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Sample records for bien chiu han

  1. Privatizing Water in the Chilean Andes: The Case of Las Vegas de Chiu-Chiu

    Directory of Open Access Journals (Sweden)

    Manuel Prieto

    2015-08-01

    Full Text Available The Chilean water model has been described as a textbook example of a free-market water system. This article contributes to the critiques of this model by showing the effect of its implementation in the Atacameño community of Chiu-Chiu, located in the Atacama Desert in the south-central Andes. In this community, the privatization of water rights ignored local water management practices that had produced a high-altitude wetland (known as a vega. This led to the inhabitants’ dispossession of crucial water rights and to wetland degradation. This process belies statements that the Chilean model relies on an unregulated market and instead highlights the state’s role in marginalizing local irrigation practices by reducing the water consumption of the indigenous population while keeping the copper mining industry (the main source of Chilean income and related growing urban populations supplied with water.

  2. A covariant representation of the Ball-Chiu vertex

    CERN Document Server

    Ahmadiniaz, Naser

    2012-01-01

    In nonabelian gauge theory the three-gluon vertex function contains important structural information, in particular on infrared divergences, and is also an essential ingredient in the Schwinger-Dyson equations. Much effort has gone into analyzing its general structure, and at the one-loop level also a number of explicit computations have been done, using various approaches. Here we use the string-inspired formalism to unify the calculations of the scalar, spinor and gluon loop contributions to the one-loop vertex, leading to an extremely compact representation in all cases. The vertex is computed fully off-shell and in dimensionally continued form, so that it can be used as a building block for higher-loop calculations. We find that the Bern-Kosower loop replacement rules, originally derived for the on-shell case, hold off-shell as well. We explain the relation of the structure of this representation to the low-energy effective action, and establish the precise connection with the standard Ball-Chiu decomposi...

  3. A covariant representation of the Ball–Chiu vertex

    International Nuclear Information System (INIS)

    In nonabelian gauge theory the three-gluon vertex function contains important structural information, in particular on infrared divergences, and is also an essential ingredient in the Schwinger–Dyson equations. Much effort has gone into analyzing its general structure, and at the one-loop level also a number of explicit computations have been done, using various approaches. Here we use the string-inspired formalism to unify the calculations of the scalar, spinor and gluon loop contributions to the one-loop vertex, leading to an extremely compact representation in all cases. The vertex is computed fully off-shell and in dimensionally continued form, so that it can be used as a building block for higher-loop calculations. We find that the Bern–Kosower loop replacement rules, originally derived for the on-shell case, hold off-shell as well. We explain the relation of the structure of this representation to the low-energy effective action, and establish the precise connection with the standard Ball–Chiu decomposition of the vertex. This allows us also to predict that the vanishing of the completely antisymmetric coefficient function S of this decomposition is not a one-loop accident, but persists at higher-loop orders. The sum rule found by Binger and Brodsky, which leads to the vanishing of the one-loop vertex in N=4 SYM theory, in the present approach relates to worldline supersymmetry

  4. Cómo nadar bien

    OpenAIRE

    Navarro Valdivielso, Fernando; Díaz Ureña, Germán; González Vegas, Manuel J.

    2012-01-01

    Nadar bien o mejor es la pretensión final de este libro. Al proceso que se propone para este objetivo lo hemos denominado método NB (Nadar bien). Nuestro interés se centra en que todos los interesados y practicantes en la natación puedan perfeccionar su técnica y disfrutar del dominio de la técnica.

  5. El arte de vivir bien y dignamente

    Directory of Open Access Journals (Sweden)

    Aguinaga Benítez Oscar William

    1997-11-01

    Full Text Available

    Por tradición y a diferencia de otras culturas, nos han enseñado en la casa, escuela o colegio y mucho más en el trabajo a buscar amor, prosperidad, salud, felicidad y satisfacción en el exterior y jamás se nos ha hecho ver, ni se nos ha inculcado que la mayor riqueza está en el interior de cada uno de nosotros. Bien dice el doctor Dyer "se nos ha condicionado para creer que recibimos la gracia de la vida" y no para que disfrutemos de la inmortalidad de nuestro yo espiritual, se niega la opción de estar siempre acompañado de una energía que para muchos es lo divino y para otros es la conciencia.

  6. Evaluation on the Efficiency of Subsurface Drainage in Chiu-Fen Landslide at Northern Taiwan

    Science.gov (United States)

    Ying, L. Y.; Lin, D. G.

    2015-12-01

    For administrative district, the Chiu-Fen landslide is situated at northern Taiwan and comes within the jurisdiction of Ruei-Fang district, New Taipei City Government. Chiu-Fen village is a famous spot for sightseeing and tourism in Southeast Asia. In the last decade, for economic purpose, a vast area of slope land in Chiu-Fen area was reclaimed into business and commercial districts. However, due to the complicated geological and hydrological conditions, improper reclamation, and lack of appropriate soil and water conservation facilities, large scale landslides are frequently triggered by typhoon rainfall and causes damages to the transportation and residential building in the community. As a consequence, the government initiated a comprehensive field investigations and remediation plans to stabilize the landslide from 1997 and the remediation works were concentrated on subsurface drainages, namely the application of drainage well (a vertical shaft with multi-level horizontal drainage boreholes). To investigate the efficiency of drainage wells on the landslide, the A1-profile in the landslide which covers the drainage wells W2 and W4 was selected for a series of rainfall seepage and slope stability analyses. In addition, a 48-hrs design rainfall with return period of 25, 50 and 100 years based on the local meteorological data bank was adopted for the analyses. The numerical results indicate the factor safety FS of the three potential sliding surfaces within A1-profile are constantly keeping greater than one (FS > 1.0) and without decreasing with the elapsed time during rainfall. This implies that the subsurface drainage works can drain off the infiltrated rainwater from a high intensity and long duration rainfall and preserve the slope stability of landslides from deterioration. Finally, the efficiency of the drainage wells can be evaluated quantitatively in terms of the time-dependent factor of safety and the pore water pressure distribution on several potential

  7. Les controverses du bien mourir

    OpenAIRE

    Clapasson, Dominique; Pott, Murielle

    2009-01-01

    Actuellement, la question des situations de fin de vie se pose en problème social. La dénonciation du tabou de la mort et de l’acharnement thérapeutique suscite des interrogations éthiques relatives à la souffrance des malades. Dès lors, le bien mourir devient une préoccupation qui touche chacun d’entre-nous. En Suisse, l’aspiration à une mort pacifiée se meut en deux modèles distincts de la gestion des situations de fin de vie : les soins palliatifs et l’assistance au suicide. En oppositi...

  8. Bienes comunes, nuevos cercamientos y economía política popular

    OpenAIRE

    Lain Escandell, Bru

    2015-01-01

    Este artículo discute la creciente importancia que están adoptando los llamados bienes comunes en el ámbito de la creación cultural. Para ello se discuten críticamente dos importantes analogías que han emergido en los últimos años: la primera, entre los bienes comunes naturales y los digitales y la segunda, entre los viejos y los nuevos cercamientos digitales. El artículo demuestra que, si bien es cierto que ambas comparaciones deben abordarse con cautela, las similitudes entre ambas son nota...

  9. Hans Meyer

    Czech Academy of Sciences Publication Activity Database

    Jindra, Jiří

    Červený Kostelec : Pavel Mervart, 2013 - (Šimůnek, M.; Kostlán, A.), s. 149-153 ISBN 978-80-7465-041-3. - (Studies in the History of Sciences and Humanities. 29) Institutional support: RVO:68378114 Keywords : Hans Meyer * history of science * scholars Subject RIV: AB - History

  10. Productos derivados sobre bienes de consumo

    OpenAIRE

    Francisco Venegas Martinez; Salvador Cruz Ake

    2010-01-01

    Este trabajo de investigacion desarrolla un modelo de equilibrio general con expectativas racionales en tiempo continuo util para la determinacion de precios de contratos forward, contratos futuros, bonos cupon cero y opciones europeas (de compra y venta) sobre bienes de consumo. Para ello, el modelo considera un individuo representativo en una economia con dos bienes, los cuales son producidos con tecnologias estocasticas. Por ultimo, el modelo propuesto permite examinar estrategias para obt...

  11. Productos derivados sobre bienes de consumo

    OpenAIRE

    Francisco Venegas Martínez; Salvador Cruz Ake

    2010-01-01

    Este trabajo de investigación desarrolla un modelo de equilibrio general con expectativas racionales en tiempo continuo útil para la determinación de precios de contratos forward , contratos futuros, bonos cupón cero y opciones europeas (de compra y venta) sobre bienes de consumo. Para ello, el modelo considera un individuo representativo en una economía con dos bienes, los cuales son producidos con tecnologías estocásticas. Por último, el modelo propuesto permite examinar estrategias para o...

  12. La protección transfronteriza de los bienes inmateriales en el comercio internacional

    OpenAIRE

    De Miguel Asensio, Pedro Alberto

    2008-01-01

    RESUMEN Pese a los logros de los convenios internacionales en materia de propiedad industrial e intelectual, no se ha superado el modelo basado en la territorialidad. La creciente complejidad de las actividades de explotación e infracción de los bienes inmateriales y su alcance típicamente internacional han contribuido a acentuar el debate sobre la revisión de su tratamiento en los sistemas de Derecho internacional privado, al tiempo que han dado lugar a un interés por desarrollar estánda...

  13. Comment on ''A strategy of estimating fuel concentration in a direct liquid-feed fuel cell system'' [Y.J. Chiu, H.C. Lien, Journal of Power Sources 159 (2006) 1162-1168

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Rongrong; Xie, Xiaofeng; Li, Chunwen [Department of Automation, Tsinghua University, Beijing 100084 (China); Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084 (China)

    2008-12-01

    The strategy for estimating the methanol concentration provided by Chiu and Lien [Y.J. Chiu, H.C. Lien, Journal of Power Sources 159 (2006) 1162-1168] overlooks the performance degradation (PD) of a direct methanol fuel cell (DMFC). In addition, the method may not be suitable in practice. (author)

  14. Review - Critical Han Studies

    Directory of Open Access Journals (Sweden)

    Zhiguo Ye

    2013-12-01

    Full Text Available Review of: Thomas Mullaney, James Leibold, Stéphane Gros, and Eric Armand Vanden Bussche (eds. 2012. Critical Han Studies: The History, Representation, and Identity of China's Majority. Berkeley, Calif: University of California Press. This path-breaking volume is an academic collaboration that emerged out of the "Critical Han Studies Conference and Workshop" at Stanford University in April 2008. Eleven scholars contributed to the question of what it means to be 'Han' in China, both historically and at present. Constituting over ninety percent of China's population, the Han are not only the largest ethnic group in China, but are also one of the largest categories of collective identity in the world. Despite this, the dominant Han group has so far eluded careful scholarly scrutiny, with the Han often referred to as an unmarked majority category in contemporary China. This volume challenges such conventional views by conceptualizing new interdisciplinary approaches to the question of Hanness. The eleven essays of the volume are divided into three themes: 'Han and China', 'The Problem of Han Origins', and 'The Problem of Han Formations'. The first theme, comprised of four essays, analyzes the ties that bind the category of Han to those of Chinese ethnicity, race, and polity. Kevin Carrico in "Recentering China: The Cantonese in and Beyond the Han" questions a single, unitary Hanness that he believes conceals "countless other perceived and imagined lines of differentiation" (25. The study examines how multiple identities...

  15. Bien y principio en Platón. Bien et principe chez Platon

    OpenAIRE

    Ramón Cámara, Begoña

    2015-01-01

    La tesis doctoral Bien y principio en Platón (Universitat de València y Université Paris Ouest Nanterre La Défense), escrita por Begoña Ramón y dirigida por los Profesores Tomás Calvo y Francis Wolff, viene a cubrir una laguna en los estudios sobre la Idea del Bien en Platón. Y es que, aunque se ha escrito mucho sobre el Bien en Platón, esta cuestión de permanente interés no ha sido nunca estudiada de manera acertada y suficiente. El presente trabajo trata de aportar por primera vez una defin...

  16. Prospective du commerce physique de biens culturels

    OpenAIRE

    Moati, Philippe

    2015-01-01

    Le commerce physique de biens culturels se trouve pris sous les feux croisés de deux tendances lourdes. La révolution numérique a d’abord fait naître un nouveau circuit de distribution – le commerce électronique –, lequel a immédiatement trouvé dans le domaine culturel l’un de ses terrains de développement les plus actifs. Elle a ensuite rendu possible la dématérialisation des contenus culturels : des fichiers informatiques, délivrés de machine à machine, deviennent des concurrents directs de...

  17. Prospective du commerce physique de biens culturels

    OpenAIRE

    Moati, Philippe; Chantepie, Philippe

    2015-01-01

    Si le commerce physique des biens culturels reste le maillon économique central de l’économie de la création, quel est son avenir dans le contexte de la révolution numérique qui tend à déstructurer les filières par le double effet de la dématérialisation des contenus culturels et de la migration d’une partie de l’offre et des transactions dans l’univers numérique ? L’exercice prospectif à court terme (horizon 2015) tente, à partir de l’identification des tendances lourdes et de l’observation ...

  18. Sobre el desarrollo de la teoría de los bienes públicos locales

    Directory of Open Access Journals (Sweden)

    Miltón Samuel Camelo

    2015-12-01

    Full Text Available La teoría de los bienes públicos locales toma forma desde la concepciónde la hipótesis de Tiebout, que es el primer planteamiento que tuvo en cuentala dimensión espacial de los bienes públicos, y constituye un mecanismo para la revelación de las preferencias sobre este tipo de bienes. Este trabajo desarrolla la analogía entre el modelo de Tiebout y el modelo neoclásico como una herramienta de dirección del trabajo y no como fin mismo pues, de lo contrario, puede terminar en una discusión ideológica que no es pertinente. Se examina el desarrollo de la teoría a través de la revisión de tópicos relevantes y aportes que han enriquecido y complementado el modelo de Tiebout; y, finalmente, describe elementos esenciales que debe incorporar la teoría para que tenga un mayor poder explicativo.

  19. Biene und Honig im pharaonischen Ägypten

    OpenAIRE

    Feierabend, Birgit Sonja

    2009-01-01

    Ziel der Dissertation war es, eine Gesamtbetrachtung der altägyptischen Bienenhaltung zu geben, die Bedeutung der Biene herauszuarbeiten und den Gebrauch des Honigs im alten Ägypten vorzustellen. Darüber hinaus wurde die Herkunft und Zusammensetzung des Honigs untersucht sowie ein Vergleich mit der Bienenhaltung in den Nachbarländern gezogen. rnrnDie Biene ist mehrfach als Symbol oder Dekorationselement vorzufinden. Bereits am Ende des Alten Reiches, einem Zeitpunkt, als sich die Domestikatio...

  20. Special issue: Hans Bethe

    CERN Multimedia

    Gottfried, Kurt

    2005-01-01

    "There are a handful of people who soar, whose accompalishments are so off-scale as to nearly defy belief. Hans Bethe (2 July 1906 - 6 March 2005) was of that caliber. As just one measure of his stature, imagine the task of copying his published opus by hand, for that is how he wrote most of it" (2 pages)

  1. Hans Christian Andersen

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen

    2007-01-01

    The Danish author, Hans Christian Andersen, living in the 1800s expressed through his fairy tales and other stories an enthusiasm for the technological breakthroughs in that century with trains, etc. But he also showed great concern for what the natural science did to people by narrowing their mind...

  2. La Obra Bien Hecha para la mejora docente: un enfoque práctico en el Módulo Repoblaciones Forestales y Tratamientos Selvícolas

    OpenAIRE

    Ramírez-Valiente, María

    2015-01-01

    La ejecución de las diferentes actividades y prácticas que se realizan en los Ciclos Formativos han de contribuir a la cualificación profesional del alumnado que los cursa. Se entiende que sería mucho más efectiva desde la Obra Bien Hecha y la personalización educativa de dichos Ciclos. A partir de lo cual, el objetivo general del TFM es abordar de forma teórica-práctica la Obra Bien Hecha en el Módulo de Repoblaciones Forestales y Tratamientos Selvícolas (RFTS ) del Ciclo Formativo de Grado ...

  3. Hans Bethe's early life

    Science.gov (United States)

    Bernstein, Jeremy

    2012-10-01

    In 1937, two years after he moved to the US to escape Nazi persecution, the physicist Hans Bethe sent a letter to his mother in Germany. In it, he wrote, "I think I am about the leading theoretician in America. [Eugene] Wigner is certainly better and [Robert] Oppenheimer and [Edward] Teller probably just as good. But I do more and talk more and that counts too."

  4. Tribute to Hans Sann

    CERN Multimedia

    2003-01-01

    1945-2003 Hans Sann, an internationally recognized scientist, beloved colleague and friend, died in a tragic car accident, on May 27th, on one of his many travels to CERN. Employed at GSI, in Darmstadt, since 1979, Hans Sann devoted most of his scientific career to the development of large size gas detectors for nuclear and high-energy physics experiments at GSI, CERN and Berkeley. One of his main achievements, among many others, was the famous MUSIC detector, on which several projects at GSI, Berkeley and other research Institutes were based. The innovative results obtained in the study of the fluid-gas transition in nuclear matter would not have been possible without his contribution and the application of the MUSIC detector. A member of the ALICE Collaboration since 1996, Hans was leading two main ALICE sub-programmes, the development of the gas system and the cooling system for the TPC detector. In addition, he was involved in the development of a new technological concept for the resistor chain of the ...

  5. De la naturaleza del bien: contra los maniqueos

    OpenAIRE

    Agustin, Aurelio,, Santo, Obispo de Hipona

    2012-01-01

    El sumo bien, al cual no hay nada superior, es Dios; y por esto es un bien inmutable, realmente eterno e inmortal. Todos los otros bienes no son sino por él ; pero no de él. En efecto, lo que es de él, es lo que él mismo es; pero las cosas hechas por él, no son lo que es él mismo. Y por esto, si solo el es inmutable, todas las cosas que hizo, ya que las hizo de la nada, son mudables. En efecto, tan omnipotente es, que puede aún de la nada, es decir, de lo que absolutamente no es, hacer cosas ...

  6. Propriété, biens publics mondiaux, bien(s commun(s : Une lecture des concepts économiques

    Directory of Open Access Journals (Sweden)

    Jérôme Ballet

    2008-03-01

    Full Text Available La notion de bien public mondial s’est développée ces dernières années. Elle renvoie à un dépassement ambigu de la notion usuelle dans la théorie économique de bien public. A cette occasion elle ouvre le débat sur l’équité en complément de l’efficience. De ce fait, la confrontation de cette nouvelle notion avec l’analyse de l’efficience des régimes de propriété s’impose. Par ailleurs, la confrontation avec la notion de bien commun, notion elle aussi en développement, éclaire l’enjeu autour de l’équité.Property, Global Public Goods, Common Good(s : A Lecture. The concept of global public good emerged these last years. It proposes, in an ambiguous way, to go beyond the usual concept of public good. Then, added to usual questions on efficiency, the debate on fairness becomes a stake. Confrontation with analysis on property rights command attention, Furthermore, confrontation with the concept of common good, also a developing concept, highlight stake around fairness.

  7. The Hans Tausen drill

    DEFF Research Database (Denmark)

    Johnsen, Sigfus Johann; Dahl-Jensen, Dorthe; Steffensen, Jørgen Peder;

    2007-01-01

    In the mid-1990s, excellent results from the GRIP and GISP2 deep drilling projects in Greenland opened up funding for continued ice-coring efforts in Antarctica (EPICA) and Greenland (NorthGRIP). The Glaciology Group of the Niels Bohr Institute, University of Copenhagen, was assigned the task of...... providing drilling capability for these projects, as it had done for the GRIP project. The group decided to further simplify existing deep drill designs for better reliability and ease of handling. The drill design decided upon was successfully tested on Hans Tausen Ice Cap, Peary Land, Greenland, in 1995...

  8. Singer Han Hong

    Institute of Scientific and Technical Information of China (English)

    KIRIN; KID

    2000-01-01

    HAN Hong had a happy childhood in the beautiful Xigaze City, Tibet. From the children's chorus, the military art troupe, the Prize Winning Competition on TV, up to the institute of art, she has never stopped singing. The difference to other singers her age is that she not only wishes to be a singer but a composer. Not satisfied with just singing the songs of others, she began expressing her happiness and sadness by writing her own. Finally she finished her first collection Rays in Tibet, which is the fi...

  9. Economía del bien común y los DESC en la enseñanza del derecho constitucional

    OpenAIRE

    Garay Montañez, Nilda

    2013-01-01

    El presente es un trabajo que resulta de la aplicación de los principios básicos de la Economía del Bien Común en las clases de derecho constitucional. Principios que tienen estrecha relación con los denominados DESC: Derechos Económicos Sociales y Culturales que han venido desarrollándose en las sociedades donde el nivel de la pobreza es alto, es decir, los Estados de la región denominada de la periferia. Los Estados constitucionales occidentales han construido amplia doctrina al respecto, p...

  10. Interview Hans Blix

    CERN Multimedia

    2013-01-01

    The Thorium Energy Conference, ThEC13, ran from 27 to 31 October at CERN, addressing the scientific and technical advances offered by thorium – a silvery white metal four times more abundant than uranium in the Earth's crust – in alternative nuclear technologies for energy production and for the destruction of nuclear waste. Conference Chair Egil Lillestol invited Swedish diplomat and politician Hans Blix to talk about "Thorium Nuclear Power and Non-Proliferation". In a career spanning more than 50 years, Blix has been head of the International Atomic Energy Agency and the United Nations Monitoring, Verification and Inspection Commission. During the 1990s, CERN has been pioneering thorium technologies research with experiments instigated by Nobel laureate Carlo Rubbia, testing the basic concepts of a thorium-fuelled reactor driven by a proton accelerator.

  11. Bien común y ética pública: Alcances y límites del concepto tradicional de bien común

    OpenAIRE

    Dorando J. Michelini

    2007-01-01

    Con el concepto de bien común se ha hecho referencia, a través de la historia, a aquellos bienes materiales e inmateriales que no se circunscriben a una persona sino que remiten a todos y cada uno de los miembros de la sociedad. Entre esos bienes suelen contarse elementos básicos para la supervivencia humana biológica, como el aire y el agua, pero también el derecho a participar en el usufructo de los bienes de la cultura. En algunos casos, el bien común es equiparado al bienestar general; en...

  12. Hans Jürman 85 : Hans Jürman: kes ma olen? / Hans Jürman

    Index Scriptorium Estoniae

    Jürman, Hans, 1923-2014

    2010-01-01

    Hans Jürmani lapsepõlvest, kooliaastatest ning ülikooliajast. Olles hariduselt eesti filoloog on Hans Jürman töötanud ka apteekrina ja õpetajana, kuid suurema osa oma elust raamatukogudes, põhiliselt Tallinna Keskraamatukogus ja Eesti NSV Riiklikus Avalikus Raamatukogus, viimasel ajal tegeleb terminoloogiaga

  13. Reconsiderando las tecnologías sociales como bienes comunes

    Directory of Open Access Journals (Sweden)

    Ariel Vercelli

    2010-05-01

    Full Text Available En este artículo se describen las relaciones que se plantean entre las regulaciones sobre bienes materiales e intelectuales y las “tecnologías sociales”. Para ello, se utilizan algunas herramientas teórico-metodológicas provenientes del análisis socio-técnico y se aprovechan desarrollos conceptuales referidos a la caracterización de los “bienes comunes”. El artículo es parte de un ejercicio teórico donde las tecnologías sociales se consideran como bienes comunes. Con ello se busca problematizar el carácter jurídico-político que pueden adquirir algunas tecnologías sociales y, a su vez, analizar posibles formas de privatización y apropiación que éstas podrían sufrir por parte de corporaciones comerciales y Estados. In this article, the author describes relations proposed between the regulation of material and intellectual goods and the “social technologies.” To that end, theoretical-methodological tools from social-technical analysis are used, and conceptual developments related to the characterization of “common goods” are applied. The article is part of a theoretical exercise in which social technologies are taken to be common goods. For that purpose, the legal-political character that some social technologies may acquire is problematized, and, at the same time possible forms of privatization and appropriation that these might undergo by private business or the state are analyzed.

  14. Bien común, derecho social y ciencias sociales

    OpenAIRE

    Zamagni, Stefano

    2014-01-01

    Stefano Zamagni, Catedrático de Economía Política de la Universidad de Bolonia. Bien común, Derecho Social y Ciencias Sociales. Conferencia en la Universidad de Málaga el 4 de noviembre de 2014. Facultad de Derecho. Departamento de Derecho del Trabajo y de la Seguridad Social. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. Stefano Zamagni, profesor de Economía Política en la Universidad de Bolonia y en la John Hopkins University, es uno de los princi...

  15. El mercado de bienes ilegales: el caso de la droga

    Directory of Open Access Journals (Sweden)

    Becker , Gary S.

    2006-12-01

    Full Text Available Este artículo examina los costos de reducir el consumo de un bien declarando ilegal su producción y castigando a los productores ilegales. Las drogas son el ejemplo más destacado. Cuanto más inelástica es la demanda o la oferta, mayor es el incremento del costo social de reducir la producción con mayor represión. Así, el gasto público óptimo de capturar y condenar a los proveedores ilegales no sólo depende de la diferencia entre los valores social y privado del consumo sino también de las elasticidades. Cuando la demanda y la oferta no son muy elásticas, no paga hacer cumplir la prohibición a menos que el valor social sea negativo. También muestra que un impuesto monetario reduce la producción e incrementa el precio más que la represión óptima del bien si fuera ilegal, aunque algunos productores vayan a la clandestinidad para evadir el impuesto monetario. Los impuestos al consumo y las restricciones a las cantidades no son equivalentes cuando la represión tiene costos

  16. Le commerce électronique de biens culturels : contributions empiriques

    OpenAIRE

    Eang, Bora

    2012-01-01

    Cette thèse se présente sous la forme d’un volume de 134 pages composé de 5 articles de recherche. La thèse est une contribution empirique à la littérature qui s’est développée depuis le début des années 2000 sur les bouleversements introduits par Internet sur le commerce des biens culturels. Elle examine plus particulièrement un ensemble de questions portant sur la complémentarité ou la substitution des canaux de distribution, physiques et virtuels, l’effet de « Longue Traîne » et la dispers...

  17. Los bienes comunes intangibles en el capitalismo cognitivo.

    Directory of Open Access Journals (Sweden)

    Álvaro Ramis Olivos

    2014-10-01

    Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 Este texto analizará críticamente la actual fase económica para mostrar la importancia de los bienes comunes intangibles. Sondea la tesis de un nuevo modo de producción «en ciernes», basado en la gestión colaborativa. Analiza los intangibles de acuerdo a su calidad y carácter. Compara los sistemas de patentes y derechos de propiedad intelectual que permiten su apropiación y las resistencias a su «comoditización» desde el software libre y las propuestas de flexibilización de derechos de autor. Advierte sobre el «fetichismo tecnológico» y propone un marco mínimo de discernimiento en dilemas vinculados a estas materias. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}

  18. Ciberciudadanía, cultura y bienes públicos

    Directory of Open Access Journals (Sweden)

    Álvarez, J. Francisco

    2009-06-01

    Full Text Available Net society is provoking dramatic changes in several aspects of our daily life as cultural traits, business and the more disparages spheres of privacy and social life. We must attend both to freedom of access and to new services generation because of the peculiar form public goods are raising in the Net. To supersede individual capability limitations and to diffuse digital and cultural gaps, electronic government could be a cultural decisive tool in this phase of cibersociety enhancement. Technologies enhanced the human capabilities, as well as with the social actions and its framework, including cultural production and management. Technologies are also transforming the generation, reproduction and transmission of (social knowledge.La sociedad red transforma la vida cotidiana, las diversas manifestaciones culturales, los negocios, las esferas más diversas de la vida privada y social. La forma en que se generan los bienes públicos en la red exige una preocupación explícita por la libertad de acceso y la generación de nuevos servicios, que ayuden a superar limitaciones de los individuos y faciliten desdibujar las diversas brechas digitales y ciberculturales. El gobierno electrónico resulta culturalmente decisivo en esta fase de expansión de la cibersociedad. Las tecnologías amplían las capacidades humanas, expanden el espacio y las formas de acción social, incluidas la producción y gestión cultural. También producen cambios en las formas de generación, reproducción y transmisión del conocimiento (social.

  19. Economía institucional de un bien mayor

    Directory of Open Access Journals (Sweden)

    Óscar A. Alfonso Roa

    2007-12-01

    Full Text Available La provisión de los servicios de acueducto y alcantarillado en Colombia ha sido sometida, desde 1994, a una terapia consistente en la promoción de un modelo empresarial que se abre paso a costa de la estigmatización del municipio como mal prestador y como asignador ineficiente de unos recursos escasos. a quince años de operación del modelo empresarial y en desarrollo del Acto Legislativo 04 de 2007, el Gobierno nacional ha introducido otra reforma, en esta oportunidad al Sistema General de Participaciones, esgrimiendo en la exposición de motivos los mismos argumentos de antaño, cuando en verdad mediante la prestación directa de los municipios sólo se provee de estos servicios a una porción minoritaria de la población urbana del país. En la primera parte se discute la noción del agua potable como bien mayor y en la segunda se presenta una breve síntesis de la evolución institucional de la provisión del agua potable en colombia. en la tercera parte se discuten algunos rasgos centrales del proceso de urbanización de la población colombiana a la que se sirve con el servicio de acueducto mientras que en la última se analiza la coyuntura reciente con énfasis en la crítica a la reforma introducida por el acto Legislativo 04 de 2007. este artículo propone otros puntos de vista para criticar, además de la reforma en curso, las fallas de un esquema de provisión cifrado en un enfoque empresarial sometido a una inocua regulación, que no logra conciliar los intereses de ampliación de las ganancias de las empresas de servicios públicos con las aspiraciones sociales en materia de universalización y calidad de los servicios de acueducto y alcantarillado.

  20. Bien común y ética pública: Alcances y límites del concepto tradicional de bien común

    Directory of Open Access Journals (Sweden)

    Dorando J. Michelini

    2007-12-01

    Full Text Available Con el concepto de bien común se ha hecho referencia, a través de la historia, a aquellos bienes materiales e inmateriales que no se circunscriben a una persona sino que remiten a todos y cada uno de los miembros de la sociedad. Entre esos bienes suelen contarse elementos básicos para la supervivencia humana biológica, como el aire y el agua, pero también el derecho a participar en el usufructo de los bienes de la cultura. En algunos casos, el bien común es equiparado al bienestar general; en otros, a la suma de intereses particulares o al beneficio de la mayoría, como cuando se busca el mayor bien para el mayor número posible de individuos. Más allá de las diversas interpretaciones, la promoción del bien común sigue siendo en la actualidad un objetivo clave del Estado en el ideario democrático y un tema recurrente de la ética pública. En lo que sigue, se reconstruye críticamente el concepto tradicional de bien común, haciendo especial referencia a las obras de Platón, Aristóteles y Santo Tomas, con el fin de sentar bases para una nueva comprensión de la idea de bien común en sociedades pluralistas y democráticas.With the concept of commom good reference has been made, along history, to those material and immaterial goods which are not circumscribed to a person, but remit to each and every member of society. Among those goods, basic elements for biological human survival, such as air and water, are usually included, but also the right to participate of the profits of cultural goods. In some cases, commom good has been made equivalent to common wellfare; in others, to the summation of particular interests or to the benefit of the majority. Beyond the diverse interpretations, the promotion of common good continues at present to be a key aim of State in the democratic ideary and a recurrent issue in public ethics. In what follows, the concept of traditional common good has been reconstructed, making special reference to the

  1. In Memory of Han Suyin

    Institute of Scientific and Technical Information of China (English)

    Chen; Yixin

    2014-01-01

    <正>Tn sunny days,I often like to stroll alone along Wukang Road in the former French concession in Shanghai.Every time I pass by the former residence of renowned writer Ba Jin,I will stop and raise my head looking at this garden villa of simple style and its balcony bathed in warm sunshine,prompting many recollections to throng my mind.Then,the scene will appear before my eyes of Han Suyin and I visiting Ba Jin,sitting in the sunny drawing room,sipping tea and chatting

  2. La comunidad de bienes como forma jurídica de empresa

    OpenAIRE

    Vaticón Fernández, José Antonio

    2014-01-01

    Este trabajo trata sobre la Comunidad de Bienes, regulada en el los artículos 396 al 406 del Código Civil. Las características que definen a una Comunidad Bienes son las siguientes: 1. No tiene personalidad jurídica propia. 2. Hace falta un contrato privado para poder ejercer la actividad. 3. No se exige una aportación mínima de dinero. 4. Se exige un mínimo de dos socios. 5. La responsabilidad hacia terceros es ilimitada. En conclusión, la Comunidad de Bienes no es la...

  3. Hans Blix appointed Director General

    International Nuclear Information System (INIS)

    On 1 December 1981, Dr Hans Blix took office as Director General of the International Atomic Energy Agency in succession to Dr Sigvard Eklund who has headed the IAEA since 1961. The Agency's Board of Governors nominated Dr Blix by acclamation on 26 September. His appointment was unanimously approved by the final session of the 25th regular session of the General Conference of the IAEA the same day. The President of the Conference, Ambassador Manaspas Xuto, administered the oath of office to Dr Blix at the final plenary meeting that day. Hans Blix was born in 1928 in Uppsala He studied at the University of Uppsala, at Columbia University, where he was also a research graduate and at Cambridge, where he received his Ph D In 1959 he became Doctor of Laws at the Stockholm University and in 1960 was appointed associate professor in international law. From 1963 to 1976 Dr Blix was Head of Department at the Ministry for Foreign Affairs and served as Legal Adviser on International Law. In 1976 he became Undersecretary of State at the Ministry for Foreign Affairs in charge of international development co-operation He was appointed Minister for Foreign Affairs in October 1978 In September 1979 he was again appointed Undersecretary of State at the Ministry for Foreign Affairs in charge of international development co-operation. Since 1961 he has been a member of Sweden's delegation to the United Nations General Assembly, and from 1962 to 1978 a member of the Swedish delegation to the Conference on Disarmament in Geneva. He has written several books on subjects associated with international and constitutional law and was leader of the Liberal Campaign Committee in favour of retention of the Swedish nuclear energy program in the referendum in 1980

  4. Non-Toxic HAN Monopropellant Propulsion Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Non-toxic monopropellants have been developed that provide better performance than toxic hydrazine. Formulations based on hydroxylammonium nitrate (HAN) have...

  5. COLONIALISM, HAN & ECO-THEOLOGY

    Directory of Open Access Journals (Sweden)

    Grace Ji-Sun Kim

    2013-06-01

    Full Text Available Today, nations exhibit imperial behaviour but not like the ancient agriculture driven landed empires or the 18-19th century mercantile empires. The land and trade divisions are not as clearly segregated as in the earlier ones, but Imperial nations do exist and do control other nations. Imperialism and colonialism has devastating effects on our world. It has nurtured self-worth through the accumulation of worldly goods for the purposes of serving their own interests and exploiting others for the sole purpose of self-gain. This is devastating not only to human beings but to the whole ecology of the planet. Consumerism drives trade, but consumer buying is now like an unchained beast with tooth and claw causing han for the exploited as well as the resources of the planet. Eco-theologians and feminist theologians examine the devastating effects to help ensure that we are seriously determined to preserve the planet. We will examine ways of rethinking and reimagining our errors and how we can work towards the right direction for a safer, sustainable planet. doi: 10.7833/111-1-15

  6. TRASMISIÓN DE BIENES Y REGISTRO DE LA PROPIEDAD EN ESPAÑA (SEGUNDA PARTE

    Directory of Open Access Journals (Sweden)

    Joaquín Sánchez Cebrián

    2009-01-01

    Full Text Available La circulación de los bienes en el tráfico jurídico por la voluntad de los particulares es un tema crucial que interesa, no sólo a las partes del contrato, sino, a todos en general, y, en particular, a los acreedores del transmitente o del adquirente y a los terceros adquirentes de derechos sobre el bien. En este trabajo se analizará el régimen de trasmisión de los bienes por negocio inter vivos en el Derecho español, dentro del marco europeo, y con particular referencia a la trasmisión inmobiliaria. España adopta un peculiar sistema de trasmisión de los bienes porque se establecen reglas genéricas cuya aplicación se da con independencia de la naturaleza mueble o inmueble del bien; pero a su lado se superponen otras que tratan de fijar los efectos de la publicidad registral inmobiliaria. La coordinación entre dichas reglas produce un original resultado, que puede constituir el punto de encuentro de los diversos sistemas registrales europeos.

  7. L’éducation, un bien commun très particulier

    OpenAIRE

    Proulx, Jean-Pierre

    2015-01-01

    Dans ce texte, le président du Conseil supérieur de l’éducation discute de celle-ci en tant que bien commun, mais également en tant que bien particulier. Il démontre l’importance du rôle de l’État en matière d’accessibilité à l’éducation. Ainsi, en pratique, seul l’État, en tant que responsable premier du bien commun et de la justice distributive, est capable d’assurer cette accessibilité à tous et en pleine égalité, grâce aux impôts et aux taxes qu’il perçoit des citoyens et des entreprises....

  8. Los bienes prestados: Estrategias feudales de consolidación señorial

    OpenAIRE

    Jular Pérez-Alfaro, Cristina

    1999-01-01

    Este artículo analiza las operaciones denominadas prestimonia en los textos medievales: un tipo particular de cesión de bienes, principalmente de tierras, realizada en calidad de préstamo de por vida, por una autoridad señorial a otra entidad y sirviendo el usufructo de los bienes concedidos como pago de lo adquirido. Tema con cierta tradición historiográfica, se pretende ahora someterlo a un nuevo cuestionario, introducirlo en la conceptualización amplia de "lo prestado" y ver resultados con...

  9. Estudio de las recurrencias y de la supervivencia en los enfermos con tuberculosis que han completado el tratamiento en la ciudad de Barcelona

    OpenAIRE

    Millet Vilanova, Juan Pablo

    2012-01-01

    ANTECEDENTES Se conocen bien los factores asociados a las recidivas en tuberculosis (TB). Sin embargo, las tasas de recurrencia y sus factores asociados han sido escasamente descritos, especialmente en curados. Existen además, pocos datos sobre la supervivencia a largo plazo de los pacientes que completaron el tratamiento de la TB. El objetivo de esta tesis es el conocer la incidencia y los factores predictores de tener una recurrencia en TB y de morir, en diferentes cohortes de pacientes ...

  10. bien reconocida

    Directory of Open Access Journals (Sweden)

    N. Prat

    2015-01-01

    Full Text Available En el año 2014 se conmemora el décimo aniversario de la muerte del Profesor Ramón Margalef. En este artículo se hace un repaso a las publicaciones realizadas por el Dr. Margalef, que llegan a un total de 563 trabajos. La temática dominante de los mismos es la ecología acuática, tanto marina como de agua dulce, y mayormente centrados en los estudios de plancton. Sus trabajos están sobre todo publicados en castellano, en catalán y, en menor medida en inglés, en casi 100 revistas diferentes de todo tipo (desde revistas divulgativas a científicas. Destacan por número los artículos publicados en las revistas “Investigación Pesquera” y “Publicaciones del Instituto de Biología Aplicada”, aunque numéricamente los capítulos de libros y las actas de congresos dominan sus trabajos. De todos estos trabajos, 383 se encuentran citados en la “Web of Science” con un promedio cercano a las 100 citas por año, destacando su trabajo de 1978 sobre las formas de vida del fitoplancton, que sigue siendo muy citado (más de 50 citas por año y con tendencia incluso a crecer en el tiempo. Es destacable el poco conocimiento que se tiene de sus libros (con excepción del primero que publicó en inglés titulado “Perspectives in Ecological Theory”, de 1968. A pesar del gran reconocimiento internacional que tuvo Margalef en vida, hoy en día parece que su obra es en gran parte desconocida por los ecólogos del siglo XXI. Su nombre ha desaparecido de los libros de texto de ecología y una de sus grandes aportaciones a la ecología moderna (introducir la teoría de la información en Ecología y el índice de Shannon-Weaver como medida de diversidad no aparece en los manuales de ecología.

  11. VALORACIÓN ECONÓMICA DE BIENES AMBIENTALES POR BENEFICIARIOS CIRCUNDANTES Y NO CIRCUNDANTES

    Directory of Open Access Journals (Sweden)

    Mauricio G Villena

    2013-06-01

    Full Text Available La pregunta básica de investigación detrás de este trabajo es cómo difiere la valoración económica de un bien ambiental considerando beneficiarios circundantes (quienes viven cerca del bien en cuestión y no circundantes (quienes habitando el país donde se encuentra el bien, viven en poblaciones distantes y por tanto disfrutan esporádicamente de los beneficios provistos por el bien ambiental. En particular, en este documento se valora económicamente el Bosque de Algarrobos de la comunidad de Tiataco (Bolivia, realizando un análisis comparativo entre beneficiarios circundantes (familias residentes en la comunidad de Tiataco y beneficiarios no circundantes (familias residentes en la ciudad de Cochabamba, a 35 Km de Tiataco, a través del Método de Valoración Contingente con formato binario. Se estimaron medidas de cambio en el bienestar para ambos grupos, empleando estimaciones paramétricas y no paramétricas. Posteriormente, estas medidas se compararon estadísticamente por medio de la construcción de intervalos de confianza (entre estimaciones paramétricas y no paramétricas de cada población y entre ambas poblaciones. Por último, se identificaron los componentes del valor económico total que los beneficiarios tanto circundantes como no circundantes asignaron al bosque.

  12. Notas sobre Pasinetti, los bienes autoreproducibles y el “factor” trabajo

    OpenAIRE

    Alfons Barceló

    2006-01-01

    Esta nota pretende mostrar que son insatisfactorios los supuestos asumidos por Pasinetti sobre a) la presunta irrelevancia económica de las tasas propias de reproducción de los bienes autorreproducibles; b) la conceptualización del “trabajo” como “factor último de la producción”.

  13. Repensando los bienes comunes: análisis socio-técnico sobre la construcción y regulación de los bienes comunes

    Directory of Open Access Journals (Sweden)

    Ariel Vercelli

    2008-09-01

    Full Text Available El presente artículo analiza los bienes comunes desde una perspectiva socio-técnica. Puntualmente, invita a repensarlos en función de algunos cambios tecnológicos recientes. A partir de esta perspectiva es posible observar cómo los bienes comunes son parte de un proceso continuo de luchas, negociaciones y redefiniciones políticas entre diferentes grupos de actores. Analiza como estas luchas políticas son parte de un proceso de co-construcción entre el diseño tecnológico y las nuevas formas de regulación.This article discusses the commons ("common goods" from a socio-technical view. Specifically, it invites us to rethink them in the light of some recent technological changes. From this perspective it is possible to see how the commons are part of a continuous process of struggles, negotiations and political re-definitions among different groups of players. Analyze how these political struggles are part of a process of co-construction between the design of technologies and new forms of regulation.

  14. Creating a New Chinese Cyber-Celebrity : A Cultural Analysis of Han Han's Blog as Web-based Media Spectacle

    OpenAIRE

    Berg, DPhil (Oxon), Daria; Strafella, Giorgio

    2014-01-01

    Novelist and race-car driver Han Han stars as the world's most popular blogger, boasting 595 million hits. China has emerged as the world's largest Internet population with 591 million netizens and a 44% penetration rate, rapidly increasing the number of Chinese citizens able to exchange information and opinions through non-official channels. Using Han Han as a case study, this paper aims first, to analyse how China's cybersphere creates a new type of celebrity; and second, how Han Han's blog...

  15. Sweating method in Shang Han Lun

    OpenAIRE

    Can, Engin; Cheng, Ming Zhao

    2010-01-01

    Sweating method(汗法)is the first therapeutic methods described in Shang Han Lun (伤寒论Treatise on Cold Damage Disease)by Zhang Zhongjing in the East Han Dynasty (3rd century AD, about 200-219 AD). This method is mainly used for treating exterior syndrome of Taiyang Disease (Greater Yang) Disease. Its first representative formula is Mahuang Tang (麻黄汤 Ephedra Decoction). Additionally, there are many other formulas that can also be classified in the category of sweating method to treat ass...

  16. Santé et biens communs : un regard de juriste.

    Directory of Open Access Journals (Sweden)

    Isabelle Moine-Dupuis

    2010-11-01

    Full Text Available La santé constitue un domaine dans lequel les notions de bien commun ou de bien public mondial sont particulièrement pertinentes. Il faut cependant préciser de quels biens il est question. A titre d’exemple, le droit français comporte des notions susceptibles de qualifier le droit aux soins (comme droit inaliénable, ou le médicament, objet de propriété intellectuelle comme de propriété « traditionnelle ». Un droit international des biens de santé peut de la même manière être fondé sur un droit d’usage de chacun sur la molécule qui est la même dans le médicament générique et celui de marque. Une procédure d’accès équivalent aux produits, brevetés ou non, pourrait être mise en œuvre par principe dès la découverte, afin de parvenir rapidement à des prix équitables.Health is a field particularly suitable for notions as commons or public goods. It is necessary however to know which goods may be concerned. For instance, French lawyers use concepts which can be used in order to qualify right to care (as an inalienable right, or medicine as an object of intellectual property as well as “traditional” one. An international law for health goods could be also based on a right of use for each person on the molecule which is the same in the generic drug or in the patented one. A process of “equivalent access” to licensed or free products could be initiated, from the discovery itself to the use, in order to obtain rapidly fair prices.

  17. Obituary: Hans Albrecht Bethe, 1906-2005

    NARCIS (Netherlands)

    R. Wijers

    2007-01-01

    One of the unquestioned giants of physics and astrophysics, Hans Bethe, died on 6 March 2005, at the venerable age of 98, in his home town of Ithaca, New York. Seven decades of contributing to research and a Nobel Prize for his work on stellar hydrogen burning make a listing of his honors superfluou

  18. HAN-Based Monopropellant Technology Development

    Science.gov (United States)

    Reed, Brian

    2002-01-01

    NASA Glenn Research Center is sponsoring efforts to develop technology for high-performance, high-density, low-freezing point, low-hazards monopropellant systems. The program is focused on a family of monopropellant formulations composed of an aqueous solution of hydroxylammonium nitrate (HAN) and a fuel component. HAN-based monopropellants offer significant mass and volume savings to small (less than 100 kg) satellite for orbit raising and on-orbit propulsion applications. The low-hazards characteristics of HAN-based monopropellants make them attractive for applications where ground processing costs are a significant concern. A 1-lbf thruster has been demonstrated to a 20-kg satellite orbit insertion duty cycle, using a formulation compatible with currently available catalysts. To achieve specific impulse levels above those of hydrazine, catalyst materials that can withstand the high-temperature, corrosive combustion environment of HAN-based monopropellants have to be developed. There also needs to be work done to characterize propellant properties, burning behavior, and material compatibility. NASA is coordinating their monopropellant efforts with those of the United States Air Force.

  19. Hans Pöhl - Estlandssvenskarnas hövding = Hans Pöhl - rannarootslaste eestvõitleja / Torkel Jansson

    Index Scriptorium Estoniae

    Jansson, Torkel, 1947-

    2011-01-01

    Raamatututvustus: Hans Pöhl - Estlandssvenskarnas hövding : en biografi över Hans Pöhl (1876-1930), estlandssvenskarnas främste företrädare och ledare = Hans Pöhl - rannarootslaste eestvõitleja : Hans Pöhli (1876-1930), Eesti rootslaste vaimse liidri ja valgustaja elulugu. (Stockholm ; Tallinn, 2010)

  20. Hans Teiv : mina sellel kohal igavuse üle ei kurda / Hans Teiv ; interv. Heli Salong

    Index Scriptorium Estoniae

    Teiv, Hans

    2004-01-01

    Saare maavanema kohusetäitja ja kandidaat Hans Teiv hindab oma võimalusi saada ametisse kinnitatud, räägib oma tegevusest maavalitsuse osakonnajuhataja ja maakonna juhina ning tutvustab Saaremaa arenguvisioone

  1. Hans Lepp : ainult tänu kodueestlastele on Eesti olemas / Hans Lepp ; interv. Kalev Vilgats

    Index Scriptorium Estoniae

    Lepp, Hans, 1950-

    2007-01-01

    Rootsi instituudi praegune kultuurinõunik Hans Lepp töötas esimese kultuuriatasheena taas avatud Rootsi suursaatkonnas. Töötamisest Rootsi instituudis, riigi välispoliitikast, suhetest Venemaaga, aprillisündmustest jm

  2. Transforming han: a correlational method for psychology and religion.

    Science.gov (United States)

    Oh, Whachul

    2015-06-01

    Han is a destructive feeling in Korea. Although Korea accomplished significant exterior growth, Korean society is still experiencing the dark aspects of transforming han as evidenced by having the highest suicide rate in Asia. Some reasons for this may be the fragmentation between North and South Korea. If we can transform han then it can become constructive. I was challenged to think of possibilities for transforming han internally; this brings me to the correlational method through psychological and religious interpretation. This study is to challenge and encourage many han-ridden people in Korean society. Through the psychological and religious understanding of han, people suffering can positively transform their han. They can relate to han more subjectively, and this means the han-ridden psyche has an innate sacredness of potential to transform. PMID:25252804

  3. OF THE COMMON GOOD TO THE COMMON GOOD OF HUMANITY. DE LOS BIENES COMUNES AL BIEN COMÚN DE LA HUMANIDAD.

    Directory of Open Access Journals (Sweden)

    François Houtart.

    2014-06-01

    éndum sobre el agua (uno de los bienes comunes en Italia, la Fundación Rosa Luxemburgo tomó la decisión de organizar una Conferencia sobre el concepto del Bien Común de la Humanidad, para promover una reflexión sobre los vínculos entre las dos nociones y de integrar las reivindicaciones y las luchas sociales para un cambio de sociedad, escenario en el que se enmarca éste artículo.

  4. An interview with Mark G. Hans.

    Science.gov (United States)

    Hans, Mark G; Nojima, Matilde da Cunha Gonçalves

    2014-01-01

    It is a great honor to conduct an interview with Professor Mark G. Hans, after following his outstanding work ahead of the Bolton-Brush Growth Study Center and the Department of Orthodontics at the prestigious Case Western Reserve School of Dental Medicine (CWRU) in Cleveland, Ohio. Born in Berea, Ohio, Professor Mark Hans attended Yale University in New Haven, CT, and earned his Bachelor of Science Degree in Chemistry. Upon graduation, Dr. Hans received his DDS and Masters Degree of Science in Dentistry with specialty certification in Orthodontics at Case Western Reserve University. During his education, Dr. Hans’ Master’s Thesis won the Harry Sicher Award for Best Research by an Orthodontic Student and being granted a Presidential Teaching Fellowship. As one of the youngest doctors ever certified by the American Board of Orthodontics, Dr. Hans continues to maintain his board certification. He has worked through academics on a variety of research interests, that includes the demographics of orthodontic practice, digital radiographic data, dental and craniofacial genetics, as obstructive sleep apnea syndrome, with selected publications in these fields. One of his noteworthy contributions to the orthodontic literature came along with Dr. Donald Enlow on the pages of “Essentials of Facial Growth”, being reference on the study of craniofacial growth and development. Dr. Mark Hans’s academic career is linked to CWRU, recognized as the renowned birthplace of research on craniofacial growth and development, where the classic Bolton-Brush Growth Study was historically set. Today, Dr. Hans is the Director of The Bolton-Brush Growth Study Center, performing, with great skill and dedication, the handling of the larger longitudinal sample of bone growth study. He is Associate Dean for Graduate Studies, Professor and Chairman of the Department of Orthodontics, working in clinical and theoretical activities with students of the Undergraduate Course from the School of

  5. Hans Freudenthal als docent en collega

    OpenAIRE

    Verhulst, Ferdinand; Verhoef, Nellie

    2010-01-01

    Hans Freudenthal heeft een belangrijke invloed gehad op de ontwikkeling van het basiswiskundeonderwijs. Niet minder belangrijk was zijn activiteit als docent en onderzoeker gedurende tientallen jaren op het Mathematisch Instituut van de Universiteit Utrecht. Hoe waren toen zijn ideeën over onderwijs, hoe was hij als collega en hoe waren zijn colleges? Nellie Verhoef en Ferdinand Verhulst interviewden voormalige collega’s en studenten van Freudenthal.

  6. Hans Zinsser: a tale of two cultures.

    Science.gov (United States)

    Summers, W C

    1999-01-01

    Hans Zinsser, president of the Society of American Bacteriologists in 1926, was known as much for his literary and textbook writing as for his scientific contributions. He was a widely known scientist and person of letters. His early interests in poetry and other forms of literature were maintained and developed during his career as a microbiologist, and his most enduring legacy is based on his writing about microbiology for a general readership as well as his reflective and philosophical autobiography. PMID:11049165

  7. Hans Strand:大地诗人

    Institute of Scientific and Technical Information of China (English)

    烁朱; Hans; Strand

    2012-01-01

    Hans Strand与很多摄影家不同。在他整个青少年时期,都和摄影没有任何瓜葛,第一次拍照甚至到了大学快毕业的时候。但是,这并不妨碍他后来成为举世瞩目的自然摄影家。这位1955年出生于瑞

  8. Die biene und ihre produkte in der kunst und im alltagsleben (Fruhchristliche und byzantinische Zeit

    Directory of Open Access Journals (Sweden)

    Liveri Angeliki

    2010-01-01

    Full Text Available Die vorliegende Arbeit ist in zwei Teile geteilt: den kunst- und kulturhistorischen Teil. Im ersten Teil werden Darstellungen uber Bienen Bienenzucht, Honig und Wachs seit der fruhchristlichen bis zur spatbyzantinischen Zeit vorgefuhrt. Daher ist es als Beitrag in der "Ikonographie" der Biene wahrend dieser Zeit zu verstehen. Im kulturhistorischen Teil werden Informationen uber die Bienenzucht, den Handel mit Honig und Wachs sowie ihre vielfaltige Anwendung von der byzantinischen Gesellschaft an Hand der primaren Quellen, des Standes der Forschung und der archaologischen Funden erwahnt. Damit ist erwunscht ein moglichst gutes Bild der byzantinischen Bienenzucht wieder zu geben und die Nutzung der Bienenprodukte in Byzanz anschaulich zu machen.

  9. Adolescentes intelectualmente bien dotados. Una investigación en la provincia de Toledo.

    OpenAIRE

    Hume Figueroa, Miriam; Sánchez Núñez, María Trinidad

    2004-01-01

    Este artículo sintetiza los resultados de una investigación sobre identificación de alumnos intelectualmente bien dotados de 1º de E.S.O. en la provincia de Toledo, que comienza en mayo de 1993 y que todavía está en curso. Mediante el método de filtrado o screening aplicamos la prueba Matrices Progresivas de Raven a casi 6.000 alumnos del curso mencionado. Escogimos la franja de alumnos que se situaba muy por encima de la media, según los resultados de dicha prueba, para realizar un estudio m...

  10. Restauración del capital natural: sin reservas no hay bienes ni servicios

    OpenAIRE

    Aronson, James; Renison, Daniel; Rangel Churio, Jesús Orlando; Levy Tacher, Samuel; Ovalle Molina, Carlos; Pozo Lira, Alejandro del

    2007-01-01

    Una de las ideas más innovadoras y atractivas que se están acuñando en la actualidad está relacionada con la necesidad que tiene la humanidad de preservar y manejar los recursos naturales - o capital natural - remanente e invertir en la restauración del capital natural (RCN) degradado para reincorporarlo a la cadena de bienes y servicios que la sociedad requiere. En este artículo, presentamos definiciones y conceptos básicos, para mostrar como la RCN es un enfoque más amplio en re...

  11. Restauración del Capital Natural: sin reservas no hay bienes ni servicios

    OpenAIRE

    Aronson, J.; D. Renison; Rangel-Ch, J. O.; S. Levy-Tacher; Ovalle, C.; del Pozo, A.

    2007-01-01

    Una de las ideas más innovadoras y atractivas que se están acuñando en la actualidad está relacionada con la necesidad que tiene la humanidad de preservar y manejar los recursos naturales o capital natural - remanente e invertir en la restauración del capital natural (RCN) degradado para reincorporarlo a la cadena de bienes y servicios que la sociedad requiere. En este artículo, presentamos definiciones y conceptos básicos, para mostrar como la RCN es un enfoque más amplio en relación al pr...

  12. El reconocimiento de los bienes de dominio público: El caso de los municipios portugueses

    Directory of Open Access Journals (Sweden)

    Susana Catarino Rua

    2016-02-01

    Full Text Available Objeto: Este trabajo tiene por objetivos analizar el mencionado en el POCAL (1999, en las NICSP del IPSASB y en diversas opiniones doctrinales con respecto al reconocimiento de los bienes de dominio público (BDP, así como verificar si existen problemas inherentes al reconocimiento de los BDP en Portugal, superables con la adopción de las NICSP. Diseño/metodología/Enfoque: Para este estudio, fue efectuada una revisión de literatura, de la posición del POCAL (1999, de las NICSP del IPSASB, y de la perspectiva doctrinal, con respecto al reconocimiento de los bienes de dominio público. Además, se realizó un estudio de la evolución de los valores de los bienes de dominio público, de los años 2006 a 2013, del total de los 308 municipios portugueses, para concluir acerca de la existencia de dificultades en el reconocimiento de estos activos y de la necesidad de adoptar los normativos internacionales. Aportaciones y Resultados: En algunos municipios portugueses, el proceso de inventario aún no está concluido, existiendo dificultades con respecto al reconocimiento de los BDP. Dichas dificultades resultan de que el POCAL (1999 no presenta los requisitos para el reconocimiento de los activos; problema superado en la NICSP nº 17 del IPSASB (2006b, que refiere esos requisitos. Adoptar un nuevo Sistema de Normalización Contable aplicable a la Administración Pública (SNC-AP, basado en las NICSP, puede ser la solución para dichas cuestiones, introduciendo criterios a considerar en el reconocimiento de los activos, que aseguren la comparabilidad de la información y de los valores del patrimonio de los municipios portugueses. Limitaciones: La inexistencia de criterios de reconocimiento a seguir por los municipios trae limitaciones al nivel de la comparabilidad de los valores de los diferentes componentes del activo presentados por los varios municipios. Valor añadido: Este trabajo nos enseña que, en Portugal, aún existen problemas con

  13. Determinantes de los precios internacionales de los bienes básicos

    OpenAIRE

    Carolina Arteaga; Joan Granados; Jair Ojeda

    2012-01-01

    En este trabajo se analiza la respuesta dinámica de los precios de los bienes básicos más relevantes para la evolución de la inflación en Colombia ante choques en un conjunto de sus determinantes. El documento está basado en modelos VAR estructurales en los cuales los choques exógenos son identificados mediante restricciones a los efectos contemporáneos entre las variables del sistema. Para la estimación se utilizan datos trimestrales para el periodo 1980q1 a 2010q3. De acuerdo con los result...

  14. Memoria sobre la Red de Estudio y Enseñanza Interdisciplinar del Gobierno del Bien Común

    OpenAIRE

    Ortiz García, Mercedes; Garay Montañez, Nilda; Gómez Calvo, Verónica; Hidalgo Moratal, Moisés; Carmen PASTOR SEMPERE; Romero-Tarín, Adela

    2015-01-01

    El presente trabajo en red docente ha servido para cuestionar y proponer la reformulación de la enseñanza y la investigación universitaria a partir del “gobierno del bien común”. Desde la Red se ha pretendido reformular el concepto de “bien público” como “bien común” para recalcar el uso común de dichos bienes y la necesidad de su conservación en buen estado para asegurar dicho uso, y evitar las peligrosas “privatizaciones encubiertas”. De ahí que nuestra Red a través de sus distintas discipl...

  15. The philosophy of Hans-Georg Gadamer / Wolfgang Drechsler

    Index Scriptorium Estoniae

    Drechsler, Wolfgang, 1963-

    1998-01-01

    Rets.rmt.: The philosophy of Hans-Georg Gadamer : a review of the philosophy of Hans-Georg Gadamer / Lewis Edwin Hahn, ed. Chicago and La Salle, IL: Open Court, 1997. (The Library of Living Philosophers, vol. XXIV)

  16. Restauración del Capital Natural: sin reservas no hay bienes ni servicios

    Directory of Open Access Journals (Sweden)

    J. Aronson

    2007-01-01

    Full Text Available Una de las ideas más innovadoras y atractivas que se están acuñando en la actualidad está relacionada con la necesidad que tiene la humanidad de preservar y manejar los recursos naturales o capital natural - remanente e invertir en la restauración del capital natural (RCN degradado para reincorporarlo a la cadena de bienes y servicios que la sociedad requiere. En este artículo, presentamos definiciones y conceptos básicos, para mostrar como la RCN es un enfoque más amplio en relación al propuesto en la restauración ecológica de ecosistemas naturales. Damos a conocer estudios de caso, como ejemplos del enfoque de la RCN, y su impacto sobre el suministro de bienes y servicios en Argentina, Colombia, México y Chile. Terminamos con una breve discusión y algunas recomendaciones para la investigación y el desarrollo de la RCN a nivel local, regional y global.

  17. Vite et bien 1 A1/A2 : méthode rapide pour adultes

    CERN Document Server

    Miquel, Claire

    2009-01-01

    Vite et bien s'adresse à des adultes pressés et impatients de communiquer avec succès en français ! Le vocabulaire est simple et usuel et les thèmes, variés, pour faire face, efficacement, à toutes les situations de la vie quotidienne et professionnelle. Livre + CD audio et corrigés inclus. La méthode rapide Vite et bien 1 permet à la fois d'apprendre le français et de découvrir la réalité de la vie en France, les différences culturelles, le langage de la vie quotidienne, le tout en un temps record. En effet, le premier volume couvre, en vingt unités, les niveaux A1 et A2 du Cadre Européen de référence (CECR). Ainsi, en 100 à 120 heures de cours selon les publics, il sera possible d'acquérir une bonne base de grammaire et de vocabulaire, claire, simple, fonctionnelle, et de se sentir à l'aise dans la communication orale et écrite. L'ouvrage s'adresse aux vrais et et aux faux débutants, constituant donc un outil d'apprentissage et/ou de rafraîchissement des connaissances. Chacune des v...

