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Sample records for bianca hrsch gerald

  1. Understanding Infidelity: An Interview with Gerald Weeks

    Science.gov (United States)

    Smith, Travis

    2011-01-01

    In this interview, Gerald Weeks shares his expertise on the topic of infidelity and couples counseling. Dr. Weeks defines infidelity, presents assessment strategies for treating the issue of infidelity, and discusses an intersystemic model for infidelity treatment when counseling couples. Dr. Weeks also provides insight into common mistakes made…

  2. Obituary: Gerald S. Hawkins, 1928-2003

    Science.gov (United States)

    Krupp, Edwin C.

    2003-12-01

    Public perceptions of human prehistory were transformed in the 1960s by astronomer Gerald Stanley Hawkins, who died suddenly and unexpectedly of a heart attack on 26 May 2003 at Hawkridge Farm, in Virginia, near Washington, D.C. His astronomical analysis of Stonehenge, first published in "Nature" on 26 October 1963, and subsequently developed and framed with historical and cultural context in a best-selling book, "Stonehenge Decoded" (1965, in collaboration with John B. White), was also showcased internationally at the time in a one-hour CBS television documentary special, "The Mystery of Stonehenge". The high-profile, unconventional, and cross-disciplinary character of Hawkins's celestial interpretation of Stonehenge alignments and his configuration of the monument as an eclipse predictor attracted archaeological skepticism that provided the controversy desired by the makers of the television program. Antagonism was contrived between Hawkins and archaeologist Richard J.C. Atkinson by the production team to introduce conflict that would enhance audience interest in the subject, and the televised dispute troubled both men for decades. By the early 1970s, however, Hawkins had inspired others to examine the astronomical potential of ancient and prehistoric monuments in many parts of the world. He ignited modern studies of archaeoastronomy. In fact, in a second book on the subject, "Beyond Stonehenge" (1973), Hawkins reported his expanding perspective with accounts of his fieldwork on New Kingdom temples in Egypt, on the giant geoglyphs near Nazca, Peru, and at other sites. He also brought the work of other investigators to the attention of his many readers. He established methods and protocols for alignment studies and invited others to use them. Following, in a sense, the footsteps Sir J. Norman Lockyer left among the antiquities in the late nineteenth and early twentieth century, Hawkins reexamined the alignments of several Egyptian temples, documented significant

  3. Measurement of the Lorentz-FitzGerald body contraction

    Science.gov (United States)

    Rafelski, Johann

    2018-02-01

    A complete foundational discussion of acceleration in the context of Special Relativity (SR) is presented. Acceleration allows the measurement of a Lorentz-FitzGerald body contraction created. It is argued that in the back scattering of a probing laser beam from a relativistic flying electron cloud mirror generated by an ultra-intense laser pulse, a first measurement of a Lorentz-FitzGerald body contraction is feasible.

  4. Gerald: a general environment for radiation analysis and design

    International Nuclear Information System (INIS)

    Boyle, Ch.; Oliveira, P.I.E. de; Oliveira, C.R.E. de; Adams, M.L.; Galan, J.M.

    2005-01-01

    Full text of publication follows: This paper describes the status of the GERALD interactive workbench for the analysis of radiation transport problems. GERALD basically guides the user through the various steps that are necessary to solve a radiation transport problem, and is aimed at education, research and industry. The advantages of such workbench are many: quality assurance of problem setup, interaction of the user with problem solution, preservation of theory and legacy research codes, and rapid proto-typing and testing of new methods. The environment is of general applicability catering for analytical, deterministic and stochastic analysis of the radiation problem and is not tied to one specific solution method or code. However, GERALD is being developed as a portable, modular, open source framework which renders itself quite naturally to the coupling of existing computational tools through specifically developed plug-ins. By offering a common route for setting up, solving and analyzing radiation transport problems GERALD offers the possibility of methods intercomparison and validation. Such flexible radiation transport environment will also facilitate the coupling of radiation physics methods to other physical phenomena and their application to other areas of application such as medical physics and the environment. (authors)

  5. An Appreciation of Social Context: One Legacy of Gerald Salancik.

    Science.gov (United States)

    Weick, Karl E.

    1996-01-01

    Evaluates Gerald Salancik's work, tracing salient themes and focusing on his constant attention to the social context of individual and organizational motivation and action. Shows the centrality of social context in his studies on priming effects, commitment, power, resource dependence, justification, decision making, and other topics. He excelled…

  6. Obituary: Gerald Frederick Tape, 1915-2005

    Science.gov (United States)

    Hughes, Robert E.

    2007-12-01

    Gerald Frederick Tape, a distinguished science statesman and administrator, died on November 20, 2005. Jerry, as he was known to all, took on many diverse and important responsibilities throughout his life and dealt with them with quiet authority and grace. This was the hallmark of his life. The Board of Trustees of Associated Universities, Inc., which he served for many years, expressed this in its condolences, writing "Jerry personified integrity, thoroughness and dedication. His sensitivity for the views of others, his sincerity, his personal commitment, his calm approach and his unfailing good humor were all greatly admired and respected." Jerry was born in Ann Arbor, Michigan on May 29, 1915 but grew up in Milan, a nearby country farm community, and in Ypsilanti where his father was Principal of Michigan State Normal College, which later became Eastern Michigan University (EMU). It was there that he first became interested in physics. It was there also that he met and courted Josephine Waffen, who later would become his wife for more than sixty-six years and fill their lives with three loving sons, Walter, James, and Thomas. Upon graduation from EMU, Jerry was awarded a scholarship that took him to the University of Michigan where he earned a Ph.D. in Physics, researching the decay modes of the radioisotopes of iodine. In the Fall of 1939, during the waning days of the Great Depression, he was offered an Instructorship in the Physics Department of Cornell University, a promising start for a fruitful academic career. He brought his bride Jo to Ithaca and joined the cyclotron group under Robert Bacher and Willy Higginbotham while devising a laboratory course in nuclear techniques for graduate students. Bacher and Higginbotham soon left Cornell to join a new wartime laboratory at the Massachusetts Institute of Technology (MIT) and many other colleagues were "drafted" for war work. Bacher persuaded Jerry to join him at the MIT Radiation Laboratory in February

  7. Gerald McCann: The Rediscovery of a Fashion Designer

    OpenAIRE

    Almond, K; Riches, C

    2018-01-01

    The research for this article was initiated by the discovery of the archive of international fashion designer, Gerald McCann, hidden in a garage in Fleetwood, Lancashire, UK. The contents of the archive revealed a treasure trove of press cuttings photographs, fashion drawings and interviews as well as designs and costings from a once well-known designer, whose significance to the global fashion industry is sparsely documented and largely forgotten. This article reveals the history of the desi...

  8. The Girls’ Side. Analysis of Bianca Pitzorno’s Contribution to Children’s Literature

    Directory of Open Access Journals (Sweden)

    Elena Tosi

    2017-01-01

    Full Text Available This essay provides an overview of the contribution of the Italian writer Bianca Pitzorno to children’s literature. This author is important on both a national and international level. She dedicated her life to writing stories with female children and teenagers as lead characters when the literature of the mostly provided them with supporting roles with weak or submissive personalities. Other literary authors wrote about girls (e.g. Carroll, Michaelis, Lindgren, Dahl and Petrosino, but none of them ever embraced this task like Pitzorno. Also if we compare some of lead male characters in classic children’s literature (ones by Calvino, Collodi, De Amicis, Kipling and Malot with Pitzorno’s female ones, we can see that the latter are on par with their male counterparts.

  9. LA SAETA DEL TIEMPO: UNA LECTURA A GERALD WHITROW

    Directory of Open Access Journals (Sweden)

    M. BUTLER

    2011-12-01

    Full Text Available En la vida cotidiana, el mundo muestra una marcada diferencia entre el pasado y el futuro, pero —con una pequeña excepción— las leyes de la física son simétricas en el tiempo. Gerald Whitrow fue uno de los primeros en darse cuenta que la resolución de esta paradoja está de acuerdo con la cosmología y las condiciones iniciales en el nacimiento del universo. Pero esta simple conclusión oculta algunas profundas sutilezas que toman un nuevo giro con la aparición de la cosmología cuántica y la hipótesis del universo inflacionario. La cuestión aún no ha sido resuelta por completo, y sigue siendo uno de los grandes

  10. 77 FR 2605 - Public Notice for Waiver of Aeronautical Land-Use Assurance; Gerald R. Ford International Airport...

    Science.gov (United States)

    2012-01-18

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Public Notice for Waiver of Aeronautical Land-Use Assurance; Gerald R. Ford International Airport, Grand Rapids, MI AGENCY: Federal... this FAA action may be reviewed at this same location or at Gerald R. Ford International Airport, Grand...

  11. Gerald Caplan: A Tribute to the Originator of Mental Health Consultation

    Science.gov (United States)

    Erchul, William P.

    2009-01-01

    Gerald Caplan (1917-2008), world-renowned child and community psychiatrist, was the originator of the modern practice of mental health consultation. In addition to consultation, Caplan developed and refined many conceptual models and methods for practice for use in community mental health, psychology, and education. This tribute article focuses on…

  12. Cristallini e misurazioni biometriche nella Lepre bianca (Lepus timidus in Provincia di Sondrio

    Directory of Open Access Journals (Sweden)

    Maria Ferloni

    2003-10-01

    Full Text Available A partire dalla stagione venatoria 2000 è stato introdotto in Provincia di Sondrio il controllo di tutti i capi di Lepre bianca abbattuti, allo scopo di effettuare valutazioni accurate del sesso, dell'età e delle misurazioni biometriche degli animali. La valutazione dell'età è stata effettuata tramite pesatura del cristallino dell'occhio e tramite palpazione del tubercolo di Stroh. Per una valutazione dell'età è stata utilizzata come riferimento la curva dei pesi di Walhovd (1965. In totale, dal 2000 al 2002, sono stati analizzati 187 esemplari di Lepre bianca (84 maschi e 103 femmine. Dei 154 capi di cui è stata valutata l'età, 54 sono risultati piccoli dell'anno e 100 adulti, di cui 57 di 1 anno e 43 di oltre due anni. Il peso di cristallino rivelatosi discriminante per distinguere tra piccoli e adulti era compreso tra 220 e 240 mg, come rilevato anche da altri autori (Flux, 1970, Walhovd, 1965. È stata inoltre individuata una buona corrispondenza tra la valutazione dell'età tramite peso del cristallino e la palpazione del tubercolo di Stroh, tecnica che ha fornito una valutazione corretta della classe d'età nell'83% degli animali analizzati. Il peso del cristallino dei piccoli ha permesso anche di determinare approssimativamente la distribuzione delle nascite nel corso dell'anno. Le misurazioni biometriche rilevate sono state: lunghezza del corpo, lunghezza della coda, lunghezza dell'orecchio destro, lunghezza del piede posteriore, peso pieno e peso vuoto. I risultati ottenuti sono stati confrontati per le diverse classi di età e di sesso tramite Analisi della Varianza (One-Way ANOVA. Le differenze principali sono emerse tra giovani e adulti, relativamente al peso (sia peso pieno sia peso vuoto e, nel 2001, anche alla lunghezza totale, entrambi maggiori negli adulti. Tra gli adulti sono emerse differenze significative anche nel peso dei due sessi, con le femmine più pesanti dei maschi. Non sono invece state rilevate differenze

  13. Naturalizing Alterity: Edward Maturin’s Bianca: A Tale of Erin and Italy and Lady Morgan's Italy

    Directory of Open Access Journals (Sweden)

    Donatella Abbate Badin

    2011-08-01

    Full Text Available In the nineteenth century the image of Italy appealed also to Irish Romantic writers. But the way in which they naturalized the Italian alterity is quite ambivalent. On the one hand they filtered their images of the southern country through their relationship with England and thus ended up mirroring stereotypes common to the English-speaking world, and on the other hand they established a special, personal relationship with it shaped by their ideological and cultural differences from the British. This essay tackles the representations of Italy in two texts, namely Edward Maturin’s Bianca: A Tale of Erin and Italy, published in 1852, and in the earlier Italy (1821 by Lady Morgan. Both these works show that at that time there was a certain awareness, in Ireland, of the special historical and political conditions of Italy and of possible similarities with Ireland. Italy, oppressed by foreign domination yet aspiring to freedom, became a yardstick for gauging issues of subjugation, injustice, and national identity and invited sympathy from the citizens of a colonized country. Therefore, Italy was perceived as a mirror in which to reflect the Irish identity torn by aspirations which were hard to confess publicly or even to oneself. Keywords: Maturin, Lady Morgan, alterity, Italy, Irish Romanticism

  14. AESTHETICS OF OPPOSITION: THE POLITICS OF METAMORPHOSIS IN GERALD VIZENOR’S BEARHEART

    Directory of Open Access Journals (Sweden)

    Seyed Mohammad Marandi

    2014-09-01

    Full Text Available The Chippewa novelist Gerald Vizenor puts across his interconnected politico-philosophical notions of “survivance” and “terminal creeds” in his early novel, Bearheart. To do so, Vizenor implemented some of the aesthetic strategies of magical realism. He filled his novel with an excessive amount of bizarrely sexual and violent scenes—which turn out to be magical—in order to “upset” the established standards of normality. Moreover, he used American Indian mythic folktales of transformation and metamorphosis, a magical realist technique, to re-shape the cultural and tribal identity in Bearheart’s modernized context.

  15. Hawkins, Gerald

    Science.gov (United States)

    Murdin, P.

    2000-11-01

    British-born astronomer, professor at Boston University, claimed to have `decoded' Stonehenge. He found a pattern of alignments with 12 major lunar and solar events, finding a way to predict eclipses of the Moon, the summer and winter solstice, by use of the 56 Aubrey holes, the Heel Stone, and the four Station Stones. His work was supported by astronomer FRED HOYLE and savagely criticised by ar...

  16. 75 FR 68401 - Duncan Smith and Gerald Altizer-Continuance in Control Exemption-Eighteen Thirty Group, LLC and...

    Science.gov (United States)

    2010-11-05

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35436] Duncan Smith and..., LLC Duncan Smith and Gerald Altizer (collectively applicants), noncarrier individuals, have filed a... carriers. Mr. Smith owns 80% of Eighteen Thirty and 75% of Georges Creek. Mr. Altizer owns a 20% interest...

  17. Building genetic tools in Drosophila research: an interview with Gerald Rubin

    Directory of Open Access Journals (Sweden)

    2016-04-01

    Full Text Available Gerald (Gerry Rubin, pioneer in Drosophila genetics, is Founding Director of the HHMI-funded Janelia Research Campus. In this interview, Gerry recounts key events and collaborations that have shaped his unique approach to scientific exploration, decision-making, management and mentorship – an approach that forms the cornerstone of the model adopted at Janelia to tackle problems in interdisciplinary biomedical research. Gerry describes his remarkable journey from newcomer to internationally renowned leader in the fly field, highlighting his contributions to the tools and resources that have helped establish Drosophila as an important model in translational research. Describing himself as a ‘tool builder’, his current focus is on developing approaches for in-depth study of the fly nervous system, in order to understand key principles in neurobiology. Gerry was interviewed by Ross Cagan, Senior Editor of Disease Models & Mechanisms.

  18. Review: Gerald Beck (2013. Sichtbare Soziologie. Visualisierung und soziologische Wissenschaftskommunikation in der Zweiten Moderne

    Directory of Open Access Journals (Sweden)

    Axel Philipps

    2014-01-01

    Full Text Available Visualisierungen von Wissen hatten und haben im Kern des Faches Soziologie einen schweren Stand. Gerald BECK nimmt sich daher in seinem Buch "Sichtbare Soziologie" der Thematik an, um die Stellung von Visualisierungen in der Soziologie zu verstehen, damit verbundene Problemfelder zu identifizieren und für visuelle Umsetzungen zu sensibilisieren. Er setzt dazu beim Übergang zur Zweiten Moderne an und betrachtet anhand von neun Fallbeispielen gelungene und weniger gelungene Visualisierungen. Durch die verkürzte Aufarbeitung des Verhältnisses der Soziologie zum Bild bleiben jedoch wichtige Einsichten unberücksichtigt, sodass BECKs Empfehlungen, die Zahl der Visualisierungen und die visuelle Kompetenz zu erhöhen, kaum geeignet sind, die Skepsis in der Soziologie gegenüber Visualisierungen zu überwinden. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1401228

  19. Egg quality and blood parameters of “Bianca di Saluzzo” and Isa Brown hens kept under free range conditions

    Directory of Open Access Journals (Sweden)

    Luca Doglione

    2010-01-01

    Full Text Available Egg quality traits and some blood parameters of Bianca di Saluzzo hen (BSh were compared to Isa Brown hen (IBh. Birds were reared in free range conditions. Weightofthewholeegg Weight of the whole egg was higher (P≤0.01 for IBh, due to its higher amount of albumen (P≤0.01 whereas BSh egg showed the highest weight and relative percentage of yolk (PP≤0.01. IBh and BSh egg chemical composition was similar.Totalredcellsdidnotshowstatisticaldifferencesbetweengroups,whiletotalleucocytes Total red cells did not show statistical differences between groups, while total leucocytes were lower (P≤0.05 forBShhens. Heterophyl/Lymphocyte(H/L ratioof BShwaslower (P for BSh hens. Heterophyl/Lymphocyte(H/L ratioof BShwaslower (P . Heterophyl/Lymphocyte(H/L ratioof BShwaslower (P Heterophyl/Lymphocyte (H/L ratio of BSh was lower (P (PP≤0.01 than IBh(0.33 IBh (0.33 (0.33 vs. 0.82.IBh 0.82. IBh IBh α-1 acid glycoprotein (AGPmeanconcentrationswereaffectedbytime: (AGP mean concentrations were affected by time: the values registered after 15 d (T1 and 2 months (T2 of observation were similar (345±132 and 279±58 μg/mlrespectively,whileAGPvalueregisteredafter4months(T3weresignificantlyhigher μg/ml respectively,whileAGPvalueregisteredafter4months(T3weresignificantlyhigher , while AGP value registered after 4 months (T3 were significantly higher (700±487 μg/ml;BShdidnotdisplayanyAGPstatisticalvariationovertime.IBhalbuminmeancon- μg/ml; BShdidnotdisplayanyAGPstatisticalvariationovertime.IBhalbuminmeancon- BSh did not display any AGP statistical variation over time. IBh albumin mean con- centration (1.62 g/dL was statistically lower than BSh values (1.89 g/dL; in both groups no effect of time of sampling was recorded. Acutephaseprotein(APPvaluesofBShsuggestedamoreadaptive Acute phase protein (APPvaluesofBShsuggestedamoreadaptive (APP values of BSh suggested a more adaptive attitude to free range conditions and appeared more constant over time. The present

  20. Gerald J. Marks, M.D., FACS (1925-), founder of the Society of American Gastrointestinal Endoscopic Surgeons (SAGES).

    Science.gov (United States)

    Yeo, Theresa P; Cowan, Scott W; Yeo, Charles J

    2018-03-01

    This historical vignette describes the professional career of Gerald J. Marks, the founder of the Society of American Gastrointestinal and Endoscopic Surgeons and the International Federation of Societies of Endoscopic Surgeons. Dr. Marks is also the founding Associate Editor of Surgical Endoscopy, which celebrated its 30th anniversary in 2017. Dr. Marks is a renowned colorectal surgeon, an accomplished watercolor artist, and a fascinating personality.

  1. BIANCA, a biophysical model of cell survival and chromosome damage by protons, C-ions and He-ions at energies and doses used in hadrontherapy

    Science.gov (United States)

    Pietro Carante, Mario; Aimè, Chiara; Tello Cajiao, John James; Ballarini, Francesca

    2018-04-01

    An upgraded version of the BIANCA II biophysical model, which describes more realistically interphase chromosome organization and the link between chromosome aberrations and cell death, was applied to V79 and AG01522 cells exposed to protons, C-ions and He-ions over a wide LET interval (0.6–502 keV µm‑1), as well as proton-irradiated U87 cells. The model assumes that (i) ionizing radiation induces DNA ‘cluster lesions’ (CLs), where by definition each CL produces two independent chromosome fragments; (ii) fragment (distance-dependent) mis-rejoining, or un-rejoining, produces chromosome aberrations; (iii) some aberrations lead to cell death. The CL yield, which mainly depends on radiation quality but is also modulated by the target cell, is an adjustable parameter. The fragment un-rejoining probability, f, is the second, and last, parameter. The value of f, which is assumed to depend on the cell type but not on radiation quality, was taken from previous studies, and only the CL yield was adjusted in the present work. Good agreement between simulations and experimental data was obtained, suggesting that BIANCA II is suitable for calculating the biological effectiveness of hadrontherapy beams. For both V79 and AG01522 cells, the mean number of CLs per micrometer was found to increase with LET in a linear-quadratic fashion before the over-killing region, where a less rapid increase, with a tendency to saturation, was observed. Although the over-killing region deserves further investigation, the possibility of fitting the CL yields is an important feature for hadrontherapy, because it allows performing predictions also at LET values where experimental data are not available. Finally, an approach was proposed to predict the ion-response of the cell line(s) of interest from the ion-response of a reference cell line and the photon response of both. A pilot study on proton-irradiated AG01522 and U87 cells, taking V79 cells as a reference, showed encouraging

  2. Changes in physiological and some nutritional, nutraceuticals, chemical-physical, microbiological and sensory quality of minimally processed cactus pears cvs 'Bianca', 'Gialla' and 'Rossa' stored under passive modified atmosphere.

    Science.gov (United States)

    Palma, Amedeo; Continella, Alberto; La Malfa, Stefano; D'Aquino, Salvatore

    2018-03-01

    The objective of this study was to compare the overall quality changes of minimally processed cactus pears cvs 'Bianca', Gialla' and 'Rossa' stored at 4 °C for 10 days. Periodically in-package CO 2 , O 2 and C 2 H 4 were determined and fruit were assessed for overall quality changes (pH, acidity, sugars, phenolics, betacyanins and betaxanthines, antioxidant capacity, colour, firmness, microbiological population and sensory attributes). In a preliminary study three different polymeric films were tested to select the most suitable to design a package with a short lag time to achieve steady-state conditions. Results showed marked differences between measured in-package CO 2 and O 2 values and those calculated based on respiration of peeled fruit and film permeance to CO 2 and O 2 provided by manufactures. The sensory evaluation of packed fruit indicated in film BBT-Bolphane, which created a steady-state in-package partial pressure for CO 2 of 4.3-4.8 kPa and for O 2 of 4.8-5.5 kPa, as the best film. Results of in-package gas composition with the three cultivars were similar to those achieved in cv. 'Gialla' with the preliminary test. All measured qualitative parameters changed slightly over the storage period for all cultivars and followed the same trend, despite significant differences existing among cultivars. This study clearly showed a similar physiological behavior of minimally processed 'Bianca', 'Gialla' and 'Rossa' cactus pears. Storage conditions optimal for one cultivar fit well for the others; thus mixing fruit of different cultivars in a package designed for one specific cultivar does not lead to relevant deviation from expected results. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  3. Muuseum avastas haruldase pildi / Bianca Mikovitsh

    Index Scriptorium Estoniae

    Mikovitsh, Bianca

    2006-01-01

    Järvamaa muuseumi kunstikogu töödest: läti maalikunstniku Johann Hinrich Baumanni "Lamav jahimees koeraga", Andres Viidalepa "Härra peamees". Kommenteerivad teadur Helve Huttunen, peavarahoidja Külli Lupkin

  4. Inimesed tahavad aeglast internetti tagasi / Bianca Mikovitsh

    Index Scriptorium Estoniae

    Mikovitsh, Bianca

    2006-01-01

    Kiirema ja töökindlama WiMaxi internetiühenduse tulek tõrjub Järvamaalt välja senise odavama ja aeglasema WiFi lahenduse, millele inimesed on kulutanud juba tuhandeid kroone ja mida kohalikud omavalitsused siiani rahaliselt toetasid

  5. Gerald L. Epstein, PhD: director, center for science, technology, and security policy, American Association for the Advancement of Science (AAAS). Interview by Madeline Drexler.

    Science.gov (United States)

    Epstein, Gerald L

    2009-12-01

    Over his entire career, Gerald Epstein has toiled at the nexus of science, technology, and security. From 2003 to 2009, he was Senior Fellow for Science and Security at the Center for Strategic and International Studies Homeland Security Program, where he worked on reducing biological weapons threats, improving national preparedness, and easing potential tensions between the scientific research and national security communities. Epstein came to CSIS from the Institute for Defense Analyses. From 1996 to 2001, he served in the White House Office of Science and Technology Policy. And from 1983 to 1989, and again from 1991 until its demise in 1995, Epstein worked at the Congressional Office of Technology Assessment, where he directed a study on the proliferation of weapons of mass destruction, alongside research on other global security topics. A recognized expert in biological risk reduction, Epstein was actually trained as a physicist, having received SB degrees in physics and electrical engineering from MIT, and a PhD in physics from the University of California at Berkeley. How, then, did he come to study the evolving threat from bioterrorism? "What compelled me about bioterrorism was that it was a stellar example of a topic that would lead to a train wreck between the scientific community and the security community unless they figured out how to work together," he said. "The distance between a laboratory and a very large consequence event is a lot shorter in biology than in any other field. I got into bioterrorism to help make sure that the security community doesn't get so scared of the science that it shuts it down, and that the science community isn't so oblivious of security concerns that it pays no attention to them." Epstein spoke on November 6, 2009, with contributing writer Madeline Drexler, author of Emerging Epidemics: The Menace of New Infections (Penguin, 2009), an updated version of an earlier volume. Drexler holds a visiting appointment at the

  6. Gutscheine und Protektionismus / Gerald Braun

    Index Scriptorium Estoniae

    Braun, Gerald

    2016-01-01

    Euroopa Kohtu otsusest, mis käsitleb küsimust, millistel tingimustel võivad tööandjad väljastada oma töötajatele maksusoodustusega talonge, mida saab kasutada majutuseks, meelelahutuseks ja/või toitlustuseks (C‑179/14). Vt. ka lk. 439-440

  7. Gerald M. Edelman y su antropología neurológica. Presentación y discusión de su teoría de la mente

    Directory of Open Access Journals (Sweden)

    Javier Monserrat

    2016-10-01

    Full Text Available La pregunta esencial de la antropología (cuál es el origen y naturaleza del ser humano no puede hoy responderse sin la aportación de la neurología: de ahí que hablemos de antropología neurológica. Gerald Edelman ha sido en los últimos años un autor de referencia incuestionable, cuya aportación es presentada y discutida en el presente artículo. Primero su marco epistemológico. Después su darwinismo neural, desde cuya perpectiva se defiende la lógica selectiva de la evolución biológica frente a la lógica instruccional de la computación, bien serial o conexionista. La emergencia evolutiva de la memoria (el remembered present es la base para explicar la formación de la conciencia primaria, de la de orden superior y de la mente. Por último, abordamos la presentación de la teoría del núcleo dinámico y su explicación de la fenomenología de la conciencia. La discusión de la teoría de Edelman considera algunos aspectos y lagunas de la historia evolutiva, así como también la insuficiencia argumentativa sobre la especificación del psiquismo animal y las causas de la emergencia de la razón.

  8. Rodstvennik Monõ Lizõ / Bianca Kantino

    Index Scriptorium Estoniae

    Kantino, Bianca

    2004-01-01

    Uurijad on kindlaks teinud Leonardo da Vinci maalil "Gioconda" poseerinud naise isiku, kelleks oli Francesco del Gioconda naine Mona Lisa (1479-1528) ja leidnud naise otsese järeltulija - 51 aastase arhitekti

  9. Asteroseismology of δ Scuti and γ Doradus Stars Gerald Handler

    Indian Academy of Sciences (India)

    led to the observational detection and identification of a sufficient number ... satellite missions, theoretical advances on mode identification methods, ... The observational borders of the two pulsational instability strips (Rodriguez & Breger 2001; Handler & Shobbrook. 2002), with the thicker lines corresponding to the γ ...

  10. Nad ikka said selle Kärdla vana elektrijaama tööle / Bianca Mikovitš

    Index Scriptorium Estoniae

    Mikovitš, Bianca

    2009-01-01

    Siret Paju lavastusest "Ei teki ega kao" Kärdla elektrijaamas. Näidendi autorid Kerli Adov, Jaan Aps, Liis Lukk, Hiri Müüripeal, Siim Nurklik ja Kaur Riismaa. Projekti käivitas MTÜ Arhipelaag eesotsas Ere Naadiga

  11. Tähelepanu! Valmis olla! Jääme vanaks... / Luule Sakkeus ; kommenteerinud Bianca Mikovitš

    Index Scriptorium Estoniae

    Sakkeus, Luule, 1956-

    2015-01-01

    Eestis algab kolmas SHARE uuring (Survey of Health, Ageing and Retirement in Europe), mille käigus saadakse ülevaade 50-aastaste ja vanemate elanike tervislikust seisundist ja toimetulekust. Intervjuu TLÜ Eesti demograafia instituudi direktori ja Eesti 50+ elanikkonna eluoluküsitluse teaduskoordinaatori Luule Sakkeusega eakate olukorrast Eestis

  12. CVN 78 Gerald R. Ford Class Nuclear Aircraft Carrier (CVN 78)

    Science.gov (United States)

    2015-12-01

    Combat Systems Trial Rehearsal ( CSTR ) Jul 2014 Jul 2015 Jan 2016 May 20161 (Ch-2) Initial Operational Capability (IOC) Sep 2015 Sep 2016 Mar 2017 Oct...with the shipboard testing and integration schedule. (Ch-2) The current estimate for CSTR is rescheduled from November 2015 to May 2016 to reflect...resulting from the delay to delivery. Acronyms and Abbreviations CSTR - Combat Systems Trial Rehersal DT - Developmental Testing IOT&E - Initial Operational

  13. From nuclei to stars Festschrift in Honor of Gerald E. Brown

    CERN Document Server

    2011-01-01

    In one way or another, Gerry Brown has been concerned with questions about the universe, about its vast expanse as well as about its most miniscule fundamental constituents of matter throughout his entire life. In his endeavours to understand the universe in many manifestations from nuclei all the way to the stars, he has been influenced by some of the most prominent physicists of the 20th century, and he himself, in turn, has influenced a great many scholars. This volume, a collection of articles dedicated to Gerry on his 85th birthday, contains discussions of many of the issues which have at

  14. A Review of Gerald Caplan's "Theory and Practice of Mental Health Consultation."

    Science.gov (United States)

    Mendoza, Danielle W.

    1993-01-01

    Reviews Caplan's "Theory and Practice of Mental Health Consultation" (1970), considered classic seminal work in field of consultation. Presents Caplan's general definition of consultation and general principles or procedures of consultation. Describes each of Caplan's four models of consultation and compares models in terms of professional role of…

  15. The development of a spiritual wellness framework for the work context / Francois Gerald Watson

    OpenAIRE

    Watson, Francois Gerald

    2007-01-01

    Today's organisations are faced with changes such as increased competition and technological changes, not to mention the impact of globalisation on South African organisations. In a sense, the 21" century brought forth a more positive outlook and is described by some as the century of fortegenic living and wellness. Organisations today are searching for programmes that support strengths and wellness, as opposed to the historic employee assistance programmes. Spiritual wellness ...

  16. Chancen ungenutzt : Deutche bei Investionen noch zurückhaltend / Gerald Wolf

    Index Scriptorium Estoniae

    Wolf, Gerald

    2003-01-01

    Saksamaa ja Eesti majanduskoostööst, saksa investorite tegevusest Eestis ning Eesti EL-iga liitumise võimalikest mõjudest Saksa otseinvesteeringutele Eestisse. Tabel: valik Eesti majandusnäitajaid 2002-2003

  17. Digitale Wirtschaft – analoges Recht: Braucht das BGB ein Update? / Gerald Spindler

    Index Scriptorium Estoniae

    Spindler, Gerald

    2016-01-01

    Küsimusest, kas digitaalsete majandussuhete laienemise tingimustes oń vaja täiendada Saksamaa tsiviilseadustikku. Digitaalse sisu üleandmise lepingute teatavatest aspektidest, andmekaitsest, alaealiste kaitsest, müügilepingutest, üürilepingutest. Veebiplatvormide kasvavast tähtsusest digitaalmajanduses

  18. Briti kindral peab Kaitseliidu tulevikuks missioone võõrsil / Gerald Grosvenor ; interv. Peeter Kuimet

    Index Scriptorium Estoniae

    Grosvenor, Gerald

    2006-01-01

    Briti kaitsejõudude ülema asetäitja reservide alal räägib Suurbritannia Territoriaalarmeest, Kaitseliidu-sarnaste vabatahtlike organisatsioonide kasutamisest välismissioonidel, ajateenistusest ja olukorrast Iraagis

  19. Gerald Raunig, Gene Ray e Ulf Wuggenig (orgs. (2011, Critique of Creativity: Precarity, Subjectivity and Resistance in the Creative Industries

    Directory of Open Access Journals (Sweden)

    Pedro Quintela

    2013-09-01

    Full Text Available O debate sobre as indústrias culturais e criativas ganhou visibilidade nos últimos anos, ultrapassando o contexto académico e invadindo o espaço público, através dos média e dos agentes políticos. No contexto europeu a “agenda da criatividade” constitui hoje uma das principais tendências estruturadoras dos discursos e das práticas políticas. A obra Critique of Creativity, recentemente publicada, insere‑se nesta discussão. Este livro pretende contribuir para a análise do recente hype em torno...

  20. EUHOFA juhid valmistuvad juubelikongressiks / Filiep Defraye, Gerald Lipman, Sören Kühlwein Kristiansen, Sonja Saelaert ; intervjueerinud Gea Kammer

    Index Scriptorium Estoniae

    2011-01-01

    Õhtusöögivestlusest 14. mail Pärnus rahvusvahelise turismikoolide ühenduse juhtliikmetega, kes külastasid 13.-15. mail Eestit, et kooskõlastada organisatsiooni sügisel Tallinnas ja Pärnus toimuva kongressi, mille juhtmõte on Wel-being and Quality of life through Hospitality Education, programm ning tutvuda sihtkohtadega

  1. Fernando Pessoa and Aleister Crowley: new discoveries and a new analysis of the documents in the Gerald Yorke Collection

    NARCIS (Netherlands)

    Pasi, M.; Ferrari, P.

    2012-01-01

    The documents concerning the relationship between Fernando Pessoa and Aleister Crowley preserved in the Yorke Collection at the Warburg Institute (London) have been known for some time. However, recent new findings have prompted a new analysis of the dossier. The purpose of this article is to have a

  2. National airspace system : FAA reauthorization issues are critical to system transformation and operations statement of Gerald L. Dillingham, Ph.D.

    Science.gov (United States)

    2009-02-01

    As requested, this statement discusses issues for the reauthorization of the Federal Aviation Administration (FAA). The aviation industry is in a period of economic turmoil and faces an : uncertain future. At the same time, FAA is undertaking one of ...

  3. Transportation security : post-September 11th initiatives and long-term challenges : statement of Gerald L. Dillingham, Director, Physical Infrastructure Issues

    Science.gov (United States)

    2003-04-01

    This testimony responds to the request of the National Commission on Terrorist Attacks Upon the United States for information on GAO's work in transportation security. It addresses (1) transportation security before September 2001; (2) what the feder...

  4. Kapteni roll tõendite kogumisel / North East Branch of the Nautical Institute ; [tlk. Uno Laur ; toim. Viiu Suurväli ; eess.: Gerald Darling

    Index Scriptorium Estoniae

    1997-01-01

    Kapteni osa, logiraamatud ; lasti kahjustus, kaotus ja puudujääk ; kindlustus ja laevarike ; vaegtäitmise- ja ülekulupretensioonid ; ohtlikud sadamad ja laadimispaigad ; statsionaarsete ja ujuvobjektide vigastused ; õlireostus ; üldavarii ; päästmine ; laevakokkupõrked ; töötülide lahendamine ja distsiplinaarküsimused ; õnnetusjuhtumid inimestega ; piletita reisijad , põgenikud

  5. Kapteni roll tõendite kogumisel / North East Branch of the Nautical Institute ; [tlk. Uno Laur ; toim. Viiu Suurväli ; eess.: Gerald Darling

    Index Scriptorium Estoniae

    1998-01-01

    Kapteni osa, logiraamatud ; lasti kahjustus, kaotus ja puudujääk ; kindlustus ja laevarike ; vaegtäitmise- ja ülekulupretensioonid ; ohtlikud sadamad ja laadimispaigad ; statsionaarsete ja ujuvobjektide vigastused ; õlireostus ; üldavarii ; päästmine ; laevakokkupõrked ; töötülide lahendamine ja distsiplinaarküsimused ; õnnetusjuhtumid inimestega ; piletita reisijad , põgenikud

  6. The transport of drug in fibrosis. Comment on "Towards a unified approach in the modeling of fibrosis: A review with research perspectives" by Martine Ben Amar and Carlo Bianca

    Science.gov (United States)

    Ivancevic, Vladimir

    2016-07-01

    The topic of the review article [1] is the derivation of a multiscale paradigm for the modeling of fibrosis. Firstly, the biological process of the physiological and pathological fibrosis including therapeutical actions is reviewed. Fibrosis can be a consequence of tissue damage, infections and autoimmune diseases, foreign material, tumors. Some questions regarding the pathogenesis, progression and possible regression of fibrosis are lacking. At each scale of observation, different theoretical tools coming from computational, mathematical and physical biology have been proposed. However a complete framework that takes into account the different mechanisms occurring at different scales is still missing. Therefore with the main aim to define a multiscale approach for the modeling of fibrosis, the authors of [1] have presented different top-down and bottom-up approaches that have been developed in the literature. Specifically, their description refers to models for fibrosis diseases based on ordinary and partial differential equation, agents [2], thermostatted kinetic theory [3-5], coarse-grained structures [6-8] and constitutive laws for fibrous collagen networks [9]. A critical analysis has been addressed for all frameworks discussed in the paper. Open problems and future research directions referring to both biological and modeling insight of fibrosis are presented. The paper concludes with the ambitious aim of a multiscale model.

  7. Control and optimization in the modeling of fibrosis. Comment on "Towards a unified approach in the modeling of fibrosis: A review with research perspectives" by Martine Ben Amar and Carlo Bianca

    Science.gov (United States)

    Sivasundaram, Seenith

    2016-07-01

    The review paper [1] is devoted to the survey of different structures that have been developed for the modeling and analysis of various types of fibrosis. Biomathematics, bioinformatics, biomechanics and biophysics modeling have been treated by means of a brief description of the different models developed. The review is impressive and clearly written, addressed to a reader interested not only in the theoretical modeling but also in the biological description. The models have been described without recurring to technical statements or mathematical equations thus allowing the non-specialist reader to understand what framework is more suitable at a certain observation scale. The review [1] concludes with the possibility to develop a multiscale approach considering also the definition of a therapeutical strategy for pathological fibrosis. In particular the control and optimization of therapeutics action is an important issue and this article aims at commenting on this topic.

  8. IBICT: Brazilian experience in open access to service of Latin America

    Directory of Open Access Journals (Sweden)

    Editores Biblios

    2012-09-01

    Full Text Available Interview with Bianca Amaro de Melo, Coordinator of the Laboratory of Methodologies for Treatment and Dissemination of Information of the Brazilian Institute of Information in Science and Technology - IBICT.

  9. IBICT: Brazilian experience in open access to service of Latin America

    OpenAIRE

    Editores Biblios

    2012-01-01

    Interview with Bianca Amaro de Melo, Coordinator of the Laboratory of Methodologies for Treatment and Dissemination of Information of the Brazilian Institute of Information in Science and Technology - IBICT.

  10. Scott Richard Lyons, X-marks: Native Signatures of Assent. , Steve Russell, Sequoyah Rising: Problems in Post-Colonial Tribal Governance. , Sean Kicummah Teuton, Red Land, Red Power: Grounding Knowledge in the American Indian Novel. , Gerald Vizenor, Native Liberty: Natural Reason and Cultural Survivance.

    Directory of Open Access Journals (Sweden)

    James Mackay

    2011-09-01

    Full Text Available That American Indian nations have survived into the 21st century should be an occasion for celebration, given how truly close Native America came to a total obliteration. A combination of disease, vicious colonial warfare and the use of education as a weapon to “kill the Indian, save the man” had by the beginning of the 19th century reduced the number of people in the United States willing to claim Native ancestry in the census to just 250,000. (There were, of course, many more, but Indian bl...

  11. 77 FR 26759 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-05-07

    ... May 29, 2012. A. Federal Reserve Bank of Richmond (Adam M. Drimer, Assistant Vice President) 701 East Byrd Street, Richmond, Virginia 23261-4528: 1. Gerald F. Smith, Jr. Revocable Trust, (trustee, Gerald F. Smith, Jr.) Winchester, Virginia, to individually acquire voting shares of First National Corporation...

  12. Military Housing Privatization Initiative (MHPI), Eglin AFB, Florida and Hurlburt Field, Florida. Final Environmental Impact Statement

    Science.gov (United States)

    2011-05-01

    Gene G. Sanderson George E. Cox Gerald A. Rush* Gerald Goodson Ginny Graybiel Glenda L. Glover Gordon Eldridge Gordon Goodin Greg Artabasy Greg... Fanc ~np. Thank you very much. COLONEL CUMBIE: Thank you, sir. !Vlr. Robert Larson . MR. LARSON: My name is Robert Larson . The Military Housing

  13. Is Current US Counterinsurgency Doctrine Applicable to Lebanese Hizballah and the Taliban?

    Science.gov (United States)

    2010-06-11

    Taliban, What We’ve Heard, US Embassy Islamabad, 26 January 1995. 140Gerald Bourke , “Kabul Rivals Join Forces as Taliban Strikes Hard” Guardian 27...Report on Middle East Affairs 28, no. 6 (2009):35-36. Magazines/Journals Bourke , Gerald. “Kabul Rivals Join Forces as Taliban Strikes Hard.” Guardian

  14. Narrativ vejledning i skolen

    DEFF Research Database (Denmark)

    Plant, Peter

    2009-01-01

    Anmeldelse af John M. Winslade og Gerald D. Monk (2008). Narrativ vejledning i skolen. Virum: Dansk Psykologisk Forlag   Udgivelsesdato: FEB......Anmeldelse af John M. Winslade og Gerald D. Monk (2008). Narrativ vejledning i skolen. Virum: Dansk Psykologisk Forlag   Udgivelsesdato: FEB...

  15. the female role in the rebirth of italian nationalism in gabriele d ...

    African Journals Online (AJOL)

    User

    its past position of power in Europe, looking to the Roman Empire as ..... three sisters (similarly to Anna and Bianca Maria in La città morta as pointed out by Meda) .... studies and Venturi points to a direct connection between the garden.

  16. Tundeline itaalia bestseller / Udo Uibo

    Index Scriptorium Estoniae

    Uibo, Udo, 1956-

    2010-01-01

    32-aastase Alessandro d'Avenia debüütromaanist "Valge kui piim, punane kui veri" (Bianca come il latte, rossa come il sangue), mis avaldati tänavu jaanuaris, on saanud Itaalia selle aasta üks menukamaid raamatuid

  17. Population Dynamics and Diversity of Synechococcus on the New England Shelf

    Science.gov (United States)

    2014-09-01

    Suzanne L Strom, Brian Palenik, and Bianca Brahamsha. Vari- ability in protist grazing and growth on different marine Synechococcus isolates. Applied...Ricardo Anadón. Protist control of phytoplankton growth in the subtropical north-east atlantic. Marine Ecology Progress Series, 221:29– 38, 2001. [86

  18. BENTHIC SPECIES and Other Data from GILLISS and Other Platforms from 19760614 to 19760902 (NODC Accession 7700456)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data submitted by Dr. Gerald L. Engel. The data was collected between June 1976 and September 1976. This study was organized to collect Histopathology and Benthic...

  19. Aviation Safety: FAA Oversight of Aviation Repair Stations

    Science.gov (United States)

    1998-05-07

    Testimony of Gerald L. Dillingham, Associate Director, Transportation Issues, : Resources, Community, and Economic Development Division before the Subcommittee : on Aviation, Committee on Commerce, Science, and Transportation, U.S. Senate on : the Fe...

  20. Cellular computing

    National Research Council Canada - National Science Library

    Amos, Martyn

    2004-01-01

    ... 120 Ron Weiss, Thomas F. Knight Jr., and Gerald Sussman 8 The Biology of Integration of Cells into Microscale and Nanoscale Systems 148 Michael L. Simpson, Timothy E. McKnight, Michael A. Guillor...

  1. Raamaturappija / Karl Martin Sinijärv

    Index Scriptorium Estoniae

    Sinijärv, Karl Martin, 1971-

    1997-01-01

    Wolf, Christa. Medeia : hääled; Sermat, Toomas. Blaak ja Biduun; Liksom, Rosa. Ühe öö ekstaas; Durrell, Gerald. Bafuti hagijad; Saarinen, Esa. Filosoofia ajalugu tipult tipule Sokratesest Marxini

  2. cost-benefit analysis of anti-retroviral therapy (art) for hiv/aids

    African Journals Online (AJOL)

    user

    HIV/AIDS is high and that is why most patients cannot access HIV/AIDS treatment even though these drugs are supposed to .... Laboratory in New Mexico, Dr. Gerald Myers, and ... tuberculosis, and vaccinations against smallpox represented ...

  3. THE BIOCIDE TRIBUTYLTIN ALTERS TESTOSTERONE ESTERIFICATION IN MUD SNAILS (ILYANASSA OBSOLETA)

    Science.gov (United States)

    The Biocide Tributyltin Alters Testosterone Esterification in Mud Snails (Ilyanassa obsoleta)Meredith P. Gooding and Gerald A. LeBlanc Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695-7633Tributyltin (TBT...

  4. Protect Your Heart in the Heat

    Science.gov (United States)

    ... Aortic Aneurysm More Protect Your Heart in the Heat Updated:Jul 5,2017 Whatever brings you outside — ... might need to take special precautions in the heat, according to Gerald Fletcher, M.D., professor of ...

  5. Putting Science FIRST: Memories of Family Science Experiences.

    Science.gov (United States)

    Science and Children, 1996

    1996-01-01

    Presents anecdotes from prominent citizens including Bill Clinton, Alan Alda, Carl Sagan, Gerald Wheeler, JoAnne Vasquez, and Lynn Margulis in which they reminisce about interesting science experiences with their families. (JRH)

  6. "Pähklipureja" Uzide ja gaasimaskidega

    Index Scriptorium Estoniae

    2002-01-01

    Inglise rahvusballetis tuli lavale Pjotr Tsaikovski balleti "Pähklipureja" radikaalne versioon, kostüümide autor on karikaturist Gerald Scarfe, koreograaf Christopher Hampson, tantsivad ka Toomas Edur ja Age Oks

  7. Why Don't We Tell Children the Truth about America?

    Science.gov (United States)

    Marshall, Kim

    1980-01-01

    Frances FitzGerald's critique of American social studies and history curricula in "America Revised" is reviewed. The conclusion drawn is that censorship, special interests, and marketability exercise too great an influence on the textbook industry. (JMF)

  8. 75 FR 38184 - Proposed Collection; Comment Request for Regulation Project

    Science.gov (United States)

    2010-07-01

    ...-8 provides final income, estate and gift, and employment tax regulations relating to elections made..., and purchase of services to provide information. Approved: June 23, 2010. Gerald J. Shields, IRS...

  9. BENTHIC SPECIES and Other Data from GILLISS and Other Platforms from 19751027 to 19760827 (NODC Accession 7700455)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data was submitted by Dr. Gerald L. Engel. This study was organized to collect data on Parasite Type and Location. Parasite (both ecto- and endo-), and site of...

  10. Textbook of pharmacoepidemiology

    National Research Council Canada - National Science Library

    Strom, Brian L; Kimmel, Stephen E

    2006-01-01

    ... Pharmacovigilance Reporting Systems, 101 Gerald J. Dal Pan, Marie Lindquist, and Kate Gelperin 8 Overview of Automated Databases in Pharmacoepidemiology, 118 Brian L. Strom 9 Examples of Existing Automated ...

  11. From Calculus to Wavelets: ANew Mathematical Technique

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 4. From Calculus to Wavelets: A New Mathematical Technique Wavelet Analysis Physical Properties. Gerald B Folland. General Article Volume 2 Issue 4 April 1997 pp 25-37 ...

  12. Aviation Safety and Security: Challenges to Implementing the Recommendations of the White House Commission on Aviation Safety and Security -- GAO/T-RCED-97-90

    Science.gov (United States)

    1997-03-05

    This statement before Congress by Gerald L. Dillingham, Associate Director, : Transportation Issues, Resources, Community, and Economic Development Division, : General Accounting Office (GAO) assesses the recommendations contained in the : recently r...

  13. 75 FR 57287 - Notice of Intent to Repatriate a Cultural Item: Oshkosh Public Museum, Oshkosh, WI

    Science.gov (United States)

    2010-09-20

    ..., after Dennis Lee, son of Gerald Lee, donated the bowl to the museum. The Wisconsin State site report... placed with or near individual human remains at the time of death or later as part of the death rite or...

  14. Report on Follow-up Visit to Ecuador, Part 1

    National Research Council Canada - National Science Library

    Combs, Gerald F

    1961-01-01

    ...), National Institutes of Health, who visited Ecuador from January 15th to the 21st, 1961. Dr. Gerald F. Combs, PhD, visited Ecuador to discuss the nutritional survey conducted by ICNND in the summer of 1959...

  15. WATER TEMPERATURE and Other Data from DRIFTING BUOY From World-Wide Distribution from 19910101 to 19910331 (NODC Accession 9100101)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Drifting Buoy Data from the Canadian Data Center, submitted by Mr. Gerald P Lesblam, Marine Environmental Data Service (MEDS) Ottawa, Ontario, Canada in GF-3 format...

  16. International business theory and marketing theory

    OpenAIRE

    Soldner, Helmut

    1984-01-01

    International business theory and marketing theory : elements for internat. marketing theory building. - In: Marketing aspects of international business / Gerald M. Hampton ... (eds.). - Boston u.a. : Kluwer, 1984. - S. 25-57

  17. Raamaturida / Arno Oja

    Index Scriptorium Estoniae

    Oja, Arno, 1950-

    1995-01-01

    Wells, Herbert George. Lühike maailmaajalugu; Seton, Anya. Katherine, 1.osa; Durrell, Gerald. Linnud, loomad ja sugulased. Jumalate aed; Andersson, Lars. Katkukuninga legend; Erkelius, Per Agne. Unistus Johannesest; Kõvamees, Raissa. Kahe väina vahel.

