Gender bias in the force concept inventory?
Dietz, R. D.; Pearson, R. H.; Semak, M. R.; Willis, C. W.
2012-02-01
Could the well-established fact that males tend to score higher than females on the Force Concept Inventory (FCI) be due to gender bias in the questions? The eventual answer to the question hinges on the definition of bias. We assert that a question is biased only if a factor other than ability (in this case gender) affects the likelihood that a student will answer the question correctly. The statistical technique of differential item functioning allows us to control for ability in our analysis of student performance on each of the thirty FCI questions. This method uses the total score on the FCI as the measure of ability. We conclude that the evidence for gender bias in the FCI questions is marginal at best.
Energy Technology Data Exchange (ETDEWEB)
Makhnovskii, Yurii A. [Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Leninsky Prospect 29, Moscow 119991 (Russian Federation); Berezhkovskii, Alexander M. [Mathematical and Statistical Computing Laboratory, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20819 (United States); Antipov, Anatoly E. [Faculty of Fundamental Physics and Chemical Engineering, Moscow State University, GSP-1, 1-51 Leninskie Gory, Moscow 119991 (Russian Federation); Zitserman, Vladimir Yu. [Joint Institute for High Temperatures, Russian Academy of Sciences, Izhorskaya 13, Bldg. 2, Moscow 125412 (Russian Federation)
2015-11-07
This paper is devoted to particle transport in a tube formed by alternating wide and narrow sections, in the presence of an external biasing force. The focus is on the effective transport coefficients—mobility and diffusivity, as functions of the biasing force and the geometric parameters of the tube. Dependences of the effective mobility and diffusivity on the tube geometric parameters are known in the limiting cases of no bias and strong bias. The approximations used to obtain these results are inapplicable at intermediate values of the biasing force. To bridge the two limits Brownian dynamics simulations were run to determine the transport coefficients at intermediate values of the force. The simulations were performed for a representative set of tube geometries over a wide range of the biasing force. They revealed that there is a range of the narrow section length, where the force dependence of the mobility has a maximum. In contrast, the diffusivity is a monotonically increasing function of the force. A simple formula is proposed, which reduces to the known dependences of the diffusivity on the tube geometric parameters in both limits of zero and strong bias. At intermediate values of the biasing force, the formula catches the diffusivity dependence on the narrow section length, if the radius of these sections is not too small.
The estimation method of GPS instrumental biases
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
A model of estimating the global positioning system (GPS) instrumental biases and the methods to calculate the relative instrumental biases of satellite and receiver are presented. The calculated results of GPS instrumental biases, the relative instrumental biases of satellite and receiver, and total electron content (TEC) are also shown. Finally, the stability of GPS instrumental biases as well as that of satellite and receiver instrumental biases are evaluated, indicating that they are very stable during a period of two months and a half.
Distributed force probe bending model of critical dimension atomic force microscopy bias
Ukraintsev, Vladimir A.; Orji, Ndubuisi G.; Vorburger, Theodore V.; Dixson, Ronald G.; Fu, Joseph; Silver, Rick M.
2013-04-01
Critical dimension atomic force microscopy (CD-AFM) is a widely used reference metrology technique. To characterize modern semiconductor devices, small and flexible probes, often 15 to 20 nm in diameter, are used. Recent studies have reported uncontrolled and significant probe-to-probe bias variation during linewidth and sidewall angle measurements. To understand the source of these variations, tip-sample interactions between high aspect ratio features and small flexible probes, and their influence on measurement bias, should be carefully studied. Using theoretical and experimental procedures, one-dimensional (1-D) and two-dimensional (2-D) models of cylindrical probe bending relevant to carbon nanotube (CNT) AFM probes were developed and tested. An earlier 1-D bending model was refined, and a new 2-D distributed force (DF) model was developed. Contributions from several factors were considered, including: probe misalignment, CNT tip apex diameter variation, probe bending before snapping, and distributed van der Waals-London force. A method for extracting Hamaker probe-surface interaction energy from experimental probe-bending data was developed. Comparison of the new 2-D model with 1-D single point force (SPF) model revealed a difference of about 28% in probe bending. A simple linear relation between biases predicted by the 1-D SPF and 2-D DF models was found. The results suggest that probe bending can be on the order of several nanometers and can partially explain the observed CD-AFM probe-to-probe variation. New 2-D and three-dimensional CD-AFM data analysis software is needed to take full advantage of the new bias correction modeling capabilities.
Self-Biased-SMA Drive PU Microgripper with Force Sensing in Visual Servo
Ren-Jung Chang; Chih-Cheng Shiu; Chih-Yi Cheng
2013-01-01
An innovative design of a polyurethane microgripper system with force sensor is developed for the measurement of gripping force in vision-based control. A microgripper mechanism integrated with a force sensing arm is fabricated by an excimer laser. The microgripper is actuated by a self-biased-SMA (Shape Memory Alloy) actuator. A computer-vision method through the ERES (Extended Regional Edge Statistics) algorithm is employed to track the motion of gripper. The position information of the gri...
Digit forces bias sensorimotor transformations underlying control of fingertip position
Directory of Open Access Journals (Sweden)
Daisuke eShibata
2014-08-01
Full Text Available Humans are able to modulate digit forces as a function of position despite changes in digit placement that might occur from trial to trial or when changing grip type for object manipulation. Although this phenomenon is likely to rely on sensing the position of the digits relative to each other and the object, the underlying mechanisms remain unclear. To address this question, we asked subjects (n = 30 to match perceived vertical distance between the center of pressure (CoP of the thumb and index finger pads (dy of the right hand (reference hand using the same hand (test hand. The digits of reference hand were passively placed collinearly (dy = 0 mm. Subjects were then asked to exert different combinations of normal and tangential digit forces (Fn and Ftan, respectively using the reference hand and then match the memorized dy using the test hand. The reference hand exerted Ftan of thumb and index finger in either same or opposite direction. We hypothesized that, when the tangential forces of the digits are produced in opposite directions, matching error (1 would be biased toward the directions of the tangential forces, and (2 would be greater when the remembered relative contact points are matched with negligible digit force production. For the test hand, digit forces were either negligible (0.5-1 N, 0 ± 0.25 N; Experiment 1 or the same as those exerted by the reference hand (Experiment 2. Matching error was biased towards the direction of digit tangential forces: thumb CoP was placed higher than the index finger CoP when thumb and index finger Ftan were directed upward and downward, respectively, and vice versa (p < 0.001. However, matching error was not dependent on whether the reference and test hand exerted similar or different forces. We propose that the expected sensory consequence of motor commands for tangential forces in opposite directions overrides estimation of fingertip position through haptic sensory feedback.
Using forced choice to test belief bias in syllogistic reasoning.
Trippas, Dries; Verde, Michael F; Handley, Simon J
2014-12-01
In deductive reasoning, believable conclusions are more likely to be accepted regardless of their validity. Although many theories argue that this belief bias reflects a change in the quality of reasoning, distinguishing qualitative changes from simple response biases can be difficult (Dube, Rotello, & Heit, 2010). We introduced a novel procedure that controls for response bias. In Experiments 1 and 2, the task required judging which of two simultaneously presented syllogisms was valid. Surprisingly, there was no evidence for belief bias with this forced choice procedure. In Experiment 3, the procedure was modified so that only one set of premises was viewable at a time. An effect of beliefs emerged: unbelievable conclusions were judged more accurately, supporting the claim that beliefs affect the quality of reasoning. Experiments 4 and 5 replicated and extended this finding, showing that the effect was mediated by individual differences in cognitive ability and analytic cognitive style. Although the positive findings of Experiments 3-5 are most relevant to the debate about the mechanisms underlying belief bias, the null findings of Experiments 1 and 2 offer insight into how the presentation of an argument influences the manner in which people reason. PMID:25218460
Forecast Bias Correction: A Second Order Method
Crowell, Sean
2010-01-01
The difference between a model forecast and actual observations is called forecast bias. This bias is due to either incomplete model assumptions and/or poorly known parameter values and initial/boundary conditions. In this paper we discuss a method for estimating corrections to parameters and initial conditions that would account for the forecast bias. A set of simple experiments with the logistic ordinary differential equation is performed using an iterative version of a first order version of our method to compare with the second order version of the method.
Codon Usage Bias and Determining Forces in Taenia solium Genome.
Yang, Xing; Ma, Xusheng; Luo, Xuenong; Ling, Houjun; Zhang, Xichen; Cai, Xuepeng
2015-12-01
The tapeworm Taenia solium is an important human zoonotic parasite that causes great economic loss and also endangers public health. At present, an effective vaccine that will prevent infection and chemotherapy without any side effect remains to be developed. In this study, codon usage patterns in the T. solium genome were examined through 8,484 protein-coding genes. Neutrality analysis showed that T. solium had a narrow GC distribution, and a significant correlation was observed between GC12 and GC3. Examination of an NC (ENC vs GC3s)-plot showed a few genes on or close to the expected curve, but the majority of points with low-ENC (the effective number of codons) values were detected below the expected curve, suggesting that mutational bias plays a major role in shaping codon usage. The Parity Rule 2 plot (PR2) analysis showed that GC and AT were not used proportionally. We also identified 26 optimal codons in the T. solium genome, all of which ended with either a G or C residue. These optimal codons in the T. solium genome are likely consistent with tRNAs that are highly expressed in the cell, suggesting that mutational and translational selection forces are probably driving factors of codon usage bias in the T. solium genome. PMID:26797435
Codon Usage Bias and Determining Forces in Taenia solium Genome.
Yang, Xing; Ma, Xusheng; Luo, Xuenong; Ling, Houjun; Zhang, Xichen; Cai, Xuepeng
2015-12-01
The tapeworm Taenia solium is an important human zoonotic parasite that causes great economic loss and also endangers public health. At present, an effective vaccine that will prevent infection and chemotherapy without any side effect remains to be developed. In this study, codon usage patterns in the T. solium genome were examined through 8,484 protein-coding genes. Neutrality analysis showed that T. solium had a narrow GC distribution, and a significant correlation was observed between GC12 and GC3. Examination of an NC (ENC vs GC3s)-plot showed a few genes on or close to the expected curve, but the majority of points with low-ENC (the effective number of codons) values were detected below the expected curve, suggesting that mutational bias plays a major role in shaping codon usage. The Parity Rule 2 plot (PR2) analysis showed that GC and AT were not used proportionally. We also identified 26 optimal codons in the T. solium genome, all of which ended with either a G or C residue. These optimal codons in the T. solium genome are likely consistent with tRNAs that are highly expressed in the cell, suggesting that mutational and translational selection forces are probably driving factors of codon usage bias in the T. solium genome.
A new polarization amplitude bias reduction method
Vidal, Matias; Leahy, J. P.; Dickinson, C.
2016-09-01
Polarization amplitude estimation is affected by a positive noise bias, particularly important in regions with low signal-to-noise ratio (SNR). We present a new approach to correct for this bias in the case there is additional information about the polarization angle. We develop the `known-angle estimator' that works in the special case when there is an independent and high SNR (≳ 2σ) measurement of the polarization angle. It is derived for the general case where the uncertainties in the Q, U Stokes parameters are not symmetric. This estimator completely corrects for the polarization bias if the polarization angle is perfectly known. In the realistic case, where the angle template has uncertainties, a small residual bias remains, but that is shown to be much smaller that the one left by other classical estimators. We also test our method with more realistic data, using the noise properties of the three lower frequency maps of Wilkinson Microwave Anisotropy Probe. In this case, the known-angle estimator also produces better results than methods that do not include the angle information. This estimator is therefore useful in the case where the polarization angle is expected to be constant over different data sets with different SNR.
Zero-Variance Zero-Bias Principle for Observables in quantum Monte Carlo: Application to Forces
Assaraf, R
2003-01-01
A simple and stable method for computing accurate expectation values of observable with Variational Monte Carlo (VMC) or Diffusion Monte Carlo (DMC) algorithms is presented. The basic idea consists in replacing the usual ``bare'' estimator associated with the observable by an improved or ``renormalized'' estimator. Using this estimator more accurate averages are obtained: Not only the statistical fluctuations are reduced but also the systematic error (bias) associated with the approximate VMC or (fixed-node) DMC probability densities. It is shown that improved estimators obey a Zero-Variance Zero-Bias (ZVZB) property similar to the usual Zero-Variance Zero-Bias property of the energy with the local energy as improved estimator. Using this property improved estimators can be optimized and the resulting accuracy on expectation values may reach the remarkable accuracy obtained for total energies. As an important example, we present the application of our formalism to the computation of forces in molecular system...
Self-Biased-SMA Drive PU Microgripper with Force Sensing in Visual Servo
Directory of Open Access Journals (Sweden)
Ren-Jung Chang
2013-06-01
Full Text Available An innovative design of a polyurethane microgripper system with force sensor is developed for the measurement of gripping force in vision-based control. A microgripper mechanism integrated with a force sensing arm is fabricated by an excimer laser. The microgripper is actuated by a self-biased-SMA (Shape Memory Alloy actuator. A computer-vision method through the ERES (Extended Regional Edge Statistics algorithm is employed to track the motion of gripper. The position information of the gripping point together with the deflection of the force sensing arm is utilized for sensing force. A fuzzy expert with a PI controller in a visual servo is employed to test the performance of sensing the gripping force in grasping of 38μm diameter metal rod. In the performance test, the microgripper system provides a maximum gripping size of 40μm, a maximum force resolution of 1μN and a maximum gripping force of 58μN.
Current-Induced Forces and Hot Spots in Biased Nanojunctions
DEFF Research Database (Denmark)
Lu, Jing Tao; Christensen, Rasmus Bjerregaard; Wang, Jian-Sheng;
2015-01-01
We investigate theoretically the interplay of current-induced forces (CIFs), Joule heating, and heat transport inside a current-carrying nanoconductor. We find that the CIFs, due to the electron-phonon coherence, can control the spatial heat dissipation in the conductor. This yields a significant...
The Air Force Officer Qualifying Test: Validity, Fairness, and Bias. Technical Report
Hardison, Chaitra M.; Sims, Carra S.; Wong, Eunice C.
2010-01-01
The Air Force has long recognized the importance of selecting the most qualified officers possible. For more than 60 years, it has relied on the Air Force Officer Qualifying Test (AFOQT) as one measure of those qualifications. A variety of concerns have been raised about whether the AFOQT is biased, too expensive, or even valid for predicting…
Restoring force method and response estimation
International Nuclear Information System (INIS)
The restoring force method is briefly outlined. Signal modifications that are necessary to successfully determine restoring force functions are discussed and illustrated. Restoring force functions for a base and a force excited system were determined and their effectiveness demonstrated by comparing measured and predicted signals. Additional developments that would make the restoring force method more general are suggested. 5 refs., 12 figs
Application of biasing techniques to the contributon Monte Carlo method
Energy Technology Data Exchange (ETDEWEB)
Dubi, A.; Gerstl, S.A.W.
1980-01-01
Recently, a new Monte Carlo Method called the Contribution Monte Carlo Method was developed. The method is based on the theory of contributions, and uses a new receipe for estimating target responses by a volume integral over the contribution current. The analog features of the new method were discussed in previous publications. The application of some biasing methods to the new contribution scheme is examined here. A theoretical model is developed that enables an analytic prediction of the benefit to be expected when these biasing schemes are applied to both the contribution method and regular Monte Carlo. This model is verified by a variety of numerical experiments and is shown to yield satisfying results, especially for deep-penetration problems. Other considerations regarding the efficient use of the new method are also discussed, and remarks are made as to the application of other biasing methods. 14 figures, 1 tables.
The shortwave radiative forcing bias of liquid and ice clouds from MODIS observations
Directory of Open Access Journals (Sweden)
L. Oreopoulos
2009-08-01
Full Text Available We present an assessment of the plane-parallel bias of the shortwave cloud radiative forcing (SWCRF of liquid and ice clouds at 1 deg scales using global MODIS (Terra and Aqua cloud optical property retrievals for four months of the year 2005 representative of the meteorological seasons. The (negative bias is estimated as the difference of SWCRF calculated using the Plane-Parallel Homogeneous (PPH approximation and the Independent Column Approximation (ICA. PPH calculations use MODIS-derived gridpoint means while ICA calculations use distributions of cloud optical thickness and effective radius. Assisted by a broadband solar radiative transfer algorithm, we find that the absolute value of global SWCRF bias of liquid clouds at the top of the atmosphere is about 6 W m^{−2} for MODIS overpass times while the SWCRF bias for ice clouds is smaller in absolute terms by about 0.7 W m^{−2}, but with stronger spatial variability. If effective radius variability is neglected and only optical thickness horizontal variations are accounted for, the absolute SWCRF biases increase by about 0.3–0.4 W m^{−2} on average. Marine clouds of both phases exhibit greater (more negative SWCRF biases than continental clouds. Finally, morning (Terra–afternoon (Aqua differences in SWCRF bias are much more pronounced for ice clouds, up to about 15% (Aqua producing stronger negative bias on global scales, with virtually all contribution to the difference coming from land areas. The substantial magnitude of the global SWCRF bias, which for clouds of both phases is collectively about 4 W m^{−2} for diurnal averages, should be considered a strong motivation for global climate modelers to accelerate efforts linking cloud schemes capable of subgrid condensate variability with appropriate radiative transfer schemes.
Dynamic atomic force microscopy methods
García, Ricardo; Pérez, Rubén
2002-09-01
In this report we review the fundamentals, applications and future tendencies of dynamic atomic force microscopy (AFM) methods. Our focus is on understanding why the changes observed in the dynamic properties of a vibrating tip that interacts with a surface make possible to obtain molecular resolution images of membrane proteins in aqueous solutions or to resolve atomic-scale surface defects in ultra high vacuum (UHV). Our description of the two major dynamic AFM modes, amplitude modulation atomic force microscopy (AM-AFM) and frequency modulation atomic force microscopy (FM-AFM) emphasises their common points without ignoring the differences in experimental set-ups and operating conditions. Those differences are introduced by the different feedback parameters, oscillation amplitude in AM-AFM and frequency shift and excitation amplitude in FM-AFM, used to track the topography and composition of a surface. The theoretical analysis of AM-AFM (also known as tapping-mode) emphasises the coexistence, in many situations of interests, of two stable oscillation states, a low and high amplitude solution. The coexistence of those oscillation states is a consequence of the presence of attractive and repulsive components in the interaction force and their non-linear dependence on the tip-surface separation. We show that key relevant experimental properties such as the lateral resolution, image contrast and sample deformation are highly dependent on the oscillation state chosen to operate the instrument. AM-AFM allows to obtain simultaneous topographic and compositional contrast in heterogeneous samples by recording the phase angle difference between the external excitation and the tip motion (phase imaging). Significant applications of AM-AFM such as high-resolution imaging of biomolecules and polymers, large-scale patterning of silicon surfaces, manipulation of single nanoparticles or the fabrication of single electron devices are also reviewed. FM-AFM (also called non
Reduction of systematic biases in regional climate downscaling through ensemble forcing
Energy Technology Data Exchange (ETDEWEB)
Yang, Hongwei; Wang, Bin [Chinese Academy of Sciences, LASG, Institute of Atmospheric Physics, Beijing (China); Wang, Bin [University of Hawaii at Manoa, Department of Meteorology, Honolulu, Hawaii (United States); University of Hawaii at Manoa, International Pacific Research Center, Honolulu, Hawaii (United States)
2012-02-15
Simulations of the East Asian summer monsoon for the period of 1979-2001 were carried out using the Weather Research and Forecast (WRF) model forced by three reanalysis datasets (NCEP-R2, ERA-40, and JRA-25). The experiments forced by different reanalysis data exhibited remarkable differences, primarily caused by uncertainties in the lateral boundary (LB) moisture fluxes over the Bay of Bengal and the Philippine Sea. The climatological mean water vapor convergence into the model domain computed from ERA-40 was about 24% higher than that from the NCEP-R2 reanalysis. We demonstrate that using the ensemble mean of NCEP-R2, ERA-40, and JRA-25 as LB forcing considerably reduced the biases in the model simulation. The use of ensemble forcing improved the performance in simulated mean circulation and precipitation, inter-annual variation in seasonal precipitation, and daily precipitation. The model simulated precipitation was superior to that in the reanalysis in both climatology and year-to-year variations, indicating the added value of dynamic downscaling. The results suggest that models having better performance under one set of LB forcing might worsen when another set of reanalysis data is used as LB forcing. Use of ensemble mean LB forcing for assessing regional climate model performance is recommended. (orig.)
DEFF Research Database (Denmark)
Nørlykke, Simon F.; Flyvbjerg, Henrik
2010-01-01
Optical tweezers and atomic force microscope (AFM) cantilevers are often calibrated by fitting their experimental power spectra of Brownian motion. We demonstrate here that if this is done with typical weighted least-squares methods, the result is a bias of relative size between -2/n and + 1/n...... on the value of the fitted diffusion coefficient. Here, n is the number of power spectra averaged over, so typical calibrations contain 10%-20% bias. Both the sign and the size of the bias depend on the weighting scheme applied. Hence, so do length-scale calibrations based on the diffusion coefficient....... The fitted value for the characteristic frequency is not affected by this bias. For the AFM then, force measurements are not affected provided an independent length-scale calibration is available. For optical tweezers there is no such luck, since the spring constant is found as the ratio...
CEO emotional bias and investment decision, Bayesian network method
Directory of Open Access Journals (Sweden)
Jarboui Anis
2012-08-01
Full Text Available This research examines the determinants of firms’ investment introducing a behavioral perspective that has received little attention in corporate finance literature. The following central hypothesis emerges from a set of recently developed theories: Investment decisions are influenced not only by their fundamentals but also depend on some other factors. One factor is the biasness of any CEO to their investment, biasness depends on the cognition and emotions, because some leaders use them as heuristic for the investment decision instead of fundamentals. This paper shows how CEO emotional bias (optimism, loss aversion and overconfidence affects the investment decisions. The proposed model of this paper uses Bayesian Network Method to examine this relationship. Emotional bias has been measured by means of a questionnaire comprising several items. As for the selected sample, it has been composed of some 100 Tunisian executives. Our results have revealed that the behavioral analysis of investment decision implies leader affected by behavioral biases (optimism, loss aversion, and overconfidence adjusts its investment choices based on their ability to assess alternatives (optimism and overconfidence and risk perception (loss aversion to create of shareholder value and ensure its place at the head of the management team.
Tip-bias-induced domain evolution in PMN-PT transparent ceramics via piezoresponse force microscopy
Zhao, K. Y.; Zhao, W.; Zeng, H. R.; Yu, H. Z.; Ruan, W.; Xu, K. Q.; Li, G. R.
2015-05-01
Piezoresponse force microscopy (PFM) was employed to investigate ferroelectric domain structures and their dynamic behavior of lead magnesium niobate-lead titanate [Pb(Mg1/3Nb2/3)O3-xPbTiO3 (PMN-PT)] transparent ceramics under an tip-bias-induced electric field. A remarkable effect of fluctuation of PT content on the domain configurations and domain dynamic response in PMN-PT transparent ferroelectric ceramics were found by PFM. Comparing with PMN-10%PT and PMN-20%PT, the reversed polarization of macrodomain area in PMN-35%PT and PMN-25%PT exhibits a relatively higher response behavior and better polarization retention performance under the PFM tip-bias-induced electric field, which correspond to their unique macroscopic electro-optic properties.
Energy Technology Data Exchange (ETDEWEB)
Garcia, M.M.; Jimenez, I.; Vazquez, L.; Gomez-Aleixandre, C.; Albella, J.M.; Sanchez, O. [Instituto de Ciencia de Materiales, C.S.I.C., Cantoblanco28049, Madrid (Spain); Terminello, L.J. [Lawrence Livermore National Laboratory, Livermore, California94551 (United States); Himpsel, F.J. [Department of Physics, University of Wisconsin--Madison, Madison, Wisconsin53706 (United States)
1998-04-01
The bias-enhanced nucleation of diamond on Si(100) has been studied by x-ray absorption near-edge spectroscopy (XANES) and atomic force microscopy, two techniques well suited to characterize nanometric crystallites. Diamond nuclei of {approximately}15nm are formed after 5 min of bias-enhanced treatment. The number of nuclei and its size increases with the time of application of the bias voltage. A nanocrystalline diamond film is attained after 20 min of bias-enhanced nucleation. At the initial nucleation stages, the Si substrate appears covered with diamond crystallites and graphite, without SiC being detected by XANES. {copyright} {ital 1998 American Institute of Physics.}
Nonlinear structural analysis using integrated force method
Indian Academy of Sciences (India)
N R B Krishnam Raju; J Nagabhushanam
2000-08-01
Though the use of the integrated force method for linear investigations is well-recognised, no efforts were made to extend this method to nonlinear structural analysis. This paper presents the attempts to use this method for analysing nonlinear structures. General formulation of nonlinear structural analysis is given. Typically highly nonlinear bench-mark problems are considered. The characteristic matrices of the elements used in these problems are developed and later these structures are analysed. The results of the analysis are compared with the results of the displacement method. It has been demonstrated that the integrated force method is equally viable and efficient as compared to the displacement method.
Sample preparation method for scanning force microscopy
Jankov, I R; Szente, R N; Carreno, M N P; Swart, J W; Landers, R
2001-01-01
We present a method of sample preparation for studies of ion implantation on metal surfaces. The method, employing a mechanical mask, is specially adapted for samples analysed by Scanning Force Microscopy. It was successfully tested on polycrystalline copper substrates implanted with phosphorus ions at an acceleration voltage of 39 keV. The changes of the electrical properties of the surface were measured by Kelvin Probe Force Microscopy and the surface composition was analysed by Auger Electron Spectroscopy.
Directory of Open Access Journals (Sweden)
J.-K. Lee
2015-11-01
Full Text Available There are many potential sources of the biases in the radar rainfall estimation process. This study classified the biases from the rainfall estimation process into the reflectivity measurement bias and the rainfall estimation bias by the Quantitative Precipitation Estimation (QPE model and also conducted the bias correction methods to improve the accuracy of the Radar-AWS Rainrate (RAR calculation system operated by the Korea Meteorological Administration (KMA. In the Z bias correction for the reflectivity biases occurred by measuring the rainfalls, this study utilized the bias correction algorithm. The concept of this algorithm is that the reflectivity of the target single-pol radars is corrected based on the reference dual-pol radar corrected in the hardware and software bias. This study, and then, dealt with two post-process methods, the Mean Field Bias Correction (MFBC method and the Local Gauge Correction method (LGC, to correct the rainfall estimation bias by the QPE model. The Z bias and rainfall estimation bias correction methods were applied to the RAR system. The accuracy of the RAR system was improved after correcting Z bias. For the rainfall types, although the accuracy of the Changma front and the local torrential cases was slightly improved without the Z bias correction the accuracy of the typhoon cases got worse than the existing results in particular. As a result of the rainfall estimation bias correction, the Z bias_LGC was especially superior to the MFBC method because the different rainfall biases were applied to each grid rainfall amount in the LGC method. For the rainfall types, the results of the Z bias_LGC showed that the rainfall estimates for all types was more accurate than only the Z bias and, especially, the outcomes in the typhoon cases was vastly superior to the others.
Bias annealing: A method for obtaining transition paths de novo
Hu, Jie; Ma, Ao; Dinner, Aaron R.
2006-09-01
Computational studies of dynamics in complex systems require means for generating reactive trajectories with minimum knowledge about the processes of interest. Here, we introduce a method for generating transition paths when an existing one is not already available. Starting from biased paths obtained from steered molecular dynamics, we use a Monte Carlo procedure in the space of whole trajectories to shift gradually to sampling an ensemble of unbiased paths. Application to basin-to-basin hopping in a two-dimensional model system and nucleotide-flipping by a DNA repair protein demonstrates that the method can efficiently yield unbiased reactive trajectories even when the initial steered dynamics differ significantly. The relation of the method to others and the physical basis for its success are discussed.
Directory of Open Access Journals (Sweden)
J.-K. Lee
2015-04-01
Full Text Available There are many potential sources of bias in the radar rainfall estimation process. This study classified the biases from the rainfall estimation process into the reflectivity measurement bias and QPE model bias and also conducted the bias correction methods to improve the accuracy of the Radar-AWS Rainrate (RAR calculation system operated by the Korea Meteorological Administration (KMA. For the Z bias correction, this study utilized the bias correction algorithm for the reflectivity. The concept of this algorithm is that the reflectivity of target single-pol radars is corrected based on the reference dual-pol radar corrected in the hardware and software bias. This study, and then, dealt with two post-process methods, the Mean Field Bias Correction (MFBC method and the Local Gauge Correction method (LGC, to correct rainfall-bias. The Z bias and rainfall-bias correction methods were applied to the RAR system. The accuracy of the RAR system improved after correcting Z bias. For rainfall types, although the accuracy of Changma front and local torrential cases was slightly improved without the Z bias correction, especially, the accuracy of typhoon cases got worse than existing results. As a result of the rainfall-bias correction, the accuracy of the RAR system performed Z bias_LGC was especially superior to the MFBC method because the different rainfall biases were applied to each grid rainfall amount in the LGC method. For rainfall types, Results of the Z bias_LGC showed that rainfall estimates for all types was more accurate than only the Z bias and, especially, outcomes in typhoon cases was vastly superior to the others.
CEO emotional bias and dividend policy: Bayesian network method
Azouzi Mohamed Ali; Jarboui Anis
2012-01-01
This paper assumes that managers, investors, or both behave irrationally. In addition, even though scholars have investigated behavioral irrationality from three angles, investor sentiment, investor biases and managerial biases, we focus on the relationship between one of the managerial biases, overconfidence and dividend policy. Previous research investigating the relationship between overconfidence and financial decisions has studied investment, financing decisions and firm values. However,...
Computing Method of Forces on Rivet
Directory of Open Access Journals (Sweden)
Ion DIMA
2014-03-01
Full Text Available This article aims to provide a quick methodology of forces calculation on rivet in single shear using the finite element method (FEM – NASTRAN/PATRAN. These forces can be used for the calculus of bearing, inter rivet buckling and riveting check. For this method to be efficient and fast, a macro has been developed based on this methodology described in the article. The macro was wrote in Visual Basic with Excel interface. In the beginning phase of any aircraft project, when the rivets type and position are not yet precisely known, the modelling of rivets, as attachment elements between items, is made node on node in the finite element model, without taking account of the rivets position. Although the rivets are not modelled in the finite element model, this method together with the macro enable a quick extraction and calculation of the forces on the rivet. This calculation of forces on rivet is intended to critical case, selected from the stress plots of NASTRAN for max. /min. principal stress and shear.
Detecting Bias in Selection for Higher Education: Three Different Methods
Kennet-Cohen, Tamar; Turvall, Elliot; Oren, Carmel
2014-01-01
This study examined selection bias in Israeli university admissions with respect to test language and gender, using three approaches for the detection of such bias: Cleary's model of differential prediction, boundary conditions for differential prediction and difference between "d's" (the Constant Ratio Model). The university…
A Polynomial Prediction Filter Method for Estimating Multisensor Dynamically Varying Biases
Institute of Scientific and Technical Information of China (English)
无
2007-01-01
The estimation of the sensor measurement biases in a multisensor system is vital for the sensor data fusion. A solution is provided for the estimation of dynamically varying multiple sensor biases without any knowledge of the dynamic bias model parameters. It is shown that the sensor bias pseudomeasurement can be dynamically obtained via a parity vector. This is accomplished by multiplying the sensor uncalibrated measurement equations by a projection matrix so that the measured variable is eliminated from the equations. Once the state equations of the dynamically varying sensor biases are modeled by a polynomial prediction filter, the dynamically varying multisensor biases can be obtained by Kalman filter. Simulation results validate that the proposed method can estimate the constant biases and dynamic biases of multisensors and outperforms the methods reported in literature.
CEO emotional bias and investment decision, Bayesian network method
Jarboui Anis; Mohamed Ali Azouzi
2012-01-01
This research examines the determinants of firms’ investment introducing a behavioral perspective that has received little attention in corporate finance literature. The following central hypothesis emerges from a set of recently developed theories: Investment decisions are influenced not only by their fundamentals but also depend on some other factors. One factor is the biasness of any CEO to their investment, biasness depends on the cognition and emotions, because some leaders use them as h...
Evaluating a Combined Bias Correction and Stochastic Downscaling Method
Volosciuk, Claudia; Maraun, Douglas; Vrac, Mathieu; Widmann, Martin
2016-04-01
Much of our knowledge about future changes in precipitation relies on global (GCM) and/or regional climate models (RCM) that have resolutions which are much coarser than typical spatial scales of extreme precipitation. The major problems with these projections are both climate model biases and the scale gap between grid box and point scale. Wong et al. presented a first attempt to jointly bias correct and downscale precipitation at daily scales. This approach however relied on spectrally nudged RCM simulations and was not able to post-process GCM biases. Previously, we have presented an extension of this approach that separates the downscaling from the bias correction and in principle is applicable to free running RCMs, such as those available from ENSEMBLES or CORDEX. In a first step, we bias correct the RCMs (EURO-CORDEX) against gridded observational datasets (e.g., E-OBS) at the same scale using a quantile mapping approach that relies on distribution transformation. To correct the whole precipitation distribution including extreme tails we apply a mixture distribution of a gamma distribution for the precipitation mass and a generalized Pareto distribution for the extreme tail. In a second step, we bridge the scale gap: we add small scale variability to the bias corrected precipitation time series using a vector generalized linear gamma model (VGLM gamma). To calibrate the VGLM gamma model we determine the statistical relationship between precipitation observations on different scales, i.e. between gridded (e.g., E-OBS) and station (ECA&D) observations. Here we present a comprehensive evaluation of this approach against 86 weather stations in Europe based on the VALUE perfect predictor experiment, including a comparison with standard bias correction techniques.
N3 Bias Field Correction Explained as a Bayesian Modeling Method
DEFF Research Database (Denmark)
Larsen, Christian Thode; Iglesias, Juan Eugenio; Van Leemput, Koen
2014-01-01
Although N3 is perhaps the most widely used method for MRI bias field correction, its underlying mechanism is in fact not well understood. Specifically, the method relies on a relatively heuristic recipe of alternating iterative steps that does not optimize any particular objective function....... In this paper we explain the successful bias field correction properties of N3 by showing that it implicitly uses the same generative models and computational strategies as expectation maximization (EM) based bias field correction methods. We demonstrate experimentally that purely EM-based methods are capable...... of producing bias field correction results comparable to those of N3 in less computation time....
Correcting for Partial Verification Bias: A Comparison of Methods
J.A.H. de Groot; K.J.M. Janssen; A.H. Zwinderman; P.M.M. Bossuyt; J.B. Reitsma; K.G.M. Moons
2011-01-01
PURPOSE: A common problem in diagnostic research is that the reference standard has not been carried out in all patients. This partial verification may lead to biased accuracy measures of the test under study. The authors studied the performance of multiple imputation and the conventional correction
Analysis of force-deconvolution methods in frequency-modulation atomic force microscopy
Joachim Welker; Esther Illek; Giessibl, Franz J.
2012-01-01
In frequency-modulation atomic force microscopy the direct observable is the frequency shift of an oscillating cantilever in a force field. This frequency shift is not a direct measure of the actual force, and thus, to obtain the force, deconvolution methods are necessary. Two prominent methods proposed by Sader and Jarvis (Sader–Jarvis method) and Giessibl (matrix method) are investigated with respect to the deconvolution quality. Both methods show a nontrivial dependence of the deconv...
Method for removing atomic-model bias in macromolecular crystallography
Terwilliger, Thomas C.
2006-08-01
Structure factor bias in an electron density map for an unknown crystallographic structure is minimized by using information in a first electron density map to elicit expected structure factor information. Observed structure factor amplitudes are combined with a starting set of crystallographic phases to form a first set of structure factors. A first electron density map is then derived and features of the first electron density map are identified to obtain expected distributions of electron density. Crystallographic phase probability distributions are established for possible crystallographic phases of reflection k, and the process is repeated as k is indexed through all of the plurality of reflections. An updated electron density map is derived from the crystallographic phase probability distributions for each one of the reflections. The entire process is then iterated to obtain a final set of crystallographic phases with minimum bias from known electron density maps.
Methods of Monte Carlo biasing using two-dimensional discrete ordinates adjoint flux
Energy Technology Data Exchange (ETDEWEB)
Tang, J.S.; Stevens, P.N.; Hoffman, T.J.
1976-06-01
Methods of biasing three-dimensional deep penetration Monte Carlo calculations using importance functions obtained from a two-dimensional discrete ordinates adjoint calculation have been developed. The important distinction was made between the applications of the point value and the event value to alter the random walk in Monte Carlo analysis of radiation transport. The biasing techniques developed are the angular probability biasing which alters the collision kernel using the point value as the importance function and the path length biasing which alters the transport kernel using the event value as the importance function. Source location biasings using the step importance function and the scalar adjoint flux obtained from the two-dimensional discrete ordinates adjoint calculation were also investigated. The effects of the biasing techniques to Monte Carlo calculations have been investigated for neutron transport through a thick concrete shield with a penetrating duct. Source location biasing, angular probability biasing, and path length biasing were employed individually and in various combinations. Results of the biased Monte Carlo calculations were compared with the standard Monte Carlo and discrete ordinates calculations.
Extended force density method and its expressions
Miki, Masaaki
2011-01-01
The objective of this work can be divided into two parts. The first one is to propose an extension of the force density method (FDM)(H.J. Schek, 1974), a form-finding method for prestressed cable-net structures. The second one is to present a review of various form-finding methods for tension structures, in the relation with the extended FDM. In the first part, it is pointed out that the original FDM become useless when it is applied to the prestressed structures that consist of combinations of both tension and compression members, while the FDM is usually advantageous in form-finding analysis of cable-nets. To eliminate the limitation, a functional whose stationary problem simply represents the FDM is firstly proposed. Additionally, the existence of a variational principle in the FDM is also indicated. Then, the FDM is extensively redefined by generalizing the formulation of the functional. As the result, the generalized functionals enable us to find the forms of tension structures that consist of combinatio...
DEFF Research Database (Denmark)
Chen, Jingzhe; Thygesen, Kristian S.; Jacobsen, Karsten W.
2012-01-01
We present an efficient implementation of a nonequilibrium Green's function method for self-consistent calculations of electron transport and forces in nanostructured materials. The electronic structure is described at the level of density functional theory using the projector augmented wave method...... over k points and real space makes the code highly efficient and applicable to systems containing several hundreds of atoms. The method is applied to a number of different systems, demonstrating the effects of bias and gate voltages, multiterminal setups, nonequilibrium forces, and spin transport....
A new method to measure galaxy bias by combining the density and weak lensing fields
Pujol, Arnau; Chang, Chihway; Gaztañaga, Enrique; Amara, Adam; Refregier, Alexandre; Bacon, David J.; Carretero, Jorge; Castander, Francisco J.; Crocce, Martin; Fosalba, Pablo; Manera, Marc; Vikram, Vinu
2016-10-01
We present a new method to measure redshift-dependent galaxy bias by combining information from the galaxy density field and the weak lensing field. This method is based on the work of Amara et al., who use the galaxy density field to construct a bias-weighted convergence field κg. The main difference between Amara et al.'s work and our new implementation is that here we present another way to measure galaxy bias, using tomography instead of bias parametrizations. The correlation between κg and the true lensing field κ allows us to measure galaxy bias using different zero-lag correlations, such as / or /. Our method measures the linear bias factor on linear scales, under the assumption of no stochasticity between galaxies and matter. We use the Marenostrum Institut de Ciències de l'Espai (MICE) simulation to measure the linear galaxy bias for a flux-limited sample (i < 22.5) in tomographic redshift bins using this method. This article is the first that studies the accuracy and systematic uncertainties associated with the implementation of the method and the regime in which it is consistent with the linear galaxy bias defined by projected two-point correlation functions (2PCF). We find that our method is consistent with a linear bias at the per cent level for scales larger than 30 arcmin, while non-linearities appear at smaller scales. This measurement is a good complement to other measurements of bias, since it does not depend strongly on σ8 as do the 2PCF measurements. We will apply this method to the Dark Energy Survey Science Verification data in a follow-up article.
DriftLess™, an innovative method to estimate and compensate for the biases of inertial sensors
Ruizenaar, M.G.H.; Kemp, R.A.W.
2014-01-01
In this paper a method is presented that allows for bias compensation of low-cost MEMS inertial sensors. It is based on the use of two sets of inertial sensors and a rotation mechanism that physically rotates the sensors in an alternating fashion. After signal processing, the biases of both sets of
MEASUREMENT OF ADHESION FORCES IN AIR WITH THE VIBRATION METHOD
Institute of Scientific and Technical Information of China (English)
Siegfried; Ripperger; Konrad; Hein
2005-01-01
The vibration method represents a practical method for the measurement of adhesion forces and adhesion force distributions. This method causes sinusoidally altemating stresses and yields detachment and contact forces between particles and substrate of the same order of magnitude. Alternating contact forces of the vibration method can cause an adhesion force intensification through flattening of asperities. The measuring principle of the vibration method and the analysis of experimental results are described in the article. Normal adhesion forces (pull-off forces) are measured using the vibration method and the colloidal probe technique. The results of both methods show good agreement for small particle sizes. The influence of the detachment force direction is shown by comparing tangential and normal adhesion forces measured using particle reentrainment in a turbulent air flow and the vibration method, respectively. The surface roughness of the substrate and the relative humidity are shown to significantly influence the measured adhesion forces. For the calculation of the adhesion forces, an approach by Rabinovich was combined with approximations of plastic micro asperity flattening. The Rabinovich approach accounts for roughness effects on the van der Waals force by incorporating the rms roughness of the interacting surfaces. rms-values of the particles and substrates were measured with atomic force microscopy at different scanning areas.
Are shear force methods adequately reported?
Holman, Benjamin W B; Fowler, Stephanie M; Hopkins, David L
2016-09-01
This study aimed to determine the detail to which shear force (SF) protocols and methods have been reported in the scientific literature between 2009 and 2015. Articles (n=734) published in peer-reviewed animal and food science journals and limited to only those testing the SF of unprocessed and non-fabricated mammal meats were evaluated. It was found that most of these SF articles originated in Europe (35.3%), investigated bovine species (49.0%), measured m. longissimus samples (55.2%), used tenderometers manufactured by Instron (31.2%), and equipped with Warner-Bratzler blades (68.8%). SF samples were also predominantly thawed prior to cooking (37.1%) and cooked sous vide, using a water bath (50.5%). Information pertaining to blade crosshead speed (47.5%), recorded SF resistance (56.7%), muscle fibre orientation when tested (49.2%), sub-section or core dimension (21.8%), end-point temperature (29.3%), and other factors contributing to SF variation were often omitted. This base failure diminishes repeatability and accurate SF interpretation, and must therefore be rectified.
Are shear force methods adequately reported?
Holman, Benjamin W B; Fowler, Stephanie M; Hopkins, David L
2016-09-01
This study aimed to determine the detail to which shear force (SF) protocols and methods have been reported in the scientific literature between 2009 and 2015. Articles (n=734) published in peer-reviewed animal and food science journals and limited to only those testing the SF of unprocessed and non-fabricated mammal meats were evaluated. It was found that most of these SF articles originated in Europe (35.3%), investigated bovine species (49.0%), measured m. longissimus samples (55.2%), used tenderometers manufactured by Instron (31.2%), and equipped with Warner-Bratzler blades (68.8%). SF samples were also predominantly thawed prior to cooking (37.1%) and cooked sous vide, using a water bath (50.5%). Information pertaining to blade crosshead speed (47.5%), recorded SF resistance (56.7%), muscle fibre orientation when tested (49.2%), sub-section or core dimension (21.8%), end-point temperature (29.3%), and other factors contributing to SF variation were often omitted. This base failure diminishes repeatability and accurate SF interpretation, and must therefore be rectified. PMID:27107727
A Method for Estimating BeiDou Inter-frequency Satellite Clock Bias
Directory of Open Access Journals (Sweden)
LI Haojun
2016-02-01
Full Text Available A new method for estimating the BeiDou inter-frequency satellite clock bias is proposed, considering the shortage of the current methods. The constant and variable parts of the inter-frequency satellite clock bias are considered in the new method. The data from 10 observation stations are processed to validate the new method. The characterizations of the BeiDou inter-frequency satellite clock bias are also analyzed using the computed results. The results of the BeiDou inter-frequency satellite clock bias indicate that it is stable in the short term. The estimated BeiDou inter-frequency satellite clock bias results are molded. The model results show that the 10 parameters of model for each satellite can express the BeiDou inter-frequency satellite clock bias well and the accuracy reaches cm level. When the model parameters of the first day are used to compute the BeiDou inter-frequency satellite clock bias of the second day, the accuracy also reaches cm level. Based on the stability and modeling, a strategy for the BeiDou satellite clock service is presented to provide the reference of our BeiDou.
Optimal attitude determination method in presence of noise and bias on different star sensors
Directory of Open Access Journals (Sweden)
Amir Moghtadaei Rad
2014-03-01
Full Text Available There are different attitude determination methods which have been used in satellite and spacecraft by star tracker. Each of these methods have its own advantages and disadvantages depending on their application, stochastic characteristic of noise on sensors (bias or noise, and weight of noise falling on different sensors. The present study has thus explored the major methods from two perspectives: the effect of input noise or bias on each star sensor and the corresponding weight of each noise or bias falling on each sensor. These aspects are compared in each method and the optimal method according to each condition is introduced. N Vector, Triad, Quest, Q method and least square method are the methods studied and simulated in this article. Finally, a comparison is made between the methods and the optimal method is introduced theoretically and practically. Keywords: Attitude Determination, Celestial Navigation, Triad, Quest, Least Square, Satellite.
A polygonal method for haptic force generation
Energy Technology Data Exchange (ETDEWEB)
Anderson, T. [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Electrical and Computer Engineering]|[Sandia National Labs., Albuquerque, NM (United States)
1996-12-31
Algorithms for computing forces and associated surface deformations (graphical and physical) are given, which, together with a force feedback device can be used to haptically display virtual objects. The Bendable Polygon algorithm, created at Sandia National Labs and the University of New Mexico, for visual rendering of computer generated surfaces is also presented. An implementation using the EIGEN virtual reality environment, and the PHANToM (Trademark) haptic interface, is reported together with suggestions for future research.
Method for exploiting bias in factor analysis using constrained alternating least squares algorithms
Keenan, Michael R.
2008-12-30
Bias plays an important role in factor analysis and is often implicitly made use of, for example, to constrain solutions to factors that conform to physical reality. However, when components are collinear, a large range of solutions may exist that satisfy the basic constraints and fit the data equally well. In such cases, the introduction of mathematical bias through the application of constraints may select solutions that are less than optimal. The biased alternating least squares algorithm of the present invention can offset mathematical bias introduced by constraints in the standard alternating least squares analysis to achieve factor solutions that are most consistent with physical reality. In addition, these methods can be used to explicitly exploit bias to provide alternative views and provide additional insights into spectral data sets.
Comparison of Parametric and Nonparametric Methods for Analyzing the Bias of a Numerical Model
Directory of Open Access Journals (Sweden)
Isaac Mugume
2016-01-01
Full Text Available Numerical models are presently applied in many fields for simulation and prediction, operation, or research. The output from these models normally has both systematic and random errors. The study compared January 2015 temperature data for Uganda as simulated using the Weather Research and Forecast model with actual observed station temperature data to analyze the bias using parametric (the root mean square error (RMSE, the mean absolute error (MAE, mean error (ME, skewness, and the bias easy estimate (BES and nonparametric (the sign test, STM methods. The RMSE normally overestimates the error compared to MAE. The RMSE and MAE are not sensitive to direction of bias. The ME gives both direction and magnitude of bias but can be distorted by extreme values while the BES is insensitive to extreme values. The STM is robust for giving the direction of bias; it is not sensitive to extreme values but it does not give the magnitude of bias. The graphical tools (such as time series and cumulative curves show the performance of the model with time. It is recommended to integrate parametric and nonparametric methods along with graphical methods for a comprehensive analysis of bias of a numerical model.
Directory of Open Access Journals (Sweden)
W. Terink
2010-01-01
Full Text Available In many climate impact studies hydrological models are forced with meteorological data without an attempt to assess the quality of these data. The objective of this study is to compare downscaled ERA15 (ECMWF-reanalysis data precipitation and temperature with observed precipitation and temperature and apply a bias correction to these forcing variables. Precipitation is corrected by fitting the mean and coefficient of variation (CV of the observations. Temperature is corrected by fitting the mean and standard deviation of the observations. It appears that the uncorrected ERA15 is too warm and too wet for most of the Rhine basin. The bias correction leads to satisfactory results, precipitation and temperature differences decreased significantly, although there are a few years for which the correction of precipitation is less satisfying. Corrections were largest during summer for both precipitation and temperature, and for September and October for precipitation only. Besides the statistics the correction method was intended to correct for, it is also found to improve the correlations for the fraction of wet days and lag-1 autocorrelations between ERA15 and the observations. For the validation period temperature is corrected very well, but for precipitation the RMSE of the daily difference between modeled and observed precipitation has increased for the corrected situation. When taking random years for calibration, and the remaining years for validation, the spread in the mean bias error (MBE becomes larger for the corrected precipitation during validation, but the overal average MBE has decreased.
Watanabe, Satoshi; Kanae, Shinjiro; Seto, Shinta; Yeh, Pat J.-F.; Hirabayashi, Yukiko; Oki, Taikan
2012-12-01
Bias-correction methods applied to monthly temperature and precipitation data simulated by multiple General Circulation Models (GCMs) are evaluated in this study. Although various methods have been proposed recently, an intercomparison among them using multiple GCM simulations has seldom been reported. Moreover, no previous methods have addressed the issue how to adequately deal with the changes of the statistics of bias-corrected variables from the historical to future simulations. In this study, a new method which conserves the changes of mean and standard deviation of the uncorrected model simulation data is proposed, and then five previous bias-correction methods as well as the proposed new method are intercompared by applying them to monthly temperature and precipitation data simulated from 12 GCMs in the Coupled Model Intercomparison Project (CMIP3) archives. Parameters of each method are calibrated by using 1948-1972 observed data and validated in the 1974-1998 period. These methods are then applied to the GCM future simulations (2073-2097) and the bias-corrected data are intercompared. For the historical simulations, negligible difference can be found between observed and bias-corrected data. However, the differences in future simulations are large dependent on the characteristics of each method. The new method successfully conserves the changes in the mean, standard deviation and the coefficient of variation before and after bias-correction. The differences of bias-corrected data among methods are discussed according to their respective characteristics. Importantly, this study classifies available correction methods into two distinct categories, and articulates important features for each of them.
A new method to compute standard-weight equations that reduces length-related bias
Gerow, K.G.; Anderson-Sprecher, R. C.; Hubert, W.A.
2005-01-01
We propose a new method for developing standard-weight (Ws) equations for use in the computation of relative weight (Wr) because the regression line-percentile (RLP) method often leads to length-related biases in Ws equations. We studied the structural properties of W s equations developed by the RLP method through simulations, identified reasons for biases, and compared Ws equations computed by the RLP method and the new method. The new method is similar to the RLP method but is based on means of measured weights rather than on means of weights predicted from regression models. The new method also models curvilinear W s relationships not accounted for by the RLP method. For some length-classes in some species, the relative weights computed from Ws equations developed by the new method were more than 20 Wr units different from those using Ws equations developed by the RLP method. We recommend assessment of published Ws equations developed by the RLP method for length-related bias and use of the new method for computing new Ws equations when bias is identified. ?? Copyright by the American Fisheries Society 2005.
Construct, item, and method bias of cognitive and personality tests in South Africa
Directory of Open Access Journals (Sweden)
D. Meiring
2005-10-01
Full Text Available Bias was studied for two cognitive tests and a personality test at three levels: the construct underlying the test (“construct bias", method-related aspects such as response sets (“method bias", and the items (“item bias". The sample consisted of 13 681 participants who had applied for entry-level jobs in the South African Police Service. The cognitive instruments produced very good construct equivalence and low item bias. However, various scales of the personality questionnaire revealed construct bias in various ethnic groups. The item bias in the personality scales was low. Method bias did not have any impact on the (small size of the cross-cultural differences in the personality scales. In addition, several personality scales revealed low internal consistencies, notably in the black groups. Opsomming Sydigheid is bestudeer vir twee kognitiewe toetse en ’n persoonlikheidstoets op drie vlakke: die konstruk onderliggend aan die toets (“konstruksydigheid�?, metode-verwante aspekte soos responspatrone (“metodesydigheid�?, en die items (“itemsydigheid�?. Die steekproef het bestaan uit 13 681 deelnemers wat aansoek gedoen het om intreevlak-poste in die Suid-Afrikaanse Polisiediens. Die kognitiewe instrumente het baie goeie konstrukekwivalensie en lae itemsydigheid getoon. Verskeie skale van die persoonlikheidsvraelys het egter konstruksydigheid in verskeie etniese groepe getoon. Die itemsydigheid in die persoonlikheidskale was laag. Metodesydigheid het nie enige uitwerking op die (klein omvang van die kruiskulturele verskille in die persoonlikheidskale gehad nie. Verder het verskeie persoonlikheidskale lae interne konsekwentheid getoon – veral in die swart groepe.
Assessing response bias from missing quality of life data: The Heckman method
Directory of Open Access Journals (Sweden)
Spertus John A
2004-09-01
Full Text Available Abstract Background The objective of this study was to demonstrate the use of the Heckman two-step method to assess and correct for bias due to missing health related quality of life (HRQL surveys in a clinical study of acute coronary syndrome (ACS patients. Methods We analyzed data from 2,733 veterans with a confirmed diagnosis of acute coronary syndromes (ACS, including either acute myocardial infarction or unstable angina. HRQL outcomes were assessed by the Short-Form 36 (SF-36 health status survey which was mailed to all patients who were alive 7 months following ACS discharge. We created multivariable models of 7-month post-ACS physical and mental health status using data only from the 1,660 survey respondents. Then, using the Heckman method, we modeled survey non-response and incorporated this into our initial models to assess and correct for potential bias. We used logistic and ordinary least squares regression to estimate the multivariable selection models. Results We found that our model of 7-month mental health status was biased due to survey non-response, while the model for physical health status was not. A history of alcohol or substance abuse was no longer significantly associated with mental health status after controlling for bias due to non-response. Furthermore, the magnitude of the parameter estimates for several of the other predictor variables in the MCS model changed after accounting for bias due to survey non-response. Conclusion Recognition and correction of bias due to survey non-response changed the factors that we concluded were associated with HRQL seven months following hospital admission for ACS as well as the magnitude of some associations. We conclude that the Heckman two-step method may be a valuable tool in the assessment and correction of selection bias in clinical studies of HRQL.
A scanning tunneling microscope break junction method with continuous bias modulation
Beall, Edward; Yin, Xing; Waldeck, David H.; Wierzbinski, Emil
2015-09-01
Single molecule conductance measurements on 1,8-octanedithiol were performed using the scanning tunneling microscope break junction method with an externally controlled modulation of the bias voltage. Application of an AC voltage is shown to improve the signal to noise ratio of low current (low conductance) measurements as compared to the DC bias method. The experimental results show that the current response of the molecule(s) trapped in the junction and the solvent media to the bias modulation can be qualitatively different. A model RC circuit which accommodates both the molecule and the solvent is proposed to analyze the data and extract a conductance for the molecule.Single molecule conductance measurements on 1,8-octanedithiol were performed using the scanning tunneling microscope break junction method with an externally controlled modulation of the bias voltage. Application of an AC voltage is shown to improve the signal to noise ratio of low current (low conductance) measurements as compared to the DC bias method. The experimental results show that the current response of the molecule(s) trapped in the junction and the solvent media to the bias modulation can be qualitatively different. A model RC circuit which accommodates both the molecule and the solvent is proposed to analyze the data and extract a conductance for the molecule. Electronic supplementary information (ESI) available: Additional current-time traces recorded for mesitylene, 2,4-dichlorotoluene, and 3,4-dichlorotoluene under different bias modulation frequencies, determined solvent capacitance values, and traces recorded under various geometrical constraints in the experimental cell. See DOI: 10.1039/c5nr04649a
A new method to measure galaxy bias by combining the density and weak lensing fields
Pujol, Arnau; Gaztañaga, Enrique; Amara, Adam; Refregier, Alexandre; Bacon, David J; Carretero, Jorge; Castander, Francisco J; Crocce, Martin; Fosalba, Pablo; Manera, Marc; Vikram, Vinu
2016-01-01
We present a new method to measure the redshift-dependent galaxy bias by combining information from the galaxy density field and the weak lensing field. This method is based on Amara et al. (2012), where they use the galaxy density field to construct a bias-weighted convergence field kg. The main difference between Amara et al. (2012) and our new implementation is that here we present another way to measure galaxy bias using tomography instead of bias parameterizations. The correlation between kg and the true lensing field k allows us to measure galaxy bias using different zero-lag correlations, such as / or /. This paper is the first that studies and systematically tests the robustness of this method in simulations. We use the MICE simulation suite, which includes a set of self-consistent N-body simulations, lensing maps, and mock galaxy catalogues. We study the accuracy and systematic uncertainties associated with the implementation of the method, and the regime where it is consistent with the linear galaxy...
Double Force Compensation Method to Enhance the Performance of a Null Balance Force Sensor
Choi, In-Mook; Choi, Dong-June; Kim, Soo Hyun
2002-06-01
Microforce measurement is becoming more essential as precision industries such as biomedicine, precision chemistry, semiconductor manufacturing, and so forth develop. A null balance method has been introduced in order to improve on force measurement performances involving a loadcell. The null-balance type force sensor is analyzed and designed for the improvement of measurement performances. The measurement range and the resolution are dependent on the force generation capacity and the various error sources. These characteristics are estimated and verified according to the mechanical sensitivity and the force compensation sensitivity. Two different coil systems are designed and tested experimentally. Double force compensation is proposed in order to obtain a large range and high resolution. The measurement range of the large coil system and the resolution of the small one are fully realized by the double compensation method. After manufacturing, a range over 300 gf and resolution under ± 0.1 mgf were obtained by the double compensation method.
Force prediction in cold rolling mills by polynomial methods
Directory of Open Access Journals (Sweden)
Nicu ROMAN
2007-12-01
Full Text Available A method for steel and aluminium strip thickness control is provided including a new technique for predictive rolling force estimation method by statistic model based on polynomial techniques.
He, Y Thomas; Ziemkiewicz, Paul F
2016-09-01
Aluminum is an important aquatic contaminant due to its ubiquity, toxicity and low regulatory discharge limits. Aluminum is mobilized in mining related, acidic drainage and is commonly a regulated pollutant. However, while aquatic toxicity studies and toxicity criteria are based on dissolved aluminum(Ald), discharge levels are, for statutory reasons, based on total recoverable aluminum (Alt). The rationale for using total recoverable aluminum recognizes the potential for the release of exchangeable, toxic cations or dissolution of metastable metal flocs in the event the discharge enters an acidic receiving stream. The digestion methods used in determining total recoverable metals are not meant to dissolve aluminosilicate clay particles but we found that they do, resulting in positively biased total recoverable aluminum values. This study explored the interaction between total suspended solids (TSS) and total recoverable aluminum using three digestion methods to evaluate which method introduced the least bias. Using field collected water and sediment samples from two coal mine drainage sites in Central West Virginia, three total recoverable digestion methods (USEPA Method 200.7, M1; USGS In-Bottle method, M2; and a Modified In-Bottle method, M3) were used to determine total recoverable aluminum across a range of total suspended solids concentrations. Baseline simulation experiments were conducted at pH 2.5, 3.5, 4.5 and 5.5 at different total suspended solids concentrations. Results indicated that dissolved aluminum did not respond to increasing total suspended solids concentrations while determined total recoverable aluminum increased with total suspended solids, indicating varying degrees of clay dissolution and, thus bias in the total recoverable aluminum concentration. While all three digestion methods overestimated total recoverable aluminum, at the same total suspended solids concentration, total recoverable aluminum extracted by USEPA Method 200.7 (M1) was
Wang, Y. P.; Lu, Z. P.; Sun, D. S.; Wang, N.