  18. Rannarootslaste suurmees Hans Pöhl / Olev Liivik

    Index Scriptorium Estoniae

    Liivik, Olev, 1975-

    2011-01-01

    Arvustus: Estlandssvenskarnas hövding. En biografi över Hans Pöhl (1876-1930), estlandssvenskarnas främste företrädare och ledare = Hans Pöhl - rannarootslaste eestvõileja : Hans Pöhl (1876-1930), Eesti rootslaste vaimse liidri ja valgustaja elulugu. Stockholm, 2010

  19. Hans Kruusi seotusest kodu-uurimisliikumisega / Eva Maaring

    Index Scriptorium Estoniae

    Maaring, Eva

    2011-01-01

    Uks kodu-uurimise valdkonda paotus Hans Kruusile Tartu Õpetajate Seminaris õppides 1910. aastal. 1920. aastatel elavnes Tartus teaduslik kodu-uurimine, hakkasid ilmuma koguteosed. Ajaloolasena oli nendes oma osa H. Kruusil. 1958. aastal sai Hans Kruusist Eesti NSV TA juures tegutseva kodu-uurimise komisjoni esimees. Hans Kruusi tabavaid ütlusi

  20. Bulgaria: Novi Han radioactive waste repository

    International Nuclear Information System (INIS)

    The Novi Han radioactive waste repository is the only national radioactive waste disposal site in Bulgaria. It is located in Losen mountain, 6.5 km from the small village of Novi Han and 35 km from the capital, Sofia. The repository accepts radioactive waste generated from nuclear applications in industry, medicine, research and education. The facility was constructed according to a modified Soviet design (type TP-4891). Its construction licence was issued in 1959 and that for commissioning in 1964. The repository was specially built for the needs of the IRT-2000 research reactor operated by the Institute of Physics and other academic and medical facilities. In 1959, the Government appointed the Physical Institute of the Bulgarian Academy of Sciences, whose successor is now the Institute for Nuclear Research and Nuclear Energy (INRNE), as the central authority for the collection and disposal of radioactive waste from nuclear applications. The Novi Han repository site covers an area of 4.25 ha.1 The site is divided into two areas separated by a fence. One area contains the administrative buildings, garage and maintenance shops. The other contains the disposal facilities, radiochemical laboratory and decontamination station. The repository consists of (1) a concrete vault for low and intermediate level solid wastes, which consists of 3 separate cells with a total volume of 237 m3, (2) a concrete vault for biological wastes with a volume of 80 m3, (3) four steel tanks for storage of low level liquid wastes with a total volume of 48 m3, (4) a special 1 m3 concrete vault for spent sealed sources and (5) a concrete trench for solid waste, which consists of 7 separate units with a total volume of 200 m3. Waste acceptance criteria follow Regulation No. 7 of the Committee on the Use of Atomic Energy for Peaceful Purposes on Collection, Treatment, Storage, Transport and Disposal of Radioactive Wastes in the Territory of the Republic of Bulgaria. They take into account origin

  1. Musique du mal, musique du bien dans le théâtre baroque

    OpenAIRE

    Wolf, Robert Erich

    2012-01-01

    Si on cherche le fondement moral commun à la plupart des pièces de théâtre baroques, on le trouvera, il me semble, dans le conflit entre le Bien et le Mal. À l’époque baroque ce conflit prend la forme du débat, du dialogue, de la dialectique ; et, comme il arrive souvent dans l’art, l’opposition entre valeurs morales - ou psychologiques, ce qui au théâtre est équivalent - détermine en grande partie la forme de la pièce : on peut dire même qu’elle forme la pièce. Ce qui distingue l’art théâtra...

  2. Aux vrais beaux biens : souvenirs autour de Max Ophuls

    OpenAIRE

    Müller, Martina

    2007-01-01

    En 1989 j’ai interrogé des collaborateurs de Max Ophuls qui avaient travaillé avec lui au théâtre, à la radio et au cinéma. Ces entretiens ont été enregistrés pour mon documentaire de quatre-vingt dix minutes : Max Ophuls. Aux vrais beaux biens, produit par la Westdeutscher Rundfunk, télévision allemande de Cologne. Cette émission – diffusée en 1990 et jamais présenté en France – est composée d’interviews et de commentaires de séquences. En outre on y entend la voix de Max Ophuls et on le voi...

  3. The global warming, public goods and carbon market; Calentamiento global, bienes publicos y mercado de carbono

    Energy Technology Data Exchange (ETDEWEB)

    Quadri de la Torre, Gabriel [EcoSecurities (Mexico)

    2007-07-15

    The global warming is an issue of the public goods, and demands an outstanding multilateral action, which must to ensure both efficiency and unchanging transition towards an economy of low intensity of carbon. The new system, which is going to replace the Kyoto Protocol, will have compromises for the developing countries and deep implication in the relative competitivity of the nations and companies. [Spanish] El calentamiento global es un problema de bienes publicos que exige una extraordinaria accion multilateral. Esta debe asegurar eficiencia y una transicion fluida hacia una economia de baja intensidad de carbono. El nuevo sistema que sucedera al Protocolo de Kyoto significara compromisos para los paises en vias de desarrollo, y tendra profundas implicaciones en la competitividad relativa de naciones y empresas.

  4. Tülikas meediademokraat Hans H. Luik / Hans H Luik ; interv. Jaanika Merilo

    Index Scriptorium Estoniae

    Luik, Hans H., 1961-

    2006-01-01

    Ekspress Grupi omanik ja nõukogu liige Hans H. Luik vastab küsimustele, mis puudutavad Ekspress Grupi võimlikku börsile minekut, meediaportfelli laiendamist ning tema vastu suunatuid rünnakuid. Skeem: Ekspress Grupp. Tabelid: Eesti Ekspressi majandusnäitajad; Ekspress Grupi majandusnäitajad. Kommenteerivad: Tuomas Siltala, Karoly Kirber, Lauri Lind ja Peeter Koppel

  5. HANS JONAS: CONSERVACIÓN DE LA NATURALEZA, CONSERVACIÓN DE LA VIDA

    Directory of Open Access Journals (Sweden)

    MARIO BURGUI BURGUI

    2015-01-01

    Full Text Available En este artículo se tratan varios problemas relacionados entre sí que el filósofo alemán Hans Jonas estudió. El primero de ellos es la necesidad de una ética específica dedicada a la dimensión moral de los problemas ambientales, desde una perspectiva distinta a la tradicional. El segundo problema ocupa un lugar central en la discusión en ética ambiental: el valor de la naturaleza. ¿Tiene valor intrínseco o sólo un valor instrumental (para satisfacer los intereses del ser humano? A este respecto se expone la tesis de Jonas según la cual la naturaleza no sólo tiene valor intrínseco, sino que constituye un bien en sí misma. Y el tercer problema es la derivación de normas morales y el papel del hombre en esta ética que reconoce un bien en sí en la naturaleza. Según Jonas, el ser humano no se ve devaluado al reconocer el valor intrínseco de la naturaleza, pues la excepcionalidad y el valor de aquel son incuestionables. A partir de estas tres cuestiones centrales, se resalta la importancia de buscar los lazos que unen la bioética y la ética ambiental para encarar la crisis ambiental, social y económica del momento presente.

  6. The tainted legacy of Hans Reiter.

    Science.gov (United States)

    Panush, Richard S; Paraschiv, Diana; Dorff, Rabbi Elliot N

    2003-02-01

    There is more than ample evidence that Hans Reiter, whose name has been eponymously linked to a rheumatologic syndrome, was a Nazi war criminal. He was responsible for heinous atrocities that violated the precepts of humanity, ethics, and professionalism. The authors suggest that Reiter's legacy is sufficiently tainted that the professional and ethical position of the medical community should be to no longer afford him this recognition. He should be remembered symbolically to remind us of our moral and professional responsibilities to prevent the kind of "experiments" he perpetrated as Director of the Nazi office for such matters. Medicine is a moral enterprise. Physicians serve to promote the welfare of their patients. Hans Reiter and others like him who have behaved in such a manner have acted beyond the pale of acceptable human behavior. These crimes by Reiter and others like him were transcendently aberrant and evil. We regard Reiter and others like him as tainted. We see no acceptable rationale to preserve any professional memory of Reiter and others like him within our medical culture except as a symbol of what our societal values obligate us to reject. We suggest reverting to or substituting other terms for the syndrome (such as spondyloarthropathy, spondyloarthritis, oligoarthritis, inflammatory oligoarthritis, reactive arthritis, [oligo-] arthritis with conjunctivitis/urethritis/diarrhea, etc) until pathophysiologic or other insights lead to better ones. (It should be noted that the description of this syndrome was not original to Reiter and that current nomenclature is probably in need of revision in any case because the terminology and classification is outdated and clinically imprecise.) We offer these recommendations because we cannot forget. We cannot forget that Reiter and others like him represented an abhorrent evil. We cannot forget that Reiter and others like him desecrated the traditions of our civilization. We cannot forget that Reiter and

  7. Organisationsaspekter på Hans Persson Bil

    OpenAIRE

    Georgenson, Tom; Henriksson, Anders

    2007-01-01

    Vår hypotes är det finns ett särskilt sätt att arbeta på eller att det finns en anda inom koncernen och bland medarbetare. När nu ett utomstående företag som dessutom varit bitter konkurrent under många år tar över syret tror vi det finns en risk att en sådan anda kan kvävas eller att sättet att arbeta förändras. Syftet med vår studie är att genom en fallstudie undersöka hur maktstrukturen ser ut inom Hans Persson bil i Västerås, med ett fokus på beslutsfattande. Vi vill också undersöka om an...

  8. Problemática sobre la disponibilidad de los Bienes Jurídicos Individuales y Responsabilidades Emergentes

    OpenAIRE

    Ignacio Curbelo Solari

    2013-01-01

    Sobre el concepto de Disponibilidad. Concepto de Bien Jurídico y sus funciones. El Consentimiento. Breve Historia. Bienes Jurídicos Colectivos e Individuales. Naturaleza Jurídica del Consentimiento. Posición de Jescheck, Roxin y Muñoz Conde. Posición de los principales autores nacionales: Prof. Gonzalo Fernández, Miguel Langón, Germán Aller, Pedro Montano. Los requisitos del consentimiento. En la doctrina extranjeraEn la doctrina uruguaya El consentimiento presunto. Requisitos del consentimie...

  9. "Cooperativismo y economía del bien común" (Cooperativism and economy of the common good)

    OpenAIRE

    Alejandro Martínez Charterina

    2013-01-01

    En los últimos años (desde 2010) se está promocionando elmodelo de economía del bien común que muestra un buen número de cooperativascomo ejemplo de lo que promociona en el orden empresarial. Este trabajotrata de destacar el interés de las cooperativas por la mejora social, en general,y en particular en el medio en el que se hacen presentes, trascendiendolos intereses de cada cooperativa singular. Esto queda bien unido a las pretensionesde la Alianza Cooperativa Internacional dirigidas a la p...

  10. Programas políticos y bienes y usos comunales en Lorena durante la Revolución Francesa

    OpenAIRE

    Ríos, Manuel

    2015-01-01

    La historiografía inglesa ha ahondado en el estudio de los bienes y usos comunales con el propósito de comprender el rol que jugó la transformación de los mismos en la transición del feudalismo al capitalismo. No obstante, su contraparte francesa ha tendido a relegar este tipo de estudios a un segundo plano, sobre todo en lo que a los usos comunales respecta. De hecho, en los últimos veinte años se ha postulado la necesidad de estudiar a los bienes y usos comunales por separado, compartimenta...

  11. Brad Mehldau : Analytiske perspektiver på hans spillestil

    OpenAIRE

    2012-01-01

    Brad Mehldau (f. 1970) må kunne sies å være en av de store nålevende jazzpianistene, og han har gjort seg vel bemerket i både hans hjemland USA og internasjonalt. Han har samarbeidet med kjente utøvere som Pat Metheny, Joshua Redman, Kurt Rosenwinkel, Charlie Haden, Lee Konitz, etc. I sin egen trio, med bassist Larry Grenadier og trommeslager Jeff Ballard, spiller Mehldau en blanding av jazzstandardlåter, egne komposisjoner og poplåter i hans egne arrangementer. Denne oppgaven er sentrert run...

  12. El emprendimiento y el bien común: ¿competencias complementarias o excluyentes?

    Directory of Open Access Journals (Sweden)

    Juan David Enciso-Congote

    2010-04-01

    Full Text Available Este trabajo propone un análisis comparativo entre los requerimientos de la formación de competencias para el emprendimiento y para el desempeño laboral, de acuerdo con el escenario que sirve de contexto a cada una de ellas. En el caso del desempeño laboral, se toma como punto de referencia la estructura burocrática descrita por Max Weber. En cuanto al emprendimiento, las raíces son antropológicas, la naturaleza humana, independientemente de cualquier referente cultural o histórico. Estas consideraciones proporcionan un marco de referencia para reflexionar sobre las dificultades conceptuales y pedagógicas que obstaculizan la construcción de una visión más inclusiva de lo público y del compromiso que debe tener un profesional con la búsqueda del bien común y, por tanto, de la responsabilidad que recae en la formación universitaria para procurar este cometido.

  13. De las cenizas a la Red: el Periodismo como bien común

    Directory of Open Access Journals (Sweden)

    José Carlos Sendín Gutiérrez

    2014-11-01

    Full Text Available Sampedro nos ofrece y comparte –porque el libro se puede leer en partes también en la red– no sólo y fundamentalmente un alegato a favor del periodismo, sino además, una defensa de un nuevo poder ciudadano y de una nueva democracia. Desde las primeras líneas el lector se siente sacudido por el alto voltaje de los datos, los personajes y el análisis perspicaz de la transformación social que parece apuntarse, pero que hasta ahora nadie había sabido traducir en palabras. Palabras que a veces parecen querer levantar por las solapas al que lee, como diciendo, “entérate, está pasando ahora y es importante que lo descubras”, mientras desarrolla ideas a las que vuelve y recalca, pasados los capítulos, en un ejercicio circular que pretende dejar clara –y lo consigue– la tesis central: ya existe una nueva forma de periodismo entendido como bien común (sí, al igual que el agua o el aire que respiramos, libre, de código abierto y mancomunado. Aire nuevo para una sociedad desencantada, para un periodismo en busca de modelos y para unas aulas donde se forman los futuros profesionales en una universidad maltratada, pero quizá por ello, también sumida en la conformidad de un saber rutinario.

  14. Comunicación política y bien común en tiempo de elecciones

    OpenAIRE

    Pérez-Latre, F.J. (Francisco Javier)

    2015-01-01

    Para que la política funcione es necesaria una comunidad de personas diversas, pero que sienten respeto y admiración mutua y coinciden en el afán de mejorar la sociedad y trabajar por el bien común.

  15. TTIP: Análisis jurídico-técnico y su impacto en el comercio de bienes

    OpenAIRE

    Aizpiri Oliván, Martín

    2016-01-01

    El TFG en cuestión trata de abordar desde una perspectiva técnico-jurídica los elementos y procedimientos para liberalizar el comercio que se plantean en el TTIP, con especial mención al comercio de bienes.

  16. Obituary: Hans Albrecht Bethe, 1906-2005

    Science.gov (United States)

    Wijers, Ralph

    2007-12-01

    One of the unquestioned giants of physics and astrophysics, Hans Bethe, died on 6 March 2005, at the venerable age of 98, in his home town of Ithaca, New York. Seven decades of contributing to research and a Nobel Prize for his work on stellar hydrogen burning make a listing of his honors superfluous (besides being impossible in this space). Bethe was born in Strassburg, in then German Alsass Lothringen, on 2 July 1906. His father, Albrecht Julius Bethe (1872-1954), taught physiology at the University, and his mother, Anna Kuhn (1876-1966), was a musician and writer. Both his grandfathers were physicians. He spent his youth in Strassburg, Kiel, and Frankfurt, and some time in sanatoria due to tuberculosis. Hans's first scientific paper, at age 18, was with his father and a colleague, on dialysis. His education and early career in Germany brought him into contact with many top stars in the quantum revolution. Starting in Frankfurt in chemistry, Bethe soon switched to physics, taught there by Walter Gerlach and Karl Meissner, among others. In 1926, he successfully applied to join Arnold Sommerfeld's group in Munich, where he met one of his later long-term collaborators, Rudolf Peierls. Bethe considered his entry into physics to have come at an ideal time, with the new ideas of wave mechanics being developed and discussed right there; it was certainly also at an ideal place. His doctoral thesis was on the theory of electron diffraction by crystals, following the experimental work by Clinton Davisson and Lester Germer and the work on X-ray diffraction by Max von Laue and Paul Ewald. The newly minted doctor went from there briefly to Frankfurt and then to Ewald in Stuttgart, where he felt at home academically and personally. In 1939, Bethe would marry Ewald's daughter Rose. Not much later, though, Sommerfeld recalled him to Munich, where Sommerfeld created a Privatdozent position for him. There he worked out the solution for a linear chain of coupled spins by what we

  17. In memoriam : Dr. J. (Hans) van den Assem

    NARCIS (Netherlands)

    Beukeboom, Leo; Werren, John (Jack)

    2014-01-01

    On 11 April 2014 behavioral biologist Hans van den Assem passed away. As member of the Ethology group at the University of Leiden he has contributed significantly to the blossoming of the field of behavioral biology. Hans was a pioneer in the study of mating behavior of parasitoid wasps, contributed

  18. Hans Henriksen Ussing. 30 December 1911 - 22 December 2000

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid

    2009-01-01

    Hans Ussing was born on 30 December 1911 at Sorø Academy in Denmark, where his father Dr Henrik Ussing was a lecturer and, as historian, a leading Danish folklorist. After his doctoral thesis in marine biology, Hans Ussing came to August Krogh's laboratory, where he studied protein turnover by...

  19. Hans Kelsen: pensador político

    Directory of Open Access Journals (Sweden)

    Sara Lagi

    2011-01-01

    Full Text Available Hasta la publicación de Sobre la esencia y el valor de la democracia, Hans Kelsen era solo conocido como experto en derecho público. El valor de este artículo de Lagi radica en rescatar de la obra kelseniana un aspecto casi por completo olvidado por la crítica, a saber, sus análisis sobre el significado y las características de la democracia parlamentaria en los Estados modernos. Se aborda la cuestión no solo desde el debate teórico sino también desde su contexto histórico¿político. La teoría política de Kelsen es considerada una parte integral de su doctrina central, presentada en Teoría pura del derecho, su obra más conspicua. Un análisis del trabajo sobre la esencia y el valor de la democracia nos restituye la imagen de un Kelsen como original pensador político. Se analizan las dos ediciones de Sobre la esencia y el valor de la democracia (1920¿1929 con estos propósitos: comprender por qué decidió dedicarse a la teoría de la democracia un teórico que rigurosamente defendió la separación de la esfera jurídica respecto de la historia, la filosofía y la política; y por qué no se limitó a explicar la esencia de la democracia sino que decidió concentrarse en clarificar qué se entiende por valor de la democracia.

  20. Marketing Ético como Fundamento del Bien Común en Organizaciones Humanas

    Directory of Open Access Journals (Sweden)

    Alejandro Fernández Baptista

    2014-01-01

    Full Text Available Los hombres poseen necesidades que deben ser satisfechas con el objeto de lograr una vida cónsona con los principios básicos de dignificación de la persona humana, alimento, vestido, medicamentos, comunicación, entretenimiento, transporte, entre otras, son algunas de las necesidades básicas que los seres humanos día tras día se esfuerzan por cubrir mediante el trabajo digno, utilizando para ello las potencialidades propias de cada quien. Las organizaciones modernas por medio del marketing como proceso administrativo, pretende lograr la satisfacción de tales necesidades por medio de la identificación oportuna de dichos requerimientos, elaborando productos y servicios que los satisfagan al crear una propuesta de valor superior a tales expectativas. Sin embargo, tal propuesta debería estar inmersa dentro de parámetros éticos y morales, las cuales garanticen la correcta utilización de cada uno de los elementos de la mezcla de mercadotecnia, producto, precio, promoción y la distribución. De esta manera los gerentes de marketing al momento de tomar decisiones éticas sobre estos tópicos, permitirían en desarrollo de organizaciones humanas promotoras del bien común dentro del contexto donde se desenvuelvanPalabras Clave: Marketing ético; Bien Común; Organizaciones Humanas. Marketing Ethical as the Foundation of the Common Wealth on Human OrganizationsAbstractThe people have needs that must be met for a life in keeping with the basic principles of dignification of the human person, food, clothing, medicines, communication, entertainment, transportation, among others, are some of the basic needs of human beings every day strive to cover using decent, using work of their own potential each person. Modern organizations marketing as administrative process aims at achieving the satisfaction of those needs in the timely identification of those requirements, developing products and services satisfying them to create a proposal for a value

  1. Bienes rústicos de aprovechamiento público en la Valencia moderna

    Directory of Open Access Journals (Sweden)

    David BERNABÉ GIL

    2009-12-01

    Full Text Available RESUMEN: Analiza el presente trabajo diversos aspectos relacionados con los derechos de aprovechamiento público que confluían en los espacios rústicos no cultivados del antiguo Reino de Valencia, así como la naturaleza de los problemas que solía suscitar su atribución dominical, dada la frecuente superposición de instancias institucionales con pretensiones de control. A partir de la compleja tipología que la casuística al respecto —aún escasa y mal conocida— permite entrever, queda en evidencia el fuerte arraigo de los elementos de regulación municipal vigentes en el realengo, si bien en franco retroceso ante los tardíos intentos de control por el Real Patrimonio. En los señoríos, sin embargo, son los derechos del titular de la jurisdicción los que consiguen prevalecer, aunque no necesariamente por exclusión de los reconocidos a la comunidad.ABSTRACT: This study analyzes different aspects related to the rights of public usage with regard to uncultivated agricultural spaces in the ancient Kingdom of Valencia, as well as the nature of the problems normally arising from the conferring of their feudal status, due to the frequent superimposing of institutional requests to gain control. With regard to the complex typology that the corresponding casuistry (still scarce and hardly known suggests, we can highlight the fact that the elements of municipal regulation that existed within the state were well-established, although they were clearly in decline in the face of the Royal Trust's late attempts to gain control. However, as regards the estates, the ownership rights of the jurisdiction were the ones that finally prevailed, although not necessarily by excluding the rights of the community.

  2. La Salud en Colombia: ¿Qué tan meritorio y público es este bien o servicio?

    Directory of Open Access Journals (Sweden)

    Carlos Arturo Meza Carvajalino

    2003-11-01

    Full Text Available La controversia en la prestación del servicio de salud en Colombia se plantea desde distintos ámbitos, tanto en las instituciones del Estado como en la esfera académica, situación que afecta el desarrollo de la política del sector de la salud, por encontrarse este servicio asociado y vinculado con los derechos económicos, sociales y culturales. Además por el desconocimiento del principio que en esencia le define como un bien que, por sus características, es meritorio. Lamentablemente, en la práctica se convierte en un bien público preferente.

  3. EL DILEMA DE LA CONTRIBUCIÓN VOLUNTARIA A BIENES PÚBLICOS: UNA REVISIÓN DE TRABAJOS EXPERIMENTALES

    Directory of Open Access Journals (Sweden)

    Luis Alejandro Palacio García

    2014-01-01

    Full Text Available El artículo presenta una revisión de los experimentos realizados sobre bienes públicos apoyados en el mecanismo de contribución voluntaria. La evidencia empírica existente muestra que los individuos no son solo los seres egoístas y competitivos que supone la teoría económica ortodoxa, sino que también son seres bondadosos y altruistas. Aunque los diversos trabajos experimentales concuerdan en la existencia de estos sentimientos catalogados como "bondad", no es claro si los sujetos actúan así para mejorar el bienestar de los demás (altruismo o porque se sienten bien realizando este tipo acciones (satisfacción moral.

  4. Bien commun, conflits d’intérêts et délibération éthique

    OpenAIRE

    Müller, Denis

    2016-01-01

    Si la notion de bien commun paraît de prime abord trop ambitieuse, trompeuse en ses promesses excessives et inaccessibles, elle est néanmoins nécessaire au débat éthique dans l’espace public contemporain. Cette contribution veut montrer comment une compréhension critique de la notion controversée de bien commun peut s’avérer compatible avec une prise en compte réaliste et responsable des conflits d’intérêts et de la délibération éthique. L’exemple du débat français sur la laïcité permet à cet...

  5. Recensión La economía del bien común, de Christian Felber

    Directory of Open Access Journals (Sweden)

    Antonio Fernández Laborda

    2014-03-01

    Full Text Available El autor propone que el sistema económico persiga el mismo fin que el establecido en las normas políticas, es decir, el bien común. Felber parte de la premisa de que las empresas compiten entre ellas y, principalmente, se preocupan por aumentar sus beneficios en su cuenta de resultados. Por ello propone que esos resultados incorporen índices relacionados con valores como el respeto a los derechos humanos, a los derechos de los trabajadores, al medio ambiente y a los valores democráticos como la cooperación entre empresas  que decide practicar esa misma entidad. Toda esta serie de nuevos índices formarían también parte del balance del bien común

  6. "Cooperativismo y economía del bien común" (Cooperativism and economy of the common good

    Directory of Open Access Journals (Sweden)

    Alejandro Martínez Charterina

    2013-01-01

    Full Text Available En los últimos años (desde 2010 se está promocionando elmodelo de economía del bien común que muestra un buen número de cooperativascomo ejemplo de lo que promociona en el orden empresarial. Este trabajotrata de destacar el interés de las cooperativas por la mejora social, en general,y en particular en el medio en el que se hacen presentes, trascendiendolos intereses de cada cooperativa singular. Esto queda bien unido a las pretensionesde la Alianza Cooperativa Internacional dirigidas a la promoción de conductasque puedan llevar a un cambio social y una economía sostenible, quereconocemos como las aspiraciones de conquista del cooperativismo.

  7. Problemática sobre la disponibilidad de los Bienes Jurídicos Individuales y Responsabilidades Emergentes

    Directory of Open Access Journals (Sweden)

    Ignacio Curbelo Solari

    2013-12-01

    Full Text Available Sobre el concepto de Disponibilidad. Concepto de Bien Jurídico y sus funciones. El Consentimiento. Breve Historia. Bienes Jurídicos Colectivos e Individuales. Naturaleza Jurídica del Consentimiento. Posición de Jescheck, Roxin y Muñoz Conde. Posición de los principales autores nacionales: Prof. Gonzalo Fernández, Miguel Langón, Germán Aller, Pedro Montano. Los requisitos del consentimiento. En la doctrina extranjeraEn la doctrina uruguaya El consentimiento presunto. Requisitos del consentimiento presunto.Relevancia del consentimiento en el Derecho Positivo. Derecho extranjero Derecho Uruguayo. Diversas situaciones. El art. 44 del CP. La Vida. El consentimiento y la responsabilidad de los médicos. Las intervenciones transexuales. La Eutanasia La ley 18.473 de Voluntad anticipada. La auto puesta en peligro.

  8. Method for Observing Intravascular BongHan Duct

    CERN Document Server

    Jiang, X; Shin, H; Lee, B; Choi, C; Soh, K; Cheun, B; Baik, K; Soh, K; Jiang, Xiaowen; Kim, Hee-kyeong; Shin, Hak-soo; Lee, Byong-chon; Choi, Chunho; Soh, Kyung-soon; Cheun, Byeung-soo; Baik, Ku-youn; Soh, Kwang-sup

    2002-01-01

    A method for observing intra blood vessel ducts which are threadlike bundle of tubules which form a part of the BongHan duct system. By injecting 10% dextrose solution at a vena femoralis one makes the intravascular BongHan duct thicker and stronger to be easily detectable after incision of vessels. The duct is semi-transparent, soft and elastic, and composed of smaller tubules whose diameters are of 10$\\mu$m order, which is in agreement with BongHan theory.

  9. Evaluación de riesgos en el sector de fabricación de bienes de equipo

    OpenAIRE

    González Antuña, Pablo

    2013-01-01

    El propósito fundamental de este trabajo es orientar a todo el personal que trabaja en el sector de fabricación de bienes de equipo, sobre las condiciones de trabajo, las condiciones de las instalaciones a través de una evaluación de riesgos laborales presentes en las áreas de trabajo de dicho sector y sobre las medidas preventivas a adoptar para controlar el riesgo laboral

  10. Predictors for dioxin accumulation in residents living in Da Nang and Bien Hoa, Vietnam, many years after Agent Orange use.

    Science.gov (United States)

    Pham, Diem T; Nguyen, Hang M; Boivin, Thomas G; Zajacova, Anna; Huzurbazar, Snehalata V; Bergman, Harold L

    2015-01-01

    Agent Orange (AO) was the main defoliant used by the US in Vietnam from 1961 to 1971; AO was contaminated with dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, or TCDD). Three major dioxin “hot spots” remain from previous AO storage and use at former US bases at Bien Hoa, Da Nang, and Phu Cat, posing potential health risks for Vietnamese living on or near these hot spots. We evaluated potential risk factors contributing to serum TCDD levels in Vietnamese residents at and near contaminated sites in Da Nang and Bien Hoa, Vietnam. We used multiple linear regression to analyze possible associations of blood dioxin concentrations with demographic, socioeconomic, lifestyle, and dietary risk factors for residents living on or near these hot spots. For the Da Nang study, fish farming on the site, living on property flooded from monsoon rains, and age were among the factors showing significant positive associations with serum TCDD concentrations. For the Bien Hoa study, fish farmers working at this site and their immediate family members had significantly higher serum TCDD concentrations. Our results suggest that water-related activities, especially fish-farming, at the hot spots increased the risk of exposure to dioxin. PMID:25463251

  11. han /Smoke in the Context Verse 10 of Sura ad - Duk han

    Directory of Open Access Journals (Sweden)

    Gökhan ATMACA

    2015-07-01

    Full Text Available Holy Qur’an is the last book was sent to mankind as guidance. Prophet has notified the Qur’an. This is because the task for him. He also explained the Qur’an. Companions of the Prophet are appealed to the Prophet when they do not understand the issue. After the Prophet’s death continued activities to understand the Qur’an. For this reason, efforts have been made to understand the Qur’an. It is also written with commentary that explains the verse. There are various opinions on the books of taf sir about the meaning of the verse. Each commentators have described the verse based on their knowledge and understanding. They were found in the preferences among the various opinions. Mufessir sometimes unanimously agreed on the meaning of the verse. Som etimes opinions are different. One of the verse is that the variety of opinions about the 10th verse of Surah ad - Dukhan. Translation of the verse is: “ Then watch thou for the Day that the sky will bring forth a kind of smoke (or mist/ Dûhan plainly visible . ” There are various opinions about what the words mean the smoke/ Dûhan . There are still various views on this incident when or where when. There are several proofs for each view. There are three views about the smoke. According to the first view is from the stink of smoke signals. Therefore, this event has not yet occurred. According to the second opinion. The Prophet prayed against Meccan unbelievers. There famine occurred. As a result, they were subjected to fasting. They start seeing smoke because of h unger. According to a third opinions. Smoke appeared on the day of the conquest of Mecca. Because that day a rising dust set, and covered the sky in the form of smoke .

  12. Estlandse uithaal naar oud-ambassadeur / Hans Jacobs

    Index Scriptorium Estoniae

    Jacobs, Hans

    2008-01-01

    Hollandi ajakirjanikud küsisid president Toomas Hendrik Ilveselt arvamust endise Hollandi suursaadiku Hans Glaubitzi tagakiusamise kohta. Eestis visiidil olnud Hollandi kuninganna Beatrix'i ja president Toomas Hendrik Ilvese kohtumisest

  13. On Professor HAN Bi-ying's Academic Experience

    Institute of Scientific and Technical Information of China (English)

    赵杰

    2006-01-01

    @@ Professor HAN Bi-ying is a chief doctor in the acupuncture department of Guang An Men Hospital of China Academy of Chinese Medical Science. She has been engaged in clinical practice for nearly 40 years and accumulated abundant clinical experience, especially in clinical syndrome differentiation. I am fortunate to follow professor HAN to practice acupuncture on weekends and learn from him. I now present her academic thoughts and clinical experience with proven cases for References.

  14. Children and Moods in Hans Christian Andersen's Travel Books

    DEFF Research Database (Denmark)

    Jensen, Lars Bo

    2008-01-01

    A categorization of moods, atmospheres and motifs connected with the children in Hans Christian Andersen’s five travel books (1831-1868). Surprisingly, death and darkness and, on the other side, eroticism and (red) light are the dominant two categories.......A categorization of moods, atmospheres and motifs connected with the children in Hans Christian Andersen’s five travel books (1831-1868). Surprisingly, death and darkness and, on the other side, eroticism and (red) light are the dominant two categories....

  15. Analysis of paleomagnetic data: a tribute to Hans Zijderveld. Introduction

    OpenAIRE

    Dekkers, M.J.; Langereis, C. G.; Voo, R. van der

    1997-01-01

    This special issue of ‘Geologie en Mijnbouw’ is dedicated to Professor Hans Zijderveld, head of the paleomagnetic laboratory ‘Fort Hoofddijk’ of Utrecht University until March 1995. Hans was among the founders of this laboratory and he guided the paleomagnetic group at Utrecht throughout his career. The value of his many contributions to the field of paleomagnetism are best seen in the perspective of the development of paleomagnetism, which will be presented first.

  16. Personality: two ways of thinking about it. Hans Eysenck Lecture

    OpenAIRE

    Davies, Martin F.

    2004-01-01

    In his Hans Eysenck Lecture, Martin Davies describes how he has continued to integrate the correlational and experimental in the study of personality and cognition. Introduction: HANS Eysenck was one of the first people to combine what Cronbach (1957) called the two disciplines of scientific psychology – the correlational and the experimental. In this article I’ll describe my own correlational and experimental research into the role of confirmatory processing in personality questionnaire...

  17. Ischemic stroke susceptibility gene in a Northern Han Chinese population

    OpenAIRE

    Wang, Haiping; Shi, Shujuan; Yan, Wenjing; Song, Yan; Zhan, Jingjing; Zhang, Chen; Wang, Haiji

    2013-01-01

    Interleukin-18 gene promoter polymorphisms are potential risk factors for ischemic cerebrovascular disease, and the –607C allele may increase ischemic stroke risk in the Han Chinese population. In the present study, we recruited 291 patients with ischemic cerebrovascular disease from the Affiliated Hospital of Qingdao University Medical College, China, and 226 healthy controls. Both patients and controls were from the Han population in northern China. Immunoresonance scattering assays detecte...

  18. Home Energy Management System Using NILM, Low-Cost HAN

    Institute of Scientific and Technical Information of China (English)

    Qasim Khalid; Naveed Arshad; Nasir Khan; Taha Hassan; Fahad Javed; Jahangir Ikram

    2014-01-01

    Home energy management systems (HEMs) are used to provide comfortable life for consumers as well as to save energy. An essential component of HEMs is a home area network (HAN) that is used to remotely control the electric devices at homes and buildings. Although HAN prices have dropped in recent years but they are still expensive enough to prohibit a mass scale deployments. In this paper, a very low cost alternative to the expensive HANs is presented. We have applied a combination of non-intrusive load monitoring (NILM) and very low cost one-way HAN to develop a HEM. By using NILM and machine learning algorithms we find the status of devices and their energy consumption from a central meter and communicate with devices through the one-way HAN. The evaluations show that the proposed machine learning algorithm for NILM achieves up to 99%accuracy in certain cases. On the other hand our radio frequency (RF)-based one-way HAN achieves a range of 80 feet in all settings.

  19. Economía, bienes públicos puros e Internet : revelando el caso del FLOSS (“Free/Libre Open Source Software” o “Software Libre y Software de Código Abierto”)

    OpenAIRE

    Soler Muñoz, Rafael

    2013-01-01

    Desde que Paul Samuelson publicase en 1954 su obra “The pure theory of public expenditure”, diferenciando los bienes económicos entre bienes públicos y bienes privados, ha existido controversia sobre la posibilidad de que los bienes públicos pudiesen encontrarse en estado "puro". En nuestra tesis exponemos, con el ejemplo del FLOSS (Free/Libre Open Source Software), como la existencia de bienes públicos puros tendría lugar cuando bienes digitales son distribuidos a través de redes "peer to pe...

  20. Postoperative comparison of result of renal transplantation between ethnic minorities and Han recipients after receiving kidneys from Han donors

    Directory of Open Access Journals (Sweden)

    Han-wen CUI

    2013-04-01

    Full Text Available Objective  To analyze the outcomes and postoperative complications of renal transplant recipients of ethnic minorities and Han population in China, and investigate the differences between them. Methods  Clinical data from 89 minorit y patients and 100 Han patients who had received renal transplant of Hans' donators in Organ Transplantation Center of PLA from 1990 to 2012 were retrospectively analyzed. The general data before transplantation, and rate of short-term survival of the graft, incidence of delayed graft function (DGF, acute rejection, and pulmonary infection after transplantation were analyzed and compared. Results  No statistical difference was found in the preoperative personal profile between the recipients of minorities and Han nationality. In the recipients of minorities and Han nationality, the 1-year graft survival rate was 89.9% and 92%, the respective incidence of DGF was 28.1% and 27.0%, and the respective incidence of acute rejection was 22.5% and 19.0%, and there was no significant difference between them (P>0.05. The incidence of pulmonary infection was higher in minority recipients (30.3% than in Han recipients (10.0%, P0.05. Conclusion  The short-term clinical outcome of renal transplant recipients seems to be similar in different Chinese ethnic groups, but the incidence of pulmonary infection is higher in minority recipients, so it is important to strengthen monitoring in early postoperative period.

  1. Comment on "Radiocarbon Calibration Curve Spanning 0 to 50,000 Years B.P. Based on Paired 230Th/234U/238U and 14C Dates on Pristine Corals" by R.G. Fairbanks, R. A. Mortlock, T.-C. Chiu, L. Cao, A. Kaplan, T. P. Guilderson, T. W. Fairbanks, A. L. Bloom, P

    Energy Technology Data Exchange (ETDEWEB)

    Reimer, P J; Baillie, M L; Bard, E; Beck, J W; Blackwell, P G; Buck, C E; Burr, G S; Edwards, R L; Friedrich, M; Guilderson, T P; Hogg, A G; Hughen, K A; Kromer, B; McCormac, G; Manning, S; Reimer, R W; Southon, J R; Stuiver, M; der Plicht, J v; Weyhenmeyer, C E

    2005-10-02

    Radiocarbon calibration curves are essential for converting radiocarbon dated chronologies to the calendar timescale. Prior to the 1980's numerous differently derived calibration curves based on radiocarbon ages of known age material were in use, resulting in ''apples and oranges'' comparisons between various records (Klein et al., 1982), further complicated by until then unappreciated inter-laboratory variations (International Study Group, 1982). The solution was to produce an internationally-agreed calibration curve based on carefully screened data with updates at 4-6 year intervals (Klein et al., 1982; Stuiver and Reimer, 1986; Stuiver and Reimer, 1993; Stuiver et al., 1998). The IntCal working group has continued this tradition with the active participation of researchers who produced the records that were considered for incorporation into the current, internationally-ratified calibration curves, IntCal04, SHCal04, and Marine04, for Northern Hemisphere terrestrial, Southern Hemisphere terrestrial, and marine samples, respectively (Reimer et al., 2004; Hughen et al., 2004; McCormac et al., 2004). Fairbanks et al. (2005), accompanied by a more technical paper, Chiu et al. (2005), and an introductory comment, Adkins (2005), recently published a ''calibration curve spanning 0-50,000 years''. Fairbanks et al. (2005) and Chiu et al. (2005) have made a significant contribution to the database on which the IntCal04 and Marine04 calibration curves are based. These authors have now taken the further step to derive their own radiocarbon calibration extending to 50,000 cal BP, which they claim is superior to that generated by the IntCal working group. In their papers, these authors are strongly critical of the IntCal calibration efforts for what they claim to be inadequate screening and sample pretreatment methods. While these criticisms may ultimately be helpful in identifying a better set of protocols, we feel that there are

  2. Perspectivas sobre la gobernanza de los bienes y la ciudadanía en la obra de Elinor Ostrom

    OpenAIRE

    Leticia Merino Pérez

    2014-01-01

    Este trabajo reflexiona sobre las principales aportaciones conceptuales y me - todológicas de la obra de Elinor Ostrom, con - siderando el contexto conceptual y político en que emergió y se desarrolló: la polémica con las hegemónicas tesis de Garret Hardin sobre la tragedia de los bienes comunes y la teo - ría de la elección racional. Analiza las ruptu - ras y continuidades de la obra de Ostrom en relación con distintos paradigmas dominantes en las ciencias sociales. Indica también que sus ap...

  3. La place de l’évaluation des biens environnementaux dans la décision publique

    OpenAIRE

    Point, Patrick

    2007-01-01

    Dans les économies d’aujourd’hui, la plupart des biens et des services se voient dotés d’un prix. Ce prix agit comme un signal permettant d’orienter et de coordonner les comportements des consommateurs et des producteurs. Les ressources naturelles qui sont des dons de nature n’ont pas, pour nombre d’entre elles, un repère de prix qui leur soit attaché. Ceci crée une responsabilité spéciale pour les pouvoirs publics. Il est en effet nécessaire d’identifier les services rendus par les actifs na...

  4. Recensión La economía del bien común, de Christian Felber

    OpenAIRE

    Antonio Fernández Laborda

    2014-01-01

    El autor propone que el sistema económico persiga el mismo fin que el establecido en las normas políticas, es decir, el bien común. Felber parte de la premisa de que las empresas compiten entre ellas y, principalmente, se preocupan por aumentar sus beneficios en su cuenta de resultados. Por ello propone que esos resultados incorporen índices relacionados con valores como el respeto a los derechos humanos, a los derechos de los trabajadores, al medio ambiente y a los valores democráticos como ...

  5. La gestión de lo común y para el bien común desde las aulas

    OpenAIRE

    Ortiz García, Mercedes; Garay Montañez, Nilda; Gómez Calvo, Verónica; Hidalgo Moratal, Moisés; Carmen PASTOR SEMPERE; Romero-Tarín, Adela

    2014-01-01

    La enseñanza universitaria fruto de la investigación del profesorado, enriquecida con la participación del alumnado, debe servir para realizar una reflexión de cuánto acontece fuera y dentro de las Aulas, para que los alumnos crezcan como expertos profesionales pero también como ciudadanos comprometidos con el servicio al bien común desde el saber y la ética. De ahí que nuestra Red a través de sus distintas disciplinas (Derecho Constitucional, Derecho Administrativo, Ciencia política y de la ...

  6. El emprendimiento social como impulsor del cambio hacia la economía del bien común

    OpenAIRE

    Priede Bergamini, Tiziana; López-Cózar Navarro, Cristina; Platero Jaime, Manuel; Arco Juan, Francisco Javier del; Díaz Ridao, Pedro

    2015-01-01

    En el presente trabajo se realiza un análisis conjunto de la Economía del Bien Común (EBC) y el emprendimiento social, con el objetivo de poner de relieve la relación existente entre ambos. Para ello, se analizan las bases sobre las que se asientan estos conceptos, y se realiza una comparación que permite establecer su conexión, destacando la importancia de elementos clave en el orden económico y en el social, tales como la búsqueda de un crecimiento equilibrado y sostenible, una creciente pr...

  7. Las madres del bien morir del Hospital de las Cinco Llagas de Sevilla en el Antiguo Régimen

    OpenAIRE

    Rivasplata Varillas, Paula Ermila

    2014-01-01

    Después del Concilio de Trento, el morir y el purgatorio cobraron gran importancia en la vida de los católicos. En instituciones regidas por la Iglesia como el hospital de las Cinco Llagas de Sevilla surgieron otras personas que ayudaban a los curas a bien morir. Se trataba de la “madre agonizante” que se encargaba de ayudar a las moribundas a morir en paz que ejecutaba desde que el médico o cirujano ordenaba administrar el Santo Óleo de la extremaunción. Esta...

  8. Management of radioactive waste at Novi Han Repository

    International Nuclear Information System (INIS)

    The Novi Han Repository is the only existing repository in Bulgaria for the disposal of radioactive waste from nuclear applications in industry, medicine and research. The repository was constructed in the early sixties according to the existing requirements. It was operated by the Institute for Nuclear Research and Nuclear Energy for more than thirty years without any accident or release of radioactivity to the environment, but without any investment for upgrading. As a consequence, the Bulgarian Nuclear Safety Authority temporarily stopped the operation of the repository in 1994. The measures for upgrading the Novi Han Repository, supported by the IAEA under TC Project BUL/4/005 'Increasing Safety of Novi Han Repository', are presented in this paper. They comprise: assessment of radionuclide inventory and future waste arisings, characterisation of disposal vaults, characterisation of the site, safety assessment, upgrading of the monitoring system, option study for the selection of treatment and conditioning processes and the development of a conceptual design for low and intermediate level waste processing and storage facility, immediate measures for improvement of the existing disposal vaults and infrastructure, construction of above-ground temporary storage structures, and resuming the operation of the Novi Han Repository. The necessary activities for re-licensing of the Novi Han Repository, construction of a waste processing and storage facility and a disposal facility for spent sealed sources are discussed. (author)

  9. Thermoluminescence authentication of T`ang and Han Dynasty pottery

    Energy Technology Data Exchange (ETDEWEB)

    Price, D.M. [Wollongong Univ., NSW (Australia). School of Geosciences

    1997-12-31

    More than 80 pieces of T`ang Dynasty and 40 Han Dynasty style ceramic wares have been analysed to determine the amount of thermoluminescence (TL) accumulated since the initial firing of the object and the level of the radiation flux which has created the TL. This paper presents a summary of the thermoluminescence analysis results. Approximately 60% of Han ceramics and 45% of the T`ang pottery authenticated have been shown to belong to periods other than that stylistically suggested. Items which have been found not to be of the anticipated antiquity generally fall into distinct age groups. Of the T`ang wares the most commonly copied item is found to be the horse and for the Han pieces, human figures and ewers/pots/vases represent the most frequently reproduced wares.

  10. Thermoluminescence authentication of T'ang and Han Dynasty pottery

    International Nuclear Information System (INIS)

    More than 80 pieces of T'ang Dynasty and 40 Han Dynasty style ceramic wares have been analysed to determine the amount of thermoluminescence (TL) accumulated since the initial firing of the object and the level of the radiation flux which has created the TL. This paper presents a summary of the thermoluminescence analysis results. Approximately 60% of Han ceramics and 45% of the T'ang pottery authenticated have been shown to belong to periods other than that stylistically suggested. Items which have been found not to be of the anticipated antiquity generally fall into distinct age groups. Of the T'ang wares the most commonly copied item is found to be the horse and for the Han pieces, human figures and ewers/pots/vases represent the most frequently reproduced wares

  11. El fondo documental audiovisual de Radiotelevisión Valenciana: Evolución, transformación y Bien de Interés Cultural. Patrimonio Audiovisual de la Comunidad Valenciana

    Directory of Open Access Journals (Sweden)

    Alfonso-Noguerón, Lola

    2014-07-01

    Full Text Available El Col·legi Oficial de Bibliotecaris i Documentalistes de la Comunitat Valenciana (COBDCV, junto a la Associació Ciudadana i Comunicació (ACICOM han solicitado recientemente la protección de Bien de Interés Cultural (BIC, para los fondos documentales y archivo de Radiotelevisió Valenciana SAU y Radiotelevisión Española de la Comunidad Valenciana. En este texto se analiza, la evolución y transformación de los materiales audiovisuales creados por las empresas del que fuera el Grupo de RTVV a lo largo de los veinticuatro años de emisión. Se mostrará cual ha sido la evolución de este archivo y la situación actual de los materiales, de las bases de datos y del sistema de gestión de contenidos multimedia. Se identifican las razones, como la obsolescencia de los materiales audiovisuales y la precaria situación económica del país, para evidenciar que pese a la protección legal, es un objetivo continuar con la transformación y digitalización del archivo y fondo audiovisual más importante de la Comunidad Valenciana.

  12. Hans Stimmann: 15 anni di urbanistica a Berlino

    OpenAIRE

    Bocquet, Denis

    2007-01-01

    Le titre du document édité est de la rédaction de la revue Il Giornale dell'Architettura, Janvier 2007, n.47, p. 28. Turin, Allemandi Ed. A portrait of Hans Stimmann, who has been for many years the head of the town planning bureau in the local berlin administration.Un portrait d'Hans Stimmann, urbaniste en chef de l'administration du Sénat de Berlin des années 1990 à la fin de l'année 2006.Berlin; Germany; town planning; urbanism; urbanisme; planification urbaine; urbanisme; Allemagne;...

  13. Talk about Han eaves tile art in our country

    Institute of Scientific and Technical Information of China (English)

    刘泽艺

    2015-01-01

    The Han Dynasty is the first in the history of the unified and powerful country. It is a huge momentum has also affected the development of art, especially the art of eaves tile. Pattern of Han eaves tile is the art of the Chinese nation in the classic, rich artistic value for tile study of traditional ceramic art is very necessary in China. Through the research on Eave Tile Art, can be in-jected into the power of ceramic art in China's new development.

  14. Operational safety analysis status of Novi Han repository

    International Nuclear Information System (INIS)

    This article presents the status of the safety studies and activities related to Novi Han repository. The case of this facility is such that no clear boundary exists between post-closure safety assessment and operational safety assessment. The major findings of these activities are given. The Safety Analysis Report (SAR) for Novi Han repository is developed by Risk Engineering Ltd. under a contract with the Committee on the Use of Atomic Energy for Peaceful Purposes. The general structure and main conclusions and recommendations of the SAR are presented. (author)

  15. Homage to Professor Hans-Åke Gustafsson

    CERN Multimedia

    2010-01-01

    It was with deep sadness that we learned of the death of Professor Hans-Åke Gustafsson, an internationally recognized scientist, beloved colleague and friend. He passed away on Wednesday January 13th at the Lund University Hospital, surrounded by his loved ones, after a short battle against cancer. This is a great loss for all of us in ALICE and the whole heavy ion community. Hans-Åke, Professor at Lund University, was one of the pioneers of heavy ion physics with relativistic beams since its very beginning. He started his research at CERN, as a fellow at the ISOLDE ion beam facility, and immediately after, in the early 1980 joined the Plastic Ball collaboration at the Bevalac. One of the seminal papers of the field on the discovery of collective flow in relativistic nuclear collisions, co-authored by Hans-Åke, Hans Gutbrod and colleagues, stems from this period. From that point on he was always at the forefront of research with relativistic nuclear beams, being for three de...

  16. Steve Jobs, Ameerika Hans H. Luik / Kertu Ruus

    Index Scriptorium Estoniae

    Ruus, Kertu, 1977-

    2007-01-01

    Autor võrdleb Apple'i asutajat ja juhti Steve Jobsi Eesti meediaärimehe Hans H. Luigega. Vt. samas: Jobs: ärge raisake aega teiste elu elamisele; Forbes: iPhone'ist saab Apple'i suur hitt; CV: Steven Paul Jobs. Diagramm: Apple'i aktsia

  17. Hans Christian Ørsted : natuurwetenschapper als estheticus

    NARCIS (Netherlands)

    Millekamp, Jan

    2012-01-01

    The Danish scientist Hans Christian Ørsted (1777-1851) is most famous for his discovery of electromagnetism, a discovery that literally and irreversibly changed our world. In Denmark he is also known as a poet and essayist. Interestingly, his scientific and his aesthetic work are closely interrelate

  18. [Hans Jakob Christoffel von Grimmelshausen. Saksa Simplicissimuse seiklused] / Meelis Friedenthal

    Index Scriptorium Estoniae

    Friedenthal, Meelis, 1973-

    2011-01-01

    Tutvustus: Grimmelshausen, Hans Jakob Christoffel von. Saksa Simplicissimuse seiklused, teisisõnu: ühe veidra vagabundi elulugu, kel Melchior Sternfels von Fuchshaim nimeks, et kus ja mis moel ta siia ilma sündis ning mida siin nägi, õppis, oma nahal tunda sai ja kannatas, nagu sellestki, miks ta siinsest ilmast vabatahtlikult loobub. [Tallinn] : Pegasus, c2010

  19. Aspects of Algebraic Quantum Theory: a Tribute to Hans Primas

    CERN Document Server

    Hiley, B J

    2016-01-01

    This paper outlines the common ground between the motivations lying behind Hans Primas' algebraic approach to quantum phenomena and those lying behind David Bohm's approach which led to his notion of implicate/explicate order. This connection has been made possible by the recent application of orthogonal Clifford algebraic techniques to the de Broglie-Bohm approach for relativistic systems with spin.

  20. Bohemian finds of stove tiles with the signature "HANS BERMAN"

    Czech Academy of Sciences Publication Activity Database

    Soukup, Michal B.; Soukupová, M.; Šrejber, A.

    Prague : Archaia, 2012 - (Žegklitz, J.), s. 145-164 ISBN 978-80-904408-1-4. ISSN 1805-0514. - (Studies in Post-Medieval Archaeology. 4). [Forum Archaeologiae Post-Mediaevalis. Praha (CZ), 23.03.2010-24.03.2010] Institutional research plan: CEZ:AV0Z80020508 Keywords : stove tile * Renaissance * Hans Berman Subject RIV: AC - Archeology, Anthropology, Ethnology

  1. Manipulación mediática, identidad juvenil y prostitución de un bien necesario

    OpenAIRE

    Alexander Mosquera

    2007-01-01

    Algo que identifi ca al joven de hoy es la telefonía móvil, una nueva tecnología que invade todas las esferas de lavida pública y privada, cuya presencia se hace sentir a través de una multiplicidad de “ring-tones”. Este trabajo tienecomo objetivo general describir la interrelación que se da entre la manipulación de los medios a través del discursopublicitario sobre celulares, la construcción de la identidad juvenil y la prostitución de lo que otrora fuera un bien necesariocomo el teléfono. S...

  2. La Cultura Corporativa, esencial para el desarrollo de la Economía del Bien Común

    OpenAIRE

    Guerra Carlos, Luis Enrique

    2015-01-01

    La cultura corporativa adquiere actualmente una dimensión relevante como requisito indispensable para el progreso de la Economía del Bien Común: una corriente emergente que propone un nuevo modelo económico basado en la colaboración y una redistribución más equitativa de los recursos para la búsqueda del beneficio social. La integración de esta iniciativa requiere que las compañías sean capaces de adaptar esas ideas a través de su cultura; de su manera de pensar y actuar, y de la alineación e...

  3. Étude comparative de substances bioactives pour la protection des biens patrimoniaux contre les insectes ravageurs

    OpenAIRE

    Nicosia, Grazia; Fohrer, Fabien; Dechezleprêtre, Yoanna; Billerbeck, Virginia Gisel de

    2013-01-01

    Certaines collections patrimoniales sont infestées de manière cyclique par les insectes ravageurs. Les traitements curatifs utilisés sont des opérations ponctuelles d'éradication et ne règlent en aucune manière les ré-infestations chroniques des biens culturels sensibles. Certains produits répulsifs sont pour cela utilisés de manière préventive. Or la plupart s'avèrent dangereux pour l’homme et nombre d'entre eux sont en passe d’être interdits par la réglementation européenne et sa transcript...

  4. DISEÑO DE TARIFAS DE BIENES PÚBLICOS LOCALES. CONSIDERACIONES EN TORNO AL CASO DEL AGUA POTABLE

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Gómez Prado

    2013-10-01

    Full Text Available El recurso agua se constituye como un bien de primera necesidad, que no ha sido valorado de manera adecuada. Su valor no contempla los beneficios que genera en términos de bienestar, salud, económicos y ambientales, entre otros. No se explota de manera correcta, desperdiciándolo y contaminándolo indiscriminadamente.En últimas fechas se ha acentuado la discusión sobre la problemática de la disponibilidad del agua, y aunque en algunas regiones se presenta un escenario poco pesimista, es cierto que este recurso no se utiliza adecuadamente; es decir, el problema radica en su gestión y tarifación.El presente trabajo plantea una serie de propuestas metodológicas para asignar un valor tarifario económicamente eficiente al agua potable; se determinará el precio del recurso hídrico mediante la metodología de análisis de los costos reales de producción, intentando asignar un precio que permita solventar los costos medios de producción de largo plazo, así como utilidades que permitan reinversión ante incrementos futuros de la demanda sin afectar el precio.Valga señalar que la asignación de precios al recurso hídrico no se constituye en sí misma como una finalidad; se trata, más bien de la antesala del financiamiento del desarrollo local.

  5. Transport and bioaccumulation of polychlorinated dibenzo-p-dioxins and dibenzofurans at the Bien Hoa Agent Orange hotspot in Vietnam.

    Science.gov (United States)

    Van Thuong, Nguyen; Hung, Nguyen Xuan; Mo, Nguyen Thi; Thang, Nguyen Manh; Huy, Pham Quang; Van Binh, Hoang; Nam, Vu Duc; Van Thuy, Nguyen; Son, Le Ke; Minh, Nguyen Hung

    2015-10-01

    The Bien Hoa airbase (south of Vietnam) is known as one of the Agent Orange hotspots which have been seriously contaminated by Agent Orange/dioxin during the Vietnam War. Hundreds of samples including soil, sediment and fish were collected at the Bien Hoa Agent Orange hotspot for assessment of the environmental contamination caused by dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs). The toxicity equivalency quotient (TEQ) concentration of PCDD/Fs in soil and sediment varied from 7.6 to 962,000 and 17 to 4860 pg/g dry wt, respectively, implying very high contamination of PCDD/Fs in several areas. PCDD/F levels in fish ranged between 1.8 and 288 pg/g TEQ wet wt and was generally higher than advisory guidelines for food consumption. 2,3,7,8-Tetrachlorinated dibenzo-p-dioxins (2,3,7,8-TCDD) contributed 66-99 % of TEQ for most of the samples, suggesting 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) from Agent Orange as the major source of the contamination. The vertical transport of PCDD/Fs was observed in soil column with high TEQ levels above 1000 pg/g dry wt (Vietnamese limit for necessary remediation activities- TCVN 8183:2009 (2009)) even at a depth of 1.8 m. The vertical transport of PCDD/Fs has probably mainly taken place during the "Ranch Hand" defoliant spray activities due to the leaks and spills of phenoxy herbicides and solvents. The congener patterns suggest that transports of PCDD/Fs by weathering processes have led to their redistribution in the low-land areas. Also, an estimate for the total volume of contaminated soil requiring remediation to meet Vietnamese regulatory limits is provided. PMID:25510612

  6. On the Reliability of Han Dynasty Solar Eclipse Records

    Science.gov (United States)

    Pankenier, David W.

    2012-11-01

    The veracity of early Chinese records of astronomical observations has been questioned, principally based on two early studies from the 1950s, which suggested that political motives may have led scholar-officials at court to fabricate astral omens. Here I revisit the Han Dynasty (206 BCE-220 CE) solar eclipse reports to determine whether the charge has merit for those first four centuries of the imperial period. All 127 dated solar eclipses reported in the official sources are checked for accuracy against the "Five Millennium Catalog of Solar Eclipses" produced by Espenak and Meeus (2009). The Han Dynasty records prove remarkably accurate. Copyists' errors do occur, but there are only rare instances of totally erroneous reports, none of which is provably the result of politically-motivated manipulation.

  7. Hans Christian Ørsted reading nature's mind

    CERN Document Server

    Christensen, Dan Charly

    2013-01-01

    Hans Christian Orsted (1777-1851) is of great importance as a scientist and philosopher far beyond the borders of Denmark and his own time. At the centre of an international network of scholars, he was instrumental in founding the world picture of modern physics. Orsted was the physicist who brought Kant's metaphysics to fruition. In 1820 his discovery of electro-magnetism, a phenomenon that could not possibly exist according to his adversaries, changed the course of research in physics. It inspired Michael Faraday's experiments and discovery of the adverse effect, magneto-electric induction. The two physical phenomena were later described in mathematical equations by J.C. Maxwell. Together these discoveries constitute the prerequisites for the overwhelming development of modern technology. But Orsted was also one of the cultural leaders and organizers of the Danish Golden Age (together with Grundtvig, Kierkegaard, and Hans-Christian Andersen, his protege), and made significant contributions to aesthetics, ph...

  8. La location de l'usage : une interprétation écoresponsable du service ? : cas des biens en partage

    OpenAIRE

    Carry, Dominique,

    2013-01-01

    Des offres de location de biens en partage fleurissent dans les villes : Vélib’, Autolib’, l’autopartage.... Louer l’usage suppose de partager l’utilisation du bien à plusieurs et d’accepter de se dégager de la matérialité au profit de la fonctionnalité. C’est aussi un argument en faveur d’une consommation plus écoresponsable. Louer l’usage d’un bien en partage ou l’acheter, qu’en pense le consommateur ? La valeur réside dans les bénéfices qu'il retire de l’utilisation, et non de la possessio...

  9. La protección de bienes urbanos. Avances en la política pública de Medellín

    OpenAIRE

    Clara In��s Atehortúa-Arredondo

    2010-01-01

    La problemática de la protección de bienes en el país es una pregunta obligatoria para quienes tienen dentro de su labor el reconocimiento, la restitución y la reparación de las víctimas del desplazamiento forzado. Uno de los puntos que deben analizarse dentro de esta problemática es lo concerniente a la protección de bienes urbanos y cuya responsabilidad está en cabeza de los municipios. El desarrollo de una política pública por parte de la ciudad de Medellín para la protección de bienes es ...

  10. Hans von Hattingberg (1879-1944) Leben und Werk

    OpenAIRE

    Keifenheim, Katharina Eva

    2011-01-01

    Hans von Hattingberg, geboren am 18.11.1879 in Wien, wird heute vor allem mit dem Deutschen Institut für Psychologische Forschung und Psychotherapie („Göring-Institut“) in Verbindung gebracht, wo er sich mit der „Neuen Deutschen Seelenheilkunde“ und der Erarbeitung von „Thesen zur Neurosenlehre“ befasste. Interessanterweise war Hattingberg bis 1932 eher eine Randfigur in der Psychotherapeutenszene und galt vielen als unbelehrbarer Querulant. Viele seiner Arbeiten wurden nie veröffentlicht, u...

  11. Hereditary Breast Cancer in the Han Chinese Population

    OpenAIRE

    CAO, WENMING; Wang, Xiaojia; Li, Ji-Cheng

    2013-01-01

    Breast cancer is the most common malignancy among women and has a strong genetic background. So far, 13 breast cancer susceptibility genes of high or moderate penetrance have been identified. This review summarizes findings on these genes in Han Chinese. BRCA1 and BRCA2 are the 2 most important susceptibility genes. They have a relatively low mutation rate, and the most frequent sites of mutation are in exon 11. Frameshift mutations are the main type of mutation. Founder mutations may also ex...

  12. Xue Han Zi: using multimedia to teach chinese

    OpenAIRE

    Lam, Sun; Oliveira, Alexandre Rocha; Lavender, Tony; Cabral, Luís; Marcos, Adérito

    2001-01-01

    As the Chinese-speaking areas are becoming the focus of the world economy, more and more people are attracted by their language and culture. The number of beginners in Chinese language is growing rapidly. Although the Chinese language has unique characteristics, there are still very few teaching and learning materials which serve the basic needs for starting the acquisition of Han Zi. A multimedia application, both in CD-ROM and on-line, can provide a virtual teacher for understanding a...

