella vulgaris.

  16. Bintangor Laut (Calophylum Inophylum L.) Oil: A promising source of bio diesel

    International Nuclear Information System (INIS)

    Shaharuddin, H.; Wan Asma, I.; Rafidah, J.; Puad, E.; Mahanim, S.

    2010-01-01

    Full text: Bintangor Laut (BL) oil is non-edible oil extracted from the seeds of Calophylum Inophylum L. It is a tree of 12-20 m height, with spread branches. The BL tree grows along coastal areas and adjacent lowland forests, although it occasionally occurs inland at higher elevations and it is native to east Africa, India, Southeast Asia, Australia, and the South Pacific. This study investigates the potential of BL oil as an alternative source of bio energy (bio diesel). The average oil content of BL seeds is 35% by weight. Fuel properties of trans esterified BL oil chemically known as methyl esters (bio diesel) were compared with bio diesel standards of American Standard Testing Method (ASTM). The fuel properties of BL bio diesel (100%) that is specific gravity is 0.92, kinematic viscosity at 40 degree Celsius, 7.43, flash point 151 degree Celsius, pour point -4 degree Celsius, cloud point 4 degree Celsius, B10 were very close to petroleum diesel. On the basis of these fuel properties, it is concluded that BL bio diesel is a good option for renewable energy to reduce dependency on import of foreign oil. (author)

  17. Life Cycle Assessment of Bio-diesel Production—A Comparative Analysis

    Science.gov (United States)

    Chatterjee, R.; Sharma, V.; Mukherjee, S.; Kumar, S.

    2014-04-01

    This work deals with the comparative analysis of environmental impacts of bio-diesel produced from Jatropha curcas, Rapeseed and Palm oil by applying the life cycle assessment and eco-efficiency concepts. The environmental impact indicators considered in the present paper include global warming potential (GWP, CO2 equivalent), acidification potential (AP, SO2 equivalent) and eutrophication potential (EP, NO3 equivalent). Different weighting techniques have been used to present and evaluate the environmental characteristics of bio-diesel. With the assistance of normalization values, the eco-efficiency was demonstrated in this work. The results indicate that the energy consumption of bio-diesel production is lowest in Jatropha while AP and EP are more in case of Jatropha than that of Rapeseed and Palm oil.

  18. Bio diesel- the Clean, Green Fuel for Diesel Engines

    International Nuclear Information System (INIS)

    Elkareish, S.M.M.

    2004-01-01

    Natural, renewable resources such as vegetable oils, animal fats and recycled restaurant greases can be chemically transformed into clean burning bio diesel fuels (1). Just like petroleum diesel, bio diesel operates in combustion-ignition engines. Blends of up to 20% bio diesel (mixed with petroleum diesel fuels) can be used in nearly all diesel equipment and are compatible with most storage and distribution equipment. Using bio diesel in a conventional diesel engine substantially reduces emissions of unburned hydrocarbons, carbon monoxide, sulphates, polycyclic aromatic hydrocarbons, nitrated polycyclic aromatic hydrocarbons, and particulate matter. The use of bio diesel has grown dramatically during the last few years. Egypt has a promising experiment in promoting forestation by cultivation of Jatropha plant especially in luxor and many other sites of the country. The first production of the Egyptian Jatropha seeds oil is now under evaluation to produce a cost-competitive bio diesel fuel

  19. Development of production technology for bio diesel fuel and feasibility test of bio diesel engine (II)

    Energy Technology Data Exchange (ETDEWEB)

    Na, Y J; Ju, U S; Park, Y C [National Kyung Sang University (Korea, Republic of)

    1996-02-01

    At the beginning of the 21 st century two urgent tasks which our global countries would face with could be the security of the alternative energy source as a preparation against the fossil energy exhaustion and the development of the clean energy source to protect the environment from pollution. The above two problems should be solved together. The bio diesel oil which is made by methylesterfication of bio oil has very low sulfur content than does the diesel oil. Therefore, there is a great possibility to solve the pollution problem caused by the exhaust gas from diesel engine vehicles. So, bio oil has been attracted with attentions as an alternative and clean energy source. Advanced countries began early to develop the bio diesel oil suitable to their respective conditions. Recently their production stage have reached to the commercial level partially. The sudden increase of energy demand followed by a rapid growth of industry and the serious situation about the environmental pollution caused by the exhaust has from diesel engine vehicles occupying 42% of distribution among all vehicles have called attention of our government to consider the importance of alternative and clean energy sources for the future on the national scale. This study is consisted of three main parts; - The development of production technology for bio diesel oil. - The development of the atomization improvement method and nozzle for high viscous vegetable oils. - Feasibility test of bio diesel engine. (author) 119 refs., 52 tabs., 88 figs.

  20. On the potential of absorption and reactive adsorption for desulfurization of ultra low-sulfur commercial diesel in the liquid phase in the presence of fuel additive and bio-diesel

    Energy Technology Data Exchange (ETDEWEB)

    Pieterse, J.A.Z.; Van Eijk, S.; Van Dijk, H.A.J.; Van den Brink, R.W. [Energy research Center of the Netherlands, P.O. Box 1, 1755 ZG Petten (Netherlands)

    2011-03-15

    Sorption of sulfur components in the liquid phase was used to desulfurize ultra low sulfur diesel (ULSD) to below 1 ppmw S. Several concepts of sorption were considered by using both physisorption and chemisorption materials and conditions. Adsorption assisted by reaction with Ni sorbent was found to be most successful. Using a pre-commercial diesel representing a mature diesel on all aspects except for the absence of fuel stabilizers and bio-diesel, a sulfur breakthrough capacity of 2 mg S/g could be achieved using a Ni-sorbent at an acceptable LHSV of 0.7 h{sup -1} on average. However, successive experiments indicated that the desulfurization capacity depended strongly on the presence of fuel-additive and bio-diesel in commercial ULSD. The presence of the cetane improver 2-ethylhexylnitrate (2EHN) was shown to decrease the sulfur capacity by roughly 50%. The presence of bio-diesel (fatty acid methyl ester, abbreviated to FAME) was shown to completely disable the desulfurization process. This was confirmed by comparing BP Ultimate diesel with FAME (obtained in 2008) and without FAME (obtained in 2006). From this evaluation it turned out that the targeted breakthrough capacity of 1 mg S/g sorbent was within reach for commercial ULSD until late 2006 when adding bio-diesel to ULSD became common practice in Europe. Several attempts to remove the additives prior to desulfurization by using copper loaded zeolites, active carbon and silica gel proved unsuccessful to bring the sulfur adsorption capacity for current diesel to the level observed for 2EHN and FAME-free diesel. It is concluded that sorption in the liquid phase does not yet represent a viable desulfurization technology for ultra-low sulfur diesel.

  1. Bio-diesel fuels production: Feasibility studies

    International Nuclear Information System (INIS)

    Tabasso, L.

    1993-01-01

    This paper reviews the efforts being made by Italy's national government and private industry to develop diesel engine fuels derived from vegetable oils, in particular, sunflower seed oil. These fuels are being promoted in Italy from the environmental protection stand-point in that they don't contain any sulfur, the main cause of acid rain, and from the agricultural stand-point in that they provide Italian farmers, whose food crop production capacity is limited due to European Communities agreements, with the opportunity to use their set-aside land for the production of energy crops. This paper provides brief notes on the key performance characteristics of bio-diesel fuels, whose application doesn't require any modifications to diesel engines, apart from minor adjustments to the air/fuel mix regulating system, and assesses commercialization prospects. Brief mention is made of the problems being encountered by the Government in the establishing fair bio-fuel production tax rebates which are compatible with the marketing practices of the petroleum industry. One of the strategies being considered is to use the bio-fuels as additives to be mixed with conventional fuel oils so as to derive a fuel which meets the new European air pollution standards

  2. French bio-diesel demand and promoting measures analysis by 2010

    International Nuclear Information System (INIS)

    Bernard, F.

    2008-02-01

    The researches presented aim at assessing bio-diesel promoting measures under consideration in France by 2010. This assessment is based on a deep study of French bio-diesel demand. The use of a linear model for optimizing the whole French refining industry costs allow us to take into account the physicochemical characteristics of bio-diesel useful for gas oil blending operation. This researches show that bio-diesel can be incorporated up to 27% blend in volume to diesel fuel without major technical problem. A decomposition of the value allotted to the bio-diesel by French refiners according to its physicochemical characteristics shows that energy content is the most disadvantageous characteristics for bio-diesel incorporation and, up to 17%, density become also constraining. However, the low bio-diesel sulphur content could become interesting from now to 2010. On the basis of this bio-diesel demand analysis, we proceed to an external coupling of an agro-industrial model of bio-diesel supply with the French refining model. Thus, we study the impact of the 2010 French bio-diesel consumption objective on agricultural surface need, the competitiveness of the bio-diesel, the reduction of greenhouse gases emissions and the trade balance of the petroleum products. On this basis, we propose a critical analysis of French bio-diesel promoting measures under consideration by 2010. (author)

  3. Production of bio diesel from chicken frying oil

    International Nuclear Information System (INIS)

    Bakir, E.T.; Fadhil, A.B.

    2011-01-01

    Chicken fried oil was converted into different bio diesels through single step transesterification and two step transesterification, namely acid-base and base-base catalyzed transesterification. Hydrochloric acid and potassium hydroxide with methanol were used for this purpose. The results showed that two step base catalyzed transesterification was better compared to other methods. It resulted in higher yield and better fuel properties. Transesterification of fried chicken oil was monitored by TLC technique and compared with that of the parent oil. Fuel properties of the products have been measured and found markedly enhanced compared to those of the parent oil. Also, the values satisfied the standard limits according to the ASTM standards. Blending of the better bio diesel sample with petro diesel was made using three volume percentages (10, 30 and 50% v/v). The results disclosed that blending had slight effect on the original properties of petro diesel.

  4. Environmental cost-effectiveness of bio diesel production in Greece: Current policies and alternative scenarios

    International Nuclear Information System (INIS)

    Iliopoulos, Constantine; Rozakis, Stelios

    2010-01-01

    Following European Directive 2003/30/EC, the Greek Government adapted legislation that introduces and regulates the bio diesel market. The implemented quota scheme allocates the country's annual, predetermined, tax exempt production of bio diesel to industries based on their ability to meet several criteria. A number of bio diesel supply chain stakeholders have criticized this policy for being efficiency-robbing and vague. This paper uses 2007 data from energy crop farms and three bio diesel-producing companies in order to assess these criticisms. We study the economic and environmental aspects of the currently adopted policy and compare them to three alternative scenarios. We conclude that such criticisms have a merit and that policy makers need to reconsider their alternative options regarding the promotion of bio diesel in transport. Permission of sales directly to local consumers and promotion of forward integration by farmers are efficiency enhancing and environment-friendly means of promoting the use of bio diesel in transport.

  5. Determining waste lipids stability and possible effects in bio diesel production

    International Nuclear Information System (INIS)

    Azocar, L.; Ciudad, G.; Navia, R.

    2009-01-01

    Waste lipids are a sustainable raw material alternative for bio diesel production, avoiding excessive use of agricultural soil. However, this raw material can be degraded in a short time of storage, affecting bio diesel production process and quality. The aim of this work was to investigate the possible degradation of waste frying oil (WFO) and animal fat (AF), monitoring parameters that could affect the bio diesel quality. (Author)

  6. Bio diesel synthesis from pongamia pinnata oil over modified CeO2 catalysts

    International Nuclear Information System (INIS)

    Venkatesh; Sathgatta Z, M. S.; Manjunatha, S.; Thammannigowda V, V.

    2014-01-01

    This study investigates the use of CeO 2 , ZrO 2 , Mg O and CeO 2 -ZrO 2 , CeO 2 -Mg O, CeO 2 -ZrO 2 -Mg O mixed oxides as solid base catalysts for the transesterification of Pongamia pinnata oil with methanol to produce bio diesel. SO 4 2- /CeO 2 and SO 4 2- /CeO 2 -ZrO 2 were also prepared and used as solid acid catalysts for esterification of Pongamia pinnata oil (P-oil) to reduce the % of free fatty acid (FFA) in P-oil. The oxide catalysts were prepared by an incipient wetness impregnation method and characterized by techniques such as NH 3 -Tpd for surface acidity, CO 2 -Tpd for surface basicity and powder X-ray diffraction for crystallinity. The effect of nature of the catalyst, methanol to P-oil molar ratio and reaction time in esterification as well as in transesterification was investigated. The catalytic materials were reactive d and reused for five reaction cycles and the results showed that the ceria based catalysts have reasonably good reusability both in esterification and transesterification reaction. The test results also revealed that the CeO 2 -ZrO 2 modified with Mg O could have potential for use in the large scale bio diesel production. (Author)

  7. Bio Diesel Cellulosic Ethanol Research Project

    Energy Technology Data Exchange (ETDEWEB)

    Hanlon, Edward A. [County of Hendry, FL (United States); Capece, John C. [County of Hendry, FL (United States); McAvoy, Eugene [County of Hendry, FL (United States); Hodges, Alan Wayne [County of Hendry, FL (United States); Shukla, Sanjay [County of Hendry, FL (United States); Ozores-Hamilton, Monica [County of Hendry, FL (United States); Gilbert, Rob [County of Hendry, FL (United States); Wright, Alan [County of Hendry, FL (United States); Baucum, L. [County of Hendry, FL (United States)

    2017-02-07

    The objective of the project is to create the Hendry County Sustainable Biofuels Center and initiate its research, development, and education programs. The mission is to develop engineering and economic assessment methods to evaluate the natural resources impacts of biomass farming and fuel conversion systems; provide sustainability assessments of specific biofuels productions proposals; develop biomass farming and fuel conversion systems that are compatible with south Florida ecosystem restoration priorities; create ecosystem services opportunities and structures to diversify farm income; monitor the range of research and development activities necessary to the creation of sutstainable biofuels production systems in south Florida, identify gaps in the regional research, and assist in the development and coordination of additional projects to fill out the required knowledge base; prepare the workforce of southwest Florida for employment in biofuels related professions; and assist businesses & governmental design and realize sustainable biofuels projects.

  8. Bio diesel synthesis from pongamia pinnata oil over modified CeO{sub 2} catalysts

    Energy Technology Data Exchange (ETDEWEB)

    Venkatesh; Sathgatta Z, M. S.; Manjunatha, S.; Thammannigowda V, V., E-mail: mohamed.shamshuddin@gmail.com [HMS Institute of Technology, Chemistry Research Laboratory, NH4, Kyathsandra, Tumkur, 572104 Karnataka (India)

    2014-07-01

    This study investigates the use of CeO{sub 2}, ZrO{sub 2}, Mg O and CeO{sub 2}-ZrO{sub 2}, CeO{sub 2}-Mg O, CeO{sub 2}-ZrO{sub 2}-Mg O mixed oxides as solid base catalysts for the transesterification of Pongamia pinnata oil with methanol to produce bio diesel. SO{sub 4}{sup 2-}/CeO{sub 2} and SO{sub 4}{sup 2-}/CeO{sub 2}-ZrO{sub 2} were also prepared and used as solid acid catalysts for esterification of Pongamia pinnata oil (P-oil) to reduce the % of free fatty acid (FFA) in P-oil. The oxide catalysts were prepared by an incipient wetness impregnation method and characterized by techniques such as NH{sub 3}-Tpd for surface acidity, CO{sub 2}-Tpd for surface basicity and powder X-ray diffraction for crystallinity. The effect of nature of the catalyst, methanol to P-oil molar ratio and reaction time in esterification as well as in transesterification was investigated. The catalytic materials were reactive d and reused for five reaction cycles and the results showed that the ceria based catalysts have reasonably good reusability both in esterification and transesterification reaction. The test results also revealed that the CeO{sub 2}-ZrO{sub 2} modified with Mg O could have potential for use in the large scale bio diesel production. (Author)

  9. Preliminary detection of native lipase producing microorganisms for bio diesel production

    International Nuclear Information System (INIS)

    Ciudad, G.; Jorquera, M.; Briones, R.; Azocar, L.; Leal, J.; Navia, R.

    2009-01-01

    Lipase producing microorganisms (LPM) may catalyze the hydrolysis or transesterification of triacylglycerols to alkyl esters of fatty acids (bio diesel). The main objective of this work was to detect LPM in oil and grease contaminated environments for future applications in bio diesel production from rapeseed oil. Samples from contaminated soil (with rapeseed oil) from an industrial facility and contaminated soil (with salmon grease) near to a fish wastewater treatment plant were collected. (Author)

  10. Preliminary detection of native lipase producing microorganisms for bio diesel production

    Energy Technology Data Exchange (ETDEWEB)

    Ciudad, G.; Jorquera, M.; Briones, R.; Azocar, L.; Leal, J.; Navia, R.

    2009-07-01

    Lipase producing microorganisms (LPM) may catalyze the hydrolysis or transesterification of triacylglycerols to alkyl esters of fatty acids (bio diesel). The main objective of this work was to detect LPM in oil and grease contaminated environments for future applications in bio diesel production from rapeseed oil. Samples from contaminated soil (with rapeseed oil) from an industrial facility and contaminated soil (with salmon grease) near to a fish wastewater treatment plant were collected. (Author)

  11. Emission testing of jatropha and pongamia mixed bio diesel fuel in a diesel engine

    International Nuclear Information System (INIS)

    Ali, M.; Shaikh, A.A.

    2012-01-01

    The present investigation is based on the emission characteristics of mixed bio diesel fuel in a four stroke single cylinder compression ignition engine at constant speed. Refined oils of jatropha and pongamia are converted into bio diesel by acid catalyzed esterification and base catalyzed transesterification reactions. The jatropha and pongamia bio diesel were mixed in equal proportions with conventional mineral diesel fuel. Four samples of fuel were tested namely, diesel fuel, B10, B20 and B40. The emission analysis showed B20 mixed bio diesel fuel blend having better results as compared to other samples. There is 60% and 35% lower emission of carbon monoxide and in sulphur dioxide observed while consuming B20 blended fuel respectively. The test result showed NOx emissions were 10% higher from bio diesel fuel, as compared to conventional diesel fuel. However, these emissions may be reduced by EGR (Exhaust Gas Recirculation) technology. Present research also revealed that that B20 mixed bio diesel fuel can be used, without any modification in a CI engine. (author)

  12. A techno-economic evaluation of two non-edible vegetable oil based bio diesel in Pakistan

    International Nuclear Information System (INIS)

    Chakrabarti, M.H.; Ali, M.

    2010-01-01

    Technical evaluation of Bio diesel, produced from various non-edible oils, was carried out on the basis of emission profile, torque, engine brake power and exhaust temperatures at 10% blend ratio (by volume) with mineral diesel. The performance of engine parameters showed that the castor oil based bio diesel gave the best results. Economic feasibility for bio diesel production was carried out based on available data on cultivation of necessary plants on marginal lands. This economic analysis also included the value of by-products which would be available during the chemical process for the production of bio diesel. It was found that jatropha bio diesel could be produced at a comparable cost to mineral diesel, however, castor bio diesel required substantial subsidies or mass cultivation of plants on marginal lands to enable it to compete economically with mineral diesel. (author)

  13. Existing landraces of Jatropha Curcas L. (physic nut) in Nepal and analysis of their bio-diesel content

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Ram Prasad

    2010-09-15

    The aim of this work was to find the existing landraces of Jatropha curcas in different agro ecological regions of Nepal and their Bio-Diesel content. More specifically, research efforts focused on (1) existing landraces (varieties) in all three topographic regions of Nepal (2) Bio-diesel content in those varieties (3) Bio-Diesel content in varieties from Laos (4) Constraints faced by the Nepalese Jatropha grower (5) Compare the quality of Bio-diesel between the Nepalese varieties and Laos varieties. To collect all the information, Seeds were collected from Nepal (Terai: Chitwan; Hill: Palpa and Syanja; Mountain: Tanahu and Gorkha) and Vientiane province from Laos.

  14. [Particle emission characteristics of diesel bus fueled with bio-diesel].

    Science.gov (United States)

    Lou, Di-Ming; Chen, Feng; Hu, Zhi-Yuan; Tan, Pi-Qiang; Hu, Wei

    2013-10-01

    With the use of the Engine Exhaust Particle Sizer (EEPS), a study on the characteristics of particle emissions was carried out on a China-IV diesel bus fueled with blends of 5% , 10% , 20% , 50% bio-diesel transformed from restaurant waste oil and China-IV diesel (marked separately by BD5, BD10, BD20, BD50), pure bio-diesel (BD100) and pure diesel (BD0). The results indicated that particulate number (PN) and mass (PM) emissions of bio-diesel blends increased with the increase in bus speed and acceleration; with increasing bio-diesel content, particulate emissions displayed a relevant declining trend. In different speed ranges, the size distribution of particulate number emissions (PNSD) was bimodal; in different acceleration ranges, PNSD showed a gradual transition from bimodal shape to unimodal when bus operation was switched from decelerating to accelerating status. Bio-diesel blends with higher mixture ratios showed significant reduction in PN emissions for accumulated modes, and the particulate number emission peaks moved towards smaller sizes; but little change was obtained in PN emissions for nuclei modes; reduction also occurred in particle geometric diameter (Dg).

  15. Effect of raw material on physical properties and yield of bio diesel

    International Nuclear Information System (INIS)

    Malik, S.R.; Khan, J.R.

    2008-01-01

    Production of bio diesel via trans-esterification method is under investigation as an alternative fuel. The prospects of using crude vegetable oil have not been investigated extensively which may be due to economic reasons. Used and unused vegetable oils have been considered for this purpose and a series of experimental results were reported. This study encircles similar prospect and compares the results. Various samples of refined and crude forms of Canola and Cottonseed Oils were tested. Viscosity, densities. Pour point, cloud point and yield of bio-diesels have been determined which may provide a useful data for further investigations. (author)

  16. Methyl Ester (Bio diesel) Production from Waste Cooking Vegetable Oil by Microwave Irradiation

    International Nuclear Information System (INIS)

    Khatun, M.S.; Khatun, M.A.; Khan, M.Z.H.; Debnath, M.

    2014-01-01

    In this study we tried to develop, test and optimize a batch microwave system using waste cooking vegetable oil (WCVO) that was used as bio diesel feedstock. Two catalysts, sodium hydroxide (NaOH) and potassium hydroxide (KOH) were tested in this study. Transesterification reactions between oil and methanol were carried out in presence of microwaves. It was observed that by using of microwaves, the reaction times were drastically reduced. As high as 99.5 % conversions could be achieved for 0.5% KOH concentration. Moreover, quality analysis of bio diesels according to international standards was performed and the samples were found to meet the necessary specifications. (author)

  17. French bio-diesel demand and promoting measures analysis by 2010; Analyse de la demande et des mesures de promotion francaises du biodiesel a l'horizon 2010

    Energy Technology Data Exchange (ETDEWEB)

    Bernard, F

    2008-02-15

    The researches presented aim at assessing bio-diesel promoting measures under consideration in France by 2010. This assessment is based on a deep study of French bio-diesel demand. The use of a linear model for optimizing the whole French refining industry costs allow us to take into account the physicochemical characteristics of bio-diesel useful for gas oil blending operation. This researches show that bio-diesel can be incorporated up to 27% blend in volume to diesel fuel without major technical problem. A decomposition of the value allotted to the bio-diesel by French refiners according to its physicochemical characteristics shows that energy content is the most disadvantageous characteristics for bio-diesel incorporation and, up to 17%, density become also constraining. However, the low bio-diesel sulphur content could become interesting from now to 2010. On the basis of this bio-diesel demand analysis, we proceed to an external coupling of an agro-industrial model of bio-diesel supply with the French refining model. Thus, we study the impact of the 2010 French bio-diesel consumption objective on agricultural surface need, the competitiveness of the bio-diesel, the reduction of greenhouse gases emissions and the trade balance of the petroleum products. On this basis, we propose a critical analysis of French bio-diesel promoting measures under consideration by 2010. (author)

  18. High oleic sunflower bio diesel: quality control and different purification methods

    Energy Technology Data Exchange (ETDEWEB)

    Pighlinelli, A. L. M. T.; Ferrari, R. A.; Miguel, A. M. R. O.; Park, K. J.

    2011-07-01

    The objective of the present work is to evaluate the production of bio diesel using ethanol and sunflower oil. The extraction of the sunflower oil was evaluated first. An experimental design was used to estimate the influence of the independent variables grain temperature (25 degree centigrade to 110 degree centigrade) and expelled rotation (85 to 119rpm) on the crude oil. The best result obtained was 68.38%, achieved with a rotation from 100 to 115rpm, grain temperature ranging from 25 degree centigrade to 30 degree centigrade and moisture content of around 7%. The next study consisted of transesterification, evaluating the influence of the ethanol, oil molar ratio and the catalyst concentration (sodium methylate) on the ester-rich phase yield. The highest yield was 98.39% obtained with a molar ratio of 9:1 and 3% catalyst. An experiment was then carried out on a small reactor and the bio diesel produced was purified by three different methods: acidified water, silica and distillation. The quality aspects of the purified bio diesel samples were evaluated according to the Brazilian specifications for bio diesel, and distillation was shown to be the best method of purification. (Author) 28 refs.

  19. Performance of compression ignition engine with indigenous castor oil bio diesel in Pakistan

    International Nuclear Information System (INIS)

    Chakrabarti, M.H.

    2009-01-01

    Castor oil available indigenously in Pakistan was converted successfully to bio diesel and blended to 10% quantity (by volume) with high speed mineral diesel (HSD) fuel. This fuel was tested in a compression-ignition engine in order to assess its environmental emissions as well as engine performance parameters. The blended fuel was found to give lower environmental emissions in most accounts except for higher CO/sub 2/ and higher NOx. In addition, three engine performance parameters were assessed; which were engine brake power, engine torque and exhaust temperature. In the first two cases, blended bio diesel fuel gave lower figures than pure mineral diesel due to lower calorific value. However, its higher flash point resulted in higher engine exhaust temperatures than pure mineral diesel. Overall, in terms of engine performance, castor oil bio diesel (from non edible oil of castor bean -growing on marginal lands of Pakistan) fared better in comparison to canola oil bio diesel (from expensive edible oil) and can be recommended for further tests at higher blend ratios. (author)

  20. CO{sub 2} reduction cost for bio-diesel, Danish produced bio-diesel based on rape seed; CO{sub 2} reduktionsomkostninger ved biodiesel. Dansk produceret biodiesel pae raps

    Energy Technology Data Exchange (ETDEWEB)

    Carlsen, Kirsten; Kjellingbro, M; Mogensen, Martin Frank; Kohl, M

    2006-12-15

    Bio-diesel based on rape seed (RME, Rape Methyl Esther), often referred to as first generation bio-diesel, is a renewable fuel with CO{sub 2} reduction potential. Mixed with conventional diesel it can be used directly in existing diesel engines. The EU target for the use of bio-fuels in the transport sector was 2 % by 2005 and is 5.75 % by 2010. In Denmark, the use of bio-fuels in the transport sector is not viewed as a cost-effective CO{sub 2} reduction measure. This conclusion concerning the cost-effectiveness of bio-fuels was partly based on calculations of the CO2 reduction cost for Danish-produced RME made by the Danish Energy Authority in 2003. At that time the cost was estimated at 360 DKK/tonne CO{sub 2}. Since then some of the assumptions behind the calculations have changed. The overall objective of this report is to update the Danish Energy Authority's study from 2003, taking into account revised assumptions. The report also attempts to examine the uncertainties associated with the calculations by including extended sensitivity analyses. The report draws the following conclusions: 1) The CO{sub 2} reduction cost for Danish produced RME is estimated at 860 DKK/tonne CO{sub 2}, which is significantly higher than the result obtained by the Danish Energy Authority in 2003. 2) The difference from the Danish Energy Authority's original calculations is principally due to a higher rape seed price based on the market price on rape seed. 3) The uncertainty in both estimates is substantial, and there is about 15 % probability of the reduction costs being lower than the target of 180 DKK/tonne CO2 set by the government. (au)

  1. CO{sub 2} reduction cost for bio-diesel, Danish produced bio-diesel based on rape seed; CO{sub 2} reduktionsomkostninger ved biodiesel. Dansk produceret biodiesel pae raps

    Energy Technology Data Exchange (ETDEWEB)

    Carlsen, Kirsten; Kjellingbro, M.; Mogensen, Martin Frank; Kohl, M.

    2006-12-15

    Bio-diesel based on rape seed (RME, Rape Methyl Esther), often referred to as first generation bio-diesel, is a renewable fuel with CO{sub 2} reduction potential. Mixed with conventional diesel it can be used directly in existing diesel engines. The EU target for the use of bio-fuels in the transport sector was 2 % by 2005 and is 5.75 % by 2010. In Denmark, the use of bio-fuels in the transport sector is not viewed as a cost-effective CO{sub 2} reduction measure. This conclusion concerning the cost-effectiveness of bio-fuels was partly based on calculations of the CO2 reduction cost for Danish-produced RME made by the Danish Energy Authority in 2003. At that time the cost was estimated at 360 DKK/tonne CO{sub 2}. Since then some of the assumptions behind the calculations have changed. The overall objective of this report is to update the Danish Energy Authority's study from 2003, taking into account revised assumptions. The report also attempts to examine the uncertainties associated with the calculations by including extended sensitivity analyses. The report draws the following conclusions: 1) The CO{sub 2} reduction cost for Danish produced RME is estimated at 860 DKK/tonne CO{sub 2}, which is significantly higher than the result obtained by the Danish Energy Authority in 2003. 2) The difference from the Danish Energy Authority's original calculations is principally due to a higher rape seed price based on the market price on rape seed. 3) The uncertainty in both estimates is substantial, and there is about 15 % probability of the reduction costs being lower than the target of 180 DKK/tonne CO2 set by the government. (au)

  2. Emission Characteristics of CI Engine by using Palm BioDiesel

    OpenAIRE

    V.S.shai sundaram; S.S.shai monish

    2015-01-01

    Environmental concerns and energy crisis of the world has led to the search of alternate to the fossil fuel. FAME (Fatty Acid Methyl Ester) is environment friendly, alternative, and non-toxic, safe; biodegradable has a high flash point and is also termed as Bio-Diesel. The growing economic risk of relying primarily on fossil fuels with limited reserves and Increasing prices has increased the interest on alternative energy sources. Clean and renewable biofuels have been touted as t...

  3. Production of bio diesel from sludge palm oil by esterification using p-toluenesulfonic acid

    International Nuclear Information System (INIS)

    Adeeb Hayyan; Mohd Zahangir Alam; Mirghani, M.E.S.; Kabbashi, N.A.

    2009-01-01

    Full text: Sludge palm oil (SPO) is an attractive feedstock and a significant raw material for bio diesel production. The use of SPO as feedstock for bio diesel production requires additional pretreatment step to transesterification process, which is an esterification process. The most commonly preferred catalysts used in this process are sulfuric, sulphonic, hydrochloric and P-toluenesulfonic acid (PTSA). In this study bio diesel fuel was produced from SPO using PTSA as acid catalyst in different dosages in presence of alcohol to convert free fatty acid (FFA) to fatty acid methyl ester (FAME). Batch esterification process of SPO was carried out to study the influence of PTSA dosage (0.25-10 % wt/wt), molar ratio of methanol to SPO (6:1-20:1), temperature (40-80 degree Celsius), reaction time (30-120 min). The effects of those parameters on FFA content, yield of treated SPO and conversion of FFA to FAME were monitored. The study showed that the FFA content of SPO reduced from 22 % to less than 0.15 % using ratio of 0.5, 0.75, 1, 1.5, and 2 % wt/wt PTSA to SPO. After esterification process dosage of PTSA at 0.75 % wt/wt shows the highest conversion of FFA to FAME as well as yield of treated SPO. The optimum condition for batch esterification process was 10:1 molar ratio, temperature 60 degree Celsius and 60 minutes reaction time. The highest yield of bio diesel after transesterification process was 76.62 % with 0.06 % FFA and 93 % ester content. (author)

  4. Fundamentals of using bio-diesel for operating large fleets of mining equipment and building machines and the experience gained so far

    International Nuclear Information System (INIS)

    Drebenstedt, C.; Jauer, J.

    2008-01-01

    Against the topical background of the finite reserves of fossil mineral oil as well as internationally available vegetable fat and oil resources, of the current developments in the field of the biodiesel production technology and of the international conditions for the reduction of CO 2 emissions, this paper is to examine, whether the suitability of bio-diesel for fuelling mining equipment has come true. The examination will focus on the biogenic fuel profile, on the organizational necessity to actively retrofit the machinery during operations as well as on the precise verification of the expected technical conversion problems and of the saving potentials actually achieved. The examination will be conducted in the world's first open-cast mine that has converted its entire fleet of equipment to be fuelled with bio-diesel. The open-cast mine is operated by the Ronneburg branch of Wismut GmbH, a company based in Germany (referred to hereinafter as the Lichtenberg open-cast mine). (orig.)

  5. Sustainable Energy Production from Jatropha Bio-Diesel

    Science.gov (United States)

    Yadav, Amit Kumar; Krishna, Vijai

    2012-10-01

    The demand for petroleum has risen rapidly due to increasing industrialization and modernization of the world. This economic development has led to a huge demand for energy, where the major part of that energy is derived from fossil sources such as petroleum, coal and natural gas. Continued use of petroleum sourced fuels is now widely recognized as unsustainable because of depleting supplies. There is a growing interest in using Jatropha curcas L. oil as the feedstock for biodiesel production because it is non-edible and thus does not compromise the edible oils, which are mainly used for food consumption. Further, J. curcas L. seed has a high content of free fatty acids that is converted in to biodiesel by trans esterification with alcohol in the presence of a catalyst. The biodiesel produced has similar properties to that of petroleum-based diesel. Biodiesel fuel has better properties than petro diesel fuel; it is renewable, biodegradable, non-toxic, and essentially free of sulfur and aromatics. Biodiesel seems to be a realistic fuel for future. Biodiesel has the potential to economically, socially, and environmentally benefit communities as well as countries, and to contribute toward their sustainable development.

  6. French bio-diesel demand and promoting measures analysis by 2010; Analyse de la demande et des mesures de promotion francaises du biodiesel a l'horizon 2010

    Energy Technology Data Exchange (ETDEWEB)

    Bernard, F

    2008-02-15

    The researches presented aim at assessing bio-diesel promoting measures under consideration in France by 2010. This assessment is based on a deep study of French bio-diesel demand. The use of a linear model for optimizing the whole French refining industry costs allow us to take into account the physicochemical characteristics of bio-diesel useful for gas oil blending operation. This researches show that bio-diesel can be incorporated up to 27% blend in volume to diesel fuel without major technical problem. A decomposition of the value allotted to the bio-diesel by French refiners according to its physicochemical characteristics shows that energy content is the most disadvantageous characteristics for bio-diesel incorporation and, up to 17%, density become also constraining. However, the low bio-diesel sulphur content could become interesting from now to 2010. On the basis of this bio-diesel demand analysis, we proceed to an external coupling of an agro-industrial model of bio-diesel supply with the French refining model. Thus, we study the impact of the 2010 French bio-diesel consumption objective on agricultural surface need, the competitiveness of the bio-diesel, the reduction of greenhouse gases emissions and the trade balance of the petroleum products. On this basis, we propose a critical analysis of French bio-diesel promoting measures under consideration by 2010. (author)

  7. Experimental assessment of toxic phytochemicals in Jatropha curcas: oil, cake, bio-diesel and glycerol.

    Science.gov (United States)

    Pradhan, Subhalaxmi; Naik, S N; Khan, M Ashhar I; Sahoo, P K

    2012-02-01

    Jatropha curcas seed is a rich source of oil; however, it can not be utilised for nutritional purposes due to presence of toxic and anti-nutritive compounds. The main objective of the present study was to quantify the toxic phytochemicals present in Indian J. curcas (oil, cake, bio-diesel and glycerol). The amount of phorbol esters is greater in solvent extracted oil (2.8 g kg⁻¹) than in expeller oil (2.1 g kg⁻¹). Liquid chromatography-mass spectroscopy analysis of the purified compound from an active extract of oil confirmed the presence of phorbol esters. Similarly, the phorbol esters content is greater in solvent extracted cake (1.1 g kg⁻¹) than in cake after being expelled (0.8 g kg⁻¹). The phytate and trypsin inhibitory activity of the cake was found to be 98 g kg⁻¹ and 8347 TIU g⁻¹ of cake, respectively. Identification of curcin was achieved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and the concentration of curcin was 0.95 g L⁻¹ of crude concentrate obtained from cake. Higher amounts of phorbol esters are present in oil than cake but bio-diesel and glycerol are free of phorbol esters. The other anti-nutritional components such as trypsin inhibitors, phytates and curcin are present in cake, so the cake should be detoxified before being used for animal feed. Copyright © 2011 Society of Chemical Industry.

  8. Retrospect and prospects of edible oil and bio-diesel in Pakistan - a review

    International Nuclear Information System (INIS)

    Zaman, S.B.; Majeed, S.; Ahmad, S.

    2010-01-01

    Globally resources of petro-fuels are diminishing at a rapid rate. Efforts are underway to develop sources of bio-fuels. Out of the known sources of bio-fuels, Jatropha is one of the most promising option. The purpose of this study was to evaluate primarily the regional and global experiences to assess the potential of Jatropha farming in Pakistan and to conduct a comparative economic analysis of alternate feasible options e.g. production of oilseeds, which are also being imported in large quantities. Temporal analysis (1950-09) for edible oil consumption, production and imports is made. Projections for edible oil are worked out up to 2030. As there have been large variations in yield of Jatropha reported by various studies conducted in India and other countries, therefore most reliable data have been selected for analysis to assess the prospects in Pakistan. Comparative economic analysis is made in terms of oil contents, number of crops per year, yield and gross returns of oilseed crops and Jatropha. Analysis shows that increase in production of edible oil over the time is negligible against the large increase in requirement resulted in higher production gap being filled through imports. Projections made for edible oils illustrated that production gap is going to be wider, which is currently 1.86 million tonnes (mt) and projected to be 3.4 mt by 2030. Jatropha seed production analysis of water-yield functions revealed that yield varies from 1.1 t ha/sup -1/ in drought or dry spells to 12.75 t ha/sup -1/ with full irrigation in favorable environments. Benefit-cost analysis shows that break-even point can be achieved in fourth year of plantation of Jatropha. The projected consumption in Pakistan for petro-fuel for 2025 is 35.1 mt, which is almost double of the current consumption. Thus, the target projections for replacement of petro-fuel with bio-diesel will be 3.51 mt for which 3.5 mha of land is required, as Jatropha has to be grown in marginal areas with

  9. Multi-zone modeling of Diesel engine fuel spray development with vegetable oil, bio-diesel or Diesel fuels

    International Nuclear Information System (INIS)

    Rakopoulos, C.D.; Antonopoulos, K.A.; Rakopoulos, D.C.

    2006-01-01

    This work presents a model of fuel sprays development in the cylinders of Diesel engines that is two-dimensional, multi-zone, with the issuing jet (from the nozzle) divided into several discrete volumes, called 'zones', formed along the direction of the fuel injection as well as across it. The model follows each zone, with its own time history, as the spray penetrates into the swirling air environment of the combustion chamber before and after wall impingement. After the jet break up time, a group of droplets is generated in each zone, with the model following their motion during heating, evaporation and mixing with the in-cylinder air. The model is applied for the interesting case of using vegetable oils or their derived bio-diesels as fuels, which recently are considered as promising alternatives to petroleum distillates since they are derived from biological sources. Although there are numerous experimental studies that show curtailment of the emitted smoke with possible increase of the emitted NO x against the use of Diesel fuel, there is an apparent scarcity of theoretical models scrutinizing the formation mechanisms of combustion generated emissions when using these biologically derived fuels. Thus, in the present work, a theoretical detailed model of spray formation is developed that is limited to the related investigation of the physical processes by decoupling it from the chemical effects after combustion initiation. The analysis results show how the widely differing physical properties of these fuels, against the normal Diesel fuel, affect greatly the spray formation and consequently the combustion mechanism and the related emissions

  10. Feasibility of waste to Bio-diesel production via Nuclear-Biomass hybrid model. System dynamics analysis

    International Nuclear Information System (INIS)

    Nam, Hoseok; Kasada, Ryuta; Konishi, Satoshi

    2017-01-01

    Nuclear-Biomass hybrid system which takes waste biomass from municipal, agricultural area, and forest as feedstock produces Bio-diesel fuel from synthesis gas generated by endothermic pyrolytic gasification using high temperature nuclear heat. Over 900 degree Celsius of exterior thermal heat from nuclear reactors, Very High Temperature Reactor (VHTR) and some other heat sources, bring about waste biomass gasification to produce maximum amount of chemical energy from feedstock. Hydrogen from Biomass gasification or Bio-diesel as the product of Fischer-Tropsch reaction following it provide fuels for transport sector. Nuclear-Biomass hybrid system is a new alternatives to produce more energy generating synergy effects by efficiently utilizing the high temperature heat from nuclear reactor that might be considerably wasted by thermal cycle, and also energy loss from biomass combustion or biochemical processes. System Dynamics approach is taken to analyze low-carbon synthesis fuel, Bio-diesel, production with combination of carbon monoxide and hydrogen from biomass gasification. Feedstock cost considering collection, transportation, storage and facility for biomass gasification impacts the economic feasibility of this model. This paper provides the implication of practical nuclear-biomass hybrid system application with feedstock supply chain through evaluation of economic feasibility. (author)

  11. Bio-diesel fuels production: Feasibility studies. Se l'agricoltore semina il gasolio

    Energy Technology Data Exchange (ETDEWEB)

    Tabasso, L.

    This paper reviews the efforts being made by Italy's national government and private industry to develop diesel engine fuels derived from vegetable oils, in particular, sunflower seed oil. These fuels are being promoted in Italy from the environmental protection stand-point in that they don't contain any sulfur, the main cause of acid rain, and from the agricultural stand-point in that they provide Italian farmers, whose food crop production capacity is limited due to European Communities agreements, with the opportunity to use their set-aside land for the production of energy crops. This paper provides brief notes on the key performance characteristics of bio-diesel fuels, whose application doesn't require any modifications to diesel engines, apart from minor adjustments to the air/fuel mix regulating system, and assesses commercialization prospects. Brief mention is made of the problems being encountered by the Government in the establishing fair bio-fuel production tax rebates which are compatible with the marketing practices of the petroleum industry. One of the strategies being considered is to use the bio-fuels as additives to be mixed with conventional fuel oils so as to derive a fuel which meets the new European air pollution standards.

  12. Bio diesel Production via Transesterification of Palm Oil Using NaOH/ Al2O3 Catalysts

    International Nuclear Information System (INIS)

    Taufiq Yap Yun Hin; Nurul Fitriyah Abdullah; Mahiran Basri; Taufiq Yap Yun Hin; Nurul Fitriyah Abdullah

    2011-01-01

    Due to the increase in price of petroleum and environmental concerns, the search for alternative fuels has gained importance. In this work, bio diesel production by transesterification of palm oil with methanol has been studied in a heterogeneous system using sodium hydroxide loaded on alumina (NaOH/ Al 2 O 3 ). NaOH/ Al 2 O 3 catalyst was prepared by impregnation of alumina with different amount of an aqueous solution of sodium hydroxide followed by calcination in air for 3 h. The prepared catalysts were then characterized by using x-ray diffraction (XRD), Fourier transform infrared spectrometer (FT-IR), Brunner-Emmett-Teller surface area measurement (BET), scanning electron microscopy (SEM) and temperature-programmed desorption of CO 2 (CO 2 -TPD). Moreover, the dependence of the conversion of palm oil on the reactions variables such as the molar ratio of methanol/oil, the amount of catalysts used, reaction temperatures and reaction times were performed. The conversion of 99 % was achieved under the optimum reaction conditions. The bio diesel obtained was characterized by FT-IR and the pour point was measured. (author)

  13. Construction of combustion models for rapeseed methyl ester bio-diesel fuel for internal combustion engine applications.

    Science.gov (United States)

    Golovitchev, Valeri I; Yang, Junfeng

    2009-01-01

    Bio-diesel fuels are non-petroleum-based diesel fuels consisting of long chain alkyl esters produced by the transesterification of vegetable oils, that are intended for use (neat or blended with conventional fuels) in unmodified diesel engines. There have been few reports of studies proposing theoretical models for bio-diesel combustion simulations. In this study, we developed combustion models based on ones developed previously. We compiled the liquid fuel properties, and the existing detailed mechanism of methyl butanoate ester (MB, C(5)H(10)O(2)) oxidation was supplemented by sub-mechanisms for two proposed fuel constituent components, C(7)H(16) and C(7)H(8)O (and then, by mp2d, C(4)H(6)O(2) and propyne, C(3)H(4)) to represent the combustion model for rapeseed methyl ester described by the chemical formula, C(19)H(34)O(2) (or C(19)H(36)O(2)). The main fuel vapor thermal properties were taken as those of methyl palmitate C(19)H(36)O(2) in the NASA polynomial form of the Burcat database. The special global reaction was introduced to "crack" the main fuel into its constituent components. This general reaction included 309 species and 1472 reactions, including soot and NO(x) formation processes. The detailed combustion mechanism was validated using shock-tube ignition-delay data under diesel engine conditions. For constant volume and diesel engine (Volvo D12C) combustion modeling, this mechanism could be reduced to 88 species participating in 363 reactions.

  14. BioDiesel as Additive in High Pressure and Temperature Steam Recovery of Heavy Oil and Bitumen Utilisation d’un biogazole comme additif pour la récupération d’huile lourde et de bitume par injection de vapeur à hautes pression et température

    Directory of Open Access Journals (Sweden)

    Babadagli T.

    2012-05-01

    Full Text Available Use of additives to improve the efficiency of thermal heavy oil and bitumen recovery processes has been studied extensively over the decades. Two common types of additives used in thermal applications, mainly steam assisted recovery, are solvents and surfactants. Commercial use of solvents has setbacks due to their high costs and retrieval difficulties. Cost and stability of the surfactants under reservoir operating temperature and pressure are the major concerns. We propose the use of bioDiesel such as fatty acids methyl ester as a surfactant additive reducing heavy oil/bitumen-water interfacial tension in steam assisted recovery processes. Advantages of using bioDiesel as a surfactant additive are that bioDiesel is chemically stable under the operating pressure and temperature of the reservoir, it causes no harm on bitumen fuel quality and on release water chemistry and its use is economically feasible. We conducted a series of steam assisted bitumen recovery experiments to clarify the additional recovery potential and efficiency improvement capacity of bioDiesel. High pressure steam at 1.8 MPa pressure, 205°C was used in these tests at a 900 g/h feed rate. The porous media used was a normal grade oil sands ore obtained from a surface mine operation in Northern Alberta, Canada. Oil sands ore was packed in a basket and placed in a high pressure cell. Bitumen recovery experiments were performed by spraying canola oil fatty acid methyl ester on oil sands ore at a 2 g/kg-bitumen dosage. These tests show that bitumen recovery efficiency increases over 40%. In another series of tests, tall oil fatty acids methyl ester was injected into a high pressure steam line at a 8.3 g-bioDiesel/kg-steam dosage. Because of the solubility of bioDiesel in bitumen, the effect of bioDiesel on bitumen recovery could not be accurately concluded. Vapor pressure measurements performed on canola oil and tall oil derived bioDiesel samples suggest that saturation

  15. Analysis of first and second law of an engine operating with bio diesel from palm oil. Part 1: global energy balance

    International Nuclear Information System (INIS)

    Agudelo, John R; Agudelo, Andres F; Cuadrado, Ilba G.

    2006-01-01

    A first law of thermodynamics analysis in a diesel engine operating with palm oil bio diesel and its blends with diesel fuel is presented. Measurements were carried out in a test bench under stationary conditions varying engine load at constant speed and vice versa. The variation in energy distribution, efficiency, performance and emissions were obtained under several operating points. It was found that fuel type do not affect energy distribution and effective efficiency. On the other hand, engine operating conditions have an important effect on energy balance and performance. CO 2 emissions didn't exhibit a clear tendency with bio diesel concentration in the blend. Nevertheless, O 2 concentration in exhaust gases exhibits a direct relationship with this concentration, independent of engine operating condition.

  16. Study of turbocharged diesel engine operation, pollutant emissions and combustion noise radiation during starting with bio-diesel or n-butanol diesel fuel blends

    International Nuclear Information System (INIS)

    Rakopoulos, C.D.; Dimaratos, A.M.; Giakoumis, E.G.; Rakopoulos, D.C.

    2011-01-01

    Highlights: → Turbocharged diesel engine emissions during starting with bio-diesel or n-butanol diesel blends. → Peak pollutant emissions due to turbo-lag. → Significant bio-diesel effects on combustion behavior and stability. → Negative effects on NO emissions for both blends. → Positive effects on smoke emissions only for n-butanol blend. -- Abstract: The control of transient emissions from turbocharged diesel engines is an important objective for automotive manufacturers, as stringent criteria for exhaust emissions must be met. Starting, in particular, is a process of significant importance owing to its major contribution to the overall emissions during a transient test cycle. On the other hand, bio-fuels are getting impetus today as renewable substitutes for conventional fuels, especially in the transport sector. In the present work, experimental tests were conducted at the authors' laboratory on a bus/truck, turbocharged diesel engine in order to investigate the formation mechanisms of nitric oxide (NO), smoke, and combustion noise radiation during hot starting for various alternative fuel blends. To this aim, a fully instrumented test bed was set up, using ultra-fast response analyzers capable of capturing the instantaneous development of emissions as well as various other key engine and turbocharger parameters. The experimental test matrix included three different fuels, namely neat diesel fuel and two blends of diesel fuel with either bio-diesel (30% by vol.) or n-butanol (25% by vol.). With reference to the neat diesel fuel case during the starting event, the bio-diesel blend resulted in deterioration of both pollutant emissions as well as increased combustion instability, while the n-butanol (normal butanol) blend decreased significantly exhaust gas opacity but increased notably NO emission.

  17. Investigation of palm methyl-ester bio-diesel with additive on performance and emission characteristics of a diesel engine under 8-mode testing cycle

    Directory of Open Access Journals (Sweden)

    S. Senthilkumar

    2015-09-01

    Full Text Available Biodiesel is receiving increasing attention each passing day because of its same diesel-like fuel properties and compatibility with petroleum-based diesel fueled engines. Therefore, in this paper the prospects and opportunities of using various blends of methyl esters of palm oil as fuel in an engine with and without the effect of multi-functional fuel additive (MFA, Multi DM 32 are studied to arrive at an optimum blend of bio-diesel best suited for low emissions and minimal power drop. Experimental tests were conducted on a four stroke, three cylinder and naturally aspirated D.I. Diesel engine with diesel and various blend percentages of 20%, 40%, 45%, and 50% under the 8 mode testing cycle. The effect of fuel additive was tested out on the optimum blend ratio of the bio-diesel so as to achieve further reduced emissions. Comparison of results shows that, 73% reduction in hydrocarbon emission, 46% reduction in carbon monoxide emission, and around 1% reduction in carbon dioxide emission characteristics. So it is observed that the blend ratio of 40% bio-diesel with MFA fuel additive creates reduced emission and minimal power drop due to effective combustion even when the calorific value is comparatively lower due to its higher cetane number.

  18. Effect of temperature on the density of palm oil bio diesel and its blends with conventional diesel

    International Nuclear Information System (INIS)

    Benjumea H, Pedro N; Chaves N, German; Vargas R, Claudia M

    2006-01-01

    The density is a property of easy measurement which can be correlated with other key properties for evaluating fuel performance in diesel engines, such as calorific value and cetane number. Additionally, the density is one of the most important parameters in connection with fuel storage, transportation and commercialization. In this paper, experimental results showing the temperature dependence of the density for palm oil bio diesel and its 5% and 20% blends with conventional petroleum derived diesel fuel are presented. The experimental results were adequate fixed by linear regressions resulting in regression coefficients close to 1. For calculating the density of the BACPACPM blends a simple mixing law (weighted mass average) was proposed leading to absolute maximum deviations lesser than 0.5% of measured data. The density experimental results for the different tested fuels were compared with the estimated values from the volume correction method proposed by the Astm D1250 standard for hydrocarbon type fuels. For the neat BACP case (B100) the absolute maximum deviation was within 0.32% of measured data indicating that the mentioned correction method is also adequate for predicting the volumetric temperature behavior of substances having different chemical nature such as the methylesters of fatty acids.

  19. Experimental studies on natural aspirated diesel engine fuelled with corn seed oil methyl ester as a bio-diesel.

    Science.gov (United States)

    Rama Krishna Reddy, E.; Dhana Raju, V.

    2018-03-01

    This paper evaluates the possibilities of using corn seed oil methyl ester as a fuel for compression ignition engines. The biodiesels are contained high oxygen content, and high Cetane number, due to this properties efficiency of biodiesel is higher than diesel fuel. The experiments were conducted with different biodiesel blends of (B10, B15, B20 and B25) corn seed oil on single cylinder four stroke natural aspirated diesel engines. Performance parameters and exhaust emissions are investigated in this experimental with the blends of the corn seed oil methyl ester and diesel fuel. The test results showed that the bio-diesel blends gives improved results for brake thermal efficiency and specific fuel consumption when compared with the diesel fuel. The emissions of corn seed methyl esters follow the same trend of diesel but the smoke opacity was reduces for all blends. From the investigation, corn seed methyl ester is also having the properties similar to diesel fuel; it is biodegradable and renewable fuel, so it will be used as an alternative for diesel fuel.

  20. Studies on dual fuel operation of rubber seed oil and its bio-diesel with hydrogen as the inducted fuel

    Energy Technology Data Exchange (ETDEWEB)

    Edwin Geo, V.; Nagalingam, B. [Department of Mechanical Engineering, KCG College of Technology, Chennai, Tamil Nadu 600097 (India); Nagarajan, G. [Department of Mechanical Engineering, IC Engineering Division, Anna University, Chennai, Tamil Nadu 600025 (India)

    2008-11-15

    The main problems with the use of neat vegetable oils in diesel engines are higher smoke levels and lower thermal efficiency as compared to diesel. The problem can be tackled by inducting a gaseous fuel in the intake manifold along with air. In this investigation, hydrogen is used as the inducted fuel and rubber seed oil (RSO), rubber seed oil methyl ester (RSOME) and diesel are used as main fuels in a dual fuel engine. A single cylinder diesel engine with rated output of 4.4 kW at 1500 rpm was converted to operate in the dual fuel mode. Dual fuel operation of varying hydrogen quantity with RSO and RSOME results in higher brake thermal efficiency and significant reduction in smoke levels at high outputs. The maximum brake thermal efficiency is 28.12%, 29.26% and 31.62% with RSO, RSOME and diesel at hydrogen energy share of 8.39%, 8.73% and 10.1%, respectively. Smoke is reduced from 5.5 to 3.5 BSU with RSOME and for RSO it is from 6.1 to 3.8 BSU at the maximum efficiency point. The peak pressure and maximum rate of pressure rise increase with hydrogen induction. Heat release rate indicates an increase in the combustion rate with hydrogen induction. On the whole it is concluded that hydrogen can be inducted along with air in order to reduce smoke levels and improve thermal efficiency of RSO and its bio-diesel fuelled diesel engines. (author)

  1. Analysis of first and second law of an engine operating with Bio diesel from palm oil. Part 2: global exergy balance

    International Nuclear Information System (INIS)

    Agudelo, John R; Agudelo, Andres F; Cuadrado, Ilba G

    2006-01-01

    An exergy analysis of a diesel engine operating with palm oil bio diesel and its blends with diesel fuel is presented. Measurements were carried out in a test bench under stationary conditions varying engine load at constant speed and vice versa. The variation in exergy distribution and second law efficiency were obtained under several operating points. It was found that fuel type do not affect exergy distribution but it does affect the second law efficiency, which is slightly higher for diesel fuel. In contrast with energy balance results, exergy flows of exhaust and coolant streams are low, specially for the latter. This result is relevant for the implementation of cogeneration systems.

  2. Stability evaluation and chemical characterization of different vegetable oils viewing the search for candidates for certified reference materials for bio diesel; Avaliacao da estabilidade e caracterizacao quimica de diferentes oleos vegetais visando a busca de candidatos a materiais de referencia certificado (MRC) para biodiesel

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, Georgiana F. da; Fonseca, Mauricio G.; Goncalves, Lenise V.F.; Silva, Regina Celia F. da; Silva, Fernanda M.R. da; Rodrigues, Janaina M. [Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial (LABOR/INMETRO), Duque de Caxias, RJ (Brazil). Lab. de Analises Organicas; Leal, Rodrigo V.P. [Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial (LAMBOC/INMETRO), Duque de Caxias, RJ (Brazil). Lab. de Motores, Combustiveis e Lubrificantes], Email: rvleal@inmetro.gov.br; Cunha, Valnei S. [Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial (DIMCI/INMETRO), Duque de Caxias, RJ (Brazil). Diretoria de Metrologia Cientifica e Industrial

    2009-07-01

    Viewing the characterization of the various vegetable oils aiming to obtain a data bank that allows the production of certified reference materials for bio diesel of different blends, a study of chemical-physical characterization of different oils and derivative of bio diesel.

  3. Investigation of Bio-Diesel Fueled Engines under Low-Temperature Combustion Strategies

    Energy Technology Data Exchange (ETDEWEB)

    Chia-fon F. Lee; Alan C. Hansen

    2010-09-30

    In accordance with meeting DOE technical targets this research was aimed at developing and optimizing new fuel injection technologies and strategies for the combustion of clean burning renewable fuels in diesel engines. In addition a simultaneous minimum 20% improvement in fuel economy was targeted with the aid of this novel advanced combustion system. Biodiesel and other renewable fuels have unique properties that can be leveraged to reduce emissions and increase engine efficiency. This research is an investigation into the combustion characteristics of biodiesel and its impacts on the performance of a Low Temperature Combustion (LTC) engine, which is a novel engine configuration that incorporates technologies and strategies for simultaneously reducing NOx and particulate emissions while increasing engine efficiency. Generating fundamental knowledge about the properties of biodiesel and blends with petroleum-derived diesel and their impact on in-cylinder fuel atomization and combustion processes was an important initial step to being able to optimize fuel injection strategies as well as introduce new technologies. With the benefit of this knowledge experiments were performed on both optical and metal LTC engines in which combustion and emissions could be observed and measured under realistic conditions. With the aid these experiments and detailed combustion models strategies were identified and applied in order to improve fuel economy and simultaneously reduce emissions.

  4. Calophyllum inophyllum L. as a future feedstock for bio-diesel production

    Energy Technology Data Exchange (ETDEWEB)

    Atabania, A.E. [Department of Mechanical Engineering, University of Khartoum (Sudan)], email: a_atabani2@msn.com, email: ardinsu@yahoo.co.id; Silitonga, A.S.; Mahlia, T.M.I.; Masjukia, H.H.; Badruddin, I.A. [University of Malaya (Malaysia)

    2011-07-01

    Due to the energy crisis and the concerns about climate change, the possibility of using biodiesel as an alternative energy resource has been examined. It has been found that biodiesel could be a solution for the future but the first generation of biodiesel, prepared from edible vegetable oils, has raised important concerns about food and environmental problems. The aim of this study is to assess if Calophyllum inophyllum, a non-edible oil, could be used for biodiesel production. Density, kinematic viscosity, cetane number, flashpoint and iodine value were determined on Calophyllum inophyllum trees from Cilacap, Indonesia and compared in light of ASTM D6751 biodiesel standards. It was found that Calophyllum inophyllum would be a satisfactory feedstock to produce biodiesel in the future. This study demonstrated that Calophyllum inophyllum has the potential to be a biodiesel feedstock and further research should be carried out on engine performance, combustion and emission performance of biodiesel produced from Calophyllum inophyllum.

  5. Retro-analysis of liquid bio-ethanol and bio-diesel in New Zealand

    International Nuclear Information System (INIS)

    Krumdieck, S.; Page, S.

    2013-01-01

    This paper uses a new approach of retro-analysis. Typically policy is informed by forward-looking analysis of potential for alternative energy technologies. But historical knowledge of energy and processing requirements and greenhouse effects is more reliable for engineering evaluation of biofuel production systems. This study calculates energy inputs and greenhouse gas emissions for the most efficient biomass feedstocks in New Zealand if the policy had been implemented to maximize liquid biofuel production in the year 2004/2005. The study uses existing processing technologies and agricultural statistics. Bioethanol production is calculated from putrescible wastes and starch crops, and biodiesel production from rapeseed, tallow, wood and waste paper. Each production system is further evaluated using measures of land use, energy input, crop production related to the energy product, plus relative measures of efficiency and renewability. The research findings are that maximum biofuel production in 2004/2005 would have provided only a few per cent of demand, and would not have reduced dependence on foreign imported oil or exposure to fuel price rise. Finally, we conclude that demand management and efficiency are more effective means of meeting policy objectives. -- Graphical abstract: Input-output energy flows for liquid biofuels with retro-analysis reference to 2004. Display Omitted -- Highlights: •We conducted a Retro-analysis of biofuel production for New Zealand in 2004. •EROI analysis shows biodiesel from oil crops is the only viable biofuel. •Renewability analysis shows biofuels do not reduce exposure to peak oil issues. •GHG analysis shows 89% CO 2 emission reductions for the best biodiesel. •Total biofuel from food crops and wastes could provide less than 10% of demand

  6. Comparative performance and emissions study of a direct injection Diesel engine using blends of Diesel fuel with vegetable oils or bio-diesels of various origins

    International Nuclear Information System (INIS)

    Rakopoulos, C.D.; Antonopoulos, K.A.; Rakopoulos, D.C.; Hountalas, D.T.; Giakoumis, E.G.