  18. Iirlaste uskumatu edu kivilinnas New Yorgis / Tambet Kaugema

    Index Scriptorium Estoniae

    Kaugema, Tambet

    1998-01-01

    Ameerika Ühendriikide rahvusliku raamatuauhinna laureaadid: Alice McDermott (ilukirjanduse auhind, romaan 'Charming Billy'), Edward Ball (aimekirjanduse auhind, 'Slaves in the family'), Gerald Stern (luuleauhind, 'This time'), Louis Sachar (noorsookirjanduse auhind), John Updike (elutöö auhind)

  19. Eisenhower: Decision-making and Consensus in an Unfamiliar Context

    Science.gov (United States)

    2015-05-17

    particularly among parochial government leaders, required all the considerable experience and skill that Eisenhower possessed. The National Security...International and Regional Studies. Princeton, NJ: Princeton University Press, 2004. Pops, Gerald M. Ethical Leadership in Turbulent Times

  20. Area Handbook Series. Cote D’Lvoire; A Country Study

    Science.gov (United States)

    1988-11-01

    production; Mimi Cantwell, Sharon Costcllo, Vincent Ercolano, Ruth Nieland, and Sharon Schultz edited the chapters; Beverly Wolpert performed the final...John Dixon (ed.), Social Welfare iniAfrica. (Cofpara- tive Social Welfare Series.) London: Groom Helh, 1987. Bourke , Gerald. "A Tarnished Miracle...nm Bourke , Gerald. A Tarnished Miracle," Africa Report, 312, No. 6, Noveiilei -Dcemiber 1987, 62-64.’ brayto’n, Abbojt A. Stability and

  1. Propulsion Systems Panel deliberations

    Science.gov (United States)

    Bianca, Carmelo J.; Miner, Robert; Johnston, Lawrence M.; Bruce, R.; Dennies, Daniel P.; Dickenson, W.; Dreshfield, Robert; Karakulko, Walt; Mcgaw, Mike; Munafo, Paul M.

    1993-01-01

    The Propulsion Systems Panel was established because of the specialized nature of many of the materials and structures technology issues related to propulsion systems. This panel was co-chaired by Carmelo Bianca, MSFC, and Bob Miner, LeRC. Because of the diverse range of missions anticipated for the Space Transportation program, three distinct propulsion system types were identified in the workshop planning process: liquid propulsion systems, solid propulsion systems and nuclear electric/nuclear thermal propulsion systems.

  2. European Bulletin of Himalayan Research (EBHR) Number 14, 1998

    OpenAIRE

    South Asia Institute, Heidelberg University, Germany; (CNRS) Centre National de la Recherche Scientifique, France; (SOAS) School of Oriental and African Studies, UK

    1998-01-01

    Graham Clarke : An Appreciation by Ben Campbell; Innovations in Traditional Crafts by Nager and Hunza; In the 20th Century by Jurgen Wasim Frembgen; Work and Nutrition in High Asia by Hiltrud Herbers; The Restoration of Baltit fort by Stefano Bianca; Seasonal Migration in Western Nepal by Satya Shrestha; On Francis Buchanan Hamilton's Account of the Kingdom of Nepal by Marie Lecomte-Tilouine; Credit Systems and Urban Development in Nepal by Michael Muhlich; Ladakh Studies, 8th Colloquium, Moe...

  3. World Epidemiology Review, Number 97.

    Science.gov (United States)

    1978-07-21

    34Trichophyton" and"Epidermophyton" which can also cause lesions on skin, nails and hair. [Text] [Bahia Bianca LA NUEVA PROVINCIA in Spanish 1 Jun 78 p 19] 7717...the disease but are given anyway to prevent extra infection from bacteria ," she said. "We did not have any warning about the disease but...sulpha drugs could produce unpleasant side- effects and could also lead to the emergence of bacteria resistant to such drugs. : Dr Chowdhury

  4. Comparison of cultivars of ornamental crop Gerbera jamesonii on production of spider mite-induced volatiles, and their attractiveness to the predator Phytoseiulus persimilis.

    Science.gov (United States)

    Krips, O E; Willems, P E; Gols, R; Posthumus, M A; Gort, G; Dicke, M

    2001-07-01

    We investigated whether volatiles produced by spider mite-damaged plants of four gerbera cultivars differ in attractiveness to Phytoseiulus persimilis, a specialist predator of spider mites, and how the mite-induced odor blends differ in chemical composition. The gerbera cultivars differed in resistance, as expressed in terms of spider mite intrinsic rate of population increase (rm). In order of increasing resistance these were Sirtaki, Rondena, Fame, and Bianca. To correct for differences in damage inflicted on the cultivars, we developed a method to compare the attractiveness of the blends, based on the assumption that a larger amount of spider mite damage leads to higher attraction of P persimilis. Spider mite-induced volatiles of cultivars Rondena and Bianca were preferred over those of cultivar Sirtaki. Spider mite-induced volatiles of cultivars Sirtaki and Fame did not differ in attractiveness to P. persimilis. Sirtaki plants had a lower relative production of terpenes than the other three cultivars. This was attributed to a low production of cis-alpha-bergamotene, trans-alpha-bergamotene, trans-beta-bergamotene, and (E)-beta-farnesene. The emission of (E)-beta-ocimene and linalool was lower in Sirtaki and Fame leaves than in Bianca and Rondena. The importance of these chemical differences in the differential attraction of predatory mites is discussed.

  5. Key Lake mine water spill: further clean-up not required

    International Nuclear Information System (INIS)

    Potvin, R.

    1984-02-01

    The Atomic Energy Control Board (AECB) has concluded that no additional remedial measures are warranted with regard to the mine water spill which occurred in early January at the Key Lake Mining Corporation facility in northern Saskatchewan, and has advised the company to reconsider its proposal for clean-up of the adjoining Gerald Lake basin. On January 5, an estimated 87 million litres of mine water was accidentally released to the environment when a water storage reservoir at the mine site overflowed. The spilled water flowed into the adjoining Gerald Lake catchment area where it has remained adequately contained

  6. The SMO-COIN Nexus: Using Social Movement Theory to Demobilize Insurgency

    Science.gov (United States)

    2009-06-01

    individual members.74 Frances FitzGerald describes the NLF activities in her book Fire in the Lake as a process of slow integration as the NLF cadre...Guerilla War.” 75 Frances FitzGerald, Fire in the Lake (Boston: Little, Brown and Company, 1972), 155-182. 76 Once organized and mobilized, the...to emerge from the bourgeoisie . By 1957, over 90,000 individuals were engaged in foreign and domestic trading and another 9,000 in real estate sales

  7. 77 FR 536 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-05

    ... INFORMATION: Electronic Access You may see all the comments online through the Federal Document Management..., except Federal holidays. Privacy Act: Anyone may search the electronic form of all comments received into...), Gerald R. Curran (PA), Shawn K. Fleming (PA), Daniel C. French (VA), Garry W. Garrison (WI), Gregory L...

  8. The Military Family: A Selected Bibliography. Revision

    Science.gov (United States)

    1990-11-01

    Commercial (717) 245-3660. "A healthy family environment is a force multiplier." - General John A. Wickham, Jr. NTiS C’. - Statement "A" per telecon...11. Kreyche, Gerald F. "Day Care: The New Surrogacy ." USA TODAY, Vol. 118, September 1989, pp. 91-93. Landrum, Cecile S. "The Changing Military

  9. 75 FR 10295 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-03-05

    ...; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5.... Place: Legacy Hotel and Meeting Center, 1775 Rockville Pike, Rockville, MD 20852. Contact Person: Gerald... evaluate contract proposals. Place: Legacy Hotel and Meeting Center, 1775 Rockville Pike, Rockville, MD...

  10. Baltoscandal näitas Euroopa absurdi / Tiiu Laks

    Index Scriptorium Estoniae

    Laks, Tiiu, 1984-

    2010-01-01

    Rakveres 10. juulil lõppenud 11. rahvusvahelisest teatrifestivalist Baltoscandal. Prantslase Gerald Kurdiani kontsertetendusest "This is the Hello Monster!". Riina Maidre ja Maike Londi kontsertetendusest "PostUganda". Philippe Quesne'i ja tema trupi Vivarium Studio lavastusest "Big Bang". Taani tantsija Mette Ingvartseni lavastusest "Giant City". Akhe inseneriteatri lavastusest "Faust. 2360 sõna". Hollandi trupi Dood Paard lavastusest "Answer Me"

  11. An overview on hepatitis C virus genotypes and its control

    African Journals Online (AJOL)

    Faisal Nouroz

    2015-06-10

    Jun 10, 2015 ... Contents. 1. History and structure of hepatitis C virus . .... Dental treatment. 1.6. IVDU ..... [29] Ray Stuart C, Thomas David L. Hepatitis C. In: Mandell Gerald ... Lamballerie X, de Micco P. Analysis of the 50 non coding region.

  12. Counterpoint: Practice versus Process--Rigidity of Reinforcement Requirements Results in Regressive Research: A Reply to Ward.

    Science.gov (United States)

    Biederman, Gerald B.; Davey, Valerie A.

    1995-01-01

    This counterpoint responds to Phillip Ward's commentary on a study by Gerald Biederman and others which concluded that verbal reinforcement in combination with interactive modeling strategies may produce confusion in children with language/learning difficulties. The counterpoint argues that the commentary indicates problems with semantics and with…

  13. 75 FR 12561 - Delaware River and Bay Oil Spill Advisory Committee; Meeting Cancelled

    Science.gov (United States)

    2010-03-16

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [Docket No. USCG-2008-0333] Delaware River and Bay Oil Spill Advisory Committee; Meeting Cancelled AGENCY: Coast Guard, DHS. ACTION: Notice of cancellation of...) is cancelled. FOR FURTHER INFORMATION CONTACT: Gerald Conrad, Liaison to the DFO of the DRBOSAC, (215...

  14. IV rahvusvaheline turismikonverents "Ma armastan Eestimaad!"

    Index Scriptorium Estoniae

    2009-01-01

    25. septembril Meriton Conference&Spa Hotellis toimunud turismikonverentsist Lühiülevaade Juhan Partsi, Maria Alajõe, Paul Flattersi, Gerald Broddelezi, Raul Rebase, Raivo Vare, Birgit Prikki, Mikko Fritze, Andres Toode, Merle Adamsi ja Helen Mahmastoli ettekannetest, konverentsi moderaator oli Eesti Kaubandus- ja Tööstuskoja peadirektor Siim Raie

  15. BOOK REVIEWS / RECENSIONI

    African Journals Online (AJOL)

    User

    Prendi avviso o lettore. Questa pagina fu scritta per amore. (“Esergo”) l poeta stabilisce un dialogo ideale con il lettore. Significativo è il passo che Maffeo pone come presentazione alla sua raccolta, tratto dal poeta inglese Gerald Manley Hopkins: “A che servono le opere d'arte? Ad educare, a essere esempi. Produrre […] ...

  16. Graduates\\' Perception of University Programmes and Their ...

    African Journals Online (AJOL)

    Graduates\\' Perception of University Programmes and Their Relevance to Employment: A study of University of Nairobi Graduates (1991-1998). Gerald N Kimani. Abstract. No Abstract Available Africa Development Vol. XXX (1&2) 2005: 68-85. http://dx.doi.org/10.4314/ad.v30i1.22213 · AJOL African Journals Online.

  17. 'The Politics of the Womb': Women, Politics and the Environment in ...

    African Journals Online (AJOL)

    'The Politics of the Womb': Women, Politics and the Environment in Pre-Colonial Chivi, Southern Zimbabwe, c.1840 to 1900. Gerald Chikozho Mazarire. Abstract. No Abstract Available Zambezia (2003), XXX (i): 35-50. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  18. Homme kell 18 avatakse Tallinna Kunstihoones NIFKA näitus...

    Index Scriptorium Estoniae

    2006-01-01

    Kapitali mõistet uuriv rahvusvaheline grupinäitus "Kapital (see veab meid alt)". Kuraator Simon Sheikh, osalejad loetletud. Avaldatakse ka raamat, kus tutvustatakse Will Bradley, Katja Diefenbachi, Stephan Geene'i, Brian Holmes'i, Trude Iverseni, Oleg Kirejevi, Isabell Lorey, Gerald Rauningi ja Natascha Sadr Haghighiani loomingut ja esseesid

  19. 76 FR 75882 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2011-12-05

    ... Memorial Drive, Kansas City, Missouri 64198-0001: 1. Gerald L. Lentfer, Firth, Nebraska; Steven J. Miller... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C... paragraph 7 of the Act (12 U.S.C. 1817(j)(7)). The notices are available for immediate inspection at the...

  20. Understanding and Reducing Off-Duty Vehicle Crashes Among Military Personnel

    Science.gov (United States)

    2010-01-01

    Safety Administration, 2001. Heino, Adriaan, Hugo H. van der Molen, and Gerald J. S. Wilde, “Differences in Risk Experience Between Sensation Avoiders...Safety Research, Vol. 39, No. 3, 2008, pp. 311–319. References 95 Philip, Pierre, Jacques Taillard, Patricia Sagaspe, Cedric Valtat, Montserrat

  1. 76 FR 11252 - National Institute on Drug Abuse; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-01

    ... review and evaluate grant applications. Place: Ritz-Carlton Hotel at Pentagon City, 1250 South Hayes...: March 9, 2011. Time: 5 p.m. to 6:30 p.m. Agenda: To review and evaluate grant applications. Place: Ritz-Carlton Hotel at Pentagon City, 1250 South Hayes Street, Arlington, VA 22202. Contact Person: Gerald L...

  2. Textbook America.

    Science.gov (United States)

    Karp, Walter

    1980-01-01

    Focuses on how political attitudes have been influenced by American history textbooks at various times throughout history. Excerpts from traditional and revisionist textbooks are presented, with emphasis on "America Revised" by Frances FitzGerald. Journal available from Harper's Magazine Co., 2 Park Ave., New York, NY 10016. (DB)

  3. Bracey's Applesauce.

    Science.gov (United States)

    Packer, Arnold

    1999-01-01

    A professional economist criticizes Gerald Bracey's view that the condition of public education has little to do with the state of the nation's economy. Most studies indicate that education contributes to growing productivity, higher wages, and a sound economy. Education can serve the nation's economic needs without sacrificing education's other…

  4. 76 FR 20076 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-04-11

    ... in favor of granting a Federal vision exemption to James H. Corby, Thomas E. Moore, and John F... 23 exemption applications, FMCSA exempts, Jody L. Baker, Gary W. Balcom, Jimmie L. Blue, Ronald Cook, James H. Corby, Bobby D. Cox, Wesley M. Creamer, Gerald S. Dennis, Cleveland E. Edwards, Thomas...

  5. Võimsaim jõulusõnum / Kersti Inno

    Index Scriptorium Estoniae

    Inno, Kersti, 1954-

    2006-01-01

    J. S. Bachi "Jõuluoratoorium" Eesti Filharmoonia Kammerkoori ja Tallinn Baroque Orkestri esituses 21. dets. Vanemuise kontserdimajas, 22. dets. Pärnu kontserdimajas ja 23. dets. Estonia kontserdisaalis. Benjamin Britteni kantaadi "Püha Nicolaus" ja Gerald Finzi "In Terra Pax" esitusest 16. ja 17. dets. Tallinnas Niguliste kirikus

  6. Maramaa elust poksi ja graffitini / Andres Lepik, Ott Aardam ; interv. Gert Kiiler

    Index Scriptorium Estoniae

    Lepik, Andres

    2008-01-01

    Ugala teater alustas 89. hooaega. Esimese poole plaanitud esietendused : Toomas Suumani "Linnapea" Heiki Raudla raamatu "August Maramaa aeg" järgi, lavastaja Andres Lepik. Ott Aardami noortetükist "Poks", lavastaja autor. Gerald Sibleyras' "Grafiti", lavastaja Taago Tubin. Silvia Soro jõulunäidend "Inetu pardipoja" ainetel, lavastaja Oleg Titov

  7. A Mental Health Consultation Program for Project Head Start.

    Science.gov (United States)

    Kawin, Marjorie R.

    The Psychological Center provided a family oriented mental health consultation service to 17 delegate agencies who had contracts with Head Start programs in 1966-67. This paper presents an overview of the services which an interdisciplinary staff of 52 professionals provided to 6,780 families and 1,500 agency staff members. Gerald Caplan's (1964)…

  8. School Law Update...Preventive School Law.

    Science.gov (United States)

    Jones, Thomas N., Ed.; Semler, Darel P., Ed.

    A wide variety of contemporary legal issues are addressed in the 15 separate papers that make up this volume. The introductory chapter by William C. Bednar, Jr. provides a broad-based rationale for "Preventive School Law." Chapters 2 and 3, both by Gerald A. Caplan, review "Current Issues in Reduction-in-Force" and "First Amendment Claims by…

  9. Education and the Environment: Creating Standards-Based Programs in Schools and Districts

    Science.gov (United States)

    Lieberman, Gerald A.

    2013-01-01

    In this timely book, curriculum expert Gerald A. Lieberman provides an innovative guide to creating and implementing a new type of environmental education that combines standards-based lessons on English language arts, math, history, and science with community investigations and service learning projects. By connecting academic content with local…

  10. Author Details

    African Journals Online (AJOL)

    Innovation. ... Mazarire, Gerald Chikozho. Vol 24 (2002) - Articles Ethical considerations for Zimbabwean archives and the digital challenge. Abstract. ISSN: 1025-8892. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  11. Genetic diversity, population structure and marker trait associations ...

    Indian Academy of Sciences (India)

    Supplementary data: Genetic diversity, population structure and marker trait associations for seed quality traits in cotton (Gossypium hirsutum). Ashok Badigannavar and Gerald O. Myers. J. Genet. 94, 87–94. Table 1. List of cotton germplasm lines used in this study. Germplasm no. Cultivar. Region. Germplasm no. Cultivar.

  12. Between Native American and Continental Philosophy: A Comparative Approach to Narrative and the Emergence of Responsible Selves

    Science.gov (United States)

    Richardson, Troy

    2012-01-01

    This essay explores some of the affinities between current theories of North American Indigenous trickster narratives and continental philosophy where they are both concerned with the question of responsibility in subject formations. Taking up the work of Judith Butler, Franz Kafka and Gerald Vizenor, the author works to show how both continental…

  13. Eating disorders in males: A review

    African Journals Online (AJOL)

    Adele

    regarding the abnormality of reproductive hormone function ... This paper reviews the existing literature on males with eating disorders in an ... through the work of Gerald Russell.7 The term “bulimia” is .... a critical time for adolescents, as an eating disorder could po- ..... Gender Related Aspects of Eating Disorders: A Guide.

  14. Ford: Not a Lincoln but a Hayes? A Lesson in History and Political Science

    Science.gov (United States)

    Donnangelo, John A.

    2007-01-01

    History or social studies teachers are constantly striving to make the past come alive for their students and to help them see that not only does the past relate to the present, but it can also give insights into the future. The recent passing of former President Gerald R. Ford provides social studies teachers with just such an opportunity. Ford's…

  15. 75 FR 28323 - Proposed Collection; Comment Request for Regulation Project

    Science.gov (United States)

    2010-05-20

    ... assured of consideration. ADDRESSES: Direct all written comments to Gerald Shields, Internal Revenue... regulations provide rules authorizing employers to establish electronic systems for use by their tipped... amount of income tax and FICA tax to withhold from the tipped employee's wages. Current Actions: There...

  16. African Journal of Social Work - Vol 4, No 2 (2014)

    African Journals Online (AJOL)

    The role of financial institutions towards affordable housing to urban middle income earners: Evidence from Kampala City, Uganda · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Kenneth Atuheire, Gerald Kagambirwe Karyeija, 1-37 ...

  17. Tundlikud ja tundelised / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-

    2001-01-01

    Sisu : David Herbert Lawrence. Vikerkaar; Kazuo Ishiguro. Hõljuva maailma kunstnik; Vassil Bõkav. Toru; Torcuato Luca de Tena. Jumala käega; Roxanne Pulitzer. Carrie ja Gracie; Graham Robb. Victor Hugo; Scott Adams. Dilberti printsiip; Andrea Fehringer, Gerald Reischl, Clemens Stadlbauer. Sajandi suurimad pigilinnud; Gertrud Teusen. Jonniiga

  18. Plaadid / Jürgen Tamme

    Index Scriptorium Estoniae

    Tamme, Jürgen

    2005-01-01

    Uutest heliplaatidest A Guy Called Gerald "To All Things What They Need", "World Of Mouth", Wet Wet Wet "The Greatest Hits", Martika "Toy Soldiers. The Best Of", Toby Keith "Greatest Hits", Electric Six "Senor Smoke", Static-X "Beneath...Between...Beyond...Rarities", Judas Priest "Angel Of Retribution"

  19. Science and Technology Metrics

    Science.gov (United States)

    2005-01-01

    CONTENTS,1992, Vol 35, Iss AUG, pp 3 12 Garfield E, "Parascience, Pseudoscience , and Political Power Holton,Gerald on the Antiscience Phenomenon And Why...1993, Vol 25, Iss JUN, pp 3 9 Garfield E, "The Science Religion Connection an Introduction to Science and Religion From Warfare over Sociobiology to a

  20. Training Needs in Gerontology. Hearings, Special Committee on Aging, United States Senate. Part 2.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    At the second day of hearings on training needs in gerontology the witnesses were Stephen Kurzman accompanied by Arthur S. Flemming, John Lapp, Gerald D. LaVeck; George Maddox; Elias Cohen; Wilma Donahue; Brin Hawkins with Lettie Graves and Yolanda Owens; and John B. Martin. (MS)

  1. Picking the Bone: The B-1 Bomber as a Platform for Innovation

    Science.gov (United States)

    2010-06-01

    August 1974 amidst the Watergate scandal . Vice President Gerald Ford took office and retained James Schlesinger as his secretary of defense...Jones assumed command in 1974 amidst the Nixon presidential scandal and the B-1A design testing dilemma. General Jones understood Schlesinger‘s

  2. 75 FR 53020 - Proposed Collection: Comment Request for Regulation Project

    Science.gov (United States)

    2010-08-30

    ... record for the tax imposed on the entry of taxable fuel into the U.S. and revises definition of ``enterer.... ADDRESSES: Direct all written comments to Gerald Shields, Internal Revenue Service, Room 6129, 1111... the administration of any internal revenue law. Generally, tax returns and tax return information are...

  3. ANTIANDROGENIC EFFECTS OF VINCLOZOLIN ON MALE RATS ARE PARTIALLY ATTENUATED BY TESTOSTERONE PROPIONATE

    Science.gov (United States)

    ANTIANDROGENIC EFFECTS OF VINCLOZOLIN ON MALE RATS ARE PARTIALLY ATTENUATED BY TESTOSTERONE PROPIONATECynthia Wolf1,2 , Joe Ostby1, Jonathan Furr 1, Gerald A. LeBlanc2, and L. Earl Gray, Jr.11 US Environmental Protection Agency, NHEERL, RTD, RTP, NC 27711, 2 Departmen...

  4. Taking Sides: Ethics, Politics and Fieldwork in Anthropology & All Tomorrow's Cultures: Anthropological Engagements with the Future

    Directory of Open Access Journals (Sweden)

    Aimar Ventsel

    2011-12-01

    Full Text Available Review of the publications Taking Sides: Ethics, Politics and Fieldwork in Anthropology. Edited by Heidi Armbruster and Anna Lærke. New York, Oxford: Berghahn Books 2008, 258 pages; and Samuel Gerald Collins, All Tomorrow's Cultures: Anthropological Engagements with the Future. New York, Oxford: Berghahn Books 2008, 140 pages.

  5. Taking Sides: Ethics, Politics and Fieldwork in Anthropology & All Tomorrow's Cultures: Anthropological Engagements with the Future

    Directory of Open Access Journals (Sweden)

    Aimar Ventsel

    2012-10-01

    Full Text Available Review of the publications Taking Sides: Ethics, Politics and Fieldwork in Anthropology. Edited by Heidi Armbruster and Anna Lærke. New York, Oxford: Berghahn Books 2008, 258 pages; and Samuel Gerald Collins, All Tomorrow's Cultures: Anthropological Engagements with the Future. New York, Oxford: Berghahn Books 2008, 140 pages.

  6. The Development of a Marketing Program for Womack Army Medical Center Fort Bragg, North Carolina

    Science.gov (United States)

    1997-05-01

    Its successful implementation requires organizational commitment to market -based principles . This research assesses the design, function, and success...Concept of Marketing ," Journal of Marketing , (January 1969): 10-15. 60 Kotler , Philip and Gerald Zaltman. "Social Marketing : An Approach to Planned... market based enterprise. Its successful implementation requires organizational commitment to market -based principles . This research assesses the design

  7. (Bos grunniens) in Qinghai-Tibetan Plateau

    African Journals Online (AJOL)

    DR. NJ TONUKARI

    2012-10-30

    Oct 30, 2012 ... Qinghai-Tibetan Plateau, as it represents a unique bovine species adapted to ..... al., 1993; Udina et al., 2003), mastitis caused by. Staphylococcus sp. ... for prevention and treatment in many cases (Gerald et al., 2003). But in ...

  8. 76 FR 17930 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-31

    ... Nanotechnology. Date: July 12-13, 2011. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate grant applications... review and evaluate grant applications. Place: Bethesda North Marriott Hotel & Conference Center, 5701 Marinelli Road, Bethesda, MD 20852. Contact Person: Gerald G. Lovinger, PhD, Scientific Review Administrator...

  9. Entre palavras e ações: o crime na linguagem de Guimarães Rosa

    Directory of Open Access Journals (Sweden)

    Valda Suely Silva Verri

    2010-12-01

    seu advogado, possibilita ao leitor perceber a ambiguidade de seu discurso e refletir sobre sua culpa. Para tanto, empregamos a terminologia de Gerard Genette e as considerações teóricas sobre o narratário de Gerald Prince

  10. The Effect of Material Strength on Segment Penetration Behavior

    Science.gov (United States)

    1993-04-01

    Muenchen GERMANY Royal Armament R&D Establishment ATTN: I. Cullis Fort Halstead Sevenoaks, Kent TN14 7BJ ENGLAND Centre d’Etudes de Gramat ATTN...SOLVE Gerald 46500 Gramat FRANCE 2 Defense Research Establishment Suffield ATTN: C. Weickert D. Mackay Ralston, Alberta, TOJ 2N0 Ralston CANADA Defense

  11. An Evolutionary Approach to the Biological Management of Invasive Brown Treesnakes (Boiga irregularis) on Guam

    Science.gov (United States)

    2012-03-14

    only two snake species on the Guam, the other of which is a burrowing blind snake Ramphotyphlops braminus (possibly introduced as well), and none of...descriptions of three new species. Systematic Parasitology 1:127-140. Roberts, L. S. and J. J. Janovy. 2005. Gerald D. Schmidt and Larry S. Roberts

  12. 78 FR 78477 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-12-26

    ...) James T. Sullivan (KY) David C. Sybesma (ID) Robert N. Taylor (OR) Scott A. Taylor (WV) Temesgn H. Teklezig (WA) Matthew K. Tucker (MN) Victor H. Vera (TX) Stephen D. Vice (KY) Larry J. Waldner (SD) Karl A...) Jerry L. Schroder (IL) Gerald J. Shamla (MN) Stephen E. Shields (KY) Peter M. Shirk (PA) William C...

  13. Manhunting: Counter-Network Organization for Irregular Warfare

    Science.gov (United States)

    2009-09-01

    Buenos Aires, Argentina Israeli Mossad pursued Adolf Eichmann . Eichmann was finally identified in Buenos Aires. Apprehended on his way home, he...Malkin and Harry Stein, Eichmann in My Hands (New York: Warner Books, May 1990). Mossad is the Israeli intelligence service. 288. “Dr. Gerald Bull

  14. Discussion panel: field test design & data analysis

    Science.gov (United States)

    Daniel M. Schmitt; William E. Waters; B. Leo Cadogan; Gerald S. Walton

    1985-01-01

    I think it is time to open the panel. On my left respectively are Bill Waters, Professor of Entomology and Forestry, University of California, Berkeley; Gerald S. Walton, Biometrician, Northeastern Forest Experiment Station, Hamden; and Leo Cadogan, Forest Pest Management Institute, Canadian Forestry Service, Sault Ste. Marie, Ontario. My name is Dan Schmitt, Program...

  15. Beyond clinical trials: Cross-sectional associations of combination ...

    African Journals Online (AJOL)

    3 Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of ..... median command and a series of χ2 tests, respectively (Table 1). ...... 2012;379(9835):2439-2448. https://doi.org/10.1016/s0140-6736(12)60917-9 .... Gerald A, Reynolds C. Characteristics and applications of the Revised Children's ...

  16. A photographic atlas of selected regions of the Milky Way

    National Research Council Canada - National Science Library

    Barnard, Edward Emerson; Frost, Edwin Brant; Calvert, Mary R; Dobek, Gerald Orin

    2011-01-01

    .... It also includes a biography of Barnard and his work, a Foreword and Addendum by Gerald Orin Dobek describing the importance of the Atlas and additions to this volume, and a pull-out section with a mosaic of all 50 plates combined in a single panorama"--

  17. Electric dipole moments of the nucleon and light nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Wirzba, Andreas

    2014-08-15

    The electric dipole moments of the nucleon and light ions are discussed and strategies for disentangling the underlying sources of CP violation beyond the Kobayashi–Maskawa quark-mixing mechanism of the Standard Model are indicated. Contribution to “45 years of nuclear theory at Stony Brook: a tribute to Gerald E. Brown”.

  18. A Simple Demonstration of the High-Temperature Electrical Conductivity of Glass

    Science.gov (United States)

    Chiaverina, Chris

    2014-01-01

    We usually think of glass as a good electrical insulator; this, however, is not always the case. There are several ways to show that glass becomes conducting at high temperatures, but the following approach, devised by Brown University demonstration manager Gerald Zani, may be one of the simplest to perform.

  19. Reducción de la desnutrición crónica en el Perú: propuesta para una estrategia nacional.

    Directory of Open Access Journals (Sweden)

    Amalia Flores Vidalón

    2002-06-01

    Full Text Available THE GERALD J. AND DOROTHY R. FRIEDMAN SCHOOL OF NUTRITION SCIENCE AND POLICY AT TUFTS UNIVERSITY. Reducción de la desnutrición crónica en el Perú: propuesta para una estrategia nacional. Medford, Massachussetts: Tufts University, 2001.

  20. 75 FR 60508 - Proposed Collection: Comment Request for Regulation Project

    Science.gov (United States)

    2010-09-30

    ... ``direct rollover'' transaction. These provisions also require qualified pension plans and tax-sheltered... comments concerning an existing final regulation, EE-43-92 (TD 8619), Direct Rollovers and 20- Percent... November 29, 2010 to be assured of consideration. ADDRESSES: Direct all written comments to Gerald Shields...

  1. Coefficient estimates of negative powers and inverse coefficients for ...

    Indian Academy of Sciences (India)

    and the inequality is sharp for the inverse of the Koebe function k(z) = z/(1 − z)2. An alternative approach to the inverse coefficient problem for functions in the class S has been investigated by Schaeffer and Spencer [27] and FitzGerald [6]. Although, the inverse coefficient problem for the class S has been completely solved ...

  2. Political Communication Yearbook 1984.

    Science.gov (United States)

    Sanders, Keith R., Ed.; And Others

    Focusing on current scholarship in the evolving field of political communication, this publication is organized in three sections. Part 1, "Current Perspectives on the Spiral of Silence," features essays by Charles T. Salmon and F. Gerald Kline, Klaus Merten, Carroll J. Glynn and Jack M. McLeod, and a response by the theory's original…

  3. Software Life Cycle Management Workshop (2nd) August 21-22, 1978, Atlanta, Georgia.

    Science.gov (United States)

    1978-08-01

    paid "experienced" programmer where a freshly trained beginner is EthnoTECHnical Review Handbook available. Daniel P. Freedman and Gerald M. Weinberg...operators could make notes or draw flowcharts . At the end of the study period, the original program and all N = total frequency of operands scrap paper

  4. Inimene kronesteetilise kaameraga / Andreas W

    Index Scriptorium Estoniae

    Andreas W, pseud., 1969-

    2011-01-01

    Fotofilmifestival 14. oktoobril kinos Sõprus. Fotofilmist. Rahvusvahelisest fotofilmi konkursist "Ajatu lugu". Grand prix' pälvis Anu-Laura Tuttelberg, 2. koha Andri Allas ja Krõõt Tarkmeel, 3. koha Gerald Assouline (Prantsusmaa). Lühidalt festivalil näidatud Gusztáv Hámosi fotofilmidest (Saksamaa)

  5. Guidelines for the design of a healing garden for the rehabilitation of psychiatric patients

    Directory of Open Access Journals (Sweden)

    Chantal Erbino

    2015-06-01

    Full Text Available Healing gardens are green spaces designed to promote and improve health and well-being for people suffering from illness. This paper proposes a methodology for defining a master plan for healing gardens. The methodology is based on site analysis (identification, limitations and potentials of the area and the evaluation of user needs (patients, staff, relatives. The aim of the master plan is to provide guidelines for the definition of the executive plan, and to set up a sufficiently flexible project suitable for future new categories of patients, according to the different needs of the regional health authorities. The methodology has been applied to a case study: this paper considers the design of the healing garden of a building named Villa Bianca, part of the wider complex of the clinic for mental disorders Villa di Salute located in Trofarello (in the province of Turin, Piedmont, Italy. The main kinds of disturbances treated at Villa di Salute are schizophrenia and personality disorders; there are also some patients with severe depression. At the present time the building and the garden of Villa Bianca are not being used and are undergoing renovation.

  6. Monitoring of pistachio (Pistacia Vera) ripening by high field nuclear magnetic resonance spectroscopy.

    Science.gov (United States)

    Sciubba, Fabio; Avanzato, Damiano; Vaccaro, Angela; Capuani, Giorgio; Spagnoli, Mariangela; Di Cocco, Maria Enrica; Tzareva, Irina Nikolova; Delfini, Maurizio

    2017-04-01

    The metabolic profiling of pistachio (Pistacia vera) aqueous extracts from two different cultivars, namely 'Bianca' and 'Gloria', was monitored over the months from May to September employing high field NMR spectroscopy. A large number of water-soluble metabolites were assigned by means of 1D and 2D NMR experiments. The change in the metabolic profiles monitored over time allowed the pistachio development to be investigated. Specific temporal trends of amino acids, sugars, organic acids and other metabolites were observed and analysed by multivariate Partial Least Squares (PLS) analysis. Statistical analysis showed that while in the period from May to September there were few differences between the two cultivars, the ripening rate was different.

  7. The Wildlife Rescue Centre Ripabianca di Jesi (Ancona, data: 2005-2007

    Directory of Open Access Journals (Sweden)

    Cinzia Ciarmatori

    2012-09-01

    Full Text Available Wildlife Recovery Centres are important for the rehabilitation of bird species, particularly those of higher conservation interest. They are also a very useful source of knowledge on bird populations. Located within the Regional Nature Reserve, the Wildlife Recovery Centre CRAS WWF Ripa Bianca of Jesi in cooperation with the Province of Ancona has been a reference point for all those who have found injured birds in the last few years. From 2005-2007 the Centre recovered over 1000 specimens belonging to 50 different species, mainly passerines during breeding period, while raptors were 30%. The most frequent pathologies were due to trauma. Around 50% of the birds have been ringed and released after their data had been recorded according to EURING. The high number of nocturnal birds of prey pulli- particularly Little, Tawny, Longeared and Barn Owls - highlights the need for appropriate sensibilization campaigns. In some cases, progressive re-immission of predators bred in captivity has been carried out.

  8. Communications Style Guide. Fourth Edition

    Science.gov (United States)

    2010-08-01

    Example 2: The general’s dog, obedient and loyal, was the perfect companion . 2. Adverbial modifiers: Adverbial modifiers are usually followed...pronoun in this case. Example 3: Us chefs like to cook.  You wouldn’t say, “Us like to cook,” so the appropriate pronoun here is we. 2...in Chicago Style. Resources for Additional Help:  Alred, Gerald J., Charles T. Brusaw, and Walter E. Oliu. The Business Writer’s Companion

  9. National Dam Safety Program. Clove Lake Dam (NJ 00259) Delaware River Basin, Shimers Brook, Sussex County, New Jersey. Phase I Inspection Report.

    Science.gov (United States)

    1981-08-01

    it be reclassified as low hazard. The spillway will pass the 100-year flood and is considered adequate. e. Ownership. The dam is owned by Clubhouse ...Associates. For information, contact Mr. Gerald Roby, Clubhouse Associates, RD 4, Box 108, Montague, New Jersey 07827. f. Purpose. The Clove Lake Dam...into what appears to be a man-made lake downstream of Clove Lake Dam about 0.5 mile. Although no homes are presently constructed around this downstream

  10. Ambulatory care pavilion takes its place out front by solving multiple needs.

    Science.gov (United States)

    Saukaitis, C A

    1994-09-01

    In sum, this structure exemplifies the fact that high-tech tertiary care medical centers can be user-friendly to the ambulatory health care consumer by serving their routine needs conveniently and efficiently. Says Gerald Miller, president of Crozer-Chester: "The ambulatory care pavilion has enabled Crozer to successfully and efficiently merge physicians' offices with institutional-based services and inpatient services. We are pleased with how the pavilion positions our medical center for the next century.

  11. Mangghuer Embroidery: A Vanishing Tradition

    OpenAIRE

    Aila Pullinen

    2015-01-01

    Aila Pullinen. 2015. Mangghuer Embroidery: A Vanishing Tradition IN Gerald Roche and CK Stuart (eds) Asian Highlands Perspectives 36: Mapping the Monguor, 178-188, 301-332. Visits were undertaken in the years 2001 and 2002 to Minhe Hui and Mangghuer (Tu) Autonomous County, Haidong Municipality, Qinghai Province, China to research and document Mangghuer embroidery. This research is summarized in terms of the history of Mangghuer embroidery, tools and materials, embroidery techniques, embr...

  12. The Family and Medical Leave Act (FMLA): Policy Issues

    Science.gov (United States)

    2013-09-04

    occupations (67.3%) and Management , Business , and Financial occupations (65.0%), and Production occupations (63.7%). Occupations with lower shares of...married a spouse of the same sex, regardless of the employee’s … state of residency.” (U.S. Government, Office of Personnel Management , Fact Sheet: Family ...CRS Report for Congress Prepared for Members and Committees of Congress The Family and Medical Leave Act (FMLA): Policy Issues Gerald

  13. Window of Opportunity: Mitigating Threats from Disruptive Technologies Before Widespread Adoption

    Science.gov (United States)

    2014-09-01

    diffusion.117 Taking a lesson from the issues faced by mitigating the dual-use concerns in the biotechnology field, Mandel and Gerald Epstein...technology combined with online collaboration enables users to make high quality firearm parts and high-capacity magazines by simply downloading a...adoption of EDTs, are very similar to those faced in the biotechnology field. Advances in biotechnology are plagued with dual-use concerns, and the

  14. Gordon Research Conference in Organometallic Chemistry, held August 16-20, 1982 Andover, New Hampshire.

    Science.gov (United States)

    1983-03-01

    A. Gentile, Gerald B. Ansell , Michelle A. Modrik ad "S-usan Zentz, Exxon Research and Engineering Co., "Bimetallic Titanium/Molybdenum Complexes...Fluxional M. Moskovits molecules with Multiple Bonding" University of Toronto "Clusters in Catalysis" Basic Steps as Revealed R. Adam by Triosmium...Andover, N.H. August 16-20, 1982 REGISTRATION LIST Adams , Richard D. Farm 1 Bleeke, John John Yale University Washington University 225 Prospect St

  15. Proceedings of the Annual Day of Scientific Lectures (17th), and Annual Meeting of the National Society of Black Physicists (13th), Held in Baton Rouge, LA on March 21-24, 1990

    Science.gov (United States)

    1990-12-01

    Metropolitian Coca Cola Boston Compact BW -Rf r rfz-rr" c .r fret[ 203 Tomorrow’s job’s will require more education Years of schooling Future needed...Morgan Pennsylvania State Universiiy SPONSORSHIPS Alabama A&M University Students acEulty Marvin Sykes Dr. M. C. George Steven Pearson Michael Henry...Ibraham Francis Nyandeh Gabriel Ndow Melody Mixon Scholarship students selected by Dr. Kennedy Reed Sponsorship students selected by Mr. Gerald Davis

  16. Avastamata aarete päev

    Index Scriptorium Estoniae

    2009-01-01

    Ettevõtluse Arendamise Sihtasutus korraldas Pirita Lillepaviljonis Euroopa Komisjoni ning majandus- ja kommunikatsiooniministeeriumi toetusel 27. mail 2009 Avastamata aarete päeva. Päev oli pühendatud Eesti looduse väärtustamisele. Sõna võtsid EAS Turismiarenduskeskuse direktori asetäitja Marje Braunbrück, looduse- ja rännumees Hendrik Relve, Tallinna Ülikooli rekreatsiooniteaduste osakonna juhataja Mart Reimann ja reisikorraldaja Gerald Broddelez

  17. Resumen de tesis. An ontological view of cardiovascular and metabolic disease progression using genetically modified mice

    OpenAIRE

    Fabbiano, Salvatore

    2014-01-01

    [ES]Las enfermedades metabólicas tienen una tendencia a ocurrir conjuntamente. Cuando esto sucede, el riesgo de desarrollar otras enfermedades relacionadas aumenta de manera significativa. Síndrome metabólico fue descrito inicialmente como Síndrome X por Gerald Reaven de la Universidad de Stanford en 1988, aunque antes varios autores venían advirtiendo sobre el riesgo cardiovascular que implicaba tener dislipidemias, obesidad, hipertensión arterial e intolerancia a la glucosa, ...

  18. Development and Application of Optimization Techniques for Composite Laminates.

    Science.gov (United States)

    1983-09-01

    Institute of Technolgy Air University in Partial Fulfillment of the Requirements for the Degree of Master of Science by Gerald V. Flanagan, S.B. Lt. USAF...global minima [9]. An informal definition of convexity is that any two points in the space can be connected by a straight line which does not pass out of...question. A quick look at gradient information suggests that too few angles (2 for example) will make the laminate sensitive to small changes in

  19. Operations Events Census Report: Volume IV. 1981 through 1985. Sanitized Version.

    Science.gov (United States)

    1991-04-01

    SMITH, BRADY F. 0837 SMITH, BRUCE E. 0638 SMITH, CHARLOTT W. 0837 SMITH, CLIFFORD H. 0869 SMITH, COLIN C. 0483 SMITH, DARWIN 0599 SMITH, DAVID L... COLIN A. 097! MOORE, EDDIE L. 06491 MOORE, GERALD J. 0738 MORACA, STEPHEN L. 0837 MORAN, KEVIN 0599 MORAN, MARY SHANKS 0861 MORAVEC, TIMOTHY 0599...DRIESBACH, ROBERT A. 0599 DROTLEFF, JAMES E. 0746 DRUMMOND, VEE DEE 0636 DRURY , TIMOTHY E. 0920 DUANE, DENNIS 0636 DUBARTON, ANNE EVELYN 0918 DUENAS

  20. Oxidative Damage in Parkinson’s Disease.

    Science.gov (United States)

    1999-10-01

    with a monoclonal antibody column. Proc. Natl. Acad. Sei. USA 89:3375-3379; 1992. [34] Deegan , P.; Shigenaga, M. K.; Park, E. M.; Alperin, P. E...Malonate and MPTP Neurotoxicity Russell T Matthews,* Peter Klivenyi,* Gerald Mueller,* Lichuan Yang,* Marike Wermer,* Craig E. Thomas,t and M. Flint...Biochemicals (Wayland, MA). MDL 101,002 was generously supplied by Dr. Craig Thomas of Hoechst Marion Roussell. Male Sprague-Dawley rats (Charles River

  1. The Annual Department of Defense Procurement Research Symposium (5th), held 17-19 Nov 76, Monterey, California.

    Science.gov (United States)

    1976-11-01

    appropriate cost principles plus routine approval requirements for items such as foreign travel and equipment purchases. Recently a member of Congress...34 pujrchases (Chaptvr 5) are a substantial ele~ment in salps . SOURCES: Adapted from Walter Isard and Gerald J. Karaska. Unclassified Defense and Space...improved ways of doing things. As an innovation travels through the diffusion process, it also passes through its life cycle. A whole literature has grown

  2. CIA’s Role in the Study of UFOs, 1947-90

    Science.gov (United States)

    1997-01-01

    materials relating to UFOs , little changed. 67 In 1964, however, following high- level White House discussions on - what to do if an alien intelligence...12, to secure the recovery of UFO wreckage from Roswell and any other UFO crash sight for scien tific study and to examine any alien bodies recovered...A Die-Hard Issue GINs Role in the Study of UFOs , 1947-90 Gerald K. Haines While Agency concern over UFOs was substantial until the early 1950s, CIA

  3. Human Immunodeficiency Virus (HIV) Research (AIDS)

    Science.gov (United States)

    1991-02-28

    lymphocyte concentration and the Walter Reed Staging System. RV4 Neurobehavioral Consequences of HTLV-III Brain Infection and AIDS Encephalopathy . PI...drug trials and behavioral therapeutic interventions. E. To use the AIDS encephalopathy model to study basic brain structure-function relationships...rCD4) in Infants and Children and in Pregnant Women and Newborns with HIV Infection. O PI: Dr. Gerald Fischer Status: In Review (WRAIR SR then HIVSUBC

  4. Selected Current Acquisitions and Articles from Periodicals

    Science.gov (United States)

    1994-06-01

    OCCUPATIONAL SPECIALTIES--COSTS. Military occupational specialty training cost handbook (MOSB). Indianapolis, Ind. : U.S. Army Finance and Accounting...UNITED STATES--ARMED FORCES--RECREATION-- FINANCE . United States. General Accounting Office. Morale, welfare, and recreation declining funds require...FRANCE O’Sullivan, Edmund. Roofless Money Heads West (Saudi prince buys Euro Disneyland ). MEED 38:2-3 Jun 17 󈨢. FUTURE FitzGerald, Mary C. The Russian

  5. Soviet Tactical Doctrine for Urban Warfare

    Science.gov (United States)

    1975-12-01

    Soviet Area Specialist. Valuable assistance was provided by Mr. Gerald Sullivan and LTC Ray N. Franklin, USMC, of the Advanced Research Projects... Oldenburg 120.8 133.3 12.5 10 Osnabruck 133.6 164.0 30.4 23 Regensburg 123.0 133.5 10.5 9 Remacheid 123.0 135.5 12.5 10 Salzgitter 105.9 117.6 11.7

  6. A Wire Antenna Designed for Space Wave Radiation Over the Earth Using a Genetic Algorithm

    Science.gov (United States)

    1997-12-01

    algorithms. With the assistance of two Air Force Institute of Technology (AFIT) Ph.D. students, Dave Van Veldhuizen and Robert Marmelstein, the second of the...Laboratory, 1992, UCRL-MA-109338 Pt.I. 41. David A. Van Veldhuizen , Brian S. Sandlin, Robert E. Marmelstein, Gary B. Lamont, and Andrew J. Terzuoli...Dr. Ben Munk, Dr. Gerald Burke, and Dr. Ed Altshuler for their kind assistance and for answering my questions. Finally, I would like to thank Dave Van

  7. Quem eram as bruxas de Gardner?

    OpenAIRE

    Duarte, Janluis

    2017-01-01

    Gerald Gardner, considerado fundador da religião neopagã contemporânea conhecida como Wicca, alegava em suas obras ter obtido seus conhecimentos de um grupo de bruxas inglesas tradicionais. O presente artigo coteja o discurso contido nos livros de Gardner com os conhecimentos históricos a respeito de bruxaria na Inglaterra, buscando esclarecer quais foram suas verdadeiras fontes e influências.

  8. The Charitable Trust Model: An Alternative Approach For Department Of Defense Accounting

    Science.gov (United States)

    2016-12-01

    DEFENSE ACCOUNTING 5. FUNDING NUMBERS 6. AUTHOR (S) Gerald V. Weers Jr. 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School...prohibits the incurrence of costs until budget authority is provided; reversing the conditionality of the matching principle accounting logic. In summary...the Board did not believe applying depreciation accounting for these assets would contribute to measuring the cost of outputs produced, or to

  9. Renewable Energy Production from DoD Installation Solid Wastes by Anaerobic Digestion

    Science.gov (United States)

    2016-06-08

    Stensel, Donnie Stallman, Urv Patel, Matthew Higgins , Ambalavanan Jayaraman, Gokhan Alptekin, Steve Dietz, Matthew Cates, and Kerry Libberton 5d. PROJECT...Mark Schmidt, Mr. Chris Simpson, Ms. Tina Springer, Mr. Dan Stewart, Professor Don Veverka, Ms. Corine Weiss, Mr. Gerald Williams, and Capt. Frank...Smith were involved in this demonstration including Ms. Janelle Amador, Mr. Chris Avina, Mr. Cameron Clark, Mr. Cale McPherson, Mr. Tyler Miller, Ms

  10. Field Demonstration and Validation of TREECS (trademark) and CTS for the Risk Assessment of Contaminants on Department of Defense (DoD) Ranges

    Science.gov (United States)

    2017-04-01

    analyzed by the Engineer Research and Develop- ment Command (ERDC) Environmental Laboratory (EL) Environmental Chemistry Branch (ECB) using EPA...diffusion coefficients. Industrial and Engineering Chemistry 58:19–27. Gerald, J. A., B. E. Johnson, and M. S. Dortch. 2012. User guide for applying...Army Engineer Research and Development Center (ERDC) solves the nation’s toughest engineering and environmental challenges. ERDC develops innovative

  11. Predicting Market Direction from Direct Speech by Business Leaders

    OpenAIRE

    Drury, Brett M.; Almeida, José João

    2012-01-01

    Direct quotations from business leaders can communicate to the wider public the latent state of their organization as well as the beliefs of the organization's leaders. Candid quotes from business leaders can have dramatic effects upon the share price of their organization. For example, Gerald Ratner in 1991 stated that his company's products were crap and consequently his company (Ratners) lost in excess of 500 million pounds in market value. Information in quotes from business leaders can b...

  12. ULUSLARARASI İLİŞKİLERDE BAŞARISIZ DEVLETLER SORUNSALI VE BU SORUNSALIN ULUSLARARASI HUKUKA ETKİLERİ

    OpenAIRE

    Özalp, Osman N.