  13. Hans Rottenhammer's Four Elements in Bückeburg

    Czech Academy of Sciences Publication Activity Database

    Dobalová, Sylva

    Marburg : Jonas Verlag, 2007 - (Borggrefe, H.; Lüpkes, V.; Konečný, L.; Bischoff, M.). s. 124-138 ISBN 978-3-89445-395-4 R&D Projects: GA ČR GA408/05/0753 Institutional research plan: CEZ:AV0Z80330511 Keywords : Hans Rottenhammer * Bückeburg * mannerism Subject RIV: AL - Art, Architecture, Cultural Heritage

  14. Population Exposure to Depleted Uranium in the Han Pijesak Region

    OpenAIRE

    Zora S. Žunić; Rodoljub Simović; Zoran Ćurguz; Olivera Čuknić; Jerzy Mietelski; Predrag Ujić; Igor Čeliković; Predrag Kolarž; Branko Predojević

    2011-01-01

    In September 1995 the Han Pijesak area of Republic of Srpska was heavily attacked by Depleted Uranium (DU) ammunition. In this area, from 2003 to 2004, during one year, the components of natural ionizing radiation sources like radon, thoron, and gamma radiation were measured. In addition, during the same period, the samples of soil, moss, and lichen were collected in order to identify the content of technologically enhanced natural radionuclides in them and particularly their isotopic ratios,...

  15. Smooth Cepstrum Calculation Using Modified Bartlett Hanning Window

    OpenAIRE

    Prof. Rajiv Saxena; Rohit Pandey

    2012-01-01

    Cepstrum is an algorithm for analyzing the speech signals in frequency domain. This is conventional method of fundamental peak picking i.e. fundamental frequency or pitch. For a speech signal it is necessary to identify the fundamental frequency correctly in order to have robust system for speaker identification and verification. Using this approach two algorithms has been proposed using Hamming window and Modified Bartlett Hanning Window. These algorithms involve the filtering called lifter...

  16. Conflictos por la herencia de bienes vinculados: Mujeres nobles pleiteando Conflicts for the inheritance of linked goods: Noble women going to law

    Directory of Open Access Journals (Sweden)

    Marcela Correa Barboza

    2012-12-01

    Full Text Available La casa, el parentesco, la clientela son vínculos que estructuran a conjuntos de individuos relacionados entre ellos, permitiéndoles actuar como agentes sociales colectivos. En las sociedades alto-modernas, de carácter patriarcal, las mujeres se encontraban supeditadas a la autoridad del varón, siendo éste quien actuaba socialmente, estableciendo diferentes vínculos entre familias, parientes, etc; relaciones a las que las mujeres quedaban sujetas en gran medida. Sin embargo, la historia de las mujeres ha mostrado que ellas tenían un accionar muy activo, eran capaces de intervenir en los vínculos ya existentes de manera decisiva, entablaban alianzas y promovían importantes redes de relaciones, que muchas veces encabezaban. En los últimos veinte años, se han puesto de relieve nuevas fuentes y nuevas categorías que enriquecen los estudios y propician otras formas de mirar la documentación. La utilización de la categoría género en el análisis ha permitido redimensionar el lugar de las mujeres en la historia. En los casos que presentaremos y en los temas que abordaremos, podremos observar las formas en que las mujeres de la muy alta nobleza actúan como verdaderas cabeza de linajes, defendiendo intereses propios, pero sobre todo colectivos - los de su familia-, buscando en los vericuetos legales las formas de conseguir cierto patrimonio, de mantenerlo en su círculo más cercano y, al mismo tiempo, de aumentarlo si consideran la posibilidad de acceder a nuevos bienes a través de herencias, compras, intercambios, etc.The house, kinship, the clientele are links that structure to sets of individuals related to each other, enabling them to act as collective social agents. In high-modern societies, the patriarchal nature, women were subject to male authority, this being who acted socially, establishing links between different families, relatives, etc., relations which women were subject to a great extent. However, women's history has

  17. CROSS SECTIONAL STUDY OF NUTRITIONAL STATUS IN OLDER HAN WOMEN.

    Science.gov (United States)

    Jun, Tao; Yuan, Zhong

    2016-01-01

    Abstract. Malnutrition is one of the most prevalent problems in older people, but there is little information about the nutritional status of the older women in China. Therefore, this study was conducted to investigate the nutritional status and clinically correlated factors for malnutrition in older Han women in China. In total, 2,556 hospital- and community-based Han women aged 60 years or older were recruited between May 2007 and December 2014. All women completed comprehensive geriatric assessment, and the Mini Nutritional Assessment Short Form (MNA-SF) was used to assess the nutritional status. The clinically corre- lated factors for malnutrition were also analyzed, including social factors, health status, and dietary behavior. The average age of these women was 75.9 ± 9.4 years, and 63.8% women lived in urban areas. Of the total respondents, 344 and 716 women were classified as malnutrition and at risk of malnutrition, respectively. Five factors were independently and positively correlated with poor nutrition, including chronic obstructive pulmonary disease (COPD), gastrointestinal disease, depression, cognitive impairment, and comorbidity (≥ 2). Three factors were independently and negatively correlated with poor nutrition, including economic status, meat intake, and fish intake. The older Han women with these five health problems should be given more attention with regards to their nutritional status. Improving economic status, eating more meat and fish were recommended for preventing poor nutrition in older women. PMID:27086430

  18. Freud's Little Oedipus: Hans as exception to the oedipal rule.

    Science.gov (United States)

    Ahbel-Rappe, Karin

    2008-09-01

    Freud's "The Analysis of a Phobia in a Five-Year-Old Boy" is regarded by Freud and by analytic readers and commentators as a prototype of his conception of the oedipus complex. A literary methodology is used to show that the interpretation of the oedipus complex at work in Freud's text in fact differs from Freud's standard view of it. While studying the paper as text, not as case report, may obscure or distort some clinical matters, it is valuable in that it makes legible a sort of theoretical unconscious in the text. In contrast to Freud's typically tragic view of the oedipus complex (in the tradition of ancient Greek tragedy), the Hans study evokes a comic vision (in the tradition of Greek New Comedy). This comic vision allows Hans a happy imaginative ending to the oedipal dilemma, challenges certain epistemic pretensions, and emphasizes the oedipus complex as a set of abiding existential questions. Given the deep link between Freud"s oedipus concept and a tragic view of human life, this departure in the Hans paper is a fascinating anomaly. PMID:18802132

  19. Assessment and Upgrading of the Novi Han Monitoring System (Bulgaria)

    International Nuclear Information System (INIS)

    The tasks of this project can be summarised as follow. The site assessment has produced the following outputs: the Novi Han team has practiced the sampling of soils, sediments and vegetation, the on-site and laboratory analysis have not shown any significant release from the vaults with the exception for 3H that has been detected in significant concentration in water samples collected from boreholes. The critical analysis of the current monitoring program and the laboratory equipment have revealed some weak points. Remedial measures have been proposed where and when required. An evolutional monitoring program has been defined in accordance with the EC recommendations and the budget required to its implementation has been estimated. A 2 weeks training has been organized in Belgium for 2 peoples from Novi Han repository; the training was focused on methods required by the monitoring program. Four QA analytical procedures have been written by the trainees and have been verified by the IRE. The skeleton of a radiological database has been drafted; its realization is far beyond the scope of the current project and is strongly linked to the QA system anyway. The priority equipments needed for the implementation of the monitoring program have been defined in agreement with the Novi Han staff. Priority equipment have been purchased in the limits of budget. (author)

  20. Administración económica del distrito inquisitorial de Valencia: la receptoría de bienes confiscados (1482-1493)

    OpenAIRE

    Tomás Botella, Bernardo

    2016-01-01

    El objeto de esta tesis doctoral es la receptoría de bienes confiscados de la Inquisición de Valencia, su estructura burocrática y sus procedimientos de actuación sobre la sociedad valenciana bajomedieval. Esta oficina se encargaba de ejecutar el secuestro y confiscación del patrimonio de los herejes condenados, así como de gestionar y liquidar dichos bienes una vez incorporados al fisco regio. Además, se ha analizado la evolución institucional que experimentó el Santo Oficio durante el perio...

  1. Gasto particularista en bienes públicos locales: índice de desviación Particularistic expenditure on local public goods: an index of deviation

    OpenAIRE

    María Alejandra Armesto

    2012-01-01

    El gasto particularista del gobierno se opone al gasto programático. Los dos tipos de medidas clasifican los beneficios de políticas como particularistas si son bienes exclusivos o si son explicados por variables políticas. Este artículo desarrolla un índice de gasto particularista en bienes públicos locales medido como desviación con respecto al programa. Se aplica el índice a la oferta de servicios básicos por administraciones subnacionales seleccionadas en México y Argentina. Se muestra qu...

  2. Una aproximación a los factores claves para la gestión de los bienes de patrimonio cultural

    OpenAIRE

    Fresneda Fuentes, Silvia; Lobo Gallardo, Antonio

    2014-01-01

    El turismo cultural está basado en la gestión y explotación, entre otros, de los bienes catalogados como patrimonio cultural. La necesidad de obtener resultados positivos ha generado una preocupación creciente por identificar los factores clave de éxito. El principal objetivo de este trabajo ha sido la identificación de los mismos, para lo que se ha realizado una revisión bibliográfica. Entendemos que la gestión de estos bienes se debe abordar de la lógica de la mejora continua y una perspect...

  3. Competitividad de la industria de bienes de equipo de España y Alemania (1993-2008): ventaja absoluta y costes relativos

    OpenAIRE

    Boundi Chraki, Fahd

    2014-01-01

    El presente trabajo realizará un análisis comparativo del sector de bienes de equipo de España y Alemania, con el objeto de desentrañar los determinantes de la competitividad de esta industria. La hipótesis central es la siguiente: la industria de bienes de equipo de Alemania es más competitiva debido a su mayor productividad real y sus menores costes relativos. De este modo, se partirá de la teoría clásica y marxiana de la formación de los precios, y el modelo de las ventajas absolutas de An...

  4. Determinación de los precios implícitos en bienes inmuebles : una alternativa a la modelización hedónica

    OpenAIRE

    Ceular Villamandos, Nuria; Caridad y Ocerin, José María

    2004-01-01

    RESUMEN Recientemente un nuevo enfoque para estimar el valor de bienes inmuebles está siendo cada vez más usado. Para ello se usan atributos internos del bien, y externos, del entorno, pues ambos son percibidos de forma diferente en el mercado. Así pues, propiedades con nivel de precios similar son consideradas como claramente diferenciadas en los mercados inmobiliarios. Las técnicas de Inteligencia Arti cial proporcionan nuevas posibilidades, en comparación con la modelización econométrica ...

  5. Los bienes habices y la repoblación de Andalucía en el siglo XIII : el caso de Sevilla

    OpenAIRE

    García Sanjuán, Alejandro

    1999-01-01

    Los legados piadosos o bienes habices constituyen una de las instituciones socioeconómicas islámicas más relevantes durante la Edad Media. Dichos bienes, jurídicamente inalienables, proceden de donaciones voluntarias realizadas por los creyentes musulmanes para cualquier finalidad considerada piadosa desde un punto de vista islámico, de manera particular a favor de pobres y enfermos, para el rescate de prisioneros, para contribuir al sostenimiento de las fronteras y al esfuerzo por defender ...

  6. "La política de reparto de bienes comunales en el municipio de San Juan Parangaricutiro (1861-1980)"

    OpenAIRE

    Saenz Gallegos, Catalina

    2012-01-01

    La historia de Michoacán no se concibe sin los movimientos sociales de la lucha por la tierra, en que las Comunidades indígenas no han sido ajenas, muestra de ello es que en la actualidad se sigan resistiendo a perder la posesión de sus territorios. Es por ello, que históricamente podemos entender que el Estado de Michoacán sea considerado por la Secretaría de la Reforma Agraria como uno de los focos Rojos del país, ya que el problema por la tierra ha sido un proceso hist...

  7. El castellano bien templado

    OpenAIRE

    Sáenz, Miguel

    2009-01-01

    Este artículo se sirve de la música para establecer un paralelismo entre ésta y la traducción, pues si la traducción es una interpretación (musical) de un texto, puede haber innumerables traducciones válidas, pudiendo haber alguna “de referencia”. Además, se plantea que las facultades son como conservatorios donde los futuros traductores estudian técnicas y aprenden fundamentos teóricos (que compara con el solfeo, la armonía y la composición) y que las traducciones “envejecen” porque su es...

  8. Differences in Platelet Indices between Healthy Han Population and Tibetans in China

    OpenAIRE

    Niu, Qian; Zhang, Ruke; Zhao, Min; Zeng, Sugen; Huang, Xunbei; Jiang, Hong; An, Youfang; Zhang, Luwen

    2013-01-01

    Introduction The present data on the evaluation of platelet (PLT) parameters in Chinese Han population and Tibetans are still limited. The objective of this study was to determine the differences in common PLT indices between Han population and Tibetans in China, through a large-scale investigation of healthy people. Methods 2131 Han people from Chengdu Plain, 1099 Tibetans from Qinghai-Tibet Plateau and 956 Plateau Han migrants were included in this study. All the subjects were healthy peopl...

  9. El vivir bien, una propuesta de los pueblos indígenas a la discusión sobre el desarrollo (Living well, a proposal from indigenous people to the development discussion

    Directory of Open Access Journals (Sweden)

    Elisa Canqui Mollo

    2011-07-01

    Full Text Available ResumenÚltimamente hay una conciencia global sobre que la noción de desarrollo está pasando por serios procesos de crítica y reconstrucción, por las connotaciones evolucionistas y eurocéntricas predominantes en sus principales formulaciones, pensadas de cara a la construcción y ampliación de estados nacionales y de un proyecto económico y cultural dirigido a una progresiva modernización capitalista homogénea que busca la creciente satisfacción material e individual, fundada en formas que han amenazado con subordinar y transformar otros principios, culturas y conocimientos a su imagen y semejanza. Es en este marco, que el Vivir Bien, propuesta por los Pueblos Indígenas viene a sumarse a las distintas propuestas que han ido saliendo en cuanto a desarrollo se refiere. Esta propuesta comprendida por ellos como una traducción de las formas y estilos de vida, en su simplicidad muestra una compleja articulación entre la vida de los indígenas, sus recursos naturales y el vínculo estrecho entre ambos, dentro de un territorio.AbstractIn recent times there is a global awareness of the fact that the notion of development is going through a process of criticism and reconstruction, due to the evolutionary and Eurocentric connotations in its formulation, which is oriented to the construction and expansion of nation-states and an economic and cultural project led to a progressive and homogeneous capitalist modernization, aimed at increasing individual and material satisfaction. Those forms have threatened to subordinate and transform other principles, culture and knowledge. In this context we find the proposal of the indigenous peoples of Living Well. This proposal, understood by them as a translation of forms and lifestyles, shows in its simplicity, a complex articulation between the life of indigenous, their natural resources and the close link between them within a territory.

  10. Créations graphiques réussissez vos brochures, logos, pages web, newsletters, flyers, et bien plus encore !

    CERN Document Server

    McWade, John

    2010-01-01

    Dans cet ouvrage, qui regroupe un florilège des meilleurs projets professionnels publiés dans son célèbre magazine de graphisme, Before & After, John McWade offre une présentation approfondie des principes de base du graphisme, avant de partager concrètement techniques et procédés. Dans un style simple et convivial, il analyse différentes créations graphiques abouties – brochures, lettres d'information, sites web, cartes de visite et autres supports visuels – et explique le pourquoi et le comment de leur réussite. À votre tour, inspirez-vous de ces exemples et employez ces mêmes techniques à l'envie pour améliorer vos propres documents. Vous apprendrez à: rogner des photos pour parfaire leur fonction et leur signification; attirer le regard du lecteur à l'emplacement souhaité à l'aide de huit solutions différentes; travailler sur les composants de base de la création graphique, tels que le trait, la forme, la direction, le mouvement, la mise à l'échelle, la couleur, et bien d'a...

  11. El consumo de bienes religiosos. Una introducción económica al caso español

    Directory of Open Access Journals (Sweden)

    Brañas-Garza, Pablo

    2003-08-01

    Full Text Available This paper uses the Economic of Religion issues to explore Spanish religious behaviour. Under this microeconomic framework religious practise is considered "rational" using Azzi-Ehrenberg (1975 arguments: salvation, social and professional motives. We test if that hypotheses may explain Spanish religious activity. To this end we run descriptive and multivariate analysis that allows us to conclude the following: theoretical models well perform Spanish data; gender, ageing, family size and education are positive determinant of church-attendance; the influence of parents behaviour on children religious activity.

    Este trabajo explora el comportamiento religioso de los españoles desde el enfoque de la Economía de la Religión. En un marco microeconómico y utilizando los argumentos de Azzi- Ehrenberg (1975 —motivo salvación, consumo y profesional—, la práctica religiosa resulta racional. En esta investigación estudiamos si estas hipótesis pueden explicar el comportamiento religioso de los españoles. Para ello se realizan análisis descriptivos y multivariantes que nos permiten concluir que: los modelos teóricos explican bien los datos españoles; que el sexo, la edad, el tamaño de la familia y la educación son determinantes positivos de la asistencia a iglesia; que el ejemplo de los padres influye en la actividad religiosa actual de los hijos.

  12. Profanum et Promissio: het begrip wereld in de missionaire ecclesiologieën van Hans Hoekendijk, Hans Jochen Margull en Ernst Lange

    OpenAIRE

    Petter, Frank Anthonie

    2002-01-01

    Profanum et Promissio The concept of ‘world’ in the missionary ecclesiologies of Hans Hoekendijk, Hans Jochen Margull and Ernst Lange. This study deals with the concept of ‘world’ in the missionary ecclesiologies of Hans Hoekendijk (1912-1975), Hans Jochen Margull (1925-1982) and Ernst Lange (1927-1974). The development of missionary ecclesiology is related to the integration of ‘church’ and ‘mission’ in the ecumenical movement of the first half of the twentieth century. This integration led ...

  13. Ibn Arabi – en sufimystiker og hans læremestre

    DEFF Research Database (Denmark)

    Ehrensvärd, Martin Gustaf

    2005-01-01

    Ibn 'Arabi¯ (1165-1240) er blandt de mest indflydelsesrige og kontroversielle islamiske mystikere, kendt blandt hans tilhængere som ’den største mester’ og blandt hans modstandere som ’den største kætter’. Af hans meget omfattende forfatterskab foreligger der indtil videre kun nogle fa° sider i...

  14. Formation of THMs and HANs during bromination of Microcystis aeruginosa

    Institute of Scientific and Technical Information of China (English)

    Yunzhu Pu; Lingzhao Kong; Xin Huang; Guoji Ding; Naiyun Gao

    2013-01-01

    Bromine-contained disinfectants and biocides are widely used in swimming pools,recreational waters and cooling towers.The objective of this study was to evaluate the formation of thrihalomethanes (THMs) and haloacetonitriles (HANs) and their cytotoxicity in algae solutions during free bromine disinfection.Disinfection by-products formation potential experiments were conducted using modelsolutions containing 7mg/L (as total organic carbon) Microcystis aeruginosa cells.Effects of free bromine dosage,pH and ammonia were investigated.The results showed that brominated disinfection by-products were the major products when free bromine was applied.The total THMs formed during bromination was much as that formed during chlorination,whereas HANs were elevated by using bromination instead of chlorination.Dibromoacetonitrice (C2H2NBr2) and bromoform (CHBr3) were the only detected species during free bromine disinfection.The production of C2H2NBr2 and CHBr3 increased with disinfectant dosage but decreased with dosing ammonia.CHBr3 increased with the pH changing from 5 to 9.However,C2H2NBr2 achieved the highest production at neutral pH,which was due to a joint effect of variation in hydrolysis rate and free bromine reactivity.The hydrolysis of C2H2NBr2 was basecatalytic and nearly unaffected by disinfectant.Finally,estimation of cytotoxicity of the disinfected algae solutions showed that HANs formation was responsible for the majority of toxicity.Considering its highest toxicity among the measured disinfection by-products,the elevated C2H2NBr2 should be considered when using bromine-related algaecide.

  15. Release of ammonia from HAN-type PHA

    International Nuclear Information System (INIS)

    A preliminary design basis for ammonia scrubbers in the DWPF has been issued. This design basis is based on a theoretical model of ammonia evolution from the SRAT, SME and RCT. It is desirable to acquire actual process data on ammonia evolution prior to performing detailed design of scrubbers for DWPF. The evolution of ammonia from the SRAT and SME in the Integrated DWPF Melter System (IDMS) was investigated during the HM4 run. In this run, Precipitate Hydrolysis Aqueous (PHA), which was made in the Precipitate Hydrolysis Experimental Facility (PHEF) using the HAN (hydroxylamine nitrate) process was used, thus resulting in PHA with a high concentration of ammonium ion

  16. Reconstruction and modernization of Novi Han radioactive waste repository

    International Nuclear Information System (INIS)

    The paper is an overview of the Feasibility Study for Reconstruction and Modernisation of Novi Han Radioactive Waste Repository (NHRWR), performed by EQE Bulgaria AD in 2000 for the Institute for Nuclear Research and Nuclear Energy of the Bulgarian Academy of Sciences. The Study develops a concept for overall reconstruction and modernisation of NHRWR, including rehabilitation and partial reconstruction of existing facilities and planning of new facilities for conditioning and storage of various radioactive wastes and spent sealed sources. The paper presents the general modernisation concept and outlines the proposed principle technical solutions for the existing and new facilities. (author)

  17. WENNEKÜLLA HANS AND ESTONIAN CHURCH LANGUAGE

    Directory of Open Access Journals (Sweden)

    Aivar Põldvee

    2012-01-01

    Full Text Available In the 17th century two Estonian literary languages were standardised. As literary language was needed primarily for translating ecclesiastical texts and for worship services, it evolved as a church language that was created mainly by German pastors, following the example of the German language. At the end of the 17th century, in connection with the translation of the Bible and the establishment of Estonian schools, there emerged a need to renew the literary language and make it more approachable for the common people. The reforms created a situation where church manuals that differed in dialects,orthography and wording were used simultaneously. The case of Wennekülla Hans in the year 1700 demonstrates how a peasant reacted to that confusion. Wennekülla Hans, who was a self-appointed preacherin the parish of Paistu/Paistel, got caught up in a conflict with the pastor Andreas Hornung, who belonged to the circle of language innovators.The peasant accused the pastor of false teaching because the pastor was using a church manual with a modified language version.The case is one of the earliest examples of the evolution of a literary language into a sociolect that was used not only by clergymen but by peasants as well.

  18. Complete blood count reference intervals for healthy Han Chinese adults.

    Directory of Open Access Journals (Sweden)

    Xinzhong Wu

    Full Text Available Complete blood count (CBC reference intervals are important to diagnose diseases, screen blood donors, and assess overall health. However, current reference intervals established by older instruments and technologies and those from American and European populations are not suitable for Chinese samples due to ethnic, dietary, and lifestyle differences. The aim of this multicenter collaborative study was to establish CBC reference intervals for healthy Han Chinese adults.A total of 4,642 healthy individuals (2,136 males and 2,506 females were recruited from six clinical centers in China (Shenyang, Beijing, Shanghai, Guangzhou, Chengdu, and Xi'an. Blood samples collected in K2EDTA anticoagulant tubes were analyzed. Analysis of variance was performed to determine differences in consensus intervals according to the use of data from the combined sample and selected samples.Median and mean platelet counts from the Chengdu center were significantly lower than those from other centers. Red blood cell count (RBC, hemoglobin (HGB, and hematocrit (HCT values were higher in males than in females at all ages. Other CBC parameters showed no significant instrument-, region-, age-, or sex-dependent difference. Thalassemia carriers were found to affect the lower or upper limit of different RBC profiles.We were able to establish consensus intervals for CBC parameters in healthy Han Chinese adults. RBC, HGB, and HCT intervals were established for each sex. The reference interval for platelets for the Chengdu center should be established independently.

  19. Molecular characterization of a Han Chinese family with essential hypertension.

    Science.gov (United States)

    Zhu, J F; Zhang, X; Ling, L

    2016-01-01

    Mutations in the mitochondrial genome have been found to be associated with essential hypertension. Here, we report the clinical and molecular characterization of a three-generation Han Chinese family with maternally inherited hypertension. Most strikingly, this pedigree exhibited a high penetrance of hypertension. Sequence analysis of the mitochondrial genome showed the presence of a homoplasmic T16189C mutation in the D-loop and the intergenic CO2/tRNA(Lys) 9-bp common deletion, as well as a set of polymorphisms belonging to the East Asia haplogroup B5b1. The well-known T16189C mutation, which is in the first hypervariable segment of the mitochondrial control region, is implicated to be associated with a wide range of clinical disorders. Moreover, the genetic polymorphism 9-bp common deletion is found to be associated with hepatocellular carcinoma in the Han Chinese population. Thus, the combination of T16189C mutation and the 9-bp deletion may have caused mitochondrial dysfunction and contributed to the development of essential hypertension in this Chinese family. PMID:27323027

  20. The anatomist Hans Elias: A Jewish German in exile.

    Science.gov (United States)

    Hildebrandt, S

    2012-04-01

    Hans Elias (1907 to 1985) was an anatomist, an educator, a mathematician, a cinematographer, a painter, and a sculptor. Above all, he was a German of Jewish descent, who had to leave his home country because of the policies of the National Socialist (NS) regime. He spent his life in exile, first in Italy and then in the United States. His biography is exemplary for a generation of younger expatriates from National Socialist Germany who had to find a new professional career under difficult circumstances. Elias was a greatly productive morphologist whose artistic talent led to the foundation of the new science of stereology and made him an expert in scientific cinematography. He struggled hard to fulfill his own high expectations of himself in terms of his effectiveness as a scientist, educator, and politically acting man in this world. Throughout his life this strong-willed and outspoken man never lost his great fondness for Germany and many of its people, while reserving some of his sharpest criticism for fellow anatomists who were active in National Socialist Germany, among them his friend Hermann Stieve, Max Clara, and Heinrich von Hayek. Hans Elias' life is well documented in his unpublished diaries and memoirs, and thus allows fresh insights into a time period when some anatomists were among the first victims of NS policies and other anatomists became involved in the execution of such policies. PMID:22038841

  1. Manipulación mediática, identidad juvenil y prostitución de un bien necesario

    Directory of Open Access Journals (Sweden)

    Alexander Mosquera

    2007-01-01

    Full Text Available Algo que identifi ca al joven de hoy es la telefonía móvil, una nueva tecnología que invade todas las esferas de lavida pública y privada, cuya presencia se hace sentir a través de una multiplicidad de “ring-tones”. Este trabajo tienecomo objetivo general describir la interrelación que se da entre la manipulación de los medios a través del discursopublicitario sobre celulares, la construcción de la identidad juvenil y la prostitución de lo que otrora fuera un bien necesariocomo el teléfono. Se abordó un corpus compuesto por varios avisos publicitarios que circularon en los diariosvenezolanos El Nacional, La Verdad y Panorama durante agosto de 2005, desde la perspectiva teórico-metodológicade la semiótica crítica de González de Ávila y de la semiótica de la cultura de Lotman. También se utilizaron algunosaportes de Magariños de Morentin relacionados con la semiótica de los mensajes publicitarios, así como los de Caro Almela, Bourdieu, Pasquali y Eco sobre los mass-media. Los resultados revelaron una manipulación mediática a través del discurso publicitario, dirigida a crear la urgente necesidad de poseer un celular, porque éste es el signo-mercancía con el cual se identifi ca el joven actual. Una conclusión preliminar indica que la no-posesión de ese aparato hace aparecer al joven como un “excluido” de ese mundo de la telefonía móvil.

  2. Hans H. Ussing - scientific work: contemporary significance and perspectives

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid

    2002-01-01

    As a zoologist, Hans H. Ussing began his scientific career by studying the marine plankton fauna in East Greenland. This brought him in contact with August Krogh at the time George de Hevesy, Niels Bohr and Krogh planned the application of artificial radioactive isotopes for studying the dynamic...... exchange diffusion, unidirectional fluxes, flux-ratio equation, and solvent drag. Combining methods of biophysics with radioactive isotope technology, Ussing introduced and defined the phrases ‘short-circuit current', ‘active transport pathway' and ‘shunt pathway', and with frog skin as experimental model...... skin bridged studies of high and low resistance epithelia and generalized the description of epithelial transport. He devoted the last decade of his scientific life to solute-coupled water transport. He introduced the sodium recirculation theory of isotonic transport, and in an experimental study, he...

  3. Moessbauer study of a Western-Han dynasty pottery figure

    International Nuclear Information System (INIS)

    A grey pottery figure manufactured in the Western-Han Dynasty and the clay gathered from the same site of Beidongshan near Suzhou, China, have been studied by X-ray diffraction, X-ray fluorescence and Moessbauer spectroscopy. They were simultaneously fired under the same conditions in different atmospheres at various temperatures. The information on original firing atmosphere and temperature as well as its provenance can be inferred from the method of pottery re-firing and clay firing. The original firing temperatures deduced from both of them are in good self-agreement. It is found that the values of Moessbauer parameters for the un-re-fired pottery figure are approximately the same as those for the clay fired at 950 deg C for five hours in a reduced atmosphere. The XRF analysis confirmed that the locality of this pottery figure was somewhere near Beidongshan

  4. Smooth Cepstrum Calculation Using Modified Bartlett Hanning Window

    Directory of Open Access Journals (Sweden)

    Prof. Rajiv Saxena

    2012-03-01

    Full Text Available Cepstrum is an algorithm for analyzing the speech signals in frequency domain. This is conventional method of fundamental peak picking i.e. fundamental frequency or pitch. For a speech signal it is necessary to identify the fundamental frequency correctly in order to have robust system for speaker identification and verification. Using this approach two algorithms has been proposed using Hamming window and Modified Bartlett Hanning Window. These algorithms involve the filtering called liftering after converting the speech sample to Cepstrum domain (Quefrency domain. The utility of using filtering in cepstrum domain has been analyzed as window functions play vital role in deciding the fundamental peak of the speech sample. Gross Pitch Estimation Error has been calculated with smooth cepstrum and smooth cepstrum with autocorrelation in order to calculate false acceptance and rejection rate for two speakers respectively.

  5. Selected Works Of Hans A Bethe (With Commentary)

    International Nuclear Information System (INIS)

    Hans A Bethe received the Nobel Prize for Physics in 1967 for his work on the production of energy in stars. A living legend among the physics community, he helped to shape classical physics into quantum physics and increased the understanding of the atomic processes responsible for the properties of matter and of the forces governing the structures of atomic nuclei. This collection of papers by Prof Bethe dates from 1928, when he received his PhD, to now. It covers several areas and reflects the many contributions in research and discovery made by one of the most important and eminent physicists of all time. Special commentaries have been written by Prof Bethe to complement the selected papers

  6. La economía social y solidaria como alternativa económica. Bienes comunes y democracia

    Directory of Open Access Journals (Sweden)

    Jaime Abad Montesinos

    2014-10-01

    Full Text Available Normal 0 21 MicrosoftInternetExplorer4 Resumen: El presente artículo trata de enmarcar la economía social y solidaria en el seno del actual debate producto de la crisis económica vigente, haciendo especial hincapié en las cuestiones relacionadas con los bienes comunes y la gestión democrática. La crisis presente ha puesto de manifiesto la necesidad de proponer modelos socio-económicos alternativos que aúnen democracia, compromiso social y sostenibilidad del medio ambiente. La economía social y solidaria, sin ser un programa homogéneo, está contribuyendo a proponer respuestas a algunos de los problemas actuales en materia de desempleo e integración social, revalorizando en los procesos económicos, no sólo los intercambios mercantiles, sino también los intereses sociales y los recursos naturales. Abstract:This article aims to enlighten the importance ofsolidary and social economy in the present discussion, whose importance has increased as a result of the current economic crisis, making a special emphasis on subjects such as commons goods and democratic management. The crisis has brought up the need for alternative socio-economical management models which must combine democracy, social commitment and environmental sustainability. Solidary and social economy, without being a homogeneous program, are proposing answers to some of the present problems related to unemployment and social integration, contributing to increase the value of economic processes, not only in commercial exchanges, but also the social interest and natural resources. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} /* Style Definitions */ table.MsoNormalTable {mso

  7. Prolegómenos al vivir bien-buen vivir: una evaluación normativa y práctica

    Directory of Open Access Journals (Sweden)

    Edwin Cruz Rodríguez

    2015-06-01

    Full Text Available Este trabajo examina el concepto de vivir bien-buen vivir ponderando sus contribuciones y limitaciones. Esta cosmovisión tiene un horizonte normativo más ambicioso que el paradigma del desarrollo, pues apuesta por una concepción de la pobreza y la riqueza que no se reduce a la acumulación de bienes materiales, una economía que comprende sus efectos sobre la naturaleza y se centra en la satisfacción de necesidades, y una descolonización de los saberes. No obstante, se caracteriza por un déficit de operacionalización que se manifiesta en la dificultad para definir políticas concretas e indicadores de medición precisos.

  8. “Jeneros de gusto y sobretodos ingleses”: el impacto cultural del consumo de bienes ingleses por la clase alta bogotana .

    Directory of Open Access Journals (Sweden)

    Ana Maria Otero Cleves.

    2009-05-01

    Full Text Available Este artículo analiza el impacto cultural del consumo de bienes Inglés por la clase alta de Bogotá durante el siglo XIX. Se sugiere que el consumo de productos Inglés después de la independencia del país fue uno de los principales mecanismos empleados por las clases altas para asegurar su posición social, así como para construir una nación moderna, de acuerdo a las normas europeas. Por lo tanto, el artículo analiza el papel que el consumo de bienes extranjeros en el proceso de construcción de la nación y la diferenciación social en el siglo XIX.

  9. Ethique de la population : l'apport des critères de bien-être dépendant du rang

    OpenAIRE

    Zuber, Stéphane

    2016-01-01

    Cet article présente l'intérêt que peuvent avoir des critères de bien-être dépendant du rang dans le cadre de l'éthique de la population. Ce champ de recherche s'intéresse à l'évaluation et à la comparaison d'allocations lorsque des populations de tailles différentes sont en jeu. On montre que les critères de bien-être dépendant du rang ne sont pas sujets à plusieurs écueils auxquels sont confrontés les critères utilitaristes (généralisés) habituellement étudiés dans ce champ....

  10. Fuentes de información para el diseño de un Sistema de Vigilancia e Inteligencia en el Registro Provincial de Bienes Culturales de Matanzas

    Directory of Open Access Journals (Sweden)

    Justa Bielka Cantillo González

    2007-01-01

    Full Text Available Por la importancia que reviste la conservación del Patrimonio Cultural, se identifican, con la utilización de herramientas estadísticas (Coeficiente de Concordancia de Kendall las fuentes de información relevantes, para el posterior diseño de un Sistema de Vigilancia e Inteligencia en el Registro Provincial de Bienes Culturales de la provincia de Matanzas

  11. Fuentes de información para el diseño de un sistema de vigilancia e inteligencia en el registro provincial de bienes culturales de Matanzas.

    Directory of Open Access Journals (Sweden)

    Lilian Delia Curiel Lorenzo

    2010-10-01

    Full Text Available Por la importancia que reviste la conservación del Patrimonio Cultural, se identifican, con la utilización de herramientas estadísticas (Coeficiente de Concordancia de Kendall las fuentes de información relevantes, para el posterior diseño de un Sistema de Vigilancia e Inteligencia en el Registro Provincial de Bienes Culturales de la provincia de Matanzas.

  12. El dominio público y los bienes públicos: Europa y América Latina. ¿El hijo sigue mirando al padre?

    Directory of Open Access Journals (Sweden)

    Sergio Chemás

    2015-12-01

    Full Text Available El estudio del derecho de los bienes públicos en América Latina y en Colombia es algo todavía poco desarrollado. Se sigue mirando hacia el derecho comparado para obtener respuestas, tal como un hijo mira a su padre, porque fue allá donde surgieron los grandes desarrollos del tema. El dominio público en Europa y América Latina es producto de un encuentro entre varias autoridades en el tema de los bienes públicos tanto de Europa como de América Latina. Esta reseña se divide en tres partes: i un breve análisis de derecho comparado frente al concepto de dominio público; ii la identificación de los contenidos más interesantes e innovadores de los regímenes de bienes públicos, y iii un ejercicio académico para que el lector lo desarrolle al leer el libro.

  13. Thinking styles, emotion regulation, and their roles in Tibetan college students' acculturation into Han cultural environment

    OpenAIRE

    Yong, Lin.; 雍琳.

    2013-01-01

    The increasing inter-cultural communication in China has led to a growing interest in how the ethnic minorities cope with the encountered main stream (Han)culture of China. The present research compared Tibetan and Han college students studying in a Northwest China province, examining how Tibetan college students acculturated into Han cultural environment concerning their thinking styles, emotion regulation, acculturation strategy, academic performance, and psychological well-being. The ...

  14. Leprosy type 1 reactions and erythema nodosum leprosum Reações hansênicas do tipo 1 e eritema nodoso hansênico

    Directory of Open Access Journals (Sweden)

    Indira P. Kahawita

    2008-02-01

    Full Text Available Leprosy reactions are a major cause of nerve damage and morbidity in a significant proportion of leprosy patients. Reactions are immunologically mediated and can occur even after successful completion of multi-drug therapy. This review focuses on the epidemiology, pathology and treatment of leprosy type 1 reactions, erythema nodosum leprosum and silent neuropathy.As reações hansênicas são a principal causa de dano e morbidade neural em grande parte dos pacientes hansênicos. São imunomediadas e podem ocorrer mesmo após o término bem sucedido da poliquimioterapia. Esta revisão enfoca a epidemiologia, a patologia e o tratamento das reações hansênicas do tipo 1, do eritema nodoso hansênico e da neuropatia silenciosa.

  15. Risks associated with premature ovarian failure in Han Chinese women.

    Science.gov (United States)

    Wang, Huidan; Chen, Haitao; Qin, Yingying; Shi, Zhuqing; Zhao, Xiaoming; Xu, Jianfeng; Ma, Bowen; Chen, Zi-Jiang

    2015-04-01

    In this retrospective study, the relationship between demographic characteristics, past medical history, general lifestyle habits and susceptibility of premature ovarian failure (POF) in Han Chinese population was investigated. Five hundred and fifty-three patients with POF and 400 women with normal ovarian function were recruited. A questionnaire was designed to gather information from responders. Logistic regression was carried out to calculate odds ratios (OR), 95% confidence intervals (95% CI) and P-values. History of pelvic surgery, mumps, having relatives with menstrual abnormalities and exposure to chemical agents were significantly associated with increased risk of POF (OR 5.53 [2.15 to 14.23]; 3.26 [2.38 to 4.47]; 28.12 [8.84 to 89.46]; 4.47 [2.09 to 9.58]). Vegetarian diet, tea and mineral water consumption reduced the risk of POF (OR 0.27 [0.19 to 0.37]; 0.04 [0.03 to 0.07]; 0.63 [0.47 to 0.85], respectively). Heredity, pelvic surgery, mumps and exposure to chemical agents were identified as risk factors for POF, whereas vegetarian diet, tea consumption and mineral water drinking were protective. Therefore, genetic consultation could help those women whose relatives manifested an early or premature menopause to avoid the consequences of possible premature ovarian function cessation. Avoidance of exposure to endocrine disrupters and flavonoids intake should be considered. PMID:25682306

  16. Hans Küpper discusses science and venture capital.

    Science.gov (United States)

    Küpper, Hans

    2004-11-01

    Hans Küpper has over 30 years of experience in the biotechnology industry in areas from research to R&D management, technology assessment and business acquisitions. He received his PhD in 1974 from the University of Heidelberg. After additional academic research at the Massachusetts Institute of Technology in the USA and at the University of Heidelberg, Germany, he joined Biogen in 1980. Here, he held various R&D positions, the last of which was Assistant Research Director. In 1985, he joined Behringwerke AG, Marburg, to build up and head the company's Molecular Biology Department and thereafter became Head of R&D of the Immunology/Oncology Business Unit. In 1999 he joined Global Life Science Ventures at their Munich office. Dr Küpper is the author of numerous publications and patents/applications and has also served as a consultant to the Pharmaceutical Industry and the European Commission. He is a board member of several early stage companies in the life sciences. PMID:15501722

  17. Nuclear forces the making of the physicist Hans Bethe

    CERN Document Server

    Schweber, Silvan S

    2012-01-01

    On the fiftieth anniversary of Hiroshima, Nobel-winning physicist Hans Bethe called on his fellow scientists to stop working on weapons of mass destruction. What drove Bethe, the head of Theoretical Physics at Los Alamos during the Manhattan Project, to renounce the weaponry he had once worked so tirelessly to create? That is one of the questions answered by "Nuclear Forces", a riveting biography of Bethe's early life and development as both a scientist and a man of principle. As Silvan Schweber follows Bethe from his childhood in Germany, to laboratories in Italy and England, and on to Cornell University, he shows how these differing environments were reflected in the kind of physics Bethe produced. Many of the young quantum physicists in the 1930s, including Bethe, had Jewish roots, and Schweber considers how Liberal Judaism in Germany helps explain their remarkable contributions. A portrait emerges of a man whose strategy for staying on top of a deeply hierarchical field was to tackle only those problems h...

  18. The Research on the Military Administrative Law in Han Dynasty of China

    OpenAIRE

    Han Zhang

    2014-01-01

    Military law management system is an important contribution to the Han Dynasty in China. Baselines of the military law of finds unearthed come, especially in the bamboo slats of Zhangjiajshan. This article highlights the importance of management system during the Han Dynasty law and analyzes the characteristics of military law, which allow us to understand the system of laws later dynasty.

  19. The Research on the Military Administrative Law in Han Dynasty of China

    Directory of Open Access Journals (Sweden)

    Han Zhang

    2014-12-01

    Full Text Available Military law management system is an important contribution to the Han Dynasty in China. Baselines of the military law of finds unearthed come, especially in the bamboo slats of Zhangjiajshan. This article highlights the importance of management system during the Han Dynasty law and analyzes the characteristics of military law, which allow us to understand the system of laws later dynasty.

  20. Mitochondrial DNA Haplogroups and the Risk of Sporadic Parkinson′s Disease in Han Chinese

    Directory of Open Access Journals (Sweden)

    Ya-Fang Chen

    2015-01-01

    Conclusions: Our study indicates that haplogroup B might confer a lower risk for EOPD and people younger than 50 years in Han Chinese, while haplogroup D probably lead a higher risk of PD in people younger than 50 years of age. In brief, particular Asian mtDNA haplogroups likely play a role in the pathogenesis of PD among Han Chinese.

  1. Bible Depicted in 2,000-year-old Han Dynasty Stone Carvings

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Wang Weifan is a member of the standing committee of the China Christian Council, and a Christian theology education professor. He recently discovered that several Eastern Han Dynasty museum exhibits in the Jiangsu Xuzhou Han Dynasty Stone Carving Museum include depictions of the bible and of early

  2. ¿A QUIÉN PERTENECE LA CULTURA? REFLEXIONES SOBRE UN BIEN COMÚN EN LA ECONOMÍA DEL CONOCIMIENTO

    OpenAIRE

    Molina Roldán, Ahtziri

    2013-01-01

    A lo largo de la historia, se han dado múltiples definiciones de lo que es cultura, las cuales están de acuerdo con las corrientes teóricas, el momento histórico en que aparecen y su lugar de origen. Por ello se han desarrollado tantas posturas teóricas ( hablar de) como marcos para la acción (hablar para) desde distintos podios de observación. Considero que en el contexto actual de globalización, donde el mercado es el principal móvil, es preciso inquirir sobre el valor de cambio que esta ca...

  3. Hans H. Ussing--scientific work: contemporary significance and perspectives.

    Science.gov (United States)

    Larsen, Erik Hviid

    2002-11-13

    As a zoologist, Hans H. Ussing began his scientific career by studying the marine plankton fauna in East Greenland. This brought him in contact with August Krogh at the time George de Hevesy, Niels Bohr and Krogh planned the application of artificial radioactive isotopes for studying the dynamic state of the living organism. Following his studies of protein turnover of body tissues with deuterium-labeled amino acids, Ussing initiated a new era of studies of transport across epithelial membranes. Theoretical difficulties in the interpretation of tracer fluxes resulted in novel concepts such as exchange diffusion, unidirectional fluxes, flux-ratio equation, and solvent drag. Combining methods of biophysics with radioactive isotope technology, Ussing introduced and defined the phrases 'short-circuit current', 'active transport pathway' and 'shunt pathway', and with frog skin as experimental model, he unambiguously proved active transport of sodium ions. Conceived in his electric circuit analogue of frog skin, Ussing associated transepithelial ion fluxes with the hitherto puzzling 'bioelectric potentials'. The two-membrane hypothesis of frog skin initiated the study of epithelial transport at the cellular level and raised new questions about cellular mechanisms of actions of hormones and drugs. His theoretical treatment of osmotic water fluxes versus fluxes of deuterium labeled water resulted in the discovery of epithelial water channels. His discovery of paracellular transport in frog skin bridged studies of high and low resistance epithelia and generalized the description of epithelial transport. He devoted the last decade of his scientific life to solute-coupled water transport. He introduced the sodium recirculation theory of isotonic transport, and in an experimental study, he obtained the evidence for recirculation of sodium ions in toad small intestine. In penetrating analyses of essential aspects of epithelial membrane transport, Ussing provided insights of

  4. DNM2 mutations in Chinese Han patients with centronuclear myopathy.

    Science.gov (United States)

    Lin, Pengfei; Liu, Xinhong; Zhao, Dandan; Dai, Tingjun; Wu, Huamin; Gong, Yaoqin; Yan, Chuanzhu

    2016-06-01

    Centronuclear myopathy (CNM) is a congenital myopathy characterized by an abnormally high number of muscle fibers with centrally located nuclei. Autosomal-dominant centronuclear myopathy-1 (CNM1) results from mutations in the dynamin 2 gene (DNM2) and accounts for approximately 50 % of all CNM cases. Up to now, around 35 mutations of DNM2 gene have been identified in CNM; however, the underlying molecular mechanism of DNM2 mutation in the pathology of CNM remains elusive, and the standard clinical characteristics and the genotype-phenotype correlation of DNM2 gene mutation with CNM have not yet been defined. Here, we report the clinical characteristics, molecular diagnosis strategy, and DNM2 gene mutations of four Chinese Han patients with CNM. Congenital myopathy-targeted next-generation sequencing (NGS) was applied to sequence the regions of the genome that contain all the coding regions of all known CNM genes and other congenital myopathy genes. We found potential DNM2 mutations in all four of the patients. Further targeted Sanger DNA sequencing of DNM2 found the 1106G>A (p.R369Q) mutation in patients 1 and 2, the c.1393C>T (p.R465W) mutation in patient 3, and the c.1565G>A (p.R522H) mutation in patient 4, all of which were reported previously to be causative mutations of DNM2-related CNM. Our results suggest that the combination of targeted NGS and Sanger sequencing is an effective, rapid, and reliable strategy for the molecular diagnosis of CNM and other genetically heterogeneous disorders. PMID:26908122

  5. En demonterbar konstruktion för utemiljö : med avstamp i Hans Johanssons formgivning

    OpenAIRE

    Johansson, Linda

    2011-01-01

    Jag fångades av enkelheten i inredningsarkitekten Hans Johanssons konstruktioner, flexibiliteten och den eleganta lättheten i hans möbler, de nätta dimensionerna och sättet han använder materialet trä. I mitt examensarbete undersöker jag möjligheten att vidareutveckla hans konstruktioner för att passa ett modernt liv på gränsen mellan ute och inne.Hans Johansson, som i år fyller nittio, började arbeta med sin idé om möbler konstruerade av ramar som ihopfogas utan skruv eller beslag för mer än...

  6. Estrategias de cumplimentación de pedidos en el sector de fabricación de bienes de equipo. Un estudio empírico

    OpenAIRE

    Sanchis Gisbert, Raquel; Saiz, Eduardo; Castellano, Eduardo; Poler Escoto, Raúl

    2011-01-01

    [ES] : El sector de bienes de equipo se caracteriza por fabricar productos complejos y con un alto grado de personalización. La elección de la estrategia de cumplimentación de pedidos que permita satisfacer de forma eficiente las necesidades específicas de sus clientes se convierte en una decisión estratégica de gran importancia. Como respuesta a esta demanda, el presente estudio analiza la relación entre diferentes estrategias de cumplimentación de pedidos (Ingeniería Bajo Pedido, Fabr...

  7. La Importancia del Grado de Intensidad de la Distribución en la Determinación del Valor de Marca de un Bien Duradero

    OpenAIRE

    Villarejo Ramos, Ángel Francisco

    2003-01-01

    En el presente trabajo pretendemos establecer una base teórica y empírica para la consideración de la influencia que ejerce el grado de intensidad con que es distribuido un bien duradero en la determinación del valor de marca de los mismos. Tras la revisión teórica que sustenta la posibilidad de aplicar técnicas de análisis basadas en los modelos de ecuaciones estructurales planteamos la confirmación empírica, en su caso, de las relaciones existentes entre la intensidad de la d...

  8. La doctrina de los bienes comunes de Francisco de Vitoria como fundamentación del dominio en el Nuevo Mundo

    OpenAIRE

    Añaños-Meza, M.C. (Mª Cecilia)

    2013-01-01

    En los últimos años se ha producido un renacimiento de la antigua idea de los bienes comunes como opción alternativa a las formas actuales de propiedad privada y pública, cuyos propulsores hacen referencia a su fuente más cierta, el derecho romano. Aunque es poco o nada conocido, esta idea fue empleada en el siglo XVI por el dominico español Francisco de Vitoria como una parte fundamental de su teoría del dominio que no sólo le va a servir para elaborar su análisis sob...

  9. AVANCES Y PERSPECTIVAS DEL DERECHO PARA LA RESTITUCIÓN DE BIENES CULTURALES A SUS PAÍSES DE ORIGEN EL CASO DEL PATRIMONIO CULTURAL

    OpenAIRE

    Antonio José Rengifo Lozano

    2008-01-01

    El debate sobre la restitución de bienes del patrimonio cultural, como una forma de reivindicación por coparte de los países de origen, se ha ido incrementando en la escena internacional y en el derecho publico, a favor de los procesos de constitucionalizacion de la cultura en el mundo, como ha sido el caso de la constitución política de Colombia de 1.991 de la adopción de tratados internacionales y del rol eficaz del comité intergubernamental de la UNESCO, como organismo internacional instit...

  10. Avances y perspectivas del derecho para la restitución de bienes culturales a sus países de origen: el caso del patrimonio cultural quimbaya

    OpenAIRE

    Rengifo Lozano, Antonio José

    2013-01-01

    Con base en el estudio comparado de los casos de restitución de los Mármoles del Partenón, promovido por Grecia y del Patrimonio Cultural Quimbaya en Colombia, el presente artículo sustenta la tesis de que aunque el derecho para la restitución de bienes culturales se encuentra en etapa inicial de consolidación y, por tanto, de seguro tendrá muchos desarrollos en el futuro, existen en la actualidad bases jurídicas suficientes para hacer efectiva esa restitución, necesaria para realizar el l...

  11. Perspectivas del crecimiento urbano: la actividad comercial minorista y el transporte de bienes en la Zona Metropolitana de Querétaro (México)

    OpenAIRE

    Eduardo Betanzo-Quezada

    2015-01-01

    Se muestran las perspectivas del crecimiento urbano, la actividad comercial minorista y su relación transversal con el transporte de bienes en la Zona Metropolitana de Querétaro (México). Con una metodología de análisis de información estadística de tipo agregado, se examinan esos determinantes con el objetivo de revelar sus tendencias en la ciudad. El paralelismo encontrado en las tendencias de comportamiento de los determinantes examinados conduce a concluir que es cada vez más necesario co...

  12. Los bienes de capital en el Programa de Cooperación e Integración Argentina-Brasil : 1986-1989

    OpenAIRE

    Luchetti, Javier Fernando

    2005-01-01

    El MERCOSUR es constituido como una continuidad del Programa de Integración y Cooperación entre Argentina y Brasil, si bien abandona sus principios fundamentales, cambiando sensiblemente su diseño global y el modelo de integración subyacente. El PICAB se proponía crear un espacio económico común para mejorar el bienestar de los pueblos, mediante una complementación de sectores de las economías de ambos países, según los principios de gradualismo, flexibilidad, selectividad, equilibrio, profun...

  13. La respuesta a la vocación al bien común de las empresas cotizadas en la bolsa mexicana de valores

    OpenAIRE

    Reyes-Sahagun, C. A. (Carlos Antonio); Dembinski, P. (Paul)

    2016-01-01

    Las decisiones en la empresa moderna tienen influencia de ideas académicas que ponen énfasis en la máxima eficiencia para generar beneficios económicos en favor del accionista y en los acuerdos contractuales entre las diversas partes interesadas. En esta tesis se investiga cómo estos dos aspectos pueden enriquecerse con el estudio del concepto de bien común de la tradición aristotélico-tomista y de la Doctrina Social de la Iglesia. Estas ideas proporcionan una visión más amplia...

  14. Reestimación del grado de transmisión de la tasa de cambio del peso sobre la inflación de los bienes importados

    OpenAIRE

    2014-01-01

    Conocer el grado de transmisión de los cambios en la tasa de cambio sobre la inflación interna es un interrogante constante de las autoridades monetarias de cualquier país. En este documento se reestima el grado de transmisión de corto y mediano plazo de las variaciones de la tasa de cambio del peso colombiano sobre la inflación de los bienes importados, estimados en González et al. (2010). Se utilizan datos trimestrales de Colombia para el período 1985-2014 y un modelo VAR no lineal de trans...

  15. La casa y el ajuar de la familia Coronel a través de un inventario de bienes del siglo XVI

    Directory of Open Access Journals (Sweden)

    De la Peña Barroso, Efrén

    2015-12-01

    Full Text Available In the last years we have been working on the person of don Abraham Seneor/Fernán Pérez Coronel and his offspring, mainly from his son Íñigo López Coronel. In this occasion we will focus on the structure of the dwelling house and the household goods of the family through an inventory made in Segovia in 1522. This document will allow us to know the wealth level, the shy investment in luxury goods and the list of part of the household goods of this important family of Segovian conversos.Desde hace ya varios años estamos trabajando en la figura de don Abraham Seneor/Fernán Pérez Coronel y su descendencia, sobre todo por la vía de su hijo Íñigo López Coronel. En esta ocasión, estudiaremos la estructura espacial de su casa, sus bienes muebles y el ajuar de esta rama familiar a través de un inventario de bienes realizado en sus «casas principales» de la ciudad de Segovia en el año 1522. Este inventario nos permitirá acercarnos a los niveles de riqueza, a la escasa inversión en productos de lujo y al conocimiento de gran parte del ajuar de esta importante familia de judeoconversos segovianos.

  16. La repercusión del valor razonable de los bienes inmuebles en la utilidad de los estados financieros: una nota de investigación

    Directory of Open Access Journals (Sweden)

    Andrés Navarro Galera

    2009-01-01

    Full Text Available La elección en la reciente reforma contable española del criterio de valor razonable en lugar del coste histórico como base de valoración para determinados activos ha generado cierta controversia. Este trabajo estudia la posible incidencia de la adopción del valor razonable para el registro contable de los bienes inmuebles sobre la relevancia y la fiabilidad de la información financiera. El estudio empírico está basado en una encuesta sobre las percepciones de 151 responsables de la contabilidad de empresas españolas del sector de la construcción sobre la utilidad y fiabilidad de la información financiera basada en el valor razonable. El análisis de los resultados nos ha permitido concluir que, respecto al coste histórico, los responsables de contabilidad perciben que el valor razonable de los bienes inmuebles generaría estados financieros más útiles para representar la imagen fiel del patrimonio de la empresa. No obstante, los encuestados conciben la información financiera bajo valor razonable como menos objetiva y verificable. Asimismo, hemos comprobado que el tamaño de la empresa puede influir en la opinión de la repercusión del valor razonable sobre la relevancia y fiabilidad de los estados financieros.

  17. Gasto particularista en bienes públicos locales: índice de desviación Particularistic expenditure on local public goods: an index of deviation

    Directory of Open Access Journals (Sweden)

    María Alejandra Armesto

    2012-09-01

    Full Text Available El gasto particularista del gobierno se opone al gasto programático. Los dos tipos de medidas clasifican los beneficios de políticas como particularistas si son bienes exclusivos o si son explicados por variables políticas. Este artículo desarrolla un índice de gasto particularista en bienes públicos locales medido como desviación con respecto al programa. Se aplica el índice a la oferta de servicios básicos por administraciones subnacionales seleccionadas en México y Argentina. Se muestra que el índice corre menos riesgos de sobreestimar o subestimar el gasto particularista y el gasto programático que las medidas existentes.This article compares particularistic and programmed government spending. The two types of measures classify the benefits of policies as particularistic if they are exclusive goods or if they are determined by political variables. This article contains an index of particularistic expenditure on local public goods, measured as a deviation from the program. It applies this index to the supply of basic services from selected sub-national administrations in Mexico and Argentina. It shows that this index is less likely to over- or under-estimate particularistic and programmatic expenditure than existing measures.

  18. L’addiction ou les addictions ; en quête d'un bien-être et pathologie de système ?

    Directory of Open Access Journals (Sweden)

    Thierry Jandrok

    2016-04-01

    Full Text Available Dans le cadre de cet article nous reviendrons sur le sens du terme d’«addiction» qui remplaça, il y a quelques années, celui de «toxicomanie». De nos jours, le discours politiquement correct ne stigmatise plus. Il ne présente plus, n’accuse plus. Il culpabilise et met l'accent sur la fonction consommatrice et la relation d’un individu aux pratiques et aux productions des plaisirs. On parle désormais d'usager, de consommateur. Ce personnage décrit par la vulgate contemporaine est distinctement inclus dans le système marchand des biens et des services. Que cachent ces arguties lexicales ? Quelle est le sens de cette démarche économico-politique qui privilégie la fonction sur le sujet ? Quel est donc ce clivage dans la définition de pratiques qui, bien que collectives, n'en restent pas moins singulières et, par conséquent, inaliénables ? L'addiction n'existe pas sans un référentiel théorique, politique et économique, sans un background à partir duquel certains sens se créent et s'échangent. Dans ce mouvement, l’addiction tend à s’effacer, en même temps que la subjectivité, derrière une brume sémantique qui hésite entre la stigmatisation de pratiques pathologiques singulières et comportements transgressifs, apparemment détachés des échanges. Dans ce cadre, nous interrogerons ces théories qui du semblant et de l’apparence proposent un sens à une fonction au détriment de ceux qui pourraient l’habiter ? Comment le sujet est-il déshabillé de sa consistance, de ses souffrances, de sa jouissance, et finalement de sa quête de bien-être ou de mal-être, au profit de discours qui n’entendent que l’enchaînement des actes comme preuves de qui il serait ? Le retrait de la composante maladive de l’addiction a dénaturé sa réalité. Sans la notion de mal ou le concept de maladie, comment faire valoir le bien et par conséquent redonner sens à la notion de «bien-être» ? Les lumières des discours

  19. Rootsi ja Eesti - kümme aastat koostööd / Hans Lepp

    Index Scriptorium Estoniae

    Lepp, Hans, 1950-

    2003-01-01

    Rootsi Instituudi kultuuri- ja ühiskonnaosakonna direktor Hans Lepp meenutab oma tegevust Rootsi kultuuriatašeena Eestis 1990ndatel aastatel. Ka autori meenutused kohtumisest RRi peadirektori Ivi Eenmaaga, ka rootsi saali asutamisest RRis

  20. The changes of plasma adrenomedullin level in Han and tibetan health adult men in plateau area

    International Nuclear Information System (INIS)

    To investigate the changes and clinical significance of plasma adrenomedullin in Han and Tibetan health adult men at the state of chronic hypoxia. The Han health adult who migrated and lived above sea level 4200 meter for 1∼3 years and the native Tibetan were involved in this study. The plasma adrenomedullin levels in both Han and Tibetan health adult men were measured by RIA. The results showed that the plasma adrenomedullin levels of native Tibetan were significantly higher than that of migrated Han worker (P<0.05). The plasma adrenomedullin might play a regulatory role on the physiological function in the health adult men who live in high altitude hypoxic state. (authors)

  1. La opacidad de los acuerdos generales de bienes y servicios en España Opacity of general agreements on goods and services in Spain

    Directory of Open Access Journals (Sweden)

    Román Andrés Umaña Peña

    2006-06-01

    Full Text Available Objetivo: Explorar la intensidad del debate parlamentario sobre el Acuerdo General de Comercio de Servicios (AGCS asumido por España ante la Organización Mundial del Comercio (OMC, y compararla con la del Acuerdo General de Bienes (GATT. Métodos: Búsqueda sistemática y análisis del contenido de todas las iniciativas parlamentarias sobre AGCS y GATT realizadas entre 1979 y 2004 en el Congreso de los Diputados y el Senado. Se calculó la frecuencia y porcentaje de iniciativas parlamentarias de ambos temas, resultado de su tramitación y tipo de iniciativa. Resultados: Se presentaron 185 iniciativas parlamentarias sobre los acuerdos multilaterales de bienes y servicios, de las que 120 se referían al GATT, 8 al AGCS y 57 a ambos acuerdos. La mayoría de las iniciativas no fueron discutidas (GATT, 71%; GATS, 55,4% o estuvieron sujetas a un debate político en el que apenas se dieron intervenciones por parte de los grupos parlamentarios. Conclusiones: A pesar de las implicaciones del acuerdo multilateral de servicios para la política sanitaria española, éste se ha asumido con escaso debate parlamentario previo, incluso menos que en el caso de su homólogo sobre bienes. Se requiere en este tema una intensificación de la función de control al gobierno.Objective: To explore the intensity of the debate in the Spanish Parliament on the General Agreement on Trade in Services (GATS developed by Spain and the World Trade Organization, and to compare it with the debate on the General Agreement on Tariffs and Trade (GATT. Methods: A systematic search and content analysis were performed of all parliamentary initiatives on GATS and GATT undertaken from 1979 to 2004 in the Spanish Parliament and Senate. The frequency and percentages of initiatives on both issues were calculated, and the final result and kinds of initiative were analyzed. Results: A total of 185 initiatives were presented in the Spanish Parliament on these agreements, of which 120 were

  2. Producción y percepción de bienes públicos en la lógica de la acción colectiva

    Directory of Open Access Journals (Sweden)

    Jordana, Jacint

    2007-04-01

    Full Text Available Public goods having different proprieties produce different problems of collective action. This hypothesis has been discussed from different analytical perspectives and we examine their arguments, aiming to deepen our theoretical understanding about the logic of collective action. In this paper we look for similarities and differences regarding their use of concepts and expected results. Simultaneously, we examine the link between different public goods and the interdependent behavior of individuals. To this purpose, we also revisit the connections between production functions and consumption types in the case of public goods, as a mean to explore the potential development of more elaborated models in the theory of collective action, and suggest that more empirical contrast of these models is needed. Finally, we argue the importance for theoretical discussions to include a discussion about the impact of perception in the collective action models, considering systematic deviations to rational choice, and conclude that no single theory may address all collective action problems, but systematic patterns of behavior may be identified and empirically confirmed.

