WorldWideScience

Sample records for big blue bump

  1. Seeing the Unseen: MIR Spectroscopic Constraints on Quasar Big Blue Bumps

    Science.gov (United States)

    Gallagher, Sarah; Hines, Dean; Leighly, Karen; Ogle, Patrick; Richards, Gordon

    2008-03-01

    The IRS on Spitzer offers an exciting opportunity for detailed, mid-infrared spectroscopy of z~2 quasars for the first time. This epoch, sampling the peak of the quasar luminosity evolution, is particularly important for understanding the nature of quasar activity in the most massive galaxies. We aim to use this powerful tool to constrain the shape and power of the far-ultraviolet through soft-X-ray ionizing continuum of luminous quasars. Though these so-called `big blue bumps' dominate the power of quasar spectral energy distributions, they are largely unobservable as a result of hydrogen opacity in the Universe. However, we can determine the properties of the big blue bump by studying emission lines from ions in the coronal line region that emit in the mid-infrared and are created by those same energetic and elusive photons. We propose deep, high quality IRS observations of 5 luminous quasars with a range of HeII emission properties to investigate the mid-infrared spectral region in depth and constrain the shape of the ionizing continuum in each quasar. In addition, these high S/N spectra will provide templates for interpreting lower resolution, lower S/N IRS spectra.

  2. Nonlinear calculations for bump Cepheids

    International Nuclear Information System (INIS)

    Hodson, S.W.; Cox, A.N.

    1979-01-01

    Hydrodynamic calculations to find strictly periodic solutions for the fundamental mode pulsations of 7 M/sub sun/ models were made using the von Sengbusch--Stellingwerf relaxation method. The models have a helium enrichment in the surface convection zones to Y = 0.78, which from the linear theory period ratio π 2 /π 0 and the Simon and Schmidt resonance hypothesis, should give the observed Hertzsprung progression of light and velocity curve bump phase with period. These surface helium enhanced models show the proper nonlinear bump phase behavior without resort to any mass loss before or during the blue loop phases of yellow giant evolution. At 6000 K and the evolution theory luminosity of 4744 L/sub sun/ for 7 M/sub sun/, that is, at a fundamental mode period of 8.5 day, the velocity curve bump is well after the maximum expansion velocity. At 5400 K and at the same luminosity (period of 12.5 days), there is a bump on the velocity curve well before maximum expansion velocity time. The latter case seems to exhibit the Christy echos but not the former. The echo interpretation may not be appropriate for these masses which are larger than the anomalous masses used by Christy, Stobie, and Adams. Resonance of the fundamental and second overtone modes should not necessarily show echos of surface disturbances from the center. The conclusion is that helium enrichment in the surface convection zones can adequately explain observations of bump Cepheids at evolution theory masses. 12 references

  3. Comparison of Off-Line IR Bump and Action-Angle Kick Minimization

    CERN Document Server

    Luo, Yun; Ptitsyn, Vadim; Trbojevic, Dejan; Wei, Jie

    2005-01-01

    The interaction region bump (IR bump) nonlinear correction method has been used for the sextupole and octupole field error on-line corrections in the Relativistic Heavy Ion Collider (RHIC). Some differences were found for the sextupole and octupole corrector strengths between the on-line IR bump correction and the predictions from the action-angle kick minimization. In this report we compare the corrector strengths from these two methods based on the RHIC Blue ring lattice with the IR nonlinear modeling. The comparison confirms the differences between resulting corrector strengths. And the reason for the differences is found and discussed. It is followed by a further discussion of the operational IR bump applications to the octupole, and skew sextupole and skew quadrupole field error corrections.

  4. New magic angle bumps and magic translation bumps

    International Nuclear Information System (INIS)

    Seeman, J.

    1983-01-01

    SLC beams of opposite charge can be transversely deflected in the same direction by RF fields in the accelerating cavities caused by girder tilts, coupler-asymmetries, or manufacturing errors. A symmetric deflection can be corrected by a magic angle bump if the deflection is located adjacent to one of the linac quadrupoles. However, if the deflection is located between quadrupoles, two magic angle bumps or a magic angle bump and a magic translation bump are needed for the correction. Several examples of translation bumps are included. A new magic angle bump is also presented which is longitudinally compressed and has significantly reduced particle excursions. Finally, if new correctors are added midway along the girders so that the number of correctors are doubled, then the longitudinal extent and the maximum particle excursion of these new magic bumps can be further reduced

  5. 78 FR 6316 - Big Blue Wind Farm, LLC, et al.; Notice of Effectiveness of Exempt Wholesale Generator Status

    Science.gov (United States)

    2013-01-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EG13-1-000, et al.] Big Blue Wind Farm, LLC, et al.; Notice of Effectiveness of Exempt Wholesale Generator Status Docket Nos. Big Blue Wind Farm, LLC EG13-1-000 Calpine Bosque Energy Center, LLC EG13-2-000 Homer City Generation, L.P...

  6. ICHEP 2016: to b(ump) or not to b(ump)

    CERN Multimedia

    2016-01-01

    This week I’m in Chicago for the 38th International Conference on High Energy Physics, ICHEP 2016, hosted this year by the US particle physics community. While it became clear at the conference that the famous 750 GeV bump has flatlined, there’s been a wealth of physics from CERN and around the world.   Everyone in their heart felt that the bump would turn out to be no more than a statistical fluctuation, while secretly hoping that it would be something new. Even the designer of the ICHEP 2016 logo cleverly hid a bump with a subtle question mark in the Chicago skyline – appropriately enough in Anish Kapoor’s mysterious ‘Cloud Gate’ sculpture. That question mark has now been resolved. Kapoor’s sculpture returns to being just that, and the search for new physics goes on albeit further constrained as theorists revealed in the 400+ papers in the wake of the bump discussion. The highlight from CERN was undoubtedly the spectacular pe...

  7. The Online Big Blue Test for Promoting Exercise: Health, Self-Efficacy, and Social Support.

    Science.gov (United States)

    Gómez-Zúñiga, Beni; Pousada, Modesta; Hernandez, Manny M; Colberg, Sheri; Gabarrón, Elia; Armayones, Manuel

    2015-10-01

    Recent articles have documented the influence of self-efficacy and social support on exercising. Simultaneously, insulin use is also related to the perception of self-efficacy and social support in patients with diabetes. We combine these two ideas through the Big Blue Test experience in a social networking site and propose to analyze whether a change in blood sugar levels after completion of the Big Blue Test and insulin use are related to the perception of self-efficacy and social support in patients with diabetes. To undergo the Big Blue Test, 3,926 participants voluntarily joined the Diabetes Hands Foundation. Responses were analyzed using descriptive analysis. The participants who reduced their blood glucose after exercise the least were those with lower self-efficacy and also with lower perceived social support. There seems to have been no relationship between changes in blood sugar level and the explicit intention of doing exercise in the future. Insulin-dependent participants demonstrated a lower perception of self-efficacy and social support than non-insulin-dependent participants. Change in blood glucose level or being insulin-dependent or not do not explain completely a health behavior such as exercise. Hence, self-efficacy and social support have an impact on behavioral change such as exercise to become a habit in people with diabetes, and this experience through a social networking site is an important tool for this behavioral change. For exercise to become a habit in people with diabetes, it is necessary to consider not only the crucial physiological variables, but also those psychological variables that clearly have an impact on behavioral change.

  8. Vehicle speed control using road bumps

    Directory of Open Access Journals (Sweden)

    T. A. O. Salau

    2004-06-01

    Full Text Available Road bumps play a crucial role in enforcing speed limits, thereby preventing overspeeding of vehicles. It significantly contributes to the overall road safety objective through the prevention of accidents that lead to deaths of pedestrians and damage of vehicles. Despite the importance of road bumps, very little research has been done to investigate into their design. While documentation exists on quantitative descriptions of road bumps, they offer little guidance to decision making. This work presents a unique approach to solving road bumps design problems. The results of our study reveal three important road bumps variables that influence the control of vehicle speeds. The key variables are bump height, bump width, and effective distance between two consecutive road bumps. Since vehicle speed control is the ultimate aim of this study the relationship between vehicle speed and other variables earlier mentioned is established. Vehicle speed is defined as the product of frequency at which a vehicle is moving over road bumps and the sum of effective distance between two consecutive road bumps. In the determination of bump height we assume a conical shaped curve for analysis as a matter of research strategy. Based on this, two stages of motion were analysed. The first concerns the motion over the bump itself while the second relates to the motion between two consecutive road bumps. Fourier series was then used to formulate a holistic equation that combines these two stages. We used trigonometric functions to model the behaviour of the first stage while with the second stage giving a functional value of zero since no changes in height are observed. We carried out vibration analysis to determine the effect of road bumps on a vehicular system. Arising from this a model component is referred to as an isolation factor. This offers guidance to the safe frequency at which vehicles could travel over road bumps. The work appears to contribute to knowledge

  9. The reminiscence bump reconsidered: Children's prospective life stories show a bump in young adulthood

    DEFF Research Database (Denmark)

    Bohn, Annette; Berntsen, Dorthe

    2011-01-01

    showed a clear bump in young adulthood. In Study 2, children were prompted by word cues to write down events from their future lives. The events generated consisted mostly of non-life-script events, and those events did not show a bump in young adulthood. Our findings challenge prevailing explanations...

  10. Bump Bonding Using Metal-Coated Carbon Nanotubes

    Science.gov (United States)

    Lamb, James L.; Dickie, Matthew R.; Kowalczyk, Robert S.; Liao, Anna; Bronikowski, Michael J.

    2012-01-01

    Bump bonding hybridization techniques use arrays of indium bumps to electrically and mechanically join two chips together. Surface-tension issues limit bump sizes to roughly as wide as they are high. Pitches are limited to 50 microns with bumps only 8-14 microns high on each wafer. A new process uses oriented carbon nanotubes (CNTs) with a metal (indium) in a wicking process using capillary actions to increase the aspect ratio and pitch density of the connections for bump bonding hybridizations. It merges the properties of the CNTs and the metal bumps, providing enhanced material performance parameters. By merging the bumps with narrow and long CNTs oriented in the vertical direction, higher aspect ratios can be obtained if the metal can be made to wick. Possible aspect ratios increase from 1:1 to 20:1 for most applications, and to 100:1 for some applications. Possible pitch density increases of a factor of 10 are possible. Standard capillary theory would not normally allow indium or most other metals to be drawn into the oriented CNTs, because they are non-wetting. However, capillary action can be induced through the ability to fabricate oriented CNT bundles to desired spacings, and the use of deposition techniques and temperature to control the size and mobility of the liquid metal streams and associated reservoirs. This hybridization of two technologies (indium bumps and CNTs) may also provide for some additional benefits such as improved thermal management and possible current density increases.

  11. The reminiscence bump reconsidered: children's prospective life stories show a bump in young adulthood.

    Science.gov (United States)

    Bohn, Annette; Berntsen, Dorthe

    2011-02-01

    The reminiscence bump-the reporting of more memories from young adulthood than from other stages of life-is considered a hallmark of autobiographical memory research. The most prevalent explanations for this effect assume that events in young adulthood are favored because of the way they are encoded and maintained in long-term memory. Here we show that a similar increase of events in early adulthood is found when children narrate their personal futures. In Study 1, children wrote their future life stories. The events in these life stories were mostly life-script events, and their distribution showed a clear bump in young adulthood. In Study 2, children were prompted by word cues to write down events from their future lives. The events generated consisted mostly of non-life-script events, and those events did not show a bump in young adulthood. Our findings challenge prevailing explanations of the reminiscence bump and suggest that the cultural life script forms an overarching organizational principle for autobiographical memories and future representations across the life span.

  12. Recent advances in understanding the reminiscence bump

    DEFF Research Database (Denmark)

    Koppel, Jonathan; Rubin, David C.

    2016-01-01

    The reminiscence bump is the increased proportion of autobiographical memories from youth and early adulthood observed in adults over 40. It is one of the most robust findings in autobiographical-memory research. Although described as a single period from which there are more memories, a recent...... meta-analysis that reported the beginning and ending ages of the bump from individual studies found that different classes of cues produce distinct bumps that vary in size and temporal location. The bump obtained in response to cue words is both smaller and located earlier in the life span than...

  13. HANFORD WASTE TANK BUMP ACCIDENT & CONSEQUENCE ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    MEACHAM, J.E.

    2005-02-22

    Postulated physical scenarios leading to tank bumps were examined. A combination of a substantial supernatant layer depth, supernatant temperatures close to saturation, and high sludge temperatures are required for a tank bump to occur. Scenarios postulated at various times for sludge layers lacking substantial supernatant, such as superheat within the layer and fumarole formation leading to a bump were ruled out.

  14. Tank Bump Accident Potential and Consequences During Waste Retrieval

    International Nuclear Information System (INIS)

    BRATZEL, D.R.

    2000-01-01

    This report provides an evaluation of Hanford tank bump accident potential and consequences during waste retrieval operations. The purpose of this report is to consider the best available new information to support recommendations for safety controls. A new tank bump accident analysis for safe storage (Epstein et al. 2000) is extended for this purpose. A tank bump is a postulated event in which gases, consisting mostly of water vapor, are suddenly emitted from the waste and cause tank headspace pressurization. Tank bump scenarios, physical models, and frequency and consequence methods are fully described in Epstein et al. (2000). The analysis scope is waste retrieval from double-shell tanks (DSTs) including operation of equipment such as mixer pumps and air lift circulators. The analysis considers physical mechanisms for tank bump to formulate criteria for bump potential during retrieval, application of the criteria to the DSTs, evaluation of bump frequency, and consequence analysis of a bump. The result of the consequence analysis is the mass of waste released from tanks; radiological dose is calculated using standard methods (Cowley et al. 2000)

  15. Single bumps in a 2-population homogenized neuronal network model

    Science.gov (United States)

    Kolodina, Karina; Oleynik, Anna; Wyller, John

    2018-05-01

    We investigate existence and stability of single bumps in a homogenized 2-population neural field model, when the firing rate functions are given by the Heaviside function. The model is derived by means of the two-scale convergence technique of Nguetseng in the case of periodic microvariation in the connectivity functions. The connectivity functions are periodically modulated in both the synaptic footprint and in the spatial scale. The bump solutions are constructed by using a pinning function technique for the case where the solutions are independent of the local variable. In the weakly modulated case the generic picture consists of two bumps (one narrow and one broad bump) for each admissible set of threshold values for firing. In addition, a new threshold value regime for existence of bumps is detected. Beyond the weakly modulated regime the number of bumps depends sensitively on the degree of heterogeneity. For the latter case we present a configuration consisting of three coexisting bumps. The linear stability of the bumps is studied by means of the spectral properties of a Fredholm integral operator, block diagonalization of this operator and the Fourier decomposition method. In the weakly modulated regime, one of the bumps is unstable for all relative inhibition times, while the other one is stable for small and moderate values of this parameter. The latter bump becomes unstable as the relative inhibition time exceeds a certain threshold. In the case of the three coexisting bumps detected in the regime of finite degree of heterogeneity, we have at least one stable bump (and maximum two stable bumps) for small and moderate values of the relative inhibition time.

  16. Eyelid bump

    Science.gov (United States)

    ... It appears as a red, swollen bump that looks like a pimple. It is often tender to the touch. Causes A stye is caused by a blockage of one of the oil glands in the eyelids. This allows bacteria to grow inside the blocked gland. Styes are ...

  17. The reminiscence bump in autobiographical memory and for public events

    DEFF Research Database (Denmark)

    Koppel, Jonathan; Berntsen, Dorthe

    2016-01-01

    of public events. We did so between-subjects, through two cueing methods administered within-subjects, the cue word method and the important memories method. For word-cued memories, we found a similar bump from ages 5 to 19 for both types of memories. However, the bump was more pronounced...... for autobiographical memories. For most important memories, we found a bump from ages 20 to 29 in autobiographical memory, but little discernible age pattern for public events. Rather, specific public events (e.g., the Fall of the Berlin Wall) dominated recall, producing a chronological distribution characterised......The reminiscence bump has been found for both autobiographical memories and memories of public events. However, there have been few comparisons of the bump across each type of event. In the current study, therefore, we compared the bump for autobiographical memories versus the bump for memories...

  18. A flip chip process based on electroplated solder bumps

    Science.gov (United States)

    Salonen, J.; Salmi, J.

    1994-01-01

    Compared to wire bonding and TAB, flip chip technology using solder joints offers the highest pin count and packaging density and superior electrical performance. The chips are mounted upside down on the substrate, which can be made of silicon, ceramic, glass or - in some cases - even PCB. The extra processing steps required for chips are the deposition of a suitable thin film metal layer(s) on the standard Al pad and the formation of bumps. Also, the development of new fine line substrate technologies is required to utilize the full potential of the technology. In our bumping process, bump deposition is done by electroplating, which was chosen for its simplicity and economy. Sputter deposited molybdenum and copper are used as thin film layers between the aluminum pads and the solder bumps. A reason for this choice is that the metals can be selectively etched after bumping using the bumps as a mask, thus circumventing the need for a separate mask for etching the thin film metals. The bumps are electroplated from a binary Pb-Sn bath using a thick liquid photoresist. An extensively modified commercial flip chip bonder is used for alignment and bonding. Heat assisted tack bonding is used to attach the chips to the substrate, and final reflow joining is done without flux in a vacuum furnace.

  19. Light and velocity curve bumps for BW Vulpeculae

    International Nuclear Information System (INIS)

    Pesnell, W.D.; Cox, A.N.

    1980-01-01

    Bumps in the light and radial velocity curves of the Beta Cephei star BW Vulpeculae were modeled. Two mechanisms, a resonance phenomena and non-linear pulsations, were investigated. The resonance condition was clearly not fulfilled, the calculated period ratio being approximately 0.60, where a value of 0.50 L +- 0.03 is required for resonance. In the non-linear calculation, the bump appears, with the correct phase, but was found at an amplitude that is too large. Further, the light curve does not show any bump-like feature. The cause of the bump is the large spurious boost given the star's velocity field by the solution methods. The calculated periods of the stellar models are shorter than those of previous calculations, enhancing the possibility that these stars pulsate in a radial fundamental mode

  20. Structural integrity of power generating speed bumps made of concrete foam composite

    Science.gov (United States)

    Syam, B.; Muttaqin, M.; Hastrino, D.; Sebayang, A.; Basuki, W. S.; Sabri, M.; Abda, S.

    2018-02-01

    In this paper concrete foam composite speed bumps were designed to generate electrical power by utilizing the movements of commuting vehicles on highways, streets, parking gates, and drive-thru station of fast food restaurants. The speed bumps were subjected to loadings generated by vehicles pass over the power generating mechanical system. In this paper, we mainly focus our discussion on the structural integrity of the speed bumps and discuss the electrical power generating speed bumps in another paper. One aspect of structural integrity is its ability to support designed loads without breaking and includes the study of past structural failures in order to prevent failures in future designs. The concrete foam composites were used for the speed bumps; the reinforcement materials are selected from empty fruit bunch of oil palm. In this study, the speed bump materials and structure were subjected to various tests to obtain its physical and mechanical properties. To analyze the structure stability of the speed bumps some models were produced and tested in our speed bump test station. We also conduct a FEM-based computer simulation to analyze stress responses of the speed bump structures. It was found that speed bump type 1 significantly reduced the radial voltage. In addition, the speed bump is equipped with a steel casing is also suitable for use as a component component in generating electrical energy.

  1. Decomposing the sales promotion bump with store data

    NARCIS (Netherlands)

    van Heerde, H.J.; Leeflang, P.S.H.; Wittink, D.R.

    2004-01-01

    Sales promotions generate substantial short-term sales increases. To determine whether the sales promotion bump is truly beneficial from a managerial perspective, we propose a system of store-level regression models that decomposes the sales promotion bump into three parts: cross-brand effects

  2. Thermohydrodynamic analysis of airfoil bearing based on bump foil structure

    Directory of Open Access Journals (Sweden)

    S.Y. Maraiy

    2016-09-01

    Full Text Available The load carrying capacity of the gas foil bearing depends on the material properties and the configuration of the underlying bump strip’s structure. This paper presents three different cases for selecting the dimensions of the foil bearing to guarantee the highest possible load carrying capacity. It focuses on three main parameters that affect the compliance number; these parameters are the length of bump in θ direction, the pitch of bump foil, and the thickness of bump foil. It also studies the effect of changing these parameters on load carrying capacity according to both isothermal and thermohydrodynamic approaches.

  3. Shrinking of bumps by drawing scintillating fibres through a hot conical tool

    CERN Document Server

    Rodrigues Cavalcante, Ana Barbara; Gavardi, Laura; Joram, Christian; Kristic, Robert; Pierschel, Gerhard; Schneider, Thomas

    2016-01-01

    The LHCb SciFi tracker will be based on scintillating fibres with a nominal diameter of 250 $\\mu$m. A small length fraction of these fibres shows millimetre-scale fluctuations of the diameter, also known as bumps and necks. In particular, bumps exceeding a diameter of about 350 $\\mu$m are problematic as they can distort the winding pattern of the fibre mats over more extended regions. We present a method to reduce the diameter of large bumps to a diameter of 350 $\\mu$m by locally heating and pulling the fibre through a conical tool. The method has been proven to work for bumps up to 450 – 500 $\\mu$m diameter. Larger bumps need to be treated manually by a cut-and-glue technique which relies on UV-curing instant glue. The bump shrinking and cut-and-glue processes were integrated in a fibre diameter scanner at CERN. The central scanning and bump shrinking of all fibres is expected to minimise bump related issues at the four mat winding centres of the SciFi project.

  4. A Metal Bump Bonding Method Using Ag Nanoparticles as Intermediate Layer

    Science.gov (United States)

    Fu, Weixin; Nimura, Masatsugu; Kasahara, Takashi; Mimatsu, Hayata; Okada, Akiko; Shoji, Shuichi; Ishizuka, Shugo; Mizuno, Jun

    2015-11-01

    The future development of low-temperature and low-pressure bonding technology is necessary for fine-pitch bump application. We propose a bump structure using Ag nanoparticles as an intermediate layer coated on a fine-pitch Cu pillar bump. The intermediate layer is prepared using an efficient and cost-saving squeegee-coating method followed by a 100°C baking process. This bump structure can be easily flattened before the bonding process, and the low-temperature sinterability of the nanoparticles is retained. The bonding experiment was successfully performed at 250°C and 39.8 MPa and the bonding strength was comparable to that achieved via other bonding technology utilizing metal particles or porous material as bump materials.

  5. Bump masses for BL Her stars

    International Nuclear Information System (INIS)

    Davis, C.G.

    1982-01-01

    The masses of classical Cepheids can be determined by using the phase of the Hertzsprung bump on the light or velocity curve, Cox-Stewart opacities, and nonlinear pulsation theory. The fact that these bump masses are some 60% lower than the evolutionary masses raises some questions about this approach. In support of our method, we calculate the light curve for BL Her, a population II Cepheid, with an observed bump on the declining portion of its light curve. The nonlinear hydrodynamic model we use (Davis and Davison - 1978) resolves the light curve by dynamic zoning and allows us the opportunity to make a direct comparison of the calculated light curve to the observations, using a prescribed mass, luminosity and effective temperature. The parameters for BL Her are from a linear model (Hodson, Cox, and King - 1982) that has nearly the correct period (1./sup d/2) and the correct period ratio from resonance theory (π 2 /π 0 = 0.53) for a bump to appear on the declining portion of the light curve as observed. These parameters are: M = 0.55 M, L = 95.0 L, and T/sub eff/ = 6500 K. This mass is near the evolutionary mass as described by Schwartzschild and Haerm (1970). The model results agree well with the observations and the color-T/sub eff/ relation has the same slope as that observed for RR Lyrae stars by the Oke, Giver and Searle (1965) relationship

  6. The Effects of Campus Bump on Drivers’ Fixation Dispersion and Speed Reduction

    Directory of Open Access Journals (Sweden)

    Qian Xu

    2015-01-01

    Full Text Available To evaluate the effects of campus speed bumps on drivers’ speed and fixation distribution, a quasinaturalistic driving test was conducted on a Chinese campus. Seven randomly selected drivers, wearing the Dikablis eye tracking devices, were required to drive an OPEL SUV passing the speed bumps. The area close to the bump was divided into ten subsegments (15 m for each one. The degree of fixation dispersion within each subsegment was defined as the distance from each subcenter to the whole fixation center. All traffic data were recorded using mounted camera, and the trajectories were extracted in Matlab. The speed and trajectory data was divided into two groups: the before group for bump-free case and the after group for a 5 cm bump case. The observational before-after analysis shows statistical significance between the two cases. The individual vehicular speed analysis reveals that bump reduces nearly 60% of vehicles’ speeds to a certain extent within the distance from 30 m upstream to 15 m downstream. The drivers’ fixation points begin to disperse 30–45 m before they see the bump, and it falls back to normal level 15–30 m downstream of the bump. These findings will help engineers install speed bumps at the most appropriate locations.

  7. The Physics of Bump Drafting in Car Racing

    Science.gov (United States)

    Fiolhais, Miguel C. N.; Amor dos Santos, Susana

    2014-01-01

    The technique of bump drafting, also known as two-car drafting in motorsports, is analysed in the framework of Newtonian mechanics and simple aerodynamic drag forces. As an apparent unnatural effect that often pleases the enthusiasts of car racing, bump drafting provides a unique pedagogical opportunity for students to gain insights into the…

  8. Visual Analysis of Speeding Bumps Using Floating Car Dataset

    DEFF Research Database (Denmark)

    Kveladze, Irma; Agerholm, Niels

    2018-01-01

    measures, and also their influence on the driving behaviour of vehicles from a temporal perspective. To fill this gap and understand these aspects, in this research we propose visual analytics techniques. To explore the influence of the bumps on speed change behavior of vehicles, several use case studies...... in three different cities were selected with close cooperation of a traffic domain expert. The aim was first to study influence of the bumps on vehicle volume and speeding from a time perspective. And then, establish any connection between speed bump intervals and vehicle speeding in the selected use cases...

  9. Low-cost bump-bonding processes for high energy physics pixel detectors

    CERN Document Server

    AUTHOR|(CDS)2069357; Blank, Thomas; Colombo, Fabio; Dierlamm, Alexander Hermann; Husemann, Ulrich; Kudella, Simon; Weber, M

    2016-01-01

    In the next generation of collider experiments detectors will be challenged by unprecedented particle fluxes. Thus large detector arrays of highly pixelated detectors with minimal dead area will be required at reasonable costs. Bump-bonding of pixel detectors has been shown to be a major cost-driver. KIT is one of five production centers of the CMS barrel pixel detector for the Phase I Upgrade. In this contribution the SnPb bump-bonding process and the production yield is reported. In parallel to the production of the new CMS pixel detector, several alternatives to the expensive photolithography electroplating/electroless metal deposition technologies are developing. Recent progress and challenges faced in the development of bump-bonding technology based on gold-stud bonding by thin (15 μm) gold wire is presented. This technique allows producing metal bumps with diameters down to 30 μm without using photolithography processes, which are typically required to provide suitable under bump metallization. The sh...

  10. Two-Step Plasma Process for Cleaning Indium Bonding Bumps

    Science.gov (United States)

    Greer, Harold F.; Vasquez, Richard P.; Jones, Todd J.; Hoenk, Michael E.; Dickie, Matthew R.; Nikzad, Shouleh

    2009-01-01

    A two-step plasma process has been developed as a means of removing surface oxide layers from indium bumps used in flip-chip hybridization (bump bonding) of integrated circuits. The two-step plasma process makes it possible to remove surface indium oxide, without incurring the adverse effects of the acid etching process.

  11. Development of an Indium Bump Bond Process for Silicon Pixel Detectors at PSI

    CERN Document Server

    Brönnimann, C; Gobrecht, J; Heising, S; Horisberger, M; Horisberger, R P; Kästli, H C; Lehmann, J; Rohe, T; Streuli, S; Broennimann, Ch.

    2006-01-01

    The hybrid pixel detectors used in the high energy physics experiments currently under construction use a three dimensional connection technique, the so-called bump bonding. As the pitch below 100um, required in these applications, cannot be fullfilled with standard industrial processes (e.g. the IBM C4 process), an in-house bump bond process using reflown indium bumps was developed at PSI as part of the R&D for the CMS-pixel detector. The bump deposition on the sensor is performed in two subsequent lift-off steps. As the first photolithographic step a thin under bump metalization (UBM) is sputtered onto bump pads. It is wettable by indium and defines the diameter of the bump. The indium is evaporated via a second photolithographic step with larger openings and is reflown afterwards. The height of the balls is defined by the volume of the indium. On the readout chip only one photolithographic step is carried out to deposit the UBM and a thin indium layer for better adhesion. After mating both parts a seco...

  12. A Journey of Change with a Big Blue Whale: A Theatre-in-Education (TIE) Programme on Disability and Dilemmas in the Inclusive Classroom in Korea

    Science.gov (United States)

    Kim, Byoung-Joo

    2009-01-01

    The article chronicles and discusses "A Big Blue Whale's Dream," one of the first major theatre-in-education (TIE) projects commissioned by local and governmental cultural foundations in South Korea. Designed specifically for the non-disabled fifth and sixth graders of Inclusive Classes to enhance their awareness and perception towards…

  13. Cross-Validation of Survival Bump Hunting by Recursive Peeling Methods.

    Science.gov (United States)

    Dazard, Jean-Eudes; Choe, Michael; LeBlanc, Michael; Rao, J Sunil

    2014-08-01

    We introduce a survival/risk bump hunting framework to build a bump hunting model with a possibly censored time-to-event type of response and to validate model estimates. First, we describe the use of adequate survival peeling criteria to build a survival/risk bump hunting model based on recursive peeling methods. Our method called "Patient Recursive Survival Peeling" is a rule-induction method that makes use of specific peeling criteria such as hazard ratio or log-rank statistics. Second, to validate our model estimates and improve survival prediction accuracy, we describe a resampling-based validation technique specifically designed for the joint task of decision rule making by recursive peeling (i.e. decision-box) and survival estimation. This alternative technique, called "combined" cross-validation is done by combining test samples over the cross-validation loops, a design allowing for bump hunting by recursive peeling in a survival setting. We provide empirical results showing the importance of cross-validation and replication.

  14. ARE ULTRA-LONG GAMMA-RAY BURSTS CAUSED BY BLUE SUPERGIANT COLLAPSARS, NEWBORN MAGNETARS, OR WHITE DWARF TIDAL DISRUPTION EVENTS?

    Energy Technology Data Exchange (ETDEWEB)

    Ioka, Kunihito [Center for Gravitational Physics, Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan); Hotokezaka, Kenta; Piran, Tsvi, E-mail: kunihito.ioka@yukawa.kyoto-u.ac.jp [Racah Institute of Physics, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel)

    2016-12-10

    Ultra-long gamma-ray bursts (ulGRBs) are a new population of GRBs with extreme durations of ∼10{sup 4} s. Leading candidates for their origin are blue supergiant collapsars, magnetars, and white dwarf tidal disruption events (WD-TDEs) caused by massive black holes (BHs). Recent observations of supernova-like (SN-like) bumps associated with ulGRBs challenged both the WD-TDE and the blue supergiant models because of the detection of SNe and the absence of hydrogen lines, respectively. We propose that WD-TDEs can accommodate the observed SN-like bumps if the fallback WD matter releases energy into the unbound WD ejecta. The observed ejecta energy, luminosity, and velocity are explained by the gravitational energy, Eddington luminosity, and escape velocity of the formed accretion disk, respectively. We also show that the observed X-rays can ionize the ejecta, eliminating lines. The SN-like light curves (SN 2011kl) for the ulGRB 111209A are consistent with all three models, although a magnetar model is unnatural because the spin-down time required to power the SN-like bump is a hundred times longer than the GRB. Our results imply that TDEs are a possible energy source for SN-like events in general and for ulGRBs in particular.

  15. Stability of bumps in piecewise smooth neural fields with nonlinear adaptation

    KAUST Repository

    Kilpatrick, Zachary P.

    2010-06-01

    We study the linear stability of stationary bumps in piecewise smooth neural fields with local negative feedback in the form of synaptic depression or spike frequency adaptation. The continuum dynamics is described in terms of a nonlocal integrodifferential equation, in which the integral kernel represents the spatial distribution of synaptic weights between populations of neurons whose mean firing rate is taken to be a Heaviside function of local activity. Discontinuities in the adaptation variable associated with a bump solution means that bump stability cannot be analyzed by constructing the Evans function for a network with a sigmoidal gain function and then taking the high-gain limit. In the case of synaptic depression, we show that linear stability can be formulated in terms of solutions to a system of pseudo-linear equations. We thus establish that sufficiently strong synaptic depression can destabilize a bump that is stable in the absence of depression. These instabilities are dominated by shift perturbations that evolve into traveling pulses. In the case of spike frequency adaptation, we show that for a wide class of perturbations the activity and adaptation variables decouple in the linear regime, thus allowing us to explicitly determine stability in terms of the spectrum of a smooth linear operator. We find that bumps are always unstable with respect to this class of perturbations, and destabilization of a bump can result in either a traveling pulse or a spatially localized breather. © 2010 Elsevier B.V. All rights reserved.

  16. Two-Dimensional Bumps in Piecewise Smooth Neural Fields with Synaptic Depression

    KAUST Repository

    Bressloff, Paul C.; Kilpatrick, Zachary P.

    2011-01-01

    instability leads to the formation of a traveling spot. The local stability of a bump is determined by solutions to a system of pseudolinear equations that take into account the sign of perturbations around the circular bump boundary. © 2011 Society

  17. Pain over speed bumps in diagnosis of acute appendicitis: diagnostic accuracy study.

    Science.gov (United States)

    Ashdown, Helen F; D'Souza, Nigel; Karim, Diallah; Stevens, Richard J; Huang, Andrew; Harnden, Anthony

    2012-12-14

    To assess the diagnostic accuracy of pain on travelling over speed bumps for the diagnosis of acute appendicitis. Prospective questionnaire based diagnostic accuracy study. Secondary care surgical assessment unit at a district general hospital in the UK. 101 patients aged 17-76 years referred to the on-call surgical team for assessment of possible appendicitis. Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios for pain over speed bumps in diagnosing appendicitis, with histological diagnosis of appendicitis as the reference standard. The analysis included 64 participants who had travelled over speed bumps on their journey to hospital. Of these, 34 had a confirmed histological diagnosis of appendicitis, 33 of whom reported increased pain over speed bumps. The sensitivity was 97% (95% confidence interval 85% to 100%), and the specificity was 30% (15% to 49%). The positive predictive value was 61% (47% to 74%), and the negative predictive value was 90% (56% to 100%). The likelihood ratios were 1.4 (1.1 to 1.8) for a positive test result and 0.1 (0.0 to 0.7) for a negative result. Speed bumps had a better sensitivity and negative likelihood ratio than did other clinical features assessed, including migration of pain and rebound tenderness. Presence of pain while travelling over speed bumps was associated with an increased likelihood of acute appendicitis. As a diagnostic variable, it compared favourably with other features commonly used in clinical assessment. Asking about speed bumps may contribute to clinical assessment and could be useful in telephone assessment of patients.

  18. Stability of bumps in piecewise smooth neural fields with nonlinear adaptation

    KAUST Repository

    Kilpatrick, Zachary P.; Bressloff, Paul C.

    2010-01-01

    associated with a bump solution means that bump stability cannot be analyzed by constructing the Evans function for a network with a sigmoidal gain function and then taking the high-gain limit. In the case of synaptic depression, we show that linear stability

  19. Electrical characteristics for Sn-Ag-Cu solder bump with Ti/Ni/Cu under-bump metallization after temperature cycling tests

    Science.gov (United States)

    Shih, T. I.; Lin, Y. C.; Duh, J. G.; Hsu, Tom

    2006-10-01

    Lead-free solder bumps have been widely used in current flip-chip technology (FCT) due to environmental issues. Solder joints after temperature cycling tests were employed to investigate the interfacial reaction between the Ti/Ni/Cu under-bump metallization and Sn-Ag-Cu solders. The interfacial morphology and quantitative analysis of the intermetallic compounds (IMCs) were obtained by electron probe microanalysis (EPMA) and field emission electron probe microanalysis (FE-EPMA). Various types of IMCs such as (Cu1-x,Agx)6Sn5, (Cu1-y,Agy)3Sn, and (Ag1-z,Cuz)3Sn were observed. In addition to conventional I-V measurements by a special sample preparation technique, a scanning electron microscope (SEM) internal probing system was introduced to evaluate the electrical characteristics in the IMCs after various test conditions. The electrical data would be correlated to microstructural evolution due to the interfacial reaction between the solder and under-bump metallurgy (UBM). This study demonstrated the successful employment of an internal nanoprobing approach, which would help further understanding of the electrical behavior within an IMC layer in the solder/UBM assembly.

  20. On the persistence of unstable bump-on-tail electron velocity distributions in the earth's foreshock

    International Nuclear Information System (INIS)

    Klimas, A.J.; Fitzenreiter, R.J.

    1988-01-01

    Further evidence for the persistence of bump-on-tail unstable reduced velocity distribution in the Earth's electron foreshock is presented. This persistence contradicts our understanding of quasi-linear saturation of the bump-on-tail instability; the distributions should be stabilized through velocity space diffusion too quickly to allow an observation of their unstable form. A modified theory for the saturation of the bump-on-tail instability in the Earth's foreshock is proposed and examined using numerical simulation and quasi-linear theoretical techniques. It is argued the mechanism due to Filbert and Kellogg and to Cairns which is responsible for the creation of the bump-on-tail velocity distribution in the foreshock is still operative during the evolution of the bump-on-tail instability. The saturated state of the plasma must represent a balance between this creation mechanism and velocity space diffusion; the saturated state is not determined by velocity space diffusion alone. Thus the velocity distribution of the saturated stat may still appear bump-on-tail unstable to standard linear analysis which does not take the creation mechanism into account. The bump-on-tail velocity distributions in the foreshock would then represent the state of the plasma after saturation of the bump-on-tail instability, not before

  1. Stress Distribution in a Coal Seam before and after Bump Initiation

    Directory of Open Access Journals (Sweden)

    J. Vacek

    2001-01-01

    Full Text Available This paper deals with to the behaviour of open rock that occurs, for example, during longwall mining in coal mines, in deep tunnel, or shaft excavation.Longwall instability leads to extrusion of rock mass into an open space. This effect is mostly referred to as a bump, or a rock burst. For bumps to occur, the rock has to possess certain particular rock burst properties leading to accumulation of energy and the potential to release this energy. Such materials may be brittle, or the bumps may arise at the interfacial zones of two parts of the rock, that have principally different material properties.The solution is based on experimental and mathematical modelling. These two methods have to allow the problem to be studied on the basis of three presumptions: – the solution must be time dependent – the solution must allow the creation of crack in the rock mass – the solution must allow an extrusion of rock into an open space (bump effect

  2. Two-Dimensional Bumps in Piecewise Smooth Neural Fields with Synaptic Depression

    KAUST Repository

    Bressloff, Paul C.

    2011-01-01

    We analyze radially symmetric bumps in a two-dimensional piecewise-smooth neural field model with synaptic depression. The continuum dynamics is described in terms of a nonlocal integrodifferential equation, in which the integral kernel represents the spatial distribution of synaptic weights between populations of neurons whose mean firing rate is taken to be a Heaviside function of local activity. Synaptic depression dynamically reduces the strength of synaptic weights in response to increases in activity. We show that in the case of a Mexican hat weight distribution, sufficiently strong synaptic depression can destabilize a stationary bump solution that would be stable in the absence of depression. Numerically it is found that the resulting instability leads to the formation of a traveling spot. The local stability of a bump is determined by solutions to a system of pseudolinear equations that take into account the sign of perturbations around the circular bump boundary. © 2011 Society for Industrial and Applied Mathematics.

  3. Injection Bump Synchronization Study for the CERN PS

    CERN Document Server

    Serluca, Maurizio; Gilardoni, Simone; CERN. Geneva. ATS Department

    2016-01-01

    In the framework of the LHC Injector Upgrade (LIU) project the CERN PS injection kinetic energy will be upgraded from 1.4 to 2 GeV. The present injection bump is made by four bumpers in Straight Section (SS) 40, 42, 43, 44 and it will be converted in a five bumpers system to allow additional flexibility in the bump shape with a reduction of the proton losses during the bump closure. The injection section SS42 has being redesigned to accommodate a new eddy current septum which will host a new bumper magnet in the same vacuum vessel due to reduced longitudinal space availability. The synchronization and amplitude variation of the power converter of the in-vacuum bumper 42 with respect to the remaining outside vacuum bumpers 40, 41, 43, 44 can lead to orbit distortion and consequent losses during injection. In this note we present the experimental results from Machine Development (MD) studies along with simulations for the present system at 1.4 GeV to quantify the acceptable orbit distortion and the performance ...

  4. Fluxless flip-chip bonding using a lead-free solder bumping technique

    Science.gov (United States)

    Hansen, K.; Kousar, S.; Pitzl, D.; Arab, S.

    2017-09-01

    With the LHC exceeding the nominal instantaneous luminosity, the current barrel pixel detector (BPIX) of the CMS experiment at CERN will reach its performance limits and undergo significant radiation damage. In order to improve detector performance in high luminosity conditions, the entire BPIX is replaced with an upgraded version containing an additional detection layer. Half of the modules comprising this additional layer are produced at DESY using fluxless and lead-free bumping and bonding techniques. Sequential solder-jetting technique is utilized to wet 40-μm SAC305 solder spheres on the silicon-sensor pads with electroless Ni, Pd and immersion Au (ENEPIG) under-bump metallization (UBM). The bumped sensors are flip-chip assembled with readout chips (ROCs) and then reflowed using a flux-less bonding facility. The challenges for jetting low solder volume have been analyzed and will be presented in this paper. An average speed of 3.4 balls per second is obtained to jet about 67 thousand solder balls on a single chip. On average, 7 modules have been produced per week. The bump-bond quality is evaluated in terms of electrical and mechanical properties. The peak-bump resistance is about 17.5 mΩ. The cross-section study revealed different types of intermetallic compounds (IMC) as a result of interfacial reactions between UBM and solder material. The effect of crystalline phases on the mechanical properties of the joint is discussed. The mean shear strength per bump after the final module reflow is about 16 cN. The results and sources of yield loss of module production are reported. The achieved yield is 95%.

  5. From Big Data to Big Displays High-Performance Visualization at Blue Brain

    KAUST Repository

    Eilemann, Stefan; Abdellah, Marwan; Antille, Nicolas; Bilgili, Ahmet; Chevtchenko, Grigory; Dumusc, Raphael; Favreau, Cyrille; Hernando, Juan; Nachbaur, Daniel; Podhajski, Pawel; Villafranca, Jafet; Schü rmann, Felix

    2017-01-01

    Blue Brain has pushed high-performance visualization (HPV) to complement its HPC strategy since its inception in 2007. In 2011, this strategy has been accelerated to develop innovative visualization solutions through increased funding and strategic

  6. Running bumps from stealth bosons

    Science.gov (United States)

    Aguilar-Saavedra, J. A.

    2018-03-01

    For the `stealth bosons' S, light boosted particles with a decay S → A A → q \\bar{q} q \\bar{q} into four quarks and reconstructed as a single fat jet, the groomed jet mass has a strong correlation with groomed jet substructure variables. Consequently, the jet mass distribution is strongly affected by the jet substructure selection cuts when applied on the groomed jet. We illustrate this fact by recasting a CMS search for low-mass dijet resonances and show a few representative examples. The mass distributions exhibit narrow and wide bumps at several locations in the 100-300 GeV range, between the masses of the daughter particles A and the parent particle S, depending on the jet substructure selection. This striking observation introduces several caveats when interpreting and comparing experimental results, for the case of non-standard signatures. The possibility that a single boosted particle decaying hadronically produces multiple bumps, at quite different jet masses, and depending on the event selection, brings the anomaly chasing game to the next level.

  7. Running bumps from stealth bosons

    International Nuclear Information System (INIS)

    Aguilar-Saavedra, J.A.

    2018-01-01

    For the 'stealth bosons' S, light boosted particles with a decay S → AA → q anti qq anti q into four quarks and reconstructed as a single fat jet, the groomed jet mass has a strong correlation with groomed jet substructure variables. Consequently, the jet mass distribution is strongly affected by the jet substructure selection cuts when applied on the groomed jet. We illustrate this fact by recasting a CMS search for low-mass dijet resonances and show a few representative examples. The mass distributions exhibit narrow and wide bumps at several locations in the 100-300 GeV range, between the masses of the daughter particles A and the parent particle S, depending on the jet substructure selection. This striking observation introduces several caveats when interpreting and comparing experimental results, for the case of non-standard signatures. The possibility that a single boosted particle decaying hadronically produces multiple bumps, at quite different jet masses, and depending on the event selection, brings the anomaly chasing game to the next level. (orig.)

  8. On the persistence of unstable bump-on-tail electron velocity distributions in the earth's foreshock

    Science.gov (United States)

    Klimas, Alexander J.; Fitzenreiter, Richard J.

    1988-01-01

    This paper presents further evidence for the persistence of bump-on-tail unstable reduced velocity distributions in the earth's electron foreshock, which contradicts the understanding of quasi-linear saturation of the bump-on-tail instability. A modified theory for the saturation of the bump-on-tail instability in the earth's foreshock is proposed to explain the mechanism of this persistence, and the predictions are compared to the results of a numerical simulation of the electron plasma in the foreshock. The results support the thesis that quasi-linear saturation of the bump-on-tail instability is modified in the foreshock, due to the driven nature of the region, so that at saturation the stabilized velocity distribution still appears bump-on-tail unstable to linear plasma analysis.

  9. Effect of wettability and topological features of Namib beetle inspired bumps on dropwise condensation

    Science.gov (United States)

    Ahmad, Shakeel; Tang, Hui; Yao, Haimin

    2017-11-01

    The Stenocara beetle lives in arid desert environment where the only available source of water is fog droplets. The beetle contains many hydrophobic/hydrophilic bumps on its back. Water collection occurs on the hydrophilic patches. Once the droplet reaches the critical volume, it sheds down due to gravity. Although a number of studies on condensation and water collection on beetle inspired structures have been reported in literature, most of them were on micro/nano scale textures. However, in nature the beetle bumps are in millimeter scale. At this scale the role of topological features and gravity becomes crucial for early droplet shedding. Therefore, in this work we numerically investigated the effects of bump shape, wettability contrast, surface slope and hydrophilic patch to total area ratio on droplet shedding volume and time. A three-dimensional lattice Boltzmann method (LBM) based numerical framework was used for the simulations. Compared with bumps of other shapes such a cube or a circular cylinder, faster droplet shedding was obtained over a hemispherical bump. Furthermore, it was found that larger hydrophilic patch to total area ratio for the hemispherical bump significantly increased the droplet shedding time.

  10. Investigation of Sn-Pb solder bumps of prototype photo detectors for the LHCb experiment

    CERN Document Server

    Delsante, M L; Arnau-Izquierdo, G

    2004-01-01

    The Large Hadron Collider (LHC) is now under construction at the European Organization for Nuclear Research (CERN). LHCb is one of the dedicated LHC experiments, allowing high energy proton-proton collisions to be exploited. This paper presents the results of the metallurgic studies carried out on Sn-Pb solder bumps of prototype vacuum photo detectors under development for LHCb, and in particular for the ring imaging Cherenkov-hybrid photo diode (RICH-HPD) project. These detectors encapsulate, in a vacuum tube, an assembly made of two silicon chips bonded together by a matrix of solder bumps. Each bump lies on a suitable system of under-bump metallic layers ensuring mechanical and electrical transition between the chip pad and the solder alloy. During manufacturing of the detector, bump-bonded (BB) assemblies are exposed to severe heat cycles up to 400 degree C inducing, in the present fabrication process, a clear degradation of electrical connectivity. Several investigations such as microstructural observati...

  11. The peaks of life: The differential temporal locations of the reminiscence bump across disparate cueing methods

    DEFF Research Database (Denmark)

    Koppel, Jonathan Mark; Berntsen, Dorthe

    2015-01-01

    The reminiscence bump has generally been assessed through either (1) the cue word method, or (2) several related methods which we refer to under the umbrella of the important memories method. Here we provide a review of the literature demonstrating that the temporal location of the bump varies...... systematically according to cueing method, with the mean range of the bump located from 8.7 to 22.5 years of age for word-cued memories, versus 15.1 to 27.9 for important memories. This finding has hitherto been under-acknowledged, as existing theoretical accounts of the bump generally hold its location...... to be stable across cueing methods. We therefore re-evaluate existing theoretical accounts of the bump in light of these varying locations, addressing each account’s consistency with (1) the respective bumps found through each method taken individually, and (2) the sensitivity of the bump’s location to cueing...

  12. Generating ekpyrotic curvature perturbations before the big bang

    International Nuclear Information System (INIS)

    Lehners, Jean-Luc; Turok, Neil; McFadden, Paul; Steinhardt, Paul J.

    2007-01-01

    We analyze a general mechanism for producing a nearly scale-invariant spectrum of cosmological curvature perturbations during a contracting phase preceding a big bang, which can be entirely described using 4D effective field theory. The mechanism, based on first producing entropic perturbations and then converting them to curvature perturbations, can be naturally incorporated in cyclic and ekpyrotic models in which the big bang is modeled as a brane collision, as well as other types of cosmological models with a pre-big bang phase. We show that the correct perturbation amplitude can be obtained and that the spectral tilt n s tends to range from slightly blue to red, with 0.97 s <1.02 for the simplest models, a range compatible with current observations but shifted by a few percent towards the blue compared to the prediction of the simplest, large-field inflationary models

  13. New Pulsed Orbit Bump Magnets for the Fermilab Booster Synchrotron

    CERN Document Server

    Lackey, James; John, Carson; Kashikhin, Vladimir; Makarov, Alexander; Prebys, Eric

    2005-01-01

    The beam from the Fermilab Linac is injected onto a bump in the closed orbit of the Booster Synchrotron where a carbon foil strips the electrons from the Linac’s negative ion hydrogen beam. Although the Booster itself runs at 15Hz, heat dissipation in the orbit bump magnets has been one limitation to the fraction of the cycles that can be used for beam. New, 0.28T pulsed window frame dipole magnets have been constructed that will fit into the same space as the old ones, run at the full repetition rate of the Booster, and provide a larger bump to allow a cleaner injection orbit. The new magnets use a high saturation flux density Ni-Zn ferrite in the yoke rather than laminated steel. The presented magnetic design includes two and three dimensional magnetic field calculations with eddy currents and ferrite nonlinear effects.

  14. Effectiveness of Emittance Bumps in the NLC and US Cold LC Main Linear Accelerators (LCC-0138)

    International Nuclear Information System (INIS)

    Tenenbaum, P

    2004-01-01

    We report on a series of studies on the effectiveness of closed orbit bumps in the linacs of the NLC and the USColdLC. In the first study, emittance dilutions of a pure-wakefield or pure-dispersion character are introduced in each linac, and a set of emittance bumps is tested to determine the most effective bump location in the linac, and the net effectiveness. In the second study, a more realistic set of dilutions are introduced and the wakefield bumps used in the first study are applied

  15. Bump formation in a binary attractor neural network

    International Nuclear Information System (INIS)

    Koroutchev, Kostadin; Korutcheva, Elka

    2006-01-01

    The conditions for the formation of local bumps in the activity of binary attractor neural networks with spatially dependent connectivity are investigated. We show that these formations are observed when asymmetry between the activity during the retrieval and learning is imposed. An analytical approximation for the order parameters is derived. The corresponding phase diagram shows a relatively large and stable region where this effect is observed, although critical storage and information capacities drastically decrease inside that region. We demonstrate that the stability of the network, when starting from the bump formation, is larger than the stability when starting even from the whole pattern. Finally, we show a very good agreement between the analytical results and the simulations performed for different topologies of the network

  16. Cascading reminiscence bumps in popular music.

    Science.gov (United States)

    Krumhansl, Carol Lynne; Zupnick, Justin Adam

    2013-10-01

    Autobiographical memories are disproportionately recalled for events in late adolescence and early adulthood, a phenomenon called the reminiscence bump. Previous studies on music have found autobiographical memories and life-long preferences for music from this period. In the present study, we probed young adults' personal memories associated with top hits over 5-and-a-half decades, as well as the context of their memories and their recognition of, preference for, quality judgments of, and emotional reactions to that music. All these measures showed the typical increase for music released during the two decades of their lives. Unexpectedly, we found that the same measures peaked for the music of participants' parents' generation. This finding points to the impact of music in childhood and suggests that these results reflect the prevalence of music in the home environment. An earlier peak occurred for 1960s music, which may be explained by its quality or by its transmission through two generations. We refer to this pattern of musical cultural transmission over generations as cascading reminiscence bumps.

  17. Reminiscence bump in memory for public events

    NARCIS (Netherlands)

    Janssen, S.M.J.; Murre, J.M.J.; Meeter, M.

    2008-01-01

    People tend to recall more personal events from adolescence and early adulthood than from other lifetime periods. Most evidence suggests that differential encoding causes this reminiscence bump. However, the question why personal events are encoded better in those periods is still unanswered. To

  18. CO2 laser-induced bump formation and growth on polystyrene for multi-depth soft lithography molds

    International Nuclear Information System (INIS)

    Li, Huawei; Fan, Yiqiang; Conchouso, David; Foulds, Ian G

    2012-01-01

    This paper reports the process of creating bumps on the surface of polystyrene (PS) induced by a CO 2 laser at low powers. The paper also outlines the procedure for growing bumps induced by multiple laser scans on the aforementioned bumps. These bumps result from the net volume gain of the laser heat-affected zone on the PS rather than from a deposition process, and the expansion of the heat-affected zone on PS was verified by measuring the hardness change using nanoindentation. The bumps have a much smoother surface than microchannels fabricated with laser cutting; depending on the laser power, they have heights ranging from hundreds of nanometers to 42 µm. The laser scanning speed and scan times along with this technique offer a fast and low-cost alternative for fabricating molds for multi-depth PDMS microfluidic devices. (paper)

  19. CO2laser-induced bump formation and growth on polystyrene for multi-depth soft lithography molds

    KAUST Repository

    Li, Huawei

    2012-10-19

    This paper reports the process of creating bumps on the surface of polystyrene (PS) induced by a CO2laser at low powers. The paper also outlines the procedure for growing bumps induced by multiple laser scans on the aforementioned bumps. These bumps result from the net volume gain of the laser heat-affected zone on the PS rather than from a deposition process, and the expansion of the heat-affected zone on PS was verified by measuring the hardness change using nanoindentation. The bumps have a much smoother surface than microchannels fabricated with laser cutting; depending on the laser power, they have heights ranging from hundreds of nanometers to 42m. The laser scanning speed and scan times along with this technique offer a fast and low-cost alternative for fabricating molds for multi-depth PDMS microfluidic devices. © 2012 IOP Publishing Ltd.

  20. Condensation on Slippery Asymmetric Bumps

    Science.gov (United States)

    Park, Kyoo-Chul; Kim, Philseok; Aizenberg, Joanna

    2016-11-01

    Controlling dropwise condensation by designing surfaces that enable droplets to grow rapidly and be shed as quickly as possible is fundamental to water harvesting systems, thermal power generation, distillation towers, etc. However, cutting-edge approaches based on micro/nanoscale textures suffer from intrinsic trade-offs that make it difficult to optimize both growth and transport at once. Here we present a conceptually different design approach based on principles derived from Namib desert beetles, cacti, and pitcher plants that synergistically couples both aspects of condensation and outperforms other synthetic surfaces. Inspired by an unconventional interpretation of the role of the beetle's bump geometry in promoting condensation, we show how to maximize vapor diffusion flux at the apex of convex millimetric bumps by optimizing curvature and shape. Integrating this apex geometry with a widening slope analogous to cactus spines couples rapid drop growth with fast directional transport, by creating a free energy profile that drives the drop down the slope. This coupling is further enhanced by a slippery, pitcher plant-inspired coating that facilitates feedback between coalescence-driven growth and capillary-driven motion. We further observe an unprecedented six-fold higher exponent in growth rate and much faster shedding time compared to other surfaces. We envision that our fundamental understanding and rational design strategy can be applied to a wide range of phase change applications.