    2014-01-01

    Kavramlarla ilgili bkz. Zartman, I. William (Hg.): Collapsed States: The Disintegration and Restoration of Legitimate Authority, Boulder: Lynne Rienner, 1995; Rotberg, Robert I.: The Failure and Collapse of Nation-States: Breakdown, Prevention and Repair, in: Beisheim, Marianna/Schuppert, Gunnar F.: Staatszerfall und Governance. Baden Baden: Nomos 2007, s. 59-97; Helman, Gerald B./Ratner, Steven B.: Saving Failed States, in: Foreign Policy, 1992 (89), 3-20; Schneckener, Ulrich (Ed.): Fra...

  13. Identification of Biomarkers for Defense Response to Plasmopara viticola in a Resistant Grape Variety

    Directory of Open Access Journals (Sweden)

    Giulia Chitarrini

    2017-09-01

    Full Text Available Downy mildew (Plasmopara viticola is one of the most destructive diseases of the cultivated species Vitis vinifera. The use of resistant varieties, originally derived from backcrosses of North American Vitis spp., is a promising solution to reduce disease damage in the vineyards. To shed light on the type and the timing of pathogen-triggered resistance, this work aimed at discovering biomarkers for the defense response in the resistant variety Bianca, using leaf discs after inoculation with a suspension of P. viticola. We investigated primary and secondary metabolism at 12, 24, 48, and 96 h post-inoculation (hpi. We used methods of identification and quantification for lipids (LC-MS/MS, phenols (LC-MS/MS, primary compounds (GC-MS, and semi-quantification for volatile compounds (GC-MS. We were able to identify and quantify or semi-quantify 176 metabolites, among which 53 were modulated in response to pathogen infection. The earliest changes occurred in primary metabolism at 24–48 hpi and involved lipid compounds, specifically unsaturated fatty acid and ceramide; amino acids, in particular proline; and some acids and sugars. At 48 hpi, we also found changes in volatile compounds and accumulation of benzaldehyde, a promoter of salicylic acid-mediated defense. Secondary metabolism was strongly induced only at later stages. The classes of compounds that increased at 96 hpi included phenylpropanoids, flavonols, stilbenes, and stilbenoids. Among stilbenoids we found an accumulation of ampelopsin H + vaticanol C, pallidol, ampelopsin D + quadrangularin A, Z-miyabenol C, and α-viniferin in inoculated samples. Some of these compounds are known as phytoalexins, while others are novel biomarkers for the defense response in Bianca. This work highlighted some important aspects of the host response to P. viticola in a commercial variety under controlled conditions, providing biomarkers for a better understanding of the mechanism of plant defense and a

  14. INFLUENCE OF DIFFERENT SOURCES OF WATER FOR IRRIGATION ON PEPPER (Capsicum annuum L. YIELD IN GLASSHOUSE CONDITIONS

    Directory of Open Access Journals (Sweden)

    Jasna Šoštarić

    2002-06-01

    Full Text Available The aim of this paper was to determine the influence of different sources of water used for irrigation on the yield of pepper hybrids Cecil F1 and Bianca F1 in the early glasshouse production for the period 1998 - 2000 in the controlled glasshouse conditions in «D.G. – PROMET», Magadenovac, Croatia. Lagoon water and well water were two main sources of water used for irrigation in this experiment. Drip irrigation system was applied for pepper production. In comparison to lagoon water, chemical analyses of well water have shown increased values of the following elements: EC, sodium, potassium, calcium, chlorine, magnesium, bicarbonate, sulphate, iron and boron. Temperature of well water was lower than the allowed minimum and therefore had direct influence on the yield decrease. Consequently, areas which have been irrigated by well water have had problems with accumulation of slime and blocking of sprinklers, disturbed soil structure, fruit deformation and decreased crop yield. Statistical data analysis was conducted by the method of covariation three factorial trial (ABC with three repetitions for each treatment. The trial showed absolute difference regarding water efficiency of irrigation water from two sources, which has also been statistically determined (P<0,05. Furthermore, statistically justified difference in the average weight of the fruit of each investigated pepper hybrid (P<0,05 has been proven. Codependence of «water for irrigation» (A and «pepper hybrid» (B, i.e. (AB is statistically significant as well, and justified at the P<0,05 limit. This means that both pepper hybrids (Cecil F1 i Bianca F1 reacted differently to lagoon water and well water. Factor «year» (C has not proven to be statistically justified, and therefore does not have any significant influence on the crop yield due to controlled conditions in the glasshouse.

  15. Study of 'Redhaven' peach and its white-fleshed mutant suggests a key role of CCD4 carotenoid dioxygenase in carotenoid and norisoprenoid volatile metabolism

    Directory of Open Access Journals (Sweden)

    Tartarini Stefano

    2011-01-01

    Full Text Available Abstract Background Carotenoids are plant metabolites which are not only essential in photosynthesis but also important quality factors in determining the pigmentation and aroma of flowers and fruits. To investigate the regulation of carotenoid metabolism, as related to norisoprenoids and other volatile compounds in peach (Prunus persica L. Batsch., and the role of carotenoid dioxygenases in determining differences in flesh color phenotype and volatile composition, the expression patterns of relevant carotenoid genes and metabolites were studied during fruit development along with volatile compound content. Two contrasted cultivars, the yellow-fleshed 'Redhaven' (RH and its white-fleshed mutant 'Redhaven Bianca' (RHB were examined. Results The two genotypes displayed marked differences in the accumulation of carotenoid pigments in mesocarp tissues. Lower carotenoid levels and higher levels of norisoprenoid volatiles were observed in RHB, which might be explained by differential activity of carotenoid cleavage dioxygenase (CCD enzymes. In fact, the ccd4 transcript levels were dramatically higher at late ripening stages in RHB with respect to RH. The two genotypes also showed differences in the expression patterns of several carotenoid and isoprenoid transcripts, compatible with a feed-back regulation of these transcripts. Abamine SG - an inhibitor of CCD enzymes - decreased the levels of both isoprenoid and non-isoprenoid volatiles in RHB fruits, indicating a complex regulation of volatile production. Conclusions Differential expression of ccd4 is likely to be the major determinant in the accumulation of carotenoids and carotenoid-derived volatiles in peach fruit flesh. More in general, dioxygenases appear to be key factors controlling volatile composition in peach fruit, since abamine SG-treated 'Redhaven Bianca' fruits had strongly reduced levels of norisoprenoids and other volatile classes. Comparative functional studies of peach carotenoid

  16. VOLUME 1: ASIAN HIGHLANDS PERSPECTIVES

    Directory of Open Access Journals (Sweden)

    VARIOUS

    2009-06-01

    Full Text Available Amdo Tibetan Tongue Twisters Blo rtan rdo rje, Charles Kevin Stuart, and Gerald Roche……....7 An Amdo Tibetan Village New Year Trance Medium Ritual Dpal ldan bkra shis and Charles Kevin Stuart …..…...........…53 Calling Back the Lost na53 mʑi53 Tibetan Soul Libu Lakhi, Charles Kevin Stuart, and Gerald Roche ..…........65 Dying Hunters, Poison Plants, and Mute Slaves: Nature and Tradition in Contemporary Nuosu Yi Poetry Mark Bender........................................................................117 The Ĕrsū Shābā Pictographic Writing System Sūn Hóngkāi [translated by Mtsho mo skyid and Gerald Roche with an introduction by Thomas Roche and Gerald Roche] ………............……………………........……..…..159 The Fourth Belmang: Bodhisattva, Estate Lord, Tibetan Militia Leader, and Chinese Government Official Paul K Nietupski …………….….…….….…….…………187 The Horse With Two Saddles: Tamxhwe in Modern Golok Fernanda Pirie ….………........……………………..…………..213 Seating, Money, and Food at an Amdo Village Funeral Rin chen rdo rje and Charles Kevin Stuart ..….…....….…..….237 The Seng ze Village Ma Ni Dkon mchog dge legs and Charles Kevin Stuart ……..….….295 Tibetan Life and Tibetological Discourse: Differences and Recommendations Gerald Roche, Nag tshang grub rgyal, and Mtsho mo skyid…313 A Response to Ways and the Syntax of Noun Phrases in Qīnghăi Chinese Dialects Keith Dede .……..….….….…..……..…..….….…………331 Photo Essay Photo Essayto Essay to Essay Lazi (Lab rtse Construction in Karmatang (Skar ma thang Village Tshe mdo ………………..……..….…….………………..349 Review Wutun. By J Janhunen, M Peltomaa, E Sandman, and Xiawudongzhuo. Keith Slater ….….….……..………...….…..….….….…...367 Story God-door Tshe dpag rnam rgyal ………….….….….…..….….….….373

  17. Chinese Foreign Policy in Transition: Trends and Implications

    Directory of Open Access Journals (Sweden)

    Baohui Zhang

    2010-01-01

    Full Text Available Chinese foreign policy has been transformed in recent years. This article seeks to provide a systematic analysis of the most salient features of the new Chinese foreign policy. It identifies five such features. Based on these features, the article suggests that China is poised to become a true global power. This view differs significantly from Gerald Segal’s famous claim in 1999 that China was no more than a middle power. The article utilizes many current Chinese sources to help readers understand China’s new motives and goals in international and regional affairs.

  18. From Extraterrestrial to Terrestrial Applications

    Science.gov (United States)

    Strobl, G. F. X.; Laroche, G.; Rasch, K.-D.; Hey, G.

    In the early 1950s, Bell Laboratories in the USA investigated possible applications of silicon semiconductors in electronics. While improving transistors, Bell scientists Gerald Pearson and Calvin Fuller invented the first silicon solar cell. That first effort was further improved for applications in remote humid locations by Darryl Chapin [1]. The first experiment with silicon yielded an efficiency of 2.3%. Improvements with regard to the dopants, the metallic contacts to the p- and n-side and the application of an antireflection coating led to efficiencies of 4%. In 1954, cells with 6% efficiency could be reliably manufactured.

  19. Reviews of recent publications

    Directory of Open Access Journals (Sweden)

    2005-01-01

    Full Text Available Chanan, Michael. Cuban Cinema David William Foster Izenberg, Gerald N. Modernism and Masculinity: Mann, Wedekind, Kandisnky through World War I. Aaron J. Cohen Jonsson, Stefan. Subject Without Nation: Robert Musil and the History of Modern Identity. Post-Contemporary Interventions. Albrecht Classen Kaiser, David Aram. Romanticism, Aesthetics and Nationalism. Cambridge Studies in Romanticism 34. Catherine Grimm Lopez de Martinez, Adelaida and Harriet Turner. The Cambridge Companion to the Spanish Novel: From 1600 to the Present. Toni Dorca McCulloh, Mark R. Understanding W.G. Sebald. Peter C. Pfeiffer Peterson, Dale E. Up From Bondage: The Literatures of Russian and African American Soul. Kathleen M. Ahren

  20. An introduction to English grammar

    CERN Document Server

    Nelson, Gerald C

    2013-01-01

    English Language and its usage has become extremely emotive issues in recent years. Recurring discussions in the media have highlighted a growing demand for a return to the study of language after decades of neglect. This book is an introductory descriptive survey, intended for students, teachers and general readers which offers coverage of grammatical topics with sections on spelling, punctuation and exercises.Clear and concise, this much needed third edition of Gerald Nelson and the late Sidney Greenbaum's introduction will be of immense value to students who have little or no experience of

  1. US Army Medical Bioengineering Research and Development Laboratory Annual Progress Report for FY 84. Volume 1

    Science.gov (United States)

    1984-10-01

    guanidIne nitrate, is biodegraded slowly in surface waters alone and relatively rapidly if present with metabolizable carbon, in which case the compound...Operation." AORN Journal 40 (1984):330. Goethals, Gerald B. "So, You Want to be in Movies ?" Today’s OR Nurse 6 (1984):36-37. Goyal, Sagar M., S.A. Schaub...Development Laboratory MR 8-84 (May 1984). Mitchell, Wayne R. Preliminarx Results of Biodegradation Studies for Guanidine Nitrate. US Army Medical

  2. A History of the Acoustics Division of the Naval Research Laboratory: The First Eight Decades 1923 - 2008

    Science.gov (United States)

    2013-08-01

    Wilson 9-Gerald Morris 10-Wayne Kinney 11-Pat Carter 12-Ed Besancon 13-Karen Dudley 14-Mary Rowe 15-Tony Pogue 16-Stephanie Kooney 17-Lisa Pflug 18...Leybourne R.W. Meredith C.T. Mire G.B. Morris V.M. Ross K.D. Savage A.S. Smith 7173 Shallow Water & Coastal Acoustics H.B. Ali M.K...Interview with Dr. Budd B. Adams held on Tuesday 23 April 2008 at 1130 AM EDT (1 hour 30 minutes) [Dr. Adams’ revisions received 14 October 2008

  3. Program "Whip Inflation Now" a jeho vliv na inflaci a nezaměstnanost v USA v 70. letech

    OpenAIRE

    Sirový, Michal

    2012-01-01

    The topic of this thesis is the Gerald Ford's program WIN as a policy aimed at inflation. WIN is certainly determined by the time it was developer in. The essential aspects are unemployment rate, which had reached 9 percents in the 1970s, and the neglect of monetary policy. Ford's announced policy was the exact opposite of that of Nixon's. The infamous saving in the times of crisis was relatively mild, thus the speculations of an attempt of Ford's PR is an explanation. The CPI level had lower...

  4. Cyber Practices: What Can the U.S. Air Force Learn from the Commercial Sector?

    Science.gov (United States)

    2015-01-01

    dam/lockheed/data/isgs/documents/LMCSA%20Ov erview%20Fact%20Sheet_Final%20%282%29. pdf Lunt, Barry, Joseph J. Ekstrom, Sandra Gorka, Gregory Hislop ...Electronics Engineers, 2006, p. 33. 21 Barry Lunt, Joseph J. Ekstrom, Sandra Gorka, Gregory Hislop , Reza Kamali, Eydie Lawson, Richard LeBlanc, Jacob Miller...1 (January 1980 ). 106 Daft, 2008, p. 17. 107 Gerald D. Bell, “Determinants of Span of Control,” American Journal of Sociology 73, no. 1 (1967

  5. The information systems security officer's guide establishing and managing an information protection program

    CERN Document Server

    Kovacich, Gerald L

    2003-01-01

    Information systems security continues to grow and change based on new technology and Internet usage trends. In order to protect your organization's confidential information, you need information on the latest trends and practical advice from an authority you can trust. The new ISSO Guide is just what you need. Information Systems Security Officer's Guide, Second Edition, from Gerald Kovacich has been updated with the latest information and guidance for information security officers. It includes more information on global changes and threats, managing an international information secur

  6. Valentine Chirol'e Gecikmiş Bir Cevap: İngiltere'nin Propaganda Savaşları, Çanakkale, Fitzmaurice ve Diğerleri

    Directory of Open Access Journals (Sweden)

    Altay Cengizer

    2015-04-01

    Full Text Available Gerald Fitzmaurice, Chief Dragoman of the British Embassy in Turkey and British ambassador (1908–1914 Geard Lowther were two important actors of Ottoman-British relations. However, they were not very interested in conveying the political and social developments in Ottoman Empire to London, a situation that led to ignorance and prejudice on the affairs of the Ottoman Empire. The other stuff of the British embassy in İstanbul who had anti-Ottoman feelings also share the blame.

  7. The current status of immunotoxins: an overview of experimental and clinical studies as presented at the Third International Symposium on Immunotoxins.

    Science.gov (United States)

    Uckun, F M; Frankel, A

    1993-02-01

    The Third International Symposium on Immunotoxins was held on June 19-21, 1992 in Orlando, Florida. This symposium was sponsored by NATO, NIH, Pierce Chemical Company, Walt Disney Cancer Institute at Florida Hospital, Duke Comprehensive Cancer Center, Xoma, Immunogen, Seragen, Bristol-Myers Squibb, Chiron, Ortho Biotech, Upjohn, Merck Sharp & Dohme Research Laboratories, Abbot Laboratories, Lilly Research Laboratories, and Evans & Sutherland. The Pierce Immunotoxin Award which recognizes outstanding contributions to immunotoxin research and development, was presented to Drs David FitzGerald, Fatih Uckun, David Eisenberg, and Ira Wool, for their contributions to the immunotoxin field.

  8. Role of ionization fronts in the colliding wind model of planetary nebulae

    International Nuclear Information System (INIS)

    Giuliani, J.L. Jr.

    1981-01-01

    A similarity transformation is used to study the expansion of a planetary nebula which is driven by a fast stellar wind as well as an expanding H II region. The undisturbed gas is taken to be the remnant of a slow, red giant wind. The present analysis improves upon Kwok, Purton, and FitzGerald's colliding wind model for the formation of planetary nebulae since it includes the dynamical influence of ionization fronts, and calculates the variation of velocity and density within the flow

  9. The multifaceted skyrmion

    CERN Document Server

    Rho, Mannque

    2010-01-01

    This is a sequel to the World Scientific volume edited by Gerald E Brown in 1994 entitled ""Selected Papers"", with Commentary, of 'Tony Hilton Royle Skyrme'. There has been a series of impressive developments in the application of the skyrmion structure to wide-ranging physical phenomena. The first volume was mainly focused on the rediscovery of the skyrmion in 1983 in the context of Quantum Chromodynamics (QCD) and on its striking role in nuclear physics. Since 1994, skyrmions have been found to play an even greater role not only in various aspects of particle physics and astrophysics but al

  10. Doing More with Less The New Way to Wealth

    CERN Document Server

    Piasecki, Bruce

    2012-01-01

    "Bruce Piasecki redefines what winning looks like for all of us."-GERALD BRESNICK, Vice President of Environment, Health & Safety and Social Responsibility, Hess "Bruce Piasecki has created a book about discovering and maintaining wealth that, in fact, redefines wealth itself to include much more than mere numbers in a bank account." -JAY PARINI, bestselling author of The Last Station and The Passages of H.M. "Bruce Piasecki is one of the few thinkers really upping the ante for leaders in business and society."-JAMES HOWARD KUNSTLER, bestselling author of The Long Emergency and The Geograph

  11. Analysis of Human Communication during Assembly Tasks.

    Science.gov (United States)

    1986-06-01

    AD-A7l 43 ANALYSIS OF HUMAN COMMUNICATION DURING ASSEMBLY TASKS in1(U) CRNEGIE-MELLO UNIY PITTSBURGH PA ROBOTICS INST UNCLSSIIEDK S BARBER ET AL...ao I Dur~~~~IngAbcbyTs; 7c .S:in i lSAo .0. Analysis of Human Communication During Assembly Tasks K. Suzanne Barber and Gerald J. Agin CMU-RI-TR-86-1...TYPE or REPORT & PE-Rioo CevCZaz Analysis of Human Communication During Assembly Inlterim Tasks I . PERFORMING 00RG. REPORT NUMBER 1. £UT~oOR~e) IL

  12. Psicoterapia interpessoal no tratamento da perturbação depressiva maior

    OpenAIRE

    Lucas, Catarina Oliveira

    2012-01-01

    A terapia interpessoal é um modelo de terapia breve formulado para o tratamento da perturbação depressiva maior, tendo como precursores Gerald Klerman e Mirna Weissman. Esta visa o alívio dos sintomas associados à depressão abordando os problemas interpessoais que os originaram e perpetuam. Esta modalidade de terapia refere as perturbações como resultantes da existência de problemas numa das quatro áreas interpessoais principais: luto, transição de papéis, disputas de papéis interpessoais e d...

  13. Thermal-induced changes on the properties of spin-coated P3HT:C60 thin films for solar cell applications

    CSIR Research Space (South Africa)

    Motaung, DE

    2009-09-01

    Full Text Available on the properties of spin- coated P3HT:C60 thin films for solar cell applications David E. Motaung1, 2, Gerald F. Malgas1,*, Christopher J. Arendse1, Sipho E. Mavundla1, 3 Clive J. Oliphant 1, 2 and Dirk Knoesen2 1National Centre for Nano...-structured Materials, Council for Scientific Industrial Research, P. O. Box 395, Pretoria, 0001, South Africa 2Deparment of Physics, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa 3Deparment of Chemistry, University of the Western...

  14. Whole Exome Analysis of Early Onset Alzheimer’s Disease

    Science.gov (United States)

    2017-04-01

    Alzheimer’s Disease 5a. CONTRACT NUMBER W81XWH-12-1-0013 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Margaret A. Pericak-Vance, Ph.D...Gerald D. Schellenberg, Goldie S . Byrd, Jonathan L. Haines, Margaret A. Pericak-Vance, and the Alzheimer Disease Genetics Consortium. ABCA7 Frameshift...Alzheimer’s & Parkinson’s Diseases (AD/PD), Vienna, Austria, Mar 29-Apr 2, 2017: Cukier HN, Gross SP, Kunkle BW, Rolati S , Hamilton-Nelson KL, Whitehead PL

  15. Los problemas desigualitarios de la Teoría de la Justicia de John Rawls. Una mirada desde Hannah Arendt

    Directory of Open Access Journals (Sweden)

    Benente, Mauro

    2011-12-01

    Full Text Available En el presente artículo desarrollo los principios de justicia esbozados por el filósofo norteamericano John Rawls y presento las críticas que desde perspectivas igualitarias han efectuado Ronald Dworkin, Amartya Sen y Gerald Cohen. Finalmente presento las objeciones que podrían trazarse a la teoría de Rawls desde la obra de Hannah Arendt, críticas que no apuntan a los criterios de distribución de bienes sino al presupuesto de la sociedad entendida como sistema cerrado.

  16. Film and Motivation -- The ’Why We Fight’ Series.

    Science.gov (United States)

    1991-01-07

    great lengths to avoid offending foreign customers."~~oo As explained by Brock Garland, in W&r---Moyi.ee, duing the "late 30s, the film industry shied... film industry found its worst fears realized."alo "On 1 August 1941, two isolationist senators, Gerald P. Nye of North Dakota and Bennett Champ Clark...defense of the film industry , told the Senate, "If you charge that the motion picture industry as a whole and its leading executives as individuals are

  17. A vision of transdisciplinarity laying foundations for a world knowledge dialogue

    CERN Document Server

    Darbellay, Frederic; Billotte, Jerome; Waldvogel, Francis

    2008-01-01

    AcknowledgementsWhere, and Whence ?by André HurstThe Rules of the Game for a Knowledge Dialoguexby Dame Julia HigginsIntroductionFor a World Knowledge Dialogueby Frédéric Darbellay, Moira Cockell, Jérôme Billotte andFrancis WaldvogelChapter 1 Complexity and Neurosciences in Dialogue :Towards a New Theory of the Brain ?1.1 From Brain Dynamics to Consciousness :How Matter Becomes ImaginationAnalysis by Frédéric Darbellay of the presentationby Gerald M. Edelman1.2 Towards a Neuroscience of the Capable Perso

  18. Curves and surfaces for computer-aided geometric design a practical guide

    CERN Document Server

    Farin, Gerald

    1992-01-01

    A leading expert in CAGD, Gerald Farin covers the representation, manipulation, and evaluation of geometric shapes in this the Third Edition of Curves and Surfaces for Computer Aided Geometric Design. The book offers an introduction to the field that emphasizes Bernstein-Bezier methods and presents subjects in an informal, readable style, making this an ideal text for an introductory course at the advanced undergraduate or graduate level.The Third Edition includes a new chapter on Topology, offers new exercises and sections within most chapters, combines the material on Geometric Continuity i

  19. Present at the creation: the founding and formative years of the Association of Academic Health Sciences Libraries.

    Science.gov (United States)

    Jacobson, Susan

    2003-04-01

    The Association of Academic Health Sciences Libraries (AAHSL) was founded in 1978 with the goal of strengthening academic health sciences libraries and increasing their participation nationally in efforts to improve medical education. A primary objective of the organization was to achieve a formal relationship with the Association of American Medical Colleges (AAMC) through membership in the Council of Academic Societies (CAS). Initial steps in establishing AAHSL are examined, including its efforts to join CAS. The author pays tribute to AAHSL's founders, in particular Gerald Oppenheimer, without whose vision and leadership AAHSL would not have been formed.

  20. Field Expedient Armor Modifications to US Armored Vehicles

    Science.gov (United States)

    2006-06-01

    Report on US vs. German Armor,” Exhibit 3, p. 42. 37Ibid., Exhibit 2, p. 38. 38Kenneth W. Estes, Marines Under Armor , The Marine Corps and the...Washington, D.C., 1945), 62. 43Estes, Marines Under Armor , 81. 44Ibid. 45Cameron, “Armor Combat Development 1917-1945,” 17. 46Mayo, The Technical...Marines Under Armor , 53. 72William E. Bennett, Charles W. Fletcher, French G. Lewis, Gerald H. Shea, Rufus J. Cleghorn, James F. Beaver and Thomas

  1. Dogging Cornwall’s 'secret freaks': Béroul on the limits of European orthodoxy

    OpenAIRE

    Simpson, J.

    2013-01-01

    This piece argues that Béroul's version of the Tristan tale can be read as offering a discreetly veiled view of the sexual, ritual and ontological chaos associated with visions of the Celtic West such as figure in Gerald of Wales' History and Topography of Ireland as well as with accounts of heretical orgies found in continental sources such as Caesarius of Heisterbach. Drawing parallels between the poem’s fictional Cornwall and Gerald’s often hyperbolically lurid accounts of the perversions ...

  2. President Ford and both the Soviet and American ASTP crews

    Science.gov (United States)

    1974-01-01

    President Gerald R. Ford removes the Soviet Soyuz spacecraft model from a model set depicting the 1975 Apollo Soyuz Test Project (ASTP), an Earth orbital docking and rendezvous mission with crewmen from the U.S. and USSR. From left to right, Vladamir A. Shatalov, Chief, Cosmonaut training; Valeriy N. Kubasov, ASTP Soviet engineer; Aleksey A. Leonov, ASTP Soviet crew commander; Thomas P. Stafford, commander of the American crew; Donald K. Slayton, American docking module pilot; Vance D. Brand, command module pilot for the American crew. Dr. George M Low, Deputy Administrator for NASA is partially obscured behind President Ford.

  3. Emerging Technologies Program Integration Report. Volume 1. Narrative, Analyses and Assessment

    Science.gov (United States)

    1987-05-04

    James S. (T) 31. GREGG, Dr. Michael C. (T) 61. REDDY, Dr. Raj (T) 2. ATLAS, Dr. David (T) 32. HADDAD, Dr. Genevieve M. 62. REDIKER, Dr. Robert H. 3...Dr. Martin C. 83. WEEKS, Dr. Wilford 6 24. FAETH, Dr. Gerald 54. MUNSON, Mr. John 84. WEINTRAUB, Dr. Daniel 1. (T) 25. FETTERMAN , Dr. Harold 55...T) 2. ATLAS, Dr. David (T) 32. HADDAD, Dr. Genevieve M. 62. REDIKER, Dr. Robert H. 3. BALDESCHWIELER, Dr. John (T) 33. HAMMOND, Dr. George S. 63

  4. Home range dynamics of mountain hare (Lepus timidus in the Swiss Alps

    Directory of Open Access Journals (Sweden)

    Anne-Sophie Genini-Gamboni

    2009-02-01

    Full Text Available Abstract Little is known on the ecology and behaviour of alpine mountain hare (Lepus timidus. Between 1996 and 1997 we analysed by radiotracking the pattern of space use of 8 mountain hares from the Swiss Alps. We estimated home range size using both the kernel density estimator and the minimum convex polygon. We found smaller ranges (38 ha compared to those reported for the species in boreal or arctic habitats, but similar to ranges in Scotland. Hares did not use a centre of major activity (core area and showed high home range overlap, confirming their non-territorial behaviour. Smaller ranges were used during winter compared to the other seasons, whilst no difference in size was found between sexes. Riassunto Dinamica dell'uso dello spazio della lepre bianca (Lepus timidus nelle Alpi Svizzere Le informazioni relative all'ecologia e al comportamento della lepre alpina (Lepus timidus sono ad oggi scarse. In questo studio abbiamo analizzato l'utilizzo dello spazio di una popolazione di lepre bianca sulle Alpi Svizzere. Tra il 1996 e il 1997 sono stati marcati con redio collare 8 individui di lepre alpina. L'home range è stato calcolato utilizzando lo stimatore di densità kernel (KDE ed il metodo del minimo poligono convesso (MCP. L'ampiezza degli home range (38 ha è risultata inferiore a quella riportata per la specie in habitat boreali ed artici. ma simile a quella riscontrata in Scozia. All'interno dell home range non è stato rilevato alcun centro di maggiore attività (core area ed è stata evidenziata una notevole sovrapposizione tra gli stessi, confermando la non territorialità della specie. Le aree frequentate in inverno sono risultate più piccole rispetto alle altre stagioni e non sono state riscontrate differenze tra i sessi.

  5. Overlap of PIV syndrome, VACTERL and Pallister-Hall syndrome: clinical and molecular analysis.

    Science.gov (United States)

    Killoran, C E; Abbott, M; McKusick, V A; Biesecker, L G

    2000-07-01

    The polydactyly, imperforate anus, vertebral anomalies syndrome (PIV, OMIM 174100) was determined as a distinct syndrome by Say and Gerald in 1968 (Say B, Gerald PS. Lancet 1968: 2: 688). We noted that the features of PIV overlap with the VATER association and Pallister-Hall syndrome (PHS, OMIM 146510), which includes polydactyly, (central or postaxial), shortened fingers, hypoplastic nails, renal anomalies, imperforate anus, and hypothalamic hamartoma. Truncation mutations in GL13, a zinc finger transcription factor gene, have been shown to cause PHS. We performed a molecular evaluation on a patient diagnosed with PIV, whose mother, grandfather, and maternal aunt had similar malformations. We sequenced the GLI3 gene in the patient to determine if she had a mutation. The patient was found to have a deletion in nucleotides 2188-2207 causing a frameshift mutation that predicts a truncated protein product of the gene. Later clinical studies demonstrated that the patient also has a hypothalamic hamartoma, a finding in PHS. We concluded that this family had atypical PHS and not PIV. This result has prompted us to re-evaluate the PIV literature to see if PIV is a valid entity. Based on these data and our examination of the literature, we conclude that PIV is not a valid diagnostic entity. We conclude that patients diagnosed with PIV should be reclassified as having VACTERL, or PHS, or another syndrome with overlapping malformations.

  6. Effect of genotype and transport on tonic immobility and heterophil/lymphocyte ratio in two local Italian breeds and Isa Brown hens kept under free-range conditions

    Directory of Open Access Journals (Sweden)

    Michele De Marco

    2013-10-01

    Full Text Available This study was undertaken to investigate the effect of transport and genotype on the welfare and fear response of laying hens through a comparison of three breeds reared in free-range conditions: a commercial strain, the Isa Brown (IBh, and two local chicken breeds, the Bionda Piemontese (BPh and the Bianca di Saluzzo (BSh. After a journey of 67 km (75 min from the farmhouse of origin to the experimental station, ninety hens, divided according to breed, were free-range reared for two months. Body weight (BW, tonic immobility (TI, red and white blood cells, heterophil to lymphocyte (H/L ratio and α1-acid glycoprotein (AGP were assessed at four different sampling times: at the farmhouse of origin (T1, at 1 day (T2, 15 days (T3 and at 2 months (T4 after arrival at the experimental station. No statistical differences were found between the four sampling times for BW, total red and white blood parameters. cells or for AGP. An increase in the H/L ratio (P<0.05 was recorded at time T2 for IBh and BSh, compared to BPh (P<0.05. TI was significantly higher (P<0.05 for the local breeds, BPh and BSh, than for the commercial strain IBh. The results of this study suggest that genetic and adaptive differences can affect both, physiological and ethological parameters.

  7. Assaporare la Tradizione: Cibo, Identità e Senso di Appartenenza nella Letteratura Migrante

    Directory of Open Access Journals (Sweden)

    Vera Horn

    2010-12-01

    Full Text Available Come sostiene Vito Teti, il cibo per l’immigrato è una formadi difesa di un’identità culturale e riflette il bisogno di riconoscersi e diaggregarsi. Il bisogno di trovare senso e posto in un nuovo luogo vengonosegnati da un attaccamento ai cibi perduti, con un senso di sacralità che accompagnail pasto. A partire dalla premessa di Teti, verranno presi in considerazionei romanzi Volevo diventare bianca di Nassera Chohra (1993e Scontro di civiltà per un ascensore a Piazza Vittorio di Amara Lakhous(2006 e i racconti Curry di pollo di Laila Wadia; Salsicce di Igiaba Scego e Il cuoco di Arbëria di Carmine Abate. Tali testi impongono uno sguardo determinante sul cibo come un indice culturale che può rappresentare ocostruire l’identità o determinare l’appartenenza ad una certa comunità, così come rifiutare decisamente qualsiasi contaminazione con la cultura della società ospitante o tentativo di assimilazione o, diversamente, offrire un punto di vista fondato sull’ibridismo; inoltre può favorire la formazione di stereotipi. In questo modo vengono definite prospettive diverse di costruzione dell’identità, sintetizzate da Stuart Hall nel binomio traduzione/tradizione.

  8. Type 2 diabetes in Brazil: epidemiology and management

    Directory of Open Access Journals (Sweden)

    Almeida-Pititto B

    2015-01-01

    Full Text Available Bianca de Almeida-Pititto,1 Monike Lourenço Dias,2 Ana Carolina Franco de Moraes,3 Sandra RG Ferreira,3 Denise Reis Franco,4 Freddy Goldberg Eliaschewitz4,5 1Department of Preventive Medicine, Federal University of São Paulo, São Paulo, Brazil; 2Department of Endocrinology, Federal University of Goiás, Goiânia, Goiás, Brazil; 3Department of Epidemiology, School of Public Health, University of São Paulo, São Paulo, Brazil; 4CPClin Clinical Research Center, 5Albert Einstein Hospital, São Paulo, Brazil Abstract: Type 2 diabetes mellitus (T2DM is one of the most important epidemic diseases in the world this century, and accounts for 90% of cases of diabetes globally. Brazil is one of the most important examples of the alarming picture of T2DM in emergent societies, being the country with the fourth largest number of people with diabetes. The aim of this paper is to review the literature on diabetes in Brazil, specifically looking at the epidemiology and management of T2DM. A literature search was conducted using PubMed and LILACS to identify articles containing information on diabetes in Brazil. Official documents from the Brazilian government, World Health Organization, and International Diabetes Federation were also reviewed. Keywords: type 2 diabetes, Brazil, epidemiology, management

  9. Toward the definition of a carbon budget model: seasonal variation and temperature effect on respiration rate of vegetative and reproductive organs of pistachio trees (Pistacia vera).

    Science.gov (United States)

    Marra, Francesco P; Barone, Ettore; La Mantia, Michele; Caruso, Tiziano

    2009-09-01

    This study, as a preliminary step toward the definition of a carbon budget model for pistachio trees (Pistacia vera L.), aimed at estimating and evaluating the dynamics of respiration of vegetative and reproductive organs of pistachio tree. Trials were performed in 2005 in a commercial orchard located in Sicily (370 m a.s.l.) on five bearing 20-year-old pistachio trees of cv. Bianca grafted onto Pistachio terebinthus L. Growth analyses and respiration measurements were done on vegetative (leaf) and reproductive (infructescence) organs during the entire growing season (April-September) at biweekly intervals. Results suggested that the respiration rates of pistachio reproductive and vegetative organs were related to their developmental stage. Both for leaf and for infructescence, the highest values were observed during the earlier stages of growth corresponding to the phases of most intense organ growth. The sensitivity of respiration activity to temperature changes, measured by Q(10), showed an increase throughout the transition from immature to mature leaves, as well as during fruit development. The data collected were also used to estimate the seasonal carbon loss by respiration activity for a single leaf and a single infructescence. The amount of carbon lost by respiration was affected by short-term temperature patterns, organ developmental stage and tissue function.

  10. Cuerpos-Espacios sonoros: Disonancias en la metrópolis comunicacional

    Directory of Open Access Journals (Sweden)

    Massimo Canevacci

    2008-01-01

    Full Text Available El artículo se concentra en el cambio de la ciudad industrial a la metrópolis comunicacional y en el consecuente cambio de sus habitantes que se adaptan y renuevan a las nuevas condiciones. Este proceso favorece el surgir de un nuevo sujeto (multividuo que cambia su visión del mundo y transforma los escenarios urbanos en lugares fragmentarios y musicales (soundscape. Este cambio es posible sólo gracias a la reapropiación performática de algunos espacios urbanos por parte de artistas y públicos dispuestos a profanar algunos escenarios destinados a fines institucionales o funcionales al desarrollo de la ciudad. En estos espacios el soundscape y el bodyscape interactúan desarrollando nuevos significados y nuevos sentidos en política. En Roma diferentes lugares han sido usadas en años recientes para poner en escena estas performances que se conectan con el cambio urbano y la consecuente modificación de la experiencia sensorial. Tales espacios son utilizados para poner en escena perfomances que resignifican contextos urbanos. En el ensayo se analizarán tres eventos romanos: Disonanze del 2006, La notte bianca del 2006 y la presentación del grupo finlandés Pan Sonic, escogida como una zona de grafitti.

  11. « Le souvenir n’est qu’une maison que l’on porte dans la voix » (Alexandre Amprimoz, Bouquet de signes

    Directory of Open Access Journals (Sweden)

    Sante A. Viselli

    2015-12-01

    Full Text Available Depuis déjà plusieurs années, nous remarquons au Canada la présence d’une littérature unique en son genre, celle des auteurs italo-canadiens. En français, en anglais ou en italien, cette littérature s’est déjà frayé un chemin sûr vers une reconnaissance incontestée au niveau national aussi bien qu’international. Des auteurs tels que Fulvio Caccia, Antonio d’Alfonso, Marco Micone, Carole David-Fioramore, Bianca Zagolin et Alexandre Amprimoz, sont à considérer parmi les lauréats italo-canadiens, porte-parole d’une génération d’érudits cosmopolites et polyglottes. L’œuvre d’Alexandre Amprimoz est, à cet égard, un exemplum des plus marquants d’une littérature multiple et plurielle.

  12. Conversazioni autobiografiche con Albino Sacco-Casamassima

    Directory of Open Access Journals (Sweden)

    Orazio Maria Valastro

    2004-03-01

    Full Text Available Nel 1948 venne Olivetti a Matera. Olivetti venne a Matera con un certo ambasciatore americano che praticamente aveva preparato o stava dando una mano per il piano Marschall, venne a Matera e mi vollero incontrare. Io sono stato chiamato dalla piazza, stavo nella piazza, era il mese di luglio, una cosa di questo genere, e andai in un bar, un bar ad angolo mi ricordo in Via Don Minzioni, dove questo Olivetti mi disse 'ma lei che cosa fa coi sassi?' 'Che cos'è questa storia?' Gli raccontai un po' che cosa facevo io con questi amici, avevamo fatto questo, insomma tutto quello che avevamo fatto nei sassi e che volevamo preparare ancora per presentare a qualcuno un piano di revisionamento dei sassi. Mi ricordo, era la prima volta che avevo visto Adriano Olivetti, ne avevo sentito parlare però non avevo mai visto quest'uomo con gli occhi celesti, minuto, coi capelli bianchi, riccioluto, con una cravatta bianca, cosa che mi fece impressione, una specie di angelo.

  13. Modelling the induction of cell death and chromosome damage by therapeutic protons

    CERN Document Server

    Carante, M P

    2015-01-01

    A two-parameter biophysical model cal led BIANCA (BIophysical ANalysis of Cell death and chromosome Aberrations), which assumes a pivotal role for DNA cluster damage and for “lethal” chromosome aberrations, was applied to calculate cell death and chromosome aberrations for normal and radio-resistant cells along a 62-MeV eye melanoma proton beam. The yield of DNA “Cluster Lesions” and the probability for a chromosome fragment of not being rejoined with any partne r were adjustable parameters. In line with other works, the beam effectiveness at inducing both biological endpoints was found to increase with increasing depth, and high levels of damage were found also beyond the dose fall-off, due to the higher biological effectiveness of low-energy protons. This implies that assuming a constant RBE along the whole SOBP, as is currently done in clinical practice, may be sub-optimal, also implying a possible underestimation of normal tissue damage. Furthermore, the calculations suggested that fo...

  14. Influence of Ripeness and Drying Process on the Polyphenols and Tocopherols of Pistacia vera L.

    Directory of Open Access Journals (Sweden)

    Gabriele Ballistreri

    2009-10-01

    Full Text Available This paper highlights, for the first time, the changes in the phenolics fraction (anthocyanins, flavonoids and stilbenes and tocopherols of unpeeled Pistacia vera L. var. bianca with ripening, and the effect of the sun-drying process. The total polyphenol levels in pistachios, measured as mg of Gallic Acid Equivalent (GAE, were: 201 ± 10.1, 349 ± 18.3 and 184.7 ± 6.2 mg GAE/100 g DM in unripe, ripe and dried ripe samples, respectively. Most phenolics in ripe pistachios were found to be anthocyanins. They increased with ripening, while the sun drying process caused a susbtantial loss. Flavonoids found in all pistachio samples were daidzein, genistein, daidzin, quercetin, eriodictyol, luteolin, genistin and naringenin, which decreased both with ripening and drying. Before the drying process both unripe and ripe pistachios showed a higher content of trans-resveratrol than dried ripe samples. γ-Tocopherol was the major vitamin E isomer found in pistachios. The total content (of α- and γ-tocopherols decreased, both during ripening and during the drying process. These results suggested that unpeeled pistachios can be considered an important source of phenolics, particularly of anthocyanins. Moreover, in order to preserve these healthy characteristics, new and more efficient drying processes should be adopted.

  15. Determination of free amino compounds in betalainic fruits and vegetables by gas chromatography with flame ionization and mass spectrometric detection.

    Science.gov (United States)

    Kugler, Florian; Graneis, Stephan; Schreiter, Pat P-Y; Stintzing, Florian C; Carle, Reinhold

    2006-06-14

    Amino acids and amines are the precursors of betalains. Therefore, the profiles of free amino compounds in juices obtained from cactus pears [Opuntia ficus-indica (L.) Mill. cv. Bianca, cv. Gialla, and cv. Rossa], pitaya fruits [Selenicereus megalanthus (K. Schumann ex Vaupel) Moran, Hylocereus polyrhizus (Weber) Britton & Rose, and Hylocereus undatus (Haworth) Britton & Rose], and in extracts from differently colored Swiss chard [Beta vulgaris L. ssp. cicla (L.) Alef. cv. Bright Lights] petioles and red and yellow beets (B. vulgaris L. ssp. vulgaris var. conditiva Alef. cv. Burpee's Golden) were investigated for the first time. Amino compounds were derivatized with propyl chloroformate. While gas chromatography (GC) with mass spectrometry was used for peak assignment, GC flame ionization detection was applied for quantification of individual compounds. Whereas proline was the major free amino compound of cactus pear and pitaya fruit juices, glutamine dominated in Swiss chard stems and beets, respectively. Interestingly, extremely high concentrations of dopamine were detected in Swiss chard stems and beets. Furthermore, the cleavage of betaxanthins caused by derivatization in alkaline reaction solutions is demonstrated for the first time. Amino acids and amines thus released might increase the actual free amino compound contents of the respective sample. To evaluate the contribution of betaxanthin cleavage to total amino acid and amine concentration, isolated betaxanthins were derivatized according to the "EZ:faast" method prior to quantification of the respective amino compounds released. On a molar basis, betaxanthin contribution to overall amino compound contents was always below 6.4%.

  16. Chemical Composition and Antioxidant Properties of Five White Onion (Allium cepa L. Landraces

    Directory of Open Access Journals (Sweden)

    Loredana Liguori

    2017-01-01

    Full Text Available Five onion landraces belonging to Bianca di Pompei cv., cultivated in Campania region (Italy, were characterized for their main quality parameters. The onion landraces were harvested at the end of the growth cycle corresponding to the ripening time and harvest month, respectively: February, March, April, May, and June. The total content of volatile compounds as well as the sulfur-containing compounds in Aprilatica was significantly (p≤0.05 higher than the other landraces investigated. The nutraceutical feature investigated through the total phenols, phenols profile, and antioxidant activity showed higher values for the samples harvested in spring months. High pungency values ranging from 9 to 14 μmol/g FW were found in all onion landraces investigated as enzymatically (alliinase produced pyruvate (EPY. The organic acids profile (malic, citric, succinic, pyruvic, oxalic, ascorbic, and tartaric acids highlighted malic and citric acids in higher amounts in all landraces. Fructose, glucose, and sucrose were found as soluble sugars and fructose was the most abundant. Generally, the results highlighted the growth temperature influence on the investigated quality parameters.

  17. Reflections: Neurology and The Humanities. The case of the locked house. The finished mystery.

    Science.gov (United States)

    Joynt, Robert J; Kempster, Peter A; Lee, Andrew J

    2014-08-12

    After the death in 2012 of Dr. Robert Joynt, who served Neurology® as CPC Section Editor, an unfinished manuscript was found on his computer. It would have been his sixth Sherlock Holmes pastiche. Intrigued by the story but deflated at the lack of an ending, the editors published the case in the September 10, 2013, issue of Neurology and requested that readers finish it. A panel of editors reviewed over 30 submissions and the top 4 were posted online and on the iPad. Readers voted online, on the iPad, and during the 2014 American Academy of Neurology Annual Meeting in Philadelphia. The winning coauthors are Peter A. Kempster, from Melbourne, and Andrew J. Lees, from London. The runners-up are Anonymous (ending 1), Gerald Honch (ending 2), and Clifton Gooch (ending 4). The editors thank all participants and voters. The rule on page 662 indicates where the winning ending begins.

  18. Bulimia Nervosa/Purging Disorder.

    Science.gov (United States)

    Castillo, Marigold; Weiselberg, Eric

    2017-04-01

    Bulimia nervosa was first described in 1979 by British psychiatrist Gerald Russell as a "chronic phase of anorexia nervosa" in which patients overeat and then use compensatory mechanisms, such as self-induced vomiting, laxatives, or prolonged periods of starvation. The characterization of bulimia nervosa continues to evolve with the introduction of the DSM-5 in 2013. In this article, the epidemiology and risk factors of bulimia nervosa are identified and reviewed, along with the medical complications and psychiatric comorbidities. The evaluation of a patient with suspected bulimia nervosa is addressed, with an emphasis on acquiring a complete and thorough history as well as discovering any comorbidities that are present. Management of the patient involves both medical interventions and behavioral counseling in order to address physical, psychological, and social needs. Lastly, a new diagnosis introduced in the DSM-5, purging disorder, is described and discussed. Copyright © 2017 Mosby, Inc. All rights reserved.

  19. [The function of analogies in natural sciences, also in contrast to metaphors and models].

    Science.gov (United States)

    Hentschel, Klaus

    2010-01-01

    This introduction surveys the various functions of analogies in science, medicine and technology. The focus is on their heuristic importance. The productiveness of analogies is linked to the systematic depth and breadth of the established connections. Various examples are presented from different periods in the history of science, most notably Galileo; such late-Victorian Maxwellians as George Francis FitzGerald and Oliver Lodge; and Heinrich HERTZ and Niels BOHR. These examples are examined in terms of the specific differing temporal ranges of their claimed validities. They serve as evidence or counterevidence for various systematic analyses of analogies as put forward by various philosophers of science, most notably Francis Bacon, John Stuart Mill, Ernst Mach, Harald Høffding, Ernest Nagel, Mary Hesse and Peter Achinstein. The analytic framework for analogies supported here is what the cognitive scientist Dedre Gentner has termed structure-mapping.

  20. MEDIATISASI AGAMA (PEMBINGKAIAN MEDIA KOMPAS.COM TERHADAP ISU PEMERKOSAAN OLEH OKNUM PENGASUH PESANTREN

    Directory of Open Access Journals (Sweden)

    Syihabul Furqon

    2017-12-01

    Full Text Available Framing analysis, methodically is used to dissect discourse impulses that leading to stigma crystallization. Media frames an issue by using language tools and plays a subconscious role in the attitude and understanding of society. Although, basically, every media does framing, but the problem that comes next is when this framing becomes an interest to postulate the lame proposition socially and logically. This research efforts to analyze in narrative about how religion is mediated by Kompas.com, through framing information issue about the Rape by the Board of Pesantren issue in framing analysis of Zhongdang Pan and Gerald M. Kosicki. In conclusion, the Kompas electronic media framing gives rise to a certain tendency toward the negative stigma of pesantren in the public through a narrowing of news content in the media, especially from the interpretation and reporting analysis that revolves around closed syntactic and syntagmatic interactions.

  1. Science and anti-science

    CERN Document Server

    Holton, Gerald

    1997-01-01

    What is good science? What goal--if any--is the proper end of scientific activity? Is there a legitimating authority that scientists mayclaim? Howserious athreat are the anti-science movements? These questions have long been debated but, as Gerald Holton points out, every era must offer its own responses. This book examines these questions not in the abstract but shows their historic roots and the answers emerging from the scientific and political controversies of this century. Employing the case-study method and the concept of scientific thematathat he has pioneered, Holton displays the broad scope of his insight into the workings of science: from the influence of Ernst Mach on twentiethcentury physicists, biologists, psychologists, and other thinkers to the rhetorical strategies used in the work of Albert Einstein, Niels Bohr, and others; from the bickering between Thomas Jefferson and the U.S. Congress over the proper form of federal sponsorship of scientific research to philosophical debates since Oswald...

  2. Strategi Pesan Promosi Kesehatan Cegah Flu Burung

    Directory of Open Access Journals (Sweden)

    Tuti Widiastuti

    2012-12-01

    Full Text Available Avian influenza health disaster has attacked many countries in the world, includes Indonesia. An effort have been done by government through Health Department RI publish health promotion communication on public services advertising (PSA version “Cegah Flu Burung dengan B3K”. In a way to criticize this PSA is used theoretical framework social construction of reality and health promotion. This research use descriptive qualitative method, whereas data is collected with literature review from television PSA, and data analysis technique is used framing analysis from Zhondang Pan and Gerald M. Kosicki. Based on research finding has been found that avian influenza prevention health promotion message not yet “enabling” (ability people to act healthy life, but it only “desiring” (willingness. From this we can say that health promotion still prioritize in giving information, whereas message toward new attitude and behavior changes through learning process still not visible.

  3. Lake Erie and Lake Michigan zebra mussel settlement monitoring and implications for chlorination treatment

    International Nuclear Information System (INIS)

    Demoss, D.; Mendelsberg, J.I.