    Bienes públicos con distintas propiedades generan problemas diferentes de acción colectiva. Esta hipótesis ha sido discutida, desde distintas perspectivas analíticas, con el objeto de profundizar teóricamente sobre la lógica de la acción colectiva. En este trabajo se revisan las aportaciones recientes a esta cuestión, analizando sus puntos de encuentro y sus divergencias en cuanto a conceptos y resultados esperados. Asimismo, se examina la relación entre tipos distintos de bienes públicos y el comportamiento interdependiente de los individuos. Con este fin, los vínculos entre las funciones de producción y las formas de consumo de bienes públicos también son considerados, ya que permite desarrollar modelos más ambiciosos sobre la lógica de la acción colectiva. Finalmente

  3. Tallinna linnaelu kajastumine raehärra Hans Rotgersi märkmetes / Tiina Kala

    Index Scriptorium Estoniae

    Kala, Tiina

    2008-01-01

    Hans Rotgersi aktiivne tegutsemisperiood hõlmab 15. sajandi viimase ja 16. saj. esimese veerandi. Kõige ulatuslikuma kirjaliku pärandi on ta endast maha jätnud Niguliste kiriku eestseisjana. Niguliste kiriku olulistest daatumitest. Maksujõuliste tallinlaste surma kajastumisest Rotgersi ülestähendustes. Rotgersi käsikirjas säilinud astroloogiliste ja meditsiiniliste soovituste kogust. Hans Rotgersi testamendist.

  4. Porcelain in the Ming Dynasty:Cultural and Artistic Exchanges Between Hans and Tibetans

    Institute of Scientific and Technical Information of China (English)

    WuMingdi

    2004-01-01

    As an example of Chinese arts and crafts, porcelain is an important element of Chinese culture. In ancient times, when transport and communications were extremely backward, the continuous flow of porcelain items between Han Chinese and Tibetans played an essential role in their material and cultural life. Put specifically, the close relationship between porcelain and Han-Tibetan cultural and artistic exchanges can be observed as follows:

  5. Microbial community development on the surface of Hans and Werenskiold Glaciers (Svalbard, Arctic): a comparison

    OpenAIRE

    Grzesiak, Jakub; Górniak, Dorota; Świątecki, Aleksander; Aleksandrzak-Piekarczyk, Tamara; Szatraj, Katarzyna; Zdanowski, Marek K.

    2015-01-01

    Surface ice and cryoconite holes of two types of polythermal Svalbard Glaciers (Hans Glacier—grounded tidewater glacier and Werenskiold Glacier—land-based valley glacier) were investigated in terms of chemical composition, microbial abundance and diversity. Gathered data served to describe supraglacial habitats and to compare microbe–environment interactions on those different type glaciers. Hans Glacier samples displayed elevated nutrient levels (DOC, nitrogen and seston) compared to Werensk...

  6. Prevalence of Diabetes and Associated Factors in the Uyghur and Han Population in Xinjiang, China

    OpenAIRE

    Haiying Gong; Lize Pa; Ke Wang; Hebuli Mu; Fen Dong; Shengjiang Ya; Guodong Xu; Ning Tao; Li Pan; Bin Wang(Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240, China); Guangliang Shan

    2015-01-01

    Objective: To estimate the prevalence of diabetes and identify risk factors in the Uyghur and Han population in Xinjiang, China. Methods: A cross-sectional study in urban and rural areas in Xinjiang, including 2863 members of the Uyghur population and 3060 of the Han population aged 20 to 80 years, was conducted from June 2013 to August 2013. Data on fasting plasma glucose (FPG) and personal history of diabetes were used to estimate the prevalence of diabetes. Data on demographic characterist...

  7. Paul and Hans Vredeman de Vries, the Five Senses, and the five architectural orders

    Czech Academy of Sciences Publication Activity Database

    Konečný, Lubomír

    Marburg : Jonas Verlag, 2005 - (Borggrefe, H.; Lüpkes, V.), s. 152-160 ISBN 3-89445-334-6. - (Studien zur Kultur der Renaissance. 3). [Hans Vredeman de Vries und die Folgen. Lemgo (DE), 30.01.2004-01.02.2004] Institutional research plan: CEZ:AV0Z80330511 Keywords : Paul and Hans Vredeman de Vries * Five Senses * five architectural orders Subject RIV: AL - Art, Architecture, Cultural Heritage

  8. The application of Han Dynasty cultural elements to modern product design

    OpenAIRE

    Chen, L.; KANG, J; Zhang, L.; Wang, M.; Wang, D

    2014-01-01

    Chinese Han Culture, as Chinese nation's "core culture", is the cultural symbol of Chinese nation, and played an important role in the history of Chinese cultural development, even in the history of world cultural development. Designing in the Han Dynasty, while inheriting Chinese traditional culture, but also having its unique style, are appreciated and respected by the people nowadays. In a modern society where the design is becoming more diversified, the innovative design based on traditio...

  9. Minu moto : alati kõrgustesse! Dr. Hans O. A. Koehn, ADDINOL Lube Oil GmbH osanik - 80 / Hans O. A. Koehn ; interv. Mikk Mehide

    Index Scriptorium Estoniae

    Koehn, Hans O. A.

    2006-01-01

    Maailma tippkvaliteediga määrdeaineid tootva Saksa õlifirma Addinol osanik dr. Hans O. A. Koehn on üks juhtivaid isikuid Saksamaa mineraalõli majanduses, tööst õlifirmas Valvoline, edasisest karjäärist ning Addinoli osanikuks saamisest

  10. Plant crop remains from the outer burial pit of the Han Yangling Mausoleum and their significance to Early Western Han agriculture

    Institute of Scientific and Technical Information of China (English)

    YANG XiaoYan; LIU ChangJiang; ZHANG JianPing; YANG WuZhan; ZHANG XiaoHu; L(U) HouYuan

    2009-01-01

    A large amount of carbonized plant remains were discovered in one of the outer burial pits of the Han Yangling Mausoleum, which was built more than 2000 years ago for the Jing Emperor, Liu, Qi (188-141 cal a BC), the fourth emperor of the Western Han Dynasty. The remains are identified by phytolith analysis and macrofossil morphological features. Seeds from foxtail millet (Setaria italica), broomcorn millet (Panicum miliaceum), rice (Oryza sativa) and chenopod (possible Chenopodium giganteum) are identified, suggesting that these four crops might have been the staple plant foods in the capital area (Guanzhong area), Shaanxi Province during the Early Western Han Dynasty. Chenopods were often considered as weeds since they have only been rarely found as carbonized seeds in prehistoric sites. This is the first time such a large amount of seeds has been found at a site, which provides strong material evidence for chenopod cultivation with a long history in China. Wheat was thought to be promoted and popularized in the Guanzhong area since the Wu Emporor, Liu, Che (156-87 cal a BC), the fifth emperor of the Western Han Dynasty. No wheat was found at this site, which supports the historical document record that wheat was still secondary in the diet and agrarian economy before the Wu Emperor's reign.

  11. An Unknown Tradition of Han Chinese Conversions to Tibetan Buddhism:Han Chinese Incarnate Lamas and Parishioners of Tibetan Buddhist Monasteries in Amdo

    Institute of Scientific and Technical Information of China (English)

    Gray Tuttle

    2013-01-01

    AbstrActThis article examines Han Chinese who has historically practiced Tibetan Buddhism in the Qinghai-Gansu border region. The main primary sources were published in the 1990s, based on surveys by Chinese social scientists who were sent around in the 1950s to collect data on Tibetan Buddhist institutions as well as additional independent surveys from the 1980s and my own site visits in 2006. On the basis of these sources, I argue that there are at least 100,000 and probably as many as 200,000 Han Chinese on the borders of Qinghai and Gansu (part of the Amdo cultural region for Tibetans) practicing Tibetan Buddhism, following traditions that seem to have been in place for centuries. I also discuss the sixteen historic cases of Han Chinese reincarnate lamas and the over one hundred monasteries in this region affiliated with Han Chinese. Finally, I note the sectarian affiliations (jiaopai: Nyingma, Geluk, etc.) and religious practices of these Chinese communities practicing Tibetan Buddhism.

  12. El Puerto de La Laja (Huelva, como Bien de Interés Cultural en la categoría de Sitio Histórico

    Directory of Open Access Journals (Sweden)

    Emilio Romero Macías

    2010-01-01

    de sol y playa para el conocimiento de otras culturas y como plan dinamizador de zonas que han sido afectadas por el declive de la minería en nuestra provincia. Parte del poblado del Puerto de La Laja se encuentra actualmente rehabilitado para su explotación como turismo rural, por lo que la arquitectura en cierto modo ha tratado de conjuntar la antigua disposición de las casas con las mejoras realizadas para este tipo de uso.

  13. L’évocation des biens communs dans les revendications citoyennes contre le gaz de schiste au Québec

    OpenAIRE

    Goupil, Sylvie

    2016-01-01

    Le présent article s’interroge sur l’action citoyenne et plus particulièrement sur ce qui peut pousser des personnes, qui ont toujours vécu dans un « anonymat politique », à se lancer dans une action publique qui interpelle les gouvernements. L’auteure prend pour point de départ la conception selon laquelle des préoccupations vécues dans la vie quotidienne sont à l’origine d’une prise de conscience quant à un problème qui concerne ce que les acteurs identifient comme des biens communs. Elle i...

  14. Les représentations de l’animal et du bien-être animal par les éleveurs français

    OpenAIRE

    Dockes, Anne-Charlotte; Kling-Eveillard, Florence

    2007-01-01

    Plusieurs travaux récents ont permis d’appréhender les représentations des éleveurs, vis-à-vis de l’animal et du bien-être animal. Ils mettent en évidence un certain nombre d’éléments communs à tous les éleveurs : la place centrale de l’animal dans la définition du métier, la relation professionnelle aux animaux, le rôle central de l’observation dans le métier d’éleveur… Ils montrent la diversité des représentations de l’élevage, des animaux d’élevage et des pratiques, en fonction du type d’a...

  15. Les caractéristiques du climat forestier et son influence sur le bien-être: le cas de l'été 2003 en Suisse

    OpenAIRE

    Läderach, Sabina; Rebetez, Martine

    2007-01-01

    Les dernières décennies ont été caractérisées par le dépassement régulier du record des périodes les plus chaudes depuis le début de l’enregistrement des mesures météorologiques et il devient de plus en plus clair que nous devrons apprendre à faire face à des situations de canicule de plus en plus fréquentes. Est-ce que la forêt peut jouer un rôle favorable pour notre bien-être dans ce contexte? L’enjeu de ce mémoire est de répondre à cette question. Cela dans un premier temps en comparant le...

  16. Perspectivas del crecimiento urbano: la actividad comercial minorista y el transporte de bienes en la Zona Metropolitana de Querétaro (México

    Directory of Open Access Journals (Sweden)

    Eduardo Betanzo-Quezada

    2015-01-01

    Full Text Available Se muestran las perspectivas del crecimiento urbano, la actividad comercial minorista y su relación transversal con el transporte de bienes en la Zona Metropolitana de Querétaro (México. Con una metodología de análisis de información estadística de tipo agregado, se examinan esos determinantes con el objetivo de revelar sus tendencias en la ciudad. El paralelismo encontrado en las tendencias de comportamiento de los determinantes examinados conduce a concluir que es cada vez más necesario conectar al transporte urbano de carga con la planeación económica y urbana, y ubicarlo dentro de las prioridades de las administraciones gubernamentales.

  17. Prevalence of Diabetes and Associated Factors in the Uyghur and Han Population in Xinjiang, China

    Directory of Open Access Journals (Sweden)

    Haiying Gong

    2015-10-01

    Full Text Available Objective: To estimate the prevalence of diabetes and identify risk factors in the Uyghur and Han population in Xinjiang, China. Methods: A cross-sectional study in urban and rural areas in Xinjiang, including 2863 members of the Uyghur population and 3060 of the Han population aged 20 to 80 years, was conducted from June 2013 to August 2013. Data on fasting plasma glucose (FPG and personal history of diabetes were used to estimate the prevalence of diabetes. Data on demographic characteristics, lifestyle risk factors, and lipid profiles were collected to identify risks factors using the multivariate logistic regression model. Results: In urban areas, the age- and gender-standardized prevalence of diabetes was 8.21%, and the age- and gender-standardized prevalence of diabetes was higher in the Uyghur population (10.47% than in the Han population (7.36%. In rural areas, the age- and gender-standardized prevalence of diabetes was 6.08%, and it did not differ significantly between the Uyghur population (5.71% and the Han population (6.59%. The results of the multivariate logistic regression analysis showed that older age, obesity, high triglycerides (TG, and hypertension were all associated with an increased risk of diabetes in the Uyghur and Han population. Urban residence and low high-density lipoprotein cholesterol (HDL-C were associated with an increased risk of diabetes in the Uyghur population. Being an ex-drinker was associated with an increased risk of diabetes and heavy physical activity was associated with a decreased risk of diabetes in the Han population. Conclusions: Our study indicates that diabetes is more prevalent in the Uyghur population compared with the Han population in urban areas. Strategies aimed at the prevention of diabetes require ethnic targeting.

  18. Prevalence of Diabetes and Associated Factors in the Uyghur and Han Population in Xinjiang, China

    Science.gov (United States)

    Gong, Haiying; Pa, Lize; Wang, Ke; Mu, Hebuli; Dong, Fen; Ya, Shengjiang; Xu, Guodong; Tao, Ning; Pan, Li; Wang, Bin; Shan, Guangliang

    2015-01-01

    Objective: To estimate the prevalence of diabetes and identify risk factors in the Uyghur and Han population in Xinjiang, China. Methods: A cross-sectional study in urban and rural areas in Xinjiang, including 2863 members of the Uyghur population and 3060 of the Han population aged 20 to 80 years, was conducted from June 2013 to August 2013. Data on fasting plasma glucose (FPG) and personal history of diabetes were used to estimate the prevalence of diabetes. Data on demographic characteristics, lifestyle risk factors, and lipid profiles were collected to identify risks factors using the multivariate logistic regression model. Results: In urban areas, the age- and gender-standardized prevalence of diabetes was 8.21%, and the age- and gender-standardized prevalence of diabetes was higher in the Uyghur population (10.47%) than in the Han population (7.36%). In rural areas, the age- and gender-standardized prevalence of diabetes was 6.08%, and it did not differ significantly between the Uyghur population (5.71%) and the Han population (6.59%). The results of the multivariate logistic regression analysis showed that older age, obesity, high triglycerides (TG), and hypertension were all associated with an increased risk of diabetes in the Uyghur and Han population. Urban residence and low high-density lipoprotein cholesterol (HDL-C) were associated with an increased risk of diabetes in the Uyghur population. Being an ex-drinker was associated with an increased risk of diabetes and heavy physical activity was associated with a decreased risk of diabetes in the Han population. Conclusions: Our study indicates that diabetes is more prevalent in the Uyghur population compared with the Han population in urban areas. Strategies aimed at the prevention of diabetes require ethnic targeting. PMID:26473908

  19. ¿qué papel juega la definición de la eudaimonía en la concepción del bien humano de aristóteles?

    OpenAIRE

    Velásquez, Beatríz Alejandra

    2012-01-01

    Aristóteles propone una concepción del bien humano que determina (hasta con un cierto grado de precisión) cómo hemos de ser, actuar y en general vivir. Tal concepción se logra, según él, definiendo el bien humano, y en EN 1.7 lo define como “una actividad del alma según la virtud”. Esta definición no brinda información acerca de cómo ser y actuar, por lo que parece no contener la concepción esperada del bien, lo cual sí logra la teoría de la virtud presentada en libros posteriores. ¿Qué papel...

  20. Attachment and sibling rivalry in Little Hans: the fantasy of the two giraffes revisited.

    Science.gov (United States)

    Wakefield, Jerome C

    2007-01-01

    Freud's interpretation of Little Hans's "phantasy of the two giraffes" is pivotal to his oedipal analysis that Hans has inchoate desires for sexual intercourse with his mother. Bowlby argued that Freud's focus on his oedipal theory led him to ignore preoedipal attachment-related factors that have equal plausibility in explaining the clinical data. However, Bowlby did not attempt to apply the attachment perspective to the interpretation of Hans's fantasies that form the core of the case material. A microanalysis of Hans's giraffe fantasy and the evidence used to support Freud's claims about it yields an attachment-based sibling rivalry account arguably of greater explanatory power than the oedipal account. Consistent with Bowlby's hypothesis, the evidence suggests that Hans's giraffe fantasy is about the sibling rivalry triangle involved in caregiver attachment access, rather than (or in addition to) the oedipal triangle. The issue of multiple levels of meaning and the methodological challenges raised by multiple determination is also considered. The giraffe fantasy's attachment-theoretic explanation encourages a rethinking of this classic case and strengthens Bowlby's claim that the case is fruitfully viewed from an attachment perspective. PMID:17915649

  1. FACTORES DE ÉXITO EN PROVEEDORES DE BIENES MANUFACTURADOS DE LA SALMONICULTURA CHILENA SUCCESS FACTORS IN SUPPLIERS OF MANUFACTURES WITHIN THE CHILEAN SALMON INDUSTRY

    OpenAIRE

    Carlos Torres Fuchslocher; Hanns de la Fuente Mella

    2009-01-01

    Este artículo analiza, en base a un trabajo empírico, los principales factores a nivel de la empresa que han determinado el éxito de los proveedores locales de manufacturas, en términos de participación de mercado, en el cluster del salmón en Chile. La investigación envolvió un levantamiento de material empírico a través de 50 entrevistas, las cuales fueron evaluadas cualitativamente y por medio de un análisis econométrico de corte transversal, usando variables explicativas cualitativas. Los ...

  2. Som i et spejl - Hans Egede-receptionen gennem tre hundrede år

    DEFF Research Database (Denmark)

    Kjærgaard, Kathrine

    2008-01-01

    Erik Pauelsen - hang i tusindvis af hjem og blev i årene omkring 1800 et af de mest udbredte og elskede billeder i Danmark-Norge. For Hans Egede-receptionen blev opløsningen af den dansk-norske union ved freden i Kiel januar 1814 skæbnesvanger. I Norge var vreden over at Grønland var gået til Danmark...... tilbageholdende med at omklamre tidligere norske landsmænd som Hans Egede. Først hen mod slutningen af 1800-tallet begyndte forbeholdene at smelte et efter et. Den definitive omdefinering af den dansk-norske 1700-tals patriot til national dansk kirkefyrste kom med opstillingen 1913 af hans statue ved Marmorkirken...

  3. Comprehensive cortical thickness and surface area comparison between young Uyghur and Han Chinese cohorts.

    Science.gov (United States)

    Lu, Jun; Jiang, Chunhui; Wang, Jian; Jia, Wenxiao

    2016-10-01

    We hypothesized that the brain structural differences as discovered previously between Westerners and East Asians could also be revealed between Han Chinese and Uyghur, which were genetically related ethnic groups with distinct languages. We conducted a brain MRI structural comparison in terms of cortical thickness and surface area between 15 healthy young Uyghurs and 15 age-matched Han Chinese. Widespread regions with significantly greater cortical thickness were found in the Uyghurs, and their distribution showed strong resemblance to previous "Westerners vs. Asians" findings. While surface area analysis displayed less widespread brain differences. Notably, our detected regions with structural differences contained a large part of language-specific or at least closely language-related brain areas, which may partly be attributable to the brain plasticity respectively driven by Uyghur and Mandarin. Our findings will help to better understand the neurobiological basis of interethnic differences along with the language processing mechanisms of Han Chinese and Uyghur. PMID:27067474

  4. La Repercusión del Valor Razonable de los Bienes Inmuebles en la Utilidad de los Estados Financieros: Una Nota de Investigación

    Directory of Open Access Journals (Sweden)

    Andrés Navarro Galera

    2009-06-01

    Full Text Available La elección en la reciente reforma contable española del criterio de valor razonable en lugar del coste histórico como base de valoración para determinados activos ha generado cierta controversia. Este trabajo estudia la posible incidencia de la adopción del valor razonable para el registro contable de los bienes inmuebles sobre la relevancia y la fiabilidad de la información financiera. El estudio empírico está basado en una encuesta sobre las percepciones de 151 responsables de la contabilidad de empresas españolas del sector de la construcción sobre la utilidad y fiabilidad de la información financiera basada en el valor razonable. El análisis de los resultados nos ha permitido concluir que, respecto al coste histórico, los responsables de contabilidad perciben que el valor razonable de los bienes inmuebles generaría estados financieros más útiles para representar la imagen fiel del patrimonio de la empresa. No obstante, los encuestados conciben la información financiera bajo valor razonable como menos objetiva y verificable. Asimismo, hemos comprobado que el tamaño de la empresa puede influir en la opinión de la repercusión del valor razonable sobre la relevancia y fiabilidad de los estados financieros.The option in the recent Spanish regulation for fair value over historical cost, as the preferred measurement basis for some assets, has raised some controversy. This paper studies the effects on accounting information relevance and reliability of fair value accounting for investment properties. The empirical study is based on a questionnairebased survey of the perceptions of 151 Spanish accountants in the building industry about the usefulness and reliability of fair value accounting. The analysis of results allows us concluding that accountants perceive that the usefulness of financial statements increases when investment property is valued on a fair value basis, compared with a historical cost basis. However, respondents

  5. Relation of Plasma Uric Acid Levels and the Lipid Parameters in Han and Uygur Ethnicity

    Institute of Scientific and Technical Information of China (English)

    Sun Yuping; Yao Hua; Yao Wenhai; Li Qing; You Lan; Wang Qiuyun; Jiang Yan

    2006-01-01

    Objectives Hyperuricemia is a common finding in hypertension and hyperlipidemia,they are all correlated to cardiovascular diseases. The aim of this study was to find the relationship of uric acid and plasma lipid parameters of Han and Uygur ethnicity in Xinjiang. Methods This cross-sectional health examination survey was based on a population random sample from the Urumchi, It included 1166 subjects aged from 20 to 70 years. Serum biochemical testing by Automatic Analyzer (HITACHI 7600-010).Results The uric acid in Han was higher than in Uygur(P< 0.05), men were higher than women in two ethnicities; For lipid parameters men were higher than women, in TG and HDL women were higher than in men in two ethnicity (P < 0.05). Serum uric acid was strongly related to serum triglycerides in Han as well as Uygur ethnicity ( P < 0.001); Compared with the normal group, UA, TG, CHOL, VLDL had ascending trend and HDL had descending trend (P <0.05 ) among groups in Han and Uygur ethnicity,especially Hyperuricemia-hypertriglyceridemia group,uric acid and most some lipid parameters was higher than Hyperuricemia and hypertriglyceridemia group,The prevalence of different groups in Han and Urgur was significantly different (P < 0.05). Conclusions This study shows that the UA and some lipid parameters are different in Han and Uygur ethnicity and show sexual difference; serum uric acid is markedly related to serum triglycerides; Hyperuricemia and hypertriglyceridemia show cooperated effect in uric acid and most lipid parameters. Considering the growing incidence of the potential link between hyperuricemia/hypertriglyceridemia and cardiovascular diseases, more emphasis should be put on the evolving prevalence of hyperuricemia and hypertriglyceridemia in Xinjiang.

  6. The Religious And Political Attitude Of Abû Hanîfa

    OpenAIRE

    DOĞAN, İsa

    2006-01-01

    The relapsing of the tribal manners after the Prophet’s death prevented that political system supported with scientific criterions. This situation caused of the chaos to be lived in Islamic society. Abû Hanîfa even was one of the men suffering annoyances of wrong politics. Racist Umayyad didn’t act with fairness towards Mavali new rightly guided in social, economic, and religious subjects. This situation caused Abû Hanîfa to be directed towards defensing the political and the legal rights of...

  7. Using poetry to develop teenagers' speaking competence at Han-Mei Language Institute in Taiwan

    OpenAIRE

    Lee, Hui-Chun

    2003-01-01

    English teaching in Taiwan is usually teacher-centred and test-oriented, especially at a private sector school like Han-Mei Language Institute which functions to ‘teach to the test’ (Brown, 1995) and trains teenage students to pass various exams for academic purposes. The exam backwash, however, has led to the imbalance of focusing on students’ linguistic abilities but neglecting their speaking competence. In addition, at Han-Mei, the required textbook, Reference Book—English in detail for ju...

  8. Debating Modernity as Secular Religion: Hans Kelsen’s futile exchange with Eric Voegelin

    DEFF Research Database (Denmark)

    Thomassen, Bjørn

    2014-01-01

    This article reviews the mysterious and recently published last book by Hans Kelsen, “Secular Religion. A Polemic Against the Misinterpretation of Modern Social Philosophy, Science and Politics as ‘New Religions’”, contextualizing it with reference to the little known dialogue between Hans Kelsen....../secularity debate, the positivist/anti-positivist debates, and the controversy that also led to the famous Voegelin/Arendt debate: how to read the horrors of totalitarianism into a historical trajectory of modernity. Although the Kelsen/Voegelin exchange ended in failure and bitterness its substance matter goes to...... the heart of modern intellectual history....

  9. Prof. CHEN Han-ping: A Thinker in Principles and Practice of Acupuncture-moxibustion

    Institute of Scientific and Technical Information of China (English)

    杨永清; 王宇; 尹磊淼

    2010-01-01

    The Thinker (Le Penseur) is known as the masterpiece of Auguste Rodin, a distinguished French sculptor, signifying the intellectual activity and creativity of human being. Having put forward a way of "viewing the Earth from the Moon" in developing preclinical and clinical studies of acupuncture, Prof. CHEN Han-ping brought about imaginations to acupuncture scholars with his ideas on the soul, principle, skills and orientations of acupuncture. He deserves the title of "the thinker in principles and practice of acupuncture"[1-3]. The academic ideas of Prof. CHEN Han-ping are now summarized as follows.

  10. Aspectos generales del régimen de los bienes del litoral marítimo. Competencias y limitaciones sobre el Derecho de propiedad

    Directory of Open Access Journals (Sweden)

    Sebastián Barreto Cifuentes

    2013-06-01

    Full Text Available El concepto de “propiedad”, tradicionalmente estudiado con la lógica del Derecho privado, ha sufrido cambios internos (la función social como núcleo esencial y externos (las limitaciones administrativas que hacen necesario estudiarlo con herramientas lógicas y metodológicas del Derecho público. Se debe considerar que un derecho absoluto e ilimitado no requiere mayor atención por parte de la disciplina del Derecho público. La armonización y articulación de los derechos del propietario con las competencias asignadas a las autoridades administrativas, exige una particular atención para proteger los derechos ciudadanos. En desarrollo de lo mencionado, se ha realizado un corto estudio sobre los bienes del litoral marítimo, en particular de las competencias asignadas a las autoridades administrativas sobre estas áreas, así como el límite de estas competencias. También se presentará el análisis de algunos casos reales y potenciales en los cuales se hace necesaria la aplicación de garantías procesales y sustanciales para el respeto de los derechos de los propietarios.

  11. Aspectos generales del régimen de los bienes del litoral marítimo. Competencias y limitaciones sobre el Derecho de propiedad

    Directory of Open Access Journals (Sweden)

    Sebastián Barreto Cifuentes

    2013-07-01

    Full Text Available El concepto de “propiedad”, tradicionalmente estudiado con la lógica del Derecho privado, ha sufrido cambios internos (la función social como núcleo esencial y externos (las limitaciones administrativas que hacen necesario estudiarlo con herramientas lógicas y metodológicas del Derecho público. Se debe considerar que un derecho absoluto e ilimitado no requiere mayor atención por parte de la disciplina del Derecho público. La armonización y articulación de los derechos del propietario con las competencias asignadas a las autoridades administrativas, exige una particular atención para proteger los derechos ciudadanos. En desarrollo de lo mencionado, se ha realizado un corto estudio sobre los bienes del litoral marítimo, en particular de las competencias asignadas a las autoridades administrativas sobre estas áreas, así como el límite de estas competencias. También se presentará el análisis de algunos casos reales y potenciales en los cuales se hace necesaria la aplicación de garantías procesales y sustanciales para el respeto de los derechos de los propietarios.

  12. Producción y consumo de bienes culturales: El caso de las artesanías urbanas de la Ciudad de Buenos Aires

    Directory of Open Access Journals (Sweden)

    Mónica B. Rotman

    2002-12-01

    Full Text Available Este artículo tiene por objeto reseñar algunos de los principales aspectos de un fenómeno cultural citadino: las artesanías urbanas feriales de la Ciudad de Buenos Aires. La problemática abordada contempla las instancias de la producción artesanal, la circulación de estos bienes con énfasis en las Ferias como sitios privilegiados del intercambio y ámbitos relevantes de sociabilidad y el consumo de artesanías. Consideramos que este tipo de producción, que constituye un fenómeno complejo, conforma una práctica cultural heterodoxa, recreando con códigos propios la sociabilidad híbrida que inducen las ciudades contemporáneas.The objective of this article is to outline some of the main aspects of an urban cultural phenomenon: the urban handicrafts from fairs in Buenos Aires city. The issues this paper addresses are handicraft production, the circulation of these goods with emphasis on fairs as privileged places of exchange, sociability and handicraft consumption. I consider this type of production a complex phenomena that shapes an heterodox cultural practice, recreating through its own codes the hybrid sociability that contemporary cities induce.

  13. Association of rs2072183 SNP and serum lipid levels in the Mulao and Han populations

    Directory of Open Access Journals (Sweden)

    Miao Lin

    2012-05-01

    Full Text Available Abstract Background Niemann-pick C1-like 1 (NPC1L1 is a key protein for intestinal cholesterol transportation. Common single nucleotide polymorphisms (SNPs in the NPC1L1 gene have been associated with cholesterol absorption and serum lipid levels. The present study was undertaken to explore the possible association of NPC1L1 rs2072183 1735 C > G SNP and several environmental factors with serum lipid levels in the Mulao and Han populations. Methods Genotyping of the rs2072183 SNP was performed in 688 subjects of Mulao and 738 participants of Han Chinese. The interactions between NPC1L1 1735 C > G polymorphism and several environmental factors on serum lipid phenotypes were tested using the factorial design covariance analysis after controlling for potential confounders. Results The frequency of G allele was lower in Mulao than in Han (29.72% vs. 37.26%, P P P P P P P P P  Conclusions The present study suggests that the rs2072183 SNP in NPC1L1 gene and its association with serum lipid profiles are different between the Mulao and Han populations. The difference in serum lipid profiles between the two ethnic groups might partly result from different rs2072183 SNP or NPC1L1 gene-environmental interactions.

  14. Validating GWAS-Identified Risk Loci for Alzheimer's Disease in Han Chinese Populations.

    Science.gov (United States)

    Wang, Hui-Zhen; Bi, Rui; Hu, Qiu-Xiang; Xiang, Qun; Zhang, Chen; Zhang, Deng-Feng; Zhang, Wen; Ma, Xiaohong; Guo, Wanjun; Deng, Wei; Zhao, Liansheng; Ni, Peiyan; Li, Mingli; Fang, Yiru; Li, Tao; Yao, Yong-Gang

    2016-01-01

    In recent years, genome-wide association studies (GWASs) have identified many novel susceptible genes/loci for Alzheimer's disease (AD). However, most of these studies were conducted in European and populations of European origin, and limited studies have been performed in Han Chinese. In this study, we genotyped 14 single-nucleotide polymorphisms (SNPs) in eight GWAS-reported AD risk genes in 1509 individuals comprising two independent Han Chinese case-control cohorts. Four SNPs (rs11234495, rs592297, rs676733, and rs3851179) in the PICALM gene were significantly associated with late-onset (LO)-AD in populations from Southwest China, whereas SNPs rs744373 (BIN1), rs9331942 (CLU), and rs670139 (MS4A4E) were linked to LO-AD in populations from East China. In the combined Han Chinese population, positive associations were observed between PICALM, CLU, MS4A4E genes, and LO-AD. The association between rs3851179 (PICALM), rs744373 (BIN1), and AD was further confirmed by meta-analysis of Asian populations. Our study verified the association between PICALM, BIN1, CLU, and MS4A4E variants and AD susceptibility in Han Chinese populations. We also discerned some regional differences concerning AD susceptibility SNPs. PMID:25452228

  15. Kes on Hans Sidbäck? / Sari Vasenkari ja Saija Huttunen

    Index Scriptorium Estoniae

    Vasenkari, Sari

    2012-01-01

    Rootsis elavast soomlasest Hans Sidbäckist, kes on lisaks rakendisõidu ja -hobuste koolitamisele spetsialiseerunud ka täkkude, varssade ja noorte ning probleemsete hobuste koolitamisele. Ta on töötanud ka Ypäjä hobumajanduskoolis sõidumeistrina

  16. Brief Report: No Increase in Criminal Convictions in Hans Asperger's Original Cohort

    Science.gov (United States)

    Hippler, Kathrin; Viding, Essi; Klicpera, Christian; Happe, Francesca

    2010-01-01

    Hans Asperger originally used the term "autistic psychopathy" to describe his patients on the autism spectrum, leading to a possible confusion with psychopathic disorder and delinquent behaviour. We conducted a penal register search for 177 former patients of Asperger's clinic with a childhood diagnosis of "autistic psychopathy" or features of the…

  17. De HAN-zorggame: spelenderwijs werken aan ketendenken in de zorg

    NARCIS (Netherlands)

    Bogers, Enide; Westerman, Richard; Faber-de Lange, Brigitte; Weijers, Stef

    2013-01-01

    Hoe kunnen we inhoudelijke kennis, ketenbewustzijn en soft skills op een laagdrempelige, hoog-kwalitatieve wijze aan de zorgprofessionals aanbieden? Dat was de vraag die de HAN gesteld is door zorgprofessionals naar aanleiding van onvoldoende afstemming in de zorgketen. De literatuur liet zien dat e

  18. Building Empire through Argumentation: Debating Salt and Iron in Western Han China

    Science.gov (United States)

    You, Xiaoye

    2010-01-01

    The history of American imperialism, as well as China's strong presence on the contemporary global scene, should encourage American scholars of rhetoric to look beyond the nation-state and study other rhetorical traditions such as Chinese practices of argument. A debate during the Western Han dynasty over the country's economic policies…

  19. Han Suyin’s Autobiographical Novel A Many Splendoured Thing First Published In China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    <正>AMany-Splendoured Thing,an autobiographical novel written by prominent Chinese-British woman writer Han Suyin,is her greatest success and representative work which has established her status in the international literary world. But surprisingly,this famous novel

  20. The Relevance of Hans-Georg Gadamer's Concept of Tradition to the Philosophy of Education

    Science.gov (United States)

    Leiviskä, Anniina

    2015-01-01

    In this article, Anniina Leiviskä argues that the educational relevance of Hans-Georg Gadamer's concept of tradition has remained unacknowledged because of the conservatism that has been associated with Gadamer's hermeneutics, particularly his notion of tradition. Therefore, Leiviskä seeks to reveal the reflective, nonconservative nature of…

  1. Hans J. Massaquoi’s Destined to Witness as an Autobiographical Act of Identity Formation

    Directory of Open Access Journals (Sweden)

    Lindhout, Alexandra E.

    2006-01-01

    Full Text Available In his autobiography, Hans J. Massaquoi describes the discrimination he encountered in Nazi Germany and Liberia because of his mixed racial background. Throughout his life Massaquoi had to cope with identity crises. Through the self-therapeutic discourse in the form of his autobiography, however, Massaquoi developed his hybrid transatlantic African American and African German identity.

  2. Comparison of the Perception of English Learning Between Ethnic Group Students and Han Students

    Institute of Scientific and Technical Information of China (English)

    沈映梅

    2013-01-01

    This paper has analyzed the discrepancies of the perception of English learning between ethnic students and Han studens in a trilingual language context. The research results will be expected to broaden our understanding of the ethnic group students in the minority regions, and to provide some empirical references and implications for teachers.

  3. 'Presence' of the past in the presence (Hans Ulrich Gumbrecht, Eelco Runia)

    NARCIS (Netherlands)

    ter Schure, L

    2006-01-01

    In recent writings historian Eelco Runia (Groningen) and literary theorist Hans Ulrich Gumbrecht (Stanford) have introduced the notion of presence, a new and promising way of thinking about history. Although there are differences between the two authors, both think of presence as the antithesis of '

  4. Antisocial Behavior in Children and Hans Eysenck's Biosocial Theory of Personality: A Review.

    Science.gov (United States)

    Kemp, Dawn E.; Center, David B.

    This paper examines antisocial behavior in children and youth in relation to the biosocial personality theory of Hans Eysenck. It explains Eysenck's theory, which includes a significant role for biological factors in the development of antisocial behavior. The theory holds that three temperament traits--Psychoticism (P), Extroversion (E), and…

  5. [Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu] / Ago Künnap

    Index Scriptorium Estoniae

    Künnap, Ago, 1941-

    2010-01-01

    Arvustus: Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu = Chinese language and languages of northern Europe. Beijing : Zhongguo she hui ke xue chu ban she, 2008

  6. Los bienes de interés cultural de Gáldar (Canarias y el conjunto histórico “Plaza de Santiago” (1981-2006

    Directory of Open Access Journals (Sweden)

    Juan Sebastián López García

    2013-10-01

    Full Text Available En 1981, hace veinticinco años, la zona central de Gáldar fue declarada “Conjunto Histórico Artístico” con la denominación de Plaza de Santiago. Sin embargo no era el primer bien cultural que obtenía una distinción de este tipo, ya que Gáldar había sido pionera en 1949 con el yacimiento de El Agujero y La Guancha, primero de los de carácter arqueológico declarado en Canarias, al que seguiría en 1972 la Cueva Pintada. Hasta la década de los setenta prevalecieron los bienes arqueológicos, situación que se modificó en las dos últimas décadas del siglo XX después del reconocimiento de la Plaza de Santiago y su entorno. Junto con edificaciones religiosas también se incluyeron ejemplos de arquitectura doméstica, completándose con algunos yacimientos prehispánicos. Una particular circunstancia fue la declaración en 1993 del pago de Barranco Hondo de Abajo, lo que convertía a Gáldar en el primer municipio de Canarias que contaba con dos conjuntos históricos, siendo éste a la vez el primero de la comunidad autonóma con características rurales. De la relación de los declarados, si exceptuamos la mayoría de los de carácter arqueológico, buena parte son urbanos. Una característica es que se incluyen categorías variadas, incluyendo la existencia de una zona arqueológica junto a un conjunto histórico y varios monumentos (de arquitectura religiosa y doméstica. Este hecho es lógico si se tiene en cuenta la particularidad de Gáldar y su condición de núcleo histórico de superposición.Twenty five years ago, in 1981, the central zone of Galdar was declared an "Historic Artistic Site" with the name of Plaza de Santiago. But this was not the first cultural asset to obtain a distinction of this kind, as Galdar pioneered protection of this kind with the El Agujero and La Guancha site, the first archaeological site declared in the Canary Islands, followed by La Cueva Pintada, in 1972. Archaeological assets prevailed up

  7. La evolución de las exportaciones de bienes de China: una visión panarómica = Chinese goods exports development: An overview

    Directory of Open Access Journals (Sweden)

    Ana Salvador Chamorro

    2014-07-01

    Full Text Available Resumen El proceso de reforma económica que ha experimentado la economía de China es uno de los fenómenos de mayor relevancia en la evolución de la Economía Mundial en los últimos treinta años y, sin duda, seguirá siéndolo en el futuro. Dentro de este proceso, la apertura al exterior, que el gobierno chino inició en 1978, ha situado al país en un lugar de máxima relevancia dentro de los flujos comerciales y financieros internacionales. En este contexto, el objetivo de este trabajo es intentar realizar un análisis general de la evolución del comercio exterior de China en las últimas décadas, prestando especial atención a sus exportaciones de bienes y poniendo énfasis en los cambios experimentados durante los últimos años. Abstract The process of economic reform that has experienced the Chinese economy is one of the most important events in the evolution of the World Economy in the past 30 years, and will undoubtedly remain so in the future. Within this economic reform, the opening process that the Chinese Government began in 1978, has put the country in a place of utmost importance in the international trade and financial flows. In this context, this paper try to perform an analysis of the evolution of China's foreign trade in recent decades, with particular attention to its exports and emphasizing the changes in recent years.

  8. Para além da autoconsciência moderna: a historiografia de Hans Ulrich Gumbrecht Beyond modern self-consciousness: the historiography of Hans Ulrich Gumbrecht

    Directory of Open Access Journals (Sweden)

    Valdei Lopes de Araujo

    2006-12-01

    Full Text Available Neste artigo, apresento uma análise dos aspectos historiográficos da obra de Hans Ulrich Gumbrecht. Acompanhado o desenvolvimento de sua teoria da modernidade e das conseqüências dessa teoria para a escrita da história e para a auto-consciência disciplinar. Por fim, proponho uma releitura da história da historiografia através dos dois tipos de culturas propostas por Gumbrecht, ou seja, culturas de sentido e culturas de presença. Argumento que mesmo que a historiografia moderna possa ser caracterizada como predominantemente ancorada na produção de sentido, aspectos centrais de sua história só podem ser explicados através de elementos típicos da produção de presença.This paper analyses some historiographical aspects of Hans Ulrich Gumbrecht's work, particularly his theory of modernity and its consequences to the writing of history and its disciplinary self-conscious. Finally, it is proposed a reinterpretation of the history of historiography based on the distinction between cultures of presence and cultures of meaning. It is argued that despite the fact that the elements of meaning are predominant in the constitution of modern historiography, the forces acting in its constitution cannot be explained without typical elements of a culture of presence.

  9. Little Hans and attachment theory: Bowlby's hypothesis reconsidered in light of new evidence from the Freud Archives.

    Science.gov (United States)

    Wakefield, Jerome C

    2007-01-01

    Bowlby (1973), applying attachment theory to Freud's case of Little Hans, hypothesized that Hans's anxiety was a manifestation of anxious attachment. However Bowlby's evidence was modest; Hans was threatened by his mother with abandonment, expressed fear of abandonment prior to symptom onset, and was separated from his mother for a short time a year before. Bowlby's hypothesis is reassessed in light of a systematic review of the case record as well as new evidence from recently derestricted interviews with Hans's father and Hans in the Freud Archives. Bowlby's hypothesis is supported by multiple additional lines of evidence regarding both triggers of separation anxiety preceding the phobia (e.g., a funeral, sibling rivalry, moving, getting his own bedroom) and background factors influencing his working model of attachment (mother's psychopathology, intense marital conflict, multiple suicides in mother's family) that would make him more vulnerable to such anxiety. Bowlby's hypothesis is also placed within the context of subsequent developments in attachment theory. PMID:18524087

  10. [The activity of searching for books of Shang Han Lun (Treatise on Cold Pathogenic Diseases) of the Song edition].

    Science.gov (United States)

    Qian, Chao-chen

    2010-01-01

    Originally, Shang Han Lun in the Song edition referred to the Shang Han Lun with large and small Chinese characters printed in the Northern Song Dynasty. In the Ming Dynasty, its only edition of Shang Han Lun with small Chinese characters was again block-printed in Zhong Jing Quan Shu (Zhongjing's Complete Works) by Zhao Keimei and then the original one disappeared. So the Shang Han Lun in Zhong Jing Quan Shu was considered as the Song edition. Only 6 sets were in existence in the world, and were read by myself; I have detailed records and photos of 5 of them. The article is the result of textual research on Shang Han Lun of Zhong Jing Quan Shu preserved in Taiwan National Palace Museum. PMID:20403262

  11. Study on measuring social cost of water pollution: concentrated on Han River water system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kwang Im; Min, Dong Gee; Chung, Hoe Seong; Lim, Hyun Jeong; Kim, Mee Sook [Korea Environment Institute, Seoul (Korea)

    1999-12-01

    Following the economic development and the progress of urbanization, the damage on water pollution has been more serious but a social cost caused by water pollution cannot be measured. Although the need of water quality preservation is emphasized, a base material for public investment on enhancing water quality preservation is not equipped yet due to the absence of economic values of water resource. Therefore it measured a cost generated by leaving pollution not treated water quality in this study. To measure the usable value of water resource or the cost of water pollution all over the country should include a national water system, but this study is limited on the mainstream of Han River water system from North Han River through Paldang to Chamsil sluice gates. Further study on Nakdong River and Keum River water systems should be done. 74 refs., 4 figs., 51 tabs.

  12. Genetic variants identified by GWAS was associated with colorectal cancer in the Han Chinese population

    Directory of Open Access Journals (Sweden)

    Hui-Ping Qiao

    2015-01-01

    Full Text Available Aim of Study: Colorectal cancer (CRC, now the third most common cancer across the world, is known to aggregate in families. Recently, genome-wide association studies have identified two single nucleotide polymorphisms (SNP associated with CRC in Caucasians. Materials and Methods: To validate whether the same variations conferred risk to CRC in the Han Chinese population, we genotyped 760 individuals (380 controls and 380 cases samples recruited from the Han Chinese origin. Results: We found rs11987193 in 8p12 (P = 0.0472 after correction, OR = 0.751 was significantly associated with CRC but rs12080929 in 1p33 (P = 0.0650 after correction, OR = 0.750 was not. Conclusion: Our findings supported that rs11987193 is a susceptibility locus for CRC, and gene DUSP4 was possible to play a role in the pathology of CRC.

  13. Hans-Peter Schultze, a great paleoichthyologist for whom work is synonymous with enjoyment

    Directory of Open Access Journals (Sweden)

    R. Cloutier

    2002-01-01

    Full Text Available In the summer of 1982, Hans-Peter Schultze and Gloria Arratia were invited to a small museum located on a fossiliferous site of the Devonian Escuminac Formation in Miguasha, Quebec, eastern Canada, Hans-Peter was to work with Marius Arsenault, the director of the Miguasha Museum, on the skull of the elpistostegalid Elpistostege watsoni, a species closely related to basal tetrapod. In addition, he went through the collections to describe and measure numerous juvenile specimens of the osteolepiform. Eusthenopteran foordi. As expected, there two projects turned out to be important contributions in lower vertebrate paleontology and systematics: one on the origin of tetrapods (1985, and the second one on growth patterns of a Late Devonian fish (1984. During his visit to Miguasha, Hans-Peter also spent time digging for fossils and drawing numerous specimens in the collection. In addition, in order to help the personnel of the museum to identify some of the Escuminac fished, he created an identification key based on the gross morphology of the scales. For a small group of undergraduate students, hired at the museum during the summer as naturalists, it was a unique opportunity to discuss paleontology with a leading researcher. We were amazed by his willingness to talk to us, even if then most of us only spoke French! For the first time, we were exposed to Hennigian methodology and its usage in vertebrate paleontology during and evening lecture that Hans-Peter prepared for us. His lecture was delightful; it was an intensive course in lower vertebrate anatomy, and an intellectual journey among the philosophers Karl Marx and Karl Popper, the entomologists Willy Hennig and Lars Brundin, and "The Band of Four" (Rosen et al., 1981. It was for most of us our first exposure to science, as it should be done. We were all impressed by his knowledge and above all by his simplicity and friendliness. Two years later I started my Ph.D. at The University of Kansas

  14. Analysis of the private, collective, and relational self-cognitions among Han and Tibetan Chinese.

    Science.gov (United States)

    Huang, Wei; Mamat, Marhaba; Shang, Rui; Zhang, Tianyang; Li, Hao; Wang, Yao; Luo, Wei; Wu, Yanhong

    2014-08-01

    Differences in the concepts of private, collective, and relational selves between two Chinese ethnic groups, the Han and Tibetan-adhering to the philosophies of Confucianism and Tibetan Buddhism, respectively-were examined. 128 students (54 men, 74 women; M age = 20.9 yr., SD = 2.2) completed the revised Twenty Statements Test and self-reference paradigm. Study 1 found that for Han participants relational and private selves were ranked similarly and as more important than the collective self. Studies 2 and 3 found that adjective words describing private and relational selves were recalled in greater proportions than words describing the collective self. Tibetan participants showed no significant differences between the three self-cognitions. The findings correspond to differences in self-identity among these two subcultures. PMID:25153957

  15. Genetic polymorphism of 17 Y-STR loci in Han Chinese living in Lanzhou.

    Science.gov (United States)

    Sun, Hong-bing; Yang, Xin; Ha, Fei; Zhang, Zi-long

    2013-12-01

    The genetic polymorphism across 17 Y-STR loci in a population of Han Chinese in Lanzhou was investigated. Haplotypes and allele frequencies for the 17 Y-chromosomal STRs loci DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438 and DYS448 were determined in 500 healthy unrelated autochthonous males from Lanzhou. The results showed that no shared haplotypes were observed. Gene diversity values ranged from 0.3987 (DYS391) to 0.9740 (DYS385a,b). It was concluded that these loci will be very useful for human identification in forensic cases and paternity tests within the Han Chinese population inhabiting Lanzhou. PMID:24337856

  16. Single nucleotide polymorphisms of TNFAIP3 are associated with systemic lupus erythematosus in Han Chinese population.

    Science.gov (United States)

    Han, J-W; Wang, Y; Li, H-B; Alateng, C; Bai, Y-H; Sun, Z-Q; Lv, X-X; Wu, R-N

    2016-04-01

    The polymorphisms of tumour necrosis factor alpha-induced protein 3 (TNFAIP3) have been found to associate with several autoimmune diseases. This study aimed to explore the association of single nucleotide polymorphisms (SNPs) of TNFAIP3 gene with systemic lupus erythematosus (SLE) in Han Chinese. Thirty-two SNPs were genotyped in 284 patients with SLE and 630 controls using the ligation detection reaction (LDR) method. The quality control steps and statistical analyses were performed using the plink 1.07 package and haploview software. We found that 13 SNPs in TNFAIP3 showed significant association with SLE (P  0.27). All 13 SNPs showed most significant association in the dominant model. In haplotype analysis, a long risk SNP haplotype (GCCCGTGTCATGG) showed most significant association (P = 1.00 × 10(-4) ). In conclusion, our data suggest that TNFAIP3 is a susceptible gene for SLE in the Han Chinese population. PMID:26846592

  17. Y-chromosome haplotype distribution in Han Chinese populations and modern human origin in East Asians

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    We investigated the distribution of Y-chromosome haplotype using 19 Y-SNPs in Han Chinese populations from 22 provinces of China. Our data indicate distinctive patterns of Y chromosome between southern and northern Han Chinese populations. The southern populations are much more polymorphic than northern populations. The latter has only a subset of the southern haplotypes. This result confirms the genetic difference observed between southern and northern ethnic populations in East Asia. It supports the hypothesis that the first settlement of modern hu-mans of African origin occurred in the southern part of East Asia during the last Ice Age, and a northward migration led to the peopling of northern China.

  18. Association of Gghrelin Polymorphisms with Metabolic Syndrome in Han Nationality Chinese

    Institute of Scientific and Technical Information of China (English)

    LING-LING XU; HONG-DING XIANG; CHANG-CHUN QIU; QUN XU

    2008-01-01

    Objective To investigate the association of ghrelin gene polymorphisms with metabolic syndrome in Han Nationality Chinese. Methods A total of 240 patients with metabolic syndrome annd 427 adults aged above forty years were recruited. Genotypes were determined by polymerase chain reaction and restriction fragment lengthpolymorphism analysis.Results The allelic frequency of the Leu72Met polymorphismwas 17.3% in the patient group and 11.9% in the control group(x2=7.36, P=0.007). Metabolic syndrome was more prevalent among carriers of the Met72 variant (43.8 vs 33.1%, age- and sex-adjusted odds ratio=1.57, P=0.01). No Arg51Gln variants were found in our study subjects. Conclusion Rather than being associated with its individual components, Leu72Met polymorphism is associated with metabolic syndrome in the Han Nationality Chinese. Arg51Gln polymorphism is rare in the Hart Nationality Chinese.

  19. Safety assessment of Novi Han radioactive waste repository - features, problems, results and perspectives

    International Nuclear Information System (INIS)

    This paper summarizes the work done and the achievements reached in the Novi Han radioactive waste repository safety assessment within the IAEA Model Project 'Increasing the safety of Novi Han radioactive waste repository BUL 4/005'. The overall safety assessment has a wide context, but the work reported here relates only to some details and results concerning the development and implementation of the appropriate methodology approach, model and computer code used for the calculations. Different steps and procedures are included for a better practical understanding of the obtained results during the safety assessment performance. The methodology approach is widely based on an international experience in safety analysis and implemented for evaluation computer code AMBER, which is one of the recommended from the safety assessments experts. (author)

  20. Association of AKT1 gene polymorphisms with sporadic Parkinson's disease in Chinese Han population.

    Science.gov (United States)

    Li, Xiao-Yuan; Teng, Ji-Jun; Liu, Yang; Wu, Yu-Bin; Zheng, Yu; Xie, An-Mu

    2016-08-26

    Genetic variants of AKT1 have been shown to influence brain function of Parkinson's disease (PD) patients, and in this paper our aim is to investigate the association between the three single-nucleotide polymorphisms (rs2498799; rs2494732; rs1130214) and PD in Han Chinese. 413 Han Chinese PD patients and 450 healthy age and gender-matched controls were genotyped using the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) method. Both the patient and control groups show similar genotype frequencies at the three loci: rs2498799, rs2494732 and rs1130214. We are able to identify a significant difference in the frequencies of genotype (p=0.019) and G allele (OR=0.764, 95% CI=0.587-0.995, p=0.045) both at rs2498799 between the patient and control groups. Furthermore, the association of subjects with GG genotypes versus those with GA+AA genotype remain significant after adjusting for age in the Han Chinese female cohort (OR=0.538, 95%CI=0.345-0.841, p=0.006), which is especially evident in the late-onset cohort (OR=0.521, 95%CI=0.309-0.877, p=0.012). In contrast, allele frequencies at rs2494732 and rs1130214 were similar between patients and controls in all subgroup analyses. These results suggest that polymorphism of AKT1 locus is associated with risk of PD and that the G allele at rs2498799 may decrease the risk of PD in the North-eastern part of Han Chinese female population. PMID:27353512

  1. 50 aastat Euroopa integratsiooni: aeg uueks alguseks / Hans-Gert Pöttering

    Index Scriptorium Estoniae

    Pöttering, Hans-Gert, 1945-

    2007-01-01

    Ilmunud ka: Virumaa Teataja, 23. märts 2007, lk. 1; Pärnu Postimees, 24. märts 2007, lk. 19; Koit, 24. märts 2007, lk. 6; Põhjarannik, 24. märts 2007, lk. 2; Severnoje Poberezhje, 24. märts 2007, lk. 2. Euroopa Parlamendi presidendi Hans-Gert Pötteringi mõtted Euroopa Ühenduse asutamislepingu sõlmimise 50. aastapäeva puhul

  2. The Practice of Arbitration. Essays in Honor of Hans van Houtte

    OpenAIRE

    2012-01-01

    This book offers a series of commentaries on noteworthy arbitral awards and court decisions on arbitration. All contributions focus on the practice of arbitration. Influential authors with proven arbitration experience share their insights on celebrated and less well-known cases, drawn from various countries, various arbitration institutions and including both commercial and investment arbitration. This collection of essays celebrates the work and scholarship of Hans Van Houtte, who has ...

  3. Natural law Judaism? The genesis of bioethics in Hans Jonas, Leo Strauss, and Leon Kass.

    Science.gov (United States)

    Vogel, Lawrence

    2006-01-01

    Leon Kass is much misunderstood. He is not simply a Republican ideologue who tailored his ideas to break out of the ivory tower and into the halls of power. Nor does he look simply to use human nature as a moral guide. When the full range of his writings is considered and set in the tradition of his teachers, Hans Jonas and Leo Strauss, what emerges is a natural law position colored by religious revelation. PMID:16776021

  4. Association between ERAP1 gene polymorphisms and ankylosing spondylitis susceptibility in Han population

    OpenAIRE

    Wang, Jian; Li, Hang; Wang, Jianwei; Gao, Xiang

    2015-01-01

    Purposes: The present study was designed to investigate the relationship between endoplasmic reticulum amino peptidase 1 (ERAP1) gene polymorphisms and ankylosing spondylitis (AS) in Han population of Shaanxi province. Methods: 100 AS patients and 100 healthy people were enrolled in present study as case and control groups respectively, and the control group was matched with the case group by age and gender. ERAP1 gene rs27434 and rs7711564 polymorphisms were test by TaqMan probe genotyping m...

  5. Gardens and Gateways: Journeys within the Vision of Han-shan

    OpenAIRE

    Beidler, Anne

    2011-01-01

    Although rooted in the work of the T’ang poet Han-shan, this paper is ultimately about the ways in which writers and artists engage with what they experience in the world. The work of filmmaker Trin T Minh-Ha, poems by W.S. Merwin, Burtin Watson’s translations, and the thoughts on the creative process of translation by Tony Barnstone and Gary Snyder have all informed my work as an artist and the images I present here.

  6. Sintoma e invenção no caso Pequeno Hans de Freud.

    Directory of Open Access Journals (Sweden)

    Paulo Eduardo Viana Vidal

    2015-07-01

    Full Text Available As we will try to show in the article, initial result of a research on the symptom in Freud and Lacan, Freud's case study of Little Hans, published over one hundred years ago, teaches us how a subject whose world collapsed and who is taken by anguish, can invent, rig up with the remaining fragments a symptom that reorganizes for himself a liveable world.

  7. The first Koç Han: Pioneering modern architecture in Ankara

    Directory of Open Access Journals (Sweden)

    Oya Atalay Franck

    2013-01-01

    Full Text Available Koç Holding is the most established conglomerate in Turkey. Th e company’s beginnings date from the mid 1920s, when Ahmet Vehbi Koç, founder of Koç Holding, had his first own company registered with the Ankara Chamber of Commerce. In 1932, Koç moved his business from his father’s store on Anafartalar Street to a new building, the first Koç Han, erected the same year on Çankırı Street Nr.13 in Ulus. Th e building’s designer was Swiss-Austrian architect Ernst Arnold Egli, who had come to Turkey only five years earlier upon invitation by the government to work as chief architect of the Ministry of National Education. During his stay, which lasted from 1927 until 1940, Egli realized about 40 projects and worked on many more. Koç Han is the rare example of a commercial building by Egli. At a time when the urban aspect of the old town center of Ankara consisted mostly of one-or two-storeyed stone-and-wood houses, the first Koç Han represented an altogether new building type for the town, in being a multipurpose edifice with space for shops at street level, with large storage facilities below ground, and providing off ices and housing on the upper fl oors. Th e functional rigor of the plan and the sober modernism of the building’s facades contrasted strongly with the architecture of the time. In this respect, the first Koç Han was a strong statement regarding Ahmet Vehbi Koç’s belief in a modern Turkey and to the contribution of the building’s architect, Ernst Arnold Egli, to this project.

  8. CPPCC Vice Chairman and CPAPD President Mr.Han Qide Visits Mexico and Argentina via France

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    <正>At the invitation of the Mexican Council on Foreign Relations(COMEXI)and the World Peace Council(WPC),Mr.Han Qide,Vice Chairman of the Chinese People’s Political Consultative Conference(CPPCC)and President of the Chinese People’s Association for Peace and Disarmament(CPAPD)attended the WPC international conference,visited Mexico and Argentina,and transited through

  9. Die Psychobiologie des Hans Lungwitz (1881 - 1967) im Spiegel der Rezensionen

    OpenAIRE

    Fischbach, Christine

    2006-01-01

    Der Arzt und Philosoph Hans Lungwitz (1881-1967) schuf nach Jahren der Tätigkeit als Sozialreformer und praktischer Arzt und nach intensiver Auseinandersetzung mit der Psychoanalyse eine eigene Weltanschauungslehre, die Psychobiologie, deren Kernstück die Lösung des Leib-Seele-Problems bildet. Die Entstehung des Bewusstseins ist Lungwitz zufolge an die Hirnfunktionen gekoppelt und damit rein biologischer Natur – die Seele ist nicht existent. Auf insgesamt mehr als 5000 Seiten - in einem achtb...

  10. La Torre de Hanói y los Qn Grafos

    Directory of Open Access Journals (Sweden)

    Mª Milagros Latasa Asso

    2011-10-01

    Full Text Available La Torre de Hanói es uno de los hallazgos matemáticos más ingeniosos de la matemática recreativa. Gracias a una leyenda con tinte oriental hoy se conoce de modo universal. Se describen en este artículo las relaciones entre las soluciones del rompecabezas y los ciclos hamiltonianos en los grafos Qn.

  11. Environmental monitoring and radiation protection programs of Novi Han radioactive waste repository

    International Nuclear Information System (INIS)

    The system for monitoring and control as an important part of the safety management of the Novi Han Radioactive Waste Repository contains two independent programs: environmental monitoring of the site (controlled area), the restricted access area and the surveillance area (supervised area) of the repository and radiation protection program including personal dosimetric control and indoor dosimetric control of workplaces in the buildings of the repository. The main activities related to the programs implementation are presented

  12. Enhanced Diabetes Susceptibility in Community Dwelling Han Elders Carrying the Apolipoprotein E 3/3 Genotype

    OpenAIRE

    Ban, Chun-Xia; Zhong, Li; Wang, Tao; Zhu, Min-jie; Wang, Jing-Hua; Zhang, Zhen-lian; Wang, Zhe; Su, Ning; Liu, Yuan-Yuan; Shi, Yan-chen; Xiao, Shi-fu; Xia LI

    2016-01-01

    Despite Apolipoprotein E (ApoE) being one of the main apolipoproteins in the blood, the association between its genotype and the high cholesterol or blood glucose levels commonly seen in clinical practice is inconclusive. Such research is also lacking in the Han population. The aim of this study was to investigate the association between APOE genotype, diabetes, and plasma glucose and lipid levels. We included 243 community-dwelling elderly residents in this study. Participant APOE genotypes ...

  13. Association of Lumican Gene with Susceptibility to Pathological Myopia in the Northern Han Ethnic Chinese

    OpenAIRE

    Yang Li; Yudong Wu; Zhongjun Zhou; Tingzhun Zhu; Fengju Zhang

    2009-01-01

    Pathological myopia is a severe hereditary ocular disease leading to blindness. It is urgent and very important to find the pathogenesis and therapy for this disease. The purpose of the study is to analyze sequences of lumican and decorin genes with pathological myopia(PM) and control subjects to verify the relationship between lumican, decorin genes and PM in Northern Han Chinese. We collected and analyzed the blood samples of 94 adults (including 12 pedigree cases and 82 sporadic cases) wit...

  14. Cost Optimization of a 3-index Maritime Container Transportation Problem using the Modified Han Algorithm

    OpenAIRE

    Carp Doina; Popa Constantin; Serban Cristina

    2014-01-01

    The Modified Han (MH) algorithm aims at providing a cost optimized solution to real world maritime container transportation problems, which often are unbalanced and inconsistent. By modelling a 3-index container transportation problem as an inconsistent systems of linear inequalities, we apply the MH algorithm and get the transportation cost that is then compared with the one provided by the classical Simplex algorithm. The results show that the MH algorithm may have an effect on cost reducti...