  1. Effects of PCB Pad Metal Finishes on the Cu-Pillar/Sn-Ag Micro Bump Joint Reliability of Chip-on-Board (COB) Assembly

    Science.gov (United States)

    Kim, Youngsoon; Lee, Seyong; Shin, Ji-won; Paik, Kyung-Wook

    2016-06-01

    While solder bumps have been used as the bump structure to form the interconnection during the last few decades, the continuing scaling down of devices has led to a change in the bump structure to Cu-pillar/Sn-Ag micro-bumps. Cu-pillar/Sn-Ag micro-bump interconnections differ from conventional solder bump interconnections in terms of their assembly processing and reliability. A thermo-compression bonding method with pre-applied b-stage non-conductive films has been adopted to form solder joints between Cu pillar/Sn-Ag micro bumps and printed circuit board vehicles, using various pad metal finishes. As a result, various interfacial inter-metallic compounds (IMCs) reactions and stress concentrations occur at the Cu pillar/Sn-Ag micro bumps joints. Therefore, it is necessary to investigate the influence of pad metal finishes on the structural reliability of fine pitch Cu pillar/Sn-Ag micro bumps flip chip packaging. In this study, four different pad surface finishes (Thin Ni ENEPIG, OSP, ENEPIG, ENIG) were evaluated in terms of their interconnection reliability by thermal cycle (T/C) test up to 2000 cycles at temperatures ranging from -55°C to 125°C and high-temperature storage test up to 1000 h at 150°C. The contact resistances of the Cu pillar/Sn-Ag micro bump showed significant differences after the T/C reliability test in the following order: thin Ni ENEPIG > OSP > ENEPIG where the thin Ni ENEPIG pad metal finish provided the best Cu pillar/Sn-Ag micro bump interconnection in terms of bump joint reliability. Various IMCs formed between the bump joint areas can account for the main failure mechanism.

  2. Hanford Waste Tank Bump Accident and Consequence Analysis

    International Nuclear Information System (INIS)

    BRATZEL, D.R.

    2000-01-01

    This report provides a new evaluation of the Hanford tank bump accident analysis and consequences for incorporation into the Authorization Basis. The analysis scope is for the safe storage of waste in its current configuration in single-shell and double-shell tanks

  3. Load Express Analysis of the Car Running Against the Bumps in the Road

    Directory of Open Access Journals (Sweden)

    Yu. N. Baryshnikov

    2014-01-01

    Full Text Available In many fields of technology when calculating the strength there are options available to choose design cases and loads in compliance with different operating conditions. In the automotive industry there are no such standards yet. This is due to both a variety of operating conditions, and a complexity of calculating the actual loads.K. Ert`s article is considered to be a pioneering work in this regard. There the author makes a hypothesis of the linear dependence of torque acting on the car, and of the height of bumps in the road. All formulas were obtained for vehicles with the leaf spring suspensions. An appearing entire class of new cars made it necessary to generalize the experience.This paper proposes an engineering method for calculating the vertical loads acting on the car when bumping in the road. We derive general formulas to calculate the height of the road bumps (irregularities on the way of a running car with various types of suspension. A dump truck BELAZ with various types nonlinear of suspension has been used to test the obtained formulas. The results analysis has shown that under equal conditions a car with dependent rear suspension will bear the lower loads than its prototype with a different type of suspension.The paper presents the relationships between the hights of bumps, which cause an equivalent load when different wheels bump against them. It shows a relation between the loads acting on the car when bumping against the same road irregularity by different wheels. The practical significance of the equations is the possibility to calculate loads in various cases in the road using the one-test results. A comparative results analysis of analytical calculation of loads and numerical experiments is based on the nonlinear model of the vehicle.The proposed method is an effective tool for the rapid analysis of loads in the design and fine-tuning the car.

  4. The 1600 Å Emission Bump in Protoplanetary Disks: A Spectral Signature of H2O Dissociation

    Science.gov (United States)

    France, Kevin; Roueff, Evelyne; Abgrall, Hervé

    2017-08-01

    The FUV continuum spectrum of many accreting pre-main sequence stars, Classical T Tauri Stars (CTTSs), does not continue smoothly from the well-studied Balmer continuum emission in the NUV, suggesting that additional processes contribute to the short-wavelength emission in these objects. The most notable spectral feature in the FUV continuum of some CTTSs is a broad emission approximately centered at 1600 Å, which has been referred to as the “1600 Å Bump.” The origin of this feature remains unclear. In an effort to better understand the molecular properties of planet-forming disks and the UV spectral properties of accreting protostars, we have assembled archival FUV spectra of 37 disk-hosting systems observed by the Hubble Space Telescope-Cosmic Origins Spectrograph. Clear 1600 Å Bump emission is observed above the smooth, underlying 1100-1800 Å continuum spectrum in 19/37 Classical T Tauri disks in the HST-COS sample, with the detection rate in transition disks (8/8) being much higher than that in primordial or non-transition sources (11/29). We describe a spectral deconvolution analysis to separate the Bump (spanning 1490-1690 Å) from the underlying FUV continuum, finding an average Bump luminosity L(Bump) ≈ 7 × 1029 erg s-1. Parameterizing the Bump with a combination of Gaussian and polynomial components, we find that the 1600 Å Bump is characterized by a peak wavelength λ o = 1598.6 ± 3.3 Å, with FWHM = 35.8 ± 19.1 Å. Contrary to previous studies, we find that this feature is inconsistent with models of H2 excited by electron -impact. We show that this Bump makes up between 5%-50% of the total FUV continuum emission in the 1490-1690 Å band and emits roughly 10%-80% of the total fluorescent H2 luminosity for stars with well-defined Bump features. Energetically, this suggests that the carrier of the 1600 Å Bump emission is powered by Lyα photons. We argue that the most likely mechanism is Lyα-driven dissociation of H2O in the inner disk, r

  5. Life story chapters, specific memories and the reminiscence bump

    DEFF Research Database (Denmark)

    Thomsen, Dorthe Kirkegaard; Pillemer, David B.; Ivcevic, Zorana

    2011-01-01

    Theories of autobiographical memory posit that extended time periods (here termed chapters) and memories are organised hierarchically. If chapters organise memories and guide their recall, then chapters and memories should show similar temporal distributions over the life course. Previous research...... are over-represented at the beginning of chapters. Potential connections between chapters and the cultural life script are also examined. Adult participants first divided their life story into chapters and identified their most positive and most negative chapter. They then recalled a specific memory from...... demonstrates that positive but not negative memories show a reminiscence bump and that memories cluster at the beginning of extended time periods. The current study tested the hypotheses that (1) ages marking the beginning of positive but not negative chapters produce a bump, and that (2) specific memories...

  6. The Histopathological Investigation of Red and Blue Light Emitting Diode on Treating Skin Wounds in Japanese Big-Ear White Rabbit.

    Directory of Open Access Journals (Sweden)

    Yanhong Li

    Full Text Available The biological effects of different wavelengths of light emitting diode (LED light tend to vary from each other. Research into use of photobiomodulation for treatment of skin wounds and the underlying mechanisms has been largely lacking. We explored the histopathological basis of the therapeutic effect of photobiomodulation and the relation between duration of exposure and photobiomodulation effect of different wavelengths of LED in a Japanese big-ear white rabbit skin-wound model. Skin wound model was established in 16 rabbits (three wounds per rabbit: one served as control, the other two wounds were irradiated by red and blue LED lights, respectively. Rabbits were then divided into 2 equal groups based on the duration of exposure to LED lights (15 and 30 min/exposure. The number of wounds that showed healing and the percentage of healed wound area were recorded. Histopathological examination and skin expression levels of fibroblast growth factor (FGF, epidermal growth factor (EGF, endothelial marker (CD31, proliferating cell nuclear antigen (Ki67 and macrophagocyte (CD68 infiltration, and the proliferation of skin collagen fibers was assessed. On days 16 and 17 of irradiation, the healing rates in red (15 min and 30 min and blue (15 min and 30 min groups were 50%, 37.5%, 25% and 37.5%, respectively, while the healing rate in the control group was 12.5%. The percentage healed area in the red light groups was significantly higher than those in other groups. Collagen fiber and skin thickness were significantly increased in both red light groups; expression of EGF, FGF, CD31 and Ki67 in the red light groups was significantly higher than those in other groups; the expression of FGF in red (30 min group was not significantly different from that in the blue light and control groups. The effect of blue light on wound healing was poorer than that of red light. Red light appeared to hasten wound healing by promoting fibrous tissue, epidermal and

  7. The AGB bump: a calibrator for core mixing

    Directory of Open Access Journals (Sweden)

    Bossini Diego

    2015-01-01

    Full Text Available The efficiency of convection in stars affects many aspects of their evolution and remains one of the key-open questions in stellar modelling. In particular, the size of the mixed core in core-He-burning low-mass stars is still uncertain and impacts the lifetime of this evolutionary phase and, e.g., the C/O profile in white dwarfs. One of the known observables related to the Horizontal Branch (HB and Asymptotic Giant Branch (AGB evolution is the AGB bump. Its luminosity depends on the position in mass of the helium-burning shell at its first ignition, that is affected by the extension of the central mixed region. In this preliminary work we show how various assumptions on near-core mixing and on the thermal stratification in the overshooting region affect the luminosity of the AGB bump, as well as the period spacing of gravity modes in core-He-burning models.

  8. A novel method for direct solder bump pull testing using lead-free solders

    Science.gov (United States)

    Turner, Gregory Alan

    This thesis focuses on the design, fabrication, and evaluation of a new method for testing the adhesion strength of lead-free solders, named the Isotraction Bump Pull method (IBP). In order to develop a direct solder joint-strength testing method that did not require customization for different solder types, bump sizes, specific equipment, or trial-and-error, a combination of two widely used and accepted standards was created. First, solder bumps were made from three types of lead free solder were generated on untreated copper PCB substrates using an in-house fabricated solder bump-on-demand generator, Following this, the newly developed method made use of a polymer epoxy to encapsulate the solder bumps that could then be tested under tension using a high precision universal vertical load machine. The tests produced repeatable and predictable results for each of the three alloys tested that were in agreement with the relative behavior of the same alloys using other testing methods in the literature. The median peak stress at failure for the three solders tested were 2020.52 psi, 940.57 psi, and 2781.0 psi, and were within one standard deviation of the of all data collected for each solder. The assumptions in this work that brittle fracture occurred through the Intermetallic Compound layer (IMC) were validated with the use of Energy-Dispersive X-Ray Spectrometry and high magnification of the fractured surface of both newly exposed sides of the test specimens. Following this, an examination of the process to apply the results from the tensile tests into standard material science equations for the fracture of the systems was performed..

  9. Thermal cycling reliability of Cu/SnAg double-bump flip chip assemblies for 100 μm pitch applications

    Science.gov (United States)

    Son, Ho-Young; Kim, Ilho; Lee, Soon-Bok; Jung, Gi-Jo; Park, Byung-Jin; Paik, Kyung-Wook

    2009-01-01

    A thick Cu column based double-bump flip chip structure is one of the promising alternatives for fine pitch flip chip applications. In this study, the thermal cycling (T/C) reliability of Cu/SnAg double-bump flip chip assemblies was investigated, and the failure mechanism was analyzed through the correlation of T/C test and the finite element analysis (FEA) results. After 1000 thermal cycles, T/C failures occurred at some Cu/SnAg bumps located at the edge and corner of chips. Scanning acoustic microscope analysis and scanning electron microscope observations indicated that the failure site was the Cu column/Si chip interface. It was identified by a FEA where the maximum stress concentration was located during T/C. During T/C, the Al pad between the Si chip and a Cu column bump was displaced due to thermomechanical stress. Based on the low cycle fatigue model, the accumulation of equivalent plastic strain resulted in thermal fatigue deformation of the Cu column bumps and ultimately reduced the thermal cycling lifetime. The maximum equivalent plastic strains of some bumps at the chip edge increased with an increased number of thermal cycles. However, equivalent plastic strains of the inner bumps did not increase regardless of the number of thermal cycles. In addition, the z-directional normal plastic strain ɛ22 was determined to be compressive and was a dominant component causing the plastic deformation of Cu/SnAg double bumps. As the number of thermal cycles increased, normal plastic strains in the perpendicular direction to the Si chip and shear strains were accumulated on the Cu column bumps at the chip edge at low temperature region. Thus it was found that the Al pad at the Si chip/Cu column interface underwent thermal fatigue deformation by compressive normal strain and the contact loss by displacement failure of the Al pad, the main T/C failure mode of the Cu/SnAg flip chip assembly, then occurred at the Si chip/Cu column interface shear strain deformation

  10. Aqueous-based thick photoresist removal for bumping applications

    Science.gov (United States)

    Moore, John C.; Brewer, Alex J.; Law, Alman; Pettit, Jared M.

    2015-03-01

    Cleaning processes account for over 25% of processing in microelectronic manufacturing [1], suggesting electronics to be one of the most chemical intensive markets in commerce. Industry roadmaps exist to reduce chemical exposure, usage, and waste [2]. Companies are encouraged to create a safer working environment, or green factory, and ultimately become certified similar to LEED in the building industry [3]. A significant step in this direction is the integration of aqueous-based photoresist (PR) strippers which eliminate regulatory risks and cut costs by over 50%. One of the largest organic solvent usages is based upon thick PR removal during bumping processes [4-6]. Using market projections and the benefits of recycling, it is estimated that over 1,000 metric tons (mt) of residuals originating from bumping processes are incinerated or sent to a landfill. Aqueous-based stripping would eliminate this disposal while also reducing the daily risks to workers and added permitting costs. Positive-tone PR dissolves in aqueous strippers while negative-tone systems are lifted-off from the substrate, bumps, pillars, and redistribution layers (RDL). While the wafers are further processed and rinsed, the lifted-off PR is pumped from the tank, collected onto a filter, and periodically back-flushed to the trash. The PR solids become a non-hazardous plastic waste while the liquids are mixed with the developer stream, neutralized, filtered, and in most cases, disposed to the sewer. Regardless of PR thickness, removal processes may be tuned to perform in <15min, performing at rates nearly 10X faster than solvents with higher bath lives. A balanced formula is safe for metals, dielectrics, and may be customized to any fab.

  11. Do You Hear a Bump or a Hole?

    DEFF Research Database (Denmark)

    Serafin, Stefania; Turchet, Luca; Nordahl, Rolf

    2010-01-01

    In this paper, we present a preliminary experiment whose goal is to assess the role of temporal aspects in sonically simulating the act of walking on a bump or a hole. In particular, we investigate whether the timing between heel and toe and the timing between footsteps affects the perception...

  12. Dropwise condensation on hydrophobic bumps and dimples

    Science.gov (United States)

    Yao, Yuehan; Aizenberg, Joanna; Park, Kyoo-Chul

    2018-04-01

    Surface topography plays an important role in promoting or suppressing localized condensation. In this work, we study the growth of water droplets on hydrophobic convex surface textures such as bumps and concave surface textures such as dimples with a millimeter scale radius of curvature. We analyze the spatio-temporal droplet size distribution under a supersaturation condition created by keeping the uniform surface temperature below the dew point and show its relationship with the sign and magnitude of the surface curvature. In particular, in contrast to the well-known capillary condensation effect, we report an unexpectedly less favorable condensation on smaller, millimeter-scale dimples where the capillary condensation effect is negligible. To explain these experimental results, we numerically calculated the diffusion flux of water vapor around the surface textures, showing that its magnitude is higher on bumps and lower on dimples compared to a flat surface. We envision that our understanding of millimetric surface topography can be applied to improve the energy efficiency of condensation in applications such as water harvesting, heating, ventilation, and air conditioning systems for buildings and transportation, heat exchangers, thermal desalination plants, and fuel processing systems.

  13. The 1600 Å Emission Bump in Protoplanetary Disks: A Spectral Signature of H{sub 2}O Dissociation

    Energy Technology Data Exchange (ETDEWEB)

    France, Kevin [Laboratory for Atmospheric and Space Physics, University of Colorado, 600 UCB, Boulder, CO 80309 (United States); Roueff, Evelyne; Abgrall, Hervé, E-mail: kevin.france@colorado.edu [LERMA, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Universités, UPMC Univ. Paris 06, F-92190, Meudon (France)

    2017-08-01

    The FUV continuum spectrum of many accreting pre-main sequence stars, Classical T Tauri Stars (CTTSs), does not continue smoothly from the well-studied Balmer continuum emission in the NUV, suggesting that additional processes contribute to the short-wavelength emission in these objects. The most notable spectral feature in the FUV continuum of some CTTSs is a broad emission approximately centered at 1600 Å, which has been referred to as the “1600 Å Bump.” The origin of this feature remains unclear. In an effort to better understand the molecular properties of planet-forming disks and the UV spectral properties of accreting protostars, we have assembled archival FUV spectra of 37 disk-hosting systems observed by the Hubble Space Telescope -Cosmic Origins Spectrograph. Clear 1600 Å Bump emission is observed above the smooth, underlying 1100–1800 Å continuum spectrum in 19/37 Classical T Tauri disks in the HST -COS sample, with the detection rate in transition disks (8/8) being much higher than that in primordial or non-transition sources (11/29). We describe a spectral deconvolution analysis to separate the Bump (spanning 1490–1690 Å) from the underlying FUV continuum, finding an average Bump luminosity L (Bump) ≈ 7 × 10{sup 29} erg s{sup −1}. Parameterizing the Bump with a combination of Gaussian and polynomial components, we find that the 1600 Å Bump is characterized by a peak wavelength λ {sub o} = 1598.6 ± 3.3 Å, with FWHM = 35.8 ± 19.1 Å. Contrary to previous studies, we find that this feature is inconsistent with models of H{sub 2} excited by electron -impact. We show that this Bump makes up between 5%–50% of the total FUV continuum emission in the 1490–1690 Å band and emits roughly 10%–80% of the total fluorescent H{sub 2} luminosity for stars with well-defined Bump features. Energetically, this suggests that the carrier of the 1600 Å Bump emission is powered by Ly α photons. We argue that the most likely mechanism

  14. Early Blue Excess from the Type Ia Supernova 2017cbv and Implications for Its Progenitor

    Energy Technology Data Exchange (ETDEWEB)

    Hosseinzadeh, Griffin; Howell, D. Andrew; McCully, Curtis; Arcavi, Iair [Las Cumbres Observatory, 6740 Cortona Drive, Suite 102, Goleta, CA 93117-5575 (United States); Sand, David J.; Tartaglia, Leonardo [Department of Astronomy/Steward Observatory, 933 North Cherry Avenue, Room N204, Tucson, AZ 85721-0065 (United States); Valenti, Stefano; Bostroem, K. Azalee [Department of Physics, University of California, 1 Shields Avenue, Davis, CA 95616-5270 (United States); Brown, Peter [Mitchell Institute for Fundamental Physics and Astronomy, Texas A and M University, College Station, TX 77843-4242 (United States); Kasen, Daniel [Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720-8169 (United States); Hsiao, Eric Y.; Davis, Scott; Shahbandeh, Melissa [Department of Physics, Florida State University, 77 Chieftain Way, Tallahassee, FL 32306-4350 (United States); Stritzinger, Maximilian D., E-mail: griffin@lco.global [Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark)

    2017-08-20

    We present very early, high-cadence photometric observations of the nearby Type Ia SN 2017cbv. The light curve is unique in that it has a blue bump during the first five days of observations in the U , B , and g bands, which is clearly resolved given our photometric cadence of 5.7 hr during that time span. We model the light curve as the combination of early shocking of the supernova ejecta against a nondegenerate companion star plus a standard SN Ia component. Our best-fit model suggests the presence of a subgiant star 56 R {sub ☉} from the exploding white dwarf, although this number is highly model-dependent. While this model matches the optical light curve well, it overpredicts the observed flux in the ultraviolet bands. This may indicate that the shock is not a blackbody, perhaps because of line blanketing in the UV. Alternatively, it could point to another physical explanation for the optical blue bump, such as interaction with circumstellar material or an unusual nickel distribution. Early optical spectra of SN 2017cbv show strong carbon (C ii λ 6580) absorption up through day −13 with respect to maximum light, suggesting that the progenitor system contains a significant amount of unburned material. These early results on SN 2017cbv illustrate the power of early discovery and intense follow-up of nearby supernovae to resolve standing questions about the progenitor systems and explosion mechanisms of SNe Ia.

  15. Early Blue Excess from the Type Ia Supernova 2017cbv and Implications for Its Progenitor

    International Nuclear Information System (INIS)

    Hosseinzadeh, Griffin; Howell, D. Andrew; McCully, Curtis; Arcavi, Iair; Sand, David J.; Tartaglia, Leonardo; Valenti, Stefano; Bostroem, K. Azalee; Brown, Peter; Kasen, Daniel; Hsiao, Eric Y.; Davis, Scott; Shahbandeh, Melissa; Stritzinger, Maximilian D.

    2017-01-01

    We present very early, high-cadence photometric observations of the nearby Type Ia SN 2017cbv. The light curve is unique in that it has a blue bump during the first five days of observations in the U , B , and g bands, which is clearly resolved given our photometric cadence of 5.7 hr during that time span. We model the light curve as the combination of early shocking of the supernova ejecta against a nondegenerate companion star plus a standard SN Ia component. Our best-fit model suggests the presence of a subgiant star 56 R _☉ from the exploding white dwarf, although this number is highly model-dependent. While this model matches the optical light curve well, it overpredicts the observed flux in the ultraviolet bands. This may indicate that the shock is not a blackbody, perhaps because of line blanketing in the UV. Alternatively, it could point to another physical explanation for the optical blue bump, such as interaction with circumstellar material or an unusual nickel distribution. Early optical spectra of SN 2017cbv show strong carbon (C ii λ 6580) absorption up through day −13 with respect to maximum light, suggesting that the progenitor system contains a significant amount of unburned material. These early results on SN 2017cbv illustrate the power of early discovery and intense follow-up of nearby supernovae to resolve standing questions about the progenitor systems and explosion mechanisms of SNe Ia.

  16. Speed Bump Detection Using Accelerometric Features: A Genetic Algorithm Approach.

    Science.gov (United States)

    Celaya-Padilla, Jose M; Galván-Tejada, Carlos E; López-Monteagudo, F E; Alonso-González, O; Moreno-Báez, Arturo; Martínez-Torteya, Antonio; Galván-Tejada, Jorge I; Arceo-Olague, Jose G; Luna-García, Huizilopoztli; Gamboa-Rosales, Hamurabi

    2018-02-03

    Among the current challenges of the Smart City, traffic management and maintenance are of utmost importance. Road surface monitoring is currently performed by humans, but the road surface condition is one of the main indicators of road quality, and it may drastically affect fuel consumption and the safety of both drivers and pedestrians. Abnormalities in the road, such as manholes and potholes, can cause accidents when not identified by the drivers. Furthermore, human-induced abnormalities, such as speed bumps, could also cause accidents. In addition, while said obstacles ought to be signalized according to specific road regulation, they are not always correctly labeled. Therefore, we developed a novel method for the detection of road abnormalities (i.e., speed bumps). This method makes use of a gyro, an accelerometer, and a GPS sensor mounted in a car. After having the vehicle cruise through several streets, data is retrieved from the sensors. Then, using a cross-validation strategy, a genetic algorithm is used to find a logistic model that accurately detects road abnormalities. The proposed model had an accuracy of 0.9714 in a blind evaluation, with a false positive rate smaller than 0.018, and an area under the receiver operating characteristic curve of 0.9784. This methodology has the potential to detect speed bumps in quasi real-time conditions, and can be used to construct a real-time surface monitoring system.

  17. Classical propagation of strings across a big crunch/big bang singularity

    International Nuclear Information System (INIS)

    Niz, Gustavo; Turok, Neil

    2007-01-01

    One of the simplest time-dependent solutions of M theory consists of nine-dimensional Euclidean space times 1+1-dimensional compactified Milne space-time. With a further modding out by Z 2 , the space-time represents two orbifold planes which collide and re-emerge, a process proposed as an explanation of the hot big bang [J. Khoury, B. A. Ovrut, P. J. Steinhardt, and N. Turok, Phys. Rev. D 64, 123522 (2001).][P. J. Steinhardt and N. Turok, Science 296, 1436 (2002).][N. Turok, M. Perry, and P. J. Steinhardt, Phys. Rev. D 70, 106004 (2004).]. When the two planes are near, the light states of the theory consist of winding M2-branes, describing fundamental strings in a particular ten-dimensional background. They suffer no blue-shift as the M theory dimension collapses, and their equations of motion are regular across the transition from big crunch to big bang. In this paper, we study the classical evolution of fundamental strings across the singularity in some detail. We also develop a simple semiclassical approximation to the quantum evolution which allows one to compute the quantum production of excitations on the string and implement it in a simplified example

  18. The first bump-bonded pixel detectors on CVD diamond

    International Nuclear Information System (INIS)

    Adam, W.; Bauer, C.; Berdermann, E.; Bergonzo, P.; Bogani, F.; Borchi, E.; Brambilla, A.; Bruzzi, M.; Colledani, C.; Conway, J.; Dabrowski, W.; Delpierre, P.; Deneuville, A.; Dulinski, W.; Eijk, B. van; Fallou, A.; Fizzotti, F.; Foulon, F.; Friedl, M.; Gan, K.K.; Gheeraert, E.; Grigoriev, E.; Hallewell, G.; Hall-Wilton, R.; Han, S.; Hartjes, F.; Hrubec, J.; Husson, D.; Kagan, H.; Kania, D.; Kaplon, J.; Karl, C.; Kass, R.; Krammer, M.; Logiudice, A.; Lu, R.; Manfredi, P.F.; Manfredotti, C.; Marshall, R.D.; Meier, D.; Mishina, M.; Oh, A.; Palmieri, V.G.; Pan, L.S.; Peitz, A.; Pernicka, M.; Pirollo, S.; Polesello, P.; Pretzl, K.; Re, V.; Riester, J.L.; Roe, S.; Roff, D.; Rudge, A.; Schnetzer, S.; Sciortino, S.; Speziali, V.; Stelzer, H.; Steuerer, J.; Stone, R.; Tapper, R.J.; Tesarek, R.; Trawick, M.; Trischuk, W.; Turchetta, R.; Vittone, E.; Wagner, A.; Walsh, A.M.; Wedenig, R.; Weilhammer, P.; Zeuner, W.; Ziock, H.; Zoeller, M.; Charles, E.; Ciocio, A.; Dao, K.; Einsweiler, K.; Fasching, D.; Gilchriese, M.; Joshi, A.; Kleinfelder, S.; Milgrome, O.; Palaio, N.; Richardson, J.; Sinervo, P.; Zizka, G.

    1999-01-01

    Diamond is a nearly ideal material for detecting ionising radiation. Its outstanding radiation hardness, fast charge collection and low leakage current allow it to be used in high radiation environments. These characteristics make diamond sensors particularly appealing for use in the next generation of pixel detectors. Over the last year, the RD42 collaboration has worked with several groups that have developed pixel readout electronics in order to optimise diamond sensors for bump-bonding. This effort resulted in an operational diamond pixel sensor that was tested in a pion beam. We demonstrate that greater than 98% of the channels were successfully bump-bonded and functioning. The device shows good overall hit efficiency as well as clear spatial hit correlation to tracks measured in a silicon reference telescope. A position resolution of 14.8 μm was observed, consistent with expectations given the detector pitch

  19. The first bump-bonded pixel detectors on CVD diamond

    CERN Document Server

    Adam, W; Berdermann, E; Bergonzo, P; Bogani, F; Borchi, E; Brambilla, A; Bruzzi, Mara; Colledani, C; Conway, J; Dabrowski, W; Delpierre, P A; Deneuville, A; Dulinski, W; van Eijk, B; Fallou, A; Fizzotti, F; Foulon, F; Fried, M; Gan, K K; Gheeraert, E; Grigoriev, E; Hallewell, G D; Hall-Wilton, R; Han, S; Hartjes, F G; Hrubec, Josef; Husson, D; Kagan, H; Kania, D R; Kaplon, J; Karl, C; Kass, R; Krammer, Manfred; Lo Giudice, A; Lü, R; Manfredi, P F; Manfredotti, C; Marshall, R D; Meier, D; Mishina, M; Oh, A; Palmieri, V G; Pan, L S; Peitz, A; Pernicka, Manfred; Pirollo, S; Polesello, P; Pretzl, Klaus P; Re, V; Riester, J L; Roe, S; Roff, D G; Rudge, A; Schnetzer, S R; Sciortino, S; Speziali, V; Stelzer, H; Steuerer, J; Stone, R; Tapper, R J; Tesarek, R J; Trawick, M L; Trischuk, W; Turchetta, R; Vittone, E; Wagner, A; Walsh, A M; Wedenig, R; Weilhammer, Peter; Zeuner, W; Ziock, H J; Zöller, M; Charles, E; Ciocio, A; Dao, K; Einsweiler, Kevin F; Fasching, D; Gilchriese, M G D; Joshi, A; Kleinfelder, S A; Milgrome, O; Palaio, N; Richardson, J; Sinervo, P K; Zizka, G

    1999-01-01

    Diamond is a nearly ideal material for detecting ionising radiation. Its outstanding radiation hardness, fast charge collection and low leakage current allow it to be used in high radiation environments. These characteristics make diamond sensors particularly appealing for use in the next generation of pixel detectors. Over the last year, the RD42 collaboration has worked with several groups that have developed pixel readout electronics in order to optimise diamond sensors for bump-bonding. This effort resulted in an operational diamond pixel sensor that was tested in a pion beam. We demonstrate that greater than 98565544f the channels were successfully bump-bonded and functioning. The device shows good overall hit efficiency as well as clear spatial hit correlation to tracks measured in a silicon reference telescope. A position resolution of 14.8 mu m was observed, consistent with expectations given the detector pitch. (13 refs).

  20. The first bump-bonded pixel detectors on CVD diamond

    Energy Technology Data Exchange (ETDEWEB)

    Adam, W.; Bauer, C.; Berdermann, E.; Bergonzo, P.; Bogani, F.; Borchi, E.; Brambilla, A.; Bruzzi, M.; Colledani, C.; Conway, J.; Dabrowski, W.; Delpierre, P.; Deneuville, A.; Dulinski, W.; Eijk, B. van; Fallou, A.; Fizzotti, F.; Foulon, F.; Friedl, M.; Gan, K.K.; Gheeraert, E.; Grigoriev, E.; Hallewell, G.; Hall-Wilton, R.; Han, S.; Hartjes, F.; Hrubec, J.; Husson, D.; Kagan, H.; Kania, D.; Kaplon, J.; Karl, C.; Kass, R.; Krammer, M.; Logiudice, A.; Lu, R.; Manfredi, P.F.; Manfredotti, C.; Marshall, R.D.; Meier, D.; Mishina, M.; Oh, A.; Palmieri, V.G.; Pan, L.S.; Peitz, A.; Pernicka, M.; Pirollo, S.; Polesello, P.; Pretzl, K.; Re, V.; Riester, J.L.; Roe, S.; Roff, D.; Rudge, A.; Schnetzer, S.; Sciortino, S.; Speziali, V.; Stelzer, H.; Steuerer, J.; Stone, R.; Tapper, R.J.; Tesarek, R.; Trawick, M.; Trischuk, W. E-mail: william@physics.utoronto.ca; Turchetta, R.; Vittone, E.; Wagner, A.; Walsh, A.M.; Wedenig, R.; Weilhammer, P.; Zeuner, W.; Ziock, H.; Zoeller, M.; Charles, E.; Ciocio, A.; Dao, K.; Einsweiler, K.; Fasching, D.; Gilchriese, M.; Joshi, A.; Kleinfelder, S.; Milgrome, O.; Palaio, N.; Richardson, J.; Sinervo, P.; Zizka, G

    1999-11-01

    Diamond is a nearly ideal material for detecting ionising radiation. Its outstanding radiation hardness, fast charge collection and low leakage current allow it to be used in high radiation environments. These characteristics make diamond sensors particularly appealing for use in the next generation of pixel detectors. Over the last year, the RD42 collaboration has worked with several groups that have developed pixel readout electronics in order to optimise diamond sensors for bump-bonding. This effort resulted in an operational diamond pixel sensor that was tested in a pion beam. We demonstrate that greater than 98% of the channels were successfully bump-bonded and functioning. The device shows good overall hit efficiency as well as clear spatial hit correlation to tracks measured in a silicon reference telescope. A position resolution of 14.8 {mu}m was observed, consistent with expectations given the detector pitch.

  1. Discovery of an Unexplored Protein Structural Scaffold of Serine Protease from Big Blue Octopus (Octopus cyanea): A New Prospective Lead Molecule.

    Science.gov (United States)

    Panda, Subhamay; Kumari, Leena

    2017-01-01

    Serine proteases are a group of enzymes that hydrolyses the peptide bonds in proteins. In mammals, these enzymes help in the regulation of several major physiological functions such as digestion, blood clotting, responses of immune system, reproductive functions and the complement system. Serine proteases obtained from the venom of Octopodidae family is a relatively unexplored area of research. In the present work, we tried to effectively utilize comparative composite molecular modeling technique. Our key aim was to propose the first molecular model structure of unexplored serine protease 5 derived from big blue octopus. The other objective of this study was to analyze the distribution of negatively and positively charged amino acid over molecular modeled structure, distribution of secondary structural elements, hydrophobicity molecular surface analysis and electrostatic potential analysis with the aid of different bioinformatic tools. In the present study, molecular model has been generated with the help of I-TASSER suite. Afterwards the refined structural model was validated with standard methods. For functional annotation of protein molecule we used Protein Information Resource (PIR) database. Serine protease 5 of big blue octopus was analyzed with different bioinformatical algorithms for the distribution of negatively and positively charged amino acid over molecular modeled structure, distribution of secondary structural elements, hydrophobicity molecular surface analysis and electrostatic potential analysis. The functionally critical amino acids and ligand- binding site (LBS) of the proteins (modeled) were determined using the COACH program. The molecular model data in cooperation to other pertinent post model analysis data put forward molecular insight to proteolytic activity of serine protease 5, which helps in the clear understanding of procoagulant and anticoagulant characteristics of this natural lead molecule. Our approach was to investigate the octopus

  2. From Big Data to Big Displays High-Performance Visualization at Blue Brain

    KAUST Repository

    Eilemann, Stefan

    2017-10-19

    Blue Brain has pushed high-performance visualization (HPV) to complement its HPC strategy since its inception in 2007. In 2011, this strategy has been accelerated to develop innovative visualization solutions through increased funding and strategic partnerships with other research institutions. We present the key elements of this HPV ecosystem, which integrates C++ visualization applications with novel collaborative display systems. We motivate how our strategy of transforming visualization engines into services enables a variety of use cases, not only for the integration with high-fidelity displays, but also to build service oriented architectures, to link into web applications and to provide remote services to Python applications.

  3. NSRL Extraction Bump Control in the Booster

    International Nuclear Information System (INIS)

    Brennan, L.

    2008-01-01

    Due to inadequacies in the user interface of the booster orbit control system, a number of new tools were developed. The first priority was an accurate calculation of the winding currents given specific displacements at each extraction septa. Next, the physical limits of the power supplies (±600 amps) needed to be taken into account. In light of this limit, a system is developed that indicates to the user what the allowed values of one bump parameter are once the other two have been specified. Finally, techniques are developed to account for the orbit behavior once power supplies are requested to exceed their ±600 amp limit. This includes a recalculation of bump parameters and a calculation of the amplitude of the residuals. Following this, possible areas for further development are outlined. These techniques were computationally developed in Mathematica and tested in the Methodical Accelerator Design (MAD) program before they were implemented into the control system. At the end, a description of the implementation of these techniques in a new interface is described. This includes a depiction of the appearance and functionality of the graphical user interface, a description of the input and output flow, and an outline of how each important calculation is performed

  4. Revised masses for the double-mode and bump Cepheids

    International Nuclear Information System (INIS)

    Cox, A.N.; Deupree, R.G.; King, D.S.; Hodson, S.W.

    1977-01-01

    We consider Population I Cepheids with two pulsation modes and those with a bump in the light and velocity curves. Model envelopes for these Cepheids have been altered in several ways in an attempt in remove the discrepancy between masses predicted from the evolution theory mass-luminosity relation an th masses predicted from pulsation theory. One of these ways, the inclusion of rotation, does not change the period ratio of the first overtone mode to the fundamental mode enough to resolve this mass discrepancy. Another way, the inclusion of a helium- (or metal-) rich layer mixed by convection and pulsation between the stellar surface and 70,000 K decreases this period ratio appreciably. The ratio of the second overtone period to the fundamental period is also reduced with this structure. The masses of the double-mode Cepheids U TrA and V367 Sct and the bump Cepheids U Sgr and β Dor are found to be much closer to the masses derived from stellar evolution theory

  5. Biomimetic Water-Collecting Fabric with Light-Induced Superhydrophilic Bumps.

    Science.gov (United States)

    Wang, Yuanfeng; Wang, Xiaowen; Lai, Chuilin; Hu, Huawen; Kong, Yeeyee; Fei, Bin; Xin, John H

    2016-02-10

    To develop an efficient water-collecting surface that integrates both fast water-capturing and easy drainage properties is of high current interest for addressing global water issues. In this work, a superhydrophobic surface was fabricated on cotton fabric via manipulation of both the surface roughness and surface energy. This was followed by a subsequent spray coating of TiO2 nanosol that created light-induced superhydrophilic bumps with a unique raised structure as a result of the interfacial tension of the TiO2 nanosol sprayed on the superhydrophobic fiber surface. These raised TiO2 bumps induce both a wettability gradient and a shape gradient, synergistically accelerating water coalescence and water collection. The in-depth study revealed that the quantity and the distribution of the TiO2 had a significant impact on the final water collection efficiency. This inexpensive and facilely fabricated fabric biomimicks the desert beetle's back and spider silk, which are capable of fog harvesting without additional energy consumption.

  6. Dietary low-dose sucrose modulation of IQ-induced genotoxicity in the colon and liver of Big Blue((TM)) rats

    DEFF Research Database (Denmark)

    Moller, P.; Hansen, Max; Autrup, H.

    2003-01-01

    Earlier studies have indicated that sucrose increases 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced aberrant crypt foci in the colon. In this study, we investigated the role of sucrose in IQ-induced genotoxicity of the colon mucosa and liver. Big Blue(TM) rats were fed with IQ (20 ppm...... in feed) and/or sucrose (3.45 or 6.85 wt.% in feed) for 3 weeks. IQ increased DNA strand breaks in the colon, whereas the mutation frequency was increased in the liver. The level of IQ-induced DNA adducts was elevated in both colon mucosa cells and liver. In the liver, high sucrose intake increased...... the level of DNA adducts above that of IQ and low sucrose intake. Oxidative DNA damage detected in terms of 7-hydro-8-oxo-2'-deoxyguanosine by HPLC-EC, or endonuclease HI or formamidopyrimidine DNA glycosylase sensitive sites were unaltered in the colon and liver. Expression of ERCC1 and OGG1 mRNA levels...

  7. Speed Bump Detection Using Accelerometric Features: A Genetic Algorithm Approach

    Directory of Open Access Journals (Sweden)

    Jose M. Celaya-Padilla

    2018-02-01

    Full Text Available Among the current challenges of the Smart City, traffic management and maintenance are of utmost importance. Road surface monitoring is currently performed by humans, but the road surface condition is one of the main indicators of road quality, and it may drastically affect fuel consumption and the safety of both drivers and pedestrians. Abnormalities in the road, such as manholes and potholes, can cause accidents when not identified by the drivers. Furthermore, human-induced abnormalities, such as speed bumps, could also cause accidents. In addition, while said obstacles ought to be signalized according to specific road regulation, they are not always correctly labeled. Therefore, we developed a novel method for the detection of road abnormalities (i.e., speed bumps. This method makes use of a gyro, an accelerometer, and a GPS sensor mounted in a car. After having the vehicle cruise through several streets, data is retrieved from the sensors. Then, using a cross-validation strategy, a genetic algorithm is used to find a logistic model that accurately detects road abnormalities. The proposed model had an accuracy of 0.9714 in a blind evaluation, with a false positive rate smaller than 0.018, and an area under the receiver operating characteristic curve of 0.9784. This methodology has the potential to detect speed bumps in quasi real-time conditions, and can be used to construct a real-time surface monitoring system.

  8. Aging treatment characteristics of solder bump joint for high reliability optical module

    International Nuclear Information System (INIS)

    Kim, Kyung-Seob; Yu, Chung-Hee; Yang, Jun-Mo

    2004-01-01

    The joint strength and fracture surfaces of Sn-37 mass% Pb and Au stud bumps for photo diode packages after isothermal aging testing were studied experimentally. Al/Au stud bumps and Cu/Sn-37 mass% Pb solders were adopted, and aged for up to 900 h to analyze the effect of intermetallic compound (IMC). The joint strength decreased with aging time. The diffraction patterns of Cu 6 Sn 5 , scallop-shaped IMCs, and planar-shaped Cu 3 Sn were characterized using transmission electron microscopy (TEM). The formation of Kirkendall voids and the growth of IMCs at the solder were found to be a possible mechanism for joint strength reduction

  9. BLUE OCEAN STRATEGY (BOS SEBAGAI PARADIGMA BARU MANAJEMEN PENDIDIKAN ISLAM

    Directory of Open Access Journals (Sweden)

    Ikhwan Fuad

    2016-08-01

    Full Text Available The focus of this article is to describe the Blue Ocean Strategy as a new paradigm of Islamic education management. the author seeks to elaborate on how the adoption of the Blue Ocean strategy of the business world to the world of education and answered the principles of what is accepted and rejected away from the theory. Adoption of blue ocean strategy is done by applying the universal principles are : among others reconstruct market boundaries, focus on the big picture rather than numbers, reach beyond existing demand, perform a series of strategies with appropriate, efforts to overcome organizational constraints and integrate execution into strategy. The principles of Blue Ocean Strategy Indicators that can be absorbed is an indicator that focuses gave excellent service and were not absorbed is a strong indicator of economic motivation. Generally, Blue Ocean Strategy quite well applied as a management paradigm of Islamic education.

  10. The reminiscence bump for public events: A review of its prevalence and taxonomy of alternative age distributions

    DEFF Research Database (Denmark)

    Koppel, Jonathan Mark

    2013-01-01

    a legitimate effect, and (ii) the alternative age distributions that are otherwise seen in recall for public events. I conclude that, though the bump is frequently found, the legitimacy of the effect is contingent upon the strictness of the standard one employs. I also find significant exceptions to the bump...

  11. GIANT X-RAY BUMP IN GRB 121027A: EVIDENCE FOR FALL-BACK DISK ACCRETION

    Energy Technology Data Exchange (ETDEWEB)

    Wu Xuefeng [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China); Hou Shujin [Department of Astronomy and Institute of Theoretical Physics and Astrophysics, Xiamen University, Xiamen, Fujian 361005 (China); Lei Weihua, E-mail: xfwu@pmo.ac.cn, E-mail: leiwh@hust.edu.cn [School of Physics, Huazhong University of Science and Technology, Wuhan 430074 (China)

    2013-04-20

    A particularly interesting discovery in observations of GRB 121027A is that of a giant X-ray bump detected by the Swift/X-Ray Telescope. The X-ray afterglow re-brightens sharply at {approx}10{sup 3} s after the trigger by more than two orders of magnitude in less than 200 s. This X-ray bump lasts for more than 10{sup 4} s. It is quite different from typical X-ray flares. In this Letter we propose a fall-back accretion model to interpret this X-ray bump within the context of the collapse of a massive star for a long-duration gamma-ray burst. The required fall-back radius of {approx}3.5 Multiplication-Sign 10{sup 10} cm and mass of {approx}0.9-2.6 M{sub Sun} imply that a significant part of the helium envelope should survive through the mass loss during the last stage of the massive progenitor of GRB 121027A.

  12. TRACKING TESTS FOR THE SNS FAST INJECTION BUMP POWER SUPPLY

    International Nuclear Information System (INIS)

    ENG, W.; CUTLER, R.; DEWAN, S.

    2004-01-01

    The tracking requirement of the SNS Fast Injection Bump power supplies is described. In addition to the usual tracking between the load current and the input reference of a power supply, these power supplies must also track between pairs of units under slightly different loads. This paper describes the use of a current-null test to measure tracking performances. For the actual tests, a single dummy magnet load was used to measure the tracking between the first two production units at the manufacturer's facility. Using the Yokogawa WE7000 waveform. PC-based measurement instrument, input and output waveforms are digitized and stored in data files. A program written for this application is then used to extract data from these files to construct, analyze the waveforms and characterize the power supply performance. Results of the measurements of two SNS Fast Injection Bump power supplies will be presented in this paper

  13. Reading in Middle School: Bumps in the Literacy Crossroads

    Science.gov (United States)

    Hall, Katrina Willard

    2008-01-01

    Certainly a major bump in the literacy road today is the apparent conflict between school literacies and the preferred literacy activities of students outside of school. After family conversation about a nephew who was getting poor grades in language arts, Hall shares her thinking on the dilemmas of what constitutes literacy, how literacies kids…

  14. Decomposing the sales promotion bump accounting for cross-category effects

    NARCIS (Netherlands)

    Leeflang, Peter S. H.; Selva, Josefa Parreno; Wittink, Dick R.; Dijk, Albertus Alard van

    Extant research on the decomposition of unit sales bumps due to price promotions considers these effects only within a single product category. This article introduces a framework that accommodates specific cross-category effects. Empirical results based on daily data measured at the item/SKU level

  15. Numerical Analysis of Warpage Induced by Thermo-Compression Bonding Process of Cu Pillar Bump Flip Chip Package

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Oh Young; Jung, Hoon Sun; Lee, Jung Hoon; Choa, Sung-Hoon [Seoul Nat’l Univ. of Science and Technology, Seoul (Korea, Republic of)

    2017-06-15

    In flip chip technology, the conventional solder bump has been replaced with a copper (Cu) pillar bump owing to its higher input/output (I/O) density, finer pitch, and higher reliability. However, Cu pillar bump technology faces several issues, such as interconnect shorting and higher low-k stress due to stiffer Cu pillar structure when the conventional reflow process is used. Therefore, the thermal compression bonding (TCB) process has been adopted in the flip chip attachment process in order to reduce the package warpage and stress. In this study, we investigated the package warpage induced during the TCB process using a numerical analysis. The warpage of the TCB process was compared with that of the reflow process.

  16. Big is not always beautiful - small can be a short cut to blue oceans

    DEFF Research Database (Denmark)

    Kvistgaard, Peter

    2007-01-01

    Often it is claimed that big investments are the only way to success in tourism and the experience economy. Only by building some of the world's biggest hotels - like the ones in Dubai or Las Vegas where hotels with 3-4,000 rooms are not uncommon - success can be achieved. It is understandable...... that hotels have to be big in Las Vegas in order to secure a good return on investment. It is also understandable that they build big hotels when 37 million people came to visit and 22,000 conventions were held in Las Vegas in 2004 according to the official website of Las Vegas (www.lasvegasnevada.gov/factsstatistics/funfacts.htm)....

  17. The BUMP model of response planning: intermittent predictive control accounts for 10 Hz physiological tremor.

    Science.gov (United States)

    Bye, Robin T; Neilson, Peter D

    2010-10-01

    Physiological tremor during movement is characterized by ∼10 Hz oscillation observed both in the electromyogram activity and in the velocity profile. We propose that this particular rhythm occurs as the direct consequence of a movement response planning system that acts as an intermittent predictive controller operating at discrete intervals of ∼100 ms. The BUMP model of response planning describes such a system. It forms the kernel of Adaptive Model Theory which defines, in computational terms, a basic unit of motor production or BUMP. Each BUMP consists of three processes: (1) analyzing sensory information, (2) planning a desired optimal response, and (3) execution of that response. These processes operate in parallel across successive sequential BUMPs. The response planning process requires a discrete-time interval in which to generate a minimum acceleration trajectory to connect the actual response with the predicted future state of the target and compensate for executional error. We have shown previously that a response planning time of 100 ms accounts for the intermittency observed experimentally in visual tracking studies and for the psychological refractory period observed in double stimulation reaction time studies. We have also shown that simulations of aimed movement, using this same planning interval, reproduce experimentally observed speed-accuracy tradeoffs and movement velocity profiles. Here we show, by means of a simulation study of constant velocity tracking movements, that employing a 100 ms planning interval closely reproduces the measurement discontinuities and power spectra of electromyograms, joint-angles, and angular velocities of physiological tremor reported experimentally. We conclude that intermittent predictive control through sequential operation of BUMPs is a fundamental mechanism of 10 Hz physiological tremor in movement. Copyright © 2010 Elsevier B.V. All rights reserved.

  18. Trapping saturation of the bump-on-tail instability and electrostatic harmonic excitation in Earth's foreshock

    International Nuclear Information System (INIS)

    Klimas, A.J.

    1990-01-01

    Trapping saturation of the bump-on-tail instability is discussed using electron plasma Vlasov simulation results. The role of electrostatic harmonic excitation is considered in detail and shown to play a decisive role in the saturation of the instability. An extensive discussion of the simulation results is given to show that the results are not significantly limited by the finite number of Fourier modes used nor by the discrete distribution of those modes in wave number. It is argued that in the leading edge of Earth's electron foreshock a narrow wave number band of unstable field modes leads to trapping saturation of the bump-on-tail instability while simultaneously exciting electrostatic plasma waves at harmonics of the plasma frequency in simialr narrow bands of shorter wavelengths. The argument is based (1) on the observations of Lacombe et al. (1985), who found intense plasma waves at the leading edge of the foreshock with a spectral distribution sufficiently narrow to trap particles in resonance with the waves, and (2) on numerical simulations of the foreshock electron plasma which indicate that trapping saturation of the bump-on-tail instability leads to phase space vortex formation with consequent excitation of electrostatic harmonics. Thus it is suggested that observations of electrostatic harmonics in the leading edge of the foreshock would strongly implicate trapping as the saturation mechanism for the bump-on-tail instability in that region

  19. Planetesimal formation by an axisymmetric radial bump of the column density of the gas in a protoplanetary disk

    Science.gov (United States)

    Onishi, Isamu K.; Sekiya, Minoru

    2017-04-01

    We investigate the effect of a radial pressure bump in a protoplanetary disk on planetesimal formation. We performed the two-dimensional numerical simulation of the dynamical interaction of solid particles and gas with an initially defined pressure bump under the assumption of axisymmetry. The aim of this work is to elucidate the effects of the stellar vertical gravity that were omitted in a previous study. Our results are very different from the previous study, which omitted the vertical gravity. Because dust particles settle toward the midplane because of the vertical gravity to form a thin dust layer, the regions outside of the dust layer are scarcely affected by the back-reaction of the dust. Hence, the gas column density keeps its initial profile with a bump, and dust particles migrate toward the bump. In addition, the turbulence due to the Kelvin-Helmholtz instability caused by the difference of the azimuthal velocities between the inside and outside of the dust layer is suppressed where the radial pressure gradient is reduced by the pressure bump. The dust settling proceeds further where the turbulence is weak, and a number of dust clumps are formed. The dust density in some clumps exceeds the Roche density. Planetesimals are considered to be formed from these clumps owing to the self-gravity.[Figure not available: see fulltext.

  20. Bumps, breathers, and waves in a neural network with spike frequency adaptation

    International Nuclear Information System (INIS)

    Coombes, S.; Owen, M.R.

    2005-01-01

    We introduce a continuum model of neural tissue that includes the effects of spike frequency adaptation (SFA). The basic model is an integral equation for synaptic activity that depends upon nonlocal network connectivity, synaptic response, and the firing rate of a single neuron. We consider a phenomenological model of SFA via a simple state-dependent threshold firing rate function. As without SFA, Mexican-hat connectivity allows for the existence of spatially localized states (bumps). Importantly recent Evans function techniques are used to show that bumps may destabilize leading to the emergence of breathers and traveling waves. Moreover, a similar analysis for traveling pulses leads to the conditions necessary to observe a stable traveling breather. Simulations confirm our theoretical predictions and illustrate the rich behavior of this model

  1. Trapping saturation of the bump-on-tail instability and electrostatic harmonic excitation in earth's foreshock

    Science.gov (United States)

    Klimas, Alexander J.

    1990-01-01

    The Vlasov simulation is used to examine the trapping saturation of the bump-on-tail instability both with and without mode-mode coupling and subsequent harmonic excitation. It is found that adding the pumped harmonic modes leads to a significant difference in the behavior of the phase-space distribution function near the unstable bump at the saturation time of the instability. The pumped modes permit rapid plateau formation on the space-averaged velocity distribution, in effect preventing the onset of the quasi-linear velocity-diffusion saturation mechanism.

  2. Ship Track for Investigating the Charleston Bump 2003 - Office of Ocean Exploration

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Ship track of the R/V Seward Johnson during the "Investigating the Charleston Bump 2003" expedition sponsored by the National Oceanic and Atmospheric Administration...

  3. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of big blue® rats.

    Science.gov (United States)

    Thompson, Chad M; Young, Robert R; Dinesdurage, Harshini; Suh, Mina; Harris, Mark A; Rohr, Annette C; Proctor, Deborah M

    2017-09-01

    A cancer bioassay on hexavalent chromium Cr(VI) in drinking water reported increased incidences of duodenal tumors in B6C3F1 mice at exposures of 30-180ppm, and oral cavity tumors in F344 rats at 180ppm. A subsequent transgenic rodent (TGR) in vivo mutation assay in Big Blue® TgF344 rats found that exposure to 180ppm Cr(VI) in drinking water for 28days did not increase cII transgene mutant frequency (MF) in the oral cavity (Thompson et al., 2015). Herein, we extend our analysis to the duodenum of these same TgF344 rats. At study termination, duodenum chromium levels were below either the limit of detection or quantification in control rats, but were 24.6±3.8μg/g in Cr(VI)-treated rats. The MF in control (23.2×10 -6 ) and Cr(VI)-treated rats (22.7×10 -6 ) were nearly identical. In contrast, the MF in the duodenum of rats exposed to 1-ethyl-1-nitrosourea for six days (study days 1, 2, 3, 12, 19, 26) increased 24-fold to 557×10 -6 . These findings indicate that mutagenicity is unlikely an early initiating event in Cr(VI)-induced intestinal carcinogenesis. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Misuse of speed-bumps on two-lane main rural roads. A generalized practice in Venezuela

    Energy Technology Data Exchange (ETDEWEB)

    Calderas Volcanes, R.J.; Moreno Gonzalez, E.G.

    2016-07-01

    Settlements of uncontrolled population on side of road in Venezuela originate the excessive use of traffic speed reducers to mitigate accidents. Misuse of these speed control devices generate problem of functionality in the two-lane main rural roads which requires to be studied to demonstrate its effect on the capacity and level of service. Although other factors may occur (i.e, environmental problems and health), the disproportionate use of speed-bumps worsens circulation quality by increase of travel time as most sensitive parameter. Where this effect not can be reversed it should be made efforts to mitigate speed using another traffic-calming device. The studied stretches are selected according to particular characteristics such as: urban settlement, isolated speed-bump and its installation in series, including case without speed-bumps which guarantees the proper contrast. Video cameras to detect the travel time of vehicles are used in each road section, it allow the measures of other parameters. The travel time distribution with or without speed-bumps and probability distribution that characterizes vehicle movement in each stretch allows the simulation and modeling with the ARENA software. Travel time allows obtain the speed which, together with the volume of traffic, determines the level of service according to the Highway Capacity Manual criterion. The economic cost of substitute measures versus travel time is evaluated and may be useful in decision-making or implementation of better policies by transport governmental institutions. (Author)

  5. Pressure bump instability in very large cold bore storage rings

    International Nuclear Information System (INIS)

    Limon, P.

    1983-12-01

    Calculations have been done to estimate the circulating current necessary to induce the onset of a pressure bump instability in a cold bore storage ring. For a wide range of storage ring parameters, the instability threshold current is more than an order of magnitude higher than the operating current. 4 references, 2 tables

  6. Application of the adjoint optimisation of shock control bump for ONERA-M6 wing

    Science.gov (United States)

    Nejati, A.; Mazaheri, K.

    2017-11-01

    This article is devoted to the numerical investigation of the shock wave/boundary layer interaction (SWBLI) as the main factor influencing the aerodynamic performance of transonic bumped airfoils and wings. The numerical analysis is conducted for the ONERA-M6 wing through a shock control bump (SCB) shape optimisation process using the adjoint optimisation method. SWBLI is analyzed for both clean and bumped airfoils and wings, and it is shown how the modified wave structure originating from upstream of the SCB reduces the wave drag, by improving the boundary layer velocity profile downstream of the shock wave. The numerical simulation of the turbulent viscous flow and a gradient-based adjoint algorithm are used to find the optimum location and shape of the SCB for the ONERA-M6 airfoil and wing. Two different geometrical models are introduced for the 3D SCB, one with linear variations, and another with periodic variations. Both configurations result in drag reduction and improvement in the aerodynamic efficiency, but the periodic model is more effective. Although the three-dimensional flow structure involves much more complexities, the overall results are shown to be similar to the two-dimensional case.