2016-01-01
In order to better express the characteristics of satellite clock bias (SCB) and improve SCB prediction precision, this paper proposed a new SCB prediction model which can take physical characteristics of space-borne atomic clock, the cyclic variation, and random part of SCB into consideration. First, the new model employs a quadratic polynomial model with periodic items to fit and extract the trend term and cyclic term of SCB; then based on the characteristics of fitting residuals, a time series ARIMA ~(Auto-Regressive Integrated Moving Average) model is used to model the residuals; eventually, the results from the two models are combined to obtain final SCB prediction values. At last, this paper uses precise SCB data from IGS (International GNSS Service) to conduct prediction tests, and the results show that the proposed model is effective and has better prediction performance compared with the quadratic polynomial model, grey model, and ARIMA model. In addition, the new method can also overcome the insufficiency of the ARIMA model in model recognition and order determination.
Adhesion Force Measurements of Polymer Particles by Detachment Field Method
Institute of Scientific and Technical Information of China (English)
Masashi Nagayama; Nobuyasu Sakurai; Tatsuaki Wada; Manabu Takeuchi
2004-01-01
The adhesion force distributions of polymer particles to aluminum substrates were measured by the detachment field method. Polymer particles with conducting surface treatment were used for the measurements.Further the conventional detachment field method was modified to be applicable to the adhesion force measurements of a single particle. The adhesion force of the polymer particles increased with an increase in relative humidity. The surface roughness of the substrate influenced the adhesion forces of particles significantly. The influence of the CF4 plasma treatment of the polymer particles and thin layer coating of the substrate surface on the adhesion forces of the polymer particles was also studied, and factors affecting adhesion forces of polymer particles are discussed.
von Bartheld, C.S.
2002-01-01
Investigators must choose between counting methods to quantify microscopic particles in tissues. The c o nventional profile-based ("model-based" or "2D-") counting methods have been criticized for their potential biases due to assumptions about shapes, sizes, and orientation of particles when converting profile counts into cell numbers. New stereological methods ("designbased" or "3D-") methods such as the optical disector or p hysical disector were initially i...
Directory of Open Access Journals (Sweden)
Xuhua Xia
2006-01-01
Full Text Available I show several types of topological biases in distance-based methods that use the least-squares method to evaluate branch lengths and the minimum evolution (ME or the Fitch-Margoliash (FM criterion to choose the best tree. For a 6-species tree, there are two tree shapes, one with three cherries (a cherry is a pair of adjacent leaves descending from the most recent common ancestor, and the other with two. When genetic distances are underestimated, the 3-cherry tree shape is favored with either the ME or FM criterion. When the genetic distances are overestimated, the ME criterion favors the 2-cherry tree, but the direction of bias with the FM criterion depends on whether negative branches are allowed, i.e. allowing negative branches favors the 3-cherry tree shape but disallowing negative branches favors the 2-cherry tree shape. The extent of the bias is explored by computer simulation of sequence evolution.
Willsky, A. S.; Deyst, J. J.; Crawford, B. S.
1975-01-01
The paper describes two self-test procedures applied to the problem of estimating the biases in accelerometers and gyroscopes on an inertial platform. The first technique is the weighted sum-squared residual (WSSR) test, with which accelerator bias jumps are easily isolated, but gyro bias jumps are difficult to isolate. The WSSR method does not take full advantage of the knowledge of system dynamics. The other technique is a multiple hypothesis method developed by Buxbaum and Haddad (1969). It has the advantage of directly providing jump isolation information, but suffers from computational problems. It might be possible to use the WSSR to detect state jumps and then switch to the BH system for jump isolation and estimate compensation.
Directory of Open Access Journals (Sweden)
Ann McCarthy
Full Text Available Bias is a pervasive problem when characterizing microbial communities. An important source is the difference in lysis efficiencies of different populations, which vary depending on the extraction protocol used. To avoid such biases impacting comparisons between gene and transcript abundances in the environment, the use of one protocol that simultaneously extracts both types of nucleic acids from microbial community samples has gained popularity. However, knowledge regarding tradeoffs to combined nucleic acid extraction protocols is limited, particularly regarding yield and biases in the observed community composition. Here, we evaluated a commercially available protocol for simultaneous extraction of DNA and RNA, which we adapted for freshwater microbial community samples that were collected on filters. DNA and RNA yields were comparable to other commonly used, but independent DNA and RNA extraction protocols. RNA protection agents benefited RNA quality, but decreased DNA yields significantly. Choice of extraction protocol influenced the perceived bacterial community composition, with strong method-dependent biases observed for specific phyla such as the Verrucomicrobia. The combined DNA/RNA extraction protocol detected significantly higher levels of Verrucomicrobia than the other protocols, and those higher numbers were confirmed by microscopic analysis. Use of RNA protection agents as well as independent sequencing runs caused a significant shift in community composition as well, albeit smaller than the shift caused by using different extraction protocols. Despite methodological biases, sample origin was the strongest determinant of community composition. However, when the abundance of specific phylogenetic groups is of interest, researchers need to be aware of the biases their methods introduce. This is particularly relevant if different methods are used for DNA and RNA extraction, in addition to using RNA protection agents only for RNA
Finite-Sample Bias Propagation in Autoregressive Estimation With the Yule–Walker Method
Broersen, P.M.T.
2009-01-01
The Yule-Walker (YW) method for autoregressive (AR) estimation uses lagged-product (LP) autocorrelation estimates to compute an AR parametric spectral model. The LP estimates only have a small triangular bias in the estimated autocorrelation function and are asymptotically unbiased. However, using t
A novel adaptive force control method for IPMC manipulation
Hao, Lina; Sun, Zhiyong; Li, Zhi; Su, Yunquan; Gao, Jianchao
2012-07-01
IPMC is a type of electro-active polymer material, also called artificial muscle, which can generate a relatively large deformation under a relatively low input voltage (generally speaking, less than 5 V), and can be implemented in a water environment. Due to these advantages, IPMC can be used in many fields such as biomimetics, service robots, bio-manipulation, etc. Until now, most existing methods for IPMC manipulation are displacement control not directly force control, however, under most conditions, the success rate of manipulations for tiny fragile objects is limited by the contact force, such as using an IPMC gripper to fix cells. Like most EAPs, a creep phenomenon exists in IPMC, of which the generated force will change with time and the creep model will be influenced by the change of the water content or other environmental factors, so a proper force control method is urgently needed. This paper presents a novel adaptive force control method (AIPOF control—adaptive integral periodic output feedback control), based on employing a creep model of which parameters are obtained by using the FRLS on-line identification method. The AIPOF control method can achieve an arbitrary pole configuration as long as the plant is controllable and observable. This paper also designs the POF and IPOF controller to compare their test results. Simulation and experiments of micro-force-tracking tests are carried out, with results confirming that the proposed control method is viable.
Fu, Haohao; Shao, Xueguang; Chipot, Christophe; Cai, Wensheng
2016-08-01
Proper use of the adaptive biasing force (ABF) algorithm in free-energy calculations needs certain prerequisites to be met, namely, that the Jacobian for the metric transformation and its first derivative be available and the coarse variables be independent and fully decoupled from any holonomic constraint or geometric restraint, thereby limiting singularly the field of application of the approach. The extended ABF (eABF) algorithm circumvents these intrinsic limitations by applying the time-dependent bias onto a fictitious particle coupled to the coarse variable of interest by means of a stiff spring. However, with the current implementation of eABF in the popular molecular dynamics engine NAMD, a trajectory-based post-treatment is necessary to derive the underlying free-energy change. Usually, such a posthoc analysis leads to a decrease in the reliability of the free-energy estimates due to the inevitable loss of information, as well as to a drop in efficiency, which stems from substantial read-write accesses to file systems. We have developed a user-friendly, on-the-fly code for performing eABF simulations within NAMD. In the present contribution, this code is probed in eight illustrative examples. The performance of the algorithm is compared with traditional ABF, on the one hand, and the original eABF implementation combined with a posthoc analysis, on the other hand. Our results indicate that the on-the-fly eABF algorithm (i) supplies the correct free-energy landscape in those critical cases where the coarse variables at play are coupled to either each other or to geometric restraints or holonomic constraints, (ii) greatly improves the reliability of the free-energy change, compared to the outcome of a posthoc analysis, and (iii) represents a negligible additional computational effort compared to regular ABF. Moreover, in the proposed implementation, guidelines for choosing two parameters of the eABF algorithm, namely the stiffness of the spring and the mass
The Truth and Bias Model of Judgment
West, Tessa V.; Kenny, David A.
2011-01-01
We present a new model for the general study of how the truth and biases affect human judgment. In the truth and bias model, judgments about the world are pulled by 2 primary forces, the truth force and the bias force, and these 2 forces are interrelated. The truth and bias model differentiates force and value, where the force is the strength of…
Novak, Janja; Bailoo, Jeremy D; Melotti, Luca; Rommen, Jonas; Würbel, Hanno
2015-01-01
Behavioural tests to assess affective states are widely used in human research and have recently been extended to animals. These tests assume that affective state influences cognitive processing, and that animals in a negative affective state interpret ambiguous information as expecting a negative outcome (displaying a negative cognitive bias). Most of these tests however, require long discrimination training. The aim of the study was to validate an exploration based cognitive bias test, using two different handling methods, as previous studies have shown that standard tail handling of mice increases physiological and behavioural measures of anxiety compared to cupped handling. Therefore, we hypothesised that tail handled mice would display a negative cognitive bias. We handled 28 female CD-1 mice for 16 weeks using either tail handling or cupped handling. The mice were then trained in an eight arm radial maze, where two adjacent arms predicted a positive outcome (darkness and food), while the two opposite arms predicted a negative outcome (no food, white noise and light). After six days of training, the mice were also given access to the four previously unavailable intermediate ambiguous arms of the radial maze and tested for cognitive bias. We were unable to validate this test, as mice from both handling groups displayed a similar pattern of exploration. Furthermore, we examined whether maze exploration is affected by the expression of stereotypic behaviour in the home cage. Mice with higher levels of stereotypic behaviour spent more time in positive arms and avoided ambiguous arms, displaying a negative cognitive bias. While this test needs further validation, our results indicate that it may allow the assessment of affective state in mice with minimal training-a major confound in current cognitive bias paradigms. PMID:26154309
Directory of Open Access Journals (Sweden)
Janja Novak
Full Text Available Behavioural tests to assess affective states are widely used in human research and have recently been extended to animals. These tests assume that affective state influences cognitive processing, and that animals in a negative affective state interpret ambiguous information as expecting a negative outcome (displaying a negative cognitive bias. Most of these tests however, require long discrimination training. The aim of the study was to validate an exploration based cognitive bias test, using two different handling methods, as previous studies have shown that standard tail handling of mice increases physiological and behavioural measures of anxiety compared to cupped handling. Therefore, we hypothesised that tail handled mice would display a negative cognitive bias. We handled 28 female CD-1 mice for 16 weeks using either tail handling or cupped handling. The mice were then trained in an eight arm radial maze, where two adjacent arms predicted a positive outcome (darkness and food, while the two opposite arms predicted a negative outcome (no food, white noise and light. After six days of training, the mice were also given access to the four previously unavailable intermediate ambiguous arms of the radial maze and tested for cognitive bias. We were unable to validate this test, as mice from both handling groups displayed a similar pattern of exploration. Furthermore, we examined whether maze exploration is affected by the expression of stereotypic behaviour in the home cage. Mice with higher levels of stereotypic behaviour spent more time in positive arms and avoided ambiguous arms, displaying a negative cognitive bias. While this test needs further validation, our results indicate that it may allow the assessment of affective state in mice with minimal training-a major confound in current cognitive bias paradigms.
Directory of Open Access Journals (Sweden)
Ju Hyoung Lee
2015-12-01
Full Text Available Bias correction is a very important pre-processing step in satellite data assimilation analysis, as data assimilation itself cannot circumvent satellite biases. We introduce a retrieval algorithm-specific and spatially heterogeneous Instantaneous Field of View (IFOV bias correction method for Soil Moisture and Ocean Salinity (SMOS soil moisture. To the best of our knowledge, this is the first paper to present the probabilistic presentation of SMOS soil moisture using retrieval ensembles. We illustrate that retrieval ensembles effectively mitigated the overestimation problem of SMOS soil moisture arising from brightness temperature errors over West Africa in a computationally efficient way (ensemble size: 12, no time-integration. In contrast, the existing method of Cumulative Distribution Function (CDF matching considerably increased the SMOS biases, due to the limitations of relying on the imperfect reference data. From the validation at two semi-arid sites, Benin (moderately wet and vegetated area and Niger (dry and sandy bare soils, it was shown that the SMOS errors arising from rain and vegetation attenuation were appropriately corrected by ensemble approaches. In Benin, the Root Mean Square Errors (RMSEs decreased from 0.1248 m3/m3 for CDF matching to 0.0678 m3/m3 for the proposed ensemble approach. In Niger, the RMSEs decreased from 0.14 m3/m3 for CDF matching to 0.045 m3/m3 for the ensemble approach.
Methods of Reducing Bias in Combined Thermal/Epithermal Neutron (CTEN) Assays of Heterogeneous Waste
Energy Technology Data Exchange (ETDEWEB)
Estep, R.J.; Melton, S.; Miko, D.
1998-11-17
We examined the effectiveness of two different methods for correcting CTEN passive and active assays for bias due to variations in the source position in different drum types. Both use the same drum-averaged correction determined from a neural network trained to active flux monitor ratios as a starting point. One method then uses a neural network to obtain a spatial correction factor sensitive to the source location. The other method uses emission tomography. Both methods were found to give significantly improved assay accuracy over the drum-averaged correction, although more study is needed to determine which method works better.
Bias in diet determination: incorporating traditional methods in Bayesian mixing models.
Directory of Open Access Journals (Sweden)
Valentina Franco-Trecu
Full Text Available There are not "universal methods" to determine diet composition of predators. Most traditional methods are biased because of their reliance on differential digestibility and the recovery of hard items. By relying on assimilated food, stable isotope and Bayesian mixing models (SIMMs resolve many biases of traditional methods. SIMMs can incorporate prior information (i.e. proportional diet composition that may improve the precision in the estimated dietary composition. However few studies have assessed the performance of traditional methods and SIMMs with and without informative priors to study the predators' diets. Here we compare the diet compositions of the South American fur seal and sea lions obtained by scats analysis and by SIMMs-UP (uninformative priors and assess whether informative priors (SIMMs-IP from the scat analysis improved the estimated diet composition compared to SIMMs-UP. According to the SIMM-UP, while pelagic species dominated the fur seal's diet the sea lion's did not have a clear dominance of any prey. In contrast, SIMM-IP's diets compositions were dominated by the same preys as in scat analyses. When prior information influenced SIMMs' estimates, incorporating informative priors improved the precision in the estimated diet composition at the risk of inducing biases in the estimates. If preys isotopic data allow discriminating preys' contributions to diets, informative priors should lead to more precise but unbiased estimated diet composition. Just as estimates of diet composition obtained from traditional methods are critically interpreted because of their biases, care must be exercised when interpreting diet composition obtained by SIMMs-IP. The best approach to obtain a near-complete view of predators' diet composition should involve the simultaneous consideration of different sources of partial evidence (traditional methods, SIMM-UP and SIMM-IP in the light of natural history of the predator species so as to reliably
Impact of Three Illumina Library Construction Methods on GC Bias and HLA Genotype Calling
Lan, James H; Yin, Yuxin; Reed, Elaine F; Moua, Kevin; Thomas, Kimberly; Zhang, Qiuheng
2016-01-01
Next-generation sequencing (NGS) is increasingly recognized for its ability to overcome allele ambiguity and deliver high-resolution typing in the human leukocyte antigen (HLA) system. Using this technology, non-uniform read distribution can impede the reliability of variant detection, which renders high-confidence genotype calling particularly difficult to achieve in the polymorphic HLA complex. Recently, library construction has been implicated as the dominant factor in instigating coverage bias. To study the impact of this phenomenon on HLA genotyping, we performed long-range PCR on 12 samples to amplify HLA-A, -B, -C, -DRB1, and -DQB1, and compared the relative contribution of three Illumina library construction methods (TruSeq Nano, Nextera, Nextera XT) in generating downstream bias. Here, we show high GC% to be a good predictor of low sequencing depth. Compared to standard TruSeq Nano, GC bias was more prominent in transposase-based protocols, particularly Nextera XT, likely through a combination of transposase insertion bias being coupled with a high number of PCR enrichment cycles. Importantly, our findings demonstrate non-uniform read depth can have a direct and negative impact on the robustness of HLA genotyping, which has clinical implications for users when choosing a library construction strategy that aims to balance cost and throughput with data quality. PMID:25543015
Determine the galaxy bias factors on large scales using bispectrum method
Guo, Hong
2009-01-01
We study whether the bias factors of galaxies can be unbiasedly recovered from their power spectra and bispectra. We use a set of numerical N-body simulations and construct large mock galaxy catalogs based upon the semi-analytical model of Croton et al. (2006). We measure the reduced bispectra for galaxies of different luminosity, and determine the linear and first nonlinear bias factors from their bispectra. We find that on large scales down to that of the wavenumber k=0.1h/Mpc, the bias factors b1 and b2 are nearly constant, and b1 obtained with the bispectrum method agrees very well with the expected value. The nonlinear bias factor b2 is negative, except for the most luminous galaxies with M<-23 which have a positive b2. The behavior of b2 of galaxies is consistent with the b2 mass dependence of their host halos. We show that it is essential to have an accurate estimation of the dark matter bispectrum in order to have an unbiased measurement of b1 and b2. We also test the analytical approach of incorpo...
A Simple Method for Measuring Tensile Force with Piezoelectric Patch
Institute of Scientific and Technical Information of China (English)
ZHANG Zhi-Wen; JIANG Zhong-Wei; Testuya Morisaki
2007-01-01
@@ We propose a simple method for monitoring the axial tensile and compressive force in a structure by using a piezoelectric patch with the piezoelectric impedance based measurement. A simple approximate equation for estimating the tensile force in two different conditions, which can be calculated easily if the natural frequencies in two different states are measured, is explained in detail. On another front, the natural frequency can be very easily measured by a piezoelectric element by bonding it on the measuring subject structure, because its electric impedance of piezoelement is related to the structural mechanical impedance. Furthermore, an experiment for measuring a tensile force in a simple supported beam is carried out for validating the proposed method. The results show a good accuracy in estimating the tensile force variation by the natural frequency change measured from the piezoelement.
Multilinear Biased Discriminant Analysis: A Novel Method for Facial Action Unit Representation
Khademi, Mahmoud; Manzuri-Shalmani, Mohammad T
2010-01-01
In this paper a novel efficient method for representation of facial action units by encoding an image sequence as a fourth-order tensor is presented. The multilinear tensor-based extension of the biased discriminant analysis (BDA) algorithm, called multilinear biased discriminant analysis (MBDA), is first proposed. Then, we apply the MBDA and two-dimensional BDA (2DBDA) algorithms, as the dimensionality reduction techniques, to Gabor representations and the geometric features of the input image sequence respectively. The proposed scheme can deal with the asymmetry between positive and negative samples as well as curse of dimensionality dilemma. Extensive experiments on Cohn-Kanade database show the superiority of the proposed method for representation of the subtle changes and the temporal information involved in formation of the facial expressions. As an accurate tool, this representation can be applied to many areas such as recognition of spontaneous and deliberate facial expressions, multi modal/media huma...
On Stein's method for products of normal random variables and zero bias couplings
Gaunt, Robert E.
2013-01-01
In this paper we extend Stein's method to the distribution of the product of $n$ independent mean zero normal random variables. A Stein equation is obtained for this class of distributions, which reduces to the classical normal Stein equation in the case $n=1$. This Stein equation motivates a generalisation of the zero bias transformation. We establish properties of this new transformation, and illustrate how they may be used together with the Stein equation to assess distributional distances...
MCNP/TORT coupling vs. MCNP biasing transport methods for PWR applications
International Nuclear Information System (INIS)
This paper presents the coupling methodology of the Monte Carlo code MCNP5 and the deterministic SN TORT, to meet the AREVA needs for PWR reactors analysis, but also BWR and GEN IV reactors. In general the long-range transport of neutron and gamma particles outside the core using only Monte Carlo calculations requires prohibitive computation time, if no biasing is included, to guide the particle population to spread towards the chosen target. This biasing becomes essential, if computing resources are limited. The disadvantage of this approach lies in the preparation of such biasing, particularly for non-standard configurations. An alternate method is proposed, with the coupling of the two codes specified above. The MCNP5 code is used to calculate the in-core neutron or gamma sources. The neutron/gamma particles are transported to the outside of the core and deposited on a predetermined outer surface. The surface source is subsequently propagated in SN/finite difference method. The convergence of the SN calculations is relatively short (few hours), which leads to a result in only about a half day, including MCNP5. A first physical validation of this coupling is obtained for the N4 French reactor. The thermal epithermal and fast fluxes are evaluated. A very good agreement is obtained for the neutron flux >1 eV; the deviations are below 5% for this part of spectrum. Finally a comparison is presented to demonstrate the interest or not of the coupling MCNP/TORT methodology vs. existing biasing methods in MCNP5. (author)
Influence of bias on properties of carbon films deposited by MCECR plasma sputtering method
Institute of Scientific and Technical Information of China (English)
CAI Chang-long; DIAO Dong-feng; S.Miyake; T.Matsumoto
2004-01-01
The mirror-confinement-type electron cyclotron resonance(MCECR) plasma source has high plasma density and high electron temperature. It is quite useful in many plasma processing, and has been used for etching and thin-film deposition. The carbon films with 40 nm thickness were deposited by MCECR plasma sputtering method on Si, and the influence of substrate bias on the properties of carbon films was studied. The bonding structure of the film was analyzed by the X-ray photoelectron spectroscopy(XPS), the tribological properties were measured by the pin-on-disk(POD) tribometer, the nanohardness of the films was measured by the nanoindenter, and the deposition speed and the refractive index were measured by the ellipse meter. The better substrate bias was obtained, and the better properties of carbon films were obtained.
Seo, Ji-Hoon; Kim, Gang-Jun; Son, Donghee; Lee, Nam-Hyun; Kang, Yongha; Kang, Bongkoo
2016-08-01
We propose a method to predict the length dependency of the magnitude of degradation caused by negative bias temperature instability (NBTI) stress applied to a p-MOSFET. Threshold voltage degradation ΔV th varied according to the drain bias V d, during the measurement of drain current I d. The depletion length L dep into the channel was calculated based on a particular V d value and the channel doping concentration. L dep was used to extract the channel edge region length L edge, then the center channel region length L cen was obtained by subtracting L edge from the gate length L gate. We proposed an equation that uses L dep, L cen, L edge and degree of ΔV th variation to calculate ΔV th according to L gate while the p-MOSFET is under NBTI stress. Equation estimates of ΔV th at different L gate were similar to measurements.
Detection of forced oscillations in power systems with multichannel methods
Energy Technology Data Exchange (ETDEWEB)
Follum, James D. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
2015-09-30
The increasing availability of high fidelity, geographically dispersed measurements in power systems improves the ability of researchers and engineers to study dynamic behaviors in the grid. One such behavior that is garnering increased attention is the presence of forced oscillations. Power system engineers are interested in forced oscillations because they are often symptomatic of the malfunction or misoperation of equipment. Though the resulting oscillation is not always large in amplitude, the root cause may be serious. In this report, multi-channel forced oscillation detection methods are developed. These methods leverage previously developed detection approaches based on the periodogram and spectral-coherence. Making use of geographically distributed channels of data is shown to improved detection performance and shorten the delay before an oscillation can be detected in the online environment. Results from simulated and measured power system data are presented.
Directory of Open Access Journals (Sweden)
Cris Beauchemin
2011-07-01
Full Text Available This paper provides a methodological assessment of the advantages and drawbacks of the origin-based snowballing technique as a reliable method to construct representative samples of international migrants in destination areas. Using data from the MAFE-Senegal Project, our results indicate that this is a very risky method in terms of quantitative success. Besides, it implies some clear selection biases: it over-represents migrants more strongly connected to their home country, and it tends to overestimate both poverty in households at origin and the influence of previous migration experiences of social networks on individuals' out-migration.
Laser measurement method of forced vibration in optical systems
International Nuclear Information System (INIS)
A forced vibration measurement method by laser combining the laser signal and high frequency CCD in optical systems is introduced. The method solves the conversion problem between the vibration signal and laser signal in optical systems, which can not only measure the impact of vibration on the beam stability, but also acquire the frequency characteristics of vibration signals. Forced vibration in an optical system is measured when the frequencies of vibration signals are 150 Hz and 200 Hz by using the method and the attributes of the vibration signals obtained fits those of the input signals. Test and analysis results demonstrate that the method has a time amplitude uncertainty of 6.25 μm and frequency resolution of 2 Hz. The handy and efficient method, whose measurement is precise, has been applied to the beam pointing stability study of the multiplexing excimer MOPA laser targeting test platform accordingly. (authors)
A novel method for correcting scanline-observational bias of discontinuity orientation.
Huang, Lei; Tang, Huiming; Tan, Qinwen; Wang, Dingjian; Wang, Liangqing; Ez Eldin, Mutasim A M; Li, Changdong; Wu, Qiong
2016-01-01
Scanline observation is known to introduce an angular bias into the probability distribution of orientation in three-dimensional space. In this paper, numerical solutions expressing the functional relationship between the scanline-observational distribution (in one-dimensional space) and the inherent distribution (in three-dimensional space) are derived using probability theory and calculus under the independence hypothesis of dip direction and dip angle. Based on these solutions, a novel method for obtaining the inherent distribution (also for correcting the bias) is proposed, an approach which includes two procedures: 1) Correcting the cumulative probabilities of orientation according to the solutions, and 2) Determining the distribution of the corrected orientations using approximation methods such as the one-sample Kolmogorov-Smirnov test. The inherent distribution corrected by the proposed method can be used for discrete fracture network (DFN) modelling, which is applied to such areas as rockmass stability evaluation, rockmass permeability analysis, rockmass quality calculation and other related fields. To maximize the correction capacity of the proposed method, the observed sample size is suggested through effectiveness tests for different distribution types, dispersions and sample sizes. The performance of the proposed method and the comparison of its correction capacity with existing methods are illustrated with two case studies. PMID:26961249
Influence of Bias on the Properties of Carbon Nitride Films Prepared by Vacuum Cathodic Arc Method
Institute of Scientific and Technical Information of China (English)
Zhimin ZHOU; Lifang XIA; Mingren SUN
2004-01-01
Carbon nitride films have been synthesized in a wide range of biases from 0 to -900 V by vacuum cathodic arc method. The N content was about 12.0～22.0 at. Pct. Upon increasing the biases from 0 to -100 V, the N content increased from 15.0 to 22.0 at. Pct which could be attributed to the knot-on effect. While the further increasing biases led to the gradual falling of the N content to 12.0 at. Pct at -900 V due to the enhancement of the sputtering effect. Below -200 V, with the increasing biases the sp2C fraction in the films decreased, as a result of which the I(D)/I(G) fell in the Raman spectra and the sp peaks also showed the decreasing tendency relative to the s peaks in the VBXPS (valence band X-ray photoelectron spectroscopy). While above -200 V, the sp2C fraction increased and the films became graphitinized gradually, accompanying which theI(D)/I(G) rose from -200 V to -300 V and the Raman spectra even showed the graphite characteristic above -300 V and the sp peaks rose again relative to the s peak. The carbon nitride films mainly consist of three types of bonding: CC, sp2CN and sp3CN bonds. In the first stage the sp3CN relative ratio rises and falls in the second stage, which corresponded well with the variation of the sp2C in the films. The subplantation mechanism resulting from the effect of ion energy played an important role in decidingthe variation of the microstructure of the carbon nitride films.
Institute of Scientific and Technical Information of China (English)
Xudong Yu; Yu Wang; Guo Wei; Pengfei Zhang; Xingwu Long
2011-01-01
Bias of ring-laser-gyroscope (RLG) changes with temperature in a nonlinear way. This is an important restraining factor for improving the accuracy of RLG. Considering the limitations of least-squares regression and neural network, we propose a new method of temperature compensation of RLG bias-building function regression model using least-squares support vector machine (LS-SVM). Static and dynamic temperature experiments of RLG bias are carried out to validate the effectiveness of the proposed method. Moreover,the traditional least-squares regression method is compared with the LS-SVM-based method. The results show the maximum error of RLG bias drops by almost two orders of magnitude after static temperature compensation, while bias stability of RLG improves by one order of magnitude after dynamic temperature compensation. Thus, the proposed method reduces the influence of temperature variation on the bias of the RLG effectively and improves the accuracy of the gyro scope considerably.%@@ Bias of ring-laser-gyroscope (RLG) changes with temperature in a nonlinear way.This is an important restraining factor for improving the accuracy of RLG.Considering the limitations of least-squares regression and neural network, we propose a new method of temperature compensation of RLG bias-building function regression model using least-squares support vector machine (LS-SVM).Static and dynamic temperature experiments of RLG bias are carried out to validate the effectiveness of the proposed method.Moreover,the traditional least-squares regression method is compared with the LS-SVM-based method.
Modeling Enzymatic Transition States by Force Field Methods
DEFF Research Database (Denmark)
Hansen, Mikkel Bo; Jensen, Hans Jørgen Aagaard; Jensen, Frank
2009-01-01
The SEAM method, which models a transition structure as a minimum on the seam of two diabatic surfaces represented by force field functions, has been used to generate 20 transition structures for the decarboxylation of orotidine by the orotidine-5'-monophosphate decarboxylase enzyme. The dependence...... by various electronic structure methods, where part of the enzyme is represented by a force field description and the effects of the solvent are represented by a continuum model. The relative energies vary by several hundreds of kJ/mol between the transition structures, and tests showed that a large part...... of this variation is due to changes in the enzyme structure at distances more than 5 Å from the active site. There are significant differences between the results obtained by pure quantum methods and those from mixed quantum and molecular mechanics methods....
Institute of Scientific and Technical Information of China (English)
Yang Shi; Zhaosheng Yu; Xueming Shao
2010-01-01
In this paper,we combine the direct-forcing fictitious domain(DF/FD)method and the sharp interface method to resolve the problem of particle dielectrophoresis in two dimensions,The flow field and the motion of particles are solved with the DF/FD method,the electric field is solved with the sharp interface method,and the electrostatic force on the particles is computed using the Maxwell stress tensor method.The proposed method is validated via three problems: effective conductivity of particle composite between two planar plates,cell trapping in a channel,and motion of particles due to both conventional and traveling wave dielectrophoretic forces.
Witzke, V; Favier, B
2016-01-01
Shear flows are ubiquitous in astrophysical objects including planetary and stellar interiors, where their dynamics can have significant impact on thermo-chemical processes. Investigating the complex dynamics of shear flows requires numerical calculations that provide a long time evolution of the system. To achieve a sufficiently long lifetime in a local numerical model the system has to be forced externally. However, at present, there exist several different forcing methods to sustain large-scale shear flows in local models. In this paper we examine and compare various methods used in the literature in order to resolve their respective applicability and limitations. These techniques are compared during the exponential growth phase of a shear flow instability, such as the Kelvin-Helmholtz (KH) instability, and some are examined during the subsequent non-linear evolution. A linear stability analysis provides reference for the growth rate of the most unstable modes in the system and a detailed analysis of the e...
Witzke, V.; Silvers, L. J.; Favier, B.
2016-08-01
Shear flows are ubiquitous in astrophysical objects including planetary and stellar interiors, where their dynamics can have significant impact on thermo-chemical processes. Investigating the complex dynamics of shear flows requires numerical calculations that provide a long time evolution of the system. To achieve a sufficiently long lifetime in a local numerical model the system has to be forced externally. However, at present, there exist several different forcing methods to sustain large-scale shear flows in local models. In this paper we examine and compare various methods used in the literature in order to resolve their respective applicability and limitations. These techniques are compared during the exponential growth phase of a shear flow instability, such as the Kelvin-Helmholtz (KH) instability, and some are examined during the subsequent non-linear evolution. A linear stability analysis provides reference for the growth rate of the most unstable modes in the system and a detailed analysis of the energetics provides a comprehensive understanding of the energy exchange during the system's evolution. Finally, we discuss the pros and cons of each forcing method and their relation with natural mechanisms generating shear flows.
Scalable force directed graph layout algorithms using fast multipole methods
Yunis, Enas
2012-06-01
We present an extension to ExaFMM, a Fast Multipole Method library, as a generalized approach for fast and scalable execution of the Force-Directed Graph Layout algorithm. The Force-Directed Graph Layout algorithm is a physics-based approach to graph layout that treats the vertices V as repelling charged particles with the edges E connecting them acting as springs. Traditionally, the amount of work required in applying the Force-Directed Graph Layout algorithm is O(|V|2 + |E|) using direct calculations and O(|V| log |V| + |E|) using truncation, filtering, and/or multi-level techniques. Correct application of the Fast Multipole Method allows us to maintain a lower complexity of O(|V| + |E|) while regaining most of the precision lost in other techniques. Solving layout problems for truly large graphs with millions of vertices still requires a scalable algorithm and implementation. We have been able to leverage the scalability and architectural adaptability of the ExaFMM library to create a Force-Directed Graph Layout implementation that runs efficiently on distributed multicore and multi-GPU architectures. © 2012 IEEE.
Forced vibration of flexible body systems. A dynamic stiffness method
Liu, T. S.; Lin, J. C.
1993-10-01
Due to the development of high speed machinery, robots, and aerospace structures, the research of flexible body systems undergoing both gross motion and elastic deformation has seen increasing importance. The finite element method and modal analysis are often used in formulating equations of motion for dynamic analysis of the systems which entail time domain, forced vibration analysis. This study develops a new method based on dynamic stiffness to investigate forced vibration of flexible body systems. In contrast to the conventional finite element method, shape functions and stiffness matrices used in this study are derived from equations of motion for continuum beams. Hence, the resulting shape functions are named as dynamic shape functions. By applying the dynamic shape functions, the mass and stiffness matrices of a beam element are derived. The virtual work principle is employed to formulate equations of motion. Not only the coupling of gross motion and elastic deformation, but also the stiffening effect of axial forces is taken into account. Simulation results of a cantilever beam, a rotating beam, and a slider crank mechanism are compared with the literature to verify the proposed method.
Selva Kumar, C; Nair, Rahul R; Sivaramakrishnan, K G; Ganesh, D; Janarthanan, S; Arunachalam, M; Sivaruban, T
2012-12-01
Forces that influence the evolution of synonymous codon usage bias are analyzed in six species of three basal orders of aquatic insects. The rationale behind choosing six species of aquatic insects (three from Ephemeroptera, one from Plecoptera, and two from Odonata) for the present analysis is based on phylogenetic position at the basal clades of the Order Insecta facilitating the understanding of the evolution of codon bias and of factors shaping codon usage patterns in primitive clades of insect lineages and their subtle differences in some of their ecological and environmental requirements in terms of habitat-microhabitat requirements, altitudinal preferences, temperature tolerance ranges, and consequent responses to climate change impacts. The present analysis focuses on open reading frames of the 13 protein-coding genes in the mitochondrial genome of six carefully chosen insect species to get a comprehensive picture of the evolutionary intricacies of codon bias. In all the six species, A and T contents are observed to be significantly higher than G and C, and are used roughly equally. Since transcription hypothesis on codon usage demands A richness and T poorness, it is quite likely that mutation pressure may be the key factor associated with synonymous codon usage (SCU) variations in these species because the mutation hypothesis predicts AT richness and GC poorness in the mitochondrial DNA. Thus, AT-biased mutation pressure seems to be an important factor in framing the SCU variation in all the selected species of aquatic insects, which in turn explains the predominance of A and T ending codons in these species. This study does not find any association between microhabitats and codon usage variations in the mitochondria of selected aquatic insects. However, this study has identified major forces, such as compositional constraints and mutation pressure, which shape patterns of codon usage in mitochondrial genes in the primitive clades of insect lineages. PMID
Papadimitriou, Lamprini V.; Koutroulis, Aristeidis G.; Grillakis, Manolis G.; Tsanis, Ioannis K.
2016-05-01
Climate models project a much more substantial warming than the 2 °C target under the more probable emission scenarios, making higher-end scenarios increasingly plausible. Freshwater availability under such conditions is a key issue of concern. In this study, an ensemble of Euro-CORDEX projections under RCP8.5 is used to assess the mean and low hydrological states under +4 °C of global warming for the European region. Five major European catchments were analysed in terms of future drought climatology and the impact of +2 °C versus +4 °C global warming was investigated. The effect of bias correction of the climate model outputs and the observations used for this adjustment was also quantified. Projections indicate an intensification of the water cycle at higher levels of warming. Even for areas where the average state may not considerably be affected, low flows are expected to reduce, leading to changes in the number of dry days and thus drought climatology. The identified increasing or decreasing runoff trends are substantially intensified when moving from the +2 to the +4° of global warming. Bias correction resulted in an improved representation of the historical hydrology. It is also found that the selection of the observational data set for the application of the bias correction has an impact on the projected signal that could be of the same order of magnitude to the selection of the Global Climate Model (GCM).
Schmidt, P J; Emelko, M B; Thompson, M E
2013-05-01
Quantitative microbial risk assessment (QMRA) is a tool to evaluate the potential implications of pathogens in a water supply or other media and is of increasing interest to regulators. In the case of potentially pathogenic protozoa (e.g. Cryptosporidium oocysts and Giardia cysts), it is well known that the methods used to enumerate (oo)cysts in samples of water and other media can have low and highly variable analytical recovery. In these applications, QMRA has evolved from ignoring analytical recovery to addressing it in point-estimates of risk, and then to addressing variation of analytical recovery in Monte Carlo risk assessments. Often, variation of analytical recovery is addressed in exposure assessment by dividing concentration values that were obtained without consideration of analytical recovery by random beta-distributed recovery values. A simple mathematical proof is provided to demonstrate that this conventional approach to address non-constant analytical recovery in drinking water QMRA will lead to overestimation of mean pathogen concentrations. The bias, which can exceed an order of magnitude, is greatest when low analytical recovery values are common. A simulated dataset is analyzed using a diverse set of approaches to obtain distributions representing temporal variation in the oocyst concentration, and mean annual risk is then computed from each concentration distribution using a simple risk model. This illustrative example demonstrates that the bias associated with mishandling non-constant analytical recovery and non-detect samples can cause drinking water systems to be erroneously classified as surpassing risk thresholds.
Hydrological modeling as an evaluation tool of EURO-CORDEX RCMs and bias correction methods
Hakala, Kirsti; Seibert, Jan; Addor, Nans
2016-04-01
This research explores the impacts of climate change on catchment discharge and addresses the challenge of characterizing and communicating their uncertainties. It particularly focuses on the integrated evaluation of EURO-CORDEX regional climate model simulations, using hydrological modeling at the catchment scale. For the evaluation of the various RCMs combined with different bias correction operations there are two main approaches: 1) Separate evaluation of the statistical properties of each climate variable in terms of its statistical properties such as annual mean, seasonal variation, frequency of extreme events. This first approach is the standard way to evaluate RCM runs and bias correction methods. It also prevails by far in the literature. Here we introduce an alternative evaluation approach, which relies on hydrological modeling, 2) Combined evaluation of the different variables at the catchment scale; that is the evaluation is based on hydrological simulation results, which integrate the different variables (mainly temperature, precipitation and evaporation). Although more time demanding, this second approach has a critical advantage in that it allows a focus on the statistical properties of the climate variables which are most important for catchment-scale runoff. We rely on the semi-distributed hydrological model HBV and apply it to Swiss catchments representative of different hydrological regimes and expected responses to climate change. This research investigates both approaches, however the second approach will be discussed in greater depth as an elegant way to consider the multitude of factors relevant for hydrological modeling all at once.
Atomic force microscopy in biomedical research - Methods and protocols
Directory of Open Access Journals (Sweden)
CarloAlberto Redi
2011-11-01
Full Text Available Pier Carlo Braga and Davide Ricci are old friends not only for those researchers familiar with Atomic force microscopy (AFM but also for those beginners (like the undersigned that already enthusiastically welcomed their 2004 edition (for the same Humana press printing types of Atomic force microscopy: Biomedical methods and applications, eventhough I never had used the AFM. That book was much intended to overview the possible AFM applications for a wide range of readers so that they can be in some way stimulated toward the AFM use. In fact, the great majority of scientists is afraid both of the technology behind AFM (that is naturally thought highly demanding in term of concepts not so familiar to biologists and physicians and of the financial costs: both these two factors are conceived unapproachable by the medium range granted scientist usually not educated in terms of biophysics and electronic background....
A method for evaluating bias in global measurements of CO2 total columns from space
Directory of Open Access Journals (Sweden)
R. J. Salawitch
2011-12-01
Full Text Available We describe a method of evaluating systematic errors in measurements of total column dry-air mole fractions of CO2 (XCO2 from space, and we illustrate the method by applying it to the v2.8 Atmospheric CO2 Observations from Space retrievals of the Greenhouse Gases Observing Satellite (ACOS-GOSAT measurements over land. The approach exploits the lack of large gradients in XCO2 south of 25° S to identify large-scale offsets and other biases in the ACOS-GOSAT data with several retrieval parameters and errors in instrument calibration. We demonstrate the effectiveness of the method by comparing the ACOS-GOSAT data in the Northern Hemisphere with ground truth provided by the Total Carbon Column Observing Network (TCCON. We use the observed correlation between free-tropospheric potential temperature and XCO2 in the Northern Hemisphere to define a dynamically informed coincidence criterion between the ground-based TCCON measurements and the ACOS-GOSAT measurements. We illustrate that this approach provides larger sample sizes, hence giving a more robust comparison than one that simply uses time, latitude and longitude criteria. Our results show that the agreement with the TCCON data improves after accounting for the systematic errors, but that extrapolation to conditions found outside the region south of 25° S may be problematic (e.g., high airmasses, large surface pressure biases, M-gain, measurements made over ocean. A preliminary evaluation of the improved v2.9 ACOS-GOSAT data is also discussed.
Connelly, M. J.
2014-05-01
The slow light effect in SOAs has many applications in microwave photonics such as phase shifting and filtering. Models are needed to predict slow light in SOAs and its dependence on the bias current, optical power and modulation index. In this paper we predict the slow light characteristics of a tensile-strained SOA by using a detailed time-domain model. The model includes full band-structure based calculations of the material gain, bimolecular recombination and spontaneous emission, a carrier density rate equation and travelling wave equations for the input signal and amplified spontaneous emission. The slow light effect is caused by coherent population oscillations, whereby beating between the spectral components of an amplitude modulated lightwave causes carrier density oscillations at the beat frequency, leading to changes in the group velocity. The resulting beat signal at the SOA output after photodetection, is phase shifted relative to the SOA input beat signal. The phase shift can be adjusted by controlling the optical power and bias current. However the beat signal gain is low at low frequencies, leading to a poor beat signal output signal-to-noise ratio. If the optical input and SOA drive current are simultaneously modulated, this leads to forced population oscillations that greatly enhance the low frequency beat signal gain. The model is used to determine the improvement in gain and phase response and its dependency on the optical power, bias current and modulation index. Model predictions show good agreement with experimental trends reported in the literature.
Choosing the forcing terms in an inexact Newton method
Energy Technology Data Exchange (ETDEWEB)
Eisenstat, S.C. [Yale Univ., New Haven, CT (United States); Walker, H.F. [Utah State Univ., Logan, UT (United States)
1994-12-31
An inexact Newton method is a generalization of Newton`s method for solving F(x) = 0, F: {Re}{sup n} {r_arrow} {Re}{sup n}, in which each step reduces the norm of the local linear model of F. At the kth iteration, the norm reduction is usefully expressed by the inexact Newton condition where x{sub k} is the current approximate solution and s{sub k} is the step. In many applications, an {eta}{sub k} is first specified, and then an S{sub k} is found for which the inexact Newton condition holds. Thus {eta}{sub k} is often called a {open_quotes}forcing term{close_quotes}. In practice, the choice of the forcing terms is usually critical to the efficiency of the method and can affect robustness as well. Here, the authors outline several promising choices, discuss theoretical support for them, and compare their performance in a Newton iterative (truncated Newton) method applied to several large-scale problems.
Smith, Micholas Dean; Rao, J Srinivasa; Segelken, Elizabeth; Cruz, Luis
2015-12-28
In this work we examine the dynamics of an intrinsically disordered protein fragment of the amyloid β, the Aβ21-30, under seven commonly used molecular dynamics force fields (OPLS-AA, CHARMM27-CMAP, AMBER99, AMBER99SB, AMBER99SB-ILDN, AMBER03, and GROMOS53A6), and three water models (TIP3P, TIP4P, and SPC/E). We find that the tested force fields and water models have little effect on the measures of radii of gyration and solvent accessible surface area (SASA); however, secondary structure measures and intrapeptide hydrogen-bonding are significantly modified, with AMBER (99, 99SB, 99SB-ILDN, and 03) and CHARMM22/27 force-fields readily increasing helical content and the variety of intrapeptide hydrogen bonds. On the basis of a comparison between the population of helical and β structures found in experiments, our data suggest that force fields that suppress the formation of helical structure might be a better choice to model the Aβ21-30 peptide. PMID:26629886
Bannerman, J A; Costamagna, A C; McCornack, B P; Ragsdale, D W
2015-06-01
Generalist natural enemies play an important role in controlling soybean aphid, Aphis glycines (Hemiptera: Aphididae), in North America. Several sampling methods are used to monitor natural enemy populations in soybean, but there has been little work investigating their relative bias, precision, and efficiency. We compare five sampling methods: quadrats, whole-plant counts, sweep-netting, walking transects, and yellow sticky cards to determine the most practical methods for sampling the three most prominent species, which included Harmonia axyridis (Pallas), Coccinella septempunctata L. (Coleoptera: Coccinellidae), and Orius insidiosus (Say) (Hemiptera: Anthocoridae). We show an important time by sampling method interaction indicated by diverging community similarities within and between sampling methods as the growing season progressed. Similarly, correlations between sampling methods for the three most abundant species over multiple time periods indicated differences in relative bias between sampling methods and suggests that bias is not consistent throughout the growing season, particularly for sticky cards and whole-plant samples. Furthermore, we show that sticky cards produce strongly biased capture rates relative to the other four sampling methods. Precision and efficiency differed between sampling methods and sticky cards produced the most precise (but highly biased) results for adult natural enemies, while walking transects and whole-plant counts were the most efficient methods for detecting coccinellids and O. insidiosus, respectively. Based on bias, precision, and efficiency considerations, the most practical sampling methods for monitoring in soybean include walking transects for coccinellid detection and whole-plant counts for detection of small predators like O. insidiosus. Sweep-netting and quadrat samples are also useful for some applications, when efficiency is not paramount. PMID:26470267
Bannerman, J A; Costamagna, A C; McCornack, B P; Ragsdale, D W
2015-06-01
Generalist natural enemies play an important role in controlling soybean aphid, Aphis glycines (Hemiptera: Aphididae), in North America. Several sampling methods are used to monitor natural enemy populations in soybean, but there has been little work investigating their relative bias, precision, and efficiency. We compare five sampling methods: quadrats, whole-plant counts, sweep-netting, walking transects, and yellow sticky cards to determine the most practical methods for sampling the three most prominent species, which included Harmonia axyridis (Pallas), Coccinella septempunctata L. (Coleoptera: Coccinellidae), and Orius insidiosus (Say) (Hemiptera: Anthocoridae). We show an important time by sampling method interaction indicated by diverging community similarities within and between sampling methods as the growing season progressed. Similarly, correlations between sampling methods for the three most abundant species over multiple time periods indicated differences in relative bias between sampling methods and suggests that bias is not consistent throughout the growing season, particularly for sticky cards and whole-plant samples. Furthermore, we show that sticky cards produce strongly biased capture rates relative to the other four sampling methods. Precision and efficiency differed between sampling methods and sticky cards produced the most precise (but highly biased) results for adult natural enemies, while walking transects and whole-plant counts were the most efficient methods for detecting coccinellids and O. insidiosus, respectively. Based on bias, precision, and efficiency considerations, the most practical sampling methods for monitoring in soybean include walking transects for coccinellid detection and whole-plant counts for detection of small predators like O. insidiosus. Sweep-netting and quadrat samples are also useful for some applications, when efficiency is not paramount.
25 CFR 170.605 - When may BIA use force account methods in the IRR Program?
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false When may BIA use force account methods in the IRR Program... § 170.605 When may BIA use force account methods in the IRR Program? BIA may use force account methods... before using a force account under this situation. The applicable FAR and Federal law apply to BIA...
Numerical Method for Wave Forces Acting on Partially Perforated Caisson
Institute of Scientific and Technical Information of China (English)
姜峰; 唐晓成; 金钊; 张莉; 陈洪洲
2015-01-01
The perforated caisson is widely applied to practical engineering because of its great advantages in effectively wave energy consumption and cost reduction. The attentions of many scientists were paid to the fluid–structure interaction between wave and perforated caisson studies, but until now, most concerns have been put on theoretical analysis and experimental model set up. In this paper, interaction between the wave and the partial perforated caisson in a 2D numerical wave flume is investigated by means of the renewed SPH algorithm, and the mathematical equations are in the form of SPH numerical approximation based on Navier–Stokes equations. The validity of the SPH mathematical method is examined and the simulated results are compared with the results of theoretical models, meanwhile the complex hydrodynamic characteristics when the water particles flow in or out of a wave absorbing chamber are analyzed and the wave pressure distribution of the perforated caisson is also addressed here. The relationship between the ratio of total horizontal force acting on caisson under regular waves and its influence factors is examined. The data show that the numerical calculation of the ratio of total horizontal force meets the empirical regression equation very well. The simulations of SPH about the wave nonlinearity and breaking are briefly depicted in the paper, suggesting that the advantages and great potentiality of the SPH method is significant compared with traditional methods.
Stein's method and the zero bias transformation with application to simple random sampling
Goldstein, Larry; Reinert, Gesine
1997-01-01
Let $W$ be a random variable with mean zero and variance $\\sigma^2$. The distribution of a variate $W^*$, satisfying $EWf(W)=\\sigma ^2 Ef'(W^*)$ for smooth functions $f$, exists uniquely and defines the zero bias transformation on the distribution of $W$. The zero bias transformation shares many interesting properties with the well known size bias transformation for non-negative variables, but is applied to variables taking on both positive and negative values. The transformation can also be ...
Kong, Xiangdong; Ba, Kaixian; Yu, Bin; Cao, Yuan; Zhu, Qixin; Zhao, Hualong
2016-05-01
Each joint of hydraulic drive quadruped robot is driven by the hydraulic drive unit (HDU), and the contacting between the robot foot end and the ground is complex and variable, which increases the difficulty of force control inevitably. In the recent years, although many scholars researched some control methods such as disturbance rejection control, parameter self-adaptive control, impedance control and so on, to improve the force control performance of HDU, the robustness of the force control still needs improving. Therefore, how to simulate the complex and variable load characteristics of the environment structure and how to ensure HDU having excellent force control performance with the complex and variable load characteristics are key issues to be solved in this paper. The force control system mathematic model of HDU is established by the mechanism modeling method, and the theoretical models of a novel force control compensation method and a load characteristics simulation method under different environment structures are derived, considering the dynamic characteristics of the load stiffness and the load damping under different environment structures. Then, simulation effects of the variable load stiffness and load damping under the step and sinusoidal load force are analyzed experimentally on the HDU force control performance test platform, which provides the foundation for the force control compensation experiment research. In addition, the optimized PID control parameters are designed to make the HDU have better force control performance with suitable load stiffness and load damping, under which the force control compensation method is introduced, and the robustness of the force control system with several constant load characteristics and the variable load characteristics respectively are comparatively analyzed by experiment. The research results indicate that if the load characteristics are known, the force control compensation method presented in this
Directory of Open Access Journals (Sweden)
Stephanie M Willerth
Full Text Available BACKGROUND: With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (HIV, and an additional 4.1 million people becoming infected each year, it is important to understand how this virus mutates and develops resistance in order to design successful therapies. METHODOLOGY/PRINCIPAL FINDINGS: We report a novel experimental method for amplifying full-length HIV genomes without the use of sequence-specific primers for high throughput DNA sequencing, followed by assembly of full length viral genome sequences from the resulting large dataset. Illumina was chosen for sequencing due to its ability to provide greater coverage of the HIV genome compared to prior methods, allowing for more comprehensive characterization of the heterogeneity present in the HIV samples analyzed. Our novel amplification method in combination with Illumina sequencing was used to analyze two HIV populations: a homogenous HIV population based on the canonical NL4-3 strain and a heterogeneous viral population obtained from a HIV patient's infected T cells. In addition, the resulting sequence was analyzed using a new computational approach to obtain a consensus sequence and several metrics of diversity. SIGNIFICANCE: This study demonstrates how a lower bias amplification method in combination with next generation DNA sequencing provides in-depth, complete coverage of the HIV genome, enabling a stronger characterization of the quasispecies present in a clinically relevant HIV population as well as future study of how HIV mutates in response to a selective pressure.
Evaluation of Bias Correction Method for Satellite-Based Rainfall Data
Directory of Open Access Journals (Sweden)
Haris Akram Bhatti
2016-06-01
Full Text Available With the advances in remote sensing technology, satellite-based rainfall estimates are gaining attraction in the field of hydrology, particularly in rainfall-runoff modeling. Since estimates are affected by errors correction is required. In this study, we tested the high resolution National Oceanic and Atmospheric Administration’s (NOAA Climate Prediction Centre (CPC morphing technique (CMORPH satellite rainfall product (CMORPH in the Gilgel Abbey catchment, Ethiopia. CMORPH data at 8 km-30 min resolution is aggregated to daily to match in-situ observations for the period 2003–2010. Study objectives are to assess bias of the satellite estimates, to identify optimum window size for application of bias correction and to test effectiveness of bias correction. Bias correction factors are calculated for moving window (MW sizes and for sequential windows (SW’s of 3, 5, 7, 9, …, 31 days with the aim to assess error distribution between the in-situ observations and CMORPH estimates. We tested forward, central and backward window (FW, CW and BW schemes to assess the effect of time integration on accumulated rainfall. Accuracy of cumulative rainfall depth is assessed by Root Mean Squared Error (RMSE. To systematically correct all CMORPH estimates, station based bias factors are spatially interpolated to yield a bias factor map. Reliability of interpolation is assessed by cross validation. The uncorrected CMORPH rainfall images are multiplied by the interpolated bias map to result in bias corrected CMORPH estimates. Findings are evaluated by RMSE, correlation coefficient (r and standard deviation (SD. Results showed existence of bias in the CMORPH rainfall. It is found that the 7 days SW approach performs best for bias correction of CMORPH rainfall. The outcome of this study showed the efficiency of our bias correction approach.
Investigation of multi-junction solar cells using electrostatic force microscopy methods
International Nuclear Information System (INIS)
Multi-junction III–V solar cells are designed to have a much broader absorption of the solar spectrum than Si-based or single junctions, thus yield the highest conversion. The conversion efficiency can be further scaled with sun concentration. The ability of high conversion efficiencies makes multi-junction prime candidates for fine-tuning explorations aimed at getting closer to the theoretical efficiencies. In this paper, we report on electrostatic force microscopy (EFM) measurements of the built-in potential of multi-junction III–V semiconductor-based solar cells. Kelvin probe force microscopy (KPFM) was employed to qualitatively study the width and electrical properties of individual junctions, i.e., built-in potential, activity, and thickness of the p–n junctions. In addition, the voltage drops across individual solar cell p–n junctions were measured using Kelvin probe microscopy under various operation conditions: dark; illuminated; short-circuit; and biased. We present a method which enables the measurement of a working structure, while focusing on the electrical characteristics of an individual junction by virtue of selecting the spectral range of the illumination used. We show that these pragmatic studies can provide a feedback to improve photovoltaic device design, particularly of operation under a current mismatched situation. This new analysis technique offers additional insights into behavior of the multi-junction solar cell and shows promise for further progress in this field. - Highlights: • We explore the electronic structure of III–V based high efficiency solar cells. • Qualitative study of the solar cell operation characteristics is presented. • Quantitative study of the electrostatic landscape of operational high efficiency devices is presented. • Precise identification of the epitaxially grown p–n and tunnel junctions in the multi-junction solar cell. • Influence of illumination conditions and cell biasing on each p
Investigation of multi-junction solar cells using electrostatic force microscopy methods
Energy Technology Data Exchange (ETDEWEB)
Moczała, M., E-mail: magdalena.moczala@pwr.wroc.pl [Wrocław University of Technology, Faculty of Microsystem Electronics and Photonics, Division of Metrology of Micro- and Nanostructures, ul. Z. Janiszewskiego 11/17, 50-372 Wrocław (Poland); Sosa, N.; Topol, A. [IBM Thomas J. Watson Research Center, P.O. Box 218, Yorktown Heights, NY 10598 (United States); Gotszalk, T. [Wrocław University of Technology, Faculty of Microsystem Electronics and Photonics, Division of Metrology of Micro- and Nanostructures, ul. Z. Janiszewskiego 11/17, 50-372 Wrocław (Poland)
2014-06-01
Multi-junction III–V solar cells are designed to have a much broader absorption of the solar spectrum than Si-based or single junctions, thus yield the highest conversion. The conversion efficiency can be further scaled with sun concentration. The ability of high conversion efficiencies makes multi-junction prime candidates for fine-tuning explorations aimed at getting closer to the theoretical efficiencies. In this paper, we report on electrostatic force microscopy (EFM) measurements of the built-in potential of multi-junction III–V semiconductor-based solar cells. Kelvin probe force microscopy (KPFM) was employed to qualitatively study the width and electrical properties of individual junctions, i.e., built-in potential, activity, and thickness of the p–n junctions. In addition, the voltage drops across individual solar cell p–n junctions were measured using Kelvin probe microscopy under various operation conditions: dark; illuminated; short-circuit; and biased. We present a method which enables the measurement of a working structure, while focusing on the electrical characteristics of an individual junction by virtue of selecting the spectral range of the illumination used. We show that these pragmatic studies can provide a feedback to improve photovoltaic device design, particularly of operation under a current mismatched situation. This new analysis technique offers additional insights into behavior of the multi-junction solar cell and shows promise for further progress in this field. - Highlights: • We explore the electronic structure of III–V based high efficiency solar cells. • Qualitative study of the solar cell operation characteristics is presented. • Quantitative study of the electrostatic landscape of operational high efficiency devices is presented. • Precise identification of the epitaxially grown p–n and tunnel junctions in the multi-junction solar cell. • Influence of illumination conditions and cell biasing on each p
Rus, David L.; Patton, Charles J.; Mueller, David K.; Crawford, Charles G.
