Irreducible complexity of iterated symmetric bimodal maps

Directory of Open Access Journals (Sweden)

J. P. Lampreia

2005-01-01

Full Text Available We introduce a tree structure for the iterates of symmetric bimodal maps and identify a subset which we prove to be isomorphic to the family of unimodal maps. This subset is used as a second factor for a ∗-product that we define in the space of bimodal kneading sequences. Finally, we give some properties for this product and study the ∗-product induced on the associated Markov shifts.

ISO27001 / ISO27002 a pocket guide

CERN Document Server

Calder, Alan

2013-01-01

Information is one of your organisation's most important resources. Keeping it secure is therefore vital to your business. This handy pocket guide is an essential overview of two key information security standards that cover the formal requirements (ISO27001:2013) for creating an Information Security Management System (ISMS), and the best-practice recommendations (ISO27002:2013) for those responsible for initiating, implementing or maintaining it.

A bimodal biometric identification system

Science.gov (United States)

Laghari, Mohammad S.; Khuwaja, Gulzar A.

2013-03-01

Biometrics consists of methods for uniquely recognizing humans based upon one or more intrinsic physical or behavioral traits. Physicals are related to the shape of the body. Behavioral are related to the behavior of a person. However, biometric authentication systems suffer from imprecision and difficulty in person recognition due to a number of reasons and no single biometrics is expected to effectively satisfy the requirements of all verification and/or identification applications. Bimodal biometric systems are expected to be more reliable due to the presence of two pieces of evidence and also be able to meet the severe performance requirements imposed by various applications. This paper presents a neural network based bimodal biometric identification system by using human face and handwritten signature features.

IsoBank workshop held at IsoEcol10 - University of Tokyo 2016

OpenAIRE

Hayden, Brian

2016-01-01

IsoBank is a repository for stable isotope values and relevant metadata. These slides were presented at a workshop held during IsoEcol10 to refine and design the IsoBank for the needs of a diverse group of researchers.

Aggressive Bimodal Communication in Domestic Dogs, Canis familiaris.

Science.gov (United States)

Déaux, Éloïse C; Clarke, Jennifer A; Charrier, Isabelle

2015-01-01

Evidence of animal multimodal signalling is widespread and compelling. Dogs' aggressive vocalisations (growls and barks) have been extensively studied, but without any consideration of the simultaneously produced visual displays. In this study we aimed to categorize dogs' bimodal aggressive signals according to the redundant/non-redundant classification framework. We presented dogs with unimodal (audio or visual) or bimodal (audio-visual) stimuli and measured their gazing and motor behaviours. Responses did not qualitatively differ between the bimodal and two unimodal contexts, indicating that acoustic and visual signals provide redundant information. We could not further classify the signal as 'equivalent' or 'enhancing' as we found evidence for both subcategories. We discuss our findings in relation to the complex signal framework, and propose several hypotheses for this signal's function.

Evaluation of the central libraries information security management at governmental universities located in Tehran, according to the international standard ISO/IEC 27002

Directory of Open Access Journals (Sweden)

Milad Malekolkalami

2014-02-01

Full Text Available This study assessed the evaluation of information security management status in central Libraries of governmental universities located in Tehran, according to ISO / I.E.C. 27002. Research method applied for the study is descriptive Survey and a questionnaire was used for collecting information. The questionnaire was distributed between the 74 central library managers of governmental universities in Tehran according to the recent list on the website of Ministry of Science, Research and Technology, that includes 39 components based on 11 indicators of the standard ISO/ I.E.C. 27002. Analysis of data has been done by using both descriptive and inferential statistics by Microsoft Excel 2007and SPSS statistical softwares. The results of research showed that the mean for libraries in 11 indexes are as follows: The mean for the first index, Security policy, is 3.91 , in the second index, organization of information security, is 4.23, in the third index, asset security management, is 4.38, in the fourth index, Human Resources Security management, is 4, in the fifth index, physical and environment Security management, is 4.07, in the sixth index, operations management and communications, is 4.15, in the Seventh index, access controls management, is 4.38, in the eighth index, information system acquisition, development and maintenance, is 3.92, in the ninth index, information security incident management, is 3.84, in the tenth index, business continuity management, is 3.46, in the eleventh index, compliance, is 3.69 that match with the standard ISO / IEC. 27002. The results of Research shown that totally mean for standard ISO/I.E.C. 27002 in the field of information security management in the central libraries, is 4 being in a good condition and there is no significant differences between the performance of the Central libraries of the governmental Universities in Tehran, since It is not observed significant difference between them in the field of

Aggressive Bimodal Communication in Domestic Dogs, Canis familiaris.

Directory of Open Access Journals (Sweden)

Éloïse C Déaux

Full Text Available Evidence of animal multimodal signalling is widespread and compelling. Dogs' aggressive vocalisations (growls and barks have been extensively studied, but without any consideration of the simultaneously produced visual displays. In this study we aimed to categorize dogs' bimodal aggressive signals according to the redundant/non-redundant classification framework. We presented dogs with unimodal (audio or visual or bimodal (audio-visual stimuli and measured their gazing and motor behaviours. Responses did not qualitatively differ between the bimodal and two unimodal contexts, indicating that acoustic and visual signals provide redundant information. We could not further classify the signal as 'equivalent' or 'enhancing' as we found evidence for both subcategories. We discuss our findings in relation to the complex signal framework, and propose several hypotheses for this signal's function.

Affective and physiological correlates of the perception of unimodal and bimodal emotional stimuli.

Science.gov (United States)

Rosa, Pedro J; Oliveira, Jorge; Alghazzawi, Daniyal; Fardoun, Habib; Gamito, Pedro

2017-08-01

Despite the multisensory nature of perception, previous research on emotions has been focused on unimodal emotional cues with visual stimuli. To the best of our knowledge, there is no evidence on the extent to which incongruent emotional cues from visual and auditory sensory channels affect pupil size. To investigate the effects of audiovisual emotional information perception on the physiological and affective response, but also to determine the impact of mismatched cues in emotional perception on these physiological indexes. Pupil size, electrodermal activity and affective subjective responses were recorded while 30 participants were exposed to visual and auditory stimuli with varied emotional content in three different experimental conditions: pictures and sounds presented alone (unimodal), emotionally matched audio-visual stimuli (bimodal congruent) and emotionally mismatched audio-visual stimuli (bimodal incongruent). The data revealed no effect of emotional incongruence on physiological and affective responses. On the other hand, pupil size covaried with skin conductance response (SCR), but the subjective experience was partially dissociated from autonomic responses. Emotional stimuli are able to trigger physiological responses regardless of valence, sensory modality or level of emotional congruence.

ISO radiation protection standards

International Nuclear Information System (INIS)

Becker, K.; West, N.

1981-01-01

After a brief description of the International Organization for Standardization (ISO) and its Technical Committee (TC) 85 ''Nuclear Energy'', the work of its Sub-Committee (SC) 2 ''Radiation Protection'' is described in some detail. Several international standards on subjects closely related to radiation protection have already been published, for example ISO-361 (Basic radiation protection symbol), ISO-1757 (Photographic dosimeters), ISO-1758 and 1759 (Direct and indirect-reading pocket exposure meters), ISO-2889 (Sampling of airborne radioactive materials), ISO-4037 (X and gamma reference radiations for calibration) and ISO-4071 (Testing of exposure meters and dosimeters). TC 85/SC 2 has currently eight active Working Groups (WG) dealing with 14 standards projects, mostly in advanced stages, in such fields as neutron and beta reference radiations, and X and gamma radiations of high and low dose-rates and high energies for calibration purposes, reference radiations for surface contamination apparatus, ejection systems for gamma radiography apparatus, industrial and laboratory irradiators, lead shielding units, protective clothing, thermoluminescence dosemeters, radioelement gauges, and surface contamination and decontamination. (author)

Bimodality and negative heat capacity in multifragmentation

International Nuclear Information System (INIS)

Tamain, B.; Bougault, R.; Lopez, O.; Pichon, M.

2003-01-01

This contribution addresses the question of the possible link between multifragmentation and the liquid-gas phase transition of nuclear matter. Bi-modality seems to be a robust signal of this link in the sense that theoretical calculations indicate that it is preserved even if a sizeable fraction of the available energy has not been shared among all the degrees of freedom. The corresponding measured properties are coherent with what is expected in a liquid-gas phase transition picture. Moreover, bi-modality and negative heat capacity are observed for the same set of events. (authors)

Asymmetric Bimodal Exponential Power Distribution on the Real Line

Directory of Open Access Journals (Sweden)

Mehmet Niyazi Çankaya

2018-01-01

Full Text Available The asymmetric bimodal exponential power (ABEP distribution is an extension of the generalized gamma distribution to the real line via adding two parameters that fit the shape of peakedness in bimodality on the real line. The special values of peakedness parameters of the distribution are a combination of half Laplace and half normal distributions on the real line. The distribution has two parameters fitting the height of bimodality, so capacity of bimodality is enhanced by using these parameters. Adding a skewness parameter is considered to model asymmetry in data. The location-scale form of this distribution is proposed. The Fisher information matrix of these parameters in ABEP is obtained explicitly. Properties of ABEP are examined. Real data examples are given to illustrate the modelling capacity of ABEP. The replicated artificial data from maximum likelihood estimates of parameters of ABEP and other distributions having an algorithm for artificial data generation procedure are provided to test the similarity with real data. A brief simulation study is presented.

Visualisation and characterisation of heterogeneous bimodal PDMS networks

DEFF Research Database (Denmark)

Bahrt, Frederikke; Daugaard, Anders Egede; Fleury, Clemence

2014-01-01

The existence of short-chain domains in heterogeneous bimodal PDMS networks has been confirmed visually, for the first time, through confocal fluorescence microscopy. The networks were prepared using a controlled reaction scheme where short PDMS chains were reacted below the gelation point...... bimodal networks with short-chain domains within a long-chain network. The average sizes of the short-chain domains were found to vary from 2.1 to 5.7 mm depending on the short-chain content. The visualised network structure could be correlated thereafter to the elastic properties, which were determined...... by rheology. All heterogeneous bimodal networks displayed significantly lower moduli than mono-modal PDMS elastomers prepared from the long polymer chains. Low-loss moduli as well as low-sol fractions indicate that low-elastic moduli can be obtained without compromising the network's structure...

ISO radiation sterilization standards

International Nuclear Information System (INIS)

Lambert, Byron J.; Hansen, Joyce M.

1998-01-01

This presentation provides an overview of the current status of the ISO radiation sterilization standards. The ISO standards are voluntary standards which detail both the validation and routine control of the sterilization process. ISO 11137 was approved in 1994 and published in 1995. When reviewing the standard you will note that less than 20% of the standard is devoted to requirements and the remainder is guidance on how to comply with the requirements. Future standards developments in radiation sterilization are being focused on providing additional guidance. The guidance that is currently provided in informative annexes of ISO 11137 includes: device/packaging materials, dose setting methods, and dosimeters and dose measurement, currently, there are four Technical Reports being developed to provide additional guidance: 1. AAMI Draft TIR, 'Radiation Sterilization Material Qualification' 2. ISO TR 13409-1996, 'Sterilization of health care products - Radiation sterilization - Substantiation of 25 kGy as a sterilization dose for small or infrequent production batches' 3. ISO Draft TR, 'Sterilization of health care products - Radiation sterilization Selection of a sterilization dose for a single production batch' 4. ISO Draft TR, 'Sterilization of health care products - Radiation sterilization-Product Families, Plans for Sampling and Frequency of Dose Audits'

Bimodal magmatism produced by progressively inhibited crustal assimilation 2 (PICA)

NARCIS (Netherlands)

Meade, F.C.; Troll, V.R.; Ellam, R.M.; Freda, C.; Font Morales, L.; Donaldson, C.H.; Klonowska, I.

2014-01-01

The origin of bimodal (mafic-felsic) rock suites is a fundamental question in volcanology. Here we use major and trace elements, high-resolution Sr, Nd and Pb isotope analyses, experimental petrology and thermodynamic modelling to investigate bimodal magmatism at the iconic Carlingford Igneous

Functionalized bimodal mesoporous silicas as carriers for controlled aspirin delivery

Science.gov (United States)

Gao, Lin; Sun, Jihong; Li, Yuzhen

2011-08-01

The bimodal mesoporous silica modified with 3-aminopropyltriethoxysilane was performed as the aspirin carrier. The samples' structure, drug loading and release profiles were characterized with X-ray diffraction, scanning electron microscopy, N 2 adsorption and desorption, Fourier transform infrared spectroscopy, TG analysis, elemental analysis and UV-spectrophotometer. For further exploring the effects of the bimodal mesopores on the drug delivery behavior, the unimodal mesoporous material MCM-41 was also modified as the aspirin carrier. Meantime, Korsmeyer-Peppas equation ft= ktn was employed to analyze the dissolution data in details. It is indicated that the bimodal mesopores are beneficial for unrestricted drug molecules diffusing and therefore lead to a higher loading and faster releasing than that of MCM-41. The results show that the aspirin delivery properties are influenced considerably by the mesoporous matrix, whereas the large pore of bimodal mesoporous silica is the key point for the improved controlled-release properties.

Accreditation - ISO/IEC 17025

Science.gov (United States)

Kaus, Rüdiger

This chapter gives the background on the accreditation of testing and calibration laboratories according to ISO/IEC 17025 and sets out the requirements of this international standard. ISO 15189 describes similar requirements especially tailored for medical laboratories. Because of these similarities ISO 15189 is not separately mentioned throughout this lecture.

Event-related potentials to visual, auditory, and bimodal (combined auditory-visual) stimuli.

Science.gov (United States)

Isoğlu-Alkaç, Ummühan; Kedzior, Karina; Keskindemirci, Gonca; Ermutlu, Numan; Karamursel, Sacit

2007-02-01

The purpose of this study was to investigate the response properties of event related potentials to unimodal and bimodal stimulations. The amplitudes of N1 and P2 were larger during bimodal evoked potentials (BEPs) than auditory evoked potentials (AEPs) in the anterior sites and the amplitudes of P1 were larger during BEPs than VEPs especially at the parieto-occipital locations. Responses to bimodal stimulation had longer latencies than responses to unimodal stimulation. The N1 and P2 components were larger in amplitude and longer in latency during the bimodal paradigm and predominantly occurred at the anterior sites. Therefore, the current bimodal paradigm can be used to investigate the involvement and location of specific neural generators that contribute to higher processing of sensory information. Moreover, this paradigm may be a useful tool to investigate the level of sensory dysfunctions in clinical samples.

Internal Audit Status For ISO 9001 And ISO/ IEC 17025 In Malaysian Nuclear Agency

International Nuclear Information System (INIS)

Fazila Said; Nurul Huda Mudri; Nik Arlina Ali

2012-01-01

The development of MS ISO 9001 and MS ISO/ IEC 17025 in Malaysian Nuclear Agency is the basic step to enhance and improve the Quality Management System (QMS) for processes and laboratories that involve customers and suppliers in delivering products and services. The effectiveness of QMS is monitored by Research and Innovation Management Centre (RIMC) to ensure that all activities related to audit such as Internal Audit are well organized and implemented as documented in quality manual and procedure. This paper will discuss the status of internal audit for processes that implement MS ISO 9001 and laboratories that accredited with MS/ ISO IEC 17025 in year 2008, 2009 and 2010. The total of non-conformance (nc) and opportunity for improvement (ofi) for processes and laboratories and their numbers as per clause in MS ISO 9001 and MS ISO/ IEC 17025 are the indicators that reflects the effectiveness of QMS. Then, the total effectiveness of QMS for MS 9001 and MS ISO/ IEC 17025 is also determined via the number of conformance clause versus non-conformance clause for those three years. (author)

Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean

Energy Technology Data Exchange (ETDEWEB)

Razooky, Brandon S. [Rockefeller Univ., New York, NY (United States). Lab. of Virology and Infectious Disease; Gladstone Institutes (Virology and Immunology), San Francisco, CA (United States); Univ. of California, San Francisco, CA (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Center for Nanophase Materials Science (CNMS); Univ. of Tennessee, Knoxville, TN (United States). Bredesen Center for Interdisciplinary; Cao, Youfang [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hansen, Maike M. K. [Gladstone Institutes (Virology and Immunology), San Francisco, CA (United States); Perelson, Alan S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Simpson, Michael L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Center for Nanophase Materials Science (CNMS); Univ. of Tennessee, Knoxville, TN (United States). Bredesen Center for Interdisciplinary; Weinberger, Leor S. [Gladstone Institutes (Virology and Immunology), San Francisco, CA (United States); Univ. of California, San Francisco, CA (United States). Dept. of Biochemistry and Biophysics; Univ. of California, San Francisco, CA (United States). QB3: California Inst. of Quantitative Biosciences; Univ. of California, San Francisco, CA (United States). Dept. of Pharmaceutical Chemistry

2017-10-18

Fundamental to biological decision-making is the ability to generate bimodal expression patterns where two alternate expression states simultaneously exist. Here in this study, we use a combination of single-cell analysis and mathematical modeling to examine the sources of bimodality in the transcriptional program controlling HIV’s fate decision between active replication and viral latency. We find that the HIV Tat protein manipulates the intrinsic toggling of HIV’s promoter, the LTR, to generate bimodal ON-OFF expression, and that transcriptional positive feedback from Tat shifts and expands the regime of LTR bimodality. This result holds for both minimal synthetic viral circuits and full-length virus. Strikingly, computational analysis indicates that the Tat circuit’s non-cooperative ‘non-latching’ feedback architecture is optimized to slow the promoter’s toggling and generate bimodality by stochastic extinction of Tat. In contrast to the standard Poisson model, theory and experiment show that non-latching positive feedback substantially dampens the inverse noise-mean relationship to maintain stochastic bimodality despite increasing mean-expression levels. Given the rapid evolution of HIV, the presence of a circuit optimized to robustly generate bimodal expression appears consistent with the hypothesis that HIV’s decision between active replication and latency provides a viral fitness advantage. More broadly, the results suggest that positive-feedback circuits may have evolved not only for signal amplification but also for robustly generating bimodality by decoupling expression fluctuations (noise) from mean expression levels.

A HYPOTHESIS FOR THE COLOR BIMODALITY OF JUPITER TROJANS

Energy Technology Data Exchange (ETDEWEB)

Wong, Ian; Brown, Michael E., E-mail: iwong@caltech.edu [Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125 (United States)

2016-10-01

One of the most enigmatic and hitherto unexplained properties of Jupiter Trojans is their bimodal color distribution. This bimodality is indicative of two sub-populations within the Trojans, which have distinct size distributions. In this paper, we present a simple, plausible hypothesis for the origin and evolution of the two Trojan color sub-populations. In the framework of dynamical instability models of early solar system evolution, which suggest a common primordial progenitor population for both Trojans and Kuiper Belt objects, we use observational constraints to assert that the color bimodalities evident in both minor body populations developed within the primordial population prior to the onset of instability. We show that, beginning with an initial composition of rock and ices, location-dependent volatile loss through sublimation in this primordial population could have led to sharp changes in the surface composition with heliocentric distance. We propose that the depletion or retention of H{sub 2}S ice on the surface of these objects was the key factor in creating an initial color bimodality. Objects that retained H{sub 2}S on their surfaces developed characteristically redder colors upon irradiation than those that did not. After the bodies from the primordial population were scattered and emplaced into their current positions, they preserved this primordial color bimodality to the present day. We explore predictions of the volatile loss model—in particular, the effect of collisions within the Trojan population on the size distributions of the two sub-populations—and propose further experimental and observational tests of our hypothesis.

A HYPOTHESIS FOR THE COLOR BIMODALITY OF JUPITER TROJANS

International Nuclear Information System (INIS)

Wong, Ian; Brown, Michael E.

2016-01-01

One of the most enigmatic and hitherto unexplained properties of Jupiter Trojans is their bimodal color distribution. This bimodality is indicative of two sub-populations within the Trojans, which have distinct size distributions. In this paper, we present a simple, plausible hypothesis for the origin and evolution of the two Trojan color sub-populations. In the framework of dynamical instability models of early solar system evolution, which suggest a common primordial progenitor population for both Trojans and Kuiper Belt objects, we use observational constraints to assert that the color bimodalities evident in both minor body populations developed within the primordial population prior to the onset of instability. We show that, beginning with an initial composition of rock and ices, location-dependent volatile loss through sublimation in this primordial population could have led to sharp changes in the surface composition with heliocentric distance. We propose that the depletion or retention of H 2 S ice on the surface of these objects was the key factor in creating an initial color bimodality. Objects that retained H 2 S on their surfaces developed characteristically redder colors upon irradiation than those that did not. After the bodies from the primordial population were scattered and emplaced into their current positions, they preserved this primordial color bimodality to the present day. We explore predictions of the volatile loss model—in particular, the effect of collisions within the Trojan population on the size distributions of the two sub-populations—and propose further experimental and observational tests of our hypothesis.

Food service compliance with ISO 14001 and ISO 22000

Directory of Open Access Journals (Sweden)

Laura Lyra Santos

2012-06-01

Full Text Available OBJECTIVE: The objective of this study was to assess food service environmental and food safety management systems according to two checklists based on ABNT ISO 22000 and 14001. METHODS: This exploratory and descriptive study investigated a-la-carte food services of the Federal District, Brazil. Two checklists were developed to investigate ISO 14001 and 22000 compliance. A total of 37 food services were selected from the list of the Brazilian Association of Bars and Restaurants by simple random sampling. Checklist results were analyzed according to ANVISA resolution nº 275/2002. RESULTS: Only five food services employed dietitians to supervise meal production. These establishments achieved the highest ISO compliance. However, no establishment had more than 50% ISO 14001 or 22000 compliance. Restaurants showed little concern for the environment and disobeyed waste disposal laws by not separating recyclables from non-recyclables. CONCLUSION: The study food services do not have safe meal production systems, evidenced by non-conformity with the reference standards. Additionally, they do not attempt to reduce the environmental impact of their wastes. Food services supervised by dietitians are better prepared to produce safe foods.

BDVC (Bimodal Database of Violent Content): A database of violent audio and video

Science.gov (United States)

Rivera Martínez, Jose Luis; Mijes Cruz, Mario Humberto; Rodríguez Vázqu, Manuel Antonio; Rodríguez Espejo, Luis; Montoya Obeso, Abraham; García Vázquez, Mireya Saraí; Ramírez Acosta, Alejandro Álvaro

2017-09-01

Nowadays there is a trend towards the use of unimodal databases for multimedia content description, organization and retrieval applications of a single type of content like text, voice and images, instead bimodal databases allow to associate semantically two different types of content like audio-video, image-text, among others. The generation of a bimodal database of audio-video implies the creation of a connection between the multimedia content through the semantic relation that associates the actions of both types of information. This paper describes in detail the used characteristics and methodology for the creation of the bimodal database of violent content; the semantic relationship is stablished by the proposed concepts that describe the audiovisual information. The use of bimodal databases in applications related to the audiovisual content processing allows an increase in the semantic performance only and only if these applications process both type of content. This bimodal database counts with 580 audiovisual annotated segments, with a duration of 28 minutes, divided in 41 classes. Bimodal databases are a tool in the generation of applications for the semantic web.

ISO 9000

International Nuclear Information System (INIS)

Graham, J.F.

1992-01-01

The European Community has adopted the Single European Act. The act states that in order to do business in Europe after 1992, a supplied is expected to be ISO 9000 registered. This paper reports on ISO 9000, which is a systematic approach to implementing a quality system. It is not in the category of technical or product standards, but a standard relating to management of quality in that sector of a company seeking registration. If a company is already systematically practicing quality improvement, these efforts will be applicable to the ISO 9000 certification process. A company will need to refine and update procedures and develop a quality manual. An internal auditing and a corrective action system will also have to be established. The latter addresses audit results, customer complaints, quality system problems, and internal quality improvement suggestions

Speech Recognition and Cognitive Skills in Bimodal Cochlear Implant Users

Science.gov (United States)

Hua, Håkan; Johansson, Björn; Magnusson, Lennart; Lyxell, Björn; Ellis, Rachel J.

2017-01-01

Purpose: To examine the relation between speech recognition and cognitive skills in bimodal cochlear implant (CI) and hearing aid users. Method: Seventeen bimodal CI users (28-74 years) were recruited to the study. Speech recognition tests were carried out in quiet and in noise. The cognitive tests employed included the Reading Span Test and the…

Measuring oxygen uptake in fishes with bimodal respiration.

Science.gov (United States)

Lefevre, S; Bayley, M; McKenzie, D J

2016-01-01

Respirometry is a robust method for measurement of oxygen uptake as a proxy for metabolic rate in fishes, and how species with bimodal respiration might meet their demands from water v. air has interested researchers for over a century. The challenges of measuring oxygen uptake from both water and air, preferably simultaneously, have been addressed in a variety of ways, which are briefly reviewed. These methods are not well-suited for the long-term measurements necessary to be certain of obtaining undisturbed patterns of respiratory partitioning, for example, to estimate traits such as standard metabolic rate. Such measurements require automated intermittent-closed respirometry that, for bimodal fishes, has only recently been developed. This paper describes two approaches in enough detail to be replicated by the interested researcher. These methods are for static respirometry. Measuring oxygen uptake by bimodal fishes during exercise poses specific challenges, which are described to aid the reader in designing experiments. The respiratory physiology and behaviour of air-breathing fishes is very complex and can easily be influenced by experimental conditions, and some general considerations are listed to facilitate the design of experiments. Air breathing is believed to have evolved in response to aquatic hypoxia and, probably, associated hypercapnia. The review ends by considering what realistic hypercapnia is, how hypercapnic tropical waters can become and how this might influence bimodal animals' gas exchange. © 2015 The Fisheries Society of the British Isles.

USGIN ISO metadata profile

Science.gov (United States)

Richard, S. M.

2011-12-01

content. The use cases for the detailed content must be well understood, and the degree of metadata complexity should be determined by requirements for those use cases. The ISO standard provides sufficient flexibility that relatively simple metadata records can be created that will serve for text-indexed search/discovery, resource evaluation by a user reading text content from the metadata, and access to the resource via http, ftp, or well-known service protocols (e.g. Thredds; OGC WMS, WFS, WCS).

Tinjauan Kritis Terhadap Implementasi Iso 9000

OpenAIRE

Purnama, Nursya’bani

2005-01-01

ISO 9000 telah diterima secara luas sebagai acuan sistem manajemen kualitas dan penjaminan kualitas. Perusahaan-Perusahaan yang memperoleh sertifikasi ISO dari tahun ke ke tahun mengalami pertumbu¬han yang pesat. Dengan implementasi dan memperoleh sertifikasi ISO 9000, banyak Perusahaan di dunia mem¬peroleh peningkatan kinerja. Meskipun demikian, implementasi ISO 9000 juga dihadapkan pada sejumlah ham¬batan. Implementasi ISO 9000 seringkali dikaitkan dengan Total Quality Management (TQM). Ban...

Functionalized bimodal mesoporous silicas as carriers for controlled aspirin delivery

International Nuclear Information System (INIS)

Gao Lin; Sun Jihong; Li Yuzhen

2011-01-01

The bimodal mesoporous silica modified with 3-aminopropyltriethoxysilane was performed as the aspirin carrier. The samples' structure, drug loading and release profiles were characterized with X-ray diffraction, scanning electron microscopy, N 2 adsorption and desorption, Fourier transform infrared spectroscopy, TG analysis, elemental analysis and UV-spectrophotometer. For further exploring the effects of the bimodal mesopores on the drug delivery behavior, the unimodal mesoporous material MCM-41 was also modified as the aspirin carrier. Meantime, Korsmeyer-Peppas equation f t =kt n was employed to analyze the dissolution data in details. It is indicated that the bimodal mesopores are beneficial for unrestricted drug molecules diffusing and therefore lead to a higher loading and faster releasing than that of MCM-41. The results show that the aspirin delivery properties are influenced considerably by the mesoporous matrix, whereas the large pore of bimodal mesoporous silica is the key point for the improved controlled-release properties. - Graphical abstract: Loading (A) and release profiles (B) of aspirin in N-BMMs and N-MCM-41 indicated that BMMs have more drug loading capacity and faster release rate than that MCM-41. Highlights: → Bimodal mesoporous silicas (BMMs) and MCM-41 modified with amino group via post-treatment procedure. → Loading and release profiles of aspirin in modified BMMs and MCM-41. → Modified BMMs have more drug loading capacity and faster release rate than that modified MCM-41.

Multiple regimes of operation in bimodal AFM: understanding the energy of cantilever eigenmodes

Directory of Open Access Journals (Sweden)

Daniel Kiracofe

2013-06-01

Full Text Available One of the key goals in atomic force microscopy (AFM imaging is to enhance material property contrast with high resolution. Bimodal AFM, where two eigenmodes are simultaneously excited, confers significant advantages over conventional single-frequency tapping mode AFM due to its ability to provide contrast between regions with different material properties under gentle imaging conditions. Bimodal AFM traditionally uses the first two eigenmodes of the AFM cantilever. In this work, the authors explore the use of higher eigenmodes in bimodal AFM (e.g., exciting the first and fourth eigenmodes. It is found that such operation leads to interesting contrast reversals compared to traditional bimodal AFM. A series of experiments and numerical simulations shows that the primary cause of the contrast reversals is not the choice of eigenmode itself (e.g., second versus fourth, but rather the relative kinetic energy between the higher eigenmode and the first eigenmode. This leads to the identification of three distinct imaging regimes in bimodal AFM. This result, which is applicable even to traditional bimodal AFM, should allow researchers to choose cantilever and operating parameters in a more rational manner in order to optimize resolution and contrast during nanoscale imaging of materials.

The stability of iso-α-acids and reduced iso-α-acids in stored blood specimens.

Science.gov (United States)

Rodda, Luke N; Gerostamoulos, Dimitri; Drummer, Olaf H

2014-06-01

The long-term stability of the iso-α-acids, and three structurally similar but chemically altered iso-α-acids (known as 'reduced iso-α-acids' and consisting of the rho-, tetrahydro- and hexahydro-iso-α-acid groups) were investigated in whole blood. Pools of blank blood spiked with the four beer-specific ingredient congener groups at two different concentration levels were stored at 20°C, 4°C and -20°C; and extracted in duplicate in weeks 1, 3, 5 and 8, using a previously published method. A loss of 15% of the initial concentration was considered to indicate possible instability and losses greater than 30% demonstrated significant losses. The individual analytes within the four iso-α-acid groups were also measured to determine which iso-α-acids were subject to greater degradation and were responsible for the overall group instability. All four iso-α-acid groups showed significant losses after 8 weeks of storage under room temperature conditions in particularly the natural iso-α-acid group where major losses were observed (96% and 85% losses for low and high concentrations, respectively). Some degradation in all iso-α-acid groups were seen at 4°C samples predominantly due to the 'n' analogs of the groups showing an increased instability in blood. The -20°C storage conditions resulted in minimal changes in concentrations of all analytes. Higher than frozen storage temperatures can result in substantial changes on the stability of the iso-α-acid type groups in blood. The aim of this study was to highlight the stabilities of the IAA analytes in order to assist in the interpretation of IAA in stored blood specimens. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Bimodal distribution of glucose is not universally useful for diagnosing diabetes

DEFF Research Database (Denmark)

Vistisen, Dorte; Colagiuri, Stephen; Borch-Johnsen, Knut

2009-01-01

OBJECTIVE: Bimodality in the distribution of glucose has been used to define the cut point for the diagnosis of diabetes. Previous studies on bimodality have primarily been in populations with a high prevalence of type 2 diabetes, including one study in a white Caucasian population. All studies i...

Sensorless adaptive optics for isoSTED nanoscopy

Science.gov (United States)

Antonello, Jacopo; Hao, Xiang; Allgeyer, Edward S.; Bewersdorf, Joerg; Rittscher, Jens; Booth, Martin J.

2018-02-01

The presence of aberrations is a major concern when using fluorescence microscopy to image deep inside tissue. Aberrations due to refractive index mismatch and heterogeneity of the specimen under investigation cause severe reduction in the amount of fluorescence emission that is collected by the microscope. Furthermore, aberrations adversely affect the resolution, leading to loss of fine detail in the acquired images. These phenomena are particularly troublesome for super-resolution microscopy techniques such as isotropic stimulated-emission-depletion microscopy (isoSTED), which relies on accurate control of the shape and co-alignment of multiple excitation and depletion foci to operate as expected and to achieve the super-resolution effect. Aberrations can be suppressed by implementing sensorless adaptive optics techniques, whereby aberration correction is achieved by maximising a certain image quality metric. In confocal microscopy for example, one can employ the total image brightness as an image quality metric. Aberration correction is subsequently achieved by iteratively changing the settings of a wavefront corrector device until the metric is maximised. This simplistic approach has limited applicability to isoSTED microscopy where, due to the complex interplay between the excitation and depletion foci, maximising the total image brightness can lead to introducing aberrations in the depletion foci. In this work we first consider the effects that different aberration modes have on isoSTED microscopes. We then propose an iterative, wavelet-based aberration correction algorithm and evaluate its benefits.

ISO 14000 : environmental management systems

International Nuclear Information System (INIS)

Boutin, C.; Emard, C.; Lalonde, G.; Levesque, A.; Robitaille, R.; Rollin, A.L.; Thibeault, I.

1996-01-01

This book is addressed to the managers, professionals, and government agents which wish to know the philosophy of the step as well as the stages to be followed for the establishment of a system of environmental management in conformity with the standards of the series ISO 14000. This work locates ISO 14000 in the historical context of its development by describing the bonds with other standards in place of which those of the series ISO 9000. This book answers questions that arise regarding a companies step toward accreditation to ISO 14000

NDT technical assessment for ISO 17025 and ISO 17020 certification

International Nuclear Information System (INIS)

Mohamad Pauzi Ismail

2011-01-01

ISO 17025 is an international standard that states the requirement criteria for testing and calibration laboratory, while ISO 17020 is for inspection body. Standard Malaysia is the accreditation body for both standards. The author involved in the technical assessment for both standards both in Nuclear Malaysia and outside. The experience in performing NDT assessment activity is explained and discussed. The comparison between both standards is also discussed. (author)

Explanation and practice on ISO 9000

International Nuclear Information System (INIS)

Kwon, Dong Myeong

2001-01-01

This book reveals introduction on revision of ISO 9000:2000 with full account and contents of revision and change method change into ISO 9001:2000, the basic principle on ISO 9000:2000 and improvement and aim, definition on explanation, method for detail term, demand for ISO/KS A 9001:2000, quality management system development and transition way, standardization for quality management, manual of quality and making procedure and guide, case of quality manual and procedure and guide and ISO 9001:2000 / KS A 9001:2001 an English-Korean translation.

An effective inversion algorithm for retrieving bimodal aerosol particle size distribution from spectral extinction data

International Nuclear Information System (INIS)

He, Zhenzong; Qi, Hong; Yao, Yuchen; Ruan, Liming

2014-01-01

The Ant Colony Optimization algorithm based on the probability density function (PDF-ACO) is applied to estimate the bimodal aerosol particle size distribution (PSD). The direct problem is solved by the modified Anomalous Diffraction Approximation (ADA, as an approximation for optically large and soft spheres, i.e., χ⪢1 and |m−1|⪡1) and the Beer–Lambert law. First, a popular bimodal aerosol PSD and three other bimodal PSDs are retrieved in the dependent model by the multi-wavelength extinction technique. All the results reveal that the PDF-ACO algorithm can be used as an effective technique to investigate the bimodal PSD. Then, the Johnson's S B (J-S B ) function and the modified beta (M-β) function are employed as the general distribution function to retrieve the bimodal PSDs under the independent model. Finally, the J-S B and M-β functions are applied to recover actual measurement aerosol PSDs over Beijing and Shanghai obtained from the aerosol robotic network (AERONET). The numerical simulation and experimental results demonstrate that these two general functions, especially the J-S B function, can be used as a versatile distribution function to retrieve the bimodal aerosol PSD when no priori information about the PSD is available. - Highlights: • Bimodal PSDs are retrieved by ACO based on probability density function accurately. • J-S B and M-β functions can be used as the versatile function to recover bimodal PSDs. • Bimodal aerosol PSDs can be estimated by J-S B function more reasonably

Laadun- ja riskienhallinta johtamisjärjestelmässä ISO 9001:2015 ja ISO 31000:2009 mukaisesti

OpenAIRE

Reinvall, Niko; Karhunen, Joonas

2015-01-01

Tämän opinnäytetyön tarkoituksena on tarkastella riskienhallinnan ja laadunhallintajärjestelmien suhdetta ISO 9001:2015 ja ISO 31000:2009-standardien viitekehyksessä, tutkimuskysymyksen ollessa ”miten ja miksi integroida ISO 9001 mukaista laadunhallintaa ja ISO 31000 mukaista riskienhallintaa organisaation johtamisjärjestelmään”. Lisäksi työssä tarkastellaan standardien välisiä yhtymäkohtia ja riskienhallinnan merkitystä ISO 9001:2015 mukaisessa laadunhallintajärjestelmässä. Työn tilaaja...

75 FR 7581 - RTO/ISO Performance Metrics; Notice Requesting Comments on RTO/ISO Performance Metrics

Science.gov (United States)

2010-02-22

... performance communicate about the benefits of RTOs and, where appropriate, (2) changes that need to be made to... of staff from all the jurisdictional ISOs/RTOs to develop a set of performance metrics that the ISOs/RTOs will use to report annually to the Commission. Commission staff and representatives from the ISOs...

Corredor Bimodal Cafetero

OpenAIRE

Duque Escobar, Gonzalo

2015-01-01

El Corredor Bimodal Cafetero es un proyecto de infraestructura estratégica que articula la Hidrovía del Magdalena con el Corredor Férreo del río Cauca, inscrito en el Plan Nacional de Desarrollo 2014/2018 y financiable con la salida de 30 mil toneladas diarias de carbón andino a la cuenca del Pacífico. Incluye el Túnel Cumanday para cruzar la Cordillera Central, el Ferrocarril Cafetero de 150 km y 3% de pendiente entre La Dorada y el Km 41, y la Transversal Cafetera de 108 km para una vía de...

A course in bimodal provability logic

NARCIS (Netherlands)

Visser, A.

The aim of the present paper is twofold: first I am somewhat dissatisfied with current treatments of Bimodal Provability Logic: the models employed there are singled out by certain syntactical conditions, moreover they validate the logics under consideration only locally. In this paper I give a

The development and validation of an ergonomics index for assessing tractor operator work place

OpenAIRE

Barbieri, Juan Paulo; Schlosser, José Fernando; Farias, Marcelo Silveira de; Negri, Giácomo Müller; Oliveira, Luis Fernando Vargas de

2018-01-01

ABSTRACT: This study aimed to develop and validate an ergonomics index for the operator workplace assessment of agricultural tractors sold in the Brazilian market. To develop the ergonomics index, the operator work places were assessed for compliance with current, national and international, safety and ergonomics standards. The following standards were analyzed to develop ergonomics index: ISO 15077 (1996), which regulates the position of operator controls; ABNT NBR ISO 4254-1(2015) and ABNT ...

Partial replacement of fish meal by T-Iso in gilthead sea bream (Sparus aurata juveniles diets

Directory of Open Access Journals (Sweden)

Ivo Zoccarato

2010-01-01

Full Text Available The aim of this study was the evaluation of microalga Isochrysis sp. T-Iso in partial substitution of fish meal and the study of the effects on gilthead sea bream (Sparus aurata perform- ances and chemical composition of fillets. The results show that the microalga T-Iso nutrients support growth better than control diets, and the chemical composition of sea bream fillets also meets the needs of consumers for healthy diets. T-Iso resulted highly digestible, and support the best perform- ances of fish fed on 70% alga diet probably due to its high protein efficiency in comparison to other diets. The presence of a high quantity of cyclic isoprenoid could explain this high efficiency of T-Iso. Gilthead sea bream fed on 70% T-Iso showed fillets with a low level of protein and a high level of fat; moreover, their somatic indexes were higher than those of fish fed other diets. Highest percentage T- Iso diet showed the highest amount of the sum of saturated fatty acids, mainly due to myristate and palmitate. On the contrary, the sum of polyunsaturated decreases, mainly because of the reduction of EPA and DHA amounts. If the mass production economical problems are solved, T-Iso will represent a good solution in partial substitution of fish meal.

ISO 639-1 and ISO 639-2: International Standards for Language Codes. ISO 15924: International Standard for Names of Scripts.

Science.gov (United States)

Byrum, John D.

This paper describes two international standards for the representation of the names of languages. The first (ISO 639-1), published in 1988, provides two-letter codes for 136 languages and was produced primarily to meet terminological needs. The second (ISO 639-2) appeared in late 1998 and includes three-letter codes for 460 languages. This list…

Bimodal atomic force microscopy imaging of isolated antibodies in air and liquids

International Nuclear Information System (INIS)

MartInez, N F; Lozano, J R; Herruzo, E T; Garcia, F; Garcia, R; Richter, C; Sulzbach, T

2008-01-01

We have developed a dynamic atomic force microscopy (AFM) method based on the simultaneous excitation of the first two flexural modes of the cantilever. The instrument, called a bimodal atomic force microscope, allows us to resolve the structural components of antibodies in both monomer and pentameric forms. The instrument operates in both high and low quality factor environments, i.e., air and liquids. We show that under the same experimental conditions, bimodal AFM is more sensitive to compositional changes than amplitude modulation AFM. By using theoretical and numerical methods, we study the material contrast sensitivity as well as the forces applied on the sample during bimodal AFM operation

The development and validation of an ergonomics index for assessing tractor operator work place

Directory of Open Access Journals (Sweden)

Juan Paulo Barbieri

2018-02-01

Full Text Available ABSTRACT: This study aimed to develop and validate an ergonomics index for the operator workplace assessment of agricultural tractors sold in the Brazilian market. To develop the ergonomics index, the operator work places were assessed for compliance with current, national and international, safety and ergonomics standards. The following standards were analyzed to develop ergonomics index: ISO 15077 (1996, which regulates the position of operator controls; ABNT NBR ISO 4254-1(2015 and ABNT NBR ISO 4252 (2011, which regulate the access to operator workplaces; and NR 12 (2010, which determines the mandatory items of operator workplaces.Thirty-four operator work places of 152 models of new agricultural tractors sold in the Brazilian market were analyzed in this study. Ergonomics index was developed and validated using these standards, and the findings enabled the ranking of agricultural tractors. Therefore, the proposed ergonomics index proved feasible and may be applied to other agricultural machines.

Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.

Science.gov (United States)

Moberly, Aaron C; Lowenstein, Joanna H; Nittrouer, Susan

2016-01-01

Adding a low-frequency acoustic signal to the cochlear implant (CI) signal (i.e., bimodal stimulation) for a period of time early in life improves language acquisition. Children must acquire sensitivity to the phonemic units of language to develop most language-related skills, including expressive vocabulary, working memory, and reading. Acquiring sensitivity to phonemic structure depends largely on having refined spectral (frequency) representations available in the signal, which does not happen with CIs alone. Combining the low-frequency acoustic signal available through hearing aids with the CI signal can enhance signal quality. A period with this bimodal stimulation has been shown to improve language skills in very young children. This study examined whether these benefits persist into childhood. Data were examined for 48 children with CIs implanted under age 3 years, participating in a longitudinal study. All children wore hearing aids before receiving a CI, but upon receiving a first CI, 24 children had at least 1 year of bimodal stimulation (Bimodal group), and 24 children had only electric stimulation subsequent to implantation (CI-only group). Measures of phonemic awareness were obtained at second and fourth grades, along with measures of expressive vocabulary, working memory, and reading. Children in the Bimodal group generally performed better on measures of phonemic awareness, and that advantage was reflected in other language measures. Having even a brief period of time early in life with combined electric-acoustic input provides benefits to language learning into childhood, likely because of the enhancement in spectral representations provided.

Bimodal emotion congruency is critical to preverbal infants' abstract rule learning.

Science.gov (United States)

Tsui, Angeline Sin Mei; Ma, Yuen Ki; Ho, Anna; Chow, Hiu Mei; Tseng, Chia-huei

2016-05-01

Extracting general rules from specific examples is important, as we must face the same challenge displayed in various formats. Previous studies have found that bimodal presentation of grammar-like rules (e.g. ABA) enhanced 5-month-olds' capacity to acquire a rule that infants failed to learn when the rule was presented with visual presentation of the shapes alone (circle-triangle-circle) or auditory presentation of the syllables (la-ba-la) alone. However, the mechanisms and constraints for this bimodal learning facilitation are still unknown. In this study, we used audio-visual relation congruency between bimodal stimulation to disentangle possible facilitation sources. We exposed 8- to 10-month-old infants to an AAB sequence consisting of visual faces with affective expressions and/or auditory voices conveying emotions. Our results showed that infants were able to distinguish the learned AAB rule from other novel rules under bimodal stimulation when the affects in audio and visual stimuli were congruently paired (Experiments 1A and 2A). Infants failed to acquire the same rule when audio-visual stimuli were incongruently matched (Experiment 2B) and when only the visual (Experiment 1B) or the audio (Experiment 1C) stimuli were presented. Our results highlight that bimodal facilitation in infant rule learning is not only dependent on better statistical probability and redundant sensory information, but also the relational congruency of audio-visual information. A video abstract of this article can be viewed at https://m.youtube.com/watch?v=KYTyjH1k9RQ. © 2015 John Wiley & Sons Ltd.

Dynamical and statistical bimodality in nuclear fragmentation

Science.gov (United States)

Mallik, S.; Chaudhuri, G.; Gulminelli, F.

2018-02-01

The origin of bimodal behavior in the residue distribution experimentally measured in heavy ion reactions is reexamined using Boltzmann-Uehling-Uhlenbeck simulations. We suggest that, depending on the incident energy and impact parameter of the reaction, both entrance channel and exit channel effects can be at the origin of the observed behavior. Specifically, fluctuations in the reaction mechanism induced by fluctuations in the collision rate, as well as thermal bimodality directly linked to the nuclear liquid-gas phase transition, are observed in our simulations. Both phenomenologies were previously proposed in the literature but presented as incompatible and contradictory interpretations of the experimental measurements. These results indicate that heavy ion collisions at intermediate energies can be viewed as a powerful tool to study both bifurcations induced by out-of-equilibrium critical phenomena, as well as finite-size precursors of thermal phase transitions.

Control: the effects of ISO

NARCIS (Netherlands)

Laura Ilzarbe; PhD Everard van Kemenade; Maria-Jezus Alvarez

2007-01-01

De effecten van ISO-certificering zoals gerapporteerd in wetenschappelijk onderzoek. Met speciale aandacht voor de resultaten in het onderwijs. ISO 9000:2000 doet het nadrukkelijk beter dan haar vorige versies.

Deaf Children's Bimodal Bilingualism and Education

Science.gov (United States)

Swanwick, Ruth

2016-01-01

This paper provides an overview of the research into deaf children's bilingualism and bilingual education through a synthesis of studies published over the last 15 years. This review brings together the linguistic and pedagogical work on bimodal bilingualism to inform educational practice. The first section of the review provides a synthesis of…

International Organization for Standardization (ISO) 15189.

Science.gov (United States)

Schneider, Frank; Maurer, Caroline; Friedberg, Richard C

2017-09-01

The College of American Pathologists (CAP) offers a suite of laboratory accreditation programs, including one specific to accreditation to the international organization for standardization (ISO) 15189 standard for quality management specific to medical laboratories. CAP leaders offer an overview of ISO 15189 including its components, internal audits, occurrence management, document control, and risk management. The authors provide a comparison of its own ISO 15189 program, CAP 15189, to the CAP Laboratory Accreditation Program. The authors conclude with why laboratories should use ISO 15189. © The Korean Society for Laboratory Medicine.

A practical synthesis of long-chain iso-fatty acids (iso-C12–C19 and related natural products

Directory of Open Access Journals (Sweden)

Mark B. Richardson

2013-09-01

Full Text Available A gram-scale synthesis of terminally-branched iso-fatty acids (iso-C12–C19 was developed commencing with methyl undec-10-enoate (methyl undecylenate (for iso-C12–C14 or the C15 and C16 lactones pentadecanolide (for iso-C15–C17 and hexadecanolide (for iso-C18–C19. Central to the approaches outlined is the two-step construction of the terminal isopropyl group through addition of methylmagnesium bromide to the ester/lactones and selective reduction of the resulting tertiary alcohols. Thus, the C12, C17 and C18 iso-fatty acids were obtained in three steps from commercially-available starting materials, and the remaining C13–C16 and C19 iso-fatty acids were prepared by homologation or recursive dehomologations of these fatty acids or through intercepting appropriate intermediates. Highlighting the synthetic potential of the iso-fatty acids and various intermediates prepared herein, we describe the synthesis of the natural products (S-2,15-dimethylpalmitic acid, (S-2-hydroxy-15-methylpalmitic acid, and 2-oxo-14-methylpentadecane.

ISO 9000 Quality Management System

Science.gov (United States)

Hadjicostas, Evsevios

The ISO 9000 series describes a quality management system applicable to any organization. In this chapter we present the requirements of the standard in a way that is as close as possible to the needs of analytical laboratories. The sequence of the requirements follows that in the ISO 9001:2008 standard. In addition, the guidelines for performance improvement set out in the ISO 9004 are reviewed. Both standards should be used as a reference as well as the basis for further elaboration.

Bimodal Formation Time Distribution for Infall Dark Matter Halos

Science.gov (United States)

Shi, Jingjing; Wang, Huiyuan; Mo, H. J.; Xie, Lizhi; Wang, Xiaoyu; Lapi, Andrea; Sheth, Ravi K.

2018-04-01

We use a 200 {h}-1 {Mpc} a-side N-body simulation to study the mass accretion history (MAH) of dark matter halos to be accreted by larger halos, which we call infall halos. We define a quantity {a}nf}\\equiv (1+{z}{{f}})/(1+{z}peak}) to characterize the MAH of infall halos, where {z}peak} and {z}{{f}} are the accretion and formation redshifts, respectively. We find that, at given {z}peak}, their MAH is bimodal. Infall halos are dominated by a young population at high redshift and by an old population at low redshift. For the young population, the {a}nf} distribution is narrow and peaks at about 1.2, independent of {z}peak}, while for the old population, the peak position and width of the {a}nf} distribution both increase with decreasing {z}peak} and are both larger than those of the young population. This bimodal distribution is found to be closely connected to the two phases in the MAHs of halos. While members of the young population are still in the fast accretion phase at z peak, those of the old population have already entered the slow accretion phase at {z}peak}. This bimodal distribution is not found for the whole halo population, nor is it seen in halo merger trees generated with the extended Press–Schechter formalism. The infall halo population at {z}peak} are, on average, younger than the whole halo population of similar masses identified at the same redshift. We discuss the implications of our findings in connection to the bimodal color distribution of observed galaxies and to the link between central and satellite galaxies.

The European Large Area ISO Survey

DEFF Research Database (Denmark)

Oliver, S.; Rowan-Robinson, M.; Alexander, D.M.

2000-01-01

We describe the European Large Area ISO Survey (ELAIS). ELAIS was the largest single Open Time project conducted by ISO, mapping an area of 12 deg(2) at 15 mu m with ISOCAM and at 90 mu m with ISOPHOT. Secondary surveys in other ISO bands were undertaken by the ELAIS team within the fields of the...

How the bimodal format of presentation affects working memory: an overview.

Science.gov (United States)

Mastroberardino, Serena; Santangelo, Valerio; Botta, Fabiano; Marucci, Francesco S; Olivetti Belardinelli, Marta

2008-03-01

The best format in which information that has to be recalled is presented has been investigated in several studies, which focused on the impact of bimodal stimulation on working memory performance. An enhancement of participant's performance in terms of correct recall has been repeatedly found, when bimodal formats of presentation (i.e., audiovisual) were compared to unimodal formats (i.e, either visual or auditory), in providing implications for multimedial learning. Several theoretical frameworks have been suggested in order to account for the bimodal advantage, ranging from those emphasizing early stages of processing (such as automatic alerting effects or multisensory integration processes) to those centred on late stages of processing (as postulated by the dual coding theory). The aim of this paper is to review previous contributions to this topic, providing a comprehensive theoretical framework, which is updated by the latest empirical studies.

Evidence for a bimodal distribution in human communication.

Science.gov (United States)

Wu, Ye; Zhou, Changsong; Xiao, Jinghua; Kurths, Jürgen; Schellnhuber, Hans Joachim

2010-11-02

Interacting human activities underlie the patterns of many social, technological, and economic phenomena. Here we present clear empirical evidence from Short Message correspondence that observed human actions are the result of the interplay of three basic ingredients: Poisson initiation of tasks and decision making for task execution in individual humans as well as interaction among individuals. This interplay leads to new types of interevent time distribution, neither completely Poisson nor power-law, but a bimodal combination of them. We show that the events can be separated into independent bursts which are generated by frequent mutual interactions in short times following random initiations of communications in longer times by the individuals. We introduce a minimal model of two interacting priority queues incorporating the three basic ingredients which fits well the distributions using the parameters extracted from the empirical data. The model can also embrace a range of realistic social interacting systems such as e-mail and letter communications when taking the time scale of processing into account. Our findings provide insight into various human activities both at the individual and network level. Our analysis and modeling of bimodal activity in human communication from the viewpoint of the interplay between processes of different time scales is likely to shed light on bimodal phenomena in other complex systems, such as interevent times in earthquakes, rainfall, forest fire, and economic systems, etc.

Analysis of the Environmental Management System based on ISO 14001 on the American continent.

Science.gov (United States)

Neves, Fábio de Oliveira; Salgado, Eduardo G; Beijo, Luiz A

2017-09-01

The American continent is in broad economic and industrial development. Consequently, a more detailed discussion of the impacts generated by such development is needed. Moreover, there is an increase in the number of ISO 14001 certificates issued to this continent. Given the above, no studies were found that bridge the gap to identify the influence of different factors on ISO 14001 in the Americas. Thus, this article has as its main aim to check which economic, environmental and cultural factors have influence on ISO 14001 Certification in the American Continent. The data were collected in the ISO Survey, World Bank, United Nations Development Programme and International Energy Agency. Among the countries of that continent, thirteen were analyzed and only two did not show the economic factors as the influence factor in the multiple regression models fitted with Brazil and the United State. In these models, all presented environmental factors as influencing factors. Only in Brazil the index HDI presented as cultural factor in multiple regression model fitted. The economic factors: Gross Domestic Product and exports of goods and services and environmental: Carbon Dioxide (CO 2 ) and fossil fuel consumption were the most influential in ISO 14001 certification. Venezuela, Uruguay, Colombia and the United States were countries that had factors dependent on each other, featuring the environmental marketing. Briefly, this study brings up several implications: to the academy, with the proposal of new concepts and guidance on the factors that assist in ISO 14001 certification in the American Continent. Additionally, taking into account the industry, the factors serve as efficiency parameters for the implementation of ISO 14001 standard, and for the Government to improve through factors that do not fit in multiple regression models. Copyright © 2017 Elsevier Ltd. All rights reserved.

An effective inversion algorithm for retrieving bimodal aerosol particle size distribution from spectral extinction data

Science.gov (United States)

He, Zhenzong; Qi, Hong; Yao, Yuchen; Ruan, Liming

2014-12-01

The Ant Colony Optimization algorithm based on the probability density function (PDF-ACO) is applied to estimate the bimodal aerosol particle size distribution (PSD). The direct problem is solved by the modified Anomalous Diffraction Approximation (ADA, as an approximation for optically large and soft spheres, i.e., χ⪢1 and |m-1|⪡1) and the Beer-Lambert law. First, a popular bimodal aerosol PSD and three other bimodal PSDs are retrieved in the dependent model by the multi-wavelength extinction technique. All the results reveal that the PDF-ACO algorithm can be used as an effective technique to investigate the bimodal PSD. Then, the Johnson's SB (J-SB) function and the modified beta (M-β) function are employed as the general distribution function to retrieve the bimodal PSDs under the independent model. Finally, the J-SB and M-β functions are applied to recover actual measurement aerosol PSDs over Beijing and Shanghai obtained from the aerosol robotic network (AERONET). The numerical simulation and experimental results demonstrate that these two general functions, especially the J-SB function, can be used as a versatile distribution function to retrieve the bimodal aerosol PSD when no priori information about the PSD is available.

Mednarodni standardi - veličine in enote (ISO 31-0 do 31-13): International standards - quantities and units (ISO 31-0 to 31-13):

OpenAIRE

Glavič, Peter

2002-01-01

In this paper the international standards ISO 31 (Quantities and units) are presented with the following parts: ISO 31-0 (General principles), ISO 31-1 (Space and time), ISO 31-2 (Periodic and related phenomena), ISO 31-3 (Mechanics), ISO 31-4 (Heat), ISO 31-5 (Electricity and magnetism), ISO 31-8 (Physical chemistry and molecular physics), ISO 31-12 (Characteristic numbers)and others. The emphasis is given on the basic principles, which is important for writing of reports, presentations, art...

ISO27001 in a Windows Environment

CERN Document Server

Honan, Brian

2010-01-01

Ideal for project managers, IT and security staff, this book plugs the gap in current guidance literature for ISO27001. ISO27001, the information security management standard (ISMS), is providing a significant challenge for many organisations. One of the key areas of confusion is the relationship between the ISO27001 ISMS project manager and those responsible for implementing the technical controls.

Certification of ISO 9001: SSDL experiences

International Nuclear Information System (INIS)

Noriah Mod Ali

2005-01-01

Efforts given to maintain the quality management based on the ISO 9000 requirement able to improved the existing system, strengthen the customer confidence and to satisfied the worker needs. It gives direct impact on the harmonization of the Radiation Protection Program in the country. SSDL experiences towards obtaining the the ISO 9002/ISO 9001 certification and its maintenance are discussed in details. (Author)

From ISO 9001:2008 to ISO 9001:2015: Significant changes and their impacts to aspiring organizations

Science.gov (United States)

Sari, Y.; Wibisono, E.; Wahyudi, R. D.; Lio, Y.

2017-11-01

ISO 9001:2015 is the latest version of ISO Quality Management System standard that has been updated recently from ISO 9001:2008. It is necessary for all organizations that have implemented and been certified with ISO 9001:2008 to prepare the transition and upgrade their Quality Management System because the certification will expire by September 2018. This paper attempts to provide knowledge on the significant changes from ISO 9001:2008 to ISO 9001:2015, what new requirements are added, and how they would impact the organizations. An exploratory and applied research was chosen as the research approach and aimed to explore what transition designs are needed to anticipate the changes as well as their impacts. The research applied a methodology of Plan-Do-Check-Action (PDCA) cycle into four organizations and their results were compared and discussed to explain the transition designs. Some qualitative methods such as observation and interview were used to collect the data. By addressing the new requirements, three transition designs that should be prepared are: (i) identifying needs from interested parties, (ii) analyzing internal and external factors of the organizations to formulate relevant strategies and quality objectives, and (iii) registering risks associated to business processes as well as organizational strategies.

Definition of a CDI metadata profile and its ISO 19139 based encoding

Science.gov (United States)

Boldrini, Enrico; de Korte, Arjen; Santoro, Mattia; Schaap, Dick M. A.; Nativi, Stefano; Manzella, Giuseppe

2010-05-01

The Common Data Index (CDI) is the middleware service adopted by SeaDataNet for discovery and query. The primary goal of the EU funded project SeaDataNet is to develop a system which provides transparent access to marine data sets and data products from 36 countries in and around Europe. The European context of SeaDataNet requires that the developed system complies with European Directive INSPIRE. In order to assure the required conformity a GI-cat based solution is proposed. GI-cat is a broker service able to mediate from different metadata sources and publish them through a consistent and unified interface. In this case GI-cat is used as a front end to the SeaDataNet portal publishing the original data, based on CDI v.1 XML schema, through an ISO 19139 application profile catalog interface (OGC CSW AP ISO). The choice of ISO 19139 is supported and driven by INSPIRE Implementing Rules, that have been used as a reference through the whole development process. A mapping from the CDI data model to the ISO 19139 was hence to be implemented in GI-cat and a first draft quickly developed, as both CDI v.1 and ISO 19139 happen to be XML implementations based on the same abstract data model (standard ISO 19115 - metadata about geographic information). This first draft mapping pointed out the CDI metadata model differences with respect to ISO 19115, as it was not possible to accommodate all the information contained in CDI v.1 into ISO 19139. Moreover some modifications were needed in order to reach INSPIRE compliance. The consequent work consisted in the definition of the CDI metadata model as a profile of ISO 19115. This included checking of all the metadata elements present in CDI and their cardinality. A comparison was made with respect to ISO 19115 and possible extensions were individuated. ISO 19139 was then chosen as a natural XML implementation of this new CDI metadata profile. The mapping and the profile definition processes were iteratively refined leading up to a

ISO specifications and unclear energy quality certification

Energy Technology Data Exchange (ETDEWEB)

Lee, Tae Hun

2011-12-15

This book indicates necessity of quality management and change of company environment, basic conception of quality management and thinking way, role of each class for quality management, necessity and purpose of introduction of ISO9000 family, authentication process and construct method of ISO9000 family, authentication effect of ISO9000 family, present condition of ISO9000 family, standard of quality certification and quality management and explanation of 2001 requirement of KSA9000.