  7. Detection of bump-on-tail reduced electron velocity distributions at the electron foreshock boundary

    International Nuclear Information System (INIS)

    Fitzenreiter, R.J.; Klimas, A.J.; Scudder, J.D.

    1984-02-01

    Reduced velocity distributions are derived from three-dimensional measurements of the velocity distribution of electrons in the 7 to 500 eV range in the electron foreshock. Bump-on-tail reduced distributions are presented for the first time at the foreshock boundary consistent with Filbert and Kellogg's proposed time-of-flight mechanism for generating the electron beams. In a significant number of boundary crossings, bump-on-tail reduced distributions were found in consecutive 3 sec measurements made 9 sec apart. It is concluded that, although the beams are linearly unstable to plasma waves according to the Penrose criterion, they persist on a time scale of 3 to 15 sec

  8. Single-mode saturation of the bump-on-tail instability

    International Nuclear Information System (INIS)

    Simon, A.; Rosenbluth, M.N.

    1976-01-01

    A slightly unstable plasma with only one or a few linear modes unstable is considered. Nonlinear saturation at small amplitudes has been treated by time-asymptotic analysis which is a generalization of the methods of Bogolyubov and co-workers. In this paper the method is applied to instability in a collisionless plasma governed by the vlasov equation. The bump-on-tail instability is considered for a one-dimensional plasma

  9. Light curves for ''bump Cepheids'' computed with a dynamically zoned pulsation code

    International Nuclear Information System (INIS)

    Adams, T.F.; Castor, J.E.; Davis, C.G.

    1978-01-01

    The dynamically zoned pulsation code developed by Castor, Davis, and Davison has been used to recalculate the Goddard model and to calculate three other Cepheid models with the same period (9.8 days). This family of models shows how the bumps and other features of the light and velocity curves change as the mass is varied at constant period. This study, with a code that is capable of producing reliable light curves, shows again that the light and velocity curves for 9.8-day Cepheid models with standard homogeneous compositions do not show bumps like those that are observed unless the mass is significantly lower than the ''evolutionary mass.'' The light and velocity curves for the Goddard model presented here are similar to those computed independently by Fischel, Sparks, and Karp. They should be useful as standards for future investigators

  10. Bump evolution driven by the x-ray ablation Richtmyer-Meshkov effect in plastic inertial confinement fusion Ablators

    Directory of Open Access Journals (Sweden)

    Loomis Eric

    2013-11-01

    Full Text Available Growth of hydrodynamic instabilities at the interfaces of inertial confinement fusion capsules (ICF due to ablator and fuel non-uniformities are a primary concern for the ICF program. Recently, observed jetting and parasitic mix into the fuel were attributed to isolated defects on the outer surface of the capsule. Strategies for mitigation of these defects exist, however, they require reduced uncertainties in Equation of State (EOS models prior to invoking them. In light of this, we have begun a campaign to measure the growth of isolated defects (bumps due to x-ray ablation Richtmyer-Meshkov in plastic ablators to validate these models. Experiments used hohlraums with radiation temperatures near 70 eV driven by 15 beams from the Omega laser (Laboratory for Laser Energetics, University of Rochester, NY, which sent a ∼1.25Mbar shock into a planar CH target placed over one laser entrance hole. Targets consisted of 2-D arrays of quasi-gaussian bumps (10 microns tall, 34 microns FWHM deposited on the surface facing into the hohlraum. On-axis radiography with a saran (Cl Heα − 2.76keV backlighter was used to measure bump evolution prior to shock breakout. Shock speed measurements were also performed to determine target conditions. Simulations using the LEOS 5310 and SESAME 7592 models required the simulated laser power be turned down to 80 and 88%, respectively to match observed shock speeds. Both LEOS 5310 and SESAME 7592 simulations agreed with measured bump areal densities out to 6 ns where ablative RM oscillations were observed in previous laser-driven experiments, but did not occur in the x-ray driven case. The QEOS model, conversely, over predicted shock speeds and under predicted areal density in the bump.

  11. Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblasts

    International Nuclear Information System (INIS)

    Kim, Sang-in; Pfeifer, Gerd P.; Besaratinia, Ahmad

    2007-01-01

    Sunlight ultraviolet A (UVA) irradiation has been implicated in the etiology of human skin cancer. A genotoxic mode of action for UVA radiation has been suggested that involves photosensitization reactions giving rise to promutagenic DNA lesions. We investigated the mutagenicity of UVA in the lacI transgene in Big Blue mouse embryonic fibroblasts. UVA irradiation of these cells at a physiologically relevant dose of 18 J/cm 2 caused a 2.8-fold increase in the lacI mutant frequency relative to control, i.e., 12.12 ± 1.84 versus 4.39 ± 1.99 x 10 -5 (mean ± S.D.). DNA sequencing analysis showed that of 100 UVA-induced mutant plaques and 54 spontaneously arisen control plaques, 97 and 51, respectively, contained a minimum of one mutation along the lacI transgene. The vast majority of both induced- and spontaneous mutations were single base substitutions, although less frequently, there were also single and multiple base deletions and insertions, and tandem base substitutions. Detailed mutation spectrometry analysis revealed that G:C → T:A transversions, the signature mutations of oxidative DNA damage, were significantly induced by UVA irradiation (P -5 ; P < 0.00001). These findings are in complete agreement with those previously observed in the cII transgene of the same model system, and reaffirm the notion that intracellular photosensitization reactions causing promutagenic oxidative DNA damage are involved in UVA genotoxicity

  12. Ship Sensor Observations for Investigating the Charleston Bump 2003 - Office of Ocean Exploration

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hourly measurements made by selected ship sensors on the R/V Seward Johnson during the "Investigating the Charleston Bump 2003" expedition sponsored by the National...

  13. The reminiscence bump without memories: The distribution of imagined word-cued and important autobiographical memories in a hypothetical 70-year-old

    DEFF Research Database (Denmark)

    Koppel, Jonathan; Berntsen, Dorthe

    2016-01-01

    The reminiscence bump is the disproportionate number of autobiographical memories dating from adolescence and early adulthood. It has often been ascribed to a consolidation of the mature self in the period covered by the bump. Here we stripped away factors relating to the characteristics of autob...

  14. Design and Experimental Development of a Pneumatic Stiffness Adjustable Foot System for Biped Robots Adaptable to Bumps on the Ground

    Directory of Open Access Journals (Sweden)

    Xizhe Zang

    2017-09-01

    Full Text Available Walking on rough terrains still remains a challenge that needs to be addressed for biped robots because the unevenness on the ground can easily disrupt the walking stability. This paper proposes a novel foot system with passively adjustable stiffness for biped robots which is adaptable to small-sized bumps on the ground. The robotic foot is developed by attaching eight pneumatic variable stiffness units to the sole separately and symmetrically. Each variable stiffness unit mainly consists of a pneumatic bladder and a mechanical reversing valve. When walking on rough ground, the pneumatic bladders in contact with bumps are compressed, and the corresponding reversing valves are triggered to expel out the air, enabling the pneumatic bladders to adapt to the bumps with low stiffness; while the other pneumatic bladders remain rigid and maintain stable contact with the ground, providing support to the biped robot. The performances of the proposed foot system, including the variable stiffness mechanism, the adaptability on the bumps of different heights, and the application on a biped robot prototype are demonstrated by various experiments.

  15. Ultraviolet photometry from the orbiting astronomical observatory. XX. The ultraviolet extinction bump

    International Nuclear Information System (INIS)

    Savage, B.D.

    1975-01-01

    Interstellar extinction curves over the wavelength region 1800--3600 A are presented for 36 stars. The stars have E (B-V) in the range 0.03 to 0.55, and are mostly confined to the brighter OB associations distributed along the plane of the Galaxy. Every extinction curve exhibits a broad extinction bump peaking near 2175 A (4.6 μ -1 ). The position of the peak and the profile of the feature appear remarkably constant among the sample of stars. With only a few exceptions, E (lambda)-3320, a measure of the strength of the feature, correlates very well with E (B-V), implying that the bump has an interstellar rather than a circumstellar origin. The observation that the bump position and shape are constant, or very nearly constant, places severe restrictions on the grain geometrical parameters if the feature is to be explained by classical scattering theory employing bulk optical constants. In fact, the restrictions are so severe that an alternate explanation seems to be required unless the dust grains that exist in widely separated regions of space and under very different physical conditions have nearly identical size and shape distributions. Three extinction curves that extend to 1100 A are also presented. These curves show the same general extinction characteristics reported earlier. The curve for 22 Sco provides another example of a star that is []physically associated with nebulosity and that also has abnormally low far-ultraviolet extinction. We have searched the extinction curves for fine structure such as abrupt slope changes or new diffuse interstellar features. Unfortunately, there is no convincing evidence for such structure over the interval 1800--3600 A. (auth)

  16. Sequence analysis of laci mutations obtained from lung cells of radon-exposed big blue trademark transgenic mice

    International Nuclear Information System (INIS)

    Layton, A.D.; Cross, F.T.; Steigler, G.L.; Stillwell, L.S.; Jostes, R.F.; Lutze, L.H.

    1994-01-01

    We have exposed Big Blue trademark transgenic mice by inhalation to 320, 640 and 960 Working Level Months (WLM) of radon progeny. Mice were sacrificed after 3, 6 and 9 days; the time periods required to obtain the exposures. Control mice were also sacrificed at each time interval. In each case all tissues were excised, flash frozen in liquid nitrogen, and stored at -80 degrees C for further analysis. Twelve lacI mutations have been isolated from the lung tissue of a mouse from the 960-WLM exposure group; the lacI genes from these mutants have been sequenced. Sequence data indicate that three of the mutants have a C;G deletion at BP 978 and are possibly clonal in origin. Two mutants have multiple events within the gene: one has a an A:T to C:G transversion and a C:G insertion separated by 291 BPs; the second has a G:C to A:T transition as well as an A:T deletion followed by 6 base pairs downstream by a T:A insertion. Other mutations include a single G:C to A:T transition, a two base pair deletion, and a C:G to T:A transition. Mutant plaques are being evaluated from individual mice at other dose levels. Time course experiments are also planned. These studies will help define the molecular fine structure of mutations induced by high-LET radiation exposure

  17. Indium-bump-free antimonide superlattice membrane detectors on silicon substrates

    Energy Technology Data Exchange (ETDEWEB)

    Zamiri, M., E-mail: mzamiri@chtm.unm.edu, E-mail: skrishna@chtm.unm.edu; Klein, B.; Schuler-Sandy, T.; Dahiya, V.; Cavallo, F. [Center for High Technology Materials, Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, New Mexico 87106 (United States); Myers, S. [SKINfrared, LLC, Lobo Venture Lab, 801 University Blvd., Suite 10, Albuquerque, New Mexico 87106 (United States); Krishna, S., E-mail: mzamiri@chtm.unm.edu, E-mail: skrishna@chtm.unm.edu [Center for High Technology Materials, Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, New Mexico 87106 (United States); SKINfrared, LLC, Lobo Venture Lab, 801 University Blvd., Suite 10, Albuquerque, New Mexico 87106 (United States)

    2016-02-29

    We present an approach to realize antimonide superlattices on silicon substrates without using conventional Indium-bump hybridization. In this approach, PIN superlattices are grown on top of a 60 nm Al{sub 0.6}Ga{sub 0.4}Sb sacrificial layer on a GaSb host substrate. Following the growth, the individual pixels are transferred using our epitaxial-lift off technique, which consists of a wet-etch to undercut the pixels followed by a dry-stamp process to transfer the pixels to a silicon substrate prepared with a gold layer. Structural and optical characterization of the transferred pixels was done using an optical microscope, scanning electron microscopy, and photoluminescence. The interface between the transferred pixels and the new substrate was abrupt, and no significant degradation in the optical quality was observed. An Indium-bump-free membrane detector was then fabricated using this approach. Spectral response measurements provided a 100% cut-off wavelength of 4.3 μm at 77 K. The performance of the membrane detector was compared to a control detector on the as-grown substrate. The membrane detector was limited by surface leakage current. The proposed approach could pave the way for wafer-level integration of photonic detectors on silicon substrates, which could dramatically reduce the cost of these detectors.

  18. Ultra-fast Movies Resolve Ultra-short Pulse Laser Ablation and Bump Formation on Thin Molybdenum Films

    Science.gov (United States)

    Domke, Matthias; Rapp, Stephan; Huber, Heinz

    For the monolithic serial interconnection of CIS thin film solar cells, 470 nm molybdenum films on glass substrates must be separated galvanically. The single pulse ablation with a 660 fs laser at a wavelength of 1053 nm is investigated in a fluence regime from 0.5 to 5.0 J/cm2. At fluences above 2.0 J/cm2 bump and jet formation can be observed that could be used for creating microstructures. For the investigation of the underlying mechanisms of the laser ablation process itself as well as of the bump or jet formation, pump probe microscopy is utilized to resolve the transient ablation behavior.

  19. Putting Together a Blue Sky: Laying the Foundation for Staff Evaluation

    Science.gov (United States)

    Searcy, Jeny

    2012-01-01

    Evaluation time can be like putting together a 5,000-piece jigsaw puzzle that is all sky--what, exactly, is the point? When all is said and done, one ends up with a big blue blob--nothing to show for all the effort. However, it doesn't have to be that way. Performance reviews can and should be an effective means of communication for both parties…

  20. Effects of long-term use by big game and livestock in the Blue Mountains forest ecosystems.

    Science.gov (United States)

    Larry L. Irwin; John G. Cook; Robert A. Riggs; Jon M. Skovlin

    1994-01-01

    The effects on eastside forest ecosystems from long-term grazing by large mammals are assessed, because long-term herbivory can reduce or increase ecosystem productivity. The assessment emphasizes elk and cattle in the Blue Mountains of northeast Oregon and southeast Washington. Histories of populations of large mammals and their effects in the Blue Mountains are...

  1. High-order integral equation methods for problems of scattering by bumps and cavities on half-planes.

    Science.gov (United States)

    Pérez-Arancibia, Carlos; Bruno, Oscar P

    2014-08-01

    This paper presents high-order integral equation methods for the evaluation of electromagnetic wave scattering by dielectric bumps and dielectric cavities on perfectly conducting or dielectric half-planes. In detail, the algorithms introduced in this paper apply to eight classical scattering problems, namely, scattering by a dielectric bump on a perfectly conducting or a dielectric half-plane, and scattering by a filled, overfilled, or void dielectric cavity on a perfectly conducting or a dielectric half-plane. In all cases field representations based on single-layer potentials for appropriately chosen Green functions are used. The numerical far fields and near fields exhibit excellent convergence as discretizations are refined-even at and around points where singular fields and infinite currents exist.

  2. Big data analytics turning big data into big money

    CERN Document Server

    Ohlhorst, Frank J

    2012-01-01

    Unique insights to implement big data analytics and reap big returns to your bottom line Focusing on the business and financial value of big data analytics, respected technology journalist Frank J. Ohlhorst shares his insights on the newly emerging field of big data analytics in Big Data Analytics. This breakthrough book demonstrates the importance of analytics, defines the processes, highlights the tangible and intangible values and discusses how you can turn a business liability into actionable material that can be used to redefine markets, improve profits and identify new business opportuni

  3. Big Opportunities and Big Concerns of Big Data in Education

    Science.gov (United States)

    Wang, Yinying

    2016-01-01

    Against the backdrop of the ever-increasing influx of big data, this article examines the opportunities and concerns over big data in education. Specifically, this article first introduces big data, followed by delineating the potential opportunities of using big data in education in two areas: learning analytics and educational policy. Then, the…

  4. Constraints on pre-big-bang parameter space from CMBR anisotropies

    International Nuclear Information System (INIS)

    Bozza, V.; Gasperini, M.; Giovannini, M.; Veneziano, G.

    2003-01-01

    The so-called curvaton mechanism--a way to convert isocurvature perturbations into adiabatic ones--is investigated both analytically and numerically in a pre-big-bang scenario where the role of the curvaton is played by a sufficiently massive Kalb-Ramond axion of superstring theory. When combined with observations of CMBR anisotropies at large and moderate angular scales, the present analysis allows us to constrain quite considerably the parameter space of the model: in particular, the initial displacement of the axion from the minimum of its potential and the rate of evolution of the compactification volume during pre-big-bang inflation. The combination of theoretical and experimental constraints favors a slightly blue spectrum of scalar perturbations, and/or a value of the string scale in the vicinity of the SUSY GUT scale

  5. Constraints on pre-big bang parameter space from CMBR anisotropies

    CERN Document Server

    Bozza, Valerio; Giovannini, Massimo; Veneziano, Gabriele

    2003-01-01

    The so-called curvaton mechanism --a way to convert isocurvature perturbations into adiabatic ones-- is investigated both analytically and numerically in a pre-big bang scenario where the role of the curvaton is played by a sufficiently massive Kalb--Ramond axion of superstring theory. When combined with observations of CMBR anisotropies at large and moderate angular scales, the present analysis allows us to constrain quite considerably the parameter space of the model: in particular, the initial displacement of the axion from the minimum of its potential and the rate of evolution of the compactification volume during pre-big bang inflation. The combination of theoretical and experimental constraints favours a slightly blue spectrum of scalar perturbations, and/or a value of the string scale in the vicinity of the SUSY-GUT scale.

  6. Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats

    Science.gov (United States)

    Mei, Nan; Guo, Lei; Liu, Ruqing; Fuscoe, James C; Chen, Tao

    2007-01-01

    Background Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plants grown in the western United States and is a prototype of genotoxic PAs. Riddelliine was used to investigate the genotoxic effects of PAs via analysis of gene expression in the target tissue of rats in this study. Previously we observed that the mutant frequency in the liver of rats gavaged with riddelliine was 3-fold higher than that in the control group. Molecular analysis of the mutants indicated that there was a statistically significant difference between the mutational spectra from riddelliine-treated and control rats. Results Riddelliine-induced gene expression profiles in livers of Big Blue transgenic rats were determined. The female rats were gavaged with riddelliine at a dose of 1 mg/kg body weight 5 days a week for 12 weeks. Rat whole genome microarray was used to perform genome-wide gene expression studies. When a cutoff value of a two-fold change and a P-value less than 0.01 were used as gene selection criteria, 919 genes were identified as differentially expressed in riddelliine-treated rats compared to the control animals. By analysis with the Ingenuity Pathway Analysis Network, we found that these significantly changed genes were mainly involved in cancer, cell death, tissue development, cellular movement, tissue morphology, cell-to-cell signaling and interaction, and cellular growth and proliferation. We further analyzed the genes involved in metabolism, injury of endothelial cells, liver abnormalities, and cancer development in detail. Conclusion The alterations in gene expression were directly related to the pathological outcomes reported previously. These results provided further insight into the mechanisms involved in toxicity and carcinogenesis after exposure to riddelliine, and permitted us to investigate the interaction of gene products inside the signaling networks

  7. Big Bear Exploration Ltd. 1998 annual report

    International Nuclear Information System (INIS)

    1999-01-01

    During the first quarter of 1998 Big Bear completed a purchase of additional assets in the Rainbow Lake area of Alberta in which light oil purchase was financed with new equity and bank debt. The business plan was to immediately exploit these light oil assets, the result of which would be increased reserves, production and cash flow. Although drilling results in the first quarter on the Rainbow Lake properties was mixed, oil prices started to free fall and drilling costs were much higher than expected. As a result, the company completed a reduced program which resulted in less incremental loss and cash flow than it budgeted for. On April 29, 1998, Big Bear entered into agreement with Belco Oil and Gas Corp. and Moan Investments Ltd. for the issuance of convertible preferred shares at a gross value of $15,750,000, which shares were eventually converted at 70 cents per share to common equity. As a result of the continued plunge in oil prices, the lending value of the company's assets continued to fall, requiring it to take action in order to meet its financial commitments. Late in the third quarter Big Bear issued equity for proceeds of $11,032,000 which further reduced the company's debt. Although the company has been extremely active in identifying and pursuing acquisition opportunities, it became evident that Belco Oil and Gas Corp. and Big Bear did nor share common criteria for acquisitions, which resulted in the restructuring of their relationship in the fourth quarter. With the future of oil prices in question, Big Bear decided that it would change its focus to that of natural gas and would refocus ts efforts to acquire natural gas assets to fuel its growth. The purchase of Blue Range put Big Bear in a difficult position in terms of the latter's growth. In summary, what started as a difficult year ended in disappointment

  8. Bumping structure of initial energy density distributions and peculiarities of pion spectra in A + A collisions

    International Nuclear Information System (INIS)

    Borysova, M.S.

    2012-01-01

    The effect of a fluctuating bumping structure of the initial conditions on spectra and the collective evolution of matter created in heavy-ion collisions in the frameworks of the Hydro-Kinetic Model is investigated. As motivated by the glasma-flux-tube scenario, the initial conditions are modeled by the set of four high energy-density tube-like fluctuations with longitudinally homogeneous structure within some space-rapidity region in a boost-invariant 2D geometry. It was found that the presence of transversally bumping tube-like fluctuations in initial conditions strongly affects the hydrodynamic evolution and leads to emergence of conspicuous structures in the calculated pion spectra. It was observed that the 4 tube initial configuration generates a four-peak structure in the final azimuthal distributions of one-particle spectra.

  9. Multipole error analysis using local 3-bump orbit data in Fermilab Recycler

    International Nuclear Information System (INIS)

    Yang, M.J.; Xiao, M.

    2005-01-01

    The magnetic harmonic errors of the Fermilab Recycler ring were examined using circulating beam data taken with closed local orbit bumps. Data was first parsed into harmonic orbits of first, second, and third order. Each of which was analyzed for sources of magnetic errors of corresponding order. This study was made possible only with the incredible resolution of a new BPM system that was commissioned after June of 2003

  10. Sequence analysis of LACI mutations obtained from lung cells of control and radon-exposed Big Blue trademark transgenic mice

    International Nuclear Information System (INIS)

    Jostes, R.F.; Cross, F.T.; Stillwell, L.

    1995-01-01

    We have exposed Stratagene Big Blue trademark transgenic mice by inhalation to 310, 640 and 960 Working Level Months (WLM) of radon progency. Twelve LacI mutations have been isolated from the lung tissue of a mouse from the 960-WLM group and the LacI gene sequenced. Mutations are scored only if they occur unambiguously in both strands of the mutant gene; the entire gene is evaluated. In addition, sixteen LacI mutations were isolated from the lung tissue of a mouse from the 640-WLM group; seven have been completely sequenced. Nine LacI mutations from the lung tissue of unirradiated control mice have been sequenced. Sequence data from the unirradiated mice are similar to that found in lung tissue at Stratagene; predominately G:C to A:T transitions in the protein associated region. The mutation spectrum from radon-irradiated mice is markedly different from that obtained with the control, unirradiated mice. Small deletions and insertions compromise 53% of the mutations in the irradiated mice. No multiple events have been noted in the spontaneous mutations; six of the mutations obtained from radon-irradiated mice (26%) have multiple events within the gene. In some, deletions, insertions are base changes occur together. The mutational events in the irradiated mice are approximately equally distributed throughout the gene. The breakpoint rejoining regions of large deletions obtained from the radon-irradiated mice are being studied at the University of California, San Francisco

  11. The reminiscence bump without memories: The distribution of imagined word-cued and important autobiographical memories in a hypothetical 70-year-old.

    Science.gov (United States)

    Koppel, Jonathan; Berntsen, Dorthe

    2016-08-01

    The reminiscence bump is the disproportionate number of autobiographical memories dating from adolescence and early adulthood. It has often been ascribed to a consolidation of the mature self in the period covered by the bump. Here we stripped away factors relating to the characteristics of autobiographical memories per se, most notably factors that aid in their encoding or retention, by asking students to generate imagined word-cued and imagined 'most important' autobiographical memories of a hypothetical, prototypical 70-year-old of their own culture and gender. We compared the distribution of these fictional memories with the distributions of actual word-cued and most important autobiographical memories in a sample of 61-70-year-olds. We found a striking similarity between the temporal distributions of the imagined memories and the actual memories. These results suggest that the reminiscence bump is largely driven by constructive, schematic factors at retrieval, thereby challenging most existing theoretical accounts. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. A new interpretation of luminous blue stars

    International Nuclear Information System (INIS)

    Stothers, R.

    1976-01-01

    A major revision of current theoretical ideas about the brightest blue stars must be made if Carson's new radiative opacities are adopted in stellar models. Unlike earlier opacities, the new opacities exhibit a large ''bump'' due to CNO ionization, which leads to very strong central condensation, convective instability, and pulsational instability in hot, diffuse stellar envelopes (typically those in which L/M>10 3 solar units). Despite a number of theoretical uncertainties, the new picture of the structure of very luminous stars is reasonably successful in accounting for a variety of previously unexplained observations. Thus, the new stellar models for the phase of core hydrogen burning predict large radii and rather cool effective temperatures (which are yet to be observationally confirmed) for O stars, and a spreading out of the main-sequence band in the H-R diagram toward luminous cool supergiants for masses higher than approx.20 M/sub sun/, beginning at M/sub v/=-4.5 and Sp=B1. They also predict slower surface rotations for O stars compared with B stars; and, in binary systems, slower apsidal motions, closer rotational-revolutional synchronism, and smaller orbital eccentricities. In massive X-ray binary systems, circular orbits and supergiant-like visual companions are expected to be quite common. Radial pulsations of the models have been calculated by employing linearized nonadiabatic pulsation theory. Long-period variability is predicted to exist for massive blue supergiants of luminosity class Ia. The new models for helium stars predict large radii and rather cool effective temperatures for Wolf-Rayet stars, as well as multimodal pulsational instability and, possibly, surface turbulence for these stars. Ultrashort-period variability, observed in many classes of hot luminous stars, may be due, in part, to high radial overtone pulsations (or, possibly, to nonradial pulsation or convective modes)

  13. Forming mechanism and avoiding measures of blue-ring on electronic beam welding sample after water corrosion

    International Nuclear Information System (INIS)

    Ren Defang; Luo Xiandian; Tong Shenxiu; Guo Xulin; Peng Haiqing

    2001-01-01

    After water corrosion in compliance with ASTM G2, the blue ring appears on the nuclear fuel rod samples of AFA 2G welded by using a Big Chamber Electron Beam Welder made in Russia. The characteristics, appearance, chemical composition, microstructure of b lue ring a nd some condition test are described. The mechanism of forming blue ring may be depicted as following: welding metal vapor and the splash produced by secondary and scatter electrons on metal clamp and gun body deposit in the area between HAZ and substrate because of the water cooling down effects on the clamp; these deposits, after water corrosion, appears as blue ring on the fuel rod surface. Avoiding measure is that the side of the clamp closing to weld seal is chamfered, while making the welding chamber cleaner

  14. How Big Are "Martin's Big Words"? Thinking Big about the Future.

    Science.gov (United States)

    Gardner, Traci

    "Martin's Big Words: The Life of Dr. Martin Luther King, Jr." tells of King's childhood determination to use "big words" through biographical information and quotations. In this lesson, students in grades 3 to 5 explore information on Dr. King to think about his "big" words, then they write about their own…

  15. Improved Switching Characteristics of Fast Power MOSFETs Applying Solder Bump Technology

    Directory of Open Access Journals (Sweden)

    Sibylle Dieckerhoff

    2008-01-01

    Full Text Available The impact of a reduced package stray inductance on the switching performance of fast power MOSFETs is discussed applying advanced 3D packaging technologies. Starting from an overview over new packaging approaches, a solder bump technology using a flexible PI substrate is exemplarily chosen for the evaluation. Measurement techniques to determine the stray inductance are discussed and compared with a numerical solution based on the PEEC method. Experimental results show the improvement of the voltage utilization while there is only a slight impact on total switching losses.

  16. Down to earth with a bump

    CERN Multimedia

    Adam, D

    2001-01-01

    In 2001 both the ISS and the LHC project ran into serious financial difficulties. This could have serious repercussions for other 'big science' projects trying to attract funding from already nervous politicians (1 page).

  17. CO2laser-induced bump formation and growth on polystyrene for multi-depth soft lithography molds

    KAUST Repository

    Li, Huawei; Fan, Yiqiang; Conchouso Gonzalez, David; Foulds, Ian G.

    2012-01-01

    result from the net volume gain of the laser heat-affected zone on the PS rather than from a deposition process, and the expansion of the heat-affected zone on PS was verified by measuring the hardness change using nanoindentation. The bumps have a much

  18. Miniaturization of Micro-Solder Bumps and Effect of IMC on Stress Distribution

    Science.gov (United States)

    Choudhury, Soud Farhan; Ladani, Leila

    2016-07-01

    As the joints become smaller in more advanced packages and devices, intermetallic (IMCs) volume ratio increases, which significantly impacts the overall mechanical behavior of joints. The existence of only a few grains of Sn (Tin) and IMC materials results in anisotropic elastic and plastic behavior which is not detectable using conventional finite element (FE) simulation with average properties for polycrystalline material. In this study, crystal plasticity finite element (CPFE) simulation is used to model the whole joint including copper, Sn solder and Cu6Sn5 IMC material. Experimental lap-shear test results for solder joints from the literature were used to validate the models. A comparative analysis between traditional FE, CPFE and experiments was conducted. The CPFE model was able to correlate the experiments more closely compared to traditional FE analysis because of its ability to capture micro-mechanical anisotropic behavior. Further analysis was conducted to evaluate the effect of IMC thickness on stress distribution in micro-bumps using a systematic numerical experiment with IMC thickness ranging from 0% to 80%. The analysis was conducted on micro-bumps with single crystal Sn and bicrystal Sn. The overall stress distribution and shear deformation changes as the IMC thickness increases. The model with higher IMC thickness shows a stiffer shear response, and provides a higher shear yield strength.

  19. IS THE LATE NEAR-INFRARED BUMP IN SHORT-HARD GRB 130603B DUE TO THE LI-PACZYNSKI KILONOVA?

    International Nuclear Information System (INIS)

    Jin, Zhi-Ping; Fan, Yi-Zhong; Wei, Da-Ming; Xu, Dong; Wu, Xue-Feng

    2013-01-01

    Short-hard gamma-ray bursts (GRBs) are widely believed to be produced by the merger of two binary compact objects, specifically by two neutron stars or by a neutron star orbiting a black hole. According to the Li-Paczynski kilonova model, the merger would launch sub-relativistic ejecta and a near-infrared/optical transient would then occur, lasting up to days, which is powered by the radioactive decay of heavy elements synthesized in the ejecta. The detection of a late bump using the Hubble Space Telescope (HST) in the near-infrared afterglow light curve of the short-hard GRB 130603B is indeed consistent with such a model. However, as shown in this Letter, the limited HST near-infrared light curve behavior can also be interpreted as the synchrotron radiation of the external shock driven by a wide mildly relativistic outflow. In such a scenario, the radio emission is expected to peak with a flux of ∼100 μJy, which is detectable for current radio arrays. Hence, the radio afterglow data can provide complementary evidence on the nature of the bump in GRB 130603B. It is worth noting that good spectroscopy during the bump phase in short-hard bursts can test the validity of either model above, analogous to spectroscopy of broad-lined Type Ic supernova in long-soft GRBs

  20. USING THE 1.6 μm BUMP TO STUDY REST-FRAME NEAR-INFRARED-SELECTED GALAXIES AT REDSHIFT 2

    International Nuclear Information System (INIS)

    Sorba, Robert; Sawicki, Marcin

    2010-01-01

    We explore the feasibility and limitations of using the 1.6 μm bump as a photometric redshift indicator and selection technique, and use it to study the rest-frame H-band galaxy luminosity and stellar mass functions (SMFs) at redshift z ∼ 2. We use publicly available Spitzer/IRAC images in the GOODS fields and find that color selection in the IRAC bandpasses alone is comparable in completeness and contamination to BzK selection. We find that the shape of the 1.6 μm bump is robust, and photometric redshifts are not greatly affected by choice of model parameters. Comparison with spectroscopic redshifts shows photometric redshifts to be reliable. We create a rest-frame NIR-selected catalog of galaxies at z ∼ 2 and construct a galaxy SMF. Comparisons with other SMFs at approximately the same redshift but determined using shorter wavelengths show good agreement. This agreement suggests that selection at bluer wavelengths does not miss a significant amount of stellar mass in passive galaxies. Comparison with SMFs at other redshifts shows evidence for the downsizing scenario of galaxy evolution. We conclude by pointing out the potential for using the 1.6 μm bump technique to select high-redshift galaxies with the JWST, whose λ>0.6 μm coverage will not be well suited to selecting galaxies using techniques that require imaging at shorter wavelengths.

  1. Non-thermal AGN models

    Energy Technology Data Exchange (ETDEWEB)

    Band, D.L.

    1986-12-01

    The infrared, optical and x-ray continua from radio quiet active galactic nuclei (AGN) are explained by a compact non-thermal source surrounding a thermal ultraviolet emitter, presumably the accretion disk around a supermassive black hole. The ultraviolet source is observed as the ''big blue bump.'' The flat (..cap alpha.. approx. = .7) hard x-ray spectrum results from the scattering of thermal ultraviolet photons by the flat, low energy end of an electron distribution ''broken'' by Compton losses; the infrared through soft x-ray continuum is the synchrotron radiation of the steep, high energy end of the electron distribution. Quantitative fits to specific AGN result in models which satisfy the variability constraints but require electron (re)acceleration throughout the source. 11 refs., 1 fig.

  2. Big Data, Big Problems: A Healthcare Perspective.

    Science.gov (United States)

    Househ, Mowafa S; Aldosari, Bakheet; Alanazi, Abdullah; Kushniruk, Andre W; Borycki, Elizabeth M

    2017-01-01

    Much has been written on the benefits of big data for healthcare such as improving patient outcomes, public health surveillance, and healthcare policy decisions. Over the past five years, Big Data, and the data sciences field in general, has been hyped as the "Holy Grail" for the healthcare industry promising a more efficient healthcare system with the promise of improved healthcare outcomes. However, more recently, healthcare researchers are exposing the potential and harmful effects Big Data can have on patient care associating it with increased medical costs, patient mortality, and misguided decision making by clinicians and healthcare policy makers. In this paper, we review the current Big Data trends with a specific focus on the inadvertent negative impacts that Big Data could have on healthcare, in general, and specifically, as it relates to patient and clinical care. Our study results show that although Big Data is built up to be as a the "Holy Grail" for healthcare, small data techniques using traditional statistical methods are, in many cases, more accurate and can lead to more improved healthcare outcomes than Big Data methods. In sum, Big Data for healthcare may cause more problems for the healthcare industry than solutions, and in short, when it comes to the use of data in healthcare, "size isn't everything."

  3. Big Surveys, Big Data Centres

    Science.gov (United States)

    Schade, D.

    2016-06-01

    Well-designed astronomical surveys are powerful and have consistently been keystones of scientific progress. The Byurakan Surveys using a Schmidt telescope with an objective prism produced a list of about 3000 UV-excess Markarian galaxies but these objects have stimulated an enormous amount of further study and appear in over 16,000 publications. The CFHT Legacy Surveys used a wide-field imager to cover thousands of square degrees and those surveys are mentioned in over 1100 publications since 2002. Both ground and space-based astronomy have been increasing their investments in survey work. Survey instrumentation strives toward fair samples and large sky coverage and therefore strives to produce massive datasets. Thus we are faced with the "big data" problem in astronomy. Survey datasets require specialized approaches to data management. Big data places additional challenging requirements for data management. If the term "big data" is defined as data collections that are too large to move then there are profound implications for the infrastructure that supports big data science. The current model of data centres is obsolete. In the era of big data the central problem is how to create architectures that effectively manage the relationship between data collections, networks, processing capabilities, and software, given the science requirements of the projects that need to be executed. A stand alone data silo cannot support big data science. I'll describe the current efforts of the Canadian community to deal with this situation and our successes and failures. I'll talk about how we are planning in the next decade to try to create a workable and adaptable solution to support big data science.

  4. Recht voor big data, big data voor recht

    NARCIS (Netherlands)

    Lafarre, Anne

    Big data is een niet meer weg te denken fenomeen in onze maatschappij. Het is de hype cycle voorbij en de eerste implementaties van big data-technieken worden uitgevoerd. Maar wat is nu precies big data? Wat houden de vijf V's in die vaak genoemd worden in relatie tot big data? Ter inleiding van

  5. Temporal distribution of autobiographical memory: uncovering the reminiscence bump in Japanese young and middle-aged adults

    NARCIS (Netherlands)

    Kawasaki, Y.; Janssen, S.M.J.; Inoue, T.

    2011-01-01

    The reminiscence bump is the effect that people recall more personal events from their teenage period than from adjacent lifetime periods. The effect is generally found in studies that divide the results of participants, who were at least 40 years old, into age bins of 10 years. In this study, the

  6. Effect of Joint Scale and Processing on the Fracture of Sn-3Ag-0.5Cu Solder Joints: Application to Micro-bumps in 3D Packages

    Science.gov (United States)

    Talebanpour, B.; Huang, Z.; Chen, Z.; Dutta, I.

    2016-01-01

    In 3-dimensional (3D) packages, a stack of dies is vertically connected to each other using through-silicon vias and very thin solder micro-bumps. The thinness of the micro-bumps results in joints with a very high volumetric proportion of intermetallic compounds (IMCs), rendering them much more brittle compared to conventional joints. Because of this, the reliability of micro-bumps, and the dependence thereof on the proportion of IMC in the joint, is of substantial concern. In this paper, the growth kinetics of IMCs in thin Sn-3Ag-0.5Cu joints attached to Cu substrates were analyzed, and empirical kinetic laws for the growth of Cu6Sn5 and Cu3Sn in thin joints were obtained. Modified compact mixed mode fracture mechanics samples, with adhesive solder joints between massive Cu substrates, having similar thickness and IMC content as actual micro-bumps, were produced. The effects of IMC proportion and strain rate on fracture toughness and mechanisms were investigated. It was found that the fracture toughness G C decreased with decreasing joint thickness ( h Joint). In addition, the fracture toughness decreased with increasing strain rate. Aging also promoted alternation of the crack path between the two joint-substrate interfaces, possibly proffering a mechanism to enhance fracture toughness.

  7. BigOP: Generating Comprehensive Big Data Workloads as a Benchmarking Framework

    OpenAIRE

    Zhu, Yuqing; Zhan, Jianfeng; Weng, Chuliang; Nambiar, Raghunath; Zhang, Jinchao; Chen, Xingzhen; Wang, Lei

    2014-01-01

    Big Data is considered proprietary asset of companies, organizations, and even nations. Turning big data into real treasure requires the support of big data systems. A variety of commercial and open source products have been unleashed for big data storage and processing. While big data users are facing the choice of which system best suits their needs, big data system developers are facing the question of how to evaluate their systems with regard to general big data processing needs. System b...

  8. How Big Is Too Big?

    Science.gov (United States)

    Cibes, Margaret; Greenwood, James

    2016-01-01

    Media Clips appears in every issue of Mathematics Teacher, offering readers contemporary, authentic applications of quantitative reasoning based on print or electronic media. This issue features "How Big is Too Big?" (Margaret Cibes and James Greenwood) in which students are asked to analyze the data and tables provided and answer a…

  9. NOAA TIFF Image - 50m Rugosity, Charleston Bump - Deep Coral Priority Areas - Whiting - (2001), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 50x50 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  10. NOAA TIFF Image - 50m Rugosity, Charleston Bump - Deep Coral Priority Areas - Whiting - (2000), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 50x50 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  11. Limit cycle behaviour of the bump-on-tail and ion-acoustic instability

    International Nuclear Information System (INIS)

    Janssen, P.A.E.M.; Rasmussen, J.J.

    1980-12-01

    The nonlinear dynamics of the bump-on-tail and current-driven ion-acoustic instability is considered. The eigenmodes have discrete k because of finite periodic boundary conditions. Increasing a critical parameter (the number density and the electron drift velocity respectively) above its neutral stable value by a small fractional amount Δ 2 , one mode becomes unstable. The nonlinear dynamics of the unstable mode is determined by means of the multiple time scale method. Usually, limit cycle behaviour is found. A short comparison with quasi-linear theory is given, and the results are compared with experiment. (Auth.)

  12. Nursing Needs Big Data and Big Data Needs Nursing.

    Science.gov (United States)

    Brennan, Patricia Flatley; Bakken, Suzanne

    2015-09-01

    Contemporary big data initiatives in health care will benefit from greater integration with nursing science and nursing practice; in turn, nursing science and nursing practice has much to gain from the data science initiatives. Big data arises secondary to scholarly inquiry (e.g., -omics) and everyday observations like cardiac flow sensors or Twitter feeds. Data science methods that are emerging ensure that these data be leveraged to improve patient care. Big data encompasses data that exceed human comprehension, that exist at a volume unmanageable by standard computer systems, that arrive at a velocity not under the control of the investigator and possess a level of imprecision not found in traditional inquiry. Data science methods are emerging to manage and gain insights from big data. The primary methods included investigation of emerging federal big data initiatives, and exploration of exemplars from nursing informatics research to benchmark where nursing is already poised to participate in the big data revolution. We provide observations and reflections on experiences in the emerging big data initiatives. Existing approaches to large data set analysis provide a necessary but not sufficient foundation for nursing to participate in the big data revolution. Nursing's Social Policy Statement guides a principled, ethical perspective on big data and data science. There are implications for basic and advanced practice clinical nurses in practice, for the nurse scientist who collaborates with data scientists, and for the nurse data scientist. Big data and data science has the potential to provide greater richness in understanding patient phenomena and in tailoring interventional strategies that are personalized to the patient. © 2015 Sigma Theta Tau International.

  13. BIG Data - BIG Gains? Understanding the Link Between Big Data Analytics and Innovation

    OpenAIRE

    Niebel, Thomas; Rasel, Fabienne; Viete, Steffen

    2017-01-01

    This paper analyzes the relationship between firms’ use of big data analytics and their innovative performance for product innovations. Since big data technologies provide new data information practices, they create new decision-making possibilities, which firms can use to realize innovations. Applying German firm-level data we find suggestive evidence that big data analytics matters for the likelihood of becoming a product innovator as well as the market success of the firms’ product innovat...

  14. Networking for big data

    CERN Document Server

    Yu, Shui; Misic, Jelena; Shen, Xuemin (Sherman)

    2015-01-01

    Networking for Big Data supplies an unprecedented look at cutting-edge research on the networking and communication aspects of Big Data. Starting with a comprehensive introduction to Big Data and its networking issues, it offers deep technical coverage of both theory and applications.The book is divided into four sections: introduction to Big Data, networking theory and design for Big Data, networking security for Big Data, and platforms and systems for Big Data applications. Focusing on key networking issues in Big Data, the book explains network design and implementation for Big Data. It exa

  15. Global fluctuation spectra in big-crunch-big-bang string vacua

    International Nuclear Information System (INIS)

    Craps, Ben; Ovrut, Burt A.

    2004-01-01

    We study big-crunch-big-bang cosmologies that correspond to exact world-sheet superconformal field theories of type II strings. The string theory spacetime contains a big crunch and a big bang cosmology, as well as additional 'whisker' asymptotic and intermediate regions. Within the context of free string theory, we compute, unambiguously, the scalar fluctuation spectrum in all regions of spacetime. Generically, the big crunch fluctuation spectrum is altered while passing through the bounce singularity. The change in the spectrum is characterized by a function Δ, which is momentum and time dependent. We compute Δ explicitly and demonstrate that it arises from the whisker regions. The whiskers are also shown to lead to 'entanglement' entropy in the big bang region. Finally, in the Milne orbifold limit of our superconformal vacua, we show that Δ→1 and, hence, the fluctuation spectrum is unaltered by the big-crunch-big-bang singularity. We comment on, but do not attempt to resolve, subtleties related to gravitational back reaction and light winding modes when interactions are taken into account

  16. Regeneration in United States Department of Agriculture Forest Service mixed conifer partial cuttings in the Blue Mountains of Oregon and Washington.

    Science.gov (United States)

    K.W. Seidel; S. Conrade. Head

    1983-01-01

    A survey in the Blue Mountains of north-eastern Oregon and southeastern Washington showed that, on the average, partial cuts in the grand fir/big huckleberry community were well stocked with a mixture of advance, natural post-harvest, and planted reproduction of a number of species. Partial cuts in the mixed conifer/pinegrass community had considerably fewer seedlings...

  17. NOAA TIFF Image - 50m Backscatter, Charleston Bump - Deep Coral Priority Areas - Nancy Foster - (2006), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the backscatter intensity of the Charleston Bump off of the South Atlantic Bight,...

  18. Big Argumentation?

    Directory of Open Access Journals (Sweden)

    Daniel Faltesek

    2013-08-01

    Full Text Available Big Data is nothing new. Public concern regarding the mass diffusion of data has appeared repeatedly with computing innovations, in the formation before Big Data it was most recently referred to as the information explosion. In this essay, I argue that the appeal of Big Data is not a function of computational power, but of a synergistic relationship between aesthetic order and a politics evacuated of a meaningful public deliberation. Understanding, and challenging, Big Data requires an attention to the aesthetics of data visualization and the ways in which those aesthetics would seem to depoliticize information. The conclusion proposes an alternative argumentative aesthetic as the appropriate response to the depoliticization posed by the popular imaginary of Big Data.

  19. NOAA TIFF Image - 50m Singlebeam Bathymetry, Charleston Bump - Deep Coral Priority Areas - Whiting - (2000), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 50x50 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  20. NOAA TIFF Image - 50m Multibeam Bathymetry, Charleston Bump - Deep Coral Priority Areas - Whiting - (2001), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 50x50 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  1. NOAA TIFF Image - 30m Rugosity, Charleston Bump - Deep Coral Priority Areas - Thomas Jefferson - (2007), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  2. NOAA TIFF Image - 50m Singlebeam Slope, Charleston Bump - Deep Coral Priority Areas - Whiting - (2000), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 50x50 meter cell size representing the slope of the Charleston Bump off of the South Atlantic Bight, derived from...

  3. NOAA TIFF Image - 30m Rugosity, Charleston Bump - Deep Coral Priority Areas - Nancy Foster - (2006), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the 2006 multibeam bathymetry of the Charleston Bump off of the South Atlantic Bight,...

  4. NOAA TIFF Image - 30m Slope, Charleston Bump - Deep Coral Priority Areas - Little Hales- (2003), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the slope (in degrees) of themultibeam bathymetry of the Charleston Bump off of the...

  5. NOAA TIFF Image - 30m Slope, Charleston Bump - Deep Coral Priority Areas - Nancy Foster - (2006), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the slope (in degrees) of the 2006 multibeam bathymetry of the Charleston Bump off of...

  6. Big data

    DEFF Research Database (Denmark)

    Madsen, Anders Koed; Flyverbom, Mikkel; Hilbert, Martin

    2016-01-01

    is to outline a research agenda that can be used to raise a broader set of sociological and practice-oriented questions about the increasing datafication of international relations and politics. First, it proposes a way of conceptualizing big data that is broad enough to open fruitful investigations......The claim that big data can revolutionize strategy and governance in the context of international relations is increasingly hard to ignore. Scholars of international political sociology have mainly discussed this development through the themes of security and surveillance. The aim of this paper...... into the emerging use of big data in these contexts. This conceptualization includes the identification of three moments contained in any big data practice. Second, it suggests a research agenda built around a set of subthemes that each deserve dedicated scrutiny when studying the interplay between big data...

  7. Cross-validation and Peeling Strategies for Survival Bump Hunting using Recursive Peeling Methods

    Science.gov (United States)

    Dazard, Jean-Eudes; Choe, Michael; LeBlanc, Michael; Rao, J. Sunil

    2015-01-01

    We introduce a framework to build a survival/risk bump hunting model with a censored time-to-event response. Our Survival Bump Hunting (SBH) method is based on a recursive peeling procedure that uses a specific survival peeling criterion derived from non/semi-parametric statistics such as the hazards-ratio, the log-rank test or the Nelson--Aalen estimator. To optimize the tuning parameter of the model and validate it, we introduce an objective function based on survival or prediction-error statistics, such as the log-rank test and the concordance error rate. We also describe two alternative cross-validation techniques adapted to the joint task of decision-rule making by recursive peeling and survival estimation. Numerical analyses show the importance of replicated cross-validation and the differences between criteria and techniques in both low and high-dimensional settings. Although several non-parametric survival models exist, none addresses the problem of directly identifying local extrema. We show how SBH efficiently estimates extreme survival/risk subgroups unlike other models. This provides an insight into the behavior of commonly used models and suggests alternatives to be adopted in practice. Finally, our SBH framework was applied to a clinical dataset. In it, we identified subsets of patients characterized by clinical and demographic covariates with a distinct extreme survival outcome, for which tailored medical interventions could be made. An R package PRIMsrc (Patient Rule Induction Method in Survival, Regression and Classification settings) is available on CRAN (Comprehensive R Archive Network) and GitHub. PMID:27034730

  8. Big data computing

    CERN Document Server

    Akerkar, Rajendra

    2013-01-01

    Due to market forces and technological evolution, Big Data computing is developing at an increasing rate. A wide variety of novel approaches and tools have emerged to tackle the challenges of Big Data, creating both more opportunities and more challenges for students and professionals in the field of data computation and analysis. Presenting a mix of industry cases and theory, Big Data Computing discusses the technical and practical issues related to Big Data in intelligent information management. Emphasizing the adoption and diffusion of Big Data tools and technologies in industry, the book i

  9. 'Blue bubble' technique: an ab interno approach for Descemet separation in deep anterior lamellar keratoplasty using trypan blue stained viscoelastic device.

    Science.gov (United States)

    Livny, Eitan; Bahar, Irit; Hammel, Naama; Nahum, Yoav

    2018-04-01

    In this study, we examined a novel variant of 'big-bubble' deep anterior lamellar keratoplasty using trypan-blue-stained viscoelastic device for the creation of a pre-descemetic bubble. Ten corneoscleral rims were mounted on an artificial anterior chamber (AC). The AC was filled with air through a limbal paracentesis. A Melles' triangulated spatula was inserted through the paracentesis, with its tip penetrating the AC, was then slightly retracted and pushed into the deep stroma above the roof of the paracentesis. A mixture of trypan blue and viscoelastic device (Healon, Abbott Medical Optics, Abbott Park, Illinois) was injected into this intra-stromal pocket using a 27-G cannula to create a pre-descemetic separation bubble. Bubble type and visualization of dyed viscoelastic device were noted. The method was later employed in three cases. In all 10 corneoscleral rims, the technique successfully created a visible pre-descemetic (type 1) bubble that could be expanded up to the predicted diameter of trephination. Subsequent trephination and the removal of corneal stroma were uneventful. In two out of four clinical cases, a type 1 bubble was created, while in two others, visco-dissection failed and dyed viscoelastic was seen in the AC. The presented technique holds promise of being a relatively easy to perform, predictable and well-controlled alternative for achieving a type 1 bubble during deep anterior lamellar keratoplasty surgery. The trypan-blue-stained viscoelastic device facilitates proper visualization and control of the separation bubble and assists in identifying the penetrance to the separation bubble prior to removal of the stromal cap. © 2017 Royal Australian and New Zealand College of Ophthalmologists.

  10. From big bang to big crunch and beyond

    International Nuclear Information System (INIS)

    Elitzur, Shmuel; Rabinovici, Eliezer; Giveon, Amit; Kutasov, David

    2002-01-01

    We study a quotient Conformal Field Theory, which describes a 3+1 dimensional cosmological spacetime. Part of this spacetime is the Nappi-Witten (NW) universe, which starts at a 'big bang' singularity, expands and then contracts to a 'big crunch' singularity at a finite time. The gauged WZW model contains a number of copies of the NW spacetime, with each copy connected to the preceding one and to the next one at the respective big bang/big crunch singularities. The sequence of NW spacetimes is further connected at the singularities to a series of non-compact static regions with closed timelike curves. These regions contain boundaries, on which the observables of the theory live. This suggests a holographic interpretation of the physics. (author)

  11. BIG data - BIG gains? Empirical evidence on the link between big data analytics and innovation

    OpenAIRE

    Niebel, Thomas; Rasel, Fabienne; Viete, Steffen

    2017-01-01

    This paper analyzes the relationship between firms’ use of big data analytics and their innovative performance in terms of product innovations. Since big data technologies provide new data information practices, they create novel decision-making possibilities, which are widely believed to support firms’ innovation process. Applying German firm-level data within a knowledge production function framework we find suggestive evidence that big data analytics is a relevant determinant for the likel...

  12. Recent developments in MrBUMP: better search-model preparation, graphical interaction with search models, and solution improvement and assessment.

    Science.gov (United States)

    Keegan, Ronan M; McNicholas, Stuart J; Thomas, Jens M H; Simpkin, Adam J; Simkovic, Felix; Uski, Ville; Ballard, Charles C; Winn, Martyn D; Wilson, Keith S; Rigden, Daniel J

    2018-03-01

    Increasing sophistication in molecular-replacement (MR) software and the rapid expansion of the PDB in recent years have allowed the technique to become the dominant method for determining the phases of a target structure in macromolecular X-ray crystallography. In addition, improvements in bioinformatic techniques for finding suitable homologous structures for use as MR search models, combined with developments in refinement and model-building techniques, have pushed the applicability of MR to lower sequence identities and made weak MR solutions more amenable to refinement and improvement. MrBUMP is a CCP4 pipeline which automates all stages of the MR procedure. Its scope covers everything from the sourcing and preparation of suitable search models right through to rebuilding of the positioned search model. Recent improvements to the pipeline include the adoption of more sensitive bioinformatic tools for sourcing search models, enhanced model-preparation techniques including better ensembling of homologues, and the use of phase improvement and model building on the resulting solution. The pipeline has also been deployed as an online service through CCP4 online, which allows its users to exploit large bioinformatic databases and coarse-grained parallelism to speed up the determination of a possible solution. Finally, the molecular-graphics application CCP4mg has been combined with MrBUMP to provide an interactive visual aid to the user during the process of selecting and manipulating search models for use in MR. Here, these developments in MrBUMP are described with a case study to explore how some of the enhancements to the pipeline and to CCP4mg can help to solve a difficult case.

  13. NOAA TIFF Image - 50m Multibeam Bathymetry, Charleston Bump - Deep Coral Priority Areas - Little Hales - (2003), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  14. NOAA TIFF Image - 30m Multibeam Bathymetry, Charleston Bump - Deep Coral Priority Areas - Nancy Foster - (2006), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  15. NOAA TIFF Image - 30m Multibeam Bathymetry, Charleston Bump - Deep Coral Priority Areas - Thomas Jefferson - (2007), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  16. Expanding Medicaid Access without Expanding Medicaid: Why Did Some Nonexpansion States Continue the Primary Care Fee Bump?

    Science.gov (United States)

    Wilk, Adam S; Evans, Leigh C; Jones, David K

    2018-02-01

    Six states that have rejected the Patient Protection and Affordable Care Act's (ACA) Medicaid expansion nonetheless extended the primary care "fee bump," by which the federal government increased Medicaid fees for primary care services up to 100 percent of Medicare fees during 2013-14. We conducted semistructured interviews with leaders in five of these states, as well as in three comparison states, to examine why they would continue a provision of the ACA that moderately expands access at significant state expense while rejecting the expansion and its large federal match, focusing on relevant economic, political, and procedural factors. We found that fee bump extension proposals were more successful where they were dissociated from major national policy debates, actionable with the input of relatively few stakeholder entities, and well aligned with preexisting policy-making structures and decision trends. Republican proposals to cap or reduce federal funding for Medicaid, if enacted, would compel states to contain program costs. In this context, states' established decision-making processes for updating Medicaid fee schedules, which we elucidate in this study, may shape the future of the Medicaid program. Copyright © 2018 by Duke University Press 2018.