2013-01-01
The characterization of total-nitrogen (TN) concentrations is an important component of many surface-water-quality programs. However, three widely used methods for the determination of total nitrogen—(1) derived from the alkaline-persulfate digestion of whole-water samples (TN-A); (2) calculated as the sum of total Kjeldahl nitrogen and dissolved nitrate plus nitrite (TN-K); and (3) calculated as the sum of dissolved nitrogen and particulate nitrogen (TN-C)—all include inherent limitations. A digestion process is intended to convert multiple species of nitrogen that are present in the sample into one measureable species, but this process may introduce bias. TN-A results can be negatively biased in the presence of suspended sediment, and TN-K data can be positively biased in the presence of elevated nitrate because some nitrate is reduced to ammonia and is therefore counted twice in the computation of total nitrogen. Furthermore, TN-C may not be subject to bias but is comparatively imprecise. In this study, the effects of suspended-sediment and nitrate concentrations on the performance of these TN methods were assessed using synthetic samples developed in a laboratory as well as a series of stream samples. A 2007 laboratory experiment measured TN-A and TN-K in nutrient-fortified solutions that had been mixed with varying amounts of sediment-reference materials. This experiment identified a connection between suspended sediment and negative bias in TN-A and detected positive bias in TN-K in the presence of elevated nitrate. A 2009–10 synoptic-field study used samples from 77 stream-sampling sites to confirm that these biases were present in the field samples and evaluated the precision and bias of TN methods. The precision of TN-C and TN-K depended on the precision and relative amounts of the TN-component species used in their respective TN computations. Particulate nitrogen had an average variability (as determined by the relative standard deviation) of 13
Gap engineering using Hellmann-Feynmann forces: method and applications
Prasai, Kiran; Biawas, Parthapratim; Drabold, D. A.
Materials with optimized band gap are needed in many specialized applications. In this talk, we demonstrate that Hellmann-Feynman forces associated with the gap states can be used to find atomic coordinates that yield desired electronic density of states. Using tight-binding models, we show that this approach may be used to arrive at electronically designed models of amorphous silicon and carbon. We provide a simple recipe to include a priori electronic information in the formation of computer models of materials, and prove that this information may have profound structural consequences. We'll briefly discuss implementation of the method in ab-initio molecular dynamics simulations and highlight the latest feats of the method ranging from modeling amorphous semi-conducting materials to understanding the structure and properties of memory materials. K. Prasai, P. Biswas, and D. A. Drabold, Scientific reports, 5 (2015).
DEFF Research Database (Denmark)
Thorson, James T.; Kristensen, Kasper
2016-01-01
-method to a spatial regression model when estimating an index of population abundance, and compare results with an alternative bias-correction algorithm that involves Markov-chain Monte Carlo sampling. This example shows that the epsilon-method leads to a biologically significant difference in estimates of average...
Thompson, Michael; Owen, Linda; Wilkinson, Kate; Wood, Roger; Damant, Andrew
2004-12-01
Bias between the Dumas and the Kjeldahl methods for the determination of protein nitrogen in food was studied by conducting an interlaboratory study involving 40 laboratories and 20 different test materials. Biases were found to be small and statistically significant only for the chicken test materials, where a bias of 0.020±0.004% m/m was detected.
Robust numerical methods for conservation laws using a biased averaging procedure
Choi, Hwajeong
In this thesis, we introduce a new biased averaging procedure (BAP) and use it in developing high resolution schemes for conservation laws. Systems of conservation laws arise in variety of physical problems, such as the Euler equation of compressible flows, magnetohydrodynamics, multicomponent flows, the blast waves and the flow of glaciers. Many modern shock capturing schemes are based on solution reconstructions by high order polynomial interpolations, and time evolution by the solutions of Riemann problems. Due to the existence of discontinuities in the solution, the interpolating polynomial has to be carefully constructed to avoid possible oscillations near discontinuities. The BAP is a more general and simpler way to approximate higher order derivatives of given data without introducing oscillations, compared to limiters and the essentially non-oscillatory interpolations. For the solution of a system of conservation laws, we present a finite volume method which employs a flux splitting and uses componentwise reconstruction of the upwind fluxes. A high order piecewise polynomial constructed by using BAP is used to approximate the component of upwind fluxes. This scheme does not require characteristic decomposition nor Riemann solver, offering easy implementation and a relatively small computational cost. More importantly, the BAP is naturally extended for unstructured grids and it will be demonstrated through a cell-centered finite volume method, along with adaptive mesh refinement. A number of numerical experiments from various applications demonstrates the robustness and the accuracy of this approach, and show the potential of this approach for other practical applications.
Leyrat, Clémence; Caille, Agnès; Donner, Allan; Giraudeau, Bruno
2014-09-10
Despite randomization, selection bias may occur in cluster randomized trials. Classical multivariable regression usually allows for adjusting treatment effect estimates with unbalanced covariates. However, for binary outcomes with low incidence, such a method may fail because of separation problems. This simulation study focused on the performance of propensity score (PS)-based methods to estimate relative risks from cluster randomized trials with binary outcomes with low incidence. The results suggested that among the different approaches used (multivariable regression, direct adjustment on PS, inverse weighting on PS, and stratification on PS), only direct adjustment on the PS fully corrected the bias and moreover had the best statistical properties. PMID:24771662
Force-Directed Method in Mirror Frames for Graph Drawing
Jing Lee; Ching-Hsing Pei
2010-01-01
The most widely used algorithms for graph drawing are force-directed algorithms. We should modify a hybrid force model that is coupling a traditional spring force model and a novel repulsive force model will be proposed to solve the graph drawing problems in 2-D space. Especially, regular triangle drawing frame can be applied to binary tree drawing problems that on an important contribution to computer science. And apply circle drawing frame to normal graph drawing problems, we get satisfacto...
Kalashnikova, A. M.; Kozub, V. I.
2016-02-01
Experimentally observed ultrafast all-optical magnetization reversal in ferrimagnetic metals and heterostructures based on antiferromagnetically coupled ferromagnetic d - and f -metallic layers relies on intricate energy and angular momentum flow between electrons, phonons, and spins. Here we treat the problem of angular momentum transfer in the course of ultrafast laser-induced dynamics in a ferrimagnetic metallic system using microscopical approach based on the system of rate equations. We show that the magnetization reversal is supported by a coupling of d and f subsystems to delocalized s or p electrons. The latter can transfer spin between the two subsystems in an incoherent way owing to the (s ;p )-(d ;f ) exchange scattering. Since the effect of the external excitation in this process is reduced to the transient heating of the mobile electron subsystem, we also discuss the possibility to trigger the magnetization reversal by applying a voltage bias pulse to antiferromagnetically coupled metallic ferromagnetic layers embedded in point contact or tunneling structures. We argue that such devices allow controlling reversal with high accuracy. We also suggest using the anomalous Hall effect to register the reversal, thus playing a role of reading probes.
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
Effect of relative humidity on the surface adhesion force of several inorganic crystals of mica, CaF2 and KCl was studied by atomic force microscopy (AFM). The results showed that the magnitude of surface adhesion force is mainly dependent on the surface free energy of the adsorbed liquid film, but almost independent of the thickness of the film. Furthermore, the deliquescence on the crystal surface was investigated, which demonstrated the capability of the force spectrum method to monitor changes in ionic concentrations of adsorbed liquid film in real-time.
Novak, Janja; Jeremy D Bailoo; Melotti, Luca; Rommen, Jonas; Würbel, Hanno
2015-01-01
Behavioural tests to assess affective states are widely used in human research and have recently been extended to animals. These tests assume that affective state influences cognitive processing, and that animals in a negative affective state interpret ambiguous information as expecting a negative outcome (displaying a negative cognitive bias). Most of these tests however, require long discrimination training. The aim of the study was to validate an exploration based cognitive bias test, usin...
Directory of Open Access Journals (Sweden)
G. H. Fang
2014-11-01
Full Text Available Water resources are essential to the ecosystem and social economy in the desert and oasis of the arid Tarim River Basin, Northwest China, and expected to be vulnerable to climate change. Regional Climate Models (RCM have been proved to provide more reliable results for regional impact study of climate change (e.g. on water resources than GCM models. However, it is still necessary to apply bias correction before they are used for water resources research due to often considerable biases. In this paper, after a sensitivity analysis on input meteorological variables based on Sobol' method, we compared five precipitation correction methods and three temperature correction methods to the output of a RCM model with its application to the Kaidu River Basin, one of the headwaters of the Tarim River Basin. Precipitation correction methods include Linear Scaling (LS, LOCal Intensity scaling (LOCI, Power Transformation (PT, Distribution Mapping (DM and Quantile Mapping (QM; and temperature correction methods include LS, VARIance scaling (VARI and DM. These corrected precipitation and temperature were compared to the observed meteorological data, and then their impacts on streamflow were also compared by driving a distributed hydrologic model. The results show: (1 precipitation, temperature, solar radiation are sensitivity to streamflow while relative humidity and wind speed are not, (2 raw RCM simulations are heavily biased from observed meteorological data, which results in biases in the simulated streamflows, and all bias correction methods effectively improved theses simulations, (3 for precipitation, PT and QM methods performed equally best in correcting the frequency-based indices (e.g. SD, percentile values while LOCI method performed best in terms of the time series based indices (e.g. Nash–Sutcliffe coefficient, R2, (4 for temperature, all bias correction methods performed equally well in correcting raw temperature. (5 For simulated streamflow
Ertefaie, Ashkan; Small, Dylan; Flory, James; Hennessy, Sean
2016-05-01
Instrumental variable (IV) methods are widely used to adjust for the bias in estimating treatment effects caused by unmeasured confounders in observational studies. It is common that a comparison between two treatments is focused on and that only subjects receiving one of these two treatments are considered in the analysis even though more than two treatments are available. In this paper, we provide empirical and theoretical evidence that the IV methods may result in biased treatment effects if applied on a data set in which subjects are preselected based on their received treatments. We frame this as a selection bias problem and propose a procedure that identifies the treatment effect of interest as a function of a vector of sensitivity parameters. We also list assumptions under which analyzing the preselected data does not lead to a biased treatment effect estimate. The performance of the proposed method is examined using simulation studies. We applied our method on The Health Improvement Network (THIN) database to estimate the comparative effect of metformin and sulfonylureas on weight gain among diabetic patients. PMID:27227722
Energy Technology Data Exchange (ETDEWEB)
Ali, Fazlat; Gunji, Michiharu; Yang, Sung-Chae; Suzuki, Tsuneo; Suematsu, Hisayuki; Jiang, Weihua; Yatsui, Kiyoshi [Nagaoka Univ. of Technology, Extreme Energy-Density Research Inst., Nagaoka, Niigata (Japan)
2002-06-01
The deposition of polycrystalline silicon thin films has been tried by a pulsed ion-beam evaporation method, where high crystallinity and deposition rate have been achieved without heating the substrate. The crystallinity and the deposition rate were improved by applying bias voltage to the substrate, where instantaneous substrate heating might have occurred by ion-bombardment. (author)
International Nuclear Information System (INIS)
The deposition of polycrystalline silicon thin films has been tried by a pulsed ion-beam evaporation method, where high crystallinity and deposition rate have been achieved without heating the substrate. The crystallinity and the deposition rate were improved by applying bias voltage to the substrate, where instantaneous substrate heating might have occurred by ion-bombardment. (author)
Force-Directed Method in Mirror Frames for Graph Drawing
Directory of Open Access Journals (Sweden)
Jing Lee
2010-11-01
Full Text Available The most widely used algorithms for graph drawing are force-directed algorithms. We should modify a hybrid force model that is coupling a traditional spring force model and a novel repulsive force model will be proposed to solve the graph drawing problems in 2-D space. Especially, regular triangle drawing frame can be applied to binary tree drawing problems that on an important contribution to computer science. And apply circle drawing frame to normal graph drawing problems, we get satisfactory and aesthetic criteria graphics.
Indian Academy of Sciences (India)
G Sasibhushana Rao
2007-10-01
The positional accuracy of the Global Positioning System (GPS)is limited due to several error sources.The major error is ionosphere.By augmenting the GPS,the Category I (CAT I)Precision Approach (PA)requirements can be achieved.The Space-Based Augmentation System (SBAS)in India is known as GPS Aided Geo Augmented Navigation (GAGAN).One of the prominent errors in GAGAN that limits the positional accuracy is instrumental biases.Calibration of these biases is particularly important in achieving the CAT I PA landings.In this paper,a new algorithm is proposed to estimate the instrumental biases by modelling the TEC using 4th order polynomial.The algorithm uses values corresponding to a single station for one month period and the results conﬁrm the validity of the algorithm.The experimental results indicate that the estimation precision of the satellite-plus-receiver instrumental bias is of the order of ± 0.17 nsec.The observed mean bias error is of the order − 3.638 nsec and − 4.71 nsec for satellite 1 and 31 respectively.It is found that results are consistent over the period.
Amplified RNA degradation in T7-amplification methods results in biased microarray hybridizations
Directory of Open Access Journals (Sweden)
Ivell Richard
2003-11-01
Full Text Available Abstract Background The amplification of RNA with the T7-System is a widely used technique for obtaining increased amounts of RNA starting from limited material. The amplified RNA (aRNA can subsequently be used for microarray hybridizations, warranting sufficient signal for image analysis. We describe here an amplification-time dependent degradation of aRNA in prolonged standard T7 amplification protocols, that results in lower average size aRNA and decreased yields. Results A time-dependent degradation of amplified RNA (aRNA could be observed when using the classical "Eberwine" T7-Amplification method. When the amplification was conducted for more than 4 hours, the resulting aRNA showed a significantly smaller size distribution on gel electrophoresis and a concomitant reduction of aRNA yield. The degradation of aRNA could be correlated to the presence of the T7 RNA Polymerase in the amplification cocktail. The aRNA degradation resulted in a strong bias in microarray hybridizations with a high coefficient of variation and a significant reduction of signals of certain transcripts, that seem to be susceptible to this RNA degrading activity. The time-dependent degradation of these transcripts was verified by a real-time PCR approach. Conclusions It is important to perform amplifications not longer than 4 hours as there is a characteristic 'quality vs. yield' situation for longer amplification times. When conducting microarray hybridizations it is important not to compare results obtained with aRNA from different amplification times.
Fang, G. H.; Yang, J.; Chen, Y. N.; Zammit, C.
2015-06-01
Water resources are essential to the ecosystem and social economy in the desert and oasis of the arid Tarim River basin, northwestern China, and expected to be vulnerable to climate change. It has been demonstrated that regional climate models (RCMs) provide more reliable results for a regional impact study of climate change (e.g., on water resources) than general circulation models (GCMs). However, due to their considerable bias it is still necessary to apply bias correction before they are used for water resources research. In this paper, after a sensitivity analysis on input meteorological variables based on the Sobol' method, we compared five precipitation correction methods and three temperature correction methods in downscaling RCM simulations applied over the Kaidu River basin, one of the headwaters of the Tarim River basin. Precipitation correction methods applied include linear scaling (LS), local intensity scaling (LOCI), power transformation (PT), distribution mapping (DM) and quantile mapping (QM), while temperature correction methods are LS, variance scaling (VARI) and DM. The corrected precipitation and temperature were compared to the observed meteorological data, prior to being used as meteorological inputs of a distributed hydrologic model to study their impacts on streamflow. The results show (1) streamflows are sensitive to precipitation, temperature and solar radiation but not to relative humidity and wind speed; (2) raw RCM simulations are heavily biased from observed meteorological data, and its use for streamflow simulations results in large biases from observed streamflow, and all bias correction methods effectively improved these simulations; (3) for precipitation, PT and QM methods performed equally best in correcting the frequency-based indices (e.g., standard deviation, percentile values) while the LOCI method performed best in terms of the time-series-based indices (e.g., Nash-Sutcliffe coefficient, R2); (4) for temperature, all
Directory of Open Access Journals (Sweden)
Katharina Kranzer
Full Text Available BACKGROUND: Survival analysis using time-updated CD4+ counts during antiretroviral therapy is frequently employed to determine risk of clinical events. The time-point when the CD4+ count is assumed to change potentially biases effect estimates but methods used to estimate this are infrequently reported. METHODS: This study examined the effect of three different estimation methods: assuming i a constant CD4+ count from date of measurement until the date of next measurement, ii a constant CD4+ count from the midpoint of the preceding interval until the midpoint of the subsequent interval and iii a linear interpolation between consecutive CD4+ measurements to provide additional midpoint measurements. Person-time, tuberculosis rates and hazard ratios by CD4+ stratum were compared using all available CD4+ counts (measurement frequency 1-3 months and 6 monthly measurements from a clinical cohort. Simulated data were used to compare the extent of bias introduced by these methods. RESULTS: The midpoint method gave the closest fit to person-time spent with low CD4+ counts and for hazard ratios for outcomes both in the clinical dataset and the simulated data. CONCLUSION: The midpoint method presents a simple option to reduce bias in time-updated CD4+ analysis, particularly at low CD4 cell counts and rapidly increasing counts after ART initiation.
Does Ignoring Multi-Destination Trips in the Travel Cost Method Cause a Systematic Downward Bias?
Kuosmanen, T.K.; Nillesen, E.E.M.; Wesseler, J.H.H.
2003-01-01
In theory, treating the multi-destination trips (MDTs) as single-destination trips (SDT) does not necessarily lead to biased results, because negative effect of price increase may be offset by the shift of the estimated demand curve. However, in our empirical application of the TCM zonal model to the valuation of the economic benefits of the Bellenden Kerr National Park in Australia we find (statistically significant) evidence that ignoring the MDTs leads to a dramatic overestimation of the c...
Does ignoring multidestination trips in the travel cost method cause a systematic bias?
Kuosmanen, Timo; Nillesen, Eleonora; Wesseler, Justus
2004-01-01
The present paper demonstrates that treating multidestination trips (MDT) as single‐destination trips does not involve any systematic upward or downward bias in consumer surplus (CS) estimates because the direct negative effect of a price increase (treating MDT as a single‐destination trip) is offset by a shift in the estimated demand curve. Still, ignoring MDT can greatly underestimate or overestimate the CS. In addition, we demonstrate that there is a sound theoretical basis for using prefe...
Novak, Janja; Bailoo, Jeremy Davidson; Melotti, Luca; Rommen, Jonas; Würbel, Hanno
2015-01-01
Behavioural tests to assess affective states are widely used in human research and have recently been extended to animals. These tests assume that affective state influences cognitive processing, and that animals in a negative affective state interpret ambiguous information as expecting a negative outcome (displaying a negative cognitive bias). Most of these tests however, require long discrimination training. The aim of the study was to validate an exploration based cognitive ...
Nakano, Katsushi; Suzuki, Yoshihiko
1999-04-01
For inspection of high aspect ratio structures like narrow semiconductor trenches, a thin membrane probe and a new force detection method have been proposed. Instead of conventional conical and pyramidal tips, a thin silicon nitride cantilever was set up vertically, and its edge was used as a tip. The membrane probe named as twist-probe (TP) was oscillated in the twisting resonance to detect a force from both vertical and lateral directions. About 100 μm long, 0.7 μm thick TP was fabricated as a trial. Amplitude versus distance curve measurements showed that the TP has a high spacing change sensitivity between the tip and a sample in both vertical and lateral directions. A trench cross-section imaging was demonstrated successfully with a TP and the twist resonant force detection method.
Force measuring valve assemblies, systems including such valve assemblies and related methods
DeWall, Kevin George; Garcia, Humberto Enrique; McKellar, Michael George
2012-04-17
Methods of evaluating a fluid condition may include stroking a valve member and measuring a force acting on the valve member during the stroke. Methods of evaluating a fluid condition may include measuring a force acting on a valve member in the presence of fluid flow over a period of time and evaluating at least one of the frequency of changes in the measured force over the period of time and the magnitude of the changes in the measured force over the period of time to identify the presence of an anomaly in a fluid flow and, optionally, its estimated location. Methods of evaluating a valve condition may include directing a fluid flow through a valve while stroking a valve member, measuring a force acting on the valve member during the stroke, and comparing the measured force to a reference force. Valve assemblies and related systems are also disclosed.
Systems and methods of detecting force and stress using tetrapod nanocrystal
Choi, Charina L.; Koski, Kristie J.; Sivasankar, Sanjeevi; Alivisatos, A. Paul
2013-08-20
Systems and methods of detecting force on the nanoscale including methods for detecting force using a tetrapod nanocrystal by exposing the tetrapod nanocrystal to light, which produces a luminescent response by the tetrapod nanocrystal. The method continues with detecting a difference in the luminescent response by the tetrapod nanocrystal relative to a base luminescent response that indicates a force between a first and second medium or stresses or strains experienced within a material. Such systems and methods find use with biological systems to measure forces in biological events or interactions.
Institute of Scientific and Technical Information of China (English)
刘宇航; 陈志勇; 张嵘
2013-01-01
由于微机电系统(MEMS)陀螺通常采用微加工工艺生产制造,因此总是受微加工过程带来的的各种精度缺陷影响.对于MEMS陀螺,其零位输出误差因受环境因素影响而无法保持稳定,随时间表现出漂移特性,这种特性严重限制了MEMS陀螺在更高精度应用中的可用性.该文研究了一种改善MEMS陀螺零位误差温度稳定性的方法.通过分析陀螺运动特性及主要误差源,阐明陀螺驱动力对检测方向的耦合作用是零偏误差同相分量产生并随温度漂移的主要原因之一.为抑制陀螺驱动力耦合作用,提出对陀螺检测轴施加补偿静电力的方法.温度试验结果表明:施加补偿作用后,陀螺零偏误差同相分量的温度稳定性在12～60℃范围内提高了3倍以上.%Micro electro mechanical system (MEMS) gyroscopes can be manufactured using micro-machining procedures,but they are all subject to unavoidable defects related to the fabrication processes.The zero-rate output (ZRO) of a MEMS gyroscope is known to vary with the environment which severely restricts high-precision applications.This paper presents a method to improve MEMS gyroscope thermal stability during temperature variations.Analysis of the gyro's error sources and fundamental dynamics show that the coupling of driving forces has a crucial effect on the in phase ZRO and also contributes to the instabilities of the gyro's bias.The coupling of the gyro driving forces can be suppressed by electrostatic force compensation applied to the sensing axis with temperature tests showing that the gyro bias is three times more stable after compensation for temperatures of 12 ～ 60℃.
International Nuclear Information System (INIS)
We demonstrate the fabrication of thin films of ionic liquid (IL), 1-butyl-3-methyl-imidazolium tetrafluoborate, by nano-inkjet printing method using an atomic force microscope (AFM) cantilever. The IL filled in a pyramidal hollow of the AFM cantilever tip was extracted from an aperture at the bottom of the hollow and deposited onto a Pt substrate when the bias voltage was applied between the cantilever and the substrate. We succeeded in fabricating IL thin films with a thickness of 4 nm. The areas and thicknesses of IL thin films were controlled by the fabrication conditions in this method, which is also useful for the investigations of nanometer-scale properties of ionic liquid.
Assigning a Price to Radiative Forcing: Methods, Results, and Implications
Lutz, D. A.; Howarth, R. B.
2015-12-01
Climate change mitigation frameworks have increasingly begun to include components that involve active management of the land surface. Predominantly, these programs focus on the sequestration of greenhouse gasses in vegetation and soils, generating offset credits for projects which demonstrate considerable storage. However, it is widely known that biogeophysical interactions between the land surface and the atmosphere, such as latent and sensible heat flux, albedo radiative forcing, and surface roughness, can in many cases outweigh the influence of greenhouse gas storage on global and local climate. Surface albedo, in particular, has attracted attention in the context of these frameworks because it has been shown to influence the overall climate benefits of high-latitude forest growth through tradeoffs between carbon sequestration and radiative forcing from seasonal snow cover albedo. Here we review a methodology for pricing albedo-related radiative forcing through the use of an integrated assessment model, present the results under several emissions and social preference scenarios, and describe the implications that this pricing methodology may have on forest land management in the Northeastern United States. Additionally, we investigate the consequences of projected decreased winter precipitation on the net climate benefits of snow albedo throughout the state of New Hampshire, USA.
Tensile force correction calculation method for prestressed construction of tension structures
Institute of Scientific and Technical Information of China (English)
Xin ZHUO; Guo-fa ZHANG; Koichiro ISHIKAWA; Dao-an LOU
2008-01-01
Factors such as errors during the fabrication or construction of structural components and errors of calculation assumption or calculation methods,are very likely to cause serious deviation of many strings'actual prestressing forces from the designed values during tension structure construction or service period,and further to threaten the safety and reliability of the structure.Aiming at relatively large errors of the prestressing force of strings in a tension structure construction or service period,this paper proposes a new finite element method(FEM),the"tensile force correction calculation method".Based on the measured prestressing forces of the strings,this new method applies the structure from the zero prestressing force status approach to the measured prestressing force status for the first phase,and from the measured prestressing force status approach to the designed prestressing force status for the second phase.The construction tensile force correction value for each string can be obtained by multi-iteration with FEM.Using the results of calculation,the strings'tensile force correction by group and in batch will be methodic,simple and accurate.This new calculation method Can be applied to the prestressed correction construction simulation analysis for tension structures.
Xu, Zhongfeng
2012-09-01
An improved dynamical downscaling method (IDD) with general circulation model (GCM) bias corrections is developed and assessed over North America. A set of regional climate simulations is performed with the Weather Research and Forecasting Model (WRF) version 3.3 embedded in the National Center for Atmospheric Research\\'s (NCAR\\'s) Community Atmosphere Model (CAM). The GCM climatological means and the amplitudes of interannual variations are adjusted based on the National Centers for Environmental Prediction (NCEP)-NCAR global reanalysis products (NNRP) before using them to drive WRF. In this study, the WRF downscaling experiments are identical except the initial and lateral boundary conditions derived from the NNRP, original GCM output, and bias-corrected GCM output, respectively. The analysis finds that the IDD greatly improves the downscaled climate in both climatological means and extreme events relative to the traditional dynamical downscaling approach (TDD). The errors of downscaled climatological mean air temperature, geopotential height, wind vector, moisture, and precipitation are greatly reduced when the GCM bias corrections are applied. In the meantime, IDD also improves the downscaled extreme events characterized by the reduced errors in 2-yr return levels of surface air temperature and precipitation. In comparison with TDD, IDD is also able to produce a more realistic probability distribution in summer daily maximum temperature over the central U.S.-Canada region as well as in summer and winter daily precipitation over the middle and eastern United States. © 2012 American Meteorological Society.
DUAL RECIPROCITY HYBRID BOUNDARY NODE METHOD FOR THREE-DIMENSIONAL ELASTICITY WITH BODY FORCE
Institute of Scientific and Technical Information of China (English)
Fei Yan; Yuanhan Wang; Yu Miao; Fei Tan
2008-01-01
Combining Dual Reciprocity Method (DRM) with Hybrid Bòundary Node Method(HBNM),the Dual Reciprocity Hybrid Boundary Node Method (DRHBNM) is developed for three-dimensional linear elasticity problems with body force.This method can be used to solve the elasticity problems with body force without domain integral,which is inevitable by HBNM.To demonstrate the versatility and the fast convergence of this method,some numerical examples of 3-D elasticity problems with body forces are examined.The computational results show that the present method is effective and can be widely applied in solving practical engineering problems.
Institute of Scientific and Technical Information of China (English)
无
2011-01-01
[Objective] The aim was to study the driving forces of rocky desertification in Guizhou Province. [Method] Based on GIS and RS technology, the main driving forces of rocky desertification in Guizhou Province were analyzed by means of correlation analysis and variation coefficient method, and then the distribution of rocky desertification in Guizhou Province was assessed synthetically. [Result] The main driving forces of rocky desertification in Guizhou Province were vegetation cover, rainfall, peasant incom...
Villeneuve-Faure, C.; Boudou, L.; Makasheva, K.; Teyssedre, G.
2014-11-01
Charges injection and accumulation in the dielectric remains a critical issue, mainly because these phenomena are involved in a great number of failure mechanisms in cables or electronic components. Achieving a better understanding of the mechanisms leading to charge injection, transport and trapping under electrical stress and of the relevant interface phenomena is a high priority. The classical methods used for space charge density profile measurements have a limited spatial resolution, which prevents them being used for investigating thin dielectric layers or interface processes. Thus, techniques derived from atomic force microscopy (AFM) have been investigated more and more for this kind of application, but so far they have been limited by their lack of in-depth sensitivity. In this paper a new method for space charge probing is described, the electrostatic force distance curve (EFDC), which is based on electrostatic force measurements using AFM. A comparison with the results obtained using kelvin force microscopy (KFM) allowed us to highlight the fact that EFDC is sensitive to charges localized in the third-dimension.
Arnet, Ursina; van Drongelen, Stefan; Veeger, DirkJan H. E. J.; van der Woude, Lucas H. V.
2012-01-01
Objective: To investigate the influence of exercise conditions (speed and method to impose power) on the applied force, force effectiveness and distribution of work during handcycling. Method: Ten able-bodied men performed handcycling on a treadmill. To test the effect of speed, subjects propelled a
Amano, Ken-ich
2013-01-01
We propose iterative methods for obtaining solvation structures on a solid plate which use force distributions measured by surface force apparatus (SFA) and atomic force microscopy (AFM) as input data. Two model systems are considered here. In the model system for SFA, the same two solid plates are immersed in a solvent, and a probe tip and a solid plate are immersed in a solvent in the model system for AFM. Advantages of the iterative methods are as follows: The iterative method for SFA can obtain the solvation structure, for example, in a Lennard-Jones liquid; The iterative method for AFM can obtain the solvation structure without an input datum of solvation structure around the probe tip.
Lohrmann, Maike; Kappl, Michael; Butt, Hans-Juergen; Urbanetz, Nora Anne; Lippold, Bernhard Christian
2007-09-01
Dry powder inhalers mostly contain carrier based formulations where micronized drug particles are adhered to coarse carrier particles. The performance of the dry powder inhaler depends on the inhaler device, the inhalation manoeuvre and the formulation. The most important factor influencing the behaviour of the formulation is the adhesion force acting between the active ingredient and the carrier particles, which can be measured using different methods, for example the centrifuge technique or atomic force microscopy. In this study the tensile strength method, usually applied to determine cohesion forces between powder particles of one material, is optimized for adhesion force measurements between powder particles of unlike materials. Adhesion force measurements between the carrier materials lactose or mannitol and the drug substance salbutamol sulphate using the tensile strength method and the atomic force microscopy show higher values with increasing relative humidity. Consequently, the fine particle fraction determined using the Next Generation Impactor decreases with increasing relative humidity as a result of the enhanced interparticle interactions.
Silicon force sensor and method of using the same
Galambos, Paul C.; Crenshaw, Thomas B.; Nishida, Erik E.; Burnett, Damon J.; Lantz, Jeffrey W.
2016-10-04
The various technologies presented herein relate to a sensor for measurement of high forces and/or high load shock rate(s), whereby the sensor utilizes silicon as the sensing element. A plate of Si can have a thinned region formed therein on which can be formed a number of traces operating as a Wheatstone bridge. The brittle Si can be incorporated into a layered structure comprising ductile and/or compliant materials. The sensor can have a washer-like configuration which can be incorporated into a nut and bolt configuration, whereby tightening of the nut and bolt can facilitate application of a compressive preload upon the sensor. Upon application of an impact load on the bolt, the compressive load on the sensor can be reduced (e.g., moves towards zero-load), however the magnitude of the preload can be such that the load on the sensor does not translate to tensile stress being applied to the sensor.
An assessment of methods for computing radiative forcing in climate models
International Nuclear Information System (INIS)
Because the radiative forcing is rarely computed separately when performing climate model simulations, several alternative methods have been developed to estimate both the instantaneous (or direct) forcing and the adjusted forcing. The adjusted forcing accounts for the radiative impact arising from the adjustment of climate variables to the instantaneous forcing, independent of any surface warming. Using climate model experiments performed for CMIP5, we find the adjusted forcing for 4 × CO2 ranges from roughly 5.5–9 W m−2 in current models. This range is shown to be consistent between different methods of estimating the adjusted forcing. Decomposition using radiative kernels and offline double-call radiative transfer calculations indicates that the spread receives a substantial contribution (roughly 50%) from intermodel differences in the instantaneous component of the radiative forcing. Moreover, nearly all of the spread in adjusted forcing can be accounted for by differences in the instantaneous forcing and stratospheric adjustment, implying that tropospheric adjustments to CO2 play only a secondary role. This suggests that differences in modeling radiative transfer are responsible for substantial differences in the projected climate response and underscores the need to archive double-call radiative transfer calculations of the instantaneous forcing as a routine diagnostic. (letter)
A Novel Analytical Solution Method for Constraint Forces of the Kinematic Pair and Its Applications
Directory of Open Access Journals (Sweden)
Changjian Zhi
2015-01-01
Full Text Available Constraint forces of the kinematic pair are the basis of the kinematics and dynamics analysis of mechanisms. Exploring the solution method for constraint forces is a hot issue in the mechanism theory fields. Based on the observation method and the theory of reciprocal screw system, the solution method of reciprocal screw system is improved and its solution procedures become easier. This method is also applied to the solution procedure of the constraint force. The specific expressions of the constraint force are represented by the reciprocal screw system of twist. The transformation formula of twist under different coordinates is given and it make the expression of the twist of kinematic pair more facility. A slider-crank mechanism and a single loop spatial RUSR mechanism are taken as examples. It confirms that this method can be used to solve the constraint force of the planar and spatial mechanism.
An improved method for calculating force distributions in moment-stiff timber connections
DEFF Research Database (Denmark)
Ormarsson, Sigurdur; Blond, Mette
2012-01-01
An improved method for calculating force distributions in moment-stiff metal dowel-type timber connections is presented, a method based on use of three-dimensional finite element simulations of timber connections subjected to moment action. The study that was carried out aimed at determining how...... the slip modulus varies with the angle between the direction of the dowel forces and the fibres in question, as well as how the orthotropic stiffness behaviour of the wood material affects the direction and the size of the forces. It was assumed that the force distribution generated by the moment action...
An improved method for calculating force distributions in moment-stiff timber connections
DEFF Research Database (Denmark)
Ormarsson, Sigurdur; Blond, Mette
2012-01-01
An improved method for calculating force distributions in moment-stiff multi-dowel timber connections is presented, a method based on use of three-dimensional finite element simulations of timber connections subjected to moment action. The study that was carried out aimed at determining how...... the slip modulus varies with the angle between the direction of the dowel forces and the fibres in question, as well as how the orthotropic stiffness behaviour of the wood material affects the direction and the size of the forces. It was assumed that the force distribution generated by the moment action...
Stochastic number projection method in the pairing-force problem
Capote, R; Capote, Roberto; Gonzalez, Augusto
1999-01-01
A new stochastic number projection method is proposed. The component of the BCS wave function corresponding to the right number of particles is obtained by means of a Metropolis algorithm in which the weight functions are constructed from the single-particle occupation probability. Either standard BCS or Lipkin-Nogami probability distributions can be used, thus the method is applicable for any pairing strength. The accuracy of the method is tested in the computation of pairing energies of model and real systems.
Selection biases in empirical p(z) methods for weak lensing
Gruen, Daniel
2016-01-01
To measure the mass of foreground objects with weak gravitational lensing, one needs to estimate the redshift distribution of lensed background sources. This is commonly done in an empirical fashion, i.e. with a reference sample of galaxies of known spectroscopic redshift, matched to the source population. In this work, we develop a simple decision tree framework that, under the ideal conditions of a large, purely magnitude-limited reference sample, allows an unbiased recovery of the source redshift probability density function p(z), as a function of magnitude and color. We use this framework to quantify biases in empirically estimated p(z) caused by selection effects present in realistic reference and weak lensing source catalogs, namely (1) complex selection of reference objects by the targeting strategy and success rate of existing spectroscopic surveys and (2) selection of background sources by the success of object detection and shape measurement at low signal-to-noise. For intermediate-to-high redshift ...
An inverse method was developed to integrate satellite observations of atmospheric pollutant column concentrations and direct sensitivities predicted by a regional air quality model in order to discern biases in the emissions of the pollutant precursors.
Prying Force Calculation and Design Method for T-shaped Tensile Connector with High Strength Bolt
Institute of Scientific and Technical Information of China (English)
Zhaoxin Hou; Guohong Huang; Chao Gong
2015-01-01
In order to establish the design method for T⁃shaped tensile connector with high strength bolt, the theoretical analysis is carried out. Firstly, it analyzes the performance of the connector and establishes prying force calculation model. Based on the model, prying force equation and function between bolt prying force and flange thickness is derived, and the min and max thickness requirement of flange plate under a certain tension load is then obtained. Finally, two simplified design methods of the connector are proposed, which are bolt pulling capacity method and flange plate bending capacity method.
Climate model bias correction and the role of timescales
Directory of Open Access Journals (Sweden)
J. O. Haerter
2010-10-01
Full Text Available It is well known that output from climate models cannot be used to force hydrological simulations without some form of preprocessing to remove the existing biases. In principle, statistical bias correction methodologies act on model output so the statistical properties of the corrected data match those of the observations. However the improvements to the statistical properties of the data are limited to the specific time scale of the fluctuations that are considered. For example, a statistical bias correction methodology for mean daily values might be detrimental to monthly statistics. Also, in applying bias corrections derived from present day to scenario simulations, an assumption is made of persistence of the bias over the largest timescales. We examine the effects of mixing fluctuations on different time scales and suggest an improved statistical methodology, referred to here as a cascade bias correction method, that eliminates, or greatly reduces, the negative effects.
Directory of Open Access Journals (Sweden)
Vickers Andrew J
2008-11-01
Full Text Available Abstract Background A common feature of diagnostic research is that results for a diagnostic gold standard are available primarily for patients who are positive for the test under investigation. Data from such studies are subject to what has been termed "verification bias". We evaluated statistical methods for verification bias correction when there are few false negatives. Methods A simulation study was conducted of a screening study subject to verification bias. We compared estimates of the area-under-the-curve (AUC corrected for verification bias varying both the rate and mechanism of verification. Results In a single simulated data set, varying false negatives from 0 to 4 led to verification bias corrected AUCs ranging from 0.550 to 0.852. Excess variation associated with low numbers of false negatives was confirmed in simulation studies and by analyses of published studies that incorporated verification bias correction. The 2.5th – 97.5th centile range constituted as much as 60% of the possible range of AUCs for some simulations. Conclusion Screening programs are designed such that there are few false negatives. Standard statistical methods for verification bias correction are inadequate in this circumstance.
Directory of Open Access Journals (Sweden)
W. Zhu
2015-02-01
Full Text Available Dynamic flux chambers (DFCs and micrometeorological (MM methods are extensively deployed for gauging air–surface Hg0 gas exchange. However, a systematic evaluation of the precision of the contemporary Hg0 flux quantification methods is not available. In this study, the uncertainty in Hg0 flux measured by relaxed eddy accumulation (REA method, aerodynamic gradient method (AGM, modified Bowen-ratio (MBR method, as well as DFC of traditional (TDFC and novel (NDFC designs is assessed using a robust data-set from two field intercomparison campaigns. The absolute precision in Hg0 concentration difference (Δ C measurements is estimated at 0.064 ng m−3 for the gradient-based MBR and AGM system. For the REA system, the parameter is Hg0 concentration (C dependent at 0.069+0.022C. 57 and 62% of the individual vertical gradient measurements were found to be significantly different from zero during the campaigns, while for the REA-technique the percentage of significant observations was lower. For the chambers, non-significant fluxes are confined to a few nighttime periods with varying ambient Hg0 concentration. Relative bias for DFC-derived fluxes is estimated to be ~ ±10%, and ~ 85% of the flux bias are within ±2 ng m−2 h−1 in absolute term. The DFC flux bias follows a diurnal cycle, which is largely dictated by temperature controls on the enclosed volume. Due to contrasting prevailing micrometeorological conditions, the relative uncertainty (median in turbulent exchange parameters differs by nearly a factor of two between the campaigns, while that in Δ C measurements is fairly stable. The estimated flux uncertainties for the triad of MM-techniques are 16–27, 12–23 and 19–31% (interquartile range for the AGM, MBR and REA method, respectively. This study indicates that flux-gradient based techniques (MBR and AGM are preferable to REA in quantifying Hg0 flux over ecosystems with low vegetation height. A limitation of all Hg0 flux
Precise force measurement method by a Y-shaped cavity dual-frequency laser
Institute of Scientific and Technical Information of China (English)
Guangzong Xiao; Xingwu Long; Bin Zhang; Geng Li
2011-01-01
A novel precise force measurement based on a Y-shaped cavity dual-frequency laser is proposed. The principle of force measurement with this method is analyzed, and the analytic relation expression between the input force and the change in the output beat frequency is derived. Experiments using a 632.8-nm Y-shaped cavity He-Ne dual-frequency laser are then performed; they demonstrate that the force measurement is proportional to a high degree over almost five decades of input signal range. The maximum scale factor is observed as 5.02×109 Hz/N, with beat frequency instability equivalent resolution of 10-5 N. By optimizing the optical and geometrical parameters of the laser sensor, a force measurement resolution of 10-6i N could be expected.%A novel precise force measurement based on a Y-shaped cavity dual-frequency laser is proposed.The principle of force measurement with this method is analyzed,and the analytic relation expression between the input force and the change in the output beat frequency is derived.Experiments using a 632.8-nm Y-shaped cavity He-Ne dual-frequency laser are then performed;they demonstrate that the force measurement is proportional to a high degree over almost five decades of input signal range.The maximum scale factor is observed as 5.02× 109 Hz/N,with beat frequency instability equivalent resolution of 10-5 N.By optimizing the optical and geometrical parameters of the laser sensor,a force measurement resolution of 10 -6 N could be expected.Precise measurement of force and force-related nagnitudes,such as acceleration,pressure,and mass,is an often demanded task in modern engineering and science[1-3].In recent decades,some research efforts have been intensified to utilize optical measnrement procedures for obtaining precise force measurement.
Analysis of limit forces on the vehicle wheels using an algorithm of Dynamic Square Method
Brukalski, M.
2016-09-01
This article presents a method named as Dynamic Square Method (DSM) used for dynamic analysis of a vehicle equipped with a four wheel drive system. This method allows determination of maximum (limit) forces acting on the wheels. Here, the maximum longitudinal forces acting on the wheels are assumed and then used to predict whether they can be achieved by a specific dynamic motion or whether the actual friction forces under a given wheel is large enough to transfer lateral forces. For the analysis of DSM a four wheel vehicle model is used. On the basis of this characteristic it is possible to determine the maximum longitudinal force acting on the wheels of the given axle depending on the lateral acceleration of the vehicle. The results of this analysis may be useful in the development of a control algorithm used for example in active differentials.
Exploration of Local Force Calculations Using the Methods of Regularized Stokeslets
Thompson, Terese
2015-01-01
We analyze the performance of the Method of Regularized Stokeslets (MRS) and the Method of Auxiliary Regularized Stokeslets (MARS) in computing the forces necessary to translate a sphere with unit velocity in Stokes ﬂow. In particular, we explore the dependence of local and global force calculations on various parameters associated with each method. The parameters we varied include the regularization parameter, the discretization of the sphere, and the spread and placement of the auxiliary St...
A COMBINED DATA PROCESSING METHOD ON WATER IMPACT FORCE MEASUREMENT
Institute of Scientific and Technical Information of China (English)
ZHAO Meng-hua; CHEN Xiao-peng
2012-01-01
A combined method is proposed to determine the water entry acceleration at a low impact velocity through image processing.The procedure includes:(1) a sequence of images for water impact are recorded by a high speed camera,(2) the sub-pixel image processing method is employed to calculate the displacement with an accuracy on the “sub-pixel” level,(3) the acceleration of the object is acquired by differentiating the displacement twice and with results being further filtered by a carefully designed low-pass Butterworth filter.A theoretically based analysis is conducted for designing the parameters of the low-pass filters.It is shown that the water entry can be regarded as a procedure with a slowly changing velocity.The method is validated with the standard sinusoidal motion and the water entry of a sphere.This approach could be considered as an auxiliary method during the early-stage study of the water entry,and it could be further applied to some complicated circumstances,like the water entry of spinning spheres.
Improved accuracy for finite element structural analysis via an integrated force method
Patnaik, S. N.; Hopkins, D. A.; Aiello, R. A.; Berke, L.
1992-01-01
A comparative study was carried out to determine the accuracy of finite element analyses based on the stiffness method, a mixed method, and the new integrated force and dual integrated force methods. The numerical results were obtained with the following software: MSC/NASTRAN and ASKA for the stiffness method; an MHOST implementation method for the mixed method; and GIFT for the integrated force methods. The results indicate that on an overall basis, the stiffness and mixed methods present some limitations. The stiffness method generally requires a large number of elements in the model to achieve acceptable accuracy. The MHOST method tends to achieve a higher degree of accuracy for course models than does the stiffness method implemented by MSC/NASTRAN and ASKA. The two integrated force methods, which bestow simultaneous emphasis on stress equilibrium and strain compatibility, yield accurate solutions with fewer elements in a model. The full potential of these new integrated force methods remains largely unexploited, and they hold the promise of spawning new finite element structural analysis tools.
Base force element method of complementary energy principle for large rotation problems
Institute of Scientific and Technical Information of China (English)
Yijiang Peng; Yinghua Liu
2009-01-01
Using the concept of the base forces, a new finite element method (base force element method, BFEM) based on the complementary energy principle is presented for accurate modeling of structures with large displacements and large rotations. First, the complementary energy of an element is described by taking the base forces as state variables, and is then separated into deformation and rotation parts for the case of large deformation. Second, the control equations of the BFEM based on the complementary energy principle are derived using the Lagrange multiplier method. Nonlinear procedure of the BFEM is then developed. Finally, several examples are analyzed to illustrate the reliability and accuracy of the BFEM.
Pfeiffer, Helge
2015-01-01
Although, many biological systems fulfil their functions under the condition of excess hydration, the behaviour of bound water as well as the processes accompanying dehydration are nevertheless important to investigate. Dehydration can be a result of applied mechanical pressure, lowered humidity or cryogenic conditions. The effort required to dehydrate a lipid membrane at relatively low degree of hydration can be described by a disjoining pressure which is called hydration pressure or hydration force. This force is short-ranging (a few nm) and is usually considered to be independent of other surface forces, such as ionic or undulation forces. Different theories were developed to explain hydration forces that are usually not consistent with each other and which are also partially in conflict with experimental or numerical data.Over the last decades it has been more and more realised that one experimental method alone is not capable of providing much new insight into the world of such hydration forces. Therefore, research requires the comparison of results obtained from the different methods. This chapter thus deals with an overview on the theory of hydration forces, ranging from polarisation theory to protrusion forces, and presents a selection of experimental techniques appropriate for their characterisation, such as X-ray diffraction, atomic force microscopy and even calorimetry. PMID:26438262
Pfeiffer, Helge
2015-01-01
Although, many biological systems fulfil their functions under the condition of excess hydration, the behaviour of bound water as well as the processes accompanying dehydration are nevertheless important to investigate. Dehydration can be a result of applied mechanical pressure, lowered humidity or cryogenic conditions. The effort required to dehydrate a lipid membrane at relatively low degree of hydration can be described by a disjoining pressure which is called hydration pressure or hydration force. This force is short-ranging (a few nm) and is usually considered to be independent of other surface forces, such as ionic or undulation forces. Different theories were developed to explain hydration forces that are usually not consistent with each other and which are also partially in conflict with experimental or numerical data.Over the last decades it has been more and more realised that one experimental method alone is not capable of providing much new insight into the world of such hydration forces. Therefore, research requires the comparison of results obtained from the different methods. This chapter thus deals with an overview on the theory of hydration forces, ranging from polarisation theory to protrusion forces, and presents a selection of experimental techniques appropriate for their characterisation, such as X-ray diffraction, atomic force microscopy and even calorimetry.
Directory of Open Access Journals (Sweden)
MIHAELA BRATU (SIMIONESCU
2012-12-01
Full Text Available In this study some alternative forecasts for the unemployment rate of USA made by four institutions (International Monetary Fund (IMF, Organization for Economic Co-operation and Development (OECD, Congressional Budget Office (CBO and Blue Chips (BC are evaluated regarding the accuracy and the biasness. The most accurate predictions on the forecasting horizon 201-2011 were provided by IMF, followed by OECD, CBO and BC.. These results were gotten using U1 Theil’s statistic and a new method that has not been used before in literature in this context. The multi-criteria ranking was applied to make a hierarchy of the institutions regarding the accuracy and five important accuracy measures were taken into account at the same time: mean errors, mean squared error, root mean squared error, U1 and U2 statistics of Theil. The IMF, OECD and CBO predictions are unbiased. The combined forecasts of institutions’ predictions are a suitable strategy to improve the forecasts accuracy of IMF and OECD forecasts when all combination schemes are used, but INV one is the best. The filtered and smoothed original predictions based on Hodrick-Prescott filter, respectively Holt-Winters technique are a good strategy of improving only the BC expectations. The proposed strategies to improve the accuracy do not solve the problem of biasness. The assessment and improvement of forecasts accuracy have an important contribution in growing the quality of decisional process.
Iteratively reweighted generalized rank annihilation method 1. Improved handling of prediction bias
Faber, N.M.; Ferre, J.; Boque, R.
2001-01-01
The generalized rank annihilation method (GRAM) is a method for curve resolution and calibration that uses two bilinear matrices simultaneously, i.e., one for the unknown and one for the calibration sample. A GRAM calculation amounts to solving an eigenvalue problem for which the eigenvalues are rel
Investigation of Tension Forces in A Stay Cable System of A Road Bridge Using Vibration Methods
Directory of Open Access Journals (Sweden)
Hawryszków Paweł
2015-01-01
Full Text Available In the article author presents method of investigation of tension forces in stay cable systems using dynamical methods. Research was carried out during stay cable system installation on WN-24 viaduct near Poznań, that is way it was possible to compare tension forces indicated directly by devices using for tensioning of cable-stayed bridges with results achieved indirectly by means of dynamical methods. Discussion of results was presented. Advantages of dynamical methods and possible fields of application was described. This method, which has been rarely used before, may occur interesting alternative in diagnostics of bridges in comparison to traditional methods.
DEFF Research Database (Denmark)
Pøhlsgaard, Jacob; Harpsøe, Kasper; Jørgensen, Flemming Steen;
2012-01-01
molecules, including polar and charged compounds. Identifying global energy minimum conformations of such compounds with force-field methods is problematic due to the exaggeration of intramolecular electrostatic interactions. We demonstrate that the global energy minimum conformations of zwitterionic...
Numerical simulation of laminar jet-forced flow using lattice Boltzmann method
Institute of Scientific and Technical Information of China (English)
Yuan LI; Ya-li DUAN; Yan GUO; Ru-xun LIU
2009-01-01
In the paper, a numerical study on symmetrical and asymmetrical laminar jet-forced flows is carried out by using a lattice Boltzmann method (LBM) with a special boundary treatment. The simulation results are in very good agreement with the available numerical prediction. It is shown that the LBM is a competitive method for the laminar jet-forced flow in terms of computational efficiency and stability.
Force distribution in granular media studied by an energy method based on statistical mechanics
Galindo-Torres, S A
2010-01-01
In the present letter a method to find a proper expression for the force distribution inside a granular sample in static equilibrium is proposed. The method is based in statistical mechanics and the force distribution is obtained by studying how the potential elastic energy is divided among the different contacts between grains. It is found with DEM simulations with spheres that the elastic potential energy distribution follows a Bose Einstein law from which the force distribution is deduced. The present letter open a way in which granular materials can be studied with the tools provided by statistical mechanics.
2016-01-01
This book aims to cover different aspects of Bias Temperature Instability (BTI). BTI remains as an important reliability concern for CMOS transistors and circuits. Development of BTI resilient technology relies on utilizing artefact-free stress and measurement methods and suitable physics-based models for accurate determination of degradation at end-of-life, and understanding the gate insulator process impact on BTI. This book discusses different ultra-fast characterization techniques for recovery artefact free BTI measurements. It also covers different direct measurements techniques to access pre-existing and newly generated gate insulator traps responsible for BTI. The book provides a consistent physical framework for NBTI and PBTI respectively for p- and n- channel MOSFETs, consisting of trap generation and trapping. A physics-based compact model is presented to estimate measured BTI degradation in planar Si MOSFETs having differently processed SiON and HKMG gate insulators, in planar SiGe MOSFETs and also...
An Elephant in the Room: Bias in Evaluating a Required Quantitative Methods Course
Fletcher, Joseph F.; Painter-Main, Michael A.
2014-01-01
Undergraduate Political Science programs often require students to take a quantitative research methods course. Such courses are typically among the most poorly rated. This can be due, in part, to the way in which courses are evaluated. Students are generally asked to provide an overall rating, which, in turn, is widely used by students, faculty,…
Prediction of metallic nano-optical trapping forces by finite element-boundary integral method.
Pan, Xiao-Min; Xu, Kai-Jiang; Yang, Ming-Lin; Sheng, Xin-Qing
2015-03-01
The hybrid of finite element and boundary integral (FE-BI) method is employed to predict nano-optical trapping forces of arbitrarily shaped metallic nanostructures. A preconditioning strategy is proposed to improve the convergence of the iterative solution. Skeletonization is employed to speed up the design and optimization where iteration has to be repeated for each beam configuration. The radiation pressure force (RPF) is computed by vector flux of the Maxwell's stress tensor. Numerical simulations are performed to validate the developed method in analyzing the plasmonic effects as well as the optical trapping forces. It is shown that the proposed method is capable of predicting the trapping forces of complex metallic nanostructures accurately and efficiently.
Identifying social learning in animal populations: a new 'option-bias' method.
Directory of Open Access Journals (Sweden)
Rachel L Kendal
Full Text Available BACKGROUND: Studies of natural animal populations reveal widespread evidence for the diffusion of novel behaviour patterns, and for intra- and inter-population variation in behaviour. However, claims that these are manifestations of animal 'culture' remain controversial because alternative explanations to social learning remain difficult to refute. This inability to identify social learning in social settings has also contributed to the failure to test evolutionary hypotheses concerning the social learning strategies that animals deploy. METHODOLOGY/PRINCIPAL FINDINGS: We present a solution to this problem, in the form of a new means of identifying social learning in animal populations. The method is based on the well-established premise of social learning research, that--when ecological and genetic differences are accounted for--social learning will generate greater homogeneity in behaviour between animals than expected in its absence. Our procedure compares the observed level of homogeneity to a sampling distribution generated utilizing randomization and other procedures, allowing claims of social learning to be evaluated according to consensual standards. We illustrate the method on data from groups of monkeys provided with novel two-option extractive foraging tasks, demonstrating that social learning can indeed be distinguished from unlearned processes and a social learning, and revealing that the monkeys only employed social learning for the more difficult tasks. The method is further validated against published datasets and through simulation, and exhibits higher statistical power than conventional inferential statistics. CONCLUSIONS/SIGNIFICANCE: The method is potentially a significant technological development, which could prove of considerable value in assessing the validity of claims for culturally transmitted behaviour in animal groups. It will also be of value in enabling investigation of the social learning strategies deployed in
An Energy Conservative Ray-Tracing Method With a Time Interpolation of the Force Field
Energy Technology Data Exchange (ETDEWEB)
Yao, Jin [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
2015-02-10
A new algorithm that constructs a continuous force field interpolated in time is proposed for resolving existing difficulties in numerical methods for ray-tracing. This new method has improved accuracy, but with the same degree of algebraic complexity compared to Kaisers method.
Methods for imaging DNA in liquid with lateral molecular-force microscopy
Harniman, R. L.; Vicary, J. A.; Hörber, J. K. H.; Picco, L. M.; Miles, M. J.; Antognozzi, M.
2012-03-01
Shear force microscopy is not normally associated with the imaging of biomolecules in a liquid environment. Here we show that the recently developed scattered evanescent wave (SEW) detection system, combined with custom-designed vertically oriented cantilevers (VOCs), can reliably produce true non-contact images in liquid of DNA molecules. The range of cantilever spring constants for successful shear force imaging was experimentally identified between 0.05 and 0.09 N m-1. Images of λ-DNA adsorbed on mica in distilled water were obtained at scan rates of 8000 pixels s-1. A new constant-height force mapping mode for VOCs is also presented. This method is shown to control the vertical position of the tip in the sample plane with better than 1 nm accuracy. The force mode is demonstrated by mapping the shear force above λ-DNA molecules adsorbed on mica in a liquid environment at different tip-sample separations.
Institute of Scientific and Technical Information of China (English)
HUANG YunHui; SHI JunQi; WANG Lei
2008-01-01
The endowment effect is the tendency for a person to demand more in return for selling an object than he or she would be willing to pay for the same product. Thaler suggested that the reason of endowment effect lies in that selling creates a loss while buying generates a gain. Although prior research has demonstrsted the existence of loss aversion, few researchers have focused on the connection between "selling vs. buying" and "losing vs. gaining", and a recent research with a self-report method failed to find solid evidence for such a connection. The present research applied the implicit association test, a latency method, to confirm this connection. The results demonstrated that selling was more closely connected to losing while buying was more closely connected to gaining. Thus the bias resulting from loss aversion and gain preference was confirmed to be the underlying mechanism of the endowment effect. The previous failure to find such an association may be due to the insensitivity of the self-report method. Here the implication of the findings and method for experimental economic psychology is discussed.
Directory of Open Access Journals (Sweden)
BRATU (SIMIONESCU MIHAELA
2013-02-01
Full Text Available The most accurate forecasts for USA unemployment rate on the horizon 2001-2012, according to U1 Theil’s coefficient and to multi-criteria ranking methods, were provided by International Monetary Fund (IMF, being followed by other institutions as: Organization for Economic Co-operation and Development (OECD, Congressional Budget Office (CBO and Blue Chips (BC. The multi-criteria ranking methods were applied to solve the divergence in assessing the accuracy, differences observed by computing five chosen measures of accuracy: U1 and U2 statistics of Theil, mean error, mean squared error, root mean squared error. Some strategies of improving the accuracy of the predictions provided by the four institutions, which are biased in all cases, excepting BC, were proposed. However, these methods did not generate unbiased forecasts. The predictions made by IMF and OECD for 2001-2012 can be improved by constructing combined forecasts, the INV approach and the scheme proposed by author providing the most accurate expections. The BC forecasts can be improved by smoothing the predictions using Holt-Winters method and Hodrick - Prescott filter.