  15. Action music - das Konzept der musik-theatralischen Kompositionen von Hans Werner Henze 1966 – 1976

    OpenAIRE

    Han, Sang Myung

    2010-01-01

    The new, strengthened political conviction to prove himself as a useful composer for his society motivated the composer Hans Werner Henze, born in 1926. He had an urgent longing for change, starting, therefore, his intense involvement directly with political undertakings in 1966. The leading musical aesthetic, “musica impura”, offered him the basis for which to conceptualize a new sort of music. Freed from the form of the traditional opera, Henze created a new form of stage art. This rema...

  16. Female Specific Association between NNMT Gene and Schizophrenia in a Han Chinese population

    OpenAIRE

    Wang, Guo-Xia; Zhang, Yong; Lv, Zhuang-wei; Sun, Mao; Wu, Dan; Chen, Xin-Yu; Wu, Yuan-ming

    2014-01-01

    Accumulating evidence has shown that alterations in one carbon metabolism might play an important role in the pathogenesis of schizophrenia (SZ). Nicotinamide-N-methyltransferase (NNMT) is one of the key enzymes of one-carbon metabolism. To examine whether NNMT gene was associated with SZ in Han Chinese population, we selected seven single nucleotide polymorphisms (SNPs) in NNMT gene, and investigated its association with SZ from a cohort of 42 SZ patients and 86 healthy controls by Mass-ARRA...

  17. Autonomous Dynamics in Neural networks: The dHAN Concept and Associative Thought Processes

    OpenAIRE

    Gros, Claudius

    2007-01-01

    The neural activity of the human brain is dominated by self-sustained activities. External sensory stimuli influence this autonomous activity but they do not drive the brain directly. Most standard artificial neural network models are however input driven and do not show spontaneous activities. It constitutes a challenge to develop organizational principles for controlled, self-sustained activity in artificial neural networks. Here we propose and examine the dHAN concept for autonomous associ...

  18. Von Prag nach New York Hans Kohns (1891-1971) intellektuelle Biographie

    OpenAIRE

    Langeheine, Romy

    2013-01-01

    Hans Kohn (1891-1971) continues to be considered as a founding father of the academic research on and interpretation of nationalism. In more than thirty books and hundreds of articles he outlined his theory of this worldwide phenomenon. His theory is well-known as the so called “Kohn Dichotomy”. Based on the main categories of West and East, understood as metaphors and not geographic locations, he differentiated between two forms of nationalism: The Western model, based on the ...

  19. Mitochondrial DNA Haplogroups and the Risk of Sporadic Parkinson's Disease in Han Chinese

    OpenAIRE

    Ya-Fang Chen,; Wan-Jin Chen; Xiao-Zhen Lin; Qi-Jie Zhang; Jiang-Ping Cai; Chia-Wei Liou; Ning Wang

    2015-01-01

    Background: Mitochondrial dysfunction is linked to the pathogenesis of Parkinson′s disease (PD). However, the precise role of mitochondrial DNA (mtDNA) variations is obscure. On the other hand, mtDNA haplogroups have been inconsistently reported to modify the risk of PD among different population. Here, we try to explore the relationship between mtDNA haplogroups and sporadic PD in a Han Chinese population. Methods: Nine single-nucleotide polymorphisms, which define the major Asian mtDNA ...

  20. Hans Bethe and Physics in/of the 20th Century

    Energy Technology Data Exchange (ETDEWEB)

    Schweber, Silvan [Brandeis University

    2012-12-12

    I will present some facets of Hans Bethe’s life to illustrate how I have used biography to narrate certain aspects of the history of twentieth century physics. I will focus on post World War II quantum field theory, on the relation between solid state/condensed matter physics and high energy physics, and make some observations regarding certain “top down” views in solid state physics in postmodernity.

  1. L’apprentissage du bien-être animal chez de futures professionnels animaliers : des éthiques animals malmenées

    Directory of Open Access Journals (Sweden)

    Vidal Michel

    2015-01-01

    Full Text Available Les débats dont le bien-être animal est l’objet entre chercheurs, professionnels et associations en font une question socialement vive scientifico-éthique. Ils en interrogent l’éducabilité alors que cette notion est prise en compte dans les curricula de l’enseignement agricole. Envisageant son enseignement au travers d’une éducation à l’empathie interspécifique, nous questionnons les facteurs susceptibles de l’influencer. Nous nous fondons sur le discours de sept élèves en baccalauréat professionnel relevant de l’élevage d’animaux de production ou d’animaux de compagnie durant deux années de formation. Six élèves, quelle que soit leur filière de formation, souhaitent créer une relation affective sans nécessairement développer une attitude empathique durant la formation. Parmi les facteurs responsables, nous distinguons (1 un manque de confiance en soi de l’élève, (2 des motivations égocentrées primant sur des motivations zoocentrées, (3 la loyauté et les habitudes acquises à l’égard des pratiques parentales, (4 la conformation aux pratiques et idéologies dominantes du monde professionnel, (5 des facteurs associés aux situations d’enseignement (savoirs et pratiques de référence qui font autorité, valeurs de conformité primant sur des valeurs éthiques, dissociation de la dimension relationnelle et productive de l’élevage, jugements négatifs portés par l’enseignant et les élèves originaires du monde agricole. Ces facteurs généreraient des mécanismes de défense chez l’élève nuisibles au développement d’un raisonnement affectivo-éthique critique.

  2. Variants in 9p21 Predicts Severity of Coronary Artery Disease in a Chinese Han Population.

    Science.gov (United States)

    Jing, Jinjin; Su, Li; Zeng, Ying; Tang, Xiaojun; Wei, Jie; Wang, Long; Zhou, Li

    2016-09-01

    Recent genome-wide association studies identified the common genetic variants in 9p21 were associated with the coronary artery disease (CAD). However, whether this locus could predict the severity of CAD in Chinese Han population is unclear. 499 CAD patients who underwent coronary angiography (CAG) have been enrolled for this study. The single-nucleotide polymorphisms rs2383207 and rs2383206 in 9p21 were genotyped in 499 CAG cases and 1519 controls in Chinese Han population. The gene dosage of 9p21 was stratified by the degree of vascular lesions and tested for association with the severity of CAD. Rs2383207 and rs2383206 demonstrated significant associations with 2-vessel and 3-vessel disease (P = 2.0×10(-3) and 1.9×10(-4) , respectively). GG genotypes of rs2383206 occurred higher proportion of left main trunk (LM) disease (P = 6.0×10(-3) ). GG genotypes of rs2383207 occurred higher proportion of left anterior descending artery disease (LAD) and right CAD (RCA) (P = 2.7×10(-6) and 1.6×10(-4) , respectively). The risk allele G of rs2383207 was associated with severity of CAD estimated by the Gensini score (P = 3.6×10(-5) ). Rs2383207 may strongly influence the development of CAD in Chinese Han population. The gene dosage in 9p21 could predict the severity of CAD. PMID:27461153

  3. Hans von Bülow: creativity and neurological disease in a famous pianist and conductor.

    Science.gov (United States)

    Wöhrle, Johannes C; Haas, Frithjof

    2007-01-01

    Hans von Bülow (1830-1894) was a conductor and pianist of worldwide reputation and founder of many stylistic interpretations of classic and romantic symphonies. The close friendship with Richard Wagner, but not the enthusiastic admiration of his dramatic musical opus, ended abruptly when Hans von Bülow became aware of the betrayal of his wife Cosima and Richard Wagner. Hans von Bülow reported symptoms and signs of neurological disease in many letters that were kept and edited by his second wife Marie. For decades he suffered from chronic neuralgiforme headaches, which were caused by a tumor of the cervical radicular nerves. At the age of 45 years, he suddenly developed a motorsensory deficit in the right arm and hand and a contralateral facial deficit, suggestive of brainstem infarction. He recovered and celebrated even greater successes as a musician, although phases of major depression also interfered with his professional life. In the last, phase of his life, he experienced the consequences of generalized atherosclerosis and cerebral microangiopathy. It was a second cerebrovascular accident of the brainstem that caused his death, only 10 months after his last concert performance. Although his death occurred in Egypt, an autopsy was performed by Professor Ludwig Edinger and the results will be presented. PMID:17495513

  4. A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese.

    Science.gov (United States)

    Jiang, Teng; Tan, Lan; Chen, Qi; Tan, Meng-Shan; Zhou, Jun-Shan; Zhu, Xi-Chen; Lu, Huan; Wang, Hui-Fu; Zhang, Ying-Dong; Yu, Jin-Tai

    2016-06-01

    Two recent studies have identified that a rare coding variant (p.R47H) in exon 2 of triggering receptor expressed on myeloid cells 2 (TREM2) gene is associated with Alzheimer's disease (AD) susceptibility in Caucasians. This association was not successfully replicated in Han Chinese, where this variant was rare or even absent. Previously, we resequenced TREM2 exon 2 to investigate whether additional rare variants conferred risk to AD in our cohort. Although several new variants had been identified, none of them was significantly associated with disease susceptibility. Here, to test whether TREM2 is truly a susceptibility gene of AD in Han Chinese, we extend our previous study by sequencing the other four exons of TREM2 in 988 AD patients and 1,354 healthy controls. We provided the first evidence that a rare coding variant (p.H157Y) in TREM2 exon 3 conferred a considerable risk of AD in our cohort (Pcorrected = 0.02, odds ratio = 11.01, 95% confidence interval: 1.38-88.05). This finding indicates that rare coding variants of TREM2 may play an important role in AD in Han Chinese. PMID:27067662

  5. Evaluation of Four Genetic Variants in Han Chinese Subjects with High Myopia

    Directory of Open Access Journals (Sweden)

    Zimeng Ye

    2015-01-01

    Full Text Available High myopia is one of the leading causes of blindness worldwide. However, the exact etiology of high myopia remains unraveled despite numerous attempts of elucidation. Previous genome-wide association study (GWAS has revealed that four single nucleotide polymorphisms (SNPs, including rs2969180, rs1652333, rs9307551, and rs7837791, were associated with high myopia in Caucasians. The present study was conducted to investigate whether these genetic variants were associated with high myopia in Han Chinese. These four SNPs were genotyped by SNaPshot method in a Han Chinese cohort composed of 827 patients with high myopia and 988 healthy controls. Among the SNPs genotyped, only rs9307551 was found to be significantly associated with high myopia in this study. Carriers of rs9307551A allele, AA, and AC genotypes had an increased risk of high myopia (OR = 1.33, 95% CI 1.14–1.54; OR = 1.75, 95% CI 1.28–2.38; OR = 1.59, 95% CI 1.24–2.01, resp.. Interestingly, when split by gender, the association between rs9307551 and high myopia proved to be gender-specific with significance observed only in females but not males. These findings suggested that the SNP of rs9307551 showed a gender-specific association with high myopia in the Han Chinese population. In addition, LOC100506035, a lincRNA gene, might play a crucial role in the susceptibility to high myopia.

  6. Association study of SHANK3 gene polymorphisms with autism in Chinese Han population

    Directory of Open Access Journals (Sweden)

    Ruan Yan

    2009-06-01

    Full Text Available Abstract Background Autism, a heterogeneous disease, is described as a genetic psychiatry disorder. Recently, abnormalities at the synapse are supposed to be important for the etiology of autism.SHANK3 (SH3 and multiple ankyrin repeat domains protein gene encodes a master synaptic scaffolding protein at postsynaptic density (PSD of excitatory synapse. Rare mutations and copy number variation (CNV evidence suggested SHANK3 as a strong candidate gene for the pathogenesis of autism. Methods We performed an association study between SHANK3 gene polymorphisms and autism in Chinese Han population. We analyzed the association between five single nucleotide polymorphisms (SNPs of the SHANK3 gene and autism in 305 Chinese Han trios, using the family based association test (FBAT. Linkage disequilibrium (LD analysis showed the presence of LD between pairwise markers across the locus. We also performed mutation screening for the rare de novo mutations reported previously. Results No significant evidence between any SNPs of SHANK3 and autism was observed. We did not detect any mutations described previously in our cohort. Conclusion We suggest that SHANK3 might not represent a major susceptibility gene for autism in Chinese Han population.

  7. Population data of 17 short tandem repeat loci in 2923 individuals from the Han population of Nantong in East China.

    Science.gov (United States)

    Yang, Min; Li, Liming; Han, Haijun; Jin, Li; Jia, Dongtao; Li, Shilin

    2016-09-01

    Nantong is located in mid-eastern China, and the Han population in Nantong may be greatly affected by population admixture between northern and southern Han Chinese populations. In this study, we analyzed 17 autosomal short tandem repeat (STR) loci on 2923 unrelated individuals collected from the Han population of Nantong. No significant deviation from Hardy-Weinberg equilibrium was observed at all STR loci, and the expected heterozygosity ranged from 0.6184 to 0.9187. The combined match probability (CMP) was 3.87 × 10(-21), and the combined power of discrimination (CPD) was 99.999999999999999999613 %. No significant difference of allele frequencies was observed between Nantong and other Han populations at all STR loci, as well as Dai, Mongolian, and Tibetan. Significant differences were only observed between Nantong Han and Uyghur at TH01, as well as Nantong Han and Dong at CSF1PO and FGA. Nantong Han showed significant differences between She, Bouyei, and Miao at multiple STR loci. PMID:26932871

  8. Genetic Variation of 25 Y-Chromosomal and 15 Autosomal STR Loci in the Han Chinese Population of Liaoning Province, Northeast China

    Science.gov (United States)

    Yao, Jun; Wang, Bao-jie

    2016-01-01

    In the present study, we investigated the genetic characteristics of 25 Y-chromosomal and 15 autosomal short tandem repeat (STR) loci in 305 unrelated Han Chinese male individuals from Liaoning Province using AmpFISTR® Yfiler® Plus and IdentifilerTM PCR amplification kits. Population comparison was performed between Liaoning Han population and different ethnic groups to better understand the genetic background of the Liaoning Han population. For Y-STR loci, the overall haplotype diversity was 0.9997 and the discrimination capacity was 0.9607. Gene diversity values ranged from 0.4525 (DYS391) to 0.9617 (DYS385). Rst and two multi-dimensional scaling plots showed that minor differences were observed when the Liaoning Han population was compared to the Jilin Han Chinese, Beijing Han Chinese, Liaoning Manchu, Liaoning Mongolian, Liaoning Xibe, Shandong Han Chinese, Jiangsu Han Chinese, Anhui Han Chinese, Guizhou Han Chinese and Liaoning Hui populations; by contrast, major differences were observed when the Shanxi Han Chinese, Yunnan Bai, Jiangxi Han Chinese, Guangdong Han Chinese, Liaoning Korean, Hunan Tujia, Guangxi Zhuang, Gansu Tibetan, Xishuangbanna Dai, South Korean, Japanese and Hunan Miao populations. For autosomal STR loci, DP ranged from 0.9621 (D2S1338) to 0.8177 (TPOX), with PE distributing from 0.7521 (D18S51) to 0.2988 (TH01). A population comparison was performed and no statistically significant differences were detected at any STR loci between Liaoning Han, China Dong, and Shaanxi Han populations. The results showed that the 25 Y-STR and 15 autosomal STR loci in the Liaoning Han population were valuable for forensic applications and human genetics, and Liaoning Han was an independent endogenous ethnicity with a unique subpopulation structure. PMID:27483472

  9. Incidence of gastroesophageal reflux disease in Uygur and Han Chinese adults in Urumqi

    Institute of Scientific and Technical Information of China (English)

    Chun-Yan Niu; Yong-Li Zhou; Rong Yan; Ni-La Mu; Bao-Hua Gao; Fang-Xiong Wu; Jin-Yan Luo

    2012-01-01

    AIM:To investigate the incidence of gastroesophageal reflux disease (GERD) and its related risk factors in Uygur and Han Chinese adult in Urumqi,China.METHODS:A population-based cross-sectional survey was undertaken in a total of 972 Uygur (684 male and 288 female) aged from 24 to 61 and 1023 Han Chinese (752 male and 271 female) aged from 23 to 63 years.All participants were recruited from the residents who visited hospital for health examination from November 2011 to May 2012.Each participant signed an informed consent and completed a GERD questionnaire (Gerd Q) and a lifestyle-food frequency questionnaire survey.Participants whose Gerd Q score was ≥ 8 and met one of the following requirements would be enrolled into this research:(1) being diagnosed with erosive esophagitis (EE) or Barrett's esophagus (BE) by endoscopy; (2) negative manifestation under endoscopy (non-erosive reflux disease,NERD) with abnormal acid reflux revealed by 24-h esophageal pH monitoring; and (3) suffering from typical heartburn and regurgitation with positive result of proton pump inhibitor test.RESULTS:According to Gerd Q scoring criteria,340 cases of Uygur and 286 cases of Han Chinese were defined as GERD.GERD incidence in Uygur was significantly higher than in Han Chinese (35% vs 28%,x2 =11.09,P < 0.005),Gerd Q score in Uygur was higher than in Han Chinese (7.85 ± 3.1 w 7.15 ± 2.9,P < 0.005),and Gerd Q total score in Uygur male was higher than in female (8.15 ± 2.8 vs 6.85 ± 2.5,P <0.005).According to normalized methods,304 (31%) cases of Uygur were diagnosed with GERD,including 89 cases of EE,185 cases of NERD and 30 cases of BE; 256 (25%) cases of Han Chinese were diagnosed with GERD,including 90 cases of EE,140 cases of NERD and 26 cases of BE.GERD incidence in Uygur was significantly higher than in Han Chinese (31% vs 25%,x2=9.34,P < 0.005) while the incidences were higher in males of both groups than in females (26% vs 5% in Uygur,x2 =35.95,P < 0

  10. Association of the KLF14 rs4731702 SNP and serum lipid levels in the Guangxi Mulao and Han populations.

    Science.gov (United States)

    Huang, Ping; Yin, Rui-Xing; Huang, Ke-Ke; Zeng, Xiao-Na; Guo, Tao; Lin, Quan-Zhen; Wu, Jian; Wu, Dong-Feng; Li, Hui; Pan, Shang-Ling

    2013-01-01

    The objective of the present study was to detect the association of the rs4731702 single nucleotide polymorphism (SNP) and serum lipid levels in the Guangxi Mulao and Han populations. A total of 727 subjects of Mulao and 740 subjects of Han Chinese were included. Serum low-density lipoprotein cholesterol (LDL-C) and apolipoprotein (Apo) B levels were higher in Mulao than in Han (P KLF14 rs4731702 SNP and serum lipid levels between the two ethnic groups might partly result from different gene-environmental interactions. PMID:24195066

  11. Association of the KLF14 rs4731702 SNP and Serum Lipid Levels in the Guangxi Mulao and Han Populations

    OpenAIRE

    Ping Huang; Rui-Xing Yin; Ke-Ke Huang; Xiao-Na Zeng; Tao Guo; Quan-Zhen Lin; Jian Wu; Dong-Feng Wu; Hui Li; Shang-Ling Pan

    2013-01-01

    The objective of the present study was to detect the association of the rs4731702 single nucleotide polymorphism (SNP) and serum lipid levels in the Guangxi Mulao and Han populations. A total of 727 subjects of Mulao and 740 subjects of Han Chinese were included. Serum low-density lipoprotein cholesterol (LDL-C) and apolipoprotein (Apo) B levels were higher in Mulao than in Han (P < 0.05). The T allele carriers had higher serum LDL-C and ApoAI levels in Mulao, whereas they had lower high-dens...

  12. Hanxue Shangdui: A case study on the contentions between the Han School and the Song School in the middle Qing dynasty

    Institute of Scientific and Technical Information of China (English)

    Zhang Shuhong

    2006-01-01

    During the Jiaqing and Daoguang periods of the Qing dynasty,Fang Dongshu published the Hanxue Shangdui,which launched a fierce attack on the Han School and marked the open contentions between the Han and the Song schools.While defending the Song Learning.Fang attacked the shortcomings of the Han School.mainly in four aspects:the Han School's methods of scholarship,various concepts of philosophy proposed by the Han-Learning scholars,the trivial and piecemeal character,and the heterodoxy of the Han School.Fang Dongshu criticized the Han-Learning scholars who Paid attention only to the books and neglected the social affairs.Sharp and reasonable as it was,his criticism however seemed less objective,especially when he tried to use the emperor's authority to threaten the Han School,which was beyond the range of the normal academic debates.

  13. Receita pública e bem-estar social nos municípios mineiros emancipados no período de 1988 a 1997 Hacienda pública y bien estar social en los municipios de minas gerais emancipados en el periodo de 1988 a 1997 Revenue and social welfare in the emancipated municipalitiesof minas gerais during the periods of 1988 to 1997

    Directory of Open Access Journals (Sweden)

    Paulo Ricardo da Costa Reis

    2013-04-01

    Full Text Available O movimento de descentralizações política, administrativa e fiscal intensificado a partir de 1988 tinha como objetivo promover a transferência de poder, recursos e atribuições para os governos locais. Além disso, esse fenômeno impulsionou o processo de emancipação municipal com o intuito de aproximar o poder público da sociedade, promovendo a melhoria da prestação de serviços. Este estudo apresenta a análise das receitas públicas e do bem-estar social dos municípios mineiros emancipados no período de 1988 a 1997. Para tanto, utilizaram-se testes de médias no intuito de comparar o desempenho dos municípios emancipados com o desempenho de seus municípios de origem. Como conclusão, verificou-se que os novos municípios são beneficiados com as transferências governamentais e possuem a mesma capacidade de arrecadação tributária dos seus municípios de origem. Não obstante, isso não permitiu que os citados municípios apresentassem nível de bem-estar superior em relação aos municípios de origem, assim como maior eficiência na gestão desses recursos, uma vez que estão mais próximos dos usuários.El proceso de descentralización política, administrativa y fiscal intensificado a partir de 1988 tenía como objetivo promover la transferencia de poder, recursos y atribuciones para los gobiernos locales. Además, ese proceso ha impulsado el proceso de emancipación municipal de prestación de servicios. Este estudio presenta el análisis de las haciendas públicas y del bien estar social de los municipios de Minas Gerais emancipados en el periodo de 1988 a 1997. Para tanto, se han utilizado testes de medias con el objetivo de comparar el desempeño de los municipios emancipados con el desempeño de sus municipios de origen. Como conclusión, se ha verificado que los nuevos municipios son beneficiados con las transferencias gubernamentales y poseen la misma capacidad de recaudación tributaria de sus municipios de origen

  14. Quines empreses han aguantat millor la crisi, les empreses familiars o les no familiars?

    Directory of Open Access Journals (Sweden)

    Jose Luis Gallizo

    2014-12-01

    Full Text Available Objecte: En aquest estudi és porta a terme un anàlisi comparatiu sobre l’evolució de l’estructura econòmica i financera que presenten les empreses familiars i no familiars de Catalunya en un context d’intensa crisi econòmica. La seva finalitat és poder donar resposta a dos qüestions principals: identificar les característiques diferencials de l’EF respecte a l’EnF i comprovar si aquestes característiques diferencials han permès a les EF aguantar millor la crisi econòmica. Disseny/metodologia: S’ha analitzat una mostra de 750 grans i mitjanes empreses de Catalunya (550 familiars i 200 no familiars durant el període 2008-2012. Les dades s’han obtingut a través de la base de dades SABI, i per a la classificació de les empreses en familiars i no familiars s’ha dut a terme una comprovació individual de cadascuna d’elles per evitar habituals errors de classificació. Posteriorment les empreses s’han classificat en funció de la seva dimensió per dotar d’una major robustes els resultats. També s’ha procurat que la distribució d’empreses per sectors fos similar en les diferents categories per evitar que un efecte sectorial pogués tergiversar els resultats de l’estudi. Aportacions i resultats: L’estudi ha permès constatar les hipòtesis establertes sobre el finançament de les empreses familiars i concloure que aquestes presenten una estructura financera diferent a les Empreses no familiars. Les empreses familiars als seus balanços, presenten un major nivell d’autofinançament gràcies a la seva menor distribució de dividends. A més a més, les EF presenten millors resultats en quant a nivells de cobertura i liquiditat, ja que es troben més capitalitzades i presenten uns nivells d’endeutament inferior que les Empreses no familiars. Aquestes característiques patrimonials i financeres han contribuït a que les empreses familiars aguantin millor els anys de crisi, produint-se durant aquests anys

  15. Review: Hans Eric Stolten (ed.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa (2007) Buchbesprechung: Hans Eric Stolten (Hrsg.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa (2007)

    OpenAIRE

    Rita Schäfer

    2009-01-01

    Review of the edited volume: Hans Eric Stolten (ed.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa, Uppsala: Nordic Africa Institute 2007, ISBN 978-91-7106-581-0, 376 pages. Besprechung des Sammelbandes: Hans Eric Stolten (Hrsg.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa, Uppsala: Nordic Africa Institute 2007, ISBN 978-91-7106-581-0, 376 Seiten.

  16. FACTORES DE ÉXITO EN PROVEEDORES DE BIENES MANUFACTURADOS DE LA SALMONICULTURA CHILENA SUCCESS FACTORS IN SUPPLIERS OF MANUFACTURES WITHIN THE CHILEAN SALMON INDUSTRY

    Directory of Open Access Journals (Sweden)

    Carlos Torres Fuchslocher

    2009-04-01

    Full Text Available Este artículo analiza, en base a un trabajo empírico, los principales factores a nivel de la empresa que han determinado el éxito de los proveedores locales de manufacturas, en términos de participación de mercado, en el cluster del salmón en Chile. La investigación envolvió un levantamiento de material empírico a través de 50 entrevistas, las cuales fueron evaluadas cualitativamente y por medio de un análisis econométrico de corte transversal, usando variables explicativas cualitativas. Los resultados destacan la especialización sectorial, la innovación en productos especializados para la industria y la cooperación horizontal, dentro de la estrategia de entrada; y la antigüedad de la empresa, la capacidad de innovación interna, la capacidad financiera (capacidad de otorgar crédito a clientes y bajo nivel de endeudamiento y la diversificación de la cartera productos, dentro de la competitividad previa, como determinantes del éxito de los proveedores.This article analyses the main factors at the firm-level which have determined the success, in terms of market share, of manufacture suppliers within the Chilean salmon industry. The analysis is based on data collected in an empirical research that included 50 interviews with suppliers. The data was evaluated through both a qualitative analysis and a cross section econometric analysis. The results show the importance of sectoral specialization, the innovation on specialized products for the aquaculture industry and horizontal cooperation within the entry strategy of firms, whereas the firm's age, the internal innovation capabilities, the own capital and the diversification of product portfolio were the main competitive factors before the entry.

  17. Comer bien, comer mal: la medicalización del comportamiento alimentario Eating well, eating poorly and the medicalization of eating behavior

    Directory of Open Access Journals (Sweden)

    Mabel Gracia-Arnaiz

    2007-06-01

    Full Text Available En este artículo se analiza el progresivo proceso de medicalización del comportamiento alimentario por el cual una buena parte de los motivos pragmáticos o simbólicos que articulan la selección y el consumo humano de alimentos se ha sustituido por otros de orden nutricional. La normalización dietética se ha concretado, en particular en los contextos de relativa abundancia de alimentos, en torno de la dieta equilibrada, un patrón alimentario basado en la restricción y promoción del consumo de ciertos alimentos y nutrientes -qué y cuánto comer- y en la prescripción de un conjunto de pautas relativas a cómo, cuándo y con quién hacerlo, y cuyos objetivos han sido no sólo regular los cuidados del cuerpo y la salud, sino promover, a su vez, un cierto orden social y ético.This article describes how the progressive process of medicalization of food is inscribed within a biomedical logic that attempts to substitute many of the economic, adaptative and symbolic reasons that have ethnographically and historically conditioned eating habits in all cultures, exclusively for reasons of a dietetic nature. According to this logic, most of the population of modern societies does not know how to eat because they are victims of or have been made ill by the current profusion of food. They must, therefore, learn how to eat well, which in terms of eating practices means eating a little of everything, in moderation and in a balanced way. The main aim of current nutritional education is to (reestablish a supposed dietetic normality as far as food consumed, quantities, number of intakes and meal structures are concerned.

  18. La etapa de los bienes globales en salud, una perspectiva nacional The age of public goods in health, a national perspective

    Directory of Open Access Journals (Sweden)

    José Ángel Córdova-Villalobos

    2008-01-01

    Full Text Available Los efectos adversos del tabaquismo sobre la salud han sido ampliamente reconocidos desde tiempo atrás. A pesar de todo, el tabaquismo no parece disminuir, con las inevitables consecuencias sobre la morbilidad y la mortalidad de millones de personas. Tan sólo en este año la OMS calcula que cinco millones de personas morirán por esta causa. En México, 26.2% de la población entre 15 y 65 años fuma con regularidad y el consumo se incrementa entre los jóvenes y las mujeres. La OMS adoptó el Convenio Marco para el Control del Tabaco, ratificado por México, lo que llevó a la creación de la Ley General para el Control del Tabaco, un importante hito en la política sanitaria mexicana, que próximamente será promulgada y que se espera tendrá un efecto notable en la contención de la epidemia de tabaquismo en el país.Adverse health effects from smoking have been widely known for a long time. Nevertheless, tobacco use does not appear to decrease, and with it the inevitable consequences on morbidity and mortality for millions of people continue. This year alone, the WHO calculates that five million people will die from tobacco use. In Mexico, 26.2% of the population between the ages of 15 and 65 smoke regularly and consumption increases among youth and women. The WHO adopted the Framework Convention on Tobacco Control, ratified by Mexico, which brought about the General Law for Tobacco Control, an important milestone in Mexican sanitary policy. This law will soon be in force and is expected to have a notable effect on containing the smoking epidemic in the country.

  19. Review: Hans Eric Stolten (ed.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa (2007)

    OpenAIRE

    Rita Schäfer

    2009-01-01

    Review of the edited volume: Hans Eric Stolten (ed.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa, Uppsala: Nordic Africa Institute 2007, ISBN 978-91-7106-581-0, 376 pages.

  20. Buchbesprechung: Hans Eric Stolten (Hrsg.): History making and present day politics. The meaning of collective memory in South Africa (2007)

    OpenAIRE

    Schäfer, Rita

    2009-01-01

    Review of the edited volume: Hans Eric Stolten (ed.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa, Uppsala: Nordic Africa Institute 2007, ISBN 978-91-7106-581-0, 376 p.

  1. Association of TSHR gene polymorphisms and haplotypes with Graves’ disease in Han population from coastal areas in Shandong province

    Institute of Scientific and Technical Information of China (English)

    王海丽

    2013-01-01

    Objective To investigate the association of thyroid stimulating hormone receptor(TSHR)gene polymorphisms and haplotypes with Graves’disease(GD)in Han population from coastal areas in Shandong province

  2. Sequence analysis and functional study of the Han Nationality glial cell line-derived neurotrophic factor transcript

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhe-yu; HUANG Ai-jun; LU Chang-lin; WU Xiang-fu; HE Cheng

    2001-01-01

    To study the sequence and function of the glial cell line-derived neurotrophic factor (GDNF) transcript in subjects of Han nationality. Methods: The Han nationality GDNF transcript was amplified by RT-PCR and expressed by baculovirus expression system. Biological activity of the expressed product was measured by the primary culture of midbrain dopaminergic neurons. Results: There only existed the shorter GDNF transcript of 555 bp in the Han nationality. The secretory expression product of the shorter transcript in insect cells promoted the survival and differentiation of dopaminergic neurons. Conclusion: It is found that there is a 78 bp deletion in the Han nationality GDNF transcript compared with the reported 633 bp GDNF transcript. The 78 bp deletion does not affect the secretory expression and biological activity of GDNF mature protein.

  3. Factor analysis and cluster analysis applied to assess the water quality of middle and lower Han River in Central China

    Science.gov (United States)

    Kuo, Yi-Ming; Liu, Wen-Wen

    2015-04-01

    The Han River basin is one of the most important industrial and grain production bases in the central China. A lot of factories and towns have been established along the river where large farmlands are located nearby. In the last few decades the water quality of the Han River, specifically in middle and lower reaches, has gradually declined. The agricultural nonpoint pollution and municipal and industrial point pollution significantly degrade the water quality of the Han River. Factor analysis can be applied to reduce the dimensionality of a data set consisting of a large number of inter-related variables. Cluster analysis can classify the samples according to their similar characters. In this study, factor analysis is used to identify major pollution indicators, and cluster analysis is employed to classify the samples based on the sample locations and hydrochemical variables. Water samples were collected from 12 sample sites collected from Xiangyang City (middle Han River) to Wuhan City (lower Han River). Correlations among 25 hydrochemical variables are statistically examined. The important pollutants are determined by factor analysis. A three-factor model is determined and explains over 85% of the total river water quality variation. Factor 1, including SS, Chl-a, TN and TP, can be considered as the nonpoint source pollution. Factor 2, including Cl-, Br-, SO42-, Ca2+, Mg2+, K+, Fe2+ and PO43-, can be treated as the industrial pollutant pollution. Factor 3, including F- and NO3-, reflects the influence of the groundwater or self-purification capability of the river water. The various land uses along the Han River correlate well with the pollution types. In addition, the result showed that the water quality of Han River deteriorated gradually from middle to lower Han River. Some tributaries have been seriously polluted and significantly influence the mainstream water quality of the Han River. Finally, the result showed that the nonpoint pollution and the point

  4. Novi Han Radioactive Waste Repository post-closure safety assessment, ver.2

    International Nuclear Information System (INIS)

    The methodology for the post-closure safety assessment is presented. The assessment context includes regulatory framework (protection principles); scope and time frame; radiological and technical requirements; modeling etc. The description of the Novi Han disposal system contains site location. meteorological, hydrological and seismological characteristics; waste and repository description and human activities characteristics. The next step in the methodology is scenario development and justification. The systematic generation os exposure scenarios is considered as central to the post-closure safety assessment. The most important requirements for the systematic scenario generation approach are: transparency, comprehensiveness (all possible FEPs influencing the the disposal system and the radionuclide release should be considered); relevant future evolutions; identification of critical issues and investigation of the robustness of the system. For the source-pathway-receptor analysis the Process System is divided into near-field, geosphere/atmosphere and biosphere, describing the key facets controlling the potential radionuclide migration to the environment. The schematic division of the Novi Han near-field Process System into lower-level conceptual features is presented and discussed. As a result of the examinations of the FEPs three classes of scenarios are identified for the Novi Han post-closure safety assessment: Environmental evolution scenarios (geological change and climate change); future human action scenarios (human intrusion and archaeological action); Scenarios with very low probability (terrorism, crashes, explosions). The safety assessment iteration leads to identification of a modern scenario generation approach, assessment of key radionuclide releases, geological and hydrological evaluation, identification of the key parameters from sensitivity analysis etc. Examples of conceptual models are given. For the mathematical modeling the AMBER code is used

  5. Association study of ankylosing spondylitis and polymorphisms in ERAP1 gene in Zhejiang Han Chinese population.

    Science.gov (United States)

    Liu, Yangbo; Li, Liangda; Shi, Shanfen; Chen, Xin; Gao, Jianqing; Zhu, Minyu; Yuan, Jiandong

    2016-02-01

    The susceptibility loci of ERAP1 polymorphisms have been found to be strongly associated with ankylosing spondylitis (AS). The researches in multiple ethnic cohorts suggested that the population attributable risk in ERAP1 polymorphisms is at a high significance level. This study was undertaken to estimate the prevalence and incidence of subsets of AS and investigate the specific variants of ERAP1 polymorphisms in AS susceptibility, in the Han ethnic Chinese population in Zhejiang Province. AS patients were selected, diagnosed, and confirmed by a qualified rheumatologist. The basal clinical and demographic characteristics were compared with all subjects. Genotypes for eight selected single nucleotide polymorphisms (SNPs) in ERAP1 gene (rs27038, rs27037, rs27434, rs27980, rs7711564, rs30187, rs10050860, and rs17482078) were determined by using the Sequenom MassARRAY iPLEX platform in Zhejiang Han Chinese population. Association analyses were performed on the whole genotyped data set in 707 unrelated ankylosing spondylitis cases and 837 ethnically matched controls. We observed the strongest association between AS and HLA-B27, which confers over 90 % of ankylosing spondylitis cases. Moreover, we found three loci of ERAP1 polymorphisms were at a high significance level (rs27037 P = 0.00451; rs27434 P = 0.00012; rs27980 P = 0.00682) with AS in Zhejiang population. We also confirmed polymorphism locus of ERAP1 previously reported association with AS (rs27434; P = 5.3 × 10(-12)). Our results indicated a difference in the mechanism of susceptibility loci in subsets of Zhejiang Han Chinese population and provided further evidence that rs27434 is the key polymorphism associated with AS in ERAP1 gene. PMID:26350268

  6. Environmental Risk Factors in Han and Uyghur Children with Dyslexia: A Comparative Study.

    Directory of Open Access Journals (Sweden)

    Hua Zhao

    Full Text Available Several studies have been conducted to explore risk factors for dyslexia. However, most studies examining dyslexia have been skewed toward Western countries, and few have considered two nationalities simultaneously. This study focused on differences in dyslexia prevalence and potential environmental risk factors between Han and Uyghur children.A cross-sectional study was conducted in Kashgar and Aksu, cities in Xinjiang province, China. A two-stage sampling strategy was used to recruit 2,854 students in grades 3-6 from 5 primary schools in 5 districts; 2,348 valid student questionnaires were included in the analysis. Dyslexia checklists for Chinese and Uyghur children and pupil rating scales were used to identify children with dyslexia. Questions related to the home literacy environment and reading ability were used to evaluate potential environmental risk factors. Single factor analysis and multivariate logistic regression were used to examine prevalence and risk factors for dyslexia.Dyslexia prevalence differed significantly between Han (3.9% and Uyghur (7.0% children (P < 0.05, and the boy-to-girl diagnosis ratio was almost 2:1. Multiple logistic regression analysis showed that ethnic differences in dyslexia prevalence between Han and Uyghur children could have occurred because of factors such as mother's occupation (P = 0.02, OR = 0.04, 95% CI = 0.01-0.68 and the frequency with which parents told stories (P = 0.00, OR = 4.50, 95% CI = 1.67-12.11.The prevalence of dyslexia was high in all children, particularly those in the Uyghur group. Environmental factors could have been responsible for some of the differences observed. The results contribute to the early identification and management of dyslexia in children from these two groups and research examining developmental dyslexia and differences in racial genetics.

  7. Vitamin D binding protein variants associate with asthma susceptibility in the Chinese han population

    Directory of Open Access Journals (Sweden)

    Zhang Youming

    2011-08-01

    Full Text Available Abstract Background Asthma is a genetically heterogeneous disease. Polymorphisms of genes encoding components of the vitamin D pathway have been reported to associate with the risk of asthma. We have previously demonstrated that vitamin D status was associated with lung function in Chinese asthma patients. In this study, we tested whether polymorphisms of genes encoding for vitamin D receptor (VDR, vitamin D 25-hydroxylase (CYP2R1 and vitamin D binding protein (GC were associated with asthma in the Chinese Han population. Methods We sequenced all 8 exons of VDR and all 5 exons of CYP2R1 in a Chinese case-control cohort of asthma consisting of 467 cases and 288 unrelated healthy controls. Two mutations were identified in these regions. These variants were specified as rs2228570 in exon 2 of VDR and rs12794714 in exon 1 of CYP2R1. We also genotyped two common polymorphisms in GC gene (rs4588 and rs7041 by a PCR-restriction fragment length polymorphism (RFLP method. We analyzed the association between these 4 polymorphisms and asthma susceptibility and asthma-related traits. Results Polymorphic markers in VDR and CYP2R1 were not associated with asthma in the Chinese Han cohort. Importantly, variants in GC gene, which give rise to the two most common electrophoretic isoforms of the vitamin D binding protein, were associated with asthma susceptibility. Compared with isoform Gc1, Gc2 was significantly associated with the risk of asthma (OR = 1.35, 95% CI = 1.01-1.78 p = 0.006. Conclusions The results provide supporting evidence for association between GC variants and asthma susceptibility in the Chinese Han population.

  8. Variation in STAT4 is associated with systemic lupus erythematosus in Chinese Northern Han population

    Institute of Scientific and Technical Information of China (English)

    SU Yin; SONG Hui; HUANG Ci-bo; HUANG Yan-hong; WANG Tian; PAN Si-si; LI Chun; LIU Xia; ZHU Lei; ZHANG Chun-fang; LI Zhan-guo; ZHAO Yi; LIU Xu; GUO Jian-ping; JIANG Quan; LIU Xiang-yuan; ZHANG Feng-chun; ZHENG Yi; LI Xiao-xia

    2010-01-01

    Background Recent studies have identified signal transducer and activator of transcription 4 (STAT4) as a susceptibility gene for systemic lupus erythematosus (SLE) in different populations. In order to examine whether the allele distribution of the single nucleotide polymorphism (SNP) in gene STAT4 rs7574865 in patients with SLE is different from those of healthy controls in Chinese Northern Han population, we investigated whether the variants of STAT4 rs7574865 were associated with any specific clinical features of SLE.Methods We genotyped SNPs in STAT4 rs7574865 in 252 patients with SLE and 497 healthy controls. All subjects were from the Northern part of Chinese Han population. The genotypes in rs7574865 were determined by polymerase chain reaction (PCR) and consequence direct sequencing of PCR products in the DNA samples.Results There was a significant difference in distribution of the SNPs in rs7574865 between the SLE patients and healthy controls. Compared with healthy controls, there was a significant correlation between ∏ genotypes in rs7574865 and the risk of SLE when GG genotype was used as a reference genotype after adjusting for gender and age. The frequency of T allele in the SLE patients was strongly significantly higher than that of healthy controls. Furthermore, there was a significant difference in the distribution of SNP in rs7574865 between male and female SLE patients, when compared with healthy controls. The frequency of T allele in rs7574865 in male patients was significantly higher than that of male healthy controls or female patients. There was no significant correlation between the frequencies of T allele in STAT4 rs7574865 and the clinical features of SLE.Conclusions The SNP rs7574865 in STAT4 is strongly associated with risk of SLE in the Chinese Northern Han population. The ∏ genotype and T allele in STAT4 rs7574869 are susceptibility factors for SLE, especially for male SLE patients.

  9. Association Study of IL-12B Polymorphisms Susceptibility with Ankylosing Spondylitis in Mainland Han Population.

    Directory of Open Access Journals (Sweden)

    Li Zhang

    Full Text Available This study aims to determine whether the genetic polymorphisms of IL-12B gene is a susceptibility factor to Ankylosing spondylitis (AS in mainland Han Chinese population.Eight single-nucleotide polymorphisms (SNPs (rs10045431, rs11167764, rs3212227, rs6556412, rs6556416, rs6871626, rs6887695 and rs7709212 in the IL-12B gene were genotyped by iMLDR Assay technology in 400 patients [96% (384/400 HLA-B27(+] and 395 geographically and ethnically matched healthy controls in mainland Han Chinese population. The correlation between IL-12B genetic polymorphisms and AS activity index (BASDAI, BASFI were tested.The significant difference was found in genotype distribution between AS and healthy controls (χ2 = 6.942, P-value = 0.031 of the SNP rs6871626. Furthermore, significant evidence was also detected under the recessive model for minor allele A. The AA genotype carrier had 1.830 fold risk compared with C allele carrier (with CC and AC genotypes [OR (95% CI = 1.830 (1.131-2.961, P-value = 0.014]. Nevertheless, the difference was no longer significant after Bonferroni correction. Subset analysis on cases with HLA-B27(+ did find the same results. Three genotypic groups (AA, CC and CA in rs6871626 site was highly associated with the BASDAI and BASFI (P-value = 0.012 and P-value = 0.023, respectively, after adjustment for effect of age, sex, and disease duration, the P-value was 0.031 and 0.041, respectively. The AA genotype of rs6871626 was also significantly correlated with an increased BASDAI and BASFI compared to the AC and CC genotypes in AS patients.Our findings suggest that rs6871626 may be associated AS susceptibility and with disease activity (BASDAI, BASFI in mainland Han Chinese population.

  10. The association between common genetic variation in the FTO gene and metabolic syndrome in Han Chinese

    Institute of Scientific and Technical Information of China (English)

    WANG Tong; ZHANG Li-li; ZHANG Yun; SUN Xiao-fang; ZHANG Qian; HUANG Yi; XIAO Xin-hua; WANG Duen-mei; DIAO Cheng-ming; ZHANG Feng; XU Ling-ling; ZHANG Yong-biao; LI Wen-hui

    2010-01-01

    Background Genome-wide association studies for type 2 diabetes mellitus (T2DM) identified FTO gene as a locus conferring increased risk for common obesity in many populations with European ancestry. However, the involvement of FTO gene in obesity or T2DM related metabolic traits has not been consistently established in Chinese populations. The objective of this study was to investigate the association of FTO genetic polymorphisms with metabolic syndrome (MetS) in Han Chinese.Methods We tested 41 FTO single nucleotide polymorphisms (SNPs) for association between FTO and MetS-related traits. There were a total of 236 unrelated subjects (108 cases and 128 controls), grouped according to the International Diabetes Federation (IDF) criteria.Results Of the 41 SNPs examined, only SNP rs8047395 exhibited statistical significance (P=0.026) under a recessive model, after Bonferroni adjustment for multiple testing (OR 1.64, 95% CI 1.11-2.42; P=0.014). The common distributions of this polymorphism among Chinese-with a minor allele frequency (MAF) of 36% in the control group versus 48% in the MetS group-greatly improved our test power in a relatively small sample size for an association study. Previously identified obesity-(or T2DM-) associated FTO SNPs were less common in Han Chinese and were not associated with MetS in this study. No significant associations were found between our FTO SNPs and any endophenotypes of MetS.Conclusions A more common risk-conferring variant of FTO for MetS was identified in Han Chinese. Our study substantiated that genetic variations in FTO locus are involved in the pathogenesis of MetS.

  11. Clinical analysis of intraoperative radiotherapy during breast-conserving surgery of early breast cancer in the Chinese Han population

    OpenAIRE

    Xin WANG; Liu, Jiaqi; Wang, Wenyan; Feng, Qinfu; Wang, Xiang

    2015-01-01

    Purpose While results of intraoperative radiotherapy (IORT) during breast-conserving surgery (BCS) have been reported when used either as a boost at the time of surgery or as the sole radiation treatment, the clinical safety and cosmetic outcome of IORT in the Chinese Han population has not. This report reviews oncologic and cosmetic outcomes for Chinese Han breast cancer patients who received IORT either as a boost or as their sole radiation treatment at our hospital. Method From July 2008 t...

  12. Analysis of the genotype of diacylglycerol kinase delta single-nucleotide polymorphisms in Parkinson disease in the Han Chinese population

    OpenAIRE

    Wei Song; Yong Ping Chen; Rui Huang; Ke Chen; Ping Lei Pan; Jianpeng Li; Yuan Yang; Hui-Fang Shang

    2012-01-01

    Numerous Single-Nucleotide Polymorphisms (SNPs) of the Diacylglycerol Kinase Delta (DGKD) isoform 1 gene have been associated with Parkinson Disease (PD) in the genome-wide association studies of Caucasian population. This association has not been proven in the Han Chinese PD patients. This study included 376 unrelated Han Chinese PD patients from West China and 273 unrelated healthy controls from the same region. Five SNPs (rs2971859, rs1550532, rs2305539, rs2034762, and rs2242102) were geno...

  13. Hans Küng se voorstel vir ’n eietydse etiek

    Directory of Open Access Journals (Sweden)

    S. A. Strauss

    1998-06-01

    Full Text Available This contribution undertakes a critical assessment of the well-known Hans Küng's proposal for contemporary ethics in his book Global responsibility. In search of a new world ethic (1990. This article commences by providing some background on this publication as well as on the theology of Küng in general. The content of the book is then paraphrased in summarised form. The last part of the article analyses four major convictions of Kung, against which the Reformed doctrine is brought forward. These convictions deal with the ethical aspects of normativity, humanity, postmodernity and ecumenicity.

  14. The Life and Works of Han Shin Gwang : a Midwife and Nurse of Korean Modern Times

    OpenAIRE

    YI Ggodme

    2006-01-01

    Han Shin Gwang, born in an early Christian family in Korea in 1902, could get western education different from the ordinary Korean girls in that period. She participated in the 1919 Samil Independence Movement in her teens, and got nursing and midwifery education in a missionary hospital. She got a midwife license and worked as a member in an early mother-and-child health center. She organized 'Korean Nurses' Association' in 1924 and focused on public health movement as the chairwoman. She ac...

  15. Glaciological and chemical studies on ice cores from Hans Tausen ice cap, Greenland

    DEFF Research Database (Denmark)

    Clausen, H.B.; Stampe, Mia; Hammer, C.U.;

    2001-01-01

    The paper presents studies of various chemical and isotopical parameters from ice cores drilled in the northernmost located ice cap, Hans Tausen Iskappe, Pearyland, Greenland (HT). The 346 m main core (MC95) was drilled to bedrock in 1995 as well as a 35 m shallow core (SC95). A 60 m shallow core...... selected for an analysis of dust and water soluble chemical components, including F-, CH3SO2-, Cl-, NO3-, SO42-, Na+, NH4+, K+, Mg2+ and Ca2+. Coulter counter technique was used for the dust measurements and the chemical analysis were carried out by ion chromatography....

  16. HANS BELLMER, UN ARTISTE PHILOSOPHE OU L'IDENTITE EN QUESTION

    Directory of Open Access Journals (Sweden)

    MARYVONNE PERROT

    2013-05-01

    Full Text Available If the surrealist group has attracted the interest of philosophers, one can also note that some of these artists have attempted to develop their own philosophical reflection. This was the case of Hans Bellmer obsessed with the themes of desire, body and metamorphosis and, through that, with the games of identity and otherness. The anatomy of the image, one of Bellmer’s essential books, also shows the role of the artistic creation in the efforts to illuminate the “enigma of existence”.

  17. NO ASSOCIATION BETWEEN TUMOR NECROSIS FACTOR ALPHA AND OBSESSIVE COMPULSIVE DISORDER IN CHINESE HAN POPULATION

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Objective To investigate association between tumor necrosis factor alpha (TNF-α) and obsessive compulsive disorder (OCD) in Chinese Han population.Methods Plasma concentrations of TNF-α were measured in 61 drug-free patients who fulfilled DSM-Ⅳ criteria for OCD and 93 healthy controls.TNF-α concentrations in blood were determined by enzyme-linked immunosorbent assay (ELISA).Two polymorphisms of TNF-α gene were investigated in the same patients and healthy controls:-308 G/A and-238 G/A.The allelic and genoty...

  18. Ethos kantiano e funcionalização da história em Hans Blumenberg

    OpenAIRE

    Feron, Olivier

    2015-01-01

    O historicismo assumido por Hans Blumenberg foi, muitas vezes, interpretado como método aplicado à história da filosofia, sobretudo sua análise dos tempos modernos. O presente artigo propõe uma leitura complementar que faz dessa fenomenologia histórica a expressão de uma prática ética da filosofia que, apesar da desconstrução do conceito de teleologia, encontra em Kant sua inspiração prática.

  19. Narrative Angle of Han Music Collection%汉乐府的叙事角度

    Institute of Scientific and Technical Information of China (English)

    谈艺超

    2012-01-01

    The first-person and the third-person narrative angles are applied in the narrative poems in Han Music Collection. The different narrative angle produces the different aesthetic effect.%汉乐府叙事诗所采用的叙事角度多为第一人称及第三人称叙事视角,也有不少作品根据情节设置的需要转换视角,不同的叙事角度产生不同的审美效果。

  20. Associations Between ABCG2 Gene Polymorphisms and Isolated Septal Defects in a Han Chinese Population

    OpenAIRE

    Wang, Chuan; Xie, Liang; Li, Huaying; Li, Yifei; Mu, Dezhi; Zhou, Rong; Liu, Ruiqi; Zhou, Kaiyu; Hua, Yimin

    2014-01-01

    Breast cancer resistance protein (BCRP) in the placenta, encoded by the ABCG2 gene in humans, plays an essential role in regulating fetal exposure to toxicants and the maintenance of cellular folic acid homeostasis. This study aimed at exploring the associations between 421C>A and 34G>A polymorphisms within the ABCG2 gene of the children and isolated septal defects in a Han Chinese population. An age- and gender-matched case-control study involving 210 pairs was conducted. Genotyping of the A...

  1. Ein Frankfurter Physiker, der die Welt veränderte : Hans Albrecht Bethes bewegtes Leben

    OpenAIRE

    Schmidt-Böcking, Horst (Prof. Dr.)

    2008-01-01

    Der Nobelpreisträger Hans Albrecht Bethe war einer der ganz großen Physiker des 20. Jahrhunderts. Er gilt als einer der Väter der modernen Quantenphysik. In seiner Bedeutung für die Entwicklung der modernen Physik kommt er selbst Werner Heisenberg oder Max Planck sehr nahe. Er ist in Frankfurt aufgewachsen, hat hier das Goethe-Gymnasium besucht und an der Universität Frankfurt studiert. 1933 musste er emigrieren, da seine Mutter jüdischen Glaubens war. In seiner Heimatstadt Frankfurt ist er b...

  2. Mitochondrial DNA Haplogroups and the Risk of Sporadic Parkinson's Disease in Han Chinese

    Institute of Scientific and Technical Information of China (English)

    Ya-Fang Chen; Wan-Jin Chen; Xiao-Zhen Lin; Qi-Jie Zhang; Jiang-Ping Cai; Chia-Wei Liou; Ning Wang

    2015-01-01

    Background:Mitochondrial dysfunction is linked to the pathogenesis of Parkinson's disease (PD).However,the precise role of mitochondrial DNA (mtDNA) variations is obscure.On the other hand,mtDNA haplogroups have been inconsistently reported to modify the risk of PD among different population.Here,we try to explore the relationship between mtDNA haplogroups and sporadic PD in a Han Chinese population.Methods:Nine single-nucleotide polymorphisms,which define the major Asian mtDNA haplogroups (A,B,C,D,F,G),were detected via polymerase chain reaction-restriction fragment length polymorphism or denaturing polyacrylamide gel electrophoresis in 279 sporadic PD patients and 510 matched controls of Han population.Results:Overall,the distribution ofmtDNA haplogroups did not show any significant differences between patients and controls.However,after stratification by age at onset,the frequency of haplogroup B was significantly lower in patients with early-onset PD (EOPD) compared to the controls (odds ratio [OR] =0.225,95% confidence interval [CI]:0.082-0.619,P =0.004),while other haplogroups did not show significant differences.After stratification by age at examination,among subjects younger than 50 years of age:Haplogroup B also showed a lower frequency in PD cases (OR =0.146,95% CI:0.030-0.715,P =0.018) while haplogroup D presented a higher risk of PD (OR =3.579,95% CI:1.112-11.523,P =0.033),other haplogroups also did not show significant differences in the group.Conclusions:Our study indicates that haplogroup B might confer a lower risk for EOPD and people younger than 50 years in Han Chinese,while haplogroup D probably lead a higher risk of PD in people younger than 50 years of age.In brief,particular Asian mtDNA haplogroups likely play a role in the pathogenesis of PD among Han Chinese.

  3. Traduire la bêtise. Entretien avec Hans-Horst Henschen

    Directory of Open Access Journals (Sweden)

    Hans-Horst Henschen

    2012-03-01

    Full Text Available Quand il entreprend de traduire l’ensemble du corpus Bouvard et Pécuchet, Hans-Horst Henschen est déjà un traducteur reconnu. Ses traductions et/ou éditions de Barthes, Lévi-Strauss, Lyotard, Althusser, Michel Serres ou Jean Starobinski font de lui en Allemagne un relais important de la pensée française. Et à ces traductions d’auteurs ou de courants critiques, s’ajoutent celles qui s’y rattachent par raccroc ; celles qui semblent au contraire quitter les champs de l’anthropologie, de la psych...

  4. Between Looking and Making: Unravelling Dom Hans van der Laan’s Plastic Number

    OpenAIRE

    Caroline Voet

    2016-01-01

    Between 1920 and 1991, the Dutch Benedictine monk and architect Dom Hans van der Laan (1904–91) developed his own proportional system based on the ratio 3:4, or the irrational number 1.3247. . ., which he called the plastic number. According to him, this ratio directly grew from discernment, the human ability to differentiate sizes, and as such would be an improvement over the golden ratio. To put his theories to the test, he developed an architectural language, which can best be described as...

  5. [Which ethics for medical ethics? Homage to Hans Jonas, 1903-1993].

    Science.gov (United States)

    Munzarová, Marta

    2014-01-01

    Hans Jonas, one of the greatest philosophers of the 20th century, devoted several studies to the ethics in context with medicine and/or to the new biomedical research. His main thoughts in this field are presented (death and dying, mortality, reflections on experimenting with human subjects - nontherapeutic research, cloning, chimaeras). He was a man of wisdom and his humanity and moral sensibility are a matter of admiration. His ethics is in full consent with ethics and the dignity of medical profession. His ideas are compared (and contrasted) with those of the new bio"ethics". PMID:25370772

  6. Mitochondrial DNA haplogroup associated with sperm motility in the Han population

    OpenAIRE

    Guo-fang FENG; Jing ZHANG; Feng, Li-Min; Shen, Nai-Xian; Li, Le-jun; Zhu, Yi-Min

    2013-01-01

    In this study, we aimed to determine whether the main mitochondrial DNA (mtDNA) haplogroups of the Han people have an impact on spermatozoa motility. We recruited 312 men who were consecutively admitted to two affiliated hospitals of College of Medicine, Zhejiang University from May 2011 to April 2012 as part of fertility investigations. Semen and whole blood samples were collected from the men. We determined the mtDNA haplogroups by analysing the sequences of mtDNA hypervariable segment I an...

  7. Quantitative candidate gene association studies of metabolic traits in Han Chinese type 2 diabetes patients.

    Science.gov (United States)

    Wei, F J; Cai, C Y; Yu, P; Lv, J; Ling, C; Shi, W T; Jiao, H X; Chang, B C; Yang, F H; Tian, Y; Li, M S; Wang, Y H; Zou, L; Shi, J M; Chen, L M; Li, W D

    2015-01-01

    Recent genome-wide association studies have identified many loci associated with type 2 diabetes mellitus (T2DM), hyperuricemia, and obesity in various ethnic populations. However, quantitative traits have been less well investigated in Han Chinese T2DM populations. We investigated the association between candidate gene single nucleotide polymorphisms (SNPs) and metabolic syndrome-related quantitative traits in Han Chinese T2DM subjects. Unrelated Han Chinese T2DM patients (1975) were recruited. Eighty-six SNPs were genotyped and tested for association with quantitative traits including lipid profiles, blood pressure, body mass index (BMI), serum uric acid (SUA), glycated hemoglobin (HbA1c), plasma glucose [fasting plasma glucose (FPG)], plasma glucose 120 min post-OGTT (P2PG; OGTT = oral glucose tolerance test), and insulin resistance-related traits. We found that CAMTA1, ABI2, VHL, KAT2B, PKHD1, ESR1, TOX, SLC30A8, SFI1, and MYH9 polymorphisms were associated with HbA1c, FPG, and/or P2PG; GCK, HHEX, TCF7L2, KCNQ1, and TBX5 polymorphisms were associated with insulin resistance-related traits; ABCG2, SLC2A9, and PKHD1 polymorphisms were associated with SUA; CAMTA1, VHL, KAT2B, PON1, NUB1, SLITRK5, SMAD3, FTO, FANCA, and PCSK2 polymorphisms were associated with blood lipid traits; CAMTA1, SPAG16, TOX, KCNQ1, ACACB, and MYH9 polymorphisms were associated with blood pressure; and UBE2E3, SPAG16, SLC2A9, CDKAL1, CDKN2A/B, TCF7L2, SMAD3, and PNPLA3 polymorphisms were associated with BMI (all P values <0.05). Some of the candidate genes were associated with metabolic and anthropometric traits in T2DM in Han Chinese. Although none of these associations reached genome-wide significance (P < 5 x 10(-8)), genes and loci identified in this study are worthy of further replication and investigation. PMID:26634513

  8. Detecting the polymorphism sites of p53 and Fas genes of Han population in Zhejiang province

    Institute of Scientific and Technical Information of China (English)

    Yang Zhuo; Xingye Zeng; Dadao Huang; Xuexue Zhou

    2006-01-01

    BACKGROUND: It is of significance for single nucleotide polymorphisms (SNPs),a difference of rank, which exists widely in biology, genetics and other fields.OBJECTIVE: To detect polymorphism sites in exon-4 of p53 gene, promotor of Fas gene and intron-7 of Fas gene of healthy people in Han nationality in Zhejiang province.DESIGN: Simple random sampling.SETTING: Department of Surgery of the 118 Hospital of Chinese PLA.PARTICIPANTS: A total of 80 healthy people in Han nationality were selected from hospitals in Zhejiang province from August 2005 to January 2006. There were 43 males and 37 females aged from 3 to 78 years with the mean age of 39.5 years, and all subjects were consent. DNA which was used in genetic analysis was selected from peripheral venous blood of all subjects and maintained at -20 ℃.METHODS: Polymorphism sites in exon-4 of p53 gene, promotor of Fas gene and intron-7 of Fas gene were detected with directly DNA sequencing technique.MAIN OUTCOME MEASURES: Polymorphism sites in exon-4 of p53 gene, promotor of Fas gene and intron-7 of Fas gene of healthy people in Han nationality in Zhejiang province.RESULTS: A total of 80 samples were involved in the final analysis. SNPs sites were found at the 119th base of exon-4 of p53 gene (the 72nd codon of p53 gene), the 670th base of upper start codon in promotor of Fas gene (Fas-670), and the 995th base of intron-7 of Fas gene, especially SNPs in the 995th base of intron-7 pf Fas gene, I.e. C→A transversion, was a new site.CONCLUSION: One unknown SNPs site is discovered in intron-7 of Fas gene of people in Han nationality in Zhejiang province. This study also proves that the 72nd codon exists in p53 gene and the -670 polymorphism site exists in promotor of Fas gene.

  9. Association of the KLF14 rs4731702 SNP and Serum Lipid Levels in the Guangxi Mulao and Han Populations

    Directory of Open Access Journals (Sweden)

    Ping Huang

    2013-01-01

    Full Text Available The objective of the present study was to detect the association of the rs4731702 single nucleotide polymorphism (SNP and serum lipid levels in the Guangxi Mulao and Han populations. A total of 727 subjects of Mulao and 740 subjects of Han Chinese were included. Serum low-density lipoprotein cholesterol (LDL-C and apolipoprotein (Apo B levels were higher in Mulao than in Han (P<0.05. The T allele carriers had higher serum LDL-C and ApoAI levels in Mulao, whereas they had lower high-density lipoprotein cholesterol (HDL-C levels and ratio of ApoAI to ApoB in Han (P<0.05 than the T allele noncarriers. Subgroup analyses showed that the T allele carriers had higher HDL-C, LDL-C, and ApoAI levels in Mulao males and lower ApoAI levels and ratio of ApoAI to ApoB in Han males than the T allele noncarriers. The subjects with TT genotype in Han females also had higher total cholesterol, LDL-C, ApoAI, and ApoB levels than the subjects with CT or CC genotype. Serum lipid parameters were also correlated with several environmental factors in both ethnic groups. The differences in the association of KLF14 rs4731702 SNP and serum lipid levels between the two ethnic groups might partly result from different gene-environmental interactions.