  17. Transonic buffet control research with two types of shock control bump based on RAE2822 airfoil

    Directory of Open Access Journals (Sweden)

    Yun TIAN

    2017-10-01

    Full Text Available Current research shows that the traditional shock control bump (SCB can weaken the intensity of shock and better the transonic buffet performance. The author finds that when SCB is placed downstream of the shock, it can decrease the adverse pressure gradient. This may prevent the shock foot separation bubble to merge with the trailing edge separation and finally improve the buffet performance. Based on RAE2822 airfoil, two types of SCB are designed according to the two different mechanisms. By using Reynolds-averaged Navier-Stokes (RANS and unsteady Reynolds-averaged Navier-Stokes (URANS methods to analyze the properties of RAE2822 airfoil with and without SCB, the results show that the downstream SCB can better the buffet performance under a wide range of freestream Mach number and the steady aerodynamics characteristic is similar to that of RAE2822 airfoil. The traditional SCB can only weaken the intensity of the shock under the design condition. Under the off-design conditions, the SCB does not do much to or even worsen the buffet performance. Indeed, the use of backward bump can flatten the leeward side of the airfoil, and this is similar to the mechanism that supercritical airfoil can weaken the recompression of shock wave.

  18. Self-similar bumps and wiggles: Isolating the evolution of the BAO peak with power-law initial conditions

    International Nuclear Information System (INIS)

    Orban, Chris; Weinberg, David H.

    2011-01-01

    Motivated by cosmological surveys that demand accurate theoretical modeling of the baryon acoustic oscillation (BAO) feature in galaxy clustering, we analyze N-body simulations in which a BAO-like Gaussian bump modulates the linear theory correlation function ξ L (r)=(r 0 /r) n+3 of an underlying self-similar model with initial power spectrum P(k)=Ak n . These simulations test physical and analytic descriptions of BAO evolution far beyond the range of most studies, since we consider a range of underlying power spectra (n=-0.5, -1, -1.5) and evolve simulations to large effective correlation amplitudes (equivalent to σ 8 =4-12 for r bao =100h -1 Mpc). In all cases, nonlinear evolution flattens and broadens the BAO bump in ξ(r) while approximately preserving its area. This evolution resembles a diffusion process in which the bump width σ bao is the quadrature sum of the linear theory width and a length proportional to the rms relative displacement Σ pair (r bao ) of particle pairs separated by r bao . For n=-0.5 and n=-1, we find no detectable shift of the location of the BAO peak, but the peak in the n=-1.5 model shifts steadily to smaller scales, following r peak /r bao =1-1.08(r 0 /r bao ) 1.5 . The perturbation theory scheme of McDonald (2007) [P. McDonald, Phys. Rev. D 75, 043514 (2007).] and, to a lesser extent, standard 1-loop perturbation theory are fairly successful at explaining the nonlinear evolution of the Fourier power spectrum of our models. Analytic models also explain why the ξ(r) peak shifts much more for n=-1.5 than for n≥-1, though no ab initio model we have examined reproduces all of our numerical results. Simulations with L box =10r bao and L box =20r bao yield consistent results for ξ(r) at the BAO scale, provided one corrects for the integral constraint imposed by the uniform density box.

  19. Benchmarking Big Data Systems and the BigData Top100 List.

    Science.gov (United States)

    Baru, Chaitanya; Bhandarkar, Milind; Nambiar, Raghunath; Poess, Meikel; Rabl, Tilmann

    2013-03-01

    "Big data" has become a major force of innovation across enterprises of all sizes. New platforms with increasingly more features for managing big datasets are being announced almost on a weekly basis. Yet, there is currently a lack of any means of comparability among such platforms. While the performance of traditional database systems is well understood and measured by long-established institutions such as the Transaction Processing Performance Council (TCP), there is neither a clear definition of the performance of big data systems nor a generally agreed upon metric for comparing these systems. In this article, we describe a community-based effort for defining a big data benchmark. Over the past year, a Big Data Benchmarking Community has become established in order to fill this void. The effort focuses on defining an end-to-end application-layer benchmark for measuring the performance of big data applications, with the ability to easily adapt the benchmark specification to evolving challenges in the big data space. This article describes the efforts that have been undertaken thus far toward the definition of a BigData Top100 List. While highlighting the major technical as well as organizational challenges, through this article, we also solicit community input into this process.

  20. Evaluating the solution from MrBUMP and BALBES

    Science.gov (United States)

    Keegan, Ronan M.; Long, Fei; Fazio, Vincent J.; Winn, Martyn D.; Murshudov, Garib N.; Vagin, Alexei A.

    2011-01-01

    Molecular replacement is one of the key methods used to solve the problem of determining the phases of structure factors in protein structure solution from X-ray image diffraction data. Its success rate has been steadily improving with the development of improved software methods and the increasing number of structures available in the PDB for use as search models. Despite this, in cases where there is low sequence identity between the target-structure sequence and that of its set of possible homologues it can be a difficult and time-consuming chore to isolate and prepare the best search model for molecular replacement. MrBUMP and BALBES are two recent developments from CCP4 that have been designed to automate and speed up the process of determining and preparing the best search models and putting them through molecular replacement. Their intention is to provide the user with a broad set of results using many search models and to highlight the best of these for further processing. An overview of both programs is presented along with a description of how best to use them, citing case studies and the results of large-scale testing of the software. PMID:21460449

  1. Big data, big knowledge: big data for personalized healthcare.

    Science.gov (United States)

    Viceconti, Marco; Hunter, Peter; Hose, Rod

    2015-07-01

    The idea that the purely phenomenological knowledge that we can extract by analyzing large amounts of data can be useful in healthcare seems to contradict the desire of VPH researchers to build detailed mechanistic models for individual patients. But in practice no model is ever entirely phenomenological or entirely mechanistic. We propose in this position paper that big data analytics can be successfully combined with VPH technologies to produce robust and effective in silico medicine solutions. In order to do this, big data technologies must be further developed to cope with some specific requirements that emerge from this application. Such requirements are: working with sensitive data; analytics of complex and heterogeneous data spaces, including nontextual information; distributed data management under security and performance constraints; specialized analytics to integrate bioinformatics and systems biology information with clinical observations at tissue, organ and organisms scales; and specialized analytics to define the "physiological envelope" during the daily life of each patient. These domain-specific requirements suggest a need for targeted funding, in which big data technologies for in silico medicine becomes the research priority.

  2. BigDataBench: a Big Data Benchmark Suite from Internet Services

    OpenAIRE

    Wang, Lei; Zhan, Jianfeng; Luo, Chunjie; Zhu, Yuqing; Yang, Qiang; He, Yongqiang; Gao, Wanling; Jia, Zhen; Shi, Yingjie; Zhang, Shujie; Zheng, Chen; Lu, Gang; Zhan, Kent; Li, Xiaona; Qiu, Bizhu

    2014-01-01

    As architecture, systems, and data management communities pay greater attention to innovative big data systems and architectures, the pressure of benchmarking and evaluating these systems rises. Considering the broad use of big data systems, big data benchmarks must include diversity of data and workloads. Most of the state-of-the-art big data benchmarking efforts target evaluating specific types of applications or system software stacks, and hence they are not qualified for serving the purpo...

  3. Conociendo Big Data

    Directory of Open Access Journals (Sweden)

    Juan José Camargo-Vega

    2014-12-01

    Full Text Available Teniendo en cuenta la importancia que ha adquirido el término Big Data, la presente investigación buscó estudiar y analizar de manera exhaustiva el estado del arte del Big Data; además, y como segundo objetivo, analizó las características, las herramientas, las tecnologías, los modelos y los estándares relacionados con Big Data, y por último buscó identificar las características más relevantes en la gestión de Big Data, para que con ello se pueda conocer todo lo concerniente al tema central de la investigación.La metodología utilizada incluyó revisar el estado del arte de Big Data y enseñar su situación actual; conocer las tecnologías de Big Data; presentar algunas de las bases de datos NoSQL, que son las que permiten procesar datos con formatos no estructurados, y mostrar los modelos de datos y las tecnologías de análisis de ellos, para terminar con algunos beneficios de Big Data.El diseño metodológico usado para la investigación fue no experimental, pues no se manipulan variables, y de tipo exploratorio, debido a que con esta investigación se empieza a conocer el ambiente del Big Data.

  4. NOAA TIFF Image - 50m Backscatter, Charleston Bump - Deep Coral Priority Areas - NOAA Ship Thomas Jefferson - (2007), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the backscatter intensity of the Charleston Bump off of the South Atlantic Bight,...

  5. NOAA TIFF Image - 30m Slope, Charleston Bump - Deep Coral Priority Areas - R/V Maurice Ewing - (1997), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the backscatter intensity of the Charleston Bump off of the South Atlantic Bight,...

  6. NOAA TIFF Image - 30m Backscatter, Charleston Bump - Deep Coral Priority Areas - NOAA Ship Thomas Jefferson - (2007), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the backscatter intensity of the Charleston Bump off of the South Atlantic Bight,...

  7. NOAA TIFF Image - 30m Rugosity, Charleston Bump - Deep Coral Priority Areas - R/V Maurice Ewing - (1997), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the backscatter intensity of the Charleston Bump off of the South Atlantic Bight,...

  8. BigDansing

    KAUST Repository

    Khayyat, Zuhair

    2015-06-02

    Data cleansing approaches have usually focused on detecting and fixing errors with little attention to scaling to big datasets. This presents a serious impediment since data cleansing often involves costly computations such as enumerating pairs of tuples, handling inequality joins, and dealing with user-defined functions. In this paper, we present BigDansing, a Big Data Cleansing system to tackle efficiency, scalability, and ease-of-use issues in data cleansing. The system can run on top of most common general purpose data processing platforms, ranging from DBMSs to MapReduce-like frameworks. A user-friendly programming interface allows users to express data quality rules both declaratively and procedurally, with no requirement of being aware of the underlying distributed platform. BigDansing takes these rules into a series of transformations that enable distributed computations and several optimizations, such as shared scans and specialized joins operators. Experimental results on both synthetic and real datasets show that BigDansing outperforms existing baseline systems up to more than two orders of magnitude without sacrificing the quality provided by the repair algorithms.

  9. NOAA TIFF Image - 30m Rugosity, Charleston Bump - Deep Coral Priority Areas - R/V Maurice Ewing - (1997), UTM 17N NAD83

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a unified GeoTiff with 30x30 meter cell size representing the bathymetry of the Charleston Bump off of the South Atlantic Bight, derived from...

  10. Characterizing Big Data Management

    Directory of Open Access Journals (Sweden)

    Rogério Rossi

    2015-06-01

    Full Text Available Big data management is a reality for an increasing number of organizations in many areas and represents a set of challenges involving big data modeling, storage and retrieval, analysis and visualization. However, technological resources, people and processes are crucial to facilitate the management of big data in any kind of organization, allowing information and knowledge from a large volume of data to support decision-making. Big data management can be supported by these three dimensions: technology, people and processes. Hence, this article discusses these dimensions: the technological dimension that is related to storage, analytics and visualization of big data; the human aspects of big data; and, in addition, the process management dimension that involves in a technological and business approach the aspects of big data management.

  11. Big science

    CERN Multimedia

    Nadis, S

    2003-01-01

    " "Big science" is moving into astronomy, bringing large experimental teams, multi-year research projects, and big budgets. If this is the wave of the future, why are some astronomers bucking the trend?" (2 pages).

  12. String theory and pre-big bang cosmology

    Science.gov (United States)

    Gasperini, M.; Veneziano, G.

    2016-09-01

    In string theory, the traditional picture of a Universe that emerges from the inflation of a very small and highly curved space-time patch is a possibility, not a necessity: quite different initial conditions are possible, and not necessarily unlikely. In particular, the duality symmetries of string theory suggest scenarios in which the Universe starts inflating from an initial state characterized by very small curvature and interactions. Such a state, being gravitationally unstable, will evolve towards higher curvature and coupling, until string-size effects and loop corrections make the Universe "bounce" into a standard, decreasing-curvature regime. In such a context, the hot big bang of conventional cosmology is replaced by a "hot big bounce" in which the bouncing and heating mechanisms originate from the quantum production of particles in the high-curvature, large-coupling pre-bounce phase. Here we briefly summarize the main features of this inflationary scenario, proposed a quarter century ago. In its simplest version (where it represents an alternative and not a complement to standard slow-roll inflation) it can produce a viable spectrum of density perturbations, together with a tensor component characterized by a "blue" spectral index with a peak in the GHz frequency range. That means, phenomenologically, a very small contribution to a primordial B-mode in the CMB polarization, and the possibility of a large enough stochastic background of gravitational waves to be measurable by present or future gravitational wave detectors.

  13. High-luminosity blue and blue-green gallium nitride light-emitting diodes.

    Science.gov (United States)

    Morkoç, H; Mohammad, S N

    1995-01-06

    Compact and efficient sources of blue light for full color display applications and lighting eluded and tantalized researchers for many years. Semiconductor light sources are attractive owing to their reliability and amenability to mass manufacture. However, large band gaps are required to achieve blue color. A class of compound semiconductors formed by metal nitrides, GaN and its allied compounds AIGaN and InGaN, exhibits properties well suited for not only blue and blue-green emitters, but also for ultraviolet emitters and detectors. What thwarted engineers and scientists from fabricating useful devices from these materials in the past was the poor quality of material and lack of p-type doping. Both of these obstacles have recently been overcome to the point where highluminosity blue and blue-green light-emitting diodes are now available in the marketplace.

  14. Big bang and big crunch in matrix string theory

    OpenAIRE

    Bedford, J; Papageorgakis, C; Rodríguez-Gómez, D; Ward, J

    2007-01-01

    Following the holographic description of linear dilaton null Cosmologies with a Big Bang in terms of Matrix String Theory put forward by Craps, Sethi and Verlinde, we propose an extended background describing a Universe including both Big Bang and Big Crunch singularities. This belongs to a class of exact string backgrounds and is perturbative in the string coupling far away from the singularities, both of which can be resolved using Matrix String Theory. We provide a simple theory capable of...

  15. Bliver big data til big business?

    DEFF Research Database (Denmark)

    Ritter, Thomas

    2015-01-01

    Danmark har en digital infrastruktur, en registreringskultur og it-kompetente medarbejdere og kunder, som muliggør en førerposition, men kun hvis virksomhederne gør sig klar til næste big data-bølge.......Danmark har en digital infrastruktur, en registreringskultur og it-kompetente medarbejdere og kunder, som muliggør en førerposition, men kun hvis virksomhederne gør sig klar til næste big data-bølge....

  16. Big data uncertainties.

    Science.gov (United States)

    Maugis, Pierre-André G

    2018-07-01

    Big data-the idea that an always-larger volume of information is being constantly recorded-suggests that new problems can now be subjected to scientific scrutiny. However, can classical statistical methods be used directly on big data? We analyze the problem by looking at two known pitfalls of big datasets. First, that they are biased, in the sense that they do not offer a complete view of the populations under consideration. Second, that they present a weak but pervasive level of dependence between all their components. In both cases we observe that the uncertainty of the conclusion obtained by statistical methods is increased when used on big data, either because of a systematic error (bias), or because of a larger degree of randomness (increased variance). We argue that the key challenge raised by big data is not only how to use big data to tackle new problems, but to develop tools and methods able to rigorously articulate the new risks therein. Copyright © 2016. Published by Elsevier Ltd.

  17. Investigation of turbulent boundary layer flow over 2D bump using highly resolved large eddy simulation

    DEFF Research Database (Denmark)

    Cavar, Dalibor; Meyer, Knud Erik

    2011-01-01

    A large eddy simulation (LES) study of turbulent non-equilibrium boundary layer flow over 2 D Bump, at comparatively low Reynolds number Reh = U∞h/ν = 1950, was conducted. A well-known LES issue of obtaining and sustaining turbulent flow inside the computational domain at such low Re, is addresse...... partially confirm a close interdependency between generation and evolution of internal layers and the abrupt changes in the skin friction, previously reported in the literature. © 2011 American Society of Mechanical Engineers....

  18. Blue ocean strategy.

    Science.gov (United States)

    Kim, W Chan; Mauborgne, Renée

    2004-10-01

    Despite a long-term decline in the circus industry, Cirque du Soleil profitably increased revenue 22-fold over the last ten years by reinventing the circus. Rather than competing within the confines of the existing industry or trying to steal customers from rivals, Cirque developed uncontested market space that made the competition irrelevant. Cirque created what the authors call a blue ocean, a previously unknown market space. In blue oceans, demand is created rather than fought over. There is ample opportunity for growth that is both profitable and rapid. In red oceans--that is, in all the industries already existing--companies compete by grabbing for a greater share of limited demand. As the market space gets more crowded, prospects for profits and growth decline. Products turn into commodities, and increasing competition turns the water bloody. There are two ways to create blue oceans. One is to launch completely new industries, as eBay did with online auctions. But it's much more common for a blue ocean to be created from within a red ocean when a company expands the boundaries of an existing industry. In studying more than 150 blue ocean creations in over 30 industries, the authors observed that the traditional units of strategic analysis--company and industry--are of limited use in explaining how and why blue oceans are created. The most appropriate unit of analysis is the strategic move, the set of managerial actions and decisions involved in making a major market-creating business offering. Creating blue oceans builds brands. So powerful is blue ocean strategy, in fact, that a blue ocean strategic move can create brand equity that lasts for decades.

  19. HARNESSING BIG DATA VOLUMES

    Directory of Open Access Journals (Sweden)

    Bogdan DINU

    2014-04-01

    Full Text Available Big Data can revolutionize humanity. Hidden within the huge amounts and variety of the data we are creating we may find information, facts, social insights and benchmarks that were once virtually impossible to find or were simply inexistent. Large volumes of data allow organizations to tap in real time the full potential of all the internal or external information they possess. Big data calls for quick decisions and innovative ways to assist customers and the society as a whole. Big data platforms and product portfolio will help customers harness to the full the value of big data volumes. This paper deals with technical and technological issues related to handling big data volumes in the Big Data environment.

  20. Electronic properties of blue phosphorene/graphene and blue phosphorene/graphene-like gallium nitride heterostructures.

    Science.gov (United States)

    Sun, Minglei; Chou, Jyh-Pin; Yu, Jin; Tang, Wencheng

    2017-07-05

    Blue phosphorene (BlueP) is a graphene-like phosphorus nanosheet which was synthesized very recently for the first time [Nano Lett., 2016, 16, 4903-4908]. The combination of electronic properties of two different two-dimensional materials in an ultrathin van der Waals (vdW) vertical heterostructure has been proved to be an effective approach to the design of novel electronic and optoelectronic devices. Therefore, we used density functional theory to investigate the structural and electronic properties of two BlueP-based heterostructures - BlueP/graphene (BlueP/G) and BlueP/graphene-like gallium nitride (BlueP/g-GaN). Our results showed that the semiconducting nature of BlueP and the Dirac cone of G are well preserved in the BlueP/G vdW heterostructure. Moreover, by applying a perpendicular electric field, it is possible to tune the position of the Dirac cone of G with respect to the band edge of BlueP, resulting in the ability to control the Schottky barrier height. For the BlueP/g-GaN vdW heterostructure, BlueP forms an interface with g-GaN with a type-II band alignment, which is a promising feature for unipolar electronic device applications. Furthermore, we discovered that both G and g-GaN can be used as an active layer for BlueP to facilitate charge injection and enhance the device performance.

  1. Big bang and big crunch in matrix string theory

    International Nuclear Information System (INIS)

    Bedford, J.; Ward, J.; Papageorgakis, C.; Rodriguez-Gomez, D.

    2007-01-01

    Following the holographic description of linear dilaton null cosmologies with a big bang in terms of matrix string theory put forward by Craps, Sethi, and Verlinde, we propose an extended background describing a universe including both big bang and big crunch singularities. This belongs to a class of exact string backgrounds and is perturbative in the string coupling far away from the singularities, both of which can be resolved using matrix string theory. We provide a simple theory capable of describing the complete evolution of this closed universe

  2. Big data a primer

    CERN Document Server

    Bhuyan, Prachet; Chenthati, Deepak

    2015-01-01

    This book is a collection of chapters written by experts on various aspects of big data. The book aims to explain what big data is and how it is stored and used. The book starts from  the fundamentals and builds up from there. It is intended to serve as a review of the state-of-the-practice in the field of big data handling. The traditional framework of relational databases can no longer provide appropriate solutions for handling big data and making it available and useful to users scattered around the globe. The study of big data covers a wide range of issues including management of heterogeneous data, big data frameworks, change management, finding patterns in data usage and evolution, data as a service, service-generated data, service management, privacy and security. All of these aspects are touched upon in this book. It also discusses big data applications in different domains. The book will prove useful to students, researchers, and practicing database and networking engineers.

  3. Aerodynamic Drag Reduction for a Generic Truck Using Geometrically Optimized Rear Cabin Bumps

    Directory of Open Access Journals (Sweden)

    Abdellah Ait Moussa

    2015-01-01

    Full Text Available The continuous surge in gas prices has raised major concerns about vehicle fuel efficiency, and drag reduction devices offer a promising strategy. In this paper, we investigate the mechanisms by which geometrically optimized bumps, placed on the rear end of the cabin roof of a generic truck, reduce aerodynamic drag. The incorporation of these devices requires proper choices of the size, location, and overall geometry. In the following analysis we identify these factors using a novel methodology. The numerical technique combines automatic modeling of the add-ons, computational fluid dynamics and optimization using orthogonal arrays, and probabilistic restarts. Numerical results showed reduction in aerodynamic drag between 6% and 10%.

  4. Microsoft big data solutions

    CERN Document Server

    Jorgensen, Adam; Welch, John; Clark, Dan; Price, Christopher; Mitchell, Brian

    2014-01-01

    Tap the power of Big Data with Microsoft technologies Big Data is here, and Microsoft's new Big Data platform is a valuable tool to help your company get the very most out of it. This timely book shows you how to use HDInsight along with HortonWorks Data Platform for Windows to store, manage, analyze, and share Big Data throughout the enterprise. Focusing primarily on Microsoft and HortonWorks technologies but also covering open source tools, Microsoft Big Data Solutions explains best practices, covers on-premises and cloud-based solutions, and features valuable case studies. Best of all,

  5. Summary big data

    CERN Document Server

    2014-01-01

    This work offers a summary of Cukier the book: "Big Data: A Revolution That Will Transform How we Live, Work, and Think" by Viktor Mayer-Schonberg and Kenneth. Summary of the ideas in Viktor Mayer-Schonberg's and Kenneth Cukier's book: " Big Data " explains that big data is where we use huge quantities of data to make better predictions based on the fact we identify patters in the data rather than trying to understand the underlying causes in more detail. This summary highlights that big data will be a source of new economic value and innovation in the future. Moreover, it shows that it will

  6. The Bright γ-ray Flare of 3C 279 in 2015 June: AGILE Detection and Multifrequency Follow-up Observations

    Science.gov (United States)

    Pittori, C.; Lucarelli, F.; Verrecchia, F.; Raiteri, C. M.; Villata, M.; Vittorini, V.; Tavani, M.; Puccetti, S.; Perri, M.; Donnarumma, I.; Vercellone, S.; Acosta-Pulido, J. A.; Bachev, R.; Benítez, E.; Borman, G. A.; Carnerero, M. I.; Carosati, D.; Chen, W. P.; Ehgamberdiev, Sh. A.; Goded, A.; Grishina, T. S.; Hiriart, D.; Hsiao, H. Y.; Jorstad, S. G.; Kimeridze, G. N.; Kopatskaya, E. N.; Kurtanidze, O. M.; Kurtanidze, S. O.; Larionov, V. M.; Larionova, L. V.; Marscher, A. P.; Mirzaqulov, D. O.; Morozova, D. A.; Nilsson, K.; Samal, M. R.; Sigua, L. A.; Spassov, B.; Strigachev, A.; Takalo, L. O.; Antonelli, L. A.; Bulgarelli, A.; Cattaneo, P.; Colafrancesco, S.; Giommi, P.; Longo, F.; Morselli, A.; Paoletti, F.

    2018-04-01

    We report the AGILE detection and the results of the multifrequency follow-up observations of a bright γ-ray flare of the blazar 3C 279 in 2015 June. We use AGILE and Fermi gamma-ray data, together with Swift X-ray andoptical-ultraviolet data, and ground-based GASP-WEBT optical observations, including polarization information, to study the source variability and the overall spectral energy distribution during the γ-ray flare. The γ-ray flaring data, compared with as yet unpublished simultaneous optical data that will allow constraints on the big blue bump disk luminosity, show very high Compton dominance values of ∼100, with the ratio of γ-ray to optical emission rising by a factor of three in a few hours. The multiwavelength behavior of the source during the flare challenges one-zone leptonic theoretical models. The new observations during the 2015 June flare are also compared with already published data and nonsimultaneous historical 3C 279 archival data.

  7. Soldering-induced Cu diffusion and intermetallic compound formation between Ni/Cu under bump metallization and SnPb flip-chip solder bumps

    Science.gov (United States)

    Huang, Chien-Sheng; Jang, Guh-Yaw; Duh, Jenq-Gong

    2004-04-01

    Nickel-based under bump metallization (UBM) has been widely used as a diffusion barrier to prevent the rapid reaction between the Cu conductor and Sn-based solders. In this study, joints with and without solder after heat treatments were employed to evaluate the diffusion behavior of Cu in the 63Sn-37Pb/Ni/Cu/Ti/Si3N4/Si multilayer structure. The atomic flux of Cu diffused through Ni was evaluated from the concentration profiles of Cu in solder joints. During reflow, the atomic flux of Cu was on the order of 1015-1016 atoms/cm2s. However, in the assembly without solder, no Cu was detected on the surface of Ni even after ten cycles of reflow. The diffusion behavior of Cu during heat treatments was studied, and the soldering-process-induced Cu diffusion through Ni metallization was characterized. In addition, the effect of Cu content in the solder near the solder/intermetallic compound (IMC) interface on interfacial reactions between the solder and the Ni/Cu UBM was also discussed. It is evident that the (Cu,Ni)6Sn5 IMC might form as the concentration of Cu in the Sn-Cu-Ni alloy exceeds 0.6 wt.%.

  8. IRON OPACITY BUMP CHANGES THE STABILITY AND STRUCTURE OF ACCRETION DISKS IN ACTIVE GALACTIC NUCLEI

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Yan-Fei [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Davis, Shane W. [Department of Astronomy, University of Virginia, P.O. Box 400325, Charlottesville, VA 22904-4325 (United States); Stone, James M. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States)

    2016-08-10

    Accretion disks around supermassive black holes have regions where the Rosseland mean opacity can be larger than the electron scattering opacity due to the large number of bound–bound transitions in iron. We study the effects of this iron opacity “bump” on the thermal stability and vertical structure of radiation-pressure-dominated accretion disks, utilizing three-dimensional radiation magnetohydrodynamic (MHD) simulations in the local shearing box approximation. The simulations self-consistently calculate the heating due to MHD turbulence caused by magneto-rotational instability and radiative cooling by using the radiative transfer module based on a variable Eddington tensor in Athena. For a 5 × 10{sup 8} solar mass black hole with ∼3% of the Eddington luminosity, a model including the iron opacity bump maintains its structure for more than 10 thermal times without showing significant signs of thermal runaway. In contrast, if only electron scattering and free–free opacity are included as in the standard thin disk model, the disk collapses on the thermal timescale. The difference is caused by a combination of (1) an anti-correlation between the total optical depth and the midplane pressure, and (2) enhanced vertical advective energy transport. These results suggest that the iron opacity bump may have a strong impact on the stability and structure of active galactic nucleus (AGN) accretion disks, and may contribute to a dependence of AGN properties on metallicity. Since this opacity is relevant primarily in UV emitting regions of the flow, it may help to explain discrepancies between observation and theory that are unique to AGNs.

  9. Big Data en surveillance, deel 1 : Definities en discussies omtrent Big Data

    NARCIS (Netherlands)

    Timan, Tjerk

    2016-01-01

    Naar aanleiding van een (vrij kort) college over surveillance en Big Data, werd me gevraagd iets dieper in te gaan op het thema, definities en verschillende vraagstukken die te maken hebben met big data. In dit eerste deel zal ik proberen e.e.a. uiteen te zetten betreft Big Data theorie en

  10. Dermatoscopy of blue vitiligo.

    Science.gov (United States)

    Chandrashekar, L

    2009-07-01

    Blue vitiligo is a distinct variant of vitiligo characterized by a blue-grey appearance of the skin, which corresponds histologically with absence of epidermal melanocytes and presence of numerous dermal melanophages. A 23-year-old woman of Indian origin with Fitzpatrick skin type V presented with a 1-month history of normoaesthetic depigmented macules over the right forearm, dorsa of the hands and right areola. The macule over the right forearm had a bluish tinge. A clinical diagnosis of vitiligo vulgaris with blue vitiligo was made. Dermatoscopy of the interface between the blue macule and the hypopigmented macule revealed a linear depigmented macule in the centre with multiple blue dots and absence of epidermal melanin on the side of the blue macule, and reticular pigmentation with a few depigmented macules and scattered blue dots over the side of the hypopigmented macule. Blue vitiligo was described previously in a patient seropositive for human immunodeficiency virus, and believed to represent postinflammatory hyperpigmentation in areas bordering the vitiliginous patches as a result of psoralen ultraviolet A treatment. This case is unusual because of its rarity and the description of the associated dermatoscopical findings.

  11. Characterizing Big Data Management

    OpenAIRE

    Rogério Rossi; Kechi Hirama

    2015-01-01

    Big data management is a reality for an increasing number of organizations in many areas and represents a set of challenges involving big data modeling, storage and retrieval, analysis and visualization. However, technological resources, people and processes are crucial to facilitate the management of big data in any kind of organization, allowing information and knowledge from a large volume of data to support decision-making. Big data management can be supported by these three dimensions: t...

  12. Blood pressure self-monitoring in pregnancy (BuMP) feasibility study; a qualitative analysis of women's experiences of self-monitoring.

    Science.gov (United States)

    Hinton, Lisa; Tucker, Katherine L; Greenfield, Sheila M; Hodgkinson, James A; Mackillop, Lucy; McCourt, Christine; Carver, Trisha; Crawford, Carole; Glogowska, Margaret; Locock, Louise; Selwood, Mary; Taylor, Kathryn S; McManus, Richard J

    2017-12-19

    Hypertensive disorders in pregnancy are a leading cause of maternal and fetal morbidity worldwide. Raised blood pressure (BP) affects 10% of pregnancies worldwide, of which almost half develop pre-eclampsia. The proportion of pregnant women who have risk factors for pre-eclampsia (such as pre-existing hypertension, obesity and advanced maternal age) is increasing. Pre-eclampsia can manifest itself before women experience symptoms and can develop between antenatal visits. Incentives to improve early detection of gestational hypertensive disorders are therefore strong and self-monitoring of blood pressure (SMBP) in pregnancy might be one means to achieve this, whilst improving women's involvement in antenatal care. The Blood Pressure Self-Monitoring in Pregnancy (BuMP) study aimed to evaluate the feasibility and acceptability of SMBP in pregnancy. To understand women's experiences of SMBP during pregnancy, we undertook a qualitative study embedded within the BuMP observational feasibility study. Women who were at higher risk of developing hypertension and/or pre-eclampsia were invited to take part in a study using SMBP and also invited to take part in an interview. Semi-structured interviews were conducted at the women's homes in Oxfordshire and Birmingham with women who were self-monitoring their BP as part of the BuMP feasibility study in 2014. Interviews were conducted by a qualitative researcher and transcribed verbatim. A framework approach was used for analysis. Fifteen women agreed to be interviewed. Respondents reported general willingness to engage with monitoring their own BP, feeling that it could reduce anxiety around their health during pregnancy, particularly if they had previous experience of raised BP or pre-eclampsia. They felt able to incorporate self-monitoring into their weekly routines, although this was harder post-partum. Self-monitoring of BP made them more aware of the risks of hypertension and pre-eclampsia in pregnancy. Feelings of

  13. Use and selection of bridges as day roosts by Rafinesque's Big Eared Bats.

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, Frances, M.; Loeb, Susan, C.; Bunch, Mary, S.; Bowerman, William, W.

    2008-03-01

    ABSTRACT.—Rafinesque’s big-eared bats (Corynorhinus rafinesquii) use bridges as day roosts in parts of their range, but information on bridge use across their range is lacking. From May to Aug. 2002 we surveyed 1129 bridges (12.5%) within all 46 counties of South Carolina to determine use and selection of bridges as day roosts by big-eared bats and to document their distribution across the state. During summer 2003, we visited 235 bridges in previously occupied areas of the state to evaluate short-term fidelity to bridge roosts. We found colonies and solitary big-eared bats beneath 38 bridges in 2002 and 54 bridges in 2003. Construction type and size of bridges strongly influenced use in both years; bats selected large, concrete girder bridges and avoided flat-bottomed slab bridges. The majority of occupied bridges (94.7%) were in the Upper and Lower Coastal Plains, but a few bridges (5.3%) were located in the Piedmont. Rafinesque’s big-eared bats were absent beneath bridges in the Blue Ridge Mountains. We established new records of occurrence for 10 counties. In the Coastal Plains, big-eared bats exhibited a high degree of short-term fidelity to roosts in highway bridges. For bridges that were occupied at least once, mean frequency of use was 65.9%. Probability of finding bats under a bridge ranged from 0.46 to 0.73 depending on whether the bridge was occupied in the previous year. Thus, bridges should be inspected three to five times in a given year to determine whether they are being used. Regional bridge roost surveys may be a good method for determining the distribution of C. rafinesquii, particularly in the Coastal Plains, and protection of suitable bridges may be a viable conservation strategy where natural roost sites are limited.

  14. Big Data in der Cloud

    DEFF Research Database (Denmark)

    Leimbach, Timo; Bachlechner, Daniel

    2014-01-01

    Technology assessment of big data, in particular cloud based big data services, for the Office for Technology Assessment at the German federal parliament (Bundestag)......Technology assessment of big data, in particular cloud based big data services, for the Office for Technology Assessment at the German federal parliament (Bundestag)...

  15. An analysis of cross-sectional differences in big and non-big public accounting firms' audit programs

    NARCIS (Netherlands)

    Blokdijk, J.H. (Hans); Drieenhuizen, F.; Stein, M.T.; Simunic, D.A.

    2006-01-01

    A significant body of prior research has shown that audits by the Big 5 (now Big 4) public accounting firms are quality differentiated relative to non-Big 5 audits. This result can be derived analytically by assuming that Big 5 and non-Big 5 firms face different loss functions for "audit failures"

  16. Big Data is invading big places as CERN

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    Big Data technologies are becoming more popular with the constant grow of data generation in different fields such as social networks, internet of things and laboratories like CERN. How is CERN making use of such technologies? How machine learning is applied at CERN with Big Data technologies? How much data we move and how it is analyzed? All these questions will be answered during the talk.

  17. The big bang

    International Nuclear Information System (INIS)

    Chown, Marcus.

    1987-01-01

    The paper concerns the 'Big Bang' theory of the creation of the Universe 15 thousand million years ago, and traces events which physicists predict occurred soon after the creation. Unified theory of the moment of creation, evidence of an expanding Universe, the X-boson -the particle produced very soon after the big bang and which vanished from the Universe one-hundredth of a second after the big bang, and the fate of the Universe, are all discussed. (U.K.)

  18. Small Big Data Congress 2017

    NARCIS (Netherlands)

    Doorn, J.

    2017-01-01

    TNO, in collaboration with the Big Data Value Center, presents the fourth Small Big Data Congress! Our congress aims at providing an overview of practical and innovative applications based on big data. Do you want to know what is happening in applied research with big data? And what can already be

  19. Big data opportunities and challenges

    CERN Document Server

    2014-01-01

    This ebook aims to give practical guidance for all those who want to understand big data better and learn how to make the most of it. Topics range from big data analysis, mobile big data and managing unstructured data to technologies, governance and intellectual property and security issues surrounding big data.

  20. Big Data and Neuroimaging.

    Science.gov (United States)

    Webb-Vargas, Yenny; Chen, Shaojie; Fisher, Aaron; Mejia, Amanda; Xu, Yuting; Crainiceanu, Ciprian; Caffo, Brian; Lindquist, Martin A

    2017-12-01

    Big Data are of increasing importance in a variety of areas, especially in the biosciences. There is an emerging critical need for Big Data tools and methods, because of the potential impact of advancements in these areas. Importantly, statisticians and statistical thinking have a major role to play in creating meaningful progress in this arena. We would like to emphasize this point in this special issue, as it highlights both the dramatic need for statistical input for Big Data analysis and for a greater number of statisticians working on Big Data problems. We use the field of statistical neuroimaging to demonstrate these points. As such, this paper covers several applications and novel methodological developments of Big Data tools applied to neuroimaging data.

  1. Big Data; A Management Revolution : The emerging role of big data in businesses

    OpenAIRE

    Blasiak, Kevin

    2014-01-01

    Big data is a term that was coined in 2012 and has since then emerged to one of the top trends in business and technology. Big data is an agglomeration of different technologies resulting in data processing capabilities that have been unreached before. Big data is generally characterized by 4 factors. Volume, velocity and variety. These three factors distinct it from the traditional data use. The possibilities to utilize this technology are vast. Big data technology has touch points in differ...

  2. Social big data mining

    CERN Document Server

    Ishikawa, Hiroshi

    2015-01-01

    Social Media. Big Data and Social Data. Hypotheses in the Era of Big Data. Social Big Data Applications. Basic Concepts in Data Mining. Association Rule Mining. Clustering. Classification. Prediction. Web Structure Mining. Web Content Mining. Web Access Log Mining, Information Extraction and Deep Web Mining. Media Mining. Scalability and Outlier Detection.

  3. Thermal bump removal of a crystal monochromator by designing an optimal shape

    Energy Technology Data Exchange (ETDEWEB)

    Micha, Jean-Sébastien, E-mail: micha@esrf.fr [CRG-IF BM32 Beamline, ESRF, 6 rue J. Horowitz, BP 220, 38043 Grenoble (France); UMR SPrAM 5819, CEA-Grenoble/INAC/SPrAM, 17 avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Geaymond, Olivier [CRG-IF BM32 Beamline, ESRF, 6 rue J. Horowitz, BP 220, 38043 Grenoble (France); Institut Néel, CNRS, 25 avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Rieutord, Francois [CRG-IF BM32 Beamline, ESRF, 6 rue J. Horowitz, BP 220, 38043 Grenoble (France); CEA-Grenoble/INAC/NRS, 17 avenue des Martyrs, 38054 Grenoble Cedex 9 (France)

    2013-05-11

    Thermal bump arising at illuminated area of a water cooled monochromator crystal can be considerably reduced by designing an appropriate shape. Temperature and deformation have been simulated by finite element analysis (FEA) computations as a function of few geometrical parameters describing the shape of the crystal. As a result, a new crystal shape has been found which optimizes the throughput of a double crystals monochromator (DCM). Performances of the initial rectangular crystal and the new designed crystal predicted by FEA-based calculations and measured during experimental tests on a synchrotron beamline are reported. General design principles to overcome heat load issues and the objective function using the slope errors derived from FEA results are detailed. Current and foreseen performances at higher load are presented. Finally, advantages and limits of this simple-to-design and cheap solution are discussed.

  4. Cryptography for Big Data Security

    Science.gov (United States)

    2015-07-13

    Cryptography for Big Data Security Book Chapter for Big Data: Storage, Sharing, and Security (3S) Distribution A: Public Release Ariel Hamlin1 Nabil...Email: arkady@ll.mit.edu ii Contents 1 Cryptography for Big Data Security 1 1.1 Introduction...48 Chapter 1 Cryptography for Big Data Security 1.1 Introduction With the amount

  5. Data: Big and Small.

    Science.gov (United States)

    Jones-Schenk, Jan

    2017-02-01

    Big data is a big topic in all leadership circles. Leaders in professional development must develop an understanding of what data are available across the organization that can inform effective planning for forecasting. Collaborating with others to integrate data sets can increase the power of prediction. Big data alone is insufficient to make big decisions. Leaders must find ways to access small data and triangulate multiple types of data to ensure the best decision making. J Contin Educ Nurs. 2017;48(2):60-61. Copyright 2017, SLACK Incorporated.

  6. Big Data Revisited

    DEFF Research Database (Denmark)

    Kallinikos, Jannis; Constantiou, Ioanna

    2015-01-01

    We elaborate on key issues of our paper New games, new rules: big data and the changing context of strategy as a means of addressing some of the concerns raised by the paper’s commentators. We initially deal with the issue of social data and the role it plays in the current data revolution...... and the technological recording of facts. We further discuss the significance of the very mechanisms by which big data is produced as distinct from the very attributes of big data, often discussed in the literature. In the final section of the paper, we qualify the alleged importance of algorithms and claim...... that the structures of data capture and the architectures in which data generation is embedded are fundamental to the phenomenon of big data....

  7. Origin of colour stability in blue/orange/blue stacked phosphorescent white organic light-emitting diodes

    International Nuclear Information System (INIS)

    Kim, Sung Hyun; Jang, Jyongsik; Yook, Kyoung Soo; Lee, Jun Yeob

    2009-01-01

    The origin of colour stability in phosphorescent white organic light-emitting diodes (PHWOLEDs) with a blue/orange/blue stacked emitting structure was studied by monitoring the change in a recombination zone. A balanced recombination zone shift between the blue and the orange light-emitting layers was found to be responsible for the colour stability in the blue/orange/blue stacked PHWOLEDs.

  8. Big Data in industry

    Science.gov (United States)

    Latinović, T. S.; Preradović, D. M.; Barz, C. R.; Latinović, M. T.; Petrica, P. P.; Pop-Vadean, A.

    2016-08-01

    The amount of data at the global level has grown exponentially. Along with this phenomena, we have a need for a new unit of measure like exabyte, zettabyte, and yottabyte as the last unit measures the amount of data. The growth of data gives a situation where the classic systems for the collection, storage, processing, and visualization of data losing the battle with a large amount, speed, and variety of data that is generated continuously. Many of data that is created by the Internet of Things, IoT (cameras, satellites, cars, GPS navigation, etc.). It is our challenge to come up with new technologies and tools for the management and exploitation of these large amounts of data. Big Data is a hot topic in recent years in IT circles. However, Big Data is recognized in the business world, and increasingly in the public administration. This paper proposes an ontology of big data analytics and examines how to enhance business intelligence through big data analytics as a service by presenting a big data analytics services-oriented architecture. This paper also discusses the interrelationship between business intelligence and big data analytics. The proposed approach in this paper might facilitate the research and development of business analytics, big data analytics, and business intelligence as well as intelligent agents.

  9. Big Data Analytics An Overview

    Directory of Open Access Journals (Sweden)

    Jayshree Dwivedi

    2015-08-01

    Full Text Available Big data is a data beyond the storage capacity and beyond the processing power is called big data. Big data term is used for data sets its so large or complex that traditional data it involves data sets with sizes. Big data size is a constantly moving target year by year ranging from a few dozen terabytes to many petabytes of data means like social networking sites the amount of data produced by people is growing rapidly every year. Big data is not only a data rather it become a complete subject which includes various tools techniques and framework. It defines the epidemic possibility and evolvement of data both structured and unstructured. Big data is a set of techniques and technologies that require new forms of assimilate to uncover large hidden values from large datasets that are diverse complex and of a massive scale. It is difficult to work with using most relational database management systems and desktop statistics and visualization packages exacting preferably massively parallel software running on tens hundreds or even thousands of servers. Big data environment is used to grab organize and resolve the various types of data. In this paper we describe applications problems and tools of big data and gives overview of big data.

  10. Urbanising Big

    DEFF Research Database (Denmark)

    Ljungwall, Christer

    2013-01-01

    Development in China raises the question of how big a city can become, and at the same time be sustainable, writes Christer Ljungwall of the Swedish Agency for Growth Policy Analysis.......Development in China raises the question of how big a city can become, and at the same time be sustainable, writes Christer Ljungwall of the Swedish Agency for Growth Policy Analysis....

  11. Big bang nucleosynthesis

    International Nuclear Information System (INIS)

    Boyd, Richard N.

    2001-01-01

    The precision of measurements in modern cosmology has made huge strides in recent years, with measurements of the cosmic microwave background and the determination of the Hubble constant now rivaling the level of precision of the predictions of big bang nucleosynthesis. However, these results are not necessarily consistent with the predictions of the Standard Model of big bang nucleosynthesis. Reconciling these discrepancies may require extensions of the basic tenets of the model, and possibly of the reaction rates that determine the big bang abundances

  12. Corneal edema and permanent blue discoloration of a silicone intraocular lens by methylene blue.

    Science.gov (United States)

    Stevens, Scott; Werner, Liliana; Mamalis, Nick

    2007-01-01

    To report a silicone intraocular lens (IOL) stained blue by inadvertent intraoperative use of methylene blue instead of trypan blue and the results of experimental staining of various lens materials with different concentrations of the same dye. A "blue dye" was used to enhance visualization during capsulorhexis in a patient undergoing phacoemulsification with implantation of a three-piece silicone lens. Postoperatively, the patient presented with corneal edema and a discolored IOL. Various IOL materials were experimentally stained using methylene blue. Sixteen lenses (4 silicone, 4 hydrophobic acrylic, 4 hydrophilic acrylic, and 4 polymethylmethacrylate) were immersed in 0.5 mL of methylene blue at concentrations of 1%, 0.1%, 0.01%, and 0.001%. These lenses were grossly and microscopically evaluated for discoloration 6 and 24 hours after immersion. The corneal edema resolved within 1 month after the initial surgical procedure. After explantation, gross and microscopic analyses of the explanted silicone lens revealed that its surface and internal substance had been permanently stained blue. In the experimental study, all of the lenses except the polymethylmethacrylate lenses were permanently stained by methylene blue. The hydrophilic acrylic lenses showed the most intense blue staining in all dye concentrations. This is the first clinicopathological report of IOL discoloration due to intraocular use of methylene blue. This and other tissue dyes may be commonly found among surgical supplies in the operating room and due diligence is necessary to avoid mistaking these dyes for those commonly used during ocular surgery.

  13. Lidar quantification of bank erosion in Blue Earth County, Minnesota.

    Science.gov (United States)

    Kessler, A C; Gupta, S C; Dolliver, H A S; Thoma, D P

    2012-01-01

    Sediment and phosphorus (P) transport from the Minnesota River Basin to Lake Pepin on the upper Mississippi River has garnered much attention in recent years. However, there is lack of data on the extent of sediment and P contributions from riverbanks vis-à-vis uplands and ravines. Using two light detection and ranging (lidar) data sets taken in 2005 and 2009, a study was undertaken to quantify sediment and associated P losses from riverbanks in Blue Earth County, Minnesota. Volume change in river valleys as a result of bank erosion amounted to 1.71 million m over 4 yr. Volume change closely followed the trend: the Blue Earth River > the Minnesota River at the county's northern edge > the Le Sueur River > the Maple River > the Watonwan River > the Big Cobb River > Perch Creek > Little Cobb River. Using fine sediment content (silt + clay) and bulk density of 37 bank samples representing three parent materials, we estimate bank erosion contributions of 48 to 79% of the measured total suspended solids at the mouth of the Blue Earth and the Le Sueur rivers. Corresponding soluble P and total P contributions ranged from 0.13 to 0.20% and 40 to 49%, respectively. Although tall banks (>3 m high) accounted for 33% of the total length and 63% of the total area, they accounted for 75% of the volume change in river valleys. We conclude that multitemporal lidar data sets are useful in estimating bank erosion and associated P contributions over large scales, and for riverbanks that are not readily accessible for conventional surveying equipment. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  14. The ethics of big data in big agriculture

    OpenAIRE

    Carbonell (Isabelle M.)

    2016-01-01

    This paper examines the ethics of big data in agriculture, focusing on the power asymmetry between farmers and large agribusinesses like Monsanto. Following the recent purchase of Climate Corp., Monsanto is currently the most prominent biotech agribusiness to buy into big data. With wireless sensors on tractors monitoring or dictating every decision a farmer makes, Monsanto can now aggregate large quantities of previously proprietary farming data, enabling a privileged position with unique in...

  15. The big data-big model (BDBM) challenges in ecological research

    Science.gov (United States)

    Luo, Y.

    2015-12-01

    The field of ecology has become a big-data science in the past decades due to development of new sensors used in numerous studies in the ecological community. Many sensor networks have been established to collect data. For example, satellites, such as Terra and OCO-2 among others, have collected data relevant on global carbon cycle. Thousands of field manipulative experiments have been conducted to examine feedback of terrestrial carbon cycle to global changes. Networks of observations, such as FLUXNET, have measured land processes. In particular, the implementation of the National Ecological Observatory Network (NEON), which is designed to network different kinds of sensors at many locations over the nation, will generate large volumes of ecological data every day. The raw data from sensors from those networks offer an unprecedented opportunity for accelerating advances in our knowledge of ecological processes, educating teachers and students, supporting decision-making, testing ecological theory, and forecasting changes in ecosystem services. Currently, ecologists do not have the infrastructure in place to synthesize massive yet heterogeneous data into resources for decision support. It is urgent to develop an ecological forecasting system that can make the best use of multiple sources of data to assess long-term biosphere change and anticipate future states of ecosystem services at regional and continental scales. Forecasting relies on big models that describe major processes that underlie complex system dynamics. Ecological system models, despite great simplification of the real systems, are still complex in order to address real-world problems. For example, Community Land Model (CLM) incorporates thousands of processes related to energy balance, hydrology, and biogeochemistry. Integration of massive data from multiple big data sources with complex models has to tackle Big Data-Big Model (BDBM) challenges. Those challenges include interoperability of multiple

  16. A Big Video Manifesto

    DEFF Research Database (Denmark)

    Mcilvenny, Paul Bruce; Davidsen, Jacob

    2017-01-01

    and beautiful visualisations. However, we also need to ask what the tools of big data can do both for the Humanities and for more interpretative approaches and methods. Thus, we prefer to explore how the power of computation, new sensor technologies and massive storage can also help with video-based qualitative......For the last few years, we have witnessed a hype about the potential results and insights that quantitative big data can bring to the social sciences. The wonder of big data has moved into education, traffic planning, and disease control with a promise of making things better with big numbers...

  17. Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comfrey (Symphytum officinale).

    Science.gov (United States)

    Mei, Nan; Guo, Lei; Zhang, Lu; Shi, Leming; Sun, Yongming Andrew; Fung, Chris; Moland, Carrie L; Dial, Stacey L; Fuscoe, James C; Chen, Tao

    2006-09-06

    Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock and humans and carcinogenic in experimental animals. Our previous study suggested that comfrey induces liver tumors by a genotoxic mechanism and that the pyrrolizidine alkaloids in the plant are responsible for mutation induction and tumor initiation in rat liver. In this study, we identified comfrey-induced gene expression profile in the livers of rats. Groups of 6 male transgenic Big Blue rats were fed a basal diet and a diet containing 8% comfrey roots, a dose that resulted in liver tumors in a previous carcinogenicity bioassay. The animals were treated for 12 weeks and sacrificed one day after the final treatment. We used a rat microarray containing 26,857 genes to perform genome-wide gene expression studies. Dietary comfrey resulted in marked changes in liver gene expression, as well as in significant decreases in the body weight and increases in liver mutant frequency. When a two-fold cutoff value and a P-value less than 0.01 were selected, 2,726 genes were identified as differentially expressed in comfrey-fed rats compared to control animals. Among these genes, there were 1,617 genes associated by Ingenuity Pathway Analysis with particular functions, and the differentially expressed genes in comfrey-fed rat livers were involved in metabolism, injury of endothelial cells, and liver injury and abnormalities, including liver fibrosis and cancer development. The gene expression profile provides us a better understanding of underlying mechanisms for comfrey-induced hepatic toxicity. Integration of gene expression changes with known pathological changes can be used to formulate a mechanistic scheme for comfrey-induced liver toxicity and tumorigenesis.

  18. Identifying Dwarfs Workloads in Big Data Analytics

    OpenAIRE

    Gao, Wanling; Luo, Chunjie; Zhan, Jianfeng; Ye, Hainan; He, Xiwen; Wang, Lei; Zhu, Yuqing; Tian, Xinhui

    2015-01-01

    Big data benchmarking is particularly important and provides applicable yardsticks for evaluating booming big data systems. However, wide coverage and great complexity of big data computing impose big challenges on big data benchmarking. How can we construct a benchmark suite using a minimum set of units of computation to represent diversity of big data analytics workloads? Big data dwarfs are abstractions of extracting frequently appearing operations in big data computing. One dwarf represen...

  19. Applications of Big Data in Education

    OpenAIRE

    Faisal Kalota

    2015-01-01

    Big Data and analytics have gained a huge momentum in recent years. Big Data feeds into the field of Learning Analytics (LA) that may allow academic institutions to better understand the learners' needs and proactively address them. Hence, it is important to have an understanding of Big Data and its applications. The purpose of this descriptive paper is to provide an overview of Big Data, the technologies used in Big Data, and some of the applications of Big Data in educa...

  20. Big Data Semantics

    NARCIS (Netherlands)

    Ceravolo, Paolo; Azzini, Antonia; Angelini, Marco; Catarci, Tiziana; Cudré-Mauroux, Philippe; Damiani, Ernesto; Mazak, Alexandra; van Keulen, Maurice; Jarrar, Mustafa; Santucci, Giuseppe; Sattler, Kai-Uwe; Scannapieco, Monica; Wimmer, Manuel; Wrembel, Robert; Zaraket, Fadi

    2018-01-01

    Big Data technology has discarded traditional data modeling approaches as no longer applicable to distributed data processing. It is, however, largely recognized that Big Data impose novel challenges in data and infrastructure management. Indeed, multiple components and procedures must be

  1. Blue-Green Algae

    Science.gov (United States)

    ... that taking a specific blue-green algae product (Super Blue-Green Algae, Cell Tech, Klamath Falls, OR) ... system. Premenstrual syndrome (PMS). Depression. Digestion. Heart disease. Memory. Wound healing. Other conditions. More evidence is needed ...

  2. Blue gods, blue oil, and blue people.

    Science.gov (United States)

    Fairbanks, V F

    1994-09-01

    Studies of the composition of coal tar, which began in Prussia in 1834, profoundly affected the economies of Germany, Great Britain, India, and the rest of the world, as well as medicine and surgery. Such effects include the collapse of the profits of the British indigo monopoly, the growth in economic power of Germany based on coal tar chemistry, and an economic crisis in India that led to more humane tax laws and, ultimately, the independence of India and the end of the British Empire. Additional consequences were the development of antiseptic surgery and the synthesis of a wide variety of useful drugs that have eradicated infections and alleviated pain. Many of these drugs, particularly the commonly used analgesics, sulfonamides, sulfones, and local anesthetics, are derivatives of aniline, originally called "blue oil" or "kyanol." Some of these aniline derivatives, however, have also caused aplastic anemia, agranulocytosis, and methemoglobinemia (that is, "blue people"). Exposure to aniline drugs, particularly when two or three aniline drugs are taken concurrently, seems to be the commonest cause of methemoglobinemia today.

  3. Comparative validity of brief to medium-length Big Five and Big Six personality questionnaires

    NARCIS (Netherlands)

    Thalmayer, A.G.; Saucier, G.; Eigenhuis, A.

    2011-01-01

    A general consensus on the Big Five model of personality attributes has been highly generative for the field of personality psychology. Many important psychological and life outcome correlates with Big Five trait dimensions have been established. But researchers must choose between multiple Big Five

  4. [Acute blue urticaria following subcutaneous injection of patent blue dye].

    Science.gov (United States)

    Hamelin, A; Vial-Dupuy, A; Lebrun-Vignes, B; Francès, C; Soria, A; Barete, S

    2015-11-01

    Patent blue (PB) is a lymphatic vessel dye commonly used in France for sentinel lymph node detection in breast cancer, and less frequently in melanoma, and which may induce hypersensitivity reactions. We report a case of acute blue urticaria occurring within minutes of PB injection. Ten minutes after PB injection for sentinel lymph node detection during breast cancer surgery, a 49-year-old woman developed generalised acute blue urticaria and eyelid angioedema without bronchospasm or haemodynamic disturbance, but requiring discontinuation of surgery. Skin testing using PB and the anaesthetics given were run 6 weeks after the episode and confirmed PB allergy. PB was formally contra-indicated. Immediate hypersensitivity reactions to PB have been reported for between 0.24 and 2.2% of procedures. Such reactions are on occasion severe, chiefly involving anaphylactic shock. Two mechanisms are probably associated: non-specific histamine release and/or an IgE-mediated mechanism. Skin tests are helpful in confirming the diagnosis of PB allergy. Blue acute urticaria is one of the clinical manifestations of immediate hypersensitivity reactions to patent blue dye. Skin tests must be performed 6 weeks after the reaction in order to confirm the diagnosis and formally contra-indicate this substance. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  5. Big data need big theory too.