Energy Technology Data Exchange (ETDEWEB)
Fukushima, Edwardo F.; Hirose, Shigeo [Tokyo Inst. of Tech. (Japan)
2000-05-01
This paper introduces an attitude control scheme based in optimal force distribution using quadratic programming which minimizes joint energy consumption. This method shares similarities with force distribution for multifingered hands, multiple coordinated manipulators and legged walking robots. In particular, an attitude control scheme was introduced inside the force distribution problem, and successfully implemented for control of the articulated body mobile robot KR-II. This is an actual mobile robot composed of cylindrical segments linked in series by prismatic joints and has a long snake-like appearance. These prismatic joints are force controlled so that each segment's vertical motion can automatically follow the terrain irregularities. An attitude control is necessary because this system acts like a system of wheeled inverted pendulum carts connected in series, being unstable by nature. The validity and effectiveness of the proposed method is verified by computer simulation and experiments with the robot KR-II. (author)
A method for evaluating bias in global measurements of CO{sub 2} total columns from space
Energy Technology Data Exchange (ETDEWEB)
Wunch, D.; Wennberg, P. O.; Toon, G. C.; Connor, B. J.; Fisher, B.; Osterman, G. B.; Frankenberg, C.; Mandrake, L.; O?Dell, C.; Ahonen, P.; Biraud, S. C.; Castano, R.; Cressie, N.; Crisp, D.; Deutscher, N. M.; Eldering, A.; Fisher, M. L.; Griffith, D. W.T.; Gunson, M.; Heikkinen, P.; Keppel-Aleks, G.; Kyro, E.; Lindenmaier, R.; Macatangay, R.; Mendonca, J.; Messerschmidt, J.; Miller, C. E.; Morino, I.; Notholt, J.; Oyafuso, F. A.; Rettinger, M.; Robinson, J.; Roehl, C. M.; Salawitch, R. J.; Sherlock, V.; Strong, K.; Sussmann, R.; Tanaka, T.; Thompson, D. R.; Uchino, O.; Warneke, T.; Wofsy, S. C.
2011-08-01
We describe a method of evaluating systematic errors in measurements of total column dry-air mole fractions of CO{sub 2} (X{sub CO{sub 2}} ) from space, and we illustrate the method by applying it to the Atmospheric CO{sub 2} Observations from Space retrievals of the Greenhouse Gases Observing Satellite (ACOS-GOSAT) v2.8. The approach exploits the lack of large gradients in X{sub CO{sub 2}} south of 25{degree} S to identify large-scale offsets and other biases in the ACOS-GOSAT data with several retrieval parameters and errors in instrument calibration. We demonstrate the effectiveness of the method by comparing the ACOS-GOSAT data in the Northern Hemisphere with ground truth provided by the Total Carbon Column Observing Network (TCCON). We use the correlation between free-tropospheric temperature and X{sub CO{sub 2}} in the Northern Hemisphere to define a dynamically informed coincidence criterion between the ground-based TCCON measurements and the ACOS-GOSAT measurements. We illustrate that this approach provides larger sample sizes, hence giving a more robust comparison than one that simply uses time, latitude and longitude criteria. Our results show that the agreement with the TCCON data improves after accounting for the systematic errors. A preliminary evaluation of the improved v2.9 ACOS-GOSAT data is also discussed.
Finite Element Method Analysis of the Tooth Movement Induced by Orthodontic Forces
Meštrović, Senka; Šlaj, Mladen; Rajić, Petra
2003-01-01
The finite element method is a useful technique for measuring structural stress and for movement analyses. The objective of this investigation was to get a more accurate estimation of tooth movement depending on application point when a tipping orthodontic force is applied. The tree-dimensional model of un upper canine, consisting of 4,000 hexahedron elements with 2,367 nodes was obtained. Horizontal, orally directed 1N tipping orthodontic force was applied to the model on five...
Free and forced convective-diffusion solutions by finite element methods
Energy Technology Data Exchange (ETDEWEB)
Gartling, D.K.; Nickell, R.E.
1976-01-01
Several free and forced convective-diffusion examples are solved and compared to either laboratory experiment or closed-form analysis. The problems solved illustrate the application of finite element methods to both strongly-coupled and weakly-coupled velocity and temperature fields governed by the steady-state momentum and energy equations. Special attention is given to internal forced convection with temperature-dependent viscosity and free convection within an enclosure.
The Fast Multipole Method and Point Dipole Moment Polarizable Force Fields
Coles, Jonathan P.; Masella, Michel
2014-01-01
We present an implementation of the fast multipole method for computing coulombic electrostatic and polarization forces from polarizable force-fields based on induced point dipole moments. We demonstrate the expected $O(N)$ scaling of that approach by performing single energy point calculations on hexamer protein subunits of the mature HIV-1 capsid. We also show the long time energy conservation in molecular dynamics at the nanosecond scale by performing simulations of a protein complex embed...
A magnetostatic force inspection method for monitoring the oscillation marks of continuous casting
International Nuclear Information System (INIS)
Based on the well-known fact that ferromagnetic materials can be significantly attracted by a permanent magnet (PM), we develop an innovative magnetostatic force inspection method to monitor the oscillating marks formed during continuous casting. A small PM produces a static magnetic field that penetrates into the ferromagnetic material slab formed via continuous casting. This magnet forms a localized magnetic sensing zone (MSZ) within the ferromagnetic material. The magnetostatic force acting on the ferromagnetic material can be expressed as the Maxwell tensor integral over the surface of the ferromagnetic material within the MSZ. This force provides local surface profile information. The reaction force of the magnetostatic force acting on the PM can be measured using a laser–cantilever system (a high force resolution method), and thus the profile features of the oscillation marks can be obtained. A measuring device with a laser–cantilever system is designed, constructed, and applied in a series of prototypes and a static experiment. A numerical model is simultaneously constructed to validate the measurement results. The differences between the actual and measured profiles are analyzed. An actual steel specimen with oscillation marks is measured using this device, and the accuracy is evaluated. In summary, the potential for the application of this method in the metallurgy industry is demonstrated. (paper)
A calibration method for optical trap force by use of electrokinetic phenomena
Institute of Scientific and Technical Information of China (English)
Youli Yu; Zhenxi Zhang; Xiaolin Zhang
2006-01-01
@@ An experimental method for calibration of optical trap force upon cells by use of electrokinetic phenomena is demonstrated.An electronkinetic sample chamber system (ESCS) is designed instead of a common sample chamber and a costly automatism stage,thus the experimental setup is simpler and cheaper.Experiments indicate that the range of the trap force measured by this method is piconewton and sub-piconewton,which makes it fit for study on non-damage interaction between light and biological particles with optical tweezers especially.Since this method is relevant to particle electric charge,by applying an alternating electric field,the new method may overcome the problem of correcting drag force and allow us to measure simultaneously optical trap stiffness and particle electric charge.
Method for six-legged robot stepping on obstacles by indirect force estimation
Xu, Yilin; Gao, Feng; Pan, Yang; Chai, Xun
2016-07-01
Adaptive gaits for legged robots often requires force sensors installed on foot-tips, however impact, temperature or humidity can affect or even damage those sensors. Efforts have been made to realize indirect force estimation on the legged robots using leg structures based on planar mechanisms. Robot Octopus III is a six-legged robot using spatial parallel mechanism(UP-2UPS) legs. This paper proposed a novel method to realize indirect force estimation on walking robot based on a spatial parallel mechanism. The direct kinematics model and the inverse kinematics model are established. The force Jacobian matrix is derived based on the kinematics model. Thus, the indirect force estimation model is established. Then, the relation between the output torques of the three motors installed on one leg to the external force exerted on the foot tip is described. Furthermore, an adaptive tripod static gait is designed. The robot alters its leg trajectory to step on obstacles by using the proposed adaptive gait. Both the indirect force estimation model and the adaptive gait are implemented and optimized in a real time control system. An experiment is carried out to validate the indirect force estimation model. The adaptive gait is tested in another experiment. Experiment results show that the robot can successfully step on a 0.2 m-high obstacle. This paper proposes a novel method to overcome obstacles for the six-legged robot using spatial parallel mechanism legs and to avoid installing the electric force sensors in harsh environment of the robot's foot tips.
Method for Six-Legged Robot Stepping on Obstacles by Indirect Force Estimation
Institute of Scientific and Technical Information of China (English)
XU Yilin; GAO Feng; PAN Yang; CHAI Xun
2016-01-01
Adaptive gaits for legged robots often requires force sensors installed on foot-tips, however impact, temperature or humidity can affect or even damage those sensors. Efforts have been made to realize indirect force estimation on the legged robots using leg structures based on planar mechanisms. Robot Octopus III is a six-legged robot using spatial parallel mechanism(UP-2UPS) legs. This paper proposed a novel method to realize indirect force estimation on walking robot based on a spatial parallel mechanism. The direct kinematics model and the inverse kinematics model are established. The force Jacobian matrix is derived based on the kinematics model. Thus, the indirect force estimation model is established. Then, the relation between the output torques of the three motors installed on one leg to the external force exerted on the foot tip is described. Furthermore, an adaptive tripod static gait is designed. The robot alters its leg trajectory to step on obstacles by using the proposed adaptive gait. Both the indirect force estimation model and the adaptive gait are implemented and optimized in a real time control system. An experiment is carried out to validate the indirect force estimation model. The adaptive gait is tested in another experiment. Experiment results show that the robot can successfully step on a 0.2 m-high obstacle. This paper proposes a novel method to overcome obstacles for the six-legged robot using spatial parallel mechanism legs and to avoid installing the electric force sensors in harsh environment of the robot’s foot tips.
Method for Six-Legged Robot Stepping on Obstacles by Indirect Force Estimation
Xu, Yilin; Gao, Feng; Pan, Yang; Chai, Xun
2016-04-01
Adaptive gaits for legged robots often requires force sensors installed on foot-tips, however impact, temperature or humidity can affect or even damage those sensors. Efforts have been made to realize indirect force estimation on the legged robots using leg structures based on planar mechanisms. Robot Octopus III is a six-legged robot using spatial parallel mechanism(UP-2UPS) legs. This paper proposed a novel method to realize indirect force estimation on walking robot based on a spatial parallel mechanism. The direct kinematics model and the inverse kinematics model are established. The force Jacobian matrix is derived based on the kinematics model. Thus, the indirect force estimation model is established. Then, the relation between the output torques of the three motors installed on one leg to the external force exerted on the foot tip is described. Furthermore, an adaptive tripod static gait is designed. The robot alters its leg trajectory to step on obstacles by using the proposed adaptive gait. Both the indirect force estimation model and the adaptive gait are implemented and optimized in a real time control system. An experiment is carried out to validate the indirect force estimation model. The adaptive gait is tested in another experiment. Experiment results show that the robot can successfully step on a 0.2 m-high obstacle. This paper proposes a novel method to overcome obstacles for the six-legged robot using spatial parallel mechanism legs and to avoid installing the electric force sensors in harsh environment of the robot's foot tips.
High Precision Prediction of Rolling Force Based on Fuzzy and Nerve Method for Cold Tandem Mill
Institute of Scientific and Technical Information of China (English)
JIA Chun-yu; SHAN Xiu-ying; NIU Zhao-ping
2008-01-01
The rolling force model for cold tandem mill was put forward by using the Elman dynamic recursive network method, based on the actual measured data. Furthermore, a good assumption is put forward, which brings a full universe of discourse self-adjusting factor fuzzy control, closed-loop adjusting, based on error feedback and expertise into a rolling force prediction model, to modify prediction outputs and improve prediction precision and robustness. The simulated results indicate that the method is highly effective and the prediction precision is better than that of the traditional method. Predicted relative error is less than ±4%, so the prediction is high precise for the cold tandem mill.
A method to measure the nonlinear force caused emittance growth in a RF photoinjector
Institute of Scientific and Technical Information of China (English)
Li Zheng-Hong; Yang Zhen-Ping
2006-01-01
Based on the multi-slit method, a new method is introduced to measure the non linear force caused emittance growth in a RF photoinjector. It is possible to reconstruct the phase space of a beam under some conditions by the multi-slit method. Based on the reconstructed phase space, besides the emittance, the emittance growth from the distortion of the phase space can also be measured. The emittance growth results from the effects of nonlinear force acting on electron, which is very important for the high quality beam in a RF photoinjector.
Institute of Scientific and Technical Information of China (English)
Gaofeng Wei; Feng Tian; Gang Tang; Chengtao Wang
2012-01-01
The purpose of this study was to develop a wavelet-based method to predict muscle forces from surface electromyography (EMG) signals in vivo.The weightlifting motor task was implemented as the case study.EMG signals of biceps brachii,triceps brachii and deltoid muscles were recorded when the subject carried out a standard weightlifting motor task.The wavelet-based algorithm was used to process raw EMG signals and extract features which could be input to the Hill-type muscle force models to predict muscle forces.At the same time,the musculoskeletal model of subject's weightlifting motor task was built and simulated using the Computed Muscle Control (CMC) method via a motion capture experiment.The results of CMC were compared with the muscle force predictions by the proposed method.The correlation coefficient between two results was 0.99(p＜0.01).However,the proposed method was easier and more efficiency than the CMC method.It has potential to be used clinically to predict muscle forces in vivo.
Boundary Element Method Solution in the Time Domain For a Moving Time-Dependent Force
DEFF Research Database (Denmark)
Nielsen, Søren R.K.; Kirkegaard, Poul Henning; Rasmussen, K. M.
2001-01-01
The problem of a moving time dependent concentrated force on the surface of an elastic halfspace is of interest in the analysis of traffic generated noise. The Boundary element method (BEM) is superior to the finite element method (FEM) in solving such problems due to its inherent ability so...
Park, Hyunwook; Pan, Xiaomin; Lee, Changhoon; Choi, Jung-Il
2016-06-01
A novel immersed boundary (IB) method based on an implicit direct forcing (IDF) scheme is developed for incompressible viscous flows. The key idea for the present IDF method is to use a block LU decomposition technique in momentum equations with Taylor series expansion to construct the implicit IB forcing in a recurrence form, which imposes more accurate no-slip boundary conditions on the IB surface. To accelerate the IB forcing convergence during the iterative procedure, a pre-conditioner matrix is introduced in the recurrence formulation of the IB forcing. A Jacobi-type parameter is determined in the pre-conditioner matrix by minimizing the Frobenius norm of the matrix function representing the difference between the IB forcing solution matrix and the pre-conditioner matrix. In addition, the pre-conditioning parameter is restricted due to the numerical stability in the recurrence formulation. Consequently, the present pre-conditioned IDF (PIDF) enables accurate calculation of the IB forcing within a few iterations. We perform numerical simulations of two-dimensional flows around a circular cylinder and three-dimensional flows around a sphere for low and moderate Reynolds numbers. The result shows that PIDF yields a better imposition of no-slip boundary conditions on the IB surfaces for low Reynolds number with a fairly larger time step than IB methods with different direct forcing schemes due to the implicit treatment of the diffusion term for determining the IB forcing. Finally, we demonstrate the robustness of the present PIDF scheme by numerical simulations of flow around a circular array of cylinders, flows around a falling sphere, and two sedimenting spheres in gravity.
Hart, Ross E; Willett, Kyle W; Masters, Karen L; Cardamone, Carolin; Lintott, Chris J; Mackay, Robert J; Nichol, Robert C; Rosslowe, Christopher K; Simmons, Brooke D; Smethurst, Rebecca J
2016-01-01
The majority of galaxies in the local Universe exhibit spiral structure with a variety of forms. Many galaxies possess two prominent spiral arms, some have more, while others display a many-armed flocculent appearance. Spiral arms are associated with enhanced gas content and star-formation in the disks of low-redshift galaxies, so are important in the understanding of star-formation in the local universe. As both the visual appearance of spiral structure, and the mechanisms responsible for it vary from galaxy to galaxy, a reliable method for defining spiral samples with different visual morphologies is required. In this paper, we develop a new debiasing method to reliably correct for redshift-dependent bias in Galaxy Zoo 2, and release the new set of debiased classifications. Using these, a luminosity-limited sample of ~18,000 Sloan Digital Sky Survey spiral galaxies is defined, which are then further sub-categorised by spiral arm number. In order to explore how different spiral galaxies form, the demographic...
Hart, Ross E.; Bamford, Steven P.; Willett, Kyle W.; Masters, Karen L.; Cardamone, Carolin; Lintott, Chris J.; Mackay, Robert J.; Nichol, Robert C.; Rosslowe, Christopher K.; Simmons, Brooke D.; Smethurst, Rebecca J.
2016-10-01
The majority of galaxies in the local Universe exhibit spiral structure with a variety of forms. Many galaxies possess two prominent spiral arms, some have more, while others display a many-armed flocculent appearance. Spiral arms are associated with enhanced gas content and star formation in the discs of low-redshift galaxies, so are important in the understanding of star formation in the local universe. As both the visual appearance of spiral structure, and the mechanisms responsible for it vary from galaxy to galaxy, a reliable method for defining spiral samples with different visual morphologies is required. In this paper, we develop a new debiasing method to reliably correct for redshift-dependent bias in Galaxy Zoo 2, and release the new set of debiased classifications. Using these, a luminosity-limited sample of ˜18 000 Sloan Digital Sky Survey spiral galaxies is defined, which are then further sub-categorized by spiral arm number. In order to explore how different spiral galaxies form, the demographics of spiral galaxies with different spiral arm numbers are compared. It is found that whilst all spiral galaxies occupy similar ranges of stellar mass and environment, many-armed galaxies display much bluer colours than their two-armed counterparts. We conclude that two-armed structure is ubiquitous in star-forming discs, whereas many-armed spiral structure appears to be a short-lived phase, associated with more recent, stochastic star-formation activity.
Schulze, T L; Jordan, R A; Hung, R W
1997-11-01
Several tick sampling methods were evaluated for ixodes scapularis Say and Amblyomma americanum (I.) in oak-dominated mixed hard-wood, pitch pine-dominated, and mixed hardwood and pine forests in coastal New Jersey. Walking surveys were more efficient for collecting I. scapularis adults than dragging by a factor of > 2:1. In contrast, drag sampling yielded nearly twice as many A. americanum adults compared with walking surveys. I. scapularis subadults were rarely collected during walking surveys. A. americanum nymphs were collected from drags approximately 3:1 over walking surveys. Twice as many A. americanum larvae were obtained from drags compared with walking surveys. All developmental stages of A. americanum responded positively to carbon dioxide. Pitfall traps and leaf litter samples collected very few ticks. Tick distribution among habitats varied significantly with the sampling method chosen, and the relative ranking of sites with respect to tick abundance varied depending on the stage of tick sampled. Failure to recognize the biases in these commonly used sampling techniques can potentially lead to incorrect conclusions that can have significant adverse public health consequences. PMID:9439115
[Comparison of cell elasticity analysis methods based on atomic force microscopy indentation].
Wang, Zhe; Hao, Fengtao; Chen, Xiaohu; Yang, Zhouqi; Ding, Chong; Shang, Peng
2014-10-01
In order to investigate in greater detail the two methods based on Hertz model for analyzing force-distance curve obtained by atomic force microscopy, we acquired the force-distance curves of Hela and MCF-7 cells by atomic force microscopy (AFM) indentation in this study. After the determination of contact point, Young's modulus in different indentation depth were calculated with two analysis methods of "two point" and "slope fitting". The results showed that the Young's modulus of Hela cell was higher than that of MCF-7 cell,which is in accordance with the F-actin distribution of the two types of cell. We found that the Young's modulus of the cells was decreased with increasing indentation depth and the curve trends by "slope fitting". This indicated that the "slope fitting" method could reduce the error caused by the miscalculation of contact point. The purpose of this study was to provide a guidance for researcher to choose an appropriate method for analyzing AFM indentation force-distance curve. PMID:25764725
Directory of Open Access Journals (Sweden)
Allahyar Geramy
2015-10-01
Full Text Available Objectives: Headgears are among the effective orthodontic appliances to achieve treatment goals. Unilateral molar distal movement is sometimes needed during an orthodontic treat- ment, which can be achieved by an asymmetric headgear. Different unilateral headgears have been introduced. The main goal of this study was to analyze the force system of uni- lateral expanded outer bow asymmetric headgears by the finite element method (FEM.Materials and Methods: Six 3D finite element models of a mesiodistal slice of the maxilla containing upper first molars, their periodontal ligaments (PDLs, cancellous bone, cortical bone, and a cervical headgear with expanded outer bow attached to maxillary first molars were designed in SolidWorks 2010 and meshed in ANSYS Workbench ver. 12.1. The mod- els were the same except for the degree of outer bow expansion. The outer bow ends were loaded with 2-Newton force. The distal driving force and the net moment were evaluated.Results: A decrease in the distalizing force in the normal side molar from 1.69 N to 1.37 N was shown by increasing the degree of unilateral expansion. At the same time, the force increased from 2.19 N to 2.49 N in the expanded side molar. A net moment increasing from 2.26 N.mm to 4.64 N.mm was also shown.Conclusion: Unilateral outer bow expansion can produce different distalizing forces in mo- lars, which increase by increasing the expansion.
Isospin-violating nucleon-nucleon forces using the method of unitary transformation
Energy Technology Data Exchange (ETDEWEB)
Evgeny Epelbaum; Ulf-G. Meissner
2005-02-01
Recently, we have derived the leading and subleading isospin-breaking three-nucleon forces using the method of unitary transformation. In the present work we extend this analysis and consider the corresponding two-nucleon forces using the same approach. Certain contributions to the isospin-violating one- and two-pion exchange potential have already been discussed by various groups within the effective field theory framework. Our findings agree with the previously obtained results. In addition, we present the expressions for the subleading charge-symmetry-breaking two-pion exchange potential which were not considered before. These corrections turn out to be numerically important. Together with the three-nucleon force results presented in our previous work, the results of the present study specify completely isospin-violating nuclear force up to the order {Lambda}{sup 5}.
A new facility to realize a nanonewton force standard based on electrostatic methods
Nesterov, V.; Mueller, M.; Frumin, L. L.; Brand, U.
2009-06-01
A new differential nanoforce facility, based on a disc-pendulum with electrostatic stiffness reduction and an electrostatic force compensation for the measurement of horizontal forces in the range below 1 µN, is presented. First measurements in air over an averaging time of 50 s show a noise level of the facility of 42 pN. The method and the results of measuring the light pressure of a red He-Ne laser with a power of 7 mW (FL = 47 pN) are presented. The force measurement uncertainty of the device is below 5%, for a force to be measured of 1 nN and a measuring duration of 50 s.
Incorporation of lubrication effects into the force-coupling method for particulate two-phase flow
International Nuclear Information System (INIS)
We investigate the performance of the force-coupling method (FCM) for particulate flow at microscales. In this work, we restrict attention to flows where we may neglect fluid inertia (Stokes flows), particle inertia and Brownian motion. The FCM performs well when distances between solid boundaries are sufficiently large, however it does not capture the local effects of viscous lubrication forces for small gap widths. To improve the results, we develop a parameterization of the lubrication forces for inclusion in the model. This is based on exact results for isolated pairs of particles and single particle-wall configurations. The correction is imposed through the addition of a lubrication barrier force on affected particles. The parameterization is tested for several cases, illustrating both the improvements possible and the limitations
Institute of Scientific and Technical Information of China (English)
Wu Tuo; Chen Hongyi; Qian Dahong
2009-01-01
Based on the Gummel-Poon model of BJT, the change of the DC bias as a function of the AC input signal in RF linear power amplifiers is theoretically derived, so that the linearity of different DC bias circuits can be interpreted and compared. According to the analysis results, a quantitative adaptive DC bias circuit is proposed,which can improve the linearity and efficiency. From the simulation and test results, we draw conclusions on how to improve the design of linear power amplifier.
Shibata, Takayuki; Ito, Yasuharu; Ozawa, Tatsuya; Nagai, Moeto; Kawashima, Takahiro
2014-02-01
The introduction of biological macromolecules such as DNA, RNA, and proteins into living cells plays a crucial role in the fundamental analysis of cellular functions and mechanisms in living systems. Therefore, we have been developing an effective platform for the in vitro manipulation and analysis of biological cells at the single-cells. In this paper, we successfully demonstrated a novel intracellular delivery method of DNA into living HeLa cells via a glass micropipette based on DC-biased AC electrokinetically driven forces. We also proposed a vibration-assisted insertion method for penetrating a cell membrane to reduce cell damage. Preliminary insertion tests on homemade SICM system and FEM simulations revealed that the application of the mechanical oscillation can reduce the deformation of cells probably due to an increase in their viscous resistance. Moreover, we also found that a change in the ion current during the insertion process allows us to detect the instant when the micropipette tip penetrates the cell membrane.
Wijesinghe, Philip; Sampson, David D.; Kennedy, Brendan F.
2016-03-01
Accurate quantification of forces, applied to, or generated by, tissue, is key to understanding many biomechanical processes, fabricating engineered tissues, and diagnosing diseases. Many techniques have been employed to measure forces; in particular, tactile imaging - developed to spatially map palpation-mimicking forces - has shown potential in improving the diagnosis of cancer on the macro-scale. However, tactile imaging often involves the use of discrete force sensors, such as capacitive or piezoelectric sensors, whose spatial resolution is often limited to 1-2 mm. Our group has previously presented a type of tactile imaging, termed optical palpation, in which the change in thickness of a compliant layer in contact with tissue is measured using optical coherence tomography, and surface forces are extracted, with a micro-scale spatial resolution, using a one-dimensional spring model. We have also recently combined optical palpation with compression optical coherence elastography (OCE) to quantify stiffness. A main limitation of this work, however, is that a one-dimensional spring model is insufficient in describing the deformation of mechanically heterogeneous tissue with uneven boundaries, generating significant inaccuracies in measured forces. Here, we present a computational, finite-element method, which we term computational optical palpation. In this technique, by knowing the non-linear mechanical properties of the layer, and from only the axial component of displacement measured by phase-sensitive OCE, we can estimate, not only the axial forces, but the three-dimensional traction forces at the layer-tissue interface. We use a non-linear, three-dimensional model of deformation, which greatly increases the ability to accurately measure force and stiffness in complex tissues.
Indirect (source-free) integration method. II. Self-force consistent radial fall
Ritter, P; Spallicci, A; Cordier, S
2015-01-01
We apply our method of indirect integration, described in Part I, at fourth order, to the radial fall affected by the self-force. The Mode-Sum regularisation is performed in the Regge-Wheeler gauge using the equivalence with the harmonic gauge for this orbit. We consider also the motion subjected to a self-consistent and iterative correction determined by the self-force through osculating stretches of geodesics. The convergence of the results confirms the validity of the integration method. This work complements and justifies the analysis and the results appeared in Int. J. Geom. Meth. Mod. Phys., 11, 1450090 (2014).
HE FIELD TEST RESULTS OF GEOMETRIC-FORCE METHOD FOR TRACK STATE ESTIMATION
Directory of Open Access Journals (Sweden)
V. S. Kossov
2013-08-01
Full Text Available Purpose. Study the possibility of using geometrically-force method to determine sections of high risk of derailment in railway stations at empty wagons movement. In the test program track diagnosing subject to longitudinal forces in the freight train effecting empty wagons is provided. Methodology. To this effect empty mineral wagon and thermal cistern were equipped with strain-gauge wheel sets, strain-gauge automatic coupler and other instruments, set in the freight train weighing 4500 t. Findings. In the course of this work it was ascertained that the geometric-force ethod gives possibility to receive additional information about the track condition from the position of empty cars stability against derailment. It is shown that some sections of high risk of derailment pieces of line does not discarded by traditional ways, based on an assessment of the geometric parameters of the way. Those track sections are identified by this method, which can not be evaluated by technical means, used currently on track measurement cars. Pieces of line with low parameters on empty cars stability against derailment are individual and they are determined not only by the sizes of deviations, but their form, a combination of different types of roughness, profile and defective elements of the permanent way. Originality. Geometric-force method should be considered as complementary to the existing technology assessment of the way on the geometrical parameters; its implementation will allow revealing the track section, dangerous for the motion of empty wagons. Practical value. For the geometrically-force method realization of assessment of the way in the railway network of JSC «Russian Railways» it is proposed on the basis of the accumulated statistics and experimental data in accordance with wagons tests with a high center of gravity to develop specialized software for wagons through gauges to assess ways bygeometrically-force method that excludes the use in
Yijiang Peng; Qing Guo; Zhaofeng Zhang; Yanyan Shan
2015-01-01
The four-mid-node plane model of base force element method (BFEM) on complementary energy principle is used to analyze the rock mechanics problems. The method to simulate the crack propagation using the BFEM is proposed. And the calculation method of safety factor for rock mass stability was presented for the BFEM on complementary energy principle. The numerical researches show that the results of the BFEM are consistent with the results of conventional quadrilateral isoparametric element and...
Institute of Scientific and Technical Information of China (English)
无
2009-01-01
The vast majority of tool condition monitoring systems use the motor current instead of the cutting force as the predictor signal. The measured motor current signal is time-dependant and instable. It is difficult to detect the cutting force token signal from such motor current signal. This paper presents a method that uses the wavelet transforms to reconstruct the cutting force token signal from the current signal based on the time frequency analysis of the cutting force signal. The result of the cutting force measurement experiment shows that the proposed reconstruct method could be used to analyze the spindle current and monitor the time-varying cutting force.
Finite Element Method Based Modeling for Prediction of Cutting Forces in Micro-end Milling
Pratap, Tej; Patra, Karali
2016-04-01
Micro-end milling is one of the widely used processes for producing micro features/components in micro-fluidic systems, biomedical applications, aerospace applications, electronics and many more fields. However in these applications, the forces generated in the micro-end milling process can cause tool vibration, process instability and even cause tool breakage if not minimized. Therefore, an accurate prediction of cutting forces in micro-end milling is essential. In this work, a finite element method based model is developed using ABAQUS/Explicit 6.12 software for prediction of cutting forces in micro-end milling with due consideration of tool edge radius effect, thermo-mechanical properties and failure parameters of the workpiece material including friction behaviour at tool-chip interface. Experiments have been performed for manufacturing of microchannels on copper plate using 500 µm diameter tungsten carbide micro-end mill and cutting forces are acquired through a dynamometer. Predicted cutting forces in feed and cross feed directions are compared with experimental results and are found to be in good agreements. Results also show that FEM based simulations can be applied to analyze size effects of specific cutting forces in micro-end milling process.
Hamad, Ibrahim Abou; Novotny, Mark A; Rikvold, Per Arne
2007-01-01
We propose a new, cyclic-voltammetry based experimental technique that can not only differentiate between discontinuous and continuous phase transitions in an adsorbate layer, but also quite accurately recover equilibrium behavior from dynamic analysis of systems with a continuous phase transition. The Electrochemical first-order reversal curve (EC-FORC) diagram for a discontinuous phase transition (nucleation and growth), such as occurs in underpotential deposition, is characterized by a negative region, while such a region does not exist for a continuous phase transition, such as occurs in the electrosorption of Br on Ag(100). Moreover, for systems with a continuous phase transition, the minima of the individual EC-FORCs trace the equilibrium curve, even at very high scan rates. Since obtaining experimental data for the EC-FORC method would require only a simple reprogramming of the potentiostat used in conventional cyclic-voltammetry experiments, we believe that this method has significant potential for ea...
Application of the Characteristic Time Expansion Method for Estimating Nonlinear Restoring Forces
Directory of Open Access Journals (Sweden)
Yung-Wei Chen
2013-01-01
Full Text Available This paper proposes a characteristic time expansion method (CTEM for estimating nonlinear restoring forces. Because noisy data and numerical instability are the main causes of numerical developing problems in an inverse field, a polynomial to identify restoring forces is usually adopted to eliminate these problems. However, results of the way doing are undesirable for a high order of polynomial. To overcome this difficulty, the characteristic length (CL is introduced into the power series, and a natural regularization technique is applied to ensure numerical stability and determine the existence of a solution. As compared to previous solutions presented in other researches, the proposed method is a desirable and accurate solver for the problem of restoring the force in the inverse vibration problems.
A New Method of Desired Gait Synthesis for Biped Walking Robot Based on Ground Reaction Force
Institute of Scientific and Technical Information of China (English)
无
2000-01-01
A new method of desired gait synthesis for biped walking robot based on the ground reaction force was proposed. The relation between the ground reaction force and joint motion is derived using the D'Almbert principle. In view of dynamic walking with high stability, the ZMP(Zero Moment Point)stability criterion must be considered in the desired gait synthesis. After that, the joint trajectories of biped walking robot are decided by substituting the ground reaction force into the aforesaid relation based on the ZMP criterion. The trajectory of desired ZMP is determined by a fuzzy logic based upon the body posture of biped walking robot. The proposed scheme is simulated and experimented on a 10 degree of freedom biped walking robot. The results indicate that the proposed method is feasible.
Finite Element Based Stress Analysis of Seat Belt Using Integrated Force Method
Directory of Open Access Journals (Sweden)
Anjali Kale
2014-06-01
Full Text Available Integrated force method (IFM has been developed for solving various continuum mechanics problems, where all the internal forces are taken as independent variables. The system equilibrium equations (EE's are mathematically concatenated with the MATLAB based compatibility conditions (CC's to form the global set of equations. This paper explains the solution strategy of prototype seat-belt component using integrated force method. Actual seat belt component is taken here to verify IFM based FE element are readily used which is named as REC_5F_8D and REC_13F_16D where 5F and 13F reflects number of internal unknowns and 8D and 16D are number of total displacements respectively. The results for “Von Mises Stress” and Maximum Displacement using IFM based formulation and compared with ANSYS.
Energy Technology Data Exchange (ETDEWEB)
Guo, Ying; Lu, Qingyou, E-mail: qxl@ustc.edu.cn [High Magnetic Field Laboratory, Chinese Academy of Sciences and University of Science and Technology of China, Hefei, Anhui 230026 (China); Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei, Anhui 230026 (China); Hou, Yubin [High Magnetic Field Laboratory, Chinese Academy of Sciences and University of Science and Technology of China, Hefei, Anhui 230026 (China)
2014-05-15
We present a completely practical TunaDrive piezo motor. It consists of a central piezo stack sandwiched by two arm piezo stacks and two leg piezo stacks, respectively, which is then sandwiched and spring-clamped by a pair of parallel polished sapphire rods. It works by alternatively fast expanding and contracting the arm/leg stacks while slowly expanding/contracting the central stack simultaneously. The key point is that sufficiently fast expanding and contracting a limb stack can make its two sliding friction forces well cancel, resulting in the total sliding friction force is <10% of the total static friction force, which can help increase output force greatly. The piezo motor's high compactness, precision, and output force make it perfect in building a high-quality harsh-condition (vibration resistant) atomic resolution scanning probe microscope.
Jirschitzka, Jens; Kimmerle, Joachim; Cress, Ulrike
2016-01-01
In four studies we tested a new methodological approach to the investigation of evaluation bias. The usage of piecewise growth curve modeling allowed for investigation into the impact of people's attitudes on their persuasiveness ratings of pro- and con-arguments, measured over the whole range of the arguments' polarity from an extreme con to an extreme pro position. Moreover, this method provided the opportunity to test specific hypotheses about the course of the evaluation bias within certain polarity ranges. We conducted two field studies with users of an existing online information portal (Studies 1a and 2a) as participants, and two Internet laboratory studies with mostly student participants (Studies 1b and 2b). In each of these studies we presented pro- and con-arguments, either for the topic of MOOCs (massive open online courses, Studies 1a and 1b) or for the topic of M-learning (mobile learning, Studies 2a and 2b). Our results indicate that using piecewise growth curve models is more appropriate than simpler approaches. An important finding of our studies was an asymmetry of the evaluation bias toward pro- or con-arguments: the evaluation bias appeared over the whole polarity range of pro-arguments and increased with more and more extreme polarity. This clear-cut result pattern appeared only on the pro-argument side. For the con-arguments, in contrast, the evaluation bias did not feature such a systematic picture.
Directory of Open Access Journals (Sweden)
Jens Jirschitzka
Full Text Available In four studies we tested a new methodological approach to the investigation of evaluation bias. The usage of piecewise growth curve modeling allowed for investigation into the impact of people's attitudes on their persuasiveness ratings of pro- and con-arguments, measured over the whole range of the arguments' polarity from an extreme con to an extreme pro position. Moreover, this method provided the opportunity to test specific hypotheses about the course of the evaluation bias within certain polarity ranges. We conducted two field studies with users of an existing online information portal (Studies 1a and 2a as participants, and two Internet laboratory studies with mostly student participants (Studies 1b and 2b. In each of these studies we presented pro- and con-arguments, either for the topic of MOOCs (massive open online courses, Studies 1a and 1b or for the topic of M-learning (mobile learning, Studies 2a and 2b. Our results indicate that using piecewise growth curve models is more appropriate than simpler approaches. An important finding of our studies was an asymmetry of the evaluation bias toward pro- or con-arguments: the evaluation bias appeared over the whole polarity range of pro-arguments and increased with more and more extreme polarity. This clear-cut result pattern appeared only on the pro-argument side. For the con-arguments, in contrast, the evaluation bias did not feature such a systematic picture.
Jirschitzka, Jens; Kimmerle, Joachim; Cress, Ulrike
2016-01-01
In four studies we tested a new methodological approach to the investigation of evaluation bias. The usage of piecewise growth curve modeling allowed for investigation into the impact of people's attitudes on their persuasiveness ratings of pro- and con-arguments, measured over the whole range of the arguments' polarity from an extreme con to an extreme pro position. Moreover, this method provided the opportunity to test specific hypotheses about the course of the evaluation bias within certain polarity ranges. We conducted two field studies with users of an existing online information portal (Studies 1a and 2a) as participants, and two Internet laboratory studies with mostly student participants (Studies 1b and 2b). In each of these studies we presented pro- and con-arguments, either for the topic of MOOCs (massive open online courses, Studies 1a and 1b) or for the topic of M-learning (mobile learning, Studies 2a and 2b). Our results indicate that using piecewise growth curve models is more appropriate than simpler approaches. An important finding of our studies was an asymmetry of the evaluation bias toward pro- or con-arguments: the evaluation bias appeared over the whole polarity range of pro-arguments and increased with more and more extreme polarity. This clear-cut result pattern appeared only on the pro-argument side. For the con-arguments, in contrast, the evaluation bias did not feature such a systematic picture. PMID:26840219
Jirschitzka, Jens; Kimmerle, Joachim; Cress, Ulrike
2016-01-01
In four studies we tested a new methodological approach to the investigation of evaluation bias. The usage of piecewise growth curve modeling allowed for investigation into the impact of people’s attitudes on their persuasiveness ratings of pro- and con-arguments, measured over the whole range of the arguments’ polarity from an extreme con to an extreme pro position. Moreover, this method provided the opportunity to test specific hypotheses about the course of the evaluation bias within certain polarity ranges. We conducted two field studies with users of an existing online information portal (Studies 1a and 2a) as participants, and two Internet laboratory studies with mostly student participants (Studies 1b and 2b). In each of these studies we presented pro- and con-arguments, either for the topic of MOOCs (massive open online courses, Studies 1a and 1b) or for the topic of M-learning (mobile learning, Studies 2a and 2b). Our results indicate that using piecewise growth curve models is more appropriate than simpler approaches. An important finding of our studies was an asymmetry of the evaluation bias toward pro- or con-arguments: the evaluation bias appeared over the whole polarity range of pro-arguments and increased with more and more extreme polarity. This clear-cut result pattern appeared only on the pro-argument side. For the con-arguments, in contrast, the evaluation bias did not feature such a systematic picture. PMID:26840219
The Australian Defence Force Mental Health Prevalence and Wellbeing Study: design and methods.
Hooff, M.V.; McFarlane, A.C.; Davies, C.E.; Searle, A.K.; Fairweather-Schmidt, A.K.; Verhagen, A.F.; Benassi, H.; Hodson, S.E.
2014-01-01
BACKGROUND: The Australian Defence Force (ADF) Mental Health Prevalence and Wellbeing Study (MHPWS) is the first study of mental disorder prevalence in an entire military population. OBJECTIVE: The MHPWS aims to establish mental disorder prevalence, refine current ADF mental health screening methods
Kaljevic, Igor; Patnaik, Surya N.; Hopkins, Dale A.
1996-01-01
The Integrated Force Method has been developed in recent years for the analysis of structural mechanics problems. This method treats all independent internal forces as unknown variables that can be calculated by simultaneously imposing equations of equilibrium and compatibility conditions. In this paper a finite element library for analyzing two-dimensional problems by the Integrated Force Method is presented. Triangular- and quadrilateral-shaped elements capable of modeling arbitrary domain configurations are presented. The element equilibrium and flexibility matrices are derived by discretizing the expressions for potential and complementary energies, respectively. The displacement and stress fields within the finite elements are independently approximated. The displacement field is interpolated as it is in the standard displacement method, and the stress field is approximated by using complete polynomials of the correct order. A procedure that uses the definitions of stress components in terms of an Airy stress function is developed to derive the stress interpolation polynomials. Such derived stress fields identically satisfy the equations of equilibrium. Moreover, the resulting element matrices are insensitive to the orientation of local coordinate systems. A method is devised to calculate the number of rigid body modes, and the present elements are shown to be free of spurious zero-energy modes. A number of example problems are solved by using the present library, and the results are compared with corresponding analytical solutions and with results from the standard displacement finite element method. The Integrated Force Method not only gives results that agree well with analytical and displacement method results but also outperforms the displacement method in stress calculations.
First priciples simulations of a bias-dependent electrochemical cell
Pedroza, Luana S; Rocha, Alexandre Reily; Fernández-Serra, Marivi
2016-01-01
Understanding the local structure of liquid water at the interfaces of metallic electrodes is a key problem in aqueous-based electrochemistry. Notably the system is under an external potential bias, which makes the task of simulating this setup difficult. To correctly compute the effect of an external bias potential applied to electrodes, we combine density functional theory and non-equilibrium Green's functions methods. Our method now allows to explicitly consider an external applied bias, in direct correspondence to the experiments. In this work, we apply this methodology to study the electronic properties and atomic forces of one water molecule at the interface of gold electrodes. We find that, as expected, the water molecule is sensitive to the sign and magnitude of the applied bias.
Inertia Force Identification of Cantilever under Moving-Mass by Inverse Method
Directory of Open Access Journals (Sweden)
Qiang Chen
2012-12-01
Full Text Available In this paper, a recursive inverse method is applied to solve the identification problem of inertia force between the cantilever and moving mass. The recursive inverse method consists of two parts: Kalman filter and recursive least-square algorithm. The basic Euler-Bernoulli beam model is introduced. Then, the differential equations and the state space model of the modal responses and the inertia force can be obtained. Finally, the recursive inverse method, which is based on the discretized state function of the system, is adapted. The identification results show that the recursive inverse method is suitable to be adapted in this problem. Some characteristics of the identification results are discussed and some further conclusions are reached.
PRESSURE FORCE CONTROL FOR FABRICATION OF PLASTIC MICROFLUIDIC CHIPS WITH HOT EMBOSSING METHOD
Institute of Scientific and Technical Information of China (English)
LIU Chong; LIAO Junfeng; WANG Xiaodong; WANG Liding
2007-01-01
A pressure force control system for hot embossing of microfluidic chips is designed with a moment motor and a ball bearing lead screw. Based on the numeric PID technique, the algorithm of pulsant integral accelerated PID control is presented and the negative effects of nonlinearity from friction, clearance and saturation are eliminated. In order to improve the quick-response characteristic, independent thread technique is adopted. The method of pressure force control based on pulsant integral accelerated PID control and independent thread technique is applied with satisfactory control performance.
The Australian Defence Force Mental Health Prevalence and Wellbeing Study: design and methods
Van Hooff, Miranda; McFarlane, Alexander C; Christopher E. Davies; Searle, Amelia K.; Fairweather-Schmidt, A Kate; Verhagen, Alan; Benassi, Helen; Stephanie E Hodson
2014-01-01
Background: The Australian Defence Force (ADF) Mental Health Prevalence and Wellbeing Study (MHPWS) is the first study of mental disorder prevalence in an entire military population.Objective: The MHPWS aims to establish mental disorder prevalence, refine current ADF mental health screening methods, and identify specific occupational factors that influence mental health. This paper describes the design, sampling strategies, and methodology used in this study.Method: At Phase 1, approximately ...
A direct micropipette-based calibration method for atomic force microscope cantilevers
Liu, Baoyu; Yu, Yan; Yao, Da-Kang; Shao, Jin-Yu
2009-01-01
In this report, we describe a direct method for calibrating atomic force microscope (AFM) cantilevers with the micropipette aspiration technique (MAT). A closely fitting polystyrene bead inside a micropipette is driven by precisely controlled hydrostatic pressures to apply known loads on the sharp tip of AFM cantilevers, thus providing a calibration at the most functionally relevant position. The new method is capable of calibrating cantilevers with spring constants ranging from 0.01 to hundr...
Institute of Scientific and Technical Information of China (English)
ZHU HuangQiu; CHENG OiuLiang
2009-01-01
A bearingless motor has two sets of intercoupling stator windings, namely torque windings and sus-pension force windings. The decoupling control of the two sets is difficult and a key technology to stable operation for a bearingless motor. In this paper, a simple, reliable and accurate analysis method is put forward using the concept of flux equivalent with virtual winding currents. By this method, the suspension operation condition PB=PM±1 for bearingless motors is testified, and under the rotation condition of the motor, it is also proved that currents in suspension force windings must have the same phase sequence and frequency as torque windings to generate a stable single direction radial force in the rotor's whole circumference. On this basis, the control strategy of realizing the suspension opera-tion of the bearingless motor is presented, and a prototype of the bearingless surface-mounted per-manent magnet synchronous motor is tested. The research results have indicated that the experimen-tal results correspond with theoretical analysis adopting this method, a stable and reliable radial sus-pension force can be generated, and the validity and feasibility of this control strategy are confirmed.
Evaluation of drag force on a nonuniform particle distribution with a meshless method
Institute of Scientific and Technical Information of China (English)
Xi Wang; Changfu You
2011-01-01
A meshless Element-Free Galerkin (EFG) method was used to directly simulate the fluidization process in two dimensions. The drag force on particles was obtained by integrating the stress and shear forces on the particle surfaces. The results show that meshless methods are capable of dealing with real particle collisions, thus are superior to most mesh-based methods in reflecting the fluidization process with frequent particle collisions and suitable void fractions. Particle distribution greatly influences the drag coefficients even for the same voidage, that is, there are large differences in the average drag coefficients between nonuniform and uniform particle distributions. Different compacting directions also have different regularities, so conventional formulas such as ‘Wen and Yu' and ‘Felice' models have some deviations in such nonuniform distributions. To evaluate the influence of the nonuniformity, the drag force in multiple particle systems was simulated by using nonuniformity coefficients, CVX and Cw, to quantitatively describe the nonuniform distribution in different directions. Drag force during fluidization can be successfully evaluated by the use of Cvx alone.
Zhang, Xueyong; Ma, Jianguo
2006-11-01
A new method for simultaneous measuring the applanation force and area and a device based on this method are presented for intraocular pressure measurement. A photoelectric probe transducer acting as applalation area detector converted the diminished quantity of light returned from applanation surface of the cone prism into one electronic signal, and a micro strain gauge acting as applation force detector converted changing load related to the resilient force of the eye into another electronic signal. A 16-bit single-chip microprocessor with E2PROM in the electronic circuit played the role of a nucleus, which stored the program instructions and the interrelated data. Laboratory experiments were carried out on a stimulated cornea clamped in a Perspex chamber connected to a hydraulic manometer to obtain intraocular pressure at different levels. Preliminary trials were carried out comparing the values obtained with those of the Goldmann tonometer. Diminished quantity of the light is directly proportional to the applanation area of the cornea and the changing load detected by strain gauge is equated to the resilient force of the eye. A new kind of tonometer can be constructed based on this principle. Experimental results on a stimulated eyeball showed the present tonometer reading has good agreement with that of the Goldmann tonometer. Further study including clinical trials and application is required to evaluate the accuracy and usefulness of this method.
A method of improving the dynamic response of 3D force/torque sensors
Osypiuk, Rafał; Piskorowski, Jacek; Kubus, Daniel
2016-02-01
In the paper attention is drawn to adverse dynamic properties of filters implemented in commercial measurement systems, force/torque sensors, which are increasingly used in industrial robotics. To remedy the problem, it has been proposed to employ a time-variant filter with appropriately modulated parameters, owing to which it is possible to suppress the amplitude of the transient response and, at the same time, to increase the pulsation of damped oscillations; this results in the improvement of dynamic properties in terms of reducing the duration of transients. This property plays a key role in force control and in the fundamental problem of the robot establishing contact with rigid environment. The parametric filters have been verified experimentally and compared with filters available for force/torque sensors manufactured by JR3. The obtained results clearly indicate the advantages of the proposed solution, which may be an interesting alternative to the classic methods of filtration.
2016-01-01
Reliably estimating wildlife abundance is fundamental to effective management. Aerial surveys are one of the only spatially robust tools for estimating large mammal populations, but statistical sampling methods are required to address detection biases that affect accuracy and precision of the estimates. Although various methods for correcting aerial survey bias are employed on large mammal species around the world, these have rarely been rigorously validated. Several populations of feral horses (Equus caballus) in the western United States have been intensively studied, resulting in identification of all unique individuals. This provided a rare opportunity to test aerial survey bias correction on populations of known abundance. We hypothesized that a hybrid method combining simultaneous double-observer and sightability bias correction techniques would accurately estimate abundance. We validated this integrated technique on populations of known size and also on a pair of surveys before and after a known number was removed. Our analysis identified several covariates across the surveys that explained and corrected biases in the estimates. All six tests on known populations produced estimates with deviations from the known value ranging from -8.5% to +13.7% and <0.7 standard errors. Precision varied widely, from 6.1% CV to 25.0% CV. In contrast, the pair of surveys conducted around a known management removal produced an estimated change in population between the surveys that was significantly larger than the known reduction. Although the deviation between was only 9.1%, the precision estimate (CV = 1.6%) may have been artificially low. It was apparent that use of a helicopter in those surveys perturbed the horses, introducing detection error and heterogeneity in a manner that could not be corrected by our statistical models. Our results validate the hybrid method, highlight its potentially broad applicability, identify some limitations, and provide insight and guidance
A fast high-order method to calculate wakefield forces in an electron beam
Qiang, Ji; Ryne, Robert D
2012-01-01
In this paper we report on a high-order fast method to numerically calculate wakefield forces in an electron beam given a wake function model. This method is based on a Newton-Cotes quadrature rule for integral approximation and an FFT method for discrete summation that results in an $O(Nlog(N))$ computational cost, where $N$ is the number of grid points. Using the Simpson quadrature rule with an accuracy of $O(h^4)$, where $h$ is the grid size, we present numerical calculation of the wakefields from a resonator wake function model and from a one-dimensional coherent synchrotron radiation (CSR) wake model. Besides the fast speed and high numerical accuracy, the calculation using the direct line density instead of the first derivative of the line density avoids numerical filtering of the electron density function for computing the CSR wakefield force.
Knowledge-Based Trajectory Error Pattern Method Applied to an Active Force Control Scheme
Directory of Open Access Journals (Sweden)
Endra Pitowarno, Musa Mailah, Hishamuddin Jamaluddin
2012-08-01
Full Text Available The active force control (AFC method is known as a robust control scheme that dramatically enhances the performance of a robot arm particularly in compensating the disturbance effects. The main task of the AFC method is to estimate the inertia matrix in the feedback loop to provide the correct (motor torque required to cancel out these disturbances. Several intelligent control schemes have already been introduced to enhance the estimation methods of acquiring the inertia matrix such as those using neural network, iterative learning and fuzzy logic. In this paper, we propose an alternative scheme called Knowledge-Based Trajectory Error Pattern Method (KBTEPM to suppress the trajectory track error of the AFC scheme. The knowledge is developed from the trajectory track error characteristic based on the previous experimental results of the crude approximation method. It produces a unique, new and desirable error pattern when a trajectory command is forced. An experimental study was performed using simulation work on the AFC scheme with KBTEPM applied to a two-planar manipulator in which a set of rule-based algorithm is derived. A number of previous AFC schemes are also reviewed as benchmark. The simulation results show that the AFC-KBTEPM scheme successfully reduces the trajectory track error significantly even in the presence of the introduced disturbances.Key Words: Active force control, estimated inertia matrix, robot arm, trajectory error pattern, knowledge-based.
Accurate computation of surface stresses and forces with immersed boundary methods
Goza, Andres; Liska, Sebastian; Morley, Benjamin; Colonius, Tim
2016-09-01
Many immersed boundary methods solve for surface stresses that impose the velocity boundary conditions on an immersed body. These surface stresses may contain spurious oscillations that make them ill-suited for representing the physical surface stresses on the body. Moreover, these inaccurate stresses often lead to unphysical oscillations in the history of integrated surface forces such as the coefficient of lift. While the errors in the surface stresses and forces do not necessarily affect the convergence of the velocity field, it is desirable, especially in fluid-structure interaction problems, to obtain smooth and convergent stress distributions on the surface. To this end, we show that the equation for the surface stresses is an integral equation of the first kind whose ill-posedness is the source of spurious oscillations in the stresses. We also demonstrate that for sufficiently smooth delta functions, the oscillations may be filtered out to obtain physically accurate surface stresses. The filtering is applied as a post-processing procedure, so that the convergence of the velocity field is unaffected. We demonstrate the efficacy of the method by computing stresses and forces that converge to the physical stresses and forces for several test problems.
A piecewise-integration method for simulating the influence of external forcing on climate
Institute of Scientific and Technical Information of China (English)
Zhifu Zhang; Chongjian Qiu; Chenghai Wang
2008-01-01
Climate drift occurs in most general circulation models (GCMs) as a result of incomplete physical and numerical representation of the complex climate system,which may cause large uncertainty in sensitivity experiments evaluating climate response to changes in external forcing.To solve this problem,we propose a piecewise-integration method to reduce the systematic error in climate sensitivity studies.The observations are firstly assimilated into a numerical model by using the dynamic relaxation technique to relax to the current state of atmosphere,and then the assimilated fields are continuously used to reinitialize the simulation to reduce the error of climate simulation.When the numerical model is integrated with changed external forcing,the results can be split into two parts,background and perturbation fields,and the background is the state before the external forcing is changed.The piecewise-integration method is used to continuously reinitialize the model with the assimilated field,instead of the background.Therefore,the simulation error of the model with the external forcing can be reduced.In this way,the accuracy of climate sensitivity experiments is greatly improved.Tests with a simple low-order spectral model show that this approach can significantly reduce the uncertainty of climate sensitivity experiments.
New method of space debris cleaning based on light negative force: tractor laser
Sun, Qiongge; Gao, Long; Li, Chen
2016-01-01
This paper presents a new way of space debris removal and protection, that is, using tractor laser, which based on light negative force, to achieve space debris cleaning and shielded. Tractor laser is traceable from the theory of optical tweezers, accompanied with non-diffraction beam. These kind of optical beams have the force named negative force pointing to optical source, this will bring the object along the trajectory of laser beam moving to the optical source. The negative force leads to the new method to convey and sampling the space micro-objects. In this paper, the application of tractor laser in the space debris collection and protection of 1cm is studied. The application of the several tractor beams in the space debris and sample collection is discussed. The proposed method can reduce the requirements of the laser to the satellite platform, and realize the collection of space debris, make the establishment of the space garbage station possible, and help to study the spatial non contact sample transmission and reduce the risk of space missions.
Threshold control based bias adjustment method for electromagnetic flowmeter%阈值控制的电磁流量计偏置调节方法
Institute of Scientific and Technical Information of China (English)
梁利平; 徐科军; 张然; 张振
2013-01-01
电磁流量传感器输出信号存在低频漂移的偏置干扰,若不处理就直接放大,会使运放饱和,导致电磁流量计无法正常工作.一种基于阈值控制的偏置调节方法.在系统初始化阶段,计算偏置调节系数K;在流量测量过程中,根据阈值判断信号是否需要调整偏置；若需要调整,则在下一个励磁周期的开始时刻更新DAC输出,一次性将信号偏置调整回零伏附近.该方法避免了频繁调节偏置,保留了信号的原始特性,便于后续处理.针对调整过程所产生的阶跃干扰,改进了数字信号处理算法,确保测量精度.仿真实验和实际水流量标定实验证明,该偏置调整方法是可行的和有效的.%There is the low frequency drift bias interference in the electromagnetic flow sensor output signal. If the signal is amplified directly without processing, the amplifier will be in saturation, and the electromagnetic flowmeter cannot work normally. Therefore, a threshold control based bias adjustment method is proposed in this paper. In the initialization stage of the system, the adjustment coefficient K is calculated. During the flow measurement process, whether the signal needed to be adjusted is determined according to the threshold. If the bias adjustment is needed, the DAC output will be updated at the beginning of the next excitation cycle to adjust the signal bias to zero voltage at one time. This method avoids frequent bias adjustment, retains signal's original characteristics, and facilitates subsequent processing. The digital signal processing algorithms are improved by removing the step interference caused by the bias adjustment, and the measurement accuracy is ensured. The simulation and the water flow calibration experiments show that the bias adjustment method is feasible and effective.
Guo, Ying; Hou, Yubin; Lu, Qingyou
2014-05-01
We present a completely practical TunaDrive piezo motor. It consists of a central piezo stack sandwiched by two arm piezo stacks and two leg piezo stacks, respectively, which is then sandwiched and spring-clamped by a pair of parallel polished sapphire rods. It works by alternatively fast expanding and contracting the arm/leg stacks while slowly expanding/contracting the central stack simultaneously. The key point is that sufficiently fast expanding and contracting a limb stack can make its two sliding friction forces well cancel, resulting in the total sliding friction force is piezo motor's high compactness, precision, and output force make it perfect in building a high-quality harsh-condition (vibration resistant) atomic resolution scanning probe microscope.
Structure prediction of an S-layer protein by the mean force method
Horejs, C.; Pum, D.; Sleytr, U. B.; Tscheliessnig, R.
2008-02-01
S-layer proteins have a wide range of application potential due to their characteristic features concerning self-assembling, assembling on various surfaces, and forming of isoporous structures with functional groups located on the surface in an identical position and orientation. Although considerable knowledge has been experimentally accumulated on the structure, biochemistry, assemble characteristics, and genetics of S-layer proteins, no structural model at atomic resolution has been available so far. Therefore, neither the overall folding of the S-layer proteins—their tertiary structure—nor the exact amino acid or domain allocations in the lattices are known. In this paper, we describe the tertiary structure prediction for the S-layer protein SbsB from Geobacillus stearothermophilus PV72/p2. This calculation was based on its amino acid sequence using the mean force method (MF method) achieved by performing molecular dynamic simulations. This method includes mainly the thermodynamic aspects of protein folding as well as steric constraints of the amino acids and is therefore independent of experimental structure analysis problems resulting from biochemical properties of the S-layer proteins. Molecular dynamic simulations were performed in vacuum using the simulation software NAMD. The obtained tertiary structure of SbsB was systematically analyzed by using the mean force method, whereas the verification of the structure is based on calculating the global free energy minimum of the whole system. This corresponds to the potential of mean force, which is the thermodynamically most favorable conformation of the protein. Finally, an S-layer lattice was modeled graphically using CINEMA4D and compared with scanning force microscopy data down to a resolution of 1nm. The results show that this approach leads to a thermodynamically favorable atomic model of the tertiary structure of the protein, which could be verified by both the MF Method and the lattice model.
Daniell method for power spectral density estimation in atomic force microscopy.
Labuda, Aleksander
2016-03-01
An alternative method for power spectral density (PSD) estimation--the Daniell method--is revisited and compared to the most prevalent method used in the field of atomic force microscopy for quantifying cantilever thermal motion--the Bartlett method. Both methods are shown to underestimate the Q factor of a simple harmonic oscillator (SHO) by a predictable, and therefore correctable, amount in the absence of spurious deterministic noise sources. However, the Bartlett method is much more prone to spectral leakage which can obscure the thermal spectrum in the presence of deterministic noise. By the significant reduction in spectral leakage, the Daniell method leads to a more accurate representation of the true PSD and enables clear identification and rejection of deterministic noise peaks. This benefit is especially valuable for the development of automated PSD fitting algorithms for robust and accurate estimation of SHO parameters from a thermal spectrum. PMID:27036781
Wagenaar, J J T; Donkersloot, R J; Marsman, F; de Wit, M; Bossoni, L; Oosterkamp, T H
2016-01-01
We present an innovative method for magnetic resonance force microscopy (MRFM) with ultra-low dissipation, by using the higher modes of the mechanical detector as radio frequency (rf) source. This method allows MRFM on samples without the need to be close to an rf source. Furthermore, since rf sources require currents that give dissipation, our method enables nuclear magnetic resonance experiments at ultra-low temperatures. Removing the need for an on-chip rf source is an important step towards a MRFM which can be widely used in condensed matter physics.