ISO specifications and unclear energy quality certification

International Nuclear Information System (INIS)

Lee, Tae Hun

2011-12-01

This book indicates necessity of quality management and change of company environment, basic conception of quality management and thinking way, role of each class for quality management, necessity and purpose of introduction of ISO9000 family, authentication process and construct method of ISO9000 family, authentication effect of ISO9000 family, present condition of ISO9000 family, standard of quality certification and quality management and explanation of 2001 requirement of KSA9000.

Adopting ISO 9712:2005 and ISO/IEC 17024:2003 as Philippine national standard for NDT for global competitiveness

International Nuclear Information System (INIS)

Banaga, Renato T.; Mateo, Alejandro J.

2005-01-01

This paper describes and promotes the adoption of ISO 9712: 2005 edition and the ISO/IEC 17024: 2003 edition by the Philippines to be globally competitive. ISO 9712 is a standard for qualifications and certification of nondestructive testing (NDT) personnel while ISO/IEC 17024 is conformity assessment-general requirements for bodies operating certification of persons. ISO 9712 defies that the effectiveness of an application of nondestructive testing depends on the capabilities and qualifications of personnel performing the NDT test. The Philippines through the national certifying body (NCB) implements the certification of proficiency of NDT personnel in accordance with the Philippine National Standards (PNS-146: 1998) This standard (formerly PNS-146: 1987) was originally based from the draft ISO/TC-135/SC7N35.3 and was later revised to conform to the latest ISO FDIS 9712: 1997 and rename PNS-146: 1998. Now with the issuance of the latest ISO 9712:2005 edition and to keep abreast with the current trends of NDT technology, present time and conditions dictates for us to revise our NDT personnel certification to the latest edition of ISO 9712. The International Atomic Energy Agency (IAEA) supports the establishment of a common NDT standard. The IAEA is promoting af financially supporting the establishment in developing countries of only one NDT standard. The IAEA through the Regional Cooperative Agreement (RCA) has initiated the harmonization of the NDT qualification and certification of personnel in the RCA member states. In October 2001, the IAEA sponsored the Dhaka meeting where the International Committee for Nondestructive Testing (ICNDT), Asia-Pacific Committee (APCNDT) and RCA member states representatives drafted a Mutual Recognition Agreement (MRA) for the Asia-Pacific NDT (APCNDT) personnel certification schemes acording to ISO 9712. Last August 2005, IAEA/RCA sponsored the Colombo meeting for the harmonization of regional NDT applying ISO 9712 and ISO

Bimodal Reading: Benefits of a Talking Computer for Average and Less Skilled Readers.

Science.gov (United States)

Montali, Julie; Lewandowski, Lawrence

1996-01-01

Eighteen average readers and 18 less-skilled readers (grades 8 and 9) were presented with social studies and science passages via a computer either visually (on screen), auditorily (read by digitized voice), or bimodally (on screen, highlighted while being voiced). Less-skilled readers demonstrated comprehension in the bimodal condition equivalent…

Quantifying Young's moduli of protein fibrils and particles with bimodal force spectroscopy.

Science.gov (United States)

Gilbert, Jay; Charnley, Mirren; Cheng, Christopher; Reynolds, Nicholas P; Jones, Owen G

2017-10-19

Force spectroscopy is a means of obtaining mechanical information of individual nanometer-scale structures in composite materials, such as protein assemblies for use in consumer films or gels. As a recently developed force spectroscopy technique, bimodal force spectroscopy relates frequency shifts in cantilevers simultaneously excited at multiple frequencies to the elastic properties of the contacted material, yet its utility for quantitative characterization of biopolymer assemblies has been limited. In this study, a linear correlation between experimental frequency shift and Young's modulus of polymer films was used to calibrate bimodal force spectroscopy and quantify Young's modulus of two protein nanostructures: β-lactoglobulin fibrils and zein nanoparticles. Cross-sectional Young's modulus of protein fibrils was determined to be 1.6 GPa while the modulus of zein nanoparticles was determined as 854 MPa. Parallel measurement of β-lactoglobulin fibril by a competing pulsed-force technique found a higher cross-sectional Young's modulus, highlighting the importance of comparative calibration against known standards in both pulsed and bimodal force spectroscopies. These findings demonstrate a successful procedure for measuring mechanical properties of individual protein assemblies with potential use in biological or packaging applications using bimodal force spectroscopy.

Promoting Strong ISO 50001 Outcomes with Supportive National Infrastructure

Energy Technology Data Exchange (ETDEWEB)

McKane, Aimee, T.; Siciliano, Graziella; de los Reyes, Pamela

2015-08-04

The ISO 50001 standard is a key mechanism for reducing greenhouse gas emissions and improving energy efficiency globally. An increasing number of companies are seeking certification, creating the need for personnel that are competent to conduct ISO 50001 certification audits. The growth of ISO 50001 is expected to accelerate as more companies integrate ISO 50001 into their corporate sustainability strategies and supplier requirements. Robust implementation of ISO 50001 represents an important tool for countries with climate change mitigation goals. Because of its dual focus on continual improvement of an organization’s energy management system (EnMS) and its energy performance improvement, ISO 50001 requires skills of both implementers and certification auditors that are not well-supported by current credentials and training. This paper describes an effort to address skill gaps of certification auditors, a critical factor to ensure that ISO 50001 implementations are robust and result in continued energy performance improvement. A collaboration of governments through the Energy Management Working Group (EMWG), formerly under Global Superior Energy Performance (GSEP), has formed to build workforce capacity for ISO 50001 certification audits. The EMWG is leading the development of an internationally-relevant certification scheme for ISO 50001 Lead Auditor that meets requirements for ISO/IEC 17024 accreditation and ISO 50003 for defining ISO 50001 Lead Auditor competency. Wider availability of competent ISO 50001 Lead Auditors will ultimately increase the impact and market value of ISO 50001 certification and improve consistency of ISO 50001 certification outcomes by establishing a standardized and high level of knowledge and skills globally.

Improving Earth Science Metadata: Modernizing ncISO

Science.gov (United States)

O'Brien, K.; Schweitzer, R.; Neufeld, D.; Burger, E. F.; Signell, R. P.; Arms, S. C.; Wilcox, K.

2016-12-01

ncISO is a package of tools developed at NOAA's National Center for Environmental Information (NCEI) that facilitates the generation of ISO 19115-2 metadata from NetCDF data sources. The tool currently exists in two iterations: a command line utility and a web-accessible service within the THREDDS Data Server (TDS). Several projects, including NOAA's Unified Access Framework (UAF), depend upon ncISO to generate the ISO-compliant metadata from their data holdings and use the resulting information to populate discovery tools such as NCEI's ESRI Geoportal and NOAA's data.noaa.gov CKAN system. In addition to generating ISO 19115-2 metadata, the tool calculates a rubric score based on how well the dataset follows the Attribute Conventions for Dataset Discovery (ACDD). The result of this rubric calculation, along with information about what has been included and what is missing is displayed in an HTML document generated by the ncISO software package. Recently ncISO has fallen behind in terms of supporting updates to conventions such updates to the ACDD. With the blessing of the original programmer, NOAA's UAF has been working to modernize the ncISO software base. In addition to upgrading ncISO to utilize version1.3 of the ACDD, we have been working with partners at Unidata and IOOS to unify the tool's code base. In essence, we are merging the command line capabilities into the same software that will now be used by the TDS service, allowing easier updates when conventions such as ACDD are updated in the future. In this presentation, we will discuss the work the UAF project has done to support updated conventions within ncISO, as well as describe how the updated tool is helping to improve metadata throughout the earth and ocean sciences.

Unimodal Versus Bimodal EEG-fMRI Neurofeedback of a Motor Imagery Task

Directory of Open Access Journals (Sweden)

Lorraine Perronnet

2017-04-01

Full Text Available Neurofeedback is a promising tool for brain rehabilitation and peak performance training. Neurofeedback approaches usually rely on a single brain imaging modality such as EEG or fMRI. Combining these modalities for neurofeedback training could allow to provide richer information to the subject and could thus enable him/her to achieve faster and more specific self-regulation. Yet unimodal and multimodal neurofeedback have never been compared before. In the present work, we introduce a simultaneous EEG-fMRI experimental protocol in which participants performed a motor-imagery task in unimodal and bimodal NF conditions. With this protocol we were able to compare for the first time the effects of unimodal EEG-neurofeedback and fMRI-neurofeedback versus bimodal EEG-fMRI-neurofeedback by looking both at EEG and fMRI activations. We also propose a new feedback metaphor for bimodal EEG-fMRI-neurofeedback that integrates both EEG and fMRI signal in a single bi-dimensional feedback (a ball moving in 2D. Such a feedback is intended to relieve the cognitive load of the subject by presenting the bimodal neurofeedback task as a single regulation task instead of two. Additionally, this integrated feedback metaphor gives flexibility on defining a bimodal neurofeedback target. Participants were able to regulate activity in their motor regions in all NF conditions. Moreover, motor activations as revealed by offline fMRI analysis were stronger during EEG-fMRI-neurofeedback than during EEG-neurofeedback. This result suggests that EEG-fMRI-neurofeedback could be more specific or more engaging than EEG-neurofeedback. Our results also suggest that during EEG-fMRI-neurofeedback, participants tended to regulate more the modality that was harder to control. Taken together our results shed first light on the specific mechanisms of bimodal EEG-fMRI-neurofeedback and on its added-value as compared to unimodal EEG-neurofeedback and fMRI-neurofeedback.

Complexing properties of α-iso-saccharinate: thorium

International Nuclear Information System (INIS)

Allard, S.; Ekberg, C.

2005-01-01

Full text of publication follows: In the alkaline conditions of the intended Swedish repository for long-lived, low to intermediate level waste, SFL3-5, cellulose based items will degrade with iso-saccharinate being the dominant end-product. Iso-saccharinate is a strong complexing agent for tetravalent actinides, as well as for trivalent lanthanides, and its complexation properties are of interest for the long-term repository assessment. In the presented study, the complexation of 234 Th-α-iso-saccharinate is examined using liquid-liquid- extraction and radioanalytical techniques. An organic phase consisting of 0.1 M acetylacetone in toluene was used with a 1.0 M NaClO 4 aqueous phase kept at pH 8 in a thermostated AKUFVE unit. Since the α-iso-saccharinic system consists of three species - the carboxylic α-iso-saccharinic acid, α-iso-saccharinate and α-D-iso-saccharino-1,4-lactone - care must be taken when choosing the operational pH. Keeping the aqueous phase at pH 8 results in negligible concentrations of all but the α-iso-saccharinate form while at the same time being an excellent pH for the 234 Th-acetylacetone complexation with very limited hydrolysis effect. The α- iso-saccharinate concentration was incrementally increased, and samples of equal volumes were taken from the two phases and analyzed in a liquid scintillation detector once the radioactive equilibrium between 234 Th and 234 Pa had been reached. Two complexation constants were used to fit a distribution equation to the experimental data. (authors)

Bi-modal G\\"odel logic over [0,1]-valued Kripke frames

OpenAIRE

Caicedo, Xavier; Rodriguez, Ricardo Oscar

2011-01-01

We consider the G\\"odel bi-modal logic determined by fuzzy Kripke models where both the propositions and the accessibility relation are infinitely valued over the standard G\\"odel algebra [0,1] and prove strong completeness of Fischer Servi intuitionistic modal logic IK plus the prelinearity axiom with respect to this semantics. We axiomatize also the bi-modal analogues of $T,$ $S4,$ and $S5$ obtained by restricting to models over frames satisfying the [0,1]-valued versions of the structural ...

ISO standards on the evaluation of contamination

International Nuclear Information System (INIS)

Swinth, K.L.; Tamberg, T.A.

1993-01-01

The International Organization for Standardization (ISO) develops radiation calibration standards through Subcommittee 2 (titled ''Radiation Protection'') of Technical Committee 85 (ISO/TC85/SC2). The subcommittee has also developed standards providing guidance on the performance of measurements. ISO/TC85/SC2 consists of international technical experts who represent their countries through the international consensus process in providing guidance in several radiation protection areas. The purpose of this paper is to summarize ISO's is guidance provided in the area of contamination measurements

Bimodal SLD Ice Accretion on a NACA 0012 Airfoil Model

Science.gov (United States)

Potapczuk, Mark; Tsao, Jen-Ching; King-Steen, Laura

2016-01-01

This presentation describes the results of ice accretion measurements on a NACA 0012 airfoil model, from the NASA Icing Research Tunnel, using an icing cloud composed of a bimodal distribution of Supercooled Large Droplets. The data consists of photographs, laser scans of the ice surface, and measurements of the mass of ice for each icing condition. The results of ice shapes accumulated as a result of exposure to an icing cloud with a bimodal droplet distribution were compared to the ice shapes resulting from an equivalent cloud composed of a droplet distribution with a standard bell curve shape.

Microbubble embedded with upconversion nanoparticles as a bimodal contrast agent for fluorescence and ultrasound imaging

International Nuclear Information System (INIS)

Jin, Birui; Lin, Min; You, Minli; Xu, Feng; Lu, Tianjian; Zong, Yujin; Wan, Mingxi; Duan, Zhenfeng

2015-01-01

Bimodal imaging offers additional imaging signal thus finds wide spread application in clinical diagnostic imaging. Fluorescence/ultrasound bimodal imaging contrast agent using fluorescent dyes or quantum dots for fluorescence signal has emerged as a promising method, which however requires visible light or UV irradiation resulting in photobleaching, photoblinking, auto-fluorescence and limited tissue penetration depth. To surmount these problems, we developed a novel bimodal contrast agent using layer-by-layer assembly of upconversion nanoparticles onto the surface of microbubbles. The resulting microbubbles with average size of 2 μm provide enhanced ultrasound echo for ultrasound imaging and upconversion emission upon near infrared irradiation for fluorescence imaging. The developed bimodal contrast agent holds great potential to be applied in ultrasound target technique for targeted diseases diagnostics and therapy. (paper)

Usability evaluation of mobile applications using ISO 9241 and ISO 25062 standards.

Science.gov (United States)

Moumane, Karima; Idri, Ali; Abran, Alain

2016-01-01

This paper presents an empirical study based on a set of measures to evaluate the usability of mobile applications running on different mobile operating systems, including Android, iOS and Symbian. The aim is to evaluate empirically a framework that we have developed on the use of the Software Quality Standard ISO 9126 in mobile environments, especially the usability characteristic. To do that, 32 users had participated in the experiment and we have used ISO 25062 and ISO 9241 standards for objective measures by working with two widely used mobile applications: Google Apps and Google Maps. The QUIS 7.0 questionnaire have been used to collect measures assessing the users' level of satisfaction when using these two mobile applications. By analyzing the results we highlighted a set of mobile usability issues that are related to the hardware as well as to the software and that need to be taken into account by designers and developers in order to improve the usability of mobile applications.

Refining Bimodal Microstructure of Materials with MSTRUCT

Czech Academy of Sciences Publication Activity Database

Matěj, Z.; Kadlecová, A.; Janeček, M.; Matějová, Lenka; Dopita, M.; Kužel, R.

2014-01-01

Roč. 29, S2 (2014), S35-S41 ISSN 0885-7156 R&D Projects: GA ČR GA14-23274S Grant - others:UK(CZ) UNCE 204023/2012 Institutional support: RVO:67985858 Keywords : XRD * bimodal * crystallite size Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.636, year: 2014

[ISO 15189 medical laboratory accreditation].

Science.gov (United States)

Aoyagi, Tsutomu

2004-10-01

This International Standard, based upon ISO/IEC 17025 and ISO 9001, provides requirements for competence and quality that are particular to medical laboratories. While this International Standard is intended for use throughout the currently recognized disciplines of medical laboratory services, those working in other services and disciplines will also find it useful and appropriate. In addition, bodies engaged in the recognition of the competence of medical laboratories will be able to use this International Standard as the basis for their activities. The Japan Accreditation Board for Conformity Assessment (AB) and the Japanese Committee for Clinical Laboratory Standards (CCLS) are jointly developing the program of accreditation of medical laboratories. ISO 15189 requirements consist of two parts, one is management requirements and the other is technical requirements. The former includes the requirements of all parts of ISO 9001, moreover it includes the requirement of conformity assessment body, for example, impartiality and independence from any other party. The latter includes the requirements of laboratory competence (e.g. personnel, facility, instrument, and examination methods), moreover it requires that laboratories shall participate proficiency testing(s) and laboratories' examination results shall have traceability of measurements and implement uncertainty of measurement. Implementation of ISO 15189 will result in a significant improvement in medical laboratories management system and their technical competence. The accreditation of medical laboratory will improve medical laboratory service and be useful for patients.

Children with dyslexia show a reduced processing benefit from bimodal speech information compared to their typically developing peers.

Science.gov (United States)

Schaadt, Gesa; van der Meer, Elke; Pannekamp, Ann; Oberecker, Regine; Männel, Claudia

2018-01-17

During information processing, individuals benefit from bimodally presented input, as has been demonstrated for speech perception (i.e., printed letters and speech sounds) or the perception of emotional expressions (i.e., facial expression and voice tuning). While typically developing individuals show this bimodal benefit, school children with dyslexia do not. Currently, it is unknown whether the bimodal processing deficit in dyslexia also occurs for visual-auditory speech processing that is independent of reading and spelling acquisition (i.e., no letter-sound knowledge is required). Here, we tested school children with and without spelling problems on their bimodal perception of video-recorded mouth movements pronouncing syllables. We analyzed the event-related potential Mismatch Response (MMR) to visual-auditory speech information and compared this response to the MMR to monomodal speech information (i.e., auditory-only, visual-only). We found a reduced MMR with later onset to visual-auditory speech information in children with spelling problems compared to children without spelling problems. Moreover, when comparing bimodal and monomodal speech perception, we found that children without spelling problems showed significantly larger responses in the visual-auditory experiment compared to the visual-only response, whereas children with spelling problems did not. Our results suggest that children with dyslexia exhibit general difficulties in bimodal speech perception independently of letter-speech sound knowledge, as apparent in altered bimodal speech perception and lacking benefit from bimodal information. This general deficit in children with dyslexia may underlie the previously reported reduced bimodal benefit for letter-speech sound combinations and similar findings in emotion perception. Copyright © 2018 Elsevier Ltd. All rights reserved.

Intermediate species measurement during iso-butanol auto-ignition

KAUST Repository

Ji, Weiqi

2015-10-01

© 2015 The Combustion Institute.Published by Elsevier Inc. All rights reserved. This work presents the time histories of intermediate species during the auto-ignition of iso-butanol at high pressure and intermediate temperature conditions obtained using a rapid compression machine and recently developed fast sampling system. Iso-butanol ignition delays were acquired for iso-butanol/O2 mixture with an inert/O2 ratio of 7.26, equivalence ratio of 0.4, in the temperature range of 840-950 K and at pressure of 25 bar. Fast sampling and gas chromatography were used to acquire and quantify the intermediate species during the ignition delay of the same mixture at P = 25.3 bar and T = 905 K. The ignition delay times and quantitative measurements of the mole fraction time histories of methane, ethene, propene, iso-butene, iso-butyraldehyde, iso-butanol, and carbon monoxide were compared with predictions from the detailed mechanisms developed by Sarathy et al., Merchant et al., and Cai et al. It is shown that while the Sarathy mechanism well predicts the overall ignition delay time, it overpredicts ethene by a factor of 6-10, underpredicts iso-butene by a factor of 2, and overpredicts iso-butyraldehyde by a factor of 2. Reaction path and sensitivity analyses were carried out to identify the reactions responsible for the observed inadequacy. The rates of iso-butanol hydrogen atom abstraction by OH radical and the beta-scission reactions of hydroxybutyl radicals were updated based on recently published quantum calculation results. Significant improvements were achieved in predicting ignition delay at high pressures (25 and 30 bar) and the species concentrations of ethene and iso-butene. However, the updated mechanism still overpredicts iso-butyraldehyde concentrations. Also, the updated mechanism degrades the prediction in ignition delay at lower pressure (15 bar) compared to the original mechanism developed by Sarathy et al.

Intermediate species measurement during iso-butanol auto-ignition

KAUST Repository

Ji, Weiqi; Zhang, Peng; He, Tanjin; Wang, Zhi; Tao, Ling; He, Xin; Law, Chung K.

2015-01-01

© 2015 The Combustion Institute.Published by Elsevier Inc. All rights reserved. This work presents the time histories of intermediate species during the auto-ignition of iso-butanol at high pressure and intermediate temperature conditions obtained using a rapid compression machine and recently developed fast sampling system. Iso-butanol ignition delays were acquired for iso-butanol/O2 mixture with an inert/O2 ratio of 7.26, equivalence ratio of 0.4, in the temperature range of 840-950 K and at pressure of 25 bar. Fast sampling and gas chromatography were used to acquire and quantify the intermediate species during the ignition delay of the same mixture at P = 25.3 bar and T = 905 K. The ignition delay times and quantitative measurements of the mole fraction time histories of methane, ethene, propene, iso-butene, iso-butyraldehyde, iso-butanol, and carbon monoxide were compared with predictions from the detailed mechanisms developed by Sarathy et al., Merchant et al., and Cai et al. It is shown that while the Sarathy mechanism well predicts the overall ignition delay time, it overpredicts ethene by a factor of 6-10, underpredicts iso-butene by a factor of 2, and overpredicts iso-butyraldehyde by a factor of 2. Reaction path and sensitivity analyses were carried out to identify the reactions responsible for the observed inadequacy. The rates of iso-butanol hydrogen atom abstraction by OH radical and the beta-scission reactions of hydroxybutyl radicals were updated based on recently published quantum calculation results. Significant improvements were achieved in predicting ignition delay at high pressures (25 and 30 bar) and the species concentrations of ethene and iso-butene. However, the updated mechanism still overpredicts iso-butyraldehyde concentrations. Also, the updated mechanism degrades the prediction in ignition delay at lower pressure (15 bar) compared to the original mechanism developed by Sarathy et al.

Estimation of Bimodal Urban Link Travel Time Distribution and Its Applications in Traffic Analysis

Directory of Open Access Journals (Sweden)

Yuxiong Ji

2015-01-01

Full Text Available Vehicles travelling on urban streets are heavily influenced by traffic signal controls, pedestrian crossings, and conflicting traffic from cross streets, which would result in bimodal travel time distributions, with one mode corresponding to travels without delays and the other travels with delays. A hierarchical Bayesian bimodal travel time model is proposed to capture the interrupted nature of urban traffic flows. The travel time distributions obtained from the proposed model are then considered to analyze traffic operations and estimate travel time distribution in real time. The advantage of the proposed bimodal model is demonstrated using empirical data, and the results are encouraging.

Aplikace ISO norem v oblasti vývoje softwaru

OpenAIRE

Ullrich, Jan

2007-01-01

Thesis evaluates ISO standars used for software developement and their relationship to methodologies. It also describes processes according to international standard ISO/IEC 12207 and quality management systems according to ISO 9000. It evaluates also mothodlogy RUP and agile methodollogies. The goal of the thesis to tailor processes related to ISO 9001 to be compliant to the ISO/IEC 12207 in a small company.

Evolution of twinning in extruded AZ31 alloy with bimodal grain structure

Energy Technology Data Exchange (ETDEWEB)

Garcés, G., E-mail: ggarces@cenim.csic.es [Department of Physical Metallurgy, National Centre for Metallurgical Research CENIM-CSIC, Av. De Gregorio del Amo 8, 28040 Madrid (Spain); Oñorbe, E. [CIEMAT, Division of Structural Materials, Avenida Complutense, 40, 28040 Madrid (Spain); Gan, W. [German Engineering Materials Science Centre at MLZ, Helmholtz-Zentrum Geesthacht, Lichtebergstr. 1, D-85747 Garching (Germany); Máthis, K. [Department of Physics of Materials, Faculty of Mathematics and Physics, Charles University, KeKarlovu 5, 121 16 Praha 2 (Czech Republic); Tolnai, D. [Institute of Materials Research, Helmholtz-Zentrum Geesthacht, Max-Planck-Str. 1, 21502 Geesthacht (Germany); Horváth, K. [Department of Physics of Materials, Faculty of Mathematics and Physics, Charles University, KeKarlovu 5, 121 16 Praha 2 (Czech Republic); Pérez, P.; Adeva, P. [Department of Physical Metallurgy, National Centre for Metallurgical Research CENIM-CSIC, Av. De Gregorio del Amo 8, 28040 Madrid (Spain)

2017-04-15

Twinning in extruded AZ31 alloy with a bimodal grain structure is studied under compression along the extrusion direction. This study has combined in-situ measurements during the compression tests by Synchrotron Radiation Diffraction and Acoustic Emission techniques and the evaluation of the microstructure and texture in post-mortem compression samples deformed at different strains. The microstructure of the alloy is characterized by the coexistence of large areas of fine dynamic recrystallized grains and coarse non-recrystallized grains elongated along extrusion direction. Twinning occurs initially in large elongated grains before the macroscopic yield stress which is controlled by the twinning in equiaxed dynamically recrystallized grains. - Highlights: • The AZ31 extruded at low temperature exhibits a bimodal grains structure. • Twinning takes place before macroscopic yielding in coarse non-DRXed grains. • DRXed grains controls the beginning of plasticity in magnesium alloys with bimodal grain structure.

Transfer learning for bimodal biometrics recognition

Science.gov (United States)

Dan, Zhiping; Sun, Shuifa; Chen, Yanfei; Gan, Haitao

2013-10-01

Biometrics recognition aims to identify and predict new personal identities based on their existing knowledge. As the use of multiple biometric traits of the individual may enables more information to be used for recognition, it has been proved that multi-biometrics can produce higher accuracy than single biometrics. However, a common problem with traditional machine learning is that the training and test data should be in the same feature space, and have the same underlying distribution. If the distributions and features are different between training and future data, the model performance often drops. In this paper, we propose a transfer learning method for face recognition on bimodal biometrics. The training and test samples of bimodal biometric images are composed of the visible light face images and the infrared face images. Our algorithm transfers the knowledge across feature spaces, relaxing the assumption of same feature space as well as same underlying distribution by automatically learning a mapping between two different but somewhat similar face images. According to the experiments in the face images, the results show that the accuracy of face recognition has been greatly improved by the proposed method compared with the other previous methods. It demonstrates the effectiveness and robustness of our method.

Peningkatan Mutu Proses Perguruan Tinggi Melalui Sistem Mutu Iso 9000

Directory of Open Access Journals (Sweden)

Th. Widia Soerjaningsih

2004-09-01

Full Text Available Article was made to answer these several questions;  what is acreditation and the application in the college; what is ISO 9000 quality system; why is ISO 9000 needed by the college; how ISO 9000 can support the achievement of the defined quality level; how ISO  9000 guarantee the achievement of BAN target including quality, efficiency, and relevance; what is the difference between BAN Acreditation and ISO 9000 Certification; ISO 9000 Consultant: why it is necessary, how to choose it, the line of the contract; ISO 9000 Assessor and the achieve certification: SGS and etc.; and ISO 9000 Certification Proccess Cost Aspect.   

ISO science - observations of dusty discs.

Science.gov (United States)

Heske, A.

1992-12-01

ISO, the Infrared Space Observatory, will be an infrared observing facility in space. Via submission of observing proposals, use of this facility will be open to the astronomical community. The scientific payload consists of two spectrometers, a camera and a photo-polarimeter. Following an overview of the ISO mission, this paper describes the highlights of the Central Programme - proposals which are being prepared by the instrument groups, the mission scientists and the astronomers of the ISO Science Operations Team - with special emphasis on the proposals concerned with dusty discs.

Launching the chaotic realm of iso-fractals: A short remark

Energy Technology Data Exchange (ETDEWEB)

O' Schmidt, Nathan [Department of Mathematics, Boise State University, 1910 University Drive, Boise, ID 83725 (United States); Katebi, Reza [Department of Physics, California State University in Fullerton, 800 North State College Boulevard, Fullerton, CA 92831 (United States); Corda, Christian [Institute for Theoretical Physics and Advanced Mathematics Einstein-Galilei (IFM), Via Santa Gonda 14, 59100 Prato (Italy)

2015-03-10

In this brief note, we introduce the new, emerging sub-discipline of iso-fractals by highlighting and discussing the preliminary results of recent works. First, we note the abundance of fractal, chaotic, non-linear, and self-similar structures in nature while emphasizing the importance of studying such systems because fractal geometry is the language of chaos. Second, we outline the iso-fractal generalization of the Mandelbrot set to exemplify the newly generated Mandelbrot iso-sets. Third, we present the cutting-edge notion of dynamic iso-spaces and explain how a mathematical space can be iso-topically lifted with iso-unit functions that (continuously or discretely) change; in the discrete case examples, we mention that iteratively generated sequences like Fibonacci’s numbers and (the complex moduli of) Mandelbrot’s numbers can supply a deterministic chain of iso-units to construct an ordered series of (magnified and/or de-magnified) iso-spaces that are locally iso-morphic. Fourth, we consider the initiation of iso-fractals with Inopin’s holographic ring (IHR) topology and fractional statistics for 2D and 3D iso-spaces. In total, the reviewed iso-fractal results are a significant improvement over traditional fractals because the application of Santilli’s iso-mathematics arms us an extra degree of freedom for attacking problems in chaos. Finally, we conclude by proposing some questions and ideas for future research work.

Lessons learned with ISO 14001 at DOE sites

Energy Technology Data Exchange (ETDEWEB)

Wilkinson, C. H., LLNL

1998-03-01

ISO 14001 is the international standard for environmental management systems (EMS). The standard applies the `plan, do, check, act` management system model to assure that the environmental impacts of operations are fully considered in planning and facility operations. ISO 14001 has grown in popularity in both the public and the private sector and has seen increasing utility within the U.S. Department of Energy (DOE). While there is no final DOE policy or requirement for ISO 14001 EMS implementation, ISO 14001 commands an active presence at many DOE sites. In general, the impetus for ISO 14001 in the DOE complex has been either an initiative by site management contractors to improve performance, or an actual requirement in the new management contracts for the sites. Several DOE sites now are committed to implement EMS`s in conformance with ISO 14001: Brookhaven National Laboratory (BNL), Hanford, Idaho National Engineering and Environmental Laboratory (INEEL), Kansas City Plant, Nevada Test Site, Savannah River Site (SRS), Waste Isolation Pilot Project (WIPP), West Valley. Several other DOE sites are expected to proceed in the near future with an EMS consistent with ISO 14001. However, not all sites are proceeding with an ISO 14001 EMS based on individual site business considerations. This paper describes the status of EMS implementation at these sites and identifies lessons learned that may be of use to other DOE sites.

TRACING OUTFLOWS AND ACCRETION: A BIMODAL AZIMUTHAL DEPENDENCE OF Mg II ABSORPTION

International Nuclear Information System (INIS)

Kacprzak, Glenn G.; Churchill, Christopher W.; Nielsen, Nikole M.

2012-01-01

We report a bimodality in the azimuthal angle distribution of gas around galaxies as traced by Mg II absorption: halo gas prefers to exist near the projected galaxy major and minor axes. The bimodality is demonstrated by computing the mean azimuthal angle probability distribution function using 88 spectroscopically confirmed Mg II-absorption-selected galaxies [W r (2796) ≥ 0.1 Å] and 35 spectroscopically confirmed non-absorbing galaxies [W r (2796) r (2796) r (2796) distribution for gas along the major axis is likely skewed toward weaker Mg II absorption than for gas along the projected minor axis. These combined results are highly suggestive that the bimodality is driven by gas accreted along the galaxy major axis and outflowing along the galaxy minor axis. Adopting these assumptions, we find that the opening angle of outflows and inflows to be 100° and 40°, respectively. We find that the probability of detecting outflows is ∼60%, implying that winds are more commonly observed.

Nano-scale simulation based study of creep behavior of bimodal nanocrystalline face centered cubic metal.

Science.gov (United States)

Meraj, Md; Pal, Snehanshu

2017-10-11

In this paper, the creep behavior of nanocrystalline Ni having bimodal grain structure is investigated using molecular dynamics simulation. Analysis of structural evolution during the creep process has also been performed. It is observed that an increase in size of coarse grain causes improvement in creep properties of bimodal nanocrystalline Ni. Influence of bimodality (i.e., size difference between coarse and fine grains) on creep properties are found to be reduced with increasing creep temperature. The dislocation density is observed to decrease exponentially with progress of creep deformation. Grain boundary diffusion controlled creep mechanism is found to be dominant at the primary creep region and the initial part of the secondary creep region. After that shear diffusion transformation mechanism is found to be significantly responsible for deformation as bimodal nanocrystalline Ni transforms to amorphous structure with further progress of the creep process. The presence of , , and  distorted icosahedra has a significant influence on creep rate in the tertiary creep regime according to Voronoi cluster analysis.

Does bimodal stimulus presentation increase ERP components usable in BCIs?

Science.gov (United States)

Thurlings, Marieke E.; Brouwer, Anne-Marie; Van Erp, Jan B. F.; Blankertz, Benjamin; Werkhoven, Peter J.

2012-08-01

Event-related potential (ERP)-based brain-computer interfaces (BCIs) employ differences in brain responses to attended and ignored stimuli. Typically, visual stimuli are used. Tactile stimuli have recently been suggested as a gaze-independent alternative. Bimodal stimuli could evoke additional brain activity due to multisensory integration which may be of use in BCIs. We investigated the effect of visual-tactile stimulus presentation on the chain of ERP components, BCI performance (classification accuracies and bitrates) and participants’ task performance (counting of targets). Ten participants were instructed to navigate a visual display by attending (spatially) to targets in sequences of either visual, tactile or visual-tactile stimuli. We observe that attending to visual-tactile (compared to either visual or tactile) stimuli results in an enhanced early ERP component (N1). This bimodal N1 may enhance BCI performance, as suggested by a nonsignificant positive trend in offline classification accuracies. A late ERP component (P300) is reduced when attending to visual-tactile compared to visual stimuli, which is consistent with the nonsignificant negative trend of participants’ task performance. We discuss these findings in the light of affected spatial attention at high-level compared to low-level stimulus processing. Furthermore, we evaluate bimodal BCIs from a practical perspective and for future applications.

RSMASS-D nuclear thermal propulsion and bimodal system mass models

Science.gov (United States)

King, Donald B.; Marshall, Albert C.

1997-01-01

Two relatively simple models have been developed to estimate reactor, radiation shield, and balance of system masses for a particle bed reactor (PBR) nuclear thermal propulsion concept and a cermet-core power and propulsion (bimodal) concept. The approach was based on the methodology developed for the RSMASS-D models. The RSMASS-D approach for the reactor and shield sub-systems uses a combination of simple equations derived from reactor physics and other fundamental considerations along with tabulations of data from more detailed neutron and gamma transport theory computations. Relatively simple models are used to estimate the masses of other subsystem components of the nuclear propulsion and bimodal systems. Other subsystem components include instrumentation and control (I&C), boom, safety systems, radiator, thermoelectrics, heat pipes, and nozzle. The user of these models can vary basic design parameters within an allowed range to achieve a parameter choice which yields a minimum mass for the operational conditions of interest. Estimated system masses are presented for a range of reactor power levels for propulsion for the PBR propulsion concept and for both electrical power and propulsion for the cermet-core bimodal concept. The estimated reactor system masses agree with mass predictions from detailed calculations with xx percent for both models.

The international ISOE programme. ISOE IAEA technical centre activities

International Nuclear Information System (INIS)

Gustafsson, M.

1996-01-01

The objective of the sub-programme on Occupational Radiation Protection in the International Atomic Energy Agency, IAEA, is to promote a harmonized approach to optimizing occupational radiation protection by developing guidelines for controlling radiation doses in the workplace and on current occupational radiation protection techniques. A significant part of this programme is the provision of assistance to developing member states to bring their radiation safety infrastructure to an appropriate level for the usage of radiation in the state. In consistence with these objectives the IAEA has been involved with the ISOE programme from its inception and has contributed actively to its growth. In 1993 an arrangement was agreed between the IAEA and the Nuclear Energy Agency, NEA, by which the IAEA co-sponsors ISOE inviting those IAEA member states which are not members of the NEA to participate cost-free in the programme. (author)

A graded approach to ISO 9000 implementation for records managers

Energy Technology Data Exchange (ETDEWEB)

Pasterczyk, C.E.

1994-08-01

ISO 9000 is a series of quality system standards developed by Technical Committee 176 of the International Standards Organization. The series includes three standards, ISO 9001 `Quality systems--Model for quality assurance in design/development, production, installation and serving,` ISO 9002 `Quality systems--Model for quality assurance in production and installation,` ISO 9003 `Quality systems--Model for quality assurance in final inspection and test,` and two guidelines, ISO 9000 `Quality management and quality assurance standards` and ISO 9004 `Quality management and quality system elements--Guidelines.` In companies with quality programs already in place, the structure of the ISO series lends itself to augmenting those policies, procedures, and instructions where problems exist or where the risks of failure are greater. The objectives of this paper are to provide a basic familiarity to ISO 9000 and quality assurance concepts; provide a higher level of familiarity to the records management and document control portions of the ISO 9000 series; and to discuss a graded approach to meeting the intent of ISO 9000.

ISO 14001

DEFF Research Database (Denmark)

Jørgensen, Tine Herreborg

2004-01-01

The aim of this paper is to discuss a number of issues related to ISO 14001, the international standard for environmental management systems (EMS). The standard is a process standard that leaves room for interpretation at company level as well as among lead auditors from certifying bodies...

Risk in Management Systems according to ISO standard

Directory of Open Access Journals (Sweden)

P. Królas

2010-07-01

Full Text Available The purpose of this article was to present selected management standards in context of risk management. It presents main ISOmanagement standards (ISO 9001, ISO 14001, OHSAS 18001, ISO 27001, BS 25999, ISO 31000 that apply to polish enterprises. In thefirst part of this article there are analyzed management standards regarding quality, environment, occupational health and safety,information security, as well as business continuity management and risk management. The second part of the article discusses the processof dealing with risk based on chosen management standard.

Implementation and Impact of ISO 9001

NARCIS (Netherlands)

B. Manders (Basak)

2015-01-01

markdownabstract__Abstract __ The ISO 9001 quality management standard has been implemented by more than one million organizations in 187 countries since its introduction in 1987. A newer version of ISO 9001 is planned to be introduced in 2015. Even though it is widely used by organizations to

Are star formation rates of galaxies bimodal?

Science.gov (United States)

Feldmann, Robert

2017-09-01

Star formation rate (SFR) distributions of galaxies are often assumed to be bimodal with modes corresponding to star-forming and quiescent galaxies, respectively. Both classes of galaxies are typically studied separately, and SFR distributions of star-forming galaxies are commonly modelled as lognormals. Using both observational data and results from numerical simulations, I argue that this division into star-forming and quiescent galaxies is unnecessary from a theoretical point of view and that the SFR distributions of the whole population can be well fitted by zero-inflated negative binomial distributions. This family of distributions has three parameters that determine the average SFR of the galaxies in the sample, the scatter relative to the star-forming sequence and the fraction of galaxies with zero SFRs, respectively. The proposed distributions naturally account for (I) the discrete nature of star formation, (II) the presence of 'dead' galaxies with zero SFRs and (III) asymmetric scatter. Excluding 'dead' galaxies, the distribution of log SFR is unimodal with a peak at the star-forming sequence and an extended tail towards low SFRs. However, uncertainties and biases in the SFR measurements can create the appearance of a bimodal distribution.

Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans.

Science.gov (United States)

Marks, Kendra L; Martel, David T; Wu, Calvin; Basura, Gregory J; Roberts, Larry E; Schvartz-Leyzac, Kara C; Shore, Susan E

2018-01-03

The dorsal cochlear nucleus is the first site of multisensory convergence in mammalian auditory pathways. Principal output neurons, the fusiform cells, integrate auditory nerve inputs from the cochlea with somatosensory inputs from the head and neck. In previous work, we developed a guinea pig model of tinnitus induced by noise exposure and showed that the fusiform cells in these animals exhibited increased spontaneous activity and cross-unit synchrony, which are physiological correlates of tinnitus. We delivered repeated bimodal auditory-somatosensory stimulation to the dorsal cochlear nucleus of guinea pigs with tinnitus, choosing a stimulus interval known to induce long-term depression (LTD). Twenty minutes per day of LTD-inducing bimodal (but not unimodal) stimulation reduced physiological and behavioral evidence of tinnitus in the guinea pigs after 25 days. Next, we applied the same bimodal treatment to 20 human subjects with tinnitus using a double-blinded, sham-controlled, crossover study. Twenty-eight days of LTD-inducing bimodal stimulation reduced tinnitus loudness and intrusiveness. Unimodal auditory stimulation did not deliver either benefit. Bimodal auditory-somatosensory stimulation that induces LTD in the dorsal cochlear nucleus may hold promise for suppressing chronic tinnitus, which reduces quality of life for millions of tinnitus sufferers worldwide. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Brain deactivation in the outperformance in bimodal tasks: an FMRI study.

Directory of Open Access Journals (Sweden)

Tzu-Ching Chiang

Full Text Available While it is known that some individuals can effectively perform two tasks simultaneously, other individuals cannot. How the brain deals with performing simultaneous tasks remains unclear. In the present study, we aimed to assess which brain areas corresponded to various phenomena in task performance. Nineteen subjects were requested to sequentially perform three blocks of tasks, including two unimodal tasks and one bimodal task. The unimodal tasks measured either visual feature binding or auditory pitch comparison, while the bimodal task required performance of the two tasks simultaneously. The functional magnetic resonance imaging (fMRI results are compatible with previous studies showing that distinct brain areas, such as the visual cortices, frontal eye field (FEF, lateral parietal lobe (BA7, and medial and inferior frontal lobe, are involved in processing of visual unimodal tasks. In addition, the temporal lobes and Brodmann area 43 (BA43 were involved in processing of auditory unimodal tasks. These results lend support to concepts of modality-specific attention. Compared to the unimodal tasks, bimodal tasks required activation of additional brain areas. Furthermore, while deactivated brain areas were related to good performance in the bimodal task, these areas were not deactivated where the subject performed well in only one of the two simultaneous tasks. These results indicate that efficient information processing does not require some brain areas to be overly active; rather, the specific brain areas need to be relatively deactivated to remain alert and perform well on two tasks simultaneously. Meanwhile, it can also offer a neural basis for biofeedback in training courses, such as courses in how to perform multiple tasks simultaneously.

How bilingualism protects the brain from aging: Insights from bimodal bilinguals.

Science.gov (United States)

Li, Le; Abutalebi, Jubin; Emmorey, Karen; Gong, Gaolang; Yan, Xin; Feng, Xiaoxia; Zou, Lijuan; Ding, Guosheng

2017-08-01

Bilingual experience can delay cognitive decline during aging. A general hypothesis is that the executive control system of bilinguals faces an increased load due to controlling two languages, and this increased load results in a more "tuned brain" that eventually creates a neural reserve. Here we explored whether such a neuroprotective effect is independent of language modality, i.e., not limited to bilinguals who speak two languages but also occurs for bilinguals who use a spoken and a signed language. We addressed this issue by comparing bimodal bilinguals to monolinguals in order to detect age-induced structural brain changes and to determine whether we can detect the same beneficial effects on brain structure, in terms of preservation of gray matter volume (GMV), for bimodal bilinguals as has been reported for unimodal bilinguals. Our GMV analyses revealed a significant interaction effect of age × group in the bilateral anterior temporal lobes, left hippocampus/amygdala, and left insula where bimodal bilinguals showed slight GMV increases while monolinguals showed significant age-induced GMV decreases. We further found through cortical surface-based measurements that this effect was present for surface area and not for cortical thickness. Moreover, to further explore the hypothesis that overall bilingualism provides neuroprotection, we carried out a direct comparison of GMV, extracted from the brain regions reported above, between bimodal bilinguals, unimodal bilinguals, and monolinguals. Bilinguals, regardless of language modality, exhibited higher GMV compared to monolinguals. This finding highlights the general beneficial effects provided by experience handling two language systems, whether signed or spoken. Hum Brain Mapp 38:4109-4124, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

The Efficiency of the Bimodal System Transportation

Directory of Open Access Journals (Sweden)

Nada Štrumberger

2012-10-01

Full Text Available The development of fast railway results in an increased applicationof Trailer Train bimodal system transportation. Thetraffic costs are multiply reduced, particularly the variablecosts. On the other hand the environmental pollution from exhaustgases is also reduced. Therefore, by the year 2010 cargotransport should be preponderant~v used which would be characterisedby fast electric trains producing less noise, at lowercosts and with clean environment.

The new international standard ISO 14001: 2004 environmental management system

International Nuclear Information System (INIS)

Oheba, Jamal Basher

2006-01-01

ISO 14001 is one standard in the ISO 14000 series of standards developed by International Organization of Standardization (ISO). Since it was published in 19096, it has rapidly become the most important environmental standard in the world. ISO 14001 is an environmental management system (EMS) that can be classified into environmental technologies provides a systematic procedure to all kind of organizations to prevent pollutions, protect environment and to improve their overall environmental performance. This new standard ISO 14001 2004 was published on November 15, 2004. It cancels and replaced the old ISO 14001-1996. Because the important of the previous standard for our local industries, firms, ...etc, this paper presents ISO 14001 concepts, issues, benefits and focuses on the stages of implementation to achieve ISO 14001-2004 certification which includes general requirements environmental policy, planning (objectives, targets ..), implementation and operations, checking and management review ...etc and presents how to apply isotop time saver software to design records, and to save time to implement ISO 14001 2004 and finally a conclusion is provided.(Author)

Application Security in the ISO27001 Environment

CERN Document Server

Vinod, Vasudevan; Firosh, Ummer

2008-01-01

Application Security in the ISO27001 Environment demonstrates how to secure software applications within a best practice ISO/IEC 27001 environment and supports implementation of the PCI DSS Payment Application Security Standard.

Tietoturvallisuusauditointi ISO 27000-viitekehyksessä

OpenAIRE

Luoma, Ilmari

2015-01-01

Tiedon olemassaolo eri olomuodoissa muodostaa vaikeasti hallittavan uhkakentän, jonka käsittelyyn kansainvälisesti hyväksytty ISO 27000 -standardi on hyvä väline. Työn tarkoitus on perehtyä ISO/IEC 27000 -standardisarjaan, soveltaa standardin vaatimuksia laatimalla tietoturvallisuuden auditointiaineisto ja -menetelmä, sekä toteuttaa tietoturvallisuusauditointi käytännössä. Työssä esitellään tietoturvallisuuden kytkeytyminen yritysturvallisuuteen, tietoturvallisuuden osa-alueittainen ...

Application of a bi-modal PBR nuclear propulsion and power system to military missions

Science.gov (United States)

Venetoklis, Peter S.

1995-01-01

The rapid proliferation of arms technology and space access combined with current economic realities in the United States are creating ever greater demands for more capable space-based military assets. The paper illustrates that bi-modal nuclear propulsion and power based on the Particle Bed Reactor (PBR) is a high-leverage tehcnology that can maximize utility while minimizing cost. Mission benefits offered by the bi-modal PBR, including enhanced maneuverability, lifetime, survivability, payload power, and operational flexibility, are discussed. The ability to deliver desired payloads on smaller boosters is also illustrated. System descriptions and parameters for 10 kWe and 100 kWe power output levels are summarized. It is demonstrated via design exercise that bi-modal PBR dramtically enhances performance of a military satellite in geosynchronous orbit, increasing payload mass, payload power, and maneuverability.

PENGGABUNGAN PENERAPAN SISTEM JAMINAN MUTU ISO 9001:2008 DAN SISTEM HACCP KE DALAM SISTEM MANAJEMEN KEAMANAN PANGAN ISO 22000:2009 (STUDI KASUS DI PT INDOKOM SAMUDRA PERSADA [The Merger of Quality Assurance System ISO 9001:2008 and HACCP system into Food

Directory of Open Access Journals (Sweden)

Novri Ilmiawan

2014-10-01

Full Text Available The object of this research was to merge the application of HACCP system and ISO 9001:2008 in ISP company into ISO 22000:2009. The  research method used was case study method. The study was conducted on three stages. The first was the arrangement gap analysis conducted by comparing the conditions of the company with ISO 22000:2009 standards. The second was by observing sanitation and pre requisite programs. The third was by observing traceability system. The data in this research were reported descriptively, consisted of ISO 9001:2008 and HACCP application in the company and the gaps of principles in ISO 22000:2009 toward ISO 9001:2008 and HACCP. The result showed that ISP company has applied 12 steps which covered in HACCP system, and also the ISO 9001 system were appropriate with ISO 9001:2008 standards in every clauses. Pre requisite program (GMP and SSOP have been effectively applied. GMP in ISP company is categorized on the first spot (excellent. The eight keys of SSOP have been fulfilled. ISP company has been fulfilling 54 from 57 (94.74% criteria in ISO 22000:2009 standards, yet there still several things needed to be improved, which are the quality manual content  and HACCP table plan and its monitoring. The  traceability system has been applied well in ISP. Keywords : HACCP, ISO 9001, ISO 22000, GMP, SSOP.

Geometry planning and image registration in magnetic particle imaging using bimodal fiducial markers

International Nuclear Information System (INIS)

Werner, F.; Hofmann, M.; Them, K.; Knopp, T.; Jung, C.; Salamon, J.; Kaul, M. G.; Mummert, T.; Adam, G.; Ittrich, H.; Werner, R.; Säring, D.; Weber, O. M.

2016-01-01

Purpose: Magnetic particle imaging (MPI) is a quantitative imaging modality that allows the distribution of superparamagnetic nanoparticles to be visualized. Compared to other imaging techniques like x-ray radiography, computed tomography (CT), and magnetic resonance imaging (MRI), MPI only provides a signal from the administered tracer, but no additional morphological information, which complicates geometry planning and the interpretation of MP images. The purpose of the authors’ study was to develop bimodal fiducial markers that can be visualized by MPI and MRI in order to create MP–MR fusion images. Methods: A certain arrangement of three bimodal fiducial markers was developed and used in a combined MRI/MPI phantom and also during in vivo experiments in order to investigate its suitability for geometry planning and image fusion. An algorithm for automated marker extraction in both MR and MP images and rigid registration was established. Results: The developed bimodal fiducial markers can be visualized by MRI and MPI and allow for geometry planning as well as automated registration and fusion of MR–MP images. Conclusions: To date, exact positioning of the object to be imaged within the field of view (FOV) and the assignment of reconstructed MPI signals to corresponding morphological regions has been difficult. The developed bimodal fiducial markers and the automated image registration algorithm help to overcome these difficulties.

Geometry planning and image registration in magnetic particle imaging using bimodal fiducial markers

Energy Technology Data Exchange (ETDEWEB)

Werner, F., E-mail: f.werner@uke.de; Hofmann, M.; Them, K.; Knopp, T. [Section for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany and Institute for Biomedical Imaging, Hamburg University of Technology, Hamburg 21073 (Germany); Jung, C.; Salamon, J.; Kaul, M. G.; Mummert, T.; Adam, G.; Ittrich, H. [Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 (Germany); Werner, R.; Säring, D. [Institute for Computational Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg 20246 (Germany); Weber, O. M. [Philips Medical Systems DMC GmbH, Hamburg 22335 (Germany)

2016-06-15

Purpose: Magnetic particle imaging (MPI) is a quantitative imaging modality that allows the distribution of superparamagnetic nanoparticles to be visualized. Compared to other imaging techniques like x-ray radiography, computed tomography (CT), and magnetic resonance imaging (MRI), MPI only provides a signal from the administered tracer, but no additional morphological information, which complicates geometry planning and the interpretation of MP images. The purpose of the authors’ study was to develop bimodal fiducial markers that can be visualized by MPI and MRI in order to create MP–MR fusion images. Methods: A certain arrangement of three bimodal fiducial markers was developed and used in a combined MRI/MPI phantom and also during in vivo experiments in order to investigate its suitability for geometry planning and image fusion. An algorithm for automated marker extraction in both MR and MP images and rigid registration was established. Results: The developed bimodal fiducial markers can be visualized by MRI and MPI and allow for geometry planning as well as automated registration and fusion of MR–MP images. Conclusions: To date, exact positioning of the object to be imaged within the field of view (FOV) and the assignment of reconstructed MPI signals to corresponding morphological regions has been difficult. The developed bimodal fiducial markers and the automated image registration algorithm help to overcome these difficulties.

Pluto/Charon exploration utilizing a bi-modal PBR nuclear propulsion/power system

Science.gov (United States)

Venetoklis, Peter S.

1995-01-01

The paper describes a Pluto/Charon orbiter utilizing a bi-modal nuclear propulsion and power system based on the Particle Bed Reactor. The orbiter is sized for launch to Nuclear-Safe orbit atop a Titan IV or equivalent launch veicle. The bi-modal system provides thermal propulsion for Earth orbital departure and Pluto orbital capture, and 10 kWe of electric power for payload functions and for in-system maneuvering with ion thrusters. Ion thrusters are used to perform inclination changes about Pluto, a transfer from low Pluto orbit to low Charon orbit, and inclination changes about charon. A nominal payload can be deliverd in as little as 15 years, 1000 kg in 17 years, and close to 2000 kg in 20 years. Scientific return is enormously aided by the availability of up to 10 kWe, due to greater data transfer rates and more/better instruments. The bi-modal system can provide power at Pluto/Charon for 10 or more years, enabling an extremely robust, scientifically rewarding, and cost-effective exploration mission.

ADOPTION OF ISO 9001 QUALITY MANAGEMENT STANDARD IN AFRICA

Directory of Open Access Journals (Sweden)

Erlantz Allur

2014-03-01

Full Text Available This article analyzes the dissemination of ISO 9001, the main global management standards, within Africa. The work refers to the diffusion of ISO 9001 standard in terms of its certification intensity. In this article, the dissemination of ISO 9001 in Africa has been analyzed. The findings reveal that the diffusion of the standard in this continent is not very relevant, what might be seen as an indicator of the process of Africa's trade marginalization in the age of globalization. The general certification intensity of the continet is of 0.18; in other words, the proportion of the contribution of Africa to the global GDP of the world is more than five times superior to the proportion of ISO 9001 certificates located in Africa. By means of the logistic model the dissemination of ISO 9001 is forecasted, and it has been observed that the diffusion of ISO 9001 in Africa is in an 85% of its saturation point. Taking into account this model, it's expected that the dissemination of ISO 9001 will be growing until 2020.

Verification the 25-kgy dose using the iso standard iso/tr 13409 for the production of bone grafts

International Nuclear Information System (INIS)

Otero, I.; Barrera, L.; Diaz, A.; Napoles, D.; Sanchez, E

2001-01-01

The purpose of this work was to verify the 25 Gy dose using the ISO standard ISO/TR 13409 for the production of bone grafts from the Tissue Bank ORTOP of the Complejo Cientifico Ortopedico Internacional Frank Pais. We performed two principal microbiological activities: bioburden estimate, pre-sterilization count plus a compensation for the efficiency of the recovery method, by ISO 11737-1 and test of sterility by ISO 11737-2. The techniques for Bioburden estimation could be direct or indirect. Choice of direct vs. indirect depends on number of contaminating micro-organisms, product configuration, ability to remove microbial contamination, effect of removal method on microbial viability, types and location of micro-organisms, nature of product and culture conditions. For a test of sterility, he product unit or SIP putted direct immersion in educated culture medium and incubate. Keep precaution to minimize level to the false positives is necessary

ISO 9001 quality management systems

CERN Document Server

Natarajan, Dhanasekharan

2017-01-01

This book explains the requirements of ISO 9001 for establishing quality management system (QMS) for an organization. The requirements are illustrated with examples from industries for understanding the requirements and preparing the documents of QMS with high clarity. Methods of integrating ISO 9001 requirements with enterprise resource planning (ERP) software are presented. The software integrated approach enables process owners to focus on their core tasks of achieving the planned outputs of processes and the software generates quality records automatically.

Lean principles adoption in environmental management system (EMS - ISO 14001

Directory of Open Access Journals (Sweden)

Perumal Puvanasvaran

2012-12-01

Full Text Available Purpose: The purpose of this study is to examine the characteristic of the lean principles into ISO 14001 and to propose linkage of the lean principles and ISO 14001.Design/methodology/approach: To achieve the objective of the study, literature survey and quantitative research method using questionnaires survey are used.Findings and Originality/value: The findings of this study confirm that ISO 14001 certified company adopted lean production practices.  The study also proves that lean principles have positive and significant relationship with ISO 14001 EMS and the linkage can be made between lean principles and ISO 14001 to achieve Continual Improvement.Research limitations/implications: The small sizes of the sample of the participating companies are the main limitations of this study and this research mainly focuses on the manufacturing environment and services industry.Practical implications: This research show that all ISO 14001 companies do adopt at least one lean production practices and the main findings are lean principles has positive and highly significant relationship with ISO 14001 requirements.  This is because the integration of lean principles into ISO 14001 will serve practical methods for ISO14001 EMS to achieve the continual improvement.Originality/value: This research is amongst the first to study the combined lean principles with ISO 1400.  Based on the current situation, there is no integration within this two management system. 

Standardization of Image Quality Analysis – ISO 19264

DEFF Research Database (Denmark)

Wüller, Dietmar; Kejser, Ulla Bøgvad

2016-01-01

There are a variety of image quality analysis tools available for the archiving world, which are based on different test charts and analysis algorithms. ISO has formed a working group in 2012 to harmonize these approaches and create a standard way of analyzing the image quality for archiving...... systems. This has resulted in three documents that have been or are going to be published soon. ISO 19262 defines the terms used in the area of image capture to unify the language. ISO 19263 describes the workflow issues and provides detailed information on how the measurements are done. Last...... but not least ISO 19264 describes the measurements in detail and provides aims and tolerance levels for the different aspects. This paper will present the new ISO 19264 technical specification to analyze image quality based on a single capture of a multi-pattern test chart, and discuss the reasoning behind its...

Twenty new ISO standards on dosimetry for radiation processing

International Nuclear Information System (INIS)

Farrar IV, H.

2000-01-01

Twenty standards on essentially all aspects of dosimetry for radiation processing were published as new ISO standards in December 1998. The standards are based on 20 standard practices and guides developed over the past 14 years by Subcommittee E10.01 of the American Society for Testing and Materials (ASTM). The transformation to ISO standards using the 'fast track' process under ISO Technical Committee 85 (ISO/TC85) commenced in 1995 and resulted in some overlap of technical information between three of the new standards and the existing ISO Standard 11137 Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. Although the technical information in these four standards was consistent, compromise wording in the scopes of the three new ISO standards to establish precedence for use were adopted. Two of the new ISO standards are specifically for food irradiation applications, but the majority apply to all forms of gamma, X-ray, and electron beam radiation processing, including dosimetry for sterilization of health care products and the radiation processing of fruit, vegetables, meats, spices, processed foods, plastics, inks, medical wastes, and paper. Most of the standards provide exact procedures for using individual dosimetry systems or for characterizing various types of irradiation facilities, but one covers the selection and calibration of dosimetry systems, and another covers the treatment of uncertainties using the new ISO Type A and Type B evaluations. Unfortunately, nine of the 20 standards just adopted by the ISO are not the most recent versions of these standards and are therefore already out of date. To help solve this problem, efforts are being made to develop procedures to coordinate the ASTM and ISO development and revision processes for these and future ASTM-originating dosimetry standards. In the meantime, an additional four dosimetry standards have recently been published by the ASTM but have

A Stepwise ISO-Based TQM Implementation Approach Using ISO 9001:2015

Directory of Open Access Journals (Sweden)

Chen Chi-kuang

2016-12-01

Full Text Available The lack of an implementation roadmap always deters enterprises from choosing Total Quality Management (TQM as its major management approach. This paper proposes a stepwise ISO-based TQM implementation approach which is based on the notion of the new three-dimensional overall business excellence framework developed by Dahlgaard et al. [1]. The proposed approach consists of nine steps comprising three categories: “TQM faith building”, “TQM tools and techniques learning”, and “system development”. The steps in each of the three categories are arranged to span across the proposed nine-step approach. The ISO 9001:2015 standard is used as a case study to demonstrate the proposed approach. The ideas and benefits of the proposed approach are further discussed in relation to this illustration.

New ISO standard - personnel photographic film dosemeters

International Nuclear Information System (INIS)

Brabec, D.

1980-01-01

The ISO Standard 1757 ''Personnel Photographic Film Dosemeters'', issued in June 1980, is briefly described. UVVVR's own dosemeter developed for use in the national film dosimetry service in Czechoslovakia is evaluated in relation to this ISO Standard. (author)

Near-Infrared Squaraine Dye Encapsulated Micelles for in Vivo Fluorescence and Photoacoustic Bimodal Imaging.

Science.gov (United States)

Sreejith, Sivaramapanicker; Joseph, James; Lin, Manjing; Menon, Nishanth Venugopal; Borah, Parijat; Ng, Hao Jun; Loong, Yun Xian; Kang, Yuejun; Yu, Sidney Wing-Kwong; Zhao, Yanli

2015-06-23

Combined near-infrared (NIR) fluorescence and photoacoustic imaging techniques present promising capabilities for noninvasive visualization of biological structures. Development of bimodal noninvasive optical imaging approaches by combining NIR fluorescence and photoacoustic tomography demands suitable NIR-active exogenous contrast agents. If the aggregation and photobleaching are prevented, squaraine dyes are ideal candidates for fluorescence and photoacoustic imaging. Herein, we report rational selection, preparation, and micelle encapsulation of an NIR-absorbing squaraine dye (D1) for in vivo fluorescence and photoacoustic bimodal imaging. D1 was encapsulated inside micelles constructed from a biocompatible nonionic surfactant (Pluoronic F-127) to obtain D1-encapsulated micelles (D1(micelle)) in aqueous conditions. The micelle encapsulation retains both the photophysical features and chemical stability of D1. D1(micelle) exhibits high photostability and low cytotoxicity in biological conditions. Unique properties of D1(micelle) in the NIR window of 800-900 nm enable the development of a squaraine-based exogenous contrast agent for fluorescence and photoacoustic bimodal imaging above 820 nm. In vivo imaging using D1(micelle), as demonstrated by fluorescence and photoacoustic tomography experiments in live mice, shows contrast-enhanced deep tissue imaging capability. The usage of D1(micelle) proven by preclinical experiments in rodents reveals its excellent applicability for NIR fluorescence and photoacoustic bimodal imaging.