  10. 汉墓雕塑群的纪念碑性%The Monumentality of the Han Stone Sculptures of Han' s Tomb

    Institute of Scientific and Technical Information of China (English)

    陈亮

    2012-01-01

    汉代雕塑体现出极强的纪念碑特性,不仅取决于雕塑的尺寸、质地、形状、放置地点和功能,而且也体现在雕塑的形式和风格上。霍去病墓雕塑群是我国雕塑史上的杰作,巨大雄浑的形态、简约朴素的风格和特殊的时代、历史价值使其成为纪念碑性雕塑的代表之作。%Sculptures of the Han Dynasty show a strong memorial style, which can be seen from the size, material, shape, location, function as well as the style. The stone sculptures in front of the tomb of General Huoqubin are masterpieces of Chinese sculptural art. The large scale, simple design and the historical value make them representatives of monumental sculptures of China.

  11. Pharmacokinetics of Lidocaine Hydrochloride Metabolized by CYP3A4 in Chinese Han Volunteers Living at Low Altitude and in Native Han and Tibetan Chinese Volunteers Living at High Altitude.

    Science.gov (United States)

    Zhang, Juanling; Zhu, Junbo; Yao, Xingchen; Duan, Yabin; Zhou, Xuejiao; Yang, Meng; Li, Xiangyang

    2016-01-01

    To investigate the pharmacokinetics of lidocaine hydrochloride metabolized by cytochrome P450 3A4 (CYP3A4) in Chinese Han volunteers living at low altitude (LA) and in native Han and Tibetan Chinese volunteers living at high altitude, lidocaine hydrochloride 10 mg was given by intramuscular injection to 3 groups: Han volunteers living at LA, and native Han and Tibetan volunteers living at a high altitude. Blood samples were collected before the (baseline) study drug was given and at 0.25, 0.5, 1.0, 1.5, 2.0, 3.0, 4.0, 6.0, 8.0 h after study drug administration. Lidocaine hydrochloride in plasma was determined by RP-HPLC. Pharmacokinetics parameters of lidocaine hydrochloride showed that there were no significant difference between the native Han and Tibetan volunteers, but the t1/2 was 29.8 and 29.8% higher in 2 groups, respectively, than in the LA group. To study related mechanism, the effects of exposure to chronic high-altitude hypoxia (CHH) on the activity and expression of CYP3A1 were examined in rats. Rats were divided into LA, chronic moderate altitude hypoxia, and CHH groups. CHH caused significant decreases in the activity and protein and mRNA expression of rat CYP3A1 in vivo. This study found significant changes in the disposition of lidocaine hydrochloride in native healthy Tibetan and Han Chinese subjects living at a high altitude in comparison to healthy Han Chinese subjects living at LA, it might be due to significant decreases in the activity and protein and mRNA expression of CYP3A4 under CHH condition. PMID:26730802

  12. Association of TLR9 polymorphisms with sporadic Parkinson's disease in Chinese Han population.

    Science.gov (United States)

    Zhu, Konghua; Teng, Jijun; Zhao, Jing; Liu, Hongxin; Xie, Anmu

    2016-07-01

    Previous studies have acknowledged that inflammatory reaction has implicated in Parkinson's disease (PD) pathogenesis nowadays. Toll-like receptors (TLRs), as key players in the inflammatory reaction, play a pivotal role in the PD pathogenesis and accumulating evidences have shown that TLRs are increased in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of PD. Therefore, the present study aimed to identify the role of the polymorphisms of rs187084 and rs352140 in TLR9 gene with PD. The genotypes were detected by polymerase chain reaction and restriction fragment length polymorphism analysis in 380 PD patients and 380 healthy matched individuals in Chinese Han population. For rs352140, our data revealed a significant difference in allele distribution in female PD group and its healthy matched control (P = 0.040). Moreover, rs352140 T allele carriers of female group were associated with a reduced risk of PD (TT + TC vs. CC, P = 0.018). However, no significant differences in genotype and allele distribution were found between the age and gender subgroups for rs187084. Therefore, our studies indicate that the rs352140 gene polymorphism may be associated with the susceptibility of female PD in Chinese Han population. PMID:26000920

  13. Polymorphism Profile of Nine Short Tandem Repeat Loci in the Han Chinese

    Institute of Scientific and Technical Information of China (English)

    Shuangding Li; Chunxia Yan; Yajun Deng; Ruilin Wang; Jian Wang; Huanming Yang; Shengbin Li

    2003-01-01

    Nine short tandem repeat (STR) markers (D3S1358, VWA, FGA, THO1, TPOX,CSFIPO, D5S818, D13S317, and D7S820) and a sex-identification marker (Amel-ogenin locus) were amplified with multiplex PCR and were genotyped with afour-color fluorescence method in samples from 174 unrelated Han individuals inNorth China. The allele frequencies, genotype frequencies, heterozygosity, prob-ability of discrimination powers, probability of paternity exclusion and Hardy-Weinberg equilibrium expectations were determined. The results demonstratedthat the genotypes at all these STR loci in Han population conform to Hardy-Weinberg equilibrium expectations. The combined discrimination power (DP) was1.05 × 10-10 within nine STR loci analyzed and the probability of paternity exclusion(EPP) was 0.9998. The results indicate that these nine STR loci and the Amelo-genin locus are useful markers for human identification, paternity and maternitytesting and sex determination in forensic sciences.

  14. Autonomous dynamics in neural networks: the dHAN concept and associative thought processes

    Science.gov (United States)

    Gros, Claudius

    2007-02-01

    The neural activity of the human brain is dominated by self-sustained activities. External sensory stimuli influence this autonomous activity but they do not drive the brain directly. Most standard artificial neural network models are however input driven and do not show spontaneous activities. It constitutes a challenge to develop organizational principles for controlled, self-sustained activity in artificial neural networks. Here we propose and examine the dHAN concept for autonomous associative thought processes in dense and homogeneous associative networks. An associative thought-process is characterized, within this approach, by a time-series of transient attractors. Each transient state corresponds to a stored information, a memory. The subsequent transient states are characterized by large associative overlaps, which are identical to acquired patterns. Memory states, the acquired patterns, have such a dual functionality. In this approach the self-sustained neural activity has a central functional role. The network acquires a discrimination capability, as external stimuli need to compete with the autonomous activity. Noise in the input is readily filtered-out. Hebbian learning of external patterns occurs coinstantaneous with the ongoing associative thought process. The autonomous dynamics needs a long-term working-point optimization which acquires within the dHAN concept a dual functionality: It stabilizes the time development of the associative thought process and limits runaway synaptic growth, which generically occurs otherwise in neural networks with self-induced activities and Hebbian-type learning rules.

  15. Drought analysis using multi-scale standardized precipitation index in the Han River Basin, China

    Institute of Scientific and Technical Information of China (English)

    Yue-ping XU; Sheng-ji LIN; Yan HUANG; Qin-qing ZHANG; Qi-hua RAN

    2011-01-01

    Regional drought analysis provides useful information for sustainable water resources management. In this paper, a standardized precipitation index (SPI) at multiple time scales was used to investigate the spatial patterns and trends of drought in the Han River Basin, one of the largest tributaries of Yangtze River, China. It was found that, in terms of drought severity, the upper basin of the Hart River is the least, while the growing trend is the most conspicuous; a less conspicuous growing trend can be observed in the middle basin; and there is an insignificant decreasing trend in the lower basin. Meanwhile, the impact of drought on the Middle Route of the South-to-North Water Transfer Project was investigated, and it is suggested that water intake must be reduced in times of drought, particularly when successive or simultaneous droughts in the upper and middle basins of the Han River Basin occur. The results can provide substantial information for future water allocation schemes of the South-to-North Water Transfer Project.

  16. Pollution from animal husbandry in China: a case study of the Han River Basin.

    Science.gov (United States)

    Sun, Chen; Wu, Hongjuan

    2012-01-01

    Animal husbandry is one of the major agricultural pollution sources in China. The Xiangyang Reach of the Han River Basin was used as a case study to identify pollutants from animal rearing. The gross amount of pollutants from livestock and poultry rearing in the Xiangyang Reach was estimated using two empirical models with different data sets. The pig, cattle, sheep, and poultry population in 2009 amounted to 2.6, 0.6, 0.5, and 39.2 million head, respectively. The total annual pollutant loads generated from the feces and urine of livestock and poultry were 270,400 t of chemical oxygen demand; 228,900 t of biochemical oxygen demand; 26,500 t of ammonia nitrogen; 16,500 t of total phosphorus; and 63,900 t of total nitrogen. Approximately 12% of these pollutant loads were estimated to enter the Han River through the watershed outlet. Animal breeding has been one of the main pollution sources in this area, followed by domestic sewage and industrial wastewater. Cattle produced the most pollution, with the heaviest pollution load in downtown Xiangyang City. Several recommendations are presented to control the pollution caused by livestock and poultry breeding. PMID:22766880

  17. The Life and Works of Han Shin Gwang : a Midwife and Nurse of Korean Modern Times

    Directory of Open Access Journals (Sweden)

    YI Ggodme

    2006-06-01

    Full Text Available Han Shin Gwang, born in an early Christian family in Korea in 1902, could get western education different from the ordinary Korean girls in that period. She participated in the 1919 Samil Independence Movement in her teens, and got nursing and midwifery education in a missionary hospital. She got a midwife license and worked as a member in an early mother-and-child health center. She organized 'Korean Nurses' Association' in 1924 and focused on public health movement as the chairwoman. She actively participated in women's movement organizations, and Gwangjoo Student's Movement. She was known to be a representative of leading working women, and wrote articles on woman's right, the needs and works of nurses and midwives. From late Japanese colonial period, she opened her own clinic and devoted herself to midwifery. After the Korean Liberation in 1945, she began political movement and went in for a senate election. During the Korean War, she founded a shelter for mothers and children in help. After the War, she reopened a midwifery clinic and devoted to the works of Korean Midwives' Association. Han Shin Gwang's life and works belong to the first generation of Korean working women in modern times. She actively participated in women's movement, nurses' and midwives professional movement, Korea liberation movement, and mother-and-child health movement for 60 years. Her life is truly exemplary as one of the first generation of working women in modern Korea, distinguished of devotion and calling.

  18. Association of polymorphisms in the DCDC2 gene with developmental dyslexia in the Han Chinese

    Institute of Scientific and Technical Information of China (English)

    ZUO Peng-xiang; WU Han-rong; LI Zeng-chun; CAO Xu-dong; PANG Li-juan; YANG Lan; LIU Fan; ZHAO Feng

    2012-01-01

    Background Genetic association studies on populations of European origin have identified the DCDC2 gene as a susceptibility locus for developmental dyslexia.Here,we sought to investigate the association of DCDC2 polymorphisms with developmental dyslexia in children of Han Chinese origin.Methods We undertook a case-control genetic association study on 76 dyslexic children and 79 non-dyslexic matched controls.We isolated DNA from oral mucosal cell samples and genotyped two DCDC2 coding-sequence single nucleotide polymorphisms,rs2274305 and rs6456593,in each sample using SNaPshot single nucleotide extension.We compared the allele and genotype frequencies between the groups using the X2 test and analyzed the relationship between dyslexia and the polymorphism at both loci using unconditional logistic regression.We also predicted haplotypes and compared their frequencies between the two groups.Results The differences in the genotype distribution and the allelic genes of the two single nucleotide luci of the DCDC2 gene,rs2274305 and rs6456593,between the two dyslexic and non-dyslexic groups were statistically meaningless (P >0.05).The differences in the haplotype distributions of the DCDC2 gene between the dyslexic and normal group were statistically meaningless (P >0.05).Conclusion The DCDC2 gene may not be a susceptibility factor for developmental dyslexia among the Han Chinese.However,methodological issues may have prevented the detection of oositive associations.

  19. PIXE study on ancient glass samples of the Han dynasty unearthed from Hepu county, Guangxi

    International Nuclear Information System (INIS)

    Combining the modified external-beam proton induced X-ray emission (PIXE), inductively coupled plasma atomic emission spectrometry (ICP-AES) and other techniques, the chemical compositions, structures and other properties of some ancient glass samples of the Han Dynasty, which were unearthed from Hepu county, Guangxi, were determined. These glass samples can be classified to several glass systems, such as K2O-SiO2, PbO-BaO-SiO2, PbO-SiO2, Na2O-K2O-PbO-SiO2 and (Na2O)K2O-CaO-SiO2. But most of the samples belong to K2O-SiO2 system glass. Due to the surface corrosion, the flux K2O in the surface of the K2O-SiO2 glass was lost, but with the relative enrichment of the SiO2. Based on the characteristics of chemical composition and appearance of these samples, it is thought that, during the Han Dynasty, the making technique of the K2O-SiO2 glass in China was influenced by the technique related to the PbO-BaO-SiO2 glass from abroad. (authors)

  20. Polymorphism of the catechol-O-methyltransferase gene in Han Chinese patients with psoriasis vulgaris

    Directory of Open Access Journals (Sweden)

    Lin Gao

    2009-01-01

    Full Text Available Psoriasis vulgaris is defined by a series of linked cellular changes in the skin: hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils and other types of leukocytes in the affected skin. Catechol-O-methyltransferase ( COMT 158 polymorphism can reduce the activity of the COMT enzyme that may trigger defective differentiation of keratinocytes in psoriasis. Immunocytes can degrade and inactivate catecholamines via monamine oxidase (MAO and COMT in the cells. We hypothesized that the COMT-158 G > A polymorphism was associated with the risk of psoriasis vulgaris in Han Chinese people. In a hospital-based case-control study, 524 patients with psoriasis vulgaris and 549 psoriasis-free controls were studied. COMT-158 G > A polymorphism was genotyped using the PCR sequence-specific primer (PCR-SSP technique. We found no statistically significant association between the COMT-158 allele A and the risk of psoriasis vulgaris (p = 0.739 adjusted OR = 1.03; 95% CI = 0.81-1.31. This suggests that the COMT-158 G > A polymorphism may not contribute to the etiology of psoriasis vulgaris in the Han Chinese population.

  1. TPM1 polymorphisms and nonsyndromic orofacial clefts susceptibility in a Chinese Han population.

    Science.gov (United States)

    Qian, Yajing; Li, Dandan; Ma, Lan; Zhang, Hongchuang; Gong, Miao; Li, Sheng; Yuan, Hua; Zhang, Weibing; Ma, Junqing; Jiang, Hongbing; Pan, Yongchu; Wang, Lin

    2016-05-01

    Located at 15q22 a susceptibility region for nonsyndromic orofacial clefts (NSOC), TPM1 encodes a group of highly conserved ubiquitous actin-binding proteins involved in the muscle contraction and cytoskeleton organization. Considering the multiple functions of TPM1 gene, we investigated the potential relationship between TPM1 polymorphisms and risk of NSOC in a Chinese Han population. Four tag single nucleotide polymorphisms (tSNPs) of TPM1 (rs11071720, rs3803499, rs12148828, and rs1972041) were selected to conduct a case-control study with 673 NSOC patients and 705 unrelated healthy controls from a Chinese Han population. The SNPs were genotyped by the IPLEX Sequenom MassARRAY platform. SNP rs1972041GA showed a decreased risk of NSOC in heterozygotes (P = 0.038, OR = 0.77, 95%CI = [0.61, 0.99]). Further stratified analysis revealed an enhanced protective effect of the minor allele G at rs197204 on lip with cleft palate (CLP) and cleft lip with or without cleft palate (CL/P) groups under a codominant or dominant model. No association was observed between the remaining three markers (rs11071720, rs3803499, and rs12148828) and NSOC as well as its subgroups. TPM1 polymorphisms might contribute to the etiology of NSOC, and more emphasis should be placed on TPM1 during craniofacial development. © 2016 Wiley Periodicals, Inc. PMID:26792422

  2. [Genetic variability and phylogenetic analysis of 39 short tandem repeat loci in Beijing Han population].

    Science.gov (United States)

    Xiuyan, Ruan; Weini, Wang; Yaran, Yang; Bingbing, Xie; Jing, Chen; Yacheng, Liu; Jiangwei, Yan

    2015-07-01

    In this study, we studied the genetic polymorphisms of short tandem repeat (STR) loci from 13 CODIS and 26 non-CODIS system in Beijing Han population for the first time, and established a database of 39 STR loci whose forensic parameters were further evaluated. Our results demonstrated no significant deviation from the Hardy-Weinberg equilibrium of 39 STR loci and no pairwise linkage disequilibrium between them. The power of discriminations, expected heterozygosity, polymorphic information content, and power of exclusion of 39 STR loci ranged from 0.7740-0.9818, 0.6000-0.9350, 0.5317-0.9047 and 0.2909-0.8673. The cumulated discrimination power and cumulative probability of exclusion were 0.999999999999999999999999999999999999999964971 and 0.999999999973878, respectively. Moreover, the genetic distance was calculated based on allele frequency and phylogenetic tree was built using STR loci data from Beijing Han and other 11 Chinese ethnic groups.This study provides important basic data for Chinese forensic DNA database and population genetics database, and has important significance in carrying out forensic individual identification, paternity testing, and population genetic study. PMID:26351168

  3. A case-control association study of NRXN1 polymorphisms with schizophrenia in Chinese Han population

    Directory of Open Access Journals (Sweden)

    Lu Tianlan

    2011-04-01

    Full Text Available Abstract Background Recent research has implicated that mutations in the neurexin-1 (NRXN1 gene on chromosome 2p16.3 might play a role in schizophrenia, autism, and nicotine dependence. In order to explore the association of NRXN1 polymorphisms with schizophrenia, we made a case-control association study in Chinese Han population. Methods We examined six tag single nucleotide polymorphisms (SNPs spanning 116.7 kb of NRXN1 in 768 schizophrenic patients and 738 healthy control subjects. The association of NRXN1 polymorphisms with schizophrenia and the age-at-onset of this disease were explored. Results Our results showed that four SNPs of NRXN1 gene were significantly associated with schizophrenia (rs10490168: G > A, p = 0.017; rs2024513: A > G, p = 0.006; rs13382584: T > C, p = 0.009; and rs1558852: G > A, p = 0.031. Furthermore, the association of SNP rs2024513 with schizophrenia remained significance after the Bonferroni correction. Haplotypes consisting of above six SNPs also showed significantly associated with schizophrenia (global chi-square = 14.725, p = 0.022. A protective haplotype AGTGCA remained associated with schizophrenia, even after 10,000 permutation tests (empirical p-value = 0.043. However, we did not find any association with age-at-onset of schizophrenia with NRXN1 polymorphisms. Conclusions Our findings suggest that NRXN1 might represent a major susceptibility gene for schizophrenia in Chinese Han population.

  4. Association of a miRNA-137 Polymorphism with Schizophrenia in a Southern Chinese Han Population

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    Guoda Ma

    2014-01-01

    Full Text Available Both genome wide association study (GWAS and biochemical studies of Caucasian populations indicate a robust association between the miR-137 genetic variant rs1625579 and schizophrenia, but inconsistent results have been reported. To assay the association between this variant and schizophrenia, we genotyped 611 schizophrenic patients from Southern Chinese Han population for the risk single nucleotide polymorphism (SNP rs1625579 using the SNaPshot technique and compared the clinical profiles of different genotypes. Additionally, a meta-analysis was performed using the combined sample groups from five case-control publications and the present study. Both the genotype and allele distributions of the rs1625579 SNP were significantly different between patients and controls (P=0.036 and 0.026, SNP. TT genotype carriers showed slightly lower Brief Assessment of Cognition in Schizophrenia- (BACS- derived working memory performance than G carriers (15.58 ± 9.56 versus 19.71 ± 8.18, P=0.045. In the meta-analysis, we observed a significant association between rs1625579 and schizophrenia under different genetic models (all P<0.05. The results of our study and meta-analysis provide convincing evidence that rs1625579 is significantly associated with schizophrenia. Furthermore, the miR-137 polymorphism influences the working memory performance of schizophrenic patients in a Chinese Han population.

  5. A study of single nucleotide polymorphisms of GRIN2B in schizophrenia from Chinese Han population.

    Science.gov (United States)

    Guo, Zhenming; Niu, Weibo; Bi, Yan; Zhang, Rui; Ren, Decheng; Hu, Jiaxin; Huang, Xiaoye; Wu, Xi; Cao, Yanfei; Yang, Fengping; Wang, Lu; Li, Weidong; Li, Xingwang; Xu, Yifeng; He, Lin; Yu, Tao; He, Guang

    2016-09-01

    Schizophrenia is a severe and complex mental disorder with high heritability. There is evidence that mutations in the gene of Nmethyl-d-aspartate-type glutamate receptors (NMDAR) are associated with schizophrenia. GRIN2B encodes a subunit of NMDARs, and has been identified as a candidate gene for many psychiatric disorders, especially schizophrenia. In this study, we investigated whether single nucleotide polymorphisms (SNPs) in GRIN2B were associated with schizophrenia. Four SNPs (rs890, rs1806191, rs219872, rs172677) were genotyped in 752 schizophrenic patients and 846 healthy controls of the Chinese Han population. Our results indicate differences in allele and genotype frequencies of rs890 between case and control. These results were assessed by adapting different genetic models (codominant, dominant, recessive, overdominant, log-additive models). After controlling for confounding factors including sex and age, rs890 remained associated with schizophrenia. In addition, rs890 and rs1806191 were found to form a haplotype associated with schizophrenia. In summary, our results indicate that the GRIN2B SNP rs890 might be associated with schizophrenia in the Chinese Han population. PMID:27453061

  6. Profiling plasma peptides for the identification of potential ageing biomarkers in Chinese Han adults.

    Directory of Open Access Journals (Sweden)

    Jiapeng Lu

    Full Text Available Advancing age is associated with cardiovascular disease, diabetes mellitus and cancer, and shows significant inter-individual variability. To identify ageing-related biomarkers we performed a proteomic analysis on 1890 Chinese Han individuals, 1136 males and 754 females, aged 18 to 82 years, using weak cation exchange magnetic bead based MALDI-TOF-MS analysis. The study identified 44 peptides which varied in concentration in different age groups. In particular, apolipoprotein A-I (ApoA1 concentration gradually increased between 18 to 50 years of age, the levels of fibrinogen alpha (FGA decreased over the same age span, while albumin (ALB was significantly degraded in middle-aged individuals. In addition, the plasma peptide profiles of FGA and four other unidentified proteins were found to be gender-dependent. Plasma proteins such as FGA, ALB and ApoA1 are significantly correlated with age in the Chinese Han population and could be employed as indicative ageing-related biomarkers.

  7. The association analysis polymorphism of CDKAL1 and diabetic retinopathy in Chinese Han population

    Science.gov (United States)

    Liu, Nai-Jia; Xiong, Qian; Wu, Hui-Hui; Li, Yan-Liang; Yang, Zhen; Tao, Xiao-Ming; Du, Yan-Ping; Lu, Bin; Hu, Ren-Ming; Wang, Xuan-Chun; Wen, Jie

    2016-01-01

    AIM To identify the contribution of CDKAL1 to the development of diabetic retinopathy (DR) in Chinese population. METHODS A case-control study was performed to investigate the genetic association between DR and polymorphic variants of CDKAL1 in Chinese Han population with type 2 diabetes mellitus (T2DM). A well-defined population with T2DM, consisting of 475 controls and 105 DR patients, was recruited. All subjects were genotyped for the genetic variant (rs10946398) of CDKAL1. Genotyping was performed by iPLEX technology. The association between rs10946398 and T2DM was assessed by univariate and multivariate logistic regression (MLR) analysis. RESULTS There were significant differences in C allele frequencies of rs10946398 (CDKAL1) between control and DR groups (45.06% versus 55.00%, P<0.05). The rs10946398 of CDKAL1 was found to be associated with the increased risk of DR among patients with diabetes. CONCLUSION Our findings suggest that rs10946398 of CDKAL1 is independently associated with DR in a Chinese Han population.

  8. Vitamin D receptor genetic polymorphisms and tuberculosis among Chinese Han ethnic group

    Institute of Scientific and Technical Information of China (English)

    CAO Shang; LUO Peng-fei; LI Wei; TANG Wan-qin; CONG Xiao-na; WEI Ping-min

    2012-01-01

    Background In epidemiological studies,tuberculosis (TB) appears intimately with vitamin D insufficiency whereas its relationship with vitamin D receptor (VDR) polymorphism caused by radical difference remains unspecified.This study aimed to investigate the relationship between vitamin D genetic polymorphism and tuberculosis in Han ethnic group.Methods Meta-analysis was adopted in the synthetic quantitative analysis of documents home and abroad on the relationship between vitamin D genetic polymorphisms and tuberculosis,which were openly published during June 2000 to January 2010.Random effect model and fixed effect model analyses were used to calculate the incorporated odds ratio (OR) based on the heterogeneity test data.Results A total of 6 eligible studies were included in this analysis.The Fokl-ff genotype showed a significant marginal association (Fixed effect model:OR 1.91,95% CI 1.44-2.52; Random effect model:OR 1.91,95% CI 0.94-3.88),yet Taql polymorphisms was not significantly related to TB.Conclusion The interaction between FoKI genotype polymorphism and TB observed demonstrates that vitamin D deficiency might exist as a risk factor during the development of TB in Han ethnic group and more evidences needed to validate the conclusion.

  9. Medicinal use of earths and minerals from Hippocrates to Sir Hans Sloane and beyond.

    Science.gov (United States)

    Retsas, Spyros

    2012-12-01

    In 1931 two pharmaceutical drawers containing mineral specimens, belonging to Sir Hans Sloane, the 18th century collector, Royal Physician, President of the Royal Society and of the Royal College of Physicians of London, were found in the Department of Botany of the Natural History Museum (NHM) of London. The drawers, each divided into 49 compartments, contained a total of 107 mineral pharmaceutical specimens, some labelled as mercury or white arsenic. Their registration, identification with the Sloane Manuscript Catalogues and subsequent transfer to the Mineralogy department of the NHM where one of these drawers is now on public display, had been documented by 1935. In antiquity therapeutic empiricism attributed medicinal properties to animal products, plants and minerals, including the soil of specific geographic locations. This communication traces the medicinal use of certain earths and minerals, listed in Sir Hans Sloane's manuscript catalogues, to classical antiquity with a reference to Arsenic compounds, which in our time are finding application in the treatment of acute promyelocytic leukaemia and to Terra Lemnia, a celebrated antidote of repute spanning twenty centuries, also included in the Sloane collections. PMID:26255390

  10. Association study of monoamine oxidase A/B genes and schizophrenia in Han Chinese

    Directory of Open Access Journals (Sweden)

    Li Sheng-Bin

    2011-10-01

    Full Text Available Abstract Background Monoamine oxidases (MAOs catalyze the metabolism of dopaminergic neurotransmitters. Polymorphisms of isoforms MAOA and MAOB have been implicated in the etiology of mental disorders such as schizophrenia. Association studies detected these polymorphisms in several populations, however the data have not been conclusive to date. Here, we investigated the association of MAOA and MAOB polymorphisms with schizophrenia in a Han Chinese population. Methods Two functional single nucleotide polymorphisms (SNPs, rs6323 of MAOA and rs1799836 of MAOB, were selected for association analysis in 537 unrelated schizophrenia patients and 536 healthy controls. Single-locus and Haplotype associations were calculated. Results No differences were found in the allelic distribution of rs6323. The G allele of rs1799836 was identified as a risk factor in the development of schizophrenia (P = 0.00001. The risk haplotype rs6323T-rs1799836G was associated with schizophrenia in female patients (P = 0.0002, but the frequency difference was not significant among male groups. Conclusions Our results suggest that MAOB is a susceptibility gene for schizophrenia. In contrast, no significant associations were observed for the MAOA functional polymorphism with schizophrenia in Han Chinese. These data support further investigation of the role of MAO genes in schizophrenia.

  11. Histopathological Analysis of Liver During Pregnancy Toxemia in Small-tailed Han Sheep

    Institute of Scientific and Technical Information of China (English)

    Mingcheng WANG; Enzhong LI; Gailing WANG

    2014-01-01

    The present work aimed to investigate the microscopic and ultramicro-scopic structure of the liver to assess the level of hepatic impairment during preg-nancy toxemia. Seven pregnant smal-tailed Han sheep of negative urine ketone bodies were assessed in this study. Toxemia was induced by limiting food and movement late in pregnancy. Three sheep developed obvious clinical symptoms with motor weakness, depression, anorexia, locomotion disturbances, blindness and lan-guishment. We harvested their liver tissues as pathological material, and used rou-tine histological and electronic microscopy methods to observe the histopathological changes in smal-tailed Han sheep induced by pregnancy toxemia. Autopsy of the livers of the sheep revealed deep yel ow coloration, intumescence and hemorrhage on the surface. Microstructural features indicated fatty degeneration, which is a main characteristic of fatty liver. Hepatocel ular ultrastructural changes were observed un-der an electronic microscope. The characteristic findings were nucleolus concentra-tion, vacuolation of mitochondria and excessive glycogen granules in the cytoplasm. Via this experimental protocol, pregnancy toxemia of sheep was successful y in-duced, providing a pathological model for the study of this disease. After the experi-mental induction of pregnancy toxemia, the clinical symptoms of pathogenic sheep and pathological changes to their livers exhibited obvious characteristics of pregnan-cy toxemia.

  12. Metástasis pulmonar miliar como primera manifestación de carcinoma de tiroides bien diferenciado en niños

    Directory of Open Access Journals (Sweden)

    Karol Federico

    2005-02-01

    Full Text Available Objetivo: Presentar el caso de una adolescente con manifestaciones de afectación pulmonar como motivo de consulta, debido a una metástasis pulmonar miliar de carcinoma (Ca papilar de tiroides. Caso Clínico: Se trata de una adolescente femenina de 13 años de edad quien presenta tos seca, disnea de esfuerzo, palpitaciones, dolor precordial, y pérdida de peso de 15 días de evolución. Al examen clínico se evidencia aumento de volumen de la región anterior del cuello a predominio izquierdo, con adenopatía cervical palpable, acrocianosis y cianosis peribucal. Hematología completa, función tiroidea y electrocardiograma normales. La gasometría arterial demuestra una hipoxemia severa. En Rx. de tórax se observa infiltrado miliar micro y macronodular bilateral. En ultrasonido impresionan adenopatías de ubicación pretraqueal y paracarotideas. Tomografía de cuello revela imagen altamente sugestiva de malignidad en lóbulo tiroideo izquierdo y tomografía toraco-abdominal muestra infiltrado pulmonar bilateral micronodular sugestivo de lesiones metastásicas. Estudio histopatológico de ganglio latero cervical izquierdo reporta metástasis de Ca papilar tiroideo a predominio de estructuras foliculares. Se hace diagnóstico de carcinoma papilar bien diferenciado de tiroides con metástasis a región pulmonar, se realiza tiroidectomía total y control de T4L y TSH a los 30 y 60 días post cirugía, con valores normales de T4L y ligeramente aumentados de TSH (7 uU/ml, planteándose metástasis pulmonares funcionantes. Se indica terapia ablativa con I131 presentando evolución clínica estable, pero con cifras de 300 mg/dL de tiroglobulina a los seis meses, por lo que se planifica otra sesión con radioyodo. A propósito de este caso, el segundo en cinco años en la Unidad de Endocrinología del IAHULA, se lleva a cabo una revisión de la literatura sobre esta entidad nosológica. Conclusiones: En niños, el Ca papilar de tiroides puede ponerse

  13. Efecto del subprograma de apoyo a los proyectos de inversión rural (PAPIR) en productores que recibieron bienes de capital durante el periodo 2002-2007 en la Región Libres, Puebla, México.

    OpenAIRE

    Soto Reyes, Vianey

    2012-01-01

    El Subprograma de Apoyo a los Proyectos de Inversión Rural (PAPIR), fue un programa diseñado para fomentar la inversión en bienes de capital de la población rural elegible a través del apoyo para la puesta en marcha de proyectos productivos que posibiliten la aplicación de tecnologías apropiadas, la reconversión productiva, el acopio, acondicionamiento y transformación para fortalecer la comercialización de la producción primaria, la generación de empleo rural y de servicios, así como su posi...

  14. Aplicaciones de la tecnología de microondas a la desinsectación en los sectores: Cárnico y de restauración de bienes culturales

    OpenAIRE

    Zona Ortiz, Angela Tatiana

    2008-01-01

    Esta investigación amplia el campo de aplicación para el calor producido por las microondas en el área de desinsectación dentro de los sectores cárnico y de restauración de bienes culturales. Estableciendo un procedimiento inicial de aplicación que permita la conservación del material a desinsectar (jamón curado y madera), mientras se eliminan los agentes contaminantes (ácaros y carcoma). El objetivo que se persigue es la desinsectación segura, no invasiva y medioambientalmente limpia. La...

  15. Aproximación a la lectura de bienes patrimonializados de la arquitectura racional del s.XX desde la “Dialéctica de la mirada” de Walter Benjamin

    OpenAIRE

    Cuello, Juan Nicolás

    2010-01-01

    En el marco del estudio de las posibles dimensiones epistemológicas del arte, lo que pretendo en este trabajo es abordar una aproximación a las consideraciones que se podrían realizar acerca de la arquitectura moderna o racional, y sobretodo aproximarme a una lectura de esta propuesta estilística desde la metodología desarrollada por Benjamin en su investigación sobre los Pasajes de Paris, conocida como Dialéctica de la mirada. Para ello tomare como ejemplos paradigmáticos dos bienes que son ...

  16. Éduquer au bien-être animal en formation professionnelle : prise en compte de l'empathie interspécifique par le système éducatif

    OpenAIRE

    Vidal, Michel

    2014-01-01

    Les débats scientifico-éthiques relevant du bien-être animal en font une question socialement vive. Nous interrogeons son enseignement en formation agricole, envisagé au travers d'une éducation à l'empathie interspécifique. Nous questionnons les facteurs des éducations formelle, non-formelle et informelle susceptibles de le défavoriser. Notre recherche se fonde sur les discours de 7 élèves en formation relevant de l'élevage d'animaux de production ou d'animaux de compagnie, de 5 enseignants e...

  17. Riesgos en el proceso de importación ordinaria: identificación del mapa de riesgos de la importación de bienes de capital en Colombia

    OpenAIRE

    Gallón Perdomo, Sara María; Torres Muskus, Carlos Henrique

    2014-01-01

    En Colombia, durante el proceso de importación se presentan diversos riesgos, que pueden implicar desde sobrecostos hasta la pérdida de la mercancía -- Considerando que las importaciones son necesarias en las empresas, en la presente investigación se elabora un mapa de riesgos del proceso de importación ordinaria de bienes de capital en el país, con el fin de identificarlos, de tal manera que los importadores estén informados y puedan aplicar los métodos de control pertinentes para la adm...

  18. Salud e Internet o cómo conseguir pacientes crónicos bien informados y autónomos: el caso del EAP Mataró-6 (Barcelona, Cataluña)

    OpenAIRE

    Boté, Clara; Vall Casas, Aurora

    2012-01-01

    La consolidación progresiva del uso de las TIC en la sociedad actual así como el libre acceso a gran cantidad de información sobre salud en Internet, favorecen la aparición de pacientes activos y colaboradores. La relación "profesional sanitario-paciente" está evolucionando hacia un nuevo modelo en el cual se proporciona información adecuada y de calidad para conseguir pacientes expertos, bien informados y autónomos. En Cataluña, el personal de enfermería de atención primaria desarrolla funci...

  19. Ivonne Farah H. / Luciano Vasapollo (Coordinadores), Vivir Bien: ¿Paradigma no capitalista?, Universidad Mayor de San Andrés(CIDES-UMSA) y Departamento de Economía de la Universidad de Roma La Sapienza, 2011, 437 p.

    OpenAIRE

    Perea Sandoval, Carlos

    2013-01-01

    La humanidad se encuentra en una constante búsqueda por construir una ética que permita hacer realidad el re-ligarse con el futuro, lo cual implica generar una convivencia recíproca con la naturaleza y las demás formas de vida, en el camino de la ética del bien común. La construcción de este modelo ético se constituye en una prioridad ya que desde el mismo es posible determinar caminos de acción, que a partir de una postura social y de apoyo mutuo, se concrete en alternativas para enfrentar e...

  20. Tercer Premio del I Concurso de monólogos científicos de la Facultad de Ciencias del Mar y Ambientales. Saber comer para crecer muy bien. La teoría endosimbiótica

    OpenAIRE

    Rodríguez López, Jaime; Cabrera Castro, Remedios; López López, José Antonio; Albendín García, Gemma

    2015-01-01

    La teoría endosimbiótica fue propuesta por Lynn Margulis en 1967 y como tantas otras al principio no fue bien valorada por los científicos. Esta teoría plantea esencialmente que algunos de los orgánulos de las células eucariotas, en particular las mitocondrias y los plastos, fueron en su momento organismos procariontes de vida libre (bacterias), que probablemente tras haber sido fagocitadas no fueron digeridas llegando a formar parte y creando una relación dependiente de la célula que las fag...

  1. La participación como bien de consumo : una aproximación conceptual a las formas de implicación de los usuarios en proyectos audiovisuales colaborativos

    OpenAIRE

    Roig Telo, Antoni

    2010-01-01

    Este artículo centra su atención en el concepto de participación, ampliamente utilizado —y también discutido— para hacer referencia a la implicación de los usuarios en la creación de contenidos audiovisuales en Internet. Particularmente, nos centraremos en la noción de participación de los públicos en el diseño, desarrollo y difusión de productos audiovisuales complejos, como por ejemplo largometrajes, webseries o proyectos ‘crossmedia’. Si bien la mayor parte del debate académico sobre la ca...

  2. Prediction consistency and clinical presentations of breast cancer molecular subtypes for Han Chinese population

    Directory of Open Access Journals (Sweden)

    Huang Chi-Cheng

    2012-09-01

    Full Text Available Abstract Background Breast cancer is a heterogeneous disease in terms of transcriptional aberrations; moreover, microarray gene expression profiles had defined 5 molecular subtypes based on certain intrinsic genes. This study aimed to evaluate the prediction consistency of breast cancer molecular subtypes from 3 distinct intrinsic gene sets (Sørlie 500, Hu 306 and PAM50 as well as clinical presentations of each molecualr subtype in Han Chinese population. Methods In all, 169 breast cancer samples (44 from Taiwan and 125 from China of Han Chinese population were gathered, and the gene expression features corresponding to 3 distinct intrinsic gene sets (Sørlie 500, Hu 306 and PAM50 were retrieved for molecular subtype prediction. Results For Sørlie 500 and Hu 306 intrinsic gene set, mean-centring of genes and distance-weighted discrimination (DWD remarkably reduced the number of unclassified cases. Regarding pairwise agreement, the highest predictive consistency was found between Hu 306 and PAM50. In all, 150 and 126 samples were assigned into identical subtypes by both Hu 306 and PAM50 genes, under mean-centring and DWD. Luminal B tended to show a higher nuclear grade and have more HER2 over-expression status than luminal A did. No basal-like breast tumours were ER positive, and most HER2-enriched breast tumours showed HER2 over-expression, whereas, only two-thirds of ER negativity/HER2 over-expression tumros were predicted as HER2-enriched molecular subtype. For 44 Taiwanese breast cancers with survival data, a better prognosis of luminal A than luminal B subtype in ER-postive breast cancers and a better prognosis of basal-like than HER2-enriched subtype in ER-negative breast cancers was observed. Conclusions We suggest that the intrinsic signature Hu 306 or PAM50 be used for breast cancers in the Han Chinese population during molecular subtyping. For the prognostic value and decision making based on intrinsic subtypes, further prospective

  3. Volume measurement of thalami in normal Chinese Han nationality adults by the high-resolution MRI

    International Nuclear Information System (INIS)

    Objective: To measure the volume of thalamus in 1000 healthy Chinese Han nationality adults, and to analyze the relationship between thalamic volume and age, sex, weight and cerebral volume, to provide reliable data for the construction of database of Chinese adults' digital standard brain. Methods: Totally 1000 healthy Chinese adults of Han nationality aged from 18 to 80 years were recruited.They were divided into 5 groups by age: 18-30, 31-40, 41-50, 51-60 and 61-80 years. Each group included 100 males and 100 females. Brain images were obtained on a 1.5 T MR, and the outline of thalami was drawn with Aquariusws software. Then the thalamic volume was calculated automatically. The volumes of left and right thalamus were compared by paired sample t-test. Thalamic volumes of the same side were compared between males and females by independent sample t-test. And thalamic volumes of different age groups were compared by one-way ANOVA. The relationships between thalamic volume and age, sex, weight and cerebral volume were analyzed respectively. Results: The males' standardized volumes of left and right thalamus of healthy Chinese Han nationality adults were (5776 ± 780), (5655 ± 759) mm3, and they were (5464 ±573), (5360 ± 542) mm3 for female. The males' thalamic volume was more than the females' on the same side (t=2.245, 2.200, P<0.01). The left thalamic volumes of various age groups were (6180 ± 534), (6047 ± 562), (5426 ± 471), (5552 ± 526), (4866 ± 552) mm3, respectively, while the right thalamic volumes of the 5 groups were (6069 ± 532), (5895 ± 539), (5357 ± 480), (5396 ± 445),(4791 ± 558)mm3, respectively. There were statistically significant difference among the 5 groups (F=165.686, 165.235, P<0.01). The left and right thalamic volume were all negatively correlated with age (r=-0.633, -0.645, P<0.05). Conclusions: With high resolution 1.5 T MR scanner,grey matter and white matter can be depicted clearly and the outline of

  4. Modernidad y humanismo civil: debates y perspectivas en torno a la tesis de Hans Baron

    Directory of Open Access Journals (Sweden)

    Sverlij, Mariana

    2013-12-01

    Full Text Available Resumen En 1952, Hans Baron concluye su obra más importante: The Crisis of the early Italian Renaissance, publicada por la Universidad de Princeton en dos volúmenes, en 1955. En ella, Baron desarrolla el concepto de “humanismo civil”, desde el cual analiza el humanismo florentino del siglo XV y, en particular, la obra de Leonardo Bruni. Para Baron, los humanistas florentinos, en su lucha por la libertad de Florencia ante la amenaza de la Milán de los Visconti, articularon una novedosa relación entre intelectualidad y política. Este movimiento intelectual, al mismo tiempo, abrió las puertas al pensamiento moderno. Numerosas críticas recibió, desde entonces, el trabajo de Baron, centralmente, por parte de aquellos que reivindicaron las continuidades entre la Edad Media y el Renacimiento, así como también por parte de los que han leído críticamente el éxito que tuvo la Crisis en las academias norteamericanas y su influencia en la consolidación de la “ideología americana”. El artículo propone una revisión de la tesis de Baron así como de las controversias generadas en torno a ella, para, finalmente, esbozar la posibilidad de revisar el concepto de “humanismo civil” desde la obra de Leon Battista Alberti. Abstract In 1952, Hans Baron finished his most important work, The Crisis of the Early Italian Renaissance, published in two volumes by Princeton University in 1955. In this work, the author expounds on the concept of “civil humanism” which he uses to analyze the Florentine humanism of the fifteenth century, and in particular, Leonardo Bruni’s work. According to Baron, Florentine humanists, fighting for Florence’s freedom against the threat of Visconti’s Milan, developed a novel relationship between intellectualism and politics. This intellectual movement also paved the way for modern thought. Baron’s work has been critically reviewed many times since then, especially, by those who vindicated the

  5. Genetic polymorphism of the 26 short tandem repeat loci in the Chinese Hebei Han population using two commercial forensic kits.

    Science.gov (United States)

    Lei, Liang; Xu, Jie; Du, Qingqing; Fu, Lihong; Zhang, Xiaojing; Yu, Feng; Ma, Chunling; Cong, Bin; Li, Shujin

    2015-01-01

    We determined the allele frequencies and forensic parameters for the 26 short tandem repeat (STR) autosomal markers in two commercial kits (the Investigator HDplex and AmpFLSTR(®) Identifiler(®) systems) for 183 unrelated individuals from the Han population of the Hebei Province of China. The 26 STRs were all in Hardy-Weinberg equilibrium. No linkage disequilibrium was detected between any pair of loci. The combined power of discrimination and the combined power of exclusion for the 26 STR loci were 1-7.74E-31 and 1-1.21E-11, respectively. Six rare alleles of D10S2325 were identified and named 20, 21, 22, 23, 24, and 31. All the length of the six rare alleles were out of the range of allelic ladder. We calculated the population pairwise genetic distance based on the allele frequencies, using published population data including German, central Polish, south Dutch, northeastern Polish, south Brazilian, Korean, Sichuan Han of China, and Shanghai Han of China. Also we examined the population pairwise genetic distance of loci included in Identifiler system between Hebei Han and other ethnic population of China. These 26 autosomal STR loci could provide highly informative polymorphic data for paternity testing and forensic identification in the Hebei Han population in China. Because they are all in linkage equilibrium, they could be used together to solve deficient kinship cases or cases with mutations. PMID:25262358

  6. Population genetics of 17 Y-STR loci in a large Chinese Han population from Zhejiang Province, Eastern China.

    Science.gov (United States)

    Wu, Weiwei; Pan, Lipeng; Hao, Honglei; Zheng, Xiaoting; Lin, Jinfeng; Lu, Dejian

    2011-01-01

    Seventeen Y-STRs (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a, DYS385b, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635 and YGATAH4) were analyzed for 4451 Chinese Han unrelated males from Zhejiang Province, Eastern China, with the AmpFlSTR Yfiler™ PCR Amplification kit. A total of 3389 different haplotypes was identified, of which 2877 were unique and 512 repeatedly found among different individuals. The overall haplotype diversity (HD) and discrimination capacity (DC) were 0.999696 and 0.761402, respectively. Analysis of molecular variance (AMOVA) tests demonstrated that genetic distance between Zhejiang Han and most Chinese Han populations is closer than that between Zhejiang Han and non-Han populations. This study provides information for the application of Y-chromosomal STRs to forensic identification, indicating that the extended genotyping of Y-STRs is needed for forensic practice. PMID:20457064

  7. Ormagöngin hans Nóa. Saga handa börnum

    OpenAIRE

    Ingibjörg Úlfarsdóttir 1972

    2012-01-01

    Ormagöngin hans Nóa er saga handa börnum og öllum þeim sem vilja halda barninu í sér vakandi alla ævi. Nói er forvitinn strákur sem spyr stórra heimspekilegra spurninga og fær svör við þeim eftir ýmsum leiðum. Hann kynnist Ástu Soffíu sem býr á forvitnilegum stað og Ara sem næstum enginn annar sér og vísar honum leið inn í annan tíma.

  8. HANS JONAS: CONSERVACIÓN DE LA NATURALEZA, CONSERVACIÓN DE LA VIDA

    OpenAIRE

    MARIO BURGUI BURGUI

    2015-01-01

    En este artículo se tratan varios problemas relacionados entre sí que el filósofo alemán Hans Jonas estudió. El primero de ellos es la necesidad de una ética específica dedicada a la dimensión moral de los problemas ambientales, desde una perspectiva distinta a la tradicional. El segundo problema ocupa un lugar central en la discusión en ética ambiental: el valor de la naturaleza. ¿Tiene valor intrínseco o sólo un valor instrumental (para satisfacer los intereses del ser humano)? A este respe...

  9. PIXE analysis of western han dynasty ancient glasses unearthed in Yangzhou city

    International Nuclear Information System (INIS)

    Chemical composition analysis is one of the most important research aspects to provide scientific proof for the technical origin and development of Chinese ancient glass. Proton induced X-ray emission (PIXE) technique is a kind of multi-element quantitative analysis method with high sensitivity and without destruction of samples. Chemical composition of the Western Han dynasty glass garment flakes, which were excavated from Yangzhou city, was analyzed by PIXE, quantitatively. It was found that these glass flakes were attributed to PbO-BaO-SiO2 glass originated in China. These flakes all consist of a glass core and a corroded outer layer with different thickness. There are relatively higher PbO, P2O5 and CaO, while much lower BaO and SiO2 in the corroded layers than in the glass cores. The experimental results were discussed

  10. A Moessbauer study of an ancient pottery figure (Western-Han Dynasty)

    International Nuclear Information System (INIS)

    The grey pottery figure manufactured in the Western-Han Dynasty (175-118 B.C.) and the clay gathered from the same site of Beidongshan in Xuzhou have been studied by X-ray Diffration (XRD), X-ray Fluorescence (XRF), and Moessbauer spectroscopy. They were simultaneously fired under the same conditions in different atmospheres at various temperature up to 1100degC. This study deals with the original firing atmosphere, original firing temperature and its provenance. The information mentioned above can be inferred from the method of the refiring pottery and the firing clay. The results of the original firing temperature deduced from both of them are in goodself agreement. It is found that the values of the Moessbauer parameters for the unrefired pottery figure are approximately the same as those for the clay fired at 950degC for five hours in a reduced atmosphere. The XRF analysis confirmed the locality of this pottery figure. (orig.)

  11. Genetic polymorphism of 11 Y-chromosomal STR loci in Yunnan Han Chinese.

    Science.gov (United States)

    Yanmei, Yang; Tao, Gu; Yubao, Zeng; Chunjie, Xiao; Bifeng, Chen; Shi, Luo; Bingying, Xu; Qiang, Jing; Qinyong, Zhuang; Wen, Zhang; Shengjun, Luo; Shengjie, Nie

    2010-02-01

    Allele frequencies and haplotypes of 11 Y-chromosome STR loci, DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 ab, DYS438, DYS439 and DYS437 were determined in 320 unrelated Yunnan Han Chinese males. A total of 293 haplotypes were identified, of which 268 were unique, 23 were shared in two individuals, and 2 were shared in three individuals. The allele diversity values for each locus ranged from 0.4087 (DYS438) to 0.9701 (DYS385). The allele observed haplotypes diversity value was 0.9994. The combined Y-chromosome STR polymorphisms provide a powerful discrimination tool for routine forensic applications. PMID:20129460

  12. Hanning self-convolution window and its application to harmonic analysis

    Institute of Scientific and Technical Information of China (English)

    WEN He; TENG ZhaoSheng; GUO SiYu; WANG JingXun; YANG BuMing; WANG Yi; CHEN Tao

    2009-01-01

    The Hanning self-convotution window (HSCW) is proposed in this paper. And the phase difference correction algorithm based on the discrete spectrum and the HSCW is given. The HSCW has a low peak side lobe level, a high side lobe roll-off rate, and a simple spectrum representation. Hence, leakage errors and harmonic interferences can be considerably reduced by weighting samples with the HSCW, the parameter estimation by the HSCW-based phase difference correction algorithm is free of solving high order equations, and the overall method can be easily implemented in embedded systems. Simu-lation and application results show that the HSCW-based phase difference correction algorithm can suppress the impacts of fundamental frequency fluctuation and white noise on harmonic parameter estimation, and the HSCW is advantageous over existing combined cosine windows in terms of har-monic analysis performance.

  13. FAIRY-TALE REALISM. HANS CHRISTIAN ANDERSEN AND THE MODERN WORLD OF THINGS

    Directory of Open Access Journals (Sweden)

    Frederike Felcht

    2013-01-01

    Full Text Available According to recent research in literary studies, literature has a specific knowledge about things. My contribution supports this thesis by analyzing the world of things in Hans Christian Andersen's fairy tales. Exemplary readings reveal how Andersen's texts acknowledge the power of things in modern life and how these texts thus question scientific and philosophical concepts of subjectivity that dominated in the nineteenth century. The agency of things in Andersen's texts challenges the ideal of a rational subject that acts autonomously. Current theoretical approaches, notably Actor-Network-Theory, allow us to understand the realism of acting things in Andersen's work. That which is marvelous, which is prevalently used to define the genre Fairy Tale in literary studies, is inherent to modernity. The relationship between magic and modernity is different than expected: modernity consists of an interplay between enchantment and disenchantment

  14. FAIRY-TALE REALISM. HANS CHRISTIAN ANDERSEN AND THE MODERN WORLD OF THINGS

    Directory of Open Access Journals (Sweden)

    Frederike Felcht

    2013-01-01

    Full Text Available According to recent research in literary studies, literature has a specific knowledge about things. My contribution supports this thesis by analyzing the world of things in Hans Christian Andersen's fairy tales. Exemplary readings reveal how Andersen's texts acknowledge the power of things in modern life and how these texts thus question scientific and philosophical concepts of subjectivity that dominated in the nineteenth century. The agency of things in Andersen's texts challenges the ideal of a rational subject that acts autonomously. Current theoretical approaches, notably Actor-Network-Theory, allow us to understand the realism of acting things in Andersen's work. That which is marvelous, which is prevalently used to define the genre Fairy Tale in literary studies, is inherent to modernity. The relationship between magic and modernity is different than expected: modernity consists of an interplay between enchantment and disenchantment.

  15. MC1R variants in Chinese Han patients with sporadic Parkinson's disease.

    Science.gov (United States)

    Shi, Chang-He; Wang, Hui; Mao, Cheng-Yuan; Yang, Jing; Song, Bo; Liu, Yu-Tao; Yang, Zhi-Hua; Luo, Hai-Yang; Zhang, Shu-Yu; Wu, Jun; Xu, Yu-Ming

    2016-06-01

    Recently, a variant p.R160W in the MC1R gene was identified that increased the risk of Parkinson's disease (PD) in Spanish population. To explore whether the MC1R gene variants are associated with sporadic PD in Chinese population, we performed a case-control comparison study for comprehensive MC1R variant screening in 510 Chinese Han patients and 495 healthy controls as ethnically matched controls. We identify 5 nonsynonymous variants, including rs34090186 (p.R67Q), rs2228479 (p.V92M), rs33932559 (p.I120T), rs885479 (p.R163Q), and rs372152373 (p.R223W). However, variants mentioned previously did not show association with PD. Our results suggest that variants in MC1R do not play a major role in PD in the Chinese population. PMID:27084066

  16. Suicidal risk factors of recurrent major depression in Han Chinese women.

    Directory of Open Access Journals (Sweden)

    Yuzhang Zhu

    Full Text Available The relationship between suicidality and major depression is complex. Socio- demography, clinical features, comorbidity, clinical symptoms, and stressful life events are important factors influencing suicide in major depression, but these are not well defined. Thus, the aim of the present study was to assess the associations between the above-mentioned factors and suicide ideation, suicide plan, and suicide attempt in 6008 Han Chinese women with recurrent major depression (MD. Patients with any suicidality had significantly more MD symptoms, a significantly greater number of stressful life events, a positive family history of MD, a greater number of episodes, a significant experience of melancholia, and earlier age of onset. Comorbidity with dysthymia, generalized anxiety disorder (GAD, social phobia, and animal phobia was seen in suicidal patients. The present findings indicate that specific factors act to increase the likelihood of suicide in MD. Our results may help improve the clinical assessment of suicide risk in depressed patients, especially for women.

  17. Development of technical design for waste processing and storage facilities for Novi Han repository

    International Nuclear Information System (INIS)

    Empresarion Agrupados Internacional S.A. (Spain) and ENPRO Consult Ltd. (Bulgaria) were awarded a contract by the Central Finance and Contracts Unit to develop the technical design of the waste processing and storage facilities at the Novi Han repository. At present conceptual design phase is finished. This conceptual design covers the definition of the basic design requirements to be applied to the installations defined above, following both European and Bulgarian legislation. In this paper the following items are considered: 1) Basic criteria for the layout and sizing of buildings; 2) Processing of radioactive waste, including: treatment and conditioning of disused sealed sources; treatment of liquid radioactive wastes; treatment of solid radioactive waste; conditioning of liquid and solid radioactive waste; 3) Control of waste packages and 4) Storage of radioactive waste, including storage facility and waste packages. An analysis of inventories of stored and estimated future wastes and its subsequent processes is also presented and the waste streams are illustrated

  18. Evaluación y análisis de la mejora del servicio de autorización de exportación del Registro de Bienes Culturales de Matanzas

    Directory of Open Access Journals (Sweden)

    Justa Bielka Cantillo González

    2011-04-01

    Full Text Available La presente investigación se realiza en el Registro Provincial de Bienes Culturales de Matanzas, donde se implementa un procedimiento creado por el colectivo de la Cátedra de Calidad de la Universidad de Matanzas “Camilo Cienfuegos” para la evaluación y análisis de la mejora del servicio de autorización exportación de bienes culturales.Para desarrollar la investigación se aplicaron las siguientes herramientas: Diagrama de Flujo, Diagrama Causa-Efecto, Encuesta, Análisis Operacional,  Estadística descriptiva, no paramétrica, y multivariada (paquete estadístico SPSS, versión 15.0, Modelos de Frontera (Software EMS, Software Visio, Instrumento Servqual modificado.Los resultados obtenidos en el estudio permitieron comprobar que de los indicadores gestionados por la organización el indicador más afectado es la eficacia y que existen reservas de eficiencia en las que se debe continuar trabajando. Se realiza el análisis causal de los indicadores afectados y se proponen medidas para la mejora de los mismos.

  19. Role of IL-17 Variants in Preeclampsia in Chinese Han Women.

    Directory of Open Access Journals (Sweden)

    Haiyan Wang

    Full Text Available Previous studies have suggested an important role for IL-17, mainly secreted by Th17 cells, in the development of systemic inflammation in preeclampsia (PE. This study therefore investigated the association between genetic variants in IL-17A, IL-17F, and IL-17RA and susceptibility to PE in Chinese Han women. We recruited 1,031 PE patients and 1,298 controls of later pregnant women, and used TaqMan allelic discrimination real-time PCR to genotype the polymorphisms of IL17A rs2275913, IL-17F rs763780, and IL-17RA rs4819554. No significant differences in genotypic or allelic frequencies were found at all three polymorphic sites between PE patients and controls (rs2275913: genotype χ2 = 0.218, p = 0.897 and allele χ2 = 0.157, p = 0.692, OR = 1.024, 95%CI 0.911-1.152; rs763780: genotype χ2 = 1.948, p = 0.377 and allele χ2 = 1.242, p = 0.265, OR = 0.897, 95%CI 0.741-1.086; rs4819554: genotype χ2 = 0.633, p = 0.729 and allele χ2 = 0.115, p = 0.735, OR = 1.020, 95%CI 0.908-1.146. There were also no significant differences in genetic distributions between mild/severe PE or early/late-onset PE and control subgroups. Our data indicate that the genetic variants of rs2275913 in IL-17A, rs763780 in IL-17F, and rs4819554 in IL-17RA may not play a role in the pathogenesis of PE in Chinese Han women. However, these findings should be confirmed in other ethnic populations.

  20. La persona como singularidad concreta en la obra de Hans Urs von Balthasar

    Directory of Open Access Journals (Sweden)

    Anneliese Meis W.