    1992-01-01

    This paper reports on the 1991 zebra mussel veliger settlement monitoring program undertaken to record and evaluate zebra mussel veliger settlement in Lake Erie and Lake Michigan. Studies by Dr. Gerald Mackie of Canada in 1990 indicated veliger settlement may be occurring primarily during short time periods every season corresponding with warmer water temperatures. Veliger settlement monitoring was performed using a plexiglass sampler apparatus. The samplers were simple in design and consisted of a 20-inch-square plexiglass base panel with thirty-six 1 inch x 3 inch clear plexiglass microscope slides attached. The results of the monitoring program indicate the existence of preferential settlement periods for veligers correlating with sustained lake water temperatures above 70 degrees F. Veliger settlement concentrations in the south basin of Lake Michigan appear to be similar to those in western Lake Erie

  4. Peer review of RELAP5/MOD3 documentation

    International Nuclear Information System (INIS)

    Craddick, W.G.

    1993-01-01

    A peer review was performed on a portion of the documentation of the RELAP5/MOD3 computer code. The review was performed in two phases. The first phase was a review of Volume 3, Developmental Assessment problems, and Volume 4, Models and Correlations. The reviewers for this phase were Dr. Peter Griffith, Dr. Yassin Hassan, Dr. Gerald S. Lellouche, Dr. Marino di Marzo and Mr. Mark Wendel. The reviewers recommended a number of improvements, including using a frozen version of the code for assessment guided by a validation plan, better justification for flow regime maps and extension of models beyond their data base. The second phase was a review of Volume 6, Quality Assurance of Numerical Techniques in RELAP5/MOD3. The reviewers for the second phase were Mr. Mark Wendel and Dr. Paul T. Williams. Recommendations included correction of numerous grammatical and typographical errors and better justification for the use of Lax's Equivalence Theorem

  5. Milnacipran: recent findings in depression

    Directory of Open Access Journals (Sweden)

    Guest editors: Stuart Montgomery (London

    2010-08-01

    Full Text Available EDITORIAL FOREWORDPage 1   Milnacipran: recent findings in depression Stuart Montgomery (London, UK and Mike Briley (Castres, France REVIEWSPage 3   Suicidality: risk factors and the effects of antidepressants. The example of parallel reduction of suicidality and other depressive symptoms during treatment with the SNRI, milnacipran Philippe Courtet (Montpellier, FrancePage 9   Treatment of patients with comorbid depression and diabetes with metformin and milnacipran Peter Hofmann (Graz, AustriaPage 17  Antidepressant therapy with milnacipran and venlafaxine Lucilla Mansuy (Toulouse, FrancePage 23  Milnacipran: a unique antidepressant? Siegfried Kasper and Gerald Pail (Vienna, Austria This supplement is based on a symposium that took place at the 9th International Forum on Mood and Anxiety in Monte Carlo in November 2009 and is supported by an unconditional education grant from Pierre Fabre Médicament.

  6. Energy accounting of materials, products, processes and services. [Ten papers

    Energy Technology Data Exchange (ETDEWEB)

    Verbraeck, A [ed.

    1976-01-01

    Ten papers were presented, namely: Units in Energy Accounting--How Are They Defined, How Are They Measured, by Dr. Malcolm Slesser; Economics of Energy Analysis, by Dr. Thomas Veach Long II; Energy Considerations in Synthetic and Natural Fibers, by Mr. A. H. Woodhead; Energy Accounting in Food Products, by Mr. Gerald Leach; Energy Analysis of Transportation Systems, by Dr. E. J. Tuininga; Energy Accounting of Packaging Materials for Liquids and Their Transport viz Bottles and Pipes, by Mr. A. Bolzinger; Energy Accounting of Steel, by Dr. A. Decker; Energy Accounting of Aluminium, by Dr. D. Altenpohl, T. S. Daugherty, and W. Blum; Energy Requirement of Some Energy Sources, by Dr. P. F. Chapman and Dr. D. F. Hemming; Energy Analysis of Materials and Structures in the Building Industry, by Professor Dr. P. C. Kreijger. A panel discussion in response to a large number of questions was chaired by Professor Dr. W. van Gool. (MCW)

  7. JGR special issue on Deep Earthquakes

    Science.gov (United States)

    The editor and associate editors of the Journal of Geophysical Research—Solid Earth and Planets invite the submission of manuscripts for a special issue on the topic “Deep- and Intermediate-Focus Earthquakes, Phase Transitions, and the Mechanics of Deep Subduction.”Manuscripts should be submitted to JGR Editor Gerald Schubert (Department of Earth and Space Sciences, University of California, Los Angeles, Los Angeles, CA 90024) before July 1, 1986, in accordance with the usual rules for manuscript submission. Submitted papers will undergo the normal JGR review procedure. For more information, contact either Schubert or the special guest associate editor, Cliff Frohlich (Institute for Geophysics, University of Texas at Austin, 4920 North IH-35, Austin, TX 78751; telephone: 512-451-6223).

  8. Philosophy of physics space and time

    CERN Document Server

    Maudlin, Tim

    2012-01-01

    This concise book introduces nonphysicists to the core philosophical issues surrounding the nature and structure of space and time, and is also an ideal resource for physicists interested in the conceptual foundations of space-time theory. Tim Maudlin's broad historical overview examines Aristotelian and Newtonian accounts of space and time, and traces how Galileo's conceptions of relativity and space-time led to Einstein's special and general theories of relativity. Maudlin explains special relativity using a geometrical approach, emphasizing intrinsic space-time structure rather than coordinate systems or reference frames. He gives readers enough detail about special relativity to solve concrete physical problems while presenting general relativity in a more qualitative way, with an informative discussion of the geometrization of gravity, the bending of light, and black holes. Additional topics include the Twins Paradox, the physical aspects of the Lorentz-FitzGerald contraction, the constancy of the speed...

  9. Observing comets

    CERN Document Server

    James, Nick

    2003-01-01

    Since comet Shoemaker-Levy collided with the planet Jupiter with stupendous force in 1994 there has been an upsurge of amateur interest in comets Most comets are first discovered by amateur astronomers because there are so many amateurs looking for them, and techniques and instruments have improved dramatically in the past few years After a short but detailed introduction to the comets themselves Nick James and Gerald North describe comet hunting, photographing and imaging comets, and digital image processing The use of computers for orbital calculations and even helping to discover new comets is given a full chapter, as are advanced techniques including comet photometry and spectroscopy This comprehensive book has an accompanying CD-ROM and is at once a "primer" for comet hunters and a reference text for more advanced amateur astronomers

  10. AHP 4: na53 mʑi53 Tibetan Songs, Engagement Chants, and Flute Music

    Directory of Open Access Journals (Sweden)

    LIBU LAKHI (LI JIANFU 李建富, DAWA TENZIN ཟླ་བ་བསྟན་འཛིན།

    2010-06-01

    Full Text Available The present study is a straightforward, pragmatic attempt to document the particulars of na53 mi53 song and musical traditions comprising the local 'performance-scape'. The primary researcher, Libu Lakhi, is a native of the community who was trained in a specialized mode of auto-ethnography developed by Charles Kevin Stuart and Gerald Roche at Qinghai Normal University 青海师范大学, Xining City 西宁市, Qinghai Province 青海省. Drawing on ethnomusicology, socio-linguistics, and the 'performance' school of folkloristics, the model is intended to enable local peoples to document and display their own traditions in a form available to scholars and interested persons on a global scale.

  11. 1st International Industrial Symposium on the Supercollider

    CERN Document Server

    IISSC; Supercollider 1

    1989-01-01

    IISSC '89 was a tremendous success. A total of 635 people attended this educational forum which was dedicated to further the understanding of the design, construction and operation of the Superconducting Supercollider (SSC). A total of 110 presentations and addresses were given. The topics discussed covered .all aspects of the SSC including: Magnet Technology Cryogenics Conventional Facilities Technical Systems Detectors Related Accelerator Technology Superconducting Wire/Cable ApproXimately 38% of the presentations addressed superconducting magnet technology, 16% were devoted to detector technology, 10% addressed superconducting wire/ cable, and the balance was equally split between the remaining topics. A special award was presented to Professor M. Tigner for his meritorious contribution to the Superconducting Supercollider (SSC). The award was presented on behalf of the IISSC Board of Directors. Keynote speakers included: Gerald 'Bachy, CERN Joe Barton, Representative from Texas, 6th Disctrict Ed...

  12. Use of retractors and explainers in charismatic rhetoric: the case of four American presidents

    Directory of Open Access Journals (Sweden)

    Iaroslav Kovalchuk

    2013-05-01

    Full Text Available This study examines the use of retractors and explainers in prepared political speeches of American charismatic presidents. It is based upon the results of psychological analysis of 24 speeches of John F. Kennedy, Ronald Reagan, Barack Obama, and Gerald Ford. The research shows that certain differences may be found in the use of explainers and retractors not along the axis “Charismatic versus Non-Charismatic Presidents”, but with regard to their party affiliation. Rhetoric of Democratic presidents (Kennedy, Obama is characterized by a more explanatory communication style than of Republican ones (Reagan, Ford, which results in respective differences in the use of explainers. As for the retractors, all the four presidents under study tend to use the category moderately, which reveals them as emotionally controlled individuals, able to reconsider their decisions if necessary.

  13. Fotometría y polarimetría de Lynga 1

    Science.gov (United States)

    Brusasco, M. A.; Baume, G.; Vázquez, R. A.

    Se presentan los resultados de las observaciones fotométricas CCD-UBVRI hasta magnitud aproximadamente V = 18 y polarimétricas hasta V = 13 en la zona del cúmulo abierto Lynga 1. El mismo se halla en una dirección cercana a un remanente de supernova y fue estudiado previamente por Peterson y FitzGerald (1988) mediante fotometría fotoeléctrica. Se ha redeterminado el enrojecimiento, la distancia y la edad de dicho objeto. Se han hallado además los valores de las pendientes de las funciones de luminosidad y de masa comparándoselas con las de otros cúmulos de edades similares.

  14. Fotometría y polarimetría de Trumpler 21

    Science.gov (United States)

    Giorgi, E.; Baume, G.; Vázquez, R. A.

    Se presentan los resultados de las observaciones fotométricas CCD-UBVI hasta aproximadamente magnitud V = 19 y polarimétricas UBVRI hasta V =13 en la región del cúmulo abierto Trumpler 21. El mismo se halla en una dirección cercana al remanente de supernova G307.6-0.3 y fue estudiado previamente por Moffat y Vogt (1973) y por Peterson y FitzGerald (1988) mediante fotometría fotoeléctrica de las estrellas más brillantes. Se ha redeterminado el enrojecimiento, la distancia y la edad de dicho objeto. Se han hallado además los valores de las pendientes de las funciones de luminosidad y de masa comparandoselas con las de otros cúmulos de edades similares.

  15. Scientific Astrophotography How Amateurs Can Generate and Use Professional Imaging Data

    CERN Document Server

    Hubbell, Gerald R

    2013-01-01

    Scientific Astrophotography is a work for those amateur astronomers looking for new challenges, once they have mastered visual observing and the basic imaging of various astronomical objects. It is a wonderful reference for scientifically-inclined observers who want to learn the fundamentals of astrophotography with a firm emphasis on the discipline of scientific imaging. This book is a wealth of information and a distillation of ideas presented by a diverse set of sources and based on the most recent techniques, equipment, and data available. It also includes numerous exercises for the reader, to maximize the success and minimize the frustration inherent in the pursuit of this specific craft. Scientific Astrophotography is perfect for any amateur astronomer who wants to go beyond just the process of making beautiful images and actually contribute to the science of astronomy! "...Gerald Hubbell's new book, Scientific Astrophotography, is the perfect companion for anyone dipping their toe into the digital imag...

  16. "Kids not rights, is their craving": sex education, gay rights, and the threat of gay teachers.

    Science.gov (United States)

    Graydon, Michael

    2011-08-01

    In July 1977, the Ontario Humans Rights Commission recommended adding sexual orientation to the Code. This move was generally supported but Toronto newspapers and evangelists sought assurances that school boards could still dismiss homosexual teachers. They demanded children be shielded from gay teachers, who they accused of sexual predation. I historically link this to a reenergized fear of homosexuals which emerged during Toronto sex education debates in the 1970s. Later, influenced by Anita Bryant's Save the Children crusade, Toronto newspapers and evangelists argued gay teachers were the dangerous effect of gay rights. After the 1977 murder of Emanuel Jaques and the publication of Gerald Hannon's "Men Loving Boys, Loving Men" article, anti-gay sentiment in Toronto exploded, temporarily halting the progress of gay rights.

  17. Assimilating American Indians in James Fenimore Cooper’s Novels?

    Directory of Open Access Journals (Sweden)

    Peprník Michal

    2016-07-01

    Full Text Available The article employs critical concepts from sociology and anthropology to examine the stereotype of the Vanishing Indian and disclose its contradictory character. The article argues that in James Fenimore Cooper’s late novels from the 1840s a type of American Indian appears who can be regarded as a Vanishing Indian in many respects as he displays some slight degree of assimilation but at the same time he can be found to reveal a surprising amount of resistance to the process of vanishing and marginalization. His peculiar mode of survival and his mode of living demonstrate a certain degree of acculturation, which comes close to Gerald Vizenor’s survivance and for which I propose a term critical integration. I base my study on Susquesus (alias Trackless, Cooper’s less well-known character from The Littlepage Manuscripts, a three-book family saga.

  18. The Salt II Treaty

    International Nuclear Information System (INIS)

    Caldwell, D.

    1991-01-01

    The first strategic arms limitation talks resulted in two agreements: the Anti-Ballistic Missile Treaty and the Interim Agreement to Limit Strategic Offensive Arms. Senator Henry M. (Scoop) Jackson (D-Wa.) was concerned about the numerical advantage granted to the USSR by the Latter agreement and proposed an amendment that would prohibit future negotiators from granting the Soviet Union similar terms. This paper discusses the second round of SALT negotiations which opened in November 1972 and continued under presidents Richard M. Nixon, Gerald Ford, and Jimmy Carter. As the negotiators met, U.S. and Soviet scientists and engineers continued their work to develop new nuclear weapons and launchers. Particularly problematic were modern, large ballistic missiles, cruise missiles, and the Soviet Backfire bomber

  19. Assessing the Resilience of Global Sea Routes

    Science.gov (United States)

    2012-06-01

    Salmeron Thesis Advisor Gerald G. Brown Second Reader Robert F. Dell Chair, Department of Operations Research iv THIS PAGE...Japan 730.10 639.10 1.14 Korea South 464.30 422.40 1.10 Malaysia 197.00 152.60 1.29 Netherlands 486.70 429.50 1.13 Norway 132.70 74.30 1.79 Pakistan...9.1%, Singapore 8.7%, South Korea 8%, India 6.3%, Malaysia 5.9% Italy Germany 13.2%, France 11.7%, Spain 5.9%, U.S. 5.8%, U.K. 5.4%, Switzerland 4.6

  20. A preliminary report of geochemical investigations in the Blackbird District

    Science.gov (United States)

    Canney, F.C.; Hawkes, H.E.; Richmond, G.M.; Vhay, J. S.

    1953-01-01

    This paper reviews an experimental geochemical prospecting survey in the Blackbird cobalt-copper mining district. The district is in east-central Idaho, about 20 miles west-southwest of Salmon. The area is one of deeply weathered nearly flat-topped upland surfaces cut by steep-walled valleys which are tributary to the canyon of Panther Creek. Most of the area has a relatively heavy vegetative cover, and outcrops are scarce except on the sides of the steeper valleys* Because of the importance of the surficial deposits and soils and the physiographic history of the region on the interpretation of the geochemical data, a separate chapter on this subject by Gerald H. Richmond follows the following brief description of the geology of the district.

  1. Framing Pemberitaan Citra Politik Capres 2014 di Harian Solopos

    Directory of Open Access Journals (Sweden)

    Puji Widi Astutik

    2016-03-01

    Full Text Available The article tries to find out the construction of the image formation in the daily Solopos 2014 candidates. Basic theoretically in this paper uses descriptive analysis method with a form of text analysis models Zhongdang Pan and Gerald M. Kosicki through four units of analysis, syntax, script, thematic, and Rhetorical. Framing analysis is used to see how the image formation through the political news in the Daily Solopos 2014 candidates. Through this analysis can be found that the construction of a shadow image (mirror image performed on the outlook for both candidates figure formed by the track record of each kandindat. Joko Widodo figure in the frame with the figure of the fight for the people and work for the people, while the figure Prabowo has a bad track record as it is considered to participate in the abduction tragedy in which 98 activists at that time as a military Prabowo.

  2. The psychology of computer programming

    CERN Document Server

    Weinberg, Gerald Marvin

    1998-01-01

    This landmark 1971 classic is reprinted with a new preface, chapter-by-chapter commentary, and straight-from-the-heart observations on topics that affect the professional life of programmers. Long regarded as one of the first books to pioneer a people-oriented approach to computing, The Psychology of Computer Programming endures as a penetrating analysis of the intelligence, skill, teamwork, and problem-solving power of the computer programmer. Finding the chapters strikingly relevant to today's issues in programming, Gerald M. Weinberg adds new insights and highlights the similarities and differences between now and then. Using a conversational style that invites the reader to join him, Weinberg reunites with some of his most insightful writings on the human side of software engineering. Topics include egoless programming, intelligence, psychological measurement, personality factors, motivation, training, social problems on large projects, problem-solving ability, programming language design, team formati...

  3. The Geneva Protocol of 1925

    International Nuclear Information System (INIS)

    Mc Elroy, R.J.

    1991-01-01

    This paper reports that when President Gerald Ford signed the instruments of ratification for the Geneva Protocol of 1925 on January 22, 1975, a tortured, half-century-long chapter in U.S. arms control policy was brought to a close. Fifty years earlier, at the Geneva Conference for the Control of the International Trade in Arms, Munitions and Implements of War, the United States had played a key role in drafting and reaching agreement on the Protocol for the Prohibition of the Use in War of Asphyxiating, Poisonous or Other Gases and of Bacteriological Methods of Warfare. The protocol, signed by thirty nations, including the United States, on June 17, 1925, prohibits the use in war of asphyxiating, poisonous or other gases, and of all analogous liquids, materials or devices as well as the use of bacteriological methods of warfare

  4. Quantum mechanics in a nutshell

    CERN Document Server

    Mahan, Gerald D

    2009-01-01

    Covering the fundamentals as well as many special topics of current interest, this is the most concise, up-to-date, and accessible graduate-level textbook on quantum mechanics available. Written by Gerald Mahan, a distinguished research physicist and author of an acclaimed textbook on many-particle physics, Quantum Mechanics in a Nutshell is the distillation of many years' teaching experience. Emphasizing the use of quantum mechanics to describe actual quantum systems such as atoms and solids, and rich with interesting applications, the book proceeds from solving for the properties of a single particle in potential; to solving for two particles (the helium atom); to addressing many-particle systems. Applications include electron gas, magnetism, and Bose-Einstein Condensation; examples are carefully chosen and worked; and each chapter has numerous homework problems, many of them original

  5. Nuclear policy

    International Nuclear Information System (INIS)

    Ford, G.R.

    1976-01-01

    Then-President Gerald Ford outlines the potential benefits of nuclear power as opposed to the danger of proliferation. He points out that not all nations have the same interest or views toward nuclear energy; but also he says that if a choice must be made, nonproliferation objectives must take precedence over economic and energy benefits. It is pointed out that the management of nuclear energy can be only partial and temporary by technical measures, and that full management can result only if nations realistically face the task prepared to forego preconceived short-term advantages in favor of long-term gains. Coordination of the policies of all nations toward the common goal of nonproliferation is predicted to lead to success

  6. Influence des déformations tectoniques sur les caractéristiques pétrophysiques matricielles des réservoirs calcaires Influence of Tectonic Deformation on the Petrophysical Matrix Properties of Limestone Reservoirs

    Directory of Open Access Journals (Sweden)

    Trémolières P.

    2006-11-01

    Full Text Available Cet article présente les principaux résultats d'une étude menée en commun par l'Institut Français du Pétrole (IFP et la Société Nationale Elf Aquitaine (Production (SNEA (P, étude qui avait pour but de rechercher l'influence des contraintes tectoniques sur les propriétés pétrophysiques matricielles des réservoirs calcaires. Ces travaux, ayant porté principalement surle Burdigalien des Alpilles (Provence et accessoirement sur le Turonien de Mareuil (Aquitaine et la « Scaglia bianca » du Monte Conero (Ancàne-Itatie, ont permis de mettre en évidence - des variations importantes de la porosité et de la perméabilité en fonction de la position structurale du matériau et, à plus petite échelle, de la courbure des couches; - un double processus de la réduction des porosité et perméabilité : soit par tassement mécanique, soit par cristallisation dans les pores d'une calcite provenant probablement d'une dissolution le long de joints stylolithiques d'origine tectonique. On montre enfin qu'en certaines zones particulières (dans les périclinaux ou à l'aplomb d'accidents profonds jouant en faille inverse les effets des contraintes tectoniques sur les qualités matricielles peuvent être très importants et survenir avant la structuration des couches par plissement. This article describes the main results of a joint Institut Français du Pétrole (IFP-Société Nationale Elf Aquitaine (Production (SNEA (P research project on the influence of tectonic stresses on thé petrophysical matrix properties of limestone reservoirs. Research mainly concentrated on the Burdigalien from the Alpilles mountains in ihe Provence région and accessorily on the Turonian from Mareuil in the Aquitaine region and Scaglia Bianca from Monte Conero in Anconia, Italy. The following findings were made: - considerable variations in porosity and permeability can be found, depending on the structural position of the material and, on a smaller scale, on the

  7. 3D-TRANS-2003, Workshop on Common Tools and Interfaces for Radiation Transport Codes

    International Nuclear Information System (INIS)

    2004-01-01

    Description: Contents proceedings of Workshop on Common Tools and Interfaces for Deterministic Radiation Transport, for Monte Carlo and Hybrid Codes with a proposal to develop the following: GERALD - A General Environment for Radiation Analysis and Design. GERALD intends to create a unifying software environment where the user can define, solve and analyse a nuclear radiation transport problem using available numerical tools seamlessly. This environment will serve many purposes: teaching, research, industrial needs. It will also help to preserve the existing analytical and numerical knowledge base. This could represent a significant step towards solving the legacy problem. This activity should contribute to attracting young engineers to nuclear science and engineering and contribute to competence and knowledge preservation and management. This proposal was made at the on Workshop on C ommon Tools and Interfaces for Deterministic Radiation Transport, for Monte Carlo and Hybrid Codes , held from 25-26 September 2003 in connection with the conference SNA-2003. A first success with the development of such tools was achieved with the BOT3P2.0 and 3.0 codes providing an easy procedure and mechanism for defining and displaying 3D geometries and materials both in the form of refineable meshes for deterministic codes or Monte Carlo geometries consistent with deterministic models. Advanced SUSD: Improved tools for Sensitivity/Uncertainty Analysis. The development of tools for the analysis and estimation of sensitivities and uncertainties in calculations, or their propagation through complex computational schemes, in the field of neutronics, thermal hydraulics and also thermo-mechanics is of increasing importance for research and engineering applications. These tools allow establishing better margins for engineering designs and for the safe operation of nuclear facilities. Such tools are not sufficiently developed, but their need is increasingly evident in many activities

  8. Optimal management of nail disease in patients with psoriasis

    Directory of Open Access Journals (Sweden)

    Piraccini BM

    2015-01-01

    Full Text Available Bianca Maria Piraccini, Michela Starace Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy Abstract: Psoriasis is a common skin disease, with nail involvement in approximately 80% of patients. Nail psoriasis is often associated with psoriatic arthropathy. Involvement of the nails does not always have relationship with the type, gravity, extension, or duration of skin psoriasis. Nail psoriasis can occur at any age and all parts of the nails and the surrounding structures can be affected. Two clinical patterns of nail manifestations have been seen due to psoriasis: nail matrix involvement or nail bed involvement. In the first case, irregular and deep pitting, red spots of the lunula, crumbling, and leukonychia are seen; in the second case, salmon patches, onycholysis with erythematous border, subungual hyperkeratosis, and splinter hemorrhages are observed. These clinical features are more visible in fingernails than in toenails, where nail abnormalities are not diagnostic and are usually clinically indistinguishable from other conditions, especially onychomycosis. Nail psoriasis causes, above all, psychosocial and aesthetic problems, but many patients often complain about functional damage. Diagnosis of nail psoriasis is clinical and histopathology is necessary only in selected cases. Nail psoriasis has an unpredictable course but, in most cases, the disease is chronic and complete remissions are uncommon. Sun exposure does not usually improve and may even worsen nail psoriasis. There are no curative treatments. Treatment of nail psoriasis includes different types of medications, from topical therapy to systemic therapy, according to the severity and extension of the disease. Moreover, we should not underestimate the use of biological agents and new therapy with lasers or iontophoresis. This review offers an investigation of the different treatment options for nail

  9. Looking inside the Panarea Island (Aeolian Archipelago, Italy by gravity and magnetic data

    Directory of Open Access Journals (Sweden)

    F. Greco

    2008-06-01

    Full Text Available In this paper we show and discuss the results of gravity and magnetic surveys of Panarea Island and its archipelago. The most recent volcanic manifestation occurred in November 2002 with a shallow submarine gas eruption between the islets of Dattilo, Panarelli, Lisca Bianca, Bottaro and Lisca Nera. Currently, the activity of Panarea is monitored through a multidisciplinary study under the umbrella of the Italian Department of Civil Protection with the goal of defining the hazard of this area. With this aim, in May 2006 the first gravity and magnetic surveys of Panarea Island and its archipelago were performed. The offshore magnetic data were obtained using a marine magnetometer, a Geometrics G880, from the Istituto Idrografico dell Marina (IIM. Onshore and offshore magnetic data were integrated into an unique dataset for complete magnetic coverage of the study area. By using two micro-gravimeters (LaCoste & Romberg, gravity data were collected along tracks every 250 meters. The gravity dataset was processed using the standard method. A Bouguer reduction was applied to the free-air gravity dataset using a detailed digital elevation model of the island and the neighbouring sea after evaluation of the optimal Bouguer density to reduce the topographic effect. The result is a Bouguer anomaly map that shows lateral variations in density distribution and the relationships between the shallow volcanic/crustal features and tectonic lineaments. This evidence is also highlighted by the magnetic pattern, which suggests the importance of the youngest volcanic deposits with respect to the magnetic features of the island.

  10. Assessment of Genetic Diversity in Opuntia spp. Portuguese Populations Using SSR Molecular Markers

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    Carlos M. G. Reis

    2018-04-01

    Full Text Available The Opuntia spp., most likely few individuals, were introduced in the Iberian Peninsula in the beginning of the 16th century, after the discovery of America, spreading afterwards throughout the Mediterranean basin. We analysed, for the first time, the genetic diversity in a set of 19 Portuguese Opuntia spp. populations from the species O. ficus-indica, O. elata, O. dillenii and O. robusta using nuclear microsatellite (nuSSR markers. The Italian cultivars ‘Bianca’, ‘Gialla’ and ‘Rossa’ were included in the study for comparison purposes. The nuSSR amplifications produced from five to 16 alleles, with an average of 9.2 alleles per primer pair, and average polymorphism information content of 0.71. The estimated Dice coefficient among populations varied from 0.26 to 1.0, indicating high interspecific genetic diversity but low genetic diversity at the intraspecific level. The hierarchical clustering analysis revealed four major groups that clearly separated the four Opuntia species. Among the O. ficus-indica populations, two sub-clusters were found, one including the white pulp fruits (with cv. Bianca and the other with the orange pulp ones and including the cv. Gialla, the cv. Rossa, and one pale yellow pulp population. No genetic differences were found between the inermis form, O. ficus-indica f. ficus-indica, and the rewilded spiny one, O. ficus-indica f. amyclaea. The dendrogram indicated that the clustering pattern was unrelated to geographical origin. The results revealed a low level of genetic diversity among the Portuguese populations of O. ficus-indica.

  11. Caracterización de cultivares de duraznero (Prunus persica (L. Batsch. por resistencia a heladas

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    Javier Emilio Chaar

    2015-07-01

    Full Text Available Las heladas primaverales son una de las principales limitantes de la producción de frutales de clima templado. Dentro de una misma especie existe variabilidad en resistencia frente al daño en órganos florales ocasionado por temperaturas bajo cero durante la salida del reposo invernal. En cinco cultivares de duraznero (Prunus persica (L. Batsch. y uno de nectarino se evaluó el daño ocasionado por heladas y se determinaron la fecha de plena floración y la densidad de floración. Adicionalmente se determinó la temperatura letal media (TL50 de las yemas florales en el estado de flor abierta, mediante descensos térmicos controlados en laboratorio. Los cultivares (cv de duraznero Maria Bianca y Summer Pearl presentaron las mayores densidades de flores sanas por cm de ramo, luego de la ocurrencia de temperaturas bajo cero en campo. La resistencia a heladas en campo se relacionó principalmente con la elevada densidad de floración, en combinación, en algunos casos, con floración tardía. La floración tardía por sí sola no resultó una característica de resistencia; por tanto, para la elección de cultivares de duraznero con menor riesgo de daño por temperaturas bajo cero es importante tener en cuenta más de una variable relacionada con los órganos reproductivos

  12. Edificio propiedad de la «Home Insurance»

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    Wimberly & Cook, Arquitectos

    1963-10-01

    Full Text Available On a 5,564 m2 site, in Honolulu, this buildings has an actual ground area of 4,645 m2. It has five storeys. The first three floors and part of the fourth floor —which contains the cafeteria and lecture room— are occupied by the offices and other installations of the «Home Insurance» in Hawaii. The remaining space is let out. The project has also parking space for 100 cars. The design of the general layout has been planned thinking of possible extensions and adaptations to new functional requirements. Aluminium Venetian blinds have been fitted, and these have proved to be a successful protection against intense sunlight, since they prevent the light to shine directly on the office desks, they reduce lateral luminosity, and insure a satisfactory level of illumination. The entrance hall has a fine mural, designed by Gerald Allison and made by Hawaii Ceramics.Ha sido construido en Honolulú, sobre un solar de 5.564 ms2, de los que la edificación ocupa una superficie de 4.645 metros cuadrados. Consta de cinco plantas: la planta baja, primera, segunda y parte de la cuarta—en la que se distribuyen la cafetería y la sala de conferencias—, las utiliza para sus oficinas y dependencias principales, en Hawai, la «Home Insurance»; la tercera y resto de la cuarta se destinan a alquiler. Dispone también de un gran aparcamiento con capacidad para 100 coches. Todas sus instalaciones han sido proyectadas, previendo la fácil realización de futuras ampliaciones y adaptaciones a nuevas necesidades. La celosía de aluminio ha demostrado ser buena solución para la protección contra el sol, pues impide que los rayos solares incidan directamente sobre las mesas de trabajo, reduce el brillo lateral, y asegura una buena visibilidad. Como aportación de las Artes Plásticas existe un mural en el vestíbulo de entrada, diseñado por Gerald Allison y realizado por Cerámicas Hawai.

  13. 教育制度中的社會正義理論分析 ― 多元觀點與比較基礎建構 A Study of Social Justice Theories in Educational Systems: Multiple-Perspectives and Construction of Comparative Foundation

    Directory of Open Access Journals (Sweden)

    王俊斌 Chun-Ping, Wang

    2016-12-01

    Full Text Available 有關社會正義與教育公平議題之研究,當代呈現資源論轉向或能力取向理論之「後羅爾斯」思潮。在此脈絡下,本研究之目的如下:首先,對比「經濟正義」與「司法正義」,藉此說明「教育正義」內涵之特殊性及其複雜性;其次,分析英、美與華人社會「教育正義」理念及其制度運作之社會脈絡,並以此反映「教育正義」的「同語歧義」現象;第三,為解決各國教育制度之正義觀點之可比較性基礎,本研究將考察當代政治哲學研究的「後羅爾轉向」,諸如Thomas Pogge、Gerald A. Cohen、Iris M. Young、Nancy Fraser、Amartya Sen、Martha Nussbaum等學者見解,企圖以此建立多元角度之比較視野;最後,將依據多元「正義」觀點之比較視野,建構各國教育制度之社會正義比較的參照架構。 Within the context of capitalist globalization, almost all justice theories are inevitably influenced by John Rawls’s notions of “justice as fairness” or political liberalism. Recently, a number of frontier studies or critical revisions have appeared, authored by such people as Thomas Pogge, Gerald A. Cohen, Iris M. Young, Nancy Fraser, Amartya Sen, and Matha Nussbaum, which have merged to form a contemporary “Post-Rawlsian Turn”. The main purposes of this article are as follows: firstly, to analyze different theoretical claims relating to “educational justice” and assess their feasibility; secondly, to inquire into the reasons why particular educational justice discourses are raised within certain social contexts; thirdly, to discuss different perspectives of “social justice” and elaborate on their educational implications; finally, to compare different orientations towards “justice” and attempt to provide a reasonable basis for the comparative study of social justice theories in educational systems.

  14. Does knowledge on diabetes management influence glycemic control? A nationwide study in patients with type 1 diabetes in Brazil

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    Gomes MB

    2018-01-01

    Full Text Available Marilia Brito Gomes,1 Deborah Conte Santos,1 Marcela H Pizarro,1 Bianca Senger V Barros,1 Laura G Nunes de Melo,2 Carlos A Negrato3 1Department of Internal Medicine, Diabetes Unit, State University Hospital of Rio de Janeiro, 2Department of Ophthalmology, State University of Rio de Janeiro, Rio de Janeiro, 3Department of Internal Medicine, Bauru’s Diabetics Association, Bauru, São Paulo, Brazil Objective: The purpose of this study is to establish demographic and clinical data associated with the knowledge on diabetes management and its influence on glycemic control in patients with type 1 diabetes.Methods: This was a retrospective, observational, multicenter study conducted with 1,760 patients between August 2011 and August 2014 in 10 cities of Brazil.Results: Overall, 1,190 (67.6% patients knew what glycated hemoglobin (HbA1c means. These patients were older, had longer disease duration, longer follow-up in each center, reported lower frequency of self-reported hypoglycemia, and were more frequently Caucasians and at glycemic goal. Multivariate analysis showed that knowledge on what HbA1c means was related to more years of school attendance, self-reported ethnicity (Caucasians, severe hypoglycemia, economic status, follow-up time in each center, and participation on diabetes educational programs. Good glycemic control was related to older age, more years of school attendance, higher frequency of daily self-monitoring of blood glucose, higher adherence to diet, and knowledge on what HbA1c means.Conclusion: Patients with a knowledge on what HbA1c means had a better chance of reaching an adequate glycemic control that was not found in the majority of our patients. Diabetes care teams should rethink the approaches to patients and change them to more proactive schedules, reinforcing education, patients’ skills, and empowerment to have positive attitudes toward reaching and maintaining a better glycemic control. Finally, the glucocentric

  15. Biodiversity in vegetable crops, a heritage to save: the case of Puglia region

    Directory of Open Access Journals (Sweden)

    Antonio Elia

    2013-03-01

    for which there is a strong link with the Puglia traditions and which are described in this review are: carota di Polignano (Polignano carrot and carota di sant’Ippazio (Saint Ippazio carrot (Apiaceae, cipolla di Acquaviva delle Fonti (Acquaviva delle Fonti onion and cipolla bianca di Margherita (Margherita white onion (Liliaceae, cima di rapa (broccoli raab (Brassicaceae, unripe melon - carosello, barattiere, meloncella, etc. (Cucurbitaceae, catalogna chicory - cicoria di Molfetta e cicoria di Galatina (Molfetta’s chicory and Galatina’s chicory (Asteraceae.

  16. International Uranium Resources Evaluation Project (IUREP) national favourability studies: Mexico

    International Nuclear Information System (INIS)

    1977-07-01

    Reserves of uranium are located in the north eastern part of Mexico, primarily in the states of Tamaulipas and Chihuahua. Most of the remainder of Mexico's reserves are near the Tamaulipas-Neuvo Leon state border in the Tertiary Frio Formation, where they apparently occur in the types of uranium deposits found in Texas, U.S.A. There are two deposits, La Coma and Buenavista, but nothing has been published on dimensions of the ore bodies. Forty-five miles northeast of Hermosillo, in Sonora state is the Los Amoles district where uranium is found associated with gold and other metals in low-grade deposits on the margins of a Cretaceous batholith. Another occurrence is reported in the mining district of Placer de Guadelupe and Puerto del Aire, about 40-50 km northeast of Chihuahua City, in the state of Chihuahua. Reserves of U 3 O 8 which were published in January 1977 by Nuclear Exchange Corporation of Menlo Park, California, are listed. The government of Mexico has not estimated potential resources. It should be noted that much of Mexico appears favourable for uranium, and only 10 percent has been explored. According to NUEXCO (1977), efforts to find uranium are being increased in an attempt to supply Mexico's nuclear reactor requirements through 1990. Activity is reported to be centered in Tamaulipas and Chihuahua states and to a lesser extent in Nueva Leon, Sonora, Coahuila, and Baja California. Major effort will continue to be placed in Chihuahua state to supply the Penna Bianca mill. Correspondence between favorable geological settings for uranium and the geologic regions of Mexico is reported. Mexico is a country with considerable areas that appear promising for discovery of sandstone, vein, and tuff-related deposits. On the other hand, its potential for Precambrian conglomerate and unconformity-related deposits is limited. Considering these geologic factors, as well as the relatively limited amount of exploration done to date, a guesstimate of speculative

  17. Biological differences between melancholic and nonmelancholic depression subtyped by the CORE measure

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    Spanemberg L

    2014-08-01

    Full Text Available Lucas Spanemberg,1,2 Marco Antonio Caldieraro,1 Edgar Arrua Vares,1 Bianca Wollenhaupt-Aguiar,3,4 Márcia Kauer-Sant’Anna,3,4 Sheila Yuri Kawamoto,1 Emily Galvão,3–5 Gordon Parker,6,7 Marcelo P Fleck1,8 1Mood Disorders Program, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, 2Department of Psychiatry, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, 3INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, 4Bipolar Disorders Program and Laboratory of Molecular Psychiatry, Universidade Federal do Rio Grande do Sul, 5Centro Universitário Metodista, Porto Alegre, Brazil; 6School of Psychiatry, University of New South Wales, 7Black Dog Institute, Sydney, NSW, Australia; 8Neuromodulation Research Clinic, Douglas Mental Health University Institute, Montréal, ON, Canada Background: The purpose of this study was to compare melancholic patients rated by the CORE measure of observable psychomotor disturbance with nonmelancholic and control subjects across a set of biomarkers.Methods: Depressed patients were classified as melancholic or nonmelancholic by using the CORE measure. Both groups of patients, as well as control subjects, were compared for a set of clinical and laboratory measures. Serum levels of brain-derived neurotrophic factor, of two markers of oxidative stress (protein carbonyl content [PCC] and thiobarbituric acid reactive substances [TBARS], and of several immunity markers (interleukin [IL]-2, IL-4, IL-6, IL-10, IL-17, tumor necrosis factor-alpha, and interferon-gamma were analyzed. Results: Thirty-three depressed patients and 54 healthy controls were studied. Depressive patients showed higher IL-4, IL-6, and PCC values than healthy controls. Thirteen (39% of the depressed patients were assigned as melancholic by the CORE measure. They generated lower interferon-gamma (compared with nonmelancholic depressed patients and TBARS (compared with both the

  18. How an Anglo-American methodology took root in France.

    Science.gov (United States)

    Laszlo, Pierre

    2011-01-01

    French organic chemistry had a strong nationalistic bent in the immediate aftermath to World War II. It continued to bask in the glow of the pre-World War I Nobel prize awarded jointly in 1912 to Victor Grignard and Paul Sabatier. In addition, the influence of the two mandarins then in power, Charles Prévost at the Sorbonne and Albert Kirrmann, a Dean in Strasbourg who would be called upon as vice-director at the École normale supérieure in Paris, saw to it that the only theory of organic reactions, admissible in the classroom and in the laboratory, was Prévost's. As Mary Jo Nye has shown, a wall was erected against penetration of the ideas of the British school of Ingold and Hughes. Mechanistic chemistry, as was being vigorously studied by the contemporary Anglo-American physical organic chemists, was 'persona non grata' in France. Publication by Bianca Tchoubar, in 1960, of "Les mécanismes réactionnels en chimie organique" opened a breach. The irony was for Dr. Tchoubar, a militant member of the Communist Party and a lady of fierce opinions, to have become a propagandist for the Anglo-American school of mechanistic studies. Truth for her overruled political propaganda. Her little book was revolutionary in the French context of the times. Together with the GECO (Groupe d'étude de chimie organique) summer conferences pioneered by Guy Ourisson after his return from Harvard, it ushered in the new ideas. This historical essay, based on an in-depth study of Tchoubar's book, will include a portrait of this remarkable woman scientist. It will delve at some length into the renewal of French science initiated by De Gaulle's government after his return to power in 1958. The tension in the French scientific establishment of the sixties reflected two opposed versions of nationalism, the one conservative, Malthusian, inner-directed, the other forward-looking, eager for the recovery of national status, seeing a strong French science as a means for asserting national

  19. Risks versus benefits of medication use during pregnancy: what do women perceive?

    Directory of Open Access Journals (Sweden)

    Mulder B

    2017-12-01

    Full Text Available Bianca Mulder,1 Maarten J Bijlsma,1 Catharina CM Schuiling-Veninga,1 Leonard P Morssink,2 Eugene van Puijenbroek,3,4 Jan G Aarnoudse,5 Eelko Hak,1 Tjalling W de Vries6 1Groningen Research Institute of Pharmacy, Unit PharmacoTherapy, Epidemiology & Economics, University of Groningen, Groningen, the Netherlands; 2Department of Obstetrics and Gynaecology, Medical Center Leeuwarden, Leeuwarden, the Netherlands; 3Netherlands Pharmacovigilance Centre Lareb, ´s-Hertogenbosch, the Netherlands; 4Unit of Pharmacotherapy and Pharmaceutical Care, Department of Pharmacy, University of Groningen, Groningen, the Netherlands; 5Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; 6Department of Pediatrics, Medical Center Leeuwarden, Leeuwarden, the Netherlands Background: Understanding perception of risks and benefits is essential for informed patient choices regarding medical care. The primary aim of this study was to evaluate the perception of risks and benefits of 9 drug classes during pregnancy and associations with women’s characteristics.Methods: Questionnaires were distributed to pregnant women who attended a Dutch Obstetric Care facility (first- and second-line care. Mean perceived risk and benefit scores were computed for 9 different drug classes (paracetamol, antacids, antibiotics, antifungal medication, drugs against nausea and vomiting, histamine-2 receptor antagonists/proton pump inhibitors, antidepressants, nonsteroidal anti-inflammatory drugs, and sedatives/anxiolytics. For each participant, we computed weighted risk and benefit sum scores with principal component analysis. In addition, major concerns regarding medication use were evaluated.Results: The questionnaire was completed by 136 women (response rate 77%. Pregnant women were most concerned about having a child with a birth defect (35%, a miscarriage (35%, or their child developing an allergic disease (23

  20. The clinical psychologist and the management of inpatient pain: a small case series

    Directory of Open Access Journals (Sweden)

    Childs SR

    2014-12-01

    Full Text Available Susan R Childs,1,* Emma M Casely,2,* Bianca M Kuehler,1 Stephen Ward,1 Charlotte L Halmshaw,1 Sarah E Thomas,1 Ian D Goodall,1 Carsten Bantel1,3 1Pain Medicine, Chelsea and Westminster Hospital NHS Foundation Trust, London, 2Anaesthetic Department, Hillingdon Hospital, Uxbridge, 3Section of Anaesthetics, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital Campus, London, UK *These authors contributed equally to this manuscript Abstract: Recent research has confirmed that between 25% and 33% of all hospitalized patients experience unacceptable levels of pain. Studies further indicate that this reduces patient satisfaction levels, lengthens hospital stays, and increases cost. Hospitals are aiming to discharge patients earlier, and this can interfere with adequate pain management. Therefore, the pain service at Chelsea and Westminster Hospital has adapted to this changing model of care. An increasing body of evidence demonstrates that psychological factors are key components of patients’ pain experiences in both acute and chronic pain. Therefore, it is reasonable to suggest a clinical psychologist should be involved in inpatient pain management. This small study discusses three cases that highlight how patient care could be improved by including a clinical psychologist as part of the inpatient pain team. Two cases particularly highlight the active role of the psychologist in the diagnosis and management of common conditions such as fear and anxiety, along with other psychiatric comorbidities. The management therefore employed an eclectic approach adapted from chronic pain and comprising of behavioral, cognitive behavioral, and dialectical behavioral therapeutic techniques blended with brief counseling. The third case exemplifies the importance of nurse-patient interactions and the quality of nurse-patient relationships on patient outcomes. Here, the psychologist helped to optimize

  1. Continuous ambulatory peritoneal dialysis: perspectives on patient selection in low- to middle-income countries

    Directory of Open Access Journals (Sweden)

    Wearne N

    2017-01-01

    Full Text Available Nicola Wearne,1 Kajiru Kilonzo,2 Emmanuel Effa,3 Bianca Davidson,1 Peter Nourse,4 Udeme Ekrikpo,1,5 Ikechi G Okpechi1 1Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa; 2Department of Medicine, Kilimanjaro Christian Medical College, Moshi, Tanzania; 3Department of Medicine, University of Calabar, Calabar, Nigeria; 4Division of Paediatric Nephrology, Red Cross War Memorial Children’s Hospital, Cape Town, South Africa; 5Department of Internal Medicine, University of Uyo, Uyo, Nigeria Abstract: Chronic kidney disease is a major public health problem that continues to show an unrelenting global increase in prevalence. The prevalence of chronic kidney disease has been predicted to grow the fastest in low- to middle-income countries (LMICs. There is evidence that people living in LMICs have the highest need for renal replacement therapy (RRT despite the lowest access to various modalities of treatment. As continuous ambulatory peritoneal dialysis (CAPD does not require advanced technologies, much infrastructure, or need for dialysis staff support, it should be an ideal form of RRT in LMICs, particularly for those living in remote areas. However, CAPD is scarcely available in many LMICs, and even where available, there are several hurdles to be confronted regarding patient selection for this modality. High cost of CAPD due to unavailability of fluids, low patient education and motivation, low remuneration for nephrologists, lack of expertise/experience for catheter insertion and management of complications, presence of associated comorbid diseases, and various socio-demographic factors contribute significantly toward reduced patient selection for CAPD. Cost of CAPD fluids seems to be a major constraint given that many countries do not have the capacity to manufacture fluids but instead rely heavily on fluids imported from developed countries. There is need to invest in fluid manufacturing (either nationally or

  2. The future of naval ocean science research

    Science.gov (United States)

    Orcutt, John A.; Brink, Kenneth

    The Ocean Studies Board (OSB) of the National Research Council reviewed the changing role of basic ocean science research in the Navy at a recent board meeting. The OSB was joined by Gerald Cann, assistant secretary of the Navy for research, development, and acquisition; Geoffrey Chesbrough, oceanographer of the Navy; Arthur Bisson, deputy assistant secretary of the Navy for antisubmarine warfare; Robert Winokur, technical director of the Office of the Oceanographer of the Navy; Bruce Robinson, director of the new science directorate at the Office of Naval Research (ONR); and Paul Gaffney, commanding officer of the Naval Research Laboratory (NRL). The past 2-3 years have brought great changes to the Navy's mission with the dissolution of the former Soviet Union and challenges presented by conflicts in newly independent states and developing nations. The new mission was recently enunciated in a white paper, “From the Sea: A New Direction for the Naval Service,” which is signed by the secretary of the Navy, the chief of naval operations, and the commandant of the Marine Corps. It departs from previous plans by proposing a heavier emphasis on amphibious operations and makes few statements about the traditional Navy mission of sea-lane control.

  3. The starlight night the sky in the writings of Shakespeare, Tennyson, and Hopkins

    CERN Document Server

    Levy, David H

    2016-01-01

    In this updated second edition renowned amateur comet-searcher David H. Levy expands on his work about the intricate relationship between the night sky and the works of English Literature. This revised and expanded text includes new sections on Alfred Lord Tennyson and Gerald Manley Hopkins (both amateur astronomers), extending the time period analyzed in the first edition from early modern literature to encompass the Victorian age. Although the sky enters into much of literature through the ages, British authors offer an especially fertile connection to the heavens, and Levy links the works of seminal authors from Shakespeare on to specific celestial events and scientific advances.  From the impact of comets and supernovae to eclipses, Levy’s ultimate goal in this book is to inspire his readers to do the same thing as their ancestors did so long ago—look up and appreciate the stars. His insights in this revised book spread farther and wider than ever before in this learned and enchanting tour of the ski...