    2006-01-01

    An extended experimental study is conducted to evaluate and compare the use of various Diesel fuel supplements at blend ratios of 10/90 and 20/80, in a standard, fully instrumented, four stroke, direct injection (DI), Ricardo/Cussons 'Hydra' Diesel engine located at the authors' laboratory. More specifically, a high variety of vegetable oils or bio-diesels of various origins are tested as supplements, i.e. cottonseed oil, soybean oil, sunflower oil and their corresponding methyl esters, as well as rapeseed oil methyl ester, palm oil methyl ester, corn oil and olive kernel oil. The series of tests are conducted using each of the above fuel blends, with the engine working at a speed of 2000 rpm and at a medium and high load. In each test, volumetric fuel consumption, exhaust smokiness and exhaust regulated gas emissions such as nitrogen oxides (NO x ), carbon monoxide (CO) and total unburned hydrocarbons (HC) are measured. From the first measurement, specific fuel consumption and brake thermal efficiency are computed. The differences in the measured performance and exhaust emission parameters from the baseline operation of the engine, i.e. when working with neat Diesel fuel, are determined and compared. This comparison is extended between the use of the vegetable oil blends and the bio-diesel blends. Theoretical aspects of Diesel engine combustion, combined with the widely differing physical and chemical properties of these Diesel fuel supplements against the normal Diesel fuel, are used to aid the correct interpretation of the observed engine behavior

  7. Factors and motivations of decision making process of the bio diesel productive chain in Rio Grande do Sul, Brazil; Fatores e motivacoes do processo de tomada de decisao da cadeia produtiva do biodiesel no Rio Grande do Sul

    Energy Technology Data Exchange (ETDEWEB)

    Rathmann, Regis; Santos, Omar Inacio Benedetti [Universidade Federal do Rio de Janeiro (COPPE/UFRJ), RJ (Brazil). Coordenacao dos Programas de Pos-Graduacao de Engenharia. Programa de Planejamento Energetico], e-mail: rathamnn@ppe.ufrj.br, e-mail: omarbenedetti@ppe.ufrj.br

    2008-07-01

    This article identifies, characterizes an analyses the factors, motivations and criteria which are been considered in the decision making process of the actors belonging to the bio diesel production chain at the Rio Grande do Sul, Brazil, and verifies the existence of alignment in the decision processes.

  8. Prediction of the thermal expansion coefficients of bio diesels from several sources through the application of linear regression; Predicao dos coeficientes de expansao termica de biodieseis de diversas origens atraves da aplicacao da regressa linear

    Energy Technology Data Exchange (ETDEWEB)

    Canciam, Cesar Augusto [Universidade Tecnologica Federal do Parana (UTFPR), Campus Ponta Grossa, PR (Brazil)], e-mail: canciam@utfpr.edu.br

    2012-07-01

    When evaluating the consumption of bio fuels, the knowledge of the density is of great importance for rectify the effect of temperature. The thermal expansion coefficient is a thermodynamic property that provides a measure of the density variation in response to temperature variation, keeping the pressure constant. This study aimed to predict the thermal expansion coefficients of ethyl bio diesels from castor beans, soybeans, sunflower seeds and Mabea fistulifera Mart. oils and of methyl bio diesels from soybeans, sunflower seeds, souari nut, cotton, coconut, castor beans and palm oils, from beef tallow, chicken fat and hydrogenated vegetable fat residual. For this purpose, there was a linear regression analysis of the density of each bio diesel a function of temperature. These data were obtained from other works. The thermal expansion coefficients for bio diesels are between 6.3729x{sup 10-4} and 1.0410x10{sup -3} degree C-1. In all the cases, the correlation coefficients were over 0.99. (author)

  9. Influence of High Temperature and Duration of Heating on the Sunflower Seed Oil Properties for Food Use and Bio-diesel Production.

    Science.gov (United States)

    Giuffrè, Angelo Maria; Capocasale, Marco; Zappia, Clotilde; Poiana, Marco

    2017-01-01

    Two important problems for the food industry are oil oxidation and oil waste after frying. Sunflower seed oil is one of the vegetable oils most commonly used in the food industry. Two variables were applied to the low oleic sunflower seed oil in this work i.e. heating temperature (180-210-240°C) and time of heating (15-30-60-120 minutes), to study from the edible point of view the variations of its physico-chemical properties. After 120 minutes heating at 240°C the following was found: refractive index (1.476), free acidity (0.35%), K232 (2.87), K270 (3.71), antiradical activity (45.90% inhibition), total phenols (523 mg kg -1 ), peroxide value (17.00 meq kg -1 ), p-anisidine value (256.8) and Totox (271.7), all of which showed a constant deterioration. In relation to the use as a feedstock for bio-diesel production, after 120 minutes heating at 240℃ the following was found: acid value 0.70 mg KOH g -1 oil, iodine value 117.83 g I 2 100 g -1 oil, oil stability index 0.67 h, kinematic viscosity (at 40°C) 77.85 mm 2 s -1 , higher heating value 39.86 MJ kg -1 , density 933.34 kg/m 3 and cetane number 67.04. The parameters studied in this work were influenced, in different ways, by the applied variables. Heating temperature between 180 and 210°C and 120 min heating duration were found to be the most appropriate conditions for sunflower seed oil both from the deep frying point of view and from a subsequent use as feedstock for bio-diesel production. In light of the vegetable oils' International standards for an edible use and for a bio-diesel production, findings of this work can be used to set heating temperature and heating duration to preserve as long possible the physico-chemical properties of a low oleic sunflower seed oil for both its edible use as a fat during cooking and for its re-use after frying.

  10. Physico-chemical, spectroscopical and thermal characterization of bio diesel obtained by enzymatic route as a tool to select the most efficient immobilized lipase

    International Nuclear Information System (INIS)

    Silva, G.A.M.; Ros, P.C.M. da; Souza, L.T.A.; Costa, A.P.O.; Castro, H.F. de

    2012-01-01

    Two microbial lipases from Burkholderia cepacia and Pseudomonas fluorescens were evaluated as catalysts for the enzymatic transesterification of beef tallow with ethanol and the most efficient lipase source was selected by taking into account the properties of the product to be used as fuel. Both lipases were immobilized on an epoxy silica-polyvinyl alcohol composite by covalent immobilization and used to perform the reactions under the following operational conditions: beef tallow-to-ethanol molar ratio of 1:9, 45 degree C and 400 units of enzymatic activity per gram of fat. Products, characterized using Fourier Transform Infrared spectroscopy (FTIR), viscosimetry, thermogravimetry and 1 H NMR spectroscopy, suggested that the bio diesel sample obtained in the reaction catalyzed by Burkholderia cepacia lipase has the best set of properties for fuel usage. (author)

  11. Physico-chemical, spectroscopical and thermal characterization of bio diesel obtained by enzymatic route as a tool to select the most efficient immobilized lipase

    Energy Technology Data Exchange (ETDEWEB)

    Silva, G.A.M.; Ros, P.C.M. da; Souza, L.T.A.; Costa, A.P.O.; Castro, H.F. de, E-mail: heizir@dequi.eel.usp.br [Engineering School of Lorena. University of Sao Paulo (EEL/USP), Lorena, SP (Brazil)

    2012-01-15

    Two microbial lipases from Burkholderia cepacia and Pseudomonas fluorescens were evaluated as catalysts for the enzymatic transesterification of beef tallow with ethanol and the most efficient lipase source was selected by taking into account the properties of the product to be used as fuel. Both lipases were immobilized on an epoxy silica-polyvinyl alcohol composite by covalent immobilization and used to perform the reactions under the following operational conditions: beef tallow-to-ethanol molar ratio of 1:9, 45 degree C and 400 units of enzymatic activity per gram of fat. Products, characterized using Fourier Transform Infrared spectroscopy (FTIR), viscosimetry, thermogravimetry and {sup 1}H NMR spectroscopy, suggested that the bio diesel sample obtained in the reaction catalyzed by Burkholderia cepacia lipase has the best set of properties for fuel usage. (author)

  12. Optimization Of Process Parameters For The Production Of Bio diesel From Waste Cooking Oil In The Presence Of Bifunctional γ-Al2O3-CeO2 Supported Catalysts

    International Nuclear Information System (INIS)

    Anita Ramli; Muhammad Farooq

    2015-01-01

    Huge quantities of waste cooking oils are produced all over the world every day, especially in the developed countries with 0.5 million ton per year waste cooking oil are being generated in Malaysia alone. Such large amount of waste cooking oil production can create disposal problems and contamination to water and land resources if not disposed properly. The use of waste cooking oil as feedstock for bio diesel production will not only avoid the competition of the same oil resources for food and fuel but will also overcome the waste cooking oil disposal problems. However, waste cooking oil has high acid value, thus would require the oil to undergo esterification with an acid catalyst prior to transesterification with a base catalyst. Therefore, in this study, bifunctional catalyst supports were developed for one-step esterification-transesterification of waste cooking oil by varying the CeO 2 loading on γ-Al 2 O 3 . The bifunctional supports were then impregnated with 5 wt % Mo and characterized using N 2 adsorption-desorption isotherm to determine the surface area of the catalysts while temperature programmed desorption with NH 3 and CO 2 as adsorbents were used to determine the acidity and basicity of the catalysts. Results show that the γ-Al 2 O 3 -CeO 2 supported Mo catalysts are active for the one-step esterification-transesterification of waste cooking oil to produce bio diesel with the Mo/ γ-Al 2 O 3 -20 wt% CeO 2 as the most active catalyst. Optimization of process parameters for the production of bio diesel from waste cooking oil in the presence of this catalyst show that 81.1 % bio diesel yield was produced at 110 degree Celsius with catalyst loading of 7 wt %, agitation speed of 600 rpm, methanol to oil ratio of 30:1 and reaction period of 270 minutes. (author)

  13. African Initiated Churches’ potential as development actors

    Directory of Open Access Journals (Sweden)

    Philipp Öhlmann

    2016-11-01

    Full Text Available African Initiated Churches (AICs are not yet recognised as relevant actors of community development interventions. While it has been acknowledged that many of them provide coping mechanisms in adverse environments, support in social transformation and social capital, little information is available on their role as development actors. In this article, we evaluate the potential of AICs as partners of international development agencies for community development. We draw on interviews and focus group discussions with leaders of various AICs conducted in South Africa in February and March 2016. In particular, we examine the churches’ understanding of development, their view on the separation of spiritual and development activities and their priorities. Moreover, we outline the development activities which they are currently engaged in and analyse the structures they have in place to do so. Our findings indicate that AICs are increasingly active in community development and offer various entry points for possible cooperation.

  14. Effects of Alumina Nano Metal Oxide Blended Palm Stearin Methyl Ester Bio-Diesel on Direct Injection Diesel Engine Performance and Emissions

    Science.gov (United States)

    Krishna, K.; Kumar, B. Sudheer Prem; Reddy, K. Vijaya Kumar; Charan Kumar, S.; Kumar, K. Ravi

    2017-08-01

    The Present Investigation was carried out to study the effect of Alumina Metal Oxide (Al2O3) Nano Particles as additive for Palm Stearin Methyl Ester Biodiesel (B 100) and their blends as an alternate fuel in four stroke single cylinder water cooled, direct injection diesel engine. Alumina Nano Particles has high calorific value and relatively high thermal conductivity (30-1 W m K-1) compare to diesel, which helps to promote more combustion in engines due to their higher thermal efficiency. In the experimentation Al2O3 were doped in various proportions with the Palm Stearin Methyl Ester Biodiesel (B-100) using an ultrasonicator and a homogenizer with cetyl trimethyl ammonium bromide (CTAB) as the cationic surfactant. The test were performed on a Kirsloskar DI diesel engine at constant speed of 1500 rpm using different Nano Biodiesel Fuel blends (psme+50 ppm, psme+150 ppm, and psme+200 ppm) and results were compared with those of neat conventional diesel and Palm Stearin Methyl Ester Bio diesel. It was observed that for Nano Biodiesel Fuel blend (psme+50ppm) there is an significant reduction in carbon monoxide (CO) emissions and Nox emissions compared to diesel and the brake thermal efficiency for (psme+50ppm) was almost same as diesel.

  15. Potential of production of biodiesel starting from the chicken oil in the cooperatives of the West of Parana, Brazil; Potencial de producao de biodiesel a partir do oleo de frango nas cooperativas do oeste do Parana

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Samuel Nelson Melegari de [Universidade Estadual do Oeste do Parana (CCET/UNIOESTE), Cascavel, PR (Brazil). Centro de Ciencias Exatas e Tecnologicas], Email: ssouza@unioeste.br; Neitzke, Guilherme [Universidade Estadual do Oeste do Parana (PIBIC/CCET/UNIOESTE), Cascavel, PR (Brazil). Centro de Ciencias Exatas e Tecnologicas. Programa Institucional de Bolsas de Iniciacao Cientifica; Gomes, Luis Fernando Souza [Colegio Estadual Presidente Castelo Branco, Toledo, PR (Brazil)], Email: luisfsg@ibest.com.br; Bariccatti, Reinaldo Aparecido [Universidade Estadual do Oeste do Parana (CECE/UNIOESTE), Toledo, PR (Brazil). Centro de Engenharia e Ciencias Exatas], Email: bariccatti@unioeste.br

    2006-07-01

    Brazil occupies a prominence place in the development and use of sources renovate of energy, due to its great territorial extension, climate and several alternatives. One of these it is the bio diesel,o production which can substitute the oil diesel, decreasing the impacts to the environment. In the productive chain of chicken meat a residue, chicken oil, is generated with potential for biodiesel production. In this work they were certain characteristics physical chemistries, that can influence in the reactions of transesterification of the chicken oil. It was lifted up the potential of production of chicken oil in the cooperatives of the area west of the state of Parana and yield in biodiesel. The bio diesel production by cooperatives could be of 19.525.209,0 kg/year of bio diesel and the yield of 95%. (author)

  16. Evaluation of fuel properties for microalgae Spirulina platensis bio-diesel and its blends with Egyptian petro-diesel

    Directory of Open Access Journals (Sweden)

    Soha S.M. Mostafa

    2017-05-01

    In this study, the feasibility of biodiesel production from microalga Spirulina platensis has been investigated. The physico–chemical characteristics of the produced biodiesel were studied according to the standards methods of analysis (ASTM and evaluated according to their fuel properties as compared to Egyptian petro-diesel. Blends of microalgae biodiesel and petro-diesel (B2, B5, B10 and B20 were prepared on a volume basis and their physico–chemical characteristics have been also studied. The obtained results showed that; with the increase of biodiesel concentration in the blends; the viscosity, density, total acid number, initial boiling point, calorific value, flash point, cetane number and diesel index increase. While the pour point, cloud point, carbon residue and sulfur, ash and water contents decrease. The observed properties of the blends were within the recommended petro-diesel standard specifications and they are in favor of better engine performance.

  17. Replacement of ultrasonic energy as the heat source for a greener bio diesel production: A response surface methodology

    International Nuclear Information System (INIS)

    Babak Salamatinia; Hamed Mootabadi; Subhash Bhatia; Ahmad Zuhairi Abdullah

    2010-01-01

    The use of ultrasonic energy for mixing and the subsequent conversion to heat energy in the transesterification reaction of vegetable oil is reported. Effects of 5 important variables i.e. pulse on (s), pulse off (s), reaction time (min), power (%) and oil volume (ml) at constant alcohol to palm oil molar ratio (9:1) and initial reaction temperature of 35 degree Celsius were studied. A central composite design (CCD) using response surface technology (RSM) was employed. The results indicated that the reaction time did not play much role as the system reached steady state within the first few minutes. Longer the pulse on and the lower the pulse off at 70 % of the maximum power of could bring the reaction to desired temperature for volume of up to 60 ml. A model was proposed based on heat capacity of reactants for conversion of ultrasonic into heat and the final temperature of the system could be predicted. This model was tested with 5 types of vegetable oil including used palm oil, canola oil, sunflower oil and corn oil to study the effect of specific heat capacity of the oil. Three different types of catalysts with varying heat capacities were also tested for verification of the model. The model developed showed good predictions with less than 5 % error in different conditions. (author)

  18. Development and application of multi-zone model for combustion and pollutants formation in direct injection diesel engine running with vegetable oil or its bio-diesel

    International Nuclear Information System (INIS)

    Rakopoulos, C.D.; Antonopoulos, K.A.; Rakopoulos, D.C.

    2007-01-01

    A multi-zone model for calculation of the closed cycle of a direct injection (DI) Diesel engine is presented and applied for the interesting case of its operation with vegetable oil (cottonseed) or its derived bio-diesel (methyl ester) as fuels, which recently are considered as promising alternatives (bio-fuels) to petroleum distillates. Although there are many experimental studies, there is an apparent scarcity of theoretical models scrutinizing the formation mechanisms of combustion generated emissions when using these fuels. The model is two dimensional, multi-zone with the issuing jets (from the nozzle) divided into several discrete volumes, called 'zones', formed along the direction of the fuel injection and across it. The model follows each zone, with its own time history, as the spray penetrates into the swirling air environment (forming the non-burning zone) of the combustion chamber, before and after wall impingement. Droplet evaporation and jet mixing models are used to determine the amount of fuel and entrained air in each zone available for combustion. The mass, energy and state equations are applied in each zone to yield local temperatures and cylinder pressure histories. The concentrations of the various constituents are calculated by adopting a chemical equilibrium scheme for the C-H-O-N system of 11 species considered, together with the chemical rate equations for the calculation of nitric oxide (NO). A model for evaluation of soot formation and oxidation rates is included. The results from the relevant computer program for the in cylinder pressure, exhaust nitric oxide concentration (NO) and soot density are compared favorably with the corresponding measurements from an experimental investigation conducted on a fully automated test bed, standard 'Hydra', DI Diesel engine installed at the authors' laboratory. Iso-contour plots of equivalence ratio, temperature, NO and soot inside the combustion chamber at various instants of time when using these

  19. Algae for Bio diesel production

    International Nuclear Information System (INIS)

    Bravi, M.; De Filippis, P.; Balestrieri, M.

    2008-01-01

    A sustainable bio fuels production cannot ignore the competition between the food and agroenergy chains for the cultivable land, and many advocate oleaginous microbial biomass as a possible solution to this problem. Their advantages include fast growth, significant oil content, productivity significantly larger than that featured by higher plants but, most importantly, the possibility of exploiting marginal lands. Before they can be deployed on a large scale, some remaining critical points must be solved

  20. Physiochemical, energy characteristics and performance of coconut fiber in the sorption of diesel and bio diesel oils; Caracteristicas fisico-quimicas, energetica e desempenho da fibra de coco na sorcao de oleos diesel e biodiesel

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Adriana Ferla de [Pos-Graduacao em Agronomia - Energia na Agricultura, Faculdade de Ciencias Agronomicas, Universidade Estadual Paulista - FCA/UNESP, Botucatu, SP (Brazil); Curso Superior de Tecnologia em Biocombustiveis, Universidade Federal do Parana - UFPR, Palotina, PR (Brazil)], e-mail: adrianaferla@ufpr.br; Leao, Alcides Lopes [Dept. de Recursos Naturais, Faculdade de Ciencias Agronomicas, Universidade Estadual Paulista - FCA/UNESP, Botucatu, SP (Brazil)], e-mail: alcidesleao@fca.unesp.br; Caraschi, Jose Claudio [Universidade Estadual Paulista - UNESP, Itapeva, SP (Brazil)], e-mail: carachi@itapeva.unesp.br; Oliveira, Luciano Caetano de [Curso de Agronomia, Universidade Federal do Parana - UFPR, Palotina, PR (Brazil)], e-mail: lucianocaetano@ufpr.br; Goncalves, Jose Evaristo [Pos-Graduacao em Agronomia - Energia na Agricultura, Faculdade de Ciencias Agronomicas, Universidade Estadual Paulista - FCA/UNESP, Botucatu, SP (Brazil)], e-mail: evaristto@yahoo.com.br

    2011-07-01

    Accidents involving oil spills and its derivatives on the soil and in hydric bodies are common and worrying once they endanger the quality of the ecosystem. An economical and efficient way of combating oil spills is the use of the sorption method using sorbent materials. There is a range of sorbent materials, however, the natural ones like biomass and vegetable fibers demonstrate interest due to the low cost and good sorbent capacity. There are works concerning the sorption of crude oil, however for diesel and bio diesel, which had their production increased, there is a little or even nothing exists in the literature. The aim of this work was to investigate the sorption capacity of coconut fiber (Cocos nucifera) confronting to the fuels, diesel and biodiesel and to compare them with the peat commercially used. The bio sorbents were also submitted to the physiochemical and energy characterization. Most of the tests were performed on the granulometric size range of {<=}180 {mu}m 180-425 {mu}m; 425-850 {mu}m e 850-3350 {mu}m. The coir fiber presented capacity of diesel and bio diesel sorption similar to the commercial sorbent made of peat. The determination of the calorific power of the bio sorbents shows that they can be used for energy generation before and after they are used as sorbents. This way, those materials can be used after studies of economical viability in this sector and still to increase the economy of the areas where they are abundant. (author)

  1. Universal potential-barrier penetration by initially confined wave packets

    International Nuclear Information System (INIS)

    Granot, Er'el; Marchewka, Avi

    2007-01-01

    The dynamics of an initially sharp-boundary wave packet in the presence of an arbitrary potential barrier is investigated. It is shown that the penetration through the barrier is universal in the sense that it depends only on the values of the wave function and its derivatives at the boundary. The dependence on the derivatives vanishes at long distances from the barrier, where the dynamics is governed solely by the initial value of the wave function at the boundary

  2. Universal potential-barrier penetration by initially confined wave packets

    Science.gov (United States)

    Granot, Er'El; Marchewka, Avi

    2007-07-01

    The dynamics of an initially sharp-boundary wave packet in the presence of an arbitrary potential barrier is investigated. It is shown that the penetration through the barrier is universal in the sense that it depends only on the values of the wave function and its derivatives at the boundary. The dependence on the derivatives vanishes at long distances from the barrier, where the dynamics is governed solely by the initial value of the wave function at the boundary.

  3. Inhibition of autophagy initiation potentiates chemosensitivity in mesothelioma.

    Science.gov (United States)

    Follo, Carlo; Cheng, Yao; Richards, William G; Bueno, Raphael; Broaddus, Virginia Courtney

    2018-03-01

    The benefits of inhibiting autophagy in cancer are still controversial, with differences in outcome based on the type of tumor, the context and the particular stage of inhibition. Here, we investigated the impact of inhibiting autophagy at different stages on chemosensitivity using 3-dimensional (3D) models of mesothelioma, including ex vivo human tumor fragment spheroids. As shown by LC3B accumulation, we successfully inhibited autophagy using either an early stage ULK1/2 inhibitor (MRT 68921) or a late stage inhibitor (hydroxychloroquine). We found that inhibition of autophagy at the early stage, but not at late stage, potentiated chemosensitivity. This effect was seen only in those spheroids with high autophagy and active initiation at steady state. Inhibition of autophagy alone, at either early or late stage, did not cause cell death, showing that the inhibitors were non-toxic and that mesothelioma did not depend on autophagy at baseline, at least over 24 h. Using ATG13 puncta analysis, we found that autophagy initiation identified tumors that are more chemosensitive at baseline and after autophagy inhibition. Our results highlight a potential role of autophagy initiation in supporting mesothelioma cells during chemotherapy. Our work also highlights the importance of testing the inhibition of different stages in order to uncover the role of autophagy and the potential of its modulation in the treatment of cancer. © 2017 Wiley Periodicals, Inc.

  4. Energy for sustainable road transportation in China: Challenges, initiatives and policy implications

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Xiaojun; Chang, Shiyan; Li, Jingjie; Qin, Yining [Institute of Energy and Environmental Economics, Energy Science Building, Tsinghua University, Beijing 100084 (China)

    2010-11-15

    This paper presents an overview of the initiatives launched in energy supply and consumption and the challenges encountered in sustainable road transportation development in China. It analyzes the main energy challenges related to road transportation development arising in the context of economic development, rapid urbanization, and improvement in living standards. It also discusses technological- and policy initiatives needed to deal with these challenges, drawing comparisons with foreign experience: promoting the development and dissemination of alternative fuels and clean vehicles such as: LPG, CNG, EV, HEV, FCV, ethanol, methanol, DME, bio-diesel, and CTL, strengthening regulations relating to vehicle fuel economy and emission, improving traffic efficiency and facilitating public transport development, and strengthening management of the soaring motor vehicle population. If the current pattern continues, by the year 2030, the vehicle population in China will be 400 million and fuel demand will be 350 million tons. The potential energy saving capacity being 60%, the actual oil demand by 2030 from on-road vehicles might technically be kept at the current level by improving fuel economy, propagating use of HEV and diesel vehicles, improving supply of alternative fuels, and developing public transport. Several uncertainties are identified that could greatly influence the effect of the technical proposals: traffic efficiency, central government's resolve, and consumers' choice. (author)

  5. Potential GTCC LLW sealed radiation source recycle initiatives

    International Nuclear Information System (INIS)

    Fischer, D.

    1992-04-01

    This report suggests 11 actions that have the potential to facilitate the recycling (reuse or radionuclide) of surplus commercial sealed radiation sources that would otherwise be disposed of as greater-than-Class C low-level radioactive waste. The suggestions serve as a basis for further investigation and discussion between the Department of Energy, Nuclear Regulatory Commission, Agreement States, and the commercial sector. Information is also given that describes sealed sources, how they are used, and problems associated with recycling, including legal concerns. To illustrate the nationwide recycling potential, Appendix A gives the estimated quantity and application information for sealed sources that would qualify for disposal in commercial facilities if not recycle. The report recommends that the Department of Energy initiate the organization of a forum to explore the suggested actions and other recycling possibilities

  6. Identifying Initial Condition in Degenerate Parabolic Equation with Singular Potential

    Directory of Open Access Journals (Sweden)

    K. Atifi

    2017-01-01

    Full Text Available A hybrid algorithm and regularization method are proposed, for the first time, to solve the one-dimensional degenerate inverse heat conduction problem to estimate the initial temperature distribution from point measurements. The evolution of the heat is given by a degenerate parabolic equation with singular potential. This problem can be formulated in a least-squares framework, an iterative procedure which minimizes the difference between the given measurements and the value at sensor locations of a reconstructed field. The mathematical model leads to a nonconvex minimization problem. To solve it, we prove the existence of at least one solution of problem and we propose two approaches: the first is based on a Tikhonov regularization, while the second approach is based on a hybrid genetic algorithm (married genetic with descent method type gradient. Some numerical experiments are given.

  7. Perturbation analysis of spontaneous action potential initiation by stochastic ion channels

    KAUST Repository

    Keener, James P.; Newby, Jay M.

    2011-01-01

    A stochastic interpretation of spontaneous action potential initiation is developed for the Morris-Lecar equations. Initiation of a spontaneous action potential can be interpreted as the escape from one of the wells of a double well potential

  8. Documentation for calculating CO{sub 2} reduction costs of using bio diesel; Dokumentation for beregning af CO{sub 2}-reduktionsomkostningen ved anvendelse af biodiesel

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-01-01

    In connection to the European Commission's proposal for a directive on the promotion of biofuels for transport and the new climate strategy for Denmark, the Danish Energy Authority has evaluated the potential for and economics of production of biodiesel in Denmark. This note is documentation for the Danish Energy Authority's socio-economic analysis regarding rape-based biodiesel. The analysis consists of two parts: 1. Costs of producing biodiesel, 2. Costs of cultivating rape. The main conclusion is that the socio-economic CO{sub 2} reduction costs of producing biodiesel in Denmark are subject to some uncertainty. The uncertainty is primarily linked to difficulty in determining central parameters, e.g. stating the socio-economic costs of producing rape-seed, including stating prices of production factors and by-products. (ba)

  9. Biofuel initiatives in Japan: Strategies, policies, and future potential

    International Nuclear Information System (INIS)

    Matsumoto, Naoko; Sano, Daisuke; Elder, Mark

    2009-01-01

    Japan has developed a variety of national strategies and plans related to biofuels which address four main policy objectives, including reduction of greenhouse gas (GHG) emissions, energy security, rural development, and realisation of a recycle-based society. This paper reviews these national strategies and plans as well as associated implementing policies, and discusses the extent to which these objectives may be achieved. This paper found that the long-term potential of biofuels to contribute to GHG reduction goals will depend not only on the rates of technological development of the second generation biofuels but also on the development of other advanced vehicles. In the medium term, the potential contribution of biofuels to rural development and realising a recycle-based society could become significant depending on the progress of technology for both second generation biofuel production and the collection and transportation of their feedstocks. The potential contribution of biofuels to Japan's energy security is constrained by the availability of imports and the potential of domestic production. (author)

  10. 7 CFR 1945.19 - Reporting potential natural disasters and initial actions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Reporting potential natural disasters and initial... Assistance-General § 1945.19 Reporting potential natural disasters and initial actions. (a) Purpose. The purpose of reporting potential natural disasters is to provide a systematic procedure for rapid reporting...

  11. Bio-fuel production potential in Romania

    International Nuclear Information System (INIS)

    Laurentiu, F.; Silvian, F.; Dumitru, F.

    2006-01-01

    The paper is based on the ESTO Study: Techno- Economic Feasibility of Large-Scale Production of Bio-Fuels in EU-Candidate Countries. Bio-fuel production has not been taken into account significantly until now in Romania, being limited to small- scale productions of ethanol, used mostly for various industrial purposes. However the climatic conditions and the quality of the soil are very suitable in the country for development of the main crops (wheat, sugar-beet, sunflower and rape-seed) used in bio-ethanol and bio-diesel production. The paper intended to consider a pertinent discussion of the present situation in Romania's agriculture stressing on the following essential items in the estimation of bio-fuels production potential: availability of feed-stock for bio-fuel production; actual productions of bio-fuels; fuel consumption; cost assessment; SWOT approach; expected trends. Our analysis was based on specific agricultural data for the period 1996-2000. An important ethanol potential (due to wheat, sugar-beet and maize cultures), as well as bio-diesel one (due to sun-flower and rape-seed) were predicted for the period 2005-2010 which could be exploited with the support of an important financial and technological effort, mainly from EU countries

  12. Action potentials in retinal ganglion cells are initiated at the site of maximal curvature of the extracellular potential.

    Science.gov (United States)

    Eickenscheidt, Max; Zeck, Günther

    2014-06-01

    The initiation of an action potential by extracellular stimulation occurs after local depolarization of the neuronal membrane above threshold. Although the technique shows remarkable clinical success, the site of action and the relevant stimulation parameters are not completely understood. Here we identify the site of action potential initiation in rabbit retinal ganglion cells (RGCs) interfaced to an array of extracellular capacitive stimulation electrodes. We determine which feature of the extracellular potential governs action potential initiation by simultaneous stimulation and recording RGCs interfaced in epiretinal configuration. Stimulation electrodes were combined to areas of different size and were presented at different positions with respect to the RGC. Based on stimulation by electrodes beneath the RGC soma and simultaneous sub-millisecond latency measurement we infer axonal initiation at the site of maximal curvature of the extracellular potential. Stimulation by electrodes at different positions along the axon reveals a nearly constant threshold current density except for a narrow region close to the cell soma. These findings are explained by the concept of the activating function modified to consider a region of lower excitability close to the cell soma. We present a framework how to estimate the site of action potential initiation and the stimulus required to cross threshold in neurons tightly interfaced to capacitive stimulation electrodes. Our results underscore the necessity of rigorous electrical characterization of the stimulation electrodes and of the interfaced neural tissue.

  13. Multiple modes of action potential initiation and propagation in mitral cell primary dendrite

    DEFF Research Database (Denmark)

    Chen, Wei R; Shen, Gongyu Y; Shepherd, Gordon M

    2002-01-01

    recordings with computational modeling to analyze action-potential initiation and propagation in the primary dendrite. In response to depolarizing current injection or distal olfactory nerve input, fast Na(+) action potentials were recorded along the entire length of the primary dendritic trunk. With weak......-to-moderate olfactory nerve input, an action potential was initiated near the soma and then back-propagated into the primary dendrite. As olfactory nerve input increased, the initiation site suddenly shifted to the distal primary dendrite. Multi-compartmental modeling indicated that this abrupt shift of the spike......-initiation site reflected an independent thresholding mechanism in the distal dendrite. When strong olfactory nerve excitation was paired with strong inhibition to the mitral cell basal secondary dendrites, a small fast prepotential was recorded at the soma, which indicated that an action potential was initiated...

  14. Action potential generation requires a high sodium channel density in the axon initial segment

    NARCIS (Netherlands)

    Kole, Maarten H. P.; Ilschner, Susanne U.; Kampa, Björn M.; Williams, Stephen R.; Ruben, Peter C.; Stuart, Greg J.

    2008-01-01

    The axon initial segment ( AIS) is a specialized region in neurons where action potentials are initiated. It is commonly assumed that this process requires a high density of voltage-gated sodium ( Na(+)) channels. Paradoxically, the results of patch-clamp studies suggest that the Na(+) channel

  15. Perturbation analysis of spontaneous action potential initiation by stochastic ion channels

    KAUST Repository

    Keener, James P.

    2011-07-01

    A stochastic interpretation of spontaneous action potential initiation is developed for the Morris-Lecar equations. Initiation of a spontaneous action potential can be interpreted as the escape from one of the wells of a double well potential, and we develop an asymptotic approximation of the mean exit time using a recently developed quasistationary perturbation method. Using the fact that the activating ionic channel\\'s random openings and closings are fast relative to other processes, we derive an accurate estimate for the mean time to fire an action potential (MFT), which is valid for a below-threshold applied current. Previous studies have found that for above-threshold applied current, where there is only a single stable fixed point, a diffusion approximation can be used. We also explore why different diffusion approximation techniques fail to estimate the MFT. © 2011 American Physical Society.

  16. Dynamics of action potential initiation in the GABAergic thalamic reticular nucleus in vivo.

    Science.gov (United States)

    Muñoz, Fabián; Fuentealba, Pablo

    2012-01-01

    Understanding the neural mechanisms of action potential generation is critical to establish the way neural circuits generate and coordinate activity. Accordingly, we investigated the dynamics of action potential initiation in the GABAergic thalamic reticular nucleus (TRN) using in vivo intracellular recordings in cats in order to preserve anatomically-intact axo-dendritic distributions and naturally-occurring spatiotemporal patterns of synaptic activity in this structure that regulates the thalamic relay to neocortex. We found a wide operational range of voltage thresholds for action potentials, mostly due to intrinsic voltage-gated conductances and not synaptic activity driven by network oscillations. Varying levels of synchronous synaptic inputs produced fast rates of membrane potential depolarization preceding the action potential onset that were associated with lower thresholds and increased excitability, consistent with TRN neurons performing as coincidence detectors. On the other hand the presence of action potentials preceding any given spike was associated with more depolarized thresholds. The phase-plane trajectory of the action potential showed somato-dendritic propagation, but no obvious axon initial segment component, prominent in other neuronal classes and allegedly responsible for the high onset speed. Overall, our results suggest that TRN neurons could flexibly integrate synaptic inputs to discharge action potentials over wide voltage ranges, and perform as coincidence detectors and temporal integrators, supported by a dynamic action potential threshold.

  17. Of the clean development mechanism to the program of activities: an analysis of the bio diesel and wind energy uses in Brazil; Do mecanismo de desenvolvimento limpo ao programa de atividades: uma analise do uso do biodiesel e da energia eolica no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Rocha, Mayra Jupyara Braga

    2009-05-15

    The current actions of economic and industrial activities have resulted in increase of the concentration of greenhouse gases in the atmosphere since 1750. According to IPCC (2007) this alteration can increase the average temperature in the planet between 1,8 and 4,0 deg C up to 2100. The climate changes and the global warming are the most complicated environmental questions of our time and the actions took now will have effect on the future generations. In this context, a series of world-wide conferences and diverse scientific quarrels had occurred throughout the last decade, which culminated in the most important multilateral agreement firmed on climate changes, the Kyoto Protocol, signed in 1997. The Protocol is a landmark in the attempts of mitigation of the climate changes, since it established the commitment of the industrialized countries with emissions reduction targets of 5,2% to the level of 1990 emissions. To achieve such targets these countries count on three flexibilization mechanisms provided by the Kyoto Protocol: Joint implementation, Emission Trading and the Clean Development Mechanism (CDM) that it will be object of this study. The objective of this thesis is to carry through an evaluation of the CDM since its conception until the current days, searching to identify its dynamics and the main inherent gaps of this instrument and finally present two case studies of the bio diesel and wind energy uses in Brazil. (author)

  18. Active action potential propagation but not initiation in thalamic interneuron dendrites

    Science.gov (United States)

    Casale, Amanda E.; McCormick, David A.

    2012-01-01

    Inhibitory interneurons of the dorsal lateral geniculate nucleus of the thalamus modulate the activity of thalamocortical cells in response to excitatory input through the release of inhibitory neurotransmitter from both axons and dendrites. The exact mechanisms by which release can occur from dendrites are, however, not well understood. Recent experiments using calcium imaging have suggested that Na/K based action potentials can evoke calcium transients in dendrites via local active conductances, making the back-propagating action potential a candidate for dendritic neurotransmitter release. In this study, we employed high temporal and spatial resolution voltage-sensitive dye imaging to assess the characteristics of dendritic voltage deflections in response to Na/K action potentials in interneurons of the mouse dorsal lateral geniculate nucleus. We found that trains or single action potentials elicited by somatic current injection or local synaptic stimulation led to action potentials that rapidly and actively back-propagated throughout the entire dendritic arbor and into the fine filiform dendritic appendages known to release GABAergic vesicles. Action potentials always appeared first in the soma or proximal dendrite in response to somatic current injection or local synaptic stimulation, and the rapid back-propagation into the dendritic arbor depended upon voltage-gated sodium and TEA-sensitive potassium channels. Our results indicate that thalamic interneuron dendrites integrate synaptic inputs that initiate action potentials, most likely in the axon initial segment, that then back-propagate with high-fidelity into the dendrites, resulting in a nearly synchronous release of GABA from both axonal and dendritic compartments. PMID:22171033

  19. Genuine participation in participant-centred research initiatives: the rhetoric and the potential reality.

    Science.gov (United States)

    Feeney, Oliver; Borry, Pascal; Felzmann, Heike; Galvagni, Lucia; Haukkala, Ari; Loi, Michele; Nordal, Salvör; Rakic, Vojin; Riso, Brígida; Sterckx, Sigrid; Vears, Danya

    2018-04-01

    The introduction of Web 2.0 technology, along with a population increasingly proficient in Information and Communications Technology (ICT), coupled with the rapid advancements in genetic testing methods, has seen an increase in the presence of participant-centred research initiatives. Such initiatives, aided by the centrality of ICT interconnections, and the ethos they propound seem to further embody the ideal of increasing the participatory nature of research, beyond what might be possible in non-ICT contexts alone. However, the majority of such research seems to actualise a much narrower definition of 'participation'-where it is merely the case that such research initiatives have increased contact with participants through ICT but are otherwise non-participatory in any important normative sense. Furthermore, the rhetoric of participant-centred initiatives tends to inflate this minimalist form of participation into something that it is not, i.e. something genuinely participatory, with greater connections with both the ICT-facilitated political contexts and the largely non-ICT participatory initiatives that have expanded in contemporary health and research contexts. In this paper, we highlight that genuine (ICT-based) 'participation' should enable a reasonable minimum threshold of participatory engagement through, at least, three central participatory elements: educative, sense of being involved and degree of control. While we agree with criticisms that, at present, genuine participation seems more rhetoric than reality, we believe that there is clear potential for a greater ICT-facilitated participatory engagement on all three participatory elements. We outline some practical steps such initiatives could take to further develop these elements and thereby their level of ICT-facilitated participatory engagement.

  20. Non-lethal heat treatment of cells results in reduction of tumor initiation and metastatic potential

    International Nuclear Information System (INIS)

    Kim, Yoo-Shin; Lee, Tae Hoon; O'Neill, Brian E.

    2015-01-01

    Non-lethal hyperthermia is used clinically as adjuvant treatment to radiation, with mixed results. Denaturation of protein during hyperthermia treatment is expected to synergize with radiation damage to cause cell cycle arrest and apoptosis. Alternatively, hyperthermia is known to cause tissue level changes in blood flow, increasing the oxygenation and radiosensitivity of often hypoxic tumors. In this study, we elucidate a third possibility, that hyperthermia alters cellular adhesion and mechanotransduction, with particular impact on the cancer stem cell population. We demonstrate that cell heating results in a robust but temporary loss of cancer cell aggressiveness and metastatic potential in mouse models. In vitro, this heating results in a temporary loss in cell mobility, adhesion, and proliferation. Our hypothesis is that the loss of cellular adhesion results in suppression of cancer stem cells and loss of tumor virulence and metastatic potential. Our study suggests that the metastatic potential of cancer is particularly reduced by the effects of heat on cellular adhesion and mechanotransduction. If true, this could help explain both the successes and failures of clinical hyperthermia, and suggest ways to target treatments to those who would most benefit. - Highlights: • Non-lethal hyperthermia treatment of cancer cells is shown to cause a reduction in rates of tumor initiation and metastasis. • Dynamic imaging of cells during heat treatment shows temporary changes in cell shape, cell migration, and cell proliferation. • Loss of adhesion may lead to the observed effect, which may disproportionately impact the tumor initiating cell fraction. • Loss or suppression of the tumor initiating cell fraction results in the observed loss of metastatic potential in vivo. • This result may lead to new approaches to synergizing hyperthermia with surgery, radiation, and chemotherapy

  1. Non-lethal heat treatment of cells results in reduction of tumor initiation and metastatic potential

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yoo-Shin; Lee, Tae Hoon; O' Neill, Brian E., E-mail: BEOneill@houstonmethodist.org

    2015-08-14

    Non-lethal hyperthermia is used clinically as adjuvant treatment to radiation, with mixed results. Denaturation of protein during hyperthermia treatment is expected to synergize with radiation damage to cause cell cycle arrest and apoptosis. Alternatively, hyperthermia is known to cause tissue level changes in blood flow, increasing the oxygenation and radiosensitivity of often hypoxic tumors. In this study, we elucidate a third possibility, that hyperthermia alters cellular adhesion and mechanotransduction, with particular impact on the cancer stem cell population. We demonstrate that cell heating results in a robust but temporary loss of cancer cell aggressiveness and metastatic potential in mouse models. In vitro, this heating results in a temporary loss in cell mobility, adhesion, and proliferation. Our hypothesis is that the loss of cellular adhesion results in suppression of cancer stem cells and loss of tumor virulence and metastatic potential. Our study suggests that the metastatic potential of cancer is particularly reduced by the effects of heat on cellular adhesion and mechanotransduction. If true, this could help explain both the successes and failures of clinical hyperthermia, and suggest ways to target treatments to those who would most benefit. - Highlights: • Non-lethal hyperthermia treatment of cancer cells is shown to cause a reduction in rates of tumor initiation and metastasis. • Dynamic imaging of cells during heat treatment shows temporary changes in cell shape, cell migration, and cell proliferation. • Loss of adhesion may lead to the observed effect, which may disproportionately impact the tumor initiating cell fraction. • Loss or suppression of the tumor initiating cell fraction results in the observed loss of metastatic potential in vivo. • This result may lead to new approaches to synergizing hyperthermia with surgery, radiation, and chemotherapy.

  2. Transient debris freezing and potential wall melting during a severe reactivity initiated accident experiment

    International Nuclear Information System (INIS)

    El-Genk, M.S.; Moore, R.L.

    1981-01-01

    It is important to light water reactor (LWR) safety analysis to understand the transient freezing of molten core debris on cold structures following a hypothetical core meltdown accident. The purpose of this paper is to (a) present the results of a severe reactivity initiated accident (RIA) in-pile experiment with regard to molten debris distribution and freezing following test fuel rod failure, (b) analyze the transient freezing of molten debris (primarily a mixture of UO/sub 2/ fuel and Zircaloy cladding) deposited on the inner surface of the test shroud wall upon rod failure, and (c) assess the potential for wall melting upon being contacted by the molten debris. 26 refs

  3. Initial scoping of GHG emissions trading potential in Alberta : CABREE discussion paper

    International Nuclear Information System (INIS)

    Armstrong, R.

    2002-03-01

    The past five years have seen the emergence of the concept of emissions trading for greenhouse gases, which would make possible a reduction of the costs required to meet emissions targets agreed upon under the Kyoto Protocol. Emissions trading potential and initial scoping in Alberta is examined in this document, with a special emphasis placed on greenhouse gases. The design of a system, encompassing the theory underlying the mechanism, the current developments, issues of importance in this context, as well as the potential for inclusion of other sectors in Alberta were also discussed. For the purpose of this document, emissions trading was defined as one party reducing its emissions levels then transferring the ownership of that reduction to another party who can then purchase this reduction to assist in meeting its own emissions target. Emission trading can be divided into two basic types called Cap and Trade, and Baseline and Credit. Market creation and behaviour, and regulatory behaviour are factors that can render a trading system more feasible. It is important to analyze the goals before designing the specifics of the system. The incorporation of the various sectors of the economy of Alberta would be affected by their unique features. The greatest promise for emissions trading in Alberta is shown by the energy sector. The percentage of emissions covered, the number of participants, the economic effectiveness are all criteria that affect the performance of any system. figs

  4. South Africa's national REDD+ initiative: assessing the potential of the forestry sector on climate change mitigation

    International Nuclear Information System (INIS)

    Rahlao, Sebataolo; Mantlana, Brian; Winkler, Harald; Knowles, Tony

    2012-01-01

    Reducing emissions from deforestation and forest degradation in developing countries (REDD+) is regarded by its proponents as one of the more efficient and cost effective ways to mitigate climate change. There was further progress toward the implementation of this mechanism at the 16th Conference of Parties (COP) in Cancun in December 2010. Many countries in southern African, including South Africa, have not been integrated (do not participate) into the UN-REDD+ programme, probably due to their low forest cover and national rates of deforestation. This paper discusses the potential contribution of REDD+ activities to the South African Government's pledge of reducing national greenhouse gas (GHG) emissions by 34% below business as usual by 2020. A number of issues such as complex land tenure system, limited forest cover and other conflicting environmental issues present challenges for REDD+ in South Africa. Despite these genuine concerns, REDD+ remains a practical strategy to contribute to climate change mitigation for South Africa. The paper raises the need for development of a variety of emission reduction programmes – not only in the energy sector. The paper also assesses several national options and opportunities towards a working REDD+ mechanism. It concludes by identifying key mechanisms for moving forward to prepare for REDD+ actions in South Africa and raises the urgent need for national dialogue between stakeholders and institutions to evaluate the feasibility of making use of the mechanism in South Africa and the Southern African Development Cooperation (SADC) region. The paper further addresses possible synergies and conflicts between the national climate change and forestry policies towards REDD+ development. It suggests that REDD+ should be part of the national dialogue on policy to respond to climate change and should be integrated into the national flagship programmes that the national climate change white paper seeks to implement. A multiple

  5. Characteristics of the potential crop of raw materials for biodiesel and its adoption by family farms; Caracteristicas das potenciais culturas materias-primas do biodiesel e sua adocao pela agricultura familiar

    Energy Technology Data Exchange (ETDEWEB)

    Sluszz, Thaisy [Universidade Federal do Rio Grande do Sul (CEPAN/UFRGS), Porto Alegre, RS (Brazil). Centro de Estudos e Pesquisas em Agronegocios. Programa de Pos-Graduacao em Agronegocios], Email: thaisy@terra.com.br; Machado, Joao Armando Dessimon [Universidade Federal do Rio Grande do Sul (PGDR/CEPAN/UFRGS), Porto Alegre, RS (Brazil). Centro de Estudos e Pesquisas em Agronegocios], Email: joao.dessimon@ufrgs.br

    2006-07-01

    Beyond the economic advantages and the ambient benefits, the production of bio diesel in wide scale will be important instrument of generation of income in the agricultural way, with significant impact on familiar agriculture. One of the biggest motivations for the production of this alternative fuel was given by the federal government by means of the 'Social Combustible Stamp', that it foresees that producing industries buy deriving raw materials of bio diesel of familiar agriculture. Several are the viable cultures for the small property, thus being, in this article become an analysis of the potentialities of each culture raw material of biodiesel, to be produced for familiar agriculture in small properties, in the different Brazilian regions. The exploration research was used that it aimed at to provide to more familiarity with the question biodiesel x familiar agriculture and involved bibliographical survey and interviews the specialists. Several are the alternatives of cultivates with positive agronomic potential that can promote the inclusion of familiar agriculture in the chain productive of biodiesel, taking in consideration the characteristics of each Brazilian region, being the oil plants of bigger prominence: dende, coconut, babacu, sunflower, canola, castor, tame nut and sesame. (author)

  6. HIV-1 reverse transcription initiation: a potential target for novel antivirals?

    NARCIS (Netherlands)

    Abbink, Truus E. M.; Berkhout, Ben

    2008-01-01

    Reverse transcription is an essential step in the retroviral life cycle, as it converts the genomic RNA into DNA. In this review, we describe recent developments concerning the initiation step of this complex, multi-step reaction. During initiation of reverse transcription, a cellular tRNA primer is

  7. Bio Diesel An Alternative Vehicles Fuel; Analytical View

    International Nuclear Information System (INIS)

    El Banna, S.; El Deen, O.N.

    2004-01-01

    Transesterification of a vegetable oil was conducted as early as 1853, by scientists E. Duffy and J. Patrick, many years before the first diesel engine became functional(1). Rudolf Diesel's prime model, a single 10 ft (3 m) iron cylinder with a flywheel at its base, ran on its own power for the first time in Augsburg, Germany on August 10, 1893(2). Diesel later demonstrated his engine at the World Fair in Paris, France in 1898. This engine stood as an example of Diesel's vision because it was powered by peanut oil-a bio fuel. He believed that the utilization of a biomass fuel was the real future of his engine. In a 1912 speech, Rudolf Diesel said, (I) t he use of vegetable oils for engine fuels may seem insignificant today, but such oils may become, in the course of time, as important as petroleum and the coal-tar products of the present time. Rudolf Diesel was not the only inventor to believe that biomass fuels would be the mainstay of the transportation industry. Henry Ford designed his automobiles, beginning with the 1908 Model T(1), to use ethanol. Ford was so convinced that renewable resources were the key to the success of his automobiles that he built a plant to make ethanol in the Midwest and formed a partnership with Standard Oil to sell it in their distributing stations

  8. Studies on the tumor initiation/promotion potential of six middle distillates (MDs) in mouse skin.

    Science.gov (United States)

    Jungen, H; Mellert, W; Wenzel-Hartung, R

    1995-08-01

    Six middle distillates (MDs) were tested for tumor initiating/promoting activity after application to the skin of 30 male CD-1 (ICR) BR mice per group. As the control, 7,12-dimethylbenz[a]-anthracene (DMBA) was used for initiation followed by 12-O-tetradecanoylphorbol-13-acetate (TPA) for promotion. For assessing the tumor-initiating activity, 50 microliters of neat MDs was administered for 5 days with subsequent TPA promotion. In the promotion bioassay, after DMBA initiation 50 microliters of the neat MDs was administered twice weekly until Week 28. For the examination of complete carcinogenic activity, one MD was given without DMBA initiation. Hyperkeratosis, hyperplasia, and dermal inflammation, occurring during the initiation with the MDs, were completely reversible during the 2-week treatment-free period after initiation. Similar skin findings were observed during promotion with the MDs. Regarding the number of affected animals and the severity of the response, TPA was more irritating than the MDs. The initiation study revealed skin tumors for the DMBA/TPA control (30/30), MD 57,389 (14/30), MD 57,396 (5/30), MD 57,383 (4/30) and MD 57,324 (2/30). The promotion study revealed tumor induction by MDs 57,389 (9/30), 57,324 (1/30), 57,393 (1/30), and 57,396 (1/30). Two of 30 animals treated with MD 57,389 developed tumors without DMBA initiation thus indicating that it also is a complete carcinogen. MD 57,399 caused neither initiating nor promoting effects. The tumors observed were diagnosed histopathologically predominantly as squamous cell papillomas.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. Study of Hot Salt Stress Corrosion Crack Initiation of Alloy IMI 834 by using DC Potential Drop Method

    Energy Technology Data Exchange (ETDEWEB)

    Pustode, Mangesh D. [Bharat Forge Ltd., Pune (India); Dewangan, Bhupendra [Tata Steel, Jamshedpur (India); Raja, V. S. [Indian Institute of Technology Bombay, Mumbai (India); Paulose, Neeta; Babu, Narendra [Gas Turbine Research Establishment (GTRE), Bangalore (India)

    2016-10-15

    DC potential drop technique was employed during the slow strain rate tests to study the hot salt stress corrosion crack (HSSCC) initiation at 300 and 400 ℃. Threshold stresses for HSSCC initiation were found to about 88 % of the yield strength at both temperatures, but the time from crack initiation to final failure (Δtscc) decreased significantly with temperature, which reflects larger tendency for brittle fracture and secondary cracking. The brittle fracture features consisted of transgranular cracking through the primary α grain and discontinuous faceted cracking through the transformed β grains.

  10. Estimating Renewable Energy Economic Potential in the United States: Methodology and Initial Results

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Austin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Beiter, Philipp [National Renewable Energy Lab. (NREL), Golden, CO (United States); Heimiller, Donna [National Renewable Energy Lab. (NREL), Golden, CO (United States); Davidson, Carolyn [National Renewable Energy Lab. (NREL), Golden, CO (United States); Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Melius, Jennifer [National Renewable Energy Lab. (NREL), Golden, CO (United States); Lopez, Anthony [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hettinger, Dylan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mulcahy, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Porro, Gian [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-08-01

    The report describes a geospatial analysis method to estimate the economic potential of several renewable resources available for electricity generation in the United States. Economic potential, one measure of renewable generation potential, is defined in this report as the subset of the available resource technical potential where the cost required to generate the electricity (which determines the minimum revenue requirements for development of the resource) is below the revenue available in terms of displaced energy and displaced capacity.

  11. Using Empirical Data to Estimate Potential Functions in Commodity Markets: Some Initial Results

    Science.gov (United States)

    Shen, C.; Haven, E.

    2017-12-01

    This paper focuses on estimating real and quantum potentials from financial commodities. The log returns of six common commodities are considered. We find that some phenomena, such as the vertical potential walls and the time scale issue of the variation on returns, also exists in commodity markets. By comparing the quantum and classical potentials, we attempt to demonstrate that the information within these two types of potentials is different. We believe this empirical result is consistent with the theoretical assumption that quantum potentials (when embedded into social science contexts) may contain some social cognitive or market psychological information, while classical potentials mainly reflect `hard' market conditions. We also compare the two potential forces and explore their relationship by simply estimating the Pearson correlation between them. The Medium or weak interaction effect may indicate that the cognitive system among traders may be affected by those `hard' market conditions.

  12. Effects of rocuronium and vecuronium on initial rundown of endplate potentials in the isolated phrenic nerve diaphragm preparation of rats

    OpenAIRE

    Li, Jun; Liu, Yong-Qin; Zhang, Han-Ting

    2013-01-01

    Rocuronium and vecuronium, two non-depolarizing neuromuscular blockers, have been widely used in surgery procedures. However, their electrophysiological properties need to be more widely explored. We examined the effects of rocuronium and vecuronium on initial rundown of endplate potential amplitudes in the non-uniform stretched muscle preparation of the rat isolated phrenic nerve diaphragm. More specifically, the endplate potentials were recorded with one microelectrode from a single endplat...

  13. Initial phases of design-based research into the educational potentials of NAO-robots

    DEFF Research Database (Denmark)

    Majgaard, Gunver; Bertel, Lykke Brogaard

    2014-01-01

    In this paper, we describe our initial research, using the humanoid robot NAO in primary and secondary schools. How does a programmable humanoid enrich teaching and how do we prepare the teachers? Ten school classes are using the robot for creative programming. So far we have experienced...... that the robot enriches the learning processes by combining the auditory, visual and kinaesthetic modalities....

  14. Estimating Renewable Energy Economic Potential in the United States. Methodology and Initial Results

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Austin; Beiter, Philipp; Heimiller, Donna; Davidson, Carolyn; Denholm, Paul; Melius, Jennifer; Lopez, Anthony; Hettinger, Dylan; Mulcahy, David; Porro, Gian

    2016-08-01

    This report describes a geospatial analysis method to estimate the economic potential of several renewable resources available for electricity generation in the United States. Economic potential, one measure of renewable generation potential, may be defined in several ways. For example, one definition might be expected revenues (based on local market prices) minus generation costs, considered over the expected lifetime of the generation asset. Another definition might be generation costs relative to a benchmark (e.g., a natural gas combined cycle plant) using assumptions of fuel prices, capital cost, and plant efficiency. Economic potential in this report is defined as the subset of the available resource technical potential where the cost required to generate the electricity (which determines the minimum revenue requirements for development of the resource) is below the revenue available in terms of displaced energy and displaced capacity. The assessment is conducted at a high geospatial resolution (more than 150,000 technology-specific sites in the continental United States) to capture the significant variation in local resource, costs, and revenue potential. This metric can be a useful screening factor for understanding the economic viability of renewable generation technologies at a specific location. In contrast to many common estimates of renewable energy potential, economic potential does not consider market dynamics, customer demand, or most policy drivers that may incent renewable energy generation.

  15. Efficient Procedure to Compute the Microcanonical Volume of Initial Conditions that Lead to Escape Trajectories from a Multidimensional Potential Well

    NARCIS (Netherlands)

    Waalkens, Holger; Burbanks, Andrew; Wiggins, Stephen

    2005-01-01

    A procedure is presented for computing the phase space volume of initial conditions for trajectories that escape or ‘‘react’’ from a multidimensional potential well. The procedure combines a phase space transition state theory, which allows one to construct dividing surfaces that are free of local

  16. Panorama 2007: Potential biomass mobilization for bio-fuel production worldwide, in Europe and in France

    International Nuclear Information System (INIS)

    Lorne, D.

    2007-01-01

    One key factor in ensuring the success of bio-fuel technologies, which are expected to see high growth, is the availability of biomass resources. Although the targets set in Europe and France for the replacement of petroleum products in the transport sector by 2010 can be met by converting farm surpluses into biofuels, in order to proceed further, it will be necessary to mobilize a resource that is more abundant and potentially less costly: ligno-cellulosic materials, i.e. wood or straw. The future of biofuels depends on establishing the much-awaited 'second generation' bio-fuel pathways able to convert ligno-cellulosic materials to ethanol, bio-diesel and bio-kerosene. (author)

  17. GEOGRAPHIC INFORMATION SYSTEMS AND APPLIED ECONOMICS: AN INITIAL DISCUSSION OF POTENTIAL APPLICATIONS AND CONTRIBUTIONS

    OpenAIRE

    Taupier, Richard; Willis, Cleve E.

    1994-01-01

    Geographic Information Systems (GIS) are becoming increasingly important to virtually all of the natural and social sciences. Applied economists will find that GIS can make valuable contributions to many of the problems with which they are concerned. Moreover, a great deal of the science behind GIS technology would benefit from the contributions of applied economists. This paper presents some initial suggestions for the ways in which GIS may be important to economics and the GIS related issue...

  18. Potential savings of harmonising hospital and community formularies for chronic disease medications initiated in hospital.

    Directory of Open Access Journals (Sweden)

    Lauren Lapointe-Shaw

    Full Text Available Hospitals in Canada manage their formularies independently, yet many inpatients are discharged on medications which will be purchased through publicly-funded programs. We sought to determine how much public money could be saved on chronic medications if hospitals promoted the initiation of agents with the lowest outpatient formulary prices.We used administrative databases for the province of Ontario to identify patients initiated on a proton pump inhibitor (PPI, angiotensin-converting enzyme (ACE inhibitor or angiotensin receptor blocker (ARB following hospital admission from April 1(st 2008-March 31(st 2009. We assessed the cost to the Ontario Drug Benefit Program (ODB over the year following initiation and determined the cost savings if prescriptions were substituted with the least expensive agent in each class.The cost for filling all PPI, ACE inhibitor and ARB prescriptions was $ 2.48 million, $968 thousand and $325 thousand respectively. Substituting the least expensive agent could have saved $1.16 million (47% for PPIs, $162 thousand (17% for ACE inhibitors and $14 thousand (4% for ARBs over the year following discharge.In a setting where outpatient prescriptions are publicly funded, harmonising outpatient formularies with inpatient therapeutic substitution resulted in modest cost savings and may be one way to control rising pharmaceutical costs.

  19. Local, organic food initiatives and their potentials for transforming the conventional food system

    Directory of Open Access Journals (Sweden)

    Geir Lieblein

    2005-05-01

    Full Text Available L’objectif de cet article est de discuter l’importance des initiatives locales dans la distribution de produits biologiques. Le sujet est abordé d’une part en fonction de la relation entre ce type d’initiatives et le système agroalimentaire conventionnel et d’autre part en fonction de la possibilité du développement d’un système agroalimentaire plus durable. Basé sur trois études scandinaves, concernant des produits biologiques en Norvège et au Danemark, cet article souligne le fait que les différents acteurs intreviewés jouent à la fois sur le tableau du local et du biologique et sur le tableau du conventionnel. En dépit de différences structurelles distinctes, les deux systèmes, et les conventions qui leur sont rattachées, s’influencent mutuellement. Afin de mettre au point une agriculture plus durable, il semble donc important de mettre en valeur le fondement global de l’agriculture écologique, qui repose non seulement sur des valeurs biologiques et locales, mais encore sur des aspects économiques, sociaux et culturels qui doivent être pris en considération.The aim of this article is to discuss the importance of local initiatives for distribution of organic food. This subject is discussed both in relation to how such initiatives may affect the overall conventional food system and the possible implications for development of a more sustainable food system. The article is based on findings from three different cases of local, organic food in Norway and Denmark. We found that actors within the cases are both involved with local, organic food initiatives and at the same time part of the overall conventional food system. Even though there are distinctive structural differences between these distribution systems, they mutually affect each other. This means that conventions normally associated with local, organic food systems may ‘rub off’ to the conventional food system and vice versa. In order to develop

  20. Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons.

    Science.gov (United States)

    Battefeld, Arne; Tran, Baouyen T; Gavrilis, Jason; Cooper, Edward C; Kole, Maarten H P

    2014-03-05

    Rapid energy-efficient signaling along vertebrate axons is achieved through intricate subcellular arrangements of voltage-gated ion channels and myelination. One recently appreciated example is the tight colocalization of K(v)7 potassium channels and voltage-gated sodium (Na(v)) channels in the axonal initial segment and nodes of Ranvier. The local biophysical properties of these K(v)7 channels and the functional impact of colocalization with Na(v) channels remain poorly understood. Here, we quantitatively examined K(v)7 channels in myelinated axons of rat neocortical pyramidal neurons using high-resolution confocal imaging and patch-clamp recording. K(v)7.2 and 7.3 immunoreactivity steeply increased within the distal two-thirds of the axon initial segment and was mirrored by the conductance density estimates, which increased from ~12 (proximal) to 150 pS μm(-2) (distal). The axonal initial segment and nodal M-currents were similar in voltage dependence and kinetics, carried by K(v)7.2/7.3 heterotetramers, 4% activated at the resting membrane potential and rapidly activated with single-exponential time constants (~15 ms at 28 mV). Experiments and computational modeling showed that while somatodendritic K(v)7 channels are strongly activated by the backpropagating action potential to attenuate the afterdepolarization and repetitive firing, axonal K(v)7 channels are minimally recruited by the forward-propagating action potential. Instead, in nodal domains K(v)7.2/7.3 channels were found to increase Na(v) channel availability and action potential amplitude by stabilizing the resting membrane potential. Thus, K(v)7 clustering near axonal Na(v) channels serves specific and context-dependent roles, both restraining initiation and enhancing conduction of the action potential.