Penetration in bimodal, polydisperse granular material

KAUST Repository

Kouraytem, Nadia; Thoroddsen, Sigurdur T; Marston, J. O.

2016-01-01

We investigate the impact penetration of spheres into granular media which are compositions of two discrete size ranges, thus creating a polydisperse bimodal material. We examine the penetration depth as a function of the composition (volume fractions of the respective sizes) and impact speed. Penetration depths were found to vary between delta = 0.5D(0) and delta = 7D(0), which, for mono-modal media only, could be correlated in terms of the total drop height, H = h + delta, as in previous studies, by incorporating correction factors for the packing fraction. Bimodal data can only be collapsed by deriving a critical packing fraction for each mass fraction. The data for the mixed grains exhibit a surprising lubricating effect, which was most significant when the finest grains [d(s) similar to O(30) mu m] were added to the larger particles [d(l) similar to O(200 - 500) mu m], with a size ratio, epsilon = d(l)/d(s), larger than 3 and mass fractions over 25%, despite the increased packing fraction. We postulate that the small grains get between the large grains and reduce their intergrain friction, only when their mass fraction is sufficiently large to prevent them from simply rattling in the voids between the large particles. This is supported by our experimental observations of the largest lubrication effect produced by adding small glass beads to a bed of large sand particles with rough surfaces.

Penetration in bimodal, polydisperse granular material

KAUST Repository

Kouraytem, N.

2016-11-07

We investigate the impact penetration of spheres into granular media which are compositions of two discrete size ranges, thus creating a polydisperse bimodal material. We examine the penetration depth as a function of the composition (volume fractions of the respective sizes) and impact speed. Penetration depths were found to vary between delta = 0.5D(0) and delta = 7D(0), which, for mono-modal media only, could be correlated in terms of the total drop height, H = h + delta, as in previous studies, by incorporating correction factors for the packing fraction. Bimodal data can only be collapsed by deriving a critical packing fraction for each mass fraction. The data for the mixed grains exhibit a surprising lubricating effect, which was most significant when the finest grains [d(s) similar to O(30) mu m] were added to the larger particles [d(l) similar to O(200 - 500) mu m], with a size ratio, epsilon = d(l)/d(s), larger than 3 and mass fractions over 25%, despite the increased packing fraction. We postulate that the small grains get between the large grains and reduce their intergrain friction, only when their mass fraction is sufficiently large to prevent them from simply rattling in the voids between the large particles. This is supported by our experimental observations of the largest lubrication effect produced by adding small glass beads to a bed of large sand particles with rough surfaces.

SINERGI ISO 9001:2000 - CMMI PADA INDUSTRI PENGEMBANG PERANGKAT LUNAK

Directory of Open Access Journals (Sweden)

Leo Willyanto Santoso

2005-01-01

Full Text Available All sectors of society including softwere industry, have a big concern about quality, both of product quality and service quality. The need to manage risk, has a strong relation with quality and increases system complexity. Standarization in determining quality, ISO is a must for all software developer. If we study further, ISO 9001:2000 still has some weakness especially for implementation in software product. This paper presents a comparative analysis of quality approaches to risk management. This paper also provide a general overview of all the risks aspects treated in ISO 9001:2000 standards and CMMI model version 1.1. In this research, we obtain a strategy to implement ISO 9001:2000 and CMMI together when we make a planing to increase software process. Besides it produces analysis how to change position from ISO 9001:2000 to CMMI. In the implementation on software industry PT 'X', obtain get various benefits that has never been obtained before. Abstract in Bahasa Indonesia : Semua hal dalam hidup ini selalu memperhatikan masalah kualitas, baik itu berupa kualitas produk ataupun kualitas layanan. Pada industri perangkat lunak, hal ini tidak dibedakan, kebutuhan untuk menghasilkan produk yang berkualitas akan meningkatkan kekompleksan dari sebuah sistem. Standarisasi dalam penentuan kualitas, ISO sudah menjadi keharusan bagi para pengembang perangkat lunak. Apabila diteliti lebih lanjut, ISO 9001:2000 masih mempunyai banyak kekurangan, khususnya untuk diaplikasikan dalam produk perangkat lunak.Pada penelitian ini, akan dibahas analisis perbandingan dengan melakukan pendekatan kualitas untuk meningkatkan proses perangkat lunak dengan melakukan mapping antara ISO 9001:2000 dengan CMMI. Hal-hal yang dibahas berupa aspek-aspek dari standard ISO dan CMMI versi 1.1. Pada penelitian ini, dapat diperoleh strategi untuk menerapkan ISO 9001:2000 dan CMMI secara sinergi ketika merencanakan untuk melakukan peningkatan proses perangkat lunak. Selain itu

The Development of Bimodal Bilingualism: Implications for Linguistic Theory.

Science.gov (United States)

Lillo-Martin, Diane; de Quadros, Ronice Müller; Pichler, Deborah Chen

2016-01-01

A wide range of linguistic phenomena contribute to our understanding of the architecture of the human linguistic system. In this paper we present a proposal dubbed Language Synthesis to capture bilingual phenomena including code-switching and 'transfer' as automatic consequences of the addition of a second language, using basic concepts of Minimalism and Distributed Morphology. Bimodal bilinguals, who use a sign language and a spoken language, provide a new type of evidence regarding possible bilingual phenomena, namely code-blending, the simultaneous production of (aspects of) a message in both speech and sign. We argue that code-blending also follows naturally once a second articulatory interface is added to the model. Several different types of code-blending are discussed in connection to the predictions of the Synthesis model. Our primary data come from children developing as bimodal bilinguals, but our proposal is intended to capture a wide range of bilingual effects across any language pair.

Polyethyleneimine-loaded bimodal porous silica as low-cost and high-capacity sorbent for CO{sub 2} capture

Energy Technology Data Exchange (ETDEWEB)

Witoon, Thongthai, E-mail: fengttwi@ku.ac.th [National Center of Excellence for Petroleum, Petrochemicals and Advance Material, Department of Chemical Engineering, Faculty of Engineering, Kasetsart University, Bangkok 10900 (Thailand); Center for Advanced Studies in Nanotechnology and Its Applications in Chemical Food and Agricultural Industries, Kasetsart University, Bangkok 10900 (Thailand)

2012-11-15

In this work, bimodal (meso-macro) porous silicas with different mesopore diameters synthesized by using rice husk ash as a low-cost silica source and chitosan as a natural template were used as a polyethyleneimine (PEI) support for CO{sub 2} capture. Unimodal porous silica supports with equivalent mesopore diameters to bimodal porous silica supports have been prepared for purpose of comparison. Effects of different PEI contents (10, 20, 30, 40 and 50 wt%) on CO{sub 2} sorption capacity have been systematically investigated. The porous silica supports and the PEI-loaded porous silica supports were characterized by N{sub 2}-sorption analysis, scanning electron microscopy, Fourier transform infrared spectroscopy and thermal gravimetric analysis. CO{sub 2} sorption measurements of all PEI-loaded porous silica supports were performed at different adsorption temperatures (60, 75, 85, 90, 95 and 105 Degree-Sign C). At low PEI contents (10-20 wt%), the CO{sub 2} sorption of all adsorbents was found to decrease as a function of adsorption temperature, which was a characteristic of a thermodynamically-controlled regime. A transition from the thermodynamically-controlled regime to a kinetically-controlled regime was found when the PEI content was increased up to 30 wt% for PEI-loaded unimodal porous silicas and 40 wt% for PEI-loaded bimodal porous silicas. At high PEI contents (40-50 wt%), the CO{sub 2} capturing efficiency of the PEI-loaded bimodal porous silicas was found to be considerably greater than that of the PEI-loaded unimodal porous silicas, indicating that most of the amine groups of PEI molecules loaded on the unimodal porous silica supports was useless, and thus the appeared macroporosity of the bimodal porous silica supports could provide a higher effective amine density to adsorb CO{sub 2}. Highlights: Black-Right-Pointing-Pointer PEI-impregnated bimodal porous silica as low-cost sorbent for CO{sub 2} capture. Black-Right-Pointing-Pointer Macropores enhances

An introduction to information security and ISO27001:2013

CERN Document Server

Watkins, Steve

2013-01-01

Up to date with the latest version of the Standard (ISO27001:2013), An Introduction to information security and ISO27001:2013 is the perfect solution for anyone wanting an accurate, fast, easy-to-read primer on information security from an acknowledged expert on ISO27001.

Microstructure, plastic deformation and strengthening mechanisms of an Al–Mg–Si alloy with a bimodal grain structure

International Nuclear Information System (INIS)

Shakoori Oskooie, M.; Asgharzadeh, H.; Kim, H.S.

2015-01-01

Highlights: • Al6063 with bimodal grain structures was fabricated by a powder metallurgy route. • The bimodal alloys showed a reasonable ductility together with a high strength. • Grain boundary strengthening was reduced at higher fraction of coarse grains. • The enhanced tensile ductility was attributed to crack blunting and delamination. - Abstract: Al6063 alloys with bimodal grain size distributions comprised of ultrafine-grained (UFG) and coarse-grained (CG) regions were produced via mechanical milling followed by hot extrusion. High-energy planetary ball milling for 22.5 h with a rotational speed of 350 rpm was employed for the synthesis of nanocrystalline Al6063 powders. The as-milled Al6063 powders were mixed with 15, 30, and 45 vol.% of the unmilled powders and then the powder mixtures were consolidated via extrusion at 450 °C with an extrusion ratio of 9:1. The microstructure of the bimodal extrudates was investigated using optical microscope, transmission electron microscope (TEM) and field emission scanning electron microscope equipped with an electron backscattered diffraction (EBSD) detector. The deformation behavior was investigated by means of uniaxial tensile tests. The bimodal Al6063 exhibited balanced mechanical properties, including high yield stress and ultimate tensile strength resulting from the UFG regions together with reasonable ductility attained from the CG areas. The fracture surfaces demonstrated a ductile fracture mode, in which the dimple size was correlated with the grain structure. The strengthening mechanisms are discussed based on the dislocation models and the functions of the CGs in the deformation behavior and ductility enhancement of bimodal Al6063 are explored

Information security risk management for ISO27001/ISO27002

CERN Document Server

Calder, A; Watkins, S

2010-01-01

Drawing on international best practice, including ISO/IEC 27005, NIST SP800-30 and BS7799-3, the book explains in practical detail how to carry out an information security risk assessment. It covers key topics, such as risk scales, threats and vulnerabilities, selection of controls, and roles and responsibilities, and includes advice on choosing risk assessment software.

ISO 9001 2000 : the quality management process

CERN Document Server

Tricker, Ray

2006-01-01

With the publication of ISO 9001:2000, there is now a single quality management ?requirements? standard that is applicable to all organisations, products and services. ISO 9001:2000 is the only standard that can be used for the certification of a QMS and its generic requirements can be used by any organisation.ISO 9001:2000 applies to all types or organisations. It is the quality standard which specifies the requirements of quality management systems for use where organisations need to demonstrate their capability to provide products and services which meet both customer needs and relevant reg

[ISO 9001:2015 Certification in Quality Management].

Science.gov (United States)

Enders, Christian; Lang, Gabriele E; Lang, Gerhard K; Werner, Jens Ulrich

2017-07-01

Quality management improves the structures, processes and results of organizations of all kinds. Many practices and clinics have their existing quality management system certified according to ISO 9001, (e.g., to check their own quality management system or to obtain a testimonial against third parties). The latest version ISO 9001:2015 contains some changes, both structurally and in terms of content. These changes can be met with reasonable efforts. An ISO 9001:2015 certification represents a value for your organization, but these advantages are often not directly measurable. Georg Thieme Verlag KG Stuttgart · New York.

ISO 9001 and ISO 14001: An Integrated Quality Management System for an MTR Facility SAFARI-1 Research Reactor

International Nuclear Information System (INIS)

Du Bruyn, J.F.; Piani, C.S.B.

2005-01-01

The SAFARI-1 research reactor, owned and operated by the South African Nuclear Energy Corporation (Necsa), initially obtained ISO 9001 accreditation of its Quality, Health, Safety and Environmental (QHSE) management system via international affiliation from the South African Bureau of Standards (SABS) during 1998 and re-certification according to ISO 9001 (2000) in 2003. With ever-increasing demands on nuclear facilities to demonstrate conformance to environmental policies, SAFARI-1 has now developed an Environmental Management System (EMS) that is compliant with ISO 14001 (1996) and is fully integrated with the SAFARI-1 Quality Management System (QMS). The dynamic involvement of SAFARI-1 in commercial applications demanded that any transition of the original QMS to a fully incorporated QHSE system had to be done in a way that would ensure sustained delivery of a safe and reliable service with continuous quality. At the same time, the primary vision of operating a facility under an efficient financial management programme was essential. The criteria established by the original ISO 9001 compliant QMS were appraised against the additional requirements of ISO 14001 and a suitable superstructure derived for generation and implementation of an inclusive EMS. The transitional integration of this system was planned so as to produce a QMS suitable to quality, environmental and other management related issues for application to the unique function of a nuclear research reactor. (author)

Sertifikatõ ISO - mafioznaja struktura so znakom pljuss / Olesja Bõkova

Index Scriptorium Estoniae

Bõkova, Olesja

2005-01-01

Esimesed ISO sertifikaadid, mille aluseks on briti kvaliteedi standardite süsteem, anti Euroopa Liidus välja 1987. a. ISO sertifikaadid Eestis. Diagramm: Välja antud ISO 9000 sertifikaadid 1994-2004

Metrological management evaluation based on ISO10012: an empirical study in ISO-14001-certified Spanish companies

International Nuclear Information System (INIS)

Beltran, Jaime; Rivas, Miguel; Munuzuri, Jesus; Gonzalez, Cristina

2010-01-01

Environmental management systems based on the ISO 14001 standard rely strongly on metrological measurement and confirmation processes to certify the extent to which organizations monitor and improve their environmental behavior. Nevertheless, the literature lacks in studies that assess the influence of these metrological processes on the performance of environmental management in organizations, even now that the international standard ISO 10012 is already available to establish requisites and guidelines for the development of a metrological management system that is compatible with any other standardized management system. This work seeks to assess that influence through the development of an evaluation model for metrological management, which is then validated through an experimental analysis of the results obtained from the application of an audit process in 11 Spanish companies, all ISO-14001-certified and operating in different industrial sectors. (author)

Flexible transparent conducting films with embedded silver networks composed of bimodal-sized nanoparticles for heater application

Science.gov (United States)

Park, Ji Sun; Song, Yookyung; Park, Daseul; Kim, Yeon-Won; Kim, Yoon Jin

2018-06-01

A facile one-pot synthetic method for preparing the Ag nanoparticle inks with a bimodal size distribution was newly devised and they were successfully employed as a conducting filler to form the metal-mesh type transparent conducting electrodes on the flexible substrate. Bimodal-sized Ag nanoparticles were synthesized through the polyol process, and their size variation was occurred via finely tuned composition ratio between Ag+ ions and polymeric capping agents. The prepared bimodal-sized Ag nanoparticles exhibited the form of well-dispersed Ag nanoparticle inks without adding any dispersants and dispersion process. By filling the patterned micro-channels engraved on the flexible polymer substrate using a bimodal-sized Ag nanoparticle ink, a metal-mesh type transparent electrode (transmittance: 90% at 550 nm, haze: 1.5, area: 8 × 8 cm2) was fabricated. By applying DC voltage to the mesh type electrode, a flexible transparent joule heater was successfully achieved with a performance of 4.5 °C s‑1 heat-up rate at a low input power density.

Significance of ISO 9000 Quality Management System for ...

African Journals Online (AJOL)

Significance of ISO 9000 Quality Management System for Performance ... of ISO 9000 Quality Management System implementation for performance improvement. ... to find out the relationship between certification and process variability.

Neuroprotective effects of α-iso-cubebenol on glutamate-induced neurotoxicity.

Science.gov (United States)

Park, Sun Young; Choi, Yung Hyun; Park, Geuntae; Choi, Young-Whan

2015-09-01

α-Iso-cubebenol is a natural compound isolated from Schisandra chinensis, and is reported to have beneficial bioactivity including anti-inflammatory and anti-tumor activities. Glutamate-induced oxidative neuronal damage has been implicated in a variety of neurodegenerative disorders. Here we investigated the mechanisms of α-iso-cubebenol protection of mouse hippocampus-derived neuronal cells (HT22 cells) from apoptotic cell death induced by the major excitatory neurotransmitter, glutamate. Pretreatment with α-iso-cubebenol markedly attenuated glutamate-induced loss of cell viability and release of lactate dehydrogenase), in a dose-dependent manner. α-Iso-cubebenol significantly reduced glutamate-induced intracellular reactive oxygen species and calcium accumulation. Strikingly, α-iso-cubebenol inhibited glutamate-induced mitochondrial depolarization, which releases apoptosis-inducing factor from mitochondria. α-Iso-cubebenol also suppressed glutamate-induced phosphorylation of extracellular-signal-regulated kinases. Furthermore, α-iso-cubebenol induced CREB phosphorylation and Nrf-2 nuclear accumulation and increased the promoter activity of ARE and CREB in HT22 cells. α-Iso-cubebenol also upregulated the expression of phase-II detoxifying/antioxidant enzymes such as HO-1 and NQO1. Subsequent studies revealed that the inhibitory effects of α-iso-cubebenol on glutamate-induced apoptosis were abolished by small interfering RNA-mediated knockdown of CREB and Nrf-2. These findings suggest that α-iso-cubebenol prevents excitotoxin-induced oxidative damage to neurons by inhibiting apoptotic cell death, and might be a potential preventive or therapeutic agent for neurodegenerative disorders. Copyright © 2015 Elsevier B.V. All rights reserved.

SISTEM HACCP KE DALAM SISTEM MANAJEMEN KEAMANAN PANGAN ISO 22000:2009 (STUDI KASUS DI PT INDOKOM SAMUDRA PERSADA [The Merger of Quality Assurance System ISO 9001:2008 and HACCP system into Food Safety Management SystemISO 22000:2009 (Case Study at Indoko

Directory of Open Access Journals (Sweden)

Novri Ilmiawan

2014-12-01

Full Text Available The object of this research was to merge the application of HACCP system and ISO 9001:2008 in ISP company into ISO 22000:2009. The  research method used was case study method. The study was conducted on three stages. The first was the arrangement gap analysis conducted by comparing the conditions of the company with ISO 22000:2009 standards. The second was by observing sanitation and pre requisite programs. The third was by observing traceability system. The data in this research were reported descriptively, consisted of ISO 9001:2008 and HACCP application in the company and the gaps of principles in ISO 22000:2009 toward ISO 9001:2008 and HACCP. The result showed that ISP company has applied 12 steps which covered in HACCP system, and also the ISO 9001 system were appropriate with ISO 9001:2008 standards in every clauses. Pre requisite program (GMP and SSOP have been effectively applied. GMP in ISP company is categorized on the first spot (excellent. The eight keys of SSOP have been fulfilled. ISP company has been fulfilling 54 from 57 (94.74% criteria in ISO 22000:2009 standards, yet there still several things needed to be improved, which are the quality manual content  and HACCP table plan and its monitoring. The  traceability system has been applied well in ISP .   Key words : HACCP, ISO 9001, ISO 22000, GMP, SSOP.

Does bimodal stimulus presentation increase ERP components usable in BCIs?

NARCIS (Netherlands)

Thurlings, M.E.; Brouwer, A.M.; Erp, J.B.F. van; Blankertz, B.; Werkhoven, P.J.

2012-01-01

Event-related potential (ERP)-based brain–computer interfaces (BCIs) employ differences in brain responses to attended and ignored stimuli. Typically, visual stimuli are used. Tactile stimuli have recently been suggested as a gaze-independent alternative. Bimodal stimuli could evoke additional brain

[Accreditation of clinical laboratories based on ISO standards].

Science.gov (United States)

Kawai, Tadashi

2004-11-01

International Organization for Standardization (ISO) have published two international standards (IS) to be used for accreditation of clinical laboratories; ISO/IEC 17025:1999 and ISO 15189:2003. Any laboratory accreditation body must satisfy the requirements stated in ISO/IEC Guide 58. In order to maintain the quality of the laboratory accreditation bodies worldwide, the International Laboratory Accreditation Cooperation (ILAC) has established the mutual recognition arrangement (MRA). In Japan, the International Accreditation Japan (IAJapan) and the Japan Accreditation Board for Conformity Assessment (JAB) are the members of the ILAC/MRA group. In 2003, the Japanese Committee for Clinical Laboratory Standards (JCCLS) and the JAB have established the Development Committee of Clinical Laboratory Accreditation Program (CLAP), in order to establish the CLAP, probably starting in 2005.

A bimodal flexible distribution for lifetime data

OpenAIRE

Ramires, Thiago G.; Ortega, Edwin M. M.; Cordeiro, Gauss M.; Hens, Niel

2016-01-01

A four-parameter extended bimodal lifetime model called the exponentiated log-sinh Cauchy distribution is proposed. It extends the log-sinh Cauchy and folded Cauchy distributions. We derive some of its mathematical properties including explicit expressions for the ordinary moments and generating and quantile functions. The method of maximum likelihood is used to estimate the model parameters. We implement the fit of the model in the GAMLSS package and provide the codes. The flexibility of the...

Environmental Management System ISO 14001

CERN Document Server

Haider, Syed

2010-01-01

This is a must-have tool for any company in the process of adopting and incorporating the ISO 14001:2004 requirements, this book and accompanying CD-ROM provides the latest updates and amendments and translates the ISO language into actionable strategy. Offering administrative solutions to managers of all sorts, it includes practical examples of policies with objectives, targets, and action plans applicable to any process related industry or an ordinary organization. With template formats and hands-on flow charts to describe step-by-step system development, documentation, and implementation ph

Synthesis and Biological Activity of 2',3'-iso-Aryl-abscisic Acid Analogs.

Science.gov (United States)

Wan, Chuan; Wang, Mingan; Yang, Dongyan; Han, Xiaoqiang; Che, Chuanliang; Ding, Shanshan; Xiao, Yumei; Qin, Zhaohai

2017-12-15

2',3'- iso -Benzoabscisic acid ( iso -PhABA), an excellent selective abscisic acid (ABA) analog, was developed in our previous work. In order to find its more structure-activity information, some structural modifications were completed in this paper, including the substitution of phenyl ring and replacing the ring with heterocycles. Thus, 16 novel analogs of iso -PhABA were synthesized and screened with three bioassays, Arabidopsis and lettuce seed germination and rice seedling elongation. Some of them, i.e., 2',3'- iso -pyridoabscisic acid ( iso -PyABA) and 2',3'- iso -franoabscisic acid ( iso -FrABA), displayed good bioactivities that closed to iso -PhABA and natural (+)-ABA. Some others, for instance, substituted- iso -PhABA, exhibited certain selectivity to different physiological process when compared to iso -PhABA or (+)-ABA. These analogs not only provided new candidates of ABA-like synthetic plant growth regulators (PGRs) for practical application, but also new potential selective agonist/antagonist for probing the specific function of ABA receptors.

Stellar Rotation with Kepler and Gaia: Evidence for a Bimodal Star Formation History

Science.gov (United States)

Davenport, James

2018-01-01

Kepler stars with rotation periods measured via starspot modulations in their light curves have been matched against the astrometric data from Gaia Data Release 1. A total of 1,299 bright rotating stars were recovered, most with temperatures hotter than 5000 K. From these, 894 were selected as being near the main sequence. These main sequence stars show a bimodality in their rotation period distribution, centered around a ~600 Myr rotation-isochrone. This feature matches the bimodal period distribution found in cooler stars with Kepler, but was previously undetected for solar-type stars due to sample contamination by subgiant and binary stars. A tenuous connection between the rotation period and total proper motion is found, suggesting the period bimodality is due to the age distribution of stars within 300pc of the Sun, rather than a phase of rapid angular momentum loss. I will discuss how the combination of Kepler/K2/TESS with Gaia will enable us to map the star formation history of our galactic neighborhood.

Information security in accordance with ISO/IEC 27000

OpenAIRE

Košćak , Damjan

2011-01-01

The diploma assignment discusses Information Technology Security according to standards ISO/IEC 27001 and ISO/IEC 27002. Diploma consists of two parts. In the first part of the diploma a theoretical bases of information security are presented. The second part presents the introduction of ISO/IEC 27001 security standard in the company »X« in wich I performed a practical training. In the closure my diploma work is upgraded with results of my research work and their analysis as well as wit...

The role of continuous low-frequency harmonicity cues for interrupted speech perception in bimodal hearing.

Science.gov (United States)

Oh, Soo Hee; Donaldson, Gail S; Kong, Ying-Yee

2016-04-01

Low-frequency acoustic cues have been shown to enhance speech perception by cochlear-implant users, particularly when target speech occurs in a competing background. The present study examined the extent to which a continuous representation of low-frequency harmonicity cues contributes to bimodal benefit in simulated bimodal listeners. Experiment 1 examined the benefit of restoring a continuous temporal envelope to the low-frequency ear while the vocoder ear received a temporally interrupted stimulus. Experiment 2 examined the effect of providing continuous harmonicity cues in the low-frequency ear as compared to restoring a continuous temporal envelope in the vocoder ear. Findings indicate that bimodal benefit for temporally interrupted speech increases when continuity is restored to either or both ears. The primary benefit appears to stem from the continuous temporal envelope in the low-frequency region providing additional phonetic cues related to manner and F1 frequency; a secondary contribution is provided by low-frequency harmonicity cues when a continuous representation of the temporal envelope is present in the low-frequency, or both ears. The continuous temporal envelope and harmonicity cues of low-frequency speech are thought to support bimodal benefit by facilitating identification of word and syllable boundaries, and by restoring partial phonetic cues that occur during gaps in the temporally interrupted stimulus.

ISO sertifikaat kuulutab tootja mainet üle maailma / Ain Alvela

Index Scriptorium Estoniae

Alvela, Ain, 1967-

2006-01-01

Ilmunud ka: Delovõje Vedomosti 12. apr. lk. 24-25. ISO standardi rakendamine tagab toodangu kvaliteedi ja annab firmale usaldusväärsuse. Kommenteerib Ain Noormägi. Vt. samas: ISO 9001; ISO 14 001; Universaalne standard kohandub ettevõtte vajadustega

A bimodal power and propulsion system based on cermet fuel and heat pipe energy transport

International Nuclear Information System (INIS)

Polansky, G.F.; Gunther, N.A.; Rochow, R.F.; Bixler, C.H.

1995-01-01

Bimodal space reactor systems provide both thermal propulsion for the spacecraft orbital transfer and electrical power to the spacecraft bus once it is on station. These systems have the potential to increase both the available payload in high energy orbits and the available power to that payload. These increased mass and power capabilities can be used to either reduce mission cost by permitting the use of smaller launch vehicles or to provide increased mission performance from the current launch vehicle. A major barrier to the deployment of these bimodal systems has been the cost associated with their development. This paper describes a bimodal reactor system with performance potential to permit more than 70% of the instrumented payload of the Titan IV/Centaur to be launched from the Atlas IIAS. The development cost is minimized by basing the design on existing component technologies

TRACING OUTFLOWS AND ACCRETION: A BIMODAL AZIMUTHAL DEPENDENCE OF Mg II ABSORPTION

Energy Technology Data Exchange (ETDEWEB)

Kacprzak, Glenn G. [Swinburne University of Technology, Victoria 3122 (Australia); Churchill, Christopher W.; Nielsen, Nikole M., E-mail: gkacprzak@astro.swin.edu.au [New Mexico State University, Las Cruces, NM 88003 (United States)

2012-11-20

We report a bimodality in the azimuthal angle distribution of gas around galaxies as traced by Mg II absorption: halo gas prefers to exist near the projected galaxy major and minor axes. The bimodality is demonstrated by computing the mean azimuthal angle probability distribution function using 88 spectroscopically confirmed Mg II-absorption-selected galaxies [W{sub r} (2796) {>=} 0.1 A] and 35 spectroscopically confirmed non-absorbing galaxies [W{sub r} (2796) < 0.1 A] imaged with Hubble Space Telescope and Sloan Digital Sky Survey. The azimuthal angle distribution for non-absorbers is flat, indicating no azimuthal preference for gas characterized by W{sub r} (2796) < 0.1 A. We find that blue star-forming galaxies clearly drive the bimodality while red passive galaxies may exhibit an excess along their major axis. These results are consistent with galaxy evolution scenarios where star-forming galaxies accrete new gas, forming new stars and producing winds, while red galaxies exist passively due to reduced gas reservoirs. We further compute an azimuthal angle dependent Mg II absorption covering fraction, which is enhanced by as much as 20%-30% along the major and minor axes. The W{sub r} (2796) distribution for gas along the major axis is likely skewed toward weaker Mg II absorption than for gas along the projected minor axis. These combined results are highly suggestive that the bimodality is driven by gas accreted along the galaxy major axis and outflowing along the galaxy minor axis. Adopting these assumptions, we find that the opening angle of outflows and inflows to be 100 Degree-Sign and 40 Degree-Sign , respectively. We find that the probability of detecting outflows is {approx}60%, implying that winds are more commonly observed.

SWIFT GRB GRB071010B: OUTLIER OF THE E srcpeak - E γ AND E iso - E srcpeak - t srcjet CORRELATIONS

International Nuclear Information System (INIS)

Urata, Yuji; Lee, Induk; Ip, Wing Huen; Huang, Kuiyun; Im, Myungshin; Deng Jinsong; Liping Xin; Qiu Yulei; Wei Jianyan; Zheng Weikang; Krimm, Hans; Ohno, Masanori; Sugita, Satoshi; Tashiro, Makoto; Yamaoka, Kazutaka

2009-01-01

We present multi-band results for GRB071010B based on Swift, Suzaku, and ground-based optical observations. This burst is an ideal target to evaluate the robustness of the E src peak - E iso and E src peak - E γ relations, whose studies have been in stagnation due to the lack of the combined estimation of E src peak and long-term optical monitoring. The joint prompt spectral fitting using Swift/Burst Alert Telescope and Suzaku/Wide-band All-sky Monitor data yielded the spectral peak energy as E src peak of 86.5 +6.4 -6.3 keV and E iso of 2.25 +0.19 -0.16 x 10 52 erg with z = 0.947. The optical afterglow light curve is well fitted by a simple power law with temporal index α = -0.60 ± 0.02. The lower limit of temporal break in the optical light curve is 9.8 days. Our multi-wavelength analysis reveals that GRB071010B follows E src peak - E iso but violates the E src peak - E γ and E iso - E src peak - t src jet at more than the 3σ level.

Antioxidant mechanisms of iso-6-cassine in suppressing seizures induced by pilocarpine

Directory of Open Access Journals (Sweden)

Rivelilson Mendes de Freitas

2011-06-01

Full Text Available The aim of this study was to evaluate the in vitro antioxidant effects of 12-[(2R,5R,6R-5-hydroxy-6-methylpiperidin-2-yl]dodecan-2-one (iso-6-cassine; ISO and the anticonvulsant effects of ISO on pilocarpine-induced seizures in rats. Wistar rats were treated with 0.9% saline (i.p., control group, pilocarpine (400 mg/kg, i.p., pilocarpine group, and the association of ISO (1.0 mg/kg, i.p. plus pilocarpine (400 mg/kg, i.p., 30 min after administration of ISO (ISO plus pilocarpine group. After the treatments all groups were observed for 1h. The antioxidant effect of ISO on the pilocarpine model was assessed by determining the activity of glutathione peroxidase (GPx, glutathione-S-transferase (GST and catalase (CAT as well as the levels of reactive species (RS and lipid peroxidation (LP. In vitro, ISO (5 μM reduced RS and LP. ISO (1.0 mg/kg and abolished seizures and death induced by pilocarpine in rats. ISO protected against the increase in the RS and LP levels, GST activity as well as the inhibition of GPx activity caused by pilocarpine. In addition, ISO increased the catalase activity in hippocampus of seized rats. In conclusion, the dta suggest that ISO can present anticonvulsant and antioxidant properties in the pilocarpine model of seizures in rats.

ISO developments in the United States

International Nuclear Information System (INIS)

Hogan, William W.

1998-01-01

An important feature of the restructuring process in the United States is the creation of independent system operators (ISOs) to coordinate dispatch and access to transmission grids. A number of ISOs have been proposed and are summarized here. Perhaps the greatest challenge is the pricing of transmission to give proper economic signals to market participants, and the locational pricing scheme now operating in the PJM system offers the best hope for efficient pricing. (author)

Emotional Intensity Modulates the Integration of Bimodal Angry Expressions: ERP Evidence

Directory of Open Access Journals (Sweden)

Zhihui Pan

2017-06-01

Full Text Available Integration of information from face and voice plays a central role in social interactions. The present study investigated the modulation of emotional intensity on the integration of facial-vocal emotional cues by recording EEG for participants while they were performing emotion identification task on facial, vocal, and bimodal angry expressions varying in emotional intensity. Behavioral results showed the rates of anger and reaction speed increased as emotional intensity across modalities. Critically, the P2 amplitudes were larger for bimodal expressions than for the sum of facial and vocal expressions for low emotional intensity stimuli, but not for middle and high emotional intensity stimuli. These findings suggested that emotional intensity modulates the integration of facial-vocal angry expressions, following the principle of Inverse Effectiveness (IE in multimodal sensory integration.

Matching Automatic Gain Control Across Devices in Bimodal Cochlear Implant Users.

Science.gov (United States)

Veugen, Lidwien C E; Chalupper, Josef; Snik, Ad F M; Opstal, A John van; Mens, Lucas H M

2016-01-01

The purpose of this study was to improve bimodal benefit in listeners using a cochlear implant (CI) and a hearing aid (HA) in contralateral ears, by matching the time constants and the number of compression channels of the automatic gain control (AGC) of the HA to the CI. Equivalent AGC was hypothesized to support a balanced loudness for dynamically changing signals like speech and improve bimodal benefit for speech understanding in quiet and with noise presented from the side(s) at 90 degree. Fifteen subjects participated in the study, all using the same Advanced Bionics Harmony CI processor and HA (Phonak Naida S IX UP). In a 3-visit crossover design with 4 weeks between sessions, performance was measured using a HA with a standard AGC (syllabic multichannel compression with 1 ms attack time and 50 ms release time) or an AGC that was adjusted to match that of the CI processor (dual AGC broadband compression, 3 and 240 msec attack time, 80 and 1500 msec release time). In all devices, the AGC was activated above the threshold of 63 dB SPL. The authors balanced loudness across the devices for soft and loud input sounds in 3 frequency bands (0 to 548, 548 to 1000, and >1000 Hz). Speech understanding was tested in free field in quiet and in noise for three spatial speaker configurations, with target speech always presented from the front. Single-talker noise was either presented from the CI side or the HA side, or uncorrelated stationary speech-weighted noise or single-talker noise was presented from both sides. Questionnaires were administered to assess differences in perception between the two bimodal fittings. Significant bimodal benefit over the CI alone was only found for the AGC-matched HA for the speech tests with single-talker noise. Compared with the standard HA, matched AGC characteristics significantly improved speech understanding in single-talker noise by 1.9 dB when noise was presented from the HA side. AGC matching increased bimodal benefit

ISO 9001 in a neonatal intensive care unit (NICU).

Science.gov (United States)

Vitner, Gad; Nadir, Erez; Feldman, Michael; Yurman, Shmuel

2011-01-01

The aim of this paper is to present the process for approving and certifying a neonatal intensive care unit to ISO 9001 standards. The process started with the department head's decision to improve services quality before deciding to achieve ISO 9001 certification. Department processes were mapped and quality management mechanisms were developed. Process control and performance measurements were defined and implemented to monitor the daily work. A service satisfaction review was conducted to get feedback from families. In total, 28 processes and related work instructions were defined. Process yields showed service improvements. Family satisfaction improved. The paper is based on preparing only one neonatal intensive care unit to the ISO 9001 standard. The case study should act as an incentive for hospital managers aiming to improve service quality based on the ISO 9001 standard. ISO 9001 is becoming a recommended tool to improve clinical service quality.

Exploratory Research of ISO 14001:2015 Transition among Portuguese Organizations

Directory of Open Access Journals (Sweden)

Luis Miguel Fonseca

2018-03-01

Full Text Available The purpose of this paper is the assessment of the ISO 14001:2015 transition process among Portuguese ISO 14001 certified organizations, including those that successfully have already achieved ISO 14001:2015 certification. A considerable number of the surveyed companies proceeded with the transition to the ISO 14001:2015 by introducing slight adjustments and were supported by external consultants. Nearly all of the respondent companies (97% intend to transition until 15th September 2018. The highest ranked reported benefit is the “integrated approach with other management sub-systems” with a well-consolidated perception from the surveyed companies. This is aligned with the ISO 14001:2015 goal of improving the compatibility of management standards supported on the Annex SL. “Alignment with business strategy”, “improved top management commitment” and “improved internal and external communication” are also perceived to obtain significant benefits from ISO 14001:2015. The statistical tests carried out (Kruskal–Wallis confirmed that the perception of some achieved ISO 14001:2015 certification benefits is dependent on the size of the organization. Concerning the motivations to proceed with certification, results suggest that there is not a particular company profile that is compelled to certify their EMS based on a specific type of motivation (Internal or External. Due to ISO 14001:2015 novelty, these exploratory results should be subjected to additional research confirmation.

Boiling Patterns of Iso-asymmetric Nuclear Matter

International Nuclear Information System (INIS)

Tõke, Jan

2013-01-01

Limits of thermodynamic metastability of self-bound neutron-rich nuclear matter are explored within the framework of microcanonical thermodynamics of interacting Fermi Gas model in Thomas-Fermi approximation. It is found that as the excitation energy per nucleon of the system is increased beyond a certain limiting value, the system loses metastability and becomes unstable with respect to joint fluctuations in excitation energy per nucleon and in isospin per nucleon. As a result, part of the system is forced to boil off in a form of iso-rich non-equilibrated vapors. Left behind in such a process, identifiable with distillation, is a more iso-symmetric metastable residue at a temperature characteristic of its residual isospin content. With a progressing increase in the initial excitation energy per nucleon, more neutron-rich matter is boiled off and a more iso-symmetric residue is left behind with progressively increasing characteristic temperature. Eventually, when all excess neutrons are shed, the system boils uniformly with a further supply of excitation energy, leaving behind a smaller and smaller residue at a characteristic boiling-point temperature of iso-symmetric matter.

PRAPI: post-transcriptional regulation analysis pipeline for Iso-Seq.

Science.gov (United States)

Gao, Yubang; Wang, Huiyuan; Zhang, Hangxiao; Wang, Yongsheng; Chen, Jinfeng; Gu, Lianfeng

2018-05-01

The single-molecule real-time (SMRT) isoform sequencing (Iso-Seq) based on Pacific Bioscience (PacBio) platform has received increasing attention for its ability to explore full-length isoforms. Thus, comprehensive tools for Iso-Seq bioinformatics analysis are extremely useful. Here, we present a one-stop solution for Iso-Seq analysis, called PRAPI to analyze alternative transcription initiation (ATI), alternative splicing (AS), alternative cleavage and polyadenylation (APA), natural antisense transcripts (NAT), and circular RNAs (circRNAs) comprehensively. PRAPI is capable of combining Iso-Seq full-length isoforms with short read data, such as RNA-Seq or polyadenylation site sequencing (PAS-seq) for differential expression analysis of NAT, AS, APA and circRNAs. Furthermore, PRAPI can annotate new genes and correct mis-annotated genes when gene annotation is available. Finally, PRAPI generates high-quality vector graphics to visualize and highlight the Iso-Seq results. The Dockerfile of PRAPI is available at http://www.bioinfor.org/tool/PRAPI. lfgu@fafu.edu.cn.

Galex Lyman-alpha Emitters: Physical Properties, Luminosity Bimodality, And Morphologies.

Science.gov (United States)

Mallery, Ryan P.

2010-01-01

The Galaxy Evolution Explorer spectroscopic survey has uncovered a large statistically significant sample of Lyman-alpha emitters at z sim0.3. ACS imaging of these sources in the COSMOS and AEGIS deep fields reveals that these Lyman-alpha emitters consist of two distinct galaxy morphologies, face on spiral galaxies and compact starburst/merging systems. The morphology bimodality also results in a bimodal distribution of optical luminosity. A comparison between the UV photometry and MIPS 24 micron detections of these sources indicates that they are bluer, and have less dust extinction than similar star forming galaxies that lack Lyman-alpha detection. Our findings show how the global gas and dust distribution of star forming galaxies inhibits Lyman-alpha emission in star forming galaxies. GALEX is a NASA Small Explorer, launched in April 2003. We gratefully acknowledge NASA's support for construction, operation, and science analysis for the GALEX mission, developed in cooperation with the CNES of France and the Korean Ministry of Science and Technology.

ISO's analysis of Comet Hale-Bopp

Science.gov (United States)

1997-03-01

The European Space Agency's Infrared Space Observatory ISO inspected Comet Hall-Bopp during the spring and autumn of 1996. The need to keep ISO's telescope extremely cold restricts the spacecraft's pointing in relation to the Sun and the Earth and it ruled out observations at other times. The analyses of the 1996 observations are not yet complete, but already they give new insight into the nature of comets. Comet Hale-Bopp is believed to be a large comet with a nucleus up to 40 kilometres wide. It was discovered in July 1995 by two American astronomers working independently, Alan Hale and Thomas Bopp. At that time, the comet was a billion kilometres away from the Sun, but 200 times brighter than Halley's Comet was, when at a comparable distance. Comet Hale-Bopp will make its closest approach to the Earth on 22 March, and its closest approach to the Sun (perihelion) on 1 April 1997. Some scientific results from ISO The discovery of Comet Hale-Bopp occurred before ISO's launch in November 1995. When first observed by ISO in March and April 1996, the comet was still 700 million kilometres from the Sun, and almost as far from the Earth and ISO. With its privileged view of infrared wavebands inaccessible from the Earth's surface, ISO's photometer ISOPHOT discovered that carbon dioxide was an important constituent of the comet's emissions of vapour.ISOPHOT measured the temperature of the dust cloud around Comet Hale-Bopp. In March 1996, when the comet was still more than 700 million kilometres from the Sun, the dust cloud was at minus 120 degrees C. When ISOPHOT made similar observations in October 1996, the comet was 420 million kilometres from the Sun, and the dust cloud had warmed to about minus 50 degrees C. Intensive observations of Comet Hale-Bopp were also made by ISO's Short-Wave Spectrometer SWS, the Long-Wave Spectrometer LWS, and the ISOPHOT spectrometer PHOT-S. Results are due for publication at the end of March. They will give details about the composition

CNEN, IAEA and ISO normative requirements for measurement management

International Nuclear Information System (INIS)

Kibrit, Eduardo

2009-01-01

International standard ISO 10012:2003 establishes requirements for measurement management systems, including requirements for measurement processes and measuring equipment. ISO 9001:2008 presents requirements for quality management systems, including requirements for the control of monitoring and measuring equipment. ISO 17025:2005 presents general requirements for the competence of testing and calibration laboratories. In the nuclear field the requirements for measurement management are established by standards published by the International Atomic Energy Agency (IAEA), and in Brazil, by the National Nuclear Energy Commission (CNEN). The present paper presents and discusses the normative requirements for measurement management, considering requirements established by National Nuclear Energy Commission (CNEN), International Atomic Energy Agency (IAEA), and International Organisation for Standardisation (ISO). (author)

Die bestuur en opleiding van SABS ISO 9000 reeks

OpenAIRE

2014-01-01

With the lifting of sanctions, South African businesses are faced with a new challenge to compete against their international counterparts on the international and domestic markets. Competing on the international markets is dependant on conforming to a recognised quality management system standard such as ISO 9000 (ISO International Standards Organisation). The South African equivalent for this standard is SABS ISO 9000. (SABS - South African Bureau of Standards). It is thus important for Sou...

Application of ISO 9001:2000 in a Nuclear Medicine Department

International Nuclear Information System (INIS)

Rayo, J.I.; Serrano, J.; Martin, R.; Corral, C.

2002-01-01

Since 1947 ISO has been developing voluntary technical standards over almost all sectors of business, industry, and technology. The ISO 9000 standards were published in 1987, and new versions of the standards saw daylight in 1994 and 2000. The highlights of ISO 9001:2000 are: quality management system, management responsibility, resource management, product realization and measurement, analysis and improvement. Aim: Application of ISO 9001:2000 to a Nuclear Medicine Department for provides the organization with a model to follow, customer focus, people will understand the goals of the organization and are motivated to work for objectives and lower costs and shorter cycle times through effective use of resources. Conclusion: ISO 9001:2000 focuses on continual improvement of business processes that should be a permanent objective of the Nuclear Medicine Department

Gloss uniformity measurement update for ISO/IEC 19751

Science.gov (United States)

Ng, Yee S.; Cui, Chengwu; Kuo, Chunghui; Maggard, Eric; Mashtare, Dale; Morris, Peter

2005-01-01

To address the standardization issues of perceptually based image quality for printing systems, ISO/IEC JTC1/SC28, the standardization committee for office equipment chartered the W1.1 project with the responsibility of drafting a proposal for an international standard for the evaluation of printed image quality1. An ISO draft Standard2, ISO/WD 19751-1, Office Equipment - Appearance-based image quality standards for printers - Part 1: Overview, Procedure and Common Methods, 2004 describes the overview of this multi-part appearance-based image quality standard. One of the ISO 19751 multi-part Standard"s tasks is to address the appearance-based gloss and gloss uniformity issues (in ISO 19751-2). This paper summarizes the current status and technical progress since the last two updates3, 4. In particular, we will be discussion our attempt to include 75 degree gloss (G75) objective measurement5 in differential gloss and within-page gloss uniformity. The result for a round-robin experiment involving objective measurement of differential gloss using G60 and G75 gloss measurement geometry is described. The results for two perceptual-based round-robin experiments relating to haze effect on the perception of gloss, and gloss artifacts (gloss streaks/bands, gloss graininess/mottle) are discussed.

The Relationship between the Training Function and ISO-9000 Registration.

Science.gov (United States)

Maxwell, Randy C.; Jost, Karen L.

ISO 9000 is one of a series of international standards providing guidelines and governing quality of products and services. The ISO 9000 certification demonstrates the capability of a supplier to control the processes that determine the acceptability of the product or service being supplied. This paper focuses on the training aspects of ISO 9000…

API and ISO standards can be combined

International Nuclear Information System (INIS)

Weightman, R.T.; Warnack, M.F.

1992-01-01

This paper reports that oil field equipment and product manufacturers can maintain a competitive advantage and minimize costs by integrating American Petroleum Institute (API) licensing programs with International Standards Organization (ISO) 9001 standards under one quality system. A combined quality system approach can position a company for quality system certification under ISO 9001 while maintaining API specifications. Furthermore, only one quality system manual is needed for API licensing and ISO certification, avoiding duplication of effort. The benefits of a documented quality program include the flowing: Job descriptions and personnel qualification requirements are documented; The improved documentation allows direct tracing of specific production activities; Laboratory test methods and calibration of test equipment follow accepted standards for more reliable and reproducible test data; Quality control becomes proactive, not reactive, through internal process controls previously not implemented; Employee attitudes improve through appreciation for the overall goals of the company; Ambiguous quality issues, such as documenting special customer requirements, are easily resolved; and The company image improves with customers, particularly for those that require API Specification Q1 or ISO 9001 compliance or those having their own quality performance standards

Bimodal Networks as Candidates for Electroactive Polymers

DEFF Research Database (Denmark)

Bahrt, Frederikke; Daugaard, Anders Egede; Bejenariu, Anca Gabriela

An alternative network formulation method was adopted in order to obtain a different type of silicone based elastomeric systems - the so-called bimodal networks - using two vinyl-terminated polydimethyl siloxanes (PDMS) of different molecular weight, a labelled crosslinker (3 or 4-functional), an...... themselves between the long chains and show how this leads to unexpectedly good properties for DEAP purposes due both to the low extensibility of the short chains that attach strongly the long chains and to the extensibility of the last ones that retards the rupture process....

Experience with ISO quality control in assisted reproductive technology.

Science.gov (United States)

Alper, Michael M

2013-12-01

Assisted reproductive technology (ART) programs are complex organizations requiring the integration of multiple disciplines. ISO 9001:2008 is a quality management system that is readily adaptable to an ART program. The value that ISO brings to the entire organization includes control of documents, clear delineation of responsibilities of staff members, documentation of the numerous processes and procedures, improvement in tracking and reducing errors, and overall better control of systems. A quality ART program sets quality objectives and monitors their progress. ISO provides a sense of transparency within the organization and clearer understanding of how service is provided to patients. Most importantly, ISO provides the framework to allow for continual improvement. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Controllability of a Class of Bimodal Discrete-Time Piecewise Linear Systems

NARCIS (Netherlands)

Yurtseven, E.; Camlibel, M.K.; Heemels, W.P.M.H.

2013-01-01

In this paper we will provide algebraic necessary and sufficient conditions for the controllability/reachability/null controllability of a class of bimodal discrete-time piecewise linear systems including several instances of interest that are not covered by existing works which focus primarily on

On the composition of ISO 25964 hierarchical relations (BTG, BTP, BTI)

NARCIS (Netherlands)

Alexiev, A; Isaac, A.H.J.C.A.; Lindenthal, J

2015-01-01

Knowledge organization systems (KOS) can use different types of hierarchical relations: broader generic (BTG), broader partitive (BTP), and broader instantial (BTI). The latest ISO standard on thesauri (ISO 25964) has formalized these relations in a corresponding OWL ontology (De Smedt et al., ISO

ISO 14000 information platform. Quarterly report, January 1--March 31, 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

GETE, through its ISO 14000 Information Platform, globeNet{trademark} (www.iso14000.net), seeks to provide FETC and the US Department of Energy (DOE) with a timely, accurate, and reliable information resource on the issue of environmental management standards. This resource allows FETC to keep track of the latest developments in the ISO 14000 arena, in DOE as well as throughout the federal complex and industry. Utilizing this information, FETC and DOE can make critical decisions on their own use and implementation of the ISO 14000 standards. The information platform also provides FETC with a forum to present information on its activities, such as the DOE ISO 14000 Pilot Projects, and as an information gathering and dissemination resource for its publications. GETE works with an array of national and international contacts and content sources to gather information and provide daily updates on ISO 14000 and related environmental management issues.

Transient bimodality in interacting particle systems

International Nuclear Information System (INIS)

Calderoni, P.; Pellegrinotti, A.; Presutti, E.; Vares, M.E.

1989-01-01

The authors consider a system of spins which have values ± 1 and evolve according to a jump Markov process whose generator is the sum of two generators, one describing a spin-flip Glauber process, the other a Kawasaki (stirring) evolution. It was proven elsewhere that if the Kawasaki dynamics is speeded up by a factor var-epsilon -2 , then, in the limit var-epsilon → 0 (continuum limit), propagation of chaos holds and the local magnetization solves a reaction-diffusion equation. They choose the parameters of the Glauber interaction so that the potential of the reaction term in the reaction-diffusion equation is a double-well potential with quartic maximum at the origin. They assume further that for each var-epsilon the system is in a finite interval of Z with var-epsilon -1 sites and periodic boundary conditions. They specify the initial measure as the product measure with 0 spin average, thus obtaining, in the continuum limit, a constant magnetic profile equal to 0, which is a stationary unstable solution to the reaction-diffusion equation. They prove that at times of the order var-epsilon -1/2 propagation of chaos does not hold any more and, in the limit as var-epsilon → 0, the state becomes a nontrivial superposition of Bernoulli measures with parameters corresponding to the minima of the reaction potential. The coefficients of such a superposition depend on time (on the scale var-epsilon -1/2 ) and at large times (on this scale) the coefficient of the term corresponding to the initial magnetization vanishes (transient bimodality). This differs from what was observed by De Masi, Presutti, and Vares, who considered a reaction potential with quadratic maximum and no bimodal effect was seen, as predicted by Broggi, Lugiato, and Colombo

Significant Corrosion Resistance in an Ultrafine-Grained Al6063 Alloy with a Bimodal Grain-Size Distribution through a Self-Anodic Protection Mechanism

Directory of Open Access Journals (Sweden)

Mahdieh Shakoori Oskooie

2016-12-01

Full Text Available The bimodal microstructures of Al6063 consisting of 15, 30, and 45 vol. % coarse-grained (CG bands within the ultrafine-grained (UFG matrix were synthesized via blending of high-energy mechanically milled powders with unmilled powders followed by hot powder extrusion. The corrosion behavior of the bimodal specimens was assessed by means of polarization, steady-state cyclic polarization and impedance tests, whereas their microstructural features and corrosion products were examined using optical microscopy (OM, scanning transmission electron microscopy (STEM, field emission scanning electron microscopy (FE-SEM, electron backscattered diffraction (EBSD, energy dispersive spectroscopy (EDS, and X-ray diffraction (XRD techniques. The bimodal Al6063 containing 15 vol. % CG phase exhibits the highest corrosion resistance among the bimodal microstructures and even superior electrochemical behavior compared with the plain UFG and CG materials in the 3.5% NaCl solution. The enhanced corrosion resistance is attributed to the optimum cathode to anode surface area ratio that gives rise to the formation of an effective galvanic couple between CG areas and the UFG matrix. The operational galvanic coupling leads to the domination of a “self-anodic protection system” on bimodal microstructure and consequently forms a uniform thick protective passive layer over it. In contrast, the 45 vol. % CG bimodal specimen shows the least corrosion resistance due to the catastrophic galvanic corrosion in UFG regions. The observed results for UFG Al6063 suggest that metallurgical tailoring of the grain structure in terms of bimodal microstructures leads to simultaneous enhancement in the electrochemical behavior and mechanical properties of passivable alloys that are usually inversely correlated. The mechanism of self-anodic protection for passivable metals with bimodal microstructures is discussed here for the first time.

ISO 9001 certification for hospitals in Bulgaria: does it help service?

Science.gov (United States)

Stoimenova, Assena; Stoilova, Ani; Petrova, Guenka

2014-03-04

The aim of our study is to review the published literature on establishment and implementation of ISO 9001 QMS in European hospitals, to study the availability of International Organization for Standardization (ISO) quality management systems (QMS) in Bulgarian hospitals and to outline the main advantages of ISO implementation in the hospitals in Bulgaria. The information on availability of ISO QMS in the hospitals in Bulgaria was gathered via Bulgarian certification register, the registries of various quality associations, websites of hospitals and certification companies presented in Bulgaria. A total number of 312 hospitals in Bulgaria were screened for the availability of QMS certified against the ISO 9001 requirements. The experience of European hospitals that implemented QMS is positive and the used approaches to improve the processes and the demonstrated effects from ISO implementation are analysed by the researchers. Unlike other European Union member states, the establishment of quality management systems in Bulgaria is not compulsory. However, our study revealed that 14.42% of the hospitals in Bulgaria have implemented and have certified quality systems against the requirements of ISO 9001. Our study confirmed that a quality management system using the ISO 9001 standard is useful for the hospitals as it can help to increase the operational efficiencies, to reduce errors, improve patient safety and produce a more preventive approach instead of a reactive environment.

Inter ISO Market Coordination by Calculating Border Locational Marginal Prices

Directory of Open Access Journals (Sweden)

BABIC, A. B.

2013-05-01

Full Text Available In this paper the methodology for solving Locational Marginal Price (LMP differences (inconsistency of LMPs that arise at the boundary buses between separate power markets is proposed. The algorithm developed enables us to obtain consistent LMP values at the boundary buses between interconnected ISOs. A Primal-Dual Interior Point based optimal power flow (OPF is applied, with complete set of power system physical limit constraints, to solve a regional spot market. The OPF is implemented such that producer and consumer behaviors are modeled simultaneously, while the welfare is maximized. In this paper a generalized methodology for multiple ISOs case is proposed and later it is practically applied on two interconnected independent entities. The algorithm for approximation of cost coefficients of generators and dispatchable loads for neighboring ISOs is proposed. The developed algorithm enables participating ISOs to obtain LMPs at the boundary buses with other interconnected ISOs. By controlling interchange of electric power at the scheduled level, regional spot markets are resolved eliminating possible exercise of market power by individual interconnected ISOs. Results of proposed methodology are tested on the IEEE 118-bus power system.

Spectra of globular clusters in the Sombrero galaxy: evidence for spectroscopic metallicity bimodality

Science.gov (United States)

Alves-Brito, Alan; Hau, George K. T.; Forbes, Duncan A.; Spitler, Lee R.; Strader, Jay; Brodie, Jean P.; Rhode, Katherine L.

2011-11-01

We present a large sample of over 200 integrated-light spectra of confirmed globular clusters (GCs) associated with the Sombrero (M104) galaxy taken with the Deep Imaging Multi-Object Spectrograph (DEIMOS) instrument on the Keck telescope. A significant fraction of the spectra have signal-to-noise ratio levels high enough to allow measurements of GC metallicities using the method of Brodie & Huchra. We find a distribution of spectroscopic metallicities in the range -2.2 < [Fe/H] < +0.1 that is bimodal, with peaks at [Fe/H]˜-1.4 and -0.6. Thus, the GC system of the Sombrero galaxy, like a few other galaxies now studied in detail, reveals a bimodal spectroscopic metallicity distribution supporting the long-held belief that colour bimodality reflects two metallicity subpopulations. This further suggests that the transformation from optical colour to metallicity for old stellar populations, such as GCs, is not strongly non-linear. We also explore the radial and magnitude distribution with metallicity for GC subpopulations but small number statistics prevent any clear trends in these distributions. Based on observations obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California and the National Aeronautics and Space Administration.

The dark side of ISO 14001: The symbolic environmental behavior

Directory of Open Access Journals (Sweden)

Vera Ferrón Vílchez

2017-01-01

Full Text Available Some of the academic research on ISO 14001 has focused on analyzing the benefits of its adoption. However, this international standard has also received some criticism, particularly in respect of the adoption of ISO 14001 when not accompanied by significant improvements in environmental performance. This study analyzes the relationship between the symbolic environmental behavior and the adoption of ISO 14001. In so doing, it uses binary logistic regression to analyze an international sample of 1961 manufacturing facilities that each employs more than 50 people. The results indicate that the higher the symbolic environmental performance of the firm, the greater the probability of adopting ISO 14001.

Acid-base and ion balance in fishes with bimodal respiration.

Science.gov (United States)

Shartau, R B; Brauner, C J

2014-03-01

The evolution of air breathing during the Devonian provided early fishes with bimodal respiration with a stable O2 supply from air. This was, however, probably associated with challenges and trade-offs in terms of acid-base balance and ionoregulation due to reduced gill:water interaction and changes in gill morphology associated with air breathing. While many aspects of acid-base and ionoregulation in air-breathing fishes are similar to water breathers, the specific cellular and molecular mechanisms involved remain largely unstudied. In general, reduced ionic permeability appears to be an important adaptation in the few bimodal fishes investigated but it is not known if this is a general characteristic. The kidney appears to play an important role in minimizing ion loss to the freshwater environment in the few species investigated, and while ion uptake across the gut is probably important, it has been largely unexplored. In general, air breathing in facultative air-breathing fishes is associated with an acid-base disturbance, resulting in an increased partial pressure of arterial CO2 and a reduction in extracellular pH (pHE ); however, several fishes appear to be capable of tightly regulating tissue intracellular pH (pHI ), despite a large sustained reduction in pHE , a trait termed preferential pHI regulation. Further studies are needed to determine whether preferential pHI regulation is a general trait among bimodal fishes and if this confers reduced sensitivity to acid-base disturbances, including those induced by hypercarbia, exhaustive exercise and hypoxia or anoxia. Additionally, elucidating the cellular and molecular mechanisms may yield insight into whether preferential pHI regulation is a trait ultimately associated with the early evolution of air breathing in vertebrates. © 2014 The Fisheries Society of the British Isles.

Deaf Parents of Cochlear-Implanted Children: Beliefs on Bimodal Bilingualism

Science.gov (United States)

Mitchiner, Julie Cantrell

2015-01-01

This study investigated 17 Deaf families in North America with cochlear-implanted children about their attitudes, beliefs, and practices on bimodal bilingualism (defined as using both a visual/manual language and an aural/oral language) in American Sign Language (ASL) and English. A survey and follow-up interviews with 8 families were conducted.…

ISO certification pays off in quality improvement

International Nuclear Information System (INIS)

Vermeer, F.J.G.