    2001-01-01

    Full Text Available El presente estudio aborda el concepto de persona de Hans Urs von Balthasar en cuanto singularidad concreta, descubierto a través de una intensa lectura analítica de su voluminosa obra, búsqueda a la luz de la pregunta ¿por qué yo soy precisamente yo? En efecto, el teólogo suizo nunca sistematiza su comprensión de persona ­la distingue sí de los conceptos "individuo", "sujeto" y "espíritu­, pese a que se sirve de aquella como de uno de los pilares más significativos de su pensamiento. Los resultados obtenidos evidencian la complejidad de factores conceptuales, que demuestran que el yo tiene su fundamento último en el acto libre del amor infinito, que como tal constituye la persona desde el dinamismo intradivino de las relaciones opuestas entre Padre, Hijo y Espíritu SantoThis paper regards the concept of person as a concrete singularity in Hans Urs Von Balthasar's work. Such concept rose after a deep analytical reading of his voluminous work, in the light of the guiding question; Why am I, precisely I? The Swiss theologian distinguishes person from the concepts "individual", "subject" and "spirit", but he never synthesises his understanding of person, even though he uses it as one of the most significant pillars of his thought. The results obtained from the research confirm the complexity of the conceptual factors, which show that one's self has its deepest foundation in the free act of the infinite love, which as such, constitutes the person from the intra-divine dynamism of the opposed relations between the Father, Son and Holy Spirit

  1. Common variants in QPCT gene confer risk of schizophrenia in the Han Chinese population.

    Science.gov (United States)

    Khan, Raja Amjad Waheed; Chen, Jianhua; Shen, Jiawei; Li, Zhiqiang; Wang, Meng; Wen, Zujia; Song, Zhijian; Li, Wenjin; Xu, Yifeng; Shi, Yongyong; Yi, Qizhong; Ji, Weidong

    2016-03-01

    Schizophrenia (SCZ) is a common and severe mental disorder, its etiology has not been elucidated completely. In one previous genome-wide association study (GWAS) of SCZ in the Caucasian population, the QPCT has been reported as susceptible gene for SCZ. The QPCT gene encodes Glutaminyl cyclase (QC), an enzyme which is involved in the post translational modification by converting N-terminal glutamate of protein to pyroglutamate, which is resistant to protease degradation, more hydrophobic, and prone to aggregation and neurotoxic. To further investigate the role of this gene in the pathogenesis of schizophrenia in the Han Chinese population, we conducted this study in 1,248 (Mean age ± S.D, 36.44 years ± 9.0) SCZ cases, 1,248 (Mean age ± S.D, 30.62 years ± 11.35) healthy control samples for a case control study. We genotyped six SNPs in this study, including one positive SNP of the previous study, using the Sequenom MassARRAY platform. We found that rs2373000 was significantly associated with SCZ before correction [rs2373000: P allele = 0.016, χ(2)  = 5.784, OR [95%CI] = 0.861 [0.762-0.972], P genotype = 0.018, χ(2)  = 0.069]. After permutation correction for multiple testing, rs2373000 [rs2373000: P Allele corrected = 0.063, P genotype corrected = 0.069] showed marginal association with SCZ. Additionally, one pathogenic haplotype (TGT) containing rs2373000 was also significantly associated with SCZ. Our results are consistent with the findings of previous study and the genetic risk of QPCT gene for SCZ also exists in the Han Chinese population. © 2015 Wiley Periodicals, Inc. PMID:26492838

  2. Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population

    Science.gov (United States)

    Wang, Xiaoliang; Tang, Huamei; Teng, Mujian; Li, Zhiqiang; Li, Jianguo; Fan, Junwei; Zhong, Lin; Sun, Xing; Xu, Junming; Chen, Guoqing; Chen, Dawei; Wang, Zhaowen; Xing, Tonghai; Zhang, Jinyan; Huang, Li; Wang, Shuyun; Peng, Xiao; Qin, Shengying; Shi, Yongyong; Peng, Zhihai

    2014-01-01

    Background Elucidating the genetic basis underlying hepatic gene expression variability is of importance to understand the aetiology of the disease and variation in drug metabolism. To date, no genome-wide expression quantitative trait loci (eQTLs) analysis has been conducted in the Han Chinese population, the largest ethnic group in the world. Methods We performed a genome-wide eQTL mapping in a set of Han Chinese liver tissue samples (n=64). The data were then compared with published eQTL data from a Caucasian population. We then performed correlations between these eQTLs with important pharmacogenes, and genome-wide association study (GWAS) identified single nucleotide polymorphisms (SNPs), in particular those identified in the Asian population. Results Our analyses identified 1669 significant eQTLs (false discovery rate (FDR) < 0.05). We found that 41% of Asian eQTLs were also eQTLs in Caucasians at the genome-wide significance level (p=10−8). Both cis- and trans-eQTLs in the Asian population were also more likely to be eQTLs in Caucasians (p<10−4). Enrichment analyses revealed that trait-associated GWAS-SNPs were enriched within the eQTLs identified in our data, so were the GWAS-SNPs specifically identified in Asian populations in a separate analysis (p<0.001 for both). We also found that hepatic expression of very important pharmacogenetic (VIP) genes (n=44) and a manually curated list of major genes involved in pharmacokinetics (n=341) were both more likely to be controlled by eQTLs (p<0.002 for both). Conclusions Our study provided, for the first time, a comprehensive hepatic eQTL analysis in a non-European population, further generating valuable data for characterising the genetic basis of human diseases and pharmacogenetic traits. PMID:24665059

  3. Enhanced Diabetes Susceptibility in Community Dwelling Han Elders Carrying the Apolipoprotein E 3/3 Genotype.

    Science.gov (United States)

    Ban, Chun-Xia; Zhong, Li; Wang, Tao; Zhu, Min-Jie; Wang, Jing-Hua; Zhang, Zhen-Lian; Wang, Zhe; Su, Ning; Liu, Yuan-Yuan; Shi, Yan-Chen; Xiao, Shi-Fu; Li, Xia

    2016-01-01

    Despite Apolipoprotein E (ApoE) being one of the main apolipoproteins in the blood, the association between its genotype and the high cholesterol or blood glucose levels commonly seen in clinical practice is inconclusive. Such research is also lacking in the Han population. The aim of this study was to investigate the association between APOE genotype, diabetes, and plasma glucose and lipid levels. We included 243 community-dwelling elderly residents in this study. Participant APOE genotypes were assessed and were simultaneously tested for weight, height, blood glucose, triglycerides, cholesterol, and high- and low-density lipoprotein. In addition, gender, age, years of education, cognitive function, and medical history was recorded. Subjects were divided into 3 groups based on APOE genotype: APOE ε2 group (ε2/ε2 and ε2/ε3), APOE ε3 group (ε3/ε3), and APOE ε4 group (ε2/ε4, ε3/ε4 and ε4/ε4). Comparisons between groups were conducted for the incidence of diabetes, high blood pressure, and dementia, as well as for differences in body-mass index, fasting plasma glucose, and blood lipids. The APOE ε3/ε3 genotype exhibited the highest frequency (70.4%) among the subjects. Participants in the APOE ε3 group demonstrated significantly higher levels of fasting plasma glucose than those in the APOE ε2 and APOE ε4 groups (Pfasting plasma glucose values than did the APOE ε2 group (P = 0.065). Furthermore, the APOE3 genotype was significantly correlated with both fasting plasma glucose level and glucose abnormality (P< 0.05) and trended toward statistically significant correlation with diabetes (P = 0.082). The correlation between APOE2 and low low-density lipoprotein levels also approached statistical significance (P = 0.052). Thus, elderly community dwelling residents of Han ethnicity carrying the APOE ε3/ε3 genotype might have higher plasma glucose levels and a higher occurrence of diabetes. PMID:26998902

  4. KALRN Rare and Common Variants and Susceptibility to Ischemic Stroke in Chinese Han Population.

    Science.gov (United States)

    Dang, Meizheng; Wang, Zhenzhen; Zhang, Ruyou; Li, Xiaoying; Peng, Yanqing; Han, Xuesong; Sun, Litao; Tian, Jiawei

    2015-09-01

    Stroke is the second most common cause of mortality worldwide, and it is a major cause of physical disability. Several genome-wide association studies have yielded numerous common variants which increase the risk of ischemic stroke, including the Kalirin-coding gene, KALRN. KALRN strongly associates with early-onset coronary artery disease and atherosclerosis and plays an important role in stroke in the European population. In this study, we analyzed four KALRN gene SNPs in 503 ischemic stroke patients and 493 control subjects, separating the patients into separate research groups based on comorbidity with hypertension or diabetes and stroke type (atherosis or lacunar and combination type). We found a rare variant of KALRN, rs11712619, that associated with lacunar stroke in the northern Chinese Han population with an average-risk allele frequency 0.009 (OR 2.95, 95 % CI 1.08-8.01, p = 0.028). However, after adjusting for relevant factors, including sex, age, body mass index, dyslipidemia, alcohol consumption, and smoking, this association was not evident. Additionally, the KALRN variant rs6438833 was associated with ischemic stroke, ischemic stroke comorbid with diabetes, and lacunar stroke after adjusting for the relevant factors (p = 0.046, p = 0.019 and p = 0.046, respectively), which remained significant after 10,000 permutation procedure test (p' = 0.047, p' = 0.018 and p' = 0.048, respectively). The association of these rare and common variants of KALRN with ischemic stroke in northern Chinese Han population offers insight for potential therapeutic research. PMID:25917671

  5. Association of COL4A1 gene polymorphisms with cerebral palsy in a Chinese Han population.

    Science.gov (United States)

    Bi, D; Wang, H; Shang, Q; Xu, Y; Wang, F; Chen, M; Ma, C; Sun, Y; Zhao, X; Gao, C; Wang, L; Zhu, C; Xing, Q

    2016-08-01

    The basement membrane (BM) is an extracellular matrix associated with overlying cells and is important for proper tissue development, stability, and physiology. COL4A1 is the most abundant component of type IV collagen in the BM, and COL4A1 variants can present with variable phenotypes that might be related to cerebral palsy (CP). We postulated, therefore, that variations in the COL4A1 gene might play an important role in the etiology of CP. In this study, six single nucleotide polymorphisms (SNPs) in the COL4A1 gene were genotyped among 351 CP patients and 220 healthy controls from the Chinese Han population. Significant association was found for an association between CP and rs1961495 (allele: p = 0.008, odds ratio (OR) = 1.387, 95% confidence interval (CI) = 1.088-1.767) and rs1411040 (allele: p = 0.009, OR = 1.746, 95% CI = 1.148-2.656) SNPs of the COL4A1 gene. Multifactor dimensionality reduction analysis suggested that these SNPs had interactive effects on the risk of CP. This study is the first attempt to investigate the contribution of polymorphisms in the COL4A1 gene to the susceptibility of CP in a Chinese Han population. This study shows an association of the COL4A1 gene with CP and suggests a potential role of COL4A1 in the pathogenesis of CP. PMID:26748532

  6. Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population

    Directory of Open Access Journals (Sweden)

    Zhao Nan

    2012-07-01

    Full Text Available Abstract Background Inflammatory mechanisms are important in stroke risk, and genetic variations in components of the inflammatory response have been implicated as risk factors for stroke. We tested the inflammatory gene polymorphisms and their association with ischemic stroke in a Chinese Han population. Methods A total of 1,124 ischemic stroke cases and 1,163 controls were genotyped with inflammatory panel strips containing 51 selected inflammatory gene polymorphisms from 35 candidate genes. We tested the genotype-stroke association with logistic regression model. Results We found two single nucleotide polymorphisms (SNPs in CCL11 were associated with ischemic stroke. After adjusting for multiple testing using false discovery rate (FDR with a 0.20 cut-off point, CCL11 rs4795895 remained statistically significant. We further stratified the study population by their hypertension status. In the hypertensive group, CCR2 rs1799864, CCR5 rs1799987 and CCL11 rs4795895 were nominally associated with increased risk of stroke. In the non-hypertensive group, CCL11 rs3744508, LTC4S rs730012, FCER1B rs569108, TGFB1 rs1800469, LTA rs909253 and CCL11 rs4795895 were associated with ischemic stroke. After correction for multiple testing, CCR2 rs1799864 and CCR5 rs1799987 remained significant in the hypertensive group, and CCL11 rs3744508, LTC4S rs730012, FCER1B rs569108, TGFB1 rs1800469, LTA rs909253 remained significant in the non-hypertensive group. Conclusions Our results indicate that inflammatory genetic variants are associated with increased risk of ischemic stroke in a Chinese Han population, particularly in non-hypertensive individuals.

  7. Genetic association between NRG1 and schizophrenia, major depressive disorder, bipolar disorder in Han Chinese population.

    Science.gov (United States)

    Wen, Zujia; Chen, Jianhua; Khan, Raja Amjad Waheed; Song, Zhijian; Wang, Meng; Li, Zhiqiang; Shen, Jiawei; Li, Wenjin; Shi, Yongyong

    2016-04-01

    Schizophrenia, major depressive disorder, and bipolar disorder are three major psychiatric disorders affecting around 0.66%, 3.3%, and 1.5% of the Han Chinese population respectively. Several genetic linkage analyses and genome wide association studies identified NRG1 as a susceptibility gene of schizophrenia, which was validated by its role in neurodevelopment, glutamate, and other neurotransmitter receptor expression regulation. To further investigate whether NRG1 is a shared risk gene for major depressive disorder, bipolar disorder as well as schizophrenia, we performed an association study among 1,248 schizophrenia cases, 1,056 major depression cases, 1,344 bipolar disorder cases, and 1,248 controls. Totally 15 tag SNPs were genotyped and analyzed, and no population stratification was found in our sample set. Among the sites, rs4236710 (corrected Pgenotye  = 0.015) and rs4512342 (Pallele  = 0.03, Pgenotye  = 0.045 after correction) were associated with schizophrenia, and rs2919375 (corrected Pgenotye  = 0.004) was associated with major depressive disorder. The haplotype rs4512342-rs6982890 showed association with schizophrenia (P = 0.03 for haplotype "TC" after correction), and haplotype rs4531002-rs11989919 proved to be a shared risk factor for both major depressive disorder ("CC": corrected P = 0.009) and bipolar disorder ("CT": corrected P = 0.003). Our results confirmed that NRG1 was a shared common susceptibility gene for major mental disorders in Han Chinese population. © 2016 Wiley Periodicals, Inc. PMID:26888291

  8. 从汉唐碑志的文体演变看韩愈碑志的正与变%On Innovation of Han Yu's Stele Script in Terms of the Style Evolution of Han and Tang Dynasty

    Institute of Scientific and Technical Information of China (English)

    周悦

    2009-01-01

    本文是立足于汉唐碑志的文体演变来考察韩愈碑志的正与变.在汉唐碑志文体的演变历程中,汉代的蔡邕、六朝的庾信、唐代的韩愈是三个不同阶段具有标志意义的人物.蔡邕碑志创造出碑志行文的基本格式,"传"主叙述,"铭"主颂赞,叙颂兼备,语言则崇雅趋骈.庾信碑志在此基础上结构凝固,承袭语言崇雅的取向,由精雅发展为雅丽;形成骈四俪六隔句作对的精美句式.韩愈碑志则在汉魏六朝初盛唐碑志基础上新变:变骈为散,变雅为奇.相对于前代碑志,韩愈碑志多新变,而相对于后世碑志,韩愈碑志被尊为正体.他将碑志文体发展到前所未有的新阶段与新境界,最后完成了碑志文体的演进历程.%The paper focuses on the innovation of Han Yu's stele script in terms of the style evolution of Han and Tang Dynasty.In the course of the style evolution, Cai Yong in Han Dynasty,Yu Xin in Liuchao, Han Yu in Tang Dynasty are the dominant figures.Cai Yong's stele script establishes the basic pattern: "Zhuan" is for narration while "Ming" for compliment,whose language tends to be stable,with the tendency of language being graceful and gorgeous.At this stage,the language was further paralleled,forming the beautiful pattern of 4 paralleled and 6 coupled sentences being away from each other. Han Yu's stele script is innovated on the basis of Han Dynasty,Liuchao and the early stage of prosperous Tang Dynasty:the paralleled pattern tends to be prose and the elegance of the language gave way to being remarkable.Compared with the stele script before him,Han Yu's is full of freshness and compared with it after him,Han Yu's is regarded as classic.He develops the style of stele script into unprecedented stage and completes the process of its innovation.

  9. GeoGebra : hugbúnaðurinn og notagildi hans í kennslu í rúmfræði

    OpenAIRE

    Berglind Svava Arngrímsdóttir

    2009-01-01

    Í ritgerðinni má sjá lýsingu á uppruna hugbúnaðarins GeoGebra. Greint er frá sögu hans og fjallað um uppbyggingu hans, möguleika og notagildi. Markmiðið er að gera vel grein fyrir hugbúnaðinum og gefa dæmi um notagildi hans í grunnskólum hér á landi. Sett eru fram dæmi um notkun hugbúnaðarins í kennslu í elstu bekkjum grunnskólans. Þar sem unnið er út frá hugmyndum í námsbókunum 8-tíu og þrepamarkmiðum aðalnámskrár grunnskólans.

  10. Study of Cesium and Cobalt sorption and diffusion in the geological formation from Novi Han radioactive waste repository

    International Nuclear Information System (INIS)

    The sorption behaviour of Cs and Co in the concentration region of 10-8 to 10-2 M has been studied using samples of the geological formation and ground water from Radioactive waste repository at Novi Han. The mineralogical content, element composition and humic substances of the solid sorbents are determined. The influence on the sorption of parameters such as pH, contact time and nuclide concentration was studied. The distribution coefficients have been determined using a batch technique. The most important parameter influencing the sorption is the nuclide concentration. The diffusion of trace caesium and cobalt in compacted geological formation from the Novi Han has been studied as well. The obtained results for the distribution coefficient are applied as an input for modeling the radionuclide behaviour in the Novi Han geologic formation and the modeling of radionuclide behaviour shows that the risk for the population is low as well as the dose burden for the biosphere and man. (author)

  11. Study on the adult physique with the Heath-Carter anthropometric somatotype in the Han of Xi'an, China.

    Science.gov (United States)

    Yang, Li-Tao; Wang, Ning; Li, Zeng-Xian; Liu, Cui; He, Xin; Zhang, Jian-Fei; Han, Hua; Wen, You-Feng; Qian, Yi-Hua; Xi, Huan-Jiu

    2016-03-01

    The study of somatotypes has important significance for medical and physical anthropology as well as sports science. The aim of this study was to understand the somatotype components of the Han population in Xi'an and compare the somatotypes of the Han and five other nationalities in China. The study sample consisted of 429 people of Han nationality (207 males, 222 females) from Xi'an, China, aged ≥20 years old. The Heath-Carter anthropometric method was employed. We evaluated the differences in age and sex by one-way ANOVA and t test. A comparison of somatotypes between the Han and other nationalities was made using the U test. The results showed that the male and female samples all could be classified as having a mesomorphic endomorph profile. The difference in endomorphy was strongest between sexes in all age groups (P < 0.01). There were prominent differences in mesomorphy and ectomorphy between males and females in the 50-59- and ≥60-year-old age groups. In females, the differences in somatotype components appeared to be distinguished between ages (P < 0.01 or P < 0.05). However, in males, there were prominent differences in somatotype components between the 20-29 year olds and all other age groups (P < 0.01 or P < 0.05) except for between those 20-29 and ≥60 years old in endomorphy. Compared with the other five nationalities, there were prominent differences in somatotype components between males and females. These results suggest that the somatotype of the Han population in Xi'an, China, has a predominantly mesomorphic endomorph profile. The endomorphic component shows distinct differences between ages and genders, respectively. Additionally, there are distinct differences in the somatotype components between Xi'an Han and five other nationalities in China in males and females. PMID:25940679

  12. Die Kläglichkeit feiert Triumphe : "Trivialroman", das neue Buch von Hans Joachim Schädlich

    OpenAIRE

    Soldat, Hans-Georg

    2010-01-01

    Hans-Georg Soldat rezensiert für die Berliner Morgenpost den 1998 im Rowohlt-Verlag erschienen Roman "Trivialroman" von Hans Joachim Schädlich. Keine sinistren Helden hängen rum, sondern Gestalten wie Dogge, Biber, Qualle und Clarissa. Manche monologisieren - »Falls ein Feuer ausbricht, so bewahre Ruhe und rufe nicht "Feuer"«, sagt Qualle in die Stille. Ratte, Wanze und Aal sind nicht da, der Chef und die Äbtissin haben sich schon vor Tagen aus dem Staub gemacht. Trivialroman. Endzeitstimmung...

  13. Inhibition of Sodium-GlucoseCotransporter 2 with dapagliflozin in Han: SPRD rats with polycystic kidney disease

    OpenAIRE

    Rodriguez, Daniel; Kapoor, Sarika; Edenhofer, Ilka; Segerer, Stephan; Riwanto, Meliana; Kipar, Anja; Yang, Ming; Mei, Changlin; Wüthrich, Rudolf P

    2015-01-01

    BACKGROUND/AIMS Dapagliflozin (DAPA) is a selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2) which induces glucosuria and osmotic diuresis. The therapeutic effect of DAPA in progressing stages of polycystic kidney disease (PKD) has not been studied. METHODS We examined the effect of DAPA in the Han: SPRD rat model of PKD. DAPA (10 mg/kg/day) or vehicle (VEH) was administered orally via gavage to 5 week old male Han: SPRD (Cy/+) or control (+/+) rats (n = 8-9 per group) for 5...

  14. TNFR 2 M196R Polymorphism and Acne Vulgaris in Han Chinese:A Case-control Study

    Institute of Scientific and Technical Information of China (English)

    田黎明; 谢红付; 杨婷; 胡耀华; 李吉; 王玮蓁

    2010-01-01

    In this case-control study,the relationship between M196R(676 T→G) variant in exon 6 of tumor necrosis factor receptor type 2(TNFR2) gene and genetic susceptibility of acne vulgaris in Han Chinese was investigated.A total of 93 acne vulgaris patients and 90 healthy subjects from Han Chinese ethnic group were enrolled in this study.Polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) technique was adopted to analyze the single nucleotide polymorphisms(SNPs) of TNFR2 M196R gene,and to ...

  15. Contribution of the Akt2 gene to type 2 diabetes in the Chinese Han population

    Institute of Scientific and Technical Information of China (English)

    SUN Xiu-qin; LUO Ying-ying; AN Ling-wang; CHU Lin; HUO Li-li; HAN Xue-yao; ZHOU Xiang-hai; REN Qian; JI Li-nong

    2011-01-01

    Background The Akt2 protein kinase is thought to be a key mediator of the insulin signal transduction process. Akt2 is suggested to play a role in glucose metabolism and the development or maintenance of proper adipose tissue and islet mass. In order to determine whether the Akt2 gene plays a role in the pathogenesis of type 2 diabetes characterized by insulin resistance, and to further identify if variations in this gene have a relationship with type 2 diabetes, we sequenced the entire coding region and splice junctions of Akt2 and made a further case-control study to explore the association between single-nucleotide polymorphisms (SNPs) in this gene and type 2 diabetes in the Chinese Han population.Methods We selected 23 probands with a type 2 diabetic pedigree whose family members' average onset age was within 25 to 45 years old. The body mass index of all the participants was lower than 28 kg/m2 and all of them were insulin-resistant (the fasting insulin level >100 pmol/L or 16 μlU/ml). The entire coding region and splice junctions of Akt2 were directly sequenced in these 23 probands. SNPs with a frequency of minor allele over 20 percent were selected to be further studied in a case-control study. We chose 743 non-diabetic subjects as the control group and 742 type 2 diabetic patients as the case group. All these subjects were genotyped. A Snapshot Technology Platform (Applied Biosystems) was used for genotyping.Results The Akt2 genes from all 23 subjects were successfully sequenced. We did not identify any mutation in the type 2 diabetic pedigree. Two SNPs were identified, 13010323T>C and 13007939G>T. 13010323T>C was in intron 9, which was the location of rs2304188 reported in Genbank. Its minor allele frequency was 13.04%. 13007939G>T was in the 3'-untranslated region (UTR) of exon 14, which was the location of rs2304186 reported in Genbank. Its minor allele frequency was 34.78%. The allele frequency of rs2304188 and rs2304186 were consistent with

  16. Establishment of the Method of Immunohistochemistry Assay for the Detection of Scrapie in Chinese Short-Tailed Han Sheep by Monoclonal Antibody

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The method of immunohistochemistry assay for the detection of scrapie in Chinese Short-tailed Han sheep was established using monoclonal antibody. Genomic DNA was isolated from Chinese Short-tailed Han sheep blood. Using the polymerase chain reaction technique, PrP27-30 gene sequence was amplified from Chinese Short-tailed Han sheep genomic DNA. By recombinant DNA technology, the recombinant protein of Chinese Short-tailed Han sheep PrP27-30 was obtained. Then, using standard methodology of myeloma cell fusion, a panel of monoclonal antibodies was generated. With mAbs, scrapie in Chinese Short-tailed Han sheep was detected by immunohistochemistry assay. The recombinant protein of Chinese Short-tailed Han sheep PrP27-30 was obtained and a panel of six hybridoma cell lines secreting specific antibodies to Chinese Short-tailed Han sheep PrP27-30 related to scrapie was obtained with one fusion between myeloma Sp2/0 and spleen cells from mice immunized with the purified recombinant protein. Four hybridoma cell lines can be used in immunohistochemistry assay for the detection of scrapie in Chinese Short-tailed Han sheep. So that the special monoclonal antibody developed in author's institute can be used to detect PrPsc of scrapie in Chinese Short-tailed Han sheep by immunohistochemistry in China.

  17. [The disease and treatment of the frontline soldiers in Han dynasty].

    Science.gov (United States)

    Min, Hookie

    2015-04-01

    This paper purports to identify and analyze the medical information of the frontline soldiers in the Northwest borderland provinces of Han Dynasty, especially Juyan and Dunhuang region, through an heuristic reading of the Juyan Bamboo Slips and the Dunhuang Bamboo Slips of the Han Dynasty. My findings are as follows. The most frequent disease found in the bamboo slips was the external injury. The injury of the frontline soldiers mainly occurred from the quarrels among armed soldiers using weapons. The bamboo slips also demonstrate that the quarrels usually arose due to the fierce tension caused by the frontier line service such as heavy guard activity and labour duty. Undernourishment and chronic stress the soldiers suffered might be another reasons. The second most common disease harassing the soldiers was exogenous febrile disease. In most cases reviewed in this paper, the exogenous febrile disease was usually concurrent with complex symptoms such as chills, fever, headache, etc. The bamboo slips show that the exogenous febrile disease was related to the harsh climate of the Northwest provinces, featuring extremely dry weather and the large magnitude of diurnal temperature fluctuations. In addition, the annual temperature range in the Northwest province was huge, fluctuating between very cold and dry winter and very hot and dry summer. The third most common disease this study identified was the disorder of the digestive system and respiratory system. However, these two types of disease were virtually indistinguishable in the bamboo slips, because the ancient Chinese chroniclers did not distinguish them, usually dubbing both diseases simply 'abdominal pain.' It should be mentioned that a few slips mention contagious disease such as dysentery and dermatolosis, and sudden death, as well. Overall, the bamboo slips demonstrate extremely poor status of the soldiers' heath condition and poor medical environment surrounding the soldiers stationing in the Northwest

  18. Maps of Relocation and Poems of Tang Dynasty Poets: Li Bai, Du Fu, and Han Yu

    Directory of Open Access Journals (Sweden)

    羅鳳珠、白璧玲、廖泫銘、范毅軍 、鄭錦全 Feng-Ju Lo,Pi-Ling Pai,Hsiung-Ming Liao,I-Chun Fan,Chin-Chuan Cheng

    2014-04-01

    Full Text Available Geographic environments affect literary contents and genre and thus, since ancient times, geographical area has been used to classify Chinese literature. In 1936 Liang Qichao was keenly aware of the relationship between literature and geography and brought up the idea of “literarygeography”. In 1979 Professor Chen Zhengxiang produced maps of birthplaces of Tang and Song poets to show the shift of Chinese cultural center from north to south. Furthermore, in the pastdecade, the attention to research in literary geography and geographical distribution of writersgradually increased. However, most studies focused on geographical distribution of birthplaces of writers and very few focused on the relationship between poets’ journey and the contents of their writings and their geographic environment. Meanwhile, geographic information system and aerialphotography have developed quickly and have become useful tools for the study of literary geography.Since then, the academic circles in Taiwan have built a solid foundation in this area. While Li Baiand Du Fu were called poetic immortal and poetic sage of the middle and end periods of the heydayof Tang Dynasty, respectively, Han Yu advocated the classical Chinese movement and becameone of the eight great authors of Tang and Song dynasties. Han Yu was also the best representative of Middle Tang poets. While the styles of these three poets differed from each other, they held key positions in the development and evolution of Tang poetry. Their footprints spread all over the countryand greatly affected later developments and contemporary of poetry. This project makes use of the digital Tang Dynasty maps by Tan Qixiang, Tang Dynasty transportation route maps by Yan Gengwang,aerial maps, the All Tang Poems, and chronicles of the poets to build the three poets’ relocation maps and study their poetic literature, language, geography, and interactions with others, in hopesof opening a new research direction

  19. Genetic association between selected cytokine genes and glioblastoma in the Han Chinese population

    International Nuclear Information System (INIS)

    Glioblastoma (GBM) is the most malignant brain tumor. Many abnormal secretion and expression of cytokines have been found in GBM, initially speculated that the occurrence of GBM may be involved in these abnormal secretion of cytokines. This study aims to detect the association of cytokine genes with GBM. We selected seven tag single nucleotide polymorphisms (tSNPs) in six cytokine genes, which previously reported to be associated with brain tumors, and analyzed their association with GBM in a Han Chinese population using χ2 test and genetic model analysis. We found two risk tSNPs and one protective tSNP. By χ2 test, the rs1801275 in IL-4R showed an increased risk of GBM. In the genetic model analysis, the genotype “TC” of rs20541 in IL-13 gene showed an increased risk of GBM in over-dominant model (OR = 2.00; 95% CI, 1.13-3.54, p = 0.015); the genotype “CT” of rs1800871 in the IL-10 gene showed a decrease risk in the over-dominant model (OR = 0.57; 95% CI, 0.33 – 0.97; p = 0.037). The genotype “AG” of rs1801275 in the IL-4R gene showed an increase risk in over-dominant model (OR = 2.29; 95% CI, 1.20 - 4.35; p = 0.0081) We further analyzed whether the six cytokine genes have a different effect on the disease in gender specific population, and found that the allele “G” of rs2243248 in the IL-4 gene showed a decrease risk of GBM in female (OR = 0.35, 95% CI, 0.13 - 0.94, p = 0.0032), but the allele “T” showed a decrease risk in male (OR = 0.30, 95% CI, 0.17 - 0.53, p = 0.0032). Our findings, combined with previously reported results, suggest that cytokine genes have potential role in GBM development, which may be useful to early prognostics for GBM in the Han Chinese population

  20. Association of CTLA-4 gene polymorphisms with sporadic breast cancer in Chinese Han population

    International Nuclear Information System (INIS)

    The host immunogenetic background plays an important role in the development of breast cancer. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a molecule expressed predominantly on activated T cells and is important during the down-regulation of T-cell activation. To evaluate the potential influences of CTLA-4 gene polymorphisms on breast cancer risk, a case-control study was conducted in Han women of Northeast China. We genotyped CTLA-4 variants (-1661 G/A, -658 T/C, -318 T/C, +49 G/A and CT60 G/A) to tag all common haplotypes (≥ 1% frequency) in 117 Chinese breast cancer cases and 148 age/sex matched healthy individuals. Genotypes were determined by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Data was analyzed using the Chi-square test and Haploview software. The frequency of CTLA-4 -1661G allele, -318T allele and CT60G allele carriers was significantly higher in patients than in controls (P = 0.0057, OR 1.91, 95% CI 1.21–3.02; P = 0.0031, OR 2.39, 95% CI 1.34–4.27; P = 0.023, OR 1.52, 95% CI 1.06–2.17, respectively). The -658T allele carrier frequency was significantly lower than in controls (P = 0.0000082, OR 0.17, 95% CI 0.08–0.37), whereas the +49A allele was significantly associated with tumor size in patients (P = 0.0033). Two common CTLA-4 haplotypes, ATCGA and ATCAG, were higher in healthy controls than patients (P = 0.0026, OR 0.17, 95% CI 0.05–0.54; P = 0.034, OR 0.12, 95% CI 0.02–0.92, respectively). A strong association was observed between tumor size and the ACCAA, ACCAG and ACCGA haplotypes (P = 0.0032, P = 0.0000031 and P = 0.017). These results suggest that polymorphisms of the CTLA-4 gene may modify individual susceptibility to and progression of breast cancer in Chinese Han women

  1. Enhanced Diabetes Susceptibility in Community Dwelling Han Elders Carrying the Apolipoprotein E 3/3 Genotype.

    Directory of Open Access Journals (Sweden)

    Chun-Xia Ban

    Full Text Available Despite Apolipoprotein E (ApoE being one of the main apolipoproteins in the blood, the association between its genotype and the high cholesterol or blood glucose levels commonly seen in clinical practice is inconclusive. Such research is also lacking in the Han population. The aim of this study was to investigate the association between APOE genotype, diabetes, and plasma glucose and lipid levels. We included 243 community-dwelling elderly residents in this study. Participant APOE genotypes were assessed and were simultaneously tested for weight, height, blood glucose, triglycerides, cholesterol, and high- and low-density lipoprotein. In addition, gender, age, years of education, cognitive function, and medical history was recorded. Subjects were divided into 3 groups based on APOE genotype: APOE ε2 group (ε2/ε2 and ε2/ε3, APOE ε3 group (ε3/ε3, and APOE ε4 group (ε2/ε4, ε3/ε4 and ε4/ε4. Comparisons between groups were conducted for the incidence of diabetes, high blood pressure, and dementia, as well as for differences in body-mass index, fasting plasma glucose, and blood lipids. The APOE ε3/ε3 genotype exhibited the highest frequency (70.4% among the subjects. Participants in the APOE ε3 group demonstrated significantly higher levels of fasting plasma glucose than those in the APOE ε2 and APOE ε4 groups (P<0.05. The APOE ε3 group had slightly higher abnormal fasting plasma glucose values than did the APOE ε2 group (P = 0.065. Furthermore, the APOE3 genotype was significantly correlated with both fasting plasma glucose level and glucose abnormality (P< 0.05 and trended toward statistically significant correlation with diabetes (P = 0.082. The correlation between APOE2 and low low-density lipoprotein levels also approached statistical significance (P = 0.052. Thus, elderly community dwelling residents of Han ethnicity carrying the APOE ε3/ε3 genotype might have higher plasma glucose levels and a higher occurrence of

  2. Hans van Ginkel: On the Vision, History and Status of the Regional Centres of Expertise in ESD Programme

    Science.gov (United States)

    Glasser, Harold

    2008-01-01

    Professor Hans van Ginkel, Rector of the United Nations University, Tokyo, (1997-2007) and president of the International Association of Universities (2000-2004), pioneered the concept of Regional Centers of Expertise in Education for Sustainable Development (RCEs) as a strategy for meeting the goals of the United Nations Decade of Education for…

  3. Pärast rahvahääletust Iirimaal - Qua vadis, euroopa? / Hans-Gert Pöttering

    Index Scriptorium Estoniae

    Pöttering, Hans-Gert, 1945-

    2008-01-01

    Euroopa Parlamendi presidendi Hans-Gert Pötteringi sõnul reformilepingu vastu võtmine on hädavajalik selleks, et EL saaks 21. sajandil kaitsta oma huve ja väärtusi. Lissaboni lepingus ettenähtud reformideta on uute riikide liitumine EL-ga vaevalt et võimalik

  4. El derecho de compensación por trabajo doméstico en el régimen de separación de bienes del cc y en la LREMV: análisis comparativo

    OpenAIRE

    Montes Rodríguez, María Pilar

    2015-01-01

    La dedicación exclusiva de unos de los cónyuges al trabajo doméstico le atribuye, en el Código civil español, el derecho a una compensación económica cuando el régimen económico matrimonial es el de separación de bienes. En la LREMV el trabajo doméstico no sólo se considera contribución a las cargas del matrimonio sino que también da lugar a un derecho de compensación Exclusive dedication of one of the spouses to domestic work attributed to him in the Spanish Civil Code, ...

  5. La virtud y el comercio en el pensamiento de Domingo de Soto: las prácticas comerciales, el carácter y el bien común

    OpenAIRE

    Azevedo-Alves, A. (André); Moreira, J M

    2014-01-01

    El artículo ahonda en la obra de Domingo de Soto, teólogo, filósofo y especialista en ética del siglo XVI, y examina su propuesta, basada en la virtud, de una evaluación ética del comercio dentro de un marco aristotélico-tomista que permite la articulación de los negocios y el bien común. Presta particular atención al énfasis fundamental que Soto pone en la distinción entre el comercio como actividad y la conducta específica de las personas que se dedican a la actividad comercial. La distinci...

  6. Valérie Deplaigne, Les femmes nobles dans les conflits de transmission de biens aux lendemains de la bataille d’Azincourt, en pays de droit coutumier français

    Directory of Open Access Journals (Sweden)

    Valérie Deplaigne

    2008-07-01

    Full Text Available Faisant suite à un premier travail de recherche portant sur le patrimoine, l’héritage et la transmission des biens d’une héritière noble à la fin du XVe siècle, ce mémoire de deuxième année de Master a pour ambition de sortir de l’aspect monographique alors embrassé pour tenter une approche comparatiste à partir de l’étude de différents cas. Le cadre chronologique choisi est celui de « l’après-Azincourt », moment propice à la plus grande participation des femmes nobles à la vie publique et à ...

  7. Attitudes et consentement à payer des consommateurs vis-à-vis du bien-être animal : une application au cas de la viande bovine en France et en Espagne

    OpenAIRE

    Weisslinger, Delphine

    2015-01-01

    L’intérêt pour le bien-être animal (BEA) se manifeste de plus en plus dans nos sociétés européennes, et peut conduire à de nouvelles attentes de la part les consommateurs. Cette étude s’intéresse aux attitudes et au Consentement à Payer (CAP) des consommateurs pour de la viande bovine certifiée « respectueuse du BEA », à l’aide d’une enquête menée auprès de 1213 consommateurs répartis dans quatre régions en France et en Espagne. La mesure des degrés d’importance et de confiance accordés à 11 ...

  8. Le bien-être au travail en mutation chez les enseignants - une nouvelle approche guidée par la théorie culturelle et historique de l’activité

    OpenAIRE

    Launis, Kirsti; Koli, Annarita

    2014-01-01

    De nombreuses recherches ont révélé que le stress et l’épuisement au travail des enseignants sont en progression. Il s’agit manifestement d’un grave problème constituant une menace pour leur santé et leur bien-être. Au cours de cette étude, les chercheurs ont mesuré les diverses sollicitations exercées dans le travail d’enseignantes et présenté des propositions pour améliorer leur travail et ses conditions de réalisation. Ces propositions ont été prises en compte dans des programmes de format...

  9. Kroppslighet og jomfrukur i Hans E. Kincks tragedie Den sidste Gjest (1910

    Directory of Open Access Journals (Sweden)

    Roy Eriksen

    2011-06-01

    Full Text Available In his play on Pietro Aretino (1492-1556, the Norwegian dramatist and novelist Hans E. Kinck (1865-1926 focuses on his character's relationship to the body and use of young women, in particular the young girl, Perina. A writer of great repute among his contemporaries Aretino is today known for his letters, plays, scandalous dialogues and pornographic sonnets in which grotesque images of the body are frequent. Kinck turns the Italian letterato both into a tragic victim of his own drives and a ruthless victimizer, although he in the process must avoid many aspects of Aretino's writing and character that it would be impossible to reproduce in print at the time, but in so doing he both rejects and redescripts metaphors for the body and writing we recognize from Rabelais, Shakespeare, and Nashe. Aretino's famed obesity and incessant appetite become metaphors for Aretino's struggle for fame and immortality, but are also signs of the fetishization and expenditure of young girls in Early Modern Venetian society, and in the Europe of Kinck's own time. This reading "against the grain" tries to ease out the actuality of the play and the reason for the different data Kinck gives for Perina's age in the play and in En Penneknegt (1911.

  10. A Novel COL4A5 Mutation Identified in a Chinese Han Family Using Exome Sequencing

    Directory of Open Access Journals (Sweden)

    Xiaofei Xiu

    2014-01-01

    Full Text Available Alport syndrome (AS is a monogenic disease of the basement membrane (BM, resulting in progressive renal failure due to glomerulonephropathy, variable sensorineural hearing loss, and ocular anomalies. It is caused by mutations in the collagen type IV alpha-3 gene (COL4A3, the collagen type IV alpha-4 gene (COL4A4, and the collagen type IV alpha-5 gene (COL4A5, which encodes type IV collagen α3, α4, and α5 chains, respectively. To explore the disease-related gene in a four-generation Chinese Han pedigree of AS, exome sequencing was conducted on the proband, and a novel deletion mutation c.499delC (p.Pro167Glnfs*36 in the COL4A5 gene was identified. This mutation, absent in 1,000 genomes project, HapMap, dbSNP132, YH1 databases, and 100 normal controls, cosegregated with patients in the family. Neither sensorineural hearing loss nor typical COL4A5-related ocular abnormalities (dot-and-fleck retinopathy, anterior lenticonus, and the rare posterior polymorphous corneal dystrophy were present in patients of this family. The phenotypes of patients in this AS family were characterized by early onset-age and rapidly developing into end-stage renal disease (ESRD. Our discovery broadens the mutation spectrum in the COL4A5 gene associated with AS, which may also shed new light on genetic counseling for AS.

  11. Replication of Han Chinese GWAS loci for schizophrenia via meta-analysis of four independent samples.

    Science.gov (United States)

    Xiao, Xiao; Li, Ming

    2016-04-01

    Schizophrenia is a highly heritable psychiatric disorder with unclear aetiology. Recent genome-wide association studies (GWAS) in European populations have reported numerous susceptibility variants, while GWAS in East Asians also identified several risk loci but with fewer independent replications. Here we focus on nine single nucleotide polymorphisms (SNPs) which have shown genome-wide significant associations with schizophrenia in previous Han Chinese GWAS, and we tend to replicate the associations in four independent samples of East Asian origin including a total of 3977 cases and 5589 controls. The results showed that rs10489202 in MPC2 (BRP44) is significantly associated with schizophrenia in these East Asian replication samples (one-tailed P=5.75×10(-3), OR=1.12), and further meta-analysis after including previous GWAS data yielded a genome-wide significant association (two-tailed P=1.11×10(-10), OR=1.19), adding further support for the involvement of this locus in the genetic risk of schizophrenia, and future studies regarding the underlying molecular mechanisms of the risk association are necessary. PMID:26899211

  12. Long-term follow-up of HAN-1, an acute plutonium oxide inhalation case

    International Nuclear Information System (INIS)

    The International Commission on Radiation Protection (ICRP) has recommended that plutonium oxide be designated an inhalation class Y material, indicating that a 500-day clearance half-time from the lung is adequate for radiation protection purposes. Based on extensive data obtained from one particular inhalation case (referred to here as HAN-1), and supported by somewhat less detailed data in nine other cases, an argument has been put forth that substantially longer clearance half-times may not be uncommon for Pu oxide. This has led to the tentative identification of a ''super class Y'' form of Pu which has been factored into worker monitoring programs at the US Department of Energy's Hanford Site. In addition, the United States Transuranium Registry autopsy work has indicted evidence to support the super class Y case. The particular case described in this paper was the key case which caused the Hanford internal dosimetry staff to seriously consider super class Y material. This paper includes data from long-term follow up monitoring as well as early data for calculating intakes for comparisons with secondary limits. 13 refs, 2 figs., 1 tab

  13. Making space for criminalistics: Hans Gross and fin-de-siècle CSI

    Science.gov (United States)

    Burney, Ian; Pemberton, Neil

    2013-01-01

    This article explores the articulation of a novel forensic object—the ‘crime scene’—and its corresponding expert—the investigating officer. Through a detailed engagement with the work of the late nineteenth-century Austrian jurist and criminalist Hans Gross, it analyses the dynamic and reflexive nature of this model of ‘CSI’, emphasising the material, physical, psychological and instrumental means through which the crime scene as a delineated space, and its investigator as a disciplined agent operating within it, jointly came into being. It has a further, historiographic, aim: to move away from the commonplace emphasis in histories of forensics on fin-de-siècle criminology and toward its comparatively under-explored contemporary, criminalistics. In so doing, it opens up new ways of thinking about the crime scene as a defining feature of our present-day forensic culture that recognise its historical contingency and the complex processes at work in its creation and development. PMID:23036861

  14. The common variant rs11646213 is associated with preeclampsia in Han Chinese women.

    Directory of Open Access Journals (Sweden)

    Ji-peng Wan

    Full Text Available BACKGROUND: Preeclampsia, characterized by hypertension and proteinuria, is a multifactorial disease caused by complex interactions between environmental and genetic factors. A recent genome-wide association study of blood pressure reported an association between hypertension and rs11646213. This study evaluated the association between preeclampsia and rs11646213. METHODS: A total of 454 cases and 460 controls were recruited to participate in this study. The single nucleotide polymorphism (SNP rs11646213 was genotyped by polymerase chain reaction (PCR and direct sequencing. RESULTS: The allele frequency of rs11646213 was significantly different between the preeclampsia and control groups (P = 0.017, OR = 1.36, 95% CI = 1.06-1.76. Differences were particularly significant in the severe preeclampsia subgroup (P = 0.002, OR = 1.54, 95% CI = 1.17-2.03 and the early-onset preeclampsia subgroup (P = 0.004, OR = 1.57, 95% CI = 1.16-2.13. Genotyping analysis showed that the T allele of rs11646213 could confer a risk for preeclampsia, severe preeclampsia and early-onset preeclampsia. CONCLUSIONS: Rs11646213 upstream of the CDH13 gene is associated with preeclampsia in Han Chinese women.

  15. Common variant rs7579169 is associated with preeclampsia in Han Chinese women.

    Science.gov (United States)

    Guo, L F; Wang, Z H; Wang, Y F

    2016-01-01

    As a heterogeneous group of disorders in pregnancy, many genetic factors are involved in the development of preeclampsia. The single nucleotide polymorphism (SNP) rs7579169, located on chromosome 2q14.2, has been shown to be associated with pregnancy-induced hypertension in Europeans. In this study, we examined whether the SNP rs7579169 is associated with the susceptibility to preeclampsia through a case-control research model in Han Chinese women. Genotypes of 145 patients with preeclampsia and 150 healthy pregnant subjects were identified by direct sequencing. The correlation between the rs7579169 genotype and the susceptibility to preeclampsia was evaluated using an unconditional logistic regression model. Although there were no differences of having the rs7579169 SNP between early onset and late onset preeclampsia, patients carrying the CT or TT genotype were more likely to develop preeclampsia than those carrying the CC genotype (CT vs CC: OR = 1.76, 95%CI = 1.07-2.87, P Chinese women. PMID:27173354

  16. Mitochondrial genome variations and functional characterization in Han Chinese families with schizophrenia.

    Science.gov (United States)

    Bi, Rui; Tang, Jinsong; Zhang, Wen; Li, Xiao; Chen, Shi-Yi; Yu, Dandan; Chen, Xiaogang; Yao, Yong-Gang

    2016-03-01

    The relationship between mitochondrial DNA (mtDNA) variants and schizophrenia has been strongly debated. To test whether mtDNA variants are involved in schizophrenia in Han Chinese patients, we sequenced the entire mitochondrial genomes of probands from 11 families with a family history and maternal inheritance pattern of schizophrenia. Besides the haplogroup-specific variants, we found 11 nonsynonymous private variants, one rRNA variant, and one tRNA variant in 5 of 11 probands. Among the nonsynonymous private variants, mutations m.15395 A>G and m.8536 A>G were predicted to be deleterious after web-based searches and in silico program affiliated analysis. Functional characterization further supported the potential pathogenicity of the two variants m.15395 A>G and m.8536 A>G to cause mitochondrial dysfunction at the cellular level. Our results showed that mtDNA variants were actively involved in schizophrenia in some families with maternal inheritance of this disease. PMID:26822593

  17. Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese

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    Lai Te-Jen

    2008-05-01

    Full Text Available Abstract Background Monoamine oxidase A (MAOA is a mitochondrial enzyme involved in degrading several different biological amines, including serotonin. Although several pieces of evidence suggested that MAOA is important in the etiology of bipolar affective disorder (BPD, associations for markers of the MAOA gene with BPD were not conclusive and the association has not been investigated in Taiwanese population. This study was designed to illustrate the role of MAOA in the etiology of BPD in Han Chinese. Methods Two markers, a dinucleotide polymorphism in exon 2 and a functional uVNTR on the promoter of the MAOA gene, were used to study the genetic association in 108 unrelated patients with BPD and 103 healthy controls. Allelic distributions of two polymorphisms were analyzed and, caused the MAOA located at X chromosome, haplotype association was performed using haplotype unambiguously assigned in male participants. Results While no difference in allelic distributions of two MAOA polymorphisms was found, the risk haplotype 114S was associated with BPD in male patients (P = 0.03. The significance, however, was not found in female patients with 114S haplotype. Conclusion Results from this study suggest that MAOA may have a gender-specific and small effect on the etiology of BPD in Taiwan. Due to the limited sample size, results from this study need to be confirmed in replicates.

  18. Mandibular incisive canal in Han Chinese using cone beam computed tomography.

    Science.gov (United States)

    Kong, N; Hui, M; Miao, F; Yuan, H; Du, Y; Chen, N

    2016-09-01

    The aim of this study was to provide reference information for implantology and chin bone harvesting in people of Han Chinese ethnicity by studying the mandibular incisive canal (MIC) using cone beam computed tomography (CBCT). Fifty subjects were included in the study. CBCT scans were obtained for all subjects, and 22 also underwent panoramic radiography to evaluate the visibility of the MIC. The CBCT data of the 50 subjects were reconstructed to measure MIC diameter, length, and location within the mandible. A MIC was identified in 38.6% of panoramic radiographs, with good clarity in 13.6%, while a MIC was identified in 100% of CBCT images, with good clarity in 63.6%. The diameter of the MIC decreased from origin to end. The left and right average MIC lengths were 17.84mm and 17.73mm, respectively. The MIC was close to the buccal cortical border and lower margin of the mandible. In conclusion, the MIC is an anatomical structure in the mandible that can be identified reliably with CBCT. On insertion, implants should be inclined slightly towards the lingual aspect of the anterior mandible to protect the MIC. The chin bone harvesting depth should be limited to 4mm; the harvesting site can be adjusted to the region above or below the MIC. PMID:27184354

  19. SOBRE UNA PROPUESTA DE LECTURAS DE DIEZ CUENTOS DE HANS CHRISTIAN ANDERSEN

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    Ronald Campos López

    2009-01-01

    Full Text Available Se presenta una propuesta metodológica de lecturas de diez cuentos de Hans Christian Andersen, aplicable a una situación de aula de estudiantes de quinto grado de la Escuela de San Rafael de Coronado. Dicho enfoque se orienta desde una perspectiva del valor pragmático de la literatura, en donde el niño y la niña se constituyan a sí mismos como lectores-estudiantesindividuos sociales simultáneamente, a medida que ejecutan su capacidad crítico-analítica, abstracta, simbólica, comparativa, lingüística y representativa sobre la discursividad hegemónica de la identidad y en contra de la dogmática función social del abordaje metodológico cotidiano de los textos literarios aún en las aulas costarricenses. Es por ello que resultan imperativos lecturas y análisis (deconstructivos de textos, literarios propiamente en este caso, los cuales problematicen la institucionalidad del lenguaje en los procesos de enseñanza y aprendizaje.

  20. Response to Hans Thulesius and Vivian B. Martin on Ekins (2011

    Directory of Open Access Journals (Sweden)

    Richard Ekins, Ph.D., FRSA

    2011-12-01

    Full Text Available I appreciate the valuable comments from Hans Thulesius and Vivian Martin. Both reviewers usefully and most helpfully pinpoint salient issues to be considered in forging future routes for my ongoing research in jazz historiography. I agree with Vivian Martin that ‘authenticating’ works better for early jazz and first wave USA revivalism (including Bunk Johnson and would like to say that at the time I wrote the abstract, I was favouring ‘managing authenticity’ over ‘authenticating’ as the core category in order to provide a more embracive category within which to consider early jazz, the 1940s New Orleans jazz revival (including Bunk Johnson, and the world-wide New Orleans jazz revivalist movement which continues to this day. I have, indeed, written elsewhere of all the various phases of New Orleans style jazz considered in terms of the core category/basic social process of ‘authenticating’, e.g., ‘Authenticity as Authenticating – The Case of New Orleans Jazz Revivalism: An Approach from Grounded Theory and Social World Analysis’ (Ekins, forthcoming.

  1. Association of HLA-DQ with Idiopathic Dilated Cardiomyopathy in a Northern Chinese Han Population

    Institute of Scientific and Technical Information of China (English)

    WeiLiu; WeiminLi; NinglingSun

    2004-01-01

    Autoimmune mechanisms are likely involved in the pathogenesis of idiopathic dilated cardiomyopathy (IDC) and components of MHC may serve as markers for the propensity to develop immune-mediated myocardial damage. This study was conducted to investigate the possible association between HLA-DQA1, -DQB1 alleles and IDC in Han population from northern China by using PCR-based sequence-specific primer (PCR-SSP) technique for HLA genotyping. Among 68 unrelated IDC patients, 4 probands of IDC pedigrees and 100 healthy controls, we found that the alleles of HLA-DQAI*0501 and HLA-DQBI*0303 conferred susceptibility to IDC while HLA-DQAI*0201 and HLA-DQBI*0502, *0504 alleles were in negative association with IDC. The serine at position 57 (SERs7) in the exon of HLA-DQBI*0502 and *0504 was confirmed in our experiment as a marker for resistance to IDC. The results suggest that HLA-DQ polymorphism may be involved in the pathogenesis of IDC. Cellular & Molecular Immunology.

  2. Association of HLA-DQ with Idiopathic Dilated Cardiomyopathy in a Northern Chinese Han Population

    Institute of Scientific and Technical Information of China (English)

    Wei Liu; Weimin Li; Ningling Sun

    2004-01-01

    Autoimmune mechanisms are likely involved in the pathogenesis of idiopathic dilated cardiomyopathy (IDC) and components of MHC may serve as markers for the propensity to develop immune-mediated myocardial damage. This study was conducted to investigate the possible association between HLA-DQA1, -DQB1 alleles and IDC in Han population from northern China by using PCR-based sequence-specific primer (PCR-SSP) technique for HLA genotyping. Among 68 unrelated IDC patients, 4 probands of IDC pedigrees and 100 healthy controls, we found that the alleles of HLA-DQA1*0501 and HLA-DQB1*0303 conferred susceptibility to IDC while HLA-DQA1*0201 and HLA-DQB1*0502, *0504 alleles were in negative association with IDC. The serine at position 57 (SER57) in the exon of HLA-DQB1*0502 and *0504 was confirmed in our experiment as a marker for resistance to IDC. The results suggest that HLA-DQ polymorphism may be involved in the pathogenesis of IDC.

  3. Sequence Variants of ADIPOQ and Association with Type 2 Diabetes Mellitus in Taiwan Chinese Han Population

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    Ming-Kai Tsai

    2014-01-01

    Full Text Available Diabetes is a serious global health problem. Large-scale genome-wide association studies identified loci for type 2 diabetes mellitus (T2DM, including adiponectin (ADIPOQ gene and transcription factor 7-like 2 (TCF7L2, but few studies clarified the effect of genetic polymorphisms of ADIPOQ and TCF7L2 on risk of T2DM. We attempted to elucidate association between T2DM and polymorphic variations of both in Taiwan’s Chinese Han population, with our retrospective case-control study genotyping single nucleotide polymorphisms (SNPs in ADIPOQ and TCF7L2 genes both in 149 T2DM patients and in 139 healthy controls from Taiwan. Statistical analysis gauged association of these polymorphisms with risk of T2DM to show ADIPOQ rs1501299 polymorphism variations strongly correlated with T2DM risk (P=0.042, with rs2241766 polymorphism being not associated with T2DM (P=0.967. However, both polymorphisms rs7903146 and rs12255372 of TCF7L2 were rarely detected in Taiwanese people. This study avers that ADIPOQ rs1501299 polymorphism contributes to risk of T2DM in the Taiwanese population.

  4. Seeking the truth: Hans Blix speaks to CNN's Christiane Amanpour on disarming Iraq

    International Nuclear Information System (INIS)

    Speaking on the anniversary of the United States' invasion of Iraq, originally declared as a preemptive strike against a madman ready to deploy weapons of mass destruction (WMD), the man first charged with finding those weapons said that the US government has 'the same mind frame as the witch hunters of the past' - looking for evidence to support a foregone conclusion. 'There were about 700 inspections, and in no case did we find weapons of mass destruction,' said Hans Blix, the Swedish diplomat called out of retirement to serve as the United Nations' chief weapons inspector from 2000 to 2003; from 1981 to 1997 he headed the International Atomic Energy Agency (IAEA). 'We went to sites [in Iraq] given to us by intelligence, and only in three cases did we find something' - a stash of nuclear documents, some Vulcan boosters, and several empty warheads for chemical weapons. More inspections were required to determine whether these findings were the 'tip of the iceberg' or simply fragments remaining from that deadly iceberg's past destruction, Blix said he told the United Nations Security Council. However, his work in Iraq was cut short when the United States and the United Kingdom took disarmament into their own hands in March of 2003

  5. Prevalence of diabetes among Han, Manchu and Korean ethnicities in the Mudanjiang area of China: a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Feng Yan

    2012-01-01

    Full Text Available Abstract Background Rapid socioeconomic development resulting in changing lifestyles and life expectancy appears to be accompanied by an increasing prevalence of type 2 diabetes. Genetic predisposition related to ethnicity is a major determinant of diabetes risk. This study investigates the prevalences of diabetes and prediabetes in different ethnic populations residing in the Mudanjiang area located in the northeast of China. Methods A cross-sectional survey was carried out among Han, Manchu and Korean Chinese aged 20 years or older. Diabetes and prediabetes were diagnosed using standard oral glucose tolerance tests. Results The prevalence of diabetes in Manchu (8.39% and Korean Chinese (9.42% was significantly lower than that in Han (12.10%. The prevalence of prediabetes was 18.96%, 19.36% and 20.47% in Han, Manchu and Korean populations, respectively. Korean Chinese had a lower prevalence of isolated impaired fasting glucose and higher prevalence of isolated impaired glucose tolerance than the other two ethnic groups. Most patients with diabetes, especially ethnic minority patients, were undiagnosed. A multiple logistic regression analysis showed that age, family history of diabetes, control of diet, self-monitoring of weight, central obesity, increased heart rate, hypertension, elevated plasma triglyceride level, elevated plasma low-density lipoprotein cholesterol, and Han ethnicity were significantly associated with an increased risk of diabetes. Further, Manchu Chinese were found to have the lowest risk of diabetes. Conclusions Our study indicates that diabetes is a major public health problem in the Mudanjiang area of China. Ethnicity plays a role in the different prevalences of diabetes and prediabetes among the three ethnic groups. Diabetes is less prevalent among Manchu Chinese compared with Han and Korean Chinese.

  6. Analysis of 24 Y chromosomal STR haplotypes in a Chinese Han population sample from Henan Province, Central China.

    Science.gov (United States)

    Shi, Meisen; Liu, Yaju; Zhang, Juntao; Bai, Rufeng; Lv, Xiaojiao; Ma, Shuhua

    2015-07-01

    We analyzed haplotypes for 24 Y chromosomal STRs (Y-STRs), including 17 Yfiler loci (DYS19, DYS385a/b, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DY438, DYS439, DYS448, DYS456, DYS458, DYS635 and Y-GATA-H4) and 7 additional STRs (DYS388, DYS444, DYS447, DYS449, DYS522 and DYS527a/b) in 1100 unrelated Chinese Han individuals from Henan Province using AGCU Y24 STR kit systems. The calculated average gene diversity (GD) values ranged from 0.4105 to 0.9647 for the DYS388 and DYS385a/b loci, respectively. The discriminatory capacity (DC) was 72.91% with 802 observed haplotypes using 17 Yfiler loci, by the addition of 7 Y-STRs to the Yfiler system, the DC was increased to 79.09% while showing 870 observed haplotypes. Among the additional 7 Y-STRs, DYS449, DYS527a/b, DYS444 and DYS522 were major contributors to enhancing discrimination. In the analysis of molecular variance, the Henan Han population clustered with Han origin populations and showed significant differences from other Non-Han populations. In the present study, we report 24 Y-STR population data in Henan Han population, and we emphasize the need for adding additional markers to the commonly used 17 Yfiler loci to achieve more improved discriminatory capacity in a population with low genetic diversity. PMID:25864156

  7. Identification of novel mutations in Chinese Hans with autosomal dominant polycystic kidney disease

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    Yu Chaowen

    2011-12-01

    Full Text Available Abstract Background Autosomal dominant polycystic kidney disease (ADPKD is the most common inherited renal disease with an incidence of 1 in 400 to 1000. The disease is genetically heterogeneous, with two genes identified: PKD1 (16p13.3 and PKD2 (4q21. Molecular diagnosis of the disease in at-risk individuals is complicated due to the structural complexity of PKD1 gene and the high diversity of the mutations. This study is the first systematic ADPKD mutation analysis of both PKD1 and PKD2 genes in Chinese patients using denaturing high-performance liquid chromatography (DHPLC. Methods Both PKD1 and PKD2 genes were mutation screened in each proband from 65 families using DHPLC followed by DNA sequencing. Novel variations found in the probands were checked in their family members available and 100 unrelated normal controls. Then the pathogenic potential of the variations of unknown significance was examined by evolutionary comparison, effects of amino acid substitutions on protein structure, and effects of splice site alterations using online mutation prediction resources. Results A total of 92 variations were identified, including 27 reported previously. Definitely pathogenic mutations (ten frameshift, ten nonsense, two splicing defects and one duplication were identified in 28 families, and probably pathogenic mutations were found in an additional six families, giving a total detection level of 52.3% (34/65. About 69% (20/29 of the mutations are first reported with a recurrent mutation rate of 31%. Conclusions Mutation study of PKD1 and PKD2 genes in Chinese Hans with ADPKD may contribute to a better understanding of the genetic diversity between different ethnic groups and enrich the mutation database. Besides, evaluating the pathogenic potential of novel variations should also facilitate the clinical diagnosis and genetic counseling of the disease.

  8. Network-assisted analysis of primary Sjögren's syndrome GWAS data in Han Chinese.

    Science.gov (United States)

    Fang, Kechi; Zhang, Kunlin; Wang, Jing

    2015-01-01

    Primary Sjögren's syndrome (pSS) is a complex autoimmune disorder. So far, genetic research in pSS has lagged far behind and the underlying biological mechanism is unclear. Further exploring existing genome-wide association study (GWAS) data is urgently expected to uncover disease-related gene combination patterns. Herein, we conducted a network-based analysis by integrating pSS GWAS in Han Chinese with a protein-protein interactions network to identify pSS candidate genes. After module detection and evaluation, 8 dense modules covering 40 genes were obtained for further functional annotation. Additional 31 MHC genes with significant gene-level P-values (sigMHC-gene) were also remained. The combined module genes and sigMHC-genes, a total of 71 genes, were denoted as pSS candidate genes. Of these pSS candidates, 14 genes had been reported to be associated with any of pSS, RA, and SLE, including STAT4, GTF2I, HLA-DPB1, HLA-DRB1, PTTG1, HLA-DQB1, MBL2, TAP2, CFLAR, NFKBIE, HLA-DRA, APOM, HLA-DQA2 and NOTCH4. This is the first report of the network-assisted analysis for pSS GWAS data to explore combined gene patterns associated with pSS. Our study suggests that network-assisted analysis is a useful approach to gaining further insights into the biology of associated genes and providing important clues for future research into pSS etiology. PMID:26686423

  9. Hans A. Bethe Prize: Neutron Stars and Core-Collapse Supernovae

    Science.gov (United States)

    Lattimer, James

    2015-04-01

    Core-collapse supernovae lead to the formation of neutron stars, and both are sensitive to the dense matter equation of state. Hans Bethe first recognized that the matter in the collapsing core of a massive star has a relatively low entropy which prevents nuclear dissociation until nuclei merge near the nuclear saturation density. This recognition means that collapse continues until the core exceeds the saturation density. This prediction forms the foundation for modern simulations of supernovae. These supernovae sample matter up to about twice nuclear saturation density, but neutron stars are sensitive to the equation of state both near the saturation density and at several times higher densities. Two important recent developments are the discovery of two-solar mass neutron stars and refined experimental determinations of the behavior of the symmetry energy of nuclear matter near the saturation density. Combined with the assumption of causality, they imply that the radii of observed neutron stars are largely independent of their mass, and that this radius is in the range of 11 to 13 km. These theoretical results are not only consistent with expectations from theoretical studies of pure neutron matter, but also accumulated observations of both bursting and cooling neutron stars. In the near future, new pulsar timing data, which could lead to larger measured masses as well as measurements of moments of inertia, X-ray observations, such as from NICER, of bursting and other sources, and gravitational wave observations of neutron stars in merging compact binaries, will provide important new constraints on neutron stars and the dense matter equation of state. DOE DE-FG02-87ER-40317.