  1. Morphological Characterization of the Action Potential Initiation Segment in GnRH Neuron Dendrites and Axons of Male Mice.

    Science.gov (United States)

    Herde, Michel K; Herbison, Allan E

    2015-11-01

    GnRH neurons are the final output neurons of the hypothalamic network controlling fertility in mammals. In the present study, we used ankyrin G immunohistochemistry and neurobiotin filling of live GnRH neurons in brain slices from GnRH-green fluorescent protein transgenic male mice to examine in detail the location of action potential initiation in GnRH neurons with somata residing at different locations in the basal forebrain. We found that the vast majority of GnRH neurons are bipolar in morphology, elaborating a thick (primary) and thinner (secondary) dendrite from opposite poles of the soma. In addition, an axon-like process arising predominantly from a proximal dendrite was observed in a subpopulation of GnRH neurons. Ankyrin G immunohistochemistry revealed the presence of a single action potential initiation zone ∼27 μm in length primarily in the secondary dendrite of GnRH neurons and located 30 to 140 μm distant from the cell soma, depending on the type of process and location of the cell body. In addition to dendrites, the GnRH neurons with cell bodies located close to hypothalamic circumventricular organs often elaborated ankyrin G-positive axon-like structures. Almost all GnRH neurons (>90%) had their action potential initiation site in a process that initially, or ultimately after a hairpin loop, was coursing in the direction of the median eminence. These studies indicate that action potentials are initiated in different dendritic and axonal compartments of the GnRH neuron in a manner that is dependent partly on the neuroanatomical location of the cell body.

  2. E-cigarettes: Comparing the Possible Risks of Increasing Smoking Initiation with the Potential Benefits of Increasing Smoking Cessation.

    Science.gov (United States)

    Warner, Kenneth E; Mendez, David

    2018-03-29

    The public health community is divided regarding electronic cigarettes. Skeptics emphasize potential vaping-induced increases in smoking among children and possible health hazards for adults. Enthusiasts consider e-cigarettes much less dangerous than smoking and believe they increase adult smoking cessation. We compare potential health benefits and costs to put these two perspectives in context. Using a dynamic model that tracks the US adult population's smoking status and smoking-related deaths over time, we simulate the effects of vaping-induced smoking initiation and cessation on life-years saved or lost to the year 2070. The base case assumes that vaping annually increases smoking initiation by 2% and smoking cessation by 10%. Sensitivity analyses raise the initiation rate increase to 6% while decreasing the cessation rate increase to 5%. Sensitivity analyses also test vaping's reducing the health benefits of quitting smoking by 10%. With base-case assumptions, the population gains almost 3.3 million life-years by 2070. If all people who quit smoking by vaping lose 10% of the benefit of quitting smoking, the net life-year gain falls to 2.4 million. Under worst-case assumptions, in which vaping increases smoking initiation by 6% and cessation by 5%, and vaping-induced quitters lose 10% of the health benefits, the population gains over 580,000 life-years. Potential life-years gained as a result of vaping-induced smoking cessation are projected to exceed potential life-years lost due to vaping-induced smoking initiation. These results hold over a wide range of plausible parameters. Our analysis strongly suggests that the upside health benefit associated with e-cigarettes, in terms of their potential to increase adult smoking cessation, exceeds their downside risk to health as a result of their possibly increasing the number of youthful smoking initiators. Public messaging and policy should continue to strive to reduce young people's exposure to all nicotine and

  3. Axon initial segment Kv1 channels control axonal action potential waveform and synaptic efficacy

    NARCIS (Netherlands)

    Kole, Maarten H. P.; Letzkus, Johannes J.; Stuart, Greg J.

    2007-01-01

    Action potentials are binary signals that transmit information via their rate and temporal pattern. In this context, the axon is thought of as a transmission line, devoid of a role in neuronal computation. Here, we show a highly localized role of axonal Kv1 potassium channels in shaping the action

  4. Effect of initialization time on application potentiality of a ZnO thin film based LPG sensor

    Directory of Open Access Journals (Sweden)

    Parta Mitra

    2009-09-01

    Full Text Available A prototype electronic LPG (Liquid Petroleum Gas sensor based on zinc oxide (ZnO film has been fabricated. The objective of the present work was to investigate the importance of initialization time (also called warm-up time on the application potentiality of the ZnO based alarm. The role of sensor geometry on initialization time is presented. The electronic circuitry of the prototype LPG device alarm is discussed. It is shown that that the initialization time depends on the switch off time (or the time for which the sensor was kept idle. The resistive mode sensors can be fixed at 40% LEL (Lower Explosive Limit of LPG for safe operation.

  5. Potential impact on HIV incidence of higher HIV testing rates and earlier antiretroviral therapy initiation in MSM

    DEFF Research Database (Denmark)

    Phillips, Andrew N; Cambiano, Valentina; Miners, Alec

    2015-01-01

    count 350/μl. We investigated what would be required to reduce HIV incidence in MSM to below 1 per 1000 person-years (i.e. cost-effective. METHODS: A dynamic, individual-based simulation model was calibrated to multiple data sources...... with viral suppression to 80%, and it would be 90%, if ART is initiated at diagnosis. The scenarios required for such a policy to be cost-effective are presented. CONCLUSION: This analysis provides targets for the proportion of all HIV-positive MSM with viral suppression required to achieve substantial......BACKGROUND: Increased rates of testing, with early antiretroviral therapy (ART) initiation, represent a key potential HIV-prevention approach. Currently, in MSM in the United Kingdom, it is estimated that 36% are diagnosed by 1 year from infection, and the ART initiation threshold is at CD4 cell...

  6. Recessive Resistance to Plant Viruses: Potential Resistance Genes Beyond Translation Initiation Factors

    Directory of Open Access Journals (Sweden)

    Masayoshi Hashimoto

    2016-10-01

    Full Text Available The ability of plant viruses to propagate their genomes in host cells depends on many host factors. In the absence of an agrochemical that specifically targets plant viral infection cycles, one of the most effective methods for controlling viral diseases in plants is taking advantage of the host plant’s resistance machinery. Recessive resistance is conferred by a recessive gene mutation that encodes a host factor critical for viral infection. It is a branch of the resistance machinery and, as an inherited characteristic, is very durable. Moreover, recessive resistance may be acquired by a deficiency in a negative regulator of plant defense responses, possibly due to the autoactivation of defense signaling. Eukaryotic translation initiation factor (eIF 4E and eIF4G and their isoforms are the most widely exploited recessive resistance genes in several crop species, and they are effective against a subset of viral species. However, the establishment of efficient, recessive resistance-type antiviral control strategies against a wider range of plant viral diseases requires genetic resources other than eIF4Es. In this review, we focus on recent advances related to antiviral recessive resistance genes evaluated in model plants and several crop species. We also address the roles of next-generation sequencing and genome editing technologies in improving plant genetic resources for recessive resistance-based antiviral breeding in various crop species.

  7. Use of equilibrium constant expression for initial screening of potential antithyroid agents

    International Nuclear Information System (INIS)

    Fatima, I.; Nanawar, M.A.; Tasneem, A.

    2011-01-01

    Synthetic antithyroid agents act through inhibition of enzyme or by making stable charge transfer (CT) complex with iodine. Iodine acts as s-acceptor and the synthetic compound as n-donor. Study of CT complexation of various drugs with iodine using UV/visible spectroscopy has revealed a positive correlation between the formation constant (Kc) and in vivo an activity. Some alkyl derivatives of 9H-purine-6-thiol were synthesized and evaluated in vitro as well as in vivo for potential antithyroid effects. The compounds exhibited 1:1 charge transfer complexation with iodine and have quite high values of formation constants. The blood assays of rats treated with these compounds and histological study of the thyroid tissues indicated the hyperactivity of gland. These compounds are expected to have lesser side effects as the sulfa group, a cause of toxicity in many medicines, is blocked. Phenyl derivative proved to be the most potent antithyroid agent comparable with methimazole. (author)

  8. Initial Investigation into the Potential of CSP Industrial Process Heat for the Southwest United States

    Energy Technology Data Exchange (ETDEWEB)

    Kurup, Parthiv [National Renewable Energy Lab. (NREL), Golden, CO (United States); Turchi, Craig [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-11-01

    After significant interest in the 1970s, but relatively few deployments, the use of solar technologies for thermal applications, including enhanced oil recovery (EOR), desalination, and industrial process heat (IPH), is again receiving global interest. In particular, the European Union (EU) has been a leader in the use, development, deployment, and tracking of Solar Industrial Process Heat (SIPH) plants. The objective of this study is to ascertain U.S. market potential of IPH for concentrating collector technologies that have been developed and promoted through the U.S. Department of Energy's Concentrating Solar Power (CSP) Program. For this study, the solar-thermal collector technologies of interest are parabolic trough collectors (PTCs) and linear Fresnel (LF) systems.

  9. Oil Spills and Dispersants Can Cause the Initiation of Potentially Harmful Dinoflagellate Blooms ("Red Tides").

    Science.gov (United States)

    Almeda, Rodrigo; Cosgrove, Sarah; Buskey, Edward J

    2018-04-25

    After oil spills and dispersant applications the formation of red tides or harmful algal blooms (HABs) has been observed, which can cause additional negative impacts in areas affected by oil spills. However, the link between oil spills and HABs is still unknown. Here, we present experimental evidence that demonstrates a connection between oil spills and HABs. We determined the effects of oil, dispersant-treated oil, and dispersant alone on the structure of natural plankton assemblages in the Northern Gulf of Mexico. In coastal waters, large tintinnids and oligotrich ciliates, major grazers of phytoplankton, were negatively affected by the exposure to oil and dispersant, whereas bloom-forming dinoflagellates ( Prorocentrum texanum, P. triestinum, and Scrippsiella trochoidea) notably increased their concentration. The removal of key grazers due to oil and dispersant disrupts the predator-prey controls ("top-down controls") that normally function in plankton food webs. This disruption of grazing pressure opens a "loophole" that allows certain dinoflagellates with higher tolerance to oil and dispersants than their grazers to grow and form blooms when there are no growth limiting factors (e.g., nutrients). Therefore, oil spills and dispersants can act as disrupters of predator-prey controls in plankton food webs and as indirect inducers of potentially harmful dinoflagellate blooms.

  10. An Initial Assessment Of Potential Production Technologies For Epsilon-Metal Waste Forms

    International Nuclear Information System (INIS)

    Rohatgi, Aashish; Strachan, Denis M.

    2011-01-01

    This report examines and ranks a total of seven materials processing techniques that may be potentially utilized to consolidate the undissolved solids from nuclear fuel reprocessing into a low-surface area form. Commercial vendors of processing equipment were contacted and literature researched to gather information for this report. Typical equipment and their operation, corresponding to each of the seven techniques, are described in the report based upon the discussions and information provided by the vendors. Although the report does not purport to describe all the capabilities and issues of various consolidation techniques, it is anticipated that this report will serve as a guide by highlighting the key advantages and disadvantages of these techniques. The processing techniques described in this report were broadly classified into those that employed melting and solidification, and those in which the consolidation takes place in the solid-state. Four additional techniques were examined that were deemed impractical, but were included for completeness. The techniques were ranked based on criteria such as flexibility in accepting wide-variety of feed-stock (chemistry, form, and quantity), ease of long-term maintenance, hot cell space requirements, generation of additional waste streams, cost, and any special considerations. Based on the assumption of ∼2.5 L of waste to be consolidated per day, sintering based techniques, namely, microwave sintering, spark plasma sintering and hot isostatic pressing, were ranked as the top-3 choices, respectively. Melting and solidification based techniques were ranked lower on account of generation of volatile phases and difficulties associated with reactivity and containment of the molten metal.

  11. Reflection on Mobile Applications for Blood Pressure Management: A Systematic Review on Potential Effects and Initiatives.

    Science.gov (United States)

    Mohammadi, Reyhaneh; Ayatolahi Tafti, Movahhedeh; Hoveidamanesh, Soodabeh; Ghanavati, Reza; Pournik, Omid

    2018-01-01

    Ischemic heart disease and stroke have been considered as the first global leading cause of death in last decades [1]. Blood pressure (BP) management is one of the easiest ways suggested for preventing and controlling cardiovascular diseases before the patient develops complications and death-following outcomes. Appearance of technology advancements in the health system has motivated researchers and health providers to study its different aspects and applications in order to improve disease prevention and management. Following these efforts, mobile health (mHealth) technologies were presented to provide people with fast and easier-to-use services. Although there are some unsolved challenges, these technologies have become popular among many people. As an important part of mHealth, mobile applications (apps) have been the focused subject of many studies in the last decade. The objective of this systematic review is to assess the potential effects of mobile apps designed for BP management by scrutinizing the related studies. Search methods: We searched the following electronic databases in December 2016: Medline (PubMed), National Center for Biotechnology Information (NCBI), Cochrane Central Register of Controlled Trials (CENTRAL), PsycINFO, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Education Resources Information Center(ERIC), Web of Science, ProQuest, and Google Scholar. No language restriction and start point limitation were imposed. We included studies that evaluated and assessed mobile apps for BP management and related clinical trials that considered mobile app as the only difference between intervention and control groups. Two review authors applied the eligibility criteria, extracted data and assessed the quality of included studies. Literature search resulted in 13 included studies and 27 reviews. 12 records of 13 included studies identified as interventional studies. The review showed that the mobile apps may improve individual's BP

  12. Effect of potential waste constituents on the reactivity of Hanford ferrocyanide wastes: Diluent, catalyst, and initiator studies

    International Nuclear Information System (INIS)

    Scheele, R.D.; Johnston, J.W.; Tingey, J.M.; Burger, L.L.; Sell, R.L.

    1993-04-01

    During the 1980s, scientists at the Hanford Site began considering disposal options for wastes in underground storage tanks. As a result of safety concerns, it was determined that special consideration should be given to ferrocyanide-bearing wastes to ensure their continued safe storage. In addition, Westinghouse Hanford Company (WHC) chartered Pacific Northwest Laboratory (PNL) to determine the conditions necessary for vigorous reactions to occur in the Hanford Site ferrocyanide wastes. As part of those studies, PNL has evaluated the effects of selected potential waste constituents to determine how they might affect the reactivity of the wastes. The authors' investigations of the diluent, catalytic, or initiating effects of potential waste constituents included studies (1) to determine the effect of the oxidant-to-ferrocyanide ratio, (2) to establish the effect of sodium aluminate concentration, (3) to identify materials that could affect the explosivity of a mixture of sodium nickel ferricyanide (a potential aging product of ferrocyanide) and sodium nitrate and nitrite, (4) and to determine the effect of nickel sulfide concentration. They also conducted a thermal sensitivity study and analyzed the results to determine the relative behaviors of sodium nickel ferrocyanide and ferricyanide. A statistical evaluation of the time-to-explosion (TTX) test results from the catalyst and initiator screening study found that the ferricyanide reacted at a faster rate than did the ferrocyanide analog. The thermal analyses indicated that the ferricyanide form is more thermally sensitive, exhibiting exothermic behavior at a lower temperature than the ferrocyanide form. The increased thermal sensitivity of the ferricyanide, which is a potential oxidation product of ferrocyanide, relative to the ferrocyanide analog, does not support the hypothesis that aging independent of the reaction pathway will necessarily reduce the reaction hazard of ferrocyanide wastes

  13. Stabilization of the initial electrochemical potential for a metal-based potentiometric titration study of a biosorption process.

    Science.gov (United States)

    Naja, Ghinwa; Mustin, Christian; Volesky, Bohumil; Berthelin, Jacques

    2006-01-01

    An interactive metal-based potentiometric titration method has been developed using an ion selective electrode for studying the sorption of metal cations. The accuracy of this technique was verified by analyzing the metal sorption mechanism for the biomass of Rhizopus arrhizus fungus and diatomite, two dissimilar materials (organic and mineral, strong sorbent and weak sorbent) of a different order of cation exchange capacity. The problem of the initial electrochemical potential was addressed identifying the usefulness of a Na-sulfonic resin as a strong chelating agent applied before the beginning of sorption titration experiments so that the titration curves and the sorption uptake could be quantitatively compared. The resin stabilized the initial electrochemical potential to -405+/-5 mV corresponding to 2 micro gl(-1) of lead concentration in solution. The amounts of lead sorbed by R. arrhizus biomass and diatomite were 0.9 mmol g(-1) (C(e)=5.16 x 10(-2)mM) and 0.052 mmol g(-1) (C(e)=5.97 x 10(-2) mM), respectively. Lead sorption by the fungal biomass was pinpointed to at least two types of chemical active sites. The first type was distinguished by high reactivity and a low number of sites whereas the other was characterized by their higher number and lower reactivity.

  14. The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients

    Directory of Open Access Journals (Sweden)

    Joaquín Pérez-Guisado

    2013-01-01

    Full Text Available Objective. The aim of this study was to determine if early initiation of oral/enteral nutrition in burn patients minimizes the drop in fT3 levels, reduces the potential for euthyroid sick syndrome (ESS, and shortens the length of hospital stay (LHS. Subjects and Methods. We retrospectively evaluated the statistical association of serum fT3, fT4, and TSH at the first (2nd–5th day and second sample collection (9th–12th day after the burn injury in 152 burn patients. Three groups were established depending on time of initiation of the oral/enteral nutrition: 48 h after the injury (Group 3. Results. They were expressed as mean ± standard deviation. We found that LHS and the fT3 levels were statistically different in the 3 groups. The LHS (in days was, respectively, in each group, 16.77±4.56, 21.98±4.86, and 26.06±5.47. Despite the quantifiable drop in fT3, ESS was present only at the first sample collection (2.61±0.92 days in Group 3, but there was no group with ESS at the second sample collection (9.89±1.01 days. Our data suggest that early initiation of nutritional supplementation decreases the length of hospitalization and is associated with decreasing fT3 serum concentration depression. Conclusion. Early initiation of oral/enteral nutrition counteracts ESS and improves the LHS in burn patients.

  15. The potential association of later initiation of oral/enteral nutrition on euthyroid sick syndrome in burn patients.

    Science.gov (United States)

    Pérez-Guisado, Joaquín; de Haro-Padilla, Jesús M; Rioja, Luis F; Derosier, Leo C; de la Torre, Jorge I

    2013-01-01

    Objective. The aim of this study was to determine if early initiation of oral/enteral nutrition in burn patients minimizes the drop in fT3 levels, reduces the potential for euthyroid sick syndrome (ESS), and shortens the length of hospital stay (LHS). Subjects and Methods. We retrospectively evaluated the statistical association of serum fT3, fT4, and TSH at the first (2nd-5th day) and second sample collection (9th-12th day) after the burn injury in 152 burn patients. Three groups were established depending on time of initiation of the oral/enteral nutrition: 48 h after the injury (Group 3). Results. They were expressed as mean ± standard deviation. We found that LHS and the fT3 levels were statistically different in the 3 groups. The LHS (in days) was, respectively, in each group, 16.77 ± 4.56, 21.98 ± 4.86, and 26.06 ± 5.47. Despite the quantifiable drop in fT3, ESS was present only at the first sample collection (2.61 ± 0.92 days) in Group 3, but there was no group with ESS at the second sample collection (9.89 ± 1.01 days). Our data suggest that early initiation of nutritional supplementation decreases the length of hospitalization and is associated with decreasing fT3 serum concentration depression. Conclusion. Early initiation of oral/enteral nutrition counteracts ESS and improves the LHS in burn patients.

  16. Fusion imaging of computed tomographic pulmonary angiography and SPECT ventilation/perfusion scintigraphy: initial experience and potential benefit

    International Nuclear Information System (INIS)

    Harris, Benjamin; Bailey, Dale; Roach, Paul; Bailey, Elizabeth; King, Gregory

    2007-01-01

    The objective of this study was to examine the feasibility of fusing ventilation and perfusion data from single-photon emission computed tomography (SPECT) ventilation perfusion (V/Q) scintigraphy together with computed tomographic pulmonary angiography (CTPA) data. We sought to determine the accuracy of this fusion process. In addition, we correlated the findings of this technique with the final clinical diagnosis. Thirty consecutive patients (17 female, 13 male) who had undergone both CTPA and SPECT V/Q scintigraphy during their admission for investigation of potential pulmonary embolism were identified retrospectively. Image datasets from these two modalities were co-registered and fused using commercial software. Accuracy of the fusion process was determined subjectively by correlation between modalities of the anatomical boundaries and co-existent pleuro-parenchymal abnormalities. In all 30 cases, SPECT V/Q images were accurately fused with CTPA images. An automated registration algorithm was sufficient alone in 23 cases (77%). Additional linear z-axis scaling was applied in seven cases. There was accurate topographical co-localisation of vascular, parenchymal and pleural disease on the fused images. Nine patients who had positive CTPA performed as an initial investigation had co-localised perfusion defects on the subsequent fused CTPA/SPECT images. Three of the 11 V/Q scans initially reported as intermediate could be reinterpreted as low probability owing to co-localisation of defects with parenchymal or pleural pathology. Accurate fusion of SPECT V/Q scintigraphy to CTPA images is possible. This technique may be clinically useful in patients who have non-diagnostic initial investigations or in whom corroborative imaging is sought. (orig.)

  17. Corrosion of Steel in Concrete – Potential Monitoring and Electrochemical Impedance Spectroscopy during Corrosion Initiation and Propagation

    DEFF Research Database (Denmark)

    Küter, Andre; Mason, Thomas O.; Geiker, Mette Rica

    2005-01-01

    wires. The wires can act as both reference and counter electrode during EIS and, thus, no external electrode is required. The defined geometry solves reproducibility problems involved with application of an external reference electrode for EIS. Changes of the electromotive force (EMF) between rebar...... and titanium wires can be monitored immediately after preparation. The wire arrangement also allows investigation of local changes in the bulk mortar by EIS or by measuring the potential development of the titanium wires versus an external standard electrode. The specimen design was evaluated...... in an investigation on the effect of the steel quality and the steel surface properties on initiation and propagation of chloride-induced reinforcement corrosion. Besides untreated (as received) carbon rebars and stainless rebars, selected surface treatments and galvanization were investigated. The surface treatments...

  18. Potential for hydrogen-oxidizing chemolithoautotrophic and diazotrophic populations to initiate biofilm formation in oligotrophic, deep terrestrial subsurface waters.

    Science.gov (United States)

    Wu, Xiaofen; Pedersen, Karsten; Edlund, Johanna; Eriksson, Lena; Åström, Mats; Andersson, Anders F; Bertilsson, Stefan; Dopson, Mark

    2017-03-23

    Deep terrestrial biosphere waters are separated from the light-driven surface by the time required to percolate to the subsurface. Despite biofilms being the dominant form of microbial life in many natural environments, they have received little attention in the oligotrophic and anaerobic waters found in deep bedrock fractures. This study is the first to use community DNA sequencing to describe biofilm formation under in situ conditions in the deep terrestrial biosphere. In this study, flow cells were attached to boreholes containing either "modern marine" or "old saline" waters of different origin and degree of isolation from the light-driven surface of the earth. Using 16S rRNA gene sequencing, we showed that planktonic and attached populations were dissimilar while gene frequencies in the metagenomes suggested that hydrogen-fed, carbon dioxide- and nitrogen-fixing populations were responsible for biofilm formation across the two aquifers. Metagenome analyses further suggested that only a subset of the populations were able to attach and produce an extracellular polysaccharide matrix. Initial biofilm formation is thus likely to be mediated by a few bacterial populations which were similar to Epsilonproteobacteria, Deltaproteobacteria, Betaproteobacteria, Verrucomicrobia, and unclassified bacteria. Populations potentially capable of attaching to a surface and to produce extracellular polysaccharide matrix for attachment were identified in the terrestrial deep biosphere. Our results suggest that the biofilm populations were taxonomically distinct from the planktonic community and were enriched in populations with a chemolithoautotrophic and diazotrophic metabolism coupling hydrogen oxidation to energy conservation under oligotrophic conditions.

  19. Design, synthesis, and initial evaluation of D-glyceraldehyde crosslinked gelatin-hydroxyapatite as a potential bone graft substitute material

    Science.gov (United States)

    Florschutz, Anthony Vatroslav

    Utilization of bone grafts for the treatment of skeletal pathology is a common practice in orthopaedic, craniomaxillofacial, dental, and plastic surgery. Autogenous bone graft is the established archetype but has disadvantages including donor site morbidity, limited supply, and prolonging operative time. In order to avoid these and other issues, bone graft substitute materials are becoming increasingly prevalent among surgeons for reconstructing skeletal defects and arthrodesis applications. Bone graft substitutes are biomaterials, biologics, and guided tissue/bone regenerative devices that can be used alone or in combinations as supplements or alternatives to autogenous bone graft. There is a growing interest and trend to specialize graft substitutes for specific indications and although there is good rationale for this indication-specific approach, the development and utility of a more universal bone graft substitute may provide a better answer for patients and surgeons. The aim of the present research focuses on the design, synthesis, and initial evaluation of D-glyceraldehyde crosslinked gelatin-hydroxyapatite composites for potential use as a bone graft substitutes. After initial establishment of rational material design, gelatinhydroxyapatite scaffolds were fabricated with different gelatin:hydroxyapatite ratios and crosslinking concentrations. The synthesized scaffolds were subsequently evaluated on the basis of their swelling behavior, porosity, density, percent composition, mechanical properties, and morphology and further assessed with respect to cell-biomaterial interaction and biomineralization in vitro. Although none of the materials achieved mechanical properties suitable for structural graft applications, a reproducible material design and synthesis was achieved with properties recognized to facilitate bone formation. Select scaffold formulations as well as a subset of scaffolds loaded with recombinant human bone morphogenetic protein-2 were

  20. Non-Chemical Stressors and Cumulative Risk Assessment: An Overview of Current Initiatives and Potential Air Pollutant Interactions

    Science.gov (United States)

    Lewis, Ari S.; Sax, Sonja N.; Wason, Susan C.; Campleman, Sharan L.

    2011-01-01

    Regulatory agencies are under increased pressure to consider broader public health concerns that extend to multiple pollutant exposures, multiple exposure pathways, and vulnerable populations. Specifically, cumulative risk assessment initiatives have stressed the importance of considering both chemical and non-chemical stressors, such as socioeconomic status (SES) and related psychosocial stress, in evaluating health risks. The integration of non-chemical stressors into a cumulative risk assessment framework has been largely driven by evidence of health disparities across different segments of society that may also bear a disproportionate risk from chemical exposures. This review will discuss current efforts to advance the field of cumulative risk assessment, highlighting some of the major challenges, discussed within the construct of the traditional risk assessment paradigm. Additionally, we present a summary of studies of potential interactions between social stressors and air pollutants on health as an example of current research that supports the incorporation of non-chemical stressors into risk assessment. The results from these studies, while suggestive of possible interactions, are mixed and hindered by inconsistent application of social stress indicators. Overall, while there have been significant advances, further developments across all of the risk assessment stages (i.e., hazard identification, exposure assessment, dose-response, and risk characterization) are necessary to provide a scientific basis for regulatory actions and effective community interventions, particularly when considering non-chemical stressors. A better understanding of the biological underpinnings of social stress on disease and implications for chemical-based dose-response relationships is needed. Furthermore, when considering non-chemical stressors, an appropriate metric, or series of metrics, for risk characterization is also needed. Cumulative risk assessment research will benefit

  1. An Analysis of Current Energy Policy Initiatives in New Mexico. What are the Potential Impacts to the State's Water Resources?

    Science.gov (United States)

    Klise, G. T.; Hart, W. E.; Kobos, P. H.; Malczynski, L. A.; Tidwell, V. C.

    2008-12-01

    Population in New Mexico is increasing rapidly with recent projections showing that the state will add more than 1 million people by 2035. This growth will create a demand for additional energy and water supplies that have yet to be developed. New Mexico currently exports about 50% of the energy generated within the state to neighboring states, and existing power plants predominately utilize traditional fossil fuels such as coal, oil and natural gas. Because traditional electric generation technologies utilize large quantities of water, New Mexico can also be seen as exporting water for the benefit of electricity consumed in neighboring states. As it is, both surface water and groundwater supplies are stretched thin and these internal and external stresses stemming from population growth will have a substantial impact on the state's water resources. In 2004, the Governor laid out a plan to make New Mexico a "Clean Energy State" by implementing renewable portfolio standards, developing renewable energy transmission infrastructure, creating an alternative energy innovation fund and creating state specific tax credits for renewable energy production and manufacturing. Recent work in the National Energy-Water Roadmap has pointed out that certain renewable sources of energy utilize less water than traditional power plants, and technological fixes to existing power plants will result in less water consumption. If New Mexico carries out its energy initiative, what will be the impacts to the state's water resources? Will it be possible to meet competing demands for this water? These questions and others will be analyzed in a decision-support tool that can look at the connection between both the physical and economic systems to see what the tradeoffs might be as a result of specific policy decisions. The ability to plan for future energy needs and understanding potential impacts to the state's limited water resources will be an invaluable tool for decision-makers in New

  2. Pattern of language-related potential maps in cluster and noncluster initial consonants in consonant-vowel (CV syllables

    Directory of Open Access Journals (Sweden)

    Naiphinich Kotchabhakdi

    2006-09-01

    Full Text Available Mismatch negativity (MMN was used to investigate the processing of cluster and noncluster initial consonants in consonant vowel syllables in the human brain. The MMN was elicited by either syllable with cluster or noncluster initial consonant, phonetic contrasts being identical in both syllables. Compared to the noncluster consonant, the cluster consonant elicited a more prominent MMN. The MMN to the cluster consonant occurred later than that of the noncluster consonant. The topography of the mismatch responses showed clear left-hemispheric laterality in both syllables. However, the syllable with an initial noncluster consonant stimulus produced MMN maximum over the middle temporal gyrus, whereas maximum of the MMN activated by the syllable with initial cluster consonant was observed over the superior temporal gyrus. We suggest that the MMN component in consonant-vowel syllables is more sensitive to cluster compared to noncluster initial consonants. Spatial and temporal features of the cluster consonant indicate delayed activation of left-lateralized perisylvian cell assemblies that function as cortical memory traces of cluster initial consonant in consonant-vowel syllables.

  3. Global change impact on oxidative potential and toxicity of atmospheric particles from the East Mediterranean basin: the ARCHIMEDES initiative

    Science.gov (United States)

    Alleman, Laurent; Anthérieu, Sébastien; Baeza-Squiban, Armelle; Garçon, Guillaume; Lo Guidice, Jean-Marc; Hamonou, Eric; Öztürk, Fatma; Perdrix, Esperanza; Rudich, Yinon; Sciare, Jean; Sauvage, Stéphane

    2017-04-01

    Climate change (CC) has important social, economical and health implications, notably in accordance with variation in air pollution or microbiome modification and its related toxicity mechanisms. CC will have a strong influence on meteorology, inducing dryer and warmer conditions in some regions. The Mediterranean basin is foreseen as a hotspot for regional climate warming, favoring larger dust episodes, wild fire events, vegetation emissions and changes in air pollution physic-chemical characteristics due to enhanced photochemical reactivity. Increasing concentrations of biogenic volatile organic compounds (VOCs), ozone, and radicals will be associated with rising concentrations of secondary organic aerosols (SOA) and other oxidized aerosols. These expected changes in aerosol composition are currently studied within the international ChArMEx (Chemistry-aerosol Mediterranean Experiment) program, part of the interdisciplinary MISTRALS metaprogramme (Mediterranean Integrated STudies at Regional And Local Scales). According to the LIFE/MED-PARTICLES (LIFE) project, this might result in more adverse effects on health. However, toxicologists are far from having a detailed mechanistic knowledge of the quantitative causal relations between particles (PM) and health effects suggested by epidemiological evidences. Detailed toxicological studies looking at contrasted PM origins and chemical compositions are highly needed, particularly on strongly aged SOA suspected to increase the oxidative potential (OP) and to enhance the toxicity of airborne particles. Intensive researches onto the underlying mechanisms of inflammation started to describe the outlines of the intricate relationship between oxidative stress and inflammation. It is therefore, of great importance to better determine the OP of PM from contrasted surroundings, its relationship with CC through PM's physical, chemical and microbial characteristics, and its toxicological consequences within the lungs. Recently

  4. The White House BRAIN Initiative has the potential to further strengthen multidisciplinary research and training in psychology.

    Science.gov (United States)

    Flattau, Pamela

    2014-12-01

    Comments on the original article by Robiner et al. (see record 2014-07939-001) regarding psychologists in medical schools and academic medical center settings. The current authors also discuss how to advance training in psychology using the Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  5. The potential role of ribosomal protein S5 on cell cycle arrest and initiation of murine erythroleukemia cell differentiation.

    Science.gov (United States)

    Matragkou, Christina N; Papachristou, Eleni T; Tezias, Sotirios S; Tsiftsoglou, Asterios S; Choli-Papadopoulou, Theodora; Vizirianakis, Ioannis S

    2008-07-01

    Evidence now exists to indicate that some ribosomal proteins besides being structural components of the ribosomal subunits are involved in the regulation of cell differentiation and apoptosis. As we have shown earlier, initiation of erythroid differentiation of murine erythroleukemia (MEL) cells is associated with transcriptional inactivation of genes encoding ribosomal RNAs and ribosomal proteins S5 (RPS5) and L35a. In this study, we extended these observations and investigated whether transfection of MEL cells with RPS5 cDNA affects the onset of initiation of erythroid maturation and their entrance in cell cycle arrest. Stably transfected MEL cloned cells (MEL-C14 and MEL-C56) were established and assessed for their capacity to produce RPS5 RNA transcript and its translated product. The impact of RPS5 cDNA transfection on the RPS5 gene expression patterns and the accumulation of RPS5 protein in inducible transfected MEL cells were correlated with their ability to: (a) initiate differentiation, (b) enter cell cycle arrest at G(1)/G(0) phase, and (c) modulate the level of cyclin-dependent kinases CDK2, CDK4, and CDK6. The data presented indicate that deregulation of RPS5 gene expression (constitutive expression) affects RPS5 protein level and delays both the onset of initiation of erythroid maturation and entrance in cell cycle arrest in inducer-treated MEL cells. 2008 Wiley-Liss, Inc.

  6. Algae potential resource assessment for the energy and chemistry sectors in France by 2030

    International Nuclear Information System (INIS)

    Kerlero De Rosbo, Guillaume; Payen, Luc; Bernard, Olivier; Mairet, Francis; Grimaud, Ghjuvan; Delclaux, Etienne; Rey, David; Ras De Moncuit, Monique; Houdon, Aude-Claire; Gagnepain, Bruno; Gueudet, Alice; El Khamlichi, Aicha; Delalande, Claire; Eglin, Thomas; Pouet, Jean-Christophe; Allouche, Yohan; Lombard, Christophe; Mhiri, Tarek; Mazzenga, Anthony; Lasserre, Thomas; Potin, Philippe; Kaas, Raymond; Lecurieux-Belfond, Laura

    2014-07-01

    To address environmental and climate issues, alternative technologies to fossil resources are sought after, both for the production of fuels and of chemicals. Algae appear as an attractive solution and have applications in the food, feed, energy or chemistry at large. A study funded by ADEME and conducted by ENEA, a consulting firm for energy and sustainable development for the industrial sector, in partnership with INRIA assessed the potential of algal French resources (micro- and macro-algae) for the production of advanced bio-fuels and molecules of interest (bio-plastic, nutrients etc.) in 2030. This assessment is based both on a model of the French national resources (physical production potential without the use of agricultural land) and what the we now know of the markets concerned and their projection 2030. The analysis shows a physical potential output of up to 9% of the French bio-diesel consumption in 2030 and enough to supply many European markets in algal bio-products. R and d efforts are however required to achieve sufficient technical and economic performance to fully exploit this potential

  7. Investigating potential exogenous tumor initiating and promoting factors for Cutaneous T-Cell Lymphomas (CTCL), a rare skin malignancy

    DEFF Research Database (Denmark)

    Litvinov, Ivan V.; Shtreis, Anna; Kobayashi, Kenneth

    2016-01-01

    -Cell lymphotropic virus type 1 (HTLV1), Epstein-Barr virus (EBV), and herpes simplex virus (HSV). In this report, we review recent evidence evaluating the involvement of these agents in cancer initiation/progression. Most importantly, recent molecular experimental evidence documented for the first time that S....... aureus can activate oncogenic STAT3 signaling in malignant T cells. Specifically, S. aureus Enterotoxin type A (SEA) was recently shown to trigger non-malignant infiltrating T cells to release IL-2 and other cytokines. These signals upon binging to their cognate receptors on malignant T cells...

  8. Clean Energy Policy Analysis: Impact Analysis of Potential Clean Energy Policy Options for the Hawaii Clean Energy Initiative (HCEI)

    Energy Technology Data Exchange (ETDEWEB)

    Busche, S.; Doris, E.; Braccio, R.; Lippert, D.; Finch, P.; O' Toole, D.; Fetter, J.

    2010-04-01

    This report provides detailed analyses of 21 clean energy policy options considered by the Hawaii Clean Energy Initiative working groups for recommendation to the 2010 Hawaii State Legislature. The report considers the impact each policy may have on ratepayers, businesses, and the state in terms of energy saved, clean energy generated, and the financial costs and benefits. The analyses provide insight into the possible impacts, both qualitative and quantitative, that these policies may have in Hawaii based on the experience with these policies elsewhere. As much as possible, the analyses incorporate Hawaii-specific context to reflect the many unique aspects of energy use in the State of Hawaii.

  9. PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

    Science.gov (United States)

    Li, Jiarong; Karaplis, Andrew C.; Huang, Dao C.; Siegel, Peter M.; Camirand, Anne; Yang, Xian Fang; Muller, William J.; Kremer, Richard

    2011-01-01

    Parathyroid hormone–related protein (PTHrP) is a secreted factor expressed in almost all normal fetal and adult tissues. It is involved in a wide range of developmental and physiological processes, including serum calcium regulation. PTHrP is also associated with the progression of skeletal metastases, and its dysregulated expression in advanced cancers causes malignancy-associated hypercalcemia. Although PTHrP is frequently expressed by breast tumors and other solid cancers, its effects on tumor progression are unclear. Here, we demonstrate in mice pleiotropic involvement of PTHrP in key steps of breast cancer — it influences the initiation and progression of primary tumors and metastases. Pthrp ablation in the mammary epithelium of the PyMT-MMTV breast cancer mouse model caused a delay in primary tumor initiation, inhibited tumor progression, and reduced metastasis to distal sites. Mechanistically, it reduced expression of molecular markers of cell proliferation (Ki67) and angiogenesis (factor VIII), antiapoptotic factor Bcl-2, cell-cycle progression regulator cyclin D1, and survival factor AKT1. PTHrP also influenced expression of the adhesion factor CXCR4, and coexpression of PTHrP and CXCR4 was crucial for metastatic spread. Importantly, PTHrP-specific neutralizing antibodies slowed the progression and metastasis of human breast cancer xenografts. Our data identify what we believe to be new functions for PTHrP in several key steps of breast cancer and suggest that PTHrP may constitute a novel target for therapeutic intervention. PMID:22056386

  10. An initial evaluation of potential options for managing riparian reserves of the Aquatic Conservation Strategy of the Northwest Forest Plan

    Science.gov (United States)

    Gordon H. Reeves; Brian R. Pickard; K. Norman. Johnson

    2016-01-01

    The Aquatic Conservation Strategy (ACS) of the Northwest Forest Plan guides management of riparian and aquatic ecosystems on federal lands in western Oregon, western Washington, and northern California. We applied new scientific findings and tools to evaluate two potential options, A and B, for refining interim riparian reserves to meet ACS goals and likely challenges...

  11. Ionic regulation of the plasma membrane potential of rainbow trout (Salmo gairdneri) spermatozoa: Role in the initiation of sperm motility

    International Nuclear Information System (INIS)

    Gatti, J.L.; Billard, R.; Christen, R.

    1990-01-01

    The ionic dependence of the trout sperm plasma membrane potential was analysed by measuring the accumulation of the lipophilic ions 3 H-tetraphenylphosphonium (TPP) and 14 C-thiocyanate (SCN) following dilution in artificial media isotonic to the seminal fluid. Our data showed that the trout sperm plasma membrane has a mixed conductance: the plasma membrane potential is sensitive upon the transmembrane gradients of K+, Na+, and H+. This potential is negative (less than -40 mV) in a 125 mM choline chloride media (ChM) at pH 8.5. Replacement of choline by sodium has a small depolarizing effect. The membrane potential is about -15 mV in a 125 mM potassium chloride and falls near zero mV only if valinomycin is added. In ChM changing the external pH (pHe) greatly affects the membrane potential: its value rises from less than -40 mV at pHe 9.0 to -17 mV at pHe 5.0. This pH effect is observed also in presence of sodium or potassium. A decrease in the transmembrane proton gradient produced by increasing internal pH without changing pHe induces also a depolarisation of the plasma membrane. In the different media in which trout sperm remain immotile after dilution (media with [K+] greater than 20-40 mM or a pH less than 7.5) the plasma membrane is more depolarized than in media allowing motility, suggesting a relationship between the state of membrane polarization and the intracellular effectors of the axonemal movement

  12. Organic food in Denmark – from grass root initiative to market niche: potentials and barriers for further sustainable transition

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard

    2007-01-01

    The mechanisms in the shaping of organic food in Denmark since the 1970’ies are analysed as a contribution to the discussion of strategies for a more sustainable production and consumption of food. The background is the major achievements in Denmark within organic food since the 1970’ies, but also...... the recent years’ reduction in the land converted to organic farming. The analyses are based on experiences from projects, analyses and literature and draw on innovation theory and theory about social construction of technology. The analyses show an ongoing interaction between production, consumption....../use, knowledge and governmental regulation, where these systems constantly are co-shaping each other. The role of the initial conditions in the shaping of the area is shown. The big Danish pork export and the specialised farms have implied a limited focus on organic pig production and more focus on the milk...

  13. Environmental concerns and regulatory initiatives related to hydraulic fracturing in shale gas formations: potential implications for North American gas supply

    Energy Technology Data Exchange (ETDEWEB)

    Sumi, Lisa [Earthworks (Canada)

    2010-09-15

    Shale gas resources have been referred to as a game changer for North America and it is expected that shale gas will account for over 30% of the natural gas production in North America by 2020. However, the development of this resource has raised several concerns, notably in terms of water use and contamination; more stringent regulations could be implemented in the coming years. The aim of this paper is to present the effect that more stringent regulations would have on gas development in the Marcellus shale, which accounts for 20% of North American shale gas production. Information on hydraulic fracturing and its environmental impacts is provided herein, along with information on the regulatory initiatives underway in the Marcellus shale region. This paper pointed out that novel regulations relating to shale gas development could significantly reduce the growth in shale gas production.

  14. Effect of initiation-inhibition and handedness on the patterns of the P50 event-related potential component: a low resolution electromagnetic tomography study

    Directory of Open Access Journals (Sweden)

    Capsalis Christos N

    2009-12-01

    Full Text Available Abstract Background Recent research recognizes the association between handedness, linguistic processes and cerebral networks subserving executive functioning, but the nature of this association remains unclear. Since the P50 event related potential (ERP is considered to reflect thalamocortical processes in association with working memory (WM operation the present study focuses on P50 patterns elicited during the performance of a linguistic related executive functioning test in right- and left-handers. Methods In 64 young adults with a high educational level (33 left-handed the P50 event-related potential was recorded while performing the initiation and inhibition condition of a modified version of the Hayling Sentence Completion test adjusted to induce WM. The manual preference of the participants was evaluated with the use of the Edinburgh Handedness Inventory (EHI. Results P50 showed greater amplitudes in left- than in right-handers, mainly in frontal leads, in the initiation condition. Reduced amplitudes in inhibition compared to initiation condition were observed in left-handers. Low Resolution Electromagnetic Tomography (LORETA analysis showed lower frontal lobe activation in the inhibition than in the initiation condition in both right- and left-handers. Also, LORETA yielded that right-handers exhibited greater activation in the inhibition condition than left-handers. Additionally, LORETA showed assymetrical hemispheric activation patterns in right-handers, in contrast to symmetrical patterns observed in left-handers. Higher P50 amplitudes were recorded in right-hemisphere of right-handers in the initiation condition. Conclusion Brain activation, especially the one closely related to thalamocortical function, elicited during WM operation involving initiation and inhibition processes appears to be related to handedness.

  15. Addressing the Misuse Potential of Life Science Research-Perspectives From a Bottom-Up Initiative in Switzerland.

    Science.gov (United States)

    Oeschger, Franziska M; Jenal, Ursula

    2018-01-01

    Codes of conduct have received wide attention as a bottom-up approach to foster responsibility for dual use aspects of life science research within the scientific community. In Switzerland, a series of discussion sessions led by the Swiss Academy of Sciences with over 40 representatives of most Swiss academic life science research institutions has revealed that while a formal code of conduct was considered too restrictive, a bottom-up approach toward awareness raising and education and demonstrating scientists' responsibility toward society was highly welcomed. Consequently, an informational brochure on "Misuse potential and biosecurity in life sciences research" was developed to provide material for further discussions and education.

  16. A brave new world: considering the pedagogic potential of Virtual World Field Trips (VWFTs in initial teacher education

    Directory of Open Access Journals (Sweden)

    Fitzsimons Sabrina

    2016-07-01

    Full Text Available In its broadest and historical sense, place-based education refers to education that occurs outside of the physical boundaries of a school building (Dewey 1910; Sobel 1996; Theobald 1997; Woodhouse and Knapp 2000. Place-based education, colloquially referred to as the ‘field trip’, is predominantly considered a pedagogic tool of the sciences. It involves a physical movement from the school-based location to a place of interest, for example, a geography field trip to an ecological landscape or science visit to a local museum. This paper considers the use of virtual world field trips (VWFTs within the context of a pre-service Teacher Education programme. The paper presents data from one undergraduate module offered on a programme of initial teacher education. The paper identifies three significant elements of virtual world field trips: place, people and content. First, the virtual world can provide access to places not possible in the offline context as a result of geographic, economic or religious factors. Second, exposure to and dialogue with a variety of world views can challenge students’ assumptions, facilitate reflection and provide an opportunity for oneto-one teaching encounters. Third, from a teacher educator perspective, engagement in virtual world field trips can provide a space for teachers to model teaching methodologies and model creative learning techniques, thus providing student teachers with an insight into different approaches to teaching.

  17. Do transition towns have the potential to promote health and well-being? A health impact assessment of a transition town initiative.

    Science.gov (United States)

    Richardson, J; Nichols, A; Henry, T

    2012-11-01

    Climate change and energy vulnerability present significant challenges for the development and sustainability of our communities. The adverse effects will most likely impact on those already experiencing poverty, as energy and food costs will rise, thus increasing inequalities in health. Transition town initiatives seek to build cohesive sustainable communities to prepare for a future with limited oil and a changing climate. Increasingly, public health practitioners are interested in the role of transition towns as a community development initiative, and their potential to support the wider public health agenda. Health impact assessment (HIA) is an evidence-based process that aims to predict the positive and negative impacts of a strategy, proposal or development. The HIA process provides an opportunity to promote sustainable communities by ensuring that new strategies and developments are considered in the context of their contribution to the health and well-being of local populations. The aim of this study was to use an HIA to examine the potential health and well-being benefits of two related transition town initiatives. A rapid HIA to consider the potential lifestyle changes and health and well-being impacts of Transition Together/Transition Streets (TT/TS) projects. An HIA template was used to assess key documents related to the TT/TS initiatives and those related to the characteristics of the community. Additionally, meetings with 12 key informants (four involved in TT/TS and eight purposively selected for their local knowledge) were held using the HIA template to focus the discussion. The findings highlight the associated lifestyle changes such as increased physical activity and healthy eating, and possible social and well-being benefits of engagement in such an initiative. Engagement may be limited to those already concerned about environmental issues. This paper illustrates the important links between transition towns and the wider public health agenda

  18. Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human Na(V)1.1 mutation.

    Science.gov (United States)

    Hedrich, Ulrike B S; Liautard, Camille; Kirschenbaum, Daniel; Pofahl, Martin; Lavigne, Jennifer; Liu, Yuanyuan; Theiss, Stephan; Slotta, Johannes; Escayg, Andrew; Dihné, Marcel; Beck, Heinz; Mantegazza, Massimo; Lerche, Holger

    2014-11-05

    Mutations in SCN1A and other ion channel genes can cause different epileptic phenotypes, but the precise mechanisms underlying the development of hyperexcitable networks are largely unknown. Here, we present a multisystem analysis of an SCN1A mouse model carrying the NaV1.1-R1648H mutation, which causes febrile seizures and epilepsy in humans. We found a ubiquitous hypoexcitability of interneurons in thalamus, cortex, and hippocampus, without detectable changes in excitatory neurons. Interestingly, somatic Na(+) channels in interneurons and persistent Na(+) currents were not significantly changed. Instead, the key mechanism of interneuron dysfunction was a deficit of action potential initiation at the axon initial segment that was identified by analyzing action potential firing. This deficit increased with the duration of firing periods, suggesting that increased slow inactivation, as recorded for recombinant mutated channels, could play an important role. The deficit in interneuron firing caused reduced action potential-driven inhibition of excitatory neurons as revealed by less frequent spontaneous but not miniature IPSCs. Multiple approaches indicated increased spontaneous thalamocortical and hippocampal network activity in mutant mice, as follows: (1) more synchronous and higher-frequency firing was recorded in primary neuronal cultures plated on multielectrode arrays; (2) thalamocortical slices examined by field potential recordings revealed spontaneous activities and pathological high-frequency oscillations; and (3) multineuron Ca(2+) imaging in hippocampal slices showed increased spontaneous neuronal activity. Thus, an interneuron-specific generalized defect in action potential initiation causes multisystem disinhibition and network hyperexcitability, which can well explain the occurrence of seizures in the studied mouse model and in patients carrying this mutation. Copyright © 2014 the authors 0270-6474/14/3414874-16$15.00/0.

  19. A vertical hydroclimatology of the Upper Indus Basin and initial insights to potential hydrological change in the region

    Science.gov (United States)

    Forsythe, Nathan; Kilsby, Chris G.; Fowler, Hayley J.; Archer, David R.

    2010-05-01

    The water resources of the Upper Indus Basin (UIB) are of the utmost importance to the economic wellbeing of Pakistan. The irrigated agriculture made possible by Indus river runoff underpins the food security for Pakistan's nearly 200 million people. Contributions from hydropower account for more than one fifth of peak installed electrical generating capacity in a country where widespread, prolonged load-shedding handicaps business activity and industrial development. Pakistan's further socio-economic development thus depends largely on optimisation of its precious water resources. Confident, accurate projections of future water resource availability and variability are urgent insights needed by development planners and infrastructure managers at all levels. Correctly projecting future hydrological conditions depends first and foremost on a thorough understanding of the underlying mechanisms and processes of present hydroclimatology. The vertical and horizontal spatial variations in key climate parameters (temperature, precipitation) govern the contributions of the various elevation zones and subcatchments comprising the UIB. Trends in this complex mountainous region are highly varied by season and parameter. Observed changes here often do not match general global trends or even necessarily those found in neighbouring regions. This study considers data from a variety sources in order to compose the most complete picture possible of the vertical hydroclimatology of the UIB. The study presents the observed climatology and trends for precipitation and temperature from local observations at long-record meteorological stations (Pakistan Meteorological Department). These data are compared to characterisations of additional water cycle parameters (humidity, cloud, snow cover and snow-water-equivalent) derived from local short-record automatic weather stations, the ECMWF ‘ERA' reanalysis projects and satellite based observations (AVHRR, MODIS, etc). The potential

  20. SU-C-204-07: Radiation Therapy as a Potential Treatment for Obesity: Initial Data from a Preclinical Investigation

    International Nuclear Information System (INIS)

    Pasciak, A; Bradley, Y; Nodit, L; Bourgeois, A; Paxton, B; Arepally, A

    2016-01-01

    Purpose: To evaluate the feasibility of Yttrium-90 (90Y) radionuclide therapy as a potential treatment for obesity in a porcine model. As the only appetite-stimulating hormone, localized targeting of ghrelin-producing X/A cells in the fundus of the stomach using 90Y may reduce serum ghrelin levels and decrease hunger. Methods: Under approval of the University of Tennessee IACUC, 8 young female pigs aged 12–13 weeks and weighing 21.8–28.1 Kg were included in this study. Six animals underwent transfemoral angiography as part of a two-day procedure involving: (1) infusion of 99mTc-MAA, followed by nuclear scintigraphy and contrast-enhanced CT for treatment-planning and (2) administration of resin 90Y microspheres into the stomach fundus. Calibrated 90Y activities were infused into the main left gastric and the gastric artery arising from the splenic to yield predetermined fundal absorbed doses. Control animals underwent a sham procedure with saline and contrast. Weekly animal weight and serum ghrelin were measured along with post-euthanasia histologic analyses of mucosal integrity and ghrelin immunoreactive cell-density. Results: 90Y radioembolization was administered to six pigs in dosages from 46.3 to 105.1 MBq resulting in average fundal absorbed doses between 35.5 and 91.9 Gy. No animal showed any signs of pain or GI complication through the duration of the study. Ghrelin immunoreactive cell-density was significantly lower in treated vs. control animals in both the stomach fundus (13.5 vs 34.8, P < 0.05) and body (11.2 vs 19.8, P < 0.05). A trend towards decreased weight gain in treated animals as well as a decrease in explanted stomach volume was also noted. Conclusion: The safety and technical feasibility of radiation therapy using 90Y radioembolization as a potential treatment for obesity has been demonstrated at fundal absorbed doses over 90 Gy. Preliminary data is suggestive of short-term safety and potential efficacy, however, further animal studies are

  1. SU-C-204-07: Radiation Therapy as a Potential Treatment for Obesity: Initial Data from a Preclinical Investigation

    Energy Technology Data Exchange (ETDEWEB)

    Pasciak, A; Bradley, Y; Nodit, L; Bourgeois, A; Paxton, B; Arepally, A [University of Tennessee Medical Center, Knoxville, TN (United States)

    2016-06-15

    Purpose: To evaluate the feasibility of Yttrium-90 (90Y) radionuclide therapy as a potential treatment for obesity in a porcine model. As the only appetite-stimulating hormone, localized targeting of ghrelin-producing X/A cells in the fundus of the stomach using 90Y may reduce serum ghrelin levels and decrease hunger. Methods: Under approval of the University of Tennessee IACUC, 8 young female pigs aged 12–13 weeks and weighing 21.8–28.1 Kg were included in this study. Six animals underwent transfemoral angiography as part of a two-day procedure involving: (1) infusion of 99mTc-MAA, followed by nuclear scintigraphy and contrast-enhanced CT for treatment-planning and (2) administration of resin 90Y microspheres into the stomach fundus. Calibrated 90Y activities were infused into the main left gastric and the gastric artery arising from the splenic to yield predetermined fundal absorbed doses. Control animals underwent a sham procedure with saline and contrast. Weekly animal weight and serum ghrelin were measured along with post-euthanasia histologic analyses of mucosal integrity and ghrelin immunoreactive cell-density. Results: 90Y radioembolization was administered to six pigs in dosages from 46.3 to 105.1 MBq resulting in average fundal absorbed doses between 35.5 and 91.9 Gy. No animal showed any signs of pain or GI complication through the duration of the study. Ghrelin immunoreactive cell-density was significantly lower in treated vs. control animals in both the stomach fundus (13.5 vs 34.8, P < 0.05) and body (11.2 vs 19.8, P < 0.05). A trend towards decreased weight gain in treated animals as well as a decrease in explanted stomach volume was also noted. Conclusion: The safety and technical feasibility of radiation therapy using 90Y radioembolization as a potential treatment for obesity has been demonstrated at fundal absorbed doses over 90 Gy. Preliminary data is suggestive of short-term safety and potential efficacy, however, further animal studies are

  2. The OH-initiated atmospheric oxidation of cyclopentene: A coupled-cluster study of the potential energy surface

    Science.gov (United States)

    Zhang, Weichao; Du, Benni

    2013-07-01

    We performed the first theoretical potential energy surface investigation on the mechanism and products of the reaction of OH+ cyclopentene in the absence and presence of O2 by using high-level quantum chemical methods CCSD(T)/6-311++G(d,p)//BH&HLYP/6-311++G(d,p)+ZPE × 0.9335. Energies for several species are also refined at the CCSD(T)/cc-pVTZ levels of theory. The calculations indicate that the major products are cyclopentanone, 1-cyclopenten-1-ol, and 2-cyclopenten-1-ol in the absence of O2, which are in qualitative accordance with the available experimental observations. In the presence of O2, the dominant products are predicted to be glutaraldehyde and 1,2-epoxycyclopentanol.

  3. Different role of TTX-sensitive voltage-gated sodium channel (NaV 1) subtypes in action potential initiation and conduction in vagal airway nociceptors.

    Science.gov (United States)

    Kollarik, M; Sun, H; Herbstsomer, R A; Ru, F; Kocmalova, M; Meeker, S N; Undem, B J

    2018-04-15

    The action potential initiation in the nerve terminals and its subsequent conduction along the axons of afferent nerves are not necessarily dependent on the same voltage-gated sodium channel (Na V 1) subunits. The action potential initiation in jugular C-fibres within airway tissues is not blocked by TTX; nonetheless, conduction of action potentials along the vagal axons of these nerves is often dependent on TTX-sensitive channels. This is not the case for nodose airway Aδ-fibres and C-fibres, where both action potential initiation and conduction is abolished by TTX or selective Na V 1.7 blockers. The difference between the initiation of action potentials within the airways vs. conduction along the axons should be considered when developing Na V 1 blocking drugs for topical application to the respiratory tract. The action potential (AP) initiation in the nerve terminals and its subsequent AP conduction along the axons do not necessarily depend on the same subtypes of voltage-gated sodium channels (Na V 1s). We evaluated the role of TTX-sensitive and TTX-resistant Na V 1s in vagal afferent nociceptor nerves derived from jugular and nodose ganglia innervating the respiratory system. Single cell RT-PCR was performed on vagal afferent neurons retrogradely labelled from the guinea pig trachea. Almost all of the jugular neurons expressed the TTX-sensitive channel Na V 1.7 along with TTX-resistant Na V 1.8 and Na V 1.9. Tracheal nodose neurons also expressed Na V 1.7 but, less frequently, Na V 1.8 and Na V 1.9. Na V 1.6 were expressed in ∼40% of the jugular and 25% of nodose tracheal neurons. Other Na V 1 α subunits were only rarely expressed. Single fibre recordings were made from the vagal nodose and jugular nerve fibres innervating the trachea or lung in the isolated perfused vagally-innervated preparations that allowed for selective drug delivery to the nerve terminal compartment (AP initiation) or to the desheathed vagus nerve (AP conduction). AP initiation in

  4. Communication: Estimating the initial biasing potential for λ-local-elevation umbrella-sampling (λ-LEUS) simulations via slow growth

    International Nuclear Information System (INIS)

    Bieler, Noah S.; Hünenberger, Philippe H.

    2014-01-01

    In a recent article [Bieler et al., J. Chem. Theory Comput. 10, 3006–3022 (2014)], we introduced a combination of the λ-dynamics (λD) approach for calculating alchemical free-energy differences and of the local-elevation umbrella-sampling (LEUS) memory-based biasing method to enhance the sampling along the alchemical coordinate. The combined scheme, referred to as λ-LEUS, was applied to the perturbation of hydroquinone to benzene in water as a test system, and found to represent an improvement over thermodynamic integration (TI) in terms of sampling efficiency at equivalent accuracy. However, the preoptimization of the biasing potential required in the λ-LEUS method requires “filling up” all the basins in the potential of mean force. This introduces a non-productive pre-sampling time that is system-dependent, and generally exceeds the corresponding equilibration time in a TI calculation. In this letter, a remedy is proposed to this problem, termed the slow growth memory guessing (SGMG) approach. Instead of initializing the biasing potential to zero at the start of the preoptimization, an approximate potential of mean force is estimated from a short slow growth calculation, and its negative used to construct the initial memory. Considering the same test system as in the preceding article, it is shown that of the application of SGMG in λ-LEUS permits to reduce the preoptimization time by about a factor of four

  5. Communication: Estimating the initial biasing potential for λ-local-elevation umbrella-sampling (λ-LEUS) simulations via slow growth

    Energy Technology Data Exchange (ETDEWEB)

    Bieler, Noah S.; Hünenberger, Philippe H., E-mail: phil@igc.phys.chem.ethz.ch [Laboratory of Physical Chemistry, ETH Zürich, CH-8093 Zürich (Switzerland)

    2014-11-28

    In a recent article [Bieler et al., J. Chem. Theory Comput. 10, 3006–3022 (2014)], we introduced a combination of the λ-dynamics (λD) approach for calculating alchemical free-energy differences and of the local-elevation umbrella-sampling (LEUS) memory-based biasing method to enhance the sampling along the alchemical coordinate. The combined scheme, referred to as λ-LEUS, was applied to the perturbation of hydroquinone to benzene in water as a test system, and found to represent an improvement over thermodynamic integration (TI) in terms of sampling efficiency at equivalent accuracy. However, the preoptimization of the biasing potential required in the λ-LEUS method requires “filling up” all the basins in the potential of mean force. This introduces a non-productive pre-sampling time that is system-dependent, and generally exceeds the corresponding equilibration time in a TI calculation. In this letter, a remedy is proposed to this problem, termed the slow growth memory guessing (SGMG) approach. Instead of initializing the biasing potential to zero at the start of the preoptimization, an approximate potential of mean force is estimated from a short slow growth calculation, and its negative used to construct the initial memory. Considering the same test system as in the preceding article, it is shown that of the application of SGMG in λ-LEUS permits to reduce the preoptimization time by about a factor of four.