1992-01-01

This paper reports that by obtaining and maintaining International Standards Organization (ISO) 9001 certification, a company can improve its quality control system, cut waste, and motivate its employees. In so doing it improves its competitive position in both international and domestic markets. The success of a number of countries (notably Japan) in the world markets has focused the attention of the industrialized countries on improving quality levels and striving for a unified, worldwide quality standard. This has been particularly true in Europe; with several countries competing in a single market, a common quality standard has been a highly desirable goal for decades. One of the first multinational quality standards evolved in the European Community, which is estimated to become a single market with a gross national product of $4.5 trillion by 1992. As a consequence, in 1987 the International Standards Organization created ISO 9000, a single standard to ensure uniform quality in products and services offered with this growing market. U.S. petroleum and natural gas companies must recognize and implement the ISO 9000 standards or possibly lose international markets. If the present worldwide trend towards ISO 9000 continues (and there is no reason to believe that it will not), the standards will be just as important in the domestic market

The impact of ISO 14000 on developing world businesses

International Nuclear Information System (INIS)

Mohamed, S.T.

2001-01-01

ISO 14000 has attracted interest from industry, international organizations and governments around the globe. Policy-makers and industry both appear to be looking to the standards as a key component of a new paradigm for cooperation between regulators and industry. This realization seems to have resulted from a growing awareness that the fragmented, reactive approach to environmental management in the past has not produced optimal results. Businesses are realizing the value of integrating their compliance procedures for each regulation into a broader system. Compliance problems can often be linked to system problems such as inadequate training, lack of responsibility at the right level, inadequate data, and other related causes. An effective Environmental Management System (EMS) eliminates these pitfalls. The evolution of the EMS is being shaped by market forces, ISO 9000, regulatory shifts, public awareness, and cost implications for ISO certifications. The transformation of these management practices is not limited to industrialized countries. In anticipation of the non-tariff trade barriers that could be erected as a result of these standards, many developing countries are seeking avenues of compliance with ISO 14000's requirements. Egypt should be concerned with the implementation of this system, for firms in countries of the European Community (EC) have been given explicit instructions by the three prevalent European standard-setting organizations to ''familiarize'' themselves with the requirements of ISO 14000. This paper will focus primarily on the expected effects of ISO 14001. (author)

Multiphase flow modeling of a crude-oil spill site with a bimodal permeability distribution

Science.gov (United States)

Dillard, Leslie A.; Essaid, Hedeff I.; Herkelrath, William N.

1997-01-01

Fluid saturation, particle-size distribution, and porosity measurements were obtained from 269 core samples collected from six boreholes along a 90-m transect at a subregion of a crude-oil spill site, the north pool, near Bemidji, Minnesota. The oil saturation data, collected 11 years after the spill, showed an irregularly shaped oil body that appeared to be affected by sediment spatial variability. The particle-size distribution data were used to estimate the permeability (k) and retention curves for each sample. An additional 344 k estimates were obtained from samples previously collected at the north pool. The 613 k estimates were distributed bimodal lognormally with the two population distributions corresponding to the two predominant lithologies: a coarse glacial outwash deposit and fine-grained interbedded lenses. A two-step geostatistical approach was used to generate a conditioned realization of k representing the bimodal heterogeneity. A cross-sectional multiphase flow model was used to simulate the flow of oil and water in the presence of air along the north pool transect for an 11-year period. The inclusion of a representation of the bimodal aquifer heterogeneity was crucial for reproduction of general features of the observed oil body. If the bimodal heterogeneity was characterized, hysteresis did not have to be incorporated into the model because a hysteretic effect was produced by the sediment spatial variability. By revising the relative permeability functional relation, an improved reproduction of the observed oil saturation distribution was achieved. The inclusion of water table fluctuations in the model did not significantly affect the simulated oil saturation distribution.

Iso-α-acids, bitter components of beer, prevent obesity-induced cognitive decline.

Science.gov (United States)

Ayabe, Tatsuhiro; Ohya, Rena; Kondo, Keiji; Ano, Yasuhisa

2018-03-19

Dementia and cognitive decline have become worldwide public health problems, and it was recently reported that life-style related diseases and obesity are key risk factors in dementia. Iso-α-acids, hop-derived bitter components of beer, have been reported to have various physiological functions via activation of peroxisome proliferator-activated receptor γ. In this report, we demonstrated that daily intake of iso-α-acids suppresses inflammations in the hippocampus and improves cognitive decline induced by high fat diet (HFD). Body weight, epididymal fat weight, and plasma triglyceride levels were increased in HFD-fed mice, and significantly decreased in iso-α-acids supplemented HFD-fed mice. HFD feeding enhances the production of inflammatory cytokines and chemokines, such as TNF-α, which was significantly suppressed by iso-α-acids administration. HFD-induced neuroinflammation caused lipid peroxidation, neuronal loss, and atrophy in hippocampus, and those were not observed in iso-α-acids-treated mice. Furthermore, iso-α-acids intake significantly improved cognitive decline induced by HFD-feeding. Iso-α-acids are food derived components that suppressing both lipid accumulation and brain inflammation, thus iso-α-acids might be beneficial for the risk of dementia increased by obesity and lifestyle-related diseases.

New water and remote galaxies complete ISO's observations

Science.gov (United States)

ISO's operational teams at ESA's ground station at Villafranca near Madrid have been hurrying to provide the world's astronomers with as many observations as possible. They have long anticipated the exhaustion of ISO's vital supply of liquid helium, which cooled the infrared telescope and its instruments to their operating temperatures, close to absolute zero. Two weeks after ISO was put into orbit on 17 November 1995 by an Ariane 44P launcher, the external parts of the cooling system had settled to the operating temperature. The specification required that ISO should then operate for at least 18 months -- implying that operations might have to end in May 1997. Thanks to superb engineering by European industry, which built the spacecraft and its super-cool telescope, ISO has given astronomers almost a year longer than that. During the extra time the count of ISO's observations of cosmic objects has risen from 16,000 to about 26,000. Among the benefits of ISO's longevity has been the chance to examine an important region of the sky, in and around the constellation of Orion. This was not accessible in the nominal mission but has now been observed in two periods. Four inter national teams, supported by national funding agencies, supplied the instruments to analyse the infrared rays received by ISO's telescope. The principal investigators leading the teams are Dietrich Lemke (Heidelberg, Germany) for the versatile photometer ISOPHOT, Catherine Cesarsky (Saclay, France) for the camera ISOCAM, Thijs de Graauw (Groningen, the Netherlands) for the Short Wavelength Spectrometer SWS, and Peter Clegg (London, UK) for the Long Wavelength Spectrometer LWS. Water vapour on Titan A big difference between ISO and the only previous infrared astronomy satellite (IRAS 1983) has been its ability to examine individual objects across a wide range of accurately defined infrared wavelengths. Many spectra showing patterns of intensities at the different wavelengths have enabled astronomers

The ISO 50001 Impact Estimator Tool (IET 50001 V1.1.4) - User Guide and Introduction to the ISO 50001 Impacts Methodology

Energy Technology Data Exchange (ETDEWEB)

Therkelsen, Peter L. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rao, Prakash [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Aghajanzadeh, Arian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McKane, Aimee T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2016-08-01

ISO 50001-Energy management systems – Requirements with guidance for use, is an internationally developed standard that provides organizations with a flexible framework for implementing an energy management system (EnMS) with the goal of continual energy performance improvement. The ISO 50001 standard was first published in 2011 and has since seen growth in the number of certificates issued around the world, primarily in the industrial (agriculture, manufacturing, and mining) and service (commercial) sectors. Policy makers in many regions and countries are looking to or are already using ISO 50001 as a basis for energy efficiency, carbon reduction, and other energy performance improvement schemes. The Impact Estimator Tool 50001 (IET 50001 Tool) is a computational model developed to assist researchers and policy makers determine the potential impact of ISO 50001 implementation in the industrial and service (commercial) sectors for a given region or country. The IET 50001 Tool is based upon a methodology initially developed by the Lawrence Berkeley National Laboratory that has been improved upon and vetted by a group of international researchers. By using a commonly accepted and transparent methodology, users of the IET 50001 Tool can easily and clearly communicate the potential impact of ISO 50001 for a region or country.

The Centaurus cluster of galaxies. II. The bimodal-velocity structure

International Nuclear Information System (INIS)

Lucey, J.R.; Currie, M.J.; Dickens, R.J.

1985-09-01

This is the second paper in a series that describes an extensive study of the Centaurus cluster of galaxies. The paper concerns the bimodal velocity distribution of the galaxies in the cluster. The likely location of the two main cluster components is discussed. The data strongly favours the hypothesis that the two components lie within the same cluster. (UK)

ISO 50001 and SEP Faster and Cheaper - Exploring the Enterprise-Wide Approach

Energy Technology Data Exchange (ETDEWEB)

Liu, Jingjing [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rao, Prakash [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Therkelsen, Peter [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sheaffer, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Scheihing, Paul [USDOE, Washington, DC (United States); Tamm, Yannick [Energetics, Inc. (United States)

2017-06-01

ISO 50001 and other management systems (e.g., ISO 9001 and ISO 14001) allow for implementation and certification at the enterprise level. The "Central Office" concept, which allows a small group of employees to manage and facilitate the organization’s energy management system (EnMS) at the enterprise level, was introduced within the ISO 50003 standard to provide guidance to ISO 50001 certification bodies. Four industrial companies have partnered with the United States Department of Energy to pilot the enterprise-wide ISO 50001/SEP concept under the Better Buildings Superior Energy Performance (SEP) Enterprise-wide Accelerator. Each organization developed a Central Office to host their EnMS while implementing ISO 50001/SEP at multiple physically separated sites. The four corporate partners tailored their Central Office implementation model to meet their own specific circumstances and needs. This paper reviews the commonalities, differences, and benefits of each of these enterprise-wide implementation models, including organizational structures, Central Office staff responsibilities, and key strategies. The cost savings and benefits of using the enterprise-wide approach were assessed, including the cost per site compared with that of a conventional, single-site ISO 50001/SEP implementation approach. This paper also discusses the drivers for the cost reductions realized through these enterprise-wide approaches. The four partner companies worked with 30 total sites. On average, these 30 sites improved energy performance by 5% annually over their SEP achievement periods, saved more than $600,000 annually in energy costs and reduced implementation cost for ISO 50001 and SEP by $19,000 and 0.8 Full Time Equivalent × years (FTE-yr) of staff time per site. The results can inform other organizations seeking to implement enterprise-wide ISO 50001/SEP, as well as energy efficiency organizations seeking to promote wider adoption of ISO 50001 implementation.

Implementation of ISO guide 25 in a medical dosimetry secondary standards calibration laboratory

International Nuclear Information System (INIS)

DeWerd, L.A.

1995-01-01

Currently, there is a great deal of discussion among industry and government agencies about ISO 9000 accreditation. U.S. manufacturers with ISO 9000 accreditation are regarded more favorably by European countries. The principles behind the ISO 9000 accreditation are based on the Total Quality Management (TQM) principles that are being implemented in many U.S. industries. This paper will deal only with the calibration issue. There is a difference in the areas covered by ISO 9000 and ISO Guide 25 documents. ISO 9000, in particular ISO 9001 - ISO 9003, cover the open-quotes calibrationclose quotes of inspection, measuring and test equipment. This equipment is basically used for open-quotes factory calibrationsclose quotes to determine that equipment is performing within manufacturer specifications. ISO Guide 25 is specifically for open-quotes calibration and testing laboratories,close quotes generally laboratories that have painstaking procedures to reduce uncertainties and establish high accuracy of the transfer of calibration. The experience of the University of Wisconsin Accredited Dosimetry Calibration Laboratory in conforming to ISO Guide 25 will be outlined. The entire laboratory staff must become familiar with the process and an individual with direct authority must become the one to maintain the quality of equipment and calibrations in the role of open-quotes quality-assurance manager.close quotes

NERVA-Derived Concept for a Bimodal Nuclear Thermal Rocket

International Nuclear Information System (INIS)

Fusselman, Steven P.; Frye, Patrick E.; Gunn, Stanley V.; Morrison, Calvin Q.; Borowski, Stanley K.

2005-01-01

The Nuclear Thermal Rocket is an enabling technology for human exploration missions. The 'bimodal' NTR (BNTR) provides a novel approach to meeting both propulsion and power requirements of future manned and robotic missions. The purpose of this study was to evaluate tie-tube cooling configurations, NTR performance, Brayton cycle performance, and LOX-Augmented NTR (LANTR) feasibility to arrive at a point of departure BNTR configuration for subsequent system definition

Perancangan SMKI Berdasarkan SNI ISO/IEC27001:2013 dan SNI ISO/IEC27005:2013 (Studi Kasus DPTSI-ITS

Directory of Open Access Journals (Sweden)

Furqon Mauladani

2018-03-01

Full Text Available Institut Teknologi Sepuluh Nopember (ITS adalah salah satu universitas di Surabaya. ITS telah menggunakan TIK untuk keperluan operasional bisnisnya (contohnya isi kartu program studi, proses absensi, pembaharuan informasi, dan lainnya. Penggunaan TIK tidak dapat dipisahkan dari ancaman yang dapat mengganggu operasional TIK. Ancaman terdiri dari ancaman yang berasal dari luar (penyebaran malware, aktifitas social engineering, orang dalam (sengaja, tidak sengaja, kegagalan teknis (kesalahan penggunaan, kegagalan perangkat keras/lunak ataupun bencana alam (kebakaran, gempa, banjir. Metode yang digunakan pada penelitian ini adalah melakukan manajemen resiko keamanan informasi berdasarkan SNI ISO/IEC 27005 dan perancangan dokumen SMKI berdasarkan SNI ISO/IEC 27001. Hasil penelitian ini adalah 60 resiko yang tidak diterima dari total 228 resiko yang telah teridentifikasi. Dari 60 resiko tersebut, terdapat 58 risk modification, 1 risk avoidance, dan 1 risk sharing. Tata kelola keamanan informasi yang dirancang berdasarkan SNI ISO/IEC 27001 adalah ruang lingkup SMKI, kebijakan SMKI, proses penilaian resiko, proses penanganan resiko, statement of applicability, dan sasaran keamanan informasi.

Standardization by ISO to Ensure the Sustainability of Space Activities

Science.gov (United States)

Kato, A.; Lazare, B.; Oltrogge, D.; Stokes, H.

2013-08-01

The ISO / Technical Committee 20 / Sub-committee 14 develops debris-related standards and technical reports to mitigate debris and help ensure mission and space sustainability. While UN Guidelines and the IADC Guidelines encourage national governments and agencies to promote debris mitigation design and operation, the ISO standards will help the global space industry promote and sustain its space-related business. In this paper the scope and status of each ISO standard is discussed within an overall framework. A comparison with international guidelines is also provided to demonstrate the level of consistency. Finally, as a case study, the ISO standards are applied to a CubeSat mission, thus demonstrating their usability on a relatively recent and popular class of satellite.

Isoe - information system on occupational exposure. Ten years of experience

International Nuclear Information System (INIS)

2002-01-01

The information System on Occupational Exposure (ISOE) was created in 1992 to provide a forum for radiation protection experts from both utilities and national regulatory authorities to discuss, promote and co-ordinate international co-operative undertakings in the area of worker protection at nuclear power plants. The ISOE System is jointly managed by the OECD Nuclear Energy Agency (NEA) and the International Atomic Energy Agency (IAEA). This report provides an overview of the experience gained from, and benefits provided by, the ISOE System over the past ten years. Active participation of a large number of utilities in ISOE has contributed to a reduction in occupational exposure at nuclear power plants worldwide. (authors)

Combining bimodal presentation schemes and buzz groups improves clinical reasoning and learning at morning report.

Science.gov (United States)

Balslev, Thomas; Rasmussen, Astrid Bruun; Skajaa, Torjus; Nielsen, Jens Peter; Muijtjens, Arno; De Grave, Willem; Van Merriënboer, Jeroen

2014-12-11

Abstract Morning reports offer opportunities for intensive work-based learning. In this controlled study, we measured learning processes and outcomes with the report of paediatric emergency room patients. Twelve specialists and 12 residents were randomised into four groups and discussed the same two paediatric cases. The groups differed in their presentation modality (verbal only vs. verbal + text) and the use of buzz groups (with vs. without). The verbal interactions were analysed for clinical reasoning processes. Perceptions of learning and judgment of learning were reported in a questionnaire. Diagnostic accuracy was assessed by a 20-item multiple-choice test. Combined bimodal presentation and buzz groups increased the odds ratio of clinical reasoning to occur in the discussion of cases by a factor of 1.90 (p = 0.013), indicating superior reasoning for buzz groups working with bimodal materials. For specialists, a positive effect of bimodal presentation was found on perceptions of learning (p presentation on diagnostic accuracy was noted in the specialists (p presentation and buzz group discussion of emergency cases improves clinicians' clinical reasoning and learning.

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.

Science.gov (United States)

Li, Qing; Bohin, Natacha; Wen, Tiffany; Ng, Victor; Magee, Jeffrey; Chen, Shann-Ching; Shannon, Kevin; Morrison, Sean J

2013-12-05

'Pre-leukaemic' mutations are thought to promote clonal expansion of haematopoietic stem cells (HSCs) by increasing self-renewal and competitiveness; however, mutations that increase HSC proliferation tend to reduce competitiveness and self-renewal potential, raising the question of how a mutant HSC can sustainably outcompete wild-type HSCs. Activating mutations in NRAS are prevalent in human myeloproliferative neoplasms and leukaemia. Here we show that a single allele of oncogenic Nras(G12D) increases HSC proliferation but also increases reconstituting and self-renewal potential upon serial transplantation in irradiated mice, all prior to leukaemia initiation. Nras(G12D) also confers long-term self-renewal potential to multipotent progenitors. To explore the mechanism by which Nras(G12D) promotes HSC proliferation and self-renewal, we assessed cell-cycle kinetics using H2B-GFP label retention and 5-bromodeoxyuridine (BrdU) incorporation. Nras(G12D) had a bimodal effect on HSCs, increasing the frequency with which some HSCs divide and reducing the frequency with which others divide. This mirrored bimodal effects on reconstituting potential, as rarely dividing Nras(G12D) HSCs outcompeted wild-type HSCs, whereas frequently dividing Nras(G12D) HSCs did not. Nras(G12D) caused these effects by promoting STAT5 signalling, inducing different transcriptional responses in different subsets of HSCs. One signal can therefore increase HSC proliferation, competitiveness and self-renewal through bimodal effects on HSC gene expression, cycling and reconstituting potential.

[Efforts to achieve and effects of acquiring ISO 15189 in Tokushima University Hospital].

Science.gov (United States)

Shono, Kazuko; Kishi, Misako; Satou, Mituyo; Nagamine, Yasunori; Doi, Tosio

2009-12-01

The medical laboratory of Tokushima University Hospital acquired ISO 15189, an international standard for medical laboratories, on July 6th, 2007, resulting in it achieving the 24th place in Japan and 5th place among national university hospitals. The first surveillance was just performed on October 6th, 2008. Tokushima University Hospital, in which our medical laboratory is included as one section, already succeeded in acquiring ISO 9001, PrivacyMark System, and Quality Health Care ver. 5 before accomplishing ISO 15189. To achieve ISO 15189, we prepared documents based on ISO 9001 without any consultation, resulting in a review of the difference between ISO 9001 and ISO 15189 after the preliminary survey. Although achieving ISO 15189 resulted in an improvement in the reliability of laboratory results and accuracy, leading to the development of our technical skills and awareness, and sharing of knowledge, we consider that the considerable investment of time to prepare the requirements remains to be overcome.

Noise exposure alters long-term neural firing rates and synchrony in primary auditory and rostral belt cortices following bimodal stimulation.

Science.gov (United States)

Takacs, Joseph D; Forrest, Taylor J; Basura, Gregory J

2017-12-01

We previously demonstrated that bimodal stimulation (spinal trigeminal nucleus [Sp5] paired with best frequency tone) altered neural tone-evoked and spontaneous firing rates (SFRs) in primary auditory cortex (A1) 15 min after pairing in guinea pigs with and without noise-induced tinnitus. Neural responses were enhanced (+10 ms) or suppressed (0 ms) based on the bimodal pairing interval. Here we investigated whether bimodal stimulation leads to long-term (up to 2 h) changes in tone-evoked and SFRs and neural synchrony (correlate of tinnitus) and if the long-term bimodal effects are altered following noise exposure. To obviate the effects of permanent hearing loss on the results, firing rates and neural synchrony were measured three weeks following unilateral (left ear) noise exposure and a temporary threshold shift. Simultaneous extra-cellular single-unit recordings were made from contralateral (to noise) A1 and dorsal rostral belt (RB); an associative auditory cortical region thought to influence A1, before and after bimodal stimulation (pairing intervals of 0 ms; simultaneous Sp5-tone and +10 ms; Sp5 precedes tone). Sixty and 120 min after 0 ms pairing tone-evoked and SFRs were suppressed in sham A1; an effect only preserved 120 min following pairing in noise. Stimulation at +10 ms only affected SFRs 120 min after pairing in sham and noise-exposed A1. Within sham RB, pairing at 0 and +10 ms persistently suppressed tone-evoked and SFRs, while 0 ms pairing in noise markedly enhanced tone-evoked and SFRs up to 2 h. Together, these findings suggest that bimodal stimulation has long-lasting effects in A1 that also extend to the associative RB that is altered by noise and may have persistent implications for how noise damaged brains process multi-sensory information. Moreover, prior to bimodal stimulation, noise damage increased neural synchrony in A1, RB and between A1 and RB neurons. Bimodal stimulation led to persistent changes in neural synchrony in

Preparation of mesoporous NiO with a bimodal pore size distribution and application in electrochemical capacitors

Energy Technology Data Exchange (ETDEWEB)

Wang Dengchao; Ni Wenbin; Pang Huan; Lu Qingyi; Huang Zhongjie [Key Laboratory of Analytical Chemistry for Life Science (MOE), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210008 (China); Zhao Jianwei, E-mail: zhaojw@nju.edu.c [Key Laboratory of Analytical Chemistry for Life Science (MOE), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210008 (China)

2010-09-01

Mesoporous nickel oxide with a porous structure exhibiting a bimodal pore size distribution (2.6 and 30.3 nm diameter pores) has been synthesized in this paper. Firstly, a mesoporous precursor of coordination complex Ni{sub 3}(btc){sub 2}.12H{sub 2}O (btc = 1,3,5-benzenrtricarboxylic acid) is synthesized based on the metal-organic coordination mechanism by a hydrothermal method. Then mesoporous NiO with a bimodal size distribution is obtained by calcining the precursor in the air, and characterized by transmission electron microscopy and N{sub 2} adsorption measurements. Such unique multiple porous structure indicates a promising application of the obtained NiO as electrode materials for supercapacitors. The electrochemical behavior has been investigated by cyclic voltammogram, electrochemical impedance spectra and chronopotentiometry in 3 wt.% KOH aqueous electrolyte. The results reveal that the prepared NiO has high-capacitance retention at high scan rate and exhibits excellent cycle-life stability due to its special mesoporous character with bimodal size distribution.

Bimodal microstructure and deformation of cryomilled bulk nanocrystalline Al-7.5Mg alloy

International Nuclear Information System (INIS)

Lee, Z.; Witkin, D.B.; Radmilovic, V.; Lavernia, E.J.; Nutt, S.R.

2005-01-01

The microstructure, mechanical properties and deformation response of bimodal structured nanocrystalline Al-7.5Mg alloy were investigated. Grain refinement was achieved by cryomilling of atomized Al-7.5Mg powders, and then cryomilled nanocrystalline powders blended with 15 and 30% unmilled coarse-grained powders were consolidated by hot isostatic pressing followed by extrusion to produce bulk nanocrystalline alloys. Bimodal bulk nanocrystalline Al-7.5Mg alloys, which were comprised of nanocrystalline grains separated by coarse-grain regions, show balanced mechanical properties of enhanced yield and ultimate strength and reasonable ductility and toughness compared to comparable conventional alloys and nanocrystalline metals. The investigation of tensile and hardness test suggests unusual deformation mechanisms and interactions between ductile coarse-grain bands and nanocrystalline regions

77 FR 11532 - Notice of Attendance at ISO New England and NEPOOL Meetings

Science.gov (United States)

2012-02-27

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Attendance at ISO New England... members of the Commission and Commission staff may attend upcoming ISO New England Inc. (ISO-NE) and New..., the Commission and Commission staff may monitor the various meetings posted on the ISO-NE Web site...

ISO 14001 ENVIRONMENTL MANAGEMENT SYSTEMS IN GOVERNMENT AND INDUSTRY

Science.gov (United States)

Two new USEPA documents address environmental management systems (EMS) from the perspectives of government and industry and are offered as tools for understanding the process of the ISO 14000 Standards development and usefulness of an EMS approach. The first document, ISO 14001 -...

IS ISO 9000 CERTIFICATION LOSING ITS CREDIBILITY?

Directory of Open Access Journals (Sweden)

P.R. Ramesh

2013-03-01

Full Text Available ISO certification was a great hope for many stakeholders in India for making the country strong in terms of quality practices. It was a blessing in disguise when in early nineties; buyers were imposing conditions that you should be ISO compliant to do business with them. ISO was a great system to bring in improvements in the way an organization functions. But unfortunately some have adopted a short cut approach in getting the certification done. It is only just before the audit team comes for re-inspection that firms start removing dust from the quality manual files so that they can pretend that that they follow those systems. But a real commitment to adhering to these systems is missing. The paper describes such scenario existing in some quarters in India and warns against such practices for the overall good of the system.

Bimodal grain-size distribution of Chinese loess, and its palaeoclimatic implications

NARCIS (Netherlands)

Sun, D.G.; Bloemendal, J.; Rea, D.K.; An, Z.S.; Vandenberghe, J.; Lu, H.; Su, R.; Liu, T.S.

2004-01-01

Grain-size analysis indicates that Chinese loess generally shows a bimodal distribution with a coarse and a fine component. The coarse component, comprising the main part of the loess, has pronounced kurtosis and is well sorted, which is interpreted to be the product of dust storms generated by

Resolving the age bimodality of galaxy stellar populations on kpc scales

NARCIS (Netherlands)

Zibetti, Stefano; Gallazzi, Anna R.; Ascasibar, Y.; Charlot, S.; Galbany, L.; García Benito, R.; Kehrig, C.; de Lorenzo-Cáceres, A.; Lyubenova, M.; Marino, R. A.; Márquez, I.; Sánchez, S. F.; van de Ven, G.; Walcher, C. J.; Wisotzki, L.

2017-01-01

Galaxies in the local Universe are known to follow bimodal distributions in the global stellar population properties. We analyse the distribution of the local average stellar population ages of 654 053 sub-galactic regions resolved on ˜1 kpc scales in a volume-corrected sample of 394 galaxies, drawn

ISO Results Presented at International Astronomical Union

Science.gov (United States)

1997-08-01

Some of the work being presented is collected in the attached ESA Information Note N 25-97, ISO illuminates our cosmic ancestry. A set of six colour images illustrating various aspects have also been released and are available at http://www.estec.esa.nl/spdwww/iso1808.htm or in hard copy from ESA Public Relations Paris (fax:+33.1.5369.7690). These pictures cover: 1. Distant but powerful infrared galaxies 2. A scan across the milky way 3. Helix nebula: the shroud of a dead star 4. Supernova remnant Cassiopeia A 5. Trifid nebula: a dusty birthplace of stars 6. Precursors of stars and planets The International Astronomical Union provides a forum where astronomers from all over the world can develop astronomy in all its aspects through international co-operation. General Assemblies are held every three years. It is expected that over 1600 astronomers will attend this year's meeting, which is being held in Kyoto, Japan from 18-30 August. Further information on the meeting can be found at: www.tenmon.or.jp/iau97/ . ISO illuminates our cosmic ancestry The European Space Agency's Infrared Space Observatory, ISO, is unmatched in its ability to explore and analyse many of the universal processes that made our existence possible. We are children of the stars. Every atom in our bodies was created in cosmic space and delivered to the Sun's vicinity in time for the Earth's formation, during a ceaseless cycle of birth, death and rebirth among the stars. The most creative places in the sky are cool and dusty, and opaque even to the Hubble Space Telescope. Infrared rays penetrating the dust reveal to ISO hidden objects, and the atoms and molecules of cosmic chemistry. "ISO is reading Nature's recipe book," says Roger Bonnet, ESA's director of science. "As the world's only telescope capable of observing the Universe over a wide range of infrared wavelengths, ISO plays an indispensable part in astronomical discoveries that help to explain how we came to exist." This Information Note

Bimodal stimulus timing-dependent plasticity in primary auditory cortex is altered after noise exposure with and without tinnitus.

Science.gov (United States)

Basura, Gregory J; Koehler, Seth D; Shore, Susan E

2015-12-01

Central auditory circuits are influenced by the somatosensory system, a relationship that may underlie tinnitus generation. In the guinea pig dorsal cochlear nucleus (DCN), pairing spinal trigeminal nucleus (Sp5) stimulation with tones at specific intervals and orders facilitated or suppressed subsequent tone-evoked neural responses, reflecting spike timing-dependent plasticity (STDP). Furthermore, after noise-induced tinnitus, bimodal responses in DCN were shifted from Hebbian to anti-Hebbian timing rules with less discrete temporal windows, suggesting a role for bimodal plasticity in tinnitus. Here, we aimed to determine if multisensory STDP principles like those in DCN also exist in primary auditory cortex (A1), and whether they change following noise-induced tinnitus. Tone-evoked and spontaneous neural responses were recorded before and 15 min after bimodal stimulation in which the intervals and orders of auditory-somatosensory stimuli were randomized. Tone-evoked and spontaneous firing rates were influenced by the interval and order of the bimodal stimuli, and in sham-controls Hebbian-like timing rules predominated as was seen in DCN. In noise-exposed animals with and without tinnitus, timing rules shifted away from those found in sham-controls to more anti-Hebbian rules. Only those animals with evidence of tinnitus showed increased spontaneous firing rates, a purported neurophysiological correlate of tinnitus in A1. Together, these findings suggest that bimodal plasticity is also evident in A1 following noise damage and may have implications for tinnitus generation and therapeutic intervention across the central auditory circuit. Copyright © 2015 the American Physiological Society.

Revision of the ISO and EN radiation sterilization standards

DEFF Research Database (Denmark)

Miller, A.; Hansen, J.

2002-01-01

The radiation sterilization standards, ISO 11137 and EN 552, are now being revised under "ISO lead", with the aim of producing only one international standard, although in four parts: (1) requirements. (2) dose-setting methods, (3) dose-substantiation methods and (4) dosimetry. Several aspects...

Measuring the Software Product Quality during the Software Development Life-Cycle: An ISO Standards Perspective

OpenAIRE

Rafa E. Al-Qutaish

2009-01-01

Problem statement: The International Organization for Standardization (ISO) published a set of international standards related to the software engineering, such as ISO 12207 and ISO 9126. However, there is a set of cross-references between the two standards. Approach: The ISO 9126 on software product quality and ISO 12207 on software life cycle processes had been analyzed to invistigate the relationships between them and to make a mapping from the ISO 9126 quality characteristics to the ISO 1...

Bimodality emerges from transport model calculations of heavy ion collisions at intermediate energy

Science.gov (United States)

Mallik, S.; Das Gupta, S.; Chaudhuri, G.

2016-04-01

This work is a continuation of our effort [S. Mallik, S. Das Gupta, and G. Chaudhuri, Phys. Rev. C 91, 034616 (2015)], 10.1103/PhysRevC.91.034616 to examine if signatures of a phase transition can be extracted from transport model calculations of heavy ion collisions at intermediate energy. A signature of first-order phase transition is the appearance of a bimodal distribution in Pm(k ) in finite systems. Here Pm(k ) is the probability that the maximum of the multiplicity distribution occurs at mass number k . Using a well-known model for event generation [Botzmann-Uehling-Uhlenbeck (BUU) plus fluctuation], we study two cases of central collision: mass 40 on mass 40 and mass 120 on mass 120. Bimodality is seen in both the cases. The results are quite similar to those obtained in statistical model calculations. An intriguing feature is seen. We observe that at the energy where bimodality occurs, other phase-transition-like signatures appear. There are breaks in certain first-order derivatives. We then examine if such breaks appear in standard BUU calculations without fluctuations. They do. The implication is interesting. If first-order phase transition occurs, it may be possible to recognize that from ordinary BUU calculations. Probably the reason this has not been seen already is because this aspect was not investigated before.

Bimodal Bilingual Language Development of Hearing Children of Deaf Parents

Science.gov (United States)

Hofmann, Kristin; Chilla, Solveig

2015-01-01

Adopting a bimodal bilingual language acquisition model, this qualitative case study is the first in Germany to investigate the spoken and sign language development of hearing children of deaf adults (codas). The spoken language competence of six codas within the age range of 3;10 to 6;4 is assessed by a series of standardised tests (SETK 3-5,…

Disentangling the climate-driven bimodal growth pattern in coastal and continental Mediterranean pine stands.

Science.gov (United States)

Pacheco, Arturo; Camarero, J Julio; Ribas, Montse; Gazol, Antonio; Gutierrez, E; Carrer, Marco

2018-02-15

Mediterranean climate promotes two distinct growth peaks separated by summer quiescence in trees. This bimodal pattern has been associated to favourable growing conditions during spring and autumn when mild temperatures and soil-water availability enhance cambial activity. Climatic models predict progressive warming and drying for the Mediterranean Basin, which could shorten or shift the spring and autumn growing seasons. We explored this idea by comparing two sites with different Mediterranean climate types (continental/dry and coastal/wet) and studied how climate drives the bimodal growth pattern in Aleppo pine (Pinus halepensis). Specifically we investigated the intra-annual changes in wood anatomy and the corresponding formation of density fluctuations (IADF). Trees on both sites were analyzed by dendrometer monitoring and by developing chronologies of wood anatomical traits. Radial-increment dynamics followed a similar bimodal pattern in both sites but coastal trees showed higher increments during the spring and autumn growth peaks, especially in autumn. The summer rest of cambium activity occurs almost one month earlier in the coastal than in the inland site. Lumen area and cell-wall thickness were significantly smaller in the continental site, while the increment rate of cell-wall thickness during an IADF event was much higher in the coastal pines. The accumulated soil moisture deficit was the main climatic constraint of tracheid enlargement in continental pines. Intra-annual density fluctuations were more frequent in the coastal trees where wood anatomy features recover to average values after such events, meanwhile inland trees presented a much lower recovery rate. Growth bimodality and the formation of density fluctuations were linked, but mild climate of the coastal site allows a longer growing season, which explains why trees in this area showed higher and more variable growth rates. Copyright © 2017 Elsevier B.V. All rights reserved.

'Bi-modal' isoscalar giant dipole strength in 58Ni

International Nuclear Information System (INIS)

Nayak, B.K.; Garg, U.; Hedden, M.; Koss, M.; Li, T.; Liu, Y.; Madhusudhana Rao, P.V.; Zhu, S.; Itoh, M.; Sakaguchi, H.; Takeda, H.; Uchida, M.; Yasuda, Y.; Yosoi, M.; Fujimura, H.; Fujiwara, M.; Hara, K.; Kawabata, T.; Akimune, H.; Harakeh, M.N.

2006-01-01

The strength distribution of the isoscalar giant dipole resonance (ISGDR) in 58 Ni has been obtained over the energy range 10.5-49.5 MeV via extreme forward angle scattering (including 0 deg.) of 386 MeV α particles. We observe a 'bi-modal' E1 strength distribution for the first time in an A<90 nucleus. The observed ISGDR strength distribution is in reasonable agreement with the predictions of a recent RPA calculation

ISO CD 14492

DEFF Research Database (Denmark)

Martins, Bo; Kossentini, F.; Arps, R.

1998-01-01

This Recommendation | International Standard, informally called JBIG2, defines a coding method for bilevel images, that is, images consisting of a single rectangular bit plane, with each pixel taking on one of just two possible colors. Itis being drafted by the Joint Bi-level Image Experts Group ...... (JBIG), a "Collaborative team" that reports both to ISO/IEC JTC1/SC29/WG1 and to ITU-T/SG8....

Implications of ISO 9000 for personnel dosimetry

International Nuclear Information System (INIS)

Yoder, R.C.

1995-01-01

Landauer, Inc. has gained approval to provide personnel dosimetry services in several countries. Each experiene reflects the different concerns adopted by national approval agencies. None have adopted ISO 9000 registration as evidence of a suitable quality system of management. Instead, each organization has prepared its own set of requirements with no provisions for recognizing the results of performance tests or audits conducted by other approval organizations. As ISO 9000 has become a communication symbol for commercial organizations dealing with each other, it has not been similarly viewed by radiation regulation bodies. A key reason arises from a tradition to regulate bodies. A key reason arises from a tradition to regulate, not promote, international trade, not encourage innovation, nor foster economic competition. A second reason is the inability to separate the technical requirements from quality assurance. ISO 9000 may become useful once the national technical organizations learn to trust those of other countries

IMPLEMENTASI SISTEM MANAJEMEN MUTU BERBASIS ISO 9001:2000 PADA SEKOLAH MENENGAH KEJURUAN

Directory of Open Access Journals (Sweden)

Mardi Wiyono

2012-09-01

Full Text Available Abstract: The implementation of ISO 9001:2000 quality management system in vocational school. The needs of quality products and services is largerly expanded in various organizations including education. Recently, the vocational schools also realize how important the quality product and service is. For achieving the quality product or service, some organizations implement the concept of ISO 9001:2000 quality management system. In 2006/2007 it is reported that there are some vocational schools have been certified with ISO 9001:2000. ISO 9001 is a serial document consists of Quality Management System Standard which has been refised from its previous standard. ISO 9001:2000 gives a number of prerequisites for organizations having business initialized by design and development, production, installations, and services. The vocational schools which have been certified with ISO 9001:2000, have to be re-accredited after three years of implementation.

Modelovanje georeferenciranih podataka u katastru nepokretnosti primenom ISO 19100 serije standarda / Spatial data modeling in the real estate cadastre using ISO 19100 series of standards

Directory of Open Access Journals (Sweden)

Mirko N. Petrović

2010-01-01

Full Text Available Potreba za standardizacijom u oblasti geografskih informacionih sistema odavno postoji. Međunarodne aktivnosti na ovom polju rezultirale su uspostavljanjem ISO 19100 serije standarda, kojima se regulišu različiti aspekti na polju geoinformatike. U članku su opisane mogućnosti primene relevantnih standarda iz serije ISO 19100 u modelovanju georeferenciranih podataka za katastar nepokretnosti. / Introduction Standardization in geo-information technologies contributes to the establishment of efficient information functions, their greater stability and easier transition. Application of international, national and internal standards in the process of developing software products in the field of geo-information technology creates conditions for the development of efficient, low cost, reliable and secure software products. Spatial data modeling basics for real estate cadastre In terms of modeling, the spatial information of real estate cadastre is based on the vector data model which is suitable for modeling objects with a smaller number of properties with emphasis on the position. The vector spatial data model consists of two components: spatial and descriptive. The basis of the spatial one is geometry that contains metric data usually given in coordinates of a reference system. Geometry and Topology uniquely determine the shape, size and position of the object model in space, i.e. they represent its spatial component. Merging the spatial component with the descriptive one results in a completely defined object from the real world. Elements of spatial data quality Spatial data quality can be reviewed through a set of the following elements: origin, positional accuracy, attribute accuracy, completeness, logical consistency, semantic accuracy and the time information. The elements of spatial data quality listed above are provided using ISO 19100 series of standards. Application of ISO19100 series of standards in spatial data modeling for real

Reasons to Adopt ISO 50001 Energy Management System

Directory of Open Access Journals (Sweden)

Frederic Marimon

2017-09-01

Full Text Available Purpose: The main aim of this paper is to analyze the relationships between the corporate motivations that lead organizations to establish the ISO 50001 Energy Management System (EnMS standard, and the difficulties and benefits derived from its adoption. Design/methodology/approach: Three independent exploratory factor analyses (EFA were conducted in order to identify (i sources of motivation: social requirements, ecology drivers, and competitive advantage; (ii the difficulties of an ISO 50001 adoption: operational difficulties and organizational difficulty; and (iii types of benefits: ecological benefits and operational benefits. In a second step, an exploratory path analysis, performed through Structural Equation Modeling (SEM, was used to analyze the relations among motivation, difficulties, and benefits related to the adoption of the ISO 50001 standard. Findings: Social requirements explain operational difficulties, which in turn impacts on operational benefits. Ecology drivers are directly related to ecological benefits. Organizational difficulties have an inverse relationship with operational and ecological benefits. Operational difficulties are related to operational benefits and ecological benefits. Research limitations/implications: The questionnaire was disseminated to 87 Spanish companies with ISO 50001 certification. Managers and other practitioners such as consultants, auditing companies, and official organizations in charge of developing standards might find useful implications. Originality/value: The standard was published in 2011 by the International Organization for Standardization (ISO. This paper contributes to assessment of the benefits of the standard by collecting information directly from the pioneer organizations that have adopted it, and provides clues on how to implement the standard and improve it in future.

Energy care in relation to your management system. Linking lists between the Reference Energy Care and ISO 14001, ISO 9001 and HACCP; Energiezorg in relatie tot uw zorgsysteem. Linking lists tussen de Referentie Energiezorg en ISO 14001, ISO 9001 en HACCP

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

Several so-called care systems are in use at institutes and companies. For efficiency reasons it makes sense to integrate an energy care system to the existing care system. For the so-called Reference Energy Care, developed by the Netherlands Agency for Energy and the Environment (Novem) links to three of the most important care systems have been elaborated: environmental care according to ISO 14001, the quality care system ISO 9001:2000 and the food safety system Hazard Analysis Critical Control Points (HACCP). The elaboration resulted in three tables, indicating the connections ('linking lists') between each of those care systems and the Reference Energy Care system and how energy care can be integrated into those systems. [Dutch] Bij instellingen en bedrijven zijn diverse zorgsystemen in gebruik. Het is zinvol om energiezorg - waar mogelijk - in een dergelijk bestaand systeem op te nemen. Meerdere zorgsystemen naast elkaar in stand houden is minder efficient dan de systemen integreren tot een systeem. Novem heeft daarom voor haar Referentie Energiezorg de link laten uitwerken naar drie van de meest voorkomende systemen: milieuzorg volgens ISO 14001, het kwaliteitszorgsysteem ISO 9001:2000 en het voedselveiligheidssysteem HACCP (Hazard Analysis Critical Control Points). Hieruit zijn drie tabellen voortgekomen, die aangeven welke verbanden er zijn tussen elk van deze zorgsystemen en de Referentie Energiezorg en hoe u energiezorg kunt integreren in elk van deze systemen. Deze tabellen worden aangeduid als 'linking lists' en u kunt ze gebruiken als hulpmiddel bij het integreren van energiezorg in uw eigen zorgsysteem. U vindt ze in deze brochure.

Energy care in relation to your management system. Linking lists between the Reference Energy Care and ISO 14001, ISO 9001 and HACCP; Energiezorg in relatie tot uw zorgsysteem. Linking lists tussen de Referentie Energiezorg en ISO 14001, ISO 9001 en HACCP

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

Several so-called care systems are in use at institutes and companies. For efficiency reasons it makes sense to integrate an energy care system to the existing care system. For the so-called Reference Energy Care, developed by the Netherlands Agency for Energy and the Environment (Novem) links to three of the most important care systems have been elaborated: environmental care according to ISO 14001, the quality care system ISO 9001:2000 and the food safety system Hazard Analysis Critical Control Points (HACCP). The elaboration resulted in three tables, indicating the connections ('linking lists') between each of those care systems and the Reference Energy Care system and how energy care can be integrated into those systems. [Dutch] Bij instellingen en bedrijven zijn diverse zorgsystemen in gebruik. Het is zinvol om energiezorg - waar mogelijk - in een dergelijk bestaand systeem op te nemen. Meerdere zorgsystemen naast elkaar in stand houden is minder efficient dan de systemen integreren tot een systeem. Novem heeft daarom voor haar Referentie Energiezorg de link laten uitwerken naar drie van de meest voorkomende systemen: milieuzorg volgens ISO 14001, het kwaliteitszorgsysteem ISO 9001:2000 en het voedselveiligheidssysteem HACCP (Hazard Analysis Critical Control Points). Hieruit zijn drie tabellen voortgekomen, die aangeven welke verbanden er zijn tussen elk van deze zorgsystemen en de Referentie Energiezorg en hoe u energiezorg kunt integreren in elk van deze systemen. Deze tabellen worden aangeduid als 'linking lists' en u kunt ze gebruiken als hulpmiddel bij het integreren van energiezorg in uw eigen zorgsysteem. U vindt ze in deze brochure.

21 CFR 184.1165 - n-Butane and iso-butane.

Science.gov (United States)

2010-04-01

... FOR HUMAN CONSUMPTION (CONTINUED) DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Listing of Specific Substances Affirmed as GRAS § 184.1165 n-Butane and iso-butane. (a) n-Butane and iso..., odorless, flammable gases at normal temperatures and pressures. They are easily liquefied under pressure at...

Juhtimissüsteemide selgroog. Lean ning ISO - terviklahendused tootmise haldamiseks / Anton Ovsjankin

Index Scriptorium Estoniae

Ovsjankin, Anton

2011-01-01

Kasvanud on juurutatavate Lean ja ISO süsteemide arv, kuid on kasvanud ka nende juurutamise ja arendamisega seotud ebaõnnestumiste arv. Põhjustest, miks jäävad paljud Leani ja ISO juurutanud ettevõtted ilma lubatud tulemusteta. Leani ja ISO haldamiseks vajalikest teguritest

ISO 14000: Review and guidelines for the photovoltaic industry

Energy Technology Data Exchange (ETDEWEB)

DePhillips, M.P.

1997-08-01

The International Organization for Standardization (ISO) has released and is in the process of ratifying a new set of environmental management system standards, ISO 14000. These voluntary international standards will have a significant impact on how companies throughout the international community manage their environmental programs. Initially this impact will result in increased international trade opportunities due to the anticipated customer requirement for suppliers to demonstrate certification. Other potential impacts will benefit both companies engaged in international commerce and companies with a domestic focus. These would include installing a cohesive system to manage environmental matters, participation within a new regulatory paradigm, and adhering to a potentially new set of legal standards. The wide range of potential environmental, commercial, legal and regulatory benefits offered by ISO 14000 offer most companies significant reason to explore the possibilities of implementing an environmental management system. Organizations will be able to anticipate and meet growing environmental expectations and to ensure ongoing compliance with national and international requirements as well as satisfy the growing demands of customers, stakeholders and the interested public. As an emerging industry with significant international ties, the photovoltaic (PV) community will be effected from these standards if they do become globally adopted. In fact some major players in the PV industry have recently received certification to ISO 9000. This again demonstrates a trend within the industry to move toward a uniform system approach to management. This paper will expose interested parties within the PV industry to the details of ISO 14000 and will assist decision makers assess the various possibilities for implementation certification of ISO 14000 for an individual facility.

ISO 9000. Guidelines to increased costs and reduced product quality

International Nuclear Information System (INIS)

Reedy, R.F.

1994-01-01

Many US companies are considering being registered to the provisions of ISO 9000, International Standards for Quality Management. One important problem with the document is that ISO 9000 is not focused on control of product quality. The quality assurance rules established in ISO 9000 have been used in the US for more than 25 years with disastrous financial consequences and little, if any, improvement in quality and safety. These rules are so reliant on documentation and strict compliance that ensuring products comply with specifications has become a secondary issues. That is not what was intended, but it is the result. ISO 9000 program can work effectively only when the top executive responsible for engineering or production takes full responsibility for interpretation and implementation of the quality assurance program. 3 refs., 1 tab

OntoCR: A CEN/ISO-13606 clinical repository based on ontologies.

Science.gov (United States)

Lozano-Rubí, Raimundo; Muñoz Carrero, Adolfo; Serrano Balazote, Pablo; Pastor, Xavier

2016-04-01

To design a new semantically interoperable clinical repository, based on ontologies, conforming to CEN/ISO 13606 standard. The approach followed is to extend OntoCRF, a framework for the development of clinical repositories based on ontologies. The meta-model of OntoCRF has been extended by incorporating an OWL model integrating CEN/ISO 13606, ISO 21090 and SNOMED CT structure. This approach has demonstrated a complete evaluation cycle involving the creation of the meta-model in OWL format, the creation of a simple test application, and the communication of standardized extracts to another organization. Using a CEN/ISO 13606 based system, an indefinite number of archetypes can be merged (and reused) to build new applications. Our approach, based on the use of ontologies, maintains data storage independent of content specification. With this approach, relational technology can be used for storage, maintaining extensibility capabilities. The present work demonstrates that it is possible to build a native CEN/ISO 13606 repository for the storage of clinical data. We have demonstrated semantic interoperability of clinical information using CEN/ISO 13606 extracts. Copyright © 2016 Elsevier Inc. All rights reserved.

75 FR 51996 - Notice of Commission Staff Attendance at Midwest ISO Meetings

Science.gov (United States)

2010-08-24

... Midwest ISO Meetings August 16, 2010. The Federal Energy Regulatory Commission hereby gives notice that members of the Commission and Commission staff may attend the following Midwest ISO-related meetings...., St. Paul, MN) [cir] September 15 [cir] October 20 [cir] November 17 [cir] December 1 Midwest ISO...

ISO celebrates its prolonged life with a video of Jupiter

Science.gov (United States)

1997-07-01

This is excellent news for astronomers and especially for the multinational teams, with leaders in France, Germany, the Netherlands and the United Kingdom, who spent many years devising the four instruments served by ISO's telescope. The camera ISOCAM, the photometer ISOPHOT, the Short Wavelength Spectrometer and the Long Wavelength Spectrometer span between them an unprecedented range of infrared wavelengths from 2 to 200 microns. The atmosphere of Jupiter is one of the cool and cloudy places attracting ISO's attention, and ESA today releases a video of unprecedented images of Jupiter. The planet changes its appearance drastically as the camera ISOCAM scans a range of 90 different infrared wavelengths. Picture by picture, ISOCAM picks out different features of the atmosphere's composition and behaviour. These and other results from ISO will enable scientists to sharpen their ideas about how Jupiter's weather works. "ISO is giving us a new impression of the giant planets of the Solar System," comments Roger Bonnet, ESA's director of science. "Not just Jupiter, but Saturn, Uranus and Neptune too. By observing the planets across its very wide range of infrared wavelengths, ISO can see features overlooked even by spacecraft visiting the planets. The remarkable movie of Jupiter released today represents only a few per cent of ISO's wavelength range, yet every image tells its own story." More information about the Jupiter video appears later in this Information Note. How ISO's cold telescope beat the calendar The need to keep ISO's telescope and instruments chilled to a very low temperature sets a limit to their useful operating life. ISO was supplied with more than 2000 litres of superfluid helium to cool it. Slow evaporation maintains key parts of the spacecraft at temperatures close to absolute zero, below minus 271 degrees C. The rate of loss of helium was expected to be about 3 litres a day, but the cryogenic system could not be tested in exactly the conditions

Comparison of bimodal and bilateral cochlear implant users on speech recognition with competing talker, music perception, affective prosody discrimination, and talker identification.

Science.gov (United States)

Cullington, Helen E; Zeng, Fan-Gang

2011-02-01

Despite excellent performance in speech recognition in quiet, most cochlear implant users have great difficulty with speech recognition in noise, music perception, identifying tone of voice, and discriminating different talkers. This may be partly due to the pitch coding in cochlear implant speech processing. Most current speech processing strategies use only the envelope information; the temporal fine structure is discarded. One way to improve electric pitch perception is to use residual acoustic hearing via a hearing aid on the nonimplanted ear (bimodal hearing). This study aimed to test the hypothesis that bimodal users would perform better than bilateral cochlear implant users on tasks requiring good pitch perception. Four pitch-related tasks were used. 1. Hearing in Noise Test (HINT) sentences spoken by a male talker with a competing female, male, or child talker. 2. Montreal Battery of Evaluation of Amusia. This is a music test with six subtests examining pitch, rhythm and timing perception, and musical memory. 3. Aprosodia Battery. This has five subtests evaluating aspects of affective prosody and recognition of sarcasm. 4. Talker identification using vowels spoken by 10 different talkers (three men, three women, two boys, and two girls). Bilateral cochlear implant users were chosen as the comparison group. Thirteen bimodal and 13 bilateral adult cochlear implant users were recruited; all had good speech perception in quiet. There were no significant differences between the mean scores of the bimodal and bilateral groups on any of the tests, although the bimodal group did perform better than the bilateral group on almost all tests. Performance on the different pitch-related tasks was not correlated, meaning that if a subject performed one task well they would not necessarily perform well on another. The correlation between the bimodal users' hearing threshold levels in the aided ear and their performance on these tasks was weak. Although the bimodal cochlear

Mobile Education: Towards Affective Bi-modal Interaction for Adaptivity

Directory of Open Access Journals (Sweden)

Efthymios Alepis

2009-04-01

Full Text Available One important field where mobile technology can make significant contributions is education. However one criticism in mobile education is that students receive impersonal teaching. Affective computing may give a solution to this problem. In this paper we describe an affective bi-modal educational system for mobile devices. In our research we describe a novel approach of combining information from two modalities namely the keyboard and the microphone through a multi-criteria decision making theory.

Velocity selection for ultra-cold atoms using bimodal mazer cavity

International Nuclear Information System (INIS)

Irshad, A.; Qamar, S.

2009-04-01

In this paper, we discuss the velocity selection of ultra-cold three-level atoms in Λ configuration using a micromazer. Our model is the same as discussed by Arun et al., for mazer action in a bimodal cavity. We have shown that significantly narrowed velocity distribution of ultra-cold atoms can be obtained in this system due to the presence of dark states. (author)

'Bimodal' NTR and LANTR propulsion for human missions to Mars/Phobos

International Nuclear Information System (INIS)

Borowski, Stanley K.; Dudzinski, Leonard A.; McGuire, Melissa L.

1999-01-01

The nuclear thermal rocket (NTR) is one of the leading propulsion options for future human missions to Mars due to its high specific impulse (Isp ∼850-1000 s) and attractive engine thrust-to-weight ratio (∼3-10). Because only a miniscule amount of enriched uranium-235 fuel is consumed in a NTR during the primary propulsion maneuvers of a typical Mars mission, engines configured for both propulsive thrust and modest power generation (referred to as 'bimodal' operation) provide the basis for a robust, 'power-rich' stage enabling propulsive Mars capture and reuse capability. A family of modular 'bimodal' NTR (BNTR) vehicles are described which utilize a common 'core' stage powered by three 66.7 kN (∼15 klbf) BNTRs that produce 50 kWe of total electrical power for crew life support, an active refrigeration/reliquification system for long term, 'zero-boiloff' liquid hydrogen (LH 2 ) storage, and high data rate communications. Compared to other propulsion options, a Mars mission architecture using BNTR transfer vehicles requires fewer transportation system elements which reduces mission mass, cost and risk because of simplified space operations. For difficult Mars options, such as a Phobos rendezvous and sample return mission, volume (not mass) constraints limit the performance of the 'all LH 2 ' BNTR stage. The use of ''LOX-augmented' NTR (LANTR) engines, operating at a modest oxygen-to-hydrogen (O/H) mixture ratio (MR) of 0.5, helps to increase 'bulk' propellant density and total thrust during the trans-Mars injection (TMI) burn. On all subsequent burns, the bimodal LANTR engines operate on LH 2 only (MR=0) to maximize vehicle performance while staying within the mass limits of two ∼80 t 'Magnum' heavy lift launch vehicles (HLLVs)

Authentically radiolabelled Mn(II) complexes as bimodal PET/MR tracers

Energy Technology Data Exchange (ETDEWEB)

Vanasschen, Christian; Brandt, Marie; Ermert, Johannes [Institute of Neuroscience and Medicine, INM-5 - Nuclear Chemistry, Forschungszentrum Jülich (Germany); Neumaier, Bernd [Institute for Radiochemistry and Experimental Molecular Imaging, Medical Clinics, University of Cologne (Germany); Coenen, Heinz H [Institute of Neuroscience and Medicine, INM-5 - Nuclear Chemistry, Forschungszentrum Jülich (Germany)

2015-05-18

The development of small molecule bimodal PET/MR tracers is mainly hampered by the lack of dedicated preparation methods. Authentic radiolabelling of MR contrast agents ensures easy access to such probes: a ligand, chelating a paramagnetic metal ion (e.g. Mn2+) and the corresponding PET isotope (e.g. 52gMn), leads to a “cocktail mixture” where both imaging reporters exhibit the same pharmacokinetics. Paramagnetic [55Mn(CDTA)]2- shows an excellent compromise between thermodynamic stability, kinetic inertness and MR contrast enhancement. Therefore, the aim of this study was to develop new PET/MR tracers by labelling CDTA ligands with paramagnetic manganese and the β+-emitter 52gMn. N.c.a. 52gMn (t1/2: 5.6 d; Eβ+: 575.8 keV (29.6%)) was produced by proton irradiation of a natCr target followed by cation-exchange chromatography. CDTA was radiolabelled with n.c.a. 52gMn2+ in NaOAc buffer (pH 6) at RT. The complex was purified by RP-HPLC and its stability tested in PBS and blood plasma at 37°C. The redox stability was assessed by monitoring the T1 relaxation (20 MHz) in HEPES buffer (pH 7.4). A functionalized CDTA ligand was synthesized in 5 steps. [52gMn(CDTA)]2- was quantitatively formed within 30 min at RT. The complex was stable for at least 6 days in PBS and blood plasma at 37°C and no oxidation occurred within 7 months storage at RT. Labelling CDTA with an isotopic 52g/55Mn2+ mixture led to the corresponding bimodal PET/MR tracer. Furthermore, a functionalized CDTA ligand was synthesized with an overall yield of 18-25%. [52g/55Mn(CDTA)]2-, the first manganese-based bimodal PET/MR tracer prepared, exhibits excellent stability towards decomplexation and oxidation. This makes the functionalized CDTA ligand highly suitable for designing PET/MR tracers with high relaxivity or targeting properties.

Authentically radiolabelled Mn(II) complexes as bimodal PET/MR tracers

International Nuclear Information System (INIS)

Vanasschen, Christian; Brandt, Marie; Ermert, Johannes; Neumaier, Bernd; Coenen, Heinz H

2015-01-01

The development of small molecule bimodal PET/MR tracers is mainly hampered by the lack of dedicated preparation methods. Authentic radiolabelling of MR contrast agents ensures easy access to such probes: a ligand, chelating a paramagnetic metal ion (e.g. Mn2+) and the corresponding PET isotope (e.g. 52gMn), leads to a “cocktail mixture” where both imaging reporters exhibit the same pharmacokinetics. Paramagnetic [55Mn(CDTA)]2- shows an excellent compromise between thermodynamic stability, kinetic inertness and MR contrast enhancement. Therefore, the aim of this study was to develop new PET/MR tracers by labelling CDTA ligands with paramagnetic manganese and the β+-emitter 52gMn. N.c.a. 52gMn (t1/2: 5.6 d; Eβ+: 575.8 keV (29.6%)) was produced by proton irradiation of a natCr target followed by cation-exchange chromatography. CDTA was radiolabelled with n.c.a. 52gMn2+ in NaOAc buffer (pH 6) at RT. The complex was purified by RP-HPLC and its stability tested in PBS and blood plasma at 37°C. The redox stability was assessed by monitoring the T1 relaxation (20 MHz) in HEPES buffer (pH 7.4). A functionalized CDTA ligand was synthesized in 5 steps. [52gMn(CDTA)]2- was quantitatively formed within 30 min at RT. The complex was stable for at least 6 days in PBS and blood plasma at 37°C and no oxidation occurred within 7 months storage at RT. Labelling CDTA with an isotopic 52g/55Mn2+ mixture led to the corresponding bimodal PET/MR tracer. Furthermore, a functionalized CDTA ligand was synthesized with an overall yield of 18-25%. [52g/55Mn(CDTA)]2-, the first manganese-based bimodal PET/MR tracer prepared, exhibits excellent stability towards decomplexation and oxidation. This makes the functionalized CDTA ligand highly suitable for designing PET/MR tracers with high relaxivity or targeting properties.

ISO standardization in nuclear technology

Energy Technology Data Exchange (ETDEWEB)

Brabec, D [Ustav pro Vyzkum, Vyrobu a Vyuziti Radioisotopu, Prague (Czechoslovakia); Cermak, O [Urad pro Normalizaci a Mereni, Prague (Czechoslovakia)

1984-10-01

The activity is described of the technical commission ISO/TC 85 which is currently divided into 4 subcommissions (SC) and 24 working groups. SC 1 ''Terminology, definitions, units, abbreviations'' has one working group. The most important document of this SC is ISO 921-1972 (Dictionary of nuclear technology). SC 2 ''Radiation protection'' has 9 working groups and has processed standards in dosimetry. SC 3 ''Technology of power reactors'' has 6 working groups and its work is related to IAEA activities within the NUSS program. SC 4 ''Technology of nuclear fuels'' has 8 working groups. SC 4 has compiled the basic standards for sealed sources and methods of testing their tightness. The results of the work of this group have been reflected into the standardization work of CMEA. A list is given of published international standards within TC 85.

Pressure-dependent kinetics of initial reactions in iso-octane pyrolysis.