  4. Prescription opioid abuse: pharmacists’ perspective and response

    Directory of Open Access Journals (Sweden)

    Cochran G

    2016-08-01

    Full Text Available Gerald Cochran,1,2 Valerie Hruschak,2 Brooke DeFosse,3 Kenneth C Hohmeier3 1Department of Psychiatry, School of Medicine, 2School of Social Work, University of Pittsburgh, Pittsburgh, PA, 3Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee, Memphis, TN, USA Abstract: Opioid medication abuse and overdose are major concerns for public health, and a number of responses to address these issues have taken place across the US. Pharmacists and the pharmacy profession have made important contributions as a part of the response to this national crisis. This article provides a brief review of the antecedents, driving forces, and health status of patients involved in the opioid medication and overdose epidemic. This review further discusses pharmacy-based actions that have been undertaken to address this issue, including prescription drug monitoring, take-back, and naloxone training/distribution programs. This review likewise examines current efforts underway in the field to educate practitioners and needed future steps that must be taken by pharmacists in order to continue the profession’s pivotal role in working toward resolving this national public health problem. In particular, evidence and arguments are presented for proactively identifying and intervening with patients who abuse and/or are at risk for overdose. Continued and active engagement by pharmacists in these efforts has the potential to result in important reductions in opioid medication abuse and overdose and improvements for patient’s health. Keywords: opioid pain medication, addiction, pharmacy practice

  5. Breast cancer and amyloid bodies: is there a role for amyloidosis in cancer-cell dormancy?

    Directory of Open Access Journals (Sweden)

    Mizejewski GJ

    2017-04-01

    Full Text Available Gerald J Mizejewski Wadsworth Center, New York State Department of Health, Albany, NY, USA Abstract: Breast cancer and Alzheimer’s disease (AD are major causes of death in older women. Interestingly, breast cancer occurs less frequently in AD patients than in the general population. Amyloidosis, the aggregation of amyloid proteins to form amyloid bodies, plays a central role in the pathogenesis of AD and other human neuropathies by forming intracellular fibrillary proteins. Contrary to popular belief, amyloidosis is a common occurrence in mammalian cells, and has recently been reported to be a natural physiological process in response to environmental stress stimulations (such as pH and temperature extremes, hypoxia, and oxidative stress. Many proteins contain an intrinsic “amyloid-converting motif”, which acts in conjunction with a specific noncoding RNA to induce formation of proteinaceous amyloid bodies that are stored in intracellular bundles. In cancer cells such as breast and prostate, the process of amyloidosis induces cells to enter a dormant or resting stage devoid of cell division and proliferation. Therefore, cancer cells undergo growth cessation and enter a dormant stage following amyloidosis in the cell; this is akin to giving the cell AD to cease growth. Keywords: α-fetoprotein, noncoding RNA, amyloid bodies, dormancy, breast cancer, Alzheimer’s disease

  6. Howard Brenner's Legacy for Biological Transport Processes

    Science.gov (United States)

    Nitsche, Johannes

    2014-11-01

    This talk discusses the manner in which Howard Brenner's theoretical contributions have had, and long will have, strong and direct impact on the understanding of transport processes occurring in biological systems. His early work on low Reynolds number resistance/mobility coefficients of arbitrarily shaped particles, and particles near walls and in pores, is an essential component of models of hindered diffusion through many types of membranes and tissues, and convective transport in microfluidic diagnostic systems. His seminal contributions to macrotransport (coarse-graining, homogenization) theory presaged the growing discipline of multiscale modeling. For biological systems they represent the key to infusing diffusion models of a wide variety of tissues with a sound basis in their microscopic structure and properties, often over a hierarchy of scales. Both scientific currents are illustrated within the concrete context of diffusion models of drug/chemical diffusion through the skin. This area of theory, which is key to transdermal drug development and risk assessment of chemical exposure, has benefitted very directly from Brenner's contributions. In this as in other areas, Brenner's physicochemical insight, mathematical virtuosity, drive for fully justified analysis free of ad hoc assumptions, quest for generality, and impeccable exposition, have consistently elevated the level of theoretical understanding and presentation. We close with anecdotes showing how his personal qualities and warmth helped to impart high standards of rigor to generations of grateful research students. Authors are Johannes M. Nitsche, Ludwig C. Nitsche and Gerald B. Kasting.

  7. International trade and waste and fuel management issue, 2009

    Energy Technology Data Exchange (ETDEWEB)

    Agnihotri, Newal (ed.)

    2009-01-15

    The focus of the January-February issue is on international trade and waste and fuel managment. Major articles/reports in this issue include: Innovative financing and workforce planning, by Donna Jacobs, Entergy Nuclear; Nuclear power - a long-term need, by John C. Devine, Gerald Goldsmith and Michael DeLallo, WorleyParsons; Importance of loan guarantee program, by Donald Hintz; EPC contracts for new plants, by Dave Barry, Shaw Power Group; GNEP and fuel recycling, by Alan Hanson, AREVA NC Inc.; Safe and reliable reactor, by Kiyoshi Yamauchi, Mitsubishi Heavy Industries, Ltd.; Safe, small and simple reactors, by Yoshi Sakashita, Toshiba Corporation; Nuclear power in Thailand, by Tatchai Sumitra, Thailand Institute of Nuclear Technology; and, Nuclear power in Vietnam, by Tran Huu Phat, Vietnam Atomic Energy Commission. The Industry Innovation article this issue is Rectifying axial-offset-anomaly problems, by Don Adams, Tennessee Valley Authority. The Plant Profile article is Star of Stars Excellence, by Tyler Lamberts, Entergy Nuclear Operations, Inc.

  8. PREFACE: Second Meeting of the APS Topical Group on Hadronic Physics

    Science.gov (United States)

    Ernst, David; de Jager, Kees; Roberts, Craig; Sheldon, Paul; Swanson, Eric

    2007-06-01

    The Second Meeting of the APS Topical Group on Hadronic Physics was held on 22-24 October 2006 at the Opryland Resort in Nashville, Tennessee. Keeping with tradition, the meeting was held in conjunction with the Fall meeting of the APS Division of Nuclear Physics. Approximately 90 physicists participated in the meeting, presenting 25 talks in seven plenary sessions and 48 talks in 11 parallel sessions. These sessions covered a wide range of topics related to strongly interacting matter. Among these were charm spectroscopy, gluonic exotics, nucleon resonance physics, RHIC physics, electroweak and spin physics, lattice QCD initiatives, and new facilities. Brad Tippens and Brad Keister provided perspective from the funding agencies. The organisers are extremely grateful to the following institutions for financial and logistical support: the American Physical Society, Jefferson Lab, Brookhaven National Laboratory, and Vanderbilt University. We thank the following persons for assisting in organising the parallel sessions: Ted Barnes, Jian-Ping Chen, Ed Kinney, Krishna Kumar, Harry Lee, Mike Leitch, Kam Seth, and Dennis Weygand. We also thank Gerald Ragghianti for designing the conference poster, Will Johns for managing the audio-visual equipment and for placing the talks on the web, Sandy Childress for administrative expertise, and Vanderbilt graduate students Eduardo Luiggi and Jesus Escamillad for their assistance. David Ernst, Kees de Jager, Craig Roberts (Chair), Paul Sheldon and Eric Swanson Editors

  9. A metaficção no romance Budapeste e na sua adaptação fílmica

    Directory of Open Access Journals (Sweden)

    Janio Davila de Oliveira

    2017-07-01

    Full Text Available O objetivo deste trabalho é fazer uma análise comparativa entre o romance Budapeste (2003, de Chico Buarque de Hollanda e sua adaptação fílmica (2009, dirigida por Walter Carvalho. O presente estudo propõe uma análise com enfoque no caráter metaficional das narrativas, elemento que na nossa visão é de grande importância na interpretação das estruturas das duas obras. Para a realização da análise, parte-se da proposta de Robert Stam (2006 de entender a adaptação fílmica como hipertexto. Logo, com base nessa categoria transtextual criada por Gerald Genette (2010, a adaptação fílmica deixa de ser associada à mera cópia e passa a gozar do status de obra original. Deste modo, buscaremos nas duas obras, Budapeste romance e Budapeste filme, entender a importância da metaficção e como ela foi tratada por Walter Carvalho ao ser transposta para a tela

  10. Peer review of RELAP5/MOD3 documentation

    International Nuclear Information System (INIS)

    Craddick, W.G.

    1994-01-01

    A peer review was performed on a portion of the documentation of the RELAP5/MOD3 computer code. The review was performed in two phases. The first phase was a review of Vol. III, Developmental Assessment Problems, and Vol. IV, Models and Correlations. The reviewers for this phase were Dr. Peter Griffith, Dr. Yassin Hassan, Dr. Gerald S. Lellouche, Dr. Marino di Marzo and Mr. Mark Wendel. The reviewers recommended a number of improvements, including using a frozen version of the code for assessment guided by a validation plan, better discussion of discrepancies between the code and experimental data, and better justification for flow regime maps and extension of models beyond their data base. The second phase was a review of Vol. VI, Quality Assurance of Numerical Techniques in RELAP5/MOD3. The reviewers for the second phase were Mr. Mark Wendel and Dr. Paul T. Williams. Recommendations included correction of numerous grammatical and typographical errors and better justification for the use of Lax's Equivalence Theorem

  11. November 2015 Arizona thoracic society notes

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2015-11-01

    Full Text Available No abstract available. Article truncated after 150 words. The November 2015 Arizona Thoracic Society meeting was held on Wednesday, November 18, 2015 at the Scottsdale Shea Hospital beginning at 6:30 PM. This was a dinner meeting with case presentations. There were 14 in attendance representing the pulmonary, critical care, sleep, and radiology communities. There were 3 case presentations: 1. Dr. Gerald Schwartzberg presented a case of a 56-year-old man with a history of diabetes, alcoholism and tobacco abuse who has a history of Mycobacterium avium-intracellulare (MAI with a residual thin-walled cavity in his right upper lobe (RUL. After quitting drinking and smoking and years of being asymptomatic, he presented with hemoptysis. Chest x-ray showed increasing density in the RUL. CT scan showed an intracavitary density in his previous cavity presumably a fungus ball. Sputum cultures are pending. Discussion followed on management of fungus balls. Bronchoscopy was recommended to view the bronchial anatomy to exclude other diagnosis as well ...

  12. Higher cytotoxicity of divalent antibody-toxins than monovalent antibody-toxins

    International Nuclear Information System (INIS)

    Won, JaeSeon; Nam, PilWon; Lee, YongChan; Choe, MuHyeon

    2009-01-01

    Recombinant antibody-toxins are constructed via the fusion of a 'carcinoma-specific' antibody fragment to a toxin. Due to the high affinity and high selectivity of the antibody fragments, antibody-toxins can bind to surface antigens on cancer cells and kill them without harming normal cells [L.H. Pai, J.K. Batra, D.J. FitzGerald, M.C. Willingham, I. Pastan, Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin, Proc. Natl. Acad. Sci. USA 88 (1991) 3358-3362]. In this study, we constructed the antibody-toxin, Fab-SWn-PE38, with SWn (n = 3, 6, 9) sequences containing n-time repeated (G 4 S) between the Fab fragment and PE38 (38 kDa truncated form of Pseudomonas exotoxin A). The SWn sequence also harbored one cysteine residue that could form a disulfide bridge between two Fab-SWn-PE38 monomers. We assessed the cytotoxicity of the monovalent (Fab-SWn-PE38), and divalent ([Fab-SWn-PE38] 2 ) antibody-toxins. The cytotoxicity of the dimer against the CRL1739 cell line was approximately 18.8-fold higher than that of the monomer on the ng/ml scale, which was approximately 37.6-fold higher on the pM scale. These results strongly indicate that divalency provides higher cytotoxicity for an antibody-toxin.

  13. The mystery of consciousness

    CERN Document Server

    Searle, John R

    1997-01-01

    It has long been one of the most fundamental problems of philosophy, and it is now, John Searle writes, "the most important problem in the biological sciences": What is consciousness? Is my inner awareness of myself something separate from my body? In what began as a series of essays in The New York Review of Books, John Searle evaluates the positions on consciousness of such well-known scientists and philosophers as Francis Crick, Gerald Edelman, Roger Penrose, Daniel Dennett, David Chalmers, and Israel Rosenfield. He challenges claims that the mind works like a computer, and that brain functions can be reproduced by computer programs. With a sharp eye for confusion and contradiction, he points out which avenues of current research are most likely to come up with a biological examination of how conscious states are caused by the brain. Only when we understand how the brain works will we solve the mystery of consciousness, and only then will we begin to understand issues ranging from artificial intelligence...

  14. Problèmes linguistiques dans le système multilingues Linguistic Problems in Multilingual Systems

    Directory of Open Access Journals (Sweden)

    Moureau M.

    2006-11-01

    Full Text Available La communauté scientifique est internationale. L'industrie du pétrole est internationale. Des problèmes de communication, de langage, de langue y sont rencontrés chaque jour. C'est pourquoi, bien que tranchant assez vigoureusement sur les sujets habituels de la Revue de l'Institut Français du Pétrole, l'article de Magdeleine Moureau et Gerald Brace sur des problèmes de linguistique ne nous a pas paru trop étranger aux préoccupations de nos lecteurs pour leur être présenté. Cet article a pour but de traiter d'abord des impossibilités théoriques de la traduction, d'évoquer ensuite les modalités pratiques de sa réalisation quotidienne et de les appliquer à l'étude des problèmes inhérents à l'élaboration d'un langage documentaire multilinguisme. The aim of this paper is to discuss the theoretical impossibilities of translation, and then to describe the practical ways of actually translating, and to apply these ways to the task of studying problems inherent in elaborating a multilingual documentary language.

  15. Juridical-Criminal Paternalism, Autonomy and Vulnerability: Legitimation Criteria of Paternalistic Interventions on Individual Autonomy in Criminal Matters

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    Heráclito Mota Barreto Neto

    2015-12-01

    Full Text Available The following paper has as objective questioning the legitimacy of state's paternalistic interventions on individual autonomy by using institutional-criminal instruments. In this path, the paper aims to understand in which cases the State is allowed to interfere in private individual lives under the justification of being promoting a well or avoiding a harm and, as well, in which cases such interference is abusive of individuals self-determination. Into this analysis, the work will study the current concepts of paternalism, the theoretical classifications on paternalistic interventions which will be useful to demonstrate admissible and inadmissible species of paternalism and Joel Feinberg and Gerald Dworkin's anti- paternalistic theories. Following, this subject will be analyzed in association with the implications of juridical-criminal goods involved in conflicts between autonomy, human vulnerabilities and paternalism, specially regarding to the (unavailability of those goods. In the end, the work intends to define legitimation criteria for paternalistic interventions inserted in criminal laws, which superimpose themselves on the individual autonomy, in order to harmonize constitutional values of respect for autonomy, protection of vulnerable individuals and the Criminal Law functions of exclusive protection of juridical goods.

  16. Dynamically remembered present: Virtual memory as a basis for the stories we live

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    Cornelius W. du Toit

    2013-06-01

    Full Text Available In this article memory was viewed as a crucial key to the discovery of reality. It is the basis of historical research at all levels, hence it is not confined to a function of human consciousness (brain operations: its physical vestiges are discernible in the universe, in fossils, in the DNA of species. Memory inscribes information in various ways. On a human level it is not recalled computer-wise: imagination, emotion and tacit motives play a role in how we remember. The article investigated the way in which memory underlies the operation of every cell in any living organism. Against this background the role of memory in humans and its decisive influence on every level of human life are examined. Gerald Edelman’s work in this regard was considered. Marcel Proust’s focus on memory is an underlying thread running through his novels, unrivalled in literary history. Some prominent examples were analysed in this article. In light of the foregoing the role of memory in religious experience was then discussed. The virtuality of memory is encapsulated in the statement that we remember the present whilst reliving the past. Memory characterised by virtuality is basic to our autobiographic narratives. The nature of memory determines our life stories, hence our perception of the human self as dynamically variable and open to the future.

  17. 'The televising of science is a process of television': establishing Horizon, 1962-1967.

    Science.gov (United States)

    Boon, Timothy

    2015-03-01

    BBC Television's Horizon series, fifty years old on 2 May 2014, despite its significance to the history of the public culture of science, has been little studied. This microhistorical account follows the gestation and early years of the programme, demonstrating how it established a social and cultural account of science. This was a result of televisual factors, notably the determination to follow the format of the successful arts television programme Monitor. It illuminates how the processes of television production, with a handful of key participants - Aubrey Singer, Gerald Leach, Philip Daly, Gordon Rattray Taylor, Ramsay Short, Michael Peacock and Robert Reid - established the format of the programme. This occurred over seventeen months of prior preparation followed by three troubled years of seeking to establish a stable form. This was finally achieved in 1967 when the programme adopted a film documentary approach after extended attempts at making it as a studio-based magazine programme. The story has implications for understanding the social accounts of science that were circulating in the key decade of the 1960s.

  18. Relativistic length agony continued

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    Redžić D.V.

    2014-01-01

    Full Text Available We made an attempt to remedy recent confusing treatments of some basic relativistic concepts and results. Following the argument presented in an earlier paper (Redžić 2008b, we discussed the misconceptions that are recurrent points in the literature devoted to teaching relativity such as: there is no change in the object in Special Relativity, illusory character of relativistic length contraction, stresses and strains induced by Lorentz contraction, and related issues. We gave several examples of the traps of everyday language that lurk in Special Relativity. To remove a possible conceptual and terminological muddle, we made a distinction between the relativistic length reduction and relativistic FitzGerald-Lorentz contraction, corresponding to a passive and an active aspect of length contraction, respectively; we pointed out that both aspects have fundamental dynamical contents. As an illustration of our considerations, we discussed briefly the Dewan-Beran-Bell spaceship paradox and the ‘pole in a barn’ paradox. [Projekat Ministarstva nauke Republike Srbije, br. 171028

  19. Why threefold-replication of families?

    Science.gov (United States)

    Fitzpatrick, Gerald L.

    1998-04-01

    In spite of the many successes of the standard model of particle physics, the observed proliferation of matter-fields, in the form of ``replicated'' generations or families, is a major unsolved problem. In this paper, I explore some of the algebraic, geometric and physical consequences of a new organizing principle for fundamental fermions (quarks and leptons)(Gerald L. Fitzpatrick, phThe Family Problem--New Internal Algebraic and Geometric Regularities), Nova Scientific Press, Issaquah, Washington, 1997. Read more about this book (ISBN 0--9655695--0--0) and its subject matter at: http://www.tp.umu.se/TIPTOP and/or amazon.com>http://www.amazon.com.. The essence of the new organizing principle is the idea that the standard-model concept of scalar fermion numbers f can be generalized. In particular, a ``generalized fermion number,'' which consists of a 2× 2 matrix F that ``acts'' on an internal 2-space, instead of spacetime, is taken to describe certain internal properties of fundamental fermions. This generalization automatically introduces internal degrees of freedom that ``explain,'' among other things, family replication and the number (three) of families observed in nature.

  20. González de la Vega, René. (2017. Tolerance and Modern Liberalism. From Paradox to Aretaic Moral Ideal. Maryland, United States of America: Lexington. 231 pp.

    Directory of Open Access Journals (Sweden)

    Guillermo Lariguet

    2017-06-01

    Full Text Available In political and moral philosophy we are used to an uninterrupted succession of texts, heirs of the liberal traditions (headed by John Rawls, communitarians (led by the likes of Michael Sandel, Charles Taylor, etc., analytical Marxists (authors like Gerald Cohen, Jon Elster, etc..Besides the names mentioned above, there is a succession of texts that tend to give rise to a sense of routine and, as a result, of lethargy. It is the feeling that political and moral philosophy has reached a plateau within a set of accepted doctrines. Doctrines which, to paraphrase Thomas Kuhn, make up a kind of “normal science” of philosophical theory.But from time to time, the routine drowsiness is sharply interrupted. This happens when works of philosophy show up to question prevailing theories in political philosophy. Such is the case of the work I propose to review herein. It is the work of Mexican philosopher René González de la Vega, whose text on political philosophy features philosophical rigour, originality and depth...

  1. Desmoplastic round small cell tumor: a case report of a neoplasm of difficult diagnosis

    International Nuclear Information System (INIS)

    Ogata, Daniel Cury; Totsugui, Joel Takashi; Ditzel Filho, Leo Fernando da Silva; Ioshii, Sergio Ossamu; Machuca, Tiago Noguchi; Ogata, Alessandro Cury

    2005-01-01

    Desmoplastic Small Round Cell Tumor (DSRCT) is a rare neoplasm of difficult diagnosis, recently described by Gerald et al. There are reports of nearly 101 cases in the literature, being the intra-abdominal region its most common location and children and young adults its preferred age group. This paper reports a case of DSRCT in a young adult of 24 years of age. This patient presented unspecific symptoms of nausea, vomiting and a single episode of haematemesis. Upon physical examination a solid mass on the epigastrium and left hypochondrium was found. Image diagnostic procedures confirmed the existence of the expansive process and also revealed enlarged retroperitoneal lymphonodes. Diagnosis was achieved through videolaparoscopic biopsy. Histologic sections stained with hematoxylin/eosin were inconclusive and immunohistochemical analysis was required to establish the diagnosis. This analysis revealed positivity to epithelial and mesenchymal markers and weak positivity to chromogranin A, characteristic results of DSRCT. Due to the fact that the disease was locally advanced, the patient was treated with chemotherapy (cyclophosphamide and paclytaxel). However, since there was only partial response to the treatment, the patient refused to undergo any second line option of therapy. Presently, the patient is being submitted only to supportive care, within an 18-month follow-up program. (author)

  2. [The neurodynamic core of consciousness and neural Darwinism].

    Science.gov (United States)

    Ibáñez, A

    In the last decades, the scientific study of consciousness in the scope of the cognitive neurosciences can be considered one of the greatest challenges of contemporary science. The Gerald Edelman theory of consciousness is one of the most promising and controversial perspectives. This theory stands out by its approach to topics usually rejected by other neurophysiologic theories of consciousness, as the case of the neurophysiologic explanation of qualia. The goal of this paper is to review the dynamic core theory of consciousness, presenting the main features of the theory, analyzing the explanation strategies, their empirical extensions, and elaborating some critical considerations about the possibility of the neuroscientific study of qualia. The central and additional theoretical components are analyzed, emphasizing its ontological, restrictive and explanatory assumptions. The properties of conscious phenomena and their cerebral correlates as advanced by the theory are described, and finally its experiments and empirical extensions are examined. The explanatory strategies of the theory are analyzed, based on conceptual isomorphism between the phenomenological properties and the neurophysiological and mathematical measures. Some criticisms could be raised about the limitations of the dynamic core theory, especially regarding its account of the so-called 'hard problem' of consciousness or qualia.

  3. Self-Ownership and Freedom: Reasons for Maintaining a Traditional Connection

    Directory of Open Access Journals (Sweden)

    Tutui Viorel

    2016-07-01

    Full Text Available Abstract: In this paper I present and analyze the classical libertarian thesis according to which there is an intimate connection between humans‟ right to self-ownership and their freedom, and I provide some reasons for preserving this traditional connection against its egalitarian contesters, represented by Gerald Allan Cohen. The principle states that humans have a right of property over their persons and powers, and any interference with this right is equivalent to a violation of their freedom. This is the reason why an egalitarian thinker like Cohen tries to reject the principle and its connection with freedom in order to legitimate redistribution of property in the benefit of the underprivileged: he argues that the principle itself (and particularly Robert Nozick‟s version of it has no special relation with freedom and lacks any real significance for political philosophy. I will reject his argumentation and evidentiate that the traditional connection still stands and the principle is indeed useful. In the last section I will formulate what I believe to be a more robust justification of it and offer some suggestions about the central role it could play in a general explanation of social and political legitimacy and normativity.

  4. Werner Heisenberg - Life and Work

    CERN Multimedia

    2002-01-01

    Werner Heisenberg (centre) with Wolfgang Pauli (left) and Enrico Fermi on Lake Como, September 1927. An exhibition on the life and work of Werner Heisenberg will be on display in the Main Building (Mezzanine) at CERN from 1 - 23 July. The exhibition was produced by the University Archive of Leipzig University (Gerald Wiemers) and the Max-Planck-Institut für Physik in Munich (Helmut Rechenberg) to mark the centenary of Heisenberg's birth in 1901. German theoretical physicist Werner Karl Heisenberg (5 December 1901 - 1 February 1976) was one of the leading scientists of the 20th century. He carried out important work in nuclear and particle physics, but his most significant contribution was to the development of quantum mechanics. He is best known for his uncertainty principle, which restricts the accuracy with which some properties of atoms and particles - such as position and linear momentum - can be determined simultaneously. In 1932 he was awarded the Noble Prize in Physics 'for the creation of q...

  5. Even an old technique is suitable in the molecular world of science: the everted sac preparation turns 60 years old.

    Science.gov (United States)

    Hamilton, Kirk L

    2014-04-15

    An old proverb states "necessity is the mother of invention." This certainly holds true in science as one pursues research questions. Experimental techniques have evolved as scientists have asked more specific research questions. Indeed, techniques such as the Ussing chamber, the perfused renal tubule preparation, patch-clamp, polymerase chain reaction, and site-directed mutagenesis have been developed over the past 60 years. However, sometimes, simple techniques may be useful and still very informative, and this certainly applies to intestinal physiology. Indeed, Gerald Wiseman and Thomas Hastings Wilson described the intestinal everted sac preparation some 60 years ago. Since then, this technique has been used for numerous research purposes including determining ion, amino acid, water and solute transport across the intestinal epithelium; and drug metabolism, absorption, and interactions in pharmaceutical/pharmacological research and even in education. This article provides a historical review of the development of the in vitro intestinal preparation that led to the everted sac preparation and its use in science.

  6. Romanian Association of Balneology Conference – 2015, 28 – 31 May, Băile Tuşnad

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    MUNTEANU Constantin

    2015-05-01

    Full Text Available 1.\tProf. Onose G, MD, PhD, MSc, Univ. Assist. Haras MA, MD, PhD, Prof. Sinescu CJ, MD, PhD1,2, Univ. Assist. Daia CO, MD, PhD1,2, RDI Assist. Andone I, MD, Postgrad2, Onose VL, MD,3, Assist. Prof. Capisizu A, MD, PhD1,4, Prof. Grigorean VT, MD, PhD1,2, Assoc. Prof. Ciobotaru C, MD, PhD5,6, Sandu AM, MD, Postgrad.2, Assist. Prof. Blendea CD, MD, PhD7, 8 - BASIC WELLNESS FEATURES AND SOME RELATED ACTIONS, PROPENSIVE INCLUDING FOR ACTIVE AND HEALTHY AGEING - 2.\tOlga SURDU, T.V. SURDU, Monica SURDU - STATE OF ART of balneotherapy/thermalisme in Romania 3.\tIliuta Maria Alexandra - THE IMPORTANCE OF NUTRITION IN HEALTH PROGRAMS 4.\tDr. Dogaru Gabriela - THERAPEUTIC EFFECTS OF MINERAL WATERS IN RENAL DISEASES 5.\tVeryho N.S. - THERAPEUTIC EFFECT OF MINERAL WATER WITH DIFFERENT CONCENTRATIONS OF HUMIC ACIDS IN EXPERIMENTAL HEPATITIS INDUCED BY ACETAMINOPHEN 6.\tIoana Marian - SPA SEEN AS AN EXTENSION OF A HEALTH RESORT - A NECESSARY CONDITION FOR INTEGRATING ROMANIA IN THE LIST OF GLOBAL WELLNESS TOURISM DESTINATIONS 7.\tBilha Neli-Claudia, Bilha Stefan - THE BALNEARY TREATMENT COURSE – A BREATH OF LIFE 8.\tBilha Neli-Claudia, Bilha Stefan - WICH SALT MINE DO YOU RECOMMEND FOR SPELEOTHERAPY? Interdisciplinary project proposal. 9.\tGáspár Boróka, Gabriela Dogaru - BALNEOTHERAPY IN THE BOGHIŞ RESORT 10.\tDr. Luminita Aurelia Pasca - REHABILITATION OF ELDERLY PATIENTS WITH CARDIOVASCULAR DISEASE 11.\tDr. Luminita Aurelia Pasca, Dr. Valer Donca - GEROVITAL – PROPHYLAXIS OF AGING AND GERIATRIC TREATMENT 12.\tAndronache Cristina - IMPORTANCE OF REHABILITATION TREATMENT IN HEMOPHILIC ARTHROPATHY – A CASE REPORT 13.\tDr. Motricala Marieta, Molnar Akos - BALNEOTHERAPY IN BAILE TUSNAD 14.\tIoana Pop, Bianca Pop - MEDICAL REHABILITATION IN NEUROPATHIC PAIN 15.\tAmalia Salca¹, Nicoleta Stoica1, Gabriela Dogaru¹,² - BALNEOTHERAPY IN GONARTHROSIS 16.\tAlexandru Bogdan-Cătălin, Toşa Edith-Éva - USING PULSED SHORT WAVE (DIAPULSE COMPLEMENTARY TO

  7. Introduction and Committees

    Science.gov (United States)

    Angelova, Maia; Zakrzewski, Wojciech; Hussin, Véronique; Piette, Bernard

    2011-03-01

    This volume contains contributions to the XXVIIIth International Colloquium on Group-Theoretical Methods in Physics, the GROUP 28 conference, which took place in Newcastle upon Tyne from 26-30 July 2010. All plenary and contributed papers have undergone an independent review; as a result of this review and the decisions of the Editorial Board most but not all of the contributions were accepted. The volume is organised as follows: it starts with notes in memory of Marcos Moshinsky, followed by contributions related to the Wigner Medal and Hermann Weyl prize. Then the invited talks at the plenary sessions and the public lecture are published followed by contributions in the parallel and poster sessions in alphabetical order. The Editors:Maia Angelova, Wojciech Zakrzewski, Véronique Hussin and Bernard Piette International Advisory Committee Michael BaakeUniversity of Bielefeld, Germany Gerald DunneUniversity of Connecticut, USA J F (Frank) GomesUNESP, Sao Paolo, Brazil Peter HanggiUniversity of Augsburg, Germany Jeffrey C LagariasUniversity of Michigan, USA Michael MackeyMcGill University, Canada Nicholas MantonCambridge University, UK Alexei MorozovITEP, Moscow, Russia Valery RubakovINR, Moscow, Russia Barry SandersUniversity of Calgary, Canada Allan SolomonOpen University, Milton Keynes, UK Christoph SchweigertUniversity of Hamburg, Germany Standing Committee Twareque AliConcordia University, Canada Luis BoyaSalamanca University, Spain Enrico CeleghiniFirenze University, Italy Vladimir DobrevBulgarian Academy of Sciences, Bulgaria Heinz-Dietrich DoebnerHonorary Member, Clausthal University, Germany Jean-Pierre GazeauChairman, Paris Diderot University, France Mo-Lin GeNankai University. China Gerald GoldinRutgers University, USA Francesco IachelloYale University, USA Joris Van der JeugtGhent University, Belgium Richard KernerPierre et Marie Curie University, France Piotr KielanowskiCINVESTAV, Mexico Alan KosteleckyIndiana University, USA Mariano del Olmo

  8. Das Anreizargument in Wirtschaftsethik und Gerechtigkeitstheorie

    Directory of Open Access Journals (Sweden)

    Neuhäuser Christian

    2016-12-01

    Full Text Available Die Idee, dass vor allem monetäre Anreize das Verhalten von Wirtschaftsakteuren in gewünschte Richtungen lenken und sogar dabei helfen können, durch Leistungssteigerung zusätzliche Wohlfahrtseffekte zu generieren, spielt in der politischen Ökonomie seit ihren Anfängen eine zentrale Rolle. Es spricht sogar einiges dafür, dass dieser Gedanke das verbindende Glied der Ökonomik als Gesellschaftstheorie im Gegensatz zu anderen gesellschaftstheoretischen Entwürfen ausmacht. Dennoch halte ich dieses Anreizargument aus normativer Perspektive für unterentwickelt, wie ich in Auseinandersetzung mit der Ökonomischen Ethik bzw. Ordnungsethik nach Karl Homann und der Integrativen Wirtschaftsethik zeigen möchte. Weder gelingt es der Ordnungsethik nach Karl Homann, die Bedeutung von Anreizstrukturen hinreichend zu begründen, obwohl sie in Ansätzen wichtige Argumente formuliert. Noch gelingt es der Integrativen Wirtschaftsethik, die zentrale Rolle von Anreizstrukturen für die normative Theoriebildung überzeugend zurückzuweisen. Mir geht es nicht darum, den einen oder anderen wirtschaftsethischen Ansatz grundsätzlich zurückzuweisen, sondern vielmehr, auf Lücken in der Argumentation und sich daraus ergebende Forschungsfragen hinzuweisen. Vor diesem Hintergrund könnte es helfen, einen verwandten Diskurs aus der gegenwärtigen Gerechtigkeitstheorie in die Überlegungen mit einzubeziehen. Denn die grundlegende Idee der ökonomischen Gesellschaftstheorie einer Wohlfahrtssteigerung durch die gezielte Manipulation von Anreizstrukturen hat auch in der gegenwärtigen Gerechtigkeitstheorie ihre Wirkung entfaltet. In seiner Theorie der Gerechtigkeit hat John Rawls argumentiert, dass selbst Egalitaristen bestimmte Einkommensunterschiede zulassen müssen, wenn dadurch für Leistungsträgerinnen solche Anreize gesetzt werden, die gleichzeitig auch den Schlechtestgestellten zum Vorteil gereichen. Diese Argumentation ist von Gerald Cohen einer harschen

  9. Visions of Discovery

    Science.gov (United States)

    Chiao, Raymond Y.; Cohen, Marvin L.; Leggett, Anthony J.; Phillips, William D.; Harper, Charles L., Jr.

    2010-10-01

    physics? Steven Chu; 20. Quantum information J. Ignacio Cirac; 21. Emergence in condensed matter physics Marvin L. Cohen; 22. Achieving the highest spectral resolution over the widest spectral bandwidth: precision measurement meets ultrafast science Jun Ye; 23. Wireless non-radiative energy transfer Marin Soljačić; Part V. Consciousness and Free Will: 24. The big picture: exploring questions on the boundaries of science - consciousness and free will George F. R. Ellis; 25. Quantum entanglement: from fundamental questions to quantum communication and quantum computation and back Anton Zeilinger; 26. Consciousness, body, and brain: the matter of the mind Gerald M. Edelman; 27. The relation between quantum mechanics and higher brain functions: lessons from quantum computation and neurobiology Christof Koch and Klaus Hepp; 28. Free will and the causal closure of physics Robert C. Bishop; 29. Natural laws and the closure of physics Nancy L. Cartwright; 30. Anti-Cartesianism and downward causation: reshaping the free-will debate Nancey Murphy; 31. Can we understand free will? Charles H. Townes; Part VI. Reflections on the Big Questions: Mind, Matter. Mathematics, and Ultimate Reality: 32. The big picture: exploring questions on the boundaries of science - mind, matter, mathematics George F. R. Ellis; 33. The mathematical universe Max Tegmark; 34. Where do the laws of physics come from? Paul C. W. Davies; 35. Science, energy, ethics, and civilization Vaclav Smil; 36. Life of science, life of faith William T. Newsome; 37. The science of light and the light of science: an appreciative theological reflection on the life and work of Charles Hard Townes Robert J. Russell; 38. Two quibbles about 'ultimate' Gerald Gabrielse; Index.

  10. Síndrome metabólico vs síndrome de insulinorresistencia. Diferentes términos, clasificaciones y enfoques: ¿existe o no? Metabolic syndrome vs insulin resistance syndrome. Different terms, classifications and approaches: Does it exist or not?

    Directory of Open Access Journals (Sweden)

    Raúl Orlando Calderín Bouza

    2006-12-01

    Full Text Available Aunque Gerald M. Reaven describió en 1988 el síndrome X, múltiples nombres ha recibido este con el decursar del tiempo. Los de mayor aceptación son: síndrome metabólico (SM y síndrome de insulinorresistencia (SIR. El primero se refiere a una constelación de factores de riesgo de lípidos y no lípidos de origen metabólico, mientras que el segundo, el más completo y adecuado, describe un grupo de anormalidades y resultados clínicos relacionados, que ocurren más comúnmente en individuos con insulinorresistencia (IR e hiperinsulinemia compensatoria asociada a un estado inflamatorio crónico. Se ha cuestionado por algunos autores su existencia, pero las evidencias de que existe hablan por sí solas. El objetivo de esta revisión es hacer un análisis de los diferentes enfoques y clasificaciones para su diagnóstico, recomendar la clasificación de la NCEP-ATP III, por su factibilidad, aplicación en la práctica clínica y en los estudios epidemiológicos, e insistir en la visión de que el SIR es la resultante de la IR, así como de un estado inflamatorio crónico asociado a varios factores de riesgo cardiovascular (FRCV y de situaciones clínicas afines que le confieren a este un riesgo elevado de desarrollar diabetes mellitus tipo 2 (DM 2 y enfermedad cardiovascular (ECV.Eventhough Gerald M Reavaen described in 1988 the X syndrome, it has received multiple names in the course of time. The metabolic syndrome (MS and the insulin resistance syndrome (IRS are the most accepted. The first refers to a series of risk factors of lipids and nonlipids of metabolic origin; whereas the second, the most complete and adequate, describes a group of abnormalities and related clinical results that appear more commonly in individuals with insulin resistance (IR and compensatory hyperinsulinemia associated with a chronic inflammatory state. Some authors have questioned its existence, but the evidences speak for themselves. The objective of this review

  11. Gneiss wastes as secondary raw material for the ceramic industry: an example from the Verbano Cusio Ossola district (Piedmont, north-western Alps, Italy)

    Science.gov (United States)

    Cavallo, Alessandro

    2015-04-01

    -feldspathic rocks (i.e. Serizzo and Beola), are potential sources of secondary raw materials for the ceramic industry. To assess the feasibility of a reuse of these waste materials, an extensive sampling was performed on the main quarry dumps. The waste rocks were characterized by polarized light optical microscopy (OM) on thin sections, scanning electron microscopy (SEM), quantitative X-ray powder diffraction (XRD-QPA with the Rietveld method), electron microprobe (WDS and EDS) and whole-rock geochemistry (ICP-AES, ICP-MS and LECO®). The performed analyzes show a marked mineralogical and chemical heterogeneity (e.g. highly variable content of phyllosilicates, FeOtot content between 0.39 and 6.99 wt.%), as well as important textural and granulometric differences. On the other hand, the composition of feldspars is quite homogeneous, with the plagioclase ranging from almost pure albite to oligoclase (An 25 - 30%). Some varieties of Serizzo and Beola (Serizzo Sempione, Serizzo Formazza and Beola Bianca) are preferable because of their relatively low FeOtot content, but granulometric and textural factors should never be overlooked, as they have an important feedback in the efficiency and feasibility of the industrial treatments (e.g. magnetic separation). Specifically, some Beola varieties with particularly fine grain size and mylonitic texture, are poorly-suited to industrial ore treatments. On the contrary, the Serizzo varieties, although with a generally higher FeOtot content, have a coarser and homogeneous (and therefore preferable) grain size. Waste materials with different composition could be mixed properly until reaching the desired "ideal" compositions for the following industrial treatments. In any case, an accurate characterization of the waste materials from each of quarry dump is of fundamental importance.

  12. The nasal delivery of nanoencapsulated statins – an approach for brain delivery

    Directory of Open Access Journals (Sweden)

    Clementino A

    2016-12-01

    Full Text Available Adryana Clementino,1,2 Mellissa Batger,3 Gabriela Garrastazu,2,3 Michele Pozzoli,3 Elena Del Favero,4 Valeria Rondelli,4 Bianca Gutfilen,5 Thiago Barboza,5 Maria B Sukkar,3 Sergio A L Souza,5 Laura Cantù,4 Fabio Sonvico1,3 1Department of Pharmacy, University of Parma, Parma, Italy; 2National Council for Scientific and Technological Development – CNPq, Brasilia, Brazil; 3Graduate School of Health – Pharmacy, University of Technology Sydney, Ultimo, NSW, Australia; 4Department of Medical Biotechnologies and Translational Medicine, LITA, University of Milan, Segrate, Italy; 5Laboratório de Marcação de Células e Moléculas, Department of Radiology, Faculty of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil Purpose: Along with their cholesterol-lowering effect, statins have shown a wide range of pleiotropic effects potentially beneficial to neurodegenerative diseases. However, such effects are extremely elusive via the conventional oral administration. The purpose of the present study was to prepare and characterize the physicochemical properties and the in vivo biodistribution of simvastatin-loaded lecithin/chitosan nanoparticles (SVT-LCNs suitable for nasal administration in view of an improved delivery of the statins to the brain. Materials and methods: Chitosan, lecithin, and different oil excipients were used to prepare nanocapsules loaded with simvastatin. Particle size distribution, surface charge, structure, simvastatin loading and release, and interaction with mucus of nanoparticles were determined. The nanoparticle nasal toxicity was evaluated in vitro using RPMI 2651 nasal cell lines. Finally, in vivo biodistribution was assessed by gamma scintigraphy via Tc99m labeling of the particles. Results: Among the different types of nanoparticles produced, the SVT-LCN_MaiLab showed the most ideal physicochemical characteristics, with small diameter (200 nm, positive surface charge (+48 mV and high encapsulation

  13. The Dora-Maira Unit (Italian Cottian Alps): a reservoir of ornamental stones locally and worldwide employed since Roman age

    Science.gov (United States)

    Borghi, Alessandro; Cadoppi, Paola; Antonella Dino, Giovanna

    2015-04-01

    marbles, the so called "Rocca Bianca marble" have to be quoted. It has been extensively exploited from the 17th century up to 2003, in two different quarries at an altitude of ca. 2000 m a.s.l. in the Germanasca Valley and the Varaita Valley (Brossasco Marble variety). As regards to Mesozoic carbonate cover, the Foresto and Chianocco white dolomitic marbles have to be cited. They were exploited in the lower Susa Valley and were employed since Roman age (eg. for the construction of the Arch of Augustus at Susa, dating to 9 BC). They were also used during the Renaissance for the façade of the Turin Cathedral. Finally, it must be highlighted the Bargiolina quartzite variety belonging to the Palaeozoic basement: it was known from XVI century (Leonardo Da Vinci wrote about the beauty and the high quality of this material), and was widely employed for historical baroque buildings (palaces and churches). The high number of exploited ornamental and building stones, used over the centuries in local and worldwide historical buildings and infrastructures, allow to think the Dora-Maira Unit as a source of Global Heritage Stones and therefore it could be considered as a Global Heritage Stone Province.

  14. Gneisses (Serizzi and Beole) of the Verbano-Cusio-Ossola district (Piedmont, Northern Italy): possible candidates for the designation of "Global Heritage Stone province"

    Science.gov (United States)

    Antonella Dino, Giovanna; Borghi, Alessandro; Cavallo, Alessandro; Primavori, Piero

    2016-04-01

    The Verbano-Cusio-Ossola quarrying district (Piedmont, northern Italy) produces many different ornamental stones (granites, gneisses, marbles): two really important categories are represented by Serizzo and Beola gneisses. Several varieties of Serizzo and Beola crop out in the upper and middle Ossola Valley: Serizzo derives from the Antigorio, Monte Leone and Monte Rosa Penninic Units, whereas Beola from the Monte Leone, Orselina-Moncucco-Isorno and Monte Rosa Penninic Units, as well from the Fobello-Rimella schists (Austroalpine). The Serizzo, represented by a group of foliated granitoid orthogneisses (Serizzo Antigorio, Serizzo Formazza, Serizzo Sempione and Serizzo Monte Rosa varieties), is probably the most important and extensively exploited ornamental stones from the VCO province (about 70% of the VCO stone production). The quarries are mostly concentrated in the Antigorio and Formazza valleys, where the Antigorio nappe has a sub-horizontal attitude and reaches its greatest thickness (up to 1000 m). This stone was largely used to produce columns since the end of XV century (e.g. the old Ospedale Maggiore in Milano, now University of Milano) and later on it was replaced with granites. It was also used in the building structure of the Duomo di Milano, for the plinth and the piers. Nowadays, thanks to its good wear resistance and low cost, it is mainly used in polished slabs for paving: a recent application is the Frankfurt airport floor. Beola is the name of a group of heterogeneous orthogneisses with mylonitic foliation and strong mineralogical lineation (Beola Grigia, Bianca, Ghiandonata, Striata varieties), easy to split into thin slabs with hammer and chisel, occurring in the middle Ossola Valley, between Vogogna and Montecrestese. The quarries of Beola are probably the oldest of the Ossola Valley, although the precise period in which the stone started to be exported is unknown. The Beola trade probably started at the end of the XIII century, with the

  15. A New Oceanic Anoxic Event 2 record from the Central North Atlantic at South East Newfoundland Ridge, IODP Expedition 342, Newfoundland Drifts

    Science.gov (United States)

    Junium, C. K.; Bornemann, A.; Bown, P. R.; Friedrich, O.; Moriya, K.; Kirtland Turner, S.; Whiteside, J. H.

    2013-12-01

    below the black shale by 60 cm, in the underlying chalk. The temporal transience of TOC-enrichment is typical of OAE 2 sequences, particularly in the Tethyan realm (Gubbio, Italy; Ferriby, UK; Tarfaya, Morocco; Wunsorf, Germany), but the mechanism is unknown. In many ways, Site U1407 bears the distinct characteristics of the Tethyan region. Prior to the OAE, there are several black and dark gray bands interbedded with carbonate-rich (>80 wt. %), greenish white chalks. The color progression of white to black to pink through the OAE at U1407 is similar to C-T boundary sequences from the Umbria-Marche basin of Italy. The greenish white to pink nannofossil chalks are reminiscent of the Scaglia Bianca/Rossa limestones that bound the Bonarelli horizon. Associated lithologies include the presence of radiolarian sands interbedded with the black shales and cherts. This stratigraphic progression is similar to the Italian sequences, but the δ13C stratigraphy indicates that the excursion leads black shale deposition and in this sense is more similar to shallow continental records from the UK, USA and mainland Europe. This new δ13C record can be used to correlate SENR with other OAE 2 sections, allowing us to better understand possible mechanisms for the temporal transience of the black shales and paleoceanographic change during OAE2.

  16. Conference Papers

    International Nuclear Information System (INIS)

    2003-01-01

    A total of 18 papers were presented at the 2003 Annual Executive Conference of the Canadian Gas Association held at St. Andrews, NB, from June 25th to June 28th. Titles of the presentations were as follows: (1) 'Positioning natural gas in a transforming world' by Pierre Marcel Desjardins; (2) 'Positioning natural gas in a transforming world' by Jean-Paul Theoret; (3) 'Perceptions of natural gas' by Noel Sampson; (4) 'Energy efficiency as an opportunity for the natural gas industry' by Peter Love; (5) 'Natural gas R and D - NRCan perspective' by Graham R. Campbell; (6) 'Impact of earned media on corporate perceptions in the gas industry' by Michael Coates; (7) 'Moving forward with an initiative for natural gas technology innovation' by Emmanuel Morin; (8) 'Natural gas R and D - No more dodging the issue' by Chuck Szmurlo; (9) 'Meeting the technology needs of the gas industry and the gas consumer' by Stanley S. Borys; (10) 'Market signals' by John Wellard; (11) 'Future sources of Canadian natural gas' by Rick Hyndman; (12) 'The state of supply: Northeast U.S. perspective' by Tom Kiley; (13) 'AGA's priorities and perspectives' by Dick Reiten; (14) 'Global energy issues: Recent development in policy and business' by Gerald Doucet; (15) 'Keeping the distribution cart behind the horse: Why finding more offshore gas is much more important than completing the natural gas grid, including for New Brunswick' by Brian Lee Crowley; (16) 'Environmental opportunities and challenges for the gas industry' by Manfred Klein; (17) 'The potential for natural gas demand destruction' by Timothy Partridge; and (18) 'Pushing the envelope on gas supply' by Roland R. George. In most instances only speaking notes and view graphs are available

  17. AN OPPORTUNITY SEIZED: J & B SERVICES, INC., THE 1970S AND 1980S DEREGULATION OF THE MOTOR CARRIER SYSTEM, AND THE POTENTIAL FOR SMALL BUSINESS

    Directory of Open Access Journals (Sweden)

    Toby Bates

    2004-01-01

    Full Text Available The mid 1970s and subsequent 1980s witnessed a broad reduction of governmental restraints on the American trucking industry. The reforms initiated in the United States transportation business under the administrations of presidents Gerald Ford, Jimmy Carter and Ronald Reagan accompanied similar and simultaneous moves in telecommunications, airlines, railroads, as well as banking systems. In a ten-year period from roughly 1975 to 1985, and including the passage of the Motor Carrier Act in 1980, the trucking landscape rapidly broadened to include smaller carriers that differed a great deal from their larger predecessors. While all new freight movers did not survive, more than enough succeeded to change forever the organization of the American trucking industry. Structured differently internally and externally, these new smaller carriers carved various economic niches for themselves throughout the United States. Too small to be perceived a threat by the larger companies, and yet too large to be battered by ripples in the national economy, these often locally-owned carriers thrived and grew under the new framework brought about by the deregulation of the trucking industry. Using the Tupelo, Mississippi-based J & B Services, Inc. as a microstudy, this work examines the creation, survival, and expansion of one such carrier in the new economic environment. While the following article does not attempt to solve the debate between the proponents of trucking deregulation and their critics, it does, however, supply enough evidence for the reader to gain brief insight in the American trucking industry, and both sides of the deregulation argument.

  18. A Thermodynamic History of the Solar Constitution — II: The Theory of a Gaseous Sun and Jeans' Failed Liquid Alternative

    Directory of Open Access Journals (Sweden)

    Robitaille P.-M.

    2011-07-01

    Full Text Available In this work, the development of solar theory is followed from the concept that the Sun was an ethereal nuclear body with a partially condensed photosphere to the creation of a fully gaseous object. An overview will be presented of the liquid Sun. A powerful lineage has brought us the gaseous Sun and two of its main authors were the direct sci- entific descendants of Gustav Robert Kirchhoff: Franz Arthur Friedrich Schuster and Arthur Stanley Eddington. It will be discovered that the seminal ideas of Father Secchi and Herv ́ e Faye were not abandoned by astronomy until the beginning of 20th century. The central role of carbon in early solar physics will also be highlighted by revisit- ing George Johnstone Stoney. The evolution of the gaseous models will be outlined, along with the contributions of Johann Karl Friedrich Z ̈ ollner, James Clerk Maxwell, Jonathan Homer Lane, August Ritter, William Thomson, William Huggins, William Edward Wilson, George Francis FitzGerald, Jacob Robert Emden, Frank Washington Very, Karl Schwarzschild, and Edward Arthur Milne. Finally, with the aid of Edward Arthur Milne, the work of James Hopwood Jeans, the last modern advocate of a liquid Sun, will be rediscovered. Jeans was a staunch advocate of the condensed phase, but deprived of a proper building block, he would eventually abandon his non-gaseous stars. For his part, Subrahmanyan Chandrasekhar would spend nine years of his life studying homogeneous liquid masses. These were precisely the kind of objects which Jeans had considered for his liquid stars.

  19. [The development of neurotoxic agents as chemical weapons during the National Socialist period in Germany].

    Science.gov (United States)

    López-Muñoz, F; Alamo, C; Guerra, J A; García-García, P

    The discovery and development of the so-called 'nerve agents' (neurotoxic substances to be used as weapons) took place in the Third Reich, largely thanks to the vast amount of progress being made in pharmacology in Germany at that time, both in academic and industrial terms. Furthermore, successive National Socialist governments set up a collaborative network made up of the academia, the chemical industry and military chiefs that also favoured this line of research. The first neurotoxic substance to be incorporated into the category of 'chemical warfare agent' did so almost wholly by chance. As part of the work being carried out on organophosphate-type pesticides and insecticides, Gerald Schrader, a chemist at the I.G. Farben company, synthesised tabun (ethyl N,N-dimethylphosphoramidocyanidate) and an incident involving accidental contamination of laboratory staff with this substance highlighted its potential toxicity. The same group of researchers later synthesised another substance with the same properties, sarin (isopropyl methylphosphonofluoridate). Both agents were studied for use as chemical weapons by Wolfgang Wirth. At the same time, a group led by Richard Kuhn, who won the Nobel Prize in Chemistry in 1938, synthesised pinacolyl methylphosphonofluoridate, otherwise known as soman. Pharmacological studies confirmed that the neurotoxic mechanism of action of these substances was the irreversible inhibition of the enzyme acetylcholinesterase, which is responsible for metabolising acetylcholine. Results also showed that an excess of this neurotransmitter led to a continuous over-stimulation of the cholinergic (nicotinic and muscarinic) receptors, which is what triggers the appearance of the wide range of symptoms of poisoning and their swift fatal effect.