The fast multipole method and point dipole moment polarizable force fields
Coles, Jonathan P.; Masella, Michel
2015-01-01
We present an implementation of the fast multipole method for computing Coulombic electrostatic and polarization forces from polarizable force-fields based on induced point dipole moments. We demonstrate the expected O(N) scaling of that approach by performing single energy point calculations on hexamer protein subunits of the mature HIV-1 capsid. We also show the long time energy conservation in molecular dynamics at the nanosecond scale by performing simulations of a protein complex embedded in a coarse-grained solvent using a standard integrator and a multiple time step integrator. Our tests show the applicability of fast multipole method combined with state-of-the-art chemical models in molecular dynamical systems.
Directory of Open Access Journals (Sweden)
Allahyar Geramy
2015-10-01
Full Text Available Objectives: This study sought to assess distal and lateral forces and moments of asymmetric headgears by variable outer bow lengths.Materials and Methods: Four 3D finite element method (FEM models of a cer- vical headgear attached to the maxillary first molars were designed in SolidWorks2010 software and transferred to ANSYS Workbench ver. 11 software. Modelscontained the first molars, their periodontal ligament (PDL, cancellous and cor- tical bones, a mesiodistal slice of the maxillae and the headgear. Models were the same except for the outer bow length in headgears. The headgear was symmetric in model 1. In models 2 to 4, the headgears were asymmetric in length with dif- ferences of 5mm, 10mm and 15mm, respectively. A 2.5 N force in horizontal plane was applied and the loading manner of each side of the outer bow was cal- culated trigonometrically using data from a volunteer.Results: The 15mm difference in outer bow length caused the greatest difference in lateral (=0.21 N and distal (= 1.008 N forces and also generated moments (5.044 N.mm.Conclusion: As the difference in outer bow length became greater, asymmetric effects increased. Greater distal force in the longer arm side was associated with greater lateral force towards the shorter arm side and more net yawing moment. Clinical Relevance:A difference range of 1mm to 15 mm of length in cervical headgear can be consi-dered as a safe length of outer bow shortening in clinical use.
Haff, G Gregory; Ruben, Ryan P; Lider, Joshua; Twine, Corey; Cormie, Prue
2015-02-01
Twelve female division I collegiate volleyball players were recruited to examine the reliability of several methods for calculating the rate of force development (RFD) during the isometric midthigh clean pull. All subjects were familiarized with the isometric midthigh clean pull and participated in regular strength training. Two isometric midthigh clean pulls were performed with 2 minutes rest between each trail. All measures were performed in a custom isometric testing device that included a step-wise adjustable bar and a force plate for measuring ground reaction forces. The RFD during predetermined time zone bands (0-30, 0-50, 0-90, 0-100, 0-150, 0-200, and 0-250 milliseconds) was then calculated by dividing the force at the end of the band by the band's time interval. The peak RFD was then calculated with the use of 2, 5, 10, 20, 30, and 50 milliseconds sampling windows. The average RFD (avgRFD) was calculated by dividing the peak force (PF) by the time to achieve PF. All data were analyzed with the use of intraclass correlation alpha (ICCα) and the coefficient of variation (CV) and 90% confidence intervals. All predetermined RFD time bands were deemed reliable based on an ICCα >0.95 and a CV <4%. Conversely, the avgRFD failed to meet the reliability standards set for this study. Overall, the method used to assess the RFD during an isometric midthigh clean pull impacts the reliability of the measure and predetermined RFD time bands should be used to quantify the RFD. PMID:25259470
Bias in Dynamic Monte Carlo Alpha Calculations
Energy Technology Data Exchange (ETDEWEB)
Sweezy, Jeremy Ed [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Nolen, Steven Douglas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Adams, Terry R. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Trahan, Travis John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
2015-02-06
A 1/N bias in the estimate of the neutron time-constant (commonly denoted as α) has been seen in dynamic neutronic calculations performed with MCATK. In this paper we show that the bias is most likely caused by taking the logarithm of a stochastic quantity. We also investigate the known bias due to the particle population control method used in MCATK. We conclude that this bias due to the particle population control method is negligible compared to other sources of bias.
Directory of Open Access Journals (Sweden)
S. C. van Pelt
2009-12-01
Full Text Available Studies have demonstrated that precipitation on Northern Hemisphere mid-latitudes has increased in the last decades and that it is likely that this trend will continue. This will have an influence on discharge of the river Meuse. The use of bias correction methods is important when the effect of precipitation change on river discharge is studied. The objective of this paper is to investigate the effect of using two different bias correction methods on output from a Regional Climate Model (RCM simulation. In this study a Regional Atmospheric Climate Model (RACMO2 run is used, forced by ECHAM5/MPIOM under the condition of the SRES-A1B emission scenario, with a 25 km horizontal resolution. The RACMO2 runs contain a systematic precipitation bias on which two bias correction methods are applied. The first method corrects for the wet day fraction and wet day average (WD bias correction and the second method corrects for the mean and coefficient of variance (MV bias correction. The WD bias correction initially corrects well for the average, but it appears that too many successive precipitation days were removed with this correction. The second method performed less well on average bias correction, but the temporal precipitation pattern was better. Subsequently, the discharge was calculated by using RACMO2 output as forcing to the HBV-96 hydrological model. A large difference was found between the simulated discharge of the uncorrected RACMO2 run, the WD bias corrected run and the MV bias corrected run. These results show the importance of an appropriate bias correction.
Directory of Open Access Journals (Sweden)
S. C. van Pelt
2009-06-01
Full Text Available Studies have demonstrated that precipitation on Northern Hemisphere mid-latitudes has increased in the last decades and that it is likely that this trend will continue. This will have an influence on discharge of the river Meuse. The use of bias correction methods is important when the effect of precipitation change on river discharge is studied. The objective of this paper is to investigate the effect of using two different bias correction methods on output from a Regional Climate Model (RCM simulation. In this study a Regional Atmospheric Climate Model (RACMO2 run is used, forced by ECHAM-5 under the condition of the SRES-A1B emission scenario, with a 25 km horizontal resolution. The RACMO2 runs contain a systematic precipitation bias on which two bias correction methods are applied. The first method corrects for the wet day fraction and wet day average (WD bias correction and the second method corrects for the mean and coefficient of variance (MV bias correction. The WD bias correction initially corrects well for the average, but it appears that too many successive precipitation days were removed with this correction. The second method performed less well on average bias correction, but the temporal precipitation pattern was better. Subsequently, the discharge was calculated by using RACMO2 output as forcing to the HBV-96 hydrological model. A large difference was found between the simulated discharge of the uncorrected RACMO2 run, the WD bias corrected run and the MV bias corrected run. These results show the importance of an appropriate bias correction.
Application of Base Force Element Method to Mesomechanics Analysis for Recycled Aggregate Concrete
Yijiang Peng; Yinghua Liu; Jiwei Pu; Lijuan Zhang
2013-01-01
The base force element method (BFEM) on potential energy principle is used to analyze recycled aggregate concrete (RAC) on mesolevel. The model of BFEM with triangular element is derived. The recycled aggregate concrete is taken as five-phase composites consisting of natural coarse aggregate, new mortar, new interfacial transition zone (ITZ), old mortar, and old ITZ on meso-level. The random aggregate model is used to simulate the mesostructure of recycled aggregate concrete. The mechanics pr...
Casimir Forces via Worldline Numerics: Method Improvements and Potential Engineering Applications
Aehlig, Klaus; Fischbacher, Thomas; Gerhard, Jochen
2011-01-01
The string theory inspired Worldline Numerics approach to Casimir force calculations has some favourable characteristics that might make it well suited for geometric optimization problems as they arise e.g. in NEMS device engineering. We explain this aspect in detail, developing some refinements of the method along the way. Also, we comment on the problem of generalizing Worldline Numerics from scalars to photons in the presence of conductors.
Application of Base Force Element Method to Mesomechanics Analysis for Concrete
2014-01-01
The base force element method (BFEM) on damage mechanics is used to analyze the compressive strength, the size effects of compressive strength, and fracture process of concrete at mesolevel. The concrete is taken as three-phase composites consisting of coarse aggregate, hardened cement mortar, and interfacial transition zone (ITZ) on mesolevel. The random aggregate model is used to simulate the mesostructure of concrete. The mechanical properties and fracture process of concrete under uniaxia...
Amano, Ken-ichi
2012-01-01
Recent surface force apparatus (SFA) and atomic force microscopy (AFM) can measure force curves between a probe and a sample surface in solvent. The force curve is thought as the solvation structure in some articles, because its shape is generally oscilltive and pitch of the oscillation is about the same as diameter of the solvent. However, it is not the solvation structure. It is just only a mean force between the probe and the sample surface. Therefore, a relation between the mean force and the solvation structure must be elucidated theoretically to deepen understanding of the measured result (the mean force). In this letter, we briefly explain the relation and a method for comparing the measured mean force and the solvation structure (obtained by a simulation or a liquid theory) by using basic statistical mechanics of liquid.
Hansen, Clint; Venture, Gentiane; Rezzoug, Nasser; Gorce, Philippe; Isableu, Brice
2014-05-01
Over the last decades a variety of research has been conducted with the goal to improve the Body Segment Inertial Parameters (BSIP) estimations but to our knowledge a real validation has never been completely successful, because no ground truth is available. The aim of this paper is to propose a validation method for a BSIP identification method (IM) and to confirm the results by comparing them with recalculated contact forces using inverse dynamics to those obtained by a force plate. Furthermore, the results are compared with the recently proposed estimation method by Dumas et al. (2007). Additionally, the results are cross validated with a high velocity overarm throwing movement. Throughout conditions higher correlations, smaller metrics and smaller RMSE can be found for the proposed BSIP estimation (IM) which shows its advantage compared to recently proposed methods as of Dumas et al. (2007). The purpose of the paper is to validate an already proposed method and to show that this method can be of significant advantage compared to conventional methods.
Development of methods of male contraception： impact of the World Health Organization Task Force
Institute of Scientific and Technical Information of China (English)
GeoffreyM.H.WaitesSc.D
2003-01-01
Objective:To give an historical record of the research of the World Health Organization (WHO) Task Force to develop methods of male contraception; to examine the social, political, medical, pharmaceutical, funding, and other factors that influenced progress; and to suggest reasons why such methods are only now becoming available. Design:Review of basic and clinical research over 30 years. Setting: Task force of a multinational Objective:To give an historical agency and collaborating agencies. Conclusion(s): Through the involvement of many international scientists, the WHO Task Force has uniquely contributed to the exploratory phases of the research in male contraception and by its multicenter contraceptive efficacy studies has accelerated progress towards the ideal hormonal method. Despite an adverse climate involving social and political attitudes, funding constraints, and pharmaceutical industry hesitations, WHO formed coalitions with governments and international agencies to sustain research with results that apply to men in culturally diverse populations and thereby to influence activities across the whole range of global reproductive health and family planning.
Osuch, Marzena; Lawrence, Deborah; Meresa, Hadush K.; Napiórkowski, Jaroslaw J.; Romanowicz, Renata J.
2016-04-01
The aim of the study is an estimation of the uncertainty in flood indices introduced by bias correction of climate model variables in ten catchments in Poland. A simulation approach is used to obtain daily flows in catchments under changing climatic conditions, following the RCP4.5 and RCP8.5 emission scenarios. Climate projections were obtained from the EURO-CORDEX initiative, and time series of precipitation and air temperature from different RCM/GCMs for the periods: 1971-2000, 2021-2050 and 2071-2100 were used. The climate model outputs in the Poland area are highly biased; therefore, additional post processing in the form of bias correction of precipitation and temperature is needed. In this work we used four versions of the quantile mapping method (empirical quantile mapping, and three distribution based mappings: double gamma, single gamma and Birnbaum-Sanders) for correction of the precipitation time series and one method for air temperature correction (empirical quantile method). The HBV rainfall-runoff catchment-based model is used to estimate future flow time series. The models are calibrated using the available precipitation, air temperature, and flow observations for the period 1971-2000. Model performance is evaluated using observed data for the period 2001-2010. We also verify performance using the EURO-CORDEX simulations for the reference period (1971-2000), both with and without bias correction of the RCM/GCM outputs. Finally, the models are run for the future climate simulated by the RCM/GCM models for the years: 2021-2050 and 2071-2100. Changes in the mean annual flood and in flood quantiles are analysed and the effect of bias correction on the estimated changes is also considered. The results indicate substantial differences between climate models and catchments. The regional variability has a close relationship with the flood regime type. Catchments where high flows are expected to increase have a rainfall-dominated flood regime in the current
International Nuclear Information System (INIS)
We suggest uncertainty compensation methods for the quantification of nanoscale indentation using atomic force microscopy (AFM). The main error factors in the force–distance curves originated from the difference between theoretical and real shape of AFM tip during nanoscale indentation measurements. For the uncertainty compensations of tip shapes and misalignment of loading axis, we applied the enhanced tip geometry function and Y-scanner moving to the AFM measurements. Three different materials such as Si wafer, glass, and Au film were characterized with these compensation methods. By applying compensation methods, our results show the decreased values from 167% to 39% below 100 nm indenting depth compared with the literature values. These compensation methods applied to thin films will show the advanced quantitative analysis of hardness measurements using nanoscale indenting AFM. - Highlights: • We suggest uncertainty compensation methods for quantitative hardness measurement. • The main errors during indentation are tip geometry and non-uniform loading. • 3D tip characterization is obtained by using atomic force microscope scan. • The compensation methods perform well in thin films below thickness of 100 nm
The Fast Multipole Method and Point Dipole Moment Polarizable Force Fields
Coles, Jonathan P
2014-01-01
We present a momentum conserving implementation of the fast multipole method for computing coulombic electrostatic and polarization forces from polarizable force-fields based on induced point dipole moments. We demonstrate the expected $O(N)$ scaling of that approach by performing single energy point calculations on hexamer protein subunits of the mature HIV-1 capsid. We also show the long time energy conservation in molecular dynamics at the nanosecond scale by performing simulations of a protein complex embedded in a coarse-grained solvent using both a standard integrator and a multiple time step one. Our tests show the applicability of FMM combined with state-of-the-art chemical models in molecular dynamical systems.
Central-force decomposition of spline-based modified embedded atom method potential
Winczewski, S.; Dziedzic, J.; Rybicki, J.
2016-10-01
Central-force decompositions are fundamental to the calculation of stress fields in atomic systems by means of Hardy stress. We derive expressions for a central-force decomposition of the spline-based modified embedded atom method (s-MEAM) potential. The expressions are subsequently simplified to a form that can be readily used in molecular-dynamics simulations, enabling the calculation of the spatial distribution of stress in systems treated with this novel class of empirical potentials. We briefly discuss the properties of the obtained decomposition and highlight further computational techniques that can be expected to benefit from the results of this work. To demonstrate the practicability of the derived expressions, we apply them to calculate stress fields due to an edge dislocation in bcc Mo, comparing their predictions to those of linear elasticity theory.
Accurate computation of surface stresses and forces with immersed boundary methods
Goza, Andres; Morley, Benjamin; Colonius, Tim
2016-01-01
Many immersed boundary methods solve for surface stresses that impose the velocity boundary conditions on an immersed body. These surface stresses may contain spurious oscillations that make them ill-suited for representing the physical surface stresses on the body. Moreover, these inaccurate stresses often lead to unphysical oscillations in the history of integrated surface forces such as the coefficient of lift. While the errors in the surface stresses and forces do not necessarily affect the convergence of the velocity field, it is desirable, especially in fluid-structure interaction problems, to obtain smooth and convergent stress distributions on the surface. To this end, we show that the equation for the surface stresses is an integral equation of the first kind whose ill-posedness is the source of spurious oscillations in the stresses. We also demonstrate that for sufficiently smooth delta functions, the oscillations may be filtered out to obtain physically accurate surface stresses. The filtering is a...
Application of stochastic variational method to 3-4 body systems with realistic nuclear force
Energy Technology Data Exchange (ETDEWEB)
Ohbayashi, Yoshihide [Niigata Univ. (Japan); Varga, K.; Suzuki, Yoshiyuki
1997-05-01
SVM (stochastic variational method) was applied to simulate triton and alpha with realistic nuclear force such as Reid V8 (RV8), Argonne V6, V8 (AV6 and aV8). 3-4 body systems were solved by about 300-400 dimensions and the results were agreed with the most accurate solution. Convergence of energy of 3-4 body systems was rapid by using AV6 and AV8 potential, but it was slow by RV8 with strong repulsive force core. The energy values using SVM and GFMC were almost same. Number of dimension to convert the energy of triton was decreased by refinement. (S.Y.)
A simple method to construct soliton-like solution of the general KdV equation with external force
Institute of Scientific and Technical Information of China (English)
JiefangZHANG; FengminWU
2000-01-01
A simple and direct method is described to construct the soliton-like solution for the general KdV equation with external force. Crucial to the method is the assumption that the solution chosen is a special truncated expansion.
A direct micropipette-based calibration method for atomic force microscope cantilevers
Energy Technology Data Exchange (ETDEWEB)
Liu Baoyu; Yu Yan; Yao Dakang; Shao Jinyu [Department of Biomedical Engineering, Washington University, Saint Louis, Missouri 63130 (United States)
2009-06-15
In this report, we describe a direct method for calibrating atomic force microscope (AFM) cantilevers with the micropipette aspiration technique (MAT). A closely fitting polystyrene bead inside a micropipette is driven by precisely controlled hydrostatic pressures to apply known loads on the sharp tip of AFM cantilevers, thus providing a calibration at the most functionally relevant position. The new method is capable of calibrating cantilevers with spring constants ranging from 0.01 to hundreds of newtons per meter. Under appropriate loading conditions, this new method yields measurement accuracy and precision both within 10%, with higher performance for softer cantilevers. Furthermore, this method may greatly enhance the accuracy and precision of calibration for colloidal probes.
Adaptive method for real-time gait phase detection based on ground contact forces.
Yu, Lie; Zheng, Jianbin; Wang, Yang; Song, Zhengge; Zhan, Enqi
2015-01-01
A novel method is presented to detect real-time gait phases based on ground contact forces (GCFs) measured by force sensitive resistors (FSRs). The traditional threshold method (TM) sets a threshold to divide the GCFs into on-ground and off-ground statuses. However, TM is neither an adaptive nor real-time method. The threshold setting is based on body weight or the maximum and minimum GCFs in the gait cycles, resulting in different thresholds needed for different walking conditions. Additionally, the maximum and minimum GCFs are only obtainable after data processing. Therefore, this paper proposes a proportion method (PM) that calculates the sums and proportions of GCFs wherein the GCFs are obtained from FSRs. A gait analysis is then implemented by the proposed gait phase detection algorithm (GPDA). Finally, the PM reliability is determined by comparing the detection results between PM and TM. Experimental results demonstrate that the proposed PM is highly reliable in all walking conditions. In addition, PM could be utilized to analyze gait phases in real time. Finally, PM exhibits strong adaptability to different walking conditions.
Edelstein, Stuart J; Changeux, Jean-Pierre
2016-09-01
G-protein-coupled receptors (GPCRs) constitute a large group of integral membrane proteins that transduce extracellular signals from a wide range of agonists into targeted intracellular responses. Although the responses can vary depending on the category of G-proteins activated by a particular receptor, responses were also found to be triggered by interactions of the receptor with β-arrestins. It was subsequently discovered that for the same receptor molecule (e.g., the β-adrenergic receptor), some agonists have a propensity to specifically favor responses by G-proteins, others by β-arrestins, as has now been extensively studied. This feature of the GPCR system is known as biased agonism and is subject to various interpretations, including agonist-induced conformational change versus selective stabilization of preexisting active conformations. Here, we explore a complete allosteric framework for biased agonism based on alternative preexisting conformations that bind more strongly, but nonexclusively, either G-proteins or β-arrestins. The framework incorporates reciprocal effects among all interacting molecules. As a result, G-proteins and β-arrestins are in steric competition for binding to the cytoplasmic surface of either the G-protein-favoring or β-arrestin-favoring GPCR conformation. Moreover, through linkage relations, the strength of the interactions of G-proteins or β-arrestins with the corresponding active conformation potentiates the apparent affinity for the agonist, effectively equating these two proteins to allosteric modulators. The balance between response alternatives can also be influenced by the physiological concentrations of either G-proteins or β-arrestins, as well as by phosphorylation or interactions with positive or negative allosteric modulators. The nature of the interactions in the simulations presented suggests novel experimental tests to distinguish more fully among alternative mechanisms. PMID:27602718
Compensation Method for Die Shift Caused by Flow Drag Force in Wafer-Level Molding Process
Directory of Open Access Journals (Sweden)
Simo Yeon
2016-05-01
Full Text Available Wafer-level packaging (WLP is a next-generation semiconductor packaging technology that is important for realizing high-performance and ultra-thin semiconductor devices. However, the molding process, which is a part of the WLP process, has various problems such as a high defect rate and low predictability. Among the various defect factors, the die shift primarily determines the quality of the final product; therefore, predicting the die shift is necessary to achieve high-yield production in WLP. In this study, the die shift caused by the flow drag force of the epoxy molding compound (EMC is evaluated from the die shift of a debonded molding wafer. Experimental and analytical methods were employed to evaluate the die shift occurring during each stage of the molding process and that resulting from the geometrical changes after the debonding process. The die shift caused by the EMC flow drag force is evaluated from the data on die movements due to thermal contraction/expansion and warpage. The relationship between the die shift and variation in the die gap is determined through regression analysis in order to predict the die shift due to the flow drag force. The results can be used for die realignment by predicting and compensating for the die shift.
Validation of a method to predict hammer speed from cable force
Institute of Scientific and Technical Information of China (English)
Sara M. Brice; Kevin F. Ness; Doug Rosemond
2015-01-01
Purpose: The purpose of this study was to develop and validate a method that would facilitate immediate feedback on linear hammer speed during training. Methods:Three-dimensional hammer head positional data were measured and used to calculate linear speed (calculated speed) and cable force. These data were used to develop two linear regression models (shifted and non-shifted) that would allow prediction of hammer speed from measured cable force data (predicted speed). The accuracy of the two models was assessed by comparing the predicted and calculated speeds. Averages of the coefficient of multiple correlation (CMC) and the root mean square (RMS) of the difference between the predicted and calculated speeds for each throw of each participant were used to assess the level of accuracy of the predicted speeds. Results:Both regression models had high CMC values (0.96 and 0.97) and relatively low RMS values (1.27 m/s and 1.05 m/s) for the non-shifted and shifted models, respectively. In addition, the average percentage differences between the predicted and calculated speeds were 6.6%and 4.7%for the non-shifted and shifted models, respectively. The RMS differences between release speeds attained via the two regression models and those attained via three-dimensional positional data were also computed. The RMS differences between the predicted and calculated release speeds were 0.69 m/s and 0.46 m/s for the non-shifted and shifted models, respectively. Conclusion:This study successfully derived and validated a method that allows prediction of linear hammer speed from directly measured cable force data. Two linear regression models were developed and it was found that either model would be capable of predicting accurate speeds. However, data predicted using the shifted regression model were more accurate.
Measuring nonlocal Lagrangian peak bias
Biagetti, Matteo; Desjacques, Vincent; Paranjape, Aseem
2013-01-01
In the Lagrangian approach to halo clustering, nonlocal bias can be generated either in the initial conditions or by the subsequent gravitational motions. Here, we investigate nonlocal Lagrangian bias contributions involving gradients of the linear density field, for which we have predictions from the excursion set peak formalism. We reformulate this approach in order to explicitly take into account the variable describing the crossing of the collapse barrier. This enables us to write down a bias expansion which includes all the bias terms, including the nonlocal ones. Having checked that the model furnishes a reasonable fit to the halo mass function, we extend the 1-point cross-correlation technique of Musso, Paranjape & Sheth (2012) to bias contributions that are chi-squared distributed. We validate the method with numerical realizations of peaks of Gaussian random fields before applying it to N-body simulations. We focus on the lowest (quadratic) order nonlocal bias factors predicted by the excursion s...
Theoretical investigation of exchange bias
Institute of Scientific and Technical Information of China (English)
Xiong Zhi-Jie; Wang Huai-Yu; Ding Ze-Jun
2007-01-01
The exchange bias of bilayer magnetic films consisting of ferromagnetic (FM) and antiferromagnetic (AFM) layers in an uncompensated case is studied by use of the many-body Green's function method of quantum statistical theory.The effects of the layer thickness and temperature and the interfacial coupling strength on the exchange bias HE are investigated. The dependence of the exchange bias HE on the FM layer thickness and temperature is qualitatively in agreement with experimental results. When temperature varies, both the coercivity HC and HE decrease with the temperature increasing. For each FM thickness, there exists a least AFM thickness in which the exchange bias occurs,which is called pinning thickness.
DEFF Research Database (Denmark)
Fennema-Notestine, Christine; Ozyurt, I Burak; Clark, Camellia P;
2006-01-01
Extractor (BSE, Sandor and Leahy [1997] IEEE Trans Med Imag 16:41-54; Shattuck et al. [2001] Neuroimage 13:856-876) to manually stripped images. The methods were applied to uncorrected and bias-corrected datasets; Legacy and Contemporary T1-weighted image sets; and four diagnostic groups (depressed......, Alzheimer's, young and elderly control). To provide a criterion for outcome assessment, two experts manually stripped six sagittal sections for each dataset in locations where brain and nonbrain tissue are difficult to distinguish. Methods were compared on Jaccard similarity coefficients, Hausdorff...
Study on the AFM Force Spectroscopy method for elastic modulus measurement of living cells
Demichelis, A.; Pavarelli, S.; Mortati, L.; Sassi, G.; Sassi, M.
2013-09-01
The cell elasticity gives information about its pathological state and metastatic potential. The aim of this paper is to study the AFM Force Spectroscopy technique with the future goal of realizing a reference method for accurate elastic modulus measurement in the elasticity range of living cells. This biological range has not been yet explored with a metrological approach. Practical hints are given for the realization of a Sylgard elasticity scale. Systematic effects given by the sample curing thickness and nanoindenter geometry have been found with regards of the measured elastic modulus. AFM measurement reproducibility better than 20% is obtained in the entire investigated elastic modulus scale of 101 - 104 kPa.
Parameter estimation of social forces in pedestrian dynamics models via a probabilistic method.
Corbetta, Alessandro; Muntean, Adrian; Vafayi, Kiamars
2015-04-01
Focusing on a specific crowd dynamics situation, including real life experiments and measurements, our paper targets a twofold aim: (1) we present a Bayesian probabilistic method to estimate the value and the uncertainty (in the form of a probability density function) of parameters in crowd dynamic models from the experimental data; and (2) we introduce a fitness measure for the models to classify a couple of model structures (forces) according to their fitness to the experimental data, preparing the stage for a more general model-selection and validation strategy inspired by probabilistic data analysis. Finally, we review the essential aspects of our experimental setup and measurement technique.
Efficient Methods for Handling Long-Range Forces in Particle-Particle Simulations
Fangohr, H; Cox, S J; De Groot, R A; Daniell, G J; Fangohr, Hans; Price, Andrew R.; Cox, Simon J.; Groot, Peter A.J. de; Daniell, Geoffrey J.
2000-01-01
A number of problems arise when long-range forces, such as those governed by Bessel functions, are used in particle-particle simulations. If a simple cut-off for the interaction is used, the system may find an equilibrium configuration at zero temperature that is not a regular lattice yet has an energy lower than the theoretically predicted minimum for the physical system. We demonstrate two methods to overcome these problems in Monte Carlo and molecular dynamics simulations. The first uses a smoothed potential to truncate the interaction in a single unit cell: this is appropriate for phenomenological characterisations, but may be applied to any potential. The second is a new method for summing the unmodified potential in an infinitely tiled periodic system, which is in excess of 20,000 times faster than previous naive methods which add periodic images in shells of increasing radius: this is suitable for quantitative studies. Finally we show that numerical experiments which do not handle the long-range force ...
IMPROVED FABRICATION METHOD FOR CARBON NANOTUBE PROBE OF ATOMIC FORCE MICROSCOPY(AFM)
Institute of Scientific and Technical Information of China (English)
XU Zongwei; DONG Shen; GUO Liqiu; ZHAO Qingliang
2006-01-01
An improved arc discharge method is developed to fabricate carbon nanotube probe of atomic force microscopy (AFM) here. First, silicon probe and carbon nanotube are manipulated under an optical microscope by two high precision microtranslators. When silicon probe and carbon nanotube are very close, several tens voltage is applied between them. And carbon nanotube is divided and attached to the end of silicon probe, which mainly due to the arc welding function.Comparing with the arc discharge method before, the new method here needs no coat silicon probe with metal film in advance, which can greatly reduce the fabrication's difficulty. The fabricated carbon nanotube probe shows good property of higher aspect ratio and can more accurately reflect the true topography of silicon grating than silicon probe. Under the same image drive force, carbon nanotube probe had less indentation depth on soft triblock copolymer sample than silicon probe. This showed that carbon nanotube probe has lower spring constant and less damage to the scan sample than silicon probe.
A body-force based method to generate supersonic equilibrium turbulent boundary layer profiles
Waindim, M.; Gaitonde, D. V.
2016-01-01
We further develop a simple counterflow body force-based approach to generate an equilibrium spatially developing turbulent boundary layer suitable for Direct Numerical Simulations (DNS) or Large Eddy Simulations (LES) of viscous-inviscid interactions. The force essentially induces a small separated region in an incoming specified laminar boundary layer. The resulting unstable shear layer then transitions and breaks down to yield the desired unsteady profile. The effects of wall thermal conditions are explored to demonstrate the capability of the method for both fixed wall and adiabatic wall conditions. We then describe an efficient method to select parameters that ensure transition by examining precursor signatures using generalized stability variables. These precursors are shown to be evident in a computational domain spanning only a small region around the trip and can also be detected using 2D simulations. Finally, the method is tested for different Mach numbers ranging from 1.7 to 2.9, with emphasis on flow field surveys, Reynolds stresses, and energy spectra. These results provide guidance on boundary conditions for desired boundary layer thickness at each Mach number. The consequences of using a much lower Reynolds number in computation relative to experiment are evident at the higher Mach number, where a self sustaining turbulent boundary layer is more difficult to obtain.
Characterization of single-crystal sapphire substrates by X-ray methods and atomic force microscopy
International Nuclear Information System (INIS)
The possibility of characterizing a number of practically important parameters of sapphire substrates by X-ray methods is substantiated. These parameters include wafer bending, traces of an incompletely removed damaged layer that formed as a result of mechanical treatment (scratches and marks), surface roughness, damaged layer thickness, and the specific features of the substrate real structure. The features of the real structure of single-crystal sapphire substrates were investigated by nondestructive methods of double-crystal X-ray diffraction and plane-wave X-ray topography. The surface relief of the substrates was investigated by atomic force microscopy and X-ray scattering. The use of supplementing analytical methods yields the most complete information about the structural inhomogeneities and state of crystal surface, which is extremely important for optimizing the technology of substrate preparation for epitaxy.
Measuring the loss tangent of polymer materials with atomic force microscopy based methods
International Nuclear Information System (INIS)
Atomic force microscopy (AFM) quantitatively maps viscoelastic parameters of polymers on the nanoscale by several methods. The loss tangent, the ratio between dissipated and stored energy, was measured on a blend of thermoplastic polymer materials by a dynamic contact method, contact resonance, and by a recently developed loss tangent measurement by amplitude modulation AFM. Contact resonance measurements were performed both with dual AC resonance tracking and band excitation (BE), allowing for a reference-free measurement of the loss tangent. Amplitude modulation AFM was performed where a recent interpretation of the phase signal under certain operating conditions allows for the loss tangent to be calculated. The loss tangent measurements were compared with values expected from time–temperature superposed frequency-dependent dynamical mechanical curves of materials and reveal that the loss tangents determined from the BE contact resonance method provide the most accurate values. (paper)
Cognitive biases and language universals
Baronchelli, Andrea; Puglisi, Andrea
2013-01-01
Language universals have been longly attributed to an innate Universal Grammar. An alternative explanation states that linguistic universals emerged independently in every language in response to shared cognitive, though non language-specific, biases. A computational model has recently shown how this could be the case, focusing on the paradigmatic example of the universal properties of color naming patterns, and producing results in accurate agreement with the experimental data. Here we investigate thoroughly the role of a cognitive bias in the framework of this model. We study how, and to what extent, the structure of the bias can influence the corresponding linguistic universal patterns. We show also that the cultural history of a group of speakers introduces population-specific constraints that act against the uniforming pressure of the cognitive bias, and we clarify the interplay between these two forces. We believe that our simulations can help to shed light on the possible mechanisms at work in the evol...
Bharathy, P. Vijai; Nataraj, D.; Chu, Paul K.; Wang, Huaiyu; Yang, Q.; Kiran, M. S. R. N.; Silvestre-Albero, J.; Mangalaraj, D.
2010-10-01
Amorphous diamond like carbon (DLC) and titanium incorporated diamond like carbon (Ti-DLC) thin films were deposited by using reactive-biased target ion beam deposition method. The effects of Ti incorporation and target bias voltage on the microstructure and mechanical properties of the as-deposited films were investigated by means of X-ray photoelectron spectroscopy, Raman spectroscopy, transmission electron microscopy and nano-indentation. It was found that the Ti content in Ti-DLC films gets increased with increasing target bias voltage. At about 4.2 at.% of Ti, uniform sized well dispersed nanocrystals were seen in the DLC matrix. Using FFT analysis, a facility available in the TEM, it was found that the nanocrystals are in cubic TiC phase. Though at the core, the incorporated Ti atoms react with carbon to form cubic TiC; most of the surface exposed Ti atoms were found to react with the atmospheric oxygen to form weakly bonded Ti-O. The presence of TiC nanocrystals greatly modified the sp 3/sp 2 hybridized bonding ratio and is reflected in mechanical hardness of Ti-DLC films. These films were then tested for their biocompatibility by an invitro cell culturing test. Morphological observation and the cell proliferation test have demonstrated that the human osteoblast cells well attach and proliferate on the surface of Ti incorporated DLC films, suggesting possible applications in bone related implant coatings.
Directory of Open Access Journals (Sweden)
J. G. Hemann
2008-02-01
Full Text Available A Positive Matrix Factorization receptor model for aerosol pollution source apportionment was fit to a synthetic dataset simulating one year of daily measurements of ambient PM_{2.5} concentrations, comprised of 39 chemical species from nine pollutant sources. A novel method was developed to estimate model fit uncertainty and bias at the daily time scale, as related to factor contributions. A balanced bootstrap is used to create replicate datasets, with the same model then fit to the data. Neural networks are trained to classify factors based upon chemical profiles, as opposed to correlating contribution time series, and this classification is used to align factor orderings across results associated with the replicate datasets. Factor contribution uncertainty is assessed from the distribution of results associated with each factor. Comparing modeled factors with input factors used to create the synthetic data assesses bias. The results indicate that variability in factor contribution estimates does not necessarily encompass model error: contribution estimates can have small associated variability yet also be very biased. These results are likely dependent on characteristics of the data.
Directory of Open Access Journals (Sweden)
J. G. Hemann
2009-01-01
Full Text Available A Positive Matrix Factorization receptor model for aerosol pollution source apportionment was fit to a synthetic dataset simulating one year of daily measurements of ambient PM_{2.5} concentrations, comprised of 39 chemical species from nine pollutant sources. A novel method was developed to estimate model fit uncertainty and bias at the daily time scale, as related to factor contributions. A circular block bootstrap is used to create replicate datasets, with the same receptor model then fit to the data. Neural networks are trained to classify factors based upon chemical profiles, as opposed to correlating contribution time series, and this classification is used to align factor orderings across the model results associated with the replicate datasets. Factor contribution uncertainty is assessed from the distribution of results associated with each factor. Comparing modeled factors with input factors used to create the synthetic data assesses bias. The results indicate that variability in factor contribution estimates does not necessarily encompass model error: contribution estimates can have small associated variability across results yet also be very biased. These findings are likely dependent on characteristics of the data.
Energy Technology Data Exchange (ETDEWEB)
Bharathy, P. Vijai [Thin Films and Nanomaterials Lab, School of Physical Sciences, Bharathiar University, Coimbatore 641046 (India); Department of Mechanical Engineering, University of Saskatchewan, Saskatoon (Canada); Nataraj, D., E-mail: de.natraj@gmail.com [Thin Films and Nanomaterials Lab, School of Physical Sciences, Bharathiar University, Coimbatore 641046 (India); Chu, Paul K.; Wang, Huaiyu [Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon (Hong Kong); Yang, Q. [Department of Mechanical Engineering, University of Saskatchewan, Saskatoon (Canada); Kiran, M.S.R.N. [School of Physics, University of Hyderabad, Hyderabad, Andra Pradesh (India); Silvestre-Albero, J. [Laboratorio de Materiales Avanzados, Departmento de Quimica Inorganica, Universidad de Alicante, Ap 99, E-03080 Alicante (Spain); Mangalaraj, D. [Thin Films and Nanomaterials Lab, School of Physical Sciences, Bharathiar University, Coimbatore 641046 (India)
2010-10-15
Amorphous diamond like carbon (DLC) and titanium incorporated diamond like carbon (Ti-DLC) thin films were deposited by using reactive-biased target ion beam deposition method. The effects of Ti incorporation and target bias voltage on the microstructure and mechanical properties of the as-deposited films were investigated by means of X-ray photoelectron spectroscopy, Raman spectroscopy, transmission electron microscopy and nano-indentation. It was found that the Ti content in Ti-DLC films gets increased with increasing target bias voltage. At about 4.2 at.% of Ti, uniform sized well dispersed nanocrystals were seen in the DLC matrix. Using FFT analysis, a facility available in the TEM, it was found that the nanocrystals are in cubic TiC phase. Though at the core, the incorporated Ti atoms react with carbon to form cubic TiC; most of the surface exposed Ti atoms were found to react with the atmospheric oxygen to form weakly bonded Ti-O. The presence of TiC nanocrystals greatly modified the sp{sup 3}/sp{sup 2} hybridized bonding ratio and is reflected in mechanical hardness of Ti-DLC films. These films were then tested for their biocompatibility by an invitro cell culturing test. Morphological observation and the cell proliferation test have demonstrated that the human osteoblast cells well attach and proliferate on the surface of Ti incorporated DLC films, suggesting possible applications in bone related implant coatings.
International Nuclear Information System (INIS)
Amorphous diamond like carbon (DLC) and titanium incorporated diamond like carbon (Ti-DLC) thin films were deposited by using reactive-biased target ion beam deposition method. The effects of Ti incorporation and target bias voltage on the microstructure and mechanical properties of the as-deposited films were investigated by means of X-ray photoelectron spectroscopy, Raman spectroscopy, transmission electron microscopy and nano-indentation. It was found that the Ti content in Ti-DLC films gets increased with increasing target bias voltage. At about 4.2 at.% of Ti, uniform sized well dispersed nanocrystals were seen in the DLC matrix. Using FFT analysis, a facility available in the TEM, it was found that the nanocrystals are in cubic TiC phase. Though at the core, the incorporated Ti atoms react with carbon to form cubic TiC; most of the surface exposed Ti atoms were found to react with the atmospheric oxygen to form weakly bonded Ti-O. The presence of TiC nanocrystals greatly modified the sp3/sp2 hybridized bonding ratio and is reflected in mechanical hardness of Ti-DLC films. These films were then tested for their biocompatibility by an invitro cell culturing test. Morphological observation and the cell proliferation test have demonstrated that the human osteoblast cells well attach and proliferate on the surface of Ti incorporated DLC films, suggesting possible applications in bone related implant coatings.
A Spanish continuous voluntary web survey: sample bias, weighting and efficiency
Pedraza,, I.; Tijdens, K.; Muñoz de Bustillo, R.; Steinmetz, S
2010-01-01
Using micro data from a continuous volunteer web survey (CVWS), the WageIndicator (WI), this paper firstly analyses the type of bias that such a survey method produces. Secondly, following a «modelbased » approach, two alternative data weighting methodologies are implemented. Thirdly, in order to test whether weighting corrects the bias, thus making it possible to obtain conclusions applicable to the whole labour force, the efficiency of the weighting methodologies is evaluated. Since the Wag...
2004-01-01
The grant closure report is organized in the following four chapters: Chapter describes the two research areas Design optimization and Solid mechanics. Ten journal publications are listed in the second chapter. Five highlights is the subject matter of chapter three. CHAPTER 1. The Design Optimization Test Bed CometBoards. CHAPTER 2. Solid Mechanics: Integrated Force Method of Analysis. CHAPTER 3. Five Highlights: Neural Network and Regression Methods Demonstrated in the Design Optimization of a Subsonic Aircraft. Neural Network and Regression Soft Model Extended for PX-300 Aircraft Engine. Engine with Regression and Neural Network Approximators Designed. Cascade Optimization Strategy with Neural network and Regression Approximations Demonstrated on a Preliminary Aircraft Engine Design. Neural Network and Regression Approximations Used in Aircraft Design.
Wave system fitting: A new method for force measurements in shock tunnels with long test duration
Luo, Changtong; Wang, Yunpeng; Wang, Chun; Jiang, Zonglin
2015-10-01
Force measurements in shock tunnels are difficult due to the existence of vibrations excited by a sudden aerodynamic loading. Accelerometer inertia compensation could reduce its negative effect to some extent, but has inherent problems. A new signal decomposition method, wave system fitting (WSF), is proposed to remove vibration waves of low frequency. The WSF is accelerometer-free. It decomposes the balance signal and can separate vibration waves without the influence on the DC component, and it does work no matter the cycle of the sample signal is complete or not. As a standard signal post-processing tool in JF-12, the application results show that it works reliably with high accuracy, and it can also explain puzzling signals encountered in JF-12. WSF method is especially useful and irreplaceable whenever only a few cycles of a periodic signal could be obtained, as is usual for shock tunnels.
Yuan, Jianping; Zhu, Zhanxia; Ming, Zhenfeng; Luo, Qiuyue
2015-07-01
This paper proposes an innovative method for simulating space microgravity effects. The new approach combines the neutral buoyancy and the electromagnetic force on the tested-body to balance the gravity and simulate the microgravity effects. In the paper, we present in some detail the magnetism-buoyancy hybrid microgravity simulation system, its components, functions and verification. We describe some key techniques such as ground-space similarity, the homogenization of electromagnetic field, the precise control of microgravity effects in dynamic environment, measurement in the hybrid suspension system. With this innovative microgravity simulation system, we prove through experiments and tests that our innovative method is feasible and effective and that the simulation fidelity is even higher than the neutral buoyancy system.
Application of Base Force Element Method to Mesomechanics Analysis for Recycled Aggregate Concrete
Directory of Open Access Journals (Sweden)
Yijiang Peng
2013-01-01
Full Text Available The base force element method (BFEM on potential energy principle is used to analyze recycled aggregate concrete (RAC on mesolevel. The model of BFEM with triangular element is derived. The recycled aggregate concrete is taken as five-phase composites consisting of natural coarse aggregate, new mortar, new interfacial transition zone (ITZ, old mortar, and old ITZ on meso-level. The random aggregate model is used to simulate the mesostructure of recycled aggregate concrete. The mechanics properties of uniaxial compression and tension tests for RAC are simulated using the BFEM, respectively. The simulation results agree with the test results. This research method is a new way for investigating fracture mechanism and numerical simulation of mechanics properties for recycled aggregate concrete.
International Nuclear Information System (INIS)
Structural health monitoring (SHM) consists of the continuous or periodic measurement of structural parameters and their analysis with the aim of deducing information about the performance and health condition of a structure. The significant increase in the construction of prestressed concrete bridges motivated this research on an SHM method for the on-site determination of the distribution of prestressing forces along prestressed concrete beam structures. The estimation of the distribution of forces is important as it can give information regarding the overall performance and structural integrity of the bridge. An inadequate transfer of the designed prestressing forces to the concrete cross-section can lead to a reduced capacity of the bridge and consequently malfunction or failure at lower loads than predicted by design. This paper researches a universal method for the determination of the distribution of prestressing forces along concrete beam structures at the time of transfer of the prestressing force (e.g., at the time of prestressing or post-tensioning). The method is based on the use of long-gauge fiber optic sensors, and the sensor network is similar (practically identical) to the one used for damage identification. The method encompasses the determination of prestressing forces at both healthy and cracked cross-sections, and for the latter it can yield information about the condition of the cracks. The method is validated on-site by comparison to design forces through the application to two structures: (1) a deck-stiffened arch and (2) a curved continuous girder. The uncertainty in the determination of prestressing forces was calculated and the comparison with the design forces has shown very good agreement in most of the structures’ cross-sections, but also helped identify some unusual behaviors. The method and its validation are presented in this paper. (papers)
Forced degradation of nepafenac: Development and validation of stability indicating UHPLC method.
Runje, Mislav; Babić, Sandra; Meštrović, Ernest; Nekola, Irena; Dujmić-Vučinić, Željka; Vojčić, Nina
2016-05-10
This paper presents stability study of the nonsteroidal anti-inflammatory drug (NSAID) nepafenac. In order to investigate stability of nepafenac, it was subjected to forced degradation under different stress conditions: acid and base hydrolysis, oxidation, humidity, heat and light. A novel stability indicating reverse phase ultra high performance liquid chromatographic (UHPLC) method coupled to ultraviolet detector has been developed to separate nepafenac and all related compounds (2-aminobenzophenone, Cl-thionepafenac, thionepafenac, Cl-nepafenac, hydroxy-nepafenac, and cyclic-nepafenac). Efficient chromatographic separation was achieved on a Waters Acquity BEH C18 stationary phase with a gradient elution. Quantification was carried out at 235 nm at a flow rate of 0.6 mL/min(-1). The resolution between nepafenac and six potential impurities is found to be greater than 2.0. The developed method was validated with respect to specificity, LOD, LOQ, linearity, precision, accuracy and robustness. The r(2) values for nepafenac and six potential impurities were all greater than 0.999. The developed method is capable to detect impurities of nepafenac at a level of 0.005% with respect to test concentration of 1.0mg/mL. Significant degradation is observed in acid, base and oxidative degradation conditions and degradation products (DPs) were identified using mass spectrometry analysis; two of them were found to be a known process related impurities (hydroxy- and cyclic-nepafenac) whereas four degradation products were identified as new degradation impurities. The forced degradation samples were assayed against a qualified reference standard and the mass balance was found to be close to 99.5%. PMID:26871279
Multi-Sphere Method for modeling spacecraft electrostatic forces and torques
Stevenson, Daan; Schaub, Hanspeter
2013-01-01
The use of electrostatic (Coulomb) actuation for formation flying is attractive because non-renewable fuel reserves are not depleted and plume impingement issues are avoided. Prior analytical electrostatic force models used for Coulomb formations assume spherical spacecraft shapes, which include mutual capacitance and induced effects. However, this framework does not capture any orientation-dependent forces or torques on generic spacecraft geometries encountered during very close operations and docking scenarios. The Multi-Sphere Method (MSM) uses a collection of finite spheres to represent a complex shape and analytically approximate the Coulomb interaction with other charged bodies. Finite element analysis software is used as a truth model to determine the optimal sphere locations and radii. The model is robust to varying system parameters such as prescribed voltages and external shape size. Using the MSM, faster-than-realtime electrostatic simulation of six degree of freedom relative spacecraft motion is feasible, which is crucial for the development of robust relative position and orientation control algorithms in local space situational awareness applications. To demonstrate this ability, the rotation of a cylindrical craft in deep space is simulated, while charge control from a neighboring spacecraft is used to de-spin the object. Using a 1 m diameter craft separated by 10 m from a 3 by 1 m cylindrical craft in deep space, a 2 °/s initial rotation rate can be removed from the cylinder within 3 days, using electric potentials up to 30 kV.
Indian Academy of Sciences (India)
A NASSOUR
2016-09-01
In the present paper, an empirical embedded atom method (EAM) potential for gold–silicon (Au–Si) is developed by fitting to ab initio force (the ‘force matching’ method) and experimental data. The force database is generated within ab initio molecular dynamics (AIMD). The database includes liquid phase at various temperatures. Classical molecular dynamics simulations are performed to examine structural, coordination numbers, structure factors and dynamic properties of Au$_{81}$Si$_{19}$ alloy, with the interaction described via EAM model. The results are in good agreement with AIMD simulations and experimental data.
Directory of Open Access Journals (Sweden)
Lee Wah
2008-09-01
Full Text Available Abstract Background Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utilize random primers rather than specific primers for the RT-PCR step, bias inherent in random PCR amplification becomes a serious problem that causes large inaccuracies in hybridization signals. Results In this paper, we study how the efficiency of random PCR amplification affects hybridization signals. We describe a model that predicts the amplification efficiency of a given random primer on a target viral genome. The prediction allows us to filter false-negative probes of the genome that lie in regions of poor random PCR amplification and improves the accuracy of pathogen detection. Subsequently, we propose LOMA, an algorithm to generate random primers that have good amplification efficiency. Wet-lab validation showed that the generated random primers improve the amplification efficiency significantly. Conclusion The blind use of a random primer with attached universal tag (random-tagged primer in a PCR reaction on a pathogen sample may not lead to a successful amplification. Thus, the design of random-tagged primers is an important consideration when performing PCR.
Nuclear spin imaging with hyperpolarized nuclei created by brute force method
Tanaka, Masayoshi; Kunimatsu, Takayuki; Fujiwara, Mamoru; Kohri, Hideki; Ohta, Takeshi; Utsuro, Masahiko; Yosoi, Masaru; Ono, Satoshi; Fukuda, Kohji; Takamatsu, Kunihiko; Ueda, Kunihiro; Didelez, Jean-P.; Prossati, Giorgio; de Waard, Arlette
2011-05-01
We have been developing a polarized HD target for particle physics at the SPring-8 under the leadership of the RCNP, Osaka University for the past 5 years. Nuclear polarizaton is created by means of the brute force method which uses a high magnetic field (~17 T) and a low temperature (~ 10 mK). As one of the promising applications of the brute force method to life sciences we started a new project, "NSI" (Nuclear Spin Imaging), where hyperpolarized nuclei are used for the MRI (Magnetic Resonance Imaging). The candidate nuclei with spin ½hslash are 3He, 13C, 15N, 19F, 29Si, and 31P, which are important elements for the composition of the biomolecules. Since the NMR signals from these isotopes are enhanced by orders of magnitudes, the spacial resolution in the imaging would be much more improved compared to the practical MRI used so far. Another advantage of hyperpolarized MRI is that the MRI is basically free from the radiation, while the problems of radiation exposure caused by the X-ray CT or PET (Positron Emission Tomography) cannot be neglected. In fact, the risk of cancer for Japanese due to the radiation exposure through these diagnoses is exceptionally high among the advanced countries. As the first step of the NSI project, we are developing a system to produce hyperpolarized 3He gas for the diagnosis of serious lung diseases, for example, COPD (Chronic Obstructive Pulmonary Disease). The system employs the same 3He/4He dilution refrigerator and superconducting solenoidal coil as those used for the polarized HD target with some modification allowing the 3He Pomeranchuk cooling and the following rapid melting of the polarized solid 3He to avoid the depolarization. In this report, the present and future steps of our project will be outlined with some latest experimental results.
Comparison of an EMG-based and a stress-based method to predict shoulder muscle forces.
Engelhardt, Christoph; Malfroy Camine, Valérie; Ingram, David; Müllhaupt, Philippe; Farron, Alain; Pioletti, Dominique; Terrier, Alexandre
2015-01-01
The estimation of muscle forces in musculoskeletal shoulder models is still controversial. Two different methods are widely used to solve the indeterminacy of the system: electromyography (EMG)-based methods and stress-based methods. The goal of this work was to evaluate the influence of these two methods on the prediction of muscle forces, glenohumeral load and joint stability after total shoulder arthroplasty. An EMG-based and a stress-based method were implemented into the same musculoskeletal shoulder model. The model replicated the glenohumeral joint after total shoulder arthroplasty. It contained the scapula, the humerus, the joint prosthesis, the rotator cuff muscles supraspinatus, subscapularis and infraspinatus and the middle, anterior and posterior deltoid muscles. A movement of abduction was simulated in the plane of the scapula. The EMG-based method replicated muscular activity of experimentally measured EMG. The stress-based method minimised a cost function based on muscle stresses. We compared muscle forces, joint reaction force, articular contact pressure and translation of the humeral head. The stress-based method predicted a lower force of the rotator cuff muscles. This was partly counter-balanced by a higher force of the middle part of the deltoid muscle. As a consequence, the stress-based method predicted a lower joint load (16% reduced) and a higher superior-inferior translation of the humeral head (increased by 1.2 mm). The EMG-based method has the advantage of replicating the observed cocontraction of stabilising muscles of the rotator cuff. This method is, however, limited to available EMG measurements. The stress-based method has thus an advantage of flexibility, but may overestimate glenohumeral subluxation.
Directory of Open Access Journals (Sweden)
Domenico Fuoco
2012-03-01
Full Text Available In order to study and develop an economical solution to environmental pollution in water, a wide variety of materials have been investigated. Natural zeolites emerge from that research as the best in class of this category. Zeolites are natural materials which are relatively abundant and non biodegradable, economical and serve to perform processes of environmental remediation. This paper contains a full description of a new method to characterize the superficial properties of natural zeolites of exotic provenience (Caribbean Islets with atomic force microscopy (AFM. AFM works with the simplicity of the optical microscope and the high resolution typical of a transmission electron microscope (TEM. If the sample is conductive, structural information of mesoporous material is obtained using scanning and transmission electron microscopy (SEM and TEM, otherwise the sample has to be processed through the grafitation technique, but this procedure induces errors of topography. Therefore, the existing AFM method, to observe zeolite powders, is made in a liquid cell-head scanner. This work confirms that it is possible to use an ambient air-head scanner to obtain a new kind of microtopography. Once optimized, this new method will allow investigation of organic micelles, a very soft nanostructure of cetyltriammonium bromide (CTAB, upon an inorganic surface such as natural zeolites. The data also demonstrated some correlation between SEM microphotographies and AFM 3D images.
Identifying a robust method to build RCMs ensemble as climate forcing for hydrological impact models
Olmos Giménez, P.; García Galiano, S. G.; Giraldo-Osorio, J. D.
2016-06-01
The regional climate models (RCMs) improve the understanding of the climate mechanism and are often used as climate forcing to hydrological impact models. Rainfall is the principal input to the water cycle, so special attention should be paid to its accurate estimation. However, climate change projections of rainfall events exhibit great divergence between RCMs. As a consequence, the rainfall projections, and the estimation of uncertainties, are better based in the combination of the information provided by an ensemble approach from different RCMs simulations. Taking into account the rainfall variability provided by different RCMs, the aims of this work are to evaluate the performance of two novel approaches based on the reliability ensemble averaging (REA) method for building RCMs ensembles of monthly precipitation over Spain. The proposed methodologies are based on probability density functions (PDFs) considering the variability of different levels of information, on the one hand of annual and seasonal rainfall, and on the other hand of monthly rainfall. The sensitivity of the proposed approaches, to two metrics for identifying the best ensemble building method, is evaluated. The plausible future scenario of rainfall for 2021-2050 over Spain, based on the more robust method, is identified. As a result, the rainfall projections are improved thus decreasing the uncertainties involved, to drive hydrological impacts models and therefore to reduce the cumulative errors in the modeling chain.
Efficient evaluation of the Coulomb force in the Gaussian and finite-element Coulomb method
Kurashige, Yuki; Nakajima, Takahito; Sato, Takeshi; Hirao, Kimihiko
2010-06-01
We propose an efficient method for evaluating the Coulomb force in the Gaussian and finite-element Coulomb (GFC) method, which is a linear-scaling approach for evaluating the Coulomb matrix and energy in large molecular systems. The efficient evaluation of the analytical gradient in the GFC is not straightforward as well as the evaluation of the energy because the SCF procedure with the Coulomb matrix does not give a variational solution for the Coulomb energy. Thus, an efficient approximate method is alternatively proposed, in which the Coulomb potential is expanded in the Gaussian and finite-element auxiliary functions as done in the GFC. To minimize the error in the gradient not just in the energy, the derived functions of the original auxiliary functions of the GFC are used additionally for the evaluation of the Coulomb gradient. In fact, the use of the derived functions significantly improves the accuracy of this approach. Although these additional auxiliary functions enlarge the size of the discretized Poisson equation and thereby increase the computational cost, it maintains the near linear scaling as the GFC and does not affects the overall efficiency of the GFC approach.
Comparative analysis of methods for determining bite force in the spiny dogfish Squalus acanthias.
Huber, Daniel Robert; Motta, Philip Jay
2004-01-01
Many studies have identified relationships between the forces generated by the cranial musculature during feeding and cranial design. Particularly important to understanding the diversity of cranial form amongst vertebrates is knowledge of the generated magnitudes of bite force because of its use as a measure of ecological performance. In order to determine an accurate morphological proxy for bite force in elasmobranchs, theoretical force generation by the quadratomandibularis muscle of the spiny dogfish Squalus acanthias was modeled using a variety of morphological techniques, and lever-ratio analyses were used to determine resultant bite forces. These measures were compared to in vivo bite force measurements obtained with a pressure transducer during tetanic stimulation experiments of the quadratomandibularis. Although no differences were found between the theoretical and in vivo bite forces measured, modeling analyses indicate that the quadratomandibularis muscle should be divided into its constituent divisions and digital images of the cross-sections of these divisions should be used to estimate cross-sectional area when calculating theoretical force production. From all analyses the maximum bite force measured was 19.57 N. This relatively low magnitude of bite force is discussed with respect to the ecomorphology of the feeding mechanism of S. acanthias to demonstrate the interdependence of morphology, ecology, and behavior in organismal design. PMID:14695686
Nesterov, Vladimir
2009-08-01
A nanonewton force facility, based on a disk-pendulum with electrostatic stiffness reduction and electrostatic force compensation, for the measurement of horizontal forces in the range below 1 µN, is presented. It consists of a measuring system and an identical reference system. Recent experiments with the nanonewton force facility have achieved agreement between an electrostatic force and a gravitational force of 80 nN with an uncertainty of less than 3%. A novel method for measurements of the air (vacuum) permittivity at zero frequencies by means of the nanonewton force facility is presented. First measurements in air show a permittivity of the air ɛ ≈ 8.71 × 10-12 F m-1 with an uncertainty of 3%. From a theoretical analysis, it follows that this method can be used for the measurement of the vacuum permittivity ɛ0 at zero frequencies with a relative uncertainty of about 10-5. The precise measurement of the vacuum permittivity ɛ0 for an electrostatic field would be another test for the correctness of Maxwell's equations.