Science.gov (United States)

Ning, HongBo; Gong, ChunMing; Li, ZeRong; Li, XiangYuan

2015-05-07

This study focuses on the studies of the main pressure-dependent reaction types of iso-octane (iso-C8H18) pyrolysis, including initial C-C bond fission of iso-octane, isomerization, and β-scission reactions of the alkyl radicals produced by the C-C bond fission of iso-octane. For the C-C bond fission of iso-octane, the minimum energy potentials are calculated at the CASPT2(2e,2o)/6-31+G(d,p)//CAS(2e,2o)/6-31+G(d,p) level of theory. For the isomerization and the β-scission reactions of the alkyl radicals, the optimization of the geometries and the vibrational frequencies of the reactants, transition states, and products are performed at the B3LYP/CBSB7 level, and their single point energies are calculated by using the composite CBS-QB3 method. Variable reaction coordinate transition state theory (VRC-TST) is used for the high-pressure limit rate constant calculation and Rice-Ramsperger-Kassel-Marcus/master equation (RRKM/ME) is used to calculate the pressure-dependent rate constants of these channels with pressure varying from 0.01-100 atm. The rate constants obtained in this work are in good agreement with those available from literatures. We have updated the rate constants and thermodynamic parameters for species involved in these reactions into a current chemical kinetic mechanism and also have improved the concentration profiles of main products such as C3H6 and C4H6 in the shock tube pyrolysis of iso-octane. The results of this study provide insight into the pyrolysis of iso-octane and will be helpful in the future development of branched paraffin kinetic mechanisms.

Energy management systems in the practice. ISO 50001. A guideline for companies and institutions; Energiemanagementsysteme in der Praxis. ISO 50001. Leitfaden fuer Unternehmen und Organisationen

Energy Technology Data Exchange (ETDEWEB)

Kohlenborn, Walter; Kabisch, Sibylle; Klein, Johanna; Richter, Ina; Schuermann, Silas

2012-06-15

The guideline under consideration is an updated version of the guideline to the regulation EN 16001 and amended to ISO 50001. This contribution supports institutes in the implementation of an energy management system according to ISO 50001. The differences and commonalities to the European environment management system EMAS as well as to the regulation ISO 14001 are described. EMAS certified companies fulfil regularly all conditions of an energy management system. A practised energy management system is an excellent platform for the implementation of EMAS.

76 FR 4104 - Notice of Commission Staff Attendance at Midwest ISO Meetings

Science.gov (United States)

2011-01-24

... Midwest ISO Meetings January 13, 2011. The Federal Energy Regulatory Commission hereby gives notice that members of the Commission and Commission staff may attend the following Midwest ISO-related meetings...] September 14 [cir] October 19 [cir] November 16 [cir] December 6 Midwest ISO Informational Forum (3 p.m.-5 p...

75 FR 3228 - Notice of Commission Staff Attendance at Midwest ISO Meetings

Science.gov (United States)

2010-01-20

... Midwest ISO Meetings January 12, 2010. The Federal Energy Regulatory Commission hereby gives notice that members of the Commission and Commission staff may attend the following Midwest ISO-related meetings...] November 17 [cir] December 1 Midwest ISO Informational Forum (3 p.m.-5 p.m., ET) [cir] January 19 [cir...

KSC Center Director Bridges accepts an ISO 9001 certificate from DNV

Science.gov (United States)

1998-01-01

Center Director Roy Bridges displays the ISO 9001 certificate he was awarded by Det Norske Veritas (DNV), Inc., an international ISO certification organization, at a ceremony at KSC. Dalton Lyon of DNV made the presentation, which included a 2000th ISO Certificate Plaque. ISO 9001 comprises the most detailed, comprehensive set of standard requirements for quality programs established by the International Standards Organization. The presentation followed a successful independent audit by DNV of the KSC Management System in May of this year. The third-party auditors examined about 20 elements of KSC's system, including management responsibility, design control, documentation, test and inspection, and corrective action procedures. DNV found that KSC met or exceeded the stringent quality standards in all areas. KSC will use this certification as a tool to improve an already world-class team. All NASA centers are required by NASA Administrator Daniel S. Goldin to be ISO 9001 registered by September 1999. NASA is the first federal agency to seek the quality certification.

Competence Requirements of ISO/IEC Standards for Information Security Professionals

Directory of Open Access Journals (Sweden)

Natalia G. Miloslavskaya

2017-11-01

Full Text Available The rapid progress in the filed of information security (IS puts one in a need of periodic revision of professional competencies (formulated in the federal state educational standards –FSESs and working functions (formulated in the professional standards – PSs. Under these conditions, a timely reaction to everything new that emerges or will appear in modern regulatory documents (primarily in standards is extremely important. We make a forecast for the content of the ISO/IEC 27021 and ISO/IEC 19896 standards drafted by the International Organization for Standardization (ISO, which should contain the requirements for the competencies of IS management system professionals and the competence of IS testers and evaluators. Our forecast takes into account the requirements of the ISO/IEC 27000 standard group and the recommendations of the European e-Competence Framework e-CF 3.0.

Migración de un SGSI basado en ISO/IEC 27001:2005 a la versión ISO/IEC 27001:2013

OpenAIRE

Espol; Rendón Freire, María José

2015-01-01

Este proyecto tiene como objetivo identificar los cambios en los requisitos de la norma ISO/IEC 27001:2013 respecto a la versión 2005, para lograr la actualización de un sistema de gestión de seguridad de la información basado en ISO/IEC 27001:2005 acorde a lo establecido en el nuevo estándar. Guayaquil Magíster en Seguridad Informática Aplicada

Sifting through the ISO 9000 maze

International Nuclear Information System (INIS)

Abraham, K.S.

1993-01-01

Various forces in the global upstream market are more frequently pressuring equipment and services firms to be certified according to the latest international standards in order to do business. However, understanding and completing the registration process can appear confusing and intimidating at first glance. This paper reviews the ISO's 9000 series of generic standards that provide quality assurance requirements and management guidance. It describes its applicability to the oil and gas industry which often found itself cut out of international markets because they were not recognized as registered ISO participants. It then describes the registration process, evaluation process, and time tables involved. It also describes the difference performance standards of the 9000 series

Influence of age, spatial memory, and ocular fixation on localization of auditory, visual, and bimodal targets by human subjects.

Science.gov (United States)

Dobreva, Marina S; O'Neill, William E; Paige, Gary D

2012-12-01

A common complaint of the elderly is difficulty identifying and localizing auditory and visual sources, particularly in competing background noise. Spatial errors in the elderly may pose challenges and even threats to self and others during everyday activities, such as localizing sounds in a crowded room or driving in traffic. In this study, we investigated the influence of aging, spatial memory, and ocular fixation on the localization of auditory, visual, and combined auditory-visual (bimodal) targets. Head-restrained young and elderly subjects localized targets in a dark, echo-attenuated room using a manual laser pointer. Localization accuracy and precision (repeatability) were quantified for both ongoing and transient (remembered) targets at response delays up to 10 s. Because eye movements bias auditory spatial perception, localization was assessed under target fixation (eyes free, pointer guided by foveal vision) and central fixation (eyes fixed straight ahead, pointer guided by peripheral vision) conditions. Spatial localization across the frontal field in young adults demonstrated (1) horizontal overshoot and vertical undershoot for ongoing auditory targets under target fixation conditions, but near-ideal horizontal localization with central fixation; (2) accurate and precise localization of ongoing visual targets guided by foveal vision under target fixation that degraded when guided by peripheral vision during central fixation; (3) overestimation in horizontal central space (±10°) of remembered auditory, visual, and bimodal targets with increasing response delay. In comparison with young adults, elderly subjects showed (1) worse precision in most paradigms, especially when localizing with peripheral vision under central fixation; (2) greatly impaired vertical localization of auditory and bimodal targets; (3) increased horizontal overshoot in the central field for remembered visual and bimodal targets across response delays; (4) greater vulnerability to

IMPLEMENTING AN ISO 10001-BASED PROMISE IN INPATIENTS CARE

Directory of Open Access Journals (Sweden)

Mohammad Ashiqur Rahman Khan

2013-09-01

Full Text Available This paper presents the implementation of a Customer Satisfaction Promise (CSP that requires nurses to introduce themselves and explain the care plan to the patients of a hospital unit in Canada. The CSP implementation, maintenance and improvement activities were based on ISO 10001:2007. Qualitative and quantitative performance data were collected from nurses, the unit manager and patients, and improvement suggestions were made. During the implementation, nurses introduced themselves 95% of the time and explained the care plan 86% of the time. When interviewed, some nurses stated that the CSP was a good reinforcement of a practice already expected of them, which made patients happy, satisfied and more comfortable. Data from a small sample of patients was not adequate in clearly indicating the CSP's performance or improvement, but was useful in validating the survey and the feedback form. To our knowledge, applications of ISO 10001:2007 in health care have not been studied. Furthermore, this paper may be the first example of the integrated use of ISO 10001 and ISO 10002 in health care.

Towards better GHG emissions savings with use of ISO GHG standards

International Nuclear Information System (INIS)

Chan Kook Weng

2010-01-01

The 15th Conference of Parties (COP 15) at Copenhagen, Denmark in December 2009 highlighted the need to combat climate change by facing the challenge of committing to reducing our emissions at all three levels with locally appropriate mitigation actions (LAMAs) at the local level to be linked to the nationally appropriate mitigation actions (NAMAs) and then contribute onwards to globally appropriate mitigation actions (GAMAs). The aim is to find solutions for both adaptation and mitigation by ensuring sufficient means are made available to support such efforts. This is because the world in entering a new phase that will be characterised by green growth in business. Thus be it agriculture that uses local knowledge of specific crop and livestock varieties to help in secure food supply, bio-energy, transport, industries, there must be policies to understand ecosystem-based to link people, biodiversity, energy, water and carbon so as to be more resilient and adaptable to the need for a low carbon economy in todays society.Climate change therefore affects organisations in many areas and they include legal compliance, carbon market, corporate social responsibility and sustainable development. Promoting sustainability requires making efficient use of energy, water and natural resources, decrease in waste load through recycling and streamlining the processes leading to everything that decreases their CO 2 and water footprints. Currently there are many GHG schemes and programmes and the issues centres around compatibility, costs and most importantly credibility. Achieving real GHG emissions reduction requires controlled and verified emissions reductions and quantification that are sound and verifiable. Thanks to the development of the ISO suite of standards on GHG and related matters, the use of these harmonised standards has given the assurance that a tonne of carbon is a tonne of carbon be it in Malaysia, Mali or Mongolia.The use of these standards like ISO 14064 Part 1

Evaluating Education Quality in Terms of ISO9000 Standards

Science.gov (United States)

Fengchun, Cheng; Vogel, Linda R.; Zhaoyu, Zheng

2014-01-01

While nations measure the quality of educational systems by different standards, many nations, such as China, have adopted the ISO9000 quality standards to assess the quality of schools. This article explores the various elements of the the ISO9000 standards and how each element relates to the various groups that are consumers or stakeholders in…

Establishing an ISO 10001-based promise in inpatients care.

Science.gov (United States)

Khan, Mohammad Ashiqur Rahman; Karapetrovic, Stanislav

2015-01-01

The purpose of this paper is to explore ISO 10001:2007 in planning, designing and developing a customer satisfaction promise (CSP) intended for inpatients care. Through meetings and interviews with research participants, who included a program manager, unit managers and registered nurses, information about potential promises and their implementation was obtained and analyzed. A number of promises were drafted and one was finally selected to be developed as a CSP. Applying the standard required adaptation and novel interpretation. Additionally, ISO 10002:2004 (Clause 7) was used to design the feedback handling activities. A promise initially chosen for development turned out to be difficult to implement, experience that helped in selecting and developing the final promise. Research participants found the ISO 10001-based method useful and comprehensible. This paper presents a specific health care example of how to adapt a standard's guideline in establishing customer promises. The authors show how a promise can be used in alleviating an existing issue (i.e. communication between carers and patients). The learning can be beneficial in various health care settings. To the knowledge, this paper shows the first example of applying ISO 10001:2007 in a health care case. A few activities suggested by the standard are further detailed, and a new activity is introduced. The integrated use of ISO 10001:2007 and 10002:2004 is presented and how one can be "augmented" by the other is demonstrated.

Correspondence of ISO 9001:2008 with IAEA GS-R-3

International Nuclear Information System (INIS)

Kibrit, Eduardo

2009-01-01

This article identifies, characterises and analyses International Organisation for Standardisation (ISO) and International Atomic Energy Agency (IAEA) normative requirements for the development and implementation of quality management systems in nuclear organisations. The structures of the applicable standards, ISO 9001:2008 and IAEA GS-R-3, are characterised. The differences and similarities of objective, focus, scope, level of application, structure, vocabulary, management system, management responsibility, resource management, process implementation, measurement, assessment and improvement verified in the applicable standards are deeply reviewed. A correspondence of the applicable standards' requirements is presented topic by topic. A correlation of the applicable standards' requirements is made, showing IAEA GS-R-3 topics that have no correlation with ISO 9001:2008 and ISO 9001:2008 topics that have no correlation with IAEA GS-R-3. Conclusive remarks advise the pros and cons of using one of the applicable standards or the other. (author)

Bimodality in macroscopic dynamics of nuclear fission

International Nuclear Information System (INIS)

Bastrukov, S.I.; Salamatin, V.S.; Strteltsova, O.I.; Molodtsova, I.V.; Podgainy, D.V.; )

2000-01-01

The elastodynamic collective model of nuclear fission is outlined whose underlying idea is that the stiff structure of nuclear shells imparts to nucleus properties typical of a small piece of an elastic solid. Emphasis is placed on the macroscopic dynamics of nuclear deformations resulting in fission by two energetically different modes. The low-energy S-mode is the fission due to disruption of elongated quadrupole spheroidal shape. The characteristic features of the high-energy T-mode of division by means of torsional shear deformations is the compact scission configuration. Analytic and numerical estimates for the macroscopic fission-barrier heights are presented, followed by discussion of fingerprints of the above dynamical bimodality in the available data [ru

[Approval of ISO/IEC 17025 and quality control of laboratory testing].

Science.gov (United States)

Yamamoto, Shigeki; Asakura, Hiroshi; Machii, Kenji; Igimi, Shizunobu

2010-01-01

First section of Division of Biomedical Food Research, National Institute of Health Sciences (NIHS) was approved by ISO/IEC 17025 as a laboratory having an appropriate laboratory testing technique. NIHS is the first national laboratory approved by ISO/IEC 17025. NIHS has also been accepted the appropriate technique and facility for the BSL3 level pathogens by ISO/IEC 17025. NIHS is necessary to take an external audit almost every year. This approval is renewed every 4 years.

ISO 9000 IMPLEMENTATION AND PERCEIVED ORGANISATIONAL OUTCOME: THE CASE OF A SERVICE ORGANISATION

Directory of Open Access Journals (Sweden)

Jasni Abdul Latif

2003-01-01

Full Text Available The study examines the relationship between the perceptions of the employees about ISO 9000 implementation and perceived organisational outcomes. A conceptual framework linking the level of employee influence and involvement, their perception of ISO 9000 and the perceived impact on their work and the organisational outcomes is posited. Data was collected from a random sample of 64 employees of a service organisation. Contrary to expectations, the work impact of ISO 9000 was not correlated with the efficiency and market outcomes of ISO 9000 certification but the employee involvement, influence and perception of ISO 9000 were. The conceptualization of the influence path of ISO 9000 implementation on the organisational outcomes may require rethinking as perception may have a direct effect on the outcomes without the mediation of the impact on work. In short, employees may report benefits or positive outcomes even though no change is reported in their work.

Time shift in slope failure prediction between unimodal and bimodal modeling approaches

Science.gov (United States)

Ciervo, Fabio; Casini, Francesca; Nicolina Papa, Maria; Medina, Vicente

2016-04-01

Together with the need to use more appropriate mathematical expressions for describing hydro-mechanical soil processes, a challenge issue relates to the need of considering the effects induced by terrain heterogeneities on the physical mechanisms, taking into account the implications of the heterogeneities in affecting time-dependent hydro-mechanical variables, would improve the prediction capacities of models, such as the ones used in early warning systems. The presence of the heterogeneities in partially-saturated slopes results in irregular propagation of the moisture and suction front. To mathematically represent the "dual-implication" generally induced by the heterogeneities in describing the hydraulic terrain behavior, several bimodal hydraulic models have been presented in literature and replaced the conventional sigmoidal/unimodal functions; this presupposes that the scale of the macrostructure is comparable with the local scale (Darcy scale), thus the Richards' model can be assumed adequate to mathematically reproduce the processes. The purpose of this work is to focus on the differences in simulating flow infiltration processes and slope stability conditions originated from preliminary choices of hydraulic models and contextually between different approaches to evaluate the factor of safety (FoS). In particular, the results of two approaches are compared. The first one includes the conventional expression of the FoS under saturated conditions and the widespread used hydraulic model of van Genuchten-Mualem. The second approach includes a generalized FoS equation for infinite-slope model under variably saturated soil conditions (Lu and Godt, 2008) and the bimodal Romano et al.'s (2011) functions to describe the hydraulic response. The extension of the above mentioned approach to the bimodal context is based on an analytical method to assess the effects of the hydraulic properties on soil shear developed integrating a bimodal lognormal hydraulic function

ISO 14000 and the nuclear licensing

International Nuclear Information System (INIS)

Martins, Nadia Soido Falcao

1999-01-01

As concern grows for maintaining and improving the quality of the environment and protecting human health, all the world is turning its attention to the potential environmental in pact of their industrial activities. One of the most important contribution in that way is the International Standard ISO 14000 series. In the utilization of nuclear energy, right from the inception, the safety of personnel, environment and the population has been the basic consideration. Over the years well established licenses criteria have been proposed to limit and control the environmental impact of the plant operation and emergencies situation. In this paper are discussed some specific requirements for implementation of the environmental management system specified by ISO 14000 compared to the environmental requirements for nuclear licensing. (author)

The Bi-Modal Organization: Balancing Autopoiesis and Fluid Social Networks for Sustainability

Science.gov (United States)

Smith, Peter A. C.; Sharicz, Carol Ann

2013-01-01

Purpose: The purpose of this paper is to assist an organization to restructure as a bi-modal organization in order to achieve sustainability in today's highly complex business world. Design/methodology/approach: The paper is conceptual and is based on relevant literature and the authors' research and practice. Findings: Although fluid…

BiBTeX styl pro ČSN ISO 690 a ČSN ISO 690-2

OpenAIRE

Pyšný, Radek

2009-01-01

Tato práce popisuje průběh vytváření bibliografického stylu pro nástroj BibTeX, pomocí něhož lze v LaTeXu sázet bibliografické citace v souladu s normou ČSN ISO 690. V úvodu práce je proveden rozbor ČSN ISO 690. Následuje popis spolupráce mezi systémem LaTeX a nástrojem BibTeX. Podstatná část práce je věnována popisu struktury souborů, které BibTeX potřebuje pro svou funkci, tj. bibliografická databáze a bibliografický styl. Závěr této práce je věnovaný popisu vlastností vytvořeného bibliogra...

The trade-off between heat tolerance and metabolic cost drives the bimodal life strategy at the air-water interface

KAUST Repository

Fusi, Marco; Cannicci, Stefano; Daffonchio, Daniele; Mostert, Bruce; Pö rtner, Hans-Otto; Giomi, Folco

2016-01-01

The principle of oxygen and capacity limitation of thermal tolerance in ectotherms suggests that the long-term upper limits of an organism's thermal niche are equivalent to the upper limits of the organism's functional capacity for oxygen provision to tissues. Air-breathing ectotherms show wider thermal tolerances, since they can take advantage of the higher availability of oxygen in air than in water. Bimodal species move from aquatic to aerial media and switch between habitats in response to environmental variations such as cyclical or anomalous temperature fluctuations. Here we tested the prediction that bimodal species cope better with thermal stress than truly aquatic species using the crab Pachygrapsus marmoratus as a model species. When in water, oxygen consumption rates of P. marmoratus acutely rise during warming. Beyond a temperature threshold of 23 °C the crab's aerobic metabolism in air remains lower than in water. In parallel, the haemolymph oxygen partial pressure of submerged animals progressive decreases during warming, while it remains low but constant during emersion. Our results demonstrate the ability of a bimodal breathing ectotherm to extend its thermal tolerance during air-breathing, suggesting that there are temperature-related physiological benefits during the evolution of the bimodal life style.

The trade-off between heat tolerance and metabolic cost drives the bimodal life strategy at the air-water interface

KAUST Repository

Fusi, Marco

2016-01-13

The principle of oxygen and capacity limitation of thermal tolerance in ectotherms suggests that the long-term upper limits of an organism\\'s thermal niche are equivalent to the upper limits of the organism\\'s functional capacity for oxygen provision to tissues. Air-breathing ectotherms show wider thermal tolerances, since they can take advantage of the higher availability of oxygen in air than in water. Bimodal species move from aquatic to aerial media and switch between habitats in response to environmental variations such as cyclical or anomalous temperature fluctuations. Here we tested the prediction that bimodal species cope better with thermal stress than truly aquatic species using the crab Pachygrapsus marmoratus as a model species. When in water, oxygen consumption rates of P. marmoratus acutely rise during warming. Beyond a temperature threshold of 23 °C the crab\\'s aerobic metabolism in air remains lower than in water. In parallel, the haemolymph oxygen partial pressure of submerged animals progressive decreases during warming, while it remains low but constant during emersion. Our results demonstrate the ability of a bimodal breathing ectotherm to extend its thermal tolerance during air-breathing, suggesting that there are temperature-related physiological benefits during the evolution of the bimodal life style.

Bi-Modal Face and Speech Authentication: a BioLogin Demonstration System

OpenAIRE

Marcel, Sébastien; Mariéthoz, Johnny; Rodriguez, Yann; Cardinaux, Fabien

2006-01-01

This paper presents a bi-modal (face and speech) authentication demonstration system that simulates the login of a user using its face and its voice. This demonstration is called BioLogin. It runs both on Linux and Windows and the Windows version is freely available for download. Bio\\-Login is implemented using an open source machine learning library and its machine vision package.

[ISO 9001-2000 certification for refractive laser treatment].

Science.gov (United States)

Lebuisson, D A; Arson, B; Abenhaïm, A; Albou-Ganem, C; Assouline, M; Chong Sit, D; Danan, A; Montefiore, G; Montin, J-F; Nguyen-Khoa, J-L; Pietrini, D; Saragoussi, J-J; Trong, Th; Amar, R

2005-05-01

To obtain ISO 9001-2000 certification for laser corneal refractive treatment, never before sought in Europe. The consulting firm Veritas led the certification process with the clinic's staff manager. This ISO norm is dedicated to the implementation of a quality management system. We assessed and optimized all necessary resources, evaluating customer satisfaction using patient and referring-physician surveys. We started quality rounds including surgeons, nurses, and technicians. Based on this preparation, we redefined and explained all processes including staff responsibilities and necessary resources in the quality manual. The procedure lasted 14 months with substantial involvement on the part of the management. Unconditional ISO 9001-2000 certification was granted by the independent audit firm, BVQI, in december 2003 for refractive laser treatment. The 2000 version of the new ISO 9001-2000 seeks to meet the demand for improving health care delivery in this field, most particularly by establishing a clear procedural orientation. Such certification enhances team work, stabilizes methodologies, and reinforces cohesion and self-audit. Patients notice that the center follows a consistent quality policy and are assured that the clinic respects rules and regulations. Certification is an advantageous alternative when accreditation cannot be considered. Our article discusses the steps taken in upper management, quality management, procedural guidance, as well as customer and staff counselling. It also discusses the project's cost/benefit ratio for the organization.

Bimodal MR-PET agent for quantitative pH imaging

Science.gov (United States)

Frullano, Luca; Catana, Ciprian; Benner, Thomas; Sherry, A. Dean; Caravan, Peter

2010-01-01

Activatable or “smart” magnetic resonance contrast agents have relaxivities that depend on environmental factors such as pH or enzymatic activity, but the MR signal depends on relaxivity and agent concentration – two unknowns. A bimodal approach, incorporating a positron emitter, solves this problem. Simultaneous positron emission tomography (PET) and MR imaging with the biomodal, pH-responsive MR-PET agent GdDOTA-4AMP-F allows direct determination of both concentration (PET) and T1 (MRI), and hence pH. PMID:20191650

Framework for establishing records control in hospitals as an ISO 9001 requirement.

Science.gov (United States)

Al-Qatawneh, Lina

2017-02-13

Purpose The purpose of this paper is to present the process followed to control records in a Jordanian private community hospital as an ISO 9001:2008 standard requirement. Design/methodology/approach Under the hospital quality council's supervision, the quality management and development office staff were responsible for designing, planning and implementing the quality management system (QMS) using the ISO 9001:2008 standard. A policy for records control was established. An action plan for establishing the records control was developed and implemented. On completion, a coding system for records was specified to be used by hospital staff. Finally, an internal audit was performed to verify conformity to the ISO 9001:2008 standard requirements. Findings Successful certification by a neutral body ascertained that the hospital's QMS conformed to the ISO 9001:2008 requirements. A framework was developed that describes the records controlling process, which can be used by staff in any healthcare organization wanting to achieve ISO 9001:2008 accreditation. Originality/value Given the increased interest among healthcare organizations to achieve the ISO 9001 certification, the proposed framework for establishing records control is developed and is expected to be a valuable management tool to improve and sustain healthcare quality.

Vocational High School Effectiveness Standard ISO 9001: 2008 for Achievement Content Standards, Standard Process and Competency Standards Graduates

Directory of Open Access Journals (Sweden)

Yeni Ratih Pratiwi

2014-06-01

Full Text Available Efektivitas Sekolah Menengah Kejuruan Berstandar ISO 9001:2008 terhadap Pencapaian Standar Isi, Standar Proses dan Standar Kompetensi Lulusan Abstract: The purpose of this study was to determine differences in the effectiveness of the achievement of the content standards, process standards, and competency standards in vocational already standard ISO 9001: 2008 with CMS that has not been standardized ISO 9001: 2008 both in public schools and private schools. Data collection using the questionnaire enclosed Likert scale models. Analysis of data using one-way ANOVA using SPSS. The results showed: (1 there is no difference in effectiveness between public SMK ISO standard ISO standards with private SMK (P = 0.001; (2 there are differences in the effectiveness of public SMK SMK ISO standards with ISO standards have not (P = 0.000; (3 there are differences in the effectiveness of public SMK ISO standards with private vocational yet ISO standards (P = 0.000; (4 there are differences in the effectiveness of the private vocational school with vocational standard ISO standard ISO country has not (P = 0.015; (5 there are differences in the effectiveness of the private vocational bertandar ISO with private vocational yet standardized ISO (P = 0.000; (6 there was no difference in the effectiveness of public SMK has not been standardized by the ISO standard ISO private SMK yet. Key Words: vocational high school standards ISO 9001: 2008, the standard content, process standards, competency standards Abstrak: Tujuan penelitian ini untuk mengetahui perbedaan efektivitas pencapaian standar isi, standar proses, dan standar kompetensi lulusan pada SMK yang sudah berstandar ISO 9001:2008 dengan SMK yang belum berstandar ISO 9001:2008 baik pada sekolah negeri maupun sekolah swasta. Pengumpulan data menggunakan kuisioner tertutup model skala likert. Analisis data menggunakan ANOVA one way menggunakan program SPSS. Hasil penelitian menunjukkan: (1 ada perbedaan

Analysis of ISO 26262 Compliant Techniques for the Automotive Domain

NARCIS (Netherlands)

M. S. Kannan; Y. Dajsuren (Yanjindulam); Y. Luo; I. Barosan

2015-01-01

htmlabstractThe ISO 26262 standard denes functional safety for automotive E/E systems. Since the publication of the rst edition of this standard in 2011, many dierent safety techniques complying to the ISO 26262 have been developed. However, it is not clear which parts and (sub-) phases of the

Analysis of ISO 26262 compliant techniques for the automotive domain

NARCIS (Netherlands)

S., Manoj Kannan; Dajsuren, Y.; Luo, Y.; Barosan, I.; Antkiewicz, M.; Atlee, J.; Dingel, J.; S, R.

2015-01-01

The ISO 26262 standard defines functional safety for automotive E/E systems. Since the publication of the first edition of this standard in 2011, many different safety techniques complying to the ISO 26262 have been developed. However, it is not clear which parts and (sub-) phases of the standard

Diagnóstico da integração dos sistemas de gestão ISO 9001, ISO 14001 e OHSAS 18001

Directory of Open Access Journals (Sweden)

Samuel Vinícius Bonato

2015-09-01

Full Text Available Este artigo apresenta os resultados de uma pesquisa que teve por finalidade o diagnóstico do nível de integração de sistemas de gestão baseados nas normas ISO 9001, ISO 14001 e OHSAS 18001 em empresas do ramo metal-mecânico. Inicialmente foi descrito o método de diagnóstico e posteriormente realizada a sua aplicação em uma empresa já certificada nas três normas, mas que possui dois sistemas de gestão distintos: o Sistema de Gestão da Qualidade (SGQ baseado na norma ISO 9001 e o Sistema de Gestão de Saúde, Segurança e Meio Ambiente (SSM baseado nas normas ISO 14001 e OHSAS 18001. Entre os principais resultados, destaca-se a aceitação favorável do diagnóstico da integração na empresa estudada. Com a realização do diagnóstico, verificou-se que a organização não atende totalmente a integração de nenhum dos requisitos avaliados. Foram sugeridas oportunidades de melhoria para integração dos requisitos normativos comuns, reduzindo custos e recursos para manutenção do sistema de gestão da empresa.

Discussion on the compilation of document of iso quality management system for radiation sterilization enterprises

International Nuclear Information System (INIS)

Li Chunhong; Ha Yiming; Zhou Hongjie; Feng Zhiguo; Wang Feng

2006-01-01

According to the character of cooperation of radiation sterilization, and association with request of ISO9001, ISO13485 and ISO11137, compilation of document in quality manual, procedure document and technological document during certification of ISO quality management system of cooperation of radiation sterilization was discussed. (authors)

Processing bimodal stimulus information under alcohol: is there a risk to being redundant?

Science.gov (United States)

Fillmore, Mark T

2010-10-01

The impairing effects of alcohol are especially pronounced in environments that involve dividing attention across two or more stimuli. However, studies in cognitive psychology have identified circumstances in which the presentation of multiple stimuli can actually facilitate performance. The "redundant signal effect" (RSE) refers to the observation that individuals respond more quickly when information is presented as redundant, bimodal stimuli (e.g., aurally and visually), rather than as a single stimulus presented to either modality alone. The present study tested the hypothesis that the response facilitation attributed to RSE could reduce the degree to which alcohol slows information processing. Two experiments are reported. Experiment 1 demonstrated the validity of a reaction time model of RSE by showing that adults (N = 15) responded more quickly to redundant, bimodal stimuli (visual + aural) versus either stimuli presented individually. Experiment 2 used the RSE model to test the reaction time performance of 20 adults following three alcohol doses (0.0 g/kg, 0.45 g/kg, and 0.65 g/kg). Results showed that alcohol slowed reaction time in a general dose-dependent manner in all three stimulus conditions with the reaction time (RT) speed-advantage of the redundant signal being maintained, even under the highest dose of alcohol. Evidence for an RT advantage to bimodal stimuli under alcohol challenges the general assumption that alcohol impairment is intensified in multistimulus environments. The current study provides a useful model to investigate how drug effects on behavior might be altered in contexts that involve redundant response signals.

Interim Report on ISO TC 163 Working Group 3. Annual progress report

Energy Technology Data Exchange (ETDEWEB)

Fairey, Philip [Florida Solar Energy Center, Cocoa, FL (United States)

2009-04-02

This reports cover the initial year efforts of the International Standards Organization (ISO) to develop international standards for rating the energy performance of buildings. The author of this report is a participant in this effort. This report summarizes the activities of the ISO Working Group charged with development of these standards and makes recommendations to the sponsors for future U.S. involvement in this ISO effort.

Progress report on the management of the NEA ISOE system

Energy Technology Data Exchange (ETDEWEB)

Lazo, E. [OECD Nuclear Energy Agency, Issy-les-Moulineaux (France)

1995-03-01

The Information System on Occupational Exposure (ISOE) was launched by the Organization for Economic Cooperation and Development (OECD), Nuclear Energy Agency (NEA) on 1 January, 1992, to facilitate the communication of dosimetric and ALARA implementation data among nuclear utilities around the world. After two years of operation the System has become a mature interactive network for transfer of data and experience. Currently, 37 utilities from 12 countries, representing 289 power plants, and 12 national regulatory authorities participate in ISOE. Agreements for cooperation also exist between the NEA and the Commission of the European Communities (CEC), and the Paris Center of the WOrld Association of Nuclear Operators (WANO-PC). In addition, the International Atomic Energy Agency (IAEA) is acting as a co-sponsor of ISOE for the participation of non-NEA member countries. Three Regional Technical Centres, Europe, Asia, and Non-NEA member countries, serve to administer the system. The ISOE Network is comprised of three data bases and a communications network at several levels. The three ISOE data bases include the following types of information: NEA1 - annual plant dosimetric information; NEA2 - plant operational characteristics for dose and dose rate reduction; and NEA3 - job specific ALARA practices and experiences. The ISOE communications network has matured greatly during 1992 and 1993. In addition to having access to the above mentioned data bases, participants may now solicit information on new subjects, through the Technical Centres, from all other participants on a real-time basis. Information Sheets on these studies are produced for distribution to all participants. In addition, Topical Reports on areas of interest are produced, and Topical Meetings are held annually.

Progress report on the management of the NEA ISOE system

International Nuclear Information System (INIS)

Lazo, E.

1995-01-01

The Information System on Occupational Exposure (ISOE) was launched by the Organization for Economic Cooperation and Development (OECD), Nuclear Energy Agency (NEA) on 1 January, 1992, to facilitate the communication of dosimetric and ALARA implementation data among nuclear utilities around the world. After two years of operation the System has become a mature interactive network for transfer of data and experience. Currently, 37 utilities from 12 countries, representing 289 power plants, and 12 national regulatory authorities participate in ISOE. Agreements for cooperation also exist between the NEA and the Commission of the European Communities (CEC), and the Paris Center of the WOrld Association of Nuclear Operators (WANO-PC). In addition, the International Atomic Energy Agency (IAEA) is acting as a co-sponsor of ISOE for the participation of non-NEA member countries. Three Regional Technical Centres, Europe, Asia, and Non-NEA member countries, serve to administer the system. The ISOE Network is comprised of three data bases and a communications network at several levels. The three ISOE data bases include the following types of information: NEA1 - annual plant dosimetric information; NEA2 - plant operational characteristics for dose and dose rate reduction; and NEA3 - job specific ALARA practices and experiences. The ISOE communications network has matured greatly during 1992 and 1993. In addition to having access to the above mentioned data bases, participants may now solicit information on new subjects, through the Technical Centres, from all other participants on a real-time basis. Information Sheets on these studies are produced for distribution to all participants. In addition, Topical Reports on areas of interest are produced, and Topical Meetings are held annually

ISO standardization in nuclear technology

Energy Technology Data Exchange (ETDEWEB)

Brabec, D. (Ustav pro Vyzkum, Vyrobu a Vyuziti Radioisotopu, Prague (Czechoslovakia)); Cermak, O. (Urad pro Normalizaci a Mereni, Prague (Czechoslovakia))

1984-10-01

The activity is described of the technical commission ISO/TC 85 which is currently divided into 4 subcommissions (SC) and 24 working groups. SC 1 ''Terminology, definitions, units, abbreviations'' has one working group. The most important document of this SC is ISO 921-1972 (Dictionary of nuclear technology). SC 2 ''Radiation protection'' has 9 working groups and has processed standards in dosimetry. SC 3 ''Technology of power reactors'' has 6 working groups and its work is related to IAEA activities within the NUSS program. SC 4 ''Technology of nuclear fuels'' has 8 working groups. SC 4 has compiled the basic standards for sealed sources and methods of testing their tightness. The results of the work of this group have been reflected into the standardization work of CMEA. A list is given of published international standards within TC 85.

IMPLEMENTASI ISO 9001: 2000 PADA PEMBELAJARAN PRODUKTIF BIDANG KEAHLIAN BANGUNAN DI SEKOLAH MENENGAH KEJURUAN

Directory of Open Access Journals (Sweden)

Riban Riban

2012-08-01

Full Text Available The implementation of ISO 9001: 2000 in productive learning of building engineering sector in vocational education. The objtective of this study was to uncover the barriers to implementation of ISO 9001:2000 in productive learning. The study was designed using multisite study design. Tecniques of collecting the data were interview, observation to partici­pants, and documentation test. The result of the study are: (1 Implementation of the ISO 9001: 2000 in productive learning of  building engineering sector relates to the implementation of the concept of P-D-C-A in the ISO quality management system; (2 the barriers in implementation of ISO 9001:2000 in pro­ductive learning include low awareness level, inconsistencies, and disobedience; and (3 efforts to overcome the barriers to implementation of ISO 9001:2000 in produc­tive learning involve building the shared commitment, socialization in order to create together awareness, supervising, and doing the preventive action. Implementasi ISO 9001: 2000 pada Pembelajaran Produktif Bidang Keahlian Bangunan di Sekolah Menengah Kejuruan. Penelitian ini bermaksud meng­ungkap lebih mendalam tentang, imple­men­­­tasi, hambatan-hambatan, dan upaya-upaya dalam mengatasi ham­batan penerap­an ISO 9001: 2000 pada pembelajaran produktif. Penelitian ini diran­cang dengan menggunakan rancangan studi multisitus. Teknik pengum­pulan data meliputi wawan­cara, observasi partisipan, dan studi dokumentasi. Temuan penelitian adalah: (1 Penerapan ISO 9001: 2000 pada pem­belajaran pro­duktif teknik bangunan mengacu pada konsep P-D-C-A ke dalam sistem manajemen mutu ISO; (2 hambatan implementasi ISO 9001: 2000 pada pem­bel­ajaran produktif meliputi tingkat kesadaran rendah, inkonsistensi, dan ketidak­taatasasan; dan (3 upaya mengatasi hambatan dalam implementasi ISO 9001: 2000 pada pembelajar­an produk­tif meliputi membangun komitmen bersama, sosialisasi dalam rangka me­num­buhkan kesadaran bersama

ISO 26000 – An Integrative Approach of Corporate Social Responsibility

Directory of Open Access Journals (Sweden)

Herciu Mihaela

2016-04-01

Full Text Available ISO 26000 represents a guidance on corporate social responsibility and it is, at the present time, one of the most important document on CSR in the world. Without being mandatory or regulated, ISO 26000 is focus on seven core subjects that have to be approached synergistic – governance, human right, labor, environment, business practices, consumer, and community – in order to achieve its goal. The present paper intends to present and analyze the seven core subjects of ISO 26000 from tow perspectives: by emphasizing the benefits of implementing the standard into the business strategy and by revealing the correlation between corporate social responsibility and sustainable development.

The Taylor-expansion method of moments for the particle system with bimodal distribution

Directory of Open Access Journals (Sweden)

Liu Yan-Hua

2013-01-01

Full Text Available This paper derives the multipoint Taylor expansion method of moments for the bimodal particle system. The collision effects are modeled by the internal and external coagulation terms. Simple theory and numerical tests are performed to prove the effect of the current model.

Age, colors and ISO standards

NARCIS (Netherlands)

Nes, van F.L.; Eschbach, R; Marcu, G.G.; Tominaga, S.; Rizzi, A.

2010-01-01

Age influences all bodily functions, also vision. Therefore, the effects of age on vision should be mirrored in ergonomic requirements laid down in display standards such as ISO 9241-300/307, 'Electronic visual display requirements'. However, this is only true to a limited extent - just as is the

ISO 14001: time for improvements?

DEFF Research Database (Denmark)

Jørgensen, Tine Herreborg

2007-01-01

The aim of this paper is to discuss a number of issues related to ISO 14001:2004, the international standard for Environmental Management Systems (EMS) with the purpose of improving the next edition in order to recognise and reflect new recognitions in approaches to pollution prevention. A case...

Specification of Energy Assessment Methodologies to Satisfy ISO 50001 Energy Management Standard

Science.gov (United States)

Kanneganti, Harish

Energy management has become more crucial for industrial sector as a way to lower their cost of production and in reducing their carbon footprint. Environmental regulations also force the industrial sector to increase the efficiency of their energy usage. Hence industrial sector started relying on energy management consultancies for improvements in energy efficiency. With the development of ISO 50001 standard, the entire energy management took a new dimension involving top level management and getting their commitment on energy efficiency. One of the key requirements of ISO 50001 is to demonstrate continual improvement in their (industry) energy efficiency. The major aim of this work is to develop an energy assessment methodology and reporting format to tailor the needs of ISO 50001. The developed methodology integrates the energy reduction aspect of an energy assessment with the requirements of sections 4.4.3 (Energy Review) to 4.4.6 (Objectives, Targets and Action Plans) in ISO 50001 and thus helping the facilities in easy implementation of ISO 50001.

Implementation of ISO 10110 optics drawing standards for the National Ignition Facility

International Nuclear Information System (INIS)

Aikens, D. M.; English, R. E.; Wang, D. Y.

1999-01-01

The National Ignition Facility (NIF) project elected to implement ISO 10110 standard for the specifications of NIF optics drawings in 1996. More than 7,000 NIF large optics and 20,000 NIF small optics will be manufactured based on ISO 10110 indications. ISO 10110 standard meets many of the needs of the NIF optics specifications. It allows the optical engineer to quantify and clearly communicate the desired optical specifications. While no single drawing standard specifies all the requirements of high energy laser system, a combination of ISO 10110 standard with detailed notes make it possible to apply international drawing standards to the NIF laser system. This paper will briefly describe LLNL's interpretation and implementation of the ISO 10110 drawing standard, present some examples of NIF optics drawings, and discuss pros and cons of the indications from the perspective of this application. Emphasis will be given to the surface imperfection specifications, known as 5/, for the NIF optics

Implementation of ISO 10110 optics drawing standards for the National Ignition Facility

Science.gov (United States)

Wang, David Y.; English, R. Edward, Jr.; Aikens, David M.

1999-11-01

The National Ignition Facility (NIF) project elected to implement ISO 10110 standard for the specifications of NIF optics drawings in 1996. More than 7,000 NIF large optics and 20,000 NIF small optics will be manufactured based on ISO 10110 indications. ISO 10110 standard meets many of the needs of the NIF optics specifications. It allows the optical engineer to quantify and clearly communicate the desired optical specifications. While no single drawing standard specifies all the requirements of high energy laser system, a combination of ISO 10110 standard with detailed notes make it possible to apply international drawing standards to the NIF laser system. This paper will briefly describe LLNL's interpretation and implementation of the ISO 10110 drawing standard, present some examples of NIF optics drawings, and discuss pros and cons of the indications from the perspective of this application. Emphasis will be given to the surface imperfection specifications, known as 5/, for the NIF optics.

Plasma 8-iso-Prostaglandin F2α, a possible prognostic marker in aneurysmal subarachnoid hemorrhage.

Science.gov (United States)

Pan, De-Sheng; Yan, Min; Hassan, Muhammad; Fang, Ze-Bin; Chen, Man-Tao

2017-06-01

8-iso-Prostaglandin F2α (8-iso-PGF2α) is a potential biomarker of oxidative stress. This study clarified whether plasma 8-iso-PGF2α concentrations were affected and its underlying relevance to prognosis in aneurysmal subarachnoid hemorrhage (aSAH). In this prospective, observational study, a total of 170 controls and 170 aSAH patients were enrolled. Plasma 8-iso-PGF2α concentrations were detected using an ELISA. Severity was assessed by World Federation of Neurological Surgeons (WFNS) scale and modified Fisher grading scale. Clinical outcomes included 6-month mortality and poor outcome referred to as Glasgow outcome scale score of 1-3. As compared to controls, admission plasma 8-iso-PGF2α concentrations were significantly enhanced. Increased concentrations of plasma 8-iso-PGF2α correlated with WFNS scores and modified Fisher scores. 8-iso-PGF2α in plasma was an independent predictor for clinical outcomes. Under ROC curve, the predictive values of 8-iso-PGF2α concentrations resembled those of WFNS scores and modified Fisher scores for clinical outcomes. An elevation in plasma 8-iso-PGF2α concentrations is associated with the severity and poor outcome after aSAH, substantializing 8-iso-PGF2α as a potential prognostic biomarker of aSAH. Copyright © 2017. Published by Elsevier B.V.

75 FR 5779 - Notice Providing Agenda for Technical Conference on RTO/ISO Responsiveness

Science.gov (United States)

2010-02-04

... Conference on RTO/ISO Responsiveness January 27, 2010. California Independent System Operator Docket No. ER09.... Southwest Power Pool, Inc Docket Nos. ER09-1050-000, ER09- 1192-000. ISO New England, Inc. and New England.... Agenda--Technical Conference on RTO/ISO Responsiveness February 4, 2010 12:30 Panel 1--Stakeholder...

ISO 9000 Series Certification Over Time: what have we learnt?

NARCIS (Netherlands)

A. van der Wiele (Ton); A.M. Brown (Alan)

2002-01-01

textabstractThe ISO 9000 experiences of the same sample of organisations over a five year time period is examined in this paper. The responses to a questionnaire sent out at the end of 1999 to companies which had a reasonably long term experience with the ISO 9000 series quality system are analysed.

Quality standards: Comparison between IAEA 50-C/SG-Q and ISO 9001:2000

International Nuclear Information System (INIS)

2002-01-01

The International Atomic Energy Agency (IAEA) has the statutory mandate to seek to accelerate and enlarge the contribution of atomic energy to peace, health and prosperity throughout the world. As part of the activities to achieve its objectives, the IAEA is authorized to establish standards of safety for the protection of health and the minimization of danger to life and property. The standards of safety developed by the IAEA are recommendations for use by its Member States in the framework of national regulations for the safe utilization of nuclear energy. Such standards should be considered as nuclear safety regulatory documents. The standards developed by the International Organization for Standardization (ISO) are complementary technical documents emphasizing industrial application and contractual aspects. Regarding the quality assurance topic, the IAEA developed the publication Safety Series No. 50-C/SG-Q, Quality Assurance for Safety in Nuclear Power Plants and other Nuclear Installations, which is mostly used directly or indirectly to establish the nuclear safety requirements at the nuclear utility-regulator interface. The ISO 9001:2000 standard, Quality Management Systems Requirements, is often used to define the quality management system requirements at the utility-supplier interface. The relationship between the IAEA and ISO quality standards is growing in significance owing to their increasing impact upon utilities (owners/operators of nuclear facilities) and their contractors/suppliers. The relationship between the IAEA and ISO standards is considered critical in particular with respect to contractors/suppliers with a small range of nuclear supplies. These contractors-suppliers are not always willing to prepare special quality assurance programmes based on nuclear safety standards. On the other hand, these contractors/suppliers may be qualified on the basis of the ISO quality standard. In any case, for delivering nuclear items and services the

ISO 14001: implementar ou não? Uma proposta para a tomada de decisão ISO 14001: adopt it or not? A proposal for the decision making process

Directory of Open Access Journals (Sweden)

Giuliano Nacarato Moretti

2008-12-01

Full Text Available Entre as vantagens e desvantagens oferecidas pela implementação da norma ISO 14001, o empresário, muitas vezes, não encontra subsídios suficientes para a tomada de decisão pela adoção ou não da referida norma. Este trabalho apresenta uma ferramenta de auxílio à tomada de decisão empresarial, promovendo um estudo sobre a real necessidade e viabilidade da implementação da norma ISO 14001 e a respectiva certificação. Trata-se de uma análise multicriterial, em que se verifica a compatibilidade entre o perfil organizacional e a norma ISO 14001. Busca-se facilitar a decisão das organizações em adotar ou não a ISO 14001, por meio de uma recomendação que aumente sua probabilidade de atingir os objetivos almejados. A ferramenta demonstrou sua forte aplicabilidade quando implementada em duas empresas.One of the difficulties of the decision making process, is that many entrepreneurs may find themselves incapable of finding enough subsidies for the decision of adopting or not the ISO 14001 standard. This work presents a tool that facilitates corporate decision making, providing a thorough analysis of the real necessity and feasibility of the implementation of the ISO 14001 standard and its certification. This tool consists of a multicriterial analysis, in which is possible to verify the compatibility between the organizational profile and the ISO 14001 standard. This recommendation of adopting or not the ISO 14001 standard seeks to facilitate the organization decision making; and, as a result, it also enhances the probability of the organization attaining its objectives. This tool presented a strong applicability when implemented in two companies.

PERBANDINGAN IMPLEMENTASI ISO DAN PELUNCURAN ENTERPRISE RESOURCES PLANNING TERHADAP INDEKS KINERJA KEUANGAN

Directory of Open Access Journals (Sweden)

Sautma Ronni Basana

2017-03-01

Full Text Available Recently, companies implemented projects which applied on companies’ overall system. These recent bestpractices of pursuing companies’ effectiveness and efficiency would be implementation of ISO 9000 and ERP.Previous research showed that these two projects could bring benefits for these companies which implementedit. However, it had not been compared which project would bring more benefits to these companies. Thisresearch observed 35 companies which consisted of 15 companies in food and beverages industry, 9 companiesin pharmaceutical industry, 4 companies in cigarettes industry, 4 companies in cosmetics industry, and 3companies in household appliances industry. The data were taken by observing and recording the valueswhich related to COGS (cost of goods sold, total inventory, net income, gross income, operating income, pretaxincome, cash flow operation, total liabilities, and total asset after ISO and ERP implementation. The resultsshowed that there was no significant difference of the ISO and ERP implementation on the factors of inventoryturnover, and weeks of supply. While the other factors showed significant differences between the implementationof ERP and ISO. Net profit margin, gross profit margin, and operating profit margin showed better resulton ERP launching. On the other hand, pretax margin showed better than ISO 9000 implementation. Overall,ERP implementation showed better results compared with ISO 9000.

Iso-vector form factors of the delta and nucleon in QCD sum rules

International Nuclear Information System (INIS)

Ozpineci, A.

2012-01-01

Form factors are important non-perturbative properties of hadrons. They give information about the internal structure of the hadrons. In this work, iso-vector axial-vector and iso-vector tensor form factors of the nucleon and the iso-vector axial-vector Δ→N transition form factor calculations in QCD Sum Rules are presented.

As Escalas Geográficas da Certificação ISO 14001: um panorama da gestão ambiental empresarial

Directory of Open Access Journals (Sweden)

Henrique Elias Pessoa Gutierres

2013-06-01

Full Text Available Environmental certification, especially ISO 14001, demonstrates the existence of internal and external factors for improving the environmental performance of companies. Thus, this article aims to present a current overview of ISO 14001 certification at different scales of analysis (global, national, regional and state, seeking its territoriality by considering factors of location, extent and connection. The following procedures were adopted: a survey of the theoretical reference, the acquisition of data from the ISO (International Organization for Standardization and INMETRO (National Institute of Metrology, Standardization and Industrial Quality on the quantity of companies certified by ISO 14001. After organizing the data, there was systematization through tables via spreadsheet, presentation and finalization of graphs and data analysis relating to the Human Development Index (HDI and Gross Domestic Product (GDP. It is understood that most of these certificates is concentrated in developed countries, where the headquarters of large companies are located. Considering the Brazilian reality, the ratio (number of certifications, GDP and HDI by state was not so obvious, since there are states with lower GDP and HDI, but with higher certificates compared to some states that are better positioned socio-economically. This feature has to do with economic aspects of the companies that have a strong influence on the occurrence of these certificates. Therefore, we present a spatially uneven reality where the environmental certification is not always related to the local reality, being a requirement of external factors, such as a continuing relation with customers and suppliers who hold environmental certification. Therefore, it is something external acting in local reality.

A search for PAHs in the ISO spectra of comet Hale-Bopp

Science.gov (United States)

Crovisier, J.; Bockelée-Morvan, D.

2007-12-01

From a new analysis of a spectrum of comet C/1995 O1 (Hale-Bopp) obtained with the Infrared Space Observatory (ISO), Lisse et al. (2007) claimed the identification of many new dust species. Among them are PAHs, which were not found in our first analysis of the ISO spectra. We present a re-examination of the ISO observations of comet Hale-Bopp, which does not confirm the conclusion of Lisse et al.

U-value measurements on ISO round Robin window

DEFF Research Database (Denmark)

Duer, Karsten

1997-01-01

9 laboratories in 6 european and 2 north american countries have participated in a round robin U-value test of a standard facade window. The objective of the round robin test was to verify that the ISO/CEN proposals for U-value measurement standard is robust.......9 laboratories in 6 european and 2 north american countries have participated in a round robin U-value test of a standard facade window. The objective of the round robin test was to verify that the ISO/CEN proposals for U-value measurement standard is robust....

The new ISO 6579-1: A real horizontal standard for detection of Salmonella, at last!

Science.gov (United States)

Mooijman, Kirsten A

2018-05-01

Up to 2016, three international standard methods existed for the detection of Salmonella spp. in food, animal feed and samples from the primary production stage: ISO 6785:2001 for milk and milk products, ISO 6579:2002 for (other) food and animal feed and Annex D of ISO 6579:2007 for samples from the primary production stage. In 2009, an ISO/CEN working group started with the revision of ISO 6579:2002 with two main aims: combining the three aforementioned standards in one document and improving the information in ISO 6579:2002. Additionally it was decided to split ISO 6579 into three parts, where part 1 describes the detection, part 2 the enumeration by mini-MPN (published in 2012) and part 3 the serotyping of Salmonella (published in 2014). This paper describes the experiments and choices made for improving the part on detection of Salmonella (ISO 6579-1). The final voting stage on (draft) ISO 6579-1 was finished by the end of December 2016, with a positive outcome. Finally, a real horizontal standard became available for detection of Salmonella in food, animal feed, environmental samples in the area of food production and food handling and in samples from the primary production stage in 2017. Copyright © 2017 Elsevier Ltd. All rights reserved.

α-Iso-cubebene exerts neuroprotective effects in amyloid beta stimulated microglia activation.

Science.gov (United States)

Park, Sun Young; Park, Se Jin; Park, Nan Jeong; Joo, Woo Hong; Lee, Sang-Joon; Choi, Young-Whan

2013-10-25

Schisandra chinensis is commonly used for food and as a traditional remedy for the treatment of neuronal disorders. However, it is unclear which component of S. chinensis is responsible for its neuropharmacological effects. To answer this question, we isolated α-iso-cubebene, a dibenzocyclooctadiene lignin, from S. chinensis and determined if it has any anti-neuroinflammatory and neuroprotective properties against amyloid β-induced neuroinflammation in microglia. Microglia that are stimulated by amyloid β increased their production of pro-inflammatory cytokines and chemokines, prostaglandin E2 (PGE2), nitric oxide (NO) and reactive oxygen species (ROS) and the enzymatic activity of matrix metalloproteinase 9 (MMP-9). We found this was all inhibited by α-iso-cubebene. Consistent with these results, α-iso-cubebene inhibited the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase 2 (COX-2) and MMP-9 in amyloid β-stimulated microglia. Subsequent mechanistic studies revealed that α-iso-cubebene inhibited the phosphorylation and degradation of IκB-α, the phosphorylation and transactivity of NF-κB, and the phosphorylation of MAPK in amyloid β-stimulated microglia. These results suggest that α-iso-cubebene impairs the amyloid β-induced neuroinflammatory response of microglia by inhibiting the NF-κB and MAPK signaling pathways. Importantly, α-iso-cubebene can provide critical neuroprotection for primary cortical neurons against amyloid β-stimulated microglia-mediated neurotoxicity. To the best of our knowledge, this is the first report showing that α-iso-cubebene can provide neuroprotection against, and influence neuroinflammation triggered by, amyloid β activation of microglia. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

ISO sertifikaat aitab otsustada / Toomas Udu

Index Scriptorium Estoniae

Udu, Toomas

2005-01-01

Ilmunud ka: Delovõje Vedomosti : Transport i logistika 25. mai lk. 8. Teenuse kvaliteedi näitajad logistikafirmas ISO standardi alusel. Vt. samas: Eestis kasutatakse kolme kvaliteedistandardit; Kuidas mõjutada kvaliteeti läbi juhtimissüsteemi

Contralateral Bimodal Stimulation: A Way to Enhance Speech Performance in Arabic-Speaking Cochlear Implant Patients.

Science.gov (United States)

Abdeltawwab, Mohamed M; Khater, Ahmed; El-Anwar, Mohammad W

2016-01-01

The combination of acoustic and electric stimulation as a way to enhance speech recognition performance in cochlear implant (CI) users has generated considerable interest in the recent years. The purpose of this study was to evaluate the bimodal advantage of the FS4 speech processing strategy in combination with hearing aids (HA) as a means to improve low-frequency resolution in CI patients. Nineteen postlingual CI adults were selected to participate in this study. All patients wore implants on one side and HA on the contralateral side with residual hearing. Monosyllabic word recognition, speech in noise, and emotion and talker identification were assessed using CI with fine structure processing/FS4 and high-definition continuous interleaved sampling strategies, HA alone, and a combination of CI and HA. The bimodal stimulation showed improvement in speech performance and emotion identification for the question/statement/order tasks, which was statistically significant compared to patients with CI alone, but there were no significant statistical differences in intragender talker discrimination and emotion identification for the happy/angry/neutral tasks. The poorest performance was obtained with HA only, and it was statistically significant compared to the other modalities. The bimodal stimulation showed enhanced speech performance in CI patients, and it improves the limitations provided by electric or acoustic stimulation alone. © 2016 S. Karger AG, Basel.

Gaining competitive advantage in personal dosimetry services through ISO 9001 certification

International Nuclear Information System (INIS)

Noriah, M.A.

2005-01-01

Full text: In Malaysia, the harmonization of dose monitoring for almost 12,000 radiation workers is assigned to the Secondary Standard Dosimetry Laboratory of Malaysian Institute for Nuclear Technology Research, SSDL-MINT. Established in 1980, SSDL-MINT is responsible for improving personal and workplace safety by providing high quality personal dosimetry services. It is important to demonstrate that the performance of personal dosimetry meets recognized standards, to ensure radiation doses to individual workers are within the safe limits and to verify compliance with dose limits. Concern on the quality of personal dosimetry service began to be expressed in 2000. The concern led to the ISO certification, which brought an unprecedented effort characterized by high degree coordination, proper documentation and well trained of personal dosimetry operators. These huge efforts resulted with certification ISO 9002:1994 by the SIRIM International QAS Sdn. Bhd. in January 2002. The adoption of these requirements for the ISO 9002 standard makes routine handling of the process easier, and increases the reliability and effectiveness of the services. This helps to increase the quality and uniformity of personal dosimetry. The revision of the ISO 9002:1994 to ISO 9001:2000 necessitated SSDL-MINT revising its quality management system. The work began in middle 2002, and by May 2003, SSDL-MINT has been upgraded to ISO 9001:2000. Certification to the ISO 9001:2000 demonstrates our ability to consistency provide service that meets the requirements of the customer and the regulatory authority. These includes: improved consistency of service / product performance and therefore higher customer satisfaction levels; uniformity in work processes across organizations; simplified and more uniform structure for quality documents; improved customer perception of the organizations image, culture and performance; reduced number of product and process non-conformances; greater employee

Evaluation of the Cerebral State Index in Cats under Isoflurane Anaesthesia: Dose-Effect Relationship and Prediction of Clinical Signs

Directory of Open Access Journals (Sweden)

Joana R. Sousa

2014-01-01

Full Text Available The performance of the cerebral state index (CSI in reflecting different levels of isoflurane anaesthesia was evaluated in ten cats subjected to four end-tidal isoflurane concentrations (EtIso, each maintained for 15 minutes (0.8%, 1.2%, 1.6%, or 2.0% EtIso. The CSI, hemodynamic data, ocular reflexes, and eye position were recorded for each EtIso concentration. Pharmacodynamic analysis of CSI with EtIso was performed, as well as prediction probability analysis with a clinical scale based on the eye reflexes. The CSI values showed great variability. Between all parameters, burst suppression ratio showed the better fitting with the sigmoidal concentration-effect model (R2=0.93 followed by CSI (R2=0.82 and electromyographic activity (R2=0.79. EtIso was the variable with better prediction of the clinical scale of anaesthesia (prediction probability value of 0.94. Although the CSI values decrease with increasing isoflurane concentrations, the huge variability in CSI values may be a strong limitation for its use in cats and it seems to be no better than EtIso as a predictor of clinical signs.