    Science.gov (United States)

    Coveney, Peter V; Dougherty, Edward R; Highfield, Roger R

    2016-11-13

    The current interest in big data, machine learning and data analytics has generated the widespread impression that such methods are capable of solving most problems without the need for conventional scientific methods of inquiry. Interest in these methods is intensifying, accelerated by the ease with which digitized data can be acquired in virtually all fields of endeavour, from science, healthcare and cybersecurity to economics, social sciences and the humanities. In multiscale modelling, machine learning appears to provide a shortcut to reveal correlations of arbitrary complexity between processes at the atomic, molecular, meso- and macroscales. Here, we point out the weaknesses of pure big data approaches with particular focus on biology and medicine, which fail to provide conceptual accounts for the processes to which they are applied. No matter their 'depth' and the sophistication of data-driven methods, such as artificial neural nets, in the end they merely fit curves to existing data. Not only do these methods invariably require far larger quantities of data than anticipated by big data aficionados in order to produce statistically reliable results, but they can also fail in circumstances beyond the range of the data used to train them because they are not designed to model the structural characteristics of the underlying system. We argue that it is vital to use theory as a guide to experimental design for maximal efficiency of data collection and to produce reliable predictive models and conceptual knowledge. Rather than continuing to fund, pursue and promote 'blind' big data projects with massive budgets, we call for more funding to be allocated to the elucidation of the multiscale and stochastic processes controlling the behaviour of complex systems, including those of life, medicine and healthcare.This article is part of the themed issue 'Multiscale modelling at the physics-chemistry-biology interface'. © 2015 The Authors.

  6. Big Data and medicine: a big deal?

    Science.gov (United States)

    Mayer-Schönberger, V; Ingelsson, E

    2018-05-01

    Big Data promises huge benefits for medical research. Looking beyond superficial increases in the amount of data collected, we identify three key areas where Big Data differs from conventional analyses of data samples: (i) data are captured more comprehensively relative to the phenomenon under study; this reduces some bias but surfaces important trade-offs, such as between data quantity and data quality; (ii) data are often analysed using machine learning tools, such as neural networks rather than conventional statistical methods resulting in systems that over time capture insights implicit in data, but remain black boxes, rarely revealing causal connections; and (iii) the purpose of the analyses of data is no longer simply answering existing questions, but hinting at novel ones and generating promising new hypotheses. As a consequence, when performed right, Big Data analyses can accelerate research. Because Big Data approaches differ so fundamentally from small data ones, research structures, processes and mindsets need to adjust. The latent value of data is being reaped through repeated reuse of data, which runs counter to existing practices not only regarding data privacy, but data management more generally. Consequently, we suggest a number of adjustments such as boards reviewing responsible data use, and incentives to facilitate comprehensive data sharing. As data's role changes to a resource of insight, we also need to acknowledge the importance of collecting and making data available as a crucial part of our research endeavours, and reassess our formal processes from career advancement to treatment approval. © 2017 The Association for the Publication of the Journal of Internal Medicine.

  7. Assessing Big Data

    DEFF Research Database (Denmark)

    Leimbach, Timo; Bachlechner, Daniel

    2015-01-01

    In recent years, big data has been one of the most controversially discussed technologies in terms of its possible positive and negative impact. Therefore, the need for technology assessments is obvious. This paper first provides, based on the results of a technology assessment study, an overview...... of the potential and challenges associated with big data and then describes the problems experienced during the study as well as methods found helpful to address them. The paper concludes with reflections on how the insights from the technology assessment study may have an impact on the future governance of big...... data....

  8. Big data, big responsibilities

    Directory of Open Access Journals (Sweden)

    Primavera De Filippi

    2014-01-01

    Full Text Available Big data refers to the collection and aggregation of large quantities of data produced by and about people, things or the interactions between them. With the advent of cloud computing, specialised data centres with powerful computational hardware and software resources can be used for processing and analysing a humongous amount of aggregated data coming from a variety of different sources. The analysis of such data is all the more valuable to the extent that it allows for specific patterns to be found and new correlations to be made between different datasets, so as to eventually deduce or infer new information, as well as to potentially predict behaviours or assess the likelihood for a certain event to occur. This article will focus specifically on the legal and moral obligations of online operators collecting and processing large amounts of data, to investigate the potential implications of big data analysis on the privacy of individual users and on society as a whole.

  9. Jagua blue derived from Genipa americana L. fruit: A natural alternative to commonly used blue food colorants?

    Science.gov (United States)

    Brauch, J E; Zapata-Porras, S P; Buchweitz, M; Aschoff, J K; Carle, R

    2016-11-01

    Due to consumers' increasing health awareness, food industry aims at replacing synthetic dyes by natural counterparts. The substitution of blue synthetic dyes is particularly challenging since current natural alternatives such as phycocyanin (Spirulina) suffer from poor stability. Jagua blue (produced from Genipa americana L. fruit) might represent a potential novel blue pigment source. However, only little is known about its color properties, and application in food systems. Therefore, the blue color and the stability of Jagua blue were assessed for the first time and compared to commonly used colorants, namely, Spirulina, brilliant blue FCF (Blue no. 1), and indigo carmine (Blue no. 2). The reaction rate of Jagua blue was independent of its concentration, confirming thermal degradation to follow first-order kinetics. Between pH 3.6 and 5.0, the color hue of Jagua blue solutions was similar to that of Blue no. 2. However, Jagua blue revealed markedly higher storage stabilities (t 1/2 =86-105days) than Blue no. 2 (t 1 /2 ≤9days) and was less susceptible to acidic pH of 3.6 (t 1 /2 =86days) than Spirulina (t 1 /2 =70days). High negative b* values (blueness) of colored gelatin gels were only obtained for Jagua blue and Spirulina, and the former exhibited higher light stabilities (t 1 /2 =15days) than Spirulina gels (t 1 /2 =4days). Our findings indicate Jagua blue to be a most promising alternative to synthetic dyes, providing relevant information regarding potential food applications. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Comparative validity of brief to medium-length Big Five and Big Six Personality Questionnaires.

    Science.gov (United States)

    Thalmayer, Amber Gayle; Saucier, Gerard; Eigenhuis, Annemarie

    2011-12-01

    A general consensus on the Big Five model of personality attributes has been highly generative for the field of personality psychology. Many important psychological and life outcome correlates with Big Five trait dimensions have been established. But researchers must choose between multiple Big Five inventories when conducting a study and are faced with a variety of options as to inventory length. Furthermore, a 6-factor model has been proposed to extend and update the Big Five model, in part by adding a dimension of Honesty/Humility or Honesty/Propriety. In this study, 3 popular brief to medium-length Big Five measures (NEO Five Factor Inventory, Big Five Inventory [BFI], and International Personality Item Pool), and 3 six-factor measures (HEXACO Personality Inventory, Questionnaire Big Six Scales, and a 6-factor version of the BFI) were placed in competition to best predict important student life outcomes. The effect of test length was investigated by comparing brief versions of most measures (subsets of items) with original versions. Personality questionnaires were administered to undergraduate students (N = 227). Participants' college transcripts and student conduct records were obtained 6-9 months after data was collected. Six-factor inventories demonstrated better predictive ability for life outcomes than did some Big Five inventories. Additional behavioral observations made on participants, including their Facebook profiles and cell-phone text usage, were predicted similarly by Big Five and 6-factor measures. A brief version of the BFI performed surprisingly well; across inventory platforms, increasing test length had little effect on predictive validity. Comparative validity of the models and measures in terms of outcome prediction and parsimony is discussed.

  11. Big Machines and Big Science: 80 Years of Accelerators at Stanford

    Energy Technology Data Exchange (ETDEWEB)

    Loew, Gregory

    2008-12-16

    Longtime SLAC physicist Greg Loew will present a trip through SLAC's origins, highlighting its scientific achievements, and provide a glimpse of the lab's future in 'Big Machines and Big Science: 80 Years of Accelerators at Stanford.'

  12. Dual of big bang and big crunch

    International Nuclear Information System (INIS)

    Bak, Dongsu

    2007-01-01

    Starting from the Janus solution and its gauge theory dual, we obtain the dual gauge theory description of the cosmological solution by the procedure of double analytic continuation. The coupling is driven either to zero or to infinity at the big-bang and big-crunch singularities, which are shown to be related by the S-duality symmetry. In the dual Yang-Mills theory description, these are nonsingular as the coupling goes to zero in the N=4 super Yang-Mills theory. The cosmological singularities simply signal the failure of the supergravity description of the full type IIB superstring theory

  13. On the evolutionary status and pulsations of the recently discovered blue large-amplitude pulsators (BLAPs)

    Science.gov (United States)

    Romero, Alejandra D.; Córsico, A. H.; Althaus, L. G.; Pelisoli, I.; Kepler, S. O.

    2018-06-01

    The blue large-amplitude pulsators (BLAPs) constitute a new class of pulsating stars. They are hot stars with effective temperatures of ˜30 000 K and surface gravities of log g ˜ 4.9, that pulsate with periods in the range 20-40 min. Until now, their origin and evolutionary state, as well as the nature of their pulsations, were not been unveiled. In this paper, we propose that the BLAPs are the hot counterpart of the already known pulsating pre-extremely low mass (pre-ELM) white dwarf (WD) stars, that are He-core low-mass stars resulting from interacting binary evolution. Using fully evolutionary sequences, we show that the BLAPs are well represented by pre-ELM WD models with high effective temperature and stellar masses ˜0.34 M⊙. From the analysis of their pulsational properties, we find that the observed variabilities can be explained by high-order non-radial g-mode pulsations or, in the case of the shortest periods, also by low-order radial modes, including the fundamental radial mode. The theoretical modes with periods in the observed range are unstable due to the κ mechanism associated with the Z-bump in the opacity at log T ˜ 5.25.

  14. The Fictional Black Blues Figure: Blues Music and the Art of Narrative Self-Invention

    OpenAIRE

    Mack, Kimberly

    2015-01-01

    The Fictional Black Blues Figure: Blues Music and the Art of Narrative Self-Invention, Kimberly MackMy dissertation examines representations of black American blues musicians in contemporary American fiction, drama, and popular music, and it argues that blues music can be examined as a narrative art rooted in the tradition of fictionalized autobiographical self-fashioning. I contend that the contemporary, multi-racial, literary and musical characters in my project who participate in so-called...

  15. Comparative Validity of Brief to Medium-Length Big Five and Big Six Personality Questionnaires

    Science.gov (United States)

    Thalmayer, Amber Gayle; Saucier, Gerard; Eigenhuis, Annemarie

    2011-01-01

    A general consensus on the Big Five model of personality attributes has been highly generative for the field of personality psychology. Many important psychological and life outcome correlates with Big Five trait dimensions have been established. But researchers must choose between multiple Big Five inventories when conducting a study and are…

  16. Big data for health.

    Science.gov (United States)

    Andreu-Perez, Javier; Poon, Carmen C Y; Merrifield, Robert D; Wong, Stephen T C; Yang, Guang-Zhong

    2015-07-01

    This paper provides an overview of recent developments in big data in the context of biomedical and health informatics. It outlines the key characteristics of big data and how medical and health informatics, translational bioinformatics, sensor informatics, and imaging informatics will benefit from an integrated approach of piecing together different aspects of personalized information from a diverse range of data sources, both structured and unstructured, covering genomics, proteomics, metabolomics, as well as imaging, clinical diagnosis, and long-term continuous physiological sensing of an individual. It is expected that recent advances in big data will expand our knowledge for testing new hypotheses about disease management from diagnosis to prevention to personalized treatment. The rise of big data, however, also raises challenges in terms of privacy, security, data ownership, data stewardship, and governance. This paper discusses some of the existing activities and future opportunities related to big data for health, outlining some of the key underlying issues that need to be tackled.

  17. Coomassie Brilliant Blue G is a more potent antagonist of P2 purinergic responses than Reactive Blue 2 (Cibacron Blue 3GA) in rat parotid acinar cells

    International Nuclear Information System (INIS)

    Soltoff, S.P.; McMillian, M.K.; Talamo, B.R.

    1989-01-01

    The ability of Brilliant Blue G (Coomassie Brilliant Blue G) and Reactive Blue 2 (Cibacron Blue 3GA) to block the effects of extracellular ATP on rat parotid acinar cells was examined by evaluating their effects on ATP-stimulated 45Ca 2+ entry and the elevation of [Ca 2+ ]i (Fura 2 fluorescence). ATP (300 microM) increased the rate of Ca 2+ entry to more than 25-times the basal rate and elevated [Ca 2+ ]i to levels more than three times the basal value. Brilliant Blue G and Reactive Blue 2 greatly reduced the entry of 45 Ca 2+ into parotid cells, but the potency of Brilliant Blue G (IC50 approximately 0.4 microM) was about 100-times that of Reactive Blue 2. Fura 2 studies demonstrated that inhibitory concentrations of these compounds did not block the cholinergic response of these cells, thus demonstrating the selectivity of the dye compounds for purinergic receptors. Unlike Reactive Blue 2, effective concentrations of Brilliant Blue G did not substantially quench Fura 2 fluorescence. The greater potency of Brilliant Blue G suggests that it may be very useful in identifying P2-type purinergic receptors, especially in studies which utilize fluorescent probes

  18. Measuring Blue Space Visibility and 'Blue Recreation' in the Everyday Lives of Children in a Capital City.

    Science.gov (United States)

    Pearson, Amber L; Bottomley, Ross; Chambers, Tim; Thornton, Lukar; Stanley, James; Smith, Moira; Barr, Michelle; Signal, Louise

    2017-05-26

    Blue spaces (water bodies) may promote positive mental and physical health through opportunities for relaxation, recreation, and social connections. However, we know little about the nature and extent of everyday exposure to blue spaces, particularly in settings outside the home or among children, nor whether exposure varies by individual or household characteristics. Wearable cameras offer a novel, reliable method for blue space exposure measurement. In this study, we used images from cameras worn over two days by 166 children in Wellington, New Zealand, and conducted content and blue space quantification analysis on each image ( n = 749,389). Blue space was identified in 24,721 images (3.6%), with a total of 23 blue recreation events. Visual exposure and participation in blue recreation did not differ by ethnicity, weight status, household deprivation, or residential proximity to the coastline. Significant differences in both visual exposure to blue space and participation in blue recreation were observed, whereby children from the most deprived schools had significantly higher rates of blue space exposure than children from low deprivation schools. Schools may be important settings to promote equitable blue space exposures. Childhood exposures to blue space may not follow the expected income inequality trends observed among adults.

  19. Active methods of preventing bumps in situations where the longwall face advances to and crosses a roadway in thick coal beds

    Energy Technology Data Exchange (ETDEWEB)

    Loboda, C

    1978-01-01

    The method was analyzed in the Wujek coal mine, where the coal bed is located at 600 m and was 5.3 m to 5.7 m thick. The following situation is described: A longwall face had to pass through a ventilation tunnel. To reduce the inner stress of the coal mass above and below the ventilation tunnel infusion was used. Water was forced into the walls of the tunnel. The tunnel section was 200 m long, 28 holes were drilled, each 40 m deep, diameter of the bore 42 to 45 mm, water pressure 300 at. To prevent bumps the orientation of the longwall face, which had been parallel to the ventilation tunnel, was changed so that it was at the angle of 15 degrees to the ventilation tunnel. Experience showed that the most dangerous situation in the tunnel arises when the distance between a longwall face and a roadway is reduced to 45 m. At that moment pressure on the road support system is the greatest. The danger of bumps at a longwall face is the greatest when it is 25 m away from a roadway.

  20. 75 FR 65525 - Anthem Blue Cross Blue Shield, Claim Management Services, Inc. Operations, a Division of...

    Science.gov (United States)

    2010-10-25

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,327] Anthem Blue Cross Blue Shield, Claim Management Services, Inc. Operations, a Division of Wellpoint, Inc., Green Bay, WI; Notice... former workers of Anthem Blue Cross Blue Shield, Claim Management Services, Inc. Operations, a Division...

  1. Dyes adsorption blue vegetable and blue watercolor by natural zeolites modified with surfactants

    International Nuclear Information System (INIS)

    Jardon S, C. C.; Olguin G, M. T.; Diaz N, M. C.

    2009-01-01

    In this work was carried out the dyes removal blue vegetable and blue watercolor of aqueous solutions, to 20 C, at different times and using a zeolite mineral of Parral (Chihuahua, Mexico) modified with hexadecyl trimethyl ammonium bromide or dodecyl trimethyl ammonium bromide. The zeolite was characterized before and after of its adaptation with NaCl and later with HDTMABr and DTMABr. For the materials characterization were used the scanning electron microscopy of high vacuum; elementary microanalysis by X-ray spectroscopy of dispersed energy and X-ray diffraction techniques. It was found that the surfactant type absorbed in the zeolite material influences on the adsorption process of the blue dye. Likewise, the chemical structure between the vegetable blue dye and the blue watercolor, determines the efficiency of the color removal of the water, by the zeolites modified with the surfactants. (Author)

  2. Big Data: Implications for Health System Pharmacy.

    Science.gov (United States)

    Stokes, Laura B; Rogers, Joseph W; Hertig, John B; Weber, Robert J

    2016-07-01

    Big Data refers to datasets that are so large and complex that traditional methods and hardware for collecting, sharing, and analyzing them are not possible. Big Data that is accurate leads to more confident decision making, improved operational efficiency, and reduced costs. The rapid growth of health care information results in Big Data around health services, treatments, and outcomes, and Big Data can be used to analyze the benefit of health system pharmacy services. The goal of this article is to provide a perspective on how Big Data can be applied to health system pharmacy. It will define Big Data, describe the impact of Big Data on population health, review specific implications of Big Data in health system pharmacy, and describe an approach for pharmacy leaders to effectively use Big Data. A few strategies involved in managing Big Data in health system pharmacy include identifying potential opportunities for Big Data, prioritizing those opportunities, protecting privacy concerns, promoting data transparency, and communicating outcomes. As health care information expands in its content and becomes more integrated, Big Data can enhance the development of patient-centered pharmacy services.

  3. Generalized formal model of Big Data

    OpenAIRE

    Shakhovska, N.; Veres, O.; Hirnyak, M.

    2016-01-01

    This article dwells on the basic characteristic features of the Big Data technologies. It is analyzed the existing definition of the “big data” term. The article proposes and describes the elements of the generalized formal model of big data. It is analyzed the peculiarities of the application of the proposed model components. It is described the fundamental differences between Big Data technology and business analytics. Big Data is supported by the distributed file system Google File System ...

  4. BigWig and BigBed: enabling browsing of large distributed datasets.

    Science.gov (United States)

    Kent, W J; Zweig, A S; Barber, G; Hinrichs, A S; Karolchik, D

    2010-09-01

    BigWig and BigBed files are compressed binary indexed files containing data at several resolutions that allow the high-performance display of next-generation sequencing experiment results in the UCSC Genome Browser. The visualization is implemented using a multi-layered software approach that takes advantage of specific capabilities of web-based protocols and Linux and UNIX operating systems files, R trees and various indexing and compression tricks. As a result, only the data needed to support the current browser view is transmitted rather than the entire file, enabling fast remote access to large distributed data sets. Binaries for the BigWig and BigBed creation and parsing utilities may be downloaded at http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/. Source code for the creation and visualization software is freely available for non-commercial use at http://hgdownload.cse.ucsc.edu/admin/jksrc.zip, implemented in C and supported on Linux. The UCSC Genome Browser is available at http://genome.ucsc.edu.

  5. Transient and steady state behaviour of elasto–aerodynamic air foil bearings, considering bump foil compliance and top foil inertia and flexibility: A numerical investigation

    DEFF Research Database (Denmark)

    Nielsen, Bo Bjerregaard; Santos, Ilmar F.

    2017-01-01

    utilise two types of eight-node isoparametric elements. The rotor is modelled as a rigid body without rotational inertia, i.e. as a journal. The bump foil is included via a bilinear version of the simple elastic foundation model. This paper introduces the bilinear simple elastic foundation model, which...

  6. Evaluation of Blue Gum Chalid Infestation Woodlots in Western Kenya

    International Nuclear Information System (INIS)

    Otuoma, J.; Muchiri, M.N

    2007-01-01

    Blue gum chalcid (BGC) Leptocybe invasa is a gall-forming wasp that belongs to the insect order Hymenoptera, family Eulophidae. It attacks a wide range of Eucalyptus species mostly between the seedling stage and five years of age. BGC causes damage to eucalyptus by forming bump-shaped galls on the leaf midribs, petioles and stems.Twisted and knobbed leaves manifest severe infestation. The aim of this study was to establish the spatial distribution of BGC and extent of host plant damage in Eucalyptus woodlots in Western Kenya. The study was carried out in six permanent sampling plots in Eucalyptus woodlots in Busia, Bungoma, Kakamega and Nyando. Trees were assessed for crown damage by estimating and classifying the density of galls on the leaves into four levels of infestation: low (greater than 50% of foliage canopy with galls and no twisted or knobbed leaves), moderate (greater than 50% of foliage with galls and less than 50% of the leaves twisted and knobbed), high (greater than 50% of the leaves twisted and knobbed, galls on the twigs and some twigs deformed and severe (greater than 50% of the twigs deformed and regeneration foliage observed). An evaluation of the pests' infestation and the extent of host plant damage indicated that, 4% of the trees and severe infestation; 5% high; 20% moderate and 70% low. Approximately 1% of trees died as a result of loss of foliage attributable to severe infestation. Other observations from the study were that the severity of BGC infestation tended to decline as trees grew older and BGC infestation retarded tree growth

  7. Big data-driven business how to use big data to win customers, beat competitors, and boost profits

    CERN Document Server

    Glass, Russell

    2014-01-01

    Get the expert perspective and practical advice on big data The Big Data-Driven Business: How to Use Big Data to Win Customers, Beat Competitors, and Boost Profits makes the case that big data is for real, and more than just big hype. The book uses real-life examples-from Nate Silver to Copernicus, and Apple to Blackberry-to demonstrate how the winners of the future will use big data to seek the truth. Written by a marketing journalist and the CEO of a multi-million-dollar B2B marketing platform that reaches more than 90% of the U.S. business population, this book is a comprehens

  8. Geodesic acoustic mode driven by energetic particles with bump-on-tail distribution

    Science.gov (United States)

    Ren, Haijun; Wang, Hao

    2018-04-01

    Energetic-particle-driven geodesic acoustic mode (EGAM) is analytically investigated by adopting the bump-on-tail distribution for energetic particles (EPs), which is created by the fact that the charge exchange time (τcx ) is sufficiently shorter than the slowing down time (τsl ). The dispersion relation is derived in the use of gyro-kinetic equations. Due to the finite ratio of the critical energy and the initial energy of EPs, defined as τc , the dispersion relation is numerically evaluated and the effect of finite τc is examined. Following relative simulation and experimental work, we specifically considered two cases: τsl/τcx = 3.4 and τsl/τcx = 20.4 . The pitch angle is shown to significantly enhance the growth rate and meanwhile, the real frequency is dramatically decreased with increasing pitch angle. The excitation of high-frequency EGAM is found, and this is consistent with both the experiment and the simulation. The number density effect of energetic particles, represented by \

  9. Big Game Reporting Stations

    Data.gov (United States)

    Vermont Center for Geographic Information — Point locations of big game reporting stations. Big game reporting stations are places where hunters can legally report harvested deer, bear, or turkey. These are...

  10. Stalin's Big Fleet Program

    National Research Council Canada - National Science Library

    Mauner, Milan

    2002-01-01

    Although Dr. Milan Hauner's study 'Stalin's Big Fleet program' has focused primarily on the formation of Big Fleets during the Tsarist and Soviet periods of Russia's naval history, there are important lessons...

  11. Simulation studies of plasma waves in the electron foreshock - The generation of Langmuir waves by a gentle bump-on-tail electron distribution

    Science.gov (United States)

    Dum, C. T.

    1990-01-01

    Particle simulation experiments were used to study the basic physical ingredients needed for building a global model of foreshock wave phenomena. In particular, the generation of Langmuir waves by a gentle bump-on-tail electron distribution is analyzed. It is shown that, with appropriately designed simulations experiments, quasi-linear theory can be quantitatively verified for parameters corresponding to the electron foreshock.

  12. Five Big, Big Five Issues : Rationale, Content, Structure, Status, and Crosscultural Assessment

    NARCIS (Netherlands)

    De Raad, Boele

    1998-01-01

    This article discusses the rationale, content, structure, status, and crosscultural assessment of the Big Five trait factors, focusing on topics of dispute and misunderstanding. Taxonomic restrictions of the original Big Five forerunner, the "Norman Five," are discussed, and criticisms regarding the

  13. Big data challenges

    DEFF Research Database (Denmark)

    Bachlechner, Daniel; Leimbach, Timo

    2016-01-01

    Although reports on big data success stories have been accumulating in the media, most organizations dealing with high-volume, high-velocity and high-variety information assets still face challenges. Only a thorough understanding of these challenges puts organizations into a position in which...... they can make an informed decision for or against big data, and, if the decision is positive, overcome the challenges smoothly. The combination of a series of interviews with leading experts from enterprises, associations and research institutions, and focused literature reviews allowed not only...... framework are also relevant. For large enterprises and startups specialized in big data, it is typically easier to overcome the challenges than it is for other enterprises and public administration bodies....

  14. Big Data and HPC collocation: Using HPC idle resources for Big Data Analytics

    OpenAIRE

    MERCIER , Michael; Glesser , David; Georgiou , Yiannis; Richard , Olivier

    2017-01-01

    International audience; Executing Big Data workloads upon High Performance Computing (HPC) infrastractures has become an attractive way to improve their performances. However, the collocation of HPC and Big Data workloads is not an easy task, mainly because of their core concepts' differences. This paper focuses on the challenges related to the scheduling of both Big Data and HPC workloads on the same computing platform. In classic HPC workloads, the rigidity of jobs tends to create holes in ...

  15. Blue Ocean Thinking

    Science.gov (United States)

    Orem, Donna

    2016-01-01

    This article describes a concept called the "blue ocean thinking strategy," developed by W. Chan Kim and Renée Mauborgne, professors at INSEAD, an international graduate school of business in France. The "blue ocean" thinking strategy considers opportunities to create new markets for services, rather than focusing solely on…

  16. Big Data as Governmentality

    DEFF Research Database (Denmark)

    Flyverbom, Mikkel; Madsen, Anders Koed; Rasche, Andreas

    This paper conceptualizes how large-scale data and algorithms condition and reshape knowledge production when addressing international development challenges. The concept of governmentality and four dimensions of an analytics of government are proposed as a theoretical framework to examine how big...... data is constituted as an aspiration to improve the data and knowledge underpinning development efforts. Based on this framework, we argue that big data’s impact on how relevant problems are governed is enabled by (1) new techniques of visualizing development issues, (2) linking aspects...... shows that big data problematizes selected aspects of traditional ways to collect and analyze data for development (e.g. via household surveys). We also demonstrate that using big data analyses to address development challenges raises a number of questions that can deteriorate its impact....

  17. Boarding to Big data

    Directory of Open Access Journals (Sweden)

    Oana Claudia BRATOSIN

    2016-05-01

    Full Text Available Today Big data is an emerging topic, as the quantity of the information grows exponentially, laying the foundation for its main challenge, the value of the information. The information value is not only defined by the value extraction from huge data sets, as fast and optimal as possible, but also by the value extraction from uncertain and inaccurate data, in an innovative manner using Big data analytics. At this point, the main challenge of the businesses that use Big data tools is to clearly define the scope and the necessary output of the business so that the real value can be gained. This article aims to explain the Big data concept, its various classifications criteria, architecture, as well as the impact in the world wide processes.

  18. Big data - a 21st century science Maginot Line? No-boundary thinking: shifting from the big data paradigm.

    Science.gov (United States)

    Huang, Xiuzhen; Jennings, Steven F; Bruce, Barry; Buchan, Alison; Cai, Liming; Chen, Pengyin; Cramer, Carole L; Guan, Weihua; Hilgert, Uwe Kk; Jiang, Hongmei; Li, Zenglu; McClure, Gail; McMullen, Donald F; Nanduri, Bindu; Perkins, Andy; Rekepalli, Bhanu; Salem, Saeed; Specker, Jennifer; Walker, Karl; Wunsch, Donald; Xiong, Donghai; Zhang, Shuzhong; Zhang, Yu; Zhao, Zhongming; Moore, Jason H

    2015-01-01

    Whether your interests lie in scientific arenas, the corporate world, or in government, you have certainly heard the praises of big data: Big data will give you new insights, allow you to become more efficient, and/or will solve your problems. While big data has had some outstanding successes, many are now beginning to see that it is not the Silver Bullet that it has been touted to be. Here our main concern is the overall impact of big data; the current manifestation of big data is constructing a Maginot Line in science in the 21st century. Big data is not "lots of data" as a phenomena anymore; The big data paradigm is putting the spirit of the Maginot Line into lots of data. Big data overall is disconnecting researchers and science challenges. We propose No-Boundary Thinking (NBT), applying no-boundary thinking in problem defining to address science challenges.

  19. Big Egos in Big Science

    DEFF Research Database (Denmark)

    Andersen, Kristina Vaarst; Jeppesen, Jacob

    In this paper we investigate the micro-mechanisms governing structural evolution and performance of scientific collaboration. Scientific discovery tends not to be lead by so called lone ?stars?, or big egos, but instead by collaboration among groups of researchers, from a multitude of institutions...

  20. Big Data and Big Science

    OpenAIRE

    Di Meglio, Alberto

    2014-01-01

    Brief introduction to the challenges of big data in scientific research based on the work done by the HEP community at CERN and how the CERN openlab promotes collaboration among research institutes and industrial IT companies. Presented at the FutureGov 2014 conference in Singapore.

  1. Blue Emission in Proteins

    OpenAIRE

    Sarkar, Sohini; Sengupta, Abhigyan; Hazra, Partha; Mandal, Pankaj

    2014-01-01

    Recent literatures reported blue-green emission from amyloid fibril as exclusive signature of fibril formation. This unusual visible luminescence is regularly used to monitor fibril growth. Blue-green emission has also been observed in crystalline protein and in solution. However, the origin of this emission is not known exactly. Our spectroscopic study of serum proteins reveals that the blue-green emission is a property of protein monomer. Evidences suggest that semiconductor-like band struc...

  2. Challenges of Big Data Analysis.

    Science.gov (United States)

    Fan, Jianqing; Han, Fang; Liu, Han

    2014-06-01

    Big Data bring new opportunities to modern society and challenges to data scientists. On one hand, Big Data hold great promises for discovering subtle population patterns and heterogeneities that are not possible with small-scale data. On the other hand, the massive sample size and high dimensionality of Big Data introduce unique computational and statistical challenges, including scalability and storage bottleneck, noise accumulation, spurious correlation, incidental endogeneity, and measurement errors. These challenges are distinguished and require new computational and statistical paradigm. This article gives overviews on the salient features of Big Data and how these features impact on paradigm change on statistical and computational methods as well as computing architectures. We also provide various new perspectives on the Big Data analysis and computation. In particular, we emphasize on the viability of the sparsest solution in high-confidence set and point out that exogeneous assumptions in most statistical methods for Big Data can not be validated due to incidental endogeneity. They can lead to wrong statistical inferences and consequently wrong scientific conclusions.

  3. Big data is not a monolith

    CERN Document Server

    Ekbia, Hamid R; Mattioli, Michael

    2016-01-01

    Big data is ubiquitous but heterogeneous. Big data can be used to tally clicks and traffic on web pages, find patterns in stock trades, track consumer preferences, identify linguistic correlations in large corpuses of texts. This book examines big data not as an undifferentiated whole but contextually, investigating the varied challenges posed by big data for health, science, law, commerce, and politics. Taken together, the chapters reveal a complex set of problems, practices, and policies. The advent of big data methodologies has challenged the theory-driven approach to scientific knowledge in favor of a data-driven one. Social media platforms and self-tracking tools change the way we see ourselves and others. The collection of data by corporations and government threatens privacy while promoting transparency. Meanwhile, politicians, policy makers, and ethicists are ill-prepared to deal with big data's ramifications. The contributors look at big data's effect on individuals as it exerts social control throu...

  4. Big universe, big data

    DEFF Research Database (Denmark)

    Kremer, Jan; Stensbo-Smidt, Kristoffer; Gieseke, Fabian Cristian

    2017-01-01

    , modern astronomy requires big data know-how, in particular it demands highly efficient machine learning and image analysis algorithms. But scalability is not the only challenge: Astronomy applications touch several current machine learning research questions, such as learning from biased data and dealing......, and highlight some recent methodological advancements in machine learning and image analysis triggered by astronomical applications....

  5. Poker Player Behavior After Big Wins and Big Losses

    OpenAIRE

    Gary Smith; Michael Levere; Robert Kurtzman

    2009-01-01

    We find that experienced poker players typically change their style of play after winning or losing a big pot--most notably, playing less cautiously after a big loss, evidently hoping for lucky cards that will erase their loss. This finding is consistent with Kahneman and Tversky's (Kahneman, D., A. Tversky. 1979. Prospect theory: An analysis of decision under risk. Econometrica 47(2) 263-292) break-even hypothesis and suggests that when investors incur a large loss, it might be time to take ...

  6. Big Data and Chemical Education

    Science.gov (United States)

    Pence, Harry E.; Williams, Antony J.

    2016-01-01

    The amount of computerized information that organizations collect and process is growing so large that the term Big Data is commonly being used to describe the situation. Accordingly, Big Data is defined by a combination of the Volume, Variety, Velocity, and Veracity of the data being processed. Big Data tools are already having an impact in…

  7. Big data in Finnish financial services

    OpenAIRE

    Laurila, M. (Mikko)

    2017-01-01

    Abstract This thesis aims to explore the concept of big data, and create understanding of big data maturity in the Finnish financial services industry. The research questions of this thesis are “What kind of big data solutions are being implemented in the Finnish financial services sector?” and “Which factors impede faster implementation of big data solutions in the Finnish financial services sector?”. ...

  8. Big data in fashion industry

    Science.gov (United States)

    Jain, S.; Bruniaux, J.; Zeng, X.; Bruniaux, P.

    2017-10-01

    Significant work has been done in the field of big data in last decade. The concept of big data includes analysing voluminous data to extract valuable information. In the fashion world, big data is increasingly playing a part in trend forecasting, analysing consumer behaviour, preference and emotions. The purpose of this paper is to introduce the term fashion data and why it can be considered as big data. It also gives a broad classification of the types of fashion data and briefly defines them. Also, the methodology and working of a system that will use this data is briefly described.

  9. Maximal loads acting on legs of powered roof support unit in longwalls with bumping hazards

    Institute of Scientific and Technical Information of China (English)

    StanislawSzweda

    2001-01-01

    In the article the results of measurements of the resultant force in the legs of a powered roof support unit, caused by a dynamic interaction bf the rock mass, are discussed. The measurements have been taken in the Iongwalls mined with a roof fall, characterized by the highest degree of bumping hazard. It has been stated that the maximal force in the legs Fro, recorded during a dynamic interaction of the rock mass, is proportional to the initial static force in the legs Fst.p Therefore a need for a careful selection of the initial load of the powered roof support, according to the local mining and geological conditions, results from such a statement. Setting the legs with the supporting load exceeding the indispensable value for keeping the direct roof solids in balance, deteriorating the operational parameters of a Iongwall system also has a disadvantageous influence on the value of the force in the legs and the rate of its increase, caused by a dynamic interaction of the rock mass. A correct selection of the initial load causes a decrease in the intensity of a dynamic interaction of the rock mass on powered roof supports, which also has an advanta igeous influence on their life, Simultaneously with the measurements of the resultant force in the legs, the vertical acceleration of the canopy was also recorded. It has enabled to prove that the external dynamic forces may act on the unit both from the roof as well as from the floor. The changes of the force in the legs caused by dynamic phenomena intrinsically created in the roof and changes of the force in the legs caused by blasting explosives in the roof of the working, have been analyzed separately. It has been stated that an increase in the loads of legs, caused by intrinsic phenomena is significantly higher than a force increase in the legs caused by blasting. It means that powered roof supports, to be operated in the workings, where the bumping hazard occurs, will also transmit the loads acting on a unit

  10. Evaluation of Code Blue Implementation Outcomes

    Directory of Open Access Journals (Sweden)

    Bengü Özütürk

    2015-09-01

    Full Text Available Aim: In this study, we aimed to emphasize the importance of Code Blue implementation and to determine deficiencies in this regard. Methods: After obtaining the ethics committee approval, 225 patient’s code blue call data between 2012 and 2014 January were retrospectively analyzed. Age and gender of the patients, date and time of the call and the clinics giving Code Blue, the time needed for the Code Blue team to arrive, the rates of false Code Blue calls, reasons for Code Blue calls and patient outcomes were investigated. Results: A total of 225 patients (149 male, 76 female were evaluated in the study. The mean age of the patients was 54.1 years. 142 (67.2% Code Blue calls occurred after hours and by emergency unit. The mean time for the Code Blue team to arrive was 1.10 minutes. Spontaneous circulation was provided in 137 patients (60.8%; 88 (39.1% died. The most commonly identified possible causes were of cardiac origin. Conclusion: This study showed that Code Blue implementation with a professional team within an efficient and targeted time increase the survival rate. Therefore, we conclude that the application of Code Blue carried out by a trained team is an essential standard in hospitals. (The Medical Bulletin of Haseki 2015; 53:204-8

  11. Big data bioinformatics.

    Science.gov (United States)

    Greene, Casey S; Tan, Jie; Ung, Matthew; Moore, Jason H; Cheng, Chao

    2014-12-01

    Recent technological advances allow for high throughput profiling of biological systems in a cost-efficient manner. The low cost of data generation is leading us to the "big data" era. The availability of big data provides unprecedented opportunities but also raises new challenges for data mining and analysis. In this review, we introduce key concepts in the analysis of big data, including both "machine learning" algorithms as well as "unsupervised" and "supervised" examples of each. We note packages for the R programming language that are available to perform machine learning analyses. In addition to programming based solutions, we review webservers that allow users with limited or no programming background to perform these analyses on large data compendia. © 2014 Wiley Periodicals, Inc.

  12. Changing the personality of a face: Perceived Big Two and Big Five personality factors modeled in real photographs.

    Science.gov (United States)

    Walker, Mirella; Vetter, Thomas

    2016-04-01

    General, spontaneous evaluations of strangers based on their faces have been shown to reflect judgments of these persons' intention and ability to harm. These evaluations can be mapped onto a 2D space defined by the dimensions trustworthiness (intention) and dominance (ability). Here we go beyond general evaluations and focus on more specific personality judgments derived from the Big Two and Big Five personality concepts. In particular, we investigate whether Big Two/Big Five personality judgments can be mapped onto the 2D space defined by the dimensions trustworthiness and dominance. Results indicate that judgments of the Big Two personality dimensions almost perfectly map onto the 2D space. In contrast, at least 3 of the Big Five dimensions (i.e., neuroticism, extraversion, and conscientiousness) go beyond the 2D space, indicating that additional dimensions are necessary to describe more specific face-based personality judgments accurately. Building on this evidence, we model the Big Two/Big Five personality dimensions in real facial photographs. Results from 2 validation studies show that the Big Two/Big Five are perceived reliably across different samples of faces and participants. Moreover, results reveal that participants differentiate reliably between the different Big Two/Big Five dimensions. Importantly, this high level of agreement and differentiation in personality judgments from faces likely creates a subjective reality which may have serious consequences for those being perceived-notably, these consequences ensue because the subjective reality is socially shared, irrespective of the judgments' validity. The methodological approach introduced here might prove useful in various psychological disciplines. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  13. The BigBOSS Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Schelgel, D.; Abdalla, F.; Abraham, T.; Ahn, C.; Allende Prieto, C.; Annis, J.; Aubourg, E.; Azzaro, M.; Bailey, S.; Baltay, C.; Baugh, C.; /APC, Paris /Brookhaven /IRFU, Saclay /Marseille, CPPM /Marseille, CPT /Durham U. / /IEU, Seoul /Fermilab /IAA, Granada /IAC, La Laguna

    2011-01-01

    BigBOSS will obtain observational constraints that will bear on three of the four 'science frontier' questions identified by the Astro2010 Cosmology and Fundamental Phyics Panel of the Decadal Survey: Why is the universe accelerating; what is dark matter and what are the properties of neutrinos? Indeed, the BigBOSS project was recommended for substantial immediate R and D support the PASAG report. The second highest ground-based priority from the Astro2010 Decadal Survey was the creation of a funding line within the NSF to support a 'Mid-Scale Innovations' program, and it used BigBOSS as a 'compelling' example for support. This choice was the result of the Decadal Survey's Program Priorization panels reviewing 29 mid-scale projects and recommending BigBOSS 'very highly'.

  14. Big game hunting practices, meanings, motivations and constraints: a survey of Oregon big game hunters

    Science.gov (United States)

    Suresh K. Shrestha; Robert C. Burns

    2012-01-01

    We conducted a self-administered mail survey in September 2009 with randomly selected Oregon hunters who had purchased big game hunting licenses/tags for the 2008 hunting season. Survey questions explored hunting practices, the meanings of and motivations for big game hunting, the constraints to big game hunting participation, and the effects of age, years of hunting...

  15. Tunable photonic crystals with partial bandgaps from blue phase colloidal crystals and dielectric-doped blue phases.

    Science.gov (United States)

    Stimulak, Mitja; Ravnik, Miha

    2014-09-07

    Blue phase colloidal crystals and dielectric nanoparticle/polymer doped blue phases are demonstrated to combine multiple components with different symmetries in one photonic material, creating a photonic crystal with variable and micro-controllable photonic band structure. In this composite photonic material, one contribution to the band structure is determined by the 3D periodic birefringent orientational profile of the blue phases, whereas the second contribution emerges from the regular array of the colloidal particles or from the dielectric/nanoparticle-doped defect network. Using the planewave expansion method, optical photonic bands of the blue phase I and II colloidal crystals and related nanoparticle/polymer doped blue phases are calculated, and then compared to blue phases with no particles and to face-centred-cubic and body-centred-cubic colloidal crystals in isotropic background. We find opening of local band gaps at particular points of Brillouin zone for blue phase colloidal crystals, where there were none in blue phases without particles or dopants. Particle size and filling fraction of the blue phase defect network are demonstrated as parameters that can directly tune the optical bands and local band gaps. In the blue phase I colloidal crystal with an additionally doped defect network, interestingly, we find an indirect total band gap (with the exception of one point) at the entire edge of SC irreducible zone. Finally, this work demonstrates the role of combining multiple - by symmetry - differently organised components in one photonic crystal material, which offers a novel approach towards tunable soft matter photonic materials.

  16. Google BigQuery analytics

    CERN Document Server

    Tigani, Jordan

    2014-01-01

    How to effectively use BigQuery, avoid common mistakes, and execute sophisticated queries against large datasets Google BigQuery Analytics is the perfect guide for business and data analysts who want the latest tips on running complex queries and writing code to communicate with the BigQuery API. The book uses real-world examples to demonstrate current best practices and techniques, and also explains and demonstrates streaming ingestion, transformation via Hadoop in Google Compute engine, AppEngine datastore integration, and using GViz with Tableau to generate charts of query results. In addit

  17. Big data for dummies

    CERN Document Server

    Hurwitz, Judith; Halper, Fern; Kaufman, Marcia

    2013-01-01

    Find the right big data solution for your business or organization Big data management is one of the major challenges facing business, industry, and not-for-profit organizations. Data sets such as customer transactions for a mega-retailer, weather patterns monitored by meteorologists, or social network activity can quickly outpace the capacity of traditional data management tools. If you need to develop or manage big data solutions, you'll appreciate how these four experts define, explain, and guide you through this new and often confusing concept. You'll learn what it is, why it m

  18. Endogenous estrogen status, but not genistein supplementation, modulates 7,12-dimethylbenz[a]anthracene-induced mutation in the liver cII gene of transgenic big blue rats.

    Science.gov (United States)

    Chen, Tao; Hutts, Robert C; Mei, Nan; Liu, Xiaoli; Bishop, Michelle E; Shelton, Sharon; Manjanatha, Mugimane G; Aidoo, Anane

    2005-06-01

    A growing number of studies suggest that isoflavones found in soybeans have estrogenic activity and may safely alleviate the symptoms of menopause. One of these isoflavones, genistein, is commonly used by postmenopausal women as an alternative to hormone replacement therapy. Although sex hormones have been implicated as an important risk factor for the development of hepatocellular carcinoma, there are limited data on the potential effects of the estrogens, including phytoestrogens, on chemical mutagenesis in liver. Because of the association between mutation induction and the carcinogenesis process, we investigated whether endogenous estrogen and supplemental genistein affect 7,12-dimethylbenz[a]anthracene (DMBA)-induced mutagenesis in rat liver. Intact and ovariectomized female Big Blue rats were treated with 80 mg DMBA/kg body weight. Some of the rats also received a supplement of 1,000 ppm genistein. Sixteen weeks after the carcinogen treatment, the rats were sacrificed, their livers were removed, and mutant frequencies (MFs) and types of mutations were determined in the liver cII gene. DMBA significantly increased the MFs in liver for both the intact and ovariectomized rats. While there was no significant difference in MF between the ovariectomized and intact control animals, the mutation induction by DMBA in the ovariectomized groups was significantly higher than that in the intact groups. Dietary genistein did not alter these responses. Molecular analysis of the mutants showed that DMBA induced chemical-specific types of mutations in the liver cII gene. These results suggest that endogenous ovarian hormones have an inhibitory effect on liver mutagenesis by DMBA, whereas dietary genistein does not modulate spontaneous or DMBA-induced mutagenesis in either intact or ovariectomized rats.

  19. Exploring complex and big data

    Directory of Open Access Journals (Sweden)

    Stefanowski Jerzy

    2017-12-01

    Full Text Available This paper shows how big data analysis opens a range of research and technological problems and calls for new approaches. We start with defining the essential properties of big data and discussing the main types of data involved. We then survey the dedicated solutions for storing and processing big data, including a data lake, virtual integration, and a polystore architecture. Difficulties in managing data quality and provenance are also highlighted. The characteristics of big data imply also specific requirements and challenges for data mining algorithms, which we address as well. The links with related areas, including data streams and deep learning, are discussed. The common theme that naturally emerges from this characterization is complexity. All in all, we consider it to be the truly defining feature of big data (posing particular research and technological challenges, which ultimately seems to be of greater importance than the sheer data volume.

  20. Was there a big bang

    International Nuclear Information System (INIS)

    Narlikar, J.

    1981-01-01

    In discussing the viability of the big-bang model of the Universe relative evidence is examined including the discrepancies in the age of the big-bang Universe, the red shifts of quasars, the microwave background radiation, general theory of relativity aspects such as the change of the gravitational constant with time, and quantum theory considerations. It is felt that the arguments considered show that the big-bang picture is not as soundly established, either theoretically or observationally, as it is usually claimed to be, that the cosmological problem is still wide open and alternatives to the standard big-bang picture should be seriously investigated. (U.K.)

  1. BIG DATA-DRIVEN MARKETING: AN ABSTRACT

    OpenAIRE

    Suoniemi, Samppa; Meyer-Waarden, Lars; Munzel, Andreas

    2017-01-01

    Customer information plays a key role in managing successful relationships with valuable customers. Big data customer analytics use (BD use), i.e., the extent to which customer information derived from big data analytics guides marketing decisions, helps firms better meet customer needs for competitive advantage. This study addresses three research questions: What are the key antecedents of big data customer analytics use? How, and to what extent, does big data customer an...

  2. Big Data Analytics in Medicine and Healthcare.

    Science.gov (United States)

    Ristevski, Blagoj; Chen, Ming

    2018-05-10

    This paper surveys big data with highlighting the big data analytics in medicine and healthcare. Big data characteristics: value, volume, velocity, variety, veracity and variability are described. Big data analytics in medicine and healthcare covers integration and analysis of large amount of complex heterogeneous data such as various - omics data (genomics, epigenomics, transcriptomics, proteomics, metabolomics, interactomics, pharmacogenomics, diseasomics), biomedical data and electronic health records data. We underline the challenging issues about big data privacy and security. Regarding big data characteristics, some directions of using suitable and promising open-source distributed data processing software platform are given.

  3. The trashing of Big Green

    International Nuclear Information System (INIS)

    Felten, E.

    1990-01-01

    The Big Green initiative on California's ballot lost by a margin of 2-to-1. Green measures lost in five other states, shocking ecology-minded groups. According to the postmortem by environmentalists, Big Green was a victim of poor timing and big spending by the opposition. Now its supporters plan to break up the bill and try to pass some provisions in the Legislature

  4. The Big Bang Singularity

    Science.gov (United States)

    Ling, Eric

    The big bang theory is a model of the universe which makes the striking prediction that the universe began a finite amount of time in the past at the so called "Big Bang singularity." We explore the physical and mathematical justification of this surprising result. After laying down the framework of the universe as a spacetime manifold, we combine physical observations with global symmetrical assumptions to deduce the FRW cosmological models which predict a big bang singularity. Next we prove a couple theorems due to Stephen Hawking which show that the big bang singularity exists even if one removes the global symmetrical assumptions. Lastly, we investigate the conditions one needs to impose on a spacetime if one wishes to avoid a singularity. The ideas and concepts used here to study spacetimes are similar to those used to study Riemannian manifolds, therefore we compare and contrast the two geometries throughout.

  5. Reframing Open Big Data

    DEFF Research Database (Denmark)

    Marton, Attila; Avital, Michel; Jensen, Tina Blegind

    2013-01-01

    Recent developments in the techniques and technologies of collecting, sharing and analysing data are challenging the field of information systems (IS) research let alone the boundaries of organizations and the established practices of decision-making. Coined ‘open data’ and ‘big data......’, these developments introduce an unprecedented level of societal and organizational engagement with the potential of computational data to generate new insights and information. Based on the commonalities shared by open data and big data, we develop a research framework that we refer to as open big data (OBD......) by employing the dimensions of ‘order’ and ‘relationality’. We argue that these dimensions offer a viable approach for IS research on open and big data because they address one of the core value propositions of IS; i.e. how to support organizing with computational data. We contrast these dimensions with two...

  6. Medical big data: promise and challenges.

    Science.gov (United States)

    Lee, Choong Ho; Yoon, Hyung-Jin

    2017-03-01

    The concept of big data, commonly characterized by volume, variety, velocity, and veracity, goes far beyond the data type and includes the aspects of data analysis, such as hypothesis-generating, rather than hypothesis-testing. Big data focuses on temporal stability of the association, rather than on causal relationship and underlying probability distribution assumptions are frequently not required. Medical big data as material to be analyzed has various features that are not only distinct from big data of other disciplines, but also distinct from traditional clinical epidemiology. Big data technology has many areas of application in healthcare, such as predictive modeling and clinical decision support, disease or safety surveillance, public health, and research. Big data analytics frequently exploits analytic methods developed in data mining, including classification, clustering, and regression. Medical big data analyses are complicated by many technical issues, such as missing values, curse of dimensionality, and bias control, and share the inherent limitations of observation study, namely the inability to test causality resulting from residual confounding and reverse causation. Recently, propensity score analysis and instrumental variable analysis have been introduced to overcome these limitations, and they have accomplished a great deal. Many challenges, such as the absence of evidence of practical benefits of big data, methodological issues including legal and ethical issues, and clinical integration and utility issues, must be overcome to realize the promise of medical big data as the fuel of a continuous learning healthcare system that will improve patient outcome and reduce waste in areas including nephrology.

  7. Medical big data: promise and challenges

    Directory of Open Access Journals (Sweden)

    Choong Ho Lee

    2017-03-01

    Full Text Available The concept of big data, commonly characterized by volume, variety, velocity, and veracity, goes far beyond the data type and includes the aspects of data analysis, such as hypothesis-generating, rather than hypothesis-testing. Big data focuses on temporal stability of the association, rather than on causal relationship and underlying probability distribution assumptions are frequently not required. Medical big data as material to be analyzed has various features that are not only distinct from big data of other disciplines, but also distinct from traditional clinical epidemiology. Big data technology has many areas of application in healthcare, such as predictive modeling and clinical decision support, disease or safety surveillance, public health, and research. Big data analytics frequently exploits analytic methods developed in data mining, including classification, clustering, and regression. Medical big data analyses are complicated by many technical issues, such as missing values, curse of dimensionality, and bias control, and share the inherent limitations of observation study, namely the inability to test causality resulting from residual confounding and reverse causation. Recently, propensity score analysis and instrumental variable analysis have been introduced to overcome these limitations, and they have accomplished a great deal. Many challenges, such as the absence of evidence of practical benefits of big data, methodological issues including legal and ethical issues, and clinical integration and utility issues, must be overcome to realize the promise of medical big data as the fuel of a continuous learning healthcare system that will improve patient outcome and reduce waste in areas including nephrology.

  8. What is beyond the big five?

    Science.gov (United States)

    Saucier, G; Goldberg, L R

    1998-08-01

    Previous investigators have proposed that various kinds of person-descriptive content--such as differences in attitudes or values, in sheer evaluation, in attractiveness, or in height and girth--are not adequately captured by the Big Five Model. We report on a rather exhaustive search for reliable sources of Big Five-independent variation in data from person-descriptive adjectives. Fifty-three candidate clusters were developed in a college sample using diverse approaches and sources. In a nonstudent adult sample, clusters were evaluated with respect to a minimax criterion: minimum multiple correlation with factors from Big Five markers and maximum reliability. The most clearly Big Five-independent clusters referred to Height, Girth, Religiousness, Employment Status, Youthfulness and Negative Valence (or low-base-rate attributes). Clusters referring to Fashionableness, Sensuality/Seductiveness, Beauty, Masculinity, Frugality, Humor, Wealth, Prejudice, Folksiness, Cunning, and Luck appeared to be potentially beyond the Big Five, although each of these clusters demonstrated Big Five multiple correlations of .30 to .45, and at least one correlation of .20 and over with a Big Five factor. Of all these content areas, Religiousness, Negative Valence, and the various aspects of Attractiveness were found to be represented by a substantial number of distinct, common adjectives. Results suggest directions for supplementing the Big Five when one wishes to extend variable selection outside the domain of personality traits as conventionally defined.

  9. Big Data Analytics and Its Applications

    Directory of Open Access Journals (Sweden)

    Mashooque A. Memon

    2017-10-01

    Full Text Available The term, Big Data, has been authored to refer to the extensive heave of data that can't be managed by traditional data handling methods or techniques. The field of Big Data plays an indispensable role in various fields, such as agriculture, banking, data mining, education, chemistry, finance, cloud computing, marketing, health care stocks. Big data analytics is the method for looking at big data to reveal hidden patterns, incomprehensible relationship and other important data that can be utilize to resolve on enhanced decisions. There has been a perpetually expanding interest for big data because of its fast development and since it covers different areas of applications. Apache Hadoop open source technology created in Java and keeps running on Linux working framework was used. The primary commitment of this exploration is to display an effective and free solution for big data application in a distributed environment, with its advantages and indicating its easy use. Later on, there emerge to be a required for an analytical review of new developments in the big data technology. Healthcare is one of the best concerns of the world. Big data in healthcare imply to electronic health data sets that are identified with patient healthcare and prosperity. Data in the healthcare area is developing past managing limit of the healthcare associations and is relied upon to increment fundamentally in the coming years.

  10. Measuring the Promise of Big Data Syllabi

    Science.gov (United States)

    Friedman, Alon

    2018-01-01

    Growing interest in Big Data is leading industries, academics and governments to accelerate Big Data research. However, how teachers should teach Big Data has not been fully examined. This article suggests criteria for redesigning Big Data syllabi in public and private degree-awarding higher education establishments. The author conducted a survey…

  11. 77 FR 27245 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN

    Science.gov (United States)

    2012-05-09

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N069; FXRS1265030000S3-123-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN AGENCY: Fish and... plan (CCP) and environmental assessment (EA) for Big Stone National Wildlife Refuge (Refuge, NWR) for...