  20. «Ibernia fabulosa»: per una storia delle immagini dell'Irlanda in Italia

    Directory of Open Access Journals (Sweden)

    Carlo Maria Pellizzi

    2011-08-01

    Full Text Available The essay traces the history of the relations between Italy and Ireland from the 7th century AD to the present. The Irish monks and pilgrims of the Dark Ages brought to the peninsula their hagiographic and legendary writings (such as the Purgatorium Sancti Patricii, which contributed – together with reminiscences from Classical antiquity – to an Italian vision of Ireland as a land of portents and wonders; while after the first Anglo-Norman conquest of the isle the propagandist writings of Gerald of Wales where for centuries the lens through which Ireland was seen in Italy. In the age of the Tudor conquest and Reformation the island slowly lost its fantastic connotations, becoming an asset in the Papal struggle against Anglican England. Later on, in the course of the Italian Risorgimento, the Italian leaders of the movement – such as Mazzini, Cavour, and Cattaneo - generally saw the nationalist movement in Ireland through English eyes, both because of their innate Anglophilia and for reasons of Realpolitik. Only in the 20th century, during WW1 and its aftermath, did Ireland and its national struggle receive in Italy less jaundiced and more sympathetic glances. In the late 1930s and in WW2 the Fascist regime tried to use Ireland as a lever against England; while in the 1970s and 1980s the reemergence of the Anglo-Irish conflict attracted again the interested attention of some sections of the Italian political scene, as did later the ‘peace process’. But through all this the Italian images of Ireland arising from present political realities kept being intertwined with the much older images of centuries gone by.  

  1. Dysgerminoma and ovarian gonadoblastoma in Swyer syndrome

    Directory of Open Access Journals (Sweden)

    Zohreh Yousefi

    2016-06-01

    Full Text Available Background: Swyer syndrome is a type of hypogonadism with 46,XY karyotype. This syndrome was named by Gerald Swyer, an endocrinologist. It leads to a female with normal internal genitalia (uterus, fallopian tubes, cervix, vagina, but instead of ovaries, they have non functional ovary (streak gonads. Also, they have absence of puberty because of gonadal  digenesis. The current practice is to proceed gonadectomy once the diagnosis is made due to the fact that the risk of malignant transformation is high in dysgenetic gonad. In addition, hormonal replacement therapy after surgery is acceptable. Case Presentation: We present a case of gonadoblastom in right ovary in a Swyer syndrome who referred to the department of Gynecology Oncology at Ghaem Hospital, Mashhad University, Iran in 2015 for evaluation of abdomino-pelvic distention. She was a 18-year-old female with 46, XY karyotype and poor secondary sexual character and normal external genitalia. She suffered of abdominal pain. In palpation of the abdomen, an irregular mobile mass was detected in left lower quadrant. The ultrasound revealed uterine size approximate dimensions 3×2 cm (infantile and a 19 cm pelvic mass heterogeneous and multi-loculated in left side of the pelvic cavity with possible origin of the left ovary. In addition, in right pelvic fossa, a mass about 6 cm was detected. CT-Scan showed a pelvic mass with overall dimensions of 10 cm with vicinity to the left iliac vessels, modest amounts of ascities along with evidence of peritoneal dissemination (seeding. In laparotomy we observed massive ascities and a 20 cm solid mass in left ovary and a small mass in right ovary and involvement para aortic lymph node. Pathological report indicated as stage III of dysgerminoma in left ovary and gonadoblastom in right ovary. Conclusion: This case is presented because it could have excellent prognosis if not missed opportunities of early recognizing and furthermore adequate treatment with

  2. Reconnaissance of the Manistee River, a cold-water river in the northwestern part of Michigan's Southern Peninsula

    Science.gov (United States)

    Hendrickson, G.E.; Doonan, C.J.

    1972-01-01

    The cold-water streams of the northern states provide unique recreational values to the American people (wilderness or semi-wilderness atmosphere, fast-water canoeing, trout fishing), but expanding recreational needs must be balanced against the growing demand of water for public and industrial supplies, irrigation, and dilution of sewage and other wastes. In order to make intelligent decisions regarding use and management of water resources for recreation and other demands, an analysis of hydrologic factors related to recreation is essential.The Manistee River is one of Michigan's well-known trout streams-a stream having numerous public access sites and campgrounds. Upstream from Cameron Bridge (see location map) the Manistee is rated as a first-class trout stream but below Cameron Bridge the river is rated only as a fair trout stream by the Michigan Department of Natural Resources. As a Michigan canoe trail it is second only to the Au Sable River in popularity. Esthetically, the Manistee is one of Michigan's most attractive rivers, its waters flowing cool and clean, and around each bend a pleasant wilderness scene. This report deals with that part of the river upstream from State Highway M-66 at Smithville. Several hard-surface roads give access to the upper river as shown on the location map. Numerous dirt roads and trails give access to the river at intermediate points. The recreational values of the Manistee depend on its characteristics of streamflow, water quality, and bed and banks. This atlas describes these characteristics and shows how they relate to recreational use.Much of the information presented here was obtained from basic records of the U.S. Geological Survey's Water Resources Division. Additional information was obtained from field reconnaissance surveys in 1968 and 1969. The study was made in cooperation with the Michigan Geological Survey, Gerald E. Eddy, Chief. Assistance was also obtained from other sections of the Michigan Department of

  3. Contemporary musical historiography and the problems of the methodological approach

    Directory of Open Access Journals (Sweden)

    Vasić Aleksandar N.

    2005-01-01

    Full Text Available The first foreign review of the general history of music translated to Serbian language was Karl Nef's Einführung in die Musikgeschichte. It was published in Belgrade, in 1937. During the '70s and '80s of the 20th century, there were translated popularly conceived histories of music of Luciano Alberti and Nobert Difourc. In 2002/2004 the Belgrade publisher "Clio" issued the second and third volume of Gerald Abraham's Concise Oxford History of Music. It was estimated that the long pause, as well as the choice of the prominent British author, present strong reasons for detailed critical study approach to the latest edition. The character of the study is threefold and interdisciplinary: musicological, philological and bibliographical. The first part of the study is the analysis of the writer's methodological procedure that can be discussed. Namely, next to the significant virtues in expert and style such as conciseness in statements original observations and evaluations, and literate, aesthetic attractiveness, Abraham's book also contains contradictory of methodological character. The writer is not completely consistent in conducting of the chosen methodological procedure. On one side, he does not describe the history of European music with period terms such as baroque, classicism impressionism or expressionism. On the other side, he nevertheless uses period terms in some way, but only in relation to the music of the 19th century. The only style that The Concise Oxford History of Music elaborates is Romanticism. Such inconsistent ness cannot be justified even more from the aspect of potential student readers of this reference book. The second part of disquisition contains analysis and evaluation of the Serbian translation of Abraham's History. That philological section of the work discusses mistakes in translation, controversial examples of transcription and adaptation of foreign names, grammatical, lexical and punctuation omissions. Also

  4. 150 Years of the American Nautical Almanac Office

    Science.gov (United States)

    Dick, S. J.

    1999-05-01

    In 1849, 50 years before the founding of the American Astronomical Society, the American Nautical Almanac Office was established in Cambridge, Massachusetts. Although the British had published a Nautical Almanac since 1767, both patriotic and practical reasons lay behind the founding of an American Nautical Almanac Office in the context of the growth of science in the United States. Lt. Charles Henry Davis served as the first Superintendent. In 1866 the Office moved to Washington, D. C., and beginning in 1893 it was physically located at the new (present) site of the U. S. Naval Observatory, of which it became a part over the next few years, and where it has since remained. >From its beginning the work of the Office was much broader than the publication of data for navigation. The Office also sought to improve the theories of motion of the Sun, Moon and planets, and the astronomical constants on which the Almanac was based. Under Simon Newcomb, Superintendent of the Office from 1877 until his retirement in 1897, a consistent system of constants was devised; some of these constants remained unchanged until 1984. The American Nautical Almanac Office was dominated before World War II by its Directors William S. Eichelberger (1910-1929) and A. James Robertson (1929-1939). During the War years Wallace J. Eckert introduced punched card techniques to the Office. Gerald Clemence used these techniques to improve planetary theories during his years as Director (1945-1958), and also ushered in the era of the electronic computer for both research and production. International collaboration was a hallmark of the tenures of Clemence, Edgar Woolard, Raynor Duncombe and P. K. Seidelmann, who also implemented changes necessitated by the Space Age. Since 1990 the Nautical Almanac Office has been part of the Astronomical Applications Department of the Naval Observatory.

  5. Treatment approaches and adherence to urate-lowering therapy for patients with gout

    Directory of Open Access Journals (Sweden)

    Aung T

    2017-04-01

    Full Text Available Thanda Aung,* Gihyun Myung,* John D FitzGerald Division of Rheumatology/Department of Internal Medicine, University of California, Los Angeles, Los Angeles, CA, USA *These authors contributed equally to this work Abstract: Gout is the most common inflammatory arthritis characterized by painful disabling acute attacks. It is caused by hyperuricemia and deposition of urate crystals in and around the joints. Long-standing untreated hyperuricemia can lead to chronic arthritis with joint damage, tophi formation and urate nephropathy. Gout is associated with significant morbidity and health care associated cost. The goal of long-term therapy is to lower the serum urate level to promote dissolution of urate crystals, reduce recurrent acute gout flares, resolve tophi and prevent joint damage. Despite the presence of established gout treatment guidelines and effective medications to manage gout, patient outcomes are often poor. Etiology for these shortcomings is multifactorial including both physician and patient characteristics. Poor adherence to urate-lowering therapy (ULT is prevalent and is a significant contributor to poor patient outcomes. This article reviews the treatment strategies for the management of hyperuricemia in chronic gout, gaps in quality of care in gout management, factors contributing to poor adherence to ULT and discusses potential interventions to achieve improved gout-related outcomes. These interventions include initiation of prophylactic anti-inflammatory medication when starting ULT, frequent follow-ups, regular serum urate monitoring and improved patient education, which can be achieved through pharmacist- or nurse-assisted programs. Interventions such as these could improve adherence to ULT and, ultimately, result in optimal gout-related outcomes. Keywords: gout, adherence, urate-lowering therapy 

  6. Prophesying Women and Ruling Men: Women’s Religious Authority in North American Pentecostalism

    Directory of Open Access Journals (Sweden)

    Lisa P. Stephenson

    2011-08-01

    Full Text Available The issue of religious authority is one of the main reasons why women have been allowed to participate in Pentecostal churches, and why they have been limited. Women are granted access to ministering authority, but not governing authority. Charles Barfoot and Gerald Sheppard have noted the presence of these two types of authority to be operative within Pentecostalism and have associated them with Max Weber’s typology of prophet and priest. However, in their attempt to describe the history of Pentecostal women in ministry with these categories, Barfoot and Sheppard present the paradigm as one of displacement rather than coexistence. The result is a problematic and misleading account of Pentecostal women in ministry. However, the issue is not Weber’s categories, but how they employ them. The purpose of this article is to utilize the distinction between prophet and priest to differentiate between two types of ecclesial functions and their concomitant religious authority, rather than to differentiate between two periods of Pentecostalism. A brief history of Pentecostal women in ministry is presented, wherein examples are offered of how women in the Church of God, the Church of God in Christ, the Assemblies of God, and the International Church of the Foursquare Gospel operated in the prophetic realms with a ministering authority, but were largely prohibited from the priestly realms and its ruling authority. As these examples demonstrate, the history of Pentecostal women in ministry is told best when the simultaneous existence of the prophetic and priestly functions are recognized, and ministering authority and ruling authority are connected to these two functions.

  7. Serum-derived bovine immunoglobulin/ protein isolate: postulated mechanism of action for management of enteropathy

    Directory of Open Access Journals (Sweden)

    Petschow BW

    2014-05-01

    Full Text Available Bryon W Petschow, Bruce Burnett, Audrey L Shaw, Eric M Weaver, Gerald L Klein Entera Health, Inc., Cary, NC, USA Abstract: The health and performance of the gastrointestinal tract is influenced by the interaction of a variety of factors, including diet, nutritional status, genetics, environment, stress, the intestinal microbiota, immune status, and gut barrier. Disruptions in one or more of these factors can lead to enteropathy or intestinal disorders that are known to occur in concert with certain disease states or conditions such as irritable bowel syndrome or human immunodeficiency virus (HIV infection. Nutritional support in the form of a medical food along with current therapies could help manage the adverse effects of enteropathy, which include effects on nutrient digestion, absorption, and metabolism, as well as utilization of nutrients from foodstuffs. Numerous studies have demonstrated that oral administration of plasma- or serum-derived protein concentrates containing high levels of immunoglobulins can improve weight management, normalize gut barrier function, and reduce the severity of enteropathy in animals. Recent trials in humans provide preliminary evidence that a serum-derived bovine immunoglobulin/protein isolate is safe and improves symptoms, nutritional status, and various biomarkers associated with enteropathy in patients with HIV infection or diarrhea-predominant irritable bowel syndrome. This review summarizes data from preclinical and clinical studies with immunoglobulin-containing plasma/serum protein concentrates, with a focus on the postulated mode of action of serum-derived bovine immunoglobulin/protein isolate for patients with enteropathy. Keywords: bovine immunoglobulins, nutrient, gut barrier, microbiota

  8. An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid as a permeation enhancer

    Directory of Open Access Journals (Sweden)

    Mooranian A

    2014-09-01

    Full Text Available Armin Mooranian,1 Rebecca Negrulj,1 Nigel Chen-Tan,2 Gerald F Watts,3 Frank Arfuso,4 Hani Al-Salami11Biotechnology and Drug Development Research Laboratory, School of Pharmacy, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, 2Faculty of Science and Engineering, Curtin University, 3School of Medicine and Pharmacology, Royal Perth Hospital, University of Western Australia, 4School of Biomedical Science, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, Perth, AustraliaAbstract: The authors have previously designed, developed, and characterized a novel microencapsulated formulation as a platform for the targeted delivery of therapeutics in an animal model of type 2 diabetes, using the drug probucol (PB. The aim of this study was to optimize PB microcapsules by incorporating the bile acid deoxycholic acid (DCA, which has good permeation-enhancing properties, and to examine its effect on microcapsules’ morphology, rheology, structural and surface characteristics, and excipients’ chemical and thermal compatibilities. Microencapsulation was carried out using a BÜCHI-based microencapsulating system established in the authors’ laboratory. Using the polymer sodium alginate (SA, two microencapsulated formulations were prepared: PB-SA (control and PB-DCA-SA (test at a constant ratio (1:30 and 1:3:30, respectively. Complete characterization of the microcapsules was carried out. The incorporation of DCA resulted in better structural and surface characteristics, uniform morphology, and stable chemical and thermal profiles, while size and rheological parameters remained similar to control. In addition, PB-DCA-SA microcapsules showed good excipients’ compatibilities, which were supported by data from differential scanning calorimetry, Fourier transform infrared spectroscopy, scanning electron microscopy, and energy dispersive X-ray studies, suggesting

  9. Milnacipran: a unique antidepressant?

    Directory of Open Access Journals (Sweden)

    Siegfried Kasper

    2010-08-01

    Full Text Available Siegfried Kasper, Gerald PailDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, AustriaAbstract: Tricyclic antidepressants (TCAs are among the most effective antidepressants available, although their poor tolerance at usual recommended doses and toxicity in ­overdose make them difficult to use. While selective serotonin reuptake inhibitors (SSRIs are ­better tolerated than TCAs, they have their own specific problems, such as the aggravation of sexual dysfunction, interaction with coadministered drugs, and for many, a discontinuation syndrome. In addition, some of them appear to be less effective than TCAs in more severely depressed patients. Increasing evidence of the importance of norepinephrine in the etiology of depression has led to the development of a new generation of antidepressants, the serotonin and ­norepinephrine reuptake inhibitors (SNRIs. Milnacipran, one of the pioneer SNRIs, was designed from theoretic considerations to be more effective than SSRIs and better tolerated than TCAs, and with a simple pharmacokinetic profile. Milnacipran has the most balanced potency ratio for reuptake inhibition of the two neurotransmitters compared with other SNRIs (1:1.6 for milnacipran, 1:10 for duloxetine, and 1:30 for venlafaxine, and in some studies milnacipran has been shown to inhibit norepinephrine uptake with greater potency than serotonin (2.2:1. Clinical studies have shown that milnacipran has efficacy comparable with the TCAs and is superior to SSRIs in severe depression. In addition, milnacipran is well tolerated, with a low potential for pharmacokinetic drug–drug interactions. Milnacipran is a first-line therapy suitable for most depressed patients. It is frequently successful when other treatments fail for reasons of efficacy or tolerability.Keywords: milnacipran, SNRI, antidepressant efficacy, tolerability

  10. Monoaminergic Control of Cellular Glucose Utilization by Glycogenolysis in Neocortex and Hippocampus.

    Science.gov (United States)

    DiNuzzo, Mauro; Giove, Federico; Maraviglia, Bruno; Mangia, Silvia

    2015-12-01

    Brainstem nuclei are the principal sites of monoamine (MA) innervation to major forebrain structures. In the cortical grey matter, increased secretion of MA neuromodulators occurs in response to a wealth of environmental and homeostatic challenges, whose onset is associated with rapid, preparatory changes in neural activity as well as with increases in energy metabolism. Blood-borne glucose is the main substrate for energy production in the brain. Once entered the tissue, interstitial glucose is equally accessible to neurons and astrocytes, the two cell types accounting for most of cellular volume and energy metabolism in neocortex and hippocampus. Astrocytes also store substantial amounts of glycogen, but non-stimulated glycogen turnover is very small. The rate of cellular glucose utilization in the brain is largely determined by hexokinase, which under basal conditions is more than 90 % inhibited by its product glucose-6-phosphate (Glc-6-P). During rapid increases in energy demand, glycogen is a primary candidate in modulating the intracellular level of Glc-6-P, which can occur only in astrocytes. Glycogenolysis can produce Glc-6-P at a rate higher than uptake and phosphorylation of glucose. MA neurotransmitter are released extrasinaptically by brainstem neurons projecting to neocortex and hippocampus, thus activating MA receptors located on both neuronal and astrocytic plasma membrane. Importantly, MAs are glycogenolytic agents and thus they are exquisitely suitable for regulation of astrocytic Glc-6-P concentration, upstream substrate flow through hexokinase and hence cellular glucose uptake. Conforming to such mechanism, Gerald A. Dienel and Nancy F. Cruz recently suggested that activation of noradrenergic locus coeruleus might reversibly block astrocytic glucose uptake by stimulating glycogenolysis in these cells, thereby anticipating the rise in glucose need by active neurons. In this paper, we further develop the idea that the whole monoaminergic system

  11. Information, communication and education on climate change. European perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Filho, W.L.; Mannke, F. [TuTech Innovation GmbH, Hamburg (Germany); Schmidt-Thome, P. (eds.) [Geologinen Tutkimuslaitos, Espoo (Finland)

    2007-07-01

    It is now beyond any doubt that climate change represents a major threat to the environmental, social and economic well being of the planet. The book under consideration is an attempt to contribute to the global debate on climate change by outlining some educational methods, approaches and projects which have been focusing on climate issues in Europe. The book under consideration consists of the following chapters: (a) ESPACE - A New Transnational Approach to Adapting to the Impacts of Climate Change (Jill Cook, Doogie Black, Angela Bentham, Tania Stadsbader, Jorn Peters, Lesley van Dijk, Mark Goldthorpe, Tim Yair, Fran Wallington, Meinte de Hoogh, Michael Belau); (b) Communicating Climate Change Impacts - an Approach Derived from two Regional Development Projects (Philipp Schmidt-Thome, Johannes Klein); (c) Baltex Assessment of Climate Change for the Baltic Sea Basin (BACC) (Hans von Storch, Anders Omstedt, Hans-Joerg Isemer); (d) Promoting Climate friendly Communities in Northamptonshire, United Kingdam (Philip Gray, Shane Conway); (e) Climite Change Mitigation and Sustainability: Educational Issues (Remigijus Ciegis; Dalia Streimikiene, Dalia Gineitiene); (f) Case Study Research as Bridge Builder between Science and the Society - The Rationale behind the ASTRA 2005 Winter Storm Study (Simo Haanpaeae, Lasse Peltonen); (g) Educational Actions in Italy to face the Problem of Climate Change (Eugenia Aloj, Mariagrazia De Castro, Anna Zollo); (h) Teaching Global Climate Change as a Controversial Issue - Active Learning in Higher Education (Evangelos I. Manolas); (i) Regional Climate Change and Coasts - A Case Study on Perception, Information, Dissemination and Education (Gerald Schernewski, Steffen Bock, Holger Janssen, Nardine Loeser, Annemone Himielorz); (j) KLARA-Net: An Interdisciplinary Action Oriented Approach on Climate Change Adaptation (Birte Frommer; Lena Herlitzius); (k) Climate Change, Featuring the ACCROTELM Project: Dissemination of a European RTD

  12. Ernst Mach and George Sarton's Successors: The Implicit Role Model of Teaching Science in USA and Elsewhere, Part II

    Science.gov (United States)

    Siemsen, Hayo

    2013-05-01

    George Sarton had a strong influence on modern history of science. The method he pursued throughout his life was the method he had discovered in Ernst Mach's Mechanics when he was a student in Ghent. Sarton was in fact throughout his life implementing a research program inspired by the epistemology of Mach. Sarton in turn inspired many others in several generations (James Conant, Thomas Kuhn, Gerald Holton, etc.). What were the origins of these ideas in Mach and what can this origin tell us about the history of science and science education nowadays? Which ideas proved to be successful and which ones need to be improved upon? The following article will elaborate the epistemological questions, which Charles Darwin's "Origin" raised concerning human knowledge and scientific knowledge and which led Mach to adapt the concept of what is "empirical" in contrast to metaphysical a priori assumptions a second time after Galileo. On this basis Sarton proposed "genesis and development" as the major goal of his journal Isis. Mach had elaborated this epistemology in La Connaissance et l'Erreur ( Knowledge and Error), which Sarton read in 1911 (Hiebert in Knowledge and error. Reidel, Dordrecht, 1976; de Mey in George Sarton centennial. Communication & Cognition, Ghent, pp. 3-6, 1984). Accordingly for Sarton, history becomes not only a subject of science, but a method of science education. Culture—and science as part of culture—is a result of a genetic process. History of science shapes and is shaped by science and science education in a reciprocal process. Its epistemology needs to be adapted to scientific facts and the philosophy of science. Sarton was well aware of the need to develop the history of science and the philosophy of science along the lines of this reciprocal process. It was a very fruitful basis, but a specific part of it Sarton did not elaborate further, namely the erkenntnis-theory and psychology of science education. This proved to be a crucial missing

  13. Post-mining water treatment. Nanofiltration of uranium-contaminated drainage. Experiments and modeling

    International Nuclear Information System (INIS)

    Hoyer, Michael

    2017-01-01

    Nanofiltration of real uranium-contaminated mine drainage was successfully discussed in experiments and modeling. For the simulation a renowned model was adapted that is capable of describing multi-component solutions. Although the description of synthetic multi-component solutions with a limited number of components was performed before ([Garcia-Aleman2004], [Geraldes2006], [Bandini2003]) the results of this work show that the adapted model is capable of describing the very complex solution. The model developed here is based on: The Donnan-Steric Partitioning Pore Model incorporating Dielectric Exclusion - DSPM and DE ref. [Bowen1997], [Bandini2003], [Bowen2002], [Vezzani2002]. The steric, electric, and dielectric exclusion model - SEDE ref. [Szymczyk2005]. The developed modeling approach is capable of describing multi-component transport, and is based on the pore radius, membrane thickness, and volumetric membrane charge density as physically relevant membrane parameters instead of mere fitting parameters which allows conclusions concerning membrane modification or process design. The experiments involve typical commercially available membranes in combination with a water sample of industrial relevance in the mining sector. Furthermore, it has been shown experimentally that uranium speciation influences its retention. Hence, all experiments consider the speciation of uranium when assessing its charge and size. In the simulation 10 different ionic components have been taken into account. By freely fitting 4 parameters in parallel (pore radius, membrane thickness, membrane charge, relative permittivity of the oriented water layer at the pore wall) an excellent agreement between experiment and simulation was obtained. Moreover, the determined membrane thickness and pore radius is in close agreement with the values obtained by independent membrane characterization using pure water permeability and glucose retention. On the other hand, the fitted and the literature

  14. Slides with no attached paper

    International Nuclear Information System (INIS)

    Warin, Dominique; Wallenius, Janne; Ouzounian, Gerald; Wikberg, Peter; Todd, Terry A.; Kormilitsyn, Mikhael V.; Osipenko, Alexander G.; Mayorshin, A.A.; McLachlan, Fiona; Nash, Ken L.; Nilsson, M.; Grimes, T.; Braley, J.C.; TAKESHITA, Kenji; Babain, Vasiliy A.; Spendlikova, I.; Distler, P.; John, J.; Sebesta, F.; VU, Trong-Hung; SIMONIN, Jean-Pierre; PAULENOVA, Alena; PRECEK, Martin; HARTIG, Kyle; KNAPP, Nathan; Vidick, Geoffrey; Bouslimani, Nouri; Desreux, Jean F.; Lewis, F.W.; Hudson, M.J.; Harwood, L.M.; Nunez, Ana; Nagarajan, K.; Vasudeva Rao, P.R.; Raj, Baldev; Ignatiev, Victor; Surenkov, Alexander; Pouchon, Manuel A.; Skarnemark, Gunnar; Allard, Stefan; Ekberg, Christian; Retegan, Teodora; Nordlund, Anders; John, Jan; Maershin, Alexander; Zakirov, R.; Panov, A.; Toropov, Andrey

    2010-01-01

    This document brings together the different presentations (slides) given at the workshop but with no attached paper. These slides refer to the following presentations: - Presentation of ITN (Instituto Tecnologico e Nuclear); - Minor Actinide Partitioning (Dominique Warin); - Transmutation (Janne Wallenius); - Radioactive Waste Management, IGD-TP (Gerald Ouzounian); - Present status of the Swedish nuclear waste management programme (Peter Wikberg); - The U.S. Fuel Cycle Research and Development Program - Separations Research and Development (Terry Todd); - Strategies and national programs of closed fuel cycles - Russian Expert Vision (Mikhael Kormilitsyn) - Extraction Studies Of Potential Solvent Formulations For The GANEX Process (Fiona MacLachlan); - Investigations of The Fundamental Chemistry of the TALSPEAK Process (Ken Nash); - Extraction Separation of Trivalent Minor Actinides and Lanthanides by Hexa-dentate Nitrogen-donor Extractant, TPEN, and its Analogs (Kenji Takeshita); - Fluorinated Diluents for HLW Processing - technological point of view (Vasiliy Babain); - Extraction properties of some new pyridine molecules and search for better diluents (Irena Spendlikova); - Kinetics of extraction of Eu 3+ ion by TODGA and CyMe 4 -BTBP studied using the RMC technique (Trong Hung Vu); - Redox Chemistry of Neptunium in Solutions of Nitric Acid (Alena Paulenova); - NMR applied to actinide ions and their complexes. In search of covalency effects (Geoffrey Vidick); - Towards 'Stability Rules' for Radiolysis of bis-DGA compounds (Ana Nunez); - Pyroprocess Research Activities at IGCAR, Kalpakkam, India (K. Nagarajan); - Critical issues of nuclear energy systems employing molten salt fluorides: from ISTC No. 1606 to No. 3749 (1. year of project activity) and MARS/EVOL cooperation (Victor Ignatiev); - Conversion processes: Internal Gelation and the Sphere-pac concept (Manuel Pouchon); - A Combined Nuclear Technology and Nuclear Chemistry Master. A Unique

  15. Radiolabelled leucocyte scintigraphy versus conventional radiological imaging for the management of late, low-grade vascular prosthesis infections.

    Science.gov (United States)

    Erba, P A; Leo, G; Sollini, M; Tascini, C; Boni, R; Berchiolli, R N; Menichetti, F; Ferrari, M; Lazzeri, E; Mariani, G

    2014-02-01

    In this study we evaluated the diagnostic performance of (99m)Tc-HMPAO-leucocyte ((99m)Tc-HMPAO-WBC) scintigraphy in a consecutive series of 55 patients (46 men and 9 women, mean age 71 ± 9 years, range 50 - 88 years) with a suspected late or a low-grade late vascular prosthesis infection (VPI), also comparing the diagnostic accuracy of WBC with that of other radiological imaging methods. All patients suspected of having VPI underwent clinical examination, blood tests, microbiology, US and CT, and were classified according to the Fitzgerald criteria. A final diagnosis of VPI was established in 47 of the 55 patients, with microbiological confirmation after surgical removal of the prosthesis in 36 of the 47. In the 11 patients with major contraindications to surgery, the final diagnosis was based on microbiology and clinical follow-up of at least 18 months. (99m)Tc-HMPAO-WBC planar, SPECT and SPECT/CT imaging identified VPI in 43 of 47 patients (20 of these also showed infection at extra-prosthetic sites). In the remaining eight patients without VPI, different sites of infections were found. The use of SPECT/CT images led to a significant reduction in the number of false-positive findings in 37% of patients (sensitivity and specificity 100 %, versus 85.1% and 62.5% for stand-alone SPECT). Sensitivity and specificity were 34% and 75% for US, 48.9% and 83.3% for CT, and 68.1% and 62.5% for the FitzGerald classification. Perioperative mortality was 5.5%, mid-term mortality 12%, and long-term mortality 27%. Survival rates were similar in patients treated with surgery and antimicrobial therapy compared to patients treated with antimicrobial therapy alone (61% versus 63%, respectively), while infection eradication at 12 months was significantly higher following surgery (83.3% versus 45.5%). (99m)Tc-HMPAO-WBC SPECT/CT is useful for detecting, localizing and defining the extent of graft infection in patients with late and low-grade late VPI with inconclusive

  16. From cold power strategies to hot wars about raw materials? Game of chess of the world power between preventive war and futurable raw material politics in the age of the greenhouse; Von kalten Energiestrategien zu heissen Rohstoffkriegen? Schachspiel der Weltmaechte zwischen Praeventivkrieg und zukunftsfaehiger Rohstoffpolitik im Zeitalter des globalen Treibhauses

    Energy Technology Data Exchange (ETDEWEB)

    Roithner, T. (comp.)

    2008-07-01

    The 24th international summer academy, held in Stadtschlaining (Burgenland, Austria) between 8th July and 13th July, 2007, is engaged with the reasons to the conflicts and military conflicts at the end of the fossil energy age. The following lectures are held: (a) From cold power strategies to hot wars about raw materials? (Thomas Roithner); (b) Inauguration of the 24th international summer academy 2007 (Gerald Mader); (c) A change of consciousness also changes unconsciously the being (Hans Lukits); (d) Oil in fire - Conflicts of resources as a fuel for global discord (Wolfgang Sachs); (e) Safety discourses on both sides of the Atlantic - in times o peak oil and climatic change (Elmar Altvater); (f) From energy security to the war of resources: the resource politics of China, Russia and India (Andreas Zumach); (g) Why is there no alternative to the retreat from Afghanistan? (Peter Strutynski); (h) Do ''Peak Oil'' and nuclear energy solve the climate problem? (Helga Kromp-Kolb, Wolfgang kromp); (i) Water - the material from that conflicts consist? (Juerg Staudenmann, Karin Scheurer); (j) US strategy for the regions of Middle East and Caucasus in the unipolar world order (Matin Baraki); (k) What are the influences of oil on the conflict with Iran? (Udo Steinbach); (l) Geopolicy and resources: The grasp of the USA at Africa (Werner Ruf); (m) New colonization of Africa: China, USA and Europe in the struggle for resources (Karin Kneissl); (n) Securing resources and energy politics in Latin America: US politics, EU politics or independent world politics (Peter Stania); (o) More scarcely becoming raw materials - a source for armament and war planning? (Luehr Henken); (p) Battle groups - intervening groups for securing resources (Gunther Hauser); (q) Organization of the globalization as fateful question - which future lies before us? (Franz-Josef Radermacher); (r) No peace without change of renewable resources (Hermann Scheer); (s) Peaceable, forced or

  17. Assessing the effect of culturally specific audiovisual educational interventions on attaining self-management skills for chronic obstructive pulmonary disease in Mandarin- and Cantonese-speaking patients: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Poureslami I

    2016-08-01

    Full Text Available Iraj Poureslami,1,2 Susan Kwan,3 Stephen Lam,4,5 Nadia A Khan,6,7 John Mark FitzGerald 8,9 1Respiratory Division, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada; 2Department of Graduate Studies, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Vancouver, Canada; 3Respiratory Department, Burnaby Hospital, University of British Columbia, Burnaby, Canada; 4Respiratory Division, University of British Columbia, Vancouver, Canada; 5Department of Integrative Oncology, BC Cancer Research Centre, Vancouver, Canada; 6Department of Internal Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada; 7Department of Internal Medicine, Providence Health Care Authority, Vancouver, Canada; 8VGH Divisions of Respiratory Medicine, University of British Columbia, Vancouver, Canada; 9Respiratory Medicine, Vancouver Coastal Health Authority, Vancouver Coastal Health Research Institute, Institute for Heart and Lung Health, The Lung Centre, Gordon and Leslie Diamond Health Care Centre, Vancouver, Canada Background: Patient education is a key component in the management of chronic obstructive pulmonary disease (COPD. Delivering effective education to ethnic groups with COPD is a challenge. The objective of this study was to develop and assess the effectiveness of culturally and linguistically specific audiovisual educational materials in supporting self-management practices in Mandarin- and Cantonese-speaking patients. Methods: Educational materials were developed using participatory approach (patients involved in the development and pilot test of educational materials, followed by a randomized controlled trial that assigned 91 patients to three intervention groups with audiovisual educational interventions and one control group (pamphlet. The patients were recruited from outpatient clinics. The primary outcomes were improved inhaler technique and

  18. Parkinson's disease and the quest for preclinical diagnosis: an interview with Professor Werner Poewe.

    Science.gov (United States)

    Poewe, Werner

    2017-10-01

    Werner Poewe speaks to Laura Dormer, Editorial Director: Professor Werner Poewe is Professor of Neurology and Director of the Department of Neurology at Innsbruck Medical University in Innsbruck, Austria. He held a Residency in Clinical Neurology and Psychiatry at the University of Innsbruck, Austria, from 1977 to 1984. From 1984 to 1985 he teamed up with Gerald Stern and Andrew Lees as a British Council Research Fellow at University College and Middlesex Hospital's Medical School in London to perform clinical studies into levodopa-induced dystonia and pharmacokinetics of levodopa in naive versus L-Dopa treated Parkinson's disease. Following his return to Austria, he held a position as Senior Lecturer in the Department of Neurology at the University of Innsbruck (1986-1989) after which he took over as Professor of Neurology and Acting Director of the Department of Neurology at Virchow Hospital of the Free University of Berlin (1990-1994). Professor Poewe's main research interests in the field of movement disorders are focused on differential and early diagnosis of Parkinson's disease, its natural history and pharmacological treatment. He has been involved in the steering committees of numerous drug trials in different stages of Parkinson's disease for the past 20 years and has authored and coauthored more than 500 original articles and reviews in the field of movement disorders. Professor Poewe served as President of the Austrian Society of Neurology from 2002 to 2004 as well as President of the Austrian Parkinson's Disease Society from 1996 to 2009. He has been awarded honorary membership of the German Society of Neurology as well as the Japanese Society of Neurology. His awards include the Walther-Birkmayer-Prize of the Austrian PD Society, the Dingebauer-Prize of the German Neurological Society as well as the Research Excellence Award of Innsbruck Medical University. Professor Poewe served as President of the International Movement Disorder Society (MDS) from

  19. Resistência Cultural, Gênero, Raça e Sexualidade em Cuba e no Brasil, entrevista com Tanya Saunders

    Directory of Open Access Journals (Sweden)

    Sheila dos Santos Nascimento

    2017-06-01

    Full Text Available Em 2016, por ocasião do Dia Internacional da Mulher Negra Latino Americana e Caribenha, comemorado em 25 de Julho, as ativistas lésbicas Sheila Nascimento (Coletivo LGBTSol e Bárbara Alves (Lesbibahia receberam nas dependências do Grupo de Estudos Feministas em Política e Educação (GIRA da Faculdade de Filosofia e Ciências Humanas (FFCH da Universidade Federal da Bahia (UFBA a Profa. Tanya Saunders da Universidade da Flórida. Tanya Saunders é PHD em Sociologia pela Universidade de Michigan; e mestre em Política e Desenvolvimento Internacional do Gerald R. Ford, Escola de Políticas Públicas. Dentre seus interesses de pesquisa, vale ressaltar, a sua busca pelo aprofundamento no conhecimento acerca do ativismo no campo das artes, ou Artivismo, na Diáspora Africana nas Américas, inserindo os debates em torno das identidades sociais de raça, gênero e sexualidade.Tanya Saunders, que esteve no Brasil como professora visitante no Programa de Pós-Graduação em Estudos Interdisciplinares sobre Gênero, Mulheres e Feminismos (PPGNEIM na linha de pesquisa Gênero, Arte e Cultura, realizou trabalho de campo sobre os movimentos sociais brasileiros baseados em artes urbanas e nos movimentos de educação alternativa. Nessa entrevista a docente apresenta sua trajetória como pesquisadora nos estudos sobre raça, gênero e sexualidade, culminando com sua proposta de uma Teoria Queer de Base, cuja gênese se deu a partir de seu trabalho de campo com mulheres negras lésbicas em Cuba e no Brasil. Segundo a pesquisadora os estudos interdisciplinares em raça, gênero, sexualidade e arte possibilitam a compreensão de novas formas de resistência ao racismo, sexismo e lesbofobia. Aponta também para seu interesse em pensar a teoria negra brasileira e possíveis redes de pesquisa e ativismo entre o Caribe, a América Latina e os Estados Unidos.

  20. The REDIH experience: an emerging design to develop an effective training program for graduate students in reproductive science

    Directory of Open Access Journals (Sweden)

    MacDonald CJ

    2013-10-01

    Full Text Available Colla J MacDonald,1 Douglas Archibald,2 Jay M Baltz,3 Gerald M Kidder4 1Faculty of Education, 2Department of Family Medicine, University of Ottawa, Ottawa, ON, Canada; 3Ottawa Hospital Research Institute, Ottawa, ON, Canada; 4Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada Background: A training program in Reproduction, Early Development, and the Impact on Health (REDIH was initiated in 2009 by researchers specializing in biomedical, clinical, population health, and ethics research from seven collaborating universities in Quebec and Ontario, and Health Canada. This paper reports the findings from the first three years of the 6-year program. Objectives: The objective of the REDIH program is to provide increased opportunities for excellent training in reproduction and early development for graduate students and fellows, in order to build research, clinical, regulatory, decision-making, and industry capacity in Canada. Methods: A mixed methods approach was used to evaluate the REDIH training program, so as to combine the strengths of both qualitative and quantitative studies. A total of four focus groups (two with mentors and two with trainees were run during the June 2012 REDIH meeting. Surveys were administered directly after each training module. The W(eLearn framework was used as a guide to design and evaluate the program and answer the research questions. Results: The data from the analysis of the focus group interviews, in corroboration with the survey data, suggested trainees enjoyed and benefited from the REDIH experience. Trainees provided several examples of new knowledge and skills they had acquired from REDIH sessions, regarding reproductive and early developmental biology, and health. A few trainees who had been in the program for over a year provided examples of knowledge and skills acquired during the REDIH session that they were using in their place of work. Next steps will include

  1. Delayed hyperacute rejection in a patient who developed clostridium difficile infection after ABO-incompatible kidney transplantation

    Directory of Open Access Journals (Sweden)

    Gerald S Lipshutz

    2010-11-01

    Full Text Available Gerald S Lipshutz1, Elaine F Reed2, Phuong-Chi Pham3, Jeffrey M Miller4, Jennifer S Singer5, Gabriel M Danovitch6, Alan H Wilkinson6, Dean W Wallace7, Suzanne McGuire6, Phuong-Truc Pham8, Phuong-Thu Pham61Department of Surgery, Kidney and Pancreas Transplant Program, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Department of Pathology and Laboratory Medicine-Immunogenetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 3Department of Medicine, Nephrology Division, UCLA-Olive View Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 4Department of Medicine, Hematology Oncology Division, UCLA-Olive View Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 5Department of Surgery and Urology, Kidney and Pancreas Transplant Program, 6Department of Medicine, Nephrology Division, Kidney and Pancreas Transplant Program, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 7Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 8Department of Science, Penn State University, Worthington-Scranton, Dunmore, PA, USAAbstract: Over the past decade ABO incompatible transplantation has emerged as an important potential source for increasing living kidney transplantation in selected transplant centers. Early reports suggest that patients who have elevated serum anti-blood group antibody titers (anti-A/B before transplantation and a rebound antibody production after antibody removal may be at high immunological risk. With currently available immune modulation protocols and immunosuppressive therapy, excellent short- and long-term patient and graft survival rates have been achieved even in those with high anti-A/B antibody titers before plasmapheresis or immunoadsorption. Nonetheless, acute infection with an organism possessing surface markers analogous to blood group antigens such as carbohydrate structures on

  2. Comparing a Mobile Decision Support System Versus the Use of Printed Materials for the Implementation of an Evidence-Based Recommendation: Protocol for a Qualitative Evaluation.

    Science.gov (United States)

    Camacho, Jhon; Medina Ch, Ana María; Landis-Lewis, Zach; Douglas, Gerald; Boyce, Richard

    2018-04-13

    of clinical practice guidelines. Furthermore, we will provide qualitative evidence to aid decisions made by low- and middle-income countries' ministries of health about investments in these technologies. ©Jhon Camacho, Ana María Medina Ch, Zach Landis-Lewis, Gerald Douglas, Richard Boyce. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 13.04.2018.

  3. Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the Phase III OPTiM trial

    Directory of Open Access Journals (Sweden)

    Harrington KJ

    2016-11-01

    Full Text Available Kevin J Harrington,1 Robert HI Andtbacka,2 Frances Collichio,3 Gerald Downey,4 Lisa Chen,5 Zsolt Szabo,6 Howard L Kaufman7 1The Institute of Cancer Research/The Royal Marsden Hospital NIHR Biomedical Research Centre, London, UK; 2Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA; 3Division of Hematology and Oncology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 4Amgen Ltd, Cambridge, UK; 5Amgen Inc, Thousand Oaks, CA, USA; 6Amgen GmbH, Zug, Switzerland; 7Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA Objectives: Talimogene laherparepvec is the first oncolytic immunotherapy to receive approval in Europe, the USA and Australia. In the randomized, open-label Phase III OPTiM trial (NCT00769704, talimogene laherparepvec significantly improved durable response rate (DRR versus granulocyte-macrophage colony-stimulating factor (GM-CSF in 436 patients with unresectable stage IIIB–IVM1c melanoma. The median overall survival (OS was longer versus GM-CSF in patients with earlier-stage melanoma (IIIB–IVM1a. Here, we report a detailed subgroup analysis of the OPTiM study in patients with IIIB–IVM1a disease. Patients and methods: The patients were randomized (2:1 ratio to intralesional talimogene laherparepvec or subcutaneous GM-CSF and were evaluated for DRR, overall response rate (ORR, OS, safety, benefit–risk and numbers needed to treat. Descriptive statistics were used for subgroup comparisons. Results: Among 249 evaluated patients with stage IIIB–IVM1a melanoma, DRR was higher with talimogene laherparepvec compared with GM-CSF (25.2% versus 1.2%; P<0.0001. ORR was also higher in the talimogene laherparepvec arm (40.5% versus 2.3%; P<0.0001, and 27 patients in the talimogene laherparepvec arm had a complete response, compared with none in GM-CSF-treated patients. The incidence rates of exposure-adjusted adverse events (AE and serious AEs were similar with both treatments. Conclusion

  4. Ocular neovascularization in eyes with a central retinal artery occlusion or a branch retinal artery occlusion

    Directory of Open Access Journals (Sweden)

    Mason lll JO

    2015-06-01

    Full Text Available John O Mason III,1,2 Shyam A Patel,1 Richard M Feist,1,2 Michael A Albert Jr,1,2 Carrie Huisingh,1 Gerald McGwin Jr,1,3 Martin L Thomley1,2 1Department of Ophthalmology, University of Alabama School of Medicine, Birmingham, AL, USA; 2Retina Consultants of Alabama, Callahan Eye Foundation Hospital, Birmingham, AL, USA; 3Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA Purpose: To investigate the ocular neovascularization (ONV rate in eyes with a branch retinal artery occlusion (BRAO or a central retinal artery occlusion (CRAO, and to study factors that may influence the ONV rate secondary to CRAO.Methods: This was a retrospective case series of consecutive patients (286 total eyes: 83 CRAOs and 203 BRAOs who were diagnosed with a retinal artery occlusion from 1998 to 2013 at the Retina Consultants of Alabama and University of Alabama at Birmingham, Birmingham, AL, USA. Generalized estimating equations were used to evaluate the association between hypothesized risk factors and ONV development.Results: Twelve (14.5% of the 83 eyes with a CRAO developed ONV. Eleven of 12 eyes (91.7% had iris neovascularization, ten of 12 eyes (83.3% had neovascular glaucoma, and two of 12 eyes (16.7% had neovascularization of the optic disc. The average time for ONV development secondary to CRAO was 30.7 days, ranging from the date of presentation to 137 days. Only two (<1.0% of the 203 eyes with a BRAO developed iris neovascularization. Diabetes mellitus type 2 was a risk factor for ONV development following a CRAO with an adjusted odds ratio of 5.2 (95% confidence interval: 1.4–19.8 (P=0.02.Conclusion: ONV is an important complication of CRAO and is a less-frequent complication of BRAO. Patients with a CRAO, especially those with diabetes mellitus type 2, should be closely monitored for the first 6 months for ONV. Keywords: neovascularization, neovascular glaucoma, retinal artery occlusion, central

  5. Radiolabelled leucocyte scintigraphy versus conventional radiological imaging for the management of late, low-grade vascular prosthesis infections

    Energy Technology Data Exchange (ETDEWEB)

    Erba, P.A. [University of Pisa, and University Hospital of Pisa, Regional Center of Nuclear Medicine, Department of Translational Research and Advanced Technology in Medicine, Pisa (Italy); University of Pisa, Regional Center of Nuclear Medicine, Pisa (Italy); Leo, G. [ASL Lecce, U.O. Gestione Rapporti Convenzionali, U.O. Chirurgia Generale, Lecce, Pisa (Italy); University of Pisa, and University Hospital of Pisa, Division of Vascular Surgery, Department of Translational Research and Advanced Technology in Medicine, Pisa (Italy); Sollini, M. [Az. Osp. S.Maria Nuova - IRCCS Reggio Emilia, Nuclear Medicine Unit, Department of Oncology and Advanced Technology, Reggio Emilia (Italy); Tascini, C.; Menichetti, F. [University Hospital of Pisa, Division of Infectious Diseases, Pisa (Italy); Boni, R.; Lazzeri, E.; Mariani, G. [University of Pisa, and University Hospital of Pisa, Regional Center of Nuclear Medicine, Department of Translational Research and Advanced Technology in Medicine, Pisa (Italy); Berchiolli, R.N.; Ferrari, M. [University of Pisa, and University Hospital of Pisa, Division of Vascular Surgery, Department of Translational Research and Advanced Technology in Medicine, Pisa (Italy)

    2014-02-15

    In this study we evaluated the diagnostic performance of {sup 99m}Tc-HMPAO-leucocyte ({sup 99m}Tc-HMPAO-WBC) scintigraphy in a consecutive series of 55 patients (46 men and 9 women, mean age 71 ± 9 years, range 50 - 88 years) with a suspected late or a low-grade late vascular prosthesis infection (VPI), also comparing the diagnostic accuracy of WBC with that of other radiological imaging methods. All patients suspected of having VPI underwent clinical examination, blood tests, microbiology, US and CT, and were classified according to the Fitzgerald criteria. A final diagnosis of VPI was established in 47 of the 55 patients, with microbiological confirmation after surgical removal of the prosthesis in 36 of the 47. In the 11 patients with major contraindications to surgery, the final diagnosis was based on microbiology and clinical follow-up of at least 18 months. {sup 99m}Tc-HMPAO-WBC planar, SPECT and SPECT/CT imaging identified VPI in 43 of 47 patients (20 of these also showed infection at extra-prosthetic sites). In the remaining eight patients without VPI, different sites of infections were found. The use of SPECT/CT images led to a significant reduction in the number of false-positive findings in 37 % of patients (sensitivity and specificity 100 %, versus 85.1 % and 62.5 % for stand-alone SPECT). Sensitivity and specificity were 34 % and 75 % for US, 48.9 % and 83.3 % for CT, and 68.1 % and 62.5 % for the FitzGerald classification. Perioperative mortality was 5.5 %, mid-term mortality 12 %, and long-term mortality 27 %. Survival rates were similar in patients treated with surgery and antimicrobial therapy compared to patients treated with antimicrobial therapy alone (61 % versus 63 %, respectively), while infection eradication at 12 months was significantly higher following surgery (83.3 % versus 45.5 %). {sup 99m}Tc-HMPAO-WBC SPECT/CT is useful for detecting, localizing and defining the extent of graft infection in patients with late and low-grade late VPI

  6. Ernst Mach, George Sarton and the Empiry of Teaching Science Part I

    Science.gov (United States)

    Siemsen, Hayo

    2012-04-01

    George Sarton had a strong influence on modern history of science. The method he pursued throughout his life was the method he had discovered in Ernst Mach's Mechanics when he was a student in Ghent. Sarton was in fact throughout his life implementing a research program inspired by the epistemology of Mach. Sarton in turn inspired many others (James Conant, Thomas Kuhn, Gerald Holton, etc.). What were the origins of these ideas in Mach and what can this origin tell us about the history of science and science education nowadays? Which ideas proved to be successful and which ones need to be improved upon? The following article will elaborate the epistemological questions, which Darwin's "Origin" raised concerning human knowledge and scientific knowledge and which led Mach to adapt the concept of what is "empirical" in contrast to metaphysical a priori assumptions a second time after Galileo. On this basis Sarton proposed "genesis and development" as the major goal of Isis. Mach had elaborated this epistemology in La Connaissance et l'Erreur ( Knowledge and Error), which Sarton read in 1913 (Hiebert 1905/1976; de Mey 1984). Accordingly for Sarton, history becomes not only a subject of science, but a method of science education. Culture—and science as part of culture—is a result of a genetic process. History of science shapes and is shaped by science and science education in a reciprocal process. Its epistemology needs to be adapted to scientific facts and the philosophy of science. Sarton was well aware of the need to develop the history of science and the philosophy of science along the lines of this reciprocal process. It was a very fruitful basis, but a specific part of it, Sarton did not elaborate further, namely the psychology of science education. This proved to be a crucial missing element for all of science education in Sarton's succession, especially in the US. Looking again at the origins of the central questions in the thinking of Mach, which provided

  7. Radiolabelled leucocyte scintigraphy versus conventional radiological imaging for the management of late, low-grade vascular prosthesis infections

    International Nuclear Information System (INIS)

    Erba, P.A.; Leo, G.; Sollini, M.; Tascini, C.; Menichetti, F.; Boni, R.; Lazzeri, E.; Mariani, G.; Berchiolli, R.N.; Ferrari, M.