PYME y cooperativas ante el reto de la RSE: la nueva ISO 26000 (SMEs and cooperatives confront the challenge of CSR: the new ISO 26000

Directory of Open Access Journals (Sweden)

Juan Pablo Landa

2012-05-01

Full Text Available Corporate Social Responsibility is a central issue in modern business and a main factor of companies strategies for competitiveness in a global economy . The recent approval of ISO26000 shows this general tendency to introduce social and environmental principles in global governance and organizational behaviour in all kinds of firms, organizations and multinational corporations. This paper offers a critical approach to the effects of ISO 26000 in the small and medium companies, and cooperatives, too. This norm is not focussed on the particularities of this kind of companies and shows some problems when implementing it in SME & social economy organizations. The question which comes up is if there is a necessity to adapt the implementation of ISO 26000 to these particular firms: in which cases and to what limits. La Responsabilidad Social Corporativa es una cuestión central en la economía moderna, y un factor fundamental en las estrategias competitivas de las empresas, en el marco de una economía globalizada. La reciente aprobación de la norma ISO 26000 recoge la tendencia general de introducir principios sociales y medioambientales en el gobierno global y en la organización de todo tipo de empresas, organizaciones y corporaciones multinacionales. Este artículo ofrece un acercamiento crítico a los efectos de la norma ISO 26000 en las PYMEs y cooperativas. Esta norma no contempla las particularidades de este tipo de compañías, y muestra algunos problemas al implantarlas en PYMEs y organizaciones de la economía social. Se cuestiona la necesidad de adaptar la implementación de la norma ISO 26000 a este tipo de organizaciones, en qué casos, y con qué limites.DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=2049865

Occupational exposures at nuclear power plants. Twelfth annual report of the Isoe programme, 2002

International Nuclear Information System (INIS)

2004-01-01

The Information System on Occupational Exposure (ISOE) was created by the OECD Nuclear Energy Agency in 1992 to promote and co-ordinate international co-operative undertakings in the area of worker protection at nuclear power plants. The ISOE Programme provides experts in occupational radiation protection with a forum for communication and exchange of experience. The ISOE databases enable the analysis of occupational exposure data from the 465 commercial nuclear power plants participating in the Programme (representing some 90 per cent of the world's total operating commercial reactors). The Twelfth Annual Report of the ISOE Programme summarises achievements made during 2002 and compares annual occupational exposure data. Principal developments in ISOE participating countries are also described. (author)

High temperature tensile properties and fracture characteristics of bimodal 12Cr-ODS steel

International Nuclear Information System (INIS)

Chauhan, Ankur; Litvinov, Dimitri; Aktaa, Jarir

2016-01-01

This article describes the tensile properties and fracture characteristics of a 12Cr oxide dispersion strengthened (ODS) ferritic steel with unique elongated bimodal grain size distribution. The tensile tests were carried out at four different temperatures, ranging from room temperature to 700 °C, at a nominal strain rate of 10"−"3 s"−"1. At room temperature the material exhibits a high tensile strength of 1294 MPa and high yield strength of 1200 MPa. At 700 °C, the material still exhibits relatively high tensile strength of 300 MPa. The total elongation-to-failure exceeds 18% over the whole temperature range and has a maximum value of 29% at 600 °C. This superior ductility is attributed to the material's bimodal grain size distribution. In comparison to other commercial, as well as experimental, ODS steels, the material shows an excellent compromise between strength and ductility. The fracture surface studies reveal a change in fracture behavior from a mixed mode fracture at room temperature to fully ductile fracture at 600 °C. At 700 °C, the fracture path changes from intragranular to intergranular fracture, which is associated with a reduced ductility. - Highlights: • The steel has a unique elongated bimodal grain size distribution. • The steel shows an excellent compromise between strength and ductility. • Superior ductility in comparison to other commercial and experimental ODS steels. • Fracture behavior changes from mixed mode fracture at room temperature to fully ductile fracture at 600 °C. • Fracture path changes from intragranular to intergranular fracture at 700 °C.

ISO 50001 for US Commercial Buildings - Current Status and Opportunities

Energy Technology Data Exchange (ETDEWEB)

Liu, Jingjing; Sheaffer, Paul

2017-12-01

''ISO 50001: 2011 Energy management systems – Requirements with guidance for use'' is a voluntary International Standard which provides organizations a proven framework to manage energy and continuously improve their energy performance. Implementing ISO 50001 in the commercial building sector has its unique opportunities and challenges in comparison with the industrial sector. The energy footprint of a portfolio of commercial buildings can be just as significant as a large industrial facility in comparison. There are many energy-saving opportunities in commercial buildings that can be addressed without capital investments, and the perceived risks for making energy improvements can be lower than in the industrial sector. In addition, the energy-consuming systems in commercial buildings are limited in types and have many similarities across buildings, which makes it much easier to standardize many ISO 50001 required processes, 5 procedures and documents to simplify implementation. There are also some sector-unique challenges, such as less familiar with ISO systems and the certification process. Another challenge arises from the complexity in some buildings’ ownership, tenancy, and O&M responsibilities. This whitepaper discusses these opportunities and issues in detail. The paper also recommends the characteristics of organizations in the commercial building sector that can benefit the most from adopting the ISO 50001 standard – namely the “suitable market”. Eight segments (education, food sales, retail, inpatient health care, hospitality, office buildings, laboratories and data centers) within the commercial building sector are highlighted.

The ISO9000 standard in electrical research

Energy Technology Data Exchange (ETDEWEB)

Rodriguez-Ortiz, G.; Davila-Nunez, G.; Gonzalez-Sustaeta, J. [Inst. de Investigaciones Electricas, Cuernavaca (Mexico). Unidad de Sistemas Informaticos

1999-11-01

In this article, the main aspects that are considered important upon applying the ISO9000 standard [ISO 94] in a research institution, company, or group, are described. The 20 sections of the standard are discussed emphasizing the concepts and definitions that can be differently interpreted in the process of elaboration of a quality manual for a group devoted to research, than when they are applied in the elaboration of a manual for a factory that produces material goods. The exposed reasoning was used in the elaboration of the quality manual in the Information Systems Unit of the Electrical Research Institute in Mexico, and it is being used in the installation and operation of the quality system.

Tropical intraseasonal oscillation simulated in an AMIP-type experiment by NICAM

Science.gov (United States)

Kikuchi, Kazuyoshi; Kodama, Chihiro; Nasuno, Tomoe; Nakano, Masuo; Miura, Hiroaki; Satoh, Masaki; Noda, Akira T.; Yamada, Yohei

2017-04-01

It is the first time for the non-hydrostatic icosahedral atmospheric model (NICAM), at a horizontal mesh size of approximately 14-km, to conduct a continuous long-term Atmospheric Model Intercomparison Project-type simulation. This study examines the performance of NICAM in simulating the tropical intraseasonal oscillation (ISO) from a statistical point of view using 30-year data (1979-2008) in the context of the bimodal ISO representation concept proposed by Kikuchi et al., which allows us to examine the seasonally varying behavior of the ISO in great detail, in addition to the MJO working group level 2 diagnostics. It is found that many of the fundamental features of the ISO are well captured by NICAM. The evolution of the ISO convection as well as large-scale circulation over the course of its life cycle is reasonably well reproduced throughout the year. As in the observation, the Madden-Julian oscillation (MJO) mode, characterized by prominent eastward propagation of convection, is predominant during boreal winter, whereas the boreal summer ISO (BSISO) mode, by a combination of pronounced eastward and northward propagation, during summer. The overall shape of the seasonal cycle as measured by the numbers of significant MJO and BSISO days in a month is relatively well captured. Two major biases, however, are also identified. The amplitude of the simulated ISO is weaker by a factor of 2. Significant BSISO events sometimes appear even during winter (December-April), amounting to 30 % of the total significant ISO days as opposed to 2 % in the observation. The results here warrant further studies using the simulation dataset to understand not only many aspects of the dynamics and physics of the ISO but also its role in weather and climate. It is also demonstrated that the concept of the bimodal ISO representation provides a useful framework for assessing model's capability to simulate, and illuminating model's deficiencies in reproducing, the ISO. The nature and

Sustainable development induction in organizations: a convergence analysis of ISO standards management tools' parameters.

Science.gov (United States)

Merlin, Fabrício Kurman; Pereira, Vera Lúciaduarte do Valle; Pacheco, Waldemar

2012-01-01

Organizations are part of an environment in which they are pressured to meet society's demands and acting in a sustainable way. In an attempt to meet such demands, organizations make use of various management tools, among which, ISO standards are used. Although there are evidences of contributions provided by these standards, it is questionable whether its parameters converge for a possible induction for sustainable development in organizations. This work presents a theoretical study, designed on structuralism world view, descriptive and deductive method, which aims to analyze the convergence of management tools' parameters in ISO standards. In order to support the analysis, a generic framework for possible convergence was developed, based on systems approach, linking five ISO standards (ISO 9001, ISO 14001, OHSAS 18001, ISO 31000 and ISO 26000) with sustainable development and positioning them according to organization levels (strategic, tactical and operational). The structure was designed based on Brundtland report concept. The analysis was performed exploring the generic framework for possible convergence based on Nadler and Tushman model. The results found the standards can contribute to a possible sustainable development induction in organizations, as long as they meet certain minimum conditions related to its strategic alignment.

KSC Center Director Bridges accepts an ISO 9001 certification plaque from DNV

Science.gov (United States)

1998-01-01

Center Director Roy Bridges (right) displays the 2000th ISO Certificate Plaque he was given by Dalton Lyon (left) of Det Norske Veritas (DNV), Inc., an international ISO certification organization, at a ceremony at KSC. The plaque is a representation of the ISO 9001 certification awarded to KSC by DNV. ISO 9001 comprises the most detailed, comprehensive set of standard requirements for quality programs established by the International Standards Organization. The presentation followed a successful independent audit by DNV of the KSC Management System in May of this year. The third-party auditors examined about 20 elements of KSC's system, including management responsibility, design control, documentation, test and inspection, and corrective action procedures. DNV found that KSC met or exceeded the stringent quality standards in all areas. KSC will use this certification as a tool to improve an already world- class team. All NASA centers are required by NASA Administrator Daniel S. Goldin to be ISO 9001 registered by September 1999. NASA is the first federal agency to seek the quality certification.

Step of quality assurance preparation on ISO 9001:2000 toward certification

International Nuclear Information System (INIS)

Agustiar

2007-01-01

ISO 9001:2000 is the International Standard for the quality management system that stipulate requirement and recommendation provided for design until product. The standard is also regulated the implementation and evaluation from management system point of view the objective to assure organization will meet specified requirement product. To propose ISO 9001:2000 certification, many steps of action should be carried out. There are 5 primary sections of the quality management system requirements of ISO 9001:2000. Quality Management system, Management responsibility, Resource management, Product realization and Measurement, Analysis and improvement, in which all will be begun with training until evaluation (author)

An analysis of Indonesia’s information security index: a case study in a public university

Science.gov (United States)

Yustanti, W.; Qoiriah, A.; Bisma, R.; Prihanto, A.

2018-01-01

Ministry of Communication and Informatics of the Republic of Indonesia has issued the regulation number 4-2016 about Information Security Management System (ISMS) for all kind organizations. Public university as a government institution must apply this standard to assure its level of information security has complied ISO 27001:2013. This research is a preliminary study to evaluate the readiness of university IT services (case study in a public university) meets the requirement of ISO 27001:2013 using the Indonesia’s Information Security Index (IISI). There are six parameters used to measure the level of information security, these are the ICT role, governance, risk management, framework, asset management and technology. Each parameter consists of serial questions which must be answered and convert to a numeric value. The result shows the level of readiness and maturity to apply ISO 27001 standard.

Predicting the quantifiable impacts of ISO 50001 on climate change mitigation

Energy Technology Data Exchange (ETDEWEB)

McKane, Aimee; Therkelsen, Peter; Scodel, Anna; Rao, Prakash; Aghajanzadeh, Arian; Hirzel, Simon; Zhang, Ruiqin; Prem, Richard; Fossa, Alberto; Lazarevska, Ana M.; Matteini, Marco; Schreck, Bettina; Allard, Fabian; Villegal Alcántar, Noé; Steyn, Karel; Hürdoğan, Ertaç; Björkman, Thomas; O' Sullivan, John

2017-08-01

The ISO 50001-Energy management standard provides a continual improvement framework for organizations to reduce their energy consumption, which in the industrial and commercial (service) sectors, accounts for nearly 40% of global greenhouse gas emissions. Reducing this energy consumption will be critical for countries to achieve their national greenhouse gas reduction commitments. Several national policies already support ISO 50001; however, there is no transparent, consistent process to estimate the potential impacts of its implementation. This paper presents the ISO 50001 Impacts Methodology, an internationally-developed methodology to calculate these impacts at a national, regional, or global scale suitable for use by policymakers. The recently-formed ISO 50001 Global Impacts Research Network provides a forum for policymakers to refine and encourage use of the methodology. Using this methodology, a scenario with 50% of projected global industrial and service sector energy consumption under ISO 50001 management by 2030 would generate cumulative primary energy savings of approximately 105 EJ, cost savings of nearly US $700 billion (discounted to 2016 net present value), and 6500 million metric tons (Mt) of avoided CO₂ emissions. The avoided annual CO₂ emissions in 2030 alone are equivalent to removing 210 million passenger vehicles from the road.

Development of a Prototype Web GIS-Based Disaster Management System for Safe Operation of the Next Generation Bimodal Tram, South Korea—Focused Flooding and Snowfall

Directory of Open Access Journals (Sweden)

Won Seok Jang

2014-04-01

Full Text Available The Korea Railroad Research Institute (KRRI has developed a bimodal tram and advanced bus rapid transit (BRT system which is an optimized public transit system created by mixing the railway’s punctual operation and the bus’ easy and convenient access. The bimodal tram system provides mass-transportation service with an eco-friendly and human-centered approach. Natural disasters have been increasing worldwide in recent years, including floods, snow, and typhoons disasters. Flooding is the most frequent natural disaster in many countries and is increasingly a concern with climate change; it seriously affects people’s lives and productivity, causing considerable economic loss and significant damage. Enhanced conventional disaster management systems are needed to support comprehensive actions to secure safety and convenience. The objective of this study is to develop a prototype version of a Web GIS-based bimodal tram disaster management system (BTDMS using the Storm Water Management Model (SWMM 5.0 to enhance on-time operation and safety of the bimodal tram system. The BTDMS was tested at the bimodal tram test railroad by simulating probable maximum flood (PMF and snow melting for forecasting flooding and snow covered roads. This result could provide the basis for plans to protect against flooding disasters and snow covered roads in operating the bimodal tram system. The BTDMS will be used to assess and predict weather impacts on roadway conditions and operations and thus has the potential to influence economic growth. The methodology presented in this paper makes it possible to manage impacts of flooding and snowfall on urban transportation and enhance operation of the bimodal tram system. Such a methodology based on modeling could be created for most metropolitan areas in Korea and in many other countries.

The Role of ISO 9000 Certification on Waste Management of Leather Industry

International Nuclear Information System (INIS)

Susetyo Hario Putero; Dhani Astuti

2008-01-01

State of industry in an area could increase economy of this area. On the other hand, industry may be produce the waste. There are many factor influencing the success of industrial waste management. At present, ISO 14000 is known as an international environmental management standard. Practically, several matter required for ISO 14000 are similar with ISO 9000. So, the role of ISO 9000 certification on supporting waste management program of leather industry has been studied. Study has been pursued by comparing the environmental management systems of 2 leather industries in Sitimulyo, Piyungan, Bantul. Staff working way has been observed to know the suitability with working procedures and implementation of safety aspect on daily working. Observation of waste treatment facility and measurement of Chrome concentration also has been done. Samples were analysed using AAS method in Department of Chemistry, Faculty of Mathematics and Natural Science, Gadjah Mada University. Decontamination Factor (DF) was calculated by comparing the Chrome concentrations on outside plant and in waste treatment facility. Commitment of management and orderliness of system as required on ISO 9000 certification could push the industry to well execute waste management program as a part of environmental management system. ISO 9000 certification is convinced to make awareness of industry grow for continually improving their capability, including their capacity of waste treatment facility. (author)

Nanotechnology Standardization Activities – Support of U.S. Representation on ISO/TC 229 Nanotechnologies

Energy Technology Data Exchange (ETDEWEB)

Benko, Heather [American National Standards Inst. (ANSI), Washington, DC (United States)

2017-03-14

In carrying out its responsibilities on behalf of the United States, ANSI provides comprehensive, administrative support and expertise on international protocols and procedures to: (1) the U.S. Technical Advisory Group (TAG) to the International Organization for Standardization’s (ISO) Technical Committee (TC) 229 Nanotechnologies, and (2) the corresponding U.S. TAG Working Groups tasked with formulating U.S. positions on topics relevant to nanotechnology standardization. Additionally, secretariat and procedural support is provided for the ISO/TC 229 WG 3 on health, safety and environment, for which the United States was assigned leadership by the participating national body members of ISO/TC 229. As the official entity that serves as the U.S. representative to ISO, ANSI provides not only expert coordination of U.S. positions and representation at ISO but also strategic direction, advice and procedural expertise to facilitate navigation of international issues to promote U.S. positions for incorporation into the ISO/TC 229 program of work necessary to support U.S. objectives.

Blood and urine 8-iso-PGF2α levels in babies of different gestational ages.

Science.gov (United States)

Li, Sitao; Hao, Hu; Zhou, Ping; Gao, Ping Ming; Xiao, Xin

2014-01-01

We measured cord blood and urine 8-iso-prostaglandin F2α (8-iso-PGF2α) levels in babies of different gestational ages to determine lipid peroxidation status. Babies at gestational ages of 28-43 weeks were divided into group A (28-32 weeks), group B (33-36 weeks), group C (37-41 weeks), and group D (42-43 weeks). 8-iso-PGF2α in umbilical cord blood (UCB) at birth and urine at 6 hours after birth was and tested by ELISA. UCB and urine 8-iso-PGF2α levels in group C were 130.09 ± 31.73 pg/ml and 27.14 ± 6.73 pg/ml, respectively. UCB 8-iso-PGF2α levels in group A and B were 188.42 ± 59.34 pg/ml and 189.37 ± 68.46 pg/ml, and urine 8-iso-PGF2α were 32.14 ± 7.32 pg/ml and 30.46 ± 8.83 pg/ml, respectively. Blood and urine 8-iso-PGF2α levels in group D (post-term) were 252.01 ± 46.42 pg/ml and 44.00 ± 8.50 pg/ml. For all babies, UCB and urine iso-PGF2α levels were significantly correlated (r = 0.65, P iso-PGF2α levels in normal full-term babies. Urine 8-iso-PGF2α levels may reflect the extent of lipid peroxidation in babies. In pre-term and post-term babies, there was evidence for increased lipid peroxidation.

Movement, drivers and bimodality of the South Asian High

Directory of Open Access Journals (Sweden)

M. Nützel

2016-11-01

Full Text Available The South Asian High (SAH is an important component of the summer monsoon system in Asia. In this study we investigate the location and drivers of the SAH at 100 hPa during the boreal summers of 1979 to 2014 on interannual, seasonal and synoptic timescales using seven reanalyses and observational data. Our comparison of the different reanalyses focuses especially on the bimodality of the SAH, i.e. the two preferred modes of the SAH centre location: the Iranian Plateau to the west and the Tibetan Plateau to the east. We find that only the National Centers for Environmental Prediction–National Center of Atmospheric Research (NCEP–NCAR reanalysis shows a clear bimodal structure of the SAH centre distribution with respect to daily and pentad (5 day mean data. Furthermore, the distribution of the SAH centre location is highly variable from year to year. As in simple model studies, which connect the SAH to heating in the tropics, we find that the mean seasonal cycle of the SAH and its centre are dominated by the expansion of convection in the South Asian region (70–130° E  ×  15–30° N on the south-eastern border of the SAH. A composite analysis of precipitation and outgoing long-wave radiation data with respect to the location of the SAH centre reveals that a more westward (eastward location of the SAH is related to stronger (weaker convection and rainfall over India and weaker (stronger precipitation over the western Pacific.

Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

Science.gov (United States)

Schwartz-Zimmermann, Heidi E; Hametner, Christian; Nagl, Veronika; Fiby, Iris; Macheiner, Lukas; Winkler, Janine; Dänicke, Sven; Clark, Erica; Pestka, James J; Berthiller, Franz

2017-12-01

The Fusarium mycotoxin deoxynivalenol (DON) is a frequent contaminant of cereal-based food and feed. Mammals metabolize DON by conjugation to glucuronic acid (GlcAc), the extent and regioselectivity of which is species-dependent. So far, only DON-3-glucuronide (DON-3-GlcAc) and DON-15-GlcAc have been unequivocally identified as mammalian DON glucuronides, and DON-7-GlcAc has been proposed as further DON metabolite. In the present work, qualitative HPLC-MS/MS analysis of urine samples of animals treated with DON (rats: 2 mg/kg bw, single bolus, gavage; mice: 1 mg/kg bw, single i.p. injection; pigs: 74 µg/kg bw, single bolus, gavage; cows: 5.2 mg DON/kg dry mass, oral for 13 weeks) revealed additional DON and deepoxy-DON (DOM) glucuronides. To elucidate their structures, DON and DOM were incubated with human (HLM) and rat liver microsomes (RLM). Besides the expected DON/DOM-3- and 15-GlcAc, minor amounts of four DON- and four DOM glucuronides were formed. Isolation and enzymatic hydrolysis of four of these compounds yielded iso-DON and iso-DOM, the identities of which were eventually confirmed by NMR. Incubation of iso-DON and iso-DOM with RLM and HLM yielded two main glucuronides for each parent compound, which were isolated and identified as iso-DON/DOM-3-GlcAc and iso-DON/DOM-8-GlcAc by NMR. Iso-DON-3-GlcAc, most likely misidentified as DON-7-GlcAc in the literature, proved to be a major DON metabolite in rats and a minor metabolite in pigs. In addition, iso-DON-8-GlcAc turned out to be one of the major DON metabolites in mice. DOM-3-GlcAc was the dominant DON metabolite in urine of cows and an important DON metabolite in rat urine. Iso-DOM-3-GlcAc was detected in urine of DON-treated rats and cows. Finally, DON-8,15-hemiketal-8-glucuronide, a previously described by-product of DON-3-GlcAc production by RLM, was identified in urine of DON-exposed mice and rats. The discovery of several novel DON-derived glucuronides in animal urine requires adaptation of

Beneficios de la aplicación de normas internacionales ISO en procesos electorales

Directory of Open Access Journals (Sweden)

Jeffrey Badí Quinteros Basantes

2017-01-01

Full Text Available En este artículo se presentarán los beneficios de la aplicabilidad de las normas internacionales ISO en los procesos electorales, con el fin de poder elevar los niveles de percepción positiva de los ciudadanos. Se verificará la aplicación de normas ISO/TS 17582:2014, Sistemas de Gestión de la Calidad y la norma ISO/IEC 27001:2013, para todas las fases de un proceso electoral. Se expondrán los dominios que forman parte de la norma ISO/TS 17582:2014 , los cuales permiten un proceso de mejoramiento continuo a fin de garantizar la calidad de las metodologías que soportan la organización, administración, gestión, seguimiento y auditorías de un proceso electoral. La norma ISO/IEC 27001:2013 se alinea con la norma ISO9001:2008 para la gestión de seguridad de la información. La aplicación de esta normativa permitirá asegurar la integridad, confidencialidad y disponibilidad de la información durante los procesos electorales.

An iso-erodent map Imo state of Nigeria | Madubuike | International ...

African Journals Online (AJOL)

Among inputs/resources often needed for erosion risk assessment of a region is the iso-erodent map of the region. This is a map showing areas of equal erosion potentials in the region. As Imo and Abia states of Nigeria lie in a high erosion region of the country, it was decided in this work to produce an iso-erodent map of ...

Programación de las normas ISO 12217-1 (2011) e ISO 12217-3 (2011) para el estudio de la estabilidad y flotabilidad de embarcaciones de recreo

OpenAIRE

Gallardo Martínez, Antonio

2013-01-01

Las embarcaciones de recreo para operar dentro de la Comunidad Europea deben de obtener el marcado CE. Para ello se evalúa y clasifica su estabilidad y flotabilidad según la normativa ISO 12217 y se asigna una categoría de diseño (A, B, C o D) adecuada a su diseño y a su carga total máxima. El presente proyecto tiene como objetivo la programación de las normas ISO 12217-1 referente a embarcaciones no propulsadas a vela de eslora igual o superior a 6 m y la norma ISO 12217-3 ...

EPA STANDARDS NETWORK FACT SHEET: ISO 14000: INTERNATIONAL ENVIRONMENTAL MANAGEMENT STANDARDS

Science.gov (United States)

This flyer provides an overview of the ISO 14000 series of International standards, supplying a brief history, structure of the Technical Committee (TC) 207, structure of the U.S. Technical Advisory Group (TAG) to ISO TC-207, status of the Standards development as of June 1997, w...

PENGARUH CSR BERDASAR ISO 26000 TERHADAP NILAI PERUSAHAAN DENGAN KARAKTERSITIK PERUSAHAAN SEBAGAI VARIABEL MODERATING

Directory of Open Access Journals (Sweden)

Sri Wahjuni Latifah

2015-01-01

Full Text Available Research of the influence of ISO 26000 CSR toward the company’s value as a moderating variable which is done on companies listed in Indonesia Stock Exchange. The Company’s characteristics are measured by firm age, size, leverage and profitability. The data analysis was done by using double linear regression models, the first is to see the effect based on the ISO 26000 CSR and firm characteristics on value, and the second is to see the effect of interaction with the ISO 26000 corporate characteristics. The results of the study showed that there was no influence of ISO 26000, the characteristics of the company toward the value of the company. However, moderated ISO 26000 by firm characteristics affect the value of the company.

Providing for transmission in times of scarcity: an ISO cannot do it all

International Nuclear Information System (INIS)

Allen, E.; Ilic, M.; Younes, Z.

1999-01-01

The main purpose of this paper is to point out issues critical for establishing a good transmission strategy in an energy market. First, it is suggested that a transmission strategy must be discussed in the context of a specific market structure. Responsibilities of a transmission system provider differ fundamentally, depending on the type of energy market it is supposed to serve. To show this, a summary of information assumed to be known to an Independent System Operator (ISO) in three energy market structures is given, i.e., (1) a mandatory ISO, (2) an entirely multilateral market and (3) a voluntary ISO. The differences between these three proposals concerning an ISO's responsibility for achieving systemwide efficiency and fair charges for transmission service, particularly at times of scarcity, are analyzed. It is shown that an ISO equipped with the present types of optimization tools for both reliability and efficiency is generally 'blind' to questions of fairness with respect to the individual market participants when providing transmission system support. In order to get around this problem, much more work will have to he done by the technical and regulatory communities. The only tools at an ISO's disposal at present are used for systemwide objectives, such as systemwide reliability. While some of this work is under way, it will take some time to develop the actual ISO tools necessary for implementing the fairness criterion metrics ('standards'), whichever ones the community arrives at. (Developing metrics of fair reliability contributions for the individual market participants is a nonunique process, and it may be very difficult to actually agree upon). Meanwhile, in order to have an ISO actively help energy markets in a fair and efficient way in realistic markets, which are likely to be voluntary ISOs, a system user must become an active part of decision making, indicating how much it wishes to use the system at times of scarcity and at which price. One

ISO-PC Version 1.98: User`s guide

Energy Technology Data Exchange (ETDEWEB)

Rittmann, P.D.

1995-05-02

This document describes how to use Version 1.98 of the shielding program named ISO-PC. Version 1.98 corrects all known errors in ISOSHLD-II. In addition, a few numeric problems have been eliminated. There are three new namelist variables, 25 additional shielding materials, and 5 more energy groups. The two major differences with the original ISOSHLD-II are the removal of RIBD(radioisotope buildup and decay) source generator, and the removal of the non-uniform source distribution parameter, SSV1. This version of ISO-PC works with photon energies from 10 KeV to 10 MeV using 30 energy groups.

Bimodality: A Sign of Critical Behavior in Nuclear Reactions

International Nuclear Information System (INIS)

Le Fevre, A.; Aichelin, J.

2008-01-01

The recently discovered coexistence of multifragmentation and residue production for the same total transverse energy of light charged particles, which has been dubbed bimodality like it has been introduced in the framework of equilibrium thermodynamics, can be well reproduced in numerical simulations of heavy ion reactions. A detailed analysis shows that fluctuations (introduced by elementary nucleon-nucleon collisions) determine which of the exit states is realized. Thus, we can identify bifurcation in heavy ion reactions as a critical phenomenon. Also the scaling of the coexistence region with beam energy is well reproduced in these results from the quantum molecular dynamics simulation program

Implementation of the ISO 14001: 2004 standard at the Florida Bebidas facilities in Coyol of Alajuela

International Nuclear Information System (INIS)

Picado Jimenez, Susana Melissa

2014-01-01

The partial implementation of the ISO 14001: 2004 standard is carried out at the company Florida Bebidas located in Coyol of Alajuela. A bibliographical study is initiated of the documentation that the Company has in others of its facilities on the subject, to comply with the stipulated in the environmental policy of the company. The implementation of the standard is planned by defining the priority environmental aspects according to the objectives, goals and environmental programs to fulfill the new period of the company. The responsibilities of those involved were defined. The documentation is elaborated, including the procedures, instructions for monitoring and measurement, records required by the standard, operational control, preparation and response to environmental emergencies. The verification of the management system is reviewed together with the legal evaluation. Environmental indicators are improved and significant environmental risks are identified to establish the pertinent measures and to reduce the risk index. The importance of implementing ISO 14001: 2004 to the control of procedures is determined, and the records created to follow up on each outstanding environmental aspect. The strict use of each of the established records is recommended to continue the process of standard implementing. (author) [es

Effects of Removing Low-Frequency Electric Information on Speech Perception with Bimodal Hearing

Science.gov (United States)

Fowler, Jennifer R.; Eggleston, Jessica L.; Reavis, Kelly M.; McMillan, Garnett P.; Reiss, Lina A. J.

2016-01-01

Purpose: The objective was to determine whether speech perception could be improved for bimodal listeners (those using a cochlear implant [CI] in one ear and hearing aid in the contralateral ear) by removing low-frequency information provided by the CI, thereby reducing acoustic-electric overlap. Method: Subjects were adult CI subjects with at…

Comparative advantage: the impact of ISO 14001 environmental certification on exports.

Science.gov (United States)

Bellesi, Florencia; Lehrer, David; Tal, Alon

2005-04-01

Relative to the enormous acceptance of the ISO 9000 quality standard, the ISO 14001 environmental management certification has been met with only moderate enthusiasm among industrial facilities. The literature on corporate motivation for ISO 14001 participation is relatively modest considering the enormous number of publications reviewing other aspects of its adoption and implementation. It would seem that the present "marketing" package supporting ISO environmental commitments does not seem to offer sufficiently persuasive incentives for increased sales, either domestically or internationally. While researchers assume that a higher export rate of companies is positively associated with higher ISO participation rates, there have been very few empirical studies that support this inference, and conclusions have not been based on data taken from importing countries orfrom a systematic evaluation of expressed corporate preference for products sold by ISO 14001 certified companies. The present study reports the results of a survey to firms in six countries that are Israel's leading trade partners, importing chemicals, textiles, and produce. The survey results confirm that while the international market still considers price and quality as the paramount factors in selection of suppliers, environmental management systems (EMS) are an important feature that is frequently taken into consideration. EMS certification appears to signify a supplier who is managing the business well and exhibiting ethical responsibility. The European market proved to be more environmentally conscious than those in other industrialized parts of the world. EMS offer a particularly valuable advantage for producers wishing to reach European markets. As policy-makers seek to expand the voluntary adoption of EMS, a clear advantage for exporters should be highlighted among national industries.

IMPLEMENTASI QUALITY MANAGEMENT SYSTEM ISO 9001:2008 DALAM PEMBELAJARAN PRODUKTIF KEAHLIAN TEKNIK MESIN DAN OTOMOTIF SMK

Directory of Open Access Journals (Sweden)

Mochammad Ariful Ulfi

2013-07-01

Full Text Available The implementation of ISO 9001:2008 quality management system in the productive learning on the mechanical engineering and automotive in vocational high school. This research uses qualitative approach in term of a case study. The research is conducted at SMKN I Purwosari. The results of this research show that (1 the reason of the ISO imple­mentation is to obtain community trust, to improve compe­titiveness, and to increase the quality of the graduates; (2 the implementation of the quality management system in the learning process refers to the concept of PDCA of the ISO system; (3 the obstacles occured during the implementation of ISO is due to the lack of teachers’ awareness on the ISO system; and (4 some efforts to overcome those obstacles include developing commitment among all elements, socialization, supervision, and doing some preventive efforts. Penelitian ini menggunakan pendekatan kualitatif dengan rancangan studi kasus. Penelitian dilaksanakan di SMK Negeri 1 Purwosari. Adapun fokus penelitian adalah alasan penerapan ISO, implementasi dalam pembelajaran, hambatan, dan upaya mengatasi hambatan pelaksanaan ISO 9001:2008. Hasil penelitian menunjukkan   (1 alasan penerapan ISO adalah agar sekolah dipercaya masyarakat, meningkatkan daya saing, dan mening­kat­kan mutu lulusan; (2 implementasi dalam pembelajaran mengacu  pada konsep PDCA ke dalam sistem manajemen mutu ISO; (3 hambat­an implementasi ISO adalah tingkat kesadaran guru terhadap ISO yang rendah; (4 upaya mengatasi hambatan adalah membangun komitmen bersama, sosiali­sasi, supervisi, dan melakukan usaha pencegahan.

Organizational leadership: A study on the affects of certification to International Organization for Standardization (ISO)

Science.gov (United States)

Cowart, Jewel S.

Compliance to requirements of ISO is an important leadership problem for the International Aerospace Quality Group (IAQG) and the Aviation, Space and Defense (AS&D) companies. Furthermore, the IAQG seeks to understand the valuation of ISO/AS9100 requirements (2009), audit practices, management functions, business performance, customer satisfaction, and potential future concepts for the standard to assure quality. Since the release of the AS9100C total certification growth surpassed 1,100,000 organizations in 2010 with ISO 9001 series adoption and implementation governing business operations (ASQ, 2012b; ISO, 2011; Bernardo, Llach, & Marimon, 2011). Historians such as Crosby, Juran, Deming, and others established the foundation for quality assurance. Several researchers explored the issues which complicate overall benefits of ISO certification (Iwaro & Mwasha, 2012; Karthi et al., 2012; Sampaio et al., 2009). This study examined the effects on AS&D industries from ISO compliance to identify the implications (of ever-changing requirements) through an online survey of 15,000 practitioners. The research illuminated how ISO affects AS&D industries with current and future requirements for certification. The data showed that 75% of survey respondents report implementation of the AS9100C requirements still has benefits that outweigh the cost. Findings suggest that AS&D industries perceive significant value in the AS9100C document as part of the overall ISO 9000 series. In general, the comments from the survey can provide insight into the affects of ISO certification. The study concludes by recommending continued research to learn of further impacts from ISO certification within AS&D industries to improve the AS9100 document requirements for quality management systems.

Phenol-formaldehyde carbon with ordered/disordered bimodal mesoporous structure as high-performance electrode materials for supercapacitors

Science.gov (United States)

Cai, Tingwei; Zhou, Min; Han, Guangshuai; Guan, Shiyou

2013-11-01

A novel phenol-formaldehyde carbon with ordered/disordered bimodal mesoporous structure is synthesized by the facile evaporation induced self-assembly strategy under a basic aqueous condition with SiO2 particles as template. The prepared bimodal mesoporous carbons (BMCs) are composed of ordered mesoporous and disordered mesoporous with diameter of about 3.5 nm and 7.0 nm, respectively. They can be employed as supercapacitor electrodes in H2SO4 aqueous electrolyte after the simple acid-treatment. BMC exhibits an exceptional specific capacitance of 344 F g-1 at the current density of 0.1 A g-1, although it has a relatively low surface area of 722 m2 g-1. And the BMC electrode displays an excellent cycling stability over 10,000 cycles.

ISO 15189 Accreditation: Navigation Between Quality Management and Patient Safety

Directory of Open Access Journals (Sweden)

Plebani Mario

2017-09-01

Full Text Available Accreditation is a valuable resource for clinical laboratories and the development of an International Standard for their accreditation represented a milestone on the path towards improved quality and safety in laboratory medicine. The recent revision of the International Standard, ISO 15189, has further strengthened its value not only for improving the quality system of a clinical laboratory but also for better answering the request for competence, focus on customers’ needs and ultimate value of laboratory services. Although in some countries more general standards such as ISO 9001 for quality systems or ISO 17025 for testing laboratories are still used, there is increasing recognition of the value of ISO 15189 as the most appropriate and useful standard for the accreditation of medical laboratories. In fact, only this International Standard recognizes the importance of all steps of the total testing process, namely extra-analytical phases, the need to focus on technical competence in addition to quality systems, and the focus on customers’ needs. However, the number of accredited laboratories largely varies between European countries and also major differences affect the approaches to accreditation promoted by the national bodies. In particular, some national accreditation bodies perpetuate the use of fixed scopes, while the European co-operation for accreditation (EA and the European Federation of Laboratory Medicine (EFLM Working Group promote the use of flexible scopes. Major issues in clinical laboratory accreditation are the verification of examination procedures for imprecision, trueness and diagnostic accuracy and for estimating measurement uncertainty. In addition, quality indicators (QIs are a fundamental requirement of the ISO 15189 International Standard.

Incorporating an ISO 8583-Service into an Unreliable Application

OpenAIRE

Funcke, Alexander

2008-01-01

If an existing service is to be made available to a broader audience, via for instance the Internet. The implementation of the service may thereby get many new requirements, such as support for a different access method or stricter authorisation and security policies. This thesis discusses the implementation of an ISO 8583 to XML proxy. ISO 8583 is a widely used financial protocol, and was in this project used to communicate with the backing financial server in order to implement a complete w...

Evaluation of ISO EN 13606 as a result of its implementation in XML.

Science.gov (United States)

Austin, Tony; Sun, Shanghua; Hassan, Taher; Kalra, Dipak

2013-12-01

The five parts of the ISO EN 13606 standard define a means by which health-care records can be exchanged between computer systems. Starting within the European standardisation process, it has now become internationally ratified in ISO. However, ISO standards do not require that a reference implementation be provided, and in order for ISO EN 13606 to deliver the expected benefits, it must be provided not as a document, but as an operational system that is not vendor specific. This article describes the evolution of an Extensible Markup Language (XML) Schema through three iterations, each of which emphasised one particular approach to delivering an executable equivalent to the printed standard. Developing these operational versions and incorporating feedback from users of these demonstrated where implementation compromises were needed and exposed defects in the standard. These are discussed herein. They may require a future technical revision to ISO EN 13606 to resolve the issues identified.

Approaches to the ISO/IEC 17025 accreditation for Pu and U accountancy analysis

International Nuclear Information System (INIS)

Okazaki, Hiro; Sumi, Mika; Abe, Katsuo; Sato, Mitsuhiro; Kageyama, Tomio

2013-01-01

The quality control section of Plutonium Fuel Development Center (PFDC) of Japan Atomic Energy Agency has been analyzing isotopic compositions by Mass Spectrometry as well as content by Isotope Dilution Mass Spectrometry (IDMS) of plutonium and uranium in nuclear materials. Along with establishing and managing the quality assurance system, ensuring the reliability of the analysis data is important. PFDC has been establishing the quality management system with ISO9001. ISO9001 consists of management requirements for quality system of organizations. While ISO/IEC 17025 consists of technical requirements for the competence of testing and calibration laboratories in addition to the management requirements. The quality control section addressed technical improvement to improve further reliability of analysis quality and we have accredited for ISO/IEC 17025 of isotopic compositions and content of plutonium and uranium in nuclear materials in March 2010. In this presentation, we report our approaches to the ISO/IEC 17025 accreditation and operation status. (author)

Evaluation of ISO EN 13606 as a result of its implementation in XML

Science.gov (United States)

Sun, Shanghua; Hassan, Taher; Kalra, Dipak

2013-01-01

The five parts of the ISO EN 13606 standard define a means by which health-care records can be exchanged between computer systems. Starting within the European standardisation process, it has now become internationally ratified in ISO. However, ISO standards do not require that a reference implementation be provided, and in order for ISO EN 13606 to deliver the expected benefits, it must be provided not as a document, but as an operational system that is not vendor specific. This article describes the evolution of an Extensible Markup Language (XML) Schema through three iterations, each of which emphasised one particular approach to delivering an executable equivalent to the printed standard. Developing these operational versions and incorporating feedback from users of these demonstrated where implementation compromises were needed and exposed defects in the standard. These are discussed herein. They may require a future technical revision to ISO EN 13606 to resolve the issues identified. PMID:23995217

Iso-scaling in a microcanonical multifragmentation model

International Nuclear Information System (INIS)

Raduta, R.; Raduta, H.

2003-01-01

A microcanonical multifragmentation model is used to investigate iso-scaling over a broad range of excitation energies, for several values of freeze-out volume and equilibrated sources with masses between 40 and 200 in both primary and asymptotic stages of the decay. It was found that the values of the slope parameters α and β depend on the size and excitation energy of the source and are affected by the secondary decay of primary fragments. It was evidenced that iso-scaling is affected by finite size effects. The evolution of the differences of neutron and proton chemical potentials corresponding to two equilibrated nuclear sources having the same size and different isospin values with temperature and freeze-out volume is presented. (authors)

Incorporating ISO Metadata Using HDF Product Designer

Science.gov (United States)

Jelenak, Aleksandar; Kozimor, John; Habermann, Ted

2016-01-01

The need to store in HDF5 files increasing amounts of metadata of various complexity is greatly overcoming the capabilities of the Earth science metadata conventions currently in use. Data producers until now did not have much choice but to come up with ad hoc solutions to this challenge. Such solutions, in turn, pose a wide range of issues for data managers, distributors, and, ultimately, data users. The HDF Group is experimenting on a novel approach of using ISO 19115 metadata objects as a catch-all container for all the metadata that cannot be fitted into the current Earth science data conventions. This presentation will showcase how the HDF Product Designer software can be utilized to help data producers include various ISO metadata objects in their products.

Integration of distributed plant lifecycle data using ISO 15926 and Web services

International Nuclear Information System (INIS)

Kim, Byung Chul; Teijgeler, Hans; Mun, Duhwan; Han, Soonhung

2011-01-01

Highlights: → The ISO 15926 parts that provide implementation methods are under development. → A prototype of an ISO 15926-based data repository called a facade was implemented. → The prototype facade has the advantages of data interoperability and integration. → These are obtained through the features of ISO 15926 and Web services. - Abstract: Considering the financial, safety, and environmental risks related to industrial installations, it is of paramount importance that all relevant lifecycle information is readily available. Parts of this lifecycle information are stored in a plethora of computer systems, often scattered around the world and in many native formats and languages. These parts can create a complete, holistic set of lifecycle data only when they are integrated together. At present, no software is available that can integrate these parts into one coherent, distributed, and up-to-date set. The ISO 15926 standard has been developed, and in part is still under development, to overcome this problem. In this paper, the authors discuss a prototype of an ISO 15926-based data repository called a facade, and its Web services are implemented for storing the equipment data of a nuclear power plant and servicing the data to interested organizations. This prototype is for a proof-of-concept study regarding the ISO 15926 parts that are currently under development and that are expected to provide implementation methods for the integration of distributed plant systems.

ISOE: an international occupational exposure database and communications network for dose optimisation

International Nuclear Information System (INIS)

Robinson, I.F.; Lazo, E.

1995-01-01

The Information System on Occupational Exposure (ISOE) was launched by the Nuclear Energy Agency (NEA) of the Organisation for Economic Co-operation and Development (OECD) on 1 January 1992 to facilitate the communication of dosimetry and ALARA implementation data among nuclear facilities around the world. Members of ISOE include 51 utilities from 17 countries and regulators from 11 countries, with four regional technical centres administering the system and a Steering Group which manages the work. ISOE includes three databases and a communications network at several levels. The three databases NEA1, NEA2 and NEA3 include varying levels of details, with NEA3 being the most detailed giving task and site specific ALARA practices and experiences. Utility membership of ISOE gives full access to the databases whereas regulators have more limited access. This paper reviews the current status of participation, describes the three databases and the communications network. Some dose data showing trends in particular countries are presented as well as dose data relating to operation cycle length and outage length. The advantages of membership are described, and it is concluded that ISOE holds the potential for both dose and cost savings. (author)

Human fatigue expression recognition through image-based dynamic multi-information and bimodal deep learning

Science.gov (United States)

Zhao, Lei; Wang, Zengcai; Wang, Xiaojin; Qi, Yazhou; Liu, Qing; Zhang, Guoxin

2016-09-01

Human fatigue is an important cause of traffic accidents. To improve the safety of transportation, we propose, in this paper, a framework for fatigue expression recognition using image-based facial dynamic multi-information and a bimodal deep neural network. First, the landmark of face region and the texture of eye region, which complement each other in fatigue expression recognition, are extracted from facial image sequences captured by a single camera. Then, two stacked autoencoder neural networks are trained for landmark and texture, respectively. Finally, the two trained neural networks are combined by learning a joint layer on top of them to construct a bimodal deep neural network. The model can be used to extract a unified representation that fuses landmark and texture modalities together and classify fatigue expressions accurately. The proposed system is tested on a human fatigue dataset obtained from an actual driving environment. The experimental results demonstrate that the proposed method performs stably and robustly, and that the average accuracy achieves 96.2%.

ISO: international standards development for nuclear technology

International Nuclear Information System (INIS)

Becker, K.

1981-01-01

The importance of internationally recognized standards for nuclear technology and safety is rapidly increasing for technical as well as economical and political reasons such as public acceptance and nuclear technology transfer to developing countries. The need for such standards is also evident because of the large number of nuclear installations sited close to international borders, and the export of nuclear installations from relatively few supplier countries to a large number of user countries. It is the purpose of this report to describe briefly the history, organizational structures and procedures, goals, accomplishments, problems, and future needs of the relevant activities of the International Organization for Standardization (ISO). ISO is composed of the partly governmental, partly non-governmental national standards bodies of 86 countries including China. The work of its Technical Committee (TC) 85 'Nuclear Energy' is mostly concerned with industrial applications, contractual aspects and international communication, for the benefit of both developed and developing countries. It works in close liaison with IAEA, which develops Codes and Guides addressed mainly to the regulatory aspects of nuclear power plants in developing countries. ISO/TC 85 has four sub-committees dealing with: (a) Terminology, Definitions, Units and Symbols (Secretariat USA, four working groups (WGs)); (b) Radiation Protection (Secretariat France, ten WGs); (c) Power Reactor Technology (Secretariat Sweden, nine WGs); (d) Nuclear Fuel Technology (Secretariat F.R. Germany, seven WGs). (author)

Contributors to dietary glycaemic index and glycaemic load in the Netherlands: the role of beer

NARCIS (Netherlands)

Sluik, D.; Atkinson, Fiona S.; Brand-Miller, J.; Fogelholm, M.; Raben, A.; Feskens, E.J.M.

2016-01-01

Diets high in glycaemic index (GI) and glycaemic load (GL) have been associated with a higher diabetes risk. Beer explained a large proportion of variation in GI in a Finnish and an American study. However, few beers have been tested according to International Organization for Standardization (ISO)

ISO training program mixes lectures, hands-on exercises

International Nuclear Information System (INIS)

Sakofsky, S.; Vitale, D.

1994-01-01

Early in 1990, the Dresser-Rand Co., made the decision to upgrade its purchased material quality program and pursue ISO 9000 registration for all product divisions. A joint quality-purchasing council from all US based divisions met and developed a new strategy that included: developing and maintaining a common external audit schedule eliminating duplicate audits; development of a formal training program for auditors; implementing a rule for all divisions that called for internal and external audits to be conducted by certified auditors; implementing an aggressive internal audit program for each division preparing for ISO 9001 or 9002 registration. Development of a formal training program began with educating and training future instructors. Two people were selected who had previous audit and quality system experience. Both were sent to various seminars on ISO 9000, attended a lead assessor course, passed the examination, and became registered with the Institute of Quality Assurance (IQA) in the United Kingdom. The original course was developed by a consultant along with one future instructor. Course content used traditional auditing methodology, but included many team exercises including an actual factory audit. The paper describes the methods and contents of this training course

[ISO 9001 conformity in research, teaching and rehabilitation].

Science.gov (United States)

Howorka, K; Kletschka, G; Pumprla, J; Thoma, H

1998-01-01

Quality assurance, in particular in the areas of development and production of medical devices, is one of the tasks of biomedical engineering. The interdisciplinary working group "Functional Rehabilitation and Group Education, Vienna" is committed to the development and implementation of group education models on three levels: (1) direct education/instruction of patients with chronic diseases, (2) university research and teaching, and (3) development of technical aids for rehabilitation and the means for disseminating group education models in rehabilitation and therapy. Major aims were, by generating conformity with ISO 9001 standards, to achieve greater transparency and process optimization with very small resources in university (teaching, research, technical aids) and extra-university (rehabilitation) areas. A secondary aim was the establishment of interdisciplinary (clinical and biomedical) cooperation at university level. In all main areas (research, teaching and group education/instruction), ISO 9001-conformity was achieved by our activities on three methodological levels: (1) description and analysis of processes, (2) use of ISO 9001 standards for evaluating internal processes, and (3) optimization measures. The following article contains relevant elements of the quality manual and quality assurance system, and offers a typical example of innovative cooperation between medicine and medical engineering.

Global Impact Estimation of ISO 50001 Energy Management System for Industrial and Service Sectors

Energy Technology Data Exchange (ETDEWEB)

Aghajanzadeh, Arian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Therkelsen, Peter L. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rao, Prakash [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McKane, Aimee T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2016-08-01

A methodology has been developed to determine the impacts of ISO 50001 Energy Management System (EnMS) at a region or country level. The impacts of ISO 50001 EnMS include energy, CO2 emissions, and cost savings. This internationally recognized and transparent methodology has been embodied in a user friendly Microsoft Excel® based tool called ISO 50001 Impact Estimator Tool (IET 50001). However, the tool inputs are critical in order to get accurate and defensible results. This report is intended to document the data sources used and assumptions made to calculate the global impact of ISO 50001 EnMS.

The neuroprotective effects of α-iso-cubebene on dopaminergic cell death: involvement of CREB/Nrf2 signaling.

Science.gov (United States)

Park, Sun Young; Son, Beung Gu; Park, Young Hoon; Kim, Cheol-Min; Park, Geuntae; Choi, Young-Whan

2014-09-01

As a part of ongoing studies to elucidate pharmacologically active components of Schisandra chinensis, we isolated and studied α-iso-cubebene. The neuroprotective mechanisms of α-iso-cubebene in human neuroblastoma SH-SY5Y cells were investigated. α-Iso-cubebene significantly inhibited cytotoxicity and apoptosis due to 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in dopaminergic SH-SY5Y cells. Pretreatment of cells with α-iso-cubebene reduced intracellular accumulation of ROS and calcium in response to 6-OHDA. The neuroprotective effects of α-iso-cubebene were found to result from protecting the mitochondrial membrane potential. Notably, α-iso-cubebene inhibited the release of apoptosis-inducing factor from the mitochondria into the cytosol and nucleus after 6-OHDA treatment. α-Iso-cubebene also induced the activation of PKA/PKB/CREB/Nrf2 and suppressed 6-OHDA-induced neurotoxicity. α-Iso-cubebene was found to induce phosphorylation of PKA and PKB and activate Nrf2 and CREB signaling pathways in a dose-dependent manner. Additionally, α-iso-cubebene stimulated the expression of the antioxidant response genes NQO1 and HO-1. Finally, α-iso-cubebene-mediated neuroprotective effects were found to be reversible after transfection with CREB and Nrf2 small interfering RNAs.

Interpretation of MS ISO/ IEC 17020

International Nuclear Information System (INIS)

Mohamad Pauzi Ismail

2012-01-01

MS ISO/ IEC 17020 is an international standard which adopted by Malaysian Standard states the requirement criteria for inspection bodies. The author involved in the NDT technical assessment to several NDT companies in Malaysia. The experience in performing NDT assessment activity is explained and discussed. (author)

A Cross-Country Empirical Study Towards the Impact of Following ISO Management System Standards on Euro-Area Economic Confidence

Directory of Open Access Journals (Sweden)

Ştefan Daniel Armeanu

2017-02-01

Full Text Available This study aims to examine the impact of following ISO management system standards on economic sentiment indicator (ESI as proxy of economic agents’ general view concerning economic activity, for 21 European Union member states over 2005-2014. The empirical research comprises ISO standards with reference to management systems towards quality (ISO 9001, ISO 13485, ISO 16949, food safety (ISO 22000, environment (ISO 14001, and information security (ISO 27001. Panel data fixed effects regression models provide support for a positive impact of the quality management systems related to automotive industry, as well as information security management systems, on the ESI. Further, dynamic panel data approach by way of two-step system generalized method of moments emphasizes a positive influence of quality management systems standard for the medical device industry on Euro-area economic confidence, but a negative effect of food safety management systems. Also, ISO 9001, ISO 22000, and ISO 14001 Granger cause ESI.

Research on bimodal particle extinction coefficient during Brownian coagulation and condensation for the entire particle size regime

International Nuclear Information System (INIS)

Tang Hong; Lin Jianzhong

2011-01-01

The extinction coefficient of atmospheric aerosol particles influences the earth’s radiation balance directly or indirectly, and it can be determined by the scattering and absorption characteristics of aerosol particles. The problem of estimating the change of extinction coefficient due to time evolution of bimodal particle size distribution is studied, and two improved methods for calculating the Brownian coagulation coefficient and the condensation growth rate are proposed, respectively. Through the improved method based on Otto kernel, the Brownian coagulation coefficient can be expressed simply in powers of particle volume for the entire particle size regime based on the fitted polynomials of the mean enhancement function. Meanwhile, the improved method based on Fuchs–Sutugin kernel is developed to obtain the condensation growth rate for the entire particle size regime. And then, the change of the overall extinction coefficient of bimodal distributions undergoing Brownian coagulation and condensation can be estimated comprehensively for the entire particle size regime. Simulation experiments indicate that the extinction coefficients obtained with the improved methods coincide fairly well with the true values, which provide a simple, reliable, and general method to estimate the change of extinction coefficient for the entire particle size regime during the bimodal particle dynamic processes.

Plasma 8-iso-Prostaglandin F2α concentrations and outcomes after acute intracerebral hemorrhage.

Science.gov (United States)

Du, Quan; Yu, Wen-Hua; Dong, Xiao-Qiao; Yang, Ding-Bo; Shen, Yong-Feng; Wang, Hao; Jiang, Li; Du, Yuan-Feng; Zhang, Zu-Yong; Zhu, Qiang; Che, Zhi-Hao; Liu, Qun-Jie

2014-11-01

Higher plasma 8-iso-Prostaglandin F2α concentrations have been associated with poor outcome of severe traumatic brain injury. We further investigated the relationships between plasma 8-iso-Prostaglandin F2α concentrations and clinical outcomes in patients with acute intracerebral hemorrhage. Plasma 8-iso-Prostaglandin F2α concentrations of 128 consecutive patients and 128 sex- and gender-matched healthy subjects were measured by enzyme-linked immunosorbent assay. We assessed their relationships with disease severity and clinical outcomes including 1-week mortality, 6-month mortality and unfavorable outcome (modified Rankin Scale score>2). Plasma 8-iso-Prostaglandin F2α concentrations were substantially higher in patients than in healthy controls. Plasma 8-iso-Prostaglandin F2α concentrations were positively associated with National Institutes of Health Stroke Scale (NIHSS) scores and hematoma volume using a multivariate linear regression. It emerged as an independent predictor for clinical outcomes of patients using a forward stepwise logistic regression. ROC curves identified the predictive values of plasma 8-iso-Prostaglandin F2α concentrations, and found its predictive value was similar to NIHSS scores and hematoma volumes. However, it just numerically added the predictive values of NIHSS score and hematoma volume. Increased plasma 8-iso-Prostaglandin F2α concentrations are associated with disease severity and clinical outcome after acute intracerebral hemorrhage. Copyright © 2014 Elsevier B.V. All rights reserved.

A study of ISO Solenoid Valve with static and dynamic characteristics

International Nuclear Information System (INIS)

Jeon, Y. S.; Ju, M. J.; Oh, Y. C.; Kim, D. S.

2009-01-01

The technology of ISO Solenoid Valves is now considered as a core technology in the fields of the production line of semi-conductor chips and the ISO fluid chips for medical applications. And ISO Solenoid Valves, which operate by compressed air, are characterized by high speed response, great repeatability and that the pressure on the cross sectional area of poppet is kept constant regardless of the fluctuation of the pressure exerted on the ports. The primary objective of this study is to compare the optimally designed Solenoid Valve with the actually produced one and to design a power saving circuit which can highly improve the efficiency by providing optimal current according to mechanical load.

ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models.

Science.gov (United States)

Ioannou, Kyriaki; Cheng, Kai Fan; Crichlow, Gregg V; Birmpilis, Anastasios I; Lolis, Elias J; Tsitsilonis, Ourania E; Al-Abed, Yousef

2014-10-01

Macrophage migration inhibitory factor (MIF) is a pleiotropic pro-inflammatory cytokine, which possesses a contributing role in cancer progression and metastasis and, thus, is now considered a promising anticancer drug target. Many MIF-inactivating strategies have proven successful in delaying cancer growth. Here, we report on the synthesis of ISO-66, a novel, highly stable, small-molecule MIF inhibitor, an analog of ISO-1 with improved characteristics. The MIF:ISO-66 co-crystal structure demonstrated that ISO-66 ligates the tautomerase active site of MIF, which has previously been shown to play an important role in its biological functions. In vitro, ISO-66 enhanced specific and non-specific anticancer immune responses, whereas prolonged administration of ISO-66 in mice with established syngeneic melanoma or colon cancer was non-toxic and resulted in a significant decrease in tumor burden. Subsequent ex vivo analysis of mouse splenocytes revealed that the observed decrease in tumor growth rates was likely mediated by the selective in vivo expansion of antitumor-reactive effector cells induced by ISO-66. Compared to other MIF-inactivating strategies employed in vivo, the anticancer activity of ISO-66 is demonstrated to be of equal or better efficacy. Our findings suggest that targeting MIF, via highly specific and stable compounds, such as ISO-66, may be effective for cancer treatment and stimulation of anticancer immune responses.

ISO 9000 and 10CFR50, appendix B-one, both, or neither?

International Nuclear Information System (INIS)

Nau, D.C.; Hunt, G.L.

1993-01-01

The evolution of quality system requirements has led to the development of standards that either have been tailored for use in specific industries (as in the case of 10CFR50, Appendix B) or have been made generic for use in commercial operations (as in the case of the ISO 9000 series of standards). The elements of many quality systems are shared to a large degree, and the requirements of the standards only generally differ in certification, training, and documentation requirements. The proof of conformance to the requirements of 10CFR50, Appendix B, and ISO 9001 is in large part identical. Table I provides an example of the quality elements common between 10CFR50, Appendix B, and ISO 9001. Substantive proof that a supplier's qualification system meets the requirements of 10CFR50, Appendix B, can substantially be used as proof of conformance to ISO 9001

Bi-modal stimulation in the treatment of tinnitus: a study protocol for an exploratory trial to optimise stimulation parameters and patient subtyping.

Science.gov (United States)

D'Arcy, Shona; Hamilton, Caroline; Hughes, Stephen; Hall, Deborah A; Vanneste, Sven; Langguth, Berthold; Conlon, Brendan

2017-10-25

Tinnitus is the perception of sound in the absence of a corresponding external acoustic stimulus. Bimodal neuromodulation is emerging as a promising treatment for this condition. The main objectives of this study are to investigate the relevance of interstimulus timing and the choices of acoustic and tongue stimuli for a proprietary bimodal (auditory and somatosensory) neuromodulation device, as well as to explore whether specific subtypes of patients are differentially responsive to this novel intervention for reducing the symptoms of chronic tinnitus. This is a two-site, randomised, triple-blind, exploratory study of a proprietary neuromodulation device with a pre-post and 12-month follow-up design. Three different bimodal stimulation parameter sets will be examined. The study will enrol 342 patients, split 80:20 between two sites (Dublin, Ireland and Regensburg, Germany), to complete 12 weeks of treatment with the device. Patients will be allocated to one of three arms using a stepwise stratification according to four binary categories: tinnitus tonality, sound level tolerance (using loudness discomfort level of Tinnitus Handicap Inventory and the Tinnitus Functional Index, after 12 weeks of intervention. Clinical efficacy will be further explored in a series of patient subtypes, split by the stratification variables and by presence of a somatic tinnitus. Evidence for sustained effects on the psychological and functional impact of tinnitus will be followed up for 12 months. Safety data will be collected and reported. A number of feasibility measures to inform future trial design include: reasons for exclusion, completeness of data collection, attrition rates, patient's adherence to the device usage as per manufacturer's instructions and evaluation of alternative methods for estimating tinnitus impact and tinnitus loudness. This study protocol is approved by the Tallaght Hospital/St. James's Hospital Joint Research Ethics Committee in Dublin, Ireland, and by the

ISO 9001 laatujärjestelmän liittäminen osaksi ISM manuaalia

OpenAIRE

Koskinen, Ville

2016-01-01

Lopputyön aiheena on Turkulaisen varustamon VG-Shipping Oy toimeksiantona selvittää ISO 9001 standardin vaatimusten mukaisten ohjeistuksien liittäminen yrityksen voimassa olevaan turvallisuusjohtamisjärjestelmään (ISM) ja yhdistetyn manuaalin rakentaminen vastaamaan molempien standardien (ISM koodi ja ISO 9001 standardi) vaatimuksia, siten että varustamon alukset eivät ole ISO 9001 luokiteltuja vaan ainoastaan ISM koodin mukaan auditoituja. Lopullisena toimenpiteenä on hyväksyttää ja audit...

[Effects of the ISO 15189 accreditation on Nagoya University Hospital].