  6. Is the rotation of the femural head a potential initiation for cutting out? A theoretical and experimental approach

    LENUS (Irish Health Repository)

    Lenich, Andreas

    2011-04-22

    Abstract Background Since cut-out still remains one of the major clinical challenges in the field of osteoporotic proximal femur fractures, remarkable developments have been made in improving treatment concepts. However, the mechanics of these complications have not been fully understood. We hypothesize using the experimental data and a theoretical model that a previous rotation of the femoral head due to de-central implant positioning can initiate a cut-out. Methods In this investigation we analysed our experimental data using two common screws (DHS\\/Gamma 3) and helical blades (PFN A\\/TFN) for the fixation of femur fractures in a simple theoretical model applying typical gait pattern on de-central positioned implants. In previous tests during a forced implant rotation by a biomechanical testing machine in a human femoral head the two screws showed failure symptoms (2-6Nm) at the same magnitude as torques acting in the hip during daily activities with de-central implant positioning, while the helical blades showed a better stability (10-20Nm). To calculate the torque of the head around the implant only the force and the leverarm is needed (N [Nm] = F [N] * × [m]). The force F is a product of the mass M [kg] multiplied by the acceleration g [m\\/s2]. The leverarm is the distance between the center of the head of femur and the implant center on a horizontal line. Results Using 50% of 75 kg body weight a torque of 0.37Nm for the 1 mm decentralized position and 1.1Nm for the 3 mm decentralized position of the implant was calculated. At 250% BW, appropriate to a normal step, torques of 1.8Nm (1 mm) and 5.5Nm (3 mm) have been calculated. Comparing of the experimental and theoretical results shows that both screws fail in the same magnitude as torques occur in a more than 3 mm de-central positioned implant. Conclusion We conclude the center-center position in the head of femur of any kind of lag screw or blade is to be achieved to minimize rotation of the femoral head

  7. Is the rotation of the femoral head a potential initiation for cutting out? A theoretical and experimental approach.

    Science.gov (United States)

    Lenich, Andreas; Bachmeier, Samuel; Prantl, Lukas; Nerlich, Michael; Hammer, Jochen; Mayr, Edgar; Al-Munajjed, Amir Andreas; Füchtmeier, Bernd

    2011-04-22

    Since cut-out still remains one of the major clinical challenges in the field of osteoporotic proximal femur fractures, remarkable developments have been made in improving treatment concepts. However, the mechanics of these complications have not been fully understood.We hypothesize using the experimental data and a theoretical model that a previous rotation of the femoral head due to de-central implant positioning can initiate a cut-out. In this investigation we analysed our experimental data using two common screws (DHS/Gamma 3) and helical blades (PFN A/TFN) for the fixation of femur fractures in a simple theoretical model applying typical gait pattern on de-central positioned implants. In previous tests during a forced implant rotation by a biomechanical testing machine in a human femoral head the two screws showed failure symptoms (2-6Nm) at the same magnitude as torques acting in the hip during daily activities with de-central implant positioning, while the helical blades showed a better stability (10-20Nm).To calculate the torque of the head around the implant only the force and the leverarm is needed (N [Nm] = F [N] * × [m]). The force F is a product of the mass M [kg] multiplied by the acceleration g [m/s2]. The leverarm is the distance between the center of the head of femur and the implant center on a horizontal line. Using 50% of 75 kg body weight a torque of 0.37Nm for the 1 mm decentralized position and 1.1Nm for the 3 mm decentralized position of the implant was calculated. At 250% BW, appropriate to a normal step, torques of 1.8Nm (1 mm) and 5.5Nm (3 mm) have been calculated.Comparing of the experimental and theoretical results shows that both screws fail in the same magnitude as torques occur in a more than 3 mm de-central positioned implant. We conclude the center-center position in the head of femur of any kind of lag screw or blade is to be achieved to minimize rotation of the femoral head and to prevent further mechanical complications.

  8. Identification and Initial Characterization of the Effectors of an Anther Smut Fungus and Potential Host Target Proteins

    Directory of Open Access Journals (Sweden)

    Venkata S. Kuppireddy

    2017-11-01

    Full Text Available (1 Background: Plant pathogenic fungi often display high levels of host specificity and biotrophic fungi; in particular, they must manipulate their hosts to avoid detection and to complete their obligate pathogenic lifecycles. One important strategy of such fungi is the secretion of small proteins that serve as effectors in this process. Microbotryum violaceum is a species complex whose members infect members of the Caryophyllaceae; M. lychnidis-dioicae, a parasite on Silene latifolia, is one of the best studied interactions. We are interested in identifying and characterizing effectors of the fungus and possible corresponding host targets; (2 Methods: In silico analysis of the M. lychnidis-dioicae genome and transcriptomes allowed us to predict a pool of small secreted proteins (SSPs with the hallmarks of effectors, including a lack of conserved protein family (PFAM domains and also localized regions of disorder. Putative SSPs were tested for secretion using a yeast secretion trap method. We then used yeast two-hybrid analyses for candidate-secreted effectors to probe a cDNA library from a range of growth conditions of the fungus, including infected plants; (3 Results: Roughly 50 SSPs were identified by in silico analysis. Of these, 4 were studied further and shown to be secreted, as well as examined for potential host interactors. One of the putative effectors, MVLG_01732, was found to interact with Arabidopsis thaliana calcium-dependent lipid binding protein (AtCLB and with cellulose synthase interactive protein 1 orthologues; and (4 Conclusions: The identification of a pool of putative effectors provides a resource for functional characterization of fungal proteins that mediate the delicate interaction between pathogen and host. The candidate targets of effectors, e.g., AtCLB, involved in pollen germination suggest tantalizing insights that could drive future studies.

  9. An initial examination of the potential role of T-cell immunity in protection against feline immunodeficiency virus (FIV) infection.

    Science.gov (United States)

    Aranyos, Alek M; Roff, Shannon R; Pu, Ruiyu; Owen, Jennifer L; Coleman, James K; Yamamoto, Janet K

    2016-03-14

    The importance of vaccine-induced T-cell immunity in conferring protection with prototype and commercial FIV vaccines is still unclear. Current studies performed adoptive transfer of T cells from prototype FIV-vaccinated cats to partial-to-complete feline leukocyte antigen (FLA)-matched cats a day before either homologous FIVPet or heterologous-subtype pathogenic FIVFC1 challenge. Adoptive-transfer (A-T) conferred a protection rate of 87% (13 of 15, p 13 × 10(6) cells were required for A-T protection against FIVFC1 strain, reported to be a highly pathogenic virus resistant to vaccine-induced neutralizing-antibodies. The addition of FLA-matched B cells alone was not protective. The poor quality of the anti-FIV T-cell immunity induced by the vaccine likely contributed to the lack of protection in an FLA-matched recipient against FIVFC1. The quality of the immune response was determined by the presence of high mRNA levels of cytolysin (perforin) and cytotoxins (granzymes A, B, and H) and T helper-1 cytokines (interferon-γ [IFNγ] and IL2). Increased cytokine, cytolysin and cytotoxin production was detected in the donors which conferred protection in A-T studies. In addition, the CD4(+) and CD8(+) T-cell proliferation and/or IFNγ responses to FIV p24 and reverse transcriptase increased with each year in cats receiving 1X-3X vaccine boosts over 4 years. These studies demonstrate that anti-FIV T-cell immunity induced by vaccination with a dual-subtype FIV vaccine is essential for prophylactic protection against AIDS lentiviruses such as FIV and potentially HIV-1. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Effect of enamel organic matrix on the potential of Galla chinensis to promote the remineralization of initial enamel carious lesions in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Linglin; Zou Ling; Li Jiyao; Hao Yuqing; Xiao Liying; Zhou Xuedong; Li Wei, E-mail: leewei2000@sina.co, E-mail: zhll_sc@yahoo.c [State Key Laboratory of Oral Diseases, West China College of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu (China)

    2009-06-15

    Galla chinensis, a natural traditional Chinese medicine with main composition of tannic acid and gallic acid, is formed when the Chinese sumac aphid Baker (Melaphis chinensis bell) parasitizes the levels of Rhus chinensis Mill. Galla chinensis has shown the potential to enhance the remineralization of initial enamel carious lesion, but the mechanism is still unknown. This study was to investigate whether the enamel organic matrix plays a significant role in the potential of Galla chinensis to promote the remineralization of initial enamel caries. Bovine sound enamel blocks and non-organic enamel blocks were demineralized and exposed to a 12 day pH cycling. During the pH cycling, 30 specimens with the enamel organic matrix were randomly divided into three groups, and treated with 1 g L{sup -1} NaF (group A), 4 g L{sup -1} Galla chinensis extract (group B1) or double deionized water (group C1). Twenty specimens without the enamel organic matrix were randomly divided into two groups, and treated with 4 g L{sup -1} Galla chinensis extract (group B2) or double deionized water (group C2). The integrated mineral loss and lesion depth of all the specimens were analysed by transverse microradiography. The integrated mineral loss and lesion depth of group B1 were less than those of groups B2, C1 and C2, and there were no statistical differences among groups B2, C1 and C2. In conclusion, Galla chinensis can enhance the remineralization of initial enamel carious lesion, and the enamel organic matrix plays a significant role in this potential of Galla chinensis.

  11. ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

    Science.gov (United States)

    Goossens, Steven; Radaelli, Enrico; Blanchet, Odile; Durinck, Kaat; Van der Meulen, Joni; Peirs, Sofie; Taghon, Tom; Tremblay, Cedric S.; Costa, Magdaline; Ghahremani, Morvarid Farhang; De Medts, Jelle; Bartunkova, Sonia; Haigh, Katharina; Schwab, Claire; Farla, Natalie; Pieters, Tim; Matthijssens, Filip; Van Roy, Nadine; Best, J. Adam; Deswarte, Kim; Bogaert, Pieter; Carmichael, Catherine; Rickard, Adam; Suryani, Santi; Bracken, Lauryn S.; Alserihi, Raed; Canté-Barrett, Kirsten; Haenebalcke, Lieven; Clappier, Emmanuelle; Rondou, Pieter; Slowicka, Karolina; Huylebroeck, Danny; Goldrath, Ananda W.; Janzen, Viktor; McCormack, Matthew P.; Lock, Richard B.; Curtis, David J.; Harrison, Christine; Berx, Geert; Speleman, Frank; Meijerink, Jules P. P.; Soulier, Jean; Van Vlierberghe, Pieter; Haigh, Jody J.

    2015-01-01

    Early T-cell precursor leukaemia (ETP-ALL) is a high-risk subtype of human leukaemia that is poorly understood at the molecular level. Here we report translocations targeting the zinc finger E-box-binding transcription factor ZEB2 as a recurrent genetic lesion in immature/ETP-ALL. Using a conditional gain-of-function mouse model, we demonstrate that sustained Zeb2 expression initiates T-cell leukaemia. Moreover, Zeb2-driven mouse leukaemia exhibit some features of the human immature/ETP-ALL gene expression signature, as well as an enhanced leukaemia-initiation potential and activated Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signalling through transcriptional activation of IL7R. This study reveals ZEB2 as an oncogene in the biology of immature/ETP-ALL and paves the way towards pre-clinical studies of novel compounds for the treatment of this aggressive subtype of human T-ALL using our Zeb2-driven mouse model. PMID:25565005

  12. Transformation assay in Bhas 42 cells: a model using initiated cells to study mechanisms of carcinogenesis and predict carcinogenic potential of chemicals.

    Science.gov (United States)

    Sasaki, Kiyoshi; Umeda, Makoto; Sakai, Ayako; Yamazaki, Shojiro; Tanaka, Noriho

    2015-01-01

    Transformation assays using cultured cells have been applied to the study of carcinogenesis. Although various cell systems exist, few cell types such as BALB/c 3T3 subclones and Syrian hamster embryo cells have been used to study chemically induced two-stage carcinogenesis. Bhas 42 cells were established as a clone by the transfection with the v-Ha-ras gene into mouse BALB/c 3T3 A31-1-1 cells and their subsequent selection based on their sensitivity to 12-O-tetradecanoylphorbol-13-acetate. Using Bhas 42 cells, transformed foci were induced by the treatment with nongenotoxic carcinogens, most of which act as tumor promoters. Therefore, Bhas 42 cells were considered to be a model of initiated cells. Subsequently, not only nongenotoxic carcinogens but also genotoxic carcinogens, most of which act as tumor initiators, were found to induce transformed foci by the modification of the protocol. Furthermore, transformation of Bhas 42 cells was induced by the transfection with genes of oncogenic potential. We interpret this high sensitivity of Bhas 42 cells to various types of carcinogenic stimuli to be related to the multistage model of carcinogenesis, as the transfection of v-Ha-ras gene further advances the parental BALB/c 3T3 A31-1-1 cells toward higher transforming potential. Thus, we propose that Bhas 42 cells are a novel and sensitive cell line for the analysis of carcinogenesis and can be used for the detection of not only carcinogenic substances but also gene alterations related to oncogenesis. This review will address characteristics of Bhas 42 cells, the transformation assay protocol, validation studies, and the various chemicals tested in this assay.

  13. A Decision Support System (DSS for Project Management in the Bio-diesel Industry

    Directory of Open Access Journals (Sweden)

    Alin Paul OLTEANU

    2011-01-01

    Full Text Available The European biodiesel industry is currently facing several challenges affecting the profitability of investment projects in the industry. Among these challenges are higher prices for oilseeds, which are the main input for biodiesel production, lower fiscal support by national governments for biodiesel producers and high price volatility of oil markets. Thus identifying all opportunities for optimizing the value chain and lower the production cost of biodiesel is a main requirement for an efficient project management in the biodiesel industry. The paper addresses this topic by developing a decision support system tailored to the needs of Romanian investors in biodiesel production. The system optimizes the main activities of the biodiesel value chain and supports the decision making process at management level. In addition the DSS enables the user to perform sensitivity analysis based on varying various input parameter.

  14. Differences in rheological profile of regular diesel and bio-diesel fuel

    Directory of Open Access Journals (Sweden)

    Jiří Čupera

    2010-01-01

    Full Text Available Biodiesel represents a promising alternative to regular fossil diesel. Fuel viscosity markedly influences injection, spraying and combustion, viscosity is thus critical factor to be evaluated and monitored. This work is focused on quantifying the differences in temperature dependent kinematic viscosity regular diesel fuel and B30 biodiesel fuel. The samples were assumed to be Newtonian fluids. Vis­co­si­ty was measured on a digital rotary viscometer in a range of 0 to 80 °C. More significant difference between minimum and maximum values was found in case of diesel fuel in comparison with biodiesel fuel. Temperature dependence of both fuels was modeled using several mathematical models – polynomial, power and Gaussian equation. The Gaussian fit offers the best match between experimental and computed data. Description of viscosity behavior of fuels is critically important, e.g. when considering or calculating running efficiency and performance of combustion engines. The models proposed in this work may be used as a tool for precise prediction of rheological behavior of diesel-type fuels.

  15. Developing New Alternative Energy in Virginia: Bio-Diesel from Algae

    Energy Technology Data Exchange (ETDEWEB)

    Hatcher, Patrick [Old Dominion University

    2012-03-29

    The overall objective of this study was to select chemical processing equipment, install and operate that equipment to directly convert algae to biodiesel via a reaction patented by Old Dominion University (Pat. No. US 8,080,679B2). This reaction is a high temperature (250- 330{degrees}C) methylation reaction utilizing tetramethylammonium hydroxide (TMAH) to produce biodiesel. As originally envisioned, algal biomass could be treated with TMAH in methanol without the need to separately extract triacylglycerides (TAG). The reactor temperature allows volatilization and condensation of the methyl esters whereas the spent algae solids can be utilized as a high-value fertilizer because they are minimally charred. During the course of this work and immediately prior to commencing, we discovered that glycerol, a major by-product of the conventional transesterification reaction for biofuels, is not formed but rather three methoxylated glycerol derivatives are produced. These derivatives are high-value specialty green chemicals that strongly upgrade the economics of the process, rendering this approach as one that now values the biofuel only as a by-product, the main value products being the methoxylated glycerols. A horizontal agitated thin-film evaporator (one square foot heat transfer area) proved effective as the primary reactor facilitating the reaction and vaporization of the products, and subsequent discharge of the spent algae solids that are suitable for supplementing petrochemicalbased fertilizers for agriculture. Because of the size chosen for the reactor, we encountered problems with delivery of the algal feed to the reaction zone, but envision that this problem could easily disappear upon scale-up or can be replaced economically by incorporating an extraction process. The objective for production of biodiesel from algae in quantities that could be tested could not be met, but we implemented use of soybean oil as a surrogate TAG feed to overcome this limitation. The positive economics of this process are influenced by the following: 1. the weight percent of dry algae in suspension that can be fed into the evaporator, 2. the alga species’ ability to produce a higher yield of biodiesel, 3. the isolation of valuable methoxylated by-products, 4. recycling and regeneration of methanol and TMAH, and 5. the market value of biodiesel, commercial agricultural fertilizer, and the three methoxylated by-products. The negative economics of the process are the following: 1. the cost of producing dried, ground algae, 2. the capital cost of the equipment required for feedstock mixing, reaction, separation and recovery of products, and reactant recycling, and 3. the electrical cost and other utilities. In this report, the economic factors and results are assembled to predict the commercialization cost and its viability. This direct conversion process and equipment discussed herein can be adapted for various feedstocks including: other algal species, vegetable oil, jatropha oil, peanut oil, sunflower oil, and other TAG containing raw materials as a renewable energy resource.

  16. Chemical structures and thermal properties of polyesters obtained from different samples of bio diesel epoxidized

    International Nuclear Information System (INIS)

    Samios, Dimitrios; Reiznautt, Quelen B.; Nicolau, Aline; Martini, Denise D.; Chagas, Arthur L. das

    2009-01-01

    In this work new structures from oligo esters and polyesters from different oils (olive oil, sunflower oil and linseed oil) were synthesized and characterized. Oligo esters and polyesters were synthesized from the reaction of fatty acid methyl epoxy-esters, obtained from different oils, with cis-1,2-cyclohexanedicarboxylic anhydride in the presence of triethylamine (TEA). Different amounts of the resin 1,4-butanediol diglycidyl ether (BDGE) were added in order to increase the capacity of crosslinking. The molar ratio of BDGE used in system was between 0 and 0.066. The intermediate structures, as well as the oligo esters and polyesters produced, were analyzed by using Fourier Transform Infrared Spectroscopy and Nuclear Magnetic Resonance ( 1 H - NMR). The thermal behavior of the products was realized through differential scanning calorimetry and Thermogravimetric analyses. The presence of BDGE in the materials chains increases the bonding capacity resulting in a higher molecular weight material which presents good thermal stability. (author)

  17. Temperature and driving cycle influence SVOC emissions from (bio-) diesel trucks

    Data.gov (United States)

    U.S. Environmental Protection Agency — The present study examines the effects of fuel (an ultra-low sulfur diesel [ULSD] versus a 20% v/v soy-based biodiesel—80% v/v petroleum blend [B20]), temperature,...

  18. Productions of palm oil bio diesel whit heterogeneous basic catalysts compared to conventional homogeneous catalysts

    International Nuclear Information System (INIS)

    Rios, Luis A; Franco C, Alexander; Zuleta S, Ernesto

    2009-01-01

    The conventional process to produce biodiesel involves the presence of homogeneous basic catalysts. However, these catalysts have disadvantages associated to the need of purification steps, which increase the cost of the final product and generate pollution problems caused by the effluents. This paper compares different homogeneous and heterogeneous catalysts for the biodiesel production from palm oil. For this, heterogeneous catalysts supported on alumina were prepared and characterized by nitrogen adsorption, scanning electron microscopy, energy dispersive X ray spectroscopy and X ray diffraction. Transesterification of palm oil with methanol was accomplished at 60 celsius degrade and one hour, varying methanol/oil ratio, the type of catalyst and its concentration. Yields of the reaction and purity of the so obtained biodiesel were evaluated. Comparing the catalysts performance, based on the amount, was found that sodium methoxide (CH 3 ONa) and potassium carbonate supported on alumina (K 2 CO 3 /Al 2 O 3 ) were the catalysts that give the higher purity of biodiesel (96.8 and 95.85% respectively). When was determined the active site quality, by dividing the performance by each mole of active sites, it was found that calcined Na 2 SO 4 /Al 2 O 3 has the most active sites.

  19. Bio-Diesel Production from Oil of Orange ( Citrus Sinensis ) Peels as ...

    African Journals Online (AJOL)

    Although, in Nigeria orange peels are considered as a waste, this study is intended to convert the waste into wealth by establishing the production of biodiesel with oil obtained from orange peels; using transeterification process. Oil from sun-dried/ ground orange peels were extractedusing n-hexane. Transesterification ...

  20. EXPERIMENTAL RESEARCHES OF THERMO-PHYSICAL AND PHYSICOCHEMICAL INTERNALS OF BIO-DIESEL FUEL

    OpenAIRE

    V. N. Goryachkin; A. V. Ivaschenko

    2010-01-01

    The conducted researches are related to transfer of diesel engines to biodiesel fuel. The technique and results of an experimental research of thermo-physical and physical-and-chemical properties of biodiesel fuel as well as mixes of biodiesel fuel with the petroleum one are presented.

  1. EXPERIMENTAL RESEARCHES OF THERMO-PHYSICAL AND PHYSICOCHEMICAL INTERNALS OF BIO-DIESEL FUEL

    Directory of Open Access Journals (Sweden)

    V. N. Goryachkin

    2010-11-01

    Full Text Available The conducted researches are related to transfer of diesel engines to biodiesel fuel. The technique and results of an experimental research of thermo-physical and physical-and-chemical properties of biodiesel fuel as well as mixes of biodiesel fuel with the petroleum one are presented.

  2. Potential of Biomass for Energy. Market Survey Portugal

    International Nuclear Information System (INIS)

    2007-03-01

    The objective of this market survey is to provide information about the biomass sector in Portugal, relevant to mainly small and medium-sized enterprises (SME) in the Netherlands that are interested to strengthen their position in that sector. Much knowledge could be gathered from conversations with the partners of Sunergy, the company responsible for this survey. Sunergy is producing bio-diesel, and considering further investments in the solid biomass sector, and therefore well familiar with the developments. Other interviews were held with representatives of the Government (DGGE), association of forestry owners (AFLOPS), a biomass trading SME (Sobioen), the leading environmental NGO (Quercus), and an association representing the paper- and pulp industry (CELPA). Chapter 1 is a general introduction on biomass. Chapter 2 gives the background of the Portuguese energy sector and the relative importance of renewable and biomass energies within this market. Some prospects for future developments of the different renewable sources are given. Portugal's energy sector is dominated by a small number of players, which are introduced. Also the current policies and incentives (subsidies) are presented. In Chapter 3 the focus is on the Portuguese biomass sector, presenting the current use of biomass in each of the subsectors: transport, electricity and heat, and an overview of the policy framework specifically for biomass. Chapter 4 is a literature review of the market for existing and potential biomass resources, including demand, supply and other characteristics. Chapter 5 synthesizes the previous chapters. Also an overview of key drivers and key constraints for growth of this sector is given, leading to conclusions regarding the opportunities for Dutch companies. Finally, further information on how to proceed once the interest for Portugal's biomass sector is vested is listed at the end of Chapter 5

  3. Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additive

    Directory of Open Access Journals (Sweden)

    Whittingham Andrew

    2007-12-01

    Full Text Available Abstract Nanotechnology is the new industrial revolution of the 21st Century as the various processes lead to radical improvements in medicine, manufacturing, energy production, land remediation, information technology and many other everyday products and applications. With this revolution however, there are undoubted concerns for health, safety and the environment which arise from the unique nature of materials and processes at the nanometre scale. The in vitro assays used in the screening strategy are all validated, internationally accepted protocols and provide a useful indication of potential toxicity of a chemical as a result of effects on various toxicological endpoints such as local site of contact (dermal irritation, general cytotoxicity and mutagenicity. The initial in vitro screening strategy described in this paper to investigate the potential health implications, if any, which may arise following exposure to one specific application of nanoparticulate cerium oxide used as a diesel fuel borne catalyst, reflects a precautionary approach and the results will inform judgement on how best to proceed to ensure safe use.

  4. Combustion characteristics of the mustard methyl esters

    International Nuclear Information System (INIS)

    Bannikov, M.G.; Vasilev, I.P.

    2011-01-01

    Mustard Methyl Esters (further bio diesel) and regular diesel fuel were tested in direct injection diesel engine. Analysis of experimental data was supported by an analysis of fuel injection and combustion characteristics. Engine fuelled with bio diesel had increased brake specific fuel consumption, reduced nitrogen oxides emission and smoke opacity, moderate increase in carbon monoxide emission with essentially unchanged unburned hydrocarbons emission. Increase in fuel consumption was attributed to lesser heating value of bio diesel and partially to decreased fuel conversion efficiency. Analysis of combustion characteristics revealed earlier start of injection and shorter ignition delay period of bio diesel. Resulting decrease in maximum rate of heat release and cylinder pressure was the most probable reason for reduced emission of nitrogen oxides. Analysis of combustion characteristics also showed that cetane index determined by ASTM Method D976 is not a proper measure of ignition quality of bio diesel. Conclusion was made on applicability of mustard oil as a source for commercial production of bio diesel in Pakistan. Potentialities of on improving combustion and emissions characteristics of diesel engine by reformulating bio diesel were discussed. (author)

  5. Synthesis, Characterization, and Initial Biological Evaluation of [99m Tc]Tc-Tricarbonyl-labeled DPA-α-MSH Peptide Derivatives for Potential Melanoma Imaging.

    Science.gov (United States)

    Gao, Feng; Sihver, Wiebke; Bergmann, Ralf; Belter, Birgit; Bolzati, Cristina; Salvarese, Nicola; Steinbach, Jörg; Pietzsch, Jens; Pietzsch, Hans-Jürgen

    2018-06-06

    α-Melanocyte stimulating hormone (α-MSH) derivatives target the melanocortin-1 receptor (MC1R) specifically and selectively. In this study, the α-MSH-derived peptide NAP-NS1 (Nle-Asp-His-d-Phe-Arg-Trp-Gly-NH 2 ) with and without linkers was conjugated with 5-(bis(pyridin-2-ylmethyl)amino)pentanoic acid (DPA-COOH) and labeled with [ 99m Tc]Tc-tricarbonyl by two methods. With the one-pot method the labeling was faster than with the two-pot method, while obtaining similarly high yields. Negligible trans-chelation and high stability in physiological solutions was determined for the [ 99m Tc]Tc-tricarbonyl-peptide conjugates. Coupling an ethylene glycol (EG)-based linker increased the hydrophilicity. The peptide derivatives displayed high binding affinity in murine B16F10 melanoma cells as well as in human MeWo and TXM13 melanoma cell homogenates. Preliminary in vivo studies with one of the [ 99m Tc]Tc-tricarbonyl-peptide conjugates showed good stability in blood and both renal and hepatobiliary excretion. Biodistribution was performed on healthy rats to gain initial insight into the potential relevance of the 99m Tc-labeled peptides for in vivo imaging. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Poly(allyl methacrylate) functionalized hydroxyapatite nanocrystals via the combination of surface-initiated RAFT polymerization and thiol-ene protocol: a potential anticancer drug nanocarrier.

    Science.gov (United States)

    Bach, Long Giang; Islam, Md Rafiqul; Vo, Thanh-Sang; Kim, Se-Kwon; Lim, Kwon Taek

    2013-03-15

    Hydroxyapatite nanocrystals (HAP NCs) were encapsulated by poly(allyl methacrylate) (PolyAMA) employing controlled surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization of allyl methacrylate to afford HAP-PolyAMA nanohybrids. The subsequent thiol-ene coupling of nanohybrids with 2-mercaptosuccinic acid resulted HAP-Poly(AMA-COOH) possessing multicarboxyl group. The formation of the nanohybrids was confirmed by FT-IR and EDS analyses. The TGA and FE-SEM investigation were further suggested the grafting of PolyAMA onto HAP NCs. The utility of the HAP-PolyAMA nanohybrid as drug carrier was also explored. The pendant carboxyl groups on the external layers of nanohybrids were conjugated with anticancer drug cisplatin to afford HAP-Poly(AMA-COOH)/Pt complex. The formation of the complex was confirmed by FT-IR, XPS, and FE-SEM. In vitro evaluation of the synthesized complex as nanomedicine revealed its potential chemotherapeutic efficacy against cancer cell lines. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. In Vivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors

    Directory of Open Access Journals (Sweden)

    Nabendu Pore

    2015-06-01

    Full Text Available Reprogramming of energy metabolism is one of the emerging hallmarks of cancer. Up-regulation of energy metabolism pathways fuels cell growth and division, a key characteristic of neoplastic disease, and can lead to dependency on specific metabolic pathways. Thus, targeting energy metabolism pathways might offer the opportunity for novel therapeutics. Here, we describe the application of a novel in vivo screening approach for the identification of genes involved in cancer metabolism using a patient-derived pancreatic xenograft model. Lentiviruses expressing short hairpin RNAs (shRNAs targeting 12 different cell surface protein transporters were separately transduced into the primary pancreatic tumor cells. Transduced cells were pooled and implanted into mice. Tumors were harvested at different times, and the frequency of each shRNA was determined as a measure of which ones prevented tumor growth. Several targets including carbonic anhydrase IX (CAIX, monocarboxylate transporter 4, and anionic amino acid transporter light chain, xc- system (xCT were identified in these studies and shown to be required for tumor initiation and growth. Interestingly, CAIX was overexpressed in the tumor initiating cell population. CAIX expression alone correlated with a highly tumorigenic subpopulation of cells. Furthermore, CAIX expression was essential for tumor initiation because shRNA knockdown eliminated the ability of cells to grow in vivo. To the best of our knowledge, this is the first parallel in vivo assessment of multiple novel oncology target genes using a patient-derived pancreatic tumor model.

  8. Western Kentucky University Research Foundation Biodiesel Project

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Wei-Ping [Principal Investigator; Cao, Yan [Co-Principal Investigator

    2013-03-15

    fermented to create ethanol. In the United States almost all starch ethanol is mainly manufactured from corn grains. The technology for manufacturing corn ethanol can be considered mature as of the late 1980s. In 2005, 14.3 % of the U.S. corn harvest was processed to produce 1.48 x10{sup 10} liters of ethanol, energetically equivalent to 1.72 % of U.S. gasoline usage. Soybean oil is extracted from 1.5 % of the U.S. soybean harvest to produce 2.56 x 10{sup 8} liters of bio-diesel, which was 0.09 % of U.S. diesel usage. However, reaching maximum rates of bio-fuel supply from corn and soybeans is unlikely because these crops are presently major contributors to human food supplies through livestock feed and direct consumption. Moreover, there currently arguments on that the conversion of many types of many natural landscapes to grow corn for feedstock is likely to create substantial carbon emissions that will exacerbate globe warming. On the other hand, there is a large underutilized resource of cellulose biomass from trees, grasses, and nonedible parts of crops that could serve as a feedstock. One of the potentially significant new bio-fuels is so called "cellulosic ethanol", which is dependent on break-down by microbes or enzymes. Because of technological limitations (the wider variety of molecular structures in cellulose and hemicellulose requires a wider variety of microorganisms to break them down) and other cost hurdles (such as lower kinetics), cellulosic ethanol can currently remain in lab scales. Considering farm yields, commodity and fuel prices, farm energy and agrichemical inputs, production plant efficiencies, byproduct production, greenhouse gas (GHG) emissions, and other environmental effects, a life-cycle evaluation of competitive indicated that corn ethanol yields 25 % more energy than the energy invested in its production, whereas soybean bio-diesel yields 93 % more. Relative to the fossil fuels they displace, greenhouse gas emissions are reduced 12 % by the

  9. Manufacturing Initiative

    Data.gov (United States)

    National Aeronautics and Space Administration — The Advanced Manufacturing Technologies (AMT) Project supports multiple activities within the Administration's National Manufacturing Initiative. A key component of...

  10. Evaluation of the crack initiation of curved compact tension specimens of a Zr-2.5Nb pressure tube using the unloading compliance and direct current potential drop methods

    International Nuclear Information System (INIS)

    Kim, Young Suk; Jeong, Hyeon Cheol; Ahn, Sang Bok

    2005-01-01

    The Direct Current Potential Drop(DCPD) method and the Unloading Compliance(UC) method with a crack opening displacement gauge were applied simultaneously to the Zr-2.5Nb Curved Compact Tension (CCT) specimens to determine which of the two methods can precisely determine the crack initiation point and hence the crack length for evaluation of their fracture toughness. The DCPD method detected the crack initiation at a smaller load-time displacement compared to the UC method. As a verification, a direct observation of the fracture surfaces on the curved compact tension specimens was made on the CCT specimens experiencing either 0.8 to 1.0 mm load line displacement or various loads from 50% to 80% of the maximum peak load, or P max . The DCPD method is concluded to be more precise in determining the crack initiation and fracture toughness, J in Zr-2.5Nb CCT specimens than the UC method

  11. 4D co-registration of X-ray and MR-mammograms: initial clinical results and potential incremental diagnostic value.

    Science.gov (United States)

    Dietzel, Matthias; Hopp, Torsten; Ruiter, Nicole V; Kaiser, Clemens G; Kaiser, Werner A; Baltzer, Pascal A

    2015-01-01

    4D co-registration of X-ray- and MR-mammograms (XM and MM) is a new method of image fusion. The present study aims to evaluate its clinical feasibility, radiological accuracy, and potential clinical value. XM and MM of 25 patients were co-registered. Results were evaluated by a blinded reader. Precision of the 4D co-registration was "very good" (mean-score [ms]=7), and lesions were "easier to delineate" (ms=5). In 88.8%, "relevant additional diagnostic information" was present, accounting for a more "confident diagnosis" in 76% (ms=5). 4D co-registration is feasible, accurate, and of potential clinical value. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Initial treatment seeking from professional health care providers for eating disorders: A review and synthesis of potential barriers to and facilitators of "first contact".

    Science.gov (United States)

    Regan, Pamela; Cachelin, Fary M; Minnick, Alyssa M

    2017-03-01

    The objective of this study is to provide a comprehensive review of empirical research exploring barriers to and facilitators of initial treatment seeking ("first contact") from professional health care providers by adults and young adults with eating disorders (EDs). A search of databases PsycINFO and MEDLINE using the terms "treatment" and "eating disorder*" yielded 9,468 peer-reviewed articles published from January 1945 to June 2016. Screening identified 31 articles meeting the following criteria: (1) participants were 16 or older and presented with a self-reported or clinically diagnosed ED; (2) studies focused on (a) initial treatment seeking (b) for an ED (c) from professional health care providers; (3) articles were empirical, and (4) peer reviewed. Quantitative studies revealed few consistent correlates of treatment seeking, perhaps because most variables were examined in only one or two investigations. Variables with some degree of predictive utility (i.e., produced significant results in multiple studies) were age (older), ethnicity (nonethnic minority), ED type (anorexia, purging BN), specific ED-related behaviors (i.e., purging), and time spent on a treatment waitlist following referral (less). Although BMI was one of the most investigated variables, it did not predict treatment seeking. Qualitative studies revealed the following perceived barriers: (1) personal feelings of shame/fear, (2) ED-related beliefs/perceptions, (3) lack of access/availability, and (4) aspects of the treatment process. Perceived facilitators included (1) health-related concerns, (2) emotional distress, and (3) social support. Implications for clinical practice and areas for further research are discussed. Results highlight the need for shared definitions and methodologies across studies of treatment seeking. © 2017 Wiley Periodicals, Inc.

  13. Differentiation potential of human adipose stem cells bioprinted with hyaluronic acid/gelatin-based bioink through microextrusion and visible light-initiated crosslinking.

    Science.gov (United States)

    Sakai, Shinji; Ohi, Hiromi; Hotta, Tomoki; Kamei, Hidenori; Taya, Masahito

    2018-02-01

    Bioprinting has a great potential to fabricate three-dimensional (3D) functional tissues and organs. In particular, the technique enables fabrication of 3D constructs containing stem cells while maintaining cell proliferation and differentiation abilities, which is believed to be promising in the fields of tissue engineering and regenerative medicine. We aimed to demonstrate the utility of the bioprinting technique to create hydrogel constructs consisting of hyaluronic acid (HA) and gelatin derivatives through irradiation by visible light to fabricate 3D constructs containing human adipose stem cells (hADSCs). The hydrogel was obtained from a solution of HA and gelatin derivatives possessing phenolic hydroxyl moieties in the presence of ruthenium(II) tris-bipyridyl dication and sodium ammonium persulfate. hADSCs enclosed in the bioprinted hydrogel construct elongated and proliferated in the hydrogel. In addition, their differentiation potential was confirmed by examining the expression of pluripotency marker genes and cell surface marker proteins, and differentiation to adipocytes in adipogenic differentiation medium. Our results demonstrate the great potential of the bioprinting method and the resultant hADSC-laden HA/gelatin constructs for applications in tissue engineering and regenerative medicine. © 2017 Wiley Periodicals, Inc.

  14. The U.S. Department of Energy's Advanced Fuel Cycle Initiative is evaluating potential costs and benefits of partitioning and transmutation

    International Nuclear Information System (INIS)

    Van Luik, Abraham E.

    2003-01-01

    Abe van Luik (DOE, USA) stated that the U.S. Department of Energy is interested in P and T to the extent that transmutation is technically feasible and will reduce the toxicity of the waste to a point that makes it technically and economically justified. Therefore, research on P and T strategies incorporates the evaluation of its potential costs and benefits. A progress report to Congress (in preparation) will likely state that system studies in the USA and in Europe indicate a preference for reactor based transmutation rather than accelerator-driven systems. DOE proposes isolation of Cs and Sr, the recycling of Pu and Np in LWRs, and later the recycling of minor actinides in fast reactors. The report identifies the high-level waste volume reduction, the easier management of short-term heat load, the reduction of long-term heat load and radiotoxicity, and therefore long-term dose reduction as potential benefits. The goal of ongoing work is to quantify these benefits in order to allow an assessment of which alternatives can be economically useful in increasing the repository capacity, reducing the potential hazard from the repository and reducing uncertainties associated with the performance of the repository. This may, depending on the national nuclear power scenario, delay or avoid the need for a second repository for high-level waste in the USA. Furthermore DOE has received and is evaluating a proposal for simulation-based engineering to integrate all aspects of nuclear energy including reactor technology and waste disposal

  15. Potential geographic "hotspots" for drug-injection related transmission of HIV and HCV and for initiation into injecting drug use in New York City, 2011-2015, with implications for the current opioid epidemic in the US.

    Science.gov (United States)

    Des Jarlais, D C; Cooper, H L F; Arasteh, K; Feelemyer, J; McKnight, C; Ross, Z

    2018-01-01

    We identified potential geographic "hotspots" for drug-injecting transmission of HIV and hepatitis C virus (HCV) among persons who inject drugs (PWID) in New York City. The HIV epidemic among PWID is currently in an "end of the epidemic" stage, while HCV is in a continuing, high prevalence (> 50%) stage. We recruited 910 PWID entering Mount Sinai Beth Israel substance use treatment programs from 2011-2015. Structured interviews and HIV/ HCV testing were conducted. Residential ZIP codes were used as geographic units of analysis. Potential "hotspots" for HIV and HCV transmission were defined as 1) having relatively large numbers of PWID 2) having 2 or more HIV (or HCV) seropositive PWID reporting transmission risk-passing on used syringes to others, and 3) having 2 or more HIV (or HCV) seronegative PWID reporting acquisition risk-injecting with previously used needles/syringes. Hotspots for injecting drug use initiation were defined as ZIP codes with 5 or more persons who began injecting within the previous 6 years. Among PWID, 96% injected heroin, 81% male, 34% White, 15% African-American, 47% Latinx, mean age 40 (SD = 10), 7% HIV seropositive, 62% HCV seropositive. Participants resided in 234 ZIP codes. No ZIP codes were identified as potential hotspots due to small numbers of HIV seropositive PWID reporting transmission risk. Four ZIP codes were identified as potential hotspots for HCV transmission. 12 ZIP codes identified as hotspots for injecting drug use initiation. For HIV, the lack of potential hotspots is further validation of widespread effectiveness of efforts to reduce injecting-related HIV transmission. Injecting-related HIV transmission is likely to be a rare, random event. HCV prevention efforts should include focus on potential hotspots for transmission and on hotspots for initiation into injecting drug use. We consider application of methods for the current opioid epidemic in the US.

  16. Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70

    Directory of Open Access Journals (Sweden)

    Chuturgoon Anil A

    2011-11-01

    Full Text Available Abstract Background Rheumatoid arthritis (RA is a chronic autoimmune disease, which causes synovial damage. Persistence of lymphocyte infiltrates in the rheumatoid synovium has been attributed to abnormal apoptosis. While not comprehensively investigated, perturbations in peripheral blood lymphocyte (PBL apoptosis may also be involved in perpetuation of autoimmune processes in RA. Methods We investigated total, CD4+ and CD19+ PBL apoptosis in our study cohort by monitoring the translocation of phosphatidylserine using the Annexin-V assay. To examine the role of death receptor mediated apoptosis as well as activation-induced-cell-death (AICD, PBLs were labeled with CD95/Fas and CD69 markers and enumerated by flow cytometry. Proteolytic activity of initiator and executioner caspases was determined by luminometry. DNA fragmentation assays were used to examine whether apoptotic signals were transduced to the nucleus. Quantitative PCR arrays were used to investigate apoptotic pathways associated with RA-PBLs. Since heat-shock-protein-70 (HSP70 is an inducible protein which modulates apoptotic signals, we determined HSP70 levels by intra-cellular flow cytometry and western blots. Results The RA-PBLs showed signs of elevated apoptosis whilst in circulation. These include increases in the loss of plasma membrane asymmetry, indicated by increased externalization of phosphatidylserine (especially in B-lymphocytes. RA-PBLs showed a bias to CD95/Fas mediated apoptotic pathways, but low levels of the CD69 marker suggested that this was not associated with immune activation. Although downstream markers of apoptosis such as caspase-3/7 activity, were increased, no DNA fragmentation was observed in RA-PBLs. Interestingly, elevated levels of apoptosis did not correlate with absolute lymphocyte counts in RA patients. Levels of HSP70 were highly elevated in RA-PBLs compared to controls. Conclusion The results suggest that while apoptosis may be initiated in RA

  17. Potential change in flaw geometry of an initially shallow finite-length surface flaw during a pressurized-thermal-shock transient

    International Nuclear Information System (INIS)

    Shum, D.K.; Bryson, J.W.; Merkle, J.G.

    1993-09-01

    This study presents preliminary estimates on whether an shallow, axially oriented, inner-surface finite-length flaw in a PWR-RPV would tend to elongate in the axial direction and/or deepen into the wall of the vessel during a postulated PTS transient. Analysis results obtained based on the assumptions of (1) linear-elastic material response, and (2) cladding with same toughness as the base metal, indicate that a nearly semicircular flaw would likely propagate in the axial direction followed by propagation into the wall of the vessel. Note that these results correspond to initiation within the lower-shelf fracture toughness temperature range, and that their general validity within the lower-transition temperature range remains to be determined. The sensitivity of the numerical results aid conclusions to the following analysis assumptions are evaluated: (1) reference flaw geometry along the entire crack front and especially within the cladding region; (2) linear-elastic vs elastic-plastic description of material response; and (3) base-material-only vs bimaterial cladding-base vessel-model assumption. The sensitivity evaluation indicates that the analysis results are very sensitive to the above assumptions

  18. The Collective Impact Model and Its Potential for Health Promotion: Overview and Case Study of a Healthy Retail Initiative in San Francisco.

    Science.gov (United States)

    Flood, Johnna; Minkler, Meredith; Hennessey Lavery, Susana; Estrada, Jessica; Falbe, Jennifer

    2015-10-01

    As resources for health promotion become more constricted, it is increasingly important to collaborate across sectors, including the private sector. Although many excellent models for cross-sector collaboration have shown promise in the health field, collective impact (CI), an emerging model for creating larger scale change, has yet to receive much study. Complementing earlier collaboration approaches, CI has five core tenets: a shared agenda, shared measurement systems, mutually reinforcing activities, continuous communication, and a central infrastructure. In this article, we describe the CI model and its key dimensions and constructs. We briefly compare CI to community coalition action theory and discuss our use of the latter to provide needed detail as we apply CI in a critical case study analysis of the Tenderloin Healthy Corner Store Coalition in San Francisco, California. Using Yin's multimethod approach, we illustrate how CI strategies, augmented by the community coalition action theory, are being used, and with what successes or challenges, to help affect community- and policy-level change to reduce tobacco and alcohol advertising and sales, while improving healthy, affordable, and sustainable food access. We discuss the strengths and weaknesses of CI as a framework for health promotion, as well as the benefits, challenges, and initial outcomes of the healthy retail project and its opportunities for scale-up. Implications for health promotion practice and research also are discussed. © 2015 Society for Public Health Education.

  19. Adult Fanniidae associated to pig carcasses during the winter season in a semiarid environment: initial examination of their potential as complementary PMI indicators.

    Science.gov (United States)

    Aballay, Fernando H; Domínguez, M Cecilia; Fernández Campón, Florencia

    2012-06-10

    Besides the dominant necrophagous dipteran of the families Sarcophagidae and Calliphoridae usually used for post mortem interval (PMI) estimations, species of other families such as Fanniidae have frequently been reported in forensic studies. Though less abundant, these species are prevalent in decomposing carcasses with most reports being anecdotal. In this study we identified adults of the fly family Fanniidae associated to pig carcasses located under different local environmental conditions (sun and shade) in a semiarid area at Mendoza, Argentina during the winter season. We examined the potential of species of this family as indicators of PMI by measuring abundance, time of occurrence and residency time at the carcasses. We identified six species of Fanniidae: Euryomma peregrinum Meigen, Fannia albitarsis Stein, Fannia femoralis Stein, Fannia fusconotata Rondani, Fannia heydenii Wiedemann and Fannia sanihue Domínguez and Aballay. Overall, fly abundance was higher at the sunlit than at the shaded carcass. The most abundant species at the sun was F. fusconotata while at the shaded carcass F. femoralis was the most abundant species. Based on their residency time, however, species with higher potential as PMI indicators seem to be F. heydenii and F. sanihue as their residency time at the carcass was restricted to a short period of the decomposition process. Other species were present throughout most of the decomposition process or in such a low abundance (E. peregrinum) that they were not useful as indicators. These preliminary results indicate that adults of some species of Fanniidae could act as a good complementary indicator species during the winter season. In particular, F. heydenii and F. sanihue should be the focus of further studies which should also expand to other seasons. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  20. Non-isomorphic radial wavenumber dependencies of residual zonal flows in ion and electron Larmor radius scales, and effects of initial parallel flow and electromagnetic potentials in a circular tokamak

    Science.gov (United States)

    Yamagishi, Osamu

    2018-04-01

    Radial wavenumber dependencies of the residual zonal potential for E × B flow in a circular, large aspect ratio tokamak is investigated by means of the collisionless gyrokinetic simulations of Rosenbluth-Hinton (RH) test and the semi-analytic approach using an analytic solution of the gyrokinetic equation Rosenbluth and Hinton (1998 Phys. Rev. Lett. 80 724). By increasing the radial wavenumber from an ion Larmor radius scale {k}r{ρ }i≲ 1 to an electron Larmor radius scale {k}r{ρ }e≲ 1, the well-known level ˜ O[1/(1+1.6{q}2/\\sqrt{r/{R}0})] is retained, while the level remains O(1) when the wavenumber is decreased from the electron to the ion Larmor radius scale, if physically same adiabatic assumption is presumed for species other than the main species that is treated kinetically. The conclusion is not modified by treating both species kinetically, so that in the intermediate scale between the ion and electron Larmor radius scale it seems difficult to determine the level uniquely. The toroidal momentum conservation property in the RH test is also investigated by including an initial parallel flow in addition to the perpendicular flow. It is shown that by taking a balance between the initial parallel flow and perpendicular flows which include both E × B flow and diamagnetic flow in the initial condition, the mechanical toroidal angular momentum is approximately conserved despite the toroidal symmetry breaking due to the finite radial wavenumber zonal modes. Effect of electromagnetic potentials is also investigated. When the electromagnetic potentials are applied initially, fast oscillations which are faster than the geodesic acoustic modes are introduced in the decay phase of the zonal modes. Although the residual level in the long time limit is not modified, this can make the time required to reach the stationary zonal flows longer and may weaken the effectiveness of the turbulent transport suppression by the zonal flows.

  1. Unilateral initiatives

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    This paper reports on arms control which is generally thought of in terms of formal negotiations with an opponent, with the resulting agreements embodied in a treaty. This is not surprising, since arms control discussions between opponents are both important and politically visible. There are, however, strong reasons for countries to consider and frequently take unilateral initiatives. To do so is entirely consistent with the established major precepts of arms control which state that arms control is designed to reduce the risk of war, the costs of preparing for war, and the death and destruction if war should come. Unilateral initiatives on what weapons are purchased, which ones are eliminated and how forces are deployed can all relate to these objectives. There are two main categories of motives for unilateral initiatives in arms control. In one category, internal national objectives are the dominant, often sole, driving force; the initiative is undertaken for our own good

  2. Ports Initiative

    Science.gov (United States)

    EPA's Ports Initiative works in collaboration with the port industry, communities, and government to improve environmental performance and increase economic prosperity. This effort helps people near ports breath cleaner air and live better lives.

  3. GIS-NaP1 zeolite microspheres as potential water adsorption material: Influence of initial silica concentration on adsorptive and physical/topological properties.

    Science.gov (United States)

    Sharma, Pankaj; Song, Ju-Sub; Han, Moon Hee; Cho, Churl-Hee

    2016-03-11

    GIS-NaP1 zeolite samples were synthesized using seven different Si/Al ratios (5-11) of the hydrothermal reaction mixtures having chemical composition Al2O3:xSiO2:14Na2O:840H2O to study the impact of Si/Al molar ratio on the water vapour adsorption potential, phase purity, morphology and crystal size of as-synthesized GIS-NaP1 zeolite crystals. The X-ray diffraction (XRD) observations reveal that Si/Al ratio does not affect the phase purity of GIS-NaP1 zeolite samples as high purity GIS-NaP1 zeolite crystals were obtained from all Si/Al ratios. Contrary, Si/Al ratios have remarkable effect on the morphology, crystal size and porosity of GIS-NaP1 zeolite microspheres. Transmission electron microscopy (TEM) evaluations of individual GIS-NaP1 zeolite microsphere demonstrate the characteristic changes in the packaging/arrangement, shape and size of primary nano crystallites. Textural characterisation using water vapour adsorption/desorption, and nitrogen adsorption/desorption data of as-synthesized GIS-NaP1 zeolite predicts the existence of mix-pores i.e., microporous as well as mesoporous character. High water storage capacity 1727.5 cm(3) g(-1) (138.9 wt.%) has been found for as-synthesized GIS-NaP1 zeolite microsphere samples during water vapour adsorption studies. Further, the total water adsorption capacity values for P6 (1299.4 mg g(-1)) and P7 (1388.8 mg g(-1)) samples reveal that these two particular samples can absorb even more water than their own weights.

  4. In vivo evaluation of the genetic toxicity of Rubus niveus Thunb. (Rosaceae) extract and initial screening of its potential chemoprevention against doxorubicin-induced DNA damage.

    Science.gov (United States)

    Tolentino, Flora; Araújo, Priscila Alves de; Marques, Eduardo de Souza; Petreanu, Marcel; Andrade, Sérgio Faloni de; Niero, Rivaldo; Perazzo, Fábio F; Rosa, Paulo César Pires; Maistro, Edson Luis

    2015-04-22

    Rubus niveus Thunb. plant belongs to Rosaceae family and have been used traditionally to treat wounds, burns, inflammation, dysentery, diarrhea and for curing excessive bleeding during menstrual cycle. The present study was undertaken to investigate the in vivo genotoxicity of Rubus niveus aerial parts extract and its possible chemoprotection on doxorubicin (DXR)-induced DNA damage. In parallel, the main phytochemicals constituents in the extract were determined. The animals were exposed to the extract for 24 and 48 h, and the doses selected were 500, 1000 and 2000 mg/kg b.w. administered by gavage alone or prior to DXR (30 mg/kg b.w.) administered by intraperitoneal injection. The endpoints analyzed were DNA damage in bone marrow and peripheral blood cells assessed by the alkaline alkaline (pH>13) comet assay and bone marrow micronucleus test. The results of chemical analysis of the extract showed the presence of tormentic acid, stigmasterol, quercitinglucoronide (miquelianin) and niga-ichigoside F1 as main compounds. Both cytogenetic endpoints analyzed showed that there were no statistically significant differences (p>0.05) between the negative control and the treated groups with the two higher doses of Rubus niveus extract alone, demonstrating absence of genotoxic and mutagenic effects. Aneugenic/clastogenic effect was observed only at 2000 mg/kg dose. On the other hand, in the both assays and all tested doses were observed a significant reduction of DNA damage and chromosomal aberrations in all groups co-treated with DXR and extract compared to those which received only DXR. These results indicate that Rubus niveus aerial parts extract did not revealed any genotoxic effect, but presented some aneugenic/clastogenic effect at higher dose; and suggest that it could be a potential adjuvant against development of second malignant neoplasms caused by the cancer chemotherapic DXR. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  5. GIS-NaP1 zeolite microspheres as potential water adsorption material: Influence of initial silica concentration on adsorptive and physical/topological properties

    Science.gov (United States)

    Sharma, Pankaj; Song, Ju-Sub; Han, Moon Hee; Cho, Churl-Hee

    2016-01-01

    GIS-NaP1 zeolite samples were synthesized using seven different Si/Al ratios (5–11) of the hydrothermal reaction mixtures having chemical composition Al2O3:xSiO2:14Na2O:840H2O to study the impact of Si/Al molar ratio on the water vapour adsorption potential, phase purity, morphology and crystal size of as-synthesized GIS-NaP1 zeolite crystals. The X-ray diffraction (XRD) observations reveal that Si/Al ratio does not affect the phase purity of GIS-NaP1 zeolite samples as high purity GIS-NaP1 zeolite crystals were obtained from all Si/Al ratios. Contrary, Si/Al ratios have remarkable effect on the morphology, crystal size and porosity of GIS-NaP1 zeolite microspheres. Transmission electron microscopy (TEM) evaluations of individual GIS-NaP1 zeolite microsphere demonstrate the characteristic changes in the packaging/arrangement, shape and size of primary nano crystallites. Textural characterisation using water vapour adsorption/desorption, and nitrogen adsorption/desorption data of as-synthesized GIS-NaP1 zeolite predicts the existence of mix-pores i.e., microporous as well as mesoporous character. High water storage capacity 1727.5 cm3 g−1 (138.9 wt.%) has been found for as-synthesized GIS-NaP1 zeolite microsphere samples during water vapour adsorption studies. Further, the total water adsorption capacity values for P6 (1299.4 mg g−1) and P7 (1388.8 mg g−1) samples reveal that these two particular samples can absorb even more water than their own weights. PMID:26964638

  6. Initial results from dissolution rate testing of N-Reactor spent fuel over a range of potential geologic repository aqueous conditions

    International Nuclear Information System (INIS)

    Gray, W.J.; Einziger, R.E.

    1998-04-01

    Hanford N-Reactor spent nuclear fuel (HSNF) may ultimately be placed in a geologic repository for permanent disposal. To determine whether the engineered barrier system that will be designed for emplacement of light-water-reactor (LWR) spent fuel will also suffice for HSNF, aqueous dissolution rate measurements were conducted on the HSNF. The purpose of these tests was to determine whether HSNF dissolves faster or slower than LWR spent fuel under some limited repository-relevant water chemistry conditions. The tests were conducted using a flowthrough method that allows the dissolution rate of the uranium matrix to be measured without interference by secondary precipitation reactions that would confuse interpretation of the results. Similar tests had been conducted earlier with LWR spent fuel, thereby allowing direct comparisons. Two distinct corrosion modes were observed during the course of these 12 tests. The first, Stage 1, involved no visible corrosion of the test specimen and produced no undissolved corrosion products. The second, Stage 2, resulted in both visible corrosion of the test specimen and left behind undissolved corrosion products. During Stage 1, the rate of dissolution could be readily determined because the dissolved uranium and associated fission products remained in solution where they could be quantitatively analyzed. The measured rates were much faster than has been observed for LWR spent fuel under all conditions tested to date when normalized to the exposed test specimen surface areas. Application of these results to repository conditions, however, requires some comparison of the physical conditions of the different fuels. The surface area of LWR fuel that could potentially be exposed to repository groundwater is estimated to be approximately 100 times greater than HSNF. Therefore, when compared on the basis of mass, which is more relevant to repository conditions, the HSNF and LWR spent fuel dissolve at similar rates

  7. Metformin as an initial adjunct to low-dose liraglutide enhances the weight-decreasing potential of liraglutide in obese polycystic ovary syndrome: Randomized control study.

    Science.gov (United States)

    Jensterle, Mojca; Goricar, Katja; Janez, Andrej

    2016-04-01

    Liraglutide (LIRA) treatment is associated with the dose-dependent reduction of weight. Higher doses are more effective than lower doses, although higher doses are also more poorly tolerated. Metformin may enhance the weight-lowering potential of LIRA via the stimulatory modulation of incretin in addition to its direct beneficial effects in PCOS. The aim of the present study was to evaluate whether metformin as an adjunct to low-dose LIRA affects body weight with increased efficacy compared with low-dose LIRA alone in obese patients with PCOS. In a 12-week study, 44 obese women with PCOS were randomly offered either combined treatment (COMBO) with 1,000 mg metformin twice a day and 1.2 mg LIRA once a day, or treatment with 1.2 mg LIRA alone. The primary outcome of treatment was an alteration in the levels of obesity. A total of 43 patients [aged 30.3±4.4 years; body mass index (BMI) 37.2±4.5 kg/m 2 ; mean ± standard deviation] completed the study. The subjects treated with COMBO lost on average 6.2±2.4 kg compared with a 3.8±3.5 kg weight loss in the patients treated with LIRA alone (P=0.024). The BMI decreased by 2.2±0.8 kg/m 2 in patients treated with COMBO and by 1.4±1.2 kg/m 2 in patients treated with LIRA alone (P=0.024). A clinically significant ≥5% weight reduction was achieved in 59.1% of patients treated with COMBO and 42.9% of patients treated with LIRA alone. Reductions in glucose levels following oral glucose tolerance testing, as well as in androstenedione levels in the COMBO group were significantly greater compared with those in the LIRA group. The side effects were mild and transient in the two treatment groups. A combination of metformin and low-dose LIRA was more effective than low-dose LIRA alone in reducing body weight in obese patients with PCOS.

  8. Initial Study

    DEFF Research Database (Denmark)

    Torp, Kristian

    2009-01-01

    increased. In the initial study presented here, the time it takes to pass an intersection is studied in details. Two major signal-controlled four-way intersections in the center of the city Aalborg are studied in details to estimate the congestion levels in these intersections, based on the time it takes...

  9. BioTfueL Project: Targeting the Development of Second-Generation Bio-diesel and Bio-jet Fuels

    International Nuclear Information System (INIS)

    Viguie, J.C.; Ullrich, N.; Porot, P.; Bournay, L.; Hecquet, M.; Rousseau, J.

    2013-01-01

    2. generation biofuels will have an important part to take in the energy transition as far as fuels are concerned. Using non edible biomass, they will avoid any direct competition with food usage. Within second generation biofuels, the BTL route consists in the production of middle distillates (Diesel and jet fuel) via gasification and Fischer-Tropsch (FT) synthesis. These fuels are called 'drop in' fuels; this means that to be used they technically do not request any modification in the vehicle whatever the blending rate with conventional fuels. This route is currently at the pre-industrial phase where demonstration is required. This article presents the BioTfueL project which has been created by Axens, CEA, IFP Energies Nouvelles, Sofiproteol, ThyssenKrupp Uhde and Total. This project is focused on the original concept of co-processing (biomass can be gasified together with fossil feedstock) and proposes to develop and demonstrate a full process chain to be commercialized worldwide via licensing. (authors)

  10. Optimization of the production of bio diesel from egusi melon (Colocynthis Citrullus L.) oil using response surface methodology

    International Nuclear Information System (INIS)

    Giwa, S.O.; Chuah, L.A.; Nor Mariah Adam

    2009-01-01

    Full text: In the present work, the response surface methodology (RSM), based on a central composite design (CCD), was used to determine the optimum conditions for the transesterification of crude egusi melon (Colocynthis citrullus L.) seed oil. Three process factors were evaluated at three levels (2 3 experimental design): the oil/ methanol molar ratio, the amount of catalyst in relation to the oil mass, and the reaction temperature. The amounts of catalyst and reaction temperature were the most significant (P 2 = 0.98). Using multiple regression analysis a quadratic polynomial equation was obtained for predicting methyl ester yield of the transesterification reaction. The squared terms of catalyst amount (P < 0.0001) and oil/ methanol molar ratio (P < 0.0072) showed significant effects on esters yield. The optimum reaction conditions for synthesis of EMOME were 1:6.55 oil-to-methanol molar ratio, 1.22 % catalyst amounts, and 65 degree Celsius reaction temperature resulting in a yield of 84.01 %. Using these optimal factor values under experimental conditions a methyl esters yield of 84.04 % was obtained on an average, and this value was well within the range predicted by the model. RSM was found to be a suitable technique for optimizing transesterification of egusi melon seed oil. Fuel properties of EMOME measured according to accepted methods were found to satisfy all prescribed ASTM (D 6751) and EN 14214 specifications. (author)

  11. Corrosion behavior of stainless steel in bio diesel production; Comportamento quanto a corrosao de acos inoxidaveis na producao do biodiesel

    Energy Technology Data Exchange (ETDEWEB)

    Miranda, E.F. de [ArcelorMittal Sao Paulo Servicos, SP (Brazil); Moreira, M.C.; Lebrao, S.M.G. [Centro Universitario do Instituto Maua de Tecnologia, Sao Paulo, SP (Brazil)], e-mail: susana.lebrao@maua.br

    2010-07-01

    Biodiesel has become more attractive due to the benefits to the environment, mainly because it is a renewable resource. However, the main barrier to biodiesel is it cost. One factor which is charged to marketing is the use of stainless steel throughout the production line, the most used is AISI 304. To evaluate more economical stainless steels, weight loss and stress corrosion tests were performed on samples of AISI 304 and 439 in methanol PS X30% sodium methylate solution, crude soybean oil, glycerol and biodiesel for about two hundred and fifty days. The mass loss was negligible, and there was complete absence of pitting and stress corrosion cracking in all media studied, showing that both alloys are suitable for the manufacture of such equipment. (author)

  12. Thermal and electrical properties of polymers produced from methyl oleate and bio diesel of sunflower and linseed oils

    International Nuclear Information System (INIS)

    Nicolau, Aline; Reiznautt, Quelen B.; Martini, Denise D.; Samios, Dimitrios

    2011-01-01

    Polyesters were prepared from epoxidized biodiesel with different unsaturation degrees. The polymerisation was performed using epoxidized methyl esters of oleic acid (EPOAME), sunflower oil (EPSOME) and linseed oil (EPLOME) with cis-1,2-cyclohexanedicarboxylic anhydride and triethylamine. Differential Scanning Calorimetry (DSC) demonstrated that reaction enthalpy was proportional to the unsaturation degree of each methyl ester. With an increase in unsaturation degree, the activation energy linearly decreased. The intermediate structures and the polyesters were characterised using Nuclear Magnetic Resonance (NMR) techniques. The molecular weight of the polymers synthesised with EPOAME, EPSOME and EPLOME were, respectively, 2.5x103, 5.3x103 and 14x103 g/mol. The glass transition of the product obtained from EPOAME was -59 degree C. The polymers based on EPSOME and EPLOME exhibited higher Tg values, which were -11 and -6 degree C, respectively. Electric impedance measurements of the polyesters showed that an increase in unsaturation degree resulted in an increase in resistivity and a decrease in capacitance. (author)

  13. Experimental Investigation of Performance and emission characteristics of Various Nano Particles with Bio-Diesel blend on Di Diesel Engine

    Science.gov (United States)

    Karthik, N.; Goldwin Xavier, X.; Rajasekar, R.; Ganesh Bairavan, P.; Dhanseelan, S.