  10. Reproductive senescence, fertility and reproductive tumour profile in ageing female Han Wistar rats.

    Science.gov (United States)

    Mitchard, Terri L; Klein, Stephanie

    2016-01-01

    A study using vehicle administration in 104 female rats investigated reproductive aging in Han Wistar rats as a useful tool to interprete carcinogenicity studies where hormonal patterns are perturbated. From 16 weeks of age oestrous cycles were monitored every 6 weeks to investigate reproductive ageing. A subset of 20 females was used to assess fertility at 21 months of age. The animals were necropsied after 106-107 weeks on study and female reproductive organs, mammary glands and pituitary glands were examined for hyperplasias and/or tumours. The majority of rats had regular oestrous cycles up to 6 months of age. After this age, there was a rapid decline in the number of rats with regular oestrous cycles and an increase in irregular cycles and cycles in persistent di-oestrus with an occasional pro-oestrus. By the end of the study, the majority of animals were acyclic and the few remaining cyclic animals had irregular cycles. In the fertility assessment, 19/20 animals mated but only four animals became pregnant. These pregnant animals had normal numbers of corpora lutea of pregnancy but had high pre-implantation losses and could not sustain a viable pregnancy. 65 animals (62.5%) showed adenomas and/or pituitary hyperplasia in the pituitary gland at necropsy. The pituitary tumours were likely to be prolactin secreting that give rise to pseudopregnancy and mammary tumours, demonstrated by the fact that 43/65 (66%) of the affected animals had histopathological signs of these conditions. Multiple corpora lutea were found in 61% of all animals at time of termination. Only one uterine tumour was seen in this study probably due to lack of persistent oestrus seen in these animals. PMID:26655996

  11. The relationship of haplotype in lactotransferrin and its expression levels in Chinese Han ovarian cancer

    Institute of Scientific and Technical Information of China (English)

    Lanqin Cao; Yanhong Zhou; Xin Li; Hong Yi

    2011-01-01

    Chromosomal DNA sequence polymorphisms may contribute to individuality,confer risk for diseases,and most commonly are used as genetic markers in association study.The iron-binding protein lactoferrin inhibits bacterial growth by sequestering essential iron and also exhibits antitumor,anti-inflammatory,and immunoregulatory activities.The gene coding for lactotransferrin (LTF) is polymorphic,with the occurrence of several common alleles in the general population.This genetically determined variation can affect LTF functions.In this study,we determined the distribution of LTF gene polymorphisms (rs1126477,rs1126478,rs2073495,and rs9110) in the Chinese Han population and investigated whether these polymorphisms were associated with increased risk of ovarian carcinoma in the Chinese.It was found that the rs1126477 was correlated significantly with ovarian cancer.The frequency of A allele of rs1126477 was significantly higher in 700 ovarian cancer patients compared with that in the control group of 700 cases (P < 0.01,x2=6.79).The frequency of AA genotype was significantly higher in ovarian cancer patients compared with that in the control group (P < 0.05,x2=6.49).AA genotype is the risk factor of ovarian cancer.The odds ratio (OR) was 2.24 and the 95% confidence interval (CI) was 1.08-4.59,respectively.The ‘A-G-C-C' haplotype constructed with rs1126477,rs1126478,rs2073495,and rs9110 was the risk factor to be ovarian cancer.The expression of LTF gene was lower in individuals with ‘A-G-C-C' haplotype compared with that in individuals without ‘A-G-C-C' haplotype.These findings suggested that rs1126477 could play important roles in ovarian carcinoma physiological processes in the Chinese.

  12. Macromineral requirements of Dorper×thin-tailed Han crossbred female lambs

    Institute of Scientific and Technical Information of China (English)

    JI Shou-kun; XU Gui-shan; DIao Qi-yu; DenG Kai-dong; JIanG Cheng-gang; TU Yan; ZHanG nai-feng

    2015-01-01

    A comparative slaughter trial was conducted to determine the net mineral requirements for maintenance and growth of Dorper crossbred female lambs raised from 20 to 35 kg of body weight (BW). Thirty-five Dorper×thin-tailed Han crossbred female lambs of (20.3±1.14) kg BW were used: 7 lambs were randomly chosen and slaughtered at the beginning of the experiment as the baseline group for measuring the initial body composition; another 7 lambs were randomly chosen and offered a pelleted mixed diet ad libitum and slaughtered at (27.0±0.73) kg BW; the remaining 21 lambs were randomly divided into 3 groups of 7 animals each and subjected to the same diet either ad libitum or at 70 or 40% of ad libitum intake. The 21 lambs were fed in 7 slaughter groups, with each group consisting of one lamb from each treatment (ad libitum, 70 or 40% of ad libitum intake). The 3 groups were slaughtered when the sheep fed ad libitum attained (33.8±0.52) kg of BW. The body composition of five minerals (Ca, P, Na, K, and Mg) was determined. The net mineral requirements for maintenance were 35.01, 25.18, 9.30, 31.35, and 2.03 mg kg–1 empty BW (EBW) for Ca, P, Na, K, and Mg, respectively, and the net growth requirement per kg of EBW gain ranged from 9.73 to 8.87 g of Ca, 5.83 to 5.27 g of P, 1.73 to 1.63 g of Na, 3.73 to 4.08 g of K, and 0.26 to 0.25 g of Mg for Dorper crossbred lambs in China, respectively. The estimates of mineral requirements with Dorper crossbred lambs in the current study were not consistent with the recommendations from previous studies.

  13. Risk factors for sebaceous gland diseases and their relationship to gastrointestinal dysfunction in Han adolescents.

    Science.gov (United States)

    Zhang, Hong; Liao, Wanqing; Chao, Woon; Chen, Qiaoling; Zeng, Hanxiang; Wu, Chipeng; Wu, Shaoxi; Ho, Hon In

    2008-09-01

    Sebaceous gland diseases are a group of common dermatological diseases with multiple causes. To date, a systematic report of the risk factors for sebaceous gland diseases in adolescents has not been published. The aim of this study was to assess the prevalence and risk factors for certain sebaceous gland diseases (seborrhea, seborrheic dermatitis, acne, androgenetic alopecia and rosacea) and their relationship to gastrointestinal dysfunction in adolescents. From August-October, 2002-2005, a questionnaire survey was carried out to obtain epidemiological data about sebaceous gland diseases. Using random cluster sampling, 13 215 Han adolescents aged 12-20 years were recruited from four countries or districts (Macau; Guangzhou, China; Malaysia; and Indonesia). The statistical software SPSS ver. 13.0 was used to analyze the data. The prevalence of seborrhea, seborrheic dermatitis, acne, androgenetic alopecia and rosacea was 28.27%, 10.17%, 51.03%, 1.65% and 0.97%, respectively. Based on multivariate logistic regression analysis, the risk factors for sebaceous gland diseases included: age; duration of local residency; halitosis; gastric reflux; abdominal bloating; constipation; sweet food; spicy food; family history of acne; late night sleeping on a daily basis; excessive axillary, body and facial hair; excessive periareolar hair; and anxiety. There was a statistically significant difference in the prevalence of gastrointestinal symptoms (halitosis; gastric reflux; abdominal bloating; constipation) between patients with and without sebaceous gland diseases (chi(2) = 150.743; P = 0.000). Gastrointestinal dysfunction is an important risk factor for diseases of the sebaceous glands and is correlated with their occurrence and development. PMID:18837699

  14. Association of TBX5 gene polymorphism with ventricular septal defect in the Chinese Han population

    Institute of Scientific and Technical Information of China (English)

    LIU Cai-xia; SHEN A-dong; LI Xiao-feng; JIAO Wei-wei; BAI Song; YUAN Feng; GUAN Xiao-lei; ZHANG Xin-gen; ZHANG Gui-rong; LI Zhong-zhi

    2009-01-01

    Background Congenital heart disease is a diverse group of diseases determined by genetic and environmental factors. Considerable research has been done on genes associated with development of the heart. A recent focus is the role of transcription factor TBX5 in the development of atria, left ventricle and conduction system. As part of a larger study, high density, single nucleotide polymorphism (SNP) scanning was used to explore the relationship between TBX5 gene polymorphism and susceptibility to ventricular septal defect not associated with forelimb malformation in the Chinese Han population. Methods One hundred and ninety two paediatric patients with congenital ventricular septal defect and 192 matched healthy control subjects were studied. The haplotype reconstructions were calculated by PHASE2.0 software. Haploview software was used to 15erform linkage disequilibrium assessment and defining of haplotype blocks. The algorithm used for defining of blocks was the confidence interval method. Results The TBX5 gene region can be divided into 3 haplotype blocks of 27, 15 and 2 SNPs. Strong linkage disequilibrium exists within each block. SNP rs11067075 within the TBX5 gene had significant correlation with ventricular septal defect (P=0.0037) by single marker association analysis. In addition, a 20 kb haplotype composed of 27 SNPs correlated with ventricular septal defect (P=0.05, multiple loci regression analyses based on reconstructed haplotype blocks). Conclusions TBX5 is associated with the occurrence of ventricular septal defect and may be a predisposing gene to congenital heart disease in Hart Chinese. This finding has set a direction for further genetic and functional studies.

  15. NEDD4 single nucleotide polymorphism rs2271289 is associated with keloids in Chinese Han population.

    Science.gov (United States)

    Zhao, Ying; Liu, Sheng-Li; Xie, Jian; Ding, Mao-Qian; Lu, Meng-Zhu; Zhang, Lan-Fang; Yao, Xiu-Hua; Hu, Bai; Lu, Wen-Sheng; Zheng, Xiao-Dong

    2016-01-01

    Keloids are abnormally raised fibroproliferative lesions that usually occur following cutaneous traumas. Recently, a large-scale genome-wide association study (GWAS) has identified multiple single nucleotide polymorphisms (SNPs) in three genetic loci that are associated with keloids in Japanese population. Subsequently, two reported loci 1q41 (rs873549 and rs1442440) and 15q21.3 (rs2271289) for keloids were confirmed in selected Chinese population. The association of these SNPs with clinical features of keloids, has not yet been studied. To explore the role of these SNPs in the pathogenesis of keloids, we performed a case-controlled study in another independent Chinese Han population to analyze the correlation between 4 SNPs (rs873549, rs2118610, rs1511412, rs2271289) and keloids phenotypes. 309 keloids patients and 1080 control subjects were included. The results showed that, in the dominant mode of inheritance, the minor allele T of SNP rs2271289 had significantly higher odd ratios (ORs) in the severe keloid group compared with both the controls and the mild keloid group. The ORs were maintained after Bonferroni's correction (OR: 4.09, 95% CI: 1.78-9.37, P-value 3.25E-04). The ratio of the severe: mild OR for rs2271289 (dominant model) is (4.73/1.84=2.57). Similar associations in SNP rs2271289 were seen for groups with no family history and multiplesite compared with the control groups. No associations between keloid number, family history or severity relative to the controls were observed for the other three SNPs. Our data support that rs2271289 is strongly associated with severe keloids and might contribute to the complexity of clinical features of keloids. PMID:27158346

  16. Polymorphisms of renin-angiotensin-aldosterone system gene in chinese han patients with nonfamilial atrial fibrillation.

    Directory of Open Access Journals (Sweden)

    Li-Qun Zhao

    Full Text Available Atrial fibrillation(AF is the most common arrhythmia in the adult population. The activated renin-angiotensin-aldosterone system (RAS has been reported to play an important role in the pathogenesis of atrial fibrillation. The aim of this study was to investigate the association between nonfamilial AF and polymorphisms in RAS gene.A total of 931 patients with nonfamilial AF, 663 non-AF heart disease patients and 727 healthy subjects were selected. 10 tagSNPs (tSNPs (ACE gene rs8066114, AGT gene rs7539020, rs3789678, rs2478544, rs11568023, rs2478523, rs4762, rs699 and CYP11B2 rs3802230, rs3097 were chosen and genotyped in our study. Single-locus analysis and haplotype analysis were used in this study.In single-locus analysis, we found rs11568023 and rs3789678 in AGT gene were associated with nonfamilial AF in Chinese Han population. AF risk was associated with rs3789678 between the AF group and control groups. Under dominant model, the significant AF risk was observed in rs3789678 between the AF group and non AF heart control group; And the protective effect was found in rs11568023, compared with the non-AF heart disease control group. In multilocus haplotype analysis, the association between frequencies of the haplotypes and AF risk was showed in AGT gene (rs7539020-rs3789678, compared 'TT' haplotype with the common 'TC' haplotype, adjusted for age, gender, LVEF, LVEDD, LAD and frequency of hypertension and diabetes. The diplotype with 'TC', carrying rs3789678-C-allele, was associated with reduced risk of AF between the AF group and the healthy control group. The diplotype with 'TT' haplotype in the same block, carrying rs3789678-T-allele, was associated with increased risk of AF.Via a large-scale case-control study, we found that rs3789678 site was potential susceptible locus of AF whereas rs11568023 was protective factor.

  17. Establishment of risk model for pancreatic cancer in Chinese Han population

    Institute of Scientific and Technical Information of China (English)

    Xing-Hua Lu; Li Wang; Hui Li; Jia-Ming Qian; Rui-Xue Deng; Lu Zhou

    2006-01-01

    AIM: To investigate risk factors for pancreatic cancer and establish a risk model for Han population.METHODS: This population-based case-control study was carried out from January 2002 to April 2004. One hundred and nineteen pancreatic cancer patients and 238 healthy people completed the questionnaire which was used for risk factor analysis. Logistic regression analysis was used to calculate odds ratio (ORs), 95%confidence intervals (Cis) and β value, which were further used to establish the risk model.RESULTS: According to the study, people who have smoked more than 17 pack-years had a higher risk to develop pancreatic cancer compared to non-smokers or light smokers (not more than 17 pack-years) (OR 1.98;95% CI 1.11-3.49, P=0.017). More importantly, heavy smokers in men had increased risk for developing pancreatic cancer (OR 2.11; 95%CI 1.18-3.78, P=0.012)than women. Heavy alcohol drinkers (>20 cup-years)had increased risk for pancreatic cancer (OR 3.68;95%CI 1.60-8.44). Daily diet with high meat intak was also linked to pancreatic cancer. Moreover, 18.5% of the pancreatic cancer patients had diabetes mellitus compared to the control group of 5.8% (P= 0.0003). Typical symptoms of pancreatic cancer were anorexia, upper abdominal pain, bloating, jaundice and weight loss. Each risk factor was assigned a value to represent its impor tance associated with pancreatic cancer. Subsequently by adding all the points together, a risk scoring model was established with a value higher than 45 as being at risk to develop pancreatic cancer.CONCLUSION: Smoking, drinking, high meat diet and diabetes are major risk factors for pancreatic cancer. A risk model for pancreatic cancer in Chinese Hah population has been established with an 88.9% sensitivity and a 97.6% specificity.

  18. The effect of geographical indices on left ventricular structure in healthy Han Chinese population

    Science.gov (United States)

    Cen, Minyi; Ge, Miao; Liu, Yonglin; Wang, Congxia; Yang, Shaofang

    2016-07-01

    The left ventricular posterior wall thickness (LVPWT) and interventricular septum thickness (IVST) are generally regarded as the functional parts of the left ventricular (LV) structure. This paper aims to examine the effects of geographical indices on healthy Han adults' LV structural indices and to offer a scientific basis for developing a unified standard for the reference values of adults' LV structural indices in China. Fifteen terrain, climate, and soil indices were examined as geographical explanatory variables. Statistical analysis was performed using correlation analysis. Moreover, a back propagation neural network (BPNN) and a support vector regression (SVR) were applied to developing models to predict the values of two indices. After the prediction models were built, distribution maps were produced. The results show that LV structural indices are characteristically associated with latitude, longitude, altitude, average temperature, average wind velocity, topsoil sand fraction, topsoil silt fraction, topsoil organic carbon, and topsoil sodicity. The model test analyses show the BPNN model possesses better simulative and predictive ability in comparison with the SVR model. The distribution maps of the LV structural indices show that, in China, the values are higher in the west and lower in the east. These results demonstrate that the reference values of the adults' LV structural indices will be different affected by different geographical environment. The reference values of LV structural indices in one region can be calculated by setting up a BPNN, which showed better applicability in this study. The distribution of the reference values of the LV structural indices can be seen clearly on the geographical distribution map.

  19. High resolution human leukocyte antigen class I allele frequencies and HIV-1 infection associations in Chinese Han and Uyghur cohorts.

    Directory of Open Access Journals (Sweden)

    Yanhou Liu

    Full Text Available BACKGROUND: Host immunogenetic factors such as HLA class I polymorphism are important to HIV-1 infection risk and AIDS progression. Previous studies using high-resolution HLA class I profile data of Chinese populations appeared insufficient to provide information for HIV-1 vaccine development and clinical trial design. Here we reported HLA class I association with HIV-1 susceptibility in a Chinese Han and a Chinese Uyghur cohort. METHODOLOGY/PRINCIPAL FINDINGS: Our cohort included 327 Han and 161 Uyghur ethnic individuals. Each cohort included HIV-1 seropositive and HIV-1 seronegative subjects. Four-digit HLA class I typing was performed by sequencing-based typing and high-resolution PCR-sequence specific primer. We compared the HLA class I allele and inferred haplotype frequencies between HIV-1 seropositive and seronegative groups. A neighbor-joining tree between our cohorts and other populations was constructed based on allele frequencies of HLA-A and HLA-B loci. We identified 58 HLA-A, 75 HLA-B, and 32 HLA-Cw distinct alleles from our cohort and no novel alleles. The frequency of HLA-B*5201 and A*0301 was significantly higher in the Han HIV-1 negative group. The frequency of HLA-B*5101 was significantly higher in the Uyghur HIV-1 negative group. We observed statistically significant increases in expectation-maximization (EM algorithm predicted haplotype frequencies of HLA-A*0201-B*5101 in the Uyghur HIV-1 negative group, and of Cw*0304-B*4001 in the Han HIV-1 negative group. The B62s supertype frequency was found to be significantly higher in the Han HIV-1 negative group than in the Han HIV-1 positive group. CONCLUSIONS: At the four-digit level, several HLA class I alleles and haplotypes were associated with lower HIV-1 susceptibility. Homogeneity of HLA class I and Bw4/Bw6 heterozygosity were not associated with HIV-1 susceptibility in our cohort. These observations contribute to the Chinese HLA database and could prove useful in the

  20. Hans Lindquist, Corpus Linguistics and the Description of English (Edinburgh University Press, 2009): a Detailed EvaluationIn Corpus Linguistics and the Description of English Hans Lindquist offers another introductory book to corpus linguistics, but aims

    OpenAIRE

    Marlies Gabriele Prinzl

    2010-01-01

    In Corpus Linguistics and the Description of English Hans Lindquist offers another introductory book to corpus linguistics, but aims it specifically at ‘university students of English at intermediate to advanced levels who have a certain background in grammar and linguistics, but who have not had the opportunity to use computer corpora to any great extent’ (Lindquist 2009, xvi). He proposes that the book, especially certain sections of it, may also be of interest to students of literature. Co...

  1. 汉赋主题与汉代«诗经»学%On the Influence of the Study of the Book of Songs in Han Dynasty on the Motifs of Han Prosodies

    Institute of Scientific and Technical Information of China (English)

    金前文

    2013-01-01

    There are many characteristics such as elaborating the monarch′s moralities,praising the gracious monarch and admonishing the monarch for his misconduct through gentle words etc. in the themes of Han Prosodies.These characteristics are stamped with the brand of the study of the Book of Songs in Han Dynasty obviously,manifested the connection with the study of the Book of Songs in Han Dynasty,and affected by the study of the Book of Songs.%汉赋在主题表现上,以“君”为中心,阐述了君德,褒扬了合德之君,对君的失德进行了谏,谏时又极为委婉,采用了“讽谏”的方式。这些特点,都明显地打上了汉代«诗»学的烙印,体现着与汉代«诗经»学的深切关联,是汉代«诗经»学影响的结果。

  2. [Genetic polymorphism of FIBRA,DHFRP2 and ACTBP2 and their forensic application in Yunnan Han population].

    Science.gov (United States)

    Jing, Qiang; Nie, Sheng-Jie

    2002-09-01

    To investigate the genetic polymorphism of FIBRA,DHFRP2 and ACTBP2 in Yunnan Han population as well as their application in forensic science, EDTA-blood specimens were collected from 200 healthy individuals. The DNA were extracted either by the Chloro form, phenol method or by the Chelex-100 method. The PCR products were analyzed by PAG vertical electrophoresis,following by silver staining. All gene frequencies, discrimination power (DP), exclusion of paternity probability (EPP), heterozygosity (H),polymorphisms information content (PIC),matching probability (PM) as well as the Hardy-Weinberg test were calculated. The obtained data are beneficial in the understanding of population genetics of the three STR loci in Yunnan Han population and the results suggest that these loci are valuable genetic markers for paternity testing and personal identification in forensic science practice. PMID:16135442

  3. A study on the formation of fouling in a heat exchanging system for Han-river water as cooling water

    International Nuclear Information System (INIS)

    Scale is formed when hard water is heated or cooled in heat transfer equipments such as heat exchangers, condensers, evaporators, cooling towers, boilers, and pipe walls. When scale deposits in a heat exchanger surface, it is traditionally called fouling. The objective of the present study is to investigate the formation of fouling in a heat exchanging system. A lab-scale heat exchanging system is built-up to observe and measure the formation of fouling experimentally. Water analyses are conducted to obtain the properties of Han river water. In the present study a microscopic observation is conducted to visualize the process of scale formation. Hardness of Han-river water is higher than that of tap water in Seoul

  4. Distribution Characteristics and Linkage Disequilibrium of TIM4 Promoter Polymorphisms in Asthma Patients of Chinese Han Population

    Institute of Scientific and Technical Information of China (English)

    Pengcheng CAI; Qiwen WU; Lin WANG; Juan XIONG; Fenghua CHEN; Lihua HU

    2008-01-01

    To investigate the distribution characteristics and linkage disequilibrium of T cell immunoglobulin domain and mucin domain protein 4 (TIM4) promoter polymorphisms in asthma patients of Chinese Han population, the promoter region of TIM4 was re-sequenced by PCR-sequencing,and linkage disequilibrium was analyzed by SHEsis software. Four single nucleotide polymorphisms (SNPs) in the promoter region of TIM4 were detected, including two new SNPs (at positions-1609, -153) and two reported SNPs (rs6874202, rs6882076). The frequency distribution of rs6882076 was different among different races (P<0.05). In addition, linkage disequilibrium among the SNPs of the promoter region of TIM4 was found and GGTG was the predominant haplotype.There were four SNPs in the promoter region of TIM4 in asthma patients of Chinese Han population,which were in linkage disequilibrium.

  5. HANS FREUDENTHAL, un matemático en Didáctica y teoría curricular

    OpenAIRE

    Gravemeijer, K.P.E.; Terwel, J.

    2000-01-01

    Se describen las principales ideas del trabajo de Hans Freudenthal (1905-1990), el matemático y educador matemático holandés, relacionadas con teoría curricular y didáctica. Se explora el credo educacional de Freudenthal: “la matemática es una actividad humana”. Desde este punto de partida pedagógico, el criticismo de la investigación educativa y las teorías de la educación han sido exploradas y desencarnadas. La aproximación de Freudenthal a la educación matemática, al desarrollo de la inves...

  6. 四川郫县古城乡汉墓%Han Period Tombs at Gucheng Township in Pixian County, Sichuan

    Institute of Scientific and Technical Information of China (English)

    成都市文物考古研究所; 郫县博物馆

    2004-01-01

    In 1997-1998, excavation revealed 14 tombs (12 earthen-pit and two brick-chambered) at Gucheng and Xinlu villages in Gucheng Township about 8 km north of the seat of Pixian County.They yielded rich funeral objects, including bronze, pottery, iron and bone articles. The pottery forms an overwhelming majority. It consists mainly of clay ware, and sandy one occurs in a small amount.There are gray and some brown products with plain surface in most cases. They belong to the jar, bo bowl, basin, fu cauldron, zeng steamer, ding tripod, models of well and kitchen range, etc. The earthen-pit tombs should be dated to the Western Han period, while the brick-chambered to the Eastern Han.

  7. Síndrome de Rett: 50 años de historia de un trastorno aun no bien conocido Rett syndrome: 50 years' history of a still not well known condition

    Directory of Open Access Journals (Sweden)

    Jaime Campos-Castello

    2007-01-01

    Full Text Available Desde que fue descrito por primera vez por Andreas Rett hace 50 años, el síndrome de Rett (SR ha sido objeto de muchas investigaciones, sin embargo continúa siendo un trastorno aún no bien conocido. Presentamos nuestra propia experiencia y una revisión de la literatura sobre el SR. Se trata de un trastorno del neurodesarrollo, dominante ligado a X, que afecta casi siempre a mujeres, la mayoría de los casos de forma esporádica. El diagnóstico de SR debe hacerse en base a la observación clínica. Las principales características son la aparición de un retraso mental, cambios conductuales, estereotipias, pérdida del lenguaje y, sobre todo, del uso propositivo de las manos, aparición de una apraxia de la marcha, presencia de alteraciones de la respiración y, frecuentemente, crisis epilépticas. Los criterios diagnósticos consensuados internacionalmente son aquí revisados. El SR se debe en la mayoría de casos a mutaciones del gen MECP2, si bien una proporción de casos atípicos puede estar causada por mutaciones de CDKL5, particularmente la variante con epilepsia precoz. Sin embargo, los mecanismos patogénicos moleculares no son bien conocidos, así como la relación entre las mutaciones de MECP2 y otros trastornos del desarrollo. Revisamos también los hallazgos de neuroimagen, neuropatológicos y neurobioquímicos descritos en el SR. Respecto al tratamiento, aparte del sintomático, no hay ninguno que se haya mostrado eficaz. Un trabajo reciente abre perspectivas terapéuticas futuras al haber demostrado mediante un modelo animal de ratón la reversión de los síntomas neurológicos mediante la activación de la expresión de MeCP2.Since it was first described by Andrea Rett 50 years ago, Rett syndrome (RS has been the subject of further investigations, nonetheless it continues to be a not well known condition. Our own experience and an updated literature review on RS is presented. RS is a severe dominant X chromosome

  8. Valoración de bienes rústicos de utilidad pública: La expropiación forzosa por las obras del AVE en la provincia de León

    Directory of Open Access Journals (Sweden)

    María del Pilar Gutiérrez Flórez

    2010-06-01

    Full Text Available Con motivo de la expropiación forzosa de fincas en la provincia de León debido a las obras del Tren de Alta Velocidad, AVE, los propietarios de ochenta y dos fincas de los Ayuntamientos de Villanueva de las Manzanas, Santas Martas y Vega de Infanzones, solicitaron un estudio de valoración alternativo de las mismas para presentarlo, en forma de alegaciones individuales, al Jurado Provincial de Expropiación Forzosa de León, tal y como es su derecho, según la Ley de Expropiación Forzosa, LEF, por su desacuerdo con la oferta de la Entidad Expropiante.En este artículo se presenta el método, se justifican los criterios de valoración, se presentan y analizan los resultados obtenidos y se elaboran las conclusiones a partir de los informes individuales, tras el reconocimiento de los terrenos afectados y su entorno, en base a datos obtenidos bien sea de la propia entidad expropiante bien de la normativa autonómica en vigor en el momento de la expropiación, o bien de la Ley del Suelo 8/2007 en lo referente a la toma de decisiones para el planteamiento de las hipótesis de partida del estudio.Por último, se justifican la tasa del tipo de interés utilizado para la Capitalización de las rentas, en base a normativa vigente o estudios oficiales, y el coeficiente multiplicador del valor de las mismas, según los modelos territoriales de situación respecto a un núcleo urbano, ambos parámetros necesarios para determinar el valor de las parcelas.On the occasion of the necessary expropriation of lands in the province of León due to the works of the High-speed train, AVE (HIGH SPEED TRAIN, the owners of eighty two plots of Villanueva de las Manzanas, Santas Martas and Vega de Infanzones, requested an choice study of valuation of the same ones it to present, in the individual allegations, to the Provincial Juror of Necessary Expropriation of León, as it is your choice, according to the Spanish Law of Necessary Expropriation, LEF, for your

  9. Association between Polymorphisms in Interleukins 4 and 13 Genes and Chronic Periodontitis in a Han Chinese Population

    OpenAIRE

    Dong Chen; Tian-liang Zhang; Xia Wang

    2016-01-01

    Chronic periodontitis (CP) is one of the most common chronic inflammatory diseases and cytokines play a pivotal role in the regulation of immune response. Interleukin-4 (IL-4) and interleukin-13 (IL-13) are anti-inflammatory cytokines and several polymorphisms of them have been proved involved in periodontal disease. This study aimed to evaluate whether three single nucleotide polymorphisms (SNPs), rs2070874 and rs2243248 from IL4 and rs1800925 from IL13, are associated with CP in a Han Chine...

  10. Correlation between single nucleotide polymorphism of FCRL-3 gene and Graves’ disease in Han population of northern Anhui province, China

    OpenAIRE

    Jin, Guo-Xi; Zhou, Yu-Ye; Yu, Lei; Bi, Ya-Xin

    2015-01-01

    Objective: The frequency distribution of A/G genotype at position-169 in promoter of FCRL3 gene (Fc receptor-like 3) was identified in Han population of northern Anhui Province. The correlation between single nucleotide polymorphism (SNP) at this site and genetic susceptibility of Graves disease (GD) was discussed. How the genotype at this position correlated to age, gender, severity of goiter, presence or absence of exophthalmos, levels of thyrotrophin receptor antibody (TRab), thyroid perox...

  11. Association of HLA-B27 and ERAP1 with ankylosing spondylitis susceptibility in Beijing Han Chinese.

    Science.gov (United States)

    Zhang, Z; Dai, D; Yu, K; Yuan, F; Jin, J; Ding, L; Hao, Y; Liang, F; Liu, N; Zhao, X; Long, J; Xi, Y; Sun, Y-Y

    2014-05-01

    This study investigated the genetic polymorphisms of HLA-B27, together with polymorphisms on endoplasmic reticulum aminopeptidase 1 (ERAP1), and susceptibility for ankylosing spondylitis (AS) in the Beijing Han population. A case-control study was carried out for 602 AS patient samples and 619 matched controls of Han Chinese. HLA-B27 genotyping was performed by polymerase chain reaction-sequence specific primers (PCR-SSP), and four ERAP1 SNPs (rs27037, rs27980, rs27582, and rs27434) were selected and genotyped on the Sequenom iPlex platform (Sequenom, San Diego, CA). Association analysis was performed using the likelihood ratio χ(2) test. This study identified four HLA-B27 alleles in Beijing Han AS patients, B*27:02, B*27:04, B*27:05, and B*27:07, of which B*27:05 was the most significant geographical different subtype among AS patients in Chinese. Our results confirmed that HLA-B27 was strongly associated with AS (P=1.9 × 10(-150) ), and the most strongly associated alleles were B*27:04, B*27:05, and B*27:02. Our study also confirmed a weak association between ERAP1 (rs27434) and AS. We also observed that for HLA-B*27:02 and HLA-B*27:04 positive AS patients, rs27434 and rs27582 were associated with AS. In contrast, for HLA-B27-negative and HLA-B*27:05-positive AS patients, this association was not observed. This is the first study to show that both B27 and ERAP1 are AS genetic susceptibility genes in Beijing Han. Interactions between ERAP1 and HLA-B*27:02 and B*27:04 may play an important role in the AS pathogenesis. PMID:24666027

  12. Identification of Novel Susceptibility Loci for Kawasaki Disease in a Han Chinese Population by a Genome-Wide Association Study

    OpenAIRE

    Tsai, Fuu-Jen; Lee, Yi-Ching; Chang, Jeng-Sheng; Huang, Li-Min; Huang, Fu-Yuan; Chiu, Nan-Chang; Chen, Ming-Ren; CHI, Hsin; Lee, Yann-Jinn; Chang, Li-Ching; Liu, Yi-Min; Wang, Hsiang-Hua; Chen, Chien-Hsiun; Chen, Yuan-Tsong; Wu, Jer-Yuarn

    2011-01-01

    Kawasaki disease (KD) is an acute systemic vasculitis syndrome that primarily affects infants and young children. Its etiology is unknown; however, epidemiological findings suggest that genetic predisposition underlies disease susceptibility. Taiwan has the third-highest incidence of KD in the world, after Japan and Korea. To investigate novel mechanisms that might predispose individuals to KD, we conducted a genome-wide association study (GWAS) in 250 KD patients and 446 controls in a Han Ch...

  13. A neuropeptide Y variant (rs16139 associated with major depressive disorder in replicate samples from Chinese Han population.

    Directory of Open Access Journals (Sweden)

    Yongjun Wang

    Full Text Available OBJECTIVE: This study aimed to investigate the single nucleotide polymorphisms (SNPs of neuropeptide Y (NPY and major depressive disorder (MDD in Chinese Han population. DESIGN: Prospective and randomized studies were carried out. PATIENTS: A total of 700 patients (324 male and 376 female; mean age = 40±14.9 years with depression who met the diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV and 673 healthy controls (313 male and 360 female; mean age = 41.9±17.2 years were used to investigate the relationship between SNPs of NPY and the pathogenesis of MDD. A total of 417 patients (195 male and 202 female; mean age = 36±14.2 years diagnosed with MDD and 314 healthy controls (153 male and 161 female; mean age = 37.9±14.2 years from Chinese Han population were used to verify the relationship between SNPs of NPY and the pathogenesis of MDD. INTERVENTION AND OUTCOME: Ligase detection reactions were performed to detect the SNP sites of NPY. A series of statistical methods was carried out to investigate the correlation between the NPY gene SNP and MDD. RESULTS: Statistical analysis showed a significant correlation between the SNP sites rs16139 in NPY and the morbidity of depression. Patients with MDD have a lower frequency of A-allele in rs16139 in replicate samples from Chinese Han population. However, the frequency varied between male and female patients. CONCLUSION: The gene polymorphism loci rs16139 was closely related to MDD in Chinese Han population.

  14. El autismo 70 años después de Leo Kanner y Hans Asperger

    OpenAIRE

    Artigas-Pallarès, Josep; Paula, Isabel

    2012-01-01

    A partir de las aportaciones de Leo Kanner (1943) y Hans Asperger (1944), el autismo ha sido foco de intenso debate, no sólo sobre aspectos fenomenológicos, etiológicos y terapéuticos;sino también sobre su propia naturaleza. La presente revisión pretende situar el autismo como un concepto dinámico sometido a interpretaciones no solo diversas, sino radicalmente enfrentadas.

  15. Positive Association Between Type 2 Diabetes Risk Alleles Near CDKAL1 and Reduced Birthweight in Chinese Han Individuals

    Directory of Open Access Journals (Sweden)

    Xiao-Fang Sun

    2015-01-01

    Conclusions: This study identified the association between type 2 diabetes risk variants in CDKAL1 and birthweight in Chinese Han individuals, and the carrier of risk allele within SRR had the trend of reduced birthweight. This demonstrates that there is a clear overlap between the genetics of type 2 diabetes and fetal growth, which proposes that lower birth weight and type 2 diabetes may be two phenotypes of one genotype.

  16. Positive Association Between Type 2 Diabetes Risk Alleles Near CDKAL1 and Reduced Birthweight in Chinese Han Individuals

    OpenAIRE

    Xiao-Fang Sun; Xin-Hua Xiao; Zhen-Xin Zhang; Ying Liu; Tao Xu; Xi-Lin Zhu; Yun Zhang; Xiao-Pan Wu; Wen-Hui Li; Hua-Bing Zhang; Miao Yu

    2015-01-01

    Background: Fetal insulin hypothesis was proposed that the association between low birth weight and type 2 diabetes is principally genetically mediated. The aim of this study was to investigate whether common variants in genes CDKAL1, HHEX, ADCY5, SRR, PTPRD that predisposed to type 2 diabetes were also associated with reduced birthweight in Chinese Han population. Methods: Twelve single nucleotide polymorphisms (rs7756992/rs10946398 in CDKAL1, rs1111875 in HHEX, rs391300 in SRR, rs175844...

  17. The relationship between polymorphisms in the promoter region of Tim-3 and unexplained recurrent spontaneous abortion in Han Chinese women

    OpenAIRE

    Shen, Yang; Wang, Chen; Hong, Dun; Zeng, Baojin; Fang, Congcheng; Yuan, Chiting; Fan, Lilong; Lv, Haiyan; Zhu, Min

    2013-01-01

    Background Recurrent spontaneous abortion (RSA) refers to 2 or more consecutive pregnancy losses, and RSA with unknown causes is called unexplained recurrent spontaneous abortion (URSA). Tim-3, a subtype of the T-cell immunoglobulin domain and mucin domain (Tim) protein family, might be an important regulatory molecule that plays a pivotal role in URSA, which might be triggered mostly by Th1/Th2 immune deviation. To understand the etiology and pathogenesis of URSA in Han Chinese women, we inv...

  18. C-reactive protein polymorphisms and genetic susceptibility to ischemic stroke and hemorrhagic stroke in the Chinese Han population

    OpenAIRE

    Wang, Qi; Ding, Hu; Tang, Jia-rong; Zhang, Lan; Xu, Yu-jun; Yan, Jiang-tao; Wang, Wei; Hui, Ru-tai; Wang, Cong-Yi; Wang, Dao-wen

    2009-01-01

    Aim: The inflammatory marker C-reactive protein (CRP) has been strongly correlated with the risk of cardiovascular disease. Some single-nucleotide polymorphisms (SNPs) have been reported to be associated with serum CRP levels. In this study, we assessed the genetic association between SNPs within the CRP gene and ischemic and hemorrhagic stroke in the Han Chinese population. Methods: This study comprises 564 ischemic stroke patients, 220 hemorrhagic stroke patients and 564 controls from the e...

  19. Meta-analysis of association studies between five candidate genes and type 2 diabetes in Chinese Han population.

    Science.gov (United States)

    Jing, Chen; Xueyao, Han; Linong, Ji

    2012-10-01

    The multiple small-scale association studies of candidate genes for type 2 diabetes mellitus in the Chinese Han population have shown inconsistent results. Here, we performed a meta-analysis to evaluate the contribution of five candidate genes to the pathogenesis of type 2 diabetes in the Chinese Han population. We searched for relevant published papers and used STATA v.11.0 to perform a meta-analysis on six single-nucleotide polymorphisms in five genes-ADIPOQ-rs2241766 (SNP45) and -rs1501299 (SNP276), ADRB3-rs4994 (Trp64Arg), CAPN10-rs3792267 (SNP43), ENPP1-rs1044498 (K121Q), and PPARGC1A-rs8192678 (Gly482Ser)-in the Chinese Han population under an additive genetic model. The pooled odds ratios (95% confidence intervals and P-values) were 0.71 (0.60-0.83; P ADRB3-rs4994, 0.79 (0.57-1.10; P = 0.163) for CAPN10-rs3792267, 1.41 (1.13-1.76; P = 0.003) for ENPP1-rs1044498, and 1.54 (1.34-1.81; P ADRB3-rs4994, ENPP1-rs1044498, and PPARGC1A-rs8192678 (I² = 0.0, 43.4, and 23.3%, respectively). Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of ENPP1-rs1044498, and the A allele of PPARGC1A-rs8192678 increase the risk of type 2 diabetes in the Chinese Han population. PMID:22391941

  20. Genetic association between CARD9 variants and inflammatory bowel disease was not replicated in a Chinese Han population

    OpenAIRE

    Wang, Zhengting; Fan, Rong; Wang, Lei; Zhou, Jie; Zheng, Sichang; Hu, Shurong; Chen, Mengmeng; Zhang, Tianyu; Lin, Yun; Zhang, Maochen; Zhong, Jie

    2015-01-01

    Objective: In order to investigate whether CARD9 gene is associated with IBD in Chinese Han population, we replicated 2 SNPs of CARD9 which have been reported to be significantly associated with IBD. Methods: Two SNPs were genotyped using polymerase chain reaction with sequence-specific primers in 288 patients (232 CD patients, 56 UC patients) and 274 controls. Results: The frequencies and distributions of alleles and genotypes of the tested SNPs were analyzed, and no significant differences ...

  1. Association between PDCD1, CTLA4, and MECP2 gene polymorphisms and systemic lupus erythematosus in the Chinese Northern Han.

    Science.gov (United States)

    Dong, H R; Li, H S; Wang, S C; Balin, Q M; Chang, P Y

    2015-01-01

    Systemic lupus erythematosus (SLE) is an autoimmune disease that results in chronic inflammation of different organ systems. Several susceptibility loci for SLE have been suggested in different populations, but the nature of the susceptibility genes has yet to be determined. The programmed cell death 1 gene (PDCD1), the cytotoxic T-lymphocyte-associated protein 4 (CTLA4) gene, and the methyl-CpG-binding protein 2 gene (MECP2) are considered to be the candidate genes associated with SLE. We analyzed the role of PDCD1, CTLA4, and MECP2 gene polymorphisms in Han patients suffering from SLE. Using a case-control study, 263 SLE patients and 263 healthy controls were collected from Chinese Northern Han people. Genomic DNA was prepared from peripheral blood leukocytes and the genotyping was performed using a polymerase chain reaction/ligase detection reaction assay. A statistically significant difference was observed in the rs2239464 and rs2075596 polymorphisms of MECP2 between SLE subjects and controls. The GG genotype in rs2239464 and the GG genotype in rs2075596 might protect against SLE. In contrast, no such association was found in the CTLA4 or PDCD1 polymorphisms. The rs2239464 and rs2075596 polymorphisms of MECP2 might play a significant role in the development of SLE in the Northern Han of China. PMID:26782401

  2. 盛行于世的汉代博戏%On the Characteristics of Gambling of Han Dynasty

    Institute of Scientific and Technical Information of China (English)

    龚阔英

    2012-01-01

    汉代的博戏种类多样,主要有博戏、塞戏、弈棋、斗戏等形式。博戏在两汉时期较为盛行,各个阶层广泛参与,上至帝王将相,下至黎民百姓,市井商贾都比较热衷。更为甚者,汉人认为死后可继续享乐,所以墓葬中多备有博具。博戏盛行与当时经济状况、统治阶层导向、制度不完善等因素密切相关。%The Han Dynasty is an important period in the gambling history, various torms ot gambling, the extensive classes, as well as the gambling concept of after death, it becomes the main characteristics of the Han Dynasty gambling, and the main performance of prevalence. Some forms of gambling in the Han Dynasty have a far-reaching impact on later age,it occupies an important position in the history of the gambling.

  3. Haplotype diversity of 17 Y-STR loci in a Chinese Han population sample from Shanxi Province, Northern China.

    Science.gov (United States)

    Bai, Rufeng; Zhang, Zhong; Liang, Quanzeng; Lu, Di; Yuan, Li; Yang, Xue; Shi, Mei sen

    2013-01-01

    The distribution of 17 Y-chromosome STR loci DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y-GATA-H4, DYS437, DYS438, and DYS448 haplotypes was determined in a population sample of 222 unrelated Chinese Han from Shanxi Province, Northern China. A total of 219 haplotypes were observed, and of these, 216 were unique, while 3 were found two times. The overall haplotype diversity was 0.9999 and the discrimination capacity was 0.9865, indicating a high potential for differentiating between male individuals in this population. Comparison analysis via Analysis of Molecular Variance (AMOVA) and construction of MDS plot revealed that Shanxi Han sample clusters with Chinese origin populations and stands far apart of the non-Chinese populations, justifying the establishment of local databases in Shanxi Han population for any future forensic and genetic epidemiology efforts in this region. PMID:23116721

  4. Quality assurance for safety in the radioactive waste management: a quality assurance system in Novi Han radioactive waste repository

    International Nuclear Information System (INIS)

    Novi Han Radioactive Waste Repository (RWR) is still the only place in Bulgaria for storage of low and intermediate level radioactive waste. It is necessary to establish and maintain a Quality Assurance (QA) system to ensure that the RWR can be operated safely with regard to the health and safety of the general public and site personnel. A QA system has to establish the basic requirements for quality assurance in order to enhance nuclear safety by continuously improving the methods employed to achieve quality. It is envisaged that the QA system for the Novi Han RWR will cover the operation and maintenance of the radioactive waste disposal facilities, the radiation protection and monitoring of the site, as well as the scientific and technology development aspects. The functions of the Novi Han RWR presume the availability of an environmental management system. It is appropriate to establish a QA system based on the requirements of the ISO Standards 9001 and 14000, using the recommendations of the IAEA (Quality assurance for safety in NPPs and other nuclear installations, code and safety guides Q1-Q14). (authors)

  5. Analysis of the genotype of diacylglycerol kinase delta single-nucleotide polymorphisms in Parkinson disease in the Han Chinese population

    Directory of Open Access Journals (Sweden)

    Wei Song

    2012-01-01

    Full Text Available Numerous Single-Nucleotide Polymorphisms (SNPs of the Diacylglycerol Kinase Delta (DGKD isoform 1 gene have been associated with Parkinson Disease (PD in the genome-wide association studies of Caucasian population. This association has not been proven in the Han Chinese PD patients. This study included 376 unrelated Han Chinese PD patients from West China and 273 unrelated healthy controls from the same region. Five SNPs (rs2971859, rs1550532, rs2305539, rs2034762, and rs2242102 were genotyped using the Sequenom iPLEX Assay technology. No significant differences were observed in genotype frequencies and in the Minor Allele Frequency (MAF in the five SNPs between PD patients and controls, early-onset PD and controls, late-onset PD and controls, and between early-onset and late-onset PD patients. The present study is the first to report on the lack of association of DGKD SNPs with PD in the Han Chinese population. More related studies involving larger numbers of participants are necessary to confirm the present finding.

  6. High-resolution MRI study of pituitary glands in healthy adult of the Han nationality

    International Nuclear Information System (INIS)

    Objective: To study the morphological characteristics of pituitary glands in healthy adult of the Han nationality on the High-resolution Mill and provide morphological data of pituitary glands for the construction of database for Chinese Standard Brain. Methods: This is a clinical multi-center study. Nine hundred and seventy eight Chinese healthy volunteers (age range=18 to 70 ) recruited from 16 hospitals were divided into 5 groups, i. e., Group A (age range = 18 to 30), B (age range = 31 to 40), C (age range =41 to 50), D (age range = 51 to 60), and E (age range = 61 to 70). All of the volunteers were scanned by MR using T1 weighted three-dimensional magnetization prepared rapid acquisition gradient echo sequence. By Multiplan reconstruction with 3D software, the pituitary gland's volume, size, and inclination of pituitary, stalk were measured and the differences between sexualities and among age groups were compared by analysis of variance using SPSS13.0; those among five age groups were compared pair-wised by Tukey analysis; and the differences between male and female were analyzed by independent t test, and the differences of measurements of typing of pituitary glands were analyzed by Chi-square analysis. Results: (1) Volume of pituitary glands: the mean volume of male and female among 5 age groups were (1142 ± 290), (996 ± 223), (979 ± 178), (971 ± 174), (930 ± 189)and (1247 ± 210), (1199 ± 216), (1108 ± 196), (1059 ± 212), (984 ± 177) mm3 respectively. There were significant differences among the age groups(F=13.811,27.091,P0.05). (4) The typing of pituitary glands in middle sagittal MR images: there were significant differences between each typing (χ2=44.212, 107.518, P<0.01), there was a tendency of pituitary upper border to depressed when age increased. Conclusions: With high- resolution Mill and 3D volumetric analytic software, volume and size of pituitary glands and the angle of inclination of pituitary stalks were accurately measured, and

  7. Genotyping for Kidd, Kell, Duffy, Scianna, and RHCE blood group antigens polymorphisms in Jiangsu Chinese Han

    Institute of Scientific and Technical Information of China (English)

    LIU Zhong; ZHANG Xue-guang; ZENG Rong; CHEN Qing; LI Min; SHI Guang-yao; WEI Peng; HUANG Cheng-yin; TANG Rong-cai; SUN Jun

    2012-01-01

    Background Molecular testing is more precise compared to serology and has been widely used in genotyping blood group antigens.Single nucleotide polymorphisms (SNPs) of blood group antigens can be determined by the polymerase chain reaction with sequence specific priming (PCR-SSP) assay.Commercial high-throughput platforms can be expensive and are not approved in China.The genotype frequencies of Kidd,Kell,Duffy,Scianna,and RhCE blood group antigens in Jiangsu province were unknown.The aim of this study is sought to detect the genotype frequencies of Kidd,Kell,Duffy,Scianna,and RhCE antigens in Jiangsu Chinese Han using molecular methods with laboratory developed tests.Methods DNA was extracted from EDTA-anticoagulated blood samples of 146 voluntary blood donors collected randomly within one month.Standard serologic assay for red blood cell antigens were also performed except the Scianna blood group antigens.PCR-SSP was designed to work under one PCR program to identify the following SNPs:JK1/JK2,KEL 1/KEL2,FYA/FYB,SC1/SC2,C/c and E/e.Results Serologic antigen results were identical to the phenotypes that were predicted from genotyping results.The allele frequencies for Jk*01 and Jk*02 were 0.51 and 0.49,respectively; for Fy*A and Fy*B 0.94 and 0.06; for RHCE*C and RHCE*c 0.68 and 0.32; and for RHCE*E and RHCE*e 0.28 and 0.72.Among 146 blood donors,all were KEL*02/KEL*02 and SC*01/SC*01,indicating allele frequencies for KEL*02 and SC*01 close to 1.00.Conclusions The use of PCR-SSP working under the same condition for testing multiple antigens at the same time is practical.This approach can be effective and cost-efficient for small-scale laboratories and in developing counties.These molecular tests can be also used for identifying rare blood types.

  8. Involvement of tryptophan hydroxylase 2 gene polymorphisms in susceptibility to tic disorder in Chinese Han population

    Directory of Open Access Journals (Sweden)

    Zheng Ping

    2013-01-01

    Full Text Available Abstract Background Tryptophan hydroxylase-2 (TPH2 is a potential candidate gene for screening tic disorder (TD. Methods A case–control study was performed to examine the association between the TPH2 gene and TD. The Sequenom® Mass ARRAY iPLEX GOLD System was used to genotype two single nucleotide polymorphisms (SNPs of the TPH2 gene in 149 TD children and in 125 normal controls. Results For rs4565946, individuals with the TT genotype showed a significantly higher risk of TD than those with TC plus CC genotypes [odds ratio (OR =3.077, 95% confidence interval (CI: 1.273–7.437; P = 0.009], as did male TD children with the TT genotype (OR = 3.228, 95% CI: 1.153–9.040; P = 0.020. The G allele of rs4570625 was significantly more frequent in TD children with higher levels of tic symptoms (Yale Global Tic Severity Scale, YGTSS than those in controls among the male children (OR = 1.684, 95%: 1.097–2.583; P = 0.017]. TD children with severe tic symptoms had significantly higher frequencies of rs4546946 TT genotype than did normal controls in boys (OR = 3.292, 95% CI: 1.139–9.513; P = 0.022. We also found that genotype distributions of both SNPs were different between the Asian and European populations. Conclusions Our results indicated that the TT genotype of rs4565946 is a potential genetic risk factor for TD, and the allele G of rs4570625 might be associated with the severity of tic symptoms in boys. These polymorphisms might be susceptibility loci for TD in the Chinese Han population. Because of the confounding of co-existing attention deficit hyperactivity disorder (ADHD,these findings need to be confirmed by studies in much larger samples.

  9. Research on the Identities of Concubines in the Han Dynasty%汉代后妃面貌考察

    Institute of Scientific and Technical Information of China (English)

    唐会霞

    2012-01-01

    The concubine system is a decadent social system of ancient Chinese society that produce under the concept of thinking that women are inferior to men for thousands of years. The imperial concubines are a particular group. From the origin point of view, many the imperial concubines in Western Han Dynasty were born in lower stratum and those in the Eastern Han Dynasty mostly born in rich and powerful families. The concubines that win emperor's favor or bear prince will be appointed as the empress in West Han Dynasty. In East Dynasty, the concubines that born in rich and powerful families and with nobility nature, will be appointed as the empresses. The impe- rial concubines had mostly higher educational level. The imperial concubines in Western Han Dynasty were good at Singing and dancing and those in the Eastern Han Dynasty master Confucian classics. The imperial concubines become the representative group by the good cultural accomplishment and the outstanding political ability and have higher social status compare the later.%后妃制度是绵延我国古代社会数千年的一种腐朽的社会制度,是男尊女卑观念下的历史产物。汉代后妃是古代后妃中的一个特定群体。从出身来看,西汉后妃出身下层者较多,东汉后妃则大多出自豪门。西汉册封皇后以帝王宠爱与生育皇子为主,东汉则以德为先。两汉后妃大多受教育程度较高。西汉后妃以雅善歌舞为主,东汉后妃以熟读儒经为长。凭借良好的文化素养与杰出的政治才干,两汉后妃成为中国历史上后妃参政的代表性群体。与后世相比,其社会地位相对较高。

  10. Bien s’entourer pour mieux gouverner

    OpenAIRE

    Balouzat-Loubet, Christelle

    2011-01-01

    Le comté d’Artois revient à Mahaut, épouse du comte de Bourgogne Othon IV, en 1302. Veuve quelques mois plus tard, elle se retrouve seule à la tête de la principauté qu’elle gouverne à l’aide d’officiers toujours plus nombreux. Les baillis, le receveur, le trésorier et les autres officiers de l’Hôtel assurent le fonctionnement financier, judiciaire et domestique de la principauté artésienne. Plus proches de Mahaut, ses conseillers prennent une part active à la vie politique du comté. Le servi...

  11. Ciudad, bien y participación

    OpenAIRE

    Riva, F.

    2003-01-01

    The socio-political and metaphysical idea of participation seem to be distant and perhaps contrasting. But the ancient controversy about the names of the good (and the being) —univocal, equivocal, analogous— appears to be both metaphysical and political: having to deal with the multiplicity of the human, the question of unity and plurality of meanings cannot be dissociated from the discussion on the alternative models of human society (egalitarianism, individualism, participation).

  12. ADAM SMITH, UN LIBERALISMO BIEN TEMPERADO

    OpenAIRE

    Roland Pfefferkorn

    2008-01-01

    Gracias a la inmensa fortuna que ha conocido Enquiry into the Nature and Causes of the Wealth of Nations, Adam Smith es considerado como el "padre fundador" de la economía política clásica. Una lectura rápida de la obra ha permitido a veces hacer del célebre economista un pensador simplemente liberal, en una acepción parcial de la palabra. La Riqueza de las naciones merece una lectura cuidadosa. Aunque Smith es conocido principalmente como economista político, no hay que olvidar que fue titul...

  13. Chapitre 6. Le bien en pratique

    OpenAIRE

    Mol, Annemarie

    2013-01-01

    Ce dernier chapitre entremêle les différentes facettes de la logique du choix et de la logique du soin explorées au fil des chapitres précédents. Ce faisant, je me penche sur la question de l’activité morale pour revenir ensuite sur la notion d’“acteur”. Parvenir à articuler ce qui constitue le “patient actif” est en quelque sorte le couronnement de ce livre. En m’appuyant sur le cas du traitement et de la vie avec le diabète, j’ai fait ressortir une version singulière, spécifique et détaillé...

  14. Sobre la promoción y la evaluación de la calidad de la educación superior como bien público y social

    Directory of Open Access Journals (Sweden)

    Rodrigo Arocena Linn

    2011-01-01

    Full Text Available Se considera la evaluación de la educación superior como bien público y social. Dado el creciente peso del conocimiento en las relaciones de poder, el ideal del Movimiento Latinoamericano de la Reforma Universitaria apunta a la centralidad de la democratización del conocimiento. Esta meta orienta el análisis de las tareas de las universidades públicas latinoamericanas en el contexto de la internacionalización de la educación superior. Generalizar el acceso a la educación avanzada y promover el éxito en los estudios aparecen como objetivos prioritarios. La noción de universidad para el desarrollo vertebral el enfoque. Esta noción se conecta con los procesos de innovación y las necesidades sociales, esbozando una estrategia para conectar la enseñanza, la investigación y la extensión con la inclusión social. Una (segunda Reforma Universitaria es necesaria para colaborar en el enfrentamiento a la desigualdad y al subdesarrollo. Impulsar esa colaboración debiera orientar la evaluación de las universidades.

  15. Variants of Interferon Regulatory Factor 5 are Associated with Neither Neuromyelitis Optica Nor Multiple Sclerosis in the Southeastern Han Chinese Population

    Directory of Open Access Journals (Sweden)

    Qi-Bing Liu

    2015-01-01

    Conclusions: Our preliminary study indicates that genetic variants in IRF5 may affect neither NMO nor MS in the Southeastern Han Chinese population. Further studies with a large sample size and diverse ancestry populations are needed to clarify this issue.

  16. Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study.

    Directory of Open Access Journals (Sweden)

    Fuu-Jen Tsai

    Full Text Available Kawasaki disease (KD is an acute systemic vasculitis syndrome that primarily affects infants and young children. Its etiology is unknown; however, epidemiological findings suggest that genetic predisposition underlies disease susceptibility. Taiwan has the third-highest incidence of KD in the world, after Japan and Korea. To investigate novel mechanisms that might predispose individuals to KD, we conducted a genome-wide association study (GWAS in 250 KD patients and 446 controls in a Han Chinese population residing in Taiwan, and further validated our findings in an independent Han Chinese cohort of 208 cases and 366 controls. The most strongly associated single-nucleotide polymorphisms (SNPs detected in the joint analysis corresponded to three novel loci. Among these KD-associated SNPs three were close to the COPB2 (coatomer protein complex beta-2 subunit gene: rs1873668 (p = 9.52×10⁻⁵, rs4243399 (p = 9.93×10⁻⁵, and rs16849083 (p = 9.93×10⁻⁵. We also identified a SNP in the intronic region of the ERAP1 (endoplasmic reticulum amino peptidase 1 gene (rs149481, p(best = 4.61×10⁻⁵. Six SNPs (rs17113284, rs8005468, rs10129255, rs2007467, rs10150241, and rs12590667 clustered in an area containing immunoglobulin heavy chain variable regions genes, with p(best-values between 2.08×10⁻⁵ and 8.93×10⁻⁶, were also identified. This is the first KD GWAS performed in a Han Chinese population. The novel KD candidates we identified have been implicated in T cell receptor signaling, regulation of proinflammatory cytokines, as well as antibody-mediated immune responses. These findings may lead to a better understanding of the underlying molecular pathogenesis of KD.

  17. Surfactant Protein B 1580 Polymorphism Is Associated with Susceptibility to Chronic Obstructive Pulmonary Disease in Chinese Han Population

    Institute of Scientific and Technical Information of China (English)

    胡瑞成; 徐永健; 张珍祥

    2004-01-01

    Summary: Whether surfactant protein B (SP-B)-18A/C and 1580C/T polymorphism were associated with susceptibility to chronic obstructive pulmonary disease (COPD) in Chinese Han population was investigated. After genomic DNA was isolated from blood of COPD smokers and control smokers, the genotypes of SP-B-18A/C and SP-B1580C/T polymorphism loci were determined by polymerase chain reaction restriction fragment length polymorphism analysis (PCR-RFLP) respectively.The results showed that there was significant difference in genotypes distribution frequency of SPB1580C/T polymorphism locus between COPD smokers and control smokers. C→T mutation rate (including TT homozygote and CT heterozygote) in COPD smokers was higher than in control smokers (57.9 % vs 41.7 %, x2 =4.93, P<0.05), whereas there was no significant difference in genotypes distribution frequency of SP-B1580-18A/C locus between COPD smokers and control smokers. The allele frequency (29.1 %) of SP-B1580-18A/C locus is lower than T allele (70.9 %)in Chinese Han Population, and the distribution was different from that in Mexican, in which, the A and T allele frequencies were 85 % and 15 % respectively. It was concluded that SP-B1580 T allele was probably associated with increased susceptibility to COPD in Chinese Han population;The polymorphism of SP-B-18A/C locus maybe varied with race.

  18. Tumor Necrosis Factor-alpha Induced Protein 3 Interacting Protein 1 Gene Polymorphisms and Pustular Psoriasis in Chinese Han Population

    Science.gov (United States)

    Han, Jian-Wen; Wang, Yong; Alateng, Chulu; Li, Hong-Bin; Bai, Yun-Hua; Lyu, Xin-Xiang; Wu, Rina

    2016-01-01

    Background: Psoriasis is a common immune-mediated inflammatory dermatosis. Generalized pustular psoriasis (GPP) is the severe and rare type of psoriasis. The association between tumor necrosis factor-alpha induced protein 3 interacting protein 1 (TNIP1) gene and psoriasis was confirmed in people with multiple ethnicities. This study was to investigate the association between TNIP1 gene polymorphisms and pustular psoriasis in Chinese Han population. Methods: Seventy-three patients with GPP, 67 patients with palmoplantar pustulosis (PPP), and 476 healthy controls were collected from Chinese Han population. Six single nucleotide polymorphisms (SNPs) of the TNIP1 gene, namely rs3805435, rs3792798, rs3792797, rs869976, rs17728338, and rs999011 were genotyped by using polymerase chain reaction-ligase detection reaction. Statistical analyses were performed using the PLINK 1.07 package. Allele frequencies and genotyping frequencies for six SNPs were compared by using Chi-square test, odd ratio (OR) (including 95% confidence interval) were calculated. The haplotype analysis was conducted by Haploview software. Results: The frequencies of alleles of five SNPs were significantly different between the GPP group and the control group (P ≤ 7.22 × 10−3), especially in the GPP patients without psoriasis vulgaris (PsV). In the haplotype analysis, the most significantly different haplotype was H4: ACGAAC, with 13.1% frequency in the GPP group but only 3.4% in the control group (OR = 4.16, P = 4.459 × 10−7). However, no significant difference in the allele frequencies was found between the PPP group and control group for each of the six SNPs (P > 0.05). Conclusions: Polymorphisms in TNIP1 are associated with GPP in Chinese Han population. However, no association with PPP was found. These findings suggest that TNIP1 might be a susceptibility gene for GPP. PMID:27364786

  19. Three slow skeletal muscle troponin genes in small-tailed Han sheep (Ovis aries): molecular cloning, characterization and expression analysis.

    Science.gov (United States)

    Sun, Yan; Wang, Guizhi; Ji, Zhibin; Chao, Tianle; Liu, Zhaohua; Wang, Xiaolong; Liu, Guanqing; Wu, Changhao; Wang, Jianmin

    2016-09-01

    To explore the basic characteristics and expressing profile of the three slow skeletal muscle troponin genes TNNC1 (Troponin C type 1), TNNI1 (troponin I type 1) and TNNT1 (troponin T type 1). Three purebred Dorper sheep and another three purebred small-tailed Han sheep were selected. The sequence of the genes from the small-tailed Han sheep was cloned using rapid amplification of cDNA ends and reverse transcription-polymerase chain reaction; The characteristics of the predicted amino acids sequences were analyzed using bioinformatics analysis software; Gene expression analyses were performed using quantitative reverse transcription PCR. The full-length cDNA sequences of the genes were 707, 898, and 1001 bp, respectively, and were submitted to GenBank under accession numbers KR153938, KT218688 and KT218690. The three predicted proteins were predicted to be hydrophilic, non-secretory proteins and contain several phosphorylation sites. Multiple alignments and phylogenetic tree analyses showed that the predicted proteins were relatively conserved in mammals. The expression results of the three genes in eight tissues of Dorper and small-tailed Han sheep revealed that the three genes had a similar mRNA expression pattern, whereas distinct differences were observed among the eight tissues of the two sheep species. We cloned the full-length cDNA of the three genes, analyzed the amino acid sequences, and determined the expression levels of the genes. These results might play important roles in facilitating the future research of the three genes. PMID:27295221

  20. Association of Apo-E gene polymorphism with biochemical and lipid metabolism parameters in patients with diabetic nephropathy of Hui and Han populations in Gansu Province

    Institute of Scientific and Technical Information of China (English)

    郭茜

    2006-01-01

    Objective To study the association of apolipoprotein (Apo) E gene polymorphism with difference in biochemical metabolism of diabetic nephropathy of Hui and Han populations. Methods ApoE genotype was determined by PCR-RFLP in diabetic patients with or without diabetic nephropathy (DN) and normal peoples in Hui and Han peoples, the related biochemical parameters were simultaneously detected. Results (1) Huis had 3 genotypes, i. e. E2/E3, E3/E3 and E3/E4, and their fre-