Science.gov (United States)

Yoshiko, Kenichi

2012-07-01

The Department of Clinical Laboratory, Nagoya University Hospital acquired ISO 15189 accreditation in November, 2009. The operation of our Quality Management System (QMS) was first surveyed in October, 2010. In this paper, we reported the activity for the preparation and operation of our QMS and the effects of ISO 15189 accreditation. We investigated the changes in the number and content on nonconformities, incident reports and complaints before and after accreditation as indicators to evaluate the effect of ISO 15189 accreditation. Post accreditation, the number of nonconformities and incident reports decreased, seeming to show an improvement of quality of the laboratory activity; however, the number of complaints increased. We identified the increase of complaints at the phlebotomy station. There had been some problems with blood sampling in the past, but it seemed that staff had a high level of concern regarding these problems at the phlebotomy station and took appropriate measures to resolve the complaints. We confirmed that the ISO 15189 accreditation was instrumental in the improvements of the safety and efficiency on laboratory works. However there was a problem that increase of overtime works to operate the QMS. We deal with development of a laboratory management system using IT recourses to solve the problem.

The role of the IEC and ISO in radiological protection

International Nuclear Information System (INIS)

White, D.F.

1976-01-01

The history, objectives, structures and functions of the International Electrotechnical Commission (IEC) and the International Organisation for Standardisation (ISO) are summarized. The IEC is affiliated to the ISO as its electrical division, but has technical and financial autonomy. Member countries of the EEC may be committed to the adoption of their formal agreements ('Standards') if these become incorporated as Directives. The national standardisation organisations, such as BSI in the U.K., form national committees and are responsible for submitting to the IEC the co-ordinated national viewpoints on particular subjects. The overall links between the technical committees and sub-committees of the ISO, IEC and BSI in the field of radiological protection are tabulated, and the relevant International Standards produced, or in the course of preparation, by the appropriate committees of the ISO and the IEC are listed. The bulk of the effort of the BSI committees is now aimed at the production of acceptable international standards. Compatible national standards then follow. This policy is in contrast to the earlier initial emphasis on national standards, and the improved international collaboration has had two welcome effects. The selection of proposals for standards is more critical, and compatibility with the relevant ICRP and ICRU publications is almost a prerequisite for any international standard. (U.K.)

Improvement of and Parameter Identification for the Bimodal Time-Varying Modified Kanai-Tajimi Power Spectral Model

Directory of Open Access Journals (Sweden)

Huiguo Chen

2017-01-01

Full Text Available Based on the Kanai-Tajimi power spectrum filtering method proposed by Du Xiuli et al., a genetic algorithm and a quadratic optimization identification technique are employed to improve the bimodal time-varying modified Kanai-Tajimi power spectral model and the parameter identification method proposed by Vlachos et al. Additionally, a method for modeling time-varying power spectrum parameters for ground motion is proposed. The 8244 Orion and Chi-Chi earthquake accelerograms are selected as examples for time-varying power spectral model parameter identification and ground motion simulations to verify the feasibility and effectiveness of the improved bimodal time-varying modified Kanai-Tajimi power spectral model. The results of this study provide important references for designing ground motion inputs for seismic analyses of major engineering structures.

A Novel Method of Extraction of Blend Component Structure from SANS Measurements of Homopolymer Bimodal Blends.

Science.gov (United States)

Smerdova, Olga; Graham, Richard S; Gasser, Urs; Hutchings, Lian R; De Focatiis, Davide S A

2014-05-01

A new method is presented for the extraction of single-chain form factors and interchain interference functions from a range of small-angle neutron scattering (SANS) experiments on bimodal homopolymer blends. The method requires a minimum of three blends, made up of hydrogenated and deuterated components with matched degree of polymerization at two different chain lengths, but with carefully varying deuteration levels. The method is validated through an experimental study on polystyrene homopolymer bimodal blends with [Formula: see text]. By fitting Debye functions to the structure factors, it is shown that there is good agreement between the molar mass of the components obtained from SANS and from chromatography. The extraction method also enables, for the first time, interchain scattering functions to be produced for scattering between chains of different lengths. [Formula: see text].

Small Low Mass Advanced PBR's for Bi-Modal Operation

Science.gov (United States)

Ludewig, Hans; Todosow, Michael; Powell, James R.

1994-07-01

A preliminary assessment is made of a low mass bi-modal reactor for use as a propulsion unit and as a heat source for generating electricity. This reactor is based on the particle bed reactor (PBR) concept. It will be able to generate both thrust and electricity simultaneously. This assessment indicates that the reactor can generate approximately 6.8 (4) N of thrust using hydrogen as a coolant, and 100 KWe using a closed Brayton cycle (CBC) power conversion system. Two cooling paths pass through the reactor allowing simultaneous operation of both modes. The development of all the components for this reactor are within the experience base of the NTP project.

DIFFERENCES IN MANAGER ASSESSMENTS OF ISO 14000 STANDARD IMPLEMENTATION IN TURKEY

Directory of Open Access Journals (Sweden)

Sıtkı Gözlü

2005-12-01

Full Text Available This study reports the results of a survey about the improvements achieved as result of ISO 14000 Environmental Management System (EMS standard implementation and the differences of improvements with respect to firm characteristics. A survey has been conducted in order to explain the improvements related to environmental management process and overall firm performance. The survey involved sixty-six enterprises implementing ISO 14000 EMS standard in Turkey. In order to assess improvements obtained from ISO 14000 EMS implementation, statements related to environmental management process and overall firm performance indicators have been prepared. The statements in this study are relevant to previous research. A factor analysis was employed to determine the factors of the variables explaining improvements. Nine factors have been identified related to achieved improvements, such as establishment of pro-active environmental management system, effectiveness in resource utilization, effectiveness of process control, relationships with industry and government, meeting expectations of stakeholders, demonstration of social responsibility, profitability, productivity, and competitiveness. Then, a T- test was conducted to determine the differences of managers’ assessments with respect to certain firm characteristics. The findings have shown that there are differences in the assessments of improvements achieved as a result of ISO 14000 EMS standard implementation with respect to sales volume, foreign-capital possession, and ISO 14000 EMS standard implementation. On the other hand, industrial sector, age of establishment, and export orientation are not statistically significant for the differences in the assessments of improvements.

Laboratory accreditation complying with ISO 25 Guide (IRAM 301): Industrial radiography method

International Nuclear Information System (INIS)

Schneebeli, Jorge E.; Zampini, Juan J.; Naucevich, Alfredo

2000-01-01

The ISO 25 Guide (IRAM 301) replaced by ISO 17025 is the standard applied for the implementation of a quality system in a test or calibration laboratory. This document is not known as ISO 9000, but it is the proper standard for this kind of laboratory. This document establishes requirements no just for the quality system in general, but on technical competence, that means the laboratory technical aptitude to carry out the tests. The aim of this paper is to comment the criteria used in the Radiographic Laboratory of CEMEC, that have been assessed by the United King dome Accreditation Service (UKAS). (author)

Human mammary epithelial cells exhibit a bimodal correlated random walk pattern.

Science.gov (United States)

Potdar, Alka A; Jeon, Junhwan; Weaver, Alissa M; Quaranta, Vito; Cummings, Peter T

2010-03-10

Organisms, at scales ranging from unicellular to mammals, have been known to exhibit foraging behavior described by random walks whose segments confirm to Lévy or exponential distributions. For the first time, we present evidence that single cells (mammary epithelial cells) that exist in multi-cellular organisms (humans) follow a bimodal correlated random walk (BCRW). Cellular tracks of MCF-10A pBabe, neuN and neuT random migration on 2-D plastic substrates, analyzed using bimodal analysis, were found to reveal the BCRW pattern. We find two types of exponentially distributed correlated flights (corresponding to what we refer to as the directional and re-orientation phases) each having its own correlation between move step-lengths within flights. The exponential distribution of flight lengths was confirmed using different analysis methods (logarithmic binning with normalization, survival frequency plots and maximum likelihood estimation). Because of the presence of non-uniform turn angle distribution of move step-lengths within a flight and two different types of flights, we propose that the epithelial random walk is a BCRW comprising of two alternating modes with varying degree of correlations, rather than a simple persistent random walk. A BCRW model rather than a simple persistent random walk correctly matches the super-diffusivity in the cell migration paths as indicated by simulations based on the BCRW model.

Human mammary epithelial cells exhibit a bimodal correlated random walk pattern.

Directory of Open Access Journals (Sweden)

Alka A Potdar

2010-03-01

Full Text Available Organisms, at scales ranging from unicellular to mammals, have been known to exhibit foraging behavior described by random walks whose segments confirm to Lévy or exponential distributions. For the first time, we present evidence that single cells (mammary epithelial cells that exist in multi-cellular organisms (humans follow a bimodal correlated random walk (BCRW.Cellular tracks of MCF-10A pBabe, neuN and neuT random migration on 2-D plastic substrates, analyzed using bimodal analysis, were found to reveal the BCRW pattern. We find two types of exponentially distributed correlated flights (corresponding to what we refer to as the directional and re-orientation phases each having its own correlation between move step-lengths within flights. The exponential distribution of flight lengths was confirmed using different analysis methods (logarithmic binning with normalization, survival frequency plots and maximum likelihood estimation.Because of the presence of non-uniform turn angle distribution of move step-lengths within a flight and two different types of flights, we propose that the epithelial random walk is a BCRW comprising of two alternating modes with varying degree of correlations, rather than a simple persistent random walk. A BCRW model rather than a simple persistent random walk correctly matches the super-diffusivity in the cell migration paths as indicated by simulations based on the BCRW model.

Occupational exposures at nuclear power plants. Fourteenth annual report of the ISOE programme, 2004

International Nuclear Information System (INIS)

2006-01-01

The ISOE Programme was created by the OECD Nuclear Energy Agency in 1992 to promote and co-ordinate international co-operative undertakings in the area of worker protection at nuclear power plants. The programme provides experts in occupational radiation protection with a forum for communication and exchange of experience. The ISOE databases enable the analysis of occupational exposure data from 478 operating and shutdown commercial nuclear power plants participating in the programme (representing some 90% of the world's total operating commercial reactors). The Fourteenth Annual Report of the ISOE Programme summarises achievements made during 2004 and compares annual occupational exposure data. Principal developments in ISOE participating countries are also described. (author)

Occupational exposures at nuclear power plants. Eleventh annual report of the Isoe programme, 2001

International Nuclear Information System (INIS)

2002-01-01

The ISOE Programme was created by the OECD Nuclear Energy Agency in 1992 to promote and co-ordinate international co-operative undertakings in the area of worker protection at nuclear power plants. The programme provides experts in occupational radiation protection with a forum for communication and exchange of experience. The ISOE databases enable the analysis of occupational exposure data from the 452 commercial nuclear power plants participating in the programme (representing some 90 per cent of the world's total operating commercial reactors). The Eleventh Annual Report of the ISOE Programme summarises achievements made during 2001 and compares annual occupational exposure data. Principal developments in ISOE participating countries are also described. (author)

Estimating ecosystem iso/anisohydry using microwave satellite data and its applications in ecohydrology

Science.gov (United States)

Li, Y.; Guan, K.; Gentine, P.; Konings, A. G.; Bhattacharya, A.; Meinzer, F. C.; Kimball, J. S.; Xu, X.; Anderegg, W.; McDowell, N. G.; Martínez-Vilalta, J.; Long, D. G.; Good, S. P.

2017-12-01

The concept of iso/anisohydry describes the degree to which plants regulate their water status, operating from isohydric with strict stomatal closure to anisohydric with greater stomatal conductance under drying conditions. Though some species-level measures of iso/anisohydry exist at limited locations, ecosystem scale information is still largely unavailable. In this study, we use diurnal observations from active (Ku-Band backscatter from QuikSCAT) and passive (X-band Vegetation Optical Depth [VOD] from AMSR-E) microwave satellite data to estimate global ecosystem iso/anisohydry. The two independent estimates from radar backscatter and VOD show good agreement at low and mid-latitudes but diverge at high latitudes. Grasslands, croplands, wetlands, and open shrublands are more anisohydric, whereas evergreen broadleaf and deciduous broadleaf forests are more isohydric. The direct validation with upscaled in-situ species iso/anisohydry estimates indicates that the VOD estimates have much better agreement than the backscatter in terms of their iso/anisohydry metrics. The indirect validation suggests that both estimates are consistent with prior knowledge that vegetation water status of anisohydric ecosystems more closely tracks environmental fluctuations of water availability and demand than their isohydric counterparts. The ecosystem level iso/anisohydry can be applied to reveal new insights into spatio-temporal ecosystem response to droughts. We conducted a case study to demonstrate the potential application of iso/anisohydry. We find that during the 2011 drought in US, over the drought affected region in the southern US, isohydric ecosystems experienced larger decline in productivity (NDVI and GPP) than anisohydric ones. However, during the 2012 drought in central US, both isohydric and anisohydric ecosystems exhibited similar decline in productivity.

Listen to ISO 9001:2015 for organizational competitiveness: Correlation between change management and improvement

OpenAIRE

Fonseca Luis Miguel; Domingues José Pedro

2017-01-01

In their quest to achieve superior performance and business results, organizations have extensively adopted models such as ISO 9001 Quality Managements Standards. Research supports that Quality Management System brings significant benefits for organizations competitiveness and success and more than 1 million organizations of all activity sectors worldwide have implemented ISO 9001. In a world of increasingly complexity and interconnection, the revised ISO 9001:2015 International Standard aims...

TANGGUNG JAWAB SOSIAL BERDASARKAN ISO 26000 DAN NILAI PERUSAHAAN YANG LISTED DI BURSA EFEK INDONESIA

Directory of Open Access Journals (Sweden)

Sri Wahjuni Latifah

2012-01-01

Full Text Available The research topic concern with corporate responsibility towards the environment related to the firm value. The objective of this research is to test compliance level of the public company in Indonesia against ISO 26000. The samples in this research are 36 companies which include LQ 45 that was chosen by using purposive sampling method. Techniques of data analysis were conducted by using the index that was analyzed with descriptive statistical techniques. The results of this study found that compliance levels are high (0.68. Similarly, seen from the value of the firm as measured by Tobin’q that the company has conducted environmental responsibility is also high (2.12.

Corporate environmental policy statements in mainland China: to what extent do they conform to ISO 14000 documentation?

Science.gov (United States)

Chung, Shan Shan; Fryxell, Gerald E; Lo, Carlos W H

2005-04-01

For decades, industry has been the main source of pollution in China. Determined to make changes, the mainland Chinese authorities have decided to promote mechanisms that incorporate environmental concerns into the internal management of enterprises. This is manifested in the rapid adoption of the ISO14000 standards, including a significant increase in ISO14001 registrations in China. Thus, this study examined the environmental policy statements of 106 certified facilities in mainland China against a strict interpretation of the mandatory requirements of the ISO 14001:1996 standard and the nonmandatory ISO14004 requirements in order to shed some light on the implementation of environmental management systems in an emerging economic giant. It was decided to analyze the environmental policy statement because such a statement is a core element in the ISO system of environmental management of each facility and there are relatively clear and specific requirements on what an environmental policy statement shall include. An analysis of the contents of the environmental policy statements shows that conformance to the relevant requirements of both the mandatory ISO14001 standard and the nonmandatory ISO14004 standard is far from impressive and that the facilities in our sample seldom went beyond the minimum requirements. By using ISO14001 and ISO14004 conformance scores as the dependent variables, we found that conformity to ISO14001 and overall conformance to ISO14000 series can be explained to some extent by the degree of top management commitment, the experience with informal environmental management systems, and the form of ownership of the facilities.

Listen to ISO 9001:2015 for organizational competitiveness: Correlation between change management and improvement

Directory of Open Access Journals (Sweden)

Fonseca Luis Miguel

2017-07-01

Full Text Available In their quest to achieve superior performance and business results, organizations have extensively adopted models such as ISO 9001 Quality Managements Standards. Research supports that Quality Management System brings significant benefits for organizations competitiveness and success and more than 1 million organizations of all activity sectors worldwide have implemented ISO 9001. In a world of increasingly complexity and interconnection, the revised ISO 9001:2015 International Standard aims to ensure that Quality Management Systems are flexible while remaining reliable. The concept of Change Management was introduced in the standard and Improvement can be achieved both in a continual/incremental mode (already present in the ISO 9001:2008 edition and in a breakthrough change/disruptive mode (new in ISO 9001:2015. ISO 9001:2015 is now closer to Business Excellence Models, such as the EFQM, that highlight the need for agility and flexibility for enduring success. To access if organizations that have already implemented ISO 9001:2015 are indeed managing change and achieving improvement, and if there is a relationship between these two variables, a survey was held with IRCA ISO 9001 Registered Auditors on a worldwide basis. Sample normality was confirmed trough Kolmogorov-Smirnov Test and the hypothesis was tested by using Pearson Correlation coefficient. The findings show that the auditee organizations have positively implemented ISO 9001:2015 requirements on change management and improvement. There is also a strong positive correlation between change management and improvement, suggesting that the organizations that properly manage change by planning, designing, implementing, and controlling change in an effective and efficient way, demonstrate a higher level of performance and results improvement. These conclusions have significant implications for the Quality/Organizational Excellence Management Body of Knowledge, requiring a new way of

Vergelijking van een tijd besparende analysemethode voor hydroxyproline met ISO 3496-1978

NARCIS (Netherlands)

Cazemier, G.; Tuinstra, L.G.M.Th.; Werdmuller, G.A.

1988-01-01

De bepaling van hydroxyproline volgens de referentiemethode ISO 3496 is zeer tijdrovend. In een door het Nordisk Metodikkomitti för Livsmedel voorgestelde methode is een aantal wijzigingen ten opzichte van ISO 3496 aangebracht die de analysetijd per monster sterk verkorten. Om na te gaan of deze

Analysis of the Air Force ISO 14001 Pilot Study Conducted by DoD

National Research Council Canada - National Science Library

Harris, Rodney

2000-01-01

The Department of Defense (DoD) conducted an ISO 14001 pilot study with the primary goal of determining how ISO 14001 could help DoD organizations reduce risks, improve compliance with environmental regulations, enhance stewardship...

Urine temperature as an index for the core temperature of industrial workers in hot or cold environments

Science.gov (United States)

Kawanami, Shoko; Horie, Seichi; Inoue, Jinro; Yamashita, Makiko

2012-11-01

Workers working in hot or cold environments are at risk for heat stroke and hypothermia. In Japan, 1718 people including 47 workers died of heat stroke in 2010 (Ministry of Health Labour and Welfare, Japan 2011). While the American Conference of Governmental Industrial Hygienists (ACGIH) recommendation lists the abnormal core temperature of workers as a criterion for halting work, no method has been established for reliably measuring core temperatures at workplaces. ISO 9886 (Ergonomics-evaluation of thermal strain by physiological measurements. ISO copyright office, Geneva, pp 3-14; 2004) recognizes urine temperature as an index of core temperature only at normal temperature. In this study we ascertained whether or not urine temperature could serve as an index for core temperature at temperatures above and below the ISO range. We measured urine temperature of 31 subjects (29.8 ± 11.9 years) using a thermocouple sensor placed in the toilet bowl at ambient temperature settings of 40, 20, and 5˚C, and compared them with rectal temperature. At all ambient temperature settings, urine temperature correlated closely with rectal temperature exhibiting small mean bias. Urine temperature changed in a synchronized manner with rectal temperature at 40˚C. A Bland and Altman analysis showed that the limits of agreement (mean bias ± 2SD) between rectal and urine temperatures were -0.39 to +0.15˚C at 40˚C (95%CI -0.44 to +0.20˚C) and -0.79 to +0.29˚C at 5˚C (-0.89 to +0.39˚C). Hence, urine temperature as measured by the present method is a practical surrogate index for rectal temperature and represents a highly reliable biological monitoring index for assessing hot and cold stresses of workers at actual workplaces.

ISO 9001 benefits and pitfalls: the path to successful certification.

Science.gov (United States)

Krause, M S

1996-09-01

The lifeblood of a business is developing and commercializing new products with minimum cost and time and maximum quality. Implementation of a quality management system is often used to achieve these goals, and the ISO 9001 standard for a business quality system is rapidly becoming the model of choice. The existence of an ISO-compliant system is a key to meeting the forthcoming regulatory requirements in the European Union and the US Food and Drug Administrations's proposed good management practices. DuPont has demonstrated leadership in the achievement of ISO registration. I describe the path to these successful registrations along with key lessons from the experience. Elements of success are management commitment, adequate resources, education, communication, total organizational involvement, and auditing of system performance. For the system to flourish and provide benefits to the users, sufficient time must be allocated for the organization to change.

Formation of iso-ursodeoxycholic acid during administration of ursodeoxycholic acid in man

NARCIS (Netherlands)

Beuers, U.; Fischer, S.; Spengler, U.; Paumgartner, G.

1991-01-01

The appearance of iso-ursodeoxycholic acid (isoUDCA; 3 beta,7 beta-dihydroxy-5 beta-cholan-24-oic acid) in serum of patients with chronic cholestatic liver disease and of healthy subjects during administration of ursodeoxycholic acid (UDCA) is reported. Comparison of the mass spectrum of the newly

Handbook on Life Cycle Assessment. Operational Guide to the ISO Standards

Energy Technology Data Exchange (ETDEWEB)

Guinee, J.B. [Centre of Environmental Studies, Leiden University, Leiden (Netherlands)

2002-04-01

In 1992 the Centre of Environmental Science (CML) at Leiden University, The Netherlands, published a Guide on Environmental Life Cycle Assessment (LCA) methodology, setting the standard for a long time. Since then LCA methodology has progressed enormously and the International Organization for Standardization (ISO) has published a series of Standards on LCA. These developments have now been incorporated into a new Handbook on LCA authored by CML in cooperation with a number of other important institutes in the area of LCA. The general aim of this Handbook on LCA is to provide a stepwise 'cookbook' with operational guidelines for conducting an LCA study step-by-step, justified by a scientific background document, based on the ISO Standards for LCA. The different ISO elements and requirements are made operational to the 'best available practice' for each step. CML is strongly involved in the development of a standard methodology to determine environmental impacts of products, i.e., LCA. This is done within international fora such as the Society for Environmental Toxicology and Chemistry (SETAC), the International Organization for Standardization (ISO), and the United Nations Environmental Programme (UNEP)

PENGUKURAN KUALITAS PERANGKAT LUNAK SISTEM INFORMASI HOTEL BERBASIS STANDARD ISO 9126

Directory of Open Access Journals (Sweden)

Asih Sutanti

2016-02-01

Full Text Available Penelitian ini bertujuan bagaimana mengukur perangkat lunak yang dilihat dari sudut pandang produk, mengukur kualitas perangkat  lunak Sistem Informasi Hotel yang memerlukan  alat bantu untuk mempermudah melakukan pengukuran kualitas software tersebut berdasarkan ISO 9126 yang sesuai dengan enam karakteristik dari model kualitas software/perangkat lunak yaitu Functionability, Reliability, usability, efesiency, maintainability dan portability. Faktor kualitas umum yang paling penting diurutkan dan ditambahkan ke sub-faktor dari ISO 9126. Sehingga pihak manajemen dalam pengukurannya lebih akurat dalam memperoleh informasi untuk menentukan keputusan strategis. Melalui pemrosesan data dari masukan pengguna terhadap tingkat preferensi faktor dan sub-faktor kualitas akan diperoleh bobot faktor kualitas dan bobot relatif sub-faktor kualitas. Perkalian kedua nilai tersebut akan menghasilkan bobot absolut yang kemudian dikalikan dengan penilaian kriteria aplikasi hotel dari pengguna. Hasil akhirnya berupa nilai kualitas total dari aplikasi perangkat lunak Sistem Informasi Hotel. Setelah dilakukan pengukuran dengan enam karakteristik Standart ISO 9126, diperoleh nilai  Sistem Informasi Hotel 13.25 yang merupakan hasil pengukuran kualitas sehingga aplikasi ini tidak masuk kategori standar ISO 9126 karena ada Karakteristik Portability yait u unsur Adaptability, dan Installability tidak terpenuhi.

Environmental Management Systems (EMS ISO 14001 Implementation in Construction Industry: A Malaysian Case Study

Directory of Open Access Journals (Sweden)

Sumiani Yusoff

2015-03-01

Full Text Available This study seeks to explore the crucial part in EMS implementation; i.e. environmental aspects and impacts, Good Environmental Practice to be developed in construction site, as well as the level of awareness or understanding amongst site staffs on ISO 14001 EMS implementation in their organizations. Data were collected via interviews, surveys and site visits. A number of environmental aspects and impacts, and Good Environmental Practices based on ISO 14001:2004 have been identified. The level of understanding of the site staffs on ISO 14001 EMS requirements has been found to be good except for matters concerning Schedule Waste Management. In conclusion, the successful implementation of ISO 14001 EMS mainly depends on staffs‘ understanding.

ISO 14001 ENVIRONMENTAL MANAGEMENT SYSTEMS FOR GOVERNMENT

Science.gov (United States)

This presentation provides an overview of the document, ISO 14001 - A Tool for Supporting Government Environmental Programs and Policies, recently published by USEPA/s Office of Research and Development. It is an informational document, explaining the backjground and development ...

Extremes of shock index predicts death in trauma patients

Directory of Open Access Journals (Sweden)

Stephen R Odom

2016-01-01

Full Text Available Context: We noted a bimodal relationship between mortality and shock index (SI, the ratio of heart rate to systolic blood pressure. Aims: To determine if extremes of SI can predict mortality in trauma patients. Settings and Designs: Retrospective evaluation of adult trauma patients at a tertiary care center from 2000 to 2012 in the United States. Materials and Methods: We examined the SI in trauma patients and determined the adjusted mortality for patients with and without head injuries. Statistical Analysis Used: Descriptive statistics and multivariable logistic regression. Results: SI values demonstrated a U-shaped relationship with mortality. Compared with patients with a SI between 0.5 and 0.7, patients with a SI of 1.3 had an odds ratio of death of 3.1. (95% CI 1.6–5.9. Elevated SI is associated with increased mortality in patients with isolated torso injuries, and is associated with death at both low and high values in patients with head injury. Conclusion: Our data indicate a bimodal relationship between SI and mortality in head injured patients that persists after correction for various co-factors. The distribution of mortality is different between head injured patients and patients without head injuries. Elevated SI predicts death in all trauma patients, but low SI values only predict death in head injured patients.

Performance improvement with ISO 9001:2000: a case of PKOC-II project

Energy Technology Data Exchange (ETDEWEB)

Behera, U.K.; Prasad, K.S.N. [Singareni Collieries Co. Ltd. (India)

2006-07-01

The present study is limited to the study of main step towards ISO 9001:2000 (QMS) development, implementation and improvements of PKOC-II project and the same are discussed. In line with increasing global concern for quality, environmental protection and occupational health and safety, Singareni Collieries Co. Ltd (SCCL) has taken the strategic decision to implement ISO 9001:2000 (QMS), ISO 14001:2004 EMS (environmental management system) and occupational health and safety assessment series 18001:1999 (OHSAS) at the PK OC-II project. This is the first project to implement all three management systems QMS, OHSAS, and EMS, in the Indian coal industry. 25 refs., 12 figs., 2 tabs.

Life cycle analysis. The ISO-standards elaborated in a practical manual; Levenscyclusanalyse. De ISO-normen uitgewerkt in een praktijkgerichte Handleiding

Energy Technology Data Exchange (ETDEWEB)

Guinee, J.B. (ed.) (and others)

2002-04-01

The general aim of the new LCA (life cycle analysis) Guide is to provide a 'cookbook' with operational guidelines for conducting a step-by-step LCA study as justified by a scientific background document based on the ISO Standards for LCA. The different ISO elements and requirements are made operational to what we judged as the 'best available practice' for each step. The new Guide gives guidelines for two levels of sophistication of LCA: a simplified and a detailed level; in addition, optional extensions to the detailed level are provided. The simplified level has been introduced for making faster and cheaper LCAs compared to detailed level LCAs. The simplified level may be good enough for certain applications. The guidelines for detailed LCA fully comply with the ISO standards, while the guidelines given for simplified LCA do not. The new LCA Guide consists of three parts: (1) 'LCA in perspective' provides a general introduction to LCA and includes a discussion on the possibilities and limitations of LCA; (2) consists of two parts, 2a ('Guide') and 2b ('Operational annex'). Part 2a provides an introduction to the procedural design of an LCA project, and guidelines on the best available practice for each of the steps involved in an LCA study, at the two levels of LCA sophistication. Part 2b operationalises most of the guidelines provided in Part 2a and provides the most up-to-date operational models and data associated with the best available practice for the two levels of sophistication, as a separate document. This has been done to facilitate up-dating of these operational elements, most of which are likely to change regularly. Part 3 provides the scientific background to the study, as well as a reasoned justification of all the choices made in designing a best available practice for each phase of an LCA. Next to these books, on-line support is supplied through specific web-sites. For example, a spreadsheet

Molecular mechanisms behind the antimicrobial activity of hop iso-α-acids in Lactobacillus brevis.

Science.gov (United States)

Schurr, Benjamin C; Hahne, Hannes; Kuster, Bernhard; Behr, Jürgen; Vogel, Rudi F

2015-04-01

The main bittering component in beer, hop iso-α-acids, have been characterised as weak acids, which act as ionophores impairing microbial cells' function under acidic conditions as present in beer. Besides medium pH, divalent cations play a central role regarding the efficacy of the antimicrobial effect. The iso-α-acids' non-bitter derivatives humulinic acids can be found in isomerised hop extracts and can be generated during hop storage. Therefore, they have been under investigation concerning their influence on beer sensory properties. This study sketches the molecular mechanism behind iso-α-acids' antimicrobial activity in Lactobacillus (L.) brevis regarding their ionophore activity versus the dependence of the inhibitory potential on manganese binding, and suggests humulinic acids as novel tasteless food preservatives. We designed and synthesised chemically modified iso-α-acids to enhance the basic understanding of the molecular mechanism of antimicrobial iso-α-acids. It could be observed that a manganese-binding dependent transmembrane redox reaction (oxidative stress) plays a crucial role in inhibition. Privation of an acidic hydroxyl group neither erased ionophore activity, nor did it entirely abolish antimicrobial activity. Humulinic acids proved to be highly inhibitory, even outperforming iso-α-acids. Copyright © 2014 Elsevier Ltd. All rights reserved.

An ISO 9001 quality management system in a hospital: bureaucracy or just benefits?

Science.gov (United States)

van den Heuvel, Jaap; Koning, Lida; Bogers, Ad J J C; Berg, Marc; van Dijen, Monique E M

2005-01-01

To describe how The Red Cross Hospital in Beverwijk, The Netherlands implemented an ISO 9000 quality management system throughout the entire organisation, obtained an ISO 9002:1994 and subsequently an ISO 9001:2000 certificate. First, a global implementation plan was written concerning the process obtaining in each department. Once improved, each process was subjected to a procedure, and specific protocols effected. On completion the Quality Manual was put together. Quality management was completed by implementing an internal audit system involving 50 co-workers. A number of advantages are found from using ISO. The focus on patients has been re-established. All processes are identified and subject to continuous improvement. Performance measurements were introduced and give an integrated picture of results. Measurements subsequently lead to improvement of quality of care and to quality system improvements. The documentation system serves the organization's needs without leading to bureaucracy. Positive effects on patient safety could be demonstrated compared with ten other hospitals. Given the need for adequate quality management tools in health care and the need for demonstrating quality, the positive effects reported in this article show how ISO is expected to become more prevalent in health-care organisations.

KSC Center Director Bridges addresses the audience at an ISO 9001 certification ceremony

Science.gov (United States)

1998-01-01

Center Director Roy Bridges speaks to KSC employees at the ISO certification ceremony held at the Training Auditorium. Bridges was presented an ISO 9001 certificate and plaque awarded to KSC by Det Norske Veritas (DNV), Inc., an international ISO certification organization. ISO 9001 comprises the most detailed, comprehensive set of standard requirements for quality programs established by the International Standards Organization. The presentation followed a successful independent audit by DNV of the KSC Management System in May of this year. The third-party auditors examined about 20 elements of KSC's system, including management responsibility, design control, documentation, test and inspection, and corrective action procedures. DNV found that KSC met or exceeded the stringent quality standards in all areas. KSC will use this certification as a tool to improve an already world- class team. All NASA centers are required by NASA Administrator Daniel S. Goldin to be ISO 9001 registered by September 1999. NASA is the first federal agency to seek the quality certification. Next to Bridges is Heidi Hollingsworth, with the Center for Independent Living, who uses American Sign Language for any hearing-impaired employees in the audience.

Complementing network security to the ISO/IEC 27000 standard

OpenAIRE

Alila, Patrick

2007-01-01

I syfte att öppna upp nya affärsmöjligheter för informationssäkerhetsföretaget Secure State AB, har detta arbete bedrivits för att komplettera företagets nuvarande standard för informationssäkerhetsarbete med ytterligare nätverkssäkerhet. Krav på slutresultatet var att dokumentet eller standarden skulle kunna komplettera ISO 27000, samt vara kostnadseffektivt. Efter en undersökning av den nämnda standarden konstaterades att enbart ISO 27000 i sig inte är ett fullgott verktyg för nätverkssäker...

Implementation of ISO 22000 in Romanian Companies: Motivations, Difficulties and Key Benefits

Directory of Open Access Journals (Sweden)

Carmen Păunescu

2018-02-01

Full Text Available The development of well-designed food safety management systems that take into consideration the potential risks and threats to an organization and their associated impacts to business operations should be a key goal for each organization operating in the food supply chain. This study provides quantitative empirical evidence about the motivations for implementing a food safety management system based on ISO 22000. By employing factor analysis and multiple linear regression, it analyses the benefits that the ISO 22000 certified companies gained through certification, as well as the main constraints that may prevent the adoption of the standard in the food industry. The survey is based on a sample of Romanian companies distributed at all levels of the food chain, but mainly at the production level. While there exist external pressures that lead companies to adopt a food safety management system based on ISO 22000, the motivations that are most relevant in this decision are generally internal in nature. The results of our study identify three major benefits of ISO 22000 certification: food safety improvement and provision of safer products, reduction of illness and other risks arising from food and improvement of consumers’ confidence. Also, it points out three constraints limiting the dissemination and use of ISO 22000: employees’ qualification, costs associated with food safety management system implementation and legal requirements.

Adsorption and separation of n/iso-pentane on zeolites: A GCMC study.

Science.gov (United States)

Fu, Hui; Qin, Hansong; Wang, Yajun; Liu, Yibin; Yang, Chaohe; Shan, Honghong

2018-03-01

Separation of branched chain hydrocarbons and straight chain hydrocarbons is very important in the isomerization process. Grand canonical ensemble Monte Carlo simulations were used to investigate the adsorption and separation of iso-pentane and n-pentane in four types of zeolites: MWW, BOG, MFI, and LTA. The computation of the pure components indicates that the adsorption capacity is affected by physical properties of zeolite, like pore size and structures, and isosteric heat. In BOG, MFI and LTA, the amount of adsorption of n-pentane is higher than iso-pentane, while the phenomenon is contrary in MWW. For a given zeolite, a stronger adsorption heat corresponds to a higher loading. In the binary mixture simulations, the separation capacity of n-and iso-pentane increases with the elevated pressure and the increasing iso-pentane composition. The adsorption mechanism and competition process have been examined. Preferential adsorption contributions prevail at low pressure, however, the size effect becomes important with the increasing pressure, and the relatively smaller n-pentane gradually competes successfully in binary adsorption. Among these zeolites, MFI has the best separation performance due to its high shape selectivity. This work helps to better understand the adsorption and separation performance of n- and iso-pentane in different zeolites and explain the relationship between zeolite structures and adsorption performance. Copyright © 2017 Elsevier Inc. All rights reserved.

ISO 13485 a complete guide to quality management in the medical device industry

CERN Document Server

Abuhav, Itay

2011-01-01

Although complex and lengthy, the process of certification for the ISO 13485 can be easily mastered using the simple method outlined in ISO 13485: A Complete Guide to Quality Management in the Medical Device Industry. Written by an experienced industry professional, this practical book provides a complete guide to the ISO 13485 Standard certification for medical device manufacturing. Filled with examples drawn from the author's experience and spanning different sectors and fields of the medical device industry, the book translates the extra ordinary requirements and objectives of the standard

WHAT IS THE PURPOSE OF ISO 9000 CERTIFICATION? EMPIRICAL EVIDENCE FROM FRENCH MICRO-DATA

Directory of Open Access Journals (Sweden)

Sanja Pekovic

2008-03-01

Full Text Available The ISO 9000 certification is often associated with quality approach, and activities that are by now widely diffused throughout business. The statistical research shows that quality management practice is one of the most utilized tools because in 1997, more than a third of industrial firms have received the quality certification. Regarded like an investment in a diploma, investment in quality norms can at the same time be a function of improvement of the company's competence and can also make a signal on the market. In our research, we want to understand those two functions of the ISO 9000 certification and to see how they act in the company and on the market. The paper will explore two possible functions of the certification and will analysis the consequences for the firms. The research will use national statistics sources and case research for the empirical investigation to identify the internal characteristics of ISO 9000 adoption. Also, it will use C.O.I database (Organizational Changes and Computerization of 1997 and E.A.E. database (Annual Survey of Industry. In this research, the empirical results show that ISO certification has a part of increase the level of firm's export. Moreover, the firms that have recently adopted the ISO certification invest more in quality than those that have adopted ISO certification more ago. The results show that the firms from same sector of activity "are pushed" to adopt certification. At the end, the results show that, the probability that the firm adopt ISO certification increase with firm's size.

Diseño e implantación de un sistema integrado de calidad y medio ambiente (ISO 9001: 2008 e ISO14001:2004) en una empresa de obra civil

OpenAIRE

Campano Calleja, Juan Manuel

2012-01-01

El Proyecto Fin de Carrera tiene como objetivos el diseño, desarrollo e implantación de un Sistema de Gestión Integrado de Calidad y de Medio Ambiente según las normas ISO 9001:2008 e ISO 14001:2004 para una empresa ficticia llamada MID EXCAVACIONES S.L.

Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping

DEFF Research Database (Denmark)

Augustsson, Per; Karlsen, Jonas Tobias; Su, Hao-Wei

2016-01-01

Mechanical phenotyping of single cells is an emerging tool for cell classification, enabling assessment of effective parameters relating to cells' interior molecular content and structure. Here, we present iso-acoustic focusing, an equilibrium method to analyze the effective acoustic impedance...... of single cells in continuous flow. While flowing through a microchannel, cells migrate sideways, influenced by an acoustic field, into streams of increasing acoustic impedance, until reaching their cell-type specific point of zero acoustic contrast. We establish an experimental procedure and provide...... theoretical justifications and models for iso-acoustic focusing. We describe a method for providing a suitable acoustic contrast gradient in a cell-friendly medium, and use acoustic forces to maintain that gradient in the presence of destabilizing forces. Applying this method we demonstrate iso-acoustic...

Study on the Evolution of the Current ISO Certifications in Romania

Directory of Open Access Journals (Sweden)

Teodor Socaciu

2013-06-01

Full Text Available To increase the efficiency and effectiveness of processes within an organization, ISO standards can help both large enterprises and small companies (SMEs, both in industrialized and in developing countries offering solutions and bringing considerable advantages in almost all existing fields. ISO certification brings a set of measures in the areas of an organization, be it about quality, environmental safety, food or protection and safety of personnel, this certification brings benefits both in the current processes and more importantly, the future development plans. In this paper, graphs showing the distributions of increasing certification, demonstrate that more and more companies in Romania have realized that, only implementing and certifying ISO standards, they will be successful in domestic and international market in terms of competition, in particular against European companies.

Saturated hydraulic conductivity model computed from bimodal water retention curves for a range of New Zealand soils

Directory of Open Access Journals (Sweden)

J. A. P. Pollacco

2017-06-01

Full Text Available Descriptions of soil hydraulic properties, such as the soil moisture retention curve, θ(h, and saturated hydraulic conductivities, Ks, are a prerequisite for hydrological models. Since the measurement of Ks is expensive, it is frequently derived from statistical pedotransfer functions (PTFs. Because it is usually more difficult to describe Ks than θ(h from pedotransfer functions, Pollacco et al. (2013 developed a physical unimodal model to compute Ks solely from hydraulic parameters derived from the Kosugi θ(h. This unimodal Ks model, which is based on a unimodal Kosugi soil pore-size distribution, was developed by combining the approach of Hagen–Poiseuille with Darcy's law and by introducing three tortuosity parameters. We report here on (1 the suitability of the Pollacco unimodal Ks model to predict Ks for a range of New Zealand soils from the New Zealand soil database (S-map and (2 further adaptations to this model to adapt it to dual-porosity structured soils by computing the soil water flux through a continuous function of an improved bimodal pore-size distribution. The improved bimodal Ks model was tested with a New Zealand data set derived from historical measurements of Ks and θ(h for a range of soils derived from sandstone and siltstone. The Ks data were collected using a small core size of 10 cm diameter, causing large uncertainty in replicate measurements. Predictions of Ks were further improved by distinguishing topsoils from subsoil. Nevertheless, as expected, stratifying the data with soil texture only slightly improved the predictions of the physical Ks models because the Ks model is based on pore-size distribution and the calibrated parameters were obtained within the physically feasible range. The improvements made to the unimodal Ks model by using the new bimodal Ks model are modest when compared to the unimodal model, which is explained by the poor accuracy of measured total porosity. Nevertheless, the new bimodal

Saturated hydraulic conductivity model computed from bimodal water retention curves for a range of New Zealand soils

Science.gov (United States)

Pollacco, Joseph Alexander Paul; Webb, Trevor; McNeill, Stephen; Hu, Wei; Carrick, Sam; Hewitt, Allan; Lilburne, Linda

2017-06-01

Descriptions of soil hydraulic properties, such as the soil moisture retention curve, θ(h), and saturated hydraulic conductivities, Ks, are a prerequisite for hydrological models. Since the measurement of Ks is expensive, it is frequently derived from statistical pedotransfer functions (PTFs). Because it is usually more difficult to describe Ks than θ(h) from pedotransfer functions, Pollacco et al. (2013) developed a physical unimodal model to compute Ks solely from hydraulic parameters derived from the Kosugi θ(h). This unimodal Ks model, which is based on a unimodal Kosugi soil pore-size distribution, was developed by combining the approach of Hagen-Poiseuille with Darcy's law and by introducing three tortuosity parameters. We report here on (1) the suitability of the Pollacco unimodal Ks model to predict Ks for a range of New Zealand soils from the New Zealand soil database (S-map) and (2) further adaptations to this model to adapt it to dual-porosity structured soils by computing the soil water flux through a continuous function of an improved bimodal pore-size distribution. The improved bimodal Ks model was tested with a New Zealand data set derived from historical measurements of Ks and θ(h) for a range of soils derived from sandstone and siltstone. The Ks data were collected using a small core size of 10 cm diameter, causing large uncertainty in replicate measurements. Predictions of Ks were further improved by distinguishing topsoils from subsoil. Nevertheless, as expected, stratifying the data with soil texture only slightly improved the predictions of the physical Ks models because the Ks model is based on pore-size distribution and the calibrated parameters were obtained within the physically feasible range. The improvements made to the unimodal Ks model by using the new bimodal Ks model are modest when compared to the unimodal model, which is explained by the poor accuracy of measured total porosity. Nevertheless, the new bimodal model provides an

75 FR 16096 - New England Power Generators Association Inc., Complainant v. ISO New England Inc., Respondent...

Science.gov (United States)

2010-03-31

...-787-000] New England Power Generators Association Inc., Complainant v. ISO New England Inc., Respondent; ISO New England Inc. and New England Power Pool; Notice of Complaint March 24, 2010. Take notice... Inc. (Complainant) filed a formal complaint against ISO New England Inc. (Respondent) alleging that...

ISO19770-1:2012 SAM process guidance

CERN Document Server

Canavan, Rory

2012-01-01

The pocket guide offers a concise summary of the principles of software asset management as conveyed by ISO 19770-1: 2012, and provides advice and guidance on how to kick-start your own SAM programme - something the Standard alone doesn't offer.

Infra-slow oscillation (ISO of the pupil size of urethane-anaesthetised rats.

Directory of Open Access Journals (Sweden)

Tomasz Blasiak

Full Text Available Multiplicity of oscillatory phenomena in a range of infra-slow frequencies (<0.01 Hz has been described in mammalian brains at different levels of organisation. The significance and manifestation in physiology and/or behaviour of many brain infra-slow oscillations (ISO remain unknown. Examples of this phenomenon are two types of ISO observed in the brains of urethane-anaesthetised rats: infra-slow, rhythmic changes in the rate of action potential firing in a few nuclei of the subcortical visual system and a sleep-like cycle of activation/deactivation visible in the EEG signal. Because both of these rhythmic phenomena involve brain networks that can influence autonomic nervous system activity, we hypothesised that these two brain ISOs can be reflected by rhythmic changes of pupil size. Thus, in the present study, we used simultaneous pupillography and ECoG recording to verify the hypothesised existence of infra-slow oscillations in the pupil size of urethane-anaesthetised rats. The obtained results showed rhythmic changes in the size of the pupils and rhythmic eyeball movements in urethane-anaesthetised rats. The observed rhythms were characterised by two different dominant components in a range of infra-slow frequencies. First, the long component had a period of ≈ 29 minutes and was present in both the irises and the eyeball movements. Second, the short component had a period of ≈ 2 minutes and was observed only in the rhythmic constrictions and dilations of the pupils. Both ISOs were simultaneously present in both eyes, and they were synchronised between the left and right eye. The long ISO component was synchronised with the cyclic alternations of the brain state, as revealed by rhythmic changes in the pattern of the ECoG signal. Based on the obtained results, we propose a model of interference of ISO present in different brain systems involved in the control of pupil size.

Investigation of heterogeneous asymmetric dihydroxylation over OsO{sub 4}-(QN){sub 2}PHAL catalysts of functionalized bimodal mesoporous silica with ionic liquid

Energy Technology Data Exchange (ETDEWEB)

Qiu, Shenjie [College of Environmental and Energy Engineering, Beijing University of Technology, Beijing 100124 (China); Sun, Jihong, E-mail: jhsun@bjut.edu.cn [College of Environmental and Energy Engineering, Beijing University of Technology, Beijing 100124 (China); Li, Yuzhen; Gao, Lin [College of Environmental and Energy Engineering, Beijing University of Technology, Beijing 100124 (China)

2011-08-15

Highlights: {yields} Functionalized bimodal mesoporous silica with MTMSPIm{sup +}Cl{sup -}. {yields} Mesoporous catalyst immobilized with OsO{sub 4}-(QN){sub 2}PHAL. {yields} Catalysts for asymmetric dihydroxylation reaction with high yield and enatioselectivity. {yields} Recyclable catalysts. -- Abstract: A novel synthesis of the functionalized bimodal mesoporous silica with ionic liquid (FBMMs) was performed. After grafting 1-methyl-3-(trimethoxysilyl)propylimidazolium chloride onto the surface of bimodal mesoporous silicas, 1,4-bis(9-O-quininyl)phthalazine ((QN){sub 2}-PHAL) and K{sub 2}Os(OH){sub 4}.2H{sub 2}O were immobilized onto the modified FBMMs by adsorption or ionic exchange methods, and then, the asymmetric dihydroxylation reaction was carried out by using solid catalysts. Techniques such as X-ray diffraction, Fourier Transform Infrared spectroscopy, N{sub 2} adsorption and desorption were employed to characterize their structure and properties. The results showed that the mesoporous ordering degree of bimodal mesoporous silica decreased after functionalization and immobilization of OsO{sub 4}-(QN){sub 2}PHAL. Being very effective in asymmetric dihydroxylation with high yield and enantioselectivity, the prepared heterogeneous solid catalyst could be recycled for five times with little loss of enantioselectivity, with comparison of those results obtained in homophase system. Moreover, the effect of Osmium catalyst on asymmetric dihydroxylation was investigated.

ITIL and ISO/IEC 20000 a practical handbook

CERN Document Server

Hernandez, Alex

2012-01-01

The purpose of this publication is to provide your organization with a pragmatic approach to effectively implementing service management, incorporating practices from the ITIL framework and the ISO/IEC 20000 standard.

[Quality management according to DIN EN ISO 9001 at a university eye hospital].

Science.gov (United States)

Schönherr, U; Händel, A; Naumann, G O

2001-02-01

Quality assurance is an integral part of modern microsurgical ophthalmology. Health care laws also mandate overall quality management. In recent years we have standardized the preexisting features of quality management according DIN EN ISO 9001 and have integrated previously missing features. Establishing quality management according to ISO 9001 is possible even at a university eye hospital and department of ophthalmology. Certification according to ISO 9001 specifications was granted in April 1999. The major difficulty was in translating industrial norms to the context of an eye hospital. It was also difficult to overcome skepticism towards quality-assurance measures that lie beyond ophthalmological quality control. It is useful and feasible to establish a quality management system at German university eye hospitals and departments of ophthalmology. Certification according to ISO 9001 is one possibility to make a quality management system transparent and evaluable both inside and outside the hospital.

Aspirin provocation increases 8-iso-PGE2 in exhaled breath condensate of aspirin-hypersensitive asthmatics.

Science.gov (United States)

Mastalerz, Lucyna; Januszek, Rafał; Kaszuba, Marek; Wójcik, Krzysztof; Celejewska-Wójcik, Natalia; Gielicz, Anna; Plutecka, Hanna; Oleś, Krzysztof; Stręk, Paweł; Sanak, Marek

2015-09-01

Isoprostanes are bioactive compounds formed by non-enzymatic oxidation of polyunsaturated fatty acids, mostly arachidonic, and markers of free radical generation during inflammation. In aspirin exacerbated respiratory disease (AERD), asthmatic symptoms are precipitated by ingestion of non-steroid anti-inflammatory drugs capable for pharmacologic inhibition of cyclooxygenase-1 isoenzyme. We investigated whether aspirin-provoked bronchoconstriction is accompanied by changes of isoprostanes in exhaled breath condensate (EBC). EBC was collected from 28 AERD subjects and 25 aspirin-tolerant asthmatics before and after inhalatory aspirin challenge. Concentrations of 8-iso-PGF2α, 8-iso-PGE2, and prostaglandin E2 were measured using gas chromatography/mass spectrometry. Leukotriene E4 was measured by immunoassay in urine samples collected before and after the challenge. Before the challenge, exhaled 8-iso-PGF2α, 8-iso-PGE2, and PGE2 levels did not differ between the study groups. 8-iso-PGE2 level increased in AERD group only (p=0.014) as a result of the aspirin challenge. Urinary LTE4 was elevated in AERD, both in baseline and post-challenge samples. Post-challenge airways 8-iso-PGE2 correlated positively with urinary LTE4 level (p=0.046), whereas it correlated negatively with the provocative dose of aspirin (p=0.027). A significant increase of exhaled 8-iso-PGE2 after inhalatory challenge with aspirin was selective and not present for the other isoprostane measured. This is a novel finding in AERD, suggesting that inhibition of cyclooxygenase may elicit 8-iso-PGE2 production in a specific mechanism, contributing to bronchoconstriction and systemic overproduction of cysteinyl leukotrienes. Copyright © 2015 Elsevier Inc. All rights reserved.

Lean environmental management integration system for sustainability of ISO 14001:2004 standard implementation

Directory of Open Access Journals (Sweden)

Perumal Puvanasvaran

2014-10-01

Full Text Available Purpose: The purpose of this study is to present a model for integrating Lean Principles with ISO 14001 Environmental Management System.Design/methodology/approach: To achieve the objective of the study, the methodology used in this study is based on preliminary literature review of ISO 14001 standards and Lean Principles as well as certain case reports from various proponents and authors of ISO 14001 and Lean as noted in various articles and journals and some books.Findings and Originality/value: The findings of this study are a new model called Lean Environmental Management Integration System (LEMIS has been developed and leads to the creation of these measurement standards for evaluating the organization, making its environmental efforts more realistic, focused and attainable.Research limitations/implications: Future research should be conducted case studies in this direction are required to be conducted for examining the feasibility of amalgamation and implementing ISO 14001:2004 standards with the philosophy of Lean Principles to enable the achievement of world class standards.Practical implications: This model helps to eliminate any wasteful processes in the organization’s implementation of the ISO 14001 standard thus leading to higher environmental performance.  Integrating the standard with Lean principles through LEMIS model helps to specify these performance measures making the standard achieve sustainability and continual improvement.Originality/value: This study presents a unique approach of integrating the two main models, namely Lean Principles and ISO 14001 Environmental Management System, as a single framework benefiting contemporary organizations.

Diseño e implantación de una oficina técnica según normativa ISO 9001:2000 e ISO 14001:2004, en una empresa del sector aeronautico

OpenAIRE

Hucha Sierra, Antonio

2006-01-01

El proyecto describirá dos procesos fundamentalmente, el diseño de la empresa de SITA enfocada hacia los Estudios de Ingeniería, y la implantación y certificación de un Sistema de Gestión de Calidad y Medioambiente, según las normativas ISO 9001:2000 e ISO 14001:2004.

Implementation Of ISO 9000 Quality Management System Within The Manufacturing And Service Industry Of Ivory Coast

Directory of Open Access Journals (Sweden)

Borget Alfred Anoye

2015-08-01

Full Text Available Abstract The objective of this paper was to present the factors that impede the implementation of ISO 9000 QMS within the manufacturing and service Industry of Ivory Coast. It wasnt the intention of the author to provide detailed strategies for the readers to implement ISO 9000. It was an effort to present the relationship if any between the lack of ISO 9000 adoption and the perception of Ivoirians business organization leaders. For that purpose five research questions were associated with this study. The population for this study was all non-ISO certified business organizations in both public and private sector and was physically located in Ivory Coast. The population sample for this study was the 5044 members of the Chambre de Commerce et dIndustrie de Cote dIvoire CCI from which the author utilized the sample size of 60 business organizations randomly selected. This study utilized a survey questionnaire of face to face interview as data collection method. The survey questionnaire contained thirty three 33 questions organized in six parts and was proposed to 60 business organizations leaders. The result showed that business organization leaders in Ivory Coast were aware of the ISO 900 QMS but do not have enough knowledge on the ISO 9000 QMS implementation and certification. This could be due to the poor job done by CODIMORM the local national bureau of standards as a source of information. However it was found that business organization leaders in Ivory Coast intended to pursue and obtain ISO 9000 QMS certification. With respect to perceived benefits they indicated customer satisfaction improvement as the most important benefit that ISO 9000 QMS certification could bring to their general management activities. With respect to perceived improvements they selected quality of productsservices as the most important improvement that ISO 9000 QMS implementation and certification could help to achieve. Overall business organization leaders in Ivory

On the new ISO guide on risk management terminology

International Nuclear Information System (INIS)

Aven, Terje

2011-01-01

A new ISO guide on risk management terminology has recently been issued. The guide provides basic vocabulary for developing a common understanding of risk assessment and risk management concepts and terms among organisations and functions, and across different application areas. It provides the foundation of, for example, the ISO 31000 standard on risk management. The guide strongly influences the risk assessment and risk management field, and its quality is thus of utmost importance. In this paper a critical review of the guide is conducted. We argue that the guide fails in several ways in producing consistent and meaningful definitions of many of the key concepts covered. A main focus is placed on the risk concept, which is defined as the effect of uncertainty on objectives, but also many other definitions are looked into, including probability, vulnerability, hazard, risk identification and risk description. Examples are used to illustrate the problems and show how they can be rectified. Although the focus is on the ISO guide, the discussion is to a large extent general. The overall aim of the paper is to contribute to the further development of the area of risk assessment and risk management by strengthening its conceptual basis.

Relationship between platelet and urinary 8-Iso-PGF2α levels in subjects with different degrees of NOX2 regulation.

Science.gov (United States)

Carnevale, Roberto; Iuliano, Luigi; Nocella, Cristina; Bartimoccia, Simona; Trapè, Stefano; Russo, Roberta; Gentile, Maria Cristina; Cangemi, Roberto; Loffredo, Lorenzo; Pignatelli, Pasquale; Violi, Francesco

2013-06-14

Urinary 8-iso-PGF2α, a marker of oxidative stress, is influenced by the activation of NOX2. It is unclear if platelets 8-iso-PGF2α contribute to urinary 8-iso-PGF2α. In a cross-sectional study, platelet, urinary, and serum 8-iso-PGF2α were determined in subjects with downregulation (X-linked chronic granulomatous disease [X-CGD], n=25) and upregulation (type II diabetic patients [T2D], n=121) of NOX2 and 153 controls matched for sex and age. In diabetic patients (n=18), the above variables were repeated before and after 7 days treatment with 100 mg/day aspirin or 100 mg/day aspirin plus 40 mg/day atorvastatin. In vitro study was performed to see the contribution of blood cells to serum 8-iso-PGF2α. Compared with controls, X-CGD patients had lower platelet, serum, and urinary 8-iso-PGF2α values; conversely, diabetic patients had higher values of 8-iso-PGF2α compared with controls. Urinary 8-iso-PGF2α significantly correlated with both platelet and serum 8-iso-PGF2α in the 2 cohorts. A parallel increase of platelet, serum, and urinary 8-iso-PGF2α by aspirin and a parallel decrease by aspirin plus atorvastatin were detected in the interventional study. In vitro study demonstrated that platelets contribute to 37% of serum 8-iso-PGF2α and that only 13% of it is of extravascular origin. The study suggests that NOX2 contributes to the formation of 8-iso-PGF2α in both platelets and urine. The direct correlation between platelet and urinary 8-iso-PGF2α suggests that, at least partly, urinary 8-iso-PGF2α reflects platelet 8-iso-PGF2α production. Analysis of serum 8-iso-PGF2α may represent a novel tool to investigate the production of 8-iso-PGF2α by blood cells including platelets. URL: ClinicalTrials.gov. Unique Identifier: NCT01250340.

ISO/IEC 38500 the IT governance standard

CERN Document Server

Calder, Alan

2008-01-01

The emergence of ISO/IEC 38500 - the international standard for the corporate governance of information and communication technology - puts boards around the world in a position from which they can take effective action to apply core governance principles to their information and communication technology.

X(3872) and Its Iso-Triplet Partners

OpenAIRE

Kunihiko, TERASAKI; Yukawa Institute for Theoretical Physics, Kyoto University:Institute for Theoretical Physics, Kanazawa University

2012-01-01

Decays of X(3872) and its partners as hidden-charm axial-vector tetra-quark mesons are studied. As the result, it is seen that the iso-triplet partners of X(3872) can be broad, and therefore, higher statistics will be needed to find them.

New ISO standards for hearing protectors (A)

DEFF Research Database (Denmark)

Poulsen, Torben

2000-01-01

Working Group 17 under ISO/TC43/SC1 deals with measurement of hearing protector attenuation. WG17 is presently involved in revision of the present 4869-1 standard (especially sound field requirements and reproducibility estimations) and formulation of a new standard where inexperienced hearing...

Conformance on Quality Management System of One State College in the Philippines as Basis for ISO Certification

Directory of Open Access Journals (Sweden)

Romulo T. Sisno

2017-11-01

Full Text Available This study sought to determine the quality management system of the Northern Negros State College of Science and Technology (NONESCOST as basis for International Organization for Standardization (ISO Certification. The descriptive method of research was used in this study. It utilized the ISO 9001:2008 Quality Management System Requirements Checklist and the Questionnaires on the Attitudes towards ISO 9001. The study utilized a descriptive research design.. Findings revealed that the attitude of administrators, teaching personnel and administrative staff’ towards ISO 9001 in terms of benefits, challenges, recommendations and standards did not differ significantly. Findings further revealed that the employees have mostly positive perceptions of ISO 9001, resulting in positive attitudes in the workplace. Findings also revealed that the extent of conformance to the ISO 9001:2008 (QMS Requirements in the areas of Quality Management System, Management Responsibility, Resource Management, Product Realization and Measurement, Analysis and Improvement was perceived by the respondents to be minor non-conformance. It implies that fulfillment to the ISO 9001:2008 Requirements was only satisfactory

Why did ISO 9001:2008 system fail to deliver?

Science.gov (United States)

Langford, Melvyn

2014-02-01

This article is based on an actual investigation undertaken, and summarises the subsequent report's findings and observations. It has been anonymised for obvious reasons. In May 2013 an analysis was undertaken by a multidisciplinary team that compared an NHS Trust estates department's managerial systems against the NHS national recommendations. The conclusions stated that: 'There was a systemic failure across a large number of topics generating intolerable/substantial risks to the organisation, its staff, and patients; this despite the department's managerial systems being accredited to the International Standard ISO 9001:2008'. The natural question raised when presented with this demonstrable and auditable evidence was: 'Why did the ISO 9001:2008 system fail?'

Shikonin ameliorates isoproterenol (ISO)-induced myocardial damage through suppressing fibrosis, inflammation, apoptosis and ER stress.