    2017-05-01

    Present study provides the effect of Zinc Oxide (ZnO) and Cerium Oxide (CeO2) nanoparticles additives on the Performance and emission uniqueness of Jatropha. Jatropha blended fuel is prepared by the emulsification technique with assist of mechanical agitator. Nano particles (Zinc Oxide (ZnO)) and Cerium Oxide (CeO2)) mixed with Jatropha blended fuel in mass fraction (100 ppm) with assist of an ultrasonicator. Experiments were conducted in single cylinder constant speed direct injection diesel engine for various test fuels. Performance results revealed that Brake Thermal Efficiency (BTE) of Jatropha blended Cerium Oxide (B20CE) is 3% and 11% higher than Jatropha blended zinc oxide (B20ZO) and Jatropha blended fuel (B20) and 4% lower than diesel fuel (D100) at full load conditions. Emission result shows that HC and CO emissions of Jatropha blended Cerium Oxide (B20CE) are (6%, 22%, 11% and 6%, 15%, 12%) less compared with Jatropha blended Zinc Oxide (B20ZO), diesel (D100) and Jatropha blended fuel (B20) at full load conditions. NOx emissions of Jatropha blended Cerium Oxide is 1 % higher than diesel fuel (D100) and 2% and 5% lower than Jatropha blended Zinc Oxide, and jatropha blended fuel.

  14. Semivolatile organic compound emissions from heavy-duty trucks operating on diesel and bio-diesel fuel blends

    Science.gov (United States)

    This study measured semivolatile organic compounds (SVOCs) in particle matter (PM) emitted from three heavy-duty trucks equipped with modern after-treatment technologies. Emissions testing was conducted as described by the George et al. VOC study also presented as part of this se...

  15. Characterization and speciation of fine particulate matter inside the public transport buses running on bio-diesel.

    Science.gov (United States)

    2009-09-01

    Air pollution with respect to particulate matter was investigated in Toledo, Ohio, USA, a : city of approximately 300,000, in 2009. Two study buses were selected to reflect typical : exposure conditions of passengers while traveling in the bus. Monit...

  16. Performance and emission parameters of single cylinder diesel engine using castor oil bio-diesel blended fuels

    Science.gov (United States)

    Rahimi, A.; Ghobadian, B.; Najafi, G.; Jaliliantabar, F.; Mamat, R.

    2015-12-01

    The purpose of this study is to investigate the performance and emission parameters of a CI single cylinder diesel engine operating on biodiesel-diesel blends (B0, B5, B10, B15 and E20: 20% biodiesel and 80% diesel by volume). A reactor was designed, fabricated and evaluated for biodiesel production. The results showed that increasing the biodiesel content in the blend fuel will increase the performance parameters and decrease the emission parameters. Maximum power was detected for B0 at 2650 rpm and maximum torque was belonged to B20 at 1600 rpm. The experimental results revealed that using biodiesel-diesel blended fuels increased the power and torque output of the engine. For biodiesel blends it was found that the specific fuel consumption (sfc) was decreased. B10 had the minimum amount for sfc. The concentration of CO2 and HC emissions in the exhaust pipe were measured and found to be decreased when biodiesel blends were introduced. This was due to the high oxygen percentage in the biodiesel compared to the net diesel fuel. In contrast, the concentration of CO and NOx was found to be increased when biodiesel is introduced.

  17. Access to Anti-smoking Information among School Children and its Potential Impact on Preventing Smoking Initiation: Results from the Global Youth Tobacco Use Survey (GYTS) 2014 in Viet Nam.

    Science.gov (United States)

    Minh, Hoang Van; Minh, Hoang Van; Giang, Kim Bao; Hai, Phan Thi; Hoang, Trinh Dinh; Huyen, Doan Thu; Khue, Luong Ngoc; Linh, Nguyen Thuy; Lam, Nguyen Tuan; Nga, Pham Thi Quynh

    2016-01-01

    Scientific evidence on all aspects of smoking amongst youth is very important for designing appropriate interventions to reduce smoking among this vulnerable population. This paper describes current access to antismoking information among school children aged 13 to 15 years in Vietnam in 2014 and examines its potential impact on preventing smoking initiation. The data used in this paper were obtained from the 2014 Global Youth Tobacco Survey (GYTS) in Vietnam. Students were asked questions about their level of awareness of anti-smoking information from various sources in the past 30 days and about lessons in school regarding the dangers of tobacco use during the last 12 months. Those who have never smoked were asked "whether or not they thought about avoiding cigarettes because of health warnings on cigarette packages" and answers were analyzed in combination with data on access to anti-smoking information from other sources. The prevalence of exposure to antismoking campaigns was high among school children in Viet Nam: 55.3% of current smokers reported thoughts of smoking cessation because of health warnings on cigarette packages; 60.5% of never smokers avoided initiating smoking because of the same health warnings. The potential impact of graphic health warnings to prevent school-aged children from smoking initiation would be stronger if there was concurrent access to anti-smoking programs on the dangers of tobacco use in schools. However, school education for tobacco prevention and control has not been as strong as expected. A more comprehensive school curriculum on tobacco prevention and control is recommended to reinforce antismoking messages among school children.

  18. Openness initiative

    International Nuclear Information System (INIS)

    Duncan, S.S.

    1995-01-01

    Although antinuclear campaigns seem to be effective, public communication and education efforts on low-level radioactive waste have mixed results. Attempts at public information programs on low-level radioactive waste still focus on influencing public opinion. A question then is: open-quotes Is it preferable to have a program focus on public education that will empower individuals to make informed decisions rather than trying to influence them in their decisions?close quotes To address this question, a case study with both quantitative and qualitative data will be used. The Ohio Low-Level Radioactive Waste Education Program has a goal to provide people with information they want/need to make their own decisions. The program initiated its efforts by conducting a statewide survey to determine information needed by people and where they turned for that information. This presentation reports data from the survey and then explores the program development process in which programs were designed and presented using the information. Pre and post data from the programs reveal attitude and knowledge shifts

  19. Openness initiative

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, S.S. [Los Alamos National Lab., NM (United States)

    1995-12-31

    Although antinuclear campaigns seem to be effective, public communication and education efforts on low-level radioactive waste have mixed results. Attempts at public information programs on low-level radioactive waste still focus on influencing public opinion. A question then is: {open_quotes}Is it preferable to have a program focus on public education that will empower individuals to make informed decisions rather than trying to influence them in their decisions?{close_quotes} To address this question, a case study with both quantitative and qualitative data will be used. The Ohio Low-Level Radioactive Waste Education Program has a goal to provide people with information they want/need to make their own decisions. The program initiated its efforts by conducting a statewide survey to determine information needed by people and where they turned for that information. This presentation reports data from the survey and then explores the program development process in which programs were designed and presented using the information. Pre and post data from the programs reveal attitude and knowledge shifts.

  20. Initiative hard coal; Initiative Steinkohle

    Energy Technology Data Exchange (ETDEWEB)

    Leonhardt, J.

    2007-08-02

    In order to decrease the import dependence of hard coal in the European Union, the author has submitted suggestions to the director of conventional sources of energy (directorate general for energy and transport) of the European community, which found a positive resonance. These suggestions are summarized in an elaboration 'Initiative Hard Coal'. After clarifying the starting situation and defining the target the presupposition for a better use of hard coal deposits as raw material in the European Union are pointed out. On that basis concrete suggestions for measures are made. Apart from the conditions of the deposits it concerns thereby also new mining techniques and mining-economical developments, connected with tasks for the mining-machine industry. (orig.)

  1. Biology and genetic improvement of Jatropha curcas L.: A review

    Energy Technology Data Exchange (ETDEWEB)

    Divakara, B.N.; Upadhyaya, H.D.; Gowda, C.L. Laxmipathi [Global Theme on Crop Improvement, International Crops Research Institute for the Semi Arid Tropics, Patancheru - 502 324, Hyderabad, Andhra Pradesh (India); Wani, S.P. [Global Theme of Agroecosystems, International Crops Research Institute for the Semi Arid Tropics, Patancheru - 502 324, Hyderabad, Andhra Pradesh (India)

    2010-03-15

    Bio-diesel is a fast-developing alternative fuel in many developed and developing countries of the world. The bio-diesel production from vegetable oils during 2004-2005 was estimated 2.36 million tonnes globally. Of this, EU countries accounted for about 82% and USA about 6%. Global bio-diesel production is set to reach some 24 billion litres by 2017. Shortage of edible oil for human consumption in developing countries does not favour its use for bio-diesel production. Hence non-edible oil from crops like Jatropha (Jatrophacurcas) and Pongamia (Pongamiapinnata) is favoured for bio-diesel production and the trend is expected to continue. Especially J. curcas has gained attention in tropical and sub-tropical countries and has spread beyond its centre of origin, because of its hardiness, easy propagation, drought endurance, high oil content, rapid growth, adaptation to wide agro-climatic conditions, and multiple uses of plant as a whole. The full potential of J. curcas has not been realized due to several technological and economic reasons. One of the major reasons is the lack of high yielding varieties with high oil content. In this review, we attempt to discuss the currently available information on Jatropha species identity, taxonomy and description, distribution and ecological requirements of the species, possibilities of exploitation of genetic potentiality, exploitation of existing diversity for yield and oil content by direct selection, hybridization and creation of diversity by mutation, and biotechnological interventions. (author)

  2. Atmospheric chemistry of CH3O(CF2CF2O)(n)CH3 (n=1-3): Kinetics and mechanism of oxidation initiated by Cl atoms and OH radicals, IR spectra, and global warmin potentials

    DEFF Research Database (Denmark)

    Andersen, Mads Peter Sulbæk; Hurley, MD; Wallington, TJ

    2004-01-01

    Smog chambers equipped with FTIR spectrometers were used to study the Cl atom and OH radical initiated oxidation of CH3O(CF2CF2O)(n)CH3 (n = 1-3) in 720 +/- 20 Torr of air at 296 +/- 3 K. Relative rate techniques were used to measure k(Cl + CH3O(CF2CF2O)(n)CH3) (3.7 +/- 10.7) x 10(-13) and k......(OH + CH3O(CF2CF2O)(n)CH3) = (2.9 +/- 0.5) x 10(-11) cm(3) molecule(-1) s(-1) leading to an estimated atmospheric lifetime of 2 years for CH3O(CF2CF2O),CH3. The Cl initiated oxidation of CH3O(CF2CF2O),CH3 in air diluent gives CH3O(CF2CF2O)(n)C(O)H in a yield which is indistinguishable from 100 Further...... oxidation leads to the diformate, H(O)CO(CF2CF2O)(n)C(O)H. A rate constant of k(Cl + CH3O(CF2CF2O)(n)CHO) = (1.81 +/- 0.36) x 10(-13) cm(3) molecule(-1) s-1 was determined. Quantitative infrared spectra for CH3O(CF2CF2O)(n)CH3 (n = 1-3) were recorded and used to estimate halocarbon global warming potentials...

  3. Defense Acquisition Initiatives Review: An Assessment of Extant Initiatives

    National Research Council Canada - National Science Library

    Porter, Gene; Berteau, David; Christle, Gary; Mandelbaum, Jay; Diehl, Richard

    2005-01-01

    ...) to identify and analyze a subset of initiatives that the team finds to have potential for near term management emphasis that could provide visible improvements to the much criticized Defense acquisition system...

  4. Evaluation of the crack initiation of curved compact tension specimens of a Zr-2.5Nb pressure tube using the unloading compliance and direct current potential drop methods

    International Nuclear Information System (INIS)

    Jeong, Hyeon Cheol; Ahn, Sang Bok; Park, Joong Chul; Kim, Young Suk

    2005-01-01

    Zr-2.5Nb pressure tubes, carrying fuel bundles and heavy water coolant inside, degrade due to neutron irradiation and hydrogen embrittlement during their operation in heavy water reactors. The safety criterion for the Zr-2.5Nb tubes to meet is a leak-before-break (LBB) requirement. To evaluate a safety margin related to the LBB criterion, facture toughness of the pressure tubes are to be determined periodically with their operational time. For a reliable evaluation of the LBB safety criterion of the pressure tubes, it is required to precisely determine their fracture toughness. Since the fracture toughness or J of the pressure tubes is determined only by the extended crack length, it is important to reliably and precisely evaluate the advanced crack length. However, the problem lies with the detection of the crack opening point because prior plastic deformation before a start of the crack makes it difficult. The aim of this work is to evaluate which method can define the crack initiation point in the Zr- 2.5Nb compact tension specimens more precisely between the unloading compliance method with a crack opening displacement (COD) gauge and the direct current potential drop (DCPD) methods

  5. Potential and Challenges of Low-Cost and High-Tech Crowd-sensing Approaches in Hydrometeorology for Better Water Resources Management - Insights and Learnings from the Global iMoMo Initiative

    Science.gov (United States)

    Siegfried, Tobias

    2016-04-01

    In developing and transition countries and despite significant global investments in hydrometeorology, data on water remain scarce/fragmented. One key reason is that traditional sensing in hydrology, hydro- and agro-meteorology does not scale because of high investment costs and difficult maintenance of traditional technology, esp. in remote and/or poor regions. Even where there are data, these are often difficult to access and interpret for local stakeholders due outdated data transmission and the lack of access to modern tools for data management/analysis/synthesis and exchange. In recent years, there have been substantial technology developments in environmental sensing and mobile communication technology that enable the application and deployment of affordable and scalable high-tech solutions for better water monitoring at different scales (local to transboundary levels). The WMO is acknowledging and promoting the potential for application of these technologies. One key aspect is to anchor these technologies in local communities that perform crowd-sensing tasks on a regular basis. The merits as well as challenges (including introduction of human factor, less accuracy as compared to traditional sensing, intermittency of data, …) of such approaches will be discussed in the context of the WMO-led Global iMoMo Initiative and its numerous activities on the ground in Eastern and Southern Africa as well as in Central Asia.

  6. Initiation devices, initiation systems including initiation devices and related methods

    Energy Technology Data Exchange (ETDEWEB)

    Daniels, Michael A.; Condit, Reston A.; Rasmussen, Nikki; Wallace, Ronald S.

    2018-04-10

    Initiation devices may include at least one substrate, an initiation element positioned on a first side of the at least one substrate, and a spark gap electrically coupled to the initiation element and positioned on a second side of the at least one substrate. Initiation devices may include a plurality of substrates where at least one substrate of the plurality of substrates is electrically connected to at least one adjacent substrate of the plurality of substrates with at least one via extending through the at least one substrate. Initiation systems may include such initiation devices. Methods of igniting energetic materials include passing a current through a spark gap formed on at least one substrate of the initiation device, passing the current through at least one via formed through the at least one substrate, and passing the current through an explosive bridge wire of the initiation device.

  7. Community Rates of Breastfeeding Initiation.

    Science.gov (United States)

    Grubesic, Tony H; Durbin, Kelly M

    2016-11-01

    Breastfeeding initiation rates vary considerably across racial and ethnic groups, maternal age, and education level, yet there are limited data concerning the influence of geography on community rates of breastfeeding initiation. This study aimed to describe how community rates of breastfeeding initiation vary in geographic space, highlighting "hot spots" and "cool spots" of initiation and exploring the potential connections between race, socioeconomic status, and urbanization levels on these patterns. Birth certificate data from the Kentucky Department of Health for 2004-2010 were combined with county-level geographic base files, Census 2010 demographic and socioeconomic data, and Rural-Urban Continuum Codes to conduct a spatial statistical analysis of community rates of breastfeeding initiation. Between 2004 and 2010, the average rate of breastfeeding initiation for Kentucky increased from 43.84% to 49.22%. Simultaneously, the number of counties identified as breastfeeding initiation hot spots also increased, displaying a systematic geographic pattern in doing so. Cool spots of breastfeeding initiation persisted in rural, Appalachian Kentucky. Spatial regression results suggested that unemployment, income, race, education, location, and the availability of International Board Certified Lactation Consultants are connected to breastfeeding initiation. Not only do spatial analytics facilitate the identification of breastfeeding initiation hot spots and cool spots, but they can be used to better understand the landscape of breastfeeding initiation and help target breastfeeding education and/or support efforts.

  8. Feasibility Study of Biopower in East Helena, Montana. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, K.

    2013-02-01

    The U.S. Environmental Protection Agency (EPA) developed the RE-Powering America's Land initiative to reuse contaminated sites for renewable energy generation when aligned with the community's vision for the site. The former American Smelting and Refining Company (Asarco) smelter in East Helena, Montana, was selected for a feasibility study under the initiative. Biomass was chosen as the renewable energy resource based on the wood products industry in the area. Biopower was selected as the technology based on Montana's renewable portfolio standard (RPS) requiring utilities to purchase renewable power.

  9. National Strategic Computing Initiative Strategic Plan

    Science.gov (United States)

    2016-07-01

    23 A.6 National Nanotechnology Initiative...program, lack the memory capacity to perform current and anticipated new classes of scientific and engineering applications, and be potentially...Initiative: https://www.nitrd.gov/nitrdgroups/index.php?title=Big_Data_(BD_SSG)  National Nanotechnology Initiative: http://www.nano.gov  Precision

  10. Combat Wound Initiative program.

    Science.gov (United States)

    Stojadinovic, Alexander; Elster, Eric; Potter, Benjamin K; Davis, Thomas A; Tadaki, Doug K; Brown, Trevor S; Ahlers, Stephen; Attinger, Christopher E; Andersen, Romney C; Burris, David; Centeno, Jose; Champion, Hunter; Crumbley, David R; Denobile, John; Duga, Michael; Dunne, James R; Eberhardt, John; Ennis, William J; Forsberg, Jonathan A; Hawksworth, Jason; Helling, Thomas S; Lazarus, Gerald S; Milner, Stephen M; Mullick, Florabel G; Owner, Christopher R; Pasquina, Paul F; Patel, Chirag R; Peoples, George E; Nissan, Aviram; Ring, Michael; Sandberg, Glenn D; Schaden, Wolfgang; Schultz, Gregory S; Scofield, Tom; Shawen, Scott B; Sheppard, Forest R; Stannard, James P; Weina, Peter J; Zenilman, Jonathan M

    2010-07-01

    The Combat Wound Initiative (CWI) program is a collaborative, multidisciplinary, and interservice public-private partnership that provides personalized, state-of-the-art, and complex wound care via targeted clinical and translational research. The CWI uses a bench-to-bedside approach to translational research, including the rapid development of a human extracorporeal shock wave therapy (ESWT) study in complex wounds after establishing the potential efficacy, biologic mechanisms, and safety of this treatment modality in a murine model. Additional clinical trials include the prospective use of clinical data, serum and wound biomarkers, and wound gene expression profiles to predict wound healing/failure and additional clinical patient outcomes following combat-related trauma. These clinical research data are analyzed using machine-based learning algorithms to develop predictive treatment models to guide clinical decision-making. Future CWI directions include additional clinical trials and study centers and the refinement and deployment of our genetically driven, personalized medicine initiative to provide patient-specific care across multiple medical disciplines, with an emphasis on combat casualty care.

  11. Student initiative: A conceptual analysis

    Directory of Open Access Journals (Sweden)

    Polovina Nada

    2014-01-01

    Full Text Available In the description and scientific consideration of the attitude of children and youth towards their education and development, the concept of student initiative has been gaining ground lately, and it is hence the subject of analysis in this paper. The analysis is important because of the discrepancy between the increased efforts of the key educational policy holders to promote the idea about the importance of the development of student initiative and rare acceptance of this idea among theoreticians, researchers and practitioners dealing with the education and development of children and youth. By concretising the features of initiative student behaviour, our aim was, on the one hand, to observe the structural determinants and scientific status of the very concept of an initiative student, and, on the other, to contribute to the understanding of the initiative behaviour in practice. In the first part of the paper we deal with different notions and concretisations of the features of initiative behaviour of children and youth, which includes the consideration of: basic student initiative, academic student initiative, individual student initiative, the capacity for initiative and personal development initiative. In the second part of the paper, we discuss the relations of the concept of student initiative with the similar general concepts (activity/passivity, proactivity, agency and the concepts immediately related to school environment (student involvement, student participation. The results of our analysis indicate that the concept of student initiative has: particular features that differentiate it from similar concepts; the potential to reach the status of a scientific concept, bearing in mind the initial empirical specifications and general empirical verifiability of the yet unverified determinants of the concept. In the concluding part of the paper, we discuss the implications of the conceptual analysis for further research, as well as for

  12. Stirling to Flight Initiative

    Science.gov (United States)

    Hibbard, Kenneth E.; Mason, Lee S.; Ndu, Obi; Smith, Clayton; Withrow, James P.

    2016-01-01

    NASA has a consistent need for radioisotope power systems (RPS) to enable robotic scientific missions for planetary exploration that has been present for over four decades and will continue into the foreseeable future, as documented in the most recent Planetary Science Decadal Study Report. As RPS have evolved throughout the years, there has also grown a desire for more efficient power systems, allowing NASA to serve as good stewards of the limited plutonium-238 (238Pu), while also supporting the ever-present need to minimize mass and potential impacts to the desired science measurements. In fact, the recent Nuclear Power Assessment Study (NPAS) released in April 2015 resulted in several key conclusion regarding RPS, including affirmation that RPS will be necessary well into the 2030s (at least) and that 238Pu is indeed a precious resource requiring efficient utilization and preservation. Stirling Radioisotope Generators (SRGs) combine a Stirling cycle engine powered by a radioisotope heater unit into a single generator system. Stirling engine technology has been under development at NASA Glenn Research Center (GRC) in partnership with the Department of Energy (DOE) since the 1970's. The most recent design, the 238Pu-fueled Advanced Stirling Radioisotope Generator (ASRG), was offered as part of the NASA Discovery 2010 Announcement of Opportunity (AO). The Step-2 selections for this AO included two ASRG-enabled concepts, the Titan Mare Explorer (TiME) and the Comet Hopper (CHopper), although the only non-nuclear concept, InSight, was ultimately chosen. The DOE's ASRG contract was terminated in 2013. Given that SRGs utilize significantly less 238Pu than traditional Radioisotope Thermoelectric Generators (RTGs) - approximately one quarter of the nuclear fuel, to produce similar electrical power output - they provide a technology worthy of consideration for meeting the aforementioned NASA objectives. NASA's RPS Program Office has recently investigated a new Stirling to

  13. Initialized Fractional Calculus

    Science.gov (United States)

    Lorenzo, Carl F.; Hartley, Tom T.

    2000-01-01

    This paper demonstrates the need for a nonconstant initialization for the fractional calculus and establishes a basic definition set for the initialized fractional differintegral. This definition set allows the formalization of an initialized fractional calculus. Two basis calculi are considered; the Riemann-Liouville and the Grunwald fractional calculi. Two forms of initialization, terminal and side are developed.

  14. An economic analysis of a major bio-fuel program undertaken by OECD countries

    International Nuclear Information System (INIS)

    2002-01-01

    Biofuels such as ethanol and bio-diesel are creating a new demand for agricultural output and for agriculture land in Canada. However, the participation of other large countries with a large demand potential is necessary for bio-fuels to have a significant impact on the price of grains and oilseeds. This paper quantified the potential impact that a major bio-fuel program initiated by OECD countries has on grain and oilseed prices. The program was initiated for the period 1999 to 2006. There is considerable interest by Canadian producers to stimulate grain and oilseed prices by increasing demand of biofuels. This renewable energy source produces fewer greenhouse gas emissions than petroleum products. The analysis presented in this paper only considered ethanol from corn or wheat and bio-diesel from vegetable oils. It also focused only on the use of bio-fuels in the OECD transportation sector. The analysis was undertaken with AGLINK, a multi-commodity multi-country policy-specific dynamic model of the international agricultural markets built by the OECD with member countries. It was shown that the increase in world and domestic prices for grains and vegetable oils will remain strong, particularly toward 2006. It was also shown that a major bio-fuel program for all OECD countries would be beneficial to Canadian agriculture. It was concluded that ultimately, an increase in OECD bio-fuels usage has a direct impact on the demand for grains and oilseeds which are important feed-stocks in biofuel production. The analysis presumes an increase in renewable fuel use, but does not consider factors such as financial incentives and regulatory requirements that could bring about this increase. 7 refs., 6 tabs., 4 figs

  15. Optimization of Jatropha curcas pure plant oil production

    NARCIS (Netherlands)

    Subroto, Erna

    2015-01-01

    The use of pure plant oils as fuel, either directly or after conversion of the oil to bio-diesel, is considered to be one of the potential contributions to the transformation of the current fossil oil based economy to a sustainable bio-based one. The production of oil producing seeds using plants

  16. Dioxin Exposure Initiative

    Science.gov (United States)

    The Dioxin Exposure Initiative (DEI) is no longer active. This page contains a summary of the dioxin exposure initiative with illustrations, contact and background information.Originally supported by scientist Matthew Lorber, who retired in Mar 2017.

  17. Initial Cladding Condition

    International Nuclear Information System (INIS)

    Siegmann, E.

    2000-01-01

    The purpose of this analysis is to describe the condition of commercial Zircaloy clad fuel as it is received at the Yucca Mountain Project (YMP) site. Most commercial nuclear fuel is encased in Zircaloy cladding. This analysis is developed to describe cladding degradation from the expected failure modes. This includes reactor operation impacts including incipient failures, potential degradation after reactor operation during spent fuel storage in pool and dry storage and impacts due to transportation. Degradation modes include cladding creep, and delayed hydride cracking during dry storage and transportation. Mechanical stresses from fuel handling and transportation vibrations are also included. This Analysis and Model Report (AMR) does not address any potential damage to assemblies that might occur at the YMP surface facilities. Ranges and uncertainties have been defined. This analysis will be the initial boundary condition for the analysis of cladding degradation inside the repository. In accordance with AP-2.13Q, ''Technical Product Development Planning'', a work plan (CRWMS M andO 2000c) was developed, issued, and utilized in the preparation of this document. There are constraints, caveats and limitations to this analysis. This cladding degradation analysis is based on commercial Pressurized Water Reactor (PWR) fuel with Zircaloy cladding but is applicable to Boiling Water Reactor (BWR) fuel. Reactor operating experience for both PWRs and BWRs is used to establish fuel reliability from reactor operation. It is limited to fuel exposed to normal operation and anticipated operational occurrences (i.e. events which are anticipated to occur within a reactor lifetime), and not to fuel that has been exposed to severe accidents. Fuel burnup projections have been limited to the current commercial reactor licensing environment with restrictions on fuel enrichment, oxide coating thickness and rod plenum pressures. The information provided in this analysis will be used in

  18. Feasibility Study of Economics and Performance of a Hydroelectric Installation at the Jeddo Mine Drainage Tunnel. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, J. O.; Mosey, G.

    2013-02-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Jeddo Tunnel discharge site for a feasibility study of renewable energy potential. The purpose of this report is to assess technical and economic viability of the site for hydroelectric and geothermal energy production. In addition, the report outlines financing options that could assist in the implementation of a system.

  19. Tall Buildings Initiative

    Science.gov (United States)

    Initiative 2017 TBI Guidelines Version 2.03 Now Available Screen Shot 2017-10-10 at 3.05.10 PM PEER has just initiative to develop design criteria that will ensure safe and usable tall buildings following future earthquakes. Download the primary product of this initiative: Guidelines for Performance-Based Seismic Design

  20. Concepções de conhecimento escolar: potencialidades do Programa Institucional de Bolsa de Iniciação à Docência Concepts of school knowledge: potentialities of the Institutional Program of Teaching Initiation Scholarships

    Directory of Open Access Journals (Sweden)

    Andréa Rosana Fetzner

    2012-09-01

    Full Text Available Considerando-se as possibilidades abertas por meio do Programa Institucional de Bolsa de Iniciação à Docência (PIBID, o presente artigo discute as concepções de conhecimento escolar e os desafios de um projeto de transformação da escola básica em uma instituição que assuma perspectivas interculturais em relação ao conhecimento escolar. Nesse sentido, compreende-se que ainda é um desafio, para muitas escolas de ensino fundamental, reconhecer e trabalhar com conhecimentos que sejam significativos para a população que as frequenta. Apoiado pela CAPES, no âmbito do PIBID, este trabalho apresenta os resultados iniciais de um estudo sobre as concepções de conhecimento escolar que permeiam os saberes da docência de professores de escolas públicas e de bolsistas de iniciação à docência envolvidos no projeto. O desenvolvimento da pesquisa deu-se mediante o estudo da interculturalidade e de seus desafios contemporâneos, o acompanhamento do trabalho desenvolvido nas escolas e a aplicação de questionários a estudantes bolsistas de iniciação à docência da Universidade Federal do Estado do Rio de Janeiro (UNIRIO, que desenvolvem um projeto por meio do referido programa. Observamos, até o presente momento, que a concepção de conhecimento escolar tem oscilado entre perspectivas conservadoras e perspectivas emancipatórias, sendo estas últimas entendidas como aquelas que, compartilhando do conceito de bem viver, procuram integrar-se às necessidades das comunidades e compartilhar de princípios que envolvem a relacionalidade, a correspondência e a complementariedade, tal como salienta Catherine Walsh.Considering the possibilities resulting from the Institutional Program of Teaching Initiation Scholarships (PIBID, this paper discusses the concepts of school knowledge and the challenges of project to transform basic schooling into an institution that takes intercultural perspectives in relation to school knowledge. Thus, it is

  1. Guam Initial Technical Assessment Report

    Energy Technology Data Exchange (ETDEWEB)

    Baring-Gould, I.; Conrad, M.; Haase, S.; Hotchkiss, E.; McNutt, P.

    2011-04-01

    Under an interagency agreement, funded by the Department of Interior's (DOI) Office of Insular Affairs (OIA), the National Renewable Energy Laboratory (NREL) was tasked to deliver technical assistance to the island of Guam by conducting an island initial technical assessment that would lay out energy consumption and production data and establish a baseline. This assessment will be used to conduct future analysis and studies by NREL that will estimate energy efficiency and renewable energy potential for the island of Guam.

  2. CubeSat Launch Initiative

    Science.gov (United States)

    Higginbotham, Scott

    2016-01-01

    The National Aeronautics and Space Administration (NASA) recognizes the tremendous potential that CubeSats (very small satellites) have to inexpensively demonstrate advanced technologies, collect scientific data, and enhance student engagement in Science, Technology, Engineering, and Mathematics (STEM). The CubeSat Launch Initiative (CSLI) was created to provide launch opportunities for CubeSats developed by academic institutions, non-profit entities, and NASA centers. This presentation will provide an overview of the CSLI, its benefits, and its results.

  3. MONTANA PALLADIUM RESEARCH INITIATIVE

    Energy Technology Data Exchange (ETDEWEB)

    Peters, John; McCloskey, Jay; Douglas, Trevor; Young, Mark; Snyder, Stuart; Gurney, Brian

    2012-05-09

    Project Objective: The overarching objective of the Montana Palladium Research Initiative is to perform scientific research on the properties and uses of palladium in the context of the U.S. Department of Energy's Hydrogen, Fuel Cells and Infrastructure Technologies Program. The purpose of the research will be to explore possible palladium as an alternative to platinum in hydrogen-economy applications. To achieve this objective, the Initiatives activities will focus on several cutting-edge research approaches across a range of disciplines, including metallurgy, biomimetics, instrumentation development, and systems analysis. Background: Platinum-group elements (PGEs) play significant roles in processing hydrogen, an element that shows high potential to address this need in the U.S. and the world for inexpensive, reliable, clean energy. Platinum, however, is a very expensive component of current and planned systems, so less-expensive alternatives that have similar physical properties are being sought. To this end, several tasks have been defined under the rubric of the Montana Palladium Research Iniative. This broad swath of activities will allow progress on several fronts. The membrane-related activities of Task 1 employs state-of-the-art and leading-edge technologies to develop new, ceramic-substrate metallic membranes for the production of high-purity hydrogen, and develop techniques for the production of thin, defect-free platinum group element catalytic membranes for energy production and pollution control. The biomimetic work in Task 2 explores the use of substrate-attached hydrogen-producing enzymes and the encapsulation of palladium in virion-based protein coats to determine their utility for distributed hydrogen production. Task 3 work involves developing laser-induced breakdown spectroscopy (LIBS) as a real-time, in situ diagnostic technique to characterize PGEs nanoparticles for process monitoring and control. The systems engineering work in task 4

  4. Integrated Initiating Event Performance Indicators

    International Nuclear Information System (INIS)

    S. A. Eide; Dale M. Rasmuson; Corwin L. Atwood

    2005-01-01

    The U.S. Nuclear Regulatory Commission Industry Trends Program (ITP) collects and analyses industry-wide data, assesses the safety significance of results, and communicates results to Congress and other stakeholders. This paper outlines potential enhancements in the ITP to comprehensively cover the Initiating Events Cornerstone of Safety. Future work will address other cornerstones of safety. The proposed Tier 1 activity involves collecting data on ten categories of risk-significant initiating events, trending the results, and comparing early performance with prediction limits (allowable numbers of events, above which NRC action may occur). Tier 1 results would be used to monitor industry performance at the level of individual categories of initiating events. The proposed Tier 2 activity involves integrating the information for individual categories of initiating events into a single risk-based indicator, termed the Baseline Risk Index for Initiating Events or BRIIE. The BRIIE would be evaluated yearly and compared against a threshold. BRIIE results would be reported to Congress on a yearly basis

  5. Potencial alelopático de espécies nativas na germinação e crescimento inicial de Lactuca sativa L. (Asteraceae Allelopathic potential of native species in Lactuca sativa L. (Asteraceae germination and initial growth

    Directory of Open Access Journals (Sweden)

    Fabiana Maraschin-Silva

    2006-03-01

    Full Text Available A alelopatia caracteriza-se pelos efeitos danosos ou benéficos sobre o desenvolvimento da vegetação, causados por substâncias químicas produzidas e liberadas para o ambiente por uma planta. Com o objetivo de avaliar o potencial alelopático de espécies brasileiras, foram testados extratos foliares de Cecropia pachystachya Trec. (Urticaceae, Peltophorum dubium (Spreng. Taub. (Fabaceae, Psychotria leiocarpa Cham. & Schltdl (Rubiaceae, Sapium glandulatum (Vell. Pax (Euphorbiaceae e Sorocea bonplandii (Baill. Burg., Lanj. & Boer (Moraceae, utilizando-se bioensaios de germinação e crescimento e alface (Lactuca sativa L. como planta alvo. Nesses bioensaios, foram usados extratos foliares aquosos nas concentrações de 2 e 4%, preparados por maceração estática com água fria e quente. Os extratos das cinco espécies causaram atraso na germinação dos aquênios da alface, bem como efeitos tóxicos no crescimento das plântulas, com redução e enfraquecimento das raízes. Os resultados obtidos mostraram a presença de substâncias químicas inibidoras nos extratos, revelando potencial alelopático para as cinco espécies avaliadas.Allelopathy is characterized by harmful or beneficial effects on vegetation development, caused by chemical substances produced and released into the environment by the plant. Aiming to assess the allelopathic potential of Brazilian species, aqueous leaf extracts of Cecropia pachystachya Trec. (Urticaceae, Peltophorum dubium (Spreng. Taub. (Fabaceae, Psychotria leiocarpa Cham. & Schltdl (Rubiaceae, Sapium glandulatum (Vell. Pax (Euphorbiaceae, and Sorocea bonplandii (Baill. Burger, Lanj. & Boer (Moraceae were tested on lettuce using germination and growth bioassays. In these bioassays, aqueous leaf extracts were used at concentrations of 2 and 4%, prepared by static maceration with cold and hot water. The five species extracts delayed lettuce germination and produced toxic effects on seedling growth, with root

  6. Targeted Radiation Therapy for Cancer Initiative

    Science.gov (United States)

    2017-11-01

    AWARD NUMBER: W81XWH-08-2-0174 TITLE: Targeted Radiation Therapy for Cancer Initiative PRINCIPAL INVESTIGATOR: Dusten Macdonald, MD...for Cancer Initiative 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Dusten Macdonald, MD 5d. PROJECT NUMBER...Cancer Initiative Final Report INTRODUCTION: The full potential of radiation therapy has not been realized due to the inability to locate and

  7. A comparative study on the effect of unsaturation degree of camelina and canola oils on the optimization of bio-diesel production

    Directory of Open Access Journals (Sweden)

    Jie Yang

    2016-11-01

    Full Text Available Transesterification is the most common method of producing biodiesel from vegetable oils. A comparative study on the optimization of reaction variables for refined canola oil, unrefined canola oil, and unrefined camelina oil using a four-factor (temperature, time, molar ratio of methanol to oil, and catalyst loading face-centered central composite design (FCCCD was carried out. The optimum settings of these four factors that jointly maximize product, fatty acid methyl ester (FAME and biodiesel yields for each of refined canola, unrefined canola and unrefined camelina were determined. Results showed that the optimized conditions were associated with the fatty acid profile and physical properties of the parent oils. The optimum temperature of vegetable oil with low polyunsaturation degree was higher than that of oils with high polyunsaturation degree. High free fatty acid content in parent oils led to low optimized catalyst concentration, and the decreased reaction rate could be compensated by increased reaction temperature due to significant interaction effect between reaction temperature and catalyst loading in the transesterification process. The highest biodiesel yields from the optimum setting for refined canola oil, unrefined canola oil, and unrefined camelina oil were 97.7%, 95.2%, and 95.6%, respectively. This study provided guidelines on how to optimize different reaction variables taking economic viability and feedstock availability into consideration when producing biodiesel at plant scale.

  8. Biological inflammatory and metabolic effects of petro- and bio-diesel exhaust particulate matter emissions from a light-duty diesel engine.

    Science.gov (United States)

    2015-06-01

    Sustainability of our transportation system depends on making well-informed choices on : vehicle energy sources for human and goods mobility. Motor vehicles operating on fossil : fuels are a significant source of air pollution risk and challenge the ...

  9. Energetic analysis of experimental process in bio diesel production from chicken oil; Analise energetica do proceso experimental de producao de biodiesel a partir de oleo de frango

    Energy Technology Data Exchange (ETDEWEB)

    Bonometo, Ricardo Pacheco [Universidade Estadual Paulista (FCA/UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas. Programa de Pos-Graduacao em Energia na Agricultura], E-mail: rpbonometo@yahoo.com.br; Justi, Andre Luiz [Universidade Estadual Paulista (FCA/UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas. Programa de Pos-Graduacao em Irrigacao e Drenagem], E-mail: aljusti@fca.unesp.br; Buchi, Alisson Teixeira [Universidade Estadual Paulista (CEVAP/UNESP), Botucatu, SP (Brazil). Centro de Estudos de Venenos e Animais Peconhentos], E-mail: atbuchi@yahoo.com.br; Saglietti, Jose Roberto [Universidade Estadual Paulista (FCA/UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas. Dept. de Fisica e Biofisica], E-mail: jroberto@ibb.unesp.br

    2010-07-01

    There is a great global concern about the depletion and the high cost of fossil fuel reserves exploitation, more than ever, it is necessary to make a profound study and take advantage of alternative sources that can be used as energy efficiency with an appropriate pricing and low environmental impact. Brazil, which has highlighted using alternative energy sources as the use of ethanol and, in recent years, has been encouraging the expansion of its energy matrix in which the biodiesel will have a strategic importance within the agrobusiness area. Biodiesel is a fuel that can replace the diesel, which is a petroleum derivative. It is an ester, produced in the transesterification reaction of vegetable oils and animal greases, in an alcohol with an additional catalyst, are converted into fatty acids and result in esters with glycerol as sub products. The objective of this study was to estimate the final energy balance for the process biodiesel production from oil chicken waste. The energy balance estimation was quantified in calorific value according to the energy expenditure by calorimetric bomb method. The relationship between input and output of energy was around 0.97. In a first evaluation, the procedures adopted should be improved enough, so the process can become energetic and economically viable. (author)

  10. Tailpipe emissions and engine performance of a light-duty diesel engine operating on petro- and bio-diesel fuel blends.

    Science.gov (United States)

    2014-06-01

    This report summarizes the experimental apparatus developed in the Transportation Air Quality Laboratory (TAQ Lab) at the University of Vermont to compare light-duty diesel engine performance and exhaust emissions when operating on petroleum diesel (...

  11. Non-invasive rapid harvest time determination of oil-producing microalgae cultivations for bio-diesel production by using Chlorophyll fluorescence

    Directory of Open Access Journals (Sweden)

    Yaqin eQiao

    2015-10-01

    Full Text Available For the large-scale cultivation of microalgae for biodiesel production, one of the key problems is the determination of the optimum time for algal harvest when algae cells are saturated with neutral lipids. In this study, a method to determine the optimum harvest time in oil-producing microalgal cultivations by measuring the maximum photochemical efficiency of photosystem II (PSII, also called Fv/Fm, was established. When oil-producing Chlorella strains were cultivated and then treated with nitrogen starvation, it not only stimulated neutral lipid accumulation, but also affected the photosynthesis system, with the neutral lipid contents in all four algae strains – Chlorella sorokiniana C1, Chlorella sp. C2, C. sorokiniana C3, C. sorokiniana C7 – correlating negatively with the Fv/Fm values. Thus, for the given oil-producing algae, in which a significant relationship between the neutral lipid content and Fv/Fm value under nutrient stress can be established, the optimum harvest time can be determined by measuring the value of Fv/Fm. It is hoped that this method can provide an efficient way to determine the harvest time rapidly and expediently in large-scale oil-producing microalgae cultivations for biodiesel production.

  12. Metaloxide--ZrO2 catalysts for the esterification and transesterification of free fatty acids and triglycerides to obtain bio-diesel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Manhoe; Salley, Steven O.; Ng, K. Y. Simon

    2016-09-06

    Mixed metal oxide catalysts (ZnO, CeO, La2O3, NiO, Al203, SiO2, TiO2, Nd2O3, Yb2O3, or any combination of these) supported on zirconia (ZrO2) or hydrous zirconia are provided. These mixed metal oxide catalysts can be prepared via coprecipitation, impregnation, or sol-gel methods from metal salt precursors with/without a Zirconium salt precursor. Metal oxides/ZrO2 catalyzes both esterification and transesterification of oil containing free fatty acids in one batch or in single stage. In particular, these mixed metal oxides supported or added on zirconium oxide exhibit good activity and selectivity for esterification and transesterification. The low acid strength of this catalyst can avoid undesirable side reaction such as alcohol dehydration or cracking of fatty acids. Metal oxides/ZrO2 catalysts are not sensitive to any water generated from esterification. Thus, esterification does not require a water free condition or the presence of excess methanol to occur when using the mixed metal oxide catalyst. The FAME yield obtained with metal oxides/ZrO2 is higher than that obtained with homogeneous sulfuric acid catalyst. Metal oxides/ZrO2 catalasts can be prepared as strong pellets and in various shapes for use directly in a flow reactor. Furthermore, the pellet has a strong resistance toward dissolution to aqueous or oil phases.

  13. Socio environmental approach of production of bio diesel in the Energy Decenal Plan 2008 - 2017; Abordagem socioambiental da producao de biodiesel no Plano Decenal de Energia 2008 - 2017

    Energy Technology Data Exchange (ETDEWEB)

    Conde, Marcos; Almeida, Andre; Silva, Cesar; Botelho, Glauce; Vieira, Hermani; Nuti, Mirian; Furtado, Ricardo [Secretaria do Meio Ambiente do Estado de Sao Paulo (SMA/EPE), SP (Brazil). Escola de Politicas de Estado

    2008-07-01

    This article presents the brief exposition of the central points of the associated studies to the PDE 2008-2017, as far the biodiesel is concerning. These exposition viewed the identification of socioenvironmental variable of the productive chain of the biodiesel, not only production facilities but also the agricultural phase and the benefits of residual greasy input, focusing through 'input', 'residues' and 'social perspectives' categories. It is expected that the studies presented in this paper can constituted adequate subsides for the development of the methodology during the next planning cycles.

  14. Emerging Pathogens Initiative (EPI)

    Data.gov (United States)

    Department of Veterans Affairs — The Emerging Pathogens Initiative (EPI) database contains emerging pathogens information from the local Veterans Affairs Medical Centers (VAMCs). The EPI software...

  15. Hazardous material reduction initiative

    International Nuclear Information System (INIS)

    Nichols, D.H.

    1995-02-01

    The Hazardous Material Reduction Initiative (HMRI) explores using the review of purchase requisitions to reduce both the use of hazardous materials and the generation of regulated and nonregulated wastes. Based on an 11-month program implemented at the Hanford Site, hazardous material use and waste generation was effectively reduced by using a centralized procurement control program known as HMRI. As expected, several changes to the original proposal were needed during the development/testing phase of the program to accommodate changing and actual conditions found at the Hanford Site. The current method requires a central receiving point within the Procurement Organization to review all purchase requisitions for potentially Occupational Safety and Health Administration (OSHA) hazardous products. Those requisitions (approximately 4% to 6% of the total) are then forwarded to Pollution Prevention personnel for evaluation under HMRI. The first step is to determine if the requested item can be filled by existing or surplus material. The requisitions that cannot filled by existing or surplus material are then sorted into two groups based on applicability to the HMRI project. For example, laboratory requests for analytical reagents or standards are excluded and the purchase requisitions are returned to Procurement for normal processing because, although regulated, there is little opportunity for source reduction due to the strict protocols followed. Each item is then checked to determine if it is regulated or not. Regulated items are prioritized based on hazardous contents, quantity requested, and end use. Copies of these requisitions are made and the originals are returned to Procurement within 1-hr. Since changes to the requisition can be made at later stages during procurement, the HMRI fulfills one of its original premises in that it does not slow the procurement process

  16. Diagnostic potential of PET/CT using a {sup 68}Ga-labelled prostate-specific membrane antigen ligand in whole-body staging of renal cell carcinoma: initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Sawicki, Lino M.; Buchbender, Christian; Boos, Johannes; Antoch, Gerald [University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Dusseldorf (Germany); Giessing, Markus [University Dusseldorf, Medical Faculty, Department of Urology, Dusseldorf (Germany); Ermert, Johannes [Juelich Research Center, Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Juelich (Germany); Antke, Christina; Hautzel, Hubertus [University Dusseldorf, Medical Faculty, Department of Nuclear Medicine, Dusseldorf (Germany)

    2017-01-15

    To evaluate the diagnostic potential of whole-body PET/CT using a {sup 68}Ga-labelled PSMA ligand in renal cell carcinoma (RCC). Six patients with histopathologically proven RCC underwent {sup 68}Ga-PSMA PET/CT. Each PET/CT scan was evaluated in relation to lesion count, location and dignity. SUVmax was measured in primary tumours and PET-positive metastases. Tumour-to-background SUVmax ratios (TBR{sub SUVmax}) were calculated for primary RCCs in relation to the surrounding normal renal parenchyma. Metastasis-to-background SUVmax ratios (MBR{sub SUVmax}) were calculated for PET-positive metastases in relation to gluteal muscle. Five primary RCCs and 16 metastases were evaluated. The mean SUVmax of the primary RCCs was 9.9 ± 9.2 (range 1.7 - 27.2). Due to high uptake in the surrounding renal parenchyma, the mean TBR{sub SUVmax} of the primary RCCs was only 0.2 ± 0.3 (range 0.02 - 0.7). Eight metastases showed focal {sup 68}Ga-PSMA uptake (SUVmax 9.9 ± 8.3, range 3.4 - 25.6). The mean MBR{sub SUVmax} of these PET-positive metastases was 11.7 ± 0.2 (range 4.4 - 28.1). All PET-negative metastases were subcentimetre lung metastases. {sup 68}Ga-PSMA PET/CT appears to be a promising method for detecting RCC metastases. However, no additional diagnostic value in assessing the primary tumour was found. (orig.)

  17. Synthesis of two potential NK1-receptor ligands using [1-11C]ethyl iodide and [1-11C]propyl iodide and initial PET-imaging

    Directory of Open Access Journals (Sweden)

    Genchel Tove

    2007-07-01

    Full Text Available Abstract Background The previously validated NK1-receptor ligand [O-methyl-11C]GR205171 binds with a high affinity to the NK1-receptor and displays a slow dissociation from the receptor. Hence, it cannot be used in vivo for detecting concentration changes in substance P, the endogenous ligand for the NK1-receptor. A radioligand used for monitoring these changes has to enable displacement by the endogenous ligand and thus bind reversibly to the receptor. Small changes in the structure of a receptor ligand can lead to changes in binding characteristics and also in the ability to penetrate the blood-brain barrier. The aim of this study was to use carbon-11 labelled ethyl and propyl iodide with high specific radioactivity in the synthesis of two new and potentially reversible NK1-receptor ligands with chemical structures based on [O-methyl-11C]GR205171. Methods [1-11C]Ethyl and [1-11C]propyl iodide with specific radioactivities of 90 GBq/μmol and 270 GBq/μmol, respectively, were used in the synthesis of [O-methyl-11C]GR205171 analogues by alkylation of O-desmethyl GR205171. The brain uptake of the obtained (2S,3S-N-(1-(2- [1-11C]ethoxy-5-(3-(trifluoromethyl-4H-1,2,4-triazol-4-ylphenylethyl-2-phenylpiperidin-3-amine (I and (2S,3S-2-phenyl-N-(1-(2- [1-11C]propoxy-5-(3-(trifluoromethyl-4H-1,2,4-triazol-4-ylphenylethylpiperidin-3-amine (II was studied with PET in guinea pigs and rhesus monkeys and compared to the uptake of [O-methyl-11C]GR205171. Results All ligands had similar uptake distribution in the guinea pig brain. The PET-studies in rhesus monkeys showed that (II had no specific binding in striatum. Ligand (I had moderate specific binding compared to the [O-methyl-11C]GR205171. The ethyl analogue (I displayed reversible binding characteristics contrary to the slow dissociation rate shown by [O-methyl-11C]GR205171. Conclusion The propyl-analogue (II cannot be used for detecting changes in NK1-ligand levels, while further studies should be

  18. AC Initiation System.

    Science.gov (United States)

    An ac initiation system is described which uses three ac transmission signals interlocked for safety by frequency, phase, and power discrimination...The ac initiation system is pre-armed by the application of two ac signals have the proper phases, and activates a load when an ac power signal of the proper frequency and power level is applied. (Author)

  19. Sustainable Agricultural Marketing Initiatives

    Directory of Open Access Journals (Sweden)

    Hakan Adanacıoğlu

    2015-07-01

    Full Text Available Sustainable marketing is a holistic approach that puts equal emphasis on environmental, social equity, and economic concerns in the development of marketing strategies. The purpose of the study is to examine and discuss the sustainable agricultural marketing initiatives practiced throughout the World and Turkey, and to put forth suggestions to further improve the performance of agricultural marketing initiatives in Turkey. Some of the sustainable agricultural marketing initiatives practiced around the world are carried out through civil organizations. Furthermore; some of these initiatives have also launched by farmers, consumers, food processors and retailers. The long-term strategies to increase these initiatives should be determined due to the fact that examples of successful sustainable agricultural marketing initiatives are inadequate and cannot be spread in Turkey. In this context, first of all, the supports provided by the government to improve agricultural marketing systems, such as EU funds for rural development should be compatible with the goals of sustainable marketing. For this purpose, it should be examined whether all proposed projects related to agricultural marketing meet the social, economic, and environmental principles of sustainable marketing. It is important that supporting organizations, especially civil society organisations, should take an active role for faster dissemination and adoption of sustainable agricultural marketing practices in Turkey. These organizations may provide technical assistance in preparing successful project proposals and training to farm groups. In addition, the other organizations, such as local administrations, producers' associations, cooperatives, can contribute to the success of sustainable agricultural marketing initiatives. The use of direct marketing strategies and vertical integration attempts in sustainable agricultural marketing initiatives that will likely be implemented in Turkey is

  20. NAMA 80/20 DEFERRED PAYMENT INITIATIVE PARTICIPATION FORM

    OpenAIRE

    2012-01-01

    Brochure detailing the Deferred Payment Initiative key features and information on how to apply for the initiative: "NAMA has launched a Deferred Payment Initiative (the ‘Initiative’) on a pilot basis. The Initiative is aimed at potential owner-occupiers who are interested in purchasing residential property but are concerned at the risk of further price declines."

  1. 1996 environmental initiatives report

    International Nuclear Information System (INIS)

    1996-01-01

    Progress by Consumers Gas in addressing environmental challenges were reviewed. Proposed environmental initiatives for the next fiscal year and beyond were introduced. Proposed initiatives were placed into three priority categories, high, medium or low, which together with the environmental management framework form the the utility's overall environmental agenda. High on the list of environmental priorities for the company are atmospheric air emissions, planning and construction practices, energy conservation and efficiency, environmental compliance, and methane emissions. The present state of the initiatives by the various company divisions and regions, compiled from the respective business plans, were reported. 21 figs

  2. Extraction of medium chain fatty acids from organic municipal waste and subsequent production of bio-based fuels.

    Science.gov (United States)

    Kannengiesser, Jan; Sakaguchi-Söder, Kaori; Mrukwia, Timo; Jager, Johannes; Schebek, Liselotte

    2016-01-01

    This paper provides an overview on investigations for a new technology to generate bio-based fuel additives from bio-waste. The investigations are taking place at the composting plant in Darmstadt-Kranichstein (Germany). The aim is to explore the potential of bio-waste as feedstock in producing different bio-based products (or bio-based fuels). For this investigation, a facultative anaerobic process is to be integrated into the normal aerobic waste treatment process for composting. The bio-waste is to be treated in four steps to produce biofuels. The first step is the facultative anaerobic treatment of the waste in a rotting box namely percolate to generate a fatty-acid rich liquid fraction. The Hydrolysis takes place in the rotting box during the waste treatment. The organic compounds are then dissolved and transferred into the waste liquid phase. Browne et al. (2013) describes the hydrolysis as an enzymatically degradation of high solid substrates to soluble products which are further degraded to volatile fatty acids (VFA). This is confirmed by analytical tests done on the liquid fraction. After the percolation, volatile and medium chain fatty acids are found in the liquid phase. Concentrations of fatty acids between 8.0 and 31.5 were detected depending on the nature of the input material. In the second step, a fermentation process will be initiated to produce additional fatty acids. Existing microorganism mass is activated to degrade the organic components that are still remaining in the percolate. After fermentation the quantity of fatty acids in four investigated reactors increased 3-5 times. While fermentation mainly non-polar fatty acids (pentanoic to octanoic acid) are build. Next to the fermentation process, a chain-elongation step is arranged by adding ethanol to the fatty acid rich percolate. While these investigations a chain-elongation of mainly fatty acids with pair numbers of carbon atoms (acetate, butanoic and hexanoic acid) are demonstrated. After

  3. The national geomagnetic initiative

    Science.gov (United States)

    1993-01-01

    The Earth's magnetic field, through its variability over a spectrum of spatial and temporal scales, contains fundamental information on the solid Earth and geospace environment (the latter comprising the atmosphere, ionosphere, and magnetosphere). Integrated studies of the geomagnetic field have the potential to address a wide range of important processes in the deep mantle and core, asthenosphere, lithosphere, oceans, and the solar-terrestrial environment. These studies have direct applications to important societal problems, including resource assessment and exploration, natural hazard mitigation, safe navigation, and the maintenance and survivability of communications and power systems on the ground and in space. Studies of the Earth's magnetic field are supported by a variety of federal and state agencies as well as by private industry. Both basic and applied research is presently supported by several federal agencies, including the National Science Foundation (NSF), U.S. Geological Survey (USGS), U.S. Department of Energy (DOE), National Oceanic and Atmospheric Administration (NOAA), National Aeronautics and Space Administration (NASA), and U.S. Department of Defense (DOD) (through the Navy, Air Force, and Defense Mapping Agency). Although each agency has a unique, well-defined mission in geomagnetic studies, many areas of interest overlap. For example, NASA, the Navy, and USGS collaborate closely in the development of main field reference models. NASA, NSF, and the Air Force collaborate in space physics. These interagency linkages need to be strengthened. Over the past decade, new opportunities for fundamental advances in geomagnetic research have emerged as a result of three factors: well-posed, first-order scientific questions; increased interrelation of research activities dealing with geomagnetic phenomena; and recent developments in technology. These new opportunities can be exploited through a national geomagnetic initiative to define objectives and

  4. Initial Radionuclide Inventories

    Energy Technology Data Exchange (ETDEWEB)

    H. Miller

    2004-09-19

    The purpose of this analysis is to provide an initial radionuclide inventory (in grams per waste package) and associated uncertainty distributions for use in the Total System Performance Assessment for the License Application (TSPA-LA) in support of the license application for the repository at Yucca Mountain, Nevada. This document is intended for use in postclosure analysis only. Bounding waste stream information and data were collected that capture probable limits. For commercially generated waste, this analysis considers alternative waste stream projections to bound the characteristics of wastes likely to be encountered using arrival scenarios that potentially impact the commercial spent nuclear fuel (CSNF) waste stream. For TSPA-LA, this radionuclide inventory analysis considers U.S. Department of Energy (DOE) high-level radioactive waste (DHLW) glass and two types of spent nuclear fuel (SNF): CSNF and DOE-owned (DSNF). These wastes are placed in two groups of waste packages: the CSNF waste package and the codisposal waste package (CDSP), which are designated to contain DHLW glass and DSNF, or DHLW glass only. The radionuclide inventory for naval SNF is provided separately in the classified ''Naval Nuclear Propulsion Program Technical Support Document'' for the License Application. As noted previously, the radionuclide inventory data presented here is intended only for TSPA-LA postclosure calculations. It is not applicable to preclosure safety calculations. Safe storage, transportation, and ultimate disposal of these wastes require safety analyses to support the design and licensing of repository equipment and facilities. These analyses will require radionuclide inventories to represent the radioactive source term that must be accommodated during handling, storage and disposition of these wastes. This analysis uses the best available information to identify the radionuclide inventory that is expected at the last year of last emplacement

  5. Research Programs & Initiatives

    Science.gov (United States)

    CGH develops international initiatives and collaborates with other NCI divisions, NCI-designated Cancer Centers, and other countries to support cancer control planning, encourage capacity building, and support cancer research and research networks.

  6. Nursing Home Quality Initiative

    Data.gov (United States)

    U.S. Department of Health & Human Services — This Nursing Home Quality Initiative (NHQI) website provides consumer and provider information regarding the quality of care in nursing homes. NHQI discusses quality...

  7. Surgical Critical Care Initiative

    Data.gov (United States)

    Federal Laboratory Consortium — The Surgical Critical Care Initiative (SC2i) is a USU research program established in October 2013 to develop, translate, and validate biology-driven critical care....

  8. Global Methane Initiative

    Science.gov (United States)

    The Global Methane Initiative promotes cost-effective, near-term methane recovery through partnerships between developed and developing countries, with participation from the private sector, development banks, and nongovernmental organizations.

  9. Medical Errors Reduction Initiative

    National Research Council Canada - National Science Library

    Mutter, Michael L

    2005-01-01

    The Valley Hospital of Ridgewood, New Jersey, is proposing to extend a limited but highly successful specimen management and medication administration medical errors reduction initiative on a hospital-wide basis...

  10. RAS Initiative - Community Outreach

    Science.gov (United States)

    Through community and technical collaborations, workshops and symposia, and the distribution of reference reagents, the RAS Initiative seeks to increase the sharing of knowledge and resources essential to defeating cancers caused by mutant RAS genes.

  11. RAS Initiative - Events

    Science.gov (United States)

    The NCI RAS Initiative has organized multiple events with outside experts to discuss how the latest scientific and technological breakthroughs can be applied to discover vulnerabilities in RAS-driven cancers.

  12. PESP Landscaping Initiative

    Science.gov (United States)

    Landscaping practices can positively or negatively affect local environments and human health. The Landscaping Initiative seeks to enhance benefits of landscaping while reducing need for pesticides, fertilizers, etc., by working with partners.

  13. About the RAS Initiative

    Science.gov (United States)

    The RAS Initiative, a "hub and spoke" model, connects researchers to better understand and target the more than 30% of cancers driven by mutations in RAS genes. Includes oversight and contact information.

  14. The Yekaterinburg headache initiative

    DEFF Research Database (Denmark)

    Lebedeva, Elena R; Olesen, Jes; Osipova, Vera V

    2013-01-01

    for a demonstrational interventional project in Russia, undertaken within the Global Campaign against Headache. The initiative proposes three actions: 1) raise awareness of need for improvement; 2) design and implement a three-tier model (from primary care to a single highly specialized centre with academic affiliation......) for efficient and equitable delivery of headache-related health care; 3) develop a range of educational initiatives aimed at primary-care physicians, non-specialist neurologists, pharmacists and the general public to support the second action. RESULTS AND CONCLUSION: We set these proposals in a context...... of a health-care needs assessment, and as a model for all Russia. We present and discuss early progress of the initiative, justify the investment of resources required for implementation and call for the political support that full implementation requires. The more that the Yekaterinburg headache initiative...