Verma, Siddhartha; Novati, Guido; Koumoutsakos, Petros
2016-01-01
The distribution of forces on the surface of complex, deforming geometries is an invaluable output of flow simulations. One particular example of such geometries involves self-propelled swimmers. Surface forces can provide significant information about the flow field sensed by the swimmers, and are difficult to obtain experimentally. At the same time, simulations of flow around complex, deforming shapes can be computationally prohibitive when body-fitted grids are used. Alternatively, such simulations may employ penalization techniques. Penalization methods rely on simple Cartesian grids to discretize the governing equations, which are enhanced by a penalty term to account for the boundary conditions. They have been shown to provide a robust estimation of mean quantities, such as drag and propulsion velocity, but the computation of surface force distribution remains a challenge. We present a method for determining flow- induced forces on the surface of both rigid and deforming bodies, in simulations using re-...
DEFF Research Database (Denmark)
Babiker, Hassan; Ding, Ming; Overgaard, Søren
2013-01-01
could be affected by the various quality and quantity of bone in the local environment. Thus, implant ﬁxation in one part might differ from the other part of the implant. This study aimed to investigate the inﬂuence of the sampling method on data evaluation. Material and methods: Titanium alloy implants...
The Adaptive Buffered Force QM/MM method in the CP2K and AMBER software packages
Mones, Letif; Götz, Andreas W; Laino, Teodoro; Walker, Ross C; Leimkuhler, Ben; Csányi, Gábor; Bernstein, Noam
2014-01-01
The implementation and validation of the adaptive buffered force QM/MM method in two popular packages, CP2K and AMBER are presented. The implementations build on the existing QM/MM functionality in each code, extending it to allow for redefinition of the QM and MM regions during the simulation and reducing QM-MM interface errors by discarding forces near the boundary according to the buffered force-mixing approach. New adaptive thermostats, needed by force-mixing methods, are also implemented. Different variants of the method are benchmarked by simulating the structure of bulk water, water autoprotolysis in the presence of zinc and dimethyl-phosphate hydrolysis using various semiempirical Hamiltonians and density functional theory as the QM model. It is shown that with suitable parameters, based on force convergence tests, the adaptive buffered-force QM/MM scheme can provide an accurate approximation of the structure in the dynamical QM region matching the corresponding fully QM simulations, as well as reprod...
Sandage, A; Sandage, Allan
2002-01-01
Please note that this abstract has been shortened from that found in the paper. A brief history is given of the development of the correction for observation selection bias inherent in the calibration of absolute magnitudes using trigonometric parallaxes. As a tutorial to gain an intuitive understanding of several complicated trigonometric bias problems, we study a toy bias model of a parallax catalog which incorporates assumed parallax measuring errors of various severities. The two effects of bias errors on the derived absolute magnitudes are (1) the Lutz-Kelker correction itself that depends on the fractional parallax error and the spatial distribution, and (2) a Malmquist-like `incompleteness' correction of opposite sign due to various apparent magnitude cut-offs as they are progressively imposed on the catalog. The simulations involve 3 million stars spread with varying density distributions in a volume bounded by a radius of 50,000 pc. A fixed absolute magnitude of M_V = +0.6 is used to imitate RR Lyrae...
Venema, Victor; Lindau, Ralf
2016-04-01
In an accompanying talk we show that well-homogenized national dataset warm more than temperatures from global collections averaged over the region of common coverage. In this poster we want to present auxiliary work about possible biases in the raw observations and on how well relative statistical homogenization can remove trend biases. There are several possible causes of cooling biases, which have not been studied much. Siting could be an important factor. Urban stations tend to move away from the centre to better locations. Many stations started inside of urban areas and are nowadays more outside. Even for villages the temperature difference between the centre and edge can be 0.5°C. When a city station moves to an airport, which often happened around WWII, this takes the station (largely) out of the urban heat island. During the 20th century the Stevenson screen was established as the dominant thermometer screen. This screen protected the thermometer much better against radiation than earlier designs. Deficits of earlier measurement methods have artificially warmed the temperatures in the 19th century. Newer studies suggest we may have underestimated the size of this bias. Currently we are in a transition to Automatic Weather Stations. The net global effect of this transition is not clear at this moment. Irrigation on average decreases the 2m-temperature by about 1 degree centigrade. At the same time, irrigation has increased significantly during the last century. People preferentially live in irrigated areas and weather stations serve agriculture. Thus it is possible that there is a higher likelihood that weather stations are erected in irrigated areas than elsewhere. In this case irrigation could lead to a spurious cooling trend. In the Parallel Observations Science Team of the International Surface Temperature Initiative (ISTI-POST) we are studying influence of the introduction of Stevenson screens and Automatic Weather Stations using parallel measurements
Elvarsson, B. P.; Taylor, L.; Trenkel, Verena; Kupca, V.; Stefansson, G.
2014-01-01
Statistical models of marine ecosystems use a variety of data sources to estimate parameters using composite or weighted likelihood functions with associated weighting issues and questions on how to obtain variance estimates. Regardless of the method used to obtain point estimates, a method is required for variance estimation. A bootstrap technique is introduced for the evaluation of uncertainty in such models, taking into account inherent spatial and temporal correlations in the datasets, wh...
Directory of Open Access Journals (Sweden)
Shojiro Miyake
2014-01-01
Full Text Available Diamond-like carbon (DLC films are deposited by bend filtered cathodic vacuum arc (FCVA technique with DC and pulsed bias voltage. The effects of varying bias voltage on nanoindentation and nanowear properties were evaluated by atomic force microscopy. DLC films deposited with DC bias voltage of −50 V exhibited the greatest hardness at approximately 50 GPa, a low modulus of dissipation, low elastic modulus to nanoindentation hardness ratio, and high nanowear resistance. Nanoindentation hardness was positively correlated with the Raman peak ratio Id/Ig, whereas wear depth was negatively correlated with this ratio. These nanotribological properties highly depend on the films’ nanostructures. The tribological properties of the FCVA-DLC films were also investigated using a ball-on-disk test. The average friction coefficient of DLC films deposited with DC bias voltage was lower than that of DLC films deposited with pulse bias voltage. The friction coefficient calculated from the ball-on-disk test was correlated with the nanoindentation hardness in dry conditions. However, under boundary lubrication conditions, the friction coefficient and specific wear rate had little correlation with nanoindentation hardness, and wear behavior seemed to be influenced by other factors such as adhesion strength between the film and substrate.
Meiklejohn, Kelly A; Faircloth, Brant C; Glenn, Travis C; Kimball, Rebecca T; Braun, Edward L
2016-07-01
Rapid evolutionary radiations are expected to require large amounts of sequence data to resolve. To resolve these types of relationships many systematists believe that it will be necessary to collect data by next-generation sequencing (NGS) and use multispecies coalescent ("species tree") methods. Ultraconserved element (UCE) sequence capture is becoming a popular method to leverage the high throughput of NGS to address problems in vertebrate phylogenetics. Here we examine the performance of UCE data for gallopheasants (true pheasants and allies), a clade that underwent a rapid radiation 10-15 Ma. Relationships among gallopheasant genera have been difficult to establish. We used this rapid radiation to assess the performance of species tree methods, using ∼600 kilobases of DNA sequence data from ∼1500 UCEs. We also integrated information from traditional markers (nuclear intron data from 15 loci and three mitochondrial gene regions). Species tree methods exhibited troubling behavior. Two methods [Maximum Pseudolikelihood for Estimating Species Trees (MP-EST) and Accurate Species TRee ALgorithm (ASTRAL)] appeared to perform optimally when the set of input gene trees was limited to the most variable UCEs, though ASTRAL appeared to be more robust than MP-EST to input trees generated using less variable UCEs. In contrast, the rooted triplet consensus method implemented in Triplec performed better when the largest set of input gene trees was used. We also found that all three species tree methods exhibited a surprising degree of dependence on the program used to estimate input gene trees, suggesting that the details of likelihood calculations (e.g., numerical optimization) are important for loci with limited phylogenetic information. As an alternative to summary species tree methods we explored the performance of SuperMatrix Rooted Triple - Maximum Likelihood (SMRT-ML), a concatenation method that is consistent even when gene trees exhibit topological differences
DEFF Research Database (Denmark)
Silcowitz, Morten; Niebe, Sarah Maria; Erleben, Kenny
2009-01-01
n interactive physical simulation, contact forces are applied to prevent rigid bodies from penetrating each other. Accurate contact force determination is a computationally hard problem. Thus, in practice one trades accuracy for performance. The result is visual artifacts such as viscous or damped...
Anker, Richard
1983-01-01
This article discusses the difficulties involved in obtaining accurate labor force data for Third World women, from the point of view of interviewers, respondents, and labor statisticians or economists. Suggestions are then made regarding alternative definitions of the labor force and survey questionnaire structures in order to overcome some of…
The Modeling Method of Forces Action Based on COADL%基于COADL兵力行动建模方法
Institute of Scientific and Technical Information of China (English)
张磊; 朱琳
2011-01-01
According to the desire of forces action modeling,designing a series of modeling language for forces action- COADL (Course Of Action Description Language), from the description of forces action modeling language,giving the outcome of forces action strategy. And as a basis, discussing the method of forces action modeling which based on COADL, concretely including : forces action basic modeling, phase action modeling, course of action modeling and forces action dynamic model.%根据兵力行动建模的需要,设计了一套兵力行动建模语言--COADL (Course Of Action Description Language),通过对兵力行动建模语言的描述,得到了兵力行动策略的产生,并以此为基础,讨论了基于COADL兵力行动的建模方法,具体包括:基本兵力行动建模,阶段行动方案建模,行动过程建模和兵力行动动态模型的构建.
Energy Technology Data Exchange (ETDEWEB)
Maiz, F., E-mail: fethimaiz@gmail.com [University of Cartage, Nabeul Engineering Preparatory Institute, Merazka, 8000 Nabeul (Tunisia); King Khalid University, Faculty of Science, Physics Department, PO Box 9004, Abha 61413 (Saudi Arabia)
2015-04-15
A novel method to calculate the quantum transmission, resonance and eigenvalue energies forming the sub-bands structure of non-symmetrical, non-periodical semiconducting heterostructure potential has been proposed in this paper. The method can be applied on a multilayer system with varying thickness of the layer and effective mass of electrons and holes. Assuming an approximated effective mass and using Bastard's boundary conditions, Schrödinger equation at each media is solved and then using a confirmed recurrence method, the transmission and reflection coefficients and the energy quantification condition are expressed. They are simple combination of coupled equations. Schrödinger's equation solutions are Airy functions or plane waves, depending on the electrical potential energy slope. To illustrate the feasibility of the proposed method, the N barriers – (N−1) wells structure for N=3, 5, 8, 9, 17 and 35 are studied. All results show very good agreements with previously published results obtained from applying different methods on similar systems.
Directory of Open Access Journals (Sweden)
Md. Sharif Hasan
2016-01-01
Full Text Available The aim of our current research was to synthesize some transition metal complexes of Naproxen, determine their physical properties, and examine their relative stability under various conditions. Characterizations of these complexes were done by 1H-NMR, Differential Scanning Calorimetry (DSC, FT-IR, HPLC, and scanning electron microscope (SEM. Complexes were subjected to acidic, basic, and aqueous hydrolysis as well as oxidation, reduction, and thermal degradation. Also the reversed phase high-performance liquid chromatography (RP-HPLC method of Naproxen outlined in USP was verified for the Naproxen-metal complexes, with respect to accuracy, precision, solution stability, robustness, and system suitability. The melting points of the complexes were higher than that of the parent drug molecule suggesting their thermal stability. In forced degradation study, complexes were found more stable than the Naproxen itself in all conditions: acidic, basic, oxidation, and reduction media. All the HPLC verification parameters were found within the acceptable value. Therefore, it can be concluded from the study that the metal complexes of Naproxen can be more stable drug entity and offer better efficacy and longer shelf life than the parent Naproxen.
Comparison of force fields and calculation methods for vibration intervals of isotopic H+3 molecules
International Nuclear Information System (INIS)
This paper reports (a) improved values for low-lying vibration intervals of H+3, H2D+, D2H+, and D+3 calculated using the variational method and Simons--Parr--Finlan representations of the Carney--Porter and Dykstra--Swope ab initio H+3 potential energy surfaces, (b) quartic normal coordinate force fields for isotopic H+3 molecules, (c) comparisons of variational and second-order perturbation theory, and (d) convergence properties of the Lai--Hagstrom internal coordinate vibrational Hamiltonian. Standard deviations between experimental and ab initio fundamental vibration intervals of H+3, H2D+, D2H+, and D+3 for these potential surfaces are 6.9 (Carney--Porter) and 1.2 cm-1 (Dykstra--Swope). The standard deviations between perturbation theory and exact variational fundamentals are 5 and 10 cm-1 for the respective surfaces. The internal coordinate Hamiltonian is found to be less efficient than the previously employed ''t'' coordinate Hamiltonian for these molecules, except in the case of H2D+
Pre-employment screening and health management for safety forces-methods and techniques.
Mostardi, R A; Porterfield, J A; King, S; Urycki, S
1990-01-01
The purpose of this clinical report is to describe the process by which safety forces (police and fire) are tested prior to employment (pre-employment screening) and the periodic evaluations used to maintain such standards. The process began by testing 350 male police volunteers and developing a series of age stratified norms. These norms are used to compare incoming recruits such that candidates of a given age are compared to norms developed from police officers of the same age. The purposes of this report are to describe the clinical tests used in the pre-employment screening, to report the normative data and to describe the methods of comparing data obtained from applicants to the established norms. The proper management of high risk employees through pre-employment screening and intervention programs has been viewed as being necessary both for the individual employee in reducing injury and disease and for the municipality for cost saving purposes. J Orthop Sports Phys Ther 1990;11(9):398-401. PMID:18787271
Numerical Simulation of Recycled Concrete Using Convex Aggregate Model and Base Force Element Method
Directory of Open Access Journals (Sweden)
Yijiang Peng
2016-01-01
Full Text Available By using the Base Force Element Method (BFEM on potential energy principle, a new numerical concrete model, random convex aggregate model, is presented in this paper to simulate the experiment under uniaxial compression for recycled aggregate concrete (RAC which can also be referred to as recycled concrete. This model is considered as a heterogeneous composite which is composed of five mediums, including natural coarse aggregate, old mortar, new mortar, new interfacial transition zone (ITZ, and old ITZ. In order to simulate the damage processes of RAC, a curve damage model was adopted as the damage constitutive model and the strength theory of maximum tensile strain was used as the failure criterion in the BFEM on mesomechanics. The numerical results obtained in this paper which contained the uniaxial compressive strengths, size effects on strength, and damage processes of RAC are in agreement with experimental observations. The research works show that the random convex aggregate model and the BFEM with the curve damage model can be used for simulating the relationship between microstructure and mechanical properties of RAC.
DEFF Research Database (Denmark)
Hasmasan, Adrian Augustin; Busca, Christian; Teodorescu, Remus;
2012-01-01
In this paper, a FEM (finite element method) based mechanical model for PP (press-pack) IGBTs (insulated gate bipolar transistors) is presented, which can be used to calculate the clamping force distribution among chips under various clamping conditions. The clamping force is an important parameter...... for the chip, because it influences contact electrical resistance, contact thermal resistance and power cycling capability. Ideally, the clamping force should be equally distributed among chips, in order to maximize the reliability of the PP IGBT. The model is built around a hypothetical PP IGBT with 9 chips......, and it has numerous simplifications in order to reduce the simulation time as much as possible. The developed model is used to analyze the clamping force distribution among chips, in various study cases, where uniform and non-uniform clamping pressures are applied on the studied PP IGBT....
An Approximate Method for Calculation of Fluid Force and Response of A Circular Cylinder at Lock-in
Institute of Scientific and Technical Information of China (English)
WANG Yi
2008-01-01
In this paper, equations calculating lift force of a rigid circular cylinder at lock-in in uniform flow are deduced in detail. Besides, equations calculating the lift force on a long flexible circular cylinder at lock-in are deduced based on mode analysis of a multi-degree freedom system. The simplified forms of these equations are also given. Furthermore, an approximate method to predict the forces and response of rigid circular cylinders and long flexible circular cylinders at lock-in is introduced in the case of low mass-damping ratio. A method to eliminate one deficiency of these equations is introduced. Comparison with experimental results shows the effectiveness of this approximate method.
Energy Technology Data Exchange (ETDEWEB)
Shiohata, K.; Nemoto, K.; Nagawa, Y.; Sakamoto, S.; Kobayashi, T.; Ito, M.; Koharagi, H. [Hitachi, Ltd, Tokyo (Japan)
1998-11-01
In this analysis method, electromagnetic force calculated by 2-dimensional analysis is transformed into external force for 3-dimensional structural-vibration analysis. And a modeling procedure for a vibrating structure is developed. Further, a space-modal-resonance criteria which relates electromagnetic force to structural-vibration or noise is introduced. In the structural-vibration analysis, the finite element method is used; and in the noise analysis, the boundary element method is used. Finally, vibration and noise of an induction motor are calculated using this criteria. Consequently, high-accuracy modeling is achieved and noise the calculated by the simulation almost coincides with that obtained by experiments. And it is clarified that the-space-modal resonance criteria is effective in numerical simulation. 11 refs., 9 figs., 3 tabs.
Pope, Devin G.; Price, Joseph; Wolfers, Justin
2014-01-01
Can raising awareness of racial bias subsequently reduce that bias? We address this question by exploiting the widespread media attention highlighting racial bias among professional basketball referees that occurred in May 2007 following the release of an academic study. Using new data, we confirm that racial bias persisted in the years after the study's original sample, but prior to the media coverage. Subsequent to the media coverage though, the bias completely disappeared. We examine poten...
DEFF Research Database (Denmark)
Troldborg, Niels; Sørensen, Niels N.; Réthoré, Pierre-Elouan;
2015-01-01
This paper describes a consistent algorithm for eliminating the numerical wiggles appearing when solving the finite volume discretized Navier-Stokes equations with discrete body forces in a collocated grid arrangement. The proposed method is a modification of the Rhie-Chow algorithm where the force...... in a cell is spread on neighboring cells by applying equivalent pressure jumps at the cell faces. The method shows excellent results when applied for simulating the flow through an actuator disk, which is relevant for wind turbine wake simulations. (c) 2015 Elsevier Ltd. All rights reserved....
An Improved Calibration Method for Hydrazine Monitors for the United States Air Force
Energy Technology Data Exchange (ETDEWEB)
Korsah, K
2003-07-07
This report documents the results of Phase 1 of the ''Air Force Hydrazine Detector Characterization and Calibration Project''. A method for calibrating model MDA 7100 hydrazine detectors in the United States Air Force (AF) inventory has been developed. The calibration system consists of a Kintek 491 reference gas generation system, a humidifier/mixer system which combines the dry reference hydrazine gas with humidified diluent or carrier gas to generate the required humidified reference for calibrations, and a gas sampling interface. The Kintek reference gas generation system itself is periodically calibrated using an ORNL-constructed coulometric titration system to verify the hydrazine concentration of the sample atmosphere in the interface module. The Kintek reference gas is then used to calibrate the hydrazine monitors. Thus, coulometric titration is only used to periodically assess the performance of the Kintek reference gas generation system, and is not required for hydrazine monitor calibrations. One advantage of using coulometric titration for verifying the concentration of the reference gas is that it is a primary standard (if used for simple solutions), thereby guaranteeing, in principle, that measurements will be traceable to SI units (i.e., to the mole). The effect of humidity of the reference gas was characterized by using the results of concentrations determined by coulometric titration to develop a humidity correction graph for the Kintek 491 reference gas generation system. Using this calibration method, calibration uncertainty has been reduced by 50% compared to the current method used to calibrate hydrazine monitors in the Air Force inventory and calibration time has also been reduced by more than 20%. Significant findings from studies documented in this report are the following: (1) The Kintek 491 reference gas generation system (generator, humidifier and interface module) can be used to calibrate hydrazine detectors. (2) The
Institute of Scientific and Technical Information of China (English)
Jim Wang; Sheng-dun Zhao; Hu-shan Shi; Chun-jian Hua
2009-01-01
A new method to calculate and counterbalance the inertia force of slider-crank mechanisms in high-speed mechanical presses was put forward. By analyzing the kinematic characteristics of a center-located slider-crank mechanism whose crank rotates at a constant angular velocity, the kinematic parameters of the slide, connecting rod and crank were formulated approximately. On the basis of the results above, three inertia forces and the input moment in the mechanism during its idle running were investigated and formulated by dynamic analysis. A verification experiment was performed on a slider-crank mechanism at a high-speed press machine. The forces derived from the established formulas were compared respectively with those obtained by the ADAMS software and the classical method of connecting rod mass substitution. It was experimentally found that the proposed formulas have an improved performance over related earlier techniques. By use of these results, a 1000 kN 1250 rpm four-point high-speed press machine was designed and manufactured. The slide of this press is driven by four sets of slider-crank mechanisms with symmetrical layout and opposite rotation directions to counterbalance the horizontal inertia forces. Four eccentric counterbalance blocks were designed to counterbalance the vertical force after their mass and equivalent eccentric radius were formulated. The high-speed press machine designed by the proposed counterbalance method has worked with satisfactory performance and good dynamic balance for more than four years in practical production.
Tactics, methods and techniques to improve Special Forces in-service enlisted recruiting
Burrell, Robert M.
2002-01-01
This thesis identifies and analyzes recruiting strategies that exist outside of the military service that might be considered to increase the number of high-quality enlisted recruits for the United States Army Special Forces Command (USASFC). The thesis contains a review of the current Special Forces recruiting processes and describes how Special Operations Recruiting Command (SORC) recruits enlisted soldiers. It also analyzes goal congruency and cohesion between SORC, SWCS(A), and USASFC(A)....
Approximate Method of Calculating Forces on Rudder During Ship Sailing on a Shipping Route
Directory of Open Access Journals (Sweden)
K. Zelazny
2014-09-01
Full Text Available Service speed of a ship in real weather conditions is a basic design parameter. Forecasting of this speed at preliminary design stage is made difficult by the lack of simple but at the same accurate models of forces acting upon a ship sailing on a preset shipping route. The article presents a model for calculating forces and moment on plane rudder, useful for forecasting of ship service speed at preliminary stages of ship design.
磁力泵轴向力测试方法%Axial Force Test Methods for Magnetic Driving Pump
Institute of Scientific and Technical Information of China (English)
左占库
2015-01-01
This paper presents a test method of axial force. Special tooling is used to test axial force of the produced magnetic pump, and judge whether the pump should be accepted or adjusted according the test results. The test method can improve controllability of the magnetic shaft axial force, so the working life of magnetic pump is improved.%提出一种磁力泵轴向力的测试方法，通过专用工装，对已生产完成的成品磁力泵进行轴向力测试，并通过测试结果来判断是进行调整还是可以接受，提高了磁力泵轴向力的可控性，从而延长磁力泵运行寿命。
Tang, Bin
2008-01-01
A method has been developed for determining the transient response of a beam. The beam is divided into several continuous Timoshenko beam elements. The overall dynamic stiffness matrix is assembled in turn. Using Leung's equation, we derive the overall mass and stiffness matrices which are more suitable for response analysis than the overall dynamic stiffness matrix. The forced vibration of the beam is computed by the precise time integration method. Three illustrative beams are discussed to evaluate the performance of the current method. Solutions calculated by the finite element method and theoretical analysis are also enumerated for comparison. In these examples, we have found that the current method can solve the forced vibration of structures with a higher precision.
Roche, Laurent; Danieli, Coraline; Belot, Aurélien; Grosclaude, Pascale; Bouvier, Anne-Marie; Velten, Michel; Iwaz, Jean; Remontet, Laurent; Bossard, Nadine
2013-05-15
Net survival, the survival which might occur if cancer was the only cause of death, is a major epidemiological indicator required for international or temporal comparisons. Recent findings have shown that all classical methods used for routine estimation of net survival from cancer-registry data, sometimes called "relative-survival methods," provide biased estimates. Meanwhile, an unbiased estimator, the Pohar-Perme estimator (PPE), was recently proposed. Using real data, we investigated the magnitude of the errors made by four "relative-survival" methods (Ederer I, Hakulinen, Ederer II and a univariable regression model) vs. PPE as reference and examined the influence of time of follow-up, cancer prognosis, and age on the errors made. The data concerned seven cancer sites (2,51,316 cases) collected by FRANCIM cancer registries. Net survivals were estimated at 5, 10 and 15 years postdiagnosis. At 5 years, the errors were generally small. At 10 years, in good-prognosis cancers, the errors made in nonstandardized estimates with all classical methods were generally great (+2.7 to +9% points in prostate cancer) and increased in age-class estimations (vs. 5-year ones). At 15 years, in bad- or average-prognosis cancers, the errors were often substantial whatever the nature of the estimation. In good-prognosis cancers, the errors in nonstandardized estimates of all classical methods were great and sometimes very important. With all classical methods, great errors occurred in age-class estimates resulting in errors in age-standardized estimates (+0.4 to +3.2% points in breast cancer). In estimating net survival, cancer registries should abandon all classical methods and adopt the new Pohar-Perme estimator. PMID:22961565
Rolling Force and Rolling Moment in Spline Cold Rolling Using Slip-line Field Method
Institute of Scientific and Technical Information of China (English)
ZHANG Dawei; LI Yongtang; FU Jianhua; ZHENG Quangang
2009-01-01
Rolling force and rolling moment are prime process parameter of external spline cold rolling. However, the precise theoretical formulae of rolling force and rolling moment are still very fewer, and the determination of them depends on experience. In the present study, the mathematical models of rolling force and rolling moment are established based on stress field theory of slip-line. And the isotropic hardening is used to improve the yield criterion. Based on MATLAB program language environment, calculation program is developed according to mathematical models established. The rolling force and rolling moment could be predicted quickly via the calculation program, and then the reliability of the models is validated by FEM. Within the range of module of spline m=0.5-1.5 mm, pressure angle of reference circle α=30.0°-45.0°, and number of spline teeth Z=19-54, the rolling force and rolling moment in rolling process (finishing rolling is excluded) are researched by means of virtualizing orthogonal experiment design. The results of the present study indicate that:the influences of module and number of spline teeth on the maximum rolling force and rolling moment in the process are remarkable;in the case of pressure angle of reference circle is little, module of spline is great, and number of spline teeth is little, the peak value of rolling force in rolling process may appear in the midst of the process;the peak value of rolling moment in rolling process appears in the midst of the process, and then oscillator weaken to a stable value. The results of the present study may provide guidelines for the determination of power of the motor and the design of hydraulic system of special machine, and provide basis for the farther researches on the precise forming process of external spline cold rolling.
Degtiarenko, Pavel V.; Popov, Vladimir E.
2011-03-22
A first stage electronic system for receiving charge or current from voltage-controlled sensors or detectors that includes a low input impedance current receiver/converter device (for example, a transimpedance amplifier), which is directly coupled to the sensor output, a source of bias voltage, and the device's power supply (or supplies), which use the biased voltage point as a baseline.
Energy Technology Data Exchange (ETDEWEB)
Lu Yiyun, E-mail: luyiyun6666@vip.sohu.co [Luoyang Institute of Science and Technology, Luoyang, Henan 471023 (China); Qin Yujie; Dang Qiaohong [Luoyang Institute of Science and Technology, Luoyang, Henan 471023 (China); Wang Jiasu [Applied Superconductivity Laboratory, Southwest Jiaotong University, P.O. Box 152, Chengdu, Sichuan 610031 (China)
2010-12-01
The crossing in magnetic levitation force-gap hysteresis curve of melt high-temperature superconductor (HTS) vs. NdFeB permanent magnet (PM) was experimentally studied. One HTS bulk and PM was used in the experiments. Four experimental methods were employed combining of high/low speed of movement of PM with/without heat insulation materials (HIM) enclosed respectively. Experimental results show that crossing of the levitation force-gap curve is related to experimental methods. A crossing occurs in the magnetic force-gap curve while the PM moves approaching to and departing from the sample with high or low speed of movement without HIM enclosed. When the PM is enclosed with HIM during the measurement procedures, there is no crossing in the force-gap curve no matter high speed or low speed of movement of the PM. It was found experimentally that, with the increase of the moving speed of the PM, the maximum magnitude of levitation force of the HTS increases also. The results are interpreted based on Maxwell theories and flux flow-creep models of HTS.
Institute of Scientific and Technical Information of China (English)
WU Jian; LIU Hong-nian; WANG Wei-guo; LIU Gang
2006-01-01
@@ 1 INTRODUCTION Of three main methods for studying the radiative forcing of anthropogenic sulfate and climatic response on the regional scale, the first is, with given rates for transforming SO2 to sulfate, converting actually released SO2 into sulfate and acquiring the distribution of sulfate by computing transfer equations in the climate model.
Hritz, A. D.; Raymond, T. M.; Dutcher, D. D.
2016-01-01
Accurate estimates of particle surface tension are required for models concerning atmospheric aerosol nucleation and activation. However, it is difficult to collect sufficiently large volumes of atmospheric aerosol for use in typical instruments that measure surface tension, such as goniometers or Wilhelmy plates. In this work, a method that measures the surface tension of collected liquid nanoparticles using atomic force microscopy is presented. A...
DEFF Research Database (Denmark)
Lynov, Jens-Peter; Bergeron, K.; Coutsias, E.A.;
2000-01-01
We present an efficient spectral method for studies of fundamental vortex dynamics in forced, circular shear flows. The numerical results are compared with results from experiments carried out in rotating flows with both planar and parabolic geometries, Due to the high accuracy of the code, it can...
Janssens, M.H.A.; Verheij, J.W.; Loyau, T.
2002-01-01
In the analysis of machinery noise the aspect of sound source characterisation is of importance. Unlike for airborne sources, no widely applicable methods are available yet for structure-borne sound sources. In previous work a 'pseudo-forces' methodology was suggested. In this approach fictitious fo
Baran, Oleh; Ertas, Deniz; Halsey, Thomas; Zhou, Fuping
2007-03-01
Using three-dimensional molecular dynamics simulations, we study steady gravity-driven flows of frictional inelastic spheres of diameter d and density ρg down an incline, interacting through two-body lubrication forces in addition to granular contact forces. Scaling arguments suggest that, in 3D, these forces constitute the dominant perturbation of an interstitial fluid for small Reynolds number Re and low fluid densityρ. Two important parameters that characterize the strength of the lubrication forces are fluid viscosity and grain roughness. We observe that incline flows with lubrication forces exhibit a packing density that decreases with increasing distance from the surface. As the incline angle is increased, this results in a severely dilated basal layer that looks like ``hydroplaning'' similar to that observed in geological subaqueous debris flows. This is surprising since the model explicitly disallows any buildup of fluid pressure in the base of the flow, and suggests that hydroplaning might have other contributing factors besides this traditional explanation. The local packing density is still determined by the dimensionless strain rate I≡γ1ptd√ρg/p , where p is the average normal stress, obeying a ``dilatancy law'' similar to dry granular flows.
A Deployment Method Based on Spring Force in Wireless Robot Sensor Networks
Directory of Open Access Journals (Sweden)
Xiangyu Yu
2014-05-01
Full Text Available Robotic sensor deployment is fundamental for the effectiveness of wireless robot sensor networks - a good deployment algorithm leads to good coverage and connectivity with low energy consumption for the whole network. Virtual force-based algorithms (VFAs is one of the most popular approaches to this problem. In VFA, sensors are treated as points subject to repulsive and attractive forces exerted among them - sensors can move according to imaginary force generated in algorithms. In this paper, a virtual spring force-based algorithm with proper damping is proposed for the deployment of sensor nodes in a wireless sensor network (WSN. A new metric called Pair Correlation Diversion (PCD is introduced to evaluate the uniformity of the sensor distribution. Numerical simulations showed that damping can affect the network coverage, energy consumption, convergence time and general topology in the deployment. Moreover, it was found that damping effect (imaginary friction force has significant influence on algortithm outcomes. In addition, when working under approximate critical-damping condition, the proposed approach has the advantage of a higher coverage rate, better configurational uniformity and less energy consumption.
Institute of Scientific and Technical Information of China (English)
杨芃焘; 杨万民; 王妙; 李佳伟; 郭玉霞
2015-01-01
The influence of the width of the middle magnet in the permanent magnet guideways (PMGs) on the levitation force and the levitation height of single-domain yttrium barium copper oxide (YBCO) bulks has been investigated at 77 K under the zero field cooled (ZFC) state. It is found that the largest levitation force can be obtained in the system with the width of the middle magnet of the PMG equal to the size of the YBCO bulk when the gap between the YBCO bulk and PMG is small. Both larger levitation force and higher levitation height can be obtained in the system with the width of the middle magnet of the PMG larger than the size of the YBCO bulk. The stiffness of the levitation force between the PMG and the YBCO bulk is higher in the system with a smaller width of the middle magnet in the PMG. These results provide an effective way to control the levitation force and the levitation height for the superconducting maglev design and applications.
Challenges in bias correcting climate change simulations
Maraun, Douglas; Shepherd, Ted; Zappa, Giuseppe; Gutierrez, Jose; Widmann, Martin; Hagemann, Stefan; Richter, Ingo; Soares, Pedro; Mearns, Linda
2016-04-01
Biases in climate model simulations - if these are directly used as input for impact models - will introduce further biases in subsequent impact simulations. In response to this issue, so-called bias correction methods have been developed to post-process climate model output. These methods are now widely used and a crucial component in the generation of high resolution climate change projections. Bias correction is conceptually similar to model output statistics, which has been successfully used for several decades in numerical weather prediction. Yet in climate science, some authors outrightly dismiss any form of bias correction. Starting from this seeming contradiction, we highlight differences between the two contexts and infer consequences and limitations for the applicability of bias correction to climate change projections. We first show that cross validation approaches successfully used to evaluate weather forecasts are fundamentally insufficient to evaluate climate change bias correction. We further demonstrate that different types of model mismatches with observations require different solutions, and some may not sensibly be mitigated. In particular we consider the influence of large-scale circulation biases, biases in the persistence of weather regimes, and regional biases caused by an insufficient representation of the flow-topography interaction. We conclude with a list of recommendations and suggestions for future research to reduce, to post-process, and to cope with climate model biases.
Pork tenderness estimation by taste panel, Warner-Bratzler shear force and on-line methods.
Van Oeckel, M J; Warnants, N; Boucqué, C V
1999-12-01
The extent to which modification of Warner-Bratzler shear force (WBSF) determinations, relating to storage and preparation of the meat, aperture of the V-shaped cutting blade and shearing velocity, improve the relationship with sensory tenderness perception of pork was studied. Additionally four on-line methods: pH1, FOP1 (light scattering), PQM1 (conductivity) and DDLT (Double Density Light Transmission), were evaluated for their ability to predict tenderness. Sensory tenderness evaluation was conducted on 120 frozen (at -18°C for several months) samples of m. longissimus thoracis et lumborum. After overnight thawing, the meat was grilled to an internal temperature of 74°C and scored on an eight-point scale, from extremely tough to extremely tender. The standard WBSF procedure (protocol A) consisted of heating fresh meat samples (stored for 48 h at 4°C post slaughter) at 75°C for 50 min, cooling in cold tap water for 40 min, taking cylindrical cores parallel to the fibre direction, and shearing at a velocity of 200 mm/min with a blade aperture of 60°. For the prediction of sensory tenderness, the WBSF standard procedure (protocol A) showed the lowest variance (R(2)=15%) and the highest standard error of the estimate (SEE=0.97 N) compared to the other WBSF protocols. A decrease in shearing velocity, from 200 to 100 mm/min and, a replacement of the cutting blade with an aperture of 60° by one with an aperture of 30° led to improvements of R(2) (respectively, 19% vs. 13% and 47% vs. 23%) and SEE (respectively, 0.93 N vs. 0.97 N and 0.80 N vs. 0.97 N) and thus were better predictors of tenderness. A blade aperture of 30° instead of 60° also led to considerably lower WBSF values (22.1 N vs. 30.0 N). Freezing, frozen storage and thawing of the meat, prior to WBSF measurement, resulted in higher shear force values (32.7 N vs. 28.7 N) and a better prediction of tenderness, R(2) (25% vs. 15%) and SEE (0.94 N vs. 1.00 N). Furthermore, preparing the frozen stored
Pork tenderness estimation by taste panel, Warner-Bratzler shear force and on-line methods.
Van Oeckel, M J; Warnants, N; Boucqué, C V
1999-12-01
The extent to which modification of Warner-Bratzler shear force (WBSF) determinations, relating to storage and preparation of the meat, aperture of the V-shaped cutting blade and shearing velocity, improve the relationship with sensory tenderness perception of pork was studied. Additionally four on-line methods: pH1, FOP1 (light scattering), PQM1 (conductivity) and DDLT (Double Density Light Transmission), were evaluated for their ability to predict tenderness. Sensory tenderness evaluation was conducted on 120 frozen (at -18°C for several months) samples of m. longissimus thoracis et lumborum. After overnight thawing, the meat was grilled to an internal temperature of 74°C and scored on an eight-point scale, from extremely tough to extremely tender. The standard WBSF procedure (protocol A) consisted of heating fresh meat samples (stored for 48 h at 4°C post slaughter) at 75°C for 50 min, cooling in cold tap water for 40 min, taking cylindrical cores parallel to the fibre direction, and shearing at a velocity of 200 mm/min with a blade aperture of 60°. For the prediction of sensory tenderness, the WBSF standard procedure (protocol A) showed the lowest variance (R(2)=15%) and the highest standard error of the estimate (SEE=0.97 N) compared to the other WBSF protocols. A decrease in shearing velocity, from 200 to 100 mm/min and, a replacement of the cutting blade with an aperture of 60° by one with an aperture of 30° led to improvements of R(2) (respectively, 19% vs. 13% and 47% vs. 23%) and SEE (respectively, 0.93 N vs. 0.97 N and 0.80 N vs. 0.97 N) and thus were better predictors of tenderness. A blade aperture of 30° instead of 60° also led to considerably lower WBSF values (22.1 N vs. 30.0 N). Freezing, frozen storage and thawing of the meat, prior to WBSF measurement, resulted in higher shear force values (32.7 N vs. 28.7 N) and a better prediction of tenderness, R(2) (25% vs. 15%) and SEE (0.94 N vs. 1.00 N). Furthermore, preparing the frozen stored
An extended force density method for form finding of constrained cable nets
Directory of Open Access Journals (Sweden)
Ghada Aboul-Nasr
2015-06-01
This paper studied the prestressed cable nets and the loaded cable nets. For prestressed cable nets, coordinate constraints to all nodes of the cable net are introduced to modify the shape after graphically examining the preliminary shape. This preliminary shape resulted from linear analysis of assumed distribution of cable force densities. For analyzing cable nets under different load cases, the first load case is analyzed to achieve the coordinate constraints assigned to nodes. Analysis results are node coordinates, cable forces and lengths. Young’s modulus and areas of cables are used to calculate the unstressed length of all cables using materialization equations, those lengths are used as constraint in the analysis of other load cases. Forces in all cables under different load cases/combinations are calculated. By using this approach, design of cable net under static load is simplified.
A method to transfer distributed Lorentz forces in 3D to a finite element mechanical model
Milanese, A
2011-01-01
The problem of transferring distributed Lorentz forces acting on a coil to a mechanical mesh in 3D is studied. The same analysis was presented a few months ago for the 2D case. Although the physics and the mathematical procedure is the same, the actual details are different enough to be worth being analyzed. With these routines it is possible to perform the magnetic analysis with one tool (for example, ROXIE in 2D, Vector Fields Opera in 3D) and then to project the Lorentz forces on an independent mechanical mesh (for example, in ANSYS). This has the potential to streamline the design of superconducting magnets; a similar analysis strategy is adopted at LBNL. An appendix lists an example of code that can be used to transfer such forces, in an attempt to provide a ready-to-use recipe to the interested engineer.
Calculation Method for Effect of Silt Sediment on Lifting Force of HydraulicGate
Institute of Scientific and Technical Information of China (English)
Gao Shizhao; Xu Guobin; Wang Mingbin
2015-01-01
In this paper, silt sediment is considered to be Bingham body, which is made up of coarse and fine parti-cles in front of a hydraulic gate. The coarse and fine particles provide friction and shear stress in the course of opening the gate. They constitute together the adhesion force of the sediment. Based on this viewpoint, this paper putsforward a formula for the effect of silt sediment on the lifting force. The formula includes gate weight, down-suction force, sealing rubber friction, plus-weight, water-column pressure, plus-silted-sediment weight and rolling(or sliding)-bearing friction. Finally, the verification results show that the formula has certain reliability and the calculation accu-racy can meet the need of practical engineering.
Image method in the calculation of the van der Waals force between an atom and a conducting surface
Souza, Reinaldo de Melo e; Sigaud, C; Farina, C
2012-01-01
Initially, we make a detailed historical survey of van der Waals forces, collecting the main references on the subject. Then, we review a method recently proposed by Eberlein and Zietal to compute the dispersion van der Waals interaction between a neutral but polarizable atom and a perfectly conducting surface of arbitrary shape. This method has the advantage of relating the quantum problem to a corresponding classical one in electrostatics so that all one needs is to compute an appropriate Green function. We show how the image method of electrostatics can be conveniently used together with the Eberlein and Zietal mehtod (when the problem admits an image solution). We then illustrate this method in a couple of simple but important cases, including the atom-sphere system. Particularly, in our last example, we present an original result, namely, the van der Waals force between an atom and a boss hat made of a grounded conducting material.
Institute of Scientific and Technical Information of China (English)
无
2009-01-01
A new method to calculate and counterbalance the inertia force of slider-crank mechanisms in high-speed mechanical presses was put forward. By analyzing the kinematic characteristics of a center-located slider-crank mechanism whose crank rotates at a constant angular velocity,the kinematic parameters of the slide,connecting rod and crank were formulated approximately. On the basis of the results above,three inertia forces and the input moment in the mechanism during its idle running were investigated and fo...
Institute of Scientific and Technical Information of China (English)
2008-01-01
Computational prediction of adsorption of small molecules in porous materials has great impact on the basic and applied research in chemical engineering and material sciences. In this work,we report an approach based on grand canonical ensemble Monte Carlo(GCMC) simulations and ab initio force fields. We calculated the adsorption curves of ammonia in ZSM-5 zeolite and hydrogen in MOF-5(a metal-organic-framework material). The predictions agree well with experimental data. Because the predictions are based on the first principle force fields,this approach can be used for the adsorption prediction of new molecules or materials without experimental data as guidance.
Energy Technology Data Exchange (ETDEWEB)
Crescimanno, P.J.; Keller, K.L.
1981-03-01
Analytical methods and test data employed in the core design of bolted joints for the LWBR core are presented. The effects of external working loads, thermal expansion, and material stress relaxation are considered in the formulation developed to analyze joint performance. Extensions of these methods are also provided for bolted joints having both axial and bending flexibilities, and for the effect of plastic deformation on internal forces developed in a bolted joint. Design applications are illustrated by examples.
International Nuclear Information System (INIS)
Analytical methods and test data employed in the core design of bolted joints for the LWBR core are presented. The effects of external working loads, thermal expansion, and material stress relaxation are considered in the formulation developed to analyze joint performance. Extensions of these methods are also provided for bolted joints having both axial and bending flexibilities, and for the effect of plastic deformation on internal forces developed in a bolted joint. Design applications are illustrated by examples
Institute of Scientific and Technical Information of China (English)
罗渝; 许强; 何思明; 李新坡; 何尽川; 吴永
2015-01-01
A new method based on the multi-wedge translation mechanism is presented to calculate the lateral force acting on the stabilizing piles. At first, there is no assumption for the shape of potential sliding surface, it is just considered that the potential sliding surface is a composite of a number of straight lines. And then, the potential sliding mass is divided into a number of triangular wedges take with these straight lines as its base. The kinematic theorem of limit analysis is adopted to calculate the rate of external work and the rate of energy dissipation for each triangular wedge, respectively. Furthermore, the multivariate functions are established to calculate the lateral force acting on the stabilizing piles. The lateral force and the corresponding potential sliding surfaces can be obtained by an optimizational technique. At last, an example is taken to illustrate the method. The effect of soil strength parameters, slope angle and pile roughness on the lateral force and the corresponding potential sliding surface are analyzed. The result are compared with those obtained using other methods.
Directory of Open Access Journals (Sweden)
Nickolas Vlahopoulos
1999-01-01
Full Text Available In this paper a new methodology is presented for applying measured accelerations and forces as excitation on a structural finite element model in order to perform a forced frequency response analysis. The computed vibration constitutes the excitation for an acoustic boundary element analysis. The new developments presented in this paper are associated with: the equivalent force method that can prescribe the acceleration at certain parts of the structure; the integration within a single process of test data that define the excitation, with the vibration analysis, and the acoustic prediction; the utilization of the new technology in simulating the noise radiated from a running engine and determining the effects of design changes. Numerical results for noise radiated from a running engine are compared to test data for a baseline design. The effect of two structural design modifications on the radiated noise is computed, and conclusions are deduced.
Method and system for measuring gate valve clearances and seating force
Casada, Donald A.; Haynes, Howard D.; Moyers, John C.; Stewart, Brian K.
1996-01-01
Valve clearances and seating force, as well as other valve operational parameters, are determined by measuring valve stem rotation during opening and closing operations of a translatable gate valve. The magnitude of the stem rotation, and the relative difference between the stem rotation on opening and closing provides valuable data on the valve internals in a non-intrusive manner.
STUDY OF MAGNETOSTRICTIVE PROPERTIES OF MATERIALS BY MEANS OF METHOD OF ATOMIC FORCE MICROSCOPY
Directory of Open Access Journals (Sweden)
D. A. Stepanenko
2014-01-01
Full Text Available The article studies and experimentally proves possibility of application of atomic force microscope for measurement of small magnetostrictive deformations of materials. Exemplary results of measurements for the samples made of technically pure nickel exhibiting strong magnetostrictive effect are presented.
利用场路结合方法分析磁轴承悬浮力%Levitation force analysis of magnetic bearing by circuit-field combination method
Institute of Scientific and Technical Information of China (English)
王大朋; 王凤翔
2011-01-01
针对磁轴承悬浮力分析比较复杂的问题,提出利用场路结合分析磁轴承悬浮力的方法.基于磁路法推导了径向磁轴承悬浮力的线性化模型,针对具体的磁轴承系统,利用有限元法分析了磁轴承能够满足线性化模型的偏置电流选择范围和磁轴承转子偏移范围,通过最小二乘法修正了线性化模型的电流刚度系数和位移刚度系数,并对超出线性化模型范围的悬浮力进行了分析,采用多项式拟合的方法推导了悬浮力的非线性模型.对所推导的磁轴承悬浮力模型进行了实验验证.分析及实验结果表明:由于磁饱和等因素的影响,利用磁路法推导的线性悬浮力模型已不能充分描述磁轴承悬浮力特性,通过场路结合方法推导的悬浮力模型能够更准确地计算磁轴承悬浮力.%For the analysis of magnetic force of magnetic bearings is complicated, a levitation force analysis of magnetic bearing based on field-circuit coupled method was used. Firstly, the linear expressions of magnetic levitation force was deduced based on the analysis of magnetic circuit, then the ranges of bias current and operating which can satisfy linear model were analyzed by means of the finite element analysis, through least square method the current rigidity coefficient and displacement rigidity coefficient were modified, and the nonlinear expressions of magnetic levitation force was deduced by polynomial approximation for exceeding linear model range, and finally the finite element method was verified by experiment. The analysis and experimental results show that due to the magnetic saturation and other factors, and the levitation force model which was deduced by using of the magnetic circuit method can not adequately describe the magnetic bearing levitation force characteristics, and the levitation force model which was deduced by field-circuit method can more accurately calculate magnetic bearing levitation force.
Modelling cognitive affective biases in major depressive disorder using rodents.
Hales, Claire A; Stuart, Sarah A; Anderson, Michael H; Robinson, Emma S J
2014-10-01
Major depressive disorder (MDD) affects more than 10% of the population, although our understanding of the underlying aetiology of the disease and how antidepressant drugs act to remediate symptoms is limited. Major obstacles include the lack of availability of good animal models that replicate aspects of the phenotype and tests to assay depression-like behaviour in non-human species. To date, research in rodents has been dominated by two types of assays designed to test for depression-like behaviour: behavioural despair tests, such as the forced swim test, and measures of anhedonia, such as the sucrose preference test. These tests have shown relatively good predictive validity in terms of antidepressant efficacy, but have limited translational validity. Recent developments in clinical research have revealed that cognitive affective biases (CABs) are a key feature of MDD. Through the development of neuropsychological tests to provide objective measures of CAB in humans, we have the opportunity to use 'reverse translation' to develop and evaluate whether similar methods are suitable for research into MDD using animals. The first example of this approach was reported in 2004 where rodents in a putative negative affective state were shown to exhibit pessimistic choices in a judgement bias task. Subsequent work in both judgement bias tests and a novel affective bias task suggest that these types of assay may provide translational methods for studying MDD using animals. This review considers recent work in this area and the pharmacological and translational validity of these new animal models of CABs. PMID:24467454
Directory of Open Access Journals (Sweden)
Gil eHerrnstadt
2015-03-01
Full Text Available Modern rehabilitation practices have begun integrating robots, recognizing their significant role in recovery. New and alternative stroke rehabilitation treatments are essential to enhance efficacy and mitigate associated health costs. Today’s robotic interventions can play a significant role in advancing rehabilitation. In addition, robots have an inherent ability to perform tasks accurately and reliably and are typically well suited to measure and quantify performance.Most rehabilitation strategies predominantly target activation of the paretic arm. However, bimanual upper limb rehabilitation research suggests potential in enhancing functional recovery. Moreover studies suggest limb coordination and synchronization can improve treatment efficacy.In this preliminary study, we aimed to investigate and validate our user-driven bimanual system in a reduced intensity rehab practice. A Bimanual Wearable Robotic Device (BWRD with a Master-Slave configuration for the elbow joint was developed to carry out the investigation. The BWRD incorporates position and force sensors for which respective control loops are implemented, and offers varying modes of operation ranging from passive to active training. The proposed system enables the perception of the movements, as well as the forces applied by the hemiparetic arm, with the non-hemiparetic arm. Eight participants with chronic unilateral stroke were recruited to participate in a total of three one-hour sessions per participant, delivered in a week. Participants underwent pre and post training functional assessments along with proprioceptive measures. The post assessment was performed at the end of the last training session.The protocol was designed to engage the user in an assortment of static and dynamic arm matching and opposing tasks. The training incorporates force feedback movements, force feedback positioning, and force matching tasks with same and opposite direction movements. We are able to
Yang, Peng-Tao; Yang, Wan-Min; Wang, Miao; Li, Jia-Wei; Guo, Yu-Xia
2015-11-01
The influence of the width of the middle magnet in the permanent magnet guideways (PMGs) on the levitation force and the levitation height of single-domain yttrium barium copper oxide (YBCO) bulks has been investigated at 77 K under the zero field cooled (ZFC) state. It is found that the largest levitation force can be obtained in the system with the width of the middle magnet of the PMG equal to the size of the YBCO bulk when the gap between the YBCO bulk and PMG is small. Both larger levitation force and higher levitation height can be obtained in the system with the width of the middle magnet of the PMG larger than the size of the YBCO bulk. The stiffness of the levitation force between the PMG and the YBCO bulk is higher in the system with a smaller width of the middle magnet in the PMG. These results provide an effective way to control the levitation force and the levitation height for the superconducting maglev design and applications. Project supported by the National Natural Science Foundation of China (Grant Nos. 51342001 and 50872079), the Key-grant Project of Chinese Ministry of Education (Grant No. 311033), the Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20120202110003), the Innovation Team in Shaanxi Province, China (Grant No. 2014KTC-18), and the Fundamental Research Funds for the Central Universities, China (Grant Nos. GK201101001 and GK201305014), and the Outstanding Doctoral Thesis Foundation Project of Shaanxi Normal University, China (Grant Nos. X2011YB08 and X2012YB05).
Herrnstadt, Gil; Alavi, Nezam; Randhawa, Bubblepreet Kaur; Boyd, Lara A; Menon, Carlo
2015-01-01
Modern rehabilitation practices have begun integrating robots, recognizing their significant role in recovery. New and alternative stroke rehabilitation treatments are essential to enhance efficacy and mitigate associated health costs. Today's robotic interventions can play a significant role in advancing rehabilitation. In addition, robots have an inherent ability to perform tasks accurately and reliably and are typically well suited to measure and quantify performance. Most rehabilitation strategies predominantly target activation of the paretic arm. However, bimanual upper-limb rehabilitation research suggests potential in enhancing functional recovery. Moreover, studies suggest that limb coordination and synchronization can improve treatment efficacy. In this preliminary study, we aimed to investigate and validate our user-driven bimanual system in a reduced intensity rehab practice. A bimanual wearable robotic device (BWRD) with a Master-Slave configuration for the elbow joint was developed to carry out the investigation. The BWRD incorporates position and force sensors for which respective control loops are implemented, and offers varying modes of operation ranging from passive to active training. The proposed system enables the perception of the movements, as well as the forces applied by the hemiparetic arm, with the non-hemiparetic arm. Eight participants with chronic unilateral stroke were recruited to participate in a total of three 1-h sessions per participant, delivered in a week. Participants underwent pre- and post-training functional assessments along with proprioceptive measures. The post-assessment was performed at the end of the last training session. The protocol was designed to engage the user in an assortment of static and dynamic arm matching and opposing tasks. The training incorporates force-feedback movements, force-feedback positioning, and force matching tasks with same and opposite direction movements. We are able to suggest
Sato, Fumiya; Asakawa, Hitoshi; Fukuma, Takeshi; Terada, Sumio
2016-08-01
Neurofilaments are intermediate filament proteins specific for neurons and characterized by formation of biochemically stable, obligate heteropolymers in vivo While purified or reassembled neurofilaments have been subjected to morphological analyses by electron microscopy and atomic force microscopy, there has been a need for direct imaging of cytoplasmic genuine intermediate filaments with minimal risk of artefactualization. In this study, we applied the modified 'cells on glass sandwich' method to exteriorize intracellular neurofilaments, reducing the risk of causing artefacts through sample preparation. SW13vim(-) cells were double transduced with neurofilament medium polypeptide (NF-M) and alpha-internexin (α-inx). Cultured cells were covered with a cationized coverslip after prestabilization with tannic acid to form a sandwich and then split into two. After confirming that neurofilaments could be deposited on ventral plasma membranes exposed via unroofing, we performed atomic force microscopy imaging semi-in situ in aqueous solution. The observed thin filaments, considered to retain native structures of the neurofilaments, exhibited an approximate periodicity of 50-60 nm along their length. Their structural property appeared to reflect the morphology formed by their constituents, i.e. NF-M and α-inx. The success of semi-in situ atomic force microscopy of exposed bona fide assembled neurofilaments through separating the sandwich suggests that it can be an effective and alternative method for investigating cytoplasmic intermediate filaments under physiological conditions by atomic force microscopy.
Anhysteretic and biased first magnetization curves for Finemet-type toroidal samples
Varga, L. K.; Kovács, Gy.; Takács, J.
The anhysteretic and a set of biased first magnetization (BFMC) curves together with a set of first-order reversal curves (FORC) were measured and modeled by the hyperbolic T( x) model for a Finemet-type nanocrystalline toroidal sample with a round hysteresis loop. Similar to the FORC diagram, a "fingerprint"-like distribution has been obtained from a set of BFMC curves using the mixed second-derivate method of Pike. It is concluded that while the FORC diagram gives the distribution of coercive fields (or Preisach distribution), the BFMC diagram gives the distribution of the critical field where the domain wall magnetization become unstable and split up.
A Single-Vector Force Calibration Method Featuring the Modern Design of Experiments
Parker, P. A.; Morton, M.; Draper, N.; Line, W.
2001-01-01
This paper proposes a new concept in force balance calibration. An overview of the state-of-the-art in force balance calibration is provided with emphasis on both the load application system and the experimental design philosophy. Limitations of current systems are detailed in the areas of data quality and productivity. A unique calibration loading system integrated with formal experimental design techniques has been developed and designated as the Single-Vector Balance Calibration System (SVS). This new concept addresses the limitations of current systems. The development of a quadratic and cubic calibration design is presented. Results from experimental testing are compared and contrasted with conventional calibration systems. Analyses of data are provided that demonstrate the feasibility of this concept and provide new insights into balance calibration.
MEASUREMENTS OF SHOCK WAVE FORCE IN SHOCK TUBE WITH INDIRECT METHODS
Directory of Open Access Journals (Sweden)
Mario Dobrilović
2005-12-01
Full Text Available Tests have been conducted at the “Laboratory for testing of civil explosives, detonators, electrical detonators and pyrotechnical materials”, Department for mining and geotechnics of the Faculty of mining, geology and petroleum engineering, University of Zagreb with the purpose of designing a detonator that would unite advantages of a non-electric system and the precision in regulation of time delay in electronic initiation system. Sum of energy released by the wave force in shock tube is a pre-condition for operation of the new detonator, and measurement of wave force is the first step in determining the sum of energy. The sum of energy is measured indirectly, based on two principles: movement sensors and strain.
Method and apparatus for adaptive force and position control of manipulators
Seraji, Homayoun (Inventor)
1995-01-01
The described and improved multi-arm invention of this application presents three strategies for adaptive control of cooperative multi-arm robots which coordinate control over a common load. In the position-position control strategy, the adaptive controllers ensure that the end-effector positions of both arms track desired trajectories in Cartesian space despite unknown time-varying interaction forces exerted through a load. In the position-hybrid control strategy, the adaptive controller of one arm controls end-effector motions in the free directions and applied forces in the constraint directions; while the adaptive controller of the other arm ensures that the end-effector tracks desired position trajectories. In the hybrid-hybrid control strategy, the adaptive controllers ensure that both end-effectors track reference position trajectories while simultaneously applying desired forces on the load. In all three control strategies, the cross-coupling effects between the arms are treated as disturbances which are compensated for by the adaptive controllers while following desired commands in a common frame of reference. The adaptive controllers do not require the complex mathematical model of the arm dynamics or any knowledge of the arm dynamic parameters or the load parameters such as mass and stiffness. Circuits in the adaptive feedback and feedforward controllers are varied by novel adaptation laws.
Zhou, Y; Ojeda-May, P; Nagaraju, M; Pu, J
2016-01-01
Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are ubiquitous ATP-dependent membrane proteins involved in translocations of a wide variety of substrates across cellular membranes. To understand the chemomechanical coupling mechanism as well as functional asymmetry in these systems, a quantitative description of how ABC transporters hydrolyze ATP is needed. Complementary to experimental approaches, computer simulations based on combined quantum mechanical and molecular mechanical (QM/MM) potentials have provided new insights into the catalytic mechanism in ABC transporters. Quantitatively reliable determination of the free energy requirement for enzymatic ATP hydrolysis, however, requires substantial statistical sampling on QM/MM potential. A case study shows that brute force sampling of ab initio QM/MM (AI/MM) potential energy surfaces is computationally impractical for enzyme simulations of ABC transporters. On the other hand, existing semiempirical QM/MM (SE/MM) methods, although affordable for free energy sampling, are unreliable for studying ATP hydrolysis. To close this gap, a multiscale QM/MM approach named reaction path-force matching (RP-FM) has been developed. In RP-FM, specific reaction parameters for a selected SE method are optimized against AI reference data along reaction paths by employing the force matching technique. The feasibility of the method is demonstrated for a proton transfer reaction in the gas phase and in solution. The RP-FM method may offer a general tool for simulating complex enzyme systems such as ABC transporters. PMID:27498639
Zhou, Y.; Ojeda-May, P.; Nagaraju, M.; Pu, J.