  12. The BigBoss Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Schelgel, D.; Abdalla, F.; Abraham, T.; Ahn, C.; Allende Prieto, C.; Annis, J.; Aubourg, E.; Azzaro, M.; Bailey, S.; Baltay, C.; Baugh, C.; Bebek, C.; Becerril, S.; Blanton, M.; Bolton, A.; Bromley, B.; Cahn, R.; Carton, P.-H.; Cervanted-Cota, J.L.; Chu, Y.; Cortes, M.; /APC, Paris /Brookhaven /IRFU, Saclay /Marseille, CPPM /Marseille, CPT /Durham U. / /IEU, Seoul /Fermilab /IAA, Granada /IAC, La Laguna / /IAC, Mexico / / /Madrid, IFT /Marseille, Lab. Astrophys. / / /New York U. /Valencia U.

    2012-06-07

    BigBOSS is a Stage IV ground-based dark energy experiment to study baryon acoustic oscillations (BAO) and the growth of structure with a wide-area galaxy and quasar redshift survey over 14,000 square degrees. It has been conditionally accepted by NOAO in response to a call for major new instrumentation and a high-impact science program for the 4-m Mayall telescope at Kitt Peak. The BigBOSS instrument is a robotically-actuated, fiber-fed spectrograph capable of taking 5000 simultaneous spectra over a wavelength range from 340 nm to 1060 nm, with a resolution R = {lambda}/{Delta}{lambda} = 3000-4800. Using data from imaging surveys that are already underway, spectroscopic targets are selected that trace the underlying dark matter distribution. In particular, targets include luminous red galaxies (LRGs) up to z = 1.0, extending the BOSS LRG survey in both redshift and survey area. To probe the universe out to even higher redshift, BigBOSS will target bright [OII] emission line galaxies (ELGs) up to z = 1.7. In total, 20 million galaxy redshifts are obtained to measure the BAO feature, trace the matter power spectrum at smaller scales, and detect redshift space distortions. BigBOSS will provide additional constraints on early dark energy and on the curvature of the universe by measuring the Ly-alpha forest in the spectra of over 600,000 2.2 < z < 3.5 quasars. BigBOSS galaxy BAO measurements combined with an analysis of the broadband power, including the Ly-alpha forest in BigBOSS quasar spectra, achieves a FOM of 395 with Planck plus Stage III priors. This FOM is based on conservative assumptions for the analysis of broad band power (k{sub max} = 0.15), and could grow to over 600 if current work allows us to push the analysis to higher wave numbers (k{sub max} = 0.3). BigBOSS will also place constraints on theories of modified gravity and inflation, and will measure the sum of neutrino masses to 0.024 eV accuracy.

  13. Big data and educational research

    OpenAIRE

    Beneito-Montagut, Roser

    2017-01-01

    Big data and data analytics offer the promise to enhance teaching and learning, improve educational research and progress education governance. This chapter aims to contribute to the conceptual and methodological understanding of big data and analytics within educational research. It describes the opportunities and challenges that big data and analytics bring to education as well as critically explore the perils of applying a data driven approach to education. Despite the claimed value of the...

  14. Thick-Big Descriptions

    DEFF Research Database (Denmark)

    Lai, Signe Sophus

    The paper discusses the rewards and challenges of employing commercial audience measurements data – gathered by media industries for profitmaking purposes – in ethnographic research on the Internet in everyday life. It questions claims to the objectivity of big data (Anderson 2008), the assumption...... communication systems, language and behavior appear as texts, outputs, and discourses (data to be ‘found’) – big data then documents things that in earlier research required interviews and observations (data to be ‘made’) (Jensen 2014). However, web-measurement enterprises build audiences according...... to a commercial logic (boyd & Crawford 2011) and is as such directed by motives that call for specific types of sellable user data and specific segmentation strategies. In combining big data and ‘thick descriptions’ (Geertz 1973) scholars need to question how ethnographic fieldwork might map the ‘data not seen...

  15. Big Data's Role in Precision Public Health.

    Science.gov (United States)

    Dolley, Shawn

    2018-01-01

    Precision public health is an emerging practice to more granularly predict and understand public health risks and customize treatments for more specific and homogeneous subpopulations, often using new data, technologies, and methods. Big data is one element that has consistently helped to achieve these goals, through its ability to deliver to practitioners a volume and variety of structured or unstructured data not previously possible. Big data has enabled more widespread and specific research and trials of stratifying and segmenting populations at risk for a variety of health problems. Examples of success using big data are surveyed in surveillance and signal detection, predicting future risk, targeted interventions, and understanding disease. Using novel big data or big data approaches has risks that remain to be resolved. The continued growth in volume and variety of available data, decreased costs of data capture, and emerging computational methods mean big data success will likely be a required pillar of precision public health into the future. This review article aims to identify the precision public health use cases where big data has added value, identify classes of value that big data may bring, and outline the risks inherent in using big data in precision public health efforts.

  16. Big Data, indispensable today

    Directory of Open Access Journals (Sweden)

    Radu-Ioan ENACHE

    2015-10-01

    Full Text Available Big data is and will be used more in the future as a tool for everything that happens both online and offline. Of course , online is a real hobbit, Big Data is found in this medium , offering many advantages , being a real help for all consumers. In this paper we talked about Big Data as being a plus in developing new applications, by gathering useful information about the users and their behaviour.We've also presented the key aspects of real-time monitoring and the architecture principles of this technology. The most important benefit brought to this paper is presented in the cloud section.

  17. Antigravity and the big crunch/big bang transition

    Science.gov (United States)

    Bars, Itzhak; Chen, Shih-Hung; Steinhardt, Paul J.; Turok, Neil

    2012-08-01

    We point out a new phenomenon which seems to be generic in 4d effective theories of scalar fields coupled to Einstein gravity, when applied to cosmology. A lift of such theories to a Weyl-invariant extension allows one to define classical evolution through cosmological singularities unambiguously, and hence construct geodesically complete background spacetimes. An attractor mechanism ensures that, at the level of the effective theory, generic solutions undergo a big crunch/big bang transition by contracting to zero size, passing through a brief antigravity phase, shrinking to zero size again, and re-emerging into an expanding normal gravity phase. The result may be useful for the construction of complete bouncing cosmologies like the cyclic model.

  18. Antigravity and the big crunch/big bang transition

    Energy Technology Data Exchange (ETDEWEB)

    Bars, Itzhak [Department of Physics and Astronomy, University of Southern California, Los Angeles, CA 90089-2535 (United States); Chen, Shih-Hung [Perimeter Institute for Theoretical Physics, Waterloo, ON N2L 2Y5 (Canada); Department of Physics and School of Earth and Space Exploration, Arizona State University, Tempe, AZ 85287-1404 (United States); Steinhardt, Paul J., E-mail: steinh@princeton.edu [Department of Physics and Princeton Center for Theoretical Physics, Princeton University, Princeton, NJ 08544 (United States); Turok, Neil [Perimeter Institute for Theoretical Physics, Waterloo, ON N2L 2Y5 (Canada)

    2012-08-29

    We point out a new phenomenon which seems to be generic in 4d effective theories of scalar fields coupled to Einstein gravity, when applied to cosmology. A lift of such theories to a Weyl-invariant extension allows one to define classical evolution through cosmological singularities unambiguously, and hence construct geodesically complete background spacetimes. An attractor mechanism ensures that, at the level of the effective theory, generic solutions undergo a big crunch/big bang transition by contracting to zero size, passing through a brief antigravity phase, shrinking to zero size again, and re-emerging into an expanding normal gravity phase. The result may be useful for the construction of complete bouncing cosmologies like the cyclic model.

  19. Antigravity and the big crunch/big bang transition

    International Nuclear Information System (INIS)

    Bars, Itzhak; Chen, Shih-Hung; Steinhardt, Paul J.; Turok, Neil

    2012-01-01

    We point out a new phenomenon which seems to be generic in 4d effective theories of scalar fields coupled to Einstein gravity, when applied to cosmology. A lift of such theories to a Weyl-invariant extension allows one to define classical evolution through cosmological singularities unambiguously, and hence construct geodesically complete background spacetimes. An attractor mechanism ensures that, at the level of the effective theory, generic solutions undergo a big crunch/big bang transition by contracting to zero size, passing through a brief antigravity phase, shrinking to zero size again, and re-emerging into an expanding normal gravity phase. The result may be useful for the construction of complete bouncing cosmologies like the cyclic model.

  20. Big data: een zoektocht naar instituties

    NARCIS (Netherlands)

    van der Voort, H.G.; Crompvoets, J

    2016-01-01

    Big data is a well-known phenomenon, even a buzzword nowadays. It refers to an abundance of data and new possibilities to process and use them. Big data is subject of many publications. Some pay attention to the many possibilities of big data, others warn us for their consequences. This special

  1. Data, Data, Data : Big, Linked & Open

    NARCIS (Netherlands)

    Folmer, E.J.A.; Krukkert, D.; Eckartz, S.M.

    2013-01-01

    De gehele business en IT-wereld praat op dit moment over Big Data, een trend die medio 2013 Cloud Computing is gepasseerd (op basis van Google Trends). Ook beleidsmakers houden zich actief bezig met Big Data. Neelie Kroes, vice-president van de Europese Commissie, spreekt over de ‘Big Data

  2. "Blue-Collar Blues" uurib töösuhteid uutes oludes / Janar Ala

    Index Scriptorium Estoniae

    Ala, Janar, 1979-

    2009-01-01

    Tööproblemaatikat käsitlev näitus "Blue-Collar Blues" Tallinna Kunstihoones ja Tallinna Kunstihoone galeriis 31. jaanuarini 2010, kuraator Anders Härm. Lähemalt belgia-mehhiko kunstniku Francis Alys'e videost, austria kunstniku Oliver Ressleri ning venetsueela-saksa politoloogi Dario Azzelini videost "Viis tehast. Tööliste kontroll Venezuelas"

  3. The spectrum of dermatoscopic patterns in blue nevi.

    Science.gov (United States)

    Di Cesare, Antonella; Sera, Francesco; Gulia, Andrea; Coletti, Gino; Micantonio, Tamara; Fargnoli, Maria Concetta; Peris, Ketty

    2012-08-01

    Blue nevi are congenital or acquired, dermal dendritic melanocytic proliferations that can simulate melanocytic and nonmelanocytic lesions including melanoma, cutaneous metastasis of melanoma, Spitz/Reed nevi, and basal cell carcinoma. We sought to investigate global and local dermatoscopic patterns of blue nevi compared with melanomas and basal cell carcinomas. We retrospectively analyzed global and local features in 95 dermatoscopic images of blue nevi and in 190 melanomas and basal cell carcinomas that were selected as control lesions on the basis of similar pigmentation. Lesion pigmentation was classified as monochromatic, dichromatic, or multichromatic. A global pattern characterized by homogeneous pigmentation was observed in all of 95 (100%) blue nevi. Eighty of 95 (84.2%) blue nevi presented a homogeneous pattern consisting of one color (blue, black, or brown) or two colors (blue-brown, blue-gray, or blue-black). Fifteen of 95 (15.8%) blue nevi had a multichromatic (blue, gray, black, brown, and/or red) pigmentation. In all, 47 of 95 (49.5%) blue nevi were characterized by pigmentation in the absence of pigment network or any other local dermatoscopic features. And 48 of 95 (50.5%) blue nevi showed local dermatoscopic patterns including whitish scarlike depigmentation, dots/globules, vascular pattern, streaks, and networklike pattern. The study was retrospective and involved only Caucasian people of Italian origin. The characteristic feature of blue nevi is a homogeneous pigmentation that is blue, blue-gray, blue-brown, or blue-black. We showed that a wide spectrum of local dermatoscopic features (whitish scarlike depigmentation, dots/globules, peripheral streaks or vessels) may also be present. In such cases, clinical and dermatoscopic distinction from melanoma or nonmelanocytic lesions may be difficult or impossible, and surgical excision is necessary. Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  4. Methods and tools for big data visualization

    OpenAIRE

    Zubova, Jelena; Kurasova, Olga

    2015-01-01

    In this paper, methods and tools for big data visualization have been investigated. Challenges faced by the big data analysis and visualization have been identified. Technologies for big data analysis have been discussed. A review of methods and tools for big data visualization has been done. Functionalities of the tools have been demonstrated by examples in order to highlight their advantages and disadvantages.

  5. The Blue Coma: The Role of Methylene Blue in Unexplained Coma After Cardiac Surgery.

    Science.gov (United States)

    Martino, Enrico Antonio; Winterton, Dario; Nardelli, Pasquale; Pasin, Laura; Calabrò, Maria Grazia; Bove, Tiziana; Fanelli, Giovanna; Zangrillo, Alberto; Landoni, Giovanni

    2016-04-01

    Methylene blue commonly is used as a dye or an antidote, but also can be used off label as a vasopressor. Serotonin toxicity is a potentially lethal and often misdiagnosed condition that can result from drug interaction. Mild serotonin toxicity previously was reported in settings in which methylene blue was used as a dye. The authors report 3 cases of life-threatening serotonin toxicity in patients undergoing chronic selective serotonin reuptake inhibitor (SSRI) therapy who also underwent cardiac surgery and received methylene blue to treat vasoplegic syndrome. An observational study. A cardiothoracic intensive care unit (ICU) in a teaching hospital. Three patients who received methylene blue after cardiac surgery, later discovered to be undergoing chronic SSRI therapy. None. All 3 patients received high doses of fentanyl during general anesthesia. They all developed vasoplegic syndrome and consequently were given methylene blue in the ICU. All 3 patients developed serotonin toxicity, including coma, after this administration and diagnostic tests were negative for acute intracranial pathology. Coma lasted between 1 and 5 days. Two patients were discharged from the ICU shortly after awakening, whereas the third patient experienced a complicated postoperative course for concomitant refractory low-cardiac-output syndrome. Patients undergoing chronic SSRI therapy should not be administered methylene blue to treat vasoplegic syndrome. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Big data analytics methods and applications

    CERN Document Server

    Rao, BLS; Rao, SB

    2016-01-01

    This book has a collection of articles written by Big Data experts to describe some of the cutting-edge methods and applications from their respective areas of interest, and provides the reader with a detailed overview of the field of Big Data Analytics as it is practiced today. The chapters cover technical aspects of key areas that generate and use Big Data such as management and finance; medicine and healthcare; genome, cytome and microbiome; graphs and networks; Internet of Things; Big Data standards; bench-marking of systems; and others. In addition to different applications, key algorithmic approaches such as graph partitioning, clustering and finite mixture modelling of high-dimensional data are also covered. The varied collection of themes in this volume introduces the reader to the richness of the emerging field of Big Data Analytics.

  7. The Big bang and the Quantum

    Science.gov (United States)

    Ashtekar, Abhay

    2010-06-01

    General relativity predicts that space-time comes to an end and physics comes to a halt at the big-bang. Recent developments in loop quantum cosmology have shown that these predictions cannot be trusted. Quantum geometry effects can resolve singularities, thereby opening new vistas. Examples are: The big bang is replaced by a quantum bounce; the `horizon problem' disappears; immediately after the big bounce, there is a super-inflationary phase with its own phenomenological ramifications; and, in presence of a standard inflation potential, initial conditions are naturally set for a long, slow roll inflation independently of what happens in the pre-big bang branch. As in my talk at the conference, I will first discuss the foundational issues and then the implications of the new Planck scale physics near the Big Bang.

  8. Big Bang baryosynthesis

    International Nuclear Information System (INIS)

    Turner, M.S.; Chicago Univ., IL

    1983-01-01

    In these lectures I briefly review Big Bang baryosynthesis. In the first lecture I discuss the evidence which exists for the BAU, the failure of non-GUT symmetrical cosmologies, the qualitative picture of baryosynthesis, and numerical results of detailed baryosynthesis calculations. In the second lecture I discuss the requisite CP violation in some detail, further the statistical mechanics of baryosynthesis, possible complications to the simplest scenario, and one cosmological implication of Big Bang baryosynthesis. (orig./HSI)

  9. Exploiting big data for critical care research.

    Science.gov (United States)

    Docherty, Annemarie B; Lone, Nazir I

    2015-10-01

    Over recent years the digitalization, collection and storage of vast quantities of data, in combination with advances in data science, has opened up a new era of big data. In this review, we define big data, identify examples of critical care research using big data, discuss the limitations and ethical concerns of using these large datasets and finally consider scope for future research. Big data refers to datasets whose size, complexity and dynamic nature are beyond the scope of traditional data collection and analysis methods. The potential benefits to critical care are significant, with faster progress in improving health and better value for money. Although not replacing clinical trials, big data can improve their design and advance the field of precision medicine. However, there are limitations to analysing big data using observational methods. In addition, there are ethical concerns regarding maintaining confidentiality of patients who contribute to these datasets. Big data have the potential to improve medical care and reduce costs, both by individualizing medicine, and bringing together multiple sources of data about individual patients. As big data become increasingly mainstream, it will be important to maintain public confidence by safeguarding data security, governance and confidentiality.

  10. Empathy and the Big Five

    OpenAIRE

    Paulus, Christoph

    2016-01-01

    Del Barrio et al. (2004) haben vor mehr als 10 Jahren versucht, eine direkte Beziehung zwischen Empathie und den Big Five herzustellen. Im Mittel hatten in ihrer Stichprobe Frauen höhere Werte in der Empathie und auf den Big Five-Faktoren mit Ausnahme des Faktors Neurotizismus. Zusammenhänge zu Empathie fanden sie in den Bereichen Offenheit, Verträglichkeit, Gewissenhaftigkeit und Extraversion. In unseren Daten besitzen Frauen sowohl in der Empathie als auch den Big Five signifikant höhere We...

  11. Big domains are novel Ca²+-binding modules: evidences from big domains of Leptospira immunoglobulin-like (Lig) proteins.

    Science.gov (United States)

    Raman, Rajeev; Rajanikanth, V; Palaniappan, Raghavan U M; Lin, Yi-Pin; He, Hongxuan; McDonough, Sean P; Sharma, Yogendra; Chang, Yung-Fu

    2010-12-29

    Many bacterial surface exposed proteins mediate the host-pathogen interaction more effectively in the presence of Ca²+. Leptospiral immunoglobulin-like (Lig) proteins, LigA and LigB, are surface exposed proteins containing Bacterial immunoglobulin like (Big) domains. The function of proteins which contain Big fold is not known. Based on the possible similarities of immunoglobulin and βγ-crystallin folds, we here explore the important question whether Ca²+ binds to a Big domains, which would provide a novel functional role of the proteins containing Big fold. We selected six individual Big domains for this study (three from the conserved part of LigA and LigB, denoted as Lig A3, Lig A4, and LigBCon5; two from the variable region of LigA, i.e., 9(th) (Lig A9) and 10(th) repeats (Lig A10); and one from the variable region of LigB, i.e., LigBCen2. We have also studied the conserved region covering the three and six repeats (LigBCon1-3 and LigCon). All these proteins bind the calcium-mimic dye Stains-all. All the selected four domains bind Ca²+ with dissociation constants of 2-4 µM. Lig A9 and Lig A10 domains fold well with moderate thermal stability, have β-sheet conformation and form homodimers. Fluorescence spectra of Big domains show a specific doublet (at 317 and 330 nm), probably due to Trp interaction with a Phe residue. Equilibrium unfolding of selected Big domains is similar and follows a two-state model, suggesting the similarity in their fold. We demonstrate that the Lig are Ca²+-binding proteins, with Big domains harbouring the binding motif. We conclude that despite differences in sequence, a Big motif binds Ca²+. This work thus sets up a strong possibility for classifying the proteins containing Big domains as a novel family of Ca²+-binding proteins. Since Big domain is a part of many proteins in bacterial kingdom, we suggest a possible function these proteins via Ca²+ binding.

  12. Investigation Of The Effects Of Reflow Profile Parameters On Lead-free Solder Bump Volumes And Joint Integrity

    Science.gov (United States)

    Amalu, E. H.; Lui, Y. T.; Ekere, N. N.; Bhatti, R. S.; Takyi, G.

    2011-01-01

    The electronics manufacturing industry was quick to adopt and use the Surface Mount Technology (SMT) assembly technique on realization of its huge potentials in achieving smaller, lighter and low cost product implementations. Increasing global customer demand for miniaturized electronic products is a key driver in the design, development and wide application of high-density area array package format. Electronic components and their associated solder joints have reduced in size as the miniaturization trend in packaging continues to be challenged by printing through very small stencil apertures required for fine pitch flip-chip applications. At very narrow aperture sizes, solder paste rheology becomes crucial for consistent paste withdrawal. The deposition of consistent volume of solder from pad-to-pad is fundamental to minimizing surface mount assembly defects. This study investigates the relationship between volume of solder paste deposit (VSPD) and the volume of solder bump formed (VSBF) after reflow, and the effect of reflow profile parameters on lead-free solder bump formation and the associated solder joint integrity. The study uses a fractional factorial design (FFD) of 24-1 Ramp-Soak-Spike reflow profile, with all main effects and two-way interactions estimable to determine the optimal factorial combination. The results from the study show that the percentage change in the VSPD depends on the combination of the process parameters and reliability issues could become critical as the size of solder joints soldered on the same board assembly vary greatly. Mathematical models describe the relationships among VSPD, VSBF and theoretical volume of solder paste. Some factors have main effects across the volumes and a number of interactions exist among them. These results would be useful for R&D personnel in designing and implementing newer applications with finer-pitch interconnect.

  13. Why Blue-Collar Blacks Help Less

    OpenAIRE

    Smith, Sandra Susan; Young, Kara Alexis

    2013-01-01

    Why are blue-collar blacks less likely to help jobseekers than jobholders from other ethnoracial groups or even than more affluent blacks? Drawing from in-depth, semi-structured interviews with 97 black and Latino workers at one large, public sector employer, we find that blue-collar black workers both helped less proactively and rejected more requests for assistance than did blue-collar Latino and white-collar black workers. We attribute blue-collar blacks’ more passive engagement to their...

  14. Semantic Web Technologies and Big Data Infrastructures: SPARQL Federated Querying of Heterogeneous Big Data Stores

    OpenAIRE

    Konstantopoulos, Stasinos; Charalambidis, Angelos; Mouchakis, Giannis; Troumpoukis, Antonis; Jakobitsch, Jürgen; Karkaletsis, Vangelis

    2016-01-01

    The ability to cross-link large scale data with each other and with structured Semantic Web data, and the ability to uniformly process Semantic Web and other data adds value to both the Semantic Web and to the Big Data community. This paper presents work in progress towards integrating Big Data infrastructures with Semantic Web technologies, allowing for the cross-linking and uniform retrieval of data stored in both Big Data infrastructures and Semantic Web data. The technical challenges invo...

  15. Quantum fields in a big-crunch-big-bang spacetime

    International Nuclear Information System (INIS)

    Tolley, Andrew J.; Turok, Neil

    2002-01-01

    We consider quantum field theory on a spacetime representing the big-crunch-big-bang transition postulated in ekpyrotic or cyclic cosmologies. We show via several independent methods that an essentially unique matching rule holds connecting the incoming state, in which a single extra dimension shrinks to zero, to the outgoing state in which it reexpands at the same rate. For free fields in our construction there is no particle production from the incoming adiabatic vacuum. When interactions are included the particle production for fixed external momentum is finite at the tree level. We discuss a formal correspondence between our construction and quantum field theory on de Sitter spacetime

  16. Turning big bang into big bounce: II. Quantum dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Malkiewicz, Przemyslaw; Piechocki, Wlodzimierz, E-mail: pmalk@fuw.edu.p, E-mail: piech@fuw.edu.p [Theoretical Physics Department, Institute for Nuclear Studies, Hoza 69, 00-681 Warsaw (Poland)

    2010-11-21

    We analyze the big bounce transition of the quantum Friedmann-Robertson-Walker model in the setting of the nonstandard loop quantum cosmology (LQC). Elementary observables are used to quantize composite observables. The spectrum of the energy density operator is bounded and continuous. The spectrum of the volume operator is bounded from below and discrete. It has equally distant levels defining a quantum of the volume. The discreteness may imply a foamy structure of spacetime at a semiclassical level which may be detected in astro-cosmo observations. The nonstandard LQC method has a free parameter that should be fixed in some way to specify the big bounce transition.

  17. Scaling Big Data Cleansing

    KAUST Repository

    Khayyat, Zuhair

    2017-07-31

    Data cleansing approaches have usually focused on detecting and fixing errors with little attention to big data scaling. This presents a serious impediment since identify- ing and repairing dirty data often involves processing huge input datasets, handling sophisticated error discovery approaches and managing huge arbitrary errors. With large datasets, error detection becomes overly expensive and complicated especially when considering user-defined functions. Furthermore, a distinctive algorithm is de- sired to optimize inequality joins in sophisticated error discovery rather than na ̈ıvely parallelizing them. Also, when repairing large errors, their skewed distribution may obstruct effective error repairs. In this dissertation, I present solutions to overcome the above three problems in scaling data cleansing. First, I present BigDansing as a general system to tackle efficiency, scalability, and ease-of-use issues in data cleansing for Big Data. It automatically parallelizes the user’s code on top of general-purpose distributed platforms. Its programming inter- face allows users to express data quality rules independently from the requirements of parallel and distributed environments. Without sacrificing their quality, BigDans- ing also enables parallel execution of serial repair algorithms by exploiting the graph representation of discovered errors. The experimental results show that BigDansing outperforms existing baselines up to more than two orders of magnitude. Although BigDansing scales cleansing jobs, it still lacks the ability to handle sophisticated error discovery requiring inequality joins. Therefore, I developed IEJoin as an algorithm for fast inequality joins. It is based on sorted arrays and space efficient bit-arrays to reduce the problem’s search space. By comparing IEJoin against well- known optimizations, I show that it is more scalable, and several orders of magnitude faster. BigDansing depends on vertex-centric graph systems, i.e., Pregel

  18. The ethics of big data in big agriculture

    Directory of Open Access Journals (Sweden)

    Isabelle M. Carbonell

    2016-03-01

    Full Text Available This paper examines the ethics of big data in agriculture, focusing on the power asymmetry between farmers and large agribusinesses like Monsanto. Following the recent purchase of Climate Corp., Monsanto is currently the most prominent biotech agribusiness to buy into big data. With wireless sensors on tractors monitoring or dictating every decision a farmer makes, Monsanto can now aggregate large quantities of previously proprietary farming data, enabling a privileged position with unique insights on a field-by-field basis into a third or more of the US farmland. This power asymmetry may be rebalanced through open-sourced data, and publicly-funded data analytic tools which rival Climate Corp. in complexity and innovation for use in the public domain.

  19. Homogeneous and isotropic big rips?

    CERN Document Server

    Giovannini, Massimo

    2005-01-01

    We investigate the way big rips are approached in a fully inhomogeneous description of the space-time geometry. If the pressure and energy densities are connected by a (supernegative) barotropic index, the spatial gradients and the anisotropic expansion decay as the big rip is approached. This behaviour is contrasted with the usual big-bang singularities. A similar analysis is performed in the case of sudden (quiescent) singularities and it is argued that the spatial gradients may well be non-negligible in the vicinity of pressure singularities.

  20. Rate Change Big Bang Theory

    Science.gov (United States)

    Strickland, Ken

    2013-04-01

    The Rate Change Big Bang Theory redefines the birth of the universe with a dramatic shift in energy direction and a new vision of the first moments. With rate change graph technology (RCGT) we can look back 13.7 billion years and experience every step of the big bang through geometrical intersection technology. The analysis of the Big Bang includes a visualization of the first objects, their properties, the astounding event that created space and time as well as a solution to the mystery of anti-matter.

  1. Intelligent Test Mechanism Design of Worn Big Gear

    Directory of Open Access Journals (Sweden)

    Hong-Yu LIU

    2014-10-01

    Full Text Available With the continuous development of national economy, big gear was widely applied in metallurgy and mine domains. So, big gear plays an important role in above domains. In practical production, big gear abrasion and breach take place often. It affects normal production and causes unnecessary economic loss. A kind of intelligent test method was put forward on worn big gear mainly aimed at the big gear restriction conditions of high production cost, long production cycle and high- intensity artificial repair welding work. The measure equations transformations were made on involute straight gear. Original polar coordinate equations were transformed into rectangular coordinate equations. Big gear abrasion measure principle was introduced. Detection principle diagram was given. Detection route realization method was introduced. OADM12 laser sensor was selected. Detection on big gear abrasion area was realized by detection mechanism. Tested data of unworn gear and worn gear were led in designed calculation program written by Visual Basic language. Big gear abrasion quantity can be obtained. It provides a feasible method for intelligent test and intelligent repair welding on worn big gear.

  2. [Big data in medicine and healthcare].

    Science.gov (United States)

    Rüping, Stefan

    2015-08-01

    Healthcare is one of the business fields with the highest Big Data potential. According to the prevailing definition, Big Data refers to the fact that data today is often too large and heterogeneous and changes too quickly to be stored, processed, and transformed into value by previous technologies. The technological trends drive Big Data: business processes are more and more executed electronically, consumers produce more and more data themselves - e.g. in social networks - and finally ever increasing digitalization. Currently, several new trends towards new data sources and innovative data analysis appear in medicine and healthcare. From the research perspective, omics-research is one clear Big Data topic. In practice, the electronic health records, free open data and the "quantified self" offer new perspectives for data analytics. Regarding analytics, significant advances have been made in the information extraction from text data, which unlocks a lot of data from clinical documentation for analytics purposes. At the same time, medicine and healthcare is lagging behind in the adoption of Big Data approaches. This can be traced to particular problems regarding data complexity and organizational, legal, and ethical challenges. The growing uptake of Big Data in general and first best-practice examples in medicine and healthcare in particular, indicate that innovative solutions will be coming. This paper gives an overview of the potentials of Big Data in medicine and healthcare.

  3. From Big Data to Big Business

    DEFF Research Database (Denmark)

    Lund Pedersen, Carsten

    2017-01-01

    Idea in Brief: Problem: There is an enormous profit potential for manufacturing firms in big data, but one of the key barriers to obtaining data-driven growth is the lack of knowledge about which capabilities are needed to extract value and profit from data. Solution: We (BDBB research group at C...

  4. Raman analysis of cobalt blue pigment in blue and white porcelain: A reassessment

    Science.gov (United States)

    Jiang, Xiaochenyang; Ma, Yanying; Chen, Yue; Li, Yuanqiu; Ma, Qinglin; Zhang, Zhaoxia; Wang, Changsui; Yang, Yimin

    2018-02-01

    Cobalt blue is a famous pigment in human history. In the past decade it is widely reported that the cobalt aluminate has been detected in ancient ceramics as blue colorant in glaze, yet the acquired Raman spectra are incredibly different from that of synthesised references, necessitating a reassessment of such contradictory scenario with more accurate analytic strategies. In this study, micro-Raman spectroscopy (MRS) and scanning electron microscopy (SEM) in association with energy dispersive spectrometry (EDS) were performed on under-glaze cobalt pigments from one submerged blue and white porcelain shard dated from Wanli reign (1573-1620 CE) of Ming dynasty (1365-1644 CE) excavated at Nan'ao I shipwreck off the southern coast of China. The micro-structural inspection reveals that the pigment particles have characteristics of small account, tiny size, heterogeneously distribution, and more importantly, been completely enwrapped by well-developed anorthite crystals in the glaze, indicating that the signals recorded in previous publications are probably not from cobalt pigments themselves but from outside thickset anorthite shell. The further spectromicroscopic analyses confirm this presumption when the accurate spectra of cobalt aluminate pigment and surrounding anorthite were obtained separately with precise optical positioning. Accordingly, we reassess and clarify the previous Raman studies dedicated to cobalt blue pigment in ancient ceramics, e.g. cobalt blue in celadon glaze, and in turn demonstrate the superiority and necessity of coupling spectroscopic analysis with corresponding structure observation, especially in the characterization of pigments from complicated physico-chemical environment like antiquities. Thus, this study promotes a better understanding of Raman spectroscopy study of cobalt blue pigments in art and archaeology field.

  5. Making big sense from big data in toxicology by read-across.

    Science.gov (United States)

    Hartung, Thomas

    2016-01-01

    Modern information technologies have made big data available in safety sciences, i.e., extremely large data sets that may be analyzed only computationally to reveal patterns, trends and associations. This happens by (1) compilation of large sets of existing data, e.g., as a result of the European REACH regulation, (2) the use of omics technologies and (3) systematic robotized testing in a high-throughput manner. All three approaches and some other high-content technologies leave us with big data--the challenge is now to make big sense of these data. Read-across, i.e., the local similarity-based intrapolation of properties, is gaining momentum with increasing data availability and consensus on how to process and report it. It is predominantly applied to in vivo test data as a gap-filling approach, but can similarly complement other incomplete datasets. Big data are first of all repositories for finding similar substances and ensure that the available data is fully exploited. High-content and high-throughput approaches similarly require focusing on clusters, in this case formed by underlying mechanisms such as pathways of toxicity. The closely connected properties, i.e., structural and biological similarity, create the confidence needed for predictions of toxic properties. Here, a new web-based tool under development called REACH-across, which aims to support and automate structure-based read-across, is presented among others.

  6. [Big data in official statistics].

    Science.gov (United States)

    Zwick, Markus

    2015-08-01

    The concept of "big data" stands to change the face of official statistics over the coming years, having an impact on almost all aspects of data production. The tasks of future statisticians will not necessarily be to produce new data, but rather to identify and make use of existing data to adequately describe social and economic phenomena. Until big data can be used correctly in official statistics, a lot of questions need to be answered and problems solved: the quality of data, data protection, privacy, and the sustainable availability are some of the more pressing issues to be addressed. The essential skills of official statisticians will undoubtedly change, and this implies a number of challenges to be faced by statistical education systems, in universities, and inside the statistical offices. The national statistical offices of the European Union have concluded a concrete strategy for exploring the possibilities of big data for official statistics, by means of the Big Data Roadmap and Action Plan 1.0. This is an important first step and will have a significant influence on implementing the concept of big data inside the statistical offices of Germany.

  7. Big-Leaf Mahogany on CITES Appendix II: Big Challenge, Big Opportunity

    Science.gov (United States)

    JAMES GROGAN; PAULO BARRETO

    2005-01-01

    On 15 November 2003, big-leaf mahogany (Swietenia macrophylla King, Meliaceae), the most valuable widely traded Neotropical timber tree, gained strengthened regulatory protection from its listing on Appendix II of the Convention on International Trade in Endangered Species ofWild Fauna and Flora (CITES). CITES is a United Nations-chartered agreement signed by 164...

  8. Big Data as Information Barrier

    Directory of Open Access Journals (Sweden)

    Victor Ya. Tsvetkov

    2014-07-01

    Full Text Available The article covers analysis of ‘Big Data’ which has been discussed over last 10 years. The reasons and factors for the issue are revealed. It has proved that the factors creating ‘Big Data’ issue has existed for quite a long time, and from time to time, would cause the informational barriers. Such barriers were successfully overcome through the science and technologies. The conducted analysis refers the “Big Data” issue to a form of informative barrier. This issue may be solved correctly and encourages development of scientific and calculating methods.

  9. Big Data in Space Science

    OpenAIRE

    Barmby, Pauline

    2018-01-01

    It seems like “big data” is everywhere these days. In planetary science and astronomy, we’ve been dealing with large datasets for a long time. So how “big” is our data? How does it compare to the big data that a bank or an airline might have? What new tools do we need to analyze big datasets, and how can we make better use of existing tools? What kinds of science problems can we address with these? I’ll address these questions with examples including ESA’s Gaia mission, ...

  10. Blue Creek Winter Range: Wildlife Mitigation Project. Final environmental assessment

    International Nuclear Information System (INIS)

    1994-11-01

    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Agreement pertaining to the Blue Creek Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Spokane Tribe, Upper Columbia United Tribes, and the Bureau of Indian Affairs (BIA). If fully implemented, the proposed action would allow the sponsors to protect and enhance 2,631 habitat units of big game winter range and riparian shrub habitat on 2,185 hectares (5,400 acres) of Spokane Tribal trust lands, and to conduct long term wildlife management activities within the Spokane Indian Reservation project area. This Final Environmental Assessment (EA) examines the potential environmental effects of securing land and conducting wildlife habitat enhancement and long term management activities within the boundaries of the Spokane Indian Reservation. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat adversely affected by the construction of Grand Coulee Dam and its reservoir

  11. Big Data in Medicine is Driving Big Changes

    Science.gov (United States)

    Verspoor, K.

    2014-01-01

    Summary Objectives To summarise current research that takes advantage of “Big Data” in health and biomedical informatics applications. Methods Survey of trends in this work, and exploration of literature describing how large-scale structured and unstructured data sources are being used to support applications from clinical decision making and health policy, to drug design and pharmacovigilance, and further to systems biology and genetics. Results The survey highlights ongoing development of powerful new methods for turning that large-scale, and often complex, data into information that provides new insights into human health, in a range of different areas. Consideration of this body of work identifies several important paradigm shifts that are facilitated by Big Data resources and methods: in clinical and translational research, from hypothesis-driven research to data-driven research, and in medicine, from evidence-based practice to practice-based evidence. Conclusions The increasing scale and availability of large quantities of health data require strategies for data management, data linkage, and data integration beyond the limits of many existing information systems, and substantial effort is underway to meet those needs. As our ability to make sense of that data improves, the value of the data will continue to increase. Health systems, genetics and genomics, population and public health; all areas of biomedicine stand to benefit from Big Data and the associated technologies. PMID:25123716

  12. Main Issues in Big Data Security

    Directory of Open Access Journals (Sweden)

    Julio Moreno

    2016-09-01

    Full Text Available Data is currently one of the most important assets for companies in every field. The continuous growth in the importance and volume of data has created a new problem: it cannot be handled by traditional analysis techniques. This problem was, therefore, solved through the creation of a new paradigm: Big Data. However, Big Data originated new issues related not only to the volume or the variety of the data, but also to data security and privacy. In order to obtain a full perspective of the problem, we decided to carry out an investigation with the objective of highlighting the main issues regarding Big Data security, and also the solutions proposed by the scientific community to solve them. In this paper, we explain the results obtained after applying a systematic mapping study to security in the Big Data ecosystem. It is almost impossible to carry out detailed research into the entire topic of security, and the outcome of this research is, therefore, a big picture of the main problems related to security in a Big Data system, along with the principal solutions to them proposed by the research community.

  13. Polyamines modulate carcinogen-induced mutagenesis in vivo.

    Science.gov (United States)

    Wallon, U Margaretha; O'Brien, Thomas G

    2005-01-01

    Elevated polyamine levels as a consequence of targeted overexpression of ornithine decarboxylase (ODC) to murine skin enhance susceptibility to tumorigenesis in this tissue. A possible mechanism for the enhanced susceptibility phenotype is an increased sensitivity of tissues with elevated polyamine levels to the mutagenic action of carcinogens. To test this hypothesis, a transgenic mouse model containing the Big Blue transgene and also expressing a K6/ODC transgene was developed. Incorporation of the K6/ODC transgene into the Big Blue model did not affect the spontaneous lacI mutant frequency in either skin or epidermis of the double-transgenic mice. After skin treatment with single doses of either 7,12-dimethylbenz[a]anthracene or N-methyl-N'-nitro-N-nitrosoguanidine, however, the mutant frequency was significantly increased in the skin of double-transgenic Big Blue;K6/ODC mice compared to Big Blue controls. The increases in mutant frequency were clearly due to ODC transgene activity, since treatment of mice with the ODC inhibitor, alpha-difluoromethylornithine, completely abolished the difference in mutant frequencies between double-transgenic and Big Blue mice. These results demonstrate that intracellular polyamine levels modulate mutation induction following carcinogen exposure. 2004 Wiley-Liss, Inc.

  14. Harnessing the Power of Big Data to Improve Graduate Medical Education: Big Idea or Bust?

    Science.gov (United States)

    Arora, Vineet M

    2018-06-01

    With the advent of electronic medical records (EMRs) fueling the rise of big data, the use of predictive analytics, machine learning, and artificial intelligence are touted as transformational tools to improve clinical care. While major investments are being made in using big data to transform health care delivery, little effort has been directed toward exploiting big data to improve graduate medical education (GME). Because our current system relies on faculty observations of competence, it is not unreasonable to ask whether big data in the form of clinical EMRs and other novel data sources can answer questions of importance in GME such as when is a resident ready for independent practice.The timing is ripe for such a transformation. A recent National Academy of Medicine report called for reforms to how GME is delivered and financed. While many agree on the need to ensure that GME meets our nation's health needs, there is little consensus on how to measure the performance of GME in meeting this goal. During a recent workshop at the National Academy of Medicine on GME outcomes and metrics in October 2017, a key theme emerged: Big data holds great promise to inform GME performance at individual, institutional, and national levels. In this Invited Commentary, several examples are presented, such as using big data to inform clinical experience and provide clinically meaningful data to trainees, and using novel data sources, including ambient data, to better measure the quality of GME training.

  15. A SWOT Analysis of Big Data

    Science.gov (United States)

    Ahmadi, Mohammad; Dileepan, Parthasarati; Wheatley, Kathleen K.

    2016-01-01

    This is the decade of data analytics and big data, but not everyone agrees with the definition of big data. Some researchers see it as the future of data analysis, while others consider it as hype and foresee its demise in the near future. No matter how it is defined, big data for the time being is having its glory moment. The most important…

  16. A survey of big data research

    Science.gov (United States)

    Fang, Hua; Zhang, Zhaoyang; Wang, Chanpaul Jin; Daneshmand, Mahmoud; Wang, Chonggang; Wang, Honggang

    2015-01-01

    Big data create values for business and research, but pose significant challenges in terms of networking, storage, management, analytics and ethics. Multidisciplinary collaborations from engineers, computer scientists, statisticians and social scientists are needed to tackle, discover and understand big data. This survey presents an overview of big data initiatives, technologies and research in industries and academia, and discusses challenges and potential solutions. PMID:26504265

  17. Big Data in Action for Government : Big Data Innovation in Public Services, Policy, and Engagement

    OpenAIRE

    World Bank

    2017-01-01

    Governments have an opportunity to harness big data solutions to improve productivity, performance and innovation in service delivery and policymaking processes. In developing countries, governments have an opportunity to adopt big data solutions and leapfrog traditional administrative approaches

  18. Unraveling the Mystery of the Blue Fog: Structure, Properties, and Applications of Amorphous Blue Phase III.

    Science.gov (United States)

    Gandhi, Sahil Sandesh; Chien, Liang-Chy

    2017-12-01

    The amorphous blue phase III of cholesteric liquid crystals, also known as the "blue fog," are among the rising stars in materials science that can potentially be used to develop next-generation displays with the ability to compete toe-to-toe with disruptive technologies like organic light-emitting diodes. The structure and properties of the practically unobservable blue phase III have eluded scientists for more than a century since it was discovered. This progress report reviews the developments in this field from both fundamental and applied research perspectives. The first part of this progress report gives an overview of the 130-years-long scientific tour-de-force that very recently resulted in the revelation of the mysterious structure of blue phase III. The second part reviews progress made in the past decade in developing electrooptical, optical, and photonic devices based on blue phase III. The strong and weak aspects of the development of these devices are underlined and criticized, respectively. The third- and-final part proposes ideas for further improvement in blue phase III technology to make it feasible for commercialization and widespread use. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. 78 FR 3911 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive...

    Science.gov (United States)

    2013-01-17

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N259; FXRS1265030000-134-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive... significant impact (FONSI) for the environmental assessment (EA) for Big Stone National Wildlife Refuge...

  20. Big domains are novel Ca²+-binding modules: evidences from big domains of Leptospira immunoglobulin-like (Lig proteins.

    Directory of Open Access Journals (Sweden)

    Rajeev Raman

    Full Text Available BACKGROUND: Many bacterial surface exposed proteins mediate the host-pathogen interaction more effectively in the presence of Ca²+. Leptospiral immunoglobulin-like (Lig proteins, LigA and LigB, are surface exposed proteins containing Bacterial immunoglobulin like (Big domains. The function of proteins which contain Big fold is not known. Based on the possible similarities of immunoglobulin and βγ-crystallin folds, we here explore the important question whether Ca²+ binds to a Big domains, which would provide a novel functional role of the proteins containing Big fold. PRINCIPAL FINDINGS: We selected six individual Big domains for this study (three from the conserved part of LigA and LigB, denoted as Lig A3, Lig A4, and LigBCon5; two from the variable region of LigA, i.e., 9(th (Lig A9 and 10(th repeats (Lig A10; and one from the variable region of LigB, i.e., LigBCen2. We have also studied the conserved region covering the three and six repeats (LigBCon1-3 and LigCon. All these proteins bind the calcium-mimic dye Stains-all. All the selected four domains bind Ca²+ with dissociation constants of 2-4 µM. Lig A9 and Lig A10 domains fold well with moderate thermal stability, have β-sheet conformation and form homodimers. Fluorescence spectra of Big domains show a specific doublet (at 317 and 330 nm, probably due to Trp interaction with a Phe residue. Equilibrium unfolding of selected Big domains is similar and follows a two-state model, suggesting the similarity in their fold. CONCLUSIONS: We demonstrate that the Lig are Ca²+-binding proteins, with Big domains harbouring the binding motif. We conclude that despite differences in sequence, a Big motif binds Ca²+. This work thus sets up a strong possibility for classifying the proteins containing Big domains as a novel family of Ca²+-binding proteins. Since Big domain is a part of many proteins in bacterial kingdom, we suggest a possible function these proteins via Ca²+ binding.

  1. "Blue-Collar Blues" : kõigi maade töötud, ühinege! / Ants Juske

    Index Scriptorium Estoniae

    Juske, Ants, 1956-2016

    2009-01-01

    Rahvusvaheline näitus "Blue-Collar Blues" Tallinna Kunstihoones ja Kunstihoone galeriis 31. jaanuarini 2010. Kuraator Anders Härm. Näituse ajendiks on 1. juulist 2009 Eestis kehtima hakanud töölepinguseadus, näituse fookus on töösuhetel

  2. International joint research project of venture seeds excavating type in fiscal 1999 (revised) - venture seeds No.3. Report on achievements in developing bump forming technologies for high-density semiconductor connection; 1999 nendo (hosei) venture seeds hakkutsugata kokusai kyodo kenkyu jigyo - venture seeds No.3. Komitsudo handotai setsuzokuyo bump gata keisei gijutsu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Development has been advanced on a new flip chip technology with high efficiency and reliability to mount on lead frames and substrates the semiconductor devices that have been made higher in density and function and smaller in size. Specifically, discussions were given on a bump forming technology using micro balls with high accuracy and sphericity. With this technology, bumps are formed with high accuracy and efficiency by transferring and bonding the micro balls onto electrodes. Activities were taken in the following five areas: 1) discussions on the micro ball arranging technology, 2) optimization and evaluation on bed films, 3) manufacture and evaluation on micro balls, 4) overall evaluation and improvement discussion on quality and cost, and 5) analysis of thermal stress on soldered balls. In Item 1), micro balls are transferred onto pads after removing excess balls by sucking them into a suction head while having the micro balls float in a container by means of vibration. The suction arrangement plates were discussed and the suction system was optimized, whereas it was verified that balls with diameter of 100 {mu} m can be transferred and bonded onto pads of the chips without excess and insufficiency. (NEDO)

  3. New 'bigs' in cosmology

    International Nuclear Information System (INIS)

    Yurov, Artyom V.; Martin-Moruno, Prado; Gonzalez-Diaz, Pedro F.

    2006-01-01

    This paper contains a detailed discussion on new cosmic solutions describing the early and late evolution of a universe that is filled with a kind of dark energy that may or may not satisfy the energy conditions. The main distinctive property of the resulting space-times is that they make to appear twice the single singular events predicted by the corresponding quintessential (phantom) models in a manner which can be made symmetric with respect to the origin of cosmic time. Thus, big bang and big rip singularity are shown to take place twice, one on the positive branch of time and the other on the negative one. We have also considered dark energy and phantom energy accretion onto black holes and wormholes in the context of these new cosmic solutions. It is seen that the space-times of these holes would then undergo swelling processes leading to big trip and big hole events taking place on distinct epochs along the evolution of the universe. In this way, the possibility is considered that the past and future be connected in a non-paradoxical manner in the universes described by means of the new symmetric solutions

  4. 2nd INNS Conference on Big Data

    CERN Document Server

    Manolopoulos, Yannis; Iliadis, Lazaros; Roy, Asim; Vellasco, Marley

    2017-01-01

    The book offers a timely snapshot of neural network technologies as a significant component of big data analytics platforms. It promotes new advances and research directions in efficient and innovative algorithmic approaches to analyzing big data (e.g. deep networks, nature-inspired and brain-inspired algorithms); implementations on different computing platforms (e.g. neuromorphic, graphics processing units (GPUs), clouds, clusters); and big data analytics applications to solve real-world problems (e.g. weather prediction, transportation, energy management). The book, which reports on the second edition of the INNS Conference on Big Data, held on October 23–25, 2016, in Thessaloniki, Greece, depicts an interesting collaborative adventure of neural networks with big data and other learning technologies.

  5. Poporodní blues – česká adaptace dotazníku „Maternity blues questionnaire“

    Czech Academy of Sciences Publication Activity Database

    Takács, L.; Smolík, Filip; Mlíková Seidlerová, J.; Čepický, P.; Hoskovcová, S.

    2016-01-01

    Roč. 81, č. 5 (2016), s. 355-368 ISSN 1210-7832 Institutional support: RVO:68081740 Keywords : EPDS postpartum mood * Maternity Blues Questionnaire * postnatal depression * postpartum blues * postpartum depression Subject RIV: AN - Psychology

  6. The ethics of biomedical big data

    CERN Document Server

    Mittelstadt, Brent Daniel

    2016-01-01

    This book presents cutting edge research on the new ethical challenges posed by biomedical Big Data technologies and practices. ‘Biomedical Big Data’ refers to the analysis of aggregated, very large datasets to improve medical knowledge and clinical care. The book describes the ethical problems posed by aggregation of biomedical datasets and re-use/re-purposing of data, in areas such as privacy, consent, professionalism, power relationships, and ethical governance of Big Data platforms. Approaches and methods are discussed that can be used to address these problems to achieve the appropriate balance between the social goods of biomedical Big Data research and the safety and privacy of individuals. Seventeen original contributions analyse the ethical, social and related policy implications of the analysis and curation of biomedical Big Data, written by leading experts in the areas of biomedical research, medical and technology ethics, privacy, governance and data protection. The book advances our understan...

  7. Scalable privacy-preserving big data aggregation mechanism

    Directory of Open Access Journals (Sweden)

    Dapeng Wu

    2016-08-01

    Full Text Available As the massive sensor data generated by large-scale Wireless Sensor Networks (WSNs recently become an indispensable part of ‘Big Data’, the collection, storage, transmission and analysis of the big sensor data attract considerable attention from researchers. Targeting the privacy requirements of large-scale WSNs and focusing on the energy-efficient collection of big sensor data, a Scalable Privacy-preserving Big Data Aggregation (Sca-PBDA method is proposed in this paper. Firstly, according to the pre-established gradient topology structure, sensor nodes in the network are divided into clusters. Secondly, sensor data is modified by each node according to the privacy-preserving configuration message received from the sink. Subsequently, intra- and inter-cluster data aggregation is employed during the big sensor data reporting phase to reduce energy consumption. Lastly, aggregated results are recovered by the sink to complete the privacy-preserving big data aggregation. Simulation results validate the efficacy and scalability of Sca-PBDA and show that the big sensor data generated by large-scale WSNs is efficiently aggregated to reduce network resource consumption and the sensor data privacy is effectively protected to meet the ever-growing application requirements.

  8. Ethische aspecten van big data

    NARCIS (Netherlands)

    N. (Niek) van Antwerpen; Klaas Jan Mollema

    2017-01-01

    Big data heeft niet alleen geleid tot uitdagende technische vraagstukken, ook gaat het gepaard met allerlei nieuwe ethische en morele kwesties. Om verantwoord met big data om te gaan, moet ook over deze kwesties worden nagedacht. Want slecht datagebruik kan nadelige gevolgen hebben voor

  9. Epidemiology in wonderland: Big Data and precision medicine.

    Science.gov (United States)

    Saracci, Rodolfo

    2018-03-01

    Big Data and precision medicine, two major contemporary challenges for epidemiology, are critically examined from two different angles. In Part 1 Big Data collected for research purposes (Big research Data) and Big Data used for research although collected for other primary purposes (Big secondary Data) are discussed in the light of the fundamental common requirement of data validity, prevailing over "bigness". Precision medicine is treated developing the key point that high relative risks are as a rule required to make a variable or combination of variables suitable for prediction of disease occurrence, outcome or response to treatment; the commercial proliferation of allegedly predictive tests of unknown or poor validity is commented. Part 2 proposes a "wise epidemiology" approach to: (a) choosing in a context imprinted by Big Data and precision medicine-epidemiological research projects actually relevant to population health, (b) training epidemiologists, (c) investigating the impact on clinical practices and doctor-patient relation of the influx of Big Data and computerized medicine and (d) clarifying whether today "health" may be redefined-as some maintain in purely technological terms.

  10. Big Data and Analytics in Healthcare.

    Science.gov (United States)

    Tan, S S-L; Gao, G; Koch, S

    2015-01-01

    This editorial is part of the Focus Theme of Methods of Information in Medicine on "Big Data and Analytics in Healthcare". The amount of data being generated in the healthcare industry is growing at a rapid rate. This has generated immense interest in leveraging the availability of healthcare data (and "big data") to improve health outcomes and reduce costs. However, the nature of healthcare data, and especially big data, presents unique challenges in processing and analyzing big data in healthcare. This Focus Theme aims to disseminate some novel approaches to address these challenges. More specifically, approaches ranging from efficient methods of processing large clinical data to predictive models that could generate better predictions from healthcare data are presented.

  11. Big Data for Business Ecosystem Players

    Directory of Open Access Journals (Sweden)

    Perko Igor

    2016-06-01

    Full Text Available In the provided research, some of the Big Data most prospective usage domains connect with distinguished player groups found in the business ecosystem. Literature analysis is used to identify the state of the art of Big Data related research in the major domains of its use-namely, individual marketing, health treatment, work opportunities, financial services, and security enforcement. System theory was used to identify business ecosystem major player types disrupted by Big Data: individuals, small and mid-sized enterprises, large organizations, information providers, and regulators. Relationships between the domains and players were explained through new Big Data opportunities and threats and by players’ responsive strategies. System dynamics was used to visualize relationships in the provided model.

  12. "Big data" in economic history.

    Science.gov (United States)

    Gutmann, Myron P; Merchant, Emily Klancher; Roberts, Evan

    2018-03-01

    Big data is an exciting prospect for the field of economic history, which has long depended on the acquisition, keying, and cleaning of scarce numerical information about the past. This article examines two areas in which economic historians are already using big data - population and environment - discussing ways in which increased frequency of observation, denser samples, and smaller geographic units allow us to analyze the past with greater precision and often to track individuals, places, and phenomena across time. We also explore promising new sources of big data: organically created economic data, high resolution images, and textual corpora.

  13. Big Data Knowledge in Global Health Education.

    Science.gov (United States)

    Olayinka, Olaniyi; Kekeh, Michele; Sheth-Chandra, Manasi; Akpinar-Elci, Muge

    The ability to synthesize and analyze massive amounts of data is critical to the success of organizations, including those that involve global health. As countries become highly interconnected, increasing the risk for pandemics and outbreaks, the demand for big data is likely to increase. This requires a global health workforce that is trained in the effective use of big data. To assess implementation of big data training in global health, we conducted a pilot survey of members of the Consortium of Universities of Global Health. More than half the respondents did not have a big data training program at their institution. Additionally, the majority agreed that big data training programs will improve global health deliverables, among other favorable outcomes. Given the observed gap and benefits, global health educators may consider investing in big data training for students seeking a career in global health. Copyright © 2017 Icahn School of Medicine at Mount Sinai. Published by Elsevier Inc. All rights reserved.

  14. GEOSS: Addressing Big Data Challenges

    Science.gov (United States)

    Nativi, S.; Craglia, M.; Ochiai, O.

    2014-12-01

    In the sector of Earth Observation, the explosion of data is due to many factors including: new satellite constellations, the increased capabilities of sensor technologies, social media, crowdsourcing, and the need for multidisciplinary and collaborative research to face Global Changes. In this area, there are many expectations and concerns about Big Data. Vendors have attempted to use this term for their commercial purposes. It is necessary to understand whether Big Data is a radical shift or an incremental change for the existing digital infrastructures. This presentation tries to explore and discuss the impact of Big Data challenges and new capabilities on the Global Earth Observation System of Systems (GEOSS) and particularly on its common digital infrastructure called GCI. GEOSS is a global and flexible network of content providers allowing decision makers to access an extraordinary range of data and information at their desk. The impact of the Big Data dimensionalities (commonly known as 'V' axes: volume, variety, velocity, veracity, visualization) on GEOSS is discussed. The main solutions and experimentation developed by GEOSS along these axes are introduced and analyzed. GEOSS is a pioneering framework for global and multidisciplinary data sharing in the Earth Observation realm; its experience on Big Data is valuable for the many lessons learned.