  15. The RAS Initiative

    Science.gov (United States)

    NCI established the RAS Initiative to explore innovative approaches for attacking the proteins encoded by mutant forms of RAS genes and to ultimately create effective, new therapies for RAS-related cancers.

  16. Pre-Feasibility Analysis of Pellet Manufacturing on the Former Loring Air Force Base Site. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Hunsberger, R.; Mosey, G.

    2014-04-01

    The U.S. Environmental Protection Agency (EPA) Office of Solid Waste and Emergency Response, in accordance with the RE-Powering America's Lands initiative, engaged the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) to conduct feasibility studies to assess the viability of developing renewable energy generating facilities on contaminated sites. This site, in Limestone, Maine -- formerly the location of the Loring Air Force Base but now owned by the Aroostook Band of Micmac -- was selected for the potential to produce heating pellets from woody feedstock. Biomass was chosen as the renewable energy resource to evaluate based on abundant woody-biomass resources available in the area. NREL also evaluates potential savings from converting existing Micmac property from oil-fired heating to pellet heating.

  17. Piezoelectrically Initiated Pyrotechnic Igniter

    Science.gov (United States)

    Quince, Asia; Dutton, Maureen; Hicks, Robert; Burnham, Karen

    2013-01-01

    This innovation consists of a pyrotechnic initiator and piezoelectric initiation system. The device will be capable of being initiated mechanically; resisting initiation by EMF, RF, and EMI (electromagnetic field, radio frequency, and electromagnetic interference, respectively); and initiating in water environments and space environments. Current devices of this nature are initiated by the mechanical action of a firing pin against a primer. Primers historically are prone to failure. These failures are commonly known as misfires or hang-fires. In many cases, the primer shows the dent where the firing pin struck the primer, but the primer failed to fire. In devices such as "T" handles, which are commonly used to initiate the blowout of canopies, loss of function of the device may result in loss of crew. In devices such as flares or smoke generators, failure can result in failure to spot a downed pilot. The piezoelectrically initiated ignition system consists of a pyrotechnic device that plugs into a mechanical system (activator), which on activation, generates a high-voltage spark. The activator, when released, will strike a stack of electrically linked piezo crystals, generating a high-voltage, low-amperage current that is then conducted to the pyro-initiator. Within the initiator, an electrode releases a spark that passes through a pyrotechnic first-fire mixture, causing it to combust. The combustion of the first-fire initiates a primary pyrotechnic or explosive powder. If used in a "T" handle, the primary would ramp the speed of burn up to the speed of sound, generating a shock wave that would cause a high explosive to go "high order." In a flare or smoke generator, the secondary would produce the heat necessary to ignite the pyrotechnic mixture. The piezo activator subsystem is redundant in that a second stack of crystals would be struck at the same time with the same activation force, doubling the probability of a first strike spark generation. If the first

  18. Supply Chain Initiatives Database

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-11-01

    The Supply Chain Initiatives Database (SCID) presents innovative approaches to engaging industrial suppliers in efforts to save energy, increase productivity and improve environmental performance. This comprehensive and freely-accessible database was developed by the Institute for Industrial Productivity (IIP). IIP acknowledges Ecofys for their valuable contributions. The database contains case studies searchable according to the types of activities buyers are undertaking to motivate suppliers, target sector, organization leading the initiative, and program or partnership linkages.

  19. Energy efficiency initiatives: Indian experience

    Energy Technology Data Exchange (ETDEWEB)

    Dey, Dipankar [ICFAI Business School, Kolkata, (IBS-K) (India)

    2007-07-01

    India, with a population of over 1.10 billion is one of the fastest growing economies of the world. As domestic sources of different conventional commercial energy are drying up, dependence on foreign energy sources is increasing. There exists a huge potential for saving energy in India. After the first 'oil shock' (1973), the government of India realized the need for conservation of energy and a 'Petroleum Conservation Action Group' was formed in 1976. Since then many initiatives aiming at energy conservation and improving energy efficiency, have been undertaken (the establishment of Petroleum Conservation Research Association in 1978; the notification of Eco labelling scheme in 1991; the formation of Bureau of Energy Efficiency in 2002). But no such initiative was successful. In this paper an attempt has been made to analyze the changing importance of energy conservation/efficiency measures which have been initiated in India between 1970 and 2005.The present study tries to analyze the limitations and the reasons of failure of those initiatives. The probable reasons are: fuel pricing mechanism (including subsidies), political factors, corruption and unethical practices, influence of oil and related industry lobbies - both internal and external, the economic situation and the prolonged protection of domestic industries. Further, as India is opening its economy, the study explores the opportunities that the globally competitive market would offer to improve the overall energy efficiency of the economy. The study suggests that the Bureau of Energy Efficiency (BEE) - the newly formed nodal agency for improving energy efficiency of the economy may be made an autonomous institution where intervention from the politicians would be very low. For proper implementation of different initiatives to improve energy efficiency, BEE should involve more the civil societies (NGO) from the inception to the implementation stage of the programs. The paper also

  20. Potential germination and initial growth of Sclerocarya birrea (A ...

    African Journals Online (AJOL)

    SARAH

    2014-04-30

    Apr 30, 2014 ... Methodology: The parameters studied for the germination test were: latency duration, germination capacity .... for family consumption or in the cosmetic industry. (Murray ... the crowns of trees and in the stall of the animals.

  1. Potential sources for initial inoculum and dispersal pattern of ...

    African Journals Online (AJOL)

    With proper scouting on mildew development to determine the timing of first round of fungicide application, it may be possible to reduce the nuinber of applications from the recommended six rounds of sulphur to three or four at sites in these districts. Further studies to determine the impact of off-season immature shoots and ...

  2. An Evaluation of Potential Countermeasures to the Strategic Defense Initiative.

    Science.gov (United States)

    1986-03-01

    of billions of dollars more. Actual costs, of course, cannot be determined until specific systems are selected . Nonetheless, various groups have...problem is to keep the reflective coating covered by a strippable outer wrapper until the booster leaves the lower atmosphere [Ref. 12]. By rotating the

  3. International EUREKA: Initialization Segment

    International Nuclear Information System (INIS)

    1982-02-01

    The Initialization Segment creates the starting description of the uranium market. The starting description includes the international boundaries of trade, the geologic provinces, resources, reserves, production, uranium demand forecasts, and existing market transactions. The Initialization Segment is designed to accept information of various degrees of detail, depending on what is known about each region. It must transform this information into a specific data structure required by the Market Segment of the model, filling in gaps in the information through a predetermined sequence of defaults and built in assumptions. A principal function of the Initialization Segment is to create diagnostic messages indicating any inconsistencies in data and explaining which assumptions were used to organize the data base. This permits the user to manipulate the data base until such time the user is satisfied that all the assumptions used are reasonable and that any inconsistencies are resolved in a satisfactory manner

  4. Initiating events frequency determination

    International Nuclear Information System (INIS)

    Simic, Z.; Mikulicic, V.; Vukovic, I.

    2004-01-01

    The paper describes work performed for the Nuclear Power Station (NPS). Work is related to the periodic initiating events frequency update for the Probabilistic Safety Assessment (PSA). Data for all relevant NPS initiating events (IE) were reviewed. The main focus was on events occurring during most recent operating history (i.e., last four years). The final IE frequencies were estimated by incorporating both NPS experience and nuclear industry experience. Each event was categorized according to NPS individual plant examination (IPE) initiating events grouping approach. For the majority of the IE groups, few, or no events have occurred at the NPS. For those IE groups with few or no NPS events, the final estimate was made by means of a Bayesian update with general nuclear industry values. Exceptions are rare loss-of-coolant-accidents (LOCA) events, where evaluation of engineering aspects is used in order to determine frequency.(author)

  5. RCRA facility stabilization initiative

    International Nuclear Information System (INIS)

    1995-02-01

    The RCRA Facility Stabilization Initiative was developed as a means of implementing the Corrective Action Program's management goals recommended by the RIS for stabilizing actual or imminent releases from solid waste management units that threaten human health and the environment. The overall goal of stabilization is to, as situations warrant, control or abate threats to human health and/or the environment from releases at RCRA facilities, and/or to prevent or minimize the further spread of contamination while long-term remedies are pursued. The Stabilization initiative is a management philosophy and should not be confused with stabilization technologies

  6. University involvement in sustainability initiatives

    DEFF Research Database (Denmark)

    Lehmann, Martin; Christensen, Per; Thrane, Mikkel

    2007-01-01

    With an outset in the case of Aalborg University, the linkages (actual, potential and missing) between academic work in research & education and sustainability initiatives are explored. The focus is both on the university's core activities as a provider of research and education and on the univer......With an outset in the case of Aalborg University, the linkages (actual, potential and missing) between academic work in research & education and sustainability initiatives are explored. The focus is both on the university's core activities as a provider of research and education...... and on the university's activities as an organisation, i.e. its own operation and its accounting for this. Sustainability is defined as a continuous process requiring balance between (the emergence of) problems and our ability and capability to solve them. Some core questions that this paper seeks to answer are: "How...... is Sustainable Development understood at executive level at the university? How (if at all) is sustainable development integrated in the core activities of the university? How is the university attached to ‘real life outside the ivory tower', e.g. through the establishing of Public-Private-Academic Partnerships...

  7. The SEED Initiative

    Science.gov (United States)

    Teich, Carolyn R.

    2011-01-01

    Committed to fulfilling the promise of the green economy, the American Association of Community Colleges (AACC) launched the Sustainability Education and Economic Development (SEED) initiative (www.theseedcenter.org) in October 2010. The project advances sustainability and clean energy workforce development practices at community colleges by…

  8. Major New Initiatives

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Major New Initiatives. Multi-party multi-rate video conferencing OOPS. Live Lecture OOPS. Rural ATM Machine Vortex. Finger print detection HP-IITM. Medical Diagnostic kit NeuroSynaptic. LCD projection system TeNeT. Web Terminal MeTeL Midas. Entertainment ...

  9. Mixed-Initiative Clustering

    Science.gov (United States)

    Huang, Yifen

    2010-01-01

    Mixed-initiative clustering is a task where a user and a machine work collaboratively to analyze a large set of documents. We hypothesize that a user and a machine can both learn better clustering models through enriched communication and interactive learning from each other. The first contribution or this thesis is providing a framework of…

  10. Monolithic exploding foil initiator

    Science.gov (United States)

    Welle, Eric J; Vianco, Paul T; Headley, Paul S; Jarrell, Jason A; Garrity, J. Emmett; Shelton, Keegan P; Marley, Stephen K

    2012-10-23

    A monolithic exploding foil initiator (EFI) or slapper detonator and the method for making the monolithic EFI wherein the exploding bridge and the dielectric from which the flyer will be generated are integrated directly onto the header. In some embodiments, the barrel is directly integrated directly onto the header.

  11. Supersymmetrically transformed periodic potentials

    OpenAIRE

    C, David J. Fernandez

    2003-01-01

    The higher order supersymmetric partners of a stationary periodic potential are studied. The transformation functions associated to the band edges do not change the spectral structure. However, when the transformation is implemented for factorization energies inside of the forbidden bands, the final potential will have again the initial band structure but it can have bound states encrusted into the gaps, giving place to localized periodicity defects.

  12. Next generation initiation techniques

    Science.gov (United States)

    Warner, Tom; Derber, John; Zupanski, Milija; Cohn, Steve; Verlinde, Hans

    1993-01-01

    Four-dimensional data assimilation strategies can generally be classified as either current or next generation, depending upon whether they are used operationally or not. Current-generation data-assimilation techniques are those that are presently used routinely in operational-forecasting or research applications. They can be classified into the following categories: intermittent assimilation, Newtonian relaxation, and physical initialization. It should be noted that these techniques are the subject of continued research, and their improvement will parallel the development of next generation techniques described by the other speakers. Next generation assimilation techniques are those that are under development but are not yet used operationally. Most of these procedures are derived from control theory or variational methods and primarily represent continuous assimilation approaches, in which the data and model dynamics are 'fitted' to each other in an optimal way. Another 'next generation' category is the initialization of convective-scale models. Intermittent assimilation systems use an objective analysis to combine all observations within a time window that is centered on the analysis time. Continuous first-generation assimilation systems are usually based on the Newtonian-relaxation or 'nudging' techniques. Physical initialization procedures generally involve the use of standard or nonstandard data to force some physical process in the model during an assimilation period. Under the topic of next-generation assimilation techniques, variational approaches are currently being actively developed. Variational approaches seek to minimize a cost or penalty function which measures a model's fit to observations, background fields and other imposed constraints. Alternatively, the Kalman filter technique, which is also under investigation as a data assimilation procedure for numerical weather prediction, can yield acceptable initial conditions for mesoscale models. The

  13. Naval Station Newport Wind Resource Assessment. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites, and The Naval Facilities Engineering Service Center

    Energy Technology Data Exchange (ETDEWEB)

    Robichaud, R.; Fields, J.; Roberts, J. O.

    2012-02-01

    The U.S. Environmental Protection Agency (EPA) launched the RE-Powering America's Land initiative to encourage development of renewable energy (RE) on potentially contaminated land and mine sites. EPA is collaborating with the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL) to evaluate RE options at Naval Station (NAVSTA) Newport in Newport, Rhode Island where multiple contaminated areas pose a threat to human health and the environment. Designated a superfund site on the National Priorities List in 1989, the base is committed to working toward reducing the its dependency on fossil fuels, decreasing its carbon footprint, and implementing RE projects where feasible. The Naval Facilities Engineering Service Center (NFESC) partnered with NREL in February 2009 to investigate the potential for wind energy generation at a number of Naval and Marine bases on the East Coast. NAVSTA Newport was one of several bases chosen for a detailed, site-specific wind resource investigation. NAVSTA Newport, in conjunction with NREL and NFESC, has been actively engaged in assessing the wind resource through several ongoing efforts. This report focuses on the wind resource assessment, the estimated energy production of wind turbines, and a survey of potential wind turbine options based upon the site-specific wind resource.

  14. Funding Initiatives | Women in Science | Initiatives | Indian Academy ...

    Indian Academy of Sciences (India)

    Home; Initiatives; Women in Science; Funding Initiatives ... The Fellowship Scheme for Women Scientists for societal programmes is initiative of the ... at a young age of 52, after a valiant battle with cancer, today on 29th March 2016 in Delhi.

  15. Sustaining Participatory Design Initiatives

    DEFF Research Database (Denmark)

    Iversen, Ole Sejer; Dindler, Christian

    2014-01-01

    While many participatory design (PD) projects succeed in establishing new organisational initiatives or creating technology that is attuned to the people affected, the issue of how such results are sustained after the project ends remains an important challenge. We explore the challenge...... these various forms of sustainability may be pursued in PD practice and how they can become a resource in reflecting on PD activities. Finally, we discuss implications for PD practice, suggesting that a nuanced conception of sustainability and how it may relate to PD practice are useful resources for designers...... of sustaining PD initiatives beyond the individual project and discuss implications for PD practice. First, based on current PD literature, we distinguish between four ideal typical forms of sustainability: maintaining, scaling, replicating and evolving. Second, we demonstrate from a case study how...

  16. Initial management of breastfeeding.

    Science.gov (United States)

    Sinusas, K; Gagliardi, A

    2001-09-15

    Breast milk is widely accepted as the ideal source of nutrition for infants. In order to ensure success in breastfeeding, it is important that it be initiated as early as possible during the neonatal period. This is facilitated by skin-to-skin contact between the mother and infant immediately following birth. When possible, the infant should be allowed to root and latch on spontaneously within the first hour of life. Many common nursery routines such as weighing the infant, administration of vitamin K and application of ocular antibiotics can be safely delayed until after the initial breastfeeding. Postpartum care practices that improve breastfeeding rates include rooming-in, anticipatory guidance about breastfeeding problems and the avoidance of formula supplementation and pacifiers.

  17. Self-initiated expatriates

    DEFF Research Database (Denmark)

    Selmer, Jan; Lauring, Jakob

    2014-01-01

    Purpose – As it has been suggested that adult third-culture kids may be more culturally adaptable than others, they have been labelled “the ideal” expatriates. In this article, we explore the adjustment of self-initiated expatriate academics in Hong Kong, comparing adult third-culture kids...... with adult mono-culture kids. Design/methodology/approach – We use survey results from 267 self-initiated expatriate academics in Hong Kong. Findings – Exploratory results show that adult third-culture kids had a higher extent of general adjustment. No significant results were found in relation...... to interaction adjustment and job adjustment. We also found that recent expatriate experiences generally had a positive association with the adjustment of adult mono-culture kids, but this association only existed in terms of general adjustment for adult third-culture kids. Originality/value – Once corroborated...

  18. INITIAL TRAINING OF RESEARCHERS

    Directory of Open Access Journals (Sweden)

    Karina Alejandra Cruz-Pallares

    2015-07-01

    Full Text Available The document presents results of a research that used as strategy a complementary training project with thirty-three students of a Bachelors Degree in Primary School 1997(DPS,1997 of an Education Faculty for the initial training of investigators, applied by four teachers members of the academic research group in Mexico; that develops through process of action research methodology. Highlighted in results is the strengthening of the competition of reading, understanding and writing scientific texts, which is analogous to the first feature of the graduate profile called intellectual skills. Among the conclusions it is emphasized that the initial training of teachers in a task that is quite interesting, challenging and complex, as is the educational complex phenomenon.

  19. Financial planning for major initiatives: a framework for success.

    Science.gov (United States)

    Harris, John M

    2007-11-01

    A solid framework for assessing a major strategic initiative consists of four broad steps: Initial considerations, including level of analysis required and resources that will be brought to bear. Preliminary financial estimates for board approval to further assess the initiative. Assessment of potential partners' interest in the project. Feasibility analysis for board green light.

  20. The hydrogen mine introduction initiative

    Energy Technology Data Exchange (ETDEWEB)

    Betournay, M.C.; Howell, B. [Natural Resources Canada, Ottawa, ON (Canada). CANMET Mining and Mineral Sciences Laboratories

    2009-07-01

    In an effort to address air quality concerns in underground mines, the mining industry is considering the use fuel cells instead of diesel to power mine production vehicles. The immediate issues and opportunities associated with fuel cells use include a reduction in harmful greenhouse gas emissions; reduction in ventilation operating costs; reduction in energy consumption; improved health benefits; automation; and high productivity. The objective of the hydrogen mine introduction initiative (HMII) is to develop and test the range of fundamental and needed operational technology, specifications and best practices for underground hydrogen power applications. Although proof of concept studies have shown high potential for fuel cell use, safety considerations must be addressed, including hydrogen behaviour in confined conditions. This presentation highlighted the issues to meet operational requirements, notably hydrogen production; delivery and storage; mine regulations; and hydrogen behaviour underground. tabs., figs.

  1. DIPS space exploration initiative safety

    International Nuclear Information System (INIS)

    Dix, T.E.

    1991-01-01

    The Dynamic Isotope Power Subsystem has been identified for potential applications for the Space Exploration Initiative. A qualitative safety assessment has been performed to demonstrate the overall safety adequacy of the Dynamic Isotope Power Subsystem for these applications. Mission profiles were defined for reference lunar and martian flights. Accident scenarios were qualitatively defined for all mission phases. Safety issues were then identified. The safety issues included radiation exposure, fuel containment, criticality, diversion, toxic materials, heat flux to the extravehicular mobility unit, and disposal. The design was reviewed for areas where safety might be further improved. Safety would be improved by launching the fuel separate from the rest of the subsystem on expendable launch vehicles, using a fuel handling tool during unloading of the hot fuel canister, and constructing a cage-like structure around the reversible heat removal system lithium heat pipes. The results of the safety assessment indicate that the DIPS design with minor modifications will produce a low risk concept

  2. Hawaii Energy and Environmental Technologies (HEET) Initiative

    Science.gov (United States)

    2011-12-01

    polymer electrolyte fuel cells ( PEMFCs ) performance. This work was performed to support the DOE manufacturing initiative for PEMFC production. The work...performed by exposing the MEA cathode to 10 ppm SO2 in N2 at certain potential and typical operating conditions of a PEMFC for certain time, then...adsorbate by analyzing the electrochemical reduction and oxidation potential and charge. As for the in-situ SO2 adsorption experiments, a PEMFC under

  3. Hanford tanks initiative plan

    International Nuclear Information System (INIS)

    McKinney, K.E.

    1997-01-01

    Abstract: The Hanford Tanks Initiative (HTI) is a five-year project resulting from the technical and financial partnership of the U.S. Department of Energy's Office of Waste Management (EM-30) and Office of Science and Technology Development (EM-50). The HTI project accelerates activities to gain key technical, cost performance, and regulatory information on two high-level waste tanks. The HTI will provide a basis for design and regulatory decisions affecting the remainder of the Tank Waste Remediation System's tank waste retrieval Program

  4. UNLV Nuclear Hydrogen Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Hechanova, Anthony E.; Johnson, Allen; O' Toole, Brendan; Trabia, Mohamed; Peterson, Per

    2012-10-25

    Evaluation of the Crack growth rate (CGR) of Alloy 617 and Alloy 276 under constant K at ambient temperature has been completed. Creep deformation of Alloy 230 at different temperature range and load level has been completed and heat to heat variation has been noticed. Creep deformation study of Alloy 276 has been completed under an applied initial stress level of 10% of yield stress at 950ºC. The grain size evaluation of the tested creep specimens of Alloy 276 has been completed.

  5. Feedback stabilization initiative

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    Much progress has been made in attaining high confinement regimes in magnetic confinement devices. These operating modes tend to be transient, however, due to the onset of MHD instabilities, and their stabilization is critical for improved performance at steady state. This report describes the Feedback Stabilization Initiative (FSI), a broad-based, multi-institutional effort to develop and implement methods for raising the achievable plasma betas through active MHD feedback stabilization. A key element in this proposed effort is the Feedback Stabilization Experiment (FSX), a medium-sized, national facility that would be specifically dedicated to demonstrating beta improvement in reactor relevant plasmas by using a variety of MHD feedback stabilization schemes.

  6. Feedback stabilization initiative

    International Nuclear Information System (INIS)

    1997-06-01

    Much progress has been made in attaining high confinement regimes in magnetic confinement devices. These operating modes tend to be transient, however, due to the onset of MHD instabilities, and their stabilization is critical for improved performance at steady state. This report describes the Feedback Stabilization Initiative (FSI), a broad-based, multi-institutional effort to develop and implement methods for raising the achievable plasma betas through active MHD feedback stabilization. A key element in this proposed effort is the Feedback Stabilization Experiment (FSX), a medium-sized, national facility that would be specifically dedicated to demonstrating beta improvement in reactor relevant plasmas by using a variety of MHD feedback stabilization schemes

  7. Initiation of slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Hanratty, T.J.; Woods, B.D. [Univ. of Illinois, Urbana, IL (United States)

    1995-12-31

    The initiation of slug flow in a horizontal pipe can be predicted either by considering the stability of a slug or by considering the stability of a stratified flow. Measurements of the shedding rate of slugs are used to define necessary conditions for the existence of a slug. Recent results show that slugs develop from an unstable stratified flow through the evolution of small wavelength waves into large wavelength waves that have the possibility of growing to form a slug. The mechanism appears to be quite different for fluids with viscosities close to water than for fluids with large viscosities (20 centipoise).

  8. Initiating statistical maintenance optimization

    International Nuclear Information System (INIS)

    Doyle, E. Kevin; Tuomi, Vesa; Rowley, Ian

    2007-01-01

    Since the 1980 s maintenance optimization has been centered around various formulations of Reliability Centered Maintenance (RCM). Several such optimization techniques have been implemented at the Bruce Nuclear Station. Further cost refinement of the Station preventive maintenance strategy includes evaluation of statistical optimization techniques. A review of successful pilot efforts in this direction is provided as well as initial work with graphical analysis. The present situation reguarding data sourcing, the principle impediment to use of stochastic methods in previous years, is discussed. The use of Crowe/AMSAA (Army Materials Systems Analysis Activity) plots is demonstrated from the point of view of justifying expenditures in optimization efforts. (author)

  9. Wavepacket scattering in potential theory

    International Nuclear Information System (INIS)

    Weber, T.A.; Hammer, C.L.

    1977-01-01

    A contour integration technique is developed which enforces the initial conditions for wavepacket-potential scattering. The expansion coefficients for the exact energy eigenstate expansion are automatically expressed in terms of the plane wave expansion coefficients of the initial wavepacket, thereby simplifying what is usually a tedious, mathematical process. The method is applicable regardless of the initial spatial separation of the wavepacket from the scattering center

  10. The LHCb Starterkit initiative

    CERN Document Server

    Puig Navarro, Albert

    2017-01-01

    The vast majority of high-energy physicists use and produce software every day. Software skills are usually acquired on the go and dedicated training courses are rare. The LHCb Starterkit is a new training format for getting LHCb collaborators started in effectively using software to perform their research. The initiative, combining courses and online tutorials, focuses on teaching basic skills for research computing, as well as LHCb software specifics. Unlike traditional tutorials we focus on starting with basics, performing all the material live, with a high degree of interactivity, giving priority to understanding the tools as opposed to handing out recipes that work “as if by magic”. The LHCb Starterkit was started by young members of the collaboration inspired by the principles of Software Carpentry, and the material is created in a collaborative fashion using the tools we teach. Three successful entry-level workshops, as well as two advanced ones, have taken place since the start of the initiative i...

  11. Initiatives for proliferation prevention

    International Nuclear Information System (INIS)

    1997-04-01

    Preventing the proliferation of weapons of mass destruction is a central part of US national security policy. A principal instrument of the Department of Energy's (DOE's) program for securing weapons of mass destruction technology and expertise and removing incentives for scientists, engineers and technicians in the newly independent states (NIS) of the former Soviet Union to go to rogue countries or assist terrorist groups is the Initiatives for Proliferation Prevention (IPP). IPP was initiated pursuant to the 1994 Foreign Operations Appropriations Act. IPP is a nonproliferation program with a commercialization strategy. IPP seeks to enhance US national security and to achieve nonproliferation objectives by engaging scientists, engineers and technicians from former NIS weapons institutes; redirecting their activities in cooperatively-developed, commercially viable non-weapons related projects. These projects lead to commercial and economic benefits for both the NIS and the US IPP projects are funded in Russian, Ukraine, Kazakhstan and Belarus. This booklet offers an overview of the IPP program as well as a sampling of some of the projects which are currently underway

  12. View all initiatives | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Initiative. The Cultivate Africa's Future research partnership is designed to support applied research to combat hunger in sub-Saharan Africa by harnessing the potential for innovation among the region's smallholder farmers, the majority of whom are women. We fund researchers driving global change. Careers · Contact Us ...

  13. Small Spacecraft Technology Initiative Education Program

    Science.gov (United States)

    1995-01-01

    A NASA engineer with the Commercial Remote Sensing Program (CRSP) at Stennis Space Center works with students from W.P. Daniels High School in New Albany, Miss., through NASA's Small Spacecraft Technology Initiative Program. CRSP is teaching students to use remote sensing to locate a potential site for a water reservoir to offset a predicted water shortage in the community's future.

  14. Understanding the Sustainability of Private Development Initiatives

    NARCIS (Netherlands)

    Kinsbergen, Sara; Schulpen, Lau; Ruben, Ruerd

    2017-01-01

    In the Netherlands, there is a large group of small-scale, voluntary development organisations, referred to as Private Development Initiatives (PDIs). By classifying PDI interventions based on their potential sustainability, we aim to enhance our understanding of PDIs as alternative development

  15. Innovation Initiatives in Large Software Companies

    DEFF Research Database (Denmark)

    Edison, Henry; Wang, Xiaofeng; Jabangwe, Ronald

    2018-01-01

    empirical studies on innovation initiative in the context of large software companies. A total of 7 studies are conducted in the context of large software companies, which reported 5 types of initiatives: intrapreneurship, bootlegging, internal venture, spin-off and crowdsourcing. Our study offers three......Context: To keep the competitive advantage and adapt to changes in the market and technology, companies need to innovate in an organised, purposeful and systematic manner. However, due to their size and complexity, large companies tend to focus on the structure in maintaining their business, which...... can potentially lower their agility to innovate. Objective:The aims of this study are to provide an overview of the current research on innovation initiatives and to identify the challenges of implementing those initiatives in the context of large software companies. Method: The investigation...

  16. Evaluation Program initiative

    International Nuclear Information System (INIS)

    Rich, B.L.

    1987-01-01

    The purpose of this paper is to provide the Department of Energy's (DOE) safeguards and security community with some insights on an important management initiative by the Office of Security Evaluations (OSE). The paper will present the ''what, where, who, when, and why'' of a new Evaluation Program. The Evaluation Program will be comprised of a continuing series of regular and special evaluations of DOE safeguards and security programs and policies. The evaluations will be integrative and ''crosscutting,'' i.e. will extend across DOE organizational lines. Evaluations will be offered as positive advisories to DOE managers with safeguards and security responsibilities and will not be rated. They will complement the ongoing OSE Inspection Program of inspections conducted by OSE's Inspection Division. The purpose for the evaluations is to establish an accurate and current assessment of the effectiveness and status of safeguards and security programs and policies and to provide DOE managers with required information on program and policy effectiveness

  17. Breckinridge Project, initial effort

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1982-09-01

    Report III, Volume 1 contains those specifications numbered A through J, as follows: General Specifications (A); Specifications for Pressure Vessels (C); Specifications for Tanks (D); Specifications for Exchangers (E); Specifications for Fired Heaters (F); Specifications for Pumps and Drivers (G); and Specifications for Instrumentation (J). The standard specifications of Bechtel Petroleum Incorporated have been amended as necessary to reflect the specific requirements of the Breckinridge Project, and the more stringent specifications of Ashland Synthetic Fuels, Inc. These standard specifications are available to the Initial Effort (Phase Zero) work performed by all contractors and subcontractors. Report III, Volume 1 also contains the unique specifications prepared for Plants 8, 15, and 27. These specifications will be substantially reviewed during Phase I of the project, and modified as necessary for use during the engineering, procurement, and construction of this project.

  18. The climate technology initiative

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Adam [International Energy Agency, Climate Technology Initiative, Paris (France)

    2000-12-01

    The CTI (Climate Technology Initiative) aims to promote those technologies which cause the minimum of harm to the environment: reducing emissions of greenhouse gases and supporting those countries most vulnerable to climate change are priorities. A strong case for cogeneration is made and it is pointed out that both the European Union and the USA aim to double their cogeneration capacity by 2010. The CTI holds training courses and seminars all over the world where the barriers to the expansion of climate-friendly technology are discussed. The article also mentions the CTI Co-operation Technology Implementation Plan, research and development, its website and search engine, its presence at all UNFCCC events and its awards programme.

  19. The climate technology initiative

    International Nuclear Information System (INIS)

    Smith, Adam

    2000-01-01

    The CTI (Climate Technology Initiative) aims to promote those technologies which cause the minimum of harm to the environment: reducing emissions of greenhouse gases and supporting those countries most vulnerable to climate change are priorities. A strong case for cogeneration is made and it is pointed out that both the European Union and the USA aim to double their cogeneration capacity by 2010. The CTI holds training courses and seminars all over the world where the barriers to the expansion of climate-friendly technology are discussed. The article also mentions the CTI Co-operation Technology Implementation Plan, research and development, its website and search engine, its presence at all UNFCCC events and its awards programme

  20. Initial brain aging

    DEFF Research Database (Denmark)

    Thomsen, Kirsten; Yokota, Takashi; Hasan-Olive, Md Mahdi

    2018-01-01

    Brain aging is accompanied by declining mitochondrial respiration. We hypothesized that mitochondrial morphology and dynamics would reflect this decline. Using hippocampus and frontal cortex of a segmental progeroid mouse model lacking Cockayne syndrome protein B (CSB(m/m)) and C57Bl/6 (WT......) controls and comparing young (2-5 months) to middle-aged mice (13-14 months), we found that complex I-linked state 3 respiration (CI) was reduced at middle age in CSB(m/m) hippocampus, but not in CSB(m/m) cortex or WT brain. In hippocampus of both genotypes, mitochondrial size heterogeneity increased....... Mitochondrial DNA content was lower, and hypoxia-induced factor 1α mRNA was greater at both ages in CSB(m/m) compared to WT brain. Our findings show that decreased CI and increased mitochondrial size heterogeneity are highly associated and point to declining mitochondrial quality control as an initial event...

  1. Materials Genome Initiative

    Science.gov (United States)

    Vickers, John

    2015-01-01

    The Materials Genome Initiative (MGI) project element is a cross-Center effort that is focused on the integration of computational tools to simulate manufacturing processes and materials behavior. These computational simulations will be utilized to gain understanding of processes and materials behavior to accelerate process development and certification to more efficiently integrate new materials in existing NASA projects and to lead to the design of new materials for improved performance. This NASA effort looks to collaborate with efforts at other government agencies and universities working under the national MGI. MGI plans to develop integrated computational/experimental/ processing methodologies for accelerating discovery and insertion of materials to satisfy NASA's unique mission demands. The challenges include validated design tools that incorporate materials properties, processes, and design requirements; and materials process control to rapidly mature emerging manufacturing methods and develop certified manufacturing processes

  2. The Ombudperson Initiative Group

    CERN Multimedia

    Laura Stewart

    Following many discussions that took place at some of the ATLAS Women's Network lunch gatherings, a few ATLAS women joined forces with similarly concerned CERN staff women to form a small group last Fall to discuss the need for a CERN-wide Ombudsperson. This has since evolved into the Ombudsperson Initiative Group (OIG) currently composed of the following members: Barbro Asman, Stockholm University; Pierre Charrue, CERN AB; Anna Cook, CERN IT; Catherine Delamare, CERN and IT Ombudsperson; Paula Eerola, Lund University; Pauline Gagnon, Indiana University; Eugenia Hatziangeli, CERN AB; Doreen Klem, CERN IT; Bertrand Nicquevert, CERN TS and Laura Stewart, CERN AT. On June 12, members of the OIG met with representatives of Human Resources (HR) and the Equal Opportunity Advisory Panel (EOAP) to discuss the proposal drafted by the OIG. The meeting was very positive. Everybody agreed that the current procedures at CERN applicable in the event of conflict required a thorough review, and that a professionnally trai...

  3. Instrumented Pipeline Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Piro; Michael Ream

    2010-07-31

    This report summarizes technical progress achieved during the cooperative agreement between Concurrent Technologies Corporation (CTC) and U.S. Department of Energy to address the need for a for low-cost monitoring and inspection sensor system as identified in the Department of Energy (DOE) National Gas Infrastructure Research & Development (R&D) Delivery Reliability Program Roadmap.. The Instrumented Pipeline Initiative (IPI) achieved the objective by researching technologies for the monitoring of pipeline delivery integrity, through a ubiquitous network of sensors and controllers to detect and diagnose incipient defects, leaks, and failures. This report is organized by tasks as detailed in the Statement of Project Objectives (SOPO). The sections all state the objective and approach before detailing results of work.

  4. The Enzyme Function Initiative.

    Science.gov (United States)

    Gerlt, John A; Allen, Karen N; Almo, Steven C; Armstrong, Richard N; Babbitt, Patricia C; Cronan, John E; Dunaway-Mariano, Debra; Imker, Heidi J; Jacobson, Matthew P; Minor, Wladek; Poulter, C Dale; Raushel, Frank M; Sali, Andrej; Shoichet, Brian K; Sweedler, Jonathan V

    2011-11-22

    The Enzyme Function Initiative (EFI) was recently established to address the challenge of assigning reliable functions to enzymes discovered in bacterial genome projects; in this Current Topic, we review the structure and operations of the EFI. The EFI includes the Superfamily/Genome, Protein, Structure, Computation, and Data/Dissemination Cores that provide the infrastructure for reliably predicting the in vitro functions of unknown enzymes. The initial targets for functional assignment are selected from five functionally diverse superfamilies (amidohydrolase, enolase, glutathione transferase, haloalkanoic acid dehalogenase, and isoprenoid synthase), with five superfamily specific Bridging Projects experimentally testing the predicted in vitro enzymatic activities. The EFI also includes the Microbiology Core that evaluates the in vivo context of in vitro enzymatic functions and confirms the functional predictions of the EFI. The deliverables of the EFI to the scientific community include (1) development of a large-scale, multidisciplinary sequence/structure-based strategy for functional assignment of unknown enzymes discovered in genome projects (target selection, protein production, structure determination, computation, experimental enzymology, microbiology, and structure-based annotation), (2) dissemination of the strategy to the community via publications, collaborations, workshops, and symposia, (3) computational and bioinformatic tools for using the strategy, (4) provision of experimental protocols and/or reagents for enzyme production and characterization, and (5) dissemination of data via the EFI's Website, http://enzymefunction.org. The realization of multidisciplinary strategies for functional assignment will begin to define the full metabolic diversity that exists in nature and will impact basic biochemical and evolutionary understanding, as well as a wide range of applications of central importance to industrial, medicinal, and pharmaceutical efforts.

  5. Green Power Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Butler, Patrick Barry [Univ. of Iowa, Iowa City, IA (United States)

    2013-01-28

    National energy policy supports the gathering of more detailed and authoritative data on the introduction of renewable bio-based fuels into new and existing district energy systems via the application of biomass gasification. The University of Iowa developed a biomass-fueled, university-scale steam generation system based on biomass gasification technologies. The system serves as a state-of-the-art research and educational facility in the emerging application of gasification in steam generation. The facility, which includes a smaller down-draft gasifier and a larger multi-stage biomass boiler, was designed to operate primarily on wood-based fuels, but has provisions for testing other biomass fuel sources produced within a 100-mile radius, providing enough flexibility to meet the fluctuating local supply of biomass from industry and Midwest agriculture. The equipment was installed in an existing, staffed facility. The down-draft gasifier unit is operated by College of Engineering staff and students, under the direct technical supervision of qualified Utilities plant staff. The Green Power Initiative also includes a substantial, innovative educational component. In addition to an onsite, graduate-level research program in biomass fuels, the investigators have integrated undergraduate and graduate level teaching – through classroom studies and experiential learning – and applied research into a biomass-based, university-scale, functioning power plant. University of Iowa is unique in that it currently has multiple renewable energy technologies deployed, including significant biomass combustion (oat hulls) at its Main Power Plant and a new reciprocating engine based renewable district energy system. This project complements and supports the national energy policy and State of Iowa initiatives in ethanol and biodiesel. Byproducts of ethanol and biodiesel processes (distiller grains) as well as industry residues (oat hulls, wood chips, construction and demolition

  6. A mechanical energy analysis of gait initiation

    Science.gov (United States)

    Miller, C. A.; Verstraete, M. C.

    1999-01-01

    The analysis of gait initiation (the transient state between standing and walking) is an important diagnostic tool to study pathologic gait and to evaluate prosthetic devices. While past studies have quantified mechanical energy of the body during steady-state gait, to date no one has computed the mechanical energy of the body during gait initiation. In this study, gait initiation in seven normal male subjects was studied using a mechanical energy analysis to compute total body energy. The data showed three separate states: quiet standing, gait initiation, and steady-state gait. During gait initiation, the trends in the energy data for the individual segments were similar to those seen during steady-state gait (and in Winter DA, Quanbury AO, Reimer GD. Analysis of instantaneous energy of normal gait. J Biochem 1976;9:253-257), but diminished in amplitude. However, these amplitudes increased to those seen in steady-state during the gait initiation event (GIE), with the greatest increase occurring in the second step due to the push-off of the foundation leg. The baseline level of mechanical energy was due to the potential energy of the individual segments, while the cyclic nature of the data was indicative of the kinetic energy of the particular leg in swing phase during that step. The data presented showed differences in energy trends during gait initiation from those of steady state, thereby demonstrating the importance of this event in the study of locomotion.

  7. Potential Theory

    CERN Document Server

    Lukeš, Jaroslav; Netuka, Ivan; Veselý, Jiří

    1988-01-01

    Within the tradition of meetings devoted to potential theory, a conference on potential theory took place in Prague on 19-24, July 1987. The Conference was organized by the Faculty of Mathematics and Physics, Charles University, with the collaboration of the Institute of Mathematics, Czechoslovak Academy of Sciences, the Department of Mathematics, Czech University of Technology, the Union of Czechoslovak Mathematicians and Physicists, the Czechoslovak Scientific and Technical Society, and supported by IMU. During the Conference, 69 scientific communications from different branches of potential theory were presented; the majority of them are in­ cluded in the present volume. (Papers based on survey lectures delivered at the Conference, its program as well as a collection of problems from potential theory will appear in a special volume of the Lecture Notes Series published by Springer-Verlag). Topics of these communications truly reflect the vast scope of contemporary potential theory. Some contributions deal...

  8. Potential bags

    International Nuclear Information System (INIS)

    Ferreira, P.L.; Tomio, L.

    1992-01-01

    In this paper, relativistic confining potential models, endowed with bag constants associated to volume energy terms, are investigated. In contrast to the usual bag model, these potential bags are distinguished by having smeared bag surfaces. Based on the dynamical assumptions underlying the fuzzy bag model, these bag constants are derived from the corresponding energy-momentum tensor. Explicit expressions for the single-quark energies and for the nucleon bag constant are obtained by means of an improved analytical version of the saddle-point variational method for the Dirac equation with confining power-law potentials of the scalar plus vector (S + V) or pure scalar (S) type

  9. Initial Egyptian ECMO experience

    Directory of Open Access Journals (Sweden)

    Akram Abdelbary

    2016-04-01

    Results: A total of twelve patients received ECMO between January 2014 and June 2015. The mean age was 35.9 years. (range 13–65 years, 8 males, with VV ECMO in 10 patients, and VA ECMO in 2 patients. Out of ten patients of VV ECMO, one had H1N1 pneumonia, one had advanced vasculitic lung, four had bacterial pneumonia, two traumatic lung contusions and one with organophosphorus poisoning, and one undiagnosed etiology leading to severe ARDS. Lung injury score range was 3–3.8, PaO2/FiO2 (20–76 mechanical ventilation duration before ECMO 1–14 days, Femoro-jugular cannulation in 7 patients and femoro-femoral in 2 patients and femoro-subclavian in 1 patient; all patients were initially sedated and paralyzed for (2–4 days and ventilated on pressure controlled ventilation with Pmax of 25 cm H2O and PEEP of 10 cm H2O. In VA ECMO patients were cannulated percutaneously using femoro-femoral approach. One patient showed no neurologic recovery and died after 24 h, the other had CABG on ECMO however the heart didn’t recover and died after 9 days. Heparin intravenous infusion was used initially in all patients and changed to Bivalirudin in 2 patients due to possible HIT. Pump flow ranged from 2.6 to 6.5 L/min. Average support time was 12 days (range 2–24 days. Seven patients (63.3% were successfully separated from ECMO and survived to hospital discharge. Hospital length of stay ranged from 3 to 42 days, tracheostomy was done percutaneously in 5 patients and surgically in 3. Gastrointestinal bleeding occurred in 6 patients, VAP in 7 patients, neurologic complications in 1 patient with complete recovery, cardiac arrhythmias in 3 patients, pneumothorax in 9 patients, and deep venous thrombosis in 2 patients.

  10. TFTR initial operations

    International Nuclear Information System (INIS)

    Young, K.M.; Bell, M.; Blanchard, W.R.

    1984-01-01

    TFTR (Tokamak Fusion Test Reactor) has operated since December 1982 with ohmically heated plasmas. Routine operation with feedback control of plasma current, position and density has been obtained for plasmas with Isub(p) approx.= 800 kA, a = 68 cm, R = 250 cm, and Bsub(t) = 27 kG. A maximum plasma current of 1 MA was achieved with q approx.= 2.5. Energy confinement times of approx. 150 msec were measured for hydrogen and deuterium plasmas with n-barsub(e) approx.= 2 x 10 13 cm -3 , Tsub(e)(O) approx.= 1.5 keV, Tsub(i)(O) approx.= 1.5 keV and Zsub(eff) approx.= 3. The preliminary results suggest a size-cubed scaling from PLT, and are consistent with Alcator C scaling where tau approx. nR 2 a. Initial measurements of plasma disruption characteristics indicate current decay rates of approx. 800 kA in 8 ms which is within the TFTR design requirement of 3 MA in 3 ms. (author)

  11. The new childcare initiative

    CERN Multimedia

    Cigdem Issever

    The ATLAS Women's Network recently sent out a general mailing to all ATLAS and CMS members to announce a new initiative aimed at improving childcare facilities for Users coming to CERN. Several people have expressed the need that CERN should provide or facilitate affordable day care for children of temporary visitors at CERN. The ATLAS Women's Network is now forming a child care task force from concerned people and invites all those interested to join this effort. You can do so by either adding your name to the mailing list cern-users-childcare@cern.ch in Simba or by contacting Cigdem.Issever@cern.NOSPAM.ch and Pauline.Gagnon@cern.NOSPAM.ch. More than 50 people have already joined this effort. Those who have joined the mailing list will soon receive all the details about the next conference call meeting which has been scheduled for Thursday October 25th from 16:30 to 18:00 CERN time. The preliminary agenda is the following: Summary of our first contact of ATLAS and CMS (5 min) Discussion about the co-conv...

  12. AECL's new environmental initiatives

    International Nuclear Information System (INIS)

    McDonnell, F.N.

    1993-01-01

    AECL's research and development expenditures in environmental sciences and waste management technology are about $50 M per year. The main focus of these programs is the Nuclear Fuel Waste Management Program. This research is supplemented by activities in support of laboratory, Environmental Authority and internal waste management requirements, as well as provision of non-nuclear services. AECL intends to become more involved in performing environmental research and development with broader application. The goal is to achieve a relationship with Canadian industry that would involve a substantial portion of AECL's environmental research capabilities. The research directions and priorities of the resulting partnership would be set by the private sector in accordance with their needs and requirements. It is expected that the activities associated with this new environmental initiative will start small and grow in response to perceived needs. AECL is now increasing its non-nuclear research efforts by targeting those markets that appear most attractive. The thrust can be divided into three broad categories: environmental research, environmental services, and environmental products. (Author)

  13. TFTR initial operations

    International Nuclear Information System (INIS)

    Young, K.M.; Bell, M.; Blanchard, W.R.

    1983-11-01

    The Tokamak Fusion Test Reactor (TFTR) has operated since December 1982 with ohmically heated plasmas. Routine operation with feedback control of plasma current, position, and density has been obtained for plasmas with I/sub p/ approx. = 800 kA, a = 68 cm, R = 250 cm, and B/sub t/ = 27 kG. A maximum plasma current of 1 MA was achieved with q approx. = 2.5. Energy confinement times of approx. 150 msec were measured for hydrogen and deuterium plasmas with anti n/sub e/ approx. = 2 x 10 13 cm -3 , T/sub e/ (0) approx. = 1.5 keV, T/sub i/ (0) approx. = 1.5 keV, and Z/sub eff/ approx. = 3. The preliminary results suggest a size-cubed scaling from PLT and are consistent with Alcator C scaling where tau approx. nR 2 a. Initial measurements of plasma disruption characteristics indicate current decay rates of approx. 800 kA in 8 ms which is within the TFTR design requirement of 3 MA in 3 ms

  14. Groundwater Potential

    African Journals Online (AJOL)

    big timmy

    4Department of Geology, Ekiti State University, Ado-Ekiti, Nigeria. Corresponding ... integrated for the classification of the study area into different groundwater potential zones. .... table is mainly controlled by subsurface movement of water into ...

  15. Initial conditions for critical Higgs inflation

    Science.gov (United States)

    Salvio, Alberto

    2018-05-01

    It has been pointed out that a large non-minimal coupling ξ between the Higgs and the Ricci scalar can source higher derivative operators, which may change the predictions of Higgs inflation. A variant, called critical Higgs inflation, employs the near-criticality of the top mass to introduce an inflection point in the potential and lower drastically the value of ξ. We here study whether critical Higgs inflation can occur even if the pre-inflationary initial conditions do not satisfy the slow-roll behavior (retaining translation and rotation symmetries). A positive answer is found: inflation turns out to be an attractor and therefore no fine-tuning of the initial conditions is necessary. A very large initial Higgs time-derivative (as compared to the potential energy density) is compensated by a moderate increase in the initial field value. These conclusions are reached by solving the exact Higgs equation without using the slow-roll approximation. This also allows us to consistently treat the inflection point, where the standard slow-roll approximation breaks down. Here we make use of an approach that is independent of the UV completion of gravity, by taking initial conditions that always involve sub-planckian energies.

  16. A methodology for analyzing precursors to earthquake-initiated and fire-initiated accident sequences

    International Nuclear Information System (INIS)

    Budnitz, R.J.; Lambert, H.E.; Apostolakis, G.

    1998-04-01

    This report covers work to develop a methodology for analyzing precursors to both earthquake-initiated and fire-initiated accidents at commercial nuclear power plants. Currently, the U.S. Nuclear Regulatory Commission sponsors a large ongoing project, the Accident Sequence Precursor project, to analyze the safety significance of other types of accident precursors, such as those arising from internally-initiated transients and pipe breaks, but earthquakes and fires are not within the current scope. The results of this project are that: (1) an overall step-by-step methodology has been developed for precursors to both fire-initiated and seismic-initiated potential accidents; (2) some stylized case-study examples are provided to demonstrate how the fully-developed methodology works in practice, and (3) a generic seismic-fragility date base for equipment is provided for use in seismic-precursors analyses. 44 refs., 23 figs., 16 tabs

  17. European nuclear education initiatives

    International Nuclear Information System (INIS)

    Glatz, Jean-Paul

    2011-01-01

    Whatever option regarding their future nuclear energy development is chosen by European Union Member States, the availability of a sufficient number of well trained and experienced staff is key for the responsible use of nuclear energy. This is true in all areas including design, construction, operation, decommissioning, fuel cycle and waste management as well as radiation protection. Given the high average age of existing experts leading to a significant retirement induce a real risk of the loss of nuclear competencies in the coming years. Therefore the demand of hiring skilled employees is rising. The challenge of ensuring a sufficient number of qualified staff in the nuclear sector has been acknowledged widely among the different stakeholders, in particular the nuclear industry, national regulatory authorities and Technical Support Organisations (TSOs). Already the EURATOM Treaty refers explicitly to the obligation for the Commission to carry out training actions. Recently initiatives have been launched at EU level to facilitate and strengthen the efforts of national stakeholders. The European Nuclear Education Network (ENEN) Association aims at preservation and further development of expertise in the nuclear field by higher education and training. The goal of the European Nuclear Energy Leadership Academy (ENELA) is to educate future leaders in the nuclear field to ensure the further development of sustainable European nuclear energy solutions The European Nuclear Energy Forum (ENEF) is a platform operated by the European Commission for a broad discussion on the opportunities and risks of nuclear energy. The nuclear programs under investigation in the Joint Research Center (JRC) are increasingly contributing to Education and Training (E and T) initiatives, promoting a better cooperation between key players and universities as well as operators and regulatory bodies in order to mutually optimise their training programmes. Another objective is to increase

  18. The MEGAPIE Initiative

    International Nuclear Information System (INIS)

    Salvatores, M.; Bauer, G.S.; Heusener, G.

    2000-10-01

    MEGAPIE (Megawatt Pilot Experiment) is a joint initiative by Commissariat a l'Energie Atomique (CEA), France, Forschungszentrum Karlsruhe (FZK), Germany, and Paul Scherrer Institut (PSI), Switzerland, to design, build, operate and explore a liquid lead-bismuth spallation target for 1MW of beam power, taking advantage of the existing spallation neutron facility SINQ at PSI. Such a target based on an eutectic mixture with a melting point as low as 125 o C and a boiling point as high as 1670 o C is the preferred concept in several studies aiming at utilising accelerators to drive subcritical assemblies in order to transmute long lived nuclear waste into shorter lived isotopes in an effort to ease problems of long term storage and final disposal. MEGAPIE will be an essential step towards demonstrating the feasibility of the coupling of a high power accelerator, a spallation target and a subcritical assembly. It will specifically address one of the most critical issues, namely the behaviour of a liquid metal target under realistic operating conditions. As an intensely instrumented pilot experiment it will provide valuable data for benchmarking of frequently used computer codes and will allow to gain important experience in the safe handling of components that have been irradiated with PbBi. It will be installed at the ring cyclotron at PSI with 590 MeV proton energy and a continuous current of 1.8 mA. The basic concept of the MEGAPIE target as well as the definition of the project phases and of the supporting research and development activities at the participating laboratories are described in the present report

  19. Nursing Facility Initiative Annual Report

    Data.gov (United States)

    U.S. Department of Health & Human Services — This annual report summarizes impacts from the Initiative to Reduce Avoidable Hospitalizations among Nursing Facility Residents in 2014. This initiative is designed...

  20. National Take-Back Initiative

    Science.gov (United States)

    ... Disposal Information Drug and Chemical Information E-commerce Initiatives Federal Agencies & Related Links Federal Register Notices National ... Disposal Information Drug and Chemical Information E-commerce Initiatives Federal Agencies & Related Links Federal Register Notices National ...

  1. Citizen participation and citizen initiatives

    International Nuclear Information System (INIS)

    Matthoefer, H.

    1977-01-01

    Contents: Social conditions for citizen initiatives - technical change and employment - crisis behaviour - socio-psychological analysis of political planning; legitimation - presentation and criticism - conditions for citizen initiatives coming into being within the field of tension citizen : administration - legal problems of citizen initiatives - environmental protection in the energy discussion; participation; models. (HP) [de

  2. NLM Emergency Access Initiative: FAQs

    Science.gov (United States)

    Facebook Visit us on Twitter Visit us on Youtube Emergency Access Initiative Home | Journals | Books | Online Databases | FAQs Take Short Survey FAQ What is the Emergency Access Initiative? The Emergency Access Initiative (EAI) is a collaborative partnership between NLM and participating publishers to

  3. Initial Ada components evaluation

    Science.gov (United States)

    Moebes, Travis

    1989-01-01

    The SAIC has the responsibility for independent test and validation of the SSE. They have been using a mathematical functions library package implemented in Ada to test the SSE IV and V process. The library package consists of elementary mathematical functions and is both machine and accuracy independent. The SSE Ada components evaluation includes code complexity metrics based on Halstead's software science metrics and McCabe's measure of cyclomatic complexity. Halstead's metrics are based on the number of operators and operands on a logical unit of code and are compiled from the number of distinct operators, distinct operands, and total number of occurrences of operators and operands. These metrics give an indication of the physical size of a program in terms of operators and operands and are used diagnostically to point to potential problems. McCabe's Cyclomatic Complexity Metrics (CCM) are compiled from flow charts transformed to equivalent directed graphs. The CCM is a measure of the total number of linearly independent paths through the code's control structure. These metrics were computed for the Ada mathematical functions library using Software Automated Verification and Validation (SAVVAS), the SSE IV and V tool. A table with selected results was shown, indicating that most of these routines are of good quality. Thresholds for the Halstead measures indicate poor quality if the length metric exceeds 260 or difficulty is greater than 190. The McCabe CCM indicated a high quality of software products.

  4. German innovation initiative for nanotechnology

    Science.gov (United States)

    Rieke, Volker; Bachmann, Gerd

    2004-10-01

    In many areas of nanotechnology, Germany can count on a good knowledge basis due to its diverse activities in nanosciences. This knowledge basis, when paired with the production and sales structures needed for implementation and the internationally renowned German talent for system integration, should consequently lead to success in the marketplace. And this is exactly the field of application for the innovation initiative "Nanotechnologie erobert Märkte" (nanotechnology conquers markets) and for the new BMBF strategy in support of nanotechnology. Until now, aspects of nanotechnology have been advanced within the confines of their respective technical subject areas. However, the primary aim of incorporating them into an overall national strategy is to build on Germany's well-developed and internationally competitive research in science and technology to tap the potential of Germany's important industrial sectors for the application of nanotechnology through joint research projects (leading-edge innovations) that strategically target the value-added chain. This development is to be supported by government education policy to remedy a threatening shortage of skilled professionals. To realize that goal, forward-looking political policymaking must become oriented to a uniform concept of innovation, one that takes into consideration all facets of new technological advances that can contribute to a new culture of innovation in Germany. And that includes education and research policy as well as a climate that encourages and supports innovation in science, business and society.

  5. German innovation initiative for nanotechnology

    International Nuclear Information System (INIS)

    Rieke, Volker; Bachmann, Gerd

    2004-01-01

    In many areas of nanotechnology, Germany can count on a good knowledge basis due to its diverse activities in nanosciences. This knowledge basis, when paired with the production and sales structures needed for implementation and the internationally renowned German talent for system integration, should consequently lead to success in the marketplace. And this is exactly the field of application for the innovation initiative 'Nanotechnologie erobert Maerkte' (nanotechnology conquers markets) and for the new BMBF strategy in support of nanotechnology. Until now, aspects of nanotechnology have been advanced within the confines of their respective technical subject areas. However, the primary aim of incorporating them into an overall national strategy is to build on Germany's well-developed and internationally competitive research in science and technology to tap the potential of Germany's important industrial sectors for the application of nanotechnology through joint research projects (leading-edge innovations) that strategically target the value-added chain. This development is to be supported by government education policy to remedy a threatening shortage of skilled professionals. To realize that goal, forward-looking political policymaking must become oriented to a uniform concept of innovation, one that takes into consideration all facets of new technological advances that can contribute to a new culture of innovation in Germany. And that includes education and research policy as well as a climate that encourages and supports innovation in science, business and society

  6. Mitigation of greenhouse effect emissions from the running of new thermoelectric power plants in the Rio de Janeiro state; Mitigacao da emissao de gases de efeito estuda da entrada de novas UTEs no estado do Rio de Janeiro

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Joyce Maria Guimaraes; Oliveira, Luciano Basto [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia. Programa de Planejamento Energetico

    2004-07-01

    This article proposes and evaluates the mitigation alternatives for the greenhouse gases originated from the new thermal electric power plants in the Rio de Janeiro state. The alternatives are the reforesting with natural species from M ata Atlantica, reforesting for the Eucalipt vegetal coal production, plantation of oleaginous for production of bio diesel, and energy use of urban garbage. Also, an evaluation is performing on the mitigation potential of each alternative and the cost associated.

  7. Cable Diagnostic Focused Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Hartlein, R.A.; Hampton, R.N.

    2010-12-30

    This report summarizes an extensive effort made to understand how to effectively use the various diagnostic technologies to establish the condition of medium voltage underground cable circuits. These circuits make up an extensive portion of the electric delivery infrastructure in the United States. Much of this infrastructure is old and experiencing unacceptable failure rates. By deploying efficient diagnostic testing programs, electric utilities can replace or repair circuits that are about to fail, providing an optimal approach to improving electric system reliability. This is an intrinsically complex topic. Underground cable systems are not homogeneous. Cable circuits often contain multiple branches with different cable designs and a range of insulation materials. In addition, each insulation material ages differently as a function of time, temperature and operating environment. To complicate matters further, there are a wide variety of diagnostic technologies available for assessing the condition of cable circuits with a diversity of claims about the effectiveness of each approach. As a result, the benefits of deploying cable diagnostic testing programs have been difficult to establish, leading many utilities to avoid the their use altogether. This project was designed to help address these issues. The information provided is the result of a collaborative effort between Georgia Tech NEETRAC staff, Georgia Tech academic faculty, electric utility industry participants, as well as cable system diagnostic testing service providers and test equipment providers. Report topics include: •How cable systems age and fail, •The various technologies available for detecting potential failure sites, •The advantages and disadvantages of different diagnostic technologies, •Different approaches for utilities to employ cable system diagnostics. The primary deliverables of this project are this report, a Cable Diagnostic Handbook (a subset of this report) and an online

  8. Technology transfer from the space exploration initiative

    International Nuclear Information System (INIS)

    Buden, D.

    1991-01-01

    Space exploration has demonstrated that it stimulates the national economy by creating new and improved products, increased employment, and provides a stimulus to education. The exploration of the Moon and Mars under the Space Exploration Initiative has the potential of accelerating this stimulates to the economy. It is difficult to identify all of the concrete ways this will be accomplished. However, many areas can be identified. The space exploration building blocks of power, propulsion, spacecraft, robotics, rovers, mining and manufacturing, communications, navigation, habitats, life support and infrastructures are reviewed to identify possible technology areas. For example, better means for working in hazardous areas and handling hazardous waste are potential outcomes of this initiative. Methods to produce higher quality goods and improve America's competitiveness in manufacturing will undoubtedly evolve from the need to produce products that must last many years in the harsh environments of space and planetary surfaces. Some ideas for technology transfer are covered in this paper

  9. Microbial bio-fuels: a solution to carbon emissions and energy crisis.

    Science.gov (United States)

    Kumar, Arun; Kaushal, Sumit; Saraf, Shubhini A; Singh, Jay Shankar

    2018-06-01

    Increasing energy demand, limited fossil fuel resources and climate change have prompted development of alternative sustainable and economical fuel resources such as crop-based bio-ethanol and bio-diesel. However, there is concern over use of arable land that is used for food agriculture for creation of biofuel. Thus, there is a renewed interest in the use of microbes particularly microalgae for bio-fuel production. Microbes such as micro-algae and cyanobacteria that are used for biofuel production also produce other bioactive compounds under stressed conditions. Microbial agents used for biofuel production also produce bioactive compounds with antimicrobial, antiviral, anticoagulant, antioxidant, antifungal, anti-inflammatory and anticancer activity. Because of importance of such high-value compounds in aquaculture and bioremediation, and the potential to reduce carbon emissions and energy security, the biofuels produced by microbial biotechnology might substitute the crop-based bio-ethanol and bio-diesel production.

  10. Robustness of inflation to inhomogeneous initial conditions

    Energy Technology Data Exchange (ETDEWEB)

    Clough, Katy; Lim, Eugene A. [Theoretical Particle Physics and Cosmology Group, Physics Department, Kings College London, Strand, London WC2R 2LS (United Kingdom); DiNunno, Brandon S.; Fischler, Willy; Flauger, Raphael; Paban, Sonia, E-mail: katy.clough@kcl.ac.uk, E-mail: eugene.a.lim@gmail.com, E-mail: bsd86@physics.utexas.edu, E-mail: fischler@physics.utexas.edu, E-mail: flauger@physics.utexas.edu, E-mail: paban@physics.utexas.edu [Department of Physics, The University of Texas at Austin, Austin, TX, 78712 (United States)

    2017-09-01

    We consider the effects of inhomogeneous initial conditions in both the scalar field profile and the extrinsic curvature on different inflationary models. In particular, we compare the robustness of small field inflation to that of large field inflation, using numerical simulations with Einstein gravity in 3+1 dimensions. We find that small field inflation can fail in the presence of subdominant gradient energies, suggesting that it is much less robust to inhomogeneities than large field inflation, which withstands dominant gradient energies. However, we also show that small field inflation can be successful even if some regions of spacetime start out in the region of the potential that does not support inflation. In the large field case, we confirm previous results that inflation is robust if the inflaton occupies the inflationary part of the potential. Furthermore, we show that increasing initial scalar gradients will not form sufficiently massive inflation-ending black holes if the initial hypersurface is approximately flat. Finally, we consider the large field case with a varying extrinsic curvature K , such that some regions are initially collapsing. We find that this may again lead to local black holes, but overall the spacetime remains inflationary if the spacetime is open, which confirms previous theoretical studies.