    2014-01-01

    In this study we evaluated the diagnostic performance of 99m Tc-HMPAO-leucocyte ( 99m Tc-HMPAO-WBC) scintigraphy in a consecutive series of 55 patients (46 men and 9 women, mean age 71 ± 9 years, range 50 - 88 years) with a suspected late or a low-grade late vascular prosthesis infection (VPI), also comparing the diagnostic accuracy of WBC with that of other radiological imaging methods. All patients suspected of having VPI underwent clinical examination, blood tests, microbiology, US and CT, and were classified according to the Fitzgerald criteria. A final diagnosis of VPI was established in 47 of the 55 patients, with microbiological confirmation after surgical removal of the prosthesis in 36 of the 47. In the 11 patients with major contraindications to surgery, the final diagnosis was based on microbiology and clinical follow-up of at least 18 months. 99m Tc-HMPAO-WBC planar, SPECT and SPECT/CT imaging identified VPI in 43 of 47 patients (20 of these also showed infection at extra-prosthetic sites). In the remaining eight patients without VPI, different sites of infections were found. The use of SPECT/CT images led to a significant reduction in the number of false-positive findings in 37 % of patients (sensitivity and specificity 100 %, versus 85.1 % and 62.5 % for stand-alone SPECT). Sensitivity and specificity were 34 % and 75 % for US, 48.9 % and 83.3 % for CT, and 68.1 % and 62.5 % for the FitzGerald classification. Perioperative mortality was 5.5 %, mid-term mortality 12 %, and long-term mortality 27 %. Survival rates were similar in patients treated with surgery and antimicrobial therapy compared to patients treated with antimicrobial therapy alone (61 % versus 63 %, respectively), while infection eradication at 12 months was significantly higher following surgery (83.3 % versus 45.5 %). 99m Tc-HMPAO-WBC SPECT/CT is useful for detecting, localizing and defining the extent of graft infection in patients with late and low-grade late VPI with inconclusive

  8. Post-mining water treatment. Nanofiltration of uranium-contaminated drainage. Experiments and modeling

    Energy Technology Data Exchange (ETDEWEB)

    Hoyer, Michael

    2017-07-01

    Nanofiltration of real uranium-contaminated mine drainage was successfully discussed in experiments and modeling. For the simulation a renowned model was adapted that is capable of describing multi-component solutions. Although the description of synthetic multi-component solutions with a limited number of components was performed before ([Garcia-Aleman2004], [Geraldes2006], [Bandini2003]) the results of this work show that the adapted model is capable of describing the very complex solution. The model developed here is based on: The Donnan-Steric Partitioning Pore Model incorporating Dielectric Exclusion - DSPM and DE ref. [Bowen1997], [Bandini2003], [Bowen2002], [Vezzani2002]. The steric, electric, and dielectric exclusion model - SEDE ref. [Szymczyk2005]. The developed modeling approach is capable of describing multi-component transport, and is based on the pore radius, membrane thickness, and volumetric membrane charge density as physically relevant membrane parameters instead of mere fitting parameters which allows conclusions concerning membrane modification or process design. The experiments involve typical commercially available membranes in combination with a water sample of industrial relevance in the mining sector. Furthermore, it has been shown experimentally that uranium speciation influences its retention. Hence, all experiments consider the speciation of uranium when assessing its charge and size. In the simulation 10 different ionic components have been taken into account. By freely fitting 4 parameters in parallel (pore radius, membrane thickness, membrane charge, relative permittivity of the oriented water layer at the pore wall) an excellent agreement between experiment and simulation was obtained. Moreover, the determined membrane thickness and pore radius is in close agreement with the values obtained by independent membrane characterization using pure water permeability and glucose retention. On the other hand, the fitted and the literature

  9. Reseñas de Libros

    Directory of Open Access Journals (Sweden)

    José Francisco Tinao Martín-Peña

    2008-12-01

    Full Text Available Chomsky, Noam, Poder y Terror. Reflexiones posteriores al 11/09/2001. Barcelona, RBA, 2003, 155 pp.Páginas 133-135José Francisco Tinao Martín-PeñaCobo Romero, Francisco, Conflicto rural y violencia política. Jaén, Universidad de Jaén-Universidad de Granada, 1998, 381 pp.Páginas 135-137José Luis Gutiérrez MolinaColacrai, Miryam (ed., Relaciones Internacionales. Viejos temas, nuevos debates. Rosario, Centro de Estudios en Relaciones Internacionales de Rosario, 2001, 203 pp.Páginas 137-141David Molina RabadánCuenca Toribio, José Manuel, Historia y actualidad. Clío en la posada. Madrid, Actas, 2002, 402 pp.Páginas 141-143Alejandro Román AntequeraHardt, Michael; Negri, Antonio, Imperio. Barcelona, Paidós, 2002, 432 pp.Páginas 143-145Jesús Fernández GarcíaHowson, Gerald, Armas para España. La historia no contada de la Guerra Civil Española. Barcelona, Península, 2000, 450 pp.Páginas 145-148Roberto Germán Fandiño PérezKaku, Michio, Visiones: cómo la ciencia revolucionará la materia, la vida y la mente en el siglo XXI. Madrid, Debate, 1998, 484 pp.Páginas 148-150Rafael Gómez SánchezLemus López, Encarnación, En Hamelin... la Transición española más allá de la frontera. Oviedo, Septem Ediciones, 2001, 158 pp.Páginas 150-153Julio Pérez SerranoSalazar Vergara, Gabriel, Labradores, peones y proletarios. Formación y crisis de la sociedad popular chilena del siglo XIX. Santiago de Chile, LOM Ediciones, 2000, 3ª ed., 334 pp.Páginas 153-155Leonardo Mazzei de GraziaSantacreu Soler, José Miguel, Peseta y política: Historia de la peseta, 1868-2001. Barcelona, Ariel Historia, 2002, 196 pp.Página 155Joaquín Piñeiro Blanca

  10. KONSTRUKSI PEMBERITAAN KONFLIK INDONESIA VS MALAYSIA DI SURAT KABAR (

    Directory of Open Access Journals (Sweden)

    Qoniah Nur Wijayani

    2012-03-01

    Full Text Available Confrontation between Indonesia and Malaysia frequently occurs. The conflicts between the two of nations then and now are always repeated and never go over. Since the Soekarno regime until Yudhoyono regime always comes up with several problems. On August 13, 2010, confrontation between Indonesia and Malaysia repeatedly happened. In the waters of Tanjung Berakit, Marine Police Malaysia (MPM have arrested Indonesian officials (Kementerian Kelautan dan Perikanan (KKP. Those reality has attracted a news media attentions for reporting. Jawa Pos and Kompas have performed Tanjung Berakit incident on the front pages for nearly a month. Both Jawa Pos and Kompas Kompas have published the reality in different perspective. Each of them constructs reality based on their views. Wanting to inves­tigate the construction of news media above, this study uses framing theory to analyze the method of framing models Zongdang Pan and Gerald Kosicki M. It operationalizes the four dimensions of structural text news: syntax, script, thematic, and rhetorical. This study found that Jawa Pos constructs reality reporting on the arrest of three KKP officer by Marine Police Malaysia as a conflict between two countries that attacks each other. Both are en­emies which opposites to each other. Malaysia has always been challenging Indonesia while Indonesia is not able to compensate. Disappointment refers to the Indonesian government. Jawa Pos thought that the settlement with take up arms can be done. Unlike The Jawa Pos case, Kompas constructs reporting on the arrest of three KKP officersis not a conflict be­tween the two countries. It can be seen from the attitude of both countrie thatis very contra­dictory. If Indonesia is really angry with Malaysia, in reserve Malaysia is keeps in silent as if nothing happened. Even Malaysia considers that Indonesia is their friend. Kompas does not want to deteriorate their relationship. Indonesia and Malaysia are the two allied coun

  11. SIX DECADES OF THE PULA NEUROPSYCHIATRIC MEETINGS--FROM NEUROPSYCHIATRY TO BORDERLANDS OF NEUROLOGY AND PSYCHIATRY BRAIN AND MIND.

    Science.gov (United States)

    Barac, Bosko; Demarin, Vida

    2015-12-01

    In 2010, the International Neuropsychiatric Pula Symposia, from 2005 Congresses (INPS/INPC), founded in 1961 by Zagreb and Graz University Neuropsychiatry Departments, celebrated their 50th anniversary of successful development. The co-author of the paper, Bosko Barac, witnessed their growth from 1966, collaborating in their organization from 1974 with the first Secretary General Gerald Grinschgl; elected for his successor after his unexpected death in 1985, he was leading the Kuratorium (Scientific Board) as Secretary General for 23 years, collaborating in this period with his Austrian partner and friend Helmut Lechner. In 2007, Barac handed over this responsible function to the co-author Vida Demarin. Starting when neuropsychiatry was a unique discipline, the INPC followed the processes of emancipation of neurology and psychiatry and their evolution to independent disciplines with new subspecialties. These respectable conferences greatly surpassed the significance of the two disciplines, neurology and psychiatry, granting collaboration of borderland medical and non-medical disciplines, connecting experts from the region, European countries and the world. Inaugurated in 'cold-war' times, in their first phase they enabled to make professional and human contacts between scientists from the two divided 'blocs' thanks to the 'non-aligned' position of the then Yugoslavia, fostering the ideas of mutual understanding and collaboration. On the other hand, the scientific development of the meetings took in the center of their study fields connecting the two disciplines, giving a quite unique quality to these meetings. For many years, the meetings cherished specific neurologic and psychiatric topics, at the same time planning increasing important topics of the 'borderland areas' in their programs. For the important achievements, they earned the title of the Pula School of Science and Humanism, promoting interdisciplinary scientific collaboration important for humanistic

  12. Causes of blindness in rural Myanmar (Burma: Mount Popa Taung-Kalat Blindness Prevention Project

    Directory of Open Access Journals (Sweden)

    Arie Y Nemet

    2009-07-01

    Full Text Available Arie Y Nemet1, Pinhas Nemet2, Geoff Cohn3, Gina Sutton, Gerald Sutton4, Richard Rawson41Department of Ophthalmology, Sydney Hospital and Sydney Eye Hospital, Sydney, Australia; 2Sackler School of Medicine, Tel-Aviv University, Israel; 3Departments of Ophthalmology, University of New South Wales, Sydney, Australia; 4Department of Ophthalmology, University of Sydney, AustraliaPurpose: This study is a review of the major causes of visual impairment (VI and severe visual impairment/blindness (SVI/BL in Mount Popa Taung-Kalat, a rural region in Myanmar (Burma.Methods: A review of our clinical records of consecutive patients attending clinics was conducted. Participants of all ages (n = 650 of the population of Mount Popa Taung-Kalat and villages in its vicinity underwent ophthalmic interview and a detailed dilated ocular evaluation by trained Australian ophthalmologists and ophthalmic nurses. This evaluation included anterior segment examination with a slit lamp, intraocular pressure recording, and direct or indirect ophthalmoscopy. VI and SVI/BL were defined by the World Health Organization (WHO criteria. Results: Six hundred fifty subjects were screened, with a mean age of 49.0 ± 20.6 years (range, 1–99. One hundred five patients (16.2% were children (ages 1–18. Five hundred thirty-one eyes of the total 1,300 eyes (39.5% had VI/SVI/BL, and 40 eyes of the children (38.1% (average age 15.3 ± 13.3 had VI/SVI/BL. The leading causes of VI/SVI/BL were cataract with 288 cases (54.2%, glaucoma with 84 cases (15.8%, and corneal pathology with 78 cases (14.7%. Of all the VI/SVI/BL cases, 8.4% were preventable, 81.9% were treatable, and total of 90.5% were avoidable.Conclusions: In the current study, cataracts were the major cause of blindness and visual impairment, and most of the ophthalmic pathology causing blindness is avoidable. These results highlight the lack of basic ophthalmologist eye care and optician resources in rural regions in Myanmar

  13. Cycloid psychoses in the psychosis spectrum: evidence for biochemical differences with schizophrenia

    Directory of Open Access Journals (Sweden)

    van de Kerkhof NW

    2016-08-01

    Full Text Available Nora WA van de Kerkhof,1,2 Durk Fekkes,2,3 Frank MMA van der Heijden,1 Witte JG Hoogendijk,2 Gerald Stöber,4 Jos IM Egger,1,5,6 Willem MA Verhoeven1,2 1Vincent van Gogh Institute for Psychiatry, Centre of Excellence for Neuropsychiatry, Venray, 2Department of Psychiatry, 3Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands; 4Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany; 5Behavioural Science Institute, 6Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands Abstract: Cycloid psychoses (CP differ from schizophrenia regarding symptom profile, course, and prognosis and over many decades they were thought to be a separate entity within the psychosis spectrum. As to schizophrenia, research into the pathophysiology has focused on dopamine, brain-derived neurotrophic factor, and glutamate signaling in which, concerning the latter, the N-methyl-d-aspartate receptor plays a crucial role. The present study aims to determine whether CP can biochemically be delineated from schizophrenia. Eighty patients referred for psychotic disorders were assessed with the Comprehensive Assessment of Symptoms and History, and (both at inclusion and after 6 weeks of antipsychotic treatment with the Positive and Negative Syndrome Scale and Clinical Global Impression. From 58 completers, 33 patients were diagnosed with schizophrenia and ten with CP according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and Leonhard criteria, respectively. Fifteen patients were diagnosed with other disorders within the psychosis spectrum. At both time points, blood levels of the dopamine metabolite homovanillic acid, brain-derived neurotrophic factor, and amino acids related to glutamate neurotransmission were measured and compared with a matched control sample. Patients with CP showed a significantly

  14. Efficacy and safety of anakinra for the treatment of rheumatoid arthritis: an update of the Oregon Drug  Effectiveness Review Project

    Directory of Open Access Journals (Sweden)

    Kylie Thaler

    2009-11-01

    Full Text Available Kylie Thaler1, Divya V Chandiramani2, Richard A Hansen2, Gerald Gartlehner11Department for Evidence-based Medicine and Clinical Epidemiology, Danube University Krems, Krems, Austria; 2UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAObjective: To systematically review the general and comparative efficacy and safety of anakinra for rheumatoid arthritis.Methods: We searched MEDLINE®, Embase, The Cochrane Library, and the International Pharmaceutical Abstracts from 1980 to April 2009. We manually searched reference lists of pertinent review articles and explored the Center for Drug Evaluation and Research database. For efficacy we included randomized controlled trials (RCTs comparing anakinra with placebo or other biologics. For safety both experimental and observational studies were eligible. Two persons independently reviewed abstracts and full text articles and extracted relevant data.Results: We included data from 3 RCTs comparing anakinra with placebo for rheumatoid arthritis (RA. The pooled relative risk (RR of an ACR50 (American College of Rheumatology response for anakinra compared with placebo is 2.28 (95% CI 1.41 to 3.67. Adjusted indirect comparisons of ACR50 response rates of anakinra and anti-TNF agents showed a RR of 0.67 (95% CI 0.38 to 1.17 favoring the anti-TNF drugs. This result did not reach statistical significance. For safety, we included 9 experimental and observational studies of 24 weeks to 3 years duration. Up to 30% of patients withdrew from the studies due to adverse events. 67.2% (95% CI 38.7 to 95.7 of patients experienced an injection site reaction.Conclusions: Anakinra is an effective drug for treating RA. Indirect comparisons with adalimumab, etanercept and infliximab, however, showed a trend towards greater efficacy for the anti-TNF drugs. Anakinra also seems to be associated with comparably high rates of injection site reactions. These results should be taken into

  15. Educación para la ciudadanía global : significados y espacios para un cosmopolitismo transformador

    Directory of Open Access Journals (Sweden)

    Alejandra Boni Aristizábal

    2011-01-01

    Full Text Available El presente artículo tiene como objetivo profundizar en los significados de la ciudadanía global con el fin de caracterizar las prácticas pedagógicas de lo que se conoce como educación para la ciudadanía global. Tras una breve análisis de las distintas etapas por las que ha pasado la educación para el desarrollo, desde el planteamiento asistencialista de los años 50 hasta la educación para la ciudadanía global, nos detenemos en diferentes perspectivas del cosmopolitismo: la visión desde la ética, fundamentalmente a través de la obra de Martha Nussbaum que nos habla de las habilidades cosmopolitas, desde la política, que contiene propuestas de democracia como las de David Held y perspectivas más críticas como las de Boaventura de Sousa Santos, y la perspectiva sociológica que nos permite identificar los procesos de comunicación intercultural donde se produce la mirada cosmopolita, según palabras de Ulrick Beck o Gerard Delanty. Tras ello, concluiremos con una discusión sobre cómo potenciar espacios de educación para el desarrollo desde donde contribuir a la formación de ciudadanos globales.In this paper we want to address the different meanings of global citizenship in order to characterize the pedagogical practices of what has been named as education for global citizenship. After a short analysis of the different stages of development education, from a patronizing approach of the 50s to the actual education for global citizenship, we will discussing meanings and perspectives of cosmopolitism: an ethical perspective, mainly through Martha Nussbaum writings who speaks of cosmopolitan abilities, a political perspective, with Held’s visionon global democracy or Sousa Santos radical view of western democracy, and a sociological perspective that allows as to identify process of intercultural communication where the cosmopolitan outlook could take place, following Ulrick Beck and Gerald Delanty proposals. We conclude this

  16. The evolving role of alemtuzumab (Campath-1H in renal transplantation

    Directory of Open Access Journals (Sweden)

    Phuong-Thu T Pham

    2008-12-01

    Full Text Available Phuong-Thu T Pham1, Gerald S Lipshutz2, Phuong-Truc T Pham3, Joseph Kawahji1, Jennifer S Singer4, Phuong-Chi T Pham51Division of Nephrology, Department of Medicine, Kidney and Pancreas Transplant Program, University of California at Los Angeles, David Geffen School of Medicine, Los Angeles, California; 2Kidney and Pancreas Transplant Program, Department of Surgery and Urology, University of California at Los Angeles, David Geffen School of Medicine, Los Angeles, California; 3Department of Science, Penn State University, Worthington-Scranton, Dunmore, Pennsylvania; 4Renal Transplantation and Pediatric Urology, Department of Urology, University of California at Los Angeles, David Geffen School of Medicine, Los Angeles, California; 5Division of Nephrology, Department of Medicine, University of California at Los Angeles, David Geffen School of Medicine, Los Angeles, and Olive-View-UCLA Medical Center, Sylmar, California, USAAbstract: The introduction of new immunosuppressive agents into clinical transplantation in the 1990s has resulted in excellent short-term graft survival. Nonetheless, extended long-term graft outcomes have not been achieved due in part to the nephrotoxic effects of calcineurin inhibitors (CNIs and the adverse effects of steroid on cardiovascular disease risk factors. Induction therapy with lymphocyte depleting antibodies has originally been introduced into renal transplantation to provide intense immunosuppression in the early post-transplant period to prevent allograft rejection. Over the past half decade, induction therapy with both non-lymphocyte depleting (basiliximab and daclizumab and lymphocyte-depleting antibodies (antithymocyte antibodies, OKT3, alemtuzumab has increasingly been utilized in steroid or CNI sparing protocols in the early postoperative period. Alemtuzumab is a humanized monoclonal antibody targeted against CD52 on the surface of circulatory mononuclear cells. The ability of alemtuzumab (Campath-1H to

  17. Microencapsulation as a novel delivery method for the potential antidiabetic drug, Probucol

    Directory of Open Access Journals (Sweden)

    Mooranian A

    2014-09-01

    Full Text Available Armin Mooranian,1 Rebecca Negrulj,1 Nigel Chen-Tan,2 Hesham S Al-Sallami,3 Zhongxiang Fang,4 TK Mukkur,5 Momir Mikov,6,7 Svetlana Golocorbin-Kon,6,7 Marc Fakhoury,8 Gerald F Watts,9 Vance Matthews,10 Frank Arfuso,5 Hani Al-Salami1 1Biotechnology and Drug Development Research Laboratory School of Pharmacy, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, Perth, Western Australia, Australia; 2Faculty of Science and Engineering, Curtin University, Perth, Western Australia, Australia; 3School of Pharmacy, University of Otago, Dunedin, New Zealand; 4School of Public Health, Curtin University, Perth, Western Australia, Australia; 5Curtin Health Innovation Research Institute, Biosciences Research Precinct, School of Biomedical Science, Curtin University, Perth, Western Australia, Australia; 6Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Serbia; 7Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Serbia; 8Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada; 9School of Medicine and Pharmacology, Royal Perth Hospital, University of Western Australia; 10Laboratory for Metabolic Dysfunction, UWA Centre for Medical Research, Harry Perkins Institute of Medical Research, Perth, Western Australia, Australia Introduction: In previous studies, we successfully designed complex multicompartmental microcapsules as a platform for the oral targeted delivery of lipophilic drugs in type 2 diabetes (T2D. Probucol (PB is an antihyperlipidemic and antioxidant drug with the potential to show benefits in T2D. We aimed to create a novel microencapsulated formulation of PB and to examine the shape, size, and chemical, thermal, and rheological properties of these microcapsules in vitro. Method: Microencapsulation was carried out using the Büchi-based microencapsulating system developed in our laboratory. Using the polymer, sodium

  18. Atoms for the Future. Conference proceedings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-11-15

    Under the management of Silvain Ikazaki who organised Atoms for the Future 2011, the conferences have taken place in Paris, at ENSTA Paris Tech engineering school. It was Isabelle Tanchou, ENSTA, Deen of Education and Research who opened the two days of conferences of Atoms for the Future 2011 on the fuel cycle in front of more than a hundred young professionals coming from all Europe, Sri Lanka, Japan.. Then Laurent Stricker, chairman of WANO detailed the consequences of the Fukushima accident on nuclear industry and safety and which role the WANO was playing in this current situation. Jean-Pierre Gros, Areva executive vice-president of recycling business unit and CEO of MELOX facility, explained the reprocessing and recycling of used fuels through La Hague and MELOX operation. He specified that 96% of a used fuel is recyclable although most of used fuel is today stored in pools. This presentation was completed by the operator point of view of the nuclear fuel cycle given by Michel Pays, EDF director of strategy and risks at the nuclear fuel department. Georges Capus, Areva vice president marketing Frond End, explained the strategic, economic and political considerations of this activity. The afternoon conferences continued with the intervention of Bernard Boullis, CEA director nuclear fuel cycle back-end programs. He gave us an overview of the future nuclear fuel cycles detailing fast reactors examples such as ASTRID, ALLEGRO.. Radioactive materials need a safe, secure and efficient transport: it was the theme Michel Hartenstein, World Nuclear Transport Institute director. He illustrated his presentation with a very impressive video of the different qualification tests a canister has to undergo. The first day of lectures was closed by Gerald Ouzounian, ANDRA director of International Division. He exposed the radioactive waste management in France, describing the classification of those wastes depending on the radioactivity level, the existing sites, the current

  19. Atoms for the Future. Conference proceedings

    International Nuclear Information System (INIS)

    2011-11-01

    Under the management of Silvain Ikazaki who organised Atoms for the Future 2011, the conferences have taken place in Paris, at ENSTA Paris Tech engineering school. It was Isabelle Tanchou, ENSTA, Deen of Education and Research who opened the two days of conferences of Atoms for the Future 2011 on the fuel cycle in front of more than a hundred young professionals coming from all Europe, Sri Lanka, Japan.. Then Laurent Stricker, chairman of WANO detailed the consequences of the Fukushima accident on nuclear industry and safety and which role the WANO was playing in this current situation. Jean-Pierre Gros, Areva executive vice-president of recycling business unit and CEO of MELOX facility, explained the reprocessing and recycling of used fuels through La Hague and MELOX operation. He specified that 96% of a used fuel is recyclable although most of used fuel is today stored in pools. This presentation was completed by the operator point of view of the nuclear fuel cycle given by Michel Pays, EDF director of strategy and risks at the nuclear fuel department. Georges Capus, Areva vice president marketing Frond End, explained the strategic, economic and political considerations of this activity. The afternoon conferences continued with the intervention of Bernard Boullis, CEA director nuclear fuel cycle back-end programs. He gave us an overview of the future nuclear fuel cycles detailing fast reactors examples such as ASTRID, ALLEGRO.. Radioactive materials need a safe, secure and efficient transport: it was the theme Michel Hartenstein, World Nuclear Transport Institute director. He illustrated his presentation with a very impressive video of the different qualification tests a canister has to undergo. The first day of lectures was closed by Gerald Ouzounian, ANDRA director of International Division. He exposed the radioactive waste management in France, describing the classification of those wastes depending on the radioactivity level, the existing sites, the current

  20. Role of Spiral and Multislice Computed Tomography in the evaluation of traumatic and spontaneous oesophageal perforation. Our experience; Ruolo della Tomografia Computerizzata Spirale e Multistrato nello studio delle lesioni traumatiche e spontanee dell'esofago: nostra esperienza

    Energy Technology Data Exchange (ETDEWEB)

    De Lutio di Castelguidone, Elisabetta; Pinto, Antonio; Merola, Stefanella; Stavolo, Ciro; Romano, Luigia [Azienda Ospedaliera di Rilievo Nazionale A. Cardarelli, Napoli (Italy). Dipartimento di Diagnostica per Immagini

    2005-03-01

    oesophageal perforation, CT showed the presence of a intramural haematoma in one case, oesophageal fluid distension with gas and a small peri-oesophageal fluid effusion (Mallory-Weiss syndrome) in another, and oesophageal rapture (Boerhaave syndrome) in the last case. Conclusions: Our experience shows that in patients with suspected traumatic and spontaneous oesophageal perforation, standard cervical and chest radiography may suggest a suspected oesophageal perforation in only a small proportion of cases, whereas oral contrast oesophagography has a higher sensitivity. Through the careful analysis of suggestive and specific signs of oesophageal perforation, a correct CT examination enables an accurate and timely diagnosis which significantly affects prognosis and provides valuable indications for treatment. [Italian] Scopo: Presentare la nostra esperienza relativa al ruolo della TC nello studio delle perforazioni traumatiche e spontanee dell'esofago. Materiale e metodi: Da marzo 2001 a maggio 2003 sono giunti alla nostra osservazione 12 pazienti (7 di sesso maschile, 5 di sesso femminile, di eta' compresa tra 25 e 66 anni, eta' media 43,5) con sospetta lesione esofagea da incidente stradale (in 4 casi), ferita d'arma bianca (un caso), post-intubazione (2 casi), da indigestione di corpo estraneo (2 casi) e di tipo spontaneo (3 casi). Cinque pazienti praticavano l'esame standard del torace e della regione cervicale. In 2 pazienti con sospetta indigestione di corpo estraneo veniva somministrato gastrografin per os. In tutti i 12 casi veniva eseguito l'esame TC del collo-torace-addome senza e con mdc ev e con mdc idrosolubile per os in 4 casi. Risultati: Nei 5 pazienti con trauma cervico-toracico-addominale l'indagine TC evidenziava oltre a lesioni traumatiche pleuro-parenchimali (pneumotorace, versamento pleurico ed enfisema sottocutaneo) anche reperti suggestivi di perforazione esofagea: aria mediastinica in sede periesofagea (5 casi), fluido

  1. Editorial

    Directory of Open Access Journals (Sweden)

    Márcio Matias

    2012-01-01

    Full Text Available Prezados Leitores, Nesta edição especial, a Encontros Bibli publica os trabalhos apresentados no 3º Simpósio Brasileiro de Comunicação Científica (SBCC, realizado na Universidade Federal de Santa Catarina (UFSC, em Florianópolis, nos dias 5 e 6 de junho de 2012. É uma grande satisfação estabelecer parceria com este evento, pois o SBCC é um importante fórum que agrupa especialistas, promove discussões e o compartilhamento de informações relacionadas à área de comunicação científica. Nesta edição de 2012, o evento concentrou-senos temas de acesso aberto, acesso livre e preservação digital, com foco em Perspectivas em Acesso Aberto – Cenários para 2020. O trabalho que abre esta edição fundamentou a palestra da professora pesquisadora Elena Maceviciute da Universidade de Boras - Suécia, e também da Universidade Vilnius - Lituânia, e destaca diversos questionamentos e alternativas para a preservação digital. Em seguida, temoso resultado de uma pesquisa sobre a produção científica brasileira relacionada ao tema principal do evento:Mapeamento da produção científica brasileira sobre Acesso Aberto: 2001 A 2011, elaborado por Fábio Mascarenhas Silva, Natanael Vitor Sobral, Guilherme Alves Santana eTatyane Lucia Cruz. Na sequência, são apresentados mais quatro trabalhos focados especificamente em Acesso Aberto: Serviços de difusão de políticas para o acesso aberto: Sherpa/Juliet, Melibea e ROARMAP, de Michelli Costa, Bianca Amaro e Tainá Assis; Acesso aberto à informação científica e direito autoral: ações e contradições, de Maria Naires Alves de Souza, Denyse Maria Borges Paes, Rafael Gomes Fernandes, Francisco Welton Silva Rios; A influência do Open Access nas comunidades Acadêmicas da Área de Biblioteconomia no Nordeste do Brasil, deVirgínia Bárbara Aguiar Alves; e Definição de uma política de acesso aberto para a Universidade Federal da Bahia. Susane Santos Barros, Flávia Goulart Mota

  2. Genomes to Life Project Quartely Report October 2004.

    Energy Technology Data Exchange (ETDEWEB)

    Heffelfinger, Grant S.; Martino, Anthony; Rintoul, Mark Daniel; Geist, Al; Gorin, Andrey; Xu, Ying; Palenik, Brian

    2005-02-01

    .genomes-to-life.org Acknowledgment We want to gratefully acknowledge the contributions of the GTL Project Team as follows: Grant S. Heffelfinger1*, Anthony Martino2, Andrey Gorin3, Ying Xu10,3, Mark D. Rintoul1, Al Geist3, Matthew Ennis1, Hashimi Al-Hashimi8, Nikita Arnold3, Andrei Borziak3, Bianca Brahamsha6, Andrea Belgrano12, Praveen Chandramohan3, Xin Chen9, Pan Chongle3, Paul Crozier1, PguongAn Dam10, George S. Davidson1, Robert Day3, Jean Loup Faulon2, Damian Gessler12, Arlene Gonzalez2, David Haaland1, William Hart1, Victor Havin3, Tao Jiang9, Howland Jones1, David Jung3, Ramya Krishnamurthy3, Yooli Light2, Shawn Martin1, Rajesh Munavalli3, Vijaya Natarajan3, Victor Olman10, Frank Olken4, Brian Palenik6, Byung Park3, Steven Plimpton1, Diana Roe2, Nagiza Samatova3, Arie Shoshani4, Michael Sinclair1, Alex Slepoy1, Shawn Stevens8, Chris Stork1, Charlie Strauss5, Zhengchang Su10, Edward Thomas1, Jerilyn A. Timlin1, Xiufeng Wan11, HongWei Wu10, Dong Xu11, Gong-Xin Yu3, Grover Yip8, Zhaoduo Zhang2, Erik Zuiderweg8 *Author to whom correspondence should be addressed (gsheffe%40sandia.gov) 1. Sandia National Laboratories, Albuquerque, NM 2. Sandia National Laboratories, Livermore, CA 3. Oak Ridge National Laboratory, Oak Ridge, TN 4. Lawrence Berkeley National Laboratory, Berkeley, CA 5. Los Alamos National Laboratory, Los Alamos, NM 6. University of California, San Diego 7. University of Illinois, Urbana/Champaign 8. University of Michigan, Ann Arbor 9. University of California, Riverside 10. University of Georgia, Athens 11. University of Missouri, Columbia 12. National Center for Genome Resources, Santa Fe, NM Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  3. Social Media Impact of the Food and Drug Administration's Drug Safety Communication Messaging About Zolpidem: Mixed-Methods Analysis.

    Science.gov (United States)

    Sinha, Michael S; Freifeld, Clark C; Brownstein, John S; Donneyong, Macarius M; Rausch, Paula; Lappin, Brian M; Zhou, Esther H; Dal Pan, Gerald J; Pawar, Ajinkya M; Hwang, Thomas J; Avorn, Jerry; Kesselheim, Aaron S

    2018-01-05

    first DSC. ITS analyses demonstrated variability but pointed to an increase in interest around the first DSC. Chow tests were significant (PSocial media offers challenges and opportunities for dissemination of the DSC messages. The FDA could consider strategies for more actively disseminating DSC safety information through social media platforms, particularly when announcements require updating. The FDA may also benefit from directly contributing content to websites like Wikipedia that are frequently accessed for drug-related information. ©Michael S Sinha, Clark C Freifeld, John S Brownstein, Macarius M Donneyong, Paula Rausch, Brian M Lappin, Esther H Zhou, Gerald J Dal Pan, Ajinkya M Pawar, Thomas J Hwang, Jerry Avorn, Aaron S Kesselheim. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 05.01.2018.

  4. European Society for Swallowing Disorders – European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome

    Directory of Open Access Journals (Sweden)

    Baijens LW

    2016-10-01

    Full Text Available Laura WJ Baijens,1 Pere Clavé,2,3 Patrick Cras,4 Olle Ekberg,5 Alexandre Forster,6 Gerald F Kolb,7 Jean-Claude Leners,8 Stefano Masiero,9 Jesús Mateos-Nozal,10 Omar Ortega,2,3 David G Smithard,11 Renée Speyer,12 Margaret Walshe13 1Department of Otorhinolaryngology – Head and Neck Surgery, Maastricht University Medical Center, Maastricht, the Netherlands; 2Gastrointestinal Physiology Laboratory, Department of Surgery, Hospital of Mataró, Autonomous University of Barcelona, Mataró, 3CIBERehd, Instituto de Salud Carlos III, Barcelona, Spain; 4Department of Neurology, Antwerp University Hospital, University of Antwerp, Born Bunge Institute, Edegem, Belgium; 5Department of Translational Medicine, Division of Medical Radiology, Skåne University Hospital, Malmö, Sweden; 6Clinique Bois-Bougy, Nyon, Switzerland; 7Department of Geriatrics and Physical Medicine, Bonifatius Hospital, Lingen, Germany; 8Long Term Care and Hospice, Ettelbruck, Luxembourg; 9Rehabilitation Unit, Department of Neuroscience, University of Padua, Padova, Italy; 10Department of Geriatric Medicine, Hospital Ramón y Cajal, Madrid, Spain; 11Clinical Gerontology, Princess Royal University Hospital, King’s College Hospital Foundation Trust, London, UK; 12College of Healthcare Sciences, James Cook University, Townsville, QLD, Australia; 13Department of Clinical Speech and Language Studies, Trinity College Dublin, Dublin, Ireland Abstract: This position document has been developed by the Dysphagia Working Group, a committee of members from the European Society for Swallowing Disorders and the European Union Geriatric Medicine Society, and invited experts. It consists of 12 sections that cover all aspects of clinical management of oropharyngeal dysphagia (OD related to geriatric medicine and discusses prevalence, quality of life, and legal and ethical issues, as well as health economics and social burden. OD constitutes impaired or uncomfortable transit of food or liquids

  5. The SunCloud project: An initiative for a development of a worldwide sunshine duration and cloudiness observations dataset

    Science.gov (United States)

    Sanchez-Lorenzo, A.

    2010-09-01

    (martin.wild@env.ethz.ch) E. Pallé, Institute of Astrophysics of the Canary Islands, Spain (epalle@iac.es) J. Calbó, Group of Environmental Physics, University of Girona, Spain (josep.calbo@udg.edu) M. Brunetti, Institute of Atmospheric Sciences and Climate, Italian National Research Council, Italy (m.brunetti@isac.cnr.it) G. Stanhill, Department of Environmental Physics and Irrigation, The Volcani Center, Israel (gerald@volcani.agri.gov.il) R. Brázdil, Institute of Geography, Masaryk University, Czech Republic (brazdil@sci.muni.cz) M. Barriendos, Department of Modern History, University of Barcelona, Spain (mbarriendos@ub.edu) C. Deser, National Center for Atmospheric Research, USA (cdeser@ucar.edu) P. Pereira, Department of Environmental Protection, Vilnius Gediminas Technical University, Lithuania (pereiraub@gmail.com) C. Azorin-Molina, The CEAM Foundation (Fundación Centro de Estudios Ambientales del Mediterráneo), Spain (cazorin@ceam.es) Q. You, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing, China (yqingl@126.com)

  6. PLANNING IN ARTIFICIAL INTELLIGENCE AND ROBOTICS (PAIR

    Directory of Open Access Journals (Sweden)

    Editorial, Foreword

    2016-11-01

    Full Text Available September 18th, 2016Deggendorf, Germanyhttp://robotics.fel.cvut.cz/pair16/Organized by: Artificial Intelligence Center Department of Computer Science Faculty of Electrical Engineering Czech Technical University in PragueTechnicka 2, Prague 6, 166 27, Czech RepublicGuest editors:Jan Faigl (Artificial Intelligence Center, Department of Computer Science, Faculty of Electrical Engineering, Czech Technical University in PragueJiří Vokřínek (Artificial Intelligence Center, Department of Computer Science, Faculty of Electrical Engineering, Czech Technical University in PragueScientific comittee:D. Belter (Poznań University of Technology, PolandW. Dorner (Technische Hochschule Deggendorf, GermanyJ. Faigl (Czech Technical University in PragueT. Krajník (University of Lincoln, United KingdomA. Komenda (Czech Technical University in PragueG. Kupris (Technische Hochschule Deggendorf, GermanyM. Rollo (Czech Technical University in PragueM. Saska (Czech Technical University in PragueJ. Vokřínek (Czech Technical University in PragueV. Vonásek (Czech Technical University in PragueK. Walas (Poznań University of Technology, Poland Foreword:The third year of the student conference on “Planning in Artificial Intelligence and Robotics” (PAIR continues in joining young researchers and students interested in robotics and artificial intelligence. In 2016, we follow the schema of the last year as a joint event with the RoboTour competition in Deggendorf, Germany. Thanks to the great collaboration with Gerald Kupris and Wolfgang Donner from Technische Hochschule Deggendorf and support from Czech Technical University under project No. SVK 26/16/F3 and Bayerisches Staatsministerium der Finanzen, für Landesentwicklung und Heimat, we have been able to provide accommodations and travel support to participants and an invited speaker. Fourteen papers have accepted and listed in the conference program. The papers have been authored by students from Central Europe

  7. Eye Care Quality and Accessibility Improvement in the Community (EQUALITY: impact of an eye health education program on patient knowledge about glaucoma and attitudes about eye care

    Directory of Open Access Journals (Sweden)

    Rhodes LA

    2016-05-01

    Full Text Available Lindsay A Rhodes,1 Carrie E Huisingh,1 Gerald McGwin Jr,1,2 Stephen T Mennemeyer,3 Mary Bregantini,4 Nita Patel,4 Jinan Saaddine,5 John E Crews,5 Christopher A Girkin,1 Cynthia Owsley11Department of Ophthalmology, School of Medicine, 2Department of Epidemiology, 3Department of Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, 4Prevent Blindness, Chicago, IL, USA; 5Vision Health Initiative, Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA, USAPurpose: To assess the impact of the education program of the Eye Care Quality and Accessibility Improvement in the Community (EQUALITY telemedicine program on at-risk patients’ knowledge about glaucoma and attitudes about eye care as well as to assess patient satisfaction with EQUALITY.Patients and methods: New or existing patients presenting for a comprehensive eye exam (CEE at one of two retail-based primary eye clinics were enrolled based on ≥1 of the following at-risk criteria for glaucoma: African Americans ≥40 years of age, Whites ≥50 years of age, diabetes, family history of glaucoma, and/or preexisting diagnosis of glaucoma. A total of 651 patients were enrolled. A questionnaire was administered prior to the patients’ CEE and prior to the patients receiving any of the evidence-based eye health education program; a follow-up questionnaire was administered 2–4 weeks later by phone. Baseline and follow-up patient responses regarding knowledge about glaucoma and attitudes about eye care were compared using McNemar’s test. Logistic regression models were used to assess the association of patient-level characteristics with improvement in knowledge and attitudes. Overall patient satisfaction was summarized.Results: At follow-up, all patient responses in the knowledge and attitude domains significantly improved from baseline (P≤0.01 for all questions. Those who were unemployed (odds

  8. 17th Workshop on MHD Stability Control: addressing the disruption challenge for ITER

    Science.gov (United States)

    Buttery, Richard

    2013-08-01

    of the art in 3D modeling, and innovative means of control through application of electromagnetic torques, use of electron cyclotron current drive and even the idea of electrostatic current drive. This concluded with a second panel discussion on the disruption avoidance strategy in ITER, which commented on the important role played by energetic particles in stability, ideas of active stability sensing and ways to progress 3D reconstruction. In this special section of Plasma Physics and Controlled Fusion , we present several of the invited and contributed papers from the 2012 workshop, which have been subject to the normal refereeing procedures of the journal. These give a sense of the exceptional quality of the presentations at this workshop, which may be found at: http://fusion.gat.com/conferences/mhd12/. The Program Committee deeply appreciates the participation and support our community continues to show in this workshop, which provides an unparalleled opportunity for in-depth discussion of MHD issues. We would also like to thank our hosts Columbia University, and in particular Professor Gerald Navratil, for outstanding support and facilities in the face of Hurricane Sandy's adversity. The meeting thanked outgoing Program Chair, Dr Richard Buttery from General Atomics, and welcomed next year's Program Chair, Professor David Maurer from Auburn University. The next meeting will be held in Santa Fe 18-20 November 2013.

  9. Indirect treatment comparison of bevacizumab + interferon-α-2a vs tyrosine kinase inhibitors in first-line metastatic renal cell carcinoma therapy

    Directory of Open Access Journals (Sweden)

    Gerald HJ Mickisch

    2011-01-01

    Full Text Available Gerald HJ Mickisch1, Björn Schwander2, Bernard Escudier3, Joaquim Bellmunt4, José P Maroto5, Camillo Porta6, Stefan Walzer7, Uwe Siebert8,91Department of Urology, Center of Operative Urology Bremen, Bremen, Germany; 2Department of Outcomes Research, AiM GmbH Assessment-in-Medicine, Lörrach, Germany; 3Immunotherapy Unit, Institut Gustave Roussy, Villejuif, France; 4Department of Medical Oncology, University Hospital del Mar UPF, Barcelona, Spain; 5Department of Medical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 6Department of Medical Oncology, IRCCS San Matteo University Hospital Foundation, Pavia, Italy; 7Global Health Economics, F Hoffmann-La Roche Pharmaceuticals AG, Basel, Switzerland; 8Department of Public Health, Medical Decision Making and Health Technology Assessment, UMIT - University for Health Sciences, Medical Informatics and Technology, Hall i.T., Austria; 9Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USABackground: The vascular endothelial growth factor inhibitor bevacizumab (BEV given in combination with interferon-α-2a (IFN, and the tyrosine kinase inhibitors (TKIs sunitinib (SUN and pazopanib (PAZ, have all shown significant increase in progression-free survival (PFS in first-line metastatic renal-cell carcinoma (mRCC therapy. These targeted therapies are currently competing to be primary choice; hence, in the absence of direct head-to-head comparison, there is a need for valid indirect comparison assessment.Methods: Standard indirect comparison methods were applied to independent review PFS data of the pivotal Phase III trials, to determine indirect treatment comparison hazard-ratios (HR with 95% confidence intervals (95% CI. As BEV+IFN and SUN have been compared to IFN, indirect comparison was enabled by the common IFN comparator arms. As PAZ was compared to placebo (PLA, a connector trial (IFN vs PLA was required for the indirect comparison to BEV

  10. EAARL coastal topography-western Florida, post-Hurricane Charley, 2004: seamless (bare earth and submerged.

    Science.gov (United States)

    Nayegandhi, Amar; Bonisteel, Jamie M.; Wright, C. Wayne; Sallenger, A.H.; Brock, John C.; Yates, Xan

    2010-01-01

    processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of lidar data in an interactive or batch mode. Modules for presurvey flight-line definition, flight-path plotting, lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant return within each waveform. ALPS is used routinely to create maps that represent submerged or sub-aerial topography. Specialized filtering algorithms have been implemented to determine the 'bare earth' under vegetation. For more information about similar projects, please visit the Decision Support for Coastal Science and Management website. Selected References Brock, J.C., Wright, C.W., Sallenger, A.H., Krabill, W.B., and Swift, R.N., 2002, Basis and methods of NASA airborne topographic mapper Lidar surveys for coastal studies: Journal of Coastal Research, v. 18, no. 1, p. 1-13. Crane, Michael, Clayton, Tonya, Raabe, Ellen, Stoker, Jason, Handley, Larry, Bawden, Gerald, Morgan, Karen, and Queija, Vivian, 2004, Report of the U.S. Geological Survey Lidar workshop sponsored by the Land Remote Sensing Program and held in St. Petersburg, FL, November 2002: U.S. Geological Survey Open-File Report 2004-1456, 72 p. Nayegandhi, Amar, Brock, J.C., and Wright, C.W., 2009, Small-footprint, waveform-resolving Lidar estimation of submerged and sub-canopy topography in coastal environments: International Journal of Remote Sensing, v. 30, no. 4, p. 861-878. Sallenger, A.H., Wright, C.W., and Lillycrop, Jeff, 2005, Coastal impacts of the 2004 hurricanes measured with airborne Lidar; initial results: Shore and Beach, v. 73, nos. 2-3, p. 10-14. Resources Included Readme.txt File

  11. Deformation of quartz and feldspar at mid-crustal depths in an extensional normal fault (Viveiro Fault, NW Spain)

    Science.gov (United States)

    López-Sánchez, M. A.; Llana-Fúnez, S.; Marcos, A.; Martínez, F. J.

    2012-04-01

    iii) cataclasis with precipitation of K-feldspar in fractures and other dilatational sites in plagioclase. Ultramylonites consist of a matrix mainly containing feldspar, quartz and micas (mainly biotite) with an average grain size below 15 μm, usually featuring some quartz pods and small feldspar porphyroclast. Quartz pods disintegrate into polycrystalline aggregates, and the resultant grains are mixed into the surrounding matrix reaching its average grain size. In the matrix, grain size is uniform and the distribution of mineral phases tends to be homogeneous. Mass balance analysis based on major elements indicates that the deformation process was not isochemical for some elements. Preliminary XRF results show that the mylonitic/ultramylonitic samples are depleted in Na and Mn and enriched in K and Ca respect to the original protolith, while others remains stable (Si, Al or Fe). This data suggests a large-scale transport of some components, and therefore, that fluids were involved during deformation. Similar feldspar microstructures in mylonites, implying cataclasis and neocrystallisation, have been previously reported in natural rocks where the temperature was estimated between 250 to 450°C (see Fitz-Gerald and Stünitz 1993, Hippertt 1998 or Ree et al. 2005). In opposition to this, petrological and mineralogical thermometry data indicate that temperatures during deformation of FV reached at 500-600°C, extending the temperature range previously reported.

  12. Capture and Geological Storage of CO2

    International Nuclear Information System (INIS)

    Kerr, T.; Brockett, S.; Hegan, L.; Barbucci, P.; Tullius, K.; Scott, J.; Otter, N.; Cook, P.; Hill, G.; Dino, R.; Aimard, N.; Giese, R.; Christensen, N.P.; Munier, G.; Paelinck, Ph.; Rayna, L.; Stromberg, L.; Birat, J.P.; Audigane, P.; Loizzo, M.; Arts, R.; Fabriol, H.; Radgen, P.; Hartwell, J.; Wartmann, S.; Drosin, E.; Willnow, K.; Moisan, F.