2016-01-01
Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are ubiquitous ATP-dependent membrane proteins involved in translocations of a wide variety of substrates across cellular membranes. To understand the chemomechanical coupling mechanism as well as functional asymmetry in these systems, a quantitative description of how ABC transporters hydrolyze ATP is needed. Complementary to experimental approaches, computer simulations based on combined quantum mechanical and molecular mechanical (QM/MM) potentials have provided new insights into the catalytic mechanism in ABC transporters. Quantitatively reliable determination of the free energy requirement for enzymatic ATP hydrolysis, however, requires substantial statistical sampling on QM/MM potential. A case study shows that brute force sampling of ab initio QM/MM (AI/MM) potential energy surfaces is computationally impractical for enzyme simulations of ABC transporters. On the other hand, existing semiempirical QM/MM (SE/MM) methods, although affordable for free energy sampling, are unreliable for studying ATP hydrolysis. To close this gap, a multiscale QM/MM approach named reaction path–force matching (RP–FM) has been developed. In RP–FM, specific reaction parameters for a selected SE method are optimized against AI reference data along reaction paths by employing the force matching technique. The feasibility of the method is demonstrated for a proton transfer reaction in the gas phase and in solution. The RP–FM method may offer a general tool for simulating complex enzyme systems such as ABC transporters. PMID:27498639
Directory of Open Access Journals (Sweden)
Kováč Michal
2015-03-01
Full Text Available Thin-walled centrically compressed members with non-symmetrical or mono-symmetrical cross-sections can buckle in a torsional-flexural buckling mode. Vlasov developed a system of governing differential equations of the stability of such member cases. Solving these coupled equations in an analytic way is only possible in simple cases. Therefore, Goľdenvejzer introduced an approximate method for the solution of this system to calculate the critical axial force of torsional-flexural buckling. Moreover, this can also be used in cases of members with various boundary conditions in bending and torsion. This approximate method for the calculation of critical force has been adopted into norms. Nowadays, we can also solve governing differential equations by numerical methods, such as the finite element method (FEM. Therefore, in this paper, the results of the approximate method and the FEM were compared to each other, while considering the FEM as a reference method. This comparison shows any discrepancies of the approximate method. Attention was also paid to when and why discrepancies occur. The approximate method can be used in practice by considering some simplifications, which ensure safe results.
Energy Technology Data Exchange (ETDEWEB)
Valdes Hernandez, Maria del C.; Gonzalez-Castro, Victor; Wang, Xin; Doubal, Fergus; Munoz Maniega, Susana; Wardlaw, Joanna M. [Centre for Clinical Brian Sciences, Department of Neuroimaging Sciences, Edinburgh (United Kingdom); Ghandour, Dina T. [University of Edinburgh, College of Medicine and Veterinary Medicine, Edinburgh (United Kingdom); Armitage, Paul A. [University of Sheffield, Department of Cardiovascular Sciences, Sheffield (United Kingdom)
2016-05-15
Subtle inhomogeneities in the scanner's magnetic fields (B{sub 0} and B{sub 1}) alter the intensity levels of the structural magnetic resonance imaging (MRI) affecting the volumetric assessment of WMH changes. Here, we investigate the influence that (1) correcting the images for the B{sub 1} inhomogeneities (i.e. bias field correction (BFC)) and (2) selection of the WMH change assessment method can have on longitudinal analyses of WMH progression and discuss possible solutions. We used brain structural MRI from 46 mild stroke patients scanned at stroke onset and 3 years later. We tested three BFC approaches: FSL-FAST, N4 and exponentially entropy-driven homomorphic unsharp masking (E{sup 2}D-HUM) and analysed their effect on the measured WMH change. Separately, we tested two methods to assess WMH changes: measuring WMH volumes independently at both time points semi-automatically (MCMxxxVI) and subtracting intensity-normalised FLAIR images at both time points following image gamma correction. We then combined the BFC with the computational method that performed best across the whole sample to assess WMH changes. Analysis of the difference in the variance-to-mean intensity ratio in normal tissue between BFC and uncorrected images and visual inspection showed that all BFC methods altered the WMH appearance and distribution, but FSL-FAST in general performed more consistently across the sample and MRI modalities. The WMH volume change over 3 years obtained with MCMxxxVI with vs. without FSL-FAST BFC did not significantly differ (medians(IQR)(with BFC) = 3.2(6.3) vs. 2.9(7.4)ml (without BFC), p = 0.5), but both differed significantly from the WMH volume change obtained from subtracting post-processed FLAIR images (without BFC)(7.6(8.2)ml, p < 0.001). This latter method considerably inflated the WMH volume change as subtle WMH at baseline that became more intense at follow-up were counted as increase in the volumetric change. Measurement of WMH volume change remains
International Nuclear Information System (INIS)
Subtle inhomogeneities in the scanner's magnetic fields (B0 and B1) alter the intensity levels of the structural magnetic resonance imaging (MRI) affecting the volumetric assessment of WMH changes. Here, we investigate the influence that (1) correcting the images for the B1 inhomogeneities (i.e. bias field correction (BFC)) and (2) selection of the WMH change assessment method can have on longitudinal analyses of WMH progression and discuss possible solutions. We used brain structural MRI from 46 mild stroke patients scanned at stroke onset and 3 years later. We tested three BFC approaches: FSL-FAST, N4 and exponentially entropy-driven homomorphic unsharp masking (E2D-HUM) and analysed their effect on the measured WMH change. Separately, we tested two methods to assess WMH changes: measuring WMH volumes independently at both time points semi-automatically (MCMxxxVI) and subtracting intensity-normalised FLAIR images at both time points following image gamma correction. We then combined the BFC with the computational method that performed best across the whole sample to assess WMH changes. Analysis of the difference in the variance-to-mean intensity ratio in normal tissue between BFC and uncorrected images and visual inspection showed that all BFC methods altered the WMH appearance and distribution, but FSL-FAST in general performed more consistently across the sample and MRI modalities. The WMH volume change over 3 years obtained with MCMxxxVI with vs. without FSL-FAST BFC did not significantly differ (medians(IQR)(with BFC) = 3.2(6.3) vs. 2.9(7.4)ml (without BFC), p = 0.5), but both differed significantly from the WMH volume change obtained from subtracting post-processed FLAIR images (without BFC)(7.6(8.2)ml, p < 0.001). This latter method considerably inflated the WMH volume change as subtle WMH at baseline that became more intense at follow-up were counted as increase in the volumetric change. Measurement of WMH volume change remains challenging. Although
Institute of Scientific and Technical Information of China (English)
周子康; 崔斌
2003-01-01
Based on the adjustment of public financial revenue and expenditure of China according to the international comparable scope, the authors project and research the condition of public financial revenue and expenditure in China by using bias least square method. After the analysis, the authors think that the real public financial capability of China is not as weak as people estimate in advance.
Systematic study of even-even nuclei with Hartree-Fock+BCS method using Skyrme SIII force
Energy Technology Data Exchange (ETDEWEB)
Tajima, Naoki; Takahara, Satoshi; Onishi, Naoki [Tokyo Univ. (Japan). Coll. of Arts and Sciences
1997-03-01
We have applied the Hartree-Fock+BCS method with Skyrme SIII force formulated in a three-dimensional Cartesian-mesh representation to even-even nuclei with 2 {<=} Z {<=} 114. We discuss the results concerning the atomic masses, the quadrupole (m=0, 2) and hexadecapole (m=0, 2, 4) deformations, the skin thicknesses, and the halo radii. We also discuss the energy difference between oblate and prolate solutions and the shape difference between protons and neutrons. (author)
Inami, Eiichi; Sugimoto, Yoshiaki
2016-08-01
We propose a new method of extracting electrostatic force. The technique is based on frequency modulation atomic force microscopy (FM-AFM) combined with a voltage pulse. In this method, the work that the electrostatic field does on the oscillating tip is measured through the cantilever energy dissipation. This allows us to directly extract capacitive forces including the longer range part, to which the conventional FM-AFM is insensitive. The distance-dependent contact potential difference, which is modulated by local charges distributed on the surfaces of the tip and/or sample, could also be correctly obtained. In the absence of local charges, our method can perfectly reproduce the electrostatic force as a function of the distance and the bias voltage. Furthermore, we demonstrate that the system serves as a sensitive sensor enabling us to check the existence of the local charges such as trapped charges and patch charges.
Rival, D.; Schoenweitz, D.; Tropea, C.
2009-11-01
It is often very challenging or even impossible to measure the forces directly on swimming or flying animals. For this reason traditional control-volume methods are used to estimate the unsteady forces on the body in question. TR-PIV systems allow for the measurement of the full spatial and temporal velocity field in the control volume as well as along the bounding control surfaces. The corresponding pressure field can be integrated from the complete velocity-field data set. However, the measurement of the velocity field in the proximity of the body’s surface is at times cumbersome due to shadows and reflections. An alternate control-volume formulationfootnotetextJ. Z. Wu, Z.-L. Pan and X.-Y. Lu, ``Unsteady fluid-dynamic force solely in terms of control-surface integral,” Phys. of Fluids 17, 098102 (2005) eliminates the need for velocity measurements in the proximity of the body. This method has been tested and compared to the traditional control-volume technique for a generic pitching and plunging flat plate in a hover chamber. The advantages and disadvantages of these methods are discussed in the context of their measurement accuracy.
Measurement of intrinsic properties of amyloid fibrils by the peak force QNM method
Adamcik, Jozef; Lara, Cecile; Usov, Ivan; Jeong, Jae Sun; Ruggeri, Francesco S.; Dietler, Giovanni; Lashuel, Hilal A.; Hamley, Ian W.; Mezzenga, Raffaele
2012-07-01
We report the investigation of the mechanical properties of different types of amyloid fibrils by the peak force quantitative nanomechanical (PF-QNM) technique. We demonstrate that this technique correctly measures the Young's modulus independent of the polymorphic state and the cross-sectional structural details of the fibrils, and we show that values for amyloid fibrils assembled from heptapeptides, α-synuclein, Aβ(1-42), insulin, β-lactoglobulin, lysozyme, ovalbumin, Tau protein and bovine serum albumin all fall in the range of 2-4 GPa.
A Non-smooth Nonlinear Conjugate Gradient Method for Interactive Contact Force Problems
DEFF Research Database (Denmark)
Silcowitz, Morten; Niebe, Sarah Maria; Erleben, Kenny
2010-01-01
of a nonlinear complementarity problem (NCP), which can be solved using an iterative splitting method, such as the projected Gauss–Seidel (PGS) method. We present a novel method for solving the NCP problem by applying a Fletcher–Reeves type nonlinear nonsmooth conjugate gradient (NNCG) type method. We analyze...
Jonker, J.B.; Essen, van, A.M.
1997-01-01
A finite element based method has been developed for computing time-averaged fluid-induced radial excitation forces and rotor dynamic forces on a two-dimensional centrifugal impeller rotating and whirling in a volute casing. In this method potential flow theory is used, which implies the assumption of irrotational inviscid flow. In comparison with other analyses of fluid-induced impeller forces, two main features have been included. Firstly, the hydrodynamic interaction between impeller and v...
Bias Adjusted Precipitation Threat Scores
Directory of Open Access Journals (Sweden)
F. Mesinger
2008-04-01
Full Text Available Among the wide variety of performance measures available for the assessment of skill of deterministic precipitation forecasts, the equitable threat score (ETS might well be the one used most frequently. It is typically used in conjunction with the bias score. However, apart from its mathematical definition the meaning of the ETS is not clear. It has been pointed out (Mason, 1989; Hamill, 1999 that forecasts with a larger bias tend to have a higher ETS. Even so, the present author has not seen this having been accounted for in any of numerous papers that in recent years have used the ETS along with bias "as a measure of forecast accuracy".
A method to adjust the threat score (TS or the ETS so as to arrive at their values that correspond to unit bias in order to show the model's or forecaster's accuracy in extit{placing} precipitation has been proposed earlier by the present author (Mesinger and Brill, the so-called dH/dF method. A serious deficiency however has since been noted with the dH/dF method in that the hypothetical function that it arrives at to interpolate or extrapolate the observed value of hits to unit bias can have values of hits greater than forecast when the forecast area tends to zero. Another method is proposed here based on the assumption that the increase in hits per unit increase in false alarms is proportional to the yet unhit area. This new method removes the deficiency of the dH/dF method. Examples of its performance for 12 months of forecasts by three NCEP operational models are given.
Continuous surface force based lattice Boltzmann equation method for simulating thermocapillary flow
Zheng, Lin; Zheng, Song; Zhai, Qinglan
2016-02-01
In this paper, we extend a lattice Boltzmann equation (LBE) with continuous surface force (CSF) to simulate thermocapillary flows. The model is designed on our previous CSF LBE for athermal two phase flow, in which the interfacial tension forces and the Marangoni stresses as the results of the interface interactions between different phases are described by a conception of CSF. In this model, the sharp interfaces between different phases are separated by a narrow transition layers, and the kinetics and morphology evolution of phase separation would be characterized by an order parameter via Cahn-Hilliard equation which is solved in the frame work of LBE. The scalar convection-diffusion equation for temperature field is resolved by thermal LBE. The models are validated by thermal two layered Poiseuille flow, and two superimposed planar fluids at negligibly small Reynolds and Marangoni numbers for the thermocapillary driven convection, which have analytical solutions for the velocity and temperature. Then thermocapillary migration of two/three dimensional deformable droplet are simulated. Numerical results show that the predictions of present LBE agreed with the analytical solution/other numerical results.
Sertić, Josip; Kozak, Dražan; Samardžić, Ivan
2014-01-01
The values of reaction forces in the boiler supports are the basis for the dimensioning of bearing steel structure of steam boiler. In this paper, the application of the method of equivalent stiffness of membrane wall is proposed for the calculation of reaction forces. The method of equalizing displacement, as the method of homogenization of membrane wall stiffness, was applied. On the example of "Milano" boiler, using the finite element method, the calculation of reactions in the supports for the real geometry discretized by the shell finite element was made. The second calculation was performed with the assumption of ideal stiffness of membrane walls and the third using the method of equivalent stiffness of membrane wall. In the third case, the membrane walls are approximated by the equivalent orthotropic plate. The approximation of membrane wall stiffness is achieved using the elasticity matrix of equivalent orthotropic plate at the level of finite element. The obtained results were compared, and the advantages of using the method of equivalent stiffness of membrane wall for the calculation of reactions in the boiler supports were emphasized.
Comparison between Mean Forces and Swarms-of-Trajectories String Methods.
Maragliano, Luca; Roux, Benoît; Vanden-Eijnden, Eric
2014-02-11
The original formulation of the string method in collective variable space is compared with a recent variant called string method with swarms-of-trajectories. The assumptions made in the original method are revisited and the significance of the minimum free energy path (MFEP) is discussed in the context of reactive events. These assumptions are compared to those made in the string method with swarms-of-trajectories, and shown to be equivalent in a certain regime: in particular an expression for the path identified by the swarms-of-trajectories method is given and shown to be closely related to the MFEP. Finally, the algorithmic aspects of both methods are compared.
Germano, Fabrizio
2008-01-01
Within the spokes model of Chen and Riordan (2007) that allows for non-localized competition among arbitrary numbers of media outlets, we quantify the effect of concentration of ownership on quality and bias of media content. A main result shows that too few commercial outlets, or better, too few separate owners of commercial outlets can lead to substantial bias in equilibrium. Increasing the number of outlets (commercial and non-commercial) tends to bring down this bias; but the strong...
Detecting Gender Bias Through Test Item Analysis
González-Espada, Wilson J.
2009-03-01
Many physical science and physics instructors might not be trained in pedagogically appropriate test construction methods. This could lead to test items that do not measure what they are intended to measure. A subgroup of these items might show bias against some groups of students. This paper describes how the author became aware of potentially biased items against females in his examinations, which led to the exploration of fundamental issues related to item validity, gender bias, and differential item functioning, or DIF. A brief discussion of DIF in the context of university courses, as well as practical suggestions to detect possible gender-biased items, follows.
Directory of Open Access Journals (Sweden)
Eri Miura-Fujiwara
2009-12-01
Full Text Available One of the fabrication methods for functionally graded materials (FGMs is a centrifugal solid-particle method, which is an application of the centrifugal casting technique. However, it is the difficult to fabricate FGMs containing nano-particles by the centrifugal solid-particle method. Recently, we proposed a novel fabrication method, which we have named the centrifugal mixed-powder method, by which we can obtain FGMs containing nano-particles. Using this processing method, Cu-based FGMs containing SiC particles and Al-based FGMs containing TiO2 nano-particles on their surfaces have been fabricated. In this article, the microstructure and mechanical property of Cu/SiC and Al/TiO2 FGMs, fabricated by the centrifugal mixed-powder method are reviewed.
Jonker, J.B.; Essen, van T.G.
1997-01-01
A finite element based method has been developed for computing time-averaged fluid-induced radial excitation forces and rotor dynamic forces on a two-dimensional centrifugal impeller rotating and whirling in a volute casing. In this method potential flow theory is used, which implies the assumption
Ramos, A; Talaia, P; Queirós de Melo, F J
2016-01-01
The main goal of this work was to develop an approached model to study dynamic behavior and prediction of the stress distribution in an in vitro Charnley cemented hip arthroplasty. An alternative version of the described pseudo-dynamic procedure is proposed by using the time integration Newmark algorithm. An internal restoring force vector is numerically calculated from the displacement, velocity, and acceleration vectors. A numerical model of hip replacement was developed to analyze the deformation of a dynamically stressed structure for all time steps. The experimental measurement of resulting internal forces generated in the structure (internal restoring force vector) is the second fundamental step of the pseudo-dynamic procedure. These data (as a feedback) are used by the time integration algorithm, which allows updating of the structure's shape for the next displacement, velocity, and acceleration vectors. In the field of Biomechanics, the potentialities of this method contribute to the determination of a dynamically equivalent in vitro stress field of a cemented hip prosthesis; implant fitted in patients with a normal mobility or practice sports. Consequences of the stress distribution in the implant zone that underwent cyclic fatigue loads were also discussed by using a finite element model. Application of this method in Biomechanics appears as a useful tool in the approximate stress field characterization of the peak stress state. Results show a peak value around two times the static situation, more for making possible the prediction of future damage and a programed clinical examination in patients using hip prosthesis. PMID:25483822
Amano, Ken-ichi
2012-01-01
Recent surface force apparatus (SFA) and atomic force microscopy (AFM) can measure force curves between a probe and a sample surface in solvent. The force curve is thought as the solvation structure in some articles, because its shape is generally oscilltive and pitch of the oscillation is about the same as diameter of the solvent. However, it is not the solvation structure. It is only the force between the probe and the sample surface. Therefore, this brief paper presents a method for calculating the solvation structure from the force curve. The method is constructed by using integral equation theory, a statistical mechanics of liquid (Ornstein-Zernike equation coupled by hypernetted-chain closure). This method is considered to be important for elucidation of the solvation structure on a sample surface.
DEFF Research Database (Denmark)
Drecourt, J.-P.; Madsen, H.; Rosbjerg, Dan
2006-01-01
This paper reviews two different approaches that have been proposed to tackle the problems of model bias with the Kalman filter: the use of a colored noise model and the implementation of a separate bias filter. Both filters are implemented with and without feedback of the bias into the model state...... are illustrated on a simple one-dimensional groundwater problem. The results show that the presented filters outperform the standard Kalman filter and that the implementations with bias feedback work in more general conditions than the implementations without feedback. 2005 Elsevier Ltd. All rights reserved....
Interpretation biases in paranoia.
Savulich, George; Freeman, Daniel; Shergill, Sukhi; Yiend, Jenny
2015-01-01
Information in the environment is frequently ambiguous in meaning. Emotional ambiguity, such as the stare of a stranger, or the scream of a child, encompasses possible good or bad emotional consequences. Those with elevated vulnerability to affective disorders tend to interpret such material more negatively than those without, a phenomenon known as "negative interpretation bias." In this study we examined the relationship between vulnerability to psychosis, measured by trait paranoia, and interpretation bias. One set of material permitted broadly positive/negative (valenced) interpretations, while another allowed more or less paranoid interpretations, allowing us to also investigate the content specificity of interpretation biases associated with paranoia. Regression analyses (n=70) revealed that trait paranoia, trait anxiety, and cognitive inflexibility predicted paranoid interpretation bias, whereas trait anxiety and cognitive inflexibility predicted negative interpretation bias. In a group comparison those with high levels of trait paranoia were negatively biased in their interpretations of ambiguous information relative to those with low trait paranoia, and this effect was most pronounced for material directly related to paranoid concerns. Together these data suggest that a negative interpretation bias occurs in those with elevated vulnerability to paranoia, and that this bias may be strongest for material matching paranoid beliefs. We conclude that content-specific biases may be important in the cause and maintenance of paranoid symptoms.
Continuous surface force based lattice Boltzmann equation method for simulating thermocapillary flow
Zheng, Lin; Zhai, Qinglan
2014-01-01
In this paper, we extend a lattice Boltzmann equation (LBE) with continuous surface fore (CSF) to simulate thermocapillary flows. The model is designed on our previous CSF LBE for athermal two phase flow, in which the interfacial tension forces and the Marangoni stresses as the results of the interface interactions between different phases are described by a conception of CSF. In this model, the sharp interfaces between different phases are separated by a narrow transition layers, and the kinetics and morphology evolution of phase separation would be characterized by an order parameter visa Cahn-Hilliard equation which is solved in the frame work of LBE. The scalar convection-diffusion equation for temperature field is also solved by thermal LBE. The models are validated by thermal two layered Poiseuille flow, and a two superimposed planar fluids at negligibly small Reynolds and Marangoni numbers for the thermocapillary driven convection, which have analytical solutions for the velocity and temperature. Then ...
Yaghoubi, S.; Shirani, E.; Pishevar, A. R.; Afshar, Y.
2015-04-01
To simulate liquid fluid flows with high Schmidt numbers (Sc), one needs to use a modified version of the Dissipative Particle Dynamics (DPD) method. Recently the modifications made by others for the weight function of dissipative forces, enables DPD simulations for Sc, up to 10. In this paper, we introduce a different dissipative force weight function for DPD simulations that allows achieving a solution with higher values of Sc and improving the dynamic characteristics of the simulating fluid. Moreover, by reducing the energy of DPD particles, even higher values of Sc can be achieved. Finally, using the new proposed weight function and kBT =0.2 , the Sc values can reach up to 200.
Yuan, W.; Li, L.; Zhang, D. G.; Hong, J. Z.
2016-06-01
A flexible beam with large overall rotating motion impacting with a rigid slope is studied in this paper. The tangential friction force caused by the oblique impact is analyzed. The tangential motion of the system is divided into a stick state and a slip state. The contact constraint model and Coulomb friction model are used respectively to deal with the two states. Based on this hybrid modeling method, dynamic equations of the system, which include all states (before, during, and after the collision) are obtained. Simulation results of a concrete example are compared with the results obtained from two other models: a nontangential friction model and a modified Coulomb model. Differences in the results from the three models are discussed. The tangential friction force cannot be ignored when an oblique impact occurs. In addition, the results obtained from the model proposed in this paper are more consistent with real movement.
Lynch, J M; Barbano, D M; Healy, P A; Fleming, J R
1997-01-01
Results from collaborative studies of the performance of the direct forced-air oven-drying method for determination of milk total solids content (AOAC Method 990.20) and the Kjeldahl total nitrogen method for determination of milk total nitrogen content (AOAC Method 991.20) were published in 1989 and 1990, respectively. Method performance was characterized by using the harmonized ISO/IU-PAC/AOAC guidelines for method validation, and the methods now have final action status. During 1990 through 1995, the split sample collaborative study format was used to monitor the performance of these methods as part of a multilaboratory quality assurance program. Seven blind duplicate milk materials were sent from a central laboratory once every 2 months to participating laboratories. Data were analyzed with the same statistical procedures used in the original collaborative studies. Compared with the original collaborative study, the repeatability and reproducibility of the oven-drying method improved over time. For the Kjeldahl total nitrogen method, within-laboratory repeatability improved slightly, whereas between-laboratory reproducibility was similar to but not always as good as in the original study. The results demonstrate that the statistical protocol for collaborative studies can be used effectively as the basis for a multilaboratory quality assurance program and that the method performance achieved in a collaborative study can be maintained and even improved with time.
Stefanescu, Dan Mihai
2011-01-01
Part I introduces the basic ""Principles and Methods of Force Measurement"" acording to a classification into a dozen of force transducers types: resistive, inductive, capacitive, piezoelectric, electromagnetic, electrodynamic, magnetoelastic, galvanomagnetic (Hall-effect), vibrating wires, (micro)resonators, acoustic and gyroscopic. Two special chapters refer to force balance techniques and to combined methods in force measurement. Part II discusses the ""(Strain Gauge) Force Transducers Components"", evolving from the classical force transducer to the digital / intelligent one, with the inco
Bias-correction in vector autoregressive models
DEFF Research Database (Denmark)
Engsted, Tom; Pedersen, Thomas Quistgaard
2014-01-01
We analyze the properties of various methods for bias-correcting parameter estimates in both stationary and non-stationary vector autoregressive models. First, we show that two analytical bias formulas from the existing literature are in fact identical. Next, based on a detailed simulation study,...
Hritz, Andrew D.; Raymond, Timothy M.; Dutcher, Dabrina D.
2016-08-01
Accurate estimates of particle surface tension are required for models concerning atmospheric aerosol nucleation and activation. However, it is difficult to collect the volumes of atmospheric aerosol required by typical instruments that measure surface tension, such as goniometers or Wilhelmy plates. In this work, a method that measures, ex situ, the surface tension of collected liquid nanoparticles using atomic force microscopy is presented. A film of particles is collected via impaction and is probed using nanoneedle tips with the atomic force microscope. This micro-Wilhelmy method allows for direct measurements of the surface tension of small amounts of sample. This method was verified using liquids, whose surface tensions were known. Particles of ozone oxidized α-pinene, a well-characterized system, were then produced, collected, and analyzed using this method to demonstrate its applicability for liquid aerosol samples. It was determined that oxidized α-pinene particles formed in dry conditions have a surface tension similar to that of pure α-pinene, and oxidized α-pinene particles formed in more humid conditions have a surface tension that is significantly higher.
Bassenne, Maxime; Urzay, Javier; Park, George I.; Moin, Parviz
2016-03-01
This study investigates control-based forcing methods for incompressible homogeneous-isotropic turbulence forced linearly in physical space which result in constant turbulent kinetic energy, constant turbulent dissipation (also constant enstrophy), or a combination of the two based on a least-squares error minimization. The methods consist of proportional controllers embedded in the forcing coefficients. During the transient, the controllers adjust the forcing coefficients such that the controlled quantity achieves very early a minimal relative error with respect to its target stationary value. Comparisons of these forcing methods are made with the non-controlled approaches of Rosales and Meneveau ["Linear forcing in numerical simulations of isotropic turbulence: Physical space implementations and convergence properties," Phys. Fluids 17, 095106 (2005)] and Carroll and Blanquart ["A proposed modification to Lundgren's physical space velocity forcing method for isotropic turbulence," Phys. Fluids 25, 105114 (2013)], using direct numerical simulations (DNS) and large-eddy simulations (LES). The results indicate that the proposed constant-energetics forcing methods shorten the transient period from a user-defined artificial flow field to Navier-Stokes turbulence while maintaining steadier statistics. Additionally, the proposed method of constant kinetic-energy forcing behaves more robustly in coarse LES when initial conditions are employed that favor the occurrence of subgrid-scale backscatter, whereas the other approaches fail to provide physical turbulent flow fields. For illustration, the proposed forcing methods are applied to dilute particle-laden homogeneous-isotropic turbulent flows; the results serve to highlight the influences of the forcing strategies on the disperse-phase statistics.
Mack, A. H.; Schlingman, D. J.; Kamenetska, M.; Collins, R.; Regan, L.; Mochrie, S. G. J.
2013-08-01
By monitoring multiple molecular transitions, force-clamp, and trap-position-clamp methods have led to precise determinations of the free energies and free energy landscapes for molecular states populated in equilibrium at the same or similar forces. Here, we present a powerful new elaboration of the force-clamp and force-jump methods, applicable to transitions far from equilibrium. Specifically, we have implemented a live jump detection and force-clamp algorithm that intelligently adjusts and maintains the force on a single molecule in response to the measured state of that molecule. We are able to collect hundreds of individual molecular transitions at different forces, many times faster than previously, permitting us to accurately determine force-dependent lifetime distributions and reaction rates. Application of our method to unwinding and rewinding the nucleosome inner turn, using optical tweezers reveals experimental lifetime distributions that comprise a statistically meaningful number of transitions, and that are accurately single exponential. These measurements significantly reduce the error in the previously measured rates, and demonstrate the existence of a single, dominant free energy barrier at each force studied. A key benefit of the molecular yo-yo method for nucleosomes is that it reduces as far as possible the time spent in the tangentially bound state, which minimizes the loss of nucleosomes by dissociation.
Ditto, Peter H; Wojcik, Sean P; Chen, Eric Evan; Grady, Rebecca Hofstein; Ringel, Megan M
2015-01-01
Duarte et al. are right to worry about political bias in social psychology but they underestimate the ease of correcting it. Both liberals and conservatives show partisan bias that often worsens with cognitive sophistication. More non-liberals in social psychology is unlikely to speed our convergence upon the truth, although it may broaden the questions we ask and the data we collect.
Driving force analysis of the agricultural water footprint in China based on the LMDI method.
Zhao, Chunfu; Chen, Bin
2014-11-01
China's water scarcity problems have become more severe because of the unprecedented economic development and population explosion. Considering agriculture's large share of water consumption, obtaining a clear understanding of Chinese agricultural consumptive water use plays a key role in addressing China's water resource stress and providing appropriate water mitigation policies. We account for the Chinese agricultural water footprint from 1990 to 2009 based on bottom up approach. Then, the underlying driving forces are decomposed into diet structure effect, efficiency effect, economic activity effect, and population effect, and analyzed by applying a log-mean Divisia index (LMDI) model. The results reveal that the Chinese agricultural water footprint has risen from the 94.1 Gm3 in 1990 to 141 Gm3 in 2009. The economic activity effect is the largest positive contributor to promoting the water footprint growth, followed by the population effect and diet structure effect. Although water efficiency improvement as a significant negative effect has reduced overall water footprint, the water footprint decline from water efficiency improvement cannot compensate for the huge increase from the three positive driving factors. The combination of water efficiency improvement and dietary structure adjustment is the most effective approach for controlling the Chinese agricultural water footprint's further growth. PMID:25289879
Indian Academy of Sciences (India)
Izzet Karakurt
2014-10-01
In this paper, an optimization study was carried out for the cutting force (Fc) acting on circular diamond sawblades in rock sawing. The peripheral speed, traverse speed, cut depth and flow rate of cooling fluid were considered as operating variables and optimized by using Taguchi approach for the Fc. L16(44) orthogonal array was chosen for the experimental trials based on the operating variables and their levels. The signal-to-noise (S/N) ratios and the analysis of variance (ANOVA) were employed to determine optimum cutting conditions and significant operating variables, respectively. The Fc was also modelled based on the operating variables using regression analysis. The developed model was then verified using various statistical approaches. The results revealed that the operating variables of circular diamond sawblades can be precisely optimized by Taguchi approach for the Fc in rock sawing. The cut depth and peripheral speed were statistically determined as the significant operating variables affecting Fc. Furthermore, the modelling results showed that the proposed model can be effectively used for the prediction of Fc in practical applications.
Choi, Min S.; Meshik, Xenia; Mukherjee, Souvik; Farid, Sidra; Doan, Samuel; Covnot, Leigha; Dutta, Mitra; Stroscio, Michael A.
2015-11-01
ZnO quantum dots (QDs) are used in a variety of applications due to several desirable characteristics, including a wide band gap, luminescence, and biocompatibility. Wurtzite ZnO QDs also exhibit a spontaneous polarization along the growth axis, leading to large electric fields. In this work, ZnO QDs around 7 nm in diameter are synthesized using the sol-gel method. Their size and structure are confirmed using photoluminescence, Raman spectroscopy, atomic force microscopy, and transmission electron microscopy. Additionally, electrostatic force microscopy (EFM) is used to measure the amplitude change in the probe which is associated with the electric field produced by ZnO immobilized by layer-by-layer synthesis technique. The measured electrostatic field of 10 8 V/m is comparable to theoretically predicted value. Additionally, the strength of the electrostatic field is shown to depend on the orientation of the QD's c-axis. These results demonstrate a unique technique of quantifying ZnO's electric force using EFM.
Institute of Scientific and Technical Information of China (English)
WANG Guo-ye; LIU Zhao-du; MA Yue-feng; QI Zhi-quan
2007-01-01
Based on the dynamics of ABS-equipped vehicles during cornering braking,the electronic brakeforce distribution (EBD) control methods of ABS-equipped vehicles during cornering braking are proposed.According to the dynamics and the tire model under tire adhesion limit,the stability acceptance criteria of vehicles during cornering braking are proposed.According to the stability acceptance criteria and the ABS control,the EBD control methods of ABS-equipped vehicles during cornering braking are implemented by adjusting the threshold values of tires slip independently.The vehicle states during cornering braking at two typical initial velocities of the vehicle are analyzed by the EBD control methods,whose results indicate the EBD control methods can improve the braking performances of the vehicle during cornering braking comparing with the ABS control.
Static Kirchhoff Rods under the Action of External Forces: Integration via Runge-Kutta Method
Directory of Open Access Journals (Sweden)
Ademir L. Xavier Jr.
2014-01-01
at once Kirchhoff and filament reference system equations under appropriate initial boundary conditions. To show the application of the method, we display several numerical solutions for filaments including cases showing the effect of gravity.
Phonon excitation and instabilities in biased graphene nanoconstrictions
DEFF Research Database (Denmark)
Gunst, Tue; Lu, Jing Tao; Hedegård, Per;
2013-01-01
We investigate how a high current density perturbs the phonons in a biased graphene nanoconstriction coupled to semi-infinite electrodes. The coupling to electrode phonons, electrode electrons under bias, Joule heating, and current-induced forces is evaluated using first principles density...
Magnetization reversal in submicron disks: exchange biased vortices
Sort Viñas, Jordi; Hoffmann, Axel; Chung, S-H.; Buchanan, K. S.; Grimsditch, M.; Baró, M.D.; Dieny, B; Nogués i Sanmiquel, Josep
2005-01-01
Submicron, circular, ferromagnetic-antiferromagnetic dots exhibit different magnetization reversal mechanisms depending on the direction of the magnetic applied field. Shifted, constricted hysteresis loops, typical for vortex formation, are observed for fields along the exchange bias direction. However, for fields applied close to perpendicular to the exchange bias direction, magnetization reversal occurs via coherent rotation. Magnetic force microscopy imaging together with micromagnetic sim...
Does Monetary Policy Have Expansionary Bias with External Wealth?
Takamatsu, Satoko
2008-01-01
This paper investigates how the accumulation of external wealth affects a monetary policy. We demonstrate that though an expansionary bias emerges in a monetary policy, a fiscal method can eliminate such a bias.
Directory of Open Access Journals (Sweden)
I. I. Sergey
2005-01-01
Full Text Available The paper contains description of a simplified method for calculating closing-in of switch-gear flexible buses at short circuit. The developed method is based on integral and energy principles of mechanics. In order to increase accuracy of the calculation corrections factors are introduced in an explicit formula for calculation of maximum horizontal deviations. These factors have been obtained with the help of a computer program that realized numerical method for calculating closing-in of wires by flexible thread levels.Diagrams are constructed with the purpose to find ymax and criteria of electro-dynamic resistance of flexible buses (permissible impulse of electro-dynamic forces and current of electro-dynamic resistance is determined.
Nanonet Force Microscopy for Measuring Cell Forces.
Sheets, Kevin; Wang, Ji; Zhao, Wei; Kapania, Rakesh; Nain, Amrinder S
2016-07-12
The influence of physical forces exerted by or felt by cells on cell shape, migration, and cytoskeleton arrangement is now widely acknowledged and hypothesized to occur due to modulation of cellular inside-out forces in response to changes in the external fibrous environment (outside-in). Our previous work using the non-electrospinning Spinneret-based Tunable Engineered Parameters' suspended fibers has revealed that cells are able to sense and respond to changes in fiber curvature and structural stiffness as evidenced by alterations to focal adhesion cluster lengths. Here, we present the development and application of a suspended nanonet platform for measuring C2C12 mouse myoblast forces attached to fibers of three diameters (250, 400, and 800 nm) representing a wide range of structural stiffness (3-50 nN/μm). The nanonet force microscopy platform measures cell adhesion forces in response to symmetric and asymmetric external perturbation in single and cyclic modes. We find that contractility-based, inside-out forces are evenly distributed at the edges of the cell, and that forces are dependent on fiber structural stiffness. Additionally, external perturbation in symmetric and asymmetric modes biases cell-fiber failure location without affecting the outside-in forces of cell-fiber adhesion. We then extend the platform to measure forces of (1) cell-cell junctions, (2) single cells undergoing cyclic perturbation in the presence of drugs, and (3) cancerous single-cells transitioning from a blebbing to a pseudopodial morphology. PMID:27410747
Which forcing data errors matter most when modeling seasonal snowpacks?
Raleigh, M. S.; Lundquist, J. D.; Clark, M. P.
2014-12-01
High quality forcing data are critical when modeling seasonal snowpacks and snowmelt, but their quality is often compromised due to measurement errors or deficiencies in gridded data products (e.g., spatio-temporal interpolation, empirical parameterizations, or numerical weather model outputs). To assess the relative impact of errors in different meteorological forcings, many studies have conducted sensitivity analyses where errors (e.g., bias) are imposed on one forcing at a time and changes in model output are compared. Although straightforward, this approach only considers simplistic error structures and cannot quantify interactions in different meteorological forcing errors (i.e., it assumes a linear system). Here we employ the Sobol' method of global sensitivity analysis, which allows us to test how co-existing errors in six meteorological forcings (i.e., air temperature, precipitation, wind speed, humidity, incoming shortwave and longwave radiation) impact specific modeled snow variables (i.e., peak snow water equivalent, snowmelt rates, and snow disappearance timing). Using the Sobol' framework across a large number of realizations (>100000 simulations annually at each site), we test how (1) the type (e.g., bias vs. random errors), (2) distribution (e.g., uniform vs. normal), and (3) magnitude (e.g., instrument uncertainty vs. field uncertainty) of forcing errors impact key outputs from a physically based snow model (the Utah Energy Balance). We also assess the role of climate by conducting the analysis at sites in maritime, intermountain, continental, and tundra snow zones. For all outputs considered, results show that (1) biases in forcing data are more important than random errors, (2) the choice of error distribution can enhance the importance of specific forcings, and (3) the level of uncertainty considered dictates the relative importance of forcings. While the relative importance of forcings varied with snow variable and climate, the results broadly
Application and investigation of a bound for outcome reporting bias
Gamble Carrol; Williamson Paula R
2007-01-01
Abstract Background Direct empirical evidence for the existence of outcome reporting bias is accumulating and this source of bias is recognised as a potential threat to the validity of meta-analysis of randomised clinical trials. Methods A method for calculating the maximum bias in a meta-analysis due to publication bias is adapted for the setting where within-study selective non-reporting of outcomes is suspected, and compared to the alternative approach of missing data imputation. The prope...
Institute of Scientific and Technical Information of China (English)
张荣; 何雪明
2004-01-01
A numerical perturbation expansion method is developed, analysed and implemented for the numerical solution of a second-order initial-value problem. The differential equation in this problem exhibits cubic damping, a cubic restoring force and a decaying forcing-term which is periodic with constant frequency. The method is compared with the numerical method by Twizell [1]. In fact, the later is first perturbation approximate solution in the present paper.
The diagnostic performance of imaging methods in ARVC using the 2010 Task Force criteria
DEFF Research Database (Denmark)
Borgquist, Rasmus; Haugaa, Kristina H; Gilljam, Thomas;
2014-01-01
AIMS: This study evaluates the agreement between echocardiographic and cardiac magnetic resonance (CMR) imaging data, and the impact a discrepancy between the two may have on the clinical diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC). METHODS AND RESULTS: From the Nordic ARVC...
Moissenet, Florent; Chèze, Laurence; Dumas, Raphaël
2012-06-01
Inverse dynamics combined with a constrained static optimization analysis has often been proposed to solve the muscular redundancy problem. Typically, the optimization problem consists in a cost function to be minimized and some equality and inequality constraints to be fulfilled. Penalty-based and Lagrange multipliers methods are common optimization methods for the equality constraints management. More recently, the pseudo-inverse method has been introduced in the field of biomechanics. The purpose of this paper is to evaluate the ability and the efficiency of this new method to solve the muscular redundancy problem, by comparing respectively the musculo-tendon forces prediction and its cost-effectiveness against common optimization methods. Since algorithm efficiency and equality constraints fulfillment highly belong to the optimization method, a two-phase procedure is proposed in order to identify and compare the complexity of the cost function, the number of iterations needed to find a solution and the computational time of the penalty-based method, the Lagrange multipliers method and pseudo-inverse method. Using a 2D knee musculo-skeletal model in an isometric context, the study of the cost functions isovalue curves shows that the solution space is 2D with the penalty-based method, 3D with the Lagrange multipliers method and 1D with the pseudo-inverse method. The minimal cost function area (defined as the area corresponding to 5% over the minimal cost) obtained for the pseudo-inverse method is very limited and along the solution space line, whereas the minimal cost function area obtained for other methods are larger or more complex. Moreover, when using a 3D lower limb musculo-skeletal model during a gait cycle simulation, the pseudo-inverse method provides the lowest number of iterations while Lagrange multipliers and pseudo-inverse method have almost the same computational time. The pseudo-inverse method, by providing a better suited cost function and an
Holm, Håkan J.
2008-01-01
Beliefs in signals that reveal lies or truths are widespread. These signals may lead to a truth or lie detection bias if the probability that such a signal is perceived by the receiver is contingent on the truth value of the sender’s message. Such detection biases are analyzed theoretically in a bluffing game. The detection bias shrinks the equilibrium set to a unique non-pooling equilibrium, in which the better a player is at detecting lies the more often the opponent player will lie. With p...
Hamza Fadhila; Azouzi Mohamed Ali; Jarboui Anis
2014-01-01
This paper studies the role of governance mechanisms, CEO‟s cognitive characteristics and firms‟ financial features in justifying the CEO‟s escalatory behavior in firm‟s investment decision. This study aims to provide evidence as to whether managers consider the persuasive influence of governance mechanisms and the firm‟s financial indicators to persevere his initial investment decision while he notes a high level of commitment bias. The proposed model of this paper uses Bayesian Network Meth...
Microfluidic devices, systems, and methods for quantifying particles using centrifugal force
Schaff, Ulrich Y.; Sommer, Gregory J.; Singh, Anup K.
2015-11-17
Embodiments of the present invention are directed toward microfluidic systems, apparatus, and methods for measuring a quantity of cells in a fluid. Examples include a differential white blood cell measurement using a centrifugal microfluidic system. A method may include introducing a fluid sample containing a quantity of cells into a microfluidic channel defined in part by a substrate. The quantity of cells may be transported toward a detection region defined in part by the substrate, wherein the detection region contains a density media, and wherein the density media has a density lower than a density of the cells and higher than a density of the fluid sample. The substrate may be spun such that at least a portion of the quantity of cells are transported through the density media. Signals may be detected from label moieties affixed to the cells.
Domenico Fuoco
2012-01-01
In order to study and develop an economical solution to environmental pollution in water, a wide variety of materials have been investigated. Natural zeolites emerge from that research as the best in class of this category. Zeolites are natural materials which are relatively abundant and non biodegradable, economical and serve to perform processes of environmental remediation. This paper contains a full description of a new method to characterize the superficial properties of natural zeolites...
Energy Technology Data Exchange (ETDEWEB)
Yagi, Mamiko; Ito, Mitsuki; Shirakashi, Jun-ichi, E-mail: shrakash@cc.tuat.ac.jp [Department of Electrical and Electronic Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588 (Japan)
2015-07-07
We report a new method for fabrication of Ni nanogaps based on electromigration induced by a field emission current. This method is called “activation” and is demonstrated here using a current source with alternately reversing polarities. The activation procedure with alternating current bias, in which the current source polarity alternates between positive and negative bias conditions, is performed with planar Ni nanogaps defined on SiO{sub 2}/Si substrates at room temperature. During negative biasing, a Fowler-Nordheim field emission current flows from the source (cathode) to the drain (anode) electrode. The Ni atoms at the tip of the drain electrode are thus activated and then migrate across the gap from the drain to the source electrode. In contrast, in the positive bias case, the field emission current moves the activated atoms from the source to the drain electrode. These two procedures are repeated until the tunnel resistance of the nanogaps is successively reduced from 100 TΩ to 48 kΩ. Scanning electron microscopy and atomic force microscopy studies showed that the gap separation narrowed from approximately 95 nm to less than 10 nm because of the Ni atoms that accumulated at the tips of both the source and drain electrodes. These results show that the alternately biased activation process, which is a newly proposed atom transfer technique, can successfully control the tunnel resistance of the Ni nanogaps and is a suitable method for formation of ultrasmall nanogap structures.
Institute of Scientific and Technical Information of China (English)
Yu-wei Zhou; Igor Ying Zhang; Jian-ming Wu; An-an Wu; Xin Xu
2011-01-01
Benzene dimer (bz2) is the simplest prototype of the π-π interactions.Such interactions are ubiquitous in diverse areas of science and molecular engineering.In the present work,we have made assessment on some modern density functional methods including B97-D,BLYP-D3,M06-2X,XYG3,and force field models including CHARMM,AMBER,MM3,AMOEBA on six important interaction modes of bz2.Our results not only highlight the usefulness of these cost-effective methods,which can be used as economic substitutes of the expensive CCSD(T) for complex real-world systems,but also indicate their weakness in the description of the π-π interactions,which points to the future direction for further improvements.
Bootstrap bias-adjusted GMM estimators
Ramalho, Joaquim J.S.
2005-01-01
The ability of six alternative bootstrap methods to reduce the bias of GMM parameter estimates is examined in an instrumental variable framework using Monte Carlo analysis. Promising results were found for the two bootstrap estimators suggested in the paper.
DEFF Research Database (Denmark)
Paldam, Martin
censoring: selection by the size of estimate; SR3 selects the optimal combination of fit and size; and SR4 selects the first satisficing result. The last four SRs are steered by priors and result in bias. The MST and the FAT-PET have been developed for detection and correction of such bias. The simulations...... are made by data variation, while the model is the same. It appears that SR0 generates narrow funnels much at odds with observed funnels, while the other four funnels look more realistic. SR1 to SR4 give the mean a substantial bias that confirms the prior causing the bias. The FAT-PET MRA works well...
Introduction to Unconscious Bias
Schmelz, Joan T.
2010-05-01
We all have biases, and we are (for the most part) unaware of them. In general, men and women BOTH unconsciously devalue the contributions of women. This can have a detrimental effect on grant proposals, job applications, and performance reviews. Sociology is way ahead of astronomy in these studies. When evaluating identical application packages, male and female University psychology professors preferred 2:1 to hire "Brian” over "Karen” as an assistant professor. When evaluating a more experienced record (at the point of promotion to tenure), reservations were expressed four times more often when the name was female. This unconscious bias has a repeated negative effect on Karen's career. This talk will introduce the concept of unconscious bias and also give recommendations on how to address it using an example for a faculty search committee. The process of eliminating unconscious bias begins with awareness, then moves to policy and practice, and ends with accountability.
Directory of Open Access Journals (Sweden)
W. Terink
2009-08-01
Full Text Available In many climate impact studies hydrological models are forced with meteorological forcing data without an attempt to assess the quality of these forcing data. The objective of this study is to compare downscaled ERA15 (ECMWF-reanalysis data precipitation and temperature with observed precipitation and temperature and apply a bias correction to these forcing variables. The bias-corrected precipitation and temperature data will be used in another study as input for the Variable Infiltration Capacity (VIC model. Observations were available for 134 sub-basins throughout the Rhine basin at a temporal resolution of one day from the International Commission for the Hydrology of the Rhine basin (CHR. Precipitation is corrected by fitting the mean and coefficient of variation (CV of the observations. Temperature is corrected by fitting the mean and standard deviation of the observations. It seems that the uncorrected ERA15 is too warm and too wet for most of the Rhine basin. The bias correction leads to satisfactory results, precipitation and temperature differences decreased significantly. Corrections were largest during summer for both precipitation and temperature, and for September and October for precipitation only. Besides the statistics the correction method was intended to correct for, it is also found to improve the correlations for the fraction of wet days and lag-1 autocorrelations between ERA15 and the observations.
Directory of Open Access Journals (Sweden)
Phillips Carl V
2004-08-01
Full Text Available Abstract Background Publication bias, as typically defined, refers to the decreased likelihood of studies' results being published when they are near the null, not statistically significant, or otherwise "less interesting." But choices about how to analyze the data and which results to report create a publication bias within the published results, a bias I label "publication bias in situ" (PBIS. Discussion PBIS may create much greater bias in the literature than traditionally defined publication bias (the failure to publish any result from a study. The causes of PBIS are well known, consisting of various decisions about reporting that are influenced by the data. But its impact is not generally appreciated, and very little attention is devoted to it. What attention there is consists largely of rules for statistical analysis that are impractical and do not actually reduce the bias in reported estimates. PBIS cannot be reduced by statistical tools because it is not fundamentally a problem of statistics, but rather of non-statistical choices and plain language interpretations. PBIS should be recognized as a phenomenon worthy of study – it is extremely common and probably has a huge impact on results reported in the literature – and there should be greater systematic efforts to identify and reduce it. The paper presents examples, including results of a recent HIV vaccine trial, that show how easily PBIS can have a large impact on reported results, as well as how there can be no simple answer to it. Summary PBIS is a major problem, worthy of substantially more attention than it receives. There are ways to reduce the bias, but they are very seldom employed because they are largely unrecognized.
Mishra, Anil V; Umaru B. Conteh
2014-01-01
This paper constructs the float adjusted measure of home bias and explores the determinants of bond home bias by employing the International Monetary Fund's high quality dataset (2001 to 2009) on cross-border bond investment. The paper finds that Australian investors' prefer investing in countries with higher economic development and more developed bond markets. Exchange rate volatility appears to be an impediment for cross-border bond investment. Investors prefer investing in countries with ...
EVIDENCE OF NATIONALISTIC BIAS IN MUAYTHAI
Directory of Open Access Journals (Sweden)
Tony D. Myers
2006-07-01
Full Text Available MuayThai is a combat sport with a growing international profile but limited research conducted into judging practices and processes. Problems with judging of other subjectively judged combat sports have caused controversy at major international tournaments that have resulted in changes to scoring methods. Nationalistic bias has been central to these problems and has been identified across a range of sports. The aim of this study was to examine nationalistic bias in MuayThai. Data were collected from the International Federation of MuayThai Amateur (IFMA World Championships held in Almaty, Kazakhstan September 2003 and comprised of tournament results from 70 A-class MuayThai bouts each judged by between five and nine judges. Bouts examined featured 62 competitors from 21 countries and 25 judges from 11 countries. Results suggested that nationalistic bias was evident. The bias observed equated to approximately one round difference between opposing judges over the course of a bout (a mean of 1.09 (SE=0.50 points difference between judges with opposing affilations. The number of neutral judges used meant that this level of bias generally did not influence the outcome of bouts. Future research should explore other ingroup biases, such as nearest neighbour bias and political bias as well as investigating the feasibility adopting an electronic scoring system
Janet Gale Stotsky
1996-01-01
This paper examines the nature of gender bias in tax systems. Gender bias takes both explicit and implicit forms. Explicit gender bias is found in many personal income tax systems. Several countries, especially those in Western Europe, have undertaken to eliminate explicit gender bias in recent years. It is more difficult to identify implicit gender bias, since this depends in large part on value judgments as to desirable social and economic behavior. Implicit gender bias has also been a targ...
Analysis of microstructural evolution driven by production bias
DEFF Research Database (Denmark)
Woo, C.H.; Semenov, A.A.; Singh, B.N.
1993-01-01
The concept of production bias was first considered in the preceding workshop in this series at Silkeborg in 1989. Since then, much work has been done to investigate the validity of the concept, and its usefulness in complementing the current theory of microstructure evolution based solely...... on the sink bias (e.g., dislocation bias) as a driving force. Comparison of the theory with experimental results clearly supports the concept. The present paper reviews and summarizes these investigations, and arrives at the following conclusions: a) the concept of production bias is consistent...
Pan, Wenxiao; Bao, Jie; Tartakovsky, Alexandre
2013-11-01
A Continuous Boundary Force (CBF) method was developed for implementing Robin (Navier) boundary condition (BC) that can describe no-slip or slip conditions (slip length from zero to infinity) at the fluid-solid interface. In the CBF method the Robin BC is replaced by a homogeneous Neumann BC and an additional volumetric source term in the governing momentum equation. The formulation is derived based on an approximation of the sharp boundary with a diffuse interface of finite thickness, across which the BC is reformulated by means of a smoothed characteristic function. The CBF method is easy to be implemented in Lagrangian particle-based methods. We first implemented it in smoothed particle hydrodynamics (SPH) to solve numerically the Navier-Stokes equations subject to spatial-independent or dependent Robin BC in two and three dimensions. The numerical accuracy and convergence is examined through comparisons with the corresponding finite difference or finite element solutions. The CBF method is further implemented in smoothed dissipative particle dynamics (SDPD), a mesoscale scheme, for modeling slip flows commonly existent in micro/nano channels and microfluidic devices. The authors acknowledge the funding support by the ASCR Program of the Office of Science, U.S. Department of Energy.
Wen, L; Wang, T M; Wu, G H; Liang, J H
2012-09-01
We implement a mackerel (Scomber scombrus) body-shaped robot, programmed to display the three most typical body/caudal fin undulatory kinematics (i.e. anguilliform, carangiform and thunniform), in order to biomimetically investigate hydrodynamic issues not easily tackled experimentally with live fish. The robotic mackerel, mounted on a servo towing system and initially at rest, can determine its self-propelled speed by measuring the external force acting upon it and allowing for the simultaneous measurement of power, flow field and self-propelled speed. Experimental results showed that the robotic swimmer with thunniform kinematics achieved a faster final swimming speed (St = 0.424) relative to those with carangiform (St = 0.43) and anguilliform kinematics (St = 0.55). The thrust efficiency, estimated from a digital particle image velocimetry (DPIV) flow field, showed that the robotic swimmer with thunniform kinematics is more efficient (47.3%) than those with carangiform (31.4%) and anguilliform kinematics (26.6%). Furthermore, the DPIV measurements illustrate that the large-scale characteristics of the flow pattern generated by the robotic swimmer with both anguilliform and carangiform kinematics were wedge-like, double-row wake structures. Additionally, a typical single-row reverse Karman vortex was produced by the robotic swimmer using thunniform kinematics. Finally, we discuss this novel force-feedback-controlled experimental method, and review the relative self-propelled hydrodynamic results of the robot when utilizing the three types of undulatory kinematics. PMID:22556135
澤田, 秀夫
The aerodynamic performance of an AGARD-B model, as an example of a winged model, was measured in a low-speed wind tunnel equipped with the JAXA 60cm Magnetic Suspension and Balance System (MSBS). The flow speed was in the range between 25m/s and 35m/s, and the angle of attack and the yaw angle were in the range of [- 8, 4] and [- 3, 3] degrees, respectively. Six components of the aerodynamic force were evaluated by using the control coil currents of the MSBS. In evaluating the drag, the effect of the lift on the drag must be evaluated at MSBS when the lift is much larger than drag. A new evaluation method for drag and lift was proposed and was examined successfully by subjecting the model to the same loads as in the wind tunnel test. The drag coefficient at zero lift and the derivatives of the lift and pitching moment coefficient with respect to the angle of attack were evaluated and compared with other source data sets. The obtained data agreed well with the corresponding values of the other sources. The side force, yawing moment and rolling moment coefficients were also evaluated on the basis of corresponding calibration test results, and reasonable results were obtained, although they could not be compared due to the lack of reliable data sets.
Bias-Correction in Vector Autoregressive Models: A Simulation Study
Directory of Open Access Journals (Sweden)
Tom Engsted
2014-03-01
Full Text Available We analyze the properties of various methods for bias-correcting parameter estimates in both stationary and non-stationary vector autoregressive models. First, we show that two analytical bias formulas from the existing literature are in fact identical. Next, based on a detailed simulation study, we show that when the model is stationary this simple bias formula compares very favorably to bootstrap bias-correction, both in terms of bias and mean squared error. In non-stationary models, the analytical bias formula performs noticeably worse than bootstrapping. Both methods yield a notable improvement over ordinary least squares. We pay special attention to the risk of pushing an otherwise stationary model into the non-stationary region of the parameter space when correcting for bias. Finally, we consider a recently proposed reduced-bias weighted least squares estimator, and we find that it compares very favorably in non-stationary models.
Bias Correction for Alternating Iterative Maximum Likelihood Estimators
Institute of Scientific and Technical Information of China (English)
Gang YU; Wei GAO; Ningzhong SHI
2013-01-01
In this paper,we give a definition of the alternating iterative maximum likelihood estimator (AIMLE) which is a biased estimator.Furthermore we adjust the AIMLE to result in asymptotically unbiased and consistent estimators by using a bootstrap iterative bias correction method as in Kuk (1995).Two examples and simulation results reported illustrate the performance of the bias correction for AIMLE.
Caetano, J V; Percin, M; van Oudheusden, B W; Remes, B; de Wagter, C; de Croon, G C H E; de Visser, C C
2015-10-01
An accurate knowledge of the unsteady aerodynamic forces acting on a bio-inspired, flapping-wing micro air vehicle (FWMAV) is crucial in the design development and optimization cycle. Two different types of experimental approaches are often used: determination of forces from position data obtained from external optical tracking during free flight, or direct measurements of forces by attaching the FWMAV to a force transducer in a wind-tunnel. This study compares the quality of the forces obtained from both methods as applied to a 17.4 gram FWMAV capable of controlled flight. A comprehensive analysis of various error sources is performed. The effects of different factors, e.g., measurement errors, error propagation, numerical differentiation, filtering frequency selection, and structural eigenmode interference, are assessed. For the forces obtained from free flight experiments it is shown that a data acquisition frequency below 200 Hz and an accuracy in the position measurements lower than ± 0.2 mm may considerably hinder determination of the unsteady forces. In general, the force component parallel to the fuselage determined by the two methods compares well for identical flight conditions; however, a significant difference was observed for the forces along the stroke plane of the wings. This was found to originate from the restrictions applied by the clamp to the dynamic oscillations observed in free flight and from the structural resonance of the clamped FWMAV structure, which generates loads that cannot be distinguished from the external forces. Furthermore, the clamping position was found to have a pronounced influence on the eigenmodes of the structure, and this effect should be taken into account for accurate force measurements. PMID:26292289
Caetano, J V; Percin, M; van Oudheusden, B W; Remes, B; de Wagter, C; de Croon, G C H E; de Visser, C C
2015-08-20
An accurate knowledge of the unsteady aerodynamic forces acting on a bio-inspired, flapping-wing micro air vehicle (FWMAV) is crucial in the design development and optimization cycle. Two different types of experimental approaches are often used: determination of forces from position data obtained from external optical tracking during free flight, or direct measurements of forces by attaching the FWMAV to a force transducer in a wind-tunnel. This study compares the quality of the forces obtained from both methods as applied to a 17.4 gram FWMAV capable of controlled flight. A comprehensive analysis of various error sources is performed. The effects of different factors, e.g., measurement errors, error propagation, numerical differentiation, filtering frequency selection, and structural eigenmode interference, are assessed. For the forces obtained from free flight experiments it is shown that a data acquisition frequency below 200 Hz and an accuracy in the position measurements lower than ± 0.2 mm may considerably hinder determination of the unsteady forces. In general, the force component parallel to the fuselage determined by the two methods compares well for identical flight conditions; however, a significant difference was observed for the forces along the stroke plane of the wings. This was found to originate from the restrictions applied by the clamp to the dynamic oscillations observed in free flight and from the structural resonance of the clamped FWMAV structure, which generates loads that cannot be distinguished from the external forces. Furthermore, the clamping position was found to have a pronounced influence on the eigenmodes of the structure, and this effect should be taken into account for accurate force measurements.