  11. Florida Hydrogen Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Block, David L

    2013-06-30

    The Florida Hydrogen Initiative (FHI) was a research, development and demonstration hydrogen and fuel cell program. The FHI program objectives were to develop Florida?s hydrogen and fuel cell infrastructure and to assist DOE in its hydrogen and fuel cell activities The FHI program funded 12 RD&D projects as follows: Hydrogen Refueling Infrastructure and Rental Car Strategies -- L. Lines, Rollins College This project analyzes strategies for Florida's early stage adaptation of hydrogen-powered public transportation. In particular, the report investigates urban and statewide network of refueling stations and the feasibility of establishing a hydrogen rental-car fleet based in Orlando. Methanol Fuel Cell Vehicle Charging Station at Florida Atlantic University ? M. Fuchs, EnerFuel, Inc. The project objectives were to design, and demonstrate a 10 kWnet proton exchange membrane fuel cell stationary power plant operating on methanol, to achieve an electrical energy efficiency of 32% and to demonstrate transient response time of less than 3 milliseconds. Assessment of Public Understanding of the Hydrogen Economy Through Science Center Exhibits, J. Newman, Orlando Science Center The project objective was to design and build an interactive Science Center exhibit called: ?H2Now: the Great Hydrogen Xchange?. On-site Reformation of Diesel Fuel for Hydrogen Fueling Station Applications ? A. Raissi, Florida Solar Energy Center This project developed an on-demand forecourt hydrogen production technology by catalytically converting high-sulfur hydrocarbon fuels to an essentially sulfur-free gas. The removal of sulfur from reformate is critical since most catalysts used for the steam reformation have limited sulfur tolerance. Chemochromic Hydrogen Leak Detectors for Safety Monitoring ? N. Mohajeri and N. Muradov, Florida Solar Energy Center This project developed and demonstrated a cost-effective and highly selective chemochromic (visual) hydrogen leak detector for safety

  12. Violent Potentials

    DEFF Research Database (Denmark)

    Mikkelsen, Henrik Hvenegaard; Søgaard, Thomas Friis

    2015-01-01

    ” plays a critical role in relation to Bugkalot men’s construction of hegemonic masculinity and the sustaining of complex egalitarian relations. The Bugkalot have a notoriously violent history; until the late 1970s more than half of the adult men engaged in ritual killings. While most Bugkalot men has...... that can also be used in other contexts to understand how men construct hegemonic masculinity by strategically adopting the interspace of civility and violence.......This article explores the social significance of violence as potentiality and performance among former headhunters. Taking its outset in an ethnographic study of violence and masculinity among the Philippine people known as the Bugkalot, we explore how violence as “performed violent potentiality...

  13. Potential theory

    CERN Document Server

    Helms, Lester L

    2014-01-01

    Potential Theory presents a clear path from calculus to classical potential theory and beyond, with the aim of moving the reader into the area of mathematical research as quickly as possible. The subject matter is developed from first principles using only calculus. Commencing with the inverse square law for gravitational and electromagnetic forces and the divergence theorem, the author develops methods for constructing solutions of Laplace's equation on a region with prescribed values on the boundary of the region. The latter half of the book addresses more advanced material aimed at those with the background of a senior undergraduate or beginning graduate course in real analysis. Starting with solutions of the Dirichlet problem subject to mixed boundary conditions on the simplest of regions, methods of morphing such solutions onto solutions of Poisson's equation on more general regions are developed using diffeomorphisms and the Perron-Wiener-Brelot method, culminating in application to Brownian motion. In ...

  14. Initial conditions and entanglement sudden death

    International Nuclear Information System (INIS)

    Qian, Xiao-Feng; Eberly, J.H.

    2012-01-01

    We report results bearing on the behavior of non-local decoherence and its potential for being managed or even controlled. The decoherence process known as entanglement sudden death (ESD) can drive prepared entanglement to zero at the same time that local coherences and fidelity remain non-zero. For a generic ESD-susceptible Bell superposition state, we provide rules restricting the occurrence and timing of ESD, amounting to management tools over a continuous variation of initial conditions. These depend on only three parameters: initial purity, entanglement and excitation. Knowledge or control of initial phases is not needed. -- Highlights: ► We study the possibility of managing disentanglement through initial conditions. ► The initial parameters are the amount of entanglement, excitation, and purity. ► Entanglement sudden death (ESD) free and ESD susceptible phases are identified. ► ESD onset time is also presented in the ESD susceptible phase. ► Our results may guide experiments to prepare ESD free or delayed ESD states.

  15. Inflation with generalized initial conditions

    International Nuclear Information System (INIS)

    Albrecht, A.; Brandenberger, R.; Matzner, R.

    1987-01-01

    In many current models of the early Universe a scalar field phi which is only very weakly coupled to other quantum fields is used to generate inflation. In such models there are no forces which could thermalize the scalar field, and previous assumptions about its preinflation ''initial'' conditions must be abandoned. In this paper the onset of inflation is studied classically for more general initial conditions of the scalar field configuration. In particular, initial conditions with a nonvanishing spatial average of phi, with phi chosen at random in each initial horizon volume, and with random initial momenta are considered. We identify and discuss several mechanisms that can drive these more general initial conditions toward an inflationary state. The analysis is done in one spatial dimension

  16. EXPERIENCES WITH IDEA PROMOTING INITIATIVES

    DEFF Research Database (Denmark)

    Gish, Liv

    2011-01-01

    In new product development a central activity is to provide new ideas. Over the last decades experiences with stimulating employee creativity and establishing idea promoting initiatives have been made in industrial practice. Such initiatives are often labeled Idea Management – a research field...... with a growing interest. In this paper I examine three different idea promoting initiatives carried out in Grundfos, a leading pump manufacturer. In the analysis I address what understandings of idea work are inscribed in the initiatives and what role these initiatives play in the organization with respect...... understandings of idea work are inscribed in the idea promoting initiatives as they to some degree have to fit with the understandings embedded in practice in order to work....

  17. Potencial alelopático de Tropaeolum majus L. na germinação e crescimento inicial de plântulas de picão-preto Allelophaty potential of Tropaeolum majus L on picão-preto seeds germination and initial seedling growth

    Directory of Open Access Journals (Sweden)

    Anelise Samara Nazari Formagio

    2012-01-01

    Full Text Available Objetivou-se com este estudo avaliar o potencial alelopático de extratos metanólicos de folhas, flores e raízes de capuchinha (Tropaeolum majus L. sobre a germinação de sementes e o crescimento inicial de plântulas de picão-preto. O extrato metanólico com melhor potencial de inibição foi submetido a particionamento, resultando nas frações hexânica, clorofórmica, acetato de etila e hidrometanólica e posterior caracterização pelo espectro de absorção na região do infravermelho (IV. O efeito alelopático foi avaliado sobre as sementes de picão-preto, as quais foram distribuídas sobre papel germitest umedecido com 2mL dos extratos e mantidas em germinador do tipo B.O.D. regulado a temperatura de 25°C e luz branca constante, sendo que as sementes imersas diretamente em água constituíram o tratamento controle. A avaliação da qualidade da semente foi realizada pelos testes de germinação e vigor (primeira contagem e comprimento de raiz primária e de hipocótilo das plântulas, em delineamento inteiramente ao acaso. O potencial alelopático das folhas de capuchinha foi maior em relação às demais partes da planta sobre a germinação das sementes, comprimento de hipocótilo e de raiz das plântulas de picão-preto. Estes efeitos podem estar associados à presença de grupos químicos polares, pois à medida que se aumentou a polaridade dos solventes detectou-se maior efeito inibitório sobre a germinação e o crescimento inicial de plântulas de picão-preto.This research aimed to evaluate the metanolic extracts allelopathic potential from leaves, flowers and roots of capuchinha (Tropaeolum majus L. on picão-preto seeds germination and initial seedling growth. The best inhibitor metanolic extract was fractioned, in hexanic, cloroformic, etil acetate and hidrometanolic fractions and it was characterized through absorption spectrum using mid-infrared. To evaluate the allelopathic effect of metanolic extracts and the

  18. Initiation into Adolescent Marijuana Use.

    Science.gov (United States)

    Brook, Judith S.; And Others

    1980-01-01

    This longitudinal study examined the relationship of three domains (personality/attitudinal orientations, peer relationships, and family socialization factors) with initiation into adolescent marihuana use. (Author/DB)

  19. EC initiatives promise mixed blessings: a Belgian utility perspective

    International Nuclear Information System (INIS)

    Fraix, J.

    1992-01-01

    The potential effects on nuclear power of European Community initiatives are analysed from the viewpoint of a Belgian utility. The initiatives fall under the three broad headings of: East-West co-operation; completing the internal market; and carbon dioxide emission. (Author)

  20. Open Geodata Initiative for Romania

    Science.gov (United States)

    Craciunescu, Vasile; Iosifescu, Ionut; Ilie, Codrina Maria; Gaitanaru, Dragos; Radu Gogu, Constantin; Hurni, Lorenz

    2013-04-01

    The concept of open data access is a very important topic nowadays. The concept assumes that all data collected or generated by public sector bodies (excepting personal data and data protected under existing privacy protection or accessibility rules) is made publicly accessible in commonly-used, machine-readable formats and can be re-used for any purpose, commercial or non-commercial. Governmental agencies are considered to be the most significant data owners and providers in modern societies. The sheer volume and wealth of this data makes apparent the potential benefits of reusing, combining, and processing governmental data. Even though metadata (information about the data) is sometimes published, administrations typically express reluctance to making their data available, for various reasons, cultural, political, legal, institutional and technical. The governmental spatial information (also called geospatial data, georeferenced data or geodata) producers in Romania are no exception -with the additional situation that even metadata is not usually available. Starting from 2013 a joint program between a Swiss partner (The Swiss Federal Institute of Technology ETH- Zurich - Institute of Cartography and Geoinformation) and a Romanian partner (Technical University of Civil Engineering - UTCB) is developed in order to establish a new approach on the open geodata topic. The main objective of the project GEOIDEA.RO (GEodata Openness Initiative for Development and Economic Advancement in ROmania) is to improve the scientific basis for open geodata model adoption in Romania. Is our believe that publishing government geodata in Romania over the Internet,under an open license and in a reusable format can strengthen citizen engagement and yield new innovative businesses, bringing substantial social and economic gains.

  1. SCC Initiation Testing of Alloy 600 in High Temperature Water

    Science.gov (United States)

    Etien, Robert A.; Richey, Edward; Morton, David S.; Eager, Julie

    Stress corrosion cracking (SCC) initiation tests have been conducted on Alloy 600 at temperatures from 304 to 367°C. Tests were conducted with in-situ monitored smooth tensile specimens under a constant load in hydrogenated environments. A reversing direct current electric potential drop (EPD) system was used for all of the tests to detect SCC initiation. Tests were conducted to examine the effects of stress (and strain), coolant hydrogen, and temperature on SCC initiation time. The thermal activation energy of SCC initiation was measured as 103 ± 18 kJ/mol in hydrogenated water, which is similar to the thermal activation energy for SCC growth. Results suggest that the fundamental mechanical parameter which controls SCC initiation is plastic strain not stress. SCC initiation was shown to have a different sensitivity than SCC growth to dissolved hydrogen level. Specifically, SCC initiation time appears to be relatively insensitive to hydrogen level in the nickel stability region.

  2. Assessing offshore wind potential

    International Nuclear Information System (INIS)

    Adelaja, Adesoji; McKeown, Charles; Calnin, Benjamin; Hailu, Yohannes

    2012-01-01

    Quantifying wind potential is a pivotal initial step in developing and articulating a state’s policies and strategies for offshore wind industry development. This is particularly important in the Great Lakes States where lessons from other offshore environments are not directly applicable. This paper presents the framework developed for conducting a preliminary assessment of offshore wind potential. Information on lake bathymetry and wind resources were combined in simulating alternative scenarios of technically feasible turbine construction depths and distance concerns by stakeholders. These yielded estimates of developable offshore wind areas and potential power generation. While concerns about the visibility of turbines from shore reduce the power that can be generated, engineering solutions that increase the depths at which turbines can be sited increase such potential power output. This paper discusses the costs associated with technical limitations on depth and the social costs related to public sentiments about distance from the shoreline, as well as the possible tradeoffs. The results point to a very large untapped energy resource in the Michigan’s Great Lakes, large enough to prompt policy action from the state government. - Highlights: ▶ We build a theoretical framework for modeling offshore wind power production. ▶ Illustration of the impact of technology and social limitations on offshore wind energy development. ▶ Geospatial modeling of the offshore wind potential of the Great Lakes.

  3. Violent potentials

    DEFF Research Database (Denmark)

    Mikkelsen, Henrik Hvenegaard; Friis Søgaard, Thomas

    2016-01-01

    as ‘performed violent potentiality’ plays a critical role in relation to Bugkalot men’s construction of hegemonic masculinity and the sustaining of complex egalitarian relations. The Bugkalot have a notoriously violent history; until the late 1970s more than half of the adult men engaged in ritual killings...... provide general insights that can also be used in other contexts to understand how men construct hegemonic masculinity by strategically adopting the interspace of civility and violence.......This article explores the social significance of violence as potentiality and performance among former headhunters engaged in ritual killings. Taking its outset in an ethnographic study of violence and masculinity among the Philippine people known as the Bugkalot, we explore how violence...

  4. Career Technical Education Pathways Initiative

    Science.gov (United States)

    California Community Colleges, Chancellor's Office, 2013

    2013-01-01

    California's education system--the largest in the United States--is an essential resource for ensuring strong economic growth in the state. The Career Technical Education Pathways Initiative (referred to as the Initiative in this report), which became law in 2005, brings together community colleges, K-12 school districts, employers, organized…

  5. The metabolomics standards initiative (MSI)

    NARCIS (Netherlands)

    Fiehn, O.; Robertson, D.; Griffin, J.; Werf, M. van der; Nikolau, B.; Morrison, N.; Sumner, L.W.; Goodacre, R.; Hardy, N.W.; Taylor, C.; Fostel, J.; Kristal, B.; Kaddurah-Daouk, R.; Mendes, P.; Ommen, B. van; Lindon, J.C.; Sansone, S.-A.

    2007-01-01

    In 2005, the Metabolomics Standards Initiative has been formed. An outline and general introduction is provided to inform about the history, structure, working plan and intentions of this initiative. Comments on any of the suggested minimal reporting standards are welcome to be sent to the open

  6. Behavioral Initiatives in Broad Perspective.

    Science.gov (United States)

    California Univ., Los Angeles. Center for Mental Health in Schools.

    This booklet is a technical assistance sampler addressing the issues of student misbehavior, discipline problems, and behavioral initiatives. The term behavioral initiative is defined, disciplining children with disabilities is discussed, and a cautionary note concerning ignoring students' reasons for misbehavior is presented. A brief entitled…

  7. Local initiative extrapolated to nation

    DEFF Research Database (Denmark)

    Wittchen, Kim Bjarne; Kragh, Jesper; Brøgger, Morten

    In the municipality of Sønderborg, in the southern part of Jutland, there is a shining example initiated in 2007, ProjectZero, of a local initiative that have resulted in extensive energy savings in residential buildings and at the same time created local workplaces. The intension with the pilot...

  8. Northern Eurasia Future Initiative (NEFI)

    DEFF Research Database (Denmark)

    Groisman, Pavel; Shugart, Herman; Kicklighter, David

    2017-01-01

    . The Northern Eurasia Future Initiative (NEFI) has been designed as an essential continuation of the Northern Eurasia Earth Science Partnership Initiative (NEESPI), which was launched in 2004. NEESPI sought to elucidate all aspects of ongoing environmental change, to inform societies and, thus, to better...

  9. Comprehensive School Safety Initiative Report

    Science.gov (United States)

    National Institute of Justice, 2014

    2014-01-01

    The National Institute of Justice (NIJ) developed the Comprehensive School Safety Initiative in consultation with federal partners and Congress. It is a research-focused initiative designed to increase the safety of schools nationwide through the development of knowledge regarding the most effective and sustainable school safety interventions and…

  10. Initial conditions for chaotic inflation

    International Nuclear Information System (INIS)

    Brandenberger, R.; Kung, J.; Feldman, H.

    1991-01-01

    In contrast to many other inflationary Universe models, chaotic inflation does not depend on fine tuning initial conditions. Within the context of linear perturbation theory, it is shown that chaotic inflation is stable towards both metric and matter perturbations. Neglecting gravitational perturbations, it is shown that chaotic inflation is an attractor in initial condition space. (orig.)

  11. Self-initiated expatriate academics

    DEFF Research Database (Denmark)

    Selmer, Jan; Lauring, Jakob

    2013-01-01

    In this chapter we examine self-initiated expatriate academics. Universities are to an increasing extent looking for talent beyond national boundaries. Accordingly, self-initiated expatriate academics represent a fast growing group of highly educated professionals who gain employment abroad...

  12. Correlates of sexual initiation among European adolescents

    Science.gov (United States)

    Carli, Vladimir; Hadlaczky, Gergö; Sarchiapone, Marco; Apter, Alan; Balazs, Judit; Banzer, Raphaela; Bobes, Julio; Brunner, Romuald; Cosman, Doina; Farkas, Luca; Haring, Christian; Hoven, Christina W.; Kaess, Michael; Kahn, Jean Pierre; McMahon, Elaine; Postuvan, Vita; Sisask, Merike; Värnik, Airi; Zadravec Sedivy, Nusa; Wasserman, Danuta

    2018-01-01

    initiation among boys. Significant predictors included also being bullied, fighting, truancy, and low parental involvement. Conclusions Adolescent sexual behaviours are related to non-sexual risk behaviours, psychological difficulties and contextual vulnerabilities. While gateway effects explain some associations, a comprehensive model is needed to understand adolescent sexual behaviours, their physical, mental, and social health outcomes, and their potential positive effects on wellbeing. Tailored interventions may need to consider younger girls as a particularly vulnerable group in view of a strong association between non-sexual and sexual behaviors. PMID:29420612

  13. Correlates of sexual initiation among European adolescents.

    Directory of Open Access Journals (Sweden)

    Pietro Gambadauro

    Full Text Available Sexuality is a physiological component of adolescent development, though early initiation is associated with reproductive health risk. This study aimed at identifying correlates and predictors of sexual initiation in a large multinational cohort of European adolescents.A questionnaire addressing socio-demographics, behaviours, mental health and sexual activity, was delivered to 11,110 adolescents recruited from 168 randomly selected schools in 10 European countries between 2009 and 2011. A follow-up questionnaire was delivered after 12 months. The longitudinal association of baseline risk behaviors, psychological attributes and contextual vulnerabilities, with sexual initiation during follow-up was evaluated through simple and multivariable age/sex stratified logistic regression. Multinomial logistic regression measured the association between predictors and sexual initiation with or without coexisting reproductive risk factors, such as multiple partners or infrequent condom use.Baseline sexual experience was reported by 19.2% of 10,757 respondents (median age 15; IQR 14-15; females 59.6%. This was significantly more frequent among pupils older than 15 (41% and males (20.8%. Of 7,111 pupils without previous experience who were available at follow-up (response rate 81.8%, 17% reported sexual initiation, without differences between females and males. Baseline smoking (age/sex adjusted odds ratio [aOR] 3.63, alcohol use (aOR 2.95, illegal drugs use (aOR 2.72, and poor sleep (aOR 1.71 predicted sexual initiation. Stratified analyses showed a particularly strong association in case of younger and female pupils, and, among girls, when initiation was reported together with multiple partners and/or infrequent condom use. Externalizing (i.e. conduct and hyperactivity symptoms independently predicted sexual initiation. Internalizing difficulties (i.e. emotional and peer problems were negatively associated with early and risky sexual initiation among boys

  14. Status of jatropha cultivation for biodiesel production in Pakistan

    International Nuclear Information System (INIS)

    Khan, N.A.; Usmani, J.N.

    2010-01-01

    Pakistan is highly dependent on imported fuels. Sustainable production of biodiesel presents an opportunity to reduce reliance on imported oil, save foreign-exchange reserves, reduce poverty and unemployment, stimulate rural development in areas with acute poverty and enhance access to renewable commercial energy. We are an agriculture-based economy; therefore, production of Bio diesel by utilizing agro-base cultivation will strengthen our agricultural sector and empower the farmers. Moreover, the country has immense potential to attain energy-security through domestic cultivation and processing of bio fuel crops. Some details of the processing plant and manufacturing are also given. This paper describes and delineates the present status of Jatropha cultivation in Pakistan. An attempt is made to project the future of bio diesel, through Jatropha seeds and simultaneous efforts to cultivate other bio diesel- producing seeds to make its cost as low as possible. This paper can also be taken as a base to predict the minimum time required to produce 5-10% replacement of mineral diesel by biodiesel. (author)

  15. Initial Assessment of Whiplash Patients

    Directory of Open Access Journals (Sweden)

    R Gunzburg

    2003-01-01

    Full Text Available The article looks at how for severe trauma, the outcome of treatment depends on the initial medical care. This has now also been accepted for whiplash associated disorders, underlining the importance of a proper initial assessment. Once major injury has been excluded and the diagnosis of whiplash associated disorder has been established, the initial treatment of whiplash in the emergency room can be started. The four key points to remember are described, including reassuring the patient about evolution, no soft collar, nonsteroidal anti-inflammatory drugs and early mobilisation.

  16. Canada's family violence initiative: partnerships

    Directory of Open Access Journals (Sweden)

    Elaine Scott

    1994-01-01

    Full Text Available Under Canada's four-year, $136 million Family Violence Initiative, the federal government is calling upon all Canadians to work in partnerships towards the elimination of family violence - child abuse, violence against women, and elder (senior abuse. Family violence is a complex problem and requires the efforts of all Canadians to resolve it. One of the key themes of the Initiative - a multidisciplinary approach to the problem of family violence - is reflected in the selection and development of projects. Activities funded by the seven federal departments and agencies involved in the Initiative emphasize partnerships with the professional, voluntary, corporate, non-government and government sectors.

  17. Learning from the Ilulissat Initiative

    DEFF Research Database (Denmark)

    Rahbek-Clemmensen, Jon; Thomasen, Gry

    In May 2018, ten years will have passed since the representatives from the five Arctic coastal states (Canada, Denmark, Norway, Russia) and the Home Rule government of Greenland met in Ilulissat. Learning from the Ilulissat Initiative examines how the initiative came about, and how it has affected...... strong economic interests in maintaining peaceful Arctic relations. Northern forums therefore give policymakers a rare opportunity to meet, communicate, and influence a key region. The Ilulissat meeting was the result of a joint Danish‒Greenlandic initiative and is often hailed as one of the most...

  18. The Luxembourg Space Resources Initiative

    Science.gov (United States)

    Link, M.

    2017-09-01

    This keynote talk by M. Link from the Directorate of ICT and Space Affairs, Ministry of the Economy, The Government of the Grand Duchy of Luxembourg, will provide an overview of Luxembourg's ins-space resource utilization initiative.

  19. Integrated landscape initiatives in Europe

    DEFF Research Database (Denmark)

    García-Martín, María; Bieling, Claudia; Hart, Abigail

    2016-01-01

    Landscapes are linked to human well-being in a multitude of ways, some of which are challenged by global market forces and traditional management approaches. In response to this situation there has been a rise in local initiatives to sustain the values of landscape. The aim of this paper is to pr......Landscapes are linked to human well-being in a multitude of ways, some of which are challenged by global market forces and traditional management approaches. In response to this situation there has been a rise in local initiatives to sustain the values of landscape. The aim of this paper...... searches and canvassing of European umbrella organisations; followed by an online survey of representatives from the identified initiatives (n??=??71). Our results show that the most relevant characteristics of integrated landscape initiatives in Europe are: a holistic approach to landscape management...

  20. FY 10 Multifamily Initial Endorsements

    Data.gov (United States)

    Department of Housing and Urban Development — In FY 2010, HUD's Multifamily's 18 Hubs initially endorsed 1011 loans totaling $11.3 billion and providing 170,672 units/ beds. FY 10's $11.3 billion is the highest...

  1. Smart roadside initiative : user manual.

    Science.gov (United States)

    2015-09-01

    This document provides the user instructions for the Smart Roadside Initiative (SRI) applications including mobile and web-based SRI applications. These applications include smartphone-enabled information exchange and notification, and software compo...

  2. Smart roadside initiative : final report.

    Science.gov (United States)

    2015-09-01

    This is the Final Report for the Smart Roadside Initiative (SRI) prototype system deployment project. The SRI prototype was implemented at weigh stations in Grass Lake, Michigan and West Friendship, Maryland. The prototype was developed to integrate ...

  3. Global Peace Operations Initiative (GPOI)

    National Research Council Canada - National Science Library

    Kim-Mitchell, Elena

    2005-01-01

    .... In terms of manpower, the initiative aims at deploying 75,000 peace support operations (PSO) troops worldwide over the next 5 years, primarily to Africa, but also to Latin America, Europe, and Asia...

  4. Canada's family violence initiative: partnerships

    OpenAIRE

    Scott,Elaine

    1994-01-01

    Under Canada's four-year, $136 million Family Violence Initiative, the federal government is calling upon all Canadians to work in partnerships towards the elimination of family violence - child abuse, violence against women, and elder (senior) abuse. Family violence is a complex problem and requires the efforts of all Canadians to resolve it. One of the key themes of the Initiative - a multidisciplinary approach to the problem of family violence - is reflected in the selection and developmen...

  5. Student initiative: A conceptual analysis

    OpenAIRE

    Polovina Nada

    2014-01-01

    In the description and scientific consideration of the attitude of children and youth towards their education and development, the concept of student initiative has been gaining ground lately, and it is hence the subject of analysis in this paper. The analysis is important because of the discrepancy between the increased efforts of the key educational policy holders to promote the idea about the importance of the development of student initiative and rare a...

  6. Teachers’ perceptions of their own initiative: Collective initiative vs. personal initiative

    Directory of Open Access Journals (Sweden)

    Džinović Vladimir

    2013-01-01

    Full Text Available Current trends in education demand from teachers to exhibit proactive behaviour and assume responsibility for the implementation of changes in school practice. In that sense, it is important to study how teachers perceive their own initiative and to gain insight into the activities where such initiative is demonstrated. This study has been conceived as a mixed-methods research. The qualitative study implied forming four focus groups with subject teachers and class teachers (N=38, while the quantitative study entailed surveying 1441 teachers in forty primary schools in Serbia using the questionnaire constructed based on qualitative data. Data from focus groups were processed by qualitative thematic analysis, while the questionnaire data were processed by principal component analysis and univariate analysis of variance. The findings of the study have shown that teachers mostly demonstrate initiative through co­operative activities that include planning of joint teaching as well as conducting joint projects within school and with the local community actors. Teachers are least ready to demonstrate personal initiative and the initiative aimed at accomplishing considerable changes in school work. The concluding part includes the recommendations for encouraging teachers’ personal initiative and building organizational culture that would support such initiative. [Projekat Ministarstva nauke Republike Srbije, br. br. 47008: Unapređivanje kvaliteta i dostupnosti obrazovanja u procesima modernizacije Srbije i br. 179034: Od podsticanja inicijative, saradnje i stvaralaštva u obrazovanju do novih uloga i identiteta u društvu

  7. Harmonic Detection at Initialization With Kalman Filter

    DEFF Research Database (Denmark)

    Hussain, Dil Muhammad Akbar; Imran, Raja Muhammad; Shoro, Ghulam Mustafa

    2014-01-01

    Most power electronic equipment these days generate harmonic disturbances, these devices hold nonlinear voltage/current characteristic. The harmonics generated can potentially be harmful to the consumer supply. Typically, filters are integrated at the power source or utility location to filter out...... the affect of harmonics on the supply. For the detection of these harmonics various techniques are available and one of that technique is the Kalman filter. In this paper we investigate that what are the consequences when harmonic detection system based on Kalman Filtering is initialized...

  8. Initial state radiation experiment at MAMI

    Energy Technology Data Exchange (ETDEWEB)

    Mihovilovič, M.; Merkel, H. [Institut für Kernphysik, Johannes Gutenberg-Universität Mainz, Johann-Joachim-Becher-Weg 45, 55128 Mainz (Germany); Collaboration: A1-Collaboration

    2013-11-07

    In an attempt to contribute further insight into the discrepancy between the Lamb shift and elastic scattering determinations of the proton charge radius, a new experiment at MAMI is underway, aimed at measuring proton form-factors at very low momentum transfers by using a new technique based on initial state radiation. This paper reports on first findings of the pilot measurement performed in 2010, whose main goal was to check the feasibility of the proposed experiment and to recognize and overcome potential obstacles before running the full experiment in 2013.

  9. Characteristics of patients initiating raloxifene compared to those initiating bisphosphonates

    Directory of Open Access Journals (Sweden)

    Wang Sara

    2008-12-01

    Full Text Available Abstract Background Both raloxifene and bisphosphonates are indicated for the prevention and treatment of postmenopausal osteoporosis, however these medications have different efficacy and safety profiles. It is plausible that physicians would prescribe these agents to optimize the benefit/risk profile for individual patients. The objective of this study was to compare demographic and clinical characteristics of patients initiating raloxifene with those of patients initiating bisphosphonates for the prevention and treatment of osteoporosis. Methods This study was conducted using a retrospective cohort design. Female beneficiaries (45 years and older with at least one claim for raloxifene or a bisphosphonate in 2003 through 2005 and continuous enrollment in the previous 12 months and subsequent 6 months were identified using a collection of large national commercial, Medicare supplemental, and Medicaid administrative claims databases (MarketScan®. Patients were divided into two cohorts, a combined commercial/Medicare cohort and a Medicaid cohort. Within each cohort, characteristics (demographic, clinical, and resource utilization of patients initiating raloxifene were compared to those of patients initiating bisphosphonate therapy. Group comparisons were made using chi-square tests for proportions of categorical measures and Wilcoxon rank-sum tests for continuous variables. Logistic regression was used to simultaneously examine factors independently associated with initiation of raloxifene versus a bisphosphonate. Results Within both the commercial/Medicare and Medicaid cohorts, raloxifene patients were younger, had fewer comorbid conditions, and fewer pre-existing fractures than bisphosphonate patients. Raloxifene patients in both cohorts were less likely to have had a bone mineral density (BMD screening in the previous year than were bisphosphonate patients, and were also more likely to have used estrogen or estrogen/progestin therapy in the

  10. Alberta industrial synergy CO2 programs initiative

    International Nuclear Information System (INIS)

    Yildirim, E.

    1998-01-01

    The various industrial sectors within Alberta produce about 350,000 tonnes of CO 2 per day. This presentation was concerned with how this large volume and high concentration of CO 2 can be used in industrial and agricultural applications, because every tonne of CO 2 used for such purposes is a tonne that does not end up in the atmosphere. There is a good potential for an industrial synergy between the producers and users of CO 2 . The Alberta Industrial Synergy CO 2 Programs Initiative was established to ultimately achieve a balance between the producers of CO 2 and the users of CO 2 by creating ways to use the massive quantities of CO 2 produced by Alberta's hydrocarbon-based economy. The Alberta CO 2 Research Steering Committee was created to initiate and support CO 2 programs such as: (1) CO 2 use in enhanced oil recovery, (2) creation of a CO 2 production inventory, (3) survey of CO 2 users and potential users, (4) investigation of process issues such as power generation, oil sands and cement manufacturing, and (5) biofixation by plants, (6) other disposal options (e.g. in depleted oil and gas reservoirs, in aquifers, in tailings ponds, in coal beds). The single most important challenge was identified as 'rationalizing the formation of the necessary infrastructure'. Failing to do that will greatly impede efforts directed towards CO 2 utilization

  11. Driftless Area Initiative Biomass Energy Project

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Angie [Northeast Iowa Resource Conservation & Development, Inc., Postville, IA (United States); Bertjens, Steve [Natural Resources Conservation Service, Madison, WI (United States); Lieurance, Mike [Northeast Iowa Resource Conservation & Development, Inc., Postville, IA (United States); Berguson, Bill [Univ. of Minnesota, Minneapolis, MN (United States). Natural Resources Research Inst.; Buchman, Dan [Univ. of Minnesota, Minneapolis, MN (United States). Natural Resources Research Inst.

    2012-12-31

    The Driftless Area Initiative Biomass Energy Project evaluated the potential for biomass energy production and utilization throughout the Driftless Region of Illinois, Iowa, Minnesota and Wisconsin. The research and demonstration aspect of the project specifically focused on biomass energy feedstock availability and production potential in the region, as well as utilization potential of biomass feedstocks for heat, electrical energy production, or combined heat and power operations. The Driftless Region was evaluated because the topography of the area offers more acres of marginal soils on steep slopes, wooded areas, and riparian corridors than the surrounding “Corn Belt”. These regional land characteristics were identified as potentially providing opportunity for biomass feedstock production that could compete with traditional agriculture commodity crops economically. The project researched establishment methods and costs for growing switchgrass on marginal agricultural lands to determine the economic and quantitative feasibility of switchgrass production for biomass energy purposes. The project was successful in identifying the best management and establishment practices for switchgrass in the Driftless Area, but also demonstrated that simple economic payback versus commodity crops could not be achieved at the time of the research. The project also analyzed the availability of woody biomass and production potential for growing woody biomass for large scale biomass energy production in the Driftless Area. Analysis determined that significant resources exist, but costs to harvest and deliver to the site were roughly 60% greater than that of natural gas at the time of the study. The project contributed significantly to identifying both production potential of biomass energy crops and existing feedstock availability in the Driftless Area. The project also analyzed the economic feasibility of dedicated energy crops in the Driftless Area. High commodity crop prices

  12. The sustainable wood production initiative.

    Science.gov (United States)

    Robert. Deal

    2004-01-01

    To address concerns about sustainable forestry in the region, the Focused Science Delivery Program is sponsoring a three year Sustainable Wood Production Initiative. The Pacific Northwest is one of the world's major timber producing regions, and the ability of this region to produce wood on a sustained yield basis is widely recognized. Concerns relating to the...

  13. Intelligent vehicle initiative : business plan

    Science.gov (United States)

    1997-11-01

    The U.S. Department of Transportation (USDOT) is embarking on a new program called the Intelligent Vehicle Initiative (IVI). The USDOT intends to jointly define the program plan and conduct the IVI in cooperation with the motor vehicle, trucking, and...

  14. Nuclear materials facility safety initiative

    International Nuclear Information System (INIS)

    Peddicord, K.L.; Nelson, P.; Roundhill, M.; Jardine, L.J.; Lazarev, L.; Moshkov, M.; Khromov, V.V.; Kruchkov, E.; Bolyatko, V.; Kazanskij, Yu.; Vorobeva, I.; Lash, T.R.; Newton, D.; Harris, B.

    2000-01-01

    Safety in any facility in the nuclear fuel cycle is a fundamental goal. However, it is recognized that, for example, should an accident occur in either the U.S. or Russia, the results could seriously delay joint activities to store and disposition weapons fissile materials in both countries. To address this, plans are underway jointly to develop a nuclear materials facility safety initiative. The focus of the initiative would be to share expertise which would lead in improvements in safety and safe practices in the nuclear fuel cycle.The program has two components. The first is a lab-to-lab initiative. The second involves university-to-university collaboration.The lab-to-lab and university-to-university programs will contribute to increased safety in facilities dealing with nuclear materials and related processes. These programs will support important bilateral initiatives, develop the next generation of scientists and engineers which will deal with these challenges, and foster the development of a safety culture

  15. Initial heating in cold cars

    NARCIS (Netherlands)

    Daanen, H.A.M.; Teunissen, L.P.J.; Hoogh, I.M. de

    2012-01-01

    During the initial minutes after entering a cold car, people feel uncomfortably cold. Six different warming systems were investigated in a small car in order to find out how to improve the feeling of comfort using 16 volunteers. The methods were: no additional warming next to a standard heating

  16. Does the cerebellum initiate movement?

    Science.gov (United States)

    Thach, W T

    2014-02-01

    Opinion is divided on what the exact function of the cerebellum is. Experiments are summarized that support the following views: (1) the cerebellum is a combiner of multiple movement factors; (2) it contains anatomically fixed permanent focal representation of individual body parts (muscles and segments) and movement modes (e.g., vestibular driven vs. cognitive driven); (3) it contains flexible changing representations/memory of physical properties of the body parts including muscle strength, segment inertia, joint viscosity, and segmental interaction torques (dynamics); (4) it contains mechanisms for learning and storage of the properties in item no. 3 through trial-and-error practice; (5) it provides for linkage of body parts, motor modes, and motordynamics via the parallel fiber system; (6) it combines and integrates the many factors so as to initiate coordinated movements of the many body parts; (7) it is thus enabled to play the unique role of initiating coordinated movements; and (8) this unique causative role is evidenced by the fact that: (a) electrical stimulation of the cerebellum can initiate compound coordinated movements; (b) in naturally initiated compound movements, cerebellar discharge precedes that in downstream target structures such as motor cerebral cortex; and (c) cerebellar ablation abolishes the natural production of compound movements in the awake alert individuals.

  17. Light-initiated detonation systems

    Science.gov (United States)

    Cooper, Stafford S.; Malone, Philip G.; Bartholomew, Stephen W.; Necker, William J.

    1986-09-01

    Numerous light sources could be employed in detonation systems, but lasers have the most efficient coupling to optical fibers and can generate energetic light pulses required for detonation. Flash lamp-pumped, solid state lasers are presently the most useful light source for explosive initiation. Laser diodes in current production cannot generate enough energy for practical applications. The most useful optical fiber for blast line application is a step index fiber with a large core-to-cladding ratio. The large core minimizes energy losses due to misalignment core of fibers in connectors. Couplers that involve mechanically crimped connectors and cleaved fibers, rather than the epoxy-cemented connectors with polished fibers, provide superior energy transmission due to the reduced carbonization at the fiber end. Detonators for optical initiation systems are similar in basic construction to those employed in electrical initiation systems. Explosive and pyrotechnic charges can also be similar. Either primary or secondary explosives can be initiated in present laser-based systems. Two laser detonation systems are presently accessible; a multiple-shot laser with a single-shot, single fiber system designed for use with detonators containing primary explosives. Additional research related to development of low-energy, photoreactive detonators, continuity checking techniques and improved connectors and fibers can produce significant improvements in presently fielded systems.

  18. Big Data Initiatives for Agroecosystems

    Science.gov (United States)

    NAL has developed a workspace for research groups associated with the i5k initiative, which aims to sequence the genomes of all insesct species known to be important to worldwide agriculture, food safety, medicine, and energy production; all those used as models in biology; the most abundant in worl...

  19. Smoking Initiation: Peers and Personality

    NARCIS (Netherlands)

    C-S. Hsieh (Chih-Sheng); J.L.W. van Kippersluis (Hans)

    2016-01-01

    textabstractSocial interactions are widely recognized to play an important role in smoking initiation among adolescents. In this paper we hypothesize that individual with `stronger' personalities (i.e. emotionally stable, conscientious individuals) are better able to resist peer pressure in the

  20. Vacuum type D initial data

    Science.gov (United States)

    García-Parrado Gómez-Lobo, Alfonso

    2016-09-01

    A vacuum type D initial data set is a vacuum initial data set of the Einstein field equations whose data development contains a region where the space–time is of Petrov type D. In this paper we give a systematic characterisation of a vacuum type D initial data set. By systematic we mean that the only quantities involved are those appearing in the vacuum constraints, namely the first fundamental form (Riemannian metric) and the second fundamental form. Our characterisation is a set of conditions consisting of the vacuum constraints and some additional differential equations for the first and second fundamental forms These conditions can be regarded as a system of partial differential equations on a Riemannian manifold and the solutions of the system contain all possible regular vacuum type D initial data sets. As an application we particularise our conditions for the case of vacuum data whose data development is a subset of the Kerr solution. This has applications in the formulation of the nonlinear stability problem of the Kerr black hole.

  1. Initial drug resistance in India

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Initial drug resistance in India. There is gradual increase in primary MDR all over India : Pondi= Pondicherry 1985; Bangalore =1986; Jaipur = 1991; Jaipur =2000. Overall the MDR is less than 3% (TRC studies).

  2. Parenting and Adolescents' Sexual Initiation

    Science.gov (United States)

    Longmore, Monica A.; Eng, Abbey L.; Giordano, Peggy C.; Manning, Wendy D.

    2009-01-01

    This study draws on social control and social learning theories to examine the role of dating-specific attitudes and practices as predictors of adolescents' sexual initiation. We include attention to the adolescent's reaction to control attempts as a further means of assessing family dynamics (i.e., frequency of dating disagreements). The study…

  3. Russian Initiatives in Internet Governance

    Directory of Open Access Journals (Sweden)

    Sergey Sergeevich Shirin

    2014-01-01

    Full Text Available The article is devoted to the research of Russian initiatives concerning its participation in international system of Internet governance. In the research, conceptual and theoretic basis for participation of state governments in Internet governance is given, academic discourse of this issue is assessed, the review of main Russian initiatives made from 2005 (since the second stage of the World Summit on Information Society till the present day is carried out. The conclusion is made that the most successful Internet governance initiative of Russia is the implementation of cyrillic top level domains. Much less successful are Russian attempts to reconstruct existing organizational structure of Internet governance. Russian policy is assessed as a policy of preferring loud statements and PR rather than real influence on development of Internet technologies. Russia consideres Internet as political resource and tries to increase its influence on decision making process on a political, not operational level of Internet governance. The author states that federal government of the United States of America has fully lost the control on the domain name systems. These functions are going to be given to the private sector, while ICANN, which was established according to the Memorandum of Understanding/Joint Project Agreement with U.S. Department of Commerce, is becoming a truly independent international organization. Considering this, the author comes to the conclusion that political transformations for the sake of Russia are already made. He also forecast that next initiatives of Russia will be directed to the segmentation of the Internet.

  4. Feasibility Study of Economics and Performance of Biopower at the Chanute Air Force Base in Rantoul, Illinois. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Scarlata, C.; Mosey, G.

    2013-05-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Former Chanute Air Force Base site in Rantoul, Illinois, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) was contacted to provide technical assistance for this project. The purpose of this study was to assess the site for a possible biopower system installation and estimate the cost, performance, and impacts of different biopower options.

  5. Fayette County Better Buildings Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Capella, Arthur [County of Fayette, Uniontown, PA (United States)

    2015-03-04

    The Fayette County Better Buildings Initiative represented a comprehensive and collaborative approach to promoting and implementing energy efficiency improvements. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. The ultimate goal of Fayette County’s Better Buildings Initiative was to implement a total of 1,067 residential energy efficiency retrofits with a minimum 15% estimated energy efficiency savings per unit. Program partners included: United States Department of Energy, Allegheny Power, and Private Industry Council of Westmoreland-Fayette, Fayette County Redevelopment Authority, and various local partners. The program was open to any Fayette County residents who own their home and meet the prequalifying conditions. The level of assistance offered depended upon household income and commitment to undergo a BPI – Certified Audit and implement energy efficiency measures, which aimed to result in at least a 15% reduction in energy usage. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. Additionally, the program had components that involved recruitment and training for employment of persons in the energy sector (green jobs), as well as marketing and implementation of a commercial or community facilities component. The residential component of Fayette County’s Better Buildings Initiative involved a comprehensive approach, providing assistance to low- moderate- and market-rate homeowners. The initiative will also coordinate activities with local utility providers to further incentivize energy efficiency improvements among qualifying homeowners. The commercial component of Fayette County’s Better Building Initiative involved grants

  6. Initiation disruptor systems and methods of initiation disruption

    Science.gov (United States)

    Baum, Dennis W

    2014-09-23

    A system that may be used as an initiation disruption system (IDS) according to one embodiment includes an explosive charge; a plurality of particles in a layer at least partially surrounding the explosive charge; and a fire suppressant adjacent the plurality of particles. A method for disabling an object according to one embodiment includes placing the system as recited above near an object; and causing the explosive charge to initiate, thereby applying mechanical loading to the object such that the object becomes disabled. Additional systems and methods are also presented. A device according to another embodiment includes a plurality of particles bound by a binder thereby defining a sidewall having an interior for receiving an explosive; and a fire suppressant adjacent the plurality of particles and binder. Additional systems and methods are also presented.

  7. Soltherm Europe Initiative: Joining forces to expand solar markets, fast

    International Nuclear Information System (INIS)

    Leun, K. van der

    2001-01-01

    The article describes the partnership formed by the European Commission and the Europe-wide Soltherm Europe Initiative. The Initiative was formed in response to the Commission's aims to extend the use of solar energy. Ten countries and two international bodies make-up membership of the Initiative. For the Commission's target of 100 million square metres of solar collectors to be installed by 2010, a rapid growth in the market will need to occur. The potential savings in energy and carbon dioxide (through solar water heaters) are discussed, and figures given. The market development options for achieving the short-term goal of 15 million square metres of collector surface by 2004, and the longer-term aim of 100 million square metres by 2010 are discussed. The Initiative aims to be a platform for integration and promoting co-operation between all parties with an interest in achieving the Commission's solar objectives. Interested parties are invited to join the Initiative

  8. Investigation of fast initialization of spacecraft bubble memory systems

    Science.gov (United States)

    Looney, K. T.; Nichols, C. D.; Hayes, P. J.

    1984-01-01

    Bubble domain technology offers significant improvement in reliability and functionality for spacecraft onboard memory applications. In considering potential memory systems organizations, minimization of power in high capacity bubble memory systems necessitates the activation of only the desired portions of the memory. In power strobing arbitrary memory segments, a capability of fast turn on is required. Bubble device architectures, which provide redundant loop coding in the bubble devices, limit the initialization speed. Alternate initialization techniques are investigated to overcome this design limitation. An initialization technique using a small amount of external storage is demonstrated.

  9. Precursor processes of human self-initiated action.

    Science.gov (United States)

    Khalighinejad, Nima; Schurger, Aaron; Desantis, Andrea; Zmigrod, Leor; Haggard, Patrick

    2018-01-15

    A gradual buildup of electrical potential over motor areas precedes self-initiated movements. Recently, such "readiness potentials" (RPs) were attributed to stochastic fluctuations in neural activity. We developed a new experimental paradigm that operationalized self-initiated actions as endogenous 'skip' responses while waiting for target stimuli in a perceptual decision task. We compared these to a block of trials where participants could not choose when to skip, but were instead instructed to skip. Frequency and timing of motor action were therefore balanced across blocks, so that conditions differed only in how the timing of skip decisions was generated. We reasoned that across-trial variability of EEG could carry as much information about the source of skip decisions as the mean RP. EEG variability decreased more markedly prior to self-initiated compared to externally-triggered skip actions. This convergence suggests a consistent preparatory process prior to self-initiated action. A leaky stochastic accumulator model could reproduce this convergence given the additional assumption of a systematic decrease in input noise prior to self-initiated actions. Our results may provide a novel neurophysiological perspective on the topical debate regarding whether self-initiated actions arise from a deterministic neurocognitive process, or from neural stochasticity. We suggest that the key precursor of self-initiated action may manifest as a reduction in neural noise. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  10. Serotonin spillover onto the axon initial segment of motoneurons induces central fatigue by inhibiting action potential initiation

    DEFF Research Database (Denmark)

    Cotel, Florence; Exley, Richard; Cragg, Stephanie

    2013-01-01

    Motor fatigue induced by physical activity is an everyday experience characterized by a decreased capacity to generate motor force. Factors in both muscles and the central nervous system are involved. The central component of fatigue modulates the ability of motoneurons to activate muscle...... adequately independently of the muscle physiology. Indirect evidence indicates that central fatigue is caused by serotonin (5-HT), but the cellular mechanisms are unknown. In a slice preparation from the spinal cord of the adult turtle, we found that prolonged stimulation of the raphe-spinal pathway......-HT during motor activity spills over from its release sites to the AIS of motoneurons. Here, activated 5-HT1A receptors inhibit firing and, thereby, muscle contraction. Hence, this is a cellular mechanism for central fatigue...

  11. Initial Semantics for Strengthened Signatures

    Directory of Open Access Journals (Sweden)

    André Hirschowitz

    2012-02-01

    Full Text Available We give a new general definition of arity, yielding the companion notions of signature and associated syntax. This setting is modular in the sense requested by Ghani and Uustalu: merging two extensions of syntax corresponds to building an amalgamated sum. These signatures are too general in the sense that we are not able to prove the existence of an associated syntax in this general context. So we have to select arities and signatures for which there exists the desired initial monad. For this, we follow a track opened by Matthes and Uustalu: we introduce a notion of strengthened arity and prove that the corresponding signatures have initial semantics (i.e. associated syntax. Our strengthened arities admit colimits, which allows the treatment of the λ-calculus with explicit substitution.

  12. Blasting agents and initiation systems

    Energy Technology Data Exchange (ETDEWEB)

    Fiscor, S.

    2000-01-01

    Although blasting differs between and within each industry, as a whole, the mines and quarries are making a shift from a purely ammonium nitrate/fuel oil (ANFO) mixture to a blend of emulsion and ANFO on a straight emulsion. Non-electric (shock tube) initiation systems have provided a viable alternative to the electric detonator (blasting cap). Explosives manufacturers are seeing their roles changes to being blasting contractors or consultants rather than just suppliers. The article discusses these trends and gives examples of typical blasting techniques and amounts of blasting agent used at large USA surface coal mines. Electric caps are still used in blasting underground coal. The Ensign Bickford Co. (EBCo) is developing electronic detonators and has been field testing an electronic initiator, the DIGIDET detonator, for the last four years. When commercially available, electronic detonators will be accurate but will come with a hefty price tag. 2 photos.

  13. Global nuclear cleanout initiative 2004

    International Nuclear Information System (INIS)

    Edlow, J.; Gruber, G.

    2004-01-01

    Full text: During more than 50 years of Atoms for Peace programmes nuclear materials were spread out worldwide. Stranded nuclear materials from nuclear research are left over without any safe back-end solution. 'Dirty Bombs' or so-called 'Radioactive Dispersal Devices (RDD)' are no longer science fiction since the world experienced the 9/11 attack. Governmental, NGO's and private industry organizations having discussed Global Nuclear Cleanout since then and start to take actions. The US Department of Energy (DOE) has announced to establish a dedicated organization in cooperation with IAEA and start the 'Global Threat Reduction Initiative (GTRI)'. The US government will allocate to that program USD 450 M over the next 10 years. Besides the historical development the paper will focus on the progress of the different initiatives and perspectives to threat reduction. (author)

  14. Initial conditions for cosmological perturbations

    Science.gov (United States)

    Ashtekar, Abhay; Gupt, Brajesh

    2017-02-01

    Penrose proposed that the big bang singularity should be constrained by requiring that the Weyl curvature vanishes there. The idea behind this past hypothesis is attractive because it constrains the initial conditions for the universe in geometric terms and is not confined to a specific early universe paradigm. However, the precise statement of Penrose’s hypothesis is tied to classical space-times and furthermore restricts only the gravitational degrees of freedom. These are encapsulated only in the tensor modes of the commonly used cosmological perturbation theory. Drawing inspiration from the underlying idea, we propose a quantum generalization of Penrose’s hypothesis using the Planck regime in place of the big bang, and simultaneously incorporating tensor as well as scalar modes. Initial conditions selected by this generalization constrain the universe to be as homogeneous and isotropic in the Planck regime as permitted by the Heisenberg uncertainty relations.

  15. Initial conditions for cosmological perturbations

    International Nuclear Information System (INIS)

    Ashtekar, Abhay; Gupt, Brajesh

    2017-01-01

    Penrose proposed that the big bang singularity should be constrained by requiring that the Weyl curvature vanishes there. The idea behind this past hypothesis is attractive because it constrains the initial conditions for the universe in geometric terms and is not confined to a specific early universe paradigm. However, the precise statement of Penrose’s hypothesis is tied to classical space-times and furthermore restricts only the gravitational degrees of freedom. These are encapsulated only in the tensor modes of the commonly used cosmological perturbation theory. Drawing inspiration from the underlying idea, we propose a quantum generalization of Penrose’s hypothesis using the Planck regime in place of the big bang, and simultaneously incorporating tensor as well as scalar modes. Initial conditions selected by this generalization constrain the universe to be as homogeneous and isotropic in the Planck regime as permitted by the Heisenberg uncertainty relations . (paper)

  16. Initial occupational exposure to lead

    Energy Technology Data Exchange (ETDEWEB)

    Forni, A.; Cambiaghi, G.; Secchi, G.C.

    1976-01-01

    Serial chromosome and biochemical studies were carried out in 11 subjects before and during initial occupational exposure to moderate quantities of lead fumes in a storage battery plant. The rate of abnormal metaphases, mostly with chromatid and one-break chromosome aberrations, was approximately doubled after one month of work; it further increased after two months of work; remained in this range up to seven months of exposure; and then tended to decrease somewhat. Blood lead levels increased progressively in the first few months, then reached a steady state. Urinary lead and coproporphyrin levels increased sharply after one month of work, while urinary delta-aminolevulinic acid (ALA) levels increased moderately. The ALA dehydratase (ALAD) activity of red blood cells (RBCs) was reduced to almost 50 percent of the initial values after one month, decreased further in subsequent months, and remained decreased through the remainder of the study.

  17. Intelligent Vehicle Initiative : business plan

    Science.gov (United States)

    1997-11-01

    Ongoing and recently completed research and development indicate that collision avoidance systems offer the potential for significantly reducing motor vehicle crashes. Preliminary estimates by the National Highway Traffic Safety Administration (NHTSA...

  18. Air sea ratio reduction initiative

    Energy Technology Data Exchange (ETDEWEB)

    Oberle, Jean

    2010-09-15

    Airfreight is the most expensive mode of transportation as well as the most impacting in terms of CO{sup 2} emissions. It is 7 times more expensive on average to ship by air than shipping by sea 1. Airfreight transportation mode emits 30 times more CO{sup 2} than sea freight mode 2. These elements provided a compelling platform to design a global logistics program to initiate a modal shift from air to sea freight without compromising service to customers.

  19. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Brisbane Baylands Brownfield Site in Brisbane, California. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Salasovich, J.; Geiger, J.; Healey, V.; Mosey, G.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Brisbane Baylands site in Brisbane, California, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  20. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Ft. Hood Military Base Outside Killeen, Texas. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Geiger, J.; Lisell, L.; Mosey, G.

    2013-10-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative through the Region 6 contract, selected Ft. Hood Army Base in Killeen, Texas, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this study is to assess the site for possible photovoltaic (PV) system installations and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  1. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Price Landfill Site in Pleasantville, New Jersey. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Salasovich, J.; Geiger, J.; Mosey, G.; Healey, V.

    2013-05-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Price Landfill site in Pleasantville, New Jersey, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site. This study did not assess environmental conditions at the site.

  2. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Kolthoff Landfill in Cleveland, Ohio. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Salasovich, J.; Geiger, J.; Mosey, G.; Healey, V.

    2013-06-01

    The U.S. Environmental Protection Agency (EPA), Region 5, in accordance with the RE-Powering America's Land initiative, selected the Kolthoff Landfill site in Cleveland, Ohio, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  3. Feasibility Study of Economics and Performance of Geothermal Power Generation at the Lakeview Uranium Mill Site in Lakeview, Oregon. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Hillesheim, M.; Mosey, G.

    2013-11-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Lakeview Uranium Mill site in Lakeview, Oregon, for a feasibility study of renewable energy production. The EPA contracted with the National Renewable Energy Laboratory (NREL) to provide technical assistance for the project. The purpose of this report is to describe an assessment of the site for possible development of a geothermal power generation facility and to estimate the cost, performance, and site impacts for the facility. In addition, the report recommends development pathways that could assist in the implementation of a geothermal power system at the site.

  4. Feasibility Study of Economics and Performance of Solar Photovoltaics at the TechCity East Campus Resource Conservation and Recovery Act Site in Kingston, New York. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Salasovich, James [National Renewable Energy Lab. (NREL), Golden, CO (United States); Geiger, Jesse W. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mosey, Gail [National Renewable Energy Lab. (NREL), Golden, CO (United States); Healey, Victoria [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2014-01-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the TechCity East Campus site in Kingston, New York, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this study is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  5. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Former Fort Ord Army Base Site in Marina, California. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Stoltenberg, B.; Konz, C.; Mosey, G.

    2013-05-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Former Fort Ord Army Base (FOAB) site in Marina, California, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  6. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Standard Chlorine of Delaware Superfund Site in Delaware City, Delaware. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Salasovich, J.; Geiger, J.; Mosey, G.; Healey, V.

    2013-06-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Standard Chlorine of Delaware site in Delaware City, Delaware, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  7. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Crazy Horse Landfill Site in Salinas, California. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Stoltenberg, B.; Konz, C.; Mosey, G.

    2013-03-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Crazy Horse Landfill site in Salinas, California, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) was contacted to provide technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, operation and maintenance requirements, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  8. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Sky Park Landfill Site in Eau Claire, Wisconsin. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Simon, J.; Mosey, G.

    2013-01-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Sky Park Landfill site in Eau Claire, Wisconsin, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  9. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Kerr McGee Site in Columbus, Mississippi. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Simon, J.; Mosey, G.

    2013-01-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Kerr McGee site in Columbus, Mississippi, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  10. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Tronox Facility in Savannah, Georgia. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Kiatreungwattana, K.; Geiger, J.; Healey, V.; Mosey, G.

    2013-03-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Tronox Facility site in Savannah, Georgia, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  11. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Chino Mine in Silver City, New Mexico. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Kiatreungwattana, K.; Geiger, J.; Healey, V.; Mosey, G.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Chino Mine site in Silver City, New Mexico, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  12. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Former Bethlehem Steel Plant Brownfield Site in Lackawanna, New York. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Salasovich, J.; Geiger, J.; Mosey, G.; Healey, V.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Former Bethlehem Steel Plant site in Lackawanna, New York, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  13. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Peru Mill Industrial Park in the City of Deming, New Mexico. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Kiatreungwattana, K.; Geiger, J.; Healey, V.; Mosey, G.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Peru Mill Industrial Park site in the City of Deming, New Mexico, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  14. Feasibility Study of Anaerobic Digestion of Food Waste in St. Bernard, Louisiana. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, K.

    2013-01-01

    The U.S. Environmental Protection Agency (EPA) developed the RE-Powering America's Land initiative to re-use contaminated sites for renewable energy generation when aligned with the community's vision for the site. The former Kaiser Aluminum Landfill in St. Bernard Parish, Louisiana, was selected for a feasibility study under the program. Preliminary work focused on selecting a biomass feedstock. Discussions with area experts, universities, and the project team identified food wastes as the feedstock and anaerobic digestion (AD) as the technology.

  15. Feasibility Study of Economics and Performance of Biomass Power Generation at the Former Farmland Industries Site in Lawrence, Kansas. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Tomberlin, G.; Mosey, G.

    2013-03-01

    Under the RE-Powering America's Land initiative, the U.S. Environmental Protection Agency (EPA) provided funding to the National Renewable Energy Laboratory (NREL) to support a feasibility study of biomass renewable energy generation at the former Farmland Industries site in Lawrence, Kansas. Feasibility assessment team members conducted a site assessment to gather information integral to this feasibility study. Information such as biomass resources, transmission availability, on-site uses for heat and power, community acceptance, and ground conditions were considered.

  16. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Tower Road Site in Aurora, Colorado. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Van Geet, O.; Mosey, G.

    2013-03-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Tower Road site in Aurora, Colorado, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site. This study did not assess environmental conditions at the site.

  17. Cosmology with exponential potentials

    International Nuclear Information System (INIS)

    Kehagias, Alex; Kofinas, Georgios

    2004-01-01

    We examine in the context of general relativity the dynamics of a spatially flat Robertson-Walker universe filled with a classical minimally coupled scalar field φ of exponential potential V(φ) ∼ exp(-μφ) plus pressureless baryonic matter. This system is reduced to a first-order ordinary differential equation for Ω φ (w φ ) or q(w φ ), providing direct evidence on the acceleration/deceleration properties of the system. As a consequence, for positive potentials, passage into acceleration not at late times is generically a feature of the system for any value of μ, even when the late-times attractors are decelerating. Furthermore, the structure formation bound, together with the constraints Ω m0 ∼ 0.25 - 0.3, -1 ≤ w φ0 ≤ -0.6, provides, independently of initial conditions and other parameters, the necessary condition 0 N , while the less conservative constraint -1 ≤ w φ ≤ -0.93 gives 0 N . Special solutions are found to possess intervals of acceleration. For the almost cosmological constant case w φ ∼ -1, the general relation Ω φ (w φ ) is obtained. The generic (nonlinearized) late-times solution of the system in the plane (w φ , Ω φ ) or (w φ , q) is also derived

  18. Industry's Commercial Initiatives on ISS

    Science.gov (United States)

    Shields, C. E.; Kessler, C.; Lavitola, M. S.

    2002-01-01

    For more than ten years, private industry has worked to develop a commercial human space market and to create a sustainable ISS commercial utilization customer base. Before ISS assembly was underway - and long before NASA and the international space agencies began to craft ISS commercial business terms and conditions - industry planted and nurtured the seeds of interest in exploiting human space utilization for commerce. These early initiatives have yielded the impetus and framework for industry approaches to ISS commercial utilization today and for NASA's and the International Partners' planned accommodation of private sector interests and desires on the ISS. This paper chronicles major industry initiatives for commercial ISS utilization, emphasizing successful marketing and business approaches and why these approaches have a higher likelihood of success than others. It provides an overview of individual companies' initiatives, as well as collaborative efforts that cross company lines and country borders; and it assesses the relative success of each. Rather than emphasize negative issues and barriers, this paper characterizes and prioritizes actionable success factors for industry and government to make ISS commercial utilization a sustainable reality.