Science.gov (United States)

Yang, Jun; Wang, Zhao; Chen, Dong-Lin

2017-09-01

Shikonin, isolated from the roots of herbal plant Lithospermum erythrorhizon, is a naphthoquinone. It has been reported to exert beneficial anti-inflammatory effects and anti-oxidant properties in various diseases. Isoproterenol (ISO) has been widely used to establish cardiac injury in vivo and in vitro. However, shikonin function in ISO-induced cardiac injury remains uncertain. In our study, we attempted to investigate the efficiency and possible molecular mechanism of shikonin in cardiac injury treatment induced by ISO. In vivo, C57BL6 mice were subcutaneously injected with 5mg/kg ISO to induce heart failure. And mice were given a gavage of shikonin (2 or 4mg/kg/d, for four weeks). Cardiac function, fibrosis indices, inflammation response, apoptosis and endoplasmic reticulum (ER) stress were calculated. Pathological alterations, fibrosis-, inflammation-, apoptosis- and ER stress-related molecules were examined. In ISO-induced cardiac injury, shikonin significantly ameliorated heart function, decreased myocardial fibrosis, suppressed inflammation, attenuated apoptosis and ER stress through impeding collagen accumulation, Toll like receptor 4/nuclear transcription factor κB (TLR4/NF-κB), Caspase-3 and glucose-regulated protein 78 (GRP78) signaling pathways activity, relieving heart failure in vivo. Also, in vitro, shikonin attenuated ISO-induced cardiac muscle cells by reducing fibrosis, inflammation, apoptosis and ER stress. Our findings indicated that shikonin treatment attenuated ISO-induced heart injury, providing an effective therapeutic strategy for heart failure treatment for future. Copyright © 2017. Published by Elsevier Masson SAS.

[Nine-Year Experience after ISO 15189 Acquisition, How Successful was It? Focusing on the Results of Interviews and Questionnaires].

Science.gov (United States)

Fujimoto, Kazumitsu; Asai, Noriaki; Nakajima, Yoshinaga; Inoue, Kaoru

2015-11-01

Our laboratory, for the purpose of Quality Management System (QMS) improvement, acquired ISO 15189:2003 accreditation 9 years ago and completed the renewal to ISO 15189:2012 last year. In this study, we reviewed the efficacy of ISO 15189 based on an analysis of laboratory director's and managers' opinions. We could realize QMS improvement through the proactive implementation of preventive and corrective actions, and also the continuous implementation of education and delivery by means of reviewing the interview records of ISO 15189:2012 renewal with the laboratory director. All answers to the questionnaire obtained from managers with regard to the advantages of ISO 15189 acquisition agreed with the purpose of ISO 15189. From these results, we concluded that ISO 15189 acquisition was successful for QMS improvement. [Review].

Management system quality of service radio physics and RR. ISO 9001

International Nuclear Information System (INIS)

Gil Agudo, A.; Torres Donaire, J.; Jimenez, J. C.; Carrascosa Fernandez, C.; Arjona Gutierrez, J.

2011-01-01

One of the tool increasingly deployed for the optimization of the procedures is the process management system according to a Quality Management. Likewise, for specific areas, such as central services within large institutions such as the General Hospitals of the systems of quality management is the most widely used ISO 9001. We describe in this paper our experience in implementing the system ISO 9001 in our Department of Radio physics and Radiation Protection (SRFPR).

ncISO Facilitating Metadata and Scientific Data Discovery

Science.gov (United States)

Neufeld, D.; Habermann, T.

2011-12-01

Increasing the usability and availability climate and oceanographic datasets for environmental research requires improved metadata and tools to rapidly locate and access relevant information for an area of interest. Because of the distributed nature of most environmental geospatial data, a common approach is to use catalog services that support queries on metadata harvested from remote map and data services. A key component to effectively using these catalog services is the availability of high quality metadata associated with the underlying data sets. In this presentation, we examine the use of ncISO, and Geoportal as open source tools that can be used to document and facilitate access to ocean and climate data available from Thematic Realtime Environmental Distributed Data Services (THREDDS) data services. Many atmospheric and oceanographic spatial data sets are stored in the Network Common Data Format (netCDF) and served through the Unidata THREDDS Data Server (TDS). NetCDF and THREDDS are becoming increasingly accepted in both the scientific and geographic research communities as demonstrated by the recent adoption of netCDF as an Open Geospatial Consortium (OGC) standard. One important source for ocean and atmospheric based data sets is NOAA's Unified Access Framework (UAF) which serves over 3000 gridded data sets from across NOAA and NOAA-affiliated partners. Due to the large number of datasets, browsing the data holdings to locate data is impractical. Working with Unidata, we have created a new service for the TDS called "ncISO", which allows automatic generation of ISO 19115-2 metadata from attributes and variables in TDS datasets. The ncISO metadata records can be harvested by catalog services such as ESSI-labs GI-Cat catalog service, and ESRI's Geoportal which supports query through a number of services, including OpenSearch and Catalog Services for the Web (CSW). ESRI's Geoportal Server provides a number of user friendly search capabilities for end users

Development of international standards for surface analysis by ISO technical committee 201 on surface chemical analysis

International Nuclear Information System (INIS)

Powell, C.J.

1999-01-01

Full text: The International Organization for Standardization (ISO) established Technical Committee 201 on Surface Chemical Analysis in 1991 to develop documentary standards for surface analysis. ISO/TC 201 met first in 1992 and has met annually since. This committee now has eight subcommittees (Terminology, General Procedures, Data Management and Treatment, Depth Profiling, AES, SIMS, XPS, and Glow Discharge Spectroscopy (GDS)) and one working group (Total X-Ray Fluorescence Spectroscopy). Each subcommittee has one or more working groups to develop standards on particular topics. Australia has observer-member status on ISO/TC 201 and on all ISO/TC 201 subcommittees except GDS where it has participator-member status. I will outline the organization of ISO/TC 201 and summarize the standards that have been or are being developed. Copyright (1999) Australian X-ray Analytical Association Inc

PENGEMBANGAN DAN ANALISIS KUALITAS APLIKASI PENILAIAN E-LEARNING SMK BERBASIS ISO 19796-1 DI YOGYAKARTA

Directory of Open Access Journals (Sweden)

Ahmad Faiq Abror

2016-03-01

Full Text Available Penelitian ini bertujuan untuk: (1 menghasilkan aplikasi penilaian e-learning Sekolah Menengah Kejuruan (SMK berbasis ISO 19796-1 yang dapat digunakan untuk mengevaluasi e-learning SMK di Yogyakarta menggunakan teknik Analitycal Hierarchy Process (AHP dengan metode agregasi arithmetric mean dan geometric mean, (2 menguji kualitas aplikasi dengan menggunakan strandar ISO 9126. Penelitian ini merupakan penelitian Research and Development (R&D. Proses pengembangan aplikasi menggunakan metode  Software Development Life Cycle (SDLC dengan model Waterfall. Selanjutnya pada proses pengujian kualitas aplikasi menggunakan standar ISO 9126 yang terdiri atas aspek functionality, reliability, efficiency, maintainability, usability, dan portability. Hasil penelitian menunjukkan bahwa aplikasi penilaian e-learning SMK berdasarkan ISO 19796-1 telah berhasil dikembangkan menggunakan metode Software Development Life Cycle (SDLC dengan model waterfall. Selanjutnya hasil dari analisis kualitas aplikasi menggunakan standar ISO 9126 menunjukkan bahwa aplikasi mempunyai hasil rata-rata sangat baik dan layak digunakan untuk penilaian kualitas e-learning SMK.

78 FR 38027 - ISO New England Inc.; Notice of Initiation of Proceeding and Refund Effective Date

Science.gov (United States)

2013-06-25

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL13-72-000] ISO New England... III.A.15 of Appendix A of ISO New England Inc.'s existing tariff. Dominion Energy Marketing, Inc. and ISO New England Inc., 143 FERC ] 61,233 (2013). The refund effective date in Docket No. EL13-72-000...

Quality control with R an ISO standards approach

CERN Document Server

Cano, Emilio L; Prieto Corcoba, Mariano

2015-01-01

Presenting a practitioner's guide to capabilities and best practices of quality control systems using the R programming language, this volume emphasizes accessibility and ease-of-use through detailed explanations of R code as well as standard statistical methodologies. In the interest of reaching the widest possible audience of quality-control professionals and statisticians, examples throughout are structured to simplify complex equations and data structures, and to demonstrate their applications to quality control processes, such as ISO standards. The volume balances its treatment of key aspects of quality control, statistics, and programming in R, making the text accessible to beginners and expert quality control professionals alike. Several appendices serve as useful references for ISO standards and common tasks performed while applying quality control with R.

Spatial attention triggered by unimodal, crossmodal, and bimodal exogenous cues: a comparison of reflexive orienting mechanisms

NARCIS (Netherlands)

Santangelo, Valerio; van der Lubbe, Robert Henricus Johannes; Belardinelli, Marta Olivetti; Postma, Albert

The aim of this study was to establish whether spatial attention triggered by bimodal exogenous cues acts differently as compared to unimodal and crossmodal exogenous cues due to crossmodal integration. In order to investigate this issue, we examined cuing effects in discrimination tasks and

Integración de las normas ISO 9001 e ISO INEN 22716 en la metodología apropiada con la industria de cosméticos de Quito

OpenAIRE

Mora Quishpe, Juan Carlos

2015-01-01

The following research the integration of ISO 9001: 2008 "Quality Management Systems" INEN and ISO 22716: 2013 "Cosmetics Good Manufacturing Practices" in an appropriate methodological guide to the cosmetics industry Quito, in order for organizations that manufacture cosmetics in the city, improve the quality of their products. Initially the diagnosis of the cosmetic was held in Quito, with regard to the number of manufacturers of these industries registered by the National Health Authorit...

Nanophotonic lab-on-a-chip platforms including novel bimodal interferometers, microfluidics and grating couplers.

Science.gov (United States)

Duval, Daphné; González-Guerrero, Ana Belén; Dante, Stefania; Osmond, Johann; Monge, Rosa; Fernández, Luis J; Zinoviev, Kirill E; Domínguez, Carlos; Lechuga, Laura M

2012-05-08

One of the main limitations for achieving truly lab-on-a-chip (LOC) devices for point-of-care diagnosis is the incorporation of the "on-chip" detection. Indeed, most of the state-of-the-art LOC devices usually require complex read-out instrumentation, losing the main advantages of portability and simplicity. In this context, we present our last advances towards the achievement of a portable and label-free LOC platform with highly sensitive "on-chip" detection by using nanophotonic biosensors. Bimodal waveguide interferometers fabricated by standard silicon processes have been integrated with sub-micronic grating couplers for efficient light in-coupling, showing a phase resolution of 6.6 × 10(-4)× 2π rad and a limit of detection of 3.3 × 10(-7) refractive index unit (RIU) in bulk. A 3D network of SU-8 polymer microfluidics monolithically assembled at the wafer-level was included, ensuring perfect sealing and compact packaging. To overcome some of the drawbacks inherent to interferometric read-outs, a novel all-optical wavelength modulation system has been implemented, providing a linear response and a direct read-out of the phase variation. Sensitivity, specificity and reproducibility of the wavelength modulated BiMW sensor has been demonstrated through the label-free immunodetection of the human hormone hTSH at picomolar level using a reliable biofunctionalization process.

The role of martensitic transformation on bimodal grain structure in ultrafine grained AISI 304L stainless steel

International Nuclear Information System (INIS)

Sabooni, S.; Karimzadeh, F.; Enayati, M.H.; Ngan, A.H.W.

2015-01-01

In the present study, metastable AISI 304L austenitic stainless steel samples were subjected to different cold rolling reductions from 70% to 93%, followed by annealing at 700 °C for 300 min to form ultrafine grained (UFG) austenite with different grain structures. Transmission electron microscopy (TEM) and nanoindentation were used to characterize the martensitic transformation, in order to relate it to the bimodal distribution of the austenite grain size after subsequent annealing. The results showed that the martensite morphology changed from lath type in the 60% rolled sample to a mixture of lath and dislocation-cell types in the higher rolling reductions. Calculation of the Gibbs free energy change during the reversion treatment showed that the reversion mechanism is shear controlled at the annealing temperature and so the morphology of the reverted austenite is completely dependent on the morphology of the deformation induced martensite. It was found that the austenite had a bimodal grain size distribution in the 80% rolled and annealed state and this is related to the existence of different types of martensite. Increasing the rolling reduction to 93% followed by annealing caused changing of the grain structure to a monomodal like structure, which was mostly covered with small grains of around 300 nm. The existence of bimodal austenite grain size in the 80% rolled and annealed 304L stainless steel led to the improvement of ductility while maintaining a high tensile strength in comparison with the 93% rolled and annealed sample

Mapping ‘hydroscapes’ along the iso- to anisohydric continuum of stomatal regulation of plant water status

Science.gov (United States)

Frederick C. Meinzer; David R. Woodruff; Danielle E. Marias; Duncan D. Smith; Katherine A. McCulloh; Ava R. Howard; Alicia L. Magedman; Josep Penuelas

2016-01-01

The concept of iso- vs. anisohydry has been used to describe the stringency of stomatal regulation of plant water potential (ψ). However, metrics that accurately and consistently quantify species’ operating ranges along a continuum of iso- to anisohydry have been elusive. Additionally, most approaches to quantifying iso/anisohydry require labour-intensive measurements...

IsoCleft Finder – a web-based tool for the detection and analysis of protein binding-site geometric and chemical similarities [v2; ref status: indexed, http://f1000r.es/13y

Directory of Open Access Journals (Sweden)

Natalja Kurbatova

2013-05-01

Full Text Available IsoCleft Finder is a web-based tool for the detection of local geometric and chemical similarities between potential small-molecule binding cavities and a non-redundant dataset of ligand-bound known small-molecule binding-sites. The non-redundant dataset developed as part of this study is composed of 7339 entries representing unique Pfam/PDB-ligand (hetero group code combinations with known levels of cognate ligand similarity. The query cavity can be uploaded by the user or detected automatically by the system using existing PDB entries as well as user-provided structures in PDB format. In all cases, the user can refine the definition of the cavity interactively via a browser-based Jmol 3D molecular visualization interface. Furthermore, users can restrict the search to a subset of the dataset using a cognate-similarity threshold. Local structural similarities are detected using the IsoCleft software and ranked according to two criteria (number of atoms in common and Tanimoto score of local structural similarity and the associated Z-score and p-value measures of statistical significance. The results, including predicted ligands, target proteins, similarity scores, number of atoms in common, etc., are shown in a powerful interactive graphical interface. This interface permits the visualization of target ligands superimposed on the query cavity and additionally provides a table of pairwise ligand topological similarities. Similarities between top scoring ligands serve as an additional tool to judge the quality of the results obtained. We present several examples where IsoCleft Finder provides useful functional information. IsoCleft Finder results are complementary to existing approaches for the prediction of protein function from structure, rational drug design and x-ray crystallography. IsoCleft Finder can be found at: http://bcb.med.usherbrooke.ca/isocleftfinder.

[ISO 15189 accreditation in clinical microbiology laboratory: general concepts and the status in our laboratory].

Science.gov (United States)

Akyar, Işin

2009-10-01

One important trend in the laboratory profession and quality management is the global convergence of laboratory operations. The goal of an accredited medical laboratory is to continue "offering useful laboratory service for diagnosis and treatment of the patients and also aid to the health of the nation". An accredited clinical laboratory is managed by a quality control system, it is competent technically and the laboratory service meets the needs of all its patients and physicians by taking the responsibility of all the medical tests and therapies. For this purpose, ISO 15189 international standard has been prepared by 2003. ISO 15189 standard is originated from the arrangement of ISO 17025 and ISO 9001:2000 standards. Many countries such as England, Germany, France, Canada and Australia have preferred ISO 15189 as their own laboratory accreditation programme, meeting all the requirements of their medical laboratories. The accreditation performance of a clinical microbiology laboratory is mainly based on five essential points; preanalytical, analytical, postanalytical, quality control programmes (internal, external, interlaboratory) and audits (internal, external). In this review article, general concepts on ISO 15189 accreditation standards for the clinical microbiology laboratories have been summarized and the status of a private laboratory (Acibadem LabMed, Istanbul) in Turkey has been discussed.

EFEKTIVITAS PENGOPERASIAN INSTALASI PENGOLAH AIR LIMBAH (IPAL PERUSAHAAN PERAIH SERTIFIKASI ISO 14001 DI KAWASAN SIMONGAN KOTA SEMARANG (The Effectivity of Waste Water Treatment Plan Operated by Industrial Companies Holding ISO 14001 Certificate

Directory of Open Access Journals (Sweden)

Zaenuri Zaenuri

2012-07-01

Full Text Available ABSTRAK Penelitian ini bertujuan untuk menganalisis efektivitas pengoperasian instalasi pengolah air limbah (IPAL perusahaan peraih sel1ifikasi ISO 14001 di Kawasan Simongan Kota Semarang. Data yang diperoleh dianalisis secara deskriptif-komparatif dan inferensial dengan menggunakan uji-t. Hasil penelitian menunjukkan, pada perusahaan farmasi, rata-rata konsentrasi TSS, BOD, dan COD periode 1989-1998 (sebelum memperoleh ISO 14001 masing-masing sebesar 92,3229 mg/I, 45,5022 mg/I, dan 87,3691 mg/I, sedangkan rata-rata pH sebesar 7,2388. Parameter BOD dan COD memenuhi baku mutu, pH dalam interval baku mutu yang ditetapkan, sedangkan TSS berada di atas baku mutu. ABSTRACT This research was intended to analyze the effectivity of  waste water treatment plan operated by industrial companies holding ISO 14001 certificates in Simongan Area of SemarangCity. The data were analyzed descriptively, comparatively and inferentially using t-tests. The analyses showed that prior to obtaining ISO 14001 certificate (1989-1998, the pharmaeutical company had its average concentrations of TSS, BOD, and COD of 92.3229, 45.5022 and 87.3691 mg/l respectively, with an average pH of 7.2388. These parameters of BOD and COD had already met the prevailing standard qualities, the TSS parameter was above the standard quality, and the pH was within the prevailing standard quality interval. After obtaining the ISO 14001 certificate (2005-2008, this pharmaeutical company was able to maintain all of the key parameters to meet the prevailing stadard qualities. In case of the galvanizing company prior to obtaining ISO 14001 certificate (1989-1998, its average concentrations of TSS and CN were 256.3469 and 0.25575 mg/l respectively (above the prevailing standard qualities, those for total Cr, C+6, Cu, Zn, Ni, and Pb were 0.0510, 0.0036, 0.236060, 0.7242, 0.01790 and 0.0286 mg/l respectively (still under the prevailing standard qualities, while the an average pH was within the

Plan de implementación de la ISO/IEC 27001:2013

OpenAIRE

Gorriti Aranguren, Iñaki

2015-01-01

En el desarrollo del proyecto se analizaron las directrices establecidas en la norma ISO/IEC 27001:2013, que especifica los requisitos necesarios para establecer, implantar, mantener y mejorar un SGSI mediante un proceso de mejora continua. In the development there were analyzed the directives established in the norm ISO/IEC27001:2013, which specifies the necessary requirements to establish, to implement, to support and to improve a SGSI by means of a process of constant improvement. En...

The effect of oxide particles on the strength and ductility of bulk iron with a bimodal grain size distribution

Energy Technology Data Exchange (ETDEWEB)

Casas, C.; Tejedor, R. [Department of Materials Science and Metallurgical Engineering, ETSEIB, Universitat Politècnica de Catalunya, Av. Diagonal 647, 08028 Barcelona (Spain); Rodríguez-baracaldo, R. [Department of Mechanical Engineering, Universidad Nacional de Colombia, Bogotá. Colombia (Colombia); Benito, J.A., E-mail: Josep.a.benito@upc.edu [Department of Materials Science and Metallurgical Engineering, EUETIB, Universitat Politècnica de Catalunya, Comte d' Urgell 187, 08036 Barcelona (Spain); Fundació CTM Centre Tecnològic de Manresa, Plaça de la Ciencia, 2, 08243 Manresa (Spain); Cabrera, J.M. [Department of Materials Science and Metallurgical Engineering, ETSEIB, Universitat Politècnica de Catalunya, Av. Diagonal 647, 08028 Barcelona (Spain); Fundació CTM Centre Tecnològic de Manresa, Plaça de la Ciencia, 2, 08243 Manresa (Spain)

2015-03-11

The strength and ductility of bulk nanostructured and ultrafine-grained iron containing 0.39% oxygen by weight was determined by tensile tests. Samples were obtained by consolidation of milled iron powder at 500 °C. Heat treatments were designed to cover a wide range of grain sizes spanning from 100 to 2000 nm with different percentages of coarse and nanostructured grain areas, which was defined as a bimodal grain size distribution. Transmission electron microscopy was used to determine the diameter, volume fraction and location of oxides in the microstructure. The strength was analysed following two approaches. The first one was based on the strong effect of oxides and involved the use of a mixed particle-grain boundary strengthening model, and the second one was based on simple grain boundary strengthening. The mixed model underestimated the strength of nanostructured samples, whereas the simple grain boundary model worked better. However, for specimens with a bimodal grain size, the fitting of the mixed model was better. In this case, the more effective particle strengthening was related to the dispersion of oxides inside the large ferrite grains. In addition, the bimodal samples showed an acceptable combination of strength and ductility. Again, the ferrite grains containing oxides promoted strain hardening due to the increase in dislocation activity.

Definition of an ISO 19115 metadata profile for SeaDataNet II Cruise Summary Reports and its XML encoding

Science.gov (United States)

Boldrini, Enrico; Schaap, Dick M. A.; Nativi, Stefano

2013-04-01

SeaDataNet implements a distributed pan-European infrastructure for Ocean and Marine Data Management whose nodes are maintained by 40 national oceanographic and marine data centers from 35 countries riparian to all European seas. A unique portal makes possible distributed discovery, visualization and access of the available sea data across all the member nodes. Geographic metadata play an important role in such an infrastructure, enabling an efficient documentation and discovery of the resources of interest. In particular: - Common Data Index (CDI) metadata describe the sea datasets, including identification information (e.g. product title, interested area), evaluation information (e.g. data resolution, constraints) and distribution information (e.g. download endpoint, download protocol); - Cruise Summary Reports (CSR) metadata describe cruises and field experiments at sea, including identification information (e.g. cruise title, name of the ship), acquisition information (e.g. utilized instruments, number of samples taken) In the context of the second phase of SeaDataNet (SeaDataNet 2 EU FP7 project, grant agreement 283607, started on October 1st, 2011 for a duration of 4 years) a major target is the setting, adoption and promotion of common international standards, to the benefit of outreach and interoperability with the international initiatives and communities (e.g. OGC, INSPIRE, GEOSS, …). A standardization effort conducted by CNR with the support of MARIS, IFREMER, STFC, BODC and ENEA has led to the creation of a ISO 19115 metadata profile of CDI and its XML encoding based on ISO 19139. The CDI profile is now in its stable version and it's being implemented and adopted by the SeaDataNet community tools and software. The effort has then continued to produce an ISO based metadata model and its XML encoding also for CSR. The metadata elements included in the CSR profile belong to different models: - ISO 19115: E.g. cruise identification information, including

Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping.

Science.gov (United States)

Augustsson, Per; Karlsen, Jonas T; Su, Hao-Wei; Bruus, Henrik; Voldman, Joel

2016-05-16

Mechanical phenotyping of single cells is an emerging tool for cell classification, enabling assessment of effective parameters relating to cells' interior molecular content and structure. Here, we present iso-acoustic focusing, an equilibrium method to analyze the effective acoustic impedance of single cells in continuous flow. While flowing through a microchannel, cells migrate sideways, influenced by an acoustic field, into streams of increasing acoustic impedance, until reaching their cell-type specific point of zero acoustic contrast. We establish an experimental procedure and provide theoretical justifications and models for iso-acoustic focusing. We describe a method for providing a suitable acoustic contrast gradient in a cell-friendly medium, and use acoustic forces to maintain that gradient in the presence of destabilizing forces. Applying this method we demonstrate iso-acoustic focusing of cell lines and leukocytes, showing that acoustic properties provide phenotypic information independent of size.

Effective energy management system using ISO 9000/14000 concept industries

International Nuclear Information System (INIS)

Asfaazam Kasbani; Kamaruzzaman Sopian

2006-01-01

Energy management is a system of managing energy utilization wisely and it includes issues such as energy efficiency (conservation), use of renewable energy, use of technology and development of energy policy. Its benefits has been well known for cost reduction and increase competitiveness and also other indirect impact such as preserving the natural resources and reduction of green-house gases. Although various strategies have been formulated by the government for the industries to adopt energy management, the result seems to be minimal and stagnant in some ways due to the various barriers which exists. Industries on the other hand, have successfully welcomed two famous management system namely the Environmental Management System ISO 14000 and the Quality Management System ISO 9000 to be implemented at their premises. This paper shows how energy management system can be effectively implemented by comparing similar generic management elements of energy management to ISO 9000/14000 standards. The seven (7) elements of energy management system discussed are top management commitment, policy establishment, energy management team, energy audit, energy efficiency projects, monitoring and training

ISOS: A job evaluation system to implement comparable worth

Directory of Open Access Journals (Sweden)

Albert Corominas

2008-01-01

Full Text Available A fair pay structure is an essential element of the personnel policy of a firm. If the pay structure is perceived as arbitrary by the members of the staff, it becomes a cause of disturbance of the labor relations. Particularly, a pay structure is unfair if it discriminates against women. Job evaluation is a traditional tool used by companies to assist in the process of determining pay structures that can be also useful to detect and combat wage discrimination, since allow determining whether two jobs are of comparable worth or not. Although there are many kinds of systems, authors agree when defining point factor methods as the most appropriate and fair job evaluation systems. However, even being well defined from a technical point of view, most existing systems give discriminatory results regarding to gender. ISOS, a new job evaluation system which is described in this paper, has been designed, with the aim to define a neutral system with regard to gender, based on present jobs characteristics, existing job evaluation systems and job description questionnaires, international experts’ knowledge and a wide body of literature on gender discrimination and its relation with job evaluation. Using ISOS can contribute to detect, combat and eliminate part of the existing wage discrimination in general and, in particular, against women. ISOS includes all aspects of the work so no characteristics are omitted. The system can be applied in any company and to evaluate any job, and offers flexibility to be adapted to the specific characteristics of an organization. ISOS can also be used to detect and combat wage discrimination. Furthermore, characteristics of present jobs, such as cross-training or flexible working time, are also included so the system can be considered innovative in a very traditional field of industrial engineering.

Can the ISO-standards on quality management be useful to libraries and how?

DEFF Research Database (Denmark)

Johannsen, Carl Gustav

1994-01-01

The aim of this paper is to discuss whether the ISO 9000 concept of quality assurance is useful in a library context or not. First, the basics of the ISO 9000 series are explained. Then, the nature of the concept is discussed and the critical views raised by quality management experts are reviewed...... concluded that the whole discussion on ISO 9000 seems a little futile because the real critical success factor for libraries aiming at Total Quality does not seem to lie in the choice of a specific quality model or guru but more is a question of commitment project on quality assurance in special libraries...

Correlating the content and context of PAS 55 with the ISO 55000 series

Directory of Open Access Journals (Sweden)

Van den Honert, A. F.

2013-08-01

Full Text Available The ISO 55000 series is soon to supersede PAS 55 as the most recognised international standard for asset management. A correlation of the content and context of PAS 55 with the ISO 55000 series is required to assist organisations with the transition. After analysis of the structures, similarities, differences, and omissions of the two standards, a map was created to correlate the summarised content and context. The map established that, although both sets of standards have a similar structural framework, the ISO 55000 series is a more comprehensive and detailed standard, creating a clearer way to implement an asset management system within an organisation.

ISO Key Project: Exploring the Full Range of Quasar/Agn Properties

Science.gov (United States)

Wilkes, Belinda; Oliversen, Ronald J. (Technical Monitor)

2003-01-01

While most of the work on this program has been completed, as previously reported, the portion of the program dealing with the subtopic of ISO LWS data analysis and reduction for the LWS Extragalactic Science Team and its leader, Dr. Howard Smith, is still active. This program in fact continues to generate results, and newly available computer modeling has extended the value of the datasets. As a result the team requests a one-year no-cost extension to this program, through 31 December 2004. The essence of the proposal is to perform ISO spectroscopic studies, including data analysis and modeling, of star-formation regions using an ensemble of archival space-based data from the Infrared Space Observatory's Long Wavelength Spectrometer and Short Wavelength Spectrometer, but including as well some other spectroscopic databases. Four kinds of regions are considered in the studies: (1) disks around more evolved objects; (2) young, low or high mass pre-main sequence stars in star-formation regions; (3) star formation in external, bright IR galaxies; and (4) the galactic center. One prime focus of the program is the OH lines in the far infrared. The program has the following goals: 1) Refine the data analysis of ISO observations to obtain deeper and better SNR results on selected sources. The ISO data itself underwent 'pipeline 10' reductions in early 2001, and additional 'hands-on data reduction packages' were supplied by the ISO teams in 2001. The Fabry-Perot database is particularly sensitive to noise and slight calibration errors; 2) Model the atomic and molecular line shapes, in particular the OH lines, using revised Monte-Carlo techniques developed by the SWAS team at the Center for Astrophysics; 3) Attend scientific meetings and workshops; 4) Perform E&PO activities related to infrared astrophysics and/or spectroscopy.

EFFICIENCY OF ISO 9001 IN PORTUGAL: A QUALITATIVE STUDY FROM A HOLISTIC THEORETICAL PERSPECTIVE

Directory of Open Access Journals (Sweden)

Alcina Dias

2013-03-01

Full Text Available The purpose of this paper is to analy se the efficiency of ISO 9001 from a holistic theoretical approach where the Contingency theory, the Institutional theory and the Resources-Based View are integrated. The study was carried out in companies of different sectors of activity in Portugal, based on a qualitative methodology (interviews. The fact of the interviews having been undertaken under an ISO 9001 structure made it easier for companies to grasp the issues under investigation. An ISO 9001 characterisation was carried out on a theoretical framework approach and findings point out efficiency gains and revealed that the absence of ISO 9001 would work as a competitive disadvantage. The contribution of this research aims to reinforce the state of art as concerns the theoretical scope of analysis of these issues enriched by the case study achievement.

Rotational multispectral fluorescence lifetime imaging and intravascular ultrasound: bimodal system for intravascular applications

Science.gov (United States)

Ma, Dinglong; Bec, Julien; Yankelevich, Diego R.; Gorpas, Dimitris; Fatakdawala, Hussain; Marcu, Laura

2014-01-01

Abstract. We report the development and validation of a hybrid intravascular diagnostic system combining multispectral fluorescence lifetime imaging (FLIm) and intravascular ultrasound (IVUS) for cardiovascular imaging applications. A prototype FLIm system based on fluorescence pulse sampling technique providing information on artery biochemical composition was integrated with a commercial IVUS system providing information on artery morphology. A customized 3-Fr bimodal catheter combining a rotational side-view fiberoptic and a 40-MHz IVUS transducer was constructed for sequential helical scanning (rotation and pullback) of tubular structures. Validation of this bimodal approach was conducted in pig heart coronary arteries. Spatial resolution, fluorescence detection efficiency, pulse broadening effect, and lifetime measurement variability of the FLIm system were systematically evaluated. Current results show that this system is capable of temporarily resolving the fluorescence emission simultaneously in multiple spectral channels in a single pullback sequence. Accurate measurements of fluorescence decay characteristics from arterial segments can be obtained rapidly (e.g., 20 mm in 5 s), and accurate co-registration of fluorescence and ultrasound features can be achieved. The current finding demonstrates the compatibility of FLIm instrumentation with in vivo clinical investigations and its potential to complement conventional IVUS during catheterization procedures. PMID:24898604

Bimodality in binary Au + Au collisions from 60 to 100 MeV/u

International Nuclear Information System (INIS)

Pichon, M.; Tamain, B.; Bougault, R.

2003-03-01

The deexcitation of quasi-projectiles (QP) released in binary Au on Au collisions as been studied from 60 to 100 MeV/u. Bimodality between two different decay patterns has been observed for intermediate violence collisions. The main experimental result is that the system jumps from one mode to the other on a narrow range of energy deposit and/or impact parameter. The sorting of the events (according to the violence of the collision) has been provided by the perpendicular energy of the light charged particles emitted on the quasi-target side. Such a sorting prevents spurious autocorrelation effects between the sorting variable and the observed mechanism. The two modes of the QP decay correspond on the one side to residue or fission fragments production, and on the other side to the multifragmentation channel. A detailed study has been performed in order to try to establish the origin of the observed bimodality in disentangling dynamical or geometrical effects from bulk matter properties linked with a liquid-gas type phase transition. The whole set of data is coherent with a dominant role of the deposited excitation energy as it is expected from theoretical arguments.(lattice gas model) in the framework of a liquid-gas phase transition picture. (authors)

Inversion of multiwavelength Raman lidar data for retrieval of bimodal aerosol size distribution

Science.gov (United States)

Veselovskii, Igor; Kolgotin, Alexei; Griaznov, Vadim; Müller, Detlef; Franke, Kathleen; Whiteman, David N.

2004-02-01

We report on the feasibility of deriving microphysical parameters of bimodal particle size distributions from Mie-Raman lidar based on a triple Nd:YAG laser. Such an instrument provides backscatter coefficients at 355, 532, and 1064 nm and extinction coefficients at 355 and 532 nm. The inversion method employed is Tikhonov's inversion with regularization. Special attention has been paid to extend the particle size range for which this inversion scheme works to ~10 μm, which makes this algorithm applicable to large particles, e.g., investigations concerning the hygroscopic growth of aerosols. Simulations showed that surface area, volume concentration, and effective radius are derived to an accuracy of ~50% for a variety of bimodal particle size distributions. For particle size distributions with an effective radius of rims along which anthropogenic pollution mixes with marine aerosols. Measurement cases obtained from the Institute for Tropospheric Research six-wavelength aerosol lidar observations during the Indian Ocean Experiment were used to test the capabilities of the algorithm for experimental data sets. A benchmark test was attempted for the case representing anthropogenic aerosols between a broken cloud deck. A strong contribution of particle volume in the coarse mode of the particle size distribution was found.

Preparation of bimodal grain size 7075 aviation aluminum alloys and their corrosion properties

Directory of Open Access Journals (Sweden)

Wenming TIAN

2017-10-01

Full Text Available The bimodal grain size metals show improved strength and ductility compared to traditional metals; however, their corrosion properties are unknown. In order to evaluate the corrosion properties of these metals, the bimodal grain size 7075 aviation aluminum alloys containing different ratios of coarse (100 μm in diameter and fine (10 μm in diameter grains were prepared by spark plasma sintering (SPS. The effects of grain size as well as the mixture degree of coarse and fine grains on general corrosion were estimated by immersion tests, electrochemical measurements and complementary techniques such as scanning electron microscope (SEM and transmission electron microscope-energy disperse spectroscopy (TEM-EDS. The results show that, compared to fine grains, the coarse grains have a faster dissolution rate in acidic NaCl solution due to the bigger size, higher alloying elements content and larger area fraction of second phases in them. In coarse grains, the hydrogen ions have a faster reduction rate on cathodic second phases, therefore promoting the corrosion propagation. The mixture of coarse and fine grains also increases the electrochemical heterogeneity of alloys in micro-scale, and thus the increased mixture degree of these grains in metal matrix accelerates the corrosion rate of alloys in acidic NaCl solution.

Essence of demands of standard ISO 22000:2005 in aspect of assurances of milk health safety Istota wymagań standardu ISO 22000:2005 w aspekcie zapewnienia bezpieczeństwa zdrowotnego mleka

Directory of Open Access Journals (Sweden)

Justyna Górna

2008-09-01

Full Text Available The article presents the essence of demands of ISO 22000 as a standard which allows of control milk health safety in a more effective way. The implementation of system HACCP in the dairy companies undoubtedly make for more safety health products, however microbiological research of pasterized milk shows that it is scarce. The elementary advantage for organization which comes from food quality management system meeting demands included in standard ISO 22000 is undoubtedly assurance of legal demands concerning production of food safety and more effective control of risk of food safety. The dairy companies should aspire for implementation of more rigorous standard ISO 22000:2005.

ISO in the Construction and Manufacturing Companies: A Case Study from the Construction Industry of Hyderabad and Karachi, Pakistan

Directory of Open Access Journals (Sweden)

Nafees Ahmed Memon

2011-04-01

Full Text Available Construction industry plays very important role in development of any country. The development of construction industry depends to a larger extent on quality of construction productions and projects. Quality of construction productions and projects is linked with the implementation of QMS (Quality Management System in construction organizations. ISO certification is one of the QMS which has been adopted in manufacturing and construction industry at the global level. The construction companies of developing countries have reaped many advantages from the effective implementation of ISO standards. The rate of adoption of ISO standards has remained slow in the construction sector of some developing countries like Pakistan. This paper presents the literature review of ISO in global construction industry. It highlights the advantages, disadvantages and barriers faced by construction companies in the implementation of ISO standards. This study also investigates the level of adoption of ISO standards in construction and manufacturing companies of Pakistan through a questionnaire survey. It presents the comparison of ISO standards\\\\\\' adoption in both construction and manufacturing sectors. The paper puts forward some suggestions and recommendation for the better adoption and improvement of ISO implementation in the construction sector of Pakistan. This study emphasizes that construction companies of Pakistan should learn from the benefits reaped by the construction companies of developed countries and take appropriate measures for implementing ISO standards. It also suggests that public sector clients should make it obligatory for the contractors and consultants to have ISO certification before awarding the works in order to enhance the the adoption of ISO standards in construction sector.

Impact of 50% Synthesized Iso-Paraffins (SIP) on F-76 Fuel Coalescence

Science.gov (United States)

2013-12-16

petroleum JP-5 and Synthesized Iso-Paraffins (SIP). SIP fuels are made from direct fermentation of sugar into olefinic hydrocarbons. The olefinic...manufactured scaled down filter/coalescer and separator to simulate the performance of a full-scale filter separator system. This test is designed to predict...5 and Synthesized Iso-Paraffins (SIP). SIP fuels are made from direct fermentation of sugar into olefinic hydrocarbons. The olefinic hydrocarbons

Quality assurance standards: comparison between IAEA 50-C/SG-Q and ISO 9001:1994

International Nuclear Information System (INIS)

2000-11-01

The International Atomic Energy Agency (IAEA) and the International Organization for Standardization (ISO) agreement regarding the scope and coverage of documents published by both organizations points out that the standards of safety developed by the IAEA are recommendations for use by its Member States in the framework of national regulations for the safe utilization of nuclear energy. Such standards should be considered as nuclear safety regulatory documents. The standards developed by the ISO are complementary technical documents emphasizing industrial application and contractual aspects. Regarding the quality assurance topic, the IAEA standards 50-C/SG-Q are mostly used directly or indirectly to establish the nuclear safety requirements at the utility-regulatory interface. The industrial ISO 9001 standards have progressively been used to implement the quality assurance requirements at the interface utility-supplier. The relationship between both standards is growing in significance owing to the impact upon the owners/operators of nuclear facilities and their contractors/suppliers. The relationship between the IAEA and ISO standards is considered critical, in particular regarding suppliers with a small range of nuclear supplies. These organizations are not always willing to prepare special quality assurance programmes based on nuclear safety standards. On the other hand, these organizations may be qualified on the basis of the ISO quality assurance standards. In any case, for delivering nuclear items and services the quality assurance programme must comply with the requirements established in the nuclear safety regulatory standards. This implies that the utility-supplier will have to demonstrate that the acceptable degree of quality assurance in relation to nuclear safety is accomplished. This may be achieved by imposing additional requirements on the supplier over and above those contained within the ISO. In order to provide a description of the differences

Bahan pemutih gigi dengan sertifikat ADA/ISO (Tooth bleaching material with ADA/ISO certificate

Directory of Open Access Journals (Sweden)

Asti Meizarini

2005-06-01

Full Text Available Bleaching of teeth for cosmetic reasons is a popular aspect of cosmetic dentistry because patients realize the aesthetical benefits of these products. The dentist as a clinician's practitioner must be knowledgeable of the products and their application techniques. Bleaching materials which are safe and effective are the ADA accepted or manufactured by those which have already haved ISO certificate. Dentist must have enough knowledge about in-office bleaching prescribed for home-use bleaching including their contra indication and side effects, to advise the patients and provide effective bleaching services.

76 FR 7839 - Notice of Commission and Commission Staff Attendance at ISO/RTO Council and Regional State...

Science.gov (United States)

2011-02-11

... Staff Attendance at ISO/RTO Council and Regional State Committees Meeting The Federal Energy Regulatory... ISO/RTO Council and Regional State Committees meeting: Saturday, February 12, 2011, 1 p.m.-4 p.m... following proceeding: Docket No. AD10-5-000, RTO/ISO Performance Metrics. For more information, contact...

A primer on the Petri Net Markup Language and ISO/IEC 15909-2

DEFF Research Database (Denmark)

Hillah, L. M.; Kindler, Ekkart; Kordon, F.

2009-01-01

Standard, defines a transfer format for high-level nets. The transfer format defined in Part 2 of ISO/IEC 15909 is (or is based on) the \\emph{Petri Net Markup Language} (PNML), which was originally introduced as an interchange format for different kinds of Petri nets. In ISO/IEC 15909-2, however...

Strategy for infrared photometry of comets with ISO

Science.gov (United States)

Solc, M.; Vanysek, V.; Gruen, E.

1994-07-01

The launch of the ISO (Infrared Satellite Observatory) by the European Space Agency is scheduled for autumn 1995. Photometry and spectrophotometry observing programs of comets in the wavelength range 2.5-200 microns for the onboard spectrophotometer ISOPHOT is now under final preparation. Technical details for preparing propasals are given. Phenomena in comets to be studied are surface properties of bare cometary nuclei at large heliocentric distances, onset of coma activity, and coma dust and gas emission (in inner solar system). Dust production, dust/gas mass ratio, dust distribution in coma, and their temporal variability are important for understanding the physical processes on nuclei, and spectrophotometry in the range of 2.5-12 microns could provide us with data of the chemical composition of cometary dust. Several active comets expected for the 18-month lifetime of ISO in 1995-1997 were selected for the ISO Central Program according to their orbital and physical parameters: P/Schwassman-Wachmann 1, P/Encke, P/d'Arrest, P/Honda-Mrkos-Pajdusakova, P/Churyumov-Gerasimenko, P/Kopff, P/IRAS, P/Wirtanen, P/Wild 2, P/Grigg-Skjellerup, P/Schwassman-Wachmann 3, P/Machholz, and (2060) Chiron. Four of them match well various constraints put on the observations by the technical arrangement of the satellite and instrument. A simple four-parameter model (size, albedo, rotation, optical thickness)was developed to estimate the temperatures and thermal fluxes of both solid nuclei and dust coma.

Some considerations on the trunk Simulator ISO: experience in manufacturing, use and maintenance; Algumas consideracoes sobre o simulador de tronco da ISO: experiencia em fabricacao, uso e manutencao

Energy Technology Data Exchange (ETDEWEB)

Martins, Marcelo M.; Mauricio, Claudia L.P., E-mail: marcelo@ird.gov.br, E-mail: claudia@ird.gov.br [Instituto de Radioprotecao e Dosimetria (lRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

2013-07-01

To standardize the operational quantity H{sub p}(10), ISO defined a water slab phantom. The conversion factors from air kerma to individual dose equivalent, H{sub p}(10), for photon radiation are tabulated in ISO 4037-3, and from neutron fluence 10 H{sub p}(10) in ISO 8529-3. This paper presents some considerations concerning the manufacture, use and maintenance of seven ISO water slab phantoms. The experience of the IRD in manufacturing (in its own Mechanical Workshop) and keeping these phantoms and the main advantages and problems encountered during more than 10 years of heavy use, especially for neutron dosimetry, are fully described. An important consideration regarding the interior of the phantom relates to internal cleanliness and quality of the water used to fill it. Another is about the positioning of multiple monitors on a single simulator, including irradiation angles, and the possibility of using multi pie phantoms for isotropic irradiation fields. Finally, it is presented the problems occurred in some phantoms, such as leaks and how to fix them. The two older phantoms, employed exclusively in neutron irradiation, have visible trails of damage in polymethylmethacrylate (PMMA), converging towards its centre, along its front wall, making it more fragile. This is caused by the interaction of radiation with the PMMA. (author)

Managing your library and its quality the ISO 9001 way

CERN Document Server

Balagué, Núria

2011-01-01

This book, divided into two parts, provides an introduction to the quality management issues and gives a general overview to the use of ISO 9001 in the library environment. The second part presents the main features of ISO 9001:2008 with practical comments and examples on how to implement its clauses in libraries. Whether in the public or in the private sector, libraries can be seen as service organisations: they act in very dynamic environments where users are increasingly demanding new types of services. Thus the adoption of a quality management system helps each library in meeting the needs

Uvedba standarda ISO 9000 ter zadovoljstvo udeležencev nabavne verige = The ISO 9000 Implementation and Satisfaction of the Participants in the Supply Chain

Directory of Open Access Journals (Sweden)

Armand Faganel

2007-06-01

Full Text Available There have been written many articles about business performance, regarding the influence of ISO 9000 standards, proving the beneficial effects. However, there has been very little research made on the influence of ISO standards an the entire supply chain management. Standards have been mostly introduced into companies due to the demands of customers. But once the company has implemented the ISO philosophy, it produces a chain reaction up and down the supply chain. The customer-supplier relationship becomes more solid, trust and transparency are proliferating across the supply chain. One of the important supply chain management influences is the cooperation of companies, with the common goal of increasing the channel sales and profitability, rather than competing for a larger slice of fixed profit. We made a research with 212 certificated Slovenian companies. The standard improved the performance of supply function and the process of choosing the suppliers. If the companies can make good use of the standard, there are many opportunities in the field of approach improvement to the suppliers. Companies with longer use of the standard have achieved greater impact with the quality of supplies, suppliers responsiveness, punctuality and affidability.

Experimental investigation on SI engine using gasoline and a hybrid iso-butanol/gasoline fuel

International Nuclear Information System (INIS)

Elfasakhany, Ashraf

2015-01-01

Highlights: • iso-Butanol–gasoline blends (iB) using up to 10 vol.% butanol were examined in SIE. • iB extensively decrease the greenhouse effect of SI engine. • iB without engine tuning led to a drop in engine performance at all speeds. • iB provide higher performance and lower CO and CO 2 emissions than n-butanol blends. • iB grant lower CO and UHC than gasoline at <2900 r/min, but overturn at >2900 r/min. - Abstract: Experimental investigation on pollutant emissions and performance of SI engine fueled with gasoline and iso-butanol–gasoline blends is carried out. Engine was operated at speed range of 2600–3400 r/min for each blend (3, 7 and 10 vol.% iso-butanol) and neat gasoline. Results declare that the CO and UHC emissions of neat gasoline are higher than those of the blended fuels for speeds less than or equal to 2900 r/min; however, for speeds higher than 2900 r/min, we have an opposite impact where the blended fuels produce higher level of CO and UHC emissions than the gasoline fuel. The CO 2 emission at using iso-butanol–gasoline blends is always lower than the neat gasoline at all speeds by up to 43%. The engine performance results demonstrate that using iso-butanol–gasoline blends in SI engine without any engine tuning lead to a drop in engine performance within all speed range. Without modifying the engine system, overall fuel combustion of iso-butanol–gasoline blends was quasi-complete. However, when engine system is optimized for blended fuels, iso-butanol has significant oxygen content and that can lead to a leaner combustion, which improves the completeness of combustion and therefore high performance and less emissions would be obtained. Finally, the performance and emissions of iso-butanol–gasoline blends are compared with those of n-butanol–gasoline blends at similar blended rates and engine working conditions. Such comparison is directed to evaluate the combustion dissimilarity of the two butanol isomers and also to

A formal analysis of ISO/IEEE P11073-20601 standard of medical device communication

NARCIS (Netherlands)

Goga, Nicolae; Costache, Stefania; Moldoveanu, Florica

2009-01-01

This article presents the formal work done for the ISO/IEEE P11073-20601 Draft Standard for Health informatics - Personal health device communication - Application profile Optimized exchange protocol. ISO/IEEE 11073 family defines standards for device communication between agents (e.g. blood

75 FR 3225 - Notice of Commission Staff Attendance at Organization of MISO States and Midwest ISO Meetings

Science.gov (United States)

2010-01-20

... Organization of MISO States and Midwest ISO Meetings January 12, 2010. The Federal Energy Regulatory Commission...: Midwest ISO Headquarters, 720 City Center Drive, Carmel, IN 46032. Except as otherwise noted above, the... Operator, Inc. Docket No. ER08-15, Midwest ISO Transmission Owners Docket No. ER08-55, Midwest Independent...

Analysis of ISO/IEC 17025 for establishment of KOLAS (Korea Laboratory Accreditation Scheme) quality assurance system

International Nuclear Information System (INIS)

Nam, Ji Hee

2000-12-01

Besides one existent accredited lab, radioactive material chemical analysis lab, five test laboratories and two calibration labs are under plan to acquire the accreditation from KOLAS. But the current Quality Manual was developed according to ISO Guide 25 that was superceded by ISO/IEC 17025. Since it is tailored to the radioactive material chemical analysis lab, a number of requirements of the Manual are not applicable to the labs other than radioactive material chemical analysis lab. Through the analysis of ISO/IEC 17025, a model of quality system was established which is not only consistent with ISO/IEC 17025 but reflective of the KAERI's situation

Characterization of Slosh Damping for Ortho-Grid and Iso-Grid Internal Tank Structures

Science.gov (United States)

Westra, Douglas G.; Sansone, Marco D.; Eberhart, Chad J.; West, Jeffrey S.

2016-01-01

Grid stiffened tank structures such as Ortho-Grid and Iso-Grid are widely used in cryogenic tanks for providing stiffening to the tank while reducing mass, compared to tank walls of constant cross-section. If the structure is internal to the tank, it will positively affect the fluid dynamic behavior of the liquid propellant, in regard to fluid slosh damping. As NASA and commercial companies endeavor to explore the solar system, vehicles will by necessity become more mass efficient, and design margin will be reduced where possible. Therefore, if the damping characteristics of the Ortho-Grid and Iso-Grid structure is understood, their positive damping effect can be taken into account in the systems design process. Historically, damping by internal structures has been characterized by rules of thumb and for Ortho-Grid, empirical design tools intended for slosh baffles of much larger cross-section have been used. There is little or no information available to characterize the slosh behavior of Iso-Grid internal structure. Therefore, to take advantage of these structures for their positive damping effects, there is much need for obtaining additional data and tools to characterize them. Recently, the NASA Marshall Space Flight Center conducted both sub-scale testing and computational fluid dynamics (CFD) simulations of slosh damping for Ortho-Grid and Iso-Grid tanks for cylindrical tanks containing water. Enhanced grid meshing techniques were applied to the geometrically detailed and complex Ortho-Grid and Iso-Grid structures. The Loci-STREAM CFD program with the Volume of Fluid Method module for tracking and locating the water-air fluid interface was used to conduct the simulations. The CFD simulations were validated with the test data and new empirical models for predicting damping and frequency of Ortho-Grid and Iso-Grid structures were generated.

Management system quality of service radio physics and RR. ISO 9001; Sistema de gestion de la calidad de un servicio de radiofisica y P. R. segun ISO 9001

Energy Technology Data Exchange (ETDEWEB)

Gil Agudo, A.; Torres Donaire, J.; Jimenez, J. C.; Carrascosa Fernandez, C.; Arjona Gutierrez, J.

2011-07-01

One of the tool increasingly deployed for the optimization of the procedures is the process management system according to a Quality Management. Likewise, for specific areas, such as central services within large institutions such as the General Hospitals of the systems of quality management is the most widely used ISO 9001. We describe in this paper our experience in implementing the system ISO 9001 in our Department of Radio physics and Radiation Protection (SRFPR).

Exploring the Impact of ISO 9001, ISO 14001 and OHSAS 18001 Certification on Financial Performance: The Case of Companies listed on the Bucharest Stock Exchange

Directory of Open Access Journals (Sweden)

Mihaela Ionașcu

2017-02-01

Full Text Available The purpose of this paper is to investigate the impact of ISO 9001, ISO 14001 and OHSAS 18001 certification on the financial performance of Romanian companies listed on the Bucharest Stock Exchange (BSE. Based on audited financial statements of a population of 67 non-financial companies listed during 2013-2015 and using regression models, this paper shows, for the first time in Romania, that companies listed on BSE, implementing complex management systems (quality – environmental and/or occupational health and safety perform better, and that their performance is directly linked to the complexity of the management systems implemented.

The costs and benefits of getting the ISO 9000 certification in the manufacturing sector in Saudi Arabia.

Science.gov (United States)

Mezher, T; Ramadan, H

1998-01-01

Many Saudi companies, in their journey to improve quality, efficiency and competitiveness, are pursuing and obtaining the ISO 9000 certificate. Many studies have evaluated how to implement ISO 9000 in different sectors, but none have analyzed the effectiveness of ISO 9000 certification (costs and benefits) on improving the overall quality and on meeting expectations. This study addressed these issues by investigating manufacturing organizations in Saudi Arabia that have the ISO 9000 certification. A survey questionnaire was distributed to firms throughout the kingdom. Thirty-two firms participated in the study. Results indicate that increased consistency of operations, improved service, and product quality are among the top motivators for pursuing the ISO certificate. The benefits most often experienced were improved awareness of procedural problems, better management control, keeping existing customers, increased customer satisfaction, and improved customer service. Difficulties experienced during the certification process involved time and cost, but these were not considered to be major problems. A high volume of paperwork was the main problem experienced following initial certification. Respondents in general said that the ISO 9000 certification met their expectations and that their level of satisfaction regarding the impact of ISO 9000 was high. Most recommended that other organizations pursue the certificate.

ISO 9000 and the total quality management models

OpenAIRE

Pacios Lozano, Ana Reyes

1997-01-01

Establishes the most outstanding differences between the ISO 9000 norms and total quality management as forms or manners of managing quality used in some information services. Compares two models of total quality: European Foundation far Quality Management and Malcolm Baldrige Awards.

Elaboration of austenitic stainless steel samples with bimodal grain size distributions and investigation of their mechanical behavior

Science.gov (United States)

Flipon, B.; de la Cruz, L. Garcia; Hug, E.; Keller, C.; Barbe, F.

2017-10-01

Samples of 316L austenitic stainless steel with bimodal grain size distributions are elaborated using two distinct routes. The first one is based on powder metallurgy using spark plasma sintering of two powders with different particle sizes. The second route applies the reverse-annealing method: it consists in inducing martensitic phase transformation by plastic strain and further annealing in order to obtain two austenitic grain populations with different sizes. Microstructural analy ses reveal that both methods are suitable to generate significative grain size contrast and to control this contrast according to the elaboration conditions. Mechanical properties under tension are then characterized for different grain size distributions. Crystal plasticity finite element modelling is further applied in a configuration of bimodal distribution to analyse the role played by coarse grains within a matrix of fine grains, considering not only their volume fraction but also their spatial arrangement.

Systems Engineering and Management Applications of ISO 9001:2015 for Government

Science.gov (United States)

Shepherd, Christena C.

2016-01-01

The manufacturing segment of the business world is busy assessing the impact of ISO 9001:2015, and updating their management systems to meet the required compliance date. What does the new revision mean for government agencies that deliver large engineering projects rather than mass production? In fact, the standard, especially the new revision, can be used quite readily for government agencies, or applied to specific projects, once it is understood in terms of the similarities with systems engineering and project management. From there it can be extrapolated to "mission realization" systems, and a Quality Management System (QMS) is a logical result that can bring order to processes and systems that likely already exist in some fashion. ISO 9001:2015 is less product-oriented than previous versions. It can be more broadly applied to public organizations as well as private; and to services (missions) as well as products. The emphasis on risk management in the revised standard provides the needed balance for weighing decisions with respect to cost, schedule, technical, safety, and regulatory compliance; so if this is not part of agency governance already, this is a good place to start, especially for large engineering projects. The Systems Engineering standard used for this analysis is from NASA's NPR 7123.1 NASA Systems Engineering Processes and Requirements; however, those who are more familiar with ISO/IEC 26702 Systems Engineering-application and management of the systems engineering process, or SAE/EIA 632 Processes for Engineering a System will also recognize the similarities. In reality, the QMS outlined by ISO 9001 reinforces the systems engineering processes, and serves to ensure that they are adequately implemented, although most of the ISO 9001 literature emphasizes the production and process aspects of the standard. Rather than beginning with ISO 9001and getting lost in the vocabulary, it is useful to begin with the systems engineering lifecycle

Knowledge Engineering Aspects of Affective Bi-Modal Educational Applications

Science.gov (United States)

Alepis, Efthymios; Virvou, Maria; Kabassi, Katerina

This paper analyses the knowledge and software engineering aspects of educational applications that provide affective bi-modal human-computer interaction. For this purpose, a system that provides affective interaction based on evidence from two different modes has been developed. More specifically, the system's inferences about students' emotions are based on user input evidence from the keyboard and the microphone. Evidence from these two modes is combined by a user modelling component that incorporates user stereotypes as well as a multi criteria decision making theory. The mechanism that integrates the inferences from the two modes has been based on the results of two empirical studies that were conducted in the context of knowledge engineering of the system. The evaluation of the developed system showed significant improvements in the recognition of the emotional states of users.

The impact of ISO/TS 16949 on automotive industries and created organizational capabilities from its implementation

Directory of Open Access Journals (Sweden)

Bakhtiar Ostadi

2010-12-01

Full Text Available ISO/TS 16949 is an ISO Technical Specification. ISO/TS 16949 achieves the objectives which are continually to improve the production of automobile parts and related services, and to strengthen the international competition for the automotive industry and its suppliers. By applying this quality system standard, automotive manufacturers could offer superior products and good services to customers. The more the companies know about the benefits if quality management systems such as ISO/TS 16949, better they can seek interest and determine indices of these systems. So, this standard has been implemented in companies considering a number of benefits. In this paper, we carry out an empirical study in order to verify the importance these benefits and ranking them based on the value of importance. Finally, the study tends to provide a reference guide considering benefits assessment and created organizational capabilities from this standard for the automotive industry in pursuing ISO/TS 16949 and procuring maximum benefit from the results.

A comprehensive iso-octane combustion model with improved thermochemistry and chemical kinetics

KAUST Repository

Atef, Nour

2017-02-05

Iso-Octane (2,2,4-trimethylpentane) is a primary reference fuel and an important component of gasoline fuels. Moreover, it is a key component used in surrogates to study the ignition and burning characteristics of gasoline fuels. This paper presents an updated chemical kinetic model for iso-octane combustion. Specifically, the thermodynamic data and reaction kinetics of iso-octane have been re-assessed based on new thermodynamic group values and recently evaluated rate coefficients from the literature. The adopted rate coefficients were either experimentally measured or determined by analogy to theoretically calculated values. Furthermore, new alternative isomerization pathways for peroxy-alkyl hydroperoxide (ȮOQOOH) radicals were added to the reaction mechanism. The updated kinetic model was compared against new ignition delay data measured in rapid compression machines (RCM) and a high-pressure shock tube. These experiments were conducted at pressures of 20 and 40 atm, at equivalence ratios of 0.4 and 1.0, and at temperatures in the range of 632–1060 K. The updated model was further compared against shock tube ignition delay times, jet-stirred reactor oxidation speciation data, premixed laminar flame speeds, counterflow diffusion flame ignition, and shock tube pyrolysis speciation data available in the literature. Finally, the updated model was used to investigate the importance of alternative isomerization pathways in the low temperature oxidation of highly branched alkanes. When compared to available models in the literature, the present model represents the current state-of-the-art in fundamental thermochemistry and reaction kinetics of iso-octane; and thus provides the best prediction of wide ranging experimental data and fundamental insights into iso-octane combustion chemistry.

Neuroprotective effects of α-iso-cubebene against glutamate-induced damage in the HT22 hippocampal neuronal cell line.

Science.gov (United States)

Park, Sun Young; Jung, Won Jung; Kang, Jum Soon; Kim, Cheol-Min; Park, Geuntae; Choi, Young-Whan

2015-02-01

Since oxidative stress is critically involved in excitotoxic damage, we sought to determine whether the activation of the transcription factors, cAMP-responsive element binding protein (CREB) and nuclear factor (erythroid-derived 2)-like 2 (Nrf2, also known as NFE2L2), by α-iso-cubebene is involved in its protective effects against glutamate-induced neuronal cell death. Pre-treatment with α-iso-cubebene significantly attenuated glutamate-induced cytotoxicity in mouse hippocampus-derived neuronal cells. α-iso-cubebene also reduced the glutamate-induced generation of reactive oxygen species and calcium influx, thus preventing apoptotic cell death. α-iso-cubebene inhibited glutamate-induced mitochondrial membrane depolarization and, consequently, inhibited the release of the apoptosis-inducing factor from the mitochondria. Immunoblot anlaysis revealed that the phosphorylation of extracellular signal-regulated kinase (ERK) by glutamate was reduced in the presence of α-iso-cubebene. α-iso-cubebene activated protein kinase A (PKA), CREB and Nrf2, which mediate the expression of the antioxidant enzymes, heme oxygenase-1 (HO-1) and NAD(P)H dehydrogenase [quinone] 1 (NQO1), involved in neuroprotection. In addition, α-iso-cubebene induced the expression of antioxidant responsive element and CRE transcriptional activity, thus conferring neuroprotection against glutamate-induced oxidative injury. α-iso-cubebene also induced the expression of Nrf2-dependent genes encoding HO-1 and NQO1. Furthermore, the knockdown of CREB and Nrf2 by small interfering RNA attenuated the neuroprotective effects of α-iso-cubebene. Taken together, our results indicate that α-iso-cubebene protects HT22 cells from glutamate-induced oxidative damage through the activation of Nrf2/HO-1/NQO-1, as well as through the PKA and CREB signaling pathways.

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