  15. Big data for bipolar disorder.

    Science.gov (United States)

    Monteith, Scott; Glenn, Tasha; Geddes, John; Whybrow, Peter C; Bauer, Michael

    2016-12-01

    The delivery of psychiatric care is changing with a new emphasis on integrated care, preventative measures, population health, and the biological basis of disease. Fundamental to this transformation are big data and advances in the ability to analyze these data. The impact of big data on the routine treatment of bipolar disorder today and in the near future is discussed, with examples that relate to health policy, the discovery of new associations, and the study of rare events. The primary sources of big data today are electronic medical records (EMR), claims, and registry data from providers and payers. In the near future, data created by patients from active monitoring, passive monitoring of Internet and smartphone activities, and from sensors may be integrated with the EMR. Diverse data sources from outside of medicine, such as government financial data, will be linked for research. Over the long term, genetic and imaging data will be integrated with the EMR, and there will be more emphasis on predictive models. Many technical challenges remain when analyzing big data that relates to size, heterogeneity, complexity, and unstructured text data in the EMR. Human judgement and subject matter expertise are critical parts of big data analysis, and the active participation of psychiatrists is needed throughout the analytical process.

  16. BIG DATA IN TAMIL: OPPORTUNITIES, BENEFITS AND CHALLENGES

    OpenAIRE

    R.S. Vignesh Raj; Babak Khazaei; Ashik Ali

    2015-01-01

    This paper gives an overall introduction on big data and has tried to introduce Big Data in Tamil. It discusses the potential opportunities, benefits and likely challenges from a very Tamil and Tamil Nadu perspective. The paper has also made original contribution by proposing the ‘big data’s’ terminology in Tamil. The paper further suggests a few areas to explore using big data Tamil on the lines of the Tamil Nadu Government ‘vision 2023’. Whilst, big data has something to offer everyone, it ...

  17. Effect of surfactant on electrodeposited Ni-P layer as an under bump metallization

    International Nuclear Information System (INIS)

    Lin, Yung-Chi; Duh, Jenq-Gong

    2007-01-01

    In the microelectronic industry, the nickel plating has been used as the under bump metallization (UBM). The electroplated process was demonstrated to be a favorable alternative approach to produce the Ni-P layer as UBM. In this study, the role of sodium dodecylsulfate (SDS) addition in electrodeposition was investigated. The variations on surface morphology and surface roughness in the SDS-added process of electroplated Ni-P were revealed with both field emission scanning electronic microscope and atomic force microscope. The influence of SDS addition process in wettability of several commercial solder pastes, including Sn-37Pb, Sn-3.5Ag, and Sn-3.0Ag-0.5Cu, on electroplated Ni-P with various phosphorous contents was evaluated. The surface morphology and the surface roughness of Ni-P layer were affected by SDS addition. It was demonstrated that modified surface morphology and surface roughness acted to enhance the wettability of electroplated Ni-P. In addition, the interfacial reactions between Sn-3.0Ag-0.5Cu and electroplated Ni-P UBM with SDS addition during deposition was also probed and discussed

  18. Big data in biomedicine.

    Science.gov (United States)

    Costa, Fabricio F

    2014-04-01

    The increasing availability and growth rate of biomedical information, also known as 'big data', provides an opportunity for future personalized medicine programs that will significantly improve patient care. Recent advances in information technology (IT) applied to biomedicine are changing the landscape of privacy and personal information, with patients getting more control of their health information. Conceivably, big data analytics is already impacting health decisions and patient care; however, specific challenges need to be addressed to integrate current discoveries into medical practice. In this article, I will discuss the major breakthroughs achieved in combining omics and clinical health data in terms of their application to personalized medicine. I will also review the challenges associated with using big data in biomedicine and translational science. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. 76 FR 22923 - Wellpoint, Inc. D/B/A/Anthem Blue Cross & Blue Shield Enterprise Provider Data Management Team...

    Science.gov (United States)

    2011-04-25

    .../B/A/Anthem Blue Cross & Blue Shield Enterprise Provider Data Management Team Including On-Site... & Blue Shield, Enterprise Provider Data Management Team, Including On-Site Leased Workers From Kelly... Of Kentucky, Enterprise Provider Data Management Team, Louisville, Kentucky TA-W-74,895B Wellpoint...

  20. Big Data’s Role in Precision Public Health

    Science.gov (United States)

    Dolley, Shawn

    2018-01-01

    Precision public health is an emerging practice to more granularly predict and understand public health risks and customize treatments for more specific and homogeneous subpopulations, often using new data, technologies, and methods. Big data is one element that has consistently helped to achieve these goals, through its ability to deliver to practitioners a volume and variety of structured or unstructured data not previously possible. Big data has enabled more widespread and specific research and trials of stratifying and segmenting populations at risk for a variety of health problems. Examples of success using big data are surveyed in surveillance and signal detection, predicting future risk, targeted interventions, and understanding disease. Using novel big data or big data approaches has risks that remain to be resolved. The continued growth in volume and variety of available data, decreased costs of data capture, and emerging computational methods mean big data success will likely be a required pillar of precision public health into the future. This review article aims to identify the precision public health use cases where big data has added value, identify classes of value that big data may bring, and outline the risks inherent in using big data in precision public health efforts. PMID:29594091

  1. Big inquiry

    Energy Technology Data Exchange (ETDEWEB)

    Wynne, B [Lancaster Univ. (UK)

    1979-06-28

    The recently published report entitled 'The Big Public Inquiry' from the Council for Science and Society and the Outer Circle Policy Unit is considered, with especial reference to any future enquiry which may take place into the first commercial fast breeder reactor. Proposals embodied in the report include stronger rights for objectors and an attempt is made to tackle the problem that participation in a public inquiry is far too late to be objective. It is felt by the author that the CSS/OCPU report is a constructive contribution to the debate about big technology inquiries but that it fails to understand the deeper currents in the economic and political structure of technology which so influence the consequences of whatever formal procedures are evolved.

  2. Fast Blue RR—Siloxane Derivatized Materials Indicate Wound Infection Due to a Deep Blue Color Development

    Directory of Open Access Journals (Sweden)

    Doris Schiffer

    2015-09-01

    Full Text Available There is a strong need for simple and fast methods for wound infection determination. Myeloperoxidase, an immune system-derived enzyme was found to be a suitable biomarker for wound infection. Hence, alkoxysilane-derivatized Fast Blue RR was immobilized via simple hydrolytic polymerization. The resulting enzyme-responsive siloxane layers were incubated with myeloperoxidase, wound fluid or hemoglobin. The reaction was monitored via HPLC measurements and the color development quantified spectrophotometrically. Myeloperoxidase was indeed able to oxidize immobilized Fast Blue RR leading to a blue colored product. No conversion was detected in non-infected wound fluids. The visible color changes of these novel materials towards blue enable an easy distinction between infected and non-infected wound fluids.

  3. Big data analytics with R and Hadoop

    CERN Document Server

    Prajapati, Vignesh

    2013-01-01

    Big Data Analytics with R and Hadoop is a tutorial style book that focuses on all the powerful big data tasks that can be achieved by integrating R and Hadoop.This book is ideal for R developers who are looking for a way to perform big data analytics with Hadoop. This book is also aimed at those who know Hadoop and want to build some intelligent applications over Big data with R packages. It would be helpful if readers have basic knowledge of R.

  4. Big data in forensic science and medicine.

    Science.gov (United States)

    Lefèvre, Thomas

    2018-07-01

    In less than a decade, big data in medicine has become quite a phenomenon and many biomedical disciplines got their own tribune on the topic. Perspectives and debates are flourishing while there is a lack for a consensual definition for big data. The 3Vs paradigm is frequently evoked to define the big data principles and stands for Volume, Variety and Velocity. Even according to this paradigm, genuine big data studies are still scarce in medicine and may not meet all expectations. On one hand, techniques usually presented as specific to the big data such as machine learning techniques are supposed to support the ambition of personalized, predictive and preventive medicines. These techniques are mostly far from been new and are more than 50 years old for the most ancient. On the other hand, several issues closely related to the properties of big data and inherited from other scientific fields such as artificial intelligence are often underestimated if not ignored. Besides, a few papers temper the almost unanimous big data enthusiasm and are worth attention since they delineate what is at stakes. In this context, forensic science is still awaiting for its position papers as well as for a comprehensive outline of what kind of contribution big data could bring to the field. The present situation calls for definitions and actions to rationally guide research and practice in big data. It is an opportunity for grounding a true interdisciplinary approach in forensic science and medicine that is mainly based on evidence. Copyright © 2017 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  5. Heart tissue of harlequin (hq)/Big Blue mice has elevated reactive oxygen species without significant impact on the frequency and nature of point mutations in nuclear DNA

    Energy Technology Data Exchange (ETDEWEB)

    Crabbe, Rory A. [Department of Biology, University of Western Ontario, London, Ontario, N6A 5B7 (Canada); Hill, Kathleen A., E-mail: khill22@uwo.ca [Department of Biology, University of Western Ontario, London, Ontario, N6A 5B7 (Canada)

    2010-09-10

    Age is a major risk factor for heart disease, and cardiac aging is characterized by elevated mitochondrial reactive oxygen species (ROS) with compromised mitochondrial and nuclear DNA integrity. To assess links between increased ROS levels and mutations, we examined in situ levels of ROS and cII mutation frequency, pattern and spectrum in the heart of harlequin (hq)/Big Blue mice. The hq mouse is a model of premature aging with mitochondrial dysfunction and increased risk of oxidative stress-induced heart disease with the means for in vivo mutation detection. The hq mutation produces a significant downregulation in the X-linked apoptosis-inducing factor gene (Aif) impairing both the antioxidant and oxidative phosphorylation functions of AIF. Brain and skin of hq disease mice have elevated frequencies of point mutations in nuclear DNA and histopathology characterized by cell loss. Reports of associated elevations in ROS in brain and skin have mixed results. Herein, heart in situ ROS levels were elevated in hq disease compared to AIF-proficient mice (p < 0.0001) yet, mutation frequency and pattern were similar in hq disease, hq carrier and AIF-proficient mice. Heart cII mutations were also assessed 15 days following an acute exposure to an exogenous ROS inducer (10 mg paraquat/kg). Acute paraquat exposure with a short mutant manifestation period was insufficient to elevate mutation frequency or alter mutation pattern in the post-mitotic heart tissue of AIF-proficient mice. Paraquat induction of ROS requires mitochondrial complex I and thus is likely compromised in hq mice. Results of this preliminary survey and the context of recent literature suggest that determining causal links between AIF deficiency and the premature aging phenotypes of specific tissues is better addressed with assay of mitochondrial ROS and large-scale changes in mitochondrial DNA in specific cell types.

  6. Heart tissue of harlequin (hq)/Big Blue mice has elevated reactive oxygen species without significant impact on the frequency and nature of point mutations in nuclear DNA

    International Nuclear Information System (INIS)

    Crabbe, Rory A.; Hill, Kathleen A.

    2010-01-01

    Age is a major risk factor for heart disease, and cardiac aging is characterized by elevated mitochondrial reactive oxygen species (ROS) with compromised mitochondrial and nuclear DNA integrity. To assess links between increased ROS levels and mutations, we examined in situ levels of ROS and cII mutation frequency, pattern and spectrum in the heart of harlequin (hq)/Big Blue mice. The hq mouse is a model of premature aging with mitochondrial dysfunction and increased risk of oxidative stress-induced heart disease with the means for in vivo mutation detection. The hq mutation produces a significant downregulation in the X-linked apoptosis-inducing factor gene (Aif) impairing both the antioxidant and oxidative phosphorylation functions of AIF. Brain and skin of hq disease mice have elevated frequencies of point mutations in nuclear DNA and histopathology characterized by cell loss. Reports of associated elevations in ROS in brain and skin have mixed results. Herein, heart in situ ROS levels were elevated in hq disease compared to AIF-proficient mice (p < 0.0001) yet, mutation frequency and pattern were similar in hq disease, hq carrier and AIF-proficient mice. Heart cII mutations were also assessed 15 days following an acute exposure to an exogenous ROS inducer (10 mg paraquat/kg). Acute paraquat exposure with a short mutant manifestation period was insufficient to elevate mutation frequency or alter mutation pattern in the post-mitotic heart tissue of AIF-proficient mice. Paraquat induction of ROS requires mitochondrial complex I and thus is likely compromised in hq mice. Results of this preliminary survey and the context of recent literature suggest that determining causal links between AIF deficiency and the premature aging phenotypes of specific tissues is better addressed with assay of mitochondrial ROS and large-scale changes in mitochondrial DNA in specific cell types.

  7. Genomic copy number analysis of a spectrum of blue nevi identifies recurrent aberrations of entire chromosomal arms in melanoma ex blue nevus.

    Science.gov (United States)

    Chan, May P; Andea, Aleodor A; Harms, Paul W; Durham, Alison B; Patel, Rajiv M; Wang, Min; Robichaud, Patrick; Fisher, Gary J; Johnson, Timothy M; Fullen, Douglas R

    2016-03-01

    Blue nevi may display significant atypia or undergo malignant transformation. Morphologic diagnosis of this spectrum of lesions is notoriously difficult, and molecular tools are increasingly used to improve diagnostic accuracy. We studied copy number aberrations in a cohort of cellular blue nevi, atypical cellular blue nevi, and melanomas ex blue nevi using Affymetrix's OncoScan platform. Cases with sufficient DNA were analyzed for GNAQ, GNA11, and HRAS mutations. Copy number aberrations were detected in 0 of 5 (0%) cellular blue nevi, 3 of 12 (25%) atypical cellular blue nevi, and 6 of 9 (67%) melanomas ex blue nevi. None of the atypical cellular blue nevi displayed more than one aberration, whereas complex aberrations involving four or more regions were seen exclusively in melanomas ex blue nevi. Gains and losses of entire chromosomal arms were identified in four of five melanomas ex blue nevi with copy number aberrations. In particular, gains of 1q, 4p, 6p, and 8q, and losses of 1p and 4q were each found in at least two melanomas. Whole chromosome aberrations were also common, and represented the sole finding in one atypical cellular blue nevus. When seen in melanomas, however, whole chromosome aberrations were invariably accompanied by partial aberrations of other chromosomes. Three melanomas ex blue nevi harbored aberrations, which were absent or negligible in their precursor components, suggesting progression in tumor biology. Gene mutations involving GNAQ and GNA11 were each detected in two of eight melanomas ex blue nevi. In conclusion, copy number aberrations are more common and often complex in melanomas ex blue nevi compared with cellular and atypical cellular blue nevi. Identification of recurrent gains and losses of entire chromosomal arms in melanomas ex blue nevi suggests that development of new probes targeting these regions may improve detection and risk stratification of these lesions.

  8. NASA's Big Data Task Force

    Science.gov (United States)

    Holmes, C. P.; Kinter, J. L.; Beebe, R. F.; Feigelson, E.; Hurlburt, N. E.; Mentzel, C.; Smith, G.; Tino, C.; Walker, R. J.

    2017-12-01

    Two years ago NASA established the Ad Hoc Big Data Task Force (BDTF - https://science.nasa.gov/science-committee/subcommittees/big-data-task-force), an advisory working group with the NASA Advisory Council system. The scope of the Task Force included all NASA Big Data programs, projects, missions, and activities. The Task Force focused on such topics as exploring the existing and planned evolution of NASA's science data cyber-infrastructure that supports broad access to data repositories for NASA Science Mission Directorate missions; best practices within NASA, other Federal agencies, private industry and research institutions; and Federal initiatives related to big data and data access. The BDTF has completed its two-year term and produced several recommendations plus four white papers for NASA's Science Mission Directorate. This presentation will discuss the activities and results of the TF including summaries of key points from its focused study topics. The paper serves as an introduction to the papers following in this ESSI session.

  9. Big Data Technologies

    Science.gov (United States)

    Bellazzi, Riccardo; Dagliati, Arianna; Sacchi, Lucia; Segagni, Daniele

    2015-01-01

    The so-called big data revolution provides substantial opportunities to diabetes management. At least 3 important directions are currently of great interest. First, the integration of different sources of information, from primary and secondary care to administrative information, may allow depicting a novel view of patient’s care processes and of single patient’s behaviors, taking into account the multifaceted nature of chronic care. Second, the availability of novel diabetes technologies, able to gather large amounts of real-time data, requires the implementation of distributed platforms for data analysis and decision support. Finally, the inclusion of geographical and environmental information into such complex IT systems may further increase the capability of interpreting the data gathered and extract new knowledge from them. This article reviews the main concepts and definitions related to big data, it presents some efforts in health care, and discusses the potential role of big data in diabetes care. Finally, as an example, it describes the research efforts carried on in the MOSAIC project, funded by the European Commission. PMID:25910540

  10. The Berlin Inventory of Gambling behavior - Screening (BIG-S): Validation using a clinical sample.

    Science.gov (United States)

    Wejbera, Martin; Müller, Kai W; Becker, Jan; Beutel, Manfred E

    2017-05-18

    Published diagnostic questionnaires for gambling disorder in German are either based on DSM-III criteria or focus on aspects other than life time prevalence. This study was designed to assess the usability of the DSM-IV criteria based Berlin Inventory of Gambling Behavior Screening tool in a clinical sample and adapt it to DSM-5 criteria. In a sample of 432 patients presenting for behavioral addiction assessment at the University Medical Center Mainz, we checked the screening tool's results against clinical diagnosis and compared a subsample of n=300 clinically diagnosed gambling disorder patients with a comparison group of n=132. The BIG-S produced a sensitivity of 99.7% and a specificity of 96.2%. The instrument's unidimensionality and the diagnostic improvements of DSM-5 criteria were verified by exploratory and confirmatory factor analysis as well as receiver operating characteristic analysis. The BIG-S is a reliable and valid screening tool for gambling disorder and demonstrated its concise and comprehensible operationalization of current DSM-5 criteria in a clinical setting.

  11. The lithium abundance of M67 blue stragglers - A constraint on the blue straggler phenomenon

    International Nuclear Information System (INIS)

    Pritchet, C.J.; Glaspey, J.W.

    1991-01-01

    Upper limits have been placed on the line strength of the 6707 A Li I resonance doublet in seven blue stragglers in M67. The corresponding upper limits on abundances range from log N(Li) less than about 1.3 to less than about 2.3. This result is significantly below the level of log N(Li) about 3.1 + or - 0.1 found in field main-sequence stars of comparable temperature. It is concluded that some form of mixing has affected the outer envelopes of blue stragglers. (Such mixing has been proposed as the mechanism needed to prolong the lifetimes of blue stragglers relative to normal main-sequence stars at the same luminosity). Virtually all mechanisms for the production of blue stragglers other than mixing, binary mass transfer, or binary coalescence appear to be ruled out by the present observations. 45 refs

  12. Franz Joseph Gall and music: the faculty and the bump.

    Science.gov (United States)

    Eling, Paul; Finger, Stanley; Whitaker, Harry

    2015-01-01

    The traditional story maintains that Franz Joseph Gall's (1758-1828) scientific program began with his observations of schoolmates with bulging eyes and good verbal memories. But his search to understand human nature, in particular individual differences in capacities, passions, and tendencies, can also be traced to other important observations, one being of a young girl with an exceptional talent for music. Rejecting contemporary notions of cognition, Gall concluded that behavior results from the interaction of a limited set of basic faculties, each with its own processes for perception and memory, each with its own territory in both cerebral or cerebellar cortices. Gall identified 27 faculties, one being the sense of tone relations or music. The description of the latter is identical in both his Anatomie et Physiologie and Sur les Fonctions du Cerveau et sur Celles de Chacune de ses Parties, where he provided positive and negative evidences and discussed findings from humans and lower animals, for the faculty. The localization of the cortical faculty for talented musicians, he explained, is demonstrated by a "bump" on each side of the skull just above the angle of the eye; hence, the lower forehead of musicians is broader or squarer than in other individuals. Additionally, differences between singing and nonsinging birds also correlate with cranial features. Gall even brought age, racial, and national differences into the picture. What he wrote about music reveals much about his science and creative thinking. © 2015 Elsevier B.V. All rights reserved.

  13. Traffic information computing platform for big data

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Zongtao, E-mail: ztduan@chd.edu.cn; Li, Ying, E-mail: ztduan@chd.edu.cn; Zheng, Xibin, E-mail: ztduan@chd.edu.cn; Liu, Yan, E-mail: ztduan@chd.edu.cn; Dai, Jiting, E-mail: ztduan@chd.edu.cn; Kang, Jun, E-mail: ztduan@chd.edu.cn [Chang' an University School of Information Engineering, Xi' an, China and Shaanxi Engineering and Technical Research Center for Road and Traffic Detection, Xi' an (China)

    2014-10-06

    Big data environment create data conditions for improving the quality of traffic information service. The target of this article is to construct a traffic information computing platform for big data environment. Through in-depth analysis the connotation and technology characteristics of big data and traffic information service, a distributed traffic atomic information computing platform architecture is proposed. Under the big data environment, this type of traffic atomic information computing architecture helps to guarantee the traffic safety and efficient operation, more intelligent and personalized traffic information service can be used for the traffic information users.

  14. Traffic information computing platform for big data

    International Nuclear Information System (INIS)

    Duan, Zongtao; Li, Ying; Zheng, Xibin; Liu, Yan; Dai, Jiting; Kang, Jun

    2014-01-01

    Big data environment create data conditions for improving the quality of traffic information service. The target of this article is to construct a traffic information computing platform for big data environment. Through in-depth analysis the connotation and technology characteristics of big data and traffic information service, a distributed traffic atomic information computing platform architecture is proposed. Under the big data environment, this type of traffic atomic information computing architecture helps to guarantee the traffic safety and efficient operation, more intelligent and personalized traffic information service can be used for the traffic information users

  15. Fremtidens landbrug bliver big business

    DEFF Research Database (Denmark)

    Hansen, Henning Otte

    2016-01-01

    Landbrugets omverdensforhold og konkurrencevilkår ændres, og det vil nødvendiggøre en udvikling i retning af “big business“, hvor landbrugene bliver endnu større, mere industrialiserede og koncentrerede. Big business bliver en dominerende udvikling i dansk landbrug - men ikke den eneste...

  16. Quantum nature of the big bang.

    Science.gov (United States)

    Ashtekar, Abhay; Pawlowski, Tomasz; Singh, Parampreet

    2006-04-14

    Some long-standing issues concerning the quantum nature of the big bang are resolved in the context of homogeneous isotropic models with a scalar field. Specifically, the known results on the resolution of the big-bang singularity in loop quantum cosmology are significantly extended as follows: (i) the scalar field is shown to serve as an internal clock, thereby providing a detailed realization of the "emergent time" idea; (ii) the physical Hilbert space, Dirac observables, and semiclassical states are constructed rigorously; (iii) the Hamiltonian constraint is solved numerically to show that the big bang is replaced by a big bounce. Thanks to the nonperturbative, background independent methods, unlike in other approaches the quantum evolution is deterministic across the deep Planck regime.

  17. Mentoring in Schools: An Impact Study of Big Brothers Big Sisters School-Based Mentoring

    Science.gov (United States)

    Herrera, Carla; Grossman, Jean Baldwin; Kauh, Tina J.; McMaken, Jennifer

    2011-01-01

    This random assignment impact study of Big Brothers Big Sisters School-Based Mentoring involved 1,139 9- to 16-year-old students in 10 cities nationwide. Youth were randomly assigned to either a treatment group (receiving mentoring) or a control group (receiving no mentoring) and were followed for 1.5 school years. At the end of the first school…

  18. Big data processing in the cloud - Challenges and platforms

    Science.gov (United States)

    Zhelev, Svetoslav; Rozeva, Anna

    2017-12-01

    Choosing the appropriate architecture and technologies for a big data project is a difficult task, which requires extensive knowledge in both the problem domain and in the big data landscape. The paper analyzes the main big data architectures and the most widely implemented technologies used for processing and persisting big data. Clouds provide for dynamic resource scaling, which makes them a natural fit for big data applications. Basic cloud computing service models are presented. Two architectures for processing big data are discussed, Lambda and Kappa architectures. Technologies for big data persistence are presented and analyzed. Stream processing as the most important and difficult to manage is outlined. The paper highlights main advantages of cloud and potential problems.

  19. Ecology of blue straggler stars

    CERN Document Server

    Carraro, Giovanni; Beccari, Giacomo

    2015-01-01

    The existence of blue straggler stars, which appear younger, hotter, and more massive than their siblings, is at odds with a simple picture of stellar evolution. Such stars should have exhausted their nuclear fuel and evolved long ago to become cooling white dwarfs. They are found to exist in globular clusters, open clusters, dwarf spheroidal galaxies of the Local Group, OB associations and as field stars. This book summarises the many advances in observational and theoretical work dedicated to blue straggler stars. Carefully edited extended contributions by well-known experts in the field cover all the relevant aspects of blue straggler stars research: Observations of blue straggler stars in their various environments; Binary stars and formation channels; Dynamics of globular clusters; Interpretation of observational data and comparison with models. The book also offers an introductory chapter on stellar evolution written by the editors of the book.

  20. Ethics and Epistemology in Big Data Research.

    Science.gov (United States)

    Lipworth, Wendy; Mason, Paul H; Kerridge, Ian; Ioannidis, John P A

    2017-12-01

    Biomedical innovation and translation are increasingly emphasizing research using "big data." The hope is that big data methods will both speed up research and make its results more applicable to "real-world" patients and health services. While big data research has been embraced by scientists, politicians, industry, and the public, numerous ethical, organizational, and technical/methodological concerns have also been raised. With respect to technical and methodological concerns, there is a view that these will be resolved through sophisticated information technologies, predictive algorithms, and data analysis techniques. While such advances will likely go some way towards resolving technical and methodological issues, we believe that the epistemological issues raised by big data research have important ethical implications and raise questions about the very possibility of big data research achieving its goals.

  1. Victoria Stodden: Scholarly Communication in the Era of Big Data and Big Computation

    OpenAIRE

    Stodden, Victoria

    2015-01-01

    Victoria Stodden gave the keynote address for Open Access Week 2015. "Scholarly communication in the era of big data and big computation" was sponsored by the University Libraries, Computational Modeling and Data Analytics, the Department of Computer Science, the Department of Statistics, the Laboratory for Interdisciplinary Statistical Analysis (LISA), and the Virginia Bioinformatics Institute. Victoria Stodden is an associate professor in the Graduate School of Library and Information Scien...

  2. Big Data: Concept, Potentialities and Vulnerabilities

    Directory of Open Access Journals (Sweden)

    Fernando Almeida

    2018-03-01

    Full Text Available The evolution of information systems and the growth in the use of the Internet and social networks has caused an explosion in the amount of available data relevant to the activities of the companies. Therefore, the treatment of these available data is vital to support operational, tactical and strategic decisions. This paper aims to present the concept of big data and the main technologies that support the analysis of large data volumes. The potential of big data is explored considering nine sectors of activity, such as financial, retail, healthcare, transports, agriculture, energy, manufacturing, public, and media and entertainment. In addition, the main current opportunities, vulnerabilities and privacy challenges of big data are discussed. It was possible to conclude that despite the potential for using the big data to grow in the previously identified areas, there are still some challenges that need to be considered and mitigated, namely the privacy of information, the existence of qualified human resources to work with Big Data and the promotion of a data-driven organizational culture.

  3. Big data analytics a management perspective

    CERN Document Server

    Corea, Francesco

    2016-01-01

    This book is about innovation, big data, and data science seen from a business perspective. Big data is a buzzword nowadays, and there is a growing necessity within practitioners to understand better the phenomenon, starting from a clear stated definition. This book aims to be a starting reading for executives who want (and need) to keep the pace with the technological breakthrough introduced by new analytical techniques and piles of data. Common myths about big data will be explained, and a series of different strategic approaches will be provided. By browsing the book, it will be possible to learn how to implement a big data strategy and how to use a maturity framework to monitor the progress of the data science team, as well as how to move forward from one stage to the next. Crucial challenges related to big data will be discussed, where some of them are more general - such as ethics, privacy, and ownership – while others concern more specific business situations (e.g., initial public offering, growth st...

  4. Human factors in Big Data

    NARCIS (Netherlands)

    Boer, J. de

    2016-01-01

    Since 2014 I am involved in various (research) projects that try to make the hype around Big Data more concrete and tangible for the industry and government. Big Data is about multiple sources of (real-time) data that can be analysed, transformed to information and be used to make 'smart' decisions.

  5. Big Data Science Cafés: High School Students Experiencing Real Research with Scientists

    Science.gov (United States)

    Walker, C. E.; Pompea, S. M.

    2017-12-01

    The Education and Public Outreach group at the National Optical Astronomy Observatory has designed an outside-of-school education program to excite the interest of talented youth in future projects like the Large Synoptic Survey Telescope (LSST) and the NOAO (archival) Data Lab - their data approaches and key science projects. Originally funded by the LSST Corporation, the program cultivates talented youth to enter STEM disciplines and serves as a model to disseminate to the 40+ institutions involved in LSST. One Saturday a month during the academic year, high school students have the opportunity to interact with expert astronomers who work with large astronomical data sets in their scientific work. Students learn about killer asteroids, the birth and death of stars, colliding galaxies, the structure of the universe, gravitational waves, dark energy, dark matter, and more. The format for the Saturday science cafés has been a short presentation, discussion (plus food), computer lab activity and more discussion. They last about 2.5 hours and have been planned by a group of interested local high school students, an undergraduate student coordinator, the presenting astronomers, the program director and an evaluator. High school youth leaders help ensure an enjoyable and successful program for fellow students. They help their fellow students with the activities and help evaluate how well the science café went. Their remarks shape the next science café and improve the program. The experience offers youth leaders ownership of the program, opportunities to take on responsibilities and learn leadership and communication skills, as well as foster their continued interests in STEM. The prototype Big Data Science Academy was implemented successfully in the Spring 2017 and engaged almost 40 teens from greater Tucson in the fundamentals of astronomy concepts and research. As with any first implementation there were bumps. However, staff, scientists, and student leaders all

  6. Slaves to Big Data. Or Are We?

    Directory of Open Access Journals (Sweden)

    Mireille Hildebrandt

    2013-10-01

    Full Text Available

    In this contribution, the notion of Big Data is discussed in relation to the monetisation of personal data. The claim of some proponents, as well as adversaries, that Big Data implies that ‘n = all’, meaning that we no longer need to rely on samples because we have all the data, is scrutinised and found to be both overly optimistic and unnecessarily pessimistic. A set of epistemological and ethical issues is presented, focusing on the implications of Big Data for our perception, cognition, fairness, privacy and due process. The article then looks into the idea of user-centric personal data management to investigate to what extent it provides solutions for some of the problems triggered by the Big Data conundrum. Special attention is paid to the core principle of data protection legislation, namely purpose binding. Finally, this contribution seeks to inquire into the influence of Big Data politics on self, mind and society, and asks how we can prevent ourselves from becoming slaves to Big Data.

  7. Natural Blue Food Colour

    DEFF Research Database (Denmark)

    Roda-Serrat, Maria Cinta

    In recent years, there has been a growing tendency to avoid the use of artificial colorants and additives in food products, especially after some studies linked their consumption with behavioural changes in children. However, the incorporation of colorants from natural origin remains a challenge...... for food technologists, as these are typically less vivid and less stable than their synthetic alternatives. Regarding blue colorants, phycocyanins from cyanobacteria are currently in the spotlight as promising new natural blue colorants. Phycocyanins are proteins which blue colour results from...... the presence of the chromophore phycocyanobilin (PCB), a covalently attached linear tetrapyrrole. The applications of phycocyanins as food colorants are however limited, as they show poor stability in certain conditions of pH, light and temperature. Cleavage of PCB from the protein followed by careful product...

  8. Will Organization Design Be Affected By Big Data?

    Directory of Open Access Journals (Sweden)

    Giles Slinger

    2014-12-01

    Full Text Available Computing power and analytical methods allow us to create, collate, and analyze more data than ever before. When datasets are unusually large in volume, velocity, and variety, they are referred to as “big data.” Some observers have suggested that in order to cope with big data (a organizational structures will need to change and (b the processes used to design organizations will be different. In this article, we differentiate big data from relatively slow-moving, linked people data. We argue that big data will change organizational structures as organizations pursue the opportunities presented by big data. The processes by which organizations are designed, however, will be relatively unaffected by big data. Instead, organization design processes will be more affected by the complex links found in people data.

  9. Official statistics and Big Data

    Directory of Open Access Journals (Sweden)

    Peter Struijs

    2014-07-01

    Full Text Available The rise of Big Data changes the context in which organisations producing official statistics operate. Big Data provides opportunities, but in order to make optimal use of Big Data, a number of challenges have to be addressed. This stimulates increased collaboration between National Statistical Institutes, Big Data holders, businesses and universities. In time, this may lead to a shift in the role of statistical institutes in the provision of high-quality and impartial statistical information to society. In this paper, the changes in context, the opportunities, the challenges and the way to collaborate are addressed. The collaboration between the various stakeholders will involve each partner building on and contributing different strengths. For national statistical offices, traditional strengths include, on the one hand, the ability to collect data and combine data sources with statistical products and, on the other hand, their focus on quality, transparency and sound methodology. In the Big Data era of competing and multiplying data sources, they continue to have a unique knowledge of official statistical production methods. And their impartiality and respect for privacy as enshrined in law uniquely position them as a trusted third party. Based on this, they may advise on the quality and validity of information of various sources. By thus positioning themselves, they will be able to play their role as key information providers in a changing society.

  10. Big Data

    OpenAIRE

    Bútora, Matúš

    2017-01-01

    Cieľom bakalárskej práca je popísať problematiku Big Data a agregačné operácie OLAP pre podporu rozhodovania, ktoré sú na ne aplikované pomocou technológie Apache Hadoop. Prevažná časť práce je venovaná popisu práve tejto technológie. Posledná kapitola sa zaoberá spôsobom aplikovania agregačných operácií a problematikou ich realizácie. Nasleduje celkové zhodnotenie práce a možnosti využitia výsledného systému do budúcna. The aim of the bachelor thesis is to describe the Big Data issue and ...

  11. BigDansing

    KAUST Repository

    Khayyat, Zuhair; Ilyas, Ihab F.; Jindal, Alekh; Madden, Samuel; Ouzzani, Mourad; Papotti, Paolo; Quiané -Ruiz, Jorge-Arnulfo; Tang, Nan; Yin, Si

    2015-01-01

    of the underlying distributed platform. BigDansing takes these rules into a series of transformations that enable distributed computations and several optimizations, such as shared scans and specialized joins operators. Experimental results on both synthetic

  12. Leveraging Mobile Network Big Data for Developmental Policy ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Some argue that big data and big data users offer advantages to generate evidence. ... Supported by IDRC, this research focused on transportation planning in urban ... Using mobile network big data for land use classification CPRsouth 2015.

  13. Can greening of aquaculture sequester blue carbon?

    Science.gov (United States)

    Ahmed, Nesar; Bunting, Stuart W; Glaser, Marion; Flaherty, Mark S; Diana, James S

    2017-05-01

    Globally, blue carbon (i.e., carbon in coastal and marine ecosystems) emissions have been seriously augmented due to the devastating effects of anthropogenic pressures on coastal ecosystems including mangrove swamps, salt marshes, and seagrass meadows. The greening of aquaculture, however, including an ecosystem approach to Integrated Aquaculture-Agriculture (IAA) and Integrated Multi-Trophic Aquaculture (IMTA) could play a significant role in reversing this trend, enhancing coastal ecosystems, and sequestering blue carbon. Ponds within IAA farming systems sequester more carbon per unit area than conventional fish ponds, natural lakes, and inland seas. The translocation of shrimp culture from mangrove swamps to offshore IMTA could reduce mangrove loss, reverse blue carbon emissions, and in turn increase storage of blue carbon through restoration of mangroves. Moreover, offshore IMTA may create a barrier to trawl fishing which in turn could help restore seagrasses and further enhance blue carbon sequestration. Seaweed and shellfish culture within IMTA could also help to sequester more blue carbon. The greening of aquaculture could face several challenges that need to be addressed in order to realize substantial benefits from enhanced blue carbon sequestration and eventually contribute to global climate change mitigation.

  14. Practice Variation in Big-4 Transparency Reports

    DEFF Research Database (Denmark)

    Girdhar, Sakshi; Klarskov Jeppesen, Kim

    2018-01-01

    Purpose: The purpose of this paper is to examine the transparency reports published by the Big-4 public accounting firms in the UK, Germany and Denmark to understand the determinants of their content within the networks of big accounting firms. Design/methodology/approach: The study draws...... on a qualitative research approach, in which the content of transparency reports is analyzed and semi-structured interviews are conducted with key people from the Big-4 firms who are responsible for developing the transparency reports. Findings: The findings show that the content of transparency reports...... is inconsistent and the transparency reporting practice is not uniform within the Big-4 networks. Differences were found in the way in which the transparency reporting practices are coordinated globally by the respective central governing bodies of the Big-4. The content of the transparency reports...

  15. The fading of irradiated blue-colored pearls

    International Nuclear Information System (INIS)

    Okamoto, Shinichi

    1982-01-01

    The fading of irradiated and natural blue-colored pearls was investigated in this experiment. Thirty natural blue-colored pearls and sixty irradiated blue-colored pearls were used. Some of them were placed at a light position of RT. Another pearls were placed at a dark position of 50 0 C. The irradiated pearls placed at a light position of RT didn't show remarkable fading in their color in 294 days. But the natural blue-colored pearls showed a little recovery from 4% to 8% in reflection factors in 223 days at RT. The irradiated pearls placed at a dark position of 50 0 C showed the recovery from 9% to 14% in 264 days independently of irradiation times. The natural blue-colored pearls also showed the bleaching from 5% to 10% in reflection factor in 86 days at 50 0 C. Both irradiated and natural blue-colored pearls hardly showed their remarkable changes in their chromaticities independently of temperatures. (author)

  16. Blue space geographies: Enabling health in place.

    Science.gov (United States)

    Foley, Ronan; Kistemann, Thomas

    2015-09-01

    Drawing from research on therapeutic landscapes and relationships between environment, health and wellbeing, we propose the idea of 'healthy blue space' as an important new development Complementing research on healthy green space, blue space is defined as; 'health-enabling places and spaces, where water is at the centre of a range of environments with identifiable potential for the promotion of human wellbeing'. Using theoretical ideas from emotional and relational geographies and critical understandings of salutogenesis, the value of blue space to health and wellbeing is recognised and evaluated. Six individual papers from five different countries consider how health can be enabled in mixed blue space settings. Four sub-themes; embodiment, inter-subjectivity, activity and meaning, document multiple experiences within a range of healthy blue spaces. Finally, we suggest a considerable research agenda - theoretical, methodological and applied - for future work within different forms of blue space. All are suggested as having public health policy relevance in social and public space. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Big data and biomedical informatics: a challenging opportunity.

    Science.gov (United States)

    Bellazzi, R

    2014-05-22

    Big data are receiving an increasing attention in biomedicine and healthcare. It is therefore important to understand the reason why big data are assuming a crucial role for the biomedical informatics community. The capability of handling big data is becoming an enabler to carry out unprecedented research studies and to implement new models of healthcare delivery. Therefore, it is first necessary to deeply understand the four elements that constitute big data, namely Volume, Variety, Velocity, and Veracity, and their meaning in practice. Then, it is mandatory to understand where big data are present, and where they can be beneficially collected. There are research fields, such as translational bioinformatics, which need to rely on big data technologies to withstand the shock wave of data that is generated every day. Other areas, ranging from epidemiology to clinical care, can benefit from the exploitation of the large amounts of data that are nowadays available, from personal monitoring to primary care. However, building big data-enabled systems carries on relevant implications in terms of reproducibility of research studies and management of privacy and data access; proper actions should be taken to deal with these issues. An interesting consequence of the big data scenario is the availability of new software, methods, and tools, such as map-reduce, cloud computing, and concept drift machine learning algorithms, which will not only contribute to big data research, but may be beneficial in many biomedical informatics applications. The way forward with the big data opportunity will require properly applied engineering principles to design studies and applications, to avoid preconceptions or over-enthusiasms, to fully exploit the available technologies, and to improve data processing and data management regulations.

  18. Was the big bang hot

    International Nuclear Information System (INIS)

    Wright, E.L.

    1983-01-01

    The author considers experiments to confirm the substantial deviations from a Planck curve in the Woody and Richards spectrum of the microwave background, and search for conducting needles in our galaxy. Spectral deviations and needle-shaped grains are expected for a cold Big Bang, but are not required by a hot Big Bang. (Auth.)

  19. Passport to the Big Bang

    CERN Multimedia

    De Melis, Cinzia

    2013-01-01

    Le 2 juin 2013, le CERN inaugure le projet Passeport Big Bang lors d'un grand événement public. Affiche et programme. On 2 June 2013 CERN launches a scientific tourist trail through the Pays de Gex and the Canton of Geneva known as the Passport to the Big Bang. Poster and Programme.

  20. Starbursts in Blue compact dwarf galaxies

    International Nuclear Information System (INIS)

    Thuan, T.X.

    1987-01-01

    We summarize all the arguments for a bursting mode of star formation in blue compact dwarf galaxies. We show in particular how spectral synthesis of far ultraviolet spectra of Blue compact dwarf galaxy constitutes a powerful way for studying the star formation history in these galaxies. Blue compact dwarf galaxy luminosity functions show jumps and discontinuities. These jumps act like fossil records of the star-forming bursts, helping us to count and date the bursts

  1. Personalized medicine beyond genomics: alternative futures in big data-proteomics, environtome and the social proteome.

    Science.gov (United States)

    Özdemir, Vural; Dove, Edward S; Gürsoy, Ulvi K; Şardaş, Semra; Yıldırım, Arif; Yılmaz, Şenay Görücü; Ömer Barlas, I; Güngör, Kıvanç; Mete, Alper; Srivastava, Sanjeeva

    2017-01-01

    No field in science and medicine today remains untouched by Big Data, and psychiatry is no exception. Proteomics is a Big Data technology and a next generation biomarker, supporting novel system diagnostics and therapeutics in psychiatry. Proteomics technology is, in fact, much older than genomics and dates to the 1970s, well before the launch of the international Human Genome Project. While the genome has long been framed as the master or "elite" executive molecule in cell biology, the proteome by contrast is humble. Yet the proteome is critical for life-it ensures the daily functioning of cells and whole organisms. In short, proteins are the blue-collar workers of biology, the down-to-earth molecules that we cannot live without. Since 2010, proteomics has found renewed meaning and international attention with the launch of the Human Proteome Project and the growing interest in Big Data technologies such as proteomics. This article presents an interdisciplinary technology foresight analysis and conceptualizes the terms "environtome" and "social proteome". We define "environtome" as the entire complement of elements external to the human host, from microbiome, ambient temperature and weather conditions to government innovation policies, stock market dynamics, human values, political power and social norms that collectively shape the human host spatially and temporally. The "social proteome" is the subset of the environtome that influences the transition of proteomics technology to innovative applications in society. The social proteome encompasses, for example, new reimbursement schemes and business innovation models for proteomics diagnostics that depart from the "once-a-life-time" genotypic tests and the anticipated hype attendant to context and time sensitive proteomics tests. Building on the "nesting principle" for governance of complex systems as discussed by Elinor Ostrom, we propose here a 3-tiered organizational architecture for Big Data science such as

  2. Hubble's View of Little Blue Dots

    Science.gov (United States)

    Kohler, Susanna

    2018-02-01

    The recent discovery of a new type of tiny, star-forming galaxy is the latest in a zoo of detections shedding light on our early universe. What can we learn from the unique little blue dots found in archival Hubble data?Peas, Berries, and DotsGreen pea galaxies identified by citizen scientists with Galaxy Zoo. [Richard Nowell Carolin Cardamone]As telescope capabilities improve and we develop increasingly deeper large-scale surveys of our universe, we continue to learn more about small, faraway galaxies. In recent years, increasing sensitivity first enabled the detection of green peas luminous, compact, low-mass (10 billion solar masses; compare this to the Milky Ways 1 trillion solar masses!) galaxies with high rates of star formation.Not long thereafter, we discovered galaxies that form stars similarly rapidly, but are even smaller only 330 million solar masses, spanning less than 3,000 light-years in size. These tiny powerhouses were termed blueberries for their distinctive color.Now, scientists Debra and Bruce Elmegreen (of Vassar College and IBM Research Division, respectively) report the discovery of galaxies that have even higher star formation rates and even lower masses: little blue dots.Exploring Tiny Star FactoriesThe Elmegreens discovered these unique galaxies by exploring archival Hubble data. The Hubble Frontier Fields data consist of deep images of six distant galaxy clusters and the parallel fields next to them. It was in the archival data for two Frontier Field Parallels, those for clusters Abell 2744 and MAS J0416.1-2403, that the authors noticed several galaxies that stand out as tiny, bright, blue objects that are nearly point sources.Top: a few examples of the little blue dots recently identified in two Hubble Frontier Field Parallels. Bottom: stacked images for three different groups of little blue dots. [Elmegreen Elmegreen 2017]The authors performed a search through the two Frontier Field Parallels, discovering a total of 55 little blue dots

  3. Keynote: Big Data, Big Opportunities

    OpenAIRE

    Borgman, Christine L.

    2014-01-01

    The enthusiasm for big data is obscuring the complexity and diversity of data in scholarship and the challenges for stewardship. Inside the black box of data are a plethora of research, technology, and policy issues. Data are not shiny objects that are easily exchanged. Rather, data are representations of observations, objects, or other entities used as evidence of phenomena for the purposes of research or scholarship. Data practices are local, varying from field to field, individual to indiv...

  4. Integrating R and Hadoop for Big Data Analysis

    OpenAIRE

    Bogdan Oancea; Raluca Mariana Dragoescu

    2014-01-01

    Analyzing and working with big data could be very diffi cult using classical means like relational database management systems or desktop software packages for statistics and visualization. Instead, big data requires large clusters with hundreds or even thousands of computing nodes. Offi cial statistics is increasingly considering big data for deriving new statistics because big data sources could produce more relevant and timely statistics than traditional sources. One of the software tools ...

  5. The challenges of big data.

    Science.gov (United States)

    Mardis, Elaine R

    2016-05-01

    The largely untapped potential of big data analytics is a feeding frenzy that has been fueled by the production of many next-generation-sequencing-based data sets that are seeking to answer long-held questions about the biology of human diseases. Although these approaches are likely to be a powerful means of revealing new biological insights, there are a number of substantial challenges that currently hamper efforts to harness the power of big data. This Editorial outlines several such challenges as a means of illustrating that the path to big data revelations is paved with perils that the scientific community must overcome to pursue this important quest. © 2016. Published by The Company of Biologists Ltd.

  6. Big³. Editorial.

    Science.gov (United States)

    Lehmann, C U; Séroussi, B; Jaulent, M-C

    2014-05-22

    To provide an editorial introduction into the 2014 IMIA Yearbook of Medical Informatics with an overview of the content, the new publishing scheme, and upcoming 25th anniversary. A brief overview of the 2014 special topic, Big Data - Smart Health Strategies, and an outline of the novel publishing model is provided in conjunction with a call for proposals to celebrate the 25th anniversary of the Yearbook. 'Big Data' has become the latest buzzword in informatics and promise new approaches and interventions that can improve health, well-being, and quality of life. This edition of the Yearbook acknowledges the fact that we just started to explore the opportunities that 'Big Data' will bring. However, it will become apparent to the reader that its pervasive nature has invaded all aspects of biomedical informatics - some to a higher degree than others. It was our goal to provide a comprehensive view at the state of 'Big Data' today, explore its strengths and weaknesses, as well as its risks, discuss emerging trends, tools, and applications, and stimulate the development of the field through the aggregation of excellent survey papers and working group contributions to the topic. For the first time in history will the IMIA Yearbook be published in an open access online format allowing a broader readership especially in resource poor countries. For the first time, thanks to the online format, will the IMIA Yearbook be published twice in the year, with two different tracks of papers. We anticipate that the important role of the IMIA yearbook will further increase with these changes just in time for its 25th anniversary in 2016.

  7. Cloud Based Big Data Infrastructure: Architectural Components and Automated Provisioning

    OpenAIRE

    Demchenko, Yuri; Turkmen, Fatih; Blanchet, Christophe; Loomis, Charles; Laat, Caees de

    2016-01-01

    This paper describes the general architecture and functional components of the cloud based Big Data Infrastructure (BDI). The proposed BDI architecture is based on the analysis of the emerging Big Data and data intensive technologies and supported by the definition of the Big Data Architecture Framework (BDAF) that defines the following components of the Big Data technologies: Big Data definition, Data Management including data lifecycle and data structures, Big Data Infrastructure (generical...

  8. Physics with Big Karl Brainstorming. Abstracts

    International Nuclear Information System (INIS)

    Machner, H.; Lieb, J.

    2000-08-01

    Before summarizing details of the meeting, a short description of the spectrometer facility Big Karl is given. The facility is essentially a new instrument using refurbished dipole magnets from its predecessor. The large acceptance quadrupole magnets and the beam optics are new. Big Karl has a design very similar as the focussing spectrometers at MAMI (Mainz), AGOR (Groningen) and the high resolution spectrometer (HRS) in Hall A at Jefferson Laboratory with ΔE/E = 10 -4 but at some lower maximum momentum. The focal plane detectors consisting of multiwire drift chambers and scintillating hodoscopes are similar. Unlike HRS, Big Karl still needs Cerenkov counters and polarimeters in its focal plane; detectors which are necessary to perform some of the experiments proposed during the brainstorming. In addition, BIG KARL allows emission angle reconstruction via track measurements in its focal plane with high resolution. In the following the physics highlights, the proposed and potential experiments are summarized. During the meeting it became obvious that the physics to be explored at Big Karl can be grouped into five distinct categories, and this summary is organized accordingly. (orig.)

  9. Variable blue straggler stars in NGC 5466

    International Nuclear Information System (INIS)

    Harris, H.C.; Mateo, M.; Olszewski, E.W.; Nemec, J.M.

    1990-01-01

    Nine variable blue stragglers have been found in the globular cluster NGC 5466. The six dwarf Cepheids in this cluster coexist in the instability strip with other nonvariable stars. The three eclipsing binaries are among the hottest of the blue stragglers. The hypothesis is discussed that all blue stragglers in this cluster have undergone mass transfer in close binaries. Under this hypothesis, rotation and spin-down play important roles in controlling the evolution of blue stragglers in old clusters and in affecting some of their observational properties. 14 refs

  10. Seed bank and big sagebrush plant community composition in a range margin for big sagebrush

    Science.gov (United States)

    Martyn, Trace E.; Bradford, John B.; Schlaepfer, Daniel R.; Burke, Ingrid C.; Laurenroth, William K.

    2016-01-01

    The potential influence of seed bank composition on range shifts of species due to climate change is unclear. Seed banks can provide a means of both species persistence in an area and local range expansion in the case of increasing habitat suitability, as may occur under future climate change. However, a mismatch between the seed bank and the established plant community may represent an obstacle to persistence and expansion. In big sagebrush (Artemisia tridentata) plant communities in Montana, USA, we compared the seed bank to the established plant community. There was less than a 20% similarity in the relative abundance of species between the established plant community and the seed bank. This difference was primarily driven by an overrepresentation of native annual forbs and an underrepresentation of big sagebrush in the seed bank compared to the established plant community. Even though we expect an increase in habitat suitability for big sagebrush under future climate conditions at our sites, the current mismatch between the plant community and the seed bank could impede big sagebrush range expansion into increasingly suitable habitat in the future.

  11. Application and Prospect of Big Data in Water Resources

    Science.gov (United States)

    Xi, Danchi; Xu, Xinyi

    2017-04-01

    Because of developed information technology and affordable data storage, we h ave entered the era of data explosion. The term "Big Data" and technology relate s to it has been created and commonly applied in many fields. However, academic studies just got attention on Big Data application in water resources recently. As a result, water resource Big Data technology has not been fully developed. This paper introduces the concept of Big Data and its key technologies, including the Hadoop system and MapReduce. In addition, this paper focuses on the significance of applying the big data in water resources and summarizing prior researches by others. Most studies in this field only set up theoretical frame, but we define the "Water Big Data" and explain its tridimensional properties which are time dimension, spatial dimension and intelligent dimension. Based on HBase, the classification system of Water Big Data is introduced: hydrology data, ecology data and socio-economic data. Then after analyzing the challenges in water resources management, a series of solutions using Big Data technologies such as data mining and web crawler, are proposed. Finally, the prospect of applying big data in water resources is discussed, it can be predicted that as Big Data technology keeps developing, "3D" (Data Driven Decision) will be utilized more in water resources management in the future.

  12. Big Data in food and agriculture

    Directory of Open Access Journals (Sweden)

    Kelly Bronson

    2016-06-01

    Full Text Available Farming is undergoing a digital revolution. Our existing review of current Big Data applications in the agri-food sector has revealed several collection and analytics tools that may have implications for relationships of power between players in the food system (e.g. between farmers and large corporations. For example, Who retains ownership of the data generated by applications like Monsanto Corproation's Weed I.D . “app”? Are there privacy implications with the data gathered by John Deere's precision agricultural equipment? Systematically tracing the digital revolution in agriculture, and charting the affordances as well as the limitations of Big Data applied to food and agriculture, should be a broad research goal for Big Data scholarship. Such a goal brings data scholarship into conversation with food studies and it allows for a focus on the material consequences of big data in society.

  13. Big data optimization recent developments and challenges

    CERN Document Server

    2016-01-01

    The main objective of this book is to provide the necessary background to work with big data by introducing some novel optimization algorithms and codes capable of working in the big data setting as well as introducing some applications in big data optimization for both academics and practitioners interested, and to benefit society, industry, academia, and government. Presenting applications in a variety of industries, this book will be useful for the researchers aiming to analyses large scale data. Several optimization algorithms for big data including convergent parallel algorithms, limited memory bundle algorithm, diagonal bundle method, convergent parallel algorithms, network analytics, and many more have been explored in this book.

  14. Una aproximación a Big Data = An approach to Big Data

    OpenAIRE

    Puyol Moreno, Javier

    2014-01-01

    Big Data puede ser considerada como una tendencia en el avance de la tecnología que ha abierto la puerta a un nuevo enfoque para la comprensión y la toma de decisiones, que se utiliza para describir las enormes cantidades de datos (estructurados, no estructurados y semi- estructurados) que sería demasiado largo y costoso para cargar una base de datos relacional para su análisis. Así, el concepto de Big Data se aplica a toda la información que no puede ser procesada o analizada utilizando herr...

  15. Toward a Literature-Driven Definition of Big Data in Healthcare.

    Science.gov (United States)

    Baro, Emilie; Degoul, Samuel; Beuscart, Régis; Chazard, Emmanuel

    2015-01-01

    The aim of this study was to provide a definition of big data in healthcare. A systematic search of PubMed literature published until May 9, 2014, was conducted. We noted the number of statistical individuals (n) and the number of variables (p) for all papers describing a dataset. These papers were classified into fields of study. Characteristics attributed to big data by authors were also considered. Based on this analysis, a definition of big data was proposed. A total of 196 papers were included. Big data can be defined as datasets with Log(n∗p) ≥ 7. Properties of big data are its great variety and high velocity. Big data raises challenges on veracity, on all aspects of the workflow, on extracting meaningful information, and on sharing information. Big data requires new computational methods that optimize data management. Related concepts are data reuse, false knowledge discovery, and privacy issues. Big data is defined by volume. Big data should not be confused with data reuse: data can be big without being reused for another purpose, for example, in omics. Inversely, data can be reused without being necessarily big, for example, secondary use of Electronic Medical Records (EMR) data.

  16. Big Data Analytic, Big Step for Patient Management and Care in Puerto Rico.

    Science.gov (United States)

    Borrero, Ernesto E

    2018-01-01

    This letter provides an overview of the application of big data in health care system to improve quality of care, including predictive modelling for risk and resource use, precision medicine and clinical decision support, quality of care and performance measurement, public health and research applications, among others. The author delineates the tremendous potential for big data analytics and discuss how it can be successfully implemented in clinical practice, as an important component of a learning health-care system.