  19. Revised CTUIR Renewable Energy Feasibility Study Final Report

    Energy Technology Data Exchange (ETDEWEB)

    John Cox; Thomas Bailor; Theodore Repasky; Lisa Breckenridge

    2005-10-31

    This preliminary assessment of renewable energy resources on the Umatilla Indian Reservation (UIR) has been performed by CTUIR Department of Science and Engineering (DOSE). This analysis focused primarily identifying renewable resources that may be applied on or near the Umatilla Indian Reservation. In addition preliminary technical and economic feasibility of developing renewable energy resources have been prepared and initial land use planning issues identified. Renewable energies examined in the course of the investigation included solar thermal, solar photovoltaic, wind, bioethanol, bio-diesel and bio-pellet fuel. All renewable energy options studied were found to have some potential for the CTUIR. These renewable energy options are environmentally friendly, sustainable, and compliment many of the policy goals of the CTUIR. This report seeks to provide an overall review of renewable energy technologies and applications. It tries to identify existing projects near to the CTUIR and the efforts of the federal government, state government and the private sector in the renewable energy arena. It seeks to provide an understanding of the CTUIR as an energy entity. This report intends to provide general information to assist tribal leadership in making decisions related to energy, specifically renewable energy deve lopment.

  20. The next generation safeguards initiative

    International Nuclear Information System (INIS)

    Tobey, William

    2008-01-01

    NGSI or the Next Generation Safeguards Initiative is designed to revitalize the U.S. safeguards technical base, as well as invest in human resources, and to mobilize our primary asset - the U.S. National Laboratories - as well as industry and academia to restore capabilities. While NGSI is a U.S. effort it is intended to serve as a catalyst for a much broader commitment to international safeguards in partnership with the IAEA and other countries. Initiatives over the last years include such as the Proliferation Security Initiative, UN Security Council Resolution 1540, the Global Initiative to Combat Nuclear Terrorism, and initiatives of the G-8 and NSG to discourage the spread of enrichment and reprocessing. NGSI augments this agenda by providing a means to strengthen the technical and political underpinnings of IAEA safeguards. Priorities and envisioned activities under NGSI are the following. (1) Cooperation with IAEA and others to promote universal adoption of safeguards agreements and the Additional Protocol including greater information sharing between member states and the IAEA, investigation of weaponization and procurement activities, and options to strengthen the state-level approach to safeguards. (2) NGSI anticipates the deployment of new types of reactors and fuel cycle facilities, as well as the need to use limited safeguards resources effectively and efficiently, especially in plants that pose the largest burden specifically complex, bulk-handling facilities. (3) NGSI will encourage a generational improvement in current safeguards technologies including improvement of precision and speed of nuclear measurements, performance of real-time process monitoring and surveillance in unattended mode, enabling in-field, pre-screening and analysis of nuclear and environmental samples, and collection, integration, analysis and archiving safeguards-relevant information from all available sources.(4) NGSI will address human capital management. Training and

  1. OPM: The Open Porous Media Initiative

    Science.gov (United States)

    Flemisch, B.; Flornes, K. M.; Lie, K.; Rasmussen, A.

    2011-12-01

    The principal objective of the Open Porous Media (OPM) initiative is to develop a simulation suite that is capable of modeling industrially and scientifically relevant flow and transport processes in porous media and bridge the gap between the different application areas of porous media modeling, including reservoir mechanics, CO2 sequestration, biological systems, and product development of engineered media. The OPM initiative will provide a long-lasting, efficient, and well-maintained open-source software for flow and transport in porous media built on modern software principles. The suite is released under the GNU General Public License (GPL). Our motivation is to provide a means to unite industry and public research on simulation of flow and transport in porous media. For academic users, we seek to provide a software infrastructure that facilitates testing of new ideas on models with industry-standard complexity, while at the same time giving the researcher control over discretization and solvers. Similarly, we aim to accelerate the technology transfer from academic institutions to professional companies by making new research results available as free software of professional standard. The OPM initiative is currently supported by six research groups in Norway and Germany and funded by existing grants from public research agencies as well as from Statoil Petroleum and Total E&P Norge. However, a full-scale development of the OPM initiative requires substantially more funding and involvement of more research groups and potential end users. In this talk, we will provide an overview of the current activities in the OPM initiative. Special emphasis will be given to the demonstration of the synergies achieved by combining the strengths of individual open-source software components. In particular, a new fully implicit solver developed within the DUNE-based simulator DuMux could be enhanced by the ability to read industry-standard Eclipse input files and to run on

  2. Chemical structures and thermal properties of polyesters obtained from different samples of bio diesel epoxidized; Estruturas quimicas e propriedades termicas de poliesteres obtidos a partir de diferentes tipos de biodiesel epoxidado

    Energy Technology Data Exchange (ETDEWEB)

    Samios, Dimitrios; Reiznautt, Quelen B.; Nicolau, Aline; Martini, Denise D.; Chagas, Arthur L. das, E-mail: dsamios@iq.ufrgs.b [Universidade Federal do Rio Grande do Sul (IQ/UFRGS), Porto Alegre, RS (Brazil). Inst. de Quimica. Lab. de Instrumentacao e Dinamica Molecular

    2009-07-01

    In this work new structures from oligo esters and polyesters from different oils (olive oil, sunflower oil and linseed oil) were synthesized and characterized. Oligo esters and polyesters were synthesized from the reaction of fatty acid methyl epoxy-esters, obtained from different oils, with cis-1,2-cyclohexanedicarboxylic anhydride in the presence of triethylamine (TEA). Different amounts of the resin 1,4-butanediol diglycidyl ether (BDGE) were added in order to increase the capacity of crosslinking. The molar ratio of BDGE used in system was between 0 and 0.066. The intermediate structures, as well as the oligo esters and polyesters produced, were analyzed by using Fourier Transform Infrared Spectroscopy and Nuclear Magnetic Resonance ({sup 1}H - NMR). The thermal behavior of the products was realized through differential scanning calorimetry and Thermogravimetric analyses. The presence of BDGE in the materials chains increases the bonding capacity resulting in a higher molecular weight material which presents good thermal stability. (author)

  3. Women's Health Initiative (WHI) Background and Overview

    Science.gov (United States)

    ... Back To The Science / Women’s Health Initiative (WHI) Women’s Health Initiative (WHI) Project began 1991 Point of ... What is the goal of the WHI? The Women's Health Initiative (WHI), sponsored by the National Heart, ...

  4. 75 FR 11837 - Chesapeake Bay Watershed Initiative

    Science.gov (United States)

    2010-03-12

    ... DEPARTMENT OF AGRICULTURE Commodity Credit Corporation Chesapeake Bay Watershed Initiative AGENCY...: Notice of availability of program funds for the Chesapeake Bay Watershed Initiative. SUMMARY: The... through the Chesapeake Bay Watershed Initiative for agricultural producers in the Chesapeake Bay watershed...

  5. ADVERGAMES: CHARACTERISTICS, LIMITATIONS AND POTENTIAL

    Directory of Open Access Journals (Sweden)

    Gurau Calin

    2010-07-01

    Full Text Available Advergames represent a new advertising concept that uses Internet technology to implement viral marketing campaigns. Despite the potential of this interactive advertising method, very few academic studies have been initiated to investigate the characteristics of advergames, and their influence on consumers’ perceptions and behaviour. Using secondary data, this paper attempts to evaluate the characteristics of effective advergames, and to analyse the effect of advergames on players’ perceptions and behaviour.

  6. Potential Psychiatric Uses for MDMA

    OpenAIRE

    Yazar?Klosinski, BB; Mithoefer, MC

    2017-01-01

    Phase II trials of 3,4?methylenedioxymethamphetamine (MDMA)?assisted psychotherapy have demonstrated initial safety and efficacy for treatment of posttraumatic stress disorder (PTSD), with potential for expansion to depression and anxiety disorders. In these trials, single doses of MDMA are administered in a model of medication?assisted psychotherapy, differing from trials involving daily drug administration without psychotherapy. This model presents an opportunity to utilize accelerated regu...

  7. Geothermal Direct Heat Application Potential

    Energy Technology Data Exchange (ETDEWEB)

    Lienau, Paul J

    1989-01-01

    The geothermal direct-use industry growth trends, potential, needs, and how they can be met, are addressed. Recent investigations about the current status of the industry and the identification of institutional and technical needs provide the basis on which this paper is presented. Initial drilling risk is the major obstacle to direct-use development. The applications presented include space and district heating projects, heat pumps (heating and cooling), industrial processes, resorts and pools, aquaculture and agriculture.

  8. Molecular potentials and relaxation dynamics

    International Nuclear Information System (INIS)

    Karo, A.M.

    1981-01-01

    The use of empirical pseudopotentials, in evaluating interatomic potentials, provides an inexpensive and convenient method for obtaining highly accurate potential curves and permits the modeling of core-valence correlation, and the inclusion of relativistic effects when these are significant. Recent calculations of the X 1 Σ + and a 3 Σ + states of LiH, NaH, KH, RbH, and CsH and the X 2 Σ + states of their anions are discussed. Pseudopotentials, including core polarization terms, have been used to replace the core electrons, and this has been coupled with the development of compact, higly-optimized basis sets for the corresponding one- and two-electron atoms. Comparisons of the neutral potential curves with experiment and other ab initio calculations show good agreement (within 1000 cm -1 over most of the potential curves) with the difference curves being considerably more accurate. In the method of computer molecular dynamics, the force acting on each particle is the resultant of all interactions with other atoms in the neighborhood and is obtained as the derivative of an effective many-body potential. Exploiting the pseudopotential approach, in obtaining the appropriate potentials may be very fruitful in the future. In the molecular dynamics example considered here, the conventional sum-of-pairwise-interatomic-potentials (SPP) approximation is used with the potentials derived either from experimental spectroscopic data or from Hartree-Fock calculations. The problem is the collisional de-excitation of vibrationally excited molecular hydrogen at an Fe surface. The calculations have been carried out for an initial vibrotational state v = 8, J = 1 and a translational temperature corresponding to a gas temperature of 500 0 K. Different angles of approach and different initial random impact points on the surface have been selected. For any given collision with the wall, the molecule may pick up or lose vibrotatonal and translational energy

  9. University engagement and regional sustainability initiatives

    DEFF Research Database (Denmark)

    Lehmann, Martin; Christensen, Per; Thrane, Mikkel

    2009-01-01

    With an outset in ‘sustainability' defined as a continuous process requiring balance between (the emergence of) problems and our ability and capability to solve them using four distinct capitals available, i.e. natural, production, human and intellectual, and social capital, a model of universities...... University, Denmark, the linkages (actual, potential and missing) between academic work in research and education and sustainability initiatives are explored. The focus is both on the university's core activities as a provider of research and education and on the university's activities as an organisation, i...... societal benefit would be the ability to better cope with emerging problems endangering the sustainable development of our societies. It is concluded that Aalborg University with its long tradition for project-based and problem-oriented learning in fact has every opportunity to be able to lead by example...

  10. An analytic initial-state parton shower

    Energy Technology Data Exchange (ETDEWEB)

    Kilian, W. [Siegen Univ. (Germany). Dept. Physik; Reuter, J.; Schmidt, S.; Wiesler, D. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2011-12-15

    We present a new algorithm for an analytic parton shower. While the algorithm for the final-state shower has been known in the literature, the construction of an initial-state shower along these lines is new. The aim is to have a parton shower algorithm for which the full analytic form of the probability distribution for all branchings is known. For these parton shower algorithms it is therefore possible to calculate the probability for a given event to be generated, providing the potential to reweight the event after the simulation. We develop the algorithm for this shower including scale choices and angular ordering. Merging to matrix elements is used to describe high-energy tails of distributions correctly. Finally, we compare our results with those of other parton showers and with experimental data from LEP, Tevatron and LHC. (orig.)

  11. Homestake surface-underground scintillators: Initial results

    International Nuclear Information System (INIS)

    Cherry, M.L.; Corbato, S.; Daily, T.; Fenyves, E.J.; Kieda, D.; Lande, K.; Lee, C.K.

    1986-01-01

    The first 70 tons of the 140-ton Large Area Scintillation Detector (LASD) have been operating since Jan. 1985 at a depth of 4850 ft. (4200 m.w.e.) in the Homestake Gold Mine, Lead, S.D. A total of 4 x 10(4) high-energy muons (E sub mu is approx. 2.7 TeV at the surface) have been detected. The remainder of the detector is scheduled to be in operation by the Fall of 1985. In addition, a surface air shower array is under construction. The first 27 surface counters, spaced out over an area of 270' x 500', began running in June, 1985. The LASD performance, the potential of the combined shower array and underground muon experiment for detecting point sources, and the initial results of a search for periodic emission from Cygnus X-3 are discussed

  12. An analytic initial-state parton shower

    International Nuclear Information System (INIS)

    Kilian, W.

    2011-12-01

    We present a new algorithm for an analytic parton shower. While the algorithm for the final-state shower has been known in the literature, the construction of an initial-state shower along these lines is new. The aim is to have a parton shower algorithm for which the full analytic form of the probability distribution for all branchings is known. For these parton shower algorithms it is therefore possible to calculate the probability for a given event to be generated, providing the potential to reweight the event after the simulation. We develop the algorithm for this shower including scale choices and angular ordering. Merging to matrix elements is used to describe high-energy tails of distributions correctly. Finally, we compare our results with those of other parton showers and with experimental data from LEP, Tevatron and LHC. (orig.)

  13. Industry and the environment - voluntary initiatives

    International Nuclear Information System (INIS)

    Olsen, K.; Guldborg, S.

    1997-01-01

    For some time industry in general has sought to take visible initiatives which demonstrate its sense of responsibility in respect of the environment. A main motivation is to ensure a business based approach, to establish a partnership with policy makers, which will reduce the necessity of command and control measures. In 1989 the European Commission invited Eurogas and other energy industries to develop Codes of Conduct in relation to the environment, based on specific guiding principles. The natural gas industry continues to seek ways to build on the advantages of its product and to aim for all-round improvement with regard to environmental policies. The potential and importance of the Environmental Management Systems (EMSs) is increasingly developed by companies within Europe and internationally. The key elements of the proposed EMS system for the gas industry are presented in detail. (R.P.)

  14. HST Replacement Battery Initial Performance

    Science.gov (United States)

    Krol, Stan; Waldo, Greg; Hollandsworth, Roger

    2009-01-01

    The Hubble Space Telescope (HST) original Nickel-Hydrogen (NiH2) batteries were replaced during the Servicing Mission 4 (SM4) after 19 years and one month on orbit.The purpose of this presentation is to highlight the findings from the assessment of the initial sm4 replacement battery performance. The batteries are described, the 0 C capacity is reviewed, descriptions, charts and tables reviewing the State Of Charge (SOC) Performance, the Battery Voltage Performance, the battery impedance, the minimum voltage performance, the thermal performance, the battery current, and the battery system recharge ratio,

  15. Initial CAD investigations for NET

    International Nuclear Information System (INIS)

    Katz, F.; Leinemann, K.; Ludwig, A.; Marek, U.; Olbrich, W.; Schlechtendahl, E.G.

    1985-11-01

    This report summarizes the work done under contract no. 164/84-7/FU-D-/NET between the Commission of the European Communities and KfK during the period from June 1, 1984, through May 31, 1985. The following topics are covered in this report: Initial modelling of NET version NET2A, CAD system extension for remote handling studies, analysis of the CAD information structure, work related to the transfer of CAD information between KfK and the NET team. (orig.) [de

  16. Powering the Space Exploration Initiative

    International Nuclear Information System (INIS)

    Bennett, G.L.

    1991-01-01

    The Space Exploration Initiative (SEI) establishes the long-term goal of returning to the Moon and then exploring Mars. One of the prerequisites of SEI is the Exploration Technology Program which includes program elements on space nuclear power and surface solar power. These program elements in turn build upon the ongoing NASA research and technology base program in space energy conversion. There is a wide range of missions in NASA's strategic planning and most would benefit from power sources with improved efficiency, lighter weight and reduced cost

  17. Initial treatment of Parkinson's disease.

    Science.gov (United States)

    Tarsy, Daniel

    2006-05-01

    Initial treatment of early idiopathic Parkinson's disease (PD) begins with diagnosis based on clinical evaluation supplemented by laboratory studies and brain imaging to exclude causes of secondary parkinsonism. In most cases, testing is normal and the diagnosis of PD rests on clinical criteria. In patients with mild symptoms and signs, the diagnosis of PD may not initially be apparent, and follow-up evaluation is needed to arrive at a diagnosis. Once the diagnosis is made, pharmacologic treatment may not be the first step. First, patient education is essential, especially because PD is a high-profile disease for which information and misinformation are readily available to patients and families. Counseling concerning prognosis, future symptoms, future disability, and treatment must be provided. Questions from patients concerning diet, lifestyle, and exercise are especially common at this point. The decision of when to initiate treatment is the next major consideration. Much controversy but relatively little light has been brought to bear on this issue. L-dopa was the first major antiparkinson medication to be introduced and remains the "gold standard" of treatment. Next in efficacy are the dopamine agonists (DAs). A debate has raged concerning whether initial dopaminergic treatment should be with L-dopa or DAs. Physicians have been concerned about forestalling the appearance of dyskinesias and motor fluctuations, whereas patients have incorrectly understood that L-dopa and possibly other antiparkinson drugs have a finite duration of usefulness, making it important to defer treatment for as long as possible. This has created "L-dopa phobia," which may stand in the way of useful treatment. In spite of this controversy, there is uniform agreement that the appropriate time to treat is when the patient is beginning to be disabled. This varies from patient to patient and depends on age, employment status, nature of job, level of physical activity, concern about

  18. Interstellar Initiative Web Page Design

    Science.gov (United States)

    Mehta, Alkesh

    1999-01-01

    This summer at NASA/MSFC, I have contributed to two projects: Interstellar Initiative Web Page Design and Lenz's Law Relative Motion Demonstration. In the Web Design Project, I worked on an Outline. The Web Design Outline was developed to provide a foundation for a Hierarchy Tree Structure. The Outline would help design a Website information base for future and near-term missions. The Website would give in-depth information on Propulsion Systems and Interstellar Travel. The Lenz's Law Relative Motion Demonstrator is discussed in this volume by Russell Lee.

  19. [Initial stages of steel biocorrosion].

    Science.gov (United States)

    Zhigletsova, S K; Rodin, V B; Kobelev, V S; Aleksandrova, N V; Rasulova, G E; Kholodenko, V P

    2000-01-01

    Initial stages of corrosion of mild steel induced by Klebsiela rhinoscleromatis BO2 were studied in various media. The effect of the microorganism was detected 8-10 h after inoculation. The number of viable cells were virtually unchanged within one month in all media, but the corrosive activity of the strain decreased. The corrosive activity of microorganisms can be determined by spectrophotometry even only after incubation for 24 h. At a low level of organic substrate, even strong colonization with microorganisms does not inevitably result in a significant damage to metals.

  20. Radiation safety without borders initiative

    International Nuclear Information System (INIS)

    Dibblee, Martha; Dickson, Howard; Krieger, Ken; Lopez, Jose; Waite, David; Weaver, Ken

    2008-01-01

    The Radiation Safety Without Borders (RSWB) initiative provides peer support to radiation safety professionals in developing countries, which bolsters the country's infrastructure and may lead the way for IRPA Associate membership. The Health Physics Society (HPS) recognizes that many nations do not possess the infrastructure to adequately control and beneficially use ionizing radiation. In a substantial number of countries, organized radiation protection programs are minimal. The RSWB initiative relies on HPS volunteers to assist their counterparts in developing countries with emerging health physics and radiation safety programs, but whose resources are limited, to provide tools that promote and support infrastructure and help these professionals help themselves. RSWB experience to date has shown that by providing refurbished instruments, promoting visits to a HPS venue, or visiting a country just to look provide valuable technical and social infrastructure experiences often missing in the developing nation's cadre of radiation safety professionals. HPS/RSWB with the assistance of the International Atomic Energy Agency (IAEA) pairs chapters with a country, with the expectation that the country's professional radiation safety personnel will form a foreign HPS chapter, and the country eventually will become an IRPA Associate. Although still in its formative stage, RSWB nonetheless has gotten valuable information in spite of the small number of missions. The RSWB initiative continues to have significant beneficial impacts, including: Improving the radiation safety infrastructure of the countries that participate; Assisting those countries without professional radiation safety societies to form one; Strengthening the humanitarian efforts of the United States; Enhancing Homeland Security efforts through improved control of radioactive material internationally. Developing countries, including those in Latin America, underwritten by IAEA, may take advantage of resources

  1. Initial perspectives on process threat management

    International Nuclear Information System (INIS)

    Whiteley, James R. Rob; Mannan, M. Sam

    2004-01-01

    Terrorist and criminal acts are now considered credible risks in the process industries. Deliberate attacks on the nation's petroleum refineries and chemical plants would pose a significant threat to public welfare, national security, and the US economy. To-date, the primary response of government and industry has been on improved security to prevent attacks and the associated consequences. While prevention is clearly preferred, the potential for successful attacks must be addressed. If plant security is breached, the extent of the inflicted damage is determined by the available plant safety systems and procedures. We refer to this 'inside the gate' response as process threat management. The authors have initiated a joint industry/academia study to address: - the level of safety provided by existing plant equipment and safety systems in response to a terrorist act, and; - identification of process (rather than security) needs or opportunities to address this new safety concern. This paper describes the initial perspectives and issues identified by the team at the beginning of the study

  2. Neuron Morphology Influences Axon Initial Segment Plasticity.

    Science.gov (United States)

    Gulledge, Allan T; Bravo, Jaime J

    2016-01-01

    In most vertebrate neurons, action potentials are initiated in the axon initial segment (AIS), a specialized region of the axon containing a high density of voltage-gated sodium and potassium channels. It has recently been proposed that neurons use plasticity of AIS length and/or location to regulate their intrinsic excitability. Here we quantify the impact of neuron morphology on AIS plasticity using computational models of simplified and realistic somatodendritic morphologies. In small neurons (e.g., dentate granule neurons), excitability was highest when the AIS was of intermediate length and located adjacent to the soma. Conversely, neurons having larger dendritic trees (e.g., pyramidal neurons) were most excitable when the AIS was longer and/or located away from the soma. For any given somatodendritic morphology, increasing dendritic membrane capacitance and/or conductance favored a longer and more distally located AIS. Overall, changes to AIS length, with corresponding changes in total sodium conductance, were far more effective in regulating neuron excitability than were changes in AIS location, while dendritic capacitance had a larger impact on AIS performance than did dendritic conductance. The somatodendritic influence on AIS performance reflects modest soma-to-AIS voltage attenuation combined with neuron size-dependent changes in AIS input resistance, effective membrane time constant, and isolation from somatodendritic capacitance. We conclude that the impact of AIS plasticity on neuron excitability will depend largely on somatodendritic morphology, and that, in some neurons, a shorter or more distally located AIS may promote, rather than limit, action potential generation.

  3. Phillips Laboratory small satellite initiatives

    Science.gov (United States)

    Lutey, Mark K.; Imler, Thomas A.; Davis, Robert J.

    1993-09-01

    The Phillips Laboratory Space Experiments Directorate in conjunction with the Air Force Space Test Program (AF STP), Defense Advanced Research and Projects Agency (DARPA) and Strategic Defense Initiative Organization (SDIO), are managing five small satellite program initiatives: Lightweight Exo-Atmospheric Projectile (LEAP) sponsored by SDIO, Miniature Sensor Technology Integration (MSTI) sponsored by SDIO, Technology for Autonomous Operational Survivability (TAOS) sponsored by Phillips Laboratory, TechSat sponsored by SDIO, and the Advanced Technology Standard Satellite Bus (ATSSB) sponsored by DARPA. Each of these spacecraft fulfills a unique set of program requirements. These program requirements range from a short-lived `one-of-a-kind' mission to the robust multi- mission role. Because of these diverging requirements, each program is driven to use a different design philosophy. But regardless of their design, there is the underlying fact that small satellites do not always equate to small missions. These spacecraft with their use of or ability to insert new technologies provide more capabilities and services for their respective payloads which allows the expansion of their mission role. These varying program efforts culminate in an ATSSB spacecraft bus approach that will support moderate size payloads, up to 500 pounds, in a large set of orbits while satisfying the `cheaper, faster, better' method of doing business. This technical paper provides an overview of each of the five spacecraft, focusing on the objectives, payoffs, technologies demonstrated, and program status.

  4. The Saudi Initiative for asthma

    Directory of Open Access Journals (Sweden)

    Al-Moamary Mohamed

    2009-01-01

    Full Text Available The Saudi Initiative for Asthma (SINA provides up-to-date guidelines for healthcare workers managing patients with asthma. SINA was developed by a panel of Saudi experts with respectable academic backgrounds and long-standing experience in the field. SINA is founded on the latest available evidence, local literature, and knowledge of the current setting in Saudi Arabia. Emphasis is placed on understanding the epidemiology, pathophysiology, medications, and clinical presentation. SINA elaborates on the development of patient-doctor partnership, self-management, and control of precipitating factors. Approaches to asthma treatment in SINA are based on disease control by the utilization of Asthma Control Test for the initiation and adjustment of asthma treatment. This guideline is established for the treatment of asthma in both children and adults, with special attention to children 5 years and younger. It is expected that the implementation of these guidelines for treating asthma will lead to better asthma control and decrease patient utilization of the health care system.

  5. Tobacco Free School Environment Initiative (Eritrea) | CRDI - Centre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Tobacco Free School Environment Initiative (Eritrea). The looming tobacco epidemic and its potential for thwarting the development process, has prompted most governments in sub-Saharan Africa to ratify the World Health Organization's Framework Convention on Tobacco Control (WHO FCTC). Ratifying countries must ...

  6. Food donation : an initiative to mitigate hunger in the world

    NARCIS (Netherlands)

    Mejia, Gonzalo; Mejia Argueta, Christopher; Rangel, Vivian; García-Díaz, César; Montoya, Carlos; Agudelo, I. (Isabel)

    2015-01-01

    Hundreds of thousands of tons of food are either lost or wasted while millions of people suffer from malnutrition. A plausible initiative are the food banks in which large retail chains and potentially other organizations can donate food. This food is collected and delivered by food banks to people

  7. Policy initiatives to promote healthy aging.

    Science.gov (United States)

    Infeld, Donna Lind; Whitelaw, Nancy

    2002-08-01

    An overwhelming array of policies and programs can be used to help older people (and future older people) maintain healthy lifestyles. How can clinicians help ensure that their patients take advantage of these opportunities? How can these broad-scope policies, educational and information initiatives, and direct service programs be turned into tools to help older people maximize health and independence? First, physicians do not need to do it all themselves. They need to know where to send their patients. For example, case managers in local aging service organizations and social workers, nurses, and discharge planners in hospitals can help connect elderly patients to appropriate benefits and services. Physicians play a critical role in creating a bridge between patients and the array of programs and information that can help them change their individual patterns of behavior. A serious lack of integration exists between what is known about healthy behaviors and lifestyles and what is really happening and available to older people today. From the earlier articles in this issue we know that much can be done to prevent many types of age-related disease and disability. This article provides examples of mechanisms that can be used to broadly disseminate knowledge about effective behavior and treatment changes and create mechanisms to turn this knowledge into real and widespread client-level, practice-level, health system, and community-wide interventions. Second, physicians need to understand that they are not merely subject to these policies and initiatives. They can help formulate and shape them. This political involvement includes active participation in policy initiatives of professional associations, involvement in research and demonstration activities, keeping informed about policy proposals at the federal and state levels, and helping advance ideas for improving health behaviors by speaking up and working toward change. These changes go beyond health initiatives to

  8. The international surface temperature initiative

    Science.gov (United States)

    Thorne, P. W.; Lawrimore, J. H.; Willett, K. M.; Allan, R.; Chandler, R. E.; Mhanda, A.; de Podesta, M.; Possolo, A.; Revadekar, J.; Rusticucci, M.; Stott, P. A.; Strouse, G. F.; Trewin, B.; Wang, X. L.; Yatagai, A.; Merchant, C.; Merlone, A.; Peterson, T. C.; Scott, E. M.

    2013-09-01

    The aim of International Surface Temperature Initiative is to create an end-to-end process for analysis of air temperature data taken over the land surface of the Earth. The foundation of any analysis is the source data. Land surface air temperature records have traditionally been stored in local, organizational, national and international holdings, some of which have been available digitally but many of which are available solely on paper or as imaged files. Further, economic and geopolitical realities have often precluded open sharing of these data. The necessary first step therefore is to collate readily available holdings and augment these over time either through gaining access to previously unavailable digital data or through data rescue and digitization activities. Next, it must be recognized that these historical measurements were made primarily in support of real-time weather applications where timeliness and coverage are key. At almost every long-term station it is virtually certain that changes in instrumentation, siting or observing practices have occurred. Because none of the historical measures were made in a metrologically traceable manner there is no unambiguous way to retrieve the true climate evolution from the heterogeneous raw data holdings. Therefore it is desirable for multiple independent groups to produce adjusted data sets (so-called homogenized data) to adequately understand the data characteristics and estimate uncertainties. Then it is necessary to benchmark the performance of the contributed algorithms (equivalent to metrological software validation) through development of realistic benchmark datasets. In support of this, a series of successive benchmarking and assessment cycles are envisaged, allowing continual improvement while avoiding over-tuning of algorithms. Finally, a portal is proposed giving access to related data-products, utilizing the assessment results to provide guidance to end-users on which product is the most suited to

  9. Quantum Phase Spase Representation for Double Well Potential

    OpenAIRE

    Babyuk, Dmytro

    2002-01-01

    A behavior of quantum states (superposition of two lowest eigenstates, Gaussian wave packet) in phase space is studied for one and two dimensional double well potential. Two dimensional potential is constructed from double well potential coupled linearly and quadratically to harmonic potential. Quantum trajectories are compared with classical ones. Preferable tunneling path in phase space is found. An influence of energy of initial Gaussian wave packet and trajectory initial condition on tunn...

  10. 36 CFR 902.60 - Initial determination.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Initial determination. 902.60... INFORMATION ACT Time Limitations § 902.60 Initial determination. (a) An initial determination whether or not... workdays in accordance with § 902.62. (b) Upon making initial determination, the Administrative Officer...

  11. 42 CFR 405.803 - Initial determination.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Initial determination. 405.803 Section 405.803....803 Initial determination. (a) Carriers make initial determinations regarding claims for benefits under Medicare Part B. (b) An initial determination for purposes of this subpart includes determinations...

  12. ACHP | Summary of the Preserve America Initiative

    Science.gov (United States)

    Initiative Preserve America: Explore and Enjoy Our Heritage (logo) Summary of the Preserve America Initiative Preserve America is a White House initiative that encourages and supports community efforts to preserve and enjoy our priceless cultural and natural heritage. The goals of the initiative include a greater shared

  13. Measuring E-cigarette dependence: Initial guidance.

    Science.gov (United States)

    Bold, Krysten W; Sussman, Steve; O'Malley, Stephanie S; Grana, Rachel; Foulds, Jonathan; Fishbein, Howard; Krishnan-Sarin, Suchitra

    2018-04-01

    E-cigarette use rates are increasing among youth and adults, despite limited knowledge about the safety, risks, and potential for this product in substituting for or reducing other tobacco use. Understanding how to characterize and assess e-cigarette dependence will be important for evaluating the public health impact of e-cigarettes and considering prevention and intervention strategies. To provide an initial review of constructs to consider when assessing e-cigarette dependence, a content expert group within the Tobacco Center for Regulatory Science (TCORS) Measurement Workgroup engaged in a review of published manuscripts and 12 tobacco dependence measures, followed by review of suggested dependence domains by a 10-person external subject-matter expert panel. The final domains selected to be considered in the development of a measure of e-cigarette dependence included: 1) Quantity and frequency of use, 2) Tolerance, 3) Perceived benefits, 4) Withdrawal symptoms, 5) Craving/urge to use, 6) Use despite harm, 7) Impaired control, 8) Automaticity, 9) Preferred over competing rewards, and 10) Sensory dependence. Similarities and differences in potential features of e-cigarette dependence compared with dependence on other tobacco products is discussed. Future work will evaluate these dependence items and constructs in a sample of e-cigarette users with a goal of developing a valid, brief, standardized measure of e-cigarette dependence. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Global threat reduction initiative (GTRI)

    International Nuclear Information System (INIS)

    Chamberlain, Travis

    2009-01-01

    The Global Threat Reduction Initiative (GTRI) is a vital part of the global efforts to combat nuclear terrorism. GTRI's unique mission to reduce and protect vulnerable nuclear and radiological material located at civilian sites both in the United States and abroad directly addresses recommendations of the bipartisan 9/11 Commission. GTRI efforts are focused on the first line of defense, namely securing or removing vulnerable nuclear and radiological material at the source. The international community has promulgated guidance on the best practice on the technical and administrative aspects of radiological source security, and the GTRI seeks to provide technical assistance to national bodies and individual facilities to adopt this best practice. This presentation will discuss security concepts that are implemented by the GTRI in cooperation with the Australian Nuclear Science and Technology Organization's Regional Security of Radioactive Sources Project. (author)

  15. Teaching Evaluation: Waiting for Initiatives

    Directory of Open Access Journals (Sweden)

    Alejandro Canales Sánchez

    2008-08-01

    Full Text Available In this text, it is sustained that, despite the fact that the teaching activity is one of the main functions of higher education institutions or even the only one in most of them, it hasn’t been reflected in the leading initiatives that have been set in motion in this area for the last two decades. In particular, it points out that the wide evaluation politics established in the education system during the late eighties, didn’t consider the teaching activity as a concern issue for the mechanisms or rewards in the evaluation system. Even though the implementation of new actions tried to repair the situation, mainly by improving the quality of working time and the qualifications of the personnel performing these activities; teaching, in strict sense, and the design or application of a new evaluation scheme to strengthen it, didn’t get better.

  16. Somerset County Renewable Energy Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Katula, Denise [County of Somerset, Somervile, NJ (United States)

    2014-05-07

    The County of Somerset, New Jersey, through the Somerset County Improvement Authority (SCIA), applied Federal funding through the U.S. Department of Energy to will apply project funds to buy-down the capital costs of equipment associated with the installation of solar photovoltaic (PV) systems at two sites owned by the County. This Renewable Energy Initiative allows the County to take advantage of clean renewable energy, without any adverse debt impacts, and at a price that results in operating budget savings beyond what is presently available in the marketplace. This project addressed the objectives of the Office of Energy Efficiency and Renewable Energy by making the acquisition of renewable energy more affordable for the County, thereby, encouraging other counties and local units to develop similar programs and increase the deployment of solar energy technologies. The two sites that were funded by the DOE grant are part of a much larger, ambitious, and unique renewable energy project, described in the next section.

  17. Plug-in Hybrid Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Goodman, Angie; Moore, Ray; Rowden, Tim

    2013-09-27

    Our main project objective was to implement Plug-in Electric Vehicles (PEV) and charging infrastructure into our electric distribution service territory and help reduce barriers in the process. Our research demonstrated the desire for some to be early adopters of electric vehicles and the effects lack of education plays on others. The response of early adopters was tremendous: with the initial launch of our program we had nearly 60 residential customers interested in taking part in our program. However, our program only allowed for 15 residential participants. Our program provided assistance towards purchasing a PEV and installation of Electric Vehicle Supply Equipment (EVSE). The residential participants have all come to love their PEVs and are more than enthusiastic about promoting the many benefits of driving electric.

  18. Initial performance parameters on FXR

    International Nuclear Information System (INIS)

    Kulke, B.; Innes, T.G.; Kihara, R.; Scarpetti, R.D.

    1982-01-01

    Construction of the new flash x-ray induction LINAC (FXR) at Lawrence Livermore National Laboratory has been completed. Initial tuning of the machine has produced stable current pulses in excess of 2 kA at the design energy of 20 MeV, with an 80 ns FWHM pulse width, producing single-pulse radiation doses near 500 Roentgen at one meter from the target. The electronic spot size on the bremsstrahlung target is estimated at 3 to 5 mm. In this paper we will discuss the basic FXR design; running-in and tuning of the machine; emittance measurements; beam stability; switch gap synchronization; and measurements of the radiation dose and angular distribution

  19. Micmac Strategic Energy Planning Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Fred Corey

    2007-02-02

    In February 2005 the Aroostook Band of Micmacs submitted a grant application to the U.S. Department of Energy’s (DOE) Tribal First Steps Program. The purpose of the application was to request funding and technical assistance to identify and document Tribal energy issues, develop a Tribal energy vision, evaluate potential energy opportunities, and to develop an action plan for future Tribal energy activities. The grant application was subsequently funded by DOE, and the Aroostook Band of Micmacs hired an energy consultant to assist with completion of the project. In addition to identification and documentation of Tribal energy issues, and the development of a Tribal energy vision, the potential for wind energy development on Tribal land, and residential energy efficiency issues were thoroughly evaluated.

  20. Cultural initiation of medical doctors.

    Science.gov (United States)

    Zsinkó-Szabó, Zoltán; Lázár, Imre

    2013-12-01

    Eighteen years experience of teaching medical anthropology at a Hungarian medical school offers insight into the dynamics of interference between the rationalist epistemological tradition of biomedicine as one of the central paradigms of modernism and the cultural relativism of medical anthropology, as cultural anthropology is considered to be one of the generators of postmodern thinking. Tracing back the informal "prehistory" of our Institute, we can reveal its psychosomatic, humanistic commitment and critical basis as having represented a kind of counterculture compared with the technocrats of state-socialist Hungary's health ideology. The historical change and socio-cultural transition in Hungary after 1989 was accompanied by changes in the medical system as well as in philosophy and in the structure of the teaching of social sciences. The developing pluralism in the medical system together with the pluralism of social ideologies allowed the substitution of the dogmatic Marxist-Leninist framework with the more pragmatic and empiricist behavioral sciences including medical sociology and medical anthropology. The conflict between the initiation function of the hard preclinical training of the first two years, and the reflective, relativistic and critical narrative on "biomedicine as culture bound entity" constructed by medical anthropology during the second year of medical training is discussed. We also submit our fieldwork data gained as a result of a two year investigation period focusing on diverse initiation types of "would be" physicians. The main proportion of our data derives from individual semi structured deep interviews together with focus group interviews carried out with medical students of upper years. Finally, the role of medical anthropology in the "rite of passage" of becoming a medical doctor is summarized, paying attention to their field work reports and the risks and gains in this process.

  1. The Barroso Initiative: Window Dressing or Democracy Boost?

    Directory of Open Access Journals (Sweden)

    Davor Jančić

    2012-01-01

    Full Text Available This article carries out a multifaceted legal analysis of the so-called Barroso Initiative, which was commenced by the European Commission in September 2006 in order to involve national parliaments of the Member States in the process of EU policy making. The key motive underlying the Initiative is to enhance the parliamentary and democratic dimension of the Union. After examining the origins, nature, scope and purpose of the Initiative, we explain the distinction between the Barroso Initiative and the early warning mechanism. In an attempt to assess the practical effects of the Initiative, we probe into its operation and reception in the national parliaments of France, the United Kingdom and Portugal, as systems which represent different constitutional and political traditions and which thus exhibit different attitudes to European scrutiny. In particular, we inquire about the constitutional impact of the Initiative on the national parliament in question. The paper concludes that the Barroso Initiative is a welcome commitment whose potential for eradicating the democratic deficit is modest but nonetheless one worth actively engaging in.

  2. Initiating Event Analysis of a Lithium Fluoride Thorium Reactor

    Science.gov (United States)

    Geraci, Nicholas Charles

    The primary purpose of this study is to perform an Initiating Event Analysis for a Lithium Fluoride Thorium Reactor (LFTR) as the first step of a Probabilistic Safety Assessment (PSA). The major objective of the research is to compile a list of key initiating events capable of resulting in failure of safety systems and release of radioactive material from the LFTR. Due to the complex interactions between engineering design, component reliability and human reliability, probabilistic safety assessments are most useful when the scope is limited to a single reactor plant. Thus, this thesis will study the LFTR design proposed by Flibe Energy. An October 2015 Electric Power Research Institute report on the Flibe Energy LFTR asked "what-if?" questions of subject matter experts and compiled a list of key hazards with the most significant consequences to the safety or integrity of the LFTR. The potential exists for unforeseen hazards to pose additional risk for the LFTR, but the scope of this thesis is limited to evaluation of those key hazards already identified by Flibe Energy. These key hazards are the starting point for the Initiating Event Analysis performed in this thesis. Engineering evaluation and technical study of the plant using a literature review and comparison to reference technology revealed four hazards with high potential to cause reactor core damage. To determine the initiating events resulting in realization of these four hazards, reference was made to previous PSAs and existing NRC and EPRI initiating event lists. Finally, fault tree and event tree analyses were conducted, completing the logical classification of initiating events. Results are qualitative as opposed to quantitative due to the early stages of system design descriptions and lack of operating experience or data for the LFTR. In summary, this thesis analyzes initiating events using previous research and inductive and deductive reasoning through traditional risk management techniques to

  3. Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells

    Energy Technology Data Exchange (ETDEWEB)

    Ge, Yuqing; Zhou, Fengbiao; Chen, Hong; Cui, Chunhong; Liu, Dan [Key Laboratory of Glycoconjuates Research, Ministry of Public Health and Gene Research Center, Shanghai Medical College of Fudan University, Shanghai 200032 (China); Li, Qiuping [Zhongshan Hospital of Fudan University, Shanghai 200032 (China); Yang, Zhiyuan; Wu, Guoqiang [Key Laboratory of Glycoconjuates Research, Ministry of Public Health and Gene Research Center, Shanghai Medical College of Fudan University, Shanghai 200032 (China); Sun, Shuhui [Key Laboratory of Medical Molecular Virology, Ministry of Education and Health, Shanghai Medical College of Fudan University, Shanghai 200032 (China); Gu, Jianxin [Key Laboratory of Glycoconjuates Research, Ministry of Public Health and Gene Research Center, Shanghai Medical College of Fudan University, Shanghai 200032 (China); Institutes of Biomedical Sciences of Fudan University, Shanghai 200032 (China); Wei, Yuanyan, E-mail: yywei@fudan.edu.cn [Key Laboratory of Glycoconjuates Research, Ministry of Public Health and Gene Research Center, Shanghai Medical College of Fudan University, Shanghai 200032 (China); Jiang, Jianhai, E-mail: jianhaijiang@fudan.edu.cn [Key Laboratory of Glycoconjuates Research, Ministry of Public Health and Gene Research Center, Shanghai Medical College of Fudan University, Shanghai 200032 (China)

    2010-07-09

    Sox2, a master transcription factor, contributes to the generation of induced pluripotent stem cells and plays significant roles in sustaining the self-renewal of neural stem cells and glioma-initiating cells. Understanding the functional differences of Sox2 between glioma-initiating cells and normal neural stem cells would contribute to therapeutic approach for treatment of brain tumors. Here, we first demonstrated that Sox2 could contribute to the self-renewal and proliferation of glioma-initiating cells. The following experiments showed that Sox2 was activated at translational level in a subset of human glioma-initiating cells compared with the normal neural stem cells. Further investigation revealed there was a positive correlation between Sox2 and eukaryotic initiation factor 4E (eIF4E) in glioma tissues. Down-regulation of eIF4E decreased Sox2 protein level without altering its mRNA level in glioma-initiating cells, indicating that Sox2 was activated by eIF4E at translational level. Furthermore, eIF4E was presumed to regulate the expression of Sox2 by its 5' untranslated region (5' UTR) sequence. Our results suggest that the eIF4E-Sox2 axis is a novel mechanism of unregulated self-renewal of glioma-initiating cells, providing a potential therapeutic target for glioma.

  4. Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells

    International Nuclear Information System (INIS)

    Ge, Yuqing; Zhou, Fengbiao; Chen, Hong; Cui, Chunhong; Liu, Dan; Li, Qiuping; Yang, Zhiyuan; Wu, Guoqiang; Sun, Shuhui; Gu, Jianxin; Wei, Yuanyan; Jiang, Jianhai

    2010-01-01

    Sox2, a master transcription factor, contributes to the generation of induced pluripotent stem cells and plays significant roles in sustaining the self-renewal of neural stem cells and glioma-initiating cells. Understanding the functional differences of Sox2 between glioma-initiating cells and normal neural stem cells would contribute to therapeutic approach for treatment of brain tumors. Here, we first demonstrated that Sox2 could contribute to the self-renewal and proliferation of glioma-initiating cells. The following experiments showed that Sox2 was activated at translational level in a subset of human glioma-initiating cells compared with the normal neural stem cells. Further investigation revealed there was a positive correlation between Sox2 and eukaryotic initiation factor 4E (eIF4E) in glioma tissues. Down-regulation of eIF4E decreased Sox2 protein level without altering its mRNA level in glioma-initiating cells, indicating that Sox2 was activated by eIF4E at translational level. Furthermore, eIF4E was presumed to regulate the expression of Sox2 by its 5' untranslated region (5' UTR) sequence. Our results suggest that the eIF4E-Sox2 axis is a novel mechanism of unregulated self-renewal of glioma-initiating cells, providing a potential therapeutic target for glioma.

  5. Vicious walkers in a potential

    International Nuclear Information System (INIS)

    Bray, Alan J; Winkler, Karen

    2004-01-01

    We consider N vicious walkers moving in one dimension in a one-body potential v(x). Using the backward Fokker-Planck equation we derive exact results for the asymptotic form of the survival probability Q(x, t) of vicious walkers initially located at (x 1 , ..., x N ) = x, when v(x) is an arbitrary attractive potential. Explicit results are given for a square-well potential with absorbing or reflecting boundary conditions at the walls, and for a harmonic potential with an absorbing or reflecting boundary at the origin and the walkers starting on the positive half line. By mapping the problem of N vicious walkers in zero potential onto the harmonic potential problem, we rederive the results by Fisher (1984 J. Stat. Phys. 34 667) and Krattenthaler et al (2000 J. Phys. A: Math. Gen. 33 8835) respectively for vicious walkers on an infinite line and on a semi-infinite line with an absorbing wall at the origin. This mapping also gives a new result for vicious walkers on a semi-infinite line with a reflecting boundary at the origin: Q(x,t) ∼ t N(N-1)/2

  6. Initial report of the osteogenesis imperfecta adult natural history initiative.

    Science.gov (United States)

    Tosi, Laura L; Oetgen, Matthew E; Floor, Marianne K; Huber, Mary Beth; Kennelly, Ann M; McCarter, Robert J; Rak, Melanie F; Simmonds, Barbara J; Simpson, Melissa D; Tucker, Carole A; McKiernan, Fergus E

    2015-11-14

    A better understanding of the natural history of osteogenesis imperfecta (OI) in adulthood should improve health care for patients with this rare condition. The Osteogenesis Imperfecta Foundation established the Adult Natural History Initiative (ANHI) in 2010 to give voice to the health concerns of the adult OI community and to begin to address existing knowledge gaps for this condition. Using a web-based platform, 959 adults with self-reported OI, representing a wide range of self-reported disease severity, reported symptoms and health conditions, estimated the impact of these concerns on present and future health-related quality of life (QoL) and completed a Patient-Reported Outcomes Measurement Information System (PROMIS®) survey of health issues. Adults with OI report lower general physical health status (p report generally similar mental health status. Musculoskeletal, auditory, pulmonary, endocrine, and gastrointestinal issues are particular future health-related QoL concerns for these adults. Numerous other statistically significant differences exist among adults with OI as well as between adults with OI and the referent PROMIS® population, but the clinical significance of these differences is uncertain. Adults with OI report lower general health status but are otherwise more similar to the general population than might have been expected. While reassuring, further analysis of the extensive OI-ANHI databank should help identify areas of unique clinical concern and for future research. The OI-ANHI survey experience supports an internet-based strategy for successful patient-centered outcomes research in rare disease populations.

  7. Initial data sets for the Schwarzschild spacetime

    International Nuclear Information System (INIS)

    Gomez-Lobo, Alfonso Garcia-Parrado; Kroon, Juan A. Valiente

    2007-01-01

    A characterization of initial data sets for the Schwarzschild spacetime is provided. This characterization is obtained by performing a 3+1 decomposition of a certain invariant characterization of the Schwarzschild spacetime given in terms of concomitants of the Weyl tensor. This procedure renders a set of necessary conditions--which can be written in terms of the electric and magnetic parts of the Weyl tensor and their concomitants--for an initial data set to be a Schwarzschild initial data set. Our approach also provides a formula for a static Killing initial data set candidate--a KID candidate. Sufficient conditions for an initial data set to be a Schwarzschild initial data set are obtained by supplementing the necessary conditions with the requirement that the initial data set possesses a stationary Killing initial data set of the form given by our KID candidate. Thus, we obtain an algorithmic procedure of checking whether a given initial data set is Schwarzschildean or not

  8. Simulation of Initiation in Hexanitrostilbene

    Science.gov (United States)

    Thompson, Aidan; Shan, Tzu-Ray; Yarrington, Cole; Wixom, Ryan

    We report on the effect of isolated voids and pairs of nearby voids on hot spot formation, growth and chemical reaction initiation in hexanitrostilbene (HNS) crystals subjected to shock loading. Large-scale, reactive molecular dynamics simulations are performed using the reactive force field (ReaxFF) as implemented in the LAMMPS software. The ReaxFF force field description for HNS has been validated previously by comparing the isothermal equation of state to available diamond anvil cell (DAC) measurements and density function theory (DFT) calculations. Micron-scale molecular dynamics simulations of a supported shockwave propagating in HNS crystal along the [010] orientation are performed (up = 1.25 km/s, Us =4.0 km/s, P = 11GPa.) We compare the effect on hot spot formation and growth rate of isolated cylindrical voids up to 0.1 µm in size with that of two 50nm voids set 100nm apart. Results from the micron-scale atomistic simulations are compared with hydrodynamics simulations. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lock- heed Martin Corporation, for the U.S. DOE National Nuclear Security Administration under Contract DE-AC04-94AL85000.

  9. Clean coal initiatives in Indiana

    Science.gov (United States)

    Bowen, B.H.; Irwin, M.W.; Sparrow, F.T.; Mastalerz, Maria; Yu, Z.; Kramer, R.A.

    2007-01-01

    Purpose - Indiana is listed among the top ten coal states in the USA and annually mines about 35 million short tons (million tons) of coal from the vast reserves of the US Midwest Illinois Coal Basin. The implementation and commercialization of clean coal technologies is important to the economy of the state and has a significant role in the state's energy plan for increasing the use of the state's natural resources. Coal is a substantial Indiana energy resource and also has stable and relatively low costs, compared with the increasing costs of other major fuels. This indigenous energy source enables the promotion of energy independence. The purpose of this paper is to outline the significance of clean coal projects for achieving this objective. Design/methodology/approach - The paper outlines the clean coal initiatives being taken in Indiana and the research carried out at the Indiana Center for Coal Technology Research. Findings - Clean coal power generation and coal for transportation fuels (coal-to-liquids - CTL) are two major topics being investigated in Indiana. Coking coal, data compilation of the bituminous coal qualities within the Indiana coal beds, reducing dependence on coal imports, and provision of an emissions free environment are important topics to state legislators. Originality/value - Lessons learnt from these projects will be of value to other states and countries.

  10. Electrical initiation of an energetic nanolaminate film

    Science.gov (United States)

    Tringe, Joseph W.; Gash, Alexander E.; Barbee, Jr., Troy W.

    2010-03-30

    A heating apparatus comprising an energetic nanolaminate film that produces heat when initiated, a power source that provides an electric current, and a control that initiates the energetic nanolaminate film by directing the electric current to the energetic nanolaminate film and joule heating the energetic nanolaminate film to an initiation temperature. Also a method of heating comprising providing an energetic nanolaminate film that produces heat when initiated, and initiating the energetic nanolaminate film by directing an electric current to the energetic nanolaminate film and joule heating the energetic nanolaminate film to an initiation temperature.

  11. Final Report: Multi-State Sharing Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Begoli, Edmon [ORNL; Boehmann, Brant [ORNL; DeNap, Frank A [ORNL

    2012-04-01

    In 2003 a joint effort between the U.S. Department of Homeland Security (DHS) and the U.S. Department of Justice created state and metropolitan intelligence fusion centers. These fusion centers were an effort to share law enforcement, disaster, and terrorism related information and intelligence between state and local jurisdictions and to share terrorism related intelligence between state and local law enforcement agencies and various federal entities. In 2006, DHS commissioned the Oak Ridge National Laboratory to establish and manage a groundbreaking program to assist local, state, and tribal leaders in developing the tools and methods required to anticipate and forestall terrorist events and to enhance disaster response. This program, called the Southeast Region Research Initiative (SERRI), combines science and technology with validated operational approaches to address regionally unique requirements and suggest regional solutions with the potential for national application. In 2009, SERRI sponsored the Multistate Sharing Initiative (MSSI) to assist state and metropolitan intelligence fusion centers with sharing information related to a wider variety of state interests than just terrorism. While these fusion centers have been effective at sharing data across organizations within their respective jurisdictions, their organizational structure makes bilateral communication with federal entities convenient and also allows information to be further disbursed to other local entities when appropriate. The MSSI-developed Suspicious Activity Report (SAR) sharing system allows state-to-state sharing of non-terrorism-related law enforcement and disaster information. Currently, the MSSI SAR system is deployed in Alabama, Kentucky, Tennessee, and South Carolina. About 1 year after implementation, cognizant fusion center personnel from each state were contacted to ascertain the status of their MSSI SAR systems. The overwhelming response from these individuals was that the MSSI

  12. Nested Potential Games

    OpenAIRE

    Hiroshi Uno

    2007-01-01

    This paper proposes a new class of potential games, the nested potential games, which generalize the potential games defined in Monderer and Shapley (1996), as well as the pseudo-potential games defined in Dubey et al. (2006). We show that each maximizer of a nested potential is a Nash equilibrium.

  13. Initiation at closely spaced replication origins in a yeast chromosome.

    Science.gov (United States)

    Brewer, B J; Fangman, W L

    1993-12-10

    Replication of eukaryotic chromosomes involves initiation at origins spaced an average of 50 to 100 kilobase pairs. In yeast, potential origins can be recognized as autonomous replication sequences (ARSs) that allow maintenance of plasmids. However, there are more ARS elements than active chromosomal origins. The possibility was examined that close spacing of ARSs can lead to inactive origins. Two ARSs located 6.5 kilobase pairs apart can indeed interfere with each other. Replication is initiated from one or the other ARS with equal probability, but rarely (< 5%) from both ARSs on the same DNA molecule.

  14. Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus

    Directory of Open Access Journals (Sweden)

    Say-Tin Yeap

    2008-04-01

    Full Text Available Macrophage activation syndrome (MAS is known to be a severe and potentially life-threatening complication of rheumatic disorder, especially systemic juvenile rheumatoid arthritis. It is very rare for MAS to be an initial presentation of systemic lupus erythematosus (SLE. Here, we report a 14-year-old girl in whom MAS developed as an initial presentation of SLE. With early diagnosis and administration of cyclosporine A, she had a fair outcome. Further testing showed positive anti-dsDNA about 8 months later.

  15. Initial frequency shift of large amplitude plasma wave, 2

    International Nuclear Information System (INIS)

    Yamanaka, K.; Sugihara, R.; Ohsawa, Y.; Kamimura, T.

    1979-07-01

    A nonlinear complex frequency shift of the ion acoustic wave in the initial phase defined by 0 0 and ωsub(s)/k as long as ωsub(s) >> γsub( l), where phi 0 , ωsub(s), γsub( l) and t sub(c) are the initial value of the potential, the frequency of the wave, the linear Landau damping coefficient and the time for the first minimum of the amplitude oscillation, respectively. A simulation study is also carried out. The results confirm the validity of the theory. (author)

  16. Green corridor : energy efficiency initiatives

    Energy Technology Data Exchange (ETDEWEB)

    Bartlett, M.; Strickland, R.; Harding, N. [Windsor Univ., ON (Canada)

    2005-07-01

    This presentation discussed environmental sustainability using alternative energy technologies. It discussed Ecohouse, which is a house designed using conventional and inventive products and techniques to represent an eco-efficient model for living, a more sustainable house, demonstrating sustainable technologies in action and setting a new standard for resource efficiency in Windsor. The presentation provided a building analysis and discussed the following: geothermal heating; distributive power; green roof; net metering; grey water plumbing; solar water heating; passive lighting; energy efficient lighting and geothermal heating and cooling. It also discussed opportunities for innovation, namely: greenhouse; composting toilets; alternative insulation; net metering; solar arrays; hydroponics; and expansion of the house. Also discussed were a nature bridge, an underwater electric kite, and a vertically aerodynamic turbine. The benefits of renewable energy, small hydro power potential, and instream energy generation technology were presented. 9 refs., figs.

  17. Shock Initiation of Damaged Explosives

    Energy Technology Data Exchange (ETDEWEB)

    Chidester, S K; Vandersall, K S; Tarver, C M

    2009-10-22

    Explosive and propellant charges are subjected to various mechanical and thermal insults that can increase their sensitivity over the course of their lifetimes. To quantify this effect, shock initiation experiments were performed on mechanically and thermally damaged LX-04 (85% HMX, 15% Viton by weight) and PBX 9502 (95% TATB, 5% Kel-F by weight) to obtain in-situ manganin pressure gauge data and run distances to detonation at various shock pressures. We report the behavior of the HMX-based explosive LX-04 that was damaged mechanically by applying a compressive load of 600 psi for 20,000 cycles, thus creating many small narrow cracks, or by cutting wedge shaped parts that were then loosely reassembled, thus creating a few large cracks. The thermally damaged LX-04 charges were heated to 190 C for long enough for the beta to delta solid - solid phase transition to occur, and then cooled to ambient temperature. Mechanically damaged LX-04 exhibited only slightly increased shock sensitivity, while thermally damaged LX-04 was much more shock sensitive. Similarly, the insensitive explosive PBX 9502 was mechanically damaged using the same two techniques. Since PBX 9502 does not undergo a solid - solid phase transition but does undergo irreversible or 'rachet' growth when thermally cycled, thermal damage to PBX 9502 was induced by this procedure. As for LX-04, the thermally damaged PBX 9502 demonstrated a greater shock sensitivity than mechanically damaged PBX 9502. The Ignition and Growth reactive flow model calculated the increased sensitivities by igniting more damaged LX-04 and PBX 9502 near the shock front based on the measured densities (porosities) of the damaged charges.

  18. Process Engineering Technology Center Initiative

    Science.gov (United States)

    Centeno, Martha A.

    2002-01-01

    NASA's Kennedy Space Center (KSC) is developing as a world-class Spaceport Technology Center (STC). From a process engineering (PE) perspective, the facilities used for flight hardware processing at KSC are NASA's premier factories. The products of these factories are safe, successful shuttle and expendable vehicle launches carrying state-of-the-art payloads. PE is devoted to process design, process management, and process improvement, rather than product design. PE also emphasizes the relationships of workers with systems and processes. Thus, it is difficult to speak of having a laboratory for PE at K.S.C. because the entire facility is practically a laboratory when observed from a macro level perspective. However, it becomes necessary, at times, to show and display how K.S.C. has benefited from PE and how K.S.C. has contributed to the development of PE; hence, it has been proposed that a Process Engineering Technology Center (PETC) be developed to offer a place with a centralized focus on PE projects, and a place where K.S.C.'s PE capabilities can be showcased, and a venue where new Process Engineering technologies can be investigated and tested. Graphics for showcasing PE capabilities have been designed, and two initial test beds for PE technology research have been identified. Specifically, one test bed will look into the use of wearable computers with head mounted displays to deliver work instructions; the other test bed will look into developing simulation models that can be assembled into one to create a hierarchical model.

  19. Bioeconomy Initiative at MBI International

    Energy Technology Data Exchange (ETDEWEB)

    Kleff, Susanne, Ph.D.

    2011-11-30

    Di-carboxylic acids have the potential to replace petrochemicals used in the polymer industry (Werpy and Petersen, 2004). MBI developed a process for the production of succinic acid using a proprietary organism. During this work MBI assessed the feasibility to produce other carboxylic acids either using A. succinogenes or other organisms. The development of recombinant A. succinogenes strain derivatives for a mono-carboxylic acid through over-expression of enzymatic activities was successful. Fermentations achieved titers of 58 g/L for this organic acid. Recombinant strains that produced the same acid, but a different stereoisomer, reached titers of 10 g/L. Attempts to increase the titers for this isomer as well as other organic acids were unsuccessful. MBI is looking for commercial partners to pursue the development of recombinant A. succinogenes strains for the production of other organic acids. Attempts to develop recombinant strains of A. succinogenes for fumaric acid production through introduction of various antisense RNA constructs were unsuccessful. Alternative suitable organisms were evaluated and Rhizopus oryzae, a natural fumaric acid producer with potential for process improvements, was selected. A novel fermentation and one-step recovery process was developed that allowed capture of IP, produced titers of >80 g/L with a productivity of 1.8 g/L-h and 57% (g/g glucose) yield. The process was scaled to 2000 L pilot scale. The economic analysis projected a production cost of 72 c/lb. Recycling and re-use of the base was demonstrated and incorporated into the process. The ability of the organism to produce fumaric acid from other carbon sources and biomass hydrolysate was demonstrated. The production of other organic acids was evaluated and techno-economic de-risking roadmap documents were prepared.

  20. Interaction Effects of Happiness and Physical Activity on Smoking Initiation.

    Science.gov (United States)

    Torchyan, Armen A; BinSaeed, Abdulaziz A; Aleid, Yazeed S; Nagshbandi, Ahmed A; Almousa, Fahad; Papikyan, Satenik L; Gosadi, Ibrahim M

    2016-11-01

    Our aim was to assess the potential relationships among happiness, physical activity, and smoking initiation among undergraduate medical students in Saudi Arabia. We performed a cross-sectional study of randomly selected first- to fifth-year undergraduate medical students. Smoking initiation was defined as "ever trying smoking a cigarette, waterpipe, cigar/cigarillo, or other type of tobacco, even one or 2 puffs." The short scale Oxford Happiness Questionnaire was used to assess each student's happiness. Multivariate logistic regression analysis was performed. Of the 406 students surveyed (208 boys, 198 girls), 86 (21.1%) had initiated smoking. We found an interaction between physical activity (PA) and happiness on smoking initiation (p-interaction = .012). Among boys with low levels of PA, lower levels of happiness were associated with a greater likelihood of smoking initiation (OR = 5.8, 95%CI = 1.9 - 17.5). Also, high levels of PA increased the chance of smoking initiation among male students with high levels of happiness (OR = 5.6, 95%CI = 2.1 - 14.5). Our results suggest that young men with low levels of happiness and low levels of PA, as well as high levels of PA and high levels of happiness, may be targeted as a priority population in tobacco control intervention programs.