    2009-01-01

    To build on the growing success of the first two international symposia on emission reduction and CO 2 capture and geological storage, held in Paris in 2005 and again in 2007, IFP, ADEME and BRGM organised a third event on the same topic the 5-6 November 2009. This time, the focus was on the urgency of industrial deployment. Indeed, the IPCC 4. assessment report indicates that the world must achieve a 50 to 85% reduction in CO 2 emissions by 2050 compared to 2000, in order to limit the global temperature increase to around 2 deg. C. Moreover, IPCC stresses that a 'business as usual' scenario could lead to a temperature increase of between 4 deg. C to 7 deg. C across the planet. The symposium was organized in 4 sessions: Session I - Regulatory framework and strategies for enabling CCS deployment: - CCS: international status of political, regulatory and financing issues (Tom Kerr, IEA); - EC regulatory framework (Scott Brockett, European Commission, DG ENV); - Canada's investments towards implementation of CCS in Canada (Larry Hegan, Office of Energy Research and Development - Government of Canada); - A power company perspective (Pietro Barbucci, ENEL); - EC CCS demonstration network (Kai Tullius, European Commission, DG TREN); - Strategies and policies for accelerating global CCS deployment (Jesse Scott, E3G); - The global CCS Institute, a major initiative to facilitate the rapid deployment of CCS (Nick Otter, GCCSI); Session II - From pilot to demonstration projects: - Otway project, Australia (David Hilditch, CO2 CRC); - US regional partnerships (Gerald Hill, Southeast Regional Carbon Sequestration Partnership - SECARB); - CCS activities in Brazil (Rodolfo Dino, Petrobras); - Lessons learnt from Ketzin CO2Sink project in Germany (Ruediger Giese, GFZ); - CO 2 storage - from laboratory to reality (Niels-Peter Christensen, Vattenfall); - Valuation and storage of CO 2 : A global project for carbon management in South-East France (Gilles Munier, Geogreen); Session III

  13. Book Reviews

    Directory of Open Access Journals (Sweden)

    Jan Knappert

    1973-01-01

    Full Text Available - M. Heerma van Voss, J. Vergote, De godsdienst van de Egyptenaren. Romen, Roermond 1971. 125 p., plaat op omslag. - W. Thoden van Velzen-van Wetering, Alan Harwood, Witchcraft, sorcery and social categories among the Safwa. Oxford University Press for the International African Institute, London 1970. 160 p. - J.G. Oosten, E.E. Evans Pritchard, Nuer Religion, Clarendon Press, Oxford University Press, Oxford 1970. 335 p., 15 pl., 5 figs. - A.A. Trouwborst, Robert Brain, Bangwa Funerary Sculpture. Art and Society Series, Edited by Peter J. Ucko. Gerald Duckworth & Company Limited, London 1971, XII en 148 pp., plates, figures, colour plates., Adam Pollock (eds. - A.A. Trouwborst, E.E. Evans-Pritchard, The Azande. History and political institutions. Oxford University Press, London 1971. 444 pages, maps, figures, plates. - John Beattie, Jack Goody, Technology, tradition and the state in Africa. Oxford University Press for the International African Institute, London 1971. 88 pp. - D.H. Reader, Mia Brandel-Syrier, Reeftown elite: A study of social mobility in a modern African community on the Reef. Routledge and Kegan Paul, London 1971. 335 p., 4 figs. - R. Buijtenhuijs, Ariane Deluz, Organisation sociale et tradition orale: Les Guro de Côte d’Ivoire. Cahiers de l’Homme, Mouton et Co., Paris-La Haye 1970, 196 p. - John Beattie, Samwiri Rubaraza Karugire, A history of the Kingdom of Nkore in Western Uganda to 1896. Clarendon Press, Oxford Studies in African Affairs, Oxford 1971. 291 pp. - Jan Vansina, D.W. Cohen, The historical tradition of Busoga. Mukama and Kintu. (Oxford Studies in African Affairs, Clarendon Press: Oxford Univesity Press, Oxford 1972. Pp. X + 218, 9 kaartjes. - Th. Gerold-Scheepers, Alexander Alland jr., Adaptation in cultural evolution: an approach to medical anthropology. Columbia University Press, New York and London, 1970. IX + 188 p. and 6 p. bibliography. - J. Prins, Heribert Adam, South Africa. Sociological Perspectives

  14. A One Health overview, facilitating advances in comparative medicine and translational research.

    Science.gov (United States)

    Stroud, Cheryl; Dmitriev, Igor; Kashentseva, Elena; Bryan, Jeffrey N; Curiel, David T; Rindt, Hans; Reinero, Carol; Henry, Carolyn J; Bergman, Philip J; Mason, Nicola J; Gnanandarajah, Josephine S; Engiles, Julie B; Gray, Falon; Laughlin, Danielle; Gaurnier-Hausser, Anita; Wallecha, Anu; Huebner, Margie; Paterson, Yvonne; O'Connor, Daniel; Treml, Laura S; Stannard, James P; Cook, James L; Jacobs, Marc; Wyckoff, Gerald J; Likins, Lee; Sabbagh, Ubadah; Skaff, Andrew; Guloy, Amado S; Hays, Harlen D; LeBlanc, Amy K; Coates, Joan R; Katz, Martin L; Lyons, Leslie A; Johnson, Gayle C; Johnson, Gary S; O'Brien, Dennis P; Duan, Dongsheng; Calvet, James P; Gandolfi, Barbara; Baron, David A; Weiss, Mark L; Webster, Debra A; Karanu, Francis N; Robb, Edward J; Harman, Robert J

    2016-08-01

    A1 One health advances and successes in comparative medicine and translational researchCheryl StroudA2 Dendritic cell-targeted gorilla adenoviral vector for cancer vaccination for canine melanomaIgor Dmitriev, Elena Kashentseva, Jeffrey N. Bryan, David T. CurielA3 Viroimmunotherapy for malignant melanoma in the companion dog modelJeffrey N. Bryan, David Curiel, Igor Dmitriev, Elena Kashentseva, Hans Rindt, Carol Reinero, Carolyn J. HenryA4 Of mice and men (and dogs!): development of a commercially licensed xenogeneic DNA vaccine for companion animals with malignant melanomaPhilip J. BergmanA5 Successful immunotherapy with a recombinant HER2-expressing Listeria monocytogenes in dogs with spontaneous osteosarcoma paves the way for advances in pediatric osteosarcomaNicola J. Mason, Josephine S. Gnanandarajah, Julie B. Engiles, Falon Gray, Danielle Laughlin, Anita Gaurnier-Hausser, Anu Wallecha, Margie Huebner, Yvonne PatersonA6 Human clinical development of ADXS-HER2Daniel O'ConnorA7 Leveraging use of data for both human and veterinary benefitLaura S. TremlA8 Biologic replacement of the knee: innovations and early clinical resultsJames P. StannardA9 Mizzou BioJoint Center: a translational success storyJames L. CookA10 University and industry translational partnership: from the lab to commercializationMarc JacobsA11 Beyond docking: an evolutionarily guided OneHealth approach to drug discoveryGerald J. Wyckoff, Lee Likins, Ubadah Sabbagh, Andrew SkaffA12 Challenges and opportunities for data applications in animal health: from precision medicine to precision husbandryAmado S. GuloyA13 A cloud-based programmable platform for healthHarlen D. HaysA14 Comparative oncology: One Health in actionAmy K. LeBlancA15 Companion animal diseases bridge the translational gap for human neurodegenerative diseaseJoan R. Coates, Martin L. Katz, Leslie A. Lyons, Gayle C. Johnson, Gary S. Johnson, Dennis P. O'BrienA16 Duchenne muscular dystrophy gene therapyDongsheng DuanA17 Polycystic

  15. The Mount Logan (Yukon) Ice Cores: Preliminary Results

    Science.gov (United States)

    Fisher, D. A.

    2004-05-01

    Bourgeois, Mike Demuth, David Fisher, Roy Koerner,Chris Zdanowicz, James Zheng. University of Ottawa: Ian Clarke,Raphaelle Cardyn. National Institute of Polar Research (Japan): Kumiko Goto-Azuma University of New Hampshire: Cam Wake, Kaplan Yalcin. University of Maine: Karl Kreutz, Paul Mayewski, Erich Osterberg. Arctic Institute of North America: Gerald Holdsworth. University of Washington: Eric J. Steig, Summer B. Rupper. University of Copenhagen: Dorthe Dahl-Jensen. David Fisher is the presenter but many contributed to what is a joint preliminary offering.

  16. EDITORIAL: 15th Workshop on MHD Stability Control: 3D Magnetic Field Effects in MHD Control 15th Workshop on MHD Stability Control: 3D Magnetic Field Effects in MHD Control

    Science.gov (United States)

    Buttery, Richard

    2011-08-01

    ://fusion.gat.com/conferences/mhd10/. The Program Committee deeply appreciates the participation and support our community continues to show in this workshop. This year's meeting attracted a record number of talks, and we feel the workshop provides an unparalleled opportunity for in-depth discussion amongst the stability community. We would also like to thank our hosts this year—the University of Wisconsin, and in particular Professor Francesco Volpe—for the outstanding support and facilities. Finally, the opportunity was taken to rotate the membership of the Program Committee; we would like to thank outgoing members Professors Gerald Navratil, John Sarff and François Waelbroeck for their many years of excellent advice and service. Their contributions have helped make the workshop a stimulating and friendly environment, which will no doubt continue to press forward on the critical questions of plasma stability for fusion energy.

  17. A Multidimensional Tool Based on the eHealth Literacy Framework: Development and Initial Validity Testing of the eHealth Literacy Questionnaire (eHLQ).

    Science.gov (United States)

    Kayser, Lars; Karnoe, Astrid; Furstrand, Dorthe; Batterham, Roy; Christensen, Karl Bang; Elsworth, Gerald; Osborne, Richard H

    2018-02-12

    strongly on their respective factors. The IRT analysis showed that no items were found to have disordered thresholds. For most scales, discriminant validity was acceptable; however, 2 pairs of dimensions were highly correlated; dimensions 1 and 5 (r=.95), and dimensions 6 and 7 (r=.96). All dimensions were retained because of strong content differentiation and potential causal relationships between these dimensions. There is no evidence of DIF. The eHealth Literacy Questionnaire (eHLQ) is a multidimensional tool based on a well-defined a priori eHLF framework with robust properties. It has satisfactory evidence of construct validity and reliable measurement across a broad range of concepts (using both CTT and IRT traditions) in various groups. It is designed to be used to understand and evaluate people's interaction with digital health services. ©Lars Kayser, Astrid Karnoe, Dorthe Furstrand, Roy Batterham, Karl Bang Christensen, Gerald Elsworth, Richard H Osborne. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 12.02.2018.

  18. PREFACE: 22nd International Congress on X-Ray Optics and Microanalysis

    Science.gov (United States)

    Falkenberg, Gerald; Schroer, Christian G.

    2014-04-01

    fees low and to distribute eight student travel grants. The Wednesday was devoted to an outing to DESY with guided tours to PETRA III and FLASH experiments and to the European XFEL construction site. A lecture was given by Henry Chapman introducing to structural imaging at X-ray free-electron lasers. Talks highlighting the current status and future of nanoanalysis at the leading synchrotron facilities APS (J Maser), ESRF (P Cloetens) and SPRing8 (Ishikawa) were given in the DESY auditorium offering other DESY scientists the opportunity to follow the talks. Participants A higher quality version of this image is available in supplementary data Further information about ICXOM22, including a detailed program and electronic abstract book, can be found on the congress website www.icxom22.de. We thank all the participants of ICXOM22, everybody who helped in the organization and are looking forward to hearing about further progress during ICXOM23, which will be organized by Brookhaven National Laboratory in Uptown, New York. Gerald Falkenberg ICXOM22 conference chair Christian Schroer ICXOM22 co-chair

  19. CALIPSO Borehole Instrumentation Project at Soufriere Hills Volcano, Montserrat, BWI: Data Acquisition, Telemetry, Integration, and Archival Systems

    Science.gov (United States)

    Mattioli, G. S.; Linde, A. T.; Sacks, I. S.; Malin, P. E.; Shalev, E.; Elsworth, D.; Hidayat, D.; Voight, B.; Young, S. R.; Dunkley, P. N.; Herd, R.; Norton, G.

    2003-12-01

    The CALIPSO Project (Caribbean Andesite Lava Island-volcano Precision Seismo-geodetic Observatory) has greatly enhanced the monitoring and scientific infrastructure at the Soufriere Hills Volcano, Montserrat with the recent installation of an integrated array of borehole and surface geophysical instrumentation at four sites. Each site was designed to be sufficiently hardened to withstand extreme meteorological events (e.g. hurricanes) and only require minimum routine maintenance over an expected observatory lifespan of >30 y. The sensor package at each site includes: a single-component, very broad band, Sacks-Evertson strainmeter, a three-component seismometer ( ˜Hz to 1 kHz), a Pinnacle Technologies series 5000 tiltmeter, and a surface Ashtech u-Z CGPS station with choke ring antenna, SCIGN mount and radome. This instrument package is similar to that envisioned by the Plate Boundary Observatory for deployment on EarthScope target volcanoes in western North America and thus the CALIPSO Project may be considered a prototype PBO installation with real field testing on a very active and dangerous volcano. Borehole sites were installed in series and data acquisition began immediately after the sensors were grouted into position at 200 m depth, with the first completed at Trants (5.8 km from dome) in 12-02, then Air Studios (5.2 km), Geralds (9.4 km), and Olveston (7.0 km) in 3-03. Analog data from the strainmeter (50 Hz sync) and seismometer (200 Hz) were initially digitized and locally archived using RefTek 72A-07 data acquisition systems (DAS) on loan from the PASSCAL instrument pool. Data were downloaded manually to a laptop approximately every month from initial installation until August 2003, when new systems were installed. Approximately 0.2 Tb of raw data in SEGY format have already been acquired and are currently archived at UARK for analysis by the CALIPSO science team. The July 12th dome collapse and vulcanian explosion events were recorded at 3 of the 4

  20. Characterization of drug-release kinetics in trabecular bone from titania nanotube implants

    Directory of Open Access Journals (Sweden)

    Aw MS

    2012-09-01

    Full Text Available Moom Sinn Aw,1 Kamarul A Khalid,2,3 Karan Gulati,1 Gerald J Atkins,2 Peter Pivonka,4 David M Findlay,2 Dusan Losic11School of Chemical Engineering, 2Discipline of Orthopaedics and Trauma, The University of Adelaide, Adelaide, SA, Australia; 3Department of Orthopaedics, Traumatology and Rehabilitation, Faculty of Medicine, International Islamic University Malaysia, Kuantan, Pahang, Malaysia; 4Engineering Computational Biology Group, School of Computer Science and Software Engineering, The University of Western Australia, Perth, WA, AustraliaPurpose: The aim of this study was to investigate the application of the three-dimensional bone bioreactor for studying drug-release kinetics and distribution of drugs in the ex vivo cancellous bone environment, and to demonstrate the application of nanoengineered titanium (Ti wires generated with titania nanotube (TNT arrays as drug-releasing implants for local drug deliveryMethods: Nanoengineered Ti wires covered with a layer of TNT arrays implanted in bone were used as a drug-releasing implant. Viable bovine trabecular bone was used as the ex vivo bone substrate embedded with the implants and placed in the bone reactor. A hydrophilic fluorescent dye (rhodamine B was used as the model drug, loaded inside the TNT–Ti implants, to monitor drug release and transport in trabecular bone. The distribution of released model drug in the bone was monitored throughout the bone structure, and concentration profiles at different vertical (0–5 mm and horizontal (0–10 mm distances from the implant surface were obtained at a range of release times from 1 hour to 5 days.Results: Scanning electron microscopy confirmed that well-ordered, vertically aligned nanotube arrays were formed on the surface of prepared TNT–Ti wires. Thermogravimetric analysis proved loading of the model drug and fluorescence spectroscopy was used to show drug-release characteristics in-vitro. The drug release from implants inserted into bone ex

  1. Editors page

    Directory of Open Access Journals (Sweden)

    Margarita Barretto

    2007-09-01

    aculturação supostamente provocados pelo Turismo. É preciso, no entanto, verificar a relação da aculturação coma história social e a auto-estima dos povos. Na década de 1980 os defensores da chamada plataforma da conciliação propuseram novas formas de Turismo, que permitissem a convivência dos visitantes com os visitados. No entanto, é preciso ainda avaliart qual a influência dos preconceitos e estereótipos no relacionamento destes, assim como qual o limite da possibilidade de conviv~encia antes que a mes ma se transforme em invasão de privacidade. É necessário estar atento às implicações na área da saúde de novas formas de turismo rural, por exemplo. E, fundamentalmente, verificar qual o limite aceitável da turistificação de espaços e costumes. Sabemos que a resposta a estas questões não é fácil de se obter, porque é muito difícil isolar o turismo de outros fenômenos sociais coadjunvantes que podem ou não ter com ele uma relação causal. Apesar das dificuldades inerentes à pesquisa na área de Turismo temos certeza de que estamos trilhando o caminho, com uma comunidade científica que se esforça por investigar seriamente este objeto, fascinante por sua complexidade e diversidade. O formato eletrônico da Revista Brasileira de Pesquisa em Turismo, conjugado comn a gratuidade, permitirá o acesso livre e irrestrito por parte de todos os interessados, em qualquer parte do mundo, propiciando assim a difusão ampla do conhecimento asem barreiras físicas ou econômicas, o que é missão de uma associação de classe. No primeiro número, apresentamos artigos versando sobre educação, ensino, souvenirs, memória coletiva e museus. O artigo de Ari da Silva Fonseca FIlho apresenta um panorama da educação para o Turismo no ensino básico, concluindo que os programas desenvolvidos formam. ao mesmo tempo, bons turistas e bons anfitriões. A análise dos souvenirs realizada por Bianca Freire-Medeiros e Celso castro permite ver como estes comp

  2. A Biography of Distinguished Scientist Gilbert Newton Lewis (by Edward S. Lewis)

    Science.gov (United States)

    Harris, Reviewed By Harold H.

    1999-11-01

    reminded that quality counts, too. His story deserves much greater recognition (he should have won a Nobel of his own) and I am happy to see the appearance of this biography. On the other hand, it is unfortunate that a better book did not result from the author's heartfelt best intentions. Edward Lewis covers his father's career in barely over 100 pages of uninspiring prose. Ten percent of that is wasted in printing letters from famous scientists, many of them Lewis's students and Nobel laureates, endorsing the greatness of their colleague. Even the title of the book is off-putting: if the subject of a biography is "distinguished", it should not be necessary to make the claim in the title. I also wonder at the price of this slim volume. In the more than fifty years since Lewis died in 1946, nearly all of his students have also died. Even his chemist son had difficulty in finding contemporaries of his father who could provide recollections and original material for the history. The best of his sources is this Journal, which published in January-March issues of 1984 the proceedings of a symposium on the life and work of G. N. Lewis that had been held March 30-31, 1982, in Las Vegas. I recommend those papers, by Derek Davenport, Richard Lewis (G. N.'s other chemist son), John Servos, Melvin Calvin, Glenn Seaborg, Gerald Branch, Leo Brewer, Kenneth Pitzer, Jacob Bigeleisen, Anthony Stranges, Linus Pauling, William Jensen, and Michael Kasha.

  3. Obituary: Ronald Eugene Pitts, 1949-2008

    Science.gov (United States)

    MacConnell, D. Jack

    2009-01-01

    Silicon" under the direction of Gerald Newsom, and he was awarded the PhD in 1979. Newson recalls his facility with instrumentation, designing new circuitry to solve problems with the shock tube and ferreting out sources of systematic errors, and that it was enjoyable to work with him. In the fall of 1979, Ron went to Ball State University where he taught undergraduate astronomy classes for four years. In the summer of 1983, Ron left academia for the position of IUE Resident Astronomer with Computer Sciences Corporation [CSC] at the Goddard Space Flight Center where he joined a small contingent of other Ohio State graduates. For the next eleven years, he supported guest observers, implemented work-arounds as the IUE gyroscopes failed, improved calibrations, and had several proposals accepted to obtain spectra of spectrophotometric standards and to observe upper-main-sequence stars in the Pleiades, a Per, and NGC 2244, work that he did with Nancy Remage Evans. Ron worked diligently on the software to combine the best IUE calibration with ground-based data of the hot cluster stars and to fit the temperature and gravity. He also became interested in advanced technology for lunar remote telescopes and co-authored several studies with Peter Chen and others. After their children were of school age, Ron's wife Pat also worked for CSC/IUE for part of this period. In October 1994, Ron transferred to the Space Telescope Science Institute in Baltimore, Maryland, where he joined the science instrument commanding group under the direction of Vicki Balzano. His first task was helping to write the commanding software controlling the Space Telescope Imaging Spectrograph to be installed in HST in February 1997, and he became the in-house expert on the workings of this complex instrument, in particular on the details of the time-tag mode. In time, he became familiar with all the on-board instruments and oversaw the approval of the instrument commanding before the weekly HST command loads

  4. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1992-01-01

    Full Text Available -Selwyn R. Cudjoe, John Thieme, The web of tradition: uses of allusion in V.S. Naipaul's fiction, -A. James Arnold, Josaphat B. Kubayanda, The poet's Africa: Africanness in the poetry of Nicolás Guillèn and Aimé Césaire. Westport CT: Greenwood, 1990. xiv + 176 pp. -Peter Mason, Robin F.A. Fabel, Shipwreck and adventures of Monsieur Pierre Viaud, translated by Robin F.A. Fabel. Pensacola: University of West Florida Press, 1990. viii + 141 pp. -Alma H. Young, Robert B. Potter, Urbanization, planning and development in the Caribbean, London: Mansell Publishing, 1989. vi + 327 pp. -Hymie Rubinstein, Raymond T. Smith, Kinship and class in the West Indies: a genealogical study of Jamaica and Guyana, Cambridge: Cambridge University Press, 1988. xiv + 205 pp. -Shepard Krech III, Richard Price, Alabi's world, Baltimore and London: Johns Hopkins University Press, 1990. xx + 445 pp. -Graham Hodges, Sandra T. Barnes, Africa's Ogun: Old world and new, Bloomington & Indianapolis: Indiana University Press, 1989. xi + 274 pp. -Pamela Wright, Philippe I. Bourgois, Ethnicity at work: divided labor on a Central American banana plantation, Baltimore MD: John Hopkins University Press, 1989. xviii + 311 pp. -Idsa E. Alegría-Ortega, Andrés Serbin, El Caribe zona de paz? geopolítica, integración, y seguridad, Caracas: Editorial Nueva Sociedad, 1989. 188 pp. (Paper n.p. [Editor's note. This book is also available in English: Caribbean geopolitics: towards security through peace? Boulder CO: Lynne Rienner, 1990. -Gary R. Mormino, C. Neale Ronning, José Martí and the émigré colony in Key West: leadership and state formation, New York; Praeger, 1990. 175 pp. -Gary R. Mormino, Gerald E. Poyo, 'With all, and for the good of all': the emergence of popular nationalism in the Cuban communities of the United States, 1848-1898, Durham NC: Duke University Press, 1989. xvii + 182 pp. -Fernando Picó, Raul Gomez Treto, The church and socialism in Cuba, translated from

  5. Obituary: Alan D. Fiala (1942-2010)

    Science.gov (United States)

    Kaplan, George

    2011-12-01

    Dr. Alan Dale Fiala, astronomer and expert on solar eclipses, died on May 26, 2010 in Arlington, Virginia, of respiratory failure after a brief illness. He was 67. Fiala had been a staff astronomer at the U.S. Naval Observatory in Washington, D.C., for his entire professional career, where he rose from a position as a summer intern to become the Chief of the Nautical Almanac Office, responsible for annual publications for astronomy and navigation that are used the world over. He retired from the observatory in 2000. Although a childhood case of polio affected his mobility for the rest of his life, he seldom let his physical constraints limit his activities, which were many and varied. Alan Fiala was born in Beatrice, Nebraska on November 9, 1942, the middle son of Emil A. ("John") and Lora Marie Fiala. Fiala's father was a postal clerk and Civil Service examiner. Fiala expressed interest in astronomy at a very young age. He contracted polio when he was 9. He graduated from Beatrice High School in 1960 with a straight-A average and went on to study at Carleton College. He received his B.A. summa cum laude after three years, in 1963, with a major in astronomy and minors in physics and mathematics. He was elected to Phi Beta Kappa, Sigma Xi, and Pi Mu Epsilon (mathematics). In 1962, Alan Fiala obtained a job as a summer intern at the Naval Observatory in Washington, working in the Nautical Almanac Office (NAO). He entered the graduate program at Yale University and continued to work summers at the observatory. He received his Ph.D. in 1968, under Gerald Clemence. His dissertation was titled "Determination of the Mass of Jupiter from a Study of the Motion of 57 Mnemosyne." After receiving his doctorate, Fiala became a permanent member of the Naval Observatory staff. Computers were just being introduced there and he participated in the automation of many procedures used to prepare the annual publications of the Nautical Almanac Office. One of his first assignments was

  6. What Did You Try Last Semester? How Did It Work?

    Science.gov (United States)

    Moore, John W.

    1999-02-01

    As I write this, the end of the semester is less than a week away. This is a good time to reflect on what I tried this time that I had not done before, how well it worked, and how that applies to the process of change and reform in chemical education. Nearly a year ago, a good friend gave me a copy of a brief note by the Executive Director of the National Science Teachers Association, Gerald Wheeler (1). Its title was "Why doesn't change stick?" Quoting the Red Queen from Alice in Wonderland, Wheeler suggested that it might be taking all the running we could do just to maintain the status quo. He asked readers to look systematically at "the failed reform efforts begun in the 1960s" and questioned whether those efforts had actually changed anything. Although the reform efforts Wheeler questioned were aimed at the pre-college level, his point is a good one for college as well as high school teachers to consider, especially at a time when new projects are aiming to reform science education systemically. (See pages 158-160 and page 163 for more information on these projects.) If reform efforts are typically meteoric, burning brightly for but a short time and then disappearing, what might we do to make them less so? I think that the power to make reform less meteoric lies within all of us. It involves incremental, rather than revolutionary, change. My model for reform is one in which each of us continually experiments with manageable changes in courses and pedagogy, evaluating their effectiveness, casting out the less than successful ones, retaining and refining those that help students learn more effectively, and keeping the rest of the community informed about what works and what does not. This model requires continual work and dedication from all of us, but not superhuman effort that is impossible to sustain over the long term. A meteor shower definitely gets our attention, but far more light is shed by the fixed stars, and they'll still be there next week. The

  7. 3. forum of radiation protection sciences - Book of abstracts

    International Nuclear Information System (INIS)

    2002-10-01

    This document brings together the abstracts of all presentations given at the 3. European forum of radiation protection sciences on the topic of radiation protection and dismantling logic: 1 - Organisation of dismantling operations financing at UP1 Marcoule (Jean Laurent, GIE CODEM); 2 - Dismantling strategy at the CEA - civil branch (Gerard Cerdan, CEA/DEN/DPA); 3 - Safety and radiation protection control during nuclear facilities dismantling (Estelle Chapalain, DGSNR); 4 - Regulatory evolutions in radiation protection (Marc Ammerich, DGSNR); 5 - Implementation of the ALARA approach in the BR3 reactor dismantling project (Vincent Massaut, SCK-CEN Mol, Belgium); 6 - Study of Super Phenix reactor block dismantling: radiological characterization (Fabrice Biagi, Framatome ANP; Herve Salliot, EDF CIDEN); 7 - Wastes characterization: prerequisites to main cleansing projects (Guy Andrieu, Cogema Marcoule); 8 - Radiation protection in relation with the definitive shutdown of UP1 Marcoule (Philipp Blaise, COGEMA Marcoule); 9 - Deconstruction of the Monts d'Arree power plant (Alain Ensuque, Monts d'Arree site, Brennilis); 10 - Presentation of the cleansing project of Marcoule's pilot workshop (Gerald Imbard, CEA Valrho); 11 - AT1 dismantling at Cogema La Hague (David Nolin, CEA Valrho); 12 - Dismantling management of the CERN-LEP - Large electron-positon collider (John Poole, CERN Switzerland); 13 - Level 3 dismantling of the TRITON facility (Elia Lopes, CEA FAR); 14 - Presentation of cleansing operations at Cogema Marcoule UP1 factory (Christine Georges, Cogema Marcoule); 15 - Decontamination strategy prior to the dismantling of the highly contaminated primary and auxiliary circuits of the BR3 PWR reactor (Pierre Valenduc, SCK-CEN Mol, Belgium); 16 - Nuclear submarines dismantling (Philippe Queau, DCN Cherbourg); 17 - Use of tele-operation in dismantling (Jean Marie Carrere, CEA Valrho); 18 - Design principle of tele-operated tools (Jean Paul Drogoul, Cogema Marcoule); 19

  8. An integrated modeling framework for real-time irrigation scheduling: the benefit of spectroscopy and weather forecasts

    Science.gov (United States)

    Brook, Anna; Polinova, Maria; Housh, Mashor

    2016-04-01

    and short-term weekly forecasts. In order to optimize the water resource use, the irrigation scheduling will be defined by use a simulation model of soil-plant and atmosphere system (e.g. SWAP model, Van Dam et al., 2008). The use of this tool is necessary to: i) take into account the soil spatial variability; ii) to predict the system behaviour under the forecasted climate; iii) define the optimized irrigation water volumes. Given this knowledge in the three domains of optimization under uncertainty, spectroscopy/remote sensing and climate forecasting, we will be presented as an integrated framework for deriving optimal irrigation decisions. References Nelson, Gerald C., et al. Climate change: Impact on agriculture and costs of adaptation. Vol. 21. Intl Food Policy Res Inst, 2009. Housh, Mashor, Avi Ostfeld, and Uri Shamir. "Seasonal multi-year optimal management of quantities and salinities in regional water supply systems." Environmental Modelling & Software 37 (2012): 55-67. Wang, Dingbao, and Ximing Cai. "Irrigation scheduling - Role of weather forecasting and farmers' behavior." Journal of Water Resources Planning and Management 135.5 (2009): 364-372. Van Dam, J. C., et al. SWAP version 3.2: Theory description and user manual. No. 1649. Wageningen, The Netherlands: Alterra, 2008.

  9. Fire history and climate variability during the Mid-Late Holocene in the Picos de Europa (Cantabrian Mountains, NW Spain), based on sedimentary sequence of Belbín

    Science.gov (United States)

    Ruiz-Fernández, Jesús; Nieuwendam, Alexandre; Oliva, Marc; Lopes, Vera; Cruces, Anabela; Conceição Freitas, Maria; Janeiro, Ana; López-Sáez, José Antonio; García-Hernández, Cristina

    2017-04-01

    ) texture and organic matter (OM) content, including labile and refractory OM, Rp index and C/N relation; 2) quartz grains microstructures; 3) Charcoal accumulation rate: macroscopic charcoal (>125 µm) was identified and counted from subsamples of 1 cm3 at every 1 cm depth by sediment sieving; 4) the geochronological framework was established with three samples selected for 14C accelerator mass spectrometry (AMS)-dating (Laval University, Canada). Oscillating warm and cold stages corresponding to the Mid-Late Holocene were identified in the study area. Warmer temperatures were recorded between 6.67-4.95 ky cal BP, 3.66-3.01, 2.58-1.06, 0.86-0.51, and 0.13 ky cal BP until nowadays, and colder regimes occurred between 4.95-3.66 ky cal BP, 3.01-2.58, 1.06-0.86 and 0.51-0.13. The warmer stages were defined by the dominance of chemical weathering of the quartz grains and relative increases of the C/N ratio, while colder stages corresponded to intense physical weathering of the quartz grains and lower C/N values. With exceptions, the organic content increased from bottom to top of the core. The charcoal particles didn't show a different concentration in colder or warmer conditions, which may be linked to human-induced fire management of the landscape. The most significant period of fire activity occurred between 3.5 and 3 ky cal BP, during the Bronce Age (other significant periods occurred at 2.6, 0.71 and 0.36 ky cal BP). References Ruiz-Fernández, J., Oliva, M., Cruces, A., Lopes, V., Freitas, M.C., Andrade, C., García-Hernández, C., López-Sáez, J.A., Geraldes, M. (2016). Environmental evolution in the Picos de Europa (Cantabrian Mountains, SW Europe) since the Last Glaciation. Quaternary Science Reviews, 138: 87-104.

  10. PREFACE: Preface

    Science.gov (United States)

    Angelova, Maia; Zakrzewski, Wojciech

    2011-03-01

    the meeting was that all plenary talks presented the state-of-the-art and were at the same time educational and exciting, promoting the multidisciplinary aspects of the research, and thus were inspirational for young scientists considering work in these fields. The plenary talks, each lasting 1 hour, were given by distinguished world experts and some young 'rising stars': Richard Ward, Ulf Leonhardt, Jens Eisert, Michael Berry, Shahn Majid, Arndt von Haeseler, Michio Jimbo, Katrin Wendland, Raymond Goldstein, Mark Trodden, Maria Vozmediano and Giulio Chiribella. The public lecture was given by Francesco Iachello and was open to participants and other people from the Newcastle-Durham region. In addition, talks of 30 minutes duration each and including more technical content, were given in four parallel sessions. Each parallel session had a designated time for informal interaction with the speakers, discussions of new directions of research and for forming new collaborations. The poster session, in a room where posters were exhibited for the duration of the conference, was easily accessible, and had a friendly and relaxed atmosphere, encouraging discussions of work and exchanges of new ideas. To secure a high quality scientific programme, all contributions were reviewed. Another interesting feature of the conference was the Open Forum on the Friday afternoon, which was lively and well attended. It took the form of a question and answer session with a panel chaired by Allan Solomon, with the following members: Gerald Goldin, Jean-Pierre Gazeau, Mark Trodden and Giulio Chiribella. The focus was on new directions of research, novel applications and the further development of group theory, education, training and career opportunities for young researchers. The participants were asked to submit questions in advance; examples are: "What is the role of symmetries and conservation principles in deducing underlying physics from experimental data?" and "What are the most

  11. FOREWORD: 12th International Workshop on Plasma-Facing Materials and Components for Fusion Applications 12th International Workshop on Plasma-Facing Materials and Components for Fusion Applications

    Science.gov (United States)

    Kreter, Arkadi; Linke, Jochen; Rubel, Marek

    2009-12-01

    with a great response: not only did over thirty young colleagues register but also senior scientists registered for the course and were very active in discussions. The workshop was supported financially by Forschungszentrum Jülich and the ExtreMat Integrated Project, a programme for the development and study of new materials for extreme environments. We are very grateful to the staff of Forschungszentrum who helped with the organization. Our most cordial thanks and gratitude go to Yasmin Fattah, Angelika Hallmanns, Gabriele Knauf and Gerd Boeling for all their kindness and efficiency, which helped all of us to enjoy the meeting. We thank most sincerely our colleagues Gerald Pintsuk, Takeshi Hirai and Andrey Litnovsky for their most professional work in the construction and operation of the conference webpage, the preparation of the sessions and for all other elements that were vital for the smooth running of the meeting. We thank very much Marliese Felden and Ralf-Uwe Limbach who very kindly and professionally took care of the photographic documentation of the workshop. The proceedings of this workshop contains 67 peer-reviewed articles covering the contents of most of the invited presentations and a number of poster contributions which were pre-selected by the programme committee. The papers reflect the development and actual status of the field. We thank all participants for their contributions and the referees for their smooth and efficient peer-review. Thank you all for your hard work and co-operation. We are looking forward to seeing you at the next meeting; we invite you to come, though we are not yet able to say 'when' and 'where' we will meet next time. It is a special feature of this conference series that a new meeting is announced only when the community feels that there is substantial new material to be presented and discussed.

  12. News & Announcements

    Science.gov (United States)

    2001-08-01

    and establishing its role in gene regulation; for his discovery of a giant complex of 20 proteins known as the "Mediator", which regulates the transcription process; and for determining the atomic structure of RNA polymerase II. The 300,000 award salutes Kornberg's lifetime contributions to biochemistry. NSTA Teacher Awards During its 2001 national convention the National Science Teachers Association presented prizes and awards to teachers for their exemplary teaching practices and commitment to quality science education. Many appear below. Distinguished Service to Science Education Award JoAnne Vasquez, Science Consultant, Gilbert, AZ Richard F. Duncan, Beaverton Administrative Center, Beaverton, OR Mitchell E. Batoff, New Jersey City University, Jersey City, NJ Distinguished Informal Science Education Award Al Stenstrup, Wisconsin Department of Natural Resources, Madison, WI Ciba Specialty Chemicals Education Foundation Exemplary Science Teaching Award, High School Level Gerald Friday, Marquette High School, Milwaukee, WI Gustav Ohaus Innovations in Science Teaching, High School Mark Stefanski, Marin Academy, San Rafael, CA (first place) James A. Szoka, Clarke County High School, Berryville, VA (second place) Gustav Ohaus Innovations in Science Teaching, College William F. McComas, University of Southern California, Los Angeles, CA (first place) Barbara M. Lom, Davidson College, Davidson, NC (second place) Courses, Seminars, Meetings, Opportunities Proposal Deadlines Proposal Deadlines will not appear this month. Readers should consult page 876 of the July 2001 issue or JCE Online. National Educators' Workshop The National Institute of Standards and Technology's Materials Science and Engineering Laboratory will host the 16th annual National Educators' Workshop (NEW: Update): Experiments in Engineering, Materials Science, and Technology. NEW: Update is part of the NIST centennial celebration. It will be held in Gaithersburg, MD, and at the University of Maryland

  13. New Book Recounts Exciting, Colorful History Of Radio Astronomy in Green Bank, West Virginia

    Science.gov (United States)

    2007-07-01

    size. The book reprints internal memos, reports, and recollections of astronomers who were there, as the initial elation turned to frustration when the 140 Foot Telescope project became mired in technical difficulties, plans for larger dishes were put on hold, and the scientific staff of the fledgling Observatory struggled to create a National Observatory with inadequate equipment in a very remote location. Articles by David Heeschen and John Findlay tell the story of the creation of the 300 Foot Telescope, at that time the largest in the world, which went from initial concept to full operation in only 23 months, and began a rich life of research that put the NRAO on the world scientific map. The 300 Foot Telescope was originally intended to be an interim instrument, but as documented in the book, demand for its use was so high that it was kept in operation long after its initial planned retirement, with regular upgrades and new generations of electronics. The sudden collapse of the 300 Foot Telescope on a calm evening after 26 years of operation shocked the astronomical community. But it was Fun... features dramatic first-hand accounts by the people who were there that night: the telescope operator who found himself under a falling structure; the Observatory staff who at first could not believe what happened, and those who worked during the night and into the next day to secure the area, preserve information on what happened, and deal with the rush of publicity. The book includes extensive photographs and the Executive Summary Report of the panel which was commissioned to investigate the collapse and its implication for the design of other large radio telescopes. But it was Fun... will appeal to a variety of audiences. Historians of science will be interested in the articles by David Heeschen, Gerald Tape, and Hugh van Horn, on the evolution of the concept of a National Observatory, and the difficulties of putting the concepts into practice in Green Bank. Those

  14. Obituary: Hans Albrecht Bethe, 1906-2005

    Science.gov (United States)

    Wijers, Ralph

    2007-12-01

    head-on and not allowing himself to be side-tracked by those who would deem the problem be much more complex and difficult, moving straight forward like an intellectual battleship ("The H.A. Bethe Way," as his collaborator Gerald E. Brown would dub the style). Bethe's involvement in the Project brought to light his abilities in the managerial and political arena, which he used later to much effect to influence the wider world; he was among those who fought hard during the Cold War to contain the impact of the terrible weapons he had helped invent. As his two children, Henry and Monica, were born, the war years also made him a family man. As his father did with him, he often took them on long walks, in the hills around Ithaca or further afield; he much enjoyed walking, and mountains. Just after the war, during and following the June 1947 Shelter Island Conference, Bethe made another of his great contributions to physics—some might say his greatest. The experiments by Willis Lamb and Robert Retherford, on what came to be known as the "Lamb shift," were discussed, and during the meeting the assembled crowd (Richard Feynman, Julian Schwinger, and Hendrick Kramers among them) got stuck on the infinities of QED. During the train ride home, Bethe managed to compute the correct answer by realizing that the complex QED machinery could be bypassed, the H.A. Bethe Way. His 1967 Nobel Prize spurred a brief revival of Bethe's interest in astrophysics, but his work in the following years continued to focus on nuclear physics and dense matter (and disarmament and nuclear power, of course). In 1978 he re-entered astrophysics with a bang: Bethe was losing interest in nuclear physics and, after a few years of trying, Gerry Brown lured him back to astrophysics during a stay at the Nordic Institute for Theoretical Physics (NORDITA). The refugee from Hitler and the refugee from McCarthy jointly attacked the problem of supernova collapse. Bethe had the crucial insight that the low entropy

  15. Abass Alavi: A giant in Nuclear Medicine turns 80 and is still going strong!

    Science.gov (United States)

    Høilund-Carlsen, Poul F

    2018-01-01

    previously assumed. Thus, in cancer, genetic profiling has demonstrated that tumors are genetically often a mixture of cellular clones and that these are not necessarily also present in local, regional or remote metastases, meaning that ultra-specific PET tracers for cancer diagnosis and staging may be more a utopian vision than a realistic future possibility. This, together with inborn limitations of the PET technique has made Abass Alavi more prudent and hesitant toward reports of highly promising new PET tracers and an advocate of timely carefulness when using our limited financial resources. Teaching and education of talented young individuals is one of Alavi's main academic missions. Thus, with Gerald Mandell, MD, he established the Alavi-Mandell Award, presented for the first time at the SNM meeting in 1999 to a candidate selected from among all those in a given year who were trainees at the time their names appeared as first authors of papers in JNM. Together with his wife Jane, Alavi established the Bradley-Alavi Student Fellowship which was presented for the first time in 2001 and is given to the top students selected by the SNMMI Education and Research Foundation. Alavi himself is a recipient of multiple awards, including the Georg Charles de Hevesy Nuclear Pioneer Award (2004), the Benedict Cassen Prize for Research in Nuclear Medicine (2012), the Honorary Citizenship of his native town Tabriz (2015) and the Gold Medal of the National Institute for Medical Research Development, Tehran (2015). In addition, he has received the Honorary PhD Degree in Molecular Biology of the University of Shiraz (2007), and the Honorary Doctoral Degrees of the University of Bologna (2007), the University of the Sciences in Philadelphia (2008), the Medical University of Gdansk (2016), and the University of Southern Denmark (2016). Since January 2011, Alavi has been a frequent guest in the city of Odense, Denmark. Its University Hospital holds one of the biggest departments of nuclear

  16. Obstacles and solutions to the generation and dissemination of scientific knowledge in poor countries

    Directory of Open Access Journals (Sweden)

    David L Nordstrom

    2012-10-01

    and middle-income countries are still opinion-based.Alas this is also all too often the case in the US and Western Europe. For example, little policy has developed in response to the growing threat from climate change to the health and the environment. The process from the discovery of scientific knowledge to its effects on human behavior is usually long and unpredictable. Current epidemiology training focuses on epidemiologic methods, with little attention on how the science of epidemiology is translated into effective health policy (Brownson, 1998, page 377. Actually, research findings always have some degree of uncertainty, and policy choices depend on many social, cultural, and economic factors, including people’s opinions and beliefs. Fortunately, expert guidance is available on ways to communicate research findings to the public and policymakers that increase the chance that good science will result in good public health (Nelson, 2011; Remington, et al., 2011; Brownson, et al., 2011. A somewhat contrary view is that researchers are not responsible for the translation of their findings into public policy and should enter the political fray cautiously (Rothman & Poole, 1985.5.The golden standard of studies generating such evidence is randomized controlled trials.Bonita et al (2006, page 95 distinguish between various study designs by ranking their ability to provide evidence for causality between an exposure and a disease: “strong” for randomized controlled trials, “moderate” for cohort and case-control studies, and “weak” for cross-sectional and ecological studies. However, Steven N Goodman of Stanford University and Gerald J Dal Pan of the US Food and Drug Administration, speakers at the 2012 American College of Epidemiology Annual Meeting, indicated that the traditional hierarchy of scientific evidence may be too simple. They argued that experiments have more limits than generally appreciated, and evidence from observational studies can also be

  17. 6th International Symposium on Molecular Allergology (ISMA

    Directory of Open Access Journals (Sweden)

    Christiane Hilger

    2016-10-01

    hypoallergenic variant of the major peanut allergen Ara h 2 for allergen-specific immunotherapy Angelika Tscheppe, Dieter Palmberger, Merima Bublin, Christian Radauer, Chiara Palladino, Barbara Gepp, Nina Lengger, Reingard Grabherr, Heimo Breiteneder P36 Mutagenesis of amino acids critical for calcium-binding leads to the generation of a hypoallergenic Phl p 7 variant Marianne Raith, Linda Sonnleitner, Doris Zach, Konrad Woroszylo, Margit Focke-Tejkl, Herbert Wank, Thorsten Graf, Annette Kuehn, Ines Swoboda P37 Are birch pollen allergen immunotherapy induced blocking antibodies protective for cross-reactive allergens? Claudia Asam, Sara Huber, Heidi Hofer, Roland Lang, Thomas Hawranek, Fátima Ferreira, Michael Wallner P38 High success of 58 subcutaneous immunotherapy for pets allergy in a polyallergic cohort of patients: a component resolved individually adapted treatment (CRIAT Fabienne Gay-Crosier P39 Neutrophils are potential antigen presenting cells in IgE- mediated allergy Dominika Polak, Birgit Nagl, Claudia Kitzmüller, Barbara Bohle P40 Characterization of allergen-specific CD8+ T cells in type I allergy Nazanin Samadi, Claudia Kitzmüller, Rene Geyeregger, Barbara Bohle, Beatrice Jahn-Schmid Poster Session 5: Molecular and cellular diagnostic tests P41 Nanofluidic-based biosensors allow quantification of total circulating IgE from a drop of blood in 5 minutes Aurélie Buchwalder, Ariel Gomez, Fabien Rebeaud, Iwan Märki P42 Allergen microarray for the analysis of serum IgE binding profile and allergenic activity Jaana Haka, Liisa Hattara, Marika Heikkinen, Merja H Niemi, Juha Rouvinen, Petri Saviranta, Pekka Mattila, Kristiina Takkinen, Marja-Leena Laukkanen P43 Generation of a well-characterized panel of periplaneta americana allergens for component resolved diagnosis Stephanie Eichhorn, Isabel Pablos, Bianca Kastner, Bettina Schweidler, Sabrina Wildner, Peter Briza, Jung-Won Park, Naveen Arora, Stefan Vieths, Gabriele Gadermaier, Fatima Ferreira P44 Improved

  18. PREFACE: XVth International Conference on Calorimetry in High Energy Physics (CALOR2012)

    Science.gov (United States)

    Akchurin, Nural

    2012-12-01

    Livan, Pavia Univ. & INFN Pasquale Lubrano, INFN Perugia Steve Magill, ANL Amelia Maio, LIPP Lisbon Horst Oberlack, MPI Munich Adam Para, FNAL Klaus Pretzl, Univ. of Bern Yifang Wang, IHEP Beijing Richard Wigmans, TTU Ren-Yuan Zhu, Caltech Local Organizing Committee: Nural Akchurin, TTU Debra Boyce, TTU (Secretary) Xiadong Jiang, LANL Jon Kapustinsky, LANL Sung-Won Lee, TTU Sally Seidel, UNM Igor Volobouev, TTU Session Conveners: LHC I-III: David Barney (CERN) Ana Henriques (CERN) Sally Seidel (UNM) Calorimetry Techniques I-II: Francesca Tedaldi (ETH-Zurich) Tao Hu (IHEP-Beijing) Calorimetry Techniques III-IV: Craig Woody (BNL) Tohru Takeshita (Shinshu) Astrophysics and Neutrinos: Don Groom (LBNL) Steve Magill (ANL) Operating Calorimeters: Jordan Damgov (TTU) Gabriella Gaudio (INFN-Pavia) Frank Chlebana (FNAL) Algorithms and Simulations: Artur Apresyan (Caltech) Igor Volobouev (TTU) Front-end and Trigger: Chris Tully (Princeton) Kejun Zhu (IHEP-Beijing) Future Calorimetry: Michele Livan (Pavia Univ.) Frank Simon (MPI) Vishnu Zutshi (NICADD) List of Participants: ABOUZEID, Hass University of Toronto AKCHURIN, Nural Texas Tech University ANDEEN, Timothy Columbia University ANDERSON, Jake Fermilab APRESYAN, Artur California Institute of Technology AUFFRAY, Etiennette CERN BARILLARI, Teresa Max-Planck-Inst. fuer Physik BARNEY, David CERN BESSON, Dave University of Kansas BOYCE, Debra Texas Tech University BRUEL, Philippe LLR, Ecole Polytechnique, CNRS/IN2P3 BUCHANAN, Norm Colorado State University CARLOGANU, Cristina LPC Clermont Ferrand / IN2P3 / CNRS CHEFDEVILLE, Maximilien CNRS/IN2P3/LAPP CHLEBANA, Frank Fermilab CLARK, Jonathan Texas Tech University CONDE MUINO, Patricia LIP-Lisboa COWDEN, Christopher Texas Tech University DA SILVA, Cesar Luiz Los Alamos National Lab DAMGOV, Jordan Texas Tech University DAVYGORA, Yuriy University of Heidelberg DEMERS, Sarah Yale University EIGEN, Gerald University of Bergen EUSEBI, Ricardo Texas A&M University FERRI, Federico CEA

  19. The 12th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof. Dr. Matei Bals” and the 12th National Infectious Diseases Conference

    Directory of Open Access Journals (Sweden)

    Cristian-Mihail Niculae

    2016-11-01

    microbiological agents on serum gangliosides in patients with benign prostate hyperplasia Corina-Daniela Ene, Cosmin-Victor Ene, Roxana Simona Georgescu, Marilena Ciortea , Lucreția Dulgheru, Ilinca Nicolae A110 Toxocariasis - the experience of the Iași Infectious Diseases Hospital between 2013–2015 Mihaela Cătălina Luca, Ioana-Alina Harja-Alexa, Roxana Nemescu, Mădălina Popazu, Andrei Ștefan Luca A111 Species of anaerobic Gram-positive cocci involved in odontogenic abscesses Gabriela Bancescu, Bogdan Dabu, Adrian Bancescu A112 Clostridium difficile infection recurrences Eliza Manea, Raluca Jipa, Adriana Hristea A113 Differential diagnosis of staphylococcal and tuberculous osteodiscitis – case report Adina Elena Ilie, Săftica-Mariana Pohrib, Alina Cristina Neguț, Maria-Sabina Tache, Maria Magdalena Moțoi, Oana Săndulescu, Ion Aurel Iliescu, Adrian Streinu-Cercel A114 Severe clinical forms of respiratory syncytial virus infections Cristina Tecu, Maria-Elena Mihai, Mihaela Lazăr, Carmen Cherciu, Alina Ivanciuc, Daniela Pițigoi, Emilia Lupulescu A115 Acinetobacter baumannii postoperative sepsis associated with Clostridium difficile enterocolitis in an immune suppressed elderly patient Mirela Paliu, Manuela Curescu, Bianca Cerbu, Iosif Marincu A116 Risk factors and their impact on psychopathology and quality of life among people living with HIV/AIDS in Romania Fulvia Ursoiu, Mirandolina Prișcă, George Ciprian Pribac A117 Antivirals susceptibility of influenza viruses circulating in Romania Maria Elena Mihai, Carmen Maria Cherciu, Alina Elena Ivanciuc, Cristina Tecu, Emilia Lupulescu A118 Retrospective study of hospitalized cases of sepsis at the Hospital Clinic of Infectious Diseases “Toma Ciorbă” Irina Bunescu, Tiberiu Holban, Ana Pasnin, Stela Semeniuc, Raisa Popovici, Galina Chiriacov