  17. Molecular evidence for the subspecific differentiation of blue sheep (Pseudois nayaur) and polyphyletic origin of dwarf blue sheep (Pseudois schaeferi).

    Science.gov (United States)

    Tan, Shuai; Zou, Dandan; Tang, Lei; Wang, Gaochao; Peng, Quekun; Zeng, Bo; Zhang, Chen; Zou, Fangdong

    2012-06-01

    Blue sheep (Pseudois nayaur), a Central Asian ungulate with restricted geographic distribution, exhibits unclear variation in morphology and phylogeographic structure. The composition of species and subspecies in the genus Pseudois is controversial, particularly with respect to the taxonomic designation of geographically restricted populations. Here, 26 specimens including 5 dwarf blue sheep (Pseudois schaeferi), which were collected from a broad geographic region in China, were analyzed for 2 mitochondrial DNA fragments (cytochrome b and control region sequences). In a pattern consistent with geographically defined subspecies, we found three deeply divergent mitochondrial lineages restricted to different geographic regions. The currently designated two subspecies of blue sheep, Pseudois nayaur nayaur and Pseudois nayaur szechuanensis, were recognized in the phylogenetic trees. In addition, the Helan Mountain population showed distinct genetic characteristics from other geographic populations, and thus should be classified as a new subspecies. In contrast, dwarf blue sheep clustered closely with some blue sheep from Sichuan Province in the phylogenetic trees. Therefore, dwarf blue sheep appear to be a subset of Pseudois nayaur szechuanensis. After considering both population genetic information and molecular clock analysis, we obtained some relevant molecular phylogeographic information concerning the historical biogeography of blue sheep. These results also indicate that western Sichuan was a potential refugium for blue sheep during the Quaternary period.

  18. Big Data and Biomedical Informatics: A Challenging Opportunity

    Science.gov (United States)

    2014-01-01

    Summary Big data are receiving an increasing attention in biomedicine and healthcare. It is therefore important to understand the reason why big data are assuming a crucial role for the biomedical informatics community. The capability of handling big data is becoming an enabler to carry out unprecedented research studies and to implement new models of healthcare delivery. Therefore, it is first necessary to deeply understand the four elements that constitute big data, namely Volume, Variety, Velocity, and Veracity, and their meaning in practice. Then, it is mandatory to understand where big data are present, and where they can be beneficially collected. There are research fields, such as translational bioinformatics, which need to rely on big data technologies to withstand the shock wave of data that is generated every day. Other areas, ranging from epidemiology to clinical care, can benefit from the exploitation of the large amounts of data that are nowadays available, from personal monitoring to primary care. However, building big data-enabled systems carries on relevant implications in terms of reproducibility of research studies and management of privacy and data access; proper actions should be taken to deal with these issues. An interesting consequence of the big data scenario is the availability of new software, methods, and tools, such as map-reduce, cloud computing, and concept drift machine learning algorithms, which will not only contribute to big data research, but may be beneficial in many biomedical informatics applications. The way forward with the big data opportunity will require properly applied engineering principles to design studies and applications, to avoid preconceptions or over-enthusiasms, to fully exploit the available technologies, and to improve data processing and data management regulations. PMID:24853034

  19. Big data governance an emerging imperative

    CERN Document Server

    Soares, Sunil

    2012-01-01

    Written by a leading expert in the field, this guide focuses on the convergence of two major trends in information management-big data and information governance-by taking a strategic approach oriented around business cases and industry imperatives. With the advent of new technologies, enterprises are expanding and handling very large volumes of data; this book, nontechnical in nature and geared toward business audiences, encourages the practice of establishing appropriate governance over big data initiatives and addresses how to manage and govern big data, highlighting the relevant processes,

  20. Big Data and historical social science

    Directory of Open Access Journals (Sweden)

    Peter Bearman

    2015-11-01

    Full Text Available “Big Data” can revolutionize historical social science if it arises from substantively important contexts and is oriented towards answering substantively important questions. Such data may be especially important for answering previously largely intractable questions about the timing and sequencing of events, and of event boundaries. That said, “Big Data” makes no difference for social scientists and historians whose accounts rest on narrative sentences. Since such accounts are the norm, the effects of Big Data on the practice of historical social science may be more limited than one might wish.

  1. The Inverted Big-Bang

    OpenAIRE

    Vaas, Ruediger

    2004-01-01

    Our universe appears to have been created not out of nothing but from a strange space-time dust. Quantum geometry (loop quantum gravity) makes it possible to avoid the ominous beginning of our universe with its physically unrealistic (i.e. infinite) curvature, extreme temperature, and energy density. This could be the long sought after explanation of the big-bang and perhaps even opens a window into a time before the big-bang: Space itself may have come from an earlier collapsing universe tha...

  2. Minsky on "Big Government"

    Directory of Open Access Journals (Sweden)

    Daniel de Santana Vasconcelos

    2014-03-01

    Full Text Available This paper objective is to assess, in light of the main works of Minsky, his view and analysis of what he called the "Big Government" as that huge institution which, in parallels with the "Big Bank" was capable of ensuring stability in the capitalist system and regulate its inherently unstable financial system in mid-20th century. In this work, we analyze how Minsky proposes an active role for the government in a complex economic system flawed by financial instability.

  3. Relatively high rates of G:C → A:T transitions at CpG sites were observed in certain epithelial tissues including pancreas and submaxillary gland of adult big blue® mice.

    Science.gov (United States)

    Prtenjaca, Anita; Tarnowski, Heather E; Marr, Alison M; Heney, Melanie A; Creamer, Laura; Sathiamoorthy, Sarmitha; Hill, Kathleen A

    2014-01-01

    With few exceptions, spontaneous mutation frequency and pattern are similar across tissue types and relatively constant in young to middle adulthood in wild type mice. Underrepresented in surveys of spontaneous mutations across murine tissues is the diversity of epithelial tissues. For the first time, spontaneous mutations were detected in pancreas and submaxillary gland and compared with kidney, lung, and male germ cells from five adult male Big Blue® mice. Mutation load was assessed quantitatively through measurement of mutant and mutation frequency and qualitatively through identification of mutations and characterization of recurrent mutations, multiple mutations, mutation pattern, and mutation spectrum. A total of 9.6 million plaque forming units were screened, 226 mutants were collected, and 196 independent mutations were identified. Four novel mutations were discovered. Spontaneous mutation frequency was low in pancreas and high in the submaxillary gland. The submaxillary gland had multiple recurrent mutations in each of the mice and one mutant had two independent mutations. Mutation patterns for epithelial tissues differed from that observed in male germ cells with a striking bias for G:C to A:T transitions at CpG sites. A comprehensive review of lacI spontaneous mutation patterns in young adult mice and rats identified additional examples of this mutational bias. An overarching observation about spontaneous mutation frequency in adult tissues of the mouse remains one of stability. A repeated observation in certain epithelial tissues is a higher rate of G:C to A:T transitions at CpG sites and the underlying mechanisms for this bias are not known. Copyright © 2013 Wiley Periodicals, Inc.

  4. The discrimination of (non-denim) blue cotton.

    Science.gov (United States)

    Palmer, Ray; Hutchinson, William; Fryer, Verity

    2009-03-01

    This study was conducted to determine the degree of discrimination obtained between non-denim blue cotton fibres using visible-UV range microspectrophotometry alone. To this end, samples of fibres were taken from 100, nondenim, blue cotton, outer garments, including t-shirts, trousers and jumpers and subjected to analysis by both visible and UV range microspectrophotometry. The results obtained from the samples of each garment were compared to determine if they 'matched' or not. From an initial visual comparison of the garments it was possible to subdivide the samples into two populations consisting of 73 'dark blue' garments and 27 'mid-blue' garments. It was found that of the 73 'dark blue' garments, 22 distinct sub-populations could be distinguished using visible range MSP, this figure being increased to 43 when the analysis was extended into the UVW range. In the case of the 27 'mid-blue' garments, 9 distinct sub-populations were discriminated using visible range MSP, this figure being increased to 17 when the analysis was extended into the UV range. The discriminating power (i.e., the number of discriminated pairs divided by the number of possible pairs) of visible range microspectrophotometry was calculated as 0.89 for 'mid-blue' garments and 0.87 for 'dark blue' garments. Extending microspectrophotometry into the UV range increased discrimination by 7%, giving a discriminating power of 0.96 for both mid and dark blue cotton fibres which was similar to that reported by a previous study where this method was combined with light and fluorescence microscopy. Intra-garment variation was found to be negligible. The implications of this study for casework are discussed and a revised analytical pathway for the comparison of this fibre type/colour combination using microspectrophotometry as a primary screening tool, is proposed.

  5. The Information Panopticon in the Big Data Era

    Directory of Open Access Journals (Sweden)

    Martin Berner

    2014-04-01

    Full Text Available Taking advantage of big data opportunities is challenging for traditional organizations. In this article, we take a panoptic view of big data – obtaining information from more sources and making it visible to all organizational levels. We suggest that big data requires the transformation from command and control hierarchies to post-bureaucratic organizational structures wherein employees at all levels can be empowered while simultaneously being controlled. We derive propositions that show how to best exploit big data technologies in organizations.

  6. WE-H-BRB-00: Big Data in Radiation Oncology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    Big Data in Radiation Oncology: (1) Overview of the NIH 2015 Big Data Workshop, (2) Where do we stand in the applications of big data in radiation oncology?, and (3) Learning Health Systems for Radiation Oncology: Needs and Challenges for Future Success The overriding goal of this trio panel of presentations is to improve awareness of the wide ranging opportunities for big data impact on patient quality care and enhancing potential for research and collaboration opportunities with NIH and a host of new big data initiatives. This presentation will also summarize the Big Data workshop that was held at the NIH Campus on August 13–14, 2015 and sponsored by AAPM, ASTRO, and NIH. The workshop included discussion of current Big Data cancer registry initiatives, safety and incident reporting systems, and other strategies that will have the greatest impact on radiation oncology research, quality assurance, safety, and outcomes analysis. Learning Objectives: To discuss current and future sources of big data for use in radiation oncology research To optimize our current data collection by adopting new strategies from outside radiation oncology To determine what new knowledge big data can provide for clinical decision support for personalized medicine L. Xing, NIH/NCI Google Inc.

  7. WE-H-BRB-00: Big Data in Radiation Oncology

    International Nuclear Information System (INIS)

    2016-01-01

    Big Data in Radiation Oncology: (1) Overview of the NIH 2015 Big Data Workshop, (2) Where do we stand in the applications of big data in radiation oncology?, and (3) Learning Health Systems for Radiation Oncology: Needs and Challenges for Future Success The overriding goal of this trio panel of presentations is to improve awareness of the wide ranging opportunities for big data impact on patient quality care and enhancing potential for research and collaboration opportunities with NIH and a host of new big data initiatives. This presentation will also summarize the Big Data workshop that was held at the NIH Campus on August 13–14, 2015 and sponsored by AAPM, ASTRO, and NIH. The workshop included discussion of current Big Data cancer registry initiatives, safety and incident reporting systems, and other strategies that will have the greatest impact on radiation oncology research, quality assurance, safety, and outcomes analysis. Learning Objectives: To discuss current and future sources of big data for use in radiation oncology research To optimize our current data collection by adopting new strategies from outside radiation oncology To determine what new knowledge big data can provide for clinical decision support for personalized medicine L. Xing, NIH/NCI Google Inc.

  8. De impact van Big Data op Internationale Betrekkingen

    NARCIS (Netherlands)

    Zwitter, Andrej

    Big Data changes our daily lives, but does it also change international politics? In this contribution, Andrej Zwitter (NGIZ chair at Groningen University) argues that Big Data impacts on international relations in ways that we only now start to understand. To comprehend how Big Data influences

  9. Epidemiology in the Era of Big Data

    Science.gov (United States)

    Mooney, Stephen J; Westreich, Daniel J; El-Sayed, Abdulrahman M

    2015-01-01

    Big Data has increasingly been promoted as a revolutionary development in the future of science, including epidemiology. However, the definition and implications of Big Data for epidemiology remain unclear. We here provide a working definition of Big Data predicated on the so-called ‘3 Vs’: variety, volume, and velocity. From this definition, we argue that Big Data has evolutionary and revolutionary implications for identifying and intervening on the determinants of population health. We suggest that as more sources of diverse data become publicly available, the ability to combine and refine these data to yield valid answers to epidemiologic questions will be invaluable. We conclude that, while epidemiology as practiced today will continue to be practiced in the Big Data future, a component of our field’s future value lies in integrating subject matter knowledge with increased technical savvy. Our training programs and our visions for future public health interventions should reflect this future. PMID:25756221

  10. BLUES function method in computational physics

    Science.gov (United States)

    Indekeu, Joseph O.; Müller-Nedebock, Kristian K.

    2018-04-01

    We introduce a computational method in physics that goes ‘beyond linear use of equation superposition’ (BLUES). A BLUES function is defined as a solution of a nonlinear differential equation (DE) with a delta source that is at the same time a Green’s function for a related linear DE. For an arbitrary source, the BLUES function can be used to construct an exact solution to the nonlinear DE with a different, but related source. Alternatively, the BLUES function can be used to construct an approximate piecewise analytical solution to the nonlinear DE with an arbitrary source. For this alternative use the related linear DE need not be known. The method is illustrated in a few examples using analytical calculations and numerical computations. Areas for further applications are suggested.

  11. Big data and analytics strategic and organizational impacts

    CERN Document Server

    Morabito, Vincenzo

    2015-01-01

    This book presents and discusses the main strategic and organizational challenges posed by Big Data and analytics in a manner relevant to both practitioners and scholars. The first part of the book analyzes strategic issues relating to the growing relevance of Big Data and analytics for competitive advantage, which is also attributable to empowerment of activities such as consumer profiling, market segmentation, and development of new products or services. Detailed consideration is also given to the strategic impact of Big Data and analytics on innovation in domains such as government and education and to Big Data-driven business models. The second part of the book addresses the impact of Big Data and analytics on management and organizations, focusing on challenges for governance, evaluation, and change management, while the concluding part reviews real examples of Big Data and analytics innovation at the global level. The text is supported by informative illustrations and case studies, so that practitioners...

  12. Big Science and Long-tail Science

    CERN Document Server

    2008-01-01

    Jim Downing and I were privileged to be the guests of Salavtore Mele at CERN yesterday and to see the Atlas detector of the Large Hadron Collider . This is a wow experience - although I knew it was big, I hadnt realised how big.

  13. Toward a Literature-Driven Definition of Big Data in Healthcare

    Directory of Open Access Journals (Sweden)

    Emilie Baro

    2015-01-01

    Full Text Available Objective. The aim of this study was to provide a definition of big data in healthcare. Methods. A systematic search of PubMed literature published until May 9, 2014, was conducted. We noted the number of statistical individuals (n and the number of variables (p for all papers describing a dataset. These papers were classified into fields of study. Characteristics attributed to big data by authors were also considered. Based on this analysis, a definition of big data was proposed. Results. A total of 196 papers were included. Big data can be defined as datasets with Log⁡(n*p≥7. Properties of big data are its great variety and high velocity. Big data raises challenges on veracity, on all aspects of the workflow, on extracting meaningful information, and on sharing information. Big data requires new computational methods that optimize data management. Related concepts are data reuse, false knowledge discovery, and privacy issues. Conclusion. Big data is defined by volume. Big data should not be confused with data reuse: data can be big without being reused for another purpose, for example, in omics. Inversely, data can be reused without being necessarily big, for example, secondary use of Electronic Medical Records (EMR data.

  14. Toward a Literature-Driven Definition of Big Data in Healthcare

    Science.gov (United States)

    Baro, Emilie; Degoul, Samuel; Beuscart, Régis; Chazard, Emmanuel

    2015-01-01

    Objective. The aim of this study was to provide a definition of big data in healthcare. Methods. A systematic search of PubMed literature published until May 9, 2014, was conducted. We noted the number of statistical individuals (n) and the number of variables (p) for all papers describing a dataset. These papers were classified into fields of study. Characteristics attributed to big data by authors were also considered. Based on this analysis, a definition of big data was proposed. Results. A total of 196 papers were included. Big data can be defined as datasets with Log⁡(n∗p) ≥ 7. Properties of big data are its great variety and high velocity. Big data raises challenges on veracity, on all aspects of the workflow, on extracting meaningful information, and on sharing information. Big data requires new computational methods that optimize data management. Related concepts are data reuse, false knowledge discovery, and privacy issues. Conclusion. Big data is defined by volume. Big data should not be confused with data reuse: data can be big without being reused for another purpose, for example, in omics. Inversely, data can be reused without being necessarily big, for example, secondary use of Electronic Medical Records (EMR) data. PMID:26137488

  15. Big-Eyed Bugs Have Big Appetite for Pests

    Science.gov (United States)

    Many kinds of arthropod natural enemies (predators and parasitoids) inhabit crop fields in Arizona and can have a large negative impact on several pest insect species that also infest these crops. Geocoris spp., commonly known as big-eyed bugs, are among the most abundant insect predators in field c...

  16. Big Data - What is it and why it matters.

    Science.gov (United States)

    Tattersall, Andy; Grant, Maria J

    2016-06-01

    Big data, like MOOCs, altmetrics and open access, is a term that has been commonplace in the library community for some time yet, despite its prevalence, many in the library and information sector remain unsure of the relationship between big data and their roles. This editorial explores what big data could mean for the day-to-day practice of health library and information workers, presenting examples of big data in action, considering the ethics of accessing big data sets and the potential for new roles for library and information workers. © 2016 Health Libraries Group.

  17. Research on information security in big data era

    Science.gov (United States)

    Zhou, Linqi; Gu, Weihong; Huang, Cheng; Huang, Aijun; Bai, Yongbin

    2018-05-01

    Big data is becoming another hotspot in the field of information technology after the cloud computing and the Internet of Things. However, the existing information security methods can no longer meet the information security requirements in the era of big data. This paper analyzes the challenges and a cause of data security brought by big data, discusses the development trend of network attacks under the background of big data, and puts forward my own opinions on the development of security defense in technology, strategy and product.

  18. BIG DATA IN BUSINESS ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Logica BANICA

    2015-06-01

    Full Text Available In recent years, dealing with a lot of data originating from social media sites and mobile communications among data from business environments and institutions, lead to the definition of a new concept, known as Big Data. The economic impact of the sheer amount of data produced in a last two years has increased rapidly. It is necessary to aggregate all types of data (structured and unstructured in order to improve current transactions, to develop new business models, to provide a real image of the supply and demand and thereby, generate market advantages. So, the companies that turn to Big Data have a competitive advantage over other firms. Looking from the perspective of IT organizations, they must accommodate the storage and processing Big Data, and provide analysis tools that are easily integrated into business processes. This paper aims to discuss aspects regarding the Big Data concept, the principles to build, organize and analyse huge datasets in the business environment, offering a three-layer architecture, based on actual software solutions. Also, the article refers to the graphical tools for exploring and representing unstructured data, Gephi and NodeXL.

  19. Fuzzy 2-partition entropy threshold selection based on Big Bang–Big Crunch Optimization algorithm

    Directory of Open Access Journals (Sweden)

    Baljit Singh Khehra

    2015-03-01

    Full Text Available The fuzzy 2-partition entropy approach has been widely used to select threshold value for image segmenting. This approach used two parameterized fuzzy membership functions to form a fuzzy 2-partition of the image. The optimal threshold is selected by searching an optimal combination of parameters of the membership functions such that the entropy of fuzzy 2-partition is maximized. In this paper, a new fuzzy 2-partition entropy thresholding approach based on the technology of the Big Bang–Big Crunch Optimization (BBBCO is proposed. The new proposed thresholding approach is called the BBBCO-based fuzzy 2-partition entropy thresholding algorithm. BBBCO is used to search an optimal combination of parameters of the membership functions for maximizing the entropy of fuzzy 2-partition. BBBCO is inspired by the theory of the evolution of the universe; namely the Big Bang and Big Crunch Theory. The proposed algorithm is tested on a number of standard test images. For comparison, three different algorithms included Genetic Algorithm (GA-based, Biogeography-based Optimization (BBO-based and recursive approaches are also implemented. From experimental results, it is observed that the performance of the proposed algorithm is more effective than GA-based, BBO-based and recursion-based approaches.

  20. A little big history of Tiananmen

    NARCIS (Netherlands)

    Quaedackers, E.; Grinin, L.E.; Korotayev, A.V.; Rodrigue, B.H.

    2011-01-01

    This contribution aims at demonstrating the usefulness of studying small-scale subjects such as Tiananmen, or the Gate of Heavenly Peace, in Beijing - from a Big History perspective. By studying such a ‘little big history’ of Tiananmen, previously overlooked yet fundamental explanations for why

  1. Addressing big data issues in Scientific Data Infrastructure

    NARCIS (Netherlands)

    Demchenko, Y.; Membrey, P.; Grosso, P.; de Laat, C.; Smari, W.W.; Fox, G.C.

    2013-01-01

    Big Data are becoming a new technology focus both in science and in industry. This paper discusses the challenges that are imposed by Big Data on the modern and future Scientific Data Infrastructure (SDI). The paper discusses a nature and definition of Big Data that include such features as Volume,

  2. Improving Healthcare Using Big Data Analytics

    Directory of Open Access Journals (Sweden)

    Revanth Sonnati

    2017-03-01

    Full Text Available In daily terms we call the current era as Modern Era which can also be named as the era of Big Data in the field of Information Technology. Our daily lives in todays world are rapidly advancing never quenching ones thirst. The fields of science engineering and technology are producing data at an exponential rate leading to Exabytes of data every day. Big data helps us to explore and re-invent many areas not limited to education health and law. The primary purpose of this paper is to provide an in-depth analysis in the area of Healthcare using the big data and analytics. The main purpose is to emphasize on the usage of the big data which is being stored all the time helping to look back in the history but this is the time to emphasize on the analyzation to improve the medication and services. Although many big data implementations happen to be in-house development this proposed implementation aims to propose a broader extent using Hadoop which just happen to be the tip of the iceberg. The focus of this paper is not limited to the improvement and analysis of the data it also focusses on the strengths and drawbacks compared to the conventional techniques available.

  3. Big Data - Smart Health Strategies

    Science.gov (United States)

    2014-01-01

    Summary Objectives To select best papers published in 2013 in the field of big data and smart health strategies, and summarize outstanding research efforts. Methods A systematic search was performed using two major bibliographic databases for relevant journal papers. The references obtained were reviewed in a two-stage process, starting with a blinded review performed by the two section editors, and followed by a peer review process operated by external reviewers recognized as experts in the field. Results The complete review process selected four best papers, illustrating various aspects of the special theme, among them: (a) using large volumes of unstructured data and, specifically, clinical notes from Electronic Health Records (EHRs) for pharmacovigilance; (b) knowledge discovery via querying large volumes of complex (both structured and unstructured) biological data using big data technologies and relevant tools; (c) methodologies for applying cloud computing and big data technologies in the field of genomics, and (d) system architectures enabling high-performance access to and processing of large datasets extracted from EHRs. Conclusions The potential of big data in biomedicine has been pinpointed in various viewpoint papers and editorials. The review of current scientific literature illustrated a variety of interesting methods and applications in the field, but still the promises exceed the current outcomes. As we are getting closer towards a solid foundation with respect to common understanding of relevant concepts and technical aspects, and the use of standardized technologies and tools, we can anticipate to reach the potential that big data offer for personalized medicine and smart health strategies in the near future. PMID:25123721

  4. About Big Data and its Challenges and Benefits in Manufacturing

    OpenAIRE

    Bogdan NEDELCU

    2013-01-01

    The aim of this article is to show the importance of Big Data and its growing influence on companies. It also shows what kind of big data is currently generated and how much big data is estimated to be generated. We can also see how much are the companies willing to invest in big data and how much are they currently gaining from their big data. There are also shown some major influences that big data has over one major segment in the industry (manufacturing) and the challenges that appear.

  5. Big Data Management in US Hospitals: Benefits and Barriers.

    Science.gov (United States)

    Schaeffer, Chad; Booton, Lawrence; Halleck, Jamey; Studeny, Jana; Coustasse, Alberto

    Big data has been considered as an effective tool for reducing health care costs by eliminating adverse events and reducing readmissions to hospitals. The purposes of this study were to examine the emergence of big data in the US health care industry, to evaluate a hospital's ability to effectively use complex information, and to predict the potential benefits that hospitals might realize if they are successful in using big data. The findings of the research suggest that there were a number of benefits expected by hospitals when using big data analytics, including cost savings and business intelligence. By using big data, many hospitals have recognized that there have been challenges, including lack of experience and cost of developing the analytics. Many hospitals will need to invest in the acquiring of adequate personnel with experience in big data analytics and data integration. The findings of this study suggest that the adoption, implementation, and utilization of big data technology will have a profound positive effect among health care providers.

  6. Big Data Strategy for Telco: Network Transformation

    OpenAIRE

    F. Amin; S. Feizi

    2014-01-01

    Big data has the potential to improve the quality of services; enable infrastructure that businesses depend on to adapt continually and efficiently; improve the performance of employees; help organizations better understand customers; and reduce liability risks. Analytics and marketing models of fixed and mobile operators are falling short in combating churn and declining revenue per user. Big Data presents new method to reverse the way and improve profitability. The benefits of Big Data and ...

  7. Big Data in Shipping - Challenges and Opportunities

    OpenAIRE

    Rødseth, Ørnulf Jan; Perera, Lokukaluge Prasad; Mo, Brage

    2016-01-01

    Big Data is getting popular in shipping where large amounts of information is collected to better understand and improve logistics, emissions, energy consumption and maintenance. Constraints to the use of big data include cost and quality of on-board sensors and data acquisition systems, satellite communication, data ownership and technical obstacles to effective collection and use of big data. New protocol standards may simplify the process of collecting and organizing the data, including in...

  8. New insights into the role of Mn and Fe in coloring origin of blue decorations of blue-and-white porcelains by XANES spectroscopy

    International Nuclear Information System (INIS)

    Zhu, Jian; Luo, Wugan; Ming, Chaofang; Wang, Changsui; Chen, Dongliang; Xu, Wei; Wang, Lihua

    2013-01-01

    Blue and white porcelain is one of the most valuable ancient ceramics varieties in ancient China. It is well known for its beautiful blue decorations. However, the origin of its blue color has not been very clear till now. In this research, two blue and white porcelains from Jingdezhen, Jiangxi province were selected and Mn and Fe K-edge XANES spectra were recorded from blue decorations with or without transparent glaze. Results showed that Mn K-edge XANES features were almost identical between different samples while that of iron changed. The above findings indicated the positive role of iron in the variation of blue decorations. As for manganese, although more system researches were need, its negative role on the variations of the tone of blue decorations was obtained. On the other hand, the paper also revealed the XAFS results will be affect by the glaze layer above the pigment. These findings provided us more information to understand the coloring origin of blue decorations of blue-and-white porcelain by means of XANES spectroscopy.

  9. New insights into the role of Mn and Fe in coloring origin of blue decorations of blue-and-white porcelains by XANES spectroscopy

    Science.gov (United States)

    Zhu, Jian; Luo, Wugan; Chen, Dongliang; Xu, Wei; Ming, Chaofang; Wang, Changsui; Wang, Lihua

    2013-04-01

    Blue and white porcelain is one of the most valuable ancient ceramics varieties in ancient China. It is well known for its beautiful blue decorations. However, the origin of its blue color has not been very clear till now. In this research, two blue and white porcelains from Jingdezhen, Jiangxi province were selected and Mn and Fe K-edge XANES spectra were recorded from blue decorations with or without transparent glaze. Results showed that Mn K-edge XANES features were almost identical between different samples while that of iron changed. The above findings indicated the positive role of iron in the variation of blue decorations. As for manganese, although more system researches were need, its negative role on the variations of the tone of blue decorations was obtained. On the other hand, the paper also revealed the XAFS results will be affect by the glaze layer above the pigment. These findings provided us more information to understand the coloring origin of blue decorations of blue-and-white porcelain by means of XANES spectroscopy.

  10. [Relevance of big data for molecular diagnostics].

    Science.gov (United States)

    Bonin-Andresen, M; Smiljanovic, B; Stuhlmüller, B; Sörensen, T; Grützkau, A; Häupl, T

    2018-04-01

    Big data analysis raises the expectation that computerized algorithms may extract new knowledge from otherwise unmanageable vast data sets. What are the algorithms behind the big data discussion? In principle, high throughput technologies in molecular research already introduced big data and the development and application of analysis tools into the field of rheumatology some 15 years ago. This includes especially omics technologies, such as genomics, transcriptomics and cytomics. Some basic methods of data analysis are provided along with the technology, however, functional analysis and interpretation requires adaptation of existing or development of new software tools. For these steps, structuring and evaluating according to the biological context is extremely important and not only a mathematical problem. This aspect has to be considered much more for molecular big data than for those analyzed in health economy or epidemiology. Molecular data are structured in a first order determined by the applied technology and present quantitative characteristics that follow the principles of their biological nature. These biological dependencies have to be integrated into software solutions, which may require networks of molecular big data of the same or even different technologies in order to achieve cross-technology confirmation. More and more extensive recording of molecular processes also in individual patients are generating personal big data and require new strategies for management in order to develop data-driven individualized interpretation concepts. With this perspective in mind, translation of information derived from molecular big data will also require new specifications for education and professional competence.

  11. Nature's palette: the search for natural blue colorants.

    Science.gov (United States)

    Newsome, Andrew G; Culver, Catherine A; van Breemen, Richard B

    2014-07-16

    The food and beverage industry is seeking to broaden the palette of naturally derived colorants. Although considerable effort has been devoted to the search for new blue colorants in fruits and vegetables, less attention has been directed toward blue compounds from other sources such as bacteria and fungi. The current work reviews known organic blue compounds from natural plant, animal, fungal, and microbial sources. The scarcity of blue-colored metabolites in the natural world relative to metabolites of other colors is discussed, and structural trends common among natural blue compounds are identified. These compounds are grouped into seven structural classes and evaluated for their potential as new color additives.

  12. Big data in psychology: A framework for research advancement.

    Science.gov (United States)

    Adjerid, Idris; Kelley, Ken

    2018-02-22

    The potential for big data to provide value for psychology is significant. However, the pursuit of big data remains an uncertain and risky undertaking for the average psychological researcher. In this article, we address some of this uncertainty by discussing the potential impact of big data on the type of data available for psychological research, addressing the benefits and most significant challenges that emerge from these data, and organizing a variety of research opportunities for psychology. Our article yields two central insights. First, we highlight that big data research efforts are more readily accessible than many researchers realize, particularly with the emergence of open-source research tools, digital platforms, and instrumentation. Second, we argue that opportunities for big data research are diverse and differ both in their fit for varying research goals, as well as in the challenges they bring about. Ultimately, our outlook for researchers in psychology using and benefiting from big data is cautiously optimistic. Although not all big data efforts are suited for all researchers or all areas within psychology, big data research prospects are diverse, expanding, and promising for psychology and related disciplines. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  13. 'Big data' in pharmaceutical science: challenges and opportunities.

    Science.gov (United States)

    Dossetter, Al G; Ecker, Gerhard; Laverty, Hugh; Overington, John

    2014-05-01

    Future Medicinal Chemistry invited a selection of experts to express their views on the current impact of big data in drug discovery and design, as well as speculate on future developments in the field. The topics discussed include the challenges of implementing big data technologies, maintaining the quality and privacy of data sets, and how the industry will need to adapt to welcome the big data era. Their enlightening responses provide a snapshot of the many and varied contributions being made by big data to the advancement of pharmaceutical science.

  14. Soft computing in big data processing

    CERN Document Server

    Park, Seung-Jong; Lee, Jee-Hyong

    2014-01-01

    Big data is an essential key to build a smart world as a meaning of the streaming, continuous integration of large volume and high velocity data covering from all sources to final destinations. The big data range from data mining, data analysis and decision making, by drawing statistical rules and mathematical patterns through systematical or automatically reasoning. The big data helps serve our life better, clarify our future and deliver greater value. We can discover how to capture and analyze data. Readers will be guided to processing system integrity and implementing intelligent systems. With intelligent systems, we deal with the fundamental data management and visualization challenges in effective management of dynamic and large-scale data, and efficient processing of real-time and spatio-temporal data. Advanced intelligent systems have led to managing the data monitoring, data processing and decision-making in realistic and effective way. Considering a big size of data, variety of data and frequent chan...

  15. Phototherapy with blue and green mixed-light is as effective against unconjugated jaundice as blue light and reduces oxidative stress in the Gunn rat model.

    Science.gov (United States)

    Uchida, Yumiko; Morimoto, Yukihiro; Uchiike, Takao; Kamamoto, Tomoyuki; Hayashi, Tamaki; Arai, Ikuyo; Nishikubo, Toshiya; Takahashi, Yukihiro

    2015-07-01

    Phototherapy using blue light-emitting diodes (LED) is effective against neonatal jaundice. However, green light phototherapy also reduces unconjugated jaundice. We aimed to determine whether mixed blue and green light can relieve jaundice with minimal oxidative stress as effectively as either blue or green light alone in a rat model. Gunn rats were exposed to phototherapy with blue (420-520 nm), filtered blue (FB; 440-520 nm without 1.00), respectively. Blue plus green phototherapy is as effective as blue phototherapy and it attenuates irradiation-induced oxidative stress. Combined blue and green spectra might be effective against neonatal hyperbilirubinemia. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  16. Solution of a braneworld big crunch/big bang cosmology

    International Nuclear Information System (INIS)

    McFadden, Paul L.; Turok, Neil; Steinhardt, Paul J.

    2007-01-01

    We solve for the cosmological perturbations in a five-dimensional background consisting of two separating or colliding boundary branes, as an expansion in the collision speed V divided by the speed of light c. Our solution permits a detailed check of the validity of four-dimensional effective theory in the vicinity of the event corresponding to the big crunch/big bang singularity. We show that the four-dimensional description fails at the first nontrivial order in (V/c) 2 . At this order, there is nontrivial mixing of the two relevant four-dimensional perturbation modes (the growing and decaying modes) as the boundary branes move from the narrowly separated limit described by Kaluza-Klein theory to the well-separated limit where gravity is confined to the positive-tension brane. We comment on the cosmological significance of the result and compute other quantities of interest in five-dimensional cosmological scenarios

  17. [Big data and their perspectives in radiation therapy].

    Science.gov (United States)

    Guihard, Sébastien; Thariat, Juliette; Clavier, Jean-Baptiste

    2017-02-01

    The concept of big data indicates a change of scale in the use of data and data aggregation into large databases through improved computer technology. One of the current challenges in the creation of big data in the context of radiation therapy is the transformation of routine care items into dark data, i.e. data not yet collected, and the fusion of databases collecting different types of information (dose-volume histograms and toxicity data for example). Processes and infrastructures devoted to big data collection should not impact negatively on the doctor-patient relationship, the general process of care or the quality of the data collected. The use of big data requires a collective effort of physicians, physicists, software manufacturers and health authorities to create, organize and exploit big data in radiotherapy and, beyond, oncology. Big data involve a new culture to build an appropriate infrastructure legally and ethically. Processes and issues are discussed in this article. Copyright © 2016 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  18. Current applications of big data in obstetric anesthesiology.

    Science.gov (United States)

    Klumpner, Thomas T; Bauer, Melissa E; Kheterpal, Sachin

    2017-06-01

    The narrative review aims to highlight several recently published 'big data' studies pertinent to the field of obstetric anesthesiology. Big data has been used to study rare outcomes, to identify trends within the healthcare system, to identify variations in practice patterns, and to highlight potential inequalities in obstetric anesthesia care. Big data studies have helped define the risk of rare complications of obstetric anesthesia, such as the risk of neuraxial hematoma in thrombocytopenic parturients. Also, large national databases have been used to better understand trends in anesthesia-related adverse events during cesarean delivery as well as outline potential racial/ethnic disparities in obstetric anesthesia care. Finally, real-time analysis of patient data across a number of disparate health information systems through the use of sophisticated clinical decision support and surveillance systems is one promising application of big data technology on the labor and delivery unit. 'Big data' research has important implications for obstetric anesthesia care and warrants continued study. Real-time electronic surveillance is a potentially useful application of big data technology on the labor and delivery unit.

  19. Volume and Value of Big Healthcare Data.

    Science.gov (United States)

    Dinov, Ivo D

    Modern scientific inquiries require significant data-driven evidence and trans-disciplinary expertise to extract valuable information and gain actionable knowledge about natural processes. Effective evidence-based decisions require collection, processing and interpretation of vast amounts of complex data. The Moore's and Kryder's laws of exponential increase of computational power and information storage, respectively, dictate the need rapid trans-disciplinary advances, technological innovation and effective mechanisms for managing and interrogating Big Healthcare Data. In this article, we review important aspects of Big Data analytics and discuss important questions like: What are the challenges and opportunities associated with this biomedical, social, and healthcare data avalanche? Are there innovative statistical computing strategies to represent, model, analyze and interpret Big heterogeneous data? We present the foundation of a new compressive big data analytics (CBDA) framework for representation, modeling and inference of large, complex and heterogeneous datasets. Finally, we consider specific directions likely to impact the process of extracting information from Big healthcare data, translating that information to knowledge, and deriving appropriate actions.

  20. MOCK OBSERVATIONS OF BLUE STRAGGLERS IN GLOBULAR CLUSTER MODELS

    International Nuclear Information System (INIS)

    Sills, Alison; Glebbeek, Evert; Chatterjee, Sourav; Rasio, Frederic A.

    2013-01-01

    We created artificial color-magnitude diagrams of Monte Carlo dynamical models of globular clusters and then used observational methods to determine the number of blue stragglers in those clusters. We compared these blue stragglers to various cluster properties, mimicking work that has been done for blue stragglers in Milky Way globular clusters to determine the dominant formation mechanism(s) of this unusual stellar population. We find that a mass-based prescription for selecting blue stragglers will select approximately twice as many blue stragglers than a selection criterion that was developed for observations of real clusters. However, the two numbers of blue stragglers are well-correlated, so either selection criterion can be used to characterize the blue straggler population of a cluster. We confirm previous results that the simplified prescription for the evolution of a collision or merger product in the BSE code overestimates their lifetimes. We show that our model blue stragglers follow similar trends with cluster properties (core mass, binary fraction, total mass, collision rate) as the true Milky Way blue stragglers as long as we restrict ourselves to model clusters with an initial binary fraction higher than 5%. We also show that, in contrast to earlier work, the number of blue stragglers in the cluster core does have a weak dependence on the collisional parameter Γ in both our models and in Milky Way globular clusters

  1. Using Big Book to Teach Things in My House

    OpenAIRE

    Effrien, Intan; Lailatus, Sa’diyah; Nuruliftitah Maja, Neneng

    2017-01-01

    The purpose of this study to determine students' interest in learning using the big book media. Big book is a big book from the general book. The big book contains simple words and images that match the content of sentences and spelling. From here researchers can know the interest and development of students' knowledge. As well as train researchers to remain crative in developing learning media for students.

  2. Speed Bumps on the Road to Sustainability - Energy Technology and Geopolitics

    International Nuclear Information System (INIS)

    Mandil, C.; Taylor, P.; Van Der Linde, C.; Buchner, B.; Ramsay, W.C.; Lipponen, J.; Meier, A.; Berkeley, L.; Di Paola-Galloni, J.L.; Jaureguy-Naudin, M.; Charpin, J.M.; Segar, Ch.; Zaleski, P.; Lesourne, J.; Pires Santos, A.; Menard, D.; Neuhoff, K.; Oettinger, G.

    2011-01-01

    This document gathers the slides of the available presentations given at the 2011 issue of the annual Conference of the Ifri (French Institute of International Relations) Energy Program: 1 - An Energy revolution under way (Peter Taylor, Head of the Energy Technology Division, International Energy Agency); 2 - A look back at Cancun: 'top down' versus 'bottom up' (Barbara Buchner, Director of the CPI - Climate Policy Initiative - Venice office; 3 - CCS: Still in the Starting Blocks? (Juho Lipponen, Head of CCS Unit, International Energy Agency); 4 - Energy Efficiency: Does Anyone Care? (Alan Meier, Senior Scientist and Principal Investigator, Lawrence Berkeley National Laboratory); 5 - The Transport Sector: Anything Goes? (Jean-Luc di Paola-Galloni, Corporate Vice-President, Sustainable Development and External Affairs, Valeo Group); 6 - The Mediterranean Ring: Power or Politics? (Jean-Michel Charpin, Inspecteur General des Finances); 7 - Iran gas and Iraq oil (Chris Segar, Regional Analyst/Middle East and North Africa, International Energy Agency); 8 - Nuclear Power: New Players, New Game, New Rules (Pierre Zaleski, General delegate for the Center of Geopolitics of Energy and Raw Materials, Universite Paris-Dauphine); 9 - The Grid: a Generic Speed Bump (Antonio Pires Santos, Energy and Utilities Industry Leader, Southwest Europe, IBM); 10 - Intellectual Property Rights/Technology transfer (Dominique Menard, Partner, Hogan Lovells (Paris) LLP); 11 - Energy Markets: Conducive to Sustainability (Karsten Neuhoff, Director of the CPI - Climate Policy Initiative - Berlin office, German Institute for Economic Research, DIW Berlin)

  3. Speed Bumps on the Road to Sustainability - Energy Technology and Geopolitics

    Energy Technology Data Exchange (ETDEWEB)

    Mandil, C.; Taylor, P.; Van Der Linde, C.; Buchner, B.; Ramsay, W.C.; Lipponen, J.; Meier, A.; Berkeley, L.; Di Paola-Galloni, J.L.; Jaureguy-Naudin, M.; Charpin, J.M.; Segar, Ch.; Zaleski, P.; Lesourne, J.; Pires Santos, A.; Menard, D.; Neuhoff, K.; Oettinger, G.

    2011-07-01

    This document gathers the slides of the available presentations given at the 2011 issue of the annual Conference of the Ifri (French Institute of International Relations) Energy Program: 1 - An Energy revolution under way (Peter Taylor, Head of the Energy Technology Division, International Energy Agency); 2 - A look back at Cancun: 'top down' versus 'bottom up' (Barbara Buchner, Director of the CPI - Climate Policy Initiative - Venice office; 3 - CCS: Still in the Starting Blocks? (Juho Lipponen, Head of CCS Unit, International Energy Agency); 4 - Energy Efficiency: Does Anyone Care? (Alan Meier, Senior Scientist and Principal Investigator, Lawrence Berkeley National Laboratory); 5 - The Transport Sector: Anything Goes? (Jean-Luc di Paola-Galloni, Corporate Vice-President, Sustainable Development and External Affairs, Valeo Group); 6 - The Mediterranean Ring: Power or Politics? (Jean-Michel Charpin, Inspecteur General des Finances); 7 - Iran gas and Iraq oil (Chris Segar, Regional Analyst/Middle East and North Africa, International Energy Agency); 8 - Nuclear Power: New Players, New Game, New Rules (Pierre Zaleski, General delegate for the Center of Geopolitics of Energy and Raw Materials, Universite Paris-Dauphine); 9 - The Grid: a Generic Speed Bump (Antonio Pires Santos, Energy and Utilities Industry Leader, Southwest Europe, IBM); 10 - Intellectual Property Rights/Technology transfer (Dominique Menard, Partner, Hogan Lovells (Paris) LLP); 11 - Energy Markets: Conducive to Sustainability (Karsten Neuhoff, Director of the CPI - Climate Policy Initiative - Berlin office, German Institute for Economic Research, DIW Berlin)

  4. Big Data Analytics Methodology in the Financial Industry

    Science.gov (United States)

    Lawler, James; Joseph, Anthony

    2017-01-01

    Firms in industry continue to be attracted by the benefits of Big Data Analytics. The benefits of Big Data Analytics projects may not be as evident as frequently indicated in the literature. The authors of the study evaluate factors in a customized methodology that may increase the benefits of Big Data Analytics projects. Evaluating firms in the…

  5. Alcian blue-stained particles in a eutrophic lake

    DEFF Research Database (Denmark)

    Worm, J.; Søndergaard, Morten

    1998-01-01

    We used a neutral solution of Alcian Blue to stain transparent particles in eutrophic Lake Frederiksborg Slotss0, Denmark. Alcian Blue-stained particles (ABSP) appeared to be similar to the so-called transparent exopolymer particles (TEP) identified with an acidic solution of Alcian Blue. Our...

  6. FIXED-BED COLUMN ADSORPTION OF METHYL BLUE USING ...

    African Journals Online (AJOL)

    userpc

    Axle Wood Carbon (AWC) was used to study the removal of Methyl Blue (MB) from ... height, initial methyl blue (MB) concentration, .... colour from blue to dark purple- .... Environ. Earth Sci. 13; 1–13. Yagub, M. T., Sen, T. K., Afroze, S., and Ang,.

  7. Big data: survey, technologies, opportunities, and challenges.

    Science.gov (United States)

    Khan, Nawsher; Yaqoob, Ibrar; Hashem, Ibrahim Abaker Targio; Inayat, Zakira; Ali, Waleed Kamaleldin Mahmoud; Alam, Muhammad; Shiraz, Muhammad; Gani, Abdullah

    2014-01-01

    Big Data has gained much attention from the academia and the IT industry. In the digital and computing world, information is generated and collected at a rate that rapidly exceeds the boundary range. Currently, over 2 billion people worldwide are connected to the Internet, and over 5 billion individuals own mobile phones. By 2020, 50 billion devices are expected to be connected to the Internet. At this point, predicted data production will be 44 times greater than that in 2009. As information is transferred and shared at light speed on optic fiber and wireless networks, the volume of data and the speed of market growth increase. However, the fast growth rate of such large data generates numerous challenges, such as the rapid growth of data, transfer speed, diverse data, and security. Nonetheless, Big Data is still in its infancy stage, and the domain has not been reviewed in general. Hence, this study comprehensively surveys and classifies the various attributes of Big Data, including its nature, definitions, rapid growth rate, volume, management, analysis, and security. This study also proposes a data life cycle that uses the technologies and terminologies of Big Data. Future research directions in this field are determined based on opportunities and several open issues in Big Data domination. These research directions facilitate the exploration of the domain and the development of optimal techniques to address Big Data.

  8. Big Data: Survey, Technologies, Opportunities, and Challenges

    Science.gov (United States)

    Khan, Nawsher; Yaqoob, Ibrar; Hashem, Ibrahim Abaker Targio; Inayat, Zakira; Mahmoud Ali, Waleed Kamaleldin; Alam, Muhammad; Shiraz, Muhammad; Gani, Abdullah

    2014-01-01

    Big Data has gained much attention from the academia and the IT industry. In the digital and computing world, information is generated and collected at a rate that rapidly exceeds the boundary range. Currently, over 2 billion people worldwide are connected to the Internet, and over 5 billion individuals own mobile phones. By 2020, 50 billion devices are expected to be connected to the Internet. At this point, predicted data production will be 44 times greater than that in 2009. As information is transferred and shared at light speed on optic fiber and wireless networks, the volume of data and the speed of market growth increase. However, the fast growth rate of such large data generates numerous challenges, such as the rapid growth of data, transfer speed, diverse data, and security. Nonetheless, Big Data is still in its infancy stage, and the domain has not been reviewed in general. Hence, this study comprehensively surveys and classifies the various attributes of Big Data, including its nature, definitions, rapid growth rate, volume, management, analysis, and security. This study also proposes a data life cycle that uses the technologies and terminologies of Big Data. Future research directions in this field are determined based on opportunities and several open issues in Big Data domination. These research directions facilitate the exploration of the domain and the development of optimal techniques to address Big Data. PMID:25136682

  9. Opportunity and Challenges for Migrating Big Data Analytics in Cloud

    Science.gov (United States)

    Amitkumar Manekar, S.; Pradeepini, G., Dr.

    2017-08-01

    Big Data Analytics is a big word now days. As per demanding and more scalable process data generation capabilities, data acquisition and storage become a crucial issue. Cloud storage is a majorly usable platform; the technology will become crucial to executives handling data powered by analytics. Now a day’s trend towards “big data-as-a-service” is talked everywhere. On one hand, cloud-based big data analytics exactly tackle in progress issues of scale, speed, and cost. But researchers working to solve security and other real-time problem of big data migration on cloud based platform. This article specially focused on finding possible ways to migrate big data to cloud. Technology which support coherent data migration and possibility of doing big data analytics on cloud platform is demanding in natute for new era of growth. This article also gives information about available technology and techniques for migration of big data in cloud.

  10. Hot big bang or slow freeze?

    Science.gov (United States)

    Wetterich, C.

    2014-09-01

    We confront the big bang for the beginning of the universe with an equivalent picture of a slow freeze - a very cold and slowly evolving universe. In the freeze picture the masses of elementary particles increase and the gravitational constant decreases with cosmic time, while the Newtonian attraction remains unchanged. The freeze and big bang pictures both describe the same observations or physical reality. We present a simple ;crossover model; without a big bang singularity. In the infinite past space-time is flat. Our model is compatible with present observations, describing the generation of primordial density fluctuations during inflation as well as the present transition to a dark energy-dominated universe.

  11. Big Data

    DEFF Research Database (Denmark)

    Aaen, Jon; Nielsen, Jeppe Agger

    2016-01-01

    Big Data byder sig til som en af tidens mest hypede teknologiske innovationer, udråbt til at rumme kimen til nye, værdifulde operationelle indsigter for private virksomheder og offentlige organisationer. Mens de optimistiske udmeldinger er mange, er forskningen i Big Data i den offentlige sektor...... indtil videre begrænset. Denne artikel belyser, hvordan den offentlige sundhedssektor kan genanvende og udnytte en stadig større mængde data under hensyntagen til offentlige værdier. Artiklen bygger på et casestudie af anvendelsen af store mængder sundhedsdata i Dansk AlmenMedicinsk Database (DAMD......). Analysen viser, at (gen)brug af data i nye sammenhænge er en flerspektret afvejning mellem ikke alene økonomiske rationaler og kvalitetshensyn, men også kontrol over personfølsomme data og etiske implikationer for borgeren. I DAMD-casen benyttes data på den ene side ”i den gode sags tjeneste” til...

  12. Curating Big Data Made Simple: Perspectives from Scientific Communities.

    Science.gov (United States)

    Sowe, Sulayman K; Zettsu, Koji

    2014-03-01

    The digital universe is exponentially producing an unprecedented volume of data that has brought benefits as well as fundamental challenges for enterprises and scientific communities alike. This trend is inherently exciting for the development and deployment of cloud platforms to support scientific communities curating big data. The excitement stems from the fact that scientists can now access and extract value from the big data corpus, establish relationships between bits and pieces of information from many types of data, and collaborate with a diverse community of researchers from various domains. However, despite these perceived benefits, to date, little attention is focused on the people or communities who are both beneficiaries and, at the same time, producers of big data. The technical challenges posed by big data are as big as understanding the dynamics of communities working with big data, whether scientific or otherwise. Furthermore, the big data era also means that big data platforms for data-intensive research must be designed in such a way that research scientists can easily search and find data for their research, upload and download datasets for onsite/offsite use, perform computations and analysis, share their findings and research experience, and seamlessly collaborate with their colleagues. In this article, we present the architecture and design of a cloud platform that meets some of these requirements, and a big data curation model that describes how a community of earth and environmental scientists is using the platform to curate data. Motivation for developing the platform, lessons learnt in overcoming some challenges associated with supporting scientists to curate big data, and future research directions are also presented.

  13. Big data analytics in healthcare: promise and potential.

    Science.gov (United States)

    Raghupathi, Wullianallur; Raghupathi, Viju

    2014-01-01

    To describe the promise and potential of big data analytics in healthcare. The paper describes the nascent field of big data analytics in healthcare, discusses the benefits, outlines an architectural framework and methodology, describes examples reported in the literature, briefly discusses the challenges, and offers conclusions. The paper provides a broad overview of big data analytics for healthcare researchers and practitioners. Big data analytics in healthcare is evolving into a promising field for providing insight from very large data sets and improving outcomes while reducing costs. Its potential is great; however there remain challenges to overcome.

  14. Data warehousing in the age of big data

    CERN Document Server

    Krishnan, Krish

    2013-01-01

    Data Warehousing in the Age of the Big Data will help you and your organization make the most of unstructured data with your existing data warehouse. As Big Data continues to revolutionize how we use data, it doesn't have to create more confusion. Expert author Krish Krishnan helps you make sense of how Big Data fits into the world of data warehousing in clear and concise detail. The book is presented in three distinct parts. Part 1 discusses Big Data, its technologies and use cases from early adopters. Part 2 addresses data warehousing, its shortcomings, and new architecture

  15. Blue light-induced oxidative stress in live skin.

    Science.gov (United States)

    Nakashima, Yuya; Ohta, Shigeo; Wolf, Alexander M

    2017-07-01

    Skin damage from exposure to sunlight induces aging-like changes in appearance and is attributed to the ultraviolet (UV) component of light. Photosensitized production of reactive oxygen species (ROS) by UVA light is widely accepted to contribute to skin damage and carcinogenesis, but visible light is thought not to do so. Using mice expressing redox-sensitive GFP to detect ROS, blue light could produce oxidative stress in live skin. Blue light induced oxidative stress preferentially in mitochondria, but green, red, far red or infrared light did not. Blue light-induced oxidative stress was also detected in cultured human keratinocytes, but the per photon efficacy was only 25% of UVA in human keratinocyte mitochondria, compared to 68% of UVA in mouse skin. Skin autofluorescence was reduced by blue light, suggesting flavins are the photosensitizer. Exposing human skin to the blue light contained in sunlight depressed flavin autofluorescence, demonstrating that the visible component of sunlight has a physiologically significant effect on human skin. The ROS produced by blue light is probably superoxide, but not singlet oxygen. These results suggest that blue light contributes to skin aging similar to UVA. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. The Death of the Big Men

    DEFF Research Database (Denmark)

    Martin, Keir

    2010-01-01

    Recently Tolai people og Papua New Guinea have adopted the term 'Big Shot' to decribe an emerging post-colonial political elite. The mergence of the term is a negative moral evaluation of new social possibilities that have arisen as a consequence of the Big Shots' privileged position within a glo...

  17. Big data and software defined networks

    CERN Document Server

    Taheri, Javid

    2018-01-01

    Big Data Analytics and Software Defined Networking (SDN) are helping to drive the management of data usage of the extraordinary increase of computer processing power provided by Cloud Data Centres (CDCs). This new book investigates areas where Big-Data and SDN can help each other in delivering more efficient services.

  18. Compact and efficient blue laser sheet for measurement

    Science.gov (United States)

    Qi, Yan; Wang, Yu; Wu, Bin; Wang, Yanwei; Yan, Boxia

    2017-10-01

    Compact and efficient blue laser sheet has important applications in the field of measurement, with laser diode end pumped Nd:YAG directly and LBO intracavity frequency doubling, a compact and efficient CW 473nm blue laser sheet composed of dual path liner blue laser is realized. At an incident pump power of 12.4W, up to 1.4W output power of the compound blue laser is achieved, the optical-to-optical conversion efficiency is as high as 11.3%.

  19. Big Data-Survey

    Directory of Open Access Journals (Sweden)

    P.S.G. Aruna Sri

    2016-03-01

    Full Text Available Big data is the term for any gathering of information sets, so expensive and complex, that it gets to be hard to process for utilizing customary information handling applications. The difficulties incorporate investigation, catch, duration, inquiry, sharing, stockpiling, Exchange, perception, and protection infringement. To reduce spot business patterns, anticipate diseases, conflict etc., we require bigger data sets when compared with the smaller data sets. Enormous information is hard to work with utilizing most social database administration frameworks and desktop measurements and perception bundles, needing rather enormously parallel programming running on tens, hundreds, or even a large number of servers. In this paper there was an observation on Hadoop architecture, different tools used for big data and its security issues.

  20. Big Data Analytics, Infectious Diseases and Associated Ethical Impacts

    OpenAIRE

    Garattini, C.; Raffle, J.; Aisyah, D. N.; Sartain, F.; Kozlakidis, Z.

    2017-01-01

    The exponential accumulation, processing and accrual of big data in healthcare are only possible through an equally rapidly evolving field of big data analytics. The latter offers the capacity to rationalize, understand and use big data to serve many different purposes, from improved services modelling to prediction of treatment outcomes, to greater patient and disease stratification. In the area of infectious diseases, the application of big data analytics has introduced a number of changes ...