Probability biases as Bayesian inference
Directory of Open Access Journals (Sweden)
Andre; C. R. Martins
2006-11-01
Full Text Available In this article, I will show how several observed biases in human probabilistic reasoning can be partially explained as good heuristics for making inferences in an environment where probabilities have uncertainties associated to them. Previous results show that the weight functions and the observed violations of coalescing and stochastic dominance can be understood from a Bayesian point of view. We will review those results and see that Bayesian methods should also be used as part of the explanation behind other known biases. That means that, although the observed errors are still errors under the be understood as adaptations to the solution of real life problems. Heuristics that allow fast evaluations and mimic a Bayesian inference would be an evolutionary advantage, since they would give us an efficient way of making decisions. %XX In that sense, it should be no surprise that humans reason with % probability as it has been observed.
Institute of Scientific and Technical Information of China (English)
无
2009-01-01
A series of theoretical approaches,including conventional FF03 and FF03-based polarization model,as well as the generalized energy-based fragmentation(GEBF) quantum chemistry method,have been applied to investigate the interactions between acetate ion(CH3COO-) and the α-subunit of human adult hemoglobin(designated as Hb-α) at four binding sites(Lys16,Lys90,Arg92,and Lys127),respectively.The FF03-based polarizable force fields show that the interaction energies between the CH3COO-group and Hb-α follow the trend of Arg92>Lys127>Lys90>Lys16.The complexation of CH3COO-with Hb-α is governed by the long-range electrostatic interactions and steric effect.
Institute of Scientific and Technical Information of China (English)
YAN XiuFen; JIANG Nan; MA Jing
2009-01-01
A series of theoretical approaches,including conventional FF03 and FF03-based polarization model,as well as the generalized energy-based fragmentation (GEBF) quantum chemistry method,have been applied to investigate the interactions between acetate ion (CH_3COO~-) and the α-subunit of human adult hemoglobin (designated as Hb-α) at four binding sites (Lys16,Lys90,Arg92,and Lys127),respectively.The FF03-based polarizable force fields show that the interaction energies between the CH_3COO~-group and Hb-α follow the trend of Arg92＞Lys127＞Lys90＞Lys16.The complexation of CH_3COO~-with Hb-α is governed by the long-range electrostatic interactions and steric effect.
Energy Technology Data Exchange (ETDEWEB)
Lima, B.L.S. [Laboratório de Sensores Óticos, Escola Politécnica, Universidade de São Paulo, SP (Brazil); Maximino, F.L. [Laboratório de Materiais Magnéticos, Instituto de Física, Universidade de São Paulo, CEP:05314-970 São Paulo, SP (Brazil); Santos, J.C. [Laboratório de Sensores Óticos, Escola Politécnica, Universidade de São Paulo, SP (Brazil); Santos, A.D., E-mail: adsantos@if.usp.br [Laboratório de Materiais Magnéticos, Instituto de Física, Universidade de São Paulo, CEP:05314-970 São Paulo, SP (Brazil)
2015-12-01
This paper presents a method based on the Atomic Force Microscopy technique for direct measurement of magnetostriction coefficient of amorphous Tb–Co films deposited on Si(100) substrate. The magnetostriction coefficient of the film is determined by AFM measuring the deflection of the sample when applying a magnetic field. In order to maximize the deflection of the sample, in-plane magnetic anisotropy was induced by heat treatment under a magnetic field of 5 kOe. The value obtained for the saturation magnetostriction is 204×10{sup −6} for the Tb{sub 23}Co{sub 77} film. - Highlights: • Measurement of magnetostriction coefficient using AFM. • Tb–Co thin films produced by magnetron sputtering. • Magnetostriction characterization of magnetic thin films on nonmagnetic substrates.
International Nuclear Information System (INIS)
A simple calibration method is described for the determination of surface energy by atomic force microscopy (AFM) pull-off force measurements on nanostructured surfaces covered with molecularly thin liquid films. The method is based on correlating pull-off forces measured in arbitrary units on a nanostructured surface with pull-off forces measured on macroscopically smooth dip-coated gauge surfaces with known surface energy. The method avoids the need for complex calibration of the AFM cantilever stiffness and the determination of the radius of curvature of the AFM tip. Both of the latter measurements are associated with indirect and less accurate measurements of surface energy based on various contact mechanics adhesion models.
McCausland, Jeffrey; Withanage, Sajeevi; Mallik, Robert; Lyuksyutov, Sergei
A conductive un-biased AFM tip oscillating above p-type or un-doped Si (100) treated with toluene, butan-2-ol, and propan-2-ol creates nanostructures ranging in height from 1-100 nm. The tip was oscillated in ambient conditions (30-70% Rel. Humidity) at frequencies in the 102 kHz range. It was repeatable with various concentrations of solvent in aqueous solution. It is suggested that mechanical oscillations of the AFM tip polarizes the solvent molecules deposited on the surface resulting in electron transfer from the tip to the surface followed by feature formation. This process effectively creates an electrochemical cell at the microscopic level and the miscibility of the solvents is the key to enabling the process. Species which ionize during the process may be consumed in irreversible reactions whereas the alcohols act as catalysts and are not consumed. The influence of boron defects in the Si substrates is also discussed. It appears that the observed oxidation is different from all other similar reported phenomena including local anodic oxidation, and chemo-mechanical lithographic techniques utilizing AFM.
Searching for transition paths in multidimensional space with a fixed repulsive bias potential
Trushin, O. S.; Salo, P.; Ala-Nissila, T.; Ying, S. C.
2004-01-01
An efficient method for searching for transition paths in a multidimensional configuration space is proposed. It is based on using a fixed, locally repulsive bias potential, which forces the system to move from a given initial state to a different final state. This simple method is very effective in determining nearby configurations and possible transition paths for many-particle systems. Once the approximate transition paths are known, the corresponding activation energies can be computed using, e.g., the nudged elastic band method. The usefulness of the present method is demonstrated for both classical and quantum-mechanical systems.
Chang, Le; Ishikawa, Takeshi; Kuwata, Kazuo; Takada, Shoji
2013-05-30
Accurate computational estimate of the protein-ligand binding affinity is of central importance in rational drug design. To improve accuracy of the molecular mechanics (MM) force field (FF) for protein-ligand simulations, we use a protein-specific FF derived by the fragment molecular orbital (FMO) method and by the restrained electrostatic potential (RESP) method. Applying this FMO-RESP method to two proteins, dodecin, and lysozyme, we found that protein-specific partial charges tend to differ more significantly from the standard AMBER charges for isolated charged atoms. We did not see the dependence of partial charges on the secondary structure. Computing the binding affinities of dodecin with five ligands by MM PBSA protocol with the FMO-RESP charge set as well as with the standard AMBER charges, we found that the former gives better correlation with experimental affinities than the latter. While, for lysozyme with five ligands, both charge sets gave similar and relatively accurate estimates of binding affinities. PMID:23420697
International Nuclear Information System (INIS)
An accurate experimental method is proposed for on-spot calibration of the measurement sensitivities of multiple micro-cantilever dynamic modes in atomic force microscopy. One of the key techniques devised for this method is a reliable contact detection mechanism that detects the tip-surface contact instantly. At the contact instant, the oscillation amplitude of the tip deflection, converted to that of the deflection signal in laser reading through the measurement sensitivity, exactly equals to the distance between the sample surface and the cantilever base position. Therefore, the proposed method utilizes the recorded oscillation amplitude of the deflection signal and the base position of the cantilever at the contact instant for the measurement sensitivity calibration. Experimental apparatus along with various signal processing and control modules was realized to enable automatic and rapid acquisition of multiple sets of data, with which the calibration of a single dynamic mode could be completed in less than 1 s to suppress the effect of thermal drift and measurement noise. Calibration of the measurement sensitivities of the first and second dynamic modes of three micro-cantilevers having distinct geometries was successfully demonstrated. The dependence of the measurement sensitivity on laser spot location was also experimentally investigated. Finally, an experiment was performed to validate the calibrated measurement sensitivity of the second dynamic mode of a micro-cantilever.
DEFF Research Database (Denmark)
Jensen, Henning Tarp; Robinson, Sherman; Tarp, Finn
The measurement issue is the key issue in the literature on trade policy-induced agri-cultural price incentive bias. This paper introduces a general equilibrium effective rate of protection (GE-ERP) measure, which extends and generalizes earlier partial equilibrium nominal protection measures....... For the 15 sample countries, the results indicate that the agricultural price incentive bias, which was generally perceived to exist during the 1980s, was largely eliminated during the 1990s. The results also demonstrate that general equilibrium effects and country-specific characteristics - including trade...... shares and intersectoral linkages - are crucial for determining the sign and magnitude of trade policy bias. The GE-ERP measure is therefore uniquely suited to capture the full impact of trade policies on agricultural price incentives. A Monte Carlo procedure confirms that the results are robust...
Statistical framework for estimating GNSS bias
Vierinen, Juha; Rideout, William C; Erickson, Philip J; Norberg, Johannes
2015-01-01
We present a statistical framework for estimating global navigation satellite system (GNSS) non-ionospheric differential time delay bias. The biases are estimated by examining differences of measured line integrated electron densities (TEC) that are scaled to equivalent vertical integrated densities. The spatio-temporal variability, instrumentation dependent errors, and errors due to inaccurate ionospheric altitude profile assumptions are modeled as structure functions. These structure functions determine how the TEC differences are weighted in the linear least-squares minimization procedure, which is used to produce the bias estimates. A method for automatic detection and removal of outlier measurements that do not fit into a model of receiver bias is also described. The same statistical framework can be used for a single receiver station, but it also scales to a large global network of receivers. In addition to the Global Positioning System (GPS), the method is also applicable to other dual frequency GNSS s...
Calculation method of internal forces in herringbone micropile%人字形微型桩内力计算方法
Institute of Scientific and Technical Information of China (English)
施艳秋; 郑静; 吕昌明
2015-01-01
Among existing calculation methods for micropiles internal force,the upper structure was assumed as a steel frame and the sliding surface as a fixed support transfering moment and shear while the lower structure as an elastic foundation beam. In this paper,the selected micropiles were calculated as a composite structure. The deformation coordination at the sliding surface was considered,and the displacement and the rotation of the lower structure were used as those of the bearings for the upper structure. T he effect of the displacement on the internal force was studied. Based on the FLAC3D program,a simplified model was established to simulate the micropiles. T he internal force and the moment distribution were obtained with this model. W ith consideration of the deformation coordination at the sliding surface,the results were more closed to the results of numerical simulation.%基于弹性地基梁的微型桩内力计算方法中有一种是假定上部为钢架，滑面处为固定支座，传递弯矩和剪力，滑面以下桩体按弹性地基梁法计算。本文所选微型桩同样采用组合结构计算，同时考虑滑面处变形协调，把弹性地基梁的位移和转角作为上部结构的支座位移，考虑位移对内力的影响。针对微型桩滑面处弯矩，基于 FLAC3 D程序，建立简化的微型桩数值计算模型，提取桩的内力并绘制弯矩图，数值模拟结果与考虑变形协调后的弯矩图更接近。
Colin, Pierre; Kravtsov, A V; Colin, Pedro; Klypin, Anatoly; Kravtsov, Andrey V.
2000-01-01
We use N-body simulations to study the velocity bias of dark matter halos, the difference in the velocity fields of dark matter and halos, in a flat low- density LCDM model. The high force, 2kpc/h, and mass, 10^9Msun/h, resolution allows dark matter halos to survive in very dense environments of groups and clusters making it possible to use halos as galaxy tracers. We find that the velocity bias pvb measured as a ratio of pairwise velocities of the halos to that of the dark matter evolves with time and depends on scale. At high redshifts (z ~5) halos move generally faster than the dark matter almost on all scales: pvb(r)~1.2, r>0.5Mpc/h. At later moments the bias decreases and gets below unity on scales less than r=5Mpc/h: pvb(r)~(0.6-0.8) at z=0. We find that the evolution of the pairwise velocity bias follows and probably is defined by the spatial antibias of the dark matter halos at small scales. One-point velocity bias b_v, defined as the ratio of the rms velocities of halos and dark matter, provides a mo...
Electrostatically biased binding of kinesin to microtubules.
Directory of Open Access Journals (Sweden)
Barry J Grant
2011-11-01
Full Text Available The minimum motor domain of kinesin-1 is a single head. Recent evidence suggests that such minimal motor domains generate force by a biased binding mechanism, in which they preferentially select binding sites on the microtubule that lie ahead in the progress direction of the motor. A specific molecular mechanism for biased binding has, however, so far been lacking. Here we use atomistic Brownian dynamics simulations combined with experimental mutagenesis to show that incoming kinesin heads undergo electrostatically guided diffusion-to-capture by microtubules, and that this produces directionally biased binding. Kinesin-1 heads are initially rotated by the electrostatic field so that their tubulin-binding sites face inwards, and then steered towards a plus-endwards binding site. In tethered kinesin dimers, this bias is amplified. A 3-residue sequence (RAK in kinesin helix alpha-6 is predicted to be important for electrostatic guidance. Real-world mutagenesis of this sequence powerfully influences kinesin-driven microtubule sliding, with one mutant producing a 5-fold acceleration over wild type. We conclude that electrostatic interactions play an important role in the kinesin stepping mechanism, by biasing the diffusional association of kinesin with microtubules.
Contextual modulation of biases in face recognition.
Directory of Open Access Journals (Sweden)
Fatima Maria Felisberti
Full Text Available BACKGROUND: The ability to recognize the faces of potential cooperators and cheaters is fundamental to social exchanges, given that cooperation for mutual benefit is expected. Studies addressing biases in face recognition have so far proved inconclusive, with reports of biases towards faces of cheaters, biases towards faces of cooperators, or no biases at all. This study attempts to uncover possible causes underlying such discrepancies. METHODOLOGY AND FINDINGS: Four experiments were designed to investigate biases in face recognition during social exchanges when behavioral descriptors (prosocial, antisocial or neutral embedded in different scenarios were tagged to faces during memorization. Face recognition, measured as accuracy and response latency, was tested with modified yes-no, forced-choice and recall tasks (N = 174. An enhanced recognition of faces tagged with prosocial descriptors was observed when the encoding scenario involved financial transactions and the rules of the social contract were not explicit (experiments 1 and 2. Such bias was eliminated or attenuated by making participants explicitly aware of "cooperative", "cheating" and "neutral/indifferent" behaviors via a pre-test questionnaire and then adding such tags to behavioral descriptors (experiment 3. Further, in a social judgment scenario with descriptors of salient moral behaviors, recognition of antisocial and prosocial faces was similar, but significantly better than neutral faces (experiment 4. CONCLUSION: The results highlight the relevance of descriptors and scenarios of social exchange in face recognition, when the frequency of prosocial and antisocial individuals in a group is similar. Recognition biases towards prosocial faces emerged when descriptors did not state the rules of a social contract or the moral status of a behavior, and they point to the existence of broad and flexible cognitive abilities finely tuned to minor changes in social context.
Anderson, L. R.; Miller, R. D.
1979-01-01
The LOADS computer program L218 which calculates dynamic load coefficient matrices utilizing the force summation method is described. The load equations are derived for a flight vehicle in straight and level flight and excited by gusts and/or control motions. In addition, sensor equations are calculated for use with an active control system. The load coefficient matrices are calculated for the following types of loads: (1) translational and rotational accelerations, velocities, and displacements; (2) panel aerodynamic forces; (3) net panel forces; and (4) shears, bending moments, and torsions.
Institute of Scientific and Technical Information of China (English)
Ma Yingkun; Xie Shilin; Zhang Xinong; Luo Yajun
2013-01-01
A hybrid calibration approach based on support vector machines (SVM) is proposed to characterize nonlinear cross coupling of multi-dimensional transducer.It is difficult to identify these unknown nonlinearities and crosstalk just with a single conventional calibration approach.In this paper,a hybrid model comprising calibration matrix and SVM model for calibrating linearity and nonlinearity respectively is built up.The calibration matrix is determined by linear artificial neural network (ANN),and the SVM is used to compensate for the nonlinear cross coupling among each dimension.A simulation of the calibration of a multi-dimensional sensor is conducted by the SVM hybrid calibration method,which is then utilized to calibrate a six-component force/torque transducer of wind tunnel balance.From the calibrating results,it can be indicated that the SVM hybrid calibration method has improved the calibration accuracy significantly without increasing data samples,compared with calibration matrix.Moreover,with the calibration matrix,the hybrid model can provide a basis for the design of transducers.
Huang, Xing; Xin, Kun; Li, Xiu-zhen; Wang, Xue-ping; Ren, Lin-jing; Li, Xi-zhi; Yan, Zhong-zheng
2015-05-01
According to the interpreted results of three satellite images of Dongzhai Harbour obtained in 1988, 1998 and 2009, the changes of landscape pattern and the differences of its driving forces of mangrove forest in Dongzhai Harbour were analyzed with a patch-based method on spatial distribution dynamics. The results showed that the areas of mangrove forest in 1988, 1998 and 2009 were 1809.4, 1738.7 and 1608.2 hm2 respectively, which presented a trend of decrease with enhanced degree of landscape fragmentation. The transformations among different landscape types indicated that the mangrove, agricultural land and forest land were mainly changed into built-up land and aquaculture pond. The statistical results obtained from three different methods, i.e., accumulative counting, percentage counting and main transformation route counting, showed that natural factors were the main reason for the changes of patch number, responsible for 58.6%, 72.2% and 72.1% of patch number change, respectively, while the percentages of patch area change induced by human activities were 70.4%, 70.3% and 76.4%, respectively, indicating that human activities were the primary factors of the change of patch areas.
Wijk, van, M.J.; Krut, S.; Pierrot, F.; J. L. Herder
2011-01-01
This paper proposes a generic method for deriving the general shaking force balance conditions of parallel manipulators. Instead of considering the balancing of a parallel manipulator link-by-link or leg-by-leg, the architecture is considered altogether. The first step is to write the linear momentum of each element. The second step is to substitute the derivatives of the loop equations, by which the general force balance conditions are obtained. Subsequently specific kinematic conditions are...
On System-Dependent Sources of Uncertainty and Bias in Ultrasonic Quantitative Shear-Wave Imaging.
Deng, Yufeng; Rouze, Ned C; Palmeri, Mark L; Nightingale, Kathryn R
2016-03-01
Ultrasonic quantitative shear-wave imaging methods have been developed over the last decade to estimate tissue elasticity by measuring the speed of propagating shear waves following acoustic radiation force excitation. This work discusses eight sources of uncertainty and bias arising from ultrasound system-dependent parameters in ultrasound shear-wave speed (SWS) measurements. Each of the eight sources of error is discussed in the context of a linear, isotropic, elastic, homogeneous medium, combining previously reported analyses with Field II simulations, full-wave 2-D acoustic propagation simulations, and experimental studies. Errors arising from both spatial and temporal sources lead to errors in SWS measurements. Arrival time estimation noise, speckle bias, hardware fluctuations, and phase aberration cause uncertainties (variance) in SWS measurements, while pulse repetition frequency (PRF) and beamforming errors, as well as coupling medium sound speed mismatch, cause biases in SWS measurements (accuracy errors). Calibration of the sources of bias is an important step in the development of shear-wave imaging systems. In a well-calibrated system, where the sources of bias are minimized, and averaging over a region of interest (ROI) is employed to reduce the sources of uncertainty, an SWS error can be expected. PMID:26886980
Measuring agricultural policy bias
DEFF Research Database (Denmark)
Jensen, Henning Tarp; Robinson, Sherman; Tarp, Finn
2010-01-01
Measurement is a key issue in the literature on price incentive bias induced by trade policy. We introduce a general equilibrium measure of the relative effective rate of protection, which generalizes earlier protection measures. For our fifteen sample countries, results indicate...... protection measure is therefore uniquely suited to capture the full impact of trade policies on relative agricultural price incentives....
Directory of Open Access Journals (Sweden)
Dirk Reith
2013-09-01
Full Text Available Molecular modeling is an important subdomain in the field of computational modeling, regarding both scientific and industrial applications. This is because computer simulations on a molecular level are a virtuous instrument to study the impact of microscopic on macroscopic phenomena. Accurate molecular models are indispensable for such simulations in order to predict physical target observables, like density, pressure, diffusion coefficients or energetic properties, quantitatively over a wide range of temperatures. Thereby, molecular interactions are described mathematically by force fields. The mathematical description includes parameters for both intramolecular and intermolecular interactions. While intramolecular force field parameters can be determined by quantum mechanics, the parameterization of the intermolecular part is often tedious. Recently, an empirical procedure, based on the minimization of a loss function between simulated and experimental physical properties, was published by the authors. Thereby, efficient gradient-based numerical optimization algorithms were used. However, empirical force field optimization is inhibited by the two following central issues appearing in molecular simulations: firstly, they are extremely time-consuming, even on modern and high-performance computer clusters, and secondly, simulation data is affected by statistical noise. The latter provokes the fact that an accurate computation of gradients or Hessians is nearly impossible close to a local or global minimum, mainly because the loss function is flat. Therefore, the question arises of whether to apply a derivative-free method approximating the loss function by an appropriate model function. In this paper, a new Sparse Grid-based Optimization Workflow (SpaGrOW is presented, which accomplishes this task robustly and, at the same time, keeps the number of time-consuming simulations relatively small. This is achieved by an efficient sampling procedure
Institute of Scientific and Technical Information of China (English)
张伟; 荣伟彬; 王乐锋; 路遥; 孙立宁
2015-01-01
针对保偏光纤耦合器熔融拉锥制造过程中拉力控制问题,提出一种新的计算机在线拉力控制方法. 拉力控制系统由计算机、拉伸机构、圆光栅及控制电路组成,通过检测光纤支架的旋转角度、改变线圈中的电流,控制永磁铁与线圈间的电磁力,实现对拉伸力的实时控制. 分析电磁力和拉力的关系,建立永磁铁和线圈的三维有限元模型,确定永磁铁的运动轨迹,并对通电线圈的磁场分布和电磁力进行仿真,得到线圈中的电流、支架旋转角度和拉力的关系式. 仿真结果表明拉力控制良好,控制误差约为1.03%.%According to the problem of drawing force control in the fused biconical tapering process of polarization maintaining fiber ( PMF ) coupler, an online computer control method of drawing force is presented, which includes the computer, drawing mechanism, rotary position encoders and a control circuit. By detecting the rotation angle of fiber clamp, the electro-magnetic force can be controlled through changing the coil current, and the real-time control of drawing force is realized. Firstly, the relationship between the electromagnetic force and drawing force is analyzed, a 3D finite element model of the permanent magnet and the coil is established, and a trajectory equation describing the permanent magnet is obtained. Then, by simulation of the magnetic field and the electro-magnetic force around the coil, the relationship among the coil current, the rotation angle of fiber clamp and the drawing force is determined. At last, by simulation, the drawing force is controlled within an error of 1.03%.
Li, R.; Wang, S.-Y.; Gillies, R. R.
2016-04-01
Large biases associated with climate projections are problematic when it comes to their regional application in the assessment of water resources and ecosystems. Here, we demonstrate a method that can reduce systematic biases in regional climate projections. The global and regional climate models employed to demonstrate the technique are the Community Climate System Model (CCSM) and the Weather Research and Forecasting (WRF) model. The method first utilized a statistical regression technique and a global reanalysis dataset to correct biases in the CCSM-simulated variables (e.g., temperature, geopotential height, specific humidity, and winds) that are subsequently used to drive the WRF model. The WRF simulations were conducted for the western United States and were driven with (a) global reanalysis, (b) original CCSM, and (c) bias-corrected CCSM data. The bias-corrected CCSM data led to a more realistic regional climate simulation of precipitation and associated atmospheric dynamics, as well as snow water equivalent (SWE), in comparison to the original CCSM-driven WRF simulation. Since most climate applications rely on existing global model output as the forcing data (i.e., they cannot re-run or change the global model), which often contain large biases, this method provides an effective and economical tool to reduce biases in regional climate downscaling simulations of water resource variables.
Mei, Chuh; Shen, Mo-How
1987-01-01
Multiple-mode nonlinear forced vibration of a beam was analyzed by the finite element method. Inplane (longitudinal) displacement and inertia (IDI) are considered in the formulation. By combining the finite element method and nonlinear theory, more realistic models of structural response are obtained more easily and faster.
DEFF Research Database (Denmark)
Schmidt, Jesper Hvass; Brandt, Christian; Pedersen, Ellen Raben;
2014-01-01
Objective: To create a user-operated pure-tone audiometry method based on the method of maximum likelihood (MML) and the two-alternative forced-choice (2AFC) paradigm with high test-retest reliability without the need of an external operator and with minimal influence of subjects' fluctuating...
Directory of Open Access Journals (Sweden)
Yan-yang Wang
2014-01-01
Full Text Available The vibration of SRM obtains less attention for in-wheel motor applications according to the present research works. In this paper, the vertical component of SRM unbalanced radial force, which is named as SRM vertical force, is taken into account in suspension performance for in-wheel motor driven electric vehicles (IWM-EV. The analysis results suggest that SRM vertical force has a great effect on suspension performance. The direct cause for this phenomenon is that SRM vertical force is directly exerted on the wheel, which will result in great variation in tyre dynamic load and the tyre will easily jump off the ground. Furthermore, the frequency of SRM vertical force is broad which covers the suspension resonance frequencies. So it is easy to arouse suspension resonance and greatly damage suspension performance. Aiming at the new problem, FxLMS (filtered-X least mean square controller is proposed to improve suspension performance. The FxLMS controller is based on active suspension system which can generate the controllable force to suppress the vibration caused by SRM vertical force. The conclusion shows that it is effective to take advantage of active suspensions to reduce the effect of SRM vertical force on suspension performance.
Equivalent body-force model for magnetostrictive transduction in EMATs
Nagy, Peter B.; Ribichini, Remo
2015-03-01
Electromagnetic Acoustic Transducers (EMATs) are an attractive alternative to standard piezoelectric probes in those applications where couplant fluid cannot be used, i.e. high speed or high temperature testing, or when specific wave-modes have to be excited. When used on ferromagnetic samples, EMATs generate elastic waves through three different transduction mechanisms: the Lorentz force, the magnetization force and magnetostriction. The modeling of such phenomena has drawn the attention of several researchers, leading to different physical formalizations, especially for magnetostriction, being the most complex mechanism. This work presents a physics-based model for tangential bias field magnetostrictive EMATs employing surface tractions equivalent to the inertia body forces caused by magnetostrictive strains. This type of modeling had been previously used to validate a Finite Element model for normal bias field EMATs and here is extended to the tangential bias field configuration. Moreover, it is shown that the proposed model is equivalent to a recently developed method using the spatial convolution integral of body forces with Green's tensor to model elastic wave generation in a solid half-space.
Orum, Aslihan; Takatori, Kazumasa; Hori, Shigeo; Ikeda, Tomiko; Yoshimura, Masamichi; Tani, Toshihiko
2016-08-01
Rectangular platelike particles of La2Ti2O7, a layered perovskite, were synthesized in KCl, NaCl, and LiCl by the molten flux method. The formation mechanism of the equilibrium shape in these alkali chloride fluxes was discussed in terms of the surface and interfacial energies of crystallographic planes. The atomic force microscopy (AFM) observations revealed that the developed plane of the platelike particles is along the interlayers in the {110}-type layered crystal structure, and is considered to represent the lowest surface energy plane in which strong, periodic Ti–O bond chains terminate. Herein, for the first time, a growth mechanism for La2Ti2O7 particles is proposed and discussed. Triangular prism structures along the c-axis were observed on the developed planes of KCl-grown particles whereas no such structures were found on those of LiCl-grown ones. AFM measurements suggest that the prism facets are {210}-La2Ti2O7, which results in lower interfacial energy within KCl.
Atitoaie, Alexandru; Stoleriu, Laurentiu; Tanasa, Radu; Stancu, Alexandru; Enachescu, Cristian
2016-04-01
The scientific community is manifesting a high research interest on spin crossover compounds and their recently synthesized nanoparticles, due to their various appealing properties, such as the bistability between a diamagnetic low spin state and a paramagnetic high spin state (HS), inter-switchable by temperature or pressure changes, light irradiation or magnetic field. The utility of these compounds showing hysteresis covers a broad area of applications, from the development of more efficient designs of temperature and pressure sensors to automotive and aeronautic industries and even a new type of molecular actuators. We are proposing in this work a study regarding the kinetic effects and the distribution of reversible and irreversible components on the thermal hysteresis of spin crossover nanoparticulated systems. We are considering here tridimensional systems with different sizes and also systems of nanoparticles with a Gaussian size distribution. The correlations between the kinetics of the thermal hysteresis, the distributions of sizes and intermolecular interactions and the transition temperature distributions were established by using the FORC (First Order Reversal Curves) method using a Monte Carlo technique within an Ising-like system.
International Nuclear Information System (INIS)
Highlights: • We propose and develop the LMDI approach to factorize changes in electricity bill vulnerability. • Spanish vulnerability (1995–2011) markedly grew mainly by increasing gas dependence. • Fuel price increase and growing importance of electricity damage energy security. • Energy intensity advances & fuel diversification: insufficient to drive vulnerability. • Main recommendation: enhance internal energy market and common external EU strategy. - Abstract: High energy dependence on fossil raises vulnerability concerns about security of supply and energy cost. This research examines the impact of high dependence of imported fuels for power generation in Spain through the quantification and analysis of the driving forces behind the change in its electricity bill. Following logarithmic mean Divisia indexes approach, we present and perform a new method that enables a complete decomposition of changes in electricity vulnerability into contributions from several drivers. In fact, we identify five predefined factors behind the variations in vulnerability in Spain during the 1998–2011 period: fuel price, average heat rate, fuel dependence, degree of electricity importance and energy intensity. The application of this approach reveals a significant increase in Spanish vulnerability in the last two decades, promoted by increments in fuel price and importance of electricity over the primary energy consumption, but especially by increasing fuel dependence (particularly gas dependence). Therefore, findings mainly advocate for those strategies aimed at reducing Spanish energy dependence. Also those improving thermal efficiency and energy intensity are indicated
Method of mechanical holding of cantilever chip for tip-scan high-speed atomic force microscope
Energy Technology Data Exchange (ETDEWEB)
Fukuda, Shingo [Department of Physics, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa 920-1192 (Japan); Uchihashi, Takayuki; Ando, Toshio [Department of Physics, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa 920-1192 (Japan); Bio-AFM Frontier Research Center, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa 920-1192 (Japan); Core Research for Evolutional Science and Technology of the Japan Science and Technology Agency, 7 Goban-cho, Chiyoda-ku, Tokyo 102-0076 (Japan)
2015-06-15
In tip-scan atomic force microscopy (AFM) that scans a cantilever chip in the three dimensions, the chip body is held on the Z-scanner with a holder. However, this holding is not easy for high-speed (HS) AFM because the holder that should have a small mass has to be able to clamp the cantilever chip firmly without deteriorating the Z-scanner’s fast performance, and because repeated exchange of cantilever chips should not damage the Z-scanner. This is one of the reasons that tip-scan HS-AFM has not been established, despite its advantages over sample stage-scan HS-AFM. Here, we present a novel method of cantilever chip holding which meets all conditions required for tip-scan HS-AFM. The superior performance of this novel chip holding mechanism is demonstrated by imaging of the α{sub 3}β{sub 3} subcomplex of F{sub 1}-ATPase in dynamic action at ∼7 frames/s.
Yan, Yifei; Zhang, Lisong; Yan, Xiangzhen
2016-01-01
In this paper, a single-slope tunnel pipeline was analysed considering the effects of vertical earth pressure, horizontal soil pressure, inner pressure, thermal expansion force and pipeline-soil friction. The concept of stagnation point for the pipeline was proposed. Considering the deformation compatibility condition of the pipeline elbow, the push force of anchor blocks of a single-slope tunnel pipeline was derived based on an energy method. Then, the theoretical formula for this force is thus generated. Using the analytical equation, the push force of the anchor block of an X80 large-diameter pipeline from the West-East Gas Transmission Project was determined. Meanwhile, to verify the results of the analytical method, and the finite element method, four categories of finite element codes were introduced to calculate the push force, including CAESARII, ANSYS, AutoPIPE and ALGOR. The results show that the analytical results agree well with the numerical results, and the maximum relative error is only 4.1%. Therefore, the results obtained with the analytical method can satisfy engineering requirements.
Solomon, S. C.
1980-01-01
The measurability of changes in plate driving or resistive forces associated with plate boundary earthquakes by laser rangefinding or VLBI is considered with emphasis on those aspects of plate forces that can be characterized by such measurements. Topics covered include: (1) analytic solutions for two dimensional stress diffusion in a plate following earthquake faulting on a finite fault; (2) two dimensional finite-element solutions for the global state of stress at the Earth's surface for possible plate driving forces; and (3) finite-element solutions for three dimensional stress diffusion in a viscoelastic Earth following earthquake faulting.
Addor, N.; Rohrer, M.; Furrer, R.; Seibert, J.
2014-12-01
Climate model simulations can show large departures from observations. These biases are often subtracted and then forgotten, or post-processed for impact modeling using pragmatic methods that typically do not account for the origins of the biases. Yet, enhancing our understanding of the reasons behind these biases is essential for the improvement of climate models and for the design of more robust bias-correction techniques. We pursue these objectives by exploring the links between biases at different spatial scales. We quantify biases at the regional scale in an alpine area (Switzerland) and explore whether they are influenced by the misrepresentation of the frequency, temperature and precipitation of circulation types (CTs) at the synoptic scale. Our analysis relies on simulations from 14 regional climate models (RCMs) forced by general circulation models and produced for the ENSEMBLES project. For each model, we characterized the daily synoptic situation over 1960-2099 by using a CT classification based on a hierarchical cluster analysis of principal components. The classification relies on sea level pressure fields within an area representative of the European Alps. We find significant biases in the CT frequency for 1980-2001 and that some of them lead to biases in temperature and precipitation reported in RCM comparison studies. For instance, in winter, models overestimate both the frequency and precipitation intensity of westerly situations, which carry moist air from the Atlantic Ocean and are responsible for most of the rainfall. We propose this as a main driver for the generalized overestimation of precipitation in winter, which is one of the most concerning biases affecting simulations in our area, as it leads to unrealistic estimates of snow accumulation. A general consequence is that CT-based downscaling methods that do not account for biases in CT frequency will generate biased outputs. Overall, we show that decomposing RCM time series using CTs
Liang, Zhang; Yanqing, Hou; Jie, Wu
2016-06-01
The multi-antenna synchronized receiver (using a common clock) is widely applied in GNSS-based attitude determination (AD) or terrain deformations monitoring, and many other applications, since the high-accuracy single-differenced carrier phase can be used to improve the positioning or AD accuracy. Thus, the line bias (LB) parameter (fractional bias isolating) should be calibrated in the single-differenced phase equations. In the past decades, all researchers estimated the LB as a constant parameter in advance and compensated it in real time. However, the constant LB assumption is inappropriate in practical applications because of the physical length and permittivity changes of the cables, caused by the environmental temperature variation and the instability of receiver-self inner circuit transmitting delay. Considering the LB drift (or colored LB) in practical circumstances, this paper initiates a real-time estimator using auto regressive moving average-based (ARMA) prediction/whitening filter model or Moving average-based (MA) constant calibration model. In the ARMA-based filter model, four cases namely AR(1), ARMA(1, 1), AR(2) and ARMA(2, 1) are applied for the LB prediction. The real-time relative positioning model using the ARMA-based predicting LB is derived and it is theoretically proved that the positioning accuracy is better than the traditional double difference carrier phase (DDCP) model. The drifting LB is defined with a phase temperature changing rate integral function, which is a random walk process if the phase temperature changing rate is white noise, and is validated by the analysis of the AR model coefficient. The auto covariance function shows that the LB is indeed varying in time and estimating it as a constant is not safe, which is also demonstrated by the analysis on LB variation of each visible satellite during a zero and short baseline BDS/GPS experiment. Compared to the DDCP approach, in the zero-baseline experiment, the LB constant
Gusso, André; Burnham, Nancy A.
2016-09-01
It has long been recognized that stochastic surface roughness can considerably change the van der Waals (vdW) force between interacting surfaces and particles. However, few analytical expressions for the vdW force between rough surfaces have been presented in the literature. Because they have been derived using perturbative methods or the proximity force approximation the expressions are valid when the roughness correction is small and for a limited range of roughness parameters and surface separation. In this work, a nonperturbative approach, the effective density method (EDM) is proposed to circumvent some of these limitations. The method simplifies the calculations of the roughness correction based on pairwise summation (PWS), and allows us to derive simple expressions for the vdW force and energy between two semispaces covered with stochastic rough surfaces. Because the range of applicability of PWS and, therefore, of our results, are not known a priori, we compare the predictions based on the EDM with those based on the multilayer effective medium model, whose range of validity can be defined more properly and which is valid when the roughness correction is comparatively large. We conclude that the PWS can be used for roughness characterized by a correlation length of the order of its rms amplitude, when this amplitude is of the order of or smaller than a few nanometers, and only for typically insulating materials such as silicon dioxide, silicon nitride, diamond, and certain glasses, polymers and ceramics. The results are relevant for the correct modeling of systems where the vdW force can play a significant role such as micro and nanodevices, for the calculation of the tip-sample force in atomic force microscopy, and in problems involving adhesion.
Researching Sex Bias in the Classroom.
Donlan, Dan
This paper outlines five methods of research on sex bias in the classroom: one-time survey, one class/one treatment, two class/two treatment, one class/random assignment to treatment, and analysis of differentiated effect. It shows how each method could be used in attempting to measure the effect of a unit on Norma Klein's "Mom, the Wolfman and…
Omanovic-Miklicanin, Enisa; Valzacchi, Sandro; Simoneau, Catherine; Gilliland, Douglas; Rossi, Francois
2014-10-01
A complete characterization of the different physico-chemical properties of nanoparticles (NPs) is necessary for the evaluation of their impact on health and environment. Among these properties, the surface characterization of the nanomaterial is the least developed and in many cases limited to the measurement of surface composition and zetapotential. The biological surface adsorption index approach (BSAI) for characterization of surface adsorption properties of NPs has recently been introduced (Xia et al. Nat Nanotechnol 5:671-675, 2010; Xia et al. ACS Nano 5(11):9074-9081, 2011). The BSAI approach offers in principle the possibility to characterize the different interaction forces exerted between a NP's surface and an organic--and by extension biological--entity. The present work further develops the BSAI approach and optimizes a solid-phase microextraction gas chromatography-mass spectrometry (SPME/GC-MS) method which, as an outcome, gives a better-defined quantification of the adsorption properties on NPs. We investigated the various aspects of the SPME/GC-MS method, including kinetics of adsorption of probe compounds on SPME fiber, kinetic of adsorption of probe compounds on NP's surface, and optimization of NP's concentration. The optimized conditions were then tested on 33 probe compounds and on Au NPs (15 nm) and SiO2 NPs (50 nm). The procedure allowed the identification of three compounds adsorbed by silica NPs and nine compounds by Au NPs, with equilibrium times which varied between 30 min and 12 h. Adsorption coefficients of 4.66 ± 0.23 and 4.44 ± 0.26 were calculated for 1-methylnaphtalene and biphenyl, compared to literature values of 4.89 and 5.18, respectively. The results demonstrated that the detailed optimization of the SPME/GC-MS method under various conditions is a critical factor and a prerequisite to the application of the BSAI approach as a tool to characterize surface adsorption properties of NPs and therefore to draw any further
Omanovic-Miklicanin, Enisa; Valzacchi, Sandro; Simoneau, Catherine; Gilliland, Douglas; Rossi, Francois
2014-10-01
A complete characterization of the different physico-chemical properties of nanoparticles (NPs) is necessary for the evaluation of their impact on health and environment. Among these properties, the surface characterization of the nanomaterial is the least developed and in many cases limited to the measurement of surface composition and zetapotential. The biological surface adsorption index approach (BSAI) for characterization of surface adsorption properties of NPs has recently been introduced (Xia et al. Nat Nanotechnol 5:671-675, 2010; Xia et al. ACS Nano 5(11):9074-9081, 2011). The BSAI approach offers in principle the possibility to characterize the different interaction forces exerted between a NP's surface and an organic--and by extension biological--entity. The present work further develops the BSAI approach and optimizes a solid-phase microextraction gas chromatography-mass spectrometry (SPME/GC-MS) method which, as an outcome, gives a better-defined quantification of the adsorption properties on NPs. We investigated the various aspects of the SPME/GC-MS method, including kinetics of adsorption of probe compounds on SPME fiber, kinetic of adsorption of probe compounds on NP's surface, and optimization of NP's concentration. The optimized conditions were then tested on 33 probe compounds and on Au NPs (15 nm) and SiO2 NPs (50 nm). The procedure allowed the identification of three compounds adsorbed by silica NPs and nine compounds by Au NPs, with equilibrium times which varied between 30 min and 12 h. Adsorption coefficients of 4.66 ± 0.23 and 4.44 ± 0.26 were calculated for 1-methylnaphtalene and biphenyl, compared to literature values of 4.89 and 5.18, respectively. The results demonstrated that the detailed optimization of the SPME/GC-MS method under various conditions is a critical factor and a prerequisite to the application of the BSAI approach as a tool to characterize surface adsorption properties of NPs and therefore to draw any further
Directory of Open Access Journals (Sweden)
Gerhard Louw
2011-11-01
Full Text Available The utility of military force in general, and that of military forces in particular, has been the subject of much debate since the end of the Cold War in 1989. At the same time, as the threat and incidence of state-on-state war receded, along with its associated conventional force strategies, structures and doctrine, governments were increasingly calling upon their armed forces to carry out missions that they were not trained and equipped for. These tasks included peace support, state-building, humanitarian aid, counter-insurgency and counter-terrorism, all of which engendered a plethora of arguments pointing to a new paradigm of war. The Utility of Force, produced by General Sir Rupert Smith in 2005, is still one of the seminal works in this regard – and the ideas contained therein stand central to the arguments contained in Angstrom and Duyvesteyn’s book. Since the latter is concurrently a critique, an elaboration and a validation of Smith’s tome, one should preferably have read The Utility of Force before tackling Modern War. This is not essential, though: Modern War is perfectly able to stand on its own, especially since it targets those academics that would be conversant with its main themes anyway.
Directory of Open Access Journals (Sweden)
Yiyun Lu
2012-01-01
Full Text Available Magnetic forces of a cylinder shape bulk high-temperature superconductor (HTS over a permanent magnet guideway (PMG are studied mathematically. One cylindrical bulk HTS with a diameter of 30 mm and 15 mm in height is used. Two types of PMG are employed for external magnetic fields consideration. The relationship of magnetic forces of bulk HTS under different lateral offsets over PMG is studied with 3D-model finite element method (FEM. The calculation results show that the maximum magnetic levitation force of bulk HTS over PMG is tightly related to the applied magnetic field distribution. For the symmetrical PMG, the maximum magnetic levitation force decreases linearly with the increase of lateral offset of the bulk sample. For the Halbach PMG, when lateral offset changes from 0 mm to 25 mm, the maximum magnetic levitation force increases with the increase of lateral offset of the bulk HTS. When the lateral offset exceeds the center of the Halbach by 25 mm, the maximum levitation force decreases rapidly with the increase of the lateral offset of the bulk sample.
Publication Bias The "File-Drawer Problem" in Scientific Inference
Scargle, J D
1999-01-01
Publication bias arises whenever the probability that a study is published depends on the statistical significance of its results. This bias, often called the file-drawer effect since the unpublished results are imagined to be tucked away in researchers' file cabinets, is potentially a severe impediment to combining the statistical results of studies collected from the literature. With almost any reasonable quantitative model for publication bias, only a small number of studies lost in the file-drawer will produce a significant bias. This result contradicts the well known Fail Safe File Drawer (FSFD) method for setting limits on the potential harm of publication bias, widely used in social, medical and psychic research. This method incorrectly treats the file drawer as unbiased, and almost always misestimates the seriousness of publication bias. A large body of not only psychic research, but medical and social science studies, has mistakenly relied on this method to validate claimed discoveries. Statistical c...
Sensitivity of hydrologic simulations to bias corrected driving parameters
Papadimitriou, Lamprini; Grillakis, Manolis; Koutroulis, Aristeidis; Tsanis, Ioannis
2016-04-01
Climate model outputs feature systematic errors and biases that render them unsuitable for direct use by the impact models. To deal with this issue many bias correction techniques have been developed to adjust the modelled variables against observations. For the most common applications adjustment concerns only precipitation and temperature whilst for others all the driving parameters (including radiation, wind speed, humidity, air pressure) are bias adjusted. Bias adjusting only part of the variables required as biophysical model input could affect the physical consistency among input variables and is poorly studied. It is important to determine and quantify the effect that bias adjusting each climate variable has on the impact model's simulation and identify parameters that could be treated as raw outputs for specific model applications. In this work, the sensitivity of climate simulations to bias adjusted driving parameters is tested by conducting a series of model runs, for which the impact model JULES is forced with: i) not bias corrected input variables, ii) all bias corrected input variables, iii-viii) all input variables bias corrected except for: iii) precipitation, iv) temperature, v) radiation, vi) specific humidity, vii) air pressure and viii) wind speed. This set of runs is conducted for three climate models of different equilibrium climate sensitivity: GFDL-ESM2M, MIROC-ESM-CHEM and IPSL-CM5A-LR. The baseline for the comparison of the experimental runs is a JULES run forced with the WFDEI dataset, the dataset that was used as the observational dataset for adjusting biases. The comparative analysis is performed using the time period 1981-2010 and focusing on output variables of the hydrological cycle (runoff, evapotranspiration, soil moisture).
Assessing Bias in Search Engines.
Mowshowitz, Abbe; Kawaguchi, Akira
2002-01-01
Addresses the measurement of bias in search engines on the Web, defining bias as the balance and representation of items in a collection retrieved from a database for a set of queries. Assesses bias by measuring the deviation from the ideal of the distribution produced by a particular search engine. (Author/LRW)
Directory of Open Access Journals (Sweden)
Wei-Hsi Chen
2014-06-01
Full Text Available A reversed-phase high-performance liquid chromatography (HPLC and liquid chromatography-tandem mass spectrometry (LC-MS/MS method was applied to study the forced degradation behavior and stability of epidepride. 123I radioisotope-labeled epidepride, [(--N-{[(2S-1-ethylpyrrolidin-2-yl]methyl}-5-iodo-2,3- dimethoxybenzamide] is a radiotracer with a high affinity for dopamine D2 receptors in the brain and has been used as an imaging agent for single-photon emission computed tomography. HPLC studies were performed using 127I-epidepride (the nonradioactive compound, instead of 123I-epidepride, with an RP-18 column using a mobile phase consisting of methanol, acetonitrile, and ammonium acetate (pH 7.0, 10 mM. The eluent flow rate and the wavelength for HPLC detection were 0.5 mL/min and 210 nm, respectively. The ligand was exposed to acid (1 N HCl and alkaline (1 N NaOH media and was subjected to oxidative decomposition at room temperature using 3% H2O2 and to thermal decomposition at 50°C. After various reaction times (30 minutes, 1 hour, 2 hours, 8 hours, and 24 hours, the substances were investigated by HPLC and LC-MS/MS. Although no decomposition products were observed after the acidic, alkaline, and thermal treatments, >80% of the initial amount of 127I-epidepride was oxidized within 24 hours in the presence of H2O2. Only one major oxidation product with an m/z value of 435 was observed, in addition to the 127I-epidepride species (m/z 419. The product was characterized by LC-MS/MS fragmentation, and the deteriorated type and fragmentation pathways were proposed for epidepride.
Test Bias and the Elimination of Racism
Sedlacek, William E.
1977-01-01
Three types of test bias are discussed: content bias, atmosphere bias, and use bias. Use bias is considered the most important. Tests reflect the bias in society, and eliminating test bias means eliminating racism and sexism in society. A six-stage model to eliminate racism and sexism is presented. (Author)
Optimal design of APD biasing circuit
Institute of Scientific and Technical Information of China (English)
SUN Chun-sheng; QIN Shi-qiao; WANG Xing-shu; ZHU Dong-hua
2007-01-01
This paper proposes a control method for avalanche photodiode (APD) reverse bias with temperature compensation and load resistance compensation. The influence of background light and load resistance on APD detection circuit is analyzed in detail. A theoretical model of temperature compensation and load resistance compensation is established, which is used for APD biasing circuit designing. It is predicted that this control method is especially suitable for LD laser range finder used on vehicles. Experimental results confirm thatthe design proposed in this paper can considerablely improve the performance of range finder.
Institute of Scientific and Technical Information of China (English)
崔鹏; 夏禾; 夏超逸; 吴萱
2014-01-01
随着公路、铁路、城市立交桥的大量建设，跨线桥数量剧增，桥墩被汽车撞击的可能性大大增加。建立卡车撞击桥墩精细有限元分析模型，采用LS-DYNA碰撞分析软件计算分析了Ford卡车以不同速度撞击桥墩的撞击力特性。采用全局平均法、局部平均法、等效位移法、简化脉冲荷载法4种计算汽车撞击力等效静力方法，计算了撞击过程的等效静力值，并与美国《AASHTO》规范、中国《铁路桥涵设计基本规范》和《公路桥涵设计通用规范》中给出的汽车等效静力限值进行了比较，指出了各种计算方法的适应范围和精确度，可供工程设计参考。%Due to quick development of elevated overpass bridges of highways,railways and urban overpass nowadays,the probability of vehicle colliding with piers increases sharply.An analysis model for a truck-pier system was set up using the finite element software ANSYS LS_DYNA to analyze the impact force characteristics of the truck at different speeds.Here,four calculation methods for equivalent static force of truck-pier collision force were presented including the global average method,the local average method,the equivalent displacement method,and the simplified pulse load method.Using these methods,the equivalent static forces were calculated,and the results were compared with the allowances given in AASHTO-LRFD,Chinese Railway Code and Chinese Highway Code.Based on comparisons,the adaptive scope and the accuracy of the four methods were pointed out,a reference was provided for engineering design.
Third, J. R.; Chen, Y.; Müller, C. R.
2016-07-01
Lattice-Boltzmann method (LBM) simulations of a gas-fluidised bed have been performed. In contrast to the current state-of-the-art coupled computational fluid dynamics-discrete element method (CFD-DEM) simulations, the LBM does not require a closure relationship for the particle-fluid interaction force. Instead, the particle-fluid interaction can be calculated directly from the detailed flow profile around the particles. Here a comparison is performed between CFD-DEM and LBM simulations of a small fluidised bed. Simulations are performed for two different values of the superficial gas velocity and it is found that the LBM predicts a larger bed expansion for both flowrates. Furthermore the particle-fluid interaction force obtained for LBM simulations is compared to the force which would be predicted by a CFD-DEM model under the same conditions. On average the force predicted by the CFD-DEM closure relationship is found to be significantly smaller than the force obtained from the LBM.
Wijk, van der V.; Krut, S.; Pierrot, F.; Herder, J.L.
2011-01-01
This paper proposes a generic method for deriving the general shaking force balance conditions of parallel manipulators. Instead of considering the balancing of a parallel manipulator link-by-link or leg-by-leg, the architecture is considered altogether. The first step is to write the linear momentu
The k-ε-f_{P} model applied to double wind turbine wakes using different actuator disk force methods
DEFF Research Database (Denmark)
Laan, van der, Paul Maarten; Sørensen, Niels N.; Réthoré, Pierre-Elouan;
2015-01-01
The newly developed k-ε-fP eddy viscosity model is applied to double wind turbine wake configurations in a neutral atmospheric boundary layer, using a Reynolds-Averaged Navier–Stokes solver. The wind turbines are represented by actuator disks. A proposed variable actuator disk force method...... is employed to estimate the power production of the interacting wind turbines, and the results are compared with two existing methods: a method based on tabulated airfoil data and a method based on the axial induction from 1D momentum theory. The proposed method calculates the correct power, while the other...
Wang, Yinan; Kong, Feng; Huang, Lijie; Liu, Jia
2016-10-01
Self-esteem is a widely studied construct in psychology that is typically measured by the Rosenberg Self-Esteem Scale (RSES). However, a series of cross-sectional and longitudinal studies have suggested that a simple and widely used unidimensional factor model does not provide an adequate explanation of RSES responses due to method effects. To identify the neural correlates of the method effect, we sought to determine whether and how method effects were associated with the RSES and investigate the neural basis of these effects. Two hundred and eighty Chinese college students (130 males; mean age = 22.64 years) completed the RSES and underwent magnetic resonance imaging (MRI). Behaviorally, method effects were linked to both positively and negatively worded items in the RSES. Neurally, the right amygdala volume negatively correlated with the negative method factor, while the hippocampal volume positively correlated with the general self-esteem factor in the RSES. The neural dissociation between the general self-esteem factor and negative method factor suggests that there are different neural mechanisms underlying them. The amygdala is involved in modulating negative affectivity; therefore, the current study sheds light on the nature of method effects that are related to self-report with a mix of positively and negatively worded items.
Directory of Open Access Journals (Sweden)
Grković Vojin R.
2013-01-01
Full Text Available The paper presents the mathematical model and the procedure for calculation of the resultant force acting on the air cooled gas turbine blade(s based on the aerodynamic theory and computation of the circulation around the blade profile. In the conducted analysis was examined the influence of the cooling air mass flow expressed through the cooling air flow parameter λc, as well as, the values of the inlet and outlet angles β1 and β2, on the magnitude of the tangential and axial forces. The procedure and analysis were exemplified by the calculation of the tangential and axial forces magnitudes. [Projekat Ministarstva nauke Republike Srbije: Development and building the demonstrative facility for combined heat and power with gasification
International Nuclear Information System (INIS)
The blind prediction and post-test correlation analyses are conducted on the forced vibration tests of the 1/4 scale reinforced concrete cylindrical containment model both before and after backfill. In the present paper described for the case after backfill, the ring exciting thin layer technique was introduced to account realistically for the axisymmetrical irregularity of the soil condition due to the backfill. The computed results demonstrated that the proposed method has a great potential for simulating the dynamic responses of the soil-structure system to the forced vibration. (author). 5 refs., 8 figs
International Nuclear Information System (INIS)
In order to examine the applicability of the existing estimation equations of the impact force due to tsunami floating debris, the collision tests are carried out. In the experiments, logs and full-scale light car are used. In this report, two types of existing equations, one is based on the Young's module of the debris (Eq.A) and the other one is based on the stiffness of the debris (Eq.B), are focused on. The estimated impact forces using Eq.A with log's Young module obtained by the material test agree with measured forces obtained by the collision test. But Eq.A does not applicate to a car because it is not easy to determine the Young's module of a car. On the other hand, the estimated impact forces using Eq.B with car's stiffness obtained by the static loading test agree with measured forces obtained by the collision test. This indicates that Eq.B unable us to estimate impact force of the floating debris such as car if the stiffness of the debris is determined. (author)
Application and investigation of a bound for outcome reporting bias
Directory of Open Access Journals (Sweden)
Gamble Carrol
2007-03-01
Full Text Available Abstract Background Direct empirical evidence for the existence of outcome reporting bias is accumulating and this source of bias is recognised as a potential threat to the validity of meta-analysis of randomised clinical trials. Methods A method for calculating the maximum bias in a meta-analysis due to publication bias is adapted for the setting where within-study selective non-reporting of outcomes is suspected, and compared to the alternative approach of missing data imputation. The properties of both methods are investigated in realistic small sample situations. Results The results suggest that the adapted Copas and Jackson approach is the preferred method for reviewers to apply as an initial assessment of robustness to within-study selective non-reporting. Conclusion The Copas and Jackson approach is a useful method for systematic reviewers to apply to assess robustness to outcome reporting bias.
Directory of Open Access Journals (Sweden)
Junfeng Gu
2015-10-01
Full Text Available Binding affinity prediction of protein–ligand complexes has attracted widespread interest. In this study, a self-adaptive steered molecular dynamics (SMD method is proposed to reveal the binding affinity of protein–ligand complexes. The SMD method is executed through adjusting pulling direction to find an optimum trajectory of ligand dissociation, which is realized by minimizing the stretching force automatically. The SMD method is then used to simulate the dissociations of 19 common protein–ligand complexes which are derived from two homology families, and the binding free energy values are gained through experimental techniques. Results show that the proposed SMD method follows a different dissociation pathway with lower a rupture force and energy barrier when compared with the conventional SMD method, and further analysis indicates the rupture forces of the complexes in the same protein family correlate well with their binding free energy, which reveals the possibility of using the proposed SMD method to identify the active ligand.
Parametric study of statistical bias in laser Doppler velocimetry
International Nuclear Information System (INIS)
Analytical studies have often assumed that LDV velocity bias depends on turbulence intensity in conjunction with one or more characteristic time scales, such as the time between validated signals, the time between data samples, and the integral turbulence time-scale. These parameters are presently varied independently, in an effort to quantify the biasing effect. Neither of the post facto correction methods employed is entirely accurate. The mean velocity bias error is found to be nearly independent of data validation rate. 15 refs
Hersam, Mark C. (Inventor); Pingree, Liam S. C. (Inventor)
2008-01-01
A conductive atomic force microscopy (cAFM) technique which can concurrently monitor topography, charge transport, and electroluminescence with nanometer spatial resolution. This cAFM approach is particularly well suited for probing the electroluminescent response characteristics of operating organic light-emitting diodes (OLEDs) over short length scales.
Directory of Open Access Journals (Sweden)
Roya Shademani
2016-03-01
Full Text Available In this paper, water entry of wedges with deadrise angles ranging from 10 to 80 degrees at two different velocities is simulated. Impact forces, spray parameters, cavity formation above the chine, and secondary impact forces due to the cavity formation are investigated with particular focus on the extreme angles. To this end, a two dimensional two-phase Finite-Element based Finite-Volume (FEM-FVM code is developed and validated against experimental data with good compliance. Free surface modeling in this software is accomplished by applying Volume of Fluid (VOF method. In addition to the extraction of impact forces, secondary impact forces, spray characteristics, and cavity formation, it is demonstrated that there is a combined critical length and entry velocity where the spray formation stops and the spray vanishes. It is also shown that the cavity and secondary impact do not occur under these circumstances. Moreover, it is concluded that for these particular cases, there is a maximum secondary impact force that occurs for the deadrises angles less than 20o.